Mercurial > repos > arkarachai-fungtammasan > str_fm
comparison sequencingdepthconversion_G.py @ 0:07588b899c13 draft
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author | arkarachai-fungtammasan |
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date | Wed, 01 Apr 2015 17:05:51 -0400 |
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-1:000000000000 | 0:07588b899c13 |
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1 def stop_err(msg): | |
2 sys.stderr.write(msg) | |
3 sys.exit() | |
4 | |
5 def info2require(X,L,F,r): | |
6 '''infodepth,readlength,flanksize,repeatlength | |
7 ''' | |
8 return int(math.ceil((X*L*1.0)/(L-(1*((2*F)+r-1))))) | |
9 | |
10 def poissondef(meancov,specificcov): | |
11 nominator=1.0*(meancov**specificcov)*(math.e**(-1*meancov)) | |
12 denominator=math.factorial(specificcov) | |
13 return nominator/denominator | |
14 | |
15 def require2recommend(needprob,mindepth): | |
16 i=mindepth | |
17 reverseneedprob=1-needprob | |
18 sumprob=1 | |
19 while sumprob>reverseneedprob: #mean cov | |
20 sumprob=0 | |
21 for j in range(0,mindepth): #specific cov | |
22 sumprob+=poissondef(i,j) | |
23 i+=1 | |
24 | |
25 return i-1 | |
26 | |
27 import sys,math | |
28 | |
29 repeatlength=int(sys.argv[1]) | |
30 flanksize=int(sys.argv[2])#20 | |
31 readlength=int(sys.argv[3])#100 | |
32 infodepth=int(sys.argv[4])#5 | |
33 probdetection=float(sys.argv[5])#0.90 | |
34 | |
35 if probdetection >1: | |
36 try: | |
37 probvalue=int('probvalue') | |
38 except Exception, eee: | |
39 print eee | |
40 stop_err("Proportion of genome to have certain locus specific must be between 0 and 1") | |
41 | |
42 print 'repeat_length'+'\t'+'read_length'+'\t'+'informative_read_depth''\t'+'=locus_specific_sequencing_depth'+'\t'+'=genome_wide_sequencing_depth' | |
43 t_requiredepth=info2require(infodepth,readlength,flanksize,repeatlength) | |
44 t_recomendseq=require2recommend(probdetection,t_requiredepth) | |
45 preplotlist=[repeatlength,readlength,infodepth,t_requiredepth,t_recomendseq] | |
46 plotlist=map(str,preplotlist) | |
47 print '\t'.join(plotlist) | |
48 | |
49 #print info2require(infodepth,readlength,flanksize,repeatlength) | |
50 #print poissondef(10,3) | |
51 #print require2recommend(0.90,80) | |
52 #informative_read_depth | |
53 #required_seq_depth | |
54 #recommend_seq_depth |