Mercurial > repos > bgruening > hicexplorer_chicviewpoint

changeset 9:40fee49bc6c3 draft

Find changesets by keywords (author, files, the commit message), revision number or hash, or revset expression.
planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hicexplorer commit 8586409c5f329eaf75902eedc3d29a6e82560788
author iuc
date Mon, 01 Jul 2024 20:12:19 +0000
parents f881c94fb3b3
children c4ed35f4f77f
files macros.xml test-data/cHi-C/chicExportData/aggregate.tar.gz test-data/cHi-C/chicQualityControl/histogram.png test-data/cHi-C/chicQualityControl/new_referencepoints.bed_raw_filter test-data/cHi-C/chicQualityControl/new_referencepoints.bed_report test-data/cHi-C/chicQualityControl/sparsity.png test-data/cHi-C/plots.tar.gz test-data/cHi-C/target_list.bed test-data/hicAggregateContacts_results1.png test-data/hicCorrectMatrix/diagnostic_plot.png test-data/hicCorrelate_heatmap_result1.png test-data/hicCorrelate_scatter_result1.png test-data/hicDifferentialTAD/accepted.txt test-data/hicDifferentialTAD/rejected.txt test-data/hicHyperoptDetectLoops/loops.bedgraph test-data/hicInfo/hicInfo_output.txt test-data/hicInterIntraTAD/matrix.cool test-data/hicInterIntraTAD/output.txt test-data/hicMergeDomains/ctcf_plot/two_files_plot_1.pdf test-data/hicPlotAverageRegions/defaults.png test-data/hicPlotAverageRegions/defaults_log.png test-data/hicPlotAverageRegions/defaults_log1p.png test-data/hicPlotAverageRegions/defaults_log_vmin_vmax.png test-data/hicPlotMatrix/plot1.png test-data/hicPlotMatrix/plot2.pdf test-data/hicPlotMatrix/plot3_pca.svg test-data/hicPlotSVL/p_values.txt test-data/hicPlotSVL/plot.png test-data/hicPlotSVL/ratios.txt test-data/hicQuickQC/QC.log test-data/hicTADClassifier/predicted.txt test-data/hicTADClassifier/predicted_second_classifier.txt test-data/hicTADClassifier/unittest_classifier.BIN test-data/hicTrainTADClassifier/model.BIN test-data/hicTrainTADClassifier/multiFDR_dekker_domains.bed test-data/hicTrainTADClassifier/small_test_matrix.cool test-data/hicValidateLocations/overlap_smc3_statistics test-data/li_viewpoint_32-33Mb.png test-data/li_viewpoint_32Mb.png test-data/small_test_matrix_result_sorted.bam
diffstat 37 files changed, 666 insertions(+), 667 deletions(-) [+]
line wrap: on
line diff
--- a/macros.xml	Wed Oct 18 10:44:35 2023 +0000
+++ b/macros.xml	Mon Jul 01 20:12:19 2024 +0000
@@ -1,7 +1,8 @@
 <macros>
     <token name="@THREADS@">\${GALAXY_SLOTS:-4}</token>
-    <token name="@TOOL_VERSION@">3.7.2</token>
+    <token name="@TOOL_VERSION@">3.7.5</token>
     <token name="@VERSION_SUFFIX@">0</token>
+    <token name="@PROFILE@">23.0</token>
     <token name="@USE_RANGE@">
         #if $use_range.select_use_range == "yes_use_range":
             --range $use_range.range_min:$use_range.range_max
@@ -248,7 +249,7 @@
         #set $matrices = []
         #set $mlabels = []
         #for $counter, $i in enumerate($input_files):
-            ln -s '$i.matrix' '${counter}_matrix.$i.matrix.ext'; 
+            ln -s '$i.matrix' '${counter}_matrix.$i.matrix.ext';
             #silent $matrices.append( '\'%s_matrix.%s\'' % ($counter,  $i.matrix.ext))
 
             #if str($i.mlabel.value) != "":
Binary file test-data/cHi-C/chicExportData/aggregate.tar.gz has changed
Binary file test-data/cHi-C/chicQualityControl/histogram.png has changed
--- a/test-data/cHi-C/chicQualityControl/new_referencepoints.bed_raw_filter	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/cHi-C/chicQualityControl/new_referencepoints.bed_raw_filter	Mon Jul 01 20:12:19 2024 +0000
@@ -1,4 +1,4 @@
-# Created with chicQualityControl version 3.7.2
+# Created with chicQualityControl version 3.7.5
 # A sparsity of -1.0 indicates a faulty reference point e.g. no data for this reference point was in the matrix.
 # Used Matrices 0_matrix.cool	1_matrix.cool	
 # Chromosome	Start	End	Sparsity 0_matrix.cool	Sparsity 1_matrix.cool
--- a/test-data/cHi-C/chicQualityControl/new_referencepoints.bed_report	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/cHi-C/chicQualityControl/new_referencepoints.bed_report	Mon Jul 01 20:12:19 2024 +0000
@@ -1,4 +1,4 @@
-# Created with chicQualityControl version 3.7.2
+# Created with chicQualityControl version 3.7.5
 # QC report for matrices: 0_matrix.cool 1_matrix.cool 
 #Sparsity threshold for rejection: sparsity <= 0.05 are rejected.
 
Binary file test-data/cHi-C/chicQualityControl/sparsity.png has changed
Binary file test-data/cHi-C/plots.tar.gz has changed
--- a/test-data/cHi-C/target_list.bed	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/cHi-C/target_list.bed	Mon Jul 01 20:12:19 2024 +0000
@@ -1,8 +1,8 @@
-chr1    4480000 4549000
-chr1    4555000 4688000
-chr1    14274000    14279000
-chr1    14290000    14439000
-chr1    14444000    14467000
-chr1    14476000    14501000
-chr1    19077000    19118000
-chr1    19120000    19274000
\ No newline at end of file
+chr1	4480000	4549000
+chr1	4555000	4688000
+chr1	14274000	14279000
+chr1	14290000	14439000
+chr1	14444000	14467000
+chr1	14476000	14501000
+chr1	19077000	19118000
+chr1	19120000	19274000
Binary file test-data/hicAggregateContacts_results1.png has changed
Binary file test-data/hicCorrectMatrix/diagnostic_plot.png has changed
Binary file test-data/hicCorrelate_heatmap_result1.png has changed
Binary file test-data/hicCorrelate_scatter_result1.png has changed
--- a/test-data/hicDifferentialTAD/accepted.txt	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicDifferentialTAD/accepted.txt	Mon Jul 01 20:12:19 2024 +0000
@@ -1,4 +1,4 @@
-# Created with HiCExplorer's hicDifferentialTAD version 3.7.2
+# Created with HiCExplorer's hicDifferentialTAD version 3.7.5
 # H0 'regions are equal' H0 is accepted for all p-value greater the user given p-value threshold; i.e. regions in this file are not considered as differential.
 # Accepted regions with Wilcoxon rank-sum test to p-value: 1.0  with used mode: all and modeReject: one 
 # Chromosome	start	end	name	score	strand	p-value left-inter-TAD	p-value right-inter-TAD	p-value intra-TAD	W left-inter-TAD	W right-inter-TAD	W intra-TAD
--- a/test-data/hicDifferentialTAD/rejected.txt	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicDifferentialTAD/rejected.txt	Mon Jul 01 20:12:19 2024 +0000
@@ -1,4 +1,4 @@
-# Created with HiCExplorer's hicDifferentialTAD version 3.7.2
+# Created with HiCExplorer's hicDifferentialTAD version 3.7.5
 # H0 'regions are equal' H0 is rejected for all p-value smaller or equal the user given p-value threshold; i.e. regions in this file are considered as differential.
 # Rejected regions with Wilcoxon rank-sum test to p-value: 1.0  with used mode: all and modeReject: one 
 # Chromosome	start	end	name	score	strand	p-value left-inter-TAD	p-value right-inter-TAD	p-value intra-TAD	W left-inter-TAD	W right-inter-TAD	W intra-TAD
--- a/test-data/hicHyperoptDetectLoops/loops.bedgraph	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicHyperoptDetectLoops/loops.bedgraph	Mon Jul 01 20:12:19 2024 +0000
@@ -1,3 +1,3 @@
-# Created by HiCExplorer hicHyperoptDetectLoops 3.6
+# Created by HiCExplorer hicHyperoptDetectLoops 3.7.3
 
-{'matrixFile': 'matrix.cool', 'maxLoopDistance': 2600000, 'maximumNumberOfLoops': 5, 'oet': 4.594451600287669, 'p': 0.07561093779253786, 'peakWidth': 2, 'pit': 68.07931954714506, 'pp': 0.021875258449572325, 'proteinFile': 'hicValidateLocations/GSM935376_hg19_Gm12878_Smc3.narrowPeak', 'resolution': 2, 'threads': 1, 'windowSize': 10}
\ No newline at end of file
+{'chrPrefixLoops': None, 'matrixFile': 'matrix.cool', 'maxLoopDistance': 2300000, 'maximumNumberOfLoops': 5, 'oet': 1.230889168935347, 'p': 0.048940366161874596, 'peakWidth': 6, 'pit': 22.88867979095296, 'pp': 0.13365961880597724, 'proteinFile': '/tmp/tmpjkr0wi60/files/6/a/7/dataset_6a78c4eb-7f74-459b-9ed8-08972cc0c5f4.dat', 'resolution': 2, 'threads': 1, 'windowSize': 6}
\ No newline at end of file
--- a/test-data/hicInfo/hicInfo_output.txt	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicInfo/hicInfo_output.txt	Mon Jul 01 20:12:19 2024 +0000
@@ -1,4 +1,4 @@
-# Matrix information file. Created with HiCExplorer's hicInfo version 3.7.2
+# Matrix information file. Created with HiCExplorer's hicInfo version 3.7.5
 File:	matrix_name.h5
 Size:	33,754
 Bin_length:	5000
Binary file test-data/hicInterIntraTAD/matrix.cool has changed
--- a/test-data/hicInterIntraTAD/output.txt	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicInterIntraTAD/output.txt	Mon Jul 01 20:12:19 2024 +0000
@@ -1,22 +1,22 @@
-# Created with HiCExplorer's hicInterIntraTAD version 3.7.2
+# Created with HiCExplorer's hicInterIntraTAD version 3.7.5
 # Chromosome	start	end	name	score	strand	inter_left_sum	inter_right_sum	inter_left_density	inter_right_density	inter_left_number_of_contacts	inter_right_number_of_contacts	inter_left_number_of_contacts_nnz	inter_right_number_of_contacts_nnz	intra_sum	intra_number_of_contacts	intra_number_of_contacts_nnz	intra_density	inter_left_intra_ratio	inter_right_intra_ratio	inter_left_inter_right_intra_ratio
-chr2	17100000	18100000	region_0	0	+	0	148.64980341892507	0	1.0	0	90	0	90	289.00804022517053	100	100	1.0	0.0	0.5143448718696884	0.5143448718696884
-chr2	18100000	19100000	region_1	0	+	162.1124908492847	211.04026046280666	1.0	1.0	100	140	100	140	277.9356647725957	100	100	1.0	0.583273438412172	0.7593133491359512	1.3425867875481232
-chr2	19100000	20600000	region_2	0	+	223.14353637851622	150.01947633135822	1.0	1.0	150	90	150	90	556.143932925097	225	225	1.0	0.4012334274777925	0.269749371430369	0.6709827989081616
-chr2	20600000	21300000	region_3	0	+	171.34866125986417	274.4679914622871	1.0	1.0	105	84	105	84	149.85761183392816	49	49	1.0	1.1434097952244984	1.8315251931710472	2.9749349883955456
-chr2	21300000	22600000	region_4	0	+	283.89289960594425	768.874984677404	1.0	1.0	91	208	91	208	24180.36424789467	169	169	1.0	0.011740637845464306	0.03179749390021485	0.04353813174567915
-chr2	22600000	24300000	region_5	0	+	789.804014201572	321.70053830625835	1.0	1.0	221	238	221	238	659.9593561049022	289	289	1.0	1.1967464464221198	0.48745507633219043	1.6842015227543101
-chr2	24300000	25800000	region_6	0	+	340.44705127228065	836.790681935677	1.0	1.0	255	720	255	720	598.8884085354028	225	225	1.0	0.5684649200422041	1.3972397361673277	1.965704656209532
-chr2	25800000	30700000	region_7	0	+	852.3657188383157	1593.0953595672838	1.0	1.0	735	1421	735	1421	4153.286346671477	2401	2401	1.0	0.20522681262307327	0.3835746506724779	0.5888014632955512
-chr2	30700000	33700000	region_8	0	+	1644.3620053137968	315.02407146145276	1.0	1.0	1470	240	1470	240	1873.0714290428866	900	900	1.0	0.8778960480722525	0.16818582920910052	1.046081877281353
-chr2	33700000	34600000	region_9	0	+	351.38600814451206	204.32883091037917	1.0	1.0	270	153	270	153	245.00889544594847	81	81	1.0	1.434176532672184	0.8339649486541041	2.268141481326288
-chr2	34600000	36400000	region_10	0	+	213.88883777381795	379.5343566721307	1.0	1.0	162	288	162	288	770.6376988509402	324	324	1.0	0.27754785172427593	0.49249388816305717	0.7700417398873332
-chr2	36400000	38100000	region_11	0	+	399.4783208321819	189.4340956757372	1.0	1.0	306	136	306	136	635.9658356069232	289	289	1.0	0.6281443097504547	0.29786835246417603	0.9260126622146307
-chr2	38100000	39000000	region_12	0	+	209.82145375215833	74.59004956153072	1.0	1.0	153	45	153	45	229.67774089590498	81	81	1.0	0.9135471854334115	0.3247595925951596	1.2383067780285713
-chr2	39000000	39600000	region_13	0	+	87.2296637584025	120.04828267162685	1.0	1.0	54	72	54	72	114.2377217834551	36	36	1.0	0.7635802114799864	1.0508637672168046	1.814443978696791
-chr2	39600000	40900000	region_14	0	+	127.68593516818584	348.8073054441913	1.0	1.0	78	247	78	247	447.58733970743407	169	169	1.0	0.2852760206569915	0.7793055667575172	1.0645815874145086
-chr2	40900000	42900000	region_15	0	+	363.6155543954171	330.73139298156053	1.0	1.0	260	240	260	240	912.1015373488856	400	400	1.0	0.3986568813953566	0.3626037008367121	0.7612605822320687
-chr2	42900000	44200000	region_16	0	+	353.76150800590995	305.3562724757596	1.0	1.0	260	208	260	208	434.0150296605763	169	169	1.0	0.8150904550069866	0.7035615165552332	1.51865197156222
-chr2	44200000	45900000	region_17	0	+	321.3851510623236	309.7368872510572	1.0	1.0	221	221	221	221	667.4121186463332	289	289	1.0	0.4815392799791639	0.4640863996885097	0.9456256796676736
-chr2	45900000	47300000	region_18	0	+	330.1441180225245	330.3028710611577	1.0	1.0	238	238	238	238	509.86032585858186	196	196	1.0	0.6475187444062777	0.6478301101481911	1.2953488545544687
-chr2	47300000	49100000	region_19	0	+	330.3028710611577	0	1.0	0	238	0	238	0	737.4495555644096	324	324	1.0	0.44789893568836614	0.0	0.44789893568836614
+chr2	17100000	18100000	ID_0.01_10	-0.230354	.	0	148.64979	0	1.0	0	90	0	90	289.00809	100	100	1.0	0.0	0.5143447368549441	0.5143447368549441
+chr2	18100000	19100000	ID_0.01_11	-0.5135365	.	162.11248	211.04027000000002	1.0	1.0	100	140	100	140	277.9356	100	100	1.0	0.5832735353081793	0.7593135604075189	1.3425870957156982
+chr2	19100000	20600000	ID_0.01_12	-0.4202525	.	223.14355000000003	150.01946	1.0	1.0	150	90	150	90	556.14405	225	225	1.0	0.4012333675061345	0.2697492852795962	0.6709826527857307
+chr2	20600000	21300000	ID_0.01_13	-0.9980865	.	171.34865000000002	274.46791	1.0	1.0	105	84	105	84	149.85761000000002	49	49	1.0	1.1434097340802378	1.8315246719869613	2.974934406067199
+chr2	21300000	22600000	ID_0.01_14	-0.859866	.	283.89281	768.8750100000001	1.0	1.0	91	208	91	208	24180.409890000003	169	169	1.0	0.01174061197851762	0.031797434927601224	0.043538046906118844
+chr2	22600000	24300000	ID_0.01_15	-0.281294	.	789.8040400000002	321.70053	1.0	1.0	221	238	221	238	659.9594400000001	289	289	1.0	1.1967463333807304	0.48745500178010936	1.6842013351608398
+chr2	24300000	25800000	ID_0.01_16	-1.0366175	.	340.44703	836.7906700000001	1.0	1.0	255	720	255	720	598.88844	225	225	1.0	0.5684648546564032	1.397239642828972	1.9657044974853752
+chr2	25800000	30700000	ID_0.01_17	-0.1471245	.	852.3657199999999	1593.09544	1.0	1.0	735	1421	735	1421	4153.28651	2401	2401	1.0	0.205226804832205	0.38357465495439663	0.5888014597866016
+chr2	30700000	33700000	ID_0.01_18	-1.0134455	.	1644.36207	315.02405	1.0	1.0	1470	240	1470	240	1873.0712400000002	900	900	1.0	0.877896171210231	0.16818583472564555	1.0460820059358766
+chr2	33700000	34600000	ID_0.01_19	-1.33809	.	351.38599999999997	204.32889000000003	1.0	1.0	270	153	270	153	245.00895	81	81	1.0	1.4341761800946453	0.8339650041355633	2.268141184230209
+chr2	34600000	36400000	ID_0.01_20	-0.6325015	.	213.88889999999998	379.5344099999999	1.0	1.0	162	288	162	288	770.63772	324	324	1.0	0.27754792485371726	0.4924939438469219	0.7700418687006392
+chr2	36400000	38100000	ID_0.01_21	-0.925006	.	399.4784	189.43412	1.0	1.0	306	136	306	136	635.96573	289	289	1.0	0.6281445385429809	0.2978684401752277	0.9260129787182088
+chr2	38100000	39000000	ID_0.01_22	-0.911804	.	209.82147	74.59004	1.0	1.0	153	45	153	45	229.67774999999997	81	81	1.0	0.9135472199636231	0.3247595380919571	1.2383067580555802
+chr2	39000000	39600000	ID_0.01_23	-0.474157	.	87.22966	120.04826999999999	1.0	1.0	54	72	54	72	114.23772	36	36	1.0	0.7635801905010009	1.05086367269935	1.8144438632003508
+chr2	39600000	40900000	ID_0.01_24	-0.483398	.	127.68592	348.8071999999999	1.0	1.0	78	247	78	247	447.58727999999996	169	169	1.0	0.28527602482358305	0.7793054351321154	1.0645814599556984
+chr2	40900000	42900000	ID_0.01_25	-0.7016145	.	363.61542999999995	330.73137999999994	1.0	1.0	260	240	260	240	912.1014799999999	400	400	1.0	0.3986567700778207	0.362603709403037	0.7612604794808577
+chr2	42900000	44200000	ID_0.01_26	-0.6584895	.	353.76149	305.35633	1.0	1.0	260	208	260	208	434.01493999999997	169	169	1.0	0.8150905819048533	0.7035617944396109	1.5186523763444641
+chr2	44200000	45900000	ID_0.01_27	-1.4067435	.	321.38521000000003	309.73695	1.0	1.0	221	221	221	221	667.4121100000001	289	289	1.0	0.4815393745252839	0.46408649971904153	0.9456258742443254
+chr2	45900000	47300000	ID_0.01_28	-0.656308	.	330.14417000000003	330.30287	1.0	1.0	238	238	238	238	509.86028	196	196	1.0	0.6475189045908814	0.647830166334981	1.2953490709258624
+chr2	47300000	49100000	ID_0.01_29	-0.0033885	.	330.30287	0	1.0	0	238	0	238	0	737.44951	324	324	1.0	0.4478989619235085	0.0	0.4478989619235085
Binary file test-data/hicMergeDomains/ctcf_plot/two_files_plot_1.pdf has changed
Binary file test-data/hicPlotAverageRegions/defaults.png has changed
Binary file test-data/hicPlotAverageRegions/defaults_log.png has changed
Binary file test-data/hicPlotAverageRegions/defaults_log1p.png has changed
Binary file test-data/hicPlotAverageRegions/defaults_log_vmin_vmax.png has changed
Binary file test-data/hicPlotMatrix/plot1.png has changed
Binary file test-data/hicPlotMatrix/plot2.pdf has changed
--- a/test-data/hicPlotMatrix/plot3_pca.svg	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicPlotMatrix/plot3_pca.svg	Mon Jul 01 20:12:19 2024 +0000
@@ -1,24 +1,23 @@
 <?xml version="1.0" encoding="utf-8" standalone="no"?>
 <!DOCTYPE svg PUBLIC "-//W3C//DTD SVG 1.1//EN"
   "http://www.w3.org/Graphics/SVG/1.1/DTD/svg11.dtd">
-<!-- Created with matplotlib (https://matplotlib.org/) -->
-<svg height="540pt" version="1.1" viewBox="0 0 612 540" width="612pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
+<svg xmlns:xlink="http://www.w3.org/1999/xlink" width="612pt" height="540pt" viewBox="0 0 612 540" xmlns="http://www.w3.org/2000/svg" version="1.1">
  <metadata>
-  <rdf:RDF xmlns:cc="http://creativecommons.org/ns#" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
+  <rdf:RDF xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:cc="http://creativecommons.org/ns#" xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#">
    <cc:Work>
     <dc:type rdf:resource="http://purl.org/dc/dcmitype/StillImage"/>
-    <dc:date>2021-10-21T12:01:15.926583</dc:date>
+    <dc:date>2024-02-11T14:04:07.014551</dc:date>
     <dc:format>image/svg+xml</dc:format>
     <dc:creator>
      <cc:Agent>
-      <dc:title>Matplotlib v3.3.2, https://matplotlib.org/</dc:title>
+      <dc:title>Matplotlib v3.6.2, https://matplotlib.org/</dc:title>
      </cc:Agent>
     </dc:creator>
    </cc:Work>
   </rdf:RDF>
  </metadata>
  <defs>
-  <style type="text/css">*{stroke-linecap:butt;stroke-linejoin:round;}</style>
+  <style type="text/css">*{stroke-linejoin: round; stroke-linecap: butt}</style>
  </defs>
  <g id="figure_1">
   <g id="patch_1">
@@ -27,7 +26,7 @@
 L 612 0 
 L 0 0 
 z
-" style="fill:#ffffff;"/>
+" style="fill: #ffffff"/>
   </g>
   <g id="axes_1">
    <g id="patch_2">
@@ -36,367 +35,375 @@
 L 525.2375 36.3125 
 L 71.4125 36.3125 
 z
-" style="fill:#ffffff;"/>
+" style="fill: #ffffff"/>
    </g>
-   <image height="410.4" id="imagef9750a749d" transform="scale(1 -1)translate(0 -410.4)" width="453.6" x="72" xlink:href="data:image/png;base64,
-iVBORw0KGgoAAAANSUhEUgAAAD8AAAA5CAYAAACBBvPCAAABHElEQVR4nO2azRLCIAyEg1d9RHw7H5E7njrjT6kEQxKa/Y4OKtslG9OarkSVgnKx3oAlEB8ViD8LJfNeT0j7oEB8VE4lfi/YWmFHhMBbm1LHvWOLPzpGJtzT8FvZ4m+P4e8S518jUPMrUbJc6cH5qEC8J7Z61mipLPHcDY0I2FqpRktlieduaG+9xgXsBWmvRa+Lv9ahzwsg5jzHjc+1VsPSFOdL9jUAtcCxjwrEa3J02+l1XNUIQdc1Pzs4XYufDWpeEunBZdnBxvuPHRz7qCDtJXD3GKsDkWd1pVZWsHm5UCLH3nuqt3hzftSRFYUTIfDiAvFRgXjuf1bPQjPtV+3dHNDqPGBRYl/irercosRw7Ge53fO5lh0ltPNPhL1dYvY75GkAAAAASUVORK5CYII=" y="-36"/>
+   <image xlink:href="data:image/png;base64,
+iVBORw0KGgoAAAANSUhEUgAAAD8AAAA5CAYAAACBBvPCAAABNUlEQVR4nO2ZwRKDIAxEo9f2E+3f9RO92xOO7aAlkBBi9h0ddVzZXQSnB9FGQZmtH8ASiI8KxN+FdeEdn9D2QYH4qNxKfK7YzsqOCIXnm3WrHzv34uk1VV/q0vYpx893231cipfCne3X5brBOWDkowLxmnDzmc6XyvUVLPE1Qo7TUcn16fzWaawEFF5UsuJL7a2Vy3/3VZ3nf7N6V7IjLyG8tuV7Upx5zsPVOMfCaWj7qKiKt8gxB9h+VLSdg5HvwYj5VxG/L0sP28rc1d3VeVIvUkX8LrRhW/nrPoXHucxE/S05yroBhRcVMfGt0bGYDWD7qEC8dt5G/LojEsq81z2/3fYto6MlHKs6RVB4Z4xaVFJgD8/6IaxA5o9w/8zUMEocWLb3+jFzBsv2SXivX8jahC68DyTZYHVMEGd/AAAAAElFTkSuQmCC" id="imagee9b55c69ef" transform="scale(1 -1) translate(0 -410.4)" x="72" y="-36" width="453.6" height="410.4"/>
    <g id="matplotlib.axis_1">
     <g id="xtick_1">
      <g id="line2d_1">
       <defs>
-       <path d="M 0 0 
+       <path id="m2f4bd1209e" d="M 0 0 
 L 0 -3.5 
-" id="mb5ef7c54c4" style="stroke:#000000;stroke-width:0.8;"/>
+" style="stroke: #000000; stroke-width: 0.8"/>
       </defs>
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#mb5ef7c54c4" y="36.3125"/>
+       <use xlink:href="#m2f4bd1209e" x="73.681625" y="36.3125" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_1">
       <!-- 3.00  -->
-      <g transform="translate(60.815178 27.58012)scale(0.0833 -0.0833)">
+      <g transform="translate(63.084303 27.58012) scale(0.0833 -0.0833)">
        <defs>
-        <path d="M 40.578125 39.3125 
-Q 47.65625 37.796875 51.625 33 
-Q 55.609375 28.21875 55.609375 21.1875 
-Q 55.609375 10.40625 48.1875 4.484375 
-Q 40.765625 -1.421875 27.09375 -1.421875 
-Q 22.515625 -1.421875 17.65625 -0.515625 
-Q 12.796875 0.390625 7.625 2.203125 
-L 7.625 11.71875 
-Q 11.71875 9.328125 16.59375 8.109375 
-Q 21.484375 6.890625 26.8125 6.890625 
-Q 36.078125 6.890625 40.9375 10.546875 
-Q 45.796875 14.203125 45.796875 21.1875 
-Q 45.796875 27.640625 41.28125 31.265625 
-Q 36.765625 34.90625 28.71875 34.90625 
-L 20.21875 34.90625 
-L 20.21875 43.015625 
-L 29.109375 43.015625 
-Q 36.375 43.015625 40.234375 45.921875 
-Q 44.09375 48.828125 44.09375 54.296875 
-Q 44.09375 59.90625 40.109375 62.90625 
-Q 36.140625 65.921875 28.71875 65.921875 
-Q 24.65625 65.921875 20.015625 65.03125 
-Q 15.375 64.15625 9.8125 62.3125 
-L 9.8125 71.09375 
-Q 15.4375 72.65625 20.34375 73.4375 
-Q 25.25 74.21875 29.59375 74.21875 
-Q 40.828125 74.21875 47.359375 69.109375 
-Q 53.90625 64.015625 53.90625 55.328125 
-Q 53.90625 49.265625 50.4375 45.09375 
-Q 46.96875 40.921875 40.578125 39.3125 
+        <path id="DejaVuSans-33" d="M 2597 2516 
+Q 3050 2419 3304 2112 
+Q 3559 1806 3559 1356 
+Q 3559 666 3084 287 
+Q 2609 -91 1734 -91 
+Q 1441 -91 1130 -33 
+Q 819 25 488 141 
+L 488 750 
+Q 750 597 1062 519 
+Q 1375 441 1716 441 
+Q 2309 441 2620 675 
+Q 2931 909 2931 1356 
+Q 2931 1769 2642 2001 
+Q 2353 2234 1838 2234 
+L 1294 2234 
+L 1294 2753 
+L 1863 2753 
+Q 2328 2753 2575 2939 
+Q 2822 3125 2822 3475 
+Q 2822 3834 2567 4026 
+Q 2313 4219 1838 4219 
+Q 1578 4219 1281 4162 
+Q 984 4106 628 3988 
+L 628 4550 
+Q 988 4650 1302 4700 
+Q 1616 4750 1894 4750 
+Q 2613 4750 3031 4423 
+Q 3450 4097 3450 3541 
+Q 3450 3153 3228 2886 
+Q 3006 2619 2597 2516 
 z
-" id="DejaVuSans-51"/>
-        <path d="M 10.6875 12.40625 
-L 21 12.40625 
-L 21 0 
-L 10.6875 0 
+" transform="scale(0.015625)"/>
+        <path id="DejaVuSans-2e" d="M 684 794 
+L 1344 794 
+L 1344 0 
+L 684 0 
+L 684 794 
 z
-" id="DejaVuSans-46"/>
-        <path d="M 31.78125 66.40625 
-Q 24.171875 66.40625 20.328125 58.90625 
-Q 16.5 51.421875 16.5 36.375 
-Q 16.5 21.390625 20.328125 13.890625 
-Q 24.171875 6.390625 31.78125 6.390625 
-Q 39.453125 6.390625 43.28125 13.890625 
-Q 47.125 21.390625 47.125 36.375 
-Q 47.125 51.421875 43.28125 58.90625 
-Q 39.453125 66.40625 31.78125 66.40625 
+" transform="scale(0.015625)"/>
+        <path id="DejaVuSans-30" d="M 2034 4250 
+Q 1547 4250 1301 3770 
+Q 1056 3291 1056 2328 
+Q 1056 1369 1301 889 
+Q 1547 409 2034 409 
+Q 2525 409 2770 889 
+Q 3016 1369 3016 2328 
+Q 3016 3291 2770 3770 
+Q 2525 4250 2034 4250 
 z
-M 31.78125 74.21875 
-Q 44.046875 74.21875 50.515625 64.515625 
-Q 56.984375 54.828125 56.984375 36.375 
-Q 56.984375 17.96875 50.515625 8.265625 
-Q 44.046875 -1.421875 31.78125 -1.421875 
-Q 19.53125 -1.421875 13.0625 8.265625 
-Q 6.59375 17.96875 6.59375 36.375 
-Q 6.59375 54.828125 13.0625 64.515625 
-Q 19.53125 74.21875 31.78125 74.21875 
+M 2034 4750 
+Q 2819 4750 3233 4129 
+Q 3647 3509 3647 2328 
+Q 3647 1150 3233 529 
+Q 2819 -91 2034 -91 
+Q 1250 -91 836 529 
+Q 422 1150 422 2328 
+Q 422 3509 836 4129 
+Q 1250 4750 2034 4750 
 z
-" id="DejaVuSans-48"/>
-        <path id="DejaVuSans-32"/>
+" transform="scale(0.015625)"/>
+        <path id="DejaVuSans-20" transform="scale(0.015625)"/>
        </defs>
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-48"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-30" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="xtick_2">
      <g id="line2d_2">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="163.094318" xlink:href="#mb5ef7c54c4" y="36.3125"/>
+       <use xlink:href="#m2f4bd1209e" x="164.446625" y="36.3125" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_2">
       <!-- 3.10  -->
-      <g transform="translate(152.496996 27.58012)scale(0.0833 -0.0833)">
+      <g transform="translate(153.849303 27.58012) scale(0.0833 -0.0833)">
        <defs>
-        <path d="M 12.40625 8.296875 
-L 28.515625 8.296875 
-L 28.515625 63.921875 
-L 10.984375 60.40625 
-L 10.984375 69.390625 
-L 28.421875 72.90625 
-L 38.28125 72.90625 
-L 38.28125 8.296875 
-L 54.390625 8.296875 
-L 54.390625 0 
-L 12.40625 0 
+        <path id="DejaVuSans-31" d="M 794 531 
+L 1825 531 
+L 1825 4091 
+L 703 3866 
+L 703 4441 
+L 1819 4666 
+L 2450 4666 
+L 2450 531 
+L 3481 531 
+L 3481 0 
+L 794 0 
+L 794 531 
 z
-" id="DejaVuSans-49"/>
+" transform="scale(0.015625)"/>
        </defs>
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-49"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-31" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="xtick_3">
      <g id="line2d_3">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="254.776136" xlink:href="#mb5ef7c54c4" y="36.3125"/>
+       <use xlink:href="#m2f4bd1209e" x="255.211625" y="36.3125" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_3">
       <!-- 3.20  -->
-      <g transform="translate(244.178814 27.58012)scale(0.0833 -0.0833)">
+      <g transform="translate(244.614303 27.58012) scale(0.0833 -0.0833)">
        <defs>
-        <path d="M 19.1875 8.296875 
-L 53.609375 8.296875 
-L 53.609375 0 
-L 7.328125 0 
-L 7.328125 8.296875 
-Q 12.9375 14.109375 22.625 23.890625 
-Q 32.328125 33.6875 34.8125 36.53125 
-Q 39.546875 41.84375 41.421875 45.53125 
-Q 43.3125 49.21875 43.3125 52.78125 
-Q 43.3125 58.59375 39.234375 62.25 
-Q 35.15625 65.921875 28.609375 65.921875 
-Q 23.96875 65.921875 18.8125 64.3125 
-Q 13.671875 62.703125 7.8125 59.421875 
-L 7.8125 69.390625 
-Q 13.765625 71.78125 18.9375 73 
-Q 24.125 74.21875 28.421875 74.21875 
-Q 39.75 74.21875 46.484375 68.546875 
-Q 53.21875 62.890625 53.21875 53.421875 
-Q 53.21875 48.921875 51.53125 44.890625 
-Q 49.859375 40.875 45.40625 35.40625 
-Q 44.1875 33.984375 37.640625 27.21875 
-Q 31.109375 20.453125 19.1875 8.296875 
+        <path id="DejaVuSans-32" d="M 1228 531 
+L 3431 531 
+L 3431 0 
+L 469 0 
+L 469 531 
+Q 828 903 1448 1529 
+Q 2069 2156 2228 2338 
+Q 2531 2678 2651 2914 
+Q 2772 3150 2772 3378 
+Q 2772 3750 2511 3984 
+Q 2250 4219 1831 4219 
+Q 1534 4219 1204 4116 
+Q 875 4013 500 3803 
+L 500 4441 
+Q 881 4594 1212 4672 
+Q 1544 4750 1819 4750 
+Q 2544 4750 2975 4387 
+Q 3406 4025 3406 3419 
+Q 3406 3131 3298 2873 
+Q 3191 2616 2906 2266 
+Q 2828 2175 2409 1742 
+Q 1991 1309 1228 531 
 z
-" id="DejaVuSans-50"/>
+" transform="scale(0.015625)"/>
        </defs>
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-50"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-32" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="xtick_4">
      <g id="line2d_4">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="346.457955" xlink:href="#mb5ef7c54c4" y="36.3125"/>
+       <use xlink:href="#m2f4bd1209e" x="345.976625" y="36.3125" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_4">
       <!-- 3.30  -->
-      <g transform="translate(335.860633 27.58012)scale(0.0833 -0.0833)">
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-51"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+      <g transform="translate(335.379303 27.58012) scale(0.0833 -0.0833)">
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-33" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="xtick_5">
      <g id="line2d_5">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="438.139773" xlink:href="#mb5ef7c54c4" y="36.3125"/>
+       <use xlink:href="#m2f4bd1209e" x="436.741625" y="36.3125" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_5">
       <!-- 3.40  Mbp -->
-      <g transform="translate(417.336899 27.58012)scale(0.0833 -0.0833)">
+      <g transform="translate(415.938752 27.58012) scale(0.0833 -0.0833)">
        <defs>
-        <path d="M 37.796875 64.3125 
-L 12.890625 25.390625 
-L 37.796875 25.390625 
+        <path id="DejaVuSans-34" d="M 2419 4116 
+L 825 1625 
+L 2419 1625 
+L 2419 4116 
 z
-M 35.203125 72.90625 
-L 47.609375 72.90625 
-L 47.609375 25.390625 
-L 58.015625 25.390625 
-L 58.015625 17.1875 
-L 47.609375 17.1875 
-L 47.609375 0 
-L 37.796875 0 
-L 37.796875 17.1875 
-L 4.890625 17.1875 
-L 4.890625 26.703125 
+M 2253 4666 
+L 3047 4666 
+L 3047 1625 
+L 3713 1625 
+L 3713 1100 
+L 3047 1100 
+L 3047 0 
+L 2419 0 
+L 2419 1100 
+L 313 1100 
+L 313 1709 
+L 2253 4666 
 z
-" id="DejaVuSans-52"/>
-        <path d="M 9.8125 72.90625 
-L 24.515625 72.90625 
-L 43.109375 23.296875 
-L 61.8125 72.90625 
-L 76.515625 72.90625 
-L 76.515625 0 
-L 66.890625 0 
-L 66.890625 64.015625 
-L 48.09375 14.015625 
-L 38.1875 14.015625 
-L 19.390625 64.015625 
-L 19.390625 0 
-L 9.8125 0 
+" transform="scale(0.015625)"/>
+        <path id="DejaVuSans-4d" d="M 628 4666 
+L 1569 4666 
+L 2759 1491 
+L 3956 4666 
+L 4897 4666 
+L 4897 0 
+L 4281 0 
+L 4281 4097 
+L 3078 897 
+L 2444 897 
+L 1241 4097 
+L 1241 0 
+L 628 0 
+L 628 4666 
 z
-" id="DejaVuSans-77"/>
-        <path d="M 48.6875 27.296875 
-Q 48.6875 37.203125 44.609375 42.84375 
-Q 40.53125 48.484375 33.40625 48.484375 
-Q 26.265625 48.484375 22.1875 42.84375 
-Q 18.109375 37.203125 18.109375 27.296875 
-Q 18.109375 17.390625 22.1875 11.75 
-Q 26.265625 6.109375 33.40625 6.109375 
-Q 40.53125 6.109375 44.609375 11.75 
-Q 48.6875 17.390625 48.6875 27.296875 
+" transform="scale(0.015625)"/>
+        <path id="DejaVuSans-62" d="M 3116 1747 
+Q 3116 2381 2855 2742 
+Q 2594 3103 2138 3103 
+Q 1681 3103 1420 2742 
+Q 1159 2381 1159 1747 
+Q 1159 1113 1420 752 
+Q 1681 391 2138 391 
+Q 2594 391 2855 752 
+Q 3116 1113 3116 1747 
 z
-M 18.109375 46.390625 
-Q 20.953125 51.265625 25.265625 53.625 
-Q 29.59375 56 35.59375 56 
-Q 45.5625 56 51.78125 48.09375 
-Q 58.015625 40.1875 58.015625 27.296875 
-Q 58.015625 14.40625 51.78125 6.484375 
-Q 45.5625 -1.421875 35.59375 -1.421875 
-Q 29.59375 -1.421875 25.265625 0.953125 
-Q 20.953125 3.328125 18.109375 8.203125 
-L 18.109375 0 
-L 9.078125 0 
-L 9.078125 75.984375 
-L 18.109375 75.984375 
+M 1159 2969 
+Q 1341 3281 1617 3432 
+Q 1894 3584 2278 3584 
+Q 2916 3584 3314 3078 
+Q 3713 2572 3713 1747 
+Q 3713 922 3314 415 
+Q 2916 -91 2278 -91 
+Q 1894 -91 1617 61 
+Q 1341 213 1159 525 
+L 1159 0 
+L 581 0 
+L 581 4863 
+L 1159 4863 
+L 1159 2969 
 z
-" id="DejaVuSans-98"/>
-        <path d="M 18.109375 8.203125 
-L 18.109375 -20.796875 
-L 9.078125 -20.796875 
-L 9.078125 54.6875 
-L 18.109375 54.6875 
-L 18.109375 46.390625 
-Q 20.953125 51.265625 25.265625 53.625 
-Q 29.59375 56 35.59375 56 
-Q 45.5625 56 51.78125 48.09375 
-Q 58.015625 40.1875 58.015625 27.296875 
-Q 58.015625 14.40625 51.78125 6.484375 
-Q 45.5625 -1.421875 35.59375 -1.421875 
-Q 29.59375 -1.421875 25.265625 0.953125 
-Q 20.953125 3.328125 18.109375 8.203125 
+" transform="scale(0.015625)"/>
+        <path id="DejaVuSans-70" d="M 1159 525 
+L 1159 -1331 
+L 581 -1331 
+L 581 3500 
+L 1159 3500 
+L 1159 2969 
+Q 1341 3281 1617 3432 
+Q 1894 3584 2278 3584 
+Q 2916 3584 3314 3078 
+Q 3713 2572 3713 1747 
+Q 3713 922 3314 415 
+Q 2916 -91 2278 -91 
+Q 1894 -91 1617 61 
+Q 1341 213 1159 525 
 z
-M 48.6875 27.296875 
-Q 48.6875 37.203125 44.609375 42.84375 
-Q 40.53125 48.484375 33.40625 48.484375 
-Q 26.265625 48.484375 22.1875 42.84375 
-Q 18.109375 37.203125 18.109375 27.296875 
-Q 18.109375 17.390625 22.1875 11.75 
-Q 26.265625 6.109375 33.40625 6.109375 
-Q 40.53125 6.109375 44.609375 11.75 
-Q 48.6875 17.390625 48.6875 27.296875 
+M 3116 1747 
+Q 3116 2381 2855 2742 
+Q 2594 3103 2138 3103 
+Q 1681 3103 1420 2742 
+Q 1159 2381 1159 1747 
+Q 1159 1113 1420 752 
+Q 1681 391 2138 391 
+Q 2594 391 2855 752 
+Q 3116 1113 3116 1747 
 z
-" id="DejaVuSans-112"/>
+" transform="scale(0.015625)"/>
        </defs>
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-52"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
-       <use x="254.443359" xlink:href="#DejaVuSans-32"/>
-       <use x="286.230469" xlink:href="#DejaVuSans-77"/>
-       <use x="372.509766" xlink:href="#DejaVuSans-98"/>
-       <use x="435.986328" xlink:href="#DejaVuSans-112"/>
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-34" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
+       <use xlink:href="#DejaVuSans-20" x="254.443359"/>
+       <use xlink:href="#DejaVuSans-4d" x="286.230469"/>
+       <use xlink:href="#DejaVuSans-62" x="372.509766"/>
+       <use xlink:href="#DejaVuSans-70" x="435.986328"/>
       </g>
      </g>
     </g>
     <g id="text_6">
      <!-- chr2L -->
-     <g transform="translate(284.384375 17.250622)scale(0.1 -0.1)">
+     <g transform="translate(284.384375 17.250622) scale(0.1 -0.1)">
       <defs>
-       <path d="M 48.78125 52.59375 
-L 48.78125 44.1875 
-Q 44.96875 46.296875 41.140625 47.34375 
-Q 37.3125 48.390625 33.40625 48.390625 
-Q 24.65625 48.390625 19.8125 42.84375 
-Q 14.984375 37.3125 14.984375 27.296875 
-Q 14.984375 17.28125 19.8125 11.734375 
-Q 24.65625 6.203125 33.40625 6.203125 
-Q 37.3125 6.203125 41.140625 7.25 
-Q 44.96875 8.296875 48.78125 10.40625 
-L 48.78125 2.09375 
-Q 45.015625 0.34375 40.984375 -0.53125 
-Q 36.96875 -1.421875 32.421875 -1.421875 
-Q 20.0625 -1.421875 12.78125 6.34375 
-Q 5.515625 14.109375 5.515625 27.296875 
-Q 5.515625 40.671875 12.859375 48.328125 
-Q 20.21875 56 33.015625 56 
-Q 37.15625 56 41.109375 55.140625 
-Q 45.0625 54.296875 48.78125 52.59375 
+       <path id="DejaVuSans-63" d="M 3122 3366 
+L 3122 2828 
+Q 2878 2963 2633 3030 
+Q 2388 3097 2138 3097 
+Q 1578 3097 1268 2742 
+Q 959 2388 959 1747 
+Q 959 1106 1268 751 
+Q 1578 397 2138 397 
+Q 2388 397 2633 464 
+Q 2878 531 3122 666 
+L 3122 134 
+Q 2881 22 2623 -34 
+Q 2366 -91 2075 -91 
+Q 1284 -91 818 406 
+Q 353 903 353 1747 
+Q 353 2603 823 3093 
+Q 1294 3584 2113 3584 
+Q 2378 3584 2631 3529 
+Q 2884 3475 3122 3366 
 z
-" id="DejaVuSans-99"/>
-       <path d="M 54.890625 33.015625 
-L 54.890625 0 
-L 45.90625 0 
-L 45.90625 32.71875 
-Q 45.90625 40.484375 42.875 44.328125 
-Q 39.84375 48.1875 33.796875 48.1875 
-Q 26.515625 48.1875 22.3125 43.546875 
-Q 18.109375 38.921875 18.109375 30.90625 
-L 18.109375 0 
-L 9.078125 0 
-L 9.078125 75.984375 
-L 18.109375 75.984375 
-L 18.109375 46.1875 
-Q 21.34375 51.125 25.703125 53.5625 
-Q 30.078125 56 35.796875 56 
-Q 45.21875 56 50.046875 50.171875 
-Q 54.890625 44.34375 54.890625 33.015625 
+" transform="scale(0.015625)"/>
+       <path id="DejaVuSans-68" d="M 3513 2113 
+L 3513 0 
+L 2938 0 
+L 2938 2094 
+Q 2938 2591 2744 2837 
+Q 2550 3084 2163 3084 
+Q 1697 3084 1428 2787 
+Q 1159 2491 1159 1978 
+L 1159 0 
+L 581 0 
+L 581 4863 
+L 1159 4863 
+L 1159 2956 
+Q 1366 3272 1645 3428 
+Q 1925 3584 2291 3584 
+Q 2894 3584 3203 3211 
+Q 3513 2838 3513 2113 
 z
-" id="DejaVuSans-104"/>
-       <path d="M 41.109375 46.296875 
-Q 39.59375 47.171875 37.8125 47.578125 
-Q 36.03125 48 33.890625 48 
-Q 26.265625 48 22.1875 43.046875 
-Q 18.109375 38.09375 18.109375 28.8125 
-L 18.109375 0 
-L 9.078125 0 
-L 9.078125 54.6875 
-L 18.109375 54.6875 
-L 18.109375 46.1875 
-Q 20.953125 51.171875 25.484375 53.578125 
-Q 30.03125 56 36.53125 56 
-Q 37.453125 56 38.578125 55.875 
-Q 39.703125 55.765625 41.0625 55.515625 
+" transform="scale(0.015625)"/>
+       <path id="DejaVuSans-72" d="M 2631 2963 
+Q 2534 3019 2420 3045 
+Q 2306 3072 2169 3072 
+Q 1681 3072 1420 2755 
+Q 1159 2438 1159 1844 
+L 1159 0 
+L 581 0 
+L 581 3500 
+L 1159 3500 
+L 1159 2956 
+Q 1341 3275 1631 3429 
+Q 1922 3584 2338 3584 
+Q 2397 3584 2469 3576 
+Q 2541 3569 2628 3553 
+L 2631 2963 
 z
-" id="DejaVuSans-114"/>
-       <path d="M 9.8125 72.90625 
-L 19.671875 72.90625 
-L 19.671875 8.296875 
-L 55.171875 8.296875 
-L 55.171875 0 
-L 9.8125 0 
+" transform="scale(0.015625)"/>
+       <path id="DejaVuSans-4c" d="M 628 4666 
+L 1259 4666 
+L 1259 531 
+L 3531 531 
+L 3531 0 
+L 628 0 
+L 628 4666 
 z
-" id="DejaVuSans-76"/>
+" transform="scale(0.015625)"/>
       </defs>
-      <use xlink:href="#DejaVuSans-99"/>
-      <use x="54.980469" xlink:href="#DejaVuSans-104"/>
-      <use x="118.359375" xlink:href="#DejaVuSans-114"/>
-      <use x="159.472656" xlink:href="#DejaVuSans-50"/>
-      <use x="223.095703" xlink:href="#DejaVuSans-76"/>
+      <use xlink:href="#DejaVuSans-63"/>
+      <use xlink:href="#DejaVuSans-68" x="54.980469"/>
+      <use xlink:href="#DejaVuSans-72" x="118.359375"/>
+      <use xlink:href="#DejaVuSans-32" x="159.472656"/>
+      <use xlink:href="#DejaVuSans-4c" x="223.095703"/>
      </g>
     </g>
    </g>
@@ -404,447 +411,401 @@
     <g id="ytick_1">
      <g id="line2d_6">
       <defs>
-       <path d="M 0 0 
+       <path id="m116929dbf3" d="M 0 0 
 L -3.5 0 
-" id="m007817c1d4" style="stroke:#000000;stroke-width:0.8;"/>
+" style="stroke: #000000; stroke-width: 0.8"/>
       </defs>
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="36.3125"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="38.351399" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_7">
       <!-- 3.00  -->
-      <g transform="translate(43.217856 39.477249)scale(0.0833 -0.0833)">
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-48"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+      <g transform="translate(43.217856 41.516148) scale(0.0833 -0.0833)">
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-30" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="ytick_2">
      <g id="line2d_7">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="118.692242"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="119.907343" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_8">
       <!-- 3.10  -->
-      <g transform="translate(43.217856 121.856991)scale(0.0833 -0.0833)">
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-49"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+      <g transform="translate(43.217856 123.072093) scale(0.0833 -0.0833)">
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-31" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="ytick_3">
      <g id="line2d_8">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="201.071985"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="201.463288" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_9">
       <!-- 3.20  -->
-      <g transform="translate(43.217856 204.236734)scale(0.0833 -0.0833)">
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-50"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+      <g transform="translate(43.217856 204.628038) scale(0.0833 -0.0833)">
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-32" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="ytick_4">
      <g id="line2d_9">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="283.451727"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="283.019233" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_10">
       <!-- 3.30  -->
-      <g transform="translate(43.217856 286.616476)scale(0.0833 -0.0833)">
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-51"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
+      <g transform="translate(43.217856 286.183982) scale(0.0833 -0.0833)">
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-33" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
       </g>
      </g>
     </g>
     <g id="ytick_5">
      <g id="line2d_10">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="365.831469"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="364.575178" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_11">
       <!-- 3.40  Mbp -->
-      <g transform="translate(22.806753 368.996218)scale(0.0833 -0.0833)">
-       <use xlink:href="#DejaVuSans-51"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-52"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
-       <use x="222.65625" xlink:href="#DejaVuSans-32"/>
-       <use x="254.443359" xlink:href="#DejaVuSans-32"/>
-       <use x="286.230469" xlink:href="#DejaVuSans-77"/>
-       <use x="372.509766" xlink:href="#DejaVuSans-98"/>
-       <use x="435.986328" xlink:href="#DejaVuSans-112"/>
+      <g transform="translate(22.806753 367.739927) scale(0.0833 -0.0833)">
+       <use xlink:href="#DejaVuSans-33"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-34" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
+       <use xlink:href="#DejaVuSans-20" x="222.65625"/>
+       <use xlink:href="#DejaVuSans-20" x="254.443359"/>
+       <use xlink:href="#DejaVuSans-4d" x="286.230469"/>
+       <use xlink:href="#DejaVuSans-62" x="372.509766"/>
+       <use xlink:href="#DejaVuSans-70" x="435.986328"/>
       </g>
      </g>
     </g>
     <g id="text_12">
      <!-- chr2L -->
-     <g transform="translate(16.727066 254.142987)rotate(-90)scale(0.1 -0.1)">
-      <use xlink:href="#DejaVuSans-99"/>
-      <use x="54.980469" xlink:href="#DejaVuSans-104"/>
-      <use x="118.359375" xlink:href="#DejaVuSans-114"/>
-      <use x="159.472656" xlink:href="#DejaVuSans-50"/>
-      <use x="223.095703" xlink:href="#DejaVuSans-76"/>
+     <g transform="translate(16.727066 254.142987) rotate(-90) scale(0.1 -0.1)">
+      <use xlink:href="#DejaVuSans-63"/>
+      <use xlink:href="#DejaVuSans-68" x="54.980469"/>
+      <use xlink:href="#DejaVuSans-72" x="118.359375"/>
+      <use xlink:href="#DejaVuSans-32" x="159.472656"/>
+      <use xlink:href="#DejaVuSans-4c" x="223.095703"/>
      </g>
     </g>
    </g>
    <g id="patch_3">
     <path d="M 71.4125 444.092224 
 L 71.4125 36.3125 
-" style="fill:none;stroke:#000000;stroke-linecap:square;stroke-linejoin:miter;stroke-width:0.8;"/>
+" style="fill: none; stroke: #000000; stroke-width: 0.8; stroke-linejoin: miter; stroke-linecap: square"/>
    </g>
    <g id="patch_4">
     <path d="M 525.2375 444.092224 
 L 525.2375 36.3125 
-" style="fill:none;stroke:#000000;stroke-linecap:square;stroke-linejoin:miter;stroke-width:0.8;"/>
+" style="fill: none; stroke: #000000; stroke-width: 0.8; stroke-linejoin: miter; stroke-linecap: square"/>
    </g>
    <g id="patch_5">
     <path d="M 71.4125 444.092224 
 L 525.2375 444.092224 
-" style="fill:none;stroke:#000000;stroke-linecap:square;stroke-linejoin:miter;stroke-width:0.8;"/>
+" style="fill: none; stroke: #000000; stroke-width: 0.8; stroke-linejoin: miter; stroke-linecap: square"/>
    </g>
    <g id="patch_6">
     <path d="M 71.4125 36.3125 
 L 525.2375 36.3125 
-" style="fill:none;stroke:#000000;stroke-linecap:square;stroke-linejoin:miter;stroke-width:0.8;"/>
+" style="fill: none; stroke: #000000; stroke-width: 0.8; stroke-linejoin: miter; stroke-linecap: square"/>
    </g>
   </g>
   <g id="axes_2">
    <g id="patch_7">
-    <path clip-path="url(#p1d24998020)" d="M 536.0375 444.092224 
-L 536.0375 442.499335 
-L 536.0375 37.90539 
-L 536.0375 36.3125 
+    <path d="M 536.0375 444.092224 
+L 571.7 444.092224 
 L 571.7 36.3125 
-L 571.7 37.90539 
-L 571.7 442.499335 
-L 571.7 444.092224 
+L 536.0375 36.3125 
 z
-" style="fill:#ffffff;stroke:#ffffff;stroke-linejoin:miter;stroke-width:0.01;"/>
+" style="fill: #ffffff"/>
    </g>
-   <image height="410.4" id="imagef2d1b9e4d7" transform="scale(1 -1)translate(0 -410.4)" width="36" x="532.8" xlink:href="data:image/png;base64,
-iVBORw0KGgoAAAANSUhEUgAAAAUAAAA5CAYAAAD+1+EzAAAAcUlEQVR4nM2ROwqAQAxEJ5DKxQ/q/U9pY5Xt1ydEFsWUw2MmydgqhZrx0iqSfCQxTw5psjPojZU6PacsaQfUYUEdCeJdYOqC+BsSPeH4J+mdnj9cKftki5PajAJtagFPbSQiuZM4p8nPPJMXWURcvlQBuw0SeA+M4+4AAAAASUVORK5CYII=" y="-36"/>
+   <g id="patch_8">
+    <path clip-path="url(#p149ee43c70)" style="fill: #ffffff; stroke: #ffffff; stroke-width: 0.01; stroke-linejoin: miter"/>
+   </g>
+   <image xlink:href="data:image/png;base64,
+iVBORw0KGgoAAAANSUhEUgAAAAUAAAA5CAYAAAD+1+EzAAAAcElEQVR4nM2SOwqAQBBDM7A2ih/QwvtfUmyMvT5hYBHdMmRfAplYJevySntVJJWexC7tROaQdiLzh5Xq0mOHOcINbCSAFkH8gxPiq5nfpueDYOM3KoUPGi5m+K6RxIXEKe2sZGLPfHqSGfYGN2/fxBP5RRN8TCfhOwAAAABJRU5ErkJggg==" id="image0b883fc046" transform="scale(1 -1) translate(0 -410.4)" x="532.8" y="-36" width="36" height="410.4"/>
    <g id="matplotlib.axis_3"/>
    <g id="matplotlib.axis_4">
     <g id="ytick_6">
      <g id="line2d_11">
       <defs>
-       <path d="M 0 0 
+       <path id="m7b986001a8" d="M 0 0 
 L 3.5 0 
-" id="mc78e30fd90" style="stroke:#000000;stroke-width:0.8;"/>
+" style="stroke: #000000; stroke-width: 0.8"/>
       </defs>
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="444.092224"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="444.092224" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_13">
       <!-- 0.00 -->
-      <g transform="translate(578.7 447.891443)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-48"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-48"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
+      <g transform="translate(578.7 447.891443) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-30"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-30" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_7">
      <g id="line2d_12">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="393.119759"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="393.119759" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_14">
       <!-- 0.25 -->
-      <g transform="translate(578.7 396.918977)scale(0.1 -0.1)">
+      <g transform="translate(578.7 396.918977) scale(0.1 -0.1)">
        <defs>
-        <path d="M 10.796875 72.90625 
-L 49.515625 72.90625 
-L 49.515625 64.59375 
-L 19.828125 64.59375 
-L 19.828125 46.734375 
-Q 21.96875 47.46875 24.109375 47.828125 
-Q 26.265625 48.1875 28.421875 48.1875 
-Q 40.625 48.1875 47.75 41.5 
-Q 54.890625 34.8125 54.890625 23.390625 
-Q 54.890625 11.625 47.5625 5.09375 
-Q 40.234375 -1.421875 26.90625 -1.421875 
-Q 22.3125 -1.421875 17.546875 -0.640625 
-Q 12.796875 0.140625 7.71875 1.703125 
-L 7.71875 11.625 
-Q 12.109375 9.234375 16.796875 8.0625 
-Q 21.484375 6.890625 26.703125 6.890625 
-Q 35.15625 6.890625 40.078125 11.328125 
-Q 45.015625 15.765625 45.015625 23.390625 
-Q 45.015625 31 40.078125 35.4375 
-Q 35.15625 39.890625 26.703125 39.890625 
-Q 22.75 39.890625 18.8125 39.015625 
-Q 14.890625 38.140625 10.796875 36.28125 
+        <path id="DejaVuSans-35" d="M 691 4666 
+L 3169 4666 
+L 3169 4134 
+L 1269 4134 
+L 1269 2991 
+Q 1406 3038 1543 3061 
+Q 1681 3084 1819 3084 
+Q 2600 3084 3056 2656 
+Q 3513 2228 3513 1497 
+Q 3513 744 3044 326 
+Q 2575 -91 1722 -91 
+Q 1428 -91 1123 -41 
+Q 819 9 494 109 
+L 494 744 
+Q 775 591 1075 516 
+Q 1375 441 1709 441 
+Q 2250 441 2565 725 
+Q 2881 1009 2881 1497 
+Q 2881 1984 2565 2268 
+Q 2250 2553 1709 2553 
+Q 1456 2553 1204 2497 
+Q 953 2441 691 2322 
+L 691 4666 
 z
-" id="DejaVuSans-53"/>
+" transform="scale(0.015625)"/>
        </defs>
-       <use xlink:href="#DejaVuSans-48"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-50"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-53"/>
+       <use xlink:href="#DejaVuSans-30"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-32" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-35" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_8">
      <g id="line2d_13">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="342.147293"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="342.147293" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_15">
       <!-- 0.50 -->
-      <g transform="translate(578.7 345.946512)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-48"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-53"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
+      <g transform="translate(578.7 345.946512) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-30"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-35" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_9">
      <g id="line2d_14">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="291.174828"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="291.174828" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_16">
       <!-- 0.75 -->
-      <g transform="translate(578.7 294.974046)scale(0.1 -0.1)">
+      <g transform="translate(578.7 294.974046) scale(0.1 -0.1)">
        <defs>
-        <path d="M 8.203125 72.90625 
-L 55.078125 72.90625 
-L 55.078125 68.703125 
-L 28.609375 0 
-L 18.3125 0 
-L 43.21875 64.59375 
-L 8.203125 64.59375 
+        <path id="DejaVuSans-37" d="M 525 4666 
+L 3525 4666 
+L 3525 4397 
+L 1831 0 
+L 1172 0 
+L 2766 4134 
+L 525 4134 
+L 525 4666 
 z
-" id="DejaVuSans-55"/>
+" transform="scale(0.015625)"/>
        </defs>
-       <use xlink:href="#DejaVuSans-48"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-55"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-53"/>
+       <use xlink:href="#DejaVuSans-30"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-37" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-35" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_10">
      <g id="line2d_15">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="240.202362"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="240.202362" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_17">
       <!-- 1.00 -->
-      <g transform="translate(578.7 244.001581)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-49"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-48"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
+      <g transform="translate(578.7 244.001581) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-31"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-30" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_11">
      <g id="line2d_16">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="189.229897"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="189.229897" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_18">
       <!-- 1.25 -->
-      <g transform="translate(578.7 193.029115)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-49"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-50"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-53"/>
+      <g transform="translate(578.7 193.029115) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-31"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-32" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-35" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_12">
      <g id="line2d_17">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="138.257431"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="138.257431" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_19">
       <!-- 1.50 -->
-      <g transform="translate(578.7 142.05665)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-49"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-53"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
+      <g transform="translate(578.7 142.05665) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-31"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-35" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_13">
      <g id="line2d_18">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="87.284966"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="87.284966" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_20">
       <!-- 1.75 -->
-      <g transform="translate(578.7 91.084184)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-49"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-55"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-53"/>
+      <g transform="translate(578.7 91.084184) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-31"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-37" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-35" x="159.033203"/>
       </g>
      </g>
     </g>
     <g id="ytick_14">
      <g id="line2d_19">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="571.7" xlink:href="#mc78e30fd90" y="36.3125"/>
+       <use xlink:href="#m7b986001a8" x="571.7" y="36.3125" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_21">
       <!-- 2.00 -->
-      <g transform="translate(578.7 40.111719)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-50"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-46"/>
-       <use x="95.410156" xlink:href="#DejaVuSans-48"/>
-       <use x="159.033203" xlink:href="#DejaVuSans-48"/>
+      <g transform="translate(578.7 40.111719) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-32"/>
+       <use xlink:href="#DejaVuSans-2e" x="63.623047"/>
+       <use xlink:href="#DejaVuSans-30" x="95.410156"/>
+       <use xlink:href="#DejaVuSans-30" x="159.033203"/>
       </g>
      </g>
     </g>
    </g>
-   <g id="patch_8">
+   <g id="LineCollection_1"/>
+   <g id="patch_9">
     <path d="M 536.0375 444.092224 
-L 536.0375 442.499335 
-L 536.0375 37.90539 
-L 536.0375 36.3125 
+L 553.86875 444.092224 
+L 571.7 444.092224 
 L 571.7 36.3125 
-L 571.7 37.90539 
-L 571.7 442.499335 
-L 571.7 444.092224 
+L 553.86875 36.3125 
+L 536.0375 36.3125 
+L 536.0375 444.092224 
 z
-" style="fill:none;stroke:#000000;stroke-linejoin:miter;stroke-width:0.8;"/>
+" style="fill: none; stroke: #000000; stroke-width: 0.8; stroke-linejoin: miter; stroke-linecap: square"/>
    </g>
   </g>
   <g id="axes_3">
    <g id="PolyCollection_1">
-    <path clip-path="url(#pfb06fea9d9)" d="M 71.4125 461.675676 
+    <path d="M 71.4125 461.675676 
 L 71.4125 525.344717 
-L 71.4125 461.675676 
-L 71.4125 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 85.164773 461.675676 
+L 75.996591 525.344717 
+L 80.580682 525.344717 
 L 85.164773 525.344717 
 L 89.748864 525.344717 
-L 89.748864 461.675676 
-L 89.748864 461.675676 
-L 85.164773 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 103.501136 461.675676 
+L 94.332955 525.344717 
+L 98.917045 525.344717 
 L 103.501136 525.344717 
 L 108.085227 525.344717 
-L 108.085227 461.675676 
-L 108.085227 461.675676 
-L 103.501136 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 121.8375 461.675676 
+L 112.669318 525.344717 
+L 117.253409 525.344717 
 L 121.8375 525.344717 
 L 126.421591 525.344717 
 L 131.005682 525.344717 
-L 131.005682 461.675676 
-L 131.005682 461.675676 
-L 126.421591 461.675676 
-L 121.8375 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 149.342045 461.675676 
+L 135.589773 525.344717 
+L 140.173864 525.344717 
+L 144.757955 525.344717 
 L 149.342045 525.344717 
 L 153.926136 525.344717 
-L 153.926136 461.675676 
-L 153.926136 461.675676 
-L 149.342045 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 167.678409 461.675676 
+L 158.510227 525.344717 
+L 163.094318 525.344717 
 L 167.678409 525.344717 
-L 167.678409 461.675676 
-L 167.678409 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 181.430682 461.675676 
+L 172.2625 525.344717 
+L 176.846591 525.344717 
 L 181.430682 525.344717 
-L 181.430682 461.675676 
-L 181.430682 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 195.182955 461.675676 
+L 186.014773 525.344717 
+L 190.598864 525.344717 
 L 195.182955 525.344717 
 L 199.767045 525.344717 
 L 204.351136 525.344717 
-L 204.351136 461.675676 
-L 204.351136 461.675676 
-L 199.767045 461.675676 
-L 195.182955 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 227.271591 461.675676 
+L 208.935227 525.344717 
+L 213.519318 525.344717 
+L 218.103409 525.344717 
+L 222.6875 525.344717 
 L 227.271591 525.344717 
-L 227.271591 461.675676 
-L 227.271591 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 241.023864 461.675676 
+L 231.855682 525.344717 
+L 236.439773 525.344717 
 L 241.023864 525.344717 
 L 245.607955 525.344717 
-L 245.607955 461.675676 
-L 245.607955 461.675676 
-L 241.023864 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 254.776136 461.675676 
+L 250.192045 525.344717 
 L 254.776136 525.344717 
-L 254.776136 461.675676 
-L 254.776136 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 263.944318 461.675676 
+L 259.360227 525.344717 
 L 263.944318 525.344717 
 L 268.528409 525.344717 
 L 273.1125 525.344717 
 L 277.696591 525.344717 
 L 282.280682 525.344717 
 L 286.864773 525.344717 
-L 286.864773 461.675676 
-L 286.864773 461.675676 
-L 282.280682 461.675676 
-L 277.696591 461.675676 
-L 273.1125 461.675676 
-L 268.528409 461.675676 
-L 263.944318 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 305.201136 461.675676 
+L 291.448864 525.344717 
+L 296.032955 525.344717 
+L 300.617045 525.344717 
 L 305.201136 525.344717 
 L 309.785227 525.344717 
 L 314.369318 525.344717 
@@ -854,7 +815,87 @@
 L 332.705682 525.344717 
 L 337.289773 525.344717 
 L 341.873864 525.344717 
-L 341.873864 461.675676 
+L 346.457955 525.344717 
+L 351.042045 525.344717 
+L 355.626136 525.344717 
+L 360.210227 525.344717 
+L 364.794318 525.344717 
+L 369.378409 525.344717 
+L 373.9625 525.344717 
+L 378.546591 525.344717 
+L 383.130682 525.344717 
+L 387.714773 525.344717 
+L 392.298864 525.344717 
+L 396.882955 525.344717 
+L 401.467045 525.344717 
+L 406.051136 525.344717 
+L 410.635227 525.344717 
+L 415.219318 525.344717 
+L 419.803409 525.344717 
+L 424.3875 525.344717 
+L 428.971591 525.344717 
+L 433.555682 525.344717 
+L 438.139773 525.344717 
+L 442.723864 525.344717 
+L 447.307955 525.344717 
+L 451.892045 525.344717 
+L 456.476136 525.344717 
+L 461.060227 525.344717 
+L 465.644318 525.344717 
+L 470.228409 525.344717 
+L 474.8125 525.344717 
+L 479.396591 525.344717 
+L 483.980682 525.344717 
+L 488.564773 525.344717 
+L 493.148864 525.344717 
+L 497.732955 525.344717 
+L 502.317045 525.344717 
+L 506.901136 525.344717 
+L 511.485227 525.344717 
+L 516.069318 525.344717 
+L 520.653409 525.344717 
+L 525.2375 525.344717 
+L 525.2375 461.675676 
+L 525.2375 461.675676 
+L 520.653409 461.675676 
+L 516.069318 461.675676 
+L 511.485227 461.675676 
+L 506.901136 461.675676 
+L 502.317045 461.675676 
+L 497.732955 461.675676 
+L 493.148864 461.675676 
+L 488.564773 461.675676 
+L 483.980682 461.675676 
+L 479.396591 461.675676 
+L 474.8125 461.675676 
+L 470.228409 461.675676 
+L 465.644318 461.675676 
+L 461.060227 461.675676 
+L 456.476136 461.675676 
+L 451.892045 461.675676 
+L 447.307955 461.675676 
+L 442.723864 461.675676 
+L 438.139773 461.675676 
+L 433.555682 461.675676 
+L 428.971591 461.675676 
+L 424.3875 461.675676 
+L 419.803409 461.675676 
+L 415.219318 461.675676 
+L 410.635227 461.675676 
+L 406.051136 461.675676 
+L 401.467045 461.675676 
+L 396.882955 461.675676 
+L 392.298864 461.675676 
+L 387.714773 461.675676 
+L 383.130682 461.675676 
+L 378.546591 461.675676 
+L 373.9625 461.675676 
+L 369.378409 461.675676 
+L 364.794318 461.675676 
+L 360.210227 461.675676 
+L 355.626136 461.675676 
+L 351.042045 461.675676 
+L 346.457955 461.675676 
 L 341.873864 461.675676 
 L 337.289773 461.675676 
 L 332.705682 461.675676 
@@ -864,115 +905,98 @@
 L 314.369318 461.675676 
 L 309.785227 461.675676 
 L 305.201136 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 351.042045 461.675676 
-L 351.042045 525.344717 
-L 355.626136 525.344717 
-L 360.210227 525.344717 
-L 364.794318 525.344717 
-L 369.378409 525.344717 
-L 369.378409 461.675676 
-L 369.378409 461.675676 
-L 364.794318 461.675676 
-L 360.210227 461.675676 
-L 355.626136 461.675676 
-L 351.042045 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 396.882955 461.675676 
-L 396.882955 525.344717 
-L 401.467045 525.344717 
-L 401.467045 461.675676 
-L 401.467045 461.675676 
-L 396.882955 461.675676 
+L 300.617045 461.675676 
+L 296.032955 461.675676 
+L 291.448864 461.675676 
+L 286.864773 461.675676 
+L 282.280682 461.675676 
+L 277.696591 461.675676 
+L 273.1125 461.675676 
+L 268.528409 461.675676 
+L 263.944318 461.675676 
+L 259.360227 461.675676 
+L 254.776136 461.675676 
+L 250.192045 461.675676 
+L 245.607955 461.675676 
+L 241.023864 461.675676 
+L 236.439773 461.675676 
+L 231.855682 461.675676 
+L 227.271591 461.675676 
+L 222.6875 461.675676 
+L 218.103409 461.675676 
+L 213.519318 461.675676 
+L 208.935227 461.675676 
+L 204.351136 461.675676 
+L 199.767045 461.675676 
+L 195.182955 461.675676 
+L 190.598864 461.675676 
+L 186.014773 461.675676 
+L 181.430682 461.675676 
+L 176.846591 461.675676 
+L 172.2625 461.675676 
+L 167.678409 461.675676 
+L 163.094318 461.675676 
+L 158.510227 461.675676 
+L 153.926136 461.675676 
+L 149.342045 461.675676 
+L 144.757955 461.675676 
+L 140.173864 461.675676 
+L 135.589773 461.675676 
+L 131.005682 461.675676 
+L 126.421591 461.675676 
+L 121.8375 461.675676 
+L 117.253409 461.675676 
+L 112.669318 461.675676 
+L 108.085227 461.675676 
+L 103.501136 461.675676 
+L 98.917045 461.675676 
+L 94.332955 461.675676 
+L 89.748864 461.675676 
+L 85.164773 461.675676 
+L 80.580682 461.675676 
+L 75.996591 461.675676 
+L 71.4125 461.675676 
 z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 410.635227 461.675676 
-L 410.635227 525.344717 
-L 415.219318 525.344717 
-L 419.803409 525.344717 
-L 424.3875 525.344717 
-L 428.971591 525.344717 
-L 433.555682 525.344717 
-L 433.555682 461.675676 
-L 433.555682 461.675676 
-L 428.971591 461.675676 
-L 424.3875 461.675676 
-L 419.803409 461.675676 
-L 415.219318 461.675676 
-L 410.635227 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 442.723864 461.675676 
-L 442.723864 525.344717 
-L 447.307955 525.344717 
-L 447.307955 461.675676 
-L 447.307955 461.675676 
-L 442.723864 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 479.396591 461.675676 
-L 479.396591 525.344717 
-L 483.980682 525.344717 
-L 488.564773 525.344717 
-L 488.564773 461.675676 
-L 488.564773 461.675676 
-L 483.980682 461.675676 
-L 479.396591 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 497.732955 461.675676 
-L 497.732955 525.344717 
-L 497.732955 461.675676 
-L 497.732955 461.675676 
-z
-" style="fill:#1f77b4;"/>
-    <path clip-path="url(#pfb06fea9d9)" d="M 525.2375 461.675676 
-L 525.2375 525.344717 
-L 525.2375 461.675676 
-L 525.2375 461.675676 
-z
-" style="fill:#1f77b4;"/>
+" clip-path="url(#p13ffe222dd)" style="fill: #1f77b4"/>
    </g>
    <g id="matplotlib.axis_5">
     <g id="ytick_15">
      <g id="line2d_20">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="525.344717"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="525.344717" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_22">
       <!-- 0 -->
-      <g transform="translate(58.05 529.143936)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-48"/>
+      <g transform="translate(58.05 529.143936) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-30"/>
       </g>
      </g>
     </g>
     <g id="ytick_16">
      <g id="line2d_21">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="493.510197"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="493.510197" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_23">
       <!-- 5 -->
-      <g transform="translate(58.05 497.309415)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-53"/>
+      <g transform="translate(58.05 497.309415) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-35"/>
       </g>
      </g>
     </g>
     <g id="ytick_17">
      <g id="line2d_22">
       <g>
-       <use style="stroke:#000000;stroke-width:0.8;" x="71.4125" xlink:href="#m007817c1d4" y="461.675676"/>
+       <use xlink:href="#m116929dbf3" x="71.4125" y="461.675676" style="stroke: #000000; stroke-width: 0.8"/>
       </g>
      </g>
      <g id="text_24">
       <!-- 10 -->
-      <g transform="translate(51.6875 465.474895)scale(0.1 -0.1)">
-       <use xlink:href="#DejaVuSans-49"/>
-       <use x="63.623047" xlink:href="#DejaVuSans-48"/>
+      <g transform="translate(51.6875 465.474895) scale(0.1 -0.1)">
+       <use xlink:href="#DejaVuSans-31"/>
+       <use xlink:href="#DejaVuSans-30" x="63.623047"/>
       </g>
      </g>
     </g>
@@ -980,11 +1004,11 @@
   </g>
  </g>
  <defs>
-  <clipPath id="p1d24998020">
-   <rect height="407.779724" width="35.6625" x="536.0375" y="36.3125"/>
+  <clipPath id="p149ee43c70">
+   <rect x="536.0375" y="36.3125" width="35.6625" height="407.779724"/>
   </clipPath>
-  <clipPath id="pfb06fea9d9">
-   <rect height="70.035945" width="453.825" x="71.4125" y="458.492224"/>
+  <clipPath id="p13ffe222dd">
+   <rect x="71.4125" y="458.492224" width="453.825" height="70.035945"/>
   </clipPath>
  </defs>
 </svg>
--- a/test-data/hicPlotSVL/p_values.txt	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicPlotSVL/p_values.txt	Mon Jul 01 20:12:19 2024 +0000
@@ -1,4 +1,4 @@
-# Created with HiCExplorer's hicPlotSVL 3.7.2
+# Created with HiCExplorer's hicPlotSVL 3.7.5
 # Short range vs long range contacts per chromosome, p-values of each distribution against each other distribution with Wilcoxon rank-sum
 # Short range contacts: <= 2000000
 0_small_test_matrix.h5	1_small_test_matrix.h5	1.0
Binary file test-data/hicPlotSVL/plot.png has changed
--- a/test-data/hicPlotSVL/ratios.txt	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicPlotSVL/ratios.txt	Mon Jul 01 20:12:19 2024 +0000
@@ -1,4 +1,4 @@
-# Created with HiCExplorer's hicPlotSVL 3.7.2
+# Created with HiCExplorer's hicPlotSVL 3.7.5
 # Short range vs long range contacts per chromosome: raw data
 # Short range contacts: <= 2000000
 #	0_small_test_matrix.h5			1_small_test_matrix.h5
--- a/test-data/hicQuickQC/QC.log	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicQuickQC/QC.log	Mon Jul 01 20:12:19 2024 +0000
@@ -1,5 +1,5 @@
 
-File	/var/folders/nm/9sgmbhhj6gn_h8b308xvhm0w0000gt/T/tmp8sucpx99.h5		
+File	/tmp/tmpjkr0wi60/tmp/tmp8o_td4fd.h5		
 Sequenced reads	983		
 Min rest. site distance	300		
 Max library insert size	1000		
Binary file test-data/hicTADClassifier/unittest_classifier.BIN has changed
--- a/test-data/hicTrainTADClassifier/multiFDR_dekker_domains.bed	Wed Oct 18 10:44:35 2023 +0000
+++ /dev/null	Thu Jan 01 00:00:00 1970 +0000
@@ -1,26 +0,0 @@
-chr2L	800001	1550001	ID_0.01_1	0.022884658057	.	800001	1550001	31,120,180
-chr2L	1550001	2100001	ID_0.01_2	-0.744086372037	.	1550001	2100001	51,160,44
-chr2L	2100001	2400001	ID_0.01_3	0.311391232701	.	2100001	2400001	31,120,180
-chr2L	2400001	2750001	ID_0.01_4	0.078149036231	.	2400001	2750001	51,160,44
-chr2L	2750001	3700001	ID_0.01_5	-0.648971714281	.	2750001	3700001	31,120,180
-chr2L	3700001	4200001	ID_0.01_6	-0.133385571846	.	3700001	4200001	51,160,44
-chr2L	4200001	5050001	ID_0.01_7	-0.598347187435	.	4200001	5050001	31,120,180
-chr2L	5050001	5450001	ID_0.01_8	-0.589296128895	.	5050001	5450001	51,160,44
-chr2L	5450001	6550001	ID_0.01_9	-0.463215188679	.	5450001	6550001	31,120,180
-chr2L	6550001	7250001	ID_0.01_10	-0.739312227247	.	6550001	7250001	51,160,44
-chr2L	7250001	7650001	ID_0.01_11	-0.558267533146	.	7250001	7650001	31,120,180
-chr2L	7650001	8100001	ID_0.01_12	-0.164474310036	.	7650001	8100001	51,160,44
-chr2L	8100001	8950001	ID_0.01_13	-0.618832592666	.	8100001	8950001	31,120,180
-chr2L	8950001	10450001	ID_0.01_14	-0.547147684409	.	8950001	10450001	51,160,44
-chr2L	10450001	10800001	ID_0.01_15	-0.938748995456	.	10450001	10800001	31,120,180
-chr2L	10800001	11600001	ID_0.01_16	-0.305174734420	.	10800001	11600001	51,160,44
-chr2L	11600001	12300001	ID_0.01_17	-0.941807294590	.	11600001	12300001	31,120,180
-chr2L	12300001	12650001	ID_0.01_18	-0.124089226194	.	12300001	12650001	51,160,44
-chr2L	12650001	13150001	ID_0.01_19	-0.535969778416	.	12650001	13150001	31,120,180
-chr2L	13150001	13800001	ID_0.01_20	-0.246694822549	.	13150001	13800001	51,160,44
-chr2L	13800001	14200001	ID_0.01_21	-0.220174816848	.	13800001	14200001	31,120,180
-chr2L	14200001	15650001	ID_0.01_22	-0.512329343230	.	14200001	15650001	51,160,44
-chr2L	15650001	16250001	ID_0.01_23	-0.711741883911	.	15650001	16250001	31,120,180
-chr2L	16250001	17550001	ID_0.01_24	-0.917923384534	.	16250001	17550001	51,160,44
-chr2L	17550001	17850001	ID_0.01_25	-0.423222465610	.	17550001	17850001	31,120,180
-chr2L	17850001	18550001	ID_0.01_26	-0.274143371604	.	17850001	18550001	51,160,44
\ No newline at end of file
Binary file test-data/hicTrainTADClassifier/small_test_matrix.cool has changed
--- a/test-data/hicValidateLocations/overlap_smc3_statistics	Wed Oct 18 10:44:35 2023 +0000
+++ b/test-data/hicValidateLocations/overlap_smc3_statistics	Mon Jul 01 20:12:19 2024 +0000
@@ -1,5 +1,5 @@
-# HiCExplorer hicValidateLocations 3.7.2
-# Overlap of loop file /tmp/tmpjjk1hb59/files/a/8/9/dataset_a8916559-7d4d-42e7-b157-fdc26b57c5e2.dat with protein file /tmp/tmpjjk1hb59/files/e/5/a/dataset_e5ab267d-b489-4abc-88ce-c408eadfd25b.dat
+# HiCExplorer hicValidateLocations 3.7.5
+# Overlap of loop file /tmp/tmpjkr0wi60/files/a/f/1/dataset_af1f91e3-b1bd-4c1c-8842-935caae86bf2.dat with protein file /tmp/tmpjkr0wi60/files/e/6/e/dataset_e6e4503d-c6a1-4370-bc34-70b2fae3fc95.dat
 #
 Protein peaks: 3097
 Matched Loops: 530
Binary file test-data/li_viewpoint_32-33Mb.png has changed
Binary file test-data/li_viewpoint_32Mb.png has changed
Binary file test-data/small_test_matrix_result_sorted.bam has changed