# HG changeset patch
# User bgruening
# Date 1520412090 18000
# Node ID bb82a2982d3dd4dfe7b2d553f8f86a1d2abc65c2
# Parent  eec0210589b35b99bc5ecfc9f733e0d5ee88e3f2
planemo upload for repository https://github.com/maxplanck-ie/HiCExplorer/tree/master/galaxy/wrapper/ commit 0456f085bac2c88b8cbddfcf12b02776d2a0d457
diff -r eec0210589b3 -r bb82a2982d3d involucro
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diff -r eec0210589b3 -r bb82a2982d3d macros.xml
--- a/macros.xml	Tue Jan 02 10:12:46 2018 -0500
+++ b/macros.xml	Wed Mar 07 03:41:30 2018 -0500
@@ -1,6 +1,13 @@
 
     \${GALAXY_SLOTS:-4}
-    2.0
+    2.1
+
+    
+        #if $use_range.select_use_range == "yes_use_range":
+            --range $range_min:$range_max
+        #end if
+    
+
     
         
             hicexplorer
@@ -19,6 +26,23 @@
     
          
     
+    
+         
+            
+                
+                
+            
+            
+            
+                
+            
+        
+    
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+    
+        
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+    
 
     
         
@@ -300,13 +324,12 @@
         
     
     
-    
-       
+        
     
     
-        
+        
     
     
 
@@ -556,9 +579,9 @@
 
     
         
+              label="Include spacer at the end of the track." help="Width of the spacer." />
     
     
-                    
+        
     
 
diff -r eec0210589b3 -r bb82a2982d3d macros.xml.orig
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/macros.xml.orig	Wed Mar 07 03:41:30 2018 -0500
@@ -0,0 +1,585 @@
+
+    \${GALAXY_SLOTS:-4}
+<<<<<<< HEAD
+    2.0
+
+    
+        #if $use_range.select_use_range == "yes_use_range":
+            --range $range_min:$range_max
+        #end if
+    
+
+=======
+    2.1alpha1
+>>>>>>> joachimwolff-master
+    
+        
+            hicexplorer
+            
+        
+        @BINARY@ --version
+    
+
+    
+        
+            10.5281/zenodo.1133705
+            
+        
+    
+
+    
+         
+    
+    
+         
+            
+                
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+            
+            
+            
+            
+        
+    
+
+
+    
+        
+            
+            
+        
+    
+
+    
+        #set $matrices = []
+        #set $mlabels = []
+        #for $counter, $i in enumerate($input_files):
+            ln -s $i.matrix #echo str($counter)+'_matrix'#;
+            #silent $matrices.append( '%s_matrix' % $counter )
+
+            #if str($i.mlabel.value) != "":
+                #set $mlabels += ['"%s"' % ($i.mlabel.value)]
+            #else
+                #set $mlabels += ['"%s"' % ($i.matrix.name)]
+            #end if
+        #end for
+        #set $mlabels = ' '.join($mlabels)
+        #set $matrices = ' '.join($matrices)
+    
+
+
+    
+        
+    
+
+
+
+    
+        
+            
+                
+                
+            
+            
+                
+                    
+                        
+                        
+                    
+                    
+                        
+                    
+                    
+                
+            
+            
+        
+    
+
+    
+        #if $advancedOpt.used_multiple_regions.used_multiple_regions_options == 'no':
+            #if $advancedOpt.used_multiple_regions.clustering.clustering_options == 'kmeans':
+                #if int($advancedOpt.used_multiple_regions.clustering.k_kmeans) > 0:
+                    --kmeans $advancedOpt.used_multiple_regions.clustering.k_kmeans
+                #end if
+            #end if
+        #end if
+    
+
+    
+        
+    
+    
+        
+    
+    
+        
+    
+
+    
+        
+    
+
+    
+        
+    
+
+    
+        
+    
+
+    
+        
+    
+
+    
+        
+        
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+
+    
+        
+    
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+    
+        
+
+        
+    
+
+    
+        
+    
+    
+        
+    
+    
+        
+    
+    
+
+.. class:: infomark
+
+For more information on the tools, please visit our `help site`_.
+
+If you would like to give us feedback or you run into any trouble, please send an email to deeptools@googlegroups.com
+
+This tool is developed by the `Bioinformatics and Deep-Sequencing Unit`_ at the `Max Planck Institute for Immunobiology and Epigenetics`_.
+
+.. _Bioinformatics and Deep-Sequencing Unit: http://www3.ie-freiburg.mpg.de/facilities/research-facilities/bioinformatics-and-deep-sequencing-unit/
+.. _Max Planck Institute for Immunobiology and Epigenetics: http://www3.ie-freiburg.mpg.de
+.. _help site: https://hicexplorer.readthedocs.org
+
+    
+
+
+    
+        
+            
+            
+        
+    
+
+    
+        
+            
+            
+        
+    
+
+    
+        
+    
+
+    
+        #import tempfile
+        #set $temp_dir = os.path.abspath(tempfile.mkdtemp())
+        #set files=[]
+        #set labels=[]
+        #for $i in $input_files:
+            #set $temp_input_handle = tempfile.NamedTemporaryFile( dir=$temp_dir )
+            #set $temp_input_path = $temp_input_handle.name
+            #silent $temp_input_handle.close()
+            #silent os.system("ln -s %s %s.bam" % (str($i.bamfile), $temp_input_path))
+            #silent os.system("ln -s %s %s.bam.bai" % (str($i.bamfile.metadata.bam_index), $temp_input_path))
+            #silent $files.append('%s.bam' % $temp_input_path)
+
+            ##set $files += [str($i.bamfile)]
+            #if str($i.label.value) != "":
+                #set $labels += ["\"%s\"" % ($i.label.value)]
+            #else
+                #set $labels += ["\"%s\"" % ($i.bamfile.name)]
+            #end if
+        #end for
+    
+
+    
+        #import tempfile
+        #set $temp_dir = os.path.abspath(tempfile.mkdtemp())
+        #set files=[]
+        #set labels=[]
+        #for $i in $input_files:
+            #set $temp_input_handle = tempfile.NamedTemporaryFile( dir=$temp_dir )
+            #set $temp_input_path = $temp_input_handle.name
+            #silent $temp_input_handle.close()
+            #silent os.system("ln -s %s %s.bw" % (str($i.bigwigfile), $temp_input_path))
+            #silent $files.append('%s.bw' % $temp_input_path)
+
+            ##set $files += [str($i.bigwigfile)]
+            #if str($i.label.value) != "":
+                #set $labels += ["\"%s\"" % ($i.label.value)]
+            #else
+                #set $labels += ["\"%s\"" % ($i.bigwigfile.name)]
+            #end if
+        #end for
+    
+
+    
+        
+            
+                
+                
+            
+            
+                
+                    
+                        
+                        
+                    
+                
+            
+            
+                
+            
+        
+    
+
+    
+    #if $source.ref_source=="history":
+        --genome $source.input1
+    #else:
+        --genome "${source.input1_2bit.fields.path}"
+    #end if
+    
+
+    
+        
+            
+                
+                
+                
+                
+                
+            
+            
+                
+            
+            
+            
+            
+            
+        
+    
+
+    
+        
+            
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+        
+    
+
+    
+                
+    
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+    
+        
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+    
+        
+            
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+            
+        
+    
+
+    
+        
+            
+            
+            
+            
+            
+        
+    
+
+    
+        
+            
+                
+                
+                
+                
+            
+        
+    
+
+    
+        
+            
+            ((
+                output['showOutputSettings'] == 'yes' and
+                output['saveMatrix'] is True
+            ))
+            
+        
+    
+
+    
+        
+            
+            ((
+                output['showOutputSettings'] == 'yes' and
+                output['saveData'] is True
+            ))
+            
+        
+        
+            
+            ((
+                output['showOutputSettings'] == 'yes' and
+                output['saveSortedRegions'] is True
+            ))
+            
+        
+    
+
+    
+        
+    
+    
+        
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+
diff -r eec0210589b3 -r bb82a2982d3d test-data/Li_chrX30-35_cool.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/compare_matrices_log2ratio.h5
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diff -r eec0210589b3 -r bb82a2982d3d test-data/compare_matrices_pearson_ratio.cool
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diff -r eec0210589b3 -r bb82a2982d3d test-data/covariance_small_50kb.cool
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diff -r eec0210589b3 -r bb82a2982d3d test-data/covariance_small_50kb.h5
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diff -r eec0210589b3 -r bb82a2982d3d test-data/diagnostic_plot.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicAggregateContacts_results1.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicCorrectMatrix_result1.npz.h5
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicCorrelate_heatmap_result1.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicCorrelate_scatter_result1.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicMergeMatrixBins_result1.npz.h5
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicPlotDistVsCounts_result1.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicPlotDistVsCounts_result2.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/hicSumMatrices_result1.npz.h5
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diff -r eec0210589b3 -r bb82a2982d3d test-data/li_viewpoint_32-33Mb.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/li_viewpoint_32Mb.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/master_TADs_plot.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/master_matrix_plot.png
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diff -r eec0210589b3 -r bb82a2982d3d test-data/multiFDR_boundaries.bed
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/multiFDR_boundaries.bed	Wed Mar 07 03:41:30 2018 -0500
@@ -0,0 +1,2 @@
+chr2L	22922500	22927500	B04585	-0.068256362891	.
+chrX	87500	92500	B19358	-0.072020401017	.
diff -r eec0210589b3 -r bb82a2982d3d test-data/multiFDR_boundaries.gff
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/multiFDR_boundaries.gff	Wed Mar 07 03:41:30 2018 -0500
@@ -0,0 +1,2 @@
+chr2L	HiCExplorer	boundary	22922500	22927500	-0.068256362891	.	.	ID=B04585;delta=0.021954846720;pvalue=0.000033964776;tad_sep=-0.068256362891
+chrX	HiCExplorer	boundary	87500	92500	-0.072020401017	.	.	ID=B19358;delta=0.019799980104;pvalue=0.000055223433;tad_sep=-0.072020401017
diff -r eec0210589b3 -r bb82a2982d3d test-data/multiFDR_domains.bed
diff -r eec0210589b3 -r bb82a2982d3d test-data/multiFDR_score.bedgraph
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/multiFDR_score.bedgraph	Wed Mar 07 03:41:30 2018 -0500
@@ -0,0 +1,23814 @@
+chr2L	2500	7500	-0.164488846397
+chr2L	7500	12500	0.004155516280
+chr2L	12500	17500	0.260509497302
+chr2L	17500	22500	0.126728724578
+chr2L	22500	27500	0.107536542495
+chr2L	27500	32500	0.067996441287
+chr2L	32500	37500	0.180067325085
+chr2L	37500	42500	0.188704045555
+chr2L	42500	47500	0.123071283383
+chr2L	47500	52500	0.090946822420
+chr2L	52500	57500	0.050290136708
+chr2L	57500	62500	0.043738171585
+chr2L	62500	67500	0.036458137676
+chr2L	67500	72500	-0.008311665224
+chr2L	72500	77500	-0.025506335364
+chr2L	77500	82500	-0.028782499450
+chr2L	82500	87500	-0.008859983289
+chr2L	87500	92500	0.012581289189
+chr2L	92500	97500	-0.026656341295
+chr2L	97500	102500	-0.064470557052
+chr2L	102500	107500	-0.022699733707
+chr2L	107500	112500	-0.026264267296
+chr2L	112500	117500	-0.009926677809
+chr2L	117500	122500	-0.006876513913
+chr2L	122500	127500	0.016147318959
+chr2L	127500	132500	0.022378914981
+chr2L	132500	137500	0.070952047599
+chr2L	137500	142500	0.071053469305
+chr2L	142500	147500	0.068034199638
+chr2L	147500	152500	0.067090397637
+chr2L	152500	157500	0.057311311696
+chr2L	157500	162500	0.067610279560
+chr2L	162500	167500	0.029002777185
+chr2L	167500	172500	0.029002777185
+chr2L	172500	177500	0.008980247068
+chr2L	177500	182500	0.016907224460
+chr2L	182500	187500	-0.000150569937
+chr2L	187500	192500	0.010495785312
+chr2L	192500	197500	-0.048163268016
+chr2L	197500	202500	-0.039867994837
+chr2L	202500	207500	-0.046910414090
+chr2L	207500	212500	-0.055696730183
+chr2L	212500	217500	-0.036501614110
+chr2L	217500	222500	-0.036501614110
+chr2L	222500	227500	-0.023335648652
+chr2L	227500	232500	-0.023335648652
+chr2L	232500	237500	-0.038011760274
+chr2L	237500	242500	-0.040574053585
+chr2L	242500	247500	-0.052320501930
+chr2L	247500	252500	-0.065486467388
+chr2L	252500	257500	-0.053000848584
+chr2L	257500	262500	-0.053000848584
+chr2L	262500	267500	-0.022469370040
+chr2L	267500	272500	-0.038170498789
+chr2L	272500	277500	-0.059012201761
+chr2L	277500	282500	-0.086006441495
+chr2L	282500	287500	-0.053031533287
+chr2L	287500	292500	-0.053031533287
+chr2L	292500	297500	-0.083051915395
+chr2L	297500	302500	-0.083051915395
+chr2L	302500	307500	-0.051758175573
+chr2L	307500	312500	-0.044639541179
+chr2L	312500	317500	-0.043712800180
+chr2L	317500	322500	-0.019156222003
+chr2L	322500	327500	-0.017442079268
+chr2L	327500	332500	0.041070352715
+chr2L	332500	337500	0.049256940562
+chr2L	337500	342500	0.053147123147
+chr2L	342500	347500	0.053147123147
+chr2L	347500	352500	0.078905602777
+chr2L	352500	357500	0.093459536727
+chr2L	357500	362500	0.079684892703
+chr2L	362500	367500	0.063143859889
+chr2L	367500	372500	0.092016050812
+chr2L	372500	377500	0.061075544744
+chr2L	377500	382500	0.013498603323
+chr2L	382500	387500	0.029781933737
+chr2L	387500	392500	-0.021388944213
+chr2L	392500	397500	-0.038792978876
+chr2L	397500	402500	-0.050263472402
+chr2L	402500	407500	-0.044321193230
+chr2L	407500	412500	-0.007732343879
+chr2L	412500	417500	-0.013295314500
+chr2L	417500	422500	-0.013295314500
+chr2L	422500	427500	-0.021132388853
+chr2L	427500	432500	-0.021015012893
+chr2L	432500	437500	-0.015982567418
+chr2L	437500	442500	-0.049145302596
+chr2L	442500	447500	-0.064964420946
+chr2L	447500	452500	-0.051664858126
+chr2L	452500	457500	-0.071914886809
+chr2L	457500	462500	-0.069724393991
+chr2L	462500	467500	-0.069724393991
+chr2L	467500	472500	-0.059605045512
+chr2L	472500	477500	-0.051309772332
+chr2L	477500	482500	-0.048373705573
+chr2L	482500	487500	-0.048373705573
+chr2L	487500	492500	-0.014227247533
+chr2L	492500	497500	-0.064541001831
+chr2L	497500	502500	-0.064541001831
+chr2L	502500	507500	-0.056245728652
+chr2L	507500	512500	-0.064541001831
+chr2L	512500	517500	-0.071946857401
+chr2L	517500	522500	-0.071946857401
+chr2L	522500	527500	-0.071946857401
+chr2L	527500	532500	-0.076979302876
+chr2L	532500	537500	-0.076979302876
+chr2L	537500	542500	-0.076979302876
+chr2L	542500	547500	-0.120135452320
+chr2L	547500	552500	-0.107649833515
+chr2L	552500	557500	-0.087399804832
+chr2L	557500	562500	-0.099885423637
+chr2L	562500	567500	-0.099885423637
+chr2L	567500	572500	-0.099885423637
+chr2L	572500	577500	-0.099885423637
+chr2L	577500	582500	-0.099885423637
+chr2L	582500	587500	-0.084057834311
+chr2L	587500	592500	-0.084057834311
+chr2L	592500	597500	-0.065926294209
+chr2L	597500	602500	-0.076626770847
+chr2L	602500	607500	-0.063204938090
+chr2L	607500	612500	-0.066951827756
+chr2L	612500	617500	-0.066951827756
+chr2L	617500	622500	-0.095049772135
+chr2L	622500	627500	-0.086559234121
+chr2L	627500	632500	-0.104690774223
+chr2L	632500	637500	-0.104690774223
+chr2L	637500	642500	-0.104690774223
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+chr2R	18987500	18992500	0.083081172044
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+chr2R	19022500	19027500	0.059052989451
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+chr2R	19032500	19037500	0.089830010203
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+chr3L	19392500	19397500	0.105272224143
+chr3L	19397500	19402500	0.115324280976
+chr3L	19402500	19407500	0.119360096699
+chr3L	19407500	19412500	0.068930074919
+chr3L	19412500	19417500	0.011787914307
+chr3L	19417500	19422500	0.041788492265
+chr3L	19422500	19427500	0.032614862047
+chr3L	19427500	19432500	0.025319493449
+chr3L	19432500	19437500	0.045172756923
+chr3L	19437500	19442500	0.044335198739
+chr3L	19442500	19447500	0.060192087364
+chr3L	19447500	19452500	0.070175529297
+chr3L	19452500	19457500	0.067381829151
+chr3L	19457500	19462500	0.047556702269
+chr3L	19462500	19467500	0.042421575615
+chr3L	19467500	19472500	0.019155929686
+chr3L	19472500	19477500	0.002976166589
+chr3L	19477500	19482500	-0.015996268678
+chr3L	19482500	19487500	-0.022678469161
+chr3L	19487500	19492500	-0.052371383469
+chr3L	19492500	19497500	-0.054524320941
+chr3L	19497500	19502500	-0.059527882540
+chr3L	19502500	19507500	-0.074313625067
+chr3L	19507500	19512500	-0.059570301509
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+chr3L	19522500	19527500	-0.029273491797
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+chr3L	19562500	19567500	0.000989707205
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diff -r eec0210589b3 -r bb82a2982d3d test-data/multiFDR_tad_score.bm
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/multiFDR_tad_score.bm	Wed Mar 07 03:41:30 2018 -0500
@@ -0,0 +1,23830 @@
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+chr2L	19820000	19825000	-0.082811	0.051552	0.061903	0.023588
+chr2L	19825000	19830000	-0.049630	0.070217	0.070198	0.036806
+chr2L	19830000	19835000	-0.113302	-0.043200	0.037739	0.019637
+chr2L	19835000	19840000	-0.113302	-0.043200	0.054434	0.019637
+chr2L	19840000	19845000	-0.021819	-0.061056	0.027624	0.024025
+chr2L	19845000	19850000	0.073268	-0.007569	0.071440	0.030409
+chr2L	19850000	19855000	0.073268	0.053425	0.085218	0.019454
+chr2L	19855000	19860000	0.073268	0.053425	0.085218	0.019454
+chr2L	19860000	19865000	0.100770	0.037896	0.078316	0.026977
+chr2L	19865000	19870000	0.054464	0.042848	0.080517	0.028141
+chr2L	19870000	19875000	0.032426	0.033251	0.017255	0.016148
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+chr2L	19880000	19885000	0.091975	0.073311	-0.002451	-0.001507
+chr2L	19885000	19890000	0.091975	0.073311	-0.002451	-0.001507
+chr2L	19890000	19895000	0.091975	0.040516	-0.002451	0.011720
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+chr2L	19900000	19905000	0.099082	0.044514	0.000981	0.024217
+chr2L	19905000	19910000	0.045756	0.006951	0.022107	0.024217
+chr2L	19910000	19915000	-0.009353	0.006951	0.022107	0.050220
+chr2L	19915000	19920000	-0.009353	0.043471	0.022107	0.037258
+chr2L	19920000	19925000	0.018254	0.028001	0.015232	0.009384
+chr2L	19925000	19930000	-0.036855	-0.001995	-0.005894	0.009384
+chr2L	19930000	19935000	-0.036855	0.026980	0.010038	0.028060
+chr2L	19935000	19940000	-0.061792	-0.010500	-0.008275	0.030339
+chr2L	19940000	19945000	-0.061792	-0.010500	-0.008275	0.030339
+chr2L	19945000	19950000	-0.061792	0.022295	-0.004775	0.052276
+chr2L	19950000	19955000	-0.061792	0.022295	-0.004775	0.052276
+chr2L	19955000	19960000	-0.020141	0.039808	0.041485	0.056148
+chr2L	19960000	19965000	-0.053323	0.021144	0.033190	0.051760
+chr2L	19965000	19970000	0.004979	0.058013	0.052567	0.037523
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+chr2L	19975000	19980000	0.118168	0.054557	0.085672	0.034122
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+chr2L	20015000	20020000	0.090044	0.073894	0.097421	0.028137
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+chr3L	19745000	19750000	0.029024	0.042998	-0.028745	0.019188
+chr3L	19750000	19755000	0.029024	0.042998	-0.028745	0.019188
+chr3L	19755000	19760000	-0.035696	-0.030152	-0.028745	0.019188
+chr3L	19760000	19765000	-0.144931	-0.030152	-0.028745	0.006094
+chr3L	19765000	19770000	-0.144931	-0.030152	-0.028745	-0.007298
+chr3L	19770000	19775000	-0.144931	-0.030152	-0.028745	-0.022003
+chr3L	19775000	19780000	-0.144931	-0.094680	-0.057424	-0.037172
+chr3L	19780000	19785000	-0.144931	-0.128002	-0.057424	-0.037172
+chr3L	19785000	19790000	-0.144931	-0.128002	-0.073177	-0.057873
+chr3L	19790000	19795000	-0.144931	-0.128002	-0.087987	-0.078801
+chr3L	19795000	19800000	-0.144931	-0.128002	-0.104745	-0.087665
+chr3L	19800000	19805000	-0.144931	-0.128002	-0.089936	-0.079832
+chr3L	19805000	19810000	-0.090864	-0.097589	-0.076419	-0.072682
+chr3L	19810000	19815000	-0.090864	-0.064267	-0.076419	-0.072682
+chr3L	19815000	19820000	-0.067764	-0.051274	-0.070644	-0.069628
+chr3L	19820000	19825000	-0.067764	-0.051274	-0.070644	-0.069628
+chr3L	19825000	19830000	-0.098516	-0.068572	-0.078332	-0.061325
+chr3L	19830000	19835000	0.019950	-0.035257	-0.063525	-0.053493
+chr3L	19835000	19840000	0.019950	-0.035257	-0.063525	-0.041549
+chr3L	19840000	19845000	-0.003366	-0.048371	-0.069354	-0.044632
+chr3L	19845000	19850000	-0.003366	-0.048371	-0.069354	-0.044632
+chr3L	19850000	19855000	-0.003366	-0.048371	-0.069354	-0.044632
+chr3L	19855000	19860000	-0.003366	-0.048371	-0.046772	-0.044632
+chr3L	19860000	19865000	-0.062605	-0.048371	-0.046772	-0.044632
+chr3L	19865000	19870000	-0.098516	-0.068572	-0.055750	-0.049381
+chr3L	19870000	19875000	-0.080875	-0.058648	-0.027954	-0.047048
+chr3L	19875000	19880000	-0.058454	-0.046037	-0.022349	-0.044083
+chr3L	19880000	19885000	-0.058454	-0.079359	-0.022349	-0.044083
+chr3L	19885000	19890000	-0.081770	-0.092474	-0.011419	-0.038302
+chr3L	19890000	19895000	-0.107516	-0.106956	-0.016773	-0.041135
+chr3L	19895000	19900000	-0.107516	-0.028024	-0.004274	-0.034523
+chr3L	19900000	19905000	-0.071605	-0.007824	0.004704	-0.029775
+chr3L	19905000	19910000	-0.109020	-0.028870	-0.004650	-0.034722
+chr3L	19910000	19915000	-0.059023	-0.028870	-0.004650	-0.034722
+chr3L	19915000	19920000	-0.018067	-0.020884	0.005589	-0.029306
+chr3L	19920000	19925000	-0.035708	-0.030807	0.019985	-0.021692
+chr3L	19925000	19930000	0.002635	0.028468	0.006185	-0.016622
+chr3L	19930000	19935000	0.043369	0.051381	0.016368	-0.011236
+chr3L	19935000	19940000	0.158175	0.109767	0.042318	0.002490
+chr3L	19940000	19945000	0.168339	0.145049	0.057999	0.010784
+chr3L	19945000	19950000	0.281628	0.179209	0.073181	0.018814
+chr3L	19950000	19955000	0.270620	0.179209	0.087121	0.026187
+chr3L	19955000	19960000	0.240695	0.232814	0.069557	0.028841
+chr3L	19960000	19965000	0.210459	0.215806	0.061998	0.035708
+chr3L	19965000	19970000	0.259727	0.237177	0.090068	0.050554
+chr3L	19970000	19975000	0.216346	0.178460	0.079863	0.032788
+chr3L	19975000	19980000	0.200827	0.156980	0.070317	0.015794
+chr3L	19980000	19985000	0.178161	0.156980	0.070317	0.015794
+chr3L	19985000	19990000	0.263164	0.143866	0.079298	0.020544
+chr3L	19990000	19995000	0.280805	0.153789	0.083708	0.022877
+chr3L	19995000	20000000	0.189936	0.201005	0.058239	0.009406
+chr3L	20000000	20005000	0.137377	0.158691	0.058239	0.009406
+chr3L	20005000	20010000	0.190300	0.188460	0.075251	0.007540
+chr3L	20010000	20015000	0.107365	0.143609	0.069257	0.004369
+chr3L	20015000	20020000	0.282174	0.143609	0.069257	0.004369
+chr3L	20020000	20025000	0.232905	0.115896	0.056940	-0.002146
+chr3L	20025000	20030000	0.118400	0.118295	0.044067	-0.008955
+chr3L	20030000	20035000	0.045173	0.075304	0.038900	-0.011688
+chr3L	20035000	20040000	-0.007386	0.104869	0.033233	-0.014685
+chr3L	20040000	20045000	-0.007386	0.101641	0.011258	-0.015444
+chr3L	20045000	20050000	0.062767	0.022150	-0.022258	-0.033171
+chr3L	20050000	20055000	0.062767	0.022150	-0.022258	-0.033171
+chr3L	20055000	20060000	0.062767	0.022150	-0.022258	-0.033171
+chr3L	20060000	20065000	0.103501	0.045063	-0.012075	-0.027785
+chr3L	20065000	20070000	0.126356	0.054161	0.006779	-0.017813
+chr3L	20070000	20075000	0.105277	0.073669	0.015449	-0.003511
+chr3L	20075000	20080000	0.105277	0.080509	0.020672	-0.000748
+chr3L	20080000	20085000	0.165703	0.114499	0.035779	0.023276
+chr3L	20085000	20090000	0.165703	0.114499	0.054149	0.012412
+chr3L	20090000	20095000	0.156770	0.145879	0.068096	0.034483
+chr3L	20095000	20100000	0.108504	0.111888	0.052989	0.035439
+chr3L	20100000	20105000	0.020949	0.088976	0.042806	0.030052
+chr3L	20105000	20110000	-0.080212	0.002508	0.007350	0.003684
+chr3L	20110000	20115000	0.087087	0.044822	0.007350	0.017076
+chr3L	20115000	20120000	0.087087	0.044822	0.007350	0.017076
+chr3L	20120000	20125000	0.087087	0.044822	0.007350	0.017076
+chr3L	20125000	20130000	0.087087	0.086156	0.037664	0.030469
+chr3L	20130000	20135000	0.162312	0.086156	0.007350	0.045170
+chr3L	20135000	20140000	-0.033391	0.086156	0.007350	0.045170
+chr3L	20140000	20145000	-0.033391	0.086156	0.007350	0.045170
+chr3L	20145000	20150000	0.127212	0.214551	0.047501	0.066407
+chr3L	20150000	20155000	0.044852	0.163295	0.043090	0.064074
+chr3L	20155000	20160000	0.021537	0.040097	0.046402	0.052434
+chr3L	20160000	20165000	0.021537	0.040097	0.046402	0.052434
+chr3L	20165000	20170000	-0.038395	0.032722	0.043124	0.050700
+chr3L	20170000	20175000	-0.056036	-0.039942	0.022209	0.011543
+chr3L	20175000	20180000	-0.018621	-0.056953	0.031563	-0.015568
+chr3L	20180000	20185000	-0.018621	-0.056953	0.031563	-0.015568
+chr3L	20185000	20190000	-0.036040	-0.066751	0.027208	-0.017872
+chr3L	20190000	20195000	-0.084201	-0.093841	-0.022009	-0.034187
+chr3L	20195000	20200000	-0.107516	-0.106956	-0.053158	-0.037270
+chr3L	20200000	20205000	-0.107516	-0.106956	-0.053158	-0.037270
+chr3L	20205000	20210000	-0.060983	-0.080781	-0.041524	-0.040834
+chr3L	20210000	20215000	-0.060983	-0.080781	-0.066844	-0.040834
+chr3L	20215000	20220000	-0.060983	-0.080781	-0.083758	-0.040834
+chr3L	20220000	20225000	-0.060983	-0.080781	-0.083758	-0.040834
+chr3L	20225000	20230000	-0.043342	-0.070858	-0.079348	-0.047447
+chr3L	20230000	20235000	-0.052525	-0.046459	-0.068504	-0.041711
+chr3L	20235000	20240000	-0.052525	-0.046459	-0.068504	-0.041711
+chr3L	20240000	20245000	0.000034	-0.046459	-0.068504	-0.055104
+chr3L	20245000	20250000	0.046449	-0.020350	-0.056900	-0.039250
+chr3L	20250000	20255000	0.046449	-0.020350	-0.056900	-0.039250
+chr3L	20255000	20260000	0.046449	-0.020350	-0.056900	-0.052642
+chr3L	20260000	20265000	0.034595	-0.027018	-0.041493	-0.054210
+chr3L	20265000	20270000	0.034595	-0.027018	-0.041493	-0.054210
+chr3L	20270000	20275000	0.069877	-0.007172	-0.032673	-0.049544
+chr3L	20275000	20280000	0.052236	-0.017095	-0.037083	-0.051877
+chr3L	20280000	20285000	0.027369	-0.031083	-0.043300	-0.045671
+chr3L	20285000	20290000	0.027369	-0.031083	-0.043300	-0.045671
+chr3L	20290000	20295000	-0.062605	-0.052129	-0.052654	-0.050618
+chr3L	20295000	20300000	0.049828	0.011115	-0.024545	-0.035751
+chr3L	20300000	20305000	0.032187	0.012960	-0.042095	-0.045033
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+chr3L	20310000	20315000	-0.060859	-0.039378	-0.047406	-0.057337
+chr3L	20315000	20320000	-0.061488	-0.039732	-0.030805	-0.048556
+chr3L	20320000	20325000	-0.096770	-0.059578	-0.039625	-0.053222
+chr3L	20325000	20330000	-0.096770	-0.100911	-0.039625	-0.053222
+chr3L	20330000	20335000	-0.096770	-0.100911	-0.039625	-0.053222
+chr3L	20335000	20340000	-0.096770	-0.100911	-0.039625	-0.053222
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+chr3L	20350000	20355000	-0.144931	-0.087613	-0.051666	-0.059590
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+chr3L	20360000	20365000	-0.078478	-0.052915	-0.035053	-0.035273
+chr3L	20365000	20370000	-0.055163	-0.039800	-0.047594	-0.032190
+chr3L	20370000	20375000	-0.052731	-0.038433	-0.046986	-0.031868
+chr3L	20375000	20380000	-0.076047	-0.023424	-0.040316	-0.028340
+chr3L	20380000	20385000	-0.006316	0.015799	-0.022883	-0.028836
+chr3L	20385000	20390000	-0.032063	0.001317	-0.029320	-0.032241
+chr3L	20390000	20395000	-0.005382	-0.011798	-0.035149	-0.050854
+chr3L	20395000	20400000	-0.005382	-0.049505	-0.035149	-0.050854
+chr3L	20400000	20405000	0.037756	-0.025240	-0.042315	-0.045150
+chr3L	20405000	20410000	0.075714	-0.003889	-0.032825	-0.040130
+chr3L	20410000	20415000	0.075714	-0.003889	-0.032825	-0.040130
+chr3L	20415000	20420000	0.111625	0.016311	-0.023848	-0.035382
+chr3L	20420000	20425000	0.111625	0.016311	-0.023848	-0.035382
+chr3L	20425000	20430000	0.111625	0.016311	-0.023848	-0.035382
+chr3L	20430000	20435000	0.120082	0.021068	-0.021733	-0.043758
+chr3L	20435000	20440000	0.070086	0.021068	-0.038492	-0.052622
+chr3L	20440000	20445000	0.124368	0.051602	-0.024921	-0.045444
+chr3L	20445000	20450000	0.165102	0.074515	-0.014738	-0.040058
+chr3L	20450000	20455000	0.041854	-0.022935	-0.058049	-0.062966
+chr3L	20455000	20460000	0.041854	-0.022935	-0.058049	-0.062966
+chr3L	20460000	20465000	0.011102	-0.040233	-0.065737	-0.067033
+chr3L	20465000	20470000	-0.061060	-0.080824	-0.083777	-0.076575
+chr3L	20470000	20475000	-0.026380	-0.061317	-0.075107	-0.071989
+chr3L	20475000	20480000	-0.026380	-0.061317	-0.075107	-0.071989
+chr3L	20480000	20485000	-0.069517	-0.085582	-0.085892	-0.077693
+chr3L	20485000	20490000	-0.110251	-0.108495	-0.096075	-0.083079
+chr3L	20490000	20495000	-0.110251	-0.108495	-0.096075	-0.083079
+chr3L	20495000	20500000	-0.127290	-0.118079	-0.100335	-0.085332
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+chr3L	20505000	20510000	-0.144931	-0.128002	-0.104745	-0.076801
+chr3L	20510000	20515000	-0.144931	-0.128002	-0.104745	-0.076801
+chr3L	20515000	20520000	-0.144931	-0.128002	-0.104745	-0.076801
+chr3L	20520000	20525000	-0.144931	-0.128002	-0.104745	-0.076801
+chr3L	20525000	20530000	-0.144931	-0.128002	-0.104745	-0.076801
+chr3L	20530000	20535000	-0.144931	-0.128002	-0.104745	-0.066217
+chr3L	20535000	20540000	-0.144931	-0.128002	-0.104745	-0.066217
+chr3L	20540000	20545000	-0.144931	-0.128002	-0.104745	-0.066217
+chr3L	20545000	20550000	-0.144931	-0.128002	-0.084205	-0.055018
+chr3L	20550000	20555000	-0.144931	-0.128002	-0.084205	-0.055018
+chr3L	20555000	20560000	-0.144931	-0.128002	-0.084205	-0.036525
+chr3L	20560000	20565000	-0.085705	-0.094687	-0.069398	-0.028693
+chr3L	20565000	20570000	-0.085705	-0.094687	-0.049388	-0.028693
+chr3L	20570000	20575000	-0.109020	-0.107802	-0.055217	-0.031776
+chr3L	20575000	20580000	-0.109020	-0.107802	-0.055217	-0.031776
+chr3L	20580000	20585000	-0.109020	-0.107802	-0.060005	-0.023444
+chr3L	20585000	20590000	-0.011787	-0.053109	-0.035696	-0.010587
+chr3L	20590000	20595000	0.081043	-0.000891	0.008684	0.001688
+chr3L	20595000	20600000	0.045132	-0.021091	-0.000293	0.009309
+chr3L	20600000	20605000	0.019385	-0.035574	0.007675	0.023019
+chr3L	20605000	20610000	0.031771	0.048828	0.010772	0.024656
+chr3L	20610000	20615000	0.031771	0.039249	0.010772	0.037028
+chr3L	20615000	20620000	0.031771	0.039249	0.010772	0.018535
+chr3L	20620000	20625000	0.031771	0.039249	0.010772	0.018535
+chr3L	20625000	20630000	0.141489	0.068553	0.023796	0.014559
+chr3L	20630000	20635000	0.204500	0.068553	0.041746	0.014559
+chr3L	20635000	20640000	0.204500	0.068553	0.041746	0.014559
+chr3L	20640000	20645000	0.141489	0.068553	0.065132	0.014559
+chr3L	20645000	20650000	0.141489	0.068553	0.065132	0.014559
+chr3L	20650000	20655000	0.066299	0.026259	0.026325	0.004617
+chr3L	20655000	20660000	0.005521	-0.007929	0.034521	-0.003420
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+chr3L	20665000	20670000	-0.052101	-0.043373	0.013348	-0.003420
+chr3L	20670000	20675000	-0.052101	-0.002984	0.013348	-0.003420
+chr3L	20675000	20680000	-0.052101	-0.002984	0.013348	-0.003420
+chr3L	20680000	20685000	-0.052101	-0.075785	0.013348	-0.003420
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+chr3L	20690000	20695000	-0.104197	-0.105089	-0.029834	-0.036844
+chr3L	20695000	20700000	-0.104197	-0.105089	-0.053220	-0.036844
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+chr3L	20710000	20715000	0.016059	-0.037445	-0.023157	-0.032141
+chr3L	20715000	20720000	0.016059	-0.037445	-0.023157	-0.032141
+chr3L	20720000	20725000	0.039374	-0.024330	-0.058669	-0.029058
+chr3L	20725000	20730000	-0.012724	-0.053636	-0.071694	-0.035947
+chr3L	20730000	20735000	0.043259	-0.022145	-0.057698	-0.028544
+chr3L	20735000	20740000	0.095376	0.007171	-0.030729	-0.005334
+chr3L	20740000	20745000	0.095376	0.007171	-0.030729	-0.017703
+chr3L	20745000	20750000	0.069629	-0.007312	-0.020252	-0.002614
+chr3L	20750000	20755000	0.021468	-0.003038	-0.032292	-0.018477
+chr3L	20755000	20760000	0.021468	-0.003038	-0.032292	-0.018477
+chr3L	20760000	20765000	0.021468	0.023299	-0.020587	-0.012286
+chr3L	20765000	20770000	0.050019	0.013022	-0.025154	-0.012373
+chr3L	20770000	20775000	0.052225	-0.017101	-0.038542	0.003500
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+chr3R	19800000	19805000	-0.103607	-0.103564	-0.071453	-0.055957
+chr3R	19805000	19810000	-0.065882	-0.082344	-0.084257	-0.050969
+chr3R	19810000	19815000	-0.103607	-0.103564	-0.093689	-0.055957
+chr3R	19815000	19820000	-0.103607	-0.103564	-0.093689	-0.055957
+chr3R	19820000	19825000	-0.097648	-0.100212	-0.092199	-0.055169
+chr3R	19825000	19830000	-0.116511	-0.110823	-0.050783	-0.048213
+chr3R	19830000	19835000	-0.142298	-0.125328	-0.057230	-0.051623
+chr3R	19835000	19840000	-0.142298	-0.125328	-0.057230	-0.051623
+chr3R	19840000	19845000	-0.081970	-0.091393	-0.042148	-0.043646
+chr3R	19845000	19850000	-0.081970	-0.091393	-0.042148	-0.043646
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+chr3R	19855000	19860000	-0.107757	-0.065697	-0.048594	-0.058816
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+chr3R	19865000	19870000	-0.142298	-0.085127	-0.057230	-0.063384
+chr3R	19870000	19875000	-0.142298	-0.085127	-0.057230	-0.063384
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+chr3R	19880000	19885000	-0.070829	-0.085127	-0.085494	-0.051785
+chr3R	19885000	19890000	-0.142298	-0.085127	-0.085494	-0.051785
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+chr3R	19940000	19945000	-0.142298	-0.125328	-0.081432	-0.076185
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diff -r eec0210589b3 -r bb82a2982d3d test-data/multiFDR_zscore_matrix.h5
Binary file test-data/multiFDR_zscore_matrix.h5 has changed
diff -r eec0210589b3 -r bb82a2982d3d test-data/obs_exp_small_50kb.cool
Binary file test-data/obs_exp_small_50kb.cool has changed
diff -r eec0210589b3 -r bb82a2982d3d test-data/obs_exp_small_50kb.h5
Binary file test-data/obs_exp_small_50kb.h5 has changed
diff -r eec0210589b3 -r bb82a2982d3d test-data/pca1.bedgraph
--- a/test-data/pca1.bedgraph	Tue Jan 02 10:12:46 2018 -0500
+++ b/test-data/pca1.bedgraph	Wed Mar 07 03:41:30 2018 -0500
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 chrU	5950000	6000000	0.000000000000
 chrU	6000000	6050000	0.000000000000
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 chrUextra	0	50000	0.000000000000
-chrUextra	50000	100000	-0.288675134595
+chrUextra	50000	100000	-0.500000000000
 chrUextra	100000	150000	0.000000000000
-chrUextra	150000	200000	-0.288675134595
+chrUextra	150000	200000	-0.500000000000
 chrUextra	200000	250000	0.000000000000
 chrUextra	250000	300000	0.000000000000
-chrUextra	300000	350000	0.866025403784
-chrUextra	350000	400000	-0.288675134595
+chrUextra	300000	350000	-0.500000000000
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 chrUextra	400000	450000	0.000000000000
 chrUextra	450000	500000	0.000000000000
 chrUextra	500000	550000	0.000000000000
@@ -2669,49 +2669,49 @@
 chrUextra	28150000	28200000	0.000000000000
 chrUextra	28650000	28700000	0.000000000000
 chr3LHet	0	50000	0.000000000000
-chr3LHet	200000	250000	0.144509113902
-chr3LHet	250000	300000	0.145646037045
-chr3LHet	300000	350000	0.118985357619
-chr3LHet	350000	400000	0.043423176974
-chr3LHet	400000	450000	0.028483551995
-chr3LHet	450000	500000	0.155229023170
-chr3LHet	500000	550000	0.167032856035
-chr3LHet	550000	600000	-0.029445295268
-chr3LHet	600000	650000	0.175757900533
-chr3LHet	650000	700000	0.044986523886
-chr3LHet	700000	750000	0.089036809909
-chr3LHet	750000	800000	0.189426816665
-chr3LHet	800000	850000	-0.265646838742
-chr3LHet	850000	900000	0.221831756303
-chr3LHet	900000	950000	0.178725974166
-chr3LHet	950000	1000000	0.009104035833
-chr3LHet	1000000	1050000	-0.250828406646
-chr3LHet	1050000	1100000	0.005927138353
-chr3LHet	1100000	1150000	0.015496712512
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-chr3LHet	1200000	1250000	0.174397654007
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+chr3LHet	1350000	1400000	-0.069551840640
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 chr3LHet	1450000	1500000	0.000000000000
-chr3LHet	1500000	1550000	0.111775730828
-chr3LHet	1550000	1600000	0.082008066935
-chr3LHet	1600000	1650000	-0.020338141452
-chr3LHet	1650000	1700000	-0.220317246321
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-chr3LHet	1900000	1950000	-0.009306004735
-chr3LHet	1950000	2000000	-0.045777533627
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-chr3LHet	2100000	2150000	0.096991371407
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+chr3LHet	2350000	2400000	0.045158473409
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+chr3LHet	2450000	2500000	0.046643643739
+chr3LHet	2500000	2550000	0.038522077967
diff -r eec0210589b3 -r bb82a2982d3d test-data/pca1.bw
Binary file test-data/pca1.bw has changed
diff -r eec0210589b3 -r bb82a2982d3d test-data/pca2.bedgraph
--- a/test-data/pca2.bedgraph	Tue Jan 02 10:12:46 2018 -0500
+++ b/test-data/pca2.bedgraph	Wed Mar 07 03:41:30 2018 -0500
@@ -1,60 +1,60 @@
-chr2RHet	0	50000	0.177193350469
-chr2RHet	50000	100000	0.032204538347
-chr2RHet	100000	150000	-0.282387463612
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-chr2RHet	200000	250000	0.041231230909
-chr2RHet	300000	350000	0.002926389428
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-chr2RHet	700000	750000	-0.010960418117
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-chr2RHet	800000	850000	0.091930713152
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-chr2RHet	950000	1000000	-0.114441574570
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 chr2RHet	1100000	1150000	0.000000000000
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 chr2RHet	1500000	1550000	0.000000000000
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 chr2RHet	1750000	1800000	0.000000000000
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 chr2RHet	2000000	2050000	0.000000000000
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 chr2RHet	2750000	2800000	0.000000000000
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 chr2RHet	3000000	3050000	0.000000000000
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 chr2RHet	3100000	3150000	0.000000000000
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 chr3RHet	0	50000	0.284466569482
 chr3RHet	50000	100000	0.204455883661
 chr3RHet	100000	150000	0.143212426746
@@ -1086,60 +1086,60 @@
 chr2L	22850000	22900000	0.018650800653
 chr2L	22900000	22950000	0.115559833047
 chr2L	22950000	23000000	0.020669766894
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 chrU	3100000	3150000	0.000000000000
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 chrU	3600000	3650000	0.000000000000
 chrU	3650000	3700000	0.000000000000
 chrU	3850000	3900000	0.000000000000
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 chrU	5550000	5600000	0.000000000000
 chrU	5600000	5650000	0.000000000000
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 chrU	5750000	5800000	0.000000000000
 chrU	5950000	6000000	0.000000000000
 chrU	6000000	6050000	0.000000000000
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diff -r eec0210589b3 -r bb82a2982d3d test-data/pca2.bw
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diff -r eec0210589b3 -r bb82a2982d3d test-data/pearson_small_50kb.cool
Binary file test-data/pearson_small_50kb.cool has changed
diff -r eec0210589b3 -r bb82a2982d3d test-data/pearson_small_50kb.h5
Binary file test-data/pearson_small_50kb.h5 has changed
diff -r eec0210589b3 -r bb82a2982d3d test-data/pearson_small_50kb_transform.cool
Binary file test-data/pearson_small_50kb_transform.cool has changed
diff -r eec0210589b3 -r bb82a2982d3d test-data/raw_qc_report
--- a/test-data/raw_qc_report	Tue Jan 02 10:12:46 2018 -0500
+++ b/test-data/raw_qc_report	Wed Mar 07 03:41:30 2018 -0500
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