Mercurial > repos > bimib > cobraxy

comparison COBRAxy/local/svg metabolic maps/HMRcore_map.svg @ 4:41f35c2f0c7b draft

Find changesets by keywords (author, files, the commit message), revision number or hash, or revset expression.
Uploaded
author luca_milaz
date Wed, 18 Sep 2024 10:59:10 +0000
parents
children
comparison
equal deleted inserted replaced
3:1f3ac6fd9867 4:41f35c2f0c7b
1 <?xml version="1.0" encoding="UTF-8" standalone="no"?>
2 <!-- Generator: Adobe Illustrator 22.0.1, SVG Export Plug-In . SVG Version: 6.00 Build 0) -->
3
4 <svg
5 xmlns:dc="http://purl.org/dc/elements/1.1/"
6 xmlns:cc="http://creativecommons.org/ns#"
7 xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
8 xmlns:svg="http://www.w3.org/2000/svg"
9 xmlns="http://www.w3.org/2000/svg"
10 xmlns:xlink="http://www.w3.org/1999/xlink"
11 xmlns:sodipodi="http://sodipodi.sourceforge.net/DTD/sodipodi-0.dtd"
12 xmlns:inkscape="http://www.inkscape.org/namespaces/inkscape"
13 version="1.1"
14 x="0px"
15 y="0px"
16 viewBox="0 0 1904.8016 1511.2752"
17 xml:space="preserve"
18 id="svg2"
19 inkscape:version="0.91 r13725"
20 sodipodi:docname="HMRcoreMap.svg"
21 width="1904.8015"
22 height="1511.2753"><metadata
23 id="metadata2021"><rdf:RDF><cc:Work
24 rdf:about=""><dc:format>image/svg+xml</dc:format><dc:type
25 rdf:resource="http://purl.org/dc/dcmitype/StillImage" /><dc:title /></cc:Work></rdf:RDF></metadata><defs
26 id="defs2019"><sodipodi:namedview
27 showguides="true"
28 showgrid="true"
29 pagecolor="#ffffff"
30 inkscape:zoom="1.4702451"
31 inkscape:window-y="-8"
32 inkscape:window-x="-8"
33 inkscape:window-width="1920"
34 inkscape:window-maximized="1"
35 inkscape:window-height="1017"
36 inkscape:snap-page="false"
37 inkscape:snap-grids="true"
38 inkscape:pageshadow="2"
39 inkscape:pageopacity="0.0"
40 inkscape:document-units="px"
41 inkscape:cy="338.10986"
42 inkscape:cx="1343.7768"
43 inkscape:current-layer="layer1"
44 id="base"
45 fit-margin-top="0"
46 fit-margin-right="0"
47 fit-margin-left="0"
48 fit-margin-bottom="0"
49 borderopacity="1.0"
50 bordercolor="#666666"><inkscape:grid
51 type="xygrid"
52 originy="72.926308"
53 originx="-97.409688"
54 id="grid3434"
55 dotted="true" /></sodipodi:namedview></defs><sodipodi:namedview
56 pagecolor="#ffffff"
57 bordercolor="#666666"
58 borderopacity="1"
59 objecttolerance="10"
60 gridtolerance="10"
61 guidetolerance="10"
62 inkscape:pageopacity="0"
63 inkscape:pageshadow="2"
64 inkscape:window-width="1920"
65 inkscape:window-height="1017"
66 id="namedview2017"
67 showgrid="false"
68 inkscape:zoom="0.44727204"
69 inkscape:cx="497.63252"
70 inkscape:cy="796.80241"
71 inkscape:window-x="-8"
72 inkscape:window-y="-8"
73 inkscape:window-maximized="1"
74 inkscape:current-layer="svg2"
75 fit-margin-top="0"
76 fit-margin-left="0"
77 fit-margin-right="0"
78 fit-margin-bottom="0" /><style
79 type="text/css"
80 id="style4">
81 .st0{display:none;}
82 .st1{display:inline;}
83 .st2{fill:none;stroke:#5AB6E7;stroke-width:7;stroke-linejoin:round;}
84 .st3{fill:none;stroke:#5AB6E7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:11.9422,11.9422;}
85 .st4{fill:none;stroke:#5AB6E7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:12.1815,12.1815;}
86 .st5{font-family:'Helvetica';}
87 .st6{font-size:30px;}
88 .st7{font-size:39.262px;}
89 .st8{fill:none;stroke:#0000FF;stroke-width:30;}
90 .st9{fill:none;stroke:#E41A1C;stroke-width:30;}
91 .st10{fill:none;stroke:#BEBEBE;stroke-width:30;}
92 .st11{stroke:#000000;stroke-width:30;}
93 .st12{fill:none;stroke:#BEBEBE;stroke-width:30;stroke-dasharray:30,30;stroke-dashoffset:6;}
94 .st13{fill:none;stroke:#000000;stroke-width:1.8444;}
95 .st14{fill:none;stroke:#000000;stroke-width:2.1821;}
96 .st15{font-family:'Calibri-Bold';}
97 .st16{font-size:16px;}
98 .st17{font-family:'Calibri';}
99 .st18{font-size:10px;}
100 .st19{fill:none;stroke:#000000;stroke-width:1.8856;}
101 .st20{fill:none;stroke:#000000;stroke-width:1.9459;}
102 .st21{fill:none;stroke:#000000;stroke-width:2.2892;}
103 .st22{fill:none;stroke:#000000;stroke-width:2.5;}
104 .st23{fill:none;stroke:#000000;stroke-width:1.9412;}
105 .st24{fill:none;stroke:#000000;stroke-width:1.9661;}
106 .st25{fill:none;stroke:#000000;stroke-width:1.0869;}
107 .st26{font-size:6.0937px;}
108 .st27{fill:none;stroke:#000000;stroke-width:2.0174;}
109 .st28{fill:none;stroke:#000000;stroke-width:1.889;}
110 .st29{fill:none;stroke:#000000;stroke-width:1.7769;}
111 .st30{fill:none;stroke:#000000;stroke-width:1.8717;}
112 .st31{fill:none;stroke:#000000;stroke-width:1.6971;}
113 .st32{fill:none;stroke:#000000;stroke-width:2.4492;}
114 .st33{fill:none;stroke:#000000;stroke-width:2.0366;}
115 .st34{fill:none;stroke:#000000;stroke-width:1.5903;}
116 .st35{fill:none;stroke:#000000;stroke-width:1.7287;}
117 .st36{fill:none;stroke:#000000;stroke-width:1.7741;}
118 .st37{fill:none;stroke:#000000;stroke-width:2.2309;}
119 .st38{font-size:14px;}
120 .st39{fill:none;stroke:#000000;stroke-width:1.7752;}
121 .st40{font-size:9.75px;}
122 .st41{fill:none;stroke:#000000;stroke-width:1.8816;}
123 .st42{fill:none;stroke:#000000;stroke-width:1.8615;}
124 .st43{fill:none;stroke:#000000;stroke-width:1.7923;}
125 .st44{fill:none;stroke:#000000;stroke-width:1.8691;}
126 .st45{fill:none;stroke:#000000;stroke-width:2.823;}
127 .st46{fill:none;stroke:#000000;stroke-width:2.3556;}
128 .st47{fill:none;stroke:#000000;stroke-width:2.0484;}
129 .st48{fill:none;stroke:#000000;stroke-width:1.127;}
130 .st49{fill:none;stroke:#000000;stroke-width:1.5383;}
131 .st50{fill:none;stroke:#000000;stroke-width:1.4921;}
132 .st51{fill:none;stroke:#000000;stroke-width:1.4117;}
133 .st52{fill:none;stroke:#000000;stroke-width:1.3787;}
134 .st53{fill:none;stroke:#000000;stroke-width:2.2437;}
135 .st54{fill:none;stroke:#000000;stroke-width:1.8492;}
136 .st55{fill:none;stroke:#000000;stroke-width:1.816;}
137 .st56{fill:none;stroke:#000000;stroke-width:2.0159;}
138 .st57{fill:none;stroke:#000000;stroke-width:2.0089;}
139 .st58{fill:none;stroke:#000000;stroke-width:1.2666;}
140 .st59{fill:none;stroke:#000000;stroke-width:1.3186;}
141 .st60{fill:none;stroke:#000000;stroke-width:1.2211;}
142 .st61{fill:none;stroke:#000000;stroke-width:1.1828;}
143 .st62{fill:none;stroke:#000000;stroke-width:2.0699;}
144 .st63{fill:none;stroke:#000000;stroke-width:2.1781;}
145 .st64{fill:none;stroke:#000000;stroke-width:2.6751;}
146 .st65{fill:none;stroke:#000000;stroke-width:3.1636;}
147 .st66{fill:none;stroke:#000000;stroke-width:3.3699;}
148 .st67{fill:none;stroke:#000000;stroke-width:2.3147;}
149 .st68{fill:none;stroke:#000000;stroke-width:2.2203;}
150 .st69{fill:none;stroke:#000000;stroke-width:2.2293;}
151 .st70{fill:none;stroke:#000000;stroke-width:1.9667;}
152 .st71{fill:none;stroke:#000000;stroke-width:2.1341;}
153 .st72{fill:none;stroke:#000000;stroke-width:1.5819;}
154 .st73{fill:none;stroke:#000000;stroke-width:2.0995;}
155 .st74{fill:none;stroke:#000000;stroke-width:2.4348;}
156 .st75{fill:none;stroke:#000000;stroke-width:2.3313;}
157 .st76{fill:none;stroke:#000000;stroke-width:2.0948;}
158 .st77{fill:none;stroke:#000000;stroke-width:2.2352;}
159 .st78{fill:none;stroke:#000000;stroke-width:2.3817;}
160 .st79{fill:none;stroke:#000000;stroke-width:2.2976;}
161 .st80{fill:none;stroke:#000000;stroke-width:2.0951;}
162 .st81{fill:none;stroke:#231F20;stroke-width:7;stroke-linejoin:round;stroke-miterlimit:2;}
163 .st82{fill:none;stroke:#000000;stroke-width:1.3247;}
164 .st83{fill:none;stroke:#000000;stroke-width:1.564;}
165 .st84{fill:none;stroke:#000000;stroke-width:2.1156;}
166 .st85{fill:none;stroke:#000000;stroke-width:1.3926;}
167 .st86{fill:none;stroke:#000000;stroke-width:1.123;}
168 .st87{font-size:9.7577px;}
169 .st88{font-size:15.6123px;}
170 .st89{fill:none;stroke:#000000;stroke-width:2.0926;}
171 .st90{fill:none;stroke:#000000;stroke-width:1.7671;}
172 .st91{fill:none;stroke:#000000;stroke-width:1.7901;}
173 .st92{fill:none;stroke:#000000;stroke-width:1.9212;}
174 .st93{fill:none;stroke:#000000;stroke-width:1.3319;}
175 .st94{fill:none;stroke:#000000;stroke-width:2.1398;}
176 .st95{fill:none;stroke:#000000;stroke-width:1.3641;}
177 .st96{fill:none;stroke:#000000;stroke-width:2.216;}
178 .st97{fill:none;stroke:#000000;stroke-width:2.341;}
179 .st98{fill:none;stroke:#000000;stroke-width:1.2412;}
180 .st99{fill:none;stroke:#000000;stroke-width:1.7827;}
181 .st100{fill:none;stroke:#000000;stroke-width:1.8658;}
182 .st101{fill:none;stroke:#000000;stroke-width:2.4932;}
183 .st102{fill:none;stroke:#000000;stroke-width:2.489;}
184 .st103{fill:none;stroke:#000000;stroke-width:2.5188;}
185 .st104{fill:none;stroke:#000000;stroke-width:2.4962;}
186 .st105{fill:none;stroke:#000000;stroke-width:1.6791;}
187 .st106{fill:none;stroke:#000000;stroke-width:1.8121;}
188 .st107{fill:none;stroke:#000000;stroke-width:1.5802;}
189 .st108{fill:none;stroke:#000000;stroke-width:1.5346;}
190 .st109{fill:none;stroke:#000000;stroke-width:1.8293;}
191 .st110{fill:none;stroke:#000000;stroke-width:1.6126;}
192 .st111{fill:none;stroke:#000000;stroke-width:2.5434;}
193 .st112{fill:none;stroke:#000000;stroke-width:1.7519;}
194 .st113{fill:none;stroke:#000000;stroke-width:1.5283;}
195 .st114{fill:none;stroke:#000000;stroke-width:1.8016;}
196 .st115{fill:none;stroke:#000000;stroke-width:3.1376;}
197 .st116{fill:none;stroke:#000000;stroke-width:1.8065;}
198 .st117{fill:none;stroke:#000000;stroke-width:2.1653;}
199 .st118{fill:none;stroke:#000000;stroke-width:1.5857;}
200 .st119{fill:none;stroke:#000000;stroke-width:2.1349;}
201 .st120{fill:none;stroke:#000000;stroke-width:2.3204;}
202 .st121{fill:none;stroke:#000000;stroke-width:1.6814;}
203 .st122{fill:none;stroke:#000000;stroke-width:2.9048;}
204 .st123{fill:none;stroke:#000000;stroke-width:2.2582;}
205 .st124{fill:none;stroke:#000000;stroke-width:1.9206;}
206 .st125{fill:none;stroke:#000000;stroke-width:2.0975;}
207 .st126{fill:none;stroke:#000000;stroke-width:1.1759;}
208 .st127{fill:none;stroke:#000000;stroke-width:1.1348;}
209 .st128{fill:none;stroke:#000000;stroke-width:2.0031;}
210 .st129{fill:none;stroke:#000000;stroke-width:1.966;}
211 .st130{fill:none;stroke:#000000;stroke-width:1.822;}
212 .st131{fill:none;stroke:#000000;stroke-width:2.3785;}
213 .st132{fill:none;stroke:#000000;stroke-width:1.5336;}
214 .st133{fill:none;stroke:#000000;stroke-width:1.4989;}
215 .st134{fill:none;stroke:#000000;stroke-width:1.8163;}
216 .st135{fill:none;stroke:#000000;stroke-width:2.0955;}
217 .st136{fill:none;stroke:#000000;stroke-width:2.1429;}
218 .st137{fill:none;stroke:#000000;stroke-width:2.1034;}
219 .st138{fill:none;stroke:#000000;stroke-width:2.0686;}
220 .st139{fill:none;stroke:#000000;stroke-width:1.1187;}
221 .st140{fill:none;stroke:#000000;stroke-width:2.3278;}
222 .st141{fill:none;stroke:#000000;stroke-width:2.1814;}
223 .st142{fill:none;stroke:#000000;stroke-width:2.0648;}
224 .st143{fill:none;stroke:#000000;stroke-width:2.5236;}
225 .st144{fill:none;stroke:#000000;stroke-width:2.5697;}
226 .st145{fill:#786721;stroke:#000000;stroke-width:2.5;}
227 .st146{fill:none;stroke:#000000;stroke-width:1.4509;}
228 .st147{fill:none;stroke:#000000;stroke-width:1.7529;}
229 .st148{fill:none;stroke:#000000;stroke-width:1.9252;}
230 .st149{fill:none;stroke:#000000;stroke-width:1.8983;}
231 .st150{fill:none;stroke:#000000;stroke-width:1.7735;}
232 .st151{fill:none;stroke:#000000;stroke-width:1.5537;}
233 .st152{fill:none;stroke:#000000;stroke-width:1.7117;}
234 .st153{fill:none;stroke:#000000;stroke-width:1.7429;}
235 .st154{fill:none;stroke:#000000;stroke-width:1.639;}
236 .st155{fill:none;stroke:#000000;stroke-width:2.4155;}
237 .st156{fill:none;stroke:#000000;stroke-width:1.9672;}
238 .st157{fill:none;stroke:#000000;stroke-width:2.2231;}
239 .st158{fill:none;stroke:#000000;stroke-width:1.8337;}
240 .st159{fill:none;stroke:#000000;stroke-width:1.8531;}
241 .st160{fill:none;stroke:#000000;stroke-width:2.2256;}
242 .st161{fill:none;stroke:#000000;stroke-width:2.0666;}
243 .st162{fill:none;stroke:#000000;stroke-width:1.7335;}
244 .st163{fill:none;stroke:#000000;stroke-width:1.6847;}
245 .st164{fill:none;stroke:#000000;stroke-width:2.4884;}
246 .st165{fill:none;stroke:#000000;stroke-width:2.3113;}
247 .st166{fill:none;stroke:#000000;stroke-width:2.1555;}
248 .st167{fill:none;stroke:#000000;stroke-width:1.9909;}
249 .st168{fill:none;stroke:#000000;stroke-width:9.2205;stroke-linecap:round;stroke-linejoin:round;stroke-miterlimit:2;}
250 .st169{fill:none;stroke:#000000;stroke-width:2.5668;}
251 .st170{fill:none;stroke:#000000;stroke-width:1.9328;}
252 .st171{fill:none;stroke:#000000;stroke-width:3.1971;}
253 .st172{fill:none;stroke:#000000;stroke-width:3.1373;}
254 .st173{font-size:6.5px;}
255 </style><g
256 id="Layer_2"
257 transform="translate(-20.6,18.418554)"><g
258 id="rect3188_1_"
259 class="st0"
260 style="display:none"><g
261 class="st1"
262 id="g8"
263 style="display:inline"><polyline
264 class="st2"
265 points="269.1,669.8 269.1,663.8 275.1,663.8 "
266 id="polyline10"
267 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
268 class="st3"
269 x1="287"
270 y1="663.79999"
271 x2="1475.2"
272 y2="663.79999"
273 id="line12"
274 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:11.9422, 11.9422" /><polyline
275 class="st2"
276 points="1481.2,663.8 1487.2,663.8 1487.2,669.8 "
277 id="polyline14"
278 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
279 class="st4"
280 x1="1487.2"
281 y1="682"
282 x2="1487.2"
283 y2="1138.8"
284 id="line16"
285 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:12.1815, 12.1815" /><polyline
286 class="st2"
287 points="1487.2,1144.9 1487.2,1150.9 1481.2,1150.9 "
288 id="polyline18"
289 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
290 class="st3"
291 x1="1469.3"
292 y1="1150.9"
293 x2="281"
294 y2="1150.9"
295 id="line20"
296 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:11.9422, 11.9422" /><polyline
297 class="st2"
298 points="275.1,1150.9 269.1,1150.9 269.1,1144.9 "
299 id="polyline22"
300 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
301 class="st4"
302 x1="269.10001"
303 y1="1132.7"
304 x2="269.10001"
305 y2="675.90002"
306 id="line24"
307 style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:12.1815, 12.1815" /></g></g></g><g
308 id="flowRoot3336"
309 transform="translate(-20.6,18.418554)" /><g
310 id="flowRoot16808"
311 transform="translate(-20.6,18.418554)" /><g
312 id="flowRoot2749"
313 transform="translate(-20.6,18.418554)" /><g
314 id="flowRoot3621"
315 transform="translate(-20.6,18.418554)" /><g
316 id="flowRoot1974"
317 transform="translate(-20.6,18.418554)" /><text
318 style="font-size:30px;font-family:Helvetica"
319 id="text35"
320 class="st5 st6"
321 x="129.77209"
322 y="1429.6542">= Up regulated</text>
323 <text
324 style="font-size:30px;font-family:Helvetica"
325 id="text37"
326 class="st5 st6"
327 x="129.77209"
328 y="1504.6542">= Down regulated</text>
329 <text
330 style="font-size:39.26200104px;font-family:Helvetica"
331 id="text39"
332 class="st5 st7"
333 x="-1.9770008"
334 y="1365.1874">Legend</text>
335 <path
336 style="fill:none;stroke:#0000ff;stroke-width:30"
337 d="m 0,1495.6186 112,0"
338 class="st8"
339 inkscape:connector-curvature="0"
340 id="path6613-3" /><path
341 style="fill:none;stroke:#e41a1c;stroke-width:30"
342 d="m 0,1420.7186 112,0"
343 class="st9"
344 inkscape:connector-curvature="0"
345 id="path6613-8-6" /><path
346 style="fill:none;stroke:#bebebe;stroke-width:30"
347 d="m 503.8,1492.0186 112,0"
348 class="st10"
349 inkscape:connector-curvature="0"
350 id="path6613-8-1-0" /><path
351 style="stroke:#000000;stroke-width:30"
352 d="m 1140.7,1415.1186 112,0"
353 class="st11"
354 inkscape:connector-curvature="0"
355 id="path6613-8-4-9" /><path
356 style="fill:none;stroke:#bebebe;stroke-width:30;stroke-dasharray:30, 30;stroke-dashoffset:6"
357 d="m 503.8,1417.3186 112,0"
358 class="st12"
359 inkscape:connector-curvature="0"
360 id="path6613-8-2-6" /><text
361 style="font-size:30px;font-family:Helvetica"
362 id="text46"
363 class="st5 st6"
364 x="1270.1295"
365 y="1423.1249">= Not classified</text>
366 <text
367 style="font-size:30px;font-family:Helvetica"
368 id="text48"
369 class="st5 st6"
370 x="631.3902"
371 y="1426.3895">= Not significant</text>
372 <text
373 style="font-size:30px;font-family:Helvetica"
374 id="text50"
375 class="st5 st6"
376 x="631.3902"
377 y="1501.3895">= Fold change under threshold</text>
378 <text
379 style="font-size:30px;font-family:Helvetica"
380 id="text52"
381 class="st5 st6"
382 x="1139.6979"
383 y="1499.9501">Thickness is proportional to fold change</text>
384 <path
385 style="fill:none;stroke:#000000;stroke-width:1.84440005"
386 d="m 834.5,332.71855 26.9,-0.1 m -18,-9 c -2.8,5.8 3.1,9.6 3.1,9.6 m 3.1,-0.5 c 5.1,-0.7 4.9,-9.1 4.9,-9.1"
387 class="st13"
388 inkscape:label="CMPK1_DTYMK"
389 inkscape:connector-curvature="0"
390 id="R_CMPK1_DTYMK" /><path
391 style="fill:none;stroke:#000000;stroke-width:2.18210006"
392 d="m 464.9,461.41855 c 2.2,-7.3 2.2,-7.3 2.2,-7.3 l 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
393 class="st14"
394 inkscape:label="backward PGM"
395 inkscape:connector-curvature="0"
396 id="B_PGAM2_PGAM1_BPGM_PGAM4_1" /><text
397 style="font-size:16px;font-family:Calibri-Bold"
398 id="text56"
399 class="st15 st16"
400 x="449.63071"
401 y="207.37375">F6P</text>
402 <text
403 style="font-size:16px;font-family:Calibri-Bold"
404 id="text58"
405 class="st15 st16"
406 x="443.9202"
407 y="262.58224">F16BP</text>
408 <text
409 style="font-size:16px;font-family:Calibri-Bold"
410 id="text60"
411 class="st15 st16"
412 x="446.7605"
413 y="320.19556">GA3P</text>
414 <text
415 style="font-size:16px;font-family:Calibri-Bold"
416 id="text62"
417 class="st15 st16"
418 x="435.38208"
419 y="383.34305">1,3BPGA</text>
420 <text
421 style="font-size:16px;font-family:Calibri-Bold"
422 id="text64"
423 class="st15 st16"
424 x="453.15561"
425 y="449.14966">3PG</text>
426 <text
427 style="font-size:16px;font-family:Calibri-Bold"
428 id="text66"
429 class="st15 st16"
430 x="449.81769"
431 y="507.42996">2PG</text>
432 <text
433 style="font-size:16px;font-family:Calibri-Bold"
434 id="text68"
435 class="st15 st16"
436 x="453.76788"
437 y="562.48846">PEP</text>
438 <text
439 style="font-size:16px;font-family:Calibri-Bold"
440 id="text70"
441 class="st15 st16"
442 x="456.6004"
443 y="614.97485">Pyr</text>
444 <text
445 style="font-size:16px;font-family:Calibri-Bold"
446 id="text72"
447 class="st15 st16"
448 x="349.18579"
449 y="614.4632">Lact</text>
450 <text
451 style="font-size:10px;font-family:Calibri"
452 id="text74"
453 class="st17 st18"
454 x="483.3494"
455 y="222.37965">ATP</text>
456 <text
457 style="font-size:10px;font-family:Calibri"
458 id="text76"
459 class="st17 st18"
460 x="484.75418"
461 y="235.29225">ADP</text>
462 <text
463 style="font-size:10px;font-family:Calibri"
464 id="text78"
465 class="st17 st18"
466 x="478.8587"
467 y="337.66135">NAD</text>
468 <text
469 style="font-size:10px;font-family:Calibri"
470 id="text80"
471 class="st17 st18"
472 x="497.25217"
473 y="337.66135">+</text>
474 <text
475 style="font-size:10px;font-family:Calibri"
476 id="text82"
477 class="st17 st18"
478 x="502.2327"
479 y="337.66135">Pi</text>
480 <text
481 style="font-size:10px;font-family:Calibri"
482 id="text84"
483 class="st17 st18"
484 x="481.2063"
485 y="350.90945">NADH+H</text>
486 <text
487 style="font-size:10px;font-family:Calibri"
488 id="text86"
489 class="st17 st18"
490 x="481.4881"
491 y="401.51096">ADP</text>
492 <text
493 style="font-size:10px;font-family:Calibri"
494 id="text88"
495 class="st17 st18"
496 x="482.81668"
497 y="413.79224">ATP</text>
498 <text
499 style="font-size:10px;font-family:Calibri"
500 id="text90"
501 class="st17 st18"
502 x="481.35968"
503 y="575.7132">ADP</text>
504 <text
505 style="font-size:10px;font-family:Calibri"
506 id="text92"
507 class="st17 st18"
508 x="485.36938"
509 y="586.74536">ATP</text>
510 <path
511 style="fill:none;stroke:#000000;stroke-width:2.18210006"
512 d="m 460,182.91855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
513 class="st14"
514 inkscape:label="forward GPI "
515 inkscape:connector-curvature="0"
516 id="F_GPI" /><path
517 style="fill:none;stroke:#000000;stroke-width:1.88559997"
518 d="m 462.1,159.61855 c 0,23.8 0,23.8 0,23.8"
519 class="st19"
520 inkscape:label="GPI "
521 inkscape:connector-curvature="0"
522 id="R_GPI" /><path
523 style="fill:none;stroke:#000000;stroke-width:1.94589996"
524 d="m 467.2,458.91855 c 0,25.4 0,25.4 0,25.4"
525 class="st20"
526 inkscape:label="phosphoglycerate mutase"
527 inkscape:connector-curvature="0"
528 id="R_PGAM2_PGAM1_BPGM_PGAM4_1" /><path
529 style="fill:none;stroke:#000000;stroke-width:2.18210006"
530 d="m 465.1,482.61855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
531 class="st14"
532 inkscape:label="forward PGM"
533 inkscape:connector-curvature="0"
534 id="F_PGAM2_PGAM1_BPGM_PGAM4_1" /><path
535 style="fill:none;stroke:#000000;stroke-width:2.18210006"
536 d="m 464.9,516.91855 c 2.2,-7.3 2.2,-7.3 2.2,-7.3 l 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
537 class="st14"
538 inkscape:label="backward enolase"
539 inkscape:connector-curvature="0"
540 id="B_ENO1_ENO3_ENO2" /><text
541 style="font-size:16px;font-family:Calibri-Bold"
542 id="text99"
543 class="st15 st16"
544 x="492.44656"
545 y="284.29803">DHAP</text>
546 <path
547 style="fill:none;stroke:#000000;stroke-width:2.28920007"
548 d="m 462.7,265.81855 c 0,31.9 0,31.9 0,31.9 m 0.6,-17.7 20.2,0"
549 class="st21"
550 inkscape:connector-curvature="0"
551 id="R_ALDOC_ALDOB_ALDOA_2" /><path
552 style="fill:none;stroke:#000000;stroke-width:2.5"
553 d="m 482.4,278.01855 c 6.1,2.2 6.1,2.2 6.1,2.2 l -6.1,2.2 1.5,-2.2 -1.5,-2.2 z m -21.6,17.9 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
554 class="st22"
555 inkscape:connector-curvature="0"
556 id="F_ALDOC_ALDOB_ALDOA_2" /><path
557 style="fill:none;stroke:#000000;stroke-width:1.94120002"
558 d="m 503.2,293.81855 2.4,-4 0.8,-1.3 -4.9,2.1 1.9,0.6 -0.2,2.6 z"
559 class="st23"
560 sodipodi:nodetypes="cccccc"
561 inkscape:label="backward TPI1_TPI1P2 "
562 inkscape:connector-curvature="0"
563 id="B_TPI1_TPI1P2" /><path
564 style="fill:none;stroke:#000000;stroke-width:1.96609998"
565 d="m 488.7,300.71855 c -3.2,5.4 -3.2,5.4 -3.2,5.4 l 5,-2.3 -1.9,-0.6 0.1,-2.5 z"
566 class="st24"
567 inkscape:label="forwardTPI1_TPI1P2 "
568 inkscape:connector-curvature="0"
569 id="F_TPI1_TPI1P2" /><path
570 style="fill:none;stroke:#000000;stroke-width:1.0869"
571 d="m 502.6,291.71855 -14.9,13"
572 class="st25"
573 inkscape:label="TPI1_TPI1P2 "
574 inkscape:connector-curvature="0"
575 id="R_TPI1_TPI1P2" /><text
576 style="font-size:10px;font-family:Calibri"
577 id="text106"
578 class="st17 st18"
579 x="485.7688"
580 y="533.16919">H</text>
581 <text
582 style="font-size:6.09369993px;font-family:Calibri"
583 id="text108"
584 class="st17 st26"
585 x="491.9993"
586 y="535.16919">2</text>
587 <text
588 style="font-size:10px;font-family:Calibri"
589 id="text110"
590 class="st17 st18"
591 x="495.08768"
592 y="533.16919">O</text>
593 <text
594 style="font-size:10px;font-family:Calibri"
595 id="text112"
596 class="st17 st18"
597 x="391.7298"
598 y="593.52759">NAD</text>
599 <text
600 style="font-size:16px;font-family:Calibri-Bold"
601 id="text114"
602 class="st15 st16"
603 x="532.302"
604 y="158.84834">6Pgl</text>
605 <text
606 style="font-size:10px;font-family:Calibri"
607 id="text116"
608 class="st17 st18"
609 x="471.15601"
610 y="174.58125">NADP</text>
611 <text
612 style="font-size:16px;font-family:Calibri-Bold"
613 id="text118"
614 class="st15 st16"
615 x="598.32654"
616 y="159.01485">6PDG</text>
617 <text
618 style="font-size:10px;font-family:Calibri"
619 id="text120"
620 class="st17 st18"
621 x="627.64771"
622 y="176.58224">NADP</text>
623 <text
624 style="font-size:16px;font-family:Calibri-Bold"
625 id="text122"
626 class="st15 st16"
627 x="694.76404"
628 y="159.07295">Ru5P</text>
629 <text
630 style="font-size:16px;font-family:Calibri-Bold"
631 id="text124"
632 class="st15 st16"
633 x="777.18494"
634 y="174.95485">R5P</text>
635 <text
636 style="font-size:10px;font-family:Calibri"
637 id="text126"
638 class="st17 st18"
639 x="754.10773"
640 y="199.29225">AMP</text>
641 <text
642 style="font-size:10px;font-family:Calibri"
643 id="text128"
644 class="st17 st18"
645 x="760.08435"
646 y="185.74825">ATP</text>
647 <path
648 style="fill:none;stroke:#000000;stroke-width:2.01740003"
649 d="m 588.2,152.11855 c 7.3,2.2 7.3,2.2 7.3,2.2 l -7.3,2.2 1.8,-2.2 -1.8,-2.2 z"
650 class="st27"
651 inkscape:label="forward H6PD_PGLS "
652 inkscape:connector-curvature="0"
653 id="F_H6PD_PGLS" /><text
654 style="font-size:10px;font-family:Calibri"
655 id="text131"
656 class="st17 st18"
657 x="564.25323"
658 y="173.96214">H</text>
659 <text
660 style="font-size:6.09369993px;font-family:Calibri"
661 id="text133"
662 class="st17 st26"
663 x="570.4837"
664 y="175.96214">2</text>
665 <text
666 style="font-size:10px;font-family:Calibri"
667 id="text135"
668 class="st17 st18"
669 x="573.57251"
670 y="173.96214">O</text>
671 <text
672 style="font-size:16px;font-family:Calibri-Bold"
673 id="text137"
674 class="st15 st16"
675 x="774.87531"
676 y="143.11105">Xil5P</text>
677 <path
678 style="fill:none;stroke:#000000;stroke-width:1.88900006"
679 d="m 814.5,167.11855 c -5.3,2.4 -5.3,2.4 -5.3,2.4 l 2.8,-4.7 0.2,2 2.3,0.3 z m -1.4,-20.6 c -2.5,-4.8 -2.5,-4.8 -2.5,-4.8 l 5.1,2.6 -2.3,0.2 -0.3,2 z"
680 class="st28"
681 inkscape:label="forward TKTL1_TKTL2_TKT_2"
682 inkscape:connector-curvature="0"
683 id="F_TKTL1_TKTL2_TKT_2" /><path
684 style="fill:none;stroke:#000000;stroke-width:1.88900006"
685 d="m 834,143.41855 c 5.2,-2.5 5.2,-2.5 5.2,-2.5 l -2.6,4.7 -0.3,-2 -2.3,-0.2 z m 3.8,21.6 c 2.6,4.8 2.6,4.8 2.6,4.8 l -5.2,-2.6 2.3,-0.2 0.3,-2 z"
686 class="st28"
687 inkscape:label="backward TKTL1_TKTL2_TKT_2 "
688 inkscape:connector-curvature="0"
689 id="B_TKTL1_TKTL2_TKT_2" /><path
690 style="fill:none;stroke:#000000;stroke-width:1.77690005"
691 d="m 813,144.01855 23.9,22.6 0,0 m -24.8,0.5 23.9,-22.6"
692 class="st29"
693 inkscape:label="TKTL1_TKTL2_TKT_2 "
694 inkscape:connector-curvature="0"
695 id="R_TKTL1_TKTL2_TKT_2" /><text
696 style="font-size:16px;font-family:Calibri-Bold"
697 id="text142"
698 class="st15 st16"
699 x="842.75421"
700 y="140.81226">Sed7P</text>
701 <text
702 style="font-size:16px;font-family:Calibri-Bold"
703 id="text144"
704 class="st15 st16"
705 x="844.42902"
706 y="174.28685">GA3P</text>
707 <path
708 style="fill:none;stroke:#000000;stroke-width:1.87170005"
709 d="m 890,164.31855 c -5.3,2.3 -5.3,2.3 -5.3,2.3 l 2.8,-4.5 0.2,2 2.3,0.2 z m -1.4,-20.1 c -2.5,-4.7 -2.5,-4.7 -2.5,-4.7 l 5.1,2.6 -2.3,0.1 -0.3,2 z"
710 class="st30"
711 inkscape:label="backward TALDO1 "
712 inkscape:connector-curvature="0"
713 id="B_TALDO1" /><path
714 style="fill:none;stroke:#000000;stroke-width:1.87170005"
715 d="m 912.3,141.61855 c 5.2,-2.4 5.2,-2.4 5.2,-2.4 l -2.7,4.6 -0.3,-2 -2.2,-0.2 z m 3.9,21.1 c 2.6,4.6 2.6,4.6 2.6,4.6 l -5.2,-2.5 2.3,-0.2 0.3,-1.9 z"
716 class="st30"
717 inkscape:label="forward TALDO1 "
718 inkscape:connector-curvature="0"
719 id="F_TALDO1" /><path
720 style="fill:none;stroke:#000000;stroke-width:1.87170005"
721 d="m 888.1,141.41855 26.3,22.8 0,0 m -27.2,0.6 26.3,-22.8"
722 class="st30"
723 inkscape:label="TALDO1 "
724 inkscape:connector-curvature="0"
725 id="R_TALDO1" /><text
726 style="font-size:16px;font-family:Calibri-Bold"
727 id="text149"
728 class="st15 st16"
729 x="922.31085"
730 y="174.11154">Ery4P</text>
731 <text
732 style="font-size:16px;font-family:Calibri-Bold"
733 id="text151"
734 class="st15 st16"
735 x="921.73865"
736 y="140.67255">F6P</text>
737 <path
738 style="fill:none;stroke:#000000;stroke-width:1.69710004"
739 d="m 967.5,191.21855 c -5.2,1.9 -5.2,1.9 -5.2,1.9 l 2.7,-3.8 0.2,1.7 2.3,0.2 z m -1.3,-16.9 c -2.4,-3.9 -2.4,-3.9 -2.4,-3.9 l 5,2.2 -2.2,0.1 -0.4,1.6 z"
740 class="st31"
741 inkscape:label="forward TKTL1_TKTL2_TKT_1 "
742 inkscape:connector-curvature="0"
743 id="F_TKTL1_TKTL2_TKT_1" /><path
744 style="fill:none;stroke:#000000;stroke-width:1.69710004"
745 d="m 989.2,172.21855 c 5.1,-2 5.1,-2 5.1,-2 l -2.6,3.9 -0.3,-1.7 -2.2,-0.2 z m 3.8,17.8 c 2.5,3.9 2.5,3.9 2.5,3.9 l -5.1,-2.1 2.2,-0.2 0.4,-1.6 z"
746 class="st31"
747 inkscape:label="backward TKTL1_TKTL2_TKT_1 "
748 inkscape:connector-curvature="0"
749 id="B_TKTL1_TKTL2_TKT_1" /><path
750 style="fill:none;stroke:#000000;stroke-width:1.69710004"
751 d="m 965.6,172.01855 25.6,19.2 0,0 m -26.5,0.5 25.6,-19.2"
752 class="st31"
753 inkscape:label="TKTL1_TKTL2_TKT_1 "
754 inkscape:connector-curvature="0"
755 id="R_TKTL1_TKTL2_TKT_1" /><text
756 style="font-size:16px;font-family:Calibri-Bold"
757 id="text156"
758 class="st15 st16"
759 x="997.87823"
760 y="172.36835">GA3P</text>
761 <text
762 style="font-size:16px;font-family:Calibri-Bold"
763 id="text158"
764 class="st15 st16"
765 x="998.20343"
766 y="200.00905">F6P</text>
767 <text
768 style="font-size:16px;font-family:Calibri-Bold"
769 id="text160"
770 class="st15 st16"
771 x="924.83331"
772 y="199.35765">Xil5P</text>
773 <text
774 style="font-size:16px;font-family:Calibri-Bold"
775 id="text162"
776 class="st15 st16"
777 x="899.55011"
778 y="119.60376">Sed1,7BP</text>
779 <text
780 style="font-size:10px;font-family:Calibri"
781 id="text164"
782 class="st17 st18"
783 x="862.2395"
784 y="101.52756">ATP</text>
785 <text
786 style="font-size:10px;font-family:Calibri"
787 id="text166"
788 class="st17 st18"
789 x="878.388"
790 y="101.37626">ADP</text>
791 <path
792 style="fill:none;stroke:#000000;stroke-width:2.44919991"
793 d="m 974.2,113.01855 c -7.1,2.6 -7.1,2.6 -7.1,2.6 l 7.3,1.8 -2,-2 1.8,-2.4 z"
794 class="st32"
795 inkscape:label="forward ALDOC_ALDOB_ALDOA_1 "
796 inkscape:connector-curvature="0"
797 id="F_ALDOC_ALDOB_ALDOA_1" /><path
798 style="fill:none;stroke:#000000;stroke-width:1.84440005"
799 d="m 988.6,115.41855 0,13.6 m -16.1,-13.5 32.6,0"
800 class="st13"
801 inkscape:connector-curvature="0"
802 id="R_ALDOC_ALDOB_ALDOA_1" /><path
803 style="fill:none;stroke:#000000;stroke-width:2.03660011"
804 d="m 990.5,127.81855 c -1.7,5.4 -1.7,5.4 -1.7,5.4 l -2.2,-5.2 2,1.3 1.9,-1.5 z m 13.7,-14.3 c 6.9,2.2 6.9,2.2 6.9,2.2 l -6.9,2.2 1.7,-2.2 -1.7,-2.2 z"
805 class="st33"
806 inkscape:label="B ALDOC_ALDOB_ALDOA_1"
807 inkscape:connector-curvature="0"
808 id="B_ALDOC_ALDOB_ALDOA_1" /><text
809 style="font-size:16px;font-family:Calibri-Bold"
810 id="text171"
811 class="st15 st16"
812 x="1014.1517"
813 y="119.70486">Ery4P</text>
814 <text
815 style="font-size:16px;font-family:Calibri-Bold"
816 id="text173"
817 class="st15 st16"
818 x="968.1048"
819 y="145.78055">DHAP</text>
820 <text
821 style="font-size:16px;font-family:Calibri-Bold"
822 id="text175"
823 class="st15 st16"
824 x="771.2854"
825 y="226.97975">PRPP</text>
826 <text
827 style="font-size:10px;font-family:Calibri"
828 id="text177"
829 class="st17 st18"
830 x="826.94464"
831 y="243.12035">Gly</text>
832 <text
833 style="font-size:10px;font-family:Calibri"
834 id="text179"
835 class="st17 st18"
836 x="913.92413"
837 y="243.37524">2 10-forTHF</text>
838 <text
839 style="font-size:10px;font-family:Calibri"
840 id="text181"
841 class="st17 st18"
842 x="857.57452"
843 y="209.29074">2 THF</text>
844 <text
845 style="font-size:10px;font-family:Calibri"
846 id="text183"
847 class="st17 st18"
848 x="884.82159"
849 y="209.54565">PPi</text>
850 <text
851 style="font-size:10px;font-family:Calibri"
852 id="text185"
853 class="st17 st18"
854 x="901.06671"
855 y="208.81564">4 ADP</text>
856 <text
857 style="font-size:10px;font-family:Calibri"
858 id="text187"
859 class="st17 st18"
860 x="836.94171"
861 y="209.48065">Fum</text>
862 <text
863 style="font-size:16px;font-family:Calibri-Bold"
864 id="text189"
865 class="st15 st16"
866 x="1001.889"
867 y="227.94115">IMP</text>
868 <text
869 style="font-size:10px;font-family:Calibri"
870 id="text191"
871 class="st17 st18"
872 x="802.77081"
873 y="243.09105">2 Gln</text>
874 <text
875 style="font-size:10px;font-family:Calibri"
876 id="text193"
877 class="st17 st18"
878 x="812.37921"
879 y="209.35135">2 Glu</text>
880 <text
881 style="font-size:10px;font-family:Calibri"
882 id="text195"
883 class="st17 st18"
884 x="890.34705"
885 y="243.16335">4 ATP</text>
886 <text
887 style="font-size:10px;font-family:Calibri"
888 id="text197"
889 class="st17 st18"
890 x="868.02661"
891 y="242.86446">H</text>
892 <text
893 style="font-size:6.09369993px;font-family:Calibri"
894 id="text199"
895 class="st17 st26"
896 x="874.25714"
897 y="244.86446">2</text>
898 <text
899 style="font-size:10px;font-family:Calibri"
900 id="text201"
901 class="st17 st18"
902 x="877.34601"
903 y="242.86446">O</text>
904 <text
905 style="font-size:10px;font-family:Calibri"
906 id="text203"
907 class="st17 st18"
908 x="964.69855"
909 y="243.09105">CO</text>
910 <text
911 style="font-size:6.09369993px;font-family:Calibri"
912 id="text205"
913 class="st17 st26"
914 x="976.56384"
915 y="245.09105">2</text>
916 <text
917 style="font-size:16px;font-family:Calibri-Bold"
918 id="text207"
919 class="st15 st16"
920 x="1268.7963"
921 y="274.35965">GDP</text>
922 <text
923 style="font-size:10px;font-family:Calibri"
924 id="text209"
925 class="st17 st18"
926 x="1227.5297"
927 y="295.81955">ATP</text>
928 <text
929 style="font-size:10px;font-family:Calibri"
930 id="text211"
931 class="st17 st18"
932 x="1245.308"
933 y="295.39575">ADP</text>
934 <text
935 style="font-size:10px;font-family:Calibri"
936 id="text213"
937 class="st17 st18"
938 x="588.70343"
939 y="538.1087">ATP</text>
940 <text
941 style="font-size:10px;font-family:Calibri"
942 id="text215"
943 class="st17 st18"
944 x="593.98761"
945 y="501.60864">ADP</text>
946 <text
947 style="font-size:10px;font-family:Calibri"
948 id="text217"
949 class="st17 st18"
950 x="617.54913"
951 y="538.3645">CoA</text>
952 <text
953 style="font-size:16px;font-family:Calibri-Bold"
954 id="text219"
955 class="st15 st16"
956 x="663.85974"
957 y="522.77277">AcCoA</text>
958 <text
959 style="font-size:10px;font-family:Calibri"
960 id="text221"
961 class="st17 st18"
962 x="631.93585"
963 y="501.30786">OAA</text>
964 <text
965 style="font-size:16px;font-family:Calibri-Bold"
966 id="text223"
967 class="st15 st16"
968 x="1047.556"
969 y="522.03638">ippPP</text>
970 <text
971 style="font-size:16px;font-family:Calibri-Bold"
972 id="text225"
973 class="st15 st16"
974 x="1123.9662"
975 y="522.45044">fPP</text>
976 <text
977 style="font-size:16px;font-family:Calibri-Bold"
978 id="text227"
979 class="st15 st16"
980 x="1293.7357"
981 y="521.42017">Chol</text>
982 <text
983 style="font-size:10px;font-family:Calibri"
984 id="text229"
985 class="st17 st18"
986 x="715.52472"
987 y="482.08426">ATP</text>
988 <text
989 style="font-size:10px;font-family:Calibri"
990 id="text231"
991 class="st17 st18"
992 x="735.80505"
993 y="481.85086">HCO</text>
994 <text
995 style="font-size:6.09369993px;font-family:Calibri"
996 id="text233"
997 class="st17 st26"
998 x="753.9007"
999 y="483.85086">3</text>
1000 <text
1001 style="font-size:6.09369993px;font-family:Calibri"
1002 id="text235"
1003 class="st17 st26"
1004 x="756.98865"
1005 y="476.35086">-</text>
1006 <text
1007 style="font-size:10px;font-family:Calibri"
1008 id="text237"
1009 class="st17 st18"
1010 x="763.59314"
1011 y="481.23465">H</text>
1012 <text
1013 style="font-size:10px;font-family:Calibri"
1014 id="text239"
1015 class="st17 st18"
1016 x="727.01691"
1017 y="449.72195">ADP</text>
1018 <text
1019 style="font-size:10px;font-family:Calibri"
1020 id="text241"
1021 class="st17 st18"
1022 x="766.38605"
1023 y="449.12424">Pi</text>
1024 <text
1025 style="font-size:16px;font-family:Calibri-Bold"
1026 id="text243"
1027 class="st15 st16"
1028 x="790.05304"
1029 y="468.83524">MalCoA</text>
1030 <text
1031 style="font-size:10px;font-family:Calibri"
1032 id="text245"
1033 class="st17 st18"
1034 x="882.31775"
1035 y="413.45636">CO</text>
1036 <text
1037 style="font-size:6.09369993px;font-family:Calibri"
1038 id="text247"
1039 class="st17 st26"
1040 x="894.18292"
1041 y="415.45636">2</text>
1042 <text
1043 style="font-size:16px;font-family:Calibri-Bold"
1044 id="text249"
1045 class="st15 st16"
1046 x="914.74835"
1047 y="432.96216">AcAcACP</text>
1048 <text
1049 style="font-size:10px;font-family:Calibri"
1050 id="text251"
1051 class="st17 st18"
1052 x="999.9397"
1053 y="447.29025">14NADPH</text>
1054 <text
1055 style="font-size:10px;font-family:Calibri"
1056 id="text253"
1057 class="st17 st18"
1058 x="1008.5541"
1059 y="412.44064">14NADP</text>
1060 <text
1061 style="font-size:10px;font-family:Calibri"
1062 id="text255"
1063 class="st17 st18"
1064 x="1071.347"
1065 y="412.67795">6 H</text>
1066 <text
1067 style="font-size:6.09369993px;font-family:Calibri"
1068 id="text257"
1069 class="st17 st26"
1070 x="1084.9066"
1071 y="414.67795">2</text>
1072 <text
1073 style="font-size:10px;font-family:Calibri"
1074 id="text259"
1075 class="st17 st18"
1076 x="1087.9945"
1077 y="412.67795">O</text>
1078 <text
1079 style="font-size:10px;font-family:Calibri"
1080 id="text261"
1081 class="st17 st18"
1082 x="1045.3734"
1083 y="412.36255">6 CO</text>
1084 <text
1085 style="font-size:6.09369993px;font-family:Calibri"
1086 id="text263"
1087 class="st17 st26"
1088 x="1064.5677"
1089 y="414.36255">2</text>
1090 <text
1091 style="font-size:16px;font-family:Calibri-Bold"
1092 id="text265"
1093 class="st15 st16"
1094 x="1105.4926"
1095 y="433.46994">Palm</text>
1096 <text
1097 style="font-size:10px;font-family:Calibri"
1098 id="text267"
1099 class="st17 st18"
1100 x="949.78149"
1101 y="447.81464">6 MalACP</text>
1102 <text
1103 style="font-size:10px;font-family:Calibri"
1104 id="text269"
1105 class="st17 st18"
1106 x="982.41632"
1107 y="413.04025">7 ACP</text>
1108 <text
1109 style="font-size:10px;font-family:Calibri"
1110 id="text271"
1111 class="st17 st18"
1112 x="857.53351"
1113 y="449.55005">CoA</text>
1114 <text
1115 style="font-size:16px;font-family:Calibri-Bold"
1116 id="text273"
1117 class="st15 st16"
1118 x="887.2757"
1119 y="468.92606">MalACP</text>
1120 <text
1121 style="font-size:10px;font-family:Calibri"
1122 id="text275"
1123 class="st17 st18"
1124 x="848.5813"
1125 y="482.83524">ACP</text>
1126 <text
1127 style="font-size:10px;font-family:Calibri"
1128 id="text277"
1129 class="st17 st18"
1130 x="756.85382"
1131 y="411.64575">CoA</text>
1132 <text
1133 style="font-size:16px;font-family:Calibri-Bold"
1134 id="text279"
1135 class="st15 st16"
1136 x="791.37335"
1137 y="434.89474">AcACP</text>
1138 <text
1139 style="font-size:10px;font-family:Calibri"
1140 id="text281"
1141 class="st17 st18"
1142 x="747.01202"
1143 y="447.85574">ACP</text>
1144 <path
1145 style="fill:none;stroke:#000000;stroke-width:1.59029996"
1146 d="m 761,430.21855 c -5.4,1.2 -4.9,10.4 -4.9,10.4 m 4.5,-10.5 c 5.3,-1 4,-9.8 4,-9.8 m -64.6,89 0.4,-79.2 79.6,0"
1147 class="st34"
1148 inkscape:connector-curvature="0"
1149 id="R_FASN_1" /><path
1150 style="fill:none;stroke:#000000;stroke-width:1.72870004"
1151 d="m 855.7,430.31855 c 6.2,-0.4 7.2,-8.3 7.2,-8.3 m 28,33.5 -10,-25.7 m -45.2,0.4 68.9,-0.3 m -20.5,0.2 c 6.1,-0.6 6.4,-8.5 6.4,-8.5"
1152 class="st35"
1153 inkscape:connector-curvature="0"
1154 id="R_AcAcACPSynthesis" /><text
1155 style="font-size:10px;font-family:Calibri"
1156 id="text285"
1157 class="st17 st18"
1158 x="855.91821"
1159 y="414.73166">ACP</text>
1160 <path
1161 style="fill:none;stroke:#000000;stroke-width:1.77409995"
1162 d="m 729.6,464.51855 c -6,1.1 -5.5,9.1 -5.5,9.1 m 5.8,-9.3 c 5.9,-0.9 4.4,-8.8 4.4,-8.8 m 30.6,8.8 c 5.9,-0.9 4.4,-8.8 4.4,-8.8 m -59.2,8.5 25.7,0.6 44.2,-0.3 m -28,0.2 c -6,1.1 -5.5,9.1 -5.5,9.1 m 25.5,-9.1 c -6,1.1 -5.5,9.1 -5.5,9.1 m -56.2,37.3 0,-47.7"
1163 class="st36"
1164 inkscape:label="ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2"
1165 inkscape:connector-curvature="0"
1166 id="R_ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2" /><path
1167 style="fill:none;stroke:#000000;stroke-width:2.23090005"
1168 d="m 1428,1116.5186 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z m 57.5,-14.1 c 1.8,-5.9 1.8,-5.9 1.8,-5.9 l 2.5,5.6 -2.3,-1.3 -2,1.6 z"
1169 class="st37"
1170 inkscape:connector-curvature="0"
1171 id="F_ALDH3B1_ALDH3A1_ALDH3B2_ALDH1A3" /><path
1172 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1173 d="m 1499.2,1027.2186 -73.8,0 0,0 m 21.8,0 c -5.9,-1.6 -4.4,-14.8 -4.4,-14.8 m 43.4,14.6 c 4.7,-3.6 3.8,-14.7 1.1,-14.6"
1174 class="st32"
1175 inkscape:connector-curvature="0"
1176 id="R_SLC25A3" /><text
1177 style="font-size:16px;font-family:Calibri-Bold"
1178 id="text290"
1179 class="st15 st16"
1180 x="1480.8578"
1181 y="1008.175">H</text>
1182 <text
1183 style="font-size:16px;font-family:Calibri-Bold"
1184 id="text292"
1185 class="st15 st16"
1186 x="1501.9437"
1187 y="1029.9797">Pi</text>
1188 <text
1189 style="font-size:16px;font-family:Calibri-Bold"
1190 id="text294"
1191 class="st15 st16"
1192 x="1438.8285"
1193 y="1005.4563">H</text>
1194 <text
1195 style="font-size:16px;font-family:Calibri-Bold"
1196 id="text296"
1197 class="st15 st16"
1198 x="1401.4027"
1199 y="1030.7034">Pi</text>
1200 <path
1201 style="fill:none;stroke:#000000;stroke-width:2.23090005"
1202 d="m 1425.9,1028.9186 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z m 14.4,-15.2 c 2.4,-5.7 2.4,-5.7 2.4,-5.7 l 2,5.8 -2.1,-1.5 -2.3,1.4 z"
1203 class="st37"
1204 inkscape:connector-curvature="0"
1205 id="F_SLC25A3" /><path
1206 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1207 d="m 1502.9,1072.8186 c -24.6,0 -49.2,0 -73.8,0 m 21.8,0 c -3.5,-1 -4.2,-5.1 -4.5,-8.3 -0.2,-2 -0.1,-3.9 0.1,-5.9 m 43,14 c 0.4,-4.6 2.5,-9 2.7,-13.7 0,-0.4 -0.1,-1.1 -0.7,-1.1"
1208 class="st32"
1209 inkscape:connector-curvature="0"
1210 id="R_SLC25A5_SLC25A4_SLC25A6" /><text
1211 style="font-size:16px;font-family:Calibri-Bold"
1212 id="text300"
1213 class="st15 st16"
1214 x="1479.5199"
1215 y="1049.1731">ATP</text>
1216 <text
1217 style="font-size:16px;font-family:Calibri-Bold"
1218 id="text302"
1219 class="st15 st16"
1220 x="1511.3929"
1221 y="1077.179">ADP</text>
1222 <text
1223 style="font-size:16px;font-family:Calibri-Bold"
1224 id="text304"
1225 class="st15 st16"
1226 x="1432.8539"
1227 y="1049.8508">ATP</text>
1228 <text
1229 style="font-size:16px;font-family:Calibri-Bold"
1230 id="text306"
1231 class="st15 st16"
1232 x="1391.6039"
1233 y="1077.1125">ADP</text>
1234 <path
1235 style="fill:none;stroke:#000000;stroke-width:2.23090005"
1236 d="m 1429.5,1074.5186 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z m 61,-14.2 c 2.1,-5.8 2.1,-5.8 2.1,-5.8 l 2.2,5.7 -2.2,-1.4 -2.1,1.5 z"
1237 class="st37"
1238 inkscape:label="#F_SLC25A5_SLC25A4_SLC25A6"
1239 inkscape:connector-curvature="0"
1240 id="F_SLC25A5_SLC25A4_SLC25A6" /><path
1241 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1242 d="m 1501.4,1114.8186 -73.8,0 0,0 m 21.8,0 c -5.9,-1.4 -4.4,-13.5 -4.4,-13.5 m 41.7,-1 c 3.2,6.1 -5.5,14.6 -5.5,14.6"
1243 class="st32"
1244 inkscape:connector-curvature="0"
1245 id="R_ALDH3B1_ALDH3A1_ALDH3B2_ALDH1A3" /><text
1246 style="font-size:14px;font-family:Calibri-Bold"
1247 id="text310"
1248 class="st15 st38"
1249 x="1473.5541"
1250 y="1092.8215">GTP</text>
1251 <text
1252 style="font-size:16px;font-family:Calibri-Bold"
1253 id="text312"
1254 class="st15 st16"
1255 x="1509.8929"
1256 y="1117.5793">GDP</text>
1257 <text
1258 style="font-size:14px;font-family:Calibri-Bold"
1259 id="text314"
1260 class="st15 st38"
1261 x="1428.8754"
1262 y="1092.8958">GTP</text>
1263 <text
1264 style="font-size:16px;font-family:Calibri-Bold"
1265 id="text316"
1266 class="st15 st16"
1267 x="1390.0355"
1268 y="1119.3235">GDP</text>
1269 <path
1270 style="fill:none;stroke:#000000;stroke-width:2.23090005"
1271 d="m 1500.2,1112.5186 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z m -57.8,-10.4 c 2.4,-5.7 2.4,-5.7 2.4,-5.7 l 2,5.8 -2.1,-1.5 -2.3,1.4 z"
1272 class="st37"
1273 inkscape:connector-curvature="0"
1274 id="B_ALDH3B1_ALDH3A1_ALDH3B2_ALDH1A3" /><path
1275 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1276 d="m 1442.3,832.21855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
1277 class="st32"
1278 inkscape:label="forward AQP8 "
1279 inkscape:connector-curvature="0"
1280 id="F_AQP8" /><path
1281 style="fill:none;stroke:#000000;stroke-width:1.77520001"
1282 d="m 1493,830.41855 -50.4,0 0,0"
1283 class="st39"
1284 inkscape:label="AQP8 "
1285 inkscape:connector-curvature="0"
1286 id="R_AQP8" /><path
1287 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1288 d="m 1489,828.11855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
1289 class="st32"
1290 inkscape:transform-center-y="2.6134784"
1291 inkscape:transform-center-x="-0.38596577"
1292 inkscape:label="backward AQP8 "
1293 inkscape:connector-curvature="0"
1294 id="B_AQP8" /><text
1295 style="font-size:16px;font-family:Calibri-Bold"
1296 id="text322"
1297 class="st15 st16"
1298 x="1501.9828"
1299 y="834.84888">H</text>
1300 <text
1301 style="font-size:9.75px;font-family:Calibri-Bold"
1302 id="text324"
1303 class="st15 st40"
1304 x="1512.0765"
1305 y="838.04907">2</text>
1306 <text
1307 style="font-size:16px;font-family:Calibri-Bold"
1308 id="text326"
1309 class="st15 st16"
1310 x="1517.0179"
1311 y="834.84888">O</text>
1312 <text
1313 style="font-size:16px;font-family:Calibri-Bold"
1314 id="text328"
1315 class="st15 st16"
1316 x="1405.2406"
1317 y="834.85181">H</text>
1318 <text
1319 style="font-size:9.75px;font-family:Calibri-Bold"
1320 id="text330"
1321 class="st15 st40"
1322 x="1415.3344"
1323 y="838.052">2</text>
1324 <text
1325 style="font-size:16px;font-family:Calibri-Bold"
1326 id="text332"
1327 class="st15 st16"
1328 x="1420.2758"
1329 y="834.85181">O</text>
1330 <text
1331 style="font-size:16px;font-family:Calibri-Bold"
1332 id="text334"
1333 class="st15 st16"
1334 x="1501.2924"
1335 y="920.34888">O</text>
1336 <text
1337 style="font-size:9.75px;font-family:Calibri-Bold"
1338 id="text336"
1339 class="st15 st40"
1340 x="1512.1127"
1341 y="923.54907">2</text>
1342 <text
1343 style="font-size:16px;font-family:Calibri-Bold"
1344 id="text338"
1345 class="st15 st16"
1346 x="1414.5111"
1347 y="921.31366">O</text>
1348 <text
1349 style="font-size:9.75px;font-family:Calibri-Bold"
1350 id="text340"
1351 class="st15 st40"
1352 x="1425.3314"
1353 y="924.51385">2</text>
1354 <text
1355 style="font-size:16px;font-family:Calibri-Bold"
1356 id="text342"
1357 class="st15 st16"
1358 x="1500.6859"
1359 y="857.42798">CO</text>
1360 <text
1361 style="font-size:9.75px;font-family:Calibri-Bold"
1362 id="text344"
1363 class="st15 st40"
1364 x="1519.8578"
1365 y="860.6272">2</text>
1366 <text
1367 style="font-size:16px;font-family:Calibri-Bold"
1368 id="text346"
1369 class="st15 st16"
1370 x="1405.0785"
1371 y="858.29315">CO</text>
1372 <text
1373 style="font-size:9.75px;font-family:Calibri-Bold"
1374 id="text348"
1375 class="st15 st40"
1376 x="1424.2504"
1377 y="861.49341">2</text>
1378 <text
1379 style="font-size:16px;font-family:Calibri-Bold"
1380 id="text350"
1381 class="st15 st16"
1382 x="1500.932"
1383 y="879.84888">CoA</text>
1384 <text
1385 style="font-size:16px;font-family:Calibri-Bold"
1386 id="text352"
1387 class="st15 st16"
1388 x="1400.6957"
1389 y="879.69458">CoA</text>
1390 <path
1391 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1392 d="m 1441.9,917.71855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
1393 class="st32"
1394 inkscape:label="TransportOxygen F"
1395 inkscape:connector-curvature="0"
1396 id="F_TransportOxygen" /><path
1397 style="fill:none;stroke:#000000;stroke-width:1.88160002"
1398 d="m 1497.8,915.91855 -56.7,0 0,0"
1399 class="st41"
1400 inkscape:label="TransportOxygen"
1401 inkscape:connector-curvature="0"
1402 id="R_TransportOxygen" /><path
1403 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1404 d="m 1440.8,854.71855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
1405 class="st32"
1406 inkscape:label="forward Transport_CO2 "
1407 inkscape:connector-curvature="0"
1408 id="F_Transport_CO2" /><path
1409 style="fill:none;stroke:#000000;stroke-width:1.86150002"
1410 d="m 1493.5,852.91855 -55.5,0 0,0"
1411 class="st42"
1412 inkscape:label="Transport_CO2 "
1413 inkscape:connector-curvature="0"
1414 id="R_Transport_CO2" /><path
1415 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1416 d="m 1489,850.31855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
1417 class="st32"
1418 inkscape:transform-center-y="2.6134784"
1419 inkscape:transform-center-x="-0.38596577"
1420 inkscape:label="backward Transport_CO2 "
1421 inkscape:connector-curvature="0"
1422 id="B_Transport_CO2" /><path
1423 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1424 d="m 1440.8,877.21855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
1425 class="st32"
1426 inkscape:label="backward SLC25A16 "
1427 inkscape:connector-curvature="0"
1428 id="B_SLC25A16" /><path
1429 style="fill:none;stroke:#000000;stroke-width:1.79229999"
1430 d="m 1492.5,875.11855 -51.4,0 0,0"
1431 class="st43"
1432 inkscape:label="SLC25A16 "
1433 inkscape:connector-curvature="0"
1434 id="R_SLC25A16" /><path
1435 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1436 d="m 1490.5,872.71855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
1437 class="st32"
1438 inkscape:transform-center-y="2.6134784"
1439 inkscape:transform-center-x="-0.38596577"
1440 inkscape:label="forward SLC25A16 "
1441 inkscape:connector-curvature="0"
1442 id="F_SLC25A16" /><text
1443 style="font-size:16px;font-family:Calibri-Bold"
1444 id="text362"
1445 class="st15 st16"
1446 x="1501.2006"
1447 y="899.49829">NH</text>
1448 <text
1449 style="font-size:9.75px;font-family:Calibri-Bold"
1450 id="text364"
1451 class="st15 st40"
1452 x="1521.8334"
1453 y="902.69849">3</text>
1454 <text
1455 style="font-size:16px;font-family:Calibri-Bold"
1456 id="text366"
1457 class="st15 st16"
1458 x="1402.0922"
1459 y="899.6507">NH</text>
1460 <text
1461 style="font-size:9.75px;font-family:Calibri-Bold"
1462 id="text368"
1463 class="st15 st40"
1464 x="1422.725"
1465 y="902.85089">3</text>
1466 <path
1467 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1468 d="m 1439.3,896.71855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
1469 class="st32"
1470 inkscape:label="forward HIBCH "
1471 inkscape:connector-curvature="0"
1472 id="F_HIBCH" /><path
1473 style="fill:none;stroke:#000000;stroke-width:1.86909997"
1474 d="m 1494.1,894.91855 -55.9,0 0,0"
1475 class="st44"
1476 inkscape:label="HIBCH "
1477 inkscape:connector-curvature="0"
1478 id="R_HIBCH" /><path
1479 style="fill:none;stroke:#000000;stroke-width:2.44919991"
1480 d="m 1490.8,892.61855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
1481 class="st32"
1482 inkscape:transform-center-y="2.6134784"
1483 inkscape:transform-center-x="-0.38596577"
1484 inkscape:label="backward HIBCH "
1485 inkscape:connector-curvature="0"
1486 id="B_HIBCH" /><text
1487 style="font-size:16px;font-family:Calibri-Bold"
1488 id="text373"
1489 class="st15 st16"
1490 x="183.5808"
1491 y="877.27655">AKG</text>
1492 <text
1493 style="font-size:16px;font-family:Calibri-Bold"
1494 id="text375"
1495 class="st15 st16"
1496 x="284.44901"
1497 y="878.07635">AKG</text>
1498 <path
1499 style="fill:none;stroke:#000000;stroke-width:2.82299995"
1500 d="m 275.8,872.81855 -60.2,-0.3 m 44.6,0.3 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -26.7,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7"
1501 class="st45"
1502 inkscape:connector-curvature="0"
1503 id="R_SLC25A10_3" /><text
1504 style="font-size:14px;font-family:Calibri-Bold"
1505 id="text378"
1506 class="st15 st38"
1507 x="225.0891"
1508 y="851.62427">Pi</text>
1509 <path
1510 style="fill:none;stroke:#000000;stroke-width:2.35560012"
1511 d="m 233.9,861.71855 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 40.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
1512 class="st46"
1513 inkscape:connector-curvature="0"
1514 id="F_SLC25A10_3" /><text
1515 style="font-size:16px;font-family:Calibri-Bold"
1516 id="text381"
1517 class="st15 st16"
1518 x="541.16345"
1519 y="867.11346">OAA</text>
1520 <text
1521 style="font-size:16px;font-family:Calibri-Bold"
1522 id="text383"
1523 class="st15 st16"
1524 x="444.4646"
1525 y="817.42017">AcCoA</text>
1526 <text
1527 style="font-size:16px;font-family:Calibri-Bold"
1528 id="text385"
1529 class="st15 st16"
1530 x="552.0061"
1531 y="801.70825">Cit</text>
1532 <text
1533 style="font-size:16px;font-family:Calibri-Bold"
1534 id="text387"
1535 class="st15 st16"
1536 x="584.02271"
1537 y="750.14575">Isocit</text>
1538 <text
1539 style="font-size:16px;font-family:Calibri-Bold"
1540 id="text389"
1541 class="st15 st16"
1542 x="720.78931"
1543 y="750.92017">AKG</text>
1544 <text
1545 style="font-size:10px;font-family:Calibri"
1546 id="text391"
1547 class="st17 st18"
1548 x="618.72882"
1549 y="720.4563">NADP</text>
1550 <text
1551 style="font-size:10px;font-family:Calibri"
1552 id="text393"
1553 class="st17 st18"
1554 x="647.54321"
1555 y="718.54126">NADPH</text>
1556 <text
1557 style="font-size:10px;font-family:Calibri"
1558 id="text395"
1559 class="st17 st18"
1560 x="620.67413"
1561 y="781.10181">NAD</text>
1562 <text
1563 style="font-size:10px;font-family:Calibri"
1564 id="text397"
1565 class="st17 st18"
1566 x="649.48175"
1567 y="783.26978">NADH</text>
1568 <text
1569 style="font-size:16px;font-family:Calibri-Bold"
1570 id="text399"
1571 class="st15 st16"
1572 x="762.93884"
1573 y="808.12225">SuCoA</text>
1574 <text
1575 style="font-size:16px;font-family:Calibri-Bold"
1576 id="text401"
1577 class="st15 st16"
1578 x="768.40649"
1579 y="883.388">Succ</text>
1580 <text
1581 style="font-size:16px;font-family:Calibri-Bold"
1582 id="text403"
1583 class="st15 st16"
1584 x="702.18781"
1585 y="941.1272">Fum</text>
1586 <text
1587 style="font-size:16px;font-family:Calibri-Bold"
1588 id="text405"
1589 class="st15 st16"
1590 x="578.7005"
1591 y="921.75116">Mal</text>
1592 <path
1593 style="fill:none;stroke:#000000;stroke-width:2.04839993"
1594 d="m 566.7,779.01855 c -1.3,6.1 -1.3,6.1 -1.3,6.1 l 4.5,-4.4 -2.3,0.5 -0.9,-2.2 z"
1595 class="st47"
1596 inkscape:label="backward aconitase"
1597 inkscape:connector-curvature="0"
1598 id="B_ACO2_ACO1_1" /><path
1599 style="fill:none;stroke:#000000;stroke-width:1.12699997"
1600 d="m 566.9,782.01855 c 4.6,-9.3 11.1,-17.4 19,-23.8"
1601 class="st48"
1602 inkscape:connector-curvature="0"
1603 id="R_ACO2_ACO1_1" /><path
1604 style="fill:none;stroke:#000000;stroke-width:2.04839993"
1605 d="m 585.4,760.31855 c 3.7,-5 3.7,-5 3.7,-5 l -5.8,2.2 2.3,0.5 -0.2,2.3 z"
1606 class="st47"
1607 inkscape:label="forward aconitase"
1608 inkscape:connector-curvature="0"
1609 id="F_ACO2_ACO1_1" /><path
1610 style="fill:none;stroke:#000000;stroke-width:2.04839993"
1611 d="m 613.2,930.01855 c -5.9,-2.2 -5.9,-2.2 -5.9,-2.2 l 3.7,5 -0.1,-2.3 2.3,-0.5 z"
1612 class="st47"
1613 inkscape:label="forward fumarase"
1614 inkscape:connector-curvature="0"
1615 id="F_FH_1" /><path
1616 style="fill:none;stroke:#000000;stroke-width:1.53830004"
1617 d="m 750,753.21855 c 11.4,9.5 20.7,21.6 27.4,35.6 m 7.1,-13.7 c -5.5,3.4 -13.1,1.9 -17.3,-3.3 -4.2,-5.2 -3.5,-12.4 1.5,-16.3"
1618 class="st49"
1619 inkscape:label="DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL"
1620 inkscape:connector-curvature="0"
1621 id="R_DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL" /><text
1622 style="font-size:10px;font-family:Calibri"
1623 id="text412"
1624 class="st17 st18"
1625 x="770.49744"
1626 y="758.63306">NAD</text>
1627 <text
1628 style="font-size:10px;font-family:Calibri"
1629 id="text414"
1630 class="st17 st18"
1631 x="788.89093"
1632 y="758.63306">+</text>
1633 <text
1634 style="font-size:10px;font-family:Calibri"
1635 id="text416"
1636 class="st17 st18"
1637 x="793.8714"
1638 y="758.63306">CoA</text>
1639 <path
1640 style="fill:none;stroke:#000000;stroke-width:1.4921"
1641 d="m 804.5,854.61855 c -5.7,0.4 -11.1,-2.1 -14.1,-6.4 -3,-4.3 -3,-9.8 -0.1,-14.1 2.9,-4.3 8.3,-6.9 14,-6.5 m -18.4,38.9 c 3.7,-17.5 3.4,-35.7 -0.7,-53.3"
1642 class="st50"
1643 inkscape:connector-curvature="0"
1644 id="R_KANK1_SUCLA2_SUCLG1_SUCLG2_1" /><text
1645 style="font-size:10px;font-family:Calibri"
1646 id="text419"
1647 class="st17 st18"
1648 x="812.39685"
1649 y="828.55005">GDP</text>
1650 <text
1651 style="font-size:10px;font-family:Calibri"
1652 id="text421"
1653 class="st17 st18"
1654 x="830.02374"
1655 y="828.55005">+</text>
1656 <text
1657 style="font-size:10px;font-family:Calibri"
1658 id="text423"
1659 class="st17 st18"
1660 x="835.00421"
1661 y="828.55005">Pi</text>
1662 <text
1663 style="font-size:10px;font-family:Calibri"
1664 id="text425"
1665 class="st17 st18"
1666 x="814.06671"
1667 y="857.71606">GTP</text>
1668 <text
1669 style="font-size:10px;font-family:Calibri"
1670 id="text427"
1671 class="st17 st18"
1672 x="830.36554"
1673 y="857.71606">+</text>
1674 <text
1675 style="font-size:10px;font-family:Calibri"
1676 id="text429"
1677 class="st17 st18"
1678 x="835.34601"
1679 y="857.71606">CoA</text>
1680 <path
1681 style="fill:none;stroke:#000000;stroke-width:1.41170001"
1682 d="m 762.8,933.01855 c -4.7,-2.1 -7.7,-6.5 -7.5,-11.2 0.2,-4.7 3.4,-8.9 8.2,-10.5 4.8,-1.7 10.3,-0.5 14,2.9 m -2.6,-22 c -9,15.5 -21.4,28.8 -36.4,39.2"
1683 class="st51"
1684 inkscape:connector-curvature="0"
1685 id="R_SDHA_SDHB_SDHC_SDHD" /><text
1686 style="font-size:10px;font-family:Calibri"
1687 id="text432"
1688 class="st17 st18"
1689 x="784.63501"
1690 y="920.19165">FAD</text>
1691 <text
1692 style="font-size:10px;font-family:Calibri"
1693 id="text434"
1694 class="st17 st18"
1695 x="764.34894"
1696 y="943.30975">FADH</text>
1697 <text
1698 style="font-size:6.09369993px;font-family:Calibri"
1699 id="text436"
1700 class="st17 st26"
1701 x="786.55115"
1702 y="945.30975">2</text>
1703 <path
1704 style="fill:none;stroke:#000000;stroke-width:1.37870002"
1705 d="m 578.6,907.21855 c -8.4,-8.4 -15,-18.8 -19.3,-30.4 m -8,12 c 3.1,-2 7.4,-2.3 10.9,-0.8 3.6,1.6 5.8,4.7 5.8,8.2 0,3.4 -2.2,6.6 -5.8,8"
1706 class="st52"
1707 inkscape:connector-curvature="0"
1708 id="R_MDH2" /><text
1709 style="font-size:10px;font-family:Calibri"
1710 id="text439"
1711 class="st17 st18"
1712 x="537.08234"
1713 y="912.11646">NAD</text>
1714 <text
1715 style="font-size:16px;font-family:Calibri-Bold"
1716 id="text441"
1717 class="st15 st16"
1718 x="451.4158"
1719 y="732.70825">Pyr</text>
1720 <path
1721 style="fill:none;stroke:#000000;stroke-width:2.24370003"
1722 d="m 464.2,739.41855 0.2,56.6 m -0.5,-21.6 c 1.5,5.9 13.6,4.1 13.6,4.1 m -13.3,-14.1 c 1.5,5.9 13.4,4.1 13.4,4.1 m -13.1,1.8 c -1.6,-6 -12.9,-5.2 -12.9,-5.2 m 12.4,-12.6 c -1.5,-6 -12.4,-5.2 -12.4,-5.2 m 12.7,6.1 c 1.5,5.9 13.2,4.1 13.2,4.1"
1723 class="st53"
1724 inkscape:label="DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB "
1725 inkscape:connector-curvature="0"
1726 id="R_DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB" /><text
1727 style="font-size:10px;font-family:Calibri"
1728 id="text444"
1729 class="st17 st18"
1730 x="567.64972"
1731 y="846.81366">H</text>
1732 <text
1733 style="font-size:6.09369993px;font-family:Calibri"
1734 id="text446"
1735 class="st17 st26"
1736 x="573.88025"
1737 y="848.81366">2</text>
1738 <text
1739 style="font-size:10px;font-family:Calibri"
1740 id="text448"
1741 class="st17 st18"
1742 x="576.96814"
1743 y="846.81366">O</text>
1744 <text
1745 style="font-size:10px;font-family:Calibri"
1746 id="text450"
1747 class="st17 st18"
1748 x="569.51593"
1749 y="825.74438">CoA</text>
1750 <text
1751 style="font-size:10px;font-family:Calibri"
1752 id="text452"
1753 class="st17 st18"
1754 x="695.72681"
1755 y="780.76196">CO</text>
1756 <text
1757 style="font-size:6.09369993px;font-family:Calibri"
1758 id="text454"
1759 class="st17 st26"
1760 x="707.5921"
1761 y="782.76196">2</text>
1762 <text
1763 style="font-size:10px;font-family:Calibri"
1764 id="text456"
1765 class="st17 st18"
1766 x="696.48865"
1767 y="719.4046">CO</text>
1768 <text
1769 style="font-size:6.09369993px;font-family:Calibri"
1770 id="text458"
1771 class="st17 st26"
1772 x="708.35382"
1773 y="721.4046">2</text>
1774 <path
1775 style="fill:none;stroke:#000000;stroke-width:2.04839993"
1776 d="m 664.2,952.91855 c 5.8,2.2 5.8,2.2 5.8,2.2 l -3.7,-5 0.1,2.3 -2.2,0.5 z m 27.9,-11.2 c 4.9,-3.8 4.9,-3.8 4.9,-3.8 l -6.2,0.6 2,1.1 -0.7,2.1 z"
1777 class="st47"
1778 inkscape:connector-curvature="0"
1779 id="B_FH_1" /><path
1780 style="fill:none;stroke:#000000;stroke-width:1.84920001"
1781 d="m 666.6,952.31855 -16.4,-9.8 m 41.7,-2.8 c -33.5,7.3 -52.1,2.6 -79.1,-8.8"
1782 class="st54"
1783 inkscape:connector-curvature="0"
1784 id="R_FH_1" /><text
1785 style="font-size:10px;font-family:Calibri"
1786 id="text462"
1787 class="st17 st18"
1788 x="672.46021"
1789 y="961.96796">H</text>
1790 <text
1791 style="font-size:6.09369993px;font-family:Calibri"
1792 id="text464"
1793 class="st17 st26"
1794 x="678.69073"
1795 y="963.96796">2</text>
1796 <text
1797 style="font-size:10px;font-family:Calibri"
1798 id="text466"
1799 class="st17 st18"
1800 x="681.7796"
1801 y="961.96796">O</text>
1802 <path
1803 style="fill:none;stroke:#000000;stroke-width:1.81599998"
1804 d="m 561.8,902.51855 c -4,4 -4,4 -4,4 l 5.5,-0.9 -1.9,-1 0.4,-2.1 z m 13.6,3.9 c 6,1.7 6,1.7 6,1.7 l -4.1,-4.7 0.3,2.3 -2.2,0.7 z"
1805 class="st55"
1806 inkscape:connector-curvature="0"
1807 id="B_MDH2" /><path
1808 style="fill:none;stroke:#000000;stroke-width:1.81599998"
1809 d="m 739.7,928.21855 c -4.1,4.7 -4.1,4.7 -4.1,4.7 l 6,-1.7 -2.2,-0.7 0.3,-2.3 z m 21.4,5.7 c 5.3,1.4 5.3,1.4 5.3,1.4 l -3.6,-4.5 0.3,2.3 -2,0.8 z"
1810 class="st55"
1811 inkscape:connector-curvature="0"
1812 id="F_SDHA_SDHB_SDHC_SDHD" /><path
1813 style="fill:none;stroke:#000000;stroke-width:1.81599998"
1814 d="m 774.9,896.21855 c 1.3,-6.1 1.3,-6.1 1.3,-6.1 l -4.4,4.4 2.3,-0.5 0.8,2.2 z m 1.2,19.4 c 6.1,1.1 6.1,1.1 6.1,1.1 l -4.5,-4.3 0.5,2.2 -2.1,1 z"
1815 class="st55"
1816 inkscape:connector-curvature="0"
1817 id="B_SDHA_SDHB_SDHC_SDHD" /><path
1818 style="fill:none;stroke:#000000;stroke-width:1.81599998"
1819 d="m 785.2,863.01855 c 0.1,6.2 0.1,6.2 0.1,6.2 l 3.3,-5.3 -2.1,1 -1.3,-1.9 z m 18.8,-7 c 6.1,-1.5 6.1,-1.5 6.1,-1.5 l -5.9,-2 1.4,1.8 -1.6,1.7 z"
1820 class="st55"
1821 inkscape:connector-curvature="0"
1822 id="F_KANK1_SUCLA2_SUCLG1_SUCLG2_1" /><path
1823 style="fill:none;stroke:#000000;stroke-width:1.81599998"
1824 d="m 788.1,817.61855 c -3.6,-5.1 -3.6,-5.1 -3.6,-5.1 l 0.2,6.2 1.2,-2 2.2,0.9 z m 14.8,11.6 c 6,-1.6 6,-1.6 6,-1.6 l -5.9,-1.9 1.5,1.8 -1.6,1.7 z"
1825 class="st55"
1826 inkscape:connector-curvature="0"
1827 id="B_KANK1_SUCLA2_SUCLG1_SUCLG2_1" /><text
1828 style="font-size:16px;font-family:Calibri-Bold"
1829 id="text473"
1830 class="st15 st16"
1831 x="177.26639"
1832 y="802.27655">Fum</text>
1833 <text
1834 style="font-size:16px;font-family:Calibri-Bold"
1835 id="text475"
1836 class="st15 st16"
1837 x="283.87378"
1838 y="800.91235">Fum</text>
1839 <path
1840 style="fill:none;stroke:#000000;stroke-width:2.82299995"
1841 d="m 275.8,797.81855 -60.2,-0.3 m 44.6,0.2 c 5.9,-1.6 4.4,-15.3 4.4,-15.3 m -31.3,15.6 c -6.4,-4.5 -7.8,-15.5 -5,-15.5"
1842 class="st45"
1843 inkscape:connector-curvature="0"
1844 id="R_SLC25A10_4" /><path
1845 style="fill:none;stroke:#000000;stroke-width:2.0158999"
1846 d="m 229.9,783.11855 c -2.1,-4.9 -2.1,-4.9 -2.1,-4.9 l -2,5 2.1,-1.3 2,1.2 z m 44.1,16.7 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
1847 class="st56"
1848 inkscape:label=" B SLC25A10_4"
1849 inkscape:connector-curvature="0"
1850 id="B_SLC25A10_4" /><path
1851 style="fill:none;stroke:#000000;stroke-width:2.00889993"
1852 d="m 267,783.11855 c -1.6,-5.3 -1.6,-5.3 -1.6,-5.3 l -2.3,5.1 2,-1.2 1.9,1.4 z m -50.7,12.4 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
1853 class="st57"
1854 inkscape:label="F SLC25A10_4"
1855 inkscape:connector-curvature="0"
1856 id="F_SLC25A10_4" /><text
1857 style="font-size:14px;font-family:Calibri-Bold"
1858 id="text480"
1859 class="st15 st38"
1860 x="260.33328"
1861 y="777.0979">Pi</text>
1862 <text
1863 style="font-size:14px;font-family:Calibri-Bold"
1864 id="text482"
1865 class="st15 st38"
1866 x="222.5813"
1867 y="777.03638">Pi</text>
1868 <text
1869 style="font-size:10px;font-family:Calibri"
1870 id="text484"
1871 class="st17 st18"
1872 x="482.52859"
1873 y="702.16626">H</text>
1874 <text
1875 style="font-size:10px;font-family:Calibri"
1876 id="text486"
1877 class="st17 st18"
1878 x="444.9617"
1879 y="668.1311">H</text>
1880 <text
1881 style="font-size:16px;font-family:Calibri-Bold"
1882 id="text488"
1883 class="st15 st16"
1884 x="465.6225"
1885 y="1131.1801">NAD</text>
1886 <text
1887 style="font-size:16px;font-family:Calibri-Bold"
1888 id="text490"
1889 class="st15 st16"
1890 x="499.44772"
1891 y="1131.5101">QH</text>
1892 <text
1893 style="font-size:9.75px;font-family:Calibri-Bold"
1894 id="text492"
1895 class="st15 st40"
1896 x="520.51807"
1897 y="1134.7103">2</text>
1898 <text
1899 style="font-size:16px;font-family:Calibri-Bold"
1900 id="text494"
1901 class="st15 st16"
1902 x="396.8374"
1903 y="1133.059">5 H</text>
1904 <path
1905 style="fill:none;stroke:#000000;stroke-width:1.26660001"
1906 d="m 380.1998,1138.2711 0,17.7 133.5,0 0,-17.7 m -104.6,-1.6 0,18.7 m 26.7,-18.1 0,18.2 m 49,0 0,-17 m -13,17 0,28.6"
1907 class="st58"
1908 inkscape:connector-curvature="0"
1909 id="R_Complex1ROS"
1910 inkscape:label="#R_Complex1ROS" /><text
1911 style="font-size:16px;font-family:Calibri-Bold"
1912 id="text505"
1913 class="st15 st16"
1914 x="580.42444"
1915 y="1130.2744">2 Cytc-ox</text>
1916 <text
1917 style="font-size:16px;font-family:Calibri-Bold"
1918 id="text507"
1919 class="st15 st16"
1920 x="738.55164"
1921 y="1130.0198">2 Cytc-red</text>
1922 <text
1923 style="font-size:16px;font-family:Calibri-Bold"
1924 id="text509"
1925 class="st15 st16"
1926 x="834.18854"
1927 y="1130.3486">Q</text>
1928 <text
1929 style="font-size:16px;font-family:Calibri-Bold"
1930 id="text511"
1931 class="st15 st16"
1932 x="667.68347"
1933 y="1131.8838">2H</text>
1934 <text
1935 style="font-size:16px;font-family:Calibri-Bold"
1936 id="text513"
1937 class="st15 st16"
1938 x="702.59131"
1939 y="1130.5463">QH</text>
1940 <text
1941 style="font-size:9.75px;font-family:Calibri-Bold"
1942 id="text515"
1943 class="st15 st40"
1944 x="723.66162"
1945 y="1135.3677">2</text>
1946 <path
1947 style="fill:none;stroke:#000000;stroke-width:1.29487193"
1948 d="m 643.71124,1137.3649 0,18.3 195.54681,0 0,-18.3 m -159.78839,-0.3 0,18.2 m 41.6057,-17.5 0,17.4 m 65.782,0.1 0,-15.3 m -27.54973,15.6 0,24.5"
1949 class="st60"
1950 inkscape:connector-curvature="0"
1951 id="R_Complex3" /><text
1952 style="font-size:16px;font-family:Calibri-Bold"
1953 id="text518"
1954 class="st15 st16"
1955 x="746.68384"
1956 y="1199.0907">4 H</text>
1957 <text
1958 style="font-size:16px;font-family:Calibri-Bold"
1959 id="text520"
1960 class="st15 st16"
1961 x="888.39905"
1962 y="1132.1252">4 Cytc-red</text>
1963 <text
1964 style="font-size:16px;font-family:Calibri-Bold"
1965 id="text522"
1966 class="st15 st16"
1967 x="1039.7281"
1968 y="1131.0266">4 Cytc-ox</text>
1969 <text
1970 style="font-size:16px;font-family:Calibri-Bold"
1971 id="text524"
1972 class="st15 st16"
1973 x="1123.9191"
1974 y="1132.1672">2H</text>
1975 <text
1976 style="font-size:9.75px;font-family:Calibri-Bold"
1977 id="text526"
1978 class="st15 st40"
1979 x="1145.7395"
1980 y="1135.3684">2</text>
1981 <text
1982 style="font-size:16px;font-family:Calibri-Bold"
1983 id="text528"
1984 class="st15 st16"
1985 x="1150.6809"
1986 y="1132.1672">O</text>
1987 <text
1988 style="font-size:16px;font-family:Calibri-Bold"
1989 id="text530"
1990 class="st15 st16"
1991 x="981.8186"
1992 y="1132.9836">8H</text>
1993 <text
1994 style="font-size:16px;font-family:Calibri-Bold"
1995 id="text532"
1996 class="st15 st16"
1997 x="1011.5463"
1998 y="1132.6321">O</text>
1999 <text
2000 style="font-size:9.75px;font-family:Calibri-Bold"
2001 id="text534"
2002 class="st15 st40"
2003 x="1022.3666"
2004 y="1135.8323">2</text>
2005 <path
2006 style="fill:none;stroke:#000000;stroke-width:1.18280005"
2007 d="m 951.7,1138.8186 0,16.2 192.2,0 0,-16.2 m -152.2,-0.5 0,16.2 m 26.6,-15.7 0,15.8 m 53.3,-0.1 0,-13.8 m -23.8,13.8 0,25.4"
2008 class="st61"
2009 inkscape:connector-curvature="0"
2010 id="R_Complex4" /><text
2011 style="font-size:16px;font-family:Calibri-Bold"
2012 id="text537"
2013 class="st15 st16"
2014 x="1035.0892"
2015 y="1196.552">4 H</text>
2016 <text
2017 style="font-size:16px;font-family:Calibri-Bold"
2018 id="text539"
2019 class="st15 st16"
2020 x="890.96515"
2021 y="866.2962">CO</text>
2022 <text
2023 style="font-size:9.75px;font-family:Calibri-Bold"
2024 id="text541"
2025 class="st15 st40"
2026 x="910.13702"
2027 y="869.4964">2</text>
2028 <text
2029 style="font-size:16px;font-family:Calibri-Bold"
2030 id="text543"
2031 class="st15 st16"
2032 x="962.79913"
2033 y="866.07635">HCO</text>
2034 <text
2035 style="font-size:9.75px;font-family:Calibri-Bold"
2036 id="text545"
2037 class="st15 st40"
2038 x="992.0647"
2039 y="869.27655">3</text>
2040 <text
2041 style="font-size:9.75px;font-family:Calibri-Bold"
2042 id="text547"
2043 class="st15 st40"
2044 x="997.0061"
2045 y="857.27655">-</text>
2046 <path
2047 style="fill:none;stroke:#000000;stroke-width:2.06990004"
2048 d="m 929.8,861.11855 c -6.3,1.9 -5.8,15.6 -5.8,15.6 m 12.8,-15.5 c 6.4,1.4 4.8,12.8 4.8,12.8 m 11,-13 -36,-0.3"
2049 class="st62"
2050 inkscape:connector-curvature="0"
2051 id="R_CA5B_CA5A" /><text
2052 style="font-size:10px;font-family:Calibri"
2053 id="text550"
2054 class="st17 st18"
2055 x="938.54132"
2056 y="886.07739">H</text>
2057 <text
2058 style="font-size:10px;font-family:Calibri"
2059 id="text552"
2060 class="st17 st18"
2061 x="913.19171"
2062 y="885.12616">H</text>
2063 <text
2064 style="font-size:6.09369993px;font-family:Calibri"
2065 id="text554"
2066 class="st17 st26"
2067 x="919.42224"
2068 y="887.12616">2</text>
2069 <text
2070 style="font-size:10px;font-family:Calibri"
2071 id="text556"
2072 class="st17 st18"
2073 x="922.51105"
2074 y="885.12616">O</text>
2075 <path
2076 style="fill:none;stroke:#000000;stroke-width:2.18210006"
2077 d="m 1170.1,1230.7186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
2078 class="st14"
2079 inkscape:label="Glucose_DM_COOP b"
2080 inkscape:connector-curvature="0"
2081 id="B_Glucose_DM_COOP" /><path
2082 style="fill:none;stroke:#000000;stroke-width:2.18210006"
2083 d="m 1172.1,1229.4186 0.7,48.1"
2084 class="st14"
2085 inkscape:label="Glucose_DM_COOP"
2086 inkscape:connector-curvature="0"
2087 id="R_Glucose_DM_COOP" /><a
2088 transform="translate(1273.3622,1205.6018)"
2089 xlink:href="http://www.genome.jp/dbget-bin/www_bget?cpd:C00031"
2090 id="a14384-0"><text
2091 style="font-size:16px;font-family:Calibri-Bold"
2092 id="text561"
2093 class="st15 st16"
2094 transform="translate(-116.0982,12.7041)">Glc</text>
2095 </a><path
2096 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2097 d="m 501.1,1274.6186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
2098 class="st63"
2099 inkscape:label="Ex_SC_H2O f"
2100 inkscape:connector-curvature="0"
2101 id="F_Ex_SC_H2O" /><path
2102 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2103 d="m 503.2,1227.4186 0,47.6"
2104 class="st63"
2105 inkscape:label="Ex_SC_H2O"
2106 inkscape:connector-curvature="0"
2107 id="R_Ex_SC_H2O" /><text
2108 style="font-size:16px;font-family:Calibri-Bold"
2109 id="text565"
2110 class="st15 st16"
2111 x="488.92899"
2112 y="1219.1184">H</text>
2113 <text
2114 style="font-size:9.75px;font-family:Calibri-Bold"
2115 id="text567"
2116 class="st15 st40"
2117 x="499.02267"
2118 y="1222.3176">2</text>
2119 <text
2120 style="font-size:16px;font-family:Calibri-Bold"
2121 id="text569"
2122 class="st15 st16"
2123 x="503.96512"
2124 y="1219.1184">O</text>
2125 <path
2126 style="fill:none;stroke:#000000;stroke-width:2.67510009"
2127 d="m 561.7,1232.4186 -2.2,-7.1 -2.2,7.1 2.2,-1.8 2.2,1.8 z"
2128 class="st64"
2129 inkscape:label="Ex_O2 b"
2130 inkscape:connector-curvature="0"
2131 id="B_Ex_O2" /><path
2132 style="fill:none;stroke:#000000;stroke-width:2.67510009"
2133 d="m 559.6,1278.6186 0,-46.6"
2134 class="st64"
2135 inkscape:label="Ex_O2"
2136 inkscape:connector-curvature="0"
2137 id="R_Ex_O2" /><text
2138 style="font-size:16px;font-family:Calibri-Bold"
2139 id="text573"
2140 class="st15 st16"
2141 x="553.19659"
2142 y="1218.1301">O</text>
2143 <text
2144 style="font-size:9.75px;font-family:Calibri-Bold"
2145 id="text575"
2146 class="st15 st40"
2147 x="564.01691"
2148 y="1221.3303">2</text>
2149 <path
2150 style="fill:none;stroke:#000000;stroke-width:2.18210006"
2151 d="m 1236.1431,1273.3107 -2.2,7.3 -2.2,-7.3 2.2,1.8 2.2,-1.8 z"
2152 class="st14"
2153 inkscape:label="Glutamine_DM_COOP f"
2154 inkscape:connector-curvature="0"
2155 id="F_Glutamine_DM_COOP" /><text
2156 style="font-size:16px;font-family:Calibri-Bold"
2157 id="text579"
2158 class="st15 st16"
2159 x="1219.5931"
2160 y="1218.3059">Gln</text>
2161 <path
2162 style="fill:none;stroke:#000000;stroke-width:3.16359997"
2163 d="m 643.8,1274.6186 2.2,6.9 2.2,-6.9 -2.2,1.7 -2.2,-1.7 z"
2164 class="st65"
2165 inkscape:label="forward Ex_NH3 "
2166 inkscape:connector-curvature="0"
2167 id="F_Ex_NH3" /><path
2168 style="fill:none;stroke:#000000;stroke-width:3.36989999"
2169 d="m 645.9,1223.3186 0,51.7"
2170 class="st66"
2171 inkscape:label="Ex_NH3 "
2172 inkscape:connector-curvature="0"
2173 id="R_Ex_NH3" /><text
2174 style="font-size:16px;font-family:Calibri-Bold"
2175 id="text583"
2176 class="st15 st16"
2177 x="635.18091"
2178 y="1219.1711">NH</text>
2179 <text
2180 style="font-size:9.75px;font-family:Calibri-Bold"
2181 id="text585"
2182 class="st15 st40"
2183 x="655.81384"
2184 y="1222.3713">3</text>
2185 <path
2186 style="fill:none;stroke:#000000;stroke-width:2.18210006"
2187 d="m 841.2,1232.3186 2.2,-7.3 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
2188 class="st14"
2189 inkscape:label="DM_Folate f"
2190 inkscape:connector-curvature="0"
2191 id="F_DM_Folate" /><path
2192 style="fill:none;stroke:#000000;stroke-width:2.18210006"
2193 d="m 843.5,1276.7186 -0.3,-48.1"
2194 class="st14"
2195 inkscape:label="DM_Folate"
2196 inkscape:connector-curvature="0"
2197 id="R_DM_Folate" /><text
2198 style="font-size:16px;font-family:Calibri-Bold"
2199 id="text589"
2200 class="st15 st16"
2201 x="821.54034"
2202 y="1218.8098">Folate</text>
2203 <path
2204 style="fill:none;stroke:#000000;stroke-width:2.31469989"
2205 d="m 689.2,1223.4186 0,56.6"
2206 class="st67"
2207 inkscape:label="DM_Urea"
2208 inkscape:connector-curvature="0"
2209 id="R_DM_Urea" /><text
2210 style="font-size:16px;font-family:Calibri-Bold"
2211 id="text592"
2212 class="st15 st16"
2213 x="672.34991"
2214 y="1218.9426">Urea</text>
2215 <path
2216 style="fill:none;stroke:#000000;stroke-width:2.22029996"
2217 d="m 890.5,1223.6186 0.3,50.4"
2218 class="st68"
2219 inkscape:label="DM_putrescine"
2220 inkscape:connector-curvature="0"
2221 id="R_DM_putrescine" /><text
2222 style="font-size:16px;font-family:Calibri-Bold"
2223 id="text595"
2224 class="st15 st16"
2225 x="873.35284"
2226 y="1219.4836">Putr</text>
2227 <text
2228 style="font-size:16px;font-family:Calibri-Bold"
2229 id="text597"
2230 class="st15 st16"
2231 x="1115.0238"
2232 y="1218.8967">Lact</text>
2233 <path
2234 style="fill:none;stroke:#000000;stroke-width:2.22930002"
2235 d="m 1141.3465,1230.8815 -2.2,-7.7 -2.2,7.7 2.2,-1.9 2.2,1.9 z"
2236 class="st69"
2237 inkscape:label="LactateL_DM_COOP b"
2238 inkscape:connector-curvature="0"
2239 id="B_LactateL_DM_COOP" /><path
2240 style="fill:none;stroke:#000000;stroke-width:2.18210006"
2241 d="m 501.1,1232.3186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
2242 class="st14"
2243 inkscape:label="Ex_SC_H2O b"
2244 inkscape:connector-curvature="0"
2245 id="B_Ex_SC_H2O" /><path
2246 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2247 d="m 532.3,1274.6186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
2248 class="st63"
2249 inkscape:label="forward Ex_SC_H "
2250 inkscape:connector-curvature="0"
2251 id="F_Ex_SC_H" /><path
2252 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2253 d="m 534.4,1227.4186 0,47.6"
2254 class="st63"
2255 inkscape:label="Ex_SC_Hs"
2256 inkscape:connector-curvature="0"
2257 id="R_Ex_SC_Hs" /><text
2258 style="font-size:16px;font-family:Calibri-Bold"
2259 id="text604"
2260 class="st15 st16"
2261 x="529.56775"
2262 y="1219.1184">H</text>
2263 <path
2264 style="fill:none;stroke:#000000;stroke-width:2.18210006"
2265 d="m 532.3,1232.3186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
2266 class="st14"
2267 inkscape:label="backward Ex_SC_H "
2268 inkscape:connector-curvature="0"
2269 id="B_Ex_SC_H" /><path
2270 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2271 d="m 687.5,1275.3186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
2272 class="st63"
2273 inkscape:label="DM_Urea f"
2274 inkscape:connector-curvature="0"
2275 id="F_DM_Urea" /><path
2276 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2277 d="m 888.7,1273.2186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
2278 class="st63"
2279 inkscape:label="DM_putrescine f"
2280 inkscape:connector-curvature="0"
2281 id="F_DM_putrescine" /><text
2282 style="font-size:16px;font-family:Calibri-Bold"
2283 id="text609"
2284 class="st15 st16"
2285 x="1258.4867"
2286 y="1218.8098">Glu</text>
2287 <path
2288 style="fill:none;stroke:#000000;stroke-width:2.22930002"
2289 d="m 1267.4,1273.3186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
2290 class="st69"
2291 inkscape:label="Glutamate_DM_COOP f"
2292 inkscape:connector-curvature="0"
2293 id="F_Glutamate_DM_COOP" /><path
2294 style="fill:none;stroke:#000000;stroke-width:2.22930002"
2295 d="m 1270,1225.4186 0,50.5"
2296 class="st69"
2297 inkscape:label="Glutamate_DM_COOP"
2298 inkscape:connector-curvature="0"
2299 id="R_Glutamate_DM_COOP" /><text
2300 style="font-size:16px;font-family:Calibri-Bold"
2301 id="text613"
2302 class="st15 st16"
2303 x="1294.558"
2304 y="1219.0598">Arg</text>
2305 <path
2306 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2307 d="m 1305.8,1231.5186 2.2,1.8 -2.2,-7.2 -2.2,7.2 2.2,-1.8 z"
2308 class="st63"
2309 inkscape:label="Arginine_DM_COOP f"
2310 inkscape:connector-curvature="0"
2311 id="F_Arginine_DM_COOP" /><text
2312 style="font-size:16px;font-family:Calibri-Bold"
2313 id="text616"
2314 class="st15 st16"
2315 x="577.40161"
2316 y="1218.1838">CO</text>
2317 <text
2318 style="font-size:9.75px;font-family:Calibri-Bold"
2319 id="text618"
2320 class="st15 st40"
2321 x="598.57355"
2322 y="1221.384">2</text>
2323 <path
2324 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2325 d="m 590,1229.9186 0,47.6"
2326 class="st63"
2327 inkscape:label="DM_CO2c"
2328 inkscape:connector-curvature="0"
2329 id="R_DM_CO2c" /><text
2330 style="font-size:16px;font-family:Calibri-Bold"
2331 id="text622"
2332 class="st15 st16"
2333 x="615.26984"
2334 y="1219.7141">Pi</text>
2335 <path
2336 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2337 d="m 620.5,1233.9186 0,47.6"
2338 class="st63"
2339 inkscape:label="Ex_SC_Pi "
2340 inkscape:connector-curvature="0"
2341 id="R_Ex_SC_Pi" /><path
2342 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2343 d="m 620.6,1232.5186 2.2,1.8 -2.2,-7.2 -2.2,7.2 2.2,-1.8 z"
2344 class="st63"
2345 inkscape:label="Ex_SC_Pi b"
2346 inkscape:connector-curvature="0"
2347 id="B_Ex_SC_Pi" /><path
2348 style="fill:none;stroke:#000000;stroke-width:1.96669996"
2349 d="m 587.5,1271.4186 1.9,6.8 1.9,-6.8 -1.9,1.7 -1.9,-1.7 z"
2350 class="st70"
2351 inkscape:label="FORWARD DM_CO2c"
2352 inkscape:connector-curvature="0"
2353 id="F_DM_CO2c" /><path
2354 style="fill:none;stroke:#000000;stroke-width:2.22930002"
2355 d="m 618.6,1275.0186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
2356 class="st69"
2357 inkscape:label="Ex_SC_Pi f"
2358 inkscape:connector-curvature="0"
2359 id="F_Ex_SC_Pi" /><path
2360 style="fill:none;stroke:#000000;stroke-width:2.13409996"
2361 d="m 927.4,1281.5186 -0.8,-56.3"
2362 class="st71"
2363 inkscape:label="DM_guanidinoacetatec"
2364 inkscape:connector-curvature="0"
2365 id="R_DM_guanidinoacetatec" /><path
2366 style="fill:none;stroke:#000000;stroke-width:2.17810011"
2367 d="m 927.19047,1278.0186 -2.3,-1.7 2.4,7.2 2,-7.3 -2.1,1.8 z"
2368 class="st63"
2369 inkscape:label="DM_guanidinoacetatec f"
2370 inkscape:connector-curvature="0"
2371 id="F_DM_guanidinoacetatec" /><text
2372 style="font-size:15.99923611px;font-family:Calibri-Bold"
2373 id="text630"
2374 class="st15 st16"
2375 transform="matrix(0.99984771,-0.01745156,0.01745156,0.99984771,0,0)"
2376 x="896.45245"
2377 y="1235.1273">GA</text>
2378 <text
2379 style="font-size:10px;font-family:Calibri"
2380 id="text632"
2381 class="st17 st18"
2382 x="813.1839"
2383 y="294.34796">Asp</text>
2384 <text
2385 style="font-size:10px;font-family:Calibri"
2386 id="text634"
2387 class="st17 st18"
2388 x="847.99152"
2389 y="294.67303">2 ATP</text>
2390 <text
2391 style="font-size:10px;font-family:Calibri"
2392 id="text636"
2393 class="st17 st18"
2394 x="838.64294"
2395 y="261.41425">QH</text>
2396 <text
2397 style="font-size:6.09369993px;font-family:Calibri"
2398 id="text638"
2399 class="st17 st26"
2400 x="851.60181"
2401 y="263.41425">2</text>
2402 <text
2403 style="font-size:10px;font-family:Calibri"
2404 id="text640"
2405 class="st17 st18"
2406 x="859.31573"
2407 y="261.81076">2 ADP</text>
2408 <text
2409 style="font-size:16px;font-family:Calibri-Bold"
2410 id="text642"
2411 class="st15 st16"
2412 x="950.24341"
2413 y="283.13986">UMP</text>
2414 <text
2415 style="font-size:10px;font-family:Calibri"
2416 id="text644"
2417 class="st17 st18"
2418 x="792.67413"
2419 y="295.08524">Gln</text>
2420 <text
2421 style="font-size:10px;font-family:Calibri"
2422 id="text646"
2423 class="st17 st18"
2424 x="800.29321"
2425 y="261.82446">Glu</text>
2426 <text
2427 style="font-size:10px;font-family:Calibri"
2428 id="text648"
2429 class="st17 st18"
2430 x="886.02863"
2431 y="294.47684">HCO</text>
2432 <text
2433 style="font-size:6.09369993px;font-family:Calibri"
2434 id="text650"
2435 class="st17 st26"
2436 x="904.12433"
2437 y="296.47684">3</text>
2438 <text
2439 style="font-size:6.09369993px;font-family:Calibri"
2440 id="text652"
2441 class="st17 st26"
2442 x="907.2132"
2443 y="288.97684">-</text>
2444 <text
2445 style="font-size:10px;font-family:Calibri"
2446 id="text654"
2447 class="st17 st18"
2448 x="835.15265"
2449 y="294.92795">Q</text>
2450 <text
2451 style="font-size:10px;font-family:Calibri"
2452 id="text656"
2453 class="st17 st18"
2454 x="875.8938"
2455 y="294.94363">H</text>
2456 <text
2457 style="font-size:10px;font-family:Calibri"
2458 id="text658"
2459 class="st17 st18"
2460 x="906.9231"
2461 y="262.21405">PPi</text>
2462 <text
2463 style="font-size:16px;font-family:Calibri-Bold"
2464 id="text660"
2465 class="st15 st16"
2466 x="953.64874"
2467 y="337.59396">UDP</text>
2468 <text
2469 style="font-size:10px;font-family:Calibri"
2470 id="text662"
2471 class="st17 st18"
2472 x="995.4729"
2473 y="301.37915">ATP</text>
2474 <text
2475 style="font-size:10px;font-family:Calibri"
2476 id="text664"
2477 class="st17 st18"
2478 x="985.13312"
2479 y="312.31955">ADP</text>
2480 <path
2481 style="fill:none;stroke:#000000;stroke-width:1.5819"
2482 d="m 937.8,332.81855 c -4.7,-0.3 -6.5,-11.7 -6.5,-11.7 m 21.4,11.5 -31.2,0.2"
2483 class="st72"
2484 inkscape:label="RRM2B_TXN_RRM1_RRM2_1"
2485 inkscape:connector-curvature="0"
2486 id="R_RRM2B_TXN_RRM1_RRM2_1" /><text
2487 style="font-size:16px;font-family:Calibri-Bold"
2488 id="text667"
2489 class="st15 st16"
2490 x="872.57452"
2491 y="337.33325">dUDP</text>
2492 <text
2493 style="font-size:10px;font-family:Calibri"
2494 id="text669"
2495 class="st17 st18"
2496 x="920.89093"
2497 y="314.44846">H</text>
2498 <text
2499 style="font-size:6.09369993px;font-family:Calibri"
2500 id="text671"
2501 class="st17 st26"
2502 x="927.1214"
2503 y="316.44846">2</text>
2504 <text
2505 style="font-size:10px;font-family:Calibri"
2506 id="text673"
2507 class="st17 st18"
2508 x="930.21021"
2509 y="314.44846">O</text>
2510 <text
2511 style="font-size:16.00037575px;font-family:Calibri-Bold"
2512 id="text675"
2513 class="st15 st16"
2514 transform="matrix(0.99997657,-0.0068447,0.0068447,0.99997657,0,0)"
2515 x="779.65546"
2516 y="343.09702">dUMP</text>
2517 <text
2518 style="font-size:10px;font-family:Calibri"
2519 id="text677"
2520 class="st17 st18"
2521 transform="matrix(0.99990048,0.01410788,-0.01410788,0.99990048,0,0)"
2522 x="852.72308"
2523 y="304.24103">ADP</text>
2524 <text
2525 style="font-size:10px;font-family:Calibri"
2526 id="text679"
2527 class="st17 st18"
2528 transform="matrix(0.9998951,-0.01448404,0.01448404,0.9998951,0,0)"
2529 x="827.13593"
2530 y="328.46188">ATP</text>
2531 <text
2532 style="font-size:10px;font-family:Calibri"
2533 id="text681"
2534 class="st17 st18"
2535 x="923.82745"
2536 y="262.21405">CO</text>
2537 <text
2538 style="font-size:6.09369993px;font-family:Calibri"
2539 id="text683"
2540 class="st17 st26"
2541 x="935.69275"
2542 y="264.21405">2</text>
2543 <text
2544 style="font-size:16.0006218px;font-family:Calibri-Bold"
2545 id="text685"
2546 class="st15 st16"
2547 transform="matrix(0.99976114,-0.02185571,0.02185571,0.99976114,0,0)"
2548 x="673.61633"
2549 y="353.25659">dTMP</text>
2550 <text
2551 style="font-size:10.00026512px;font-family:Calibri"
2552 id="text687"
2553 class="st17 st18"
2554 transform="matrix(0.99997352,-0.00727731,0.00727731,0.99997352,0,0)"
2555 x="748.1861"
2556 y="319.31909">meTHF</text>
2557 <text
2558 style="font-size:10.00010777px;font-family:Calibri"
2559 id="text689"
2560 class="st17 st18"
2561 transform="matrix(0.99998921,0.00464547,-0.00464547,0.99998921,0,0)"
2562 x="731.41992"
2563 y="310.3287">DHF</text>
2564 <text
2565 style="font-size:16px;font-family:Calibri-Bold"
2566 id="text691"
2567 class="st15 st16"
2568 x="1025.2386"
2569 y="337.24924">UTP</text>
2570 <text
2571 style="font-size:16px;font-family:Calibri-Bold"
2572 id="text693"
2573 class="st15 st16"
2574 x="1113.8793"
2575 y="337.43964">CTP</text>
2576 <text
2577 style="font-size:10px;font-family:Calibri"
2578 id="text695"
2579 class="st17 st18"
2580 x="1079.4359"
2581 y="317.43384">ADP+Pi</text>
2582 <text
2583 style="font-size:10px;font-family:Calibri"
2584 id="text697"
2585 class="st17 st18"
2586 x="1039.0609"
2587 y="317.67896">ATP+NH</text>
2588 <text
2589 style="font-size:6.09369993px;font-family:Calibri"
2590 id="text699"
2591 class="st17 st26"
2592 x="1071.7709"
2593 y="319.67896">3</text>
2594 <text
2595 style="font-size:10px;font-family:Calibri"
2596 id="text701"
2597 class="st17 st18"
2598 x="1163.5892"
2599 y="316.63016">ATP</text>
2600 <text
2601 style="font-size:10px;font-family:Calibri"
2602 id="text703"
2603 class="st17 st18"
2604 x="1144.7562"
2605 y="317.36545">ADP</text>
2606 <text
2607 style="font-size:16px;font-family:Calibri-Bold"
2608 id="text705"
2609 class="st15 st16"
2610 x="1185.2777"
2611 y="337.33524">CDP</text>
2612 <path
2613 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2614 d="m 1157.5,324.71855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m -7,5.6 c -7.4,1.9 -7.4,1.9 -7.4,1.9 l 7.2,2.4 -1.8,-2.2 2,-2.1 z"
2615 class="st73"
2616 inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4"
2617 inkscape:connector-curvature="0"
2618 id="B_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4" /><path
2619 style="fill:none;stroke:#000000;stroke-width:2.5"
2620 d="m 1174.1,335.71855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -3.6,-10.9 c -1.1,-5.1 -1.1,-5.1 -1.1,-5.1 l -1.7,5 1.5,-1.2 1.3,1.3 z"
2621 class="st22"
2622 inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4"
2623 inkscape:connector-curvature="0"
2624 id="F_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4" /><text
2625 style="font-size:16px;font-family:Calibri-Bold"
2626 id="text709"
2627 class="st15 st16"
2628 x="1258.7123"
2629 y="337.35764">CMP</text>
2630 <path
2631 style="fill:none;stroke:#000000;stroke-width:2.43479991"
2632 d="m 1198.8,339.01855 -0.1,22.4 m -0.1,-17.5 c -0.2,5.3 -9.5,7.3 -9.5,7.3"
2633 class="st74"
2634 inkscape:connector-curvature="0"
2635 id="R_RRM2B_TXN_RRM1_RRM2_2" /><text
2636 style="font-size:10px;font-family:Calibri"
2637 id="text712"
2638 class="st17 st18"
2639 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2640 x="1168.255"
2641 y="353.44818">H</text>
2642 <text
2643 style="font-size:6.09369993px;font-family:Calibri"
2644 id="text714"
2645 class="st17 st26"
2646 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2647 x="1174.4854"
2648 y="355.44815">2</text>
2649 <text
2650 style="font-size:10px;font-family:Calibri"
2651 id="text716"
2652 class="st17 st18"
2653 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2654 x="1177.5743"
2655 y="353.44812">O</text>
2656 <text
2657 style="font-size:16px;font-family:Calibri-Bold"
2658 id="text718"
2659 class="st15 st16"
2660 x="1175.5306"
2661 y="382.04416">dCDP</text>
2662 <text
2663 style="font-size:16px;font-family:Calibri-Bold"
2664 id="text720"
2665 class="st15 st16"
2666 x="360.74741"
2667 y="449.50314">3PPyr</text>
2668 <text
2669 style="font-size:10px;font-family:Calibri"
2670 id="text722"
2671 class="st17 st18"
2672 x="410.62479"
2673 y="426.49734">NADH</text>
2674 <text
2675 style="font-size:10px;font-family:Calibri"
2676 id="text724"
2677 class="st17 st18"
2678 x="435.24878"
2679 y="426.49734">+</text>
2680 <text
2681 style="font-size:10px;font-family:Calibri"
2682 id="text726"
2683 class="st17 st18"
2684 x="440.22931"
2685 y="426.49734">H</text>
2686 <path
2687 style="fill:none;stroke:#000000;stroke-width:2.33130002"
2688 d="m 446.2,443.81855 -34.2,0.2 m 20.4,0.1 c -4.3,-0.3 -6,-12.3 -6,-12.3 m 3.8,12.1 c 6.1,1.5 5.6,12.5 5.6,12.5"
2689 class="st75"
2690 inkscape:label="PHGDH_UBAC2 "
2691 inkscape:connector-curvature="0"
2692 id="R_PHGDH_UBAC2" /><text
2693 style="font-size:10px;font-family:Calibri"
2694 id="text729"
2695 class="st17 st18"
2696 x="427.62769"
2697 y="465.14575">NAD</text>
2698 <text
2699 style="font-size:15.99982166px;font-family:Calibri-Bold"
2700 id="text731"
2701 class="st15 st16"
2702 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2703 x="356.75916"
2704 y="399.59976">3PSer</text>
2705 <text
2706 style="font-size:10px;font-family:Calibri"
2707 id="text733"
2708 class="st17 st18"
2709 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2710 x="345.07333"
2711 y="429.83682">Glu</text>
2712 <text
2713 style="font-size:9.99962234px;font-family:Calibri"
2714 id="text735"
2715 class="st17 st18"
2716 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
2717 x="333.53885"
2718 y="420.90979">AKG</text>
2719 <path
2720 style="fill:none;stroke:#000000;stroke-width:2.0948"
2721 d="m 377,437.71855 -0.2,-34.2 m -15.7,11.7 c 9.7,-2.9 16,3.2 16,3.2 m -0.2,3.4 c -1.4,5.3 -16.7,5.1 -16.7,5.1"
2722 class="st76"
2723 inkscape:connector-curvature="0"
2724 id="R_PSAT1" /><path
2725 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2726 d="m 379.1,403.81855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -14,12.2 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
2727 class="st73"
2728 inkscape:connector-curvature="0"
2729 id="F_PSAT1" /><path
2730 style="fill:none;stroke:#000000;stroke-width:2.23519993"
2731 d="m 379.2,351.31855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z"
2732 class="st77"
2733 inkscape:label="VPS29_PSPH_PSPHP1 forward"
2734 inkscape:connector-curvature="0"
2735 id="F_VPS29_PSPH_PSPHP1" /><text
2736 style="font-size:15.99982166px;font-family:Calibri-Bold"
2737 id="text740"
2738 class="st15 st16"
2739 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2740 x="359.90805"
2741 y="346.62714">Ser</text>
2742 <text
2743 style="font-size:10px;font-family:Calibri"
2744 id="text742"
2745 class="st17 st18"
2746 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2747 x="393.64661"
2748 y="374.83282">H</text>
2749 <text
2750 style="font-size:6.09369993px;font-family:Calibri"
2751 id="text744"
2752 class="st17 st26"
2753 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2754 x="399.87701"
2755 y="376.83292">2</text>
2756 <text
2757 style="font-size:10px;font-family:Calibri"
2758 id="text746"
2759 class="st17 st18"
2760 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2761 x="402.96588"
2762 y="374.83289">O</text>
2763 <text
2764 style="font-size:9.99962234px;font-family:Calibri"
2765 id="text748"
2766 class="st17 st18"
2767 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
2768 x="395.1853"
2769 y="368.10416">Pi</text>
2770 <path
2771 style="fill:none;stroke:#000000;stroke-width:2.0948"
2772 d="m 377,367.81855 c 0.6,2.3 3,3.4 5.1,4.1 2.9,0.8 6,1.1 9,1.1 m 1.7,-11.8 c -5.4,-1.7 -11.7,-0.5 -16,3.2 m 0.3,19.3 c -0.1,-11.4 -0.1,-22.8 -0.2,-34.2"
2773 class="st76"
2774 inkscape:label="VPS29_PSPH_PSPHP1 "
2775 inkscape:connector-curvature="0"
2776 id="R_VPS29_PSPH_PSPHP1" /><text
2777 style="font-size:15.99982166px;font-family:Calibri-Bold"
2778 id="text751"
2779 class="st15 st16"
2780 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2781 x="360.82996"
2782 y="259.71588">Gly</text>
2783 <text
2784 style="font-size:10px;font-family:Calibri"
2785 id="text753"
2786 class="st17 st18"
2787 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2788 x="399.81461"
2789 y="284.13171">THF</text>
2790 <path
2791 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2792 d="m 390.2,284.61855 c 7,-1.3 7,-1.3 7,-1.3 l -6.8,-1.9 1.7,1.7 -1.9,1.5 z m -15.6,36.9 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z"
2793 class="st73"
2794 inkscape:connector-curvature="0"
2795 id="B_SHMT1" /><path
2796 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2797 d="m 425.5,435.31855 c -0.5,-7.1 -0.5,-7.1 -0.5,-7.1 l 3.5,6.2 -2,-1.2 -1,2.1 z m -11.7,11 c -6.3,-2.2 -6.3,-2.2 -6.3,-2.2 l 6.5,-1.7 -1.7,1.9 1.5,2 z"
2798 class="st73"
2799 inkscape:label="PHGDH_UBAC2 forward"
2800 inkscape:connector-curvature="0"
2801 id="F_PHGDH_UBAC2" /><text
2802 style="font-size:16px;font-family:Calibri-Bold"
2803 id="text757"
2804 class="st15 st16"
2805 x="422.2869"
2806 y="341.40353">Pyr</text>
2807 <text
2808 style="font-size:10px;font-family:Calibri"
2809 id="text759"
2810 class="st17 st18"
2811 x="396.70538"
2812 y="319.50906">NH</text>
2813 <text
2814 style="font-size:6.09369993px;font-family:Calibri"
2815 id="text761"
2816 class="st17 st26"
2817 x="409.3909"
2818 y="321.50906">3</text>
2819 <path
2820 style="fill:none;stroke:#000000;stroke-width:2.38170004"
2821 d="m 398.5,338.71855 c 3.7,-0.3 5.1,-10.5 5.1,-10.5 m -16.8,10.6 26.2,-0.2"
2822 class="st78"
2823 inkscape:connector-curvature="0"
2824 id="R_SDS_SDSL_SRR" /><text
2825 style="font-size:15.99982166px;font-family:Calibri-Bold"
2826 id="text764"
2827 class="st15 st16"
2828 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2829 x="141.05353"
2830 y="304.02942">DHF</text>
2831 <text
2832 style="font-size:15.99982166px;font-family:Calibri-Bold"
2833 id="text766"
2834 class="st15 st16"
2835 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2836 x="136.36797"
2837 y="245.96878">Folate</text>
2838 <path
2839 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2840 d="m 158.1,279.71855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m 14.1,-2.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
2841 class="st73"
2842 inkscape:label="DHFRL1_DHFR_2 forward"
2843 inkscape:connector-curvature="0"
2844 id="F_DHFRL1_DHFR_2" /><path
2845 style="fill:none;stroke:#000000;stroke-width:2.29760003"
2846 d="m 159.9,281.31855 -0.2,-34.2 m 15.9,8.5 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.3,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
2847 class="st79"
2848 inkscape:label="DHFRL1_DHFR_2 "
2849 inkscape:connector-curvature="0"
2850 id="R_DHFRL1_DHFR_2" /><text
2851 style="font-size:10px;font-family:Calibri"
2852 id="text770"
2853 class="st17 st18"
2854 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2855 x="184.45857"
2856 y="280.61414">NADP</text>
2857 <text
2858 style="font-size:9.99962234px;font-family:Calibri"
2859 id="text772"
2860 class="st17 st18"
2861 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
2862 x="179.325"
2863 y="260.32965">NADPH</text>
2864 <text
2865 style="font-size:9.99962234px;font-family:Calibri"
2866 id="text774"
2867 class="st17 st18"
2868 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
2869 x="179.32498"
2870 y="272.82965">+H</text>
2871 <text
2872 style="font-size:15.99982166px;font-family:Calibri-Bold"
2873 id="text776"
2874 class="st15 st16"
2875 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2876 x="141.77278"
2877 y="368.62994">THF</text>
2878 <path
2879 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2880 d="m 157.7,343.41855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m 14.1,-2.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
2881 class="st73"
2882 inkscape:label="DHFRL1_DHFR_4 forward"
2883 inkscape:connector-curvature="0"
2884 id="F_DHFRL1_DHFR_4" /><path
2885 style="fill:none;stroke:#000000;stroke-width:2.29760003"
2886 d="m 159.5,345.01855 -0.2,-34.2 m 15.9,8.5 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.2,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
2887 class="st79"
2888 inkscape:label="DHFRL1_DHFR_4 "
2889 inkscape:connector-curvature="0"
2890 id="R_DHFRL1_DHFR_4" /><path
2891 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2892 d="m 161.5,312.61855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m 9.7,7.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
2893 class="st73"
2894 inkscape:label="DHFRL1_DHFR_4 "
2895 inkscape:connector-curvature="0"
2896 id="B_DHFRL1_DHFR_4" /><text
2897 style="font-size:10px;font-family:Calibri"
2898 id="text781"
2899 class="st17 st18"
2900 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2901 x="181.55092"
2902 y="341.92856">NADP</text>
2903 <text
2904 style="font-size:9.99962234px;font-family:Calibri"
2905 id="text783"
2906 class="st17 st18"
2907 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
2908 x="177.77963"
2909 y="322.29248">NADPH</text>
2910 <text
2911 style="font-size:9.99962234px;font-family:Calibri"
2912 id="text785"
2913 class="st17 st18"
2914 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
2915 x="177.77962"
2916 y="334.79254">+H</text>
2917 <text
2918 style="font-size:15.99982166px;font-family:Calibri-Bold"
2919 id="text787"
2920 class="st15 st16"
2921 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2922 x="122.12817"
2923 y="433.13483">10-formyl</text>
2924 <text
2925 style="font-size:15.99982166px;font-family:Calibri-Bold"
2926 id="text789"
2927 class="st15 st16"
2928 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
2929 x="141.62041"
2930 y="453.13483">THF</text>
2931 <path
2932 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2933 d="m 157.3,407.81855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m 14.1,-2.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
2934 class="st73"
2935 inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297 foward"
2936 inkscape:connector-curvature="0"
2937 id="F_MTHFD1_AL445665_1_AQP7P4_LOC286297" /><path
2938 style="fill:none;stroke:#000000;stroke-width:2.29760003"
2939 d="m 159,409.41855 -0.2,-34.2 m 15.9,8.5 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.3,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
2940 class="st79"
2941 inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297 "
2942 inkscape:connector-curvature="0"
2943 id="R_MTHFD1_AL445665_1_AQP7P4_LOC286297" /><path
2944 style="fill:none;stroke:#000000;stroke-width:2.09949994"
2945 d="m 161.1,377.01855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m 9.7,7.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
2946 class="st73"
2947 inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297 backward"
2948 inkscape:connector-curvature="0"
2949 id="B_MTHFD1_AL445665_1_AQP7P4_LOC286297" /><text
2950 style="font-size:10px;font-family:Calibri"
2951 id="text794"
2952 class="st17 st18"
2953 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2954 x="181.41222"
2955 y="406.33478">ADP</text>
2956 <text
2957 style="font-size:10px;font-family:Calibri"
2958 id="text796"
2959 class="st17 st18"
2960 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2961 x="198.51668"
2962 y="406.33478">+</text>
2963 <text
2964 style="font-size:10px;font-family:Calibri"
2965 id="text798"
2966 class="st17 st18"
2967 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2968 x="203.49713"
2969 y="406.33481">Pi</text>
2970 <text
2971 style="font-size:9.99962234px;font-family:Calibri"
2972 id="text800"
2973 class="st17 st18"
2974 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
2975 x="176.62868"
2976 y="387.771">for+ATP</text>
2977 <path
2978 style="fill:none;stroke:#000000;stroke-width:2.29760003"
2979 d="m 221.4,395.51855 c 1.4,5.3 17.3,5.1 17.3,5.1 m -1.6,-19.7 c -9.7,-2.9 -16,3.2 -16,3.2 m -14.9,44.3 14.4,0 0,-68 -39.6,0"
2980 class="st79"
2981 inkscape:label="MTHFD1_3 "
2982 inkscape:connector-curvature="0"
2983 id="R_MTHFD1_3" /><text
2984 style="font-size:10px;font-family:Calibri"
2985 id="text803"
2986 class="st17 st18"
2987 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2988 x="250.68755"
2989 y="398.89441">NADP</text>
2990 <text
2991 style="font-size:10px;font-family:Calibri"
2992 id="text805"
2993 class="st17 st18"
2994 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
2995 x="274.24716"
2996 y="398.89441">+</text>
2997 <text
2998 style="font-size:10px;font-family:Calibri"
2999 id="text807"
3000 class="st17 st18"
3001 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3002 x="250.68761"
3003 y="411.39444">H</text>
3004 <text
3005 style="font-size:6.09369993px;font-family:Calibri"
3006 id="text809"
3007 class="st17 st26"
3008 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3009 x="256.91809"
3010 y="413.39441">2</text>
3011 <text
3012 style="font-size:10px;font-family:Calibri"
3013 id="text811"
3014 class="st17 st18"
3015 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3016 x="260.00687"
3017 y="411.39438">O</text>
3018 <text
3019 style="font-size:9.99962234px;font-family:Calibri"
3020 id="text813"
3021 class="st17 st18"
3022 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3023 x="242.4368"
3024 y="378.47998">NADPH+</text>
3025 <text
3026 style="font-size:9.99962234px;font-family:Calibri"
3027 id="text815"
3028 class="st17 st18"
3029 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3030 x="242.43677"
3031 y="390.98007">H+CO</text>
3032 <text
3033 style="font-size:6.09346962px;font-family:Calibri"
3034 id="text817"
3035 class="st17 st26"
3036 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3037 x="265.513"
3038 y="392.98007">2</text>
3039 <text
3040 style="font-size:15.99982166px;font-family:Calibri-Bold"
3041 id="text819"
3042 class="st15 st16"
3043 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
3044 x="261.84116"
3045 y="348.57727">mTHF</text>
3046 <path
3047 style="fill:none;stroke:#000000;stroke-width:2.09509993"
3048 d="m 204.8,436.41855 79.8,0 0,-84 m 16,24.7 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.3,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
3049 class="st80"
3050 inkscape:connector-curvature="0"
3051 id="R_MTHFD1_1" /><path
3052 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3053 d="m 296,378.11855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z m -9.3,-24.4 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z"
3054 class="st73"
3055 inkscape:label="MTHFD1_1 forward"
3056 inkscape:connector-curvature="0"
3057 id="F_MTHFD1_1" /><text
3058 style="font-size:10px;font-family:Calibri"
3059 id="text823"
3060 class="st17 st18"
3061 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3062 x="309.67828"
3063 y="399.18741">H</text>
3064 <path
3065 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3066 d="m 299.8,398.21855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z m -93.6,36.5 c -6.3,2.3 -6.3,2.3 -6.3,2.3 l 6.5,1.7 -1.7,-1.9 1.5,-2.1 z"
3067 class="st73"
3068 inkscape:connector-curvature="0"
3069 id="B_MTHFD1_1" /><text
3070 style="font-size:15.99982166px;font-family:Calibri-Bold"
3071 id="text826"
3072 class="st15 st16"
3073 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
3074 x="254.19125"
3075 y="282.20911">meTHF</text>
3076 <path
3077 style="fill:none;stroke:#000000;stroke-width:2.29760003"
3078 d="m 277.6,301.91855 c -1.6,-5.3 -17.5,-4.5 -17.5,-4.5 m 2.3,19.7 c 9.8,2.5 15.9,-3.8 15.9,-3.8 m 0.3,11.1 -0.2,-34.2"
3079 class="st79"
3080 inkscape:label="MTHFD2_1 "
3081 inkscape:connector-curvature="0"
3082 id="R_MTHFD2_1" /><path
3083 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3084 d="m 280.6,292.01855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -15.6,3.3 c -7,1.6 -7,1.6 -7,1.6 l 6.9,1.6 -1.7,-1.6 1.8,-1.6 z"
3085 class="st73"
3086 inkscape:label="MTHFD2_1 forward"
3087 inkscape:connector-curvature="0"
3088 id="F_MTHFD2_1" /><path
3089 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3090 d="m 266.3,316.11855 c -7,1.6 -7,1.6 -7,1.6 l 6.9,1.6 -1.7,-1.6 1.8,-1.6 z m 10.5,6.6 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z"
3091 class="st73"
3092 inkscape:label="MTHFD2_1 backward"
3093 inkscape:connector-curvature="0"
3094 id="B_MTHFD2_1" /><rect
3095 style="fill:none;stroke:#231f20;stroke-width:7;stroke-linejoin:round;stroke-miterlimit:2"
3096 height="487.10001"
3097 width="1218.2"
3098 class="st81"
3099 y="682.21857"
3100 x="248.5"
3101 id="rect3188" /><text
3102 style="font-size:10px;font-family:Calibri"
3103 id="text832"
3104 class="st17 st18"
3105 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3106 x="229.13246"
3107 y="320.30942">NADPH</text>
3108 <text
3109 style="font-size:9.99962234px;font-family:Calibri"
3110 id="text834"
3111 class="st17 st18"
3112 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3113 x="229.66826"
3114 y="302.43216">NADP</text>
3115 <text
3116 style="font-size:16.0003109px;font-family:Calibri-Bold"
3117 id="text836"
3118 class="st15 st16"
3119 transform="matrix(0.9999806,0.00622953,-0.00622953,0.9999806,0,0)"
3120 x="748.04932"
3121 y="1068.5068">DHF</text>
3122 <text
3123 style="font-size:15.99927998px;font-family:Calibri-Bold"
3124 id="text838"
3125 class="st15 st16"
3126 transform="matrix(0.99984501,-0.01760548,0.01760548,0.99984501,0,0)"
3127 x="629.1507"
3128 y="1083.5598">Folate</text>
3129 <path
3130 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3131 d="m 730.9,1070.9186 c 7.4,-2 7.4,-2 7.4,-2 l -7.2,-2.3 1.8,2.2 -2,2.1 z m -2.4,-14.1 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
3132 class="st73"
3133 inkscape:label="DHFRL1_DHFR_5 forward"
3134 inkscape:connector-curvature="0"
3135 id="F_DHFRL1_DHFR_5" /><path
3136 style="fill:none;stroke:#000000;stroke-width:2.29760003"
3137 d="m 732.5,1069.2186 -34.2,0 m 8.6,-15.9 c -2.9,9.6 3.1,16 3.1,16 m 11.4,-0.2 c 5.3,-1.4 5.2,-17.3 5.2,-17.3"
3138 class="st79"
3139 inkscape:label="DHFRL1_DHFR_5 "
3140 inkscape:connector-curvature="0"
3141 id="R_DHFRL1_DHFR_5" /><path
3142 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3143 d="m 700.1,1066.9186 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z m 7.6,-9.7 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
3144 class="st73"
3145 inkscape:label="DHFRL1_DHFR_5 backward"
3146 inkscape:connector-curvature="0"
3147 id="B_DHFRL1_DHFR_5" /><text
3148 style="font-size:9.99962521px;font-family:Calibri"
3149 id="text843"
3150 class="st17 st18"
3151 transform="matrix(0.9997375,0.02291141,-0.02291141,0.9997375,0,0)"
3152 x="744.8653"
3153 y="1031.0618">NADP</text>
3154 <text
3155 style="font-size:9.9998436px;font-family:Calibri"
3156 id="text845"
3157 class="st17 st18"
3158 transform="matrix(0.99991568,-0.012986,0.012986,0.99991568,0,0)"
3159 x="662.83777"
3160 y="1056.4205">NADPH+H</text>
3161 <text
3162 style="font-size:16px;font-family:Calibri-Bold"
3163 id="text847"
3164 class="st15 st16"
3165 transform="matrix(0.99999758,-0.00219903,0.00219903,0.99999758,0,0)"
3166 x="825.8905"
3167 y="1075.1088">THF</text>
3168 <path
3169 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3170 d="m 812.4,1070.3186 c 7.3,-2 7.3,-2 7.3,-2 l -7.2,-2.3 1.8,2.2 -1.9,2.1 z m -2.4,-14.1 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
3171 class="st73"
3172 inkscape:label="DHFRL1_DHFR_6 forward"
3173 inkscape:connector-curvature="0"
3174 id="F_DHFRL1_DHFR_6" /><path
3175 style="fill:none;stroke:#000000;stroke-width:2.29760003"
3176 d="m 814,1068.5186 -34.2,0 m 8.6,-15.8 c -2.9,9.6 3.1,16 3.1,16 m 11.4,-0.2 c 5.3,-1.4 5.2,-17.3 5.2,-17.3"
3177 class="st79"
3178 inkscape:label="DHFRL1_DHFR_6 "
3179 inkscape:connector-curvature="0"
3180 id="R_DHFRL1_DHFR_6" /><path
3181 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3182 d="m 781.6,1066.3186 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z m 7.5,-9.7 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
3183 class="st73"
3184 inkscape:label="DHFRL1_DHFR_6 backward"
3185 inkscape:connector-curvature="0"
3186 id="B_DHFRL1_DHFR_6" /><text
3187 style="font-size:10.00011921px;font-family:Calibri"
3188 id="text852"
3189 class="st17 st18"
3190 transform="matrix(0.99998813,0.00487302,-0.00487302,0.99998813,0,0)"
3191 x="809.07843"
3192 y="1042.3011">NADP</text>
3193 <text
3194 style="font-size:10px;font-family:Calibri"
3195 id="text854"
3196 class="st17 st18"
3197 transform="matrix(0.99999791,-0.00204595,0.00204595,0.99999791,0,0)"
3198 x="756.18549"
3199 y="1047.5868">NADPH+H</text>
3200 <text
3201 style="font-size:16.00077438px;font-family:Calibri-Bold"
3202 id="text856"
3203 class="st15 st16"
3204 transform="matrix(0.99995156,0.00984282,-0.00984282,0.99995156,0,0)"
3205 x="919.18933"
3206 y="1061.8497">10-formylTHF</text>
3207 <path
3208 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3209 d="m 895.7,1056.5186 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z m 2.4,14.1 c 7.3,-2 7.3,-2 7.3,-2 l -7.2,-2.3 1.8,2.2 -1.9,2.1 z"
3210 class="st73"
3211 inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297_2 forward"
3212 inkscape:connector-curvature="0"
3213 id="F_MTHFD1_AL445665_1_AQP7P4_LOC286297_2" /><path
3214 style="fill:none;stroke:#000000;stroke-width:2.29760003"
3215 d="m 888.6,1068.8186 c 5.3,-1.4 5.2,-17.3 5.2,-17.3 m -19.7,1.5 c -2.9,9.6 3.1,16 3.1,16 m 22.5,-0.1 -34.2,0"
3216 class="st79"
3217 inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297_2"
3218 inkscape:connector-curvature="0"
3219 id="R_MTHFD1_AL445665_1_AQP7P4_LOC286297_2" /><path
3220 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3221 d="m 875.1,1056.9186 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z m -7.6,9.7 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z"
3222 class="st73"
3223 inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297_2 backward"
3224 inkscape:connector-curvature="0"
3225 id="B_MTHFD1_AL445665_1_AQP7P4_LOC286297_2" /><text
3226 style="font-size:16px;font-family:Calibri-Bold"
3227 id="text861"
3228 class="st15 st16"
3229 transform="matrix(0.9999915,0.00412203,-0.00412203,0.9999915,0,0)"
3230 x="805.01166"
3231 y="1025.8337">mTHF</text>
3232 <path
3233 style="fill:none;stroke:#000000;stroke-width:1.3247"
3234 d="m 900.4,1026.9186 c 5.3,-1.1 5.2,-13.8 5.2,-13.8 m -19.8,1.2 c -3,7.7 3.2,12.8 3.2,12.8 m 44.5,25.3 0.6,-25.4 -84.3,-0.1"
3235 class="st82"
3236 inkscape:connector-curvature="0"
3237 id="R_MTHFD1_2" /><path
3238 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3239 d="m 853.1,1024.7186 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z m 33.5,-9 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
3240 class="st73"
3241 inkscape:connector-curvature="0"
3242 id="F_MTHFD1_2" /><text
3243 style="font-size:10px;font-family:Calibri"
3244 id="text865"
3245 class="st17 st18"
3246 transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
3247 x="876.94342"
3248 y="1005.7078">H</text>
3249 <text
3250 style="font-size:6.09369993px;font-family:Calibri"
3251 id="text867"
3252 class="st17 st26"
3253 transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
3254 x="883.17377"
3255 y="1007.7078">2</text>
3256 <text
3257 style="font-size:10px;font-family:Calibri"
3258 id="text869"
3259 class="st17 st18"
3260 transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
3261 x="886.2627"
3262 y="1005.7078">O</text>
3263 <path
3264 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3265 d="m 931.6,1049.1186 c 2.2,6.3 2.2,6.3 2.2,6.3 l 1.7,-6.5 -1.9,1.7 -2,-1.5 z m -24.1,-33.9 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
3266 class="st73"
3267 inkscape:connector-curvature="0"
3268 id="B_MTHFD1_2" /><text
3269 style="font-size:16.00037193px;font-family:Calibri-Bold"
3270 id="text872"
3271 class="st15 st16"
3272 transform="matrix(0.99997671,0.00682482,-0.00682482,0.99997671,0,0)"
3273 x="707.71307"
3274 y="1025.7979">meTHF</text>
3275 <path
3276 style="fill:none;stroke:#000000;stroke-width:2.29760003"
3277 d="m 791.2,1026.6186 -34.2,0 m 26.8,-15.4 c 2.6,9.7 -3.7,15.9 -3.7,15.9 m -11.3,-0.6 c -5.3,-1.6 -4.6,-17.4 -4.6,-17.4"
3278 class="st79"
3279 inkscape:connector-curvature="0"
3280 id="R_MTHFD2_4" /><path
3281 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3282 d="m 762.1,1013.9186 c 1.5,-7 1.5,-7 1.5,-7 l 1.7,6.9 -1.6,-1.7 -1.6,1.8 z m -3.3,10.5 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z"
3283 class="st73"
3284 inkscape:connector-curvature="0"
3285 id="F_MTHFD2_4" /><path
3286 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3287 d="m 789.6,1028.4186 c 7.3,-2 7.3,-2 7.3,-2 l -7.2,-2.3 1.8,2.2 -1.9,2.1 z m -6.7,-13.3 c 1.5,-7 1.5,-7 1.5,-7 l 1.7,6.9 -1.6,-1.7 -1.6,1.8 z"
3288 class="st73"
3289 inkscape:connector-curvature="0"
3290 id="B_MTHFD2_4" /><text
3291 style="font-size:10px;font-family:Calibri"
3292 id="text877"
3293 class="st17 st18"
3294 transform="matrix(0.99989917,0.01420008,-0.01420008,0.99989917,0,0)"
3295 x="790.88013"
3296 y="994.28802">NADPH</text>
3297 <text
3298 style="font-size:10px;font-family:Calibri"
3299 id="text879"
3300 class="st17 st18"
3301 transform="matrix(0.99990781,0.01357832,-0.01357832,0.99990781,0,0)"
3302 x="760.42932"
3303 y="995.04498">NADP</text>
3304 <text
3305 style="font-size:16px;font-family:Calibri-Bold"
3306 id="text881"
3307 class="st15 st16"
3308 x="315.19269"
3309 y="786.4632">OAA</text>
3310 <text
3311 style="font-size:16px;font-family:Calibri-Bold"
3312 id="text883"
3313 class="st15 st16"
3314 x="942.22101"
3315 y="658.15649">Gln</text>
3316 <text
3317 style="font-size:16px;font-family:Calibri-Bold"
3318 id="text885"
3319 class="st15 st16"
3320 x="1033.4213"
3321 y="658.15649">Glu</text>
3322 <path
3323 style="fill:none;stroke:#000000;stroke-width:1.56400001"
3324 d="m 969.4,653.91855 53.9,0 m -19.5,0.5 c 4.6,-0.4 6.2,-11.9 6.2,-11.9 m -5.5,11.7 c -4.5,0.5 -6.6,11.7 -6.6,11.7"
3325 class="st83"
3326 inkscape:label="GLS2"
3327 inkscape:connector-curvature="0"
3328 id="R_GLS2" /><text
3329 style="font-size:10px;font-family:Calibri"
3330 id="text888"
3331 class="st17 st18"
3332 x="1000.8987"
3333 y="636.82635">NH</text>
3334 <text
3335 style="font-size:6.09369993px;font-family:Calibri"
3336 id="text890"
3337 class="st17 st26"
3338 x="1013.5844"
3339 y="638.82635">3</text>
3340 <text
3341 style="font-size:10px;font-family:Calibri"
3342 id="text892"
3343 class="st17 st18"
3344 x="983.43292"
3345 y="674.4173">H</text>
3346 <text
3347 style="font-size:6.09369993px;font-family:Calibri"
3348 id="text894"
3349 class="st17 st26"
3350 x="989.66345"
3351 y="676.4173">2</text>
3352 <text
3353 style="font-size:10px;font-family:Calibri"
3354 id="text896"
3355 class="st17 st18"
3356 x="992.7522"
3357 y="674.4173">O</text>
3358 <text
3359 style="font-size:10px;font-family:Calibri"
3360 id="text898"
3361 class="st17 st18"
3362 x="1035.5336"
3363 y="601.31757">ATP</text>
3364 <text
3365 style="font-size:10px;font-family:Calibri"
3366 id="text900"
3367 class="st17 st18"
3368 x="1022.9135"
3369 y="638.01587">ADP</text>
3370 <text
3371 style="font-size:10px;font-family:Calibri"
3372 id="text902"
3373 class="st17 st18"
3374 x="989.93292"
3375 y="602.9173">NH</text>
3376 <text
3377 style="font-size:6.09369993px;font-family:Calibri"
3378 id="text904"
3379 class="st17 st26"
3380 x="1002.6184"
3381 y="604.9173">3</text>
3382 <text
3383 style="font-size:10px;font-family:Calibri"
3384 id="text906"
3385 class="st17 st18"
3386 x="980.08435"
3387 y="638.513">Pi</text>
3388 <path
3389 style="fill:none;stroke:#000000;stroke-width:2.11560011"
3390 d="m 1050.4,645.51855 0,-29.9 -92.5,0 0,24 m 78.9,-24.4 c 5,-1.2 4.3,-13.1 4.3,-13.1 m -4.2,12.8 c -5.2,1 -5.3,9.2 -5.3,9.2 m -44,-8.8 c -3.7,0.9 -3.8,9 -3.8,9 m 11,-8.5 c 5,-1.1 4.3,-12 4.3,-12"
3391 class="st84"
3392 inkscape:label="#R_gln_synthetase"
3393 inkscape:connector-curvature="0"
3394 id="R_GS" /><path
3395 style="fill:none;stroke:#000000;stroke-width:1.39260006"
3396 d="m 956.3,660.51855 0,32.4 m 0.4,-9.9 c -2.6,2.5 9.5,6.9 9.5,6.9 m -10,-12.7 c 0.4,-4.4 -9.3,-7.5 -9.3,-7.5"
3397 class="st85"
3398 inkscape:label="TransportGln"
3399 inkscape:connector-curvature="0"
3400 id="R_TransportGln" /><path
3401 style="fill:none;stroke:#000000;stroke-width:1.12300003"
3402 d="m 1052,660.31855 0,32.2 m 0.1,-12.3 c 0.1,5.1 9.8,8.5 9.8,8.5 m -9.9,-9.3 c 0.2,-4.1 -8.4,-8.3 -8.4,-8.3"
3403 class="st86"
3404 inkscape:label="TransportGlu"
3405 inkscape:connector-curvature="0"
3406 id="R_TransportGlu" /><text
3407 style="font-size:9.87795448px;font-family:Calibri"
3408 id="text911"
3409 class="st17 st87"
3410 transform="scale(1.0123241,0.98782595)"
3411 x="926.31677"
3412 y="681.64825">H</text>
3413 <text
3414 style="font-size:9.87795448px;font-family:Calibri"
3415 id="text913"
3416 class="st17 st87"
3417 transform="scale(1.0123241,0.98782595)"
3418 x="962.82196"
3419 y="702.19128">H</text>
3420 <text
3421 style="font-size:10px;font-family:Calibri"
3422 id="text915"
3423 class="st17 st18"
3424 x="1032.5765"
3425 y="674.64575">H</text>
3426 <text
3427 style="font-size:10px;font-family:Calibri"
3428 id="text917"
3429 class="st17 st18"
3430 x="1070.2865"
3431 y="694.58521">H</text>
3432 <text
3433 style="font-size:15.80470657px;font-family:Calibri-Bold"
3434 id="text919"
3435 class="st15 st88"
3436 transform="scale(1.0123241,0.98782595)"
3437 x="932.36621"
3438 y="721.383">Gln</text>
3439 <text
3440 style="font-size:16px;font-family:Calibri-Bold"
3441 id="text921"
3442 class="st15 st16"
3443 x="1040.6478"
3444 y="712.59686">Glu</text>
3445 <path
3446 style="fill:none;stroke:#000000;stroke-width:2.09260011"
3447 d="m 969.6,707.11855 63.5,0 m -30.7,0.2 c 5.9,-0.2 7.8,-7.5 7.8,-7.5 m -12.1,7.6 c -4.6,-0.4 -6.8,-9.9 -6.8,-9.9"
3448 class="st89"
3449 inkscape:connector-curvature="0"
3450 id="R_GLS" /><text
3451 style="font-size:10px;font-family:Calibri"
3452 id="text924"
3453 class="st17 st18"
3454 x="1006.3949"
3455 y="693.48657">NH</text>
3456 <text
3457 style="font-size:6.09369993px;font-family:Calibri"
3458 id="text926"
3459 class="st17 st26"
3460 x="1019.0804"
3461 y="695.48657">3</text>
3462 <text
3463 style="font-size:10px;font-family:Calibri"
3464 id="text928"
3465 class="st17 st18"
3466 x="982.98663"
3467 y="694.27856">H</text>
3468 <text
3469 style="font-size:6.09369993px;font-family:Calibri"
3470 id="text930"
3471 class="st17 st26"
3472 x="989.2171"
3473 y="696.27856">2</text>
3474 <text
3475 style="font-size:10px;font-family:Calibri"
3476 id="text932"
3477 class="st17 st18"
3478 x="992.30591"
3479 y="694.27856">O</text>
3480 <text
3481 style="font-size:16.00031662px;font-family:Calibri-Bold"
3482 id="text934"
3483 class="st15 st16"
3484 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3485 x="1331.6912"
3486 y="771.82178">NH</text>
3487 <text
3488 style="font-size:9.7501936px;font-family:Calibri-Bold"
3489 id="text936"
3490 class="st15 st40"
3491 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3492 x="1352.3239"
3493 y="775.02191">3</text>
3494 <path
3495 style="fill:none;stroke:#000000;stroke-width:1.76709998"
3496 d="m 1189,777.11855 0.5,-30.4 m 10.5,7.1 c -8.9,1.1 -11.1,9.1 -11.1,9.1 m 0.2,-0.1 c -0.5,5.2 10.5,8.6 10.5,8.6"
3497 class="st90"
3498 inkscape:connector-curvature="0"
3499 id="R_OTC_LEFTY1" /><text
3500 style="font-size:16.00031662px;font-family:Calibri-Bold"
3501 id="text939"
3502 class="st15 st16"
3503 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3504 x="1180.2643"
3505 y="782.81091">Orn</text>
3506 <text
3507 style="font-size:16.00031662px;font-family:Calibri-Bold"
3508 id="text941"
3509 class="st15 st16"
3510 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3511 x="1187.484"
3512 y="728.58057">Ci</text>
3513 <text
3514 style="font-size:16.00031662px;font-family:Calibri-Bold"
3515 id="text943"
3516 class="st15 st16"
3517 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3518 x="1187.3484"
3519 y="635.12445">Ci</text>
3520 <text
3521 style="font-size:16.00031662px;font-family:Calibri-Bold"
3522 id="text945"
3523 class="st15 st16"
3524 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3525 x="1153.5397"
3526 y="588.43402">ArgSuc</text>
3527 <text
3528 style="font-size:16.00031662px;font-family:Calibri-Bold"
3529 id="text947"
3530 class="st15 st16"
3531 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3532 x="1223.7125"
3533 y="571.21527">Arg</text>
3534 <text
3535 style="font-size:16.00031662px;font-family:Calibri-Bold"
3536 id="text949"
3537 class="st15 st16"
3538 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3539 x="1230.6833"
3540 y="630.91748">Orn</text>
3541 <text
3542 style="font-size:10px;font-family:Calibri"
3543 id="text951"
3544 class="st17 st18"
3545 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3546 x="1132.3175"
3547 y="625.07318">Asp</text>
3548 <text
3549 style="font-size:10px;font-family:Calibri"
3550 id="text953"
3551 class="st17 st18"
3552 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3553 x="1147.2687"
3554 y="625.07312">+</text>
3555 <text
3556 style="font-size:10px;font-family:Calibri"
3557 id="text955"
3558 class="st17 st18"
3559 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
3560 x="1152.249"
3561 y="625.07312">ATP</text>
3562 <text
3563 style="font-size:9.99962234px;font-family:Calibri"
3564 id="text957"
3565 class="st17 st18"
3566 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3567 x="1113.4318"
3568 y="629.14063">AMP</text>
3569 <text
3570 style="font-size:9.99962234px;font-family:Calibri"
3571 id="text959"
3572 class="st17 st18"
3573 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3574 x="1132.9337"
3575 y="629.1405">+</text>
3576 <text
3577 style="font-size:9.99962234px;font-family:Calibri"
3578 id="text961"
3579 class="st17 st18"
3580 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3581 x="1137.9142"
3582 y="629.14056">PPi</text>
3583 <path
3584 style="fill:none;stroke:#000000;stroke-width:2.0948"
3585 d="m 1179.6,616.11855 c -2.6,-4.9 -15,-1.2 -15,-1.2 m 1.5,11.8 c 10.1,0.2 14.5,-7.4 14.5,-7.4 m -1.1,-15.4 c -3,15.1 4.9,26.9 4.9,26.9"
3586 class="st76"
3587 inkscape:label="ASS1 "
3588 inkscape:connector-curvature="0"
3589 id="R_ASS1" /><text
3590 style="font-size:10.00030041px;font-family:Calibri"
3591 id="text964"
3592 class="st17 st18"
3593 transform="matrix(0.99427012,-0.10689679,0.10689679,0.99427012,0,0)"
3594 x="1114.6914"
3595 y="680.83099">Fum</text>
3596 <path
3597 style="fill:none;stroke:#000000;stroke-width:1.79009998"
3598 d="m 1214.6,571.01855 c -16.6,-3.2 -28.6,8.8 -28.6,8.8 m 7.5,-5.6 c 5.9,-1.9 4.1,-12.3 4.1,-12.3"
3599 class="st91"
3600 inkscape:connector-curvature="0"
3601 id="R_ASL_CRCP" /><path
3602 style="fill:none;stroke:#000000;stroke-width:1.92120004"
3603 d="m 1248.2,621.11855 c 4.6,-20.3 -6.2,-36.5 -6.2,-36.5 m 18.6,3.2 c -9,-1.2 -13.6,6 -13.6,6 m 0.3,3.6 c 2,3.5 14.6,1.8 14.6,1.8"
3604 class="st92"
3605 inkscape:connector-curvature="0"
3606 id="R_ARG2_ARG1" /><text
3607 style="font-size:9.99962234px;font-family:Calibri"
3608 id="text968"
3609 class="st17 st18"
3610 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3611 x="1254.6495"
3612 y="601.48828">H</text>
3613 <text
3614 style="font-size:6.09346962px;font-family:Calibri"
3615 id="text970"
3616 class="st17 st26"
3617 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3618 x="1260.88"
3619 y="603.48834">2</text>
3620 <text
3621 style="font-size:9.99962234px;font-family:Calibri"
3622 id="text972"
3623 class="st17 st18"
3624 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3625 x="1263.9689"
3626 y="601.48822">O</text>
3627 <text
3628 style="font-size:9.99962234px;font-family:Calibri"
3629 id="text974"
3630 class="st17 st18"
3631 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3632 x="1262.8811"
3633 y="616.68073">Urea</text>
3634 <path
3635 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3636 d="m 1186.7,576.11855 c -4.8,5.9 -4.8,5.9 -4.8,5.9 l 7.2,-2.4 -2.7,-0.7 0.3,-2.8 z"
3637 class="st73"
3638 inkscape:label="ASL_CRCP backward"
3639 inkscape:connector-curvature="0"
3640 id="B_ASL_CRCP" /><path
3641 style="fill:none;stroke:#000000;stroke-width:1.3319"
3642 d="m 1199,562.51855 c -1.6,-4.9 -1.6,-4.9 -1.6,-4.9 l -1,4.9 1.2,-1.2 1.4,1.2 z m 11.8,10.5 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.1 1.8,2.1 -1.8,2.2 z"
3643 class="st93"
3644 inkscape:label="ASL_CRCP forward"
3645 inkscape:connector-curvature="0"
3646 id="F_ASL_CRCP" /><path
3647 style="fill:none;stroke:#000000;stroke-width:2.13980007"
3648 d="m 1190.5,651.51855 0.1,71.7 m -0.3,-53.8 c 2.4,5.4 15.3,4 15.3,4 m -15.4,-12.9 c 2.4,5.4 15.3,4 15.3,4 m -14.9,35.9 c 1.9,-5.6 15,-5.4 15,-5.4 m -14.6,17.1 c 1.9,-5.6 15,-5.4 15,-5.4"
3649 class="st94"
3650 inkscape:label="SLC25A15_SLC25A2_1"
3651 inkscape:connector-curvature="0"
3652 id="R_SLC25A15_SLC25A2_1" /><text
3653 style="font-size:14px;font-family:Calibri-Bold"
3654 id="text979"
3655 class="st15 st38"
3656 transform="matrix(0.99980805,-0.01959226,0.01959226,0.99980805,0,0)"
3657 x="1201.152"
3658 y="721.48889">H</text>
3659 <text
3660 style="font-size:13.99942493px;font-family:Calibri-Bold"
3661 id="text981"
3662 class="st15 st38"
3663 transform="matrix(0.99984109,-0.01782667,0.01782667,0.99984109,0,0)"
3664 x="1201.3977"
3665 y="733.09906">Orn</text>
3666 <text
3667 style="font-size:16.00031662px;font-family:Calibri-Bold"
3668 id="text983"
3669 class="st15 st16"
3670 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
3671 x="1287.2751"
3672 y="577.22217">Putr</text>
3673 <path
3674 style="fill:none;stroke:#000000;stroke-width:1.36409998"
3675 d="m 1256.3,636.01855 41.1,0 0,-40.3 m 10.7,7.5 c -6.7,-1.2 -10.2,6.1 -10.2,6.1"
3676 class="st95"
3677 inkscape:connector-curvature="0"
3678 id="R_OGDH_ODC1_OGDHL" /><text
3679 style="font-size:9.99962234px;font-family:Calibri"
3680 id="text986"
3681 class="st17 st18"
3682 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3683 x="1308.797"
3684 y="620.35846">CO</text>
3685 <text
3686 style="font-size:6.09346962px;font-family:Calibri"
3687 id="text988"
3688 class="st17 st26"
3689 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3690 x="1320.6622"
3691 y="622.35846">2</text>
3692 <text
3693 style="font-size:16px;font-family:Calibri-Bold"
3694 id="text990"
3695 class="st15 st16"
3696 x="1340.1732"
3697 y="712.76776">GluSA</text>
3698 <text
3699 style="font-size:10px;font-family:Calibri"
3700 id="text992"
3701 class="st17 st18"
3702 x="1268.7523"
3703 y="692.13495">AKG</text>
3704 <text
3705 style="font-size:10px;font-family:Calibri"
3706 id="text994"
3707 class="st17 st18"
3708 x="1299.0814"
3709 y="692.05975">Glu</text>
3710 <path
3711 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3712 d="m 1306.2,700.71855 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.7,6.9 1.6,-1.7 1.5,1.8 z m 21.3,8.8 c 6.3,-2.2 6.3,-2.2 6.3,-2.2 l -6.5,-1.7 1.7,1.9 -1.5,2 z"
3713 class="st73"
3714 inkscape:connector-curvature="0"
3715 id="F_OAT" /><path
3716 style="fill:none;stroke:#000000;stroke-width:2.21600008"
3717 d="m 1239.8,707.61855 88.2,0.1 m -28.6,-0.2 c 5.4,-0.7 4.9,-7.6 4.9,-7.6 m -21.6,-4.9 c -1.9,7.9 4.4,12.5 4.4,12.5"
3718 class="st96"
3719 inkscape:connector-curvature="0"
3720 id="R_OAT" /><path
3721 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3722 d="m 1359,688.51855 c 2.3,6.3 2.3,6.3 2.3,6.3 l 1.7,-6.5 -1.9,1.7 -2.1,-1.5 z"
3723 class="st73"
3724 inkscape:label="Transport_Lglu5semialdehyde backward"
3725 inkscape:connector-curvature="0"
3726 id="B_Transport_Lglu5semialdehyde" /><path
3727 style="fill:none;stroke:#000000;stroke-width:2.34100008"
3728 d="m 1361,668.81855 0.2,20"
3729 class="st97"
3730 inkscape:label="Transport_Lglu5semialdehyde "
3731 inkscape:connector-curvature="0"
3732 id="R_Transport_Lglu5semialdehyde" /><path
3733 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3734 d="m 1362.8,670.21855 c -0.7,-2.4 -1.3,-4.9 -2,-7.3 -0.8,2.4 -1.5,4.8 -2.3,7.3 0.7,-0.6 1.5,-1.2 2.2,-1.8 0.7,0.6 1.4,1.2 2.1,1.8 z"
3735 class="st73"
3736 inkscape:label="Transport_Lglu5semialdehyde forward"
3737 inkscape:connector-curvature="0"
3738 id="F_Transport_Lglu5semialdehyde" /><text
3739 style="font-size:16px;font-family:Calibri-Bold"
3740 id="text1001"
3741 class="st15 st16"
3742 x="1336.557"
3743 y="658.23456">GluSA</text>
3744 <path
3745 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3746 d="m 1358.4,637.01855 c 2,6.4 2,6.4 2,6.4 l 1.9,-6.4 -1.9,1.6 -2,-1.6 z"
3747 class="st73"
3748 inkscape:label="ALDH4A1_2 backward"
3749 inkscape:connector-curvature="0"
3750 id="B_ALDH4A1_2" /><text
3751 style="font-size:16px;font-family:Calibri-Bold"
3752 id="text1004"
3753 class="st15 st16"
3754 x="1352.6332"
3755 y="608.19745">P5C</text>
3756 <path
3757 style="fill:none;stroke:#000000;stroke-width:1.24119997"
3758 d="m 1360.4,618.41855 0.1,20.4 m 0.1,-8.4 c -3,-6.6 -10.4,-6.2 -10.4,-6.2"
3759 class="st98"
3760 inkscape:connector-curvature="0"
3761 id="R_ALDH4A1_2" /><text
3762 style="font-size:9.99962234px;font-family:Calibri"
3763 id="text1007"
3764 class="st17 st18"
3765 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3766 x="1319.298"
3767 y="638.0332">H</text>
3768 <text
3769 style="font-size:6.09346962px;font-family:Calibri"
3770 id="text1009"
3771 class="st17 st26"
3772 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3773 x="1325.5284"
3774 y="640.03333">2</text>
3775 <text
3776 style="font-size:9.99962234px;font-family:Calibri"
3777 id="text1011"
3778 class="st17 st18"
3779 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
3780 x="1328.6173"
3781 y="638.03326">O</text>
3782 <text
3783 style="font-size:10px;font-family:Calibri"
3784 id="text1013"
3785 class="st17 st18"
3786 transform="matrix(0.99990761,-0.01359275,0.01359275,0.99990761,0,0)"
3787 x="1371.2954"
3788 y="643.84912">NADH+H</text>
3789 <text
3790 style="font-size:10px;font-family:Calibri"
3791 id="text1015"
3792 class="st17 st18"
3793 transform="matrix(0.99939509,-0.03477735,0.03477735,0.99939509,0,0)"
3794 x="1397.1116"
3795 y="673.6972">NAD</text>
3796 <text
3797 style="font-size:16px;font-family:Calibri-Bold"
3798 id="text1017"
3799 class="st15 st16"
3800 x="1442.0248"
3801 y="606.54315">Pro</text>
3802 <text
3803 style="font-size:10.00029469px;font-family:Calibri"
3804 id="text1019"
3805 class="st17 st18"
3806 transform="matrix(0.99987054,0.01609049,-0.01609049,0.99987054,0,0)"
3807 x="1389.0287"
3808 y="630.53644">NADPH+H</text>
3809 <text
3810 style="font-size:9.99974251px;font-family:Calibri"
3811 id="text1021"
3812 class="st17 st18"
3813 transform="matrix(0.99922571,-0.03934428,0.03934428,0.99922571,0,0)"
3814 x="1378.6187"
3815 y="707.83429">NADP</text>
3816 <text
3817 style="font-size:9.99983883px;font-family:Calibri"
3818 id="text1023"
3819 class="st17 st18"
3820 transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
3821 x="1286.8578"
3822 y="776.54065">NADH</text>
3823 <text
3824 style="font-size:9.99983883px;font-family:Calibri"
3825 id="text1025"
3826 class="st17 st18"
3827 transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
3828 x="1311.4819"
3829 y="776.54071">+</text>
3830 <text
3831 style="font-size:9.99983883px;font-family:Calibri"
3832 id="text1027"
3833 class="st17 st18"
3834 transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
3835 x="1316.4624"
3836 y="776.54065">H</text>
3837 <text
3838 style="font-size:10px;font-family:Calibri"
3839 id="text1029"
3840 class="st17 st18"
3841 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3842 x="1303.4719"
3843 y="727.08441">NAD+H</text>
3844 <text
3845 style="font-size:6.09369993px;font-family:Calibri"
3846 id="text1031"
3847 class="st17 st26"
3848 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3849 x="1333.0753"
3850 y="729.08441">2</text>
3851 <text
3852 style="font-size:10px;font-family:Calibri"
3853 id="text1033"
3854 class="st17 st18"
3855 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3856 x="1336.1642"
3857 y="727.08441">O</text>
3858 <path
3859 style="fill:none;stroke:#000000;stroke-width:1.78269994"
3860 d="m 1360.8,720.31855 0.3,32.5 m -0.2,-19.6 c -1.4,-5 -10.8,-3.5 -10.8,-3.5 m 0.6,11.6 c 7.1,2 10.7,-4.9 10.7,-4.9"
3861 class="st99"
3862 inkscape:connector-curvature="0"
3863 id="R_ALDH4A1_1" /><text
3864 style="font-size:16px;font-family:Calibri-Bold"
3865 id="text1036"
3866 class="st15 st16"
3867 x="1350.3373"
3868 y="771.66528">Glu</text>
3869 <path
3870 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3871 d="m 1358.9,750.41855 c 2.3,6.3 2.3,6.3 2.3,6.3 l 1.7,-6.5 -1.9,1.7 -2.1,-1.5 z m -6.9,-10.7 c -7.1,0.9 -7.1,0.9 -7.1,0.9 l 6.8,2.3 -1.6,-1.8 1.9,-1.4 z"
3872 class="st73"
3873 inkscape:connector-curvature="0"
3874 id="B_ALDH4A1_1" /><path
3875 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3876 d="m 1351,728.11855 c -6.9,1.7 -6.9,1.7 -6.9,1.7 l 7,1.5 -1.8,-1.6 1.7,-1.6 z m 11.8,-3.7 c -0.7,-2.4 -1.3,-4.9 -2,-7.3 -0.8,2.4 -1.5,4.8 -2.3,7.3 0.7,-0.6 1.5,-1.2 2.2,-1.8 0.7,0.5 1.4,1.2 2.1,1.8 z"
3877 class="st73"
3878 inkscape:connector-curvature="0"
3879 id="F_ALDH4A1_1" /><text
3880 style="font-size:10px;font-family:Calibri"
3881 id="text1040"
3882 class="st17 st18"
3883 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3884 x="888.26978"
3885 y="706.72406">NAD</text>
3886 <text
3887 style="font-size:10px;font-family:Calibri"
3888 id="text1042"
3889 class="st17 st18"
3890 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3891 x="906.66333"
3892 y="706.72406">+</text>
3893 <text
3894 style="font-size:10px;font-family:Calibri"
3895 id="text1044"
3896 class="st17 st18"
3897 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3898 x="888.2688"
3899 y="719.22406">H</text>
3900 <text
3901 style="font-size:6.09369993px;font-family:Calibri"
3902 id="text1046"
3903 class="st17 st26"
3904 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3905 x="894.50018"
3906 y="721.22406">2</text>
3907 <text
3908 style="font-size:10px;font-family:Calibri"
3909 id="text1048"
3910 class="st17 st18"
3911 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3912 x="897.58905"
3913 y="719.224">O</text>
3914 <text
3915 style="font-size:9.99983883px;font-family:Calibri"
3916 id="text1050"
3917 class="st17 st18"
3918 transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
3919 x="824.83246"
3920 y="730.75824">NADH+</text>
3921 <text
3922 style="font-size:9.99983883px;font-family:Calibri"
3923 id="text1052"
3924 class="st17 st18"
3925 transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
3926 x="824.83344"
3927 y="743.2583">H+NH</text>
3928 <text
3929 style="font-size:6.0936017px;font-family:Calibri"
3930 id="text1054"
3931 class="st17 st26"
3932 transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
3933 x="848.72894"
3934 y="745.25824">3</text>
3935 <path
3936 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3937 d="m 935,761.21855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.7 -1.6,-1.6 z m -171.9,-16.2 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
3938 class="st73"
3939 inkscape:connector-curvature="0"
3940 id="B_GLUD1_GLUD2_2" /><path
3941 style="fill:none;stroke:#000000;stroke-width:1.86580002"
3942 d="m 941.8,747.41855 c -6.2,1.5 -5.1,14.4 -5.1,14.4 m 21.3,0.1 c 2.7,-9 -4.9,-14.5 -4.9,-14.5 m 103.9,-26.4 c 0,26.3 0,26.3 0,26.3 l -295.7,0"
3943 class="st100"
3944 inkscape:connector-curvature="0"
3945 id="R_GLUD1_GLUD2_2" /><path
3946 style="fill:none;stroke:#000000;stroke-width:2.09949994"
3947 d="m 1059,725.01855 c -2.3,-7.3 -2.3,-7.3 -2.3,-7.3 l -2.1,7.3 2.1,-1.9 2.3,1.9 z m -102.6,36.5 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.7 -1.6,-1.6 z"
3948 class="st73"
3949 inkscape:connector-curvature="0"
3950 id="F_GLUD1_GLUD2_2" /><text
3951 style="font-size:10px;font-family:Calibri"
3952 id="text1059"
3953 class="st17 st18"
3954 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3955 x="956.75903"
3956 y="773.34814">NADP</text>
3957 <text
3958 style="font-size:10px;font-family:Calibri"
3959 id="text1061"
3960 class="st17 st18"
3961 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3962 x="980.31866"
3963 y="773.34814">+</text>
3964 <text
3965 style="font-size:10px;font-family:Calibri"
3966 id="text1063"
3967 class="st17 st18"
3968 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3969 x="956.75903"
3970 y="785.84802">H</text>
3971 <text
3972 style="font-size:6.09369993px;font-family:Calibri"
3973 id="text1065"
3974 class="st17 st26"
3975 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3976 x="962.9895"
3977 y="787.84808">2</text>
3978 <text
3979 style="font-size:10px;font-family:Calibri"
3980 id="text1067"
3981 class="st17 st18"
3982 transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
3983 x="966.07831"
3984 y="785.84814">O</text>
3985 <text
3986 style="font-size:9.99983883px;font-family:Calibri"
3987 id="text1069"
3988 class="st17 st18"
3989 transform="matrix(0.99971611,-0.02382646,0.02382646,0.99971611,0,0)"
3990 x="892.81866"
3991 y="799.80231">NADPH+</text>
3992 <text
3993 style="font-size:9.99983883px;font-family:Calibri"
3994 id="text1071"
3995 class="st17 st18"
3996 transform="matrix(0.99971611,-0.02382646,0.02382646,0.99971611,0,0)"
3997 x="892.81866"
3998 y="812.30237">H+NH</text>
3999 <text
4000 style="font-size:6.0936017px;font-family:Calibri"
4001 id="text1073"
4002 class="st17 st26"
4003 transform="matrix(0.99971611,-0.02382646,0.02382646,0.99971611,0,0)"
4004 x="916.71509"
4005 y="814.30231">3</text>
4006 <text
4007 style="font-size:15.99982166px;font-family:Calibri-Bold"
4008 id="text1075"
4009 class="st15 st16"
4010 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
4011 x="610.36102"
4012 y="1009.088">Ser</text>
4013 <text
4014 style="font-size:15.99982166px;font-family:Calibri-Bold"
4015 id="text1077"
4016 class="st15 st16"
4017 transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
4018 x="714.42944"
4019 y="1011.3351">Gly</text>
4020 <text
4021 style="font-size:10px;font-family:Calibri"
4022 id="text1079"
4023 class="st17 st18"
4024 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
4025 x="652.00781"
4026 y="1022.0663">THF</text>
4027 <path
4028 style="fill:none;stroke:#000000;stroke-width:2.09949994"
4029 d="m 660.6,1009.4186 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z m -2.4,-14.10005 c -7.3,2 -7.3,2 -7.3,2 l 7.3,2.3 -1.8,-2.2 1.8,-2.1 z"
4030 class="st73"
4031 inkscape:label="SHMT1_2 backward"
4032 inkscape:connector-curvature="0"
4033 id="B_SHMT1_2" /><text
4034 style="font-size:16px;font-family:Calibri-Bold"
4035 id="text1082"
4036 class="st15 st16"
4037 x="316.81769"
4038 y="625.53351">Asp</text>
4039 <text
4040 style="font-size:16px;font-family:Calibri-Bold"
4041 id="text1084"
4042 class="st15 st16"
4043 x="317.24249"
4044 y="728.39868">Asp</text>
4045 <text
4046 style="font-size:16px;font-family:Calibri-Bold"
4047 id="text1086"
4048 class="st15 st16"
4049 x="301.33231"
4050 y="669.98846">H</text>
4051 <text
4052 style="font-size:16px;font-family:Calibri-Bold"
4053 id="text1088"
4054 class="st15 st16"
4055 x="289.33328"
4056 y="654.96118">Glu</text>
4057 <text
4058 style="font-size:16px;font-family:Calibri-Bold"
4059 id="text1090"
4060 class="st15 st16"
4061 x="359.73318"
4062 y="710.5979">H</text>
4063 <text
4064 style="font-size:16px;font-family:Calibri-Bold"
4065 id="text1092"
4066 class="st15 st16"
4067 x="356.95441"
4068 y="697.87531">Glu</text>
4069 <path
4070 style="fill:none;stroke:#000000;stroke-width:2.82299995"
4071 d="m 330.6,717.91855 0.2,-81.5 m 0,65.8 c 1.9,5.9 17.6,4.4 17.6,4.4 m -34.6,-41.3 c 5,-3.9 17.8,4.8 17.8,4.8 m -17.9,-17.1 c 4.7,-4.2 18.1,3.8 18.1,3.8 m -1,32.6 c 1.9,5.9 17.6,4.4 17.6,4.4"
4072 class="st45"
4073 inkscape:label="SLC25A13_SLC25A12"
4074 inkscape:connector-curvature="0"
4075 id="R_SLC25A13_SLC25A12" /><path
4076 style="fill:none;stroke:#000000;stroke-width:2.82299995"
4077 d="m 345.2,696.41855 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.1 1.8,2.1 -1.8,2.2 z m -12.3,-57.1 c -2.3,-7.2 -2.3,-7.2 -2.3,-7.2 l -2,7.3 2.1,-1.9 2.2,1.8 z m 13.2,69.9 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.1 1.8,2.1 -1.8,2.2 z"
4078 class="st45"
4079 inkscape:label="#SLC25A13_SLC25A12"
4080 inkscape:connector-curvature="0"
4081 id="F_SLC25A13_SLC25A12" /><path
4082 style="fill:none;stroke:#000000;stroke-width:2.49320006"
4083 d="m 1491.4,754.31855 -49,-0.2"
4084 class="st101"
4085 inkscape:label="Transport_serine "
4086 inkscape:connector-curvature="0"
4087 id="R_Transport_serine" /><path
4088 style="fill:none;stroke:#000000;stroke-width:2.5"
4089 d="m 1443.1,752.01855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
4090 class="st22"
4091 inkscape:label="Transport_serine f"
4092 inkscape:connector-curvature="0"
4093 id="F_Transport_serine" /><text
4094 style="font-size:16px;font-family:Calibri-Bold"
4095 id="text1098"
4096 class="st15 st16"
4097 x="1409.9398"
4098 y="758.43781">Ser</text>
4099 <text
4100 style="font-size:16px;font-family:Calibri-Bold"
4101 id="text1100"
4102 class="st15 st16"
4103 x="1501.6996"
4104 y="758.50806">Ser</text>
4105 <path
4106 style="fill:none;stroke:#000000;stroke-width:2.48900008"
4107 d="m 1490.5,773.81855 -48.1,-0.2"
4108 class="st102"
4109 inkscape:label="Transport_glycine "
4110 inkscape:connector-curvature="0"
4111 id="R_Transport_glycine" /><path
4112 style="fill:none;stroke:#000000;stroke-width:2.5"
4113 d="m 1443.1,771.51855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
4114 class="st22"
4115 inkscape:label="Transport_glycine backward"
4116 inkscape:connector-curvature="0"
4117 id="B_Transport_glycine" /><path
4118 style="fill:none;stroke:#000000;stroke-width:2.5"
4119 d="m 1489.9,775.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
4120 class="st22"
4121 inkscape:transform-center-y="-3.0492074"
4122 inkscape:transform-center-x="0.87100132"
4123 inkscape:label="Transport_glycine forward"
4124 inkscape:connector-curvature="0"
4125 id="F_Transport_glycine" /><text
4126 style="font-size:16px;font-family:Calibri-Bold"
4127 id="text1105"
4128 class="st15 st16"
4129 x="1408.141"
4130 y="776.79517">Gly</text>
4131 <text
4132 style="font-size:16px;font-family:Calibri-Bold"
4133 id="text1107"
4134 class="st15 st16"
4135 x="1502.0004"
4136 y="777.33026">Gly</text>
4137 <path
4138 style="fill:none;stroke:#000000;stroke-width:2.51880002"
4139 d="m 1497,792.51855 -55.2,-0.2"
4140 class="st103"
4141 inkscape:label="TransportFolate"
4142 inkscape:connector-curvature="0"
4143 id="R_TransportFolate" /><path
4144 style="fill:none;stroke:#000000;stroke-width:2.5"
4145 d="m 1442.5,790.21855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
4146 class="st22"
4147 inkscape:label="TransportFolate f"
4148 inkscape:connector-curvature="0"
4149 id="F_TransportFolate" /><text
4150 style="font-size:16px;font-family:Calibri-Bold"
4151 id="text1111"
4152 class="st15 st16"
4153 x="1386.1674"
4154 y="797.35956">Folate</text>
4155 <text
4156 style="font-size:16px;font-family:Calibri-Bold"
4157 id="text1113"
4158 class="st15 st16"
4159 x="1501.8568"
4160 y="795.38885">Folate</text>
4161 <path
4162 style="fill:none;stroke:#000000;stroke-width:2.49620008"
4163 d="m 1491.2,812.71855 -49.7,-0.2"
4164 class="st104"
4165 inkscape:label="SLC16A3_SLC16A1_SLC16A5_2 "
4166 inkscape:connector-curvature="0"
4167 id="R_SLC16A3_SLC16A1_SLC16A5_2" /><text
4168 style="font-size:16px;font-family:Calibri-Bold"
4169 id="text1116"
4170 class="st15 st16"
4171 x="1375.0873"
4172 y="814.86646">Formate</text>
4173 <text
4174 style="font-size:16px;font-family:Calibri-Bold"
4175 id="text1118"
4176 class="st15 st16"
4177 x="1501.4066"
4178 y="815.80499">Formate</text>
4179 <text
4180 style="font-size:10px;font-family:Calibri"
4181 id="text1120"
4182 class="st17 st18"
4183 x="485.40158"
4184 y="115.15945">ATP</text>
4185 <path
4186 style="fill:none;stroke:#000000;stroke-width:2.0948"
4187 d="m 467.4,101.01855 c 0,31.2 0,31.2 0,31.2 m 11.4,-18.7 c -7,-2.9 -11.5,3.3 -11.5,3.3 m 0.2,3.4 c 0.8,5.5 10.2,5.3 10.2,5.3"
4188 class="st76"
4189 inkscape:label="GCK_HKDC1_HK1_ADPGK_HK2_HK3 "
4190 inkscape:connector-curvature="0"
4191 id="R_GCK_HKDC1_HK1_ADPGK_HK2_HK3" /><path
4192 style="fill:none;stroke:#000000;stroke-width:1.67910004"
4193 d="m 467.6,565.81855 0,27.6 0,-27.6 z m 0,12.8 c 0.9,5 10.8,4.8 10.8,4.8 m 0.5,-11 c -6.9,-2.7 -11.3,3 -11.3,3"
4194 class="st105"
4195 inkscape:connector-curvature="0"
4196 id="R_PKM_TMEM54_PKLR_HCN3" /><path
4197 style="fill:none;stroke:#000000;stroke-width:2.0948"
4198 d="m 467.4,210.91855 0,31.1 0,-31.1 z m 0.3,14.8 c 0.9,5.5 11.1,5.3 11.1,5.3 m 3.7,-11.9 c -8.8,-2.9 -14.6,3.3 -14.6,3.3"
4199 class="st76"
4200 inkscape:connector-curvature="0"
4201 id="R_PFKP_PFKL_PFKM_1" /><path
4202 style="fill:none;stroke:#000000;stroke-width:2.0948"
4203 d="m 463.2,324.21855 0,37.2 0,-37.2 z m -0.3,18.2 c 1,5.5 11.8,5.2 11.8,5.2 m 2.5,-13 c -8.1,-2.9 -13.4,3.3 -13.4,3.3"
4204 class="st76"
4205 inkscape:connector-curvature="0"
4206 id="R_GAPDHS_GAPDH_GAPDHP29" /><path
4207 style="fill:none;stroke:#000000;stroke-width:2.0948"
4208 d="m 467.3,389.21855 0,37.2 0,-37.2 z m 0.4,15.4 c 0.8,5.6 9.7,5.3 9.7,5.3 m 2.5,-11.9 c -7.3,-3 -12,3.4 -12,3.4"
4209 class="st76"
4210 inkscape:connector-curvature="0"
4211 id="R_CRISP3_PGK1_MIA3_PGK2" /><path
4212 style="fill:none;stroke:#000000;stroke-width:1.81210005"
4213 d="m 467,524.81855 c 1.1,4.4 13,4.2 13,4.2 m -13.1,-13 c 0,24.3 0,24.3 0,24.3"
4214 class="st106"
4215 inkscape:label="R_ENO1_ENO3_ENO2 "
4216 inkscape:connector-curvature="0"
4217 id="R_ENO1_ENO3_ENO2" /><path
4218 style="fill:none;stroke:#000000;stroke-width:1.58019996"
4219 d="m 479.9,153.01855 45.9,0 -45.9,0 z m 33,8.4 c 2.6,-5.3 -3.5,-8.6 -3.5,-8.6 m -16.6,0.1 c -4.9,1.2 -4.4,12.7 -4.4,12.7"
4220 class="st107"
4221 inkscape:connector-curvature="0"
4222 id="R_G6PD" /><path
4223 style="fill:none;stroke:#000000;stroke-width:1.53460002"
4224 d="m 565.3,154.11855 c 7.9,0 15.7,0 23.6,0 m -8.7,0.1 c -1.9,0.2 -3.2,1.9 -3.9,3.4 -1.3,2.6 -1.9,5.6 -2.3,8.5"
4225 class="st108"
4226 inkscape:connector-curvature="0"
4227 id="R_H6PD_PGLS" /><path
4228 style="fill:none;stroke:#000000;stroke-width:1.82930005"
4229 d="m 638.3,154.51855 46.1,0 -46.1,0 z m 36.6,9.4 c 2.4,-5.6 -3.7,-9.1 -3.7,-9.1 m -23.3,-0.2 c -5,1.1 -4.3,12 -4.3,12"
4230 class="st109"
4231 inkscape:connector-curvature="0"
4232 id="R_PGD" /><path
4233 style="fill:none;stroke:#000000;stroke-width:1.61259997"
4234 d="m 968,293.11855 -0.2,25.4 m 12.8,-19.5 c -8.2,-1.5 -12.6,4.8 -12.6,4.8 m 0,2.6 c 1.7,4.8 13.1,3 13.1,3"
4235 class="st110"
4236 inkscape:label="CMPK2_CMPK1_1"
4237 inkscape:connector-curvature="0"
4238 id="R_CMPK2_CMPK1_1" /><path
4239 style="fill:none;stroke:#000000;stroke-width:2.54340005"
4240 d="m 759.4,333.41855 c 2.5,-0.6 3.4,-3.4 4,-5.6 0.5,-2.3 0.7,-4.7 0.7,-7 m -24.6,-0.6 c -1.6,4.5 -0.3,9.8 3.1,13.1 m -13.7,0 c 14.6,-0.1 29.2,-0.2 43.8,-0.3"
4241 class="st111"
4242 inkscape:connector-curvature="0"
4243 id="R_TYMS" /><path
4244 style="fill:none;stroke:#000000;stroke-width:1.75189996"
4245 d="m 1088.6,332.81855 c 5.1,-1 3.8,-8.7 3.8,-8.7 m -24.6,-2.4 c -1.7,7.1 3.5,11.2 3.5,11.2 m -16.1,0 49.8,0.2"
4246 class="st112"
4247 inkscape:connector-curvature="0"
4248 id="R_CTPS2_GATM_CTPS1" /><path
4249 style="fill:none;stroke:#000000;stroke-width:1.82930005"
4250 d="m 1146.5,332.61855 28.3,0.4 m -18.4,-9.2 c -2.2,5.6 3.9,8.9 3.9,8.9 m 4.8,0 c 5,-0.9 4,-8.9 4,-8.9"
4251 class="st109"
4252 inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4"
4253 inkscape:connector-curvature="0"
4254 id="R_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4" /><text
4255 style="font-size:14px;font-family:Calibri-Bold"
4256 id="text1135"
4257 class="st15 st38"
4258 transform="matrix(0.99980805,-0.01959226,0.01959226,0.99980805,0,0)"
4259 x="1196.0963"
4260 y="700.7312">H</text>
4261 <text
4262 style="font-size:13.99942493px;font-family:Calibri-Bold"
4263 id="text1137"
4264 class="st15 st38"
4265 transform="matrix(0.99984109,-0.01782667,0.01782667,0.99984109,0,0)"
4266 x="1194.2786"
4267 y="688.07074">Orn</text>
4268 <path
4269 style="fill:none;stroke:#000000;stroke-width:1.52830005"
4270 d="m 1425.4,612.11855 c 1,-2.3 0.5,-5 -1.1,-6.9 -0.6,-0.7 -1.2,-1.3 -1.9,-1.8 m -20,0.2 c -2.5,0.5 -3.6,3.7 -4.1,6.4 -0.3,2 -0.5,4.1 -0.4,6.1 m 34.9,-12.9 c -16.4,0.1 -32.8,0.1 -49.1,0.2"
4271 class="st113"
4272 inkscape:connector-curvature="0"
4273 id="R_PYCRL_PYCR2_PYCR1_LEFTY1_1" /><path
4274 style="fill:none;stroke:#000000;stroke-width:1.80159998"
4275 d="m 1428.9,640.21855 c 0.3,-6.1 -4.8,-8.7 -4.8,-8.7 m -22.3,0.4 c -3.9,-1.2 -5.4,12.6 -5.4,12.6 m -21.7,-31.8 0,19 75.8,0.1 0,-19"
4276 class="st114"
4277 inkscape:connector-curvature="0"
4278 id="R_PYCRL_PYCR2_PYCR1_LEFTY1_2" /><path
4279 style="fill:none;stroke:#000000;stroke-width:3.13759995"
4280 d="m 1050.3,713.41855 c 0,26.9 0,26.9 0,26.9 l -293.5,0 m 98.1,-9.5 c -1.8,5.9 2.3,9.7 2.3,9.7 m 33.9,-0.2 c 3.4,-1.3 3.1,-14.8 3.1,-14.8"
4281 class="st115"
4282 inkscape:connector-curvature="0"
4283 id="R_GLUD1_GLUD2_1" /><text
4284 style="font-size:10px;font-family:Calibri"
4285 id="text1142"
4286 class="st17 st18"
4287 transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
4288 x="904.09766"
4289 y="1005.4383">H</text>
4290 <text
4291 style="font-size:16px;font-family:Calibri-Bold"
4292 id="text1144"
4293 class="st15 st16"
4294 x="1486.4927"
4295 y="394.78244">PPi</text>
4296 <text
4297 style="font-size:10px;font-family:Calibri"
4298 id="text1146"
4299 class="st17 st18"
4300 x="1531.7222"
4301 y="374.82935">Pi</text>
4302 <text
4303 style="font-size:16px;font-family:Calibri-Bold"
4304 id="text1148"
4305 class="st15 st16"
4306 x="1554.2847"
4307 y="394.81766">Pi</text>
4308 <text
4309 style="font-size:10px;font-family:Calibri"
4310 id="text1150"
4311 class="st17 st18"
4312 x="1510.5044"
4313 y="374.69266">H</text>
4314 <text
4315 style="font-size:6.09369993px;font-family:Calibri"
4316 id="text1152"
4317 class="st17 st26"
4318 x="1516.7349"
4319 y="376.69266">2</text>
4320 <text
4321 style="font-size:10px;font-family:Calibri"
4322 id="text1154"
4323 class="st17 st18"
4324 x="1519.8237"
4325 y="374.69266">O</text>
4326 <text
4327 style="font-size:16px;font-family:Calibri-Bold"
4328 id="text1156"
4329 class="st15 st16"
4330 x="1484.4966"
4331 y="349.50125">CO</text>
4332 <text
4333 style="font-size:9.75px;font-family:Calibri-Bold"
4334 id="text1158"
4335 class="st15 st40"
4336 x="1503.6685"
4337 y="352.70145">2</text>
4338 <text
4339 style="font-size:16px;font-family:Calibri-Bold"
4340 id="text1160"
4341 class="st15 st16"
4342 x="1556.1343"
4343 y="349.02563">HCO</text>
4344 <text
4345 style="font-size:9.75px;font-family:Calibri-Bold"
4346 id="text1162"
4347 class="st15 st40"
4348 x="1585.3999"
4349 y="352.22586">3</text>
4350 <text
4351 style="font-size:9.75px;font-family:Calibri-Bold"
4352 id="text1164"
4353 class="st15 st40"
4354 x="1590.3413"
4355 y="340.22586">-</text>
4356 <path
4357 style="fill:none;stroke:#000000;stroke-width:1.80649996"
4358 d="m 1525.5,346.01855 c -5.4,-1.7 -4.9,-14 -4.9,-14 m 10.8,14.3 c 5.5,-1.1 4.1,-10.6 4.1,-10.6 m 9,10.6 -33.9,-0.3"
4359 class="st116"
4360 inkscape:label="CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13"
4361 inkscape:connector-curvature="0"
4362 id="R_CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13" /><text
4363 style="font-size:10px;font-family:Calibri"
4364 id="text1167"
4365 class="st17 st18"
4366 x="1532.2759"
4367 y="326.92114">H</text>
4368 <text
4369 style="font-size:10px;font-family:Calibri"
4370 id="text1169"
4371 class="st17 st18"
4372 x="1511.0825"
4373 y="328.17014">H</text>
4374 <text
4375 style="font-size:6.09369993px;font-family:Calibri"
4376 id="text1171"
4377 class="st17 st26"
4378 x="1517.313"
4379 y="330.17014">2</text>
4380 <text
4381 style="font-size:10px;font-family:Calibri"
4382 id="text1173"
4383 class="st17 st18"
4384 x="1520.4019"
4385 y="328.17014">O</text>
4386 <path
4387 style="fill:none;stroke:#000000;stroke-width:2.09949994"
4388 d="m 1424.9,550.31855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -9.1,-14.8 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.8,6.9 1.6,-1.7 1.6,1.8 z"
4389 class="st73"
4390 inkscape:label="AGAT forward"
4391 inkscape:connector-curvature="0"
4392 id="F_AGAT" /><path
4393 style="fill:none;stroke:#000000;stroke-width:2.16529989"
4394 d="m 1402.1,532.41855 c -2.7,9.7 3.5,15.9 3.5,15.9 m 3.4,-0.2 c 5.4,-1.2 4.9,-14.2 4.9,-14.2 m -25.2,14.2 39.4,0.1"
4395 class="st117"
4396 inkscape:connector-curvature="0"
4397 id="R_AGAT" /><path
4398 style="fill:none;stroke:#000000;stroke-width:2.09949994"
4399 d="m 1391.4,546.31855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z m 11.6,-10 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.8,6.9 1.6,-1.7 1.6,1.8 z"
4400 class="st73"
4401 inkscape:label="AGAT backward"
4402 inkscape:connector-curvature="0"
4403 id="B_AGAT" /><text
4404 style="font-size:16.00031662px;font-family:Calibri-Bold"
4405 id="text1178"
4406 class="st15 st16"
4407 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
4408 x="1439.4275"
4409 y="543.42334">Orn</text>
4410 <text
4411 style="font-size:16.00031662px;font-family:Calibri-Bold"
4412 id="text1180"
4413 class="st15 st16"
4414 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
4415 x="1360.4196"
4416 y="542.20752">Arg</text>
4417 <text
4418 style="font-size:10.00020409px;font-family:Calibri"
4419 id="text1182"
4420 class="st17 st18"
4421 transform="matrix(0.99997957,0.00639185,-0.00639185,0.99997957,0,0)"
4422 x="1391.7148"
4423 y="578.39606">H</text>
4424 <text
4425 style="font-size:6.09382439px;font-family:Calibri"
4426 id="text1184"
4427 class="st17 st26"
4428 transform="matrix(0.99997957,0.00639185,-0.00639185,0.99997957,0,0)"
4429 x="1397.9453"
4430 y="580.39606">2</text>
4431 <text
4432 style="font-size:10.00020409px;font-family:Calibri"
4433 id="text1186"
4434 class="st17 st18"
4435 transform="matrix(0.99997957,0.00639185,-0.00639185,0.99997957,0,0)"
4436 x="1401.0333"
4437 y="578.396">O</text>
4438 <text
4439 style="font-size:10.000103px;font-family:Calibri"
4440 id="text1188"
4441 class="st17 st18"
4442 transform="matrix(0.99968968,0.0249107,-0.0249107,0.99968968,0,0)"
4443 x="1421.3773"
4444 y="552.20471">NH</text>
4445 <text
4446 style="font-size:6.09376287px;font-family:Calibri"
4447 id="text1190"
4448 class="st17 st26"
4449 transform="matrix(0.99968968,0.0249107,-0.0249107,0.99968968,0,0)"
4450 x="1434.0627"
4451 y="554.20477">3</text>
4452 <path
4453 style="fill:none;stroke:#000000;stroke-width:1.58570004"
4454 d="m 1372.7,556.21855 0,8 59.7,0 m -27.9,0.1 c -5.2,1.1 -4.6,11.9 -4.6,11.9 m 11.8,-2.8 c 1.3,-5.8 -4.6,-9 -4.6,-9"
4455 class="st118"
4456 inkscape:connector-curvature="0"
4457 id="R_arginineAmidinohydrolase" /><text
4458 style="font-size:16.00031662px;font-family:Calibri-Bold"
4459 id="text1193"
4460 class="st15 st16"
4461 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
4462 x="1443.032"
4463 y="560.49847">Ci</text>
4464 <text
4465 style="font-size:16px;font-family:Calibri-Bold"
4466 id="text1195"
4467 class="st15 st16"
4468 x="141.67799"
4469 y="620.84399">Asn</text>
4470 <text
4471 style="font-size:10px;font-family:Calibri"
4472 id="text1197"
4473 class="st17 st18"
4474 x="169.63359"
4475 y="597.4563">Glu</text>
4476 <text
4477 style="font-size:10px;font-family:Calibri"
4478 id="text1199"
4479 class="st17 st18"
4480 x="183.491"
4481 y="597.4563">+</text>
4482 <text
4483 style="font-size:10px;font-family:Calibri"
4484 id="text1201"
4485 class="st17 st18"
4486 x="188.4715"
4487 y="597.4563">AMP</text>
4488 <text
4489 style="font-size:10px;font-family:Calibri"
4490 id="text1203"
4491 class="st17 st18"
4492 x="207.97339"
4493 y="597.4563">+</text>
4494 <text
4495 style="font-size:10px;font-family:Calibri"
4496 id="text1205"
4497 class="st17 st18"
4498 x="212.95389"
4499 y="597.4563">PPi</text>
4500 <text
4501 style="font-size:10px;font-family:Calibri"
4502 id="text1207"
4503 class="st17 st18"
4504 x="235.44168"
4505 y="597.802">Gln+ATP+H</text>
4506 <text
4507 style="font-size:6.09369993px;font-family:Calibri"
4508 id="text1209"
4509 class="st17 st26"
4510 x="280.53448"
4511 y="599.802">2</text>
4512 <text
4513 style="font-size:10px;font-family:Calibri"
4514 id="text1211"
4515 class="st17 st18"
4516 x="283.6228"
4517 y="597.802">O</text>
4518 <path
4519 style="fill:none;stroke:#000000;stroke-width:2.13490009"
4520 d="m 177.6,614.01855 c 45.3,0 90.7,0.1 136,0.1 m -53.3,-0.7 c 4.3,-2.2 4.3,-7.9 4.6,-12.1 l 0,-0.6 0,-0.5 m -62.9,4.2 c -1.9,3.5 0.5,7.2 3.5,9.1"
4521 class="st119"
4522 inkscape:connector-curvature="0"
4523 id="R_ASNS" /><text
4524 style="font-size:10px;font-family:Calibri"
4525 id="text1214"
4526 class="st17 st18"
4527 x="178.00999"
4528 y="646.13007">H</text>
4529 <text
4530 style="font-size:6.09369993px;font-family:Calibri"
4531 id="text1216"
4532 class="st17 st26"
4533 x="184.24049"
4534 y="648.13007">2</text>
4535 <text
4536 style="font-size:10px;font-family:Calibri"
4537 id="text1218"
4538 class="st17 st18"
4539 x="187.32939"
4540 y="646.13007">O</text>
4541 <text
4542 style="font-size:10px;font-family:Calibri"
4543 id="text1220"
4544 class="st17 st18"
4545 x="215.13109"
4546 y="645.87531">NH</text>
4547 <text
4548 style="font-size:6.09369993px;font-family:Calibri"
4549 id="text1222"
4550 class="st17 st26"
4551 x="227.8167"
4552 y="647.87531">3</text>
4553 <text
4554 style="font-size:16px;font-family:Calibri-Bold"
4555 id="text1224"
4556 class="st15 st16"
4557 x="312.49149"
4558 y="443.98465">Fum</text>
4559 <text
4560 style="font-size:16px;font-family:Calibri-Bold"
4561 id="text1226"
4562 class="st15 st16"
4563 x="311.30301"
4564 y="503.79126">Mal</text>
4565 <text
4566 style="font-size:10px;font-family:Calibri"
4567 id="text1228"
4568 class="st17 st18"
4569 x="289.62579"
4570 y="470.02274">H</text>
4571 <text
4572 style="font-size:6.09369993px;font-family:Calibri"
4573 id="text1230"
4574 class="st17 st26"
4575 x="295.8562"
4576 y="472.02274">2</text>
4577 <text
4578 style="font-size:10px;font-family:Calibri"
4579 id="text1232"
4580 class="st17 st18"
4581 x="298.94458"
4582 y="470.02274">O</text>
4583 <text
4584 style="font-size:16px;font-family:Calibri-Bold"
4585 id="text1234"
4586 class="st15 st16"
4587 x="310.03931"
4588 y="565.5257">OAA</text>
4589 <text
4590 style="font-size:10px;font-family:Calibri"
4591 id="text1236"
4592 class="st17 st18"
4593 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
4594 x="364.86237"
4595 y="538.48999">GTP</text>
4596 <text
4597 style="font-size:9.99962234px;font-family:Calibri"
4598 id="text1238"
4599 class="st17 st18"
4600 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
4601 x="378.13837"
4602 y="544.30634">GDP+CO</text>
4603 <text
4604 style="font-size:6.09346962px;font-family:Calibri"
4605 id="text1240"
4606 class="st17 st26"
4607 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
4608 x="412.61111"
4609 y="546.30634">2</text>
4610 <path
4611 style="fill:none;stroke:#000000;stroke-width:2.3204"
4612 d="m 397.8,557.61855 c 6.3,-1 6,-11.8 6,-11.8 m -31.2,-3.5 c -2.3,9.4 2.6,15.5 2.6,15.5 m 62.1,-0.2 -98.3,0.2"
4613 class="st120"
4614 inkscape:connector-curvature="0"
4615 id="R_PEPCK" /><text
4616 style="font-size:16px;font-family:Calibri-Bold"
4617 id="text1243"
4618 class="st15 st16"
4619 x="562.0647"
4620 y="582.62531">Iso</text>
4621 <text
4622 style="font-size:10px;font-family:Calibri"
4623 id="text1245"
4624 class="st17 st18"
4625 x="583.12042"
4626 y="558.49048">NADPH</text>
4627 <text
4628 style="font-size:16px;font-family:Calibri-Bold"
4629 id="text1247"
4630 class="st15 st16"
4631 x="666.13904"
4632 y="582.9212">AKG</text>
4633 <text
4634 style="font-size:10px;font-family:Calibri"
4635 id="text1249"
4636 class="st17 st18"
4637 x="584.34894"
4638 y="600.24438">NADP</text>
4639 <text
4640 style="font-size:10px;font-family:Calibri"
4641 id="text1251"
4642 class="st17 st18"
4643 x="634.66632"
4644 y="558.13007">CO</text>
4645 <text
4646 style="font-size:6.09369993px;font-family:Calibri"
4647 id="text1253"
4648 class="st17 st26"
4649 x="646.53149"
4650 y="560.13007">2</text>
4651 <text
4652 style="font-size:16px;font-family:Calibri-Bold"
4653 id="text1255"
4654 class="st15 st16"
4655 x="254.8035"
4656 y="672.10089">Fum</text>
4657 <text
4658 style="font-size:10px;font-family:Calibri"
4659 id="text1257"
4660 class="st17 st18"
4661 x="235.65359"
4662 y="644.21405">NH</text>
4663 <text
4664 style="font-size:6.09369993px;font-family:Calibri"
4665 id="text1259"
4666 class="st17 st26"
4667 x="248.33908"
4668 y="646.21405">3</text>
4669 <text
4670 style="font-size:16px;font-family:Calibri-Bold"
4671 id="text1261"
4672 class="st15 st16"
4673 x="354.87671"
4674 y="645.8938">Ala</text>
4675 <path
4676 style="fill:none;stroke:#000000;stroke-width:2.09949994"
4677 d="m 430.6,634.41855 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.7,6.9 1.6,-1.7 1.5,1.8 z m 25.2,-8.7 c -2.2,-6.3 -2.2,-6.3 -2.2,-6.3 l -1.7,6.5 1.9,-1.7 2,1.5 z"
4678 class="st73"
4679 inkscape:label="NIT2 b"
4680 inkscape:connector-curvature="0"
4681 id="B_NIT2" /><path
4682 style="fill:none;stroke:#000000;stroke-width:2.09949994"
4683 d="m 410.3,635.21855 c -0.5,-2.3 -1,-4.7 -1.4,-7 -0.6,2.3 -1.2,4.6 -1.7,6.9 0.5,-0.6 1.1,-1.1 1.6,-1.7 0.4,0.6 1,1.2 1.5,1.8 l 0,0 z m -21.4,4.9 c -2.5,0.6 -4.9,1.3 -7.4,1.9 2.4,0.8 4.8,1.6 7.2,2.4 -0.6,-0.7 -1.2,-1.5 -1.8,-2.2 0.8,-0.7 1.4,-1.4 2,-2.1 l 0,0 z"
4684 class="st73"
4685 inkscape:label="NIT2"
4686 inkscape:connector-curvature="0"
4687 id="F_NIT2" /><text
4688 style="font-size:10px;font-family:Calibri"
4689 id="text1265"
4690 class="st17 st18"
4691 x="396.95239"
4692 y="626.41815">AKG</text>
4693 <text
4694 style="font-size:10px;font-family:Calibri"
4695 id="text1267"
4696 class="st17 st18"
4697 x="420.85379"
4698 y="626.40259">Glu</text>
4699 <text
4700 style="font-size:16px;font-family:Calibri-Bold"
4701 id="text1269"
4702 class="st15 st16"
4703 x="409.09311"
4704 y="1219.8303">Biomass</text>
4705 <path
4706 style="fill:none;stroke:#000000;stroke-width:2.22930002"
4707 d="m 434.5,1275.0186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
4708 class="st69"
4709 inkscape:label="biomass_synthesis f"
4710 inkscape:connector-curvature="0"
4711 id="F_biomass_synthesis" /><path
4712 style="fill:none;stroke:#000000;stroke-width:2.22930002"
4713 d="m 436.5,1224.9186 0,50.5"
4714 class="st69"
4715 inkscape:label="biomass_synthesis"
4716 inkscape:connector-curvature="0"
4717 id="R_biomass_synthesis" /><path
4718 style="fill:none;stroke:#000000;stroke-width:1.68139994"
4719 d="m 407.6,610.21855 c -5.4,-0.8 -5.1,-9.5 -5.1,-9.5 m 35.5,-3.8 c 2.8,7.9 -3.2,13.1 -3.2,13.1 m 14.4,-0.2 c -62.3,0 -62.3,0 -62.3,0"
4720 class="st121"
4721 inkscape:label="#R_LDHD"
4722 inkscape:connector-curvature="0"
4723 id="R_LDH" /><text
4724 style="font-size:10px;font-family:Calibri"
4725 id="text1274"
4726 class="st17 st18"
4727 x="657.13702"
4728 y="176.49825">NADPH+</text>
4729 <text
4730 style="font-size:10px;font-family:Calibri"
4731 id="text1276"
4732 class="st17 st18"
4733 x="657.13702"
4734 y="188.99825">H+CO2</text>
4735 <text
4736 style="font-size:10px;font-family:Calibri"
4737 id="text1278"
4738 class="st17 st18"
4739 x="498.32352"
4740 y="174.68045">NADPH</text>
4741 <text
4742 style="font-size:10px;font-family:Calibri"
4743 id="text1280"
4744 class="st17 st18"
4745 x="528.11365"
4746 y="174.68045">+H</text>
4747 <text
4748 style="font-size:10px;font-family:Calibri"
4749 id="text1282"
4750 class="st17 st18"
4751 x="420.31329"
4752 y="593.42896">NADH</text>
4753 <text
4754 style="font-size:10px;font-family:Calibri"
4755 id="text1284"
4756 class="st17 st18"
4757 x="444.93729"
4758 y="593.42896">+</text>
4759 <text
4760 style="font-size:10px;font-family:Calibri"
4761 id="text1286"
4762 class="st17 st18"
4763 x="449.91779"
4764 y="593.42896">H</text>
4765 <path
4766 style="fill:none;stroke:#000000;stroke-width:2.90479994"
4767 inkscape:connector-curvature="0"
4768 d="m 467.5,711.91855 -0.2,-89.3 m 0.3,71.6 c 1.4,5.7 13.2,4.2 13.2,4.2 m -13.5,-30 c -1.7,-4.3 -14.4,-3.9 -14.4,-3.9"
4769 class="st122"
4770 id="R_MPC1_MPC2_MPC1L" /><path
4771 style="fill:none;stroke:#000000;stroke-width:2.09949994"
4772 d="m 465,710.11855 c 2.3,6.3 2.3,6.3 2.3,6.3 l 1.6,-6.5 -1.9,1.7 -2,-1.5 z"
4773 class="st73"
4774 inkscape:label="MPC1_MPC2_MPC1L forward"
4775 inkscape:connector-curvature="0"
4776 id="F_MPC1_MPC2_MPC1L" /><text
4777 style="font-size:10px;font-family:Calibri"
4778 id="text1290"
4779 class="st17 st18"
4780 x="432.4104"
4781 y="750.59888">NAD</text>
4782 <text
4783 style="font-size:10px;font-family:Calibri"
4784 id="text1292"
4785 class="st17 st18"
4786 x="434.51151"
4787 y="767.7298">CoA</text>
4788 <text
4789 style="font-size:10px;font-family:Calibri"
4790 id="text1294"
4791 class="st17 st18"
4792 x="485.1048"
4793 y="782.6712">CO</text>
4794 <text
4795 style="font-size:6.09369993px;font-family:Calibri"
4796 id="text1296"
4797 class="st17 st26"
4798 x="496.97"
4799 y="784.6712">2</text>
4800 <text
4801 style="font-size:10px;font-family:Calibri"
4802 id="text1298"
4803 class="st17 st18"
4804 x="484.4744"
4805 y="761.19745">NADH</text>
4806 <text
4807 style="font-size:10px;font-family:Calibri"
4808 id="text1300"
4809 class="st17 st18"
4810 x="485.61499"
4811 y="772.3714">H</text>
4812 <text
4813 style="font-size:10px;font-family:Calibri"
4814 id="text1302"
4815 class="st17 st18"
4816 x="580.08624"
4817 y="699.8714">Mal</text>
4818 <text
4819 style="font-size:10px;font-family:Calibri"
4820 id="text1304"
4821 class="st17 st18"
4822 x="520.5755"
4823 y="664.80096">Mal</text>
4824 <path
4825 style="fill:none;stroke:#000000;stroke-width:2.25819993"
4826 d="m 559.6,784.71855 -0.1,-252.5 m 0.1,159.4 c 1.4,5.6 13.3,4.2 13.3,4.2 m -13.4,-29.7 c -1.7,-4.2 -14.5,-3.9 -14.5,-3.9"
4827 class="st123"
4828 inkscape:label="SLC25A1"
4829 inkscape:connector-curvature="0"
4830 id="R_SLC25A1" /><text
4831 style="font-size:16px;font-family:Calibri-Bold"
4832 id="text1307"
4833 class="st15 st16"
4834 x="554.77374"
4835 y="523.11255">Cit</text>
4836 <path
4837 style="fill:none;stroke:#000000;stroke-width:2.18210006"
4838 d="m 568.4,536.41855 c 2.2,-7.3 2.2,-7.3 2.2,-7.3 l 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
4839 class="st14"
4840 inkscape:label="ACO1_IREB2 b"
4841 inkscape:connector-curvature="0"
4842 id="B_ACO1_IREB2" /><path
4843 style="fill:none;stroke:#000000;stroke-width:2.18210006"
4844 d="m 568.6,562.11855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
4845 class="st14"
4846 inkscape:label="ACO1_IREB2 f"
4847 inkscape:connector-curvature="0"
4848 id="F_ACO1_IREB2" /><path
4849 style="fill:none;stroke:#000000;stroke-width:1.92060006"
4850 d="m 570.4,535.51855 c 0,27.3 0,27.3 0,27.3"
4851 class="st124"
4852 inkscape:label="ACO1_IREB2"
4853 inkscape:connector-curvature="0"
4854 id="R_ACO1_IREB2" /><text
4855 style="font-size:10px;font-family:Calibri"
4856 id="text1312"
4857 class="st17 st18"
4858 x="887.51202"
4859 y="262.06564">2 Pi</text>
4860 <path
4861 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4862 d="m 477.8,123.71855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12.4,8 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
4863 class="st30"
4864 inkscape:label="GCK_HKDC1_HK1_ADPGK_HK2_HK3 f"
4865 inkscape:connector-curvature="0"
4866 id="F_GCK_HKDC1_HK1_ADPGK_HK2_HK3" /><path
4867 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4868 d="m 477.8,229.21855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12,10.7 c 1.7,7.3 1.7,7.3 1.7,7.3 l 1.7,-7.3 -1.7,1.8 -1.7,-1.8 z"
4869 class="st30"
4870 inkscape:label="PFKP_PFKL_PFKM_1 f"
4871 inkscape:connector-curvature="0"
4872 id="F_PFKP_PFKL_PFKM_1" /><path
4873 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4874 d="m 473.7,345.71855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12.6,13.6 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
4875 class="st30"
4876 inkscape:label="GAPDHS_GAPDH_GAPDHP29"
4877 inkscape:connector-curvature="0"
4878 id="F_GAPDHS_GAPDH_GAPDHP29" /><path
4879 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4880 d="m 479.8,527.21855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -14.7,10.9 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
4881 class="st30"
4882 inkscape:label="ENO1_ENO3_ENO2 f"
4883 inkscape:connector-curvature="0"
4884 id="F_ENO1_ENO3_ENO2" /><path
4885 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4886 d="m 477.9,581.61855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12.4,10.4 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
4887 class="st30"
4888 inkscape:label="PKM_TMEM54_PKLR_HCN3 f"
4889 inkscape:connector-curvature="0"
4890 id="F_PKM_TMEM54_PKLR_HCN3" /><path
4891 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4892 d="m 403.9,602.11855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -15.8,5.8 -7.3,2.2 7.3,2.2 -1.8,-2.2 1.8,-2.2 z"
4893 class="st30"
4894 inkscape:label="LDH f"
4895 inkscape:connector-curvature="0"
4896 id="F_LDH" /><path
4897 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4898 d="m 514.9,160.51855 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m 6.5,-5.4 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.2 1.8,2.2 -1.8,2.2 z"
4899 class="st30"
4900 inkscape:label="G6PD"
4901 inkscape:connector-curvature="0"
4902 id="F_G6PD" /><path
4903 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4904 d="m 676.8,162.21855 c -1,5.2 -1,5.2 -1,5.2 l -2.4,-5.3 1.9,1.3 1.5,-1.2 z m 5.2,-5.6 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.2 1.8,2.2 -1.8,2.2 z"
4905 class="st30"
4906 inkscape:label="PGD f"
4907 inkscape:connector-curvature="0"
4908 id="F_PGD" /><path
4909 style="fill:none;stroke:#000000;stroke-width:2.09750009"
4910 d="m 790.5,176.41855 c 0,29.5 0,29.5 0,29.5 m -12.7,-23.8 c 7.8,-2.3 12.6,3.5 12.6,3.5 m -0.3,7 c -1,5 -10.4,4.3 -10.4,4.3"
4911 class="st125"
4912 inkscape:label="PRPS2_PRPS1_PRPS1L1"
4913 inkscape:connector-curvature="0"
4914 id="R_PRPS2_PRPS1_PRPS1L1" /><path
4915 style="fill:none;stroke:#000000;stroke-width:2.44919991"
4916 d="m 764.8,168.11855 c 7.2,-0.3 7.2,-0.3 7.2,-0.3 l -6.1,-3.9 1.1,2.6 -2.2,1.6 z"
4917 class="st32"
4918 inkscape:transform-center-y="13.19671"
4919 inkscape:transform-center-x="-17.870394"
4920 inkscape:label="RPIA_LOC101060545 f"
4921 inkscape:connector-curvature="0"
4922 id="F_RPIA_LOC101060545" /><path
4923 style="fill:none;stroke:#000000;stroke-width:1.17589998"
4924 d="m 732.7,157.71855 33.8,8.2"
4925 class="st126"
4926 inkscape:transform-center-y="9.1713454"
4927 inkscape:transform-center-x="7.5511886"
4928 inkscape:label="RPIA_LOC101060545"
4929 inkscape:connector-curvature="0"
4930 id="R_RPIA_LOC101060545" /><path
4931 style="fill:none;stroke:#000000;stroke-width:1.13479996"
4932 d="m 739,148.51855 32,-6.4"
4933 class="st127"
4934 inkscape:transform-center-y="-9.5755519"
4935 inkscape:transform-center-x="6.2972653"
4936 inkscape:label="RPE_LOC729020"
4937 inkscape:connector-curvature="0"
4938 id="R_RPE_LOC729020" /><path
4939 style="fill:none;stroke:#000000;stroke-width:2.44919991"
4940 d="m 740.3,146.41855 c -6.6,2.9 -6.6,2.9 -6.6,2.9 l 7.1,1.5 -1.9,-2 1.4,-2.4 z"
4941 class="st32"
4942 inkscape:transform-center-y="-7.1245069"
4943 inkscape:transform-center-x="22.076699"
4944 inkscape:label="RPE_LOC729020 f"
4945 inkscape:connector-curvature="0"
4946 id="F_RPE_LOC729020" /><path
4947 style="fill:none;stroke:#000000;stroke-width:1.87170005"
4948 d="m 780.2,198.61855 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z m 12.4,6.6 c -2,6.9 -2,6.9 -2,6.9 l -2.4,-6.8 2.2,1.7 2.2,-1.8 z"
4949 class="st30"
4950 inkscape:label="PRPS2_PRPS1_PRPS1L1 f"
4951 inkscape:connector-curvature="0"
4952 id="F_PRPS2_PRPS1_PRPS1L1" /><text
4953 style="font-size:10px;font-family:Calibri"
4954 id="text1328"
4955 class="st17 st18"
4956 x="928.5589"
4957 y="209.07054">4 Pi</text>
4958 <path
4959 style="fill:none;stroke:#000000;stroke-width:2.00309992"
4960 d="m 628.9,518.91855 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m -6.4,-11.7 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 12.1,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 14.1,11.6 -72.4,-0.2 m 19.7,-0.3 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.3,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
4961 class="st128"
4962 inkscape:label="ACLY"
4963 inkscape:connector-curvature="0"
4964 id="R_ACLY" /><text
4965 style="font-size:10px;font-family:Calibri"
4966 id="text1331"
4967 class="st17 st18"
4968 x="619.48761"
4969 y="501.60864">Pi</text>
4970 <text
4971 style="font-size:10px;font-family:Calibri"
4972 id="text1333"
4973 class="st17 st18"
4974 x="925.4632"
4975 y="502.06665">CoA</text>
4976 <text
4977 style="font-size:10px;font-family:Calibri"
4978 id="text1335"
4979 class="st17 st18"
4980 x="978.2464"
4981 y="502.37036">3ADP</text>
4982 <text
4983 style="font-size:10px;font-family:Calibri"
4984 id="text1337"
4985 class="st17 st18"
4986 x="944.37335"
4987 y="502.11053">2 NADP</text>
4988 <text
4989 style="font-size:10px;font-family:Calibri"
4990 id="text1339"
4991 class="st17 st18"
4992 x="1005.5902"
4993 y="502.01004">Pi</text>
4994 <text
4995 style="font-size:10px;font-family:Calibri"
4996 id="text1341"
4997 class="st17 st18"
4998 x="1022.222"
4999 y="502.37036">CO2</text>
5000 <text
5001 style="font-size:10px;font-family:Calibri"
5002 id="text1343"
5003 class="st17 st18"
5004 x="935.09015"
5005 y="537.14966">2 NADPH</text>
5006 <path
5007 style="fill:none;stroke:#000000;stroke-width:2.00309992"
5008 d="m 990.8,518.11855 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 37.1,-11.1 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m -20.9,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m -56.6,11.1 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 5.6,-11.1 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 28.6,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 42.5,11.6 -117.3,-0.2 m 10.7,-0.3 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 4.3,-11 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
5009 class="st128"
5010 inkscape:label="MVD"
5011 inkscape:connector-curvature="0"
5012 id="R_MVD" /><text
5013 style="font-size:10px;font-family:Calibri"
5014 id="text1346"
5015 class="st17 st18"
5016 x="916.46899"
5017 y="537.34601">2 H</text>
5018 <text
5019 style="font-size:10px;font-family:Calibri"
5020 id="text1348"
5021 class="st17 st18"
5022 x="975.79724"
5023 y="537.38495">3 ATP</text>
5024 <text
5025 style="font-size:10px;font-family:Calibri"
5026 id="text1350"
5027 class="st17 st18"
5028 x="1083.433"
5029 y="539.12915">2 ippPP</text>
5030 <text
5031 style="font-size:10px;font-family:Calibri"
5032 id="text1352"
5033 class="st17 st18"
5034 x="1092.3324"
5035 y="502.40256">2 PPi</text>
5036 <path
5037 style="fill:none;stroke:#000000;stroke-width:1.96599996"
5038 d="m 1113.5,519.01855 -25,-0.5 m 13.7,-0.2 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.2,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
5039 class="st129"
5040 inkscape:label="ARID4B_GGPS1_FDPS_FDPSP7_2"
5041 inkscape:connector-curvature="0"
5042 id="R_ARID4B_GGPS1_FDPS_FDPSP7_2" /><text
5043 style="font-size:10px;font-family:Calibri"
5044 id="text1355"
5045 class="st17 st18"
5046 x="1146.4008"
5047 y="536.18677">fPP</text>
5048 <text
5049 style="font-size:10px;font-family:Calibri"
5050 id="text1357"
5051 class="st17 st18"
5052 x="1147.5316"
5053 y="500.91135">15 H</text>
5054 <text
5055 style="font-size:6.09369993px;font-family:Calibri"
5056 id="text1359"
5057 class="st17 st26"
5058 x="1166.1605"
5059 y="502.91135">2</text>
5060 <text
5061 style="font-size:10px;font-family:Calibri"
5062 id="text1361"
5063 class="st17 st18"
5064 x="1169.2484"
5065 y="500.91135">O</text>
5066 <text
5067 style="font-size:10px;font-family:Calibri"
5068 id="text1363"
5069 class="st17 st18"
5070 x="1244.015"
5071 y="500.13596">2 PPi</text>
5072 <text
5073 style="font-size:10px;font-family:Calibri"
5074 id="text1365"
5075 class="st17 st18"
5076 x="1178.6937"
5077 y="500.73166">13 NADP</text>
5078 <text
5079 style="font-size:10px;font-family:Calibri"
5080 id="text1367"
5081 class="st17 st18"
5082 x="1269.6381"
5083 y="499.95636">for</text>
5084 <text
5085 style="font-size:10px;font-family:Calibri"
5086 id="text1369"
5087 class="st17 st18"
5088 x="1219.3802"
5089 y="500.49734">2 CO</text>
5090 <text
5091 style="font-size:6.09369993px;font-family:Calibri"
5092 id="text1371"
5093 class="st17 st26"
5094 x="1238.5746"
5095 y="502.49734">2</text>
5096 <text
5097 style="font-size:10px;font-family:Calibri"
5098 id="text1373"
5099 class="st17 st18"
5100 x="1162.7885"
5101 y="536.02271">13 NADPH</text>
5102 <text
5103 style="font-size:10px;font-family:Calibri"
5104 id="text1375"
5105 class="st17 st18"
5106 x="1208.9027"
5107 y="536.07941">16 H</text>
5108 <text
5109 style="font-size:10px;font-family:Calibri"
5110 id="text1377"
5111 class="st17 st18"
5112 x="1230.308"
5113 y="535.75806">10 O</text>
5114 <text
5115 style="font-size:6.09369993px;font-family:Calibri"
5116 id="text1379"
5117 class="st17 st26"
5118 x="1249.3265"
5119 y="537.75806">2</text>
5120 <path
5121 style="fill:none;stroke:#000000;stroke-width:1.82200003"
5122 d="m 861.2,464.41855 c 5.9,-1 4.4,-9.6 4.4,-9.6 m -19,9.5 29.3,0.3 m -15.1,-0.1 c -6,1.2 -5.5,10.5 -5.5,10.5"
5123 class="st130"
5124 inkscape:label="MCAT_FASN"
5125 inkscape:connector-curvature="0"
5126 id="R_MCAT_FASN" /><text
5127 style="font-size:10px;font-family:Calibri"
5128 id="text1382"
5129 class="st17 st18"
5130 x="1064.4486"
5131 y="447.78546">14 H</text>
5132 <path
5133 style="fill:none;stroke:#000000;stroke-width:1.87170005"
5134 d="m 888.8,422.31855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -27.6,0.3 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 39.9,9.6 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
5135 class="st30"
5136 inkscape:label="AcAcACPSynthesis f"
5137 inkscape:connector-curvature="0"
5138 id="F_AcAcACPSynthesis" /><path
5139 style="fill:none;stroke:#000000;stroke-width:1.87170005"
5140 d="m 477.8,777.11855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m 0,-10.5 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m 0,-10.5 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -10.5,38.3 c -2.1,6.9 -2.1,6.9 -2.1,6.9 l -2.3,-6.8 2.2,1.7 2.2,-1.8 z"
5141 class="st30"
5142 inkscape:label="DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB F"
5143 inkscape:connector-curvature="0"
5144 id="F_DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB" /><path
5145 style="fill:none;stroke:#000000;stroke-width:2.37849998"
5146 d="m 443.6,735.91855 -27.4,0 0,127.5 116.3,0 m -60.4,0.2 c 7.3,-1.5 7.3,-12.6 7.3,-12.6 m 17.7,12.5 c -7.6,1.4 -8.5,11 -8.5,11 m -25.1,-11 c -7.6,1.4 -8.5,11 -8.5,11 m -15.9,-11 c -7.6,1.4 -8.5,11 -8.5,11 m 8.7,-11.2 c 7.3,-1.5 7.3,-12.6 7.3,-12.6"
5147 class="st131"
5148 inkscape:label="PC"
5149 inkscape:connector-curvature="0"
5150 id="R_PC" /><text
5151 style="font-size:10px;font-family:Calibri"
5152 id="text1387"
5153 class="st17 st18"
5154 x="437.9422"
5155 y="842.4212">ADP</text>
5156 <text
5157 style="font-size:10px;font-family:Calibri"
5158 id="text1389"
5159 class="st17 st18"
5160 x="475.73709"
5161 y="842.85181">Pi</text>
5162 <text
5163 style="font-size:10px;font-family:Calibri"
5164 id="text1391"
5165 class="st17 st18"
5166 x="420.13361"
5167 y="882.27466">ATP</text>
5168 <text
5169 style="font-size:10px;font-family:Calibri"
5170 id="text1393"
5171 class="st17 st18"
5172 x="444.71021"
5173 y="881.94067">HCO</text>
5174 <text
5175 style="font-size:6.09369993px;font-family:Calibri"
5176 id="text1395"
5177 class="st17 st26"
5178 x="462.80591"
5179 y="883.94067">3</text>
5180 <text
5181 style="font-size:6.09369993px;font-family:Calibri"
5182 id="text1397"
5183 class="st17 st26"
5184 x="465.89481"
5185 y="876.44067">-</text>
5186 <text
5187 style="font-size:10px;font-family:Calibri"
5188 id="text1399"
5189 class="st17 st18"
5190 x="485.21021"
5191 y="881.94067">H</text>
5192 <path
5193 style="fill:none;stroke:#000000;stroke-width:2.44919991"
5194 d="m 530.5,861.11855 c 6.9,2.1 6.9,2.1 6.9,2.1 l -6.8,2.3 1.7,-2.2 -1.8,-2.2 z m -86,-10.4 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 33,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
5195 class="st32"
5196 inkscape:label="PC f"
5197 inkscape:connector-curvature="0"
5198 id="F_PC" /><path
5199 style="fill:none;stroke:#000000;stroke-width:1.53359997"
5200 d="m 562.6,822.11855 c 4.2,1.1 4.2,1.1 4.2,1.1 l -4.4,1.6 1.2,-1.4 -1,-1.3 z m -6.5,-9.6 c 0.1,-5.5 0.1,-5.5 0.1,-5.5 l -3.5,4.6 2.1,-0.8 1.3,1.7 z"
5201 class="st132"
5202 inkscape:label="CS f"
5203 inkscape:connector-curvature="0"
5204 id="F_CS" /><text
5205 style="font-size:10px;font-family:Calibri"
5206 id="text1403"
5207 class="st17 st18"
5208 x="681.67023"
5209 y="783.07056">H</text>
5210 <text
5211 style="font-size:10px;font-family:Calibri"
5212 id="text1405"
5213 class="st17 st18"
5214 x="683.4339"
5215 y="716.35669">H</text>
5216 <path
5217 style="fill:none;stroke:#000000;stroke-width:1.49890006"
5218 d="m 662.8,725.01855 c -1,6.8 -7.1,8.5 -7.1,8.5 m 45.3,-7.2 c -1,6.8 -7.1,8.5 -7.1,8.5 m -8.9,-11 c -1,6.8 -7.1,8.5 -7.1,8.5 m -39,-5.5 c 1,6.8 7.1,8.5 7.1,8.5 m -13.6,3.7 c 26,-9.2 53,-8.9 79.3,1"
5219 class="st133"
5220 inkscape:label="IDH2"
5221 inkscape:connector-curvature="0"
5222 id="R_IDH2" /><path
5223 style="fill:none;stroke:#000000;stroke-width:1.81630003"
5224 d="m 638.9,767.21855 c -3.8,4 -3.8,4 -3.8,4 l 1.6,-6.8 0.4,2.8 1.8,0 z m -5.4,-13.8 c -6.3,-1.4 -6.3,-1.4 -6.3,-1.4 l 4.4,4.1 -0.4,-2 2.3,-0.7 z"
5225 class="st134"
5226 inkscape:label="IDH3 b"
5227 inkscape:connector-curvature="0"
5228 id="B_IDH3" /><path
5229 style="fill:none;stroke:#000000;stroke-width:1.49890006"
5230 d="m 632.4,755.01855 c 26,9.2 53,8.9 79.3,-1 m -74.1,13.2 c 1,-6.8 7.1,-8.5 7.1,-8.5 m 40.3,11 c -1,-6.8 -7.1,-8.5 -7.1,-8.5 m 23.1,6 c -1,-6.8 -7.1,-8.5 -7.1,-8.5 m -29.9,10.7 c -1,-6.8 -7.1,-8.5 -7.1,-8.5"
5231 class="st133"
5232 inkscape:connector-curvature="0"
5233 id="R_IDH3" /><text
5234 style="font-size:10px;font-family:Calibri"
5235 id="text1410"
5236 class="st17 st18"
5237 x="789.9563"
5238 y="767.94257">NADH</text>
5239 <text
5240 style="font-size:10px;font-family:Calibri"
5241 id="text1412"
5242 class="st17 st18"
5243 x="814.58044"
5244 y="767.94257">+</text>
5245 <text
5246 style="font-size:10px;font-family:Calibri"
5247 id="text1414"
5248 class="st17 st18"
5249 x="789.9563"
5250 y="780.44257">H</text>
5251 <text
5252 style="font-size:10px;font-family:Calibri"
5253 id="text1416"
5254 class="st17 st18"
5255 x="796.18683"
5256 y="780.44257">+</text>
5257 <text
5258 style="font-size:10px;font-family:Calibri"
5259 id="text1418"
5260 class="st17 st18"
5261 x="801.1673"
5262 y="780.44257">CO</text>
5263 <text
5264 style="font-size:6.09369993px;font-family:Calibri"
5265 id="text1420"
5266 class="st17 st26"
5267 x="813.03253"
5268 y="782.44257">2</text>
5269 <text
5270 style="font-size:10px;font-family:Calibri"
5271 id="text1422"
5272 class="st17 st18"
5273 x="509.7952"
5274 y="894.0257">NADH+H</text>
5275 <text
5276 style="font-size:10px;font-family:Calibri"
5277 id="text1424"
5278 class="st17 st18"
5279 x="489.20441"
5280 y="902.28931">NAD</text>
5281 <path
5282 style="fill:none;stroke:#000000;stroke-width:2.09549999"
5283 d="m 429.3,916.81855 c -7.3,-1.3 -7.3,-10.9 -7.3,-10.9 m 29.9,10.9 c -7.3,-1.3 -7.3,-10.9 -7.3,-10.9 m 32.8,10.9 c -7.3,-1.3 -7.3,-10.9 -7.3,-10.9 m 22.9,10.8 c 7.3,-1.3 7.3,-10.9 7.3,-10.9 m 76.2,10.9 -167.7,0 0,-187.3 34.9,0"
5284 class="st135"
5285 inkscape:label="ME2_ME3_1"
5286 inkscape:connector-curvature="0"
5287 id="R_ME2_ME3_1" /><path
5288 style="fill:none;stroke:#000000;stroke-width:1.87170005"
5289 d="m 424,906.71855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 22.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 25.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -31,-176.2 c 6.4,-2 6.4,-2 6.4,-2 l -6.6,-2.3 1.7,2.2 -1.5,2.1 z"
5290 class="st30"
5291 inkscape:label="ME2_ME3_1 f"
5292 inkscape:connector-curvature="0"
5293 id="F_ME2_ME3_1" /><text
5294 style="font-size:10px;font-family:Calibri"
5295 id="text1428"
5296 class="st17 st18"
5297 x="457.70239"
5298 y="898.8313">NADH</text>
5299 <text
5300 style="font-size:10px;font-family:Calibri"
5301 id="text1430"
5302 class="st17 st18"
5303 x="441.25998"
5304 y="898.8313">H</text>
5305 <text
5306 style="font-size:10px;font-family:Calibri"
5307 id="text1432"
5308 class="st17 st18"
5309 x="415.7493"
5310 y="898.8147">CO</text>
5311 <text
5312 style="font-size:6.09369993px;font-family:Calibri"
5313 id="text1434"
5314 class="st17 st26"
5315 x="427.6145"
5316 y="900.8147">2</text>
5317 <text
5318 style="font-size:10px;font-family:Calibri"
5319 id="text1436"
5320 class="st17 st18"
5321 x="503.78641"
5322 y="944.25116">NADP</text>
5323 <path
5324 style="fill:none;stroke:#000000;stroke-width:2.14289999"
5325 d="m 429.3,920.51855 c -7.3,1.4 -7.3,11.4 -7.3,11.4 m 29.9,-11.4 c -7.3,1.4 -7.3,11.4 -7.3,11.4 m 32.8,-11.4 c -7.3,1.4 -7.3,11.4 -7.3,11.4 m 38.1,-11.3 c 7.2,1.7 7.2,14.6 7.2,14.6 m 61.2,-14.6 -177,0 0,-199.5 42.5,0"
5326 class="st136"
5327 inkscape:label="ME2_ME3_2"
5328 inkscape:connector-curvature="0"
5329 id="R_ME2_ME3_2" /><path
5330 style="fill:none;stroke:#000000;stroke-width:1.87170005"
5331 d="m 424,930.01855 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m 22.5,0 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m 25.5,0 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m -31,-207 c 6.5,-1.8 6.5,-1.8 6.5,-1.8 l -6.5,-2.5 1.7,2.2 -1.7,2.1 z"
5332 class="st30"
5333 inkscape:label="ME2_ME3_2 f"
5334 inkscape:connector-curvature="0"
5335 id="F_ME2_ME3_2" /><text
5336 style="font-size:10px;font-family:Calibri"
5337 id="text1440"
5338 class="st17 st18"
5339 x="456.02231"
5340 y="944.76099">NADPH</text>
5341 <text
5342 style="font-size:10px;font-family:Calibri"
5343 id="text1442"
5344 class="st17 st18"
5345 x="440.8992"
5346 y="944.5813">H</text>
5347 <text
5348 style="font-size:10px;font-family:Calibri"
5349 id="text1444"
5350 class="st17 st18"
5351 x="415.7981"
5352 y="944.5813">CO</text>
5353 <text
5354 style="font-size:6.09369993px;font-family:Calibri"
5355 id="text1446"
5356 class="st17 st26"
5357 x="427.66339"
5358 y="946.5813">2</text>
5359 <path
5360 style="fill:none;stroke:#000000;stroke-width:2.10339999"
5361 d="m 615.9,579.61855 c 5.9,-1.5 5.4,-12.9 5.4,-12.9 m 15.5,12.5 c 5.9,-1.3 4.4,-12.5 4.4,-12.5 m 14,12.5 -72.4,-0.2 m 19.7,-0.3 c -5.9,1.4 -4.4,13.7 -4.4,13.7 m 1.3,-12.8 c 5.9,-1.5 5.4,-12.9 5.4,-12.9"
5362 class="st137"
5363 inkscape:label="IDH1"
5364 inkscape:connector-curvature="0"
5365 id="R_IDH1" /><text
5366 style="font-size:10px;font-family:Calibri"
5367 id="text1449"
5368 class="st17 st18"
5369 x="619.24744"
5370 y="558.70239">H</text>
5371 <path
5372 style="fill:none;stroke:#000000;stroke-width:2.18210006"
5373 d="m 327.8,483.61855 c 0,-27.3 0,-27.3 0,-27.3 m -0.4,15.6 c -1.1,-6 -11.6,-4.8 -11.6,-4.8"
5374 class="st14"
5375 inkscape:label="FH_2"
5376 inkscape:connector-curvature="0"
5377 id="R_FH_2" /><path
5378 style="fill:none;stroke:#000000;stroke-width:2.18210006"
5379 d="m 330.1,482.71855 c -2.2,7.3 -2.2,7.3 -2.2,7.3 l -2.2,-7.3 2.2,1.8 2.2,-1.8 z"
5380 class="st14"
5381 inkscape:label="FH_2 f"
5382 inkscape:connector-curvature="0"
5383 id="F_FH_2" /><path
5384 style="fill:none;stroke:#000000;stroke-width:2.18210006"
5385 d="m 329.9,456.91855 c -2.2,-7.3 -2.2,-7.3 -2.2,-7.3 l -2.2,7.3 2.2,-1.8 2.2,1.8 z m -14.7,12 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z"
5386 class="st14"
5387 inkscape:label="FH_2 b"
5388 inkscape:connector-curvature="0"
5389 id="B_FH_2" /><text
5390 style="font-size:10px;font-family:Calibri"
5391 id="text1454"
5392 class="st17 st18"
5393 x="287.3587"
5394 y="527.83325">NAD</text>
5395 <text
5396 style="font-size:10px;font-family:Calibri"
5397 id="text1456"
5398 class="st17 st18"
5399 x="271.14529"
5400 y="544.677">NADH</text>
5401 <text
5402 style="font-size:10px;font-family:Calibri"
5403 id="text1458"
5404 class="st17 st18"
5405 x="295.76929"
5406 y="544.677">+</text>
5407 <text
5408 style="font-size:10px;font-family:Calibri"
5409 id="text1460"
5410 class="st17 st18"
5411 x="300.74979"
5412 y="544.677">H</text>
5413 <text
5414 style="font-size:16px;font-family:Calibri-Bold"
5415 id="text1462"
5416 class="st15 st16"
5417 x="429.36963"
5418 y="1131.9838">Q</text>
5419 <text
5420 style="font-size:16px;font-family:Calibri-Bold"
5421 id="text1464"
5422 class="st15 st16"
5423 x="350.36279"
5424 y="1132.7025">NADH</text>
5425 <text
5426 style="font-size:16px;font-family:Calibri-Bold"
5427 id="text1466"
5428 class="st15 st16"
5429 x="457.80908"
5430 y="1199.7504">4 H</text>
5431 <path
5432 style="fill:none;stroke:#000000;stroke-width:2.06859994"
5433 d="m 474.1998,1181.2711 -2.8,5.9 -2,-6.1 2.3,1.6 2.5,-1.4 z m 12.4,-39.3 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m 29.4,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z"
5434 class="st138"
5435 inkscape:label="Complex1ROS f"
5436 inkscape:connector-curvature="0"
5437 id="F_Complex1ROS" /><path
5438 style="fill:none;stroke:#000000;stroke-width:2.06859994"
5439 d="m 761.84776,1178.6878 -2.8,5.9 -2,-6.1 2.3,1.6 z m 27.25948,-37.9976 -2.8,-5.9 -2,6.1 2.3,-1.6 z m 52.82373,-0.1976 -2.8,-5.9 -2,6.1 2.3,-1.6 z"
5440 class="st138"
5441 inkscape:label="Complex3 f"
5442 inkscape:connector-curvature="0"
5443 id="F_Complex3"
5444 sodipodi:nodetypes="ccccccccccccccc" /><path
5445 style="fill:none;stroke:#000000;stroke-width:2.06859994"
5446 d="m 1050.1,1177.9186 -2.8,5.9 -2,-6.1 2.3,1.6 2.5,-1.4 z m 96.4,-35.6 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m -72,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z"
5447 class="st138"
5448 inkscape:label="Complex4 f"
5449 inkscape:connector-curvature="0"
5450 id="F_Complex4" /><text
5451 style="font-size:16px;font-family:Calibri-Bold"
5452 id="text1471"
5453 class="st15 st16"
5454 x="1186.5951"
5455 y="1132.6877">ADP</text>
5456 <text
5457 style="font-size:16px;font-family:Calibri-Bold"
5458 id="text1473"
5459 class="st15 st16"
5460 x="1258.2738"
5461 y="1131.0793">ATP</text>
5462 <text
5463 style="font-size:16px;font-family:Calibri-Bold"
5464 id="text1475"
5465 class="st15 st16"
5466 x="1288.1302"
5467 y="1131.2004">2 H</text>
5468 <text
5469 style="font-size:9.75px;font-family:Calibri-Bold"
5470 id="text1477"
5471 class="st15 st40"
5472 x="1309.9506"
5473 y="1134.3997">2</text>
5474 <text
5475 style="font-size:16px;font-family:Calibri-Bold"
5476 id="text1479"
5477 class="st15 st16"
5478 x="1314.8929"
5479 y="1131.2004">O</text>
5480 <text
5481 style="font-size:16px;font-family:Calibri-Bold"
5482 id="text1481"
5483 class="st15 st16"
5484 x="1224.5297"
5485 y="1132.1653">Pi</text>
5486 <text
5487 style="font-size:16px;font-family:Calibri-Bold"
5488 id="text1483"
5489 class="st15 st16"
5490 x="1234.349"
5491 y="1192.5237">4 H</text>
5492 <text
5493 style="font-size:16px;font-family:Calibri-Bold"
5494 id="text1485"
5495 class="st15 st16"
5496 x="1337.7094"
5497 y="1131.2004">4 H</text>
5498 <path
5499 style="fill:none;stroke:#000000;stroke-width:1.11870003"
5500 d="m 1310.4,1155.6186 0,-13.8 m -106.2,-2 0,16.2 142.6,0 0,-16.2 m -116.3,-0.5 0,16.2 m 43.9,0.1 0,-13.8 m -29.7,13.8 0,25.4"
5501 class="st139"
5502 inkscape:label="ATPsynthase "
5503 inkscape:connector-curvature="0"
5504 id="R_ATPsynthase" /><path
5505 style="fill:none;stroke:#000000;stroke-width:2.06859994"
5506 d="m 1313.3,1141.9186 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m 36,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m -72,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z"
5507 class="st138"
5508 inkscape:label="ATPsynthase f"
5509 inkscape:connector-curvature="0"
5510 id="F_ATPsynthase" /><text
5511 style="font-size:16px;font-family:Calibri-Bold"
5512 id="text1495"
5513 class="st15 st16"
5514 x="177.9417"
5515 y="839.77655">AKG</text>
5516 <text
5517 style="font-size:16px;font-family:Calibri-Bold"
5518 id="text1497"
5519 class="st15 st16"
5520 x="286.39868"
5521 y="840.57635">AKG</text>
5522 <path
5523 style="fill:none;stroke:#000000;stroke-width:2.82299995"
5524 d="m 275.8,835.31855 -60.2,-0.3 m 44.6,0.3 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -26.7,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7"
5525 class="st45"
5526 inkscape:label="SLC25A11"
5527 inkscape:connector-curvature="0"
5528 id="R_SLC25A11" /><path
5529 style="fill:none;stroke:#000000;stroke-width:2.32780004"
5530 d="m 267.4,821.81855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 l 0,0 z"
5531 class="st140"
5532 inkscape:label="SLC25A11 b"
5533 inkscape:connector-curvature="0"
5534 id="B_SLC25A11" /><text
5535 style="font-size:14px;font-family:Calibri-Bold"
5536 id="text1501"
5537 class="st15 st38"
5538 x="258.91681"
5539 y="813.65851">Mal</text>
5540 <text
5541 style="font-size:14px;font-family:Calibri-Bold"
5542 id="text1503"
5543 class="st15 st38"
5544 x="218.61449"
5545 y="814.12427">Mal</text>
5546 <path
5547 style="fill:none;stroke:#000000;stroke-width:2.35560012"
5548 d="m 233.9,824.21855 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 40.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
5549 class="st46"
5550 inkscape:label="SLC25A11 f"
5551 inkscape:connector-curvature="0"
5552 id="F_SLC25A11" /><text
5553 style="font-size:10px;font-family:Calibri"
5554 id="text1506"
5555 class="st17 st18"
5556 x="1286.9183"
5557 y="796.95239">HCO</text>
5558 <text
5559 style="font-size:6.09369993px;font-family:Calibri"
5560 id="text1508"
5561 class="st17 st26"
5562 x="1305.014"
5563 y="798.95239">3</text>
5564 <text
5565 style="font-size:6.09369993px;font-family:Calibri"
5566 id="text1510"
5567 class="st17 st26"
5568 x="1308.1029"
5569 y="791.45239">-</text>
5570 <text
5571 style="font-size:10px;font-family:Calibri"
5572 id="text1512"
5573 class="st17 st18"
5574 x="1261.7601"
5575 y="797.07349">2 ATP</text>
5576 <text
5577 style="font-size:10px;font-family:Calibri"
5578 id="text1514"
5579 class="st17 st18"
5580 x="1312.8011"
5581 y="797.28931">H</text>
5582 <text
5583 style="font-size:10px;font-family:Calibri"
5584 id="text1516"
5585 class="st17 st18"
5586 x="1215.6556"
5587 y="796.61255">2 ADP</text>
5588 <text
5589 style="font-size:10px;font-family:Calibri"
5590 id="text1518"
5591 class="st17 st18"
5592 x="1247.1156"
5593 y="797.24536">Pi</text>
5594 <path
5595 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5596 d="m 1198.1,755.61855 c 6.9,-1.7 6.9,-1.7 6.9,-1.7 l -7,-1.5 1.8,1.6 -1.7,1.6 z m -6.3,-8.1 c -1.9,-7.4 -1.9,-7.4 -1.9,-7.4 l -2.4,7.2 2.2,-1.8 2.1,2 z"
5597 class="st73"
5598 inkscape:label="OTC_LEFTY1 f"
5599 inkscape:connector-curvature="0"
5600 id="F_OTC_LEFTY1" /><text
5601 style="font-size:10px;font-family:Calibri"
5602 id="text1521"
5603 class="st17 st18"
5604 x="1207.1527"
5605 y="756.75415">Pi</text>
5606 <path
5607 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5608 d="m 1205.4,705.01855 c 5.4,1.6 5.4,1.6 5.4,1.6 l -5.8,1.7 1.6,-1.6 -1.2,-1.7 z m 0,-12 c 5.4,1.6 5.4,1.6 5.4,1.6 l -5.8,1.7 1.6,-1.6 -1.2,-1.7 z m -12.9,-39.4 c -2.6,-7.2 -2.6,-7.2 -2.6,-7.2 l -1.7,7.4 2,-2 2.3,1.8 z"
5609 class="st73"
5610 inkscape:label="SLC25A15_SLC25A2_1 f"
5611 inkscape:connector-curvature="0"
5612 id="F_SLC25A15_SLC25A2_1" /><path
5613 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5614 d="m 1165.5,612.21855 c -6.9,1.7 -6.9,1.7 -6.9,1.7 l 7,1.5 -1.8,-1.6 1.7,-1.6 z m 14.8,-3.2 c -0.8,-7.6 -0.8,-7.6 -0.8,-7.6 l -3.4,6.8 2.5,-1.4 1.7,2.2 z"
5615 class="st73"
5616 inkscape:label="ASS1 f"
5617 inkscape:connector-curvature="0"
5618 id="F_ASS1" /><path
5619 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5620 d="m 1260.6,601.11855 c 6.9,-1.7 6.9,-1.7 6.9,-1.7 l -7,-1.5 1.8,1.6 -1.7,1.6 z m -14.1,15.4 c 0.8,7.6 0.8,7.6 0.8,7.6 l 3.4,-6.8 -2.4,1.4 -1.8,-2.2 z"
5621 class="st73"
5622 inkscape:label="ARG2_ARG1 f"
5623 inkscape:connector-curvature="0"
5624 id="F_ARG2_ARG1" /><path
5625 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5626 d="m 1307.9,604.11855 c 6.9,-1.7 6.9,-1.7 6.9,-1.7 l -7,-1.5 1.8,1.6 -1.7,1.6 z m -8.3,-7.4 c -1.9,-7.4 -1.9,-7.4 -1.9,-7.4 l -2.4,7.2 2.2,-1.8 2.1,2 z"
5627 class="st73"
5628 inkscape:label="OGDH_ODC1_OGDHL f"
5629 inkscape:connector-curvature="0"
5630 id="F_OGDH_ODC1_OGDHL" /><path
5631 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5632 d="m 1410.9,573.21855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 19,-6.5 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z"
5633 class="st73"
5634 inkscape:label="arginineAmidinohydrolase"
5635 inkscape:connector-curvature="0"
5636 id="F_arginineAmidinohydrolase" /><path
5637 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5638 d="m 1226.5,773.71855 -7.3,2.2 7.3,2.2 -1.8,-2.2 1.8,-2.2 z m 6.9,9 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 15.5,0.5 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z"
5639 class="st73"
5640 inkscape:label="CPS1"
5641 inkscape:connector-curvature="0"
5642 id="F_CPS1" /><path
5643 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5644 d="m 1424.1,609.91855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 7.6,-4.7 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z"
5645 class="st73"
5646 inkscape:label="PYCRL_PYCR2_PYCR1_LEFTY1_1 f"
5647 inkscape:connector-curvature="0"
5648 id="F_PYCRL_PYCR2_PYCR1_LEFTY1_1" /><path
5649 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5650 d="m 1427.1,638.71855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 25.3,-21.9 c -1.8,-7.4 -1.8,-7.4 -1.8,-7.4 l -2.5,7.2 2.2,-1.7 2.1,1.9 z"
5651 class="st73"
5652 inkscape:label="PYCRL_PYCR2_PYCR1_LEFTY1_2 f"
5653 inkscape:connector-curvature="0"
5654 id="F_PYCRL_PYCR2_PYCR1_LEFTY1_2" /><path
5655 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5656 d="m 389.7,362.01855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
5657 class="st73"
5658 inkscape:connector-curvature="0"
5659 id="path2280" /><path
5660 style="fill:none;stroke:#000000;stroke-width:2.29760003"
5661 d="m 376.4,277.61855 c 1.4,5.3 17.3,5.1 17.3,5.1 m -78.9,-8.4 c 36.8,-1.5 60.9,1.7 60.9,1.7 m 0.6,47.2 -0.1,-55.9 m -15.7,21.2 c 9.7,-2.9 16,3.2 16,3.2"
5662 class="st79"
5663 inkscape:connector-curvature="0"
5664 id="R_SHMT1" /><path
5665 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5666 d="m 314.9,275.71855 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z m 63.2,-8.2 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -14.8,22 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
5667 class="st73"
5668 inkscape:connector-curvature="0"
5669 id="F_SHMT1" /><text
5670 style="font-size:9.99962234px;font-family:Calibri"
5671 id="text1534"
5672 class="st17 st18"
5673 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
5674 x="333.75421"
5675 y="294.88434">H</text>
5676 <text
5677 style="font-size:6.09346962px;font-family:Calibri"
5678 id="text1536"
5679 class="st17 st26"
5680 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
5681 x="339.98471"
5682 y="296.88437">2</text>
5683 <text
5684 style="font-size:9.99962234px;font-family:Calibri"
5685 id="text1538"
5686 class="st17 st18"
5687 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
5688 x="343.07361"
5689 y="294.8844">O</text>
5690 <path
5691 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5692 d="m 401.7,328.31855 c 1.3,-7 1.3,-7 1.3,-7 l 1.9,6.9 -1.7,-1.7 -1.5,1.8 z m 10.4,8.6 c 6.3,2.2 6.3,2.2 6.3,2.2 l -6.5,1.7 1.7,-1.9 -1.5,-2 z"
5693 class="st73"
5694 inkscape:label="SDS_SDSL_SRR"
5695 inkscape:connector-curvature="0"
5696 id="F_SDS_SDSL_SRR" /><path
5697 style="fill:none;stroke:#000000;stroke-width:2.18140006"
5698 d="m 453.8,622.71855 0,19.5 -67.5,0 m 23.1,-11 c -2.7,7 3.5,11.5 3.5,11.5 m 10.9,-0.1 c 5.4,-0.9 4.9,-10.3 4.9,-10.3"
5699 class="st141"
5700 inkscape:label="NIT2"
5701 inkscape:connector-curvature="0"
5702 id="R_NIT2" /><text
5703 style="font-size:10px;font-family:Calibri"
5704 id="text1542"
5705 class="st17 st18"
5706 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
5707 x="301.05325"
5708 y="582.61121">Glu</text>
5709 <text
5710 style="font-size:9.99962234px;font-family:Calibri"
5711 id="text1544"
5712 class="st17 st18"
5713 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
5714 x="288.98755"
5715 y="601.8775">AKG</text>
5716 <path
5717 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5718 d="m 327.2,600.61855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m -7,-4.3 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
5719 class="st73"
5720 inkscape:label="GOT1_GOT2_GOT1L1_2 bb"
5721 inkscape:connector-curvature="0"
5722 id="B_GOT1_GOT2_GOT1L1_2" /><path
5723 style="fill:none;stroke:#000000;stroke-width:2.06480002"
5724 d="m 329.3,603.91855 -0.2,-29.4 m -12.3,8.1 c 7.6,-2.9 12.6,3.3 12.6,3.3 m 0,3.4 c -0.9,5.5 -11.2,5.2 -11.2,5.2"
5725 class="st142"
5726 inkscape:label="GOT1_GOT2_GOT1L1_2"
5727 inkscape:connector-curvature="0"
5728 id="R_GOT1_GOT2_GOT1L1_2" /><path
5729 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5730 d="m 331,575.81855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -10.2,7.7 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
5731 class="st73"
5732 inkscape:label="GOT1_GOT2_GOT1L1_2 f"
5733 inkscape:connector-curvature="0"
5734 id="F_GOT1_GOT2_GOT1L1_2" /><text
5735 style="font-size:10px;font-family:Calibri"
5736 id="text1549"
5737 class="st17 st18"
5738 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
5739 x="302.24371"
5740 y="760.4939">Glu</text>
5741 <text
5742 style="font-size:9.99962234px;font-family:Calibri"
5743 id="text1551"
5744 class="st17 st18"
5745 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
5746 x="288.6842"
5747 y="751.92932">AKG</text>
5748 <path
5749 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5750 d="m 328.8,764.61855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m -8,-4.3 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
5751 class="st73"
5752 inkscape:label="GOT2_GOT1L1_1 b"
5753 inkscape:connector-curvature="0"
5754 id="B_GOT2_GOT1L1_1" /><path
5755 style="fill:none;stroke:#000000;stroke-width:2.06480002"
5756 d="m 330.9,768.01855 -0.2,-29.4 m -13.3,8.1 c 8.1,-2.9 13.4,3.3 13.4,3.3 m -0.1,3.3 c -1,5.4 -11.9,5.2 -11.9,5.2"
5757 class="st142"
5758 inkscape:label="GOT2_GOT1L1_1"
5759 inkscape:connector-curvature="0"
5760 id="R_GOT2_GOT1L1_1" /><path
5761 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5762 d="m 332.6,739.81855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -11.2,7.7 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
5763 class="st73"
5764 inkscape:label="GOT2_GOT1L1_1 f"
5765 inkscape:connector-curvature="0"
5766 id="F_GOT2_GOT1L1_1" /><path
5767 style="fill:none;stroke:#000000;stroke-width:2.5236001"
5768 d="m 270.8,636.91855 c -1.4,6.1 -13.6,4.6 -13.6,4.6 m 58.1,-13.7 -44.2,0 0,24.1"
5769 class="st143"
5770 inkscape:label="FH_3"
5771 inkscape:connector-curvature="0"
5772 id="R_FH_3" /><path
5773 style="fill:none;stroke:#000000;stroke-width:1.87170005"
5774 d="m 203.3,605.11855 c -1.5,-5.1 -1.5,-5.1 -1.5,-5.1 l -1.8,5.5 1.7,-1.5 1.6,1.1 z m -25.5,6.7 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z"
5775 class="st30"
5776 inkscape:connector-curvature="0"
5777 id="F_ASNS" /><path
5778 style="fill:none;stroke:#000000;stroke-width:1.87170005"
5779 d="m 306.6,623.91855 c 6.3,-2.2 6.3,-2.2 6.3,-2.2 l -6.5,-1.7 1.7,1.9 -1.5,2 z m -87.9,7 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
5780 class="st30"
5781 inkscape:connector-curvature="0"
5782 id="path2462" /><path
5783 style="fill:none;stroke:#000000;stroke-width:2.5697"
5784 d="m 174.6,621.51855 134,0.1 m -89.1,9.8 c 2.6,-5.3 -3.5,-9.1 -3.5,-9.1 m -23.9,-0.1 c -5,1.5 -4.6,13.1 -4.6,13.1"
5785 class="st144"
5786 inkscape:connector-curvature="0"
5787 id="R_ASRGL1_ASPG" /><path
5788 style="fill:none;stroke:#000000;stroke-width:2.18210006"
5789 d="m 327.8,536.41855 c -1.1,6 -11.6,4.8 -11.6,4.8 m 11.6,5.6 c 0,-30.5 0,-30.5 0,-30.5 m 0,14.1 c -1.1,-6 -11.6,-4.8 -11.6,-4.8"
5790 class="st14"
5791 inkscape:label="MDH1_MDH1B "
5792 inkscape:connector-curvature="0"
5793 id="R_MDH1_MDH1B" /><path
5794 style="fill:none;stroke:#000000;stroke-width:2.18210006"
5795 d="m 315.6,539.51855 c -4.9,2 -4.9,2 -4.9,2 l 5.6,1.3 -1.7,-1.6 1,-1.7 z m 14.6,6.2 c -2.2,7.3 -2.2,7.3 -2.2,7.3 l -2.2,-7.3 2.2,1.8 2.2,-1.8 z"
5796 class="st14"
5797 inkscape:label="MDH1_MDH1B f"
5798 inkscape:connector-curvature="0"
5799 id="F_MDH1_MDH1B" /><path
5800 style="fill:none;stroke:#000000;stroke-width:2.18210006"
5801 d="m 329.9,517.91855 c -2.2,-7.3 -2.2,-7.3 -2.2,-7.3 l -2.2,7.3 2.2,-1.8 2.2,1.8 z m -14.3,9.5 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z"
5802 class="st14"
5803 inkscape:label="MDH1_MDH1B b"
5804 inkscape:connector-curvature="0"
5805 id="B_MDH1_MDH1B" /><path
5806 style="fill:none;stroke:#000000;stroke-width:2.09949994"
5807 d="m 853.3,730.91855 c 1.7,-6.9 1.7,-6.9 1.7,-6.9 l 1.5,7 -1.6,-1.7 -1.6,1.6 z m -94.9,7.7 c -7.3,2.3 -7.3,2.3 -7.3,2.3 l 7.3,2 -1.9,-2.1 1.9,-2.2 z"
5808 class="st73"
5809 inkscape:label="GLUD1_GLUD2_1 F"
5810 inkscape:connector-curvature="0"
5811 id="F_GLUD1_GLUD2_1" /><text
5812 style="font-size:10px;font-family:Calibri"
5813 id="text1564"
5814 class="st17 st18"
5815 x="843.83331"
5816 y="243.37524">Asp</text>
5817 <text
5818 style="font-size:16px;font-family:Calibri-Bold"
5819 id="text1566"
5820 class="st15 st16"
5821 x="1104.5219"
5822 y="229.47775">AMP</text>
5823 <text
5824 style="font-size:10px;font-family:Calibri"
5825 id="text1568"
5826 class="st17 st18"
5827 x="1032.9047"
5828 y="239.12524">GTP</text>
5829 <text
5830 style="font-size:10px;font-family:Calibri"
5831 id="text1570"
5832 class="st17 st18"
5833 x="1056.3265"
5834 y="238.95825">Asp</text>
5835 <text
5836 style="font-size:10px;font-family:Calibri"
5837 id="text1572"
5838 class="st17 st18"
5839 x="1070.4886"
5840 y="207.11935">Fum</text>
5841 <text
5842 style="font-size:10px;font-family:Calibri"
5843 id="text1574"
5844 class="st17 st18"
5845 x="1038.6117"
5846 y="207.13495">GDP</text>
5847 <text
5848 style="font-size:16px;font-family:Calibri-Bold"
5849 id="text1576"
5850 class="st15 st16"
5851 x="1190.1205"
5852 y="274.58914">GMP</text>
5853 <text
5854 style="font-size:10px;font-family:Calibri"
5855 id="text1578"
5856 class="st17 st18"
5857 x="1022.7562"
5858 y="251.87625">NAD</text>
5859 <text
5860 style="font-size:10px;font-family:Calibri"
5861 id="text1580"
5862 class="st17 st18"
5863 x="1044.2269"
5864 y="251.96504">H</text>
5865 <text
5866 style="font-size:6.09369993px;font-family:Calibri"
5867 id="text1582"
5868 class="st17 st26"
5869 x="1050.4574"
5870 y="253.96504">2</text>
5871 <text
5872 style="font-size:10px;font-family:Calibri"
5873 id="text1584"
5874 class="st17 st18"
5875 x="1053.5463"
5876 y="251.96504">O</text>
5877 <text
5878 style="font-size:10px;font-family:Calibri"
5879 id="text1586"
5880 class="st17 st18"
5881 x="1096.4867"
5882 y="251.55885">NADH</text>
5883 <text
5884 style="font-size:10px;font-family:Calibri"
5885 id="text1588"
5886 class="st17 st18"
5887 x="1124.9867"
5888 y="251.55885">H</text>
5889 <text
5890 style="font-size:10px;font-family:Calibri"
5891 id="text1590"
5892 class="st17 st18"
5893 x="1136.9867"
5894 y="251.55885">AMP</text>
5895 <text
5896 style="font-size:10px;font-family:Calibri"
5897 id="text1592"
5898 class="st17 st18"
5899 x="1062.2269"
5900 y="251.96504">ATP</text>
5901 <text
5902 style="font-size:10px;font-family:Calibri"
5903 id="text1594"
5904 class="st17 st18"
5905 x="1078.7269"
5906 y="251.96504">NH</text>
5907 <text
5908 style="font-size:6.09369993px;font-family:Calibri"
5909 id="text1596"
5910 class="st17 st26"
5911 x="1091.4125"
5912 y="253.96504">3</text>
5913 <path
5914 style="fill:#786721;stroke:#000000;stroke-width:2.5"
5915 d="m 1165.6,258.31855 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z m 7.2,8.5 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -25.2,-8.5 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z m -16.5,0 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z m -21,0 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z"
5916 class="st145"
5917 inkscape:label="GMPS f"
5918 inkscape:connector-curvature="0"
5919 id="F_GMPS" /><text
5920 style="font-size:10px;font-family:Calibri"
5921 id="text1599"
5922 class="st17 st18"
5923 x="1159.4867"
5924 y="251.55885">PPi</text>
5925 <path
5926 style="fill:none;stroke:#000000;stroke-width:1.45089996"
5927 d="m 1017,234.51855 0,30 156.7,0 m -13.1,-0.1 c 4.8,-1 3,-7.4 3,-7.4 m -76.3,-1.9 c -1.5,6.1 4.8,9.3 4.8,9.3 m -24.3,-9.3 c -1.5,6.1 4.8,9.3 4.8,9.3 m 70,0 c 4.8,-1 3,-7.4 3,-7.4 m -19.5,7.4 c 4.8,-1 3,-7.4 3,-7.4 m -79.3,-1.9 c -1.5,6.1 4.8,9.3 4.8,9.3 m -19.7,-9.3 c -1.5,6.1 4.8,9.3 4.8,9.3 m 65.4,0 c 4.8,-1 3,-7.4 3,-7.4"
5928 class="st146"
5929 inkscape:label="GMPS"
5930 inkscape:connector-curvature="0"
5931 id="R_GMPS" /><text
5932 style="font-size:10px;font-family:Calibri"
5933 id="text1602"
5934 class="st17 st18"
5935 x="1089.4623"
5936 y="295.44165">NADPH</text>
5937 <path
5938 style="fill:none;stroke:#000000;stroke-width:2.5"
5939 d="m 1126.6,282.21855 c -1.6,4.7 -1.6,4.7 -1.6,4.7 l -2.4,-4.6 2.1,1.1 1.9,-1.2 z m -18,0 c -1.6,4.7 -1.6,4.7 -1.6,4.7 l -2.4,-4.6 2.1,1.1 1.9,-1.2 z m 64,-4.2 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.3,-1.9 1.9,2.1 -1.8,2.2 z"
5940 class="st22"
5941 inkscape:connector-curvature="0"
5942 id="path2738" /><text
5943 style="font-size:10px;font-family:Calibri"
5944 id="text1605"
5945 class="st17 st18"
5946 x="1122.9066"
5947 y="295.62234">H</text>
5948 <text
5949 style="font-size:10px;font-family:Calibri"
5950 id="text1607"
5951 class="st17 st18"
5952 x="1045.0922"
5953 y="295.91525">NADP</text>
5954 <text
5955 style="font-size:10px;font-family:Calibri"
5956 id="text1609"
5957 class="st17 st18"
5958 x="1070.9701"
5959 y="295.55396">NH</text>
5960 <text
5961 style="font-size:6.09369993px;font-family:Calibri"
5962 id="text1611"
5963 class="st17 st26"
5964 x="1083.6556"
5965 y="297.55396">3</text>
5966 <path
5967 style="fill:none;stroke:#000000;stroke-width:1.7529"
5968 d="m 1076.8,287.31855 c -1.5,-7.6 4.8,-11.6 4.8,-11.6 m -24.2,11.6 c -1.5,-7.6 4.8,-11.6 4.8,-11.6 m 59.4,0.1 c 4.8,0.9 3,6.9 3,6.9 m -21,-6.9 c 4.8,0.9 3,6.9 3,6.9 m -95.6,-48.5 0,41.6 162.2,0"
5969 class="st147"
5970 inkscape:label="GMPR2_GMPR"
5971 inkscape:connector-curvature="0"
5972 id="R_GMPR2_GMPR" /><path
5973 style="fill:none;stroke:#000000;stroke-width:1.92519999"
5974 d="m 1257.8,269.81855 c -24.9,0 -24.9,0 -24.9,0 m 16.5,9.6 c 2.4,-5.9 -3.6,-9.5 -3.6,-9.5 m -2.6,0.1 c -5,0.9 -4.4,9.3 -4.4,9.3"
5975 class="st148"
5976 inkscape:label="GUK1_1"
5977 inkscape:connector-curvature="0"
5978 id="R_GUK1_1" /><text
5979 style="font-size:10px;font-family:Calibri"
5980 id="text1615"
5981 class="st17 st18"
5982 x="1305.1234"
5983 y="296.55396">H</text>
5984 <text
5985 style="font-size:6.09369993px;font-family:Calibri"
5986 id="text1617"
5987 class="st17 st26"
5988 x="1311.3539"
5989 y="298.55396">2</text>
5990 <text
5991 style="font-size:10px;font-family:Calibri"
5992 id="text1619"
5993 class="st17 st18"
5994 x="1314.4427"
5995 y="296.55396">O</text>
5996 <path
5997 style="fill:none;stroke:#000000;stroke-width:1.89830005"
5998 d="m 1324,269.41855 c -24.2,0 -24.2,0 -24.2,0 m 15.6,11.1 c 2.4,-6.8 -3.6,-11 -3.6,-11"
5999 class="st149"
6000 inkscape:label="RRM2B_TXN_RRM1_RRM2B_1"
6001 inkscape:connector-curvature="0"
6002 id="R_RRM2B_TXN_RRM1_RRM2B_1" /><text
6003 style="font-size:16px;font-family:Calibri-Bold"
6004 id="text1622"
6005 class="st15 st16"
6006 x="1336.0267"
6007 y="274.81174">dGDP</text>
6008 <text
6009 style="font-size:16px;font-family:Calibri-Bold"
6010 id="text1624"
6011 class="st15 st16"
6012 x="1189.1234"
6013 y="226.54515">ADP</text>
6014 <text
6015 style="font-size:10px;font-family:Calibri"
6016 id="text1626"
6017 class="st17 st18"
6018 x="1144.3539"
6019 y="205.21504">ATP</text>
6020 <text
6021 style="font-size:10px;font-family:Calibri"
6022 id="text1628"
6023 class="st17 st18"
6024 x="1162.7318"
6025 y="204.82245">ADP</text>
6026 <text
6027 style="font-size:10px;font-family:Calibri"
6028 id="text1630"
6029 class="st17 st18"
6030 x="1225.3851"
6031 y="248.99045">H</text>
6032 <text
6033 style="font-size:6.09369993px;font-family:Calibri"
6034 id="text1632"
6035 class="st17 st26"
6036 x="1231.6156"
6037 y="250.99045">2</text>
6038 <text
6039 style="font-size:10px;font-family:Calibri"
6040 id="text1634"
6041 class="st17 st18"
6042 x="1234.7035"
6043 y="248.99045">O</text>
6044 <path
6045 style="fill:none;stroke:#000000;stroke-width:1.77349997"
6046 d="m 1239.9,223.41855 c -21.1,0 -21.1,0 -21.1,0 m 12.6,11.4 c 2.4,-7 -3.6,-11.3 -3.6,-11.3"
6047 class="st150"
6048 inkscape:label="RRM2B_TXN_RRM1_RRM2B_2"
6049 inkscape:connector-curvature="0"
6050 id="R_RRM2B_TXN_RRM1_RRM2B_2" /><text
6051 style="font-size:16px;font-family:Calibri-Bold"
6052 id="text1637"
6053 class="st15 st16"
6054 x="1251.2035"
6055 y="225.97145">dADP</text>
6056 <text
6057 style="font-size:10px;font-family:Calibri"
6058 id="text1639"
6059 class="st17 st18"
6060 x="989.38702"
6061 y="354.02756">ATP</text>
6062 <text
6063 style="font-size:10px;font-family:Calibri"
6064 id="text1641"
6065 class="st17 st18"
6066 x="1006.057"
6067 y="353.84204">ADP</text>
6068 <path
6069 style="fill:none;stroke:#000000;stroke-width:1.82930005"
6070 d="m 1014.9,334.41855 c 7.4,-1.9 7.4,-1.9 7.4,-1.9 l -7.2,-2.4 1.8,2.2 -2,2.1 z m -5.5,5.8 c 2.4,5.1 2.4,5.1 2.4,5.1 l 2,-5.2 -2.1,1.3 -2.3,-1.2 z"
6071 class="st109"
6072 inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3 b"
6073 inkscape:connector-curvature="0"
6074 id="B_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3" /><path
6075 style="fill:none;stroke:#000000;stroke-width:1.55369997"
6076 d="m 1004.5,332.21855 c -4.9,1.2 -3.1,9.2 -3.1,9.2 m 10.5,0.8 c 1.6,-6.3 -4.9,-9.6 -4.9,-9.6 m 10.9,-0.3 -25.4,-0.2"
6077 class="st151"
6078 inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3"
6079 inkscape:connector-curvature="0"
6080 id="R_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3" /><text
6081 style="font-size:10px;font-family:Calibri"
6082 id="text1645"
6083 class="st17 st18"
6084 x="484.89191"
6085 y="128.75026">ADP</text>
6086 <text
6087 style="font-size:16px;font-family:Calibri-Bold"
6088 id="text1647"
6089 class="st15 st16"
6090 x="448.1004"
6091 y="156.49535">G6P</text>
6092 <text
6093 style="font-size:16px;font-family:Calibri-Bold"
6094 id="text1649"
6095 class="st15 st16"
6096 x="450.83908"
6097 y="90.690155">Glc</text>
6098 <path
6099 style="fill:none;stroke:#000000;stroke-width:2.18210006"
6100 d="m 465.3,424.91855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z m 11.2,-16.2 c 1.6,0.7 3.3,1.4 4.9,2 -1.9,0.4 -3.8,0.8 -5.6,1.3 0.6,-0.5 1.1,-1 1.7,-1.6 -0.4,-0.5 -0.7,-1.1 -1,-1.7 l 0,0 z"
6101 class="st14"
6102 inkscape:label="CRISP3_PGK1_MIA3_PGK2 f"
6103 inkscape:connector-curvature="0"
6104 id="F_CRISP3_PGK1_MIA3_PGK2" /><path
6105 style="fill:none;stroke:#000000;stroke-width:1.87170005"
6106 d="m 447.4,607.61855 7.3,2.2 -7.3,2.2 1.8,-2.2 -1.8,-2.2 z m -10.6,-6.6 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6107 class="st30"
6108 inkscape:label="LDH b"
6109 inkscape:connector-curvature="0"
6110 id="B_LDH" /><path
6111 style="fill:none;stroke:#000000;stroke-width:1.82930005"
6112 d="m 861.8,126.21855 0,-11.3 30,0 m -20.8,-8.8 c -1.7,5.6 4.7,8.7 4.7,8.7 m 3.2,-0.2 c 4.9,-1.1 3.2,-8.9 3.2,-8.9"
6113 class="st109"
6114 inkscape:label="PFKP_PFKL_PFKM_3"
6115 inkscape:connector-curvature="0"
6116 id="R_PFKP_PFKL_PFKM_3" /><path
6117 style="fill:none;stroke:#000000;stroke-width:1.87170005"
6118 d="m 888.2,116.91855 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.2 1.8,2.2 -1.8,2.2 z m -6.9,-9.3 c 1.5,-4.3 1.5,-4.3 1.5,-4.3 l 1.4,4.7 -1.4,-1.3 -1.5,0.9 z"
6119 class="st30"
6120 inkscape:label="PFKP_PFKL_PFKM_3 b"
6121 inkscape:connector-curvature="0"
6122 id="B_PFKP_PFKL_PFKM_3" /><path
6123 style="fill:none;stroke:#000000;stroke-width:1.71169996"
6124 d="m 859.5,122.51855 c 2.1,6.2 2.1,6.2 2.1,6.2 l 2.1,-6.2 -2.1,1.5 -2.1,-1.5 z m 9.8,-14.9 c 1.5,-4.3 1.5,-4.3 1.5,-4.3 l 1.4,4.7 -1.4,-1.3 -1.5,0.9 z"
6125 class="st152"
6126 inkscape:label="PFKP_PFKL_PFKM_3 f"
6127 inkscape:connector-curvature="0"
6128 id="F_PFKP_PFKL_PFKM_3" /><path
6129 style="fill:none;stroke:#000000;stroke-width:1.74290001"
6130 d="m 491.3,814.71855 61.5,3.7 m 11.8,25.5 c -4.4,0.5 -8.8,-1.3 -11.3,-4.5 -2.5,-3.3 -2.7,-7.5 -0.6,-10.8 2.2,-3.4 6.4,-5.3 10.8,-5.1 m -9.8,29.2 c -3.7,-13.4 -3.5,-27.4 0.7,-40.9"
6131 class="st153"
6132 inkscape:label="CS"
6133 inkscape:connector-curvature="0"
6134 id="R_CS" /><path
6135 style="fill:none;stroke:#000000;stroke-width:1.63900006"
6136 d="m 662.5,768.41855 c 2.1,4.7 2.1,4.7 2.1,4.7 l 1,-5.3 -1.4,1.6 -1.7,-1 z m 37.5,-1.5 c 2.1,4.7 2.1,4.7 2.1,4.7 l 1,-5.3 -1.4,1.6 -1.7,-1 z m 9.6,-14.8 c 6.3,-1.4 6.3,-1.4 6.3,-1.4 l -4.4,4.1 0.4,-2 -2.3,-0.7 z m -26.1,17.8 c 2.1,4.7 2.1,4.7 2.1,4.7 l 1,-5.3 -1.4,1.6 -1.7,-1 z"
6137 class="st154"
6138 inkscape:label="IDH3 f"
6139 inkscape:connector-curvature="0"
6140 id="F_IDH3" /><path
6141 style="fill:none;stroke:#000000;stroke-width:1.81630003"
6142 d="m 640,727.51855 c -3.8,-4 -3.8,-4 -3.8,-4 l 1.6,6.8 0.4,-2.8 1.8,0 z m -6.5,12.6 c -6.3,1.4 -6.3,1.4 -6.3,1.4 l 4.4,-4.1 -0.4,2 2.3,0.7 z"
6143 class="st134"
6144 inkscape:label="IDH2 b"
6145 inkscape:connector-curvature="0"
6146 id="B_IDH2" /><path
6147 style="fill:none;stroke:#000000;stroke-width:1.63900006"
6148 d="m 661.1,725.61855 c 2.1,-4.7 2.1,-4.7 2.1,-4.7 l 1,5.3 -1.4,-1.6 -1.7,1 z m 38.1,1.5 c 2.1,-4.7 2.1,-4.7 2.1,-4.7 l 1,5.3 -1.4,-1.6 -1.7,1 z m -15.7,-3 c 2.1,-4.7 2.1,-4.7 2.1,-4.7 l 1,5.3 -1.4,-1.6 -1.7,1 z m 26.1,17.3 c 6.3,1.4 6.3,1.4 6.3,1.4 l -4.4,-4.1 0.4,2 -2.3,0.7 z"
6149 class="st154"
6150 inkscape:connector-curvature="0"
6151 id="path2385" /><path
6152 style="fill:none;stroke:#000000;stroke-width:1.81599998"
6153 d="m 775.5,787.91855 c 4.5,4.3 4.5,4.3 4.5,4.3 l -1.5,-6.1 -0.8,2.2 -2.2,-0.4 z m 7.8,-13.5 c 3.8,-1 3.8,-1 3.8,-1 l -2.8,3.2 0.3,-1.7 -1.3,-0.5 z"
6154 class="st55"
6155 inkscape:label="DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL f"
6156 inkscape:connector-curvature="0"
6157 id="F_DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL" /><path
6158 style="fill:none;stroke:#000000;stroke-width:1.81599998"
6159 d="m 551.9,886.51855 c -4,4 -4,4 -4,4 l 5.5,-0.9 -1.9,-1 0.4,-2.1 z m 9.4,-8.4 c -4.3,-4.3 -4.3,-4.3 -4.3,-4.3 l 1.3,6 0.8,-2.1 2.2,0.4 z"
6160 class="st55"
6161 inkscape:label="MDH2 f"
6162 inkscape:connector-curvature="0"
6163 id="F_MDH2" /><path
6164 style="fill:none;stroke:#000000;stroke-width:1.87170005"
6165 d="m 572.4,693.91855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -10.5,-159.2 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z"
6166 class="st30"
6167 inkscape:label="SLC25A1 f"
6168 inkscape:connector-curvature="0"
6169 id="F_SLC25A1" /><path
6170 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6171 d="m 561.5,781.41855 c -2.3,6.3 -2.3,6.3 -2.3,6.3 l -1.6,-6.5 1.9,1.7 2,-1.5 z m -16.4,-117.8 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z"
6172 class="st73"
6173 inkscape:label="SLC25A1 b"
6174 inkscape:connector-curvature="0"
6175 id="B_SLC25A1" /><path
6176 style="fill:none;stroke:#000000;stroke-width:2.5"
6177 d="m 639.9,566.81855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.1,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -16.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 50.9,14.5 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
6178 class="st22"
6179 inkscape:label="IDH1 f"
6180 inkscape:connector-curvature="0"
6181 id="F_IDH1" /><path
6182 style="fill:none;stroke:#000000;stroke-width:2.5"
6183 d="m 637.5,509.41855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -16.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.1,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 51.9,11.5 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
6184 class="st22"
6185 inkscape:label="ACLY f"
6186 inkscape:connector-curvature="0"
6187 id="F_ACLY" /><path
6188 style="fill:none;stroke:#000000;stroke-width:2.41549993"
6189 d="m 1094.7,430.01855 -120.1,-0.2 m 106.7,0.4 c -6,1.3 -5.5,10.6 -5.5,10.6 m -88,-10.9 c -6,1.3 -5.5,10.6 -5.5,10.6 m 48,-10.5 c -6,1.3 -5.5,10.6 -5.5,10.6 m 3.2,-10.2 c 5.9,-1.3 4.4,-11.9 4.4,-11.9 m 46.7,11.9 c 5.9,-1.3 4.4,-11.9 4.4,-11.9 m -93.9,11.4 c 5.9,-1.3 4.4,-11.9 4.4,-11.9 m 58.8,11.9 c 5.9,-1.3 4.4,-11.9 4.4,-11.9"
6190 class="st155"
6191 inkscape:label="OLAH_FASN "
6192 inkscape:connector-curvature="0"
6193 id="R_OLAH_FASN" /><text
6194 style="font-size:10px;font-family:Calibri"
6195 id="text1667"
6196 class="st17 st18"
6197 x="722.22681"
6198 y="501.87915">CoA</text>
6199 <path
6200 style="fill:none;stroke:#000000;stroke-width:1.96720004"
6201 d="m 740.8,519.01855 -25,-0.5 m 12.1,-0.2 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.3,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
6202 class="st156"
6203 inkscape:label="ACAT1_ACAT2"
6204 inkscape:connector-curvature="0"
6205 id="R_ACAT1_ACAT2" /><path
6206 style="fill:none;stroke:#000000;stroke-width:1.87170005"
6207 d="m 728.4,509.41855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 11.1,11.6 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z"
6208 class="st30"
6209 inkscape:label="ACAT1_ACAT2 f"
6210 inkscape:connector-curvature="0"
6211 id="F_ACAT1_ACAT2" /><text
6212 style="font-size:10px;font-family:Calibri"
6213 id="text1671"
6214 class="st17 st18"
6215 x="710.4895"
6216 y="542.85089">AcCoA</text>
6217 <path
6218 style="fill:none;stroke:#000000;stroke-width:2.22309995"
6219 d="m 716.3,520.51855 c -6.4,-2.1 -6.4,-2.1 -6.4,-2.1 l 6.5,-1.8 -1.7,1.9 1.6,2 z m 5.8,7.9 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
6220 class="st157"
6221 inkscape:label="ACAT1_ACAT2 B"
6222 inkscape:connector-curvature="0"
6223 id="B_ACAT1_ACAT2" /><text
6224 style="font-size:16px;font-family:Calibri-Bold"
6225 id="text1674"
6226 class="st15 st16"
6227 x="749.35974"
6228 y="522.77277">AcAcCoA</text>
6229 <path
6230 style="fill:none;stroke:#000000;stroke-width:1.83369994"
6231 d="m 841.4,518.71855 c -5.9,1 -4.4,9.5 -4.4,9.5 m -18.1,-9.5 c -5.9,1 -4.4,9.5 -4.4,9.5 m 7.6,-9.6 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 21.3,11.7 -37.5,-0.4"
6232 class="st158"
6233 inkscape:label="HMGCS1_HMGCS2 "
6234 inkscape:connector-curvature="0"
6235 id="R_HMGCS1_HMGCS2" /><text
6236 style="font-size:10px;font-family:Calibri"
6237 id="text1677"
6238 class="st17 st18"
6239 x="828.9563"
6240 y="536.06281">H</text>
6241 <text
6242 style="font-size:6.09369993px;font-family:Calibri"
6243 id="text1679"
6244 class="st17 st26"
6245 x="835.18683"
6246 y="538.06281">2</text>
6247 <text
6248 style="font-size:10px;font-family:Calibri"
6249 id="text1681"
6250 class="st17 st18"
6251 x="838.2757"
6252 y="536.06281">O</text>
6253 <text
6254 style="font-size:10px;font-family:Calibri"
6255 id="text1683"
6256 class="st17 st18"
6257 x="798.9895"
6258 y="535.35089">AcCoA</text>
6259 <text
6260 style="font-size:10px;font-family:Calibri"
6261 id="text1685"
6262 class="st17 st18"
6263 x="818.22681"
6264 y="501.87915">CoA</text>
6265 <path
6266 style="fill:none;stroke:#000000;stroke-width:2.22309995"
6267 d="m 846,521.01855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -21,-11.6 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6268 class="st157"
6269 inkscape:label="HMGCS1_HMGCS2 f"
6270 inkscape:connector-curvature="0"
6271 id="F_HMGCS1_HMGCS2" /><text
6272 style="font-size:16px;font-family:Calibri-Bold"
6273 id="text1688"
6274 class="st15 st16"
6275 x="855.85974"
6276 y="522.77277">HMGCoA</text>
6277 <path
6278 style="fill:none;stroke:#000000;stroke-width:2.22309995"
6279 d="m 1035.4,520.81855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -102.4,-11.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 25.9,0.4 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 33,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 18,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 16.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6280 class="st157"
6281 inkscape:label="MVD f"
6282 inkscape:connector-curvature="0"
6283 id="F_MVD" /><path
6284 style="fill:none;stroke:#000000;stroke-width:1.85309994"
6285 d="m 1269.2,518.61855 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m -24.9,10.1 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m -27.9,10.1 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m -51.9,10.1 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m 57.3,10.3 c -5.9,1 -4.4,9.6 -4.4,9.6 m -15.8,-9.6 c -5.9,1 -4.4,9.6 -4.4,9.6 m -36.9,-10.1 c -5.9,1 -4.4,9.6 -4.4,9.6 m 105.2,-9.1 -133.5,-0.2 m 9.1,-0.1 c -5.9,1 -4.4,9.6 -4.4,9.6 m 4.3,-9.5 c 5.9,-1.2 5.4,-10.1 5.4,-10.1"
6286 class="st159"
6287 inkscape:label="DHCR24_LEFTY1"
6288 inkscape:connector-curvature="0"
6289 id="R_DHCR24_LEFTY1" /><path
6290 style="fill:none;stroke:#000000;stroke-width:2.22309995"
6291 d="m 1113.4,520.51855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -11.1,-10.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6292 class="st157"
6293 inkscape:label="ARID4B_GGPS1_FDPS_FDPSP7_2 f"
6294 inkscape:connector-curvature="0"
6295 id="F_ARID4B_GGPS1_FDPS_FDPSP7_2" /><path
6296 style="fill:none;stroke:#000000;stroke-width:2.22309995"
6297 d="m 1281,520.71855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -7.8,-11.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -19.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -22.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -46.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -22.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6298 class="st157"
6299 inkscape:label="DHCR24_LEFTY1 f"
6300 inkscape:connector-curvature="0"
6301 id="F_DHCR24_LEFTY1" /><path
6302 style="fill:none;stroke:#000000;stroke-width:2.22309995"
6303 d="m 768.2,457.11855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -35,0.2 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 45.6,8.8 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
6304 class="st157"
6305 inkscape:label="ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2 f"
6306 inkscape:connector-curvature="0"
6307 id="F_ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2" /><path
6308 style="fill:none;stroke:#000000;stroke-width:2.22309995"
6309 d="m 779,432.11855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -16,-11.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6310 class="st157"
6311 inkscape:label="FASN_1 f"
6312 inkscape:connector-curvature="0"
6313 id="F_FASN_1" /><path
6314 style="fill:none;stroke:#000000;stroke-width:2.5"
6315 d="m 864.2,457.11855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 11.6,9.6 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
6316 class="st22"
6317 inkscape:connector-curvature="0"
6318 id="F_MCAT_FASN" /><path
6319 style="fill:none;stroke:#000000;stroke-width:2.5"
6320 d="m 1093.3,432.21855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -11.1,-11.5 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -51.2,-1.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 25,0.2 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -63.6,1.2 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6321 class="st22"
6322 inkscape:label="OLAH_FASN f"
6323 inkscape:connector-curvature="0"
6324 id="F_OLAH_FASN" /><path
6325 style="fill:none;stroke:#000000;stroke-width:2.2256"
6326 d="m 975.2,225.31855 c -6,1.1 -5.5,9 -5.5,9 m -30.5,-9 c -6,1.1 -5.5,9 -5.5,9 m -50,-9 c -6,1.1 -5.5,9 -5.5,9 m -39.5,-9 c -6,1.1 -5.5,9 -5.5,9 m 98.6,-9.1 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -71.9,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m 16.6,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -67.6,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m 85.1,10.6 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -73.5,9.4 c 6,-1 4.5,-9.4 4.5,-9.4 m 15.7,9.9 c -6,1.1 -5.5,9 -5.5,9 m -37,-9.1 c -6,1.1 -5.5,9 -5.5,9 m 99.1,-8.8 c -6,1.1 -5.5,9 -5.5,9 m 73.4,-9.2 -174.7,-0.1"
6327 class="st160"
6328 inkscape:label="ATIC_2"
6329 inkscape:connector-curvature="0"
6330 id="R_ATIC_2" /><path
6331 style="fill:none;stroke:#000000;stroke-width:2.5"
6332 d="m 981.4,227.31855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -46.6,-11.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -26.4,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -21,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -21.8,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6333 class="st22"
6334 inkscape:label="ATIC_2 f"
6335 inkscape:connector-curvature="0"
6336 id="F_ATIC_2" /><path
6337 style="fill:none;stroke:#000000;stroke-width:2.06660008"
6338 d="m 926.5,278.81855 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -22.6,8.2 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -25.6,8.2 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -28.6,8.5 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -27.1,8.5 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m 56.9,8.8 c -6,1.1 -5.5,9.2 -5.5,9.2 m -12.5,-9.2 c -6,1.1 -5.5,9.2 -5.5,9.2 m -14,-9.7 c -6,1.1 -5.5,9.2 -5.5,9.2 m -15.5,-9.2 c -6,1.1 -5.5,9.2 -5.5,9.2 m -11,-9.5 c -6,1.1 -5.5,9.2 -5.5,9.2 m -31.5,-9.3 148.9,1.2 m -134.4,-1.1 c -6,1.1 -5.5,9.2 -5.5,9.2 m 2.5,-8.7 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -16.1,-40.9 c 0,49.6 0,49.6 0,49.6"
6339 class="st161"
6340 inkscape:label="UMPS_2"
6341 inkscape:connector-curvature="0"
6342 id="R_UMPS_2" /><path
6343 style="fill:none;stroke:#000000;stroke-width:1.7335"
6344 d="m 1087.7,225.31855 -51.1,-0.3 m 13,0 c -6,0.8 -5.5,6.9 -5.5,6.9 m 12.9,-7.1 c 6,-1 4.5,-9.4 4.5,-9.4 m -18.9,9.8 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m 27.3,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -10.4,10 c -6,0.8 -5.5,6.9 -5.5,6.9"
6345 class="st162"
6346 inkscape:connector-curvature="0"
6347 id="R_TNRC6B_ADSL_1" /><path
6348 style="fill:none;stroke:#000000;stroke-width:2.5"
6349 d="m 1086.5,227.21855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -9.3,-11 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -17.3,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -14.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6350 class="st22"
6351 inkscape:connector-curvature="0"
6352 id="F_TNRC6B_ADSL_1" /><text
6353 style="font-size:10px;font-family:Calibri"
6354 id="text1703"
6355 class="st17 st18"
6356 x="1059.1674"
6357 y="207.14964">Pi</text>
6358 <path
6359 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6360 d="m 1256.9,272.21855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -8.6,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
6361 class="st32"
6362 inkscape:label="GUK1_1 f"
6363 inkscape:connector-curvature="0"
6364 id="F_GUK1_1" /><path
6365 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6366 d="m 1234.2,272.11855 c -6.9,-2 -6.9,-2 -6.9,-2 l 6.8,-2.4 -1.7,2.2 1.8,2.2 z m 3.6,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
6367 class="st32"
6368 inkscape:label="GUK1_1 b"
6369 inkscape:connector-curvature="0"
6370 id="B_GUK1_1" /><path
6371 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6372 d="m 1321.7,270.71855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -7.7,8.8 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
6373 class="st32"
6374 inkscape:label="RRM2B_TXN_RRM1_RRM2B_1 f"
6375 inkscape:connector-curvature="0"
6376 id="F_RRM2B_TXN_RRM1_RRM2B_1" /><text
6377 style="font-size:10px;font-family:Calibri"
6378 id="text1708"
6379 class="st17 st18"
6380 x="1379.2269"
6381 y="295.87714">ADP</text>
6382 <text
6383 style="font-size:10px;font-family:Calibri"
6384 id="text1710"
6385 class="st17 st18"
6386 x="1397.4281"
6387 y="296.41336">ATP</text>
6388 <path
6389 style="fill:none;stroke:#000000;stroke-width:1.92519999"
6390 d="m 1410.2,269.91855 c -24.9,0 -24.9,0 -24.9,0 m 16.5,9.5 c 2.4,-5.9 -3.6,-9.5 -3.6,-9.5 m -2.6,0.1 c -5,0.9 -4.4,9.3 -4.4,9.3"
6391 class="st148"
6392 inkscape:label="GUK1_2"
6393 inkscape:connector-curvature="0"
6394 id="R_GUK1_2" /><path
6395 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6396 d="m 1409.9,272.31855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -8.5,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
6397 class="st32"
6398 inkscape:label="GUK1_2 f"
6399 inkscape:connector-curvature="0"
6400 id="F_GUK1_2" /><path
6401 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6402 d="m 1386,271.61855 c -6.9,-2 -6.9,-2 -6.9,-2 l 6.8,-2.4 -1.7,2.2 1.8,2.2 z m 3.5,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
6403 class="st32"
6404 inkscape:label="GUK1_2 b"
6405 inkscape:connector-curvature="0"
6406 id="B_GUK1_2" /><text
6407 style="font-size:16px;font-family:Calibri-Bold"
6408 id="text1715"
6409 class="st15 st16"
6410 x="1420.6156"
6411 y="273.48557">dGMP</text>
6412 <path
6413 style="fill:none;stroke:#000000;stroke-width:1.68470001"
6414 d="m 1156.6,213.31855 c -2.4,6.7 3.6,10.9 3.6,10.9 m 15.7,0.2 c -26.9,0 -26.9,0 -26.9,0 m 19.4,-11.1 c 2.4,6.7 -3.6,10.9 -3.6,10.9"
6415 class="st163"
6416 inkscape:label="AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1"
6417 inkscape:connector-curvature="0"
6418 id="R_AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1" /><path
6419 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6420 d="m 1152.2,221.91855 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z m 1.9,-8.8 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6421 class="st32"
6422 inkscape:label="AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1 f"
6423 inkscape:connector-curvature="0"
6424 id="F_AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1" /><path
6425 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6426 d="m 1175.9,222.21855 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z m -8.6,-9.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6427 class="st32"
6428 inkscape:label="AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1 b"
6429 inkscape:connector-curvature="0"
6430 id="B_AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1" /><path
6431 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6432 d="m 1238.3,226.01855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -8.5,8.6 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
6433 class="st32"
6434 inkscape:label="RRM2B_TXN_RRM1_RRM2B_2 f"
6435 inkscape:connector-curvature="0"
6436 id="F_RRM2B_TXN_RRM1_RRM2B_2" /><path
6437 style="fill:none;stroke:#000000;stroke-width:2.5"
6438 d="m 937.8,280.91855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -8.4,-10.3 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -18,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -21,-0.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -24,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -22.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -39,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
6439 class="st22"
6440 inkscape:label="UMPS_2 F"
6441 inkscape:connector-curvature="0"
6442 id="F_UMPS_2" /><path
6443 style="fill:none;stroke:#000000;stroke-width:2.48839998"
6444 d="m 965.8,316.01855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2,-7.4 -2.1,1.9 -2.1,-1.8 z m 12.7,-5.1 c 4.3,-1.4 4.3,-1.4 4.3,-1.4 l -4.4,-1 1.1,1.1 -1,1.3 z"
6445 class="st164"
6446 inkscape:label="CMPK2_CMPK1_1 f"
6447 inkscape:connector-curvature="0"
6448 id="F_CMPK2_CMPK1_1" /><path
6449 style="fill:none;stroke:#000000;stroke-width:2.48839998"
6450 d="m 970,295.11855 c -2.2,-7.3 -2.2,-7.3 -2.2,-7.3 l -2,7.4 2.1,-1.9 2.1,1.8 z m 8.5,4.8 c 4.3,-1.4 4.3,-1.4 4.3,-1.4 l -4.4,-1 1.1,1.1 -1,1.3 z"
6451 class="st164"
6452 inkscape:label="CMPK2_CMPK1_1 b"
6453 inkscape:connector-curvature="0"
6454 id="B_CMPK2_CMPK1_1" /><path
6455 style="fill:none;stroke:#000000;stroke-width:2.31130004"
6456 d="m 933.3,323.31855 c -1.9,-4.3 -1.9,-4.3 -1.9,-4.3 l -1.4,4.4 1.6,-1.2 1.7,1.1 z m -11,11.6 c -7.2,-2.4 -7.2,-2.4 -7.2,-2.4 l 7.4,-1.9 -1.9,2.1 1.7,2.2 z"
6457 class="st165"
6458 inkscape:label="RRM2B_TXN_RRM1_RRM2_1 f"
6459 inkscape:connector-curvature="0"
6460 id="F_RRM2B_TXN_RRM1_RRM2_1" /><path
6461 style="fill:none;stroke:#000000;stroke-width:2.31130004"
6462 d="m 836,334.81855 c -7.2,-2.4 -7.2,-2.4 -7.2,-2.4 l 7.4,-1.9 -1.9,2.1 1.7,2.2 z m 8.7,-11.2 c -1.9,-4.3 -1.9,-4.3 -1.9,-4.3 l -1.4,4.4 1.6,-1.2 1.7,1.1 z"
6463 class="st165"
6464 inkscape:label="CMPK1_DTYMK f"
6465 inkscape:connector-curvature="0"
6466 id="F_CMPK1_DTYMK" /><path
6467 style="fill:none;stroke:#000000;stroke-width:2.31130004"
6468 d="m 859.9,334.81855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -6.8,-10.8 c 1.9,-4.3 1.9,-4.3 1.9,-4.3 l 1.4,4.4 -1.6,-1.2 -1.7,1.1 z"
6469 class="st165"
6470 inkscape:label="CMPK1_DTYMK b"
6471 inkscape:connector-curvature="0"
6472 id="B_CMPK1_DTYMK" /><path
6473 style="fill:none;stroke:#000000;stroke-width:2.31130004"
6474 d="m 731.1,335.41855 c -7.2,-2.4 -7.2,-2.4 -7.2,-2.4 l 7.4,-1.9 -1.9,2.1 1.7,2.2 z m 9.1,-12.4 c -1.7,-4.7 -1.7,-4.7 -1.7,-4.7 l -1.1,4.8 1.3,-1.3 1.5,1.2 z"
6475 class="st165"
6476 inkscape:label="TYMS "
6477 inkscape:connector-curvature="0"
6478 id="F_TYMS" /><path
6479 style="fill:none;stroke:#000000;stroke-width:2.31130004"
6480 d="m 770.6,330.81855 c 7.2,2.4 7.2,2.4 7.2,2.4 l -7.4,1.9 1.9,-2.1 -1.7,-2.2 z m -4.7,-8.4 c -1.9,-5.3 -1.9,-5.3 -1.9,-5.3 l -1.8,5.3 1.8,-1.3 1.9,1.3 z"
6481 class="st165"
6482 inkscape:label="TYMS b"
6483 inkscape:connector-curvature="0"
6484 id="B_TYMS" /><path
6485 style="fill:none;stroke:#000000;stroke-width:1.82930005"
6486 d="m 995.7,334.41855 c -7.4,-1.9 -7.4,-1.9 -7.4,-1.9 l 7.2,-2.4 -1.8,2.2 2,2.1 z m 3.8,6 c 1.6,4.7 1.6,4.7 1.6,4.7 l 2.4,-4.6 -2.1,1.1 -1.9,-1.2 z"
6487 class="st109"
6488 inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3 f"
6489 inkscape:connector-curvature="0"
6490 id="F_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3" /><path
6491 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6492 d="m 1093.9,325.01855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m 9.7,9.9 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
6493 class="st73"
6494 inkscape:label="CTPS2_GATM_CTPS1 f"
6495 inkscape:connector-curvature="0"
6496 id="F_CTPS2_GATM_CTPS1" /><text
6497 style="font-size:10px;font-family:Calibri"
6498 id="text1731"
6499 class="st17 st18"
6500 x="1236.1302"
6501 y="316.99045">ATP</text>
6502 <text
6503 style="font-size:10px;font-family:Calibri"
6504 id="text1733"
6505 class="st17 st18"
6506 x="1216.7562"
6507 y="317.36545">ADP</text>
6508 <path
6509 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6510 d="m 1229.5,324.71855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m -7,5.6 c -7.4,1.9 -7.4,1.9 -7.4,1.9 l 7.2,2.4 -1.8,-2.2 2,-2.1 z"
6511 class="st73"
6512 inkscape:label="CMPK2_CMPK1_2 b"
6513 inkscape:connector-curvature="0"
6514 id="B_CMPK2_CMPK1_2" /><path
6515 style="fill:none;stroke:#000000;stroke-width:2.5"
6516 d="m 1246.1,335.71855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -3.6,-10.9 c -1.1,-5.1 -1.1,-5.1 -1.1,-5.1 l -1.7,5 1.5,-1.2 1.3,1.3 z"
6517 class="st22"
6518 inkscape:label="CMPK2_CMPK1_2 f"
6519 inkscape:connector-curvature="0"
6520 id="F_CMPK2_CMPK1_2" /><path
6521 style="fill:none;stroke:#000000;stroke-width:1.82930005"
6522 d="m 1218.5,332.61855 28.3,0.4 m -18.4,-9.2 c -2.2,5.6 3.9,8.9 3.9,8.9 m 4.8,0 c 5,-0.9 4,-8.9 4,-8.9"
6523 class="st109"
6524 inkscape:label="CMPK2_CMPK1_2"
6525 inkscape:connector-curvature="0"
6526 id="R_CMPK2_CMPK1_2" /><path
6527 style="fill:none;stroke:#000000;stroke-width:2.31130004"
6528 d="m 1196.6,360.01855 c 2.4,7.2 2.4,7.2 2.4,7.2 l 1.9,-7.4 -2.1,1.9 -2.2,-1.7 z m -6.1,-7.6 c -4.6,1 -4.6,1 -4.6,1 l 2.7,-3.7 0,1.9 1.9,0.8 z"
6529 class="st165"
6530 inkscape:connector-curvature="0"
6531 id="F_RRM2B_TXN_RRM1_RRM2_2" /><text
6532 style="font-size:16px;font-family:Calibri-Bold"
6533 id="text1739"
6534 class="st15 st16"
6535 x="1258.7123"
6536 y="382.35764">dCMP</text>
6537 <text
6538 style="font-size:10px;font-family:Calibri"
6539 id="text1741"
6540 class="st17 st18"
6541 x="1236.1302"
6542 y="361.80984">ATP</text>
6543 <text
6544 style="font-size:10px;font-family:Calibri"
6545 id="text1743"
6546 class="st17 st18"
6547 x="1216.7562"
6548 y="362.36545">ADP</text>
6549 <path
6550 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6551 d="m 1229.5,369.71855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m -7,5.6 c -7.4,1.9 -7.4,1.9 -7.4,1.9 l 7.2,2.4 -1.8,-2.2 2,-2.1 z"
6552 class="st73"
6553 inkscape:label="CMPK2_CMPK1_3 b"
6554 inkscape:connector-curvature="0"
6555 id="B_CMPK2_CMPK1_3" /><path
6556 style="fill:none;stroke:#000000;stroke-width:2.5"
6557 d="m 1246.1,380.71855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -3.6,-10.9 c -1.1,-5.1 -1.1,-5.1 -1.1,-5.1 l -1.7,5 1.5,-1.2 1.3,1.3 z"
6558 class="st22"
6559 inkscape:label="CMPK2_CMPK1_3 f"
6560 inkscape:connector-curvature="0"
6561 id="F_CMPK2_CMPK1_3" /><path
6562 style="fill:none;stroke:#000000;stroke-width:1.82930005"
6563 d="m 1218.5,377.61855 28.3,0.4 m -18.4,-9.2 c -2.2,5.6 3.9,8.9 3.9,8.9 m 4.8,0 c 5,-0.9 4,-8.9 4,-8.9"
6564 class="st109"
6565 inkscape:label="CMPK2_CMPK1_3"
6566 inkscape:connector-curvature="0"
6567 id="R_CMPK2_CMPK1_3" /><path
6568 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6569 d="m 236.8,382.21855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z m -52.2,-23.9 c -6.2,2.5 -6.2,2.5 -6.2,2.5 l 6.5,1.5 -1.7,-1.8 1.4,-2.2 z"
6570 class="st73"
6571 inkscape:label="MTHFD1_3 f"
6572 inkscape:connector-curvature="0"
6573 id="F_MTHFD1_3" /><path
6574 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6575 d="m 206.6,426.41855 c -6.2,2.5 -6.2,2.5 -6.2,2.5 l 6.5,1.5 -1.7,-1.8 1.4,-2.2 z m 31.7,-24 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
6576 class="st73"
6577 inkscape:label="MTHFD1_3 b"
6578 inkscape:connector-curvature="0"
6579 id="B_MTHFD1_3" /><text
6580 style="font-size:9.99962234px;font-family:Calibri"
6581 id="text1750"
6582 class="st17 st18"
6583 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6584 x="301.1604"
6585 y="383.42343">H</text>
6586 <text
6587 style="font-size:6.09346962px;font-family:Calibri"
6588 id="text1752"
6589 class="st17 st26"
6590 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6591 x="307.39139"
6592 y="385.42346">2</text>
6593 <text
6594 style="font-size:9.99962234px;font-family:Calibri"
6595 id="text1754"
6596 class="st17 st18"
6597 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6598 x="310.4798"
6599 y="383.42337">O</text>
6600 <path
6601 style="fill:none;stroke:#000000;stroke-width:2.29760003"
6602 d="m 290,301.91855 c 1.6,-5.3 17.5,-4.5 17.5,-4.5 m -2.3,19.7 c -9.8,2.5 -15.9,-3.8 -15.9,-3.8 m -0.3,11.1 0.2,-34.2"
6603 class="st79"
6604 inkscape:label="MTHFD2_2"
6605 inkscape:connector-curvature="0"
6606 id="R_MTHFD2_2" /><path
6607 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6608 d="m 287,292.01855 c 2.3,-6.3 2.3,-6.3 2.3,-6.3 l 1.6,6.5 -1.9,-1.7 -2,1.5 z m 15.6,3.3 c 7,1.6 7,1.6 7,1.6 l -6.9,1.6 1.7,-1.6 -1.8,-1.6 z"
6609 class="st73"
6610 inkscape:label="MTHFD2_2 f"
6611 inkscape:connector-curvature="0"
6612 id="F_MTHFD2_2" /><path
6613 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6614 d="m 301.3,316.11855 c 7,1.6 7,1.6 7,1.6 l -6.9,1.6 1.7,-1.6 -1.8,-1.6 z m -10.5,6.6 c -2,7.3 -2,7.3 -2,7.3 l -2.3,-7.3 2.2,1.8 2.1,-1.8 z"
6615 class="st73"
6616 inkscape:label="MTHFD2_2 b"
6617 inkscape:connector-curvature="0"
6618 id="B_MTHFD2_2" /><text
6619 style="font-size:10px;font-family:Calibri"
6620 id="text1759"
6621 class="st17 st18"
6622 transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
6623 x="311.63144"
6624 y="319.94809">NADH</text>
6625 <text
6626 style="font-size:9.99962234px;font-family:Calibri"
6627 id="text1761"
6628 class="st17 st18"
6629 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6630 x="307.66241"
6631 y="303.30228">NAD</text>
6632 <path
6633 style="fill:none;stroke:#000000;stroke-width:1.87170005"
6634 d="m 402.2,547.01855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 34,12.7 c 6.3,-2.3 6.3,-2.3 6.3,-2.3 l -6.5,-1.6 1.7,1.9 -1.5,2 z"
6635 class="st30"
6636 inkscape:label="PEPCK f"
6637 inkscape:connector-curvature="0"
6638 id="F_PEPCK" /><path
6639 style="fill:none;stroke:#000000;stroke-width:2.82299995"
6640 d="m 268.8,649.41855 c 2.3,7.2 2.3,7.2 2.3,7.2 l 2,-7.3 -2.1,1.9 -2.2,-1.8 z m -11.1,-9.3 c -5.1,1.5 -5.1,1.5 -5.1,1.5 l 5.5,1.8 -1.5,-1.7 1.1,-1.6 z"
6641 class="st45"
6642 inkscape:label="FH_3 f"
6643 inkscape:connector-curvature="0"
6644 id="F_FH_3" /><path
6645 style="fill:none;stroke:#000000;stroke-width:2.23090005"
6646 d="m 1444.3,1060.1186 c 2.4,-5.7 2.4,-5.7 2.4,-5.7 l 2,5.8 -2.1,-1.5 -2.3,1.4 z m 57.4,10.4 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
6647 class="st37"
6648 inkscape:connector-curvature="0"
6649 id="B_SLC25A5_SLC25A4_SLC25A6" /><path
6650 style="fill:none;stroke:#000000;stroke-width:2.18210006"
6651 d="m 1050.3,691.11855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z m 11.6,-3.8 c 4.7,1.4 4.7,1.4 4.7,1.4 l -5.1,1.5 1.4,-1.4 -1,-1.5 z"
6652 class="st14"
6653 inkscape:label="TransportGlu f"
6654 inkscape:connector-curvature="0"
6655 id="F_TransportGlu" /><path
6656 style="fill:none;stroke:#000000;stroke-width:2.15549994"
6657 d="m 954.1,690.71855 c 2.2,7.1 2.2,7.1 2.2,7.1 l 2.2,-7.1 -2.2,1.8 -2.2,-1.8 z m 12.5,-2.2 c 4.7,1.3 4.7,1.3 4.7,1.3 l -5.1,1.4 1.4,-1.4 -1,-1.3 z"
6658 class="st166"
6659 inkscape:label="TransportGln f"
6660 inkscape:connector-curvature="0"
6661 id="F_TransportGln" /><path
6662 style="fill:none;stroke:#000000;stroke-width:2.18210006"
6663 d="m 956,636.91855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z m 77.1,-13.1 c -1.4,4.7 -1.4,4.7 -1.4,4.7 l -1.5,-5.1 1.4,1.4 1.5,-1 z m -48,0.4 c -1.4,4.7 -1.4,4.7 -1.4,4.7 l -1.5,-5.1 1.4,1.4 1.5,-1 z"
6664 class="st14"
6665 inkscape:label="GS f"
6666 inkscape:connector-curvature="0"
6667 id="F_GS" /><path
6668 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6669 d="m 1022.5,652.11855 c 6.9,2.1 6.9,2.1 6.9,2.1 l -6.9,2.3 1.7,-2.2 -1.7,-2.2 z m -14.8,-6.7 c 1.4,-4.7 1.4,-4.7 1.4,-4.7 l 1.5,5.1 -1.4,-1.4 -1.5,1 z"
6670 class="st32"
6671 inkscape:label="GLS2 f"
6672 inkscape:connector-curvature="0"
6673 id="F_GLS2" /><path
6674 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6675 d="m 1029.4,709.51855 c 6.9,-2.1 6.9,-2.1 6.9,-2.1 l -6.9,-2.3 1.7,2.2 -1.7,2.2 z m -17.8,-8.9 c 0.9,-4.9 0.9,-4.9 0.9,-4.9 l -3.6,3.9 1.9,-0.6 0.8,1.6 z"
6676 class="st32"
6677 inkscape:label="GLS f"
6678 inkscape:connector-curvature="0"
6679 id="F_GLS" /><path
6680 style="fill:none;stroke:#000000;stroke-width:1.99090004"
6681 d="m 1270.4,787.81855 c 2.8,-7.3 -3.1,-12.1 -3.1,-12.1 m 49.7,12.1 c 2.8,-7.3 -3.1,-12.1 -3.1,-12.1 m -17.1,12.1 c 2.8,-7.3 -3.1,-12.1 -3.1,-12.1 m -53.7,0.4 c -5.3,0.6 -5,7.6 -5,7.6 m 89.5,-8 c -99.3,0 -99.3,0 -99.3,0 m 29.8,0.4 c -5.3,0.6 -5,7.6 -5,7.6"
6682 class="st167"
6683 inkscape:label="CPS1"
6684 inkscape:connector-curvature="0"
6685 id="R_CPS1" /><text
6686 style="font-size:16.00031662px;font-family:Calibri-Bold"
6687 id="text1772"
6688 class="st15 st16"
6689 transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
6690 x="1205.1744"
6691 y="771.00928">CP</text>
6692 <path
6693 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6694 d="m 1351.5,622.81855 c -6.9,-1.7 -6.9,-1.7 -6.9,-1.7 l 5.5,4.6 -0.8,-2.2 2.2,-0.7 z m 11,-3.3 c -1.8,-7.4 -1.8,-7.4 -1.8,-7.4 l -2.5,7.2 2.2,-1.7 2.1,1.9 z"
6695 class="st73"
6696 inkscape:label="ALDH4A1_2 f"
6697 inkscape:connector-curvature="0"
6698 id="F_ALDH4A1_2" /><text
6699 style="font-size:9.99962234px;font-family:Calibri"
6700 id="text1775"
6701 class="st17 st18"
6702 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6703 x="1386.1115"
6704 y="542.35461">Gly</text>
6705 <text
6706 style="font-size:9.99962234px;font-family:Calibri"
6707 id="text1777"
6708 class="st17 st18"
6709 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6710 x="1404.1106"
6711 y="542.55579">GA</text>
6712 <path
6713 style="fill:none;stroke:#000000;stroke-width:2.5"
6714 d="m 952,862.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -12.1,9.3 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z"
6715 class="st22"
6716 inkscape:label="CA5B_CA5A f"
6717 inkscape:connector-curvature="0"
6718 id="F_CA5B_CA5A" /><text
6719 style="font-size:9.99962234px;font-family:Calibri"
6720 id="text1780"
6721 class="st17 st18"
6722 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6723 x="665.34772"
6724 y="1031.6384">H</text>
6725 <text
6726 style="font-size:6.09346962px;font-family:Calibri"
6727 id="text1782"
6728 class="st17 st26"
6729 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6730 x="671.57819"
6731 y="1033.6384">2</text>
6732 <text
6733 style="font-size:9.99962234px;font-family:Calibri"
6734 id="text1784"
6735 class="st17 st18"
6736 transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
6737 x="674.66699"
6738 y="1031.6384">O</text>
6739 <path
6740 style="fill:none;stroke:#000000;stroke-width:2.29760003"
6741 d="m 707.7,1012.8186 c 2.9,-9.7 -3.2,-16.00005 -3.2,-16.00005 m -47.9,0.2 61.6,-0.1 m -33,15.90005 c 2.9,-9.7 -3.2,-16.00005 -3.2,-16.00005 m -14.3,0.3 c -5.3,1.4 -5.1,17.30005 -5.1,17.30005"
6742 class="st79"
6743 inkscape:label="SHMT1_2 "
6744 inkscape:connector-curvature="0"
6745 id="R_SHMT1_2" /><path
6746 style="fill:none;stroke:#000000;stroke-width:2.09949994"
6747 d="m 707,1008.9186 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z m 10.5,-9.70005 c 6.3,-2.3 6.3,-2.3 6.3,-2.3 l -6.5,-1.7 1.7,1.9 -1.5,2.1 z m -33,9.70005 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z"
6748 class="st73"
6749 inkscape:label="SHMT1_2 f"
6750 inkscape:connector-curvature="0"
6751 id="F_SHMT1_2" /><path
6752 style="fill:none;stroke:#000000;stroke-width:2.5"
6753 d="m 1442.5,809.71855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
6754 class="st22"
6755 inkscape:label="TransportFolate f"
6756 inkscape:connector-curvature="0"
6757 id="path1985" /><path
6758 style="fill:none;stroke:#000000;stroke-width:2.5"
6759 d="m 1489.5,814.81855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
6760 class="st22"
6761 inkscape:label="SLC16A3_SLC16A1_SLC16A5_2 f"
6762 inkscape:connector-curvature="0"
6763 id="F_SLC16A3_SLC16A1_SLC16A5_2" /><path
6764 style="fill:none;stroke:#000000;stroke-width:2.5"
6765 d="m 1490.3,756.31855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
6766 class="st22"
6767 inkscape:transform-center-y="-3.0492074"
6768 inkscape:transform-center-x="0.87100132"
6769 inkscape:label="Transport_serine b"
6770 inkscape:connector-curvature="0"
6771 id="B_Transport_serine" /><text
6772 style="font-size:10.00011921px;font-family:Calibri"
6773 id="text1791"
6774 class="st17 st18"
6775 transform="matrix(0.99998813,0.00487302,-0.00487302,0.99998813,0,0)"
6776 x="835.31476"
6777 y="1042.428">formate+ATP</text>
6778 <text
6779 style="font-size:10.00011921px;font-family:Calibri"
6780 id="text1793"
6781 class="st17 st18"
6782 transform="matrix(0.99998813,0.00487302,-0.00487302,0.99998813,0,0)"
6783 x="891.94086"
6784 y="1042.8938">ADP+Pi</text>
6785 <path
6786 style="fill:none;stroke:#000000;stroke-width:1.80649996"
6787 d="m 1525.5,392.51855 c -5.4,-1.7 -4.9,-14 -4.9,-14 m 10.8,14.3 c 5.5,-1.1 4.1,-10.6 4.1,-10.6 m 9,10.6 -33.9,-0.3"
6788 class="st116"
6789 inkscape:label="LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1"
6790 inkscape:connector-curvature="0"
6791 id="R_LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1" /><path
6792 style="fill:none;stroke:#000000;stroke-width:2.5"
6793 d="m 1543.5,394.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -6.5,-11.3 c -1.7,-5.2 -1.7,-5.2 -1.7,-5.2 l -1.4,5.3 1.5,-1.4 1.6,1.3 z"
6794 class="st22"
6795 inkscape:label="LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1 f"
6796 inkscape:connector-curvature="0"
6797 id="F_LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1" /><path
6798 style="fill:none;stroke:#000000;stroke-width:2.5"
6799 d="m 1543.5,348.31855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -6.5,-11.3 c -1.7,-5.2 -1.7,-5.2 -1.7,-5.2 l -1.4,5.3 1.5,-1.4 1.6,1.3 z"
6800 class="st22"
6801 inkscape:label="CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13 f"
6802 inkscape:connector-curvature="0"
6803 id="F_CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13" /><path
6804 style="fill:none;stroke:#000000;stroke-width:9.22049999;stroke-linecap:round;stroke-linejoin:round;stroke-miterlimit:2"
6805 inkscape:connector-curvature="0"
6806 d="m 290.9,65.418554 1141.8,0 c 111.4,0 201.6,90.299996 201.6,201.599996 l 0,777.20005 c 0,111.4 -90.3,201.6 -201.6,201.6 l -1141.8,0 c -111.4,0 -201.6,-90.3 -201.6,-201.6 l 0,-777.10005 c 0,-111.4 90.3,-201.699996 201.6,-201.699996 z"
6807 class="st168"
6808 id="rect3173" /><text
6809 style="font-size:10px;font-family:Calibri"
6810 id="text1799"
6811 class="st17 st18"
6812 x="1582.0922"
6813 y="894.75116">AMP+PPi</text>
6814 <text
6815 style="font-size:10px;font-family:Calibri"
6816 id="text1801"
6817 class="st17 st18"
6818 x="1583.309"
6819 y="884.0647">ATP+CoA</text>
6820 <path
6821 style="fill:none;stroke:#000000;stroke-width:1.92519999"
6822 d="m 1565.4,888.01855 c 0.9,5 9.3,4.4 9.3,4.4 m 4.5,-10.4 c -8.6,-2.3 -13.9,3.4 -13.9,3.4 m -0.1,-11.9 c 0,24.9 0,24.9 0,24.9"
6823 class="st148"
6824 inkscape:label="palmitateActivation"
6825 inkscape:connector-curvature="0"
6826 id="R_palmitateActivation" /><path
6827 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6828 d="m 1567.3,897.51855 c -2,6.9 -2,6.9 -2,6.9 l -2.4,-6.8 2.2,1.7 2.2,-1.8 z m 7.4,-3.5 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
6829 class="st32"
6830 inkscape:label="palmitateActivation f"
6831 inkscape:connector-curvature="0"
6832 id="F_palmitateActivation" /><text
6833 style="font-size:16px;font-family:Calibri-Bold"
6834 id="text1805"
6835 class="st15 st16"
6836 x="1547.4984"
6837 y="863.4964">Palm</text>
6838 <text
6839 style="font-size:16px;font-family:Calibri-Bold"
6840 id="text1807"
6841 class="st15 st16"
6842 x="1537.4193"
6843 y="918.66138">PalmCoA</text>
6844 <text
6845 style="font-size:10px;font-family:Calibri"
6846 id="text1809"
6847 class="st17 st18"
6848 x="1582.8129"
6849 y="953.61157">CoA</text>
6850 <text
6851 style="font-size:10px;font-family:Calibri"
6852 id="text1811"
6853 class="st17 st18"
6854 x="1582.9476"
6855 y="942.5647">carnitine</text>
6856 <path
6857 style="fill:none;stroke:#000000;stroke-width:1.92519999"
6858 d="m 1565.2,932.01855 c 0,24.9 0,24.9 0,24.9 m 9.6,-16.5 c -5.9,-2.4 -9.5,3.6 -9.5,3.6 m 0.1,2.5 c 0.9,5 9.3,4.4 9.3,4.4"
6859 class="st148"
6860 inkscape:label="carnitineAcylTransferaseI"
6861 inkscape:connector-curvature="0"
6862 id="R_carnitineAcylTransferaseI" /><path
6863 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6864 d="m 1567.3,933.41855 c -2,-6.9 -2,-6.9 -2,-6.9 l -2.4,6.8 2.2,-1.7 2.2,1.8 z m 7.4,8.6 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
6865 class="st32"
6866 inkscape:label="carnitineAcylTransferaseI b"
6867 inkscape:connector-curvature="0"
6868 id="B_carnitineAcylTransferaseI" /><path
6869 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6870 d="m 1567.3,956.01855 c -2,6.9 -2,6.9 -2,6.9 l -2.4,-6.8 2.2,1.7 2.2,-1.8 z m 7.4,-3.5 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
6871 class="st32"
6872 inkscape:label="carnitineAcylTransferaseI f"
6873 inkscape:connector-curvature="0"
6874 id="F_carnitineAcylTransferaseI" /><text
6875 style="font-size:16px;font-family:Calibri-Bold"
6876 id="text1816"
6877 class="st15 st16"
6878 x="1509.2845"
6879 y="977.52167">PalmCarnitine</text>
6880 <path
6881 style="fill:none;stroke:#000000;stroke-width:2.56680012"
6882 d="m 1477.7,972.41855 c 5.3,-1.5 4.6,-15.8 4.6,-15.8 m -29,0 c -2.5,10 3.7,16.2 3.7,16.2 m -18.4,0.1 c 58.9,0 58.9,0 58.9,0"
6883 class="st169"
6884 inkscape:label="translocase"
6885 inkscape:connector-curvature="0"
6886 id="R_translocase" /><path
6887 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6888 d="m 1483.8,956.91855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -43.4,14 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z"
6889 class="st32"
6890 inkscape:label="translocase f"
6891 inkscape:connector-curvature="0"
6892 id="F_translocase" /><path
6893 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6894 d="m 1454.7,956.91855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 40.6,13.9 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z"
6895 class="st32"
6896 inkscape:connector-curvature="0"
6897 id="path3243" /><text
6898 style="font-size:10px;font-family:Calibri"
6899 id="text1821"
6900 class="st17 st18"
6901 x="1476.4476"
6902 y="948.5647">carnitine</text>
6903 <text
6904 style="font-size:10px;font-family:Calibri"
6905 id="text1823"
6906 class="st17 st18"
6907 x="1425.4476"
6908 y="948.5647">carnitine</text>
6909 <text
6910 style="font-size:16px;font-family:Calibri-Bold"
6911 id="text1825"
6912 class="st15 st16"
6913 x="1333.4193"
6914 y="977.16138">PalmCarnitine</text>
6915 <path
6916 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6917 d="m 1315.8,962.01855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 3.6,7.4 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z"
6918 class="st32"
6919 inkscape:connector-curvature="0"
6920 id="path3291" /><path
6921 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6922 d="m 1305.3,962.01855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -8.5,7.4 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z"
6923 class="st32"
6924 inkscape:label="carnitineAcylTransferaseII f"
6925 inkscape:connector-curvature="0"
6926 id="F_carnitineAcylTransferaseII" /><path
6927 style="fill:none;stroke:#000000;stroke-width:2.44919991"
6928 d="m 1309.9,971.31855 c 5,-0.9 4.4,-9.3 4.4,-9.3 m -10.6,-0.1 c -2.4,5.9 3.6,9.5 3.6,9.5 m -12,0 c 24.9,0 24.9,0 24.9,0"
6929 class="st32"
6930 inkscape:label="carnitineAcylTransferaseII "
6931 inkscape:connector-curvature="0"
6932 id="R_carnitineAcylTransferaseII" /><text
6933 style="font-size:10px;font-family:Calibri"
6934 id="text1830"
6935 class="st17 st18"
6936 x="1311.5248"
6937 y="953.61157">CoA</text>
6938 <text
6939 style="font-size:10px;font-family:Calibri"
6940 id="text1832"
6941 class="st17 st18"
6942 x="1271.8422"
6943 y="952.50116">carnitine</text>
6944 <text
6945 style="font-size:16px;font-family:Calibri-Bold"
6946 id="text1834"
6947 class="st15 st16"
6948 x="1222.6273"
6949 y="976.7356">PalmCoA</text>
6950 <text
6951 style="font-size:10px;font-family:Calibri"
6952 id="text1836"
6953 class="st17 st18"
6954 x="1206.2504"
6955 y="990.83716">7 CoA</text>
6956 <text
6957 style="font-size:10px;font-family:Calibri"
6958 id="text1838"
6959 class="st17 st18"
6960 x="1171.7504"
6961 y="990.83716">7 NAD</text>
6962 <text
6963 style="font-size:10px;font-family:Calibri"
6964 id="text1840"
6965 class="st17 st18"
6966 x="1141.7504"
6967 y="990.83716">7 FAD</text>
6968 <text
6969 style="font-size:10px;font-family:Calibri"
6970 id="text1842"
6971 class="st17 st18"
6972 x="1110.2504"
6973 y="990.83716">7 H</text>
6974 <text
6975 style="font-size:6.09369993px;font-family:Calibri"
6976 id="text1844"
6977 class="st17 st26"
6978 x="1123.809"
6979 y="992.83716">2</text>
6980 <text
6981 style="font-size:10px;font-family:Calibri"
6982 id="text1846"
6983 class="st17 st18"
6984 x="1126.8978"
6985 y="990.83716">O</text>
6986 <text
6987 style="font-size:10px;font-family:Calibri"
6988 id="text1848"
6989 class="st17 st18"
6990 x="1165.7504"
6991 y="951.83716">7 NADH</text>
6992 <text
6993 style="font-size:10px;font-family:Calibri"
6994 id="text1850"
6995 class="st17 st18"
6996 x="1128.2504"
6997 y="951.83716">7 FADH</text>
6998 <text
6999 style="font-size:6.09369993px;font-family:Calibri"
7000 id="text1852"
7001 class="st17 st26"
7002 x="1157.7816"
7003 y="953.83716">2</text>
7004 <text
7005 style="font-size:10px;font-family:Calibri"
7006 id="text1854"
7007 class="st17 st18"
7008 x="1105.7504"
7009 y="951.83716">7 H</text>
7010 <path
7011 style="fill:none;stroke:#000000;stroke-width:1.93280005"
7012 d="m 1120.2,971.91855 c -5.6,-1.9 -4.1,-12.1 -4.1,-12.1 m 35.6,12.1 c -5.6,-1.9 -4.1,-12.1 -4.1,-12.1 m 35.6,12.1 c -5.6,-1.9 -4.1,-12.1 -4.1,-12.1 m -58.4,11.7 c 5.6,1.5 5.5,11.8 5.5,11.8 m 24.5,-11.8 c 5.6,1.5 5.5,11.8 5.5,11.8 m 29,-11.8 c 5.6,1.5 5.5,11.8 5.5,11.8 m 13.9,-12.1 c 5.6,1.5 5.5,11.8 5.5,11.8 m 10.1,-11.6 -112,0.1"
7013 class="st170"
7014 inkscape:label="betaOxidation "
7015 inkscape:connector-curvature="0"
7016 id="R_betaOxidation" /><path
7017 style="fill:none;stroke:#000000;stroke-width:2.44919991"
7018 d="m 1109.3,969.41855 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z m 8.5,-8.8 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 31.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 31.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z"
7019 class="st32"
7020 inkscape:label="betaOxidation f"
7021 inkscape:connector-curvature="0"
7022 id="F_betaOxidation" /><text
7023 style="font-size:16px;font-family:Calibri-Bold"
7024 id="text1858"
7025 class="st15 st16"
7026 x="1042.6273"
7027 y="976.7356">8 AcCoA</text>
7028 <path
7029 style="fill:none;stroke:#000000;stroke-width:2.44919991"
7030 d="m 1567.3,874.91855 c -2,-6.9 -2,-6.9 -2,-6.9 l -2.4,6.8 2.2,-1.7 2.2,1.8 z m 7.4,8.6 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
7031 class="st32"
7032 inkscape:label="palmitateActivation b"
7033 inkscape:connector-curvature="0"
7034 id="B_palmitateActivation" /><text
7035 style="font-size:16px;font-family:Calibri-Bold"
7036 id="text1861"
7037 class="st15 st16"
7038 x="1486.4927"
7039 y="427.78244">ATP</text>
7040 <text
7041 style="font-size:16px;font-family:Calibri-Bold"
7042 id="text1863"
7043 class="st15 st16"
7044 x="1554.2847"
7045 y="427.81766">ADP</text>
7046 <path
7047 style="fill:none;stroke:#000000;stroke-width:1.80649996"
7048 d="m 1544.5,425.81855 -33.9,-0.3"
7049 class="st116"
7050 inkscape:label="ATPmaintenance "
7051 inkscape:connector-curvature="0"
7052 id="R_ATPmaintenance" /><path
7053 style="fill:none;stroke:#000000;stroke-width:2.5"
7054 d="m 1543.5,427.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
7055 class="st22"
7056 inkscape:label="ATPmaintenancef"
7057 inkscape:connector-curvature="0"
7058 id="F_ATPmaintenance" /><text
7059 style="font-size:14px;font-family:Calibri-Bold"
7060 id="text1867"
7061 class="st15 st38"
7062 x="259.638"
7063 y="851.84009">Pi</text>
7064 <text
7065 style="font-size:16px;font-family:Calibri-Bold"
7066 id="text1869"
7067 class="st15 st16"
7068 x="278.91238"
7069 y="912.47101">Orn</text>
7070 <path
7071 style="fill:none;stroke:#000000;stroke-width:3.19709992"
7072 d="m 237.8,908.91855 c -6,-8.4 -6,-12.6 -6.6,-16.9 m 29,16.8 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 11.2,13.9 -60.2,-0.3"
7073 class="st171"
7074 inkscape:label="UniportOrnithine"
7075 inkscape:connector-curvature="0"
7076 id="R_UniportOrnithine" /><path
7077 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7078 d="m 267.4,895.31855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 l 0,0 z"
7079 class="st140"
7080 inkscape:label="UniportOrnithine f"
7081 inkscape:connector-curvature="0"
7082 id="F_UniportOrnithine" /><text
7083 style="font-size:14px;font-family:Calibri-Bold"
7084 id="text1873"
7085 class="st15 st38"
7086 x="261.46759"
7087 y="887.15851">H</text>
7088 <text
7089 style="font-size:14px;font-family:Calibri-Bold"
7090 id="text1875"
7091 class="st15 st38"
7092 x="226.01099"
7093 y="888.6438">H</text>
7094 <text
7095 style="font-size:16px;font-family:Calibri-Bold"
7096 id="text1877"
7097 class="st15 st16"
7098 x="180.79909"
7099 y="912.72589">Orn</text>
7100 <text
7101 style="font-size:16px;font-family:Calibri-Bold"
7102 id="text1879"
7103 class="st15 st16"
7104 x="303.034"
7105 y="950.73657">Orn</text>
7106 <text
7107 style="font-size:16px;font-family:Calibri-Bold"
7108 id="text1881"
7109 class="st15 st16"
7110 x="170.7791"
7111 y="950.48169">Orn</text>
7112 <path
7113 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7114 d="m 283.9,934.31855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -50,2.4 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m -26.6,8.8 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
7115 class="st140"
7116 inkscape:connector-curvature="0"
7117 id="path3519" /><path
7118 style="fill:none;stroke:#000000;stroke-width:2.82299995"
7119 d="m 218.4,948.01855 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 65.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -43.2,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 29.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
7120 class="st45"
7121 inkscape:label="CotraspArgOrnA"
7122 inkscape:connector-curvature="0"
7123 id="R_CotraspArgOrnA" /><path
7124 style="fill:none;stroke:#000000;stroke-width:2.35560012"
7125 d="m 214.4,936.71855 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 76.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -23.1,-15.5 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
7126 class="st46"
7127 inkscape:label="CotraspArgOrnA f"
7128 inkscape:connector-curvature="0"
7129 id="F_CotraspArgOrnA" /><text
7130 style="font-size:14px;font-family:Calibri-Bold"
7131 id="text1886"
7132 class="st15 st38"
7133 x="259.9368"
7134 y="926.9231">H</text>
7135 <text
7136 style="font-size:14px;font-family:Calibri-Bold"
7137 id="text1888"
7138 class="st15 st38"
7139 x="226.01099"
7140 y="927.6438">H</text>
7141 <text
7142 style="font-size:14px;font-family:Calibri-Bold"
7143 id="text1890"
7144 class="st15 st38"
7145 x="199.5208"
7146 y="926.62427">Arg</text>
7147 <text
7148 style="font-size:14px;font-family:Calibri-Bold"
7149 id="text1892"
7150 class="st15 st38"
7151 x="273.05161"
7152 y="926.62427">Arg</text>
7153 <text
7154 style="font-size:16px;font-family:Calibri-Bold"
7155 id="text1894"
7156 class="st15 st16"
7157 x="300.10669"
7158 y="992.00116">Orn</text>
7159 <text
7160 style="font-size:16px;font-family:Calibri-Bold"
7161 id="text1896"
7162 class="st15 st16"
7163 x="176.7791"
7164 y="991.49146">Orn</text>
7165 <path
7166 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7167 d="m 289.9,974.81855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -76.6,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z m 60.1,-11.2 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
7168 class="st140"
7169 inkscape:label="CotraspArgOrnB f"
7170 inkscape:connector-curvature="0"
7171 id="F_CotraspArgOrnB" /><path
7172 style="fill:none;stroke:#000000;stroke-width:3.13730001"
7173 d="m 227.1,988.41855 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 62.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -41.5,14 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 27.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
7174 class="st172"
7175 inkscape:label="CotraspArgOrnB"
7176 inkscape:connector-curvature="0"
7177 id="R_CotraspArgOrnB" /><text
7178 style="font-size:14px;font-family:Calibri-Bold"
7179 id="text1900"
7180 class="st15 st38"
7181 x="265.9368"
7182 y="967.4231">H</text>
7183 <text
7184 style="font-size:14px;font-family:Calibri-Bold"
7185 id="text1902"
7186 class="st15 st38"
7187 x="232.01099"
7188 y="968.1438">H</text>
7189 <text
7190 style="font-size:14px;font-family:Calibri-Bold"
7191 id="text1904"
7192 class="st15 st38"
7193 x="205.5208"
7194 y="967.12427">Arg</text>
7195 <text
7196 style="font-size:14px;font-family:Calibri-Bold"
7197 id="text1906"
7198 class="st15 st38"
7199 x="279.05161"
7200 y="967.12427">Arg</text>
7201 <text
7202 style="font-size:16px;font-family:Calibri-Bold"
7203 id="text1908"
7204 class="st15 st16"
7205 x="303.034"
7206 y="1030.2366">Ci</text>
7207 <text
7208 style="font-size:16px;font-family:Calibri-Bold"
7209 id="text1910"
7210 class="st15 st16"
7211 x="182.74879"
7212 y="1032.5325">Ci</text>
7213 <path
7214 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7215 d="m 283.9,1013.8186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -50,2.4 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m -26.6,8.8 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
7216 class="st140"
7217 inkscape:label="CotraspArgCitrA b"
7218 inkscape:connector-curvature="0"
7219 id="B_CotraspArgCitrA" /><path
7220 style="fill:none;stroke:#000000;stroke-width:2.82299995"
7221 d="m 218.4,1027.5186 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 65.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -43.2,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 29.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
7222 class="st45"
7223 inkscape:label="CotraspArgCitrA"
7224 inkscape:connector-curvature="0"
7225 id="R_CotraspArgCitrA" /><path
7226 style="fill:none;stroke:#000000;stroke-width:2.35560012"
7227 d="m 214.4,1016.2186 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 76.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -23.1,-15.5 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
7228 class="st46"
7229 inkscape:label="CotraspArgCitrA f"
7230 inkscape:connector-curvature="0"
7231 id="F_CotraspArgCitrA" /><text
7232 style="font-size:14px;font-family:Calibri-Bold"
7233 id="text1915"
7234 class="st15 st38"
7235 x="259.9368"
7236 y="1006.4231">H</text>
7237 <text
7238 style="font-size:14px;font-family:Calibri-Bold"
7239 id="text1917"
7240 class="st15 st38"
7241 x="226.01099"
7242 y="1007.1438">H</text>
7243 <text
7244 style="font-size:14px;font-family:Calibri-Bold"
7245 id="text1919"
7246 class="st15 st38"
7247 x="199.5208"
7248 y="1006.1243">Arg</text>
7249 <text
7250 style="font-size:14px;font-family:Calibri-Bold"
7251 id="text1921"
7252 class="st15 st38"
7253 x="273.05161"
7254 y="1006.1243">Arg</text>
7255 <path
7256 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7257 d="m 282.4,1048.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -76.6,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z m 60.1,-11.2 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
7258 class="st140"
7259 inkscape:label="CotraspArgCitrB f"
7260 inkscape:connector-curvature="0"
7261 id="F_CotraspArgCitrB" /><path
7262 style="fill:none;stroke:#000000;stroke-width:3.13730001"
7263 d="m 219.6,1061.9186 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 62.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -41.5,14 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 27.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
7264 class="st172"
7265 inkscape:label="CotraspArgCitrB"
7266 inkscape:connector-curvature="0"
7267 id="R_CotraspArgCitrB" /><text
7268 style="font-size:14px;font-family:Calibri-Bold"
7269 id="text1925"
7270 class="st15 st38"
7271 x="258.4368"
7272 y="1040.9231">H</text>
7273 <text
7274 style="font-size:14px;font-family:Calibri-Bold"
7275 id="text1927"
7276 class="st15 st38"
7277 x="224.51099"
7278 y="1041.6438">H</text>
7279 <text
7280 style="font-size:14px;font-family:Calibri-Bold"
7281 id="text1929"
7282 class="st15 st38"
7283 x="198.0208"
7284 y="1040.6243">Arg</text>
7285 <text
7286 style="font-size:14px;font-family:Calibri-Bold"
7287 id="text1931"
7288 class="st15 st38"
7289 x="271.55161"
7290 y="1040.6243">Arg</text>
7291 <text
7292 style="font-size:16px;font-family:Calibri-Bold"
7293 id="text1933"
7294 class="st15 st16"
7295 x="292.57349"
7296 y="1066.5403">Ci</text>
7297 <text
7298 style="font-size:16px;font-family:Calibri-Bold"
7299 id="text1935"
7300 class="st15 st16"
7301 x="182.74879"
7302 y="1067.0325">Ci</text>
7303 <text
7304 style="font-size:16px;font-family:Calibri-Bold"
7305 id="text1937"
7306 class="st15 st16"
7307 x="289.01248"
7308 y="1101.4709">Arg</text>
7309 <path
7310 style="fill:none;stroke:#000000;stroke-width:3.19709992"
7311 d="m 237.8,1097.9186 c -6,-8.4 -6,-12.6 -6.6,-16.9 m 29,16.8 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 11.2,13.9 -60.2,-0.3"
7312 class="st171"
7313 inkscape:label="UniportArginine"
7314 inkscape:connector-curvature="0"
7315 id="R_UniportArginine" /><path
7316 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7317 d="m 267.4,1084.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
7318 class="st140"
7319 inkscape:label="UniportArginine f"
7320 inkscape:connector-curvature="0"
7321 id="F_UniportArginine" /><text
7322 style="font-size:14px;font-family:Calibri-Bold"
7323 id="text1941"
7324 class="st15 st38"
7325 x="261.46759"
7326 y="1076.1584">H</text>
7327 <text
7328 style="font-size:14px;font-family:Calibri-Bold"
7329 id="text1943"
7330 class="st15 st38"
7331 x="226.01099"
7332 y="1077.6438">H</text>
7333 <text
7334 style="font-size:16px;font-family:Calibri-Bold"
7335 id="text1945"
7336 class="st15 st16"
7337 x="180.79909"
7338 y="1101.7258">Arg</text>
7339 <text
7340 style="font-size:16px;font-family:Calibri-Bold"
7341 id="text1947"
7342 class="st15 st16"
7343 x="295.41238"
7344 y="1140.4709">Ci</text>
7345 <path
7346 style="fill:none;stroke:#000000;stroke-width:3.19709992"
7347 d="m 246.8,1136.9186 c -6,-8.4 -6,-12.6 -6.6,-16.9 m 29,16.8 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 11.2,13.9 -60.2,-0.3"
7348 class="st171"
7349 inkscape:label="UniportCitrulline"
7350 inkscape:connector-curvature="0"
7351 id="R_UniportCitrulline" /><path
7352 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7353 d="m 276.4,1123.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
7354 class="st140"
7355 inkscape:label="UniportCitrulline f"
7356 inkscape:connector-curvature="0"
7357 id="F_UniportCitrulline" /><text
7358 style="font-size:14px;font-family:Calibri-Bold"
7359 id="text1951"
7360 class="st15 st38"
7361 x="270.46759"
7362 y="1115.1584">H</text>
7363 <text
7364 style="font-size:14px;font-family:Calibri-Bold"
7365 id="text1953"
7366 class="st15 st38"
7367 x="235.37189"
7368 y="1114.1194">H</text>
7369 <text
7370 style="font-size:16px;font-family:Calibri-Bold"
7371 id="text1955"
7372 class="st15 st16"
7373 x="202.06329"
7374 y="1141.4475">Ci</text>
7375 <path
7376 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7377 d="m 275.3,1099.8186 c 2.4,-0.8 4.8,-1.6 7.2,-2.4 -2.5,-0.6 -4.9,-1.3 -7.4,-1.9 0.6,0.7 1.3,1.4 1.9,2.1 -0.6,0.8 -1.1,1.5 -1.7,2.2 z m -40.9,-15.5 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
7378 class="st140"
7379 inkscape:label="UniportArginine b"
7380 inkscape:connector-curvature="0"
7381 id="B_UniportArginine" /><path
7382 style="fill:none;stroke:#000000;stroke-width:2.32780004"
7383 d="m 243,1123.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.7,0.5 1.4,1 2.2,1.5 z m 41.3,15.5 c 2.4,-0.8 4.8,-1.6 7.2,-2.4 -2.5,-0.6 -4.9,-1.3 -7.4,-1.9 0.6,0.7 1.3,1.4 1.9,2.1 -0.6,0.8 -1.1,1.5 -1.7,2.2 z"
7384 class="st140"
7385 inkscape:label="UniportCitrulline b"
7386 inkscape:connector-curvature="0"
7387 id="B_UniportCitrulline" /><path
7388 style="fill:none;stroke:#000000;stroke-width:2.22029996"
7389 d="m 1039.7789,1224.1775 0.3,50.4"
7390 class="st68"
7391 inkscape:label="DM_10formylTHFc"
7392 inkscape:connector-curvature="0"
7393 id="R_DM_10formylTHFc" /><text
7394 style="font-size:16px;font-family:Calibri-Bold"
7395 id="text1960"
7396 class="st15 st16"
7397 x="984.76355"
7398 y="1218.4149">10-formylTHF</text>
7399 <path
7400 style="fill:none;stroke:#000000;stroke-width:2.17810011"
7401 d="m 1037.8789,1273.7775 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
7402 class="st63"
7403 inkscape:label="DM_10formylTHFc f"
7404 inkscape:connector-curvature="0"
7405 id="F_DM_10formylTHFc" /><text
7406 style="font-size:16px;font-family:Calibri-Bold"
7407 id="text1963"
7408 class="st15 st16"
7409 x="739.07251"
7410 y="1219.4495">carnitine</text>
7411 <path
7412 style="fill:none;stroke:#000000;stroke-width:2.17810011"
7413 d="m 769.6,1234.7186 0,47.6"
7414 class="st63"
7415 inkscape:label="DM_Carnitine"
7416 inkscape:connector-curvature="0"
7417 id="R_DM_Carnitine" /><path
7418 style="fill:none;stroke:#000000;stroke-width:2.17810011"
7419 d="m 769.8,1233.4186 2.2,1.8 -2.2,-7.2 -2.2,7.2 2.2,-1.8 z"
7420 class="st63"
7421 inkscape:label="DM_Carnitine f"
7422 inkscape:connector-curvature="0"
7423 id="F_DM_Carnitine" /><path
7424 style="fill:none;stroke:#000000;stroke-width:2.17810011"
7425 d="m 1382.6,1269.2186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
7426 class="st63"
7427 inkscape:label="Palmitate_DM_COOP f"
7428 inkscape:connector-curvature="0"
7429 id="F_Palmitate_DM_COOP" /><path
7430 style="fill:none;stroke:#000000;stroke-width:2.17810011"
7431 d="m 1384.7,1222.0186 0,47.6"
7432 class="st63"
7433 inkscape:label="Palmitate_DM_COOP"
7434 inkscape:connector-curvature="0"
7435 id="R_Palmitate_DM_COOP" /><text
7436 style="font-size:16px;font-family:Calibri-Bold"
7437 id="text1969"
7438 class="st15 st16"
7439 x="1377.4066"
7440 y="1218.3489">Palm</text>
7441 <path
7442 style="fill:none;stroke:#000000;stroke-width:2.18210006"
7443 d="m 1305.8,1276.7186 -0.3,-48.1"
7444 class="st14"
7445 inkscape:label="Arginine_DM_COOP"
7446 inkscape:connector-curvature="0"
7447 id="R_Arginine_DM_COOP" /><path
7448 style="fill:none;stroke:#000000;stroke-width:2.22930002"
7449 d="m 1267.8,1232.1186 2.2,-7.7 2.2,7.7 -2.2,-1.9 -2.2,1.9 z"
7450 class="st69"
7451 inkscape:label="Glutamate_DM_COOP b"
7452 inkscape:connector-curvature="0"
7453 id="B_Glutamate_DM_COOP" /><path
7454 style="fill:none;stroke:#000000;stroke-width:3.16359997"
7455 d="m 643.6,1230.3186 2.2,-6.9 2.2,6.9 -2.2,-1.7 -2.2,1.7 z"
7456 class="st65"
7457 inkscape:label="Ex_NH3 b"
7458 inkscape:connector-curvature="0"
7459 id="B_Ex_NH3" /><text
7460 style="font-size:10px;font-family:Calibri"
7461 id="text1974"
7462 class="st17 st18"
7463 x="1314.7279"
7464 y="204.19505">ATP</text>
7465 <text
7466 style="font-size:10px;font-family:Calibri"
7467 id="text1976"
7468 class="st17 st18"
7469 x="1294.9379"
7470 y="204.31226">ADP</text>
7471 <path
7472 style="fill:none;stroke:#000000;stroke-width:1.68470001"
7473 d="m 1308.1,213.31855 c -2.4,6.7 3.6,10.9 3.6,10.9 m 15.7,0.2 c -26.9,0 -26.9,0 -26.9,0 m 19.4,-11.1 c 2.4,6.7 -3.6,10.9 -3.6,10.9"
7474 class="st163"
7475 inkscape:label="AK"
7476 inkscape:connector-curvature="0"
7477 id="R_AK" /><path
7478 style="fill:none;stroke:#000000;stroke-width:2.44919991"
7479 d="m 1303.7,221.91855 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z m 1.9,-8.8 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
7480 class="st32"
7481 inkscape:label="AK b"
7482 inkscape:connector-curvature="0"
7483 id="B_AK" /><path
7484 style="fill:none;stroke:#000000;stroke-width:2.44919991"
7485 d="m 1327.4,222.21855 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z m -8.6,-9.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
7486 class="st32"
7487 inkscape:label="AK f"
7488 inkscape:connector-curvature="0"
7489 id="F_AK" /><text
7490 style="font-size:16px;font-family:Calibri-Bold"
7491 id="text1981"
7492 class="st15 st16"
7493 x="1341.2035"
7494 y="225.97145">dAMP</text>
7495 <text
7496 style="font-size:10px;font-family:Calibri"
7497 id="text1983"
7498 class="st17 st18"
7499 x="422.99298"
7500 y="130.87186">H</text>
7501 <text
7502 style="font-size:6.5px;font-family:Calibri"
7503 id="text1985"
7504 class="st17 st173"
7505 x="429.22339"
7506 y="132.87186">2</text>
7507 <text
7508 style="font-size:10px;font-family:Calibri"
7509 id="text1987"
7510 class="st17 st18"
7511 x="432.51788"
7512 y="130.87186">O</text>
7513 <text
7514 style="font-size:10px;font-family:Calibri"
7515 id="text1989"
7516 class="st17 st18"
7517 x="427.66238"
7518 y="118.75516">Pi</text>
7519 <path
7520 style="fill:none;stroke:#000000;stroke-width:2.0948"
7521 d="m 457.5,136.01855 0,-31.1 0,31.1 z m -0.4,-14.7 c -0.9,-5.5 -11.1,-5.3 -11.1,-5.3 m -3.6,11.8 c 8.8,2.9 14.6,-3.3 14.6,-3.3"
7522 class="st76"
7523 inkscape:label="G6PPer"
7524 inkscape:connector-curvature="0"
7525 id="R_G6PPer" /><path
7526 style="fill:none;stroke:#000000;stroke-width:1.87170005"
7527 d="m 447,117.71855 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z m 12.1,-10.7 c -1.7,-7.299996 -1.7,-7.299996 -1.7,-7.299996 l -1.7,7.299996 1.7,-1.8 1.7,1.8 z"
7528 class="st30"
7529 inkscape:label="F G6PPer"
7530 inkscape:connector-curvature="0"
7531 id="F_G6PPer" /><path
7532 style="fill:none;stroke:#000000;stroke-width:2.0948"
7533 d="m 457.9,245.51855 0,-31.1 0,31.1 z m -0.4,-14.8 c -0.9,-5.5 -11.1,-5.3 -11.1,-5.3 m -3.6,11.9 c 8.8,2.9 14.6,-3.3 14.6,-3.3"
7534 class="st76"
7535 inkscape:transform-center-y="-61.654422"
7536 inkscape:transform-center-x="138.9285"
7537 inkscape:connector-curvature="0"
7538 id="R_FBP" /><path
7539 style="fill:none;stroke:#000000;stroke-width:1.87170005"
7540 d="m 447.4,227.21855 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z m 12.1,-10.7 c -1.7,-7.3 -1.7,-7.3 -1.7,-7.3 l -1.7,7.3 1.7,-1.8 1.7,1.8 z"
7541 class="st30"
7542 inkscape:transform-center-y="-76.278967"
7543 inkscape:transform-center-x="138.06632"
7544 inkscape:label="FBP f"
7545 inkscape:connector-curvature="0"
7546 id="F_FBP" /><text
7547 style="font-size:10px;font-family:Calibri"
7548 id="text1995"
7549 class="st17 st18"
7550 x="424.16238"
7551 y="240.49146">H</text>
7552 <text
7553 style="font-size:6.5px;font-family:Calibri"
7554 id="text1997"
7555 class="st17 st173"
7556 x="430.39288"
7557 y="242.49146">2</text>
7558 <text
7559 style="font-size:10px;font-family:Calibri"
7560 id="text1999"
7561 class="st17 st18"
7562 x="433.6868"
7563 y="240.49146">O</text>
7564 <text
7565 style="font-size:10px;font-family:Calibri"
7566 id="text2001"
7567 class="st17 st18"
7568 x="428.83179"
7569 y="228.37425">Pi</text>
7570 <path
7571 style="fill:none;stroke:#000000;stroke-width:2.17810011"
7572 d="m 1405.8,1229.0186 0,47.6"
7573 class="st63"
7574 inkscape:label="Palmitate_UP_COOP"
7575 inkscape:connector-curvature="0"
7576 id="R_Palmitate_UP_COOP" /><path
7577 style="fill:none;stroke:#000000;stroke-width:2.18210006"
7578 d="m 1403.7,1233.9186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
7579 class="st14"
7580 inkscape:label="Palmitate_UP_COOP f"
7581 inkscape:connector-curvature="0"
7582 id="F_Palmitate_UP_COOP" /><path
7583 style="fill:none;stroke:#000000;stroke-width:2.22930002"
7584 d="m 767.6,1278.0186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
7585 class="st69"
7586 inkscape:label="DM_Carnitine b"
7587 inkscape:connector-curvature="0"
7588 id="B_DM_Carnitine" /><path
7589 style="fill:none;stroke:#000000;stroke-width:2.67510009"
7590 d="m 964.1,1232.4186 -2.2,-7.1 -2.2,7.1 2.2,-1.8 2.2,1.8 z"
7591 class="st64"
7592 inkscape:label="UptakeCitrate f"
7593 inkscape:connector-curvature="0"
7594 id="F_UptakeCitrate" /><path
7595 style="fill:none;stroke:#000000;stroke-width:2.67510009"
7596 d="m 962,1278.6186 0,-46.6"
7597 class="st64"
7598 inkscape:label="DM_Citrate"
7599 inkscape:connector-curvature="0"
7600 id="R_DM_Citrate" /><text
7601 style="font-size:16px;font-family:Calibri-Bold"
7602 id="text2008"
7603 class="st15 st16"
7604 x="952.39581"
7605 y="1218.1301">Cit</text>
7606 <path
7607 style="fill:none;stroke:#000000;stroke-width:2.22930002"
7608 d="m 959.6,1276.4186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
7609 class="st69"
7610 inkscape:label="UptakeCitrate b"
7611 inkscape:connector-curvature="0"
7612 id="B_UptakeCitrate" /><path
7613 style="fill:none;stroke:#000000;stroke-width:2.18210006"
7614 d="m 1174.9998,1273.8805 -2.1,7.3 -2.3,-7.3 2.2,1.8 2.2,-1.8 z"
7615 class="st14"
7616 inkscape:label="Glucose_DM_COOP f"
7617 inkscape:connector-curvature="0"
7618 id="F_Glucose_DM_COOP" /><path
7619 style="fill:none;stroke:#000000;stroke-width:2.22930002"
7620 d="m 1137.2,1273.5186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
7621 class="st69"
7622 inkscape:label="LactateL_DM_COOP f"
7623 inkscape:connector-curvature="0"
7624 id="F_DM_LactateL" /><path
7625 style="fill:none;stroke:#000000;stroke-width:2.22930002"
7626 d="m 1139.2,1223.4186 0,50.5"
7627 class="st69"
7628 inkscape:label="LactateL_DM_COOP"
7629 inkscape:connector-curvature="0"
7630 id="R_LactateL_DM_COOP" /><path
7631 style="fill:none;stroke:#000000;stroke-width:2.18210006"
7632 d="m 1231.89,1231.8186 2.2,-7.3 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
7633 class="st14"
7634 inkscape:label="Glutamine_DM_COOP b"
7635 inkscape:connector-curvature="0"
7636 id="B_Glutamine_DM_COOP" /><path
7637 style="fill:none;stroke:#000000;stroke-width:2.18210006"
7638 d="m 1233.89,1279.4186 0,-48"
7639 class="st14"
7640 inkscape:label="Glutamine_DM_COOP"
7641 inkscape:connector-curvature="0"
7642 id="R_Glutamine_DM_COOP" /><flowRoot
7643 xml:space="preserve"
7644 id="flowRoot5366"
7645 style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
7646 transform="translate(-20.6,18.418554)"><flowRegion
7647 id="flowRegion5368"><rect
7648 id="rect5370"
7649 width="1165.1471"
7650 height="77.465683"
7651 x="306.70087"
7652 y="-39.523308" /></flowRegion><flowPara
7653 id="flowPara5372" /></flowRoot><flowRoot
7654 xml:space="preserve"
7655 id="TitoloConfronto"
7656 style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
7657 inkscape:label="TitoloConfronto"
7658 transform="translate(-18.364224,56.426743)"><flowRegion
7659 id="flowRegion5376"><rect
7660 id="rect5378"
7661 width="1869.6877"
7662 height="68.569115"
7663 x="301.95807"
7664 y="-69.56102" /></flowRegion><flowPara
7665 id="TitleText"
7666 style="font-style:normal;font-variant:normal;font-weight:normal;font-stretch:normal;font-size:45px;font-family:sans-serif;-inkscape-font-specification:sans-serif">TITOLO: TITOLOTITOLO </flowPara></flowRoot><flowRoot
7667 xml:space="preserve"
7668 id="flowRoot5382"
7669 style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
7670 transform="translate(-16.64767,38.180207)"><flowRegion
7671 id="flowRegion5384"><rect
7672 id="rect5386"
7673 width="275.00043"
7674 height="149.79698"
7675 x="1681.3033"
7676 y="204.59315" /></flowRegion><flowPara
7677 id="flowPara5390"
7678 style="font-style:normal;font-variant:normal;font-weight:bold;font-stretch:normal;font-family:sans-serif;-inkscape-font-specification:'sans-serif Bold'">Fold Change</flowPara></flowRoot><flowRoot
7679 xml:space="preserve"
7680 id="FC_min"
7681 style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
7682 transform="translate(-8.622366,131.05768)"
7683 inkscape:label="FC_min"><flowRegion
7684 id="flowRegion5384-2"><rect
7685 id="rect5386-9"
7686 width="275.00043"
7687 height="149.79698"
7688 x="1681.3033"
7689 y="204.59315" /></flowRegion><flowPara
7690 id="Val_FC_min">min: </flowPara></flowRoot><flowRoot
7691 xml:space="preserve"
7692 id="FC_max"
7693 style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
7694 transform="translate(-17.492772,95.648076)"
7695 inkscape:label="FC_max"><flowRegion
7696 id="flowRegion5384-2-2"><rect
7697 id="rect5386-9-9"
7698 width="275.00043"
7699 height="149.79698"
7700 x="1681.3033"
7701 y="204.59315" /></flowRegion><flowPara
7702 id="Val_FC_max">max:</flowPara></flowRoot></svg>