Mercurial > repos > bimib > cobraxy
diff COBRAxy/docs/quickstart.md @ 542:fcdbc81feb45 draft
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| author | francesco_lapi |
|---|---|
| date | Sun, 26 Oct 2025 19:27:41 +0000 |
| parents | 4ed95023af20 |
| children |
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--- a/COBRAxy/docs/quickstart.md Sat Oct 25 15:20:55 2025 +0000 +++ b/COBRAxy/docs/quickstart.md Sun Oct 26 19:27:41 2025 +0000 @@ -38,7 +38,8 @@ ```bash # Generate RAS scores using built-in ENGRO2 model -ras_generator -td $(pwd) \ +# Note: -td is optional and auto-detected after pip install +ras_generator \ -in sample_expression.tsv \ -ra ras_scores.tsv \ -rs ENGRO2 @@ -61,7 +62,8 @@ ```bash # Create pathway maps with statistical analysis -marea -td $(pwd) \ +# Note: -td is optional and auto-detected after pip install +marea \ -using_RAS true \ -input_data ras_scores.tsv \ -choice_map ENGRO2 \ @@ -95,20 +97,19 @@ ### Learn More About the Analysis -- **[Understanding RAS](tools/ras-generator.md)** - How activity scores are computed -- **[MAREA Analysis](tools/marea.md)** - Statistical enrichment methods +- **[Understanding RAS](/tools/ras-generator.md)** - How activity scores are computed +- **[MAREA Analysis](/tools/marea.md)** - Statistical enrichment methods - **[Data Flow](getting-started.md#analysis-workflows)** - Complete workflow overview ### Try Advanced Features - **[Flux Sampling](tutorials/workflow.md#flux-simulation-workflow)** - Predict metabolic flux distributions -- **[Python API](tutorials/python-api.md)** - Integrate into scripts and pipelines -- **[Galaxy Interface](tutorials/galaxy-setup.md)** - Web-based analysis +- **[Galaxy Interface](/tutorials/galaxy-setup.md)** - Web-based analysis ### Use Your Own Data -- **[Data Formats](tutorials/data-formats.md)** - Prepare your expression data -- **[Troubleshooting](troubleshooting.md)** - Common issues and solutions +- **[Data Formats](/tutorials/data-formats.md)** - Prepare your expression data +- **[Troubleshooting](/troubleshooting.md)** - Common issues and solutions ## Complete Example Pipeline @@ -124,8 +125,9 @@ EOF # Run analysis pipeline -ras_generator -td /path/to/COBRAxy -in expression.tsv -ra ras.tsv -rs ENGRO2 -marea -td /path/to/COBRAxy -using_RAS true -input_data ras.tsv -choice_map ENGRO2 -gs true -idop maps +# Note: -td is optional and auto-detected after pip install +ras_generator -in expression.tsv -ra ras.tsv -rs ENGRO2 +marea -using_RAS true -input_data ras.tsv -choice_map ENGRO2 -gs true -idop maps # View results ls maps/*.svg @@ -138,16 +140,4 @@ 1. **Check Prerequisites**: Ensure COBRAxy is properly installed 2. **Verify File Format**: Make sure your data is tab-separated TSV 3. **Review Logs**: Look for error messages in the terminal output -4. **Consult Guides**: [Troubleshooting](troubleshooting.md) and [Installation](installation.md) - -**Still stuck?** Ask for help in [GitHub Discussions](https://github.com/CompBtBs/COBRAxy/discussions). - -## Summary - -🎉 **Congratulations!** You've completed your first COBRAxy analysis. You now know how to: - -- ✅ Generate metabolic activity scores from gene expression -- ✅ Create statistical pathway visualizations -- ✅ Interpret basic COBRAxy outputs - -Ready for more? Explore the [full documentation](/) to unlock COBRAxy's complete potential! \ No newline at end of file +4. **Consult Guides**: [Troubleshooting](/troubleshooting.md) and [Installation](/installation.md) \ No newline at end of file
