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      </unitDefinition>
    </listOfUnitDefinitions>
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      <species metaid="meta_M_M01067_c" sboTerm="SBO:0000299" id="M_M01067_c" name="5Alpha-Cholesta-8,24-Dien-3-One" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C27H42O"/>
      <species metaid="meta_M_zymst_c" sboTerm="SBO:0000299" id="M_zymst_c" name="Zymosterol C27H44O" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C27H44O"/>
      <species metaid="meta_M_chlstol_c" sboTerm="SBO:0000299" id="M_chlstol_c" name="5alpha-Cholesta-7,24-dien-3beta-ol" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C27H44O"/>
      <species metaid="meta_M_ddsmsterol_c" sboTerm="SBO:0000299" id="M_ddsmsterol_c" name="7-Dehydrodesmosterol" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C27H42O"/>
      <species metaid="meta_M_dsmsterol_c" sboTerm="SBO:0000299" id="M_dsmsterol_c" name="Desmosterol; 3beta-cholesta-5,24-dien-3-ol" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C27H44O"/>
      <species metaid="meta_M_R_3_hydroxybutanoyl_ACP_c" sboTerm="SBO:0000299" id="M_R_3_hydroxybutanoyl_ACP_c" name="R_3_hydroxybutanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_but_2_enoyl_ACP_c" sboTerm="SBO:0000299" id="M_but_2_enoyl_ACP_c" name="but_2_enoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_butyryl_ACP_c" sboTerm="SBO:0000299" id="M_butyryl_ACP_c" name="butyryl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_3_oxohexanoyl_ACP_c" sboTerm="SBO:0000299" id="M_3_oxohexanoyl_ACP_c" name="3_oxohexanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_D_3_hydroxyhexanoyl_ACP_c" sboTerm="SBO:0000299" id="M_D_3_hydroxyhexanoyl_ACP_c" name="D_3_hydroxyhexanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_2E_hexenoyl_ACP_c" sboTerm="SBO:0000299" id="M_2E_hexenoyl_ACP_c" name="2E_hexenoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_hexanoyl_ACP_c" sboTerm="SBO:0000299" id="M_hexanoyl_ACP_c" name="hexanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_3_oxooctanoyl_ACP_c" sboTerm="SBO:0000299" id="M_3_oxooctanoyl_ACP_c" name="3_oxooctanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_R_3_hydroxyoctanoyl_ACP_c" sboTerm="SBO:0000299" id="M_R_3_hydroxyoctanoyl_ACP_c" name="R_3_hydroxyoctanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_2E_octenoyl_ACP_c" sboTerm="SBO:0000299" id="M_2E_octenoyl_ACP_c" name="2E_octenoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_octanoyl_ACP_c" sboTerm="SBO:0000299" id="M_octanoyl_ACP_c" name="octanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_3_oxodecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_3_oxodecanoyl_ACP_c" name="3_oxodecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_R_3_hydroxydecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_R_3_hydroxydecanoyl_ACP_c" name="R_3_hydroxydecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_2E_decenoyl_ACP_c" sboTerm="SBO:0000299" id="M_2E_decenoyl_ACP_c" name="2E_decenoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_decanoyl_ACP_c" sboTerm="SBO:0000299" id="M_decanoyl_ACP_c" name="decanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_3_oxododecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_3_oxododecanoyl_ACP_c" name="3_oxododecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_D_3_hydroxydodecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_D_3_hydroxydodecanoyl_ACP_c" name="D_3_hydroxydodecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_2E_dodecenoyl_ACP_c" sboTerm="SBO:0000299" id="M_2E_dodecenoyl_ACP_c" name="2E_dodecenoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_dodecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_dodecanoyl_ACP_c" name="dodecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_3_oxotetradecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_3_oxotetradecanoyl_ACP_c" name="3_oxotetradecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_HMA_c" sboTerm="SBO:0000299" id="M_HMA_c" name="HMA" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_2E_tetradecenoyl_ACP_c" sboTerm="SBO:0000299" id="M_2E_tetradecenoyl_ACP_c" name="2E_tetradecenoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_tetradecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_tetradecanoyl_ACP_c" name="tetradecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_3_oxohexadecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_3_oxohexadecanoyl_ACP_c" name="3_oxohexadecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_R_3_hydroxypalmitoyl_ACP_c" sboTerm="SBO:0000299" id="M_R_3_hydroxypalmitoyl_ACP_c" name="R_3_hydroxypalmitoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_2E_hexadecenoyl_ACP_c" sboTerm="SBO:0000299" id="M_2E_hexadecenoyl_ACP_c" name="2E_hexadecenoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_hexadecanoyl_ACP_c" sboTerm="SBO:0000299" id="M_hexadecanoyl_ACP_c" name="hexadecanoyl_ACP" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_ala_B_e" sboTerm="SBO:0000299" id="M_ala_B_e" name="bAla" compartment="C_e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_thymd_e" sboTerm="SBO:0000299" id="M_thymd_e" name="Thymidine" compartment="C_e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_thymd_c" sboTerm="SBO:0000299" id="M_thymd_c" name="Thymidine" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_HC00576_e" sboTerm="SBO:0000299" id="M_HC00576_e" name="HC00576" compartment="C_e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species metaid="meta_M_4abut_e" sboTerm="SBO:0000299" id="M_4abut_e" name="4abut" compartment="C_e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
      <species id="M_chsterol_e" name="Cholesterol" compartment="C_e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C27H46O"/>
      <species id="M_gal_e" name="D-Galactose" compartment="C_e" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C6H12O6"/>
      <species id="M_gal_c" name="D-Galactose" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C6H12O6"/>
      <species id="M_gal1p_c" name="D-galactopyranose 1-phosphate" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C6H11O9P"/>
      <species id="M_udpg_c" name="Uridine diphosphate glucose" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C15H22N2O17P2"/>
      <species id="M_g1p_c" name="Glucose 1-phosphate" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C6H11O9P"/>
      <species id="M_udpgal_c" name="Uridine diphosphategalactose" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C6H11O9P"/>
      <species id="M_ac_c" name="Acetic acid" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C2H3O2"/>
      <species id="M_acrn_c" name="Carnitine O-Acetyltransferase" compartment="C_c" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C9H17NO4"/>
      <species id="M_acrn_m" name="Carnitine O-Acetyltransferase" compartment="C_m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0" fbc:chemicalFormula="C9H17NO4"/>
      <species id="M_ac_m" compartment="C_m" hasOnlySubstanceUnits="false" boundaryCondition="false" constant="false" fbc:charge="0"/>
    </listOfSpecies>
    <listOfParameters>
      <parameter sboTerm="SBO:0000626" id="cobra_default_lb" value="-1000" constant="true"/>
      <parameter sboTerm="SBO:0000626" id="cobra_default_ub" value="1000" constant="true"/>
      <parameter sboTerm="SBO:0000626" id="cobra_0_bound" value="0" constant="true"/>
      <parameter sboTerm="SBO:0000626" id="minus_inf" value="-INF" constant="true"/>
      <parameter sboTerm="SBO:0000626" id="plus_inf" value="INF" constant="true"/>
    </listOfParameters>
    <listOfReactions>
      <reaction metaid="meta_R_EX_lac__L_e" sboTerm="SBO:0000627" id="R_EX_lac__L_e" name="EX_lactatex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-lactate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_lac__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-lactate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_lac__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_glc__D_e" sboTerm="SBO:0000627" id="R_EX_glc__D_e" name="EX_glucosex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;D-glycime exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_glc__D_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/D-glycime exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glc__D_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_glu__L_e" sboTerm="SBO:0000627" id="R_EX_glu__L_e" name="EX_glutamateINx" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-glutamate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_glu__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-glutamate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_gln__L_e" sboTerm="SBO:0000627" id="R_EX_gln__L_e" name="EX_glutaminex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-glycine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_gln__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-glycine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gln__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_asp__L_e" sboTerm="SBO:0000627" id="R_EX_asp__L_e" name="EX_aspartatex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-aspartate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_asp__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-aspartate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asp__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_co2_e" sboTerm="SBO:0000627" id="R_EX_co2_e" name="EX_CO2x" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;CO2 exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_co2_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/CO2 exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_co2_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_h_e" sboTerm="SBO:0000627" id="R_EX_h_e" name="EX_Hx" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;H exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_h_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/H exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_h2o_e" sboTerm="SBO:0000627" id="R_EX_h2o_e" name="EX_H2Ox" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;H2O exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_h2o_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/H2O exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_pi_e" sboTerm="SBO:0000627" id="R_EX_pi_e" name="EX_Pix" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Phosphate exchange &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_pi_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Phosphate exchange "/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_nh4_e" sboTerm="SBO:0000627" id="R_EX_nh4_e" name="EX_NH3x" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;NH4 exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_nh4_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/NH4 exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_nh4_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_o2_e" sboTerm="SBO:0000627" id="R_EX_o2_e" name="EX_O2x" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;O2 exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_o2_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/O2 exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_o2_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_arg__L_e" sboTerm="SBO:0000627" id="R_EX_arg__L_e" name="EX_argininex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-arginine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_arg__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-arginine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_arg__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_pro__L_e" sboTerm="SBO:0000627" id="R_EX_pro__L_e" name="EX_prolinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-proline exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_pro__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-proline exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_pro__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_leu__L_e" sboTerm="SBO:0000627" id="R_EX_leu__L_e" name="EX_leucinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-leucine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_leu__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-leucine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_leu__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_ile__L_e" sboTerm="SBO:0000627" id="R_EX_ile__L_e" name="EX_isoleucinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-isoleucine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_ile__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-isoleucine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ile__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_met__L_e" sboTerm="SBO:0000627" id="R_EX_met__L_e" name="EX_methionine" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-methionine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_met__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-methionine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_met__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_gly_e" sboTerm="SBO:0000627" id="R_EX_gly_e" name="EX_glycinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_gly_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gly_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_phe__L_e" sboTerm="SBO:0000627" id="R_EX_phe__L_e" name="EX_phenylalaninex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-pheninaline exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_phe__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-pheninaline exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_phe__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_ser__L_e" sboTerm="SBO:0000627" id="R_EX_ser__L_e" name="EX_serinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-serine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_ser__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-serine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ser__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_ala__L_e" sboTerm="SBO:0000627" id="R_EX_ala__L_e" name="EX_alaninex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-alanine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_ala__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-alanine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ala__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_asn__L_e" sboTerm="SBO:0000627" id="R_EX_asn__L_e" name="EX_asparaginex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-asparagine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_asn__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-asparagine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asn__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_fol_e" sboTerm="SBO:0000627" id="R_EX_fol_e" name="EX_folatex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_fol_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fol_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_urea_e" sboTerm="SBO:0000627" id="R_EX_urea_e" name="EX_ureax" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_urea_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_urea_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_pyr_e" sboTerm="SBO:0000627" id="R_EX_pyr_e" name="EX_pyruvatex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvat exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_pyr_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pyruvat exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_pyr_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_PYRt2" sboTerm="SBO:0000176" id="R_PYRt2" name="Pyruvate transport in via proton symport" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PYRt2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_e" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10928"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10924"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10922"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_EX_gudac_e" sboTerm="SBO:0000627" id="R_EX_gudac_e" name="EX_guanidinoacetatex" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Guanidinoacetic acid exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_gudac_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Guanidinoacetic acid exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gudac_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_hdca_e" sboTerm="SBO:0000627" id="R_EX_hdca_e" name="EX_palmitatex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Hexadecanoate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_hdca_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Hexadecanoate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_hdca_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_ptrc_e" sboTerm="SBO:0000627" id="R_EX_ptrc_e" name="EX_putrescinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Putrescine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_ptrc_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Putrescine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ptrc_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_biomassx" sboTerm="SBO:0000627" id="R_EX_biomassx" name="EX_biomassx" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Biomass exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_biomassx">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Biomass exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_BIOMASSA_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_gthox_e" sboTerm="SBO:0000627" id="R_EX_gthox_e" name="EX_GSSGx" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidized glutathione exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_gthox_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Oxidized glutathione exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gthox_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_2obut_e" sboTerm="SBO:0000627" id="R_EX_2obut_e" name="EX_2oxobutyratex" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;2-Oxobutanoate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_2obut_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/2-Oxobutanoate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2obut_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_val__L_e" sboTerm="SBO:0000627" id="R_EX_val__L_e" name="EX_valinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-valine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_val__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-valine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_val__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_spmd_e" sboTerm="SBO:0000627" id="R_EX_spmd_e" name="EX_spermidinex" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Spermidine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_spmd_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Spermidine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_spmd_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_sprm_e" sboTerm="SBO:0000627" id="R_EX_sprm_e" name="EX_sperminex" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Spermine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_sprm_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Spermine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_sprm_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_5mthf_e" sboTerm="SBO:0000627" id="R_EX_5mthf_e" name="EX_5methylTHFx" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;5-Methyltetrahydrofolate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_5mthf_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/5-Methyltetrahydrofolate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_5mthf_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_thbpt_e" sboTerm="SBO:0000627" id="R_EX_thbpt_e" name="EX_tetrahydrobiopterinx" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;5,6,7,8-Tetrahydrobiopterin exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_thbpt_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/5,6,7,8-Tetrahydrobiopterin exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_thbpt_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_CE2705_e" sboTerm="SBO:0000627" id="R_EX_CE2705_e" name="EX_dihydrobiopterinx" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Quinonoid Dihydrobiopterin exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_CE2705_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Quinonoid Dihydrobiopterin exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_CE2705_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_crtn_e" sboTerm="SBO:0000627" id="R_EX_crtn_e" name="EX_creatininex" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Creatinine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_crtn_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Creatinine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_crtn_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_his__L_e" sboTerm="SBO:0000627" id="R_EX_his__L_e" name="EX_histidinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-histidine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_his__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-histidine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_his__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_lys__L_e" sboTerm="SBO:0000627" id="R_EX_lys__L_e" name="EX_lysinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-lysine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_lys__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-lysine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_lys__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_cys__L_e" sboTerm="SBO:0000627" id="R_EX_cys__L_e" name="EX_cysteinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-cysteine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_cys__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-cysteine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_cys__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_so3_e" sboTerm="SBO:0000627" id="R_EX_so3_e" name="EX_sulfitex" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Sulfite exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_so3_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Sulfite exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_so3_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_thr__L_e" sboTerm="SBO:0000627" id="R_EX_thr__L_e" name="EX_threoninex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-threonine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_thr__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-threonine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_thr__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_trp__L_e" sboTerm="SBO:0000627" id="R_EX_trp__L_e" name="EX_tryptophanx" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-tryptophan exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_trp__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-tryptophan exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_trp__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_anth_e" sboTerm="SBO:0000627" id="R_EX_anth_e" name="EX_anthx" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Anthranilate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_anth_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Anthranilate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_anth_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_tyr__L_e" sboTerm="SBO:0000627" id="R_EX_tyr__L_e" name="EX_tyrosinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-tyrosine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_tyr__L_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-tyrosine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_tyr__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_Lcystin_e" sboTerm="SBO:0000627" id="R_EX_Lcystin_e" name="EX_cystinex" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;L-cysteate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_Lcystin_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/L-cysteate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_EX_gthrd_e" sboTerm="SBO:0000627" id="R_EX_gthrd_e" name="EX_GSHx" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Reduced glutathione exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_gthrd_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Reduced glutathione exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gthrd_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_HEX1" sboTerm="SBO:0000176" id="R_HEX1" name="GCK1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HEX1">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glc__D_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_g6p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4195"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23302"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4922"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4923"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4925"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_G6PP" sboTerm="SBO:0000176" id="R_G6PP" name="G6PP" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_G6PP">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_g6p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glc__D_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4056"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24861"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__28906"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PGI" sboTerm="SBO:0000176" id="R_PGI" name="GPI" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PGI">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_g6p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_f6p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4458"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PFK" sboTerm="SBO:0000176" id="R_PFK" name="PFK1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PFK">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_f6p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fdp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8878"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8876"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8877"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FBP" sboTerm="SBO:0000176" id="R_FBP" name="FBP" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FBP">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fdp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_f6p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3607"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3606"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FBA" sboTerm="SBO:0000176" id="R_FBA" name="FBPALDO" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FBA">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fdp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dhap_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_g3p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__418"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__417"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__414"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_TPI" sboTerm="SBO:0000176" id="R_TPI" name="TPI" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TPI">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_dhap_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_g3p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12009"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GAPD" sboTerm="SBO:0000176" id="R_GAPD" name="GAPDH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GAPD">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_g3p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_13dpg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24864"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4141"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PGK" sboTerm="SBO:0000176" id="R_PGK" name="PGK" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PGK">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_13dpg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3pg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8896"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8898"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DPGM" sboTerm="SBO:0000176" id="R_DPGM" name="13BPGM" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DPGM">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_13dpg_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_23dpg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8889"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8888"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1093"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DPGase" sboTerm="SBO:0000176" id="R_DPGase" name="23BPGM" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DPGase">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_23dpg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3pg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8889"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8888"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1093"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PGM" sboTerm="SBO:0000176" id="R_PGM" name="PGM_1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PGM">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3pg_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2pg_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8889"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8888"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1093"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ENO" sboTerm="SBO:0000176" id="R_ENO" name="ENO" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ENO">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2pg_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pep_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3350"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3354"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3353"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PYK" sboTerm="SBO:0000176" id="R_PYK" name="PK" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;, &apos;Gluconeogenesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PYK">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Gluconeogenesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pep_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9021"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9020"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_LDH_L" sboTerm="SBO:0000176" id="R_LDH_L" name="LDH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lactic acid fermentation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_LDH_L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lactic acid fermentation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_lac__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6541"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6535"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30866"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6544"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__28335"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21481"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_r0407" sboTerm="SBO:0000176" id="R_r0407" name="ALDO1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0407">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_HC00361_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dhap_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_e4p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__418"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__417"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__414"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PRPPS" sboTerm="SBO:0000176" id="R_PRPPS" name="PRPS1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PRPPS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_r5p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_prpp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9465"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9462"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9463"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_G6PDH2r" sboTerm="SBO:0000176" id="R_G6PDH2r" name="G6PD" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_G6PDH2r">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_g6p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_6pgl_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4057"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PGL" sboTerm="SBO:0000176" id="R_PGL" name="PGLS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PGL">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_6pgl_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_6pgc_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4795"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8903"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GND" sboTerm="SBO:0000176" id="R_GND" name="6PGD" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GND">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_6pgc_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ru5p__D_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8891"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_RPI" sboTerm="SBO:0000176" id="R_RPI" name="RPI" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_RPI">
              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_ru5p__D_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
          <speciesReference species="M_r5p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10297"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_TKT2" sboTerm="SBO:0000176" id="R_TKT2" name="TKT1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              </bqbiol:is>
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          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_e4p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_xu5p__D_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_f6p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_g3p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11835"/>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11834"/>
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        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_RPE" sboTerm="SBO:0000176" id="R_RPE" name="RPE" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_RPE">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
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              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_ru5p__D_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_xu5p__D_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10293"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__45241"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_TKT1" sboTerm="SBO:0000176" id="R_TKT1" name="TKT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TKT1">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_r5p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_xu5p__D_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_g3p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_s7p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11835"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__25313"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11834"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_TALA" sboTerm="SBO:0000176" id="R_TALA" name="TALDO1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TALA">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_g3p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_s7p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_e4p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_f6p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11559"/>
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      </reaction>
      <reaction metaid="meta_R_r0408" sboTerm="SBO:0000176" id="R_r0408" name="SBPase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0408">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_s7p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_HC00361_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8878"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8876"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8877"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PDHm" sboTerm="SBO:0000176" id="R_PDHm" name="PDH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PDHm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pyruvate metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_accoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21350"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2896"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8808"/>
            <fbc:or>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8806"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8807"/>
            </fbc:or>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PCm" sboTerm="SBO:0000176" id="R_PCm" name="PC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PCm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pyruvate metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hco3_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_oaa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8636"/>
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      </reaction>
      <reaction metaid="meta_R_PEPCK_re" sboTerm="SBO:0000176" id="R_PEPCK_re" name="PEPCK" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PEPCK_re">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gtp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_oaa_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gdp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pep_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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      </reaction>
      <reaction metaid="meta_R_CSm" sboTerm="SBO:0000176" id="R_CSm" name="CS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CSm">
              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_accoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_oaa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_cit_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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      </reaction>
      <reaction metaid="meta_R_ACONTm" sboTerm="SBO:0000176" id="R_ACONTm" name="mACO" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ACONTm">
              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
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          </rdf:RDF>
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        <listOfReactants>
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        <listOfProducts>
          <speciesReference species="M_icit_m" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__118"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__117"/>
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        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_ICDHxm" sboTerm="SBO:0000176" id="R_ICDHxm" name="IDH3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ICDHxm">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_icit_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5386"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5385"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5384"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ICDHym" sboTerm="SBO:0000176" id="R_ICDHym" name="IDH2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ICDHym">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_icit_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5383"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_AKGDm" sboTerm="SBO:0000176" id="R_AKGDm" name="AKGDH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_AKGDm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_succoa_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8124"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2911"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_SUCOAS1m" sboTerm="SBO:0000176" id="R_SUCOAS1m" name="SCS" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SUCOAS1m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_gdp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_succoa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gtp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_succ_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11449"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11450"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_SUCD1m" sboTerm="SBO:0000176" id="R_SUCD1m" name="SDH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SUCD1m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_succ_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fum_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10680"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10681"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10682"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10683"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FUMm" sboTerm="SBO:0000176" id="R_FUMm" name="FH1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FUMm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fum_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_mal__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3700"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MDHm" sboTerm="SBO:0000176" id="R_MDHm" name="MDH2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MDHm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_mal__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_oaa_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6971"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ME1m" sboTerm="SBO:0000176" id="R_ME1m" name="ME2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ME1m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pyruvate metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_mal__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6984"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ME2m" sboTerm="SBO:0000176" id="R_ME2m" name="ME3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ME2m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pyruvate metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_mal__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6985"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ME2" sboTerm="SBO:0000176" id="R_ME2" name="ME1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ME2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pyruvate metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_mal__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6983"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ACITL" sboTerm="SBO:0000176" id="R_ACITL" name="ACLY" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ACITL">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_cit_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_accoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_oaa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__115"/>
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      </reaction>
      <reaction metaid="meta_R_FUM" sboTerm="SBO:0000176" id="R_FUM" name="FH2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Malate and aspartate shuttle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FUM">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Malate and aspartate shuttle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_mal__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3700"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MDH" sboTerm="SBO:0000176" id="R_MDH" name="MDH1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Malate and aspartate shuttle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MDH">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Malate and aspartate shuttle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_mal__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_oaa_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6970"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17836"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_AKGMALtm" sboTerm="SBO:0000176" id="R_AKGMALtm" name="SLC25A11" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_AKGMALtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_mal__L_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
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          <speciesReference species="M_mal__L_c" stoichiometry="1" constant="true"/>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10980"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ACONT" sboTerm="SBO:0000176" id="R_ACONT" name="cACO" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Carbon metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
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                </rdf:Bag>
              </bqbiol:is>
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        <listOfProducts>
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        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ICDHyr" sboTerm="SBO:0000176" id="R_ICDHyr" name="IDH1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Carbon metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ICDHyr">
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                </rdf:Bag>
              </bqbiol:is>
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          </rdf:RDF>
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          <speciesReference species="M_icit_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5382"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PPA" sboTerm="SBO:0000176" id="R_PPA" name="cPPA" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidative phosphorylation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PPA">
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                  <rdf:li rdf:resource="https://identifiers.org/pathways/Oxidative phosphorylation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="2" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30042"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9226"/>
          </fbc:or>
        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_Complex1ROS" sboTerm="SBO:0000176" id="R_Complex1ROS" name="Complex1ROS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidative phosphorylation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_Complex1ROS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Oxidative phosphorylation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_m" stoichiometry="4.75" constant="true"/>
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          <speciesReference species="M_q10_m" stoichiometry="0.95" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="3.8" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_o2s_m" stoichiometry="0.05" constant="true"/>
          <speciesReference species="M_q10h2_m" stoichiometry="0.95" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7694"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7707"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7699"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7697"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7702"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7705"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7715"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7714"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7698"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7692"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7683"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7688"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7684"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7685"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7700"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7693"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7696"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20372"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7704"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7706"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7708"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7701"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7703"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7716"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7712"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7686"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20371"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7717"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7695"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7690"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17194"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7462"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7456"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7461"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7458"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7459"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7455"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7460"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7710"/>
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        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FADH2ETC" sboTerm="SBO:0000176" id="R_FADH2ETC" name="Complex2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidative phosphorylation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FADH2ETC">
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                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Oxidative phosphorylation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_q10_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_fad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_q10h2_m" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidative phosphorylation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CYOR_u10mi">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Oxidative phosphorylation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ficytC_m" stoichiometry="2" constant="true"/>
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        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_focytC_m" stoichiometry="2" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="4" constant="true"/>
          <speciesReference species="M_q10_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12585"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30862"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12586"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12582"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29594"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12587"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12590"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2579"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30863"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7427"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CYOOm2i" sboTerm="SBO:0000176" id="R_CYOOm2i" name="Complex4" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidative phosphorylation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
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        <listOfProducts>
          <speciesReference species="M_ficytC_m" stoichiometry="4" constant="true"/>
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          <speciesReference species="M_h_c" stoichiometry="4" constant="true"/>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2267"/>
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            <fbc:or>
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            <fbc:or>
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            <fbc:or>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16232"/>
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            <fbc:or>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2291"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24381"/>
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            <fbc:or>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2294"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__24382"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidative phosphorylation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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      </reaction>
      <reaction metaid="meta_R_GLUCYS" sboTerm="SBO:0000176" id="R_GLUCYS" name="GCL" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism &apos;]</p>
          </html>
        </notes>
        <annotation>
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              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
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        <listOfProducts>
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        </fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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          <speciesReference species="M_gly_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
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      <reaction metaid="meta_R_SPODMm" sboTerm="SBO:0000176" id="R_SPODMm" name="SOD2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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          <speciesReference species="M_o2_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11180"/>
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      <reaction metaid="meta_R_GTHPi" sboTerm="SBO:0000176" id="R_GTHPi" name="GPcit" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9353"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4554"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4553"/>
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      <reaction metaid="meta_R_GTHPm" sboTerm="SBO:0000176" id="R_GTHPm" name="GPmit" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
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          </rdf:RDF>
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        <listOfProducts>
          <speciesReference species="M_gthox_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="2" constant="true"/>
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        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_GDR" sboTerm="SBO:0000176" id="R_GDR" name="cGSRnadh" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfProducts>
          <speciesReference species="M_gthrd_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4623"/>
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      <reaction metaid="meta_R_GTHOr" sboTerm="SBO:0000176" id="R_GTHOr" name="cGSRnadph" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                <rdf:Bag>
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        <listOfProducts>
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          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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      </reaction>
      <reaction metaid="meta_R_GDRm" sboTerm="SBO:0000176" id="R_GDRm" name="mGSRnadh" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
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        <listOfProducts>
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        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_GTHOm" sboTerm="SBO:0000176" id="R_GTHOm" name="mGSRnadph" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GTHOm">
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              </bqbiol:is>
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          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_gthox_m" stoichiometry="1" constant="true"/>
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        <listOfProducts>
          <speciesReference species="M_gthrd_m" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4623"/>
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      <reaction metaid="meta_R_r0885" sboTerm="SBO:0000176" id="R_r0885" name="TrasportGSH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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          </rdf:RDF>
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        <listOfProducts>
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          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10980"/>
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      <reaction metaid="meta_R_PYRt2m" sboTerm="SBO:0000176" id="R_PYRt2m" name="MPC" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
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          </rdf:RDF>
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        <listOfReactants>
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        <listOfProducts>
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        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21606"/>
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      <reaction metaid="meta_R_HMR_4964" sboTerm="SBO:0000176" id="R_HMR_4964" name="SLC25A1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Alternative Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_cit_m" stoichiometry="1" constant="true"/>
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        <listOfProducts>
          <speciesReference species="M_cit_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_r2420" sboTerm="SBO:0000176" id="R_r2420" name="SLC25A2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pi transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r2420">
              <bqbiol:is>
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              </bqbiol:is>
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          </rdf:RDF>
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        <listOfProducts>
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        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10989"/>
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      </reaction>
      <reaction metaid="meta_R_ATPtm" sboTerm="SBO:0000176" id="R_ATPtm" name="ANT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;ATP transport &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ATPtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/ATP transport "/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10991"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10990"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10992"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FUMtm" sboTerm="SBO:0000176" id="R_FUMtm" name="SLC25A10" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fumarate transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FUMtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Fumarate transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_fum_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10980"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CO2tm" sboTerm="SBO:0000176" id="R_CO2tm" name="TransportCO2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;CO2 transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CO2tm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/CO2 transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_O2tm" sboTerm="SBO:0000176" id="R_O2tm" name="TransportO2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Oxidative phosphorylation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_O2tm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Oxidative phosphorylation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_o2_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_r0801" sboTerm="SBO:0000176" id="R_r0801" name="GNT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;GDP transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0801">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/GDP transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gdp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gtp_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gdp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gtp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10992"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_THD1m" sboTerm="SBO:0000176" id="R_THD1m" name="NNT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;NAD metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_THD1m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/NAD metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7863"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_H2Otm" sboTerm="SBO:0000176" id="R_H2Otm" name="AQP8" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Water transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_H2Otm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Water transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_NH4tm" sboTerm="SBO:0000176" id="R_NH4tm" name="TransportNH3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Ammonia detox&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NH4tm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Ammonia detox"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nh4_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_HCO3E" sboTerm="SBO:0000176" id="R_HCO3E" name="cCA" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Miscellaneous&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HCO3E">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Miscellaneous"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hco3_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1371"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1373"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1383"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1372"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1380"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1368"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1374"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1375"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1381"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14914"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HCO3Em" sboTerm="SBO:0000176" id="R_HCO3Em" name="mCA" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Miscellaneous&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HCO3Em">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Miscellaneous"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hco3_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1378"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1377"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLUN" sboTerm="SBO:0000176" id="R_GLUN" name="cGLS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLUN">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gln__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4331"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLNS" sboTerm="SBO:0000176" id="R_GLNS" name="GS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLNS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gln__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4341"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21016"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLUt2m" sboTerm="SBO:0000176" id="R_GLUt2m" name="GluCarrier" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLUt2m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19954"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10988"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLNtm_1" sboTerm="SBO:0000176" id="R_GLNtm_1" name="GlnCarrier" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
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          <speciesReference species="M_prpp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_orot5p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
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          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12563"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_OMPDC" sboTerm="SBO:0000176" id="R_OMPDC" name="UMPS2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyrimidine synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_OMPDC">
              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
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          <speciesReference species="M_orot5p_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ump_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12563"/>
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      <reaction metaid="meta_R_UMPK" sboTerm="SBO:0000176" id="R_UMPK" name="CMPK1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_UMPK">
              <bqbiol:is>
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                </rdf:Bag>
              </bqbiol:is>
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          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ump_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
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          <speciesReference species="M_udp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18170"/>
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      <reaction metaid="meta_R_RNDR4" sboTerm="SBO:0000176" id="R_RNDR4" name="RRM2B3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_RNDR4">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_udp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dudp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10451"/>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17296"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10452"/>
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          </fbc:and>
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      <reaction metaid="meta_R_TMDS" sboTerm="SBO:0000176" id="R_TMDS" name="TYMS" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TMDS">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_dump_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_mlthf_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dhf_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dtmp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12441"/>
        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_URIDK2r" sboTerm="SBO:0000176" id="R_URIDK2r" name="CMPK2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_URIDK2r">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dudp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dump_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3061"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_NDPK2" sboTerm="SBO:0000176" id="R_NDPK2" name="NME1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NDPK2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Nucleotide synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
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          <speciesReference species="M_udp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
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        <fbc:geneProductAssociation>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/>
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          </fbc:or>
        </fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NDPK3">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Nucleotide synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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          <speciesReference species="M_ctp_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_cdp_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfProducts>
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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          </rdf:RDF>
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        <listOfReactants>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutamate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              </bqbiol:is>
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          </rdf:RDF>
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        <listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutamate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Malate and aspartate shuttle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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      </reaction>
      <reaction metaid="meta_R_ASPTAm" sboTerm="SBO:0000176" id="R_ASPTAm" name="mGOT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Malate and aspartate shuttle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ASPTAm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Malate and aspartate shuttle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_oaa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_asp__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4433"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ASPGLUm" sboTerm="SBO:0000176" id="R_ASPGLUm" name="GLAST" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Malate and aspartate shuttle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ASPGLUm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Malate and aspartate shuttle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asp__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10983"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10982"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ASPT" sboTerm="SBO:0000176" id="R_ASPT" name="FH3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Malate and aspartate shuttle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ASPT">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Malate and aspartate shuttle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3700"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CBPSam" sboTerm="SBO:0000176" id="R_CBPSam" name="CPS1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Malate and aspartate shuttle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CBPSam">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Malate and aspartate shuttle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_m" stoichiometry="2" constant="true"/>
          <speciesReference species="M_hco3_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_m" stoichiometry="2" constant="true"/>
          <speciesReference species="M_cbp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="2" constant="true"/>
          <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2323"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_OCBTm" sboTerm="SBO:0000176" id="R_OCBTm" name="OTC" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Ammonia detox&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_OCBTm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Ammonia detox"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_cbp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_orn_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_citr__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8512"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ORNt4m" sboTerm="SBO:0000176" id="R_ORNt4m" name="ORNT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Ammonia detox&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ORNt4m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Ammonia detox"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_citr__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_orn_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_citr__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_orn_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10985"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__22921"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ARGSS" sboTerm="SBO:0000176" id="R_ARGSS" name="ASS1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ARGSS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_citr__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_argsuc_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__758"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ARGSL" sboTerm="SBO:0000176" id="R_ARGSL" name="ASL" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ARGSL">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_argsuc_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_arg__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__746"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ARGN" sboTerm="SBO:0000176" id="R_ARGN" name="ARG1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ARGN">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_arg__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_orn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_urea_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__663"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ORNDC" sboTerm="SBO:0000176" id="R_ORNDC" name="ODC1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ORNDC">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_orn_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ptrc_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8109"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_SPMS" sboTerm="SBO:0000176" id="R_SPMS" name="SpermidineSynthase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SPMS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ametam_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ptrc_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5mta_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_spmd_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11296"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_SPRMS" sboTerm="SBO:0000176" id="R_SPRMS" name="SpermineSynthase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SPRMS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ametam_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_spmd_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5mta_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_sprm_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11123"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11296"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ADMDC" sboTerm="SBO:0000176" id="R_ADMDC" name="AMD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ADMDC">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_amet_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ametam_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__457"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MTAP" sboTerm="SBO:0000176" id="R_MTAP" name="MTAP" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MTAP">
              <bqbiol:is>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_5mta_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5mdr1p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ade_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7413"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ADPT" sboTerm="SBO:0000176" id="R_ADPT" name="APRT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ADPT">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_ade_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_prpp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__626"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MTRI" sboTerm="SBO:0000176" id="R_MTRI" name="MRI1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MTRI">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_5mdr1p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5mdru1p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_MDRPD" sboTerm="SBO:0000176" id="R_MDRPD" name="MTRUD" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MDRPD">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_5mdru1p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dkmpp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DKMPPD" sboTerm="SBO:0000176" id="R_DKMPPD" name="dkmppDegradation" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DKMPPD">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_dkmpp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2kmb_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_for_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_SPMDtex2" sboTerm="SBO:0000176" id="R_SPMDtex2" name="DMspermidine" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SPMDtex2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_spmd_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_spmd_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_SPRMti" sboTerm="SBO:0000176" id="R_SPRMti" name="DMspermine" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SPRMti">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_sprm_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_sprm_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10963"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLYAMDTRc" sboTerm="SBO:0000176" id="R_GLYAMDTRc" name="AGAT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLYAMDTRc">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_arg__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gly_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gudac_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_orn_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4175"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ARGDr" sboTerm="SBO:0000176" id="R_ARGDr" name="ARGAH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ARGDr">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_arg__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_citr__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_r0074" sboTerm="SBO:0000176" id="R_r0074" name="ALDH18A1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0074">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glu5sa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__406"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLU5SAtmc" sboTerm="SBO:0000176" id="R_GLU5SAtmc" name="TransportGLU5SA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLU5SAtmc">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu5sa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glu5sa_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_G5SADs" sboTerm="SBO:0000176" id="R_G5SADs" name="ALDH4A1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_G5SADs">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu5sa_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_1pyr5c_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__406"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PRO1x" sboTerm="SBO:0000176" id="R_PRO1x" name="P5CR2nadh" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PRO1x">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_1pyr5c_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pro__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30262"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_P5CR" sboTerm="SBO:0000176" id="R_P5CR" name="P5CR2nadph" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_P5CR">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_1pyr5c_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pro__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30262"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PROD2" sboTerm="SBO:0000176" id="R_PROD2" name="PRODH2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PROD2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fad_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pro__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_1pyr5c_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fadh2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17325"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_TransportFAD" sboTerm="SBO:0000176" id="R_TransportFAD" name="TransportFAD" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;FAD transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TransportFAD">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/FAD transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fadh2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_fad_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_ASNS1" sboTerm="SBO:0000176" id="R_ASNS1" name="ASNS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ASNS1">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gln__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_asn__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__753"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ASNN" sboTerm="SBO:0000176" id="R_ASNN" name="ASRGL1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ASNN">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asn__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20123"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_METS" sboTerm="SBO:0000176" id="R_METS" name="MTR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cysteine and methionine cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_METS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cysteine and methionine cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_5mthf_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hcys__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_met__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7468"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_METAT" sboTerm="SBO:0000176" id="R_METAT" name="MAT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cysteine and methionine cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_METAT">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cysteine and methionine cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_met__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_amet_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6903"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6905"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6904"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HMR_3915" sboTerm="SBO:0000176" id="R_HMR_3915" name="HNMT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cysteine and methionine cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HMR_3915">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cysteine and methionine cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_amet_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5mthf_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ahcys_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5028"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_AHCi" sboTerm="SBO:0000176" id="R_AHCi" name="AHCY" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cysteine and methionine cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_AHCi">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cysteine and methionine cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ahcys_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hcys__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ADNK1" sboTerm="SBO:0000176" id="R_ADNK1" name="ADK" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cysteine and methionine cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ADNK1">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cysteine and methionine cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_adn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__257"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CYSTS" sboTerm="SBO:0000176" id="R_CYSTS" name="CBS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CYSTS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_hcys__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_cyst__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1550"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CYSTGL" sboTerm="SBO:0000176" id="R_CYSTGL" name="CTH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CYSTGL">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_cyst__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2obut_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_cys__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2501"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MTHFR3" sboTerm="SBO:0000176" id="R_MTHFR3" name="MTHFR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MTHFR3">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_mlthf_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5mthf_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7436"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_UNK2" sboTerm="SBO:0000176" id="R_UNK2" name="MetSynthesis" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cysteine and methionine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_UNK2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cysteine and methionine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2kmb_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gln__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="2" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_met__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_UNK3" sboTerm="SBO:0000176" id="R_UNK3" name="TAT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cysteine and methionine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_UNK3">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cysteine and methionine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2kmb_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_met__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_5MTHFt" sboTerm="SBO:0000176" id="R_5MTHFt" name="Dm5methylTHF" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_5MTHFt">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_5mthf_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5mthf_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3791"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3795"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ILETA" sboTerm="SBO:0000176" id="R_ILETA" name="cBCAT1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;N-A&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ILETA">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/N-A"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ile__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3mop_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__976"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_3MOPt2im" sboTerm="SBO:0000176" id="R_3MOPt2im" name="Transport3mop" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;N-A&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3MOPt2im">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/N-A"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3mop_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3mop_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_ILETAm" sboTerm="SBO:0000176" id="R_ILETAm" name="mBCAT1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;N-A&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ILETAm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/N-A"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ile__L_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3mop_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__977"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_LEUTA" sboTerm="SBO:0000176" id="R_LEUTA" name="cBCAT2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_LEUTA">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_leu__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_4mop_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__976"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_4MOPt2im" sboTerm="SBO:0000176" id="R_4MOPt2im" name="Transport4mop" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_4MOPt2im">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_4mop_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_4mop_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_LEUTAm" sboTerm="SBO:0000176" id="R_LEUTAm" name="mBCAT2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_LEUTAm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_leu__L_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_4mop_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__977"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_OIVD1m" sboTerm="SBO:0000176" id="R_OIVD1m" name="BCKD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_OIVD1m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_4mop_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ivcoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__987"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2698"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__986"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ACOAD8m" sboTerm="SBO:0000176" id="R_ACOAD8m" name="IVD" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ACOAD8m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ivcoa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3mb2coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6186"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MCCCrm" sboTerm="SBO:0000176" id="R_MCCCrm" name="MCC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MCCCrm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3mb2coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hco3_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3mgcoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6936"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6937"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MGCHrm" sboTerm="SBO:0000176" id="R_MGCHrm" name="MGCoAH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MGCHrm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3mgcoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_hmgcoa_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__890"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HMGCOAtm" sboTerm="SBO:0000176" id="R_HMGCOAtm" name="TransportHMGCoA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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            <rdf:Description rdf:about="#meta_R_HMGCOAtm">
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        <listOfProducts>
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      <reaction metaid="meta_R_VALTA" sboTerm="SBO:0000176" id="R_VALTA" name="cBCAT3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <listOfProducts>
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          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
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      <reaction metaid="meta_R_3MOBt2im" sboTerm="SBO:0000176" id="R_3MOBt2im" name="Transport3mob" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
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          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              </bqbiol:is>
            </rdf:Description>
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        <listOfReactants>
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        <listOfProducts>
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                <rdf:Bag>
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              </bqbiol:is>
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        <listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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          <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                <rdf:Bag>
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              </bqbiol:is>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
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            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
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        </notes>
        <annotation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
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        </notes>
        <annotation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
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        </notes>
        <annotation>
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      </reaction>
      <reaction metaid="meta_R_MMALH" sboTerm="SBO:0000176" id="R_MMALH" name="MMALH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MMALH">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_HC00900_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_mmcoa__S_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_MMEm" sboTerm="SBO:0000176" id="R_MMEm" name="MCM1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MMEm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
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        <listOfReactants>
          <speciesReference species="M_mmcoa__S_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_mmcoa__R_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16732"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MMMm" sboTerm="SBO:0000176" id="R_MMMm" name="MCM2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine leucine and isoleucine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MMMm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine leucine and isoleucine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_mmcoa__R_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_succoa_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7526"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ILEtmi" sboTerm="SBO:0000176" id="R_ILEtmi" name="TransportIle" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;N-A&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ILEtmi">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/N-A"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ile__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ile__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_LEUt5m" sboTerm="SBO:0000176" id="R_LEUt5m" name="TransportLeu" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Leucine mitochondrial transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_LEUt5m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Leucine mitochondrial transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_leu__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_leu__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_VALt5m" sboTerm="SBO:0000176" id="R_VALt5m" name="TransportVal" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Valine mitochondrial transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_VALt5m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Valine mitochondrial transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_val__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_val__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_PGCD" sboTerm="SBO:0000176" id="R_PGCD" name="PHGDH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PGCD">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycolysis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3pg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3php_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8923"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PSERT" sboTerm="SBO:0000176" id="R_PSERT" name="PSAT1" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PSERT">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3php_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pser__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19129"/>
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      </reaction>
      <reaction metaid="meta_R_PSP_L" sboTerm="SBO:0000176" id="R_PSP_L" name="PSPH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PSP_L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pser__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9577"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GHMT2r" sboTerm="SBO:0000176" id="R_GHMT2r" name="cSHMT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GHMT2r">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gly_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_mlthf_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10850"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_SERD_L" sboTerm="SBO:0000176" id="R_SERD_L" name="SDS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SERD_L">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10691"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30404"/>
          </fbc:or>
        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_ALATA_L" sboTerm="SBO:0000176" id="R_ALATA_L" name="GPT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ALATA_L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ala__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18062"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4552"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_r1435" sboTerm="SBO:0000176" id="R_r1435" name="TransportSer" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycine and serine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r1435">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycine and serine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ser__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_GLYtm" sboTerm="SBO:0000176" id="R_GLYtm" name="TransportGly" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycine and serine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLYtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycine and serine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gly_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gly_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_GHMT2rm" sboTerm="SBO:0000176" id="R_GHMT2rm" name="mSHMT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycine and serine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GHMT2rm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycine and serine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ser__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gly_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_mlthf_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10852"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MLTHFtm" sboTerm="SBO:0000176" id="R_MLTHFtm" name="mlthf Transport" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MLTHFtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_mlthf_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_mlthf_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_r0962" sboTerm="SBO:0000176" id="R_r0962" name="Transport_folate" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0962">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_fol_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_fol_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29683"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FORtm" sboTerm="SBO:0000176" id="R_FORtm" name="TransportFormate" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FORtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_for_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_for_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_r0514" sboTerm="SBO:0000176" id="R_r0514" name="DHFRL1_DHFR_5" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0514">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fol_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dhf_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DHFRim" sboTerm="SBO:0000176" id="R_DHFRim" name="DHFRL1_DHFR_6" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DHFRim">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_dhf_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FTHFLmi" sboTerm="SBO:0000176" id="R_FTHFLmi" name="mMTHFD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FTHFLmi">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_for_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_10fthf_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21055"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MTHFCm" sboTerm="SBO:0000176" id="R_MTHFCm" name="mMTHFD2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MTHFCm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_10fthf_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_methf_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7434"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MTHFDm" sboTerm="SBO:0000176" id="R_MTHFDm" name="mMTHFD3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MTHFDm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_methf_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_mlthf_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7434"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FOLR2" sboTerm="SBO:0000176" id="R_FOLR2" name="cDHFR1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FOLR2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fol_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dhf_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DHFR" sboTerm="SBO:0000176" id="R_DHFR" name="cDHFR2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DHFR">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
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          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2861"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FTHFLi" sboTerm="SBO:0000176" id="R_FTHFLi" name="cMTHFD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FTHFLi">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_for_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_10fthf_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7432"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FTHFDH" sboTerm="SBO:0000176" id="R_FTHFDH" name="cMTHFD2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FTHFDH">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
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          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thf_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26777"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3978"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MTHFC" sboTerm="SBO:0000176" id="R_MTHFC" name="cMTHFD3" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MTHFC">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
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          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
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      <reaction metaid="meta_R_MTHFD" sboTerm="SBO:0000176" id="R_MTHFD" name="cMTHFD4" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <listOfProducts>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
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          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_accoa_c" stoichiometry="2" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_aacoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__94"/>
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      <reaction metaid="meta_R_HMGCOAS" sboTerm="SBO:0000176" id="R_HMGCOAS" name="cHMGCS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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          <speciesReference species="M_aacoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_accoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
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          <speciesReference species="M_hmgcoa_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_HMGCOAR" sboTerm="SBO:0000176" id="R_HMGCOAR" name="Hydroxymethylglutaryl CoA reductase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HMGCOAR">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
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          </rdf:RDF>
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          <speciesReference species="M_hmgcoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="2" constant="true"/>
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        <listOfProducts>
          <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_mev__R_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="2" constant="true"/>
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        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5006"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
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          <speciesReference species="M_mev__R_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5pmev_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7530"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PMEVK" sboTerm="SBO:0000176" id="R_PMEVK" name="Phosphomevalonate kinase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5dpmev_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9141"/>
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      </reaction>
      <reaction metaid="meta_R_IPDDI" sboTerm="SBO:0000176" id="R_IPDDI" name="Isopentenyl-diphosphate D-isomerase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
          <speciesReference species="M_ipdp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dmpp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5387"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23487"/>
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        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DPMVD" sboTerm="SBO:0000176" id="R_DPMVD" name="Diphosphomevalonate decarboxylase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
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        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
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          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_DMATT" sboTerm="SBO:0000176" id="R_DMATT" name="Dimethylallyltranstransferase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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                </rdf:Bag>
              </bqbiol:is>
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        <listOfProducts>
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        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_GRTT" sboTerm="SBO:0000176" id="R_GRTT" name="Geranyltranstransferase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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            <rdf:Description rdf:about="#meta_R_GRTT">
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        <listOfProducts>
          <speciesReference species="M_frdp_c" stoichiometry="1" constant="true"/>
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        </listOfProducts>
        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_HMR_1465" sboTerm="SBO:0000176" id="R_HMR_1465" name="Farnesyl-Diphosphate:Farnesyl-Diphosphate Farnesyltransferase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
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        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_HC01118_c" stoichiometry="1" constant="true"/>
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        </listOfProducts>
        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_HMR_1467" sboTerm="SBO:0000176" id="R_HMR_1467" name="Presqualene-Diphosphate Diphosphate-Lyase (Reducing, Squalene-Forming)" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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                <rdf:Bag>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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      <reaction metaid="meta_R_HMR_1478" sboTerm="SBO:0000176" id="R_HMR_1478" name="Sterol 14Alpha-Demethylase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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          <speciesReference species="M_for_c" stoichiometry="1" constant="true"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              </bqbiol:is>
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        <listOfProducts>
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        </fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
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          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
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        </fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
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        <listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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              </bqbiol:is>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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                </rdf:Bag>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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                </rdf:Bag>
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        <listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        </notes>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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          </html>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
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          </html>
        </notes>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <annotation>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <notes>
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            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
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        <listOfProducts>
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      <reaction metaid="meta_R_r0697" sboTerm="SBO:0000176" id="R_r0697" name="r0697" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
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        <listOfProducts>
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      <reaction metaid="meta_R_r0773" sboTerm="SBO:0000176" id="R_r0773" name="r0773" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <listOfProducts>
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          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_FA160ACPH" sboTerm="SBO:0000176" id="R_FA160ACPH" name="FA160ACPH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <listOfProducts>
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        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_palmitateActivation" sboTerm="SBO:0000176" id="R_palmitateActivation" name="palmitateActivation" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              </bqbiol:is>
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        </fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids β-oxidation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids β-oxidation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              </bqbiol:is>
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        <listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids β-oxidation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_carnitineAcylTransferaseII">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
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        <listOfProducts>
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        </listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids β-oxidation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
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          <speciesReference species="M_fad_m" stoichiometry="7" constant="true"/>
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        <listOfProducts>
          <speciesReference species="M_accoa_m" stoichiometry="8" constant="true"/>
          <speciesReference species="M_fadh2_m" stoichiometry="7" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="7" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="7" constant="true"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Biomass reaction&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycolysis&apos;]</p>
          </html>
        </notes>
        <annotation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11041"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11037"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11010"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18067"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__28750"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__15956"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23155"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23091"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11011"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11006"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18301"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11009"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13445"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13444"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11038"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19119"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_O2t" sboTerm="SBO:0000176" id="R_O2t" name="uptakeO2" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;O2 transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_O2t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/O2 transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_o2_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_gln_L_t" sboTerm="SBO:0000176" id="R_gln_L_t" name="uptakeGln" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000017483 or ENSG00000111371 or ENSG00000134294 or ENSG00000139209 or ENSG00000149150 or ENSG00000174358 or ENSG00000188338 or ENSG00000268104 or (ENSG00000147003 and ENSG00000164363)</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_gln_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gln__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gln__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11058"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_r0963" sboTerm="SBO:0000176" id="R_r0963" name="ExFolate" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0963">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Folate cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fol_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_fol_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3791"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3795"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3793"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_THBPTt" sboTerm="SBO:0000176" id="R_THBPTt" name="ExTetrahydrobiopterinc" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;5,6,7,8-Tetrahydrobiopterin transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_THBPTt">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/5,6,7,8-Tetrahydrobiopterin transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_thbpt_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_thbpt_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_arg_L_t" sboTerm="SBO:0000176" id="R_arg_L_t" name="ExArg" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000003989 or ENSG00000139209 or ENSG00000139514 or ENSG00000165349 or ENSG00000268104</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_arg_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_arg__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_arg__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11065"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_phe_L_t" sboTerm="SBO:0000176" id="R_phe_L_t" name="ExPhe" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000112394 or ENSG00000149150 or ENSG00000167703</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_phe_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_phe__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_phe__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:or>
                <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
                <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
              </fbc:or>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17027"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11066"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ile_L_t" sboTerm="SBO:0000176" id="R_ile_L_t" name="ExIle" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000149150 or ENSG00000167703</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ile_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ile__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ile__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_leu_L_t" sboTerm="SBO:0000176" id="R_leu_L_t" name="ExLeu" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000149150 or ENSG00000167703</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_leu_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_leu__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_leu__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_val_L_t" sboTerm="SBO:0000176" id="R_val_L_t" name="ExVal" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000149150 or ENSG00000167703</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_val_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_val__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_val__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_met_L_t" sboTerm="SBO:0000176" id="R_met_L_t" name="ExMet" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000149150 or ENSG00000167703</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_met_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_met__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_met__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10969"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ser_L_t" sboTerm="SBO:0000176" id="R_ser_L_t" name="ExSer" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000017483 or ENSG00000111371 or ENSG00000123643 or ENSG00000134294 or ENSG00000139209 or ENSG00000149150 or ENSG00000268104 or (ENSG00000130234 and ENSG00000174358) or (ENSG00000147003 and ENSG00000164363) or (ENSG00000147003 and ENSG00000174358)</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ser_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ser__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_gly_t" sboTerm="SBO:0000176" id="R_gly_t" name="ExGly" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000017483 or ENSG00000111371 or ENSG00000123643 or ENSG00000134294 or ENSG00000139209 or ENSG00000165970 or ENSG00000186335 or ENSG00000196517 or ENSG00000268104 or (ENSG00000130234 and ENSG00000174358) or (ENSG00000147003 and ENSG00000164363) or (ENSG00000147003 and ENSG00000174358)</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_gly_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gly_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gly_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11058"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11056"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11056"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11051"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18762"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_asn_L_t" sboTerm="SBO:0000176" id="R_asn_L_t" name="ExAsn" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000017483 or ENSG00000111371 or ENSG00000134294 or ENSG00000139209 or ENSG00000149150 or ENSG00000188338 or ENSG00000268104 or (ENSG00000130234 and ENSG00000174358) or (ENSG00000147003 and ENSG00000164363) or (ENSG00000147003 and ENSG00000174358)</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_asn_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asn__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_asn__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_pro_L_t" sboTerm="SBO:0000176" id="R_pro_L_t" name="ExPro" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000123643 or ENSG00000186335</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_pro_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_pro__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_pro__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11054"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30927"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19660"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18762"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HDCAt" sboTerm="SBO:0000176" id="R_HDCAt" name="ExPalmitate" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HDCAt">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Fatty acids/cholesterol synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_hdca_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_hdca_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4433"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10995"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1663"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10998"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GTHRDt2" sboTerm="SBO:0000176" id="R_GTHRDt2" name="ExGSH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione synthesis &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GTHRDt2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glutathione synthesis "/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gthrd_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gthrd_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_DmLact" sboTerm="SBO:0000176" id="R_DmLact" name="DmLact" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lactate acid fermentation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DmLact">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lactate acid fermentation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_lac__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_lac__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16270"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10928"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10924"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10922"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19119"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_UREAt" sboTerm="SBO:0000176" id="R_UREAt" name="DmUrea" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_UREAt">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_urea_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_urea_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10919"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10918"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DmBiomass" sboTerm="SBO:0000176" id="R_DmBiomass" name="DmBiomass" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Biomass reaction&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DmBiomass">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Biomass reaction"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_BIOMASSA_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_BIOMASSA_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_NH4t" sboTerm="SBO:0000176" id="R_NH4t" name="ExNH3" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Urea cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NH4t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Urea cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nh4_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_PTRCtex2" sboTerm="SBO:0000176" id="R_PTRCtex2" name="DmPutrescine" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine biosynthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PTRCtex2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine biosynthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ptrc_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ptrc_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_GUDACtr2" sboTerm="SBO:0000176" id="R_GUDACtr2" name="ExGA" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Creatine synthase&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GUDACtr2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Creatine synthase"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gudac_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gudac_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_CE2705t" sboTerm="SBO:0000176" id="R_CE2705t" name="ExDihydrobiopterinc" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Biopterin pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CE2705t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Biopterin pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_CE2705_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_CE2705_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11003"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11004"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_Dm2oxobutyrate" sboTerm="SBO:0000176" id="R_Dm2oxobutyrate" name="Dm2oxobutyrate" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;2-oxocarboxylic exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_Dm2oxobutyrate">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/2-oxocarboxylic exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2obut_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2obut_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_H2Ot" sboTerm="SBO:0000176" id="R_H2Ot" name="ExH2O" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Water transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_H2Ot">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Water transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7103"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__638"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__634"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__637"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PHLACHt" sboTerm="SBO:0000176" id="R_PHLACHt" name="ExH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Transport of Phenyl Lactate&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PHLACHt">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Transport of Phenyl Lactate"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_CO2t" sboTerm="SBO:0000176" id="R_CO2t" name="ExCO2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;CO2 transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CO2t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/CO2 transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_DmGSSG" sboTerm="SBO:0000176" id="R_DmGSSG" name="DmGSSG" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glutathione synthesis &apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DmGSSG">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glutathione synthesis "/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gthox_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gthox_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_glu_L_t" sboTerm="SBO:0000176" id="R_glu_L_t" name="DmGlu" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000188338</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_glu_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glu__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10944"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10939"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10941"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10940"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10945"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10971"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ala_L_t" sboTerm="SBO:0000176" id="R_ala_L_t" name="ExAla" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000003989 or ENSG00000017483 or ENSG00000111371 or ENSG00000123643 or ENSG00000134294 or ENSG00000139209 or ENSG00000139514 or ENSG00000165349 or ENSG00000180773 or ENSG00000186335 or ENSG00000188338 or ENSG00000268104 or (ENSG00000130234 and ENSG00000174358) or (ENSG00000147003 and ENSG00000164363) or (ENSG00000147003 and ENSG00000174358)</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ala_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ala__L_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ala__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10942"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19660"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18762"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18761"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_asp_L_t" sboTerm="SBO:0000176" id="R_asp_L_t" name="ExAsp" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000079215 or ENSG00000105143 or ENSG00000106688 or ENSG00000110436 or ENSG00000162383</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_asp_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_asp__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10944"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10939"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10941"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10940"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10945"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18044"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ATPM" sboTerm="SBO:0000176" id="R_ATPM" name="ATPmaintenance" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;ATP maintenance&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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                </rdf:Bag>
              </bqbiol:is>
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          </rdf:RDF>
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        <listOfReactants>
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          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_GACMTRc" sboTerm="SBO:0000176" id="R_GACMTRc" name="GAMT" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Creatine synthase&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GACMTRc">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_amet_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gudac_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ahcys_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_creat_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4136"/>
        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_CKc_cho" sboTerm="SBO:0000176" id="R_CKc_cho" name="CK" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Creatine synthase&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CKc_cho">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_creat_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pcreat_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1994"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1991"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CRTNsyn_cho" sboTerm="SBO:0000176" id="R_CRTNsyn_cho" name="CRTNsynthase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Creatine synthase&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CRTNsyn_cho">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Creatine synthase"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_pcreat_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_crtn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_CRTNtr" sboTerm="SBO:0000176" id="R_CRTNtr" name="DmCreatinine" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Creatine synthase&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CRTNtr">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Creatine synthase"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_crtn_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_crtn_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_NDPK1" sboTerm="SBO:0000176" id="R_NDPK1" name="GTPsynth" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NDPK1">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Nucleotide synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gdp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gtp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_NDPK5" sboTerm="SBO:0000176" id="R_NDPK5" name="dGTPsynth" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NDPK5">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Nucleotide synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dgdp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dgtp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20567"/>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_NDPK8" sboTerm="SBO:0000176" id="R_NDPK8" name="dATPsynth" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NDPK8">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Nucleotide synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dadp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_datp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20461"/>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7849"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_NDPK7" sboTerm="SBO:0000176" id="R_NDPK7" name="dCTPsynth" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NDPK7">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Nucleotide synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dcdp_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dctp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7851"/>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_DTMPK" sboTerm="SBO:0000176" id="R_DTMPK" name="dTDPsynth" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DTMPK">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
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        <listOfReactants>
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        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dtdp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3061"/>
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      </reaction>
      <reaction metaid="meta_R_NDPK4" sboTerm="SBO:0000176" id="R_NDPK4" name="dTTPsynth" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Nucleotide synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_NDPK4">
              <bqbiol:is>
                <rdf:Bag>
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              </bqbiol:is>
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          </rdf:RDF>
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        <listOfReactants>
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        <listOfProducts>
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              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__7850"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000139209</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_his_L_t">
              <bqbiol:is>
                <rdf:Bag>
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                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
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        <listOfReactants>
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        <listOfProducts>
          <speciesReference species="M_his__L_e" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_PTRCOX1" sboTerm="SBO:0000176" id="R_PTRCOX1" name="PTRCOX1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
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        <annotation>
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          <speciesReference species="M_h2o2_c" stoichiometry="1" constant="true"/>
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          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfReactants>
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        <listOfProducts>
          <speciesReference species="M_HC00576_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
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          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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      </reaction>
      <reaction metaid="meta_R_ABUTH" sboTerm="SBO:0000176" id="R_ABUTH" name="ABUTH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ABUTH">
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                <rdf:Bag>
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          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
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        <listOfProducts>
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          <speciesReference species="M_his__L_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__642"/>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__633"/>
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        </fbc:geneProductAssociation>
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      <reaction metaid="meta_R_GLUDC" sboTerm="SBO:0000176" id="R_GLUDC" name="GLUDC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLUDC">
              <bqbiol:is>
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          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4092"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HISDr">
              <bqbiol:is>
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        <listOfReactants>
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        <listOfProducts>
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        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4806"/>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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              <bqbiol:is>
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              </bqbiol:is>
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        <listOfProducts>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_IZPN">
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        <listOfProducts>
          <speciesReference species="M_forglu_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
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      <reaction metaid="meta_R_GluForTx" sboTerm="SBO:0000176" id="R_GluForTx" name="GluForTx" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GluForTx">
              <bqbiol:is>
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              </bqbiol:is>
            </rdf:Description>
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        <listOfReactants>
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        <listOfProducts>
          <speciesReference species="M_5forthf_c" stoichiometry="1" constant="true"/>
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Folate cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;β-Alanine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
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        <listOfReactants>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;β-Alanine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
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        <listOfProducts>
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        <fbc:geneProductAssociation>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;β-Alanine metabolism&apos;]</p>
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        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ASP1DC">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/β-Alanine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ala_B_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4092"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_lys_L_t" sboTerm="SBO:0000176" id="R_lys_L_t" name="ExLys" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000003989 or ENSG00000139209 or ENSG00000139514 or ENSG00000165349</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_lys_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_lys__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_lys__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10969"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11057"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11060"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14679"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11061"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_LYStm" sboTerm="SBO:0000176" id="R_LYStm" name="TransportLys" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lysine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_LYStm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lysine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_lys__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_lys__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10985"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__22921"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_SACCD3m" sboTerm="SBO:0000176" id="R_SACCD3m" name="SACCD3m" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lysine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_SACCD3m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lysine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_lys__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_saccrp__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17366"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_r0525" sboTerm="SBO:0000176" id="R_r0525" name="SACCRPOX" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lysine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0525">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lysine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_saccrp__L_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_L2aadp6sa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17366"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_AASAD3m" sboTerm="SBO:0000176" id="R_AASAD3m" name="AASAD3m" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lysine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_AASAD3m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lysine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_L2aadp6sa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_L2aadp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_r0450" sboTerm="SBO:0000176" id="R_r0450" name="AADPTA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lysine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0450">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lysine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_L2aadp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2oxoadp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17929"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_2OXOADOXm" sboTerm="SBO:0000176" id="R_2OXOADOXm" name="OXOADPOR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Lysine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_2OXOADOXm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Lysine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2oxoadp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glutcoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8124"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21350"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2911"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLUTCOADHm" sboTerm="SBO:0000176" id="R_GLUTCOADHm" name="GLUTCOADHm" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Tryptophan metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLUTCOADHm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Tryptophan metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glutcoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_b2coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4189"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_3HBCDm" sboTerm="SBO:0000176" id="R_3HBCDm" name="ECOAH1m" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Butanoate metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3HBCDm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Butanoate metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_b2coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3hbcoa__R_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23408"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HACD1m" sboTerm="SBO:0000176" id="R_HACD1m" name="HACD1m" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Tryptophan metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HACD1m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Tryptophan metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3hbcoa__R_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_aacoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4799"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4800"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4801"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4803"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HMGCOASm" sboTerm="SBO:0000176" id="R_HMGCOASm" name="mHMGCS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cholesterol metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HMGCOASm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cholesterol metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_aacoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_accoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hmgcoa_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5008"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_cys_L_t" sboTerm="SBO:0000176" id="R_cys_L_t" name="ExCys" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000167703</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_cys_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_cys__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_cys__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__23087"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18070"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CYSO" sboTerm="SBO:0000176" id="R_CYSO" name="CDO1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Taurine and hypotaurine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CYSO">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Taurine and hypotaurine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_cys__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3sala_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="2" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1795"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_3SALATAi" sboTerm="SBO:0000176" id="R_3SALATAi" name="3SALATAc" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3SALATAi">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3sala_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3snpyr_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4432"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_3SALAASPm" sboTerm="SBO:0000176" id="R_3SALAASPm" name="Transport3SALA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3SALAASPm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3sala_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_asp__L_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3sala_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_asp__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10983"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10982"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_3SALATAim" sboTerm="SBO:0000176" id="R_3SALATAim" name="3SALATAm" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3SALATAim">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3sala_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3snpyr_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4433"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_3SPYRSP" sboTerm="SBO:0000176" id="R_3SPYRSP" name="3SPYRSTc" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3SPYRSP">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3snpyr_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_so3_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_3SPYRSPm" sboTerm="SBO:0000176" id="R_3SPYRSPm" name="3SPYRSTm" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3SPYRSPm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3snpyr_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_so3_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_HMR_3951" sboTerm="SBO:0000176" id="R_HMR_3951" name="ExSulfitec" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Sodium-sulfite co-transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HMR_3951">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Sodium-sulfite co-transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_so3_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_so3_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_ExSulfitem" sboTerm="SBO:0000176" id="R_ExSulfitem" name="ExSulfitem" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Sulfite transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ExSulfitem">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Sulfite transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_so3_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_so3_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_PHETHPTOX2" sboTerm="SBO:0000176" id="R_PHETHPTOX2" name="PHETHPTOX2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Phenylanine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PHETHPTOX2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Phenylanine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_phe__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thbpt_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_CE2705_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_tyr__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8582"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_tyr_L_t" sboTerm="SBO:0000176" id="R_tyr_L_t" name="ExTyr" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000112394</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_tyr_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_tyr__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_tyr__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17027"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_TYRTA" sboTerm="SBO:0000176" id="R_TYRTA" name="TYRTA" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TYRTA">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_tyr__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_34hpp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4432"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11573"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_34HPPOR" sboTerm="SBO:0000176" id="R_34HPPOR" name="HPPOR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_34HPPOR">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_34hpp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hgentis_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__5147"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HGNTOR" sboTerm="SBO:0000176" id="R_HGNTOR" name="HGNTOR" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HGNTOR">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_hgentis_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_4mlacac_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4892"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_MACACI" sboTerm="SBO:0000176" id="R_MACACI" name="MACACI" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_MACACI">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_4mlacac_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_4fumacac_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4643"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FUMAC" sboTerm="SBO:0000176" id="R_FUMAC" name="FUMAC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FUMAC">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_4fumacac_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_acac_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fum_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__3579"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_AACOAT" sboTerm="SBO:0000176" id="R_AACOAT" name="AACOAT" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_AACOAT">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_acac_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_aacoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21298"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_thr_L_t" sboTerm="SBO:0000176" id="R_thr_L_t" name="ExThr" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000149150</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_thr_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_thr__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_thr__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13447"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13448"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__9225"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_THRD_L" sboTerm="SBO:0000176" id="R_THRD_L" name="THRD" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_THRD_L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_thr__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2obut_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__10691"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__30404"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_OBDHc" sboTerm="SBO:0000176" id="R_OBDHc" name="OBDH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_OBDHc">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2obut_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppcoa_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_PPCOAtm" sboTerm="SBO:0000176" id="R_PPCOAtm" name="TransportPropCoA" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;PropionilCOA transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PPCOAtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/PropionilCOA transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ppcoa_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ppcoa_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_trp_L_t" sboTerm="SBO:0000176" id="R_trp_L_t" name="ExTrp" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>gpr_old: ENSG00000103257</p>
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_trp_L_t">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_trp__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_trp__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11047"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__27960"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13557"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11063"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11064"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__26441"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__29437"/>
            </fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19660"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__17027"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_TRPO2" sboTerm="SBO:0000176" id="R_TRPO2" name="TRPO2" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TRPO2">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_trp__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_5hoxnfkyn_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6059"/>
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            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11708"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_FKYNH" sboTerm="SBO:0000176" id="R_FKYNH" name="FKYNH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_FKYNH">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_5hoxnfkyn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_Lkynr_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_for_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20910"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_KYN" sboTerm="SBO:0000176" id="R_KYN" name="KYN" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_KYN">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lkynr_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ala__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_anth_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6469"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ANTHte" sboTerm="SBO:0000176" id="R_ANTHte" name="ExAnth" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Tryptophan metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ANTHte">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Tryptophan metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_anth_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_anth_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_KYN3OX" sboTerm="SBO:0000176" id="R_KYN3OX" name="KYN3OX" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_KYN3OX">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lkynr_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hLkynr_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6381"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HKYNH" sboTerm="SBO:0000176" id="R_HKYNH" name="HKYNH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HKYNH">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_hLkynr_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_3hanthrn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ala__L_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__6469"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_3HAO" sboTerm="SBO:0000176" id="R_3HAO" name="3HAO" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_3HAO">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_3hanthrn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_o2_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_cmusa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4796"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PCLAD" sboTerm="SBO:0000176" id="R_PCLAD" name="PCLAD" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PCLAD">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_cmusa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_am6sa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__19288"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_AM6SAD" sboTerm="SBO:0000176" id="R_AM6SAD" name="AM6SADH" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_AM6SAD">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_am6sa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_amuco_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_AMCOXO" sboTerm="SBO:0000176" id="R_AMCOXO" name="AMCOXO" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_AMCOXO">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_amuco_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2oxoadp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_2OXOADPTm" sboTerm="SBO:0000176" id="R_2OXOADPTm" name="Transport2Oxoadp" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacid synthesis/degradation&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_2OXOADPTm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacid synthesis/degradation"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_2oxoadp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_akg_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_2oxoadp_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_akg_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__14411"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CystinePyruvate" sboTerm="SBO:0000176" id="R_CystinePyruvate" name="CystinePyruvate" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CystinePyruvate">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_nh4_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_r0027" sboTerm="SBO:0000176" id="R_r0027" name="CystineReductaseNADPH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r0027">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadph_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_cys__L_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nadp_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__18155"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__12437"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_HMR_3996" sboTerm="SBO:0000176" id="R_HMR_3996" name="CystineReductaseNADH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_HMR_3996">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_cys__L_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_CYSGLTH" sboTerm="SBO:0000176" id="R_CYSGLTH" name="CystineGSH" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Methionine and cysteine metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CYSGLTH">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Methionine and cysteine metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gthrd_c" stoichiometry="2" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_cys__L_c" stoichiometry="2" constant="true"/>
          <speciesReference species="M_gthox_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_ACACT1m" sboTerm="SBO:0000176" id="R_ACACT1m" name="mACAT_backward" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cholesterol metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ACACT1m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cholesterol metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_aacoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_accoa_m" stoichiometry="2" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__93"/>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4801"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4803"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_G3PD1ir" sboTerm="SBO:0000176" id="R_G3PD1ir" name="G3PD1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Glycerophospholipid metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_G3PD1ir">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Glycerophospholipid metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_dhap_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nadh_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glyc3p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_nad_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4455"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GLYC3Ptm" sboTerm="SBO:0000176" id="R_GLYC3Ptm" name="Transport_glycerol3P" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLYC3Ptm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_glyc3p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_glyc3p_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_G3PDm" sboTerm="SBO:0000176" id="R_G3PDm" name="GLY3PFAD" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_G3PDm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_fad_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glyc3p_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dhap_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_fadh2_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_DHAPtm" sboTerm="SBO:0000176" id="R_DHAPtm" name="Transport_DHAP" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pentose phosphate pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_DHAPtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pentose phosphate pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_dhap_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_dhap_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_Transport_ala_B_c_e" id="R_Transport_ala_B_c_e" name="Transport_ala_B_c_e" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;β-Alanine transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_Transport_ala_B_c_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/β-Alanine transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ala_B_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ala_B_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_EX_ala_B_e" id="R_EX_ala_B_e" name="bAlae ExchangeRxn" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;β-Alanine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_ala_B_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/β-Alanine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ala_B_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_TMDK1" id="R_TMDK1" name="TMDK1" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;N-A&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_TMDK1">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/N-A"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_thymd_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_dtmp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11831"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11830"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_THYMDt1" id="R_THYMDt1" name="Thymd Transport" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Thymid transport&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_THYMDt1">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Thymid transport"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_thymd_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_thymd_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11003"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11004"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_EX_thymd_e" id="R_EX_thymd_e" name="thymd ExchangeRxn" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_0_bound">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Thymidine exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_thymd_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Thymidine exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_thymd_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_Transport_HC00576_c_e" id="R_Transport_HC00576_c_e" name="HC00576 Transport" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_Transport_HC00576_c_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_HC00576_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_HC00576_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_EX_HC00576_e" id="R_EX_HC00576_e" name="HC00576 ExchangeRxn" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Exchange reaction&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_HC00576_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Exchange reaction"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_HC00576_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_Transport_4abut_c_e" id="R_Transport_4abut_c_e" name="4abut Transport" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Arginine and proline metabolism&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_Transport_4abut_c_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Arginine and proline metabolism"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_4abut_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_4abut_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_EX_4abut_e" id="R_EX_4abut_e" name="4abut ExchangeRxn" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;4-Aminobutanoate exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_4abut_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/4-Aminobutanoate exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_4abut_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_GLUVESSEC" id="R_GLUVESSEC" name="transporto of GLUVESSEC" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GLUVESSEC">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_e" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16703"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__20151"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__16704"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_EX_chsterol_e" id="R_EX_chsterol_e" name="Exchange of Cholesterol" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Cholesterol exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_chsterol_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Cholesterol exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_chsterol_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_r1050" id="R_r1050" name="Vesicular Transport" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_r1050">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Fatty acids/cholesterol synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_chsterol_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_chsterol_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_EX_gal_e" id="R_EX_gal_e" name="Exchange of D-Galactose" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;D-Galactose exchange&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_EX_gal_e">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/D-Galactose exchange"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gal_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
      </reaction>
      <reaction metaid="meta_R_GALt1r" id="R_GALt1r" name="Galactose Transport (Uniport)" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Galactose pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GALt1r">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Galactose pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gal_e" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_gal_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13812"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11005"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11007"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11006"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__13444"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_GALK" id="R_GALK" name="Galactokinase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Galactose pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_GALK">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Galactose pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gal_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_adp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_gal1p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4118"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4119"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_UGLT" id="R_UGLT" name="UDPglucose-Hexose-1-Phosphate Uridylyltransferase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Galactose pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_UGLT">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Galactose pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_gal1p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_udpg_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_g1p_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_udpgal_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4135"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_PGMT" id="R_PGMT" name="Phosphoglucomutase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Galactose pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PGMT">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Galactose pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_g1p_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_g6p_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8905"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8906"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_UDPG4E" id="R_UDPG4E" name="UDPglucose 4-Epimerase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Galactose pathway&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_UDPG4E">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Galactose pathway"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_udpg_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_udpgal_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__4116"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_t_Lcystin_ala__L" id="R_t_Lcystin_ala__L" name="t_Lcystin_ala__L" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_t_Lcystin_ala__L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_e" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ala__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ala__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11025"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_t_Lcystin_glu__L" id="R_t_Lcystin_glu__L" name="t_Lcystin_glu__L" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_t_Lcystin_glu__L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_e" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_glu__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11059"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11026"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_t_Lcystin_leu__L" id="R_t_Lcystin_leu__L" name="t_Lcystin_leu__L" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_t_Lcystin_leu__L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_e" stoichiometry="1" constant="true"/>
          <speciesReference species="M_leu__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_leu__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11025"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_t_Lcystin_ser__L" id="R_t_Lcystin_ser__L" name="t_Lcystin_ser__L" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Aminoacids uptake/secretion&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_t_Lcystin_ser__L">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Aminoacids uptake/secretion"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_Lcystin_e" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ser__L_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_Lcystin_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ser__L_e" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:and>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11025"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__11067"/>
          </fbc:and>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CSNATr" id="R_CSNATr" name="Carnitine O-Acetyltransferase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CSNATr">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Fatty acids/cholesterol synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_accoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_crn_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_acrn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2342"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CRNCARtm" id="R_CRNCARtm" name="Fatty acid oxidation" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CRNCARtm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Fatty acids/cholesterol synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_acrn_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_crn_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_acrn_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_crn_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__1421"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_CSNATm" id="R_CSNATm" name="Citrate Lyase" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_CSNATm">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Fatty acids/cholesterol synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_acrn_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_accoa_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_crn_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2342"/>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ACS" sboTerm="SBO:0000176" id="R_ACS" name="Acetyl-CoA synthetase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>original_bigg_ids: [&apos;ACS&apos;]</p>
            <p>pathways: [&apos;Fatty acids/cholesterol synthesis&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ACS">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/bigg.reaction/ACS"/>
                  <rdf:li rdf:resource="https://identifiers.org/biocyc/META:ACETATE--COA-LIGASE-RXN"/>
                  <rdf:li rdf:resource="https://identifiers.org/ec-code/6.2.1.1"/>
                  <rdf:li rdf:resource="https://identifiers.org/kegg.reaction/R00235"/>
                  <rdf:li rdf:resource="https://identifiers.org/metanetx.reaction/MNXR95413"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-DME-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-TGU-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-BTA-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-CEL-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-DRE-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-CFA-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-TGU-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-SCE-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-CFA-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-BTA-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-SPO-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-CFA-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-MMU-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-GGA-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-OSA-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-HSA-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-HSA-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-SSC-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-RNO-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-SSC-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-BTA-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-GGA-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-SSC-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-XTR-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-ATH-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-DRE-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-DME-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-DDI-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-XTR-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-PFA-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-SCE-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-SCE-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-DRE-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-MMU-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-MMU-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-XTR-71735"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-RNO-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-DDI-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-TGU-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-HSA-8875071"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-GGA-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/reactome.reaction/R-RNO-449911"/>
                  <rdf:li rdf:resource="https://identifiers.org/rhea/23179"/>
                  <rdf:li rdf:resource="https://identifiers.org/rhea/23178"/>
                  <rdf:li rdf:resource="https://identifiers.org/rhea/23176"/>
                  <rdf:li rdf:resource="https://identifiers.org/rhea/23177"/>
                  <rdf:li rdf:resource="https://identifiers.org/sabiork/179"/>
                  <rdf:li rdf:resource="https://identifiers.org/seed.reaction/rxn00175"/>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Fatty acids/cholesterol synthesis"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ac_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_atp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_coa_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_accoa_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_amp_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_ppi_c" stoichiometry="1" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__15814"/>
            <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21298"/>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
      <reaction metaid="meta_R_ACt2m" id="R_ACt2m" name="Acetate mitochondrial transport via proton symport" reversible="true" fast="false" fbc:lowerFluxBound="cobra_default_lb" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Transport reaction&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_ACt2m">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Transport reaction"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_ac_c" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_c" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ac_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_PyrODC" id="R_PyrODC" name="Oxidative decarboxylation of pyruvate facilitated by ROS" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Pyruvate decarboxylase&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_PyrODC">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Pyruvate decarboxylase"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ac_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
        </listOfProducts>
      </reaction>
      <reaction metaid="meta_R_Incompox_Pyr" id="R_Incompox_Pyr" name="Incomplete oxidation of pyruvate by ketoacid dehydrogenase" reversible="false" fast="false" fbc:lowerFluxBound="cobra_0_bound" fbc:upperFluxBound="cobra_default_ub">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>pathways: [&apos;Krebs cycle&apos;]</p>
          </html>
        </notes>
        <annotation>
          <rdf:RDF xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#" xmlns:dcterms="http://purl.org/dc/terms/" xmlns:vCard="http://www.w3.org/2001/vcard-rdf/3.0#" xmlns:vCard4="http://www.w3.org/2006/vcard/ns#" xmlns:bqbiol="http://biomodels.net/biology-qualifiers/" xmlns:bqmodel="http://biomodels.net/model-qualifiers/">
            <rdf:Description rdf:about="#meta_R_Incompox_Pyr">
              <bqbiol:is>
                <rdf:Bag>
                  <rdf:li rdf:resource="https://identifiers.org/pathways/Krebs cycle"/>
                </rdf:Bag>
              </bqbiol:is>
            </rdf:Description>
          </rdf:RDF>
        </annotation>
        <listOfReactants>
          <speciesReference species="M_h2o_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_pyr_m" stoichiometry="1" constant="true"/>
        </listOfReactants>
        <listOfProducts>
          <speciesReference species="M_ac_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_co2_m" stoichiometry="1" constant="true"/>
          <speciesReference species="M_h_m" stoichiometry="2" constant="true"/>
        </listOfProducts>
        <fbc:geneProductAssociation>
          <fbc:or>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__21350"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2896"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8808"/>
              <fbc:or>
                <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8806"/>
                <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8807"/>
              </fbc:or>
            </fbc:and>
            <fbc:and>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2898"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__8124"/>
              <fbc:geneProductRef fbc:geneProduct="G_HGNC__58__2911"/>
            </fbc:and>
          </fbc:or>
        </fbc:geneProductAssociation>
      </reaction>
    </listOfReactions>
    <fbc:listOfObjectives fbc:activeObjective="obj">
      <fbc:objective fbc:id="obj" fbc:type="maximize">
        <fbc:listOfFluxObjectives>
          <fbc:fluxObjective fbc:reaction="R_Biomass" fbc:coefficient="1"/>
        </fbc:listOfFluxObjectives>
      </fbc:objective>
    </fbc:listOfObjectives>
    <fbc:listOfGeneProducts>
      <fbc:geneProduct fbc:id="G_HGNC__58__11830" fbc:name="G_HGNC:11830" fbc:label="G_HGNC__58__11830">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167900</p>
            <p>HGNC ID: HGNC:11830</p>
            <p>HGNC symbol: TK1</p>
            <p>entrez_id: 7083</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11831" fbc:name="G_HGNC:11831" fbc:label="G_HGNC__58__11831">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000166548</p>
            <p>HGNC ID: HGNC:11831</p>
            <p>HGNC symbol: TK2</p>
            <p>entrez_id: 7084</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4925" fbc:name="G_HGNC:4925" fbc:label="G_HGNC__58__4925">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000160883</p>
            <p>HGNC ID: HGNC:4925</p>
            <p>HGNC symbol: HK3</p>
            <p>entrez_id: 3101</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4195" fbc:name="G_HGNC:4195" fbc:label="G_HGNC__58__4195">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000106633</p>
            <p>HGNC ID: HGNC:4195</p>
            <p>HGNC symbol: GCK</p>
            <p>entrez_id: 2645</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4922" fbc:name="G_HGNC:4922" fbc:label="G_HGNC__58__4922">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000156515</p>
            <p>HGNC ID: HGNC:4922</p>
            <p>HGNC symbol: HK1</p>
            <p>entrez_id: 3098</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4923" fbc:name="G_HGNC:4923" fbc:label="G_HGNC__58__4923">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000159399</p>
            <p>HGNC ID: HGNC:4923</p>
            <p>HGNC symbol: HK2</p>
            <p>entrez_id: 3099</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__23302" fbc:name="G_HGNC:23302" fbc:label="G_HGNC__58__23302">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000156510</p>
            <p>HGNC ID: HGNC:23302</p>
            <p>HGNC symbol: HKDC1</p>
            <p>entrez_id: 80201</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4056" fbc:name="G_HGNC:4056" fbc:label="G_HGNC__58__4056">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131482</p>
            <p>HGNC ID: HGNC:4056</p>
            <p>HGNC symbol: G6PC1</p>
            <p>entrez_id: 2538</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__28906" fbc:name="G_HGNC:28906" fbc:label="G_HGNC__58__28906">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000152254</p>
            <p>HGNC ID: HGNC:28906</p>
            <p>HGNC symbol: G6PC2</p>
            <p>entrez_id: 57818</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__24861" fbc:name="G_HGNC:24861" fbc:label="G_HGNC__58__24861">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000141349</p>
            <p>HGNC ID: HGNC:24861</p>
            <p>HGNC symbol: G6PC3</p>
            <p>entrez_id: 92579</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4458" fbc:name="G_HGNC:4458" fbc:label="G_HGNC__58__4458">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000105220</p>
            <p>HGNC ID: HGNC:4458</p>
            <p>HGNC symbol: GPI</p>
            <p>entrez_id: 2821</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__8877" fbc:name="G_HGNC:8877" fbc:label="G_HGNC__58__8877">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000152556</p>
            <p>HGNC ID: HGNC:8877</p>
            <p>HGNC symbol: PFKM</p>
            <p>entrez_id: 5213</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__8876" fbc:name="G_HGNC:8876" fbc:label="G_HGNC__58__8876">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000141959</p>
            <p>HGNC ID: HGNC:8876</p>
            <p>HGNC symbol: PFKL</p>
            <p>entrez_id: 5211</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__8878" fbc:name="G_HGNC:8878" fbc:label="G_HGNC__58__8878">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000067057</p>
            <p>HGNC ID: HGNC:8878</p>
            <p>HGNC symbol: PFKP</p>
            <p>entrez_id: 5214</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__3606" fbc:name="G_HGNC:3606" fbc:label="G_HGNC__58__3606">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000165140</p>
            <p>HGNC ID: HGNC:3606</p>
            <p>HGNC symbol: FBP1</p>
            <p>entrez_id: 2203</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__3607" fbc:name="G_HGNC:3607" fbc:label="G_HGNC__58__3607">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000130957</p>
            <p>HGNC ID: HGNC:3607</p>
            <p>HGNC symbol: FBP2</p>
            <p>entrez_id: 8789</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__417" fbc:name="G_HGNC:417" fbc:label="G_HGNC__58__417">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000136872</p>
            <p>HGNC ID: HGNC:417</p>
            <p>HGNC symbol: ALDOB</p>
            <p>entrez_id: 229</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__418" fbc:name="G_HGNC:418" fbc:label="G_HGNC__58__418">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000109107</p>
            <p>HGNC ID: HGNC:418</p>
            <p>HGNC symbol: ALDOC</p>
            <p>entrez_id: 230</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__414" fbc:name="G_HGNC:414" fbc:label="G_HGNC__58__414">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000149925</p>
            <p>HGNC ID: HGNC:414</p>
            <p>HGNC symbol: ALDOA</p>
            <p>entrez_id: 226</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__12009" fbc:name="G_HGNC:12009" fbc:label="G_HGNC__58__12009">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000111669</p>
            <p>HGNC ID: HGNC:12009</p>
            <p>HGNC symbol: TPI1</p>
            <p>entrez_id: 7167</p>
          </html>
        </notes>
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            <p>ENSG: ENSG00000105679</p>
            <p>HGNC ID: HGNC:24864</p>
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            <p>ENSG: ENSG00000111640</p>
            <p>HGNC ID: HGNC:4141</p>
            <p>HGNC symbol: GAPDH</p>
            <p>entrez_id: 2597</p>
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            <p>ENSG: ENSG00000102144</p>
            <p>HGNC ID: HGNC:8896</p>
            <p>HGNC symbol: PGK1</p>
            <p>entrez_id: 5230</p>
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            <p>ENSG: ENSG00000170950</p>
            <p>HGNC ID: HGNC:8898</p>
            <p>HGNC symbol: PGK2</p>
            <p>entrez_id: 5232</p>
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            <p>ENSG: ENSG00000164708</p>
            <p>HGNC ID: HGNC:8889</p>
            <p>HGNC symbol: PGAM2</p>
            <p>entrez_id: 5224</p>
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            <p>ENSG: ENSG00000172331</p>
            <p>HGNC ID: HGNC:1093</p>
            <p>HGNC symbol: BPGM</p>
            <p>entrez_id: 669</p>
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        <notes>
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            <p>ENSG: ENSG00000171314</p>
            <p>HGNC ID: HGNC:8888</p>
            <p>HGNC symbol: PGAM1</p>
            <p>entrez_id: 5223</p>
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        <notes>
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            <p>ENSG: ENSG00000111674</p>
            <p>HGNC ID: HGNC:3353</p>
            <p>HGNC symbol: ENO2</p>
            <p>entrez_id: 2026</p>
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        <notes>
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            <p>ENSG: ENSG00000074800</p>
            <p>HGNC ID: HGNC:3350</p>
            <p>HGNC symbol: ENO1</p>
            <p>entrez_id: 2023</p>
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        <notes>
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            <p>ENSG: ENSG00000108515</p>
            <p>HGNC ID: HGNC:3354</p>
            <p>HGNC symbol: ENO3</p>
            <p>entrez_id: 2027</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__9021" fbc:name="G_HGNC:9021" fbc:label="G_HGNC__58__9021">
        <notes>
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            <p>ENSG: ENSG00000067225</p>
            <p>HGNC ID: HGNC:9021</p>
            <p>HGNC symbol: PKM</p>
            <p>entrez_id: 5315</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__9020" fbc:name="G_HGNC:9020" fbc:label="G_HGNC__58__9020">
        <notes>
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            <p>ENSG: ENSG00000143627</p>
            <p>HGNC ID: HGNC:9020</p>
            <p>HGNC symbol: PKLR</p>
            <p>entrez_id: 5313</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__30866" fbc:name="G_HGNC:30866" fbc:label="G_HGNC__58__30866">
        <notes>
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            <p>ENSG: ENSG00000151116</p>
            <p>HGNC ID: HGNC:30866</p>
            <p>HGNC symbol: UEVLD</p>
            <p>entrez_id: 55293</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__28335" fbc:name="G_HGNC:28335" fbc:label="G_HGNC__58__28335">
        <notes>
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            <p>ENSG: ENSG00000166800</p>
            <p>HGNC ID: HGNC:28335</p>
            <p>HGNC symbol: LDHAL6A</p>
            <p>entrez_id: 160287</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__21481" fbc:name="G_HGNC:21481" fbc:label="G_HGNC__58__21481">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000171989</p>
            <p>HGNC ID: HGNC:21481</p>
            <p>HGNC symbol: LDHAL6B</p>
            <p>entrez_id: 92483</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__6535" fbc:name="G_HGNC:6535" fbc:label="G_HGNC__58__6535">
        <notes>
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            <p>ENSG: ENSG00000134333</p>
            <p>HGNC ID: HGNC:6535</p>
            <p>HGNC symbol: LDHA</p>
            <p>entrez_id: 3939</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__6544" fbc:name="G_HGNC:6544" fbc:label="G_HGNC__58__6544">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000166796</p>
            <p>HGNC ID: HGNC:6544</p>
            <p>HGNC symbol: LDHC</p>
            <p>entrez_id: 3948</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6541" fbc:name="G_HGNC:6541" fbc:label="G_HGNC__58__6541">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000111716</p>
            <p>HGNC ID: HGNC:6541</p>
            <p>HGNC symbol: LDHB</p>
            <p>entrez_id: 3945</p>
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      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__9465" fbc:name="G_HGNC:9465" fbc:label="G_HGNC__58__9465">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000101911</p>
            <p>HGNC ID: HGNC:9465</p>
            <p>HGNC symbol: PRPS2</p>
            <p>entrez_id: 5634</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__9463" fbc:name="G_HGNC:9463" fbc:label="G_HGNC__58__9463">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000229937</p>
            <p>HGNC ID: HGNC:9463</p>
            <p>HGNC symbol: PRPS1L1</p>
            <p>entrez_id: 221823</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__9462" fbc:name="G_HGNC:9462" fbc:label="G_HGNC__58__9462">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000147224</p>
            <p>HGNC ID: HGNC:9462</p>
            <p>HGNC symbol: PRPS1</p>
            <p>entrez_id: 5631</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4057" fbc:name="G_HGNC:4057" fbc:label="G_HGNC__58__4057">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000160211</p>
            <p>HGNC ID: HGNC:4057</p>
            <p>HGNC symbol: G6PD</p>
            <p>entrez_id: 2539</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4795" fbc:name="G_HGNC:4795" fbc:label="G_HGNC__58__4795">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000049239</p>
            <p>HGNC ID: HGNC:4795</p>
            <p>HGNC symbol: H6PD</p>
            <p>entrez_id: 9563</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__8903" fbc:name="G_HGNC:8903" fbc:label="G_HGNC__58__8903">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000130313</p>
            <p>HGNC ID: HGNC:8903</p>
            <p>HGNC symbol: PGLS</p>
            <p>entrez_id: 25796</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__8891" fbc:name="G_HGNC:8891" fbc:label="G_HGNC__58__8891">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000142657</p>
            <p>HGNC ID: HGNC:8891</p>
            <p>HGNC symbol: PGD</p>
            <p>entrez_id: 5226</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10297" fbc:name="G_HGNC:10297" fbc:label="G_HGNC__58__10297">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000153574</p>
            <p>HGNC ID: HGNC:10297</p>
            <p>HGNC symbol: RPIA</p>
            <p>entrez_id: 22934</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__25313" fbc:name="G_HGNC:25313" fbc:label="G_HGNC__58__25313">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000151005</p>
            <p>HGNC ID: HGNC:25313</p>
            <p>HGNC symbol: TKTL2</p>
            <p>entrez_id: 84076</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000163931</p>
            <p>HGNC ID: HGNC:11834</p>
            <p>HGNC symbol: TKT</p>
            <p>entrez_id: 7086</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000007350</p>
            <p>HGNC ID: HGNC:11835</p>
            <p>HGNC symbol: TKTL1</p>
            <p>entrez_id: 8277</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000197713</p>
            <p>HGNC ID: HGNC:10293</p>
            <p>HGNC symbol: RPE</p>
            <p>entrez_id: 6120</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__45241" fbc:name="G_HGNC:45241" fbc:label="G_HGNC__58__45241">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000235376</p>
            <p>HGNC ID: HGNC:45241</p>
            <p>HGNC symbol: RPEL1</p>
            <p>entrez_id: 729020</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__11559" fbc:name="G_HGNC:11559" fbc:label="G_HGNC__58__11559">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000177156</p>
            <p>HGNC ID: HGNC:11559</p>
            <p>HGNC symbol: TALDO1</p>
            <p>entrez_id: 6888</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000091140</p>
            <p>HGNC ID: HGNC:2898</p>
            <p>HGNC symbol: DLD</p>
            <p>entrez_id: 1738</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000163114</p>
            <p>HGNC ID: HGNC:8807</p>
            <p>HGNC symbol: PDHA2</p>
            <p>entrez_id: 5161</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000168291</p>
            <p>HGNC ID: HGNC:8808</p>
            <p>HGNC symbol: PDHB</p>
            <p>entrez_id: 5162</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000131828</p>
            <p>HGNC ID: HGNC:8806</p>
            <p>HGNC symbol: PDHA1</p>
            <p>entrez_id: 5160</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000150768</p>
            <p>HGNC ID: HGNC:2896</p>
            <p>HGNC symbol: DLAT</p>
            <p>entrez_id: 1737</p>
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        <notes>
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            <p>ENSG: ENSG00000110435</p>
            <p>HGNC ID: HGNC:21350</p>
            <p>HGNC symbol: PDHX</p>
            <p>entrez_id: 8050</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000173599</p>
            <p>HGNC ID: HGNC:8636</p>
            <p>HGNC symbol: PC</p>
            <p>entrez_id: 5091</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000124253</p>
            <p>HGNC ID: HGNC:8724</p>
            <p>HGNC symbol: PCK1</p>
            <p>entrez_id: 5105</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2422" fbc:name="G_HGNC:2422" fbc:label="G_HGNC__58__2422">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000062485</p>
            <p>HGNC ID: HGNC:2422</p>
            <p>HGNC symbol: CS</p>
            <p>entrez_id: 1431</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000122729</p>
            <p>HGNC ID: HGNC:117</p>
            <p>HGNC symbol: ACO1</p>
            <p>entrez_id: 48</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__118" fbc:name="G_HGNC:118" fbc:label="G_HGNC__58__118">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000100412</p>
            <p>HGNC ID: HGNC:118</p>
            <p>HGNC symbol: ACO2</p>
            <p>entrez_id: 50</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000101365</p>
            <p>HGNC ID: HGNC:5385</p>
            <p>HGNC symbol: IDH3B</p>
            <p>entrez_id: 3420</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000166411</p>
            <p>HGNC ID: HGNC:5384</p>
            <p>HGNC symbol: IDH3A</p>
            <p>entrez_id: 3419</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000067829</p>
            <p>HGNC ID: HGNC:5386</p>
            <p>HGNC symbol: IDH3G</p>
            <p>entrez_id: 3421</p>
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        <notes>
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            <p>ENSG: ENSG00000182054</p>
            <p>HGNC ID: HGNC:5383</p>
            <p>HGNC symbol: IDH2</p>
            <p>entrez_id: 3418</p>
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        <notes>
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            <p>ENSG: ENSG00000119689</p>
            <p>HGNC ID: HGNC:2911</p>
            <p>HGNC symbol: DLST</p>
            <p>entrez_id: 1743</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__8124" fbc:name="G_HGNC:8124" fbc:label="G_HGNC__58__8124">
        <notes>
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            <p>ENSG: ENSG00000105953</p>
            <p>HGNC ID: HGNC:8124</p>
            <p>HGNC symbol: OGDH</p>
            <p>entrez_id: 4967</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__11449" fbc:name="G_HGNC:11449" fbc:label="G_HGNC__58__11449">
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            <p>ENSG: ENSG00000163541</p>
            <p>HGNC ID: HGNC:11449</p>
            <p>HGNC symbol: SUCLG1</p>
            <p>entrez_id: 8802</p>
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        <notes>
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            <p>ENSG: ENSG00000172340</p>
            <p>HGNC ID: HGNC:11450</p>
            <p>HGNC symbol: SUCLG2</p>
            <p>entrez_id: 8801</p>
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        <notes>
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            <p>ENSG: ENSG00000073578</p>
            <p>HGNC ID: HGNC:10680</p>
            <p>HGNC symbol: SDHA</p>
            <p>entrez_id: 6389</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10683" fbc:name="G_HGNC:10683" fbc:label="G_HGNC__58__10683">
        <notes>
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            <p>ENSG: ENSG00000204370</p>
            <p>HGNC ID: HGNC:10683</p>
            <p>HGNC symbol: SDHD</p>
            <p>entrez_id: 6392</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10681" fbc:name="G_HGNC:10681" fbc:label="G_HGNC__58__10681">
        <notes>
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            <p>ENSG: ENSG00000117118</p>
            <p>HGNC ID: HGNC:10681</p>
            <p>HGNC symbol: SDHB</p>
            <p>entrez_id: 6390</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10682" fbc:name="G_HGNC:10682" fbc:label="G_HGNC__58__10682">
        <notes>
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            <p>ENSG: ENSG00000143252</p>
            <p>HGNC ID: HGNC:10682</p>
            <p>HGNC symbol: SDHC</p>
            <p>entrez_id: 6391</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__3700" fbc:name="G_HGNC:3700" fbc:label="G_HGNC__58__3700">
        <notes>
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            <p>ENSG: ENSG00000091483</p>
            <p>HGNC ID: HGNC:3700</p>
            <p>HGNC symbol: FH</p>
            <p>entrez_id: 2271</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6971" fbc:name="G_HGNC:6971" fbc:label="G_HGNC__58__6971">
        <notes>
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            <p>ENSG: ENSG00000146701</p>
            <p>HGNC ID: HGNC:6971</p>
            <p>HGNC symbol: MDH2</p>
            <p>entrez_id: 4191</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6984" fbc:name="G_HGNC:6984" fbc:label="G_HGNC__58__6984">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000082212</p>
            <p>HGNC ID: HGNC:6984</p>
            <p>HGNC symbol: ME2</p>
            <p>entrez_id: 4200</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6985" fbc:name="G_HGNC:6985" fbc:label="G_HGNC__58__6985">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000151376</p>
            <p>HGNC ID: HGNC:6985</p>
            <p>HGNC symbol: ME3</p>
            <p>entrez_id: 10873</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6983" fbc:name="G_HGNC:6983" fbc:label="G_HGNC__58__6983">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000065833</p>
            <p>HGNC ID: HGNC:6983</p>
            <p>HGNC symbol: ME1</p>
            <p>entrez_id: 4199</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__115" fbc:name="G_HGNC:115" fbc:label="G_HGNC__58__115">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131473</p>
            <p>HGNC ID: HGNC:115</p>
            <p>HGNC symbol: ACLY</p>
            <p>entrez_id: 47</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6970" fbc:name="G_HGNC:6970" fbc:label="G_HGNC__58__6970">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000014641</p>
            <p>HGNC ID: HGNC:6970</p>
            <p>HGNC symbol: MDH1</p>
            <p>entrez_id: 4190</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__17836" fbc:name="G_HGNC:17836" fbc:label="G_HGNC__58__17836">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000138400</p>
            <p>HGNC ID: HGNC:17836</p>
            <p>HGNC symbol: MDH1B</p>
            <p>entrez_id: 130752</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10980" fbc:name="G_HGNC:10980" fbc:label="G_HGNC__58__10980">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000183048</p>
            <p>HGNC ID: HGNC:10980</p>
            <p>HGNC symbol: SLC25A10</p>
            <p>entrez_id: 1468</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10981" fbc:name="G_HGNC:10981" fbc:label="G_HGNC__58__10981">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000108528</p>
            <p>HGNC ID: HGNC:10981</p>
            <p>HGNC symbol: SLC25A11</p>
            <p>entrez_id: 8402</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__5382" fbc:name="G_HGNC:5382" fbc:label="G_HGNC__58__5382">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000138413</p>
            <p>HGNC ID: HGNC:5382</p>
            <p>HGNC symbol: IDH1</p>
            <p>entrez_id: 3417</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__9226" fbc:name="G_HGNC:9226" fbc:label="G_HGNC__58__9226">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000180817</p>
            <p>HGNC ID: HGNC:9226</p>
            <p>HGNC symbol: PPA1</p>
            <p>entrez_id: 5464</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__30042" fbc:name="G_HGNC:30042" fbc:label="G_HGNC__58__30042">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000107902</p>
            <p>HGNC ID: HGNC:30042</p>
            <p>HGNC symbol: LHPP</p>
            <p>entrez_id: 64077</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7703" fbc:name="G_HGNC:7703" fbc:label="G_HGNC__58__7703">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000166136</p>
            <p>HGNC ID: HGNC:7703</p>
            <p>HGNC symbol: NDUFB8</p>
            <p>entrez_id: 4714</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7690" fbc:name="G_HGNC:7690" fbc:label="G_HGNC__58__7690">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000184983</p>
            <p>HGNC ID: HGNC:7690</p>
            <p>HGNC symbol: NDUFA6</p>
            <p>entrez_id: 4700</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7716" fbc:name="G_HGNC:7716" fbc:label="G_HGNC__58__7716">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167792</p>
            <p>HGNC ID: HGNC:7716</p>
            <p>HGNC symbol: NDUFV1</p>
            <p>entrez_id: 4723</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7717" fbc:name="G_HGNC:7717" fbc:label="G_HGNC__58__7717">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000178127</p>
            <p>HGNC ID: HGNC:7717</p>
            <p>HGNC symbol: NDUFV2</p>
            <p>entrez_id: 4729</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7461" fbc:name="G_HGNC:7461" fbc:label="G_HGNC__58__7461">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198786</p>
            <p>HGNC ID: HGNC:7461</p>
            <p>HGNC symbol: MT-ND5</p>
            <p>entrez_id: 4540</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7696" fbc:name="G_HGNC:7696" fbc:label="G_HGNC__58__7696">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000140990</p>
            <p>HGNC ID: HGNC:7696</p>
            <p>HGNC symbol: NDUFB10</p>
            <p>entrez_id: 4716</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__20371" fbc:name="G_HGNC:20371" fbc:label="G_HGNC__58__20371">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000174886</p>
            <p>HGNC ID: HGNC:20371</p>
            <p>HGNC symbol: NDUFA11</p>
            <p>entrez_id: 126328</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7460" fbc:name="G_HGNC:7460" fbc:label="G_HGNC__58__7460">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000212907</p>
            <p>HGNC ID: HGNC:7460</p>
            <p>HGNC symbol: MT-ND4L</p>
            <p>entrez_id: 4539</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7685" fbc:name="G_HGNC:7685" fbc:label="G_HGNC__58__7685">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131495</p>
            <p>HGNC ID: HGNC:7685</p>
            <p>HGNC symbol: NDUFA2</p>
            <p>entrez_id: 4695</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__7714" fbc:name="G_HGNC:7714" fbc:label="G_HGNC__58__7714">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000115286</p>
            <p>HGNC ID: HGNC:7714</p>
            <p>HGNC symbol: NDUFS7</p>
            <p>entrez_id: 374291</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7686" fbc:name="G_HGNC:7686" fbc:label="G_HGNC__58__7686">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000170906</p>
            <p>HGNC ID: HGNC:7686</p>
            <p>HGNC symbol: NDUFA3</p>
            <p>entrez_id: 4696</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000109390</p>
            <p>HGNC ID: HGNC:7705</p>
            <p>HGNC symbol: NDUFC1</p>
            <p>entrez_id: 4717</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7455" fbc:name="G_HGNC:7455" fbc:label="G_HGNC__58__7455">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198888</p>
            <p>HGNC ID: HGNC:7455</p>
            <p>HGNC symbol: MT-ND1</p>
            <p>entrez_id: 4535</p>
          </html>
        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000213619</p>
            <p>HGNC ID: HGNC:7710</p>
            <p>HGNC symbol: NDUFS3</p>
            <p>entrez_id: 4722</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__17194" fbc:name="G_HGNC:17194" fbc:label="G_HGNC__58__17194">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000186010</p>
            <p>HGNC ID: HGNC:17194</p>
            <p>HGNC symbol: NDUFA13</p>
            <p>entrez_id: 51079</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__7699" fbc:name="G_HGNC:7699" fbc:label="G_HGNC__58__7699">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000065518</p>
            <p>HGNC ID: HGNC:7699</p>
            <p>HGNC symbol: NDUFB4</p>
            <p>entrez_id: 4710</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__7692" fbc:name="G_HGNC:7692" fbc:label="G_HGNC__58__7692">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000119421</p>
            <p>HGNC ID: HGNC:7692</p>
            <p>HGNC symbol: NDUFA8</p>
            <p>entrez_id: 4702</p>
          </html>
        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000130414</p>
            <p>HGNC ID: HGNC:7684</p>
            <p>HGNC symbol: NDUFA10</p>
            <p>entrez_id: 4705</p>
          </html>
        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__7707" fbc:name="G_HGNC:7707" fbc:label="G_HGNC__58__7707">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000023228</p>
            <p>HGNC ID: HGNC:7707</p>
            <p>HGNC symbol: NDUFS1</p>
            <p>entrez_id: 4719</p>
          </html>
        </notes>
      </fbc:geneProduct>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000165264</p>
            <p>HGNC ID: HGNC:7701</p>
            <p>HGNC symbol: NDUFB6</p>
            <p>entrez_id: 4712</p>
          </html>
        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000099795</p>
            <p>HGNC ID: HGNC:7702</p>
            <p>HGNC symbol: NDUFB7</p>
            <p>entrez_id: 4713</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000158864</p>
            <p>HGNC ID: HGNC:7708</p>
            <p>HGNC symbol: NDUFS2</p>
            <p>entrez_id: 4720</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198840</p>
            <p>HGNC ID: HGNC:7458</p>
            <p>HGNC symbol: MT-ND3</p>
            <p>entrez_id: 4537</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000090266</p>
            <p>HGNC ID: HGNC:7697</p>
            <p>HGNC symbol: NDUFB2</p>
            <p>entrez_id: 4708</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198763</p>
            <p>HGNC ID: HGNC:7456</p>
            <p>HGNC symbol: MT-ND2</p>
            <p>entrez_id: 4536</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000125356</p>
            <p>HGNC ID: HGNC:7683</p>
            <p>HGNC symbol: NDUFA1</p>
            <p>entrez_id: 4694</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000168653</p>
            <p>HGNC ID: HGNC:7712</p>
            <p>HGNC symbol: NDUFS5</p>
            <p>entrez_id: 4725</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000136521</p>
            <p>HGNC ID: HGNC:7700</p>
            <p>HGNC symbol: NDUFB5</p>
            <p>entrez_id: 4711</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198695</p>
            <p>HGNC ID: HGNC:7462</p>
            <p>HGNC symbol: MT-ND6</p>
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            <p>ENSG: ENSG00000198886</p>
            <p>HGNC ID: HGNC:7459</p>
            <p>HGNC symbol: MT-ND4</p>
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            <p>ENSG: ENSG00000128609</p>
            <p>HGNC ID: HGNC:7688</p>
            <p>HGNC symbol: NDUFA5</p>
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            <p>ENSG: ENSG00000004779</p>
            <p>HGNC ID: HGNC:7694</p>
            <p>HGNC symbol: NDUFAB1</p>
            <p>entrez_id: 4706</p>
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            <p>ENSG: ENSG00000110717</p>
            <p>HGNC ID: HGNC:7715</p>
            <p>HGNC symbol: NDUFS8</p>
            <p>entrez_id: 4728</p>
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            <p>ENSG: ENSG00000139180</p>
            <p>HGNC ID: HGNC:7693</p>
            <p>HGNC symbol: NDUFA9</p>
            <p>entrez_id: 4704</p>
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            <p>ENSG: ENSG00000147123</p>
            <p>HGNC ID: HGNC:20372</p>
            <p>HGNC symbol: NDUFB11</p>
            <p>entrez_id: 54539</p>
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            <p>ENSG: ENSG00000151366</p>
            <p>HGNC ID: HGNC:7706</p>
            <p>HGNC symbol: NDUFC2</p>
            <p>entrez_id: 4718</p>
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            <p>ENSG: ENSG00000119013</p>
            <p>HGNC ID: HGNC:7698</p>
            <p>HGNC symbol: NDUFB3</p>
            <p>entrez_id: 4709</p>
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        <notes>
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            <p>ENSG: ENSG00000147684</p>
            <p>HGNC ID: HGNC:7704</p>
            <p>HGNC symbol: NDUFB9</p>
            <p>entrez_id: 4715</p>
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        <notes>
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            <p>ENSG: ENSG00000183648</p>
            <p>HGNC ID: HGNC:7695</p>
            <p>HGNC symbol: NDUFB1</p>
            <p>entrez_id: 4707</p>
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        <notes>
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            <p>ENSG: ENSG00000140374</p>
            <p>HGNC ID: HGNC:3481</p>
            <p>HGNC symbol: ETFA</p>
            <p>entrez_id: 2108</p>
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        <notes>
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            <p>ENSG: ENSG00000105379</p>
            <p>HGNC ID: HGNC:3482</p>
            <p>HGNC symbol: ETFB</p>
            <p>entrez_id: 2109</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__3483" fbc:name="G_HGNC:3483" fbc:label="G_HGNC__58__3483">
        <notes>
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            <p>ENSG: ENSG00000171503</p>
            <p>HGNC ID: HGNC:3483</p>
            <p>HGNC symbol: ETFDH</p>
            <p>entrez_id: 2110</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2579" fbc:name="G_HGNC:2579" fbc:label="G_HGNC__58__2579">
        <notes>
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            <p>ENSG: ENSG00000179091</p>
            <p>HGNC ID: HGNC:2579</p>
            <p>HGNC symbol: CYC1</p>
            <p>entrez_id: 1537</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__12590" fbc:name="G_HGNC:12590" fbc:label="G_HGNC__58__12590">
        <notes>
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            <p>ENSG: ENSG00000173660</p>
            <p>HGNC ID: HGNC:12590</p>
            <p>HGNC symbol: UQCRH</p>
            <p>entrez_id: 7388</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__29594" fbc:name="G_HGNC:29594" fbc:label="G_HGNC__58__29594">
        <notes>
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            <p>ENSG: ENSG00000164405</p>
            <p>HGNC ID: HGNC:29594</p>
            <p>HGNC symbol: UQCRQ</p>
            <p>entrez_id: 27089</p>
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        </notes>
      </fbc:geneProduct>
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        <notes>
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            <p>ENSG: ENSG00000169021</p>
            <p>HGNC ID: HGNC:12587</p>
            <p>HGNC symbol: UQCRFS1</p>
            <p>entrez_id: 7386</p>
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        </notes>
      </fbc:geneProduct>
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        <notes>
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            <p>ENSG: ENSG00000156467</p>
            <p>HGNC ID: HGNC:12582</p>
            <p>HGNC symbol: UQCRB</p>
            <p>entrez_id: 7381</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__30863" fbc:name="G_HGNC:30863" fbc:label="G_HGNC__58__30863">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000184076</p>
            <p>HGNC ID: HGNC:30863</p>
            <p>HGNC symbol: UQCR10</p>
            <p>entrez_id: 29796</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7427" fbc:name="G_HGNC:7427" fbc:label="G_HGNC__58__7427">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198727</p>
            <p>HGNC ID: HGNC:7427</p>
            <p>HGNC symbol: MT-CYB</p>
            <p>entrez_id: 4519</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__30862" fbc:name="G_HGNC:30862" fbc:label="G_HGNC__58__30862">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000127540</p>
            <p>HGNC ID: HGNC:30862</p>
            <p>HGNC symbol: UQCR11</p>
            <p>entrez_id: 10975</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000140740</p>
            <p>HGNC ID: HGNC:12586</p>
            <p>HGNC symbol: UQCRC2</p>
            <p>entrez_id: 7385</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__12585" fbc:name="G_HGNC:12585" fbc:label="G_HGNC__58__12585">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000010256</p>
            <p>HGNC ID: HGNC:12585</p>
            <p>HGNC symbol: UQCRC1</p>
            <p>entrez_id: 7384</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2285" fbc:name="G_HGNC:2285" fbc:label="G_HGNC__58__2285">
        <notes>
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            <p>ENSG: ENSG00000164919</p>
            <p>HGNC ID: HGNC:2285</p>
            <p>HGNC symbol: COX6C</p>
            <p>entrez_id: 1345</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2291" fbc:name="G_HGNC:2291" fbc:label="G_HGNC__58__2291">
        <notes>
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            <p>ENSG: ENSG00000131174</p>
            <p>HGNC ID: HGNC:2291</p>
            <p>HGNC symbol: COX7B</p>
            <p>entrez_id: 1349</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__24381" fbc:name="G_HGNC:24381" fbc:label="G_HGNC__58__24381">
        <notes>
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            <p>ENSG: ENSG00000170516</p>
            <p>HGNC ID: HGNC:24381</p>
            <p>HGNC symbol: COX7B2</p>
            <p>entrez_id: 170712</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2267" fbc:name="G_HGNC:2267" fbc:label="G_HGNC__58__2267">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000178741</p>
            <p>HGNC ID: HGNC:2267</p>
            <p>HGNC symbol: COX5A</p>
            <p>entrez_id: 9377</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2287" fbc:name="G_HGNC:2287" fbc:label="G_HGNC__58__2287">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000161281</p>
            <p>HGNC ID: HGNC:2287</p>
            <p>HGNC symbol: COX7A1</p>
            <p>entrez_id: 1346</p>
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        </notes>
      </fbc:geneProduct>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198804</p>
            <p>HGNC ID: HGNC:7419</p>
            <p>HGNC symbol: MT-CO1</p>
            <p>entrez_id: 4512</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000160471</p>
            <p>HGNC ID: HGNC:24380</p>
            <p>HGNC symbol: COX6B2</p>
            <p>entrez_id: 125965</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__7421" fbc:name="G_HGNC:7421" fbc:label="G_HGNC__58__7421">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198712</p>
            <p>HGNC ID: HGNC:7421</p>
            <p>HGNC symbol: MT-CO2</p>
            <p>entrez_id: 4513</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000112695</p>
            <p>HGNC ID: HGNC:2288</p>
            <p>HGNC symbol: COX7A2</p>
            <p>entrez_id: 1347</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__16232" fbc:name="G_HGNC:16232" fbc:label="G_HGNC__58__16232">
        <notes>
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            <p>ENSG: ENSG00000131055</p>
            <p>HGNC ID: HGNC:16232</p>
            <p>HGNC symbol: COX4I2</p>
            <p>entrez_id: 84701</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2294" fbc:name="G_HGNC:2294" fbc:label="G_HGNC__58__2294">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000176340</p>
            <p>HGNC ID: HGNC:2294</p>
            <p>HGNC symbol: COX8A</p>
            <p>entrez_id: 1351</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000111775</p>
            <p>HGNC ID: HGNC:2277</p>
            <p>HGNC symbol: COX6A1</p>
            <p>entrez_id: 1337</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000126267</p>
            <p>HGNC ID: HGNC:2280</p>
            <p>HGNC symbol: COX6B1</p>
            <p>entrez_id: 1340</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__24382" fbc:name="G_HGNC:24382" fbc:label="G_HGNC__58__24382">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000187581</p>
            <p>HGNC ID: HGNC:24382</p>
            <p>HGNC symbol: COX8C</p>
            <p>entrez_id: 341947</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2292" fbc:name="G_HGNC:2292" fbc:label="G_HGNC__58__2292">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000127184</p>
            <p>HGNC ID: HGNC:2292</p>
            <p>HGNC symbol: COX7C</p>
            <p>entrez_id: 1350</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198938</p>
            <p>HGNC ID: HGNC:7422</p>
            <p>HGNC symbol: MT-CO3</p>
            <p>entrez_id: 4514</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000135940</p>
            <p>HGNC ID: HGNC:2269</p>
            <p>HGNC symbol: COX5B</p>
            <p>entrez_id: 1329</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2265" fbc:name="G_HGNC:2265" fbc:label="G_HGNC__58__2265">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131143</p>
            <p>HGNC ID: HGNC:2265</p>
            <p>HGNC symbol: COX4I1</p>
            <p>entrez_id: 1327</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000156885</p>
            <p>HGNC ID: HGNC:2279</p>
            <p>HGNC symbol: COX6A2</p>
            <p>entrez_id: 1339</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000228253</p>
            <p>HGNC ID: HGNC:7415</p>
            <p>HGNC symbol: MT-ATP8</p>
            <p>entrez_id: 4509</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__845" fbc:name="G_HGNC:845" fbc:label="G_HGNC__58__845">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167863</p>
            <p>HGNC ID: HGNC:845</p>
            <p>HGNC symbol: ATP5PD</p>
            <p>entrez_id: 10476</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__833" fbc:name="G_HGNC:833" fbc:label="G_HGNC__58__833">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000165629</p>
            <p>HGNC ID: HGNC:833</p>
            <p>HGNC symbol: ATP5F1C</p>
            <p>entrez_id: 509</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__843" fbc:name="G_HGNC:843" fbc:label="G_HGNC__58__843">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000154518</p>
            <p>HGNC ID: HGNC:843</p>
            <p>HGNC symbol: ATP5MC3</p>
            <p>entrez_id: 518</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__838" fbc:name="G_HGNC:838" fbc:label="G_HGNC__58__838">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000124172</p>
            <p>HGNC ID: HGNC:838</p>
            <p>HGNC symbol: ATP5F1E</p>
            <p>entrez_id: 514</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000154723</p>
            <p>HGNC ID: HGNC:847</p>
            <p>HGNC symbol: ATP5PF</p>
            <p>entrez_id: 522</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__848" fbc:name="G_HGNC:848" fbc:label="G_HGNC__58__848">
        <notes>
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            <p>ENSG: ENSG00000241468</p>
            <p>HGNC ID: HGNC:848</p>
            <p>HGNC symbol: ATP5MF</p>
            <p>entrez_id: 9551</p>
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      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__850" fbc:name="G_HGNC:850" fbc:label="G_HGNC__58__850">
        <notes>
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            <p>ENSG: ENSG00000241837</p>
            <p>HGNC ID: HGNC:850</p>
            <p>HGNC symbol: ATP5PO</p>
            <p>entrez_id: 539</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__840" fbc:name="G_HGNC:840" fbc:label="G_HGNC__58__840">
        <notes>
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            <p>ENSG: ENSG00000116459</p>
            <p>HGNC ID: HGNC:840</p>
            <p>HGNC symbol: ATP5PB</p>
            <p>entrez_id: 515</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__841" fbc:name="G_HGNC:841" fbc:label="G_HGNC__58__841">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000159199</p>
            <p>HGNC ID: HGNC:841</p>
            <p>HGNC symbol: ATP5MC1</p>
            <p>entrez_id: 516</p>
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      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__830" fbc:name="G_HGNC:830" fbc:label="G_HGNC__58__830">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000110955</p>
            <p>HGNC ID: HGNC:830</p>
            <p>HGNC symbol: ATP5F1B</p>
            <p>entrez_id: 506</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__846" fbc:name="G_HGNC:846" fbc:label="G_HGNC__58__846">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000169020</p>
            <p>HGNC ID: HGNC:846</p>
            <p>HGNC symbol: ATP5ME</p>
            <p>entrez_id: 521</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__823" fbc:name="G_HGNC:823" fbc:label="G_HGNC__58__823">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000152234</p>
            <p>HGNC ID: HGNC:823</p>
            <p>HGNC symbol: ATP5F1A</p>
            <p>entrez_id: 498</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__842" fbc:name="G_HGNC:842" fbc:label="G_HGNC__58__842">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000135390</p>
            <p>HGNC ID: HGNC:842</p>
            <p>HGNC symbol: ATP5MC2</p>
            <p>entrez_id: 517</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7414" fbc:name="G_HGNC:7414" fbc:label="G_HGNC__58__7414">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000198899</p>
            <p>HGNC ID: HGNC:7414</p>
            <p>HGNC symbol: MT-ATP6</p>
            <p>entrez_id: 4508</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__14247" fbc:name="G_HGNC:14247" fbc:label="G_HGNC__58__14247">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167283</p>
            <p>HGNC ID: HGNC:14247</p>
            <p>HGNC symbol: ATP5MG</p>
            <p>entrez_id: 10632</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__837" fbc:name="G_HGNC:837" fbc:label="G_HGNC__58__837">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000099624</p>
            <p>HGNC ID: HGNC:837</p>
            <p>HGNC symbol: ATP5F1D</p>
            <p>entrez_id: 513</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4312" fbc:name="G_HGNC:4312" fbc:label="G_HGNC__58__4312">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000023909</p>
            <p>HGNC ID: HGNC:4312</p>
            <p>HGNC symbol: GCLM</p>
            <p>entrez_id: 2730</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4311" fbc:name="G_HGNC:4311" fbc:label="G_HGNC__58__4311">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000001084</p>
            <p>HGNC ID: HGNC:4311</p>
            <p>HGNC symbol: GCLC</p>
            <p>entrez_id: 2729</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4624" fbc:name="G_HGNC:4624" fbc:label="G_HGNC__58__4624">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000100983</p>
            <p>HGNC ID: HGNC:4624</p>
            <p>HGNC symbol: GSS</p>
            <p>entrez_id: 2937</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11180" fbc:name="G_HGNC:11180" fbc:label="G_HGNC__58__11180">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000291237</p>
            <p>HGNC ID: HGNC:11180</p>
            <p>HGNC symbol: SOD2</p>
            <p>entrez_id: 6648</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__9352" fbc:name="G_HGNC:9352" fbc:label="G_HGNC__58__9352">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000117450</p>
            <p>HGNC ID: HGNC:9352</p>
            <p>HGNC symbol: PRDX1</p>
            <p>entrez_id: 5052</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4553" fbc:name="G_HGNC:4553" fbc:label="G_HGNC__58__4553">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000233276</p>
            <p>HGNC ID: HGNC:4553</p>
            <p>HGNC symbol: GPX1</p>
            <p>entrez_id: 2876</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4556" fbc:name="G_HGNC:4556" fbc:label="G_HGNC__58__4556">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167468</p>
            <p>HGNC ID: HGNC:4556</p>
            <p>HGNC symbol: GPX4</p>
            <p>entrez_id: 2879</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__9353" fbc:name="G_HGNC:9353" fbc:label="G_HGNC__58__9353">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167815</p>
            <p>HGNC ID: HGNC:9353</p>
            <p>HGNC symbol: PRDX2</p>
            <p>entrez_id: 7001</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4554" fbc:name="G_HGNC:4554" fbc:label="G_HGNC__58__4554">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000176153</p>
            <p>HGNC ID: HGNC:4554</p>
            <p>HGNC symbol: GPX2</p>
            <p>entrez_id: 2877</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__9354" fbc:name="G_HGNC:9354" fbc:label="G_HGNC__58__9354">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000165672</p>
            <p>HGNC ID: HGNC:9354</p>
            <p>HGNC symbol: PRDX3</p>
            <p>entrez_id: 10935</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4623" fbc:name="G_HGNC:4623" fbc:label="G_HGNC__58__4623">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000104687</p>
            <p>HGNC ID: HGNC:4623</p>
            <p>HGNC symbol: GSR</p>
            <p>entrez_id: 2936</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__21606" fbc:name="G_HGNC:21606" fbc:label="G_HGNC__58__21606">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000060762</p>
            <p>HGNC ID: HGNC:21606</p>
            <p>HGNC symbol: MPC1</p>
            <p>entrez_id: 51660</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__24515" fbc:name="G_HGNC:24515" fbc:label="G_HGNC__58__24515">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000143158</p>
            <p>HGNC ID: HGNC:24515</p>
            <p>HGNC symbol: MPC2</p>
            <p>entrez_id: 25874</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10922" fbc:name="G_HGNC:10922" fbc:label="G_HGNC__58__10922">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000155380</p>
            <p>HGNC ID: HGNC:10922</p>
            <p>HGNC symbol: SLC16A1</p>
            <p>entrez_id: 6566</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10979" fbc:name="G_HGNC:10979" fbc:label="G_HGNC__58__10979">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000100075</p>
            <p>HGNC ID: HGNC:10979</p>
            <p>HGNC symbol: SLC25A1</p>
            <p>entrez_id: 6576</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10989" fbc:name="G_HGNC:10989" fbc:label="G_HGNC__58__10989">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000075415</p>
            <p>HGNC ID: HGNC:10989</p>
            <p>HGNC symbol: SLC25A3</p>
            <p>entrez_id: 5250</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10992" fbc:name="G_HGNC:10992" fbc:label="G_HGNC__58__10992">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000169100</p>
            <p>HGNC ID: HGNC:10992</p>
            <p>HGNC symbol: SLC25A6</p>
            <p>entrez_id: 293</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10991" fbc:name="G_HGNC:10991" fbc:label="G_HGNC__58__10991">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000005022</p>
            <p>HGNC ID: HGNC:10991</p>
            <p>HGNC symbol: SLC25A5</p>
            <p>entrez_id: 292</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10990" fbc:name="G_HGNC:10990" fbc:label="G_HGNC__58__10990">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000151729</p>
            <p>HGNC ID: HGNC:10990</p>
            <p>HGNC symbol: SLC25A4</p>
            <p>entrez_id: 291</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7863" fbc:name="G_HGNC:7863" fbc:label="G_HGNC__58__7863">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000112992</p>
            <p>HGNC ID: HGNC:7863</p>
            <p>HGNC symbol: NNT</p>
            <p>entrez_id: 23530</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__642" fbc:name="G_HGNC:642" fbc:label="G_HGNC__58__642">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000103375</p>
            <p>HGNC ID: HGNC:642</p>
            <p>HGNC symbol: AQP8</p>
            <p>entrez_id: 343</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1371" fbc:name="G_HGNC:1371" fbc:label="G_HGNC__58__1371">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000074410</p>
            <p>HGNC ID: HGNC:1371</p>
            <p>HGNC symbol: CA12</p>
            <p>entrez_id: 771</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1372" fbc:name="G_HGNC:1372" fbc:label="G_HGNC__58__1372">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000118298</p>
            <p>HGNC ID: HGNC:1372</p>
            <p>HGNC symbol: CA14</p>
            <p>entrez_id: 23632</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1368" fbc:name="G_HGNC:1368" fbc:label="G_HGNC__58__1368">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000133742</p>
            <p>HGNC ID: HGNC:1368</p>
            <p>HGNC symbol: CA1</p>
            <p>entrez_id: 759</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__1375" fbc:name="G_HGNC:1375" fbc:label="G_HGNC__58__1375">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167434</p>
            <p>HGNC ID: HGNC:1375</p>
            <p>HGNC symbol: CA4</p>
            <p>entrez_id: 762</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__1380" fbc:name="G_HGNC:1380" fbc:label="G_HGNC__58__1380">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131686</p>
            <p>HGNC ID: HGNC:1380</p>
            <p>HGNC symbol: CA6</p>
            <p>entrez_id: 765</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__1381" fbc:name="G_HGNC:1381" fbc:label="G_HGNC__58__1381">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000168748</p>
            <p>HGNC ID: HGNC:1381</p>
            <p>HGNC symbol: CA7</p>
            <p>entrez_id: 766</p>
          </html>
        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__1374" fbc:name="G_HGNC:1374" fbc:label="G_HGNC__58__1374">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000164879</p>
            <p>HGNC ID: HGNC:1374</p>
            <p>HGNC symbol: CA3</p>
            <p>entrez_id: 761</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__14914" fbc:name="G_HGNC:14914" fbc:label="G_HGNC__58__14914">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000185015</p>
            <p>HGNC ID: HGNC:14914</p>
            <p>HGNC symbol: CA13</p>
            <p>entrez_id: 377677</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1383" fbc:name="G_HGNC:1383" fbc:label="G_HGNC__58__1383">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000107159</p>
            <p>HGNC ID: HGNC:1383</p>
            <p>HGNC symbol: CA9</p>
            <p>entrez_id: 768</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1373" fbc:name="G_HGNC:1373" fbc:label="G_HGNC__58__1373">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000104267</p>
            <p>HGNC ID: HGNC:1373</p>
            <p>HGNC symbol: CA2</p>
            <p>entrez_id: 760</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1377" fbc:name="G_HGNC:1377" fbc:label="G_HGNC__58__1377">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000174990</p>
            <p>HGNC ID: HGNC:1377</p>
            <p>HGNC symbol: CA5A</p>
            <p>entrez_id: 763</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1378" fbc:name="G_HGNC:1378" fbc:label="G_HGNC__58__1378">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000169239</p>
            <p>HGNC ID: HGNC:1378</p>
            <p>HGNC symbol: CA5B</p>
            <p>entrez_id: 11238</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4331" fbc:name="G_HGNC:4331" fbc:label="G_HGNC__58__4331">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000115419</p>
            <p>HGNC ID: HGNC:4331</p>
            <p>HGNC symbol: GLS</p>
            <p>entrez_id: 2744</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4341" fbc:name="G_HGNC:4341" fbc:label="G_HGNC__58__4341">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000135821</p>
            <p>HGNC ID: HGNC:4341</p>
            <p>HGNC symbol: GLUL</p>
            <p>entrez_id: 2752</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__21016" fbc:name="G_HGNC:21016" fbc:label="G_HGNC__58__21016">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000146166</p>
            <p>HGNC ID: HGNC:21016</p>
            <p>HGNC symbol: LGSN</p>
            <p>entrez_id: 51557</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10988" fbc:name="G_HGNC:10988" fbc:label="G_HGNC__58__10988">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000182902</p>
            <p>HGNC ID: HGNC:10988</p>
            <p>HGNC symbol: SLC25A18</p>
            <p>entrez_id: 83733</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__19954" fbc:name="G_HGNC:19954" fbc:label="G_HGNC__58__19954">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000177542</p>
            <p>HGNC ID: HGNC:19954</p>
            <p>HGNC symbol: SLC25A22</p>
            <p>entrez_id: 79751</p>
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            <p>ENSG: ENSG00000135423</p>
            <p>HGNC ID: HGNC:29570</p>
            <p>HGNC symbol: GLS2</p>
            <p>entrez_id: 27165</p>
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            <p>ENSG: ENSG00000128059</p>
            <p>HGNC ID: HGNC:9238</p>
            <p>HGNC symbol: PPAT</p>
            <p>entrez_id: 5471</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4163" fbc:name="G_HGNC:4163" fbc:label="G_HGNC__58__4163">
        <notes>
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            <p>ENSG: ENSG00000159131</p>
            <p>HGNC ID: HGNC:4163</p>
            <p>HGNC symbol: GART</p>
            <p>entrez_id: 2618</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__8863" fbc:name="G_HGNC:8863" fbc:label="G_HGNC__58__8863">
        <notes>
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            <p>ENSG: ENSG00000178921</p>
            <p>HGNC ID: HGNC:8863</p>
            <p>HGNC symbol: PFAS</p>
            <p>entrez_id: 5198</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__8587" fbc:name="G_HGNC:8587" fbc:label="G_HGNC__58__8587">
        <notes>
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            <p>ENSG: ENSG00000128050</p>
            <p>HGNC ID: HGNC:8587</p>
            <p>HGNC symbol: PAICS</p>
            <p>entrez_id: 10606</p>
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      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__291" fbc:name="G_HGNC:291" fbc:label="G_HGNC__58__291">
        <notes>
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            <p>ENSG: ENSG00000239900</p>
            <p>HGNC ID: HGNC:291</p>
            <p>HGNC symbol: ADSL</p>
            <p>entrez_id: 158</p>
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        </notes>
      </fbc:geneProduct>
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        <notes>
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            <p>ENSG: ENSG00000138363</p>
            <p>HGNC ID: HGNC:794</p>
            <p>HGNC symbol: ATIC</p>
            <p>entrez_id: 471</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__20093" fbc:name="G_HGNC:20093" fbc:label="G_HGNC__58__20093">
        <notes>
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            <p>ENSG: ENSG00000185100</p>
            <p>HGNC ID: HGNC:20093</p>
            <p>HGNC symbol: ADSS1</p>
            <p>entrez_id: 122622</p>
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        </notes>
      </fbc:geneProduct>
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        <notes>
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            <p>ENSG: ENSG00000035687</p>
            <p>HGNC ID: HGNC:292</p>
            <p>HGNC symbol: ADSS2</p>
            <p>entrez_id: 159</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4693" fbc:name="G_HGNC:4693" fbc:label="G_HGNC__58__4693">
        <notes>
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            <p>ENSG: ENSG00000143774</p>
            <p>HGNC ID: HGNC:4693</p>
            <p>HGNC symbol: GUK1</p>
            <p>entrez_id: 2987</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__17296" fbc:name="G_HGNC:17296" fbc:label="G_HGNC__58__17296">
        <notes>
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            <p>ENSG: ENSG00000048392</p>
            <p>HGNC ID: HGNC:17296</p>
            <p>HGNC symbol: RRM2B</p>
            <p>entrez_id: 50484</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10452" fbc:name="G_HGNC:10452" fbc:label="G_HGNC__58__10452">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000171848</p>
            <p>HGNC ID: HGNC:10452</p>
            <p>HGNC symbol: RRM2</p>
            <p>entrez_id: 6241</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10451" fbc:name="G_HGNC:10451" fbc:label="G_HGNC__58__10451">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000167325</p>
            <p>HGNC ID: HGNC:10451</p>
            <p>HGNC symbol: RRM1</p>
            <p>entrez_id: 6240</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__20091" fbc:name="G_HGNC:20091" fbc:label="G_HGNC__58__20091">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000140057</p>
            <p>HGNC ID: HGNC:20091</p>
            <p>HGNC symbol: AK7</p>
            <p>entrez_id: 122481</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__365" fbc:name="G_HGNC:365" fbc:label="G_HGNC__58__365">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000154027</p>
            <p>HGNC ID: HGNC:365</p>
            <p>HGNC symbol: AK5</p>
            <p>entrez_id: 26289</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__361" fbc:name="G_HGNC:361" fbc:label="G_HGNC__58__361">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000106992</p>
            <p>HGNC ID: HGNC:361</p>
            <p>HGNC symbol: AK1</p>
            <p>entrez_id: 203</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__362" fbc:name="G_HGNC:362" fbc:label="G_HGNC__58__362">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000004455</p>
            <p>HGNC ID: HGNC:362</p>
            <p>HGNC symbol: AK2</p>
            <p>entrez_id: 204</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__1424" fbc:name="G_HGNC:1424" fbc:label="G_HGNC__58__1424">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000084774</p>
            <p>HGNC ID: HGNC:1424</p>
            <p>HGNC symbol: CAD</p>
            <p>entrez_id: 790</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2867" fbc:name="G_HGNC:2867" fbc:label="G_HGNC__58__2867">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000102967</p>
            <p>HGNC ID: HGNC:2867</p>
            <p>HGNC symbol: DHODH</p>
            <p>entrez_id: 1723</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__12563" fbc:name="G_HGNC:12563" fbc:label="G_HGNC__58__12563">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000114491</p>
            <p>HGNC ID: HGNC:12563</p>
            <p>HGNC symbol: UMPS</p>
            <p>entrez_id: 7372</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__18170" fbc:name="G_HGNC:18170" fbc:label="G_HGNC__58__18170">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000162368</p>
            <p>HGNC ID: HGNC:18170</p>
            <p>HGNC symbol: CMPK1</p>
            <p>entrez_id: 51727</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__12441" fbc:name="G_HGNC:12441" fbc:label="G_HGNC__58__12441">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000176890</p>
            <p>HGNC ID: HGNC:12441</p>
            <p>HGNC symbol: TYMS</p>
            <p>entrez_id: 7298</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__3061" fbc:name="G_HGNC:3061" fbc:label="G_HGNC__58__3061">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000168393</p>
            <p>HGNC ID: HGNC:3061</p>
            <p>HGNC symbol: DTYMK</p>
            <p>entrez_id: 1841</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__20461" fbc:name="G_HGNC:20461" fbc:label="G_HGNC__58__20461">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000143156</p>
            <p>HGNC ID: HGNC:20461</p>
            <p>HGNC symbol: NME7</p>
            <p>entrez_id: 29922</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__20567" fbc:name="G_HGNC:20567" fbc:label="G_HGNC__58__20567">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000172113</p>
            <p>HGNC ID: HGNC:20567</p>
            <p>HGNC symbol: NME6</p>
            <p>entrez_id: 10201</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7851" fbc:name="G_HGNC:7851" fbc:label="G_HGNC__58__7851">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000103024</p>
            <p>HGNC ID: HGNC:7851</p>
            <p>HGNC symbol: NME3</p>
            <p>entrez_id: 4832</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7850" fbc:name="G_HGNC:7850" fbc:label="G_HGNC__58__7850">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000243678</p>
            <p>HGNC ID: HGNC:7850</p>
            <p>HGNC symbol: NME2</p>
            <p>entrez_id: 4831</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__7849" fbc:name="G_HGNC:7849" fbc:label="G_HGNC__58__7849">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000239672</p>
            <p>HGNC ID: HGNC:7849</p>
            <p>HGNC symbol: NME1</p>
            <p>entrez_id: 4830</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2519" fbc:name="G_HGNC:2519" fbc:label="G_HGNC__58__2519">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000171793</p>
            <p>HGNC ID: HGNC:2519</p>
            <p>HGNC symbol: CTPS1</p>
            <p>entrez_id: 1503</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2520" fbc:name="G_HGNC:2520" fbc:label="G_HGNC__58__2520">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000047230</p>
            <p>HGNC ID: HGNC:2520</p>
            <p>HGNC symbol: CTPS2</p>
            <p>entrez_id: 56474</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4335" fbc:name="G_HGNC:4335" fbc:label="G_HGNC__58__4335">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000148672</p>
            <p>HGNC ID: HGNC:4335</p>
            <p>HGNC symbol: GLUD1</p>
            <p>entrez_id: 2746</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4336" fbc:name="G_HGNC:4336" fbc:label="G_HGNC__58__4336">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000182890</p>
            <p>HGNC ID: HGNC:4336</p>
            <p>HGNC symbol: GLUD2</p>
            <p>entrez_id: 2747</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4432" fbc:name="G_HGNC:4432" fbc:label="G_HGNC__58__4432">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000120053</p>
            <p>HGNC ID: HGNC:4432</p>
            <p>HGNC symbol: GOT1</p>
            <p>entrez_id: 2805</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__4433" fbc:name="G_HGNC:4433" fbc:label="G_HGNC__58__4433">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000125166</p>
            <p>HGNC ID: HGNC:4433</p>
            <p>HGNC symbol: GOT2</p>
            <p>entrez_id: 2806</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10982" fbc:name="G_HGNC:10982" fbc:label="G_HGNC__58__10982">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000115840</p>
            <p>HGNC ID: HGNC:10982</p>
            <p>HGNC symbol: SLC25A12</p>
            <p>entrez_id: 8604</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10983" fbc:name="G_HGNC:10983" fbc:label="G_HGNC__58__10983">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000004864</p>
            <p>HGNC ID: HGNC:10983</p>
            <p>HGNC symbol: SLC25A13</p>
            <p>entrez_id: 10165</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2323" fbc:name="G_HGNC:2323" fbc:label="G_HGNC__58__2323">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000021826</p>
            <p>HGNC ID: HGNC:2323</p>
            <p>HGNC symbol: CPS1</p>
            <p>entrez_id: 1373</p>
          </html>
        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__8512" fbc:name="G_HGNC:8512" fbc:label="G_HGNC__58__8512">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000036473</p>
            <p>HGNC ID: HGNC:8512</p>
            <p>HGNC symbol: OTC</p>
            <p>entrez_id: 5009</p>
          </html>
        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10985" fbc:name="G_HGNC:10985" fbc:label="G_HGNC__58__10985">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000102743</p>
            <p>HGNC ID: HGNC:10985</p>
            <p>HGNC symbol: SLC25A15</p>
            <p>entrez_id: 10166</p>
          </html>
        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__22921" fbc:name="G_HGNC:22921" fbc:label="G_HGNC__58__22921">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000120329</p>
            <p>HGNC ID: HGNC:22921</p>
            <p>HGNC symbol: SLC25A2</p>
            <p>entrez_id: 83884</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__758" fbc:name="G_HGNC:758" fbc:label="G_HGNC__58__758">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000130707</p>
            <p>HGNC ID: HGNC:758</p>
            <p>HGNC symbol: ASS1</p>
            <p>entrez_id: 445</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__746" fbc:name="G_HGNC:746" fbc:label="G_HGNC__58__746">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000126522</p>
            <p>HGNC ID: HGNC:746</p>
            <p>HGNC symbol: ASL</p>
            <p>entrez_id: 435</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__663" fbc:name="G_HGNC:663" fbc:label="G_HGNC__58__663">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000118520</p>
            <p>HGNC ID: HGNC:663</p>
            <p>HGNC symbol: ARG1</p>
            <p>entrez_id: 383</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__8109" fbc:name="G_HGNC:8109" fbc:label="G_HGNC__58__8109">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000115758</p>
            <p>HGNC ID: HGNC:8109</p>
            <p>HGNC symbol: ODC1</p>
            <p>entrez_id: 4953</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__11296" fbc:name="G_HGNC:11296" fbc:label="G_HGNC__58__11296">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000116649</p>
            <p>HGNC ID: HGNC:11296</p>
            <p>HGNC symbol: SRM</p>
            <p>entrez_id: 6723</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__11123" fbc:name="G_HGNC:11123" fbc:label="G_HGNC__58__11123">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000102172</p>
            <p>HGNC ID: HGNC:11123</p>
            <p>HGNC symbol: SMS</p>
            <p>entrez_id: 6611</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__7413" fbc:name="G_HGNC:7413" fbc:label="G_HGNC__58__7413">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000099810</p>
            <p>HGNC ID: HGNC:7413</p>
            <p>HGNC symbol: MTAP</p>
            <p>entrez_id: 4507</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__626" fbc:name="G_HGNC:626" fbc:label="G_HGNC__58__626">
        <notes>
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            <p>ENSG: ENSG00000198931</p>
            <p>HGNC ID: HGNC:626</p>
            <p>HGNC symbol: APRT</p>
            <p>entrez_id: 353</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__633" fbc:name="G_HGNC:633" fbc:label="G_HGNC__58__633">
        <notes>
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            <p>ENSG: ENSG00000240583</p>
            <p>HGNC ID: HGNC:633</p>
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            <p>ENSG: ENSG00000167580</p>
            <p>HGNC ID: HGNC:634</p>
            <p>HGNC symbol: AQP2</p>
            <p>entrez_id: 359</p>
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            <p>ENSG: ENSG00000161798</p>
            <p>HGNC ID: HGNC:638</p>
            <p>HGNC symbol: AQP5</p>
            <p>entrez_id: 362</p>
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            <p>ENSG: ENSG00000171885</p>
            <p>HGNC ID: HGNC:637</p>
            <p>HGNC symbol: AQP4</p>
            <p>entrez_id: 361</p>
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            <p>ENSG: ENSG00000135517</p>
            <p>HGNC ID: HGNC:7103</p>
            <p>HGNC symbol: MIP</p>
            <p>entrez_id: 4284</p>
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        <notes>
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            <p>ENSG: ENSG00000171766</p>
            <p>HGNC ID: HGNC:4175</p>
            <p>HGNC symbol: GATM</p>
            <p>entrez_id: 2628</p>
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        <notes>
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            <p>ENSG: ENSG00000159423</p>
            <p>HGNC ID: HGNC:406</p>
            <p>HGNC symbol: ALDH4A1</p>
            <p>entrez_id: 8659</p>
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        <notes>
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            <p>ENSG: ENSG00000143811</p>
            <p>HGNC ID: HGNC:30262</p>
            <p>HGNC symbol: PYCR2</p>
            <p>entrez_id: 29920</p>
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        <notes>
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            <p>ENSG: ENSG00000250799</p>
            <p>HGNC ID: HGNC:17325</p>
            <p>HGNC symbol: PRODH2</p>
            <p>entrez_id: 58510</p>
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        <notes>
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            <p>ENSG: ENSG00000070669</p>
            <p>HGNC ID: HGNC:753</p>
            <p>HGNC symbol: ASNS</p>
            <p>entrez_id: 440</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__16448" fbc:name="G_HGNC:16448" fbc:label="G_HGNC__58__16448">
        <notes>
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            <p>ENSG: ENSG00000162174</p>
            <p>HGNC ID: HGNC:16448</p>
            <p>HGNC symbol: ASRGL1</p>
            <p>entrez_id: 80150</p>
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        <notes>
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            <p>ENSG: ENSG00000166183</p>
            <p>HGNC ID: HGNC:20123</p>
            <p>HGNC symbol: ASPG</p>
            <p>entrez_id: 374569</p>
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        <notes>
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            <p>ENSG: ENSG00000116984</p>
            <p>HGNC ID: HGNC:7468</p>
            <p>HGNC symbol: MTR</p>
            <p>entrez_id: 4548</p>
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        <notes>
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            <p>ENSG: ENSG00000168906</p>
            <p>HGNC ID: HGNC:6904</p>
            <p>HGNC symbol: MAT2A</p>
            <p>entrez_id: 4144</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__6905" fbc:name="G_HGNC:6905" fbc:label="G_HGNC__58__6905">
        <notes>
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            <p>ENSG: ENSG00000038274</p>
            <p>HGNC ID: HGNC:6905</p>
            <p>HGNC symbol: MAT2B</p>
            <p>entrez_id: 27430</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__6903" fbc:name="G_HGNC:6903" fbc:label="G_HGNC__58__6903">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000151224</p>
            <p>HGNC ID: HGNC:6903</p>
            <p>HGNC symbol: MAT1A</p>
            <p>entrez_id: 4143</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__257" fbc:name="G_HGNC:257" fbc:label="G_HGNC__58__257">
        <notes>
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            <p>ENSG: ENSG00000156110</p>
            <p>HGNC ID: HGNC:257</p>
            <p>HGNC symbol: ADK</p>
            <p>entrez_id: 132</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__1550" fbc:name="G_HGNC:1550" fbc:label="G_HGNC__58__1550">
        <notes>
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            <p>ENSG: ENSG00000160200</p>
            <p>HGNC ID: HGNC:1550</p>
            <p>HGNC symbol: CBS</p>
            <p>entrez_id: 102724560</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2501" fbc:name="G_HGNC:2501" fbc:label="G_HGNC__58__2501">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000116761</p>
            <p>HGNC ID: HGNC:2501</p>
            <p>HGNC symbol: CTH</p>
            <p>entrez_id: 1491</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__7436" fbc:name="G_HGNC:7436" fbc:label="G_HGNC__58__7436">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000177000</p>
            <p>HGNC ID: HGNC:7436</p>
            <p>HGNC symbol: MTHFR</p>
            <p>entrez_id: 4524</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__3791" fbc:name="G_HGNC:3791" fbc:label="G_HGNC__58__3791">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000110195</p>
            <p>HGNC ID: HGNC:3791</p>
            <p>HGNC symbol: FOLR1</p>
            <p>entrez_id: 2348</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__3795" fbc:name="G_HGNC:3795" fbc:label="G_HGNC__58__3795">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000110203</p>
            <p>HGNC ID: HGNC:3795</p>
            <p>HGNC symbol: FOLR3</p>
            <p>entrez_id: 2352</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__976" fbc:name="G_HGNC:976" fbc:label="G_HGNC__58__976">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000060982</p>
            <p>HGNC ID: HGNC:976</p>
            <p>HGNC symbol: BCAT1</p>
            <p>entrez_id: 586</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__977" fbc:name="G_HGNC:977" fbc:label="G_HGNC__58__977">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000105552</p>
            <p>HGNC ID: HGNC:977</p>
            <p>HGNC symbol: BCAT2</p>
            <p>entrez_id: 587</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__986" fbc:name="G_HGNC:986" fbc:label="G_HGNC__58__986">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000248098</p>
            <p>HGNC ID: HGNC:986</p>
            <p>HGNC symbol: BCKDHA</p>
            <p>entrez_id: 593</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__2698" fbc:name="G_HGNC:2698" fbc:label="G_HGNC__58__2698">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000137992</p>
            <p>HGNC ID: HGNC:2698</p>
            <p>HGNC symbol: DBT</p>
            <p>entrez_id: 1629</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000083123</p>
            <p>HGNC ID: HGNC:987</p>
            <p>HGNC symbol: BCKDHB</p>
            <p>entrez_id: 594</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__6186" fbc:name="G_HGNC:6186" fbc:label="G_HGNC__58__6186">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000128928</p>
            <p>HGNC ID: HGNC:6186</p>
            <p>HGNC symbol: IVD</p>
            <p>entrez_id: 3712</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131844</p>
            <p>HGNC ID: HGNC:6937</p>
            <p>HGNC symbol: MCCC2</p>
            <p>entrez_id: 64087</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000078070</p>
            <p>HGNC ID: HGNC:6936</p>
            <p>HGNC symbol: MCCC1</p>
            <p>entrez_id: 56922</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000148090</p>
            <p>HGNC ID: HGNC:890</p>
            <p>HGNC symbol: AUH</p>
            <p>entrez_id: 549</p>
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        <notes>
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            <p>ENSG: ENSG00000151498</p>
            <p>HGNC ID: HGNC:87</p>
            <p>HGNC symbol: ACAD8</p>
            <p>entrez_id: 27034</p>
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        <notes>
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            <p>ENSG: ENSG00000117054</p>
            <p>HGNC ID: HGNC:89</p>
            <p>HGNC symbol: ACADM</p>
            <p>entrez_id: 34</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000084754</p>
            <p>HGNC ID: HGNC:4801</p>
            <p>HGNC symbol: HADHA</p>
            <p>entrez_id: 3030</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000138029</p>
            <p>HGNC ID: HGNC:4803</p>
            <p>HGNC symbol: HADHB</p>
            <p>entrez_id: 3032</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000127884</p>
            <p>HGNC ID: HGNC:3151</p>
            <p>HGNC symbol: ECHS1</p>
            <p>entrez_id: 1892</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000106049</p>
            <p>HGNC ID: HGNC:4907</p>
            <p>HGNC symbol: HIBADH</p>
            <p>entrez_id: 11112</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000137124</p>
            <p>HGNC ID: HGNC:407</p>
            <p>HGNC symbol: ALDH1B1</p>
            <p>entrez_id: 219</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000143149</p>
            <p>HGNC ID: HGNC:412</p>
            <p>HGNC symbol: ALDH9A1</p>
            <p>entrez_id: 223</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000164904</p>
            <p>HGNC ID: HGNC:877</p>
            <p>HGNC symbol: ALDH7A1</p>
            <p>entrez_id: 501</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000111275</p>
            <p>HGNC ID: HGNC:404</p>
            <p>HGNC symbol: ALDH2</p>
            <p>entrez_id: 217</p>
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        </notes>
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        <notes>
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            <p>ENSG: ENSG00000072210</p>
            <p>HGNC ID: HGNC:403</p>
            <p>HGNC symbol: ALDH3A2</p>
            <p>entrez_id: 224</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000119711</p>
            <p>HGNC ID: HGNC:7179</p>
            <p>HGNC symbol: ALDH6A1</p>
            <p>entrez_id: 4329</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000124370</p>
            <p>HGNC ID: HGNC:16732</p>
            <p>HGNC symbol: MCEE</p>
            <p>entrez_id: 84693</p>
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        </notes>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000146085</p>
            <p>HGNC ID: HGNC:7526</p>
            <p>HGNC symbol: MMUT</p>
            <p>entrez_id: 4594</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000092621</p>
            <p>HGNC ID: HGNC:8923</p>
            <p>HGNC symbol: PHGDH</p>
            <p>entrez_id: 26227</p>
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        <notes>
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            <p>ENSG: ENSG00000135069</p>
            <p>HGNC ID: HGNC:19129</p>
            <p>HGNC symbol: PSAT1</p>
            <p>entrez_id: 29968</p>
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        <notes>
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            <p>ENSG: ENSG00000146733</p>
            <p>HGNC ID: HGNC:9577</p>
            <p>HGNC symbol: PSPH</p>
            <p>entrez_id: 5723</p>
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        <notes>
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            <p>ENSG: ENSG00000176974</p>
            <p>HGNC ID: HGNC:10850</p>
            <p>HGNC symbol: SHMT1</p>
            <p>entrez_id: 6470</p>
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            <p>HGNC ID: HGNC:10691</p>
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            <p>HGNC ID: HGNC:4552</p>
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            <p>HGNC ID: HGNC:18062</p>
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            <p>entrez_id: 84706</p>
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            <p>HGNC ID: HGNC:10852</p>
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            <p>entrez_id: 6472</p>
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            <p>HGNC ID: HGNC:29683</p>
            <p>HGNC symbol: SLC25A32</p>
            <p>entrez_id: 81034</p>
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            <p>ENSG: ENSG00000228716</p>
            <p>HGNC ID: HGNC:2861</p>
            <p>HGNC symbol: DHFR</p>
            <p>entrez_id: 1719</p>
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            <p>HGNC ID: HGNC:21055</p>
            <p>HGNC symbol: MTHFD1L</p>
            <p>entrez_id: 25902</p>
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            <p>HGNC ID: HGNC:7432</p>
            <p>HGNC symbol: MTHFD1</p>
            <p>entrez_id: 4522</p>
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            <p>ENSG: ENSG00000065911</p>
            <p>HGNC ID: HGNC:7434</p>
            <p>HGNC symbol: MTHFD2</p>
            <p>entrez_id: 10797</p>
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            <p>ENSG: ENSG00000136010</p>
            <p>HGNC ID: HGNC:26777</p>
            <p>HGNC symbol: ALDH1L2</p>
            <p>entrez_id: 160428</p>
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            <p>ENSG: ENSG00000144908</p>
            <p>HGNC ID: HGNC:3978</p>
            <p>HGNC symbol: ALDH1L1</p>
            <p>entrez_id: 10840</p>
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        <notes>
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            <p>ENSG: ENSG00000163738</p>
            <p>HGNC ID: HGNC:31865</p>
            <p>HGNC symbol: MTHFD2L</p>
            <p>entrez_id: 441024</p>
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            <p>ENSG: ENSG00000120437</p>
            <p>HGNC ID: HGNC:94</p>
            <p>HGNC symbol: ACAT2</p>
            <p>entrez_id: 39</p>
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        <notes>
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            <p>ENSG: ENSG00000112972</p>
            <p>HGNC ID: HGNC:5007</p>
            <p>HGNC symbol: HMGCS1</p>
            <p>entrez_id: 3157</p>
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        <notes>
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            <p>ENSG: ENSG00000076555</p>
            <p>HGNC ID: HGNC:85</p>
            <p>HGNC symbol: ACACB</p>
            <p>entrez_id: 32</p>
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        <notes>
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            <p>ENSG: ENSG00000278540</p>
            <p>HGNC ID: HGNC:84</p>
            <p>HGNC symbol: ACACA</p>
            <p>entrez_id: 31</p>
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        <notes>
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            <p>ENSG: ENSG00000169710</p>
            <p>HGNC ID: HGNC:3594</p>
            <p>HGNC symbol: FASN</p>
            <p>entrez_id: 2194</p>
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        <notes>
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            <p>ENSG: ENSG00000151726</p>
            <p>HGNC ID: HGNC:3569</p>
            <p>HGNC symbol: ACSL1</p>
            <p>entrez_id: 2180</p>
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        <notes>
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            <p>ENSG: ENSG00000123983</p>
            <p>HGNC ID: HGNC:3570</p>
            <p>HGNC symbol: ACSL3</p>
            <p>entrez_id: 2181</p>
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        <notes>
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            <p>ENSG: ENSG00000068366</p>
            <p>HGNC ID: HGNC:3571</p>
            <p>HGNC symbol: ACSL4</p>
            <p>entrez_id: 2182</p>
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        <notes>
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            <p>ENSG: ENSG00000164398</p>
            <p>HGNC ID: HGNC:16496</p>
            <p>HGNC symbol: ACSL6</p>
            <p>entrez_id: 23305</p>
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        <notes>
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            <p>ENSG: ENSG00000169169</p>
            <p>HGNC ID: HGNC:18540</p>
            <p>HGNC symbol: CPT1C</p>
            <p>entrez_id: 126129</p>
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        <notes>
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            <p>ENSG: ENSG00000205560</p>
            <p>HGNC ID: HGNC:2329</p>
            <p>HGNC symbol: CPT1B</p>
            <p>entrez_id: 1375</p>
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        <notes>
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            <p>ENSG: ENSG00000110090</p>
            <p>HGNC ID: HGNC:2328</p>
            <p>HGNC symbol: CPT1A</p>
            <p>entrez_id: 1374</p>
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        <notes>
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            <p>ENSG: ENSG00000178537</p>
            <p>HGNC ID: HGNC:1421</p>
            <p>HGNC symbol: SLC25A20</p>
            <p>entrez_id: 788</p>
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        <notes>
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            <p>ENSG: ENSG00000157184</p>
            <p>HGNC ID: HGNC:2330</p>
            <p>HGNC symbol: CPT2</p>
            <p>entrez_id: 1376</p>
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            <p>ENSG: ENSG00000115361</p>
            <p>HGNC ID: HGNC:88</p>
            <p>HGNC symbol: ACADL</p>
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        <notes>
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            <p>ENSG: ENSG00000167315</p>
            <p>HGNC ID: HGNC:83</p>
            <p>HGNC symbol: ACAA2</p>
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            <p>ENSG: ENSG00000072778</p>
            <p>HGNC ID: HGNC:92</p>
            <p>HGNC symbol: ACADVL</p>
            <p>entrez_id: 37</p>
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        <notes>
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            <p>HGNC ID: HGNC:13444</p>
            <p>HGNC symbol: SLC2A10</p>
            <p>entrez_id: 81031</p>
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            <p>HGNC ID: HGNC:23155</p>
            <p>HGNC symbol: SLC5A10</p>
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            <p>HGNC ID: HGNC:11010</p>
            <p>HGNC symbol: SLC2A5</p>
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        <notes>
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            <p>HGNC ID: HGNC:15956</p>
            <p>HGNC symbol: SLC2A13</p>
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            <p>ENSG: ENSG00000117834</p>
            <p>HGNC ID: HGNC:22146</p>
            <p>HGNC symbol: SLC5A9</p>
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            <p>ENSG: ENSG00000198743</p>
            <p>HGNC ID: HGNC:11038</p>
            <p>HGNC symbol: SLC5A3</p>
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            <p>ENSG: ENSG00000173262</p>
            <p>HGNC ID: HGNC:18301</p>
            <p>HGNC symbol: SLC2A14</p>
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            <p>ENSG: ENSG00000115665</p>
            <p>HGNC ID: HGNC:14025</p>
            <p>HGNC symbol: SLC5A7</p>
            <p>entrez_id: 60482</p>
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            <p>ENSG: ENSG00000100191</p>
            <p>HGNC ID: HGNC:11039</p>
            <p>HGNC symbol: SLC5A4</p>
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            <p>ENSG: ENSG00000160326</p>
            <p>HGNC ID: HGNC:11011</p>
            <p>HGNC symbol: SLC2A6</p>
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            <p>ENSG: ENSG00000105641</p>
            <p>HGNC ID: HGNC:11040</p>
            <p>HGNC symbol: SLC5A5</p>
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            <p>HGNC ID: HGNC:14239</p>
            <p>HGNC symbol: SLC2A11</p>
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            <p>ENSG: ENSG00000059804</p>
            <p>HGNC ID: HGNC:11007</p>
            <p>HGNC symbol: SLC2A3</p>
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        <notes>
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            <p>ENSG: ENSG00000138074</p>
            <p>HGNC ID: HGNC:11041</p>
            <p>HGNC symbol: SLC5A6</p>
            <p>entrez_id: 8884</p>
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        <notes>
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            <p>ENSG: ENSG00000109667</p>
            <p>HGNC ID: HGNC:13446</p>
            <p>HGNC symbol: SLC2A9</p>
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            <p>HGNC ID: HGNC:11036</p>
            <p>HGNC symbol: SLC5A1</p>
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            <p>HGNC ID: HGNC:23091</p>
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            <p>HGNC ID: HGNC:18067</p>
            <p>HGNC symbol: SLC2A12</p>
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            <p>HGNC ID: HGNC:28750</p>
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            <p>ENSG: ENSG00000256870</p>
            <p>HGNC ID: HGNC:19119</p>
            <p>HGNC symbol: SLC5A8</p>
            <p>entrez_id: 160728</p>
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            <p>ENSG: ENSG00000136856</p>
            <p>HGNC ID: HGNC:13812</p>
            <p>HGNC symbol: SLC2A8</p>
            <p>entrez_id: 29988</p>
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            <p>HGNC ID: HGNC:11005</p>
            <p>HGNC symbol: SLC2A1</p>
            <p>entrez_id: 6513</p>
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            <p>ENSG: ENSG00000140675</p>
            <p>HGNC ID: HGNC:11037</p>
            <p>HGNC symbol: SLC5A2</p>
            <p>entrez_id: 6524</p>
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            <p>ENSG: ENSG00000197241</p>
            <p>HGNC ID: HGNC:13445</p>
            <p>HGNC symbol: SLC2A7</p>
            <p>entrez_id: 155184</p>
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            <p>ENSG: ENSG00000163581</p>
            <p>HGNC ID: HGNC:11006</p>
            <p>HGNC symbol: SLC2A2</p>
            <p>entrez_id: 6514</p>
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            <p>ENSG: ENSG00000181856</p>
            <p>HGNC ID: HGNC:11009</p>
            <p>HGNC symbol: SLC2A4</p>
            <p>entrez_id: 6517</p>
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            <p>ENSG: ENSG00000139209</p>
            <p>HGNC ID: HGNC:14679</p>
            <p>HGNC symbol: SLC38A4</p>
            <p>entrez_id: 55089</p>
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            <p>ENSG: ENSG00000017483</p>
            <p>HGNC ID: HGNC:18070</p>
            <p>HGNC symbol: SLC38A5</p>
            <p>entrez_id: 92745</p>
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            <p>ENSG: ENSG00000164363</p>
            <p>HGNC ID: HGNC:26441</p>
            <p>HGNC symbol: SLC6A18</p>
            <p>entrez_id: 348932</p>
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        <notes>
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            <p>ENSG: ENSG00000111371</p>
            <p>HGNC ID: HGNC:13447</p>
            <p>HGNC symbol: SLC38A1</p>
            <p>entrez_id: 81539</p>
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            <p>ENSG: ENSG00000147003</p>
            <p>HGNC ID: HGNC:29437</p>
            <p>HGNC symbol: CLTRN</p>
            <p>entrez_id: 57393</p>
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        <notes>
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            <p>ENSG: ENSG00000268104</p>
            <p>HGNC ID: HGNC:11047</p>
            <p>HGNC symbol: SLC6A14</p>
            <p>entrez_id: 11254</p>
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        <notes>
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            <p>ENSG: ENSG00000174358</p>
            <p>HGNC ID: HGNC:27960</p>
            <p>HGNC symbol: SLC6A19</p>
            <p>entrez_id: 340024</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__13448" fbc:name="G_HGNC:13448" fbc:label="G_HGNC__58__13448">
        <notes>
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            <p>ENSG: ENSG00000134294</p>
            <p>HGNC ID: HGNC:13448</p>
            <p>HGNC symbol: SLC38A2</p>
            <p>entrez_id: 54407</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__18044" fbc:name="G_HGNC:18044" fbc:label="G_HGNC__58__18044">
        <notes>
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            <p>ENSG: ENSG00000188338</p>
            <p>HGNC ID: HGNC:18044</p>
            <p>HGNC symbol: SLC38A3</p>
            <p>entrez_id: 10991</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__9225" fbc:name="G_HGNC:9225" fbc:label="G_HGNC__58__9225">
        <notes>
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            <p>ENSG: ENSG00000149150</p>
            <p>HGNC ID: HGNC:9225</p>
            <p>HGNC symbol: SLC43A1</p>
            <p>entrez_id: 8501</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__3793" fbc:name="G_HGNC:3793" fbc:label="G_HGNC__58__3793">
        <notes>
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            <p>ENSG: ENSG00000165457</p>
            <p>HGNC ID: HGNC:3793</p>
            <p>HGNC symbol: FOLR2</p>
            <p>entrez_id: 2350</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__11060" fbc:name="G_HGNC:11060" fbc:label="G_HGNC__58__11060">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000003989</p>
            <p>HGNC ID: HGNC:11060</p>
            <p>HGNC symbol: SLC7A2</p>
            <p>entrez_id: 6542</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__11061" fbc:name="G_HGNC:11061" fbc:label="G_HGNC__58__11061">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000165349</p>
            <p>HGNC ID: HGNC:11061</p>
            <p>HGNC symbol: SLC7A3</p>
            <p>entrez_id: 84889</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__11057" fbc:name="G_HGNC:11057" fbc:label="G_HGNC__58__11057">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000139514</p>
            <p>HGNC ID: HGNC:11057</p>
            <p>HGNC symbol: SLC7A1</p>
            <p>entrez_id: 6541</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000112394</p>
            <p>HGNC ID: HGNC:17027</p>
            <p>HGNC symbol: SLC16A10</p>
            <p>entrez_id: 117247</p>
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        </notes>
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      <fbc:geneProduct fbc:id="G_HGNC__58__18761" fbc:name="G_HGNC:18761" fbc:label="G_HGNC__58__18761">
        <notes>
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            <p>ENSG: ENSG00000123643</p>
            <p>HGNC ID: HGNC:18761</p>
            <p>HGNC symbol: SLC36A1</p>
            <p>entrez_id: 206358</p>
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        <notes>
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            <p>ENSG: ENSG00000130234</p>
            <p>HGNC ID: HGNC:13557</p>
            <p>HGNC symbol: ACE2</p>
            <p>entrez_id: 59272</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000196517</p>
            <p>HGNC ID: HGNC:11056</p>
            <p>HGNC symbol: SLC6A9</p>
            <p>entrez_id: 6536</p>
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        <notes>
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            <p>ENSG: ENSG00000186335</p>
            <p>HGNC ID: HGNC:18762</p>
            <p>HGNC symbol: SLC36A2</p>
            <p>entrez_id: 153201</p>
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        <notes>
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            <p>ENSG: ENSG00000165970</p>
            <p>HGNC ID: HGNC:11051</p>
            <p>HGNC symbol: SLC6A5</p>
            <p>entrez_id: 9152</p>
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        <notes>
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            <p>ENSG: ENSG00000135218</p>
            <p>HGNC ID: HGNC:1663</p>
            <p>HGNC symbol: CD36</p>
            <p>entrez_id: 948</p>
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        <notes>
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            <p>ENSG: ENSG00000130304</p>
            <p>HGNC ID: HGNC:10995</p>
            <p>HGNC symbol: SLC27A1</p>
            <p>entrez_id: 376497</p>
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        <notes>
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            <p>ENSG: ENSG00000167114</p>
            <p>HGNC ID: HGNC:10998</p>
            <p>HGNC symbol: SLC27A4</p>
            <p>entrez_id: 10999</p>
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        <notes>
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            <p>ENSG: ENSG00000197375</p>
            <p>HGNC ID: HGNC:10969</p>
            <p>HGNC symbol: SLC22A5</p>
            <p>entrez_id: 6584</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000141526</p>
            <p>HGNC ID: HGNC:10924</p>
            <p>HGNC symbol: SLC16A3</p>
            <p>entrez_id: 9123</p>
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        <notes>
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            <p>ENSG: ENSG00000100156</p>
            <p>HGNC ID: HGNC:16270</p>
            <p>HGNC symbol: SLC16A8</p>
            <p>entrez_id: 23539</p>
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        <notes>
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            <p>ENSG: ENSG00000118596</p>
            <p>HGNC ID: HGNC:10928</p>
            <p>HGNC symbol: SLC16A7</p>
            <p>entrez_id: 9194</p>
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        <notes>
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            <p>ENSG: ENSG00000132874</p>
            <p>HGNC ID: HGNC:10919</p>
            <p>HGNC symbol: SLC14A2</p>
            <p>entrez_id: 8170</p>
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        <notes>
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            <p>ENSG: ENSG00000141469</p>
            <p>HGNC ID: HGNC:10918</p>
            <p>HGNC symbol: SLC14A1</p>
            <p>entrez_id: 6563</p>
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        <notes>
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            <p>ENSG: ENSG00000174669</p>
            <p>HGNC ID: HGNC:11004</p>
            <p>HGNC symbol: SLC29A2</p>
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        <notes>
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            <p>ENSG: ENSG00000112759</p>
            <p>HGNC ID: HGNC:11003</p>
            <p>HGNC symbol: SLC29A1</p>
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        <notes>
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            <p>ENSG: ENSG00000180773</p>
            <p>HGNC ID: HGNC:19660</p>
            <p>HGNC symbol: SLC36A4</p>
            <p>entrez_id: 120103</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000079215</p>
            <p>HGNC ID: HGNC:10941</p>
            <p>HGNC symbol: SLC1A3</p>
            <p>entrez_id: 6507</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000105143</p>
            <p>HGNC ID: HGNC:10944</p>
            <p>HGNC symbol: SLC1A6</p>
            <p>entrez_id: 6511</p>
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        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000162383</p>
            <p>HGNC ID: HGNC:10945</p>
            <p>HGNC symbol: SLC1A7</p>
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        <notes>
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            <p>ENSG: ENSG00000106688</p>
            <p>HGNC ID: HGNC:10939</p>
            <p>HGNC symbol: SLC1A1</p>
            <p>entrez_id: 6505</p>
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        <notes>
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            <p>ENSG: ENSG00000110436</p>
            <p>HGNC ID: HGNC:10940</p>
            <p>HGNC symbol: SLC1A2</p>
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        <notes>
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            <p>ENSG: ENSG00000130005</p>
            <p>HGNC ID: HGNC:4136</p>
            <p>HGNC symbol: GAMT</p>
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            <p>ENSG: ENSG00000104879</p>
            <p>HGNC ID: HGNC:1994</p>
            <p>HGNC symbol: CKM</p>
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            <p>HGNC ID: HGNC:1991</p>
            <p>HGNC symbol: CKB</p>
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            <p>HGNC ID: HGNC:28577</p>
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            <p>HGNC ID: HGNC:3974</p>
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            <p>HGNC ID: HGNC:29268</p>
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            <p>HGNC ID: HGNC:17929</p>
            <p>HGNC symbol: AADAT</p>
            <p>entrez_id: 51166</p>
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            <p>HGNC ID: HGNC:4189</p>
            <p>HGNC symbol: GCDH</p>
            <p>entrez_id: 2639</p>
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            <p>HGNC ID: HGNC:23408</p>
            <p>HGNC symbol: ECHDC2</p>
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            <p>HGNC ID: HGNC:5008</p>
            <p>HGNC symbol: HMGCS2</p>
            <p>entrez_id: 3158</p>
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            <p>HGNC ID: HGNC:1795</p>
            <p>HGNC symbol: CDO1</p>
            <p>entrez_id: 1036</p>
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            <p>HGNC ID: HGNC:11573</p>
            <p>HGNC symbol: TAT</p>
            <p>entrez_id: 6898</p>
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            <p>HGNC ID: HGNC:5147</p>
            <p>HGNC symbol: HPD</p>
            <p>entrez_id: 3242</p>
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            <p>HGNC ID: HGNC:4892</p>
            <p>HGNC symbol: HGD</p>
            <p>entrez_id: 3081</p>
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            <p>ENSG: ENSG00000100577</p>
            <p>HGNC ID: HGNC:4643</p>
            <p>HGNC symbol: GSTZ1</p>
            <p>entrez_id: 2954</p>
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        <notes>
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            <p>HGNC ID: HGNC:3579</p>
            <p>HGNC symbol: FAH</p>
            <p>entrez_id: 2184</p>
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        <notes>
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            <p>ENSG: ENSG00000081760</p>
            <p>HGNC ID: HGNC:21298</p>
            <p>HGNC symbol: AACS</p>
            <p>entrez_id: 65985</p>
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        <notes>
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            <p>ENSG: ENSG00000103257</p>
            <p>HGNC ID: HGNC:11063</p>
            <p>HGNC symbol: SLC7A5</p>
            <p>entrez_id: 8140</p>
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        <notes>
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            <p>ENSG: ENSG00000115919</p>
            <p>HGNC ID: HGNC:6469</p>
            <p>HGNC symbol: KYNU</p>
            <p>entrez_id: 8942</p>
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        <notes>
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            <p>ENSG: ENSG00000117009</p>
            <p>HGNC ID: HGNC:6381</p>
            <p>HGNC symbol: KMO</p>
            <p>entrez_id: 8564</p>
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        <notes>
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            <p>HGNC ID: HGNC:4796</p>
            <p>HGNC symbol: HAAO</p>
            <p>entrez_id: 23498</p>
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        <notes>
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            <p>ENSG: ENSG00000153086</p>
            <p>HGNC ID: HGNC:19288</p>
            <p>HGNC symbol: ACMSD</p>
            <p>entrez_id: 130013</p>
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        <notes>
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            <p>HGNC ID: HGNC:14411</p>
            <p>HGNC symbol: SLC25A21</p>
            <p>entrez_id: 89874</p>
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            <p>HGNC ID: HGNC:18155</p>
            <p>HGNC symbol: TXNRD2</p>
            <p>entrez_id: 10587</p>
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        <notes>
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            <p>HGNC ID: HGNC:12437</p>
            <p>HGNC symbol: TXNRD1</p>
            <p>entrez_id: 7296</p>
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            <p>HGNC ID: HGNC:93</p>
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        <notes>
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            <p>HGNC ID: HGNC:4455</p>
            <p>HGNC symbol: GPD1</p>
            <p>entrez_id: 2819</p>
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        <notes>
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            <p>HGNC ID: HGNC:25625</p>
            <p>HGNC symbol: OLAH</p>
            <p>entrez_id: 55301</p>
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        <notes>
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            <p>HGNC ID: HGNC:10547</p>
            <p>HGNC symbol: SC5D</p>
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            <p>HGNC ID: HGNC:3133</p>
            <p>HGNC symbol: EBP</p>
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            <p>HGNC ID: HGNC:5215</p>
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            <p>HGNC ID: HGNC:13398</p>
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            <p>HGNC ID: HGNC:457</p>
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            <p>HGNC ID: HGNC:5006</p>
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            <p>HGNC ID: HGNC:7530</p>
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            <p>HGNC ID: HGNC:9141</p>
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            <p>HGNC ID: HGNC:5387</p>
            <p>HGNC symbol: IDI1</p>
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            <p>HGNC ID: HGNC:23487</p>
            <p>HGNC symbol: IDI2</p>
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            <p>HGNC ID: HGNC:7529</p>
            <p>HGNC symbol: MVD</p>
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            <p>ENSG: ENSG00000152904</p>
            <p>HGNC ID: HGNC:4249</p>
            <p>HGNC symbol: GGPS1</p>
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            <p>HGNC ID: HGNC:11279</p>
            <p>HGNC symbol: SQLE</p>
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            <p>HGNC ID: HGNC:6708</p>
            <p>HGNC symbol: LSS</p>
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            <p>HGNC ID: HGNC:2649</p>
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            <p>HGNC ID: HGNC:6518</p>
            <p>HGNC symbol: LBR</p>
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            <p>ENSG: ENSG00000170271</p>
            <p>HGNC ID: HGNC:1334</p>
            <p>HGNC symbol: FAXDC2</p>
            <p>entrez_id: 10826</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__19340" fbc:name="G_HGNC:19340" fbc:label="G_HGNC__58__19340">
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            <p>ENSG: ENSG00000183305</p>
            <p>HGNC ID: HGNC:19340</p>
            <p>HGNC symbol: MAGEA2B</p>
            <p>entrez_id: 266740</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__10545" fbc:name="G_HGNC:10545" fbc:label="G_HGNC__58__10545">
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            <p>ENSG: ENSG00000052802</p>
            <p>HGNC ID: HGNC:10545</p>
            <p>HGNC symbol: MSMO1</p>
            <p>entrez_id: 6307</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__3629" fbc:name="G_HGNC:3629" fbc:label="G_HGNC__58__3629">
        <notes>
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            <p>ENSG: ENSG00000079459</p>
            <p>HGNC ID: HGNC:3629</p>
            <p>HGNC symbol: FDFT1</p>
            <p>entrez_id: 2222</p>
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      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4378" fbc:name="G_HGNC:4378" fbc:label="G_HGNC__58__4378">
        <notes>
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            <p>ENSG: ENSG00000163655</p>
            <p>HGNC ID: HGNC:4378</p>
            <p>HGNC symbol: GMPS</p>
            <p>entrez_id: 8833</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6052" fbc:name="G_HGNC:6052" fbc:label="G_HGNC__58__6052">
        <notes>
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            <p>ENSG: ENSG00000106348</p>
            <p>HGNC ID: HGNC:6052</p>
            <p>HGNC symbol: IMPDH1</p>
            <p>entrez_id: 3614</p>
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      <fbc:geneProduct fbc:id="G_HGNC__58__6053" fbc:name="G_HGNC:6053" fbc:label="G_HGNC__58__6053">
        <notes>
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            <p>ENSG: ENSG00000178035</p>
            <p>HGNC ID: HGNC:6053</p>
            <p>HGNC symbol: IMPDH2</p>
            <p>entrez_id: 3615</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__20151" fbc:name="G_HGNC:20151" fbc:label="G_HGNC__58__20151">
        <notes>
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            <p>ENSG: ENSG00000179520</p>
            <p>HGNC ID: HGNC:20151</p>
            <p>HGNC symbol: SLC17A8</p>
            <p>entrez_id: 246213</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__16703" fbc:name="G_HGNC:16703" fbc:label="G_HGNC__58__16703">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000091664</p>
            <p>HGNC ID: HGNC:16703</p>
            <p>HGNC symbol: SLC17A6</p>
            <p>entrez_id: 57084</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__16704" fbc:name="G_HGNC:16704" fbc:label="G_HGNC__58__16704">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000104888</p>
            <p>HGNC ID: HGNC:16704</p>
            <p>HGNC symbol: SLC17A7</p>
            <p>entrez_id: 57030</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4119" fbc:name="G_HGNC:4119" fbc:label="G_HGNC__58__4119">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000156958</p>
            <p>HGNC ID: HGNC:4119</p>
            <p>HGNC symbol: GALK2</p>
            <p>entrez_id: 2585</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4118" fbc:name="G_HGNC:4118" fbc:label="G_HGNC__58__4118">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000108479</p>
            <p>HGNC ID: HGNC:4118</p>
            <p>HGNC symbol: GALK1</p>
            <p>entrez_id: 2584</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4135" fbc:name="G_HGNC:4135" fbc:label="G_HGNC__58__4135">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000213930</p>
            <p>HGNC ID: HGNC:4135</p>
            <p>HGNC symbol: GALT</p>
            <p>entrez_id: 2592</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__8905" fbc:name="G_HGNC:8905" fbc:label="G_HGNC__58__8905">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000079739</p>
            <p>HGNC ID: HGNC:8905</p>
            <p>HGNC symbol: PGM1</p>
            <p>entrez_id: 5236</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__8906" fbc:name="G_HGNC:8906" fbc:label="G_HGNC__58__8906">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000169299</p>
            <p>HGNC ID: HGNC:8906</p>
            <p>HGNC symbol: PGM2</p>
            <p>entrez_id: 55276</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4116" fbc:name="G_HGNC:4116" fbc:label="G_HGNC__58__4116">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000117308</p>
            <p>HGNC ID: HGNC:4116</p>
            <p>HGNC symbol: GALE</p>
            <p>entrez_id: 2582</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11064" fbc:name="G_HGNC:11064" fbc:label="G_HGNC__58__11064">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000103064</p>
            <p>HGNC ID: HGNC:11064</p>
            <p>HGNC symbol: SLC7A6</p>
            <p>entrez_id: 9057</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10942" fbc:name="G_HGNC:10942" fbc:label="G_HGNC__58__10942">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000115902</p>
            <p>HGNC ID: HGNC:10942</p>
            <p>HGNC symbol: SLC1A4</p>
            <p>entrez_id: 6509</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11067" fbc:name="G_HGNC:11067" fbc:label="G_HGNC__58__11067">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000021488</p>
            <p>HGNC ID: HGNC:11067</p>
            <p>HGNC symbol: SLC7A9</p>
            <p>entrez_id: 11136</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11065" fbc:name="G_HGNC:11065" fbc:label="G_HGNC__58__11065">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000155465</p>
            <p>HGNC ID: HGNC:11065</p>
            <p>HGNC symbol: SLC7A7</p>
            <p>entrez_id: 9056</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11026" fbc:name="G_HGNC:11026" fbc:label="G_HGNC__58__11026">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000168003</p>
            <p>HGNC ID: HGNC:11026</p>
            <p>HGNC symbol: SLC3A2</p>
            <p>entrez_id: 6520</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__23087" fbc:name="G_HGNC:23087" fbc:label="G_HGNC__58__23087">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000278550</p>
            <p>HGNC ID: HGNC:23087</p>
            <p>HGNC symbol: SLC43A2</p>
            <p>entrez_id: 124935</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11058" fbc:name="G_HGNC:11058" fbc:label="G_HGNC__58__11058">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000130876</p>
            <p>HGNC ID: HGNC:11058</p>
            <p>HGNC symbol: SLC7A10</p>
            <p>entrez_id: 56301</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10971" fbc:name="G_HGNC:10971" fbc:label="G_HGNC__58__10971">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000137204</p>
            <p>HGNC ID: HGNC:10971</p>
            <p>HGNC symbol: SLC22A7</p>
            <p>entrez_id: 10864</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11066" fbc:name="G_HGNC:11066" fbc:label="G_HGNC__58__11066">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000092068</p>
            <p>HGNC ID: HGNC:11066</p>
            <p>HGNC symbol: SLC7A8</p>
            <p>entrez_id: 23428</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11054" fbc:name="G_HGNC:11054" fbc:label="G_HGNC__58__11054">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000011083</p>
            <p>HGNC ID: HGNC:11054</p>
            <p>HGNC symbol: SLC6A7</p>
            <p>entrez_id: 6534</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__30927" fbc:name="G_HGNC:30927" fbc:label="G_HGNC__58__30927">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000163817</p>
            <p>HGNC ID: HGNC:30927</p>
            <p>HGNC symbol: SLC6A20</p>
            <p>entrez_id: 54716</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11025" fbc:name="G_HGNC:11025" fbc:label="G_HGNC__58__11025">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000138079</p>
            <p>HGNC ID: HGNC:11025</p>
            <p>HGNC symbol: SLC3A1</p>
            <p>entrez_id: 6519</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11059" fbc:name="G_HGNC:11059" fbc:label="G_HGNC__58__11059">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000151012</p>
            <p>HGNC ID: HGNC:11059</p>
            <p>HGNC symbol: SLC7A11</p>
            <p>entrez_id: 23657</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__8582" fbc:name="G_HGNC:8582" fbc:label="G_HGNC__58__8582">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000171759</p>
            <p>HGNC ID: HGNC:8582</p>
            <p>HGNC symbol: PAH</p>
            <p>entrez_id: 5053</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__10963" fbc:name="G_HGNC:10963" fbc:label="G_HGNC__58__10963">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000175003</p>
            <p>HGNC ID: HGNC:10963</p>
            <p>HGNC symbol: SLC22A1</p>
            <p>entrez_id: 6580</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__5028" fbc:name="G_HGNC:5028" fbc:label="G_HGNC__58__5028">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000150540</p>
            <p>HGNC ID: HGNC:5028</p>
            <p>HGNC symbol: HNMT</p>
            <p>entrez_id: 3176</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2859" fbc:name="G_HGNC:2859" fbc:label="G_HGNC__58__2859">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000116133</p>
            <p>HGNC ID: HGNC:2859</p>
            <p>HGNC symbol: DHCR24</p>
            <p>entrez_id: 1718</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4093" fbc:name="G_HGNC:4093" fbc:label="G_HGNC__58__4093">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000136750</p>
            <p>HGNC ID: HGNC:4093</p>
            <p>HGNC symbol: GAD2</p>
            <p>entrez_id: 2572</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4799" fbc:name="G_HGNC:4799" fbc:label="G_HGNC__58__4799">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000138796</p>
            <p>HGNC ID: HGNC:4799</p>
            <p>HGNC symbol: HADH</p>
            <p>entrez_id: 3033</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__4800" fbc:name="G_HGNC:4800" fbc:label="G_HGNC__58__4800">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000072506</p>
            <p>HGNC ID: HGNC:4800</p>
            <p>HGNC symbol: HSD17B10</p>
            <p>entrez_id: 3028</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__20910" fbc:name="G_HGNC:20910" fbc:label="G_HGNC__58__20910">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000183077</p>
            <p>HGNC ID: HGNC:20910</p>
            <p>HGNC symbol: AFMID</p>
            <p>entrez_id: 125061</p>
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        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__27269" fbc:name="G_HGNC:27269" fbc:label="G_HGNC__58__27269">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000188676</p>
            <p>HGNC ID: HGNC:27269</p>
            <p>HGNC symbol: IDO2</p>
            <p>entrez_id: 169355</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__6059" fbc:name="G_HGNC:6059" fbc:label="G_HGNC__58__6059">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131203</p>
            <p>HGNC ID: HGNC:6059</p>
            <p>HGNC symbol: IDO1</p>
            <p>entrez_id: 3620</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__11708" fbc:name="G_HGNC:11708" fbc:label="G_HGNC__58__11708">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000151790</p>
            <p>HGNC ID: HGNC:11708</p>
            <p>HGNC symbol: TDO2</p>
            <p>entrez_id: 6999</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__15814" fbc:name="G_HGNC__58__15814" fbc:label="G_HGNC__58__15814">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000131069</p>
            <p>HGNC ID: HGNC:15814</p>
            <p>HGNC symbol: ACSS2</p>
            <p>entrez_id: 55902</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__2342" fbc:name="G_HGNC__58__2342" fbc:label="G_HGNC__58__2342">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000095321</p>
            <p>HGNC ID: HGNC:2342</p>
            <p>HGNC symbol: CRAT</p>
            <p>entrez_id: 1384</p>
          </html>
        </notes>
      </fbc:geneProduct>
      <fbc:geneProduct fbc:id="G_HGNC__58__18355" fbc:name="G_HGNC__58__18355" fbc:label="G_HGNC__58__18355">
        <notes>
          <html xmlns="http://www.w3.org/1999/xhtml">
            <p>ENSG: ENSG00000125246</p>
            <p>HGNC ID: HGNC:18355</p>
            <p>HGNC symbol: CLYBL</p>
            <p>entrez_id: 171425</p>
          </html>
        </notes>
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