view COBRAxy/local/svg metabolic maps/HMRcore_map.svg @ 4:41f35c2f0c7b draft

Uploaded
author luca_milaz
date Wed, 18 Sep 2024 10:59:10 +0000
parents
children
line wrap: on
line source

<?xml version="1.0" encoding="UTF-8" standalone="no"?>
<!-- Generator: Adobe Illustrator 22.0.1, SVG Export Plug-In . SVG Version: 6.00 Build 0)  -->

<svg
   xmlns:dc="http://purl.org/dc/elements/1.1/"
   xmlns:cc="http://creativecommons.org/ns#"
   xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
   xmlns:svg="http://www.w3.org/2000/svg"
   xmlns="http://www.w3.org/2000/svg"
   xmlns:xlink="http://www.w3.org/1999/xlink"
   xmlns:sodipodi="http://sodipodi.sourceforge.net/DTD/sodipodi-0.dtd"
   xmlns:inkscape="http://www.inkscape.org/namespaces/inkscape"
   version="1.1"
   x="0px"
   y="0px"
   viewBox="0 0 1904.8016 1511.2752"
   xml:space="preserve"
   id="svg2"
   inkscape:version="0.91 r13725"
   sodipodi:docname="HMRcoreMap.svg"
   width="1904.8015"
   height="1511.2753"><metadata
     id="metadata2021"><rdf:RDF><cc:Work
         rdf:about=""><dc:format>image/svg+xml</dc:format><dc:type
           rdf:resource="http://purl.org/dc/dcmitype/StillImage" /><dc:title /></cc:Work></rdf:RDF></metadata><defs
     id="defs2019"><sodipodi:namedview
       showguides="true"
       showgrid="true"
       pagecolor="#ffffff"
       inkscape:zoom="1.4702451"
       inkscape:window-y="-8"
       inkscape:window-x="-8"
       inkscape:window-width="1920"
       inkscape:window-maximized="1"
       inkscape:window-height="1017"
       inkscape:snap-page="false"
       inkscape:snap-grids="true"
       inkscape:pageshadow="2"
       inkscape:pageopacity="0.0"
       inkscape:document-units="px"
       inkscape:cy="338.10986"
       inkscape:cx="1343.7768"
       inkscape:current-layer="layer1"
       id="base"
       fit-margin-top="0"
       fit-margin-right="0"
       fit-margin-left="0"
       fit-margin-bottom="0"
       borderopacity="1.0"
       bordercolor="#666666"><inkscape:grid
         type="xygrid"
         originy="72.926308"
         originx="-97.409688"
         id="grid3434"
         dotted="true" /></sodipodi:namedview></defs><sodipodi:namedview
     pagecolor="#ffffff"
     bordercolor="#666666"
     borderopacity="1"
     objecttolerance="10"
     gridtolerance="10"
     guidetolerance="10"
     inkscape:pageopacity="0"
     inkscape:pageshadow="2"
     inkscape:window-width="1920"
     inkscape:window-height="1017"
     id="namedview2017"
     showgrid="false"
     inkscape:zoom="0.44727204"
     inkscape:cx="497.63252"
     inkscape:cy="796.80241"
     inkscape:window-x="-8"
     inkscape:window-y="-8"
     inkscape:window-maximized="1"
     inkscape:current-layer="svg2"
     fit-margin-top="0"
     fit-margin-left="0"
     fit-margin-right="0"
     fit-margin-bottom="0" /><style
     type="text/css"
     id="style4">
	.st0{display:none;}
	.st1{display:inline;}
	.st2{fill:none;stroke:#5AB6E7;stroke-width:7;stroke-linejoin:round;}
	.st3{fill:none;stroke:#5AB6E7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:11.9422,11.9422;}
	.st4{fill:none;stroke:#5AB6E7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:12.1815,12.1815;}
	.st5{font-family:'Helvetica';}
	.st6{font-size:30px;}
	.st7{font-size:39.262px;}
	.st8{fill:none;stroke:#0000FF;stroke-width:30;}
	.st9{fill:none;stroke:#E41A1C;stroke-width:30;}
	.st10{fill:none;stroke:#BEBEBE;stroke-width:30;}
	.st11{stroke:#000000;stroke-width:30;}
	.st12{fill:none;stroke:#BEBEBE;stroke-width:30;stroke-dasharray:30,30;stroke-dashoffset:6;}
	.st13{fill:none;stroke:#000000;stroke-width:1.8444;}
	.st14{fill:none;stroke:#000000;stroke-width:2.1821;}
	.st15{font-family:'Calibri-Bold';}
	.st16{font-size:16px;}
	.st17{font-family:'Calibri';}
	.st18{font-size:10px;}
	.st19{fill:none;stroke:#000000;stroke-width:1.8856;}
	.st20{fill:none;stroke:#000000;stroke-width:1.9459;}
	.st21{fill:none;stroke:#000000;stroke-width:2.2892;}
	.st22{fill:none;stroke:#000000;stroke-width:2.5;}
	.st23{fill:none;stroke:#000000;stroke-width:1.9412;}
	.st24{fill:none;stroke:#000000;stroke-width:1.9661;}
	.st25{fill:none;stroke:#000000;stroke-width:1.0869;}
	.st26{font-size:6.0937px;}
	.st27{fill:none;stroke:#000000;stroke-width:2.0174;}
	.st28{fill:none;stroke:#000000;stroke-width:1.889;}
	.st29{fill:none;stroke:#000000;stroke-width:1.7769;}
	.st30{fill:none;stroke:#000000;stroke-width:1.8717;}
	.st31{fill:none;stroke:#000000;stroke-width:1.6971;}
	.st32{fill:none;stroke:#000000;stroke-width:2.4492;}
	.st33{fill:none;stroke:#000000;stroke-width:2.0366;}
	.st34{fill:none;stroke:#000000;stroke-width:1.5903;}
	.st35{fill:none;stroke:#000000;stroke-width:1.7287;}
	.st36{fill:none;stroke:#000000;stroke-width:1.7741;}
	.st37{fill:none;stroke:#000000;stroke-width:2.2309;}
	.st38{font-size:14px;}
	.st39{fill:none;stroke:#000000;stroke-width:1.7752;}
	.st40{font-size:9.75px;}
	.st41{fill:none;stroke:#000000;stroke-width:1.8816;}
	.st42{fill:none;stroke:#000000;stroke-width:1.8615;}
	.st43{fill:none;stroke:#000000;stroke-width:1.7923;}
	.st44{fill:none;stroke:#000000;stroke-width:1.8691;}
	.st45{fill:none;stroke:#000000;stroke-width:2.823;}
	.st46{fill:none;stroke:#000000;stroke-width:2.3556;}
	.st47{fill:none;stroke:#000000;stroke-width:2.0484;}
	.st48{fill:none;stroke:#000000;stroke-width:1.127;}
	.st49{fill:none;stroke:#000000;stroke-width:1.5383;}
	.st50{fill:none;stroke:#000000;stroke-width:1.4921;}
	.st51{fill:none;stroke:#000000;stroke-width:1.4117;}
	.st52{fill:none;stroke:#000000;stroke-width:1.3787;}
	.st53{fill:none;stroke:#000000;stroke-width:2.2437;}
	.st54{fill:none;stroke:#000000;stroke-width:1.8492;}
	.st55{fill:none;stroke:#000000;stroke-width:1.816;}
	.st56{fill:none;stroke:#000000;stroke-width:2.0159;}
	.st57{fill:none;stroke:#000000;stroke-width:2.0089;}
	.st58{fill:none;stroke:#000000;stroke-width:1.2666;}
	.st59{fill:none;stroke:#000000;stroke-width:1.3186;}
	.st60{fill:none;stroke:#000000;stroke-width:1.2211;}
	.st61{fill:none;stroke:#000000;stroke-width:1.1828;}
	.st62{fill:none;stroke:#000000;stroke-width:2.0699;}
	.st63{fill:none;stroke:#000000;stroke-width:2.1781;}
	.st64{fill:none;stroke:#000000;stroke-width:2.6751;}
	.st65{fill:none;stroke:#000000;stroke-width:3.1636;}
	.st66{fill:none;stroke:#000000;stroke-width:3.3699;}
	.st67{fill:none;stroke:#000000;stroke-width:2.3147;}
	.st68{fill:none;stroke:#000000;stroke-width:2.2203;}
	.st69{fill:none;stroke:#000000;stroke-width:2.2293;}
	.st70{fill:none;stroke:#000000;stroke-width:1.9667;}
	.st71{fill:none;stroke:#000000;stroke-width:2.1341;}
	.st72{fill:none;stroke:#000000;stroke-width:1.5819;}
	.st73{fill:none;stroke:#000000;stroke-width:2.0995;}
	.st74{fill:none;stroke:#000000;stroke-width:2.4348;}
	.st75{fill:none;stroke:#000000;stroke-width:2.3313;}
	.st76{fill:none;stroke:#000000;stroke-width:2.0948;}
	.st77{fill:none;stroke:#000000;stroke-width:2.2352;}
	.st78{fill:none;stroke:#000000;stroke-width:2.3817;}
	.st79{fill:none;stroke:#000000;stroke-width:2.2976;}
	.st80{fill:none;stroke:#000000;stroke-width:2.0951;}
	.st81{fill:none;stroke:#231F20;stroke-width:7;stroke-linejoin:round;stroke-miterlimit:2;}
	.st82{fill:none;stroke:#000000;stroke-width:1.3247;}
	.st83{fill:none;stroke:#000000;stroke-width:1.564;}
	.st84{fill:none;stroke:#000000;stroke-width:2.1156;}
	.st85{fill:none;stroke:#000000;stroke-width:1.3926;}
	.st86{fill:none;stroke:#000000;stroke-width:1.123;}
	.st87{font-size:9.7577px;}
	.st88{font-size:15.6123px;}
	.st89{fill:none;stroke:#000000;stroke-width:2.0926;}
	.st90{fill:none;stroke:#000000;stroke-width:1.7671;}
	.st91{fill:none;stroke:#000000;stroke-width:1.7901;}
	.st92{fill:none;stroke:#000000;stroke-width:1.9212;}
	.st93{fill:none;stroke:#000000;stroke-width:1.3319;}
	.st94{fill:none;stroke:#000000;stroke-width:2.1398;}
	.st95{fill:none;stroke:#000000;stroke-width:1.3641;}
	.st96{fill:none;stroke:#000000;stroke-width:2.216;}
	.st97{fill:none;stroke:#000000;stroke-width:2.341;}
	.st98{fill:none;stroke:#000000;stroke-width:1.2412;}
	.st99{fill:none;stroke:#000000;stroke-width:1.7827;}
	.st100{fill:none;stroke:#000000;stroke-width:1.8658;}
	.st101{fill:none;stroke:#000000;stroke-width:2.4932;}
	.st102{fill:none;stroke:#000000;stroke-width:2.489;}
	.st103{fill:none;stroke:#000000;stroke-width:2.5188;}
	.st104{fill:none;stroke:#000000;stroke-width:2.4962;}
	.st105{fill:none;stroke:#000000;stroke-width:1.6791;}
	.st106{fill:none;stroke:#000000;stroke-width:1.8121;}
	.st107{fill:none;stroke:#000000;stroke-width:1.5802;}
	.st108{fill:none;stroke:#000000;stroke-width:1.5346;}
	.st109{fill:none;stroke:#000000;stroke-width:1.8293;}
	.st110{fill:none;stroke:#000000;stroke-width:1.6126;}
	.st111{fill:none;stroke:#000000;stroke-width:2.5434;}
	.st112{fill:none;stroke:#000000;stroke-width:1.7519;}
	.st113{fill:none;stroke:#000000;stroke-width:1.5283;}
	.st114{fill:none;stroke:#000000;stroke-width:1.8016;}
	.st115{fill:none;stroke:#000000;stroke-width:3.1376;}
	.st116{fill:none;stroke:#000000;stroke-width:1.8065;}
	.st117{fill:none;stroke:#000000;stroke-width:2.1653;}
	.st118{fill:none;stroke:#000000;stroke-width:1.5857;}
	.st119{fill:none;stroke:#000000;stroke-width:2.1349;}
	.st120{fill:none;stroke:#000000;stroke-width:2.3204;}
	.st121{fill:none;stroke:#000000;stroke-width:1.6814;}
	.st122{fill:none;stroke:#000000;stroke-width:2.9048;}
	.st123{fill:none;stroke:#000000;stroke-width:2.2582;}
	.st124{fill:none;stroke:#000000;stroke-width:1.9206;}
	.st125{fill:none;stroke:#000000;stroke-width:2.0975;}
	.st126{fill:none;stroke:#000000;stroke-width:1.1759;}
	.st127{fill:none;stroke:#000000;stroke-width:1.1348;}
	.st128{fill:none;stroke:#000000;stroke-width:2.0031;}
	.st129{fill:none;stroke:#000000;stroke-width:1.966;}
	.st130{fill:none;stroke:#000000;stroke-width:1.822;}
	.st131{fill:none;stroke:#000000;stroke-width:2.3785;}
	.st132{fill:none;stroke:#000000;stroke-width:1.5336;}
	.st133{fill:none;stroke:#000000;stroke-width:1.4989;}
	.st134{fill:none;stroke:#000000;stroke-width:1.8163;}
	.st135{fill:none;stroke:#000000;stroke-width:2.0955;}
	.st136{fill:none;stroke:#000000;stroke-width:2.1429;}
	.st137{fill:none;stroke:#000000;stroke-width:2.1034;}
	.st138{fill:none;stroke:#000000;stroke-width:2.0686;}
	.st139{fill:none;stroke:#000000;stroke-width:1.1187;}
	.st140{fill:none;stroke:#000000;stroke-width:2.3278;}
	.st141{fill:none;stroke:#000000;stroke-width:2.1814;}
	.st142{fill:none;stroke:#000000;stroke-width:2.0648;}
	.st143{fill:none;stroke:#000000;stroke-width:2.5236;}
	.st144{fill:none;stroke:#000000;stroke-width:2.5697;}
	.st145{fill:#786721;stroke:#000000;stroke-width:2.5;}
	.st146{fill:none;stroke:#000000;stroke-width:1.4509;}
	.st147{fill:none;stroke:#000000;stroke-width:1.7529;}
	.st148{fill:none;stroke:#000000;stroke-width:1.9252;}
	.st149{fill:none;stroke:#000000;stroke-width:1.8983;}
	.st150{fill:none;stroke:#000000;stroke-width:1.7735;}
	.st151{fill:none;stroke:#000000;stroke-width:1.5537;}
	.st152{fill:none;stroke:#000000;stroke-width:1.7117;}
	.st153{fill:none;stroke:#000000;stroke-width:1.7429;}
	.st154{fill:none;stroke:#000000;stroke-width:1.639;}
	.st155{fill:none;stroke:#000000;stroke-width:2.4155;}
	.st156{fill:none;stroke:#000000;stroke-width:1.9672;}
	.st157{fill:none;stroke:#000000;stroke-width:2.2231;}
	.st158{fill:none;stroke:#000000;stroke-width:1.8337;}
	.st159{fill:none;stroke:#000000;stroke-width:1.8531;}
	.st160{fill:none;stroke:#000000;stroke-width:2.2256;}
	.st161{fill:none;stroke:#000000;stroke-width:2.0666;}
	.st162{fill:none;stroke:#000000;stroke-width:1.7335;}
	.st163{fill:none;stroke:#000000;stroke-width:1.6847;}
	.st164{fill:none;stroke:#000000;stroke-width:2.4884;}
	.st165{fill:none;stroke:#000000;stroke-width:2.3113;}
	.st166{fill:none;stroke:#000000;stroke-width:2.1555;}
	.st167{fill:none;stroke:#000000;stroke-width:1.9909;}
	.st168{fill:none;stroke:#000000;stroke-width:9.2205;stroke-linecap:round;stroke-linejoin:round;stroke-miterlimit:2;}
	.st169{fill:none;stroke:#000000;stroke-width:2.5668;}
	.st170{fill:none;stroke:#000000;stroke-width:1.9328;}
	.st171{fill:none;stroke:#000000;stroke-width:3.1971;}
	.st172{fill:none;stroke:#000000;stroke-width:3.1373;}
	.st173{font-size:6.5px;}
</style><g
     id="Layer_2"
     transform="translate(-20.6,18.418554)"><g
       id="rect3188_1_"
       class="st0"
       style="display:none"><g
         class="st1"
         id="g8"
         style="display:inline"><polyline
           class="st2"
           points="269.1,669.8 269.1,663.8 275.1,663.8    "
           id="polyline10"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
           class="st3"
           x1="287"
           y1="663.79999"
           x2="1475.2"
           y2="663.79999"
           id="line12"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:11.9422, 11.9422" /><polyline
           class="st2"
           points="1481.2,663.8 1487.2,663.8 1487.2,669.8    "
           id="polyline14"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
           class="st4"
           x1="1487.2"
           y1="682"
           x2="1487.2"
           y2="1138.8"
           id="line16"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:12.1815, 12.1815" /><polyline
           class="st2"
           points="1487.2,1144.9 1487.2,1150.9 1481.2,1150.9    "
           id="polyline18"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
           class="st3"
           x1="1469.3"
           y1="1150.9"
           x2="281"
           y2="1150.9"
           id="line20"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:11.9422, 11.9422" /><polyline
           class="st2"
           points="275.1,1150.9 269.1,1150.9 269.1,1144.9    "
           id="polyline22"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round" /><line
           class="st4"
           x1="269.10001"
           y1="1132.7"
           x2="269.10001"
           y2="675.90002"
           id="line24"
           style="fill:none;stroke:#5ab6e7;stroke-width:7;stroke-linejoin:round;stroke-dasharray:12.1815, 12.1815" /></g></g></g><g
     id="flowRoot3336"
     transform="translate(-20.6,18.418554)" /><g
     id="flowRoot16808"
     transform="translate(-20.6,18.418554)" /><g
     id="flowRoot2749"
     transform="translate(-20.6,18.418554)" /><g
     id="flowRoot3621"
     transform="translate(-20.6,18.418554)" /><g
     id="flowRoot1974"
     transform="translate(-20.6,18.418554)" /><text
     style="font-size:30px;font-family:Helvetica"
     id="text35"
     class="st5 st6"
     x="129.77209"
     y="1429.6542">= Up regulated</text>
<text
     style="font-size:30px;font-family:Helvetica"
     id="text37"
     class="st5 st6"
     x="129.77209"
     y="1504.6542">= Down regulated</text>
<text
     style="font-size:39.26200104px;font-family:Helvetica"
     id="text39"
     class="st5 st7"
     x="-1.9770008"
     y="1365.1874">Legend</text>
<path
     style="fill:none;stroke:#0000ff;stroke-width:30"
     d="m 0,1495.6186 112,0"
     class="st8"
     inkscape:connector-curvature="0"
     id="path6613-3" /><path
     style="fill:none;stroke:#e41a1c;stroke-width:30"
     d="m 0,1420.7186 112,0"
     class="st9"
     inkscape:connector-curvature="0"
     id="path6613-8-6" /><path
     style="fill:none;stroke:#bebebe;stroke-width:30"
     d="m 503.8,1492.0186 112,0"
     class="st10"
     inkscape:connector-curvature="0"
     id="path6613-8-1-0" /><path
     style="stroke:#000000;stroke-width:30"
     d="m 1140.7,1415.1186 112,0"
     class="st11"
     inkscape:connector-curvature="0"
     id="path6613-8-4-9" /><path
     style="fill:none;stroke:#bebebe;stroke-width:30;stroke-dasharray:30, 30;stroke-dashoffset:6"
     d="m 503.8,1417.3186 112,0"
     class="st12"
     inkscape:connector-curvature="0"
     id="path6613-8-2-6" /><text
     style="font-size:30px;font-family:Helvetica"
     id="text46"
     class="st5 st6"
     x="1270.1295"
     y="1423.1249">= Not classified</text>
<text
     style="font-size:30px;font-family:Helvetica"
     id="text48"
     class="st5 st6"
     x="631.3902"
     y="1426.3895">= Not significant</text>
<text
     style="font-size:30px;font-family:Helvetica"
     id="text50"
     class="st5 st6"
     x="631.3902"
     y="1501.3895">= Fold change under threshold</text>
<text
     style="font-size:30px;font-family:Helvetica"
     id="text52"
     class="st5 st6"
     x="1139.6979"
     y="1499.9501">Thickness is proportional to fold change</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.84440005"
     d="m 834.5,332.71855 26.9,-0.1 m -18,-9 c -2.8,5.8 3.1,9.6 3.1,9.6 m 3.1,-0.5 c 5.1,-0.7 4.9,-9.1 4.9,-9.1"
     class="st13"
     inkscape:label="CMPK1_DTYMK"
     inkscape:connector-curvature="0"
     id="R_CMPK1_DTYMK" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 464.9,461.41855 c 2.2,-7.3 2.2,-7.3 2.2,-7.3 l 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="backward PGM"
     inkscape:connector-curvature="0"
     id="B_PGAM2_PGAM1_BPGM_PGAM4_1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text56"
     class="st15 st16"
     x="449.63071"
     y="207.37375">F6P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text58"
     class="st15 st16"
     x="443.9202"
     y="262.58224">F16BP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text60"
     class="st15 st16"
     x="446.7605"
     y="320.19556">GA3P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text62"
     class="st15 st16"
     x="435.38208"
     y="383.34305">1,3BPGA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text64"
     class="st15 st16"
     x="453.15561"
     y="449.14966">3PG</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text66"
     class="st15 st16"
     x="449.81769"
     y="507.42996">2PG</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text68"
     class="st15 st16"
     x="453.76788"
     y="562.48846">PEP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text70"
     class="st15 st16"
     x="456.6004"
     y="614.97485">Pyr</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text72"
     class="st15 st16"
     x="349.18579"
     y="614.4632">Lact</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text74"
     class="st17 st18"
     x="483.3494"
     y="222.37965">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text76"
     class="st17 st18"
     x="484.75418"
     y="235.29225">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text78"
     class="st17 st18"
     x="478.8587"
     y="337.66135">NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text80"
     class="st17 st18"
     x="497.25217"
     y="337.66135">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text82"
     class="st17 st18"
     x="502.2327"
     y="337.66135">Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text84"
     class="st17 st18"
     x="481.2063"
     y="350.90945">NADH+H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text86"
     class="st17 st18"
     x="481.4881"
     y="401.51096">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text88"
     class="st17 st18"
     x="482.81668"
     y="413.79224">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text90"
     class="st17 st18"
     x="481.35968"
     y="575.7132">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text92"
     class="st17 st18"
     x="485.36938"
     y="586.74536">ATP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 460,182.91855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st14"
     inkscape:label="forward GPI "
     inkscape:connector-curvature="0"
     id="F_GPI" /><path
     style="fill:none;stroke:#000000;stroke-width:1.88559997"
     d="m 462.1,159.61855 c 0,23.8 0,23.8 0,23.8"
     class="st19"
     inkscape:label="GPI "
     inkscape:connector-curvature="0"
     id="R_GPI" /><path
     style="fill:none;stroke:#000000;stroke-width:1.94589996"
     d="m 467.2,458.91855 c 0,25.4 0,25.4 0,25.4"
     class="st20"
     inkscape:label="phosphoglycerate mutase"
     inkscape:connector-curvature="0"
     id="R_PGAM2_PGAM1_BPGM_PGAM4_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 465.1,482.61855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st14"
     inkscape:label="forward PGM"
     inkscape:connector-curvature="0"
     id="F_PGAM2_PGAM1_BPGM_PGAM4_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 464.9,516.91855 c 2.2,-7.3 2.2,-7.3 2.2,-7.3 l 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="backward enolase"
     inkscape:connector-curvature="0"
     id="B_ENO1_ENO3_ENO2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text99"
     class="st15 st16"
     x="492.44656"
     y="284.29803">DHAP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.28920007"
     d="m 462.7,265.81855 c 0,31.9 0,31.9 0,31.9 m 0.6,-17.7 20.2,0"
     class="st21"
     inkscape:connector-curvature="0"
     id="R_ALDOC_ALDOB_ALDOA_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 482.4,278.01855 c 6.1,2.2 6.1,2.2 6.1,2.2 l -6.1,2.2 1.5,-2.2 -1.5,-2.2 z m -21.6,17.9 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st22"
     inkscape:connector-curvature="0"
     id="F_ALDOC_ALDOB_ALDOA_2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.94120002"
     d="m 503.2,293.81855 2.4,-4 0.8,-1.3 -4.9,2.1 1.9,0.6 -0.2,2.6 z"
     class="st23"
     sodipodi:nodetypes="cccccc"
     inkscape:label="backward TPI1_TPI1P2 "
     inkscape:connector-curvature="0"
     id="B_TPI1_TPI1P2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.96609998"
     d="m 488.7,300.71855 c -3.2,5.4 -3.2,5.4 -3.2,5.4 l 5,-2.3 -1.9,-0.6 0.1,-2.5 z"
     class="st24"
     inkscape:label="forwardTPI1_TPI1P2 "
     inkscape:connector-curvature="0"
     id="F_TPI1_TPI1P2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.0869"
     d="m 502.6,291.71855 -14.9,13"
     class="st25"
     inkscape:label="TPI1_TPI1P2 "
     inkscape:connector-curvature="0"
     id="R_TPI1_TPI1P2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text106"
     class="st17 st18"
     x="485.7688"
     y="533.16919">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text108"
     class="st17 st26"
     x="491.9993"
     y="535.16919">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text110"
     class="st17 st18"
     x="495.08768"
     y="533.16919">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text112"
     class="st17 st18"
     x="391.7298"
     y="593.52759">NAD</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text114"
     class="st15 st16"
     x="532.302"
     y="158.84834">6Pgl</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text116"
     class="st17 st18"
     x="471.15601"
     y="174.58125">NADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text118"
     class="st15 st16"
     x="598.32654"
     y="159.01485">6PDG</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text120"
     class="st17 st18"
     x="627.64771"
     y="176.58224">NADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text122"
     class="st15 st16"
     x="694.76404"
     y="159.07295">Ru5P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text124"
     class="st15 st16"
     x="777.18494"
     y="174.95485">R5P</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text126"
     class="st17 st18"
     x="754.10773"
     y="199.29225">AMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text128"
     class="st17 st18"
     x="760.08435"
     y="185.74825">ATP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.01740003"
     d="m 588.2,152.11855 c 7.3,2.2 7.3,2.2 7.3,2.2 l -7.3,2.2 1.8,-2.2 -1.8,-2.2 z"
     class="st27"
     inkscape:label="forward H6PD_PGLS "
     inkscape:connector-curvature="0"
     id="F_H6PD_PGLS" /><text
     style="font-size:10px;font-family:Calibri"
     id="text131"
     class="st17 st18"
     x="564.25323"
     y="173.96214">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text133"
     class="st17 st26"
     x="570.4837"
     y="175.96214">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text135"
     class="st17 st18"
     x="573.57251"
     y="173.96214">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text137"
     class="st15 st16"
     x="774.87531"
     y="143.11105">Xil5P</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.88900006"
     d="m 814.5,167.11855 c -5.3,2.4 -5.3,2.4 -5.3,2.4 l 2.8,-4.7 0.2,2 2.3,0.3 z m -1.4,-20.6 c -2.5,-4.8 -2.5,-4.8 -2.5,-4.8 l 5.1,2.6 -2.3,0.2 -0.3,2 z"
     class="st28"
     inkscape:label="forward TKTL1_TKTL2_TKT_2"
     inkscape:connector-curvature="0"
     id="F_TKTL1_TKTL2_TKT_2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.88900006"
     d="m 834,143.41855 c 5.2,-2.5 5.2,-2.5 5.2,-2.5 l -2.6,4.7 -0.3,-2 -2.3,-0.2 z m 3.8,21.6 c 2.6,4.8 2.6,4.8 2.6,4.8 l -5.2,-2.6 2.3,-0.2 0.3,-2 z"
     class="st28"
     inkscape:label="backward TKTL1_TKTL2_TKT_2 "
     inkscape:connector-curvature="0"
     id="B_TKTL1_TKTL2_TKT_2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.77690005"
     d="m 813,144.01855 23.9,22.6 0,0 m -24.8,0.5 23.9,-22.6"
     class="st29"
     inkscape:label="TKTL1_TKTL2_TKT_2 "
     inkscape:connector-curvature="0"
     id="R_TKTL1_TKTL2_TKT_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text142"
     class="st15 st16"
     x="842.75421"
     y="140.81226">Sed7P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text144"
     class="st15 st16"
     x="844.42902"
     y="174.28685">GA3P</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 890,164.31855 c -5.3,2.3 -5.3,2.3 -5.3,2.3 l 2.8,-4.5 0.2,2 2.3,0.2 z m -1.4,-20.1 c -2.5,-4.7 -2.5,-4.7 -2.5,-4.7 l 5.1,2.6 -2.3,0.1 -0.3,2 z"
     class="st30"
     inkscape:label="backward TALDO1 "
     inkscape:connector-curvature="0"
     id="B_TALDO1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 912.3,141.61855 c 5.2,-2.4 5.2,-2.4 5.2,-2.4 l -2.7,4.6 -0.3,-2 -2.2,-0.2 z m 3.9,21.1 c 2.6,4.6 2.6,4.6 2.6,4.6 l -5.2,-2.5 2.3,-0.2 0.3,-1.9 z"
     class="st30"
     inkscape:label="forward TALDO1 "
     inkscape:connector-curvature="0"
     id="F_TALDO1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 888.1,141.41855 26.3,22.8 0,0 m -27.2,0.6 26.3,-22.8"
     class="st30"
     inkscape:label="TALDO1 "
     inkscape:connector-curvature="0"
     id="R_TALDO1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text149"
     class="st15 st16"
     x="922.31085"
     y="174.11154">Ery4P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text151"
     class="st15 st16"
     x="921.73865"
     y="140.67255">F6P</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.69710004"
     d="m 967.5,191.21855 c -5.2,1.9 -5.2,1.9 -5.2,1.9 l 2.7,-3.8 0.2,1.7 2.3,0.2 z m -1.3,-16.9 c -2.4,-3.9 -2.4,-3.9 -2.4,-3.9 l 5,2.2 -2.2,0.1 -0.4,1.6 z"
     class="st31"
     inkscape:label="forward TKTL1_TKTL2_TKT_1 "
     inkscape:connector-curvature="0"
     id="F_TKTL1_TKTL2_TKT_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.69710004"
     d="m 989.2,172.21855 c 5.1,-2 5.1,-2 5.1,-2 l -2.6,3.9 -0.3,-1.7 -2.2,-0.2 z m 3.8,17.8 c 2.5,3.9 2.5,3.9 2.5,3.9 l -5.1,-2.1 2.2,-0.2 0.4,-1.6 z"
     class="st31"
     inkscape:label="backward TKTL1_TKTL2_TKT_1 "
     inkscape:connector-curvature="0"
     id="B_TKTL1_TKTL2_TKT_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.69710004"
     d="m 965.6,172.01855 25.6,19.2 0,0 m -26.5,0.5 25.6,-19.2"
     class="st31"
     inkscape:label="TKTL1_TKTL2_TKT_1 "
     inkscape:connector-curvature="0"
     id="R_TKTL1_TKTL2_TKT_1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text156"
     class="st15 st16"
     x="997.87823"
     y="172.36835">GA3P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text158"
     class="st15 st16"
     x="998.20343"
     y="200.00905">F6P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text160"
     class="st15 st16"
     x="924.83331"
     y="199.35765">Xil5P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text162"
     class="st15 st16"
     x="899.55011"
     y="119.60376">Sed1,7BP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text164"
     class="st17 st18"
     x="862.2395"
     y="101.52756">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text166"
     class="st17 st18"
     x="878.388"
     y="101.37626">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 974.2,113.01855 c -7.1,2.6 -7.1,2.6 -7.1,2.6 l 7.3,1.8 -2,-2 1.8,-2.4 z"
     class="st32"
     inkscape:label="forward ALDOC_ALDOB_ALDOA_1 "
     inkscape:connector-curvature="0"
     id="F_ALDOC_ALDOB_ALDOA_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.84440005"
     d="m 988.6,115.41855 0,13.6 m -16.1,-13.5 32.6,0"
     class="st13"
     inkscape:connector-curvature="0"
     id="R_ALDOC_ALDOB_ALDOA_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.03660011"
     d="m 990.5,127.81855 c -1.7,5.4 -1.7,5.4 -1.7,5.4 l -2.2,-5.2 2,1.3 1.9,-1.5 z m 13.7,-14.3 c 6.9,2.2 6.9,2.2 6.9,2.2 l -6.9,2.2 1.7,-2.2 -1.7,-2.2 z"
     class="st33"
     inkscape:label="B ALDOC_ALDOB_ALDOA_1"
     inkscape:connector-curvature="0"
     id="B_ALDOC_ALDOB_ALDOA_1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text171"
     class="st15 st16"
     x="1014.1517"
     y="119.70486">Ery4P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text173"
     class="st15 st16"
     x="968.1048"
     y="145.78055">DHAP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text175"
     class="st15 st16"
     x="771.2854"
     y="226.97975">PRPP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text177"
     class="st17 st18"
     x="826.94464"
     y="243.12035">Gly</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text179"
     class="st17 st18"
     x="913.92413"
     y="243.37524">2 10-forTHF</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text181"
     class="st17 st18"
     x="857.57452"
     y="209.29074">2 THF</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text183"
     class="st17 st18"
     x="884.82159"
     y="209.54565">PPi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text185"
     class="st17 st18"
     x="901.06671"
     y="208.81564">4 ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text187"
     class="st17 st18"
     x="836.94171"
     y="209.48065">Fum</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text189"
     class="st15 st16"
     x="1001.889"
     y="227.94115">IMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text191"
     class="st17 st18"
     x="802.77081"
     y="243.09105">2 Gln</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text193"
     class="st17 st18"
     x="812.37921"
     y="209.35135">2 Glu</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text195"
     class="st17 st18"
     x="890.34705"
     y="243.16335">4 ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text197"
     class="st17 st18"
     x="868.02661"
     y="242.86446">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text199"
     class="st17 st26"
     x="874.25714"
     y="244.86446">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text201"
     class="st17 st18"
     x="877.34601"
     y="242.86446">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text203"
     class="st17 st18"
     x="964.69855"
     y="243.09105">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text205"
     class="st17 st26"
     x="976.56384"
     y="245.09105">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text207"
     class="st15 st16"
     x="1268.7963"
     y="274.35965">GDP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text209"
     class="st17 st18"
     x="1227.5297"
     y="295.81955">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text211"
     class="st17 st18"
     x="1245.308"
     y="295.39575">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text213"
     class="st17 st18"
     x="588.70343"
     y="538.1087">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text215"
     class="st17 st18"
     x="593.98761"
     y="501.60864">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text217"
     class="st17 st18"
     x="617.54913"
     y="538.3645">CoA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text219"
     class="st15 st16"
     x="663.85974"
     y="522.77277">AcCoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text221"
     class="st17 st18"
     x="631.93585"
     y="501.30786">OAA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text223"
     class="st15 st16"
     x="1047.556"
     y="522.03638">ippPP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text225"
     class="st15 st16"
     x="1123.9662"
     y="522.45044">fPP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text227"
     class="st15 st16"
     x="1293.7357"
     y="521.42017">Chol</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text229"
     class="st17 st18"
     x="715.52472"
     y="482.08426">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text231"
     class="st17 st18"
     x="735.80505"
     y="481.85086">HCO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text233"
     class="st17 st26"
     x="753.9007"
     y="483.85086">3</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text235"
     class="st17 st26"
     x="756.98865"
     y="476.35086">-</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text237"
     class="st17 st18"
     x="763.59314"
     y="481.23465">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text239"
     class="st17 st18"
     x="727.01691"
     y="449.72195">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text241"
     class="st17 st18"
     x="766.38605"
     y="449.12424">Pi</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text243"
     class="st15 st16"
     x="790.05304"
     y="468.83524">MalCoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text245"
     class="st17 st18"
     x="882.31775"
     y="413.45636">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text247"
     class="st17 st26"
     x="894.18292"
     y="415.45636">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text249"
     class="st15 st16"
     x="914.74835"
     y="432.96216">AcAcACP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text251"
     class="st17 st18"
     x="999.9397"
     y="447.29025">14NADPH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text253"
     class="st17 st18"
     x="1008.5541"
     y="412.44064">14NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text255"
     class="st17 st18"
     x="1071.347"
     y="412.67795">6 H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text257"
     class="st17 st26"
     x="1084.9066"
     y="414.67795">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text259"
     class="st17 st18"
     x="1087.9945"
     y="412.67795">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text261"
     class="st17 st18"
     x="1045.3734"
     y="412.36255">6 CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text263"
     class="st17 st26"
     x="1064.5677"
     y="414.36255">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text265"
     class="st15 st16"
     x="1105.4926"
     y="433.46994">Palm</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text267"
     class="st17 st18"
     x="949.78149"
     y="447.81464">6 MalACP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text269"
     class="st17 st18"
     x="982.41632"
     y="413.04025">7 ACP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text271"
     class="st17 st18"
     x="857.53351"
     y="449.55005">CoA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text273"
     class="st15 st16"
     x="887.2757"
     y="468.92606">MalACP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text275"
     class="st17 st18"
     x="848.5813"
     y="482.83524">ACP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text277"
     class="st17 st18"
     x="756.85382"
     y="411.64575">CoA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text279"
     class="st15 st16"
     x="791.37335"
     y="434.89474">AcACP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text281"
     class="st17 st18"
     x="747.01202"
     y="447.85574">ACP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.59029996"
     d="m 761,430.21855 c -5.4,1.2 -4.9,10.4 -4.9,10.4 m 4.5,-10.5 c 5.3,-1 4,-9.8 4,-9.8 m -64.6,89 0.4,-79.2 79.6,0"
     class="st34"
     inkscape:connector-curvature="0"
     id="R_FASN_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.72870004"
     d="m 855.7,430.31855 c 6.2,-0.4 7.2,-8.3 7.2,-8.3 m 28,33.5 -10,-25.7 m -45.2,0.4 68.9,-0.3 m -20.5,0.2 c 6.1,-0.6 6.4,-8.5 6.4,-8.5"
     class="st35"
     inkscape:connector-curvature="0"
     id="R_AcAcACPSynthesis" /><text
     style="font-size:10px;font-family:Calibri"
     id="text285"
     class="st17 st18"
     x="855.91821"
     y="414.73166">ACP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.77409995"
     d="m 729.6,464.51855 c -6,1.1 -5.5,9.1 -5.5,9.1 m 5.8,-9.3 c 5.9,-0.9 4.4,-8.8 4.4,-8.8 m 30.6,8.8 c 5.9,-0.9 4.4,-8.8 4.4,-8.8 m -59.2,8.5 25.7,0.6 44.2,-0.3 m -28,0.2 c -6,1.1 -5.5,9.1 -5.5,9.1 m 25.5,-9.1 c -6,1.1 -5.5,9.1 -5.5,9.1 m -56.2,37.3 0,-47.7"
     class="st36"
     inkscape:label="ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2"
     inkscape:connector-curvature="0"
     id="R_ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.23090005"
     d="m 1428,1116.5186 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z m 57.5,-14.1 c 1.8,-5.9 1.8,-5.9 1.8,-5.9 l 2.5,5.6 -2.3,-1.3 -2,1.6 z"
     class="st37"
     inkscape:connector-curvature="0"
     id="F_ALDH3B1_ALDH3A1_ALDH3B2_ALDH1A3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1499.2,1027.2186 -73.8,0 0,0 m 21.8,0 c -5.9,-1.6 -4.4,-14.8 -4.4,-14.8 m 43.4,14.6 c 4.7,-3.6 3.8,-14.7 1.1,-14.6"
     class="st32"
     inkscape:connector-curvature="0"
     id="R_SLC25A3" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text290"
     class="st15 st16"
     x="1480.8578"
     y="1008.175">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text292"
     class="st15 st16"
     x="1501.9437"
     y="1029.9797">Pi</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text294"
     class="st15 st16"
     x="1438.8285"
     y="1005.4563">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text296"
     class="st15 st16"
     x="1401.4027"
     y="1030.7034">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.23090005"
     d="m 1425.9,1028.9186 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z m 14.4,-15.2 c 2.4,-5.7 2.4,-5.7 2.4,-5.7 l 2,5.8 -2.1,-1.5 -2.3,1.4 z"
     class="st37"
     inkscape:connector-curvature="0"
     id="F_SLC25A3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1502.9,1072.8186 c -24.6,0 -49.2,0 -73.8,0 m 21.8,0 c -3.5,-1 -4.2,-5.1 -4.5,-8.3 -0.2,-2 -0.1,-3.9 0.1,-5.9 m 43,14 c 0.4,-4.6 2.5,-9 2.7,-13.7 0,-0.4 -0.1,-1.1 -0.7,-1.1"
     class="st32"
     inkscape:connector-curvature="0"
     id="R_SLC25A5_SLC25A4_SLC25A6" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text300"
     class="st15 st16"
     x="1479.5199"
     y="1049.1731">ATP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text302"
     class="st15 st16"
     x="1511.3929"
     y="1077.179">ADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text304"
     class="st15 st16"
     x="1432.8539"
     y="1049.8508">ATP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text306"
     class="st15 st16"
     x="1391.6039"
     y="1077.1125">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.23090005"
     d="m 1429.5,1074.5186 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z m 61,-14.2 c 2.1,-5.8 2.1,-5.8 2.1,-5.8 l 2.2,5.7 -2.2,-1.4 -2.1,1.5 z"
     class="st37"
     inkscape:label="#F_SLC25A5_SLC25A4_SLC25A6"
     inkscape:connector-curvature="0"
     id="F_SLC25A5_SLC25A4_SLC25A6" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1501.4,1114.8186 -73.8,0 0,0 m 21.8,0 c -5.9,-1.4 -4.4,-13.5 -4.4,-13.5 m 41.7,-1 c 3.2,6.1 -5.5,14.6 -5.5,14.6"
     class="st32"
     inkscape:connector-curvature="0"
     id="R_ALDH3B1_ALDH3A1_ALDH3B2_ALDH1A3" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text310"
     class="st15 st38"
     x="1473.5541"
     y="1092.8215">GTP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text312"
     class="st15 st16"
     x="1509.8929"
     y="1117.5793">GDP</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text314"
     class="st15 st38"
     x="1428.8754"
     y="1092.8958">GTP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text316"
     class="st15 st16"
     x="1390.0355"
     y="1119.3235">GDP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.23090005"
     d="m 1500.2,1112.5186 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z m -57.8,-10.4 c 2.4,-5.7 2.4,-5.7 2.4,-5.7 l 2,5.8 -2.1,-1.5 -2.3,1.4 z"
     class="st37"
     inkscape:connector-curvature="0"
     id="B_ALDH3B1_ALDH3A1_ALDH3B2_ALDH1A3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1442.3,832.21855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
     class="st32"
     inkscape:label="forward AQP8 "
     inkscape:connector-curvature="0"
     id="F_AQP8" /><path
     style="fill:none;stroke:#000000;stroke-width:1.77520001"
     d="m 1493,830.41855 -50.4,0 0,0"
     class="st39"
     inkscape:label="AQP8 "
     inkscape:connector-curvature="0"
     id="R_AQP8" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1489,828.11855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
     class="st32"
     inkscape:transform-center-y="2.6134784"
     inkscape:transform-center-x="-0.38596577"
     inkscape:label="backward AQP8 "
     inkscape:connector-curvature="0"
     id="B_AQP8" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text322"
     class="st15 st16"
     x="1501.9828"
     y="834.84888">H</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text324"
     class="st15 st40"
     x="1512.0765"
     y="838.04907">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text326"
     class="st15 st16"
     x="1517.0179"
     y="834.84888">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text328"
     class="st15 st16"
     x="1405.2406"
     y="834.85181">H</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text330"
     class="st15 st40"
     x="1415.3344"
     y="838.052">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text332"
     class="st15 st16"
     x="1420.2758"
     y="834.85181">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text334"
     class="st15 st16"
     x="1501.2924"
     y="920.34888">O</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text336"
     class="st15 st40"
     x="1512.1127"
     y="923.54907">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text338"
     class="st15 st16"
     x="1414.5111"
     y="921.31366">O</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text340"
     class="st15 st40"
     x="1425.3314"
     y="924.51385">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text342"
     class="st15 st16"
     x="1500.6859"
     y="857.42798">CO</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text344"
     class="st15 st40"
     x="1519.8578"
     y="860.6272">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text346"
     class="st15 st16"
     x="1405.0785"
     y="858.29315">CO</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text348"
     class="st15 st40"
     x="1424.2504"
     y="861.49341">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text350"
     class="st15 st16"
     x="1500.932"
     y="879.84888">CoA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text352"
     class="st15 st16"
     x="1400.6957"
     y="879.69458">CoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1441.9,917.71855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
     class="st32"
     inkscape:label="TransportOxygen F"
     inkscape:connector-curvature="0"
     id="F_TransportOxygen" /><path
     style="fill:none;stroke:#000000;stroke-width:1.88160002"
     d="m 1497.8,915.91855 -56.7,0 0,0"
     class="st41"
     inkscape:label="TransportOxygen"
     inkscape:connector-curvature="0"
     id="R_TransportOxygen" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1440.8,854.71855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
     class="st32"
     inkscape:label="forward Transport_CO2 "
     inkscape:connector-curvature="0"
     id="F_Transport_CO2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.86150002"
     d="m 1493.5,852.91855 -55.5,0 0,0"
     class="st42"
     inkscape:label="Transport_CO2 "
     inkscape:connector-curvature="0"
     id="R_Transport_CO2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1489,850.31855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
     class="st32"
     inkscape:transform-center-y="2.6134784"
     inkscape:transform-center-x="-0.38596577"
     inkscape:label="backward Transport_CO2 "
     inkscape:connector-curvature="0"
     id="B_Transport_CO2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1440.8,877.21855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
     class="st32"
     inkscape:label="backward SLC25A16 "
     inkscape:connector-curvature="0"
     id="B_SLC25A16" /><path
     style="fill:none;stroke:#000000;stroke-width:1.79229999"
     d="m 1492.5,875.11855 -51.4,0 0,0"
     class="st43"
     inkscape:label="SLC25A16 "
     inkscape:connector-curvature="0"
     id="R_SLC25A16" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1490.5,872.71855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
     class="st32"
     inkscape:transform-center-y="2.6134784"
     inkscape:transform-center-x="-0.38596577"
     inkscape:label="forward SLC25A16 "
     inkscape:connector-curvature="0"
     id="F_SLC25A16" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text362"
     class="st15 st16"
     x="1501.2006"
     y="899.49829">NH</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text364"
     class="st15 st40"
     x="1521.8334"
     y="902.69849">3</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text366"
     class="st15 st16"
     x="1402.0922"
     y="899.6507">NH</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text368"
     class="st15 st40"
     x="1422.725"
     y="902.85089">3</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1439.3,896.71855 c -6.9,-2.1 -6.9,-2.1 -6.9,-2.1 l 6.9,-2.3 -1.7,2.2 1.7,2.2 z"
     class="st32"
     inkscape:label="forward HIBCH "
     inkscape:connector-curvature="0"
     id="F_HIBCH" /><path
     style="fill:none;stroke:#000000;stroke-width:1.86909997"
     d="m 1494.1,894.91855 -55.9,0 0,0"
     class="st44"
     inkscape:label="HIBCH "
     inkscape:connector-curvature="0"
     id="R_HIBCH" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1490.8,892.61855 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
     class="st32"
     inkscape:transform-center-y="2.6134784"
     inkscape:transform-center-x="-0.38596577"
     inkscape:label="backward HIBCH "
     inkscape:connector-curvature="0"
     id="B_HIBCH" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text373"
     class="st15 st16"
     x="183.5808"
     y="877.27655">AKG</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text375"
     class="st15 st16"
     x="284.44901"
     y="878.07635">AKG</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 275.8,872.81855 -60.2,-0.3 m 44.6,0.3 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -26.7,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7"
     class="st45"
     inkscape:connector-curvature="0"
     id="R_SLC25A10_3" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text378"
     class="st15 st38"
     x="225.0891"
     y="851.62427">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.35560012"
     d="m 233.9,861.71855 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 40.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st46"
     inkscape:connector-curvature="0"
     id="F_SLC25A10_3" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text381"
     class="st15 st16"
     x="541.16345"
     y="867.11346">OAA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text383"
     class="st15 st16"
     x="444.4646"
     y="817.42017">AcCoA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text385"
     class="st15 st16"
     x="552.0061"
     y="801.70825">Cit</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text387"
     class="st15 st16"
     x="584.02271"
     y="750.14575">Isocit</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text389"
     class="st15 st16"
     x="720.78931"
     y="750.92017">AKG</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text391"
     class="st17 st18"
     x="618.72882"
     y="720.4563">NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text393"
     class="st17 st18"
     x="647.54321"
     y="718.54126">NADPH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text395"
     class="st17 st18"
     x="620.67413"
     y="781.10181">NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text397"
     class="st17 st18"
     x="649.48175"
     y="783.26978">NADH</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text399"
     class="st15 st16"
     x="762.93884"
     y="808.12225">SuCoA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text401"
     class="st15 st16"
     x="768.40649"
     y="883.388">Succ</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text403"
     class="st15 st16"
     x="702.18781"
     y="941.1272">Fum</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text405"
     class="st15 st16"
     x="578.7005"
     y="921.75116">Mal</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.04839993"
     d="m 566.7,779.01855 c -1.3,6.1 -1.3,6.1 -1.3,6.1 l 4.5,-4.4 -2.3,0.5 -0.9,-2.2 z"
     class="st47"
     inkscape:label="backward aconitase"
     inkscape:connector-curvature="0"
     id="B_ACO2_ACO1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.12699997"
     d="m 566.9,782.01855 c 4.6,-9.3 11.1,-17.4 19,-23.8"
     class="st48"
     inkscape:connector-curvature="0"
     id="R_ACO2_ACO1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.04839993"
     d="m 585.4,760.31855 c 3.7,-5 3.7,-5 3.7,-5 l -5.8,2.2 2.3,0.5 -0.2,2.3 z"
     class="st47"
     inkscape:label="forward aconitase"
     inkscape:connector-curvature="0"
     id="F_ACO2_ACO1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.04839993"
     d="m 613.2,930.01855 c -5.9,-2.2 -5.9,-2.2 -5.9,-2.2 l 3.7,5 -0.1,-2.3 2.3,-0.5 z"
     class="st47"
     inkscape:label="forward fumarase"
     inkscape:connector-curvature="0"
     id="F_FH_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.53830004"
     d="m 750,753.21855 c 11.4,9.5 20.7,21.6 27.4,35.6 m 7.1,-13.7 c -5.5,3.4 -13.1,1.9 -17.3,-3.3 -4.2,-5.2 -3.5,-12.4 1.5,-16.3"
     class="st49"
     inkscape:label="DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL"
     inkscape:connector-curvature="0"
     id="R_DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL" /><text
     style="font-size:10px;font-family:Calibri"
     id="text412"
     class="st17 st18"
     x="770.49744"
     y="758.63306">NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text414"
     class="st17 st18"
     x="788.89093"
     y="758.63306">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text416"
     class="st17 st18"
     x="793.8714"
     y="758.63306">CoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.4921"
     d="m 804.5,854.61855 c -5.7,0.4 -11.1,-2.1 -14.1,-6.4 -3,-4.3 -3,-9.8 -0.1,-14.1 2.9,-4.3 8.3,-6.9 14,-6.5 m -18.4,38.9 c 3.7,-17.5 3.4,-35.7 -0.7,-53.3"
     class="st50"
     inkscape:connector-curvature="0"
     id="R_KANK1_SUCLA2_SUCLG1_SUCLG2_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text419"
     class="st17 st18"
     x="812.39685"
     y="828.55005">GDP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text421"
     class="st17 st18"
     x="830.02374"
     y="828.55005">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text423"
     class="st17 st18"
     x="835.00421"
     y="828.55005">Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text425"
     class="st17 st18"
     x="814.06671"
     y="857.71606">GTP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text427"
     class="st17 st18"
     x="830.36554"
     y="857.71606">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text429"
     class="st17 st18"
     x="835.34601"
     y="857.71606">CoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.41170001"
     d="m 762.8,933.01855 c -4.7,-2.1 -7.7,-6.5 -7.5,-11.2 0.2,-4.7 3.4,-8.9 8.2,-10.5 4.8,-1.7 10.3,-0.5 14,2.9 m -2.6,-22 c -9,15.5 -21.4,28.8 -36.4,39.2"
     class="st51"
     inkscape:connector-curvature="0"
     id="R_SDHA_SDHB_SDHC_SDHD" /><text
     style="font-size:10px;font-family:Calibri"
     id="text432"
     class="st17 st18"
     x="784.63501"
     y="920.19165">FAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text434"
     class="st17 st18"
     x="764.34894"
     y="943.30975">FADH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text436"
     class="st17 st26"
     x="786.55115"
     y="945.30975">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.37870002"
     d="m 578.6,907.21855 c -8.4,-8.4 -15,-18.8 -19.3,-30.4 m -8,12 c 3.1,-2 7.4,-2.3 10.9,-0.8 3.6,1.6 5.8,4.7 5.8,8.2 0,3.4 -2.2,6.6 -5.8,8"
     class="st52"
     inkscape:connector-curvature="0"
     id="R_MDH2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text439"
     class="st17 st18"
     x="537.08234"
     y="912.11646">NAD</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text441"
     class="st15 st16"
     x="451.4158"
     y="732.70825">Pyr</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.24370003"
     d="m 464.2,739.41855 0.2,56.6 m -0.5,-21.6 c 1.5,5.9 13.6,4.1 13.6,4.1 m -13.3,-14.1 c 1.5,5.9 13.4,4.1 13.4,4.1 m -13.1,1.8 c -1.6,-6 -12.9,-5.2 -12.9,-5.2 m 12.4,-12.6 c -1.5,-6 -12.4,-5.2 -12.4,-5.2 m 12.7,6.1 c 1.5,5.9 13.2,4.1 13.2,4.1"
     class="st53"
     inkscape:label="DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB "
     inkscape:connector-curvature="0"
     id="R_DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB" /><text
     style="font-size:10px;font-family:Calibri"
     id="text444"
     class="st17 st18"
     x="567.64972"
     y="846.81366">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text446"
     class="st17 st26"
     x="573.88025"
     y="848.81366">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text448"
     class="st17 st18"
     x="576.96814"
     y="846.81366">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text450"
     class="st17 st18"
     x="569.51593"
     y="825.74438">CoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text452"
     class="st17 st18"
     x="695.72681"
     y="780.76196">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text454"
     class="st17 st26"
     x="707.5921"
     y="782.76196">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text456"
     class="st17 st18"
     x="696.48865"
     y="719.4046">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text458"
     class="st17 st26"
     x="708.35382"
     y="721.4046">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.04839993"
     d="m 664.2,952.91855 c 5.8,2.2 5.8,2.2 5.8,2.2 l -3.7,-5 0.1,2.3 -2.2,0.5 z m 27.9,-11.2 c 4.9,-3.8 4.9,-3.8 4.9,-3.8 l -6.2,0.6 2,1.1 -0.7,2.1 z"
     class="st47"
     inkscape:connector-curvature="0"
     id="B_FH_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.84920001"
     d="m 666.6,952.31855 -16.4,-9.8 m 41.7,-2.8 c -33.5,7.3 -52.1,2.6 -79.1,-8.8"
     class="st54"
     inkscape:connector-curvature="0"
     id="R_FH_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text462"
     class="st17 st18"
     x="672.46021"
     y="961.96796">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text464"
     class="st17 st26"
     x="678.69073"
     y="963.96796">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text466"
     class="st17 st18"
     x="681.7796"
     y="961.96796">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.81599998"
     d="m 561.8,902.51855 c -4,4 -4,4 -4,4 l 5.5,-0.9 -1.9,-1 0.4,-2.1 z m 13.6,3.9 c 6,1.7 6,1.7 6,1.7 l -4.1,-4.7 0.3,2.3 -2.2,0.7 z"
     class="st55"
     inkscape:connector-curvature="0"
     id="B_MDH2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81599998"
     d="m 739.7,928.21855 c -4.1,4.7 -4.1,4.7 -4.1,4.7 l 6,-1.7 -2.2,-0.7 0.3,-2.3 z m 21.4,5.7 c 5.3,1.4 5.3,1.4 5.3,1.4 l -3.6,-4.5 0.3,2.3 -2,0.8 z"
     class="st55"
     inkscape:connector-curvature="0"
     id="F_SDHA_SDHB_SDHC_SDHD" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81599998"
     d="m 774.9,896.21855 c 1.3,-6.1 1.3,-6.1 1.3,-6.1 l -4.4,4.4 2.3,-0.5 0.8,2.2 z m 1.2,19.4 c 6.1,1.1 6.1,1.1 6.1,1.1 l -4.5,-4.3 0.5,2.2 -2.1,1 z"
     class="st55"
     inkscape:connector-curvature="0"
     id="B_SDHA_SDHB_SDHC_SDHD" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81599998"
     d="m 785.2,863.01855 c 0.1,6.2 0.1,6.2 0.1,6.2 l 3.3,-5.3 -2.1,1 -1.3,-1.9 z m 18.8,-7 c 6.1,-1.5 6.1,-1.5 6.1,-1.5 l -5.9,-2 1.4,1.8 -1.6,1.7 z"
     class="st55"
     inkscape:connector-curvature="0"
     id="F_KANK1_SUCLA2_SUCLG1_SUCLG2_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81599998"
     d="m 788.1,817.61855 c -3.6,-5.1 -3.6,-5.1 -3.6,-5.1 l 0.2,6.2 1.2,-2 2.2,0.9 z m 14.8,11.6 c 6,-1.6 6,-1.6 6,-1.6 l -5.9,-1.9 1.5,1.8 -1.6,1.7 z"
     class="st55"
     inkscape:connector-curvature="0"
     id="B_KANK1_SUCLA2_SUCLG1_SUCLG2_1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text473"
     class="st15 st16"
     x="177.26639"
     y="802.27655">Fum</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text475"
     class="st15 st16"
     x="283.87378"
     y="800.91235">Fum</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 275.8,797.81855 -60.2,-0.3 m 44.6,0.2 c 5.9,-1.6 4.4,-15.3 4.4,-15.3 m -31.3,15.6 c -6.4,-4.5 -7.8,-15.5 -5,-15.5"
     class="st45"
     inkscape:connector-curvature="0"
     id="R_SLC25A10_4" /><path
     style="fill:none;stroke:#000000;stroke-width:2.0158999"
     d="m 229.9,783.11855 c -2.1,-4.9 -2.1,-4.9 -2.1,-4.9 l -2,5 2.1,-1.3 2,1.2 z m 44.1,16.7 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st56"
     inkscape:label=" B SLC25A10_4"
     inkscape:connector-curvature="0"
     id="B_SLC25A10_4" /><path
     style="fill:none;stroke:#000000;stroke-width:2.00889993"
     d="m 267,783.11855 c -1.6,-5.3 -1.6,-5.3 -1.6,-5.3 l -2.3,5.1 2,-1.2 1.9,1.4 z m -50.7,12.4 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
     class="st57"
     inkscape:label="F SLC25A10_4"
     inkscape:connector-curvature="0"
     id="F_SLC25A10_4" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text480"
     class="st15 st38"
     x="260.33328"
     y="777.0979">Pi</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text482"
     class="st15 st38"
     x="222.5813"
     y="777.03638">Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text484"
     class="st17 st18"
     x="482.52859"
     y="702.16626">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text486"
     class="st17 st18"
     x="444.9617"
     y="668.1311">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text488"
     class="st15 st16"
     x="465.6225"
     y="1131.1801">NAD</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text490"
     class="st15 st16"
     x="499.44772"
     y="1131.5101">QH</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text492"
     class="st15 st40"
     x="520.51807"
     y="1134.7103">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text494"
     class="st15 st16"
     x="396.8374"
     y="1133.059">5 H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.26660001"
     d="m 380.1998,1138.2711 0,17.7 133.5,0 0,-17.7 m -104.6,-1.6 0,18.7 m 26.7,-18.1 0,18.2 m 49,0 0,-17 m -13,17 0,28.6"
     class="st58"
     inkscape:connector-curvature="0"
     id="R_Complex1ROS"
     inkscape:label="#R_Complex1ROS" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text505"
     class="st15 st16"
     x="580.42444"
     y="1130.2744">2 Cytc-ox</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text507"
     class="st15 st16"
     x="738.55164"
     y="1130.0198">2 Cytc-red</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text509"
     class="st15 st16"
     x="834.18854"
     y="1130.3486">Q</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text511"
     class="st15 st16"
     x="667.68347"
     y="1131.8838">2H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text513"
     class="st15 st16"
     x="702.59131"
     y="1130.5463">QH</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text515"
     class="st15 st40"
     x="723.66162"
     y="1135.3677">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.29487193"
     d="m 643.71124,1137.3649 0,18.3 195.54681,0 0,-18.3 m -159.78839,-0.3 0,18.2 m 41.6057,-17.5 0,17.4 m 65.782,0.1 0,-15.3 m -27.54973,15.6 0,24.5"
     class="st60"
     inkscape:connector-curvature="0"
     id="R_Complex3" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text518"
     class="st15 st16"
     x="746.68384"
     y="1199.0907">4 H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text520"
     class="st15 st16"
     x="888.39905"
     y="1132.1252">4 Cytc-red</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text522"
     class="st15 st16"
     x="1039.7281"
     y="1131.0266">4 Cytc-ox</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text524"
     class="st15 st16"
     x="1123.9191"
     y="1132.1672">2H</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text526"
     class="st15 st40"
     x="1145.7395"
     y="1135.3684">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text528"
     class="st15 st16"
     x="1150.6809"
     y="1132.1672">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text530"
     class="st15 st16"
     x="981.8186"
     y="1132.9836">8H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text532"
     class="st15 st16"
     x="1011.5463"
     y="1132.6321">O</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text534"
     class="st15 st40"
     x="1022.3666"
     y="1135.8323">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.18280005"
     d="m 951.7,1138.8186 0,16.2 192.2,0 0,-16.2 m -152.2,-0.5 0,16.2 m 26.6,-15.7 0,15.8 m 53.3,-0.1 0,-13.8 m -23.8,13.8 0,25.4"
     class="st61"
     inkscape:connector-curvature="0"
     id="R_Complex4" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text537"
     class="st15 st16"
     x="1035.0892"
     y="1196.552">4 H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text539"
     class="st15 st16"
     x="890.96515"
     y="866.2962">CO</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text541"
     class="st15 st40"
     x="910.13702"
     y="869.4964">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text543"
     class="st15 st16"
     x="962.79913"
     y="866.07635">HCO</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text545"
     class="st15 st40"
     x="992.0647"
     y="869.27655">3</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text547"
     class="st15 st40"
     x="997.0061"
     y="857.27655">-</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.06990004"
     d="m 929.8,861.11855 c -6.3,1.9 -5.8,15.6 -5.8,15.6 m 12.8,-15.5 c 6.4,1.4 4.8,12.8 4.8,12.8 m 11,-13 -36,-0.3"
     class="st62"
     inkscape:connector-curvature="0"
     id="R_CA5B_CA5A" /><text
     style="font-size:10px;font-family:Calibri"
     id="text550"
     class="st17 st18"
     x="938.54132"
     y="886.07739">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text552"
     class="st17 st18"
     x="913.19171"
     y="885.12616">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text554"
     class="st17 st26"
     x="919.42224"
     y="887.12616">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text556"
     class="st17 st18"
     x="922.51105"
     y="885.12616">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1170.1,1230.7186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="Glucose_DM_COOP b"
     inkscape:connector-curvature="0"
     id="B_Glucose_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1172.1,1229.4186 0.7,48.1"
     class="st14"
     inkscape:label="Glucose_DM_COOP"
     inkscape:connector-curvature="0"
     id="R_Glucose_DM_COOP" /><a
     transform="translate(1273.3622,1205.6018)"
     xlink:href="http://www.genome.jp/dbget-bin/www_bget?cpd:C00031"
     id="a14384-0"><text
       style="font-size:16px;font-family:Calibri-Bold"
       id="text561"
       class="st15 st16"
       transform="translate(-116.0982,12.7041)">Glc</text>
</a><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 501.1,1274.6186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
     class="st63"
     inkscape:label="Ex_SC_H2O f"
     inkscape:connector-curvature="0"
     id="F_Ex_SC_H2O" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 503.2,1227.4186 0,47.6"
     class="st63"
     inkscape:label="Ex_SC_H2O"
     inkscape:connector-curvature="0"
     id="R_Ex_SC_H2O" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text565"
     class="st15 st16"
     x="488.92899"
     y="1219.1184">H</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text567"
     class="st15 st40"
     x="499.02267"
     y="1222.3176">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text569"
     class="st15 st16"
     x="503.96512"
     y="1219.1184">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.67510009"
     d="m 561.7,1232.4186 -2.2,-7.1 -2.2,7.1 2.2,-1.8 2.2,1.8 z"
     class="st64"
     inkscape:label="Ex_O2 b"
     inkscape:connector-curvature="0"
     id="B_Ex_O2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.67510009"
     d="m 559.6,1278.6186 0,-46.6"
     class="st64"
     inkscape:label="Ex_O2"
     inkscape:connector-curvature="0"
     id="R_Ex_O2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text573"
     class="st15 st16"
     x="553.19659"
     y="1218.1301">O</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text575"
     class="st15 st40"
     x="564.01691"
     y="1221.3303">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1236.1431,1273.3107 -2.2,7.3 -2.2,-7.3 2.2,1.8 2.2,-1.8 z"
     class="st14"
     inkscape:label="Glutamine_DM_COOP f"
     inkscape:connector-curvature="0"
     id="F_Glutamine_DM_COOP" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text579"
     class="st15 st16"
     x="1219.5931"
     y="1218.3059">Gln</text>
<path
     style="fill:none;stroke:#000000;stroke-width:3.16359997"
     d="m 643.8,1274.6186 2.2,6.9 2.2,-6.9 -2.2,1.7 -2.2,-1.7 z"
     class="st65"
     inkscape:label="forward Ex_NH3 "
     inkscape:connector-curvature="0"
     id="F_Ex_NH3" /><path
     style="fill:none;stroke:#000000;stroke-width:3.36989999"
     d="m 645.9,1223.3186 0,51.7"
     class="st66"
     inkscape:label="Ex_NH3 "
     inkscape:connector-curvature="0"
     id="R_Ex_NH3" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text583"
     class="st15 st16"
     x="635.18091"
     y="1219.1711">NH</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text585"
     class="st15 st40"
     x="655.81384"
     y="1222.3713">3</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 841.2,1232.3186 2.2,-7.3 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="DM_Folate f"
     inkscape:connector-curvature="0"
     id="F_DM_Folate" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 843.5,1276.7186 -0.3,-48.1"
     class="st14"
     inkscape:label="DM_Folate"
     inkscape:connector-curvature="0"
     id="R_DM_Folate" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text589"
     class="st15 st16"
     x="821.54034"
     y="1218.8098">Folate</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.31469989"
     d="m 689.2,1223.4186 0,56.6"
     class="st67"
     inkscape:label="DM_Urea"
     inkscape:connector-curvature="0"
     id="R_DM_Urea" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text592"
     class="st15 st16"
     x="672.34991"
     y="1218.9426">Urea</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22029996"
     d="m 890.5,1223.6186 0.3,50.4"
     class="st68"
     inkscape:label="DM_putrescine"
     inkscape:connector-curvature="0"
     id="R_DM_putrescine" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text595"
     class="st15 st16"
     x="873.35284"
     y="1219.4836">Putr</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text597"
     class="st15 st16"
     x="1115.0238"
     y="1218.8967">Lact</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 1141.3465,1230.8815 -2.2,-7.7 -2.2,7.7 2.2,-1.9 2.2,1.9 z"
     class="st69"
     inkscape:label="LactateL_DM_COOP b"
     inkscape:connector-curvature="0"
     id="B_LactateL_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 501.1,1232.3186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="Ex_SC_H2O b"
     inkscape:connector-curvature="0"
     id="B_Ex_SC_H2O" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 532.3,1274.6186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
     class="st63"
     inkscape:label="forward Ex_SC_H "
     inkscape:connector-curvature="0"
     id="F_Ex_SC_H" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 534.4,1227.4186 0,47.6"
     class="st63"
     inkscape:label="Ex_SC_Hs"
     inkscape:connector-curvature="0"
     id="R_Ex_SC_Hs" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text604"
     class="st15 st16"
     x="529.56775"
     y="1219.1184">H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 532.3,1232.3186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="backward Ex_SC_H "
     inkscape:connector-curvature="0"
     id="B_Ex_SC_H" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 687.5,1275.3186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
     class="st63"
     inkscape:label="DM_Urea f"
     inkscape:connector-curvature="0"
     id="F_DM_Urea" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 888.7,1273.2186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
     class="st63"
     inkscape:label="DM_putrescine f"
     inkscape:connector-curvature="0"
     id="F_DM_putrescine" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text609"
     class="st15 st16"
     x="1258.4867"
     y="1218.8098">Glu</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 1267.4,1273.3186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
     class="st69"
     inkscape:label="Glutamate_DM_COOP f"
     inkscape:connector-curvature="0"
     id="F_Glutamate_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 1270,1225.4186 0,50.5"
     class="st69"
     inkscape:label="Glutamate_DM_COOP"
     inkscape:connector-curvature="0"
     id="R_Glutamate_DM_COOP" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text613"
     class="st15 st16"
     x="1294.558"
     y="1219.0598">Arg</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 1305.8,1231.5186 2.2,1.8 -2.2,-7.2 -2.2,7.2 2.2,-1.8 z"
     class="st63"
     inkscape:label="Arginine_DM_COOP f"
     inkscape:connector-curvature="0"
     id="F_Arginine_DM_COOP" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text616"
     class="st15 st16"
     x="577.40161"
     y="1218.1838">CO</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text618"
     class="st15 st40"
     x="598.57355"
     y="1221.384">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 590,1229.9186 0,47.6"
     class="st63"
     inkscape:label="DM_CO2c"
     inkscape:connector-curvature="0"
     id="R_DM_CO2c" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text622"
     class="st15 st16"
     x="615.26984"
     y="1219.7141">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 620.5,1233.9186 0,47.6"
     class="st63"
     inkscape:label="Ex_SC_Pi "
     inkscape:connector-curvature="0"
     id="R_Ex_SC_Pi" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 620.6,1232.5186 2.2,1.8 -2.2,-7.2 -2.2,7.2 2.2,-1.8 z"
     class="st63"
     inkscape:label="Ex_SC_Pi b"
     inkscape:connector-curvature="0"
     id="B_Ex_SC_Pi" /><path
     style="fill:none;stroke:#000000;stroke-width:1.96669996"
     d="m 587.5,1271.4186 1.9,6.8 1.9,-6.8 -1.9,1.7 -1.9,-1.7 z"
     class="st70"
     inkscape:label="FORWARD DM_CO2c"
     inkscape:connector-curvature="0"
     id="F_DM_CO2c" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 618.6,1275.0186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
     class="st69"
     inkscape:label="Ex_SC_Pi f"
     inkscape:connector-curvature="0"
     id="F_Ex_SC_Pi" /><path
     style="fill:none;stroke:#000000;stroke-width:2.13409996"
     d="m 927.4,1281.5186 -0.8,-56.3"
     class="st71"
     inkscape:label="DM_guanidinoacetatec"
     inkscape:connector-curvature="0"
     id="R_DM_guanidinoacetatec" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 927.19047,1278.0186 -2.3,-1.7 2.4,7.2 2,-7.3 -2.1,1.8 z"
     class="st63"
     inkscape:label="DM_guanidinoacetatec f"
     inkscape:connector-curvature="0"
     id="F_DM_guanidinoacetatec" /><text
     style="font-size:15.99923611px;font-family:Calibri-Bold"
     id="text630"
     class="st15 st16"
     transform="matrix(0.99984771,-0.01745156,0.01745156,0.99984771,0,0)"
     x="896.45245"
     y="1235.1273">GA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text632"
     class="st17 st18"
     x="813.1839"
     y="294.34796">Asp</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text634"
     class="st17 st18"
     x="847.99152"
     y="294.67303">2 ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text636"
     class="st17 st18"
     x="838.64294"
     y="261.41425">QH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text638"
     class="st17 st26"
     x="851.60181"
     y="263.41425">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text640"
     class="st17 st18"
     x="859.31573"
     y="261.81076">2 ADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text642"
     class="st15 st16"
     x="950.24341"
     y="283.13986">UMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text644"
     class="st17 st18"
     x="792.67413"
     y="295.08524">Gln</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text646"
     class="st17 st18"
     x="800.29321"
     y="261.82446">Glu</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text648"
     class="st17 st18"
     x="886.02863"
     y="294.47684">HCO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text650"
     class="st17 st26"
     x="904.12433"
     y="296.47684">3</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text652"
     class="st17 st26"
     x="907.2132"
     y="288.97684">-</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text654"
     class="st17 st18"
     x="835.15265"
     y="294.92795">Q</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text656"
     class="st17 st18"
     x="875.8938"
     y="294.94363">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text658"
     class="st17 st18"
     x="906.9231"
     y="262.21405">PPi</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text660"
     class="st15 st16"
     x="953.64874"
     y="337.59396">UDP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text662"
     class="st17 st18"
     x="995.4729"
     y="301.37915">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text664"
     class="st17 st18"
     x="985.13312"
     y="312.31955">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.5819"
     d="m 937.8,332.81855 c -4.7,-0.3 -6.5,-11.7 -6.5,-11.7 m 21.4,11.5 -31.2,0.2"
     class="st72"
     inkscape:label="RRM2B_TXN_RRM1_RRM2_1"
     inkscape:connector-curvature="0"
     id="R_RRM2B_TXN_RRM1_RRM2_1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text667"
     class="st15 st16"
     x="872.57452"
     y="337.33325">dUDP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text669"
     class="st17 st18"
     x="920.89093"
     y="314.44846">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text671"
     class="st17 st26"
     x="927.1214"
     y="316.44846">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text673"
     class="st17 st18"
     x="930.21021"
     y="314.44846">O</text>
<text
     style="font-size:16.00037575px;font-family:Calibri-Bold"
     id="text675"
     class="st15 st16"
     transform="matrix(0.99997657,-0.0068447,0.0068447,0.99997657,0,0)"
     x="779.65546"
     y="343.09702">dUMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text677"
     class="st17 st18"
     transform="matrix(0.99990048,0.01410788,-0.01410788,0.99990048,0,0)"
     x="852.72308"
     y="304.24103">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text679"
     class="st17 st18"
     transform="matrix(0.9998951,-0.01448404,0.01448404,0.9998951,0,0)"
     x="827.13593"
     y="328.46188">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text681"
     class="st17 st18"
     x="923.82745"
     y="262.21405">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text683"
     class="st17 st26"
     x="935.69275"
     y="264.21405">2</text>
<text
     style="font-size:16.0006218px;font-family:Calibri-Bold"
     id="text685"
     class="st15 st16"
     transform="matrix(0.99976114,-0.02185571,0.02185571,0.99976114,0,0)"
     x="673.61633"
     y="353.25659">dTMP</text>
<text
     style="font-size:10.00026512px;font-family:Calibri"
     id="text687"
     class="st17 st18"
     transform="matrix(0.99997352,-0.00727731,0.00727731,0.99997352,0,0)"
     x="748.1861"
     y="319.31909">meTHF</text>
<text
     style="font-size:10.00010777px;font-family:Calibri"
     id="text689"
     class="st17 st18"
     transform="matrix(0.99998921,0.00464547,-0.00464547,0.99998921,0,0)"
     x="731.41992"
     y="310.3287">DHF</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text691"
     class="st15 st16"
     x="1025.2386"
     y="337.24924">UTP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text693"
     class="st15 st16"
     x="1113.8793"
     y="337.43964">CTP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text695"
     class="st17 st18"
     x="1079.4359"
     y="317.43384">ADP+Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text697"
     class="st17 st18"
     x="1039.0609"
     y="317.67896">ATP+NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text699"
     class="st17 st26"
     x="1071.7709"
     y="319.67896">3</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text701"
     class="st17 st18"
     x="1163.5892"
     y="316.63016">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text703"
     class="st17 st18"
     x="1144.7562"
     y="317.36545">ADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text705"
     class="st15 st16"
     x="1185.2777"
     y="337.33524">CDP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1157.5,324.71855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m -7,5.6 c -7.4,1.9 -7.4,1.9 -7.4,1.9 l 7.2,2.4 -1.8,-2.2 2,-2.1 z"
     class="st73"
     inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4"
     inkscape:connector-curvature="0"
     id="B_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1174.1,335.71855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -3.6,-10.9 c -1.1,-5.1 -1.1,-5.1 -1.1,-5.1 l -1.7,5 1.5,-1.2 1.3,1.3 z"
     class="st22"
     inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4"
     inkscape:connector-curvature="0"
     id="F_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text709"
     class="st15 st16"
     x="1258.7123"
     y="337.35764">CMP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.43479991"
     d="m 1198.8,339.01855 -0.1,22.4 m -0.1,-17.5 c -0.2,5.3 -9.5,7.3 -9.5,7.3"
     class="st74"
     inkscape:connector-curvature="0"
     id="R_RRM2B_TXN_RRM1_RRM2_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text712"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="1168.255"
     y="353.44818">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text714"
     class="st17 st26"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="1174.4854"
     y="355.44815">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text716"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="1177.5743"
     y="353.44812">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text718"
     class="st15 st16"
     x="1175.5306"
     y="382.04416">dCDP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text720"
     class="st15 st16"
     x="360.74741"
     y="449.50314">3PPyr</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text722"
     class="st17 st18"
     x="410.62479"
     y="426.49734">NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text724"
     class="st17 st18"
     x="435.24878"
     y="426.49734">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text726"
     class="st17 st18"
     x="440.22931"
     y="426.49734">H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.33130002"
     d="m 446.2,443.81855 -34.2,0.2 m 20.4,0.1 c -4.3,-0.3 -6,-12.3 -6,-12.3 m 3.8,12.1 c 6.1,1.5 5.6,12.5 5.6,12.5"
     class="st75"
     inkscape:label="PHGDH_UBAC2 "
     inkscape:connector-curvature="0"
     id="R_PHGDH_UBAC2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text729"
     class="st17 st18"
     x="427.62769"
     y="465.14575">NAD</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text731"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="356.75916"
     y="399.59976">3PSer</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text733"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="345.07333"
     y="429.83682">Glu</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text735"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="333.53885"
     y="420.90979">AKG</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 377,437.71855 -0.2,-34.2 m -15.7,11.7 c 9.7,-2.9 16,3.2 16,3.2 m -0.2,3.4 c -1.4,5.3 -16.7,5.1 -16.7,5.1"
     class="st76"
     inkscape:connector-curvature="0"
     id="R_PSAT1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 379.1,403.81855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -14,12.2 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="F_PSAT1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.23519993"
     d="m 379.2,351.31855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z"
     class="st77"
     inkscape:label="VPS29_PSPH_PSPHP1  forward"
     inkscape:connector-curvature="0"
     id="F_VPS29_PSPH_PSPHP1" /><text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text740"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="359.90805"
     y="346.62714">Ser</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text742"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="393.64661"
     y="374.83282">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text744"
     class="st17 st26"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="399.87701"
     y="376.83292">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text746"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="402.96588"
     y="374.83289">O</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text748"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="395.1853"
     y="368.10416">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 377,367.81855 c 0.6,2.3 3,3.4 5.1,4.1 2.9,0.8 6,1.1 9,1.1 m 1.7,-11.8 c -5.4,-1.7 -11.7,-0.5 -16,3.2 m 0.3,19.3 c -0.1,-11.4 -0.1,-22.8 -0.2,-34.2"
     class="st76"
     inkscape:label="VPS29_PSPH_PSPHP1 "
     inkscape:connector-curvature="0"
     id="R_VPS29_PSPH_PSPHP1" /><text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text751"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="360.82996"
     y="259.71588">Gly</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text753"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="399.81461"
     y="284.13171">THF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 390.2,284.61855 c 7,-1.3 7,-1.3 7,-1.3 l -6.8,-1.9 1.7,1.7 -1.9,1.5 z m -15.6,36.9 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="B_SHMT1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 425.5,435.31855 c -0.5,-7.1 -0.5,-7.1 -0.5,-7.1 l 3.5,6.2 -2,-1.2 -1,2.1 z m -11.7,11 c -6.3,-2.2 -6.3,-2.2 -6.3,-2.2 l 6.5,-1.7 -1.7,1.9 1.5,2 z"
     class="st73"
     inkscape:label="PHGDH_UBAC2  forward"
     inkscape:connector-curvature="0"
     id="F_PHGDH_UBAC2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text757"
     class="st15 st16"
     x="422.2869"
     y="341.40353">Pyr</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text759"
     class="st17 st18"
     x="396.70538"
     y="319.50906">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text761"
     class="st17 st26"
     x="409.3909"
     y="321.50906">3</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.38170004"
     d="m 398.5,338.71855 c 3.7,-0.3 5.1,-10.5 5.1,-10.5 m -16.8,10.6 26.2,-0.2"
     class="st78"
     inkscape:connector-curvature="0"
     id="R_SDS_SDSL_SRR" /><text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text764"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="141.05353"
     y="304.02942">DHF</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text766"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="136.36797"
     y="245.96878">Folate</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 158.1,279.71855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m 14.1,-2.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
     class="st73"
     inkscape:label="DHFRL1_DHFR_2  forward"
     inkscape:connector-curvature="0"
     id="F_DHFRL1_DHFR_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 159.9,281.31855 -0.2,-34.2 m 15.9,8.5 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.3,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
     class="st79"
     inkscape:label="DHFRL1_DHFR_2 "
     inkscape:connector-curvature="0"
     id="R_DHFRL1_DHFR_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text770"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="184.45857"
     y="280.61414">NADP</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text772"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="179.325"
     y="260.32965">NADPH</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text774"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="179.32498"
     y="272.82965">+H</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text776"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="141.77278"
     y="368.62994">THF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 157.7,343.41855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m 14.1,-2.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
     class="st73"
     inkscape:label="DHFRL1_DHFR_4  forward"
     inkscape:connector-curvature="0"
     id="F_DHFRL1_DHFR_4" /><path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 159.5,345.01855 -0.2,-34.2 m 15.9,8.5 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.2,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
     class="st79"
     inkscape:label="DHFRL1_DHFR_4  "
     inkscape:connector-curvature="0"
     id="R_DHFRL1_DHFR_4" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 161.5,312.61855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m 9.7,7.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
     class="st73"
     inkscape:label="DHFRL1_DHFR_4 "
     inkscape:connector-curvature="0"
     id="B_DHFRL1_DHFR_4" /><text
     style="font-size:10px;font-family:Calibri"
     id="text781"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="181.55092"
     y="341.92856">NADP</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text783"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="177.77963"
     y="322.29248">NADPH</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text785"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="177.77962"
     y="334.79254">+H</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text787"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="122.12817"
     y="433.13483">10-formyl</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text789"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="141.62041"
     y="453.13483">THF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 157.3,407.81855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m 14.1,-2.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
     class="st73"
     inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297  foward"
     inkscape:connector-curvature="0"
     id="F_MTHFD1_AL445665_1_AQP7P4_LOC286297" /><path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 159,409.41855 -0.2,-34.2 m 15.9,8.5 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.3,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
     class="st79"
     inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297 "
     inkscape:connector-curvature="0"
     id="R_MTHFD1_AL445665_1_AQP7P4_LOC286297" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 161.1,377.01855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m 9.7,7.5 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
     class="st73"
     inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297  backward"
     inkscape:connector-curvature="0"
     id="B_MTHFD1_AL445665_1_AQP7P4_LOC286297" /><text
     style="font-size:10px;font-family:Calibri"
     id="text794"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="181.41222"
     y="406.33478">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text796"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="198.51668"
     y="406.33478">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text798"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="203.49713"
     y="406.33481">Pi</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text800"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="176.62868"
     y="387.771">for+ATP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 221.4,395.51855 c 1.4,5.3 17.3,5.1 17.3,5.1 m -1.6,-19.7 c -9.7,-2.9 -16,3.2 -16,3.2 m -14.9,44.3 14.4,0 0,-68 -39.6,0"
     class="st79"
     inkscape:label="MTHFD1_3 "
     inkscape:connector-curvature="0"
     id="R_MTHFD1_3" /><text
     style="font-size:10px;font-family:Calibri"
     id="text803"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="250.68755"
     y="398.89441">NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text805"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="274.24716"
     y="398.89441">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text807"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="250.68761"
     y="411.39444">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text809"
     class="st17 st26"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="256.91809"
     y="413.39441">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text811"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="260.00687"
     y="411.39438">O</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text813"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="242.4368"
     y="378.47998">NADPH+</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text815"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="242.43677"
     y="390.98007">H+CO</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text817"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="265.513"
     y="392.98007">2</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text819"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="261.84116"
     y="348.57727">mTHF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09509993"
     d="m 204.8,436.41855 79.8,0 0,-84 m 16,24.7 c -9.7,-2.9 -16,3.2 -16,3.2 m 0.3,11.4 c 1.4,5.3 17.3,5.1 17.3,5.1"
     class="st80"
     inkscape:connector-curvature="0"
     id="R_MTHFD1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 296,378.11855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z m -9.3,-24.4 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z"
     class="st73"
     inkscape:label="MTHFD1_1  forward"
     inkscape:connector-curvature="0"
     id="F_MTHFD1_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text823"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="309.67828"
     y="399.18741">H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 299.8,398.21855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z m -93.6,36.5 c -6.3,2.3 -6.3,2.3 -6.3,2.3 l 6.5,1.7 -1.7,-1.9 1.5,-2.1 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="B_MTHFD1_1" /><text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text826"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="254.19125"
     y="282.20911">meTHF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 277.6,301.91855 c -1.6,-5.3 -17.5,-4.5 -17.5,-4.5 m 2.3,19.7 c 9.8,2.5 15.9,-3.8 15.9,-3.8 m 0.3,11.1 -0.2,-34.2"
     class="st79"
     inkscape:label="MTHFD2_1 "
     inkscape:connector-curvature="0"
     id="R_MTHFD2_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 280.6,292.01855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -15.6,3.3 c -7,1.6 -7,1.6 -7,1.6 l 6.9,1.6 -1.7,-1.6 1.8,-1.6 z"
     class="st73"
     inkscape:label="MTHFD2_1  forward"
     inkscape:connector-curvature="0"
     id="F_MTHFD2_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 266.3,316.11855 c -7,1.6 -7,1.6 -7,1.6 l 6.9,1.6 -1.7,-1.6 1.8,-1.6 z m 10.5,6.6 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z"
     class="st73"
     inkscape:label="MTHFD2_1  backward"
     inkscape:connector-curvature="0"
     id="B_MTHFD2_1" /><rect
     style="fill:none;stroke:#231f20;stroke-width:7;stroke-linejoin:round;stroke-miterlimit:2"
     height="487.10001"
     width="1218.2"
     class="st81"
     y="682.21857"
     x="248.5"
     id="rect3188" /><text
     style="font-size:10px;font-family:Calibri"
     id="text832"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="229.13246"
     y="320.30942">NADPH</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text834"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="229.66826"
     y="302.43216">NADP</text>
<text
     style="font-size:16.0003109px;font-family:Calibri-Bold"
     id="text836"
     class="st15 st16"
     transform="matrix(0.9999806,0.00622953,-0.00622953,0.9999806,0,0)"
     x="748.04932"
     y="1068.5068">DHF</text>
<text
     style="font-size:15.99927998px;font-family:Calibri-Bold"
     id="text838"
     class="st15 st16"
     transform="matrix(0.99984501,-0.01760548,0.01760548,0.99984501,0,0)"
     x="629.1507"
     y="1083.5598">Folate</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 730.9,1070.9186 c 7.4,-2 7.4,-2 7.4,-2 l -7.2,-2.3 1.8,2.2 -2,2.1 z m -2.4,-14.1 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
     class="st73"
     inkscape:label="DHFRL1_DHFR_5  forward"
     inkscape:connector-curvature="0"
     id="F_DHFRL1_DHFR_5" /><path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 732.5,1069.2186 -34.2,0 m 8.6,-15.9 c -2.9,9.6 3.1,16 3.1,16 m 11.4,-0.2 c 5.3,-1.4 5.2,-17.3 5.2,-17.3"
     class="st79"
     inkscape:label="DHFRL1_DHFR_5 "
     inkscape:connector-curvature="0"
     id="R_DHFRL1_DHFR_5" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 700.1,1066.9186 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z m 7.6,-9.7 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
     class="st73"
     inkscape:label="DHFRL1_DHFR_5  backward"
     inkscape:connector-curvature="0"
     id="B_DHFRL1_DHFR_5" /><text
     style="font-size:9.99962521px;font-family:Calibri"
     id="text843"
     class="st17 st18"
     transform="matrix(0.9997375,0.02291141,-0.02291141,0.9997375,0,0)"
     x="744.8653"
     y="1031.0618">NADP</text>
<text
     style="font-size:9.9998436px;font-family:Calibri"
     id="text845"
     class="st17 st18"
     transform="matrix(0.99991568,-0.012986,0.012986,0.99991568,0,0)"
     x="662.83777"
     y="1056.4205">NADPH+H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text847"
     class="st15 st16"
     transform="matrix(0.99999758,-0.00219903,0.00219903,0.99999758,0,0)"
     x="825.8905"
     y="1075.1088">THF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 812.4,1070.3186 c 7.3,-2 7.3,-2 7.3,-2 l -7.2,-2.3 1.8,2.2 -1.9,2.1 z m -2.4,-14.1 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
     class="st73"
     inkscape:label="DHFRL1_DHFR_6  forward"
     inkscape:connector-curvature="0"
     id="F_DHFRL1_DHFR_6" /><path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 814,1068.5186 -34.2,0 m 8.6,-15.8 c -2.9,9.6 3.1,16 3.1,16 m 11.4,-0.2 c 5.3,-1.4 5.2,-17.3 5.2,-17.3"
     class="st79"
     inkscape:label="DHFRL1_DHFR_6 "
     inkscape:connector-curvature="0"
     id="R_DHFRL1_DHFR_6" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 781.6,1066.3186 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z m 7.5,-9.7 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
     class="st73"
     inkscape:label="DHFRL1_DHFR_6  backward"
     inkscape:connector-curvature="0"
     id="B_DHFRL1_DHFR_6" /><text
     style="font-size:10.00011921px;font-family:Calibri"
     id="text852"
     class="st17 st18"
     transform="matrix(0.99998813,0.00487302,-0.00487302,0.99998813,0,0)"
     x="809.07843"
     y="1042.3011">NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text854"
     class="st17 st18"
     transform="matrix(0.99999791,-0.00204595,0.00204595,0.99999791,0,0)"
     x="756.18549"
     y="1047.5868">NADPH+H</text>
<text
     style="font-size:16.00077438px;font-family:Calibri-Bold"
     id="text856"
     class="st15 st16"
     transform="matrix(0.99995156,0.00984282,-0.00984282,0.99995156,0,0)"
     x="919.18933"
     y="1061.8497">10-formylTHF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 895.7,1056.5186 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z m 2.4,14.1 c 7.3,-2 7.3,-2 7.3,-2 l -7.2,-2.3 1.8,2.2 -1.9,2.1 z"
     class="st73"
     inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297_2  forward"
     inkscape:connector-curvature="0"
     id="F_MTHFD1_AL445665_1_AQP7P4_LOC286297_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 888.6,1068.8186 c 5.3,-1.4 5.2,-17.3 5.2,-17.3 m -19.7,1.5 c -2.9,9.6 3.1,16 3.1,16 m 22.5,-0.1 -34.2,0"
     class="st79"
     inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297_2"
     inkscape:connector-curvature="0"
     id="R_MTHFD1_AL445665_1_AQP7P4_LOC286297_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 875.1,1056.9186 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z m -7.6,9.7 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z"
     class="st73"
     inkscape:label="MTHFD1_AL445665_1_AQP7P4_LOC286297_2  backward"
     inkscape:connector-curvature="0"
     id="B_MTHFD1_AL445665_1_AQP7P4_LOC286297_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text861"
     class="st15 st16"
     transform="matrix(0.9999915,0.00412203,-0.00412203,0.9999915,0,0)"
     x="805.01166"
     y="1025.8337">mTHF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.3247"
     d="m 900.4,1026.9186 c 5.3,-1.1 5.2,-13.8 5.2,-13.8 m -19.8,1.2 c -3,7.7 3.2,12.8 3.2,12.8 m 44.5,25.3 0.6,-25.4 -84.3,-0.1"
     class="st82"
     inkscape:connector-curvature="0"
     id="R_MTHFD1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 853.1,1024.7186 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z m 33.5,-9 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="F_MTHFD1_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text865"
     class="st17 st18"
     transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
     x="876.94342"
     y="1005.7078">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text867"
     class="st17 st26"
     transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
     x="883.17377"
     y="1007.7078">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text869"
     class="st17 st18"
     transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
     x="886.2627"
     y="1005.7078">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 931.6,1049.1186 c 2.2,6.3 2.2,6.3 2.2,6.3 l 1.7,-6.5 -1.9,1.7 -2,-1.5 z m -24.1,-33.9 c -1.3,-7 -1.3,-7 -1.3,-7 l -1.9,6.9 1.7,-1.6 1.5,1.7 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="B_MTHFD1_2" /><text
     style="font-size:16.00037193px;font-family:Calibri-Bold"
     id="text872"
     class="st15 st16"
     transform="matrix(0.99997671,0.00682482,-0.00682482,0.99997671,0,0)"
     x="707.71307"
     y="1025.7979">meTHF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 791.2,1026.6186 -34.2,0 m 26.8,-15.4 c 2.6,9.7 -3.7,15.9 -3.7,15.9 m -11.3,-0.6 c -5.3,-1.6 -4.6,-17.4 -4.6,-17.4"
     class="st79"
     inkscape:connector-curvature="0"
     id="R_MTHFD2_4" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 762.1,1013.9186 c 1.5,-7 1.5,-7 1.5,-7 l 1.7,6.9 -1.6,-1.7 -1.6,1.8 z m -3.3,10.5 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="F_MTHFD2_4" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 789.6,1028.4186 c 7.3,-2 7.3,-2 7.3,-2 l -7.2,-2.3 1.8,2.2 -1.9,2.1 z m -6.7,-13.3 c 1.5,-7 1.5,-7 1.5,-7 l 1.7,6.9 -1.6,-1.7 -1.6,1.8 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="B_MTHFD2_4" /><text
     style="font-size:10px;font-family:Calibri"
     id="text877"
     class="st17 st18"
     transform="matrix(0.99989917,0.01420008,-0.01420008,0.99989917,0,0)"
     x="790.88013"
     y="994.28802">NADPH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text879"
     class="st17 st18"
     transform="matrix(0.99990781,0.01357832,-0.01357832,0.99990781,0,0)"
     x="760.42932"
     y="995.04498">NADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text881"
     class="st15 st16"
     x="315.19269"
     y="786.4632">OAA</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text883"
     class="st15 st16"
     x="942.22101"
     y="658.15649">Gln</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text885"
     class="st15 st16"
     x="1033.4213"
     y="658.15649">Glu</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.56400001"
     d="m 969.4,653.91855 53.9,0 m -19.5,0.5 c 4.6,-0.4 6.2,-11.9 6.2,-11.9 m -5.5,11.7 c -4.5,0.5 -6.6,11.7 -6.6,11.7"
     class="st83"
     inkscape:label="GLS2"
     inkscape:connector-curvature="0"
     id="R_GLS2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text888"
     class="st17 st18"
     x="1000.8987"
     y="636.82635">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text890"
     class="st17 st26"
     x="1013.5844"
     y="638.82635">3</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text892"
     class="st17 st18"
     x="983.43292"
     y="674.4173">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text894"
     class="st17 st26"
     x="989.66345"
     y="676.4173">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text896"
     class="st17 st18"
     x="992.7522"
     y="674.4173">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text898"
     class="st17 st18"
     x="1035.5336"
     y="601.31757">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text900"
     class="st17 st18"
     x="1022.9135"
     y="638.01587">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text902"
     class="st17 st18"
     x="989.93292"
     y="602.9173">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text904"
     class="st17 st26"
     x="1002.6184"
     y="604.9173">3</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text906"
     class="st17 st18"
     x="980.08435"
     y="638.513">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.11560011"
     d="m 1050.4,645.51855 0,-29.9 -92.5,0 0,24 m 78.9,-24.4 c 5,-1.2 4.3,-13.1 4.3,-13.1 m -4.2,12.8 c -5.2,1 -5.3,9.2 -5.3,9.2 m -44,-8.8 c -3.7,0.9 -3.8,9 -3.8,9 m 11,-8.5 c 5,-1.1 4.3,-12 4.3,-12"
     class="st84"
     inkscape:label="#R_gln_synthetase"
     inkscape:connector-curvature="0"
     id="R_GS" /><path
     style="fill:none;stroke:#000000;stroke-width:1.39260006"
     d="m 956.3,660.51855 0,32.4 m 0.4,-9.9 c -2.6,2.5 9.5,6.9 9.5,6.9 m -10,-12.7 c 0.4,-4.4 -9.3,-7.5 -9.3,-7.5"
     class="st85"
     inkscape:label="TransportGln"
     inkscape:connector-curvature="0"
     id="R_TransportGln" /><path
     style="fill:none;stroke:#000000;stroke-width:1.12300003"
     d="m 1052,660.31855 0,32.2 m 0.1,-12.3 c 0.1,5.1 9.8,8.5 9.8,8.5 m -9.9,-9.3 c 0.2,-4.1 -8.4,-8.3 -8.4,-8.3"
     class="st86"
     inkscape:label="TransportGlu"
     inkscape:connector-curvature="0"
     id="R_TransportGlu" /><text
     style="font-size:9.87795448px;font-family:Calibri"
     id="text911"
     class="st17 st87"
     transform="scale(1.0123241,0.98782595)"
     x="926.31677"
     y="681.64825">H</text>
<text
     style="font-size:9.87795448px;font-family:Calibri"
     id="text913"
     class="st17 st87"
     transform="scale(1.0123241,0.98782595)"
     x="962.82196"
     y="702.19128">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text915"
     class="st17 st18"
     x="1032.5765"
     y="674.64575">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text917"
     class="st17 st18"
     x="1070.2865"
     y="694.58521">H</text>
<text
     style="font-size:15.80470657px;font-family:Calibri-Bold"
     id="text919"
     class="st15 st88"
     transform="scale(1.0123241,0.98782595)"
     x="932.36621"
     y="721.383">Gln</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text921"
     class="st15 st16"
     x="1040.6478"
     y="712.59686">Glu</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09260011"
     d="m 969.6,707.11855 63.5,0 m -30.7,0.2 c 5.9,-0.2 7.8,-7.5 7.8,-7.5 m -12.1,7.6 c -4.6,-0.4 -6.8,-9.9 -6.8,-9.9"
     class="st89"
     inkscape:connector-curvature="0"
     id="R_GLS" /><text
     style="font-size:10px;font-family:Calibri"
     id="text924"
     class="st17 st18"
     x="1006.3949"
     y="693.48657">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text926"
     class="st17 st26"
     x="1019.0804"
     y="695.48657">3</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text928"
     class="st17 st18"
     x="982.98663"
     y="694.27856">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text930"
     class="st17 st26"
     x="989.2171"
     y="696.27856">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text932"
     class="st17 st18"
     x="992.30591"
     y="694.27856">O</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text934"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1331.6912"
     y="771.82178">NH</text>
<text
     style="font-size:9.7501936px;font-family:Calibri-Bold"
     id="text936"
     class="st15 st40"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1352.3239"
     y="775.02191">3</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.76709998"
     d="m 1189,777.11855 0.5,-30.4 m 10.5,7.1 c -8.9,1.1 -11.1,9.1 -11.1,9.1 m 0.2,-0.1 c -0.5,5.2 10.5,8.6 10.5,8.6"
     class="st90"
     inkscape:connector-curvature="0"
     id="R_OTC_LEFTY1" /><text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text939"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1180.2643"
     y="782.81091">Orn</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text941"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1187.484"
     y="728.58057">Ci</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text943"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1187.3484"
     y="635.12445">Ci</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text945"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1153.5397"
     y="588.43402">ArgSuc</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text947"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1223.7125"
     y="571.21527">Arg</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text949"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1230.6833"
     y="630.91748">Orn</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text951"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="1132.3175"
     y="625.07318">Asp</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text953"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="1147.2687"
     y="625.07312">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text955"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="1152.249"
     y="625.07312">ATP</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text957"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1113.4318"
     y="629.14063">AMP</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text959"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1132.9337"
     y="629.1405">+</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text961"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1137.9142"
     y="629.14056">PPi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 1179.6,616.11855 c -2.6,-4.9 -15,-1.2 -15,-1.2 m 1.5,11.8 c 10.1,0.2 14.5,-7.4 14.5,-7.4 m -1.1,-15.4 c -3,15.1 4.9,26.9 4.9,26.9"
     class="st76"
     inkscape:label="ASS1 "
     inkscape:connector-curvature="0"
     id="R_ASS1" /><text
     style="font-size:10.00030041px;font-family:Calibri"
     id="text964"
     class="st17 st18"
     transform="matrix(0.99427012,-0.10689679,0.10689679,0.99427012,0,0)"
     x="1114.6914"
     y="680.83099">Fum</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.79009998"
     d="m 1214.6,571.01855 c -16.6,-3.2 -28.6,8.8 -28.6,8.8 m 7.5,-5.6 c 5.9,-1.9 4.1,-12.3 4.1,-12.3"
     class="st91"
     inkscape:connector-curvature="0"
     id="R_ASL_CRCP" /><path
     style="fill:none;stroke:#000000;stroke-width:1.92120004"
     d="m 1248.2,621.11855 c 4.6,-20.3 -6.2,-36.5 -6.2,-36.5 m 18.6,3.2 c -9,-1.2 -13.6,6 -13.6,6 m 0.3,3.6 c 2,3.5 14.6,1.8 14.6,1.8"
     class="st92"
     inkscape:connector-curvature="0"
     id="R_ARG2_ARG1" /><text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text968"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1254.6495"
     y="601.48828">H</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text970"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1260.88"
     y="603.48834">2</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text972"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1263.9689"
     y="601.48822">O</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text974"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1262.8811"
     y="616.68073">Urea</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1186.7,576.11855 c -4.8,5.9 -4.8,5.9 -4.8,5.9 l 7.2,-2.4 -2.7,-0.7 0.3,-2.8 z"
     class="st73"
     inkscape:label="ASL_CRCP  backward"
     inkscape:connector-curvature="0"
     id="B_ASL_CRCP" /><path
     style="fill:none;stroke:#000000;stroke-width:1.3319"
     d="m 1199,562.51855 c -1.6,-4.9 -1.6,-4.9 -1.6,-4.9 l -1,4.9 1.2,-1.2 1.4,1.2 z m 11.8,10.5 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.1 1.8,2.1 -1.8,2.2 z"
     class="st93"
     inkscape:label="ASL_CRCP  forward"
     inkscape:connector-curvature="0"
     id="F_ASL_CRCP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.13980007"
     d="m 1190.5,651.51855 0.1,71.7 m -0.3,-53.8 c 2.4,5.4 15.3,4 15.3,4 m -15.4,-12.9 c 2.4,5.4 15.3,4 15.3,4 m -14.9,35.9 c 1.9,-5.6 15,-5.4 15,-5.4 m -14.6,17.1 c 1.9,-5.6 15,-5.4 15,-5.4"
     class="st94"
     inkscape:label="SLC25A15_SLC25A2_1"
     inkscape:connector-curvature="0"
     id="R_SLC25A15_SLC25A2_1" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text979"
     class="st15 st38"
     transform="matrix(0.99980805,-0.01959226,0.01959226,0.99980805,0,0)"
     x="1201.152"
     y="721.48889">H</text>
<text
     style="font-size:13.99942493px;font-family:Calibri-Bold"
     id="text981"
     class="st15 st38"
     transform="matrix(0.99984109,-0.01782667,0.01782667,0.99984109,0,0)"
     x="1201.3977"
     y="733.09906">Orn</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text983"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1287.2751"
     y="577.22217">Putr</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.36409998"
     d="m 1256.3,636.01855 41.1,0 0,-40.3 m 10.7,7.5 c -6.7,-1.2 -10.2,6.1 -10.2,6.1"
     class="st95"
     inkscape:connector-curvature="0"
     id="R_OGDH_ODC1_OGDHL" /><text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text986"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1308.797"
     y="620.35846">CO</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text988"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1320.6622"
     y="622.35846">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text990"
     class="st15 st16"
     x="1340.1732"
     y="712.76776">GluSA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text992"
     class="st17 st18"
     x="1268.7523"
     y="692.13495">AKG</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text994"
     class="st17 st18"
     x="1299.0814"
     y="692.05975">Glu</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1306.2,700.71855 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.7,6.9 1.6,-1.7 1.5,1.8 z m 21.3,8.8 c 6.3,-2.2 6.3,-2.2 6.3,-2.2 l -6.5,-1.7 1.7,1.9 -1.5,2 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="F_OAT" /><path
     style="fill:none;stroke:#000000;stroke-width:2.21600008"
     d="m 1239.8,707.61855 88.2,0.1 m -28.6,-0.2 c 5.4,-0.7 4.9,-7.6 4.9,-7.6 m -21.6,-4.9 c -1.9,7.9 4.4,12.5 4.4,12.5"
     class="st96"
     inkscape:connector-curvature="0"
     id="R_OAT" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1359,688.51855 c 2.3,6.3 2.3,6.3 2.3,6.3 l 1.7,-6.5 -1.9,1.7 -2.1,-1.5 z"
     class="st73"
     inkscape:label="Transport_Lglu5semialdehyde  backward"
     inkscape:connector-curvature="0"
     id="B_Transport_Lglu5semialdehyde" /><path
     style="fill:none;stroke:#000000;stroke-width:2.34100008"
     d="m 1361,668.81855 0.2,20"
     class="st97"
     inkscape:label="Transport_Lglu5semialdehyde "
     inkscape:connector-curvature="0"
     id="R_Transport_Lglu5semialdehyde" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1362.8,670.21855 c -0.7,-2.4 -1.3,-4.9 -2,-7.3 -0.8,2.4 -1.5,4.8 -2.3,7.3 0.7,-0.6 1.5,-1.2 2.2,-1.8 0.7,0.6 1.4,1.2 2.1,1.8 z"
     class="st73"
     inkscape:label="Transport_Lglu5semialdehyde  forward"
     inkscape:connector-curvature="0"
     id="F_Transport_Lglu5semialdehyde" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1001"
     class="st15 st16"
     x="1336.557"
     y="658.23456">GluSA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1358.4,637.01855 c 2,6.4 2,6.4 2,6.4 l 1.9,-6.4 -1.9,1.6 -2,-1.6 z"
     class="st73"
     inkscape:label="ALDH4A1_2  backward"
     inkscape:connector-curvature="0"
     id="B_ALDH4A1_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1004"
     class="st15 st16"
     x="1352.6332"
     y="608.19745">P5C</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.24119997"
     d="m 1360.4,618.41855 0.1,20.4 m 0.1,-8.4 c -3,-6.6 -10.4,-6.2 -10.4,-6.2"
     class="st98"
     inkscape:connector-curvature="0"
     id="R_ALDH4A1_2" /><text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1007"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1319.298"
     y="638.0332">H</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text1009"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1325.5284"
     y="640.03333">2</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1011"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1328.6173"
     y="638.03326">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1013"
     class="st17 st18"
     transform="matrix(0.99990761,-0.01359275,0.01359275,0.99990761,0,0)"
     x="1371.2954"
     y="643.84912">NADH+H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1015"
     class="st17 st18"
     transform="matrix(0.99939509,-0.03477735,0.03477735,0.99939509,0,0)"
     x="1397.1116"
     y="673.6972">NAD</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1017"
     class="st15 st16"
     x="1442.0248"
     y="606.54315">Pro</text>
<text
     style="font-size:10.00029469px;font-family:Calibri"
     id="text1019"
     class="st17 st18"
     transform="matrix(0.99987054,0.01609049,-0.01609049,0.99987054,0,0)"
     x="1389.0287"
     y="630.53644">NADPH+H</text>
<text
     style="font-size:9.99974251px;font-family:Calibri"
     id="text1021"
     class="st17 st18"
     transform="matrix(0.99922571,-0.03934428,0.03934428,0.99922571,0,0)"
     x="1378.6187"
     y="707.83429">NADP</text>
<text
     style="font-size:9.99983883px;font-family:Calibri"
     id="text1023"
     class="st17 st18"
     transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
     x="1286.8578"
     y="776.54065">NADH</text>
<text
     style="font-size:9.99983883px;font-family:Calibri"
     id="text1025"
     class="st17 st18"
     transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
     x="1311.4819"
     y="776.54071">+</text>
<text
     style="font-size:9.99983883px;font-family:Calibri"
     id="text1027"
     class="st17 st18"
     transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
     x="1316.4624"
     y="776.54065">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1029"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="1303.4719"
     y="727.08441">NAD+H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1031"
     class="st17 st26"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="1333.0753"
     y="729.08441">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1033"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="1336.1642"
     y="727.08441">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.78269994"
     d="m 1360.8,720.31855 0.3,32.5 m -0.2,-19.6 c -1.4,-5 -10.8,-3.5 -10.8,-3.5 m 0.6,11.6 c 7.1,2 10.7,-4.9 10.7,-4.9"
     class="st99"
     inkscape:connector-curvature="0"
     id="R_ALDH4A1_1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1036"
     class="st15 st16"
     x="1350.3373"
     y="771.66528">Glu</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1358.9,750.41855 c 2.3,6.3 2.3,6.3 2.3,6.3 l 1.7,-6.5 -1.9,1.7 -2.1,-1.5 z m -6.9,-10.7 c -7.1,0.9 -7.1,0.9 -7.1,0.9 l 6.8,2.3 -1.6,-1.8 1.9,-1.4 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="B_ALDH4A1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1351,728.11855 c -6.9,1.7 -6.9,1.7 -6.9,1.7 l 7,1.5 -1.8,-1.6 1.7,-1.6 z m 11.8,-3.7 c -0.7,-2.4 -1.3,-4.9 -2,-7.3 -0.8,2.4 -1.5,4.8 -2.3,7.3 0.7,-0.6 1.5,-1.2 2.2,-1.8 0.7,0.5 1.4,1.2 2.1,1.8 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="F_ALDH4A1_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1040"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="888.26978"
     y="706.72406">NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1042"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="906.66333"
     y="706.72406">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1044"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="888.2688"
     y="719.22406">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1046"
     class="st17 st26"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="894.50018"
     y="721.22406">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1048"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="897.58905"
     y="719.224">O</text>
<text
     style="font-size:9.99983883px;font-family:Calibri"
     id="text1050"
     class="st17 st18"
     transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
     x="824.83246"
     y="730.75824">NADH+</text>
<text
     style="font-size:9.99983883px;font-family:Calibri"
     id="text1052"
     class="st17 st18"
     transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
     x="824.83344"
     y="743.2583">H+NH</text>
<text
     style="font-size:6.0936017px;font-family:Calibri"
     id="text1054"
     class="st17 st26"
     transform="matrix(0.99971611,-0.02382647,0.02382647,0.99971611,0,0)"
     x="848.72894"
     y="745.25824">3</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 935,761.21855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.7 -1.6,-1.6 z m -171.9,-16.2 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="B_GLUD1_GLUD2_2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.86580002"
     d="m 941.8,747.41855 c -6.2,1.5 -5.1,14.4 -5.1,14.4 m 21.3,0.1 c 2.7,-9 -4.9,-14.5 -4.9,-14.5 m 103.9,-26.4 c 0,26.3 0,26.3 0,26.3 l -295.7,0"
     class="st100"
     inkscape:connector-curvature="0"
     id="R_GLUD1_GLUD2_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1059,725.01855 c -2.3,-7.3 -2.3,-7.3 -2.3,-7.3 l -2.1,7.3 2.1,-1.9 2.3,1.9 z m -102.6,36.5 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.7 -1.6,-1.6 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="F_GLUD1_GLUD2_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1059"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="956.75903"
     y="773.34814">NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1061"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="980.31866"
     y="773.34814">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1063"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="956.75903"
     y="785.84802">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1065"
     class="st17 st26"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="962.9895"
     y="787.84808">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1067"
     class="st17 st18"
     transform="matrix(0.99999215,0.00396135,-0.00396135,0.99999215,0,0)"
     x="966.07831"
     y="785.84814">O</text>
<text
     style="font-size:9.99983883px;font-family:Calibri"
     id="text1069"
     class="st17 st18"
     transform="matrix(0.99971611,-0.02382646,0.02382646,0.99971611,0,0)"
     x="892.81866"
     y="799.80231">NADPH+</text>
<text
     style="font-size:9.99983883px;font-family:Calibri"
     id="text1071"
     class="st17 st18"
     transform="matrix(0.99971611,-0.02382646,0.02382646,0.99971611,0,0)"
     x="892.81866"
     y="812.30237">H+NH</text>
<text
     style="font-size:6.0936017px;font-family:Calibri"
     id="text1073"
     class="st17 st26"
     transform="matrix(0.99971611,-0.02382646,0.02382646,0.99971611,0,0)"
     x="916.71509"
     y="814.30231">3</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text1075"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="610.36102"
     y="1009.088">Ser</text>
<text
     style="font-size:15.99982166px;font-family:Calibri-Bold"
     id="text1077"
     class="st15 st16"
     transform="matrix(0.99991115,-0.01332996,0.01332996,0.99991115,0,0)"
     x="714.42944"
     y="1011.3351">Gly</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1079"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="652.00781"
     y="1022.0663">THF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 660.6,1009.4186 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z m -2.4,-14.10005 c -7.3,2 -7.3,2 -7.3,2 l 7.3,2.3 -1.8,-2.2 1.8,-2.1 z"
     class="st73"
     inkscape:label="SHMT1_2  backward"
     inkscape:connector-curvature="0"
     id="B_SHMT1_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1082"
     class="st15 st16"
     x="316.81769"
     y="625.53351">Asp</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1084"
     class="st15 st16"
     x="317.24249"
     y="728.39868">Asp</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1086"
     class="st15 st16"
     x="301.33231"
     y="669.98846">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1088"
     class="st15 st16"
     x="289.33328"
     y="654.96118">Glu</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1090"
     class="st15 st16"
     x="359.73318"
     y="710.5979">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1092"
     class="st15 st16"
     x="356.95441"
     y="697.87531">Glu</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 330.6,717.91855 0.2,-81.5 m 0,65.8 c 1.9,5.9 17.6,4.4 17.6,4.4 m -34.6,-41.3 c 5,-3.9 17.8,4.8 17.8,4.8 m -17.9,-17.1 c 4.7,-4.2 18.1,3.8 18.1,3.8 m -1,32.6 c 1.9,5.9 17.6,4.4 17.6,4.4"
     class="st45"
     inkscape:label="SLC25A13_SLC25A12"
     inkscape:connector-curvature="0"
     id="R_SLC25A13_SLC25A12" /><path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 345.2,696.41855 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.1 1.8,2.1 -1.8,2.2 z m -12.3,-57.1 c -2.3,-7.2 -2.3,-7.2 -2.3,-7.2 l -2,7.3 2.1,-1.9 2.2,1.8 z m 13.2,69.9 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.1 1.8,2.1 -1.8,2.2 z"
     class="st45"
     inkscape:label="#SLC25A13_SLC25A12"
     inkscape:connector-curvature="0"
     id="F_SLC25A13_SLC25A12" /><path
     style="fill:none;stroke:#000000;stroke-width:2.49320006"
     d="m 1491.4,754.31855 -49,-0.2"
     class="st101"
     inkscape:label="Transport_serine "
     inkscape:connector-curvature="0"
     id="R_Transport_serine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1443.1,752.01855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
     class="st22"
     inkscape:label="Transport_serine f"
     inkscape:connector-curvature="0"
     id="F_Transport_serine" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1098"
     class="st15 st16"
     x="1409.9398"
     y="758.43781">Ser</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1100"
     class="st15 st16"
     x="1501.6996"
     y="758.50806">Ser</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.48900008"
     d="m 1490.5,773.81855 -48.1,-0.2"
     class="st102"
     inkscape:label="Transport_glycine "
     inkscape:connector-curvature="0"
     id="R_Transport_glycine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1443.1,771.51855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
     class="st22"
     inkscape:label="Transport_glycine  backward"
     inkscape:connector-curvature="0"
     id="B_Transport_glycine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1489.9,775.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st22"
     inkscape:transform-center-y="-3.0492074"
     inkscape:transform-center-x="0.87100132"
     inkscape:label="Transport_glycine  forward"
     inkscape:connector-curvature="0"
     id="F_Transport_glycine" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1105"
     class="st15 st16"
     x="1408.141"
     y="776.79517">Gly</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1107"
     class="st15 st16"
     x="1502.0004"
     y="777.33026">Gly</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.51880002"
     d="m 1497,792.51855 -55.2,-0.2"
     class="st103"
     inkscape:label="TransportFolate"
     inkscape:connector-curvature="0"
     id="R_TransportFolate" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1442.5,790.21855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
     class="st22"
     inkscape:label="TransportFolate f"
     inkscape:connector-curvature="0"
     id="F_TransportFolate" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1111"
     class="st15 st16"
     x="1386.1674"
     y="797.35956">Folate</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1113"
     class="st15 st16"
     x="1501.8568"
     y="795.38885">Folate</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.49620008"
     d="m 1491.2,812.71855 -49.7,-0.2"
     class="st104"
     inkscape:label="SLC16A3_SLC16A1_SLC16A5_2 "
     inkscape:connector-curvature="0"
     id="R_SLC16A3_SLC16A1_SLC16A5_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1116"
     class="st15 st16"
     x="1375.0873"
     y="814.86646">Formate</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1118"
     class="st15 st16"
     x="1501.4066"
     y="815.80499">Formate</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1120"
     class="st17 st18"
     x="485.40158"
     y="115.15945">ATP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 467.4,101.01855 c 0,31.2 0,31.2 0,31.2 m 11.4,-18.7 c -7,-2.9 -11.5,3.3 -11.5,3.3 m 0.2,3.4 c 0.8,5.5 10.2,5.3 10.2,5.3"
     class="st76"
     inkscape:label="GCK_HKDC1_HK1_ADPGK_HK2_HK3 "
     inkscape:connector-curvature="0"
     id="R_GCK_HKDC1_HK1_ADPGK_HK2_HK3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.67910004"
     d="m 467.6,565.81855 0,27.6 0,-27.6 z m 0,12.8 c 0.9,5 10.8,4.8 10.8,4.8 m 0.5,-11 c -6.9,-2.7 -11.3,3 -11.3,3"
     class="st105"
     inkscape:connector-curvature="0"
     id="R_PKM_TMEM54_PKLR_HCN3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 467.4,210.91855 0,31.1 0,-31.1 z m 0.3,14.8 c 0.9,5.5 11.1,5.3 11.1,5.3 m 3.7,-11.9 c -8.8,-2.9 -14.6,3.3 -14.6,3.3"
     class="st76"
     inkscape:connector-curvature="0"
     id="R_PFKP_PFKL_PFKM_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 463.2,324.21855 0,37.2 0,-37.2 z m -0.3,18.2 c 1,5.5 11.8,5.2 11.8,5.2 m 2.5,-13 c -8.1,-2.9 -13.4,3.3 -13.4,3.3"
     class="st76"
     inkscape:connector-curvature="0"
     id="R_GAPDHS_GAPDH_GAPDHP29" /><path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 467.3,389.21855 0,37.2 0,-37.2 z m 0.4,15.4 c 0.8,5.6 9.7,5.3 9.7,5.3 m 2.5,-11.9 c -7.3,-3 -12,3.4 -12,3.4"
     class="st76"
     inkscape:connector-curvature="0"
     id="R_CRISP3_PGK1_MIA3_PGK2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81210005"
     d="m 467,524.81855 c 1.1,4.4 13,4.2 13,4.2 m -13.1,-13 c 0,24.3 0,24.3 0,24.3"
     class="st106"
     inkscape:label="R_ENO1_ENO3_ENO2 "
     inkscape:connector-curvature="0"
     id="R_ENO1_ENO3_ENO2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.58019996"
     d="m 479.9,153.01855 45.9,0 -45.9,0 z m 33,8.4 c 2.6,-5.3 -3.5,-8.6 -3.5,-8.6 m -16.6,0.1 c -4.9,1.2 -4.4,12.7 -4.4,12.7"
     class="st107"
     inkscape:connector-curvature="0"
     id="R_G6PD" /><path
     style="fill:none;stroke:#000000;stroke-width:1.53460002"
     d="m 565.3,154.11855 c 7.9,0 15.7,0 23.6,0 m -8.7,0.1 c -1.9,0.2 -3.2,1.9 -3.9,3.4 -1.3,2.6 -1.9,5.6 -2.3,8.5"
     class="st108"
     inkscape:connector-curvature="0"
     id="R_H6PD_PGLS" /><path
     style="fill:none;stroke:#000000;stroke-width:1.82930005"
     d="m 638.3,154.51855 46.1,0 -46.1,0 z m 36.6,9.4 c 2.4,-5.6 -3.7,-9.1 -3.7,-9.1 m -23.3,-0.2 c -5,1.1 -4.3,12 -4.3,12"
     class="st109"
     inkscape:connector-curvature="0"
     id="R_PGD" /><path
     style="fill:none;stroke:#000000;stroke-width:1.61259997"
     d="m 968,293.11855 -0.2,25.4 m 12.8,-19.5 c -8.2,-1.5 -12.6,4.8 -12.6,4.8 m 0,2.6 c 1.7,4.8 13.1,3 13.1,3"
     class="st110"
     inkscape:label="CMPK2_CMPK1_1"
     inkscape:connector-curvature="0"
     id="R_CMPK2_CMPK1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.54340005"
     d="m 759.4,333.41855 c 2.5,-0.6 3.4,-3.4 4,-5.6 0.5,-2.3 0.7,-4.7 0.7,-7 m -24.6,-0.6 c -1.6,4.5 -0.3,9.8 3.1,13.1 m -13.7,0 c 14.6,-0.1 29.2,-0.2 43.8,-0.3"
     class="st111"
     inkscape:connector-curvature="0"
     id="R_TYMS" /><path
     style="fill:none;stroke:#000000;stroke-width:1.75189996"
     d="m 1088.6,332.81855 c 5.1,-1 3.8,-8.7 3.8,-8.7 m -24.6,-2.4 c -1.7,7.1 3.5,11.2 3.5,11.2 m -16.1,0 49.8,0.2"
     class="st112"
     inkscape:connector-curvature="0"
     id="R_CTPS2_GATM_CTPS1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.82930005"
     d="m 1146.5,332.61855 28.3,0.4 m -18.4,-9.2 c -2.2,5.6 3.9,8.9 3.9,8.9 m 4.8,0 c 5,-0.9 4,-8.9 4,-8.9"
     class="st109"
     inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4"
     inkscape:connector-curvature="0"
     id="R_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_4" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1135"
     class="st15 st38"
     transform="matrix(0.99980805,-0.01959226,0.01959226,0.99980805,0,0)"
     x="1196.0963"
     y="700.7312">H</text>
<text
     style="font-size:13.99942493px;font-family:Calibri-Bold"
     id="text1137"
     class="st15 st38"
     transform="matrix(0.99984109,-0.01782667,0.01782667,0.99984109,0,0)"
     x="1194.2786"
     y="688.07074">Orn</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.52830005"
     d="m 1425.4,612.11855 c 1,-2.3 0.5,-5 -1.1,-6.9 -0.6,-0.7 -1.2,-1.3 -1.9,-1.8 m -20,0.2 c -2.5,0.5 -3.6,3.7 -4.1,6.4 -0.3,2 -0.5,4.1 -0.4,6.1 m 34.9,-12.9 c -16.4,0.1 -32.8,0.1 -49.1,0.2"
     class="st113"
     inkscape:connector-curvature="0"
     id="R_PYCRL_PYCR2_PYCR1_LEFTY1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.80159998"
     d="m 1428.9,640.21855 c 0.3,-6.1 -4.8,-8.7 -4.8,-8.7 m -22.3,0.4 c -3.9,-1.2 -5.4,12.6 -5.4,12.6 m -21.7,-31.8 0,19 75.8,0.1 0,-19"
     class="st114"
     inkscape:connector-curvature="0"
     id="R_PYCRL_PYCR2_PYCR1_LEFTY1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:3.13759995"
     d="m 1050.3,713.41855 c 0,26.9 0,26.9 0,26.9 l -293.5,0 m 98.1,-9.5 c -1.8,5.9 2.3,9.7 2.3,9.7 m 33.9,-0.2 c 3.4,-1.3 3.1,-14.8 3.1,-14.8"
     class="st115"
     inkscape:connector-curvature="0"
     id="R_GLUD1_GLUD2_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1142"
     class="st17 st18"
     transform="matrix(0.99999985,5.3982362e-4,-5.3982362e-4,0.99999985,0,0)"
     x="904.09766"
     y="1005.4383">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1144"
     class="st15 st16"
     x="1486.4927"
     y="394.78244">PPi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1146"
     class="st17 st18"
     x="1531.7222"
     y="374.82935">Pi</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1148"
     class="st15 st16"
     x="1554.2847"
     y="394.81766">Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1150"
     class="st17 st18"
     x="1510.5044"
     y="374.69266">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1152"
     class="st17 st26"
     x="1516.7349"
     y="376.69266">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1154"
     class="st17 st18"
     x="1519.8237"
     y="374.69266">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1156"
     class="st15 st16"
     x="1484.4966"
     y="349.50125">CO</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text1158"
     class="st15 st40"
     x="1503.6685"
     y="352.70145">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1160"
     class="st15 st16"
     x="1556.1343"
     y="349.02563">HCO</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text1162"
     class="st15 st40"
     x="1585.3999"
     y="352.22586">3</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text1164"
     class="st15 st40"
     x="1590.3413"
     y="340.22586">-</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.80649996"
     d="m 1525.5,346.01855 c -5.4,-1.7 -4.9,-14 -4.9,-14 m 10.8,14.3 c 5.5,-1.1 4.1,-10.6 4.1,-10.6 m 9,10.6 -33.9,-0.3"
     class="st116"
     inkscape:label="CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13"
     inkscape:connector-curvature="0"
     id="R_CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1167"
     class="st17 st18"
     x="1532.2759"
     y="326.92114">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1169"
     class="st17 st18"
     x="1511.0825"
     y="328.17014">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1171"
     class="st17 st26"
     x="1517.313"
     y="330.17014">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1173"
     class="st17 st18"
     x="1520.4019"
     y="328.17014">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1424.9,550.31855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -9.1,-14.8 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.8,6.9 1.6,-1.7 1.6,1.8 z"
     class="st73"
     inkscape:label="AGAT  forward"
     inkscape:connector-curvature="0"
     id="F_AGAT" /><path
     style="fill:none;stroke:#000000;stroke-width:2.16529989"
     d="m 1402.1,532.41855 c -2.7,9.7 3.5,15.9 3.5,15.9 m 3.4,-0.2 c 5.4,-1.2 4.9,-14.2 4.9,-14.2 m -25.2,14.2 39.4,0.1"
     class="st117"
     inkscape:connector-curvature="0"
     id="R_AGAT" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1391.4,546.31855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z m 11.6,-10 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.8,6.9 1.6,-1.7 1.6,1.8 z"
     class="st73"
     inkscape:label="AGAT  backward"
     inkscape:connector-curvature="0"
     id="B_AGAT" /><text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text1178"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1439.4275"
     y="543.42334">Orn</text>
<text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text1180"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1360.4196"
     y="542.20752">Arg</text>
<text
     style="font-size:10.00020409px;font-family:Calibri"
     id="text1182"
     class="st17 st18"
     transform="matrix(0.99997957,0.00639185,-0.00639185,0.99997957,0,0)"
     x="1391.7148"
     y="578.39606">H</text>
<text
     style="font-size:6.09382439px;font-family:Calibri"
     id="text1184"
     class="st17 st26"
     transform="matrix(0.99997957,0.00639185,-0.00639185,0.99997957,0,0)"
     x="1397.9453"
     y="580.39606">2</text>
<text
     style="font-size:10.00020409px;font-family:Calibri"
     id="text1186"
     class="st17 st18"
     transform="matrix(0.99997957,0.00639185,-0.00639185,0.99997957,0,0)"
     x="1401.0333"
     y="578.396">O</text>
<text
     style="font-size:10.000103px;font-family:Calibri"
     id="text1188"
     class="st17 st18"
     transform="matrix(0.99968968,0.0249107,-0.0249107,0.99968968,0,0)"
     x="1421.3773"
     y="552.20471">NH</text>
<text
     style="font-size:6.09376287px;font-family:Calibri"
     id="text1190"
     class="st17 st26"
     transform="matrix(0.99968968,0.0249107,-0.0249107,0.99968968,0,0)"
     x="1434.0627"
     y="554.20477">3</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.58570004"
     d="m 1372.7,556.21855 0,8 59.7,0 m -27.9,0.1 c -5.2,1.1 -4.6,11.9 -4.6,11.9 m 11.8,-2.8 c 1.3,-5.8 -4.6,-9 -4.6,-9"
     class="st118"
     inkscape:connector-curvature="0"
     id="R_arginineAmidinohydrolase" /><text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text1193"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1443.032"
     y="560.49847">Ci</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1195"
     class="st15 st16"
     x="141.67799"
     y="620.84399">Asn</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1197"
     class="st17 st18"
     x="169.63359"
     y="597.4563">Glu</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1199"
     class="st17 st18"
     x="183.491"
     y="597.4563">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1201"
     class="st17 st18"
     x="188.4715"
     y="597.4563">AMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1203"
     class="st17 st18"
     x="207.97339"
     y="597.4563">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1205"
     class="st17 st18"
     x="212.95389"
     y="597.4563">PPi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1207"
     class="st17 st18"
     x="235.44168"
     y="597.802">Gln+ATP+H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1209"
     class="st17 st26"
     x="280.53448"
     y="599.802">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1211"
     class="st17 st18"
     x="283.6228"
     y="597.802">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.13490009"
     d="m 177.6,614.01855 c 45.3,0 90.7,0.1 136,0.1 m -53.3,-0.7 c 4.3,-2.2 4.3,-7.9 4.6,-12.1 l 0,-0.6 0,-0.5 m -62.9,4.2 c -1.9,3.5 0.5,7.2 3.5,9.1"
     class="st119"
     inkscape:connector-curvature="0"
     id="R_ASNS" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1214"
     class="st17 st18"
     x="178.00999"
     y="646.13007">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1216"
     class="st17 st26"
     x="184.24049"
     y="648.13007">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1218"
     class="st17 st18"
     x="187.32939"
     y="646.13007">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1220"
     class="st17 st18"
     x="215.13109"
     y="645.87531">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1222"
     class="st17 st26"
     x="227.8167"
     y="647.87531">3</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1224"
     class="st15 st16"
     x="312.49149"
     y="443.98465">Fum</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1226"
     class="st15 st16"
     x="311.30301"
     y="503.79126">Mal</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1228"
     class="st17 st18"
     x="289.62579"
     y="470.02274">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1230"
     class="st17 st26"
     x="295.8562"
     y="472.02274">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1232"
     class="st17 st18"
     x="298.94458"
     y="470.02274">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1234"
     class="st15 st16"
     x="310.03931"
     y="565.5257">OAA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1236"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="364.86237"
     y="538.48999">GTP</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1238"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="378.13837"
     y="544.30634">GDP+CO</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text1240"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="412.61111"
     y="546.30634">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.3204"
     d="m 397.8,557.61855 c 6.3,-1 6,-11.8 6,-11.8 m -31.2,-3.5 c -2.3,9.4 2.6,15.5 2.6,15.5 m 62.1,-0.2 -98.3,0.2"
     class="st120"
     inkscape:connector-curvature="0"
     id="R_PEPCK" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1243"
     class="st15 st16"
     x="562.0647"
     y="582.62531">Iso</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1245"
     class="st17 st18"
     x="583.12042"
     y="558.49048">NADPH</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1247"
     class="st15 st16"
     x="666.13904"
     y="582.9212">AKG</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1249"
     class="st17 st18"
     x="584.34894"
     y="600.24438">NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1251"
     class="st17 st18"
     x="634.66632"
     y="558.13007">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1253"
     class="st17 st26"
     x="646.53149"
     y="560.13007">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1255"
     class="st15 st16"
     x="254.8035"
     y="672.10089">Fum</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1257"
     class="st17 st18"
     x="235.65359"
     y="644.21405">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1259"
     class="st17 st26"
     x="248.33908"
     y="646.21405">3</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1261"
     class="st15 st16"
     x="354.87671"
     y="645.8938">Ala</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 430.6,634.41855 c -1.4,-7 -1.4,-7 -1.4,-7 l -1.7,6.9 1.6,-1.7 1.5,1.8 z m 25.2,-8.7 c -2.2,-6.3 -2.2,-6.3 -2.2,-6.3 l -1.7,6.5 1.9,-1.7 2,1.5 z"
     class="st73"
     inkscape:label="NIT2 b"
     inkscape:connector-curvature="0"
     id="B_NIT2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 410.3,635.21855 c -0.5,-2.3 -1,-4.7 -1.4,-7 -0.6,2.3 -1.2,4.6 -1.7,6.9 0.5,-0.6 1.1,-1.1 1.6,-1.7 0.4,0.6 1,1.2 1.5,1.8 l 0,0 z m -21.4,4.9 c -2.5,0.6 -4.9,1.3 -7.4,1.9 2.4,0.8 4.8,1.6 7.2,2.4 -0.6,-0.7 -1.2,-1.5 -1.8,-2.2 0.8,-0.7 1.4,-1.4 2,-2.1 l 0,0 z"
     class="st73"
     inkscape:label="NIT2"
     inkscape:connector-curvature="0"
     id="F_NIT2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1265"
     class="st17 st18"
     x="396.95239"
     y="626.41815">AKG</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1267"
     class="st17 st18"
     x="420.85379"
     y="626.40259">Glu</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1269"
     class="st15 st16"
     x="409.09311"
     y="1219.8303">Biomass</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 434.5,1275.0186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
     class="st69"
     inkscape:label="biomass_synthesis f"
     inkscape:connector-curvature="0"
     id="F_biomass_synthesis" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 436.5,1224.9186 0,50.5"
     class="st69"
     inkscape:label="biomass_synthesis"
     inkscape:connector-curvature="0"
     id="R_biomass_synthesis" /><path
     style="fill:none;stroke:#000000;stroke-width:1.68139994"
     d="m 407.6,610.21855 c -5.4,-0.8 -5.1,-9.5 -5.1,-9.5 m 35.5,-3.8 c 2.8,7.9 -3.2,13.1 -3.2,13.1 m 14.4,-0.2 c -62.3,0 -62.3,0 -62.3,0"
     class="st121"
     inkscape:label="#R_LDHD"
     inkscape:connector-curvature="0"
     id="R_LDH" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1274"
     class="st17 st18"
     x="657.13702"
     y="176.49825">NADPH+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1276"
     class="st17 st18"
     x="657.13702"
     y="188.99825">H+CO2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1278"
     class="st17 st18"
     x="498.32352"
     y="174.68045">NADPH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1280"
     class="st17 st18"
     x="528.11365"
     y="174.68045">+H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1282"
     class="st17 st18"
     x="420.31329"
     y="593.42896">NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1284"
     class="st17 st18"
     x="444.93729"
     y="593.42896">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1286"
     class="st17 st18"
     x="449.91779"
     y="593.42896">H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.90479994"
     inkscape:connector-curvature="0"
     d="m 467.5,711.91855 -0.2,-89.3 m 0.3,71.6 c 1.4,5.7 13.2,4.2 13.2,4.2 m -13.5,-30 c -1.7,-4.3 -14.4,-3.9 -14.4,-3.9"
     class="st122"
     id="R_MPC1_MPC2_MPC1L" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 465,710.11855 c 2.3,6.3 2.3,6.3 2.3,6.3 l 1.6,-6.5 -1.9,1.7 -2,-1.5 z"
     class="st73"
     inkscape:label="MPC1_MPC2_MPC1L  forward"
     inkscape:connector-curvature="0"
     id="F_MPC1_MPC2_MPC1L" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1290"
     class="st17 st18"
     x="432.4104"
     y="750.59888">NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1292"
     class="st17 st18"
     x="434.51151"
     y="767.7298">CoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1294"
     class="st17 st18"
     x="485.1048"
     y="782.6712">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1296"
     class="st17 st26"
     x="496.97"
     y="784.6712">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1298"
     class="st17 st18"
     x="484.4744"
     y="761.19745">NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1300"
     class="st17 st18"
     x="485.61499"
     y="772.3714">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1302"
     class="st17 st18"
     x="580.08624"
     y="699.8714">Mal</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1304"
     class="st17 st18"
     x="520.5755"
     y="664.80096">Mal</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.25819993"
     d="m 559.6,784.71855 -0.1,-252.5 m 0.1,159.4 c 1.4,5.6 13.3,4.2 13.3,4.2 m -13.4,-29.7 c -1.7,-4.2 -14.5,-3.9 -14.5,-3.9"
     class="st123"
     inkscape:label="SLC25A1"
     inkscape:connector-curvature="0"
     id="R_SLC25A1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1307"
     class="st15 st16"
     x="554.77374"
     y="523.11255">Cit</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 568.4,536.41855 c 2.2,-7.3 2.2,-7.3 2.2,-7.3 l 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="ACO1_IREB2 b"
     inkscape:connector-curvature="0"
     id="B_ACO1_IREB2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 568.6,562.11855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st14"
     inkscape:label="ACO1_IREB2 f"
     inkscape:connector-curvature="0"
     id="F_ACO1_IREB2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.92060006"
     d="m 570.4,535.51855 c 0,27.3 0,27.3 0,27.3"
     class="st124"
     inkscape:label="ACO1_IREB2"
     inkscape:connector-curvature="0"
     id="R_ACO1_IREB2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1312"
     class="st17 st18"
     x="887.51202"
     y="262.06564">2 Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 477.8,123.71855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12.4,8 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st30"
     inkscape:label="GCK_HKDC1_HK1_ADPGK_HK2_HK3  f"
     inkscape:connector-curvature="0"
     id="F_GCK_HKDC1_HK1_ADPGK_HK2_HK3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 477.8,229.21855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12,10.7 c 1.7,7.3 1.7,7.3 1.7,7.3 l 1.7,-7.3 -1.7,1.8 -1.7,-1.8 z"
     class="st30"
     inkscape:label="PFKP_PFKL_PFKM_1 f"
     inkscape:connector-curvature="0"
     id="F_PFKP_PFKL_PFKM_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 473.7,345.71855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12.6,13.6 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st30"
     inkscape:label="GAPDHS_GAPDH_GAPDHP29"
     inkscape:connector-curvature="0"
     id="F_GAPDHS_GAPDH_GAPDHP29" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 479.8,527.21855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -14.7,10.9 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st30"
     inkscape:label="ENO1_ENO3_ENO2 f"
     inkscape:connector-curvature="0"
     id="F_ENO1_ENO3_ENO2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 477.9,581.61855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -12.4,10.4 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z"
     class="st30"
     inkscape:label="PKM_TMEM54_PKLR_HCN3 f"
     inkscape:connector-curvature="0"
     id="F_PKM_TMEM54_PKLR_HCN3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 403.9,602.11855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -15.8,5.8 -7.3,2.2 7.3,2.2 -1.8,-2.2 1.8,-2.2 z"
     class="st30"
     inkscape:label="LDH f"
     inkscape:connector-curvature="0"
     id="F_LDH" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 514.9,160.51855 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m 6.5,-5.4 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.2 1.8,2.2 -1.8,2.2 z"
     class="st30"
     inkscape:label="G6PD"
     inkscape:connector-curvature="0"
     id="F_G6PD" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 676.8,162.21855 c -1,5.2 -1,5.2 -1,5.2 l -2.4,-5.3 1.9,1.3 1.5,-1.2 z m 5.2,-5.6 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.2 1.8,2.2 -1.8,2.2 z"
     class="st30"
     inkscape:label="PGD f"
     inkscape:connector-curvature="0"
     id="F_PGD" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09750009"
     d="m 790.5,176.41855 c 0,29.5 0,29.5 0,29.5 m -12.7,-23.8 c 7.8,-2.3 12.6,3.5 12.6,3.5 m -0.3,7 c -1,5 -10.4,4.3 -10.4,4.3"
     class="st125"
     inkscape:label="PRPS2_PRPS1_PRPS1L1"
     inkscape:connector-curvature="0"
     id="R_PRPS2_PRPS1_PRPS1L1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 764.8,168.11855 c 7.2,-0.3 7.2,-0.3 7.2,-0.3 l -6.1,-3.9 1.1,2.6 -2.2,1.6 z"
     class="st32"
     inkscape:transform-center-y="13.19671"
     inkscape:transform-center-x="-17.870394"
     inkscape:label="RPIA_LOC101060545 f"
     inkscape:connector-curvature="0"
     id="F_RPIA_LOC101060545" /><path
     style="fill:none;stroke:#000000;stroke-width:1.17589998"
     d="m 732.7,157.71855 33.8,8.2"
     class="st126"
     inkscape:transform-center-y="9.1713454"
     inkscape:transform-center-x="7.5511886"
     inkscape:label="RPIA_LOC101060545"
     inkscape:connector-curvature="0"
     id="R_RPIA_LOC101060545" /><path
     style="fill:none;stroke:#000000;stroke-width:1.13479996"
     d="m 739,148.51855 32,-6.4"
     class="st127"
     inkscape:transform-center-y="-9.5755519"
     inkscape:transform-center-x="6.2972653"
     inkscape:label="RPE_LOC729020"
     inkscape:connector-curvature="0"
     id="R_RPE_LOC729020" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 740.3,146.41855 c -6.6,2.9 -6.6,2.9 -6.6,2.9 l 7.1,1.5 -1.9,-2 1.4,-2.4 z"
     class="st32"
     inkscape:transform-center-y="-7.1245069"
     inkscape:transform-center-x="22.076699"
     inkscape:label="RPE_LOC729020 f"
     inkscape:connector-curvature="0"
     id="F_RPE_LOC729020" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 780.2,198.61855 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z m 12.4,6.6 c -2,6.9 -2,6.9 -2,6.9 l -2.4,-6.8 2.2,1.7 2.2,-1.8 z"
     class="st30"
     inkscape:label="PRPS2_PRPS1_PRPS1L1 f"
     inkscape:connector-curvature="0"
     id="F_PRPS2_PRPS1_PRPS1L1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1328"
     class="st17 st18"
     x="928.5589"
     y="209.07054">4 Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.00309992"
     d="m 628.9,518.91855 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m -6.4,-11.7 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 12.1,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 14.1,11.6 -72.4,-0.2 m 19.7,-0.3 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.3,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
     class="st128"
     inkscape:label="ACLY"
     inkscape:connector-curvature="0"
     id="R_ACLY" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1331"
     class="st17 st18"
     x="619.48761"
     y="501.60864">Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1333"
     class="st17 st18"
     x="925.4632"
     y="502.06665">CoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1335"
     class="st17 st18"
     x="978.2464"
     y="502.37036">3ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1337"
     class="st17 st18"
     x="944.37335"
     y="502.11053">2 NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1339"
     class="st17 st18"
     x="1005.5902"
     y="502.01004">Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1341"
     class="st17 st18"
     x="1022.222"
     y="502.37036">CO2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1343"
     class="st17 st18"
     x="935.09015"
     y="537.14966">2 NADPH</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.00309992"
     d="m 990.8,518.11855 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 37.1,-11.1 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m -20.9,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m -56.6,11.1 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 5.6,-11.1 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 28.6,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 42.5,11.6 -117.3,-0.2 m 10.7,-0.3 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 4.3,-11 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
     class="st128"
     inkscape:label="MVD"
     inkscape:connector-curvature="0"
     id="R_MVD" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1346"
     class="st17 st18"
     x="916.46899"
     y="537.34601">2 H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1348"
     class="st17 st18"
     x="975.79724"
     y="537.38495">3 ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1350"
     class="st17 st18"
     x="1083.433"
     y="539.12915">2 ippPP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1352"
     class="st17 st18"
     x="1092.3324"
     y="502.40256">2 PPi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.96599996"
     d="m 1113.5,519.01855 -25,-0.5 m 13.7,-0.2 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.2,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
     class="st129"
     inkscape:label="ARID4B_GGPS1_FDPS_FDPSP7_2"
     inkscape:connector-curvature="0"
     id="R_ARID4B_GGPS1_FDPS_FDPSP7_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1355"
     class="st17 st18"
     x="1146.4008"
     y="536.18677">fPP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1357"
     class="st17 st18"
     x="1147.5316"
     y="500.91135">15 H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1359"
     class="st17 st26"
     x="1166.1605"
     y="502.91135">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1361"
     class="st17 st18"
     x="1169.2484"
     y="500.91135">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1363"
     class="st17 st18"
     x="1244.015"
     y="500.13596">2 PPi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1365"
     class="st17 st18"
     x="1178.6937"
     y="500.73166">13 NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1367"
     class="st17 st18"
     x="1269.6381"
     y="499.95636">for</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1369"
     class="st17 st18"
     x="1219.3802"
     y="500.49734">2 CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1371"
     class="st17 st26"
     x="1238.5746"
     y="502.49734">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1373"
     class="st17 st18"
     x="1162.7885"
     y="536.02271">13 NADPH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1375"
     class="st17 st18"
     x="1208.9027"
     y="536.07941">16 H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1377"
     class="st17 st18"
     x="1230.308"
     y="535.75806">10 O</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1379"
     class="st17 st26"
     x="1249.3265"
     y="537.75806">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.82200003"
     d="m 861.2,464.41855 c 5.9,-1 4.4,-9.6 4.4,-9.6 m -19,9.5 29.3,0.3 m -15.1,-0.1 c -6,1.2 -5.5,10.5 -5.5,10.5"
     class="st130"
     inkscape:label="MCAT_FASN"
     inkscape:connector-curvature="0"
     id="R_MCAT_FASN" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1382"
     class="st17 st18"
     x="1064.4486"
     y="447.78546">14 H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 888.8,422.31855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -27.6,0.3 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 39.9,9.6 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
     class="st30"
     inkscape:label="AcAcACPSynthesis f"
     inkscape:connector-curvature="0"
     id="F_AcAcACPSynthesis" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 477.8,777.11855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m 0,-10.5 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m 0,-10.5 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -10.5,38.3 c -2.1,6.9 -2.1,6.9 -2.1,6.9 l -2.3,-6.8 2.2,1.7 2.2,-1.8 z"
     class="st30"
     inkscape:label="DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB F"
     inkscape:connector-curvature="0"
     id="F_DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB" /><path
     style="fill:none;stroke:#000000;stroke-width:2.37849998"
     d="m 443.6,735.91855 -27.4,0 0,127.5 116.3,0 m -60.4,0.2 c 7.3,-1.5 7.3,-12.6 7.3,-12.6 m 17.7,12.5 c -7.6,1.4 -8.5,11 -8.5,11 m -25.1,-11 c -7.6,1.4 -8.5,11 -8.5,11 m -15.9,-11 c -7.6,1.4 -8.5,11 -8.5,11 m 8.7,-11.2 c 7.3,-1.5 7.3,-12.6 7.3,-12.6"
     class="st131"
     inkscape:label="PC"
     inkscape:connector-curvature="0"
     id="R_PC" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1387"
     class="st17 st18"
     x="437.9422"
     y="842.4212">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1389"
     class="st17 st18"
     x="475.73709"
     y="842.85181">Pi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1391"
     class="st17 st18"
     x="420.13361"
     y="882.27466">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1393"
     class="st17 st18"
     x="444.71021"
     y="881.94067">HCO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1395"
     class="st17 st26"
     x="462.80591"
     y="883.94067">3</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1397"
     class="st17 st26"
     x="465.89481"
     y="876.44067">-</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1399"
     class="st17 st18"
     x="485.21021"
     y="881.94067">H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 530.5,861.11855 c 6.9,2.1 6.9,2.1 6.9,2.1 l -6.8,2.3 1.7,-2.2 -1.8,-2.2 z m -86,-10.4 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 33,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st32"
     inkscape:label="PC f"
     inkscape:connector-curvature="0"
     id="F_PC" /><path
     style="fill:none;stroke:#000000;stroke-width:1.53359997"
     d="m 562.6,822.11855 c 4.2,1.1 4.2,1.1 4.2,1.1 l -4.4,1.6 1.2,-1.4 -1,-1.3 z m -6.5,-9.6 c 0.1,-5.5 0.1,-5.5 0.1,-5.5 l -3.5,4.6 2.1,-0.8 1.3,1.7 z"
     class="st132"
     inkscape:label="CS f"
     inkscape:connector-curvature="0"
     id="F_CS" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1403"
     class="st17 st18"
     x="681.67023"
     y="783.07056">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1405"
     class="st17 st18"
     x="683.4339"
     y="716.35669">H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.49890006"
     d="m 662.8,725.01855 c -1,6.8 -7.1,8.5 -7.1,8.5 m 45.3,-7.2 c -1,6.8 -7.1,8.5 -7.1,8.5 m -8.9,-11 c -1,6.8 -7.1,8.5 -7.1,8.5 m -39,-5.5 c 1,6.8 7.1,8.5 7.1,8.5 m -13.6,3.7 c 26,-9.2 53,-8.9 79.3,1"
     class="st133"
     inkscape:label="IDH2"
     inkscape:connector-curvature="0"
     id="R_IDH2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81630003"
     d="m 638.9,767.21855 c -3.8,4 -3.8,4 -3.8,4 l 1.6,-6.8 0.4,2.8 1.8,0 z m -5.4,-13.8 c -6.3,-1.4 -6.3,-1.4 -6.3,-1.4 l 4.4,4.1 -0.4,-2 2.3,-0.7 z"
     class="st134"
     inkscape:label="IDH3 b"
     inkscape:connector-curvature="0"
     id="B_IDH3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.49890006"
     d="m 632.4,755.01855 c 26,9.2 53,8.9 79.3,-1 m -74.1,13.2 c 1,-6.8 7.1,-8.5 7.1,-8.5 m 40.3,11 c -1,-6.8 -7.1,-8.5 -7.1,-8.5 m 23.1,6 c -1,-6.8 -7.1,-8.5 -7.1,-8.5 m -29.9,10.7 c -1,-6.8 -7.1,-8.5 -7.1,-8.5"
     class="st133"
     inkscape:connector-curvature="0"
     id="R_IDH3" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1410"
     class="st17 st18"
     x="789.9563"
     y="767.94257">NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1412"
     class="st17 st18"
     x="814.58044"
     y="767.94257">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1414"
     class="st17 st18"
     x="789.9563"
     y="780.44257">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1416"
     class="st17 st18"
     x="796.18683"
     y="780.44257">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1418"
     class="st17 st18"
     x="801.1673"
     y="780.44257">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1420"
     class="st17 st26"
     x="813.03253"
     y="782.44257">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1422"
     class="st17 st18"
     x="509.7952"
     y="894.0257">NADH+H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1424"
     class="st17 st18"
     x="489.20441"
     y="902.28931">NAD</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09549999"
     d="m 429.3,916.81855 c -7.3,-1.3 -7.3,-10.9 -7.3,-10.9 m 29.9,10.9 c -7.3,-1.3 -7.3,-10.9 -7.3,-10.9 m 32.8,10.9 c -7.3,-1.3 -7.3,-10.9 -7.3,-10.9 m 22.9,10.8 c 7.3,-1.3 7.3,-10.9 7.3,-10.9 m 76.2,10.9 -167.7,0 0,-187.3 34.9,0"
     class="st135"
     inkscape:label="ME2_ME3_1"
     inkscape:connector-curvature="0"
     id="R_ME2_ME3_1" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 424,906.71855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 22.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 25.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -31,-176.2 c 6.4,-2 6.4,-2 6.4,-2 l -6.6,-2.3 1.7,2.2 -1.5,2.1 z"
     class="st30"
     inkscape:label="ME2_ME3_1 f"
     inkscape:connector-curvature="0"
     id="F_ME2_ME3_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1428"
     class="st17 st18"
     x="457.70239"
     y="898.8313">NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1430"
     class="st17 st18"
     x="441.25998"
     y="898.8313">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1432"
     class="st17 st18"
     x="415.7493"
     y="898.8147">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1434"
     class="st17 st26"
     x="427.6145"
     y="900.8147">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1436"
     class="st17 st18"
     x="503.78641"
     y="944.25116">NADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.14289999"
     d="m 429.3,920.51855 c -7.3,1.4 -7.3,11.4 -7.3,11.4 m 29.9,-11.4 c -7.3,1.4 -7.3,11.4 -7.3,11.4 m 32.8,-11.4 c -7.3,1.4 -7.3,11.4 -7.3,11.4 m 38.1,-11.3 c 7.2,1.7 7.2,14.6 7.2,14.6 m 61.2,-14.6 -177,0 0,-199.5 42.5,0"
     class="st136"
     inkscape:label="ME2_ME3_2"
     inkscape:connector-curvature="0"
     id="R_ME2_ME3_2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 424,930.01855 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m 22.5,0 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m 25.5,0 c -2,4.9 -2,4.9 -2,4.9 l -1.3,-5.6 1.6,1.7 1.7,-1 z m -31,-207 c 6.5,-1.8 6.5,-1.8 6.5,-1.8 l -6.5,-2.5 1.7,2.2 -1.7,2.1 z"
     class="st30"
     inkscape:label="ME2_ME3_2 f"
     inkscape:connector-curvature="0"
     id="F_ME2_ME3_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1440"
     class="st17 st18"
     x="456.02231"
     y="944.76099">NADPH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1442"
     class="st17 st18"
     x="440.8992"
     y="944.5813">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1444"
     class="st17 st18"
     x="415.7981"
     y="944.5813">CO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1446"
     class="st17 st26"
     x="427.66339"
     y="946.5813">2</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.10339999"
     d="m 615.9,579.61855 c 5.9,-1.5 5.4,-12.9 5.4,-12.9 m 15.5,12.5 c 5.9,-1.3 4.4,-12.5 4.4,-12.5 m 14,12.5 -72.4,-0.2 m 19.7,-0.3 c -5.9,1.4 -4.4,13.7 -4.4,13.7 m 1.3,-12.8 c 5.9,-1.5 5.4,-12.9 5.4,-12.9"
     class="st137"
     inkscape:label="IDH1"
     inkscape:connector-curvature="0"
     id="R_IDH1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1449"
     class="st17 st18"
     x="619.24744"
     y="558.70239">H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 327.8,483.61855 c 0,-27.3 0,-27.3 0,-27.3 m -0.4,15.6 c -1.1,-6 -11.6,-4.8 -11.6,-4.8"
     class="st14"
     inkscape:label="FH_2"
     inkscape:connector-curvature="0"
     id="R_FH_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 330.1,482.71855 c -2.2,7.3 -2.2,7.3 -2.2,7.3 l -2.2,-7.3 2.2,1.8 2.2,-1.8 z"
     class="st14"
     inkscape:label="FH_2 f"
     inkscape:connector-curvature="0"
     id="F_FH_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 329.9,456.91855 c -2.2,-7.3 -2.2,-7.3 -2.2,-7.3 l -2.2,7.3 2.2,-1.8 2.2,1.8 z m -14.7,12 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z"
     class="st14"
     inkscape:label="FH_2 b"
     inkscape:connector-curvature="0"
     id="B_FH_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1454"
     class="st17 st18"
     x="287.3587"
     y="527.83325">NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1456"
     class="st17 st18"
     x="271.14529"
     y="544.677">NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1458"
     class="st17 st18"
     x="295.76929"
     y="544.677">+</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1460"
     class="st17 st18"
     x="300.74979"
     y="544.677">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1462"
     class="st15 st16"
     x="429.36963"
     y="1131.9838">Q</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1464"
     class="st15 st16"
     x="350.36279"
     y="1132.7025">NADH</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1466"
     class="st15 st16"
     x="457.80908"
     y="1199.7504">4 H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.06859994"
     d="m 474.1998,1181.2711 -2.8,5.9 -2,-6.1 2.3,1.6 2.5,-1.4 z m 12.4,-39.3 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m 29.4,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z"
     class="st138"
     inkscape:label="Complex1ROS f"
     inkscape:connector-curvature="0"
     id="F_Complex1ROS" /><path
     style="fill:none;stroke:#000000;stroke-width:2.06859994"
     d="m 761.84776,1178.6878 -2.8,5.9 -2,-6.1 2.3,1.6 z m 27.25948,-37.9976 -2.8,-5.9 -2,6.1 2.3,-1.6 z m 52.82373,-0.1976 -2.8,-5.9 -2,6.1 2.3,-1.6 z"
     class="st138"
     inkscape:label="Complex3 f"
     inkscape:connector-curvature="0"
     id="F_Complex3"
     sodipodi:nodetypes="ccccccccccccccc" /><path
     style="fill:none;stroke:#000000;stroke-width:2.06859994"
     d="m 1050.1,1177.9186 -2.8,5.9 -2,-6.1 2.3,1.6 2.5,-1.4 z m 96.4,-35.6 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m -72,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z"
     class="st138"
     inkscape:label="Complex4 f"
     inkscape:connector-curvature="0"
     id="F_Complex4" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1471"
     class="st15 st16"
     x="1186.5951"
     y="1132.6877">ADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1473"
     class="st15 st16"
     x="1258.2738"
     y="1131.0793">ATP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1475"
     class="st15 st16"
     x="1288.1302"
     y="1131.2004">2 H</text>
<text
     style="font-size:9.75px;font-family:Calibri-Bold"
     id="text1477"
     class="st15 st40"
     x="1309.9506"
     y="1134.3997">2</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1479"
     class="st15 st16"
     x="1314.8929"
     y="1131.2004">O</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1481"
     class="st15 st16"
     x="1224.5297"
     y="1132.1653">Pi</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1483"
     class="st15 st16"
     x="1234.349"
     y="1192.5237">4 H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1485"
     class="st15 st16"
     x="1337.7094"
     y="1131.2004">4 H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.11870003"
     d="m 1310.4,1155.6186 0,-13.8 m -106.2,-2 0,16.2 142.6,0 0,-16.2 m -116.3,-0.5 0,16.2 m 43.9,0.1 0,-13.8 m -29.7,13.8 0,25.4"
     class="st139"
     inkscape:label="ATPsynthase "
     inkscape:connector-curvature="0"
     id="R_ATPsynthase" /><path
     style="fill:none;stroke:#000000;stroke-width:2.06859994"
     d="m 1313.3,1141.9186 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m 36,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z m -72,0 -2.8,-5.9 -2,6.1 2.3,-1.6 2.5,1.4 z"
     class="st138"
     inkscape:label="ATPsynthase f"
     inkscape:connector-curvature="0"
     id="F_ATPsynthase" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1495"
     class="st15 st16"
     x="177.9417"
     y="839.77655">AKG</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1497"
     class="st15 st16"
     x="286.39868"
     y="840.57635">AKG</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 275.8,835.31855 -60.2,-0.3 m 44.6,0.3 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -26.7,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7"
     class="st45"
     inkscape:label="SLC25A11"
     inkscape:connector-curvature="0"
     id="R_SLC25A11" /><path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 267.4,821.81855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 l 0,0 z"
     class="st140"
     inkscape:label="SLC25A11 b"
     inkscape:connector-curvature="0"
     id="B_SLC25A11" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1501"
     class="st15 st38"
     x="258.91681"
     y="813.65851">Mal</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1503"
     class="st15 st38"
     x="218.61449"
     y="814.12427">Mal</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.35560012"
     d="m 233.9,824.21855 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 40.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st46"
     inkscape:label="SLC25A11 f"
     inkscape:connector-curvature="0"
     id="F_SLC25A11" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1506"
     class="st17 st18"
     x="1286.9183"
     y="796.95239">HCO</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1508"
     class="st17 st26"
     x="1305.014"
     y="798.95239">3</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1510"
     class="st17 st26"
     x="1308.1029"
     y="791.45239">-</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1512"
     class="st17 st18"
     x="1261.7601"
     y="797.07349">2 ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1514"
     class="st17 st18"
     x="1312.8011"
     y="797.28931">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1516"
     class="st17 st18"
     x="1215.6556"
     y="796.61255">2 ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1518"
     class="st17 st18"
     x="1247.1156"
     y="797.24536">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1198.1,755.61855 c 6.9,-1.7 6.9,-1.7 6.9,-1.7 l -7,-1.5 1.8,1.6 -1.7,1.6 z m -6.3,-8.1 c -1.9,-7.4 -1.9,-7.4 -1.9,-7.4 l -2.4,7.2 2.2,-1.8 2.1,2 z"
     class="st73"
     inkscape:label="OTC_LEFTY1 f"
     inkscape:connector-curvature="0"
     id="F_OTC_LEFTY1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1521"
     class="st17 st18"
     x="1207.1527"
     y="756.75415">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1205.4,705.01855 c 5.4,1.6 5.4,1.6 5.4,1.6 l -5.8,1.7 1.6,-1.6 -1.2,-1.7 z m 0,-12 c 5.4,1.6 5.4,1.6 5.4,1.6 l -5.8,1.7 1.6,-1.6 -1.2,-1.7 z m -12.9,-39.4 c -2.6,-7.2 -2.6,-7.2 -2.6,-7.2 l -1.7,7.4 2,-2 2.3,1.8 z"
     class="st73"
     inkscape:label="SLC25A15_SLC25A2_1 f"
     inkscape:connector-curvature="0"
     id="F_SLC25A15_SLC25A2_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1165.5,612.21855 c -6.9,1.7 -6.9,1.7 -6.9,1.7 l 7,1.5 -1.8,-1.6 1.7,-1.6 z m 14.8,-3.2 c -0.8,-7.6 -0.8,-7.6 -0.8,-7.6 l -3.4,6.8 2.5,-1.4 1.7,2.2 z"
     class="st73"
     inkscape:label="ASS1 f"
     inkscape:connector-curvature="0"
     id="F_ASS1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1260.6,601.11855 c 6.9,-1.7 6.9,-1.7 6.9,-1.7 l -7,-1.5 1.8,1.6 -1.7,1.6 z m -14.1,15.4 c 0.8,7.6 0.8,7.6 0.8,7.6 l 3.4,-6.8 -2.4,1.4 -1.8,-2.2 z"
     class="st73"
     inkscape:label="ARG2_ARG1 f"
     inkscape:connector-curvature="0"
     id="F_ARG2_ARG1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1307.9,604.11855 c 6.9,-1.7 6.9,-1.7 6.9,-1.7 l -7,-1.5 1.8,1.6 -1.7,1.6 z m -8.3,-7.4 c -1.9,-7.4 -1.9,-7.4 -1.9,-7.4 l -2.4,7.2 2.2,-1.8 2.1,2 z"
     class="st73"
     inkscape:label="OGDH_ODC1_OGDHL f"
     inkscape:connector-curvature="0"
     id="F_OGDH_ODC1_OGDHL" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1410.9,573.21855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 19,-6.5 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z"
     class="st73"
     inkscape:label="arginineAmidinohydrolase"
     inkscape:connector-curvature="0"
     id="F_arginineAmidinohydrolase" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1226.5,773.71855 -7.3,2.2 7.3,2.2 -1.8,-2.2 1.8,-2.2 z m 6.9,9 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 15.5,0.5 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z"
     class="st73"
     inkscape:label="CPS1"
     inkscape:connector-curvature="0"
     id="F_CPS1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1424.1,609.91855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 7.6,-4.7 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z"
     class="st73"
     inkscape:label="PYCRL_PYCR2_PYCR1_LEFTY1_1 f"
     inkscape:connector-curvature="0"
     id="F_PYCRL_PYCR2_PYCR1_LEFTY1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1427.1,638.71855 c 1.7,6.9 1.7,6.9 1.7,6.9 l 1.5,-7 -1.6,1.8 -1.6,-1.7 z m 25.3,-21.9 c -1.8,-7.4 -1.8,-7.4 -1.8,-7.4 l -2.5,7.2 2.2,-1.7 2.1,1.9 z"
     class="st73"
     inkscape:label="PYCRL_PYCR2_PYCR1_LEFTY1_2 f"
     inkscape:connector-curvature="0"
     id="F_PYCRL_PYCR2_PYCR1_LEFTY1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 389.7,362.01855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="path2280" /><path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 376.4,277.61855 c 1.4,5.3 17.3,5.1 17.3,5.1 m -78.9,-8.4 c 36.8,-1.5 60.9,1.7 60.9,1.7 m 0.6,47.2 -0.1,-55.9 m -15.7,21.2 c 9.7,-2.9 16,3.2 16,3.2"
     class="st79"
     inkscape:connector-curvature="0"
     id="R_SHMT1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 314.9,275.71855 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z m 63.2,-8.2 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -14.8,22 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
     class="st73"
     inkscape:connector-curvature="0"
     id="F_SHMT1" /><text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1534"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="333.75421"
     y="294.88434">H</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text1536"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="339.98471"
     y="296.88437">2</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1538"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="343.07361"
     y="294.8844">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 401.7,328.31855 c 1.3,-7 1.3,-7 1.3,-7 l 1.9,6.9 -1.7,-1.7 -1.5,1.8 z m 10.4,8.6 c 6.3,2.2 6.3,2.2 6.3,2.2 l -6.5,1.7 1.7,-1.9 -1.5,-2 z"
     class="st73"
     inkscape:label="SDS_SDSL_SRR"
     inkscape:connector-curvature="0"
     id="F_SDS_SDSL_SRR" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18140006"
     d="m 453.8,622.71855 0,19.5 -67.5,0 m 23.1,-11 c -2.7,7 3.5,11.5 3.5,11.5 m 10.9,-0.1 c 5.4,-0.9 4.9,-10.3 4.9,-10.3"
     class="st141"
     inkscape:label="NIT2"
     inkscape:connector-curvature="0"
     id="R_NIT2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1542"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="301.05325"
     y="582.61121">Glu</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1544"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="288.98755"
     y="601.8775">AKG</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 327.2,600.61855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m -7,-4.3 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
     class="st73"
     inkscape:label="GOT1_GOT2_GOT1L1_2 bb"
     inkscape:connector-curvature="0"
     id="B_GOT1_GOT2_GOT1L1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.06480002"
     d="m 329.3,603.91855 -0.2,-29.4 m -12.3,8.1 c 7.6,-2.9 12.6,3.3 12.6,3.3 m 0,3.4 c -0.9,5.5 -11.2,5.2 -11.2,5.2"
     class="st142"
     inkscape:label="GOT1_GOT2_GOT1L1_2"
     inkscape:connector-curvature="0"
     id="R_GOT1_GOT2_GOT1L1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 331,575.81855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -10.2,7.7 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
     class="st73"
     inkscape:label="GOT1_GOT2_GOT1L1_2 f"
     inkscape:connector-curvature="0"
     id="F_GOT1_GOT2_GOT1L1_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1549"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="302.24371"
     y="760.4939">Glu</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1551"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="288.6842"
     y="751.92932">AKG</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 328.8,764.61855 c 2,7.3 2,7.3 2,7.3 l 2.3,-7.3 -2.2,1.8 -2.1,-1.8 z m -8,-4.3 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
     class="st73"
     inkscape:label="GOT2_GOT1L1_1 b"
     inkscape:connector-curvature="0"
     id="B_GOT2_GOT1L1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.06480002"
     d="m 330.9,768.01855 -0.2,-29.4 m -13.3,8.1 c 8.1,-2.9 13.4,3.3 13.4,3.3 m -0.1,3.3 c -1,5.4 -11.9,5.2 -11.9,5.2"
     class="st142"
     inkscape:label="GOT2_GOT1L1_1"
     inkscape:connector-curvature="0"
     id="R_GOT2_GOT1L1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 332.6,739.81855 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z m -11.2,7.7 c -7,-1.3 -7,-1.3 -7,-1.3 l 6.9,-1.9 -1.7,1.7 1.8,1.5 z"
     class="st73"
     inkscape:label="GOT2_GOT1L1_1 f"
     inkscape:connector-curvature="0"
     id="F_GOT2_GOT1L1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5236001"
     d="m 270.8,636.91855 c -1.4,6.1 -13.6,4.6 -13.6,4.6 m 58.1,-13.7 -44.2,0 0,24.1"
     class="st143"
     inkscape:label="FH_3"
     inkscape:connector-curvature="0"
     id="R_FH_3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 203.3,605.11855 c -1.5,-5.1 -1.5,-5.1 -1.5,-5.1 l -1.8,5.5 1.7,-1.5 1.6,1.1 z m -25.5,6.7 c -6.3,2.2 -6.3,2.2 -6.3,2.2 l 6.5,1.7 -1.7,-1.9 1.5,-2 z"
     class="st30"
     inkscape:connector-curvature="0"
     id="F_ASNS" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 306.6,623.91855 c 6.3,-2.2 6.3,-2.2 6.3,-2.2 l -6.5,-1.7 1.7,1.9 -1.5,2 z m -87.9,7 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st30"
     inkscape:connector-curvature="0"
     id="path2462" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5697"
     d="m 174.6,621.51855 134,0.1 m -89.1,9.8 c 2.6,-5.3 -3.5,-9.1 -3.5,-9.1 m -23.9,-0.1 c -5,1.5 -4.6,13.1 -4.6,13.1"
     class="st144"
     inkscape:connector-curvature="0"
     id="R_ASRGL1_ASPG" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 327.8,536.41855 c -1.1,6 -11.6,4.8 -11.6,4.8 m 11.6,5.6 c 0,-30.5 0,-30.5 0,-30.5 m 0,14.1 c -1.1,-6 -11.6,-4.8 -11.6,-4.8"
     class="st14"
     inkscape:label="MDH1_MDH1B "
     inkscape:connector-curvature="0"
     id="R_MDH1_MDH1B" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 315.6,539.51855 c -4.9,2 -4.9,2 -4.9,2 l 5.6,1.3 -1.7,-1.6 1,-1.7 z m 14.6,6.2 c -2.2,7.3 -2.2,7.3 -2.2,7.3 l -2.2,-7.3 2.2,1.8 2.2,-1.8 z"
     class="st14"
     inkscape:label="MDH1_MDH1B f"
     inkscape:connector-curvature="0"
     id="F_MDH1_MDH1B" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 329.9,517.91855 c -2.2,-7.3 -2.2,-7.3 -2.2,-7.3 l -2.2,7.3 2.2,-1.8 2.2,1.8 z m -14.3,9.5 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z"
     class="st14"
     inkscape:label="MDH1_MDH1B b"
     inkscape:connector-curvature="0"
     id="B_MDH1_MDH1B" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 853.3,730.91855 c 1.7,-6.9 1.7,-6.9 1.7,-6.9 l 1.5,7 -1.6,-1.7 -1.6,1.6 z m -94.9,7.7 c -7.3,2.3 -7.3,2.3 -7.3,2.3 l 7.3,2 -1.9,-2.1 1.9,-2.2 z"
     class="st73"
     inkscape:label="GLUD1_GLUD2_1 F"
     inkscape:connector-curvature="0"
     id="F_GLUD1_GLUD2_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1564"
     class="st17 st18"
     x="843.83331"
     y="243.37524">Asp</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1566"
     class="st15 st16"
     x="1104.5219"
     y="229.47775">AMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1568"
     class="st17 st18"
     x="1032.9047"
     y="239.12524">GTP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1570"
     class="st17 st18"
     x="1056.3265"
     y="238.95825">Asp</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1572"
     class="st17 st18"
     x="1070.4886"
     y="207.11935">Fum</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1574"
     class="st17 st18"
     x="1038.6117"
     y="207.13495">GDP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1576"
     class="st15 st16"
     x="1190.1205"
     y="274.58914">GMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1578"
     class="st17 st18"
     x="1022.7562"
     y="251.87625">NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1580"
     class="st17 st18"
     x="1044.2269"
     y="251.96504">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1582"
     class="st17 st26"
     x="1050.4574"
     y="253.96504">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1584"
     class="st17 st18"
     x="1053.5463"
     y="251.96504">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1586"
     class="st17 st18"
     x="1096.4867"
     y="251.55885">NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1588"
     class="st17 st18"
     x="1124.9867"
     y="251.55885">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1590"
     class="st17 st18"
     x="1136.9867"
     y="251.55885">AMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1592"
     class="st17 st18"
     x="1062.2269"
     y="251.96504">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1594"
     class="st17 st18"
     x="1078.7269"
     y="251.96504">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1596"
     class="st17 st26"
     x="1091.4125"
     y="253.96504">3</text>
<path
     style="fill:#786721;stroke:#000000;stroke-width:2.5"
     d="m 1165.6,258.31855 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z m 7.2,8.5 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -25.2,-8.5 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z m -16.5,0 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z m -21,0 c -1.6,-4.7 -1.6,-4.7 -1.6,-4.7 l -2.4,4.6 2.1,-1.1 1.9,1.2 z"
     class="st145"
     inkscape:label="GMPS f"
     inkscape:connector-curvature="0"
     id="F_GMPS" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1599"
     class="st17 st18"
     x="1159.4867"
     y="251.55885">PPi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.45089996"
     d="m 1017,234.51855 0,30 156.7,0 m -13.1,-0.1 c 4.8,-1 3,-7.4 3,-7.4 m -76.3,-1.9 c -1.5,6.1 4.8,9.3 4.8,9.3 m -24.3,-9.3 c -1.5,6.1 4.8,9.3 4.8,9.3 m 70,0 c 4.8,-1 3,-7.4 3,-7.4 m -19.5,7.4 c 4.8,-1 3,-7.4 3,-7.4 m -79.3,-1.9 c -1.5,6.1 4.8,9.3 4.8,9.3 m -19.7,-9.3 c -1.5,6.1 4.8,9.3 4.8,9.3 m 65.4,0 c 4.8,-1 3,-7.4 3,-7.4"
     class="st146"
     inkscape:label="GMPS"
     inkscape:connector-curvature="0"
     id="R_GMPS" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1602"
     class="st17 st18"
     x="1089.4623"
     y="295.44165">NADPH</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1126.6,282.21855 c -1.6,4.7 -1.6,4.7 -1.6,4.7 l -2.4,-4.6 2.1,1.1 1.9,-1.2 z m -18,0 c -1.6,4.7 -1.6,4.7 -1.6,4.7 l -2.4,-4.6 2.1,1.1 1.9,-1.2 z m 64,-4.2 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.3,-1.9 1.9,2.1 -1.8,2.2 z"
     class="st22"
     inkscape:connector-curvature="0"
     id="path2738" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1605"
     class="st17 st18"
     x="1122.9066"
     y="295.62234">H</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1607"
     class="st17 st18"
     x="1045.0922"
     y="295.91525">NADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1609"
     class="st17 st18"
     x="1070.9701"
     y="295.55396">NH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1611"
     class="st17 st26"
     x="1083.6556"
     y="297.55396">3</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.7529"
     d="m 1076.8,287.31855 c -1.5,-7.6 4.8,-11.6 4.8,-11.6 m -24.2,11.6 c -1.5,-7.6 4.8,-11.6 4.8,-11.6 m 59.4,0.1 c 4.8,0.9 3,6.9 3,6.9 m -21,-6.9 c 4.8,0.9 3,6.9 3,6.9 m -95.6,-48.5 0,41.6 162.2,0"
     class="st147"
     inkscape:label="GMPR2_GMPR"
     inkscape:connector-curvature="0"
     id="R_GMPR2_GMPR" /><path
     style="fill:none;stroke:#000000;stroke-width:1.92519999"
     d="m 1257.8,269.81855 c -24.9,0 -24.9,0 -24.9,0 m 16.5,9.6 c 2.4,-5.9 -3.6,-9.5 -3.6,-9.5 m -2.6,0.1 c -5,0.9 -4.4,9.3 -4.4,9.3"
     class="st148"
     inkscape:label="GUK1_1"
     inkscape:connector-curvature="0"
     id="R_GUK1_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1615"
     class="st17 st18"
     x="1305.1234"
     y="296.55396">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1617"
     class="st17 st26"
     x="1311.3539"
     y="298.55396">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1619"
     class="st17 st18"
     x="1314.4427"
     y="296.55396">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.89830005"
     d="m 1324,269.41855 c -24.2,0 -24.2,0 -24.2,0 m 15.6,11.1 c 2.4,-6.8 -3.6,-11 -3.6,-11"
     class="st149"
     inkscape:label="RRM2B_TXN_RRM1_RRM2B_1"
     inkscape:connector-curvature="0"
     id="R_RRM2B_TXN_RRM1_RRM2B_1" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1622"
     class="st15 st16"
     x="1336.0267"
     y="274.81174">dGDP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1624"
     class="st15 st16"
     x="1189.1234"
     y="226.54515">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1626"
     class="st17 st18"
     x="1144.3539"
     y="205.21504">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1628"
     class="st17 st18"
     x="1162.7318"
     y="204.82245">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1630"
     class="st17 st18"
     x="1225.3851"
     y="248.99045">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1632"
     class="st17 st26"
     x="1231.6156"
     y="250.99045">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1634"
     class="st17 st18"
     x="1234.7035"
     y="248.99045">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.77349997"
     d="m 1239.9,223.41855 c -21.1,0 -21.1,0 -21.1,0 m 12.6,11.4 c 2.4,-7 -3.6,-11.3 -3.6,-11.3"
     class="st150"
     inkscape:label="RRM2B_TXN_RRM1_RRM2B_2"
     inkscape:connector-curvature="0"
     id="R_RRM2B_TXN_RRM1_RRM2B_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1637"
     class="st15 st16"
     x="1251.2035"
     y="225.97145">dADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1639"
     class="st17 st18"
     x="989.38702"
     y="354.02756">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1641"
     class="st17 st18"
     x="1006.057"
     y="353.84204">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.82930005"
     d="m 1014.9,334.41855 c 7.4,-1.9 7.4,-1.9 7.4,-1.9 l -7.2,-2.4 1.8,2.2 -2,2.1 z m -5.5,5.8 c 2.4,5.1 2.4,5.1 2.4,5.1 l 2,-5.2 -2.1,1.3 -2.3,-1.2 z"
     class="st109"
     inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3 b"
     inkscape:connector-curvature="0"
     id="B_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.55369997"
     d="m 1004.5,332.21855 c -4.9,1.2 -3.1,9.2 -3.1,9.2 m 10.5,0.8 c 1.6,-6.3 -4.9,-9.6 -4.9,-9.6 m 10.9,-0.3 -25.4,-0.2"
     class="st151"
     inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3"
     inkscape:connector-curvature="0"
     id="R_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1645"
     class="st17 st18"
     x="484.89191"
     y="128.75026">ADP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1647"
     class="st15 st16"
     x="448.1004"
     y="156.49535">G6P</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1649"
     class="st15 st16"
     x="450.83908"
     y="90.690155">Glc</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 465.3,424.91855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z m 11.2,-16.2 c 1.6,0.7 3.3,1.4 4.9,2 -1.9,0.4 -3.8,0.8 -5.6,1.3 0.6,-0.5 1.1,-1 1.7,-1.6 -0.4,-0.5 -0.7,-1.1 -1,-1.7 l 0,0 z"
     class="st14"
     inkscape:label="CRISP3_PGK1_MIA3_PGK2 f"
     inkscape:connector-curvature="0"
     id="F_CRISP3_PGK1_MIA3_PGK2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 447.4,607.61855 7.3,2.2 -7.3,2.2 1.8,-2.2 -1.8,-2.2 z m -10.6,-6.6 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st30"
     inkscape:label="LDH b"
     inkscape:connector-curvature="0"
     id="B_LDH" /><path
     style="fill:none;stroke:#000000;stroke-width:1.82930005"
     d="m 861.8,126.21855 0,-11.3 30,0 m -20.8,-8.8 c -1.7,5.6 4.7,8.7 4.7,8.7 m 3.2,-0.2 c 4.9,-1.1 3.2,-8.9 3.2,-8.9"
     class="st109"
     inkscape:label="PFKP_PFKL_PFKM_3"
     inkscape:connector-curvature="0"
     id="R_PFKP_PFKL_PFKM_3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 888.2,116.91855 c 7.3,-2.2 7.3,-2.2 7.3,-2.2 l -7.3,-2.2 1.8,2.2 -1.8,2.2 z m -6.9,-9.3 c 1.5,-4.3 1.5,-4.3 1.5,-4.3 l 1.4,4.7 -1.4,-1.3 -1.5,0.9 z"
     class="st30"
     inkscape:label="PFKP_PFKL_PFKM_3 b"
     inkscape:connector-curvature="0"
     id="B_PFKP_PFKL_PFKM_3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.71169996"
     d="m 859.5,122.51855 c 2.1,6.2 2.1,6.2 2.1,6.2 l 2.1,-6.2 -2.1,1.5 -2.1,-1.5 z m 9.8,-14.9 c 1.5,-4.3 1.5,-4.3 1.5,-4.3 l 1.4,4.7 -1.4,-1.3 -1.5,0.9 z"
     class="st152"
     inkscape:label="PFKP_PFKL_PFKM_3 f"
     inkscape:connector-curvature="0"
     id="F_PFKP_PFKL_PFKM_3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.74290001"
     d="m 491.3,814.71855 61.5,3.7 m 11.8,25.5 c -4.4,0.5 -8.8,-1.3 -11.3,-4.5 -2.5,-3.3 -2.7,-7.5 -0.6,-10.8 2.2,-3.4 6.4,-5.3 10.8,-5.1 m -9.8,29.2 c -3.7,-13.4 -3.5,-27.4 0.7,-40.9"
     class="st153"
     inkscape:label="CS"
     inkscape:connector-curvature="0"
     id="R_CS" /><path
     style="fill:none;stroke:#000000;stroke-width:1.63900006"
     d="m 662.5,768.41855 c 2.1,4.7 2.1,4.7 2.1,4.7 l 1,-5.3 -1.4,1.6 -1.7,-1 z m 37.5,-1.5 c 2.1,4.7 2.1,4.7 2.1,4.7 l 1,-5.3 -1.4,1.6 -1.7,-1 z m 9.6,-14.8 c 6.3,-1.4 6.3,-1.4 6.3,-1.4 l -4.4,4.1 0.4,-2 -2.3,-0.7 z m -26.1,17.8 c 2.1,4.7 2.1,4.7 2.1,4.7 l 1,-5.3 -1.4,1.6 -1.7,-1 z"
     class="st154"
     inkscape:label="IDH3 f"
     inkscape:connector-curvature="0"
     id="F_IDH3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81630003"
     d="m 640,727.51855 c -3.8,-4 -3.8,-4 -3.8,-4 l 1.6,6.8 0.4,-2.8 1.8,0 z m -6.5,12.6 c -6.3,1.4 -6.3,1.4 -6.3,1.4 l 4.4,-4.1 -0.4,2 2.3,0.7 z"
     class="st134"
     inkscape:label="IDH2 b"
     inkscape:connector-curvature="0"
     id="B_IDH2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.63900006"
     d="m 661.1,725.61855 c 2.1,-4.7 2.1,-4.7 2.1,-4.7 l 1,5.3 -1.4,-1.6 -1.7,1 z m 38.1,1.5 c 2.1,-4.7 2.1,-4.7 2.1,-4.7 l 1,5.3 -1.4,-1.6 -1.7,1 z m -15.7,-3 c 2.1,-4.7 2.1,-4.7 2.1,-4.7 l 1,5.3 -1.4,-1.6 -1.7,1 z m 26.1,17.3 c 6.3,1.4 6.3,1.4 6.3,1.4 l -4.4,-4.1 0.4,2 -2.3,0.7 z"
     class="st154"
     inkscape:connector-curvature="0"
     id="path2385" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81599998"
     d="m 775.5,787.91855 c 4.5,4.3 4.5,4.3 4.5,4.3 l -1.5,-6.1 -0.8,2.2 -2.2,-0.4 z m 7.8,-13.5 c 3.8,-1 3.8,-1 3.8,-1 l -2.8,3.2 0.3,-1.7 -1.3,-0.5 z"
     class="st55"
     inkscape:label="DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL f"
     inkscape:connector-curvature="0"
     id="F_DLSTP1_DLD_OGDH_PDHX_DLST_DHTKD1_OGDHL" /><path
     style="fill:none;stroke:#000000;stroke-width:1.81599998"
     d="m 551.9,886.51855 c -4,4 -4,4 -4,4 l 5.5,-0.9 -1.9,-1 0.4,-2.1 z m 9.4,-8.4 c -4.3,-4.3 -4.3,-4.3 -4.3,-4.3 l 1.3,6 0.8,-2.1 2.2,0.4 z"
     class="st55"
     inkscape:label="MDH2 f"
     inkscape:connector-curvature="0"
     id="F_MDH2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 572.4,693.91855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -10.5,-159.2 c -2.3,-6.3 -2.3,-6.3 -2.3,-6.3 l -1.6,6.5 1.9,-1.7 2,1.5 z"
     class="st30"
     inkscape:label="SLC25A1 f"
     inkscape:connector-curvature="0"
     id="F_SLC25A1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 561.5,781.41855 c -2.3,6.3 -2.3,6.3 -2.3,6.3 l -1.6,-6.5 1.9,1.7 2,-1.5 z m -16.4,-117.8 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z"
     class="st73"
     inkscape:label="SLC25A1 b"
     inkscape:connector-curvature="0"
     id="B_SLC25A1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 639.9,566.81855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.1,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -16.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 50.9,14.5 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st22"
     inkscape:label="IDH1 f"
     inkscape:connector-curvature="0"
     id="F_IDH1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 637.5,509.41855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -16.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.1,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 51.9,11.5 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st22"
     inkscape:label="ACLY f"
     inkscape:connector-curvature="0"
     id="F_ACLY" /><path
     style="fill:none;stroke:#000000;stroke-width:2.41549993"
     d="m 1094.7,430.01855 -120.1,-0.2 m 106.7,0.4 c -6,1.3 -5.5,10.6 -5.5,10.6 m -88,-10.9 c -6,1.3 -5.5,10.6 -5.5,10.6 m 48,-10.5 c -6,1.3 -5.5,10.6 -5.5,10.6 m 3.2,-10.2 c 5.9,-1.3 4.4,-11.9 4.4,-11.9 m 46.7,11.9 c 5.9,-1.3 4.4,-11.9 4.4,-11.9 m -93.9,11.4 c 5.9,-1.3 4.4,-11.9 4.4,-11.9 m 58.8,11.9 c 5.9,-1.3 4.4,-11.9 4.4,-11.9"
     class="st155"
     inkscape:label="OLAH_FASN "
     inkscape:connector-curvature="0"
     id="R_OLAH_FASN" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1667"
     class="st17 st18"
     x="722.22681"
     y="501.87915">CoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.96720004"
     d="m 740.8,519.01855 -25,-0.5 m 12.1,-0.2 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.3,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
     class="st156"
     inkscape:label="ACAT1_ACAT2"
     inkscape:connector-curvature="0"
     id="R_ACAT1_ACAT2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 728.4,509.41855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 11.1,11.6 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z"
     class="st30"
     inkscape:label="ACAT1_ACAT2 f"
     inkscape:connector-curvature="0"
     id="F_ACAT1_ACAT2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1671"
     class="st17 st18"
     x="710.4895"
     y="542.85089">AcCoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22309995"
     d="m 716.3,520.51855 c -6.4,-2.1 -6.4,-2.1 -6.4,-2.1 l 6.5,-1.8 -1.7,1.9 1.6,2 z m 5.8,7.9 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st157"
     inkscape:label="ACAT1_ACAT2 B"
     inkscape:connector-curvature="0"
     id="B_ACAT1_ACAT2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1674"
     class="st15 st16"
     x="749.35974"
     y="522.77277">AcAcCoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.83369994"
     d="m 841.4,518.71855 c -5.9,1 -4.4,9.5 -4.4,9.5 m -18.1,-9.5 c -5.9,1 -4.4,9.5 -4.4,9.5 m 7.6,-9.6 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 21.3,11.7 -37.5,-0.4"
     class="st158"
     inkscape:label="HMGCS1_HMGCS2 "
     inkscape:connector-curvature="0"
     id="R_HMGCS1_HMGCS2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1677"
     class="st17 st18"
     x="828.9563"
     y="536.06281">H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1679"
     class="st17 st26"
     x="835.18683"
     y="538.06281">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1681"
     class="st17 st18"
     x="838.2757"
     y="536.06281">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1683"
     class="st17 st18"
     x="798.9895"
     y="535.35089">AcCoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1685"
     class="st17 st18"
     x="818.22681"
     y="501.87915">CoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22309995"
     d="m 846,521.01855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -21,-11.6 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st157"
     inkscape:label="HMGCS1_HMGCS2 f"
     inkscape:connector-curvature="0"
     id="F_HMGCS1_HMGCS2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1688"
     class="st15 st16"
     x="855.85974"
     y="522.77277">HMGCoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22309995"
     d="m 1035.4,520.81855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -102.4,-11.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 25.9,0.4 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 33,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 18,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 16.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st157"
     inkscape:label="MVD f"
     inkscape:connector-curvature="0"
     id="F_MVD" /><path
     style="fill:none;stroke:#000000;stroke-width:1.85309994"
     d="m 1269.2,518.61855 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m -24.9,10.1 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m -27.9,10.1 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m -51.9,10.1 c 5.9,-1.2 5.4,-10.1 5.4,-10.1 m 57.3,10.3 c -5.9,1 -4.4,9.6 -4.4,9.6 m -15.8,-9.6 c -5.9,1 -4.4,9.6 -4.4,9.6 m -36.9,-10.1 c -5.9,1 -4.4,9.6 -4.4,9.6 m 105.2,-9.1 -133.5,-0.2 m 9.1,-0.1 c -5.9,1 -4.4,9.6 -4.4,9.6 m 4.3,-9.5 c 5.9,-1.2 5.4,-10.1 5.4,-10.1"
     class="st159"
     inkscape:label="DHCR24_LEFTY1"
     inkscape:connector-curvature="0"
     id="R_DHCR24_LEFTY1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22309995"
     d="m 1113.4,520.51855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -11.1,-10.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st157"
     inkscape:label="ARID4B_GGPS1_FDPS_FDPSP7_2 f"
     inkscape:connector-curvature="0"
     id="F_ARID4B_GGPS1_FDPS_FDPSP7_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22309995"
     d="m 1281,520.71855 c 6.4,-2.1 6.4,-2.1 6.4,-2.1 l -6.5,-1.8 1.7,1.9 -1.6,2 z m -7.8,-11.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -19.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -22.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -46.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -22.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st157"
     inkscape:label="DHCR24_LEFTY1 f"
     inkscape:connector-curvature="0"
     id="F_DHCR24_LEFTY1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22309995"
     d="m 768.2,457.11855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -35,0.2 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 45.6,8.8 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
     class="st157"
     inkscape:label="ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2 f"
     inkscape:connector-curvature="0"
     id="F_ACACB_PRKAG2_PRKAB2_ACACA_PRKAA2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22309995"
     d="m 779,432.11855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -16,-11.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st157"
     inkscape:label="FASN_1 f"
     inkscape:connector-curvature="0"
     id="F_FASN_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 864.2,457.11855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 11.6,9.6 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
     class="st22"
     inkscape:connector-curvature="0"
     id="F_MCAT_FASN" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1093.3,432.21855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -11.1,-11.5 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -51.2,-1.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 25,0.2 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -63.6,1.2 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st22"
     inkscape:label="OLAH_FASN f"
     inkscape:connector-curvature="0"
     id="F_OLAH_FASN" /><path
     style="fill:none;stroke:#000000;stroke-width:2.2256"
     d="m 975.2,225.31855 c -6,1.1 -5.5,9 -5.5,9 m -30.5,-9 c -6,1.1 -5.5,9 -5.5,9 m -50,-9 c -6,1.1 -5.5,9 -5.5,9 m -39.5,-9 c -6,1.1 -5.5,9 -5.5,9 m 98.6,-9.1 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -71.9,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m 16.6,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -67.6,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m 85.1,10.6 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -73.5,9.4 c 6,-1 4.5,-9.4 4.5,-9.4 m 15.7,9.9 c -6,1.1 -5.5,9 -5.5,9 m -37,-9.1 c -6,1.1 -5.5,9 -5.5,9 m 99.1,-8.8 c -6,1.1 -5.5,9 -5.5,9 m 73.4,-9.2 -174.7,-0.1"
     class="st160"
     inkscape:label="ATIC_2"
     inkscape:connector-curvature="0"
     id="R_ATIC_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 981.4,227.31855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -46.6,-11.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -26.4,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -21,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -21.8,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -20.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st22"
     inkscape:label="ATIC_2 f"
     inkscape:connector-curvature="0"
     id="F_ATIC_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.06660008"
     d="m 926.5,278.81855 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -22.6,8.2 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -25.6,8.2 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -28.6,8.5 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -27.1,8.5 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m 56.9,8.8 c -6,1.1 -5.5,9.2 -5.5,9.2 m -12.5,-9.2 c -6,1.1 -5.5,9.2 -5.5,9.2 m -14,-9.7 c -6,1.1 -5.5,9.2 -5.5,9.2 m -15.5,-9.2 c -6,1.1 -5.5,9.2 -5.5,9.2 m -11,-9.5 c -6,1.1 -5.5,9.2 -5.5,9.2 m -31.5,-9.3 148.9,1.2 m -134.4,-1.1 c -6,1.1 -5.5,9.2 -5.5,9.2 m 2.5,-8.7 c 6.1,-0.9 4.6,-8.5 4.6,-8.5 m -16.1,-40.9 c 0,49.6 0,49.6 0,49.6"
     class="st161"
     inkscape:label="UMPS_2"
     inkscape:connector-curvature="0"
     id="R_UMPS_2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.7335"
     d="m 1087.7,225.31855 -51.1,-0.3 m 13,0 c -6,0.8 -5.5,6.9 -5.5,6.9 m 12.9,-7.1 c 6,-1 4.5,-9.4 4.5,-9.4 m -18.9,9.8 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m 27.3,10.2 c 5.9,-1.1 4.4,-10.2 4.4,-10.2 m -10.4,10 c -6,0.8 -5.5,6.9 -5.5,6.9"
     class="st162"
     inkscape:connector-curvature="0"
     id="R_TNRC6B_ADSL_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1086.5,227.21855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -9.3,-11 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -17.3,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -14.2,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st22"
     inkscape:connector-curvature="0"
     id="F_TNRC6B_ADSL_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1703"
     class="st17 st18"
     x="1059.1674"
     y="207.14964">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1256.9,272.21855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -8.6,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st32"
     inkscape:label="GUK1_1 f"
     inkscape:connector-curvature="0"
     id="F_GUK1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1234.2,272.11855 c -6.9,-2 -6.9,-2 -6.9,-2 l 6.8,-2.4 -1.7,2.2 1.8,2.2 z m 3.6,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st32"
     inkscape:label="GUK1_1 b"
     inkscape:connector-curvature="0"
     id="B_GUK1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1321.7,270.71855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -7.7,8.8 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st32"
     inkscape:label="RRM2B_TXN_RRM1_RRM2B_1 f"
     inkscape:connector-curvature="0"
     id="F_RRM2B_TXN_RRM1_RRM2B_1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1708"
     class="st17 st18"
     x="1379.2269"
     y="295.87714">ADP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1710"
     class="st17 st18"
     x="1397.4281"
     y="296.41336">ATP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.92519999"
     d="m 1410.2,269.91855 c -24.9,0 -24.9,0 -24.9,0 m 16.5,9.5 c 2.4,-5.9 -3.6,-9.5 -3.6,-9.5 m -2.6,0.1 c -5,0.9 -4.4,9.3 -4.4,9.3"
     class="st148"
     inkscape:label="GUK1_2"
     inkscape:connector-curvature="0"
     id="R_GUK1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1409.9,272.31855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -8.5,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st32"
     inkscape:label="GUK1_2 f"
     inkscape:connector-curvature="0"
     id="F_GUK1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1386,271.61855 c -6.9,-2 -6.9,-2 -6.9,-2 l 6.8,-2.4 -1.7,2.2 1.8,2.2 z m 3.5,7.4 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st32"
     inkscape:label="GUK1_2 b"
     inkscape:connector-curvature="0"
     id="B_GUK1_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1715"
     class="st15 st16"
     x="1420.6156"
     y="273.48557">dGMP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.68470001"
     d="m 1156.6,213.31855 c -2.4,6.7 3.6,10.9 3.6,10.9 m 15.7,0.2 c -26.9,0 -26.9,0 -26.9,0 m 19.4,-11.1 c 2.4,6.7 -3.6,10.9 -3.6,10.9"
     class="st163"
     inkscape:label="AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1"
     inkscape:connector-curvature="0"
     id="R_AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1152.2,221.91855 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z m 1.9,-8.8 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st32"
     inkscape:label="AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1 f"
     inkscape:connector-curvature="0"
     id="F_AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1175.9,222.21855 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z m -8.6,-9.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st32"
     inkscape:label="AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1 b"
     inkscape:connector-curvature="0"
     id="B_AK2_TAF9_AK1_AK7_AK3_AK5_AKD1_AK4_AK8_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1238.3,226.01855 c 6.9,-2 6.9,-2 6.9,-2 l -6.8,-2.4 1.7,2.2 -1.8,2.2 z m -8.5,8.6 c 2,4.9 2,4.9 2,4.9 l 1.3,-5.6 -1.6,1.7 -1.7,-1 z"
     class="st32"
     inkscape:label="RRM2B_TXN_RRM1_RRM2B_2 f"
     inkscape:connector-curvature="0"
     id="F_RRM2B_TXN_RRM1_RRM2B_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 937.8,280.91855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -8.4,-10.3 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -18,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -21,-0.9 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -24,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -22.5,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -39,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st22"
     inkscape:label="UMPS_2 F"
     inkscape:connector-curvature="0"
     id="F_UMPS_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.48839998"
     d="m 965.8,316.01855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2,-7.4 -2.1,1.9 -2.1,-1.8 z m 12.7,-5.1 c 4.3,-1.4 4.3,-1.4 4.3,-1.4 l -4.4,-1 1.1,1.1 -1,1.3 z"
     class="st164"
     inkscape:label="CMPK2_CMPK1_1 f"
     inkscape:connector-curvature="0"
     id="F_CMPK2_CMPK1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.48839998"
     d="m 970,295.11855 c -2.2,-7.3 -2.2,-7.3 -2.2,-7.3 l -2,7.4 2.1,-1.9 2.1,1.8 z m 8.5,4.8 c 4.3,-1.4 4.3,-1.4 4.3,-1.4 l -4.4,-1 1.1,1.1 -1,1.3 z"
     class="st164"
     inkscape:label="CMPK2_CMPK1_1 b"
     inkscape:connector-curvature="0"
     id="B_CMPK2_CMPK1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.31130004"
     d="m 933.3,323.31855 c -1.9,-4.3 -1.9,-4.3 -1.9,-4.3 l -1.4,4.4 1.6,-1.2 1.7,1.1 z m -11,11.6 c -7.2,-2.4 -7.2,-2.4 -7.2,-2.4 l 7.4,-1.9 -1.9,2.1 1.7,2.2 z"
     class="st165"
     inkscape:label="RRM2B_TXN_RRM1_RRM2_1 f"
     inkscape:connector-curvature="0"
     id="F_RRM2B_TXN_RRM1_RRM2_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.31130004"
     d="m 836,334.81855 c -7.2,-2.4 -7.2,-2.4 -7.2,-2.4 l 7.4,-1.9 -1.9,2.1 1.7,2.2 z m 8.7,-11.2 c -1.9,-4.3 -1.9,-4.3 -1.9,-4.3 l -1.4,4.4 1.6,-1.2 1.7,1.1 z"
     class="st165"
     inkscape:label="CMPK1_DTYMK f"
     inkscape:connector-curvature="0"
     id="F_CMPK1_DTYMK" /><path
     style="fill:none;stroke:#000000;stroke-width:2.31130004"
     d="m 859.9,334.81855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z m -6.8,-10.8 c 1.9,-4.3 1.9,-4.3 1.9,-4.3 l 1.4,4.4 -1.6,-1.2 -1.7,1.1 z"
     class="st165"
     inkscape:label="CMPK1_DTYMK b"
     inkscape:connector-curvature="0"
     id="B_CMPK1_DTYMK" /><path
     style="fill:none;stroke:#000000;stroke-width:2.31130004"
     d="m 731.1,335.41855 c -7.2,-2.4 -7.2,-2.4 -7.2,-2.4 l 7.4,-1.9 -1.9,2.1 1.7,2.2 z m 9.1,-12.4 c -1.7,-4.7 -1.7,-4.7 -1.7,-4.7 l -1.1,4.8 1.3,-1.3 1.5,1.2 z"
     class="st165"
     inkscape:label="TYMS "
     inkscape:connector-curvature="0"
     id="F_TYMS" /><path
     style="fill:none;stroke:#000000;stroke-width:2.31130004"
     d="m 770.6,330.81855 c 7.2,2.4 7.2,2.4 7.2,2.4 l -7.4,1.9 1.9,-2.1 -1.7,-2.2 z m -4.7,-8.4 c -1.9,-5.3 -1.9,-5.3 -1.9,-5.3 l -1.8,5.3 1.8,-1.3 1.9,1.3 z"
     class="st165"
     inkscape:label="TYMS b"
     inkscape:connector-curvature="0"
     id="B_TYMS" /><path
     style="fill:none;stroke:#000000;stroke-width:1.82930005"
     d="m 995.7,334.41855 c -7.4,-1.9 -7.4,-1.9 -7.4,-1.9 l 7.2,-2.4 -1.8,2.2 2,2.1 z m 3.8,6 c 1.6,4.7 1.6,4.7 1.6,4.7 l 2.4,-4.6 -2.1,1.1 -1.9,-1.2 z"
     class="st109"
     inkscape:label="NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3 f"
     inkscape:connector-curvature="0"
     id="F_NME2_NME3_NME4_NME5_NME2P1_NME7_NME6_NME1_NME2_3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1093.9,325.01855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m 9.7,9.9 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
     class="st73"
     inkscape:label="CTPS2_GATM_CTPS1 f"
     inkscape:connector-curvature="0"
     id="F_CTPS2_GATM_CTPS1" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1731"
     class="st17 st18"
     x="1236.1302"
     y="316.99045">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1733"
     class="st17 st18"
     x="1216.7562"
     y="317.36545">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1229.5,324.71855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m -7,5.6 c -7.4,1.9 -7.4,1.9 -7.4,1.9 l 7.2,2.4 -1.8,-2.2 2,-2.1 z"
     class="st73"
     inkscape:label="CMPK2_CMPK1_2 b"
     inkscape:connector-curvature="0"
     id="B_CMPK2_CMPK1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1246.1,335.71855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -3.6,-10.9 c -1.1,-5.1 -1.1,-5.1 -1.1,-5.1 l -1.7,5 1.5,-1.2 1.3,1.3 z"
     class="st22"
     inkscape:label="CMPK2_CMPK1_2 f"
     inkscape:connector-curvature="0"
     id="F_CMPK2_CMPK1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:1.82930005"
     d="m 1218.5,332.61855 28.3,0.4 m -18.4,-9.2 c -2.2,5.6 3.9,8.9 3.9,8.9 m 4.8,0 c 5,-0.9 4,-8.9 4,-8.9"
     class="st109"
     inkscape:label="CMPK2_CMPK1_2"
     inkscape:connector-curvature="0"
     id="R_CMPK2_CMPK1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.31130004"
     d="m 1196.6,360.01855 c 2.4,7.2 2.4,7.2 2.4,7.2 l 1.9,-7.4 -2.1,1.9 -2.2,-1.7 z m -6.1,-7.6 c -4.6,1 -4.6,1 -4.6,1 l 2.7,-3.7 0,1.9 1.9,0.8 z"
     class="st165"
     inkscape:connector-curvature="0"
     id="F_RRM2B_TXN_RRM1_RRM2_2" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1739"
     class="st15 st16"
     x="1258.7123"
     y="382.35764">dCMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1741"
     class="st17 st18"
     x="1236.1302"
     y="361.80984">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1743"
     class="st17 st18"
     x="1216.7562"
     y="362.36545">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1229.5,369.71855 c -1.6,-6.1 -1.6,-6.1 -1.6,-6.1 l -1.3,6.2 1.4,-1.6 1.5,1.5 z m -7,5.6 c -7.4,1.9 -7.4,1.9 -7.4,1.9 l 7.2,2.4 -1.8,-2.2 2,-2.1 z"
     class="st73"
     inkscape:label="CMPK2_CMPK1_3 b"
     inkscape:connector-curvature="0"
     id="B_CMPK2_CMPK1_3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1246.1,380.71855 c 7.2,-2.5 7.2,-2.5 7.2,-2.5 l -7.4,-1.8 1.9,2.1 -1.7,2.2 z m -3.6,-10.9 c -1.1,-5.1 -1.1,-5.1 -1.1,-5.1 l -1.7,5 1.5,-1.2 1.3,1.3 z"
     class="st22"
     inkscape:label="CMPK2_CMPK1_3 f"
     inkscape:connector-curvature="0"
     id="F_CMPK2_CMPK1_3" /><path
     style="fill:none;stroke:#000000;stroke-width:1.82930005"
     d="m 1218.5,377.61855 28.3,0.4 m -18.4,-9.2 c -2.2,5.6 3.9,8.9 3.9,8.9 m 4.8,0 c 5,-0.9 4,-8.9 4,-8.9"
     class="st109"
     inkscape:label="CMPK2_CMPK1_3"
     inkscape:connector-curvature="0"
     id="R_CMPK2_CMPK1_3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 236.8,382.21855 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z m -52.2,-23.9 c -6.2,2.5 -6.2,2.5 -6.2,2.5 l 6.5,1.5 -1.7,-1.8 1.4,-2.2 z"
     class="st73"
     inkscape:label="MTHFD1_3 f"
     inkscape:connector-curvature="0"
     id="F_MTHFD1_3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 206.6,426.41855 c -6.2,2.5 -6.2,2.5 -6.2,2.5 l 6.5,1.5 -1.7,-1.8 1.4,-2.2 z m 31.7,-24 c 7,-1.3 7,-1.3 7,-1.3 l -6.9,-1.9 1.7,1.7 -1.8,1.5 z"
     class="st73"
     inkscape:label="MTHFD1_3 b"
     inkscape:connector-curvature="0"
     id="B_MTHFD1_3" /><text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1750"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="301.1604"
     y="383.42343">H</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text1752"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="307.39139"
     y="385.42346">2</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1754"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="310.4798"
     y="383.42337">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 290,301.91855 c 1.6,-5.3 17.5,-4.5 17.5,-4.5 m -2.3,19.7 c -9.8,2.5 -15.9,-3.8 -15.9,-3.8 m -0.3,11.1 0.2,-34.2"
     class="st79"
     inkscape:label="MTHFD2_2"
     inkscape:connector-curvature="0"
     id="R_MTHFD2_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 287,292.01855 c 2.3,-6.3 2.3,-6.3 2.3,-6.3 l 1.6,6.5 -1.9,-1.7 -2,1.5 z m 15.6,3.3 c 7,1.6 7,1.6 7,1.6 l -6.9,1.6 1.7,-1.6 -1.8,-1.6 z"
     class="st73"
     inkscape:label="MTHFD2_2 f"
     inkscape:connector-curvature="0"
     id="F_MTHFD2_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 301.3,316.11855 c 7,1.6 7,1.6 7,1.6 l -6.9,1.6 1.7,-1.6 -1.8,-1.6 z m -10.5,6.6 c -2,7.3 -2,7.3 -2,7.3 l -2.3,-7.3 2.2,1.8 2.1,-1.8 z"
     class="st73"
     inkscape:label="MTHFD2_2 b"
     inkscape:connector-curvature="0"
     id="B_MTHFD2_2" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1759"
     class="st17 st18"
     transform="matrix(0.99999044,0.00437222,-0.00437222,0.99999044,0,0)"
     x="311.63144"
     y="319.94809">NADH</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1761"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="307.66241"
     y="303.30228">NAD</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 402.2,547.01855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 34,12.7 c 6.3,-2.3 6.3,-2.3 6.3,-2.3 l -6.5,-1.6 1.7,1.9 -1.5,2 z"
     class="st30"
     inkscape:label="PEPCK f"
     inkscape:connector-curvature="0"
     id="F_PEPCK" /><path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 268.8,649.41855 c 2.3,7.2 2.3,7.2 2.3,7.2 l 2,-7.3 -2.1,1.9 -2.2,-1.8 z m -11.1,-9.3 c -5.1,1.5 -5.1,1.5 -5.1,1.5 l 5.5,1.8 -1.5,-1.7 1.1,-1.6 z"
     class="st45"
     inkscape:label="FH_3 f"
     inkscape:connector-curvature="0"
     id="F_FH_3" /><path
     style="fill:none;stroke:#000000;stroke-width:2.23090005"
     d="m 1444.3,1060.1186 c 2.4,-5.7 2.4,-5.7 2.4,-5.7 l 2,5.8 -2.1,-1.5 -2.3,1.4 z m 57.4,10.4 c 6.6,3 6.6,3 6.6,3 l -7.1,1.4 2,-2 -1.5,-2.4 z"
     class="st37"
     inkscape:connector-curvature="0"
     id="B_SLC25A5_SLC25A4_SLC25A6" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1050.3,691.11855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z m 11.6,-3.8 c 4.7,1.4 4.7,1.4 4.7,1.4 l -5.1,1.5 1.4,-1.4 -1,-1.5 z"
     class="st14"
     inkscape:label="TransportGlu f"
     inkscape:connector-curvature="0"
     id="F_TransportGlu" /><path
     style="fill:none;stroke:#000000;stroke-width:2.15549994"
     d="m 954.1,690.71855 c 2.2,7.1 2.2,7.1 2.2,7.1 l 2.2,-7.1 -2.2,1.8 -2.2,-1.8 z m 12.5,-2.2 c 4.7,1.3 4.7,1.3 4.7,1.3 l -5.1,1.4 1.4,-1.4 -1,-1.3 z"
     class="st166"
     inkscape:label="TransportGln f"
     inkscape:connector-curvature="0"
     id="F_TransportGln" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 956,636.91855 c 2.2,7.3 2.2,7.3 2.2,7.3 l 2.2,-7.3 -2.2,1.8 -2.2,-1.8 z m 77.1,-13.1 c -1.4,4.7 -1.4,4.7 -1.4,4.7 l -1.5,-5.1 1.4,1.4 1.5,-1 z m -48,0.4 c -1.4,4.7 -1.4,4.7 -1.4,4.7 l -1.5,-5.1 1.4,1.4 1.5,-1 z"
     class="st14"
     inkscape:label="GS f"
     inkscape:connector-curvature="0"
     id="F_GS" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1022.5,652.11855 c 6.9,2.1 6.9,2.1 6.9,2.1 l -6.9,2.3 1.7,-2.2 -1.7,-2.2 z m -14.8,-6.7 c 1.4,-4.7 1.4,-4.7 1.4,-4.7 l 1.5,5.1 -1.4,-1.4 -1.5,1 z"
     class="st32"
     inkscape:label="GLS2 f"
     inkscape:connector-curvature="0"
     id="F_GLS2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1029.4,709.51855 c 6.9,-2.1 6.9,-2.1 6.9,-2.1 l -6.9,-2.3 1.7,2.2 -1.7,2.2 z m -17.8,-8.9 c 0.9,-4.9 0.9,-4.9 0.9,-4.9 l -3.6,3.9 1.9,-0.6 0.8,1.6 z"
     class="st32"
     inkscape:label="GLS f"
     inkscape:connector-curvature="0"
     id="F_GLS" /><path
     style="fill:none;stroke:#000000;stroke-width:1.99090004"
     d="m 1270.4,787.81855 c 2.8,-7.3 -3.1,-12.1 -3.1,-12.1 m 49.7,12.1 c 2.8,-7.3 -3.1,-12.1 -3.1,-12.1 m -17.1,12.1 c 2.8,-7.3 -3.1,-12.1 -3.1,-12.1 m -53.7,0.4 c -5.3,0.6 -5,7.6 -5,7.6 m 89.5,-8 c -99.3,0 -99.3,0 -99.3,0 m 29.8,0.4 c -5.3,0.6 -5,7.6 -5,7.6"
     class="st167"
     inkscape:label="CPS1"
     inkscape:connector-curvature="0"
     id="R_CPS1" /><text
     style="font-size:16.00031662px;font-family:Calibri-Bold"
     id="text1772"
     class="st15 st16"
     transform="matrix(0.99998015,0.00630041,-0.00630041,0.99998015,0,0)"
     x="1205.1744"
     y="771.00928">CP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 1351.5,622.81855 c -6.9,-1.7 -6.9,-1.7 -6.9,-1.7 l 5.5,4.6 -0.8,-2.2 2.2,-0.7 z m 11,-3.3 c -1.8,-7.4 -1.8,-7.4 -1.8,-7.4 l -2.5,7.2 2.2,-1.7 2.1,1.9 z"
     class="st73"
     inkscape:label="ALDH4A1_2 f"
     inkscape:connector-curvature="0"
     id="F_ALDH4A1_2" /><text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1775"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1386.1115"
     y="542.35461">Gly</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1777"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="1404.1106"
     y="542.55579">GA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 952,862.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -12.1,9.3 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z"
     class="st22"
     inkscape:label="CA5B_CA5A f"
     inkscape:connector-curvature="0"
     id="F_CA5B_CA5A" /><text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1780"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="665.34772"
     y="1031.6384">H</text>
<text
     style="font-size:6.09346962px;font-family:Calibri"
     id="text1782"
     class="st17 st26"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="671.57819"
     y="1033.6384">2</text>
<text
     style="font-size:9.99962234px;font-family:Calibri"
     id="text1784"
     class="st17 st18"
     transform="matrix(0.9999378,-0.011153,0.011153,0.9999378,0,0)"
     x="674.66699"
     y="1031.6384">O</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.29760003"
     d="m 707.7,1012.8186 c 2.9,-9.7 -3.2,-16.00005 -3.2,-16.00005 m -47.9,0.2 61.6,-0.1 m -33,15.90005 c 2.9,-9.7 -3.2,-16.00005 -3.2,-16.00005 m -14.3,0.3 c -5.3,1.4 -5.1,17.30005 -5.1,17.30005"
     class="st79"
     inkscape:label="SHMT1_2 "
     inkscape:connector-curvature="0"
     id="R_SHMT1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.09949994"
     d="m 707,1008.9186 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z m 10.5,-9.70005 c 6.3,-2.3 6.3,-2.3 6.3,-2.3 l -6.5,-1.7 1.7,1.9 -1.5,2.1 z m -33,9.70005 c 1.3,7 1.3,7 1.3,7 l 1.9,-6.9 -1.7,1.7 -1.5,-1.8 z"
     class="st73"
     inkscape:label="SHMT1_2 f"
     inkscape:connector-curvature="0"
     id="F_SHMT1_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1442.5,809.71855 c -7.2,2.4 -7.2,2.4 -7.2,2.4 l 7.4,1.9 -1.9,-2.1 1.7,-2.2 z"
     class="st22"
     inkscape:label="TransportFolate f"
     inkscape:connector-curvature="0"
     id="path1985" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1489.5,814.81855 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
     class="st22"
     inkscape:label="SLC16A3_SLC16A1_SLC16A5_2 f"
     inkscape:connector-curvature="0"
     id="F_SLC16A3_SLC16A1_SLC16A5_2" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1490.3,756.31855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st22"
     inkscape:transform-center-y="-3.0492074"
     inkscape:transform-center-x="0.87100132"
     inkscape:label="Transport_serine b"
     inkscape:connector-curvature="0"
     id="B_Transport_serine" /><text
     style="font-size:10.00011921px;font-family:Calibri"
     id="text1791"
     class="st17 st18"
     transform="matrix(0.99998813,0.00487302,-0.00487302,0.99998813,0,0)"
     x="835.31476"
     y="1042.428">formate+ATP</text>
<text
     style="font-size:10.00011921px;font-family:Calibri"
     id="text1793"
     class="st17 st18"
     transform="matrix(0.99998813,0.00487302,-0.00487302,0.99998813,0,0)"
     x="891.94086"
     y="1042.8938">ADP+Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.80649996"
     d="m 1525.5,392.51855 c -5.4,-1.7 -4.9,-14 -4.9,-14 m 10.8,14.3 c 5.5,-1.1 4.1,-10.6 4.1,-10.6 m 9,10.6 -33.9,-0.3"
     class="st116"
     inkscape:label="LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1"
     inkscape:connector-curvature="0"
     id="R_LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1543.5,394.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -6.5,-11.3 c -1.7,-5.2 -1.7,-5.2 -1.7,-5.2 l -1.4,5.3 1.5,-1.4 1.6,1.3 z"
     class="st22"
     inkscape:label="LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1 f"
     inkscape:connector-curvature="0"
     id="F_LHPP_PPA2_PRUNE_EIF4A2_NAV2_PPA1_1" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1543.5,348.31855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -6.5,-11.3 c -1.7,-5.2 -1.7,-5.2 -1.7,-5.2 l -1.4,5.3 1.5,-1.4 1.6,1.3 z"
     class="st22"
     inkscape:label="CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13 f"
     inkscape:connector-curvature="0"
     id="F_CA12_CA2_CA9_CA14_CA1_CA3_CA4_CA7_CA13" /><path
     style="fill:none;stroke:#000000;stroke-width:9.22049999;stroke-linecap:round;stroke-linejoin:round;stroke-miterlimit:2"
     inkscape:connector-curvature="0"
     d="m 290.9,65.418554 1141.8,0 c 111.4,0 201.6,90.299996 201.6,201.599996 l 0,777.20005 c 0,111.4 -90.3,201.6 -201.6,201.6 l -1141.8,0 c -111.4,0 -201.6,-90.3 -201.6,-201.6 l 0,-777.10005 c 0,-111.4 90.3,-201.699996 201.6,-201.699996 z"
     class="st168"
     id="rect3173" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1799"
     class="st17 st18"
     x="1582.0922"
     y="894.75116">AMP+PPi</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1801"
     class="st17 st18"
     x="1583.309"
     y="884.0647">ATP+CoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.92519999"
     d="m 1565.4,888.01855 c 0.9,5 9.3,4.4 9.3,4.4 m 4.5,-10.4 c -8.6,-2.3 -13.9,3.4 -13.9,3.4 m -0.1,-11.9 c 0,24.9 0,24.9 0,24.9"
     class="st148"
     inkscape:label="palmitateActivation"
     inkscape:connector-curvature="0"
     id="R_palmitateActivation" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1567.3,897.51855 c -2,6.9 -2,6.9 -2,6.9 l -2.4,-6.8 2.2,1.7 2.2,-1.8 z m 7.4,-3.5 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
     class="st32"
     inkscape:label="palmitateActivation f"
     inkscape:connector-curvature="0"
     id="F_palmitateActivation" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1805"
     class="st15 st16"
     x="1547.4984"
     y="863.4964">Palm</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1807"
     class="st15 st16"
     x="1537.4193"
     y="918.66138">PalmCoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1809"
     class="st17 st18"
     x="1582.8129"
     y="953.61157">CoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1811"
     class="st17 st18"
     x="1582.9476"
     y="942.5647">carnitine</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.92519999"
     d="m 1565.2,932.01855 c 0,24.9 0,24.9 0,24.9 m 9.6,-16.5 c -5.9,-2.4 -9.5,3.6 -9.5,3.6 m 0.1,2.5 c 0.9,5 9.3,4.4 9.3,4.4"
     class="st148"
     inkscape:label="carnitineAcylTransferaseI"
     inkscape:connector-curvature="0"
     id="R_carnitineAcylTransferaseI" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1567.3,933.41855 c -2,-6.9 -2,-6.9 -2,-6.9 l -2.4,6.8 2.2,-1.7 2.2,1.8 z m 7.4,8.6 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
     class="st32"
     inkscape:label="carnitineAcylTransferaseI b"
     inkscape:connector-curvature="0"
     id="B_carnitineAcylTransferaseI" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1567.3,956.01855 c -2,6.9 -2,6.9 -2,6.9 l -2.4,-6.8 2.2,1.7 2.2,-1.8 z m 7.4,-3.5 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
     class="st32"
     inkscape:label="carnitineAcylTransferaseI f"
     inkscape:connector-curvature="0"
     id="F_carnitineAcylTransferaseI" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1816"
     class="st15 st16"
     x="1509.2845"
     y="977.52167">PalmCarnitine</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.56680012"
     d="m 1477.7,972.41855 c 5.3,-1.5 4.6,-15.8 4.6,-15.8 m -29,0 c -2.5,10 3.7,16.2 3.7,16.2 m -18.4,0.1 c 58.9,0 58.9,0 58.9,0"
     class="st169"
     inkscape:label="translocase"
     inkscape:connector-curvature="0"
     id="R_translocase" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1483.8,956.91855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -43.4,14 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z"
     class="st32"
     inkscape:label="translocase f"
     inkscape:connector-curvature="0"
     id="F_translocase" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1454.7,956.91855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 40.6,13.9 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z"
     class="st32"
     inkscape:connector-curvature="0"
     id="path3243" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1821"
     class="st17 st18"
     x="1476.4476"
     y="948.5647">carnitine</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1823"
     class="st17 st18"
     x="1425.4476"
     y="948.5647">carnitine</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1825"
     class="st15 st16"
     x="1333.4193"
     y="977.16138">PalmCarnitine</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1315.8,962.01855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 3.6,7.4 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z"
     class="st32"
     inkscape:connector-curvature="0"
     id="path3291" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1305.3,962.01855 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m -8.5,7.4 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z"
     class="st32"
     inkscape:label="carnitineAcylTransferaseII f"
     inkscape:connector-curvature="0"
     id="F_carnitineAcylTransferaseII" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1309.9,971.31855 c 5,-0.9 4.4,-9.3 4.4,-9.3 m -10.6,-0.1 c -2.4,5.9 3.6,9.5 3.6,9.5 m -12,0 c 24.9,0 24.9,0 24.9,0"
     class="st32"
     inkscape:label="carnitineAcylTransferaseII "
     inkscape:connector-curvature="0"
     id="R_carnitineAcylTransferaseII" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1830"
     class="st17 st18"
     x="1311.5248"
     y="953.61157">CoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1832"
     class="st17 st18"
     x="1271.8422"
     y="952.50116">carnitine</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1834"
     class="st15 st16"
     x="1222.6273"
     y="976.7356">PalmCoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1836"
     class="st17 st18"
     x="1206.2504"
     y="990.83716">7 CoA</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1838"
     class="st17 st18"
     x="1171.7504"
     y="990.83716">7 NAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1840"
     class="st17 st18"
     x="1141.7504"
     y="990.83716">7 FAD</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1842"
     class="st17 st18"
     x="1110.2504"
     y="990.83716">7 H</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1844"
     class="st17 st26"
     x="1123.809"
     y="992.83716">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1846"
     class="st17 st18"
     x="1126.8978"
     y="990.83716">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1848"
     class="st17 st18"
     x="1165.7504"
     y="951.83716">7 NADH</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1850"
     class="st17 st18"
     x="1128.2504"
     y="951.83716">7 FADH</text>
<text
     style="font-size:6.09369993px;font-family:Calibri"
     id="text1852"
     class="st17 st26"
     x="1157.7816"
     y="953.83716">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1854"
     class="st17 st18"
     x="1105.7504"
     y="951.83716">7 H</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.93280005"
     d="m 1120.2,971.91855 c -5.6,-1.9 -4.1,-12.1 -4.1,-12.1 m 35.6,12.1 c -5.6,-1.9 -4.1,-12.1 -4.1,-12.1 m 35.6,12.1 c -5.6,-1.9 -4.1,-12.1 -4.1,-12.1 m -58.4,11.7 c 5.6,1.5 5.5,11.8 5.5,11.8 m 24.5,-11.8 c 5.6,1.5 5.5,11.8 5.5,11.8 m 29,-11.8 c 5.6,1.5 5.5,11.8 5.5,11.8 m 13.9,-12.1 c 5.6,1.5 5.5,11.8 5.5,11.8 m 10.1,-11.6 -112,0.1"
     class="st170"
     inkscape:label="betaOxidation "
     inkscape:connector-curvature="0"
     id="R_betaOxidation" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1109.3,969.41855 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z m 8.5,-8.8 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 31.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z m 31.5,0 c -2,-4.9 -2,-4.9 -2,-4.9 l -1.3,5.6 1.6,-1.7 1.7,1 z"
     class="st32"
     inkscape:label="betaOxidation f"
     inkscape:connector-curvature="0"
     id="F_betaOxidation" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1858"
     class="st15 st16"
     x="1042.6273"
     y="976.7356">8 AcCoA</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1567.3,874.91855 c -2,-6.9 -2,-6.9 -2,-6.9 l -2.4,6.8 2.2,-1.7 2.2,1.8 z m 7.4,8.6 c 4.9,-2 4.9,-2 4.9,-2 l -5.6,-1.3 1.7,1.6 -1,1.7 z"
     class="st32"
     inkscape:label="palmitateActivation b"
     inkscape:connector-curvature="0"
     id="B_palmitateActivation" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1861"
     class="st15 st16"
     x="1486.4927"
     y="427.78244">ATP</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1863"
     class="st15 st16"
     x="1554.2847"
     y="427.81766">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.80649996"
     d="m 1544.5,425.81855 -33.9,-0.3"
     class="st116"
     inkscape:label="ATPmaintenance "
     inkscape:connector-curvature="0"
     id="R_ATPmaintenance" /><path
     style="fill:none;stroke:#000000;stroke-width:2.5"
     d="m 1543.5,427.81855 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z"
     class="st22"
     inkscape:label="ATPmaintenancef"
     inkscape:connector-curvature="0"
     id="F_ATPmaintenance" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1867"
     class="st15 st38"
     x="259.638"
     y="851.84009">Pi</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1869"
     class="st15 st16"
     x="278.91238"
     y="912.47101">Orn</text>
<path
     style="fill:none;stroke:#000000;stroke-width:3.19709992"
     d="m 237.8,908.91855 c -6,-8.4 -6,-12.6 -6.6,-16.9 m 29,16.8 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 11.2,13.9 -60.2,-0.3"
     class="st171"
     inkscape:label="UniportOrnithine"
     inkscape:connector-curvature="0"
     id="R_UniportOrnithine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 267.4,895.31855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 l 0,0 z"
     class="st140"
     inkscape:label="UniportOrnithine f"
     inkscape:connector-curvature="0"
     id="F_UniportOrnithine" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1873"
     class="st15 st38"
     x="261.46759"
     y="887.15851">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1875"
     class="st15 st38"
     x="226.01099"
     y="888.6438">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1877"
     class="st15 st16"
     x="180.79909"
     y="912.72589">Orn</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1879"
     class="st15 st16"
     x="303.034"
     y="950.73657">Orn</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1881"
     class="st15 st16"
     x="170.7791"
     y="950.48169">Orn</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 283.9,934.31855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -50,2.4 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m -26.6,8.8 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
     class="st140"
     inkscape:connector-curvature="0"
     id="path3519" /><path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 218.4,948.01855 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 65.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -43.2,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 29.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
     class="st45"
     inkscape:label="CotraspArgOrnA"
     inkscape:connector-curvature="0"
     id="R_CotraspArgOrnA" /><path
     style="fill:none;stroke:#000000;stroke-width:2.35560012"
     d="m 214.4,936.71855 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 76.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -23.1,-15.5 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
     class="st46"
     inkscape:label="CotraspArgOrnA f"
     inkscape:connector-curvature="0"
     id="F_CotraspArgOrnA" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1886"
     class="st15 st38"
     x="259.9368"
     y="926.9231">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1888"
     class="st15 st38"
     x="226.01099"
     y="927.6438">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1890"
     class="st15 st38"
     x="199.5208"
     y="926.62427">Arg</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1892"
     class="st15 st38"
     x="273.05161"
     y="926.62427">Arg</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1894"
     class="st15 st16"
     x="300.10669"
     y="992.00116">Orn</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1896"
     class="st15 st16"
     x="176.7791"
     y="991.49146">Orn</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 289.9,974.81855 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -76.6,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z m 60.1,-11.2 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
     class="st140"
     inkscape:label="CotraspArgOrnB f"
     inkscape:connector-curvature="0"
     id="F_CotraspArgOrnB" /><path
     style="fill:none;stroke:#000000;stroke-width:3.13730001"
     d="m 227.1,988.41855 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 62.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -41.5,14 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 27.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
     class="st172"
     inkscape:label="CotraspArgOrnB"
     inkscape:connector-curvature="0"
     id="R_CotraspArgOrnB" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1900"
     class="st15 st38"
     x="265.9368"
     y="967.4231">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1902"
     class="st15 st38"
     x="232.01099"
     y="968.1438">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1904"
     class="st15 st38"
     x="205.5208"
     y="967.12427">Arg</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1906"
     class="st15 st38"
     x="279.05161"
     y="967.12427">Arg</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1908"
     class="st15 st16"
     x="303.034"
     y="1030.2366">Ci</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1910"
     class="st15 st16"
     x="182.74879"
     y="1032.5325">Ci</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 283.9,1013.8186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -50,2.4 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m -26.6,8.8 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
     class="st140"
     inkscape:label="CotraspArgCitrA b"
     inkscape:connector-curvature="0"
     id="B_CotraspArgCitrA" /><path
     style="fill:none;stroke:#000000;stroke-width:2.82299995"
     d="m 218.4,1027.5186 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 65.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -43.2,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7 m 29.1,12.5 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
     class="st45"
     inkscape:label="CotraspArgCitrA"
     inkscape:connector-curvature="0"
     id="R_CotraspArgCitrA" /><path
     style="fill:none;stroke:#000000;stroke-width:2.35560012"
     d="m 214.4,1016.2186 c -2.4,-5.9 -2.4,-5.9 -2.4,-5.9 l -2.3,6 2.3,-1.5 2.4,1.4 z m 76.1,13.1 c 7.2,-2.3 7.2,-2.3 7.2,-2.3 l -7.3,-2 1.9,2.1 -1.8,2.2 z m -23.1,-15.5 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
     class="st46"
     inkscape:label="CotraspArgCitrA f"
     inkscape:connector-curvature="0"
     id="F_CotraspArgCitrA" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1915"
     class="st15 st38"
     x="259.9368"
     y="1006.4231">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1917"
     class="st15 st38"
     x="226.01099"
     y="1007.1438">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1919"
     class="st15 st38"
     x="199.5208"
     y="1006.1243">Arg</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1921"
     class="st15 st38"
     x="273.05161"
     y="1006.1243">Arg</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 282.4,1048.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -76.6,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z m 60.1,-11.2 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
     class="st140"
     inkscape:label="CotraspArgCitrB f"
     inkscape:connector-curvature="0"
     id="F_CotraspArgCitrB" /><path
     style="fill:none;stroke:#000000;stroke-width:3.13730001"
     d="m 219.6,1061.9186 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 62.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -41.5,14 c -5.9,-8.2 -5.9,-12.4 -6.5,-16.5 m 27.1,16.4 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 26.7,13.9 -84.7,-0.2"
     class="st172"
     inkscape:label="CotraspArgCitrB"
     inkscape:connector-curvature="0"
     id="R_CotraspArgCitrB" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1925"
     class="st15 st38"
     x="258.4368"
     y="1040.9231">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1927"
     class="st15 st38"
     x="224.51099"
     y="1041.6438">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1929"
     class="st15 st38"
     x="198.0208"
     y="1040.6243">Arg</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1931"
     class="st15 st38"
     x="271.55161"
     y="1040.6243">Arg</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1933"
     class="st15 st16"
     x="292.57349"
     y="1066.5403">Ci</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1935"
     class="st15 st16"
     x="182.74879"
     y="1067.0325">Ci</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1937"
     class="st15 st16"
     x="289.01248"
     y="1101.4709">Arg</text>
<path
     style="fill:none;stroke:#000000;stroke-width:3.19709992"
     d="m 237.8,1097.9186 c -6,-8.4 -6,-12.6 -6.6,-16.9 m 29,16.8 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 11.2,13.9 -60.2,-0.3"
     class="st171"
     inkscape:label="UniportArginine"
     inkscape:connector-curvature="0"
     id="R_UniportArginine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 267.4,1084.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
     class="st140"
     inkscape:label="UniportArginine f"
     inkscape:connector-curvature="0"
     id="F_UniportArginine" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1941"
     class="st15 st38"
     x="261.46759"
     y="1076.1584">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1943"
     class="st15 st38"
     x="226.01099"
     y="1077.6438">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1945"
     class="st15 st16"
     x="180.79909"
     y="1101.7258">Arg</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1947"
     class="st15 st16"
     x="295.41238"
     y="1140.4709">Ci</text>
<path
     style="fill:none;stroke:#000000;stroke-width:3.19709992"
     d="m 246.8,1136.9186 c -6,-8.4 -6,-12.6 -6.6,-16.9 m 29,16.8 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m 11.2,13.9 -60.2,-0.3"
     class="st171"
     inkscape:label="UniportCitrulline"
     inkscape:connector-curvature="0"
     id="R_UniportCitrulline" /><path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 276.4,1123.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z m -51.1,11.2 c -2.4,0.8 -4.8,1.6 -7.2,2.4 2.5,0.6 4.9,1.3 7.4,1.9 -0.6,-0.7 -1.3,-1.4 -1.9,-2.1 0.6,-0.7 1.1,-1.4 1.7,-2.2 z"
     class="st140"
     inkscape:label="UniportCitrulline f"
     inkscape:connector-curvature="0"
     id="F_UniportCitrulline" /><text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1951"
     class="st15 st38"
     x="270.46759"
     y="1115.1584">H</text>
<text
     style="font-size:14px;font-family:Calibri-Bold"
     id="text1953"
     class="st15 st38"
     x="235.37189"
     y="1114.1194">H</text>
<text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1955"
     class="st15 st16"
     x="202.06329"
     y="1141.4475">Ci</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 275.3,1099.8186 c 2.4,-0.8 4.8,-1.6 7.2,-2.4 -2.5,-0.6 -4.9,-1.3 -7.4,-1.9 0.6,0.7 1.3,1.4 1.9,2.1 -0.6,0.8 -1.1,1.5 -1.7,2.2 z m -40.9,-15.5 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.6,0.5 1.4,1 2.2,1.5 z"
     class="st140"
     inkscape:label="UniportArginine b"
     inkscape:connector-curvature="0"
     id="B_UniportArginine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.32780004"
     d="m 243,1123.3186 c -0.6,-1.9 -1.3,-3.9 -1.9,-5.8 -0.9,1.9 -1.9,3.7 -2.8,5.6 0.8,-0.4 1.7,-0.9 2.5,-1.3 0.7,0.5 1.4,1 2.2,1.5 z m 41.3,15.5 c 2.4,-0.8 4.8,-1.6 7.2,-2.4 -2.5,-0.6 -4.9,-1.3 -7.4,-1.9 0.6,0.7 1.3,1.4 1.9,2.1 -0.6,0.8 -1.1,1.5 -1.7,2.2 z"
     class="st140"
     inkscape:label="UniportCitrulline b"
     inkscape:connector-curvature="0"
     id="B_UniportCitrulline" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22029996"
     d="m 1039.7789,1224.1775 0.3,50.4"
     class="st68"
     inkscape:label="DM_10formylTHFc"
     inkscape:connector-curvature="0"
     id="R_DM_10formylTHFc" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1960"
     class="st15 st16"
     x="984.76355"
     y="1218.4149">10-formylTHF</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 1037.8789,1273.7775 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
     class="st63"
     inkscape:label="DM_10formylTHFc f"
     inkscape:connector-curvature="0"
     id="F_DM_10formylTHFc" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1963"
     class="st15 st16"
     x="739.07251"
     y="1219.4495">carnitine</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 769.6,1234.7186 0,47.6"
     class="st63"
     inkscape:label="DM_Carnitine"
     inkscape:connector-curvature="0"
     id="R_DM_Carnitine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 769.8,1233.4186 2.2,1.8 -2.2,-7.2 -2.2,7.2 2.2,-1.8 z"
     class="st63"
     inkscape:label="DM_Carnitine f"
     inkscape:connector-curvature="0"
     id="F_DM_Carnitine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 1382.6,1269.2186 2.2,7.2 2.2,-7.2 -2.2,1.8 -2.2,-1.8 z"
     class="st63"
     inkscape:label="Palmitate_DM_COOP f"
     inkscape:connector-curvature="0"
     id="F_Palmitate_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 1384.7,1222.0186 0,47.6"
     class="st63"
     inkscape:label="Palmitate_DM_COOP"
     inkscape:connector-curvature="0"
     id="R_Palmitate_DM_COOP" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1969"
     class="st15 st16"
     x="1377.4066"
     y="1218.3489">Palm</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1305.8,1276.7186 -0.3,-48.1"
     class="st14"
     inkscape:label="Arginine_DM_COOP"
     inkscape:connector-curvature="0"
     id="R_Arginine_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 1267.8,1232.1186 2.2,-7.7 2.2,7.7 -2.2,-1.9 -2.2,1.9 z"
     class="st69"
     inkscape:label="Glutamate_DM_COOP b"
     inkscape:connector-curvature="0"
     id="B_Glutamate_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:3.16359997"
     d="m 643.6,1230.3186 2.2,-6.9 2.2,6.9 -2.2,-1.7 -2.2,1.7 z"
     class="st65"
     inkscape:label="Ex_NH3 b"
     inkscape:connector-curvature="0"
     id="B_Ex_NH3" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1974"
     class="st17 st18"
     x="1314.7279"
     y="204.19505">ATP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1976"
     class="st17 st18"
     x="1294.9379"
     y="204.31226">ADP</text>
<path
     style="fill:none;stroke:#000000;stroke-width:1.68470001"
     d="m 1308.1,213.31855 c -2.4,6.7 3.6,10.9 3.6,10.9 m 15.7,0.2 c -26.9,0 -26.9,0 -26.9,0 m 19.4,-11.1 c 2.4,6.7 -3.6,10.9 -3.6,10.9"
     class="st163"
     inkscape:label="AK"
     inkscape:connector-curvature="0"
     id="R_AK" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1303.7,221.91855 c -6.9,2 -6.9,2 -6.9,2 l 6.8,2.4 -1.7,-2.2 1.8,-2.2 z m 1.9,-8.8 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st32"
     inkscape:label="AK b"
     inkscape:connector-curvature="0"
     id="B_AK" /><path
     style="fill:none;stroke:#000000;stroke-width:2.44919991"
     d="m 1327.4,222.21855 c 6.9,2 6.9,2 6.9,2 l -6.8,2.4 1.7,-2.2 -1.8,-2.2 z m -8.6,-9.1 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
     class="st32"
     inkscape:label="AK f"
     inkscape:connector-curvature="0"
     id="F_AK" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text1981"
     class="st15 st16"
     x="1341.2035"
     y="225.97145">dAMP</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1983"
     class="st17 st18"
     x="422.99298"
     y="130.87186">H</text>
<text
     style="font-size:6.5px;font-family:Calibri"
     id="text1985"
     class="st17 st173"
     x="429.22339"
     y="132.87186">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1987"
     class="st17 st18"
     x="432.51788"
     y="130.87186">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1989"
     class="st17 st18"
     x="427.66238"
     y="118.75516">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 457.5,136.01855 0,-31.1 0,31.1 z m -0.4,-14.7 c -0.9,-5.5 -11.1,-5.3 -11.1,-5.3 m -3.6,11.8 c 8.8,2.9 14.6,-3.3 14.6,-3.3"
     class="st76"
     inkscape:label="G6PPer"
     inkscape:connector-curvature="0"
     id="R_G6PPer" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 447,117.71855 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z m 12.1,-10.7 c -1.7,-7.299996 -1.7,-7.299996 -1.7,-7.299996 l -1.7,7.299996 1.7,-1.8 1.7,1.8 z"
     class="st30"
     inkscape:label="F G6PPer"
     inkscape:connector-curvature="0"
     id="F_G6PPer" /><path
     style="fill:none;stroke:#000000;stroke-width:2.0948"
     d="m 457.9,245.51855 0,-31.1 0,31.1 z m -0.4,-14.8 c -0.9,-5.5 -11.1,-5.3 -11.1,-5.3 m -3.6,11.9 c 8.8,2.9 14.6,-3.3 14.6,-3.3"
     class="st76"
     inkscape:transform-center-y="-61.654422"
     inkscape:transform-center-x="138.9285"
     inkscape:connector-curvature="0"
     id="R_FBP" /><path
     style="fill:none;stroke:#000000;stroke-width:1.87170005"
     d="m 447.4,227.21855 c -4.9,-2 -4.9,-2 -4.9,-2 l 5.6,-1.3 -1.7,1.6 1,1.7 z m 12.1,-10.7 c -1.7,-7.3 -1.7,-7.3 -1.7,-7.3 l -1.7,7.3 1.7,-1.8 1.7,1.8 z"
     class="st30"
     inkscape:transform-center-y="-76.278967"
     inkscape:transform-center-x="138.06632"
     inkscape:label="FBP f"
     inkscape:connector-curvature="0"
     id="F_FBP" /><text
     style="font-size:10px;font-family:Calibri"
     id="text1995"
     class="st17 st18"
     x="424.16238"
     y="240.49146">H</text>
<text
     style="font-size:6.5px;font-family:Calibri"
     id="text1997"
     class="st17 st173"
     x="430.39288"
     y="242.49146">2</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text1999"
     class="st17 st18"
     x="433.6868"
     y="240.49146">O</text>
<text
     style="font-size:10px;font-family:Calibri"
     id="text2001"
     class="st17 st18"
     x="428.83179"
     y="228.37425">Pi</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.17810011"
     d="m 1405.8,1229.0186 0,47.6"
     class="st63"
     inkscape:label="Palmitate_UP_COOP"
     inkscape:connector-curvature="0"
     id="R_Palmitate_UP_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1403.7,1233.9186 2.1,-7.3 2.3,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="Palmitate_UP_COOP f"
     inkscape:connector-curvature="0"
     id="F_Palmitate_UP_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 767.6,1278.0186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
     class="st69"
     inkscape:label="DM_Carnitine b"
     inkscape:connector-curvature="0"
     id="B_DM_Carnitine" /><path
     style="fill:none;stroke:#000000;stroke-width:2.67510009"
     d="m 964.1,1232.4186 -2.2,-7.1 -2.2,7.1 2.2,-1.8 2.2,1.8 z"
     class="st64"
     inkscape:label="UptakeCitrate f"
     inkscape:connector-curvature="0"
     id="F_UptakeCitrate" /><path
     style="fill:none;stroke:#000000;stroke-width:2.67510009"
     d="m 962,1278.6186 0,-46.6"
     class="st64"
     inkscape:label="DM_Citrate"
     inkscape:connector-curvature="0"
     id="R_DM_Citrate" /><text
     style="font-size:16px;font-family:Calibri-Bold"
     id="text2008"
     class="st15 st16"
     x="952.39581"
     y="1218.1301">Cit</text>
<path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 959.6,1276.4186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
     class="st69"
     inkscape:label="UptakeCitrate b"
     inkscape:connector-curvature="0"
     id="B_UptakeCitrate" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1174.9998,1273.8805 -2.1,7.3 -2.3,-7.3 2.2,1.8 2.2,-1.8 z"
     class="st14"
     inkscape:label="Glucose_DM_COOP f"
     inkscape:connector-curvature="0"
     id="F_Glucose_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 1137.2,1273.5186 2.2,7.7 2.2,-7.7 -2.2,1.9 -2.2,-1.9 z"
     class="st69"
     inkscape:label="LactateL_DM_COOP f"
     inkscape:connector-curvature="0"
     id="F_DM_LactateL" /><path
     style="fill:none;stroke:#000000;stroke-width:2.22930002"
     d="m 1139.2,1223.4186 0,50.5"
     class="st69"
     inkscape:label="LactateL_DM_COOP"
     inkscape:connector-curvature="0"
     id="R_LactateL_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1231.89,1231.8186 2.2,-7.3 2.2,7.3 -2.2,-1.8 -2.2,1.8 z"
     class="st14"
     inkscape:label="Glutamine_DM_COOP b"
     inkscape:connector-curvature="0"
     id="B_Glutamine_DM_COOP" /><path
     style="fill:none;stroke:#000000;stroke-width:2.18210006"
     d="m 1233.89,1279.4186 0,-48"
     class="st14"
     inkscape:label="Glutamine_DM_COOP"
     inkscape:connector-curvature="0"
     id="R_Glutamine_DM_COOP" /><flowRoot
     xml:space="preserve"
     id="flowRoot5366"
     style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
     transform="translate(-20.6,18.418554)"><flowRegion
       id="flowRegion5368"><rect
         id="rect5370"
         width="1165.1471"
         height="77.465683"
         x="306.70087"
         y="-39.523308" /></flowRegion><flowPara
       id="flowPara5372" /></flowRoot><flowRoot
     xml:space="preserve"
     id="TitoloConfronto"
     style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
     inkscape:label="TitoloConfronto"
     transform="translate(-18.364224,56.426743)"><flowRegion
       id="flowRegion5376"><rect
         id="rect5378"
         width="1869.6877"
         height="68.569115"
         x="301.95807"
         y="-69.56102" /></flowRegion><flowPara
       id="TitleText"
       style="font-style:normal;font-variant:normal;font-weight:normal;font-stretch:normal;font-size:45px;font-family:sans-serif;-inkscape-font-specification:sans-serif">TITOLO: TITOLOTITOLO </flowPara></flowRoot><flowRoot
     xml:space="preserve"
     id="flowRoot5382"
     style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
     transform="translate(-16.64767,38.180207)"><flowRegion
       id="flowRegion5384"><rect
         id="rect5386"
         width="275.00043"
         height="149.79698"
         x="1681.3033"
         y="204.59315" /></flowRegion><flowPara
       id="flowPara5390"
       style="font-style:normal;font-variant:normal;font-weight:bold;font-stretch:normal;font-family:sans-serif;-inkscape-font-specification:'sans-serif Bold'">Fold Change</flowPara></flowRoot><flowRoot
     xml:space="preserve"
     id="FC_min"
     style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
     transform="translate(-8.622366,131.05768)"
     inkscape:label="FC_min"><flowRegion
       id="flowRegion5384-2"><rect
         id="rect5386-9"
         width="275.00043"
         height="149.79698"
         x="1681.3033"
         y="204.59315" /></flowRegion><flowPara
       id="Val_FC_min">min: </flowPara></flowRoot><flowRoot
     xml:space="preserve"
     id="FC_max"
     style="font-style:normal;font-weight:normal;font-size:35px;line-height:125%;font-family:sans-serif;letter-spacing:0px;word-spacing:0px;fill:#000000;fill-opacity:1;stroke:none;stroke-width:1px;stroke-linecap:butt;stroke-linejoin:miter;stroke-opacity:1"
     transform="translate(-17.492772,95.648076)"
     inkscape:label="FC_max"><flowRegion
       id="flowRegion5384-2-2"><rect
         id="rect5386-9-9"
         width="275.00043"
         height="149.79698"
         x="1681.3033"
         y="204.59315" /></flowRegion><flowPara
       id="Val_FC_max">max:</flowPara></flowRoot></svg>