# HG changeset patch
# User francesco_lapi
# Date 1732114358 0
# Node ID 14155e0bd8a5ed6efcc1da3c18e721fd48f946ed
# Parent 2ff3d05f321ac401f18bfe39431815bba3f554b9
Uploaded
diff -r 2ff3d05f321a -r 14155e0bd8a5 COBRAxy/local/svg metabolic maps/ENGRO2_no_legend_map.svg
--- a/COBRAxy/local/svg metabolic maps/ENGRO2_no_legend_map.svg Wed Nov 20 14:52:14 2024 +0000
+++ b/COBRAxy/local/svg metabolic maps/ENGRO2_no_legend_map.svg Wed Nov 20 14:52:38 2024 +0000
@@ -26,6 +26,25 @@
apply_with_weight="true"
only_selected="false"
uniform="false" />
+
+
+
+
-
-
-
- CySS
- CySS
- Ala
- Ala
-
-
-
- Ser
- Ser
- CySS
- CySS
-
-
-
-
+
+
+
+
+
- CySS
- CySS
- Leu
- Leu
-
-
+ id="path38" />
+
+
+ CySS
+ CySS
+ Leu
+ Leu
+
+
+
+
+
+
+ CySS
+ CySS
+ Ala
+ Ala
+
+
+
+
+
+ Ser
+ Ser
+ CySS
+ CySS
+
+
+
- CySS
- CySS
- Glu
-
- Glu
-
-
- Chol
-
-
+
+
+ CySS
+ CySS
+ Glu
+ Glu
+
+ Palm
+
+
+
+
+
+
+ Chol
+
+
+
+
+
+
+
+
+ Ala
+ Asp
+
+
-
-
-
- Palm
-
-
-
-
-
-
- Ala
+ d="m 2546.28,370.569 h 69 z"
+ fill="#2b0000"
+ id="path137" />
- Asp
+ id="path139" />
+
+
+
+
-
- Arg
+ id="path145" />
+
+ Arg
+
+
-
+
+
+ Glu
+
+
+ d="m 2618.28,547.569 h -75 z"
+ fill="#2b0000"
+ id="path160" />
+ id="path162" />
+
+
+
- Glu
- Ser
+ id="path167" />
+
+ Ser
+ Gly
+
+
- Gly
+ id="path178" />
+
+ Asn
+
+
+ id="path186" />
+
+
+
- Asn
+ id="path191" />
+
+ Tyr
+
+
- Tyr
+ id="path199" />
+
+ Cys
+
+
- Cys
+ id="path207" />
+
+ Pro
+
+
- Pro
- Gln
-
-
- His
-
-
- Leu
-
-
- Ile
-
-
- Lys
- Met
-
-
- Phe
-
-
- Thr
-
-
- Trp
-
-
-
- Val
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- BH4
-
-
-
- BH2
-
-
-
-
-
+ id="path215" />
+
+ Gln
+
+
+ His
+
+
+ Leu
+
+
+ Ile
+
+
+ Lys
+ Met
+
+
+ Phe
+
+
+ Thr
+
+
+ Trp
+
+
+
+ Val
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
O
+ id="tspan295">O
₂
-
-
-
-
-
-
-
-
-
-
-
- ₂
+
+
+
+
+ Pi
+
+
+
+ HO
+ ₂
+
+
+
+
-
- Pi
-
+
+ H
+
-
-
+ d="m 119.376,1205.15 9.773,2.74 -9.695,3.01 2.395,-2.91 z"
+ stroke="#000000"
+ stroke-width="2.32759" />
+
+
+
HO
+ id="text333">CO
₂
-
- ₂
+
+
+
+
-
-
-
- H
-
-
-
-
- CO
- ₂
-
-
-
-
-
-
-
-
-
- hcarn
-
-
-
-
- 4abut
-
-
-
-
- anth
-
-
-
+ d="m 58.346,1236.08 -9.0307,2.58 9.0307,2.58 -2.2575,-2.58 z"
+ stroke="#000000"
+ stroke-width="2.09785" />
+
+
+
+
+
+ hcarn
+
+
+
+
+ 4abut
+
+
+
+
+ anth
+
+
+
+
+
-
- Orn
- Arg
-
- HO
- ₂
-
-
- NH
- ₃
-
- Ci
- Gly
-
- SAH
-
-
-
- Creatine
- SAM
- GA
-
-
-
-
-
-
- CreatineP
- ATP
- ADP
-
+
+
+ Orn
+ Arg
+
+ HO
+ ₂
+
+
+ NH
+ ₃
+
+ Ci
+ Gly
+ GA
+
+
+
+
+
+
+ Creatine
+ SAM
+ SAH
+
+
+
+
+ CreatineP
+ ATP
+ ADP
+
+
+ Creatinine
+
+ H
+ ⁺
+
+ Pi
+
+
+
- Creatinine
-
- H
- ⁺
-
- Pi
-
+ d="m 345.896,1884.25 c -3.613,-12.95 4.687,-21.25 4.687,-21.25 z m 9.112,-20.97 c 7.164,1.66 6.571,18.97 6.571,18.97 z m -23.008,-0.01 46.363,-0.13 z"
+ fill="#2b0000"
+ id="path452" />
-
-
-
-
-
-
-
+ id="path454" />
+
+
+
+
+
+
+
+
+
+
+ DHF
+
+
-
-
-
- DHF
-
+ id="path468" />
-
+
+
+
+ NADP
+ ⁺
+
+
+ H
+
-
- NADP
- ⁺
-
-
- H
- ⁺
-
- ⁺
+
+ NADPH
+
+
+ Folate
+
+
+ NADPH
-
-
- Folate
-
+ id="path500" />
-
+
+
+
+
-
- NADP
- ⁺
-
-
- H
- ⁺
-
- NADP
+ ⁺
+
+
+ NADPH
-
- 10formylTHF
-
-
- H
- ⁺
-
-
- HO
- ₂
-
-
-
- H
+ ⁺
+
+ NADPH
+
+ 10formylTHF
+
+
+ H
+
-
-
-
- HO
- ₂
-
-
- NADP
- ⁺
-
- NADPH
-
- CO
- ₂
-
-
- H
- ⁺
-
- ⁺
+
+
+ HO
+ ₂
+
+
+
+
+
+
+
+ HO
+ ₂
+
+
+ NADP
+ ⁺
+
+ NADPH
+
+ Formate
- THF
- Pi
- ADP
-
-
-
- ATP
-
-
-
-
-
- 5,10mTHF
- 5,10meTHF
-
-
-
-
- NADH
-
- NAD
- ⁺
-
-
-
-
-
-
- NADPH
-
- NADP
- ⁺
-
-
-
-
-
- 2 H
-
- NH
- ₃
-
- 5forthf
-
-
-
- NADPH
-
- 2
- H
-
- NADP
-
- 5mTHF
-
-
-
-
-
- Amino acids synthesis / degradation
-
-
-
-
-
- Pentose Phosphate pathway
-
-
-
-
-
- Nucleotide synthesis
-
-
-
-
-
- Fatty acids / Cholesterol synthesis
-
-
-
-
-
- Urea cycle
-
-
-
-
-
- Ammonia detox
-
-
-
-
-
- Biomass
-
-
-
-
-
- Fatty acids β-oxidation
-
-
-
-
-
- Glutathione synthesis
-
-
-
-
-
- Glycolysis / Gluconeogenesis
-
-
-
- Ala
- AKG
- Glu
-
-
-
-
-
- GSSG
-
- GSH
-
-
- H
- ⁺
-
- NADH
-
- NAD
- ⁺
-
-
- HO
- ₂₂
-
- GSH
-
-
- 2 HO
- ₂
-
- GSH
-
-
-
-
- NADP
- ⁺
-
- GSH
-
-
- H
- ⁺
-
- NADPH
-
-
-
-
-
-
-
-
-
- GC
- Cys
-
- ATP
-
-
- Gly
- Pi
- ADP
-
-
- ATP
-
-
- Glu
- Pi
- ADP
-
-
-
-
- Mitochondrial space
-
-
-
- Glc
- Glc
- G6P
- F6P
- F1,6BP
- GA3P
- ATP
- ADP
-
- NAD
- ⁺
-
- NADH
-
-
-
-
-
-
-
- ATP
- ADP
-
-
-
-
-
- Pi
-
-
-
-
-
- HO
- ₂
-
- CO
+ ₂
+
+
+ H
+ ⁺
+
+ Formate
+ THF
+ Pi
-
- HO
- ₂
-
- Pi
-
-
-
-
-
-
-
- 1,3BPGA
- 3PG
- 2PG
- ADP
- ATP
-
-
-
-
-
- 2,3BPG
-
- HO
- ₂
-
- Pi
-
-
-
-
-
-
-
-
- PEP
-
-
- Pyr
-
- ADP
- ATP
-
-
- Lact
-
-
- H
- ⁺
-
- NADH
-
- NAD
- ⁺
-
+ id="tspan602">Pi
+ ADP
+
+
-
-
-
-
-
-
+
+ stroke-width="2.45082"
+ id="path611" />
+
+
+ ATP
+
+
+
-
-
- HO
- ₂
-
-
+
+
+
+
+ 5,10mTHF
+ 5,10meTHF
+
+
+
+
+ NADH
+
+ NAD
+ ⁺
+
+
+
+
+
+
+ NADPH
+
+ NADP
+ ⁺
+
+
+
+
+
+ 2 H
+
+ NH
+ ₃
+
+ 5forthf
+
+
+
+ NADPH
+
+ 2
+ H
+
+ NADP
+
+ 5mTHF
+
+
+
+
+
+ Amino acids synthesis / degradation
+
+
+
+
+
+ Pentose Phosphate pathway
+
+
+
+
+
+ Nucleotide synthesis
+
+
+
+
+
+ Fatty acids / Cholesterol synthesis
+
+
+
+
+
+ Urea cycle
+
+
+
+
+
+ Ammonia detox
+
+
+
+
+
+ Biomass
+
+
+
+
+
+ Fatty acids β-oxidation
+
+
+
+
+
+ Glutathione synthesis
+
+
+
+
+
+ Glycolysis / Gluconeogenesis
+
+
+
+ Ala
+ AKG
+ Glu
+
+
+
+
+
+ GSSG
+
+ GSH
+
+
+ H
+ ⁺
+
+ NADH
+
+ NAD
+ ⁺
+
+
+ HO
+ ₂₂
+
+ GSH
+
+
+ 2 HO
+ ₂
+
+ GSH
+
+
+
+
+ NADP
+ ⁺
+
+ GSH
+
+
+ H
+ ⁺
+
+ NADPH
+
+
+
+
+
+
+
+
-
-
- Putr
-
-
-
- ametam
- 5mta
-
- spermidine
-
-
-
- ametam
- 5mta
-
- spermine
-
-
- ⁺
- H
-
-
- ₂
- CO
-
-
-
- SAM
-
-
+
+ GC
+ Cys
+
+ ATP
+
+
+ Gly
+ Pi
+ ADP
+
+
+ ATP
+
+
+ Glu
+ Pi
+ ADP
+
+
+
+
+ Mitochondrial space
+
+
+
+ Glc
+ 5mdr1p
-
-
- 5mdru1p
-
-
-
-
- ₂
- HO
-
-
- dkmpp
- met
-
- Gln
-
- 2 H
- ⁺
-
- Glu
-
-
-
-
-
- HO
- ₂
-
- ATP
- Pi
- PPi
-
-
-
- Glc
+ G6P
+ F6P
+ F1,6BP
+ GA3P
+ ATP
+ ADP
+
+ NAD
+ ⁺
+
+ NADH
+
+
+
+
+
+
+
+ ATP
+ ADP
+
+
+
+
+
+ Pi
+
+
+
+
+
+ HO
+ ₂
+
+ Pi
+
+ HO
+ ₂
+
+ Pi
+
+
+
+
+
+
+
+ 1,3BPGA
+ 3PG
+ 2PG
+ ADP
+ ATP
+
+
+
+
+
+ 2,3BPG
+
+ HO
+ ₂
+
+ Pi
+
+
+
+
+
+
+
+
+ PEP
+
+
+ Pyr
+
+ ADP
+ ATP
+
+
+ Lact
+
+
+ H
+ ⁺
+
+ NADH
+
+ NAD
+ ⁺
+
+
+
+
+
+
+
+
+
+
+
+ HO
+ ₂
+
+
+
+
+ Putr
+
+
+
+ ametam
+ 5mta
+
+ spermidine
+
+
+
+ ametam
+ 5mta
+
+ spermine
+
+
+ ⁺
+ H
+
+
+ ₂
+ CO
+
+
+
+ SAM
-
- THF
- 5mTHF
-
-
-
- SAH
-
-
- HO
- ₂
-
- Adenosine
-
-
-
-
-
- Pi
- adenine
-
-
-
- PRPP
- PPi
- AMP
-
-
-
-
- ATP
-
- H
- ⁺
-
- ADP
- SAM
+
+ 5mdr1p
+
+
+ 5mdru1p
+
+
+
+
+ ₂
+ HO
+
+
+ dkmpp
+ met
+
+ Gln
+
+ 2 H
+ ⁺
+
+ Glu
+
+
+
+
+
+ HO
+ ₂
+
+ ATP
+ Pi
+ PPi
+
+
+
+ SAM
+
+ THF
+ 5mTHF
+
+
+
+ SAH
+
+
+ HO
+ ₂
+
+ Adenosine
+
+
+
+
+
+ Pi
+ adenine
+
+
+
+ PRPP
+ PPi
+ AMP
-
-
-
-
- Hcys
-
-
- 5mTHF
- THF
-
-
-
-
-
-
-
-
-
- ₂
- HO
-
-
- ₂
- O
-
- Pi
-
- ⁺
- 2 H
-
- formate
-
- AMP
+
+
+
+
+ ATP
+
+ H
+ ⁺
+
+ ADP
+ AMP
+
+
+
+
+ 2kmb
-
-
-
- Glu
- AKG
-
-
- Hcys
+
+
+ 5mTHF
+ THF
+
+
+
+
+
+
+
+
+
+ ₂
+ HO
+
+
+ ₂
+ O
+
+ Pi
+
+ ⁺
+ 2 H
+
+ formate
+
+ 2kmb
+
+
+
+ Glu
+ AKG
+
+ Putr
+
+
+
+
+
+
+
+ spermine
+
+
+
+
+ spermidine
+
+
+
+
+
+
+ ₂
+ CO
+
+
+
+ hcarn
+ ATP
+ AMP
+ PPi
+ His
+
+ 2 H
+ ⁺
+
+
+
+
+
+
+
+ ₂
+ HO
+
+ His
+
+
+
+ 4abutn
+
+
+ ₂
+ HO
+
+
+ NAD
+ ⁺
+
+
+
+
+ 4abut
+
+ ₂
+ CO
+
+
+ H
+ ⁺
+
+ NADH
+
+
+ Glu
+
+
+
+
+ ₂
+ HO
+
+
+ ₂
+ O
+
+
+ ₂₂
+ HO
+
+
+ ₃
+ NH
+
+
+
+
+
+
+ 2obut
+
+
+ 6Pgl
+
+ NADP
+ ⁺
+
+ NADPH
+
+ H
+ ⁺
+
+ 6PDG
+
+ NADP
+ ⁺
+
+ NADPH
+
+ CO
+ ₂
+
+
+ H
+ ⁺
+
+ Ru5P
+
+
+ HO
+ ₂
+
+
+
+
+
+
+
+ AMP
+ ATP
+
+
+ R5P
+
+
+
+
+ Xil5P
+
+
+
+
+ Sed7P
+ GA3P
+
+
+
+ F6P
+ Sed1,7BP
+ Ery4P
+ DHAP
+ ATP
+ ADP
+
+
+
+
+
+
+ Ery4P
+
+
+
+ GA3P
+ F6P
+ Xil5P
+
+
+
+ ADP
+ ATP
+ dTTP
+
+
+
+
-
-
- ₂
- CO
-
-
-
- hcarn
- ATP
- AMP
- PPi
- His
-
- 2 H
- ⁺
-
-
-
+
+
+
+ PRPP
+ Gly
+ 2 10fTHF
+ 2 THF
+ PPi
+ 4 ADP
+ Fum
+ 2 Gln
+ 2 Glu
+ 4 ATP
+ Asp
+
+ HO
+ ₂
+
+
+ CO
+ ₂
+
+ Asp
+ 2 ATP
+
+ QH
+ ₂
+
+ 2 ADP
+ Gln
+ Glu
+
+ HCO
+ ₃
+ ⁻
+
+ Q
+
+ H
+ ⁺
+
+ PPi
+
+ CO
+ ₂
+
+ UDP
+ ATP
+ ADP
+ dUDP
+
+ HO
+ ₂
+
+
+
+ dUMP
+ ADP
+ ATP
+ dTMP
+ 5,10meTHF
+ DHF
+ UTP
+ CTP
+ ADP
+ Pi
+ ATP
+
+ NH
+ ₃
+
+ CDP
+
+ HO
+ ₂
+
+ dCDP
+ ATP
+ ADP
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ UMP
+ GMP
+ GDP
+ dGDP
+
+ 2
+ HO
+
+ AMP
+ ADP
+ ADP
+ ATP
+
+ HO
+ ₂
+
+ dADP
+
+
+
+
+
+
+
+
+ ADP
+ ATP
+ dGTP
+ ADP
+ ATP
+
+
+
+
+
+
+ dATP
+ dCTP
+ dTDP
+ 4 Pi
+
+
+ IMP
+ 2 Pi
+
+
+
+
+
+
+
+ ADP
+ ATP
+
+
+
+
+
+
+ ADP
+ ATP
+
+
+
+
+
+
+ ADP
+ ATP
+
+
+
+
+
+
+
+
+
+
+
+ GTP
+ Asp
+ GDP
+ Pi
+ Fum
+
+ NAD
+ ⁺
+
+
+ HO
+ ₂
+
+ ATP
+
+ NH
+ ₃
+
+ NADH
+
+ H
+ ⁺
+
+ AMP
+ PPi
+
+
+ NADP
+ ⁺
+
+
+ NH
+ ₃
+
+
+ H
+ ⁺
+
+ NADPH
+
+
+
+
+
+ ADP
+ ATP
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ ADP
+ ATP
+ GTP
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ ATP
+
+ HCO
+ ⁻
+ ₃
+
+
+ H
+ ⁺
+
+ ADP
+ Pi
+
+
+
+ CoA
+ AcACP
+ ACP
+
+
+
+
+
+ CO
+ ₂
+
+
+ ACP
+
+
+
+ MalCoA
+
+ CoA
+ MalACP
+ ACP
+
+
+
+ AcCoA
+
+ HO
+ ₂
+
+ CoA
+ AcAcCoA
+
+
+
+
+ PalmCoA
+ CoA
+ AMP
+ PPi
+ ATP
+
+
+ Palm
+
+
+ AcAcACP
+ 14 NADPH
+
+ 14 NADP
+ ⁺
+
+
+ 6 HO
+ ₂
+
+
+ 6 CO
+ ₂
+
+ 6 MalACP
+ 7 ACP
+
+
+ 14 H
+ ⁺
+
+
+
+
+ HMGCoA
+ 3 ATP
+ CoA
+ 2 NADPH
+
+ 2 NADP
+ ⁺
+
+ 3 ADP
+
+ CO
+ ₂
+
+ Pi
+
+
+
+
+ 2 PPi
+ fPP
+ 2 ippPP
+ ippPP
+
+
+
+
+ 13 NADPH
+
+ 2
+ 10 O
+
+
+ 13 NADP
+ ⁺
+
+ 2 PPi
+ formate
+
+ 2 CO
+ ₂
+
+ Chol
+ fPP
+
+ 15 HO
+ ₂
+
+
+
+
+ 16 H
+ ⁺
+
+
+ AcCoA
+
+ HMGCoA
+
-
-
-
-
- ₂
- HO
-
- His
-
-
-
- 4abutn
-
-
- ₂
- HO
-
-
- NAD
- ⁺
-
-
-
-
- 4abut
-
- ₂
- CO
-
-
- H
- ⁺
-
- NADH
-
+
-
- Glu
-
-
-
-
- ₂
- HO
-
-
- ₂
- O
-
-
- ₂₂
- HO
-
-
- ₃
- NH
-
-
-
-
- Putr
-
-
-
-
-
-
-
- spermine
-
-
-
-
- spermidine
-
-
-
-
-
-
+
+ AcCoA
+ CoA
+
+
+
+
+
+
+
+ 2obut
-
-
-
- 6Pgl
-
- NADP
- ⁺
-
- NADPH
-
- H
- ⁺
-
- 6PDG
-
- NADP
- ⁺
-
- NADPH
-
- CO
- ₂
-
-
- H
- ⁺
-
- Ru5P
- 3
+ NH
+
+
-
- HO
- ₂
-
-
-
-
-
-
-
- AMP
- ATP
-
-
- R5P
-
-
-
-
- Xil5P
-
-
-
-
- Sed7P
- GA3P
-
-
-
- F6P
- Sed1,7BP
- Ery4P
- DHAP
- ATP
- ADP
-
-
-
-
-
-
- Ery4P
-
-
+
-
- GA3P
- F6P
- Xil5P
-
-
- ADP
- ATP
- dTTP
-
- Ci
+
+
+ 3
+ NH
+
+
+ H
+ ⁺
+
+
+ ⁻
+ ₃
+ HCO
+
+ 2 ADP
+ Pi
+
+
+ 2 ATP
+
+ Orn
+
+ H
+ ⁺
+
+
+ Orn
+
+ H
+ ⁺
+
+
+ Ci
+
+ CP
+ Pi
+ Orn
+
+
+
+
+
+
+
+
+ Pi
+
+ H
+ ⁺
+
+ Pi
+
+
+ ATP
+ ADP
+ ATP
+ ADP
+
+
+ GTP
+ GDP
+ GTP
+ GDP
+
+
+
+
+ HO
+ ₂
+
+
+ HO
+ ₂
+
+
+
+ O
+ ₂
+
+
+ O
+ ₂
+
+
-
-
-
-
-
- PRPP
- Gly
- 2 10fTHF
- 2 THF
- PPi
- 4 ADP
- Fum
- 2 Gln
- 2 Glu
- 4 ATP
- Asp
-
- HO
- ₂
-
-
- CO
- ₂
-
- Asp
- 2 ATP
-
- QH
- ₂
-
- 2 ADP
- Gln
- Glu
-
- HCO
- ₃
- ⁻
-
- Q
-
- H
- ⁺
-
- PPi
-
- CO
- ₂
-
- UDP
- ATP
- ADP
- dUDP
-
- HO
- ₂
-
-
-
+
+
+ NADH
+
+ NAD
+ ⁺
+
+
+ 0.95 QH
+ ₂
+
+
+ 4.75 H
+ ⁺
+
+ 0.95 Q
+
+ 3.8 H
+ ⁺
+
+
+ FADH
+ ₂
+
+ FAD
+
+ QH
+ ₂
+
+ Q
+
+ 2 Cytc-ox
+ 2 Cytc-red
+ Q
+
+ 2 H
+ ⁺
+
+
+ QH
+ ₂
+
+
+
+ 4 H
+ ⁺
+
+ 4 Cytc-red
+ 4 Cytc-ox
+
+ 2 HO
+ ₂
+
+
+ 8 H
+ ⁺
+
+
+ O
+ ₂
+
+
+
+ GSH
+ GSH
+
+
+
+ Pi
+ Pi
+
+
+
Gly
+ Gly
+
+ Mal
+ AKG
+ AKG
+
+
+
+ ADP
+ Pi
+ ATP
+
+ HO
+ ₂
+
+
+ 4 H
+ ⁺
+
+ 10-formylTHF
+ 5,10mTHF
+
+ HO
+ ₂
+
+ 5,10meTHF
+
+
+
+ NADPH
+
+ NADP
+ ⁺
+
+
+ H
+ ⁺
+
+ THF
+
+ HO
+ ₂
+
+
+ CO
+ ₂
+
+
+ CO
+ ₂
+
+
+
+
+
+ dUMP
- ADP
- ATP
- dTMP
- 5,10meTHF
- DHF
- UTP
- CTP
- ADP
- Pi
- ATP
-
- NH
- ₃
-
- CDP
-
- HO
- ₂
-
- dCDP
- ATP
- ADP
-
-
-
-
-
-
-
-
- UMP
- GMP
- GDP
- dGDP
-
- 2
- HO
-
- AMP
- ADP
- ADP
- ATP
-
- HO
- ₂
-
- dADP
-
-
-
-
-
-
-
-
- ADP
- ATP
- dGTP
- ADP
- ATP
-
+ id="tspan3068">NADH
+ NADPH
+
+ NADP
+ ⁺
+
+
+ NAD
+ ⁺
+
+
+
+ H
+ ⁺
+
+
+
+ H
+ ⁺
+
+
+
+
+ HO
+ ₂₂
+
+
+ 2 HO
+ ₂
+
+ 2 GSH
+
+ O
+ ₂
+ ⁻
+
+
+ O
+ ₂
+ ⁻
+
+
+ 2 H
+ ⁺
+
+
+ O
+ ₂
+
+
+
+ GSSG
+
+
-
-
-
-
- dATP
- dCTP
- dTDP
- 4 Pi
-
-
- IMP
- 2 Pi
-
-
-
-
-
-
-
- ADP
- ATP
-
-
-
-
-
-
- ADP
- ATP
-
+ stroke-width="2.22804" />
-
-
-
- ADP
- ATP
-
-
-
-
-
-
-
-
-
- GTP
- Asp
- GDP
- Pi
- Fum
-
- NAD
- ⁺
-
-
- HO
- ₂
-
- ATP
-
- NH
- ₃
-
- NADH
-
- H
- ⁺
-
- AMP
- PPi
-
-
- NADP
- ⁺
-
-
- NH
- ₃
-
-
- H
- ⁺
-
- NADPH
-
-
-
-
-
- ADP
- ATP
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- ADP
- ATP
- GTP
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- ATP
-
- HCO
- ⁻
- ₃
-
-
- H
- ⁺
-
- ADP
- Pi
-
-
-
-
+ CoA
- AcACP
- ACP
-
-
-
-
+ x="1674.49"
+ y="1273.16"
+ id="tspan3192">NADH
+ id="text7967-0-3-2-6-6-4-4-3-8-7-4_2">
CO
- ₂
-
-
- ACP
-
-
-
- MalCoA
-
- CoA
- MalACP
- ACP
-
-
-
- AcCoA
-
- HO
+ id="text3197">H
₂
+ id="text3201">⁺
- CoA
- AcAcCoA
-
-
-
-
- PalmCoA
- CoA
- AMP
- PPi
- ATP
-
-
- Palm
-
-
- AcAcACP
- 14 NADPH
+ id="text7967-0-3-2-6-6-4-4-3-8-6-4">
14 NADP
- ⁺
-
-
- 6 HO
- ₂
-
-
- 6 CO
- ₂
-
- 6 MalACP
- 7 ACP
-
-
+ id="text3206">NAD
14 H
- ⁺
+ id="text3210">⁺
-
-
-
- HMGCoA
- 3 ATP
- CoA
- 2 NADPH
+ x="1674.49"
+ y="1235.16"
+ id="tspan3213">NADPH
- 2 NADP
- ⁺
-
- 3 ADP
-
- CO
+ id="text7967-0-3-2-6-6-4-4-3-8-7-6-4_2">
₂
-
- Pi
-
-
-
-
- 2 PPi
- fPP
- 2 ippPP
- ippPP
-
-
-
-
- 13 NADPH
-
- 2
- 10 O
-
-
+ id="text3218">H
13 NADP
- ⁺
+ id="text3222">⁺
- 2 PPi
- formate
- 2 CO
+ id="text7967-0-3-2-6-6-4-4-3-8-6-9-4">
₂
-
- Chol
- fPP
-
- 15 HO
- ₂
-
-
-
-
- 16 H
+ id="text3227">NADP
⁺
+ id="text3231">⁺
-
- AcCoA
-
- HMGCoA
-
-
-
-
- AcCoA
- CoA
-
-
-
-
-
-
- 3
- NH
-
-
-
-
-
- Ci
-
-
- 3
- NH
-
-
- H
- ⁺
-
-
- ⁻
- ₃
- HCO
-
- 2 ADP
- Pi
-
-
- 2 ATP
-
- Orn
-
- H
- ⁺
-
-
- Orn
-
- H
- ⁺
-
-
- Ci
-
- CP
- Pi
- Orn
-
-
-
-
-
-
-
-
- Pi
-
+
+
+
+
+
H
+ id="text3241">CO
⁺
-
- Pi
-
-
- ATP
- ADP
- ATP
- ADP
-
-
- GTP
- GDP
- GTP
- GDP
-
-
-
-
+ id="text3245">₂
+
+
HO
+ id="text3250">HCO
₂
-
-
- HO
+ id="text3254">₃
₂
-
-
+ id="text3258">⁻
+
+
+
+ H
+ ⁺
+
+
+ HO
+ ₂
+
+
+
+ ADP
+
+
+
+ Ser
+ Ser
+
+
+
+ 0.05 O
+ ₂
+
+
+
+ 0.05 O
+ ₂
+ ⁻
+
+
+
+ DHAP
+ DHAP
+ FAD
+
+
+ FADH
+ ₂
+
+
+ Gly3P
+ Gly3P
+
+
+
+
+ AcCoA
+ Pyr
+
+
+ NAD
+ ⁺
+
+
+ NADP
+ ⁺
+
+ NADH
+
+ CO
+ ₂
+
+
+ H
+ ⁺
+
+
+
+
+
+ Pi
+ ADP
+
+ H
+ ⁺
+
+ ATP
+
+ HCO
+ ₃
+ ⁻
+
+
+ NAD
+ ⁺
+
+ CoA
+
+ 2
+ CO
+
+
+ H
+ ⁺
+
+ NADH
+
+
+
+
+
+
+
+
+ NADPH
+
+ H
+ ⁺
+
+
+ CO
+ ₂
+
+
+
+
+
+ Pi
+
+
+
+
+
+ ATP
+
+
+
+ Formate
+
+
+ Formate
+
+ Formate
+
+
+
+
+
+
+
+
+
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+ Mal
+
+ H
+ ⁺
+
+
+ OAA
+ Cit
+ Isocit
+ AKG
+
+ NADP
+ ⁺
+
+ SuCoA
+ Succ
+ Fum
+ Mal
+
+ FAD
+
+ FADH
+ ₂
+
+
+ NAD
+ ⁺
+
+
+
+ HO
+ ₂
+
+ CoA
+
+
+
+
+ HO
+ ₂
+
+
+
+
+
+
+
+ NADH
+
+ H
+ ⁺
+
+
+
+
+ GDP
+ Pi
+ CoA
+ GTP
+
+
+
+
+ CoA
+ id="text6973-9-0-3_2">
O
+ id="text3701">NAD
₂
+ id="text3705">⁺
+
+
+ NADH
+ id="CO2_4">
O
+ id="text3715">CO
₂
+
+
+ H
+ ₂
+ id="text3728">⁺
+
+
+ NADPH
+ ⁺
+
+
+ CO
+ ₂
+
+
+ H
+ ⁺
+
+
+
+
+
+ NAD
+ ⁺
+
+
+ NADH
+ ⁺
+
+
+ H
+ ⁺
+
+
+ CO
+ ₂
+
+
+
+
+
+
+
+
+
+ stroke-width="2.23952"
+ stroke-miterlimit="5.75877"
+ id="path3805" />
+
-
- NADH
-
- NAD
- ⁺
-
-
- 0.95 QH
- ₂
-
-
- 4.75 H
- ⁺
-
- 0.95 Q
-
- 3.8 H
- ⁺
-
-
- FADH
- ₂
-
- FAD
-
- QH
- ₂
-
- Q
-
- 2 Cytc-ox
- 2 Cytc-red
- Q
-
- 2 H
- ⁺
-
-
- QH
- ₂
-
-
-
- 4 H
- ⁺
-
- 4 Cytc-red
- 4 Cytc-ox
-
- 2 HO
- ₂
-
-
- 8 H
- ⁺
-
-
- O
- ₂
-
-
-
- GSH
- GSH
-
-
+
+
+
+
+ NADH
+
+ H
+ ⁺
+
+
+ NH
+ ₃
+
+
+ NAD
+ ⁺
+
+
+ HO
+ ₂
+
+ NADPH
+
+ H
+ ⁺
+
+
+ NH
+ ₃
+
+
+ NADP
+ ⁺
+
+
+ HO
+ ₂
+
+
+
+
+
+
+
+
+
+ NADP
+ ⁺
+
+ NADPH
+
+ H
+ ⁺
+
+ DHF
+
+
+
+
+ NADP
+ ⁺
+
+ NADPH
+
+ H
+ ⁺
+
+ Folate
+
+
+
+
+ 4 H
+ ⁺
+
+
+ 4 H
+ ⁺
+
+
+ NADH
+
+ H
+ ⁺
+
+
+ HO
+ ₂
+
+
+ NAD
+ ⁺
+
+
+
+
+ Gln
+ Glu
+
+
+ Gln
+
+
+
+ NH
+ ₃
+
+ Glu
+
+ HO
+ ₂
+
+
+
+
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+
+ Folate
+
+
+
+
+ +
+ H
+
+ Mal
+
+ Fum
+
+
+
+ Pi
+ Pi
+ Fum
+
+
+ GluSA
+
+
+
+ GluSA
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ Val, 3mob, propCoA
+
+
+ Leu
+ Leu
+
+
+
+
+ Val
+ Val
+
+
+
- Pi
- Pi
-
-
-
- Gly
- Gly
-
- Mal
- AKG
- AKG
-
-
+
+
+
-
- ADP
- Pi
- ATP
-
- HO
- ₂
-
-
- 4 H
- ⁺
-
-
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+ 10-formylTHF
- 5,10mTHF
-
- HO
- ₂
-
- 5,10meTHF
-
-
-
- NADPH
-
- NADP
- ⁺
-
-
- H
- ⁺
-
- THF
-
- HO
- ₂
-
-
- CO
- ₂
-
-
- CO
- ₂
-
-
-
-
-
- NADH
- NADPH
-
- NADP
- ⁺
-
-
- NAD
- ⁺
-
-
-
- H
- ⁺
-
-
-
- H
- ⁺
-
-
-
-
- HO
- ₂₂
-
-
- 2 HO
- ₂
-
- 2 GSH
-
- O
- ₂
- ⁻
-
-
- O
- ₂
- ⁻
-
-
- 2 H
- ⁺
-
-
- O
- ₂
-
-
-
- GSSG
-
-
-
-
- NADH
-
- H
- ⁺
-
-
- NAD
- ⁺
-
- NADPH
-
- H
- ⁺
-
-
- NADP
- ⁺
-
-
-
-
-
-
-
-
- CO
- ₂
-
-
- HCO
- ₃
- ⁻
-
-
-
- H
- ⁺
-
-
- HO
- ₂
-
-
-
- ADP
-
-
-
- Ser
- Ser
-
-
-
- 0.05 O
- ₂
-
-
-
- 0.05 O
- ₂
- ⁻
-
-
-
- DHAP
- DHAP
- FAD
-
-
- FADH
- ₂
-
-
- Gly3P
- Gly3P
-
-
-
-
- AcCoA
- Pyr
-
-
- NAD
- ⁺
-
-
- NADP
- ⁺
-
- NADH
-
- CO
- ₂
-
-
- H
- ⁺
-
-
-
-
-
- Pi
- ADP
-
- H
- ⁺
-
- ATP
-
- HCO
- ₃
- ⁻
-
-
- NAD
- ⁺
-
- CoA
-
- 2
- CO
-
-
- H
- ⁺
-
- NADH
-
-
-
-
-
-
-
-
- NADPH
-
- H
- ⁺
-
-
- CO
- ₂
-
-
-
-
-
- Pi
-
-
-
-
-
- ATP
-
-
-
- Formate
-
-
- Formate
-
- Formate
-
-
-
-
-
-
-
-
-
- H
- ⁺
-
-
- H
- ⁺
-
-
- H
- ⁺
-
- Mal
-
- H
- ⁺
-
-
- OAA
- Cit
- Isocit
- AKG
-
- NADP
- ⁺
-
- SuCoA
- Succ
- Fum
- Mal
-
- FAD
-
- FADH
- ₂
-
-
- NAD
- ⁺
-
-
-
- HO
- ₂
-
- CoA
-
-
-
-
- HO
- ₂
-
-
-
-
-
-
-
- NADH
-
- H
- ⁺
-
-
-
-
- GDP
- Pi
- CoA
- GTP
-
-
-
-
- CoA
-
- NAD
- ⁺
-
-
-
- NADH
-
- CO
- ₂
-
-
- H
- ⁺
-
-
-
- NADPH
- ⁺
-
-
- CO
- ₂
-
-
- H
- ⁺
-
-
-
-
-
- NAD
- ⁺
-
-
- NADH
- ⁺
-
-
- H
- ⁺
-
-
- CO
- ₂
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- NADH
-
- H
- ⁺
-
-
- NH
- ₃
-
-
- NAD
- ⁺
-
-
- HO
- ₂
-
- NADPH
-
- H
- ⁺
-
-
- NH
- ₃
-
-
- NADP
- ⁺
-
-
- HO
- ₂
-
-
-
-
-
-
-
-
-
- NADP
- ⁺
-
- NADPH
-
- H
- ⁺
-
- Lys
+ DHF
-
-
-
-
- NADP
- ⁺
-
- NADPH
-
- H
- ⁺
-
- Lys
+
+
+ 3mob
+ 3mob
+
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+
+
+
+
+ 4mop
+ 4mop
+
+ H
+ ⁺
+
+
+ H
+ ⁺
+
+
+
+
+
+ Folate
-
-
-
-
- 4 H
- ⁺
-
-
- 4 H
- ⁺
-
-
- NADH
-
- H
- ⁺
-
-
- HO
- ₂
-
-
- NAD
- ⁺
-
+ id="tspan4250">2oxoadp
+ 2oxoadp
+
+ AKG
+ AKG
+
+
+ propCoA
+ propCoA
+
+
+
+
+
+ 5,10meTHF
+ 5,10meTHF
+
+
+
+
+
+ AKG
+ Glu
+
+ stroke-width="2.23952"
+ id="path4290" />
-
-
+
+
+
+ Asp
+ Glu
+
+ Gln
- Glu
-
-
- H
+ Gln
-
-
-
- NH
- ₃
-
- ⁺
+
+
+ H
+ Glu
-
- HO
- ₂
-
+ letter-spacing="0em"
+ id="text4318">⁺
+
+ Glu
+
+
+
+
+ AcAcCoA
+
+
+ CoA
+ 2 AcCoA
+
+
+
+ NADH
+
+ NAD
+ ⁺
+
+
+ H
+ ⁺
+
+
-
+ stroke-width="1.1381" />
- H
- ⁺
+ id="path77229-7">
+
+
- H
- ⁺
+ id="path77231-8">
+
+
+
+
+
- H
- ⁺
+ id="path77229-7-3">
+
+
- H
- ⁺
-
-
- Folate
-
-
-
- +
- H
-
- Mal
-
- Fum
-
-
-
- Pi
- Pi
- Fum
-
-
- GluSA
-
-
-
- GluSA
-
-
-
-
-
-
+ id="path77231-8-4">
+
-
-
-
-
-
-
-
-
+ stroke-width="1.1381"
+ id="path4382" />
- Val, 3mob, propCoA
-
-
- Leu
- Leu
-
-
-
-
-
- Val
- Val
-
-
-
-
-
-
-
-
- H
- ⁺
-
-
- H
- ⁺
-
- Lys
- Lys
-
-
- 3mob
- 3mob
-
- H
- ⁺
-
-
- H
- ⁺
-
-
-
-
-
- 4mop
- 4mop
-
- H
- ⁺
-
-
- H
- ⁺
-
-
-
-
-
- 2oxoadp
-
+ HMGCoA
+ Leu, 4mop
+ Lys, 2oxoadp
+
+ AcCoA
+
+ HO
+ ₂
+
+ CoA
+
+ H
+ ⁺
+
+
+
+ HO
+ ₂
+
+
+
+
+
+
+
+
+
+
+
+
+
+ Ci
+ Orn
+ ArgSuc
+ Arg
+ Fum
+
+
+ HO
+ ₂
+
+
+ 2oxoadp
-
- AKG
- AKG
-
-
- propCoA
- propCoA
-
-
-
-
-
- 5,10meTHF
- 5,10meTHF
-
-
-
-
-
- AKG
- Glu
-
-
-
-
-
+ id="tspan4471">Urea
- Asp
- Glu
-
- H
- ⁺
-
-
- H
- ⁺
-
- Glu
-
-
-
-
- AcAcCoA
-
-
- CoA
- 2 AcCoA
-
-
-
- NADH
-
- NAD
- ⁺
-
-
- H
- ⁺
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- HMGCoA
- Leu, 4mop
- Lys, 2oxoadp
+ stroke-width="2.49358" />
- AcCoA
-
- HO
- ₂
-
- CoA
-
- H
- ⁺
-
-
-
- HO
- ₂
-
-
-
-
-
-
-
-
-
-
-
-
-
- Ci
- Orn
- ArgSuc
- Arg
- Fum
-
-
- HO
- ₂
-
-
- Urea
-
-
-
-
-
-
-
-
- 3
- NH
-
-
-
-
- PalmCarn
- PalmCarn
-
-
-
- Carn
- Carn
- PalmCoA
-
-
-
- Carn
- CoA
- 8 AcCoA
- 7 FAD
-
- 7 NAD
- ⁺
-
- 7 CoA
-
- 7 HO
- ₂
-
-
-
- 7 FADH
- ₂
-
- 7 NADH
-
- 7 H
- ⁺
-
-
-
-
-
- H
- ⁺
-
-
+ stroke-width="2.32327" />
+
+
+
+
+
+
CO
- ₂
-
-
- HCO
- ₃
+ id="text4482">3
⁻
-
-
-
- HO
- ₂
-
-
- NH
+
+
+
+
+ PalmCarn
+ PalmCarn
+
+
+
+ Carn
+ Carn
+ PalmCoA
+
+
+
+ Carn
+ CoA
+ 8 AcCoA
+ 7 FAD
+
+ 7 NAD
+ ⁺
+
+ 7 CoA
+
+ 7 HO
+ ₂
+
+
+
+ 7 FADH
+ ₂
+
+ 7 NADH
+
+ 7 H
+ ⁺
+
+
+
+
+
+ H
+ ⁺
+
+
+ ADP
- Pi
-
- HO
- ₂
-
- CO
+ ATP
-
-
-
- H
- ⁺
-
- PPi
- Pi
- Pi
-
- HO
- ₂
-
-
-
-
-
- 0.01 dTTP
- 0.01 dATP
- 0.01 dGTP
- ₂
+
+
+ HCO
+ ₃
+ ⁻
+
+
+
+ HO
+ ₂
+
+
+ ADP
+ Pi
+
+ HO
+ ₂
+
+ ATP
+
+
+
+ H
+ ⁺
+
+ PPi
+ Pi
+ Pi
+
+ HO
+ ₂
+
+
+
+
+
+ 0.01 dTTP
+ 0.01 dATP
+ 0.01 dGTP
+ 0.05 UTP
+ 0.01 dCTP
+ 0.04CTP
+ 0.27 Palm
+ 0.20 Chol
+
+ 0.05 UTP
- 0.01 dCTP
- 0.04CTP
- 0.27 Palm
- 0.20 Chol
-
- 0.28 G6P
-
-
- 20.65 H20
- 20.70 ATP
-
- 0.04 GTP
- 0.36 Arg
- 0.05 Cys
- 0.28 G6P
+
+
+ 0.39 Glu
- 0.35 Asp
- 0.33 Gln
- 0.28 Asn
- 0.29 Ile
- 0.12 His
- 0.54 Gly
- 0.59Lys
- 0.41 Pro
- 0.26 Phe
- 0.15 Met
- 0.55 Leu
- 20.65 H20
+ 0.01 Trp
- 0.31Thr
- 0.16 Tyr
- 0.35Val
- 0.39 Ser
- 0.51 Ala
- Biomass
- 20.65 Pi
- 20.65ADP
- 20.65 H
+ font-size="16px"
+ letter-spacing="0em">20.70 ATP
+
+ 0.04 GTP
+ 0.36 Arg
+ 0.05 Cys
+ 0.39 Glu
+ 0.35 Asp
+ 0.33 Gln
+ 0.28 Asn
+ 0.29 Ile
+ 0.12 His
+ 0.54 Gly
+ 0.59Lys
+ 0.41 Pro
+ 0.26 Phe
+ 0.15 Met
+ 0.55 Leu
+ 0.01 Trp
+ 0.31Thr
+ 0.16 Tyr
+ 0.35Val
+ 0.39 Ser
+ 0.51 Ala
+ Biomass
+ 20.65 Pi
+ 20.65ADP
+ 20.65 H
+
+
+
-
+
+
+
+
+
+ H
+ ⁺
+
+
+ NADH
+
+ Gly3P
+
+
+
+ GTP
+
+ CO
+ ₂
+
+ GDP
+
+
+
+
+
+
+
+
+
+
+
+
+
+ AKG
+ Iso
+ NADPH
+
+ H
+ ⁺
+
+
+ NADP
+ ⁺
+
+
+
+
-
-
-
- H
- ⁺
-
-
- NADH
-
- NAD
- ⁺
-
-
- Gly3P
-
-
-
- GTP
-
- CO
- ₂
-
- GDP
-
-
-
-
-
-
-
-
-
-
-
-
-
- AKG
- Iso
- NADPH
-
- H
- ⁺
-
-
- NADP
- ⁺
-
-
-
-
-
- CO
- ₂
-
-
-
- ATP
- CoA
- Pi
- PPi
- AMP
- ADP
-
- Cit
-
-
-
+ CO
+ ₂
+
+
+
+ ATP
+ CoA
+ Pi
+ ADP
+
+ Cit
+
+
+ Mal
+ Glu
+
+
+
+ Asp
+ Fum
+
+
+
+ NH
+ ₃
+
+
+
+
+ NADPH
+
+ H
+ ⁺
+
+
+ CO
+ ₂
+
+
+ NADP
+ ⁺
+
+
+
+ OAA
+
+ H
+ ⁺
+
+ NADH
+
+ NAD
+ ⁺
+
+
+
+
+
+
+
+
+
+ HO
+ ₂
+
+
+
+ 3PPyr
+ NADH
+
+ H
+ ⁺
+
+
+ NAD
+ Mal
- Glu
-
-
-
- Asp
- Fum
-
-
-
- NH
- ₃
-
-
-
+ font-size="12px"
+ letter-spacing="0em"
+ id="text5015">⁺
+
+
+
+
+
+
+ CySS
+
+ 2 GSH
+ GSSG
+ 2 Cys
+
+
+
+
+ H
+ ⁺
+
+ NADPH
+ NADP
+ NADH
+
+ H
+ ⁺
+
+ NAD
+
+
+
+ HO
+ ₂
+
+
+ NH
+ ₃
+
+
+
+ Pyr
+
+
+
+
+
+ Asn
+ AMP
+ Glu
+ PPi
+ ATP
+ Gln
+
+ HO
+ ₂
+
+
+
+ HO
+ ₂
+
+
+ NH
+ ₃
+
+
+
+
+ Asp
+
+
+ P5C
+ Pro
+
+
+
+
+
+ H
+ ⁺
+
+ NADH
+
+ H
+ ⁺
+
+ NADPH
+
+ NAD
+ ⁺
+
+
+ NADP
+ ⁺
+
+
+ GluSA
+
+ HO
+ ₂
+
+
+
+
+
+
+
+
+
+ NH
+ ₃
+
+ Gln
+
+ HO
+ ₂
+
+
+ NH
+ ₃
+
+ ATP
+
+
+ ADP
+ Pi
+
+
+
+ O
+ ₂
+
+ Trp
+
+
+ Lfmkynr
+
+
+ formate
+
+ H
+ ⁺
+
+
+
+
+ HO
+ ₂
+
+
+ Glu
+ urcan
+
+
+
+ NH
+ ₃
+
+
+ His
+
+
+
+
+ HO
+ ₂
+
+
+
+ 4izp
+ forglu
+
+ H
+ ⁺
+
+ 5forthf
+
+
+ H
+
+ HO
+ ₂
+
+
+
+
+
+ THF
+ hgentis
+
+ hpp
+
+
+ O
+ ₂
+
+
+ CO
+ ₂
+
+
+
+
+ 4mlacac
+
+
+ O
+ ₂
+
+
+ H
+ ⁺
+
+
+
+
+
+ 4fumacac
+
+
+
+
+
+ HO
+ ₂
+
+
+ H
+ ⁺
+
+ Fum
+ AcAc
+
+
+
+
+ CoA
+ ATP
+ PPi
+ AMP
+ AcAcCoA
+
+
+
+ Lkynr
+
+
+ anth
+
+ H
+ ⁺
+
+
+ HO
+ ₂
+
+
+
+
+
+
- NADPH
-
- H
- ⁺
-
-
- CO
- ₂
-
-
- NADP
- ⁺
-
-
-
- OAA
-
- H
- ⁺
-
- NADH
-
- NAD
- ⁺
-
+ d="m 927.414,685.415 15.934,15.933 z"
+ fill="#aaccee"
+ id="path5528" />
-
-
-
-
-
-
-
- HO
- ₂
-
-
-
- 3PPyr
- NADH
-
- H
- ⁺
-
-
- NAD
- ⁺
-
-
-
-
-
-
- CySS
-
- 2 GSH
- GSSG
- 2 Cys
-
-
-
-
- H
- ⁺
-
- NADPH
- NADP
- NADH
-
- H
- ⁺
-
- NAD
-
-
-
- HO
- ₂
-
-
- NH
- ₃
-
-
-
- Pyr
-
-
-
-
-
- Asn
- AMP
- Glu
- PPi
- ATP
- Gln
-
- HO
- ₂
-
-
-
- HO
- ₂
-
-
- NH
- ₃
-
-
-
-
- Asp
-
-
- P5C
- Pro
-
-
-
-
-
- H
- ⁺
-
- NADH
-
- H
- ⁺
-
- NADPH
-
- NAD
- ⁺
-
-
- NADP
- ⁺
-
-
- GluSA
-
- HO
- ₂
-
+ stroke-width="1.1381"
+ id="path5530" />
+
+
+
-
-
-
-
-
-
-
- NH
- ₃
-
- Gln
-
- HO
- ₂
-
-
- NH
- ₃
-
- ATP
-
-
- ADP
- Pi
-
-
-
- O
- ₂
-
- Trp
-
-
- Lfmkynr
-
-
- formate
-
- H
- ⁺
-
-
-
-
- HO
- ₂
-
-
- Glu
-
+
+
+ 2oxoadp
+
+
+
+ Thr
+
+
+ NH
+ ₃
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+
+ 2obut
+ propCoA
+
+
+ CoA
+ NAD
+ NADH
+
+ CO
+ ₂
+
+
+
+
+ Tyr
+
+
+
+ AKG
+ Glu
+
+
+ urcan
-
-
-
- NH
- ₃
-
-
- His
-
-
-
-
- HO
- ₂
-
-
-
- 3mob
+
+ 4izp
- forglu
-
- H
- ⁺
-
- 5forthf
-
-
- H
-
- HO
- ₂
-
-
-
-
- Val
+
THF
-
- Lkynr
-
-
- anth
-
- H
- ⁺
-
-
- HO
- ₂
-
-
-
-
+ id="text6742"
+ transform="translate(1099,632)"
+ fill="#000000"
+ xml:space="preserve"
+ style="white-space:pre"
+ font-family="Arial"
+ font-size="12px"
+ letter-spacing="0em">Glu
+ AKG
+
+
+
+
+
+
+
+
+
-
-
-
-
-
-
-
-
-
- 2oxoadp
-
-
-
- Thr
-
-
- NH
- ₃
-
-
-
-
-
-
+
+
+
+
+ 4mop
+
+ Leu
+
+ Glu
+ AKG
+
+
+
+ id="path77229-0-5-3-7-0">
+ id="path5658" />
-
-
+ id="path5660" />
+
+
+ id="path5663" />
-
-
- 2obut
- propCoA
-
-
- CoA
- NAD
- NADH
-
- CO
- ₂
-
-
-
-
- hgentis
-
- hpp
-
-
- O
- ₂
-
-
- CO
- ₂
-
-
-
-
- 4mlacac
-
-
- O
- ₂
-
-
- H
- ⁺
-
-
-
-
-
- 4fumacac
-
-
-
-
-
- HO
- ₂
-
-
- H
- ⁺
-
- Fum
- AcAc
-
-
-
-
- CoA
- ATP
- PPi
- AMP
- AcAcCoA
-
-
-
- Tyr
-
-
-
- AKG
- Glu
-
-
- Phe
-
-
-
-
-
-
- BH4
- BH2
-
- HO
- ₂
-
-
- O
- ₂
-
-
-
-
- 3mob
-
- Val
-
- Glu
- AKG
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- 4mop
-
- Leu
-
- Glu
- AKG
-
-
-
-
-
-
-
-
-
-
-
-
-
-
- Cyst
- Cys
-
-
- NH
- ₃
-
-
+
+
+
+
+ Cyst
+ Cys
+
+
+ NH
+ 2-obut
-
- HO
- ₂
-
-
-
-
-
-
-
- HO
- ₂
-
- Hcys
-
-
- Gly
- ₃
+
+ 2-obut
+
+ HO
+ ₂
+
+
+
+
+
+
+
+ HO
+ ₂
+
+ Hcys
+
+
+ Gly
+ THF
+
+ THF
-
- HO
- ₂
-
- HO
+ 5,10meTHF
-
-
-
-
-
- HO
- ₂
-
- ₂
+
+ 5,10meTHF
+
+
+
+
+
+ HO
+ Pi
-
-
-
-
- Ser
-
- NH
- ₃
-
-
-
-
-
-
-
-
- 3PSer
- ₂
+
+ Pi
+
+
+
+
+ Ser
+
+ NH
+ Glu
- AKG
-
-
-
-
+ letter-spacing="0em"
+ id="text5768">₃
+
+
+
+
+
+
+
+
+ 3PSer
+ Glu
+ AKG
+
+
+