Mercurial > repos > bimib > cobraxy
changeset 490:c6ea189ea7e9 draft
Uploaded
author | francesco_lapi |
---|---|
date | Mon, 29 Sep 2025 15:13:21 +0000 |
parents | 97eea560a10f |
children | 7a413a5ec566 |
files | COBRAxy/local/models/ENGRO2.xml COBRAxy/metabolic_model_setting.py COBRAxy/metabolic_model_setting.xml COBRAxy/ras_generator.py COBRAxy/utils/model_utils.py |
diffstat | 5 files changed, 2025 insertions(+), 1880 deletions(-) [+] |
line wrap: on
line diff
--- a/COBRAxy/local/models/ENGRO2.xml Mon Sep 29 10:33:26 2025 +0000 +++ b/COBRAxy/local/models/ENGRO2.xml Mon Sep 29 15:13:21 2025 +0000 @@ -10771,7 +10771,6 @@ <fbc:geneProductRef fbc:geneProduct="G_ACE2"/> </fbc:and> <fbc:geneProductRef fbc:geneProduct="G_SLC6A9"/> - <fbc:geneProductRef fbc:geneProduct="G_SLC6A9"/> <fbc:geneProductRef fbc:geneProduct="G_SLC7A5"/> <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> <fbc:geneProductRef fbc:geneProduct="G_SLC6A5"/> @@ -11777,7 +11776,6 @@ <fbc:geneProductRef fbc:geneProduct="G_SLC7A6"/> <fbc:geneProductRef fbc:geneProduct="G_SLC7A9"/> <fbc:geneProductRef fbc:geneProduct="G_SLC38A5"/> - <fbc:geneProductRef fbc:geneProduct="G_SLC6A14"/> <fbc:geneProductRef fbc:geneProduct="G_SLC6A9"/> </fbc:or> </fbc:geneProductAssociation> @@ -14699,13 +14697,13 @@ </fbc:objective> </fbc:listOfObjectives> <fbc:listOfGeneProducts> - <fbc:geneProduct fbc:id="G_SLC16A3" fbc:name="G_SLC16A3" fbc:label="G_SLC16A3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000141526</p> - <p>HGNC ID: HGNC:10924</p> - <p>HGNC symbol: SLC16A3</p> - <p>entrez_id: 9123</p> + <fbc:geneProduct fbc:id="G_SLC16A7" fbc:name="G_SLC16A7" fbc:label="G_SLC16A7"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000118596</p> + <p>HGNC ID: HGNC:10928</p> + <p>HGNC symbol: SLC16A7</p> + <p>entrez_id: 9194</p> </html> </notes> </fbc:geneProduct> @@ -14719,13 +14717,43 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC16A7" fbc:name="G_SLC16A7" fbc:label="G_SLC16A7"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000118596</p> - <p>HGNC ID: HGNC:10928</p> - <p>HGNC symbol: SLC16A7</p> - <p>entrez_id: 9194</p> + <fbc:geneProduct fbc:id="G_SLC16A3" fbc:name="G_SLC16A3" fbc:label="G_SLC16A3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000141526</p> + <p>HGNC ID: HGNC:10924</p> + <p>HGNC symbol: SLC16A3</p> + <p>entrez_id: 9123</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GCK" fbc:name="G_GCK" fbc:label="G_GCK"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000106633</p> + <p>HGNC ID: HGNC:4195</p> + <p>HGNC symbol: GCK</p> + <p>entrez_id: 2645</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_HK3" fbc:name="G_HK3" fbc:label="G_HK3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000160883</p> + <p>HGNC ID: HGNC:4925</p> + <p>HGNC symbol: HK3</p> + <p>entrez_id: 3101</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_HK2" fbc:name="G_HK2" fbc:label="G_HK2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000159399</p> + <p>HGNC ID: HGNC:4923</p> + <p>HGNC symbol: HK2</p> + <p>entrez_id: 3099</p> </html> </notes> </fbc:geneProduct> @@ -14739,36 +14767,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HK3" fbc:name="G_HK3" fbc:label="G_HK3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000160883</p> - <p>HGNC ID: HGNC:4925</p> - <p>HGNC symbol: HK3</p> - <p>entrez_id: 3101</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_GCK" fbc:name="G_GCK" fbc:label="G_GCK"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000106633</p> - <p>HGNC ID: HGNC:4195</p> - <p>HGNC symbol: GCK</p> - <p>entrez_id: 2645</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HK2" fbc:name="G_HK2" fbc:label="G_HK2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000159399</p> - <p>HGNC ID: HGNC:4923</p> - <p>HGNC symbol: HK2</p> - <p>entrez_id: 3099</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_HK1" fbc:name="G_HK1" fbc:label="G_HK1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -14779,6 +14777,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_G6PC3" fbc:name="G_G6PC3" fbc:label="G_G6PC3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000141349</p> + <p>HGNC ID: HGNC:24861</p> + <p>HGNC symbol: G6PC3</p> + <p>entrez_id: 92579</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_G6PC1" fbc:name="G_G6PC1" fbc:label="G_G6PC1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -14799,16 +14807,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_G6PC3" fbc:name="G_G6PC3" fbc:label="G_G6PC3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000141349</p> - <p>HGNC ID: HGNC:24861</p> - <p>HGNC symbol: G6PC3</p> - <p>entrez_id: 92579</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GPI" fbc:name="G_GPI" fbc:label="G_GPI"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -14819,13 +14817,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PFKL" fbc:name="G_PFKL" fbc:label="G_PFKL"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000141959</p> - <p>HGNC ID: HGNC:8876</p> - <p>HGNC symbol: PFKL</p> - <p>entrez_id: 5211</p> + <fbc:geneProduct fbc:id="G_PFKP" fbc:name="G_PFKP" fbc:label="G_PFKP"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000067057</p> + <p>HGNC ID: HGNC:8878</p> + <p>HGNC symbol: PFKP</p> + <p>entrez_id: 5214</p> </html> </notes> </fbc:geneProduct> @@ -14839,13 +14837,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PFKP" fbc:name="G_PFKP" fbc:label="G_PFKP"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000067057</p> - <p>HGNC ID: HGNC:8878</p> - <p>HGNC symbol: PFKP</p> - <p>entrez_id: 5214</p> + <fbc:geneProduct fbc:id="G_PFKL" fbc:name="G_PFKL" fbc:label="G_PFKL"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000141959</p> + <p>HGNC ID: HGNC:8876</p> + <p>HGNC symbol: PFKL</p> + <p>entrez_id: 5211</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_FBP1" fbc:name="G_FBP1" fbc:label="G_FBP1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000165140</p> + <p>HGNC ID: HGNC:3606</p> + <p>HGNC symbol: FBP1</p> + <p>entrez_id: 2203</p> </html> </notes> </fbc:geneProduct> @@ -14859,26 +14867,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_FBP1" fbc:name="G_FBP1" fbc:label="G_FBP1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000165140</p> - <p>HGNC ID: HGNC:3606</p> - <p>HGNC symbol: FBP1</p> - <p>entrez_id: 2203</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ALDOC" fbc:name="G_ALDOC" fbc:label="G_ALDOC"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000109107</p> - <p>HGNC ID: HGNC:418</p> - <p>HGNC symbol: ALDOC</p> - <p>entrez_id: 230</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ALDOA" fbc:name="G_ALDOA" fbc:label="G_ALDOA"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -14899,6 +14887,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ALDOC" fbc:name="G_ALDOC" fbc:label="G_ALDOC"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000109107</p> + <p>HGNC ID: HGNC:418</p> + <p>HGNC symbol: ALDOC</p> + <p>entrez_id: 230</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_TPI1" fbc:name="G_TPI1" fbc:label="G_TPI1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -14949,6 +14947,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PGAM2" fbc:name="G_PGAM2" fbc:label="G_PGAM2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000164708</p> + <p>HGNC ID: HGNC:8889</p> + <p>HGNC symbol: PGAM2</p> + <p>entrez_id: 5224</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_BPGM" fbc:name="G_BPGM" fbc:label="G_BPGM"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -14969,16 +14977,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PGAM2" fbc:name="G_PGAM2" fbc:label="G_PGAM2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000164708</p> - <p>HGNC ID: HGNC:8889</p> - <p>HGNC symbol: PGAM2</p> - <p>entrez_id: 5224</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ENO2" fbc:name="G_ENO2" fbc:label="G_ENO2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15009,6 +15007,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PKLR" fbc:name="G_PKLR" fbc:label="G_PKLR"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000143627</p> + <p>HGNC ID: HGNC:9020</p> + <p>HGNC symbol: PKLR</p> + <p>entrez_id: 5313</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PKM" fbc:name="G_PKM" fbc:label="G_PKM"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15019,13 +15027,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PKLR" fbc:name="G_PKLR" fbc:label="G_PKLR"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000143627</p> - <p>HGNC ID: HGNC:9020</p> - <p>HGNC symbol: PKLR</p> - <p>entrez_id: 5313</p> + <fbc:geneProduct fbc:id="G_LDHA" fbc:name="G_LDHA" fbc:label="G_LDHA"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000134333</p> + <p>HGNC ID: HGNC:6535</p> + <p>HGNC symbol: LDHA</p> + <p>entrez_id: 3939</p> </html> </notes> </fbc:geneProduct> @@ -15039,13 +15047,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_UEVLD" fbc:name="G_UEVLD" fbc:label="G_UEVLD"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000151116</p> - <p>HGNC ID: HGNC:30866</p> - <p>HGNC symbol: UEVLD</p> - <p>entrez_id: 55293</p> + <fbc:geneProduct fbc:id="G_LDHB" fbc:name="G_LDHB" fbc:label="G_LDHB"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000111716</p> + <p>HGNC ID: HGNC:6541</p> + <p>HGNC symbol: LDHB</p> + <p>entrez_id: 3945</p> </html> </notes> </fbc:geneProduct> @@ -15059,26 +15067,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_LDHA" fbc:name="G_LDHA" fbc:label="G_LDHA"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000134333</p> - <p>HGNC ID: HGNC:6535</p> - <p>HGNC symbol: LDHA</p> - <p>entrez_id: 3939</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_LDHB" fbc:name="G_LDHB" fbc:label="G_LDHB"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000111716</p> - <p>HGNC ID: HGNC:6541</p> - <p>HGNC symbol: LDHB</p> - <p>entrez_id: 3945</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_LDHAL6A" fbc:name="G_LDHAL6A" fbc:label="G_LDHAL6A"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15089,6 +15077,26 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_UEVLD" fbc:name="G_UEVLD" fbc:label="G_UEVLD"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000151116</p> + <p>HGNC ID: HGNC:30866</p> + <p>HGNC symbol: UEVLD</p> + <p>entrez_id: 55293</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PRPS2" fbc:name="G_PRPS2" fbc:label="G_PRPS2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000101911</p> + <p>HGNC ID: HGNC:9465</p> + <p>HGNC symbol: PRPS2</p> + <p>entrez_id: 5634</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PRPS1" fbc:name="G_PRPS1" fbc:label="G_PRPS1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15099,16 +15107,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PRPS2" fbc:name="G_PRPS2" fbc:label="G_PRPS2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000101911</p> - <p>HGNC ID: HGNC:9465</p> - <p>HGNC symbol: PRPS2</p> - <p>entrez_id: 5634</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PRPS1L1" fbc:name="G_PRPS1L1" fbc:label="G_PRPS1L1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15129,6 +15127,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_H6PD" fbc:name="G_H6PD" fbc:label="G_H6PD"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000049239</p> + <p>HGNC ID: HGNC:4795</p> + <p>HGNC symbol: H6PD</p> + <p>entrez_id: 9563</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PGLS" fbc:name="G_PGLS" fbc:label="G_PGLS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15139,16 +15147,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_H6PD" fbc:name="G_H6PD" fbc:label="G_H6PD"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000049239</p> - <p>HGNC ID: HGNC:4795</p> - <p>HGNC symbol: H6PD</p> - <p>entrez_id: 9563</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PGD" fbc:name="G_PGD" fbc:label="G_PGD"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15169,6 +15167,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_TKTL1" fbc:name="G_TKTL1" fbc:label="G_TKTL1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000007350</p> + <p>HGNC ID: HGNC:11835</p> + <p>HGNC symbol: TKTL1</p> + <p>entrez_id: 8277</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_TKTL2" fbc:name="G_TKTL2" fbc:label="G_TKTL2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15189,13 +15197,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_TKTL1" fbc:name="G_TKTL1" fbc:label="G_TKTL1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000007350</p> - <p>HGNC ID: HGNC:11835</p> - <p>HGNC symbol: TKTL1</p> - <p>entrez_id: 8277</p> + <fbc:geneProduct fbc:id="G_RPEL1" fbc:name="G_RPEL1" fbc:label="G_RPEL1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000235376</p> + <p>HGNC ID: HGNC:45241</p> + <p>HGNC symbol: RPEL1</p> + <p>entrez_id: 729020</p> </html> </notes> </fbc:geneProduct> @@ -15209,16 +15217,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_RPEL1" fbc:name="G_RPEL1" fbc:label="G_RPEL1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000235376</p> - <p>HGNC ID: HGNC:45241</p> - <p>HGNC symbol: RPEL1</p> - <p>entrez_id: 729020</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_TALDO1" fbc:name="G_TALDO1" fbc:label="G_TALDO1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15229,6 +15227,26 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PDHX" fbc:name="G_PDHX" fbc:label="G_PDHX"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000110435</p> + <p>HGNC ID: HGNC:21350</p> + <p>HGNC symbol: PDHX</p> + <p>entrez_id: 8050</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PDHA2" fbc:name="G_PDHA2" fbc:label="G_PDHA2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000163114</p> + <p>HGNC ID: HGNC:8807</p> + <p>HGNC symbol: PDHA2</p> + <p>entrez_id: 5161</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_DLD" fbc:name="G_DLD" fbc:label="G_DLD"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15239,13 +15257,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PDHA2" fbc:name="G_PDHA2" fbc:label="G_PDHA2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000163114</p> - <p>HGNC ID: HGNC:8807</p> - <p>HGNC symbol: PDHA2</p> - <p>entrez_id: 5161</p> + <fbc:geneProduct fbc:id="G_PDHA1" fbc:name="G_PDHA1" fbc:label="G_PDHA1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000131828</p> + <p>HGNC ID: HGNC:8806</p> + <p>HGNC symbol: PDHA1</p> + <p>entrez_id: 5160</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_DLAT" fbc:name="G_DLAT" fbc:label="G_DLAT"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000150768</p> + <p>HGNC ID: HGNC:2896</p> + <p>HGNC symbol: DLAT</p> + <p>entrez_id: 1737</p> </html> </notes> </fbc:geneProduct> @@ -15259,36 +15287,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PDHA1" fbc:name="G_PDHA1" fbc:label="G_PDHA1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000131828</p> - <p>HGNC ID: HGNC:8806</p> - <p>HGNC symbol: PDHA1</p> - <p>entrez_id: 5160</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PDHX" fbc:name="G_PDHX" fbc:label="G_PDHX"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000110435</p> - <p>HGNC ID: HGNC:21350</p> - <p>HGNC symbol: PDHX</p> - <p>entrez_id: 8050</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_DLAT" fbc:name="G_DLAT" fbc:label="G_DLAT"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000150768</p> - <p>HGNC ID: HGNC:2896</p> - <p>HGNC symbol: DLAT</p> - <p>entrez_id: 1737</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PC" fbc:name="G_PC" fbc:label="G_PC"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15319,6 +15317,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ACO2" fbc:name="G_ACO2" fbc:label="G_ACO2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000100412</p> + <p>HGNC ID: HGNC:118</p> + <p>HGNC symbol: ACO2</p> + <p>entrez_id: 50</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ACO1" fbc:name="G_ACO1" fbc:label="G_ACO1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15329,16 +15337,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ACO2" fbc:name="G_ACO2" fbc:label="G_ACO2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000100412</p> - <p>HGNC ID: HGNC:118</p> - <p>HGNC symbol: ACO2</p> - <p>entrez_id: 50</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_IDH3G" fbc:name="G_IDH3G" fbc:label="G_IDH3G"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15349,6 +15347,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_IDH3A" fbc:name="G_IDH3A" fbc:label="G_IDH3A"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000166411</p> + <p>HGNC ID: HGNC:5384</p> + <p>HGNC symbol: IDH3A</p> + <p>entrez_id: 3419</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_IDH3B" fbc:name="G_IDH3B" fbc:label="G_IDH3B"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15359,16 +15367,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_IDH3A" fbc:name="G_IDH3A" fbc:label="G_IDH3A"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000166411</p> - <p>HGNC ID: HGNC:5384</p> - <p>HGNC symbol: IDH3A</p> - <p>entrez_id: 3419</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_IDH2" fbc:name="G_IDH2" fbc:label="G_IDH2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15379,6 +15377,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_OGDH" fbc:name="G_OGDH" fbc:label="G_OGDH"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000105953</p> + <p>HGNC ID: HGNC:8124</p> + <p>HGNC symbol: OGDH</p> + <p>entrez_id: 4967</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_DLST" fbc:name="G_DLST" fbc:label="G_DLST"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15389,16 +15397,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_OGDH" fbc:name="G_OGDH" fbc:label="G_OGDH"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000105953</p> - <p>HGNC ID: HGNC:8124</p> - <p>HGNC symbol: OGDH</p> - <p>entrez_id: 4967</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SUCLG1" fbc:name="G_SUCLG1" fbc:label="G_SUCLG1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15519,6 +15517,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MDH1" fbc:name="G_MDH1" fbc:label="G_MDH1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000014641</p> + <p>HGNC ID: HGNC:6970</p> + <p>HGNC symbol: MDH1</p> + <p>entrez_id: 4190</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_MDH1B" fbc:name="G_MDH1B" fbc:label="G_MDH1B"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15529,16 +15537,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MDH1" fbc:name="G_MDH1" fbc:label="G_MDH1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000014641</p> - <p>HGNC ID: HGNC:6970</p> - <p>HGNC symbol: MDH1</p> - <p>entrez_id: 4190</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC25A11" fbc:name="G_SLC25A11" fbc:label="G_SLC25A11"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15569,6 +15567,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_LHPP" fbc:name="G_LHPP" fbc:label="G_LHPP"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000107902</p> + <p>HGNC ID: HGNC:30042</p> + <p>HGNC symbol: LHPP</p> + <p>entrez_id: 64077</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PPA1" fbc:name="G_PPA1" fbc:label="G_PPA1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15579,23 +15587,153 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_LHPP" fbc:name="G_LHPP" fbc:label="G_LHPP"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000107902</p> - <p>HGNC ID: HGNC:30042</p> - <p>HGNC symbol: LHPP</p> - <p>entrez_id: 64077</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFA10" fbc:name="G_NDUFA10" fbc:label="G_NDUFA10"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000130414</p> - <p>HGNC ID: HGNC:7684</p> - <p>HGNC symbol: NDUFA10</p> - <p>entrez_id: 4705</p> + <fbc:geneProduct fbc:id="G_NDUFS3" fbc:name="G_NDUFS3" fbc:label="G_NDUFS3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000213619</p> + <p>HGNC ID: HGNC:7710</p> + <p>HGNC symbol: NDUFS3</p> + <p>entrez_id: 4722</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB6" fbc:name="G_NDUFB6" fbc:label="G_NDUFB6"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000165264</p> + <p>HGNC ID: HGNC:7701</p> + <p>HGNC symbol: NDUFB6</p> + <p>entrez_id: 4712</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFV2" fbc:name="G_NDUFV2" fbc:label="G_NDUFV2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000178127</p> + <p>HGNC ID: HGNC:7717</p> + <p>HGNC symbol: NDUFV2</p> + <p>entrez_id: 4729</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB3" fbc:name="G_NDUFB3" fbc:label="G_NDUFB3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000119013</p> + <p>HGNC ID: HGNC:7698</p> + <p>HGNC symbol: NDUFB3</p> + <p>entrez_id: 4709</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB9" fbc:name="G_NDUFB9" fbc:label="G_NDUFB9"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000147684</p> + <p>HGNC ID: HGNC:7704</p> + <p>HGNC symbol: NDUFB9</p> + <p>entrez_id: 4715</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFAB1" fbc:name="G_NDUFAB1" fbc:label="G_NDUFAB1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000004779</p> + <p>HGNC ID: HGNC:7694</p> + <p>HGNC symbol: NDUFAB1</p> + <p>entrez_id: 4706</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFA1" fbc:name="G_NDUFA1" fbc:label="G_NDUFA1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000125356</p> + <p>HGNC ID: HGNC:7683</p> + <p>HGNC symbol: NDUFA1</p> + <p>entrez_id: 4694</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFA9" fbc:name="G_NDUFA9" fbc:label="G_NDUFA9"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000139180</p> + <p>HGNC ID: HGNC:7693</p> + <p>HGNC symbol: NDUFA9</p> + <p>entrez_id: 4704</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFS1" fbc:name="G_NDUFS1" fbc:label="G_NDUFS1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000023228</p> + <p>HGNC ID: HGNC:7707</p> + <p>HGNC symbol: NDUFS1</p> + <p>entrez_id: 4719</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFA11" fbc:name="G_NDUFA11" fbc:label="G_NDUFA11"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000174886</p> + <p>HGNC ID: HGNC:20371</p> + <p>HGNC symbol: NDUFA11</p> + <p>entrez_id: 126328</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB11" fbc:name="G_NDUFB11" fbc:label="G_NDUFB11"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000147123</p> + <p>HGNC ID: HGNC:20372</p> + <p>HGNC symbol: NDUFB11</p> + <p>entrez_id: 54539</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB7" fbc:name="G_NDUFB7" fbc:label="G_NDUFB7"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000099795</p> + <p>HGNC ID: HGNC:7702</p> + <p>HGNC symbol: NDUFB7</p> + <p>entrez_id: 4713</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFA8" fbc:name="G_NDUFA8" fbc:label="G_NDUFA8"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000119421</p> + <p>HGNC ID: HGNC:7692</p> + <p>HGNC symbol: NDUFA8</p> + <p>entrez_id: 4702</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFA2" fbc:name="G_NDUFA2" fbc:label="G_NDUFA2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000131495</p> + <p>HGNC ID: HGNC:7685</p> + <p>HGNC symbol: NDUFA2</p> + <p>entrez_id: 4695</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFS8" fbc:name="G_NDUFS8" fbc:label="G_NDUFS8"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000110717</p> + <p>HGNC ID: HGNC:7715</p> + <p>HGNC symbol: NDUFS8</p> + <p>entrez_id: 4728</p> </html> </notes> </fbc:geneProduct> @@ -15609,16 +15747,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFA2" fbc:name="G_NDUFA2" fbc:label="G_NDUFA2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000131495</p> - <p>HGNC ID: HGNC:7685</p> - <p>HGNC symbol: NDUFA2</p> - <p>entrez_id: 4695</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_NDUFS7" fbc:name="G_NDUFS7" fbc:label="G_NDUFS7"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -15629,23 +15757,33 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFA8" fbc:name="G_NDUFA8" fbc:label="G_NDUFA8"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000119421</p> - <p>HGNC ID: HGNC:7692</p> - <p>HGNC symbol: NDUFA8</p> - <p>entrez_id: 4702</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFV2" fbc:name="G_NDUFV2" fbc:label="G_NDUFV2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000178127</p> - <p>HGNC ID: HGNC:7717</p> - <p>HGNC symbol: NDUFV2</p> - <p>entrez_id: 4729</p> + <fbc:geneProduct fbc:id="G_MT__45__ND4" fbc:name="G_MT__45__ND4" fbc:label="G_MT__45__ND4"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000198886</p> + <p>HGNC ID: HGNC:7459</p> + <p>HGNC symbol: MT-ND4</p> + <p>entrez_id: 4538</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB2" fbc:name="G_NDUFB2" fbc:label="G_NDUFB2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000090266</p> + <p>HGNC ID: HGNC:7697</p> + <p>HGNC symbol: NDUFB2</p> + <p>entrez_id: 4708</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFS2" fbc:name="G_NDUFS2" fbc:label="G_NDUFS2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000158864</p> + <p>HGNC ID: HGNC:7708</p> + <p>HGNC symbol: NDUFS2</p> + <p>entrez_id: 4720</p> </html> </notes> </fbc:geneProduct> @@ -15659,43 +15797,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MT__45__ND2" fbc:name="G_MT__45__ND2" fbc:label="G_MT__45__ND2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198763</p> - <p>HGNC ID: HGNC:7456</p> - <p>HGNC symbol: MT-ND2</p> - <p>entrez_id: 4536</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFB6" fbc:name="G_NDUFB6" fbc:label="G_NDUFB6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000165264</p> - <p>HGNC ID: HGNC:7701</p> - <p>HGNC symbol: NDUFB6</p> - <p>entrez_id: 4712</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFA5" fbc:name="G_NDUFA5" fbc:label="G_NDUFA5"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000128609</p> - <p>HGNC ID: HGNC:7688</p> - <p>HGNC symbol: NDUFA5</p> - <p>entrez_id: 4698</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFB10" fbc:name="G_NDUFB10" fbc:label="G_NDUFB10"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000140990</p> - <p>HGNC ID: HGNC:7696</p> - <p>HGNC symbol: NDUFB10</p> - <p>entrez_id: 4716</p> + <fbc:geneProduct fbc:id="G_NDUFS5" fbc:name="G_NDUFS5" fbc:label="G_NDUFS5"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000168653</p> + <p>HGNC ID: HGNC:7712</p> + <p>HGNC symbol: NDUFS5</p> + <p>entrez_id: 4725</p> </html> </notes> </fbc:geneProduct> @@ -15709,13 +15817,133 @@ </html> </notes> </fbc:geneProduct> - 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xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000212907</p> + <p>HGNC ID: HGNC:7460</p> + <p>HGNC symbol: MT-ND4L</p> + <p>entrez_id: 4539</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB1" fbc:name="G_NDUFB1" fbc:label="G_NDUFB1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000183648</p> + <p>HGNC ID: HGNC:7695</p> + <p>HGNC symbol: NDUFB1</p> + <p>entrez_id: 4707</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFA5" fbc:name="G_NDUFA5" fbc:label="G_NDUFA5"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000128609</p> + <p>HGNC ID: HGNC:7688</p> + <p>HGNC symbol: NDUFA5</p> + <p>entrez_id: 4698</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MT__45__ND1" fbc:name="G_MT__45__ND1" fbc:label="G_MT__45__ND1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000198888</p> + <p>HGNC ID: HGNC:7455</p> + <p>HGNC symbol: 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fbc:name="G_NDUFB8" fbc:label="G_NDUFB8"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000166136</p> + <p>HGNC ID: HGNC:7703</p> + <p>HGNC symbol: NDUFB8</p> + <p>entrez_id: 4714</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MT__45__ND2" fbc:name="G_MT__45__ND2" fbc:label="G_MT__45__ND2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000198763</p> + <p>HGNC ID: HGNC:7456</p> + <p>HGNC symbol: MT-ND2</p> + <p>entrez_id: 4536</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFB5" fbc:name="G_NDUFB5" fbc:label="G_NDUFB5"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000136521</p> + <p>HGNC ID: HGNC:7700</p> + <p>HGNC symbol: NDUFB5</p> + <p>entrez_id: 4711</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NDUFA13" fbc:name="G_NDUFA13" fbc:label="G_NDUFA13"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000186010</p> + <p>HGNC ID: HGNC:17194</p> + <p>HGNC symbol: NDUFA13</p> + <p>entrez_id: 51079</p> </html> </notes> </fbc:geneProduct> @@ -15729,36 +15957,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFA11" fbc:name="G_NDUFA11" fbc:label="G_NDUFA11"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000174886</p> - <p>HGNC ID: HGNC:20371</p> - <p>HGNC symbol: NDUFA11</p> - <p>entrez_id: 126328</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFB1" fbc:name="G_NDUFB1" fbc:label="G_NDUFB1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000183648</p> - <p>HGNC ID: HGNC:7695</p> - <p>HGNC symbol: NDUFB1</p> - <p>entrez_id: 4707</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFB5" fbc:name="G_NDUFB5" fbc:label="G_NDUFB5"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000136521</p> - <p>HGNC ID: HGNC:7700</p> - <p>HGNC symbol: 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xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198786</p> - <p>HGNC ID: HGNC:7461</p> - <p>HGNC symbol: MT-ND5</p> - <p>entrez_id: 4540</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFS2" fbc:name="G_NDUFS2" fbc:label="G_NDUFS2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000158864</p> - <p>HGNC ID: HGNC:7708</p> - <p>HGNC symbol: NDUFS2</p> - <p>entrez_id: 4720</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MT__45__ND1" fbc:name="G_MT__45__ND1" fbc:label="G_MT__45__ND1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198888</p> - <p>HGNC ID: HGNC:7455</p> - <p>HGNC symbol: MT-ND1</p> - <p>entrez_id: 4535</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NDUFB9" fbc:name="G_NDUFB9" fbc:label="G_NDUFB9"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000147684</p> - <p>HGNC ID: HGNC:7704</p> - <p>HGNC symbol: 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<notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000023228</p> - <p>HGNC ID: HGNC:7707</p> - <p>HGNC symbol: NDUFS1</p> - <p>entrez_id: 4719</p> + <fbc:geneProduct fbc:id="G_ETFDH" fbc:name="G_ETFDH" fbc:label="G_ETFDH"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000171503</p> + <p>HGNC ID: HGNC:3483</p> + <p>HGNC symbol: ETFDH</p> + <p>entrez_id: 2110</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ETFB" fbc:name="G_ETFB" fbc:label="G_ETFB"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000105379</p> + <p>HGNC ID: HGNC:3482</p> + <p>HGNC symbol: ETFB</p> + <p>entrez_id: 2109</p> </html> </notes> </fbc:geneProduct> @@ -15989,66 +16007,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ETFB" fbc:name="G_ETFB" fbc:label="G_ETFB"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000105379</p> - <p>HGNC ID: HGNC:3482</p> - <p>HGNC symbol: 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fbc:label="G_CYC1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000179091</p> - <p>HGNC ID: HGNC:2579</p> - <p>HGNC symbol: CYC1</p> - <p>entrez_id: 1537</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_UQCRC1" fbc:name="G_UQCRC1" fbc:label="G_UQCRC1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000010256</p> - <p>HGNC ID: HGNC:12585</p> - <p>HGNC symbol: UQCRC1</p> - <p>entrez_id: 7384</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_UQCRQ" fbc:name="G_UQCRQ" fbc:label="G_UQCRQ"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16059,36 +16017,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_UQCR10" fbc:name="G_UQCR10" fbc:label="G_UQCR10"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000184076</p> - <p>HGNC ID: HGNC:30863</p> - <p>HGNC symbol: UQCR10</p> - <p>entrez_id: 29796</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_UQCR11" fbc:name="G_UQCR11" fbc:label="G_UQCR11"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000127540</p> - <p>HGNC ID: HGNC:30862</p> - <p>HGNC symbol: UQCR11</p> - <p>entrez_id: 10975</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MT__45__CYB" fbc:name="G_MT__45__CYB" fbc:label="G_MT__45__CYB"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198727</p> - <p>HGNC ID: HGNC:7427</p> - <p>HGNC symbol: MT-CYB</p> - <p>entrez_id: 4519</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_UQCRB" fbc:name="G_UQCRB" fbc:label="G_UQCRB"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16109,23 +16037,113 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MT__45__CO2" fbc:name="G_MT__45__CO2" fbc:label="G_MT__45__CO2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198712</p> - <p>HGNC ID: HGNC:7421</p> - 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fbc:label="G_UQCRC2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000140740</p> + <p>HGNC ID: HGNC:12586</p> + <p>HGNC symbol: UQCRC2</p> + <p>entrez_id: 7385</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_UQCRC1" fbc:name="G_UQCRC1" fbc:label="G_UQCRC1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000010256</p> + <p>HGNC ID: HGNC:12585</p> + <p>HGNC symbol: UQCRC1</p> + <p>entrez_id: 7384</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_UQCRFS1" fbc:name="G_UQCRFS1" fbc:label="G_UQCRFS1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000169021</p> + <p>HGNC ID: HGNC:12587</p> + <p>HGNC symbol: UQCRFS1</p> + <p>entrez_id: 7386</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_UQCR11" fbc:name="G_UQCR11" fbc:label="G_UQCR11"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000127540</p> + <p>HGNC ID: HGNC:30862</p> + <p>HGNC symbol: UQCR11</p> + <p>entrez_id: 10975</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CYC1" fbc:name="G_CYC1" fbc:label="G_CYC1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000179091</p> + <p>HGNC ID: HGNC:2579</p> + <p>HGNC symbol: CYC1</p> + <p>entrez_id: 1537</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX4I2" fbc:name="G_COX4I2" fbc:label="G_COX4I2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000131055</p> + <p>HGNC ID: HGNC:16232</p> + <p>HGNC symbol: COX4I2</p> + <p>entrez_id: 84701</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX6C" fbc:name="G_COX6C" fbc:label="G_COX6C"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000164919</p> + <p>HGNC ID: HGNC:2285</p> + <p>HGNC symbol: COX6C</p> + <p>entrez_id: 1345</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX6B1" fbc:name="G_COX6B1" fbc:label="G_COX6B1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000126267</p> + <p>HGNC ID: HGNC:2280</p> + <p>HGNC symbol: COX6B1</p> + <p>entrez_id: 1340</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MT__45__CO3" fbc:name="G_MT__45__CO3" fbc:label="G_MT__45__CO3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000198938</p> + <p>HGNC ID: HGNC:7422</p> + <p>HGNC symbol: MT-CO3</p> + <p>entrez_id: 4514</p> </html> </notes> </fbc:geneProduct> @@ -16139,56 +16157,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX6A1" fbc:name="G_COX6A1" fbc:label="G_COX6A1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000111775</p> - <p>HGNC ID: HGNC:2277</p> - <p>HGNC symbol: COX6A1</p> - <p>entrez_id: 1337</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX4I2" fbc:name="G_COX4I2" fbc:label="G_COX4I2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000131055</p> - <p>HGNC ID: HGNC:16232</p> - <p>HGNC symbol: COX4I2</p> - <p>entrez_id: 84701</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX7B2" fbc:name="G_COX7B2" fbc:label="G_COX7B2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000170516</p> - <p>HGNC ID: HGNC:24381</p> - <p>HGNC symbol: COX7B2</p> - <p>entrez_id: 170712</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX7C" fbc:name="G_COX7C" fbc:label="G_COX7C"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000127184</p> - <p>HGNC ID: HGNC:2292</p> - <p>HGNC symbol: COX7C</p> - <p>entrez_id: 1350</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX6B1" fbc:name="G_COX6B1" fbc:label="G_COX6B1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000126267</p> - <p>HGNC ID: HGNC:2280</p> - <p>HGNC symbol: COX6B1</p> - <p>entrez_id: 1340</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_COX7A2" fbc:name="G_COX7A2" fbc:label="G_COX7A2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16199,13 +16167,53 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MT__45__CO1" fbc:name="G_MT__45__CO1" fbc:label="G_MT__45__CO1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198804</p> - <p>HGNC ID: HGNC:7419</p> - <p>HGNC symbol: MT-CO1</p> - <p>entrez_id: 4512</p> + <fbc:geneProduct fbc:id="G_MT__45__CO2" fbc:name="G_MT__45__CO2" fbc:label="G_MT__45__CO2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000198712</p> + <p>HGNC ID: HGNC:7421</p> + <p>HGNC symbol: MT-CO2</p> + <p>entrez_id: 4513</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX5B" fbc:name="G_COX5B" fbc:label="G_COX5B"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000135940</p> + <p>HGNC ID: HGNC:2269</p> + <p>HGNC symbol: COX5B</p> + <p>entrez_id: 1329</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX7B2" fbc:name="G_COX7B2" fbc:label="G_COX7B2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000170516</p> + <p>HGNC ID: HGNC:24381</p> + <p>HGNC symbol: COX7B2</p> + <p>entrez_id: 170712</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX7B" fbc:name="G_COX7B" fbc:label="G_COX7B"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000131174</p> + <p>HGNC ID: HGNC:2291</p> + <p>HGNC symbol: COX7B</p> + <p>entrez_id: 1349</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX6A1" fbc:name="G_COX6A1" fbc:label="G_COX6A1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000111775</p> + <p>HGNC ID: HGNC:2277</p> + <p>HGNC symbol: COX6A1</p> + <p>entrez_id: 1337</p> </html> </notes> </fbc:geneProduct> @@ -16219,23 +16227,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX7B" fbc:name="G_COX7B" fbc:label="G_COX7B"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000131174</p> - <p>HGNC ID: HGNC:2291</p> - <p>HGNC symbol: COX7B</p> - <p>entrez_id: 1349</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX6C" fbc:name="G_COX6C" fbc:label="G_COX6C"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000164919</p> - <p>HGNC ID: HGNC:2285</p> - <p>HGNC symbol: COX6C</p> - <p>entrez_id: 1345</p> + <fbc:geneProduct fbc:id="G_COX8C" fbc:name="G_COX8C" fbc:label="G_COX8C"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000187581</p> + <p>HGNC ID: HGNC:24382</p> + <p>HGNC symbol: COX8C</p> + <p>entrez_id: 341947</p> </html> </notes> </fbc:geneProduct> @@ -16249,6 +16247,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX8A" fbc:name="G_COX8A" fbc:label="G_COX8A"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000176340</p> + <p>HGNC ID: HGNC:2294</p> + <p>HGNC symbol: COX8A</p> + <p>entrez_id: 1351</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_COX5A" fbc:name="G_COX5A" fbc:label="G_COX5A"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16259,43 +16267,153 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX8C" fbc:name="G_COX8C" fbc:label="G_COX8C"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000187581</p> - <p>HGNC ID: HGNC:24382</p> - <p>HGNC symbol: COX8C</p> - <p>entrez_id: 341947</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_COX8A" fbc:name="G_COX8A" fbc:label="G_COX8A"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000176340</p> - <p>HGNC ID: HGNC:2294</p> - <p>HGNC symbol: COX8A</p> - <p>entrez_id: 1351</p> - </html> - </notes> - 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xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000131143</p> + <p>HGNC ID: HGNC:2265</p> + <p>HGNC symbol: COX4I1</p> + <p>entrez_id: 1327</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_COX7C" fbc:name="G_COX7C" fbc:label="G_COX7C"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000127184</p> + <p>HGNC ID: HGNC:2292</p> + <p>HGNC symbol: COX7C</p> + <p>entrez_id: 1350</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5F1E" fbc:name="G_ATP5F1E" fbc:label="G_ATP5F1E"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000124172</p> + <p>HGNC ID: HGNC:838</p> + <p>HGNC symbol: ATP5F1E</p> + <p>entrez_id: 514</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5F1C" fbc:name="G_ATP5F1C" fbc:label="G_ATP5F1C"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000165629</p> + <p>HGNC ID: HGNC:833</p> + <p>HGNC symbol: ATP5F1C</p> + <p>entrez_id: 509</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MC2" fbc:name="G_ATP5MC2" fbc:label="G_ATP5MC2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000135390</p> + <p>HGNC ID: HGNC:842</p> + <p>HGNC symbol: ATP5MC2</p> + <p>entrez_id: 517</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MT__45__ATP6" fbc:name="G_MT__45__ATP6" fbc:label="G_MT__45__ATP6"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000198899</p> + <p>HGNC ID: HGNC:7414</p> + <p>HGNC symbol: MT-ATP6</p> + <p>entrez_id: 4508</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5F1D" fbc:name="G_ATP5F1D" fbc:label="G_ATP5F1D"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000099624</p> + <p>HGNC ID: HGNC:837</p> + <p>HGNC symbol: ATP5F1D</p> + <p>entrez_id: 513</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MC3" fbc:name="G_ATP5MC3" fbc:label="G_ATP5MC3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000154518</p> + <p>HGNC ID: HGNC:843</p> + <p>HGNC symbol: ATP5MC3</p> + <p>entrez_id: 518</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5ME" fbc:name="G_ATP5ME" fbc:label="G_ATP5ME"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000169020</p> + <p>HGNC ID: HGNC:846</p> + <p>HGNC symbol: ATP5ME</p> + <p>entrez_id: 521</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5F1A" fbc:name="G_ATP5F1A" fbc:label="G_ATP5F1A"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000152234</p> + <p>HGNC ID: HGNC:823</p> + <p>HGNC symbol: ATP5F1A</p> + <p>entrez_id: 498</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MT__45__ATP8" fbc:name="G_MT__45__ATP8" fbc:label="G_MT__45__ATP8"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000228253</p> + <p>HGNC ID: HGNC:7415</p> + <p>HGNC symbol: MT-ATP8</p> + <p>entrez_id: 4509</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MG" fbc:name="G_ATP5MG" fbc:label="G_ATP5MG"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167283</p> + <p>HGNC ID: HGNC:14247</p> + <p>HGNC symbol: ATP5MG</p> + <p>entrez_id: 10632</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5MC1" fbc:name="G_ATP5MC1" fbc:label="G_ATP5MC1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000159199</p> + <p>HGNC ID: HGNC:841</p> + <p>HGNC symbol: ATP5MC1</p> + <p>entrez_id: 516</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5PO" fbc:name="G_ATP5PO" fbc:label="G_ATP5PO"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000241837</p> + <p>HGNC ID: HGNC:850</p> + <p>HGNC symbol: ATP5PO</p> + <p>entrez_id: 539</p> </html> </notes> </fbc:geneProduct> @@ -16319,13 +16437,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5ME" fbc:name="G_ATP5ME" fbc:label="G_ATP5ME"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000169020</p> - <p>HGNC ID: HGNC:846</p> - <p>HGNC symbol: ATP5ME</p> - <p>entrez_id: 521</p> + <fbc:geneProduct fbc:id="G_ATP5MF" fbc:name="G_ATP5MF" fbc:label="G_ATP5MF"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000241468</p> + <p>HGNC ID: HGNC:848</p> + <p>HGNC symbol: ATP5MF</p> + <p>entrez_id: 9551</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ATP5PB" fbc:name="G_ATP5PB" fbc:label="G_ATP5PB"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000116459</p> + <p>HGNC ID: HGNC:840</p> + <p>HGNC symbol: ATP5PB</p> + <p>entrez_id: 515</p> </html> </notes> </fbc:geneProduct> @@ -16339,136 +16467,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5F1C" fbc:name="G_ATP5F1C" fbc:label="G_ATP5F1C"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000165629</p> - <p>HGNC ID: HGNC:833</p> - <p>HGNC symbol: ATP5F1C</p> - <p>entrez_id: 509</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5F1D" fbc:name="G_ATP5F1D" fbc:label="G_ATP5F1D"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000099624</p> - <p>HGNC ID: HGNC:837</p> - <p>HGNC symbol: ATP5F1D</p> - <p>entrez_id: 513</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5MC2" fbc:name="G_ATP5MC2" fbc:label="G_ATP5MC2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000135390</p> - <p>HGNC ID: HGNC:842</p> - <p>HGNC symbol: ATP5MC2</p> - <p>entrez_id: 517</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5MF" fbc:name="G_ATP5MF" fbc:label="G_ATP5MF"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000241468</p> - <p>HGNC ID: HGNC:848</p> - <p>HGNC symbol: ATP5MF</p> - <p>entrez_id: 9551</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5F1A" fbc:name="G_ATP5F1A" fbc:label="G_ATP5F1A"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000152234</p> - <p>HGNC ID: HGNC:823</p> - <p>HGNC symbol: ATP5F1A</p> - <p>entrez_id: 498</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5PB" fbc:name="G_ATP5PB" fbc:label="G_ATP5PB"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000116459</p> - <p>HGNC ID: HGNC:840</p> - <p>HGNC symbol: ATP5PB</p> - <p>entrez_id: 515</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5MC3" fbc:name="G_ATP5MC3" fbc:label="G_ATP5MC3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000154518</p> - <p>HGNC ID: HGNC:843</p> - <p>HGNC symbol: ATP5MC3</p> - <p>entrez_id: 518</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5PO" fbc:name="G_ATP5PO" fbc:label="G_ATP5PO"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000241837</p> - <p>HGNC ID: HGNC:850</p> - <p>HGNC symbol: ATP5PO</p> - <p>entrez_id: 539</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5F1E" fbc:name="G_ATP5F1E" fbc:label="G_ATP5F1E"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000124172</p> - <p>HGNC ID: HGNC:838</p> - <p>HGNC symbol: ATP5F1E</p> - <p>entrez_id: 514</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5MC1" fbc:name="G_ATP5MC1" fbc:label="G_ATP5MC1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000159199</p> - <p>HGNC ID: HGNC:841</p> - <p>HGNC symbol: ATP5MC1</p> - <p>entrez_id: 516</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MT__45__ATP6" fbc:name="G_MT__45__ATP6" fbc:label="G_MT__45__ATP6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198899</p> - <p>HGNC ID: HGNC:7414</p> - <p>HGNC symbol: MT-ATP6</p> - <p>entrez_id: 4508</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MT__45__ATP8" fbc:name="G_MT__45__ATP8" fbc:label="G_MT__45__ATP8"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000228253</p> - <p>HGNC ID: HGNC:7415</p> - <p>HGNC symbol: MT-ATP8</p> - <p>entrez_id: 4509</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ATP5MG" fbc:name="G_ATP5MG" fbc:label="G_ATP5MG"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167283</p> - <p>HGNC ID: HGNC:14247</p> - <p>HGNC symbol: ATP5MG</p> - <p>entrez_id: 10632</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GCLC" fbc:name="G_GCLC" fbc:label="G_GCLC"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16509,13 +16507,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PRDX1" fbc:name="G_PRDX1" fbc:label="G_PRDX1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000117450</p> - <p>HGNC ID: HGNC:9352</p> - <p>HGNC symbol: PRDX1</p> - <p>entrez_id: 5052</p> + <fbc:geneProduct fbc:id="G_PRDX2" fbc:name="G_PRDX2" fbc:label="G_PRDX2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167815</p> + <p>HGNC ID: HGNC:9353</p> + <p>HGNC symbol: PRDX2</p> + <p>entrez_id: 7001</p> </html> </notes> </fbc:geneProduct> @@ -16529,6 +16527,26 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GPX4" fbc:name="G_GPX4" fbc:label="G_GPX4"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167468</p> + <p>HGNC ID: HGNC:4556</p> + <p>HGNC symbol: GPX4</p> + <p>entrez_id: 2879</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PRDX1" fbc:name="G_PRDX1" fbc:label="G_PRDX1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000117450</p> + <p>HGNC ID: HGNC:9352</p> + <p>HGNC symbol: PRDX1</p> + <p>entrez_id: 5052</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GPX1" fbc:name="G_GPX1" fbc:label="G_GPX1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16539,26 +16557,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PRDX2" fbc:name="G_PRDX2" fbc:label="G_PRDX2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167815</p> - <p>HGNC ID: HGNC:9353</p> - <p>HGNC symbol: PRDX2</p> - <p>entrez_id: 7001</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_GPX4" fbc:name="G_GPX4" fbc:label="G_GPX4"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167468</p> - <p>HGNC ID: HGNC:4556</p> - <p>HGNC symbol: GPX4</p> - <p>entrez_id: 2879</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PRDX3" fbc:name="G_PRDX3" fbc:label="G_PRDX3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16629,6 +16627,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC25A6" fbc:name="G_SLC25A6" fbc:label="G_SLC25A6"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000169100</p> + <p>HGNC ID: HGNC:10992</p> + <p>HGNC symbol: SLC25A6</p> + <p>entrez_id: 293</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC25A5" fbc:name="G_SLC25A5" fbc:label="G_SLC25A5"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16639,16 +16647,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC25A6" fbc:name="G_SLC25A6" fbc:label="G_SLC25A6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000169100</p> - <p>HGNC ID: HGNC:10992</p> - <p>HGNC symbol: SLC25A6</p> - <p>entrez_id: 293</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_NNT" fbc:name="G_NNT" fbc:label="G_NNT"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16669,13 +16667,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CA3" fbc:name="G_CA3" fbc:label="G_CA3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000164879</p> - <p>HGNC ID: HGNC:1374</p> - <p>HGNC symbol: CA3</p> - <p>entrez_id: 761</p> + <fbc:geneProduct fbc:id="G_CA13" fbc:name="G_CA13" fbc:label="G_CA13"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000185015</p> + <p>HGNC ID: HGNC:14914</p> + <p>HGNC symbol: CA13</p> + <p>entrez_id: 377677</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CA4" fbc:name="G_CA4" fbc:label="G_CA4"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167434</p> + <p>HGNC ID: HGNC:1375</p> + <p>HGNC symbol: CA4</p> + <p>entrez_id: 762</p> </html> </notes> </fbc:geneProduct> @@ -16689,33 +16697,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CA14" fbc:name="G_CA14" fbc:label="G_CA14"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000118298</p> - <p>HGNC ID: HGNC:1372</p> - <p>HGNC symbol: CA14</p> - <p>entrez_id: 23632</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CA13" fbc:name="G_CA13" fbc:label="G_CA13"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000185015</p> - <p>HGNC ID: HGNC:14914</p> - <p>HGNC symbol: CA13</p> - <p>entrez_id: 377677</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CA12" fbc:name="G_CA12" fbc:label="G_CA12"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000074410</p> - <p>HGNC ID: HGNC:1371</p> - <p>HGNC symbol: CA12</p> - <p>entrez_id: 771</p> + <fbc:geneProduct fbc:id="G_CA3" fbc:name="G_CA3" fbc:label="G_CA3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000164879</p> + <p>HGNC ID: HGNC:1374</p> + <p>HGNC symbol: CA3</p> + <p>entrez_id: 761</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CA2" fbc:name="G_CA2" fbc:label="G_CA2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000104267</p> + <p>HGNC ID: HGNC:1373</p> + <p>HGNC symbol: CA2</p> + <p>entrez_id: 760</p> </html> </notes> </fbc:geneProduct> @@ -16739,26 +16737,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CA2" fbc:name="G_CA2" fbc:label="G_CA2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000104267</p> - <p>HGNC ID: HGNC:1373</p> - <p>HGNC symbol: CA2</p> - <p>entrez_id: 760</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CA4" fbc:name="G_CA4" fbc:label="G_CA4"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167434</p> - <p>HGNC ID: HGNC:1375</p> - <p>HGNC symbol: CA4</p> - <p>entrez_id: 762</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_CA6" fbc:name="G_CA6" fbc:label="G_CA6"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16769,6 +16747,36 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CA14" fbc:name="G_CA14" fbc:label="G_CA14"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000118298</p> + <p>HGNC ID: HGNC:1372</p> + <p>HGNC symbol: CA14</p> + <p>entrez_id: 23632</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CA12" fbc:name="G_CA12" fbc:label="G_CA12"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000074410</p> + <p>HGNC ID: HGNC:1371</p> + <p>HGNC symbol: CA12</p> + <p>entrez_id: 771</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CA5B" fbc:name="G_CA5B" fbc:label="G_CA5B"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000169239</p> + <p>HGNC ID: HGNC:1378</p> + <p>HGNC symbol: CA5B</p> + <p>entrez_id: 11238</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_CA5A" fbc:name="G_CA5A" fbc:label="G_CA5A"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16779,16 +16787,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CA5B" fbc:name="G_CA5B" fbc:label="G_CA5B"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000169239</p> - <p>HGNC ID: HGNC:1378</p> - <p>HGNC symbol: CA5B</p> - <p>entrez_id: 11238</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GLS" fbc:name="G_GLS" fbc:label="G_GLS"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16799,6 +16797,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GLUL" fbc:name="G_GLUL" fbc:label="G_GLUL"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000135821</p> + <p>HGNC ID: HGNC:4341</p> + <p>HGNC symbol: GLUL</p> + <p>entrez_id: 2752</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_LGSN" fbc:name="G_LGSN" fbc:label="G_LGSN"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16809,16 +16817,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_GLUL" fbc:name="G_GLUL" fbc:label="G_GLUL"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000135821</p> - <p>HGNC ID: HGNC:4341</p> - <p>HGNC symbol: GLUL</p> - <p>entrez_id: 2752</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC25A22" fbc:name="G_SLC25A22" fbc:label="G_SLC25A22"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16969,6 +16967,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_RRM1" fbc:name="G_RRM1" fbc:label="G_RRM1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167325</p> + <p>HGNC ID: HGNC:10451</p> + <p>HGNC symbol: RRM1</p> + <p>entrez_id: 6240</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_RRM2" fbc:name="G_RRM2" fbc:label="G_RRM2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -16979,16 +16987,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_RRM1" fbc:name="G_RRM1" fbc:label="G_RRM1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167325</p> - <p>HGNC ID: HGNC:10451</p> - <p>HGNC symbol: RRM1</p> - <p>entrez_id: 6240</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_RRM2B" fbc:name="G_RRM2B" fbc:label="G_RRM2B"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17099,6 +17097,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_NME3" fbc:name="G_NME3" fbc:label="G_NME3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000103024</p> + <p>HGNC ID: HGNC:7851</p> + <p>HGNC symbol: NME3</p> + <p>entrez_id: 4832</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_NME7" fbc:name="G_NME7" fbc:label="G_NME7"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17109,26 +17117,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NME3" fbc:name="G_NME3" fbc:label="G_NME3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000103024</p> - <p>HGNC ID: HGNC:7851</p> - <p>HGNC symbol: NME3</p> - <p>entrez_id: 4832</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_NME2" fbc:name="G_NME2" fbc:label="G_NME2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000243678</p> - <p>HGNC ID: HGNC:7850</p> - <p>HGNC symbol: NME2</p> - <p>entrez_id: 4831</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_NME1" fbc:name="G_NME1" fbc:label="G_NME1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17149,13 +17137,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CTPS2" fbc:name="G_CTPS2" fbc:label="G_CTPS2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000047230</p> - <p>HGNC ID: HGNC:2520</p> - <p>HGNC symbol: CTPS2</p> - <p>entrez_id: 56474</p> + <fbc:geneProduct fbc:id="G_NME2" fbc:name="G_NME2" fbc:label="G_NME2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000243678</p> + <p>HGNC ID: HGNC:7850</p> + <p>HGNC symbol: NME2</p> + <p>entrez_id: 4831</p> </html> </notes> </fbc:geneProduct> @@ -17169,6 +17157,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CTPS2" fbc:name="G_CTPS2" fbc:label="G_CTPS2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000047230</p> + <p>HGNC ID: HGNC:2520</p> + <p>HGNC symbol: CTPS2</p> + <p>entrez_id: 56474</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GLUD2" fbc:name="G_GLUD2" fbc:label="G_GLUD2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17209,6 +17207,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC25A13" fbc:name="G_SLC25A13" fbc:label="G_SLC25A13"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000004864</p> + <p>HGNC ID: HGNC:10983</p> + <p>HGNC symbol: SLC25A13</p> + <p>entrez_id: 10165</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC25A12" fbc:name="G_SLC25A12" fbc:label="G_SLC25A12"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17219,16 +17227,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC25A13" fbc:name="G_SLC25A13" fbc:label="G_SLC25A13"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000004864</p> - <p>HGNC ID: HGNC:10983</p> - <p>HGNC symbol: SLC25A13</p> - <p>entrez_id: 10165</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_CPS1" fbc:name="G_CPS1" fbc:label="G_CPS1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17249,6 +17247,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC25A15" fbc:name="G_SLC25A15" fbc:label="G_SLC25A15"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000102743</p> + <p>HGNC ID: HGNC:10985</p> + <p>HGNC symbol: SLC25A15</p> + <p>entrez_id: 10166</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC25A2" fbc:name="G_SLC25A2" fbc:label="G_SLC25A2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17259,16 +17267,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC25A15" fbc:name="G_SLC25A15" fbc:label="G_SLC25A15"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000102743</p> - <p>HGNC ID: HGNC:10985</p> - <p>HGNC symbol: SLC25A15</p> - <p>entrez_id: 10166</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ASS1" fbc:name="G_ASS1" fbc:label="G_ASS1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17369,6 +17367,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_AQP5" fbc:name="G_AQP5" fbc:label="G_AQP5"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000161798</p> + <p>HGNC ID: HGNC:638</p> + <p>HGNC symbol: AQP5</p> + <p>entrez_id: 362</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_AQP4" fbc:name="G_AQP4" fbc:label="G_AQP4"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17379,6 +17387,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_AQP1" fbc:name="G_AQP1" fbc:label="G_AQP1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000240583</p> + <p>HGNC ID: HGNC:633</p> + <p>HGNC symbol: AQP1</p> + <p>entrez_id: 358</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_AQP2" fbc:name="G_AQP2" fbc:label="G_AQP2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17389,26 +17407,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_AQP1" fbc:name="G_AQP1" fbc:label="G_AQP1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000240583</p> - <p>HGNC ID: HGNC:633</p> - <p>HGNC symbol: AQP1</p> - <p>entrez_id: 358</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_AQP5" fbc:name="G_AQP5" fbc:label="G_AQP5"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000161798</p> - <p>HGNC ID: HGNC:638</p> - <p>HGNC symbol: AQP5</p> - <p>entrez_id: 362</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC22A1" fbc:name="G_SLC22A1" fbc:label="G_SLC22A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17579,6 +17577,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_FOLR1" fbc:name="G_FOLR1" fbc:label="G_FOLR1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000110195</p> + <p>HGNC ID: HGNC:3791</p> + <p>HGNC symbol: FOLR1</p> + <p>entrez_id: 2348</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_FOLR3" fbc:name="G_FOLR3" fbc:label="G_FOLR3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17589,16 +17597,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_FOLR1" fbc:name="G_FOLR1" fbc:label="G_FOLR1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000110195</p> - <p>HGNC ID: HGNC:3791</p> - <p>HGNC symbol: FOLR1</p> - <p>entrez_id: 2348</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_BCAT1" fbc:name="G_BCAT1" fbc:label="G_BCAT1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17689,6 +17687,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ACAD8" fbc:name="G_ACAD8" fbc:label="G_ACAD8"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000151498</p> + <p>HGNC ID: HGNC:87</p> + <p>HGNC symbol: ACAD8</p> + <p>entrez_id: 27034</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ACADM" fbc:name="G_ACADM" fbc:label="G_ACADM"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17699,13 +17707,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ACAD8" fbc:name="G_ACAD8" fbc:label="G_ACAD8"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000151498</p> - <p>HGNC ID: HGNC:87</p> - <p>HGNC symbol: ACAD8</p> - <p>entrez_id: 27034</p> + <fbc:geneProduct fbc:id="G_ECHS1" fbc:name="G_ECHS1" fbc:label="G_ECHS1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000127884</p> + <p>HGNC ID: HGNC:3151</p> + <p>HGNC symbol: ECHS1</p> + <p>entrez_id: 1892</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_HADHB" fbc:name="G_HADHB" fbc:label="G_HADHB"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000138029</p> + <p>HGNC ID: HGNC:4803</p> + <p>HGNC symbol: HADHB</p> + <p>entrez_id: 3032</p> </html> </notes> </fbc:geneProduct> @@ -17719,26 +17737,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_HADHB" fbc:name="G_HADHB" fbc:label="G_HADHB"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000138029</p> - <p>HGNC ID: HGNC:4803</p> - <p>HGNC symbol: HADHB</p> - <p>entrez_id: 3032</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ECHS1" fbc:name="G_ECHS1" fbc:label="G_ECHS1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000127884</p> - <p>HGNC ID: HGNC:3151</p> - <p>HGNC symbol: ECHS1</p> - <p>entrez_id: 1892</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_HIBADH" fbc:name="G_HIBADH" fbc:label="G_HIBADH"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17759,13 +17757,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ALDH3A2" fbc:name="G_ALDH3A2" fbc:label="G_ALDH3A2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000072210</p> - <p>HGNC ID: HGNC:403</p> - <p>HGNC symbol: ALDH3A2</p> - <p>entrez_id: 224</p> + <fbc:geneProduct fbc:id="G_ALDH1B1" fbc:name="G_ALDH1B1" fbc:label="G_ALDH1B1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000137124</p> + <p>HGNC ID: HGNC:407</p> + <p>HGNC symbol: ALDH1B1</p> + <p>entrez_id: 219</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ALDH7A1" fbc:name="G_ALDH7A1" fbc:label="G_ALDH7A1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000164904</p> + <p>HGNC ID: HGNC:877</p> + <p>HGNC symbol: ALDH7A1</p> + <p>entrez_id: 501</p> </html> </notes> </fbc:geneProduct> @@ -17779,23 +17787,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ALDH7A1" fbc:name="G_ALDH7A1" fbc:label="G_ALDH7A1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000164904</p> - <p>HGNC ID: HGNC:877</p> - <p>HGNC symbol: ALDH7A1</p> - <p>entrez_id: 501</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ALDH1B1" fbc:name="G_ALDH1B1" fbc:label="G_ALDH1B1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000137124</p> - <p>HGNC ID: HGNC:407</p> - <p>HGNC symbol: ALDH1B1</p> - <p>entrez_id: 219</p> + <fbc:geneProduct fbc:id="G_ALDH3A2" fbc:name="G_ALDH3A2" fbc:label="G_ALDH3A2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000072210</p> + <p>HGNC ID: HGNC:403</p> + <p>HGNC symbol: ALDH3A2</p> + <p>entrez_id: 224</p> </html> </notes> </fbc:geneProduct> @@ -17889,6 +17887,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GPT" fbc:name="G_GPT" fbc:label="G_GPT"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167701</p> + <p>HGNC ID: HGNC:4552</p> + <p>HGNC symbol: GPT</p> + <p>entrez_id: 2875</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GPT2" fbc:name="G_GPT2" fbc:label="G_GPT2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17899,16 +17907,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_GPT" fbc:name="G_GPT" fbc:label="G_GPT"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167701</p> - <p>HGNC ID: HGNC:4552</p> - <p>HGNC symbol: GPT</p> - <p>entrez_id: 2875</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SHMT2" fbc:name="G_SHMT2" fbc:label="G_SHMT2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17969,6 +17967,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ALDH1L1" fbc:name="G_ALDH1L1" fbc:label="G_ALDH1L1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000144908</p> + <p>HGNC ID: HGNC:3978</p> + <p>HGNC symbol: ALDH1L1</p> + <p>entrez_id: 10840</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ALDH1L2" fbc:name="G_ALDH1L2" fbc:label="G_ALDH1L2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -17979,16 +17987,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ALDH1L1" fbc:name="G_ALDH1L1" fbc:label="G_ALDH1L1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000144908</p> - <p>HGNC ID: HGNC:3978</p> - <p>HGNC symbol: ALDH1L1</p> - <p>entrez_id: 10840</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_MTHFD2L" fbc:name="G_MTHFD2L" fbc:label="G_MTHFD2L"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18049,6 +18047,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_IDI1" fbc:name="G_IDI1" fbc:label="G_IDI1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000067064</p> + <p>HGNC ID: HGNC:5387</p> + <p>HGNC symbol: IDI1</p> + <p>entrez_id: 3422</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_IDI2" fbc:name="G_IDI2" fbc:label="G_IDI2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18059,16 +18067,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_IDI1" fbc:name="G_IDI1" fbc:label="G_IDI1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000067064</p> - <p>HGNC ID: HGNC:5387</p> - <p>HGNC symbol: IDI1</p> - <p>entrez_id: 3422</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_MVD" fbc:name="G_MVD" fbc:label="G_MVD"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18149,6 +18147,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_MSMO1" fbc:name="G_MSMO1" fbc:label="G_MSMO1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000052802</p> + <p>HGNC ID: HGNC:10545</p> + <p>HGNC symbol: MSMO1</p> + <p>entrez_id: 6307</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_FAXDC2" fbc:name="G_FAXDC2" fbc:label="G_FAXDC2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18159,16 +18167,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_MSMO1" fbc:name="G_MSMO1" fbc:label="G_MSMO1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000052802</p> - <p>HGNC ID: HGNC:10545</p> - <p>HGNC symbol: MSMO1</p> - <p>entrez_id: 6307</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_NSDHL" fbc:name="G_NSDHL" fbc:label="G_NSDHL"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18269,16 +18267,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ACSL6" fbc:name="G_ACSL6" fbc:label="G_ACSL6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000164398</p> - <p>HGNC ID: HGNC:16496</p> - <p>HGNC symbol: ACSL6</p> - <p>entrez_id: 23305</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ACSL4" fbc:name="G_ACSL4" fbc:label="G_ACSL4"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18309,13 +18297,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CPT1B" fbc:name="G_CPT1B" fbc:label="G_CPT1B"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000205560</p> - <p>HGNC ID: HGNC:2329</p> - <p>HGNC symbol: CPT1B</p> - <p>entrez_id: 1375</p> + <fbc:geneProduct fbc:id="G_ACSL6" fbc:name="G_ACSL6" fbc:label="G_ACSL6"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000164398</p> + <p>HGNC ID: HGNC:16496</p> + <p>HGNC symbol: ACSL6</p> + <p>entrez_id: 23305</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CPT1C" fbc:name="G_CPT1C" fbc:label="G_CPT1C"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000169169</p> + <p>HGNC ID: HGNC:18540</p> + <p>HGNC symbol: CPT1C</p> + <p>entrez_id: 126129</p> </html> </notes> </fbc:geneProduct> @@ -18329,13 +18327,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CPT1C" fbc:name="G_CPT1C" fbc:label="G_CPT1C"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000169169</p> - <p>HGNC ID: HGNC:18540</p> - <p>HGNC symbol: CPT1C</p> - <p>entrez_id: 126129</p> + <fbc:geneProduct fbc:id="G_CPT1B" fbc:name="G_CPT1B" fbc:label="G_CPT1B"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000205560</p> + <p>HGNC ID: HGNC:2329</p> + <p>HGNC symbol: CPT1B</p> + <p>entrez_id: 1375</p> </html> </notes> </fbc:geneProduct> @@ -18359,13 +18357,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ACADVL" fbc:name="G_ACADVL" fbc:label="G_ACADVL"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000072778</p> - <p>HGNC ID: HGNC:92</p> - <p>HGNC symbol: ACADVL</p> - <p>entrez_id: 37</p> + <fbc:geneProduct fbc:id="G_ACAA2" fbc:name="G_ACAA2" fbc:label="G_ACAA2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167315</p> + <p>HGNC ID: HGNC:83</p> + <p>HGNC symbol: ACAA2</p> + <p>entrez_id: 10449</p> </html> </notes> </fbc:geneProduct> @@ -18379,23 +18377,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ACAA2" fbc:name="G_ACAA2" fbc:label="G_ACAA2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167315</p> - <p>HGNC ID: HGNC:83</p> - <p>HGNC symbol: ACAA2</p> - <p>entrez_id: 10449</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A9" fbc:name="G_SLC2A9" fbc:label="G_SLC2A9"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000109667</p> - <p>HGNC ID: HGNC:13446</p> - <p>HGNC symbol: SLC2A9</p> - <p>entrez_id: 56606</p> + <fbc:geneProduct fbc:id="G_ACADVL" fbc:name="G_ACADVL" fbc:label="G_ACADVL"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000072778</p> + <p>HGNC ID: HGNC:92</p> + <p>HGNC symbol: ACADVL</p> + <p>entrez_id: 37</p> </html> </notes> </fbc:geneProduct> @@ -18409,46 +18397,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A14" fbc:name="G_SLC2A14" fbc:label="G_SLC2A14"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000173262</p> - <p>HGNC ID: HGNC:18301</p> - <p>HGNC symbol: SLC2A14</p> - <p>entrez_id: 144195</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC5A7" fbc:name="G_SLC5A7" fbc:label="G_SLC5A7"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000115665</p> - <p>HGNC ID: HGNC:14025</p> - <p>HGNC symbol: SLC5A7</p> - <p>entrez_id: 60482</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC5A1" fbc:name="G_SLC5A1" fbc:label="G_SLC5A1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000100170</p> - <p>HGNC ID: HGNC:11036</p> - <p>HGNC symbol: SLC5A1</p> - <p>entrez_id: 6523</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A6" fbc:name="G_SLC2A6" fbc:label="G_SLC2A6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000160326</p> - <p>HGNC ID: HGNC:11011</p> - <p>HGNC symbol: SLC2A6</p> - <p>entrez_id: 11182</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC2A8" fbc:name="G_SLC2A8" fbc:label="G_SLC2A8"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18469,16 +18417,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A1" fbc:name="G_SLC2A1" fbc:label="G_SLC2A1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000117394</p> - <p>HGNC ID: HGNC:11005</p> - <p>HGNC symbol: SLC2A1</p> - <p>entrez_id: 6513</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC5A12" fbc:name="G_SLC5A12" fbc:label="G_SLC5A12"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18489,26 +18427,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC5A10" fbc:name="G_SLC5A10" fbc:label="G_SLC5A10"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000154025</p> - <p>HGNC ID: HGNC:23155</p> - <p>HGNC symbol: SLC5A10</p> - <p>entrez_id: 125206</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A4" fbc:name="G_SLC2A4" fbc:label="G_SLC2A4"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000181856</p> - <p>HGNC ID: HGNC:11009</p> - <p>HGNC symbol: SLC2A4</p> - <p>entrez_id: 6517</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC5A4" fbc:name="G_SLC5A4" fbc:label="G_SLC5A4"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18519,76 +18437,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A5" fbc:name="G_SLC2A5" fbc:label="G_SLC2A5"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000142583</p> - <p>HGNC ID: HGNC:11010</p> - <p>HGNC symbol: SLC2A5</p> - <p>entrez_id: 6518</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC5A3" fbc:name="G_SLC5A3" fbc:label="G_SLC5A3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000198743</p> - <p>HGNC ID: HGNC:11038</p> - <p>HGNC symbol: SLC5A3</p> - <p>entrez_id: 6526</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC5A9" fbc:name="G_SLC5A9" fbc:label="G_SLC5A9"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000117834</p> - <p>HGNC ID: HGNC:22146</p> - <p>HGNC symbol: SLC5A9</p> - <p>entrez_id: 200010</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC5A6" fbc:name="G_SLC5A6" fbc:label="G_SLC5A6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000138074</p> - <p>HGNC ID: HGNC:11041</p> - <p>HGNC symbol: SLC5A6</p> - <p>entrez_id: 8884</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A3" fbc:name="G_SLC2A3" fbc:label="G_SLC2A3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000059804</p> - <p>HGNC ID: HGNC:11007</p> - <p>HGNC symbol: SLC2A3</p> - <p>entrez_id: 6515</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A10" fbc:name="G_SLC2A10" fbc:label="G_SLC2A10"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000197496</p> - <p>HGNC ID: HGNC:13444</p> - <p>HGNC symbol: SLC2A10</p> - <p>entrez_id: 81031</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A11" fbc:name="G_SLC2A11" fbc:label="G_SLC2A11"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000133460</p> - <p>HGNC ID: HGNC:14239</p> - <p>HGNC symbol: SLC2A11</p> - <p>entrez_id: 66035</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC2A7" fbc:name="G_SLC2A7" fbc:label="G_SLC2A7"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18609,33 +18457,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A2" fbc:name="G_SLC2A2" fbc:label="G_SLC2A2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000163581</p> - <p>HGNC ID: HGNC:11006</p> - <p>HGNC symbol: SLC2A2</p> - <p>entrez_id: 6514</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC2A13" fbc:name="G_SLC2A13" fbc:label="G_SLC2A13"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000151229</p> - <p>HGNC ID: HGNC:15956</p> - <p>HGNC symbol: SLC2A13</p> - <p>entrez_id: 114134</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC5A2" fbc:name="G_SLC5A2" fbc:label="G_SLC5A2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000140675</p> - <p>HGNC ID: HGNC:11037</p> - <p>HGNC symbol: SLC5A2</p> - <p>entrez_id: 6524</p> + <fbc:geneProduct fbc:id="G_SLC5A1" fbc:name="G_SLC5A1" fbc:label="G_SLC5A1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000100170</p> + <p>HGNC ID: HGNC:11036</p> + <p>HGNC symbol: SLC5A1</p> + <p>entrez_id: 6523</p> </html> </notes> </fbc:geneProduct> @@ -18649,23 +18477,173 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC38A1" fbc:name="G_SLC38A1" fbc:label="G_SLC38A1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000111371</p> - <p>HGNC ID: HGNC:13447</p> - <p>HGNC symbol: SLC38A1</p> - <p>entrez_id: 81539</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC3A2" fbc:name="G_SLC3A2" 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<fbc:geneProduct fbc:id="G_SLC2A6" fbc:name="G_SLC2A6" fbc:label="G_SLC2A6"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000160326</p> + <p>HGNC ID: HGNC:11011</p> + <p>HGNC symbol: SLC2A6</p> + <p>entrez_id: 11182</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC2A13" fbc:name="G_SLC2A13" fbc:label="G_SLC2A13"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000151229</p> + <p>HGNC ID: HGNC:15956</p> + <p>HGNC symbol: SLC2A13</p> + <p>entrez_id: 114134</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC2A4" fbc:name="G_SLC2A4" fbc:label="G_SLC2A4"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000181856</p> + <p>HGNC ID: HGNC:11009</p> + <p>HGNC symbol: SLC2A4</p> + <p>entrez_id: 6517</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC2A11" fbc:name="G_SLC2A11" fbc:label="G_SLC2A11"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000133460</p> + <p>HGNC ID: HGNC:14239</p> + <p>HGNC symbol: SLC2A11</p> + <p>entrez_id: 66035</p> </html> </notes> </fbc:geneProduct> @@ -18679,33 +18657,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC38A4" fbc:name="G_SLC38A4" fbc:label="G_SLC38A4"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000139209</p> - <p>HGNC ID: HGNC:14679</p> - <p>HGNC symbol: SLC38A4</p> - <p>entrez_id: 55089</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC7A6" fbc:name="G_SLC7A6" fbc:label="G_SLC7A6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000103064</p> - <p>HGNC ID: HGNC:11064</p> - <p>HGNC symbol: SLC7A6</p> - <p>entrez_id: 9057</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC7A5" fbc:name="G_SLC7A5" fbc:label="G_SLC7A5"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000103257</p> - <p>HGNC ID: HGNC:11063</p> - <p>HGNC symbol: SLC7A5</p> - <p>entrez_id: 8140</p> + <fbc:geneProduct fbc:id="G_CLTRN" fbc:name="G_CLTRN" fbc:label="G_CLTRN"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000147003</p> + <p>HGNC ID: HGNC:29437</p> + <p>HGNC symbol: CLTRN</p> + <p>entrez_id: 57393</p> </html> </notes> </fbc:geneProduct> @@ -18719,26 +18677,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CLTRN" fbc:name="G_CLTRN" fbc:label="G_CLTRN"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000147003</p> - <p>HGNC ID: HGNC:29437</p> - <p>HGNC symbol: CLTRN</p> - <p>entrez_id: 57393</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_ACE2" fbc:name="G_ACE2" fbc:label="G_ACE2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000130234</p> - <p>HGNC ID: HGNC:13557</p> - <p>HGNC symbol: ACE2</p> - <p>entrez_id: 59272</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC7A10" fbc:name="G_SLC7A10" fbc:label="G_SLC7A10"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18749,6 +18687,46 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC7A6" fbc:name="G_SLC7A6" fbc:label="G_SLC7A6"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000103064</p> + <p>HGNC ID: HGNC:11064</p> + <p>HGNC symbol: SLC7A6</p> + <p>entrez_id: 9057</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC38A4" fbc:name="G_SLC38A4" fbc:label="G_SLC38A4"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000139209</p> + <p>HGNC ID: HGNC:14679</p> + <p>HGNC symbol: SLC38A4</p> + <p>entrez_id: 55089</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC3A2" fbc:name="G_SLC3A2" fbc:label="G_SLC3A2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000168003</p> + <p>HGNC ID: HGNC:11026</p> + <p>HGNC symbol: SLC3A2</p> + <p>entrez_id: 6520</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC38A1" fbc:name="G_SLC38A1" fbc:label="G_SLC38A1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000111371</p> + <p>HGNC ID: HGNC:13447</p> + <p>HGNC symbol: SLC38A1</p> + <p>entrez_id: 81539</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC43A1" fbc:name="G_SLC43A1" fbc:label="G_SLC43A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18759,13 +18737,23 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC6A19" fbc:name="G_SLC6A19" fbc:label="G_SLC6A19"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000174358</p> - <p>HGNC ID: HGNC:27960</p> - <p>HGNC symbol: SLC6A19</p> - <p>entrez_id: 340024</p> + <fbc:geneProduct fbc:id="G_SLC7A5" fbc:name="G_SLC7A5" fbc:label="G_SLC7A5"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000103257</p> + <p>HGNC ID: HGNC:11063</p> + <p>HGNC symbol: SLC7A5</p> + <p>entrez_id: 8140</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_ACE2" fbc:name="G_ACE2" fbc:label="G_ACE2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000130234</p> + <p>HGNC ID: HGNC:13557</p> + <p>HGNC symbol: ACE2</p> + <p>entrez_id: 59272</p> </html> </notes> </fbc:geneProduct> @@ -18779,13 +18767,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC6A14" fbc:name="G_SLC6A14" fbc:label="G_SLC6A14"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000268104</p> - <p>HGNC ID: HGNC:11047</p> - <p>HGNC symbol: SLC6A14</p> - <p>entrez_id: 11254</p> + <fbc:geneProduct fbc:id="G_SLC6A19" fbc:name="G_SLC6A19" fbc:label="G_SLC6A19"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000174358</p> + <p>HGNC ID: HGNC:27960</p> + <p>HGNC symbol: SLC6A19</p> + <p>entrez_id: 340024</p> </html> </notes> </fbc:geneProduct> @@ -18799,6 +18787,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC6A14" fbc:name="G_SLC6A14" fbc:label="G_SLC6A14"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000268104</p> + <p>HGNC ID: HGNC:11047</p> + <p>HGNC symbol: SLC6A14</p> + <p>entrez_id: 11254</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_FOLR2" fbc:name="G_FOLR2" fbc:label="G_FOLR2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18809,6 +18807,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC7A9" fbc:name="G_SLC7A9" fbc:label="G_SLC7A9"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000021488</p> + <p>HGNC ID: HGNC:11067</p> + <p>HGNC symbol: SLC7A9</p> + <p>entrez_id: 11136</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC7A3" fbc:name="G_SLC7A3" fbc:label="G_SLC7A3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18819,23 +18827,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC7A9" fbc:name="G_SLC7A9" fbc:label="G_SLC7A9"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000021488</p> - <p>HGNC ID: HGNC:11067</p> - <p>HGNC symbol: SLC7A9</p> - <p>entrez_id: 11136</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC7A2" fbc:name="G_SLC7A2" fbc:label="G_SLC7A2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000003989</p> - <p>HGNC ID: HGNC:11060</p> - <p>HGNC symbol: SLC7A2</p> - <p>entrez_id: 6542</p> + <fbc:geneProduct fbc:id="G_SLC7A7" fbc:name="G_SLC7A7" fbc:label="G_SLC7A7"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000155465</p> + <p>HGNC ID: HGNC:11065</p> + <p>HGNC symbol: SLC7A7</p> + <p>entrez_id: 9056</p> </html> </notes> </fbc:geneProduct> @@ -18849,13 +18847,33 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC7A7" fbc:name="G_SLC7A7" fbc:label="G_SLC7A7"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000155465</p> - <p>HGNC ID: HGNC:11065</p> - <p>HGNC symbol: SLC7A7</p> - <p>entrez_id: 9056</p> + <fbc:geneProduct fbc:id="G_SLC7A2" fbc:name="G_SLC7A2" fbc:label="G_SLC7A2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000003989</p> + <p>HGNC ID: HGNC:11060</p> + <p>HGNC symbol: SLC7A2</p> + <p>entrez_id: 6542</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC16A10" fbc:name="G_SLC16A10" fbc:label="G_SLC16A10"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000112394</p> + <p>HGNC ID: HGNC:17027</p> + <p>HGNC symbol: SLC16A10</p> + <p>entrez_id: 117247</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC43A2" fbc:name="G_SLC43A2" fbc:label="G_SLC43A2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000278550</p> + <p>HGNC ID: HGNC:23087</p> + <p>HGNC symbol: SLC43A2</p> + <p>entrez_id: 124935</p> </html> </notes> </fbc:geneProduct> @@ -18869,26 +18887,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC43A2" fbc:name="G_SLC43A2" fbc:label="G_SLC43A2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000278550</p> - <p>HGNC ID: HGNC:23087</p> - <p>HGNC symbol: SLC43A2</p> - <p>entrez_id: 124935</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC16A10" fbc:name="G_SLC16A10" fbc:label="G_SLC16A10"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000112394</p> - <p>HGNC ID: HGNC:17027</p> - <p>HGNC symbol: SLC16A10</p> - <p>entrez_id: 117247</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC22A5" fbc:name="G_SLC22A5" fbc:label="G_SLC22A5"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18909,16 +18907,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC6A5" fbc:name="G_SLC6A5" fbc:label="G_SLC6A5"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000165970</p> - <p>HGNC ID: HGNC:11051</p> - <p>HGNC symbol: SLC6A5</p> - <p>entrez_id: 9152</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC6A9" fbc:name="G_SLC6A9" fbc:label="G_SLC6A9"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -18939,13 +18927,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC6A20" fbc:name="G_SLC6A20" fbc:label="G_SLC6A20"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000163817</p> - <p>HGNC ID: HGNC:30927</p> - <p>HGNC symbol: SLC6A20</p> - <p>entrez_id: 54716</p> + <fbc:geneProduct fbc:id="G_SLC6A5" fbc:name="G_SLC6A5" fbc:label="G_SLC6A5"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000165970</p> + <p>HGNC ID: HGNC:11051</p> + <p>HGNC symbol: SLC6A5</p> + <p>entrez_id: 9152</p> </html> </notes> </fbc:geneProduct> @@ -18969,13 +18957,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CD36" fbc:name="G_CD36" fbc:label="G_CD36"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000135218</p> - <p>HGNC ID: HGNC:1663</p> - <p>HGNC symbol: CD36</p> - <p>entrez_id: 948</p> + <fbc:geneProduct fbc:id="G_SLC6A20" fbc:name="G_SLC6A20" fbc:label="G_SLC6A20"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000163817</p> + <p>HGNC ID: HGNC:30927</p> + <p>HGNC symbol: SLC6A20</p> + <p>entrez_id: 54716</p> </html> </notes> </fbc:geneProduct> @@ -18989,6 +18977,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CD36" fbc:name="G_CD36" fbc:label="G_CD36"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000135218</p> + <p>HGNC ID: HGNC:1663</p> + <p>HGNC symbol: CD36</p> + <p>entrez_id: 948</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC27A1" fbc:name="G_SLC27A1" fbc:label="G_SLC27A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19009,6 +19007,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC14A2" fbc:name="G_SLC14A2" fbc:label="G_SLC14A2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000132874</p> + <p>HGNC ID: HGNC:10919</p> + <p>HGNC symbol: SLC14A2</p> + <p>entrez_id: 8170</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC14A1" fbc:name="G_SLC14A1" fbc:label="G_SLC14A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19019,16 +19027,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC14A2" fbc:name="G_SLC14A2" fbc:label="G_SLC14A2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000132874</p> - <p>HGNC ID: HGNC:10919</p> - <p>HGNC symbol: SLC14A2</p> - <p>entrez_id: 8170</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC29A2" fbc:name="G_SLC29A2" fbc:label="G_SLC29A2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19049,13 +19047,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC1A2" fbc:name="G_SLC1A2" fbc:label="G_SLC1A2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000110436</p> - <p>HGNC ID: HGNC:10940</p> - <p>HGNC symbol: SLC1A2</p> - <p>entrez_id: 6506</p> + <fbc:geneProduct fbc:id="G_SLC1A7" fbc:name="G_SLC1A7" fbc:label="G_SLC1A7"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000162383</p> + <p>HGNC ID: HGNC:10945</p> + <p>HGNC symbol: SLC1A7</p> + <p>entrez_id: 6512</p> </html> </notes> </fbc:geneProduct> @@ -19069,6 +19067,36 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC1A2" fbc:name="G_SLC1A2" fbc:label="G_SLC1A2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000110436</p> + <p>HGNC ID: HGNC:10940</p> + <p>HGNC symbol: SLC1A2</p> + <p>entrez_id: 6506</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC1A6" fbc:name="G_SLC1A6" fbc:label="G_SLC1A6"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000105143</p> + <p>HGNC ID: HGNC:10944</p> + <p>HGNC symbol: SLC1A6</p> + <p>entrez_id: 6511</p> + </html> + </notes> + </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC1A3" fbc:name="G_SLC1A3" fbc:label="G_SLC1A3"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000079215</p> + <p>HGNC ID: HGNC:10941</p> + <p>HGNC symbol: SLC1A3</p> + <p>entrez_id: 6507</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC1A1" fbc:name="G_SLC1A1" fbc:label="G_SLC1A1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19079,36 +19107,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC1A3" fbc:name="G_SLC1A3" fbc:label="G_SLC1A3"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000079215</p> - <p>HGNC ID: HGNC:10941</p> - <p>HGNC symbol: SLC1A3</p> - <p>entrez_id: 6507</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC1A6" fbc:name="G_SLC1A6" fbc:label="G_SLC1A6"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000105143</p> - <p>HGNC ID: HGNC:10944</p> - <p>HGNC symbol: SLC1A6</p> - <p>entrez_id: 6511</p> - </html> - </notes> - </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC1A7" fbc:name="G_SLC1A7" fbc:label="G_SLC1A7"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000162383</p> - <p>HGNC ID: HGNC:10945</p> - <p>HGNC symbol: SLC1A7</p> - <p>entrez_id: 6512</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC1A4" fbc:name="G_SLC1A4" fbc:label="G_SLC1A4"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19129,6 +19127,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_CKM" fbc:name="G_CKM" fbc:label="G_CKM"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000104879</p> + <p>HGNC ID: HGNC:1994</p> + <p>HGNC symbol: CKM</p> + <p>entrez_id: 1158</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_CKB" fbc:name="G_CKB" fbc:label="G_CKB"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19139,13 +19147,13 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_CKM" fbc:name="G_CKM" fbc:label="G_CKM"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000104879</p> - <p>HGNC ID: HGNC:1994</p> - <p>HGNC symbol: CKM</p> - <p>entrez_id: 1158</p> + <fbc:geneProduct fbc:id="G_AOC2" fbc:name="G_AOC2" fbc:label="G_AOC2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000131480</p> + <p>HGNC ID: HGNC:549</p> + <p>HGNC symbol: AOC2</p> + <p>entrez_id: 314</p> </html> </notes> </fbc:geneProduct> @@ -19159,16 +19167,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_AOC2" fbc:name="G_AOC2" fbc:label="G_AOC2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000131480</p> - <p>HGNC ID: HGNC:549</p> - <p>HGNC symbol: AOC2</p> - <p>entrez_id: 314</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_AOC3" fbc:name="G_AOC3" fbc:label="G_AOC3"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19189,6 +19187,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_GAD1" fbc:name="G_GAD1" fbc:label="G_GAD1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000128683</p> + <p>HGNC ID: HGNC:4092</p> + <p>HGNC symbol: GAD1</p> + <p>entrez_id: 2571</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GAD2" fbc:name="G_GAD2" fbc:label="G_GAD2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19199,16 +19207,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_GAD1" fbc:name="G_GAD1" fbc:label="G_GAD1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000128683</p> - <p>HGNC ID: HGNC:4092</p> - <p>HGNC symbol: GAD1</p> - <p>entrez_id: 2571</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_HAL" fbc:name="G_HAL" fbc:label="G_HAL"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19389,6 +19387,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_IDO2" fbc:name="G_IDO2" fbc:label="G_IDO2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000188676</p> + <p>HGNC ID: HGNC:27269</p> + <p>HGNC symbol: IDO2</p> + <p>entrez_id: 169355</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_TDO2" fbc:name="G_TDO2" fbc:label="G_TDO2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19399,16 +19407,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_IDO2" fbc:name="G_IDO2" fbc:label="G_IDO2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000188676</p> - <p>HGNC ID: HGNC:27269</p> - <p>HGNC symbol: IDO2</p> - <p>entrez_id: 169355</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_IDO1" fbc:name="G_IDO1" fbc:label="G_IDO1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19479,6 +19477,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_TXNRD2" fbc:name="G_TXNRD2" fbc:label="G_TXNRD2"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000184470</p> + <p>HGNC ID: HGNC:18155</p> + <p>HGNC symbol: TXNRD2</p> + <p>entrez_id: 10587</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_TXNRD1" fbc:name="G_TXNRD1" fbc:label="G_TXNRD1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19489,16 +19497,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_TXNRD2" fbc:name="G_TXNRD2" fbc:label="G_TXNRD2"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000184470</p> - <p>HGNC ID: HGNC:18155</p> - <p>HGNC symbol: TXNRD2</p> - <p>entrez_id: 10587</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_ACAT1" fbc:name="G_ACAT1" fbc:label="G_ACAT1"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19519,6 +19517,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_TK1" fbc:name="G_TK1" fbc:label="G_TK1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000167900</p> + <p>HGNC ID: HGNC:11830</p> + <p>HGNC symbol: TK1</p> + <p>entrez_id: 7083</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_TK2" fbc:name="G_TK2" fbc:label="G_TK2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19529,16 +19537,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_TK1" fbc:name="G_TK1" fbc:label="G_TK1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000167900</p> - <p>HGNC ID: HGNC:11830</p> - <p>HGNC symbol: TK1</p> - <p>entrez_id: 7083</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC17A6" fbc:name="G_SLC17A6" fbc:label="G_SLC17A6"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19549,6 +19547,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_SLC17A8" fbc:name="G_SLC17A8" fbc:label="G_SLC17A8"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000179520</p> + <p>HGNC ID: HGNC:20151</p> + <p>HGNC symbol: SLC17A8</p> + <p>entrez_id: 246213</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_SLC17A7" fbc:name="G_SLC17A7" fbc:label="G_SLC17A7"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19559,16 +19567,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_SLC17A8" fbc:name="G_SLC17A8" fbc:label="G_SLC17A8"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000179520</p> - <p>HGNC ID: HGNC:20151</p> - <p>HGNC symbol: SLC17A8</p> - <p>entrez_id: 246213</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GALK2" fbc:name="G_GALK2" fbc:label="G_GALK2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19599,6 +19597,16 @@ </html> </notes> </fbc:geneProduct> + <fbc:geneProduct fbc:id="G_PGM1" fbc:name="G_PGM1" fbc:label="G_PGM1"> + <notes> + <html xmlns="http://www.w3.org/1999/xhtml"> + <p>ENSG: ENSG00000079739</p> + <p>HGNC ID: HGNC:8905</p> + <p>HGNC symbol: PGM1</p> + <p>entrez_id: 5236</p> + </html> + </notes> + </fbc:geneProduct> <fbc:geneProduct fbc:id="G_PGM2" fbc:name="G_PGM2" fbc:label="G_PGM2"> <notes> <html xmlns="http://www.w3.org/1999/xhtml"> @@ -19609,16 +19617,6 @@ </html> </notes> </fbc:geneProduct> - <fbc:geneProduct fbc:id="G_PGM1" fbc:name="G_PGM1" fbc:label="G_PGM1"> - <notes> - <html xmlns="http://www.w3.org/1999/xhtml"> - <p>ENSG: ENSG00000079739</p> - <p>HGNC ID: HGNC:8905</p> - <p>HGNC symbol: PGM1</p> - <p>entrez_id: 5236</p> - </html> - </notes> - </fbc:geneProduct> <fbc:geneProduct fbc:id="G_GALE" fbc:name="G_GALE" fbc:label="G_GALE"> <notes> <html xmlns="http://www.w3.org/1999/xhtml">
--- a/COBRAxy/metabolic_model_setting.py Mon Sep 29 10:33:26 2025 +0000 +++ b/COBRAxy/metabolic_model_setting.py Mon Sep 29 15:13:21 2025 +0000 @@ -16,6 +16,8 @@ from typing import Optional, Tuple, List import utils.model_utils as modelUtils import logging +from pathlib import Path + ARGS : argparse.Namespace def process_args(args: List[str] = None) -> argparse.Namespace: @@ -147,6 +149,24 @@ df.to_csv(path, sep="\t", index=False) except Exception as e: raise utils.DataErr(path, f"failed writing tabular output: {e}") + +def is_placeholder(gid) -> bool: + """Return True if the gene id looks like a placeholder (e.g., 0/NA/NAN/empty).""" + if gid is None: + return True + s = str(gid).strip().lower() + return s in {"0", "", "na", "nan"} # lowercase for simple matching + +def sample_valid_gene_ids(genes, limit=10): + """Yield up to `limit` valid gene IDs, skipping placeholders (e.g., the first 0 in RECON).""" + out = [] + for g in genes: + gid = getattr(g, "id", getattr(g, "gene_id", g)) + if not is_placeholder(gid): + out.append(str(gid)) + if len(out) >= limit: + break + return out ###############################- ENTRY POINT -################################ @@ -200,11 +220,14 @@ if value is not None: model.reactions.get_by_id(reaction).lower_bound = -float(value) + # Initialize translation_issues dictionary + translation_issues = {} + if (ARGS.name == "Recon" or ARGS.name == "ENGRO2") and ARGS.gene_format != "Default": logging.basicConfig(level=logging.INFO) logger = logging.getLogger(__name__) - model = modelUtils.translate_model_genes( + model, translation_issues = modelUtils.translate_model_genes( model=model, mapping_df= pd.read_csv(ARGS.tool_dir + "/local/mappings/genes_human.csv", dtype={'entrez_id': str}), target_nomenclature=ARGS.gene_format, @@ -212,6 +235,80 @@ logger=logger ) + if ARGS.name == "Custom_model" and ARGS.gene_format != "Default": + logging.basicConfig(level=logging.INFO) + logger = logging.getLogger(__name__) + + tmp_check = [] + for g in model.genes[1:5]: # check first 3 genes only + tmp_check.append(modelUtils.gene_type(g.id, "Custom_model")) + + if len(set(tmp_check)) > 1: + raise utils.DataErr("Custom_model", "The custom model contains genes with mixed or unrecognized nomenclature. Please ensure all genes use the same recognized nomenclature before applying gene_format conversion.") + else: + source_nomenclature = tmp_check[0] + + if source_nomenclature != ARGS.gene_format: + model, translation_issues = modelUtils.translate_model_genes( + model=model, + mapping_df= pd.read_csv(ARGS.tool_dir + "/local/mappings/genes_human.csv", dtype={'entrez_id': str}), + target_nomenclature=ARGS.gene_format, + source_nomenclature=source_nomenclature, + logger=logger + ) + + + + + if ARGS.name == "Custom_model" and ARGS.gene_format != "Default": + logger = logging.getLogger(__name__) + + # Take a small, clean sample of gene IDs (skipping placeholders like 0) + ids_sample = sample_valid_gene_ids(model.genes, limit=10) + if not ids_sample: + raise utils.DataErr( + "Custom_model", + "No valid gene IDs found (many may be placeholders like 0)." + ) + + # Detect source nomenclature on the sample + types = [] + for gid in ids_sample: + try: + t = modelUtils.gene_type(gid, "Custom_model") + except Exception as e: + # Keep it simple: skip problematic IDs + logger.debug(f"gene_type failed for {gid}: {e}") + t = None + if t: + types.append(t) + + if not types: + raise utils.DataErr( + "Custom_model", + "Could not detect a known gene nomenclature from the sample." + ) + + unique_types = set(types) + if len(unique_types) > 1: + raise utils.DataErr( + "Custom_model", + "Mixed or inconsistent gene nomenclatures detected. " + "Please unify them before converting." + ) + + source_nomenclature = types[0] + + # Convert only if needed + if source_nomenclature != ARGS.gene_format: + model, translation_issues = modelUtils.translate_model_genes( + model=model, + mapping_df= pd.read_csv(ARGS.tool_dir + "/local/mappings/genes_human.csv", dtype={'entrez_id': str}), + target_nomenclature=ARGS.gene_format, + source_nomenclature=source_nomenclature, + logger=logger + ) + # generate data rules = modelUtils.generate_rules(model, asParsed = False) reactions = modelUtils.generate_reactions(model, asParsed = False) @@ -225,6 +322,12 @@ df_rules = pd.DataFrame(list(rules.items()), columns = ["ReactionID", "GPR"]) df_reactions = pd.DataFrame(list(reactions.items()), columns = ["ReactionID", "Formula"]) + # Create DataFrame for translation issues + df_translation_issues = pd.DataFrame([ + {"ReactionID": rxn_id, "TranslationIssues": issues} + for rxn_id, issues in translation_issues.items() + ]) + df_bounds = bounds.reset_index().rename(columns = {"index": "ReactionID"}) df_medium = medium.rename(columns = {"reaction": "ReactionID"}) df_medium["InMedium"] = True @@ -235,6 +338,15 @@ if ARGS.name == "ENGRO2": merged = merged.merge(compartments, on = "ReactionID", how = "outer") merged = merged.merge(df_medium, on = "ReactionID", how = "left") + + # Add translation issues column + if not df_translation_issues.empty: + merged = merged.merge(df_translation_issues, on = "ReactionID", how = "left") + merged["TranslationIssues"] = merged["TranslationIssues"].fillna("") + else: + # Add empty TranslationIssues column if no issues found + #merged["TranslationIssues"] = "" + pass merged["InMedium"] = merged["InMedium"].fillna(False)
--- a/COBRAxy/metabolic_model_setting.xml Mon Sep 29 10:33:26 2025 +0000 +++ b/COBRAxy/metabolic_model_setting.xml Mon Sep 29 15:13:21 2025 +0000 @@ -81,6 +81,10 @@ </conditional> <param name="gene_format" argument="--gene_format" type="select" label="Gene nomenclature format:"> <option value="Default" selected="true">Keep original gene nomenclature</option> + <option value="HGNC_symbol">HGNC Symbol</option> + <option value="ENSG">ENSNG (Ensembl Gene ID)</option> + <option value="HGNC_ID">HGNC ID</option> + <option value="entrez_id">Entrez Gene ID</option> </param> </when> </conditional>
--- a/COBRAxy/ras_generator.py Mon Sep 29 10:33:26 2025 +0000 +++ b/COBRAxy/ras_generator.py Mon Sep 29 15:13:21 2025 +0000 @@ -106,97 +106,6 @@ rules.append(value) return (ids, rules) -############################ check_methods #################################### -def gene_type(l :str, name :str) -> str: - """ - Determine the type of gene ID. - - Args: - l (str): The gene identifier to check. - name (str): The name of the dataset, used in error messages. - - Returns: - str: The type of gene ID ('hugo_id', 'ensembl_gene_id', 'symbol', or 'entrez_id'). - - Raises: - sys.exit: If the gene ID type is not supported, the execution is aborted. - """ - if check_hgnc(l): - return 'hugo_id' - elif check_ensembl(l): - return 'ensembl_gene_id' - elif check_symbol(l): - return 'symbol' - elif check_entrez(l): - return 'entrez_id' - else: - sys.exit('Execution aborted:\n' + - 'gene ID type in ' + name + ' not supported. Supported ID'+ - 'types are: HUGO ID, Ensemble ID, HUGO symbol, Entrez ID\n') - -def check_hgnc(l :str) -> bool: - """ - Check if a gene identifier follows the HGNC format. - - Args: - l (str): The gene identifier to check. - - Returns: - bool: True if the gene identifier follows the HGNC format, False otherwise. - """ - if len(l) > 5: - if (l.upper()).startswith('HGNC:'): - return l[5:].isdigit() - else: - return False - else: - return False - -def check_ensembl(l :str) -> bool: - """ - Check if a gene identifier follows the Ensembl format. - - Args: - l (str): The gene identifier to check. - - Returns: - bool: True if the gene identifier follows the Ensembl format, False otherwise. - """ - return l.upper().startswith('ENS') - - -def check_symbol(l :str) -> bool: - """ - Check if a gene identifier follows the symbol format. - - Args: - l (str): The gene identifier to check. - - Returns: - bool: True if the gene identifier follows the symbol format, False otherwise. - """ - if len(l) > 0: - if l[0].isalpha() and l[1:].isalnum(): - return True - else: - return False - else: - return False - -def check_entrez(l :str) -> bool: - """ - Check if a gene identifier follows the Entrez ID format. - - Args: - l (str): The gene identifier to check. - - Returns: - bool: True if the gene identifier follows the Entrez ID format, False otherwise. - """ - if len(l) > 0: - return l.isdigit() - else: - return False ############################ gene ############################################# def data_gene(gene: pd.DataFrame, type_gene: str, name: str, gene_custom: Optional[Dict[str, str]]) -> Dict[str, str]:
--- a/COBRAxy/utils/model_utils.py Mon Sep 29 10:33:26 2025 +0000 +++ b/COBRAxy/utils/model_utils.py Mon Sep 29 15:13:21 2025 +0000 @@ -18,6 +18,100 @@ import utils.rule_parsing as rulesUtils import utils.reaction_parsing as reactionUtils from cobra import Model as cobraModel, Reaction, Metabolite +import sys + + +############################ check_methods #################################### +def gene_type(l :str, name :str) -> str: + """ + Determine the type of gene ID. + + Args: + l (str): The gene identifier to check. + name (str): The name of the dataset, used in error messages. + + Returns: + str: The type of gene ID ('hugo_id', 'ensembl_gene_id', 'symbol', or 'entrez_id'). + + Raises: + sys.exit: If the gene ID type is not supported, the execution is aborted. + """ + if check_hgnc(l): + return 'hugo_id' + elif check_ensembl(l): + return 'ensembl_gene_id' + elif check_symbol(l): + return 'symbol' + elif check_entrez(l): + return 'entrez_id' + else: + sys.exit('Execution aborted:\n' + + 'gene ID type in ' + name + ' not supported. Supported ID'+ + 'types are: HUGO ID, Ensemble ID, HUGO symbol, Entrez ID\n') + +def check_hgnc(l :str) -> bool: + """ + Check if a gene identifier follows the HGNC format. + + Args: + l (str): The gene identifier to check. + + Returns: + bool: True if the gene identifier follows the HGNC format, False otherwise. + """ + if len(l) > 5: + if (l.upper()).startswith('HGNC:'): + return l[5:].isdigit() + else: + return False + else: + return False + +def check_ensembl(l :str) -> bool: + """ + Check if a gene identifier follows the Ensembl format. + + Args: + l (str): The gene identifier to check. + + Returns: + bool: True if the gene identifier follows the Ensembl format, False otherwise. + """ + return l.upper().startswith('ENS') + + +def check_symbol(l :str) -> bool: + """ + Check if a gene identifier follows the symbol format. + + Args: + l (str): The gene identifier to check. + + Returns: + bool: True if the gene identifier follows the symbol format, False otherwise. + """ + if len(l) > 0: + if l[0].isalpha() and l[1:].isalnum(): + return True + else: + return False + else: + return False + +def check_entrez(l :str) -> bool: + """ + Check if a gene identifier follows the Entrez ID format. + + Args: + l (str): The gene identifier to check. + + Returns: + bool: True if the gene identifier follows the Entrez ID format, False otherwise. + """ + if len(l) > 0: + return l.isdigit() + else: + return False ################################- DATA GENERATION -################################ ReactionId = str @@ -506,110 +600,96 @@ def _simplify_boolean_expression(expr: str) -> str: """ - Simplify a boolean expression by removing duplicates and redundancies. - Handles expressions with 'and' and 'or'. + Simplify a boolean expression by removing duplicates while strictly preserving semantics. + This function handles simple duplicates within parentheses while being conservative about + complex expressions that could change semantics. """ if not expr or not expr.strip(): return expr - # normalize operators + # Normalize operators and whitespace expr = expr.replace(' AND ', ' and ').replace(' OR ', ' or ') + expr = ' '.join(expr.split()) # Normalize whitespace - # recursive helper to process expressions - def process_expression(s: str) -> str: - s = s.strip() - if not s: - return s - - # handle parentheses - while '(' in s: - # find the innermost parentheses - start = -1 - for i, c in enumerate(s): - if c == '(': - start = i - elif c == ')' and start != -1: - # process inner content - inner = s[start+1:i] - processed_inner = process_expression(inner) - s = s[:start] + processed_inner + s[i+1:] - break - else: - break - - # split by 'or' at top level - or_parts = [] - current_part = "" - paren_count = 0 - - tokens = s.split() - i = 0 - while i < len(tokens): - token = tokens[i] - if token == 'or' and paren_count == 0: - if current_part.strip(): - or_parts.append(current_part.strip()) - current_part = "" - else: - if token.count('(') > token.count(')'): - paren_count += token.count('(') - token.count(')') - elif token.count(')') > token.count('('): - paren_count -= token.count(')') - token.count('(') - current_part += token + " " - i += 1 + def simplify_parentheses_content(match_obj): + """Helper function to simplify content within parentheses.""" + content = match_obj.group(1) # Content inside parentheses - if current_part.strip(): - or_parts.append(current_part.strip()) - - # process each OR part - processed_or_parts = [] - for or_part in or_parts: - # split by 'and' within each OR part - and_parts = [] - current_and = "" - paren_count = 0 + # Only simplify if it's a pure OR or pure AND chain + if ' or ' in content and ' and ' not in content: + # Pure OR chain - safe to deduplicate + parts = [p.strip() for p in content.split(' or ') if p.strip()] + unique_parts = [] + seen = set() + for part in parts: + if part not in seen: + unique_parts.append(part) + seen.add(part) - and_tokens = or_part.split() - j = 0 - while j < len(and_tokens): - token = and_tokens[j] - if token == 'and' and paren_count == 0: - if current_and.strip(): - and_parts.append(current_and.strip()) - current_and = "" - else: - if token.count('(') > token.count(')'): - paren_count += token.count('(') - token.count(')') - elif token.count(')') > token.count('('): - paren_count -= token.count(')') - token.count('(') - current_and += token + " " - j += 1 + if len(unique_parts) == 1: + return unique_parts[0] # Remove unnecessary parentheses for single items + else: + return '(' + ' or '.join(unique_parts) + ')' + + elif ' and ' in content and ' or ' not in content: + # Pure AND chain - safe to deduplicate + parts = [p.strip() for p in content.split(' and ') if p.strip()] + unique_parts = [] + seen = set() + for part in parts: + if part not in seen: + unique_parts.append(part) + seen.add(part) - if current_and.strip(): - and_parts.append(current_and.strip()) - - # deduplicate AND parts - unique_and_parts = list(dict.fromkeys(and_parts)) # mantiene l'ordine - - if len(unique_and_parts) == 1: - processed_or_parts.append(unique_and_parts[0]) - elif len(unique_and_parts) > 1: - processed_or_parts.append(" and ".join(unique_and_parts)) + if len(unique_parts) == 1: + return unique_parts[0] # Remove unnecessary parentheses for single items + else: + return '(' + ' and '.join(unique_parts) + ')' + else: + # Mixed operators or single item - return with parentheses as-is + return '(' + content + ')' + + def remove_duplicates_simple(parts_str: str, separator: str) -> str: + """Remove duplicates from a simple chain of operations.""" + parts = [p.strip() for p in parts_str.split(separator) if p.strip()] - # deduplicate OR parts - unique_or_parts = list(dict.fromkeys(processed_or_parts)) + # Remove duplicates while preserving order + unique_parts = [] + seen = set() + for part in parts: + if part not in seen: + unique_parts.append(part) + seen.add(part) - if len(unique_or_parts) == 1: - return unique_or_parts[0] - elif len(unique_or_parts) > 1: - return " or ".join(unique_or_parts) + if len(unique_parts) == 1: + return unique_parts[0] else: - return "" + return f' {separator} '.join(unique_parts) try: - return process_expression(expr) + import re + + # First, simplify content within parentheses + # This handles cases like (A or A) -> A and (B and B) -> B + expr_simplified = re.sub(r'\(([^()]+)\)', simplify_parentheses_content, expr) + + # Check if the resulting expression has mixed operators + has_and = ' and ' in expr_simplified + has_or = ' or ' in expr_simplified + + # Only simplify top-level if it's pure AND or pure OR + if has_and and not has_or and '(' not in expr_simplified: + # Pure AND chain at top level - safe to deduplicate + return remove_duplicates_simple(expr_simplified, 'and') + elif has_or and not has_and and '(' not in expr_simplified: + # Pure OR chain at top level - safe to deduplicate + return remove_duplicates_simple(expr_simplified, 'or') + else: + # Mixed operators or has parentheses - return the simplified version (with parentheses content cleaned) + return expr_simplified + except Exception: - # if simplification fails, return the original expression + # If anything goes wrong, return the original expression return expr # ---------- Main public function ---------- @@ -618,7 +698,7 @@ target_nomenclature: str, source_nomenclature: str = 'hgnc_id', allow_many_to_one: bool = False, - logger: Optional[logging.Logger] = None) -> 'cobra.Model': + logger: Optional[logging.Logger] = None) -> Tuple['cobra.Model', Dict[str, str]]: """ Translate model genes from source_nomenclature to target_nomenclature using a mapping table. mapping_df should contain columns enabling mapping (e.g., ensg, hgnc_id, hgnc_symbol, entrez). @@ -630,6 +710,11 @@ source_nomenclature: Current source key in the model (default 'hgnc_id'). allow_many_to_one: If True, allow many-to-one mappings and handle duplicates in GPRs. logger: Optional logger. + + Returns: + Tuple containing: + - Translated COBRA model + - Dictionary mapping reaction IDs to translation issue descriptions """ if logger is None: logging.basicConfig(level=logging.INFO, format='%(asctime)s - %(levelname)s - %(message)s') @@ -701,6 +786,9 @@ stats = {'translated': 0, 'one_to_one': 0, 'one_to_many': 0, 'not_found': 0, 'simplified_gprs': 0} unmapped = [] multi = [] + + # Dictionary to store translation issues per reaction + reaction_translation_issues = {} original_genes = {g.id for g in model_copy.genes} logger.info(f"Original genes count: {len(original_genes)}") @@ -709,7 +797,10 @@ for rxn in model_copy.reactions: gpr = rxn.gene_reaction_rule if gpr and gpr.strip(): - new_gpr = _translate_gpr(gpr, gene_mapping, stats, unmapped, multi, logger) + new_gpr, rxn_issues = _translate_gpr(gpr, gene_mapping, stats, unmapped, multi, logger, track_issues=True) + if rxn_issues: + reaction_translation_issues[rxn.id] = rxn_issues + if new_gpr != gpr: simplified_gpr = _simplify_boolean_expression(new_gpr) if simplified_gpr != new_gpr: @@ -725,7 +816,7 @@ _log_translation_statistics(stats, unmapped, multi, original_genes, model_copy.genes, logger) logger.info("Translation finished") - return model_copy + return model_copy, reaction_translation_issues # ---------- helper functions ---------- @@ -762,10 +853,11 @@ stats: Dict[str, int], unmapped_genes: List[str], multi_mapping_genes: List[Tuple[str, List[str]]], - logger: logging.Logger) -> str: + logger: logging.Logger, + track_issues: bool = False) -> Union[str, Tuple[str, str]]: """ Translate genes inside a GPR string using gene_mapping. - Returns new GPR string. + Returns new GPR string, and optionally translation issues if track_issues=True. """ # Generic token pattern: letters, digits, :, _, -, ., (captures HGNC:1234, ENSG000..., symbols) token_pattern = r'\b[A-Za-z0-9:_.-]+\b' @@ -775,6 +867,7 @@ tokens = [t for t in tokens if t not in logical] new_gpr = gpr_string + issues = [] for token in sorted(set(tokens), key=lambda x: -len(x)): # longer tokens first to avoid partial replacement norm = _normalize_gene_id(token) @@ -788,6 +881,8 @@ stats['one_to_many'] += 1 multi_mapping_genes.append((token, targets)) replacement = "(" + " or ".join(targets) + ")" + if track_issues: + issues.append(f"{token} -> {' or '.join(targets)}") pattern = r'\b' + re.escape(token) + r'\b' new_gpr = re.sub(pattern, replacement, new_gpr) @@ -797,7 +892,32 @@ unmapped_genes.append(token) logger.debug(f"Token not found in mapping (left as-is): {token}") - return new_gpr + # Check for many-to-one cases (multiple source genes mapping to same target) + if track_issues: + # Build reverse mapping to detect many-to-one cases from original tokens + original_to_target = {} + + for orig_token in tokens: + norm = _normalize_gene_id(orig_token) + if norm in gene_mapping: + targets = gene_mapping[norm] + for target in targets: + if target not in original_to_target: + original_to_target[target] = [] + if orig_token not in original_to_target[target]: + original_to_target[target].append(orig_token) + + # Identify many-to-one mappings in this specific GPR + for target, original_genes in original_to_target.items(): + if len(original_genes) > 1: + issues.append(f"{' or '.join(original_genes)} -> {target}") + + issue_text = "; ".join(issues) if issues else "" + + if track_issues: + return new_gpr, issue_text + else: + return new_gpr def _update_model_genes(model: 'cobra.Model', logger: logging.Logger): @@ -874,4 +994,6 @@ if multi_mapping_genes: logger.info(f"Multi-mapping examples ({len(multi_mapping_genes)}):") for orig, targets in multi_mapping_genes[:10]: - logger.info(f" {orig} -> {', '.join(targets)}") \ No newline at end of file + logger.info(f" {orig} -> {', '.join(targets)}") + + \ No newline at end of file