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comparison Marea/local/HMRcoreMap.svg @ 0:23ac9cf12788 draft

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author bimib
date Tue, 06 Nov 2018 03:16:21 -0500
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377 y="1501.3895">= Fold change under threshold</text>
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383 y="1499.9501">Thickness is proportional to fold change</text>
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443 y="614.97485">Pyr</text>
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866 x="1001.889"
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901 class="st17 st18"
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903 y="242.86446">O</text>
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920 x="1268.7963"
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927 y="295.81955">ATP</text>
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933 y="295.39575">ADP</text>
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939 y="538.1087">ATP</text>
940 <text
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945 y="501.60864">ADP</text>
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951 y="538.3645">CoA</text>
952 <text
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957 y="522.77277">AcCoA</text>
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1457 class="st15 st16"
1458 x="1402.0922"
1459 y="899.6507">NH</text>
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1463 class="st15 st40"
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1489 class="st15 st16"
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1491 y="877.27655">AKG</text>
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1495 class="st15 st16"
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1500 d="m 275.8,872.81855 -60.2,-0.3 m 44.6,0.3 c 5.9,-1.5 4.4,-13.9 4.4,-13.9 m -26.7,14.1 c -6.2,-6.3 -6.2,-9.5 -6.8,-12.7"
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1506 class="st15 st38"
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1508 y="851.62427">Pi</text>
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1526 <text
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1544 <text
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1552 id="text393"
1553 class="st17 st18"
1554 x="647.54321"
1555 y="718.54126">NADPH</text>
1556 <text
1557 style="font-size:10px;font-family:Calibri"
1558 id="text395"
1559 class="st17 st18"
1560 x="620.67413"
1561 y="781.10181">NAD</text>
1562 <text
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1564 id="text397"
1565 class="st17 st18"
1566 x="649.48175"
1567 y="783.26978">NADH</text>
1568 <text
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1571 class="st15 st16"
1572 x="762.93884"
1573 y="808.12225">SuCoA</text>
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1577 class="st15 st16"
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1579 y="883.388">Succ</text>
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1583 class="st15 st16"
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1617 d="m 750,753.21855 c 11.4,9.5 20.7,21.6 27.4,35.6 m 7.1,-13.7 c -5.5,3.4 -13.1,1.9 -17.3,-3.3 -4.2,-5.2 -3.5,-12.4 1.5,-16.3"
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1625 x="770.49744"
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1630 class="st17 st18"
1631 x="788.89093"
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1633 <text
1634 style="font-size:10px;font-family:Calibri"
1635 id="text416"
1636 class="st17 st18"
1637 x="793.8714"
1638 y="758.63306">CoA</text>
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1641 d="m 804.5,854.61855 c -5.7,0.4 -11.1,-2.1 -14.1,-6.4 -3,-4.3 -3,-9.8 -0.1,-14.1 2.9,-4.3 8.3,-6.9 14,-6.5 m -18.4,38.9 c 3.7,-17.5 3.4,-35.7 -0.7,-53.3"
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1648 x="812.39685"
1649 y="828.55005">GDP</text>
1650 <text
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1652 id="text421"
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1656 <text
1657 style="font-size:10px;font-family:Calibri"
1658 id="text423"
1659 class="st17 st18"
1660 x="835.00421"
1661 y="828.55005">Pi</text>
1662 <text
1663 style="font-size:10px;font-family:Calibri"
1664 id="text425"
1665 class="st17 st18"
1666 x="814.06671"
1667 y="857.71606">GTP</text>
1668 <text
1669 style="font-size:10px;font-family:Calibri"
1670 id="text427"
1671 class="st17 st18"
1672 x="830.36554"
1673 y="857.71606">+</text>
1674 <text
1675 style="font-size:10px;font-family:Calibri"
1676 id="text429"
1677 class="st17 st18"
1678 x="835.34601"
1679 y="857.71606">CoA</text>
1680 <path
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1682 d="m 762.8,933.01855 c -4.7,-2.1 -7.7,-6.5 -7.5,-11.2 0.2,-4.7 3.4,-8.9 8.2,-10.5 4.8,-1.7 10.3,-0.5 14,2.9 m -2.6,-22 c -9,15.5 -21.4,28.8 -36.4,39.2"
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1686 style="font-size:10px;font-family:Calibri"
1687 id="text432"
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1689 x="784.63501"
1690 y="920.19165">FAD</text>
1691 <text
1692 style="font-size:10px;font-family:Calibri"
1693 id="text434"
1694 class="st17 st18"
1695 x="764.34894"
1696 y="943.30975">FADH</text>
1697 <text
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1699 id="text436"
1700 class="st17 st26"
1701 x="786.55115"
1702 y="945.30975">2</text>
1703 <path
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1712 x="537.08234"
1713 y="912.11646">NAD</text>
1714 <text
1715 style="font-size:16px;font-family:Calibri-Bold"
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1717 class="st15 st16"
1718 x="451.4158"
1719 y="732.70825">Pyr</text>
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1722 d="m 464.2,739.41855 0.2,56.6 m -0.5,-21.6 c 1.5,5.9 13.6,4.1 13.6,4.1 m -13.3,-14.1 c 1.5,5.9 13.4,4.1 13.4,4.1 m -13.1,1.8 c -1.6,-6 -12.9,-5.2 -12.9,-5.2 m 12.4,-12.6 c -1.5,-6 -12.4,-5.2 -12.4,-5.2 m 12.7,6.1 c 1.5,5.9 13.2,4.1 13.2,4.1"
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1727 style="font-size:10px;font-family:Calibri"
1728 id="text444"
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1730 x="567.64972"
1731 y="846.81366">H</text>
1732 <text
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1735 class="st17 st26"
1736 x="573.88025"
1737 y="848.81366">2</text>
1738 <text
1739 style="font-size:10px;font-family:Calibri"
1740 id="text448"
1741 class="st17 st18"
1742 x="576.96814"
1743 y="846.81366">O</text>
1744 <text
1745 style="font-size:10px;font-family:Calibri"
1746 id="text450"
1747 class="st17 st18"
1748 x="569.51593"
1749 y="825.74438">CoA</text>
1750 <text
1751 style="font-size:10px;font-family:Calibri"
1752 id="text452"
1753 class="st17 st18"
1754 x="695.72681"
1755 y="780.76196">CO</text>
1756 <text
1757 style="font-size:6.09369993px;font-family:Calibri"
1758 id="text454"
1759 class="st17 st26"
1760 x="707.5921"
1761 y="782.76196">2</text>
1762 <text
1763 style="font-size:10px;font-family:Calibri"
1764 id="text456"
1765 class="st17 st18"
1766 x="696.48865"
1767 y="719.4046">CO</text>
1768 <text
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1770 id="text458"
1771 class="st17 st26"
1772 x="708.35382"
1773 y="721.4046">2</text>
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1789 y="961.96796">H</text>
1790 <text
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1793 class="st17 st26"
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1799 class="st17 st18"
1800 x="681.7796"
1801 y="961.96796">O</text>
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1824 d="m 788.1,817.61855 c -3.6,-5.1 -3.6,-5.1 -3.6,-5.1 l 0.2,6.2 1.2,-2 2.2,0.9 z m 14.8,11.6 c 6,-1.6 6,-1.6 6,-1.6 l -5.9,-1.9 1.5,1.8 -1.6,1.7 z"
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1832 y="802.27655">Fum</text>
1833 <text
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1836 class="st15 st16"
1837 x="283.87378"
1838 y="800.91235">Fum</text>
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1859 class="st15 st38"
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1861 y="777.0979">Pi</text>
1862 <text
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1865 class="st15 st38"
1866 x="222.5813"
1867 y="777.03638">Pi</text>
1868 <text
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1870 id="text484"
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1872 x="482.52859"
1873 y="702.16626">H</text>
1874 <text
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1877 class="st17 st18"
1878 x="444.9617"
1879 y="668.1311">H</text>
1880 <text
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1883 class="st15 st16"
1884 x="465.6225"
1885 y="1131.1801">NAD</text>
1886 <text
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1889 class="st15 st16"
1890 x="499.44772"
1891 y="1131.5101">QH</text>
1892 <text
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1895 class="st15 st40"
1896 x="520.51807"
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1898 <text
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4953 style="font-size:10px;font-family:Calibri"
4954 id="text1328"
4955 class="st17 st18"
4956 x="928.5589"
4957 y="209.07054">4 Pi</text>
4958 <path
4959 style="fill:none;stroke:#000000;stroke-width:2.00309992"
4960 d="m 628.9,518.91855 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m -6.4,-11.7 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 12.1,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 14.1,11.6 -72.4,-0.2 m 19.7,-0.3 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.3,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
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4965 style="font-size:10px;font-family:Calibri"
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4967 class="st17 st18"
4968 x="619.48761"
4969 y="501.60864">Pi</text>
4970 <text
4971 style="font-size:10px;font-family:Calibri"
4972 id="text1333"
4973 class="st17 st18"
4974 x="925.4632"
4975 y="502.06665">CoA</text>
4976 <text
4977 style="font-size:10px;font-family:Calibri"
4978 id="text1335"
4979 class="st17 st18"
4980 x="978.2464"
4981 y="502.37036">3ADP</text>
4982 <text
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4985 class="st17 st18"
4986 x="944.37335"
4987 y="502.11053">2 NADP</text>
4988 <text
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4990 id="text1339"
4991 class="st17 st18"
4992 x="1005.5902"
4993 y="502.01004">Pi</text>
4994 <text
4995 style="font-size:10px;font-family:Calibri"
4996 id="text1341"
4997 class="st17 st18"
4998 x="1022.222"
4999 y="502.37036">CO2</text>
5000 <text
5001 style="font-size:10px;font-family:Calibri"
5002 id="text1343"
5003 class="st17 st18"
5004 x="935.09015"
5005 y="537.14966">2 NADPH</text>
5006 <path
5007 style="fill:none;stroke:#000000;stroke-width:2.00309992"
5008 d="m 990.8,518.11855 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 37.1,-11.1 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m -20.9,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m -56.6,11.1 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 5.6,-11.1 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 28.6,11.4 c 5.9,-1.2 4.4,-11.4 4.4,-11.4 m 42.5,11.6 -117.3,-0.2 m 10.7,-0.3 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 4.3,-11 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
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5010 inkscape:label="MVD"
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5013 style="font-size:10px;font-family:Calibri"
5014 id="text1346"
5015 class="st17 st18"
5016 x="916.46899"
5017 y="537.34601">2 H</text>
5018 <text
5019 style="font-size:10px;font-family:Calibri"
5020 id="text1348"
5021 class="st17 st18"
5022 x="975.79724"
5023 y="537.38495">3 ATP</text>
5024 <text
5025 style="font-size:10px;font-family:Calibri"
5026 id="text1350"
5027 class="st17 st18"
5028 x="1083.433"
5029 y="539.12915">2 ippPP</text>
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5031 style="font-size:10px;font-family:Calibri"
5032 id="text1352"
5033 class="st17 st18"
5034 x="1092.3324"
5035 y="502.40256">2 PPi</text>
5036 <path
5037 style="fill:none;stroke:#000000;stroke-width:1.96599996"
5038 d="m 1113.5,519.01855 -25,-0.5 m 13.7,-0.2 c -5.9,1.2 -4.4,11.4 -4.4,11.4 m 1.2,-10.6 c 5.9,-1.4 5.4,-11.9 5.4,-11.9"
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5040 inkscape:label="ARID4B_GGPS1_FDPS_FDPSP7_2"
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5043 style="font-size:10px;font-family:Calibri"
5044 id="text1355"
5045 class="st17 st18"
5046 x="1146.4008"
5047 y="536.18677">fPP</text>
5048 <text
5049 style="font-size:10px;font-family:Calibri"
5050 id="text1357"
5051 class="st17 st18"
5052 x="1147.5316"
5053 y="500.91135">15 H</text>
5054 <text
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5057 class="st17 st26"
5058 x="1166.1605"
5059 y="502.91135">2</text>
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5061 style="font-size:10px;font-family:Calibri"
5062 id="text1361"
5063 class="st17 st18"
5064 x="1169.2484"
5065 y="500.91135">O</text>
5066 <text
5067 style="font-size:10px;font-family:Calibri"
5068 id="text1363"
5069 class="st17 st18"
5070 x="1244.015"
5071 y="500.13596">2 PPi</text>
5072 <text
5073 style="font-size:10px;font-family:Calibri"
5074 id="text1365"
5075 class="st17 st18"
5076 x="1178.6937"
5077 y="500.73166">13 NADP</text>
5078 <text
5079 style="font-size:10px;font-family:Calibri"
5080 id="text1367"
5081 class="st17 st18"
5082 x="1269.6381"
5083 y="499.95636">for</text>
5084 <text
5085 style="font-size:10px;font-family:Calibri"
5086 id="text1369"
5087 class="st17 st18"
5088 x="1219.3802"
5089 y="500.49734">2 CO</text>
5090 <text
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5093 class="st17 st26"
5094 x="1238.5746"
5095 y="502.49734">2</text>
5096 <text
5097 style="font-size:10px;font-family:Calibri"
5098 id="text1373"
5099 class="st17 st18"
5100 x="1162.7885"
5101 y="536.02271">13 NADPH</text>
5102 <text
5103 style="font-size:10px;font-family:Calibri"
5104 id="text1375"
5105 class="st17 st18"
5106 x="1208.9027"
5107 y="536.07941">16 H</text>
5108 <text
5109 style="font-size:10px;font-family:Calibri"
5110 id="text1377"
5111 class="st17 st18"
5112 x="1230.308"
5113 y="535.75806">10 O</text>
5114 <text
5115 style="font-size:6.09369993px;font-family:Calibri"
5116 id="text1379"
5117 class="st17 st26"
5118 x="1249.3265"
5119 y="537.75806">2</text>
5120 <path
5121 style="fill:none;stroke:#000000;stroke-width:1.82200003"
5122 d="m 861.2,464.41855 c 5.9,-1 4.4,-9.6 4.4,-9.6 m -19,9.5 29.3,0.3 m -15.1,-0.1 c -6,1.2 -5.5,10.5 -5.5,10.5"
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5124 inkscape:label="MCAT_FASN"
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5127 style="font-size:10px;font-family:Calibri"
5128 id="text1382"
5129 class="st17 st18"
5130 x="1064.4486"
5131 y="447.78546">14 H</text>
5132 <path
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5134 d="m 888.8,422.31855 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m -27.6,0.3 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 39.9,9.6 c 7.2,-2.4 7.2,-2.4 7.2,-2.4 l -7.4,-1.9 1.9,2.1 -1.7,2.2 z"
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5136 inkscape:label="AcAcACPSynthesis f"
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5139 style="fill:none;stroke:#000000;stroke-width:1.87170005"
5140 d="m 477.8,777.11855 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m 0,-10.5 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m 0,-10.5 c 4.9,2 4.9,2 4.9,2 l -5.6,1.3 1.7,-1.6 -1,-1.7 z m -10.5,38.3 c -2.1,6.9 -2.1,6.9 -2.1,6.9 l -2.3,-6.8 2.2,1.7 2.2,-1.8 z"
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5142 inkscape:label="DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB F"
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5144 id="F_DLD_PDHX_PDHA1_DLAT_PDHA2_PDHB" /><path
5145 style="fill:none;stroke:#000000;stroke-width:2.37849998"
5146 d="m 443.6,735.91855 -27.4,0 0,127.5 116.3,0 m -60.4,0.2 c 7.3,-1.5 7.3,-12.6 7.3,-12.6 m 17.7,12.5 c -7.6,1.4 -8.5,11 -8.5,11 m -25.1,-11 c -7.6,1.4 -8.5,11 -8.5,11 m -15.9,-11 c -7.6,1.4 -8.5,11 -8.5,11 m 8.7,-11.2 c 7.3,-1.5 7.3,-12.6 7.3,-12.6"
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5148 inkscape:label="PC"
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5151 style="font-size:10px;font-family:Calibri"
5152 id="text1387"
5153 class="st17 st18"
5154 x="437.9422"
5155 y="842.4212">ADP</text>
5156 <text
5157 style="font-size:10px;font-family:Calibri"
5158 id="text1389"
5159 class="st17 st18"
5160 x="475.73709"
5161 y="842.85181">Pi</text>
5162 <text
5163 style="font-size:10px;font-family:Calibri"
5164 id="text1391"
5165 class="st17 st18"
5166 x="420.13361"
5167 y="882.27466">ATP</text>
5168 <text
5169 style="font-size:10px;font-family:Calibri"
5170 id="text1393"
5171 class="st17 st18"
5172 x="444.71021"
5173 y="881.94067">HCO</text>
5174 <text
5175 style="font-size:6.09369993px;font-family:Calibri"
5176 id="text1395"
5177 class="st17 st26"
5178 x="462.80591"
5179 y="883.94067">3</text>
5180 <text
5181 style="font-size:6.09369993px;font-family:Calibri"
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5183 class="st17 st26"
5184 x="465.89481"
5185 y="876.44067">-</text>
5186 <text
5187 style="font-size:10px;font-family:Calibri"
5188 id="text1399"
5189 class="st17 st18"
5190 x="485.21021"
5191 y="881.94067">H</text>
5192 <path
5193 style="fill:none;stroke:#000000;stroke-width:2.44919991"
5194 d="m 530.5,861.11855 c 6.9,2.1 6.9,2.1 6.9,2.1 l -6.8,2.3 1.7,-2.2 -1.8,-2.2 z m -86,-10.4 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z m 33,0 c 2,-4.9 2,-4.9 2,-4.9 l 1.3,5.6 -1.6,-1.7 -1.7,1 z"
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5200 d="m 562.6,822.11855 c 4.2,1.1 4.2,1.1 4.2,1.1 l -4.4,1.6 1.2,-1.4 -1,-1.3 z m -6.5,-9.6 c 0.1,-5.5 0.1,-5.5 0.1,-5.5 l -3.5,4.6 2.1,-0.8 1.3,1.7 z"
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5202 inkscape:label="CS f"
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5205 style="font-size:10px;font-family:Calibri"
5206 id="text1403"
5207 class="st17 st18"
5208 x="681.67023"
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5210 <text
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5212 id="text1405"
5213 class="st17 st18"
5214 x="683.4339"
5215 y="716.35669">H</text>
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5218 d="m 662.8,725.01855 c -1,6.8 -7.1,8.5 -7.1,8.5 m 45.3,-7.2 c -1,6.8 -7.1,8.5 -7.1,8.5 m -8.9,-11 c -1,6.8 -7.1,8.5 -7.1,8.5 m -39,-5.5 c 1,6.8 7.1,8.5 7.1,8.5 m -13.6,3.7 c 26,-9.2 53,-8.9 79.3,1"
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5230 d="m 632.4,755.01855 c 26,9.2 53,8.9 79.3,-1 m -74.1,13.2 c 1,-6.8 7.1,-8.5 7.1,-8.5 m 40.3,11 c -1,-6.8 -7.1,-8.5 -7.1,-8.5 m 23.1,6 c -1,-6.8 -7.1,-8.5 -7.1,-8.5 m -29.9,10.7 c -1,-6.8 -7.1,-8.5 -7.1,-8.5"
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5234 style="font-size:10px;font-family:Calibri"
5235 id="text1410"
5236 class="st17 st18"
5237 x="789.9563"
5238 y="767.94257">NADH</text>
5239 <text
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5241 id="text1412"
5242 class="st17 st18"
5243 x="814.58044"
5244 y="767.94257">+</text>
5245 <text
5246 style="font-size:10px;font-family:Calibri"
5247 id="text1414"
5248 class="st17 st18"
5249 x="789.9563"
5250 y="780.44257">H</text>
5251 <text
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5253 id="text1416"
5254 class="st17 st18"
5255 x="796.18683"
5256 y="780.44257">+</text>
5257 <text
5258 style="font-size:10px;font-family:Calibri"
5259 id="text1418"
5260 class="st17 st18"
5261 x="801.1673"
5262 y="780.44257">CO</text>
5263 <text
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5265 id="text1420"
5266 class="st17 st26"
5267 x="813.03253"
5268 y="782.44257">2</text>
5269 <text
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5271 id="text1422"
5272 class="st17 st18"
5273 x="509.7952"
5274 y="894.0257">NADH+H</text>
5275 <text
5276 style="font-size:10px;font-family:Calibri"
5277 id="text1424"
5278 class="st17 st18"
5279 x="489.20441"
5280 y="902.28931">NAD</text>
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5294 style="font-size:10px;font-family:Calibri"
5295 id="text1428"
5296 class="st17 st18"
5297 x="457.70239"
5298 y="898.8313">NADH</text>
5299 <text
5300 style="font-size:10px;font-family:Calibri"
5301 id="text1430"
5302 class="st17 st18"
5303 x="441.25998"
5304 y="898.8313">H</text>
5305 <text
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5307 id="text1432"
5308 class="st17 st18"
5309 x="415.7493"
5310 y="898.8147">CO</text>
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5314 class="st17 st26"
5315 x="427.6145"
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5320 class="st17 st18"
5321 x="503.78641"
5322 y="944.25116">NADP</text>
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5341 <text
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5343 id="text1442"
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5345 x="440.8992"
5346 y="944.5813">H</text>
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