Mercurial > repos > bitlab > bitlab
diff chromeister/README.md @ 0:ee6b15b409e5 draft
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author | bitlab |
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date | Thu, 13 Dec 2018 06:27:57 -0500 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/chromeister/README.md Thu Dec 13 06:27:57 2018 -0500 @@ -0,0 +1,36 @@ +# chromeister +An ultra fast, heuristic approach to detect conserved signals in extremely large pairwise genome comparisons. + +## Requirements + +GCC compiler (any version that is not completely outdated should do) and the R-base package (default R installation should do) with no extra packages. +Simply download the .zip and unzip it, or clone the repository (currently the active branch is "histo-kmer-ultra" DO NOT USE ANY OTHER). +Then issue the following commands: + +cd chromeister/src && make all + +You are ready to go! + +## Use + +There are several ways in which CHROMEISTER can be used. The simplest one is to run a 1-vs-1 comparison and then compute the score and the plot. +To do so, use the binaries at the bin folder: + +CHROMEISTER -query seqX -db seqY -out dotplot.mat && Rscript compute_score.R dotplot.mat + +This will generate the comparison matrix, the plot of the comparison with the automatic scoring and the guides to be used in an exhaustive GECKO comparison. + +More to be added soon! + + + + + + + + + + + + +