Mercurial > repos > cpt > cpt_gbk_to_5col
annotate BIO_FIX_TOPO.py @ 1:1bdd481d5c25 draft
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author | cpt |
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date | Mon, 05 Jun 2023 02:42:57 +0000 |
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1 import Bio.GenBank |
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2 |
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3 |
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4 def record_end(self, content): |
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5 """Clean up when we've finished the record.""" |
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6 # from Bio import Alphabet |
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7 # from Bio.Alphabet import IUPAC |
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8 from Bio.Seq import Seq, UnknownSeq |
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9 |
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10 # Try and append the version number to the accession for the full id |
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11 if not self.data.id: |
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12 assert "accessions" not in self.data.annotations, self.data.annotations[ |
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13 "accessions" |
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14 ] |
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15 self.data.id = self.data.name # Good fall back? |
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16 elif self.data.id.count(".") == 0: |
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17 try: |
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18 self.data.id += ".%i" % self.data.annotations["sequence_version"] |
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19 except KeyError: |
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20 pass |
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21 |
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22 # add the sequence information |
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23 # first, determine the alphabet |
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24 # we default to an generic alphabet if we don't have a |
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25 # seq type or have strange sequence information. |
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26 |
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27 # seq_alphabet = Alphabet.generic_alphabet |
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28 |
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29 # now set the sequence |
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30 sequence = "".join(self._seq_data) |
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31 |
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32 if ( |
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33 self._expected_size is not None |
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34 and len(sequence) != 0 |
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35 and self._expected_size != len(sequence) |
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36 ): |
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37 import warnings |
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38 from Bio import BiopythonParserWarning |
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39 |
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40 warnings.warn( |
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41 "Expected sequence length %i, found %i (%s)." |
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42 % (self._expected_size, len(sequence), self.data.id), |
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43 BiopythonParserWarning, |
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44 ) |
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45 """ |
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46 if self._seq_type: |
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47 # mRNA is really also DNA, since it is actually cDNA |
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48 if "DNA" in self._seq_type.upper() or "MRNA" in self._seq_type.upper(): |
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49 seq_alphabet = IUPAC.ambiguous_dna |
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50 # are there ever really RNA sequences in GenBank? |
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51 elif "RNA" in self._seq_type.upper(): |
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52 # Even for data which was from RNA, the sequence string |
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53 # is usually given as DNA (T not U). Bug 2408 |
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54 if "T" in sequence and "U" not in sequence: |
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55 seq_alphabet = IUPAC.ambiguous_dna |
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56 else: |
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57 seq_alphabet = IUPAC.ambiguous_rna |
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58 elif ( |
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59 "PROTEIN" in self._seq_type.upper() or self._seq_type == "PRT" |
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60 ): # PRT is used in EMBL-bank for patents |
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61 seq_alphabet = IUPAC.protein # or extended protein? |
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62 # work around ugly GenBank records which have circular or |
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63 # linear but no indication of sequence type |
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64 elif self._seq_type in ["circular", "linear", "unspecified"]: |
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65 pass |
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66 # we have a bug if we get here |
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67 else: |
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68 raise ValueError( |
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69 "Could not determine alphabet for seq_type %s" % self._seq_type |
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70 ) |
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71 |
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72 # Also save the chomosome layout |
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73 if "circular" in self._seq_type.lower(): |
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74 self.data.annotations["topology"] = "circular" |
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75 elif "linear" in self._seq_type.lower(): |
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76 self.data.annotations["topology"] = "linear" |
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77 """ |
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78 if not sequence and self.__expected_size: |
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79 self.data.seq = UnknownSeq(self._expected_size) # , seq_alphabet) |
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80 else: |
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81 self.data.seq = Seq(sequence) # , seq_alphabet) |
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82 |
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83 |
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84 Bio.GenBank._FeatureConsumer.record_end = record_end |