Mercurial > repos > davidvanzessen > argalaxy_tools
annotate report_clonality/naive_downloads.htm @ 55:2a7dc86d8f85 draft
"planemo upload commit 14f5f6a6fa8873c6d7f0f97dfddc0ba02fff3d1d"
| author | rhpvorderman | 
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| date | Fri, 19 Nov 2021 10:09:54 +0000 | 
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changeset | 1 <html> | 
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changeset | 2 | 
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changeset | 3 <head> | 
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changeset | 4 <meta http-equiv=Content-Type content="text/html; charset=windows-1252"> | 
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changeset | 5 <meta name=Generator content="Microsoft Word 14 (filtered)"> | 
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changeset | 6 <style> | 
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changeset | 7 <!-- | 
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changeset | 8 /* Font Definitions */ | 
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changeset | 9 @font-face | 
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changeset | 10 {font-family:Calibri; | 
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changeset | 11 panose-1:2 15 5 2 2 2 4 3 2 4;} | 
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changeset | 12 /* Style Definitions */ | 
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changeset | 13 p.MsoNormal, li.MsoNormal, div.MsoNormal | 
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changeset | 14 {margin-top:0in; | 
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changeset | 15 margin-right:0in; | 
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changeset | 16 margin-bottom:10.0pt; | 
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changeset | 17 margin-left:0in; | 
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changeset | 18 line-height:115%; | 
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changeset | 19 font-size:11.0pt; | 
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changeset | 20 font-family:"Calibri","sans-serif";} | 
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changeset | 21 .MsoChpDefault | 
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changeset | 22 {font-family:"Calibri","sans-serif";} | 
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changeset | 23 .MsoPapDefault | 
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changeset | 24 {margin-bottom:10.0pt; | 
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changeset | 25 line-height:115%;} | 
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changeset | 26 @page WordSection1 | 
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changeset | 27 {size:8.5in 11.0in; | 
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changeset | 28 margin:1.0in 1.0in 1.0in 1.0in;} | 
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changeset | 29 div.WordSection1 | 
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changeset | 30 {page:WordSection1;} | 
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changeset | 31 --> | 
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changeset | 32 </style> | 
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changeset | 33 | 
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changeset | 34 </head> | 
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changeset | 35 | 
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changeset | 36 <body lang=EN-US> | 
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changeset | 37 | 
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changeset | 38 <div class=WordSection1> | 
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changeset | 39 | 
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changeset | 40 <p class=MsoNormalCxSpFirst style='text-align:justify'><b><u><span | 
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changeset | 41 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Downloads | 
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changeset | 42 tab</span></u></b></p> | 
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changeset | 43 | 
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changeset | 44 <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span | 
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changeset | 45 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Description</span></b></p> | 
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changeset | 46 | 
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changeset | 47 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 48 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 49 filtered dataset:</span></u><span style='font-size:12.0pt;line-height:115%; | 
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changeset | 50 font-family:"Times New Roman","serif"'> <a name="OLE_LINK15"></a><a | 
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changeset | 51 name="OLE_LINK14">Allows you to download information on V D and J gene usage, | 
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changeset | 52 the junctions and the amino acid sequence of the sequences that passed the chosen | 
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changeset | 53 filter settings. Note: this file contains only 1 sequences of a replicate | 
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changeset | 54 sequence. </a></span></p> | 
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changeset | 55 | 
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changeset | 56 <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span | 
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changeset | 57 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Gene | 
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changeset | 58 frequencies</span></b></p> | 
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changeset | 59 | 
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changeset | 60 <p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt; | 
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changeset | 61 text-align:justify;line-height:normal'><u><span style='font-size:12.0pt; | 
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changeset | 62 font-family:"Times New Roman","serif"'>The dataset used to generate the distribution | 
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changeset | 63 of V gene families graph:</span></u><span style='font-size:12.0pt;font-family: | 
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changeset | 64 "Times New Roman","serif"'> Downloads a table with information used to generate | 
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changeset | 65 the distribution of V gene families graph.</span></p> | 
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changeset | 66 | 
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changeset | 67 <p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt; | 
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changeset | 68 text-align:justify;line-height:normal'><u><span style='font-size:12.0pt; | 
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changeset | 69 font-family:"Times New Roman","serif"'>The dataset used to generate the | 
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changeset | 70 distribution of D gene families graph: </span></u><span style='font-size:12.0pt; | 
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changeset | 71 font-family:"Times New Roman","serif"'>Downloads a table with information used | 
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changeset | 72 to generate the distribution of D gene families graph.</span></p> | 
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changeset | 73 | 
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changeset | 74 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 75 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 76 dataset used to generate the relative frequency of V gene usage graph:</span></u><span | 
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changeset | 77 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 78 Downloads the data used to generate the relative frequency of V gene usage | 
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changeset | 79 graph. In addition information on the chromosomal order of the V genes can be | 
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changeset | 80 found.</span></p> | 
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changeset | 81 | 
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changeset | 82 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 83 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 84 dataset used to generate the relative frequency of D gene usage graph:</span></u><span | 
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changeset | 85 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 86 Downloads the data used to generate the relative frequency of D gene usage | 
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changeset | 87 graph. In addition information on the chromosomal order of the D genes can be | 
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changeset | 88 found.<u> </u></span></p> | 
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changeset | 89 | 
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changeset | 90 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 91 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 92 dataset used to generate the relative frequency of J gene usage graph: </span></u><span | 
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changeset | 93 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Downloads | 
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changeset | 94 the data used to generate the relative frequency of J gene usage graph. In | 
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changeset | 95 addition information on the chromosomal order of the J genes can be found.<u> </u></span></p> | 
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changeset | 96 | 
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changeset | 97 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span lang=EN-GB | 
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changeset | 98 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; | 
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changeset | 99 color:black'>The dataset used to generate the relative frequency of the D | 
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changeset | 100 reading frame graph</span></u><span lang=EN-GB style='font-size:12.0pt; | 
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changeset | 101 line-height:115%;font-family:"Times New Roman","serif";color:black'>: Downloads | 
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changeset | 102 the data used to generate the relative frequency of the D reading frame. </span></p> | 
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changeset | 103 | 
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changeset | 104 <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span lang=EN-GB | 
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changeset | 105 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"; | 
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changeset | 106 color:black'>CDR3 characteristics</span></b></p> | 
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changeset | 107 | 
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changeset | 108 <p class=MsoNormalCxSpMiddle style='margin-bottom:0in;margin-bottom:.0001pt; | 
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changeset | 109 text-align:justify;line-height:normal'><u><span style='font-size:12.0pt; | 
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changeset | 110 font-family:"Times New Roman","serif"'>The dataset used to generate the CDR3 | 
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changeset | 111 length frequency graph:</span></u><span style='font-size:12.0pt;font-family: | 
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changeset | 112 "Times New Roman","serif"'> Downloads a table with information used for the | 
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changeset | 113 length distribution of CDR3 plot. </span></p> | 
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changeset | 114 | 
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changeset | 115 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 116 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 117 dataset used to generate the Amino Acid Composition in the CDR3 graph:</span></u><span | 
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changeset | 118 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 119 Downloads the frequency of the different amino acids in the CDR3 of all | 
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changeset | 120 filtered sequences. This data set is used for the generation of the Amino Acid | 
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changeset | 121 Composition in the CDR3 graph. In addition the order of amino acids based on hydrophobicity | 
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changeset | 122 in included. </span></p> | 
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changeset | 123 | 
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changeset | 124 <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span | 
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changeset | 125 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Heatmaps</span></b></p> | 
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changeset | 126 | 
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changeset | 127 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 128 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 129 data used to generate the VD heatmap for “donor name”:</span></u><span | 
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changeset | 130 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 131 Downloads the data set used for the generation of the VD heatmap. For each | 
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changeset | 132 uploaded donor a separate download is generated.</span></p> | 
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changeset | 133 | 
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changeset | 134 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 135 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 136 data used to generate the VJ heatmap for “donor name”:</span></u><span | 
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changeset | 137 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 138 Downloads the data set used for the generation of the VJ heatmap. For each | 
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changeset | 139 uploaded donor a separate download is generated.</span></p> | 
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changeset | 140 | 
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changeset | 141 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 142 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 143 data used to generate the DJ heatmap for “sample name”:</span></u><span | 
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changeset | 144 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 145 Downloads the data set used for the generation of the DJ heatmap. For each | 
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changeset | 146 uploaded donor a separate download is generated.</span></p> | 
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changeset | 147 | 
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changeset | 148 <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span | 
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changeset | 149 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Circos</span></b></p> | 
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changeset | 150 | 
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changeset | 151 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 152 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 153 data used to generate the VD circus plots for “donor name”:</span></u><span | 
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changeset | 154 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 155 Downloads the data set used for the generation of the VD heatmap. For each | 
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changeset | 156 uploaded donor a separate download is generated.</span></p> | 
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changeset | 157 | 
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changeset | 158 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 159 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 160 data used to generate the VJ circus plots for “donor name”:</span></u><span | 
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changeset | 161 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 162 Downloads the data set used for the generation of the VJ heatmap. For each | 
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changeset | 163 uploaded donor a separate download is generated.</span></p> | 
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changeset | 164 | 
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changeset | 165 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 166 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 167 data used to generate the DJ circus plots for “sample name”:</span></u><span | 
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changeset | 168 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> | 
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changeset | 169 Downloads the data set used for the generation of the DJ heatmap. For each | 
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changeset | 170 uploaded donor a separate download is generated.</span></p> | 
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changeset | 171 | 
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changeset | 172 <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span | 
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changeset | 173 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Clonality</span></b></p> | 
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changeset | 174 | 
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changeset | 175 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 176 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>The | 
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changeset | 177 dataset used to calculate clonality score: </span></u><span style='font-size: | 
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changeset | 178 12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Allows you to | 
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changeset | 179 download information on V D and J gene usage, the junctions and the amino acid | 
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changeset | 180 sequence of the sequences that passed the chosen filter settings. Note: this | 
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changeset | 181 file contains all the replicate sequences form the different input files.</span></p> | 
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changeset | 182 | 
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changeset | 183 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span | 
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changeset | 184 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Sequences | 
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changeset | 185 that are present in more than one replicate:</span></u><span style='font-size: | 
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changeset | 186 12.0pt;line-height:115%;font-family:"Times New Roman","serif"'> Allows you to | 
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changeset | 187 download a table containing all the sequences that were present in more than | 
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changeset | 188 one replicate. It provides the concidence type, clonaltype, sequence name, | 
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changeset | 189 replicate number, and the nucleotide sequence</span></p> | 
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changeset | 190 | 
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changeset | 191 <p class=MsoNormal> </p> | 
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changeset | 192 | 
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changeset | 193 </div> | 
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changeset | 194 | 
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changeset | 195 </body> | 
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changeset | 196 | 
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changeset | 197 </html> | 
