Mercurial > repos > davidvanzessen > shm_csr
annotate shm_frequency.htm @ 94:84e9e5c8c101 draft
"planemo upload commit d4be85014b638f1d50b318d4b735be7f6e973140"
| author | rhpvorderman |
|---|---|
| date | Fri, 24 Mar 2023 16:58:28 +0000 |
| parents | 6809c63d9161 |
| children |
| rev | line source |
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| 67 | 1 <html> |
| 2 | |
| 3 <head> | |
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6809c63d9161
"planemo upload commit fd64827ff6e63df008f6f50ddb8576ad2b1dbb26"
rhpvorderman
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4 <meta http-equiv=Content-Type content="text/html; charset=UTF-8"> |
| 67 | 5 <meta name=Generator content="Microsoft Word 14 (filtered)"> |
| 6 <style> | |
| 7 <!-- | |
| 8 /* Style Definitions */ | |
| 9 p.MsoNormal, li.MsoNormal, div.MsoNormal | |
| 10 {margin-top:0in; | |
| 11 margin-right:0in; | |
| 12 margin-bottom:10.0pt; | |
| 13 margin-left:0in; | |
| 14 line-height:115%; | |
| 15 font-size:11.0pt; | |
| 16 font-family:"Calibri","sans-serif";} | |
| 17 .MsoChpDefault | |
| 18 {font-family:"Calibri","sans-serif";} | |
| 19 .MsoPapDefault | |
| 20 {margin-bottom:10.0pt; | |
| 21 line-height:115%;} | |
| 22 @page WordSection1 | |
| 23 {size:8.5in 11.0in; | |
| 24 margin:1.0in 1.0in 1.0in 1.0in;} | |
| 25 div.WordSection1 | |
| 26 {page:WordSection1;} | |
| 27 --> | |
| 28 </style> | |
| 29 | |
| 30 </head> | |
| 31 | |
| 32 <body lang=EN-US> | |
| 33 | |
| 34 <div class=WordSection1> | |
| 35 | |
| 36 <p class=MsoNormalCxSpFirst style='text-align:justify'><b><u><span lang=EN-GB | |
| 37 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>SHM | |
| 38 frequency tab</span></u></b></p> | |
| 39 | |
| 40 <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span lang=EN-GB | |
| 41 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Graphs</span></b></p> | |
| 42 | |
| 43 <p class=MsoNormalCxSpMiddle style='text-align:justify'><span lang=EN-GB | |
| 44 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>These | |
| 45 graphs give insight into the level of SHM. The data represented in these graphs | |
| 46 can be downloaded in the download tab. <a name="OLE_LINK24"></a><a | |
| 47 name="OLE_LINK23"></a><a name="OLE_LINK90"></a><a name="OLE_LINK89">More | |
| 48 information on the values found in healthy individuals of different ages can be | |
| 49 found in IJspeert and van Schouwenburg et al, PMID: 27799928. </a></span></p> | |
| 50 | |
| 51 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span lang=EN-GB | |
| 52 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Frequency | |
| 53 scatter plot</span></u></p> | |
| 54 | |
| 55 <p class=MsoNormalCxSpMiddle style='text-align:justify'><span lang=EN-GB | |
| 56 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>A | |
| 57 dot plot showing the percentage of SHM in each transcript divided into the | |
| 58 different (sub)classes. </span><span lang=NL style='font-size:12.0pt; | |
| 59 line-height:115%;font-family:"Times New Roman","serif"'>In the graph each dot | |
| 60 represents an individual transcript.</span></p> | |
| 61 | |
| 62 <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span lang=EN-GB | |
| 63 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Mutation | |
| 64 frequency by class</span></u></p> | |
| 65 | |
| 66 <p class=MsoNormalCxSpLast style='text-align:justify'><span lang=EN-GB | |
| 67 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>A | |
| 68 bar graph showing the percentage of transcripts that contain 0%, 0-2%, 2-5%, | |
| 69 5-10% 10-15%, 15-20% or more than 20% SHM for each subclass. </span></p> | |
| 70 | |
| 71 <p class=MsoNormal><span lang=NL style='font-size:12.0pt;line-height:115%; | |
| 72 font-family:"Times New Roman","serif"'>Hanna IJspeert, Pauline A. van | |
| 73 Schouwenburg, David van Zessen, Ingrid Pico-Knijnenburg, Gertjan J. Driessen, | |
| 74 Andrew P. Stubbs, and Mirjam van der Burg (2016). </span><span | |
| 75 style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Evaluation | |
| 76 of the Antigen-Experienced B-Cell Receptor Repertoire in Healthy Children and | |
| 77 Adults. In <i>Frontiers in Immunolog, 7, pp. e410-410. </i>[<a | |
| 78 href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066086/"><span | |
| 79 style='color:windowtext'>doi:10.3389/fimmu.2016.00410</span></a>][<a | |
| 80 href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066086/"><span | |
| 81 style='color:windowtext'>Link</span></a>]</span></p> | |
| 82 | |
| 83 </div> | |
| 84 | |
| 85 </body> | |
| 86 | |
| 87 </html> |