Mercurial > repos > davidvanzessen > shm_csr
annotate baseline/script_xlsx.py @ 86:be36df6dd589 draft
"planemo upload commit 78ace939ed7437b8b360588032449a99aad949eb"
author | rhpvorderman |
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date | Wed, 27 Oct 2021 10:02:33 +0000 |
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1 import xlrd |
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2 import argparse |
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3 |
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4 parser = argparse.ArgumentParser() |
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5 parser.add_argument("--input", help="Excel input file containing one or more sheets where column G has the gene annotation, H has the sequence id and J has the sequence") |
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6 parser.add_argument("--ref", help="Reference file") |
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7 parser.add_argument("--output", help="Output file") |
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8 |
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9 args = parser.parse_args() |
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10 |
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11 gene_column = 6 |
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12 id_column = 7 |
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13 seq_column = 8 |
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14 LETTERS = [x for x in "ABCDEFGHIJKLMNOPQRSTUVWXYZ"] |
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15 |
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16 |
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17 refdic = dict() |
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18 with open(args.ref, 'r') as ref: |
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19 currentSeq = "" |
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20 currentId = "" |
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21 for line in ref.readlines(): |
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22 if line[0] is ">": |
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23 if currentSeq is not "" and currentId is not "": |
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24 refdic[currentId[1:]] = currentSeq |
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25 currentId = line.rstrip() |
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26 currentSeq = "" |
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27 else: |
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28 currentSeq += line.rstrip() |
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29 refdic[currentId[1:]] = currentSeq |
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30 |
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31 currentSeq = "" |
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32 currentId = "" |
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33 with xlrd.open_workbook(args.input, 'r') as wb: |
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34 with open(args.output, 'a') as o: |
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35 for sheet in wb.sheets(): |
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36 if sheet.cell(1,gene_column).value.find("IGHV") < 0: |
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37 print("Genes not in column " + LETTERS[gene_column] + ", skipping sheet " + sheet.name) |
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38 continue |
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39 o.write(">>>" + sheet.name + "\n") |
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40 outputdic = dict() |
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41 for rowindex in range(1, sheet.nrows): |
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42 ref = sheet.cell(rowindex, gene_column).value.replace(">", "") |
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43 if ref in outputdic: |
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44 outputdic[ref] += [(sheet.cell(rowindex, id_column).value.replace(">", ""), sheet.cell(rowindex, seq_column).value)] |
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45 else: |
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46 outputdic[ref] = [(sheet.cell(rowindex, id_column).value.replace(">", ""), sheet.cell(rowindex, seq_column).value)] |
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47 #print outputdic |
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48 |
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49 for k in list(outputdic.keys()): |
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50 if k in refdic: |
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51 o.write(">>" + k + "\n") |
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52 o.write(refdic[k] + "\n") |
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53 for seq in outputdic[k]: |
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54 #print seq |
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55 o.write(">" + seq[0] + "\n") |
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56 o.write(seq[1] + "\n") |
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57 else: |
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58 print(k + " not in reference, skipping " + k) |