Mercurial > repos > davidvanzessen > shm_csr
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author | davidvanzessen |
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date | Wed, 06 Dec 2017 09:55:37 -0500 |
parents | a24f8c93583a |
children | ba33b94637ca |
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<html> <head> <meta http-equiv=Content-Type content="text/html; charset=windows-1252"> <meta name=Generator content="Microsoft Word 14 (filtered)"> <style> <!-- /* Style Definitions */ p.MsoNormal, li.MsoNormal, div.MsoNormal {margin-top:0in; margin-right:0in; margin-bottom:10.0pt; margin-left:0in; line-height:115%; font-size:11.0pt; font-family:"Calibri","sans-serif";} .MsoChpDefault {font-family:"Calibri","sans-serif";} .MsoPapDefault {margin-bottom:10.0pt; line-height:115%;} @page WordSection1 {size:8.5in 11.0in; margin:1.0in 1.0in 1.0in 1.0in;} div.WordSection1 {page:WordSection1;} --> </style> </head> <body lang=EN-US> <div class=WordSection1> <p class=MsoNormalCxSpFirst style='text-align:justify'><b><u><span lang=EN-GB style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>SHM frequency tab</span></u></b></p> <p class=MsoNormalCxSpMiddle style='text-align:justify'><b><span lang=EN-GB style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Graphs</span></b></p> <p class=MsoNormalCxSpMiddle style='text-align:justify'><span lang=EN-GB style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>These graphs give insight into the level of SHM. The data represented in these graphs can be downloaded in the download tab. <a name="OLE_LINK24"></a><a name="OLE_LINK23"></a><a name="OLE_LINK90"></a><a name="OLE_LINK89">More information on the values found in healthy individuals of different ages can be found in IJspeert and van Schouwenburg et al, PMID: 27799928. </a></span></p> <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span lang=EN-GB style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Frequency scatter plot</span></u></p> <p class=MsoNormalCxSpMiddle style='text-align:justify'><span lang=EN-GB style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>A dot plot showing the percentage of SHM in each transcript divided into the different (sub)classes. </span><span lang=NL style='font-size:12.0pt; line-height:115%;font-family:"Times New Roman","serif"'>In the graph each dot represents an individual transcript.</span></p> <p class=MsoNormalCxSpMiddle style='text-align:justify'><u><span lang=EN-GB style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Mutation frequency by class</span></u></p> <p class=MsoNormalCxSpLast style='text-align:justify'><span lang=EN-GB style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>A bar graph showing the percentage of transcripts that contain 0%, 0-2%, 2-5%, 5-10% 10-15%, 15-20% or more than 20% SHM for each subclass. </span></p> <p class=MsoNormal><span lang=NL style='font-size:12.0pt;line-height:115%; font-family:"Times New Roman","serif"'>Hanna IJspeert, Pauline A. van Schouwenburg, David van Zessen, Ingrid Pico-Knijnenburg, Gertjan J. Driessen, Andrew P. Stubbs, and Mirjam van der Burg (2016). </span><span style='font-size:12.0pt;line-height:115%;font-family:"Times New Roman","serif"'>Evaluation of the Antigen-Experienced B-Cell Receptor Repertoire in Healthy Children and Adults. In <i>Frontiers in Immunolog, 7, pp. e410-410. </i>[<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066086/"><span style='color:windowtext'>doi:10.3389/fimmu.2016.00410</span></a>][<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066086/"><span style='color:windowtext'>Link</span></a>]</span></p> </div> </body> </html>