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| author | dcouvin |
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| date | Wed, 08 Dec 2021 01:46:07 +0000 |
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#Gene_ID Gene_name Codon_pos Ref_nuc Ref_codon Res_codon Resistance PMID Mechanism Notes Required_mut #rrs rrs 514 A A C AMIKACIN 23561273;22479378 #rrs rrs 517 C C T AMIKACIN,STREPTOMYCIN 23561273;23995137;23906937;19209951 rrs rrs 517 C C T STREPTOMYCIN 23561273;23995137;23906937;19209951 rrs rrs 1158 G G T AMIKACIN 22479378 rrs rrs 1338 A A C AMIKACIN 22479378 #rrs rrs 1401 A A G AMIKACIN,CAPREOMYCIN,KANAMYCIN,STREPTOMYCIN 23561273;23995137;23288402;23705640;22461677;22479378;23166667;19209951;23906937 rrs rrs 1401 A A G AMIKACIN,CAPREOMYCIN,KANAMYCIN 23561273;23995137;23288402;23705640;22461677;22479378;23166667;19209951;23906937 rrs rrs 1402 C C A,T AMIKACIN,CAPREOMYCIN,KANAMYCIN 23705640;19209951,23288402;23705640;22479378;19209951 rrs rrs 1484 G G T AMIKACIN,CAPREOMYCIN,KANAMYCIN,STREPTOMYCIN 22479378;23166667;19209951;23906937 Rv0678 Rv0678 138 GAG E G BEDAQUILINE,CLOFAZIMINE 25010492 Rv0678 Rv0678 94 CGG R Q BEDAQUILINE,CLOFAZIMINE 25010492 Rv0678 Rv0678 68 AGC S G BEDAQUILINE,CLOFAZIMINE 25010492 Rv0678 Rv0678 63 AGC S R BEDAQUILINE,CLOFAZIMINE 24590481 Rv0678 Rv0678 134 CGA R * BEDAQUILINE,CLOFAZIMINE 24590481 tlyA tlyA 3 CGA R * CAPREOMYCIN 19209951 tlyA tlyA 14 CGG R W CAPREOMYCIN 19209951 tlyA tlyA 18 CGA R * CAPREOMYCIN 19209951 tlyA tlyA 22 CAG Q * CAPREOMYCIN 19209951 tlyA tlyA 67 GCG A E CAPREOMYCIN 19209951 tlyA tlyA 69 AAA K E CAPREOMYCIN 19209951 tlyA tlyA 91 GCA A E CAPREOMYCIN 19209951 tlyA tlyA 118 CTG L P CAPREOMYCIN 19209951 tlyA tlyA 128 GTG V E CAPREOMYCIN 19209951 tlyA tlyA 150 CTG L P CAPREOMYCIN 19209951 tlyA tlyA 183 CCG P L CAPREOMYCIN 19209951 tlyA tlyA 184 CAG Q * CAPREOMYCIN 19209951 tlyA tlyA 185 TTT F L CAPREOMYCIN 19209951 tlyA tlyA 236 AAT N K CAPREOMYCIN 19209951 tlyA tlyA 238 GAG E K CAPREOMYCIN 19209951 embA_promoter_size_115bp embA 4 GAC D N ETHAMBUTOL 19209951 embA_promoter_size_115bp embA 321 GGC G S ETHAMBUTOL 19209951 embA_promoter_size_115bp embA 350 GGC G D ETHAMBUTOL 19209951 embA_promoter_size_115bp embA 462 GCG A V ETHAMBUTOL 19209951 embA_promoter_size_115bp embA 833 GAC D A ETHAMBUTOL 19209951 embB embB 221 GCG A G ETHAMBUTOL 19209951 embB embB 225 GCG A S ETHAMBUTOL 19209951 embB embB 227 GTG V G ETHAMBUTOL 19209951 embB embB 239 CTG L P ETHAMBUTOL 19209951 embB embB 240 GAC D H ETHAMBUTOL 19209951 embB embB 257 CGG R W ETHAMBUTOL 19209951 embB embB 271 GCA A V ETHAMBUTOL 19209951 embB embB 272 AGC S C,I ETHAMBUTOL 19209951,19209951 embB embB 274 CGC R P ETHAMBUTOL 19209951 embB embB 281 GCC A P ETHAMBUTOL 19209951 embB embB 282 GTG V L,G ETHAMBUTOL 19209951,19209951 embB embB 285 TTC F L ETHAMBUTOL 19209951 embB embB 287 TTC F V,C ETHAMBUTOL 19209951,19209951 embB embB 293 ATC I N ETHAMBUTOL 19209951 embB embB 294 GGC G S ETHAMBUTOL 19209951 embB embB 296 AAT N H,K ETHAMBUTOL 19209951,19209951 embB embB 297 TCG S A,L ETHAMBUTOL 19209951,19209951 embB embB 298 TCG S W ETHAMBUTOL 23561273 embB embB 299 GAC D E ETHAMBUTOL 19209951 embB embB 306 ATG M L,V,T,I ETHAMBUTOL 23995136;24055765;22461677;19209951,23995137;23995136;22461677;23166667;19209951,19209951,23995137;23995136;24055765;22461677;23166667;19209951 embB embB 309 GTC V G ETHAMBUTOL 19209951 embB embB 311 GAC D H,G ETHAMBUTOL 19209951,23561273 embB embB 312 CAC H R ETHAMBUTOL 19209951 embB embB 313 GCC A V ETHAMBUTOL 23995137;22461677 embB embB 314 GGC G A ETHAMBUTOL 19209951 embB embB 315 TAC Y C ETHAMBUTOL 22461677 embB embB 317 TCC S T ETHAMBUTOL 19209951 embB embB 318 AAC N H,S,K ETHAMBUTOL 19209951,19209951,19209951 embB embB 319 TAT Y N,S,C ETHAMBUTOL 19209951,19209951,23561273;19209951 embB embB 320 TTC F L ETHAMBUTOL 23561273 embB embB 328 GAT D Y,V,G ETHAMBUTOL 19209951,23561273;19209951,23561273;19209951 embB embB 330 TTC F V ETHAMBUTOL 19209951 embB embB 331 GGC G R ETHAMBUTOL 19209951 embB embB 332 TGG W L ETHAMBUTOL 19209951 embB embB 333 TAT Y H ETHAMBUTOL 19209951 embB embB 334 TAC Y H ETHAMBUTOL 19209951 embB embB 347 AGT S C,I,T ETHAMBUTOL 23561273,19209951,19209951 embB embB 354 GAC D A ETHAMBUTOL 23561273;23995137;23995136 embB embB 356 GCC A S,V ETHAMBUTOL 19209951,19209951 embB embB 357 GCC A S,V ETHAMBUTOL 19209951,19209951 embB embB 358 GGG G V ETHAMBUTOL 19209951 embB embB 359 CTA L I ETHAMBUTOL 19209951 embB embB 360 GTG V M ETHAMBUTOL 19209951 embB embB 366 TCG S P ETHAMBUTOL 19209951 embB embB 367 CGT R P ETHAMBUTOL 19209951 embB embB 368 GAG E Q,A,D ETHAMBUTOL 19209951,19209951,19209951 embB embB 369 GTG V L,A ETHAMBUTOL 19209951,19209951 embB embB 370 CTG L R ETHAMBUTOL 19209951 embB embB 371 CCC P R ETHAMBUTOL 19209951 embB embB 374 GGG G V ETHAMBUTOL 19209951 embB embB 375 CCG P A ETHAMBUTOL 19209951 embB embB 377 GTG V M,G ETHAMBUTOL 19209951,19209951 #embB embB 378 GAG E K,A ETHAMBUTOL 19209951,23995136;19209951 embB embB 378 GAG E K ETHAMBUTOL 19209951 embB embB 379 GCC A T,D ETHAMBUTOL 19209951,19209951 embB embB 380 AGC S R,N ETHAMBUTOL 19209951,23561273 embB embB 384 TAC Y N ETHAMBUTOL 19209951 embB embB 388 GCC A G ETHAMBUTOL 19209951 embB embB 395 TGG W R,C ETHAMBUTOL 19209951,19209951 embB embB 397 CCG P T,Q ETHAMBUTOL 19209951,19209951 embB embB 398 TTC F Y ETHAMBUTOL 19209951 embB embB 399 AAC N H,D ETHAMBUTOL 19209951,19209951 embB embB 400 AAC N K ETHAMBUTOL 19209951 embB embB 401 GGC G S ETHAMBUTOL 19209951 embB embB 404 CCG P S ETHAMBUTOL 23561273 embB embB 405 GAG E D ETHAMBUTOL 23561273 embB embB 406 GGC G S,C,D,A ETHAMBUTOL 23561273;23995136;24055765;19209951,23995136;24055765;19209951,23561273;23995136;24055765;19209951,23561273;24055765;19209951 embB embB 412 TCG S L ETHAMBUTOL 23561273 embB embB 423 ATG M I ETHAMBUTOL 19209951 embB embB 430 CCG P L ETHAMBUTOL 19209951 embB embB 431 GCG A T ETHAMBUTOL 19209951 embB embB 435 GTC V G ETHAMBUTOL 19209951 embB embB 436 GTT V G ETHAMBUTOL 19209951 embB embB 437 ACC T A ETHAMBUTOL 19209951 embB embB 446 CCC P H ETHAMBUTOL 19209951 embB embB 448 GGC G V ETHAMBUTOL 19209951 embB embB 452 GTG V L ETHAMBUTOL 19209951 embB embB 459 GGC G A ETHAMBUTOL 19209951 embB embB 460 CGC R C,L ETHAMBUTOL 19209951,19209951 embB embB 461 CCG P S ETHAMBUTOL 19209951 embB embB 469 CGT R P ETHAMBUTOL 19209951 embB embB 471 CGC R P ETHAMBUTOL 19209951 embB embB 482 ATG M I ETHAMBUTOL 23561273 embB embB 497 CAG Q K,P,R ETHAMBUTOL 23561273;19209951,23561273,23561273;23995137;23995136;24055765;19209951 embB embB 504 GAA E D ETHAMBUTOL 23561273;23995137 embB embB 507 AGG R K ETHAMBUTOL 23561273 embB embB 659 GCG A T ETHAMBUTOL 19209951 embB embB 745 GGC G D ETHAMBUTOL 19209951 embB embB 853 CAG Q P ETHAMBUTOL 23995136 embB embB 959 GAC D A ETHAMBUTOL 19209951 embB embB 1000 ATG M R ETHAMBUTOL 19209951 embB embB 1002 CAC H R ETHAMBUTOL 23995137 embB embB 1024 GAC D N ETHAMBUTOL 19209951 #embB embB 1082 ACC T A ETHAMBUTOL 23995136 embC embC 187 GAG E E ETHAMBUTOL 23995136 embC embC 244 GCC A T ETHAMBUTOL 19209951 embC embC 247 GCG A P ETHAMBUTOL 19209951 embC embC 251 CTG L R ETHAMBUTOL 19209951 embC embC 254 GCC A G ETHAMBUTOL 19209951 #embC embC 270 ACC T I ETHAMBUTOL 23995136;24055765;19209951 embC embC 272 GGT G S ETHAMBUTOL 19209951 embC embC 285 CAT H Y ETHAMBUTOL 19209951 embC embC 287 GTC V F ETHAMBUTOL 19209951 embC embC 288 GGG G W,V ETHAMBUTOL 19209951,19209951 embC embC 296 TAC Y H,S ETHAMBUTOL 19209951,19209951 embC embC 297 ATC I L,T ETHAMBUTOL 19209951,19209951 embC embC 300 ATG M R ETHAMBUTOL 19209951 embC embC 302 CGG R G ETHAMBUTOL 19209951 embC embC 303 GTG V G ETHAMBUTOL 19209951 embC embC 307 GCG A T ETHAMBUTOL 19209951 embC embC 308 GGC G D ETHAMBUTOL 19209951 embC embC 309 TAT Y N ETHAMBUTOL 19209951 embC embC 310 ATG M K ETHAMBUTOL 19209951 embC embC 325 GGC G S ETHAMBUTOL 19209951 embC embC 326 TGG W R ETHAMBUTOL 19209951 embC embC 327 TAC Y N ETHAMBUTOL 19209951 embC embC 779 GCC A V ETHAMBUTOL 23995136 embR embR 379 CAG Q R ETHAMBUTOL 19209951 embR embR 369 ATT I T ETHAMBUTOL 19209951 embR embR 356 CGA R G ETHAMBUTOL 19209951 embR embR 350 GTG V G ETHAMBUTOL 19209951 embR embR 326 AGC S N ETHAMBUTOL 19209951 embR embR 320 CTA L V ETHAMBUTOL 19209951 embR embR 292 CTG L M ETHAMBUTOL 19209951 embR embR 240 GGC G R ETHAMBUTOL 19209951 embR embR 230 CGG R W ETHAMBUTOL 19209951 embR embR 223 GAT D E ETHAMBUTOL 19209951 embR embR 211 CTG L M ETHAMBUTOL 19209951 embR embR 200 GAA E A ETHAMBUTOL 19209951 embR embR 188 AGC S R ETHAMBUTOL 19209951 embR embR 187 GCC A V ETHAMBUTOL 19209951 embR embR 186 CGG R G ETHAMBUTOL 19209951 embR embR 176 GCC A V ETHAMBUTOL 19209951 embR embR 172 CTT L R ETHAMBUTOL 19209951 embR embR 53 GAC D H ETHAMBUTOL 19209951 embR embR 32 ACC T P ETHAMBUTOL 19209951 embR embR 7 GTG V G ETHAMBUTOL 19209951 embA_promoter_size_115bp embA_promoter -16 C C T ETHAMBUTOL 19209951 embA_promoter_size_115bp embA_promoter -12 C C T ETHAMBUTOL 19209951 embA_promoter_size_115bp embA_promoter -11 C C A ETHAMBUTOL 19209951 ethA_promoter_size_74bp ethA 463 CGT R S ETHIONAMIDE 14638486;19209951 ethA_promoter_size_74bp ethA 461 TAC Y H ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 413 GGT G D ETHIONAMIDE 14638486;19209951 ethA_promoter_size_74bp ethA 403 TGT C G ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 397 CTG L R ETHIONAMIDE 19486070 ethA_promoter_size_74bp ethA 392 ACG T A ETHIONAMIDE 14638486;19209951 ethA_promoter_size_74bp ethA 386 TAC Y C ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 385 GGC G D ETHIONAMIDE 14638486;19209951 ethA_promoter_size_74bp ethA 381 GCC A P ETHIONAMIDE 10944230;19209951 ethA_promoter_size_74bp ethA 342 ACG T K ETHIONAMIDE 10944230;19209951 ethA_promoter_size_74bp ethA 338 ATC I S ETHIONAMIDE 14638486;19209951 ethA_promoter_size_74bp ethA 333 CTG L R ETHIONAMIDE 19486070 ethA_promoter_size_74bp ethA 329 TCA S L ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 272 CTA L P ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 269 CAG Q * ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 246 CAG Q * ETHIONAMIDE 14638486;19209951 ethA_promoter_size_74bp ethA 232 ACC T A ETHIONAMIDE 19486070 ethA_promoter_size_74bp ethA 223 GAG E K ETHIONAMIDE 19209951 ethA_promoter_size_74bp ethA 186 ACG T K ETHIONAMIDE 10944230;19209951 ethA_promoter_size_74bp ethA 165 CAG Q P ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 84 TAC Y D ETHIONAMIDE 10944230;19209951 ethA_promoter_size_74bp ethA 61 ACG T M ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 58 GAC D A ETHIONAMIDE 10944230;19209951 ethA_promoter_size_74bp ethA 51 CCC P L ETHIONAMIDE 19209951 ethA_promoter_size_74bp ethA 43 GGC G C,S ETHIONAMIDE 19209951,10944230;14638486;19209951 ethA_promoter_size_74bp ethA 22 CAC H P ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 11 GGC G A ETHIONAMIDE 20974869 ethA_promoter_size_74bp ethA 1 ATG M R ETHIONAMIDE 20974869 ethR ethR 95 GCC A T ETHIONAMIDE 20974869 ethR ethR 110 TTC F L ETHIONAMIDE 20974869 inhA inhA 21 ATC I T ETHIONAMIDE 10944230 inhA inhA 94 TCG S A ETHIONAMIDE 20974869;19209951 fabG1_promoter_size_223bp fabG1_promoter -17 G G T ETHIONAMIDE,ISONIAZID 19209951;23561273;22461677 fabG1_promoter_size_223bp fabG1_promoter -15 C C T ETHIONAMIDE,ISONIAZID 10944230;19209951;23561273;19486070;Wang_et_al._2013;10884617;22461677;Jin_et_al._2012 fabG1_promoter_size_223bp fabG1_promoter -8 T T C ETHIONAMIDE 20974869 gyrA gyrA 68 CGC R G FLUOROQUINOLONE 23561273 gyrA gyrA 69 AGC S T FLUOROQUINOLONE 23561273 gyrA gyrA 70 CAC H R FLUOROQUINOLONE 23705640;22279180 gyrA gyrA 74 GCC A S FLUOROQUINOLONE 24055765;23705640;22279180;19209951 #gyrA gyrA 80 ACC T A FLUOROQUINOLONE 23705640;22279180;19209951 gyrA gyrA 88 GGC G C,A FLUOROQUINOLONE 24055765;23705640;22279180,24055765;23705640;22279180;19209951 gyrA gyrA 89 GAC D N FLUOROQUINOLONE 23561273;22461677;22279180;19209951 gyrA gyrA 90 GCG A E,V,G FLUOROQUINOLONE 22279180,23561273;23995137;24055765;23288402;23906937;23705640;22461677;22279180;23166667;19209951,23705640;22279180;19209951 gyrA gyrA 91 TCG S P,A FLUOROQUINOLONE 23561273;23288402;23906937;23705640;22461677;22279180;23166667;19209951,23561273;22279180 gyrA gyrA 92 ATC I M FLUOROQUINOLONE 22279180 gyrA gyrA 94 GAC D N,Y,H,V,A,G FLUOROQUINOLONE 23561273;23995137;23288402;23906937;23705640;22461677;22279180;23166667;19209951,23561273;23288402;23705640;22461677;22279180;23166667;19209951,23561273;24055765;23288402;23906937;23705640;22461677;22279180;23166667;19209951,24055765;23705640;22279180;19209951,23288402;23705640;22461677;22279180;23166667;19209951,23561273;24055765;23288402;23906937;23705640;22461677;22279180;23166667;19209951 gyrA gyrA 102 CCC P H FLUOROQUINOLONE 23705640;22279180;19209951 gyrA gyrA 109 CTG L V FLUOROQUINOLONE 22279180;19209951 gyrB gyrB 90 GCC A G FLUOROQUINOLONE 23995137 gyrB gyrB 446 CGT R C,H,L FLUOROQUINOLONE 23995137;19209951,23705640,23705640 gyrB gyrB 447 TCC S F FLUOROQUINOLONE 23705640;22279180;19209951 gyrB gyrB 461 GAC D N,H,A FLUOROQUINOLONE 24055765;23705640;22279180;19209951,24055765;23705640;22279180;19209951,24055765;23705640;22279180;19209951 gyrB gyrB 470 GGT G C,A FLUOROQUINOLONE 23705640,23705640;22279180;19209951 gyrB gyrB 486 ATC I L FLUOROQUINOLONE 23705640 gyrB gyrB 494 GAC D A FLUOROQUINOLONE 23705640;19209951 gyrB gyrB 499 AAC N Y,D,T,K FLUOROQUINOLONE 23705640,24055765;23705640;19209951,24055765;23705640;22279180;19209951,24055765;23705640 gyrB gyrB 500 ACC T P,N,I FLUOROQUINOLONE 24055765;23705640;22279180;19209951,24055765;23705640,23705640 gyrB gyrB 501 GAA E V,D FLUOROQUINOLONE 24055765;23705640;22279180;19209951,24055765;23705640;22279180 gyrB gyrB 504 GCG A T,V FLUOROQUINOLONE 23705640;22279180;19209951,24055765;23705640;19209951 gyrB gyrB 507 ACG T M FLUOROQUINOLONE 24055765 gyrB gyrB 538 CAA Q H FLUOROQUINOLONE 22279180;19209951 gyrB gyrB 670 GTT V F FLUOROQUINOLONE 23995137 ahpC_promoter_size_180bp ahpC 2 CCA P S ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC 5 ACC T I ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC 10 TTC F I ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC 33 GAC D N ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC 73 GAC D H ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC 76 GAG E K ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC 191 CTC L R ISONIAZID 19209951 inhA inhA 8 AAA K N ISONIAZID 19209951 inhA inhA 11 CTG L V ISONIAZID 19486070 inhA inhA 16 ATC I T ISONIAZID 10884617;19209951 inhA inhA 21 ATC I V,N,T ISONIAZID 19486070;10884617;19209951,19486070,19209951 inhA inhA 40 GGG G W ISONIAZID 19486070 inhA inhA 47 ATT I T ISONIAZID 10884617;19209951 #inhA inhA 78 GTG V A ISONIAZID 19209951 inhA inhA 94 TCG S A,L,W ISONIAZID 19486070;23995137;24055765;10884617;19209951,19209951,19486070 inhA inhA 95 ATT I P,T ISONIAZID 24731071,19209951 inhA inhA 194 ATC I T ISONIAZID 19209951 kasA kasA 66 GAT D N ISONIAZID 10884617;19209951 kasA kasA 77 ATG M I ISONIAZID 19209951 kasA kasA 121 AGG R K ISONIAZID 10884617;19209951 #kasA kasA 269 GGT G S ISONIAZID 10884617;19209951 #kasA kasA 312 GGC G S ISONIAZID 10884617;19209951 kasA kasA 387 GGC G D ISONIAZID 10884617;19209951 kasA kasA 413 TTC F L ISONIAZID 10884617;19209951 katG_promoter_size_107bp katG 735 GAC D A,N ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 728 TGG W C ISONIAZID 19209951 katG_promoter_size_107bp katG 727 GCC A D ISONIAZID 19209951 katG_promoter_size_107bp katG 717 CAG Q P ISONIAZID 19209951 katG_promoter_size_107bp katG 716 GCG A P ISONIAZID 19209951 katG_promoter_size_107bp katG 713 GCC A P ISONIAZID 19209951 katG_promoter_size_107bp katG 710 GTC V A ISONIAZID 19209951 katG_promoter_size_107bp katG 700 TCC S P ISONIAZID 19209951 katG_promoter_size_107bp katG 695 GAC D A ISONIAZID 19209951 katG_promoter_size_107bp katG 685 GGC G R ISONIAZID 19209951 katG_promoter_size_107bp katG 653 CTG L P ISONIAZID 19209951 katG_promoter_size_107bp katG 636 GCA A E ISONIAZID 19209951 katG_promoter_size_107bp katG 634 CTC L F ISONIAZID 19209951 katG_promoter_size_107bp katG 629 GGT G S ISONIAZID 10884617;19209951 katG_promoter_size_107bp katG 619 CTC L P ISONIAZID 19209951 katG_promoter_size_107bp katG 609 ATG M I ISONIAZID 19209951 katG_promoter_size_107bp katG 607 GAG E K ISONIAZID 19209951 katG_promoter_size_107bp katG 593 GGC G D ISONIAZID 19209951 katG_promoter_size_107bp katG 589 CCC P T ISONIAZID 19209951 katG_promoter_size_107bp katG 587 CTG L P,M ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 574 GCG A V,E ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 573 GAT D N ISONIAZID 19209951 katG_promoter_size_107bp katG 567 TTC F S ISONIAZID 19209951 katG_promoter_size_107bp katG 551 GCC A G ISONIAZID 19209951 katG_promoter_size_107bp katG 550 GCC A D ISONIAZID 19209951 katG_promoter_size_107bp katG 529 AAC N D ISONIAZID 19209951 katG_promoter_size_107bp katG 525 CAG Q P ISONIAZID 19209951 katG_promoter_size_107bp katG 515 CGC R C ISONIAZID 19209951 katG_promoter_size_107bp katG 505 TGG W S,R ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 502 CAA Q H ISONIAZID 19209951 katG_promoter_size_107bp katG 496 CGC R L ISONIAZID 23561273 katG_promoter_size_107bp katG 491 GGC G C ISONIAZID 19209951 katG_promoter_size_107bp katG 488 AAG K N ISONIAZID 19209951 katG_promoter_size_107bp katG 485 GGT G V ISONIAZID 23561273;19209951 katG_promoter_size_107bp katG 484 CGT R S ISONIAZID 19209951 katG_promoter_size_107bp katG 477 TGG W * ISONIAZID 19209951 katG_promoter_size_107bp katG 473 GTT V F ISONIAZID 23561273 katG_promoter_size_107bp katG 464 GCA A S ISONIAZID 23561273 katG_promoter_size_107bp katG 463 CGG R W ISONIAZID 23561273 katG_promoter_size_107bp katG 462 ATC I T ISONIAZID 19209951 katG_promoter_size_107bp katG 461 CAG Q P ISONIAZID 23561273 katG_promoter_size_107bp katG 459 AAG K * ISONIAZID 23561273 katG_promoter_size_107bp katG 457 AGC S I ISONIAZID 19209951 katG_promoter_size_107bp katG 454 GAG E R ISONIAZID 24731071 katG_promoter_size_107bp katG 449 CTC L F ISONIAZID 19209951 katG_promoter_size_107bp katG 444 GCG A T ISONIAZID 19209951 katG_promoter_size_107bp katG 435 ACC T I ISONIAZID 23561273 katG_promoter_size_107bp katG 434 CAG Q * ISONIAZID 19209951 katG_promoter_size_107bp katG 429 CCG P S ISONIAZID 19209951 katG_promoter_size_107bp katG 428 GGG G R ISONIAZID 23561273 katG_promoter_size_107bp katG 424 GCG A V,E,G ISONIAZID 19209951,19209951,19486070 katG_promoter_size_107bp katG 419 GAC D H ISONIAZID 23561273;19209951 katG_promoter_size_107bp katG 418 CGA R L,Q ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 414 AAG K N ISONIAZID 19209951 katG_promoter_size_107bp katG 413 TAC Y H ISONIAZID 19209951 katG_promoter_size_107bp katG 409 GCC A D,R ISONIAZID 19209951,24731071 katG_promoter_size_107bp katG 397 TGG W * ISONIAZID 19209951 katG_promoter_size_107bp katG 394 ACG T A ISONIAZID 19209951 katG_promoter_size_107bp katG 393 ATC I N ISONIAZID 19209951 katG_promoter_size_107bp katG 384 CTG L R ISONIAZID 19209951 katG_promoter_size_107bp katG 381 GAC D G ISONIAZID 19209951 katG_promoter_size_107bp katG 380 ACT T I ISONIAZID 23561273;19209951 katG_promoter_size_107bp katG 379 GCC A V ISONIAZID 19209951 katG_promoter_size_107bp katG 378 CTG L P ISONIAZID 19209951 katG_promoter_size_107bp katG 365 CCG P L ISONIAZID 23561273 katG_promoter_size_107bp katG 361 GCC A D ISONIAZID 19209951 katG_promoter_size_107bp katG 357 GAC D N,H ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 352 CAA Q * ISONIAZID 19486070;19209951 katG_promoter_size_107bp katG 350 GCT A S,T ISONIAZID 10884617;19209951,19209951 katG_promoter_size_107bp katG 345 AAG K T ISONIAZID 19209951 katG_promoter_size_107bp katG 341 TGG W S ISONIAZID 19209951 katG_promoter_size_107bp katG 337 TAC Y F,C ISONIAZID 19209951,23561273;19209951 katG_promoter_size_107bp katG 336 CTG L R ISONIAZID 19209951 katG_promoter_size_107bp katG 335 ATC I T,V ISONIAZID 19209951,23561273;19209951 katG_promoter_size_107bp katG 331 AGT S C ISONIAZID 19209951 katG_promoter_size_107bp katG 328 TGG W C,L,S,G ISONIAZID 19209951,19209951,19486070;19209951,19209951 katG_promoter_size_107bp katG 326 ACG T M ISONIAZID 23561273 katG_promoter_size_107bp katG 324 ACC T P ISONIAZID 19209951 katG_promoter_size_107bp katG 321 TGG W C,*,L,S,R ISONIAZID 19209951,19209951,19209951,19209951;24731071,19209951 katG_promoter_size_107bp katG 318 GAG E V ISONIAZID 24731071 katG_promoter_size_107bp katG 317 ATC I V,L ISONIAZID 23561273,19209951 katG_promoter_size_107bp katG 316 GGC G D,S ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 315 AGC S R,I,N,T,G,L ISONIAZID Wang_et_al._2013;10884617;22461677;19209951,19209951,23561273;19486070;22461677;19209951,23561273;19486070;23995137;24055765;Wang_et_al._2013;10884617;22461677;Jin_et_al._2012;19209951;24731071,23561273;19209951,24731071 katG_promoter_size_107bp katG 311 GAC D E,G,Y ISONIAZID 19209951,19209951,19209951 katG_promoter_size_107bp katG 309 GGT G D,C,S ISONIAZID 19209951,19209951,19209951 katG_promoter_size_107bp katG 308 ACC T P ISONIAZID 19209951 katG_promoter_size_107bp katG 307 GGA G E,A,R ISONIAZID 19209951,19209951,19209951 katG_promoter_size_107bp katG 305 GGC G A ISONIAZID 19209951 katG_promoter_size_107bp katG 304 TAT Y S ISONIAZID 19209951 katG_promoter_size_107bp katG 302 AGC S R ISONIAZID 19209951 katG_promoter_size_107bp katG 300 TGG W *,G ISONIAZID 19209951,23561273;24055765;19209951 katG_promoter_size_107bp katG 299 GGC G A,C ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 297 GGC G V ISONIAZID 19209951 katG_promoter_size_107bp katG 295 CAG Q P ISONIAZID 19209951 katG_promoter_size_107bp katG 291 GCT A P ISONIAZID 19209951 katG_promoter_size_107bp katG 289 GAG E D ISONIAZID 19209951 katG_promoter_size_107bp katG 285 GGC G D ISONIAZID 19209951 katG_promoter_size_107bp katG 281 GCC A V ISONIAZID 19209951 katG_promoter_size_107bp katG 280 CCG P H ISONIAZID 24731071 katG_promoter_size_107bp katG 279 GGC G D ISONIAZID 19209951 katG_promoter_size_107bp katG 275 ACC T S,A,P ISONIAZID 19209951,19209951,24055765;10884617;19209951 katG_promoter_size_107bp katG 264 GCG A T ISONIAZID 19209951 katG_promoter_size_107bp katG 262 ACA T R ISONIAZID 10884617;19209951 katG_promoter_size_107bp katG 261 GAA E K ISONIAZID 23561273 katG_promoter_size_107bp katG 259 GAC D E ISONIAZID 23561273 katG_promoter_size_107bp katG 258 AAC N S ISONIAZID 19209951 katG_promoter_size_107bp katG 257 ATG M I,T ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 252 TTT F L ISONIAZID 19209951 katG_promoter_size_107bp katG 251 ACG T M ISONIAZID 19209951 katG_promoter_size_107bp katG 249 CGC R C ISONIAZID 19209951 katG_promoter_size_107bp katG 243 GCC A S ISONIAZID 19209951 katG_promoter_size_107bp katG 241 CCC P P ISONIAZID 19209951 katG_promoter_size_107bp katG 238 AAC N K ISONIAZID 19209951 katG_promoter_size_107bp katG 236 AAC N T ISONIAZID 19209951 katG_promoter_size_107bp katG 234 GGG G E,R ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 230 GTG V A ISONIAZID 19209951 katG_promoter_size_107bp katG 229 TAC Y F ISONIAZID 19209951 katG_promoter_size_107bp katG 224 CAG Q E ISONIAZID 19209951 katG_promoter_size_107bp katG 218 AAC N K ISONIAZID 19209951 katG_promoter_size_107bp katG 200 AAG K * ISONIAZID 19209951 katG_promoter_size_107bp katG 198 TGG W * ISONIAZID 19209951 katG_promoter_size_107bp katG 195 GAG E K ISONIAZID 19209951 katG_promoter_size_107bp katG 191 TGG W R ISONIAZID 19209951 katG_promoter_size_107bp katG 186 GGC G V,H ISONIAZID 19209951,24731071 katG_promoter_size_107bp katG 180 ACG T K ISONIAZID 19209951 katG_promoter_size_107bp katG 176 ATG M I ISONIAZID 19209951 katG_promoter_size_107bp katG 172 GCG A V,T ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 169 GGC G A ISONIAZID 19209951 katG_promoter_size_107bp katG 162 GCG A T ISONIAZID 19209951 katG_promoter_size_107bp katG 160 TCA S L ISONIAZID 19209951 katG_promoter_size_107bp katG 155 TAC Y C,S ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 148 CTG L R ISONIAZID 19209951 katG_promoter_size_107bp katG 143 AAG K T ISONIAZID 19209951 katG_promoter_size_107bp katG 142 GAC D A ISONIAZID 19209951 katG_promoter_size_107bp katG 141 TTG L F ISONIAZID 19209951 katG_promoter_size_107bp katG 140 AGC S R,N,G ISONIAZID 19209951,19209951,19209951 katG_promoter_size_107bp katG 139 GCC A P ISONIAZID 19209951 katG_promoter_size_107bp katG 138 AAC N S,T,D,H ISONIAZID 19209951,19209951,19209951,19209951 katG_promoter_size_107bp katG 128 CGG R P ISONIAZID 19209951 katG_promoter_size_107bp katG 127 CAG Q P ISONIAZID 19209951 katG_promoter_size_107bp katG 126 ATG M I ISONIAZID 19209951 katG_promoter_size_107bp katG 125 GGC G C ISONIAZID 19209951 katG_promoter_size_107bp katG 121 GGC G V,C ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 117 GAC D A ISONIAZID 19209951 katG_promoter_size_107bp katG 110 GCC A V ISONIAZID 19209951 katG_promoter_size_107bp katG 109 GCT A V ISONIAZID 19209951 katG_promoter_size_107bp katG 108 CAC H Q,E,D ISONIAZID 10884617;19209951,24731071,19209951 katG_promoter_size_107bp katG 107 TGG W *,R ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 106 GCG A V ISONIAZID 19209951 katG_promoter_size_107bp katG 104 CGG R L,Q ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 99 GGG G E ISONIAZID 19209951 katG_promoter_size_107bp katG 96 GGC G C ISONIAZID 19209951 katG_promoter_size_107bp katG 94 GAC D G,A ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 91 TGG W R ISONIAZID 19209951 katG_promoter_size_107bp katG 90 TGG W * ISONIAZID 19209951 katG_promoter_size_107bp katG 88 CAG Q R ISONIAZID 19209951 katG_promoter_size_107bp katG 85 ACC T P ISONIAZID 19209951 katG_promoter_size_107bp katG 84 ATG M I ISONIAZID 19209951 katG_promoter_size_107bp katG 74 GAC D G,Y ISONIAZID 19209951,19209951 katG_promoter_size_107bp katG 72 GAC D G ISONIAZID 19209951 katG_promoter_size_107bp katG 71 ATC I N ISONIAZID 19209951 katG_promoter_size_107bp katG 66 GCG A P ISONIAZID 19209951 katG_promoter_size_107bp katG 65 GCC A T ISONIAZID 19209951 katG_promoter_size_107bp katG 63 GAC D E ISONIAZID 10884617;19209951 katG_promoter_size_107bp katG 61 GCG A T ISONIAZID 19209951 katG_promoter_size_107bp katG 48 CTG L Q ISONIAZID 19209951 katG_promoter_size_107bp katG 38 TGG W * ISONIAZID 19209951 katG_promoter_size_107bp katG 35 AAC N D ISONIAZID 19209951 katG_promoter_size_107bp katG 19 GGC G D ISONIAZID 19209951 katG_promoter_size_107bp katG 17 AGC S N ISONIAZID 19209951 katG_promoter_size_107bp katG 12 ACC T P ISONIAZID 19209951 katG_promoter_size_107bp katG 11 ACC T A ISONIAZID 19209951 katG_promoter_size_107bp katG 2 CCC P S ISONIAZID 19209951 katG_promoter_size_107bp katG 1 GTG V A,L ISONIAZID 19209951,19209951 ahpC_promoter_size_180bp ahpC_promoter -81 C C T ISONIAZID 10884617 ahpC_promoter_size_180bp ahpC_promoter -74 G G A ISONIAZID 10884617;19209951 ahpC_promoter_size_180bp ahpC_promoter -66 G G A ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC_promoter -54 C C T ISONIAZID 10884617;19209951 ahpC_promoter_size_180bp ahpC_promoter -52 C C T ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC_promoter -51 G G T ISONIAZID 10884617 ahpC_promoter_size_180bp ahpC_promoter -49 T T G ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC_promoter -48 G G A,T ISONIAZID 19209951,23561273;10884617 ahpC_promoter_size_180bp ahpC_promoter -44 T T A ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC_promoter -39 C C T ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC_promoter -20 C C T ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC_promoter -5 G G A ISONIAZID 19209951 ahpC_promoter_size_180bp ahpC_promoter -4 A A G ISONIAZID 19209951 fabG1_promoter_size_223bp fabG1_promoter -92 A A T ISONIAZID 19209951 fabG1_promoter_size_223bp fabG1_promoter -67 G G C ISONIAZID 19209951 fabG1_promoter_size_223bp fabG1_promoter -24 G G T ISONIAZID 10884617;19209951 fabG1_promoter_size_223bp fabG1_promoter -16 A A G ISONIAZID Jin_et_al._2012;19209951 fabG1_promoter_size_223bp fabG1_promoter -11 A A T ISONIAZID 19209951 fabG1_promoter_size_223bp fabG1_promoter -8 T T A,C,G ISONIAZID 10884617;22461677;Jin_et_al._2012;19209951,23561273;19486070;Jin_et_al._2012;19209951,10884617;22461677;19209951 fabG1_promoter_size_223bp fabG1_promoter -5 T T A ISONIAZID 19209951 katG_promoter_size_107bp katG_promoter -7 G G A ISONIAZID 24055765 katG_promoter_size_107bp katG_promoter -10 A A C ISONIAZID 24055765 katG_promoter_size_107bp katG_promoter -12 G G A ISONIAZID 24055765 eis_promoter_size_119bp eis_promoter -8 C C A KANAMYCIN 23995137 eis_promoter_size_119bp eis_promoter -10 G G A,C KANAMYCIN 23995137;23288402;23705640;22461677;22479378,22479378 eis_promoter_size_119bp eis_promoter -12 C C T KANAMYCIN 23995137;23705640;22461677;22479378 eis_promoter_size_119bp eis_promoter -13 A A G KANAMYCIN 23705640 eis_promoter_size_119bp eis_promoter -14 C C T KANAMYCIN 23995137;23705640;22461677;22479378 eis_promoter_size_119bp eis_promoter -15 C C G KANAMYCIN 22461677;22479378 eis_promoter_size_119bp eis_promoter -37 G G T KANAMYCIN 23995137;23288402;23705640;22461677;22479378 eis_promoter_size_119bp eis_promoter -53 T T G KANAMYCIN 23995137 eis_promoter_size_119bp eis_promoter -54 G G T KANAMYCIN 23995137 rplC rplC 154 TGT C R LINEZOLID 22371899 rrl rrl 2299 G G T LINEZOLID 18070973 rrl rrl 2814 G G T LINEZOLID 18070973 thyA thyA 222 CGC R G Para-aminosalicyclic acid 19209951 thyA thyA 101 TGG W R Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 75 CAC H N Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 22 ACC T A Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 36 TAT Y C Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 76 GGA G * Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 77 GTC V F Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 83 TGG W C,* Para-aminosalicyclic acid Zhang_et_al._2014,Zhang_et_al._2014 thyA thyA 91 GGG G R Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 98 TGG W * Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 105 TCC S P Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 126 CGG R Q Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 152 TTC F V Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 161 TGT C Y Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 207 CAC H R Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 224 CCG P L Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 235 CGG R P Para-aminosalicyclic acid Zhang_et_al._2014 folC folC 153 GAG E G,A Para-aminosalicyclic acid 24366731;Zhang_et_al._2014,Zhang_et_al._2014 folC folC 152 TTC F S,L Para-aminosalicyclic acid 24366731,24366731 folC folC 150 AGC S R,G,C Para-aminosalicyclic acid 24366731,24366731;Zhang_et_al._2014,Zhang_et_al._2014 folC folC 73 AAC N S Para-aminosalicyclic acid 24366731 folC folC 40 GAG E G,Q Para-aminosalicyclic acid 24366731;Zhang_et_al._2014,Zhang_et_al._2014 folC folC 183 GCC A P Para-aminosalicyclic acid 24366731 folC folC 49 CGG R W,P Para-aminosalicyclic acid 24366731;Zhang_et_al._2014,Zhang_et_al._2014 folC folC 20 ACT T P Para-aminosalicyclic acid Zhang_et_al._2014 folC folC 43 ATC I T,S,A Para-aminosalicyclic acid 24366731;Zhang_et_al._2014,Zhang_et_al._2014,24366731;Zhang_et_al._2014 folC folC 56 CTG L V Para-aminosalicyclic acid Zhang_et_al._2014 folC folC 91 CGG R W Para-aminosalicyclic acid Zhang_et_al._2014 ribD ribD 8 GGA G R Para-aminosalicyclic acid Zhang_et_al._2014 pncA_promoter_size_107bp pncA 185 AGC S I,T PYRAZINAMIDE 19209951,19209951 pncA_promoter_size_107bp pncA 182 TTG L S PYRAZINAMIDE 23561273;22825123;19209951 pncA_promoter_size_107bp pncA 181 GAG E D PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 180 GTC V F PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 179 AGC S R PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 175 ATG M I,R,V PYRAZINAMIDE 22825123,24131688;23561273,22825123;17596354;19209951 pncA_promoter_size_107bp pncA 174 GAG E G PYRAZINAMIDE 24131688 pncA_promoter_size_107bp pncA 172 CTG L R,P,A PYRAZINAMIDE 22825123,22825123;19209951,24731071 pncA_promoter_size_107bp pncA 171 GCG A V,E,T,P PYRAZINAMIDE 19209951,22825123;19209951,19209951,19209951 pncA_promoter_size_107bp pncA 168 ACC T N,P PYRAZINAMIDE 19209951,24131688;23561273 pncA_promoter_size_107bp pncA 165 GCC A T PYRAZINAMIDE 19832709 pncA_promoter_size_107bp pncA 162 GGT G D PYRAZINAMIDE 24131688;19209951 pncA_promoter_size_107bp pncA 161 GCG A P PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 160 ACA T P PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 159 CTG L R,P PYRAZINAMIDE 24131688;23561273;19209951,22825123;19209951 pncA_promoter_size_107bp pncA 155 GTG V G,A,L PYRAZINAMIDE 22825123;19209951,23561273;19209951,23561273 pncA_promoter_size_107bp pncA 154 AGG R M,G PYRAZINAMIDE 22825123,19209951 pncA_promoter_size_107bp pncA 153 ACC T N PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 148 CGC R S PYRAZINAMIDE 17596354;19209951 pncA_promoter_size_107bp pncA 146 GCG A V,T PYRAZINAMIDE 19209951,23561273;22825123;19209951 pncA_promoter_size_107bp pncA 143 GCC A T,P PYRAZINAMIDE 22825123,22825123 pncA_promoter_size_107bp pncA 142 ACG T M,K,A,P PYRAZINAMIDE 23561273;22825123;19209951,22825123;19209951,19209951,19209951 pncA_promoter_size_107bp pncA 141 CAG Q P,* PYRAZINAMIDE 24131688;23561273;22825123;19209951,22825123;19209951 pncA_promoter_size_107bp pncA 140 CGC R H,S,G PYRAZINAMIDE 19832709,19209951,22825123 pncA_promoter_size_107bp pncA 139 GTG V G,A,L,M PYRAZINAMIDE 24131688;19209951,24131688;23561273;23995137;22825123;19209951,24131688;22825123;19209951,19209951 pncA_promoter_size_107bp pncA 138 TGT C *,Y,S PYRAZINAMIDE 23561273,19209951,19209951 pncA_promoter_size_107bp pncA 137 CAT H R,P PYRAZINAMIDE 19209951,19832709;19209951 pncA_promoter_size_107bp pncA 136 GAT D G,Y,N,H PYRAZINAMIDE 24131688;23561273;22825123;19209951,23995137;17596354;19209951,19209951,19209951 pncA_promoter_size_107bp pncA 135 ACC T P PYRAZINAMIDE 24131688;23561273;23995137;19209951 pncA_promoter_size_107bp pncA 134 GCC A V,S PYRAZINAMIDE 22825123;19209951,19832709 pncA_promoter_size_107bp pncA 133 ATT I N,T PYRAZINAMIDE 19209951,17596354;19209951 pncA_promoter_size_107bp pncA 132 GGT G V,D,A,S PYRAZINAMIDE 22825123,23561273;19209951,24131688,17596354;19209951 pncA_promoter_size_107bp pncA 131 GTC V F PYRAZINAMIDE 23561273 pncA_promoter_size_107bp pncA 130 GTG V G,A PYRAZINAMIDE 19209951,23561273 pncA_promoter_size_107bp pncA 128 GTC V G PYRAZINAMIDE 23995137;19209951 pncA_promoter_size_107bp pncA 125 GTC V D,G PYRAZINAMIDE 19209951,19209951 pncA_promoter_size_107bp pncA 121 CGG R P PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 120 CTG L P PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 119 TGG W C,*,R PYRAZINAMIDE 23561273;19209951,19209951,23995137;19209951 pncA_promoter_size_107bp pncA 118 AAT N T PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 116 CTG L R,P,V PYRAZINAMIDE 19209951,22825123,19209951 pncA_promoter_size_107bp pncA 114 ACG T A,P PYRAZINAMIDE 19832709,19209951 pncA_promoter_size_107bp pncA 108 GGA G R PYRAZINAMIDE 23561273 pncA_promoter_size_107bp pncA 107 GAA E * PYRAZINAMIDE 22825123 pncA_promoter_size_107bp pncA 104 AGC S R PYRAZINAMIDE 23561273;22825123;19209951 pncA_promoter_size_107bp pncA 103 TAC Y *,C,S,H PYRAZINAMIDE 22825123;19209951,19209951,19209951,22825123;19209951 pncA_promoter_size_107bp pncA 102 GCG A V,T PYRAZINAMIDE 23995137;19209951,19209951 pncA_promoter_size_107bp pncA 99 TAC Y * PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 97 GGT G D,S PYRAZINAMIDE 19209951,23561273;19209951 pncA_promoter_size_107bp pncA 96 AAG K N,T,E,Q PYRAZINAMIDE 19209951,23561273;19209951,24131688;23561273;19209951,19209951 pncA_promoter_size_107bp pncA 95 TAC Y * PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 94 TTC F L,S,P PYRAZINAMIDE 24131688,24131688,24731071 pncA_promoter_size_107bp pncA 90 ATC I S PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 88 TCG S * PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 87 ACG T M PYRAZINAMIDE 22825123;19209951 pncA_promoter_size_107bp pncA 85 CTG L R,P PYRAZINAMIDE 22825123;19209951,19209951 pncA_promoter_size_107bp pncA 82 CAT H L,R,Y,D PYRAZINAMIDE 19209951,24131688;23561273;22825123;19209951,19209951,22825123 pncA_promoter_size_107bp pncA 81 TTC F V PYRAZINAMIDE 24131688 pncA_promoter_size_107bp pncA 79 GCG A G PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 78 GGC G D,S PYRAZINAMIDE 19209951,19832709 pncA_promoter_size_107bp pncA 76 ACT T I,P PYRAZINAMIDE 19209951,24131688;23561273;22825123;19209951 pncA_promoter_size_107bp pncA 72 TGC C *,W,Y,R PYRAZINAMIDE 23561273,17596354;19209951,22825123;19209951,19209951 pncA_promoter_size_107bp pncA 71 CAT H R,Y,N,D PYRAZINAMIDE 19209951,22825123;19209951,22825123,19209951 pncA_promoter_size_107bp pncA 69 CCA P L,R PYRAZINAMIDE 19209951,23561273;19209951 pncA_promoter_size_107bp pncA 68 TGG W *,L,S,R,G PYRAZINAMIDE 23561273;19209951,19209951,19209951,22825123;19209951,19209951 pncA_promoter_size_107bp pncA 67 TCG S P PYRAZINAMIDE 22825123;19209951 pncA_promoter_size_107bp pncA 66 TCG S P PYRAZINAMIDE 24131688;19209951 pncA_promoter_size_107bp pncA 64 TAT Y D PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 63 GAC D G,A,H PYRAZINAMIDE 22825123;19209951,22825123,19209951 pncA_promoter_size_107bp pncA 62 CCG P L,R PYRAZINAMIDE 23561273;19209951,19209951 pncA_promoter_size_107bp pncA 61 ACA T P PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 59 TCC S P PYRAZINAMIDE 23561273;23995137;22825123;19832709;19209951 pncA_promoter_size_107bp pncA 58 TTC F L,S PYRAZINAMIDE 23561273;23995137;19209951,24131688 pncA_promoter_size_107bp pncA 57 CAC H L,R,P,Y,N,D PYRAZINAMIDE 19209951,22825123,19209951,24131688;19209951,22825123,19209951 pncA_promoter_size_107bp pncA 54 CCG P L,Q,T PYRAZINAMIDE 24131688;17596354;19832709;19209951,23561273;22825123,19209951 pncA_promoter_size_107bp pncA 53 GAC D A,N PYRAZINAMIDE 19209951,17596354;19209951 pncA_promoter_size_107bp pncA 51 CAC H Q,R,P,Y,N PYRAZINAMIDE 17596354;19832709;19209951,22825123;19209951,23561273;19209951,22825123;19209951,19209951 pncA_promoter_size_107bp pncA 49 GAC D V,G,A,N,H PYRAZINAMIDE 19209951,23561273;19209951,23561273;22825123;19209951,23561273;22825123,19209951 pncA_promoter_size_107bp pncA 47 ACC T S,A,P PYRAZINAMIDE 19209951,24131688;23995137;19209951,23561273;19209951 pncA_promoter_size_107bp pncA 46 GCA A V,E,P PYRAZINAMIDE 23561273;22825123;19209951,19209951,19209951 pncA_promoter_size_107bp pncA 45 GTG V G PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 44 GTC V G PYRAZINAMIDE 23995137 pncA_promoter_size_107bp pncA 43 CAC H P PYRAZINAMIDE 22825123;19209951 pncA_promoter_size_107bp pncA 41 TAC Y *,H PYRAZINAMIDE 19209951,19209951 pncA_promoter_size_107bp pncA 37 GAA E * PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 35 CTG L R,P PYRAZINAMIDE 19209951,22825123;19209951 pncA_promoter_size_107bp pncA 34 TAC Y *,S,D PYRAZINAMIDE 22825123,19209951,19832709 pncA_promoter_size_107bp pncA 31 ATC I S PYRAZINAMIDE 22825123 pncA_promoter_size_107bp pncA 28 GCC A D PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 27 CTG L P PYRAZINAMIDE 17596354 pncA_promoter_size_107bp pncA 26 GCG A G PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 25 GCC A E PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 24 GGC G D,R PYRAZINAMIDE 24131688;22825123,22825123 pncA_promoter_size_107bp pncA 23 GGT G V PYRAZINAMIDE 19209951;24731071 pncA_promoter_size_107bp pncA 21 GTA V G PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 19 CTG L R,P PYRAZINAMIDE 19209951,19209951 pncA_promoter_size_107bp pncA 18 TCG S P PYRAZINAMIDE 24131688 pncA_promoter_size_107bp pncA 17 GGC G V,D PYRAZINAMIDE 19209951,19209951 pncA_promoter_size_107bp pncA 14 TGC C *,W,Y,G,R PYRAZINAMIDE 22825123,23561273,19209951,23561273,19209951 pncA_promoter_size_107bp pncA 13 TTC F L,S PYRAZINAMIDE 24131688;22825123,19209951 pncA_promoter_size_107bp pncA 12 GAC D A,N PYRAZINAMIDE 23561273;22825123;17596354;19209951,22825123;19209951 pncA_promoter_size_107bp pncA 10 CAG Q R,P,*,K PYRAZINAMIDE 19209951,24131688;22825123;17596354;19209951;24731071,23561273;22825123;19209951,19209951 pncA_promoter_size_107bp pncA 9 GTG V G,A,L,S PYRAZINAMIDE 22825123;19832709;19209951,19209951,19209951,24731071 pncA_promoter_size_107bp pncA 8 GAC D E,G,A,Y,N PYRAZINAMIDE 19209951,23561273;19209951,24131688;22825123,22825123;19209951,22825123 pncA_promoter_size_107bp pncA 7 GTC V D,G,F,I PYRAZINAMIDE 19209951,19209951,19209951,19209951 #pncA_promoter_size_107bp pncA 6 ATC I S,L PYRAZINAMIDE 23561273,23561273;23995137 pncA_promoter_size_107bp pncA 6 ATC I S PYRAZINAMIDE 23561273 pncA_promoter_size_107bp pncA 5 ATC I S PYRAZINAMIDE 19209951 pncA_promoter_size_107bp pncA 4 TTG L W,S PYRAZINAMIDE 19209951,19209951 pncA_promoter_size_107bp pncA 3 GCG A E,P PYRAZINAMIDE 19209951,19209951 pncA_promoter_size_107bp pncA 1 ATG M I,T PYRAZINAMIDE 22825123;19209951,22825123;19209951 rpsA rpsA 433 GAG E D PYRAZINAMIDE 24131688 rpsA rpsA 474 CGG R W,L PYRAZINAMIDE 24131688,24131688 panD panD 128 GCG A S PYRAZINAMIDE 26038471 panD panD 138 GTG V A,G,E,A PYRAZINAMIDE 26038471,26038753,26038753,26038753 panD panD 49 ATC I V PYRAZINAMIDE 26038471 panD panD 21 CAC H R PYRAZINAMIDE 26038471 panD panD 130 GAG E G PYRAZINAMIDE 26038471 panD panD 117 ATG M I PYRAZINAMIDE 26038753 panD panD 136 CTC L R PYRAZINAMIDE 26038753 panD panD 126 GAA E * PYRAZINAMIDE 26038753 pncA_promoter_size_107bp pncA_promoter -7 T T C PYRAZINAMIDE 22825123;19832709;19209951 pncA_promoter_size_107bp pncA_promoter -10 T T C PYRAZINAMIDE 22825123 pncA_promoter_size_107bp pncA_promoter -11 A A G,C PYRAZINAMIDE 24131688;22825123;19209951,19209951 pncA_promoter_size_107bp pncA_promoter -12 T T G,C PYRAZINAMIDE 19209951,22825123 rpoB rpoB 170 GTC V F RIFAMPICIN 24731071 rpoB rpoB 286 GCG A V RIFAMPICIN 24731071 rpoB rpoB 400 ACC T A RIFAMPICIN 23561273 rpoB rpoB 409 CAG Q H RIFAMPICIN 19209951 rpoB rpoB 423 GAG E A RIFAMPICIN 19209951 rpoB rpoB 424 TTC F L,V,S RIFAMPICIN 19209951,23561273,19209951 rpoB rpoB 426 GGC G S,D RIFAMPICIN 19209951,19209951;24731071 rpoB rpoB 427 ACC T S,P,A,H RIFAMPICIN 19209951,19209951,19209951,24731071 rpoB rpoB 428 AGC S R,Q,I,T RIFAMPICIN 23561273;19209951,24731071,23561273,22461677;19209951 rpoB rpoB 429 CAG Q K,H RIFAMPICIN 19209951,24055765;22461677;19864480;19209951 rpoB rpoB 430 CTG L V,P,R RIFAMPICIN 19209951,23561273;23995137;Shi_et_al._2013;22461677;19864480;19209951,Shi_et_al._2013;22461677;19864480;19209951 rpoB rpoB 431 AGC S R,G,I,T RIFAMPICIN 19209951,23995137;19209951,24055765;19209951,19209951 rpoB rpoB 432 CAA Q N,K,*,E,L,P,R,H RIFAMPICIN 24731071,19864480;19209951,19209951,19209951,23561273;24055765;19864480;19209951,23561273;22461677;19864480;19209951,19209951,19209951 rpoB rpoB 433 TTC F L,V RIFAMPICIN 19209951,19209951 rpoB rpoB 434 ATG M T,I RIFAMPICIN 23561273,23561273;24055765;19209951 rpoB rpoB 435 GAC D F,N,Y,H,V,A,G,E RIFAMPICIN 24731071,19209951,24055765;Wang_et_al._2013;22461677;19864480;19209951,19209951,23561273;23995137;24055765;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;Jin_et_al._2012;19209951;24731071,,19209951,24055765;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;19209951,19209951 rpoB rpoB 436 CAG Q L,H RIFAMPICIN 19209951,19209951 rpoB rpoB 437 AAC N Y,H,D,I,T RIFAMPICIN 19209951,19209951,19209951,19209951,19209951 rpoB rpoB 438 AAC N K RIFAMPICIN 19209951 rpoB rpoB 440 CTG L M,L,P RIFAMPICIN 19209951,19209951,19209951 rpoB rpoB 441 TCG S Q,L,W RIFAMPICIN 24731071,23561273;19864480;19209951,19864480;19209951 rpoB rpoB 442 GGG G W,A RIFAMPICIN 19209951,19209951 rpoB rpoB 443 TTG L S,W RIFAMPICIN 19209951,19209951 rpoB rpoB 444 ACC T P,I RIFAMPICIN 19209951,19209951 #rpoB rpoB 445 CAC H F,G,N,Y,D,L,P,R,Q RIFAMPICIN 24731071,24731071,23995137;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;19209951,23561273;24055765;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;Jin_et_al._2012;19209951,24055765;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;Jin_et_al._2012;19209951,24731071;23561273;22461677;19864480;19209951,19864480;19209951,Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;19209951,23561273;23995137;19209951 rpoB rpoB 445 CAC H F,G,Y,D,L,P,R,Q RIFAMPICIN 24731071,24731071,23561273;24055765;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;Jin_et_al._2012;19209951,24055765;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;Jin_et_al._2012;19209951,24731071;23561273;22461677;19864480;19209951,19864480;19209951,Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;19209951,23561273;23995137;19209951 rpoB rpoB 446 AAG K Q,N RIFAMPICIN 19209951,19209951 rpoB rpoB 447 CGC R P,H RIFAMPICIN 24731071;19209951,19209951 rpoB rpoB 450 TCG S Q,L,W,F,Y RIFAMPICIN 24731071,23561273;23995137;24055765;Shi_et_al._2013;Wang_et_al._2013;22461677;19864480;Jin_et_al._2012;19209951,22461677;19864480;19209951,24731071,24731071 rpoB rpoB 452 CTG L P RIFAMPICIN 24731071;23561273;22461677;19864480;19209951 rpoB rpoB 454 CCC P S,H,L,R RIFAMPICIN 19209951,19209951,23561273;22461677,22461677 rpoB rpoB 457 CTG L P RIFAMPICIN 19209951 rpoB rpoB 460 GAG E G RIFAMPICIN 19209951 rpoB rpoB 464 CTG L M RIFAMPICIN 19209951 rpoB rpoB 472 TCG S A RIFAMPICIN 19209951 rpoB rpoB 480 ATC I V,T RIFAMPICIN 23995137;19209951,19209951 rpoB rpoB 481 GAA E G RIFAMPICIN 19209951 rpoB rpoB 482 ACC T P RIFAMPICIN 23561273 rpoB rpoB 483 CCT P L RIFAMPICIN 19209951 rpoB rpoB 490 CTG L V RIFAMPICIN 19209951 rpoB rpoB 491 ATC I F RIFAMPICIN 24055765;19209951 rpoB rpoB 493 TCG S L RIFAMPICIN 19209951 rpoB rpoB 552 CGC R C RIFAMPICIN 19209951 rpoB rpoB 592 GAG E D RIFAMPICIN 24731071 rpoB rpoB 761 GAG E D RIFAMPICIN 23995137 rpoC rpoC 332 GGC G R RIFAMPICIN 23995137 rpoC rpoC 452 TTC F S RIFAMPICIN 23995137 rpoC rpoC 485 GAT D N RIFAMPICIN 23995137 rpoC rpoC 491 ATC I T RIFAMPICIN 23995137 rpoC rpoC 527 TTG L V RIFAMPICIN 23995137 rpoC rpoC 735 GAC D N RIFAMPICIN 23995137 rpoC rpoC 747 GAC D A RIFAMPICIN 23995137 rpoC rpoC 885 ATC I V RIFAMPICIN 23995137 rpsL rpsL 9 CGC R H STREPTOMYCIN 19209951 rpsL rpsL 40 ACC T I STREPTOMYCIN 19209951 rpsL rpsL 41 ACT T S STREPTOMYCIN 19209951 rpsL rpsL 43 AAG K T,R STREPTOMYCIN 19209951,23561273;23906937;19209951 rpsL rpsL 51 AAG K N STREPTOMYCIN 19209951 rpsL rpsL 52 GTT V G STREPTOMYCIN 19209951 rpsL rpsL 84 GGC G V STREPTOMYCIN 19209951 rpsL rpsL 86 CGG R W,P STREPTOMYCIN 19209951,19209951 rpsL rpsL 87 GTG V L STREPTOMYCIN 19209951 rpsL rpsL 88 AAG K Q,M,T,R STREPTOMYCIN 23906937;19209951,19209951,23906937;19209951,23561273;23906937;19209951 rpsL rpsL 93 GTG V M STREPTOMYCIN 19209951 rrs rrs 190 G G A STREPTOMYCIN 19209951 rrs rrs 277 G G C STREPTOMYCIN 23561273;23906937 rrs rrs 427 G G T,C STREPTOMYCIN 19209951,19209951 rrs rrs 462 C C T STREPTOMYCIN 19209951 #rrs rrs 492 C C T STREPTOMYCIN 19209951 rrs rrs 513 C C T STREPTOMYCIN 19209951 rrs rrs 514 A A T,C STREPTOMYCIN 19209951,23561273;19209951 rrs rrs 516 C C T STREPTOMYCIN 23906937 rrs rrs 628 G G C STREPTOMYCIN 19209951 rrs rrs 799 C C T STREPTOMYCIN 19209951 rrs rrs 888 G G A STREPTOMYCIN 19209951 rrs rrs 905 C C A,G STREPTOMYCIN 19209951,19209951 rrs rrs 906 A A G STREPTOMYCIN 19209951 rrs rrs 907 A A T,C STREPTOMYCIN 23561273;23906937;19209951,19209951 rrs rrs 908 A A G STREPTOMYCIN 19209951 rrs rrs 1229 C C T STREPTOMYCIN 23561273;23906937 rrs rrs 1239 T T C STREPTOMYCIN 19209951 rrs rrs 1402 C C T STREPTOMYCIN 23906937 #Stop codons katG_promoter_size_107bp katG 1 N N * ISONIAZID - ethA_promoter_size_74bp ethA 1 N N * ETHIONAMIDE - pncA_promoter_size_107bp pncA 1 N N * PYRAZINAMIDE - gidB gidB 1 N N * STREPTOMYCIN - #New mutations with high frequency in GWAS study, PMID:29358649 iniA iniA 42 CAC H R d-cycloserine 29358649 alr alr 113 CTG L R D-CYCLOSERINE 29358649 ubiA ubiA 188 GTG V A ETHAMBUTOL 29358649 ubiA ubiA 249 GCG A T ETHAMBUTOL 29358649 gidB gidB 79 TTG L S STREPTOMYCIN 29358649 gidB gidB 80 GCG A P STREPTOMYCIN 29358649 gidB gidB 149 AGC S R STREPTOMYCIN 29358649 idsA2_promoter_size_181bp idsA2_promoter -65 A A G CAPREOMYCIN 29358649 thyX_promoter_size_259bp thyX_promoter -16 C C T Para-aminosalicyclic acid 29358649 ethA_promoter_size_74bp ethA_promoter -65 T T C ETHIONAMIDE 29358649 #nuoA_promoter_size_365bp nuoA_promoter 1 -314 G G T XDR-TB 29358649 nuoA_promoter_size_365bp nuoA_promoter -314 G G T XDR-TB 29358649 rpoB rpoB 731 CTG L P RIFAMPICIN 29358649 rpoC rpoC 416 AAC N S RIFAMPICIN 29358649 rpoC rpoC 483 GTG V A RIFAMPICIN 29358649 rpoC rpoC 483 GTG V G RIFAMPICIN 29358649 rpoC rpoC 484 TGG W G RIFAMPICIN 29358649 rpoC rpoC 491 ATC I V RIFAMPICIN 29358649 rpoC rpoC 516 CTG L P RIFAMPICIN 29358649 rpoC rpoC 698 AAC N S RIFAMPICIN 29358649 rpoC rpoC 1040 CCG P S RIFAMPICIN 29358649 rpoC rpoC 1040 CCG P R RIFAMPICIN 29358649 rpoC rpoC 1152 AAG K Q RIFAMPICIN 29358649 rpoC rpoC 1252 GTG V L RIFAMPICIN 29358649 rrs rrs 513 C C T STREPTOMYCIN 29358649 rrs rrs 514 A A T STREPTOMYCIN 29358649 #pncA_promoter_size_107bp pncA 1 151 TTG L S PYRAZINAMIDE 29358649 pncA_promoter_size_107bp pncA 151 TTG L S PYRAZINAMIDE 29358649 #embB embB 1 423 ATG M T ETHAMBUTOL 29358649 embB embB 423 ATG M T ETHAMBUTOL 29358649 #ahpC_promoter_size_180bp ahpC_promoter 1 -72 C C T ISONIAZID 29358649 ahpC_promoter_size_180bp ahpC_promoter -72 C C T ISONIAZID 29358649 #embA_promoter_size_115bp embA_promoter 1 -8 C C T ETHAMBUTOL 29358649 embA_promoter_size_115bp embA_promoter -8 C C T ETHAMBUTOL 29358649 #embA_promoter_size_115bp embA_promoter 1 -12 C C A ETHAMBUTOL 29358649 embA_promoter_size_115bp embA_promoter -12 C C A ETHAMBUTOL 29358649 #embA_promoter_size_115bp embA_promoter 1 -16 C C G ETHAMBUTOL 29358649 embA_promoter_size_115bp embA_promoter -16 C C G ETHAMBUTOL 29358649 #embA_promoter_size_115bp embA_promoter 1 -43 G G C ETHAMBUTOL 29358649 embA_promoter_size_115bp embA_promoter -43 G G C ETHAMBUTOL 29358649 #drrA drrA 1 262 AGG R G XDR-TB 29358649 drrA drrA 262 AGG R G XDR-TB 29358649 #Indels #Gene_id Gene_name Nuc_pos - Mut_type Insert/deletion Drug Pmid tlyA tlyA 23 - del A CAPREOMYCIN 19209951 tlyA tlyA 26 - del C CAPREOMYCIN 19209951 tlyA tlyA 67 - del GCC CAPREOMYCIN 19209951 tlyA tlyA 310 - del G CAPREOMYCIN 19209951 tlyA tlyA 400 - del A CAPREOMYCIN 19209951 tlyA tlyA 477 - del G CAPREOMYCIN 19209951 tlyA tlyA 586 - del G CAPREOMYCIN 19209951 tlyA tlyA 653 - del T CAPREOMYCIN 19209951 tlyA tlyA 673 - del GT CAPREOMYCIN 19209951 tlyA tlyA 758 - del C CAPREOMYCIN 19209951 embB embB 983 - del A ETHAMBUTOL 19209951 ethA_promoter_size_74bp ethA 1322 - del GC ETHIONAMIDE 19209951 ethA_promoter_size_74bp ethA 1290 - del C ETHIONAMIDE 19209951 ethA_promoter_size_74bp ethA 768 - del G ETHIONAMIDE 19209951 ethA_promoter_size_74bp ethA 703 - del T ETHIONAMIDE 19209951 ethA_promoter_size_74bp ethA 110 - del A ETHIONAMIDE 19209951 katG_promoter_size_107bp katG 2203 - del GAC ISONIAZID 24731071;19209951 katG_promoter_size_107bp katG 1667 - del C ISONIAZID 24731071;19209951 katG_promoter_size_107bp katG 1203 - del C ISONIAZID 24731071 katG_promoter_size_107bp katG 1091 - del T ISONIAZID 24731071;19209951 katG_promoter_size_107bp katG 1037 - del G ISONIAZID 24731071 katG_promoter_size_107bp katG 928 - del A ISONIAZID 24731071;19209951 katG_promoter_size_107bp katG 803 - del G ISONIAZID 24731071 katG_promoter_size_107bp katG 795 - del G ISONIAZID 19209951 katG_promoter_size_107bp katG 572 - del G ISONIAZID 24731071;19209951 katG_promoter_size_107bp katG 561 - del G ISONIAZID 19209951 katG_promoter_size_107bp katG 358 - del GGCGGCGCCGGG ISONIAZID 24731071 katG_promoter_size_107bp katG 152 - del ACCCGGCCGTCGCTG ISONIAZID 24731071 katG_promoter_size_107bp katG 149 - del A ISONIAZID 24731071;19209951 katG_promoter_size_107bp katG 109 - del G ISONIAZID 24731071;19209951 katG_promoter_size_107bp katG 28 - del GAAACCAC ISONIAZID 24731071 katG_promoter_size_107bp katG 1850 - ins AC ISONIAZID 24731071 katG_promoter_size_107bp katG 1560 - ins TGCAGCCACAAGTCGGGTGGGAGGTCAACGACCCCGACGGGGATCTGCGCAAGGTCATTCGCAC ISONIAZID 24731071 katG_promoter_size_107bp katG 1330 - ins A ISONIAZID 24731071 katG_promoter_size_107bp katG 1171 - ins CTA ISONIAZID 24731071 katG_promoter_size_107bp katG 902 - ins T ISONIAZID 24731071 katG_promoter_size_107bp katG 374 - ins CAT ISONIAZID 24731071 katG_promoter_size_107bp katG 373 - ins G ISONIAZID 24731071 katG_promoter_size_107bp katG 196 - ins CCCC ISONIAZID 24731071 katG_promoter_size_107bp katG 186 - ins C ISONIAZID 24731071 katG_promoter_size_107bp katG 99 - ins A ISONIAZID 24731071 thyA thyA 86 - del C Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 111 - del T Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 472 - del C Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 218 - ins CACGAGCAC Para-aminosalicyclic acid Zhang_et_al._2014 thyA thyA 373 - ins T Para-aminosalicyclic acid Zhang_et_al._2014 pncA_promoter_size_107bp pncA 512 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 475 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 446 - del ATGGCTTG PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 452 - del T PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 443 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 436 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 416 - del TG PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 406 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 395 - del GTATTGCCACC PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 391 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 379 - del GAGGTCGATGT PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 386 - del ATGT PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 381 - del GG PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 341 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 312 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 307 - del TACAG PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 288 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 239 - del A PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 172 - del T PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 162 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 161 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 158 - del A PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 118 - del GACTACCATCACGTCGTGGCAACCAAGGACTTC PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 88 - del GCCATCAGCGACTACCTGGCCGAA PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 84 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 71 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 70 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 64 - del A PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 59 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 47 - del G PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 28 - del C PYRAZINAMIDE 24731071;19209951 pncA_promoter_size_107bp pncA 1 - del ATGCGGGCGTT,ATGCGGGC PYRAZINAMIDE 24731071,24731071 pncA_promoter_size_107bp pncA 533 - ins C PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 519 - ins NNNNN PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 502 - ins GC PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 481 - ins TGAC PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 466 - ins T PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 429 - ins GG PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 421 - ins GG,G PYRAZINAMIDE 24731071,24731071 pncA_promoter_size_107bp pncA 415 - ins G PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 408 - ins C PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 404 - ins C PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 398 - ins T PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 393 - ins G PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 392 - ins GG PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 389 - ins GAGGTCGAT,AGGTCGATG PYRAZINAMIDE 24731071,24731071 pncA_promoter_size_107bp pncA 383 - ins AG PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 369 - ins NNNNNNNNNNNNNNNNNN,AG PYRAZINAMIDE 24731071,24731071 pncA_promoter_size_107bp pncA 307 - ins C PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 302 - ins G,A PYRAZINAMIDE 24731071,24731071 pncA_promoter_size_107bp pncA 288 - ins T PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 222 - ins G PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 219 - ins CGCATTGCCG PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 193 - ins A PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 163 - ins T PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 137 - ins G PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 101 - ins T PYRAZINAMIDE 24731071 pncA_promoter_size_107bp pncA 53 - ins GG PYRAZINAMIDE 24731071 panD panD 393 - del G PYRAZINAMIDE 26038753 rpoB rpoB 1275 - del CGGCAC RIFAMPICIN 24731071 rpoB rpoB 1276 - del GGCACC RIFAMPICIN 24731071;19209951 rpoB rpoB 1294 - del CAATTC RIFAMPICIN 24731071;19209951 rpoB rpoB 1295 - del AATTCATGG RIFAMPICIN 24731071;19209951 rpoB rpoB 1297 - del TTCATGGAC,TTC RIFAMPICIN 19209951;24731071,19209951 rpoB rpoB 1299 - del CAT,CATGGACCAGAA RIFAMPICIN 24731071;19209951,24731071 rpoB rpoB 1300 - del ATGGACCAGAAC RIFAMPICIN 19209951;24731071 rpoB rpoB 1303 - del GACCAG RIFAMPICIN 24731071;19209951 rpoB rpoB 1306 - del CAGAAC,CAG RIFAMPICIN 24731071;19209951,24731071 rpoB rpoB 1308 - del GAACAA RIFAMPICIN 24731071;19209951 rpoB rpoB 1312 - del AAC RIFAMPICIN 24731071;19209951 rpoB rpoB 1336 - del AAG RIFAMPICIN 19209951;24731071 rpoB rpoB 1294 - ins TTCATG,TTC RIFAMPICIN 24731071,24731071 rpoB rpoB 1297 - ins CGG RIFAMPICIN 24731071 rpoB rpoB 1300 - ins TTC RIFAMPICIN 24731071 Rv0678 Rv0678 193 - ins G BEDAQUILINE,CLOFAZIMINE 25010492 Rv0678 Rv0678 39 - ins A BEDAQUILINE,CLOFAZIMINE 25010492