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1 <?xml version="1.0"?>
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2 <!DOCTYPE BlastOutput PUBLIC "-//NCBI//NCBI BlastOutput/EN" "NCBI_BlastOutput.dtd">
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3 <BlastOutput>
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4 <BlastOutput_program>blastp</BlastOutput_program>
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5 <BlastOutput_version>BLASTP 2.2.24+</BlastOutput_version>
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6 <BlastOutput_reference>Stephen F. Altschul, Thomas L. Madden, Alejandro A. Sch&auml;ffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402.</BlastOutput_reference>
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7 <BlastOutput_db>/data/blastdb/pdbaa</BlastOutput_db>
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8 <BlastOutput_query-ID>Query_1</BlastOutput_query-ID>
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9 <BlastOutput_query-def>sp|Q9BS26|ERP44_HUMAN Endoplasmic reticulum resident protein 44 OS=Homo sapiens GN=ERP44 PE=1 SV=1</BlastOutput_query-def>
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10 <BlastOutput_query-len>406</BlastOutput_query-len>
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11 <BlastOutput_param>
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12 <Parameters>
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13 <Parameters_matrix>BLOSUM62</Parameters_matrix>
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14 <Parameters_expect>1e-08</Parameters_expect>
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15 <Parameters_gap-open>11</Parameters_gap-open>
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16 <Parameters_gap-extend>1</Parameters_gap-extend>
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17 <Parameters_filter>F</Parameters_filter>
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18 </Parameters>
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19 </BlastOutput_param>
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20 <BlastOutput_iterations>
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21 <Iteration>
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22 <Iteration_iter-num>1</Iteration_iter-num>
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23 <Iteration_query-ID>Query_1</Iteration_query-ID>
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24 <Iteration_query-def>sp|Q9BS26|ERP44_HUMAN Endoplasmic reticulum resident protein 44 OS=Homo sapiens GN=ERP44 PE=1 SV=1</Iteration_query-def>
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25 <Iteration_query-len>406</Iteration_query-len>
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26 <Iteration_hits>
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27 <Hit>
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28 <Hit_num>1</Hit_num>
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29 <Hit_id>gi|193885198|pdb|2R2J|A</Hit_id>
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30 <Hit_def>Chain A, Crystal Structure Of Human Erp44</Hit_def>
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31 <Hit_accession>2R2J_A</Hit_accession>
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32 <Hit_len>382</Hit_len>
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33 <Hit_hsps>
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34 <Hsp>
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35 <Hsp_num>1</Hsp_num>
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36 <Hsp_bit-score>768.073791748238</Hsp_bit-score>
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37 <Hsp_score>1982</Hsp_score>
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38 <Hsp_evalue>0</Hsp_evalue>
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39 <Hsp_query-from>26</Hsp_query-from>
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40 <Hsp_query-to>406</Hsp_query-to>
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41 <Hsp_hit-from>2</Hsp_hit-from>
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42 <Hsp_hit-to>382</Hsp_hit-to>
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43 <Hsp_query-frame>0</Hsp_query-frame>
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44 <Hsp_hit-frame>0</Hsp_hit-frame>
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45 <Hsp_identity>370</Hsp_identity>
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46 <Hsp_positive>372</Hsp_positive>
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47 <Hsp_gaps>0</Hsp_gaps>
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48 <Hsp_align-len>381</Hsp_align-len>
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49 <Hsp_qseq>PVTTEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDMVYLGAMTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHMYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL</Hsp_qseq>
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50 <Hsp_hseq>PLGSEITSLDTENIDEILNNADVALVNFYADWCRFSQXLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGXXXKREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPDXVYLGAXTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHXKEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRHXYVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL</Hsp_hseq>
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51 <Hsp_midline>P+ +EITSLDTENIDEILNNADVALVNFYADWCRFSQ LHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNG KREYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNIIYKPPGHSAPD VYLGA TNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFH KEDTESLEIFQNEVARQLISEKGTINFLHADCDKFRHPLLHIQKTPADCPVIAIDSFRH YVFGDFKDVLIPGKLKQFVFDLHSGKLHREFHHGPDPTDTAPGEQAQDVASSPPESSFQKLAPSEYRYTLLRDRDEL</Hsp_midline>
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52 </Hsp>
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53 </Hit_hsps>
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54 </Hit>
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55 <Hit>
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56 <Hit_num>2</Hit_num>
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57 <Hit_id>gi|88192228|pdb|2B5E|A</Hit_id>
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58 <Hit_def>Chain A, Crystal Structure Of Yeast Protein Disulfide Isomerase >gi|206581884|pdb|3BOA|A Chain A, Crystal Structure Of Yeast Protein Disulfide Isomerase.</Hit_def>
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59 <Hit_accession>2B5E_A</Hit_accession>
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60 <Hit_len>504</Hit_len>
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61 <Hit_hsps>
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62 <Hsp>
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63 <Hsp_num>1</Hsp_num>
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64 <Hsp_bit-score>95.130132620622</Hsp_bit-score>
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65 <Hsp_score>235</Hsp_score>
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66 <Hsp_evalue>4.15033135540548e-20</Hsp_evalue>
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67 <Hsp_query-from>25</Hsp_query-from>
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68 <Hsp_query-to>306</Hsp_query-to>
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69 <Hsp_hit-from>10</Hsp_hit-from>
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70 <Hsp_hit-to>283</Hsp_hit-to>
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71 <Hsp_query-frame>0</Hsp_query-frame>
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72 <Hsp_hit-frame>0</Hsp_hit-frame>
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73 <Hsp_identity>73</Hsp_identity>
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74 <Hsp_positive>133</Hsp_positive>
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75 <Hsp_gaps>24</Hsp_gaps>
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76 <Hsp_align-len>290</Hsp_align-len>
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77 <Hsp_qseq>TPVTTEITSLDTENIDEILNNADVALVNFYADWCRFSQMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKR-EYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNIIGYFEQKDSDNYRVFERVANILHDDCAFLSAFGDVSKPERYSGDNI---IYKPPGHSAPDMVYLGA---MTNFDVTYNWIQDKCVPLVREITFENGEELTEEGLPFLILFHMKEDTESLEIFQNEVARQLISEKGTINFLHADCDKF-RH</Hsp_qseq>
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78 <Hsp_hseq>APEDSAVVKLATDSFNEYIQSHDLVLAEFFAPWCGHCKNMAPEYVKAAETLVEK-----NITLAQIDCTENQDLCMEHNIPGFPSLKIFKNSDVNNSIDYEGPRTAEAIVQFMIKQSQPAVAVVADLPAYLANETFVTPVIVQSGKIDADFNATFYSMANKHFNDYDFVSA--------ENADDDFKLSIYLPSAMDEP-VVYNGKKADIADADVFEKWLQVEALPYFGEIDGSVFAQYVESGLPLGYLFY--NDEEELEEYKPLFTELAKKNRGLMNFVSIDARKFGRH</Hsp_hseq>
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79 <Hsp_midline> P + + L T++ +E + + D+ L F+A WC + + P + +A++ + E+ + A++DC ++ D+ + I +P+LK+F+N + +Y G R+ +A+ ++ +Q + + DL + +I + D+D F +AN +D F+SA + D+ IY P P +VY G + + DV W+Q + +P EI + E GLP LF+ D E LE ++ +G +NF+ D KF RH</Hsp_midline>
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80 </Hsp>
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81 </Hit_hsps>
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82 </Hit>
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83 </Iteration_hits>
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84 <Iteration_stat>
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85 <Statistics>
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86 <Statistics_db-num>49615</Statistics_db-num>
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87 <Statistics_db-len>11554246</Statistics_db-len>
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88 <Statistics_hsp-len>0</Statistics_hsp-len>
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89 <Statistics_eff-space>2039204827</Statistics_eff-space>
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90 <Statistics_kappa>0.041</Statistics_kappa>
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91 <Statistics_lambda>0.267</Statistics_lambda>
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92 <Statistics_entropy>0.14</Statistics_entropy>
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93 </Statistics>
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94 </Iteration_stat>
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95 </Iteration>
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96 <Iteration>
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97 <Iteration_iter-num>2</Iteration_iter-num>
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98 <Iteration_query-ID>Query_2</Iteration_query-ID>
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99 <Iteration_query-def>sp|Q9NSY1|BMP2K_HUMAN BMP-2-inducible protein kinase OS=Homo sapiens GN=BMP2K PE=1 SV=2</Iteration_query-def>
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100 <Iteration_query-len>1161</Iteration_query-len>
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101 <Iteration_hits>
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102 <Hit>
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103 <Hit_num>1</Hit_num>
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104 <Hit_id>gi|73536291|pdb|2BUJ|A</Hit_id>
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105 <Hit_def>Chain A, Crystal Structure Of The Human Serine-Threonine Kinase 16 In Complex With Staurosporine >gi|73536292|pdb|2BUJ|B Chain B, Crystal Structure Of The Human Serine-Threonine Kinase 16 In Complex With Staurosporine</Hit_def>
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106 <Hit_accession>2BUJ_A</Hit_accession>
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107 <Hit_len>317</Hit_len>
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108 <Hit_hsps>
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109 <Hsp>
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110 <Hsp_num>1</Hsp_num>
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111 <Hsp_bit-score>105.530521170391</Hsp_bit-score>
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112 <Hsp_score>262</Hsp_score>
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113 <Hsp_evalue>1.04156432658542e-22</Hsp_evalue>
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114 <Hsp_query-from>40</Hsp_query-from>
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115 <Hsp_query-to>308</Hsp_query-to>
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116 <Hsp_hit-from>21</Hsp_hit-from>
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117 <Hsp_hit-to>294</Hsp_hit-to>
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118 <Hsp_query-frame>0</Hsp_query-frame>
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119 <Hsp_hit-frame>0</Hsp_hit-frame>
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120 <Hsp_identity>82</Hsp_identity>
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121 <Hsp_positive>130</Hsp_positive>
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122 <Hsp_gaps>15</Hsp_gaps>
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123 <Hsp_align-len>279</Hsp_align-len>
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124 <Hsp_qseq>GVRVFAVGRHQVTLEESLAEGGFSTVFLVR-THGGIRCALKRMYVNNMPDLNVCKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMNKKLQTG--FTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDG-VNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPF------GESQVAICDGNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDI</Hsp_qseq>
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125 <Hsp_hseq>GHMVIIDNKHYLFIQK-LGEGGFSYVDLVEGLHDGHFYALKRILCHEQQDREEAQREAD-MHRLFNHPNILRLVAYCLRERGAKH-EAWLLLPFFKRGTLWNEIERLKDKGNFLTEDQILWLLLGICRGLEAIH--AKGYAHRDLKPTNILLGDEGQPVLMDLGSMNQACIHVEGSRQALTLQDWAAQRCTISYRAPELFSVQSHCVIDERTDVWSLGCVLYAMMFGEGPYDMVFQKGDSVALAVQNQLSIPQSPRHSSALWQLLNSMMTVDPHQRPHI</Hsp_hseq>
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126 <Hsp_midline>G V +H + +++ L EGGFS V LV H G ALKR+ + D +RE M L H NI+ + + E +L+ + + G + N++ + G TE ++L + C + +H HRDLK NILL D G VL D GS ++ + +++ + T+SYRAPE+ ++ I + D+W+LGC+LY + F P+ G+S +IP + R+S + L+ M+ DP RP I</Hsp_midline>
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127 </Hsp>
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128 </Hit_hsps>
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129 </Hit>
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130 <Hit>
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131 <Hit_num>2</Hit_num>
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132 <Hit_id>gi|270346335|pdb|2WQM|A</Hit_id>
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133 <Hit_def>Chain A, Structure Of Apo Human Nek7 >gi|270346336|pdb|2WQN|A Chain A, Structure Of Adp-Bound Human Nek7</Hit_def>
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134 <Hit_accession>2WQM_A</Hit_accession>
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135 <Hit_len>310</Hit_len>
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136 <Hit_hsps>
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137 <Hsp>
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138 <Hsp_num>1</Hsp_num>
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139 <Hsp_bit-score>86.2705423745229</Hsp_bit-score>
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140 <Hsp_score>212</Hsp_score>
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141 <Hsp_evalue>6.48475818195287e-17</Hsp_evalue>
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142 <Hsp_query-from>53</Hsp_query-from>
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143 <Hsp_query-to>311</Hsp_query-to>
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144 <Hsp_hit-from>36</Hsp_hit-from>
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145 <Hsp_hit-to>288</Hsp_hit-to>
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146 <Hsp_query-frame>0</Hsp_query-frame>
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147 <Hsp_hit-frame>0</Hsp_hit-frame>
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148 <Hsp_identity>74</Hsp_identity>
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149 <Hsp_positive>129</Hsp_positive>
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150 <Hsp_gaps>32</Hsp_gaps>
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151 <Hsp_align-len>272</Hsp_align-len>
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152 <Hsp_qseq>LEESLAEGGFSTVFLVRTH-GGIRCALKRMYVNNMPDLNV---CKREITIMKELSGHKNIVGYLDCAVNSISDNVWEVLILMEYCRAGQVVNQMN--KKLQTGFTEPEVLQIFCDTCEAVARLHQCKTPIIHRDLKVENILLNDGGNYVLCDFGSATNKFLNPQKDGVNVVEEEIKKYTTLSYRAPEMINLYGGKPITTKADIWALGCLLYKLCFFTLPFGESQV---AICD----GNFTIPDNSRYSRNIHCLIRFMLEPDPEHRPDIFQV</Hsp_qseq>
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153 <Hsp_hseq>IEKKIGRGQFSEVYRAACLLDGVPVALKKVQIFDLMDAKARADCIKEIDLLKQLN-HPNVIKYY---ASFIEDN--ELNIVLELADAGDLSRMIKHFKKQKRLIPERTVWKYFVQLCSALEHMHSRR--VMHRDIKPANVFITATGVVKLGDLG--LGRFFSSKTTAAHSL------VGTPYYMSPERIHENG---YNFKSDIWSLGCLLYEMAALQSPFYGDKMNLYSLCKKIEQCDYPPLPSDHYSEELRQLVNMCINPDPEKRPDVTYV</Hsp_hseq>
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154 <Hsp_midline>+E+ + G FS V+ G+ ALK++ + ++ D C +EI ++K+L+ H N++ Y + I DN E+ I++E AG + + KK + E V + F C A+ +H + ++HRD+K N+ + G L D G +F + + + + T Y +PE I+ G K+DIW+LGCLLY++ PF ++ ++C ++ + YS + L+ + PDPE RPD+ V</Hsp_midline>
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155 </Hsp>
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156 </Hit_hsps>
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157 </Hit>
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158 </Iteration_hits>
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159 <Iteration_stat>
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160 <Statistics>
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161 <Statistics_db-num>49615</Statistics_db-num>
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162 <Statistics_db-len>11554246</Statistics_db-len>
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163 <Statistics_hsp-len>0</Statistics_hsp-len>
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164 <Statistics_eff-space>6524204778</Statistics_eff-space>
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165 <Statistics_kappa>0.041</Statistics_kappa>
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166 <Statistics_lambda>0.267</Statistics_lambda>
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167 <Statistics_entropy>0.14</Statistics_entropy>
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168 </Statistics>
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169 </Iteration_stat>
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170 </Iteration>
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171 <Iteration>
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172 <Iteration_iter-num>3</Iteration_iter-num>
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173 <Iteration_query-ID>Query_3</Iteration_query-ID>
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174 <Iteration_query-def>sp|P06213|INSR_HUMAN Insulin receptor OS=Homo sapiens GN=INSR PE=1 SV=4</Iteration_query-def>
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175 <Iteration_query-len>1382</Iteration_query-len>
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176 <Iteration_hits>
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177 <Hit>
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178 <Hit_num>1</Hit_num>
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179 <Hit_id>gi|116667097|pdb|2DTG|E</Hit_id>
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180 <Hit_def>Chain E, Insulin Receptor (Ir) Ectodomain In Complex With Fab's</Hit_def>
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181 <Hit_accession>2DTG_E</Hit_accession>
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182 <Hit_len>897</Hit_len>
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183 <Hit_hsps>
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184 <Hsp>
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185 <Hsp_num>1</Hsp_num>
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186 <Hsp_bit-score>1846.24740474091</Hsp_bit-score>
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187 <Hsp_score>4781</Hsp_score>
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188 <Hsp_evalue>0</Hsp_evalue>
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189 <Hsp_query-from>28</Hsp_query-from>
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190 <Hsp_query-to>955</Hsp_query-to>
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191 <Hsp_hit-from>1</Hsp_hit-from>
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192 <Hsp_hit-to>897</Hsp_hit-to>
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193 <Hsp_query-frame>0</Hsp_query-frame>
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194 <Hsp_hit-frame>0</Hsp_hit-frame>
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195 <Hsp_identity>890</Hsp_identity>
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196 <Hsp_positive>893</Hsp_positive>
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197 <Hsp_gaps>31</Hsp_gaps>
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198 <Hsp_align-len>928</Hsp_align-len>
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199 <Hsp_qseq>HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIA</Hsp_qseq>
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200 <Hsp_hseq>HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFV------------PRPSRKRRSLGDVGNA-------------------GNNEEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCDTRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIA</Hsp_hseq>
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201 <Hsp_midline>HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDN+IVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWERQAEDSELFELDYCLKGLKLPSRTWSPPFESEDSQKHNQSEYEDSAGECCSCPKTDSQILKELEESSFRKTFEDYLHNVVFV PRPSRKRRSLGDVGN + EEHRPFEKVVNKESLVISGLRHFTGYRIELQACNQDTPEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLC +RKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTDYLDVPSNIA</Hsp_midline>
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202 </Hsp>
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203 </Hit_hsps>
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204 </Hit>
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205 <Hit>
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|
206 <Hit_num>2</Hit_num>
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207 <Hit_id>gi|114794482|pdb|2HR7|A</Hit_id>
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208 <Hit_def>Chain A, Insulin Receptor (Domains 1-3) >gi|114794483|pdb|2HR7|B Chain B, Insulin Receptor (Domains 1-3)</Hit_def>
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209 <Hit_accession>2HR7_A</Hit_accession>
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210 <Hit_len>486</Hit_len>
|
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211 <Hit_hsps>
|
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|
212 <Hsp>
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|
213 <Hsp_num>1</Hsp_num>
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|
214 <Hsp_bit-score>1016.91271779085</Hsp_bit-score>
|
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|
215 <Hsp_score>2628</Hsp_score>
|
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216 <Hsp_evalue>0</Hsp_evalue>
|
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|
217 <Hsp_query-from>28</Hsp_query-from>
|
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|
218 <Hsp_query-to>512</Hsp_query-to>
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|
219 <Hsp_hit-from>1</Hsp_hit-from>
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220 <Hsp_hit-to>485</Hsp_hit-to>
|
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|
221 <Hsp_query-frame>0</Hsp_query-frame>
|
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|
222 <Hsp_hit-frame>0</Hsp_hit-frame>
|
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|
223 <Hsp_identity>483</Hsp_identity>
|
|
|
224 <Hsp_positive>485</Hsp_positive>
|
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|
225 <Hsp_gaps>0</Hsp_gaps>
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|
226 <Hsp_align-len>485</Hsp_align-len>
|
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|
227 <Hsp_qseq>HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCENELLKFSYIRTSFDKI</Hsp_qseq>
|
|
|
228 <Hsp_hseq>HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNHIVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDKASCENELLKFSYIRTSFDKI</Hsp_hseq>
|
|
|
229 <Hsp_midline>HLYPGEVCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDN+IVLNKDDNEECGDICPGTAKGKTNCPATVINGQFVERCWTHSHCQKVCPTICKSHGCTAEGLCCHSECLGNCSQPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCQDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPCLGPCPKVCHLLEGEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGD+ASCENELLKFSYIRTSFDKI</Hsp_midline>
|
|
|
230 </Hsp>
|
|
|
231 </Hit_hsps>
|
|
|
232 </Hit>
|
|
|
233 </Iteration_hits>
|
|
|
234 <Iteration_stat>
|
|
|
235 <Statistics>
|
|
|
236 <Statistics_db-num>49615</Statistics_db-num>
|
|
|
237 <Statistics_db-len>11554246</Statistics_db-len>
|
|
|
238 <Statistics_hsp-len>0</Statistics_hsp-len>
|
|
|
239 <Statistics_eff-space>7824126603</Statistics_eff-space>
|
|
|
240 <Statistics_kappa>0.041</Statistics_kappa>
|
|
|
241 <Statistics_lambda>0.267</Statistics_lambda>
|
|
|
242 <Statistics_entropy>0.14</Statistics_entropy>
|
|
|
243 </Statistics>
|
|
|
244 </Iteration_stat>
|
|
|
245 </Iteration>
|
|
|
246 <Iteration>
|
|
|
247 <Iteration_iter-num>4</Iteration_iter-num>
|
|
|
248 <Iteration_query-ID>Query_4</Iteration_query-ID>
|
|
|
249 <Iteration_query-def>sp|P08100|OPSD_HUMAN Rhodopsin OS=Homo sapiens GN=RHO PE=1 SV=1</Iteration_query-def>
|
|
|
250 <Iteration_query-len>348</Iteration_query-len>
|
|
|
251 <Iteration_hits>
|
|
|
252 <Hit>
|
|
|
253 <Hit_num>1</Hit_num>
|
|
|
254 <Hit_id>gi|16975387|pdb|1JFP|A</Hit_id>
|
|
|
255 <Hit_def>Chain A, Structure Of Bovine Rhodopsin (Dark Adapted) >gi|22219255|pdb|1LN6|A Chain A, Structure Of Bovine Rhodopsin (Metarhodopsin Ii) >gi|157878065|pdb|1GZM|A Chain A, Structure Of Bovine Rhodopsin In A Trigonal Crystal Form >gi|157878066|pdb|1GZM|B Chain B, Structure Of Bovine Rhodopsin In A Trigonal Crystal Form >gi|157878298|pdb|1HZX|A Chain A, Crystal Structure Of Bovine Rhodopsin >gi|157878299|pdb|1HZX|B Chain B, Crystal Structure Of Bovine Rhodopsin >gi|157878979|pdb|1L9H|A Chain A, Crystal Structure Of Bovine Rhodopsin At 2.6 Angstroms Resolution >gi|157878980|pdb|1L9H|B Chain B, Crystal Structure Of Bovine Rhodopsin At 2.6 Angstroms Resolution >gi|157880263|pdb|1U19|A Chain A, Crystal Structure Of Bovine Rhodopsin At 2.2 Angstroms Resolution >gi|157880264|pdb|1U19|B Chain B, Crystal Structure Of Bovine Rhodopsin At 2.2 Angstroms Resolution >gi|157883606|pdb|2G87|A Chain A, Crystallographic Model Of Bathorhodopsin >gi|157883607|pdb|2G87|B Chain B, Crystallographic Model Of Bathorhodopsin >gi|157883830|pdb|2HPY|A Chain A, Crystallographic Model Of Lumirhodopsin >gi|157883831|pdb|2HPY|B Chain B, Crystallographic Model Of Lumirhodopsin >gi|157883860|pdb|2I35|A Chain A, Crystal Structure Of Rhombohedral Crystal Form Of Ground- State Rhodopsin >gi|157883861|pdb|2I36|A Chain A, Crystal Structure Of Trigonal Crystal Form Of Ground-State Rhodopsin >gi|157883862|pdb|2I36|B Chain B, Crystal Structure Of Trigonal Crystal Form Of Ground-State Rhodopsin >gi|157883863|pdb|2I36|C Chain C, Crystal Structure Of Trigonal Crystal Form Of Ground-State Rhodopsin >gi|157883864|pdb|2I37|A Chain A, Crystal Structure Of A Photoactivated Rhodopsin >gi|157883865|pdb|2I37|B Chain B, Crystal Structure Of A Photoactivated Rhodopsin >gi|157883866|pdb|2I37|C Chain C, Crystal Structure Of A Photoactivated Rhodopsin >gi|159795066|pdb|2PED|A Chain A, Crystallographic Model Of 9-Cis-Rhodopsin >gi|159795067|pdb|2PED|B Chain B, Crystallographic Model Of 9-Cis-Rhodopsin >gi|192988480|pdb|3CAP|A Chain A, Crystal Structure Of Native Opsin: The G Protein-Coupled Receptor Rhodopsin In Its Ligand-Free State >gi|192988481|pdb|3CAP|B Chain B, Crystal Structure Of Native Opsin: The G Protein-Coupled Receptor Rhodopsin In Its Ligand-Free State >gi|195927457|pdb|3C9L|A Chain A, Structure Of Ground-State Bovine Rhodospin In A Hexagonal Crystal Form >gi|197107530|pdb|1F88|A Chain A, Crystal Structure Of Bovine Rhodopsin >gi|197107531|pdb|1F88|B Chain B, Crystal Structure Of Bovine Rhodopsin >gi|206582030|pdb|3DQB|A Chain A, Crystal Structure Of The Active G-Protein-Coupled Receptor Opsin In Complex With A C-Terminal Peptide Derived From The Galpha Subunit Of Transducin</Hit_def>
|
|
|
256 <Hit_accession>1JFP_A</Hit_accession>
|
|
|
257 <Hit_len>348</Hit_len>
|
|
|
258 <Hit_hsps>
|
|
|
259 <Hsp>
|
|
|
260 <Hsp_num>1</Hsp_num>
|
|
|
261 <Hsp_bit-score>681.018687590916</Hsp_bit-score>
|
|
|
262 <Hsp_score>1756</Hsp_score>
|
|
|
263 <Hsp_evalue>0</Hsp_evalue>
|
|
|
264 <Hsp_query-from>1</Hsp_query-from>
|
|
|
265 <Hsp_query-to>348</Hsp_query-to>
|
|
|
266 <Hsp_hit-from>1</Hsp_hit-from>
|
|
|
267 <Hsp_hit-to>348</Hsp_hit-to>
|
|
|
268 <Hsp_query-frame>0</Hsp_query-frame>
|
|
|
269 <Hsp_hit-frame>0</Hsp_hit-frame>
|
|
|
270 <Hsp_identity>325</Hsp_identity>
|
|
|
271 <Hsp_positive>337</Hsp_positive>
|
|
|
272 <Hsp_gaps>0</Hsp_gaps>
|
|
|
273 <Hsp_align-len>348</Hsp_align-len>
|
|
|
274 <Hsp_qseq>MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVAPA</Hsp_qseq>
|
|
|
275 <Hsp_hseq>MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA</Hsp_hseq>
|
|
|
276 <Hsp_midline>MNGTEGPNFYVPFSN TGVVRSPFE PQYYLAEPWQFSMLAAYMFLLI+LGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMV GGFT+TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPL GWSRYIPEG+QCSCGIDYYT E NNESFVIYMFVVHF IP+I+IFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICW+PYA VAFYIFTHQGS+FGPIFMTIPAFFAK++A+YNPVIYIMMNKQFRNCM+TT+CCGKNPLGDDEAS TVSKTETSQVAPA</Hsp_midline>
|
|
|
277 </Hsp>
|
|
|
278 </Hit_hsps>
|
|
|
279 </Hit>
|
|
|
280 <Hit>
|
|
|
281 <Hit_num>2</Hit_num>
|
|
|
282 <Hit_id>gi|195927458|pdb|3C9M|A</Hit_id>
|
|
|
283 <Hit_def>Chain A, Structure Of A Mutant Bovine Rhodopsin In Hexagonal Crystal Form</Hit_def>
|
|
|
284 <Hit_accession>3C9M_A</Hit_accession>
|
|
|
285 <Hit_len>348</Hit_len>
|
|
|
286 <Hit_hsps>
|
|
|
287 <Hsp>
|
|
|
288 <Hsp_num>1</Hsp_num>
|
|
|
289 <Hsp_bit-score>674.085095224404</Hsp_bit-score>
|
|
|
290 <Hsp_score>1738</Hsp_score>
|
|
|
291 <Hsp_evalue>0</Hsp_evalue>
|
|
|
292 <Hsp_query-from>1</Hsp_query-from>
|
|
|
293 <Hsp_query-to>348</Hsp_query-to>
|
|
|
294 <Hsp_hit-from>1</Hsp_hit-from>
|
|
|
295 <Hsp_hit-to>348</Hsp_hit-to>
|
|
|
296 <Hsp_query-frame>0</Hsp_query-frame>
|
|
|
297 <Hsp_hit-frame>0</Hsp_hit-frame>
|
|
|
298 <Hsp_identity>324</Hsp_identity>
|
|
|
299 <Hsp_positive>335</Hsp_positive>
|
|
|
300 <Hsp_gaps>0</Hsp_gaps>
|
|
|
301 <Hsp_align-len>348</Hsp_align-len>
|
|
|
302 <Hsp_qseq>MNGTEGPNFYVPFSNATGVVRSPFEYPQYYLAEPWQFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVLGGFTSTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLAGWSRYIPEGLQCSCGIDYYTLKPEVNNESFVIYMFVVHFTIPMIIIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWVPYASVAFYIFTHQGSNFGPIFMTIPAFFAKSAAIYNPVIYIMMNKQFRNCMLTTICCGKNPLGDDEASATVSKTETSQVAPA</Hsp_qseq>
|
|
|
303 <Hsp_hseq>MCGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPLVGWSRYIPEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICWLPYAGVAFYIFTHQGSCFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRNCMVTTLCCGKNPLGDDEASTTVSKTETSQVAPA</Hsp_hseq>
|
|
|
304 <Hsp_midline>M GTEGPNFYVPFSN TGVVRSPFE PQYYLAEPWQFSMLAAYMFLLI+LGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADLFMV GGFT+TLYTSLHGYFVFGPTGCNLEGFFATLGGEIALWSLVVLAIERYVVVCKPMSNFRFGENHAIMGVAFTWVMALACAAPPL GWSRYIPEG+QCSCGIDYYT E NNESFVIYMFVVHF IP+I+IFFCYGQLVFTVKEAAAQQQESATTQKAEKEVTRMVIIMVIAFLICW+PYA VAFYIFTHQGS FGPIFMTIPAFFAK++A+YNPVIYIMMNKQFRNCM+TT+CCGKNPLGDDEAS TVSKTETSQVAPA</Hsp_midline>
|
|
|
305 </Hsp>
|
|
|
306 </Hit_hsps>
|
|
|
307 </Hit>
|
|
|
308 </Iteration_hits>
|
|
|
309 <Iteration_stat>
|
|
|
310 <Statistics>
|
|
|
311 <Statistics_db-num>49615</Statistics_db-num>
|
|
|
312 <Statistics_db-len>11554246</Statistics_db-len>
|
|
|
313 <Statistics_hsp-len>0</Statistics_hsp-len>
|
|
|
314 <Statistics_eff-space>1672994000</Statistics_eff-space>
|
|
|
315 <Statistics_kappa>0.041</Statistics_kappa>
|
|
|
316 <Statistics_lambda>0.267</Statistics_lambda>
|
|
|
317 <Statistics_entropy>0.14</Statistics_entropy>
|
|
|
318 </Statistics>
|
|
|
319 </Iteration_stat>
|
|
|
320 </Iteration>
|
|
|
321 </BlastOutput_iterations>
|
|
|
322 </BlastOutput>
|
