annotate w4mcorcov.xml @ 14:90708fdbc22d draft default tip

"planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 5fd9687d543a48a715b1180caf93abebebd58b0e"
author eschen42
date Wed, 18 Nov 2020 18:53:37 +0000
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1 <tool id="w4mcorcov" name="OPLS-DA_Contrasts" version="0.98.18">
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2 <description>OPLS-DA Contrasts of Univariate Results</description>
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3 <macros>
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4 <xml name="paramPairSigFeatOnly">
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5 <param name="pairSigFeatOnly" type="boolean" checked="true" truevalue="TRUE" falsevalue="FALSE"
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6 label="Retain only pairwise-significant features"
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7 help="When this option is set to 'Yes', analysis will be performed including only features scored by the univariate test as differing significantly for the pair of levels being contrasted; when set to 'No', any feature that varies significantly across all levels will be included (i.e., exclude only features not scored by the univariate test as significantly varying when all levels are considered). See examples below." />
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8 </xml>
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9 <xml name="cplots">
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10 <param name="cplot_y" label="C-plot Y-axis" type="select" help="Choose the Y-axis for C-plots.">
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11 <option value="correlation">Plot VIP versus correlation</option>
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12 <option value="covariance">Plot VIP versus covariance</option>
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13 </param>
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14 <param name="cplot_p" type="boolean" checked="true" truevalue="TRUE" falsevalue="FALSE"
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15 label="Produce predictor C-plot"
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16 help="When this option is set to 'Yes', correlation will be plotted against vip4 for predictor loadings." />
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17 <param name="cplot_o" type="boolean" checked="true" truevalue="TRUE" falsevalue="FALSE"
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18 label="Produce orthogonal C-plot"
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19 help="When this option is set to 'Yes', correlation will be plotted against vip4 for orthogonal loadings." />
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20 <param name="fdr_features" type="text" value="ALL"
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21 label="How many features for p-value calculation?"
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22 help="Specify how many features should be used to perform family-wise error rate adjustment of p-values for covariance and correlation. If you were to eliminate features from the data matrix based on significance criteria prior to running this tool, you would want to include them in the count here to avoid underestimating the p-value. Specify 'ALL' to signify that all features that could impact p-value calculation are included in the data matrix."/>
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23 </xml>
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24 </macros>
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25 <requirements>
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26 <requirement type="package">r-base</requirement>
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27 <requirement type="package">r-batch</requirement>
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28 <requirement type="package" version="1.22.0">bioconductor-ropls</requirement>
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29 </requirements>
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30 <command detect_errors="aggressive"><![CDATA[
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31 Rscript '$__tool_directory__/w4mcorcov_wrapper.R'
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32 dataMatrix_in '$dataMatrix_in'
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33 sampleMetadata_in '$sampleMetadata_in'
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34 variableMetadata_in '$variableMetadata_in'
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35 facC '$facC'
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36 #if str( $signif_test.tesC ) == 'none':
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37 tesC 'none'
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38 pairSigFeatOnly 'FALSE'
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39 #else:
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40 tesC '$signif_test.tesC'
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41 pairSigFeatOnly '$signif_test.pairSigFeatOnly'
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42 #end if
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43 levCSV '$levCSV'
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44 matchingC '$matchingC'
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45 labelFeatures '$labelFeatures'
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46 #if str( $advanced.advancedFeatures ) == 'none':
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47 fdr_features 'ALL'
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48 cplot_p 'FALSE'
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49 cplot_o 'FALSE'
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50 cplot_y 'correlation'
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51 #else if str( $advanced.advancedFeatures ) == 'advanced':
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52 fdr_features '$advanced.fdr_features'
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53 cplot_p '$advanced.cplot_p'
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54 cplot_o '$advanced.cplot_o'
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55 cplot_y '$advanced.cplot_y'
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56 #end if
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57 contrast_detail '$contrast_detail'
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58 contrast_corcov '$contrast_corcov'
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59 contrast_salience '$contrast_salience'
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60 min_crossval_i '$min_crossval_i'
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61 ]]></command>
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62 <inputs>
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63 <param name="dataMatrix_in" format="tabular" label="Data matrix file" type="data"
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64 help="variables &#10006; samples" />
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65 <param name="sampleMetadata_in" format="tabular" label="Sample metadata file" type="data"
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66 help="sample metadata, one row per sample" />
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67 <param name="variableMetadata_in" format="tabular" label="Variable metadata file (ideally from Univariate)"
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68 type="data" help="variable metadata, one row per variable" />
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69 <param name="facC" type="text"
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70 label="Factor of interest"
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71 help="REQUIRED - The name of the column of sampleMetadata corresponding to the qualitative variable used to define the contrasts. Except when the 'Univariate Significance-test' is set to 'none', this also must be a portion of the column names in the variableMetadata file.">
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72 <sanitizer>
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73 <valid initial="string.letters">
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74 <add preset="string.digits"/>
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75 <add value="&#46;" /> <!-- dot, period -->
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76 <add value="&#95;" /> <!-- underscore -->
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77 <!-- R does not permit dashes in column names; neither does SQL -->
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78 </valid>
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79 </sanitizer>
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80 </param>
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81 <conditional name="signif_test">
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82 <param name="tesC" label="Univariate significance-test" type="select" help="Either 'none' or the name of the statistical test that was run by the 'Univariate' tool to produce the variableMetadata file.">
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83 <option value="none">none - Display all features from variableMetadata (rather than choosing a subset based on significance in univariate testing)</option>
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84 <option value="ttest">ttest - Student's t-test (parametric test, qualitative factor with exactly 2 levels)</option>
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85 <option value="anova">anova - Analysis of variance (parametric test, qualitative factor with more than 2 levels)</option>
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86 <option value="wilcoxon">wilcoxon - Wilcoxon rank test (nonparametric test, qualitative factor with exactly 2 levels)</option>
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87 <option value="kruskal">kruskal - Kruskal-Wallis rank test (nonparametric test, qualitative factor with more than 2 levels)</option>
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88 </param>
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89 <when value="none" />
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90 <when value="ttest">
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91 <expand macro="paramPairSigFeatOnly" />
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92 </when>
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93 <when value="anova">
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94 <expand macro="paramPairSigFeatOnly" />
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95 </when>
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96 <when value="wilcoxon">
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97 <expand macro="paramPairSigFeatOnly" />
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98 </when>
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99 <when value="kruskal">
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100 <expand macro="paramPairSigFeatOnly" />
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101 </when>
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102 </conditional>
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103 <param name="levCSV" type="text" value="*" label="Levels of interest"
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104 help="Comma-separated level-names (or comma-separated regular expressions to match level-names) to consider in analysis; must match at least two levels; levels must be non-numeric; may include wild cards or regular expressions. Note that extra space characters will affect results - when 'a,b' is correct, 'a, b' is not equivalent and likely will fail or give different results.">
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105 <sanitizer>
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106 <valid initial="string.letters">
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107 <add preset="string.digits"/>
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108 <add value="&#36;" /> <!-- $ dollar, dollar-sign -->
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109 <add value="&#40;" /> <!-- ( left-paren -->
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110 <add value="&#41;" /> <!-- ) right-paren -->
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111 <add value="&#42;" /> <!-- * splat, asterisk -->
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112 <add value="&#43;" /> <!-- + plus -->
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113 <add value="&#44;" /> <!-- , comma -->
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114 <add value="&#45;" /> <!-- - dash, minus-sign -->
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115 <add value="&#46;" /> <!-- . dot, period -->
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116 <add value="&#58;" /> <!-- : colon -->
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117 <add value="&#59;" /> <!-- ; semi, semicolon -->
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118 <add value="&#63;" /> <!-- ? what, question mark -->
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119 <add value="&#91;" /> <!-- [ l-squib, left-squre-bracket -->
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120 <add value="&#92;" /> <!-- \ whack, backslash -->
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121 <add value="&#93;" /> <!-- ] r-squib, right-squre-bracket -->
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122 <add value="&#94;" /> <!-- ^ hat, caret -->
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123 <add value="&#95;" /> <!-- underscore -->
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124 <add value="&#123;" /> <!-- { l-cube, left-curly-bracket -->
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125 <add value="&#124;" /> <!-- | pipe -->
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126 <add value="&#125;" /> <!-- } r-cube, right-curly-bracket -->
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127 <!-- IMPORTANT - Note that single and double quotes are not part of this list; they have the potential to make the 'command' section insecure or broken. -->
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128 </valid>
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129 </sanitizer>
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130 </param>
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131 <param name="matchingC" label="Level-name matching" type="select" help="How to specify level-names generically. (See help below for details on using wild cards or regular expressions.)">
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132 <option value="none">do no generic matching</option>
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133 <option value="wildcard" selected="true">use wild-cards for matching level-names (default)</option>
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134 <option value="regex">use regular expressions for matching level-names</option>
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135 </param>
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136 <param name="labelFeatures" type="text" value="3"
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137 label="How many features having extreme loadings should be labelled on cov-vs.-cor plot?"
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138 help="Specify the number of features at each of the loading-extremes that should be labelled (with the name of the feature) on the covariance-vs.-correlation plot; specify 'ALL' to label all features or '0' to label no features; this choice has no effect on the OPLS-DA loadings plot."/>
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139 <param name="min_crossval_i" type="text" value="7"
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140 label="Minumum number of samples for OPLS-DA cross-validation."
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141 help="What is the minimum number of samples to be used by the ropls package for cross-validation of OPLS-DA predictions? This should be not more than half the number of your samples."/>
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142 <conditional name="advanced">
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143 <param name="advancedFeatures" type="select"
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144 label="Advanced (C-plots and customized p-value adjustment)"
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145 help="Choose 'Do not include ...' to hides further choices.">
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146 <option value="advanced">Include C-plots and customize p-value adjustment.</option>
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147 <option value="none">Do not include additonal C-plots or customize p-value adjustment.</option>
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148 </param>
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149 <when value="none" />
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150 <when value="advanced">
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151 <expand macro="cplots" />
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152 </when>
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153 </conditional>
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154 </inputs>
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155 <outputs>
0
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156 <!--
2
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157 pdf1: summaries of each contrasts, clearly labelled by level=pair name
0
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158 * first PCA score-plot
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159 * then OPLS score-plot
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160 * then OPLS S-PLOT; color saturation increases with VIP
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161 * then C-plots if requrested
0
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162 -->
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163 <data name="contrast_detail" format="pdf" label="${tool.name}_${variableMetadata_in.name}_detail" />
0
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164 <!--
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165 tsv1: cor and cov table with columns:
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166 * feature-ID
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167 * factor-level 1
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168 * factor-level 2, lexically greater than level 1
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169 * Wiklund_2008 correlation
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170 * Wiklund_2008 covariance
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171 * Galindo_Prieto_2014 VIP for predictive components, VIP[4,p]
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172 * Galindo_Prieto_2014 VIP for orthogonal components, VIP[4,o]
9
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173 * When filtering on significance of univariate tests,significance of test of null hypothesis that there is no difference between the two classes, i.e, the pair-wise test.
0
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174 -->
8
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175 <data name="contrast_corcov" format="tabular" label="${tool.name}_${variableMetadata_in.name}_corcov" />
0
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176 <!--
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177 tsv2: salience table with columns (experimental feature):
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178 * feature-ID
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179 * Salient level, i.e., for the feature, the class-level having the greatest median intensity
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180 * Salient robust coefficient of variation, i.e., for the feature, the mean absolute deviation of the intensity for the salient level divided by the median intensity for the salient level
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181 * Salience, i.e., for the feature, the median of the class-level having the greatest intensity divided by the mean of the medians for all class-levels.
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182 -->
8
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183 <data name="contrast_salience" format="tabular" label="${tool.name}_${variableMetadata_in.name}_salience" />
0
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184 </outputs>
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185 <tests>
14
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186 <!-- test #1 - issue 14 -->
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187 <test>
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188 <param name="dataMatrix_in" value="issue14_input_dataMatrix.tsv"/>
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189 <param name="sampleMetadata_in" value="issue14_input_sampleMetadata.tsv"/>
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190 <param name="variableMetadata_in" value="issue14_input_variableMetadata.tsv"/>
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191 <param name="tesC" value="none"/>
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192 <param name="facC" value="tissue_flowering"/>
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193 <param name="labelFeatures" value="3"/>
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194 <param name="min_crossval_i" value="4"/>
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195 <param name="fdr_features" value="ALL"/>
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196 <param name="levCSV" value="*"/>
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197 <param name="matchingC" value="wildcard"/>
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198 <output name="contrast_corcov">
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199 <assert_contents>
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200 <!-- column-labels line -->
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201 <has_text text="featureID" />
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202 <has_text text="factorLevel1" />
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203 <has_text text="factorLevel2" />
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204 <has_text text="correlation" />
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205 <has_text text="covariance" />
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206 <has_text text="vip4p" />
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207 <has_text text="vip4o" />
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208 <!-- a matched line -->
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209 <has_text text="NM516T283_1" />
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210 <has_text text="flower_yes" />
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211 <has_text text="leaf_no" />
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212 <has_text text="-0.98475578586" />
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213 <has_text text="-58.1219648" />
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214 <has_text text="2.0103501" />
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215 <has_text text="2.872672881" />
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216 <has_text text="-0.1208407903" />
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217 <has_text text="-0.2032249" />
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218 <has_text text="-0.9857575" />
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219 <has_text text="-0.983684189899" />
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220 <has_text text="516.080116" />
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221 <has_text text="282.50076" />
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222 </assert_contents>
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223 </output>
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224 </test>
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225 <!-- test #2 - issue 6 -->
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226 <test>
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227 <param name="dataMatrix_in" value="input_dataMatrix.tsv"/>
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228 <param name="sampleMetadata_in" value="issue6_input_sampleMetadata.tsv"/>
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229 <param name="variableMetadata_in" value="input_variableMetadata.tsv"/>
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230 <param name="tesC" value="none"/>
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231 <param name="facC" value="k._10"/>
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232 <param name="labelFeatures" value="3"/>
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233 <param name="min_crossval_i" value="7"/>
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234 <param name="fdr_features" value="ALL"/>
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235 <param name="levCSV" value="k_3,k-4"/>
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236 <param name="matchingC" value="none"/>
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237 <output name="contrast_corcov">
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238 <assert_contents>
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239 <!-- column-labels line -->
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240 <has_text text="featureID" />
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241 <has_text text="factorLevel1" />
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242 <has_text text="factorLevel2" />
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243 <has_text text="correlation" />
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244 <has_text text="covariance" />
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245 <has_text text="vip4p" />
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246 <has_text text="vip4o" />
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247 <!-- first matched line -->
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248 <has_text text="M349.2383T700" />
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249 <has_text text="-0.1221966" />
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250 <has_text text="-917311734" />
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251 <has_text text="0.0304592" />
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252 <has_text text="0.104748883" />
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253 <has_text text="-0.002736415" />
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254 <has_text text="-0.0113968" />
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255 <has_text text="0.387723" />
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256 <has_text text="-0.3812168081" />
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257 <has_text text="0.154611878" />
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258 </assert_contents>
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259 </output>
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260 </test>
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261 <!-- test #3 - issue 8 -->
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262 <test>
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263 <param name="dataMatrix_in" value="input_dataMatrix.tsv"/>
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264 <param name="sampleMetadata_in" value="issue8_input_sampleMetadata.tsv"/>
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265 <param name="variableMetadata_in" value="input_variableMetadata.tsv"/>
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266 <param name="tesC" value="none"/>
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267 <param name="facC" value="k._10"/>
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268 <param name="labelFeatures" value="3"/>
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269 <param name="min_crossval_i" value="7"/>
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270 <param name="fdr_features" value="ALL"/>
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271 <param name="levCSV" value="k_3,k-4"/>
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272 <param name="matchingC" value="none"/>
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273 <output name="contrast_corcov">
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274 <assert_contents>
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275 <!-- column-labels line -->
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276 <has_text text="featureID" />
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277 <has_text text="factorLevel1" />
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278 <has_text text="factorLevel2" />
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279 <has_text text="correlation" />
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280 <has_text text="covariance" />
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281 <has_text text="vip4p" />
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282 <has_text text="vip4o" />
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283 <!-- k1 rejected by levCSV, leaving only k_3 and k-4 -->
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284 <not_has_text text="k1" />
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285 <not_has_text text="other" />
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286 <!-- first matched line -->
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287 <has_text text="M200.005T296" />
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288 <has_text text="-0.1829149760" />
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289 <has_text text="-115723402" />
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290 <has_text text="0.0892595" />
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291 <has_text text="0.00492288" />
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292 <has_text text="-0.00801895" />
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293 <has_text text="0.0005356178" />
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294 <has_text text="0.1848186" />
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295 <has_text text="-0.428802311" />
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296 <has_text text="0.0882045811" />
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297 </assert_contents>
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298 </output>
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299 </test>
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300 <!-- test #4 -->
0
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301 <test>
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302 <param name="dataMatrix_in" value="input_dataMatrix.tsv"/>
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303 <param name="sampleMetadata_in" value="input_sampleMetadata.tsv"/>
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304 <param name="variableMetadata_in" value="input_variableMetadata.tsv"/>
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305 <param name="tesC" value="kruskal"/>
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306 <param name="facC" value="k10"/>
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307 <param name="pairSigFeatOnly" value="FALSE"/>
2
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308 <param name="labelFeatures" value="3"/>
14
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309 <param name="min_crossval_i" value="7"/>
13
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310 <param name="fdr_features" value="250"/>
0
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311 <param name="levCSV" value="k[12],k[3-4]"/>
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312 <param name="matchingC" value="regex"/>
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313 <output name="contrast_corcov">
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314 <assert_contents>
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315 <!-- column-labels line -->
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316 <has_text text="featureID" />
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317 <has_text text="factorLevel1" />
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318 <has_text text="factorLevel2" />
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319 <has_text text="correlation" />
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320 <has_text text="covariance" />
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321 <has_text text="vip4p" />
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322 <has_text text="vip4o" />
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323 <has_text text="level1Level2Sig" />
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324 <!-- first matched line -->
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325 <has_text text="M349.2383T700" />
13
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326 <has_text text="-0.49037231902" />
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327 <has_text text="-2111932280.94" />
7
066b1f409e9f planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e73fabe1b3c871abbcb2e89914c181149c8e2066
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328 <has_text text="0.4914638" />
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329 <has_text text="0.01302117" />
13
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330 <has_text text="-0.049216260" />
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diff changeset
331 <has_text text="-0.00152098716" />
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332 <has_text text="2.0603074801" />
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diff changeset
333 <has_text text="-0.60020597" />
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334 <has_text text="-0.3623876130" />
0
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335 <!-- second matched line -->
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336 <has_text text="M207.9308T206" />
12
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diff changeset
337 <has_text text="0.504885262" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
338 <has_text text="293403792" />
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
339 <has_text text="0.207196379" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
340 <has_text text="0.04438632" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
341 <has_text text="0.020749097" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
342 <has_text text="0.005184709" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
343 <has_text text="1.47082346" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
344 <has_text text="2.24325407" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
345 <has_text text="0.38157919" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
346 <has_text text="0.610536188" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
347 </assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
348 </output>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
349 <output name="contrast_salience">
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
350 <assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
351 <!-- column-labels line -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
352 <has_text text="featureID" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
353 <has_text text="salientLevel" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
354 <has_text text="salienceRCV" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
355 <has_text text="salience" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
356 <!-- first three matched lines -->
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
357 <has_text text="M207.0654T373" /><has_text text="k4" /><has_text text="0.822733190" /><has_text text="134.087771" /><has_text text="3.9994434" /><has_text text="207.0654" /><has_text text="373" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
358 <has_text text="M222.9585T226" /><has_text text="k2" /><has_text text="0.761200229" /><has_text text="87.3672719" /><has_text text="3.9995358" /><has_text text="222.9585" /><has_text text="226" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
359 <has_text text="M235.0975T362" /><has_text text="k4" /><has_text text="0.209363850" /><has_text text="77.6255643" /><has_text text="3.99606600" /><has_text text="235.0975" /><has_text text="362" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
360 </assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
361 </output>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
362 </test>
14
90708fdbc22d "planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 5fd9687d543a48a715b1180caf93abebebd58b0e"
eschen42
parents: 13
diff changeset
363 <!-- test #5 -->
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
364 <test>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
365 <param name="dataMatrix_in" value="input_dataMatrix.tsv"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
366 <param name="sampleMetadata_in" value="input_sampleMetadata.tsv"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
367 <param name="variableMetadata_in" value="input_variableMetadata.tsv"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
368 <param name="tesC" value="kruskal"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
369 <param name="facC" value="k10"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
370 <param name="pairSigFeatOnly" value="TRUE"/>
2
e03582f26617 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 7682e8e7ae2bfb926d94b414b9a1649389f33582
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parents: 1
diff changeset
371 <param name="labelFeatures" value="3"/>
14
90708fdbc22d "planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 5fd9687d543a48a715b1180caf93abebebd58b0e"
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parents: 13
diff changeset
372 <param name="min_crossval_i" value="7"/>
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
373 <param name="fdr_features" value="ALL"/>
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
374 <param name="levCSV" value="k[12],k[3-4]"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
375 <param name="matchingC" value="regex"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
376 <output name="contrast_corcov">
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
377 <assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
378 <!-- column-labels line -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
379 <has_text text="featureID" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
380 <has_text text="factorLevel1" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
381 <has_text text="factorLevel2" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
382 <has_text text="correlation" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
383 <has_text text="covariance" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
384 <has_text text="vip4p" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
385 <has_text text="vip4o" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
386 <has_text text="level1Level2Sig" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
387 <!-- first matched line -->
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
388 <has_text text="M200.005T296" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
389 <has_text text="0.0050579682" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
390 <has_text text="2607493" />
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
391 <has_text text="0.1157346" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
392 <has_text text="0.0647860" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
393 </assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
394 </output>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
395 <output name="contrast_salience">
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
396 <assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
397 <!-- column-labels line -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
398 <has_text text="featureID" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
399 <has_text text="salientLevel" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
400 <has_text text="salienceRCV" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
401 <has_text text="salience" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
402 <!-- first three matched lines -->
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
403 <has_text text="M207.0654T373" /><has_text text="k4" /><has_text text="0.822733190" /><has_text text="134.087771" /><has_text text="3.9994434" /><has_text text="207.0654" /><has_text text="373" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
404 <has_text text="M222.9585T226" /><has_text text="k2" /><has_text text="0.761200229" /><has_text text="87.3672719" /><has_text text="3.9995358" /><has_text text="222.9585" /><has_text text="226" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
405 <has_text text="M235.0975T362" /><has_text text="k4" /><has_text text="0.209363850" /><has_text text="77.6255643" /><has_text text="3.99606600" /><has_text text="235.0975" /><has_text text="362" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
406 </assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
407 </output>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
408 </test>
14
90708fdbc22d "planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 5fd9687d543a48a715b1180caf93abebebd58b0e"
eschen42
parents: 13
diff changeset
409 <!-- test #6 -->
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
410 <test>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
411 <param name="dataMatrix_in" value="input_dataMatrix.tsv"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
412 <param name="sampleMetadata_in" value="input_sampleMetadata.tsv"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
413 <param name="variableMetadata_in" value="input_variableMetadata.tsv"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
414 <param name="tesC" value="none"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
415 <param name="facC" value="k10"/>
2
e03582f26617 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 7682e8e7ae2bfb926d94b414b9a1649389f33582
eschen42
parents: 1
diff changeset
416 <param name="labelFeatures" value="3"/>
14
90708fdbc22d "planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 5fd9687d543a48a715b1180caf93abebebd58b0e"
eschen42
parents: 13
diff changeset
417 <param name="min_crossval_i" value="7"/>
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
418 <param name="fdr_features" value="ALL"/>
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
419 <param name="levCSV" value="k[12],k[3-4]"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
420 <param name="matchingC" value="regex"/>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
421 <output name="contrast_corcov">
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
422 <assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
423 <!-- column-labels line -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
424 <has_text text="featureID" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
425 <has_text text="factorLevel1" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
426 <has_text text="factorLevel2" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
427 <has_text text="correlation" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
428 <has_text text="covariance" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
429 <has_text text="vip4p" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
430 <has_text text="vip4o" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
431 <!-- first matched line -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
432 <has_text text="M349.2383T700" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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parents: 12
diff changeset
433 <has_text text="-0.499225" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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parents: 12
diff changeset
434 <has_text text="-2135165209" />
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
435 <has_text text="0.5246766" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
436 <has_text text="0.0103341" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
437 <!-- second matched line -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
438 <has_text text="M207.9308T206" />
12
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
eschen42
parents: 11
diff changeset
439 <has_text text="0.4927151212" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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parents: 12
diff changeset
440 <has_text text="284608538" />
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
441 <has_text text="0.2111623" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
442 <has_text text="0.0488654" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
443 </assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
444 </output>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
445 <output name="contrast_salience">
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
446 <assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
447 <!-- column-labels line -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
448 <has_text text="featureID" />
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
449 <has_text text="salientLevel" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
450 <has_text text="salienceRCV" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
451 <has_text text="salience" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
452 <!-- first three matched lines -->
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
453 <has_text text="M207.0654T373" /><has_text text="k4" /><has_text text="0.822733190" /><has_text text="134.087771" /><has_text text="3.9994434" /><has_text text="207.0654" /><has_text text="373" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
454 <has_text text="M222.9585T226" /><has_text text="k2" /><has_text text="0.761200229" /><has_text text="87.3672719" /><has_text text="3.9995358" /><has_text text="222.9585" /><has_text text="226" />
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
455 <has_text text="M235.0975T362" /><has_text text="k4" /><has_text text="0.209363850" /><has_text text="77.6255643" /><has_text text="3.99606600" /><has_text text="235.0975" /><has_text text="362" />
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
456 </assert_contents>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
457 </output>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
458 </test>
14
90708fdbc22d "planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 5fd9687d543a48a715b1180caf93abebebd58b0e"
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parents: 13
diff changeset
459 <!-- test #7 -->
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
460 <test>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
461 <param name="dataMatrix_in" value="issue1_input_dataMatrix.tsv"/>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
462 <param name="sampleMetadata_in" value="issue1_input_sampleMetadata.tsv"/>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
463 <param name="variableMetadata_in" value="issue1_input_variableMetadata.tsv"/>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
464 <param name="tesC" value="none"/>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
465 <param name="facC" value="tissue_flowering"/>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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diff changeset
466 <param name="labelFeatures" value="3"/>
14
90708fdbc22d "planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 5fd9687d543a48a715b1180caf93abebebd58b0e"
eschen42
parents: 13
diff changeset
467 <param name="min_crossval_i" value="7"/>
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
468 <param name="fdr_features" value="ALL"/>
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
469 <param name="levCSV" value="*"/>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
470 <param name="matchingC" value="wildcard"/>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
471 <output name="contrast_corcov">
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
472 <assert_contents>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
473 <!-- column-labels line -->
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
474 <has_text text="featureID" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
475 <has_text text="factorLevel1" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
476 <has_text text="factorLevel2" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
477 <has_text text="correlation" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
478 <has_text text="covariance" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
479 <has_text text="vip4p" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
480 <has_text text="vip4o" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
481 <!-- first matched line -->
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
482 <has_text text="NM516T251" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
483 <has_text text="flower_yes" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
484 <has_text text="other" />
12
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
eschen42
parents: 11
diff changeset
485 <has_text text="0.3499550705" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
486 <has_text text="11.609255" />
7
066b1f409e9f planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e73fabe1b3c871abbcb2e89914c181149c8e2066
eschen42
parents: 6
diff changeset
487 <has_text text="0.43664386" />
066b1f409e9f planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e73fabe1b3c871abbcb2e89914c181149c8e2066
eschen42
parents: 6
diff changeset
488 <has_text text="0.587701897" />
066b1f409e9f planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e73fabe1b3c871abbcb2e89914c181149c8e2066
eschen42
parents: 6
diff changeset
489 <has_text text="0.026082688" />
066b1f409e9f planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e73fabe1b3c871abbcb2e89914c181149c8e2066
eschen42
parents: 6
diff changeset
490 <has_text text="0.0437742145" />
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
491 <has_text text="516.0845" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
492 <has_text text="250.8762" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
493 </assert_contents>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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parents: 5
diff changeset
494 </output>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
495 <output name="contrast_salience">
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
496 <assert_contents>
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
497 <!-- column-labels line -->
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
498 <has_text text="featureID" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
499 <has_text text="salientLevel" />
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
500 <has_text text="salienceRCV" />
6
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
501 <has_text text="salience" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
502 <has_text text="mz" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
parents: 5
diff changeset
503 <has_text text="rt" />
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
eschen42
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diff changeset
504 <!-- first matched line -->
13
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505 <has_text text="NM517T428" /><has_text text="flower_yes" /><has_text text="0.02765631" /><has_text text="7.8343993" /><has_text text="1.27813793" /><has_text text="517.121714" /><has_text text="428.306854248" />
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506 <has_text text="NM517T426_1" /><has_text text="0.0290065" /><has_text text="7.7151305" /><has_text text="1.2758886" /><has_text text="517.09367125" /><has_text text="426.233886719" />
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507 <has_text text="NM516T284_2" /><has_text text="0.022883902" /><has_text text="7.6379724" /><has_text text="1.25603610" /><has_text text="516.082005177" /><has_text text="283.569198608" />
6
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508 </assert_contents>
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509 </output>
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510 </test>
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511 <!-- test #8 -->
10
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512 <test>
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513 <param name="dataMatrix_in" value="input_dataMatrix.tsv"/>
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514 <param name="sampleMetadata_in" value="issue6_input_sampleMetadata.tsv"/>
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515 <param name="variableMetadata_in" value="input_variableMetadata.tsv"/>
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516 <param name="tesC" value="none"/>
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517 <param name="facC" value="k._10"/>
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518 <param name="labelFeatures" value="3"/>
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519 <param name="min_crossval_i" value="7"/>
13
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520 <param name="fdr_features" value="ALL"/>
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521 <param name="levCSV" value="k1,k.2"/>
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522 <param name="matchingC" value="none"/>
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523 <output name="contrast_corcov">
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524 <assert_contents>
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525 <!-- column-labels line -->
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526 <has_text text="featureID" />
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527 <has_text text="factorLevel1" />
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528 <has_text text="factorLevel2" />
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529 <has_text text="correlation" />
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530 <has_text text="covariance" />
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531 <has_text text="vip4p" />
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532 <has_text text="vip4o" />
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533 <!-- first matched line -->
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534 <has_text text="M349.2383T700" />
12
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535 <has_text text="0.61594030" />
13
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536 <has_text text="3489481837.9" />
11
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537 <has_text text="0.54672558" />
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538 <has_text text="0.3920409" />
10
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539 <!-- second matched line -->
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540 <has_text text="M207.9308T206" />
12
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541 <has_text text="-0.89716403" />
13
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542 <has_text text="-585563327.7" />
11
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543 <has_text text="0.270297" />
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544 <has_text text="0.037661" />
10
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545 </assert_contents>
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546 </output>
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547 </test>
0
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548 </tests>
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549 <help><![CDATA[
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550
13
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551 **Run OPLS-DA Contrasts of Univariate Results**
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552 -----------------------------------------------
0
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553
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554 **Author** - Arthur Eschenlauer (University of Minnesota, esch0041@umn.edu)
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555
12
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556 **Release Notes** - https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper#release-notes
0
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557
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558 Motivation
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559 ----------
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560
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561 OPLS-DA and the SIMCA S-PLOT (Wiklund *et al.*, 2008) may be employed to draw attention to metabolomic features that are potential biomarkers, i.e. features that are potentially useful when assigning a sample to one of two classes (e.g. Sun *et al.*, 2016). Workflow4Metabolomics (W4M, Giacomoni *et al.*, 2014, Guitton *et al.*, 2017) provides a suite of tools for preprocessing and statistical analysis of LC-MS, GC-MS, and NMR metabolomics data; however, it does not (as of release 3.2) include a tool for making the equivalent of an S-PLOT.
0
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562
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563 The S-PLOT is computed from mean-centered, pareto-scaled data. This plot presents the correlation of the first score vector from an OPLS-DA model with the sample-variables used to produce that model versus the covariance of the scores with the sample-variables. For OPLS-DA, the first score vector represents the variation among the sample-variables that is related to the predictor (i.e., the contrasting factor); the second score vector, variation that is orthogonal to the predictor.
0
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564
1
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565 The primary aims of this tool are:
0
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566
1
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567 - To compute and visualize multiple contrasts with OPLS-DA and the covariance vs. correlation plot.
0
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568 - To write the results to data files for use in further multivariate analysis or visualization.
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569
1
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570 Note: This tool only supports categorical factors with non-numeric level-names.
0
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571
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572 Description
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573 -----------
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574
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575 The purpose of the 'OPLS-DA Contrasts' tool is to visualize GC-MS or LC-MS features that are possible biomarkers.
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576
4
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577 The W4M 'Univariate' tool (Th]]>&#233;<![CDATA[venot *et al.*, 2015) adds the results of family-wise corrected pairwise significance-tests as columns of the **variableMetadata** dataset.
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578 For instance, if Kruskal-Wallis testing were perfomred on a column named 'cluster' in sampleMetadata that has values 'k1' and 'k2' and at least one other value:
0
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579
2
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580 - A column of variableMetadata would be labelled 'cluster_kruskal_sig' and would have values '1' and '0'; when the samples are grouped by 'cluster', '1' means that there is strong evidence against the hypothesis that there is no difference among the intensities for the feature across all sample-groups.
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581 - A column of variableMetadata would be labelled 'cluster_kruskal_k1.k2_sig' and would have values '1' and '0', where '1' means that there is significant evidence against the hypothesis that samples from sampleMetadata whose 'cluster' column contains 'k1' or 'k2' have the same intensity for that feature.
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582
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583 The 'OPLS-DA Contrasts' tool produces graphics and data for OPLS-DA contrasts of feature-intensities between significantly different pairs of factor-levels. For each factor-level, the tool performs a contrast with all other factor-levels combined and then separately with each other factor-level.
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584
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585 **Along the left-to-right axis, the plots show the supervised projection of the variation explained by the predictor** (i.e., the factor specified when invoking the tool); **the top-to-bottom axis displays the variation that is orthogonal to the predictor level** (i.e., independent of it).
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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586
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587 Although this tool can be used in a purely exploratory manner by supplying the variableMetadata file without the columns added by the W4M 'Univariate' tool, **a preferable workflow may be to use univariate testing to exclude features that are not significantly different and then to use OPLS-DA to visualize the differences identified in univariate testing** (Th]]>&#233;<![CDATA[venot *et al.*, 2015); an appropriate exception would be to visualize contrasts of a specific list of metabolites. If you do exclude features, however, make sure that you set the advanced parameter "How many features for p-value calculation?" accordingly.
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588
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589 It must be stressed that there may be no *single* definitive computational approach to select features that are reliable biomarkers, especially from a small number of samples or experiments. A few possible choices are:
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590
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591 - picking features with maximum loadings along the projection parallel to the predictor (loadp),
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592 - examining extreme values on S-PLOTs
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593 - examining "variable importance in projection VIP for OPLS-DA" (Galindo-Prieto *et al.* 2014), and
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594 - examining a feature's "selectivity ratio" (Rajalahti *et al.*, 2009).
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595
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596 In this spirit, this tool reports the S-PLOT covariance and correlation (Wiklund *op. cit.*) and VIP metrics, and it introduces an informal "salience" metric to flag features that may merit attention without dimensional reduction; future versions may add selectivity ratio.
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597
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598 For a more systematic approach to biomarker identification, please consider the W4M 'biosigner' tool (Rinuardo *et al.* 2016), which applies three different identification metrics to the selection process. Regardless of how any potential biomarker is identified, further validation analysis (e.g., independent confirmatory experiments) is needed before it can be recommended for general application.
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599
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600
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601 W4M Workflow Position
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602 ---------------------
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603
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604 - Upstream tool: **Univariate** (category: Statistical Analysis) or any **Preprocessing** tool that produces or updates a 'variableMetadata' file.
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605 - Downstream tool categories: **Statistical Analysis**
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606
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607 Input files
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608 -----------
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609
1
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610 +----------------------+-----------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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611 | File | Format |
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612 +======================+===========+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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613 | Data matrix | tabular |
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614 +----------------------+-----------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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615 | Sample metadata | tabular |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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616 +----------------------+-----------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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617 | Variable metadata | tabular |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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618 +----------------------+-----------+
0
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619
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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620 Output files
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621 ------------
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622
1
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623 +-------------------------------------------+-----------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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624 | File | Format |
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625 +===========================================+===========+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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626 | Contrast detail | pdf |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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627 +-------------------------------------------+-----------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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628 | Contrast "corrlation and covariance" data | tabular |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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629 +-------------------------------------------+-----------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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630 | Feature "salience" data | tabular |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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631 +-------------------------------------------+-----------+
0
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632
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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633 Parameters
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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634 ----------
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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635
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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636 [IN] Data matrix file
1
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637 | variable x sample **dataMatrix** (tabular separated values) file of the numeric data matrix, with '.' as decimal, and 'NA' for missing values; the table must not contain metadata apart from row and column names; the row and column names must be identical to the rownames of the sample and variable metadata, respectively (see below)
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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638 |
0
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639
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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640 [IN] Sample metadata file
1
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641 | sample x metadata **sampleMetadata** (tabular separated values) file of the numeric and/or character sample metadata, with '.' as decimal and 'NA' for missing values
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642 |
0
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643
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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644 [IN] Variable metadata file
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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645 | variable x metadata **variableMetadata** (tabular separated values) file of the numeric and/or character variable metadata, with '.' as decimal and 'NA' for missing values
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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646 |
0
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647
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648 [IN] Test
1
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649 | Name of the **statistical test** - a component of column names in variable metadata table
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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650 | May be one of 'none', 'ttest', 'gwilcoxon', 'anova', 'kruskal', 'pearson', 'spearman'
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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651 |
0
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652
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653 [IN] Factor of interest
1
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654 | Name of the **column of sampleMetadata** corresponding to the qualitative or quantitative variable
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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655 |
0
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656
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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657 [IN] Retain only pairwise-significant features
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658 | *Note that when 'Test' is 'none', all features are included in the analysis and this parameter is not settable.*
1
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659 | When **true**, for each contrast of two levels, include only those features which pass the significance threshold for that contrast. Choosing true results in an OPLS-DA model that better reflects and visualizes the difference detected by univariate analysis, with somewhat increased reliability of prediction (as assessed by cross-validation).
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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660 | When **false**, include all features that pass the significance threshold when testing for difference across all factor-levels. This choice produces a plot that displays more features but is not necessarily more informative.
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661 |
0
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662
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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663 [IN] Levels of interest
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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664 | Comma-separated **level-names** (or comma-less regular expressions to match level-names) to consider in analysis; must match at least two levels; may include wild cards or regular expressions.
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665 |
0
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666
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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667 [IN] Level-name matching
1
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668 | Indicator of **how levels are to be specified generically** (if at all) - wild cards, regular expressions, or none (no generic matching).
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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669 |
0
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670
2
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671 [IN] Label how many extreme features
e03582f26617 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 7682e8e7ae2bfb926d94b414b9a1649389f33582
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672 | Specify the number of features at each of the loading-extremes that should be labelled (with the name of the feature) on the covariance-vs.-correlation plot; specify 'ALL' to label all features; this choice has no effect on the OPLS-DA loadings plot.
e03582f26617 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 7682e8e7ae2bfb926d94b414b9a1649389f33582
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673 |
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674
13
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675 [IN] (Advanced) C-plot Y-axis
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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676 | Choose whether C-plots should plot the correlation (the default) or the covariance *vs.* VIP.
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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677 |
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678
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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679 [IN] (Advanced) Produce predictor C-plot
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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680 | Choose whether a C-plot should be produced for the projections parallel to the predictor.
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681 |
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diff changeset
682
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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683 [IN] (Advanced) Produce orthogonal C-plot
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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684 | Choose whether a C-plot should be produced for the projections orthogonal to the predictor.
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685 |
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686
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687 [IN] (Advanced) How many features for p-value calculation?
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688 | You will need to use this option when statistical criteria have previously been applied to remove features in the data matrix. This is important for adjusting the p-values for correlation of the scores with each feature; this adjustment is necessary to avoid underestimation of the p-values. If this is applicable, specify the sum of the number of features removed and the number of features in the data matrix.
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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689 |
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690
0
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691 [OUT] Contrast-detail output PDF
12
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692 | File containing several plots for each two-projection OPLS-DA analysis.
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693
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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694 - (first row, left) **correlation-versus-covariance plot** of OPLS-DA results
0
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695
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696 - This is a work-alike for the S-PLOT described in Wiklund, (*op. cit.*), ignoring samples with missing values;
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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697 - point-color becomes saturated as the "variable importance in projection to the predictive components" (VIP\ :subscript:`4,p` from Galindo-Prieto *op. cit.*) ranges from 0.83 and 1.21 (Mehmood *et al.* 2012), for use to identify features for consideration as biomarkers;
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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698 - plot symbols are diamonds when the p-value of the correlation, adjusted for family-wise error rate (Yekutieli *et al.*, 2001), is greater than 0.05, circles when it is less than 0.01, and triangles when between 0.01 and 0.05.
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699 - (second row, left) **model-overview plot** for the two projections; grey bars are the correlation coefficient for the fitted data; black bars indicate performance in cross-validation tests (Th]]>&#233;<![CDATA[venot, 2017)
7bd523ca1f9a planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit cafda5095a79ce2376325b57337302f95137195d
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700 - (first row, right) OPLS-DA **scores-plot** for the two projections (Th]]>&#233;<![CDATA[venot *et al.*, 2015)
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2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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701 - (second row, right) **correlation-versus-covariance plot** of OPLS-DA results **orthogonal to the predictor** (see section "S-Plot of Orthogonal Component" in Wiklund, *op. cit.*, pp. 120-121; this characterizes variation of features that is *independent of the predictor*).
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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702 - (third row, left, when "**predictor C-plot**" is chosen under "Advanced") plot of the correlation (or covariance) vs. the VIP\ :subscript:`4,p` (Galindo-Prieto *op. cit.*), to assist in identifying features for consideration as biomarkers.
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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703 - (third row, right, when "**orthogonal C-plot**" is chosen under "Advanced") plot of the correlation (or covariance) vs. the VIP\ :subscript:`4,o` (*ibid.*), to assist in identifying features varying considerably without regard to the predictor.
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23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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704
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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705 [OUT] Contrast Correlation-Covarinace data TABULAR
1
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706 | A tab-separated values file of metadata for each feature for each contrast in which it was included.
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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707 | Thus, a given feature may appear many times, but *the combination of featureID, factorLevel1, and factorLevel2 will be unique.*
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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708 | This file has the following columns:
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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709
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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710 - **featureID** - feature identifier
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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711 - **factorLevel1** - factor-level 1
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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712 - **factorLevel2** - factor-level 2 (or "other" when contrasting factor-level 1 with all other levels)
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713 - **correlation**\ (t\ :subscript:`p`,X\ :subscript:`i`) - for this feature (i), correlation of sample intensities for this feature (X\ :subscript:`i`) with the OPLS-DA projection's first set of scores (t\ :subscript:`p`, i.e., the scores explaining the difference between the features), computed (omitting samples missing values) using the R *stats::cor* function with the 'pearson' method (R Core Team, 2018); this is negative when intensity for level 1 is greater than for level 2
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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714 - **covariance**\ (t\ :subscript:`p`,X\ :subscript:`i`) - computed as for correlation but using the R *stats::cov* function (*ibid.*) in lieu of *stats::cor*; this is also negative when intensity for level 1 is greater than for level 2
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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715 - **vip4p** - "variable importance in projection" to the predictive projection, VIP\ :subscript:`4,p` (Galindo-Prieto *op. cit.*)
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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716 - **vip4o** - "variable importance in projection" to the orthogonal projection, VIP\ :subscript:`4,o` (*ibid.*)
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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717 - **loadp** - variable loading for the predictive projection (Wiklund *op. cit.*)
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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718 - **loado** - variable loading for the orthogonal projection (*ibid.*)
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ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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719 - **cor_p_val_raw** - p-value for Fisher-transformed correlation (Fisher, 1921; Snedecor, 1980; see also https://en.wikipedia.org/wiki/Fisher_transformation), with no family-wise error-rate correction.
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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720 - **cor_p_value** - p-value for Fisher-transformed correlation, adjusted for family-wise error rate (Yekutieli *et al.*, 2001).
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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721 - **cor_ci_lower** - lower limit of 95% confidence interval for correlation, based on cor_p_value
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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722 - **cor_ci_upper** - upper limit of 95% confidence interval for correlation, based on cor_p_value
12
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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723 - **mz** - *m/z* ratio for feature, copied from input variableMetadata
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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724 - **rt** - retention time for feature, copied from input variableMetadata
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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725 - **level1Level2Sig** (Only present when a test other than "none" is chosen) - '1' when feature varies significantly across all classes (i.e., not pair-wise); '0' otherwise
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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726
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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727 [OUT] Feature "Salience" data TABULAR
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728 | Metrics for the "salient level" for each feature, i.e., the level at which the feature is more prominent than any other level. This is *not* at all related to the SIMCA OPLS-DA S-PLOT; rather, it is intended as a potential way to discover features for consideration as potential biomarkers without dimensionally reducting the data. This is a tab-separated values file having the following columns:
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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729
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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730 - **featureID** - feature identifier
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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731 - **salientLevel** - salient level, i.e., for the feature, the class-level having the greatest median intensity
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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732 - **salienceRCV** - salience robust coefficient of variation, i.e., for the feature, the mean absolute deviation of the intensity for the salient level divided by the median intensity for the salient level
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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733 - **relativeSalientDistance** - relative salient distance, i.e., for the feature, the distance between the two highest class-level medians divided by the square root of the mean absolute deviations of those two class-level's intensities
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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734 - **salience** - salience, i.e., for the feature, the median of the class-level having the greatest intensity divided by the mean of the medians for all class-levels
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2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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735 - **mz** - *m/z* ratio for feature, copied from input variableMetadata
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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736 - **rt** - retention time for feature, copied from input variableMetadata
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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737
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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738 Wild card patterns to match level-names
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
739 ---------------------------------------
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
740
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
741 "wild card" patterns may be used to select level-names.
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
742
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
743 - use '``?``' to match a single character
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
744 - use '``*``' to match zero or more characters
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
745 - the entire pattern must match the level name
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
746
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
747 For example
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
748
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
749 - '``??.le*``' matches '``my.level``' but not '``my.own.level``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
750 - '``*.level``' matches '``my.level``' and '``my.own.level``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
751 - '``*.level``' matches neither '``my.level``' nor '``my.own.level``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
752
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
753 Regular expression patterns to match level-names
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
754 ------------------------------------------------
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
755
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
756 "regular expression" patterns may be used to select level-names.
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
757
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
758 POSIX 1003.2 standard regular expressions allow precise pattern-matching and are exhaustively defined at:
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
759 http://pubs.opengroup.org/onlinepubs/9699919799/basedefs/V1_chap09.html
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
760
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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parents:
diff changeset
761 However, only a few basic building blocks of regular expressions need to be mastered for most cases:
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
762
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
763 - '``^``' matches the beginning of a level-name
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
764 - '``$``' matches the end of a level-name
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
765 - '``.``' outside of square brackets matches a single character
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
766 - '``*``' matches character specified immediately before zero or more times
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
767 - Square brackets specify a set of characters to be matched. Within square brackets:
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
768
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
769 - '``^``' as the first character specifies that the list of characters are those that should **not** be matched.
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
770 - '``-``' is used to specify ranges of characters
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
771
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
772 Caveat: The tool wrapper uses the comma ('``,``') to split a list of sample-level names, so **commas may not be used within regular expressions for this tool.**
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
773
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
774 First Example: Consider a field of level-names consisting of '``marq3,marq6,marq9,marq12,front3,front6,front9,front12``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
775
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
776 - The regular expression '``^front[0-9][0-9]*$``' will match the same sample-levels as '``front3,front6,front9,front12``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
777 - The regular expression '``^[a-z][a-z]3$``' will match the same sample-levels as '``front3,marq3``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
778 - The regular expression '``^[a-z][a-z]12$``' will match the same sample-levels as '``front12,marq12``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
779 - The regular expression '``^[a-z][a-z][0-9]$``' will match the same sample-levels as '``front3,front6,front9,marq3,marq6,marq9``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
780
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
781 Second Example: Consider these regular expression patterns as possible matches to a sample-level name '``AB0123``':
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
782
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
783 - '``^[A-Z][A-Z][0-9][0-9]*$``' - MATCHES '``**^AB0123$**``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
784 - '``^[A-Z][A-Z]*[0-9][0-9]*$``' - MATCHES '``**^AB0123$**``'
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
785 - '``^[A-Z][0-9]*``' - MATCHES '``**^A** B0123$``' - first character is a letter, '``*``' can specify zero characters, and end of line did not need to be matched.
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
786 - '``^[A-Z][A-Z][0-9]``' - MATCHES '``**^AB0** 123$``' - first two characters are letters aind the third is a digit.
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
787 - '``^[A-Z][A-Z]*[0-9][0-9]$``' - NO MATCH - the name does not end with the pattern '``[A-Z][0-9][0-9]$``', i.e., it ends with four digits, not two.
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
788 - '``^[A-Z][0-9]*$``' - NO MATCH - the pattern specifies that second character and all those that follow, if present, must be digits.
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
789
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
790 Working examples
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
791 ----------------
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
792
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
793 **Input files**
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
794
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
795 +-----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
796 | Download from URL |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
797 +===============================================================================================================================================+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
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parents: 8
diff changeset
798 | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/input_dataMatrix.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
799 +-----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
800 | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/input_sampleMetadata.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
801 +-----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
802 | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/input_variableMetadata.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
803 +-----------------------------------------------------------------------------------------------------------------------------------------------+
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
804
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
805 **Example 1:** Include in the analysis only features identified as pair-wise significant in the Univariate test.
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
806
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
807 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
808 | Input Parameter or Result | Value |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
809 +============================================+========================================================================================================================================+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
810 | Factor of interest | k10 |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
811 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
812 | Univariate Significance-Test | kruskal |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
813 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
814 | Retain only pairwise-significant features | Yes |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
815 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
816 | Levels of interest | k[12],k[3-4] |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
817 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
818 | Level-name matching | use regular expressions for matching level-names |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
819 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
820 | Number of features having extreme loadings | ALL |
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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parents: 0
diff changeset
821 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
822 | How many features for p-value calculation? | 250 |
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
823 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
824 | Output primary table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_corcov.tsv |
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
825 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
826 | Output salience table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_salience.tsv |
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
827 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
828 | Output figures PDF | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_detail.pdf |
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
829 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------+
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
830
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
831 **Example 2:** Include in the analysis only features identified as overall-significant in the Univariate test. Note that this even includes these features in contrasts where they were not determined to be pair-wise significant in the Univariate test. Thus, more features are included than in Example 1.
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
832
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
833 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
834 | Input Parameter or Result | Value |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
835 +============================================+============================================================================================================================================+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
836 | Factor of interest | k10 |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
837 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
838 | Univariate Significance-Test | kruskal |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
839 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
840 | Retain only pairwise-significant features | No |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
841 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
842 | Levels of interest | ``*`` |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
843 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
844 | Level-name matching | use wild cards for matching level-names |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
845 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
846 | Number of features having extreme loadings | 5 |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
847 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
848 | How many features for p-value calculation? | ALL |
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
849 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
850 | Output primary table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_corcov_all.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
851 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
852 | Output salience table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_salience_all.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
853 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
854 | Output figures PDF | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_detail_all.pdf |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
855 +--------------------------------------------+--------------------------------------------------------------------------------------------------------------------------------------------+
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
856
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
857 **Example 3:** Include all features in the analysis without regard to Univariate testing. Univariate testing is not even a pre-requisite to using the tool when 'none' is selected for the test. Thus, more features are included than in Example 2.
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
eschen42
parents:
diff changeset
858
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
859 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
860 | Input Parameter or Result | Value |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
861 +============================================+==============================================================================================================================================+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
862 | Factor of interest | k10 |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
863 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
864 | Univariate Significance-Test | none |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
865 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
866 | Levels of interest | k[12],k[3-4] |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
867 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
868 | Level-name matching | use regular expressions for matching level-names |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
869 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
870 | Number of features having extreme loadings | 0 |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
871 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
872 | How many features for p-value calculation? | ALL |
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
873 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
874 | Output primary table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_corcov_global.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
875 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
876 | Output salience table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_salience_global.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
877 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
878 | Output figures PDF | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_detail_global.pdf |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
879 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
1
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
880
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
881 **Example 4:** Analysis of a two-level factor (including all features). This suppresses the contrasts of "each factor vs. the aggregate of all the others".
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
eschen42
parents: 0
diff changeset
882
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
883 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
884 | Input Parameter or Result | Value |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
885 +============================================+==============================================================================================================================================+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
886 | Factor of interest | lohi |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
887 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
888 | Univariate Significance-Test | none |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
889 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
890 | Levels of interest | low,high |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
891 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
892 | Level-name matching | use regular expressions for matching level-names |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
893 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
894 | Number of features having extreme loadings | 3 |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
895 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
13
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
896 | How many features for p-value calculation? | ALL |
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
eschen42
parents: 12
diff changeset
897 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
9
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
898 | Output primary table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_corcov_lohi.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
899 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
900 | Output salience table | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_salience_lohi.tsv |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
901 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
902 | Output figures PDF | https://raw.githubusercontent.com/HegemanLab/w4mcorcov_galaxy_wrapper/master/tools/w4mcorcov/test-data/expected_contrast_detail_lohi.pdf |
06c51af11531 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit fda7ea61f0a082fd0c28730e471e66c92aaa04d0
eschen42
parents: 8
diff changeset
903 +--------------------------------------------+----------------------------------------------------------------------------------------------------------------------------------------------+
0
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904
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
905
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
906 Trademarks
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
907 ----------
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
908
4
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parents: 3
diff changeset
909 OPLS-DA, SIMCA, and S-PLOT are registered trademarks of the Umetrics company. http://umetrics.com/about-us/trademarks
0
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diff changeset
910
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
911
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
912 ]]></help>
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diff changeset
913 <citations>
5
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diff changeset
914 <!-- this tool -->
2
e03582f26617 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 7682e8e7ae2bfb926d94b414b9a1649389f33582
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diff changeset
915 <citation type="doi">10.5281/zenodo.1034784</citation>
13
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diff changeset
916 <!-- R project -->
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diff changeset
917 <citation type="bibtex"><![CDATA[
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diff changeset
918 @Manual{,
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diff changeset
919 title = {R: A Language and Environment for Statistical Computing},
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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diff changeset
920 author = {{R Core Team}},
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diff changeset
921 organization = {R Foundation for Statistical Computing},
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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diff changeset
922 address = {Vienna, Austria},
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diff changeset
923 year = {2018},
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diff changeset
924 url = {https://www.R-project.org/},
2ae2d26e3270 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit e89c652c0849eb1d5a1e6c9100c72c64a8d388b4
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diff changeset
925 }
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diff changeset
926 ]]></citation>
12
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diff changeset
927 <!-- Fisher_1921: Fisher z-transformation of correlation coefficient -->
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diff changeset
928 <citation type="bibtex"><![CDATA[
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diff changeset
929 @article{Fisher_1921,
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diff changeset
930 author = {Fisher, R. A.},
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diff changeset
931 title = {{On the probable error of a coefficient of correlation deduced from a small sample}},
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diff changeset
932 journal = {Metron},
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diff changeset
933 year = {1921},
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diff changeset
934 volume = {1},
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diff changeset
935 pages = {3--32},
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diff changeset
936 note = {Defines the Fisher z-transformation of a coefficient of correlation. Citation adapted from http://www.citeulike.org/group/894/article/2344770},
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diff changeset
937 url = {https://digital.library.adelaide.edu.au/dspace/bitstream/2440/15169/1/14.pdf},
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diff changeset
938 }
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diff changeset
939 ]]></citation>
0
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diff changeset
940 <!-- Galindo_Prieto_2014 Variable influence on projection (VIP) for OPLS -->
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941 <citation type="doi">10.1002/cem.2627</citation>
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diff changeset
942 <!-- Giacomoni_2014 W4M 2.5 -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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943 <citation type="doi">10.1093/bioinformatics/btu813</citation>
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diff changeset
944 <!-- Guitton_2017 W4M 3.0 -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
945 <citation type="doi">10.1016/j.biocel.2017.07.002</citation>
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diff changeset
946 <!-- Mehmood_2012 PLS-based variable-selection -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
947 <citation type="doi">10.1186/1748-7188-6-27</citation>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
948 <!-- Rajalahti_2009 Biomarker discovery using selectivity ratio -->
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949 <citation type="doi">10.1016/j.chemolab.2008.08.004</citation>
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diff changeset
950 <!-- Rinuardo 2016 -->
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diff changeset
951 <citation type="doi">10.3389/fmolb.2016.00026</citation>
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diff changeset
952 <!-- Sun_2016 Urinary Biomarkers for adolescent idiopathic scoliosis -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
953 <citation type="doi">10.1038/srep22274</citation>
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parents: 11
diff changeset
954 <!-- Snedecor_1980: Fisher z-transformation of correlation coefficient -->
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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diff changeset
955 <citation type="bibtex"><![CDATA[
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diff changeset
956 @book{Snedecor_1980,
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diff changeset
957 author = {Snedecor, George W. and Cochran, William G.},
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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diff changeset
958 title = {Statistical methods},
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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parents: 11
diff changeset
959 publisher = {Iowa State University Press},
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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diff changeset
960 year = {1980},
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diff changeset
961 pages = {186},
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diff changeset
962 isbn = {0813815606},
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diff changeset
963 language = {eng},
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diff changeset
964 keyword = {Statistics, Statistics as Topic -- methods},
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diff changeset
965 lccn = {80014582},
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diff changeset
966 edition = {7th ed..},
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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diff changeset
967 address = {Ames, Iowa},
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diff changeset
968 }
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diff changeset
969 ]]></citation>
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diff changeset
970 <!-- Thevenot_2015 Urinary metabolome statistics -->
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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971 <citation type="doi">10.1021/acs.jproteome.5b00354</citation>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
972 <!-- ropls package -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
973 <citation type="bibtex"><![CDATA[
1
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diff changeset
974 @incollection{Thevenot_ropls_2017,
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diff changeset
975 author = {Th{\'{e}}venot, Etienne A.},
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diff changeset
976 title = {ropls: PCA, PLS(-DA) and OPLS(-DA) for multivariate analysis and feature selection of omics data},
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diff changeset
977 publisher = {bioconductor.org},
0c2ad44b6c9c planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 01d4a951cf09e7b88fcec96b8043bc7568cc5c92
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diff changeset
978 year = {2017},
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diff changeset
979 doi = {10.18129/B9.bioc.ropls},
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diff changeset
980 booktitle = {Bioconductor: Open source software for bioinformatics},
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diff changeset
981 address = {Roswell Park Cancer Institute},
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diff changeset
982 }
0
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983 ]]></citation>
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diff changeset
984 <!-- Wiklund_2008 OPLS-DA and S-PLOT -->
0
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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diff changeset
985 <citation type="doi">10.1021/ac0713510</citation>
12
ddaf84e15d06 planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit 6775c83b89d9d903c81a2229cdc200fc93538dfe-dirty
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diff changeset
986 <!-- Yekutieli_2001 The control of the false discovery rate in multiple testing under dependency -->
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987 <citation type="doi">10.1214/aos/1013699998</citation>
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988 </citations>
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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989 <!--
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990 vim:et:sw=4:ts=4
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991 -->
23f9fad4edfc planemo upload for repository https://github.com/HegemanLab/w4mcorcov_galaxy_wrapper/tree/master commit bd26542b811de06c1a877337a2840a9f899c2b94
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992 </tool>