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+# Univariate parametric and non-parametric hypothesis testing with correction for multiple testing
+
+A Galaxy module from the [Workflow4metabolomics](http://workflow4metabolomics.org) project.
+
+Status: [![Build Status](https://travis-ci.org/workflow4metabolomics/univariate.svg?branch=master)](https://travis-ci.org/workflow4metabolomics/univariate).
+
+## Description
+
+**Version:** 2.1.1   
+**Date:** 2015-09-30  
+**Author:** Marie Tremblay-Franco (INRA, MetaToul, MetaboHUB, W4M Core Development Team) and Etienne A. Thevenot (CEA, LIST, MetaboHUB, W4M Core Development Team)    
+**Email:** [marie.tremblay-franco(at)toulouse.inra.fr](mailto:marie.tremblay-franco@toulouse.inra.fr); [etienne.thevenot(at)cea.fr](mailto:etienne.thevenot@cea.fr)  
+**Citation:** Thevenot E.A., Roux A., Xu Y., Ezan E. and Junot C. (2015). Analysis of the human adult urinary metabolome variations with age, body mass index and gender by implementing a comprehensive workflow for univariate and OPLS statistical analyses. *Journal of Proteome Research*, **14**:3322-3335. [doi:10.1021/acs.jproteome.5b00354](http://dx.doi.org/10.1021/acs.jproteome.5b00354)  
+**Reference history:** [W4M00001a_sacurine-subset-statistics](http://galaxy.workflow4metabolomics.org/history/list_published), [W4M00004_mtbls1](http://galaxy.workflow4metabolomics.org/history/list_published)  
+**Licence:** CeCILL  
+**Funding:** Agence Nationale de la Recherche ([MetaboHUB](http://www.metabohub.fr/index.php?lang=en&Itemid=473) national infrastructure for metabolomics and fluxomics, ANR-11-INBS-0010 grant)
+
+## Installation
+
+ * Configuration file: **univariate_config.xml**  
+ * Image file: 
+  + **static/images/univariate_workflowPositionImage.png**   
+ * Wrapper file: **univariate_wrapper.R**  
+ * Script file: **univariate_script.R**  
+ * R packages  
+  + **batch** from CRAN: `install.packages("batch", dep=TRUE)`.
+  + **PMCMR** from Bioconductor: `install.packages("PMCMR", dep=TRUE)`.
+
+## Tests
+
+The code in the wrapper can be tested by running the **tests/univariate_tests.R** in R  
+
+## News
+
+## CHANGES IN VERSION 2.1.1  
+
+ * Internal handling of 'NA' p-values (e.g. when intensities are identical in all samples).