| 0 | 1 # ----------------------------------------------------------------------# | 
|  | 2 # Copyright (c) 2011, Richard Lupat & Jason Li. | 
|  | 3 # | 
|  | 4 # > Source License < | 
|  | 5 # This file is part of CONTRA. | 
|  | 6 # | 
|  | 7 #    CONTRA is free software: you can redistribute it and/or modify | 
|  | 8 #    it under the terms of the GNU General Public License as published by | 
|  | 9 #    the Free Software Foundation, either version 3 of the License, or | 
|  | 10 #    (at your option) any later version. | 
|  | 11 # | 
|  | 12 #    CONTRA is distributed in the hope that it will be useful, | 
|  | 13 #    but WITHOUT ANY WARRANTY; without even the implied warranty of | 
|  | 14 #    MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the | 
|  | 15 #    GNU General Public License for more details. | 
|  | 16 # | 
|  | 17 #    You should have received a copy of the GNU General Public License | 
|  | 18 #    along with CONTRA.  If not, see <http://www.gnu.org/licenses/>. | 
|  | 19 # | 
|  | 20 # | 
|  | 21 #-----------------------------------------------------------------------# | 
|  | 22 # Last Updated : 05 October 2011 16:43PM | 
|  | 23 | 
|  | 24 def target_breakdown(filename, maxRegionSize, targetRegionSize, out_fname): | 
|  | 25 	from math import ceil | 
|  | 26 | 
|  | 27 	a	= open(filename) | 
|  | 28 	output 	= open(out_fname, "w") | 
|  | 29 | 
|  | 30 	for x in a: | 
|  | 31 		x 	= x.split() | 
|  | 32 		chr 	= x[0] | 
|  | 33 		start 	= int(x[1]) | 
|  | 34 		end	= int(x[2]) | 
|  | 35 		info	= "" | 
|  | 36 		if (len(x) > 3): | 
|  | 37 			info	= x[3] | 
|  | 38 | 
|  | 39 		regionSize = end-start | 
|  | 40 | 
|  | 41 		if regionSize > maxRegionSize: | 
|  | 42 			seg	= ceil(regionSize/float(targetRegionSize)) | 
|  | 43 			limit	= ceil(regionSize/float(seg)) | 
|  | 44 | 
|  | 45 			s_end = start | 
|  | 46 			for i in range(int(seg)): | 
|  | 47 				s_start = s_end | 
|  | 48 				s_end = int(start + (limit*(i+1))) | 
|  | 49 				if s_end > end: | 
|  | 50 					s_end = end | 
|  | 51 				output.write("\t".join([chr, str(s_start), str(s_end), info+"(SPLIT)"])+"\n") | 
|  | 52 		else: | 
|  | 53 			output.write("\t".join([chr, str(start), str(end), info])+"\n") | 
|  | 54 | 
|  | 55 	output.close() | 
|  | 56 |