--- a/README.rst	Tue Apr 19 00:39:29 2022 +0000
+++ b/README.rst	Fri Aug 19 00:29:16 2022 +0000
@@ -9,7 +9,9 @@
 
 This document is designed to provide details on the compute environment
 required for Alphafold operation, and the Galaxy job destination
-settings to run the wrapper.
+settings to run the wrapper. We strongly suggest reading this entire document
+to ensure that your setup is compatible with the hardware that you are
+deploying to.
 
 For full details on Alphafold requirements, see
 https://github.com/deepmind/alphafold.
@@ -163,11 +165,9 @@
 A few parameters can be customized with the use of environment variables set in the job destination:
 
 - ``ALPHAFOLD_DB``: path to the reference database root (default ``/data``)
-- ``ALPHAFOLD_AA_LENGTH_MIN``: minimum accepted sequence length (default ``30``)
-- ``ALPHAFOLD_AA_LENGTH_MAX``: maximum accepted sequence length (default ``2000``)
-
-For the last two, these could be set to ``0`` and ``50000`` respectively to remove the valiation entirely.
-
+- ``ALPHAFOLD_USE_GPU [True/False]``: set to ``False`` to disable GPU dependency (defaults to ``True``)
+- ``ALPHAFOLD_AA_LENGTH_MIN``: minimum accepted sequence length (default ``0``)
+- ``ALPHAFOLD_AA_LENGTH_MAX``: maximum accepted sequence length (default ``0`` - no validation)
 
 Closing
 ~~~~~~~