Mercurial > repos > greg > plant_tribes_gene_family_classifier
view gene_family_classifier.py @ 0:f8603464bea7 draft
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author | greg |
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date | Thu, 08 Jun 2017 12:48:23 -0400 |
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children | 3e10a2683769 |
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#!/usr/bin/env python import argparse import os import shutil import utils BUFF_SIZE = 1048576 OUTPUT_DIR = 'geneFamilyClassification_dir' parser = argparse.ArgumentParser() parser.add_argument('--input', dest='input', help='Input dataset') parser.add_argument('--scaffold', dest='scaffold', help='Orthogroups or gene families proteins scaffold') parser.add_argument('--method', dest='method', help='Protein clustering method') parser.add_argument('--classifier', dest='classifier', help='Protein classification method') parser.add_argument('--config_dir', dest='config_dir', help='Directory containing default configuration files') parser.add_argument('--num_threads', dest='num_threads', type=int, help='Number of threads to use for execution') parser.add_argument('--super_orthogroups', dest='super_orthogroups', default=None, help='Super orthogroups clustering specification') parser.add_argument('--single_copy_custom', dest='single_copy_custom', default=None, help='Custom single copy orthogroup configuration') parser.add_argument('--single_copy_taxa', dest='single_copy_taxa', type=int, default=0, help='Minimum single copy taxa required in orthogroup') parser.add_argument('--taxa_present', dest='taxa_present', type=int, default=0, help='Minimum taxa required in single copy orthogroup') parser.add_argument('--orthogroup_fasta', dest='orthogroup_fasta', default=None, help='Flag to create orthogroup sequences') parser.add_argument('--coding_sequences', dest='coding_sequences', default=None, help='Flag to create orthogroup coding sequences') parser.add_argument('--save_hmmscan_log', dest='save_hmmscan_log', default=None, help='Flag to save the hmmscan log') parser.add_argument('--hmmscan_log', dest='hmmscan_log', default=None, help='hmmscan log file') parser.add_argument('--output_ptortho', dest='output_ptortho', default=None, help='Output for orthogroups') parser.add_argument('--output_ptortho_dir', dest='output_ptortho_dir', default=None, help='output_ptortho.files_path') parser.add_argument('--output_ptorthocs', dest='output_ptorthocs', default=None, help='Output for orthogroups with corresponding coding sequences') parser.add_argument('--output_ptorthocs_dir', dest='output_ptorthocs_dir', default=None, help='output_ptorthocs.files_path') parser.add_argument('--output_ptsco', dest='output_ptsco', default=None, help='Output for single copy orthogroups') parser.add_argument('--output_ptsco_dir', dest='output_ptsco_dir', default=None, help='output_ptsco.files_path') args = parser.parse_args() # Build the command line. cmd = 'GeneFamilyClassifier' cmd += ' --proteins %s' % args.input cmd += ' --scaffold %s' % args.scaffold cmd += ' --method %s' % args.method cmd += ' --classifier %s' % args.classifier cmd += ' --config_dir %s' % args.config_dir cmd += ' --num_threads %d' % args.num_threads if args.super_orthogroups is not None: cmd += ' --super_orthogroups %s' % args.super_orthogroups if args.single_copy_custom is not None: cmd += ' --single_copy_custom %s' % args.single_copy_custom if args.single_copy_taxa > 0: cmd += ' --single_copy_taxa %d' % args.single_copy_taxa if args.taxa_present > 0: cmd += ' --taxa_present %d' % args.taxa_present if args.orthogroup_fasta is None: create_ortho_sequences = False else: create_ortho_sequences = True cmd += ' --orthogroup_fasta' if args.coding_sequences is None: create_corresponding_coding_sequences = False else: create_corresponding_coding_sequences = True cmd += ' --coding_sequences %s' % args.coding_sequences # Run the command. utils.run_command(cmd) # Handle hmmscan.log output. if args.classifier in ['hmmscan', 'both']: src_hmmscan_log = os.path.join(OUTPUT_DIR, 'hmmscan.log') if os.path.exists(src_hmmscan_log): if args.save_hmmscan_log is None: os.remove(src_hmmscan_log) else: shutil.move(src_hmmscan_log, args.hmmscan_log) # Handle orthogroups outputs. if create_ortho_sequences: if create_corresponding_coding_sequences: out_file = args.output_ptorthocs orthogroups_fasta_dest_dir = args.output_ptorthocs_dir title = 'Orthogroups and corresponding coding sequences files' else: out_file = args.output_ptortho orthogroups_fasta_dest_dir = args.output_ptortho_dir title = 'Orthogroups files' orthogroups_fasta_src_dir = os.path.join(OUTPUT_DIR, 'orthogroups_fasta') utils.move_directory_files(orthogroups_fasta_src_dir, orthogroups_fasta_dest_dir) utils.write_html_output(out_file, title, orthogroups_fasta_dest_dir) # Handle single copy orthogroup outputs. if args.output_ptsco is not None: single_copy_fasta_src_dir = os.path.join(OUTPUT_DIR, 'single_copy_fasta') single_copy_fasta_dest_dir = args.output_ptsco_dir title = 'Single copy orthogroups files' utils.move_directory_files(single_copy_fasta_src_dir, single_copy_fasta_dest_dir) utils.write_html_output(args.output_ptsco, title, single_copy_fasta_dest_dir)