view test-data/create/sequences.ffdata @ 2:81c7d4668a7e draft

"planemo upload commit bd03b7888eab0b010acfc3affd38bf4d4e2bb1ef-dirty"
author guerler
date Wed, 16 Dec 2020 12:02:48 +0000
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Query         NP_000282.1
Match_columns 417
No_of_seqs    604 out of 4515
Neff          6.98956
Searched_HMMs 787
Date          Fri Jul 24 20:35:21 2020
Command       /home/guerler/hh-suite/build/bin/hhblits -i /home/guerler/human/fasta/NP_00/NP_000282.1.fasta -d /home/guerler/pdb70/pdb70 -o /home/guerler/human/hhr/NP_00/NP_000282.1.hhr 

 No Hit                             Prob E-value P-value  Score    SS Cols Query HMM  Template HMM
  1 2WZB_A PHOSPHOGLYCERATE KINASE 100.0  9E-114  7E-118  875.1   0.0  415    3-417     2-416 (416)
  2 1HDI_A PHOSPHOGLYCERATE KINASE 100.0  4E-113  3E-117  868.7   0.0  412    6-417     2-413 (413)
  3 6Y3A_A Phosphoglycerate kinase 100.0  3E-112  2E-116  865.4   0.0  414    2-416     9-423 (424)
  4 3UWD_A Phosphoglycerate kinase 100.0  7E-112  6E-116  855.6   0.0  391    4-416     1-393 (394)
  5 1QPG_A 3-PHOSPHOGLYCERATE KINA 100.0  7E-112  6E-116  861.3   0.0  413    2-416     1-413 (415)
  6 3PGK_A PHOSPHOGLYCERATE KINASE 100.0  8E-112  7E-116  861.3   0.0  413    2-416     2-414 (416)
  7 3Q3V_A Phosphoglycerate kinase 100.0  3E-111  3E-115  852.3   0.0  392    2-416     3-399 (403)
  8 1PHP_A 3-PHOSPHOGLYCERATE KINA 100.0  1E-110  9E-115  847.6   0.0  387    8-416     5-393 (394)
  9 1VPE_A PHOSPHOGLYCERATE KINASE 100.0  1E-110  1E-114  848.4   0.0  392    6-416     2-395 (398)
 10 4FEY_A Phosphoglycerate kinase 100.0  6E-110  5E-114  842.0   0.0  388    2-416     2-391 (395)
 11 1V6S_B Phosphoglycerate kinase 100.0  1E-109  1E-113  838.8   0.0  386    7-416     2-390 (390)
 12 3ZLB_A PHOSPHOGLYCERATE KINASE 100.0  2E-109  1E-113  840.0   0.0  394    4-416     1-397 (398)
 13 4EHJ_A Phosphoglycerate kinase 100.0  2E-109  2E-113  837.1   0.0  386    4-416     1-388 (392)
 14 16PK_A 3-PHOSPHOGLYCERATE KINA 100.0  4E-109  4E-113  840.3   0.0  395    6-416     2-414 (415)
 15 3OZ7_B Phosphoglycerate kinase 100.0  4E-109  4E-113  840.5   0.0  413    3-416     4-417 (417)
 16 4DG5_A Phosphoglycerate kinase 100.0  5E-109  4E-113  836.1   0.0  392    5-416     9-402 (403)
 17 6HXE_A Phosphoglycerate kinase 100.0  4E-108  4E-112  826.1   0.0  381    4-416     1-383 (387)
 18 4NG4_B Phosphoglycerate kinase 100.0  5E-108  4E-112  830.0   0.0  389    1-416     9-399 (404)
 19 4NG4_C Phosphoglycerate kinase 100.0  5E-108  4E-112  830.0   0.0  389    1-416     9-399 (404)
 20 6I06_A Phosphoglycerate kinase 100.0  1E-107  9E-112  823.4   0.0  381    4-416     1-383 (387)
 21 2CUN_A Phosphoglycerate kinase 100.0  3E-105  3E-109  811.0   0.0  387    8-416     3-400 (410)
 22 1FW8_A PHOSPHOGLYCERATE KINASE 100.0 8.8E-90 7.6E-94  698.3   0.0  342   74-416     2-343 (416)
 23 1FW8_A PHOSPHOGLYCERATE KINASE  99.3 3.2E-16 2.7E-20  156.7   0.0   68    3-70    347-414 (416)
 24 2Q33_B D-MONELLIN CHAIN A, D-M  34.3     5.9 0.00042   24.6   0.0   11  310-320     2-12  (48)

No 1
>2WZB_A PHOSPHOGLYCERATE KINASE 1 (E.C.2.7.2.3); HEREDITARY HEMOLYTIC ANEMIA, TRANSFERASE, PHOSPHOPROTEIN; HET: ADP, 3PG; 1.47A {HOMO SAPIENS}
Probab=100.00  E-value=8.6e-114  Score=875.06  Aligned_cols=415  Identities=100%  Similarity=1.449  Sum_probs=363.4  Template_Neff=6.400

Q NP_000282.1       3 LSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVA   82 (417)
Q Consensus         3 ~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va   82 (417)
                      +..|++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++..++.+||+||+
T Consensus         2 ~~~~~~l~~~~l~gK~vlvR~D~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGrP~g~~~~~~~Sl~pv~   81 (416)
T 2WZB_A            2 LSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVA   81 (416)
T ss_dssp             CTTBCBGGGCCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTCSEEEEECCCSCCTTSCCHHHHCSHHHH
T ss_pred             CcccccccccccCCCEEEEEeEccccccCCccCCChHHHHHHHHHHHHHHCCCCEEEEEeeCCCCCCCCCCcccChHHHH
Confidence            45788898889999999999999999998899999999999999999999999448999999999875323479999999


Q NP_000282.1      83 VELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYV  162 (417)
Q Consensus        83 ~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyV  162 (417)
                      ++|+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|+++++++++|+.+++.+++.+|+++||+++|+||
T Consensus        82 ~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~~~~n~~k~~~~~~~~fa~~La~l~DiyV  161 (416)
T 2WZB_A           82 VELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYV  161 (416)
T ss_dssp             HHHHHHHTSCCEECSCSSSHHHHHHHHSCCTTEEEECCCGGGSHHHHTCC----------CHHHHHHHHHHHHHTCSEEE
T ss_pred             HHHHHHhCCEEEEcccCCCHHHHHHHhCCCCCcEEEEeccccchhhcCCCCCCCCccccCCHHHHHHHHHHHhcccceEE
Confidence            99999998779999999998888888899999999999999998776331111111111112234679999999999999


Q NP_000282.1     163 NDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF  242 (417)
Q Consensus       163 NDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~  242 (417)
                      |||||++||.|||++++++|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+|||
T Consensus       162 NDAF~~~HR~hAS~vgi~lp~s~aG~ll~kEl~~L~~~~~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~IligG~~a~  241 (416)
T 2WZB_A          162 NDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF  241 (416)
T ss_dssp             ECCGGGTTCCCHHHHCCCCSCEEECHHHHHHHHHHHHHHHSCCSSEEEEECSSCHHHHGGGHHHHTTTCSEEEECGGGHH
T ss_pred             ecccccCCCccccccccCCCccchHHHHHHHHHHHHHHhcCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEeCcHHHH
Confidence            99999999999999999976589999999999999999999999999999999999999999999998999999999999


Q NP_000282.1     243 TFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSK  322 (417)
Q Consensus       243 tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~  322 (417)
                      +||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+..+.....+.....+|++|+++||||+|++
T Consensus       242 tfL~a~~~~~ig~S~~e~~~~~~a~~il~~a~~~~~kI~LP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~  321 (416)
T 2WZB_A          242 TFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSK  321 (416)
T ss_dssp             HHHHHHHCCCCTTSCCCHHHHTTHHHHHHHHHHTTCEEECCCEEEEESSSSTTCCEEEEETTTCCCTTCEEEEECHHHHH
T ss_pred             HHHHHhCCCccccceecchHHHHHHHHHHHHHHcCCEEEceeeEEecccccccccCCeeeecCCCCCCceeecCCHHHHH
Confidence            99999856689999999999999999999988999999999999999865332211111112378899999999999999


Q NP_000282.1     323 KYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLEL  402 (417)
Q Consensus       323 ~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~  402 (417)
                      .|+++|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+|||
T Consensus       322 ~~~~~I~~aktI~wNGP~G~~E~~~f~~GT~~ia~al~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~L~~  401 (416)
T 2WZB_A          322 KYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLEL  401 (416)
T ss_dssp             HHHHHHHHCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEEESTTHHHHHHHTTCTTSSSEEESCSHHHHHH
T ss_pred             HHHHHHHhCCEEEEcCCCCcccchhhchHHHHHHHHHHHHhcCCcEEEEecccHHHHHHHcCCCccCeEEecCcHHHHHH
Confidence            99999999999999999999998889999999999997632247899999999999998889888899999999999999


Q NP_000282.1     403 LEGKVLPGVDALSNI  417 (417)
Q Consensus       403 L~G~~LPgl~aL~~~  417 (417)
                      |+|++||||++|+++
T Consensus       402 L~G~~LPgieaL~~~  416 (416)
T 2WZB_A          402 LEGKVLPGVDALSNI  416 (416)
T ss_dssp             HHTCCCHHHHTSCBC
T ss_pred             HcCCCCchHHHHhcC
Confidence            999999999999875


No 2
>1HDI_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); PHOSPHOTRANSFERASE, KINASE, PHOSPHOGLYCERATE, TERNARY COMPLEX; HET: AMP, 3PG; 1.8A {SUS SCROFA} SCOP: c.86.1.1
Probab=100.00  E-value=4.1e-113  Score=868.67  Aligned_cols=412  Identities=91%  Similarity=1.360  Sum_probs=361.3  Template_Neff=6.300

Q NP_000282.1       6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVEL   85 (417)
Q Consensus         6 ~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L   85 (417)
                      +++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++..++.+||+||+++|
T Consensus         2 ~~~l~~~~l~gK~vlvR~D~NVPi~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGRP~g~~~~~~~Sl~pva~~L   81 (413)
T 1HDI_A            2 KLTLDKLNVKGKRVVMRVDFNVPMAAAQITNNARIKAAVPSIKFCLDDGAKSVVLMSHLGRPDGSPMPDKYSLQPVAAEL   81 (413)
T ss_dssp             BCBGGGSCCTTCEEEEECCCCCCBSSSSBSCCHHHHHHHHHHHHHHHTTCSEEEEECCCSCCCSSCCTTTSCSHHHHHHH
T ss_pred             CccccccccCCCEEEEEeecCccccccccCCChHHHHHHHHHHHHHHCCCCEEEEEeeCCCCCCCCCCcccccHHHHHHH
Confidence            56777788999999999999999988899999999999999999999999448999999999875323479999999999


Q NP_000282.1      86 KSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDA  165 (417)
Q Consensus        86 ~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDA  165 (417)
                      +++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++++++++|+.+.+.+++.+|++.||+++|+|||||
T Consensus        82 ~~~l~~~V~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~~~~n~~~~~~~~~~~fa~~La~l~DiyVnDA  161 (413)
T 1HDI_A           82 KSALGKAVLFLKDCVGPAVEKACADPAAGSVILLENLRFHVEEEGKGKDASGNKAAGEPAKIKAFRASLSALGDVYVNDA  161 (413)
T ss_dssp             HHHHTSCCEECSCSSSHHHHHHHHSCCTTEEEECCCGGGSHHHHTEEECTTSCEEECCHHHHHHHHHHHHHTCSEEEECC
T ss_pred             HHHhCCEEEEccccCCHHHHHHhhCCCCCCEEEeeccccchhhcCCCCCCCcccccCCHHHHHHHHHHHHhccccEeecc
Confidence            99998779999999998888888999999999999999999776331100011101111224679999999999999999


Q NP_000282.1     166 FGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFL  245 (417)
Q Consensus       166 Fg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~tfl  245 (417)
                      |+++||.|||++++++|+++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+++||.|++||+|||+||
T Consensus       162 F~~~HR~hAS~vgi~lp~~~aG~l~~kEi~~L~~~~~~p~rP~v~IlGGaKv~dKi~li~~Ll~~~D~IliGG~~a~tFL  241 (413)
T 1HDI_A          162 FGTAHRAHSSMVGVNLPKKAGAFLMKKELNYFAAAAESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFL  241 (413)
T ss_dssp             GGGTTCCCHHHHCCCCSCEEECHHHHHHHHHHHHHHTSCCSSEEEEECCSCSGGGHHHHHHHHTTCSEEEECGGGHHHHC
T ss_pred             cccCCCCCCCccccCCchhHHHHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHcCCEEEECchHHHHHH
Confidence            99999999999999986579999999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     246 KVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYA  325 (417)
Q Consensus       246 ~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~~~  325 (417)
                      +|++++++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+..+...........+|++|+++||||+|++.|+
T Consensus       242 ~a~g~~~iG~Sl~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~~~~~~~~~ip~~~~ilDIGp~Ti~~~~  321 (413)
T 1HDI_A          242 KVLNNMEIGTSLFDEAGKKIVKNLMSKAAANGVKITLPVDFVTADKFDEQAKIGQATVASGIPAGWMGLDCGPKSSAKYS  321 (413)
T ss_dssp             CCCCCCCBTTCCCCTTGGGTHHHHHHHHHHHTCEEECCCEEEEESSSSTTCCEEEEETTTCBCTTCEEEEECHHHHHHHH
T ss_pred             HHhCCCcccceeechhHHHHHHHHHHHHHHCCCeEEceeeEEeccccchhcccceeeecCCCCCCcccccCCHHHHHHHH
Confidence            99855689999999999999999999988999999999999999875432211111112378899999999999999999


Q NP_000282.1     326 EAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEG  405 (417)
Q Consensus       326 ~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L~G  405 (417)
                      ++|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||||+|
T Consensus       322 ~~I~~aktI~wnGP~G~~E~~~f~~GT~~ia~~i~~~~~~~a~sivGGGdT~~~~~~~g~~~~~~~vSTGGGA~Le~L~g  401 (413)
T 1HDI_A          322 EAVARAKQIVWNGPVGVFEWEAFAQGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDNVSHVSTGGGASLELLEG  401 (413)
T ss_dssp             HHHHHCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEECTTHHHHHHHHTTCTTTSSEECSCHHHHHHHHTT
T ss_pred             HHHHhCCEEEEeCCCCcccchhhchHHHHHHHHHHHHhcCCcEEEEecccHHHHHHHcCCCCCCEEEecChHHHHHHHcC
Confidence            99999999999999999988789999999999997632247899999999999888888888899999999999999999


Q NP_000282.1     406 KVLPGVDALSNI  417 (417)
Q Consensus       406 ~~LPgl~aL~~~  417 (417)
                      +.||||++|+++
T Consensus       402 k~LPgi~aL~~~  413 (413)
T 1HDI_A          402 KVLPGVDALSNV  413 (413)
T ss_dssp             CCCHHHHTSCBC
T ss_pred             CCCchHHHhhcC
Confidence            999999999874


No 3
>6Y3A_A Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, metabolic enzyme, kinase; 1.49A {Plasmodium vivax}
Probab=100.00  E-value=2.6e-112  Score=865.36  Aligned_cols=414  Identities=59%  Similarity=0.970  Sum_probs=363.7  Template_Neff=6.300

Q NP_000282.1       2 SLSNKLTLDKL-DVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         2 ~~~~~~~i~~~-~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      ++.+++++.|. |++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. .+++||+|
T Consensus         9 ~~~~~~~~~~~~~l~gK~vlvRvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGRP~g~~-~~~~Sl~p   87 (424)
T 6Y3A_A            9 SLGNKLSITDVKAIQGKKVLVRVDFNVPIENGVIKDTNRITATLPTIHHLKKEGAAKIILISHCGRPDGTK-NLKYTLKP   87 (424)
T ss_dssp             CCTTBCBGGGCCCCTTCEEEEECCCCCCEETTEESCCHHHHTTHHHHHHHHHTTCSEEEEECCCSCCTTSC-CGGGCSHH
T ss_pred             cCCCCccccchHHhCCCEEEEEeecCCcccCCccCCChHHHhHHHHHHHHHHCCCCEEEEEeeCCCCCCCc-cccccHHH
Confidence            46788999997 89999999999999999888999999999999999999999994499999999998764 56899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++++++++|+.++..+++.+|+++||+++|+
T Consensus        88 va~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~~~~n~~~~~~~~~~~fa~~LA~l~Di  167 (424)
T 6Y3A_A           88 VAETLGTLLGEEVLFLSDCVGEEVAAQINQAKDNSVILLENLRFHVEEEGKGVDAAGNKIKASKEDMEKFQNELTKLGDV  167 (424)
T ss_dssp             HHHHHHHHHTSCCEECSCSSSHHHHHHHHHSCTTEEEECCCGGGSHHHHSEEECTTSCEEECCHHHHHHHHHHHHTTCSE
T ss_pred             HHHHHHHHhCCEEEeccccCCHHHHHHHHhccCCCEEEeccccccchhccCCccccccccccCHHHHHHHHHHHhhccCe
Confidence            99999999987799999999988888889999999999999999987753211101121111122346799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM  240 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~  240 (417)
                      |||||||++||.|||+++++.+.++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+|
T Consensus       168 yVNDAF~~~HR~hAS~vgi~~~~s~aG~llekEl~~L~k~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~vD~IligG~~  247 (424)
T 6Y3A_A          168 FINDAFGTAHRAHSSMVGIKMNVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDKMIIGGGM  247 (424)
T ss_dssp             EEECCGGGTTSCCHHHHCCCCSCEEECHHHHHHHHHHHHHHTSCCSSEEEEEECSCSGGGHHHHHHHHTTCSEEEEESTH
T ss_pred             EEecccccCccccCcchHHhccHHHhcHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHcCCEEEECcHH
Confidence            99999999999999999999322899999999999999999999999999999999999999999999989999999999


Q NP_000282.1     241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPES  320 (417)
Q Consensus       241 a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~T  320 (417)
                      ||+||+|++++++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+..+.....+.....+|++|+++||||+|
T Consensus       248 a~tfL~a~~~~~ig~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~T  327 (424)
T 6Y3A_A          248 AYTFKYVLNNMKIGDSLFDEAGSKIVNEIMEKAKAKNVEIYLPVDFKVADKFDNNANTKVVTDEEGIEDKWMGLDAGPKS  327 (424)
T ss_dssp             HHHHHHHHHCCCBTTSCCCHHHHTTHHHHHHHHHHTTCEEECCSEEEEESSSSTTSCEEEEETTTCBCTTCEEEEECHHH
T ss_pred             HHHHHHHHCCCcccchhccchhHHHHHHHHHHHHHCCCeEEeeeeeeeccccCCCCCceEecCccCCCCCcccccCCHHH
Confidence            99999997455799999999889999999999989999999999999998753322111122224788999999999999


Q NP_000282.1     321 SKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASL  400 (417)
Q Consensus       321 i~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~L  400 (417)
                      ++.|.+.|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+|
T Consensus       328 i~~~~~~I~~aktI~wNGP~G~~E~e~f~~GT~~ia~al~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~L  407 (424)
T 6Y3A_A          328 IENYKDVILSSKTIIWNGPQGVFEMPNFAKGSIECLNLVIEATKKGAISIVGGGDTASLVEQQQKKNEISHVSTGGGASL  407 (424)
T ss_dssp             HHHHHHHHHTCSEEEEESCSBCTTSGGGCHHHHHHHHHHHHHHHTTCEEEECSHHHHHHHHHTTCGGGSSEECCCTHHHH
T ss_pred             HHHHHHHHHhCCEEEEeCCCCcccCCCcchhHHHHHHHHHHHhcCCCEEEEechHHHHHHHHhccccCcEEEEechhHHH
Confidence            99999999999999999999999988899999999999976322478999999999999988888788999999999999


Q NP_000282.1     401 ELLEGKVLPGVDALSN  416 (417)
Q Consensus       401 e~L~G~~LPgl~aL~~  416 (417)
                      |||+|+.||||++|++
T Consensus       408 e~L~G~~LPgieaL~~  423 (424)
T 6Y3A_A          408 ELLEGKELPGVVALSS  423 (424)
T ss_dssp             HHHTTCCCHHHHTSCB
T ss_pred             HHHcCCCCChhHHhhc
Confidence            9999999999999975


No 4
>3UWD_A Phosphoglycerate kinase (E.C.2.7.2.3); Anthrax, Structural Genomics, Center for; HET: BTB, MSE; 1.68A {Bacillus anthracis}
Probab=100.00  E-value=6.9e-112  Score=855.65  Aligned_cols=391  Identities=48%  Similarity=0.845  Sum_probs=357.0  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++. .+.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vlvR~D~NVPi~~~~i~dd~RI~~~lpTI~~L~~~ga-kvil~sHlGrP~g~~-~~~~sl~~va~   78 (394)
T 3UWD_A            1 MNKKSIRDVDLKGKRVFCRVDFNVPMKEGKITDETRIRAALPTIQYLVEQGA-KVILASHLGRPKGQA-VEELRLTPVAA   78 (394)
T ss_dssp             CCBCBGGGSCCTTCEEEEECCCCCCC--CCCCCCHHHHHTHHHHHHHHHTTC-EEEEECCCSCCTTSC-CGGGCSHHHHH
T ss_pred             CCCccccccccCCCEEEEEeecCccccCCCcCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCcc-chhhChHHHHH
Confidence            4567888888999999999999999987899999999999999999999999 599999999999864 56899999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+|||
T Consensus        79 ~L~~~l~~~v~f~~~~~g~~~~~~i~~~~~g~i~lLENlRf~~~E~~n---------------d~~fa~~La~l~DiyVn  143 (394)
T 3UWD_A           79 RLGELLGKDVKKADEAFGPVAQEMVAAMNEGDVLVLENVRFYAGEEKN---------------DAELAKEFAALADIFVN  143 (394)
T ss_dssp             HHHHHHTSCCEECSCSSSHHHHHHHHTCCTTCEEECCCGGGSHHHHHT---------------CHHHHHHHHTTCSEEEE
T ss_pred             HHHHHHCCEEeecCccccHHHHHHHHHccCCCEEEEecccccCccccc---------------cHHHHHHHHHhccHHHh
Confidence            999999877999999999888888899999999999999999876532               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      ||||++||.|||+++++  +| ++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       144 DAF~~~HR~hAS~~gi~~~lp-s~aG~ll~kEl~~L~~~~~~p~~P~v~IlGGaKv~dKi~~i~~Ll~~~d~iligG~~a  222 (394)
T 3UWD_A          144 DAFGAAHRAHASTAGIADYLP-AVSGLLMEKELEVLGKALSNPERPFAAIIGGAKVKDKIGLIRHLLDKVDNLIIGGGLA  222 (394)
T ss_dssp             CCGGGTTSCCTTTTGGGGTSC-EEECHHHHHHHHHHHHHHHSCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECSTTH
T ss_pred             ccHhHhcccccchhhHhhhhH-hhhcHHHHHHHHHHHHHHhCCCCCEEEEECCCCHHHHHHHHHHHHHhCCEEEECChHH
Confidence            99999999999999999  77 8999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++...+.. .+...+.+|++|+++||||+|+
T Consensus       223 ~tfL~a~-g~~iG~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DIGp~Ti  300 (394)
T 3UWD_A          223 YTFVKAL-GHEIGLSLCEDDKIELAKEFMQLAKEKGVNFYMPVDVVITEEFSETATT-KIVGIDSIPSNWEGVDIGPKTR  300 (394)
T ss_dssp             HHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHHTCEEECCSEEEEESSCSTTCCE-EEEEGGGCCTTCEEEEECHHHH
T ss_pred             HHHHHHh-CCcccccccchHHHHHHHHHHHHHHHcCCeEEceeeEEeccccCcccce-EEeccccCCCCceeecCCHHHH
Confidence            9999998 8999999999999999999999988899999999999999875432211 1222357889999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|.++|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       301 ~~~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~ai~~~~--~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~Le  378 (394)
T 3UWD_A          301 EIYADVIKNSKLVVWNGPMGVFEMTPFAEGTKAVGQALADAE--GTYSVIGGGDSAAAVEKFGMADKMSHISTGGGASLE  378 (394)
T ss_dssp             HHHHHHHHTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHCT--TCEEEECSHHHHHHHHHTTCGGGCSEECCCTHHHHH
T ss_pred             HHHHHHHhcCCEEEEECCCCcccCCCcChHHHHHHHHHHHcC--CCeEEEechHHHHHHHHcCCCCcceEEEcccHHHHH
Confidence            999999999999999999999988889999999999997632  689999999999888888888889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|++||||++|++
T Consensus       379 ~L~Gk~LPgl~aL~~  393 (394)
T 3UWD_A          379 FMEGKELPGVVCLND  393 (394)
T ss_dssp             HHTTCCCHHHHTSCB
T ss_pred             HHcCCCCCchhhhcc
Confidence            999999999999985


No 5
>1QPG_A 3-PHOSPHOGLYCERATE KINASE, MAGNESIUM-5'-ADENYLY-IMIDO-TRIPHOSPHATE, 3-PHOSPHOGLYCERIC ACID; PHOSPHOTRANSFERASE (CARBOXYL ACCEPTOR), KINASE, GLYCOLYSIS; HET: 3PG, MAP; 2.4A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=100.00  E-value=7.2e-112  Score=861.28  Aligned_cols=413  Identities=66%  Similarity=1.036  Sum_probs=363.5  Template_Neff=6.500

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      +..++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. ++.+||+||
T Consensus         1 ~~~~~~~i~~~~l~gK~vlvRvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGrP~g~~-~~~~Sl~pv   79 (415)
T 1QPG_A            1 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGQPNGER-NEKYSLAPV   79 (415)
T ss_dssp             CTTSBCBGGGCCCTTCEEEEECCCCCCBSSSSBSCCHHHHHHHHHHHHHHTTCCSEEEEECCCSCCCSSC-CGGGCSHHH
T ss_pred             CCcccccccccccCCCEEEEEEecCCccCCCccCCCHHHHHHHHHHHHHHHcCCCEEEEEeeCCCCCCCc-CcccchHHH
Confidence            3567889998999999999999999999888999999999999999999999994489999999998764 568999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++.++ ++.+.+++.+++.+|+++||+++|+|
T Consensus        80 a~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~-n~~~~~~~~~~~~~fa~~LA~l~Diy  158 (415)
T 1QPG_A           80 AKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV-DGQKVKASKEDVQKFRHELSSLADVY  158 (415)
T ss_dssp             HHHHHHHHTSCCEEESCSSSHHHHHHHHTCCTTEEEEECCGGGSHHHHTEEEE-TTEEEECCHHHHHHHHHHHHHTCSEE
T ss_pred             HHHHHHHhCCeEEEccCCCCHHHHHHHHhCCCCCeEehhhhhhcchhcccccc-CCccccCCHHHHHHHHHHHHhcCCeE
Confidence            99999999877999999999888888899999999999999999877532000 00000111223478999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      ||||||++||.|||++++++|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       159 VNDAF~~~HR~hAS~vgi~lp~s~aG~ll~kEl~~L~k~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~IligG~~a  238 (415)
T 1QPG_A          159 INDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMA  238 (415)
T ss_dssp             EECCGGGTTSCCHHHHCCCCSCEEECHHHHHHHHHHHHHHSSCCSSEEEEECSSCSGGGHHHHHHHTTTCSEEEECGGGH
T ss_pred             eecccccCCcccccceecCCChhhhcHHHHHHHHHHHHHhhCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEECcHHH
Confidence            99999999999999999997658999999999999999999999999999999999999999999999899999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+..+.....+...+.+|++|+++||||+|+
T Consensus       239 ~tfL~a~~~~~iG~S~~e~~~~~~a~~il~~a~~~~~ki~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  318 (415)
T 1QPG_A          239 FTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPESR  318 (415)
T ss_dssp             HHHHHHHSCCCCCSCCCCHHHHHHHHHHHHHHHHHTCEEECCSEEEEESSSSSSCCCCEEETTTCCCTTCEEEEECHHHH
T ss_pred             HHHHHHhCCCcCCccccchhhhhHHHHHHHHHHHcCCeEEeeeeEEEecccCCCCCCceeeccCCCCCCCcccccCHHHH
Confidence            99999975558999999998889999999998899999999999999886532221111112237889999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|.+.|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||
T Consensus       319 ~~~~~~i~~aktI~wnGP~G~~E~~~f~~GT~~ia~~i~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTgGGA~L~  398 (415)
T 1QPG_A          319 KLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLE  398 (415)
T ss_dssp             HHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHHTCEEEECCHHHHHHHHHTTCGGGSSEECCCTHHHHH
T ss_pred             HHHHHHHHcCCEEEEcCCCChhcccccChHHHHHHHHHHHHhcCCCeEEEEehHHHHHHHHcCCCCccEEEEcCchHHHH
Confidence            99999999999999999999999888999999999999763224789999999999999888987889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       399 ~L~G~~LPgieaL~~  413 (415)
T 1QPG_A          399 LLEGKELPGVAFLSE  413 (415)
T ss_dssp             HHTSCCCHHHHTSCB
T ss_pred             HHcCCCCChHHHHhh
Confidence            999999999999975


No 6
>3PGK_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); PHOSPHOTRANSFERASE(CARBOXYL AS ACCEPTOR), TRANSFERASE; HET: ATP, 3PG; 2.5A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=100.00  E-value=7.8e-112  Score=861.30  Aligned_cols=413  Identities=64%  Similarity=1.016  Sum_probs=363.8  Template_Neff=6.500

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      +..++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. ++.+||+||
T Consensus         2 ~~~~~~~~~~~~l~gK~vlvRvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~gak~vil~sHlGRP~g~~-~~~~Sl~pv   80 (416)
T 3PGK_A            2 SLSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGER-NEKYSLAPV   80 (416)
T ss_dssp             CCCCSCCSSCCCCSSCCEEEECCCCCCCSSSCCSCCHHHHHHHHHHHHHHHHCCSCCEEECCCCCCCSSS-SCSCCSHHH
T ss_pred             CCcccccccccccCCCEEEEEEecCCccCCCccCCCHHHHHHHHHHHHHHHcCCCEEEEEeecCCCCCCc-CcccChHHH
Confidence            5678899999999999999999999999888999999999999999999999994489999999998764 568999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++.++ ++.+.+++.+++.+|++.||+++|+|
T Consensus        81 a~~L~~~l~~~v~f~~d~~g~~~~~~i~~~~~g~i~lLENlRF~~~E~~~~~~-n~~~~~~~~~~~~~fa~~La~l~diy  159 (416)
T 3PGK_A           81 AKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV-DGQKVKASKEDVQKFRHELSSLADVY  159 (416)
T ss_dssp             HHHHHHHHCSCEECCCSSCCHHHHHHHHHSSSCEEEECSSCSSCSSCCCCSSS-SSSSCCCCCHHHHHHHHHHHTSCSEE
T ss_pred             HHHHHHHHCCeeEEcccCCCHHHHHHHHhCCCCCeEehhhhhhcchhcccccc-CCcccccCHHHHHHHHHHHHhcCCeE
Confidence            99999999877999999999888888899999999999999999877522000 00001111223477999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      ||||||++||.|||++++++|+++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       160 VNDAF~~~HR~hAS~vgi~lp~s~aG~ll~kEl~~L~k~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~a  239 (416)
T 3PGK_A          160 INDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDSIIIGGGMA  239 (416)
T ss_dssp             EECSSCSSSSCCTTSSSCCSSCEEECHHHHHHHHHHHHHTSCCSSCBEEEECSSCCSTHHHHHHHHHSSSSCEEEECCHH
T ss_pred             eecccccCCccccCccccCCchhhhcHHHHHHHHHHHHHhhCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEeCcHHH
Confidence            99999999999999999997658999999999999999999999999999999999999999999999899999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+........+...+.+|++|+++||||+|+
T Consensus       240 ~tfL~a~~~~~iG~s~~e~~~~~~a~~il~~a~~~~~kI~LP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  319 (416)
T 3PGK_A          240 FTFKKVLENTEIGDSIFDKAVGPEIAKLMEKAKAKGVEVVLPVDFIIADAFSASANTKTVTDKEGIPAGWQGLDNGPESR  319 (416)
T ss_dssp             HHHHHSSHHHHHHCSCSCTTHHHHHHHHHHHHHHHTCEECCCSEEEECSSSSSSSCEEEESSCCSSSCSSCCCSCCHHHH
T ss_pred             HHHHHHhCCCccCcchhcccchHHHHHHHHHHHHcCCeEEccccEEEeccccccCCcceeecccCCCCCCccccCCHHHH
Confidence            99999975568999999998889999999988889999999999999886532221111112237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|.+.|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||
T Consensus       320 ~~~~~~i~~aktI~wnGP~G~~E~~~f~~GT~~ia~~i~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~L~  399 (416)
T 3PGK_A          320 KLFAATVAKATVILWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVSTGGGASLE  399 (416)
T ss_dssp             HHHHHHHSSCSBEEECSCSSCTTSTTSSSHHHHHHHHHHHHTTSSCCEEECSSHHHHHHHHHCCTTCCEECCCSHHHHHH
T ss_pred             HHHHHHHHhCCEEEEeCCCChhhccccchHHHHHHHHHHHHccCCCeEEEEehhHHHHHHHcCCCCcceEEecChhHHHH
Confidence            99999999999999999999999888999999999999763224789999999999999888987889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       400 ~L~Gk~LPgl~aL~~  414 (416)
T 3PGK_A          400 LLEGKELPGVAFLSE  414 (416)
T ss_dssp             HHHTCCCHHHHHCSS
T ss_pred             HHcCCCCChHHHHhc
Confidence            999999999999975


No 7
>3Q3V_A Phosphoglycerate kinase (E.C.2.7.2.3); Structural Genomics, Center for Structural; HET: SO4, FMT, PGE; 2.145A {Campylobacter jejuni subsp. jejuni NCTC 11168}
Probab=100.00  E-value=3.2e-111  Score=852.34  Aligned_cols=392  Identities=45%  Similarity=0.820  Sum_probs=356.7  Template_Neff=6.300

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKN-NQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~-~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      +|+++++++|.|++|||||||+|+|||+++ ++|.|++||++++|||+||+++|| +|||+||+|||+++  ++.+||+|
T Consensus         3 ~~~~~~~l~~~~l~gK~vlvR~D~NVPi~~~~~i~dd~RI~~~lpTI~~Ll~~ga-~vil~sHlGrP~~~--~~~~Sl~~   79 (403)
T 3Q3V_A            3 AMSDIISIKDIDLAKKKVFIRCDFNVPQDDFLNITDDRRIRSAIPTIRYCLDNGC-SVILASHLGRPKEI--SSKYSLEP   79 (403)
T ss_dssp             ---CBCBGGGSCCTTCEEEEECCCCCCBCTTCCBSCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCSSC--CGGGCSHH
T ss_pred             cccccccccchhcCCCEEEEEeecCCCcccCCccCCChHHHHHHHHHHHHHHCCC-EEEEEecCCCCccc--CcccCHHH
Confidence            578899999889999999999999999975 489999999999999999999999 59999999999865  35899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+
T Consensus        80 va~~L~~~l~~~V~f~~~~~g~~~~~~i~~~~~g~i~lLENlRF~~~E~~n---------------~~~fa~~La~l~Di  144 (403)
T 3Q3V_A           80 VAKRLARLLDKEIVMAKDVIGEDAKTKAMNLKAGEILLLENLRFEKGETKN---------------DENLAKELASMVQV  144 (403)
T ss_dssp             HHHHHHHHHTSCCEECSSSSSHHHHHHHHHCCTTCEEECSCGGGSTTGGGT---------------CHHHHHHHHHTCSE
T ss_pred             HHHHHHHHhCCeeeecCCCCCHHHHHHHHhccCCCEEEEcccccCCcccCC---------------CHHHHHHHHhhchH
Confidence            999999999877999999999888888889999999999999999876422               36799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVN--LPQ--KAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMII  236 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~--l~~--~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~ili  236 (417)
                      |||||||++||.|||+++++  +|+  ++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.|+|
T Consensus       145 yVNDAF~~~HR~hAS~vgi~~~lp~~~s~aG~ll~kEl~~L~~~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~ili  224 (403)
T 3Q3V_A          145 YINDAFGVCHRAHSSVEAITKFFDEKHKGAGFLLQKEIDFASNLIKHPARPFVAVVGGSKVSGKLQALTNLLPKVDKLII  224 (403)
T ss_dssp             EEECCGGGTTSCCTTTTGGGGGSCTTSEEECHHHHHHHHHHHHHTTCCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEE
T ss_pred             HHhcccccccccCcchhHHHhhcccccccccHHHHHHHHHHHHHHhCCCCCEEEEECCCcHHHHHHHHHHHHHhCCEEEE
Confidence            99999999999999999998  663  79999999999999999999999999999999999999999999999999999


Q NP_000282.1     237 GGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDC  316 (417)
Q Consensus       237 gG~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DI  316 (417)
                      ||+|||+||+|+ |+++|+|++|++..+.|++++++|++++++|++|+|++|.+++..++.. ...+...+|++|+++||
T Consensus       225 gG~~a~tfL~a~-g~~iG~s~~e~~~~~~a~~il~~a~~~~~kI~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DI  302 (403)
T 3Q3V_A          225 GGGMAFTFLKAL-GYDIGNSLLEEELLEEANKILTKGKNLGVKIYLPVDVVAAPACSQDVPM-KFVPAQEIPNGWMGLDI  302 (403)
T ss_dssp             CSTTHHHHHHHT-TCCCTTSCCCGGGHHHHHHHHHHHHHTTCEEECCSEEEEESSSSTTSCC-EEEEGGGCCTTCEEEEE
T ss_pred             cchHHHHHHHHc-CCCCccchhhHHHHHHHHHHHHHHHHhCCeeEeeccEEecCcCCCCCCc-eeechhhcCCCccCccC
Confidence            999999999998 8999999999999999999999998999999999999999865322211 11122478889999999


Q NP_000282.1     317 GPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGG  396 (417)
Q Consensus       317 Gp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgG  396 (417)
                      ||+|++.|.+.|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||
T Consensus       303 Gp~Ti~~~~~~i~~aktI~wnGp~G~~E~e~f~~GT~~i~~~i~~~---~a~~ivGGGdT~~~~~~~g~~~~~~~vStGG  379 (403)
T 3Q3V_A          303 GPASVRLFKEVISDAQTIWWNGPMGVFEIDKFSKGSIKMSHYISEG---HATSVVGGGDTADVVARAGDADEMTFISTGG  379 (403)
T ss_dssp             CHHHHHHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHS---SSEEEEESHHHHHHHHHTTCGGGSSEECCCH
T ss_pred             CHHHHHHHHHHHhhCCEEEEeCCCCcccccccchHHHHHHHHHHhC---CCeEEEeCHHHHHHHHHcCCCccccEEecch
Confidence            9999999999999999999999999999878999999999999762   6899999999999999889888899999999


Q NP_000282.1     397 GASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       397 gA~Le~L~G~~LPgl~aL~~  416 (417)
                      ||+||||+|++||||++|++
T Consensus       380 GA~Le~L~Gk~LPgi~aL~~  399 (403)
T 3Q3V_A          380 GASLELIEGKELPGVKALRS  399 (403)
T ss_dssp             HHHHHHHTTCCCHHHHTTBC
T ss_pred             HHHHHHHcCCCCchHHHHhh
Confidence            99999999999999999975


No 8
>1PHP_A 3-PHOSPHOGLYCERATE KINASE (PGK) (E.C.2.7.2.3); KINASE; HET: ADP; 1.65A {Geobacillus stearothermophilus} SCOP: c.86.1.1
Probab=100.00  E-value=1.1e-110  Score=847.59  Aligned_cols=387  Identities=48%  Similarity=0.853  Sum_probs=355.2  Template_Neff=6.500

Q NP_000282.1       8 TLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKS   87 (417)
Q Consensus         8 ~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L~~   87 (417)
                      +++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++. .+.+||+||+++|++
T Consensus         5 ~l~~~~l~gK~vl~R~D~NVpi~~~~i~d~~RI~~~lpTI~~Ll~~ga-kvvl~sHlGrP~g~~-~~~~Sl~~va~~L~~   82 (394)
T 1PHP_A            5 TIRDVDVRGKRVFCRVDFNVPMEQGAITDDTRIRAALPTIRYLIEHGA-KVILASHLGRPKGKV-VEELRLDAVAKRLGE   82 (394)
T ss_dssp             BGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSSC-CGGGCSHHHHHHHHH
T ss_pred             cccccccCCCEEEEEeecCCcccCCCCCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCCc-chhhhHHHHHHHHHH
Confidence            777788999999999999999988899999999999999999999999 599999999998764 468999999999999


Q NP_000282.1      88 LLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFG  167 (417)
Q Consensus        88 ~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDAFg  167 (417)
                      +|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+|||||||
T Consensus        83 ~l~~~v~f~~~~~g~~~~~~i~~~~~g~illLENlRf~~~E~~n---------------~~~fa~~La~l~DiyVnDAF~  147 (394)
T 1PHP_A           83 LLERPVAKTNEAVGDEVKAAVDRLNEGDVLLLENVRFYPGEEKN---------------DPELAKAFAELADLYVNDAFG  147 (394)
T ss_dssp             HHTSCCEECSCSSSHHHHHHHHTCCTTCEEECCCGGGSHHHHHT---------------CHHHHHHHHTTCSEEEECCGG
T ss_pred             HhCCCeeecCCCCCHHHHHHHHhccCCCEEEeecccCCCccccC---------------CHHHHHHHHHhccHHHccchh
Confidence            99877999999999888888899999999999999999866432               367999999999999999999


Q NP_000282.1     168 TAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFTFL  245 (417)
Q Consensus       168 ~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~tfl  245 (417)
                      ++||.|||+++++  +| ++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+|||+||
T Consensus       148 ~~HR~hAS~vgi~~~lp-s~aG~ll~kEl~~L~~~l~~p~rP~v~IlGGaKv~dKi~~i~~ll~~~d~iligG~~a~tfL  226 (394)
T 1PHP_A          148 AAHRAHASTEGIAHYLP-AVAGFLMEKELEVLGKALSNPDRPFTAIIGGAKVKDKIGVIDNLLEKVDNLIIGGGLAYTFV  226 (394)
T ss_dssp             GTTSCCTTTTGGGGTSC-EEECHHHHHHHHHHHHHHHSCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECTTHHHHHH
T ss_pred             HhccccchhhhHHhhhh-hhhcHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHhhcCeEEEcchHHHHHH
Confidence            9999999999999  67 89999999999999999999999999999999999999999999998999999999999999


Q NP_000282.1     246 KVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKKYA  325 (417)
Q Consensus       246 ~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~~~  325 (417)
                      +|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+..++.. ...+.+.+|++|+++||||+|++.|+
T Consensus       227 ~a~-g~~iG~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DIGp~Ti~~~~  304 (394)
T 1PHP_A          227 KAL-GHDVGKSLLEEDKIELAKSFMEKAKEKGVRFYMPVDVVVADRFANDANT-KVVPIDAIPADWSALDIGPKTRELYR  304 (394)
T ss_dssp             HHT-TCCCTTSCCCGGGHHHHHHHHHHHHHHTCEEECCSEEEEESSSSTTSCE-EEEEGGGCCTTCEEEEECHHHHHHHH
T ss_pred             HHh-CCCCCcccccHhHHHHHHHHHHHHHHcCCEEEceeeEEEeccccccCCc-eEeecCcCCCCcccccCCHHHHHHHH
Confidence            998 8999999999999999999999988899999999999998865322211 11122478899999999999999999


Q NP_000282.1     326 EAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELLEG  405 (417)
Q Consensus       326 ~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L~G  405 (417)
                      ++|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++++.++++||||||||+||||+|
T Consensus       305 ~~i~~aktI~wnGP~G~~E~~~f~~GT~~i~~~i~~~~--~a~~viGGGdT~~~~~~~~~~~~~~~vStgGGA~Le~L~G  382 (394)
T 1PHP_A          305 DVIRESKLVVWNGPMGVFEMDAFAHGTKAIAEALAEAL--DTYSVIGGGDSAAAVEKFGLADKMDHISTGGGASLEFMEG  382 (394)
T ss_dssp             HHHHTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHCT--TCEEEECSHHHHHHHHHTTCGGGSSEECSCTHHHHHHHTT
T ss_pred             HHHHhCCEEEEeCCCCccccchhchHHHHHHHHHHHhc--CCcEEEechHHHHHHHHcCCCccCeEEecchhHHHHHHcC
Confidence            99999999999999999998889999999999997632  7899999999998888888877899999999999999999


Q NP_000282.1     406 KVLPGVDALSN  416 (417)
Q Consensus       406 ~~LPgl~aL~~  416 (417)
                      +.||||++|++
T Consensus       383 ~~LPgl~aL~~  393 (394)
T 1PHP_A          383 KQLPGVVALED  393 (394)
T ss_dssp             CCCHHHHTSCB
T ss_pred             CCCChhHHhhc
Confidence            99999999975


No 9
>1VPE_A PHOSPHOGLYCERATE KINASE, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER; TRANSFERASE, PHOSPHOGLYCERATE KINASE, THERMOTOGA MARITIMA; HET: 3PG, ANP; 2.0A {Thermotoga maritima} SCOP: c.86.1.1
Probab=100.00  E-value=1.1e-110  Score=848.42  Aligned_cols=392  Identities=49%  Similarity=0.875  Sum_probs=356.6  Template_Neff=6.500

Q NP_000282.1       6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVEL   85 (417)
Q Consensus         6 ~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L   85 (417)
                      |+++++.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++. ++.+||+||+++|
T Consensus         2 ~~~l~~~~l~gK~vl~R~D~NVP~~~~~i~dd~Ri~~~lpTI~~Ll~~ga-~vil~sHlGrP~g~~-~~~~Sl~~v~~~L   79 (398)
T 1VPE_A            2 KMTIRDVDLKGKRVIMRVDFNVPVKDGVVQDDTRIRAALPTIKYALEQGA-KVILLSHLGRPKGEP-SPEFSLAPVAKRL   79 (398)
T ss_dssp             BCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSSC-CGGGCSHHHHHHH
T ss_pred             CccccccccCCCEEEEEeeCCcccCCCccCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCCC-CcccCHHHHHHHH
Confidence            56777788999999999999999988899999999999999999999999 599999999998764 4689999999999


Q NP_000282.1      86 KSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDA  165 (417)
Q Consensus        86 ~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDA  165 (417)
                      +++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++               +.+|++.||+++|+|||||
T Consensus        80 ~~~l~~~V~f~~~~~g~~~~~~i~~~~~g~i~lLENlRf~~~E~~n---------------~~~fa~~La~l~DiyVnDA  144 (398)
T 1VPE_A           80 SELLGKEVKFVPAVVGDEVKKAVEELKEGEVLLLENTRFHPGETKN---------------DPELAKFWASLADIHVNDA  144 (398)
T ss_dssp             HHHHTSCCEEESCSSSHHHHHHHHTCCTTEEEEECCGGGSTHHHHT---------------CHHHHHHHHTTCSEEEECC
T ss_pred             HHHhCCceeecCCccCHHHHHHHHHhhCCCEEEeeccccCCccccC---------------CHHHHHHHHhcccceeecc
Confidence            9999877999999999888888889999999999999999876422               3679999999999999999


Q NP_000282.1     166 FGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFT  243 (417)
Q Consensus       166 Fg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~t  243 (417)
                      |+++||.|||+++++  +| ++||++|++|+++|.+++++|+||+++|+||+|++||+++|++|++++|.|++||+||++
T Consensus       145 F~~~HR~~aS~vgi~~~lp-s~aG~l~~kEl~~L~~~~~~p~~P~v~IlGGaKv~dKi~~i~~ll~k~d~iligG~la~t  223 (398)
T 1VPE_A          145 FGTAHRAHASNVGIAQFIP-SVAGFLMEKEIKFLSKVTYNPEKPYVVVLGGAKVSDKIGVITNLMEKADRILIGGAMMFT  223 (398)
T ss_dssp             GGGTTSCCTTTTGGGGTSC-EEECHHHHHHHHHHHHHHHCCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECTTTHHH
T ss_pred             hhcCCCCcccchHHHhhch-HhhHHHHHHHHHHHHHHhcCCCCCEEEEEcCCCHHHHHHHHHHHHHHCCEEEECchHHHH
Confidence            999999999999998  66 899999999999999999999999999999999999999999999988999999999999


Q NP_000282.1     244 FLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKK  323 (417)
Q Consensus       244 fl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~  323 (417)
                      ||+|+ |+++|+|++|++..+.|++++++|++++++|+||+|++|.+++..+.....+...+.+|++|+++||||+|++.
T Consensus       224 fl~a~-g~~vG~S~~e~~~~~~a~~il~~a~~~~~kI~lP~D~vv~~~~~~~~~~~~~~~~~~ip~~~~i~DIGp~Ti~~  302 (398)
T 1VPE_A          224 FLKAL-GKEVGSSRVEEDKIDLAKELVEKAKEKGVEIVLPVDAVIAQKIEPGVEKKVVRIDDGIPEGWMGLDIGPETIEL  302 (398)
T ss_dssp             HHHHT-SCCCTTSCCCGGGHHHHHHHHHHHHHTTCEEECCSEEEEESSCSTTCCCEEEETTTCCCTTCEEEEECHHHHHH
T ss_pred             HHHHh-CCCccCCcccHHHHHHHHHHHHHHHHcCCEEEceeeeEeccCCCCCCcceEEecccCCCCCcccCCCCHHHHHH
Confidence            99998 88999999999999999999999989999999999999998653322111111123788899999999999999


Q NP_000282.1     324 YAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELL  403 (417)
Q Consensus       324 ~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L  403 (417)
                      |.++|++|||||||||||+||+++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||||
T Consensus       303 ~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~ai~~~~~~~a~sivGGGdT~~~~~~~g~~~~~s~vStgGGA~Le~L  382 (398)
T 1VPE_A          303 FKQKLSDAKTVVWNGPMGVFEIDDFAEGTKQVALAIAALTEKGAITVVGGGDSAAAVNKFGLEDKFSHVSTGGGASLEFL  382 (398)
T ss_dssp             HHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEEESHHHHHHHHHTTCGGGSSEEESCHHHHHHHH
T ss_pred             HHHHHhcCCEEEEeCCCCcccCcccchhHHHHHHHHHHhhhCCcEEEEcchHHHHHHHHcCCCCcceEEEcchHHHHHHH
Confidence            99999999999999999999887899999999999976322478999999999998888888788999999999999999


Q NP_000282.1     404 EGKVLPGVDALSN  416 (417)
Q Consensus       404 ~G~~LPgl~aL~~  416 (417)
                      +|++||||++|++
T Consensus       383 ~G~~LPgl~aL~~  395 (398)
T 1VPE_A          383 EGKELPGIASMRI  395 (398)
T ss_dssp             TSSCCHHHHTSCB
T ss_pred             cCCCCCcHHHhhh
Confidence            9999999999975


No 10
>4FEY_A Phosphoglycerate kinase (E.C.2.7.2.3); Structural Genomics, NIAID, National Institute; HET: ADP; 2.3A {Francisella tularensis subsp. tularensis}
Probab=100.00  E-value=5.5e-110  Score=841.97  Aligned_cols=388  Identities=44%  Similarity=0.740  Sum_probs=352.5  Template_Neff=6.400

Q NP_000282.1       2 SLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         2 ~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      .||++++++|.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||
T Consensus         2 ~~~~~~~l~~~~l~gK~vl~RvD~NVPl~~~~i~dd~RI~~~lpTI~~Ll~~ga-~vvl~sHlGrP~~~~~~~~~Sl~pv   80 (395)
T 4FEY_A            2 NAMSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGG-AVILMSHLGRPTEGEYDSQFSLEPV   80 (395)
T ss_dssp             --CCSCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHTHHHHHHHHHHTC-EEEEECCCSCCCTTSCCGGGCSHHH
T ss_pred             CcccccccccccCCCCEEEEEeeCCCcccCCccCCcHHHHHHHHHHHHHHHCCC-EEEEEeecCCCCCCCCCcccCHHHH
Confidence            478899999999999999999999999988899999999999999999999999 5999999999987522458999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|++.      .++++|+|+||||+|||++|+++               +.+|+++||+++|+|
T Consensus        81 a~~L~~~l~~~v~f~~d~~~~------~~~~~g~illLENlRf~~~E~~~---------------~~~fa~~La~l~Diy  139 (395)
T 4FEY_A           81 AKALSEIINKPVKFAKDWLDG------VDVKAGEIVMCENVRFNSGEKKS---------------TDDLSKKIASLGDVF  139 (395)
T ss_dssp             HHHHHHHHCSCEEEESSTTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEE
T ss_pred             HHHHHHHhCCceeecccccCC------CCCCCCeEEEEecccccCcccCC---------------chHHHHHHHhcchHh
Confidence            999999998779999999884      27889999999999999876421               367999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGG  239 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~  239 (417)
                      |||||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+
T Consensus       140 VnDAF~~~HR~~aS~vgi~~~lp~s~aG~l~~kEl~~L~~~~~~p~~P~v~IlGGaKv~dKi~~i~~Ll~~~d~iligG~  219 (395)
T 4FEY_A          140 VMDAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGG  219 (395)
T ss_dssp             EECCGGGTTSCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHTSCCSSEEEEEEESCHHHHHHHHHHHTTTCSEEEEEEH
T ss_pred             hhhcHhHcchhccccccccccCCcchHhHHHHHHHHHHHHHHhCCCCCeEEEECCCcHHHHHHHHHHHHHhCCEEEeccH
Confidence            9999999999999999998  66689999999999999999999999999999999999999999999999999999999


Q NP_000282.1     240 MAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPE  319 (417)
Q Consensus       240 ~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~  319 (417)
                      ||++||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++..+.... ......+|++|+++||||+
T Consensus       220 ~a~tfl~a~-g~~vg~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~~v~~~~~~~~~~~-~~~~~~ip~~~~~~DIGp~  297 (395)
T 4FEY_A          220 IANTFIKAE-GFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDVRVAKEFSENAQAI-IKKVSDVVADEMILDIGPE  297 (395)
T ss_dssp             HHHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHTTCBCCCCSEEEEESSSSTTCCCE-EEEGGGCCTTCEEEEECHH
T ss_pred             HHHHHHHHc-CCccCCcccchhHHHHHHHHHHHHHHhCCceeeeeeEEecccccccccce-EeeHHHCCCCcEeccCCHH
Confidence            999999998 88999999999889999999999999999999999999998754322211 1112478899999999999


Q NP_000282.1     320 SSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGAS  399 (417)
Q Consensus       320 Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~  399 (417)
                      |++.|.+.|++|||||||||||+||.++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+
T Consensus       298 Ti~~~~~~i~~aktI~wnGP~G~~E~~~f~~GT~~i~~aia~~---~a~~ivGGGdT~~~~~~~g~~~~~s~vStgGGA~  374 (395)
T 4FEY_A          298 SQKIIAELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQS---HAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAF  374 (395)
T ss_dssp             HHHHHHHHHHHCSEEEEECCSSCTTSGGGCHHHHHHHHHHHHH---CSEEEEESHHHHHHHHHTTCSTTSSEEECCSHHH
T ss_pred             HHHHHHHHHHhCCEEEEcCCCCcccccccChHHHHHHHHHHhC---CCcEEEechHHHHHHHHcCCCcCcEEEEcchHHH
Confidence            9999999999999999999999998888999999999999762   6899999999998888889888999999999999


Q NP_000282.1     400 LELLEGKVLPGVDALSN  416 (417)
Q Consensus       400 Le~L~G~~LPgl~aL~~  416 (417)
                      ||||+|+.||||++|++
T Consensus       375 Le~L~G~~LPgleaL~~  391 (395)
T 4FEY_A          375 LEFLEGKKLPAIEILKE  391 (395)
T ss_dssp             HHHHTTCCCHHHHHHHH
T ss_pred             HHHHcCCCCchHHHHHH
Confidence            99999999999999975


No 11
>1V6S_B Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, Thermus thermophilus, RIKEN; HET: GOL; 1.5A {Thermus thermophilus} SCOP: c.86.1.1
Probab=100.00  E-value=1.2e-109  Score=838.81  Aligned_cols=386  Identities=44%  Similarity=0.774  Sum_probs=350.7  Template_Neff=6.500

Q NP_000282.1       7 LTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELK   86 (417)
Q Consensus         7 ~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L~   86 (417)
                      ++++|.|++|||||||+|+|||+++++|.|++||++++|||+||++ ++++|||+||+|||+++  ++.+||+||+++|+
T Consensus         2 ~~l~d~~l~gK~vl~R~D~NVPi~~~~i~d~~RI~~~lpTI~~Ll~-~~~~vvl~sHlGrP~~~--~~~~Sl~pva~~L~   78 (390)
T 1V6S_B            2 RTLLDLDPKGKRVLVRVDYNVPVQDGKVQDETRILESLPTLRHLLA-GGASLVLLSHLGRPKGP--DPKYSLAPVGEALR   78 (390)
T ss_dssp             CBGGGCCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHH-TTCEEEEECCCSCCSSC--CGGGCSHHHHHHHH
T ss_pred             CCccccCCCCCEEEEEeeccccccCCccCCcHHHHhHHHHHHHHHh-CCCeEEEEeccCCCCCC--CcccchHHHHHHHH
Confidence            5677788999999999999999998899999999999999999999 54359999999999865  35799999999999


Q NP_000282.1      87 SLLGKDVLFLKDCVG-PEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDA  165 (417)
Q Consensus        87 ~~l~~~v~f~~~~~~-~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDA  165 (417)
                      ++|+. |.|++++++ +++.+.++.+++|+|+||||+|||++|+++               +.+|+++||+++|+|||||
T Consensus        79 ~~l~~-v~f~~~~~~~~~~~~~i~~~~~g~i~lLENlRf~~~E~~n---------------~~~fa~~La~l~DiyVNDA  142 (390)
T 1V6S_B           79 AHLPE-ARFAPFPPGSEEARREAEALRPGEVLLLENVRFEPGEEKN---------------DPELSARYARLGEAFVLDA  142 (390)
T ss_dssp             TTCTT-EEECCSCTTSHHHHHHHHTCCTTCEEECCCGGGSTTTTTT---------------CHHHHHHHGGGCSEEEECC
T ss_pred             HHCCC-cEeCCCCCCcHHHHHHHHHcCCCCEEEEeccCCCCCcccC---------------CHHHHHHHHhhcceEeeec
Confidence            99986 899998888 677778889999999999999999866422               3679999999999999999


Q NP_000282.1     166 FGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAFT  243 (417)
Q Consensus       166 Fg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~t  243 (417)
                      ||++||.|||+++++  +| ++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+|||+
T Consensus       143 F~~~HR~hAS~vgi~~~lp-s~aG~ll~kEl~~L~~~l~~p~~P~v~IlGGaKv~dKi~~i~~Ll~~~D~IligG~~a~t  221 (390)
T 1V6S_B          143 FGSAHRAHASVVGVARLLP-AYAGFLMEKEVRALSRLLKDPERPYAVVLGGAKVSDKIGVIESLLPRIDRLLIGGAMAFT  221 (390)
T ss_dssp             GGGTTSCCCCCCCGGGTSC-EEECHHHHHHHHHHHHTTSCCCSSEEEEECCSCGGGTHHHHHHHGGGCSEEEECSTHHHH
T ss_pred             hhhcCcccchhhHHHhhHH-hhccHHHHHHHHHHHHHHcCCCCCEEEEEcCCCHHHHHHHHHHHHHHCCEEEEcchHHHH
Confidence            999999999999999  67 899999999999999999999999999999999999999999999988999999999999


Q NP_000282.1     244 FLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSKK  323 (417)
Q Consensus       244 fl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~~  323 (417)
                      ||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+.+...... ...+...+|++|+++||||+|++.
T Consensus       222 fL~a~-g~~ig~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~ip~~~~~~DIGp~Ti~~  299 (390)
T 1V6S_B          222 FLKAL-GGEVGRSLVEEDRLDLAKDLLGRAEALGVRVYLPEDVVAAERIEAGVET-RVFPARAIPVPYMGLDIGPKTREA  299 (390)
T ss_dssp             HHHHT-TCBCTTCCCCGGGHHHHHHHHHHHHHTTCEEECCSEEEEESSCCTTCCC-EEEETTBCCTTCEEEEECHHHHHH
T ss_pred             HHHHc-CCCccccccchhHHHHHHHHHHHHHHhCCeEEceeceeeccccccCCce-EEecCccCCCCcccccCCHHHHHH
Confidence            99998 8899999999999999999999888899999999999998865322111 112224788899999999999999


Q NP_000282.1     324 YAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLELL  403 (417)
Q Consensus       324 ~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~L  403 (417)
                      |+++|++|||||||||||+||+++|++||+++++++++++  ++++|+|||||+++++++|+.++++||||||||+||||
T Consensus       300 ~~~~i~~aktI~wnGp~G~~E~~~f~~GT~~i~~~i~~~~--~a~~iiGGGdT~~~~~~~g~~~~~~~vStgGGA~L~~L  377 (390)
T 1V6S_B          300 FARALEGARTVFWNGPMGVFEVPPFDEGTLAVGQAIAALE--GAFTVVGGGDSVAAVNRLGLKERFGHVSTGGGASLEFL  377 (390)
T ss_dssp             HHHHHTTCSEEEEESCSSCTTSTTTTHHHHHHHHHHHHCS--SCEEEEESHHHHHHHHHTTCGGGSSEECCSSSCHHHHH
T ss_pred             HHHHHhcCCEEEEeCCCcccCCCCcchHHHHHHHHHHHcc--CCEEEEeCHHHHHHHHHcCCCCcceEEecchHHHHHHH
Confidence            9999999999999999999988889999999999997632  78999999999999999898889999999999999999


Q NP_000282.1     404 EGKVLPGVDALSN  416 (417)
Q Consensus       404 ~G~~LPgl~aL~~  416 (417)
                      +|+.||||++|++
T Consensus       378 ~g~~LPgl~aL~~  390 (390)
T 1V6S_B          378 EKGTLPGLEVLEG  390 (390)
T ss_dssp             HHSCCHHHHTTCC
T ss_pred             hcCCCCcchhccC
Confidence            9999999999974


No 12
>3ZLB_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); TRANSFERASE; HET: ANP, GOL; 1.78A {STREPTOCOCCUS PNEUMONIAE}
Probab=100.00  E-value=1.6e-109  Score=839.96  Aligned_cols=394  Identities=46%  Similarity=0.789  Sum_probs=353.2  Template_Neff=6.500

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |++++++|.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vlvR~D~NVPi~~~~i~dd~RI~~~lpTI~~Ll~~ga-kvil~sHlGRP~g~~~~~~~Sl~pva~   79 (398)
T 3ZLB_A            1 MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTIKYIIEQGG-RAILFSHLGRVKEESDKAGKSLAPVAA   79 (398)
T ss_dssp             CCBCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSGGGSTTCCSHHHHH
T ss_pred             CCccccccccCCCCEEEEEeeCCCccCCCCcCCChHHHHHHHHHHHHHHCCC-eEEEEeecCccCCcccccCcchHHHHH
Confidence            4677888888999999999999999998899999999999999999999999 599999999998753134799999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGD-VYV  162 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~D-iyV  162 (417)
                      +|+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|... +.          .++.+|+++||+++| +||
T Consensus        80 ~L~~~l~~~v~f~~~~~g~~~~~~i~~~~~g~i~lLENlRf~~~E~~~-e~----------~n~~~fa~~La~l~d~iyV  148 (398)
T 3ZLB_A           80 DLAAKLGQDVVFPGVTRGAELEAAINALEDGQVLLVENTRYEDVDGKK-ES----------KNDPELGKYWASLGDGIFV  148 (398)
T ss_dssp             HHHHHHTSCEECCSCSSSHHHHHHHHTCCTTCEEECCCGGGGGTTTCT-TT----------TTCHHHHHHHHHTSSSEEE
T ss_pred             HHHHHhCCceeCCCCCCCHHHHHHHHhccCCCEEEEecccccCCCCCc-cc----------cccHHHHHHHHhcCCcEEE
Confidence            999999877999999999888888899999999999999999865211 10          114789999999988 999


Q NP_000282.1     163 NDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGM  240 (417)
Q Consensus       163 NDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~  240 (417)
                      ||||+++||.|||+++++  +|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+|
T Consensus       149 NDAF~~~HR~hAS~vgi~~~lp~s~aG~ll~kEl~~L~~~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~  228 (398)
T 3ZLB_A          149 NDAFGTAHRAHASNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEKADKVLIGGGM  228 (398)
T ss_dssp             ECCGGGTTSCCCCCCCHHTTSSEEEECHHHHHHHCCCCCHHHSCCSSEEEEECSSCSTTTHHHHHHHHHHCSEEEECTTH
T ss_pred             ecchhhcccccchhhhhhHhhchHhHHHHHHHHHHHHHHHHHCCCCCEEEEEcCCCHHHHHHHHHHHHHHhCceEeCchH
Confidence            999999999999999999  666899999999999999999999999999999999999999999999988999999999


Q NP_000282.1     241 AFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPES  320 (417)
Q Consensus       241 a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~T  320 (417)
                      ||+||+|+ |+++|+|++|++..+.|++++++   ++++|++|+|++|.+.+...... ...+...+|++|+++||||+|
T Consensus       229 a~tfL~a~-g~~ig~S~~e~~~~~~a~~ll~~---~~~ki~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~~DIGp~T  303 (398)
T 3ZLB_A          229 TYTFYKAQ-GIEIGNSLVEEDKLDVAKALLEK---ANGKLILPVDSKEANAFAGYTEV-RDTEGEAVSEGFLGLDIGPKS  303 (398)
T ss_dssp             HHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHH---STTCEECCSCEEEESSSSSCSCE-EECSSSCCCTTCEEEEECHHH
T ss_pred             HHHHHHHc-CCcccCcccccchHHHHHHHHHH---cCCceEeeccchhhhcccCCCce-eeeccccccCCCeeecCCHHH
Confidence            99999998 88999999999888999999875   47899999999998864332111 111124788899999999999


Q NP_000282.1     321 SKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASL  400 (417)
Q Consensus       321 i~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~L  400 (417)
                      ++.|.+.|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++|+.++|+||||||||+|
T Consensus       304 i~~~~~~I~~aktI~wnGP~G~~E~~~f~~GT~~i~~~i~~~~--~a~~iiGGGdT~~~~~~~g~~~~~s~vStgGGA~L  381 (398)
T 3ZLB_A          304 IAKFDEALTGAKTVVWNGPMGVFENPDFQAGTIGVMDAIVKQP--GVKSIIGGGDSAAAAINLGRADKFSWISTGGGASM  381 (398)
T ss_dssp             HHHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHTST--TCEEEECCHHHHHHHHHTTCGGGSSEECCCTHHHH
T ss_pred             HHHHHHHHhcCCEEEEeCCCCccCCccccchHHHHHHHHHcCC--CCcEEEecccHHHHHHHcCCCCCCeEEEcchHHHH
Confidence            9999999999999999999999998889999999999997632  78999999999988888888778999999999999


Q NP_000282.1     401 ELLEGKVLPGVDALSN  416 (417)
Q Consensus       401 e~L~G~~LPgl~aL~~  416 (417)
                      |||+|+.||||++|++
T Consensus       382 e~L~G~~LPgl~aL~~  397 (398)
T 3ZLB_A          382 ELLEGKVLPGLAALTE  397 (398)
T ss_dssp             HHHTTCCCHHHHTSCB
T ss_pred             HHHcCCCCchHHHhhc
Confidence            9999999999999975


No 13
>4EHJ_A Phosphoglycerate kinase (E.C.2.7.2.3); Structural Genomics, Center for Structural; HET: MSE; 2.71A {Francisella tularensis subsp. tularensis}
Probab=100.00  E-value=2e-109  Score=837.07  Aligned_cols=386  Identities=44%  Similarity=0.744  Sum_probs=350.7  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |++++++|.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vl~R~D~NVpl~~~~i~dd~RI~~~lpTI~~Ll~~ga-~vvl~sHlGrP~~~~~~~~~Sl~pva~   79 (392)
T 4EHJ_A            1 MSFLTLKDVDLKDKKVLVRVDFNVPVKDGKVTSKVRIEAAIPTIQYILDQGG-AVILMSHLGRPTEGEYDSQFSLEPVAK   79 (392)
T ss_dssp             -CCCBGGGSCCTTCEEEEECCCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCTTCCCGGGCSHHHHH
T ss_pred             CCccccccccCCCCEEEEEeeCCCcccCCccCCcHHHHHHHHHHHHHHHCCC-eEEEEeecCCCCCCCCCcccCHHHHHH
Confidence            4578888888999999999999999988899999999999999999999999 699999999998752245899999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|+++|++.      .++++|+|+||||+|||++|+++               +.+|+++||+++|+|||
T Consensus        80 ~L~~~l~~~v~f~~d~~~~------~~~~~g~illLENlRf~~~E~~~---------------~~~fa~~La~~~DiyVn  138 (392)
T 4EHJ_A           80 ALSEIINKPVKFAKDWLDG------VDVKAGEIVMCENVRFNSGEKKS---------------TDDLSKKIASLGDVFVM  138 (392)
T ss_dssp             HHHHHHTSCEEEETTCTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEEEE
T ss_pred             HHHHHhCCceeecccccCC------CCCCCCeEEEEecccccCcccCC---------------chHHHHHHHhcchHhhh
Confidence            9999998779999999885      27889999999999999876421               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|+++||.|++||+||
T Consensus       139 DAF~~~HR~~aS~vgi~~~lp~s~aG~l~~kEl~~L~~~~~~p~~P~v~IiGGaKv~dKi~~i~~Ll~~~D~IligG~~a  218 (392)
T 4EHJ_A          139 DAFATAHRAQASTYGVAKYIPVACAGILLTNEIQALEKALKSPKKPMAAIVGGSKVSTKLSVLNNLLDKVEILIVGGGIA  218 (392)
T ss_dssp             CCGGGTTSCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHTSCCSSEEEEEECSCHHHHHHHHHHHTTTCSEEEEETHHH
T ss_pred             hcHhHccccccccccccccCCcchHhHHHHHHHHHHHHHHhCCCCCEEEEECCCcHHHHHHHHHHHHHhCCEEEeccHHH
Confidence            99999999999999999  6668999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      ++||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++..+.... ......+|++|+++||||+|+
T Consensus       219 ~tfl~a~-g~~vg~s~~e~~~~~~a~~il~~a~~~~~kI~lP~D~~v~~~~~~~~~~~-~~~~~~i~~~~~~~DIGp~T~  296 (392)
T 4EHJ_A          219 NTFIKAE-GFDVGNSLYEQDLVAEATEILAKAKALGVNIPVPVDVRVAKEFSENAQAI-IKKVSDVVADEMILDIGPESQ  296 (392)
T ss_dssp             HHHHHHT-TCCCTTCSCCGGGHHHHHHHHHHHHHHTCBCCCCSEEEEESSCSTTCCCE-EEEGGGCCTTCEEEEECHHHH
T ss_pred             HHHHHHc-CCccCCcccchhHHHHHHHHHHHHHHhCCceeeeeeEEecccccccccce-EeeHHHCCCCcEeccCCHHHH
Confidence            9999998 88999999999888999999999988999999999999998754322211 111247888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|++.|++|||||||||||+||.++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       297 ~~~~~~i~~aktI~wnGp~G~~E~~~f~~GT~~i~~ai~~~---~a~~vvGGGdT~~~~~~~g~~~~~~~vStgGGA~Le  373 (392)
T 4EHJ_A          297 KIIAELLKSANTILWNGPVGVFEFDNFAEGTKALSLAIAQS---HAFSVAGGGDTIAAIEKFGIKDQVSYISTAGGAFLE  373 (392)
T ss_dssp             HHHHHHHHHCSEEEEECCSSCTTSGGGCHHHHHHHHHHHHC---CSEEEECSHHHHHHHHHHTCGGGSSEECCCSHHHHH
T ss_pred             HHHHHHHHhCCEEEEcCCCCcccccccChHHHHHHHHHHhC---CCcEEEechHHHHHHHHcCCCcCcEEEEcchHHHHH
Confidence            99999999999999999999998888999999999999762   689999999999888888988899999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       374 ~L~G~~LPgl~aL~~  388 (392)
T 4EHJ_A          374 FLEGKKLPAIEILKE  388 (392)
T ss_dssp             HHTTCCCHHHHHHHH
T ss_pred             HHcCCCCchHHHHHH
Confidence            999999999999975


No 14
>16PK_A 3-PHOSPHOGLYCERATE KINASE, 1,1,5,5-TETRAFLUOROPHOSPHOPENTYLPHOSPHONIC ACID ADENYLATE; KINASE, PHOSPHOGLYCERATE, TERNARY COMPLEX, GLYCOLYSIS; HET: EPE, BIS; 1.6A {Trypanosoma brucei} SCOP: c.86.1.1
Probab=100.00  E-value=4.2e-109  Score=840.30  Aligned_cols=395  Identities=47%  Similarity=0.803  Sum_probs=351.6  Template_Neff=6.400

Q NP_000282.1       6 KLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPM-------------   72 (417)
Q Consensus         6 ~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~-------------   72 (417)
                      ++++++.|++|||||||+|+|||+++++|.|++||++++|||+||++ +|++|||+||+|||+++..             
T Consensus         2 ~~~l~~~~l~gK~vlvR~D~NVPl~~~~i~dd~RI~~~lpTI~~Ll~-~~~kvil~sHlGRP~g~~~~~~~~~~~~~~~~   80 (415)
T 16PK_A            2 KKSINECDLKGKKVLIRVDFNVPVKNGKITNDYRIRSALPTLKKVLT-EGGSCVLMSHLGRPKGIPMAQAGKIRSTGGVP   80 (415)
T ss_dssp             BCBGGGSCCTTCEEEEEECCCCCEETTEESCCHHHHHHHHHHHHHHH-TTCEEEEECCCSCCCCBCGGGHHHHHHTTCCT
T ss_pred             CCccchhhcCCCEEEEEeeCCCcccCCccCCcHHHHHHHHHHHHHHH-cCCeEEEEeecCCCCCCChhhccccccCCCCC
Confidence            56777788999999999999999987899999999999999999999 5545999999999986320             


Q NP_000282.1      73 --PDKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAF  150 (417)
Q Consensus        73 --~~~~Sl~~va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~f  150 (417)
                        .+.+||+||+++|+++|+.+|.|+++|+|  +.+.++.+++|+|+||||+|||++|++++ +          +++.+|
T Consensus        81 ~~~~~~Sl~pva~~L~~~l~~~V~f~~~~~~--~~~~i~~~~~g~i~lLENlRF~~~E~~~~-~----------~~~~~f  147 (415)
T 16PK_A           81 GFQQKATLKPVAKRLSELLLRPVTFAPDCLN--AADVVSKMSPGDVVLLENVRFYKEEGSKK-A----------KDREAM  147 (415)
T ss_dssp             TCCGGGCSHHHHHHHHHHHTSCCEEESCTTS--CHHHHHTCCTTCEEEECCGGGBGGGGCSS-H----------HHHHHH
T ss_pred             CcchhccHHHHHHHHHHHhCCcceeCCCcCC--HHHHHHhCCCCCEEEEecccccccccccc-c----------ccHHHH
Confidence              12689999999999999867999999998  45567799999999999999998765221 0          113789


Q NP_000282.1     151 RASLSKLGDVYVNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNML  228 (417)
Q Consensus       151 a~~LA~l~DiyVNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll  228 (417)
                      +++||+++|+|||||||++||.|||+++++  +|+++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+
T Consensus       148 a~~La~l~DiyVNDAF~~~HR~hAS~vgi~~~lp~s~aG~ll~kEl~~L~~~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll  227 (415)
T 16PK_A          148 AKILASYGDVYISDAFGTAHRDSATMTGIPKILGNGAAGYLMEKEISYFAKVLGNPPRPLVAIVGGAKVSDKIQLLDNML  227 (415)
T ss_dssp             HHHHHTTCSEEEEECGGGTTSCCCCCCCHHHHHTCCEECHHHHHHHHHHHHHHSCCCSSEEEEECSSCSGGGHHHHHHHG
T ss_pred             HHHHHhccCeEEeechhhcccCcchhccHhHhhcccchHHHHHHHHHHHHHHHcCCCCCeEEEEcCCCHHHHHHHHHHHH
Confidence            999999999999999999999999999999  665899999999999999999999999999999999999999999999


Q NP_000282.1     229 DKVNEMIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIP  308 (417)
Q Consensus       229 ~~~D~iligG~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~  308 (417)
                      +++|.|+|||+|||+||+|+ |+++|+|++|++..+.|++++++|+.++++|++|+|++|.+++...... ...+.+.+|
T Consensus       228 ~~~D~IligG~~a~tfl~a~-g~~vG~s~~e~~~~~~a~~ll~~a~~~~~kI~lP~D~~v~~~~~~~~~~-~~~~~~~i~  305 (415)
T 16PK_A          228 QRIDYLLIGGAMAYTFLKAQ-GYSIGKSKCEESKLEFARSLLKKAEDRKVQVILPIDHVCHTEFKAVDSP-LITEDQNIP  305 (415)
T ss_dssp             GGCSEEEECTTHHHHHHHHH-TCCCTTCCCCGGGHHHHHHHHHHHHHTTCEEECCSSEEEESSSSCCSSC-EECSSSCCC
T ss_pred             HHcCEEEeCchHHHHHHHHc-CCcccccccchhHHHHHHHHHHHHHhcCCEEEceeceeeccccCCCCCC-ceeccccCC
Confidence            98899999999999999998 8999999999999999999999888899999999999999875321111 111224788


Q NP_000282.1     309 AGWMGLDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKAT-SRGCITIIGGGDTATCCAKWNTED  387 (417)
Q Consensus       309 ~~~~~~DIGp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~-~~~~~~ivGGGdT~~~~~~~g~~~  387 (417)
                      ++|+++||||+|++.|++.|++|||||||||||+||+++|++||+++++++++++ .+++++|+|||||+++++++|+.+
T Consensus       306 ~~~~~~DIGp~Ti~~~~~~i~~aktI~wnGp~G~~E~~~f~~GT~~i~~~l~~~~~~~~a~~vvGGGdT~~~~~~~~~~~  385 (415)
T 16PK_A          306 EGHMALDIGPKTIEKYVQTIGKCKSAIWNGPMGVFEMVPYSKGTFAIAKAMGRGTHEHGLMSIIGGGDSASAAELSGEAK  385 (415)
T ss_dssp             TTCEEEEECHHHHHHHHHHHTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHHHCCEEEECSHHHHHHHHHTTCTT
T ss_pred             CCCcccccCHHHHHHHHHHHHcCCEEEEeCCCccccCCccccchHHHHHHHHhhcccCCceEEEcchhHHHHHHHhCCcc
Confidence            8999999999999999999999999999999999998889999999999997632 247899999999998888888888


Q NP_000282.1     388 KVSHVSTGGGASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       388 ~~~~vStgGgA~Le~L~G~~LPgl~aL~~  416 (417)
                      +++||||||||+||||+|++||||++|++
T Consensus       386 ~~s~vStgGGA~Le~L~Gk~LPgl~aL~~  414 (415)
T 16PK_A          386 RMSHVSTGGGASLELLEGKTLPGVTVLDD  414 (415)
T ss_dssp             TSSEECSCHHHHHHHHTTCCCHHHHTSCB
T ss_pred             cCeEEEcchHHHHHHHcCCCCCchHhccc
Confidence            89999999999999999999999999975


No 15
>3OZ7_B Phosphoglycerate kinase (E.C.2.7.2.3); Phosphoglycerate kinase, Transferase, ATP Binding; HET: SO4; 2.7A {Plasmodium falciparum}
Probab=100.00  E-value=4.5e-109  Score=840.55  Aligned_cols=413  Identities=61%  Similarity=0.995  Sum_probs=361.2  Template_Neff=6.400

Q NP_000282.1       3 LSNKLTLDKL-DVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPV   81 (417)
Q Consensus         3 ~~~~~~i~~~-~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~v   81 (417)
                      ...++++.+. |++||+||||+|+|||+++++|.|++||++++|||+||+++||++|||+||+|||+++. ++.+||+||
T Consensus         4 ~~~~~~~~~~~~l~gk~vlvR~D~NVPi~~~~i~d~~Ri~~~lpTI~~Ll~~gak~vvl~sHlGRP~g~~-~~~~Sl~~v   82 (417)
T 3OZ7_B            4 LGNKLSISDLKDIKNKKVLVRVDFNVPIENGIIKDTNRITATLPTINHLKKEGASKIILISHCGRPDGLR-NEKYTLKPV   82 (417)
T ss_dssp             TTSCCBGGGCCCCTTCEEEEEECCCCCEETTEESCCHHHHTTHHHHHHHHHTTCSEEEEECCCSCCTTSC-CGGGCCSHH
T ss_pred             CCCCCChhhhhhcCCCEEEEEEeCCCcccCCccCCChhHHhHHHHHHHHHHcCCCEEEEEeeCCCCCCCC-CcccchHHH
Confidence            3567888876 89999999999999999888999999999999999999999994499999999998764 568999999


Q NP_000282.1      82 AVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVY  161 (417)
Q Consensus        82 a~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Diy  161 (417)
                      +++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|++++++++.+..+.+.+++.+|++.||+++|+|
T Consensus        83 a~~L~~~l~~~v~f~~~~~g~~~~~~i~~~~~g~illLENlRf~~~E~~~~~~a~~~~~~~~~~~~~~fa~~La~~~diy  162 (417)
T 3OZ7_B           83 AETLKGLLGEEVLFLNDCVGKEVEDKINAAKENSVILLENLRFHIEEEGKGVDANGNKVKANKEDVEKFQNDLTKLADVF  162 (417)
T ss_dssp             HHHHHHHHTSCCEEESCSSSHHHHHHHHHSCTTEEEEECCGGGSHHHHSEEECTTSCEEECCHHHHHHHHHHHHTTCSEE
T ss_pred             HHHHHHHhCCEEEEecccCCHHHHHHHHHccCCCEEEEecccccchhccCCCCCCCCccccCHHhHHHHHHHHhhcCCEE
Confidence            99999999877999999999888888899999999999999999977632111000000111112467999999999999


Q NP_000282.1     162 VNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       162 VNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||||+++||.|||+++++...++||++|++||++|.+++++|+||+++|+||+|++||+++|++|+++||.|+|||+||
T Consensus       163 VnDAF~~~HR~~ASv~gi~~~~~~aG~l~~kEi~~L~~~~~~p~rP~v~IlGG~Kv~dKi~~i~~Ll~~~D~IligG~~a  242 (417)
T 3OZ7_B          163 INDAFGTAHRAHSSMVGVKLNVKASGFLMKKELEYFSKALENPQRPLLAILGGAKVSDKIQLIKNLLDKVDRMIIGGGMA  242 (417)
T ss_dssp             EEECGGGTTSCCHHHHCCCCSEEEECHHHHHHHHHHHHHHSSCCSSEEEEECSSCSGGGHHHHHHHHHHCSEEEECTTHH
T ss_pred             EecccccCCCCCCchHHHHhcHHhhCHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHhCCEEEECcHHH
Confidence            99999999999999999993228999999999999999999999999999999999999999999999999999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|++++++|+|++|++..+.|++++++|+.++++|++|+|++|.+....++....+...+.+|++|+++||||+|+
T Consensus       243 ~~fl~a~~~~~vg~s~~e~~~~~~a~~il~~a~~~~~ki~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  322 (417)
T 3OZ7_B          243 YTFKKVLNNMKIGTSLFDEAGSKIVGEIMEKAKAKNVQIFLPVDFKIADNFDNNANTKFVTDEEGIPDNWMGLDAGPKSI  322 (417)
T ss_dssp             HHHHHHHHCCCBTTCCCCTTTHHHHHHHHHHHHHTTCEEECCSEEEEESSSSTTSCEEEEETTTCBCTTCEEEEECHHHH
T ss_pred             HHHHHHHCCCcCCccccchhhHHHHHHHHHHHHHcCCEEEEeeeeeecccCCCCCcCceecCcCCCCCCcccccCCHHHH
Confidence            99999984558999999998999999999998889999999999999987533221111222237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|+++|++|||||||||||+||.++|++||+++++++++++++++++|+|||||+++++++|+.++++||||||||+||
T Consensus       323 ~~~~~~I~~aktI~wnGplG~~E~~~f~~GT~~i~~~l~~~~~~~a~~vvGGGdT~~~~~~~g~~~~~~~vSTgGGA~Le  402 (417)
T 3OZ7_B          323 ENYKDVILTSKTVIWNGPQGVFEMPNFAKGSIECLNLVVEVTKKGAITIVGGGDTASLVEQQNKKNEISHVSTGGGASLE  402 (417)
T ss_dssp             HHHHHHHHTCSEEEEESCSBCTTSGGGCHHHHHHHHHHHHHHHHTCEEEECSHHHHHHHHHHTCGGGSSEECCCSHHHHH
T ss_pred             HHHHHHHHhCCEEEEeCCCccccCCCcChhHHHHHHHHHHHhcCCCEEEEeChHHHHHHHHcCCCCCcEEEEechHHHHH
Confidence            99999999999999999999999888999999999999763224789999999999988888887789999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|++||||++|++
T Consensus       403 ~L~G~~LPgi~aL~~  417 (417)
T 3OZ7_B          403 LLEGKELPGVLALSN  417 (417)
T ss_dssp             HHTTCCCHHHHTSCC
T ss_pred             HHcCCCCChhHhhcC
Confidence            999999999999974


No 16
>4DG5_A Phosphoglycerate kinase (E.C.2.7.2.3); Bi-lobal protein, Transferase, ATP Synthesis; 2.3A {Staphylococcus aureus}
Probab=100.00  E-value=5.2e-109  Score=836.15  Aligned_cols=392  Identities=44%  Similarity=0.770  Sum_probs=353.4  Template_Neff=6.300

Q NP_000282.1       5 NKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVE   84 (417)
Q Consensus         5 ~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~   84 (417)
                      .++++.+.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||+++
T Consensus         9 ~~~~~~~~dl~gK~vlvR~D~NVP~~~~~i~dd~RI~~~lpTI~~L~~~ga-kvvl~sHlGrP~g~~~~~~~Sl~pva~~   87 (403)
T 4DG5_A            9 AKKIVSDLDLKGKTVLVRADFNVPLKDGEITNDNRIVQALPTIQYIIEQGG-KIVLFSHLGKVKEESDKAKLTLRPVAED   87 (403)
T ss_dssp             CBCBGGGSCCTTCEEEEECCCCCCCSSSCCSCTHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCSGGGSGGGCSHHHHHH
T ss_pred             ccccCCchhcCCCEEEEEeecccccCCCCcCCchHHHHHHHHHHHHHHCCC-EEEEEeccCccCCccchhhcchHHHHHH
Confidence            467788889999999999999999998899999999999999999999999 5999999999987522457999999999


Q NP_000282.1      85 LKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVND  164 (417)
Q Consensus        85 L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVND  164 (417)
                      |+++|+.+|.|+++|+|+++++.++.+++|+|+||||+|||++|.+. +.          +++.+|++.||+++|+||||
T Consensus        88 L~~~l~~~V~f~~d~~g~~~~~~i~~~~~g~illLENlRf~~~E~~~-e~----------~n~~~fa~~LA~l~DiyVND  156 (403)
T 4DG5_A           88 LSKKLDKEVVFVPETRGEKLEAAIKDLKEGDVLLVENTRYEDLDGKK-ES----------KNDPELGKYWASLGDVFVND  156 (403)
T ss_dssp             HHHHHTSCCEEESCSSSHHHHHHHHTCCTTCEEEECCGGGGGTTTTT-TT----------TTCHHHHHHHHTTCSEEEEC
T ss_pred             HHHHcCCeEEecCCcCCHHHHHHHHhccCCCEEEEccccccCCCCCc-cc----------ccCHHHHHHHHhcchHhhhc
Confidence            99999877999999999888888899999999999999999865211 10          11478999999999999999


Q NP_000282.1     165 AFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMAF  242 (417)
Q Consensus       165 AFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a~  242 (417)
                      |||++||.|||+++++  +| ++||++|++|+++|.+++++|+||+++|+||+|++||+++|++|++++|.|++||+|||
T Consensus       157 AF~~~HR~hAS~vgi~~~lp-s~aG~ll~kEl~~L~k~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~IligG~lA~  235 (403)
T 4DG5_A          157 AFGTAHREHASNVGISTHLE-TAAGFLMDKEIKFIGGVVNDPHKPVVAILGGAKVSDKINVIKNLVNIADKIIIGGGMAY  235 (403)
T ss_dssp             CGGGTTSCCCCCCCHHTSSC-EEECHHHHHHCCCCCHHHHSCCSSEEEEECSSCHHHHHHHHHHHTTTCSEEEECSTTHH
T ss_pred             CHhHccCcCcchHHHHHHHH-HHhhHHHHHHHHHHHHHHhCCCCCEEEEEcCCcHHHHHHHHHHHHHHcCEEEEcchHHH
Confidence            9999999999999999  67 89999999999999999999999999999999999999999999998899999999999


Q NP_000282.1     243 TFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESSK  322 (417)
Q Consensus       243 tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti~  322 (417)
                      +||+|+ |+++|+|++|++..+.|++++++   ++++|++|+|++|.+.+..++... ..+.+.+|++|+++||||+|++
T Consensus       236 tfL~a~-g~~vg~s~~e~~~~~~a~~ll~~---~~~ki~lP~D~~v~~~~~~~~~~~-~~~~~~i~~~~~~~DIGp~Ti~  310 (403)
T 4DG5_A          236 TFLKAQ-GKEIGISLLEEDKIDFAKDLLEK---HGDKIVLPVDTKVAKEFSNDAKIT-VVPSDSIPADQEGMDIGPNTVK  310 (403)
T ss_dssp             HHHHHT-TCCCTTSCCCGGGHHHHHHHHHH---STTTEECCSEEEEESSSSTTSCCE-EEEGGGCCTTCEEEEECHHHHH
T ss_pred             HHHHHc-CCeeeeeecchhhHHHHHHHHHH---ccCceEeeceeeeecccCCCCceE-EecCCCCCCCcccccCCHHHHH
Confidence            999998 88999999999888999998873   588999999999998754322211 1122578889999999999999


Q NP_000282.1     323 KYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLEL  402 (417)
Q Consensus       323 ~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le~  402 (417)
                      .|.+.|++|||||||||||+||.++|++||+++++++++++  ++++|+|||||+++++++|+.++++||||||||+|||
T Consensus       311 ~~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~aia~~~--~a~~ivGGGdT~~~~~~~g~~~~~~~vStGGGA~Le~  388 (403)
T 4DG5_A          311 LFADELEGAHTVVWNGPMGVFEFSNFAQGTIGVCKAIANLK--DAITIIGGGDSAAAAISLGFENDFTHISTGGGASLEY  388 (403)
T ss_dssp             HHHHTTTTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHCS--SSEEEECSHHHHHHHHHTTCGGGSSEECSCHHHHHHH
T ss_pred             HHHHHHhcCCEEEEeCCCccccCccccchHHHHHHHHHhcC--CCEEEEeCchHHHHHHHcCCCCCceEEEechHHHHHH
Confidence            99999999999999999999988889999999999997632  7899999999999998889888899999999999999


Q NP_000282.1     403 LEGKVLPGVDALSN  416 (417)
Q Consensus       403 L~G~~LPgl~aL~~  416 (417)
                      |+|+.||||++|++
T Consensus       389 L~Gk~LPgl~aL~~  402 (403)
T 4DG5_A          389 LEGKELPGIKAINN  402 (403)
T ss_dssp             HTTCCCHHHHTSCB
T ss_pred             HcCCCCCchHHhhc
Confidence            99999999999975


No 17
>6HXE_A Phosphoglycerate kinase (E.C.2.7.2.3); Complex, 3-phosphoglycerate, hinge binding, TRANSFERASE; HET: 3PG; 2.1A {Pseudomonas sp. 'TAC II 18'}
Probab=100.00  E-value=4.3e-108  Score=826.14  Aligned_cols=381  Identities=39%  Similarity=0.690  Sum_probs=341.5  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |.++++++.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++++||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vl~R~D~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~ga-~vil~sHlGrP~g~~~~~~~Sl~~va~   79 (387)
T 6HXE_A            1 MTVLKMTDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGA-AVMVCSHLGRPTEGEFSAENSLKPVAD   79 (387)
T ss_dssp             -CCCBGGGSCCTTCEEEEECCCCCCEETTEECCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCTTSCCGGGCSHHHHH
T ss_pred             CCccccchhhcCCCEEEEEeecCccccCCccCCcHHHHhHHHHHHHHHHcCC-cEEEEeecCCCCCCCCChhhcHHHHHH
Confidence            3477788888999999999999999998899999999999999999999999 599999999998652245899999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|++++++.      ..+++|+|+||||+|||++|+++               +.+|++.||+++|+|||
T Consensus        80 ~L~~~l~~~v~f~~d~~~~------~~~~~g~i~lLENlRF~~~E~~n---------------~~~fa~~La~l~DiyVn  138 (387)
T 6HXE_A           80 YLSKALGREVPLVSDYLNG------VDVKAGDIVLFENVRFNKGEKKN---------------ADELAKQYAALCDVFVM  138 (387)
T ss_dssp             HHHHHHTSCCCEESCCTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEEEE
T ss_pred             HHHHHhCCCCCccccccCC------ccCCCCcEEEEeCccCCCccccC---------------HHHHHHHHHHcccHhhc
Confidence            9999998779999865542      27889999999999999876532               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||+++||.|||+++++  +|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+||
T Consensus       139 DAF~~~HR~haS~vgi~~~l~~s~aG~l~~kEl~~L~~~l~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~a  218 (387)
T 6HXE_A          139 DAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDLLIVGGGIA  218 (387)
T ss_dssp             CCGGGTTCCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHTSCCSSEEEEEEESCTGGGHHHHHHHHTTCSEEEEEHHHH
T ss_pred             ccHhhcccccCchhhHhhccchhhHHHHHHHHHHHHHHHHcCCCCCeEEEEcCCCHHHHHHHHHHHHHHCCEEEEeChHH
Confidence            99999999999999998  6668999999999999999999999999999999999999999999999889999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|+ |+++|+|++|++..+.|+++++     +++|++|+|++|.+.+..++... ......+|++|+++||||+|+
T Consensus       219 ~tfL~a~-g~~vg~S~~e~~~~~~a~~il~-----~~ki~lP~D~vv~~~~~~~~~~~-~~~~~~ip~~~~~~DIGp~Ti  291 (387)
T 6HXE_A          219 DTFLAAA-GHPVGKSLYEPDLLDTARAIAA-----KVNVPLPTDVVVAKEFAESAEAT-VKLIADVAADDMILDIGPQTA  291 (387)
T ss_dssp             HHHHHHT-TCCCCSSCCCGGGHHHHHHHHH-----HSBCCCCSEEEEESCSSTTCCCE-EEEGGGCCTTCEEEEECHHHH
T ss_pred             HHHHHHc-CCCCCccccChhHHHHHHHHHH-----cCcccccccEEEchhhhccccce-EEehhhcCCCceeecCCHHHH
Confidence            9999998 8899999999888888888864     58999999999998754322110 111237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       292 ~~~~~~I~~aktI~wNGP~G~~E~~~f~~GT~~i~~al~~~---~a~~ivGGGdT~~~~~~~g~~~~~s~vSTGGGA~Le  368 (387)
T 6HXE_A          292 EHFAQLLKTSKTILWNGPVGVFEFDQFGNGTKVLAKAIADS---AAFSIAGGGDTLAAIDKYGVADQISQISTGGGAFLE  368 (387)
T ss_dssp             HHHHHHHHHCSEEEEECCSSCTTSGGGCHHHHHHHHHHHHC---SSEEEEESHHHHHHHHHHTCGGGSSEEECCHHHHHH
T ss_pred             HHHHHHHHcCCeEEEcCCCCccccCccCcHHHHHHHHHHhc---CCeEEEcCHHHHHHHHHhCCCccceEEEcchhHHHH
Confidence            99999999999999999999999888999999999999762   689999999999989988988889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|+.||||++|++
T Consensus       369 ~L~G~~LPgl~aL~~  383 (387)
T 6HXE_A          369 FVEGKVLPAVEVLES  383 (387)
T ss_dssp             HHTTCCCHHHHHHHH
T ss_pred             HHcCCCCchHHHHHH
Confidence            999999999999985


No 18
>4NG4_B Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, TRANSFERASE; HET: ADP; 2.78A {Coxiella burnetii}
Probab=100.00  E-value=4.7e-108  Score=829.99  Aligned_cols=389  Identities=41%  Similarity=0.687  Sum_probs=351.1  Template_Neff=6.400

Q NP_000282.1       1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         1 ~~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      |+...++++++.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+|
T Consensus         9 ~~~~~~~~~~~~~l~gk~vlvR~D~NVp~~~~~i~dd~Ri~~~lpTI~~Ll~~ga-kvvl~sHlGrP~~~~~~~~~Sl~~   87 (404)
T 4NG4_B            9 MKALPFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKA-RVMILSHLGRPEEGKFEKEFSLAP   87 (404)
T ss_dssp             ----CCCBGGGSCCTTCEEEEEECCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEEECCSCCCTTCCCGGGCSHH
T ss_pred             ccccccccccccccCCCEEEEEeecCccccCCccCCcHHHHHHHHHHHHHHHCCC-eEEEEeeccCcCCCCCcccccHHH
Confidence            5666778887788999999999999999988899999999999999999999999 599999999998753246899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|++.      ..+++|+|+||||+|||++|+.+               +++|+++||+++|+
T Consensus        88 v~~~L~~~l~~~v~fv~d~~~~------~~~~~g~ilLLENlRf~~~E~~~---------------~~~fa~~La~l~Di  146 (404)
T 4NG4_B           88 VARLLSKKLNQKVPLINDWLKG------VAVEPGQAILCENVRFNKGENEN---------------NTELAKRMAELCDI  146 (404)
T ss_dssp             HHHHHHHHTC-CCCEESSGGGC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSE
T ss_pred             HHHHHHHHhCCCCCcccccccc------ccCCCCCEEEEeccccCCccccc---------------cHHHHHHHHhcccH
Confidence            9999999998779999999873      37889999999999999976532               36799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGG  238 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG  238 (417)
                      ||||||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|+|||
T Consensus       147 yVnDAF~~~HR~~aS~~gi~~~l~~~~aG~l~~kEl~~l~~~~~~p~~P~v~IlGG~Kv~dKi~li~~Ll~~~D~iligG  226 (404)
T 4NG4_B          147 FVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGG  226 (404)
T ss_dssp             EEECCGGGTTSCCCCCCCHHHHCSEEEECHHHHHHHHHHHHHHHSCCSSEEEEEEESCGGGTHHHHHHHHTTCSEEEEEE
T ss_pred             hhhcCHhHcccccccccchhhccchhhhhHHHHHHHHHHHHHHhCCCCCEEEEECCCCHHHHHHHHHHHHHhcCeEEEcC
Confidence            99999999999999999998  6658999999999999999999999999999999999999999999999999999999


Q NP_000282.1     239 GMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGP  318 (417)
Q Consensus       239 ~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp  318 (417)
                      +||++||+|+ |+++|+|++|++..+.|++++++|++++++|++|+|++|.+.+..++.. .......+|++|+++||||
T Consensus       227 ~~a~tFL~a~-g~~ig~S~~e~~~~~~a~~ll~~a~~~~~kI~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~lDIGp  304 (404)
T 4NG4_B          227 GIANTFLKAQ-GYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKA-TVKNIDAVTSNESIFDVGP  304 (404)
T ss_dssp             HHHHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHHTCBCCCCSEEEEESSCSTTSCC-EEEEGGGCCTTCEEEEECH
T ss_pred             HHHHHHHHHc-CCCcccccccchHHHHHHHHHHHHHHCCCCcCceeEEEEcccCCccccc-EeecccccCCCcccccCCH
Confidence            9999999998 8999999999999999999999999999999999999999875433221 1112247888999999999


Q NP_000282.1     319 ESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGA  398 (417)
Q Consensus       319 ~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA  398 (417)
                      +|++.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++++.++++||||||||
T Consensus       305 ~Ti~~~~~~I~~aktI~wnGp~G~~E~~~f~~GT~~i~~~l~~~---~a~sivGGGDT~~~~~~~~~~~~~~~vStgGgA  381 (404)
T 4NG4_B          305 NTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKS---TAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGA  381 (404)
T ss_dssp             HHHHHHHHHHHHCSEEEEESCSSCTTSSTTCHHHHHHHHHHHHS---CSEEEECCHHHHHHHHHTTCGGGSSEECCCTHH
T ss_pred             HHHHHHHHHHHhCCEEEEeCCCCcccchhHcHHHHHHHHHHHhC---CCCEEEccHHHHHHHHHCCCCcCceEEecccHH
Confidence            99999999999999999999999999888999999999999763   689999999999999989988889999999999


Q NP_000282.1     399 SLELLEGKVLPGVDALSN  416 (417)
Q Consensus       399 ~Le~L~G~~LPgl~aL~~  416 (417)
                      +||||+|++||||++|++
T Consensus       382 ~Le~L~G~~LPgl~aL~~  399 (404)
T 4NG4_B          382 FLEFLEGKILPAIKILTQ  399 (404)
T ss_dssp             HHHHHHTCCCHHHHHHHH
T ss_pred             HHHHHcCCCChHHHHHHH
Confidence            999999999999999986


No 19
>4NG4_C Phosphoglycerate kinase (E.C.2.7.2.3); phosphoglycerate kinase, TRANSFERASE; HET: ADP; 2.78A {Coxiella burnetii}
Probab=100.00  E-value=4.7e-108  Score=829.99  Aligned_cols=389  Identities=41%  Similarity=0.687  Sum_probs=348.3  Template_Neff=6.400

Q NP_000282.1       1 MSLSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEP   80 (417)
Q Consensus         1 ~~~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~   80 (417)
                      |+...++++++.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+|
T Consensus         9 ~~~~~~~~~~~~~l~gk~vlvR~D~NVp~~~~~i~dd~Ri~~~lpTI~~Ll~~ga-kvvl~sHlGrP~~~~~~~~~Sl~~   87 (404)
T 4NG4_C            9 MKALPFLSMSNLNLHNKRVMIREDLNVPMKNGKITNDERIVRALPTIQKAIEQKA-RVMILSHLGRPEEGKFEKEFSLAP   87 (404)
T ss_dssp             ----CCCBGGGSCCTTCEEEEEECCCCCEETTEESCCHHHHHHHHHHHHHHHTTC-EEEEEECCSCCCTTCCCGGGCSHH
T ss_pred             ccccccccccccccCCCEEEEEeecCccccCCccCCcHHHHHHHHHHHHHHHCCC-eEEEEeeccCcCCCCCcccccHHH
Confidence            5666778887788999999999999999988899999999999999999999999 599999999998753246899999


Q NP_000282.1      81 VAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDV  160 (417)
Q Consensus        81 va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~Di  160 (417)
                      |+++|+++|+.+|.|+++|++.      ..+++|+|+||||+|||++|+.+               +++|+++||+++|+
T Consensus        88 v~~~L~~~l~~~v~fv~d~~~~------~~~~~g~ilLLENlRf~~~E~~~---------------~~~fa~~La~l~Di  146 (404)
T 4NG4_C           88 VARLLSKKLNQKVPLINDWLKG------VAVEPGQAILCENVRFNKGENEN---------------NTELAKRMAELCDI  146 (404)
T ss_dssp             HHHHHHHHCC--CCEESSGGGC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSE
T ss_pred             HHHHHHHHhCCCCCcccccccc------ccCCCCCEEEEeccccCCccccc---------------cHHHHHHHHhcccH
Confidence            9999999998779999999873      37889999999999999976532               36799999999999


Q NP_000282.1     161 YVNDAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGG  238 (417)
Q Consensus       161 yVNDAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG  238 (417)
                      ||||||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|+|||
T Consensus       147 yVnDAF~~~HR~~aS~~gi~~~l~~~~aG~l~~kEl~~l~~~~~~p~~P~v~IlGG~Kv~dKi~li~~Ll~~~D~iligG  226 (404)
T 4NG4_C          147 FVMDAFATAHRAQASTAGVAAYAKLACAGPLLISEVEALSRALENPQKPLVAVVGGSKVSTKIHLLENLLDKVDQLIVGG  226 (404)
T ss_dssp             EEECCGGGTTSCCCCCCCHHHHCSEEEECHHHHHHHHHHHHHHHSCCSSEEEEEEESCGGGTHHHHHHHHTTCSEEEEEE
T ss_pred             hhhcCHhHcccccccccchhhccchhhhhHHHHHHHHHHHHHHhCCCCCEEEEECCCCHHHHHHHHHHHHHhcCeEEEcC
Confidence            99999999999999999998  6658999999999999999999999999999999999999999999999999999999


Q NP_000282.1     239 GMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGP  318 (417)
Q Consensus       239 ~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp  318 (417)
                      +||++||+|+ |+++|+|++|++..+.|++++++|++++++|++|+|++|.+.+..++.. .......+|++|+++||||
T Consensus       227 ~~a~tFL~a~-g~~ig~S~~e~~~~~~a~~ll~~a~~~~~kI~lP~D~vv~~~~~~~~~~-~~~~~~~i~~~~~~lDIGp  304 (404)
T 4NG4_C          227 GIANTFLKAQ-GYSIGKSLCENEWLDAAQQFWEKAAEKNVSLPLPVDVIVADELSEDAKA-TVKNIDAVTSNESIFDVGP  304 (404)
T ss_dssp             HHHHHHHHHT-TCCCTTCCCCGGGHHHHHHHHHHHHHHTCBCCCCSEEEEESSCSTTSCC-EEEEGGGCCTTCEEEEECH
T ss_pred             HHHHHHHHHc-CCCcccccccchHHHHHHHHHHHHHHCCCCcCceeEEEEcccCCccccc-EeecccccCCCcccccCCH
Confidence            9999999998 8999999999999999999999999999999999999999875433221 1112247888999999999


Q NP_000282.1     319 ESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGA  398 (417)
Q Consensus       319 ~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA  398 (417)
                      +|++.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++++.++++||||||||
T Consensus       305 ~Ti~~~~~~I~~aktI~wnGp~G~~E~~~f~~GT~~i~~~l~~~---~a~sivGGGDT~~~~~~~~~~~~~~~vStgGgA  381 (404)
T 4NG4_C          305 NTSATYAKLMAQAGTIVWNGPIGVFEIEAFSQGTRALAQAVAKS---TAYSIVGGGDTLAALDKFNLTDQMSYVSTAGGA  381 (404)
T ss_dssp             HHHHHHHHHHHHCSEEEEESCSSCTTSSGGGHHHHHHHHHHHHS---CSEEEECCHHHHHHHHHTTCGGGSSEECCCTHH
T ss_pred             HHHHHHHHHHHhCCEEEEeCCCCcccchhHcHHHHHHHHHHHhC---CCCEEEccHHHHHHHHHCCCCcCceEEecccHH
Confidence            99999999999999999999999999888999999999999763   689999999999999989988889999999999


Q NP_000282.1     399 SLELLEGKVLPGVDALSN  416 (417)
Q Consensus       399 ~Le~L~G~~LPgl~aL~~  416 (417)
                      +||||+|++||||++|++
T Consensus       382 ~Le~L~G~~LPgl~aL~~  399 (404)
T 4NG4_C          382 FLEFLEGKILPAIKILTQ  399 (404)
T ss_dssp             HHHHHHC--CHHHHHHHH
T ss_pred             HHHHHcCCCChHHHHHHH
Confidence            999999999999999986


No 20
>6I06_A Phosphoglycerate kinase (E.C.2.7.2.3); hinge binding, TRANSFERASE, kinase, glycolysis; 2.0A {Pseudomonas}
Probab=100.00  E-value=1e-107  Score=823.37  Aligned_cols=381  Identities=39%  Similarity=0.687  Sum_probs=326.8  Template_Neff=6.400

Q NP_000282.1       4 SNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAV   83 (417)
Q Consensus         4 ~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~   83 (417)
                      |.++++++.|++|||||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++..++.+||+||++
T Consensus         1 ~~~~~l~~~~l~gK~vlvR~D~NVPl~~~~i~d~~RI~~~lpTI~~L~~~ga-kvil~sHlGrP~g~~~~~~~Sl~~va~   79 (387)
T 6I06_A            1 MTVLKMTDLDLQGKRVLIREDLNVPVKDGVVTSDARILASLPTIKLALEKGA-AVMVCSHLGRPTEGEFSAENSLKPVAD   79 (387)
T ss_dssp             CCBGG--GSCCTTCEEEEECCCCCCBSSSCBSCCHHHHHHHHHHHHHHHTTC-EEEEECCCSCCCTTSCCGGGCSHHHHH
T ss_pred             CCCccCChHHcCCCEEEEEeecCcccCCCCCCCcHHHHHHHHHHHHHHHCCC-cEEEEeecCCCCCCCCCcccchHHHHH
Confidence            3467777788999999999999999998899999999999999999999999 599999999998652235799999999


Q NP_000282.1      84 ELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVN  163 (417)
Q Consensus        84 ~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVN  163 (417)
                      +|+++|+.+|.|+++++..      ..+++|+|+||||+|||++|+++               +.+|++.||+++|+|||
T Consensus        80 ~L~~~l~~~v~f~~~~~~~------~~l~~g~illLENlRF~~~E~~n---------------~~~fa~~La~l~DiyVn  138 (387)
T 6I06_A           80 YLSKALGREVPLVSDYLNG------VDVKAGDIVLFENVRFNKGEKKN---------------ADELAKQYAALCDVFVM  138 (387)
T ss_dssp             HHHHHHTSCCCEESCCTTC------CCCCTTCEEEECCGGGSTTTTTT---------------CHHHHHHHHHTCSEEEE
T ss_pred             HHHHHHCCCceecCCCCCC------ccCCCCcEEEEeCcccCCCcccC---------------CHHHHHHHHhhccHhhc
Confidence            9999998778999855442      26889999999999999876532               36799999999999999


Q NP_000282.1     164 DAFGTAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNEMIIGGGMA  241 (417)
Q Consensus       164 DAFg~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~iligG~~a  241 (417)
                      |||+++||.|||+++++  +|+++||++|++|+++|++++++|+||+++|+||+|++||+++|++|++++|.|++||+||
T Consensus       139 DAF~~~HR~~aS~vgi~~~lp~s~aG~l~~kEl~~L~~~~~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~iligG~~a  218 (387)
T 6I06_A          139 DAFGTAHRAEGSTHGVAKFAKVAAAGPLLAAELDALGKALGAPAKPMAAIVAGSKVSTKLDVLNSLSQICDLLIVGGGIA  218 (387)
T ss_dssp             CCGGGTTSCCCCCCCHHHHSSEEEECHHHHHHHHHHHHHHSSCCSSEEEEEEESCTGGG--HTCSEE------EEEHHHH
T ss_pred             ccHhhcccccccccccccCCCchhhhHHHHHHHHHHHHHHhCCCCCEEEEEcCCCHHHHHHHHHHHHHcCCEEEEcChHH
Confidence            99999999999999998  6668999999999999999999999999999999999999999999999889999999999


Q NP_000282.1     242 FTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDCGPESS  321 (417)
Q Consensus       242 ~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DIGp~Ti  321 (417)
                      |+||+|+ |+++|+|++|++..+.|+++++     +++|++|+|++|.+.+..+.... .....++|++|+++||||+|+
T Consensus       219 ~tfL~a~-g~~vg~S~~e~~~~~~a~~il~-----~~ki~lP~D~vv~~~~~~~~~~~-~~~~~~ip~~~~~~DIGp~Ti  291 (387)
T 6I06_A          219 DTFLAAA-GHPVGKSLYEPDLLDTARAIAA-----KVNVPLPTDVVVAKEFAESAEAT-VKLIADVAADDMILDIGPQTA  291 (387)
T ss_dssp             HHHHHHT-TCCCBSCCCCGGGHHHHHHHHH-----HSBCCCCSEEEEESCSSTTCCCE-ECCTTC-----EEEEECHHHH
T ss_pred             HHHHHHc-CCcccccccchhHHHHHHHHHh-----cCeEEcccCEEecccCCCCCCcc-eeccccCCCCceeecCCHHHH
Confidence            9999998 8889999999888888888764     68999999999998653321110 111237888999999999999


Q NP_000282.1     322 KKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGGGASLE  401 (417)
Q Consensus       322 ~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgGgA~Le  401 (417)
                      +.|+++|++|||||||||||+||+++|++||+++++++++.   ++++|+|||||+++++++|+.++++||||||||+||
T Consensus       292 ~~~~~~I~~aktI~wnGp~G~~E~~~f~~GT~~i~~ai~~~---~a~~ivGGGdT~~~~~~~g~~~~~~~vStgGGA~L~  368 (387)
T 6I06_A          292 EHFAQLLKTSKTILWNGPVGVFEFDQFGNGTKVLAKAIADS---AAFSIAGGGDTLAAIDKYGVADQISYISTGGGAFLE  368 (387)
T ss_dssp             HHHHHHHHTCSEEEEECCSBCTTSGGGCHHHHHHHHHHHHS---CSEEEEESHHHHHHHHHHTCGGGSSEEECCTHHHHH
T ss_pred             HHHHHHHHhCCEEEEeCCCChhcCCccchHHHHHHHHHHhC---CCcEEEcCHHHHHHHHHcCCccCcEEEEechHHHHH
Confidence            99999999999999999999999888999999999999762   689999999999999988988889999999999999


Q NP_000282.1     402 LLEGKVLPGVDALSN  416 (417)
Q Consensus       402 ~L~G~~LPgl~aL~~  416 (417)
                      ||+|++||||++|++
T Consensus       369 ~L~G~~LPgl~aL~~  383 (387)
T 6I06_A          369 FVEGKVLPAVEVLES  383 (387)
T ss_dssp             HHTTCCCHHHHHHHH
T ss_pred             HHcCCCCchHHHHhH
Confidence            999999999999975


No 21
>2CUN_A Phosphoglycerate kinase (E.C.2.7.2.3); Phosphoglycerate kinase, Structural Genomics, TANPAKU; HET: 3PG, MPD, GOL; 2.1A {Pyrococcus horikoshii}
Probab=100.00  E-value=3.4e-105  Score=811.02  Aligned_cols=387  Identities=33%  Similarity=0.531  Sum_probs=341.8  Template_Neff=6.500

Q NP_000282.1       8 TLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGVPMPDKYSLEPVAVELKS   87 (417)
Q Consensus         8 ~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~~~~~~~Sl~~va~~L~~   87 (417)
                      +++|.|++||+||||+|+|||+++++|.|++||++++|||+||+++|| +|||+||+|||+++.   .+|++||+++|++
T Consensus         3 ~~~~~~l~gK~vlvR~D~Nvpl~~~~i~d~~Ri~~~lpTI~~Ll~~ga-kvvl~sH~GrP~~~~---~~sl~~v~~~L~~   78 (410)
T 2CUN_A            3 RLEDFNFHNKTVFLRVDLNSPMKDGKIISDARFKAVLPTIRYLIESGA-KVVIGTHQGKPYSED---YTTTEEHARVLSE   78 (410)
T ss_dssp             BGGGSCCTTCEEEEECCCCCCEETTEECCCHHHHHTHHHHHHHHHTTC-EEEEECCCSCTTCTT---CCCSHHHHHHHHH
T ss_pred             ccccccCCCCEEEEEeeCCCcccCCCCCCcHHHHHHHHHHHHHHHCCC-cEEEEeccCCCCCCC---CCCHHHHHHHHHH
Confidence            456678999999999999999998899999999999999999999999 599999999998753   6899999999999


Q NP_000282.1      88 LLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRASLSKLGDVYVNDAFG  167 (417)
Q Consensus        88 ~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~LA~l~DiyVNDAFg  167 (417)
                      +|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|++++++        +++++..|++.||+++|+||||||+
T Consensus        79 ~l~~~v~f~~~~~g~~~~~~i~~~~~g~illLENlRF~~~E~~~~~~--------~~~~~~~fa~~La~l~DiyVnDAF~  150 (410)
T 2CUN_A           79 LLDQHVEYIEDIFGRYAREKIKELKSGEVAILENLRFSAEEVKNKPI--------EECEKTFLVKKLSKVIDYVVNDAFA  150 (410)
T ss_dssp             HHTSCEEECSCSSSHHHHHHHHTCCTTCEEECSCGGGBTTTTSCCCH--------HHHTTSHHHHHHHTTCSEEEECCGG
T ss_pred             HHcCcEEehhhccChhHHHHHHHccCCCEEEEeccccchhHhcCCCh--------hHhHHHHHHHHHhccCCEEEecccc
Confidence            99877999999999888888899999999999999999977643110        0112356999999999999999999


Q NP_000282.1     168 TAHRAHSSMVGVN--LPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLD--KVNEMIIGGGMAFT  243 (417)
Q Consensus       168 ~aHR~~aS~~gi~--l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~--~~D~iligG~~a~t  243 (417)
                      ++||.|||+++++  +| ++||++|++||++|++++++|+||+++|+||+|++||+++|++|++  +||.|++||+||++
T Consensus       151 ~~HR~~aS~vgi~~~lp-s~aG~l~~kEl~~L~~~~~~p~rP~v~IlGG~KvsdKi~li~~Ll~~~~vD~IligG~~a~~  229 (410)
T 2CUN_A          151 TAHRSQPSLVGFARIKP-MIMGFLMEKEIEALMRAYYSKDSPKIYVLGGAKVEDSLKVVENVLRRERADLVLTGGLVANV  229 (410)
T ss_dssp             GTTCCCHHHHTTTTTSC-EEECHHHHHHHHHHHHHHTCCCSCEEEEECSSCHHHHHHHHHHHHHTTSCSEEEECHHHHHH
T ss_pred             cccCCCcchhhHHhhch-HHhcHHHHHHHHHHHHHHhCCCCCcEEEECCCCHHHHHHHHHHHHHHHhCCEEEEchhHHHH
Confidence            9999999999998  66 8999999999999999999999999999999999999999999996  78999999999999


Q NP_000282.1     244 FLKVLNNMEIGTSLFDEE-------GAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMGLDC  316 (417)
Q Consensus       244 fl~a~~g~~ig~s~~e~~-------~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~~DI  316 (417)
                      ||+|+ |+++|+|++|++       ..+.|+++++.   ++++|++|+||+|.++... ...........+|++|+++||
T Consensus       230 fL~a~-g~~ig~s~~e~~~~~~~~~~~~~a~~il~~---~~~~I~lPvD~~v~~~~~~-~~~~~~~~~~~ip~~~~~~DI  304 (410)
T 2CUN_A          230 FTLAK-GFDLGRKNVEFMKKKGLLDYVKHAEEILDE---FYPYIRTPVDFAVDYKGER-VEIDLLSENRGLLHQYQIMDI  304 (410)
T ss_dssp             HHHHH-TCCCCHHHHHHHHTTTGGGGHHHHHHHHHH---HGGGEECCSEEEEEETTEE-EEEESSSGGGGGGGTSCEEEE
T ss_pred             HHHHc-CCCCCcchHHHhHhhCHHHHHHHHHHHHHH---HCCccccceeEEecCCCCc-ceeeeeccccCCCCCceeecC
Confidence            99998 899999987763       34555555542   6889999999999886432 111011122478899999999


Q NP_000282.1     317 GPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVSTGG  396 (417)
Q Consensus       317 Gp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vStgG  396 (417)
                      ||+|++.|+++|++|||||||||||+||+++|++||++++++++++   ++++|+|||||+++++++|+. +++||||||
T Consensus       305 Gp~Ti~~~~~~I~~aktI~wnGP~G~~E~e~f~~GT~~i~~ai~~~---~a~~vvGGGdT~~~~~~~g~~-~~s~vStgG  380 (410)
T 2CUN_A          305 GKRTAEKYREILMKARIIVANGPMGVFEREEFAIGTVEVFKAIADS---PAFSVLGGGHSIASIQKYGIT-GITHISTGG  380 (410)
T ss_dssp             CHHHHHHHHHHHHTCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHS---SSEEEEECGGGGGGGGGSCCC-CCSEECSCS
T ss_pred             CHHHHHHHHHHHhhCCEEEEeCCCCcccchhhchhHHHHHHHHHcC---CCEEEEecHHHHHHHHHhCCC-CcEEEEecc
Confidence            9999999999999999999999999999888999999999999763   689999999999999888875 799999999


Q NP_000282.1     397 GASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       397 gA~Le~L~G~~LPgl~aL~~  416 (417)
                      ||+||||+|+.||||++|++
T Consensus       381 gA~Le~L~G~~LPgl~aL~~  400 (410)
T 2CUN_A          381 GAMLSFFAGEELPVLRALQI  400 (410)
T ss_dssp             HHHHHHHTTCCCHHHHHHHH
T ss_pred             hHHHHHHcCCCChHHHHHHH
Confidence            99999999999999999975


No 22
>1FW8_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); phosphotransferase, kinase, phosphoglycerate kinase, glycolysis; HET: GOL; 2.3A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=100.00  E-value=8.8e-90  Score=698.26  Aligned_cols=342  Identities=68%  Similarity=1.065  Sum_probs=299.2  Template_Neff=6.400

Q NP_000282.1      74 DKYSLEPVAVELKSLLGKDVLFLKDCVGPEVEKACANPAAGSVILLENLRFHVEEEGKGKDASGNKVKAEPAKIEAFRAS  153 (417)
Q Consensus        74 ~~~Sl~~va~~L~~~l~~~v~f~~~~~~~~~~~~~~~l~~g~i~lLENlRf~~~E~~~~~~~~~~~~~~~~~~~~~fa~~  153 (417)
                      +.+||+||+++|+++|+.+|.|+++|+|+++.+.++.+++|+|+||||+|||++|+++.++ ++.+.+++++++.+|++.
T Consensus         2 ~~~Sl~pva~~L~~ll~~~V~f~~d~~g~~~~~~i~~~~~g~IllLENlRF~~~E~~~~~~-n~~~~~~~~~~~~~fa~~   80 (416)
T 1FW8_A            2 SKYSLAPVAKELQSLLGKDVTFLNDCVGPEVEAAVKASAPGSVILLENLRYHIEEEGSRKV-DGQKVKASKEDVQKFRHE   80 (416)
T ss_dssp             CTTCSHHHHHHHHHHHTSCEEECSCSSSHHHHHHHHTSCTTEEEECCCGGGSHHHHSEEEE-TTEEEECCHHHHHHHHHH
T ss_pred             CCccHHHHHHHHHHHHCCceeeccCCCCHHHHHHHHhcCCCCEEEEecceecccccccccc-CCcccccCHHHHHHHHHH
Confidence            3689999999999999877999999999888888899999999999999999977632100 000001112234789999


Q NP_000282.1     154 LSKLGDVYVNDAFGTAHRAHSSMVGVNLPQKAGGFLMKKELNYFAKALESPERPFLAILGGAKVADKIQLINNMLDKVNE  233 (417)
Q Consensus       154 LA~l~DiyVNDAFg~aHR~~aS~~gi~l~~~~aG~ll~kEl~~l~~~l~~p~rP~v~IiGGaKv~dKi~~i~~Ll~~~D~  233 (417)
                      ||+++|+|||||||++||.|||++++++|+++||++|++||++|++++++|+||+++|+||+|++||+++|++|+++||.
T Consensus        81 La~l~diyVnDAFg~~HR~~aS~vgi~lp~s~aG~ll~kEi~~L~kil~~p~rP~v~IlGGaKv~dKi~~i~~Ll~~~D~  160 (416)
T 1FW8_A           81 LSSLADVYINDAFGTAHRAHSSMVGFDLPQRAAGFLLEKELKYFGKALENPTRPFLAILGGAKVADKIQLIDNLLDKVDS  160 (416)
T ss_dssp             HHTTCSEEEECCGGGTTSCCHHHHCCCCSCEEECHHHHHHHHHHHHHHHSCCSSEEEEEECSCSTTTHHHHHHHHTTCSE
T ss_pred             HHhhCCeEeecccccCCccccCcccCCCchhhhcHHHHHHHHHHHHHhhCCCCCEEEEEcCCCHHHHHHHHHHHHHhcCE
Confidence            99999999999999999999999999976589999999999999999999999999999999999999999999999999


Q NP_000282.1     234 MIIGGGMAFTFLKVLNNMEIGTSLFDEEGAKIVKDLMSKAEKNGVKITLPVDFVTADKFDENAKTGQATVASGIPAGWMG  313 (417)
Q Consensus       234 iligG~~a~tfl~a~~g~~ig~s~~e~~~~~~a~~il~~a~~~~~~i~lP~D~~v~~~~~~~~~~~~~~~~~~i~~~~~~  313 (417)
                      |++||+|||+||+|++++++|+|++|++..+.|++++++|+.++++|+||+|++|.+.+..+.....+...+.+|++|++
T Consensus       161 IligG~~a~tfL~a~~~~~iG~S~~e~~~~~~a~~il~~a~~~~~ki~LP~D~vv~~~~~~~~~~~~~~~~~~i~~~~~i  240 (416)
T 1FW8_A          161 IIIGGGMAFTFKKVLENTEIGDSIFDKAGAEIVPKLMEKAKAKGVEVVLPVDFIIADAFSADANTKTVTDKEGIPAGWQG  240 (416)
T ss_dssp             EEEEGGGHHHHHHHHSCCCCCSCCCCHHHHHHHHHHHHHHHHHTCEEECCSEEEEESSSSTTCCEEEEETTTCCCTTCEE
T ss_pred             EEeCchHHHHHHHHhCCCccCccccchhhhhHHHHHHHHHHHcCCeEEeeeeEEEeccccCCCCCceeeccCCCCCCCcc
Confidence            99999999999999755689999999988999999999988999999999999998865322211111122378899999


Q NP_000282.1     314 LDCGPESSKKYAEAVTRAKQIVWNGPVGVFEWEAFARGTKALMDEVVKATSRGCITIIGGGDTATCCAKWNTEDKVSHVS  393 (417)
Q Consensus       314 ~DIGp~Ti~~~~~~I~~aktI~WnGp~G~~E~~~f~~GT~~l~~al~~~~~~~~~~ivGGGdT~~~~~~~g~~~~~~~vS  393 (417)
                      +||||+|++.|.+.|++|||||||||||+||.++|++||+++++++++++.+++++|+|||||+++++++|+.++++|||
T Consensus       241 lDIGp~Ti~~~~~~I~~aktI~wnGP~G~~E~~~f~~GT~~i~~ai~~~~~~~a~~ivGGGdT~~~~~~~g~~~~~s~vS  320 (416)
T 1FW8_A          241 LDNGPESRKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTATVAKKYGVTDKISHVS  320 (416)
T ss_dssp             EEECHHHHHHHHHHHHHCSEEEEESCSSCTTSGGGCHHHHHHHHHHHHHHHTTCEEEECTTHHHHHHHHTTCGGGSSEEC
T ss_pred             cccCHHHHHHHHHHHHcCCEEEEcCCCCcccccccChHHHHHHHHHHHHhcCCCeEEEechhHHHHHHHhCCCCCceEEe
Confidence            99999999999999999999999999999998889999999999997632236899999999999998889878899999


Q NP_000282.1     394 TGGGASLELLEGKVLPGVDALSN  416 (417)
Q Consensus       394 tgGgA~Le~L~G~~LPgl~aL~~  416 (417)
                      |||||+||||+|+.||||++|++
T Consensus       321 TGGGA~Le~L~Gk~LPgieaL~~  343 (416)
T 1FW8_A          321 TGGGASLELLEGKELPGVAFLSE  343 (416)
T ss_dssp             SCSHHHHHHHTTCCCHHHHTSCS
T ss_pred             cCchHHHHHHcCCCCCceeehhh
Confidence            99999999999999999999985


No 23
>1FW8_A PHOSPHOGLYCERATE KINASE (E.C.2.7.2.3); phosphotransferase, kinase, phosphoglycerate kinase, glycolysis; HET: GOL; 2.3A {Saccharomyces cerevisiae} SCOP: c.86.1.1
Probab=99.28  E-value=3.2e-16  Score=156.69  Aligned_cols=68  Identities=57%  Similarity=0.940  Sum_probs=61.4  Template_Neff=6.400

Q NP_000282.1       3 LSNKLTLDKLDVKGKRVVMRVDFNVPMKNNQITNNQRIKAAVPSIKFCLDNGAKSVVLMSHLGRPDGV   70 (417)
Q Consensus         3 ~~~~~~i~~~~l~gK~VlvRvD~NVPl~~~~i~d~~RI~~~lpTI~~Ll~~gak~vil~SHlGRP~g~   70 (417)
                      ++.++++++.+++|||||||+|+|||+++++|.|++||++++|||+||+++||++||++||+|||+++
T Consensus       347 ~~~~~~~~~~~~~~k~vl~R~D~nvp~~~~~i~d~~Ri~~~~~ti~~l~~~~~~~vii~sH~grp~~~  414 (416)
T 1FW8_A          347 LSSKLSVQDLDLKDKRVFIRVDFNVPLDGKKITSNQRIVAALPTIKYVLEHHPRYVVLASHLGRPNGE  414 (416)
T ss_dssp             SSCSCBGGGSCCTTCEEEEECCCCCCBSSSSBSCTHHHHHHHHHHHHHHHTCCSEEEEECCCSCCCSS
T ss_pred             ccccccccccccCCCEEEEEeecCCCCCCCCcCCCHHHHhHHHHHHHHHHcCCCEEEEeeccCCCCCC
Confidence            45567777788999999999999999988899999999999999999999998449999999999875


No 24
>2Q33_B D-MONELLIN CHAIN A, D-MONELLIN CHAIN; ALPHA/BETA, ALL-D PROTEIN, DE NOVO; 1.8A {N/A}
Probab=34.33  E-value=5.9  Score=24.60  Aligned_cols=11  Identities=36%  Similarity=0.761  Sum_probs=9.2  Template_Neff=1.000

Q NP_000282.1     310 GWMGLDCGPES  320 (417)
Q Consensus       310 ~~~~~DIGp~T  320 (417)
                      .|.++||||-|
T Consensus         2 eweiidigpft   12 (48)
T 2Q33_B            2 EWEIIDIGPFT   12 (48)
Confidence            58899999955


Query         NP_000290.2
Match_columns 747
No_of_seqs    3849 out of 40250
Neff          6.23432
Searched_HMMs 998
Date          Fri Jul 24 20:45:58 2020
Command       /home/guerler/hh-suite/build/bin/hhblits -i /home/guerler/human/fasta/NP_00/NP_000290.2.fasta -d /home/guerler/pdb70/pdb70 -o /home/guerler/human/hhr/NP_00/NP_000290.2.hhr 

 No Hit                             Prob E-value P-value  Score    SS Cols Query HMM  Template HMM
  1 1XM9_A plakophilin 1  Plakophi  99.7 6.3E-22 7.3E-26  206.9   0.0  453  246-719     3-455 (457)
  2 3L6X_A Catenin delta-1, E-cadh  99.4 1.1E-17 1.2E-21  185.5   0.0  438  245-729    48-492 (584)
  3 5D5K_C Importin subunit alpha-  98.6 1.1E-11 1.4E-15  126.2   0.0  369  243-713    11-386 (466)
  4 3NMZ_A APC variant protein, Rh  98.6 1.3E-11 1.4E-15  129.0   0.0  381  238-715    25-452 (458)
  5 4UAF_B Importin alpha 1 import  98.5 1.3E-11 1.6E-15  125.7   0.0  369  243-713    11-386 (466)
  6 4U5L_A deltaIBB-importin-alpha  98.5 1.7E-11   2E-15  123.0   0.0  360  246-712    49-425 (426)
  7 6SA7_B DARPin-Armadillo fusion  98.5 2.5E-11 2.9E-15  127.0   0.0  136  244-380   172-309 (510)
  8 4RV1_D Engineered Protein OR49  98.5 2.7E-11 3.2E-15  120.8   0.0  362  247-715     4-369 (420)
  9 6S9O_F designed Armadillo repe  98.5 2.8E-11 3.3E-15  117.9   0.0  167  545-724   170-338 (344)
 10 5MFD_C YIIIM''6AII, Capsid dec  98.5   3E-11 3.5E-15  116.2   0.0  318  246-712     5-326 (328)
 11 4MZ6_E Deoxyuridine 5'-triphos  98.5 3.5E-11   4E-15  125.0   0.0  368  244-713    56-430 (509)
 12 5UMZ_B Importin subunit alpha-  98.5 3.5E-11   4E-15  125.0   0.0  368  244-713    56-430 (509)
 13 2JDQ_A IMPORTIN ALPHA-1 SUBUNI  98.4 3.6E-11 4.2E-15  122.1   0.0  367  244-716    19-393 (450)
 14 4E4V_A Importin subunit alpha-  98.4 3.6E-11 4.2E-15  124.3   0.0  364  246-716    76-456 (485)
 15 4B18_A IMPORTIN SUBUNIT ALPHA-  98.4   4E-11 4.7E-15  121.6   0.0  368  244-717    16-391 (447)
 16 4XZR_B Heh1-NLS, Kap60; karyop  98.4 4.3E-11   5E-15  119.8   0.0  363  248-717     4-375 (423)
 17 5XZX_A Importin subunit alpha-  98.4 4.3E-11 5.1E-15  119.5   0.0  133  247-380     4-140 (416)
 18 1JDH_A BETA-CATENIN, hTcf-4; B  98.4 4.4E-11 5.2E-15  123.9   0.0  378  245-726   101-502 (529)
 19 3IFQ_A plakoglobin, E-cadherin  98.4 4.5E-11 5.3E-15  124.5   0.0  381  246-726   104-503 (553)
 20 4UAD_A Importin alpha import a  98.4   6E-11   7E-15  121.8   0.0  372  246-723    68-456 (479)
 21 5ZHX_D Rap1 GTPase-GDP dissoci  98.4 6.3E-11 7.5E-15  120.9   0.0  407  246-727    19-458 (487)
 22 1EE4_A KARYOPHERIN ALPHA; ARM   98.4 8.2E-11 9.6E-15  117.7   0.0  364  247-717     3-375 (423)
 23 1EE4_B KARYOPHERIN ALPHA; ARM   98.4 8.2E-11 9.6E-15  117.7   0.0  364  247-717     3-375 (423)
 24 4EV8_A Catenin beta-1; mouse c  98.3 9.8E-11 1.2E-14  121.5   0.0  382  246-727   103-504 (538)
 25 4RXH_B Importin subunit alpha,  98.3 1.1E-10 1.2E-14  121.7   0.0  365  246-716    72-457 (495)
 26 4BQK_A IMPORTIN SUBUNIT ALPHA-  98.3 1.2E-10 1.3E-14  118.5   0.0  366  246-716    46-427 (456)
 27 6BW9_A Importin subunit alpha-  98.3 1.3E-10 1.5E-14  118.5   0.0  366  246-717    53-428 (459)
 28 1WA5_B GTP-BINDING NUCLEAR PRO  98.3 1.9E-10 2.2E-14  121.4   0.0  134  245-379   173-308 (530)
 29 5XGC_A Rap1 GTPase-GDP dissoci  98.3   2E-10 2.3E-14  117.7   0.0  409  246-729    35-476 (503)
 30 4BPL_A IMPORTIN SUBUNIT ALPHA-  98.2 2.4E-10 2.9E-14  115.9   0.0  367  246-717    44-426 (454)
 31 4B8J_A IMPORTIN SUBUNIT ALPHA-  98.2 2.6E-10 2.9E-14  120.0   0.0  367  246-717   118-500 (528)
 32 5T94_B Guanine nucleotide exch  98.2 2.9E-10 3.3E-14  120.5   0.0  364  246-716   131-513 (542)
 33 4TNM_A Importin-alpha3 / MOS6;  98.2 3.2E-10 3.7E-14  119.6   0.0  369  246-719   119-504 (531)
 34 5TBK_C Importin subunit alpha-  98.2 3.4E-10 3.8E-14  119.3   0.0  366  245-716    71-443 (521)
 35 5TBK_D Importin subunit alpha-  98.2 3.4E-10 3.8E-14  119.3   0.0  366  245-716    71-443 (521)
 36 2Z6G_A B-catenin; Full-Length,  98.1 6.4E-10 6.8E-14  126.7   0.0  381  245-725   234-634 (780)
 37 1JDH_A BETA-CATENIN, hTcf-4; B  98.1 6.1E-10 7.2E-14  115.0   0.0  326  286-717    16-343 (529)
 38 2Z6H_A Catenin beta-1; Beta-Ca  98.1 7.3E-10 8.1E-14  121.3   0.0  378  246-673    99-530 (644)
 39 6SA8_A ring-like DARPin-Armadi  98.1 7.7E-10 8.7E-14  121.2   0.0  342  244-691   177-522 (671)
 40 4RXH_B Importin subunit alpha,  98.1 1.2E-09 1.4E-13  113.4   0.0  157  545-714   196-354 (495)
 41 5XJG_A Vacuolar protein 8, Nuc  98.0 1.3E-09 1.5E-13  111.8   0.0  133  246-380   159-293 (506)
 42 6KBM_A Vacuolar protein 8, Aut  98.0 1.3E-09 1.5E-13  111.8   0.0  133  246-380   159-293 (506)
 43 4TNM_A Importin-alpha3 / MOS6;  98.0   2E-09 2.3E-13  113.3   0.0  158  545-714   243-402 (531)
 44 6KBN_A Vacuolar protein 8, Aut  98.0 2.1E-09 2.5E-13  112.9   0.0  133  246-380   153-287 (563)
 45 6KBN_C Vacuolar protein 8, Aut  98.0 2.1E-09 2.5E-13  112.9   0.0  133  246-380   153-287 (563)
 46 4EV8_A Catenin beta-1; mouse c  98.0 2.1E-09 2.5E-13  111.1   0.0  323  286-716    17-343 (538)
 47 4BPL_A IMPORTIN SUBUNIT ALPHA-  98.0 2.2E-09 2.5E-13  108.6   0.0  158  545-714   168-327 (454)
 48 4PLS_B Arm00010; PEPTIDE BINDI  98.0 2.5E-09 2.9E-13  100.1   0.0  112  247-359     3-114 (281)
 49 5Z8H_A Adenomatous polyposis c  98.0 2.6E-09   3E-13  104.9   0.0  123  258-380    92-219 (339)
 50 2Z6H_A Catenin beta-1; Beta-Ca  98.0 2.8E-09 3.1E-13  116.5   0.0  415  246-726    57-499 (644)
 51 5AEI_B DESIGNED ARMADILLO REPE  97.9 2.9E-09 3.4E-13   99.9   0.0  114  246-360     5-118 (286)
 52 4B8J_A IMPORTIN SUBUNIT ALPHA-  97.9 3.2E-09 3.7E-13  111.3   0.0  160  544-715   199-360 (528)
 53 4R10_A Protein humpback-2, Cad  97.9 4.1E-09 4.8E-13  110.8   0.0  417  245-725    73-531 (572)
 54 5XJG_A Vacuolar protein 8, Nuc  97.9 4.2E-09   5E-13  107.7   0.0  359  246-716    39-399 (506)
 55 6KBM_A Vacuolar protein 8, Aut  97.9 4.2E-09   5E-13  107.7   0.0  359  246-716    39-399 (506)
 56 5IZA_A Adenomatous polyposis c  97.9 4.5E-09   5E-13  105.1   0.0  297  236-625    23-335 (354)
 57 4R0Z_A Protein humpback-2; arm  97.9 5.4E-09 6.2E-13  112.3   0.0  401  246-718   115-565 (629)
 58 4R0Z_A Protein humpback-2; arm  97.9 5.5E-09 6.3E-13  112.2   0.0  418  245-726    73-532 (629)
 59 1XM9_A plakophilin 1  Plakophi  97.8 6.1E-09   7E-13  106.4   0.0  350  245-671    44-450 (457)
 60 4I2Z_A Protein UNC-45, Heat sh  97.8 7.3E-09 7.1E-13  122.5   0.0   69  247-316   648-716 (961)
 61 6SWY_5 Vacuolar import and deg  97.8 7.4E-09 7.2E-13  121.9   0.0  402  240-720   281-784 (921)
 62 5IZ8_A Adenomatous polyposis c  97.8 6.6E-09 7.4E-13  103.8   0.0  297  236-625    23-335 (354)
 63 3IFQ_A plakoglobin, E-cadherin  97.8 6.4E-09 7.5E-13  107.7   0.0  374  244-725    18-399 (553)
 64 4I2W_A Protein UNC-45, Heat sh  97.8 7.9E-09 7.7E-13  122.2   0.0   70  246-316   647-716 (961)
 65 4R10_A Protein humpback-2, Cad  97.8 8.7E-09   1E-12  108.2   0.0  398  246-715   115-562 (572)
 66 5T94_B Guanine nucleotide exch  97.8 9.3E-09 1.1E-12  108.5   0.0  159  544-715   254-414 (542)
 67 6KBN_A Vacuolar protein 8, Aut  97.8 9.2E-09 1.1E-12  107.8   0.0  358  245-714    32-391 (563)
 68 6KBN_C Vacuolar protein 8, Aut  97.8 9.2E-09 1.1E-12  107.8   0.0  358  245-714    32-391 (563)
 69 2Z6G_A B-catenin; Full-Length,  97.8 1.2E-08 1.3E-12  115.8   0.0  373  244-724   149-529 (780)
 70 5EWP_B Uncharacterized protein  97.7 1.3E-08 1.5E-12   96.8   0.0  118  263-381    60-181 (252)
 71 5XGC_A Rap1 GTPase-GDP dissoci  97.7 1.3E-08 1.6E-12  103.5   0.0  358  257-715     5-373 (503)
 72 6BW9_A Importin subunit alpha-  97.7 1.6E-08 1.9E-12  102.4   0.0  367  244-716     8-381 (459)
 73 5D5K_C Importin subunit alpha-  97.7   2E-08 2.4E-12  101.3   0.0  364  246-716    57-437 (466)
 74 4UAF_B Importin alpha 1 import  97.6 2.4E-08 2.9E-12  100.7   0.0  364  246-716    57-437 (466)
 75 3L6X_A Catenin delta-1, E-cadh  97.6 2.7E-08 2.9E-12  108.4   0.0  364  263-713    26-432 (584)
 76 4U5L_A deltaIBB-importin-alpha  97.6 2.9E-08 3.5E-12   98.5   0.0  367  245-713     5-378 (426)
 77 4MZ6_E Deoxyuridine 5'-triphos  97.6 3.4E-08   4E-12  101.6   0.0  364  246-716   101-481 (509)
 78 5UMZ_B Importin subunit alpha-  97.6 3.4E-08   4E-12  101.6   0.0  364  246-716   101-481 (509)
 79 5ZHX_D Rap1 GTPase-GDP dissoci  97.6 3.6E-08 4.2E-12   99.7   0.0  332  282-715    13-357 (487)
 80 3NOW_A SD10334p; Armadillo Rep  97.6 3.6E-08 4.2E-12  107.8   0.0  135  244-380   289-431 (810)
 81 4EV8_A Catenin beta-1; mouse c  97.5 4.1E-08 4.9E-12  100.9   0.0  137  245-381   267-409 (538)
 82 5Z8H_A Adenomatous polyposis c  97.5 4.4E-08   5E-12   95.7   0.0  161  544-716   162-332 (339)
 83 3SL9_B Catenin beta-1, B-cell   97.5 4.8E-08 5.5E-12   84.8   0.0  134  245-381    13-150 (167)
 84 4E4V_A Importin subunit alpha-  97.5   5E-08 5.7E-12   99.9   0.0  156  546-714   206-363 (485)
 85 1WA5_B GTP-BINDING NUCLEAR PRO  97.5 5.1E-08 5.8E-12  102.1   0.0  368  242-716    84-460 (530)
 86 1EE4_A KARYOPHERIN ALPHA; ARM   97.5 5.1E-08   6E-12   96.6   0.0  115  245-360    87-201 (423)
 87 1EE4_B KARYOPHERIN ALPHA; ARM   97.5 5.1E-08   6E-12   96.6   0.0  115  245-360    87-201 (423)
 88 4I2Z_A Protein UNC-45, Heat sh  97.5 6.2E-08   6E-12  114.3   0.0  431  248-725   443-904 (961)
 89 5XZX_A Importin subunit alpha-  97.5 6.3E-08 7.4E-12   95.7   0.0  360  246-711    46-415 (416)
 90 5MFO_F YIIIM3AIII; Designed ar  97.5 6.9E-08 8.1E-12   85.3   0.0  134  246-380     5-140 (202)
 91 3SL9_E Catenin beta-1, B-cell   97.5 7.2E-08 8.3E-12   83.6   0.0  134  245-381    13-150 (167)
 92 3NOW_A SD10334p; Armadillo Rep  97.5 7.3E-08 8.5E-12  105.4   0.0  110  247-358     8-120 (810)
 93 5MFO_E YIIIM3AIII; Designed ar  97.4 7.9E-08 9.3E-12   84.9   0.0  134  246-380     5-140 (202)
 94 4XZR_B Heh1-NLS, Kap60; karyop  97.4 8.1E-08 9.6E-12   95.0   0.0  115  245-360    87-201 (423)
 95 3OPB_A SWI5-dependent HO expre  97.4 9.1E-08 9.6E-12  108.6   0.0  168  546-719   544-734 (778)
 96 4I2W_A Protein UNC-45, Heat sh  97.4   1E-07 9.8E-12  112.5   0.0  433  247-726   442-905 (961)
 97 3TT9_A Plakophilin-2; CELL ADH  97.4 9.1E-08   1E-11   88.5   0.0  221  245-487     8-232 (233)
 98 2Z6H_A Catenin beta-1; Beta-Ca  97.4 9.4E-08   1E-11  103.9   0.0  378  241-726    10-395 (644)
 99 4U2X_E eVP24, KPNA5C; eVP24, i  97.4 9.4E-08 1.1E-11   83.8   0.0  116  246-362     9-125 (175)
100 4RV1_D Engineered Protein OR49  97.4 9.1E-08 1.1E-11   94.3   0.0  363  246-715    45-411 (420)
101 4BQK_A IMPORTIN SUBUNIT ALPHA-  97.4 9.4E-08 1.1E-11   96.1   0.0  158  545-714   170-329 (456)
102 5TBK_C Importin subunit alpha-  97.4   1E-07 1.2E-11   99.7   0.0  160  544-715   196-357 (521)
103 5TBK_D Importin subunit alpha-  97.4   1E-07 1.2E-11   99.7   0.0  160  544-715   196-357 (521)
104 4U2X_F eVP24, KPNA5C; eVP24, i  97.4 1.2E-07 1.4E-11   83.0   0.0  116  246-362     9-125 (175)
105 4V3Q_A YIII_M4_AII; DE NOVO PR  97.4 1.2E-07 1.4E-11   87.0   0.0  113  247-360    10-122 (247)
106 3NMZ_A APC variant protein, Rh  97.3 1.5E-07 1.7E-11   97.0   0.0  136  245-380   243-389 (458)
107 3L6X_A Catenin delta-1, E-cadh  97.3 1.6E-07 1.7E-11  102.1   0.0  377  246-672    91-522 (584)
108 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  97.3 1.5E-07 1.8E-11   85.8   0.0  113  246-359     5-117 (243)
109 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  97.3 1.5E-07 1.8E-11   85.8   0.0  113  246-359     5-117 (243)
110 5VOZ_P V-type proton ATPase ca  97.3 2.1E-07 2.1E-11  101.0   0.0  134  246-382   124-281 (478)
111 5D80_H V-type proton ATPase ca  97.3 2.1E-07 2.1E-11  101.0   0.0  134  246-382   124-281 (478)
112 1JDH_A BETA-CATENIN, hTcf-4; B  97.3 1.9E-07 2.2E-11   95.6   0.0  138  245-382   266-409 (529)
113 2Z6G_A B-catenin; Full-Length,  97.3 2.2E-07 2.3E-11  105.1   0.0  353  245-671   276-664 (780)
114 1HO8_A VACUOLAR ATP SYNTHASE S  97.3 2.5E-07 2.5E-11  100.5   0.0  135  245-382   125-283 (480)
115 6S9O_F designed Armadillo repe  97.2 2.9E-07 3.4E-11   88.3   0.0  135  246-381   173-309 (344)
116 1XM9_A plakophilin 1  Plakophi  97.2 3.2E-07 3.6E-11   93.1   0.0  114  246-361   332-451 (457)
117 1XQS_B HSPBP1 protein, Heat sh  97.2 3.3E-07 3.7E-11   87.9   0.0  134  246-380    66-203 (280)
118 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  97.2 3.4E-07   4E-11   83.4   0.0  134  246-380    47-182 (243)
119 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  97.2 3.4E-07   4E-11   83.4   0.0  134  246-380    47-182 (243)
120 6SA6_A DARPin-Armadillo fusion  97.2 3.9E-07 4.4E-11   91.0   0.0  134  246-380   200-335 (397)
121 6SA8_A ring-like DARPin-Armadi  97.2   4E-07 4.5E-11   98.8   0.0  135  245-380   220-356 (671)
122 1XQR_A HspBP1 protein; armadil  97.1 4.4E-07 4.9E-11   88.9   0.0  134  246-380    82-219 (296)
123 4UAD_A Importin alpha import a  97.1 4.5E-07 5.3E-11   91.8   0.0  368  245-718    23-398 (479)
124 5MFD_C YIIIM''6AII, Capsid dec  97.1 6.1E-07 7.2E-11   84.8   0.0  114  246-360    89-202 (328)
125 6HB3_B Protein HGH1; solenoid   97.1   7E-07 7.2E-11   92.3   0.0  121  246-369    52-208 (369)
126 3OPB_A SWI5-dependent HO expre  97.1 7.2E-07 7.6E-11  100.9   0.0  156  546-711   605-776 (778)
127 4HXT_A De Novo Protein OR329;   97.0 7.7E-07 9.1E-11   80.9   0.0  113  247-360     4-116 (252)
128 3GQ2_A General vesicular trans  97.0 9.1E-07 9.4E-11   98.4   0.0  136  245-381    60-219 (651)
129 3GRL_A General vesicular trans  97.0 9.1E-07 9.4E-11   98.4   0.0  136  245-381    60-219 (651)
130 4HXT_A De Novo Protein OR329;   97.0 8.1E-07 9.6E-11   80.7   0.0  114  246-360    45-158 (252)
131 4PLS_B Arm00010; PEPTIDE BINDI  97.0 8.3E-07 9.9E-11   82.1   0.0  114  246-360    44-157 (281)
132 5IZA_A Adenomatous polyposis c  97.0 9.5E-07 1.1E-10   87.4   0.0  114  245-358   127-246 (354)
133 5IZ8_A Adenomatous polyposis c  97.0   1E-06 1.1E-10   87.2   0.0  113  246-358   128-246 (354)
134 6SA7_B DARPin-Armadillo fusion  97.0 1.1E-06 1.2E-10   90.6   0.0  135  246-381   342-478 (510)
135 4V3Q_A YIII_M4_AII; DE NOVO PR  97.0 1.1E-06 1.3E-10   80.3   0.0  135  245-380    92-228 (247)
136 5Z8H_A Adenomatous polyposis c  96.9 1.2E-06 1.4E-10   85.0   0.0  134  245-379   122-267 (339)
137 5AEI_B DESIGNED ARMADILLO REPE  96.9 1.4E-06 1.7E-10   80.6   0.0  112  246-358   173-284 (286)
138 5IZA_A Adenomatous polyposis c  96.9 1.5E-06 1.7E-10   85.8   0.0  124  258-381    97-225 (354)
139 5IZ8_A Adenomatous polyposis c  96.9 1.6E-06 1.8E-10   85.8   0.0  124  258-381    97-225 (354)
140 3NMZ_A APC variant protein, Rh  96.9 1.6E-06 1.8E-10   88.9   0.0  135  246-381   287-432 (458)
141 6SA7_B DARPin-Armadillo fusion  96.9 1.6E-06 1.9E-10   89.2   0.0  134  246-380   300-435 (510)
142 5TBK_C Importin subunit alpha-  96.9 1.7E-06 1.9E-10   90.0   0.0  367  246-718   115-491 (521)
143 5TBK_D Importin subunit alpha-  96.9 1.7E-06 1.9E-10   90.0   0.0  367  246-718   115-491 (521)
144 6HB1_A Protein HGH1; solenoid   96.9 1.8E-06 1.9E-10   89.0   0.0  169  547-723    51-256 (369)
145 6HB2_D Protein HGH1; solenoid   96.9 1.8E-06 1.9E-10   89.0   0.0  169  547-723    51-256 (369)
146 5MFD_C YIIIM''6AII, Capsid dec  96.8 1.8E-06 2.1E-10   81.5   0.0  114  246-360    47-160 (328)
147 6SA7_B DARPin-Armadillo fusion  96.8 1.8E-06 2.1E-10   88.8   0.0  115  246-361   384-498 (510)
148 6S9O_F designed Armadillo repe  96.8 2.5E-06 2.9E-10   81.5   0.0  115  245-360    46-160 (344)
149 1XM9_A plakophilin 1  Plakophi  96.8 2.5E-06 2.9E-10   86.1   0.0  167  543-716    82-316 (457)
150 4HXT_A De Novo Protein OR329;   96.8 2.5E-06 2.9E-10   77.3   0.0  114  246-360   129-242 (252)
151 6SA6_A DARPin-Armadillo fusion  96.7   3E-06 3.4E-10   84.2   0.0  132  248-380   160-293 (397)
152 3NMZ_A APC variant protein, Rh  96.7 3.3E-06 3.7E-10   86.5   0.0  135  246-380   190-340 (458)
153 6HB1_A Protein HGH1; solenoid   96.6 5.3E-06 5.5E-10   85.4   0.0   93  287-381     9-108 (369)
154 6HB2_D Protein HGH1; solenoid   96.6 5.3E-06 5.5E-10   85.4   0.0   93  287-381     9-108 (369)
155 2W3C_A GENERAL VESICULAR TRANS  96.6 5.7E-06 5.9E-10   90.0   0.0  135  246-381    71-213 (577)
156 4XZR_B Heh1-NLS, Kap60; karyop  96.6 5.2E-06 6.2E-10   81.4   0.0  114  246-360   172-285 (423)
157 3TT9_A Plakophilin-2; CELL ADH  96.6   6E-06 6.8E-10   75.6   0.0  136  246-382    53-206 (233)
158 6HB3_B Protein HGH1; solenoid   96.6 6.6E-06 6.8E-10   84.6   0.0   93  287-381     9-108 (369)
159 6SA8_A ring-like DARPin-Armadi  96.5 6.4E-06 7.1E-10   88.9   0.0  322  286-714   177-502 (671)
160 1EE4_A KARYOPHERIN ALPHA; ARM   96.5 6.8E-06 8.1E-10   80.5   0.0  114  246-360   214-327 (423)
161 1EE4_B KARYOPHERIN ALPHA; ARM   96.5 6.8E-06 8.1E-10   80.5   0.0  114  246-360   214-327 (423)
162 5KC2_B Phosphatidylinositol 3-  96.5 9.9E-06   1E-09   98.5   0.0  150  546-715   618-768 (1454)
163 4B18_A IMPORTIN SUBUNIT ALPHA-  96.4 8.9E-06   1E-09   80.7   0.0  366  245-716    61-443 (447)
164 1JDH_A BETA-CATENIN, hTcf-4; B  96.4   9E-06 1.1E-09   82.5   0.0  363  245-712   143-529 (529)
165 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  96.4 9.2E-06 1.1E-09   73.3   0.0  135  245-380    88-224 (243)
166 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  96.4 9.2E-06 1.1E-09   73.3   0.0  135  245-380    88-224 (243)
167 4MFU_A Beta-catenin-like prote  96.4 1.1E-05 1.1E-09   87.3   0.0  182  539-725    60-261 (490)
168 5AEI_B DESIGNED ARMADILLO REPE  96.4   1E-05 1.2E-09   74.6   0.0  134  246-380    89-224 (286)
169 4PLS_B Arm00010; PEPTIDE BINDI  96.4 1.1E-05 1.3E-09   74.1   0.0  111  246-357   170-280 (281)
170 4HM9_A Beta-catenin-like prote  96.4 1.4E-05 1.3E-09   88.6   0.0  181  539-725   138-339 (568)
171 3L6X_A Catenin delta-1, E-cadh  96.4 1.3E-05 1.4E-09   86.3   0.0  135  246-381   236-406 (584)
172 4U5L_A deltaIBB-importin-alpha  96.4 1.2E-05 1.4E-09   78.7   0.0  134  246-380   223-359 (426)
173 2JDQ_A IMPORTIN ALPHA-1 SUBUNI  96.3 1.3E-05 1.5E-09   79.6   0.0  366  245-716    64-446 (450)
174 3GQ2_A General vesicular trans  96.3 1.5E-05 1.5E-09   88.2   0.0  169  543-721   204-403 (651)
175 3GRL_A General vesicular trans  96.3 1.5E-05 1.5E-09   88.2   0.0  169  543-721   204-403 (651)
176 3TT9_A Plakophilin-2; CELL ADH  96.3 1.5E-05 1.7E-09   72.9   0.0  113  246-360    95-230 (233)
177 5D5K_C Importin subunit alpha-  96.3 1.5E-05 1.8E-09   79.2   0.0  113  246-359   273-386 (466)
178 4UAF_B Importin alpha 1 import  96.3 1.6E-05 1.8E-09   79.1   0.0  113  246-359   273-386 (466)
179 2JDQ_A IMPORTIN ALPHA-1 SUBUNI  96.2 1.8E-05 2.2E-09   78.4   0.0  134  246-380   235-371 (450)
180 3IFQ_A plakoglobin, E-cadherin  96.2 1.8E-05 2.2E-09   80.6   0.0  367  245-716   145-534 (553)
181 4BQK_A IMPORTIN SUBUNIT ALPHA-  96.2 1.9E-05 2.2E-09   78.5   0.0  116  245-360   172-287 (456)
182 4U5L_A deltaIBB-importin-alpha  96.2 2.2E-05 2.6E-09   76.7   0.0  115  245-360   180-294 (426)
183 4BPL_A IMPORTIN SUBUNIT ALPHA-  96.2 2.3E-05 2.7E-09   77.8   0.0  135  245-379   170-306 (454)
184 4MZ6_E Deoxyuridine 5'-triphos  96.1 2.6E-05 3.1E-09   79.0   0.0  113  246-359   317-430 (509)
185 5UMZ_B Importin subunit alpha-  96.1 2.6E-05 3.1E-09   79.0   0.0  113  246-359   317-430 (509)
186 4E4V_A Importin subunit alpha-  96.1 2.7E-05 3.1E-09   78.7   0.0  113  246-359   292-405 (485)
187 3GQ2_A General vesicular trans  96.1 3.4E-05 3.5E-09   85.2   0.0  176  543-726    56-255 (651)
188 3GRL_A General vesicular trans  96.1 3.4E-05 3.5E-09   85.2   0.0  176  543-726    56-255 (651)
189 4V3Q_A YIII_M4_AII; DE NOVO PR  96.0 3.4E-05   4E-09   69.7   0.0  112  246-358   135-246 (247)
190 4TNM_A Importin-alpha3 / MOS6;  96.0 3.5E-05   4E-09   79.5   0.0  136  245-380   245-382 (531)
191 4GMO_A Putative uncharacterize  95.9 5.4E-05 5.2E-09   85.2   0.0   94  245-339    34-129 (684)
192 4PLS_B Arm00010; PEPTIDE BINDI  95.9 4.9E-05 5.8E-09   69.4   0.0  134  246-380    86-221 (281)
193 5MFO_F YIIIM3AIII; Designed ar  95.9   5E-05 5.9E-09   65.8   0.0  112  246-358    89-200 (202)
194 2RU4_A Armadillo Repeat Protei  95.9 5.2E-05   6E-09   59.8   0.0  110  248-358     4-113 (115)
195 5AEI_B DESIGNED ARMADILLO REPE  95.9 5.1E-05 6.1E-09   69.5   0.0  114  246-360    47-160 (286)
196 5MFD_C YIIIM''6AII, Capsid dec  95.9 5.1E-05 6.1E-09   70.8   0.0  157  545-714   128-286 (328)
197 5MFO_E YIIIM3AIII; Designed ar  95.9 5.2E-05 6.2E-09   65.7   0.0  112  246-358    89-200 (202)
198 5D5K_C Importin subunit alpha-  95.8 5.5E-05 6.5E-09   74.9   0.0  158  544-714   138-302 (466)
199 1XQS_B HSPBP1 protein, Heat sh  95.8 5.9E-05 6.6E-09   71.4   0.0  116  246-362   109-225 (280)
200 4UAF_B Importin alpha 1 import  95.8 5.9E-05   7E-09   74.7   0.0  158  544-714   138-302 (466)
201 1XQR_A HspBP1 protein; armadil  95.8 6.4E-05   7E-09   72.7   0.0  116  246-362   125-241 (296)
202 6CRI_R Bone marrow stromal ant  95.8 6.2E-05 7.1E-09   78.2   0.0  151  547-721   414-577 (585)
203 6SA8_A ring-like DARPin-Armadi  95.8 6.8E-05 7.7E-09   80.4   0.0  136  245-381   262-399 (671)
204 5WBJ_A Regulatory-associated p  95.8 8.1E-05 7.9E-09   89.5   0.0  168  541-715   500-672 (1287)
205 5Z8H_A Adenomatous polyposis c  95.7 7.4E-05 8.5E-09   71.6   0.0  115  246-361   210-331 (339)
206 5WBK_A Regulatory-associated p  95.7 9.2E-05   9E-09   89.0   0.0  168  541-715   500-672 (1287)
207 6SA6_A DARPin-Armadillo fusion  95.7 8.4E-05 9.6E-09   73.2   0.0  135  245-380   241-377 (397)
208 2W3C_A GENERAL VESICULAR TRANS  95.6 0.00012 1.2E-08   79.1   0.0  136  246-382     9-168 (577)
209 6CRI_I Bone marrow stromal ant  95.6  0.0001 1.2E-08   74.8   0.0  106  244-360    72-177 (570)
210 1QBK_B STRUCTURE OF THE KARYOP  95.6 0.00011 1.3E-08   79.3   0.0  157  547-715   667-824 (890)
211 4P6Z_G BST2/tetherin, HIV-1 Vp  95.6 0.00012 1.3E-08   77.7   0.0  151  547-721   431-594 (627)
212 5MFI_B YIII(Dq.V2)4CqI, (KR)4;  95.5 0.00014 1.6E-08   65.0   0.0  112  246-358   131-242 (243)
213 5MFJ_B YIII(Dq.V2)4CqI, (KR)5;  95.5 0.00014 1.6E-08   65.0   0.0  112  246-358   131-242 (243)
214 5EWP_B Uncharacterized protein  95.4 0.00015 1.7E-08   67.3   0.0  134  246-380    87-233 (252)
215 4V3Q_A YIII_M4_AII; DE NOVO PR  95.4 0.00017   2E-08   64.8   0.0  134  246-380    51-186 (247)
216 3GQ2_A General vesicular trans  95.3 0.00022 2.3E-08   78.3   0.0  135  246-381   123-265 (651)
217 3GRL_A General vesicular trans  95.3 0.00022 2.3E-08   78.3   0.0  135  246-381   123-265 (651)
218 5AFF_A SYMPORTIN 1, RIBOSOMAL   95.2 0.00026 2.6E-08   78.8   0.0   94  245-339    12-107 (654)
219 6QH5_B AP-2 complex subunit al  95.2 0.00023 2.7E-08   73.0   0.0  107  243-360    84-190 (592)
220 3C2G_A Sys-1 protein, Pop-1 8-  95.2 0.00033 2.8E-08   77.7   0.0  189  260-486   185-412 (619)
221 4FDD_A Transportin-1, RNA-bind  95.1 0.00028 3.3E-08   75.3   0.0  157  547-715   629-786 (852)
222 4P6Z_B BST2/tetherin, HIV-1 Vp  95.0 0.00031 3.6E-08   72.5   0.0  106  244-360   101-206 (600)
223 2JKT_A AP-2 COMPLEX SUBUNIT AL  95.0 0.00032 3.7E-08   73.5   0.0  144  547-714   441-590 (623)
224 5IZ8_A Adenomatous polyposis c  95.0 0.00036 4.1E-08   67.8   0.0  162  543-716   166-337 (354)
225 5IZA_A Adenomatous polyposis c  94.9 0.00036 4.1E-08   67.8   0.0  162  543-716   166-337 (354)
226 5YVI_A Transportin-1, RNA-bind  94.9 0.00036 4.3E-08   74.5   0.0  156  547-714   645-801 (868)
227 6QH7_A AP-2 complex subunit al  94.9 0.00038 4.3E-08   73.0   0.0  108  242-360   108-217 (621)
228 1B3U_A PROTEIN PHOSPHATASE PP2  94.9  0.0004 4.8E-08   70.1   0.0  146  547-712   441-586 (588)
229 4HM9_A Beta-catenin-like prote  94.8 0.00057 5.4E-08   75.0   0.0  161  543-716   241-424 (568)
230 6QH5_A AP-2 complex subunit al  94.8 0.00048 5.5E-08   72.2   0.0  144  548-715   442-591 (621)
231 5MFO_F YIIIM3AIII; Designed ar  94.7 0.00052 6.2E-08   58.9   0.0  134  246-380    47-182 (202)
232 5MFO_E YIIIM3AIII; Designed ar  94.7 0.00054 6.3E-08   58.8   0.0  134  246-380    47-182 (202)
233 4MFU_A Beta-catenin-like prote  94.6 0.00067 6.6E-08   72.8   0.0  161  543-716   163-346 (490)
234 2NYL_A Protein phosphatase 2,   94.6 0.00059 7.1E-08   68.5   0.0  145  548-712   436-580 (582)
235 4U2X_F eVP24, KPNA5C; eVP24, i  94.4 0.00082 9.5E-08   57.1   0.0   73  246-318    51-124 (175)
236 3SL9_B Catenin beta-1, B-cell   94.3 0.00082 9.5E-08   56.5   0.0  110  246-357    56-166 (167)
237 4I5L_D PP2A A alpha subunit (9  94.3  0.0008 9.6E-08   67.6   0.0  110  246-359   239-349 (584)
238 4U2X_E eVP24, KPNA5C; eVP24, i  94.3 0.00091   1E-07   56.8   0.0   73  246-318    51-124 (175)
239 4UQI_B AP-2 COMPLEX SUBUNIT AL  94.2 0.00095 1.1E-07   70.3   0.0  106  244-360    85-190 (657)
240 5KC2_B Phosphatidylinositol 3-  94.0  0.0013 1.4E-07   79.1   0.0  155  544-715   506-689 (1454)
241 3SL9_E Catenin beta-1, B-cell   94.0  0.0012 1.4E-07   55.4   0.0  110  246-357    56-166 (167)
242 3VWA_B Cytoplasmic export prot  93.8  0.0017 1.8E-07   68.9   0.0  150  546-714   379-529 (560)
243 5DFZ_B Vacuolar protein sortin  93.7  0.0018 1.8E-07   77.7   0.0  155  546-719   608-762 (1460)
244 6HWP_A A3_bGFPD; alphaRep, art  93.7  0.0016 1.9E-07   62.8   0.0   91  245-358    23-113 (409)
245 3TT9_A Plakophilin-2; CELL ADH  93.7  0.0017 1.9E-07   58.2   0.0  169  542-716    47-232 (233)
246 3VWA_A Cytoplasmic export prot  93.6  0.0019   2E-07   68.6   0.0  152  545-715   378-530 (560)
247 1XQR_A HspBP1 protein; armadil  93.6  0.0019 2.1E-07   61.7   0.0  122  257-380    52-177 (296)
248 1XQS_B HSPBP1 protein, Heat sh  93.4  0.0023 2.6E-07   59.7   0.0  123  257-380    36-161 (280)
249 5VOZ_P V-type proton ATPase ca  93.3  0.0027 2.7E-07   67.5   0.0  330  290-714    78-475 (478)
250 5D80_H V-type proton ATPase ca  93.3  0.0027 2.7E-07   67.5   0.0  330  290-714    78-475 (478)
251 1F59_B IMPORTIN BETA-1/FXFG NU  93.3  0.0024 2.8E-07   62.2   0.0  154  549-713   261-437 (442)
252 6XTE_A Importin-5, antipain; h  93.2  0.0025 2.9E-07   70.4   0.0  153  548-714   358-521 (1096)
253 4HXT_A De Novo Protein OR329;   93.2  0.0025   3E-07   56.2   0.0  134  246-380    87-222 (252)
254 5IFE_C Splicing factor 3B subu  93.2  0.0029   3E-07   75.0   0.0  153  548-714   932-1087(1304)
255 6AHD_1 Pre-mRNA-processing-spl  93.2  0.0029   3E-07   75.0   0.0  153  548-714   932-1087(1304)
256 6QH5_B AP-2 complex subunit al  93.1  0.0027 3.1E-07   64.6   0.0  146  548-714   428-573 (592)
257 6EN4_C Splicing factor 3B subu  92.9  0.0031 3.6E-07   67.4   0.0  154  548-714   480-635 (852)
258 6SA6_A DARPin-Armadillo fusion  92.9  0.0032 3.7E-07   61.0   0.0  112  246-358   284-395 (397)
259 6FT5_A A3_A3; alphaRep, artifi  92.9  0.0032 3.7E-07   60.7   0.0   91  245-358    23-113 (409)
260 3C5W_A PP2A A subunit, PP2A C;  92.9  0.0032 3.8E-07   54.7   0.0  146  548-713    86-231 (232)
261 4LAC_A Serine/threonine-protei  92.9  0.0033 3.8E-07   56.3   0.0  110  545-670    31-140 (258)
262 4FDD_A Transportin-1, RNA-bind  92.6  0.0039 4.6E-07   65.8   0.0  150  548-712   360-511 (852)
263 5NR4_A CLIP-associating protei  92.6   0.004 4.6E-07   54.4   0.0  148  548-715    53-200 (230)
264 3C5W_A PP2A A subunit, PP2A C;  92.5  0.0041 4.8E-07   53.9   0.0  107  548-670     8-114 (232)
265 6XU2_A Importin-5, antipain; h  92.5  0.0042 4.9E-07   68.8   0.0  152  548-713   377-539 (1115)
266 4LAC_A Serine/threonine-protei  92.5  0.0043   5E-07   55.5   0.0  146  548-713   112-257 (258)
267 6EN4_C Splicing factor 3B subu  92.5  0.0043   5E-07   66.2   0.0  147  547-714   675-823 (852)
268 1QBK_B STRUCTURE OF THE KARYOP  92.4  0.0043 5.1E-07   66.1   0.0  151  548-713   398-550 (890)
269 6CRI_I Bone marrow stromal ant  92.4  0.0043 5.1E-07   62.1   0.0  145  548-714   415-560 (570)
270 2RU4_B Armadillo Repeat Protei  92.4  0.0045 5.2E-07   45.3   0.0   71  287-358    12-82  (84)
271 4L7M_A Putative uncharacterize  92.3  0.0047 5.5E-07   55.6   0.0   75  545-625    35-109 (269)
272 5WBJ_A Regulatory-associated p  92.2  0.0059 5.8E-07   72.7   0.0  100  561-671   612-725 (1287)
273 5WBK_A Regulatory-associated p  92.2  0.0059 5.8E-07   72.7   0.0  101  560-671   611-725 (1287)
274 2QK2_A LP04448p; Mini spindles  92.2   0.005 5.8E-07   54.5   0.0  145  548-714    16-163 (242)
275 3W3U_A Importin subunit beta-3  92.2   0.005 5.8E-07   67.5   0.0  115  245-360   397-512 (1078)
276 2IW3_B ELONGATION FACTOR 3A; A  92.0  0.0058 6.5E-07   68.1   0.0  148  548-713   176-324 (986)
277 4G3A_B CLIP-associating protei  91.9  0.0059 6.8E-07   54.0   0.0  150  547-714     7-158 (237)
278 5EWP_B Uncharacterized protein  91.9  0.0062 6.9E-07   55.7   0.0  176  528-716     7-209 (252)
279 4QMI_B Cytoskeleton-associated  91.9   0.006 6.9E-07   54.1   0.0  147  548-715    60-208 (240)
280 4QMJ_A Cytoskeleton-associated  91.9   0.006 6.9E-07   54.1   0.0  147  548-715    60-208 (240)
281 5XAH_A Importin-4; Histone, Ch  91.8  0.0062 7.2E-07   58.5   0.0  153  548-714   235-389 (416)
282 5XAH_C Importin-4; Histone, Ch  91.8  0.0062 7.2E-07   58.5   0.0  153  548-714   235-389 (416)
283 2QK1_A Protein STU2; stu2, Stu  91.8  0.0063 7.3E-07   53.8   0.0  152  548-714    17-176 (249)
284 5H2V_A Importin subunit beta-3  91.8  0.0063 7.4E-07   66.7   0.0  114  246-360   398-512 (1078)
285 6OWT_A AP-2 complex subunit al  91.7  0.0072 7.8E-07   67.7   0.0  142  548-713   442-589 (939)
286 2P8Q_A Importin beta-1 subunit  91.7  0.0066 7.8E-07   64.5   0.0  160  548-715   650-829 (876)
287 5MFO_F YIIIM3AIII; Designed ar  91.6  0.0068   8E-07   51.3   0.0  157  546-715     3-161 (202)
288 5MFO_E YIIIM3AIII; Designed ar  91.6   0.007 8.3E-07   51.2   0.0  157  546-715     3-161 (202)
289 2QNA_A Importin subunit beta-1  91.5  0.0073 8.6E-07   62.8   0.0  159  548-714   525-703 (762)
290 6G4J_B Probable serine/threoni  91.5   0.008 8.8E-07   50.6   0.0  132  548-723    15-146 (148)
291 3W3W_A Importin subunit beta-3  91.3  0.0081 9.5E-07   65.7   0.0   98  609-715   821-920 (1078)
292 3ND2_A Importin subunit beta-1  91.2  0.0083 9.8E-07   63.2   0.0  152  548-713   598-763 (861)
293 5OWU_A Importin subunit beta-1  91.2  0.0083 9.8E-07   63.2   0.0  152  548-713   598-763 (861)
294 5DFZ_B Vacuolar protein sortin  91.0   0.011 1.1E-06   70.6   0.0  159  546-714   463-639 (1460)
295 3W3U_A Importin subunit beta-3  90.7   0.011 1.3E-06   64.7   0.0  157  548-713   440-600 (1078)
296 1QGR_A IMPORTIN BETA SUBUNIT,   90.6   0.011 1.3E-06   62.8   0.0  113  246-360   367-480 (876)
297 4QMH_A LP04448p; PROTEIN BINDI  90.4   0.012 1.4E-06   51.8   0.0  149  548-715    58-209 (241)
298 5A1V_E ADP-RIBOSYLATION FACTOR  90.4   0.013 1.4E-06   64.9   0.0  102  244-359    67-168 (874)
299 5NZR_G Coatomer subunit alpha,  90.4   0.013 1.4E-06   64.9   0.0  102  244-359    67-168 (874)
300 3W3W_A Importin subunit beta-3  90.3   0.013 1.5E-06   64.1   0.0  157  547-714   439-601 (1078)
301 5H2V_A Importin subunit beta-3  90.2   0.013 1.5E-06   64.0   0.0  158  547-714   439-601 (1078)
302 4NEE_G AP-2 complex subunit si  90.1   0.014 1.6E-06   56.7   0.0  141  548-714    77-219 (398)
303 6MQ5_A CLIP-associating protei  90.0   0.015 1.7E-06   52.9   0.0  111  548-670     4-120 (257)
304 4UQI_B AP-2 COMPLEX SUBUNIT AL  90.0   0.015 1.7E-06   60.6   0.0  109  245-359   160-268 (657)
305 4XRI_A Importin Beta; Transpor  89.9   0.014 1.7E-06   61.5   0.0  159  548-715   651-826 (882)
306 4NEE_B AP-2 complex subunit si  89.8   0.016 1.8E-06   56.6   0.0  141  548-714    77-219 (398)
307 6EN4_C Splicing factor 3B subu  89.8   0.015 1.8E-06   61.6   0.0  153  548-714   397-551 (852)
308 5A1V_E ADP-RIBOSYLATION FACTOR  89.6   0.018 1.9E-06   63.8   0.0  141  548-714   397-538 (874)
309 5NZR_G Coatomer subunit alpha,  89.6   0.018 1.9E-06   63.8   0.0  141  548-714   397-538 (874)
310 6OWT_A AP-2 complex subunit al  89.5   0.018   2E-06   64.2   0.0   98  250-360    79-178 (939)
311 5KC2_B Phosphatidylinositol 3-  89.3   0.021 2.1E-06   68.3   0.0  151  548-714   424-610 (1454)
312 2P8Q_A Importin beta-1 subunit  89.3   0.018 2.1E-06   60.9   0.0  154  548-714   367-538 (876)
313 2QNA_A Importin subunit beta-1  89.1   0.019 2.3E-06   59.4   0.0  115  245-360     3-122 (762)
314 1IBR_B RAN  IMPORTIN BETA SUBU  89.1   0.019 2.3E-06   55.6   0.0  154  548-714   129-289 (462)
315 1QGR_A IMPORTIN BETA SUBUNIT,   88.9   0.021 2.4E-06   60.6   0.0  154  548-714   367-538 (876)
316 2DB0_A 253aa long hypothetical  88.9   0.021 2.4E-06   50.5   0.0  141  548-715   108-248 (253)
317 2DB0_B 253aa long hypothetical  88.9   0.021 2.4E-06   50.5   0.0  141  548-715   108-248 (253)
318 4K92_B CLIP-associating protei  88.8   0.022 2.5E-06   52.5   0.0  148  548-714    90-237 (273)
319 6MQ7_B CLIP-associating protei  88.8   0.022 2.5E-06   52.5   0.0  148  548-714    90-237 (273)
320 1GCJ_B IMPORTIN-BETA; HEAT REP  88.7   0.022 2.5E-06   55.4   0.0  154  548-714   135-295 (460)
321 1F59_B IMPORTIN BETA-1/FXFG NU  88.7   0.022 2.6E-06   54.8   0.0  154  548-714   129-289 (442)
322 1UKL_A Importin beta-1 subunit  88.6   0.022 2.6E-06   60.2   0.0  113  246-360   367-480 (876)
323 1U6G_C Cullin homolog 1, RING-  88.2   0.025 2.9E-06   62.9   0.0  146  548-714   891-1036(1230)
324 4MFU_A Beta-catenin-like prote  88.1   0.031 3.1E-06   59.1   0.0  135  246-381    69-222 (490)
325 6CRI_I Bone marrow stromal ant  87.6    0.03 3.5E-06   55.5   0.0  141  548-714    37-177 (570)
326 3QML_D 78 kDa glucose-regulate  87.5   0.038 3.6E-06   55.4   0.0  165  534-712    56-246 (315)
327 5IFE_C Splicing factor 3B subu  87.4   0.036 3.7E-06   65.2   0.0  154  547-714   848-1003(1304)
328 6AHD_1 Pre-mRNA-processing-spl  87.4   0.036 3.7E-06   65.2   0.0  154  547-714   848-1003(1304)
329 5MU7_A Coatomer subunit beta,   87.4   0.031 3.7E-06   52.4   0.0  141  549-716   190-331 (373)
330 5VE8_B Kap123, Histone H3; Bid  87.4   0.031 3.7E-06   61.1   0.0  154  549-714   868-1034(1116)
331 2IX8_A ELONGATION FACTOR 3A; N  87.3   0.034 3.8E-06   61.3   0.0  150  547-713    48-198 (976)
332 3WOY_A CLIP-associating protei  87.3   0.034 3.8E-06   50.1   0.0  147  548-714    78-225 (251)
333 5DN7_A Protein FAM179B; TOG do  87.2   0.035 3.9E-06   52.0   0.0  146  548-714    67-212 (293)
334 4HM9_A Beta-catenin-like prote  87.2    0.04 3.9E-06   59.6   0.0  135  246-381   147-300 (568)
335 6S47_Bi 60S ribosomal protein   87.2   0.035 3.9E-06   61.2   0.0  155  546-713    42-198 (972)
336 6QH5_B AP-2 complex subunit al  87.1   0.034   4E-06   55.8   0.0  142  548-715    50-191 (592)
337 5A1V_G ADP-RIBOSYLATION FACTOR  87.1   0.037   4E-06   61.9   0.0  105  547-670   259-364 (968)
338 3TJZ_B ADP-ribosylation factor  87.0   0.036 4.1E-06   52.5   0.0   16  697-712   225-240 (355)
339 2IW3_B ELONGATION FACTOR 3A; A  86.9   0.037 4.1E-06   61.1   0.0  151  547-714    54-205 (986)
340 5NZR_B Coatomer subunit alpha,  86.8    0.04 4.3E-06   61.6   0.0  105  547-670   259-364 (968)
341 4P6Z_B BST2/tetherin, HIV-1 Vp  86.8   0.037 4.3E-06   55.9   0.0  142  548-715    66-207 (600)
342 5VCH_A Kap123; Bidding yeast k  86.7   0.038 4.4E-06   60.5   0.0  153  550-714   869-1034(1116)
343 6BCU_A mTOR, Target of rapamyc  86.7    0.04 4.4E-06   67.9   0.0  131  549-694   952-1084(2549)
344 6BCX_B mTOR, Target of rapamyc  86.7    0.04 4.4E-06   67.9   0.0  131  549-694   952-1084(2549)
345 5IFE_C Splicing factor 3B subu  86.4   0.045 4.7E-06   64.2   0.0  110  249-359   935-1044(1304)
346 6AHD_1 Pre-mRNA-processing-spl  86.4   0.045 4.7E-06   64.2   0.0  110  249-359   935-1044(1304)
347 6LTJ_L Histone H3.2, Histone H  86.4   0.056 4.7E-06   63.5   0.0  152  563-723  1065-1263(1295)
348 6CRI_R Bone marrow stromal ant  86.2   0.043 4.9E-06   55.5   0.0  139  548-714    63-201 (585)
349 5DFZ_B Vacuolar protein sortin  85.9   0.051 5.3E-06   64.4   0.0  292  245-645   464-781 (1460)
350 2QNA_A Importin subunit beta-1  85.8   0.046 5.4E-06   56.3   0.0  154  548-714     4-164 (762)
351 3WOZ_C CLIP-associating protei  85.7   0.049 5.4E-06   48.6   0.0  154  547-716     5-159 (232)
352 3WOZ_D CLIP-associating protei  85.7   0.049 5.4E-06   48.6   0.0  154  547-716     5-159 (232)
353 5DCQ_C artificial repeat prote  85.5   0.051 5.7E-06   45.4   0.0   47  654-712   120-166 (170)
354 4L7M_A Putative uncharacterize  85.3   0.051   6E-06   48.1   0.0  143  548-713   120-265 (269)
355 4P6Z_B BST2/tetherin, HIV-1 Vp  85.1   0.053 6.2E-06   54.6   0.0  109  245-359   176-284 (600)
356 5MU7_A Coatomer subunit beta,   85.1   0.053 6.2E-06   50.7   0.0  101  598-714   191-292 (373)
357 4UQI_B AP-2 COMPLEX SUBUNIT AL  85.0   0.056 6.3E-06   55.9   0.0  142  548-715    50-191 (657)
358 6MZE_Z Tubulin alpha-1A chain,  84.9   0.055 6.4E-06   53.4   0.0  149  548-715   340-496 (536)
359 4MFU_A Beta-catenin-like prote  84.8   0.067 6.5E-06   56.4   0.0  117  610-733    42-175 (490)
360 5N3U_B Phycocyanobilin lyase s  84.6    0.06 6.9E-06   46.1   0.0  135  547-714    32-167 (208)
361 6QH5_B AP-2 complex subunit al  84.4    0.06   7E-06   53.8   0.0  145  548-713   122-268 (592)
362 2DB0_A 253aa long hypothetical  84.4   0.062 7.1E-06   47.2   0.0  104  547-670    32-136 (253)
363 2DB0_B 253aa long hypothetical  84.4   0.062 7.1E-06   47.2   0.0  104  547-670    32-136 (253)
364 2JKT_A AP-2 COMPLEX SUBUNIT AL  84.2   0.064 7.3E-06   54.8   0.0  140  548-713    75-216 (623)
365 3LTJ_A AlphaRep-4; protein eng  84.1   0.065 7.5E-06   45.7   0.0   28  685-713   140-167 (201)
366 4P6Z_B BST2/tetherin, HIV-1 Vp  84.1   0.065 7.5E-06   54.0   0.0  145  548-713   138-284 (600)
367 6QH7_A AP-2 complex subunit al  84.0   0.067 7.6E-06   54.8   0.0  140  548-713    75-216 (621)
368 6CRI_R Bone marrow stromal ant  83.9   0.067 7.7E-06   53.9   0.0   67  548-625   135-201 (585)
369 4UQI_B AP-2 COMPLEX SUBUNIT AL  83.9   0.069 7.8E-06   55.2   0.0  145  548-713   122-268 (657)
370 5XAH_A Importin-4; Histone, Ch  83.5   0.071 8.2E-06   50.5   0.0  142  561-715   163-307 (416)
371 5XAH_C Importin-4; Histone, Ch  83.5   0.071 8.2E-06   50.5   0.0  142  561-715   163-307 (416)
372 5FRS_A SISTER CHROMATID COHESI  83.5    0.08 8.3E-06   57.5   0.0  149  548-715   282-431 (703)
373 4HM9_A Beta-catenin-like prote  83.5   0.087 8.3E-06   56.8   0.0  136  246-381   198-350 (568)
374 5FRP_A SISTER CHROMATID COHESI  83.4   0.082 8.4E-06   57.5   0.0  149  548-715   282-431 (703)
375 5GM6_G Prp8, Brr2, Snu114, Rse  83.4   0.077 8.4E-06   58.7   0.0   69  248-316   603-671 (971)
376 5ZWM_1 Pre-mRNA-splicing facto  83.4   0.077 8.4E-06   58.7   0.0   69  248-316   603-671 (971)
377 3TJZ_B ADP-ribosylation factor  83.4   0.075 8.5E-06   50.1   0.0  102  596-712   251-352 (355)
378 6CRI_R Bone marrow stromal ant  83.3   0.075 8.6E-06   53.5   0.0  101  246-359   100-200 (585)
379 6U62_A Regulatory-associated p  83.0   0.095   9E-06   62.5   0.0  159  544-715   468-630 (1392)
380 6BCX_W mTOR, Target of rapamyc  82.8   0.098 9.3E-06   62.1   0.0  159  544-715   476-638 (1343)
381 4QMH_A LP04448p; PROTEIN BINDI  82.8   0.081 9.4E-06   46.0   0.0  114  595-716    17-130 (241)
382 6QH5_A AP-2 complex subunit al  82.8   0.083 9.4E-06   54.0   0.0  140  548-713    75-216 (621)
383 6EMK_C Serine/threonine-protei  82.8   0.086 9.4E-06   64.9   0.0   71  548-625   922-993 (2474)
384 5MU7_A Coatomer subunit beta,   82.7   0.082 9.5E-06   49.3   0.0   71  548-624    39-110 (373)
385 6CRI_I Bone marrow stromal ant  82.7   0.081 9.6E-06   52.1   0.0  145  548-713   109-255 (570)
386 4QMI_B Cytoskeleton-associated  82.6   0.084 9.7E-06   46.0   0.0  112  595-715    19-131 (240)
387 4QMJ_A Cytoskeleton-associated  82.6   0.084 9.7E-06   46.0   0.0  112  595-715    19-131 (240)
388 6MZG_E Tubulin alpha-1A chain,  82.5   0.084 9.8E-06   52.4   0.0  147  549-715   315-466 (554)
389 1B3U_A PROTEIN PHOSPHATASE PP2  82.3   0.085   1E-05   51.8   0.0  147  547-713   164-310 (588)
390 2OF3_A ZYG-9; Multifunctional   82.0   0.098 1.1E-05   48.1   0.0  150  548-714    88-237 (266)
391 4I5L_D PP2A A alpha subunit (9  81.8   0.092 1.1E-05   51.5   0.0  147  547-713   160-306 (584)
392 4Y5J_A Mini spindles TOG3; XMA  81.7   0.097 1.1E-05   46.2   0.0   71  548-625    15-89  (248)
393 4P6Z_G BST2/tetherin, HIV-1 Vp  81.6     0.1 1.1E-05   53.7   0.0  137  549-713    81-217 (627)
394 5KC2_B Phosphatidylinositol 3-  81.5    0.11 1.2E-05   61.5   0.0  126  247-379   621-746 (1454)
395 6MZG_E Tubulin alpha-1A chain,  81.1     0.1 1.2E-05   51.7   0.0  151  550-714    57-211 (554)
396 6MZE_Z Tubulin alpha-1A chain,  81.1     0.1 1.2E-05   51.2   0.0  108  600-714   300-412 (536)
397 6RXU_UJ Periodic tryptophan pr  80.9    0.12 1.2E-05   62.5   0.0  152  548-713  1625-1791(1802)
398 5FVM_B SERINE/THREONINE-PROTEI  80.8    0.12 1.3E-05   63.5   0.0  147  548-714  1008-1155(2471)
399 6GWC_C Tubulin alpha chain, Tu  80.7    0.11 1.3E-05   45.3   0.0   49  654-714   120-168 (232)
400 1OYZ_A X-RAY STRUCTURE OF YB61  80.6    0.11 1.3E-05   46.1   0.0   64  549-623    92-156 (280)
401 6GX7_F Tubulin alpha chain, Tu  80.5    0.12 1.3E-05   44.1   0.0  122  548-713    46-167 (201)
402 2NYL_A Protein phosphatase 2,   80.4    0.11 1.3E-05   50.7   0.0  147  547-713   158-304 (582)
403 5VJC_B Protein mini spindles;   80.3    0.12 1.4E-05   47.2   0.0   72  547-625    50-121 (271)
404 6RXV_UJ Periodic tryptophan pr  80.3    0.13 1.4E-05   62.1   0.0  152  548-713  1625-1791(1802)
405 4I5L_D PP2A A alpha subunit (9  80.2    0.11 1.4E-05   50.8   0.0  109  547-670   238-349 (584)
406 1IBR_B RAN  IMPORTIN BETA SUBU  80.2    0.12 1.4E-05   49.6   0.0  156  549-716   261-440 (462)
407 1B3U_A PROTEIN PHOSPHATASE PP2  80.1    0.12 1.4E-05   50.8   0.0  109  547-670   242-353 (588)
408 4P6Z_G BST2/tetherin, HIV-1 Vp  80.0    0.13 1.4E-05   52.9   0.0   67  548-625   152-218 (627)
409 5NR4_A CLIP-associating protei  80.0    0.12 1.4E-05   44.1   0.0  109  244-360    51-159 (230)
410 2P8Q_A Importin beta-1 subunit  79.9    0.12 1.4E-05   54.0   0.0  154  548-714   129-289 (876)
411 4I5L_D PP2A A alpha subunit (9  79.9    0.12 1.4E-05   50.6   0.0  147  547-713   320-466 (584)
412 1QGR_A IMPORTIN BETA SUBUNIT,   79.8    0.12 1.4E-05   54.2   0.0  154  548-714   129-289 (876)
413 1B3U_A PROTEIN PHOSPHATASE PP2  79.8    0.12 1.5E-05   50.6   0.0  146  547-712   324-469 (588)
414 6MZE_Z Tubulin alpha-1A chain,  79.7    0.13 1.5E-05   50.5   0.0  152  550-715    57-212 (536)
415 5F0N_A cohesin subunit Pds5, K  79.1    0.17 1.6E-05   59.2   0.0  150  547-714   271-420 (1175)
416 4NEE_G AP-2 complex subunit si  78.8    0.15 1.7E-05   48.9   0.0  115  548-671   149-273 (398)
417 3W3U_A Importin subunit beta-3  78.8    0.14 1.7E-05   55.2   0.0  158  548-714   849-1007(1078)
418 4NEE_B AP-2 complex subunit si  78.7    0.15 1.7E-05   49.0   0.0  115  548-671   149-273 (398)
419 3DAD_A FH1/FH2 domain-containi  78.5    0.18 1.7E-05   50.5   0.0  154  565-729   135-309 (339)
420 5VJC_A Protein mini spindles;   78.4    0.16 1.7E-05   46.5   0.0   73  546-625    49-121 (271)
421 5WBJ_A Regulatory-associated p  78.3    0.18 1.8E-05   59.3   0.0  156  548-716   467-631 (1287)
422 5WBK_A Regulatory-associated p  78.3    0.18 1.8E-05   59.3   0.0  156  548-716   467-631 (1287)
423 6EN4_C Splicing factor 3B subu  78.2    0.15 1.8E-05   53.3   0.0  154  548-715   192-347 (852)
424 5F0O_A cohesin subunit Pds5, K  78.2    0.18 1.8E-05   58.5   0.0  150  547-714   280-429 (1133)
425 2NYL_A Protein phosphatase 2,   77.8    0.16 1.9E-05   49.5   0.0  109  547-670   236-347 (582)
426 3W3W_A Importin subunit beta-3  77.6    0.16 1.9E-05   54.7   0.0  157  548-714   849-1007(1078)
427 4LAC_A Serine/threonine-protei  77.5    0.17 1.9E-05   44.2   0.0  115  239-360    27-141 (258)
428 6FT5_A A3_A3; alphaRep, artifi  77.5    0.17 1.9E-05   47.7   0.0   60  547-623    54-113 (409)
429 1F59_B IMPORTIN BETA-1/FXFG NU  77.4    0.17   2E-05   48.1   0.0  158  547-714    35-204 (442)
430 2NYL_A Protein phosphatase 2,   77.3    0.16   2E-05   49.4   0.0   70  547-625   318-387 (582)
431 5FVM_B SERINE/THREONINE-PROTEI  77.2    0.18   2E-05   61.6   0.0   71  548-625   925-996 (2471)
432 3LTJ_A AlphaRep-4; protein eng  77.2    0.18   2E-05   42.7   0.0  121  548-712    77-197 (201)
433 5JO8_A CEP104; centriolar prot  77.2    0.18   2E-05   46.5   0.0  155  548-714    87-245 (279)
434 4P6Z_G BST2/tetherin, HIV-1 Vp  77.2    0.18   2E-05   51.7   0.0  101  246-359   117-217 (627)
435 1GCJ_B IMPORTIN-BETA; HEAT REP  77.2    0.17   2E-05   48.4   0.0  154  549-714   267-444 (460)
436 6GWC_C Tubulin alpha chain, Tu  76.9    0.18 2.1E-05   43.9   0.0  121  548-712   108-228 (232)
437 3QML_D 78 kDa glucose-regulate  76.8    0.22 2.1E-05   49.4   0.0  104  609-717    42-154 (315)
438 4G3A_B CLIP-associating protei  76.8    0.18 2.1E-05   43.5   0.0  113  244-358     6-118 (237)
439 6IDX_A Engulfment and cell mot  76.8    0.22 2.1E-05   52.8   0.0  157  563-731   102-272 (524)
440 6IE1_A Engulfment and cell mot  76.8    0.22 2.1E-05   52.8   0.0  157  563-731   102-272 (524)
441 5H2V_A Importin subunit beta-3  76.6    0.18 2.1E-05   54.2   0.0  157  548-714   849-1007(1078)
442 1TE4_A conserved protein MTH18  76.5    0.19 2.2E-05   39.5   0.0  118  548-710    13-130 (131)
443 6S47_Bi 60S ribosomal protein   76.5     0.2 2.2E-05   54.8   0.0  155  548-714   127-321 (972)
444 1OYZ_A X-RAY STRUCTURE OF YB61  76.4    0.19 2.2E-05   44.5   0.0   96  596-712    91-187 (280)
445 5NR4_A CLIP-associating protei  76.2    0.19 2.2E-05   42.7   0.0  111  595-713     6-122 (230)
446 5A1V_E ADP-RIBOSYLATION FACTOR  75.9    0.22 2.3E-05   54.5   0.0  137  548-713    69-205 (874)
447 5NZR_G Coatomer subunit alpha,  75.9    0.22 2.3E-05   54.5   0.0  137  548-713    69-205 (874)
448 6HWP_A A3_bGFPD; alphaRep, art  75.5    0.21 2.4E-05   46.8   0.0   49  654-714   129-177 (409)
449 3W3U_A Importin subunit beta-3  75.5    0.21 2.4E-05   53.8   0.0  152  549-714   358-512 (1078)
450 4QMI_B Cytoskeleton-associated  75.5    0.21 2.4E-05   43.2   0.0  107  245-360    59-167 (240)
451 4QMJ_A Cytoskeleton-associated  75.5    0.21 2.4E-05   43.2   0.0  107  245-360    59-167 (240)
452 2IX8_A ELONGATION FACTOR 3A; N  75.4    0.22 2.4E-05   54.3   0.0  153  548-713   128-318 (976)
453 5XAH_A Importin-4; Histone, Ch  75.4    0.21 2.4E-05   46.9   0.0  162  548-713    33-222 (416)
454 5XAH_C Importin-4; Histone, Ch  75.4    0.21 2.4E-05   46.9   0.0  162  548-713    33-222 (416)
455 5H2V_A Importin subunit beta-3  75.1    0.22 2.5E-05   53.6   0.0  154  548-714   357-512 (1078)
456 6OWT_A AP-2 complex subunit al  75.0    0.24 2.6E-05   54.6   0.0  140  548-713    75-216 (939)
457 4G3A_B CLIP-associating protei  74.9    0.22 2.6E-05   42.9   0.0  107  548-671    91-198 (237)
458 4XL5_C Green fluorescent prote  74.6    0.23 2.7E-05   43.8   0.0  121  548-712   139-259 (263)
459 4FDD_A Transportin-1, RNA-bind  74.5    0.23 2.7E-05   51.3   0.0  155  548-714   129-286 (852)
460 4D4Z_A DEOXYHYPUSINE HYDROXYLA  74.4    0.23 2.7E-05   44.2   0.0  124  546-711     9-134 (294)
461 4D50_A DEOXYHYPUSINE HYDROXYLA  74.4    0.23 2.7E-05   44.2   0.0  124  546-711     9-134 (294)
462 6QH5_A AP-2 complex subunit al  74.2    0.24 2.8E-05   50.3   0.0   69  548-625   147-217 (621)
463 5LPH_B Centrosomal protein of   74.0    0.26 2.8E-05   45.9   0.0  155  549-714    94-251 (288)
464 1QBK_B STRUCTURE OF THE KARYOP  73.9    0.24 2.8E-05   51.6   0.0  156  548-715   129-287 (890)
465 3W3W_A Importin subunit beta-3  73.9    0.24 2.9E-05   53.2   0.0  153  548-714   357-512 (1078)
466 1IBR_B RAN  IMPORTIN BETA SUBU  73.6    0.25 2.9E-05   47.1   0.0  158  547-714    35-204 (462)
467 5VCH_A Kap123; Bidding yeast k  73.4    0.26   3E-05   53.4   0.0  153  548-714   361-516 (1116)
468 6QH7_A AP-2 complex subunit al  73.4    0.26   3E-05   50.0   0.0   69  548-625   147-217 (621)
469 2JKT_A AP-2 COMPLEX SUBUNIT AL  73.3    0.27   3E-05   49.9   0.0   69  548-625   147-217 (623)
470 1GCJ_B IMPORTIN-BETA; HEAT REP  73.0    0.27 3.1E-05   47.0   0.0  158  547-714    41-210 (460)
471 1OYZ_A X-RAY STRUCTURE OF YB61  73.0    0.27 3.1E-05   43.4   0.0  121  547-710   159-279 (280)
472 2JKT_A AP-2 COMPLEX SUBUNIT AL  72.8    0.28 3.2E-05   49.7   0.0   67  548-623   330-397 (623)
473 5VE8_B Kap123, Histone H3; Bid  72.7    0.27 3.2E-05   53.1   0.0  153  548-714   361-516 (1116)
474 4ZV6_A AlphaRep-7, Octarellin   71.7     0.3 3.5E-05   43.7   0.0   29  685-714   140-168 (294)
475 6BZX_A alpha-Rep, Octarellin V  71.4    0.31 3.6E-05   43.6   0.0   29  685-714   140-168 (294)
476 5IFE_C Splicing factor 3B subu  70.4    0.38 3.9E-05   55.8   0.0  154  548-715   644-799 (1304)
477 6AHD_1 Pre-mRNA-processing-spl  70.4    0.38 3.9E-05   55.8   0.0  154  548-715   644-799 (1304)
478 2QK2_A LP04448p; Mini spindles  70.3    0.34   4E-05   41.6   0.0  113  243-358    13-126 (242)
479 6MZG_E Tubulin alpha-1A chain,  70.0    0.35 4.1E-05   47.5   0.0   71  549-625   138-211 (554)
480 6QH7_A AP-2 complex subunit al  69.9    0.36 4.1E-05   48.9   0.0  100  247-359    76-177 (621)
481 1UKL_A Importin beta-1 subunit  69.9    0.35 4.1E-05   50.3   0.0  154  548-714   129-289 (876)
482 6EMK_C Serine/threonine-protei  69.9    0.38 4.1E-05   58.8   0.0  136  562-714  1016-1152(2474)
483 4XL5_C Green fluorescent prote  69.9    0.36 4.1E-05   42.4   0.0   49  654-714   120-168 (263)
484 4D4Z_A DEOXYHYPUSINE HYDROXYLA  69.8    0.36 4.1E-05   42.9   0.0  127  547-715   161-289 (294)
485 4D50_A DEOXYHYPUSINE HYDROXYLA  69.8    0.36 4.1E-05   42.9   0.0  127  547-715   161-289 (294)
486 6QH5_A AP-2 complex subunit al  69.7    0.37 4.2E-05   48.8   0.0   67  548-623   330-397 (621)
487 4XL5_C Green fluorescent prote  69.5    0.37 4.2E-05   42.3   0.0   88  600-714   143-230 (263)
488 6LTJ_L Histone H3.2, Histone H  69.2    0.52 4.4E-05   55.1   0.0  106  609-716  1064-1189(1295)
489 5WLC_LM rpS18_uS13, rpS4_eS4,   69.1    0.44 4.4E-05   57.4   0.0  153  548-713  1597-1758(1769)
490 5YVI_A Transportin-1, RNA-bind  69.1    0.37 4.4E-05   49.7   0.0  155  548-714   131-288 (868)
491 3VWA_A Cytoplasmic export prot  68.9    0.42 4.5E-05   49.3   0.0  111  594-715   340-450 (560)
492 3VWA_B Cytoplasmic export prot  68.9    0.42 4.5E-05   49.2   0.0  111  594-715   340-450 (560)
493 3C5W_A PP2A A subunit, PP2A C;  68.8    0.38 4.5E-05   40.3   0.0  109  245-360     7-115 (232)
494 4K92_B CLIP-associating protei  68.6    0.41 4.6E-05   43.1   0.0  109  244-360   129-237 (273)
495 6MQ7_B CLIP-associating protei  68.6    0.41 4.6E-05   43.1   0.0  109  244-360   129-237 (273)
496 4LAC_A Serine/threonine-protei  68.3    0.41 4.7E-05   41.4   0.0  109  245-360   111-219 (258)
497 6MQ5_A CLIP-associating protei  68.0    0.43 4.8E-05   42.3   0.0  108  245-360    49-157 (257)
498 2QK1_A Protein STU2; stu2, Stu  67.9    0.42 4.9E-05   40.9   0.0  116  244-360   103-221 (249)
499 4D4Z_A DEOXYHYPUSINE HYDROXYLA  67.6    0.43   5E-05   42.3   0.0   60  547-623    74-135 (294)
500 4D50_A DEOXYHYPUSINE HYDROXYLA  67.6    0.43   5E-05   42.3   0.0   60  547-623    74-135 (294)

No 1
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=99.69  E-value=6.3e-22  Score=206.93  Aligned_cols=453  Identities=100%  Similarity=1.422  Sum_probs=304.9  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      .++.+..++.+.++.++..++.+|..++...+.....+...++++.+..++.+.+..++..++.++.+++.........+
T Consensus         3 ~l~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~   82 (457)
T 1XM9_A            3 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET   82 (457)
T ss_dssp             CHHHHHHHHHSSCTHHHHHHHHHHHHHTSSCSSHHHHHHHTTHHHHHHHHTTSSCHHHHHHHHHHHHHHHSSCHHHHHHH
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHhhCCHHHHHHH
Confidence            45566777777778889999999999885444444445555778888888888788899999999999886544333444


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFN  405 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~  405 (747)
                      ...+.++.++.++....+..++..++.+|.+++........+..++++.|+.++..+.++|+.+.+.+.....++++...
T Consensus        83 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~  162 (457)
T 1XM9_A           83 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFN  162 (457)
T ss_dssp             HHTTCHHHHHHHHTTCCCHHHHHHHHHHHHHHHTSSSTHHHHHHHHHHHCCCCCCHHHHTCC---------CCCHHHHHH
T ss_pred             HhcChHHHHHHHhhhCCCHHHHHHHHHHHHHHhCCHHHHHHHHcchHHHHHHHhccccCCCCCCCCCcccccCCHHHHHH
Confidence            44567777777775344677888899999999875444333335788999999999999999988887777777777766


Q NP_000290.2     406 ATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYR  485 (747)
Q Consensus       406 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  485 (747)
                      +..+|..                     +...+..++.+....|+++.|+.+++.+......+..-.+.+..+|.|++..
T Consensus       163 a~~~L~~---------------------l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~l~~l~~~  221 (457)
T 1XM9_A          163 ATGCLRN---------------------LSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYR  221 (457)
T ss_dssp             HHHHHHH---------------------HTTSHHHHHHHTTSTTHHHHHHHHHHHHHHHTCTTCTTHHHHHHHHHHHTTT
T ss_pred             HHHHHHH---------------------HccChHHHHHHHhcccHHHHHHHHHHHhhhcCcCCHHHHHHHHHHHHHHhcc
Confidence            6665543                     2222223444555567788888887765555556777888999999999999


Q NP_000290.2     486 LDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATL  565 (747)
Q Consensus       486 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr  565 (747)
                      .+.+.+..+..+++.++..+..+...+|+.+...+++....+|.++....+......+.+.++++.++.++....+..++
T Consensus       222 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~  301 (457)
T 1XM9_A          222 LDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATL  301 (457)
T ss_dssp             HHHHSCCHHHHHHHTC----------------------------CCCCCSSCCGGGGGGSHHHHHHHHHHHHHCCCHHHH
T ss_pred             cccCCCcchhhhhhcccccccccccccccCcccchhccccccCCCCcccCCCchhHHhhchhHHHHHHHHhccCCCHHHH
Confidence            99999999999999999999999999999999999999999999998888888888888999999999999733556777


Q NP_000290.2     566 EACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLT  645 (747)
Q Consensus       566 ~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~  645 (747)
                      ..++.+|.+++..............+...++++.|+.++.+.++.++..++.+|.+++..+.....+..++++.++.++.
T Consensus       302 ~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~l~~~l~  381 (457)
T 1XM9_A          302 EACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLT  381 (457)
T ss_dssp             HHHHHHHHHHTTCSSSHHHHHHHCCCCCSCCHHHHHHHTTCSCHHHHHHHHHHHHHHHTSGGGHHHHHHHTHHHHHHTTT
T ss_pred             HHHHHHHHHHHhccccccCCcchhhhhhcchHHHHHHHHhcCCHHHHHHHHHHHHHHhcCHHHHHHHHcccHHHHHHHHh
Confidence            78999999998753200000002233456788999999988888999999999999996644432233347777777776


Q NP_000290.2     646 SHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG  719 (747)
Q Consensus       646 s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~~~  719 (747)
                      ........++.++..++.+|.+|+...+.....+.+.++++.|..++....++.++..++.+|.+++.+.+.+.
T Consensus       382 ~~~~~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~ll~~~~~~~v~~~a~~~L~~l~~~~~~~~  455 (457)
T 1XM9_A          382 SHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQG  455 (457)
T ss_dssp             SCCSCSTTHHHHHHHHHHHHHHHHTTCTHHHHHHCCHHHHHHHHHHHHCTTCHHHHHHHHHHHHTTSSSTTCSS
T ss_pred             cCCCCCCCCHHHHHHHHHHHHHHHhcCHHHHHHHHhccHHHHHHHHHhCCCCHHHHHHHHHHHHHHhhcHhHhc
Confidence            52000000567888999999999865566666777778889999988862278899999999999998877654


No 2
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=99.41  E-value=1.1e-17  Score=185.51  Aligned_cols=438  Identities=32%  Similarity=0.540  Sum_probs=299.3  Template_Neff=11.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~  323 (747)
                      ..++.++.++...++.++..++.+|.+++.........+...++++.|+.++.+.+..++..++.+|.+++.. ......
T Consensus        48 ~~l~~li~~L~~~~~~v~~~a~~~L~~L~~~~~~~~~~~~~~g~i~~Lv~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~  127 (584)
T 3L6X_A           48 PELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKI  127 (584)
T ss_dssp             CCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHGGGCSSHHHHHHHHHHHHHHTSSSCHHHHH
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCCcHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCCHHHHH
Confidence            4566677777777788899999999998854444444455567888888888887788999999999999864 333444


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMS--REVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~--~~~~~~~  401 (747)
                      .+...+.++.++.++....+..++..++.+|.+++........++..++..|+.++..+.++|........  ....+++
T Consensus       128 ~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~L~~~~~~~~~l~~~~l~~L~~~l~~~~~~~~~~~~~~~~~~~~~~~~  207 (584)
T 3L6X_A          128 AIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPNEDCKPRHIEWES  207 (584)
T ss_dssp             HHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHTTSGGGHHHHHHHTHHHCCCCCCHHHHCCC----------CCCCHH
T ss_pred             HHHcCChHHHHHHHHHHcCCHHHHHHHHHHHHHHhcCHHHHHHHHHHHHHHHHHhccccCCCCCCCCCcCCCCcccChHH
Confidence            44555778888888863346678889999999998765544444445778888888888877754332211  1223455


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD-AGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      +..++.++|+.                     ++..+ ..++.++...|+++.|+..++.++....-+.+.+++|.++|.
T Consensus       208 v~~~a~~~L~~---------------------l~~~~~~~~~~l~~~~g~v~~L~~~l~~~~~~~~~~~~~~~~a~~~L~  266 (584)
T 3L6X_A          208 VLTNTAGCLRN---------------------VSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR  266 (584)
T ss_dssp             HHHHHHHHHHH---------------------HTSSCHHHHHHHHHSTTHHHHHHHHHHHHHHTTCCSCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHH---------------------HhcCCHHHHHHHHhCCCHHHHHHHHHHHHhcCCCCChHHHHHHHHHHH
Confidence            66666665543                     22222 245556666789999999888765544557788999999999


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ||++..+.++|...+..+....           ..+              +-...+......+.+.++++.|+.++....
T Consensus       267 ~L~~~~~~~~~~~~~~~~~~~~-----------~~~--------------~~~~~~~~~~~~l~~~~~~~~l~~ll~~~~  321 (584)
T 3L6X_A          267 NLSYQVHREIPQAERYQEAAPN-----------VAN--------------NTGTSPARGYELLFQPEVVRIYISLLKESK  321 (584)
T ss_dssp             HHHTTHHHHSTTCCC---------------------------------------CCCCGGGGGGSHHHHHHHHHHHHHCC
T ss_pred             HHHhhhhccChhHHHHHHhcCc-----------CCC--------------CCCCCChhhhhHhhChhHHHHHHHHHHcCC
Confidence            9999998888765554432110           000              111222233344567889999999998423


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEV  640 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~L  640 (747)
                      ++.++..++.+|.+++......... ....+.+.++++.|+.++.+.++.++..++++|.+|+........+..++++.|
T Consensus       322 ~~~~~~~a~~~L~~L~~~~~~~~~~-~~~~~~~~~~l~~L~~ll~~~~~~v~~~a~~~L~~L~~~~~~~~~l~~~~l~~L  400 (584)
T 3L6X_A          322 TPAILEASAGAIQNLCAGRWTYGRY-IRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNL  400 (584)
T ss_dssp             CHHHHHHHHHHHHHHHSSCSHHHHH-HHHHHTSHHHHHHHHHGGGCSCHHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHhCCCccCCHH-HHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcChHHHHHHHcchHHHH
Confidence            7788899999999998742100000 233445678899999999988889999999999999877444333334677888


Q NP_000290.2     641 TRLLTSHTGNT--SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS-ASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       641 l~LL~s~s~~~--~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      +.++.......  ..+..++..++.+|.+++...+.....+.+.++++.|+.++... .+..++..|+.+|.+++...+.
T Consensus       401 ~~~L~~~~~~~~~~~~~~~~~~~l~~L~~l~~~~~~~~~~l~~~~~l~~L~~ll~~~~~~~~v~~~a~~~L~~l~~~~~~  480 (584)
T 3L6X_A          401 VKNLPGGQQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKEL  480 (584)
T ss_dssp             HHTSSSSSCSGGGTCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHTCSSSCHHHHHHHHHHHHHHHTSHHH
T ss_pred             HHcCCCCCCCCCcCCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCHHH
Confidence            88776521000  00344577889999998876666777777888899999988653 1478899999999999999999


Q NP_000290.2     718 QGVLRQQGFDRN  729 (747)
Q Consensus       718 ~~~~~~~~~~~~  729 (747)
                      ...+.+.|+-..
T Consensus       481 ~~~l~~~g~~~~  492 (584)
T 3L6X_A          481 RKPLEKEGWKKS  492 (584)
T ss_dssp             HHHHHTTTCCGG
T ss_pred             HHHHHHcCCchh
Confidence            999998888766


No 3
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=98.56  E-value=1.1e-11  Score=126.19  Aligned_cols=369  Identities=14%  Similarity=0.172  Sum_probs=230.1  Template_Neff=13.100

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      ....++.+...+.+.++.++..++.++..+....... ...+...++++.++..+. ..++.++..++.++..++.....
T Consensus        11 ~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   90 (466)
T 5D5K_C           11 VNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSE   90 (466)
T ss_dssp             CSCCHHHHHHHHTSSCHHHHHHHHHHHHHHHTCSSCCCHHHHHHTTHHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHH
T ss_pred             cCcCHHHHHHHHccCCHHHHHHHHHHHHHHHhcCCCCCHHHHHHcCcHHHHHHHhhCCCChHHHHHHHHHHHHHcCCChH
Confidence            4456667777777778888999999998887643221 122333456777777776 34567888899999888764443


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++..+.           .+..
T Consensus        91 ~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~-----------~~~~  158 (466)
T 5D5K_C           91 QTKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPD-----------LSTL  158 (466)
T ss_dssp             HHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHTTCSSC-----------GGGS
T ss_pred             HHHHHhccchHHHHHHHhc-CCCCcHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhCCC-----------cccc
Confidence            3333444457777888876 56778888999999998875432 222333 67777777776421           1112


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..++..-.                     .............+++..+...++.      -+..-...+...
T Consensus       159 ~~~~~~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  211 (466)
T 5D5K_C          159 ACGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWA  211 (466)
T ss_dssp             CHHHHHHHHHHHHHHS---------------------CCCSSCCCHHHHHHHHHHHHHHTTS------SCHHHHHHHHHH
T ss_pred             cHHHHHHHHHHHHHHH---------------------cCCCCCCChHHHHHHHHHHHHHHcC------CCHHHHHHHHHH
Confidence            3334444433332211                     1011111111123444444443321      112222223333


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       212 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  240 (466)
T 5D5K_C          212 ISYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-  240 (466)
T ss_dssp             HHHHTSSC--------------------------------------------------HHHHHHHHTTTCHHHHHHHHT-
T ss_pred             HHHHhcCC--------------------------------------------------chHHHHHHHCChHHHHHHHhc-
Confidence            33332110                                                  001111234567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++
T Consensus       241 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~  315 (466)
T 5D5K_C          241 ATELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGL  315 (466)
T ss_dssp             CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTC
T ss_pred             CCCchHHHHHHHHHHHHhcCCHH-----HHHHHHccChhHhHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCH
Confidence            46778888999999999875332     233334567888999999888889999999999999876 322 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++.+..++.+      .++.++..++.+|.+++.. .......+.+.++++.+..++.+. ++.++..++.+|.+++.
T Consensus       316 ~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~  386 (466)
T 5D5K_C          316 VPFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  386 (466)
T ss_dssp             HHHHHHHHHS------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHHGGGCS-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHH
Confidence            8888888876      3678889999999999874 233344455556788888888866 78899999999999987


No 4
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=98.55  E-value=1.3e-11  Score=128.97  Aligned_cols=381  Identities=18%  Similarity=0.200  Sum_probs=233.7  Template_Neff=12.000

Q NP_000290.2     238 EDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQN------------VQQ  305 (747)
Q Consensus       238 ~~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~e------------Vr~  305 (747)
                      .+..+...+++.++.++...+...   ++.+|..++.. ......+...+.++.+..++...+..            ++.
T Consensus        25 ~~~~~~~~~i~~l~~~l~~~~~~~---a~~~L~~l~~~-~~~~~~~~~~g~i~~L~~ll~~~~~~~~~~~~~~~~~~v~~  100 (458)
T 3NMZ_A           25 SHLGTKVEMVYSLLSMLGTHDKDD---MSRTLLAMSSS-QDSCISMRQSGCLPLLIQLLHGNDKDSVLLGNSRGSKEARA  100 (458)
T ss_pred             HHhHhccchHHHHHHHhCCCCHHH---HHHHHHHHhCC-chHHHHHHHcCcHHHHHHHhcCCChhhcCCCCcccCHHHHH
Confidence            344445556677777776554443   77778777643 23333444556778888888765555            888


Q NP_000290.2     306 AAAGALRNLVFRST---TNKLETRRQNGIREAVSLLR--------------------RTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       306 ~AL~aLs~La~~~~---~~~~~ll~~~IL~~Ll~lL~--------------------ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      .++.+|.+++...+   .....+...+.++.+...+.                    ...+..++..++.++.+++....
T Consensus       101 ~a~~~L~~l~~~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~L~~l~~~~~  180 (458)
T 3NMZ_A          101 RASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEE  180 (458)
T ss_pred             HHHHHHHHHHcCCCCCHHHHHHHHHCCcHHHHHHHHHhhhhcccchhhHHHHHHhcCCCChHHHHHHHHHHHHHHcCChH
Confidence            99999999885432   22222222334444444421                    01234455667778887776554


Q NP_000290.2     363 LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAG  440 (747)
Q Consensus       363 ~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~  440 (747)
                      ....+.. ++++.|+.++.......    .... ...++++...+..+|..                     +... +..
T Consensus       181 ~~~~~~~~~~~~~l~~~l~~~~~~~----~~~~-~~~~~~~~~~a~~~L~~---------------------l~~~~~~~  234 (458)
T 3NMZ_A          181 HRHAMNELGGLQAIAELLQVDCEMY----GLTN-DHYSITLRRYAGMALTN---------------------LTFGDVAN  234 (458)
T ss_pred             HHHHHHHCChHHHHHHHHhccccCC----CCCC-CCCCHHHHHHHHHHHHH---------------------HHcCCHHH
Confidence            4444444 77888888877532211    1110 11244554444444432                     1111 111


Q NP_000290.2     441 RQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDK  520 (747)
Q Consensus       441 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  520 (747)
                      ++.+....|+++.|...++.      .+..-.+.+..+|.|++..-+.                                
T Consensus       235 ~~~~~~~~~~i~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~--------------------------------  276 (458)
T 3NMZ_A          235 KATLCSMKGCMRALVAQLKS------ESEDLQQVIASVLRNLSWRADV--------------------------------  276 (458)
T ss_pred             HHHHHHhCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHCCCCh--------------------------------
Confidence            22233445667777666542      2334445555566665431100                                


Q NP_000290.2     521 MMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQ  599 (747)
Q Consensus       521 ~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~  599 (747)
                                       .....+.+.++++.|+.++....+..++..++++|.+++...+.     ....+.. .++++.
T Consensus       277 -----------------~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~  334 (458)
T 3NMZ_A          277 -----------------NSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAF  334 (458)
T ss_pred             -----------------hHHHHHHHCCHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCch-----hHHHHHHhcChHHH
Confidence                             01122356678888888887325667888999999999874332     2233344 778888


Q NP_000290.2     600 IARLLQS----GNSDVVRSGASLLSNMSR---H-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       600 Ll~LL~s----~d~eVr~~AL~aLsnLa~---~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      |+.++..    .+..++..++.+|.+++.   . ... ..+...++++.|+.++..      .++.++..++++|.+++.
T Consensus       335 l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~~  408 (458)
T 3NMZ_A          335 LVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSA  408 (458)
T ss_pred             HHHHHcCCCCCCCHHHHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhCC------CCHHHHHHHHHHHHHHHC
Confidence            8888872    346778889999988863   2 222 233456788888888876      367889999999999998


Q NP_000290.2     671 SQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       671 ~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ..+.....+.+.++++.|..++.+. ++.++..++.+|.+++...
T Consensus       409 ~~~~~~~~l~~~~~~~~L~~ll~~~-~~~v~~~a~~~L~~l~~~~  452 (458)
T 3NMZ_A          409 RNPKDQEALWDMGAVSMLKNLIHSK-HKMIAMGSAAALRNLMANR  452 (458)
T ss_pred             CCHHHHHHHHHCCcHHHHHHHHhCC-CHHHHHHHHHHHHHHHcCC
Confidence            5566677777778899999988876 6778999999999998654


No 5
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=98.54  E-value=1.3e-11  Score=125.71  Aligned_cols=369  Identities=14%  Similarity=0.172  Sum_probs=229.2  Template_Neff=13.100

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      ....++.+...+.+.++.++..++.++..+....... ...+...++++.++..+. ..++.++..++.++..++.....
T Consensus        11 ~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   90 (466)
T 4UAF_B           11 VNWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSE   90 (466)
T ss_pred             cCcCHHHHHHHHccCCHHHHHHHHHHHHHHHhcCCCCCHHHHHHcCcHHHHHHHhhCCCChHHHHHHHHHHHHHhcCChH
Confidence            4456667777777778888999999998887643221 122333456777777776 34567888899999888764443


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++..+.           .+..
T Consensus        91 ~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~-----------~~~~  158 (466)
T 4UAF_B           91 QTKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPD-----------LSTL  158 (466)
T ss_pred             HHHHHHccChHHHHHHHhc-CCCCCHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhCCC-----------cccc
Confidence            3333444457777888876 56778888999999998875432 222233 67777777775421           1112


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..++..-.                     .............+++..+...+..      -+..-...+...
T Consensus       159 ~~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  211 (466)
T 4UAF_B          159 ACGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWA  211 (466)
T ss_pred             cHHHHHHHHHHHHHHH---------------------cCCCCCCChhHHHHHHHHHHHHHcC------CCHHHHHHHHHH
Confidence            3334333333332211                     0001111111113344444433321      111222222333


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       212 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  240 (466)
T 4UAF_B          212 ISYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-  240 (466)
T ss_pred             HHHHhcCC--------------------------------------------------cHHHHHHHHCChHHHHHHHhc-
Confidence            33332110                                                  001112245567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++
T Consensus       241 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~  315 (466)
T 4UAF_B          241 ATELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGL  315 (466)
T ss_pred             CCChhHHHHHHHHHHHHhcCCHH-----HHHHHhccCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCH
Confidence            46778888999999999875332     233334567888899999888889999999999999876 322 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++.+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++.
T Consensus       316 ~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~  386 (466)
T 4UAF_B          316 VPFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  386 (466)
T ss_pred             HHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHH
Confidence            8888888876      3678889999999999874 233344455556788888888876 78899999999999987


No 6
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=98.52  E-value=1.7e-11  Score=122.96  Aligned_cols=360  Identities=16%  Similarity=0.184  Sum_probs=217.1  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+. ..++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        49 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  128 (426)
T 4U5L_A           49 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  128 (426)
T ss_dssp             CHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHHTCHHHHHH
T ss_pred             cHHHHHHHhccCCChHHHHHHHHHHHHHhCCCHHHHHHHHhcCcHHHHHHHhcCCChHHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665 445678888899998887654433334444567778888888778888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       129 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  191 (426)
T 4U5L_A          129 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  191 (426)
T ss_dssp             HHHTTCHHHHHHTTC-SSCGGGSCHHHHHHHHHHHHHHTCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHhh-CCCCchhhHHHHHHHHHHHHHHHcCCCCCCCccHHHHHHHHHHHHHhC----------------
Confidence            334456677777765 32222     67778888888776433222221  2555666665542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..++..-....      +              .....+. -.+++..|...+..      .+..-...+..
T Consensus       192 ~~~~~~~~a~~~l~~l~~~~------~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~  244 (426)
T 4U5L_A          192 NDPEVLADSCWAISYLTDGP------N--------------ERIEMVV-KKGVVPQLVKLLGA------TELPIVTPALR  244 (426)
T ss_dssp             SCHHHHHHHHHHHHHHTSSC------H--------------HHHHHHH-TTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhhCC------c--------------HHHHHHh-hcChHHHHHHHhcC------CCccHHHHHHH
Confidence            13444444444443211100      0              0000000 12233333333221      11122222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++...-                                                  ......+.+.++++.+..++.
T Consensus       245 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  274 (426)
T 4U5L_A          245 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  274 (426)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHhccchHHHHHHHhc
Confidence            333332100                                                  001112245567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       275 -~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~  348 (426)
T 4U5L_A          275 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  348 (426)
T ss_dssp             -CSSHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHT
T ss_pred             -CCChHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899998888888999999999999875 2 22 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.++
T Consensus       349 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~ll~~~-~~~v~~~a~~~l  421 (426)
T 4U5L_A          349 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  421 (426)
T ss_dssp             TCHHHHHHGGGS------CCHHHHHHHHHHHHHHHHHHHTTTCHHHHHHHHHHTTHHHHHHGGGGSS-CHHHHHHHHHHH
T ss_pred             CcHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHHHHhcCchHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            678888888876      3678899999999999763      123333444556788888888776 788898888888


Q NP_000290.2     709 SDMW  712 (747)
Q Consensus       709 snL~  712 (747)
                      .++.
T Consensus       422 ~~~~  425 (426)
T 4U5L_A          422 EKYF  425 (426)
T ss_dssp             HHHC
T ss_pred             HHHc
Confidence            7764


No 7
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=98.48  E-value=2.5e-11  Score=127.02  Aligned_cols=136  Identities=24%  Similarity=0.253  Sum_probs=93.8  Template_Neff=12.500

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.+|..++.........+...++++.+...+.+.++.++..++.++..++........
T Consensus       172 ~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~  251 (510)
T 6SA7_B          172 KKILKDLVKKLSSPNENELQNALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQ  251 (510)
T ss_dssp             HHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHTCHHHHHHHHHHTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHH
T ss_pred             HHHHHHHHHHhcCCChHHHHHHHHHHHHHhcCChHHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHH
Confidence            45666777777777788889999999998765544444444556788888888887888999999999998765443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .+...++++.+...+. +.++.++..++.++..++..... ...+.. ++++.|+.++.
T Consensus       252 ~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  309 (510)
T 6SA7_B          252 AVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  309 (510)
T ss_dssp             HHHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHHHcCcHHHHHHHcc-CCCHHHHHHHHHHHHHHhcCChHHHHHHHHcChHHHHHHHhc
Confidence            3444567777777775 55677888888888888754322 222222 56666666664


No 8
>4RV1_D Engineered Protein OR497; STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE; 2.573A {SYNTHETIC CONSTRUCT}
Probab=98.47  E-value=2.7e-11  Score=120.80  Aligned_cols=362  Identities=20%  Similarity=0.254  Sum_probs=220.3  Template_Neff=13.300

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..+..............++++.+...+.+.++.++..++.++..++...........
T Consensus         4 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   83 (420)
T 4RV1_D            4 VEKLVKLLTSTDSETQKEAARDLAEIASGPASAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIV   83 (420)
T ss_dssp             HHHHHHHHHCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHTTSCSCSSSHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHHHHCCHHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHHH
Confidence            44556666677788888999999888765433333333446677777888777788899999999888765433323333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ..++++.+...+. +.++.++..++.++..+..... ....+.. ++++.+..++..                .++++..
T Consensus        84 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~~~  146 (420)
T 4RV1_D           84 DAGGVEVLVKLLT-STDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTS----------------TDSEVQK  146 (420)
T ss_dssp             HTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTC----------------SCHHHHH
T ss_pred             HcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCChHHHHHHHHcCHHHHHHHHHhC----------------CCHHHHH
Confidence            3456677777776 5567788889999988876432 2222222 566666666542                1344444


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-....      +              .....+. ..+++..+...++.      .+..-...+..+|.++..
T Consensus       147 ~a~~~l~~l~~~~------~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~  199 (420)
T 4RV1_D          147 EAARALANIASGP------D--------------EAIKAIV-DAGGVEVLVKLLTS------TDSEVQKEAARALANIAS  199 (420)
T ss_dssp             HHHHHHHHHHTSC------H--------------HHHHHHH-HTTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHhcCC------H--------------HHHHHHH-HCCHHHHHHHHhcC------CCHHHHHHHHHHHHHHhC
Confidence            4443332211000      0              0000000 01333333333221      111111222222222211


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT  564 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV  564 (747)
                      ..                                                  ......+.+.++++.+...+. +.++.+
T Consensus       200 ~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~~~  228 (420)
T 4RV1_D          200 GP--------------------------------------------------TSAIKAIVDAGGVEVLVKLLT-STDSEV  228 (420)
T ss_dssp             SC--------------------------------------------------HHHHHHHHTTTHHHHHHHHTT-CSCHHH
T ss_pred             CC--------------------------------------------------HHHHHHHHHCCHHHHHHHHhh-CCCHHH
Confidence            00                                                  000111234456777888887 467788


Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL-L-HRVMGNQVFPEVTR  642 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-~-~~ll~~giI~~Ll~  642 (747)
                      +..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.... . ..+...++++.+..
T Consensus       229 ~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~  303 (420)
T 4RV1_D          229 QKEAARALANIASGPDE-----AIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVK  303 (420)
T ss_dssp             HHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHH
T ss_pred             HHHHHHHHHHHhCCCHH-----HHHHHhhccHHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHH
Confidence            88999999998864332     12233456788888888888888899999999999987632 2 23344467777888


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ++.+      .++.++..++.+|.+++...+.....+...+.++.+..++.+. ++.++..++.+|.+++...
T Consensus       304 ~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~  369 (420)
T 4RV1_D          304 LLTS------TDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTST-DSEVQKEAARALANIASGP  369 (420)
T ss_dssp             HTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHHHHHTSC
T ss_pred             HccC------CCHHHHHHHHHHHHHHHcChHHHHHHHHHCCHHHHHHHHhCCC-CHHHHHHHHHHHHHHHcCC
Confidence            7776      3678899999999999876444444455556788888888766 7889999999999998764


No 9
>6S9O_F designed Armadillo repeat protein with; peptide binder, repeat protein, designed; HET: CA, EDO; 3.17A {synthetic construct}
Probab=98.47  E-value=2.8e-11  Score=117.85  Aligned_cols=167  Identities=20%  Similarity=0.267  Sum_probs=122.0  Template_Neff=13.100

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.++.++. +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       170 ~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~  243 (344)
T 6S9O_F          170 DAGALPALVQLLS-SPNEQILQLALWALSNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIAS  243 (344)
T ss_dssp             HTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             hCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCChH-----HHHHHHhcChHHHHHHHccCCCHHHHHHHHHHHHHHHc
Confidence            4456777888887 46777888899999998864332     12333445788888888888888899999999999986


Q NP_000290.2     625 H-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      . ... ......++++.+..++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. ++.++.
T Consensus       244 ~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  316 (344)
T 6S9O_F          244 GGNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSHE-NEKIQK  316 (344)
T ss_dssp             SCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHH
T ss_pred             CcHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHhhCC-CHHHHH
Confidence            5 222 233445677778887766      3678889999999999876555555555556788888888766 788999


Q NP_000290.2     703 AARLLLSDMWSSKELQGVLRQQ  724 (747)
Q Consensus       703 aAL~aLsnL~~~~~~~~~~~~~  724 (747)
                      .++.+|.+++...+.....+..
T Consensus       317 ~a~~~l~~l~~~~~~~~~~~~~  338 (344)
T 6S9O_F          317 EAQEALEKLQSHGSGGSGKRKR  338 (344)
T ss_dssp             HHHHHHHHHHHCSCCCCCCCBC
T ss_pred             HHHHHHHHHHhcccCCCchhcc
Confidence            9999999998776654444333


No 10
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=98.46  E-value=3e-11  Score=116.21  Aligned_cols=318  Identities=20%  Similarity=0.263  Sum_probs=178.1  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+....+.....+...++++.+...+.+.++.++..++.++..+..........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~   84 (328)
T 5MFD_C            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV   84 (328)
T ss_dssp             CHHHHHHHHHSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHH
Confidence            45556666666777888889999988876544333334445677788888877778888889998888875433322223


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++..                .++++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~~  147 (328)
T 5MFD_C           85 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSS----------------PNEQIL  147 (328)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGC----------------SCHHHH
T ss_pred             hhcCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcC----------------CCHHHH
Confidence            33345666666665 4455666777777777665321 1111111 334444433321                011111


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..                                                                     ++..|.++.
T Consensus       148 ~~---------------------------------------------------------------------a~~~l~~l~  158 (328)
T 5MFD_C          148 QE---------------------------------------------------------------------ALWTLGNIA  158 (328)
T ss_dssp             HH---------------------------------------------------------------------HHHHHHHHT
T ss_pred             HH---------------------------------------------------------------------HHHHHHHHH
Confidence            11                                                                     111222221


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                  .....+.+.++++.++.++. +.++.
T Consensus       159 ~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~~~~  187 (328)
T 5MFD_C          159 SGGN--------------------------------------------------EQIQAVIDAGALPALVQLLS-SPNEQ  187 (328)
T ss_dssp             TSCH--------------------------------------------------HHHHHHHHTTHHHHHHHGGG-CSCHH
T ss_pred             cCCH--------------------------------------------------HHHHHHHHCCcHHHHHHHhc-CCCHH
Confidence            0000                                                  00000122345556666665 35556


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.++.+++.. +.. ......++++.+.
T Consensus       188 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~  262 (328)
T 5MFD_C          188 ILQEALWTLGNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALV  262 (328)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHH
Confidence            666777777777654221     122223445667777777666667777777777777654 222 2223345666666


Q NP_000290.2     642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       642 ~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      .++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. ++.++..++.+|.+++
T Consensus       263 ~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~  326 (328)
T 5MFD_C          263 QLLSS------PNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQSHE-NEKIQKEAQEALEKLQ  326 (328)
T ss_dssp             HGGGC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHHHHHH
T ss_pred             HHhcC------CCHHHHHHHHHHHHHHhCCcHHHHHHHHHCCHHHHHHHHhhCC-CHHHHHHHHHHHHHHh
Confidence            66655      2566777777777777765444444444445667777777655 6677777777777665


No 11
>4MZ6_E Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin; ARM repeat, protein transport, Importin; 1.88A {Mus musculus}
Probab=98.45  E-value=3.5e-11  Score=125.01  Aligned_cols=368  Identities=14%  Similarity=0.178  Sum_probs=227.8  Template_Neff=12.800

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAK-QQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~-~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ..+++.+...+.+.++.++..++.++..+........ ..+...++++.+...+...+ +.++..++.++..++......
T Consensus        56 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~  135 (509)
T 4MZ6_E           56 NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQ  135 (509)
T ss_dssp             TCCHHHHHHHHTTCCHHHHHHHHHHHHHHHTCSSCCCHHHHHHTTHHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHH
T ss_pred             hhhHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHH
Confidence            4456667777777788889999999988876433211 22333456777777776543 678888999998887654433


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.|+.++.....           +..+
T Consensus       136 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~-----------~~~~  203 (509)
T 4MZ6_E          136 TKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDL-----------STLA  203 (509)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTCSSCG-----------GGSC
T ss_pred             HHHHHhcChHHHHHHHhc-CCChhHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhCCCh-----------hhhh
Confidence            333444467777888886 56778889999999998875432 222223 677777777764211           1122


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++...+..+|..-.                     .............+++..+...+..      -+......+...|
T Consensus       204 ~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l  256 (509)
T 4MZ6_E          204 CGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWAI  256 (509)
T ss_dssp             HHHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh---------------------cCCCCCCCHHHHHHHHHHHHHHHhC------CCHHHHHHHHHHH
Confidence            333333333332211                     0000011111112334444333321      1111222222223


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++...-                                                  ......+.+.++++.|+.++. +
T Consensus       257 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  285 (509)
T 4MZ6_E          257 SYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-A  285 (509)
T ss_dssp             HHHTSSS--------------------------------------------------HHHHHHHHTTTCHHHHHHHHT-C
T ss_pred             HHHhcCC--------------------------------------------------hHHHHHHhhCChHHHHHHHhc-C
Confidence            3222100                                                  001112244567888888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. +.. ..+...+++
T Consensus       286 ~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~  360 (509)
T 4MZ6_E          286 TELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV  360 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHH
T ss_pred             CCcchHHHHHHHHHHHhcCCHH-----HHHHHHhCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHH
Confidence            6778888999999999875332     233334567888899999888889999999999999876 322 233445678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +.++.++.+      .++.++..++.+|.+++.. .+.....+.+.++++.|..++.+. ++.++..++.+|.+++.
T Consensus       361 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~  430 (509)
T 4MZ6_E          361 PFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHHHHHHS------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHHGGGCS-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCCHHHHHHHHhCC-CHHHHHHHHHHHHHHHH
Confidence            888888876      3678899999999999874 234444555556788888888876 78899999999999987


No 12
>5UMZ_B Importin subunit alpha-1, TNRC6A; mRNA decay, miRNA ARM repeat; HET: GOL; 1.9A {Mus musculus}
Probab=98.45  E-value=3.5e-11  Score=125.01  Aligned_cols=368  Identities=14%  Similarity=0.178  Sum_probs=227.8  Template_Neff=12.800

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAK-QQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~-~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ..+++.+...+.+.++.++..++.++..+........ ..+...++++.+...+...+ +.++..++.++..++......
T Consensus        56 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~  135 (509)
T 5UMZ_B           56 NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQ  135 (509)
T ss_dssp             SCCHHHHHHHHTSSCHHHHHHHHHHHHHHHTSSSCCCHHHHHHTTCHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHH
T ss_pred             hhhHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHH
Confidence            4456667777777788889999999988876433211 22333456777777776543 678888999998887654433


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.|+.++.....           +..+
T Consensus       136 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~-----------~~~~  203 (509)
T 5UMZ_B          136 TKAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDL-----------STLA  203 (509)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHTCHHHHHHHHHTTCHHHHHHHTCSSCG-----------GGSC
T ss_pred             HHHHHhcChHHHHHHHhc-CCChhHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhCCCh-----------hhhh
Confidence            333444467777888886 56778889999999998875432 222223 677777777764211           1122


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++...+..+|..-.                     .............+++..+...+..      -+......+...|
T Consensus       204 ~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l  256 (509)
T 5UMZ_B          204 CGYLRNLTWTLSNLC---------------------RNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWAI  256 (509)
T ss_dssp             HHHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTS------SCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh---------------------cCCCCCCCHHHHHHHHHHHHHHHhC------CCHHHHHHHHHHH
Confidence            333333333332211                     0000011111112334444333321      1111222222223


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++...-                                                  ......+.+.++++.|+.++. +
T Consensus       257 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  285 (509)
T 5UMZ_B          257 SYLTDGP--------------------------------------------------NERIEMVVKKGVVPQLVKLLG-A  285 (509)
T ss_dssp             HHHTSSC--------------------------------------------------HHHHHHHHTTTCHHHHHHHHT-C
T ss_pred             HHHhcCC--------------------------------------------------hHHHHHHhhCChHHHHHHHhc-C
Confidence            3222100                                                  001112244567888888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. +.. ..+...+++
T Consensus       286 ~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~  360 (509)
T 5UMZ_B          286 TELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLV  360 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHH
T ss_pred             CCcchHHHHHHHHHHHhcCCHH-----HHHHHHhCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHH
Confidence            6778888999999999875332     233334567888899999888889999999999999876 322 233445678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +.++.++.+      .++.++..++.+|.+++.. .+.....+.+.++++.|..++.+. ++.++..++.+|.+++.
T Consensus       361 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~  430 (509)
T 5UMZ_B          361 PFLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHHHHHHS------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHHGGGCS-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCCHHHHHHHHhCC-CHHHHHHHHHHHHHHHH
Confidence            888888876      3678899999999999874 234444555556788888888876 78899999999999987


No 13
>2JDQ_A IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC; TRANSPORT, PB2 SUBUNIT, NUCLEAR PROTEIN; 2.2A {HOMO SAPIENS}
Probab=98.45  E-value=3.6e-11  Score=122.13  Aligned_cols=367  Identities=14%  Similarity=0.163  Sum_probs=226.8  Template_Neff=13.000

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA--KQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~--~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      +.+++.+...+.+.++.++..++.+|..+.......  ...+...++++.+...+.. .++.++..++.++..++.....
T Consensus        19 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   98 (450)
T 2JDQ_A           19 GVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSL   98 (450)
T ss_dssp             ---CHHHHHHHHSSCHHHHHHHHHHHHHHHHSSSSCCHHHHHTSTTHHHHHHHHHTCTTCHHHHHHHHHHHHHHHSSCHH
T ss_pred             CcccHHHHHHHhcCCHHHHHHHHHHHHHHHccCCCCCHhHHhcCcchHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCcH
Confidence            445567777788788889999999999887532211  1222224667777777765 5677888899999888765443


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.++.++...               .
T Consensus        99 ~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~  162 (450)
T 2JDQ_A           99 QTRIVIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ---------------N  162 (450)
T ss_dssp             HHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSC---------------C
T ss_pred             HHHHHHHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChHHHHHHHHCCCHHHHHHHHhhc---------------c
Confidence            3333333467777888876 5567888899999998887543 2223333 6777777776431               1


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..++..-..                     ............+++..+...+..      -+..-...+...
T Consensus       163 ~~~~~~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  215 (450)
T 2JDQ_A          163 RLTMTRNAVWALSNLCR---------------------GKSPPPEFAKVSPCLNVLSWLLFV------SDTDVLADACWA  215 (450)
T ss_dssp             CHHHHHHHHHHHHHHHC---------------------CSSSCCCGGGTGGGHHHHHHHTTC------CCHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHhc---------------------CCCCCchhhhhhhHHHHHHHHhcC------CCHHHHHHHHHH
Confidence            23443344333322110                     000111111222333333332221      111122222223


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       216 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  244 (450)
T 2JDQ_A          216 LSYLSDGP--------------------------------------------------NDKIQAVIDAGVCRRLVELLM-  244 (450)
T ss_dssp             HHHHTSSS--------------------------------------------------HHHHHHHHHTTTHHHHHHHTT-
T ss_pred             HHHHhcCC--------------------------------------------------HHHHHHHHHCCHHHHHHHHHc-
Confidence            33222110                                                  001112245567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+.+.++++.+..++.+.++.++..++.+|.+++... .. ......++
T Consensus       245 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~  319 (450)
T 2JDQ_A          245 HNDYKVVSPALRAVGNIVTGDDI-----QTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANI  319 (450)
T ss_dssp             CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHTTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTH
T ss_pred             CCCHHHHHHHHHHHHHHhhCChH-----HHHHHhhcchHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCH
Confidence            46778888999999999875332     2233345578888999998888889999999999998762 22 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQ-PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ++.+..++.+      .++.++..++.+|.+++... +.....+.+.++++.+..++.+. ++.++..++.+|.+++...
T Consensus       320 ~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  392 (450)
T 2JDQ_A          320 FPALISILQT------AEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVM-DSKIVQVALNGLENILRLG  392 (450)
T ss_dssp             HHHHHHHHHH------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhc------CCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHHHHHHHhhCC-CHHHHHHHHHHHHHHHHHh
Confidence            8888888876      36788899999999998752 34445555556788888888876 7889999999999998765


Q NP_000290.2     716 E  716 (747)
Q Consensus       716 ~  716 (747)
                      +
T Consensus       393 ~  393 (450)
T 2JDQ_A          393 E  393 (450)
T ss_dssp             H
T ss_pred             H
Confidence            4


No 14
>4E4V_A Importin subunit alpha-2; armadillo repeat, karyopherin, importin, nuclear; HET: GOL, DTT; 2.5283A {Homo sapiens}
Probab=98.45  E-value=3.6e-11  Score=124.32  Aligned_cols=364  Identities=17%  Similarity=0.189  Sum_probs=218.6  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus        76 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  155 (485)
T 4E4V_A           76 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSVFRDL  155 (485)
T ss_dssp             CHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhcCCCChHHHHHHHHHHHHHhcCChHHHHHHHhcChHHHHHHHhcCCChhHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665443 678888889988887654433334444567778888888777888999999999888654432333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNA-----EIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~-----eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. ....     .++..++.++..++..........  .++++.+..++..                
T Consensus       156 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  218 (485)
T 4E4V_A          156 VIKYGAVDPLLALLA-VPDMSSLACGYLRNLTWTLSNLCRNKNPAPPIDAVEQILPTLVRLLHH----------------  218 (485)
T ss_dssp             HHHTTCHHHHHHTTC-SSCGGGSCHHHHHHHHHHHHHHTCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHHh-CCCcccchHHHHHHHHHHHHHHHhCCCCCCCHHHHhcHHHHHHHHhcC----------------
Confidence            333456666776665 2222     567778888888876443222222  2556666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..+|..-..                     .+......---.+++..|...+..      .+..-...+..
T Consensus       219 ~~~~~~~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~  271 (485)
T 4E4V_A          219 DDPEVLADTCWAISYLTD---------------------GPNERIGMVVKTGVVPQLVKLLGA------SELPIVTPALR  271 (485)
T ss_dssp             CCHHHHHHHHHHHHHHTS---------------------SCHHHHHHHHTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhc---------------------CChHHhhHHhhCChHHHHHHHhcC------CChHHHHHHHH
Confidence            134444444444432110                     000000000012233333333221      11222223333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.++...-                                                  ......+.+.++++.|+.++.
T Consensus       272 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  301 (485)
T 4E4V_A          272 AIGNIVTGT--------------------------------------------------DEQTQVVIDAGALAVFPSLLT  301 (485)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHHT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHhCChHHHHHHHhc
Confidence            333332100                                                  001112234567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|+.++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       302 -~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~  375 (485)
T 4E4V_A          302 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVYLVHC  375 (485)
T ss_dssp             -CSSHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHcCCCHH-----HHHHHHHCCHHHHHHHHHhcCCHHHHHHHHHHHHHHHhcCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899999888888999999999999875 2 12 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQ------PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s------~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++...      +.....+.+.++++.|..++.+. ++.++..++.+|
T Consensus       376 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  448 (485)
T 4E4V_A          376 GIIEPLMNLLTA------KDTKIILVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQNHE-NESVYRASLSLI  448 (485)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHTTCHHHHHHHHHHTTHHHHHHTTCCTT-SHHHHHHHHHHH
T ss_pred             CcHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhCChhHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            677888888776      36788999999999998731      22333344456788888888766 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      .+++...+
T Consensus       449 ~~l~~~~~  456 (485)
T 4E4V_A          449 EKYFSVEE  456 (485)
T ss_dssp             HHHCC---
T ss_pred             HHHcCccc
Confidence            99986543


No 15
>4B18_A IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE; TRANSPORT PROTEIN - PEPTIDE COMPLEX; 2.52A {HOMO SAPIENS}
Probab=98.44  E-value=4e-11  Score=121.64  Aligned_cols=368  Identities=14%  Similarity=0.162  Sum_probs=227.4  Template_Neff=13.000

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES--AKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~--~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      +.+++.+...+.+.++.++..++.+|..+......  ....+...++++.+...+.. .++.++..++.++..++.....
T Consensus        16 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~   95 (447)
T 4B18_A           16 GVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDEVISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSL   95 (447)
T ss_dssp             CSSCHHHHHHHTSSCHHHHHHHHHHHHHHHHCSSCCCHHHHHTSTTHHHHHHHHTTCTTCHHHHHHHHHHHHHHTSSCHH
T ss_pred             CCCcHHHHHHHhcCCHHHHHHHHHHHHHHhCCCCCCCHhHHhcCccHHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCcH
Confidence            44556677777777888899999999888753221  11222224667777777765 5677888899999888765433


Q NP_000290.2     321 NKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       321 ~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                      ....+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .
T Consensus        96 ~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~  159 (447)
T 4B18_A           96 QTRIVIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ---------------N  159 (447)
T ss_dssp             HHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGCT---------------T
T ss_pred             HHHHHHHcChHHHHHHHhh-CCCHHHHHHHHHHHHHHHccChhHHHHHHHCCcHHHHHHHhhcC---------------C
Confidence            3223333467777888776 5567888899999998887543 2223333 6677777766431               1


Q NP_000290.2     399 DPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCV  478 (747)
Q Consensus       399 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  478 (747)
                      ++++...+..+|..-.                     .............+++..+...++.      -+......+...
T Consensus       160 ~~~~~~~~~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~  212 (447)
T 4B18_A          160 RLTMTRNAVWALSNLC---------------------RGKSPPPEFAKVSPCLNVLSWLLFV------SDTDVLADACWA  212 (447)
T ss_dssp             CHHHHHHHHHHHHHHH---------------------CCSSSCCCHHHHGGGHHHHHHHTTS------CCHHHHHHHHHH
T ss_pred             ChhHHHHHHHHHHHHh---------------------cCCCCCCcccccccHHHHHHHHhhC------CCHHHHHHHHHH
Confidence            2344333333332211                     0000111111122333333322211      111112222222


Q NP_000290.2     479 LHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK  558 (747)
Q Consensus       479 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s  558 (747)
                      |.++...-                                                  ......+.+.++++.++.++. 
T Consensus       213 l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-  241 (447)
T 4B18_A          213 LSYLSDGP--------------------------------------------------NDKIQAVIDAGVCRRLVELLM-  241 (447)
T ss_dssp             HHHHTSSS--------------------------------------------------HHHHHHHHHTTCHHHHHHHTT-
T ss_pred             HHHHhcCC--------------------------------------------------HHHHHHHHHCCHHHHHHHHHc-
Confidence            32222100                                                  001112245567888888887 


Q NP_000290.2     559 SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQV  636 (747)
Q Consensus       559 s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~gi  636 (747)
                      +.++.++..++.+|.+++...+.     ....+.+.++++.|..++.+.++.++..++.+|.+++... .. ......++
T Consensus       242 ~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~  316 (447)
T 4B18_A          242 HNDYKVVSPALRAVGNIVTGDDI-----QTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTVIDANI  316 (447)
T ss_dssp             CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTH
T ss_pred             CCCHHHHHHHHHHHHHHhcCChH-----HHHHHhhcchHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCh
Confidence            46778888999999999875332     2233345578888999998888889999999999998762 22 23344567


Q NP_000290.2     637 FPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       637 I~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ++.+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++...
T Consensus       317 ~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  389 (447)
T 4B18_A          317 FPALISILQT------AEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLTVM-DSKIVQVALNGLENILRLG  389 (447)
T ss_dssp             HHHHHHHHHH------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhc------CCHHHHHHHHHHHHHHhccCCHHHHHHHHHCCcHHHHHHHhhCC-CHHHHHHHHHHHHHHHHHh
Confidence            8888888876      3678899999999999875 234445555556788888888876 7889999999999998765


Q NP_000290.2     716 EL  717 (747)
Q Consensus       716 ~~  717 (747)
                      +.
T Consensus       390 ~~  391 (447)
T 4B18_A          390 EQ  391 (447)
T ss_dssp             HH
T ss_pred             HH
Confidence            43


No 16
>4XZR_B Heh1-NLS, Kap60; karyopherins  nuclear import ; 2.25A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=98.43  E-value=4.3e-11  Score=119.82  Aligned_cols=363  Identities=16%  Similarity=0.214  Sum_probs=223.0  Template_Neff=13.200

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +.+...+.+.++.++..++..+..++..... ........++++.+...+...+ +.++..++.++..++.........+
T Consensus         4 ~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~   83 (423)
T 4XZR_B            4 PQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVV   83 (423)
T ss_dssp             SSSSTTTSSSCHHHHHHHHHHHHHHHSCSSSCCHHHHHTTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hhHhhhcChHhHHHHHHHHHHHHHHHcCCCCCchHHHHhCCcHHHHHHHhhCCCCHHHHHHHHHHHHHHhCCCchhhhHH
Confidence            4455566667777888888888877654321 1222333466777777776543 6778889999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+. +.++.++..++.++..++... .....+.. ++++.|..++...                ++++.
T Consensus        84 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  146 (423)
T 4XZR_B           84 VDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN----------------KPSLI  146 (423)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSC----------------CHHHH
T ss_pred             cccchHHHHHHHHh-CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHHhcC----------------CHHHH
Confidence            33467777777776 567788899999999988753 22233333 6677777766521                34444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..                     .........-..+.++.|...++.      .+......+...|.++.
T Consensus       147 ~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~  199 (423)
T 4XZR_B          147 RTATWTLSNLCR---------------------GKKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACWAISYLS  199 (423)
T ss_dssp             HHHHHHHHHHHC---------------------CCTTCCCHHHHGGGHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc---------------------CCCCCCChHHhccHHHHHHHHhhC------CCHHHHHHHHHHHHHHh
Confidence            444444432111                     000001111122334444333321      11112222222333322


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..                                                  +......+.+.++++.++.++. +.++.
T Consensus       200 ~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~-~~~~~  228 (423)
T 4XZR_B          200 DG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS-HESTL  228 (423)
T ss_dssp             SS--------------------------------------------------SHHHHHHHHHTTHHHHHHHHTT-CSCHH
T ss_pred             cC--------------------------------------------------CHHHHHHHHhcCHHHHHHHHhc-CCCHH
Confidence            11                                                  0011122345567888888887 46778


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++... .. ..+...++++.+.
T Consensus       229 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~  303 (423)
T 4XZR_B          229 VQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLV  303 (423)
T ss_dssp             HHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHH
Confidence            888999999999865332     2223334578888888888888889999999999998762 22 3334556778888


Q NP_000290.2     642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQP---QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       642 ~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~---e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      .++.+      .++.++..++.+|.+++....   .....+.+.++++.+..++.+. ++.++..++.+|.+++...+.
T Consensus       304 ~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~~~~  375 (423)
T 4XZR_B          304 KLLEV------AEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENILKMGEA  375 (423)
T ss_dssp             HHHHH------SCHHHHHHHHHHHHHHHHGGGTCHHHHHHHHHTTCHHHHHHHTTTS-CHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHh------CCchHHHHHHHHHHHHHhCCCCCHHHHHHHHHCCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHHHH
Confidence            88866      367889999999999987532   2234445556788888888876 788899999999999876554


No 17
>5XZX_A Importin subunit alpha-3, Ran-binding protein; nuclear import, TRANSPORT PROTEIN; 3.0A {Homo sapiens}
Probab=98.43  E-value=4.3e-11  Score=119.52  Aligned_cols=133  Identities=19%  Similarity=0.169  Sum_probs=87.0  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++.+...+.+.++.++..++.+|..+...... ....+...++++.+...+. ..++.++..++.++..++.........
T Consensus         4 ~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~   83 (416)
T 5XZX_A            4 LEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQA   83 (416)
T ss_dssp             HHHHHHHTTCSSHHHHHHHHHHHHHTTSSSSSCCHHHHHTTTCHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             HHHHHHHHhcCCHHHHHHHHHHHHHHHhCCCCCCHHHHHHcCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCChHHHHH
Confidence            44566666677778888999999888764321 1122333456777777776 456778888899998887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~  380 (747)
                      +...++++.+...+. +.++.++..++.++..++... .....+.. ++++.|..++.
T Consensus        84 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  140 (416)
T 5XZX_A           84 VVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFIS  140 (416)
T ss_dssp             HHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHHTCHHHHTTSCS
T ss_pred             HHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCccHHHHHHhcC
Confidence            334457777777776 567788899999999988652 22222333 66677776664


No 18
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=98.42  E-value=4.4e-11  Score=123.86  Aligned_cols=378  Identities=19%  Similarity=0.226  Sum_probs=227.0  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.++.++..++.++..++.........
T Consensus       101 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  180 (529)
T 1JDH_A          101 GGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLI  180 (529)
T ss_dssp             THHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCTTHHHHHHHHTHHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             CCHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCcchHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            34556666666667788888999998887654333333334567777888887777888899999999888544433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...++++.+...+....+..++..++.++..+.........+.. ++++.+..++...                ++++.
T Consensus       181 ~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~  244 (529)
T 1JDH_A          181 ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLV  244 (529)
T ss_dssp             HHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHTTTTSS----------------CHHHH
T ss_pred             HHHCChhHHHHHHHccCCcHHHHHHHHHHHHHHhcCCccHHHHHHCCHHHHHHHHccCC----------------CHHHH
Confidence            444457777777776333567888888888888875443333333 6667776666432                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     ........+   .+++..+...++.      -+..-...+...|.++.
T Consensus       245 ~~~~~~l~~l~---------------------~~~~~~~~~---~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  294 (529)
T 1JDH_A          245 QNCLWTLRNLS---------------------DAATKQEGM---EGLLGTLVQLLGS------DDINVVTCAAGILSNLT  294 (529)
T ss_dssp             HHHHHHHHHHH---------------------TTCTTCSCC---HHHHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHc---------------------chhhhHHHH---chHHHHHHHHhCC------CCHHHHHHHHHHHHHHh
Confidence            33333332110                     000000001   2334444333321      11111222223333332


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKD  562 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~  562 (747)
                      ...                                                  ......+.+.++++.++..+.. ..++
T Consensus       295 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  324 (529)
T 1JDH_A          295 CNN--------------------------------------------------YKNKMMVCQVGGIEALVRTVLRAGDRE  324 (529)
T ss_dssp             TTC--------------------------------------------------HHHHHHHHHTTHHHHHHHHHHHHTTCH
T ss_pred             cCC--------------------------------------------------HHHHHHHHHcCHHHHHHHHHHhcCCCh
Confidence            110                                                  0001112345667777776641 2456


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++.....  .......+...++++.+..++.+. ++.++..++.+|.+++..... ..+...++++.+
T Consensus       325 ~~~~~a~~~l~~l~~~~~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l  402 (529)
T 1JDH_A          325 DITEPAICALRHLTSRHQE--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRL  402 (529)
T ss_dssp             HHHHHHHHHHHHHTSSSTT--HHHHHHHHHHTTCHHHHHHTTSTTCCHHHHHHHHHHHHHHTTSGGGHHHHHHTTHHHHH
T ss_pred             HhHHHHHHHHHHHhcCccc--HHHHHHHHHhcccHHHHHHHHCCCCCHHHHHHHHHHHHHHhcChhhhHHHHhcCHHHHH
Confidence            7788899999998865331  000012222456788888888765 678899999999999876433 334455677888


Q NP_000290.2     641 TRLLTSHTGNTSNS--------------------EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       641 l~LL~s~s~~~~~d--------------------~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ..++....    .+                    +.++..++.+|.+++.. ......+...++++.++.++.+. ++.+
T Consensus       403 ~~~l~~~~----~~~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~~  476 (529)
T 1JDH_A          403 VQLLVRAH----QDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARD-VHNRIVIRGLNTIPLFVQLLYSP-IENI  476 (529)
T ss_dssp             HHHHHHHH----HHHC-----------CBTTBCHHHHHHHHHHHHHHHTTS-HHHHHHHHHTTCHHHHHHGGGCS-CHHH
T ss_pred             HHHHHhcC----hhHHHHHhccCcchhHhccCCHHHHHHHHHHHHHHHhcC-ccchHHHHhcCcHHHHHHHhcCC-CHHH
Confidence            88876520    01                    67888999999999875 34444455556788888888876 7889


Q NP_000290.2     701 AEAARLLLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       701 r~aAL~aLsnL~~~~~~~~~~~~~~~  726 (747)
                      +..++.+|.+++...+....+...|+
T Consensus       477 ~~~a~~~l~~l~~~~~~~~~~~~~~~  502 (529)
T 1JDH_A          477 QRVAAGVLCELAQDKEAAEAIEAEGA  502 (529)
T ss_dssp             HHHHHHHHHHHTTSHHHHHHHHHTTC
T ss_pred             HHHHHHHHHHHhcCHHHHHHHHHcCc
Confidence            99999999999987765544444443


No 19
>3IFQ_A plakoglobin, E-cadherin; armadillo repeat, Cardiomyopathy, Cell adhesion; HET: SO4; 2.8A {Homo sapiens}
Probab=98.42  E-value=4.5e-11  Score=124.53  Aligned_cols=381  Identities=19%  Similarity=0.234  Sum_probs=227.1  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++.........+...++++.+...+.+.++.++..++.++..++.........+
T Consensus       104 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  183 (553)
T 3IFQ_A          104 GIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLII  183 (553)
T ss_dssp             HHHHHHHGGGCCCHHHHHHHHHHHHHHHHHCTTHHHHHHHTTGGGGTGGGGGSSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHhcCChHHHHHHHhcCHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677888889999988876543333333335677788888877778888999999998876444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+....+..++..++.++..+.........+.. ++++.+..++...                ++++..
T Consensus       184 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  247 (553)
T 3IFQ_A          184 LANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSN----------------SPRLVQ  247 (553)
T ss_dssp             HHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHGGGGSS----------------CHHHHH
T ss_pred             HHCCHHHHHHHHHhcCCcHHHHHHHHHHHHHHhCCcchHHHHHHCchHHHHHHHHhcC----------------CHHHHH
Confidence            34456777777776333567888888888888775444333443 6667777666531                233333


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-..                     ......   ...++++.+...++.      .+..-...+...|.++..
T Consensus       248 ~a~~~l~~l~~---------------------~~~~~~---~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~  297 (553)
T 3IFQ_A          248 NCLWTLRNLSD---------------------VATKQE---GLESVLKILVNQLSV------DDVNVLTCATGTLSNLTC  297 (553)
T ss_dssp             HHHHHHHHHHT---------------------TCTTCS---CCHHHHHHHHTTTTC------CCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhCC---------------------hhHHHH---HHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHc
Confidence            33333322110                     000011   112344444433321      111222233333333321


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKDA  563 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~e  563 (747)
                      ...                                                  .....+.+.++++.++..+.. ..++.
T Consensus       298 ~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~~~~~~~~  327 (553)
T 3IFQ_A          298 NNS--------------------------------------------------KNKTLVTQNSGVEALIHAILRAGDKDD  327 (553)
T ss_dssp             TCH--------------------------------------------------HHHHHHTTTTHHHHHHHHHHHHTTCHH
T ss_pred             CCH--------------------------------------------------HHHHHHHHccHHHHHHHHHHHcCCChH
Confidence            100                                                  001122345677777776652 14566


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN-SDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d-~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++..... ... ....+...++++.+..++.+.+ +.++..++.+|.+++..... ......++++.+.
T Consensus       328 ~~~~a~~~l~~l~~~~~~-~~~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~  405 (553)
T 3IFQ_A          328 ITEPAVCALRHLTSRHPE-AEM-AQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLV  405 (553)
T ss_dssp             HHHHHHHHHHHHTSSSTT-HHH-HHHHHHTTTHHHHHHHGGGCTTCHHHHHHHHHHHHHHTTSGGGHHHHHHTTHHHHHH
T ss_pred             hHHHHHHHHHHHhcCCCh-HHH-HHHHHHHcchHHHHHHHHcCCCChHHHHHHHHHHHHHhcCcccHHHHHHccHHHHHH
Confidence            788889999998865321 000 0112234567888888887654 78889999999999876433 2334456778888


Q NP_000290.2     642 RLLTSHTGN---------------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       642 ~LL~s~s~~---------------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .++......               ......++..++.+|.+++.. +.....+...++++.++.++.+. ++.++..++.
T Consensus       406 ~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~  483 (553)
T 3IFQ_A          406 QLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHILARD-PMNRMEIFRLNTIPLFVQLLYSS-VENIQRVAAG  483 (553)
T ss_dssp             HHHHHHHHHHHHHHHTTCCCTTCSSCCHHHHHHHHHHHHHHHTTS-HHHHHHHHHTTCHHHHHHHTTCS-CHHHHHHHHH
T ss_pred             HHHHHcCcchhHHHhhcccCccccCCCHHHHHHHHHHHHHHHhcC-hhhHHHHHHcCChHHHHHHHhCC-CHHHHHHHHH
Confidence            877652100               000027788899999999874 44445555667888888888866 7889999999


Q NP_000290.2     707 LLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       707 aLsnL~~~~~~~~~~~~~~~  726 (747)
                      +|.+++...+....+.+.|.
T Consensus       484 ~l~~l~~~~~~~~~~~~~~~  503 (553)
T 3IFQ_A          484 VLCELAQDKEAADAIDAEGA  503 (553)
T ss_dssp             HHHHHTTSHHHHHHHHHTTT
T ss_pred             HHHHHHcCHHHHHHHHHCCc
Confidence            99999987766555554443


No 20
>4UAD_A Importin alpha import adaptor, Influenza; importin karyopherin complex NLS, PROTEIN; 2.42A {Homo sapiens}
Probab=98.39  E-value=6e-11  Score=121.78  Aligned_cols=372  Identities=17%  Similarity=0.175  Sum_probs=218.3  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+ .++.++..++.++..++.........+...++++.+..++.+.+..++..++.++..++.........
T Consensus        68 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  147 (479)
T 4UAD_A           68 VVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDY  147 (479)
T ss_dssp             HHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             hHHHHHHHhhcCCCHHHHHHHHHHHHHHhCCCchHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHH
Confidence            45556666654 56778888899998887654333333333567777888887777888899999999887654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI-A-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv-e-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....++.++..++.++..++.......... . ++++.++.++...                ++++
T Consensus       148 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~  211 (479)
T 4UAD_A          148 VLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSS----------------DSDL  211 (479)
T ss_dssp             HHHTTCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCSSCCCGGGTGGGHHHHHHHTTCC----------------CHHH
T ss_pred             HHhCCcHHHHHHHhhcCCchHHHHHHHHHHHHHHcCCCCCchhhcccchHHHHHHHhcCC----------------CHHH
Confidence            33345666677766533456788888888888876542222222 1 5666666666431                2333


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      -..+..++..-...      .+              ...+.+ .-.+.+..|...++.      .+..-...+...|.++
T Consensus       212 ~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l  264 (479)
T 4UAD_A          212 LADACWALSYLSDG------PN--------------EKIQAV-IDSGVCRRLVELLMH------NDYKVASPALRAVGNI  264 (479)
T ss_dssp             HHHHHHHHHHHTSS------SH--------------HHHHHH-HHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhcC------ch--------------HHHHHH-HhCCHHHHHHHHhcC------CCHHhHHHHHHHHHHH
Confidence            33333333221100      00              000000 012333333333221      0111111222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ....                                                  ......+.+.++++.|+.++. +.++
T Consensus       265 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  293 (479)
T 4UAD_A          265 VTGD--------------------------------------------------DIQTQVILNCSALPCLLHLLS-SPKE  293 (479)
T ss_dssp             TTSC--------------------------------------------------HHHHHHHHTTTCHHHHHHHTT-CSSH
T ss_pred             hcCC--------------------------------------------------HHHHHHHHhcChHHHHHHHhh-CCCH
Confidence            2100                                                  000112234567888888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+.+.++++.|..++.+.++.++..++.+|.+++..  ... ..+...++++.
T Consensus       294 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  368 (479)
T 4UAD_A          294 SIRKEACWTISNITAGNRA-----QIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKP  368 (479)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHH
T ss_pred             HHHHHHHHHHHHHHcCCHH-----HHHHHHHCCHHHHHHHHHhccCHHHHHHHHHHHHHHHcCCCHHHHHHHHHcCcHHH
Confidence            8888999999999865332     223334557888999999888889999999999999874  222 23344567788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQ-----------YFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~-----------Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      +..++.+      .++.++..++.+|.+++...+.....           +.+.+.++.+..++.+. ++.++..++.+|
T Consensus       369 l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~-~~~v~~~a~~~l  441 (479)
T 4UAD_A          369 LCDLLTV------MDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHE-NQEIYQKAFDLI  441 (479)
T ss_dssp             HHGGGGC------SCHHHHHHHHHHHHHHHHHHHHHTTTTSCCCCTTHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHH
T ss_pred             HHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhcccCCCCcCHHHHHHHHhchHHHHHHHHhCC-cHHHHHHHHHHH
Confidence            8888776      36788889999999998753322111           34445677888888766 788999999999


Q NP_000290.2     709 SDMWSSKELQGVLRQ  723 (747)
Q Consensus       709 snL~~~~~~~~~~~~  723 (747)
                      .+++...+....+.+
T Consensus       442 ~~l~~~~~~~~~~~~  456 (479)
T 4UAD_A          442 EHYFGVEDDDSSLAP  456 (479)
T ss_dssp             HHHSCC---------
T ss_pred             HHhhCCCCCchhccc
Confidence            999977665554443


No 21
>5ZHX_D Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF chaperone, ONCOPROTEIN; HET: FAR; 3.5A {Homo sapiens}
Probab=98.39  E-value=6.3e-11  Score=120.93  Aligned_cols=407  Identities=17%  Similarity=0.217  Sum_probs=228.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP--NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~--d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+..++...  ++.++..++.++..++.... ...
T Consensus        19 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~v~~~a~~~l~~l~~~~~-~~~   97 (487)
T 5ZHX_D           19 LISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELES-SKE   97 (487)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHTTSTTCHHHHHHHHHTTCHHHHHHHHHHTSSCSHHHHHHHHHHHHHTTSSH-HHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHHcccCCCHHHHHHHHHHHHHHHcchh-HHH
Confidence            556677777777888999999999998875544444444556778888888765  77888899999998876532 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      .+...++++.+...+....++.++..++.++..++........+.. ++++.|..++.......         .....+.
T Consensus        98 ~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~---------~~~~~~~  168 (487)
T 5ZHX_D           98 QFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSD---------KEDDITE  168 (487)
T ss_dssp             HHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHHTSHHHHHHHHHHTHHHHHHHHHHHTSSCC---------CHHHHHH
T ss_pred             HHhhCCHHHHHHHHHHhccChHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHHHhcCCCC---------CHHHHHH
Confidence            3334467777888776222677888899999998876444444444 67777777776432100         0000000


Q NP_000290.2     403 FFNATGCLR----------KRL------GMRELLALVPQ-------RATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       403 ~~~~~~~~~----------~~~------~~~~~~~~~~~-------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      +..+...+.          +-+      -+..++.+...       .+...-.+++..+..+..+.. .+.++.+...+.
T Consensus       169 l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~  247 (487)
T 5ZHX_D          169 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVD-NGIVEKLMDLLD  247 (487)
T ss_dssp             HHHHHHHHHHHTTSHHHHHHHSSSSSSSHHHHHHTTTTSSCHHHHHHHHHHHHHHCCSHHHHHHHHT-TTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhccHHHHHHhhCCCchHHHHHHHHccCCCHHHHHHHHHHHHHHHcCchHHHHHHh-cCHHHHHHHHHH
Confidence            000000000          000      00111111100       000000011111111111000 011222211111


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ....  .-+..-...+..+|.|+.                                   ..               . ..
T Consensus       248 ~~~~--~~~~~~~~~a~~~l~~l~-----------------------------------~~---------------~-~~  274 (487)
T 5ZHX_D          248 RHVE--DGNVTVQHAALSALRNLA-----------------------------------IP---------------V-IN  274 (487)
T ss_dssp             HTSS--SSCHHHHHHHHHHHHHHT-----------------------------------CS---------------H-HH
T ss_pred             hccc--CCCHHHHHHHHHHHHHhc-----------------------------------CC---------------h-hh
Confidence            0000  000000111111111111                                   00               0 01


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASL  618 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-eVr~~AL~a  618 (747)
                      ...+.+.++++.++.++. +.++.++..++++|.+++...+.   . ........++++.++.++.+.+. .++..++++
T Consensus       275 ~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~---~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~  349 (487)
T 5ZHX_D          275 KAKMLSAGVTEAVLKFLK-SEMPPVQFKLLGTLRMLIDAQAE---A-AEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL  349 (487)
T ss_dssp             HHHHHHHTHHHHHHTTSS-CCCHHHHHHHHHHHHHHTSSCHH---H-HHHHHHCHHHHHHHHHHHTCCSCCHHHHHHHHH
T ss_pred             HHHHHHcChHHHHHHHHh-CCCHHHHHHHHHHHHHHHhhcHH---H-HHHhccccCHHHHHHHHHHhcCchhhHHHHHHH
Confidence            122345678888888888 46788888999999999875332   1 11221224678888888887665 888999999


Q NP_000290.2     619 LSNMSRHPL---L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       619 LsnLa~~~e---~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~  693 (747)
                      |.+++....   . ..+...++++.+..++..      .++.++..++.+|.+++...+ .....+.+.++++.++.++.
T Consensus       350 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  423 (487)
T 5ZHX_D          350 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATS------EHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLLA  423 (487)
T ss_dssp             HHHHHHHHCCHHHHHHHHHHTCHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTHHHHHHHHTS
T ss_pred             HHHHHHHhcchhHHHHHHHcchHHHHHHHhcC------CCHHHHHHHHHHHHHHHHcCCCchHHHHhhhhHHHHHHHHHh
Confidence            999986522   2 233445677888888776      367889999999999987542 23333444457888888887


Q NP_000290.2     694 SS-ASPKAAEAARLLLSDMWSSKELQGVLRQQGFD  727 (747)
Q Consensus       694 s~-~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~~~  727 (747)
                      .. .++.++..++.+|.+++...+....+...|+-
T Consensus       424 ~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~  458 (487)
T 5ZHX_D          424 DERSAPEIKYNSMVLICALMGSECLHKEVQDLAFL  458 (487)
T ss_dssp             SSCCSTTCTHHHHHHHHTSCSSSCCSTTTTTHHHH
T ss_pred             cccCcHHHHHHHHHHHHHHhCcHHHHHHHHHhchH
Confidence            32 15788999999999999887766666555543


No 22
>1EE4_A KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=98.36  E-value=8.2e-11  Score=117.69  Aligned_cols=364  Identities=16%  Similarity=0.224  Sum_probs=221.8  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++.+...+.+.++.++..++..+..++..... ....+...++++.+...+...+ +.++..++.++..++.........
T Consensus         3 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~   82 (423)
T 1EE4_A            3 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKV   82 (423)
T ss_dssp             HHHHHHHHTCSCHHHHHHHHHHHHHHHCCSSSCSHHHHHHTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             hHHHHHHhccccHHHHHHHHHHHHHHHhCCCCCchHHHHhcChHHHHHHHhhcCCcHHHHHHHHHHHHHHhCCCHHHHHH
Confidence            44566666777788888888888888754321 2222333456777777776543 667888899998887644333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|..++...                ++++
T Consensus        83 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~  145 (423)
T 1EE4_A           83 VVDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN----------------KPSL  145 (423)
T ss_dssp             HHHTTHHHHHHHHHH-HSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSC----------------CHHH
T ss_pred             HHhCChHHHHHHHHh-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcC----------------CHHH
Confidence            333456777777776 5677888899999998886532 2223333 6667776666421                2344


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      -..+..++..-...                     ...........+++..|...+..      .+......+...|.++
T Consensus       146 ~~~a~~~l~~l~~~---------------------~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l  198 (423)
T 1EE4_A          146 IRTATWTLSNLCRG---------------------KKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACWAISYL  198 (423)
T ss_dssp             HHHHHHHHHHHHCC---------------------STTCCCHHHHGGGHHHHHHHTTC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHcC---------------------CCCCCChHHHhhHHHHHHHHHHc------CCHHHHHHHHHHHHHH
Confidence            44444443321100                     00000111122334433333221      1111112222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...                                                  +......+.+.++++.+..++. +.++
T Consensus       199 ~~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~-~~~~  227 (423)
T 1EE4_A          199 SDG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS-HEST  227 (423)
T ss_dssp             TSS--------------------------------------------------CHHHHHHHHHTTHHHHHHHHTT-CSCH
T ss_pred             hcC--------------------------------------------------CHHHHHHHHhcCHHHHHHHHhc-CCCc
Confidence            110                                                  0001112234567778888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++++.+
T Consensus       228 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l  302 (423)
T 1EE4_A          228 LVQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL  302 (423)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHH
T ss_pred             chhHHHHHHHHHHHhCChH-----HHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHH
Confidence            8888999999998865332     122333457888888888888888999999999999875 222 334455677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQ---PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s---~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      ..++.+      .++.++..++.+|.+++...   +.....+.+.++++.+..++.+. ++.++..++.+|.+++...+.
T Consensus       303 ~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~~~  375 (423)
T 1EE4_A          303 VKLLEV------AEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENILKMGEA  375 (423)
T ss_dssp             HHHHHH------SCHHHHHHHHHHHHHHHGGGGTCHHHHHHHHHTTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHhc------CCHHHHHHHHHHHHHHHcCCCCcHHHHHHHHHCCCHHHHHHHHhcC-CHHHHHHHHHHHHHHHHHHHH
Confidence            888766      36788999999999998753   23334444456788888888876 788999999999999876554


No 23
>1EE4_B KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=98.36  E-value=8.2e-11  Score=117.69  Aligned_cols=364  Identities=16%  Similarity=0.224  Sum_probs=221.8  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++.+...+.+.++.++..++..+..++..... ....+...++++.+...+...+ +.++..++.++..++.........
T Consensus         3 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~   82 (423)
T 1EE4_B            3 LPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKV   82 (423)
T ss_dssp             HHHHHHHHTSSCHHHHHHHHHHHHHHHCCSSSCCHHHHHHTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             hHHHHHHhccccHHHHHHHHHHHHHHHhCCCCCchHHHHhcChHHHHHHHhhcCCcHHHHHHHHHHHHHHhCCCHHHHHH
Confidence            44566666777788888888888888754321 2222333456777777776543 667888899998887644333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|..++...                ++++
T Consensus        83 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~  145 (423)
T 1EE4_B           83 VVDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN----------------KPSL  145 (423)
T ss_dssp             HHHTTHHHHHHHHHH-HSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSC----------------CHHH
T ss_pred             HHhCChHHHHHHHHh-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcC----------------CHHH
Confidence            333456777777776 5677888899999998886532 2223333 6667776666421                2344


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      -..+..++..-...                     ...........+++..|...+..      .+......+...|.++
T Consensus       146 ~~~a~~~l~~l~~~---------------------~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l  198 (423)
T 1EE4_B          146 IRTATWTLSNLCRG---------------------KKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACWAISYL  198 (423)
T ss_dssp             HHHHHHHHHHHHCC---------------------SSSCCCHHHHGGGHHHHHHHTTC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHcC---------------------CCCCCChHHHhhHHHHHHHHHHc------CCHHHHHHHHHHHHHH
Confidence            44444443321100                     00000111122334433333221      1111112222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...                                                  +......+.+.++++.+..++. +.++
T Consensus       199 ~~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~-~~~~  227 (423)
T 1EE4_B          199 SDG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS-HEST  227 (423)
T ss_dssp             HSS--------------------------------------------------CHHHHHHHHHTTHHHHHHHHTT-CSCH
T ss_pred             hcC--------------------------------------------------CHHHHHHHHhcCHHHHHHHHhc-CCCc
Confidence            110                                                  0001112234567778888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++++.+
T Consensus       228 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l  302 (423)
T 1EE4_B          228 LVQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDANLIPPL  302 (423)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHH
T ss_pred             chhHHHHHHHHHHHhCChH-----HHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHH
Confidence            8888999999998865332     122333457888888888888888999999999999875 222 334455677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQ---PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s---~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      ..++.+      .++.++..++.+|.+++...   +.....+.+.++++.+..++.+. ++.++..++.+|.+++...+.
T Consensus       303 ~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~~~  375 (423)
T 1EE4_B          303 VKLLEV------AEDKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENILKMGEA  375 (423)
T ss_dssp             HHHHHH------SCHHHHHHHHHHHHHHHGGGGTCTHHHHHHHHTTCHHHHHHGGGSS-CHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHhc------CCHHHHHHHHHHHHHHHcCCCCcHHHHHHHHHCCCHHHHHHHHhcC-CHHHHHHHHHHHHHHHHHHHH
Confidence            888766      36788999999999998753   23334444456788888888876 788999999999999876554


No 24
>4EV8_A Catenin beta-1; mouse catenin, CELL ADHESION; HET: URE; 1.9A {Mus musculus}
Probab=98.34  E-value=9.8e-11  Score=121.45  Aligned_cols=382  Identities=19%  Similarity=0.227  Sum_probs=226.5  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++.........+
T Consensus       103 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  182 (538)
T 4EV8_A          103 GIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLII  182 (538)
T ss_pred             cHHHHHHHhCCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45556666666677888889999988876543333333345677788888877778888999999998886444333334


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+....+..++..++.++..+.........+.. ++++.+..++...                ++++..
T Consensus       183 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  246 (538)
T 4EV8_A          183 LASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLVQ  246 (538)
T ss_pred             HHCChHHHHHHHHcCCCCHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhcCC----------------CHHHHH
Confidence            44457777777776333567788888888888765444333433 6667777666432                233333


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-..                     .......+   .+.+..+...+..      .+..-...+...|.++..
T Consensus       247 ~a~~~l~~l~~---------------------~~~~~~~~---~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~  296 (538)
T 4EV8_A          247 NCLWTLRNLSD---------------------AATKQEGM---EGLLGTLVQLLGS------DDINVVTCAAGILSNLTC  296 (538)
T ss_pred             HHHHHHHHHHc---------------------CCCchHHH---cCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHc
Confidence            33333322110                     00000001   2333333333321      111112222222333221


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKDA  563 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~e  563 (747)
                      .-                                                  ......+.+.++++.++..+.. ..++.
T Consensus       297 ~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~~  326 (538)
T 4EV8_A          297 NN--------------------------------------------------YKNKMMVCQVGGIEALVRTVLRAGDRED  326 (538)
T ss_pred             CC--------------------------------------------------HHHHHHHHHCCcHHHHHHHHhcCCCCHH
Confidence            00                                                  0011122455677777776652 14566


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++.....  .......+...++++.|..++.+. +..++..++.+|.+++..... ..+...++++.+.
T Consensus       327 ~~~~a~~~l~~l~~~~~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~  404 (538)
T 4EV8_A          327 ITEPAICALRHLTSRHQE--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLV  404 (538)
T ss_pred             HHHHHHHHHHHHHcCCCC--hHHHHHHHHHCCHHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHH
Confidence            778899999998865331  000012223457788888888765 678889999999999876433 3344556778888


Q NP_000290.2     642 RLLTSHTGNT----------------SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       642 ~LL~s~s~~~----------------~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .++.......                ...+.++..++.+|.+++.. ......+...++++.++.++.+. ++.++..++
T Consensus       405 ~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~  482 (538)
T 4EV8_A          405 QLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARD-VHNRIVIRGLNTIPLFVQLLYSP-IENIQRVAA  482 (538)
T ss_pred             HHHcCCCcchhhhhccCchHHHHHhcCCCHHHHHHHHHHHHHHhCC-cchhHHHHHcChHHHHHHHhcCC-CHHHHHHHH
Confidence            7776521000                00156677899999999875 33344445556788888888876 788999999


Q NP_000290.2     706 LLLSDMWSSKELQGVLRQQGFD  727 (747)
Q Consensus       706 ~aLsnL~~~~~~~~~~~~~~~~  727 (747)
                      .+|.+++...+....+.+.|+-
T Consensus       483 ~~l~~l~~~~~~~~~~~~~~~~  504 (538)
T 4EV8_A          483 GVLCELAQDKEAAEAIEAEGAT  504 (538)
T ss_pred             HHHHHHHcCHHHHHHHHHCCcH
Confidence            9999999877665555544443


No 25
>4RXH_B Importin subunit alpha, Large T; ARM repeat, NLS, nuclear import; 1.7553A {Neurospora crassa}
Probab=98.34  E-value=1.1e-10  Score=121.65  Aligned_cols=365  Identities=17%  Similarity=0.175  Sum_probs=215.9  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.++.++..++.++..++..........
T Consensus        72 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~  151 (495)
T 4RXH_B           72 VVGRFVEFLRSPHTLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLGSPEPDVREQAVWALGNIAGDSPQCRDYV  151 (495)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHhCCChHHHHHHHhCChHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCHHHHHHH
Confidence            45566666666777888889999988876543333333345677788888887778889999999998886533333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEE-LIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~-Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+....++.++..++.++..++........ ... ++++.+..++..+                ++++-
T Consensus       152 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  215 (495)
T 4RXH_B          152 LSCGALRPLLTLLGDSRKLSMLRNATWTLSNFCRGKTPQPDWNTIAPALPVLAKLVYSL----------------DDEVL  215 (495)
T ss_dssp             HHTTCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCTTCCCHHHHTTHHHHHHHHTTCS----------------SHHHH
T ss_pred             HhCCcHHHHHHHhccccCHHHHHHHHHHHHHHhCCCCCCCcHHhhcCHHHHHHHHhhCC----------------CHHHH
Confidence            33456777777775333567888889999988875422211 112 5666666666431                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     .........---.+++..|...++.      .+..-...+...|.++.
T Consensus       216 ~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  268 (495)
T 4RXH_B          216 IDACWAISYLS---------------------DGSNDKIQAVIEAGIPRRLVELLMH------ASTSVQTPALRSVGNIV  268 (495)
T ss_dssp             HHHHHHHHHHT---------------------SSCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHh---------------------cCCHHHHHHHHHCChHHHHHHHHhc------CCccHHHHHHHHHHHHh
Confidence            33333332110                     0000000000011344444443321      01111122222222222


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..-                                                  ......+.+.++++.++.++. +.++.
T Consensus       269 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~~  297 (495)
T 4RXH_B          269 TGD--------------------------------------------------DVQTQVIINCGALPCLLSLLS-SNKDG  297 (495)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSCHH
T ss_pred             cCC--------------------------------------------------HHHHHHHHhCCHHHHHHHHHh-CCCHH
Confidence            100                                                  001112234567778888887 46778


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP----LL-HRVMGNQVFP  638 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~----e~-~~ll~~giI~  638 (747)
                      ++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++...    .. ..+...++++
T Consensus       298 v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~  372 (495)
T 4RXH_B          298 IRKEACWTISNITAGNSA-----QIQSVIDANIIPPLIHLLSHADLKTRKEACWAISNATSGGLQKPDQIRYLVAQGCIK  372 (495)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHTTTTTTTCTHHHHHHHHTTCHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHhcCCCCHHHHHHHHHCCCHH
Confidence            888899999998764332     1223344578888888888778888889999999988752    11 2233446777


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL--------------AKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~--------------~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .+..++.+      .++.++..++.+|.+++......              ...+.+.++++.|..++.+. ++.++..+
T Consensus       373 ~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a  445 (495)
T 4RXH_B          373 PLCDLLAC------PDNKIIQVALDGLENILKVGELDKNAAGDGPDSINRYALFIEECGGMEKIHDCQTNA-NEEIYMKA  445 (495)
T ss_dssp             HHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHHHHTC-----CCCHHHHHHHHTTHHHHHHHGGGCC-SSTTHHHH
T ss_pred             HHHHHhhC------CCHHHHHHHHHHHHHHHHHhhHccccCCCCCchHHHHHHHHHHccchHHHHHhhhcC-CHHHHHHH
Confidence            77777766      36778888999999888753211              22333455677788888766 78899999


Q NP_000290.2     705 RLLLSDMWSSKE  716 (747)
Q Consensus       705 L~aLsnL~~~~~  716 (747)
                      +.+|.+++...+
T Consensus       446 ~~~l~~l~~~~~  457 (495)
T 4RXH_B          446 YNIIEKYFSDED  457 (495)
T ss_dssp             HHHHHHHCC---
T ss_pred             HHHHHHhcCccc
Confidence            999999886544


No 26
>4BQK_A IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER; TRANSPORT PROTEIN, HYDROLASE, NUCLEAR LOCALIZATION; HET: PEG; 1.997A {ORYZA SATIVA}
Probab=98.32  E-value=1.2e-10  Score=118.46  Aligned_cols=366  Identities=17%  Similarity=0.164  Sum_probs=217.0  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.++..++.........+...++++.+..++.+.+..++..++.++..++.........
T Consensus        46 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  125 (456)
T 4BQK_A           46 VVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDL  125 (456)
T ss_dssp             CHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhccCcCHHHHHHHHHHHHHHhcCCHhHHHHHHhccHHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCHHHHHH
Confidence            4455566665543 778888899998887554443333444567778888887777888899999999887653333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+.+..++..+....++.++..++.++..++........... ++++.|..++...                ++++-
T Consensus       126 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~  189 (456)
T 4BQK_A          126 VLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQTRPALPALARLIHSN----------------DEEVL  189 (456)
T ss_dssp             HHHTTCHHHHHHTCCTTCCHHHHHHHHHHHHHHHCSSSCCCHHHHTTHHHHHHHHTTCC----------------CHHHH
T ss_pred             HHHCCcHHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHhcCC----------------CHHHH
Confidence            333455666666665334567888888888888775433222222 5666666666431                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..      ..+              ..++.. .-.+++..|...+..      .+..-...+...|.++.
T Consensus       190 ~~a~~~l~~l~~------~~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  242 (456)
T 4BQK_A          190 TDACWALSYLSD------GTN--------------DKIQAV-IEAGVCPRLVELLLH------PSPSVLIPALRTVGNIV  242 (456)
T ss_dssp             HHHHHHHHHHTS------SSH--------------HHHHHH-HHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhc------CCh--------------HHHHHH-HHCChHHHHHHHHhC------CCHHHHHHHHHHHHHHH
Confidence            333333322110      000              000000 012334444333321      11111222222222222


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..-                                                  ......+.+.++++.++.++....++.
T Consensus       243 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  272 (456)
T 4BQK_A          243 TGD--------------------------------------------------DAQTQCIIDHQALPCLLSLLTQNLKKS  272 (456)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHTTTHHHHHHHHHHSCCCHH
T ss_pred             cCC--------------------------------------------------HHHHHHHHHCChHHHHHHHHHcCCCHH
Confidence            100                                                  000112244567888888887322677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++..  ... ..+...++++.+
T Consensus       273 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  347 (456)
T 4BQK_A          273 IKKEACWTISNITAGNKD-----QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPL  347 (456)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHHTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHHhcCCHH-----HHHHHHHCCcHHHHHHHhhcCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCCHHHH
Confidence            888999999999865332     233334567888899999888888999999999999875  222 233344677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-----------AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLS  709 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-----------~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLs  709 (747)
                      ..++.+      .++.++..++.+|.+++...+..           ...+.+.+.++.+..++.+. ++.++..++.+|.
T Consensus       348 ~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~l~  420 (456)
T 4BQK_A          348 CDLLIC------PDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSHD-NNEIYEKAVKILE  420 (456)
T ss_dssp             HHGGGS------SCHHHHHHHHHHHHHHHHHHHHHHHHTTCSCCHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHH
T ss_pred             HHHhhC------CChHHHHHHHHHHHHHHHHhhhchhccCCCCCHHHHHHHHcchHHHHHHHHcCC-CHHHHHHHHHHHH
Confidence            888776      36788899999999998753321           11122245677788888766 7889999999999


Q NP_000290.2     710 DMWSSKE  716 (747)
Q Consensus       710 nL~~~~~  716 (747)
                      +++...+
T Consensus       421 ~l~~~~~  427 (456)
T 4BQK_A          421 AYWMDEE  427 (456)
T ss_dssp             HHCC---
T ss_pred             HHhcCcc
Confidence            9887544


No 27
>6BW9_A Importin subunit alpha-3, Protein W; Complex, Hendra virus, Importin, Karyopherin; 1.6A {Homo sapiens}
Probab=98.31  E-value=1.3e-10  Score=118.46  Aligned_cols=366  Identities=17%  Similarity=0.199  Sum_probs=218.4  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+. ..++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++.........
T Consensus        53 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  132 (459)
T 6BW9_A           53 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  132 (459)
T ss_dssp             HHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHhhCCHHHHHHHHhcCCChHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4555666665 456778888899998887654433333344567778888887777888999999999887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEEL-I-ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~L-v-egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....+..++..++.++..++......... . .++++.+..++..                .++++
T Consensus       133 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~v  196 (459)
T 6BW9_A          133 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHH----------------TDVNI  196 (459)
T ss_dssp             HHHTTCHHHHHHTCSTTSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTC----------------CCHHH
T ss_pred             HHHCCcHHHHHhccCCCCCHHHHHHHHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHhc----------------CCHHH
Confidence            3334566777777653345567888888888887643321111 1 1566666666543                13344


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-...      .+              ...... -..+++..|...++.      .+..-...++..|.++
T Consensus       197 ~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l  249 (459)
T 6BW9_A          197 LVDTVWALSYLTDA------GN--------------EQIQMV-IDSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  249 (459)
T ss_dssp             HHHHHHHHHHHHTS------CH--------------HHHHHH-HHTTCHHHHGGGGGC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhhc------Ch--------------HHHHHH-HhCChHHHHHHHcCC------CCHHHHHHHHHHHHHH
Confidence            44444333221100      00              000000 012334444333321      1111122223333333


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ....+                                                  .....+.+.++++.++.++. +.++
T Consensus       250 ~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~~~  278 (459)
T 6BW9_A          250 VTGTD--------------------------------------------------EQTQVVLNCDALSHFPALLT-HPKE  278 (459)
T ss_dssp             TTSCH--------------------------------------------------HHHHHHHTTTGGGGCHHHHT-CSCH
T ss_pred             HcCCH--------------------------------------------------HHHHHHhcccchhcHHHHhh-CCCH
Confidence            21100                                                  00111234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ......++++.
T Consensus       279 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  353 (459)
T 6BW9_A          279 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  353 (459)
T ss_dssp             HHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHH
T ss_pred             HHHHHHHHHHHHHcCCCHH-----HHHHHHHCCHHHHHHHHHHhCCHHHHHHHHHHHHHHHHhCCHHHHHHHHHCCcHHH
Confidence            8888999999999865332     223334557888888888888888999999999999864 2 21 23334467788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      +..++.+      .++.++..++.+|.+++...+...    ..+...++++.+..++.+. ++.++..++.+|.+++...
T Consensus       354 l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  426 (459)
T 6BW9_A          354 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQFFSSD  426 (459)
T ss_dssp             HHGGGGC------SCHHHHHHHHHHHHHHHHHCTTTHHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHHHHSCC-
T ss_pred             HHHhcCC------CCHHHHHHHHHHHHHHHHHhHhhHHHHHHHHHHcCHHHHHHHHhcCC-CHHHHHHHHHHHHHHcCCC
Confidence            8888776      367888999999999987533221    1233346778888888766 7889999999999998766


Q NP_000290.2     716 EL  717 (747)
Q Consensus       716 ~~  717 (747)
                      +.
T Consensus       427 ~~  428 (459)
T 6BW9_A          427 DI  428 (459)
T ss_dssp             --
T ss_pred             CC
Confidence            54


No 28
>1WA5_B GTP-BINDING NUCLEAR PROTEIN RAN, IMPORTIN; NUCLEAR TRANSPORT-COMPLEX, NUCLEAR TRANSPORT, EXPORTIN; HET: GTP; 2.0A {CANIS FAMILIARIS} SCOP: a.118.1.1
Probab=98.27  E-value=1.9e-10  Score=121.37  Aligned_cols=134  Identities=13%  Similarity=0.098  Sum_probs=85.4  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++.+++...+.....+...++++.+..++.+.+..++..++.++..++.........
T Consensus       173 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  252 (530)
T 1WA5_B          173 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  252 (530)
T ss_dssp             TCHHHHHHHHHHCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSCCHHHHHHHHHHHHHHHCCSSSCCCH
T ss_pred             ChHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCCCCCCH
Confidence            34556666676777888899999999988654433334444567778888887777888888999998887644222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRV  379 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL  379 (747)
                      ....++++.+..++. ..++.++..++.++..++.... ....+.. ++++.|+.++
T Consensus       253 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l  308 (530)
T 1WA5_B          253 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELL  308 (530)
T ss_dssp             HHHGGGHHHHHHHTT-CCCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTCHHHHHHGG
T ss_pred             HHHhhHHHHHHHHHh-cCCHHHHHHHHHHHHHHcCCCHHHHHHHHhCCHHHHHHHHh
Confidence            223456666777765 4566777778888887776422 2222222 4455555544


No 29
>5XGC_A Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF, ONCOPROTEIN; 2.1A {Homo sapiens}
Probab=98.27  E-value=2e-10  Score=117.66  Aligned_cols=409  Identities=17%  Similarity=0.214  Sum_probs=224.4  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS--PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s--~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+..  .++.++..++.++..++.... ...
T Consensus        35 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~-~~~  113 (503)
T 5XGC_A           35 LISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLGIHCQNAALTEMCLVAFGNLAELES-SKE  113 (503)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHSCCCSHHHHHHHHHTTHHHHHHHHHHHTTTCHHHHHHHHHHHHHHTTSHH-HHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCchHHHHHHHCChHHHHHHHHhccCCCHHHHHHHHHHHHHHHccHH-HHH
Confidence            55666777777778889999999999887543333344445677788888776  467888889999988876532 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      .+...++++.+...+....++.++..++.++..++........+.. ++++.++.++.......        + ....+.
T Consensus       114 ~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~--------~-~~~~~~  184 (503)
T 5XGC_A          114 QFASTNIAEELVKLFKKQIEHDKREMIFEVLAPLAENDAIKLQLVEAGLVECLLEIVQQKVDSD--------K-EDDITE  184 (503)
T ss_dssp             HHTTTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSHHHHHHHHHTTHHHHHHHHHHHHTTCC--------C-HHHHHH
T ss_pred             HHhcCCHHHHHHHHHHhcCChhHHHHHHHHHHHHHcCHHHHHHHHHCCHHHHHHHHHHhcCCCC--------C-HHHHHH
Confidence            2334466777777776222677888899999998876444444444 67777777776432100        0 000000


Q NP_000290.2     403 FFNATGCLRKRL----------------GMRELLALVPQR-------ATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       403 ~~~~~~~~~~~~----------------~~~~~~~~~~~~-------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      +..+...+..-.                -+..++.+....       +...-.+++..+..+..+.. .|.++.|+..+.
T Consensus       185 l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~-~~~~~~l~~~l~  263 (503)
T 5XGC_A          185 LKTGSDLMVLLLLGDESMQKLFEGGKGSVFQRVLSWIPSNNHQLQLAGALAIANFARNDANCIHMVD-NGIVEKLMDLLD  263 (503)
T ss_dssp             HHHHHHHHHHHTTSHHHHHHHHGGGTCHHHHHHHHHTTSSCHHHHHHHHHHHHHHCSSHHHHHHHHH-TTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhCCchHHHHHhcCcccHHHHHHHHccCCCHHHHHHHHHHHHHHHCChhHHHHHHH-CCHHHHHHHHHH
Confidence            000000000000                000111110000       00000011111111110000 011222221111


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ....  .-+..-...++.+|.++.                                   ..               . ..
T Consensus       264 ~~~~--~~~~~~~~~a~~~l~~l~-----------------------------------~~---------------~-~~  290 (503)
T 5XGC_A          264 RHVE--DGNVTVQHAALSALRNLA-----------------------------------IP---------------V-IN  290 (503)
T ss_dssp             TTTT--TCCHHHHHHHHHHHHHHT-----------------------------------CS---------------H-HH
T ss_pred             hccc--cCCHHHHHHHHHHHHHhc-----------------------------------CC---------------H-HH
Confidence            1000  000000011111111111                                   00               0 01


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-DVVRSGASL  618 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-eVr~~AL~a  618 (747)
                      ...+.+.++++.|..++. +.++.++..++.+|.+++...+.   . ........++++.+..++.+.+. .++..++++
T Consensus       291 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~---~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~  365 (503)
T 5XGC_A          291 KAKMLSAGVTEAVLKFLK-SEMPPVQFKLLGTLRMLIDAQAE---A-AEQLGKNVKLVERLVEWCEAKDHAGVMGESNRL  365 (503)
T ss_dssp             HHHHHHHTHHHHHHTTTT-CCCHHHHHHHHHHHHHHTTTCHH---H-HHHHHTCHHHHHHHHHHHTCTTCHHHHHHHHHH
T ss_pred             HHHHHHcCHHHHHHHHHc-CCCHHHHHHHHHHHHHHHccCHH---H-HHHHccccchHHHHHHHHccCCccchHHHHHHH
Confidence            122345678888888888 46778888999999999875332   0 11221235678888888877665 888999999


Q NP_000290.2     619 LSNMSRHPL---L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       619 LsnLa~~~e---~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~  693 (747)
                      |.+++....   . ..+...++++.+..++.+      .++.++..++.+|.+++...+ .....+...++++.+...+.
T Consensus       366 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  439 (503)
T 5XGC_A          366 LSALIRHSKSKDVIKTIVQSGGIKHLVTMATS------EHVIMQNEALVALALIAALELGTAEKDLESAKLVQILHRLLA  439 (503)
T ss_dssp             HHHHHHHHCCHHHHHHHHHHTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTHHHHHHHC--
T ss_pred             HHHHHHHccChhHHHHHHhcChHHHHHHHhcC------CCHHHHHHHHHHHHHHHhCCCCcHHHHHHhccHHHHHHHHHh
Confidence            999976522   2 233455677888888876      367889999999999987542 22333444457888888887


Q NP_000290.2     694 SS-ASPKAAEAARLLLSDMWSSKELQGVLRQQGFDRN  729 (747)
Q Consensus       694 s~-~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~~~~~  729 (747)
                      .. .++.++..++.+|.+++...+....+...|+..-
T Consensus       440 ~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  476 (503)
T 5XGC_A          440 DERSAPEIKYNSMVLICALMGSECLHKEVQDLAFLDV  476 (503)
T ss_dssp             -----CGGGGHHHHHHHHHTTCSSCCCSGGGTHHHHH
T ss_pred             CCCCcHHHHHHHHHHHHHHhCCHHHHHHHHHhcHHHH
Confidence            32 1578899999999999988776666655555443


No 30
>4BPL_A IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS; TRANSPORT PROTEIN, NUCLEAR IMPORT, NUCLEAR; 2.3A {ORYZA SATIVA}
Probab=98.24  E-value=2.4e-10  Score=115.88  Aligned_cols=367  Identities=17%  Similarity=0.164  Sum_probs=216.2  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+...+ +.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus        44 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  123 (454)
T 4BPL_A           44 VVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDL  123 (454)
T ss_dssp             CHHHHHHHHSCTTCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             cHHHHHHHhccCcCHHHHHHHHHHHHHHhcCChhhhHHHhhccHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4455566665543 778888889998887544433333444567778888887777888999999999887653333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+.+..++..+....++.++..++.++..++........... ++++.|..++..                -++++.
T Consensus       124 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~~  187 (454)
T 4BPL_A          124 VLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQTRPALPALARLIHS----------------NDEEVL  187 (454)
T ss_dssp             HHHTTCHHHHHHTCSTTCCHHHHHHHHHHHHHHHCSSSCCCHHHHTTHHHHHHHHTTC----------------CCHHHH
T ss_pred             HHHCCcHHHHHHHHccCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHhC----------------CCHHHH
Confidence            333455666666665334567888888888888765433222222 566666666542                123444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-...      .+              ..++.. -..+++..|...++.      .+..-...+...|.++.
T Consensus       188 ~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  240 (454)
T 4BPL_A          188 TDACWALSYLSDG------TN--------------DKIQAV-IEAGVCPRLVELLLH------PSPSVLIPALRTVGNIV  240 (454)
T ss_dssp             HHHHHHHHHHTSS------CH--------------HHHHHH-HHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhcC------Ch--------------HHHHHH-HHCCcHHHHHHHhhC------CChHHHHHHHHHHHHHh
Confidence            4444333221100      00              000000 012334444333321      01111122222222221


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..                                                  +......+.+.++++.++.++....++.
T Consensus       241 ~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~~~~~~~  270 (454)
T 4BPL_A          241 TG--------------------------------------------------DDAQTQCIIDHQALPCLLSLLTQNLKKS  270 (454)
T ss_dssp             TS--------------------------------------------------CHHHHHHHHTTTHHHHHHHHHHSSCCHH
T ss_pred             cC--------------------------------------------------CHHHHHHHHHCChHHHHHHHHHhcCCHH
Confidence            10                                                  0001112234567888888887322677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++..  ... ..+...++++.+
T Consensus       271 ~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  345 (454)
T 4BPL_A          271 IKKEACWTISNITAGNKD-----QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPL  345 (454)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHHTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHHhcCCHH-----HHHHHHhCCcHHHHHHHhhcCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCCHHHH
Confidence            888999999999865332     233334567888899999888888999999999999875  222 233444677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA-----------KQYFSSSMLNNIINLCRSSASPKAAEAARLLLS  709 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~-----------~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLs  709 (747)
                      ..++.+      .++.++..++.+|.+++.......           ..+.+.+.++.+..++.+. ++.++..++.+|.
T Consensus       346 ~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~  418 (454)
T 4BPL_A          346 CDLLIC------PDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSHD-NNEIYEKAVKILE  418 (454)
T ss_dssp             HHTTTC------SCHHHHHHHHHHHHHHHHHHHHHHHHHTCSSCHHHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHHH
T ss_pred             HHHhcC------CChHHHHHHHHHHHHHHHHhhhchhcccCCCCHHHHHHHHcccHHHHHHHHcCC-CHHHHHHHHHHHH
Confidence            888776      367888899999999987532211           1112245677788888766 7889999999999


Q NP_000290.2     710 DMWSSKEL  717 (747)
Q Consensus       710 nL~~~~~~  717 (747)
                      .+....+.
T Consensus       419 ~l~~~~~~  426 (454)
T 4BPL_A          419 AYWMDEED  426 (454)
T ss_dssp             HHCC----
T ss_pred             HHhcCccc
Confidence            99876544


No 31
>4B8J_A IMPORTIN SUBUNIT ALPHA-1A; TRANSPORT PROTEIN, NUCLEAR LOCALIZATION SIGNAL; 2.001A {ORYZA SATIVA JAPONICA GROUP}
Probab=98.24  E-value=2.6e-10  Score=119.98  Aligned_cols=367  Identities=17%  Similarity=0.160  Sum_probs=217.7  Template_Neff=12.400

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.+|..++.........+...++++.+..++.+.+..++..++.+|..++.........
T Consensus       118 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  197 (528)
T 4B8J_A          118 VVPRFVQFLTREDFPQLQFEAAWALTNIASGTSENTKVVIDHGAVPIFVKLLGSSSDDVREQAVWALGNVAGDSPKCRDL  197 (528)
T ss_dssp             CHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHHTCHHHHHH
T ss_pred             cHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCChHHHHHHHhCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4555666665544 778888999998887544433333444557778888887777888899999999887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+++..++..+....++.++..++.++..++........... ++++.|..++..                .++++.
T Consensus       198 ~~~~~~l~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~v~  261 (528)
T 4B8J_A          198 VLANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQPSFEQTRPALPALARLIHS----------------NDEEVL  261 (528)
T ss_dssp             HHHTTCHHHHHHTCCTTCCHHHHHHHHHHHHHHHCSSSCCCHHHHTTHHHHHHHHTTC----------------CCHHHH
T ss_pred             HHHCCcHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCCCCCHHHHhhHHHHHHHHhcC----------------CCHHHH
Confidence            333455666666664334567888888999888875433222222 566666666643                133444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|..-..      ..+              ...+.+ ...++++.|+..++.      .+..-...+...|.++.
T Consensus       262 ~~a~~~l~~l~~------~~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  314 (528)
T 4B8J_A          262 TDACWALSYLSD------GTN--------------DKIQAV-IEAGVCPRLVELLLH------PSPSVLIPALRTVGNIV  314 (528)
T ss_dssp             HHHHHHHHHHTS------SCH--------------HHHHHH-HHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhc------CCh--------------HHHHHH-HHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHH
Confidence            444443322110      000              000000 012344444433321      01111122222222222


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ..-                                                  ......+.+.++++.|+.++....++.
T Consensus       315 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  344 (528)
T 4B8J_A          315 TGD--------------------------------------------------DAQTQCIIDHQALPCLLSLLTQNLKKS  344 (528)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHTTTHHHHHHHHHHSCCCHH
T ss_pred             cCC--------------------------------------------------HHHHHHHHHCChHHHHHHHHhcCCCHH
Confidence            100                                                  001112245567888888887322677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...++++.|
T Consensus       345 v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  419 (528)
T 4B8J_A          345 IKKEACWTISNITAGNKD-----QIQAVINAGIIGPLVNLLQTAEFDIKKEAAWAISNATSGGSHDQIKYLVSEGCIKPL  419 (528)
T ss_dssp             HHHHHHHHHHHHHTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCCchHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCCHHHH
Confidence            888999999999865332     233334567888999999888888999999999999875 2 22 233344677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-----------AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLS  709 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-----------~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLs  709 (747)
                      ..++.+      .++.++..++.+|.+++......           ...+.+.++++.|..++.+. ++.++..|+.+|.
T Consensus       420 ~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~l~  492 (528)
T 4B8J_A          420 CDLLIC------PDIRIVTVCLEGLENILKVGETDKTLAAGDVNVFSQMIDEAEGLEKIENLQSHD-NNEIYEKAVKILE  492 (528)
T ss_dssp             HHGGGC------SCHHHHHHHHHHHHHHHHHHHHHHHHHTCSCCHHHHHHHHTTHHHHHHHGGGCS-SHHHHHHHHHHHH
T ss_pred             HHHccC------CCHHHHHHHHHHHHHHHHHhHHcHhhcCCCCcHHHHHHHHcCHHHHHHHHhcCC-CHHHHHHHHHHHH
Confidence            888776      36788899999999998753221           11122345677788888766 7889999999999


Q NP_000290.2     710 DMWSSKEL  717 (747)
Q Consensus       710 nL~~~~~~  717 (747)
                      +++...+.
T Consensus       493 ~l~~~~~~  500 (528)
T 4B8J_A          493 AYWMDEED  500 (528)
T ss_dssp             HHCC----
T ss_pred             Hhcccccc
Confidence            98875544


No 32
>5T94_B Guanine nucleotide exchange factor SRM1; Nuclear Import, Importin alpha, RCC1; 2.631A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=98.23  E-value=2.9e-10  Score=120.53  Aligned_cols=364  Identities=15%  Similarity=0.171  Sum_probs=219.0  Template_Neff=12.200

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.++..+.+.+ +.++..++.+|..++.........+...++++.+...+.+.++.++..++.++..++.........
T Consensus       131 ~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  210 (542)
T 5T94_B          131 VVPRLVEFMRENQPEMLQLEAAWALTNIASGTSAQTKVVVDADAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDY  210 (542)
T ss_dssp             CHHHHHHTTSSSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCHHHHHH
T ss_pred             hHHHHHHHhhcCCCHHHHHHHHHHHHHHHcCChHHHHHHhcCChHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHH
Confidence            4555666665443 677888899998887654333333334567777888887777888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+..++. ..++.++..++.+|..++.... ....... ++++.|+.++..                .++++
T Consensus       211 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~  273 (542)
T 5T94_B          211 VLQCNAMEPILGLFN-SNKPSLIRTATWTLSNLCRGKKPQPDWSVVSQALPTLAKLIYS----------------MDTET  273 (542)
T ss_dssp             HHHTTCHHHHHHGGG-CCCHHHHHHHHHHHHHHSCCSTTCCCHHHHGGGHHHHHHHTTC----------------CCHHH
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCCCCCCHHHHhcHHHHHHHHHhc----------------CCHHH
Confidence            344467777777776 5567788889999998887542 2222222 566777766642                12334


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-...      -+              ...+.+. -.+++..|...++.      .+..-...+...|.++
T Consensus       274 ~~~a~~~L~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l  326 (542)
T 5T94_B          274 LVDACWAISYLSDG------PQ--------------EAIQAVI-DVRIPKRLVELLSH------ESTLVQTPALRAVGNI  326 (542)
T ss_dssp             HHHHHHHHHHHSSS------SH--------------HHHHHHH-HTTCHHHHHHTTSC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHcCC------CH--------------HHHHHHH-hCCHHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            33333333221100      00              0000000 01233333322221      1111112222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.|+.++. +.++
T Consensus       327 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  355 (542)
T 5T94_B          327 VTGN--------------------------------------------------DLQTQVVINAGVLPALRLLLS-SPKE  355 (542)
T ss_dssp             TTSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSSH
T ss_pred             HcCC--------------------------------------------------HHHHHHHHHCChHHHHHHHhh-CCCH
Confidence            2100                                                  001111234567888888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL----L-HRVMGNQVF  637 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e----~-~~ll~~giI  637 (747)
                      .++..++++|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++....    . ..+...+++
T Consensus       356 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  430 (542)
T 5T94_B          356 NIKKEACWTISNITAGNTE-----QIQAVIDANLIPPLVKLLEVAEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCI  430 (542)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHGGGTTCTHHHHHHHHTTCH
T ss_pred             HHHHHHHHHHHHHhCCCHH-----HHHHHHHCCchHHHHHHHHcCCHHHHHHHHHHHHHHHcCCCCCHHHHHHHHHCCCH
Confidence            8888999999999875332     23333456788888888888888899999999999987621    1 223345678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-----------LAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-----------~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      +.|..++.+      .++.++..++.+|.+++...+.           ....+.+.++++.|..++.+. ++.++..|+.
T Consensus       431 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~ll~~~-~~~v~~~a~~  503 (542)
T 5T94_B          431 KPLCDLLEI------ADNRIIEVTLDALENILKMGEADKEARGLNINENADFIEKAGGMEKIFNCQQNE-NDKIYEKAYK  503 (542)
T ss_dssp             HHHHHHHHH------CCHHHHHHHHHHHHHHHHHHHHHTTTTTCSSCTTTHHHHHTTCHHHHHTTSSSC-CHHHHHHHHH
T ss_pred             HHHHHHhcC------CCHHHHHHHHHHHHHHHHHHHHHHHHcCCCccHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHH
Confidence            888888876      3677888999999999875332           123344456788888888766 7889999999


Q NP_000290.2     707 LLSDMWSSKE  716 (747)
Q Consensus       707 aLsnL~~~~~  716 (747)
                      +|.+++...+
T Consensus       504 ~l~~l~~~~~  513 (542)
T 5T94_B          504 IIETYFGEEE  513 (542)
T ss_dssp             HHHHHC----
T ss_pred             HHHHHhCcCc
Confidence            9999987543


No 33
>4TNM_A Importin-alpha3 / MOS6; armadillo repeat; 2.9A {Arabidopsis thaliana}
Probab=98.21  E-value=3.2e-10  Score=119.57  Aligned_cols=369  Identities=17%  Similarity=0.184  Sum_probs=220.4  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLSSQD-EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd-~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.+ +.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus       119 ~~~~l~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  198 (531)
T 4TNM_A          119 VVPRVVKFLSRDDFPKLQFEAAWALTNIASGTSENTNVIIESGAVPIFIQLLSSASEDVREQAVWALGNVAGDSPKCRDL  198 (531)
T ss_pred             CHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCCHHHHHHHccCCCHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665544 778888889998887644333333444567778888887777888999999999887653333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+++..+...+....+..++..++.++..++........... ++++.|..++...                ++++.
T Consensus       199 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  262 (531)
T 4TNM_A          199 VLSYGAMTPLLSQFNENTKLSMLRNATWTLSNFCRGKPPPAFEQTQPALPVLERLVQSM----------------DEEVL  262 (531)
T ss_pred             HHHCCCHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCCCCcchhhhcchHHHHHHHhcCC----------------CHHHH
Confidence            333456666666664334567888888898888765433222222 5666666665431                33444


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|..-..                     .+......-.-.+++..|...+..      .+..-...+...|.++.
T Consensus       263 ~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~  315 (531)
T 4TNM_A          263 TDACWALSYLSD---------------------NSNDKIQAVIEAGVVPRLIQLLGH------SSPSVLIPALRTIGNIV  315 (531)
T ss_pred             HHHHHHHHHHhC---------------------CCHHHHHHHHHCChHHHHHHHHhC------CCHHHHHHHHHHHHHHH
Confidence            444433322110                     000000000012334444333321      11112222233333322


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                  .....+.+.++++.|+.++....++.
T Consensus       316 ~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~~~~~~~  345 (531)
T 4TNM_A          316 TGDD--------------------------------------------------LQTQMVLDQQALPCLLNLLKNNYKKS  345 (531)
T ss_pred             CCCH--------------------------------------------------HHHHHHHHCCcHHHHHHHhcCCCCHH
Confidence            1100                                                  00111234467788888887323567


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PL-L-HRVMGNQVFPEV  640 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e-~-~~ll~~giI~~L  640 (747)
                      ++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++.. .. . ..+...++++.|
T Consensus       346 v~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l  420 (531)
T 4TNM_A          346 IKKEACWTISNITAGNAD-----QIQAVIDAGIIQSLVWVLQSAEFEVKKEAAWGISNATSGGTHDQIKFMVSQGCIKPL  420 (531)
T ss_pred             HHHHHHHHHHHHHCCCHH-----HHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHHCCcHHHH
Confidence            888999999999875332     233334566888888888887888999999999999875 21 2 233344677888


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQ------------PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s------------~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ..++.+      .++.++..++.+|.+++...            ......+.+.++++.|..++.+. ++.++..|+.+|
T Consensus       421 ~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~l  493 (531)
T 4TNM_A          421 CDLLTC------PDLKVVTVCLEALENILVVGEAEKNLGHTGEDNLYAQMIDEAEGLEKIENLQSHD-NNDIYDKAVKIL  493 (531)
T ss_pred             HHHccC------CCHHHHHHHHHHHHHHHhhCccchhhcCCCCcHHHHHHHHHCCcHHHHHHHhcCC-CHHHHHHHHHHH
Confidence            888776      36788899999999998531            11223334446788888888776 788999999999


Q NP_000290.2     709 SDMWSSKELQG  719 (747)
Q Consensus       709 snL~~~~~~~~  719 (747)
                      .+++...+...
T Consensus       494 ~~l~~~~~~~~  504 (531)
T 4TNM_A          494 ETFWTEDNEEE  504 (531)
T ss_pred             HHHhcCCCCcc
Confidence            99987655443


No 34
>5TBK_C Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=98.21  E-value=3.4e-10  Score=119.34  Aligned_cols=366  Identities=16%  Similarity=0.161  Sum_probs=222.2  Template_Neff=12.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.+|..++...... ...+...++++.+...+... +..++..++.++..++.......
T Consensus        71 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  150 (521)
T 5TBK_C           71 TSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT  150 (521)
T ss_dssp             CCSSTHHHHTTSSCHHHHHHHHHHHHHHHHTTTCCCTTSCTTTTHHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHH
T ss_pred             hcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHH
Confidence            35566677777777788888999998887643221 12233346677777777643 67788888999988876543333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .++
T Consensus       151 ~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~  214 (521)
T 5TBK_C          151 QAVVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS---------------IPI  214 (521)
T ss_dssp             HHHHTTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHHHCHHHHHHHHHTTCHHHHHTTCCTT---------------SCH
T ss_pred             HHHHHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhCCC---------------CCH
Confidence            33334457777777776 5567888899999999886432 2222333 6677777766532               123


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..+|..-.                     .............+++..|...+..      .+..-...+..+|.
T Consensus       215 ~~~~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~  267 (521)
T 5TBK_C          215 TFLRNVTWVMVNLC---------------------RHKDPPPPMETIQEILPALCVLIHH------TDVNILVDTVWALS  267 (521)
T ss_dssp             HHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH---------------------cCCCCCCCHHHHHHHHHHHHHHhhC------CCHHHHHHHHHHHH
Confidence            33333433332211                     0000001111122333333333221      11222223333333


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ++...-+                                                  .....+.+.++++.++.++. +.
T Consensus       268 ~l~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  296 (521)
T 5TBK_C          268 YLTDAGN--------------------------------------------------EQIQMVIDSGIVPHLVPLLS-HQ  296 (521)
T ss_dssp             HHHHHCH--------------------------------------------------HHHHHHHHTTCHHHHGGGGG-CS
T ss_pred             HHhccCh--------------------------------------------------HHHHHHHHCChHHHHHHHhc-CC
Confidence            3321100                                                  01112234567788888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++... .. ..+...++++
T Consensus       297 ~~~v~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  371 (521)
T 5TBK_C          297 EVKVQTAALRAVGNIVTGTDE-----QTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVP  371 (521)
T ss_dssp             SHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCGGGHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTCHH
T ss_pred             CHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCCHHHhHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHH
Confidence            677888899999998875332     2233344578888888888888889999999999998762 22 2334456778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .|..++.+      .++.++..++.+|.+++.... .....+.+.++++.|..++.+. ++.++..++.+|.+++...+
T Consensus       372 ~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~L~~~l~~~-~~~v~~~a~~~l~~l~~~~~  443 (521)
T 5TBK_C          372 MIIHLLDK------GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVK-DAQVVQVVLDGLSNILKMAE  443 (521)
T ss_dssp             HHHHHHHH------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHHHHGGGGSS-CHHHHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHh------CCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHhH
Confidence            88888776      367788999999999985322 2233344456788888888766 77888999999999887543


No 35
>5TBK_D Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=98.21  E-value=3.4e-10  Score=119.34  Aligned_cols=366  Identities=16%  Similarity=0.161  Sum_probs=221.8  Template_Neff=12.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESA-KQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~-~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.+|..++...... ...+...++++.+...+... +..++..++.++..++.......
T Consensus        71 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  150 (521)
T 5TBK_D           71 TSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQT  150 (521)
T ss_dssp             -CCSHHHHHTTSSCHHHHHHHHHHHHTHHHHHHSSCSHHHHHHTHHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHH
T ss_pred             hcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHH
Confidence            35566677777777788888999998887643221 12233346677777777643 67788888999988876543333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .++
T Consensus       151 ~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~  214 (521)
T 5TBK_D          151 QAVVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS---------------IPI  214 (521)
T ss_dssp             HHHHTTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHHHCHHHHHHHHHTCCHHHHHTTCCTT---------------SCH
T ss_pred             HHHHHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhCCC---------------CCH
Confidence            33334457777777776 5567888899999999886432 2222333 6677777766532               123


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..+|..-.                     .............+++..|...+..      .+..-...+..+|.
T Consensus       215 ~~~~~a~~~l~~l~---------------------~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~  267 (521)
T 5TBK_D          215 TFLRNVTWVMVNLC---------------------RHKDPPPPMETIQEILPALCVLIHH------TDVNILVDTVWALS  267 (521)
T ss_dssp             HHHHHHHHHHHHHH---------------------CCCSSCCCHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH---------------------cCCCCCCCHHHHHHHHHHHHHHhhC------CCHHHHHHHHHHHH
Confidence            33333433332211                     0000001111122333333333221      11222223333333


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ++...-+                                                  .....+.+.++++.++.++. +.
T Consensus       268 ~l~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  296 (521)
T 5TBK_D          268 YLTDAGN--------------------------------------------------EQIQMVIDSGIVPHLVPLLS-HQ  296 (521)
T ss_dssp             HHHHHCH--------------------------------------------------HHHHHHHHTTCHHHHGGGGG-CS
T ss_pred             HHhccCh--------------------------------------------------HHHHHHHHCChHHHHHHHhc-CC
Confidence            3321100                                                  01112234567788888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++... .. ..+...++++
T Consensus       297 ~~~v~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  371 (521)
T 5TBK_D          297 EVKVQTAALRAVGNIVTGTDE-----QTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLVP  371 (521)
T ss_dssp             SHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTCGGGHHHHHHCSCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTCHH
T ss_pred             CHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCCHHHhHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHH
Confidence            677888899999998875332     2233344578888888888888889999999999998762 22 2334456778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .|..++.+      .++.++..++.+|.+++.... .....+.+.++++.|..++.+. ++.++..++.+|.+++...+
T Consensus       372 ~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~L~~~l~~~-~~~v~~~a~~~l~~l~~~~~  443 (521)
T 5TBK_D          372 MIIHLLDK------GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVK-DAQVVQVVLDGLSNILKMAE  443 (521)
T ss_dssp             HHHHHHHH------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHHHHGGGGSS-CHHHHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHh------CCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHhH
Confidence            88888776      367788999999999985322 2233344456788888888766 77888999999999887543


No 36
>2Z6G_A B-catenin; Full-Length, Beta-Catenin, CELL ADHESION; 3.4A {Danio rerio}
Probab=98.14  E-value=6.4e-10  Score=126.67  Aligned_cols=381  Identities=19%  Similarity=0.217  Sum_probs=223.9  Template_Neff=10.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+..++.+.+..++..++.+|.+++.........+...++++.+..++...+..++..++.+|..++.........
T Consensus       234 ~~i~~L~~lL~~~~~~v~~~al~~L~~l~~~~~~~~~~~~~~~~~~~L~~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~  313 (780)
T 2Z6G_A          234 GGIPALVNMLGSPVDSVLFHAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLI  313 (780)
T ss_pred             CcHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34566666776667788888999998887654333333333567777888887777888889999999888644433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      +...+++..++.++....+..++..++.+|..++........+.. ++++.|..++...                ++++.
T Consensus       314 ~~~~~~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~l~~L~~~l~~~----------------~~~v~  377 (780)
T 2Z6G_A          314 ILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLV  377 (780)
T ss_pred             HHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHhCCHHHHHHHHHCCHHHHHHHHccCC----------------CHHHH
Confidence            333456777777776223567788888888888765443333333 6677777666531                23343


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|+.-..                     ......   ...+++..|...+..      .+..-...+..+|.++.
T Consensus       378 ~~al~~L~~l~~---------------------~~~~~~---~~~~~l~~L~~~l~~------~~~~v~~~a~~~L~~l~  427 (780)
T 2Z6G_A          378 QNCLWTLRNLSD---------------------AATKQE---GMEGLLGTLVQLLGS------DDINVVTCAAGILSNLT  427 (780)
T ss_pred             HHHHHHHHHHhc---------------------CCCCHH---HHcChHHHHHHHhcC------CCHHHHHHHHHHHHHHH
Confidence            344433332110                     000000   012333333333221      01111222222333322


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGK-SKKD  562 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~s-s~d~  562 (747)
                      ...                                                  ......+...++++.|+..+.. ..++
T Consensus       428 ~~~--------------------------------------------------~~~~~~~~~~~~l~~L~~~l~~~~~~~  457 (780)
T 2Z6G_A          428 CNN--------------------------------------------------YKNKMMVCQVGGIEALVRTVLRAGDRE  457 (780)
T ss_pred             cCC--------------------------------------------------HHHHHHHHHCChHHHHHHHHhcCCCCH
Confidence            110                                                  0001112345667777776652 1456


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEV  640 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~L  640 (747)
                      .++..++.+|.+++.....  .......+...++++.|+.++... ++.++..++.+|.+++..... ..+...++++.|
T Consensus       458 ~v~~~a~~~L~~l~~~~~~--~~~~~~~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~l~~L  535 (780)
T 2Z6G_A          458 DITEPAICALRHLTSRHQD--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRL  535 (780)
T ss_pred             HHHHHHHHHHHHHHcCCcc--HHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHhCChHHHH
Confidence            7788899999998865321  000112223456788888888765 577889999999999876333 233455677788


Q NP_000290.2     641 TRLLTSHTGN----------------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       641 l~LL~s~s~~----------------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      +.++......                ...+..++..++.+|.+|+.. ......+...++++.|+.++.+. ++.++..+
T Consensus       536 ~~ll~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~aL~~L~~~-~~~~~~~~~~~~l~~L~~~l~~~-~~~v~~~a  613 (780)
T 2Z6G_A          536 VQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEACTGALHILARD-IHNRIVIRGLNTIPLFVQLLYSP-IENIQRVA  613 (780)
T ss_pred             HHHhcCCCHHHHHHHHhhhhhhhhhcCCChHHHHHHHHHHHHHHhCC-hhHHHHHHhCCcHHHHHHHhcCC-CHHHHHHH
Confidence            8777652000                000234888999999999864 44444455556788888888776 78899999


Q NP_000290.2     705 RLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       705 L~aLsnL~~~~~~~~~~~~~~  725 (747)
                      +.+|.+++...+....+...|
T Consensus       614 ~~~L~~l~~~~~~~~~~~~~~  634 (780)
T 2Z6G_A          614 AGVLCELAQDKEAAEAIEAEG  634 (780)
T ss_pred             HHHHHHHhcCHHHHHHHHHCC
Confidence            999999997766554444433


No 37
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=98.13  E-value=6.1e-10  Score=114.95  Aligned_cols=326  Identities=17%  Similarity=0.189  Sum_probs=198.8  Template_Neff=13.100

Q NP_000290.2     286 LGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKE  365 (747)
Q Consensus       286 ~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~  365 (747)
                      .++++.+...+.+.+..++..++.++..++.............++++.+...+....++.++..++.++..+........
T Consensus        16 ~~~i~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~   95 (529)
T 1JDH_A           16 TRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLL   95 (529)
T ss_dssp             -CHHHHHHHHHTCSCHHHHHHHHHHHHHHHTSHHHHHHHHTCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSHHHHH
T ss_pred             HhhHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHHhCcchHHHHHHHhhCCCCHHHHHHHHHHHHHHhcCHHHHH
Confidence            45677777778777788888999999888765322211111134667777777533567788899999998876544443


Q NP_000290.2     366 ELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTM  444 (747)
Q Consensus       366 ~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  444 (747)
                      .+.. ++++.|+.++..+                ++++-..+..++..-....                    +..+...
T Consensus        96 ~~~~~~~~~~l~~~l~~~----------------~~~~~~~a~~~l~~l~~~~--------------------~~~~~~~  139 (529)
T 1JDH_A           96 AIFKSGGIPALVKMLGSP----------------VDSVLFYAITTLHNLLLHQ--------------------EGAKMAV  139 (529)
T ss_dssp             HHHHTTHHHHHHHHTTCS----------------CHHHHHHHHHHHHHHHHHC--------------------TTHHHHH
T ss_pred             HHHHcCCHHHHHHHhcCC----------------CHHHHHHHHHHHHHHHcCC--------------------cchHHHH
Confidence            4444 6777777776532                3444444444433211100                    0000100


Q NP_000290.2     445 RNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNN  524 (747)
Q Consensus       445 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  524 (747)
                       .-.++++.|...++.      -+..-...+...|.++...-                                      
T Consensus       140 -~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~--------------------------------------  174 (529)
T 1JDH_A          140 -RLAGGLQKMVALLNK------TNVKFLAITTDCLQILAYGN--------------------------------------  174 (529)
T ss_dssp             -HHHTHHHHHHHGGGC------CCHHHHHHHHHHHHHHHTTC--------------------------------------
T ss_pred             -HHcChHHHHHHHhcC------CCHHHHHHHHHHHHHHhcCC--------------------------------------
Confidence             012444544444332      12222233333333332100                                      


Q NP_000290.2     525 NYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL  604 (747)
Q Consensus       525 ~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL  604 (747)
                                  ......+.+.++++.++.++....++.++..++.+|.+++....      ....+...++++.+..++
T Consensus       175 ------------~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~------~~~~~~~~~~~~~l~~~l  236 (529)
T 1JDH_A          175 ------------QESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSS------NKPAIVEAGGMQALGLHL  236 (529)
T ss_dssp             ------------HHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTT------HHHHHHHTTHHHHHHTTT
T ss_pred             ------------HHHHHHHHHCChhHHHHHHHccCCcHHHHHHHHHHHHHHhcCCc------cHHHHHHCCHHHHHHHHc
Confidence                        01112234566788888888742366788889999999887532      133334567888899988


Q NP_000290.2     605 QSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM  684 (747)
Q Consensus       605 ~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~gi  684 (747)
                      .+.++.++..++++|.+++......... .++++.+..++.+      .++.++..++.+|.+++...+.....+...+.
T Consensus       237 ~~~~~~~~~~~~~~l~~l~~~~~~~~~~-~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~  309 (529)
T 1JDH_A          237 TDPSQRLVQNCLWTLRNLSDAATKQEGM-EGLLGTLVQLLGS------DDINVVTCAAGILSNLTCNNYKNKMMVCQVGG  309 (529)
T ss_dssp             TSSCHHHHHHHHHHHHHHHTTCTTCSCC-HHHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTH
T ss_pred             cCCCHHHHHHHHHHHHHHcchhhhHHHH-chHHHHHHHHhCC------CCHHHHHHHHHHHHHHhcCCHHHHHHHHHcCH
Confidence            8888889999999999998763221111 4566777777765      36788899999999998765555555666677


Q NP_000290.2     685 LNNIINLCRS-SASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       685 L~~Ll~LL~s-~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      ++.++..+.. ..++.++..++.+|.+++.....
T Consensus       310 ~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~  343 (529)
T 1JDH_A          310 IEALVRTVLRAGDREDITEPAICALRHLTSRHQE  343 (529)
T ss_dssp             HHHHHHHHHHHTTCHHHHHHHHHHHHHHTSSSTT
T ss_pred             HHHHHHHHHhcCCChHhHHHHHHHHHHHhcCccc
Confidence            8888876652 12577888999999998866553


No 38
>2Z6H_A Catenin beta-1; Beta-Catenin, C-terminal Domain, Activator, Cell; 2.2A {Homo sapiens}
Probab=98.12  E-value=7.3e-10  Score=121.28  Aligned_cols=378  Identities=20%  Similarity=0.248  Sum_probs=205.2  Template_Neff=11.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+...+..++..++.++..++.........+
T Consensus        99 ~i~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~  178 (644)
T 2Z6H_A           99 GIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLII  178 (644)
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666766777888899999998876543333333345677778888877778888899999998886444333334


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...+++..+...+....+..++..++.++..++........+.. ++++.|..++...                ++++..
T Consensus       179 ~~~~~~~~L~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~l~~l~~~l~~~----------------~~~~~~  242 (644)
T 2Z6H_A          179 LASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDP----------------SQRLVQ  242 (644)
T ss_pred             HHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHccChHHHHHHHHCCHHHHHHHHhcCC----------------CHHHHH
Confidence            44457777777776333567788888888888765443333333 6666676666532                111222


Q NP_000290.2     405 NATGCLRKRL-----------GMRELLALVPQ-------RATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASR  466 (747)
Q Consensus       405 ~~~~~~~~~~-----------~~~~~~~~~~~-------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  466 (747)
                      .+..+|..-.           .+..++.++..       .+...-.++...+......-.-.+.++.|...+..    ..
T Consensus       243 ~a~~~L~~l~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~l~~L~~~l~~----~~  318 (644)
T 2Z6H_A          243 NCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLR----AG  318 (644)
T ss_pred             HHHHHHHHHhcCCCCHHHHCchHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCCHHHHHHHHHhc----CC
Confidence            2222221100           01111111110       00000111111111000000112334444333221    01


Q NP_000290.2     467 CDDKSVENCMCVLHNLSYRLDAEV------------PTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEE  534 (747)
Q Consensus       467 ~~~~~~~~~~~~~~~~~~~~~~~~------------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  534 (747)
                      -+..-.+.+...|.++........            +.-.+.+... .+....+....++.+-.                
T Consensus       319 ~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~v~~~a~~~L~~l~----------------  381 (644)
T 2Z6H_A          319 DREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPP-SHWPLIKATVGLIRNLA----------------  381 (644)
T ss_pred             CCHHHHHHHHHHHHHHHcCCCCHHHHHHHHHHCCcHHHHHHHhcCC-CCHHHHHHHHHHHHHHh----------------
Confidence            123345666777777765433210            0000000000 00000011111111111                


Q NP_000290.2     535 TNPKGSGWLYHSDAIRTYLNLMGKSKK----------------------DATLEACAGALQNLTASKGLMSSGMSQLIGL  592 (747)
Q Consensus       535 ~ni~~~~~lve~G~I~~LL~LL~ss~d----------------------~eVr~~AL~aL~nLs~~s~~~s~~~~~~lli  592 (747)
                      ........+.+.++++.|+.++.. ..                      ..++..++.+|.+++.....      ...+.
T Consensus       382 ~~~~~~~~l~~~~~~~~L~~~l~~-~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~L~~l~~~~~~------~~~~~  454 (644)
T 2Z6H_A          382 LCPANHAPLREQGAIPRLVQLLVR-AHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHN------RIVIR  454 (644)
T ss_pred             cCHHHHHHHHHCCcHHHHHHHHcc-CCHHHHHHHhcCCchhhhhcCCCCHHHHHHHHHHHHHHhcCcch------HHHHH
Confidence            001112234566788888888863 32                      23777888899988865321      22334


Q NP_000290.2     593 KEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       593 e~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      ..++++.|+.++.+.++.++..++.+|.+++..... ..+...++++.|..++.+      .++.++..++.+|.+++..
T Consensus       455 ~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~L~~~l~~------~~~~v~~~a~~~L~~l~~~  528 (644)
T 2Z6H_A          455 GLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHS------RNEGVATYAAAVLFRMSED  528 (644)
T ss_pred             HCCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCHHHHHHHHHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhCC
Confidence            457888899989888889999999999999876433 233445778888888876      3678999999999999875


Q NP_000290.2     672 QP  673 (747)
Q Consensus       672 s~  673 (747)
                      .+
T Consensus       529 ~~  530 (644)
T 2Z6H_A          529 KP  530 (644)
T ss_pred             Cc
Confidence            43


No 39
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=98.11  E-value=7.7e-10  Score=121.20  Aligned_cols=342  Identities=20%  Similarity=0.251  Sum_probs=215.3  Template_Neff=11.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.+..++..++..|..++.........+...++++.+..++.+.++.++..++.++..++........
T Consensus       177 ~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~  256 (671)
T 6SA8_A          177 KKILKDLVKKLSSPNENELQNALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQ  256 (671)
T ss_dssp             HHHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHH
T ss_pred             HHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCcHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHH
Confidence            44566677777777778888899999888765433333444456778888888877888899999999988764443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      .+...+.++.+...+. +.++.++..++.++..++... .....+.. ++++.|+.++...                +++
T Consensus       257 ~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~----------------~~~  319 (671)
T 6SA8_A          257 AVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSP----------------NEQ  319 (671)
T ss_dssp             HHHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCS----------------CHH
T ss_pred             HHHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCcHHHHHHHHhChHHHHHHHhcCC----------------cHH
Confidence            3444567778888876 566788889999999888643 22233333 6777777776531                344


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN  481 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  481 (747)
                      +-..+..+|..-..      ..+              ..+..+. -.++++.|+..++..      +....+.++..|.+
T Consensus       320 v~~~a~~~L~~l~~------~~~--------------~~~~~~~-~~~~l~~l~~~l~~~------~~~~~~~a~~~L~~  372 (671)
T 6SA8_A          320 ILQEALWALSNIAS------GGN--------------EQIQAVI-DAGALPALVQLLSSP------NEQILQEALWALSN  372 (671)
T ss_dssp             HHHHHHHHHHHHTT------SCH--------------HHHHHHH-HTTHHHHHHHHTTCS------CHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhc------CCc--------------HHHHHHH-hcChHHHHHHHhcCC------CHHHHHHHHHHHHH
Confidence            44444433322110      000              0011111 123444554444321      22333344444444


Q NP_000290.2     482 LSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK  561 (747)
Q Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d  561 (747)
                      +...-                                                  ......+.+.++++.|+.++. ..+
T Consensus       373 l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~  401 (671)
T 6SA8_A          373 IASGG--------------------------------------------------NEQIQAVIDAGALPALVQLLS-SPN  401 (671)
T ss_dssp             HTTSC--------------------------------------------------HHHHHHHHHTTHHHHHHHGGG-CSC
T ss_pred             HHcCC--------------------------------------------------cHHHHHHHHcCcHHHHHHHhc-CCC
Confidence            43200                                                  001112245567888888887 467


Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL-L-HRVMGNQVFPE  639 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-~-~~ll~~giI~~  639 (747)
                      +.++..++.+|.+++.....     ....+.+.++++.|+.++.+.++.++..++.+|.+++.... . ..+...++++.
T Consensus       402 ~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~  476 (671)
T 6SA8_A          402 EQILQEALWALSNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPA  476 (671)
T ss_dssp             HHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHH
T ss_pred             HHHHHHHHHHHHhhcCCCHH-----HHHHHHhcCcHHHHHHHcCCCCHHHHHHHHHHHHHHHcCChHHHHHHHhcCcHHH
Confidence            78888999999999875332     23333456788899999988888999999999999996632 2 23345667888


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINL  691 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~L  691 (747)
                      |..++.+      .++.++..++.+|.+|+...+.....+...+.++.++..
T Consensus       477 l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~ll~~  522 (671)
T 6SA8_A          477 LVQLLSS------PNEQIQDEAEKTLLNIANGSEEQQKAVYDAGALKYLLII  522 (671)
T ss_dssp             HHHHTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHH
T ss_pred             HHHHhhC------CCHHHHHHHHHHHHHHHcCCHHHHHHHhcccHHHHHHHH
Confidence            8888876      367889999999999987655555555555555555544


No 40
>4RXH_B Importin subunit alpha, Large T; ARM repeat, NLS, nuclear import; 1.7553A {Neurospora crassa}
Probab=98.05  E-value=1.2e-09  Score=113.39  Aligned_cols=157  Identities=18%  Similarity=0.227  Sum_probs=116.8  Template_Neff=12.500

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.++.++. +.++.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       196 ~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  269 (495)
T 4RXH_B          196 IAPALPVLAKLVY-SLDDEVLIDACWAISYLSDGSND-----KIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVT  269 (495)
T ss_dssp             HTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTSSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             hcCHHHHHHHHhh-CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCChHHHHHHHHhcCCccHHHHHHHHHHHHhc
Confidence            3456777888887 46778888999999998864332     22333455788888888888888899999999999987


Q NP_000290.2     625 HP-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      .. .. ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.|..++.+. ++.++.
T Consensus       270 ~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~  342 (495)
T 4RXH_B          270 GDDVQTQVIINCGALPCLLSLLSS------NKDGIRKEACWTISNITAGNSAQIQSVIDANIIPPLIHLLSHA-DLKTRK  342 (495)
T ss_dssp             SCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHSS-CHHHHH
T ss_pred             CCHHHHHHHHhCCHHHHHHHHHhC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHHhcC-CHHHHH
Confidence            63 22 233445677888888876      3678899999999999876554444555556788888888766 778899


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       343 ~a~~~l~~l~~~  354 (495)
T 4RXH_B          343 EACWAISNATSG  354 (495)
T ss_dssp             HHHHHHHHTTTT
T ss_pred             HHHHHHHHHHhc
Confidence            999999998876


No 41
>5XJG_A Vacuolar protein 8, Nucleus-vacuole junction; Vac8p, Nvj1p, Membrane contact site; HET: B3P, PE5; 2.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=98.04  E-value=1.3e-09  Score=111.79  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=82.5  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       159 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  237 (506)
T 5XJG_A          159 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  237 (506)
T ss_dssp             THHHHHHHTTCSSHHHHHHHHHHHHHTCSSH-HHHHHHHHHTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHcCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHH
Confidence            4555666666667788888899988887542 222233334567777777777777888888998888875433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       238 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  293 (506)
T 5XJG_A          238 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  293 (506)
T ss_dssp             HHCTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSHHHHHHHHHTTHHHHHHHHHT
T ss_pred             hhChhHHHHHHHHcc-CCCHHHHHHHHHHHHHHhCCChhHHHHHHcCcHHHHHHHHh
Confidence             11235666677775 45667788888888888765433333332 45555555554


No 42
>6KBM_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 2.902A {Saccharomyces cerevisiae}
Probab=98.04  E-value=1.3e-09  Score=111.79  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=82.5  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       159 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  237 (506)
T 6KBM_A          159 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  237 (506)
T ss_dssp             THHHHHHHTTCSSHHHHHHHHHHHHHTCSSH-HHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHcCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHH
Confidence            4555666666667788888899988887542 222233334567777777777777888888998888875433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       238 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  293 (506)
T 6KBM_A          238 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  293 (506)
T ss_dssp             HHCTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHTSHHHHHHHHHTTCHHHHHHHHT
T ss_pred             hhChhHHHHHHHHcc-CCCHHHHHHHHHHHHHHhCCChhHHHHHHcCcHHHHHHHHh
Confidence             11235666677775 45667788888888888765433333332 45555555554


No 43
>4TNM_A Importin-alpha3 / MOS6; armadillo repeat; 2.9A {Arabidopsis thaliana}
Probab=97.99  E-value=2e-09  Score=113.28  Aligned_cols=158  Identities=18%  Similarity=0.255  Sum_probs=115.7  Template_Neff=12.300

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.|+.++. +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.
T Consensus       243 ~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~  316 (531)
T 4TNM_A          243 TQPALPVLERLVQ-SMDEEVLTDACWALSYLSDNSND-----KIQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIVT  316 (531)
T ss_pred             hcchHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCHH-----HHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHC
Confidence            3456777777777 46777888999999998865332     22333456788889999988888899999999999987


Q NP_000290.2     625 HPLL--HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~e~--~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      ....  ......++++.+..++...     .++.++..++.+|.+++...+.....+...++++.|+.++.+. ++.++.
T Consensus       317 ~~~~~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  390 (531)
T 4TNM_A          317 GDDLQTQMVLDQQALPCLLNLLKNN-----YKKSIKKEACWTISNITAGNADQIQAVIDAGIIQSLVWVLQSA-EFEVKK  390 (531)
T ss_pred             CCHHHHHHHHHCCcHHHHHHHhcCC-----CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhcCC-CHHHHH
Confidence            6322  2333446777888877652     2567888999999999876545555555666788888888765 778888


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       391 ~a~~~l~~l~~~  402 (531)
T 4TNM_A          391 EAAWGISNATSG  402 (531)
T ss_pred             HHHHHHHHHHcC
Confidence            899999888864


No 44
>6KBN_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.98  E-value=2.1e-09  Score=112.87  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=86.0  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       153 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  231 (563)
T 6KBN_A          153 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  231 (563)
T ss_dssp             THHHHHHHTTCSSHHHHHHHHHHHHHTTSSH-HHHHHHHTTTCHHHHHHHTTCSSHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHhCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCCHHHHHHHH
Confidence            4555666666667788888999998887542 222233334577777777777777888899999988876433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       232 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  287 (563)
T 6KBN_A          232 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  287 (563)
T ss_dssp             HHCSSHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSHHHHHHHHHTTCHHHHHHHHT
T ss_pred             hhchhHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCChhHHHHHHHCCcHHHHHHHHh
Confidence             11236667777775 55677888899999988875443333333 56677776664


No 45
>6KBN_C Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.98  E-value=2.1e-09  Score=112.87  Aligned_cols=133  Identities=20%  Similarity=0.248  Sum_probs=86.0  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.... .....+...++++.+...+.+.+..++..++.++..++..........
T Consensus       153 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  231 (563)
T 6KBN_C          153 ALIPLTKLAKSKHIRVQRNATGALLNMTHSE-ENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLA  231 (563)
T ss_dssp             CHHHHHHHTTSSSHHHHHHHHHHHHHHTSSH-HHHHHHHTTTCHHHHHHHTTCSSHHHHHHHHHHHHHHTTSHHHHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHhCCH-HHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCCHHHHHHHH
Confidence            4555666666667788888999998887542 222233334577777777777777888899999988876433221111


Q NP_000290.2     326 -RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 -l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                       ...++++.+...+. ..++.++..++.++..++........+.. ++++.+..++.
T Consensus       232 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~  287 (563)
T 6KBN_C          232 QTEPRLVSKLVSLMD-SPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQ  287 (563)
T ss_dssp             HSSTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSHHHHHHHHHTTCHHHHHHHTT
T ss_pred             hhchhHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCChhHHHHHHHCCcHHHHHHHHh
Confidence             11236667777775 55677888899999988875443333333 56677776664


No 46
>4EV8_A Catenin beta-1; mouse catenin, CELL ADHESION; HET: URE; 1.9A {Mus musculus}
Probab=97.98  E-value=2.1e-09  Score=111.06  Aligned_cols=323  Identities=18%  Similarity=0.194  Sum_probs=192.8  Template_Neff=13.100

Q NP_000290.2     286 LGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRR-QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK  364 (747)
Q Consensus       286 ~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~-~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~  364 (747)
                      .++++.+...+.+.++.++..++.++..+....... ..+.. .+++..+...+....++.++..++.++..++......
T Consensus        17 ~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~-~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~   95 (538)
T 4EV8_A           17 TRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASR-HAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGL   95 (538)
T ss_pred             cCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCChhhH-HHHHhCCChHHHHHHHhcCCCCHHHHHHHHHHHHHHcCCHHHH
Confidence            356677777777777888888999998887643322 12222 2466677776653446678888999999887654433


Q NP_000290.2     365 EELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQT  443 (747)
Q Consensus       365 ~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  443 (747)
                      ..+.. ++++.|+.++..+                ++++...+..+|..-...      .              +..++.
T Consensus        96 ~~~~~~~~~~~l~~~l~~~----------------~~~~~~~a~~~l~~l~~~------~--------------~~~~~~  139 (538)
T 4EV8_A           96 LAIFKSGGIPALVKMLGSP----------------VDSVLFYAITTLHNLLLH------Q--------------EGAKMA  139 (538)
T ss_pred             HHHHHCCcHHHHHHHhCCC----------------CHHHHHHHHHHHHHHhCC------C--------------HHHHHH
Confidence            33333 6777777776532                344444444333221100      0              000000


Q NP_000290.2     444 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN  523 (747)
Q Consensus       444 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  523 (747)
                      . .-.+++..|...++.      -+..-...+...|.++...                                      
T Consensus       140 ~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~--------------------------------------  174 (538)
T 4EV8_A          140 V-RLAGGLQKMVALLNK------TNVKFLAITTDCLQILAYG--------------------------------------  174 (538)
T ss_pred             H-HHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHhcC--------------------------------------
Confidence            0 012444444444332      0112222222233332210                                      


Q NP_000290.2     524 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL  603 (747)
Q Consensus       524 ~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~L  603 (747)
                                  +......+.+.++++.|+.++....+..++..++.+|.+++.....      ...+...++++.+..+
T Consensus       175 ------------~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~  236 (538)
T 4EV8_A          175 ------------NQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSN------KPAIVEAGGMQALGLH  236 (538)
T ss_pred             ------------CHHHHHHHHHCChHHHHHHHHcCCCCHHHHHHHHHHHHHHcCCHHH------HHHHHHCCcHHHHHHH
Confidence                        0011112245667888888887423667788899999988865321      2333456788889999


Q NP_000290.2     604 LQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSS  683 (747)
Q Consensus       604 L~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~g  683 (747)
                      +.+.++.++..++.+|.+++......... .++++.+..++.+      .++.++..++.+|.+++...+.....+...+
T Consensus       237 l~~~~~~~~~~a~~~l~~l~~~~~~~~~~-~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~  309 (538)
T 4EV8_A          237 LTDPSQRLVQNCLWTLRNLSDAATKQEGM-EGLLGTLVQLLGS------DDINVVTCAAGILSNLTCNNYKNKMMVCQVG  309 (538)
T ss_pred             hcCCCHHHHHHHHHHHHHHHcCCCchHHH-cCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCC
Confidence            98888889999999999998763221111 3466777777765      3678888999999999765555555555666


Q NP_000290.2     684 MLNNIINLCR--SSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       684 iL~~Ll~LL~--s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .++.++..+.  .. ++.++..++.+|.+++...+
T Consensus       310 ~~~~l~~~l~~~~~-~~~~~~~a~~~l~~l~~~~~  343 (538)
T 4EV8_A          310 GIEALVRTVLRAGD-REDITEPAICALRHLTSRHQ  343 (538)
T ss_pred             cHHHHHHHHhcCCC-CHHHHHHHHHHHHHHHcCCC
Confidence            7777777665  23 56677788888888876554


No 47
>4BPL_A IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS; TRANSPORT PROTEIN, NUCLEAR IMPORT, NUCLEAR; 2.3A {ORYZA SATIVA}
Probab=97.98  E-value=2.2e-09  Score=108.63  Aligned_cols=158  Identities=18%  Similarity=0.251  Sum_probs=116.0  Template_Neff=13.000

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.|+.++. +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       168 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  241 (454)
T 4BPL_A          168 TRPALPALARLIH-SNDEEVLTDACWALSYLSDGTND-----KIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVT  241 (454)
T ss_dssp             HTTHHHHHHHHTT-CCCHHHHHHHHHHHHHHTSSCHH-----HHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHHHHh-CCCHHHHHHHHHHHHHHhcCChH-----HHHHHHHCCcHHHHHHHhhCCChHHHHHHHHHHHHHhc
Confidence            3456777777777 46777888899999998865332     22333455788888898888888899999999999987


Q NP_000290.2     625 HPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      ... . ..+...++++.+..++...     .++.++..++.+|.+++...+.....+...++++.|..++.+. ++.++.
T Consensus       242 ~~~~~~~~~~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  315 (454)
T 4BPL_A          242 GDDAQTQCIIDHQALPCLLSLLTQN-----LKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTA-EFDIKK  315 (454)
T ss_dssp             SCHHHHHHHHTTTHHHHHHHHHHSS-----CCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHHHHHS-CHHHHH
T ss_pred             CCHHHHHHHHHCChHHHHHHHHHhc-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCcHHHHHHHhhcC-CHHHHH
Confidence            632 2 2334456777888887652     2577889999999999876555555555666788888888766 778888


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       316 ~a~~~l~~l~~~  327 (454)
T 4BPL_A          316 EAAWAISNATSG  327 (454)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHcC
Confidence            899999888863


No 48
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=97.96  E-value=2.5e-09  Score=100.09  Aligned_cols=112  Identities=25%  Similarity=0.272  Sum_probs=72.2  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........+.
T Consensus         3 i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   82 (281)
T 4PLS_B            3 LPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVI   82 (281)
T ss_dssp             HHHHHHTTTCSCHHHHHHHHHHHHHHHTCSHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHH
Confidence            34556666667778888899999888765444333444455777777877777778888888888888754333222333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ..++++.+...+. +.++.++..++.++..++.
T Consensus        83 ~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  114 (281)
T 4PLS_B           83 DAGALPALVQLLS-SPNEQILQEALWTLGNIAS  114 (281)
T ss_dssp             HTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHTT
T ss_pred             hCCcHHHHHHHcC-CCCHHHHHHHHHHHHHHhc
Confidence            3345566666665 4455666666666666654


No 49
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=97.95  E-value=2.6e-09  Score=104.87  Aligned_cols=123  Identities=24%  Similarity=0.347  Sum_probs=80.3  Template_Neff=12.500

Q NP_000290.2     258 DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLETRRQNGIREAV  335 (747)
Q Consensus       258 d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~ll~~~IL~~Ll  335 (747)
                      ++.++..++.++.+++...+.....+.. .++++.+..++...++.++..++.++.+++.. .......+...++++.+.
T Consensus        92 ~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  171 (339)
T 5Z8H_A           92 SITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALM  171 (339)
T ss_pred             CHHHHHHHHHHHHHHcCCCHHHHHHHHHhcChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCCHHHHHHHHHCCcHHHHH
Confidence            6778888999999887644443333444 46778888888777788889999999998864 222223333456777777


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSS-TDELKEELIA--DALPVLADRVI  380 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas-~~~~~~~Lve--giLe~Lv~LL~  380 (747)
                      ..+....++.++..++.++.+++. .......+..  ++++.++.++.
T Consensus       172 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  219 (339)
T 5Z8H_A          172 ECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT  219 (339)
T ss_pred             HHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHhcChHHHHHHHhc
Confidence            777622466778888888888876 3333323322  45555555554


No 50
>2Z6H_A Catenin beta-1; Beta-Catenin, C-terminal Domain, Activator, Cell; 2.2A {Homo sapiens}
Probab=97.95  E-value=2.8e-09  Score=116.50  Aligned_cols=415  Identities=18%  Similarity=0.223  Sum_probs=234.1  Template_Neff=11.700

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ++..+...+. ..+..++..++.+|..++.... ....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        57 ~i~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~-~~~~~~~~~~i~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  135 (644)
T 2Z6H_A           57 MVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE-GLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA  135 (644)
T ss_pred             hHHHHHHHHcCCCCHHHHHHHHHHHHHHhCCHH-HHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4455555555 4566778888888888865432 2223334567778888887777888899999999888654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..+..++..++.++..++.... ....+.. ++++.|+.++...               .++++
T Consensus       136 ~~~~~~~~~L~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~---------------~~~~~  199 (644)
T 2Z6H_A          136 VRLAGGLQKMVALLN-KTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTY---------------TYEKL  199 (644)
T ss_pred             HHHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhcCC---------------CCHHH
Confidence            333467777877776 5567888889999999886432 2223333 6777777777642               12233


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-..                     .+..+..+ ...+.++.|...+..      .+....++++..|.++
T Consensus       200 ~~~a~~~L~~l~~---------------------~~~~~~~~-~~~~~l~~l~~~l~~------~~~~~~~~a~~~L~~l  251 (644)
T 2Z6H_A          200 LWTTSRVLKVLSV---------------------CSSNKPAI-VEAGGMQALGLHLTD------PSQRLVQNCLWTLRNL  251 (644)
T ss_pred             HHHHHHHHHHHcc---------------------ChHHHHHH-HHCCHHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            3333333321100                     00000000 012334444333321      1334445566666666


Q NP_000290.2     483 SYRLDAE------VPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLM  556 (747)
Q Consensus       483 ~~~~~~~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL  556 (747)
                      .......      ++.-...+..  .+.-.......++.+               ....+......+.+.++++.|+..+
T Consensus       252 ~~~~~~~~~~~~~~~~l~~~l~~--~~~~v~~~a~~~L~~---------------l~~~~~~~~~~~~~~~~l~~L~~~l  314 (644)
T 2Z6H_A          252 SDAATKQEGMEGLLGTLVQLLGS--DDINVVTCAAGILSN---------------LTCNNYKNKMMVCQVGGIEALVRTV  314 (644)
T ss_pred             hcCCCCHHHHCchHHHHHHHhcC--CCHHHHHHHHHHHHH---------------HhCCCHHHHHHHHhCCHHHHHHHHH
Confidence            5432210      0000000000  000000001111111               0011112223345667888888877


Q NP_000290.2     557 GK-SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHPLL-HRVMG  633 (747)
Q Consensus       557 ~s-s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~e~-~~ll~  633 (747)
                      .. ..++.++..++.+|.+++.....  .......+...++++.|+.++.+. +..++..++.+|.+++..... ..+..
T Consensus       315 ~~~~~~~~v~~~a~~~L~~l~~~~~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~l~~  392 (644)
T 2Z6H_A          315 LRAGDREDITEPAICALRHLTSRHQE--AEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLRE  392 (644)
T ss_pred             hcCCCCHHHHHHHHHHHHHHHcCCCC--HHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHH
Confidence            52 14567788899999999875331  000012223457788888888765 678889999999999876433 23344


Q NP_000290.2     634 NQVFPEVTRLLTSHTGN----------------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSAS  697 (747)
Q Consensus       634 ~giI~~Ll~LL~s~s~~----------------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d  697 (747)
                      .++++.|+.++......                ......++..++.+|.+++... .....+...++++.|+.++.+. +
T Consensus       393 ~~~~~~L~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~L~~l~~~~-~~~~~~~~~~~i~~l~~~l~~~-~  470 (644)
T 2Z6H_A          393 QGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDV-HNRIVIRGLNTIPLFVQLLYSP-I  470 (644)
T ss_pred             CCcHHHHHHHHccCCHHHHHHHhcCCchhhhhcCCCCHHHHHHHHHHHHHHhcCc-chHHHHHHCCcHHHHHHHHhCC-C
Confidence            56777777777652100                0002347788999999998753 3334444556788888888776 7


Q NP_000290.2     698 PKAAEAARLLLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       698 ~eVr~aAL~aLsnL~~~~~~~~~~~~~~~  726 (747)
                      +.++..++.+|.+++...+....+...|+
T Consensus       471 ~~v~~~a~~~L~~l~~~~~~~~~~~~~~~  499 (644)
T 2Z6H_A          471 ENIQRVAAGVLCELAQDKEAAEAIEAEGA  499 (644)
T ss_pred             HHHHHHHHHHHHHHhcCHHHHHHHHHCCc
Confidence            88999999999999987766555544443


No 51
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=97.94  E-value=2.9e-09  Score=99.92  Aligned_cols=114  Identities=25%  Similarity=0.274  Sum_probs=73.1  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (286)
T 5AEI_B            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV   84 (286)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888999988876544333334444567777777777777888888888888875433322223


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. +.++.++..++.++..++..
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  118 (286)
T 5AEI_B           85 IDAGALPALVQLLS-SPNEQILQEALWALSNIASG  118 (286)
T ss_dssp             HHHTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHcChHHHHHHHhh-CCCHHHHHHHHHHHHHHhCC
Confidence            33345566666665 44556666677777666643


No 52
>4B8J_A IMPORTIN SUBUNIT ALPHA-1A; TRANSPORT PROTEIN, NUCLEAR LOCALIZATION SIGNAL; 2.001A {ORYZA SATIVA JAPONICA GROUP}
Probab=97.93  E-value=3.2e-09  Score=111.25  Aligned_cols=160  Identities=20%  Similarity=0.243  Sum_probs=114.5  Template_Neff=12.400

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .+.++++.++..+....++.++..++.+|.+++.....      .......++++.|..++.+.++.++..++.+|.+++
T Consensus       199 ~~~~~l~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~  272 (528)
T 4B8J_A          199 LANGALLPLLAQLNEHTKLSMLRNATWTLSNFCRGKPQ------PSFEQTRPALPALARLIHSNDEEVLTDACWALSYLS  272 (528)
T ss_dssp             HHTTCHHHHHHTCCTTCCHHHHHHHHHHHHHHHCSSSC------CCHHHHTTHHHHHHHHTTCCCHHHHHHHHHHHHHHT
T ss_pred             HHCCcHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCCC------CCHHHHhhHHHHHHHHhcCCCHHHHHHHHHHHHHHh
Confidence            34556777777765334567788899999998865321      222234578888888888888889999999999998


Q NP_000290.2     624 RH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .. ... ..+...++++.++.++.+      .++.++..++.+|.+++...+.....+...++++.|+.++.+..+..++
T Consensus       273 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~  346 (528)
T 4B8J_A          273 DGTNDKIQAVIEAGVCPRLVELLLH------PSPSVLIPALRTVGNIVTGDDAQTQCIIDHQALPCLLSLLTQNLKKSIK  346 (528)
T ss_dssp             SSCHHHHHHHHHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTHHHHHHHHHHSCCCHHHH
T ss_pred             cCChHHHHHHHHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHHhcCCCHHHH
Confidence            76 222 233445677888888776      3678889999999999875454444555556788888887654356788


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       347 ~~a~~~l~~l~~~~  360 (528)
T 4B8J_A          347 KEACWTISNITAGN  360 (528)
T ss_dssp             HHHHHHHHHHHTSC
T ss_pred             HHHHHHHHHHHcCC
Confidence            89999999987543


No 53
>4R10_A Protein humpback-2, Cadherin-related hmr-1; armadillo repeat, cell adhesion, phosphorylation; HET: SEP; 2.3A {Caenorhabditis elegans}
Probab=97.89  E-value=4.1e-09  Score=110.79  Aligned_cols=417  Identities=14%  Similarity=0.174  Sum_probs=224.8  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.+|..+.... .....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        73 ~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  151 (572)
T 4R10_A           73 SFVEALMAASKSSNVNVRRNAIGALSHMSEQR-GGPLLIFRSGGLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQ  151 (572)
T ss_dssp             HHHHHHHHHTTCSCHHHHHHHHHHHHHHTTST-THHHHHHHTTTHHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTHHHHH
T ss_pred             cHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCC-ChHHHHHhCCcHHHHHHHHhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            44566666676677788888999998887643 22233334567777777777777888899999999887544333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+...+. ..++.++..++.++..++... .....+.. ++++.+..++...              ..++++
T Consensus       152 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~--------------~~~~~~  216 (572)
T 4R10_A          152 ARALNAVEALTPHLH-KTNPKLLAQVADGLYFLLIDDAPSKITFLSLLGPQILVSILREY--------------SDHRKL  216 (572)
T ss_dssp             HHHTTHHHHHGGGGG-CCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHC--------------TTCHHH
T ss_pred             HHHCCHHHHHHHHHh-cCCHHHHHHHHHHHHHHHCCChHHHHHHHhccHHHHHHHHHHHC--------------CCCHHH
Confidence            334467777777776 556788888999999887543 22223333 6777777776521              012333


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-.                     ..+..+..+.. .+.++.+...+...     -+..-...++.+|.++
T Consensus       217 ~~~a~~~l~~l~---------------------~~~~~~~~~~~-~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l  269 (572)
T 4R10_A          217 IYTVVRCIRSLS---------------------VCPSNKPALIS-LGCLPALYVELCTA-----KDERSQTAILVAMRNL  269 (572)
T ss_dssp             HHHHHHHHHHHT---------------------TSTTHHHHHHH-TTHHHHHHHHHTTC-----CSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHh---------------------cCcchHHHHHh-CCcHHHHHHHHhcC-----CCHHHHHHHHHHHHHH
Confidence            333333332110                     00000111110 12222222211110     1223334445555555


Q NP_000290.2     483 SYRLDAE------VPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLM  556 (747)
Q Consensus       483 ~~~~~~~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL  556 (747)
                      ....+..      ++.-...+.  ..+.........++.+-               ...+......+.+.++++.|+.++
T Consensus       270 ~~~~~~~~~~~~~~~~l~~~l~--~~~~~~~~~a~~~l~~l---------------~~~~~~~~~~~~~~~~~~~l~~~l  332 (572)
T 4R10_A          270 SDSATNEENLTQLIIKLLEIIR--VANDGMTACACGTLSNL---------------TCNNTRNKQTVCSHGGIDALVTAI  332 (572)
T ss_dssp             GGGCTTCSCCHHHHHHHHHHHH--HCCHHHHHHHHHHHHHH---------------TSSCHHHHHHHHHTTHHHHHHHHH
T ss_pred             cCChHHHHHHHHHHHHHHHHhc--CCCHHHHHHHHHHHHHH---------------HcCCHHHHHHHHHCcHHHHHHHHH
Confidence            4322110      000000000  00000001111111111               111112233345778888898888


Q NP_000290.2     557 GK-SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMG-  633 (747)
Q Consensus       557 ~s-s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~-  633 (747)
                      .. ..++.++..++++|.+++..... ... ....+...++++.+..++.+.+..++..++.+|.+++..... ..+.. 
T Consensus       333 ~~~~~~~~~~~~a~~~l~~l~~~~~~-~~~-~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~  410 (572)
T 4R10_A          333 RRLPEVEEVTEPALCALRHCTARHSL-AEE-AQSELRFCQAFPVILDQLETLRTPVIKAALGVIRNSALLQTNLIELTQE  410 (572)
T ss_dssp             HHSTTCHHHHHHHHHHHHHHTSSSTT-HHH-HHHHHHHTTHHHHHHHHHTTCCHHHHHHHHHHHHHHHTSHHHHHHHHHC
T ss_pred             HhCCCcHHHHHHHHHHHHHhhccCCC-cHH-HHHHHhhCChHHHHHHHHhcCCHHHHHHHHHHHHHHhccchhHHHHHHH
Confidence            62 23446888999999999432110 000 122233467888889998888888999999999999876332 22222 


Q NP_000290.2     634 -----NQVFPEVTRLLTSHTG----------NTSNSEDILSSACYTVRNLMASQPQLAKQYFSS----------SMLNNI  688 (747)
Q Consensus       634 -----~giI~~Ll~LL~s~s~----------~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~----------giL~~L  688 (747)
                           .++++.+..++.....          ....++.++..++.+|.+++.. +.....+...          ++++.|
T Consensus       411 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~~~~~~~~~~~l  489 (572)
T 4R10_A          411 QTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVIEGAVSALHQLANH-PAVAAACCDDIGQVGNPECPPFLDLL  489 (572)
T ss_dssp             CCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHHHHHHHHHHHHTTS-HHHHHHHHHCCCCTTCTTSCCHHHHH
T ss_pred             hhhCCCCcHHHHHHHHHHHHHhcccCcchhccCccHHHHHHHHHHHHHHHhCC-HHHHHHHhccccCCCCCCCccHHHHH
Confidence                 2344555555432000          0012356777888899988764 3333333332          567777


Q NP_000290.2     689 INLC------RSSASPKAAEAARLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       689 l~LL------~s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~  725 (747)
                      ..++      ... ++.++..++.+|.+++...+....+...|
T Consensus       490 ~~~l~~~~~~~~~-~~~v~~~a~~~l~~l~~~~~~~~~~~~~~  531 (572)
T 4R10_A          490 HRLLAHPRLGSMD-DEVLEREILGLLYQLSKRPDGARAVESTG  531 (572)
T ss_dssp             HHHHHSHHHHSCS-CSHHHHHHHHHHHHHTSSHHHHHHHHTTT
T ss_pred             HHHHhCcccCCCC-hHHHHHHHHHHHHHHhcCCchhhHHHHcC
Confidence            7777      444 77899999999999998766544443333


No 54
>5XJG_A Vacuolar protein 8, Nucleus-vacuole junction; Vac8p, Nvj1p, Membrane contact site; HET: B3P, PE5; 2.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.89  E-value=4.2e-09  Score=107.74  Aligned_cols=359  Identities=22%  Similarity=0.262  Sum_probs=200.2  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.......    ...++++.+...+.+.++.++..++.++..++..... ....
T Consensus        39 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~-~~~~  113 (506)
T 5XJG_A           39 PLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLLI  113 (506)
T ss_dssp             HHHHHHHHHTTCCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSHHH-HHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHhchHHH----HhhccHHHHHHHhhCCCHHHHHHHHHHHHHHHcCchh-HHHH
Confidence            4455555666666777777777777776532211    1234566666666666667777777777777654321 1222


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+. +.++.++..++.++..++........+.. ++++.+..++...                ++++-.
T Consensus       114 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  176 (506)
T 5XJG_A          114 VEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQR  176 (506)
T ss_dssp             HHTTTHHHHHHHHT-SSCHHHHHHHHHHHHHHTTSHHHHHHHHTTTTHHHHHHHTTCS----------------SHHHHH
T ss_pred             HhcCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhcCcchhhHHHhcccHHHHHHHccCC----------------CHHHHH
Confidence            23345666666665 45566777777777777654332222222 4555555555421                223322


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-         .            .....+..+. ..+.++.+...++.      .+..-...+...|.++..
T Consensus       177 ~a~~~l~~l---------~------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~  228 (506)
T 5XJG_A          177 NATGALLNM---------T------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIAV  228 (506)
T ss_dssp             HHHHHHHHT---------C------------SSHHHHHHHH-HHTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHH---------c------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhc
Confidence            222222210         0            0000000000 02333333333221      011222223333333221


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT  564 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV  564 (747)
                      ..+                                                . .........++++.++.++. ..++.+
T Consensus       229 ~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~~  258 (506)
T 5XJG_A          229 DEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSRV  258 (506)
T ss_dssp             SHH------------------------------------------------H-HHHHHHHCTTHHHHHHHHTT-CSSHHH
T ss_pred             CHH------------------------------------------------H-HHHHHhhChhHHHHHHHHcc-CCCHHH
Confidence            000                                                0 00000012346777888887 466778


Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRL  643 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~L  643 (747)
                      +..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..+
T Consensus       259 ~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~  332 (506)
T 5XJG_A          259 KCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRL  332 (506)
T ss_dssp             HHHHHHHHHHHTTSHHH------HHHHHHTTHHHHHHHHHTCSSHHHHHHHHHHHHHHTTSGGGHHHHHHTTCHHHHHHG
T ss_pred             HHHHHHHHHHHhCCChh------HHHHHHcCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHHH
Confidence            88899999998875321      22334567888888888888888999999999999876433 233445677788888


Q NP_000290.2     644 LTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       644 L~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +...     .++.++..++++|.+++...+.....+...++++.+..++.+. ++.++..++.++..+....+
T Consensus       333 l~~~-----~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~~~  399 (506)
T 5XJG_A          333 LDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALADV  399 (506)
T ss_dssp             GGCT-----TCHHHHHHHHHHHHHTSSCCHHHHHHHHTTTHHHHHHHHTTSS-CHHHHHHHHHHHHHHTTCHH
T ss_pred             HcCC-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHhCChhHHHHHHHhcC-CHHHHHHHHHHHHHHhccch
Confidence            7652     2467888999999999875544444555556677777777655 56677777777776665443


No 55
>6KBM_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 2.902A {Saccharomyces cerevisiae}
Probab=97.89  E-value=4.2e-09  Score=107.74  Aligned_cols=359  Identities=22%  Similarity=0.262  Sum_probs=200.2  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+.......    ...++++.+...+.+.++.++..++.++..++..... ....
T Consensus        39 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~-~~~~  113 (506)
T 6KBM_A           39 PLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLLI  113 (506)
T ss_dssp             HHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHTTCCCHHHHHHHHHHHHHHTTSHHH-HHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHhchHHH----HhhccHHHHHHHhhCCCHHHHHHHHHHHHHHHcCchh-HHHH
Confidence            4455555666666777777777777776532211    1234566666666666667777777777777654321 1222


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFF  404 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~  404 (747)
                      ...++++.+...+. +.++.++..++.++..++........+.. ++++.+..++...                ++++-.
T Consensus       114 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~~  176 (506)
T 6KBM_A          114 VEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQR  176 (506)
T ss_dssp             HHTTTHHHHHHHHT-SCCHHHHHHHHHHHHHHTTSHHHHHHHHTTTTHHHHHHHTTCS----------------SHHHHH
T ss_pred             HhcCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhcCcchhhHHHhcccHHHHHHHccCC----------------CHHHHH
Confidence            23345666666665 45566777777777777654332222222 4555555555421                223322


Q NP_000290.2     405 NATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSY  484 (747)
Q Consensus       405 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  484 (747)
                      .+..++..-         .            .....+..+. ..+.++.+...++.      .+..-...+...|.++..
T Consensus       177 ~a~~~l~~l---------~------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~  228 (506)
T 6KBM_A          177 NATGALLNM---------T------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIAV  228 (506)
T ss_dssp             HHHHHHHHT---------C------------SSHHHHHHHH-HTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHH---------c------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhc
Confidence            222222210         0            0000000000 02333333333221      011222223333333221


Q NP_000290.2     485 RLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT  564 (747)
Q Consensus       485 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV  564 (747)
                      ..+                                                . .........++++.++.++. ..++.+
T Consensus       229 ~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~~  258 (506)
T 6KBM_A          229 DEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSRV  258 (506)
T ss_dssp             SHH------------------------------------------------H-HHHHHHHCTTHHHHHHHHTT-CSSHHH
T ss_pred             CHH------------------------------------------------H-HHHHHhhChhHHHHHHHHcc-CCCHHH
Confidence            000                                                0 00000012346777888887 466778


Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRL  643 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~L  643 (747)
                      +..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..+
T Consensus       259 ~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~  332 (506)
T 6KBM_A          259 KCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRL  332 (506)
T ss_dssp             HHHHHHHHHHHHTSHHH------HHHHHHTTCHHHHHHHHTSSCHHHHHHHHHHHHHHTTSGGGHHHHHHTTCHHHHHHH
T ss_pred             HHHHHHHHHHHhCCChh------HHHHHHcCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHHH
Confidence            88899999998875321      22334567888888888888888999999999999876433 233445677788888


Q NP_000290.2     644 LTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       644 L~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +...     .++.++..++++|.+++...+.....+...++++.+..++.+. ++.++..++.++..+....+
T Consensus       333 l~~~-----~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~~~  399 (506)
T 6KBM_A          333 LDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALADV  399 (506)
T ss_dssp             TTCC-----SCHHHHHHHHHHHHHHHHHCSSTHHHHHHTTHHHHHHHHSSSS-CHHHHHHHHHHHHHHTTCHH
T ss_pred             HcCC-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHhCChhHHHHHHHhcC-CHHHHHHHHHHHHHHhccch
Confidence            7652     2467888999999999875544444555556677777777655 56677777777776665443


No 56
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=97.89  E-value=4.5e-09  Score=105.07  Aligned_cols=297  Identities=19%  Similarity=0.226  Sum_probs=180.6  Template_Neff=12.000

Q NP_000290.2     236 CSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-----------NQNVQ  304 (747)
Q Consensus       236 ~~~~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-----------d~eVr  304 (747)
                      |.+-++..+.........+.+.++.++..++.+|.++... ......+...++++.+..++...           +..++
T Consensus        23 ~~~~~~~~~~~~~~~~~~l~~~~~~~~~~a~~~L~~l~~~-~~~~~~~~~~~~~~~L~~~l~~~~~~~~~~~~~~~~~~~  101 (354)
T 5IZA_A           23 CWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFD-EEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLR  101 (354)
T ss_dssp             HHHHHHHCCTTCCTTTSCCCCGGGGTHHHHHHHHHHHTTS-HHHHHHHHHTTHHHHHHHHHHHHHHHHCSCCCHHHHHHH
T ss_pred             HHHHHHhcCCCCCCCCCCCCCCchHhHHHHHHHHHHccCC-HHHHHHHHHcCHHHHHHHHHHhhHHHhCCCCCCCCHHHH
Confidence            3343444444444445556667778888899999998765 33333344456777777777643           67788


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKLETRR-QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST--DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~~ll~-~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~--~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.++.+++.........+.. .++++.+..++. ..++.++..++.++.+++..  ......+.. ++++.|+.++.
T Consensus       102 ~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  180 (354)
T 5IZA_A          102 RYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLK-SESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECAL  180 (354)
T ss_dssp             HHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHH
Confidence            88999999887644333333333 467777888886 55678888999999999874  222333444 77777877775


Q NP_000290.2     381 IPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       381 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      ..               .++++...+..+|..                     +... +..++.+..-.|.++.|...+.
T Consensus       181 ~~---------------~~~~~~~~a~~~L~~---------------------l~~~~~~~~~~~~~~~~~~~~l~~~l~  224 (354)
T 5IZA_A          181 EV---------------KKESTLKSVLSALWN---------------------LSAHCTENKADICAVDGALAFLVGTLT  224 (354)
T ss_dssp             HC---------------CCHHHHHHHHHHHHH---------------------HHTTCHHHHHHHHTSTTHHHHHHHHTC
T ss_pred             hc---------------CCHHHHHHHHHHHHH---------------------HHcCChHhHHHHHhhccHHHHHHHHHh
Confidence            42               133443333333322                     1111 1122222221345555555444


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ...  ...+..-.+.+..+|.+++..+.                                               .+...
T Consensus       225 ~~~--~~~~~~~~~~~~~~L~~l~~~~~-----------------------------------------------~~~~~  255 (354)
T 5IZA_A          225 YRS--QTNTLAIIESGGGILRNVSSLIA-----------------------------------------------TNEDH  255 (354)
T ss_dssp             SSC--SSCCHHHHHHHHHHHHHHHHHHT-----------------------------------------------TCHHH
T ss_pred             hcC--CCCcHHHHHHHHHHHHHHHHHhc-----------------------------------------------CCHHH
Confidence            210  11113334555556666541100                                               01112


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL  619 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aL  619 (747)
                      ...+.+.++++.|+.++. ..++.++..++.+|.+++...+.     ....+.+.++++.|+.++.+.++.++..++.+|
T Consensus       256 ~~~l~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L  329 (354)
T 5IZA_A          256 RQILRENNCLQTLLQHLK-SHSLTIVSNACGTLWNLSARNPK-----DQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL  329 (354)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTSSCHH-----HHHHHHHTTHHHHHHTTTTCSSHHHHHHHHHHH
T ss_pred             HHHHHHCCHHHHHHHHhh-cCCHHHHHHHHHHHHHHHccCHH-----HHHHHHhCCHHHHHHHHHhccCHHHHHHHHHHH
Confidence            223356678888988887 46777888999999999874332     233445678899999999888888999999999


Q NP_000290.2     620 SNMSRH  625 (747)
Q Consensus       620 snLa~~  625 (747)
                      .+++..
T Consensus       330 ~~l~~~  335 (354)
T 5IZA_A          330 RNLMAN  335 (354)
T ss_dssp             HHHHHT
T ss_pred             HHHHcc
Confidence            999876


No 57
>4R0Z_A Protein humpback-2; armadillo repeat, cell adhesion; 2.005A {Caenorhabditis elegans}
Probab=97.86  E-value=5.4e-09  Score=112.30  Aligned_cols=401  Identities=14%  Similarity=0.143  Sum_probs=217.2  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++.........+...++++.+..++...+..++..++.++..++.........+
T Consensus       115 ~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~  194 (629)
T 4R0Z_A          115 GLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQARALNAVEALTPHLHKTNPKLLAQVADGLYFLLIDDAPSKITF  194 (629)
T ss_dssp             CHHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTTHHHHHHHTTHHHHHGGGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHHhCCCHHHHHHHHHHHHHHHcCChHHHHHHHHCCHHHHHHHHHhccCHHHHHHHHHHHHHHhCCCHHHHHHH
Confidence            45556666666677888889999998866543333344445677888888877778888999999999875544333334


Q NP_000290.2     326 RRQNGIREAVSLLRR-TGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~s-s~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...+++..+..++.. ..+..++..++.++..++........+.. +++..++..+...               .++++.
T Consensus       195 ~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~~~~  259 (629)
T 4R0Z_A          195 LSLLGPQILVSILREYSDHRKLIYTVVRCIRSLSVCPSNKPALISLGCLPALYVELCTA---------------KDERSQ  259 (629)
T ss_dssp             HHTTHHHHHHHHHHHCTTCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHHHHHHC---------------CCHHHH
T ss_pred             HHccHHHHHHHHHHHcCCCHHHHHHHHHHHHHHhcCcchHHHHHHCChHHHHHHHHHhC---------------CCHHHH
Confidence            444567777777651 23456777888888888765443333333 5555554444321               123333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..-                     +..++.+   .+++..+...+..      -+......+...|.++.
T Consensus       260 ~~a~~~l~~l~~~---------------------~~~~~~~---~~~i~~l~~~l~~------~~~~~~~~a~~~l~~l~  309 (629)
T 4R0Z_A          260 TAILVAMRNLSDS---------------------ATNEENL---TQLIIKLLEIIRV------ANDGMTACACGTLSNLT  309 (629)
T ss_dssp             HHHHHHHHHHGGG---------------------CCTTSCC---HHHHHHHHHHTTT------CCHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHcCC---------------------cchHHHH---HHHHHHHHHHHhc------CCHHHHHHHHHHHHHHH
Confidence            3333333221110                     0001111   1123333322211      12222333444444444


Q NP_000290.2     484 YRLDAEVP---------TRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLN  554 (747)
Q Consensus       484 ~~~~~~~~---------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~  554 (747)
                      ..-+....         .-..-+.....+.........+..+-...            ..........+.+.++++.|+.
T Consensus       310 ~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~------------~~~~~~~~~~~~~~~~~~~l~~  377 (629)
T 4R0Z_A          310 CNNTRNKQTVCSHGGIDALVTAIRRLPEVEEVTEPALCALRHCTAR------------HSLAEEAQSELRFCQAFPVILD  377 (629)
T ss_dssp             TTCHHHHHHHHHTTHHHHHHHHHHHCTTCHHHHHHHHHHHHHHTSS------------STTHHHHHHHHHHTTCHHHHHH
T ss_pred             cCCHHHHHHHHHCCHHHHHHHHHHhCCCcHHHHHHHHHHHHHhccc------------CCCcHHHHHHHhhcChHHHHHH
Confidence            22111000         00000000000000000011111110000            0001111222345677888888


Q NP_000290.2     555 LMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK------EKGLPQIARLLQS----------------GNSDVV  612 (747)
Q Consensus       555 LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie------~giI~~Ll~LL~s----------------~d~eVr  612 (747)
                      ++. +.++.++..++.+|.+++.....      ...+..      .+.++.+..++..                .+..++
T Consensus       378 ~l~-~~~~~~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~  450 (629)
T 4R0Z_A          378 QLE-TLRTPVIKAALGVIRNSALLQTN------LIELTQEQTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVI  450 (629)
T ss_dssp             HHT-TCCHHHHHHHHHHHHHHTTSTTH------HHHHHHCCCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHH
T ss_pred             HHh-cCCHHHHHHHHHHHHHHcccchh------HHHHHhccccCCccHHHHHHHHHHHHHHhcccCCCcccCCeeHHHHH
Confidence            887 46778888999999998865321      111122      3456666666643                234566


Q NP_000290.2     613 RSGASLLSNMSRHPLL-HRVMGN----------QVFPEVTRLLT------SHTGNTSNSEDILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~-~~ll~~----------giI~~Ll~LL~------s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~  675 (747)
                      ..++.+|.+++..... ..+...          ++++.+..++.      .      .++.++..++.+|.+++.. +..
T Consensus       451 ~~~~~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~------~~~~v~~~a~~~L~~l~~~-~~~  523 (629)
T 4R0Z_A          451 EGAVSALHQLANHPAVAAACCDDIGQVGNPECPPFLDLLHRLLAHPRLGSM------DDEVLEREILGLLYQLSKR-PDG  523 (629)
T ss_dssp             HHHHHHHHHHTTSHHHHHHHHHCCCCTTCTTSCCHHHHHHHHHTCHHHHTC------SCSHHHHHHHHHHHHHTSS-HHH
T ss_pred             HHHHHHHHHHhCCHHHHHHHhhccccCCCCCCCcHHHHHHHHhcCcccCCC------chHHHHHHHHHHHHHHhcC-CCh
Confidence            7778888888765333 222222          56777777775      3      3678889999999999854 445


Q NP_000290.2     676 AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKELQ  718 (747)
Q Consensus       676 ~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~~~  718 (747)
                      ...+...++++.|..++.+. ++.++..++.+|.++..+....
T Consensus       524 ~~~l~~~~~~~~L~~~l~~~-~~~v~~~a~~~L~~l~~~~~~~  565 (629)
T 4R0Z_A          524 ARAVESTGVSALLMESRGSQ-YKSVVTYANGVLSNLKRGDSAA  565 (629)
T ss_dssp             HHHHHTTTCHHHHHHHTTCS-SHHHHHHHHHHHHHHHHHHC--
T ss_pred             HhHHhhccHHHHHHHHhccC-ChhHHHHHHHHHhhccCCChhh
Confidence            55555666788888888766 7888999999999988766553


No 58
>4R0Z_A Protein humpback-2; armadillo repeat, cell adhesion; 2.005A {Caenorhabditis elegans}
Probab=97.85  E-value=5.5e-09  Score=112.24  Aligned_cols=418  Identities=14%  Similarity=0.170  Sum_probs=229.8  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.+|..+.... .....+...++++.+...+.+.+..++..++.++.+++.........
T Consensus        73 ~~~~~L~~~l~~~~~~~~~~a~~~L~~l~~~~-~~~~~~~~~~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  151 (629)
T 4R0Z_A           73 SFVEALMAASKSSNVNVRRNAIGALSHMSEQR-GGPLLIFRSGGLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQ  151 (629)
T ss_dssp             HHHHHHHHHTTCSCHHHHHHHHHHHHHHTTST-THHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTTHHHH
T ss_pred             cHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCC-CchHHHHhCCcHHHHHHHHhCCCHHHHHHHHHHHHHHHcCChHHHHH
Confidence            45566666676677888889999999887643 22233334467777888887777788889999999887544333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...++++.+..++. ..++.++..++.++.+++... .....+.. ++++.|+.++...              ..++++
T Consensus       152 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~--------------~~~~~~  216 (629)
T 4R0Z_A          152 ARALNAVEALTPHLH-KTNPKLLAQVADGLYFLLIDDAPSKITFLSLLGPQILVSILREY--------------SDHRKL  216 (629)
T ss_dssp             HHHTTHHHHHGGGGG-CCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHC--------------TTCHHH
T ss_pred             HHHCCHHHHHHHHHh-ccCHHHHHHHHHHHHHHhCCCHHHHHHHHHccHHHHHHHHHHHc--------------CCCHHH
Confidence            444467777888776 556788889999999987543 22333333 6777777777621              012233


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-..                     .+..+..+.. .+.+..++..+...     .+..-...++..|.++
T Consensus       217 ~~~a~~~l~~l~~---------------------~~~~~~~~~~-~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l  269 (629)
T 4R0Z_A          217 IYTVVRCIRSLSV---------------------CPSNKPALIS-LGCLPALYVELCTA-----KDERSQTAILVAMRNL  269 (629)
T ss_dssp             HHHHHHHHHHHTT---------------------STTHHHHHHH-TTHHHHHHHHHHHC-----CCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhc---------------------CcchHHHHHH-CChHHHHHHHHHhC-----CCHHHHHHHHHHHHHH
Confidence            3333333322110                     0001111111 12222222111110     1122334445555555


Q NP_000290.2     483 SYRLDAE------VPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLM  556 (747)
Q Consensus       483 ~~~~~~~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL  556 (747)
                      +..-+..      ++.-...+..  .+.........++.+               ....+......+.+.++++.|+.++
T Consensus       270 ~~~~~~~~~~~~~i~~l~~~l~~--~~~~~~~~a~~~l~~---------------l~~~~~~~~~~~~~~~~~~~l~~~l  332 (629)
T 4R0Z_A          270 SDSATNEENLTQLIIKLLEIIRV--ANDGMTACACGTLSN---------------LTCNNTRNKQTVCSHGGIDALVTAI  332 (629)
T ss_dssp             GGGCCTTSCCHHHHHHHHHHTTT--CCHHHHHHHHHHHHH---------------HHTTCHHHHHHHHHTTHHHHHHHHH
T ss_pred             cCCcchHHHHHHHHHHHHHHHhc--CCHHHHHHHHHHHHH---------------HHcCCHHHHHHHHHCCHHHHHHHHH
Confidence            4322110      0000000000  000000011111111               1111112233346778888888888


Q NP_000290.2     557 GK-SKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMG-  633 (747)
Q Consensus       557 ~s-s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~-  633 (747)
                      .. ..+..++..++.+|.+++..... ... ....+...++++.|+.++.+.++.++..++.+|.+++..... ..+.. 
T Consensus       333 ~~~~~~~~~~~~a~~~l~~l~~~~~~-~~~-~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~  410 (629)
T 4R0Z_A          333 RRLPEVEEVTEPALCALRHCTARHSL-AEE-AQSELRFCQAFPVILDQLETLRTPVIKAALGVIRNSALLQTNLIELTQE  410 (629)
T ss_dssp             HHCTTCHHHHHHHHHHHHHHTSSSTT-HHH-HHHHHHHTTCHHHHHHHHTTCCHHHHHHHHHHHHHHTTSTTHHHHHHHC
T ss_pred             HhCCCcHHHHHHHHHHHHHhcccCCC-cHH-HHHHHhhcChHHHHHHHHhcCCHHHHHHHHHHHHHHcccchhHHHHHhc
Confidence            62 13446888999999999432110 000 123334567788899999888888999999999999876322 22211 


Q NP_000290.2     634 -----NQVFPEVTRLLTSHTG----------NTSNSEDILSSACYTVRNLMASQPQLAKQYFSS----------SMLNNI  688 (747)
Q Consensus       634 -----~giI~~Ll~LL~s~s~----------~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~----------giL~~L  688 (747)
                           .++++.++.++.....          ....+..++..++.+|.+++.. +.....+.+.          ++++.|
T Consensus       411 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~L~~l~~~-~~~~~~~~~~~~~~~~~~~~~~~~~l  489 (629)
T 4R0Z_A          411 QTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVIEGAVSALHQLANH-PAVAAACCDDIGQVGNPECPPFLDLL  489 (629)
T ss_dssp             CCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHHHHHHHHHHHHTTS-HHHHHHHHHCCCCTTCTTSCCHHHHH
T ss_pred             cccCCccHHHHHHHHHHHHHHhcccCCCcccCCeeHHHHHHHHHHHHHHHhCC-HHHHHHHhhccccCCCCCCCcHHHHH
Confidence                 3455566666532000          0002345667788888888764 4444444443          567777


Q NP_000290.2     689 INLCR------SSASPKAAEAARLLLSDMWSSKELQGVLRQQGF  726 (747)
Q Consensus       689 l~LL~------s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~~~~  726 (747)
                      ..++.      +. ++.++..++.+|.+++...+....+...|.
T Consensus       490 ~~~l~~~~~~~~~-~~~v~~~a~~~L~~l~~~~~~~~~l~~~~~  532 (629)
T 4R0Z_A          490 HRLLAHPRLGSMD-DEVLEREILGLLYQLSKRPDGARAVESTGV  532 (629)
T ss_dssp             HHHHTCHHHHTCS-CSHHHHHHHHHHHHHTSSHHHHHHHHTTTC
T ss_pred             HHHhcCcccCCCc-hHHHHHHHHHHHHHHhcCCChHhHHhhccH
Confidence            77776      44 778899999999999977766555554444


No 59
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=97.84  E-value=6.1e-09  Score=106.37  Aligned_cols=350  Identities=19%  Similarity=0.201  Sum_probs=191.7  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+..++.+.++.++..++.++.+++.........+...++++.++.++. ..+..++..++.+|.+++... ....
T Consensus        44 ~~i~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~-~~~~  122 (457)
T 1XM9_A           44 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKE  122 (457)
T ss_dssp             THHHHHHHHTTSSCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTCHHHHHHHHTTCCCHHHHHHHHHHHHHHHTSS-STHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHhhCCHHHHHHHHhcChHHHHHHHhhhCCCHHHHHHHHHHHHHHhCCH-HHHH
Confidence            34566677777777888999999999988654443444445567778888876 556778888999999887632 2222


Q NP_000290.2     324 ETRRQNGIREAVSLL----------------RRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSG  385 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL----------------~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~  385 (747)
                      .+. .++++.+..++                . ..++.++..++.++.+++........+..  ++++.|+.++......
T Consensus       123 ~~~-~~~~~~l~~~l~~~~~~~~~~~~~~~~~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~  200 (457)
T 1XM9_A          123 ELI-ADALPVLADRVIIPFSGWCDGNSNMSRE-VVDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAA  200 (457)
T ss_dssp             HHH-HHHHHHCCCCCCHHHHTCC----------CCCHHHHHHHHHHHHHHTTSHHHHHHHTTSTTHHHHHHHHHHHHHHH
T ss_pred             HHH-cchHHHHHHHhccccCCCCCCCCCcccc-cCCHHHHHHHHHHHHHHccChHHHHHHHhcccHHHHHHHHHHHhhhc
Confidence            222 45677777776                3 44667888899999999876544444443  5677777777642211


Q NP_000290.2     386 WCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLA-------LVPQR-ATSSRVNLSSAD-------------------  438 (747)
Q Consensus       386 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-------~~~~~-~~~~~~~~~~~~-------------------  438 (747)
                                ...++++...+..+|..-....+...       ..+.+ ...+.......+                   
T Consensus       201 ----------~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  270 (457)
T 1XM9_A          201 ----------SRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEE  270 (457)
T ss_dssp             ----------TCTTCTTHHHHHHHHHHHTTTHHHHSCCHHHHHHHTC----------------------------CCCCC
T ss_pred             ----------CcCCHHHHHHHHHHHHHHhcccccCCCcchhhhhhcccccccccccccccCcccchhccccccCCCCccc
Confidence                      11234444455544433211000000       00000 000000000000                   


Q NP_000290.2     439 ---AGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFS  515 (747)
Q Consensus       439 ---~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  515 (747)
                         .+++.+.. .+.+..|...+...     -+....+.+...|.|+...-                             
T Consensus       271 ~~~~~~~~~~~-~~~~~~l~~~l~~~-----~~~~~~~~a~~~L~~l~~~~-----------------------------  315 (457)
T 1XM9_A          271 TNPKGSGWLYH-SDAIRTYLNLMGKS-----KKDATLEACAGALQNLTASK-----------------------------  315 (457)
T ss_dssp             SSCCGGGGGGS-HHHHHHHHHHHHHC-----CCHHHHHHHHHHHHHHTTCS-----------------------------
T ss_pred             CCCchhHHhhc-hhHHHHHHHHhccC-----CCHHHHHHHHHHHHHHHhcc-----------------------------
Confidence               00000000 01111111111000     00000011111111111000                             


Q NP_000290.2     516 NKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEK  595 (747)
Q Consensus       516 ~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~g  595 (747)
                                     +.... ......+.+.++++.|+.++. +.++.++..++.+|.+++....      ....+ ..+
T Consensus       316 ---------------~~~~~-~~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~------~~~~~-~~~  371 (457)
T 1XM9_A          316 ---------------GLMSS-GMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMSRHPL------LHRVM-GNQ  371 (457)
T ss_dssp             ---------------SSHHH-HHHHCCCCCSCCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSGG------GHHHH-HHH
T ss_pred             ---------------ccccC-CcchhhhhhcchHHHHHHHHh-cCCHHHHHHHHHHHHHHhcCHH------HHHHH-Hcc
Confidence                           00000 001123456778899999998 4677888999999999986432      12232 345


Q NP_000290.2     596 GLPQIARLLQSG------NSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRN  667 (747)
Q Consensus       596 iI~~Ll~LL~s~------d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsn  667 (747)
                      +++.|+.++...      ++.++..++.+|.+|+.. +.. ..+...++++.|..++...     .++.++..++.+|.+
T Consensus       372 ~~~~l~~~l~~~~~~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~ll~~~-----~~~~v~~~a~~~L~~  446 (457)
T 1XM9_A          372 VFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS-----ASPKAAEAARLLLSD  446 (457)
T ss_dssp             THHHHHHTTTSCCSCSTTHHHHHHHHHHHHHHHHTTCTHHHHHHCCHHHHHHHHHHHHCT-----TCHHHHHHHHHHHHT
T ss_pred             cHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHhcCHHHHHHHHhccHHHHHHHHHhCC-----CCHHHHHHHHHHHHH
Confidence            788888888765      678899999999999854 333 3445567788888887652     267888999999999


Q NP_000290.2     668 LMAS  671 (747)
Q Consensus       668 La~~  671 (747)
                      |+..
T Consensus       447 l~~~  450 (457)
T 1XM9_A          447 MWSS  450 (457)
T ss_dssp             TSSS
T ss_pred             Hhhc
Confidence            8864


No 60
>4I2Z_A Protein UNC-45, Heat shock protein; chaperone, myosin folding, protein filaments; 2.9A {Caenorhabditis elegans}
Probab=97.84  E-value=7.3e-09  Score=122.51  Aligned_cols=69  Identities=14%  Similarity=0.132  Sum_probs=41.5  Template_Neff=8.600

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      ++.|+.++...+..++..+..++..+... ......+...+.++.|+.++.+.++..+..++.+|..++.
T Consensus       648 ~~~Lv~ll~~~s~~~r~~~~~~l~~l~~~-~~~R~~iv~~G~v~~Ll~ll~~~~~~~~~~Aa~ALa~l~~  716 (961)
T 4I2Z_A          648 VPACVAVSKTESKNALELIARSLLAFAEY-EDLRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA  716 (961)
T ss_dssp             HHHHHHTCCCSCSHHHHHHHHHHHTTSCS-STTHHHHTTTTHHHHHHHHHHHSCTHHHHHHHHHHHHHSS
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHhCC-HHHHHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc
Confidence            44555555555566677777777777643 3344445555666777777665555566666666665543


No 61
>6SWY_5 Vacuolar import and degradation protein; Suppressed, Suppreseed, LIGASE; 3.2A { Saccharomyces cerevisiae YJM1133}
Probab=97.83  E-value=7.4e-09  Score=121.91  Aligned_cols=402  Identities=11%  Similarity=0.070  Sum_probs=223.3  Template_Neff=8.700

Q NP_000290.2     240 IECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFR  317 (747)
Q Consensus       240 ~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~  317 (747)
                      +...+.++..+..++...+..++..++.+|..++..... ....+...++++.++.++...+ +. +..++.+|..++..
T Consensus       281 l~~~~~~~~~L~~Ll~s~~~~lr~~Al~~L~~L~~~~~~~~~~~~~~~g~l~~Li~lL~~~~~~~-~~~al~~L~~L~~~  359 (921)
T 6SWY_5          281 LRNDATFKMFVLGLLKSNDVNIRCVALKFLLQPYFTEDKKWEDTRTLEKILPYLVKSFNYDPLPW-WFDPFDMLDSLIVL  359 (921)
T ss_dssp             STTCSHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHSSSTTSCHHHHHHHHHHHHHTTSCSSCCT-TCCHHHHHHHHHHH
T ss_pred             hhcccchHHHHHHHhcCCCHHHHHHHHHHHHHHHhCCCCchhhHHHHccHHHHHHHHcCCCCCch-hchHHHHHHHHHHH
Confidence            334455566666777777788899999999998865332 1233344567888888887654 44 77888888888762


Q NP_000290.2     318 S-------TTNKLETRRQNGIRE-AVSLLRRTG--------NAEIQKQLTGLLWNLSSTDEL-KEELIA--DALPVLADR  378 (747)
Q Consensus       318 ~-------~~~~~~ll~~~IL~~-Ll~lL~ss~--------d~eVr~~AL~aLsnLas~~~~-~~~Lve--giLe~Lv~L  378 (747)
                      .       ......+...+.+.. +..++. ..        +..++..++.++..++..... ...+..  ++++.|+.+
T Consensus       360 ~~~~~~~~~~~~~~l~~~g~i~~lL~~ll~-~~~~~~~~~~~~~v~~~al~~L~~L~~~~e~~r~~l~~~~~~l~~L~~l  438 (921)
T 6SWY_5          360 YNEITPMNNPVLTTLAHTNVIFCILSRFAQ-CLSLPQHNEATLKTTTKFIKICASFAASDEKYRLLLLNDTLLLNHLEYG  438 (921)
T ss_dssp             HHHHSTTCCHHHHHHHHTTHHHHHHHHHHH-HHTCSSCCHHHHHHHHHHHHHHHHHHTSCHHHHHHHHTTSSHHHHHHHH
T ss_pred             hcccCCCCCHHHHHHHHcChHHHHHHHHHH-hcCCccCCcCCHHHHHHHHHHHHHHhCCCHHHHHHHhccccHHHHHHHH
Confidence            1       111122223455565 555554 33        566778888999888875432 232333  567777777


Q NP_000290.2     379 VIIPF-------SGWC------DGNSNMS-REVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAG-RQT  443 (747)
Q Consensus       379 L~~~~-------~~~~------~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~  443 (747)
                      +....       +.|-      .+....+ ....|+++...+..+|+.                     ++..... ++.
T Consensus       439 L~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~d~~v~~~al~~L~~---------------------Ls~~~~~lr~~  497 (921)
T 6SWY_5          439 LESHITLIQDFISLKDEIKETTTESHSMCLPPIYDHDFVAAWLLLLKS---------------------FSRSVSALRTT  497 (921)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHTTTCTTCCCCCTTHHHHHHHHHHHHH---------------------HTTCHHCCCCC
T ss_pred             HHhhHHHHHHHHhccHHHHhcccccccCCCCCCCCHHHHHHHHHHHHH---------------------HhCCHHHHHHH
Confidence            76220       0000      0000000 011124444444444432                     1111111 111


Q NP_000290.2     444 MRNYSGLIDSLMAYVQNCVA-ASRC----------DDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTG  512 (747)
Q Consensus       444 ~~~~~~~~~~~~~~~~~~~~-~~~~----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  512 (747)
                      +.. .|++..|...++.... ...|          +..-...+...|.|++..-                          
T Consensus       498 l~~-~g~i~~Ll~lL~~~~~~~~~~~~~~~~~~~~~~~v~~~al~aL~nL~~~~--------------------------  550 (921)
T 6SWY_5          498 LKR-NKIAQLLLQILSKTYTLTKECYFAGQDFMKPEIMIMGITLGSICNFVVEF--------------------------  550 (921)
T ss_dssp             SCC-HHHHHHHHHHHHHHHHHHHHCGGGCSTTTHHHHHHHHHHHHHHHHHTSSS--------------------------
T ss_pred             HHH-CChHHHHHHHHHhhccchHhhhcCCcccccccHHHHHHHHHHHHHHHccC--------------------------
Confidence            111 2444444444432200 0000          1111122222222222110                          


Q NP_000290.2     513 CFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS----------------------KKDATLEACAG  570 (747)
Q Consensus       513 ~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss----------------------~d~eVr~~AL~  570 (747)
                                              ......+++.|+++.|+.++...                      .+..++..+++
T Consensus       551 ------------------------~~~~~~l~~~gii~~L~~lL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~al~  606 (921)
T 6SWY_5          551 ------------------------SNLQSFMLRNGIIDIIEKMLTDPLFNSKKAWDDNEDERRIALQGIPVHEVKANSLW  606 (921)
T ss_dssp             ------------------------CTTHHHHHHTTHHHHHHHHHTSTTTCTTSCCCSSCHHHHHHSTTSCCSHHHHHHHH
T ss_pred             ------------------------chHHHHHHHCCHHHHHHHHhcChhhccccccCCCccHHHHHhcCCCCHHHHHHHHH
Confidence                                    01112234556677777766521                      45677889999


Q NP_000290.2     571 ALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL-----------L-HRVMG-----  633 (747)
Q Consensus       571 aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-----------~-~~ll~-----  633 (747)
                      +|.+++.....   . ....+...++++.|+.++.+.++.++..++++|.+++....           . ...+.     
T Consensus       607 aL~nL~~~~~~---~-~~~~l~~~~~l~~Ll~lL~~~~~~v~~~a~~~L~nL~~~~~~~~~~ll~~~~~~~~l~~~~~~~  682 (921)
T 6SWY_5          607 VLRHLMYNCQN---E-EKFQLLAKIPMNLILDFINDPCWAVQAQCFQLLRNLTCNSRKIVNILLEKFKDVEYKIDPQTGN  682 (921)
T ss_dssp             HHHHHTTTCCH---H-HHHHHHHHSCHHHHHTTTTCSSHHHHHHHHHHHHHHHTTCSHHHHHHHHTC-------------
T ss_pred             HHHHHHcCCCH---H-HHHHHHhcCCHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHhhcccceeeCcCCCC
Confidence            99999875331   0 12344566888999999988888999999999999987632           1 12222     


Q NP_000290.2     634 ------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS-SMLNNIINLCR---------SSAS  697 (747)
Q Consensus       634 ------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~-giL~~Ll~LL~---------s~~d  697 (747)
                            .++++.|+..+.........+..++..++++|.+++...+.....+++. ++++.|..++.         .. +
T Consensus       683 ~~~~~~~~ll~~L~~~L~~~~~~~~~~~~v~~~al~~L~nLa~~~~~~~~~ii~~~~il~~L~~lL~~~~~~~~~~~~-~  761 (921)
T 6SWY_5          683 KISIGSTYLFEFLAKKMRLLNPLDTQQKKAMEGILYIIVNLAAVNENKKQLVIEQDEILNIMSEILVETTTDSSSYGN-D  761 (921)
T ss_dssp             ------CCHHHHHHHHHHHSCTTSHHHHHHHHHHHHHHHHHHTSCHHHHHHHHHCHHHHHHHHHHHTCCSSCCSSGGG-C
T ss_pred             ccccccccHHHHHHHHHhccCCCchhcHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHHHHHHHHHHhcCCCccccCC-C
Confidence                  3567777777765200000156788999999999997654544444544 67888888887         44 6


Q NP_000290.2     698 PKAAEAARLLLSDMWSSKELQGV  720 (747)
Q Consensus       698 ~eVr~aAL~aLsnL~~~~~~~~~  720 (747)
                      +.++..++++|.+|+...+.+..
T Consensus       762 ~~v~~~al~aL~nL~~~~~~~~~  784 (921)
T 6SWY_5          762 SNLKLACLWVLNNLLWNSSVSHY  784 (921)
T ss_dssp             HHHHHHHHHHHHHHHCC------
T ss_pred             HHHHHHHHHHHHHHHcCCCcccc
Confidence            78999999999999987655433


No 62
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=97.83  E-value=6.6e-09  Score=103.80  Aligned_cols=297  Identities=19%  Similarity=0.226  Sum_probs=179.9  Template_Neff=12.000

Q NP_000290.2     236 CSEDIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-----------NQNVQ  304 (747)
Q Consensus       236 ~~~~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-----------d~eVr  304 (747)
                      |.+-++-.+.........+.+.++.++..++.+|.++... ......+...++++.+..++...           +..++
T Consensus        23 ~~~~~~~~~~~~~~~~~~l~~~~~~~~~~a~~~L~~l~~~-~~~~~~~~~~~~~~~L~~~l~~~~~~~~~~~~~~~~~~~  101 (354)
T 5IZ8_A           23 CWEWQEAHEPGMDQDKNPMPAPVEHQICPAVCVLMKLSFD-EEHRHAMNELGGLQAIAELLQVDCEMYGLTNDHYSITLR  101 (354)
T ss_dssp             HHHHHHHSCSSCCCCSSCCCCGGGGTHHHHHHHHHHHHTS-HHHHHHHHHTTHHHHHHHHHHHHHHHHCSCCCHHHHHHH
T ss_pred             HHHHHHhcCCCCCCCCCCCCCCchHhHHHHHHHHHHccCC-HHHHHHHHHcCHHHHHHHHHHhhHHHhCCCCCCCCHHHH
Confidence            4443343344444444555667778888899999988765 33333344456777777777643           67788


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKLETRR-QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST--DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~~ll~-~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~--~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.++.+++.........+.. .++++.+..++. ..++.++..++.++.+++..  ......+.. ++++.|+.++.
T Consensus       102 ~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  180 (354)
T 5IZ8_A          102 RYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLK-SESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECAL  180 (354)
T ss_dssp             HHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGG-SSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHH
Confidence            88999999987644333333333 467777888886 55678888999999999874  222333444 77777877776


Q NP_000290.2     381 IPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSA-DAGRQTMRNYSGLIDSLMAYVQ  459 (747)
Q Consensus       381 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  459 (747)
                      ..               .++++...+..+|..                     +... +..++.+..-.|.++.|...+.
T Consensus       181 ~~---------------~~~~~~~~a~~~L~~---------------------l~~~~~~~~~~~~~~~~~~~~l~~~l~  224 (354)
T 5IZ8_A          181 EV---------------KKESTLKSVLSALWN---------------------LSAHCTENKADICAVDGALAFLVGTLT  224 (354)
T ss_dssp             HC---------------CSHHHHHHHHHHHHH---------------------HHTSCHHHHHHHHTSTTHHHHHHHHTT
T ss_pred             hc---------------CCHHHHHHHHHHHHH---------------------HHcCChHhHHHHHhhccHHHHHHHHHh
Confidence            42               133443333333322                     1111 1122222221345555555444


Q NP_000290.2     460 NCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKG  539 (747)
Q Consensus       460 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~  539 (747)
                      ...  ...+..-.+.+..+|.+++..+.                                               .+...
T Consensus       225 ~~~--~~~~~~~~~~~~~~L~~l~~~~~-----------------------------------------------~~~~~  255 (354)
T 5IZ8_A          225 YRS--QTNTLAIIESGGGILRNVSSLIA-----------------------------------------------TNEDH  255 (354)
T ss_dssp             CCC--TTSCCHHHHHHHHHHHHHHHHHH-----------------------------------------------TCHHH
T ss_pred             hcC--CCCcHHHHHHHHHHHHHHHHHhc-----------------------------------------------CCHHH
Confidence            210  01113334555555666541100                                               01112


Q NP_000290.2     540 SGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLL  619 (747)
Q Consensus       540 ~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aL  619 (747)
                      ...+.+.++++.|+.++. ..++.++..++.+|.+++...+.     ....+.+.++++.|+.++.+.++.++..++.+|
T Consensus       256 ~~~l~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L  329 (354)
T 5IZ8_A          256 RQILRENNCLQTLLQHLK-SHSLTIVSNACGTLWNLSARNPK-----DQEALWDMGAVSMLKNLIHSKHKMIAMGSAAAL  329 (354)
T ss_dssp             HHHHHTTTHHHHHHHTTT-CSCHHHHHHHHHHHHHHSSSCHH-----HHHHHHTTTHHHHHHHHSSCSSHHHHHHHHHHH
T ss_pred             HHHHHHCCHHHHHHHHhh-cCCHHHHHHHHHHHHHHHccCHH-----HHHHHHhCCHHHHHHHHHhccCHHHHHHHHHHH
Confidence            223356678888888887 46777888999999999874332     233445678899999999888888999999999


Q NP_000290.2     620 SNMSRH  625 (747)
Q Consensus       620 snLa~~  625 (747)
                      .+++..
T Consensus       330 ~~l~~~  335 (354)
T 5IZ8_A          330 RNLMAN  335 (354)
T ss_dssp             HHHHTT
T ss_pred             HHHHcc
Confidence            999876


No 63
>3IFQ_A plakoglobin, E-cadherin; armadillo repeat, Cardiomyopathy, Cell adhesion; HET: SO4; 2.8A {Homo sapiens}
Probab=97.83  E-value=6.4e-09  Score=107.67  Aligned_cols=374  Identities=16%  Similarity=0.150  Sum_probs=218.5  Template_Neff=13.100

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..+++.+...+.+.++.++..++.++..+..............++++.+...+. ..++.++..++.++..+..... ..
T Consensus        18 ~~~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~-~~   96 (553)
T 3IFQ_A           18 TRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHRE-GL   96 (553)
T ss_dssp             HHTHHHHHHHHTCSCHHHHHHHHHHHHHHTTSHHHHHHHHTCHHHHHHHHHHHTTCCCHHHHHHHHHHHHHHTTSHH-HH
T ss_pred             cCcHHHHHHHhcCCCHHHHHHHHHHHHHHhCCHHHHHHHhcCchHHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHH-HH
Confidence            345666777777777888888999998887653221111112356666777666 4556778888888888775432 22


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...+.++.+...+. +.++.++..++.++..++..... ...+.. ++++.|..++...                ++
T Consensus        97 ~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~  159 (553)
T 3IFQ_A           97 LAIFKSGGIPALVRMLS-SPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKN----------------NP  159 (553)
T ss_dssp             HHHHHTTHHHHHHHGGG-CCCHHHHHHHHHHHHHHHHHCTTHHHHHHHTTGGGGTGGGGGSS----------------CH
T ss_pred             HHHHHcCcHHHHHHHcc-CCCHHHHHHHHHHHHHHhcCChHHHHHHHhcCHHHHHHHHHhcC----------------CH
Confidence            22333456777777776 55677888888888888764332 222222 6666676666531                33


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..+|..-...      .+              ..+..+ --.++++.|...+...     .+......++..|.
T Consensus       160 ~~~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~  213 (553)
T 3IFQ_A          160 KFLAITTDCLQLLAYG------NQ--------------ESKLII-LANGGPQALVQIMRNY-----SYEKLLWTTSRVLK  213 (553)
T ss_dssp             HHHHHHHHHHHHHHTT------CH--------------HHHHHH-HHTTHHHHHHHHHHHC-----CCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHcC------CH--------------HHHHHH-HHCCHHHHHHHHHhcC-----CcHHHHHHHHHHHH
Confidence            4444444433321100      00              000000 0113344443333210     01111222223333


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      +++..-                                                   .....+.+.++++.++.++. +.
T Consensus       214 ~l~~~~---------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  241 (553)
T 3IFQ_A          214 VLSVCP---------------------------------------------------SNKPAIVEAGGMQALGKHLT-SN  241 (553)
T ss_dssp             HHTTST---------------------------------------------------THHHHHHHTTHHHHHHGGGG-SS
T ss_pred             HHhCCc---------------------------------------------------chHHHHHHCchHHHHHHHHh-cC
Confidence            322100                                                   00112234567888888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++.....      ...  ..++++.+..++.+.++.++..++.+|.+++... .. ..+...++++
T Consensus       242 ~~~~~~~a~~~l~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  313 (553)
T 3IFQ_A          242 SPRLVQNCLWTLRNLSDVATK------QEG--LESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVE  313 (553)
T ss_dssp             CHHHHHHHHHHHHHHHTTCTT------CSC--CHHHHHHHHTTTTCCCHHHHHHHHHHHHHHTTTCHHHHHHHTTTTHHH
T ss_pred             CHHHHHHHHHHHHHhCChhHH------HHH--HHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHccHHH
Confidence            778888999999999865321      111  2467888888888888889999999999998763 22 2334455777


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ---LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e---~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+...    ..++.++..++.+|.+++...+.   ....+...+.++.+..++.+..++.++..++.+|.+++...
T Consensus       314 ~l~~~l~~~----~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~  389 (553)
T 3IFQ_A          314 ALIHAILRA----GDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCP  389 (553)
T ss_dssp             HHHHHHHHH----TTCHHHHHHHHHHHHHHTSSSTTHHHHHHHHHTTTHHHHHHHGGGCTTCHHHHHHHHHHHHHHTTSG
T ss_pred             HHHHHHHHc----CCChHhHHHHHHHHHHHhcCCChHHHHHHHHHHcchHHHHHHHHcCCCChHHHHHHHHHHHHHhcCc
Confidence            777766531    02567888999999999875332   11223344567888888876523788899999999998876


Q NP_000290.2     716 ELQGVLRQQG  725 (747)
Q Consensus       716 ~~~~~~~~~~  725 (747)
                      +....+...|
T Consensus       390 ~~~~~~~~~~  399 (553)
T 3IFQ_A          390 ANHAPLQEAA  399 (553)
T ss_dssp             GGHHHHHHTT
T ss_pred             ccHHHHHHcc
Confidence            6554444333


No 64
>4I2W_A Protein UNC-45, Heat shock 70; chaperone, myosin folding, protein filaments; 3.6A {Caenorhabditis elegans}
Probab=97.83  E-value=7.9e-09  Score=122.23  Aligned_cols=70  Identities=14%  Similarity=0.133  Sum_probs=42.2  Template_Neff=8.600

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      +++.|+.++...+..++..+..++..+... ......+...+.++.|+.++.+.++..+..++.+|..++.
T Consensus       647 ~~~~Lv~ll~~~s~~~r~~~~~~l~~l~~~-~~~R~~ivq~g~~~~Ll~ll~~~~~~~~~~Aa~ALa~l~~  716 (961)
T 4I2W_A          647 AVPACVAVSKTESKNALELIARSLLAFAEY-EDLRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA  716 (961)
T ss_dssp             SSHHHHHTTCCCCSHHHHHHHHHHHTTSSS-STTTTTTTTSSHHHHHHHHHHHSTTHHHHHHHHHHHTTSS
T ss_pred             CHHHHHHHhcCCCHHHHHHHHHHHHHHhCC-HHHHHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc
Confidence            344555555555566677777777777643 3344445555666777776665555566666666666653


No 65
>4R10_A Protein humpback-2, Cadherin-related hmr-1; armadillo repeat, cell adhesion, phosphorylation; HET: SEP; 2.3A {Caenorhabditis elegans}
Probab=97.79  E-value=8.7e-09  Score=108.23  Aligned_cols=398  Identities=14%  Similarity=0.146  Sum_probs=205.5  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+...++.++..++.++..++.........+
T Consensus       115 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  194 (572)
T 4R10_A          115 GLAEIIRMLYDSLESVVHYAVTTLRNLLMHVSDSRAQARALNAVEALTPHLHKTNPKLLAQVADGLYFLLIDDAPSKITF  194 (572)
T ss_dssp             THHHHHHGGGCSCHHHHHHHHHHHHHHHHHCTHHHHHHHHTTHHHHHGGGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHHhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHHhcCCHHHHHHHHHHHHHHHCCChHHHHHH
Confidence            34555666666677888889999998866443333334444677778888877778888899999988875443333333


Q NP_000290.2     326 RRQNGIREAVSLLRR-TGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~s-s~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...+++..+...+.. ..+..++..++.++..++........+.. ++++.++..+...               .++++.
T Consensus       195 ~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~~~~~  259 (572)
T 4R10_A          195 LSLLGPQILVSILREYSDHRKLIYTVVRCIRSLSVCPSNKPALISLGCLPALYVELCTA---------------KDERSQ  259 (572)
T ss_dssp             HHTTHHHHHHHHHHHCTTCHHHHHHHHHHHHHHTTSTTHHHHHHHTTHHHHHHHHHTTC---------------CSHHHH
T ss_pred             HhccHHHHHHHHHHHCCCCHHHHHHHHHHHHHHhcCcchHHHHHhCCcHHHHHHHHhcC---------------CCHHHH
Confidence            344566667766641 23456778888888888765443333333 5555554433321               123333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..                     ....++.+   .+++..+...++.      -+..-...+...|.++.
T Consensus       260 ~~a~~~l~~l~~---------------------~~~~~~~~---~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  309 (572)
T 4R10_A          260 TAILVAMRNLSD---------------------SATNEENL---TQLIIKLLEIIRV------ANDGMTACACGTLSNLT  309 (572)
T ss_dssp             HHHHHHHHHHGG---------------------GCTTCSCC---HHHHHHHHHHHHH------CCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHcC---------------------ChHHHHHH---HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHH
Confidence            333333322110                     00011111   1123333322211      12222333444444444


Q NP_000290.2     484 YRLDAEVP---------TRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLN  554 (747)
Q Consensus       484 ~~~~~~~~---------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~  554 (747)
                      ..-+....         .-...+.....+.........+..+-..    .        ...+......+...++++.++.
T Consensus       310 ~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~----~--------~~~~~~~~~~~~~~~~~~~l~~  377 (572)
T 4R10_A          310 CNNTRNKQTVCSHGGIDALVTAIRRLPEVEEVTEPALCALRHCTA----R--------HSLAEEAQSELRFCQAFPVILD  377 (572)
T ss_dssp             SSCHHHHHHHHHTTHHHHHHHHHHHSTTCHHHHHHHHHHHHHHTS----S--------STTHHHHHHHHHHTTHHHHHHH
T ss_pred             cCCHHHHHHHHHCcHHHHHHHHHHhCCCcHHHHHHHHHHHHHhhc----c--------CCCcHHHHHHHhhCChHHHHHH
Confidence            32111000         0000000000000000000000000000    0        0000111122245567788888


Q NP_000290.2     555 LMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK------EKGLPQIARLLQS----------------GNSDVV  612 (747)
Q Consensus       555 LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie------~giI~~Ll~LL~s----------------~d~eVr  612 (747)
                      ++. +.+..++..++.+|.+++.....      ...+.+      .++++.+..++..                .++.++
T Consensus       378 ~l~-~~~~~v~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~  450 (572)
T 4R10_A          378 QLE-TLRTPVIKAALGVIRNSALLQTN------LIELTQEQTANGHTAVSLTMDILRRAITAIEENPDIAVDGVPMWGVI  450 (572)
T ss_dssp             HHT-TCCHHHHHHHHHHHHHHHTSHHH------HHHHHHCCCTTCCCHHHHHHHHHHHHHHHHHHCTTCEETTEEHHHHH
T ss_pred             HHh-cCCHHHHHHHHHHHHHHhccchh------HHHHHHHhhhCCCCcHHHHHHHHHHHHHhcccCcchhccCccHHHHH
Confidence            887 36667777888888888764221      111122      2344555555432                234566


Q NP_000290.2     613 RSGASLLSNMSRHPLLH-RVMGN----------QVFPEVTRLL------TSHTGNTSNSEDILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~~-~ll~~----------giI~~Ll~LL------~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~  675 (747)
                      ..++.+|.+++...... .+...          ++++.+..++      ..      .++.++..++.+|.+++.. +..
T Consensus       451 ~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~------~~~~v~~~a~~~l~~l~~~-~~~  523 (572)
T 4R10_A          451 EGAVSALHQLANHPAVAAACCDDIGQVGNPECPPFLDLLHRLLAHPRLGSM------DDEVLEREILGLLYQLSKR-PDG  523 (572)
T ss_dssp             HHHHHHHHHHTTSHHHHHHHHHCCCCTTCTTSCCHHHHHHHHHHSHHHHSC------SCSHHHHHHHHHHHHHTSS-HHH
T ss_pred             HHHHHHHHHHhCCHHHHHHHhccccCCCCCCCccHHHHHHHHHhCcccCCC------ChHHHHHHHHHHHHHHhcC-Cch
Confidence            77788888877653221 11111          4666666666      33      3677888888888888865 344


Q NP_000290.2     676 AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       676 ~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ...+...++++.|..++.+. ++.++..++.+|.++....
T Consensus       524 ~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~L~~l~~~~  562 (572)
T 4R10_A          524 ARAVESTGVSALLMESRGSQ-YKSVVTYANGVLSNLKRGD  562 (572)
T ss_dssp             HHHHHTTTTHHHHHHHTTCS-CHHHHHHHHHHHHHHHHHH
T ss_pred             hhHHHHcChhhHHhHhhCCC-CchHHHHHHHHHHHhhcCC
Confidence            44455566778888888766 7788888888888887654


No 66
>5T94_B Guanine nucleotide exchange factor SRM1; Nuclear Import, Importin alpha, RCC1; 2.631A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.78  E-value=9.3e-09  Score=108.50  Aligned_cols=159  Identities=19%  Similarity=0.225  Sum_probs=117.7  Template_Neff=12.200

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ...++++.|+.++. ..++.++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++
T Consensus       254 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~  327 (542)
T 5T94_B          254 VVSQALPTLAKLIY-SMDTETLVDACWAISYLSDGPQE-----AIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIV  327 (542)
T ss_dssp             HHGGGHHHHHHHTT-CCCHHHHHHHHHHHHHHSSSSHH-----HHHHHHHTTCHHHHHHTTSCSSHHHHHHHHHHHHHHT
T ss_pred             HHhcHHHHHHHHHh-cCCHHHHHHHHHHHHHHcCCCHH-----HHHHHHhCCHHHHHHHHhcCCCHHHHHHHHHHHHHHH
Confidence            34556777777777 46677888899999988865332     2333345668888888888888889999999999998


Q NP_000290.2     624 RHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .... . ......++++.|..++.+      .++.++..++++|.+++...+.....+...++++.|+.++.+. ++.++
T Consensus       328 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  400 (542)
T 5T94_B          328 TGNDLQTQVVINAGVLPALRLLLSS------PKENIKKEACWTISNITAGNTEQIQAVIDANLIPPLVKLLEVA-EYKTK  400 (542)
T ss_dssp             TSCHHHHHHHHHTTHHHHHHHHTTC------SSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHHHS-CHHHH
T ss_pred             cCCHHHHHHHHHCChHHHHHHHhhC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCchHHHHHHHHcC-CHHHH
Confidence            7632 2 233445678888888866      3678889999999999876555555566666788888888766 77888


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       401 ~~a~~~l~~l~~~~  414 (542)
T 5T94_B          401 KEACWAISNASSGG  414 (542)
T ss_dssp             HHHHHHHHHHHGGG
T ss_pred             HHHHHHHHHHHcCC
Confidence            99999999888764


No 67
>6KBN_A Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.78  E-value=9.2e-09  Score=107.80  Aligned_cols=358  Identities=22%  Similarity=0.258  Sum_probs=207.0  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+.......    ....+++.+...+.+.++.++..++.++..++..... ...
T Consensus        32 ~~i~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~-~~~  106 (563)
T 6KBN_A           32 GPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLL  106 (563)
T ss_dssp             CTHHHHHHHHTTCCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHHSSCCHHHHHHHHHHHHHHTTSHHH-HHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHhhhhHHH----hccchHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcch-HHH
Confidence            34566666676677788888888888876532211    2245666777777777777888888888887754322 222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ....+.++.+...+. ..++.++..++.++..++........+.. ++++.|..++...                ++++-
T Consensus       107 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  169 (563)
T 6KBN_A          107 IVEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQ  169 (563)
T ss_dssp             HHHHTCHHHHHHHHH-SSCHHHHHHHHHHHHHTTCSHHHHHHHHTTTTHHHHHHHTTCS----------------SHHHH
T ss_pred             HHHCCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhCCCchHHHHHhcChHHHHHHHccCC----------------CHHHH
Confidence            233355666777665 45667788888888888765433222222 5566666655421                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     .....+..+. ..++++.+...++.      -+..-...+...|.++.
T Consensus       170 ~~a~~~l~~l~---------------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  221 (563)
T 6KBN_A          170 RNATGALLNMT---------------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIA  221 (563)
T ss_dssp             HHHHHHHHHTT---------------------SSHHHHHHHH-TTTCHHHHHHHTTC------SSHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHh---------------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHh
Confidence            33333322110                     0000111111 12344444444331      11222223333333332


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                . .........++++.+..++. +.++.
T Consensus       222 ~~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~  251 (563)
T 6KBN_A          222 VDEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSR  251 (563)
T ss_dssp             TSHH------------------------------------------------H-HHHHHHHCSSHHHHHHHHTT-CSCHH
T ss_pred             CCHH------------------------------------------------H-HHHHHhhchhHHHHHHHHhc-CCCHH
Confidence            2000                                                0 00000012346777888887 46777


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTR  642 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~  642 (747)
                      ++..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..
T Consensus       252 ~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~  325 (563)
T 6KBN_A          252 VKCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVR  325 (563)
T ss_dssp             HHHHHHHHHHHHTTSHHH------HHHHHHTTCHHHHHHHHTCSCHHHHHHHHHHHHHHHTSGGGHHHHHHTTCHHHHHT
T ss_pred             HHHHHHHHHHHHhCChhH------HHHHHHCCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHH
Confidence            888999999998875321      22334567888888888888888999999999999876433 23344567788888


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++...     .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++..++.++..+...
T Consensus       326 ~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~  391 (563)
T 6KBN_A          326 LLDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALA  391 (563)
T ss_dssp             TTTCT-----TCHHHHHHHHHHHHHHHHHCSTTHHHHHHTTHHHHHHHHHTSS-CHHHHHHHHHHHHHHTTC
T ss_pred             HhCCC-----CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHhCC-CHHHHHHHHHHHHHHhcC
Confidence            87652     2478888999999999876444444455555677777776654 556666666666655543


No 68
>6KBN_C Vacuolar protein 8, Autophagy-related protein; Armadillo repeats, complex, PROTEIN BINDING-PROTEIN; 3.2A {Saccharomyces cerevisiae}
Probab=97.78  E-value=9.2e-09  Score=107.80  Aligned_cols=358  Identities=22%  Similarity=0.258  Sum_probs=206.7  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+.......    ....+++.+...+.+.++.++..++.++..++..... ...
T Consensus        32 ~~i~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~----~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~-~~~  106 (563)
T 6KBN_C           32 GPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQ----VSREVLEPILILLQSQDPQIQVAACAALGNLAVNNEN-KLL  106 (563)
T ss_dssp             -CHHHHHHHHTTCCHHHHHHHHHHHHHHHHHCCCC----CCHHHHHHHHHHHCCSCHHHHHHHHHHHHHHTTSHHH-HHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHhhhhHHH----hccchHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcch-HHH
Confidence            34566666676677788888888888876532211    2245666777777777777888888888887754322 222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ....+.++.+...+. ..++.++..++.++..++........+.. ++++.|..++...                ++++-
T Consensus       107 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v~  169 (563)
T 6KBN_C          107 IVEMGGLEPLINQMM-GDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSK----------------HIRVQ  169 (563)
T ss_dssp             HHHTSCSHHHHHHTT-SSCHHHHHHHHHHHHHTTCSHHHHHHHHGGGCHHHHHHHTTSS----------------SHHHH
T ss_pred             HHHCCcHHHHHHHhh-CCCHHHHHHHHHHHHHHhCCCchHHHHHhcChHHHHHHHccCC----------------CHHHH
Confidence            233355666777665 45667788888888888765433222222 5566666655421                23333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-.                     .....+..+. ..++++.+...++.      -+..-...+...|.++.
T Consensus       170 ~~a~~~l~~l~---------------------~~~~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  221 (563)
T 6KBN_C          170 RNATGALLNMT---------------------HSEENRKELV-NAGAVPVLVSLLSS------TDPDVQYYCTTALSNIA  221 (563)
T ss_dssp             HHHHHHHHHHT---------------------SSHHHHHHHH-TTTCHHHHHHHTTC------SSHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHh---------------------CCHHHHHHHH-HCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHh
Confidence            33333322110                     0000111111 12344444444331      11222223333333332


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+                                                . .........++++.+..++. +.++.
T Consensus       222 ~~~~------------------------------------------------~-~~~~~~~~~~~~~~l~~~l~-~~~~~  251 (563)
T 6KBN_C          222 VDEA------------------------------------------------N-RKKLAQTEPRLVSKLVSLMD-SPSSR  251 (563)
T ss_dssp             TSHH------------------------------------------------H-HHHHHHSSTTHHHHHHHHTT-CSSHH
T ss_pred             CCHH------------------------------------------------H-HHHHHhhchhHHHHHHHHhc-CCCHH
Confidence            2000                                                0 00000012346777888887 46777


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTR  642 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~  642 (747)
                      ++..++.+|.+++.....      ...+...++++.+..++.+.++.++..++.+|.+++..... ......++++.+..
T Consensus       252 ~~~~a~~~l~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~  325 (563)
T 6KBN_C          252 VKCQATLALRNLASDTSY------QLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVR  325 (563)
T ss_dssp             HHHHHHHHHHHHTTSHHH------HHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHTSGGGHHHHHHTTCHHHHHH
T ss_pred             HHHHHHHHHHHHhCChhH------HHHHHHCCcHHHHHHHHhCCCHHHHHHHHHHHHHHhcCcchHHHHHHCCcHHHHHH
Confidence            888999999998875321      22334567888888888888888999999999999876433 23344567788888


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++...     .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++..++.++..+...
T Consensus       326 ~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~l~~l~~~  391 (563)
T 6KBN_C          326 LLDYK-----DSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDS-PVSVQSEISACFAILALA  391 (563)
T ss_dssp             HTTCS-----SCHHHHHHHHHHHHHHHHHCSTTSHHHHTTCHHHHHHHHHTSS-CHHHHHHHHHHHHHHTTC
T ss_pred             HhCCC-----CCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHhCC-CHHHHHHHHHHHHHHhcC
Confidence            87652     2478888999999999876444444455555677777776654 556666666666655543


No 69
>2Z6G_A B-catenin; Full-Length, Beta-Catenin, CELL ADHESION; 3.4A {Danio rerio}
Probab=97.75  E-value=1.2e-08  Score=115.80  Aligned_cols=373  Identities=17%  Similarity=0.153  Sum_probs=224.6  Template_Neff=10.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..+++.+...+.+.++.++..++.+|..+..............+++..+...+.+ .+..++..++.+|..+..... ..
T Consensus       149 ~~~l~~L~~lL~~~~~~vr~~a~~~L~~l~~~~~~~~~~~~~~~~i~~L~~~L~~~~~~~vr~~a~~~L~~l~~~~~-~~  227 (780)
T 2Z6G_A          149 TRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTSGTLHNLSHHRE-GL  227 (780)
T ss_pred             cChHHHHHHHccCCCHHHHHHHHHHHHHHhCChHHHHHHHhCCCHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCHH-HH
Confidence            3566777777877788899999999998876532221111122466777777765 677888889999988875422 22


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI-A-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv-e-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+..++. ..++.++..++.+|..++.........+ . ++++.|+.++..+                ++
T Consensus       228 ~~~~~~~~i~~L~~lL~-~~~~~v~~~al~~L~~l~~~~~~~~~~~~~~~~~~~L~~lL~~~----------------~~  290 (780)
T 2Z6G_A          228 LAIFKSGGIPALVNMLG-SPVDSVLFHAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT----------------NV  290 (780)
T ss_pred             HHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCC----------------CH
Confidence            22333567778888886 5567788899999998886533222222 2 6677777766531                34


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++-..+..+|..-....                    ...+..+. ..+++..|...+...     .+.+-.+.++.+|.
T Consensus       291 ~v~~~a~~~L~~l~~~~--------------------~~~~~~~~-~~~~~~~L~~~l~~~-----~~~~v~~~a~~~L~  344 (780)
T 2Z6G_A          291 KFLAITTDCLQILAYGN--------------------QESKLIIL-ASGGPQALVNIMRTY-----TYEKLLWTTSRVLK  344 (780)
T ss_pred             HHHHHHHHHHHHHHcCC--------------------HHHHHHHH-HCCcHHHHHHHhCCC-----CCHHHHHHHHHHHH
Confidence            44455555554311100                    00011110 123444444333221     01112222222332


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      +++...                                                   .....+.+.++++.|+.++. +.
T Consensus       345 ~l~~~~---------------------------------------------------~~~~~~~~~~~l~~L~~~l~-~~  372 (780)
T 2Z6G_A          345 VLSVCS---------------------------------------------------SNKPAIVEAGGMQALGLHLT-DP  372 (780)
T ss_pred             HHhCCH---------------------------------------------------HHHHHHHHCCHHHHHHHHcc-CC
Confidence            222100                                                   00112245667888888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~  638 (747)
                      +..++..++.+|.+++.....      ..  ...++++.|+.++.+.+..++..++.+|.+++.. ... ..+...++++
T Consensus       373 ~~~v~~~al~~L~~l~~~~~~------~~--~~~~~l~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~l~  444 (780)
T 2Z6G_A          373 SQRLVQNCLWTLRNLSDAATK------QE--GMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIE  444 (780)
T ss_pred             CHHHHHHHHHHHHHHhcCCCC------HH--HHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHH
Confidence            778888999999999864321      11  1256788888888888888999999999999876 222 2334456777


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL---AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~---~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .|+..+...    ..++.++..++.+|.+++...+..   ...+...++++.|+.++....+..++..++.+|.+++...
T Consensus       445 ~L~~~l~~~----~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~l~~~~  520 (780)
T 2Z6G_A          445 ALVRTVLRA----GDREDITEPAICALRHLTSRHQDAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCP  520 (780)
T ss_pred             HHHHHHhcC----CCCHHHHHHHHHHHHHHHcCCccHHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCH
Confidence            777766521    035678899999999998653221   2223334567888888875435678899999999988776


Q NP_000290.2     716 ELQGVLRQQ  724 (747)
Q Consensus       716 ~~~~~~~~~  724 (747)
                      +....+...
T Consensus       521 ~~~~~~~~~  529 (780)
T 2Z6G_A          521 ANHAPLREQ  529 (780)
T ss_pred             HHHHHHHhC
Confidence            654444333


No 70
>5EWP_B Uncharacterized protein; translocation and attachment of rhoptries; 1.8A {Plasmodium falciparum Santa Lucia}
Probab=97.73  E-value=1.3e-08  Score=96.81  Aligned_cols=118  Identities=16%  Similarity=0.189  Sum_probs=81.2  Template_Neff=11.800

Q NP_000290.2     263 AIGAYYIQHTCFQ--DESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRR  340 (747)
Q Consensus       263 ~sAL~aLsnLs~~--~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~s  340 (747)
                      ..++.++.++...  .......+...+.++.+..++...+..++..++.++.+++.........+...+.++.++.++. 
T Consensus        60 ~~~~~~l~~l~~~~~~~~~~~~~~~~g~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~-  138 (252)
T 5EWP_B           60 ALSATQLAILASKENEPHYKDAIREANGIAVFINLLKSHELDRVHAAVVALSFLSVDNVKNCICMFESGALPYLISGMK-  138 (252)
T ss_dssp             HHHHHHHHHHHTCTTCTHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTCHHHHHHHTT-
T ss_pred             HHHHHHHHHHhcCCCCHHHHHHHHHcccHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhh-
Confidence            4677788777754  2333344445567788888887777778889999999988654444444444567777888776 


Q NP_000290.2     341 TGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       341 s~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      ..++.++..++.++.+++.. ......+.+ ++++.|+.++..
T Consensus       139 ~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  181 (252)
T 5EWP_B          139 SNIDGMKAACAQTCRNIFVLDKKYKKEFLKLGGITQLVNLLEL  181 (252)
T ss_dssp             CSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHTTSC
T ss_pred             CCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHHHHhcC
Confidence            55678889999999999864 333334444 777888877764


No 71
>5XGC_A Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF, ONCOPROTEIN; 2.1A {Homo sapiens}
Probab=97.72  E-value=1.3e-08  Score=103.51  Aligned_cols=358  Identities=19%  Similarity=0.180  Sum_probs=198.3  Template_Neff=13.200

Q NP_000290.2     257 QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVS  336 (747)
Q Consensus       257 sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~  336 (747)
                      .++.++..++.++..+.... .....+...++++.+...+.+.++.++..++.++..++...+.....+...++++.+..
T Consensus         5 ~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~   83 (503)
T 5XGC_A            5 SQSSCKAKVANIIAEVAKNE-FMRIPCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVK   83 (503)
T ss_dssp             -------------------C-CCCCCSSCHHHHHHHHHHTTCSCHHHHHHHHHHHHHSCCCSHHHHHHHHHTTHHHHHHH
T ss_pred             chHHHHHHHHHHHHHHhcCh-hhhhhhhhcCcHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCchHHHHHHHCChHHHHHH
Confidence            34567777888888887642 22333444567788888888778888999999999988654333333444567778888


Q NP_000290.2     337 LLRRT-GNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRL  414 (747)
Q Consensus       337 lL~ss-~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  414 (747)
                      .+... .++.++..++.++..++........+.. ++++.|+.++....               ++++-..+..+|..- 
T Consensus        84 ~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~~---------------~~~~~~~a~~~l~~l-  147 (503)
T 5XGC_A           84 LLGIHCQNAALTEMCLVAFGNLAELESSKEQFASTNIAEELVKLFKKQI---------------EHDKREMIFEVLAPL-  147 (503)
T ss_dssp             HHHHTTTCHHHHHHHHHHHHHHTTSHHHHHHHTTTTHHHHHHHHHHHCC---------------CHHHHHHHHHHHHHH-
T ss_pred             HHhccCCCHHHHHHHHHHHHHHHccHHHHHHHhcCCHHHHHHHHHHhcC---------------ChhHHHHHHHHHHHH-
Confidence            87622 3677888999999998876443333333 67777777776421               233333333333211 


Q NP_000290.2     415 GMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRY  494 (747)
Q Consensus       415 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  494 (747)
                                          ...+..+..+. -.|.+..++..+...      ++.........+.+...          
T Consensus       148 --------------------~~~~~~~~~~~-~~~~~~~l~~~l~~~------~~~~~~~~~~~l~~~~~----------  190 (503)
T 5XGC_A          148 --------------------AENDAIKLQLV-EAGLVECLLEIVQQK------VDSDKEDDITELKTGSD----------  190 (503)
T ss_dssp             --------------------TTSHHHHHHHH-HTTHHHHHHHHHHHH------TTCCCHHHHHHHHHHHH----------
T ss_pred             --------------------HcCHHHHHHHH-HCCHHHHHHHHHHhc------CCCCCHHHHHHHHHHHH----------
Confidence                                11111111111 123444444433221      11111111111100000          


Q NP_000290.2     495 RQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSD---AIRTYLNLMGKSKKDATLEACAGA  571 (747)
Q Consensus       495 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G---~I~~LL~LL~ss~d~eVr~~AL~a  571 (747)
                                        .+.+-    ...         .+.   ...+...+   .++.++.++. +.++.++..++.+
T Consensus       191 ------------------~~~~~----~~~---------~~~---~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~  235 (503)
T 5XGC_A          191 ------------------LMVLL----LLG---------DES---MQKLFEGGKGSVFQRVLSWIP-SNNHQLQLAGALA  235 (503)
T ss_dssp             ------------------HHHHH----TTS---------HHH---HHHHHGGGTCHHHHHHHHHTT-SSCHHHHHHHHHH
T ss_pred             ------------------HHHHH----HhC---------Cch---HHHHHhcCcccHHHHHHHHcc-CCCHHHHHHHHHH
Confidence                              00000    000         000   01112222   6777888887 4677888899999


Q NP_000290.2     572 LQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ----SGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTS  646 (747)
Q Consensus       572 L~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~----s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s  646 (747)
                      |.+++.....      ...+.+.++++.|+.++.    +.+..++..++.+|.+++..... ..+...++++.+..++.+
T Consensus       236 L~~l~~~~~~------~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~  309 (503)
T 5XGC_A          236 IANFARNDAN------CIHMVDNGIVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKS  309 (503)
T ss_dssp             HHHHCSSHHH------HHHHHHTTHHHHHHHHHHTTTTTCCHHHHHHHHHHHHHHTCSHHHHHHHHHHTHHHHHHTTTTC
T ss_pred             HHHHHCChhH------HHHHHHCCHHHHHHHHHHhccccCCHHHHHHHHHHHHHhcCCHHHHHHHHHcCHHHHHHHHHcC
Confidence            9999874321      333456688888988887    56788899999999999876433 333445678888888876


Q NP_000290.2     647 HTGNTSNSEDILSSACYTVRNLMASQPQLAKQYF-SSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       647 ~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lv-e~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                            .++.++..++++|.+++...+.....+. ..++++.++.++.+.....++..++.+|.+++...
T Consensus       310 ------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~  373 (503)
T 5XGC_A          310 ------EMPPVQFKLLGTLRMLIDAQAEAAEQLGKNVKLVERLVEWCEAKDHAGVMGESNRLLSALIRHS  373 (503)
T ss_dssp             ------CCHHHHHHHHHHHHHHTTTCHHHHHHHHTCHHHHHHHHHHHTCTTCHHHHHHHHHHHHHHHHHH
T ss_pred             ------CCHHHHHHHHHHHHHHHccCHHHHHHHccccchHHHHHHHHccCCccchHHHHHHHHHHHHHHc
Confidence                  3678899999999999875433333332 24567788888776523378888999998886544


No 72
>6BW9_A Importin subunit alpha-3, Protein W; Complex, Hendra virus, Importin, Karyopherin; 1.6A {Homo sapiens}
Probab=97.70  E-value=1.6e-08  Score=102.40  Aligned_cols=367  Identities=16%  Similarity=0.162  Sum_probs=222.4  Template_Neff=12.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ...++.+...+.+.++.++..++.++..+...... ....+...++++.+...+. ..++.++..++.++..++......
T Consensus         8 ~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~   87 (459)
T 6BW9_A            8 NTSLEAIVQNASSDNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQ   87 (459)
T ss_dssp             --CHHHHHHHHTCSSHHHHHHHHHHHHHHHHSSSSCCHHHHHHTTHHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHH
T ss_pred             ccchHHHHHhccccCHHHHHHHHHHHHHHhcCCCCCCHHHHHHCChHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHH
Confidence            34556667777777788899999999888764321 1122333456777777776 456778888999998887654433


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+...+. +.++.++..++.++..++... .....+.. ++++.++.++...               .+
T Consensus        88 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~  151 (459)
T 6BW9_A           88 TQAVVQSNAVPLFLRLLH-SPHQNVCEQAVWALGNIIGDGPQCRDYVISLGVVKPLLSFISPS---------------IP  151 (459)
T ss_dssp             HHHHHHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHTCSTT---------------SC
T ss_pred             HHHHhhCCHHHHHHHHhc-CCChHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHhccCCC---------------CC
Confidence            333334457777888776 556788889999999887652 22222333 5666666666421               12


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++-..+..++..-                     ..............+++..+...+..      .+..-...+...|
T Consensus       152 ~~~~~~a~~~l~~l---------------------~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l  204 (459)
T 6BW9_A          152 ITFLRNVTWVMVNL---------------------CRHKDPPPPMETIQEILPALCVLIHH------TDVNILVDTVWAL  204 (459)
T ss_dssp             HHHHHHHHHHHHHH---------------------HCCCSSCCCHHHHHHHHHHHHHHTTC------CCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH---------------------hcCCCCCCCHHHHHHHHHHHHHHHhc------CCHHHHHHHHHHH
Confidence            33333333332211                     10000001111223344444433321      1112222223233


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++...-                                                  ......+.+.++++.++.++. +
T Consensus       205 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  233 (459)
T 6BW9_A          205 SYLTDAG--------------------------------------------------NEQIQMVIDSGIVPHLVPLLS-H  233 (459)
T ss_dssp             HHHHTSC--------------------------------------------------HHHHHHHHHTTCHHHHGGGGG-C
T ss_pred             HHHhhcC--------------------------------------------------hHHHHHHHhCChHHHHHHHcC-C
Confidence            3322100                                                  001112244567788888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++...+.     ....+.+.++++.+..++.+.++.++..++.+|.+++... .. ......+++
T Consensus       234 ~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~  308 (459)
T 6BW9_A          234 QEVKVQTAALRAVGNIVTGTDE-----QTQVVLNCDALSHFPALLTHPKEKINKEAVWFLSNITAGNQQQVQAVIDANLV  308 (459)
T ss_dssp             SSHHHHHHHHHHHHHHTTSCHH-----HHHHHHTTTGGGGCHHHHTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCH
T ss_pred             CCHHHHHHHHHHHHHHHcCCHH-----HHHHHhcccchhcHHHHhhCCCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHH
Confidence            6778888999999999875332     2233344578888888888888889999999999998662 22 233445677


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQ-PQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.+..++.+      .++.++..++.+|.+++... ......+.+.++++.|..++.+. ++.++..++.+|.+++...+
T Consensus       309 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~a~~~l~~l~~~~~  381 (459)
T 6BW9_A          309 PMIIHLLDK------GDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPPFCNLLTVK-DAQVVQVVLDGLSNILKMAE  381 (459)
T ss_dssp             HHHHHHHHH------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHHHGGGGCS-CHHHHHHHHHHHHHHHHHCT
T ss_pred             HHHHHHHHh------CCHHHHHHHHHHHHHHHHhCCHHHHHHHHHCCcHHHHHHhcCCC-CHHHHHHHHHHHHHHHHHhH
Confidence            888888776      36778899999999998532 22333444456788888888766 77889999999999876544


No 73
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=97.66  E-value=2e-08  Score=101.26  Aligned_cols=364  Identities=17%  Similarity=0.188  Sum_probs=216.7  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.++..+. ..++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        57 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  136 (466)
T 5D5K_C           57 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  136 (466)
T ss_dssp             HHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhhCCCChHHHHHHHHHHHHHcCCChHHHHHHhccchHHHHHHHhcCCCCcHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665 345678888889998887654433334444567778888888777888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. ..+..     ++..++.++..++..........  .++++.+..++..                
T Consensus       137 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  199 (466)
T 5D5K_C          137 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  199 (466)
T ss_dssp             HHHTTCHHHHHHTTC-SSCGGGSCHHHHHHHHHHHHHHSCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHhh-CCCcccccHHHHHHHHHHHHHHHcCCCCCCChHHHHHHHHHHHHHHcC----------------
Confidence            334456677777775 33333     77788888888876433222221  2455666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..++..-....      +              .....+ --.+++..|...+..      .+..-...+..
T Consensus       200 ~~~~~~~~a~~~l~~l~~~~------~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  252 (466)
T 5D5K_C          200 NDPEVLADSCWAISYLTDGP------N--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  252 (466)
T ss_dssp             SCHHHHHHHHHHHHHHTSSC------H--------------HHHHHH-HTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhcCC------c--------------hHHHHH-HHCChHHHHHHHhcC------CCchHHHHHHH
Confidence            13444444444443211100      0              000000 012233333333221      11112222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++....                                                  ......+.+.++++.++.++.
T Consensus       253 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  282 (466)
T 5D5K_C          253 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  282 (466)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHccChhHhHHHHhh
Confidence            333332100                                                  001112245567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       283 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  356 (466)
T 5D5K_C          283 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  356 (466)
T ss_dssp             -CSSHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899988888888999999999999875 2 22 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .......+.+.++++.+..++.+. ++.++..++.++
T Consensus       357 ~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  429 (466)
T 5D5K_C          357 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  429 (466)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHTTCHHHHHHHHHHTTHHHHHHHGGGCS-SHHHHHHHHHHH
T ss_pred             CcHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhCCCHHHHHHHHHcCHHHHHHHHHhCC-cHHHHHHHHHHH
Confidence            577788888776      3678889999999999862      122333344456778888888766 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      .+++...+
T Consensus       430 ~~l~~~~~  437 (466)
T 5D5K_C          430 EKYFSVEE  437 (466)
T ss_dssp             HHHC----
T ss_pred             HHhccCCc
Confidence            99887543


No 74
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=97.63  E-value=2.4e-08  Score=100.65  Aligned_cols=364  Identities=17%  Similarity=0.187  Sum_probs=219.0  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.++..+. ..++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        57 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  136 (466)
T 4UAF_B           57 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  136 (466)
T ss_pred             cHHHHHHHhhCCCChHHHHHHHHHHHHHhcCChHHHHHHHccChHHHHHHHhcCCCCCHHHHHHHHHHHHhcCCHHHHHH
Confidence            4555666665 345678888888998887654433334444567778888888777888999999999988654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       137 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  199 (466)
T 4UAF_B          137 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  199 (466)
T ss_pred             HHHCCcHHHHHHHhh-CCCcccccHHHHHHHHHHHHHHHcCCCCCCChhHHHHHHHHHHHHHcC----------------
Confidence            334456677777775 33333     77788888888876433222221  2555666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .|+++...+..++..-...      .+              .....+ --.+++..|...+..      .+..-...+..
T Consensus       200 ~~~~~~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  252 (466)
T 4UAF_B          200 NDPEVLADSCWAISYLTDG------PN--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  252 (466)
T ss_pred             CCHHHHHHHHHHHHHHhcC------Cc--------------HHHHHH-HHCChHHHHHHHhcC------CChhHHHHHHH
Confidence            1344544444444321100      00              000000 012233333333221      11112222233


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++....                                                  ......+.+.++++.+..++.
T Consensus       253 ~l~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  282 (466)
T 4UAF_B          253 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  282 (466)
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHhccCHHHHHHHHhc
Confidence            333332100                                                  001112245567888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...
T Consensus       283 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  356 (466)
T 4UAF_B          283 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  356 (466)
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999999875332     233334557888899998888888999999999999875 2 22 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.++
T Consensus       357 ~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  429 (466)
T 4UAF_B          357 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  429 (466)
T ss_pred             CcHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhCCChHHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            577788888776      3678889999999999862      122333344456778888888766 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      .+++...+
T Consensus       430 ~~l~~~~~  437 (466)
T 4UAF_B          430 EKYFSVEE  437 (466)
T ss_pred             HHHccCCc
Confidence            99887543


No 75
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=97.63  E-value=2.7e-08  Score=108.38  Aligned_cols=364  Identities=16%  Similarity=0.179  Sum_probs=198.9  Template_Neff=11.000

Q NP_000290.2     263 AIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG  342 (747)
Q Consensus       263 ~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~  342 (747)
                      ..++.+|..+....+.  ...+..+.++.++.++...++.++..++.+|..++.........+...++++.|+.++. ..
T Consensus        26 ~~~l~~L~~l~~~~~~--~~~~~~~~l~~li~~L~~~~~~v~~~a~~~L~~L~~~~~~~~~~~~~~g~i~~Lv~lL~-~~  102 (584)
T 3L6X_A           26 RGSLASLDSLRKGGPP--PPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLD-HP  102 (584)
T ss_dssp             --------------CC--CCCCCCCCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHGGG-CS
T ss_pred             cCchHHHHHHhcCCCC--CCcccCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCCcHHHHHHHhh-CC
Confidence            3445555555443221  11233467778888887777888999999999988544444444455567888888887 56


Q NP_000290.2     343 NAEIQKQLTGLLWNLSS--TDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMREL  419 (747)
Q Consensus       343 d~eVr~~AL~aLsnLas--~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  419 (747)
                      ++.++..++.+|.+++.  .......+.. ++++.|+.+|...               .|+++-..+.++|..       
T Consensus       103 ~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~L~~ll~~~---------------~~~~v~~~a~~~L~~-------  160 (584)
T 3L6X_A          103 KKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKA---------------RDMDLTEVITGTLWN-------  160 (584)
T ss_dssp             SHHHHHHHHHHHHHHTSSSCHHHHHHHHHTTHHHHHHHHHHHC---------------CSHHHHHHHHHHHHH-------
T ss_pred             CHHHHHHHHHHHHHHhcCCCHHHHHHHHcCChHHHHHHHHHHc---------------CCHHHHHHHHHHHHH-------
Confidence            67899999999999987  3344444444 7888888888731               134444455555432       


Q NP_000290.2     420 LALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEY  499 (747)
Q Consensus       420 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  499 (747)
                                    |++.+..+..+...  .+..|...+........   ...+               +..    .+. 
T Consensus       161 --------------L~~~~~~~~~l~~~--~l~~L~~~l~~~~~~~~---~~~~---------------~~~----~~~-  201 (584)
T 3L6X_A          161 --------------LSSHDSIKMEIVDH--ALHALTDEVIIPHSGWE---REPN---------------EDC----KPR-  201 (584)
T ss_dssp             --------------HTTSGGGHHHHHHH--THHHCCCCCCHHHHCCC---------------------------------
T ss_pred             --------------HhcCHHHHHHHHHH--HHHHHHHhccccCCCCC---CCCC---------------cCC----CCc-
Confidence                          11111122222211  22233322221110000   0000               000    000 


Q NP_000290.2     500 NARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYH-SDAIRTYLNLMGK-----SKKDATLEACAGALQ  573 (747)
Q Consensus       500 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve-~G~I~~LL~LL~s-----s~d~eVr~~AL~aL~  573 (747)
                      ...+........+|+.|-+.               .+......+.+ .++++.|+.++..     ..+..++..++.+|.
T Consensus       202 ~~~~~~v~~~a~~~L~~l~~---------------~~~~~~~~l~~~~g~v~~L~~~l~~~~~~~~~~~~~~~~a~~~L~  266 (584)
T 3L6X_A          202 HIEWESVLTNTAGCLRNVSS---------------ERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLR  266 (584)
T ss_dssp             CCCCHHHHHHHHHHHHHHTS---------------SCHHHHHHHHHSTTHHHHHHHHHHHHHHTTCCSCHHHHHHHHHHH
T ss_pred             ccChHHHHHHHHHHHHHHhc---------------CCHHHHHHHHhCCCHHHHHHHHHHHHhcCCCCChHHHHHHHHHHH
Confidence            00000111112222222211               00011111223 4667888887762     125667778888888


Q NP_000290.2     574 NLTASKGLMS--------------------SGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRH-----PL  627 (747)
Q Consensus       574 nLs~~s~~~s--------------------~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~-----~e  627 (747)
                      +++.......                    .......+.+.++++.|+.++... ++.++..++.+|.+|+..     ..
T Consensus       267 ~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~~~~~~~~~a~~~L~~L~~~~~~~~~~  346 (584)
T 3L6X_A          267 NLSYQVHREIPQAERYQEAAPNVANNTGTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRY  346 (584)
T ss_dssp             HHHTTHHHHSTTCCC--------------CCCCGGGGGGSHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHSSCSHHHHH
T ss_pred             HHHhhhhccChhHHHHHHhcCcCCCCCCCCChhhhhHhhChhHHHHHHHHHHcCCCHHHHHHHHHHHHHHhCCCccCCHH
Confidence            8876421000                    000122334568888899988875 788999999999999874     22


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA-------SPK  699 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~-------d~e  699 (747)
                      . ..+...++++.|+.++..      .+..++..++++|.+|+.. +.....+. .++++.|+.++....       +..
T Consensus       347 ~~~~~~~~~~l~~L~~ll~~------~~~~v~~~a~~~L~~L~~~-~~~~~~l~-~~~l~~L~~~L~~~~~~~~~~~~~~  418 (584)
T 3L6X_A          347 IRSALRQEKALSAIADLLTN------EHERVVKAASGALRNLAVD-ARNKELIG-KHAIPNLVKNLPGGQQNSSWNFSED  418 (584)
T ss_dssp             HHHHHTSHHHHHHHHHGGGC------SCHHHHHHHHHHHHHHHTT-CSCHHHHH-HHHHHHHHHTSSSSSCSGGGTCCHH
T ss_pred             HHHHHHHcChHHHHHHHhcC------CCHHHHHHHHHHHHHHhcC-hHHHHHHH-cchHHHHHHcCCCCCCCCCcCCCHH
Confidence            2 233456788888888876      3678899999999999875 44444443 467888888776431       234


Q NP_000290.2     700 AAEAARLLLSDMWS  713 (747)
Q Consensus       700 Vr~aAL~aLsnL~~  713 (747)
                      ++..++.+|.+++.
T Consensus       419 ~~~~~l~~L~~l~~  432 (584)
T 3L6X_A          419 TVISILNTINEVIA  432 (584)
T ss_dssp             HHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHHHh
Confidence            46778888888773


No 76
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=97.60  E-value=2.9e-08  Score=98.47  Aligned_cols=367  Identities=14%  Similarity=0.181  Sum_probs=226.7  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..++.+...+.+.++.++..++..+..+...... ....+...++++.+...+. ..++.++..++.++..++.......
T Consensus         5 ~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~   84 (426)
T 4U5L_A            5 WSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQT   84 (426)
T ss_dssp             CCHHHHHHHHTSSCHHHHHHHHHHHHHHHHCSSCCCHHHHHHTTCHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHH
T ss_pred             ccHHHHHhhccCCCHHHHHHHHHHHHHHHhcCCCccHHHHHHcCcHHHHHHHhccCCChHHHHHHHHHHHHHhCCCHHHH
Confidence            4556667777777888889999999888764322 1222333456777777776 4456788889999988876544333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDP  400 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~  400 (747)
                      ..+...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.....           +..++
T Consensus        85 ~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~-----------~~~~~  152 (426)
T 4U5L_A           85 KAVVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDL-----------STLAC  152 (426)
T ss_dssp             HHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHHTCHHHHHHHHHTTCHHHHHHTTCSSCG-----------GGSCH
T ss_pred             HHHHhcCcHHHHHHHhc-CCChHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhCCCC-----------chhhH
Confidence            33344467777888776 5677888999999999887543 2223333 677777777764211           11122


Q NP_000290.2     401 EVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       401 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      ++...+..++..-                     ..............+++..+...++.      .+..-...+...|.
T Consensus       153 ~~~~~~~~~l~~l---------------------~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~  205 (426)
T 4U5L_A          153 GYLRNLTWTLSNL---------------------CRNKNPAPPLDAVEQILPTLVRLLHH------NDPEVLADSCWAIS  205 (426)
T ss_dssp             HHHHHHHHHHHHH---------------------TCCCSSCCCHHHHHHHHHHHHHHTTS------SCHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHH---------------------HcCCCCCCCccHHHHHHHHHHHHHhC------CCHHHHHHHHHHHH
Confidence            2333333222211                     11111111111113344444333321      11122222222232


Q NP_000290.2     481 NLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK  560 (747)
Q Consensus       481 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~  560 (747)
                      ++...-.                                                  .....+.+.++++.++.++. +.
T Consensus       206 ~l~~~~~--------------------------------------------------~~~~~~~~~~~~~~l~~~l~-~~  234 (426)
T 4U5L_A          206 YLTDGPN--------------------------------------------------ERIEMVVKKGVVPQLVKLLG-AT  234 (426)
T ss_dssp             HHTSSCH--------------------------------------------------HHHHHHHTTTCHHHHHHHHT-CS
T ss_pred             HHhhCCc--------------------------------------------------HHHHHHhhcChHHHHHHHhc-CC
Confidence            2221100                                                  00111234567888888887 46


Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~  638 (747)
                      ++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. +.. ..+...++++
T Consensus       235 ~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~  309 (426)
T 4U5L_A          235 ELPIVTPALRAIGNIVTGTDE-----QTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVP  309 (426)
T ss_dssp             CHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHH
T ss_pred             CccHHHHHHHHHHHHhcCCHH-----HHHHHhccchHHHHHHHhcCCChHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHH
Confidence            778888999999999875332     233334567888999999888889999999999999875 222 2334456778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      .+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++.
T Consensus       310 ~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~  378 (426)
T 4U5L_A          310 FLVGVLSK------ADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLSAK-DTKIIQVILDAISNIFQ  378 (426)
T ss_dssp             HHHHHHHS------SCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHHHHGGGSC-CHHHHHHHHHHHHHHHH
T ss_pred             HHHHHhcC------CCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhcCC-CHHHHHHHHHHHHHHHH
Confidence            88888876      3678889999999999874 233334455556788888888876 78899999999999976


No 77
>4MZ6_E Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin; ARM repeat, protein transport, Importin; 1.88A {Mus musculus}
Probab=97.58  E-value=3.4e-08  Score=101.56  Aligned_cols=364  Identities=17%  Similarity=0.184  Sum_probs=217.7  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+. ++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus       101 ~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  180 (509)
T 4MZ6_E          101 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  180 (509)
T ss_dssp             HHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHHHHHHHhcChHHHHHHHhcCCChhHHHHHHHHHHHHhCCCHHHHHH
Confidence            455566666543 3678888889988887654443334444567788888888777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       181 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  243 (509)
T 4MZ6_E          181 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  243 (509)
T ss_dssp             HHHTTCHHHHHHHTC-SSCGGGSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTC----------------
T ss_pred             HHHCCcHHHHHHHHh-CCChhhhhHHHHHHHHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHhC----------------
Confidence            334456677777775 33333     77788888888876432221111  2556666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .++++...+..++..-....      +              .....+ --.+++..|...++.      .+..-...+..
T Consensus       244 ~~~~v~~~a~~~l~~l~~~~------~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  296 (509)
T 4MZ6_E          244 NDPEVLADSCWAISYLTDGP------N--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  296 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTSSS------H--------------HHHHHH-HTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhcCC------h--------------HHHHHH-hhCChHHHHHHHhcC------CCcchHHHHHH
Confidence            13444444444443211100      0              000000 012233333333321      11112222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.++....                                                  ......+.+.++++.|..++.
T Consensus       297 ~L~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  326 (509)
T 4MZ6_E          297 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  326 (509)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHhCChHHHHHHHhh
Confidence            333322100                                                  001112245567788888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|+.++.+.++.++..++.+|.+++..  ... ..+...
T Consensus       327 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  400 (509)
T 4MZ6_E          327 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  400 (509)
T ss_dssp             -CSSHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999998875332     233334557888888888888888999999999999875  222 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.+|
T Consensus       401 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  473 (509)
T 4MZ6_E          401 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  473 (509)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHTTHHHHHHHHTTCS-SHHHHHHHHHHH
T ss_pred             CCHHHHHHHHhC------CCHHHHHHHHHHHHHHHHHHHHcCCCchHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            577888888776      3678888999999998862      123333344456788888888776 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      ..+....+
T Consensus       474 ~~l~~~~~  481 (509)
T 4MZ6_E          474 EKYFSVEE  481 (509)
T ss_dssp             HHHCC---
T ss_pred             HHHCCCCc
Confidence            99886543


No 78
>5UMZ_B Importin subunit alpha-1, TNRC6A; mRNA decay, miRNA ARM repeat; HET: GOL; 1.9A {Mus musculus}
Probab=97.58  E-value=3.4e-08  Score=101.56  Aligned_cols=364  Identities=17%  Similarity=0.184  Sum_probs=219.0  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+. ++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus       101 ~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  180 (509)
T 5UMZ_B          101 LIPKFVSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPHAHISEQAVWALGNIAGDGSAFRDL  180 (509)
T ss_dssp             CHHHHHHHHTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHHTCHHHHHH
T ss_pred             cHHHHHHHhcCCCChHHHHHHHHHHHHHhCCCHHHHHHHHhcChHHHHHHHhcCCChhHHHHHHHHHHHHhCCCHHHHHH
Confidence            455566666543 3678888889988887654443334444567788888888777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAE-----IQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~e-----Vr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      +...++++.+...+. .....     ++..++.++..++..........  .++++.+..++..                
T Consensus       181 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------  243 (509)
T 5UMZ_B          181 VIKHGAIDPLLALLA-VPDLSTLACGYLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHH----------------  243 (509)
T ss_dssp             HHHTTCHHHHHHHTC-SSCGGGSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTS----------------
T ss_pred             HHHCCcHHHHHHHHh-CCChhhhhHHHHHHHHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHhC----------------
Confidence            334456677777775 33333     77788888888876432221111  2556666666542                


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                      .++++...+..++..-....      +              .....+ --.+++..|...++.      .+..-...+..
T Consensus       244 ~~~~v~~~a~~~l~~l~~~~------~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~  296 (509)
T 5UMZ_B          244 NDPEVLADSCWAISYLTDGP------N--------------ERIEMV-VKKGVVPQLVKLLGA------TELPIVTPALR  296 (509)
T ss_dssp             SCHHHHHHHHHHHHHHTSSC------H--------------HHHHHH-HTTTCHHHHHHHHTC------SCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHhcCC------h--------------HHHHHH-hhCChHHHHHHHhcC------CCcchHHHHHH
Confidence            13444444444443211100      0              000000 012233333333321      11112222333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.++....                                                  ......+.+.++++.|..++.
T Consensus       297 ~L~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~  326 (509)
T 5UMZ_B          297 AIGNIVTGT--------------------------------------------------DEQTQKVIDAGALAVFPSLLT  326 (509)
T ss_dssp             HHHHHTTSC--------------------------------------------------HHHHHHHHHTTGGGGHHHHTT
T ss_pred             HHHHHhcCC--------------------------------------------------HHHHHHHHhCChHHHHHHHhh
Confidence            333322100                                                  001112245567788888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGN  634 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~  634 (747)
                       +.++.++..++.+|.+++...+.     ....+...++++.|+.++.+.++.++..++.+|.+++..  ... ..+...
T Consensus       327 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~  400 (509)
T 5UMZ_B          327 -NPKTNIQKEATWTMSNITAGRQD-----QIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHC  400 (509)
T ss_dssp             -CSSHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHHHHHT
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhC
Confidence             46778888999999998875332     233334557888888888888888999999999999875  222 233445


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS------QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~------s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                      ++++.+..++.+      .++.++..++.+|.+++..      .+.....+.+.++++.+..++.+. ++.++..++.+|
T Consensus       401 ~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l  473 (509)
T 5UMZ_B          401 GIIEPLMNLLSA------KDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIEALQRHE-NESVYKASLNLI  473 (509)
T ss_dssp             TCHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHTTHHHHHHHHHTCS-CHHHHHHHHHHH
T ss_pred             CCHHHHHHHHhC------CCHHHHHHHHHHHHHHHHHHHHcCCCchHHHHHHHcCHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence            577888888776      3678888999999998862      123333344456788888888776 788999999999


Q NP_000290.2     709 SDMWSSKE  716 (747)
Q Consensus       709 snL~~~~~  716 (747)
                      ..+....+
T Consensus       474 ~~l~~~~~  481 (509)
T 5UMZ_B          474 EKYFSVEE  481 (509)
T ss_dssp             HHHCCCCC
T ss_pred             HHHCCCCc
Confidence            99886543


No 79
>5ZHX_D Rap1 GTPase-GDP dissociation stimulator 1; armadillo GEF chaperone, ONCOPROTEIN; HET: FAR; 3.5A {Homo sapiens}
Probab=97.57  E-value=3.6e-08  Score=99.74  Aligned_cols=332  Identities=20%  Similarity=0.193  Sum_probs=197.3  Template_Neff=13.200

Q NP_000290.2     282 QVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTG--NAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       282 ~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~--d~eVr~~AL~aLsnLas  359 (747)
                      .+...++++.+...+.+.++.++..++.++..++...+.....+...++++.+...+. ..  ++.++..++.++..++.
T Consensus        13 ~l~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~-~~~~~~~v~~~a~~~l~~l~~   91 (487)
T 5ZHX_D           13 PCVDAGLISPLVQLLNSKDQEVLLQTGRALGNICYDSHSLQAQLINMGVIPTLVKLLG-IHCQNAALTEMCLVAFGNLAE   91 (487)
T ss_dssp             ---CHHHHHHHHHHTTCSCHHHHHHHHHHHHTTSTTCHHHHHHHHHTTCHHHHHHHHH-HTSSCSHHHHHHHHHHHHHTT
T ss_pred             HHhhcCcHHHHHHHHcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHHc-ccCCCHHHHHHHHHHHHHHHc
Confidence            3444567778888888778889999999999988654443334444567788888886 43  67888899999999887


Q NP_000290.2     360 TDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD  438 (747)
Q Consensus       360 ~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  438 (747)
                      .......+.. ++++.|+.++....               ++++-..+..+|..-                     ...+
T Consensus        92 ~~~~~~~~~~~~~~~~l~~~l~~~~---------------~~~~~~~a~~~l~~l---------------------~~~~  135 (487)
T 5ZHX_D           92 LESSKEQFASTNIAEELVKLFKKQI---------------EHDKREMIFEVLAPL---------------------AEND  135 (487)
T ss_dssp             SSHHHHHHHHTTHHHHHHHHHHHCC---------------SHHHHHHHHHHHHHH---------------------HTSH
T ss_pred             chhHHHHHhhCCHHHHHHHHHHhcc---------------ChHHHHHHHHHHHHH---------------------hcCH
Confidence            6443333333 67777777776431               333333333333211                     1111


Q NP_000290.2     439 AGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKS  518 (747)
Q Consensus       439 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  518 (747)
                      ..+..+. ..|.++.|+..+...      ++.........+.....                            .+.+..
T Consensus       136 ~~~~~~~-~~~~~~~l~~~l~~~------~~~~~~~~~~~l~~~~~----------------------------~~~~~~  180 (487)
T 5ZHX_D          136 AIKLQLV-EAGLVECLLEIVQQK------VDSDKEDDITELKTGSD----------------------------LMVLLL  180 (487)
T ss_dssp             HHHHHHH-HHTHHHHHHHHHHHT------SSCCCHHHHHHHHHHHH----------------------------HHHHHT
T ss_pred             HHHHHHH-HCCHHHHHHHHHHhc------CCCCCHHHHHHHHHHHH----------------------------HHHHHH
Confidence            1111111 123444444433321      11111111111110000                            000000


Q NP_000290.2     519 DKMMNNNYDCPLPEEETNPKGSGWLYHSD---AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEK  595 (747)
Q Consensus       519 ~~~~~~~~~~~~~~~~~ni~~~~~lve~G---~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~g  595 (747)
                          .+         .+.   ...+...+   .++.++.++. +.++.++..++.+|.+++....      ....+.+.+
T Consensus       181 ----~~---------~~~---~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~------~~~~~~~~~  237 (487)
T 5ZHX_D          181 ----LG---------DES---MQKLFEGGKGSVFQRVLSWIP-SNNHQLQLAGALAIANFARNDA------NCIHMVDNG  237 (487)
T ss_dssp             ----TS---------HHH---HHHHSSSSSSSHHHHHHTTTT-SSCHHHHHHHHHHHHHHCCSHH------HHHHHHTTT
T ss_pred             ----hc---------cHH---HHHHhhCCCchHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCch------HHHHHHhcC
Confidence                00         000   01112222   6777888887 4677888899999999987432      133345567


Q NP_000290.2     596 GLPQIARLLQ----SGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       596 iI~~Ll~LL~----s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      +++.++.++.    +.+..++..++.+|.+++..... ..+...++++.+..++.+      .++.++..++++|.+++.
T Consensus       238 ~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~  311 (487)
T 5ZHX_D          238 IVEKLMDLLDRHVEDGNVTVQHAALSALRNLAIPVINKAKMLSAGVTEAVLKFLKS------EMPPVQFKLLGTLRMLID  311 (487)
T ss_dssp             HHHHHHHHHHHTSSSSCHHHHHHHHHHHHHHTCSHHHHHHHHHHTHHHHHHTTSSC------CCHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHHHhcccCCCHHHHHHHHHHHHHhcCChhhHHHHHHcChHHHHHHHHhC------CCHHHHHHHHHHHHHHHh
Confidence            8888888887    56788899999999999876433 233445677888888876      367889999999999987


Q NP_000290.2     671 SQPQLAKQYF-SSSMLNNIINLCRSSASP-KAAEAARLLLSDMWSSK  715 (747)
Q Consensus       671 ~s~e~~~~Lv-e~giL~~Ll~LL~s~~d~-eVr~aAL~aLsnL~~~~  715 (747)
                      ..+.....+. ..++++.++.++.+. +. .++..++.+|.+++...
T Consensus       312 ~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~a~~~l~~l~~~~  357 (487)
T 5ZHX_D          312 AQAEAAEQLGKNVKLVERLVEWCEAK-DHAGVMGESNRLLSALIRHS  357 (487)
T ss_dssp             SCHHHHHHHHHCHHHHHHHHHHHTCC-SCCHHHHHHHHHHHHHHHHH
T ss_pred             hcHHHHHHhccccCHHHHHHHHHHhc-CchhhHHHHHHHHHHHHHHh
Confidence            5433333333 245678888888765 44 78888999999986544


No 80
>3NOW_A SD10334p; Armadillo Repeat, Hsp90, Myosin, Tetra-tricopeptide; 2.992A {Drosophila melanogaster}
Probab=97.57  E-value=3.6e-08  Score=107.84  Aligned_cols=135  Identities=17%  Similarity=0.118  Sum_probs=82.7  Template_Neff=12.800

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+... .... .....++++.+...+.+.+..++..++.++..+.........
T Consensus       289 ~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~-~~~~-~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~  366 (810)
T 3NOW_A          289 EGILQMILAMATTDDELQQRVACECLIAASSK-KDKA-KALCEQGVDILKRLYHSKNDGIRVRALVGLCKLGSYGGQDAA  366 (810)
T ss_dssp             TTHHHHHHHHHHSSCHHHHHHHHHHHHHHTTS-HHHH-HTTHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTTTTTTS
T ss_pred             cChHHHHHHHccCCCHHHHHHHHHHHHHHhCC-HHHH-HHHHhhhHHHHHHHhcCCCHHHHHHHHHHHHHHHccCCcccc
Confidence            44556666677777788899999999888764 2111 122235677777777777788888999999888764332111


Q NP_000290.2     324 ET-RRQNGIREAVSLLRR-----TGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVI  380 (747)
Q Consensus       324 ~l-l~~~IL~~Ll~lL~s-----s~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~  380 (747)
                      .. ...+.++.+...+..     +.++.++..++.++..++........+..  ++++.+..++.
T Consensus       367 ~~~~~~~~~~~l~~~l~~~l~~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  431 (810)
T 3NOW_A          367 IRPFGDGAALKLAEACRRFLIKPGKDKDIRRWAADGLAYLTLDAECKEKLIEDKASIHALMDLAR  431 (810)
T ss_dssp             CCSSTTTHHHHHHHHHHHHHHCSSCCSSHHHHHHHHHHHHTTSHHHHHHHHHCHHHHHHHHHHHH
T ss_pred             ccccCCCHHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHcCCHHHHHHHHhChHHHHHHHHHHc
Confidence            11 122344445544431     24567888889999888765433333322  46666666665


No 81
>4EV8_A Catenin beta-1; mouse catenin, CELL ADHESION; HET: URE; 1.9A {Mus musculus}
Probab=97.55  E-value=4.1e-08  Score=100.94  Aligned_cols=137  Identities=25%  Similarity=0.276  Sum_probs=86.1  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR--SPNQNVQQAAAGALRNLVFRSTTN-  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~--s~d~eVr~~AL~aLs~La~~~~~~-  321 (747)
                      .+++.+...+.+.+..++..++.++..+..........+...+.++.+...+.  ..++.++..++.++..++...... 
T Consensus       267 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~  346 (538)
T 4EV8_A          267 GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAE  346 (538)
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCCChH
Confidence            34555666666666778888888888886544433333344556667776665  445677888888888887644321 


Q NP_000290.2     322 --KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       322 --~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                        .......++++.+...+....++.++..++.++..++........+.. ++++.|..++..
T Consensus       347 ~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~  409 (538)
T 4EV8_A          347 MAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR  409 (538)
T ss_pred             HHHHHHHHCCHHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHHHHHcC
Confidence              112222356677777775223567888888999888875444433444 677777776653


No 82
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=97.54  E-value=4.4e-08  Score=95.72  Aligned_cols=161  Identities=21%  Similarity=0.247  Sum_probs=120.5  Template_Neff=12.500

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQIARLLQSGN----SDVVRSGASL  618 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~Ll~LL~s~d----~eVr~~AL~a  618 (747)
                      .+.++++.|+.++....++.++..++++|.+++...+.     ....+.. .++++.++.++...+    ..++..++++
T Consensus       162 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~  236 (339)
T 5Z8H_A          162 REVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGI  236 (339)
T ss_pred             HHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHHhcChHHHHHHHhcCCCCCCCHHHHHHHHHH
Confidence            45678888888887325677888899999999874332     2334455 688888988887543    6788889999


Q NP_000290.2     619 LSNMSR----HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       619 LsnLa~----~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~  693 (747)
                      |.+++.    .+.. ..+...++++.++.++..      .++.++..++++|.+++...+.....+.+.++++.|..++.
T Consensus       237 l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  310 (339)
T 5Z8H_A          237 LRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIH  310 (339)
T ss_pred             HHHHHHhhccCHHHHHHHHHCCHHHHHHHHHhC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhh
Confidence            999873    2222 233445678888888866      36778999999999999844666666667788999999988


Q NP_000290.2     694 SSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       694 s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +. ++.++..++.+|.+++...+
T Consensus       311 ~~-~~~v~~~a~~~l~~l~~~~~  332 (339)
T 5Z8H_A          311 SK-HKMIAMGSAAALRNLMANRP  332 (339)
T ss_pred             CC-CHHHHHHHHHHHHHHHcCCc
Confidence            76 78899999999999997654


No 83
>3SL9_B Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: GOL, EDO, PEG, IMD; 2.2A {Homo sapiens}
Probab=97.53  E-value=4.8e-08  Score=84.82  Aligned_cols=134  Identities=16%  Similarity=0.203  Sum_probs=89.6  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQL-GGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~-~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.++.++..... ....+... ++++.+..++.. .+..++..++.++.+++.. ....
T Consensus        13 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~   90 (167)
T 3SL9_B           13 RAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEA-SRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGL   90 (167)
T ss_pred             CcHHHHHHHhCCCCHHHHHHHHHHHHHHccCHH-HHHHHHhCCchHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHH
Confidence            345566666666677788889999998876543 22223332 377778887776 6677888899999888843 3333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      ..+...+.++.+..++. ..++.++..++.++.+++........++.  ++++.|+.++..
T Consensus        91 ~~~~~~~~i~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  150 (167)
T 3SL9_B           91 LAIFKSGGIPALVKMLG-SPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNK  150 (167)
T ss_pred             HHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHcCCHhHHHHHHHcCHHHHHHHHhcC
Confidence            33444567778888886 55677888899999998875443333332  677777777654


No 84
>4E4V_A Importin subunit alpha-2; armadillo repeat, karyopherin, importin, nuclear; HET: GOL, DTT; 2.5283A {Homo sapiens}
Probab=97.52  E-value=5e-08  Score=99.91  Aligned_cols=156  Identities=17%  Similarity=0.216  Sum_probs=117.7  Template_Neff=12.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.++.++. +.++.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++..
T Consensus       206 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~  279 (485)
T 4E4V_A          206 EQILPTLVRLLH-HDDPEVLADTCWAISYLTDGPNE-----RIGMVVKTGVVPQLVKLLGASELPIVTPALRAIGNIVTG  279 (485)
T ss_dssp             HHHHHHHHHHTT-SCCHHHHHHHHHHHHHHTSSCHH-----HHHHHHTTTCHHHHHHHHTCSCHHHHHHHHHHHHHHTTS
T ss_pred             hcHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCChH-----HhhHHhhCChHHHHHHHhcCCChHHHHHHHHHHHHHhcC
Confidence            356777888887 46778888999999998875332     223334567888899999888888999999999999876


Q NP_000290.2     626 P-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 ~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      . .. ......++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.|+.++.+. ++.++..
T Consensus       280 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~  352 (485)
T 4E4V_A          280 TDEQTQVVIDAGALAVFPSLLTN------PKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKA-DFKTQKE  352 (485)
T ss_dssp             CHHHHHHHHHTTGGGGHHHHHTC------SSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHS-CHHHHHH
T ss_pred             CHHHHHHHHhCChHHHHHHHhcC------CCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHHHHHHHHHhcC-CHHHHHH
Confidence            2 22 233445678888888876      3678899999999999876555555566667788888888766 7788889


Q NP_000290.2     704 ARLLLSDMWSS  714 (747)
Q Consensus       704 AL~aLsnL~~~  714 (747)
                      ++.+|.+++..
T Consensus       353 a~~~l~~l~~~  363 (485)
T 4E4V_A          353 AVWAVTNYTSG  363 (485)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHHhc
Confidence            99999888865


No 85
>1WA5_B GTP-BINDING NUCLEAR PROTEIN RAN, IMPORTIN; NUCLEAR TRANSPORT-COMPLEX, NUCLEAR TRANSPORT, EXPORTIN; HET: GTP; 2.0A {CANIS FAMILIARIS} SCOP: a.118.1.1
Probab=97.52  E-value=5.1e-08  Score=102.06  Aligned_cols=368  Identities=16%  Similarity=0.204  Sum_probs=223.8  Template_Neff=12.300

Q NP_000290.2     242 CSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDES-AKQQVYQLGGICKLVDLLRSPN-QNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       242 ~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~-~~~~li~~~IL~~Ll~lL~s~d-~eVr~~AL~aLs~La~~~~  319 (747)
                      .....++.++..+.+.++.++..++..+..++..... ....+...++++.+...+...+ +.++..++.+|..++....
T Consensus        84 ~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~  163 (530)
T 1WA5_B           84 QLQQELPQMTQQLNSDDMQEQLSATVKFRQILSREHRPPIDVVIQAGVVPRLVEFMRENQPEMLQLEAAWALTNIASGTS  163 (530)
T ss_dssp             ---CCHHHHHHHHSCSSHHHHHHHHHHHHHHTCCSSSCSHHHHHHTTCHHHHHHTTSTTSCHHHHHHHHHHHHHHTTSCH
T ss_pred             HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCCCCCHHHHHHcChHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCH
Confidence            3445566666777777777888888888887653221 1223333457777777776543 6677888899988876443


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      .....+...++++.+...+. ..++.++..++.++..++... .....+.. ++++.|+.++...               
T Consensus       164 ~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------  227 (530)
T 1WA5_B          164 AQTKVVVDADAVPLFIQLLY-TGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSN---------------  227 (530)
T ss_dssp             HHHHHHHHTTCHHHHHHHHH-HCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSC---------------
T ss_pred             HHHHHHhcCChHHHHHHHHh-CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhhCC---------------
Confidence            33333333466777777776 556788899999999988753 23333333 6777777776521               


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                       ++++...+..+|..-...                     ...........+++..|...+..      .+......+..
T Consensus       228 -~~~v~~~a~~~l~~l~~~---------------------~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~  279 (530)
T 1WA5_B          228 -KPSLIRTATWTLSNLCRG---------------------KKPQPDWSVVSQALPTLAKLIYS------MDTETLVDACW  279 (530)
T ss_dssp             -CHHHHHHHHHHHHHHHCC---------------------SSSCCCHHHHGGGHHHHHHHTTC------CCHHHHHHHHH
T ss_pred             -CHHHHHHHHHHHHHHHCC---------------------CCCCCCHHHHhhHHHHHHHHHhc------CCHHHHHHHHH
Confidence             344444444443221100                     00000011122334444333221      11111222222


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      .|.++...                                                  +......+.+.++++.|+.++.
T Consensus       280 ~l~~l~~~--------------------------------------------------~~~~~~~~~~~~~~~~l~~~l~  309 (530)
T 1WA5_B          280 AISYLSDG--------------------------------------------------PQEAIQAVIDVRIPKRLVELLS  309 (530)
T ss_dssp             HHHHHHSS--------------------------------------------------CHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHHHHcCC--------------------------------------------------CHHHHHHHHhCCHHHHHHHHhc
Confidence            22222110                                                  0001112345567778888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQ  635 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~g  635 (747)
                       ..++.++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++++|.+++... .. ..+...+
T Consensus       310 -~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~  383 (530)
T 1WA5_B          310 -HESTLVQTPALRAVGNIVTGNDL-----QTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAVIDAN  383 (530)
T ss_dssp             -CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTT
T ss_pred             -CCChhHHHHHHHHHHHHHhCCHH-----HHHHHHHCChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCC
Confidence             46777888999999998875332     1223344578888999988888889999999999998762 22 3334456


Q NP_000290.2     636 VFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP---QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       636 iI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~---e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      +++.|..++.+      .++.++..++.+|.+++....   .....+.+.++++.|..++.+. ++.++..++.+|.+++
T Consensus       384 ~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~  456 (530)
T 1WA5_B          384 LIPPLVKLLEV------AEYKTKKEACWAISNASSGGLQRPDIIRYLVSQGCIKPLCDLLEIA-DNRIIEVTLDALENIL  456 (530)
T ss_dssp             CHHHHHHHHHH------SCHHHHHHHHHHHHHHHHHTTTCTHHHHHHHHTTCHHHHHHHTTTC-CHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHHc------CCHHHHHHHHHHHHHHHcCCCCCHHHHHHHHHCCCHHHHHHHccCC-CHHHHHHHHHHHHHHH
Confidence            77888888876      367889999999999987532   2334444557788888888866 7788999999999998


Q NP_000290.2     713 SSKE  716 (747)
Q Consensus       713 ~~~~  716 (747)
                      ...+
T Consensus       457 ~~~~  460 (530)
T 1WA5_B          457 KMGE  460 (530)
T ss_dssp             HHHH
T ss_pred             HHHH
Confidence            7654


No 86
>1EE4_A KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=97.51  E-value=5.1e-08  Score=96.57  Aligned_cols=115  Identities=13%  Similarity=0.098  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        87 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  166 (423)
T 1EE4_A           87 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  166 (423)
T ss_dssp             THHHHHHHHHHHSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSCCHHHHHHHHHHHHHHHCCSTTCCCH
T ss_pred             ChHHHHHHHHhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCCCCCh
Confidence            34556666676777888889999999887654433333444467777888887777888888999998887644222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ....++++.+...+. ..++.++..++.++..+...
T Consensus       167 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  201 (423)
T 1EE4_A          167 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDG  201 (423)
T ss_dssp             HHHGGGHHHHHHHTT-CSCHHHHHHHHHHHHHHTSS
T ss_pred             HHHhhHHHHHHHHHH-cCCHHHHHHHHHHHHHHhcC
Confidence            233455666666665 45567777778887777654


No 87
>1EE4_B KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=97.51  E-value=5.1e-08  Score=96.57  Aligned_cols=115  Identities=13%  Similarity=0.098  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        87 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  166 (423)
T 1EE4_B           87 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  166 (423)
T ss_dssp             THHHHHHHHHHHSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHGGGSCCHHHHHHHHHHHHHHHCCSSSCCCH
T ss_pred             ChHHHHHHHHhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCCCCCh
Confidence            34556666676777888889999999887654433333444467777888887777888888999998887644222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ....++++.+...+. ..++.++..++.++..+...
T Consensus       167 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  201 (423)
T 1EE4_B          167 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDG  201 (423)
T ss_dssp             HHHGGGHHHHHHHTT-CSCHHHHHHHHHHHHHHHSS
T ss_pred             HHHhhHHHHHHHHHH-cCCHHHHHHHHHHHHHHhcC
Confidence            233455666666665 45567777778887777654


No 88
>4I2Z_A Protein UNC-45, Heat shock protein; chaperone, myosin folding, protein filaments; 2.9A {Caenorhabditis elegans}
Probab=97.51  E-value=6.2e-08  Score=114.34  Aligned_cols=431  Identities=14%  Similarity=0.098  Sum_probs=219.4  Template_Neff=8.600

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE--T  325 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~--l  325 (747)
                      +.++.++.+.+..++..++.+|.......... ..+. ...++.|..++.+.++.++..++..|..+..........  .
T Consensus       443 ~~l~~~~~~~~~~~~~~a~~~l~~~~~~~~~~-~~i~-~~~v~~L~~l~~~~~~~v~~~A~~~L~kL~~~~~~~~~~~~~  520 (961)
T 4I2Z_A          443 PIMLEMAASQDHLMQGIAAELIVATVSKHERA-INML-KVGIPVLRALYDSEDPTVKVRALVGLCKIGAAGGDDISKATM  520 (961)
T ss_dssp             HHHHHHHHSSCHHHHHHHHHHHHTTCCSSSSS-CHHH-HTHHHHHHHHHHCSSHHHHHHHHTTSSCC-------------
T ss_pred             HHHHHHhcCCCHHHHHHHHHHHHHHcChhHHH-HHHH-HhHHHHHHHHHhCCCHHHHHHHHHHHHHHHhcCCcchhhhcc
Confidence            33334455556667777777777554332111 1122 235677777777778889999999999887643321110  1


Q NP_000290.2     326 ---RRQNGIREAVSLLRRT--GNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVV  398 (747)
Q Consensus       326 ---l~~~IL~~Ll~lL~ss--~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~~  398 (747)
                         ....+...+..++...  .+..++..++..|..+.........+..  ++++.|++++...-+...-|       ++
T Consensus       521 ~~~~~~~L~~~~~~~l~~~~~~~~~~~~~A~e~Layls~~~~vke~l~~d~~~l~~L~~ll~~~~~~~~~~-------~~  593 (961)
T 4I2Z_A          521 KEEAVISLAKTCKKFLLETEKYSVDIRRYACEGLSYLSLDADVKEWIVDDSLLLKALVLLAKKAGALCVYT-------LA  593 (961)
T ss_dssp             ----CCHHHHHHHHHHHCTTTSCHHHHHHHHHHHHHHTTSHHHHHHHHHCHHHHHHHHHHHHHHGGGGSHH-------HH
T ss_pred             chHHHHHHHHHHHHHHhcCcCCChHHHHHHHHHHHHHhcCHHHHHHHhcCHHHHHHHHHHHHHcChhHHHH-------HH
Confidence               0112344444555411  2456888999999999876655555554  68888888887542111111       00


Q NP_000290.2     399 DPEVFFNATGCL-RKRLG--MRELLALVPQRATSSRVNLSSADAGRQTMR--NYSGLIDSLMAYVQNCVAASRCDDKSVE  473 (747)
Q Consensus       399 ~~~~~~~~~~~~-~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~  473 (747)
                        ..+-|-+... ++.+.  |.+|..+..+.... ...+...+.-....+  --.|.+..|.+.+..      -+....+
T Consensus       594 --~~l~nl~~~~~~~~~~~e~~~l~~~a~~~~~~-~~~~d~~~~v~~r~~~l~~~g~~~~Lv~ll~~------~s~~~r~  664 (961)
T 4I2Z_A          594 --TIYANLSNAFEKPKVDEEMVKLAQFAKHHVPE-THPKDTEEYVEKRVRALVEEGAVPACVAVSKT------ESKNALE  664 (961)
T ss_dssp             --HHHHHHTTCCCCCC----------CCCCSSTT-CCTTSSTTHHHHHHHHHHHSCSHHHHHHTCCC------SCSHHHH
T ss_pred             --HHHHHHhcCCCCCCCCHHHHHHHHHHhcCCCC-CCcCCCHHHHHHHHHHHHHCCCHHHHHHHhcC------CCHHHHH
Confidence              0111111100 00000  11222221111110 000111111111111  113445555444432      1233445


Q NP_000290.2     474 NCMCVLHNLSYRLDAEVPTRYRQLEYNARNAY-------TE---KSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWL  543 (747)
Q Consensus       474 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-------~~---~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~l  543 (747)
                      .+..++++++-.-  +  .|-.-.+..+-..-       ++   .....+..+-..     .-+..+.+...        
T Consensus       665 ~~~~~l~~l~~~~--~--~R~~iv~~G~v~~Ll~ll~~~~~~~~~~Aa~ALa~l~~-----~~~p~~~~~~~--------  727 (961)
T 4I2Z_A          665 LIARSLLAFAEYE--D--LRGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA-----KADPMISFPGQ--------  727 (961)
T ss_dssp             HHHHHHHTTSCSS--T--THHHHTTTTHHHHHHHHHHHSCTHHHHHHHHHHHHHSS-----SSCSTTTSTTT--------
T ss_pred             HHHHHHHHHhCCH--H--HHHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc-----cCChhhhcCCc--------
Confidence            5666777776211  1  11110111100000       00   000000000000     00000111111        


Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNM  622 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnL  622 (747)
                      ...++++.|+.+|..+.+...+..++.+|.+|+..++.     ....+.+.++++.|..+|. +.++.++..|+.++.+|
T Consensus       728 ~~~~~i~pLv~lL~~~~~~~~~~eal~ALtnLa~~~~~-----~~~~I~~~~~~~~l~~lL~~~~~~~vr~aA~ell~nL  802 (961)
T 4I2Z_A          728 RAYEVVKPLCDLLHPDVEGKANYDSLLTLTNLASVSDS-----IRGRILKEKAIPKIEEFWFMTDHEHLRAAAAELLLNL  802 (961)
T ss_dssp             HHHHTTSHHHHTTSCCSSCTTHHHHHHHHHHHHSSCHH-----HHHHHHHTTCHHHHGGGTSCSSCHHHHHHHHHHHHHS
T ss_pred             chhhHHHHHHHHhCCCCChHHHHHHHHHHHHHHcCCHH-----HHHHHHhcChHHHHHHHHhcCCCHHHHHHHHHHHHHH
Confidence            01267899999987334556778899999999986533     3445566788999999888 77889999999999999


Q NP_000290.2     623 SRHPLL-HRVM--GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS--SMLNNIINLCRSSAS  697 (747)
Q Consensus       623 a~~~e~-~~ll--~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~--giL~~Ll~LL~s~~d  697 (747)
                      +.++.. ..+.  ..+.+..++.++.+.     .+..++..|+.+|..++. .+.....+++.  +.+..+..++.+. +
T Consensus       803 ~~~~~~~~~~~~~~~~~~~ll~~l~~~~-----~d~~~~~aA~~aLa~ls~-~~~~~~~i~~~~~~~~~il~~ll~~~-~  875 (961)
T 4I2Z_A          803 LFFEKFYEETVAPGTDRLKLWVLYSAEV-----EEERLSRASAAGFAILTE-DENACARIMDEIKSWPEVFKDIAMHE-D  875 (961)
T ss_dssp             SSSTTSSTTTTSSCCTHHHHHHHHHHSC-----SSSTHHHHHHHHHHHHHT-CHHHHHHHTTTCTTHHHHHHHHHHCS-S
T ss_pred             HcCHHHHHhhCCCCCccchhhhHHhccC-----CCHHHHHHHHHHHHHHhC-CHHHHHHHHHHHhchHHHHHHHhhCC-C
Confidence            976544 2221  223444454443331     367888999999999884 46655555553  3466677777666 7


Q NP_000290.2     698 PKAAEAARLLLSDMWS-SKELQGVLRQQG  725 (747)
Q Consensus       698 ~eVr~aAL~aLsnL~~-~~~~~~~~~~~~  725 (747)
                      +.++..++.+|.+++. +.++...+-+.|
T Consensus       876 ~~l~~ra~~~L~nl~~~~~~~~~~i~~~g  904 (961)
T 4I2Z_A          876 AETQRRGLMGIANIMHSSNKLCSEIVSSE  904 (961)
T ss_dssp             TTHHHHHHHHHTTTSSSCHHHHTCCTTHH
T ss_pred             HHHHHHHHHHHHHHHhcCHHHHHHHHhcc
Confidence            8899999999999965 444444343344


No 89
>5XZX_A Importin subunit alpha-3, Ran-binding protein; nuclear import, TRANSPORT PROTEIN; 3.0A {Homo sapiens}
Probab=97.48  E-value=6.3e-08  Score=95.65  Aligned_cols=360  Identities=17%  Similarity=0.182  Sum_probs=211.7  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+. ..++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++...+.....
T Consensus        46 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  125 (416)
T 5XZX_A           46 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  125 (416)
T ss_dssp             CHHHHHHHTTCTTCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHH
T ss_pred             cHHHHHHHhcCCCCHHHHHHHHHHHHHHhcCChHHHHHHHhcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            4555666665 456678888888888887654433333334567777888887777888999999999887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....++.++..++.++..++..........  .++++.+..++..                .++++
T Consensus       126 ~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~~  189 (416)
T 5XZX_A          126 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHH----------------TDVNI  189 (416)
T ss_dssp             HHHHTCHHHHTTSCSTTSCHHHHHHHHHHHHHHHHCCSSCCCHHHHHHHHHHHHHHTTC----------------CCHHH
T ss_pred             HHHCccHHHHHHhcCCCCCHHHHHHHHHHHHHHhcCCCCCCChhHHHHHHHHHHHHHhC----------------CCHHH
Confidence            33345667777776533456778888888888876533211111  1566666666542                13444


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..++..-...      .+              .....+ --.+++..+...++.      -+..-...+...|.++
T Consensus       190 ~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l  242 (416)
T 5XZX_A          190 LVDTVWALSYLTDA------GN--------------EQIQMV-IDSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  242 (416)
T ss_dssp             HHHHHHHHHHHHHH------CH--------------HHHHHH-HHHTCHHHHGGGGGC------SCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhhc------CH--------------HHHHHH-HHCChHHHHHHHcCC------CCHHHHHHHHHHHHHH
Confidence            44444333221100      00              000000 001334444333321      0111111222222222


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.+..++. +.++
T Consensus       243 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  271 (416)
T 5XZX_A          243 VTGT--------------------------------------------------DEQTQVVLNCDALSHFPALLT-HPKE  271 (416)
T ss_dssp             TTSC--------------------------------------------------HHHHHHHHTTTCGGGSHHHHT-CSCH
T ss_pred             HcCC--------------------------------------------------HHHHHHHcCcccHHHHHHHhc-CCCH
Confidence            1100                                                  001111234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.. . .. ..+...++++.
T Consensus       272 ~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~  346 (416)
T 5XZX_A          272 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  346 (416)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHH
T ss_pred             HHHHHHHHHHHHHhcCCHH-----HHHHHHhCCHHHHHHHHHHcCCHHHHHHHHHHHHHHHHhcCHHHHHHHHHCCCHHH
Confidence            8888999999998765332     223334556888888888888888999999999999864 2 11 22334567788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDM  711 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL  711 (747)
                      +..++.+      .++.++..++.+|.+++...+...    ..+.+.++++.+..++.+. ++.++..++.+|.++
T Consensus       347 l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~~  415 (416)
T 5XZX_A          347 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQF  415 (416)
T ss_dssp             HHTTTTS------SCHHHHHHHHHHHHHHHHHCSTTHHHHHHHHHHTTHHHHHHTTCCTT-CHHHHHHHHHHHHHH
T ss_pred             HHHHccC------CCHHHHHHHHHHHHHHHHHhHHhHHHHHHHHHHcCHHHHHHHHhhCC-cHHHHHHHHHHHHHh
Confidence            8888776      367888899999999987533211    1233345677888888766 778888888887764


No 90
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=97.46  E-value=6.9e-08  Score=85.28  Aligned_cols=134  Identities=25%  Similarity=0.287  Sum_probs=89.4  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++..+..++...+.....+...++++.+...+.+.++.++..++.++..++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (202)
T 5MFO_F            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV   84 (202)
T ss_dssp             THHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            34556666666777888889999988876544444444445677888888887778888999999999886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  140 (202)
T 5MFO_F           85 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  140 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhc
Confidence            34456777777776 4566778888888888876422 2222223 55666666554


No 91
>3SL9_E Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: PEG, GOL, IMD, EDO; 2.2A {Homo sapiens}
Probab=97.46  E-value=7.2e-08  Score=83.64  Aligned_cols=134  Identities=16%  Similarity=0.201  Sum_probs=88.4  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLG-GICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~-IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.++.++..... ....+.... +++.+..++.. .+..++..++.++..++.. ....
T Consensus        13 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~   90 (167)
T 3SL9_E           13 RAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEA-SRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGL   90 (167)
T ss_dssp             HHHHHHHHHHTCSCHHHHHHHHHHHHHHTTSHH-HHHHHHTCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTS-HHHH
T ss_pred             CcHHHHHHHhCCCCHHHHHHHHHHHHHHccCHH-HHHHHHhCCchHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHH
Confidence            345556666666667788889999998876543 222233323 77777777776 6677888889999888743 3333


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      ..+...+.++.+..++. ..++.++..++.++.+++.........+.  ++++.|++++..
T Consensus        91 ~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  150 (167)
T 3SL9_E           91 LAIFKSGGIPALVKMLG-SPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNK  150 (167)
T ss_dssp             HHHHHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHCTTHHHHHHHTTHHHHHHHHHHH
T ss_pred             HHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHcCCHhHHHHHHHcCHHHHHHHHhcC
Confidence            33444567777888776 55677888899999998875433333332  667777777654


No 92
>3NOW_A SD10334p; Armadillo Repeat, Hsp90, Myosin, Tetra-tricopeptide; 2.992A {Drosophila melanogaster}
Probab=97.46  E-value=7.3e-08  Score=105.35  Aligned_cols=110  Identities=10%  Similarity=0.050  Sum_probs=66.2  Template_Neff=12.800

Q NP_000290.2     247 IPKAVQYLSSQ--DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       247 L~~Ll~lL~ss--d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +..++..+.+.  +..++..++..|..++... .........+.++.+...+.. .+..++..++.++..++........
T Consensus         8 i~~l~~~l~~~~~~~~~r~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~~~~   86 (810)
T 3NOW_A            8 VKQMMDLTFDLATPIDKRRAAANNLVVLAKEQ-TGAELLYKDHCIAKVASLTKVEKDQDIYVNMVHLVAALCENSVERTK   86 (810)
T ss_dssp             HHHHHHHHHSSCCSSHHHHHHHHHHHHHSSCH-HHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             HHHHHHHHhcCCCcHHHHHHHHHHHHHHhccc-cccHHHHccccHHHHHHHhcCCCCHHHHHHHHHHHHHHHHcCHhHHH
Confidence            33445555554  5778888888888887654 222223334567777777731 5678888999999888765332222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .......++.+...+. ..++.++..++.++..++
T Consensus        87 ~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~~~  120 (810)
T 3NOW_A           87 GVLTELGVPWFMRVLD-QKHENCVSTAQFCLQTIL  120 (810)
T ss_dssp             HHHHHSCHHHHHHHHH-CCSTTHHHHHHHHHHHHH
T ss_pred             HHHHHhcHHHHHHHhc-CCChhHHHHHHHHHHHHH
Confidence            2222334566666665 345556666666666554


No 93
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=97.44  E-value=7.9e-08  Score=84.90  Aligned_cols=134  Identities=25%  Similarity=0.287  Sum_probs=89.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++..+..++...+.....+...++++.+...+.+.++.++..++.++..++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (202)
T 5MFO_E            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV   84 (202)
T ss_dssp             CHHHHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            34556666666777888889999988876544434444445677888888887788889999999999886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  140 (202)
T 5MFO_E           85 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  140 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhc
Confidence            34456777777775 4566778888888888876422 2222223 55666666554


No 94
>4XZR_B Heh1-NLS, Kap60; karyopherins  nuclear import ; 2.25A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.44  E-value=8.1e-08  Score=95.04  Aligned_cols=115  Identities=13%  Similarity=0.098  Sum_probs=77.3  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++.........
T Consensus        87 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~  166 (423)
T 4XZR_B           87 DAVPLFIQLLYTGSVEVKEQAIWALGNVAGDSTDYRDYVLQCNAMEPILGLFNSNKPSLIRTATWTLSNLCRGKKPQPDW  166 (423)
T ss_dssp             TCHHHHHHHHHHSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCHHHHHHHTTSCCHHHHHHHHHHHHHHHCCCTTCCCH
T ss_pred             chHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCCCCCCh
Confidence            34556666677777888899999999887654433333444467777888887777888888999998887654222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ....++++.+...+. ..++.++..++.++..++..
T Consensus       167 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  201 (423)
T 4XZR_B          167 SVVSQALPTLAKLIY-SMDTETLVDACWAISYLSDG  201 (423)
T ss_dssp             HHHGGGHHHHHHHTT-CSCHHHHHHHHHHHHHHTSS
T ss_pred             HHhccHHHHHHHHhh-CCCHHHHHHHHHHHHHHhcC
Confidence            233346666666665 44566777777777777654


No 95
>3OPB_A SWI5-dependent HO expression protein 4; HEAT and ARM fold, Myosin; 2.9A {Saccharomyces cerevisiae}
Probab=97.44  E-value=9.1e-08  Score=108.58  Aligned_cols=168  Identities=20%  Similarity=0.242  Sum_probs=116.3  Template_Neff=10.500

Q NP_000290.2     546 SDAIRTYLNLMGKSK-------------KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVV  612 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~-------------d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr  612 (747)
                      .++++.|+.++....             +..++..++.+|.+++.......+......+...++++.|..++.+.++.++
T Consensus       544 ~~~l~~L~~lL~~~~~~~~~~~~~~~~~~~~~~~~al~aL~~l~~~~~~~~~~~~~~~~~~~~~~~~L~~ll~~~~~~v~  623 (778)
T 3OPB_A          544 LNAIPFLFELLPRSTPVDDNPLHNDEQIKLTDNYEALLALTNLASSETSDGEEVCKHIVSTKVYWSTIENLMLDENVPLQ  623 (778)
T ss_dssp             TTHHHHHHHTSCCSSSCSSCC---CCCCCHHHHHHHHHHHHHHHHCCSHHHHHHHHHHHHSHHHHHHHHHGGGCSSHHHH
T ss_pred             cchHHHHHHHCCCCCCCCCCCCCChhhccHHHHHHHHHHHHHHhcCCCCCCHHHHHHHHhcccHHHHHHHHhhCCCHHHH
Confidence            456677777765211             4567778999999988752200000011222224688888888888888899


Q NP_000290.2     613 RSGASLLSNMSRHPLL--HRVMGN------QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS-SS  683 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~--~~ll~~------giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve-~g  683 (747)
                      ..++.+|++++.....  ..++..      ++++.|+.++..      .+..++..++++|++++...+.....++. .+
T Consensus       624 ~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~~~l~~L~~ll~~------~~~~v~~~a~~~L~~l~~~~~~~~~~l~~~~~  697 (778)
T 3OPB_A          624 RSTLELISNMMSHPLTIAAKFFNLENPQSLRNFNILVKLLQL------SDVESQRAVAAIFANIATTIPLIAKELLTKKE  697 (778)
T ss_dssp             HHHHHHHHHHHTSGGGTGGGTSCCSSHHHHHHHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHCHHHHHHHTTCHH
T ss_pred             HHHHHHHHHHhcChhHHHHHhcCCCChhHHHhHHHHHHHhcC------CCHHHHHHHHHHHHHHHccCHHHHHHHhcCcc
Confidence            9999999999987432  233332      678888888876      36789999999999997655554444443 67


Q NP_000290.2     684 MLNNIINLCRSS-ASPKAAEAARLLLSDMWSSKELQG  719 (747)
Q Consensus       684 iL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~~~~~~  719 (747)
                      +++.|+.++.+. .+..++..++++|.+++...+...
T Consensus       698 ~i~~L~~~L~~~~~~~~l~~~a~~aL~~L~~~~~~~~  734 (778)
T 3OPB_A          698 LIENAIQVFADQIDDIELRQRLLMLFFGLFEVIPDNG  734 (778)
T ss_dssp             HHHHHHHHHHHTTTCHHHHHHHHHHHHHHHTTCCSTT
T ss_pred             HHHHHHHHHHhCCCCHHHHHHHHHHHHHHHhhCCcCC
Confidence            889999998862 167789999999999997766544


No 96
>4I2W_A Protein UNC-45, Heat shock 70; chaperone, myosin folding, protein filaments; 3.6A {Caenorhabditis elegans}
Probab=97.43  E-value=1e-07  Score=112.49  Aligned_cols=433  Identities=14%  Similarity=0.102  Sum_probs=221.5  Template_Neff=8.600

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE--  324 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~--  324 (747)
                      ++.++.++.+.+..++..++.+|..+....... ..+. ...++.|..++.+.++.++..++..|..+..........  
T Consensus       442 ~~~l~~l~~~~~~~~~~~a~~~l~~~~~~~~~~-~~i~-~~~v~~L~~l~~~~~~~v~~~A~~~L~kL~~~~~~~~~~~~  519 (961)
T 4I2W_A          442 TPIMLEMAASQDHLMQGIAAELIVATVSKHERA-INML-KVGIPVLRALYDSEDPTVKVRALVGLCKIGAAGGDDISKAT  519 (961)
T ss_dssp             HHHHHHHHHSSCHHHHHTTTTTTTTTCCSCSSS-HHHH-HHHHHHHHHHHHCSCHHHHHHHHTTSSSCCC----------
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHcChhHHH-HHHH-HhHHHHHHHHHhCCCHHHHHHHHHHHHHHHhcCCcchhhhc
Confidence            333334455556667777777777554332111 1122 235677777777778889999999999887543321100  


Q NP_000290.2     325 T---RRQNGIREAVSLLRRT--GNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       325 l---l~~~IL~~Ll~lL~ss--~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                      .   ....+...+..++...  .+..++..++..|..+.........+..  .+++.|++++...-+...-|-       
T Consensus       520 ~~~~~~~~l~~~~~~~l~~~~~~~~~~~~~AvegLayLs~~~~vke~l~~d~~~l~~L~~ll~~~~~~~~~~~-------  592 (961)
T 4I2W_A          520 MKEEAVISLAKTCKKFLLETEKYSVDIRRYACEGLSYLSLDADVKEWIVDDSLLLKALVLLAKKAGALCVYTL-------  592 (961)
T ss_dssp             --CCCTTHHHHHHHHHHHCCSSSCHHHHHHHHHHHHHTCSSHHHHHHHHHCHHHHHHHHHHHHHHGGGSHHHH-------
T ss_pred             cchHHHHHHHHHHHHHHhcCcCCChHHHHHHHHHHHHHhcCHHHHHHHhcCHHHHHHHHHHHHHcChhHHHHH-------
Confidence            1   0112344455555411  2456888999999999876655555554  688889888875422111111       


Q NP_000290.2     398 VDPEVFFNATGCL-RKRL--GMRELLALVPQRATSSRVNLSSADAGRQTMRN--YSGLIDSLMAYVQNCVAASRCDDKSV  472 (747)
Q Consensus       398 ~~~~~~~~~~~~~-~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~  472 (747)
                      +  ..+-|-+... ++.+  .|.+|..+..+..... ..+...+.-....+.  -.|.+..|.+.+..      -+....
T Consensus       593 ~--~~l~nl~~~~~~~~~~~e~~~l~~~a~~~~~~~-~~~d~~~~v~~r~~~l~~~g~~~~Lv~ll~~------~s~~~r  663 (961)
T 4I2W_A          593 A--TIYANLSNAFEKPKVDEEMVKLAQFAKHHVPET-HPKDTEEYVEKRVRALVEEGAVPACVAVSKT------ESKNAL  663 (961)
T ss_dssp             H--HHHHHTTTCCCCCC----------CCCCCSTTC-TTTTSSTTHHHHHHHHHHSSSSHHHHHTTCC------CCSHHH
T ss_pred             H--HHHHHHhcCCCCCCCCHHHHHHHHHHhcCCCCC-CcCCCHHHHHHHHHHHHHCCCHHHHHHHhcC------CCHHHH
Confidence            0  0111111110 0000  0122222211111110 011111111111111  12444444444332      122334


Q NP_000290.2     473 ENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAY---T-E------KSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW  542 (747)
Q Consensus       473 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~---~-~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~  542 (747)
                      +.+..+|++++-.-  +.  |-.-.+..+-..-   . +      .....+..+-..     .-+..+.+...       
T Consensus       664 ~~~~~~l~~l~~~~--~~--R~~ivq~g~~~~Ll~ll~~~~~~~~~~Aa~ALa~l~~-----~~~p~~~~~~~-------  727 (961)
T 4I2W_A          664 ELIARSLLAFAEYE--DL--RGRIIAEGGTVLCLRLTKEASGEGKIKAGHAIAKLGA-----KADPMISFPGQ-------  727 (961)
T ss_dssp             HHHHHHHHTTSSSS--TT--TTTTTTSSHHHHHHHHHHHSTTHHHHHHHHHHHTTSS-----SSCGGGTSTTT-------
T ss_pred             HHHHHHHHHHhCCH--HH--HHHHHHCchHHHHHHHHhcCChHHHHHHHHHHHHHHc-----cCChhhhcCCc-------
Confidence            55566777776211  11  1000001100000   0 0      000000000000     00000111111       


Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSN  621 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsn  621 (747)
                       ...++++.|+.+|..+.+...+..++.+|.+|+..++.     ....+.+.++++.|..+|. +.++.++..|+.++.+
T Consensus       728 -~~~~~i~pLv~lL~~~~~~~~~~eal~ALtnLa~~~~~-----~~~~I~~~~~~~~l~~lL~~~~~~~vr~aA~ell~n  801 (961)
T 4I2W_A          728 -RAYEVVKPLCDLLHPDVEGKANYDSLLTLTNLASVSDS-----IRGRILKEKAIPKIEEFWFMTDHEHLRAAAAELLLN  801 (961)
T ss_dssp             -HHHHTTSGGGTSSSCCSSCTTTTTTHHHHHHHSSSCHH-----HHHHHHHTTCHHHHTTSSSCSTTHHHHHHHHHHHHT
T ss_pred             -chhhHHHHHHHHhCCCCChHHHHHHHHHHHHHHcCCHH-----HHHHHHhcChHHHHHHHHhcCCCHHHHHHHHHHHHH
Confidence             11267899999987334556778899999999986533     3445556788899998888 7788999999999999


Q NP_000290.2     622 MSRHPLL-HRVM--GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS--SMLNNIINLCRSSA  696 (747)
Q Consensus       622 La~~~e~-~~ll--~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~--giL~~Ll~LL~s~~  696 (747)
                      |+.++.. ..+.  ..+.+..++.++.+.     .++.++..|+.+|+.++. .+.....+++.  +.+..|..++.+. 
T Consensus       802 L~~~~~~~~~~~~~~~~~~~ll~~l~~~~-----~d~~~~~aA~~aLa~l~~-~~~~~~~i~~~~~~~~~~l~~ll~~~-  874 (961)
T 4I2W_A          802 LLFFEKFYEETVAPGTDRLKLWVLYSAEV-----EEERLSRASAAGFAILTE-DENACARIMDEIKSWPEVFKDIAMHE-  874 (961)
T ss_dssp             TSSSSSSSTTTSSSCSSCHHHHHHHHHCC-----SSSTHHHHHHHHHHHHHS-SHHHHHHTGGGCTTHHHHHHHHHHCS-
T ss_pred             HHcCHHHHHhhCCCCCccchhhhHHhccC-----CCHHHHHHHHHHHHHHhC-CHHHHHHHHHHHhchHHHHHHHhhCC-
Confidence            9976544 2221  223444444443331     357888999999999884 45555555553  3466677777666 


Q NP_000290.2     697 SPKAAEAARLLLSDMWS-SKELQGVLRQQGF  726 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~-~~~~~~~~~~~~~  726 (747)
                      ++.++..++.+|.+++. +.+....+.+.|.
T Consensus       875 ~~~l~~ra~~~l~nl~~~~~~~~~~~~~~g~  905 (961)
T 4I2W_A          875 DAETQRRGLMGIANIMHSSNKLCSEIVSSEV  905 (961)
T ss_dssp             STTHHHHHHHHTHHHHSSCSHHHHCCSSHHH
T ss_pred             CHHHHHHHHHHHHHHHhcCHHHHHHHHhccH
Confidence            78899999999999965 4444443444443


No 97
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=97.42  E-value=9.1e-08  Score=88.50  Aligned_cols=221  Identities=45%  Similarity=0.773  Sum_probs=134.5  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQD--EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd--~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ..++.++..+...+  ..++..++.++.+++.........+...++++.+..++...+..++..++.+|.+++.......
T Consensus         8 ~~i~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~   87 (233)
T 3TT9_A            8 MTLERAVSMLEADHMLPSRISAAATFIQHECFQKSEARKRVNQLRGILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNK   87 (233)
T ss_dssp             CCHHHHHHTCCSSCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHTTHHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHH
T ss_pred             hHHHHHHHHHhhcCCCHHHHHHHHHHHHHHHccCHHHHHHHHHcchHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCCcHH
Confidence            34556666666544  6788888899988876444444445555678888888877777888999999999886444444


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      ..+...+.++.++.++....+..++..++.++.+++........+.. +++..+..++.... .+-.....+.....+++
T Consensus        88 ~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~ll~~~~-~~~~~~~~~~~~~~~~~  166 (233)
T 3TT9_A           88 LEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSNDKLKNLMITEALLTLTENIIIPFS-GWPEGDYPKANGLLDFD  166 (233)
T ss_dssp             HHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTSGGGHHHHHHHHHHHHCCCCCHHHH-CCCGGGCCCCCTTCCHH
T ss_pred             HHHHHcccHHHHHHHHhhCCCHHHHHHHHHHHHHHccCHHHHHHhhhhcHHHHHHHHHhhcc-CCCCCCCCcccCCCcHH
Confidence            44445567777887775234567888999999999875544444444 66666666665432 11111222222334566


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSS-ADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLH  480 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  480 (747)
                      +...+.++|..                     +.. .+..++.+....++++.|...++....-...+.+-.+++..+|.
T Consensus       167 ~~~~a~~~l~~---------------------l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~L~  225 (233)
T 3TT9_A          167 IFYNVTGCLRN---------------------MSSAGADGRKAMRRCDGLIDSLVHYVRGTIADYQPDDKATENCVCILH  225 (233)
T ss_dssp             HHHHHHHHHHH---------------------HTTSCHHHHHHHHTSTTHHHHHHHHHHHHHHTTCTTCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHH---------------------HHhcCHHHHHHHHHcccHHHHHHHHHHcccccCCCChHHHHHHHHHHH
Confidence            65555555432                     111 22334444444455666666554421101115567788999999


Q NP_000290.2     481 NLSYRLD  487 (747)
Q Consensus       481 ~~~~~~~  487 (747)
                      ||+++.+
T Consensus       226 ~l~~~~~  232 (233)
T 3TT9_A          226 NLSYQLE  232 (233)
T ss_dssp             HHCCCCC
T ss_pred             Hhhhccc
Confidence            9987654


No 98
>2Z6H_A Catenin beta-1; Beta-Catenin, C-terminal Domain, Activator, Cell; 2.2A {Homo sapiens}
Probab=97.42  E-value=9.4e-08  Score=103.88  Aligned_cols=378  Identities=17%  Similarity=0.155  Sum_probs=229.8  Template_Neff=11.700

Q NP_000290.2     241 ECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       241 ~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~  319 (747)
                      +....+++.+...+.+.++.++..++.++..+..............+++..+...+. ..+..++..++.+|..++....
T Consensus        10 ~~~~~~i~~L~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~~~~~~~~~i~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~   89 (644)
T 2Z6H_A           10 ELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHRE   89 (644)
T ss_pred             HHhCCHHHHHHHHcCCCCHHHHHHHHHHHHHHhCCcHHHHHHHhCCChHHHHHHHHcCCCCHHHHHHHHHHHHHHhCCHH
Confidence            344566777888888778889999999999887653222111111346666777666 4566788888888888865432


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK-EELIA-DALPVLADRVIIPFSGWCDGNSNMSREV  397 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~-~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~  397 (747)
                       ....+...+.++.+...+. ..++.++..++.++..++...... ..+.. ++++.|+.++...               
T Consensus        90 -~~~~~~~~~~i~~L~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~---------------  152 (644)
T 2Z6H_A           90 -GLLAIFKSGGIPALVKMLG-SPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKT---------------  152 (644)
T ss_pred             -HHHHHHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCC---------------
Confidence             2223333467777888876 556788889999999988653322 22222 6677777766531               


Q NP_000290.2     398 VDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMC  477 (747)
Q Consensus       398 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  477 (747)
                       ++++...+..+|..-....                    ...+..... .++++.|...+...     .+.+....++.
T Consensus       153 -~~~~~~~a~~~L~~l~~~~--------------------~~~~~~~~~-~~~~~~L~~~l~~~-----~~~~~~~~a~~  205 (644)
T 2Z6H_A          153 -NVKFLAITTDCLQILAYGN--------------------QESKLIILA-SGGPQALVNIMRTY-----TYEKLLWTTSR  205 (644)
T ss_pred             -CHHHHHHHHHHHHHHhcCC--------------------HHHHHHHHH-CCcHHHHHHHhcCC-----CCHHHHHHHHH
Confidence             3344444444443211000                    000111111 23444444444321     12222233333


Q NP_000290.2     478 VLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMG  557 (747)
Q Consensus       478 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~  557 (747)
                      +|.+++..-                                                   .....+.+.++++.|+.++.
T Consensus       206 ~L~~l~~~~---------------------------------------------------~~~~~~~~~~~l~~l~~~l~  234 (644)
T 2Z6H_A          206 VLKVLSVCS---------------------------------------------------SNKPAIVEAGGMQALGLHLT  234 (644)
T ss_pred             HHHHHccCh---------------------------------------------------HHHHHHHHCCHHHHHHHHhc
Confidence            333332110                                                   00012345667888888887


Q NP_000290.2     558 KSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQ  635 (747)
Q Consensus       558 ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~g  635 (747)
                       ..+..++..++++|.+++.....      ...  ..++++.|+.++.+.+..++..++.+|.+++.. ... ..+...+
T Consensus       235 -~~~~~~~~~a~~~L~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~  305 (644)
T 2Z6H_A          235 -DPSQRLVQNCLWTLRNLSDAATK------QEG--MEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVG  305 (644)
T ss_pred             -CCCHHHHHHHHHHHHHHhcCCCC------HHH--HCchHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCC
Confidence             46778888999999999875321      111  256788888888888888999999999999865 222 2334556


Q NP_000290.2     636 VFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL---AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       636 iI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~---~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      +++.++..+...    ..+..++..++.+|.+++...+..   ...+...++++.|+.++....+..++..++.+|.+++
T Consensus       306 ~l~~L~~~l~~~----~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~v~~~a~~~L~~l~  381 (644)
T 2Z6H_A          306 GIEALVRTVLRA----GDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLA  381 (644)
T ss_pred             HHHHHHHHHhcC----CCCHHHHHHHHHHHHHHHcCCCCHHHHHHHHHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHh
Confidence            777777776521    035678889999999998753322   2333344677888888875435678899999999999


Q NP_000290.2     713 SSKELQGVLRQQGF  726 (747)
Q Consensus       713 ~~~~~~~~~~~~~~  726 (747)
                      ...+.+..+.+.|.
T Consensus       382 ~~~~~~~~l~~~~~  395 (644)
T 2Z6H_A          382 LCPANHAPLREQGA  395 (644)
T ss_pred             cCHHHHHHHHHCCc
Confidence            87776655555443


No 99
>4U2X_E eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=97.42  E-value=9.4e-08  Score=83.77  Aligned_cols=116  Identities=17%  Similarity=0.149  Sum_probs=80.4  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~  324 (747)
                      +++.+..++.+.++.++..++.++.++....+.....+...++++.+...+.+.+..++..++.++.+++.. .......
T Consensus         9 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   88 (175)
T 4U2X_E            9 ALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRY   88 (175)
T ss_dssp             SSHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHH
T ss_pred             hHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCChHHHHHHHHHhcCHHHHHHHHHHHHHHcCCCCHHHHHH
Confidence            455566666667788889999999998865443333444456777888887777778888899999988753 2222223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...+.++.+...+. ..++.++..++.++.+++....
T Consensus        89 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~  125 (175)
T 4U2X_E           89 LVALGCIKPLCDLLT-VMDSKIVQVALNGLENILRLGE  125 (175)
T ss_dssp             HHHHTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhcH
Confidence            333456777777776 5567788888899888887543


No 100
>4RV1_D Engineered Protein OR497; STRUCTURAL GENOMICS, PSI-BIOLOGY, PROTEIN STRUCTURE; 2.573A {SYNTHETIC CONSTRUCT}
Probab=97.42  E-value=9.1e-08  Score=94.28  Aligned_cols=363  Identities=20%  Similarity=0.249  Sum_probs=217.4  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.++.++..++.++..+...........
T Consensus        45 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  124 (420)
T 4RV1_D           45 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAI  124 (420)
T ss_dssp             HHHHHHHTTSCSCSSSHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHhCCChHHHHHH
Confidence            45556666666777888899999988876543333333334567777777777778888899999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      ...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++...                ++++-
T Consensus       125 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~~~  187 (420)
T 4RV1_D          125 VDAGGVEVLVKLLT-STDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTST----------------DSEVQ  187 (420)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCS----------------SHHHH
T ss_pred             HHcCHHHHHHHHHh-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCC----------------CHHHH
Confidence            33456777777776 55677888899999988864322 222222 5566666655421                23332


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..         +..            ........-.-.++++.+...+++      -+..-...+...|.++.
T Consensus       188 ~~~~~~l~~---------l~~------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~  240 (420)
T 4RV1_D          188 KEAARALAN---------IAS------------GPTSAIKAIVDAGGVEVLVKLLTS------TDSEVQKEAARALANIA  240 (420)
T ss_dssp             HHHHHHHHH---------HHT------------SCHHHHHHHHTTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHH---------HhC------------CCHHHHHHHHHCCHHHHHHHHhhC------CCHHHHHHHHHHHHHHh
Confidence            222222221         100            000000000001233333322221      01111122222222221


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...                                                  ......+.+.++++.++..+. +.++.
T Consensus       241 ~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~~  269 (420)
T 4RV1_D          241 SGP--------------------------------------------------DEAIKAIVDAGGVEVLVKLLT-STDSE  269 (420)
T ss_dssp             TSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSSHH
T ss_pred             CCC--------------------------------------------------HHHHHHHhhccHHHHHHHHhC-CCCHH
Confidence            100                                                  001111234567777888887 46677


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFPEVT  641 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~~Ll  641 (747)
                      ++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++... .. ......++++.+.
T Consensus       270 ~~~~~~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~  344 (420)
T 4RV1_D          270 VQKEAARALANIASGPDE-----AIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLV  344 (420)
T ss_dssp             HHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHH
T ss_pred             HHHHHHHHHHHHHcCCHH-----HHHHHHHCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcChHHHHHHHHHCCHHHHHH
Confidence            888899999998875332     1223344578888888888888889999999999998763 22 2333446777788


Q NP_000290.2     642 RLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       642 ~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. ++.++..++.+|..+....
T Consensus       345 ~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~  411 (420)
T 4RV1_D          345 KLLTS------TDSEVQKEAARALANIASGPTSAIKAIVDAGGVEVLQKLLTST-DSEVQKEAQRALENIKSGG  411 (420)
T ss_dssp             HHTTC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHHHHHHHHHHHHHTS
T ss_pred             HHhCC------CCHHHHHHHHHHHHHHHcCChhHHHHHHhccHHHHHHHHcCCC-CHHHHHHHHHHHHhhccCC
Confidence            77776      3678899999999999876444444455556788888888766 7789999999999887644


No 101
>4BQK_A IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER; TRANSPORT PROTEIN, HYDROLASE, NUCLEAR LOCALIZATION; HET: PEG; 1.997A {ORYZA SATIVA}
Probab=97.41  E-value=9.4e-08  Score=96.14  Aligned_cols=158  Identities=18%  Similarity=0.251  Sum_probs=116.4  Template_Neff=13.000

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.|+.++. +.++.++..++.+|.+++...+.     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       170 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  243 (456)
T 4BQK_A          170 TRPALPALARLIH-SNDEEVLTDACWALSYLSDGTND-----KIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVT  243 (456)
T ss_dssp             HTTHHHHHHHHTT-CCCHHHHHHHHHHHHHHTSSSHH-----HHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCChH-----HHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHc
Confidence            4456777888887 46778888899999998865332     22333456788889999888888899999999999987


Q NP_000290.2     625 HPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      ... . ..+...++++.+..++...     .++.++..++.+|.+++...+.....+...++++.|..++.+. ++.++.
T Consensus       244 ~~~~~~~~~~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~  317 (456)
T 4BQK_A          244 GDDAQTQCIIDHQALPCLLSLLTQN-----LKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLLQTA-EFDIKK  317 (456)
T ss_dssp             SCHHHHHHHHTTTHHHHHHHHHHSC-----CCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHHHHHS-CHHHHH
T ss_pred             CCHHHHHHHHHCChHHHHHHHHHcC-----CCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhhcC-CHHHHH
Confidence            632 2 2334446777888877652     2577889999999999876555555555666788888888766 778888


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       318 ~a~~~l~~l~~~  329 (456)
T 4BQK_A          318 EAAWAISNATSG  329 (456)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHcC
Confidence            999999988863


No 102
>5TBK_C Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=97.41  E-value=1e-07  Score=99.66  Aligned_cols=160  Identities=15%  Similarity=0.207  Sum_probs=115.0  Template_Neff=12.200

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .+.++++.|+.++....+..++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+|.+++
T Consensus       196 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~  270 (521)
T 5TBK_C          196 ISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDP-----PPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLT  270 (521)
T ss_dssp             HHTTCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSS-----CCCHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHH
T ss_pred             HHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCC-----CCCHHHHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHh
Confidence            45567788888886323446778899999998865321     1112223567888888888888889999999999998


Q NP_000290.2     624 RH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .. ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++
T Consensus       271 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  343 (521)
T 5TBK_C          271 DAGNEQIQMVIDSGIVPHLVPLLSH------QEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP-KEKIN  343 (521)
T ss_dssp             HHCHHHHHHHHHTTCHHHHGGGGGC------SSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCGGGHHHHHTCS-CHHHH
T ss_pred             ccChHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHhHHHHhhCC-CHHHH
Confidence            76 222 233445677788888765      3677888999999999876444444555557788888888766 78889


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       344 ~~a~~~l~~l~~~~  357 (521)
T 5TBK_C          344 KEAVWFLSNITAGN  357 (521)
T ss_dssp             HHHHHHHHHHTTSC
T ss_pred             HHHHHHHHHHhCCC
Confidence            99999999988653


No 103
>5TBK_D Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=97.41  E-value=1e-07  Score=99.66  Aligned_cols=160  Identities=15%  Similarity=0.207  Sum_probs=115.0  Template_Neff=12.200

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .+.++++.|+.++....+..++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+|.+++
T Consensus       196 ~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~  270 (521)
T 5TBK_D          196 ISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDP-----PPPMETIQEILPALCVLIHHTDVNILVDTVWALSYLT  270 (521)
T ss_dssp             HHTCCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSS-----CCCHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHH
T ss_pred             HHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCC-----CCCHHHHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHh
Confidence            45567788888886323446778899999998865321     1112223567888888888888889999999999998


Q NP_000290.2     624 RH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       624 ~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      .. ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++
T Consensus       271 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  343 (521)
T 5TBK_D          271 DAGNEQIQMVIDSGIVPHLVPLLSH------QEVKVQTAALRAVGNIVTGTDEQTQVVLNCDALSHFPALLTHP-KEKIN  343 (521)
T ss_dssp             HHCHHHHHHHHHTTCHHHHGGGGGC------SSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCGGGHHHHHHCS-CHHHH
T ss_pred             ccChHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHhHHHHhhCC-CHHHH
Confidence            76 222 233445677788888765      3677888999999999876444444555557788888888766 78889


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.+|.+++...
T Consensus       344 ~~a~~~l~~l~~~~  357 (521)
T 5TBK_D          344 KEAVWFLSNITAGN  357 (521)
T ss_dssp             HHHHHHHHHHTTSC
T ss_pred             HHHHHHHHHHhCCC
Confidence            99999999988653


No 104
>4U2X_F eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=97.37  E-value=1.2e-07  Score=83.04  Aligned_cols=116  Identities=17%  Similarity=0.149  Sum_probs=79.8  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~  324 (747)
                      +++.+..++.+.++.++..+++++.++..........+...++++.+..++.+.++.++..++.++..++.. .......
T Consensus         9 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   88 (175)
T 4U2X_F            9 ALPCLLHLLSSPKESIRKEACWTVSNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRY   88 (175)
T ss_dssp             CSHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHH
T ss_pred             hHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChHHHHHHHHHhCCHHHHHHHHHHHHHHhcCCCHHHHHH
Confidence            445566666666778889999999998865443333444446777888877776778888899999988753 2222233


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...+.++.+...+. ..++.++..++.++.+++....
T Consensus        89 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~  125 (175)
T 4U2X_F           89 LVALGCIKPLCDLLT-VMDSKIVQVALNGLENILRLGE  125 (175)
T ss_dssp             HHHHTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcch
Confidence            333456777777776 5566788888888888877543


No 105
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=97.37  E-value=1.2e-07  Score=87.00  Aligned_cols=113  Identities=25%  Similarity=0.271  Sum_probs=78.0  Template_Neff=12.900

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+.
T Consensus        10 ~~~~~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   89 (247)
T 4V3Q_A           10 LPQMVQQLNSPDQQELQSALRKLSQIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVI   89 (247)
T ss_dssp             HHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHhcCCCHHHHHHHHHHHHHHHcCChhhhhhhhccCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcHHHHHHHH
Confidence            34455566677788888899999888765444444444556778888888777778888999999988765443333333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ..++++.+...+. +.++.++..++.++..++..
T Consensus        90 ~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  122 (247)
T 4V3Q_A           90 DAGALPALVQLLS-SPNEQILQEALWTLGNIASG  122 (247)
T ss_dssp             HTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            4456777777776 45667777788888777753


No 106
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=97.34  E-value=1.5e-07  Score=97.01  Aligned_cols=136  Identities=21%  Similarity=0.259  Sum_probs=84.7  Template_Neff=12.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE-SAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~-~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+..++...++.++..++.+|.+++.... .....+...++++.+..++. ..+..++..++.++.+++.......
T Consensus       243 ~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  322 (458)
T 3NMZ_A          243 GCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENK  322 (458)
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCChhHHHHHHHCCHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCchhH
Confidence            456667777777777888999999999887543 22334444567777888777 5567788889999999886433333


Q NP_000290.2     323 LETRR-QNGIREAVSLLRR---TGNAEIQKQLTGLLWNLSS----TDELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       323 ~~ll~-~~IL~~Ll~lL~s---s~d~eVr~~AL~aLsnLas----~~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..+.. .+.++.+..++..   ..+..++..++.++.+++.    .......+.+ ++++.|+.++.
T Consensus       323 ~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~  389 (458)
T 3NMZ_A          323 ADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLK  389 (458)
T ss_pred             HHHHHhcChHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhC
Confidence            33333 4566666666641   1234566677777766652    2222222333 56666666654


No 107
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=97.34  E-value=1.6e-07  Score=102.08  Aligned_cols=377  Identities=16%  Similarity=0.154  Sum_probs=185.5  Template_Neff=11.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.|+.++.+.+..++..++.+|.+++.. .......+...+.++.++.++.. .+..++..++.+|.+++.... ...
T Consensus        91 ~i~~Lv~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~L~~ll~~~~~~~v~~~a~~~L~~L~~~~~-~~~  169 (584)
T 3L6X_A           91 GIPVLVGLLDHPKKEVHLGACGALKNISFGRDQDNKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDS-IKM  169 (584)
T ss_dssp             HHHHHHHGGGCSSHHHHHHHHHHHHHHTSSSCHHHHHHHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHTTSGG-GHH
T ss_pred             cHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCCHHHHHHHHcCChHHHHHHHHHHcCCHHHHHHHHHHHHHHhcCHH-HHH
Confidence            466677777777788999999999999874 34444445556778888888875 366788888999988875432 222


Q NP_000290.2     324 ETRRQNGIREAVSLLR-----------------RTGNAEIQKQLTGLLWNLSSTDE-LKEELIA--DALPVLADRVIIPF  383 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~-----------------ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve--giLe~Lv~LL~~~~  383 (747)
                      .+... .+..+...+.                 ...+..++..++.+|.+++.... ....+..  ++++.|+.+|....
T Consensus       170 ~l~~~-~l~~L~~~l~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~L~~l~~~~~~~~~~l~~~~g~v~~L~~~l~~~~  248 (584)
T 3L6X_A          170 EIVDH-ALHALTDEVIIPHSGWEREPNEDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEI  248 (584)
T ss_dssp             HHHHH-THHHCCCCCCHHHHCCC----------CCCCHHHHHHHHHHHHHHTSSCHHHHHHHHHSTTHHHHHHHHHHHHH
T ss_pred             HHHHH-HHHHHHHhccccCCCCCCCCCcCCCCcccChHHHHHHHHHHHHHHhcCCHHHHHHHHhCCCHHHHHHHHHHHHh
Confidence            22222 4444444431                 12235677888899998887542 3333333  67788888876432


Q NP_000290.2     384 SGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMR--E------LLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLM  455 (747)
Q Consensus       384 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  455 (747)
                      ..          ...++++.-++..+|+.-..-.  +      .....+.-....+   .....++..+. -.+.++.|.
T Consensus       249 ~~----------~~~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~~~~~~~---~~~~~~~~~l~-~~~~~~~l~  314 (584)
T 3L6X_A          249 GQ----------KDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTG---TSPARGYELLF-QPEVVRIYI  314 (584)
T ss_dssp             HT----------TCCSCHHHHHHHHHHHHHHTTHHHHSTTCCC-----------------CCCCGGGGGG-SHHHHHHHH
T ss_pred             cC----------CCCChHHHHHHHHHHHHHHhhhhccChhHHHHHHhcCcCCCCCC---CCChhhhhHhh-ChhHHHHHH
Confidence            10          0123334444444443211100  0      0000000000000   00111122221 134555555


Q NP_000290.2     456 AYVQNCVAASRCDDKSVENCMCVLHNLSYRLD---AEVPTRYRQLEYNAR----------NAYTEKSSTGCFSNKSDKMM  522 (747)
Q Consensus       456 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~---~~~~~~~~~~~~~~~----------~~~~~~~~~~~~~~~~~~~~  522 (747)
                      ..+...     -+..-.+.+..+|.||+..-.   .++....+  +...-          +.........+..|-+.   
T Consensus       315 ~ll~~~-----~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~--~~~~l~~L~~ll~~~~~~v~~~a~~~L~~L~~---  384 (584)
T 3L6X_A          315 SLLKES-----KTPAILEASAGAIQNLCAGRWTYGRYIRSALR--QEKALSAIADLLTNEHERVVKAASGALRNLAV---  384 (584)
T ss_dssp             HHHHHC-----CCHHHHHHHHHHHHHHHSSCSHHHHHHHHHHT--SHHHHHHHHHGGGCSCHHHHHHHHHHHHHHHT---
T ss_pred             HHHHcC-----CCHHHHHHHHHHHHHHhCCCccCCHHHHHHHH--HcChHHHHHHHhcCCCHHHHHHHHHHHHHHhc---
Confidence            554431     144556777888888876321   11111000  00000          00001111111111100   


Q NP_000290.2     523 NNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSK--------KDATLEACAGALQNLTASKGLMSSGMSQLIGLKE  594 (747)
Q Consensus       523 ~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~--------d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~  594 (747)
                                   +...... +..++++.|+.+|.. .        +..++..++.+|.+++.....     ....+.+.
T Consensus       385 -------------~~~~~~~-l~~~~l~~L~~~L~~-~~~~~~~~~~~~~~~~~l~~L~~l~~~~~~-----~~~~l~~~  444 (584)
T 3L6X_A          385 -------------DARNKEL-IGKHAIPNLVKNLPG-GQQNSSWNFSEDTVISILNTINEVIAENLE-----AAKKLRET  444 (584)
T ss_dssp             -------------TCSCHHH-HHHHHHHHHHHTSSS-SSCSGGGTCCHHHHHHHHHHHHHHHTTCHH-----HHHHHHHT
T ss_pred             -------------ChHHHHH-HHcchHHHHHHcCCC-CCCCCCcCCCHHHHHHHHHHHHHHHhcCHH-----HHHHHHHC
Confidence                         0011111 224788888888863 3        334467888888888764332     23444577


Q NP_000290.2     595 KGLPQIARLLQSG--NSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPE-VTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       595 giI~~Ll~LL~s~--d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~-Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ++++.|+.++...  +..++..|+.+|.+++..... ..+...++++. +..++...    ..++.++..++.+|.++..
T Consensus       445 ~~l~~L~~ll~~~~~~~~v~~~a~~~L~~l~~~~~~~~~l~~~g~~~~~l~~~~~~~----~~~~~~~~~a~~~L~~l~~  520 (584)
T 3L6X_A          445 QGIEKLVLINKSGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNA----SRSQSSHSYDDSTLPLIDR  520 (584)
T ss_dssp             THHHHHHHHHTCSSSCHHHHHHHHHHHHHHHTSHHHHHHHHTTTCCGGGGCCC---------------------------
T ss_pred             CHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCHHHHHHHHHcCCchhhceeccccc----ccCCCCCCcccccccccCC
Confidence            8999999998753  477899999999999876444 33445566676 55553211    0357788889999999987


Q NP_000290.2     671 SQ  672 (747)
Q Consensus       671 ~s  672 (747)
                      ..
T Consensus       521 ~~  522 (584)
T 3L6X_A          521 NQ  522 (584)
T ss_dssp             --
T ss_pred             CC
Confidence            53


No 108
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=97.33  E-value=1.5e-07  Score=85.77  Aligned_cols=113  Identities=20%  Similarity=0.252  Sum_probs=78.4  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++.+++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (243)
T 5MFI_B            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL   84 (243)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHTTTSSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666777888899999998876544443444445677888888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ...++++.+...+. ..++.++..++.++..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  117 (243)
T 5MFI_B           85 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIAS  117 (243)
T ss_dssp             HHTTCHHHHHHHTS-SSCHHHHHHHHHHHHHHTT
T ss_pred             HHcCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHc
Confidence            33456777777775 4566677777888877775


No 109
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=97.33  E-value=1.5e-07  Score=85.77  Aligned_cols=113  Identities=20%  Similarity=0.252  Sum_probs=77.5  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++.+++.........+
T Consensus         5 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~   84 (243)
T 5MFJ_B            5 ELPQMVQQLNSPDQQELQSALRKLSQIASGGNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL   84 (243)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGGCSCTTTC-CHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHHcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666777888899999998876544443444445677888888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ...++++.+...+. ..++.++..++.++..++.
T Consensus        85 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  117 (243)
T 5MFJ_B           85 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIAS  117 (243)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHT
T ss_pred             HHcCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHc
Confidence            33456777777775 4566677777888877775


No 110
>5VOZ_P V-type proton ATPase catalytic subunit; V-ATPase, SidK, rotational state 3;{Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.30  E-value=2.1e-07  Score=101.03  Aligned_cols=134  Identities=14%  Similarity=0.103  Sum_probs=89.5  Template_Neff=8.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICK--LVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~--Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .++.++.++.+ +..++..++.+|..++... .........+.++.  ++.++.. .+..++..++.+|..++... ...
T Consensus       124 ~~~~li~lL~~-d~~i~~~a~~~L~~L~~~~-~~~~~~~~~~~l~~~~li~~L~~~~~~~~~~~a~~~L~~L~~~~-~~r  200 (478)
T 5VOZ_P          124 LEQLFDVSLKG-DFQTVLISGFNVVSLLVQN-GLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIP-EYR  200 (478)
T ss_dssp             HHHHTTSTTSS-CHHHHHHHHHHHHHHHTSS-SCCCHHHHHHHHSSHHHHHHHHCSSCHHHHHHHHHHHHHHTTSH-HHH
T ss_pred             HHHHHHHHcCC-CHHHHHHHHHHHHHHHHhc-cccCcccchhhcccchHHHHHhccCCccHHHHHHHHHHHHcCCh-HHH
Confidence            45666667766 6677888888888887643 22112223456666  7777753 35667888899999888643 333


Q NP_000290.2     323 LETRR--QNGIREAVSLLRRT----------------GNAEIQKQLTGLLWNLSSTDELKEELIA---DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~--~~IL~~Ll~lL~ss----------------~d~eVr~~AL~aLsnLas~~~~~~~Lve---giLe~Lv~LL~~  381 (747)
                      ..+..  .+.++.|+.++...                .++.++..++.++..|+........+..   ++++.|+++++.
T Consensus       201 ~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~~~~~~~~l~~~~~~~i~~Lv~ll~~  280 (478)
T 5VOZ_P          201 DVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKI  280 (478)
T ss_dssp             HHHHHSTTSSHHHHHHHHHHHHHSCSSCCCTTTSSSHHHHHHHHHHHHHHHHHTTSHHHHHHHHHHSHHHHGGGHHHHHH
T ss_pred             HHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhcCHHHHHHHHHHhHHHHHHHHHHHhc
Confidence            33444  35777888877621                2567888899999999876555555543   688889998886


Q NP_000290.2     382 P  382 (747)
Q Consensus       382 ~  382 (747)
                      .
T Consensus       281 ~  281 (478)
T 5VOZ_P          281 T  281 (478)
T ss_dssp             C
T ss_pred             c
Confidence            4


No 111
>5D80_H V-type proton ATPase catalytic subunit; Hydrolase, Autoinhibition; 6.202A {Saccharomyces cerevisiae}
Probab=97.30  E-value=2.1e-07  Score=101.03  Aligned_cols=134  Identities=14%  Similarity=0.103  Sum_probs=89.5  Template_Neff=8.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICK--LVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~--Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .++.++.++.+ +..++..++.+|..++... .........+.++.  ++.++.. .+..++..++.+|..++... ...
T Consensus       124 ~~~~li~lL~~-d~~i~~~a~~~L~~L~~~~-~~~~~~~~~~~l~~~~li~~L~~~~~~~~~~~a~~~L~~L~~~~-~~r  200 (478)
T 5D80_H          124 LEQLFDVSLKG-DFQTVLISGFNVVSLLVQN-GLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIP-EYR  200 (478)
T ss_pred             HHHHHHHHcCC-CHHHHHHHHHHHHHHHHhc-cccCcccchhhcccchHHHHHhccCCccHHHHHHHHHHHHcCCh-HHH
Confidence            45666667766 6677888888888887643 22112223456666  7777753 35667888899999888643 333


Q NP_000290.2     323 LETRR--QNGIREAVSLLRRT----------------GNAEIQKQLTGLLWNLSSTDELKEELIA---DALPVLADRVII  381 (747)
Q Consensus       323 ~~ll~--~~IL~~Ll~lL~ss----------------~d~eVr~~AL~aLsnLas~~~~~~~Lve---giLe~Lv~LL~~  381 (747)
                      ..+..  .+.++.|+.++...                .++.++..++.++..|+........+..   ++++.|+++++.
T Consensus       201 ~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~~~~~~~~l~~~~~~~i~~Lv~ll~~  280 (478)
T 5D80_H          201 DVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVKI  280 (478)
T ss_pred             HHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhcCHHHHHHHHHHhHHHHHHHHHHHhc
Confidence            33444  35777888877621                2567888899999999876555555543   688889998886


Q NP_000290.2     382 P  382 (747)
Q Consensus       382 ~  382 (747)
                      .
T Consensus       281 ~  281 (478)
T 5D80_H          281 T  281 (478)
T ss_pred             c
Confidence            4


No 112
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=97.29  E-value=1.9e-07  Score=95.60  Aligned_cols=138  Identities=25%  Similarity=0.275  Sum_probs=87.6  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR--SPNQNVQQAAAGALRNLVFRSTTN-  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~--s~d~eVr~~AL~aLs~La~~~~~~-  321 (747)
                      .+++.+...+.+.+..++..++.++..++.........+...+.++.+...+.  ..++.++..++.++..++...... 
T Consensus       266 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~  345 (529)
T 1JDH_A          266 GLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAE  345 (529)
T ss_dssp             HHHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTHHHHHHHHHHHHTTCHHHHHHHHHHHHHHTSSSTTHH
T ss_pred             hHHHHHHHHhCCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHcCHHHHHHHHHHhcCCChHhHHHHHHHHHHHhcCcccHH
Confidence            44555666666667778888888888887654433333344556666766554  345677888888888887654321 


Q NP_000290.2     322 --KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVIIP  382 (747)
Q Consensus       322 --~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~~  382 (747)
                        .......+.++.+...+....++.++..++.++.+++........+.. ++++.|..++...
T Consensus       346 ~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~l~~~l~~~  409 (529)
T 1JDH_A          346 MAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRA  409 (529)
T ss_dssp             HHHHHHHHTTCHHHHHHTTSTTCCHHHHHHHHHHHHHHTTSGGGHHHHHHTTHHHHHHHHHHHH
T ss_pred             HHHHHHHhcccHHHHHHHHCCCCCHHHHHHHHHHHHHHhcChhhhHHHHhcCHHHHHHHHHHhc
Confidence              112222356667777775223567888899999988876444444444 6777777777643


No 113
>2Z6G_A B-catenin; Full-Length, Beta-Catenin, CELL ADHESION; 3.4A {Danio rerio}
Probab=97.28  E-value=2.2e-07  Score=105.08  Aligned_cols=353  Identities=20%  Similarity=0.229  Sum_probs=182.2  Template_Neff=10.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+..++.+.+..++..++.+|..++.........+...+++..++.++... +..++..++.+|..+..... ...
T Consensus       276 ~~~~~L~~lL~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~~v~~~a~~~L~~l~~~~~-~~~  354 (780)
T 2Z6G_A          276 GGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSS-NKP  354 (780)
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHhCCHH-HHH
Confidence            3455566666666778888888888888764443333333445677777777654 56777888888888775432 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      .+...++++.+...+. ..+..++..++.+|..++...... ....++++.|+.++...                ++++.
T Consensus       355 ~~~~~~~l~~L~~~l~-~~~~~v~~~al~~L~~l~~~~~~~-~~~~~~l~~L~~~l~~~----------------~~~v~  416 (780)
T 2Z6G_A          355 AIVEAGGMQALGLHLT-DPSQRLVQNCLWTLRNLSDAATKQ-EGMEGLLGTLVQLLGSD----------------DINVV  416 (780)
T ss_pred             HHHHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHhcCCCCH-HHHcChHHHHHHHhcCC----------------CHHHH
Confidence            2333456777777776 556778888999998887643321 11125566666666421                23344


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..+|..-..-      .+.              .+. .-.-.+.++.|...+..    ..-+..-.+.+.+.|.++.
T Consensus       417 ~~a~~~L~~l~~~------~~~--------------~~~-~~~~~~~l~~L~~~l~~----~~~~~~v~~~a~~~L~~l~  471 (780)
T 2Z6G_A          417 TCAAGILSNLTCN------NYK--------------NKM-MVCQVGGIEALVRTVLR----AGDREDITEPAICALRHLT  471 (780)
T ss_pred             HHHHHHHHHHHcC------CHH--------------HHH-HHHHCChHHHHHHHHhc----CCCCHHHHHHHHHHHHHHH
Confidence            4444443221100      000              000 00012233333322211    0112233456666666666


Q NP_000290.2     484 YRLDAEV------------PTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRT  551 (747)
Q Consensus       484 ~~~~~~~------------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~  551 (747)
                      .+.....            +.-.+-+.. ..+....+....++.+-..                .......+.+.++++.
T Consensus       472 ~~~~~~~~~~~~~~~~~~i~~L~~ll~~-~~~~~v~~~a~~~L~~l~~----------------~~~~~~~~~~~~~l~~  534 (780)
T 2Z6G_A          472 SRHQDAEMAQNAVRLHYGLPVVVKLLHP-PSHWPLIKATVGLIRNLAL----------------CPANHAPLREQGAIPR  534 (780)
T ss_pred             cCCccHHHHHHHHHHCCcHHHHHHHhcC-CCCHHHHHHHHHHHHHHhc----------------CHHHHHHHHhCChHHH
Confidence            5442110            000000000 0000000011111111100                0011112345566666


Q NP_000290.2     552 YLNLMGKSKK----------------------DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS  609 (747)
Q Consensus       552 LL~LL~ss~d----------------------~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~  609 (747)
                      |+.++.. ..                      ..++..++.+|.+++....      ....+...++++.|+.++.+.++
T Consensus       535 L~~ll~~-~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~aL~~L~~~~~------~~~~~~~~~~l~~L~~~l~~~~~  607 (780)
T 2Z6G_A          535 LVQLLVR-AHQDTQRRTSMGGTQQQFVEGVRMEEIVEACTGALHILARDIH------NRIVIRGLNTIPLFVQLLYSPIE  607 (780)
T ss_pred             HHHHhcC-CCHHHHHHHHhhhhhhhhhcCCChHHHHHHHHHHHHHHhCChh------HHHHHHhCCcHHHHHHHhcCCCH
Confidence            7666652 22                      2366777777777775422      12222345667777777777677


Q NP_000290.2     610 DVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       610 eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      .++..++.+|.+++..... ..+...++++.|..++.+      .++.++..++.+|.+|+..
T Consensus       608 ~v~~~a~~~L~~l~~~~~~~~~~~~~~~i~~L~~ll~~------~~~~v~~~a~~~L~~L~~~  664 (780)
T 2Z6G_A          608 NIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHS------RNEGVATYAAAVLFRMSED  664 (780)
T ss_pred             HHHHHHHHHHHHHhcCHHHHHHHHHCCcHHHHHHHhcC------CCHHHHHHHHHHHHHHHCC
Confidence            7788888888888755332 233345566777777665      3567777788888887764


No 114
>1HO8_A VACUOLAR ATP SYNTHASE SUBUNIT H; HEAT repeat, HYDROLASE; 2.95A {Saccharomyces cerevisiae} SCOP: a.118.1.9
Probab=97.27  E-value=2.5e-07  Score=100.53  Aligned_cols=135  Identities=14%  Similarity=0.099  Sum_probs=89.8  Template_Neff=8.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICK--LVDLLRS-PNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~--Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ..++.++.++.+ +..++..++.+|..++... .........+.++.  ++.++.. .+..++..++.+|..++... ..
T Consensus       125 ~~~~~li~lL~~-d~~i~~~a~~~L~~L~~~~-~~~~~~~~~~~l~~~~lv~~L~~~~~~~~~~~a~~~L~~L~~~~-~~  201 (480)
T 1HO8_A          125 QLEQLFDVSLKG-DFQTVLISGFNVVSLLVQN-GLHNVKLVEKLLKNNNLINILQNIEQMDTCYVCIRLLQELAVIP-EY  201 (480)
T ss_dssp             HHHHHHHHCSCS-SHHHHHHHHHHHHHHHTST-TTCCHHHHHHHHHCHHHHHHHHCTTCHHHHHHHHHHHHHHHTSH-HH
T ss_pred             hHHHHHHHHcCC-CHHHHHHHHHHHHHHHHhc-cccCcccchhhcccchHHHHHhcccCccHHHHHHHHHHHHcCCh-HH
Confidence            345666777766 6677888888888887643 22112223456776  7777753 35667888899998888643 33


Q NP_000290.2     322 KLETRR--QNGIREAVSLLRRT----------------GNAEIQKQLTGLLWNLSSTDELKEELIA---DALPVLADRVI  380 (747)
Q Consensus       322 ~~~ll~--~~IL~~Ll~lL~ss----------------~d~eVr~~AL~aLsnLas~~~~~~~Lve---giLe~Lv~LL~  380 (747)
                      ...+..  .+.++.|+.++...                .++.++..++.++..|.........+..   ++++.|+++++
T Consensus       202 r~~~~~~~~~~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~~~~~~~~i~~~~~~~i~~Lv~ll~  281 (480)
T 1HO8_A          202 RDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTFNPVFANELVQKYLSDFLDLLKLVK  281 (480)
T ss_dssp             HHHHHTTHHHHHHHHHHHHHHHHC-------------CCHHHHHHHHHHHHHHHTTSHHHHHHHHTTSHHHHHHHHHHHH
T ss_pred             HHHHHHccccchHHHHHHHHhccccchhcchhhccCcCCCHHHHHHHHHHHHHHhcCHHHHHHHHHHhHHHHHHHHHHHh
Confidence            333444  35677787777621                2567888899999998876555555543   68888999888


Q NP_000290.2     381 IP  382 (747)
Q Consensus       381 ~~  382 (747)
                      ..
T Consensus       282 ~~  283 (480)
T 1HO8_A          282 IT  283 (480)
T ss_dssp             HC
T ss_pred             hc
Confidence            64


No 115
>6S9O_F designed Armadillo repeat protein with; peptide binder, repeat protein, designed; HET: CA, EDO; 3.17A {synthetic construct}
Probab=97.21  E-value=2.9e-07  Score=88.31  Aligned_cols=135  Identities=25%  Similarity=0.275  Sum_probs=88.9  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..+..........+...++++.+...+...++.++..++.++..++..........
T Consensus       173 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  252 (344)
T 6S9O_F          173 ALPALVQLLSSPNEQILQLALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  252 (344)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCChHHHHHHHhcChHHHHHHHccCCCHHHHHHHHHHHHHHHcCcHHHHHHH
Confidence            45556666666677888889999988876543333333334567777777777777888889999988875544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVII  381 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~~  381 (747)
                      ...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.|..++..
T Consensus       253 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  309 (344)
T 6S9O_F          253 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSH  309 (344)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGC
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHhhC
Confidence            34456777777776 55677888899999988865322 222222 566666666643


No 116
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=97.20  E-value=3.2e-07  Score=93.10  Aligned_cols=114  Identities=15%  Similarity=0.165  Sum_probs=77.3  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP------NQNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~------d~eVr~~AL~aLs~La~~~~  319 (747)
                      +++.+..++.+.++.++..++.+|.+++... .....+ ...+++.+..++...      +..++..++.++.+++...+
T Consensus       332 ~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~-~~~~~~-~~~~~~~l~~~l~~~~~~~~~~~~~~~~a~~~L~~l~~~~~  409 (457)
T 1XM9_A          332 GLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LLHRVM-GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  409 (457)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHHTSG-GGHHHH-HHHTHHHHHHTTTSCCSCSTTHHHHHHHHHHHHHHHHTTCT
T ss_pred             hHHHHHHHHhcCCHHHHHHHHHHHHHHhcCH-HHHHHH-HcccHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHhcCH
Confidence            4556666676677788889999999988542 222222 234667777777655      57788888999988875444


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD  361 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~  361 (747)
                      .....+...+.++.+..++....++.++..++.++..++...
T Consensus       410 ~~~~~~~~~~~~~~l~~ll~~~~~~~v~~~a~~~L~~l~~~~  451 (457)
T 1XM9_A          410 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  451 (457)
T ss_dssp             HHHHHHCCHHHHHHHHHHHHCTTCHHHHHHHHHHHHTTSSST
T ss_pred             HHHHHHHhccHHHHHHHHHhCCCCHHHHHHHHHHHHHHhhcH
Confidence            444444455677778887762256778888888888887644


No 117
>1XQS_B HSPBP1 protein, Heat shock 70; armadillo repeat, superhelical twist, CHAPERONE; HET: AMP; 2.9A {Homo sapiens} SCOP: a.118.1.21
Probab=97.20  E-value=3.3e-07  Score=87.92  Aligned_cols=134  Identities=22%  Similarity=0.180  Sum_probs=90.6  Template_Neff=11.900

Q NP_000290.2     246 TIPKAVQ-YLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~-lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.++. ++.+.+..++..++.++.+++.........+...++++.+..++... +..++..++.++.+++........
T Consensus        66 ~i~~l~~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~  145 (280)
T 1XQS_B           66 GMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLL  145 (280)
T ss_dssp             HHHHCCCCCTSCSCHHHHHHHHHHHHHHHTTCHHHHHHHHTTTHHHHHHHHHHSCSCHHHHHHHHHHHHHTTSSCHHHHH
T ss_pred             cHHHHHHHHhhcCCHHHHHHHHHHHHHHccCCHHHHHHHHHCCHHHHHHHHhccCCCHHHHHHHHHHHHHHHhcCHHHHH
Confidence            3455555 66666677888899999998865444344444456777788877765 677888899999998865443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      .+...+.++.+..++. ..+..++..++.++.+++.... ....+.. ++++.|+.++.
T Consensus       146 ~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  203 (280)
T 1XQS_B          146 QFLRLDGFSVLMRAMQ-QQVQKLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVR  203 (280)
T ss_dssp             HHHTTTHHHHHHHHHT-SSCHHHHHHHHHHHHHHHHHCGGGHHHHHTTTHHHHHHHHHT
T ss_pred             HHHHCCHHHHHHHHhh-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHHHHHHHc
Confidence            3444466777777776 4566788889999998887543 3333333 67777777764


No 118
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=97.18  E-value=3.4e-07  Score=83.37  Aligned_cols=134  Identities=19%  Similarity=0.243  Sum_probs=88.0  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (243)
T 5MFI_B           47 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  126 (243)
T ss_dssp             CHHHHHHTTTSSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHTSSSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666766777888889999998886544433334445677778888877777888889999998876444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (243)
T 5MFI_B          127 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLD  182 (243)
T ss_dssp             HHTTCHHHHHHTTT-SSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHcc
Confidence            44456777777776 5566778888888888876322 2222222 45666665554


No 119
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=97.18  E-value=3.4e-07  Score=83.37  Aligned_cols=134  Identities=19%  Similarity=0.243  Sum_probs=87.2  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (243)
T 5MFJ_B           47 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  126 (243)
T ss_dssp             CHHHHHHGGGCSCTTTC-CHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666766777888889999998886544433334445677778888877777888889999998876444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (243)
T 5MFJ_B          127 IEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLD  182 (243)
T ss_dssp             HHTTCHHHHHHTTT-SSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHcc
Confidence            44456777777776 5566778888888888876322 2222222 45666665554


No 120
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=97.16  E-value=3.9e-07  Score=91.03  Aligned_cols=134  Identities=25%  Similarity=0.292  Sum_probs=90.1  Template_Neff=12.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+..++...++.++..++.++.+++.........+
T Consensus       200 ~i~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  279 (397)
T 6SA6_A          200 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  279 (397)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHcCCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHH
Confidence            45566667776777888899999999887544444444455678888888887788889999999999876443333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++.+++..... ...+.. ++++.|+.++.
T Consensus       280 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  335 (397)
T 6SA6_A          280 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLS  335 (397)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HhCChHHHHHHHhc-CCcHHHHHHHHHHHHHHhcCcHHHHHHHHhcChHHHHHHHhc
Confidence            34456777777776 45667778888888888654322 222222 56666666654


No 121
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=97.16  E-value=4e-07  Score=98.84  Aligned_cols=135  Identities=26%  Similarity=0.299  Sum_probs=93.7  Template_Neff=11.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++.+++...+.....+...+.++.+...+.+.+..++..++.++..++.........
T Consensus       220 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  299 (671)
T 6SA8_A          220 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQA  299 (671)
T ss_dssp             THHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             ChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCcHHHHH
Confidence            34566667777777888999999999987654443334444567788888887777888899999999888654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELK-EELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~-~~Lve-giLe~Lv~LL~  380 (747)
                      +...++++.+...+. ..++.++..++.++..++...... ..+.. ++++.|..++.
T Consensus       300 ~~~~~~~~~L~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~l~~l~~~l~  356 (671)
T 6SA8_A          300 VIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  356 (671)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHHhChHHHHHHHhc-CCcHHHHHHHHHHHHHHhcCCcHHHHHHHhcChHHHHHHHhc
Confidence            444567778888886 556788889999999987643322 22333 66777777775


No 122
>1XQR_A HspBP1 protein; armadillo repeat, superhelical twist, CHAPERONE; HET: MSE; 2.1A {Homo sapiens} SCOP: a.118.1.21
Probab=97.14  E-value=4.4e-07  Score=88.91  Aligned_cols=134  Identities=22%  Similarity=0.180  Sum_probs=91.0  Template_Neff=11.300

Q NP_000290.2     246 TIPKAVQ-YLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~-lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.++. ++...++.++..++.+|.+++.........+...++++.+..++... +..++..++.++.+++........
T Consensus        82 ~~~~l~~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~l~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~  161 (296)
T 1XQR_A           82 GMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLL  161 (296)
T ss_dssp             HHHHCCCCCTTCSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCSCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             cHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCHHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHH
Confidence            3455555 66666677888899999998865443334444456777788777765 677888999999999865443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      .+...+.++.+...+. ..+..++..++.++.+++.... ....+.. ++++.|+.++.
T Consensus       162 ~~~~~~~i~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~L~~ll~  219 (296)
T 1XQR_A          162 QFLRLDGFSVLMRAMQ-QQVQKLKVKSAFLLQNLLVGHPEHKGTLCSMGMVQQLVALVR  219 (296)
T ss_dssp             HHHHTTHHHHHHHHHH-SSCHHHHHHHHHHHHHHHHHCGGGHHHHHHTTHHHHHHHHHT
T ss_pred             HHHHCCHHHHHHHHhh-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCCHHHHHHHHHc
Confidence            3444456777777776 4567788889999999887543 3333333 67777777764


No 123
>4UAD_A Importin alpha import adaptor, Influenza; importin karyopherin complex NLS, PROTEIN; 2.42A {Homo sapiens}
Probab=97.13  E-value=4.5e-07  Score=91.78  Aligned_cols=368  Identities=15%  Similarity=0.162  Sum_probs=225.0  Template_Neff=12.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE--SAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~--~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      .+++.+...+.+.++.++..++.+|..+.....  .....+...++++.+...+.. .++.++..++.++..++......
T Consensus        23 ~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~  102 (479)
T 4UAD_A           23 VITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQ  102 (479)
T ss_dssp             CCCHHHHHHHTSSCHHHHHHHHHHHHHHHTCSSSCCHHHHHHSTTHHHHHHHHTTCTTCHHHHHHHHHHHHHHTTSCHHH
T ss_pred             hhHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCCCChhHhhcCcchHHHHHHHhhcCCCHHHHHHHHHHHHHHhCCCchH
Confidence            456666777777778889999999988876422  111122223567777777765 66778888999998887654333


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVD  399 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~  399 (747)
                      ...+...++++.+..++. ..++.++..++.++..++.... ....+.. ++++.|+.++...               .+
T Consensus       103 ~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~---------------~~  166 (479)
T 4UAD_A          103 TKIVIEAGAVPIFIELLN-SDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKS---------------TR  166 (479)
T ss_dssp             HHHHHHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHC---------------CC
T ss_pred             HHHHHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChHHHHHHHhCCcHHHHHHHhhcC---------------Cc
Confidence            333333457777788776 5567888899999998887533 2223333 5666666666521               12


Q NP_000290.2     400 PEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVL  479 (747)
Q Consensus       400 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  479 (747)
                      +++-..+..+|..-..                     ............+.++.|...+..      -+..-...+...|
T Consensus       167 ~~~~~~a~~~l~~l~~---------------------~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l  219 (479)
T 4UAD_A          167 LTMTRNAVWALSNLCR---------------------GKNPPPEFAKVSPCLPVLSRLLFS------SDSDLLADACWAL  219 (479)
T ss_dssp             HHHHHHHHHHHHHHHC---------------------CCSSCCCGGGTGGGHHHHHHHTTC------CCHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHc---------------------CCCCCchhhcccchHHHHHHHhcC------CCHHHHHHHHHHH
Confidence            3333333333321110                     000011111122334433333321      1111222233333


Q NP_000290.2     480 HNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKS  559 (747)
Q Consensus       480 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss  559 (747)
                      .++....                                                  ......+.+.++++.++.++. +
T Consensus       220 ~~l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~  248 (479)
T 4UAD_A          220 SYLSDGP--------------------------------------------------NEKIQAVIDSGVCRRLVELLM-H  248 (479)
T ss_dssp             HHHTSSS--------------------------------------------------HHHHHHHHHTTCHHHHHHGGG-C
T ss_pred             HHHhcCc--------------------------------------------------hHHHHHHHhCCHHHHHHHHhc-C
Confidence            3322100                                                  000111234567788888887 4


Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVF  637 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI  637 (747)
                      .++.++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++... .. ..+...+++
T Consensus       249 ~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~  323 (479)
T 4UAD_A          249 NDYKVASPALRAVGNIVTGDDI-----QTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIF  323 (479)
T ss_dssp             SCHHHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCH
T ss_pred             CCHHhHHHHHHHHHHHhcCCHH-----HHHHHHhcChHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHH
Confidence            6778888999999998875332     1223334578888999998888889999999999998763 22 233445678


Q NP_000290.2     638 PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS-QPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       638 ~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~-s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.+..++.+      .++.++..++.+|.+++.. .+.....+.+.++++.+..++.+. ++.++..++.+|.+++...+
T Consensus       324 ~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~~~  396 (479)
T 4UAD_A          324 PVLIEILQK------AEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVM-DSKIVQVALNGLENILRLGE  396 (479)
T ss_dssp             HHHHHHHHH------SCHHHHHHHHHHHHHHHHHSCHHHHHHHHHTTCHHHHHGGGGCS-CHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhc------cCHHHHHHHHHHHHHHHcCCCHHHHHHHHHcCcHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHHH
Confidence            888888876      3678899999999999864 233444455556788888888866 78889999999999987654


Q NP_000290.2     717 LQ  718 (747)
Q Consensus       717 ~~  718 (747)
                      ..
T Consensus       397 ~~  398 (479)
T 4UAD_A          397 QE  398 (479)
T ss_dssp             HH
T ss_pred             Hh
Confidence            43


No 124
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=97.07  E-value=6.1e-07  Score=84.84  Aligned_cols=114  Identities=25%  Similarity=0.284  Sum_probs=75.6  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..+...........
T Consensus        89 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  168 (328)
T 5MFD_C           89 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  168 (328)
T ss_dssp             HHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888999988876543333333344567777777777777888889999988875443332333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..+..++..++.++..++..
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  202 (328)
T 5MFD_C          169 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASG  202 (328)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTS
T ss_pred             HHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            33456666777775 45566777777777777653


No 125
>6HB3_B Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 3.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=97.07  E-value=7e-07  Score=92.28  Aligned_cols=121  Identities=9%  Similarity=-0.026  Sum_probs=77.4  Template_Neff=10.100

Q NP_000290.2     246 TIPKAVQYLSS---QDEKYQAIGAYYIQHTCFQDESAKQQVY--QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       246 iL~~Ll~lL~s---sd~eVr~sAL~aLsnLs~~~~~~~~~li--~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      .++.|+.++..   .+..++..++.+|.++... ......+.  ..+.++.++.++...+..++..++.+|.+++.... 
T Consensus        52 ~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~-~~~~~~l~~~~~g~i~~L~~ll~~~~~~~~~~a~~~L~nl~~~~~-  129 (369)
T 6HB3_B           52 PIKDIIKMIMDPEHGTRVIIQQGVTILVNLSED-KLVRNIILSDDKKFLKFLVWKIVDLTNPNADIMCILLSNLAKDDG-  129 (369)
T ss_pred             cHHHHHHHHhCCCCCCHHHHHHHHHHHHHHcCC-HHHHHHHHhccCCcHHHHHHHhcCCCHHHHHHHHHHHHHHcCChH-
Confidence            56667777743   3567888899999998754 33344444  56788888888877667788888999988886432 


Q NP_000290.2     321 NKLET-------------------------RRQNGIREAVSLLRRTG------NAEIQKQLTGLLWNLSSTDELKEELIA  369 (747)
Q Consensus       321 ~~~~l-------------------------l~~~IL~~Ll~lL~ss~------d~eVr~~AL~aLsnLas~~~~~~~Lve  369 (747)
                      ....+                         ...++++.++.++. ..      +..++..++.+|.+++........+.+
T Consensus       130 ~~~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~i~~Lv~~l~-~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~l~~  208 (369)
T 6HB3_B          130 ILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFV-KGYDKKLTKYASFNYLAFFFADISRFKLGRMYFIE  208 (369)
T ss_pred             HHHHHHhcCCCCCCHHHHHHHHHHHHHHHHHHCCcHHHHHHHhc-CCCCccCCCHHHHHHHHHHHHHHcCCHHHHHHHHH
Confidence            11212                         11345666666665 32      345666777777777765444444444


No 126
>3OPB_A SWI5-dependent HO expression protein 4; HEAT and ARM fold, Myosin; 2.9A {Saccharomyces cerevisiae}
Probab=97.06  E-value=7.2e-07  Score=100.91  Aligned_cols=156  Identities=12%  Similarity=0.164  Sum_probs=96.5  Template_Neff=10.500

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKE------KGLPQIARLLQSGNSDVVRSGASLL  619 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~------giI~~Ll~LL~s~d~eVr~~AL~aL  619 (747)
                      .++++.|+.++. +.+..++..++.+|.+++.....     ....+.+.      ++++.|+.++.+.++.++..++++|
T Consensus       605 ~~~~~~L~~ll~-~~~~~v~~~a~~~L~~L~~~~~~-----~~~~~~~~~~~~~~~~l~~L~~ll~~~~~~v~~~a~~~L  678 (778)
T 3OPB_A          605 KVYWSTIENLML-DENVPLQRSTLELISNMMSHPLT-----IAAKFFNLENPQSLRNFNILVKLLQLSDVESQRAVAAIF  678 (778)
T ss_dssp             HHHHHHHHHGGG-CSSHHHHHHHHHHHHHHHTSGGG-----TGGGTSCCSSHHHHHHHHHHHHGGGCSCHHHHHHHHHHH
T ss_pred             ccHHHHHHHHhh-CCCHHHHHHHHHHHHHHhcChhH-----HHHHhcCCCChhHHHhHHHHHHHhcCCCHHHHHHHHHHH
Confidence            356777777776 35677788888888888864321     12222332      6778888888777778888888888


Q NP_000290.2     620 SNMSRH-PLL-HRVMG-NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----K-QYFS-SSMLNNIIN  690 (747)
Q Consensus       620 snLa~~-~e~-~~ll~-~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~-~Lve-~giL~~Ll~  690 (747)
                      ++++.. +.. ...+. .++++.|+.++.+..    .+..++..++++|.+++...+...    . .+.+ .++++.|..
T Consensus       679 ~~l~~~~~~~~~~l~~~~~~i~~L~~~L~~~~----~~~~l~~~a~~aL~~L~~~~~~~~~~~~~~~l~~~~~~~~~L~~  754 (778)
T 3OPB_A          679 ANIATTIPLIAKELLTKKELIENAIQVFADQI----DDIELRQRLLMLFFGLFEVIPDNGTNEVYPLLQENQKLKDALNM  754 (778)
T ss_dssp             HHHHHHCHHHHHHHTTCHHHHHHHHHHHHHTT----TCHHHHHHHHHHHHHHHTTCCSTTTTSCCHHHHSCHHHHHHHHH
T ss_pred             HHHHccCHHHHHHHhcCccHHHHHHHHHHhCC----CCHHHHHHHHHHHHHHHhhCCcCCCccchhHHhcCHHHHHHHHH
Confidence            888755 222 23332 567777777776510    145678888888888886533222    0 1222 256777777


Q NP_000290.2     691 LCRSSA-SPKAAEAARLLLSDM  711 (747)
Q Consensus       691 LL~s~~-d~eVr~aAL~aLsnL  711 (747)
                      ++.... ++.++..+..+|.++
T Consensus       755 ~l~~~~~~~~~~~~~~~~L~~l  776 (778)
T 3OPB_A          755 SLKRGDSGPEFSAAIPVILAKI  776 (778)
T ss_dssp             HHSSSSSCSSTTSHHHHHHTTC
T ss_pred             HHhhCCCCHHHHHHHHHHHHhc
Confidence            776431 335555566555543


No 127
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=97.02  E-value=7.7e-07  Score=80.85  Aligned_cols=113  Identities=29%  Similarity=0.332  Sum_probs=76.4  Template_Neff=13.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++.........+.
T Consensus         4 ~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~   83 (252)
T 4HXT_A            4 VEKLVKLLTSTDSETQKEAARDLAEIASGPASAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIV   83 (252)
T ss_dssp             HHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHH
T ss_pred             HHHHHHHcCCCCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
Confidence            44556666667778888999999988765433333334446677777777777778888999999988765433333333


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ..++++.+...+. ..++.++..++.++.+++..
T Consensus        84 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  116 (252)
T 4HXT_A           84 DAGGVEVLVKLLT-STDSEVQKEAARALANIASG  116 (252)
T ss_dssp             HTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTS
T ss_pred             HCChHHHHHHHcc-CCCHHHHHHHHHHHHHHHcC
Confidence            3456667777775 45567777777887777653


No 128
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=97.01  E-value=9.1e-07  Score=98.43  Aligned_cols=136  Identities=15%  Similarity=0.144  Sum_probs=91.1  Template_Neff=10.100

Q NP_000290.2     245 LTIPKAVQYLSS--QDEKYQAIGAYYIQHTCFQDES-----------------AKQQVY-QLGGICKLVDLLRSPNQNVQ  304 (747)
Q Consensus       245 ~iL~~Ll~lL~s--sd~eVr~sAL~aLsnLs~~~~~-----------------~~~~li-~~~IL~~Ll~lL~s~d~eVr  304 (747)
                      .+++.|+..+..  .+..+...++.+|..++.....                 ....+. ..+.++.++.++...+..++
T Consensus        60 ~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~~~~~~~  139 (651)
T 3GQ2_A           60 QAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVR  139 (651)
T ss_dssp             HHHHHHHHHHTTCTTCHHHHHHHHHHHHHHHCCSSSCC----------CHHHHHHHHHHTSHHHHHTHHHHTTCCCHHHH
T ss_pred             cHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCChHhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccCCCHHHH
Confidence            456667777764  4567788888888888764332                 112222 35667777777777777888


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKL-ETR-RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~-~ll-~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.+|..++........ .+. ..+.+..++.++. ..+..++..++.+|.+++.. ......+.. ++++.|+.++.
T Consensus       140 ~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~-~~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~g~~~~L~~ll~  218 (651)
T 3GQ2_A          140 WPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLA-DSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIIT  218 (651)
T ss_dssp             HHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHGGGGG-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCChHHHHHHHHH
Confidence            9999999988865432211 222 3456778888886 55677888999999999873 333333333 88888888886


Q NP_000290.2     381 I  381 (747)
Q Consensus       381 ~  381 (747)
                      .
T Consensus       219 ~  219 (651)
T 3GQ2_A          219 E  219 (651)
T ss_dssp             H
T ss_pred             H
Confidence            4


No 129
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=97.01  E-value=9.1e-07  Score=98.43  Aligned_cols=136  Identities=15%  Similarity=0.144  Sum_probs=90.5  Template_Neff=10.100

Q NP_000290.2     245 LTIPKAVQYLSS--QDEKYQAIGAYYIQHTCFQDES-----------------AKQQVY-QLGGICKLVDLLRSPNQNVQ  304 (747)
Q Consensus       245 ~iL~~Ll~lL~s--sd~eVr~sAL~aLsnLs~~~~~-----------------~~~~li-~~~IL~~Ll~lL~s~d~eVr  304 (747)
                      .+++.|+..+..  .+..+...++.+|..++.....                 ....+. ..+.++.++.++...+..++
T Consensus        60 ~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~~~~~~~  139 (651)
T 3GRL_A           60 QAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVR  139 (651)
T ss_dssp             CCHHHHHHHHHSCTTCHHHHHHHHHHHHHHHCCC--------------CHHHHHHHHHHHSTHHHHHHHHHTTCCCHHHH
T ss_pred             cHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCChHhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccCCCHHHH
Confidence            456667777764  4567788888888888764332                 112222 35667777777777777888


Q NP_000290.2     305 QAAAGALRNLVFRSTTNKL-ETR-RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       305 ~~AL~aLs~La~~~~~~~~-~ll-~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ..++.+|..++........ .+. ..+.+..++.++. ..+..++..++.+|.+++.. ......+.. ++++.|+.++.
T Consensus       140 ~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~-~~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~g~~~~L~~ll~  218 (651)
T 3GRL_A          140 WPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLA-DSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIIT  218 (651)
T ss_dssp             HHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGG-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCChHHHHHHHHH
Confidence            9999999988865432211 222 3456778888886 55677888999999999873 333333333 88888888886


Q NP_000290.2     381 I  381 (747)
Q Consensus       381 ~  381 (747)
                      .
T Consensus       219 ~  219 (651)
T 3GRL_A          219 E  219 (651)
T ss_dssp             H
T ss_pred             H
Confidence            4


No 130
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=97.01  E-value=8.1e-07  Score=80.69  Aligned_cols=114  Identities=27%  Similarity=0.320  Sum_probs=76.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        45 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  124 (252)
T 4HXT_A           45 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAI  124 (252)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCChHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677888889999998876544333333444667777777777777888889999988876443332233


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       125 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  158 (252)
T 4HXT_A          125 VDAGGVEVLVKLLT-STDSEVQKEAARALANIASG  158 (252)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHCCHHHHHHHHhh-CCCHHHHHHHHHHHHHHHcC
Confidence            33356666666665 45567777788888877764


No 131
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=97.00  E-value=8.3e-07  Score=82.05  Aligned_cols=114  Identities=25%  Similarity=0.284  Sum_probs=75.7  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.++.++..++.++..++.........+
T Consensus        44 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  123 (281)
T 4PLS_B           44 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  123 (281)
T ss_dssp             HHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCCcHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666666777888889999998876443333333444577777777777777888888898888876433332333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       124 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  157 (281)
T 4PLS_B          124 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASG  157 (281)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcC
Confidence            33456666777665 44566777777777776653


No 132
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=96.99  E-value=9.5e-07  Score=87.41  Aligned_cols=114  Identities=22%  Similarity=0.254  Sum_probs=75.1  Template_Neff=12.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+..++.+.++.++..++.++.+++.. .......+...++++.+..++.. .+..++..++.+|.+++.......
T Consensus       127 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  206 (354)
T 5IZA_A          127 GCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENK  206 (354)
T ss_dssp             HHHHHHHHGGGCSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTTCHHHH
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChHhH
Confidence            3455666677766778888999999998874 22223334445677778888776 677888889999999886533333


Q NP_000290.2     323 LETRR-QNGIREAVSLLRR---TGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       323 ~~ll~-~~IL~~Ll~lL~s---s~d~eVr~~AL~aLsnLa  358 (747)
                      ..+.. .++++.+..++..   ..+..++..++.++..+.
T Consensus       207 ~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~L~~l~  246 (354)
T 5IZA_A          207 ADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVS  246 (354)
T ss_dssp             HHHHTSTTHHHHHHHHTCSSCSSCCHHHHHHHHHHHHHHH
T ss_pred             HHHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHHHHHHHH
Confidence            33444 4667777777651   112456666777777765


No 133
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=96.97  E-value=1e-06  Score=87.19  Aligned_cols=113  Identities=22%  Similarity=0.270  Sum_probs=74.6  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      +++.+..++.+.++.++..++.++.+++.. .......+...++++.+..++.. .+..++..++.+|.+++........
T Consensus       128 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~  207 (354)
T 5IZ8_A          128 CMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKA  207 (354)
T ss_dssp             HHHHHHHGGGSSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHHTSCHHHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChHhHH
Confidence            455666677666778888999999998874 22223334445677778888776 6778888899999998865333333


Q NP_000290.2     324 ETRR-QNGIREAVSLLRR---TGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       324 ~ll~-~~IL~~Ll~lL~s---s~d~eVr~~AL~aLsnLa  358 (747)
                      .+.. .++++.+..++..   ..+..++..++.++..+.
T Consensus       208 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~L~~l~  246 (354)
T 5IZ8_A          208 DICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVS  246 (354)
T ss_dssp             HHHTSTTHHHHHHHHTTCCCTTSCCHHHHHHHHHHHHHH
T ss_pred             HHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHHHHHHHH
Confidence            3444 4667777777651   112456666777777765


No 134
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=96.96  E-value=1.1e-06  Score=90.60  Aligned_cols=135  Identities=25%  Similarity=0.264  Sum_probs=91.1  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.+|.+++.........+...++++.+..++...++.++..++.+|..++.........+
T Consensus       342 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  421 (510)
T 6SA7_B          342 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  421 (510)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            34445555556667788888888888876544433334445677788888877778888899999998875544433344


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVII  381 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~~  381 (747)
                      ...++++.+..++. ..++.++..++.++..++.... ....+.. ++++.|..++..
T Consensus       422 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  478 (510)
T 6SA7_B          422 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQSH  478 (510)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGGC
T ss_pred             HHcCcHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCchHHHHHHHCCHHHHHHHHhhc
Confidence            44567778888886 5677889999999999985432 2222333 667777776653


No 135
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=96.95  E-value=1.1e-06  Score=80.29  Aligned_cols=135  Identities=24%  Similarity=0.251  Sum_probs=89.9  Template_Neff=12.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++.........
T Consensus        92 ~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  171 (247)
T 4V3Q_A           92 GALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQA  171 (247)
T ss_dssp             THHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            34556666666667788888899998887654433333344567777888777777788888999998887654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+...+. ..++.++..++.++..++.... ....+.. ++++.|..++.
T Consensus       172 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  228 (247)
T 4V3Q_A          172 VIDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQS  228 (247)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCHHHHHHHHHh
Confidence            334456777777776 5567788889999998886532 2222333 66677776665


No 136
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=96.93  E-value=1.2e-06  Score=84.95  Aligned_cols=134  Identities=21%  Similarity=0.263  Sum_probs=83.9  Template_Neff=12.500

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      .+++.+...+.+.++.++..++.++.+++.. .......+...++++.+..++.. .++.++..++.++.+++.......
T Consensus       122 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~  201 (339)
T 5Z8H_A          122 GCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENK  201 (339)
T ss_pred             ChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCCHHHHHHHHHCCcHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHH
Confidence            3455666667666778888999999998874 22223334445677778887776 577788889999999886444333


Q NP_000290.2     323 LETRR-QNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSS----TDELKEELIA-DALPVLADRV  379 (747)
Q Consensus       323 ~~ll~-~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas----~~~~~~~Lve-giLe~Lv~LL  379 (747)
                      ..+.. .++++.+..++. ..+    ..++..++.++.++..    .......+.. ++++.++.++
T Consensus       202 ~~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l  267 (339)
T 5Z8H_A          202 ADICAVDGALAFLVGTLT-YRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHL  267 (339)
T ss_pred             HHHHHhcChHHHHHHHhc-CCCCCCCHHHHHHHHHHHHHHHHhhccCHHHHHHHHHCCHHHHHHHHH
Confidence            34444 466777777775 222    5667777777777752    2222222222 5555555555


No 137
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=96.89  E-value=1.4e-06  Score=80.58  Aligned_cols=112  Identities=27%  Similarity=0.322  Sum_probs=75.3  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       173 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  252 (286)
T 5AEI_B          173 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  252 (286)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHccCCCHHHHHHHHHHHHHHhCCCHHHHHHH
Confidence            45556666666677788888999988876544333333344567777777777777888889999988885544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+...+. ..++.++..++.++..++
T Consensus       253 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  284 (286)
T 5AEI_B          253 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ  284 (286)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHH
T ss_pred             HHcCHHHHHHHHhh-CCCHHHHHHHHHHHHHHh
Confidence            34456677777776 456677777877777664


No 138
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=96.88  E-value=1.5e-06  Score=85.84  Aligned_cols=124  Identities=24%  Similarity=0.343  Sum_probs=84.2  Template_Neff=12.000

Q NP_000290.2     258 DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLETRRQNGIREAV  335 (747)
Q Consensus       258 d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~ll~~~IL~~Ll  335 (747)
                      +..++..++.++.+++.........+.. .++++.+..++...++.++..++.++.+++.. .......+...++++.+.
T Consensus        97 ~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  176 (354)
T 5IZA_A           97 SITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALM  176 (354)
T ss_dssp             HHHHHHHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGGCSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHH
T ss_pred             CHHHHHHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHH
Confidence            5677888888888887644333333333 46777888888777788889999999998864 222233344456777788


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      .++....++.++..++.++.+++.. ......+..  ++++.|+.++..
T Consensus       177 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~  225 (354)
T 5IZA_A          177 ECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTY  225 (354)
T ss_dssp             HHHHHCCCHHHHHHHHHHHHHHHTTCHHHHHHHHTSTTHHHHHHHHTCS
T ss_pred             HHHHhcCCHHHHHHHHHHHHHHHcCChHhHHHHHhhccHHHHHHHHHhh
Confidence            8876225677888899999999876 444434433  667777777664


No 139
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=96.88  E-value=1.6e-06  Score=85.78  Aligned_cols=124  Identities=24%  Similarity=0.343  Sum_probs=84.2  Template_Neff=12.000

Q NP_000290.2     258 DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRNLVFR-STTNKLETRRQNGIREAV  335 (747)
Q Consensus       258 d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~-~~~~~~~ll~~~IL~~Ll  335 (747)
                      +..++..++.++.+++.........+.. .++++.+..++...++.++..++.++.+++.. .......+...++++.+.
T Consensus        97 ~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  176 (354)
T 5IZ8_A           97 SITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRNLSWRADVNSKKTLREVGSVKALM  176 (354)
T ss_dssp             HHHHHHHHHHHHHHHHTTCHHHHHHHHHCHHHHHHHHHGGGSSCHHHHHHHHHHHHHHHTTCCHHHHHHHHHTTHHHHHH
T ss_pred             CHHHHHHHHHHHHHHhcCCHHHHHHHHccchHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCChhHHHHHHHCCHHHHHH
Confidence            5677888888888887644333333333 46777888888777788888999999998864 222233344456777788


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA--DALPVLADRVII  381 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve--giLe~Lv~LL~~  381 (747)
                      .++....++.++..++.+|.+++.. ......+..  ++++.|+.++..
T Consensus       177 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~  225 (354)
T 5IZ8_A          177 ECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTY  225 (354)
T ss_dssp             HHHHHCCSHHHHHHHHHHHHHHHTSCHHHHHHHHTSTTHHHHHHHHTTC
T ss_pred             HHHHhcCCHHHHHHHHHHHHHHHcCChHhHHHHHhhccHHHHHHHHHhh
Confidence            8876225677888899999999876 444333433  667777777664


No 140
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=96.87  E-value=1.6e-06  Score=88.90  Aligned_cols=135  Identities=18%  Similarity=0.233  Sum_probs=88.1  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLR----SPNQNVQQAAAGALRNLV---F  316 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~----s~d~eVr~~AL~aLs~La---~  316 (747)
                      +++.+..++. ..+..++..++.+|.+++...+.....+.. .++++.+..++.    ..+..++..++.++.+++   .
T Consensus       287 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~a~~~l~~l~~~~~  366 (458)
T 3NMZ_A          287 SVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIA  366 (458)
T ss_pred             HHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCchhHHHHHHhcChHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHHHHhc
Confidence            4555666665 456778888999999988743333333333 566777777765    224566777888887765   2


Q NP_000290.2     317 RSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS-TDELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       317 ~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas-~~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      ........+...++++.+..++. ..++.++..++.+|..++. .......+.. ++++.|..++..
T Consensus       367 ~~~~~~~~l~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~~~l~~~~~~~~L~~ll~~  432 (458)
T 3NMZ_A          367 TNEDHRQILRENNCLQTLLQHLK-SHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHS  432 (458)
T ss_pred             CCHHHHHHHHHCCcHHHHHHHhC-CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHHhC
Confidence            22223333344467777888886 5567889999999999987 3444444544 788888887754


No 141
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=96.87  E-value=1.6e-06  Score=89.20  Aligned_cols=134  Identities=26%  Similarity=0.306  Sum_probs=91.2  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.+|.+++.........+...++++.+...+.+.++.++..++.+|..++.........+
T Consensus       300 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  379 (510)
T 6SA7_B          300 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  379 (510)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHHHhCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHHHH
Confidence            45566666666677888889999998876544333344445677778888877778888899999999886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.+|..++.... ....+.. ++++.|+.++.
T Consensus       380 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  435 (510)
T 6SA7_B          380 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  435 (510)
T ss_dssp             HHTTHHHHHHHHHT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHhc
Confidence            44467777887776 5577888889999998865432 2223333 66777777664


No 142
>5TBK_C Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=96.87  E-value=1.7e-06  Score=90.04  Aligned_cols=367  Identities=17%  Similarity=0.192  Sum_probs=215.7  Template_Neff=12.200

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+... ++.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus       115 ~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  194 (521)
T 5TBK_C          115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  194 (521)
T ss_dssp             HHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHHHHHHTTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCHHHHHH
T ss_pred             cHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            445555555543 6678888888888887654333333334467777888887777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....+..++..++.++..++..........  .++++.+..++...                ++++
T Consensus       195 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v  258 (521)
T 5TBK_C          195 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHT----------------DVNI  258 (521)
T ss_dssp             HHHTTCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTCS----------------CHHH
T ss_pred             HHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHhhCC----------------CHHH
Confidence            33445677777777533344678888888888876533221111  15566666665431                2334


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-...      .+              ..++.+. -.+++..|...+..      .+..-...++..|.++
T Consensus       259 ~~~a~~~L~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l  311 (521)
T 5TBK_C          259 LVDTVWALSYLTDA------GN--------------EQIQMVI-DSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  311 (521)
T ss_dssp             HHHHHHHHHHHHHH------CH--------------HHHHHHH-HTTCHHHHGGGGGC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhcc------Ch--------------HHHHHHH-HCChHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            33343333221100      00              0000000 02333434333321      0111112222223332


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.|..++. +.++
T Consensus       312 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  340 (521)
T 5TBK_C          312 VTGT--------------------------------------------------DEQTQVVLNCDALSHFPALLT-HPKE  340 (521)
T ss_dssp             HTSC--------------------------------------------------HHHHHHHHHTTCGGGHHHHHT-CSCH
T ss_pred             HcCC--------------------------------------------------HHHHHHHHhCCHHHhHHHHhh-CCCH
Confidence            2110                                                  000112234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...++++.
T Consensus       341 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~  415 (521)
T 5TBK_C          341 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  415 (521)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHH
T ss_pred             HHHHHHHHHHHHHhCCCHH-----HHHHHHHCCcHHHHHHHHHhCCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHH
Confidence            8888999999999865332     223334557888888888887888999999999999864 2 11 22233467788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      |..++..      .++.++..++.+|.+++...+...    ..+.+.++++.|..++.+. ++.++..++.+|.+++...
T Consensus       416 L~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~L~~l~~~~  488 (521)
T 5TBK_C          416 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQFFSSD  488 (521)
T ss_dssp             HHGGGGS------SCHHHHHHHHHHHHHHHHHCSTTHHHHHHHHHHTTHHHHHHHHCSTT-CHHHHHHHHHHHHHHCCC-
T ss_pred             HHHHcCC------CCHHHHHHHHHHHHHHHHHhHHhHHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHHHHHHHHHhcCCC
Confidence            8888765      367888899999999887533211    2233446778888888766 7889999999999999766


Q NP_000290.2     716 ELQ  718 (747)
Q Consensus       716 ~~~  718 (747)
                      +..
T Consensus       489 ~~~  491 (521)
T 5TBK_C          489 DID  491 (521)
T ss_dssp             ---
T ss_pred             CCC
Confidence            543


No 143
>5TBK_D Importin subunit alpha-3, Regulator of; Nuclear Import, Importin alpha, RCC1; 3.45A {Homo sapiens}
Probab=96.87  E-value=1.7e-06  Score=90.04  Aligned_cols=367  Identities=17%  Similarity=0.192  Sum_probs=215.0  Template_Neff=12.200

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+... ++.++..++.++..++.........+...++++.+..++.+.++.++..++.++..++.........
T Consensus       115 ~i~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  194 (521)
T 5TBK_D          115 ILPILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQNVCEQAVWALGNIIGDGPQCRDY  194 (521)
T ss_dssp             HHHHHHHHHHCCSCHHHHHHHHHHHHHHHTSCHHHHHHHHTTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCHHHHHH
T ss_pred             cHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            445555555543 6678888888888887654333333334467777888887777888999999999888654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELI--ADALPVLADRVIIPFSGWCDGNSNMSREVVDPEV  402 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lv--egiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~  402 (747)
                      +...+++..+...+....+..++..++.++..++..........  .++++.+..++...                ++++
T Consensus       195 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~----------------~~~v  258 (521)
T 5TBK_D          195 VISLGVVKPLLSFISPSIPITFLRNVTWVMVNLCRHKDPPPPMETIQEILPALCVLIHHT----------------DVNI  258 (521)
T ss_dssp             HHHTCCHHHHHTTCCTTSCHHHHHHHHHHHHHHHCCCSSCCCHHHHHHHHHHHHHHTTCS----------------CHHH
T ss_pred             HHHCCcHHHHHHHhCCCCCHHHHHHHHHHHHHHHcCCCCCCCHHHHHHHHHHHHHHhhCC----------------CHHH
Confidence            33445677777777533344678888888888876533221111  15566666665431                2334


Q NP_000290.2     403 FFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNL  482 (747)
Q Consensus       403 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  482 (747)
                      ...+..+|..-...      .+              ..++.+. -.+++..|...+..      .+..-...++..|.++
T Consensus       259 ~~~a~~~L~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~v~~~a~~~L~~l  311 (521)
T 5TBK_D          259 LVDTVWALSYLTDA------GN--------------EQIQMVI-DSGIVPHLVPLLSH------QEVKVQTAALRAVGNI  311 (521)
T ss_dssp             HHHHHHHHHHHHHH------CH--------------HHHHHHH-HTTCHHHHGGGGGC------SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhcc------Ch--------------HHHHHHH-HCChHHHHHHHhcC------CCHHHHHHHHHHHHHH
Confidence            33343333221100      00              0000000 02333434333321      0111112222223332


Q NP_000290.2     483 SYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKD  562 (747)
Q Consensus       483 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~  562 (747)
                      ...-                                                  ......+.+.++++.|..++. +.++
T Consensus       312 ~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~~  340 (521)
T 5TBK_D          312 VTGT--------------------------------------------------DEQTQVVLNCDALSHFPALLT-HPKE  340 (521)
T ss_dssp             HTSC--------------------------------------------------HHHHHHHHHTTCGGGHHHHHH-CSCH
T ss_pred             HcCC--------------------------------------------------HHHHHHHHhCCHHHhHHHHhh-CCCH
Confidence            2110                                                  000112234467788888887 4677


Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P-LL-HRVMGNQVFPE  639 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~-e~-~~ll~~giI~~  639 (747)
                      .++..++.+|.+++...+.     ....+...++++.|..++.+.++.++..++.+|.+++.. . .. ..+...++++.
T Consensus       341 ~v~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~l~~~~~~~~  415 (521)
T 5TBK_D          341 KINKEAVWFLSNITAGNQQ-----QVQAVIDANLVPMIIHLLDKGDFGTQKEAAWAISNLTISGRKDQVAYLIQQNVIPP  415 (521)
T ss_dssp             HHHHHHHHHHHHHTTSCHH-----HHHHHHTTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHHHHTTTCHHH
T ss_pred             HHHHHHHHHHHHHhCCCHH-----HHHHHHHCCcHHHHHHHHHhCCHHHHHHHHHHHHHHHccCCHHHHHHHHHCCCHHH
Confidence            8888999999999865332     223334557888888888887888999999999999864 2 11 22233467788


Q NP_000290.2     640 VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA----KQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       640 Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~----~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      |..++..      .++.++..++.+|.+++...+...    ..+.+.++++.|..++.+. ++.++..++.+|.+++...
T Consensus       416 L~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~l~~~~~~~~l~~ll~~~-~~~v~~~a~~~L~~l~~~~  488 (521)
T 5TBK_D          416 FCNLLTV------KDAQVVQVVLDGLSNILKMAEDEAETIGNLIEECGGLEKIEQLQNHE-NEDIYKLAYEIIDQFFSSD  488 (521)
T ss_dssp             HHGGGGS------SCHHHHHHHHHHHHHHHHHCSTTHHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHHHHHHHHHHCC--
T ss_pred             HHHHcCC------CCHHHHHHHHHHHHHHHHHhHHhHHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHHHHHHHHHhcCCC
Confidence            8888765      367888899999999887533211    2233446778888888766 7889999999999999766


Q NP_000290.2     716 ELQ  718 (747)
Q Consensus       716 ~~~  718 (747)
                      +..
T Consensus       489 ~~~  491 (521)
T 5TBK_D          489 DID  491 (521)
T ss_dssp             ---
T ss_pred             CCC
Confidence            543


No 144
>6HB1_A Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 2.33A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.86  E-value=1.8e-06  Score=89.00  Aligned_cols=169  Identities=9%  Similarity=0.050  Sum_probs=120.8  Template_Neff=10.100

Q NP_000290.2     547 DAIRTYLNLMGK--SKKDATLEACAGALQNLTASKGLMSSGMSQLIGL--KEKGLPQIARLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       547 G~I~~LL~LL~s--s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~lli--e~giI~~Ll~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      ++++.|+.++..  +.++.++..++++|.+++....      ....+.  +.++++.|+.++.+.+..++..++++|.++
T Consensus        51 ~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~------~~~~l~~~~~g~i~~L~~ll~~~~~~~~~~a~~~L~nl  124 (369)
T 6HB1_A           51 RPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL------VRNIILSDDKKFLKFLVWKIVDLTNPNADIMCILLSNL  124 (369)
T ss_dssp             HHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH------HHHCCCCCSTHHHHHHHHHHHCTTCTTHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH------HHHHHhhcChHHHHHHHHHHHcCCCccHHHHHHHHHHH
Confidence            588999999952  1356788899999999986532      244445  689999999999887778889999999999


Q NP_000290.2     623 SRHPLLH-RV-------------------------MGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA  676 (747)
Q Consensus       623 a~~~e~~-~l-------------------------l~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~  676 (747)
                      +...... .+                         ...++++.|+.++.........++.++..++++|.+|+.. +..+
T Consensus       125 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~i~~Lv~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~-~~~~  203 (369)
T 6HB1_A          125 AKDDGILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKGYDKKLTKYASFNYLAFFFADISRF-KLGR  203 (369)
T ss_dssp             TTSGGGGGGGGCBCSCSSSEEETTEEECCCCTTTCCCSBHHHHHHHHHHHCGGGSSCSSCCCTTHHHHHHHHTTS-HHHH
T ss_pred             ccChhHHHHHhhcCCCCCCchhhhHHHHHHcHHHHHHhhHHHHHHHHHhhcCcccCCchhchHHHHHHHHHHcCC-HHHH
Confidence            9864332 22                         1246778888887652000000456788899999999875 5666


Q NP_000290.2     677 KQYFSSS------MLNNIINLCR-SSASPKAAEAARLLLSDMWSSKELQGVLRQ  723 (747)
Q Consensus       677 ~~Lve~g------iL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~  723 (747)
                      ..+.+.+      .+..++.++. +. +..++..++.+|.+++.+.+....+..
T Consensus       204 ~~l~~~g~~~~~~~l~~ll~~l~~~~-~~~~~~~a~~~L~nl~~~~~~~~~i~~  256 (369)
T 6HB1_A          204 MYFIEEQEYDGVVPISKLLVFTEKYD-AKVRREGVASTIKNSLFDSETHERLLK  256 (369)
T ss_dssp             HHHHSCCTTTCCCGGGGTGGGGGCTT-CHHHHHHHHHHHHHHTCCGGGHHHHHH
T ss_pred             HHHhhcccccCcccHHHHHHHhcccC-CHHHHHHHHHHHHHHhcCHHHHHHHhc
Confidence            6677766      4666666665 34 678899999999999988775544443


No 145
>6HB2_D Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; HET: MSE; 2.7A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.86  E-value=1.8e-06  Score=89.00  Aligned_cols=169  Identities=9%  Similarity=0.050  Sum_probs=120.8  Template_Neff=10.100

Q NP_000290.2     547 DAIRTYLNLMGK--SKKDATLEACAGALQNLTASKGLMSSGMSQLIGL--KEKGLPQIARLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       547 G~I~~LL~LL~s--s~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~lli--e~giI~~Ll~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      ++++.|+.++..  +.++.++..++++|.+++....      ....+.  +.++++.|+.++.+.+..++..++++|.++
T Consensus        51 ~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~------~~~~l~~~~~g~i~~L~~ll~~~~~~~~~~a~~~L~nl  124 (369)
T 6HB2_D           51 RPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL------VRNIILSDDKKFLKFLVWKIVDLTNPNADIMCILLSNL  124 (369)
T ss_dssp             HHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH------HHHCCCCCCTHHHHHHHHHHSCTTCTTHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH------HHHHHhhcChHHHHHHHHHHHcCCCccHHHHHHHHHHH
Confidence            588999999952  1356788899999999986532      244445  689999999999887778889999999999


Q NP_000290.2     623 SRHPLLH-RV-------------------------MGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA  676 (747)
Q Consensus       623 a~~~e~~-~l-------------------------l~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~  676 (747)
                      +...... .+                         ...++++.|+.++.........++.++..++++|.+|+.. +..+
T Consensus       125 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~i~~Lv~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~-~~~~  203 (369)
T 6HB2_D          125 AKDDGILAVLNIKRNSSGEEVDDGLKLAALNKEVFKSLRAMDCLMDCFVKGYDKKLTKYASFNYLAFFFADISRF-KLGR  203 (369)
T ss_dssp             TTSGGGGGGGGCBCSCSSSEEETTEEECCCCTTTCCCSBHHHHHHHHHHHHGGGSSCSSCCCTTHHHHHHHHTTS-HHHH
T ss_pred             ccChhHHHHHhhcCCCCCCchhhhHHHHHHcHHHHHHhhHHHHHHHHHhhcCcccCCchhchHHHHHHHHHHcCC-HHHH
Confidence            9864332 22                         1246778888887652000000456788899999999875 5666


Q NP_000290.2     677 KQYFSSS------MLNNIINLCR-SSASPKAAEAARLLLSDMWSSKELQGVLRQ  723 (747)
Q Consensus       677 ~~Lve~g------iL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~~~~~~~~~  723 (747)
                      ..+.+.+      .+..++.++. +. +..++..++.+|.+++.+.+....+..
T Consensus       204 ~~l~~~g~~~~~~~l~~ll~~l~~~~-~~~~~~~a~~~L~nl~~~~~~~~~i~~  256 (369)
T 6HB2_D          204 MYFIEEQEYDGVVPISKLLVFTEKYD-AKVRREGVASTIKNSLFDSETHERLLK  256 (369)
T ss_dssp             HHHHSCCTTTCSCTHHHHGGGGGCTT-CHHHHHHHHHHHHHHTCSGGGHHHHHH
T ss_pred             HHHhhcccccCcccHHHHHHHhcccC-CHHHHHHHHHHHHHHhcCHHHHHHHhc
Confidence            6677766      4666666665 34 678899999999999988775544443


No 146
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=96.84  E-value=1.8e-06  Score=81.45  Aligned_cols=114  Identities=25%  Similarity=0.284  Sum_probs=77.1  Template_Neff=13.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..+..........+
T Consensus        47 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  126 (328)
T 5MFD_C           47 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  126 (328)
T ss_dssp             CHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHHhhcCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666777777888899999988876543333333344567777777777777888889999988876533333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..+...
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  160 (328)
T 5MFD_C          127 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASG  160 (328)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            33456667777775 45667777788888777653


No 147
>6SA7_B DARPin-Armadillo fusion C8long83; protein fusion, DARPin, Armadillo, shared; 3.3A {synthetic construct}
Probab=96.84  E-value=1.8e-06  Score=88.77  Aligned_cols=115  Identities=27%  Similarity=0.318  Sum_probs=78.7  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.+|..++.........+...++++.+..++.+.++.++..++.++..++.........+
T Consensus       384 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  463 (510)
T 6SA7_B          384 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  463 (510)
T ss_dssp             HHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCchHHHHH
Confidence            34445555555667778888888888865544433344445677888888887788889999999999985544433333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD  361 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~  361 (747)
                      ...++++.+..++. +.++.++..++.++..+....
T Consensus       464 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~  498 (510)
T 6SA7_B          464 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLGSGG  498 (510)
T ss_dssp             HHTTHHHHHHHGGG-CSSHHHHHHHHHHHHHHTC--
T ss_pred             HHCCHHHHHHHHhh-ccchHHHHHHHHHHHHHhhcc
Confidence            34456777777776 556788888999888887643


No 148
>6S9O_F designed Armadillo repeat protein with; peptide binder, repeat protein, designed; HET: CA, EDO; 3.17A {synthetic construct}
Probab=96.77  E-value=2.5e-06  Score=81.50  Aligned_cols=115  Identities=28%  Similarity=0.317  Sum_probs=77.6  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        46 ~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  125 (344)
T 6S9O_F           46 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALRNIASGGNEQIQA  125 (344)
T ss_dssp             TCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHSCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             ChHHHHHHHcCCCCHHHHHHHHHHHHHHhcCChhHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCchHHHH
Confidence            34556666677777788889999999887654333333334456777777777777788888999998887643333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      +...++++.+...+. ..++.++..++.++..++..
T Consensus       126 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  160 (344)
T 6S9O_F          126 VIDAGALPALVQLLS-SPNEQILSSALGALSNIASG  160 (344)
T ss_dssp             HHHTTCHHHHHHHTT-CSCHHHHHHHHHHHHHHHTS
T ss_pred             HHhCCHHHHHHHHhc-CCcHHHHHHHHHHHHHHHcC
Confidence            333456677777775 45667777888888877653


No 149
>1XM9_A plakophilin 1  Plakophilin-1; armadillo repeat, CELL ADHESION; 2.8A {Homo sapiens} SCOP: a.118.1.24
Probab=96.77  E-value=2.5e-06  Score=86.12  Aligned_cols=167  Identities=15%  Similarity=0.182  Sum_probs=108.5  Template_Neff=12.600

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL----------------QS  606 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL----------------~s  606 (747)
                      +++.++++.|+.++....++.++..++.+|.+++....      ....+. .++++.|+.++                ..
T Consensus        82 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~------~~~~~~-~~~~~~l~~~l~~~~~~~~~~~~~~~~~~  154 (457)
T 1XM9_A           82 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE------LKEELI-ADALPVLADRVIIPFSGWCDGNSNMSREV  154 (457)
T ss_dssp             HHHTTCHHHHHHHHTTCCCHHHHHHHHHHHHHHHTSSS------THHHHH-HHHHHHCCCCCCHHHHTCC---------C
T ss_pred             HHhcChHHHHHHHhhhCCCHHHHHHHHHHHHHHhCCHH------HHHHHH-cchHHHHHHHhccccCCCCCCCCCccccc
Confidence            45677888888888633566788889999999987422      123333 57888888888                56


Q NP_000290.2     607 GNSDVVRSGASLLSNMSRHPLL-HRVMG-NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-----------  673 (747)
Q Consensus       607 ~d~eVr~~AL~aLsnLa~~~e~-~~ll~-~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-----------  673 (747)
                      .++.++..++++|.+++..... ..+.. .++++.++.++.........+..++..++.+|.+++...+           
T Consensus       155 ~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~  234 (457)
T 1XM9_A          155 VDPEVFFNATGCLRNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLE  234 (457)
T ss_dssp             CCHHHHHHHHHHHHHHTTSHHHHHHHTTSTTHHHHHHHHHHHHHHHTCTTCTTHHHHHHHHHHHTTTHHHHSCCHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHccChHHHHHHHhcccHHHHHHHHHHHhhhcCcCCHHHHHHHHHHHHHHhcccccCCCcchhhhh
Confidence            6788899999999999976433 22332 3567777777764100000256788889999999886311           


Q NP_000290.2     674 ---------------------------------------QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       674 ---------------------------------------e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                                                             .....+...++++.++.++....+..++..++.+|.+++..
T Consensus       235 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~  314 (457)
T 1XM9_A          235 YNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTAS  314 (457)
T ss_dssp             HTC----------------------------CCCCCSSCCGGGGGGSHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTC
T ss_pred             hcccccccccccccccCcccchhccccccCCCCcccCCCchhHHhhchhHHHHHHHHhccCCCHHHHHHHHHHHHHHHhc
Confidence                                                   11122334456667777766532556677788888887765


Q NP_000290.2     715 KE  716 (747)
Q Consensus       715 ~~  716 (747)
                      .+
T Consensus       315 ~~  316 (457)
T 1XM9_A          315 KG  316 (457)
T ss_dssp             SS
T ss_pred             cc
Confidence            54


No 150
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=96.77  E-value=2.5e-06  Score=77.32  Aligned_cols=114  Identities=27%  Similarity=0.311  Sum_probs=76.9  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       129 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  208 (252)
T 4HXT_A          129 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPTSAIKAI  208 (252)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSBHHHHHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            34555555666667788888888888876543333333344567777777777777888889999988886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++.+++..
T Consensus       209 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~  242 (252)
T 4HXT_A          209 VDAGGVEVLQKLLT-STDSEVQKEAQRALENIKSG  242 (252)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHHHT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcC
Confidence            33356777777776 45677888888888888764


No 151
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=96.73  E-value=3e-06  Score=84.23  Aligned_cols=132  Identities=23%  Similarity=0.240  Sum_probs=87.4  Template_Neff=12.400

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRR  327 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~  327 (747)
                      ..++..+.+.+..++..++.++.+++.........+...++++.+..++.+.++.++..++.++.+++.........+..
T Consensus       160 ~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~  239 (397)
T 6SA6_A          160 AALVLKLNANDDQIIQEALWKLGNHASGGNLRIQWVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVID  239 (397)
T ss_dssp             HHHHHHTTCSCHHHHHHHHHHHHHHHTTTHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHH
T ss_pred             HHHHHHccCCCHHHHHHHHHHHHHHhhCCchHHHHHHHCCcHHHHHHHcCCCCHHHHHHHHHHHHHHhCCCHHHHHHHHH
Confidence            34445555567788889999999988755444444445567788888888777788889999999988654443334444


Q NP_000290.2     328 QNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       328 ~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .++++.+..++. ..++.++..++.++.+++..... ...+.. ++++.|+.+|.
T Consensus       240 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  293 (397)
T 6SA6_A          240 AGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLS  293 (397)
T ss_dssp             TTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             CCcHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCcHHHHHHHHhCChHHHHHHHhc
Confidence            567777888876 55677888888888888654222 222222 45555555543


No 152
>3NMZ_A APC variant protein, Rho guanine; protein-protein complex, armadillo repeats, CELL; 3.01A {Homo sapiens}
Probab=96.71  E-value=3.3e-06  Score=86.51  Aligned_cols=135  Identities=22%  Similarity=0.327  Sum_probs=88.0  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLSSQ-----------DEKYQAIGAYYIQHTCFQDESAKQQVYQ-LGGICKLVDLLRSPNQNVQQAAAGALRN  313 (747)
Q Consensus       246 iL~~Ll~lL~ss-----------d~eVr~sAL~aLsnLs~~~~~~~~~li~-~~IL~~Ll~lL~s~d~eVr~~AL~aLs~  313 (747)
                      +++.+..++...           +..++..++.+|.+++.........+.. .++++.+..++...+..++..++.++.+
T Consensus       190 ~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~  269 (458)
T 3NMZ_A          190 GLQAIAELLQVDCEMYGLTNDHYSITLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQQVIASVLRN  269 (458)
T ss_pred             hHHHHHHHHhccccCCCCCCCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHhCCcHHHHHHHhcCCCHHHHHHHHHHHHH
Confidence            445555555543           5678888999999988754433332333 4677888888877778889999999999


Q NP_000290.2     314 LVFRST-TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELI--ADALPVLADRVI  380 (747)
Q Consensus       314 La~~~~-~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lv--egiLe~Lv~LL~  380 (747)
                      ++.... .....+...++++.+..++....+..++..++.++.+++.. ......+.  .++++.|+.++.
T Consensus       270 l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  340 (458)
T 3NMZ_A          270 LSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTENKADICAVDGALAFLVGTLT  340 (458)
T ss_pred             HHCCCChhHHHHHHHCCHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCchhHHHHHHhcChHHHHHHHHc
Confidence            886543 22333444457777777775234567888889999998873 33333333  256666666654


No 153
>6HB1_A Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 2.33A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.61  E-value=5.3e-06  Score=85.37  Aligned_cols=93  Identities=22%  Similarity=0.297  Sum_probs=66.7  Template_Neff=10.100

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ--NGIREAVSLLRR--TGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~--~IL~~Ll~lL~s--s~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +.++.++.++...++.++..++.++.++.....  ...+...  +.++.|+.++..  ..++.++..++.+|.+++....
T Consensus         9 ~~i~~lv~lL~~~~~~v~~~a~~~L~~l~~~~~--~~~l~~~~~~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~   86 (369)
T 6HB1_A            9 SQLNELVEFLHSPQPAVRQIAIDNLVGFSAGPT--SKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL   86 (369)
T ss_dssp             CCHHHHHHGGGCSCHHHHHHHHHHHGGGGSSGG--GGGGGHHHHHHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH
T ss_pred             hhHHHHHHHhcCCCHHHHHHHHHHHhHhcCCCC--chhhhcCCchHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH
Confidence            456677777777777888899999988876543  2333333  478888888852  1356788899999999987655


Q NP_000290.2     363 LKEELI--A-DALPVLADRVII  381 (747)
Q Consensus       363 ~~~~Lv--e-giLe~Lv~LL~~  381 (747)
                      ....+.  + ++++.|+.++..
T Consensus        87 ~~~~l~~~~~g~i~~L~~ll~~  108 (369)
T 6HB1_A           87 VRNIILSDDKKFLKFLVWKIVD  108 (369)
T ss_dssp             HHHCCCCCSTHHHHHHHHHHHC
T ss_pred             HHHHHhhcChHHHHHHHHHHHc
Confidence            556666  5 888888888874


No 154
>6HB2_D Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; HET: MSE; 2.7A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.61  E-value=5.3e-06  Score=85.37  Aligned_cols=93  Identities=22%  Similarity=0.297  Sum_probs=66.7  Template_Neff=10.100

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ--NGIREAVSLLRR--TGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~--~IL~~Ll~lL~s--s~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +.++.++.++...++.++..++.++.++.....  ...+...  +.++.|+.++..  ..++.++..++.+|.+++....
T Consensus         9 ~~i~~lv~lL~~~~~~v~~~a~~~L~~l~~~~~--~~~l~~~~~~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~   86 (369)
T 6HB2_D            9 SQLNELVEFLHSPQPAVRQIAIDNLVGFSAGPT--SKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL   86 (369)
T ss_dssp             HHHHHHHGGGGCSCHHHHHHHHHHHGGGGSSGG--GGGGGHHHHHHHHHHHHHHHCTTTCCHHHHHHHHHHHHHHTTSHH
T ss_pred             hhHHHHHHHhcCCCHHHHHHHHHHHhHhcCCCC--chhhhcCCchHHHHHHHHHhCcccCcHHHHHHHHHHHHHHhCCHH
Confidence            456677777777777888899999988876543  2333333  478888888852  1356788899999999987655


Q NP_000290.2     363 LKEELI--A-DALPVLADRVII  381 (747)
Q Consensus       363 ~~~~Lv--e-giLe~Lv~LL~~  381 (747)
                      ....+.  + ++++.|+.++..
T Consensus        87 ~~~~l~~~~~g~i~~L~~ll~~  108 (369)
T 6HB2_D           87 VRNIILSDDKKFLKFLVWKIVD  108 (369)
T ss_dssp             HHHCCCCCCTHHHHHHHHHHSC
T ss_pred             HHHHHhhcChHHHHHHHHHHHc
Confidence            556666  5 888888888874


No 155
>2W3C_A GENERAL VESICULAR TRANSPORT FACTOR P115; MEMBRANE VESICLE TETHERING, ARMADILLO FOLD; HET: PEG; 2.22A {HOMO SAPIENS}
Probab=96.59  E-value=5.7e-06  Score=90.00  Aligned_cols=135  Identities=13%  Similarity=0.124  Sum_probs=95.4  Template_Neff=10.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE-SAKQQVY-QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~-~~~~~li-~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++.++.++.+.+..++..++.+|..++...+ .....+. ..+.++.++.++.+.+..++..++.+|..++........
T Consensus        71 ~i~~L~~ll~~~~~~v~~~a~~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~~~~~~~~~a~~~L~~l~~~~~~~~~  150 (577)
T 2W3C_A           71 NVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQK  150 (577)
T ss_dssp             HHHHHHHHTTCCCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGGCSSHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHHhchHHHHHHHHhCCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHH
Confidence            45566666766778889999999999987543 2222333 246788888888877788899999999999875444444


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSSTDELKEEL-IA-DALPVLADRVII  381 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas~~~~~~~L-ve-giLe~Lv~LL~~  381 (747)
                      .+...+.++.|+.++. ...    ..++..++.+|.+++........+ .+ ++++.|+.+|..
T Consensus       151 ~~~~~g~~~~L~~ll~-~~~~~~~~~v~~~al~~L~~l~~~~~~~~~~~~~~~~i~~L~~lL~~  213 (577)
T 2W3C_A          151 IVAFENAFERLLDIIS-EEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEV  213 (577)
T ss_dssp             HHHHTTHHHHHHHHHH-HTTGGGSCHHHHHHHHHHHHHHTTCHHHHHHHHHTTCGGGGSGGGCC
T ss_pred             HHHcCCHHHHHHHHHH-HhCCCCCcHHHHHHHHHHHHHHccCHHHHHHHHhcChHHHHHHHHhc
Confidence            4444678888888886 322    257788899999998765433333 34 788889888875


No 156
>4XZR_B Heh1-NLS, Kap60; karyopherins  nuclear import ; 2.25A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.58  E-value=5.2e-06  Score=81.38  Aligned_cols=114  Identities=19%  Similarity=0.154  Sum_probs=76.5  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++..........
T Consensus       172 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  251 (423)
T 4XZR_B          172 ALPTLAKLIYSMDTETLVDACWAISYLSDGPQEAIQAVIDVRIPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVV  251 (423)
T ss_dssp             GHHHHHHHTTCSCHHHHHHHHHHHHHHTSSSHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888888888876544333334444567777777777777888889999988876543332223


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       252 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  285 (423)
T 4XZR_B          252 INAGVLPALRLLLS-SPKENIKKEACWTISNITAG  285 (423)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHTTS
T ss_pred             HHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcC
Confidence            33356667777775 45667777888888877764


No 157
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=96.56  E-value=6e-06  Score=75.59  Aligned_cols=136  Identities=22%  Similarity=0.238  Sum_probs=88.7  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+..++.+.+..++..++.+|.+++.........+...+.++.++.++. ..+..++..++.++.+++... .....
T Consensus        53 ~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~-~~~~~  131 (233)
T 3TT9_A           53 GILKLLQLLKVQNEDVQRAVCGALRNLVFEDNDNKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLWNLSSND-KLKNL  131 (233)
T ss_dssp             HHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTSG-GGHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCCcHHHHHHHcccHHHHHHHHhhCCCHHHHHHHHHHHHHHccCH-HHHHH
Confidence            4556666676667788889999999988644444444555577788888887 556778888999999987643 22233


Q NP_000290.2     325 TRRQNGIREAVSLLRRT--------------GNAEIQKQLTGLLWNLSS-TDELKEELIA-DA-LPVLADRVIIP  382 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss--------------~d~eVr~~AL~aLsnLas-~~~~~~~Lve-gi-Le~Lv~LL~~~  382 (747)
                      +...+++..+..++...              .+..++..++.++.+++. .......+.. +. ++.|+.++...
T Consensus       132 ~~~~~~~~~l~~ll~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~  206 (233)
T 3TT9_A          132 MITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLVHYVRGT  206 (233)
T ss_dssp             HHHHHHHHHCCCCCHHHHCCCGGGCCCCCTTCCHHHHHHHHHHHHHHTTSCHHHHHHHHTSTTHHHHHHHHHHHH
T ss_pred             hhhhcHHHHHHHHHhhccCCCCCCCCcccCCCcHHHHHHHHHHHHHHHhcCHHHHHHHHHcccHHHHHHHHHHcc
Confidence            33334455555554311              135677888899999887 4444444444 55 78888877653


No 158
>6HB3_B Protein HGH1; solenoid protein, Armadillo repeat, CHAPERONE; 3.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=96.56  E-value=6.6e-06  Score=84.61  Aligned_cols=93  Identities=22%  Similarity=0.297  Sum_probs=66.7  Template_Neff=10.100

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ--NGIREAVSLLRR--TGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~--~IL~~Ll~lL~s--s~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +.++.++.++...+..++..++.++.++.....  ...+...  +.++.|+.++..  ..+..++..++.+|.+++....
T Consensus         9 ~~~~~lv~lL~~~~~~v~~~a~~~L~~l~~~~~--~~~l~~~~~~~i~~Lv~ll~~~~~~~~~~~~~al~~L~~l~~~~~   86 (369)
T 6HB3_B            9 SQLNELVEFLHSPQPAVRQIAIDNLVGFSAGPT--SKVFKNDSYRPIKDIIKMIMDPEHGTRVIIQQGVTILVNLSEDKL   86 (369)
T ss_pred             CcHHHHHHHccCCCHHHHHHHHHHHHHHcCChh--HHHHHHhCCCcHHHHHHHHhCCCCCCHHHHHHHHHHHHHHcCCHH
Confidence            456677777776677888899999988876543  2333333  478888888852  1356788899999999987655


Q NP_000290.2     363 LKEELI--A-DALPVLADRVII  381 (747)
Q Consensus       363 ~~~~Lv--e-giLe~Lv~LL~~  381 (747)
                      ....+.  . ++++.|+.+|..
T Consensus        87 ~~~~l~~~~~g~i~~L~~ll~~  108 (369)
T 6HB3_B           87 VRNIILSDDKKFLKFLVWKIVD  108 (369)
T ss_pred             HHHHHHhccCCcHHHHHHHhcC
Confidence            556666  5 888888888874


No 159
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=96.54  E-value=6.4e-06  Score=88.93  Aligned_cols=322  Identities=20%  Similarity=0.248  Sum_probs=204.5  Template_Neff=11.900

Q NP_000290.2     286 LGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELK  364 (747)
Q Consensus       286 ~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~  364 (747)
                      ...++.+...+...+..++..++.+|..++.........+...++++.+...+. ..++.++..++.++..++... ...
T Consensus       177 ~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~L~~l~~~~~~~~  255 (671)
T 6SA8_A          177 KKILKDLVKKLSSPNENELQNALWTLGNIASGGNEQIQAVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQI  255 (671)
T ss_dssp             HHHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTSCHHHH
T ss_pred             HHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCcHHHHHHHHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChHHH
Confidence            355667777777777778888888888887654333333444567777888886 557788999999999988743 222


Q NP_000290.2     365 EELIA-DALPVLADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQT  443 (747)
Q Consensus       365 ~~Lve-giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  443 (747)
                      ..+.. ++++.|+.++..                .++++-..+..+|..-.         ..           ....+..
T Consensus       256 ~~~~~~~~~~~l~~~l~~----------------~~~~v~~~a~~~L~~l~---------~~-----------~~~~~~~  299 (671)
T 6SA8_A          256 QAVIDAGALPALVQLLSS----------------PNEQILQEALWALSNIA---------SG-----------GNEQIQA  299 (671)
T ss_dssp             HHHHHTTCHHHHHHHTTC----------------SCHHHHHHHHHHHHHHT---------TS-----------CHHHHHH
T ss_pred             HHHHHcCHHHHHHHHhcC----------------CCHHHHHHHHHHHHHHH---------cC-----------CcHHHHH
Confidence            33333 677777777753                13444444444443211         00           0001111


Q NP_000290.2     444 MRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMN  523 (747)
Q Consensus       444 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  523 (747)
                      . -..++++.|+..++.      .+..-...+...|.++....                                     
T Consensus       300 ~-~~~~~~~~L~~~l~~------~~~~v~~~a~~~L~~l~~~~-------------------------------------  335 (671)
T 6SA8_A          300 V-IDAGALPALVQLLSS------PNEQILQEALWALSNIASGG-------------------------------------  335 (671)
T ss_dssp             H-HHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSC-------------------------------------
T ss_pred             H-HHhChHHHHHHHhcC------CcHHHHHHHHHHHHHHhcCC-------------------------------------
Confidence            1 113455555544431      11112222333333332110                                     


Q NP_000290.2     524 NNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARL  603 (747)
Q Consensus       524 ~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~L  603 (747)
                                   ......+.+.++++.|+.++. ..++.++..++.+|.+++...+.     ....+...++++.|+.+
T Consensus       336 -------------~~~~~~~~~~~~l~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~  396 (671)
T 6SA8_A          336 -------------NEQIQAVIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNE-----QIQAVIDAGALPALVQL  396 (671)
T ss_dssp             -------------HHHHHHHHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHG
T ss_pred             -------------cHHHHHHHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCcH-----HHHHHHHcCcHHHHHHH
Confidence                         001112345667888888887 46778888999999999874332     23333456788899999


Q NP_000290.2     604 LQSGNSDVVRSGASLLSNMSRHP-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS  681 (747)
Q Consensus       604 L~s~d~eVr~~AL~aLsnLa~~~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve  681 (747)
                      +.+.++.++..++.+|.+++... .. ......++++.|+.++.+      .++.++..++.+|.+++...+.....+.+
T Consensus       397 l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~L~~~l~~------~~~~v~~~a~~~L~~l~~~~~~~~~~~~~  470 (671)
T 6SA8_A          397 LSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQIQAVID  470 (671)
T ss_dssp             GGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHHTSCHHHHHHHHH
T ss_pred             hcCCCHHHHHHHHHHHHhhcCCCHHHHHHHHhcCcHHHHHHHcCC------CCHHHHHHHHHHHHHHHcCChHHHHHHHh
Confidence            98888899999999999998762 22 233445678888888876      36788999999999999765544455556


Q NP_000290.2     682 SSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       682 ~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      .++++.|+.++.+. ++.++..++.+|.+++..
T Consensus       471 ~~~~~~l~~~l~~~-~~~v~~~a~~~l~~l~~~  502 (671)
T 6SA8_A          471 AGALPALVQLLSSP-NEQIQDEAEKTLLNIANG  502 (671)
T ss_dssp             TTHHHHHHHHTTCS-CHHHHHHHHHHHHHHHTS
T ss_pred             cCcHHHHHHHhhCC-CHHHHHHHHHHHHHHHcC
Confidence            67788888888876 788899999999998854


No 160
>1EE4_A KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=96.51  E-value=6.8e-06  Score=80.51  Aligned_cols=114  Identities=22%  Similarity=0.183  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..............++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       214 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  293 (423)
T 1EE4_A          214 IPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAV  293 (423)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCcchhHHHHHHHHHHHhCChHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            44556666666677888889999988876543333333334667777777777777888899999988876544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       294 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  327 (423)
T 1EE4_A          294 IDANLIPPLVKLLE-VAEDKTKKEACWAISNASSG  327 (423)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHGG
T ss_pred             HHCCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHcC
Confidence            34456677777775 55667788888888887764


No 161
>1EE4_B KARYOPHERIN ALPHA; ARM repeat, TRANSPORT PROTEIN; 2.1A {Saccharomyces cerevisiae} SCOP: a.118.1.1
Probab=96.51  E-value=6.8e-06  Score=80.51  Aligned_cols=114  Identities=22%  Similarity=0.183  Sum_probs=77.4  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..............++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       214 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  293 (423)
T 1EE4_B          214 IPKRLVELLSHESTLVQTPALRAVGNIVTGNDLQTQVVINAGVLPALRLLLSSPKENIKKEACWTISNITAGNTEQIQAV  293 (423)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCcchhHHHHHHHHHHHhCChHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            44556666666677888889999988876543333333334667777777777777888899999988876544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       294 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  327 (423)
T 1EE4_B          294 IDANLIPPLVKLLE-VAEDKTKKEACWAISNASSG  327 (423)
T ss_dssp             HHTTCHHHHHHHHH-HSCHHHHHHHHHHHHHHHGG
T ss_pred             HHCCcHHHHHHHHh-cCCHHHHHHHHHHHHHHHcC
Confidence            34456677777775 55667788888888887764


No 162
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=96.45  E-value=9.9e-06  Score=98.55  Aligned_cols=150  Identities=9%  Similarity=0.041  Sum_probs=112.4  Template_Neff=9.500

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.|+.+|. +.++.++..|+.+|..++....       ...+.+.. ++.|+.+|.+.++.++..++.+|++|+..
T Consensus       618 ~~~l~~L~~~l~-d~~~~vR~~a~~al~~l~~~~~-------~~~~~~~~-lp~L~~lL~d~~~~vr~~al~aL~~L~~~  688 (1454)
T 5KC2_B          618 DIILSHLITYLN-DKDPALRVSLIQTISGISILLG-------TVTLEQYI-LPLLIQTITDSEELVVISVLQSLKSLFKT  688 (1454)
T ss_pred             hhhHHHHHHHcc-CCCHHHHHHHHHHHHHHHHhhH-------HHHHHHcC-HHHHHHHhcCCCHHHHHHHHHHHHHHhhC
Confidence            346788889998 5888999999999999986431       22223333 89999999988889999999999999876


Q NP_000290.2     626 P-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      . .....+.. +++.+..++.+      .++.++..++.+|..|+.....  .... ..+++.|+.+|.+. +..+++.|
T Consensus       689 ~~~~~~~~~~-~l~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~--~~~~-~~~~~~L~~~L~d~-~~~vr~~a  757 (1454)
T 5KC2_B          689 GLIRKKYYID-ISKTTSPLLLH------PNNWIRQFTLMIIIEIINKLSK--AEVY-CILYPIIRPFFEFD-VEFNFKSM  757 (1454)
T ss_pred             CHHHHHHHHH-HHHHHHHHHCC------CCHHHHHHHHHHHHHHhcCCCC--HHHH-cChHHHHHHHhcCC-CHHHHHHH
Confidence            3 22222222 66777777766      3788999999999999875321  1122 45788899999877 88999999


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.+|..++..+
T Consensus       758 ~~~L~~~~~~~  768 (1454)
T 5KC2_B          758 ISCCKQPVSRS  768 (1454)
T ss_pred             HHHHHHHhhcc
Confidence            99999988765


No 163
>4B18_A IMPORTIN SUBUNIT ALPHA-1, TELOMERASE REVERSE; TRANSPORT PROTEIN - PEPTIDE COMPLEX; 2.52A {HOMO SAPIENS}
Probab=96.44  E-value=8.9e-06  Score=80.74  Aligned_cols=366  Identities=18%  Similarity=0.167  Sum_probs=217.7  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.. .++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++........
T Consensus        61 ~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~  140 (447)
T 4B18_A           61 GVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD  140 (447)
T ss_dssp             THHHHHHHHTTCTTCHHHHHHHHHHHHHHTSSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             cHHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCcHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHHccChhHHH
Confidence            345556666655 5677888889999888765433333333456777888888777788889999999988765443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      .+...++++.+...+....++.++..++.++..++...........  ++++.+..++..                .+++
T Consensus       141 ~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~  204 (447)
T 4B18_A          141 YVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV----------------SDTD  204 (447)
T ss_dssp             HHHHTTCHHHHHHGGGCTTCHHHHHHHHHHHHHHHCCSSSCCCHHHHGGGHHHHHHHTTS----------------CCHH
T ss_pred             HHHHCCcHHHHHHHhhcCCChhHHHHHHHHHHHHhcCCCCCCcccccccHHHHHHHHhhC----------------CCHH
Confidence            3334456777777775333457888888999888765432222211  455556655532                1334


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN  481 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  481 (747)
                      +...+..++..-...      -+              ...+.+. -.+++..|...+..      .+..-.+.+...|.+
T Consensus       205 ~~~~a~~~l~~l~~~------~~--------------~~~~~~~-~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~  257 (447)
T 4B18_A          205 VLADACWALSYLSDG------PN--------------DKIQAVI-DAGVCRRLVELLMH------NDYKVVSPALRAVGN  257 (447)
T ss_dssp             HHHHHHHHHHHHTSS------SH--------------HHHHHHH-HTTCHHHHHHHTTC------SCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcC------CH--------------HHHHHHH-HCCHHHHHHHHHcC------CCHHHHHHHHHHHHH
Confidence            444444333221100      00              0000000 12333333333321      111112222222322


Q NP_000290.2     482 LSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK  561 (747)
Q Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d  561 (747)
                      +....                                                  ......+.+.++++.|+.++. +.+
T Consensus       258 l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~  286 (447)
T 4B18_A          258 IVTGD--------------------------------------------------DIQTQVILNCSALQSLLHLLS-SPK  286 (447)
T ss_dssp             HTTSC--------------------------------------------------HHHHHHHHHTTHHHHHHHHTT-CSS
T ss_pred             HhcCC--------------------------------------------------hHHHHHHhhcchHHHHHHHhc-CCC
Confidence            22110                                                  000112234567888888887 467


Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFP  638 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~  638 (747)
                      +.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++..  ... ..+...++++
T Consensus       287 ~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~  361 (447)
T 4B18_A          287 ESIKKEACWTISNITAGNRA-----QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK  361 (447)
T ss_dssp             HHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHH
T ss_pred             HHHHHHHHHHHHHHhcCCHH-----HHHHHHhCChHHHHHHHHhcCCHHHHHHHHHHHHHHhccCCHHHHHHHHHCCcHH
Confidence            78888999999999875332     223334567888899998888888999999999999875  222 2334446778


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-----------QYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-----------~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .+..++.+      .++.++..++.+|.+++...+....           .+.+.++++.+..++.+. ++.++..++.+
T Consensus       362 ~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~-~~~v~~~a~~~  434 (447)
T 4B18_A          362 PLCDLLTV------MDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHE-NQEIYQKAFDL  434 (447)
T ss_dssp             HHHHGGGS------SCHHHHHHHHHHHHHHHHHHHHHHHHSSCCSCHHHHHHHHTTHHHHHHHGGGSS-CHHHHHHHHHH
T ss_pred             HHHHHhhC------CCHHHHHHHHHHHHHHHHHhHHHHhhCCCCCCHHHHHHHHhccHHHHHHHHhCC-CHHHHHHHHHH
Confidence            88888776      3678889999999999875332221           233445677777777666 77889999999


Q NP_000290.2     708 LSDMWSSKE  716 (747)
Q Consensus       708 LsnL~~~~~  716 (747)
                      +.++....+
T Consensus       435 l~~l~~~~~  443 (447)
T 4B18_A          435 IEHYFGTED  443 (447)
T ss_dssp             HHHHCC---
T ss_pred             HHHHhcCcc
Confidence            988876543


No 164
>1JDH_A BETA-CATENIN, hTcf-4; BETA-CATENIN, TCF4, PROTEIN-PROTEIN COMPLEX, TRANSCRIPTION; 1.9A {Homo sapiens} SCOP: a.118.1.1
Probab=96.44  E-value=9e-06  Score=82.47  Aligned_cols=363  Identities=19%  Similarity=0.190  Sum_probs=216.7  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+... +..++..++.++..+..... ...
T Consensus       143 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~-~~~  221 (529)
T 1JDH_A          143 GGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSS-NKP  221 (529)
T ss_dssp             THHHHHHHGGGCCCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTT-HHH
T ss_pred             ChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChhHHHHHHHccCCcHHHHHHHHHHHHHHhcCCc-cHH
Confidence            3455666667667788888999999988754444333444455777777777654 56778888888888875432 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      .+...++++.+...+. ..++.++..++.++..++....... ...++++.+..++..                -++++.
T Consensus       222 ~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~-~~~~~~~~l~~~l~~----------------~~~~~~  283 (529)
T 1JDH_A          222 AIVEAGGMQALGLHLT-DPSQRLVQNCLWTLRNLSDAATKQE-GMEGLLGTLVQLLGS----------------DDINVV  283 (529)
T ss_dssp             HHHHTTHHHHHHTTTT-SSCHHHHHHHHHHHHHHHTTCTTCS-CCHHHHHHHHHHTTC----------------SCHHHH
T ss_pred             HHHHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHcchhhhHH-HHchHHHHHHHHhCC----------------CCHHHH
Confidence            3333456777777776 4566788888888888876432211 112455556655541                123333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-...      .+.              .+..+ .-.+.++.++..+..    ..-+..-.+.+...|.++.
T Consensus       284 ~~a~~~l~~l~~~------~~~--------------~~~~~-~~~~~~~~l~~~l~~----~~~~~~~~~~a~~~l~~l~  338 (529)
T 1JDH_A          284 TCAAGILSNLTCN------NYK--------------NKMMV-CQVGGIEALVRTVLR----AGDREDITEPAICALRHLT  338 (529)
T ss_dssp             HHHHHHHHHHTTT------CHH--------------HHHHH-HHTTHHHHHHHHHHH----HTTCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHhcC------CHH--------------HHHHH-HHcCHHHHHHHHHHh----cCCChHhHHHHHHHHHHHh
Confidence            3333333221100      000              00000 012233333332211    0111222333444444443


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      .......                                               .....+...++++.++.++....++.
T Consensus       339 ~~~~~~~-----------------------------------------------~~~~~~~~~~~~~~l~~~l~~~~~~~  371 (529)
T 1JDH_A          339 SRHQEAE-----------------------------------------------MAQNAVRLHYGLPVVVKLLHPPSHWP  371 (529)
T ss_dssp             SSSTTHH-----------------------------------------------HHHHHHHHTTCHHHHHHTTSTTCCHH
T ss_pred             cCcccHH-----------------------------------------------HHHHHHHhcccHHHHHHHHCCCCCHH
Confidence            2211000                                               00111234566778888887323667


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN----------------------SDVVRSGASLLSN  621 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d----------------------~eVr~~AL~aLsn  621 (747)
                      ++..++.+|.+++....      ....+...++++.|..++.+.+                      +.++..++.+|.+
T Consensus       372 ~~~~a~~~l~~l~~~~~------~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~  445 (529)
T 1JDH_A          372 LIKATVGLIRNLALCPA------NHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHI  445 (529)
T ss_dssp             HHHHHHHHHHHHTTSGG------GHHHHHHTTHHHHHHHHHHHHHHHHC-----------CBTTBCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcChh------hhHHHHhcCHHHHHHHHHHhcChhHHHHHhccCcchhHhccCCHHHHHHHHHHHHHH
Confidence            88889999999887532      1333345678888888887654                      6788889999999


Q NP_000290.2     622 MSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       622 La~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ++..... ..+...++++.+..++.+      .++.++..++.+|.+++.. +.....+...++++.|..++.+. ++.+
T Consensus       446 l~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~v  517 (529)
T 1JDH_A          446 LARDVHNRIVIRGLNTIPLFVQLLYS------PIENIQRVAAGVLCELAQD-KEAAEAIEAEGATAPLTELLHSR-NEGV  517 (529)
T ss_dssp             HTTSHHHHHHHHHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHTTS-HHHHHHHHHTTCHHHHHHGGGCS-SHHH
T ss_pred             HhcCccchHHHHhcCcHHHHHHHhcC------CCHHHHHHHHHHHHHHhcC-HHHHHHHHHcCcHHHHHHHHhcC-CHHH
Confidence            9876433 233445677888888876      3678899999999999875 44455555667888899988876 7889


Q NP_000290.2     701 AEAARLLLSDMW  712 (747)
Q Consensus       701 r~aAL~aLsnL~  712 (747)
                      +..++.+|.+++
T Consensus       518 ~~~a~~~L~~l~  529 (529)
T 1JDH_A          518 ATYAAAVLFRMS  529 (529)
T ss_dssp             HHHHHHHHHHHC
T ss_pred             HHHHHHHHHhcC
Confidence            999999888763


No 165
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=96.43  E-value=9.2e-06  Score=73.31  Aligned_cols=135  Identities=19%  Similarity=0.216  Sum_probs=90.0  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++.++....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        88 ~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  167 (243)
T 5MFI_B           88 GALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQK  167 (243)
T ss_dssp             TCHHHHHHHTSSSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             CcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34555666666667778888999999887644443334444567777888887777788888999998888644433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       168 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  224 (243)
T 5MFI_B          168 LIEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLEEAGAEPALEKLQS  224 (243)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHGGG
T ss_pred             HHHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhc
Confidence            334456777777776 5567888889999999886332 2222333 56666666654


No 166
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=96.43  E-value=9.2e-06  Score=73.31  Aligned_cols=135  Identities=19%  Similarity=0.216  Sum_probs=90.0  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++.++....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus        88 ~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  167 (243)
T 5MFJ_B           88 GALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQK  167 (243)
T ss_dssp             TCHHHHHHHHHHSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHH
T ss_pred             CcHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34555666666667778888999999887644443334444567777888887777788888999998888644433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       168 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  224 (243)
T 5MFJ_B          168 LIEAGALSPLVKLLD-DASEEVIQEAVWAIANIASGNNEQIQKLEEAGAEPALEKLQS  224 (243)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHTSS
T ss_pred             HHHCCcHHHHHHHcc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHhc
Confidence            334456777777776 5567888889999999886332 2222333 56666666654


No 167
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=96.43  E-value=1.1e-05  Score=87.33  Aligned_cols=182  Identities=12%  Similarity=0.061  Sum_probs=127.6  Template_Neff=8.700

Q NP_000290.2     539 GSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLM----SSGMSQLIGLKEKGLPQIARLLQS------GN  608 (747)
Q Consensus       539 ~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~----s~~~~~~llie~giI~~Ll~LL~s------~d  608 (747)
                      ....+++.|+++.|+.+|. +++..+...++.+|.+++......    ........+.+.++++.|+.+|..      .+
T Consensus        60 ~~~~lv~~g~i~~Lv~LL~-~~n~~i~~~a~~~L~~Lt~~~~~~~~~~~~~~~~~~l~~~g~l~~Lv~~L~~~~e~~~~d  138 (490)
T 4MFU_A           60 LYHLLVELNAVQSLLGLLG-HDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEE  138 (490)
T ss_dssp             CTHHHHHTTHHHHHHHHTS-CSSHHHHHHHHHHHHHHHHGGGSSCCCHHHHHHHHHHHHTTHHHHHHHHHHHCCTTCHHH
T ss_pred             HHHHHHHCChHHHHHHHhC-CCCHHHHHHHHHHHHHHcCcccccCChhhHHHHHHHHHhCCHHHHHHHHHHhccccccch
Confidence            3455678899999999998 466778888999999998643200    000013344577889999998875      55


Q NP_000290.2     609 SDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLN  686 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~  686 (747)
                      ...+..++.+|.+|+.. +.. ..+...++++.|+.++....    ....++..++.+|.+|+..++..+..+.+.++++
T Consensus       139 ~~~~~~al~~L~nL~~~~~~~~~~i~~~~~l~~Ll~~L~~~~----~~~~~k~~a~~~L~~L~~~~~~~~~~l~~~g~i~  214 (490)
T 4MFU_A          139 ADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKM----PFDANKLYCSEVLAILLQDNDENRELLGELDGID  214 (490)
T ss_dssp             HHHHHHHHHHHHHHHHHSTTHHHHHCCCCCHHHHHHHHHCCS----CCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHH
T ss_pred             HHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHHHHcCC----CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHH
Confidence            67888999999999976 333 33445678888988887620    1367788999999999986566667777778899


Q NP_000290.2     687 NIINLCRS-----SA---SPKAAEAARLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       687 ~Ll~LL~s-----~~---d~eVr~aAL~aLsnL~~~~~~~~~~~~~~  725 (747)
                      .|+.++..     +.   .......++.+|.+++...+.+..+.+.|
T Consensus       215 ~Ll~lL~~~~~~d~~~~~~~e~~en~~~aL~~L~~~~~~~~~f~~~~  261 (490)
T 4MFU_A          215 VLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGE  261 (490)
T ss_dssp             HHHHHHHTTSSSCCSSHHHHHHHHHHHHHHHHHHHSTHHHHHHHHTT
T ss_pred             HHHHHHHhhhhcCCCCHHHHHHHHHHHHHHHHHhCCHHHHHHHHHCC
Confidence            99998851     11   12344556889999887776655554443


No 168
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=96.41  E-value=1e-05  Score=74.57  Aligned_cols=134  Identities=26%  Similarity=0.306  Sum_probs=85.5  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++..........
T Consensus        89 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  168 (286)
T 5AEI_B           89 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  168 (286)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHhCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCChHHHHHH
Confidence            44556666666677788888999888876533333333344567777777777777888889999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  224 (286)
T 5AEI_B          169 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLS  224 (286)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHcc
Confidence            33456677777775 4566778888888888876422 2222222 45565655554


No 169
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=96.39  E-value=1.1e-05  Score=74.12  Aligned_cols=111  Identities=25%  Similarity=0.289  Sum_probs=73.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+...+.+.++.++..++.++..++...+.....+
T Consensus       170 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  249 (281)
T 4PLS_B          170 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAV  249 (281)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCcHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHccCCCHHHHHHHHHHHHHHHcCChhHHHHH
Confidence            45556666666677888889999988876544333333444577777787877777888899999998885544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNL  357 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnL  357 (747)
                      ...++++.+...+. ..++.++..++.++..+
T Consensus       250 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l  280 (281)
T 4PLS_B          250 KEAGAEPALEQLQS-SPNEKIQKEAQEALEKI  280 (281)
T ss_dssp             HTTTHHHHHHTTTS-CSCHHHHHHHHHHHHHC
T ss_pred             HHCChHHHHHHHhc-CCCHHHHHHHHHHHHhh
Confidence            33356666666665 45666777777666554


No 170
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=96.38  E-value=1.4e-05  Score=88.57  Aligned_cols=181  Identities=12%  Similarity=0.075  Sum_probs=128.1  Template_Neff=8.100

Q NP_000290.2     539 GSGWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSS---G--MSQLIGLKEKGLPQIARLLQS------G  607 (747)
Q Consensus       539 ~~~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~---~--~~~~llie~giI~~Ll~LL~s------~  607 (747)
                      ....+++.|+++.|+.+|. +.+..++..++.+|.+|+..... ..   .  .....+.+.++++.|+.+|..      .
T Consensus       138 ~~~~lv~~g~i~~Lv~LL~-~~n~di~~~a~~~L~~Lt~~~~~-~~~~~~~~~l~~~l~e~g~l~~Lv~~L~~l~e~~~~  215 (568)
T 4HM9_A          138 LYHLLVELNAVQSLLGLLG-HDNTDVSIAVVDLLQELTDIDTL-HESEEGAEVLIDALVDGQVVALLVQNLERLDESVKE  215 (568)
T ss_dssp             GHHHHHHTTHHHHHHHGGG-CSSHHHHHHHHHHHHHHTCHHHH-TTCHHHHHHHHHHHHHTTHHHHHHHHHTTCCTTSHH
T ss_pred             HHHHHHHCChHHHHHHHhC-CCCHHHHHHHHHHHHHHhCCccc-cCChhhHHHHHHHHHhCCHHHHHHHHHhcccccccc
Confidence            4455678899999999998 46678888999999999864320 00   0  013344567889999998876      5


Q NP_000290.2     608 NSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSML  685 (747)
Q Consensus       608 d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL  685 (747)
                      +...+..++.+|.+|+.. +.. ..+...++++.|+.++....    .....+..|+.+|.+|+..++..+..+.+.+++
T Consensus       216 d~~~~~~al~iL~nL~~~~~~~~~~i~~~g~l~~Ll~lL~~~~----~~~~~k~~AaeiL~~L~~~~~~~r~~l~~~g~I  291 (568)
T 4HM9_A          216 EADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKM----PFDANKLYCSEVLAILLQDNDENRELLGELDGI  291 (568)
T ss_dssp             HHHHHHHHHHHHHHHHHHCGGGHHHHCCCCCHHHHHHHHHSSC----CCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHH
T ss_pred             hHHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHHHHcCC----CCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchH
Confidence            567888999999999975 333 23445678888998887520    145678889999999998656677777778889


Q NP_000290.2     686 NNIINLCRS-----SA---SPKAAEAARLLLSDMWSSKELQGVLRQQG  725 (747)
Q Consensus       686 ~~Ll~LL~s-----~~---d~eVr~aAL~aLsnL~~~~~~~~~~~~~~  725 (747)
                      +.|+.++..     ..   .....+.++.+|..++...+.+..+...|
T Consensus       292 ~~LL~lL~~y~~~d~~~~~e~e~~en~~~aL~~L~~~~~~r~~f~~~~  339 (568)
T 4HM9_A          292 DVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGE  339 (568)
T ss_dssp             HHHHHHHGGGTTSCCSSSHHHHHHHHHHHHHHHHTTSTHHHHHHHHTT
T ss_pred             HHHHHHHHhhhccCCCCHHHHHHHHHHHHHHHHHhCCHHHHHHHHHCC
Confidence            999998851     11   12345566889999888776655444443


No 171
>3L6X_A Catenin delta-1, E-cadherin; p120, catenin, cadherin, E-cadherin, armadillo; HET: SO4; 2.4A {Homo sapiens}
Probab=96.36  E-value=1.3e-05  Score=86.31  Aligned_cols=135  Identities=19%  Similarity=0.251  Sum_probs=86.7  Template_Neff=11.000

Q NP_000290.2     246 TIPKAVQYLSS------QDEKYQAIGAYYIQHTCFQDE-------------------------SAKQQVYQLGGICKLVD  294 (747)
Q Consensus       246 iL~~Ll~lL~s------sd~eVr~sAL~aLsnLs~~~~-------------------------~~~~~li~~~IL~~Ll~  294 (747)
                      +++.++.++..      .+..++..++.+|.+++....                         .....+...++++.+..
T Consensus       236 ~v~~L~~~l~~~~~~~~~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~  315 (584)
T 3L6X_A          236 LVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIPQAERYQEAAPNVANNTGTSPARGYELLFQPEVVRIYIS  315 (584)
T ss_dssp             HHHHHHHHHHHHHHTTCCSCHHHHHHHHHHHHHHTTHHHHSTTCCC--------------CCCCGGGGGGSHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcCCCCChHHHHHHHHHHHHHHhhhhccChhHHHHHHhcCcCCCCCCCCChhhhhHhhChhHHHHHHH
Confidence            34555565553      356677888888888875421                         11223334567777777


Q NP_000290.2     295 LLRSP-NQNVQQAAAGALRNLVFRS----TTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA  369 (747)
Q Consensus       295 lL~s~-d~eVr~~AL~aLs~La~~~----~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve  369 (747)
                      ++... ++.++..++.+|.+++...    ......+...++++.+..++. ..+..++..++.+|.+++........+..
T Consensus       316 ll~~~~~~~~~~~a~~~L~~L~~~~~~~~~~~~~~~~~~~~l~~L~~ll~-~~~~~v~~~a~~~L~~L~~~~~~~~~l~~  394 (584)
T 3L6X_A          316 LLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLT-NEHERVVKAASGALRNLAVDARNKELIGK  394 (584)
T ss_dssp             HHHHCCCHHHHHHHHHHHHHHHSSCSHHHHHHHHHHTSHHHHHHHHHGGG-CSCHHHHHHHHHHHHHHHTTCSCHHHHHH
T ss_pred             HHHcCCCHHHHHHHHHHHHHHhCCCccCCHHHHHHHHHcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcChHHHHHHHc
Confidence            77765 7788889999999987642    222233334467778888886 56678888999999999876444333333


Q NP_000290.2     370 DALPVLADRVII  381 (747)
Q Consensus       370 giLe~Lv~LL~~  381 (747)
                      ++++.|+.+|..
T Consensus       395 ~~l~~L~~~L~~  406 (584)
T 3L6X_A          395 HAIPNLVKNLPG  406 (584)
T ss_dssp             HHHHHHHHTSSS
T ss_pred             chHHHHHHcCCC
Confidence            566666666643


No 172
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=96.35  E-value=1.2e-05  Score=78.71  Aligned_cols=134  Identities=17%  Similarity=0.197  Sum_probs=87.3  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..++...+.....+...++++.+..++.+.++.++..++.++..++...+.....+
T Consensus       223 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  302 (426)
T 4U5L_A          223 VVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQV  302 (426)
T ss_dssp             CHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTGGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCccHHHHHHHHHHHHhcCCHHHHHHHhccchHHHHHHHhcCCChHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666666777888889999998886544333344445677778888877778888899999998886544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD--ELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~--~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++...  .....+.. ++++.|..++.
T Consensus       303 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  359 (426)
T 4U5L_A          303 VNHGLVPFLVGVLS-KADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEPLMNLLS  359 (426)
T ss_dssp             HHTTCHHHHHHHHH-SSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHTTCHHHHHHGGG
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCCHHHHHHHHhCCcHHHHHHHhc
Confidence            33456777777776 456677888888888887631  11122222 45555555544


No 173
>2JDQ_A IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC; TRANSPORT, PB2 SUBUNIT, NUCLEAR PROTEIN; 2.2A {HOMO SAPIENS}
Probab=96.34  E-value=1.3e-05  Score=79.63  Aligned_cols=366  Identities=18%  Similarity=0.167  Sum_probs=218.3  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.. .++.++..++.++..++.........+...++++.+...+.+.+..++..++.++..++........
T Consensus        64 ~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~  143 (450)
T 2JDQ_A           64 GVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSSEFEDVQEQAVWALGNIAGDSTMCRD  143 (450)
T ss_dssp             THHHHHHHHHTCTTCHHHHHHHHHHHHHHHSSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             chHHHHHHHHccCCCHHHHHHHHHHHHHHhCCCcHHHHHHHHcChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCChHHHH
Confidence            345556666655 5677888888888888765443333333456777888888777788899999999988765443333


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIA--DALPVLADRVIIPFSGWCDGNSNMSREVVDPE  401 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~Lve--giLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~  401 (747)
                      .+...++++.+...+....++.++..++.++..++...........  ++++.+..++..                .+++
T Consensus       144 ~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~----------------~~~~  207 (450)
T 2JDQ_A          144 YVLDCNILPPLLQLFSKQNRLTMTRNAVWALSNLCRGKSPPPEFAKVSPCLNVLSWLLFV----------------SDTD  207 (450)
T ss_dssp             HHHHTTCHHHHHHHTTSCCCHHHHHHHHHHHHHHHCCSSSCCCGGGTGGGHHHHHHHTTC----------------CCHH
T ss_pred             HHHHCCCHHHHHHHHhhccchhHHHHHHHHHHHHhcCCCCCchhhhhhhHHHHHHHHhcC----------------CCHH
Confidence            3334566777777776333457888888999888765432222221  455556655543                1334


Q NP_000290.2     402 VFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHN  481 (747)
Q Consensus       402 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  481 (747)
                      +...+..+|..-...      .+              ...+.. -..+++..|...+++      -+..-.+.++..|.+
T Consensus       208 ~~~~a~~~l~~l~~~------~~--------------~~~~~~-~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~  260 (450)
T 2JDQ_A          208 VLADACWALSYLSDG------PN--------------DKIQAV-IDAGVCRRLVELLMH------NDYKVVSPALRAVGN  260 (450)
T ss_dssp             HHHHHHHHHHHHTSS------SH--------------HHHHHH-HHTTTHHHHHHHTTC------SCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcC------CH--------------HHHHHH-HHCCHHHHHHHHHcC------CCHHHHHHHHHHHHH
Confidence            444444333221000      00              000000 012344444433321      011111222222222


Q NP_000290.2     482 LSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKK  561 (747)
Q Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d  561 (747)
                      +...-                                                  ......+.+.++++.++.++. +.+
T Consensus       261 l~~~~--------------------------------------------------~~~~~~~~~~~~~~~l~~~l~-~~~  289 (450)
T 2JDQ_A          261 IVTGD--------------------------------------------------DIQTQVILNCSALQSLLHLLS-SPK  289 (450)
T ss_dssp             HTTSC--------------------------------------------------HHHHHHHHTTTHHHHHHHHTT-CSS
T ss_pred             HhhCC--------------------------------------------------hHHHHHHhhcchHHHHHHHhc-CCC
Confidence            22100                                                  000112234567888888887 467


Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH--PLL-HRVMGNQVFP  638 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~--~e~-~~ll~~giI~  638 (747)
                      +.++..++.+|.+++.....     ....+...++++.|..++.+.++.++..++.+|.+++..  +.. ..+...++++
T Consensus       290 ~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~  364 (450)
T 2JDQ_A          290 ESIKKEACWTISNITAGNRA-----QIQTVIDANIFPALISILQTAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIK  364 (450)
T ss_dssp             HHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHH
T ss_pred             HHHHHHHHHHHHHHhcCCHH-----HHHHHHhCCHHHHHHHHHhcCCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHH
Confidence            78888999999999875332     223334567888899998888888999999999999876  222 2334456788


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-----------QYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-----------~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .+..++.+      .++.++..++.+|.+++...+....           .+.+.+.++.+..++.+. ++.++..++.+
T Consensus       365 ~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~l~~l~~~~-~~~v~~~a~~~  437 (450)
T 2JDQ_A          365 PLCDLLTV------MDSKIVQVALNGLENILRLGEQEAKRNGTGINPYCALIEEAYGLDKIEFLQSHE-NQEIYQKAFDL  437 (450)
T ss_dssp             HHHHGGGS------SCHHHHHHHHHHHHHHHHHHHHHHHHSCSCCCHHHHHHHHHHCHHHHHHHHCHH-HHHHHHHHHHH
T ss_pred             HHHHHhhC------CCHHHHHHHHHHHHHHHHHhHHHHhhCCCCCCHHHHHHHHhccHHHHHHHHhCC-CHHHHHHHHHH
Confidence            88888876      3678888999999999875332221           233445667776666665 77889999999


Q NP_000290.2     708 LSDMWSSKE  716 (747)
Q Consensus       708 LsnL~~~~~  716 (747)
                      +.++....+
T Consensus       438 l~~~~~~~~  446 (450)
T 2JDQ_A          438 IEHYFGTED  446 (450)
T ss_dssp             HHHHHCCC-
T ss_pred             HHHHhcCcc
Confidence            988876544


No 174
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=96.33  E-value=1.5e-05  Score=88.20  Aligned_cols=169  Identities=12%  Similarity=0.125  Sum_probs=105.6  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKK----DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-----DV--  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d----~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-----eV--  611 (747)
                      +++.|+++.|+.++.. ..    ..++..++.+|.+++..+..     ....+.+.++++.|..++...+.     ..  
T Consensus       204 l~~~g~~~~L~~ll~~-~~~~~~~~v~~~al~~L~~L~~~~~~-----~~~~~~e~~~i~~L~~lL~~~~~~~~~~~~~~  277 (651)
T 3GQ2_A          204 VAFENAFERLLDIITE-EGNSDGGIVVEDCLILLQNLLKNNNS-----NQNFFKEGSYIQRMKPWFEVGDENSGWSAQKV  277 (651)
T ss_dssp             HHHTTHHHHHHHHHHH-TTGGGSHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTCGGGTGGGGCCCSSCCCCCHHHH
T ss_pred             HHhCChHHHHHHHHHH-hCCCCccHHHHHHHHHHHHHHhCCHH-----HHHHHHhcChHHHHHHHHhcCCccCCCchHHH
Confidence            4577889999998873 32    25777899999999875432     34455567889999988874331     11  


Q NP_000290.2     612 --VRSGASLLSNMSRH-------PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS  681 (747)
Q Consensus       612 --r~~AL~aLsnLa~~-------~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve  681 (747)
                        ...++.++..++..       ... ..+...++++.|+.++....    .+..++..++.+|++++..++.....+.+
T Consensus       278 ~~~~~~~~il~~l~~~~~~~~~~~~~~~~l~~~g~l~~L~~ll~~~~----~~~~v~~~a~~~La~l~~~~~~~q~~~~~  353 (651)
T 3GQ2_A          278 TNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATG----VPADILTETINTVSEVIRGCQVNQDYFAS  353 (651)
T ss_dssp             HHHHHHHHHHHHHHCTTSCHHHHHHHHHHHHHTTHHHHHHHHHHCSS----CCHHHHHHHHHHHHHHHTTCHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHhCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHhcC----CCHHHHHHHHHHHHHHHhcCHHHHHHHHh
Confidence              22334444444421       112 23356678888888886520    14578889999999998865555444444


Q NP_000290.2     682 S--------SMLNNIINLCRSS-ASPKAAEAARLLLSDMWSS-KELQGVL  721 (747)
Q Consensus       682 ~--------giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~-~~~~~~~  721 (747)
                      .        +.+..|+.++... .+..++..++.+|.+++.. .+.+..+
T Consensus       354 ~~~~~~~~~~~l~~Ll~~l~~~~~~~~~r~~al~~L~~~~~~~~~~~~~l  403 (651)
T 3GQ2_A          354 VNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEI  403 (651)
T ss_dssp             CBCCSSSCCBHHHHHHHHHTCTTSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             CCCCCCCCchHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHhcCHHHHHHH
Confidence            2        2355666665432 1567888999999666653 3334333


No 175
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=96.33  E-value=1.5e-05  Score=88.20  Aligned_cols=169  Identities=12%  Similarity=0.125  Sum_probs=105.6  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKK----DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS-----DV--  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d----~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~-----eV--  611 (747)
                      +++.|+++.|+.++.. ..    ..++..++.+|.+++..+..     ....+.+.++++.|..++...+.     ..  
T Consensus       204 l~~~g~~~~L~~ll~~-~~~~~~~~v~~~al~~L~~L~~~~~~-----~~~~~~e~~~i~~L~~lL~~~~~~~~~~~~~~  277 (651)
T 3GRL_A          204 VAFENAFERLLDIITE-EGNSDGGIVVEDCLILLQNLLKNNNS-----NQNFFKEGSYIQRMKPWFEVGDENSGWSAQKV  277 (651)
T ss_dssp             HHHTTHHHHHHHHHHH-HTGGGSHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTCGGGGGGGGCCCSCSSCCCHHHH
T ss_pred             HHhCChHHHHHHHHHH-hCCCCccHHHHHHHHHHHHHHhCCHH-----HHHHHHhcChHHHHHHHHhcCCccCCCchHHH
Confidence            4577889999998873 32    25777899999999875432     34455567889999988874331     11  


Q NP_000290.2     612 --VRSGASLLSNMSRH-------PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS  681 (747)
Q Consensus       612 --r~~AL~aLsnLa~~-------~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve  681 (747)
                        ...++.++..++..       ... ..+...++++.|+.++....    .+..++..++.+|++++..++.....+.+
T Consensus       278 ~~~~~~~~il~~l~~~~~~~~~~~~~~~~l~~~g~l~~L~~ll~~~~----~~~~v~~~a~~~La~l~~~~~~~q~~~~~  353 (651)
T 3GRL_A          278 TNLHLMLQLVRVLVSPNNPPGATSSCQKAMFQCGLLQQLCTILMATG----VPADILTETINTVSEVIRGCQVNQDYFAS  353 (651)
T ss_dssp             HHHHHHHHHHHHHTCTTSCHHHHHHHHHHHHHTTHHHHHHHHHTCSS----CCHHHHHHHHHHHHHHHTTCHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHhCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHhcC----CCHHHHHHHHHHHHHHHhcCHHHHHHHHh
Confidence              22334444444421       112 23356678888888886520    14578889999999998865555444444


Q NP_000290.2     682 S--------SMLNNIINLCRSS-ASPKAAEAARLLLSDMWSS-KELQGVL  721 (747)
Q Consensus       682 ~--------giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~~~-~~~~~~~  721 (747)
                      .        +.+..|+.++... .+..++..++.+|.+++.. .+.+..+
T Consensus       354 ~~~~~~~~~~~l~~Ll~~l~~~~~~~~~r~~al~~L~~~~~~~~~~~~~l  403 (651)
T 3GRL_A          354 VNAPSNPPRPAIVVLLMSMVNERQPFVLRCAVLYCFQCFLYKNQKGQGEI  403 (651)
T ss_dssp             CEESSSSCEEHHHHHHHHHTCTTSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             CCCCCCCCchHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHhcCHHHHHHH
Confidence            2        2355666665432 1567888999999666653 3334333


No 176
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=96.31  E-value=1.5e-05  Score=72.85  Aligned_cols=113  Identities=18%  Similarity=0.215  Sum_probs=69.5  Template_Neff=12.300

Q NP_000290.2     246 TIPKAVQYLS-SQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP---------------NQNVQQAAAG  309 (747)
Q Consensus       246 iL~~Ll~lL~-ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~---------------d~eVr~~AL~  309 (747)
                      +++.++.++. ..+..++..++.++.+++... .....+...+++..+..++...               +..++..++.
T Consensus        95 ~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~-~~~~~~~~~~~~~~l~~ll~~~~~~~~~~~~~~~~~~~~~~~~~a~~  173 (233)
T 3TT9_A           95 GVPRLLQVLKQTRDLETKKQITGLLWNLSSND-KLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTG  173 (233)
T ss_dssp             HHHHHHHHHHHCCCHHHHHHHHHHHHHHHTSG-GGHHHHHHHHHHHHCCCCCHHHHCCCGGGCCCCCTTCCHHHHHHHHH
T ss_pred             cHHHHHHHHhhCCCHHHHHHHHHHHHHHccCH-HHHHHhhhhcHHHHHHHHHhhccCCCCCCCCcccCCCcHHHHHHHHH
Confidence            4555666665 456778888999999987633 2233333344555555554322               4567778888


Q NP_000290.2     310 ALRNLVFRSTTNKLETRRQNG-IREAVSLLRRTG------NAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       310 aLs~La~~~~~~~~~ll~~~I-L~~Ll~lL~ss~------d~eVr~~AL~aLsnLas~  360 (747)
                      ++.+++...+.....+...+. ++.+..++. ..      ++.++..++.+|.+++..
T Consensus       174 ~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~~~~L~~l~~~  230 (233)
T 3TT9_A          174 CLRNMSSAGADGRKAMRRCDGLIDSLVHYVR-GTIADYQPDDKATENCVCILHNLSYQ  230 (233)
T ss_dssp             HHHHHTTSCHHHHHHHHTSTTHHHHHHHHHH-HHHHTTCTTCHHHHHHHHHHHHHCCC
T ss_pred             HHHHHHhcCHHHHHHHHHcccHHHHHHHHHH-cccccCCCChHHHHHHHHHHHHhhhc
Confidence            888887643333333433344 777777775 33      466777788888777653


No 177
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=96.29  E-value=1.5e-05  Score=79.23  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=78.1  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       273 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  352 (466)
T 5D5K_C          273 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  352 (466)
T ss_dssp             GGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTCHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hhHhHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4555666666667788888999998887654433333444467777888887777788889999998887642 222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       353 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  386 (466)
T 5D5K_C          353 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  386 (466)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCcHHHHHHHhh-cCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 178
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=96.28  E-value=1.6e-05  Score=79.14  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=78.0  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       273 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  352 (466)
T 4UAF_B          273 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  352 (466)
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4555666666667788888999999887654433333444467777888887777788889999998887642 222222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       353 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~  386 (466)
T 4UAF_B          353 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  386 (466)
T ss_pred             HHhCCcHHHHHHHhh-cCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 179
>2JDQ_A IMPORTIN ALPHA-1 SUBUNIT, POLYMERASE BASIC; TRANSPORT, PB2 SUBUNIT, NUCLEAR PROTEIN; 2.2A {HOMO SAPIENS}
Probab=96.23  E-value=1.8e-05  Score=78.41  Aligned_cols=134  Identities=18%  Similarity=0.203  Sum_probs=87.8  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++.........+...++++.+...+.+.++.++..++.++..++..........
T Consensus       235 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  314 (450)
T 2JDQ_A          235 VCRRLVELLMHNDYKVVSPALRAVGNIVTGDDIQTQVILNCSALQSLLHLLSSPKESIKKEACWTISNITAGNRAQIQTV  314 (450)
T ss_dssp             THHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHTTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHHcCCCHHHHHHHHHHHHHHhhCChHHHHHHhhcchHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45566666666677888889999998887544333333334677778888877777888899999998876544333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST--DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~--~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++..  ......+.. ++++.|..++.
T Consensus       315 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~  371 (450)
T 2JDQ_A          315 IDANIFPALISILQ-TAEFRTRKEAAWAITNATSGGSAEQIKYLVELGCIKPLCDLLT  371 (450)
T ss_dssp             HHTTHHHHHHHHHH-HSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGG
T ss_pred             HhCCHHHHHHHHHh-cCCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHHHHHHHhh
Confidence            34457777777776 55677888888888888764  222222222 45555555554


No 180
>3IFQ_A plakoglobin, E-cadherin; armadillo repeat, Cardiomyopathy, Cell adhesion; HET: SO4; 2.8A {Homo sapiens}
Probab=96.23  E-value=1.8e-05  Score=80.55  Aligned_cols=367  Identities=18%  Similarity=0.234  Sum_probs=218.1  Template_Neff=13.100

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP-NQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~-d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.+.++.++..++.++..+....+.....+...++++.+...+... +..++..++.++..+..... ...
T Consensus       145 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~-~~~  223 (553)
T 3IFQ_A          145 DGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPS-NKP  223 (553)
T ss_dssp             TGGGGTGGGGGSSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHTTSTT-HHH
T ss_pred             CHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHHhcCCcHHHHHHHHHHHHHHhCCcc-hHH
Confidence            4556666667667778888899999988764443333333445677777777654 56778888888888876322 222


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCDGNSNMSREVVDPEVF  403 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~  403 (747)
                      .+...++++.+...+. ..++.++..++.++..++....... ...++++.+..++..                .++++.
T Consensus       224 ~~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~-~~~~~~~~l~~~l~~----------------~~~~~~  285 (553)
T 3IFQ_A          224 AIVEAGGMQALGKHLT-SNSPRLVQNCLWTLRNLSDVATKQE-GLESVLKILVNQLSV----------------DDVNVL  285 (553)
T ss_dssp             HHHHTTHHHHHHGGGG-SSCHHHHHHHHHHHHHHHTTCTTCS-CCHHHHHHHHTTTTC----------------CCHHHH
T ss_pred             HHHHCchHHHHHHHHh-cCCHHHHHHHHHHHHHhCChhHHHH-HHHHHHHHHHHHcCC----------------CCHHHH
Confidence            3333456777777776 5567788888888888876432211 112455555555532                133333


Q NP_000290.2     404 FNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAASRCDDKSVENCMCVLHNLS  483 (747)
Q Consensus       404 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  483 (747)
                      ..+..++..-..      ..+              ...+.+. -.+.++.++..+..    ..-+..-.+.+..+|.++.
T Consensus       286 ~~a~~~l~~l~~------~~~--------------~~~~~~~-~~~~~~~l~~~l~~----~~~~~~~~~~a~~~l~~l~  340 (553)
T 3IFQ_A          286 TCATGTLSNLTC------NNS--------------KNKTLVT-QNSGVEALIHAILR----AGDKDDITEPAVCALRHLT  340 (553)
T ss_dssp             HHHHHHHHHHTT------TCH--------------HHHHHHT-TTTHHHHHHHHHHH----HTTCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc------CCH--------------HHHHHHH-HccHHHHHHHHHHH----cCCChHhHHHHHHHHHHHh
Confidence            333333321100      000              0000000 01233333332211    0011222333344444443


Q NP_000290.2     484 YRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDA  563 (747)
Q Consensus       484 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~e  563 (747)
                      ...+..                                               ......+...++++.++.++....++.
T Consensus       341 ~~~~~~-----------------------------------------------~~~~~~~~~~~~~~~l~~~l~~~~~~~  373 (553)
T 3IFQ_A          341 SRHPEA-----------------------------------------------EMAQNSVRLNYGIPAIVKLLNQPNQWP  373 (553)
T ss_dssp             SSSTTH-----------------------------------------------HHHHHHHHTTTHHHHHHHGGGCTTCHH
T ss_pred             cCCChH-----------------------------------------------HHHHHHHHHcchHHHHHHHHcCCCChH
Confidence            211100                                               000112234566788888887322367


Q NP_000290.2     564 TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNS---------------------DVVRSGASLLSNM  622 (747)
Q Consensus       564 Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~---------------------eVr~~AL~aLsnL  622 (747)
                      ++..++.+|.+++....      ....+...++++.|..++.+.+.                     .++..++.+|.++
T Consensus       374 ~~~~a~~~l~~l~~~~~------~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l  447 (553)
T 3IFQ_A          374 LVKATIGLIRNLALCPA------NHAPLQEAAVIPRLVQLLVKAHQDAQRHVAAGTQQPYTDGVRMEEIVEGCTGALHIL  447 (553)
T ss_dssp             HHHHHHHHHHHHTTSGG------GHHHHHHTTHHHHHHHHHHHHHHHHHHHHHTTCCCTTCSSCCHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhcCcc------cHHHHHHccHHHHHHHHHHHcCcchhHHHhhcccCccccCCCHHHHHHHHHHHHHHH
Confidence            78889999999887532      12333456788888888876554                     7888899999998


Q NP_000290.2     623 SRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       623 a~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                      +..... ......++++.+..++.+      .++.++..++.+|.+++.. +.....+.+.++++.|..++.+. ++.++
T Consensus       448 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~-~~~v~  519 (553)
T 3IFQ_A          448 ARDPMNRMEIFRLNTIPLFVQLLYS------SVENIQRVAAGVLCELAQD-KEAADAIDAEGASAPLMELLHSR-NEGTA  519 (553)
T ss_dssp             TTSHHHHHHHHHTTCHHHHHHHTTC------SCHHHHHHHHHHHHHHTTS-HHHHHHHHHTTTHHHHHHHTTCS-SHHHH
T ss_pred             hcChhhHHHHHHcCChHHHHHHHhC------CCHHHHHHHHHHHHHHHcC-HHHHHHHHHCCcHHHHHHHHhCC-CHHHH
Confidence            875333 233445677888888775      3678899999999999875 44555555667888898888877 78899


Q NP_000290.2     702 EAARLLLSDMWSSKE  716 (747)
Q Consensus       702 ~aAL~aLsnL~~~~~  716 (747)
                      ..++.+|.+++...+
T Consensus       520 ~~a~~~l~~l~~~~~  534 (553)
T 3IFQ_A          520 TYAAAVLFRISEDKN  534 (553)
T ss_dssp             HHHHHHHHHTTSTTC
T ss_pred             HHHHHHHHHHHcccC
Confidence            999999999996543


No 181
>4BQK_A IMPORTIN SUBUNIT ALPHA-1A, T-DNA BORDER; TRANSPORT PROTEIN, HYDROLASE, NUCLEAR LOCALIZATION; HET: PEG; 1.997A {ORYZA SATIVA}
Probab=96.23  E-value=1.9e-05  Score=78.53  Aligned_cols=116  Identities=19%  Similarity=0.202  Sum_probs=77.5  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++..+....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus       172 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  251 (456)
T 4BQK_A          172 PALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQC  251 (456)
T ss_dssp             THHHHHHHHTTCCCHHHHHHHHHHHHHHTSSSHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            34556666666677788888999998887654433333334466777777777777788888999998887654333233


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      +...++++.+...+....++.++..++.++..++..
T Consensus       252 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~  287 (456)
T 4BQK_A          252 IIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAG  287 (456)
T ss_dssp             HHTTTHHHHHHHHHHSCCCHHHHHHHHHHHHHHHTS
T ss_pred             HHHCChHHHHHHHHHcCCCHHHHHHHHHHHHHHhcC
Confidence            333456677777775222566777888888887754


No 182
>4U5L_A deltaIBB-importin-alpha1; TPX2, inhibitor, TRANSPORT PROTEIN; HET: 3D6; 2.53A {Mus musculus}
Probab=96.17  E-value=2.2e-05  Score=76.74  Aligned_cols=115  Identities=21%  Similarity=0.205  Sum_probs=78.3  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.++.++..++.++..++...+.....
T Consensus       180 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  259 (426)
T 4U5L_A          180 QILPTLVRLLHHNDPEVLADSCWAISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGTDEQTQK  259 (426)
T ss_dssp             HHHHHHHHHTTSSCHHHHHHHHHHHHHHTSSCHHHHHHHHTTTCHHHHHHHHTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             HHHHHHHHHHhCCCHHHHHHHHHHHHHHhhCCcHHHHHHhhcChHHHHHHHhcCCCccHHHHHHHHHHHHhcCCHHHHHH
Confidence            45556666666677788888999998887654433333344457777888887777788889999998888654333333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      +...++++.+...+. +.++.++..++.++..++..
T Consensus       260 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~  294 (426)
T 4U5L_A          260 VIDAGALAVFPSLLT-NPKTNIQKEATWTMSNITAG  294 (426)
T ss_dssp             HHHTTGGGGHHHHTT-CSSHHHHHHHHHHHHHHTTS
T ss_pred             HhccchHHHHHHHhc-CCChHHHHHHHHHHHHHhcC
Confidence            334456677777775 45667777777777777653


No 183
>4BPL_A IMPORTIN SUBUNIT ALPHA-1A, NUCLEOPLASMIN NLS; TRANSPORT PROTEIN, NUCLEAR IMPORT, NUCLEAR; 2.3A {ORYZA SATIVA}
Probab=96.16  E-value=2.3e-05  Score=77.77  Aligned_cols=135  Identities=18%  Similarity=0.197  Sum_probs=84.9  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.+..++..++.++..+....+.....+...++++.+...+.+.+..++..++.++..++.........
T Consensus       170 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  249 (454)
T 4BPL_A          170 PALPALARLIHSNDEEVLTDACWALSYLSDGTNDKIQAVIEAGVCPRLVELLLHPSPSVLIPALRTVGNIVTGDDAQTQC  249 (454)
T ss_dssp             THHHHHHHHTTCCCHHHHHHHHHHHHHHTSSCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             HHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCChHHHHHHHHCCcHHHHHHHhhCCChHHHHHHHHHHHHHhcCCHHHHHH
Confidence            34556666666677788888999998887654433333334456777777777777788888999998887654333233


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRV  379 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL  379 (747)
                      +...++++.+...+....++.++..++.++..++..... ...+.. ++++.|..++
T Consensus       250 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l  306 (454)
T 4BPL_A          250 IIDHQALPCLLSLLTQNLKKSIKKEACWTISNITAGNKDQIQAVINAGIIGPLVNLL  306 (454)
T ss_dssp             HHTTTHHHHHHHHHHSSCCHHHHHHHHHHHHHHHTSCHHHHHHHHHHTCHHHHHHHH
T ss_pred             HHHCChHHHHHHHHHhcCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCcHHHHHHHh
Confidence            333456677777775222567778888888887754321 112222 4555555544


No 184
>4MZ6_E Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, Importin; ARM repeat, protein transport, Importin; 1.88A {Mus musculus}
Probab=96.12  E-value=2.6e-05  Score=79.03  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=77.9  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       317 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  396 (509)
T 4MZ6_E          317 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  396 (509)
T ss_dssp             GGGGHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4455566666667788888999998887654433333444467777888887777788889999998887642 222223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       397 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~  430 (509)
T 4MZ6_E          397 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCCHHHHHHHHh-CCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 185
>5UMZ_B Importin subunit alpha-1, TNRC6A; mRNA decay, miRNA ARM repeat; HET: GOL; 1.9A {Mus musculus}
Probab=96.12  E-value=2.6e-05  Score=79.03  Aligned_cols=113  Identities=17%  Similarity=0.142  Sum_probs=77.9  Template_Neff=12.800

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS-TTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~-~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++... ......
T Consensus       317 ~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  396 (509)
T 5UMZ_B          317 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVY  396 (509)
T ss_dssp             GGGGHHHHTTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCCHHHHHH
Confidence            4455566666667788888999998887654433333444467777888887777788889999998887642 222223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       397 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~  430 (509)
T 5UMZ_B          397 LVHCGIIEPLMNLLS-AKDTKIIQVILDAISNIFQ  430 (509)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCCHHHHHHHHh-CCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988876


No 186
>4E4V_A Importin subunit alpha-2; armadillo repeat, karyopherin, importin, nuclear; HET: GOL, DTT; 2.5283A {Homo sapiens}
Probab=96.12  E-value=2.7e-05  Score=78.66  Aligned_cols=113  Identities=17%  Similarity=0.130  Sum_probs=78.1  Template_Neff=12.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRST-TNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~-~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++.... .....
T Consensus       292 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  371 (485)
T 4E4V_A          292 ALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVVNHGLVPFLVSVLSKADFKTQKEAVWAVTNYTSGGTVEQIVY  371 (485)
T ss_dssp             GGGGHHHHHTCSSHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHHHHHSCHHHHHHHHHHHHHHHHHSCHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHcCCCHHHHHHHHHCCHHHHHHHHHhcCCHHHHHHHHHHHHHHHhcCCHHHHHH
Confidence            45556666666677888889999998876544333334444677778888877777888889999988876422 22222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      +...++++.+...+. ..++.++..++.++..++.
T Consensus       372 ~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~  405 (485)
T 4E4V_A          372 LVHCGIIEPLMNLLT-AKDTKIILVILDAISNIFQ  405 (485)
T ss_dssp             HHHTTCHHHHHHGGG-CSCHHHHHHHHHHHHHHHH
T ss_pred             HHhCCcHHHHHHHhh-cCCHHHHHHHHHHHHHHHH
Confidence            333346777777776 5567788889999988886


No 187
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=96.07  E-value=3.4e-05  Score=85.21  Aligned_cols=176  Identities=12%  Similarity=0.192  Sum_probs=126.8  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSG--------------MSQLIGL-KEKGLPQIARLLQS  606 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~--------------~~~~lli-e~giI~~Ll~LL~s  606 (747)
                      ++..++++.|+.+|... .+..++..++.+|.+++...+.  ..              .....+. +.+.++.|+.++.+
T Consensus        56 ~v~~~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~  133 (651)
T 3GQ2_A           56 EVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEE--EEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEE  133 (651)
T ss_dssp             HHHHHHHHHHHHHHTTCTTCHHHHHHHHHHHHHHHCCSSS--CC----------CHHHHHHHHHHTSHHHHHTHHHHTTC
T ss_pred             HHHccHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCCh--HhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccC
Confidence            46778999999999731 3567788899999998864321  00              0012223 57888999999888


Q NP_000290.2     607 GNSDVVRSGASLLSNMSRHP--LLH-RVM-GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS  682 (747)
Q Consensus       607 ~d~eVr~~AL~aLsnLa~~~--e~~-~ll-~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~  682 (747)
                      .++.++..++++|.+++...  ... .++ ..++++.|+.+|.+      .+..++..++.+|.+++..+++....+...
T Consensus       134 ~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~------~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~  207 (651)
T 3GQ2_A          134 FDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLAD------SREVIRNDGVLLLQALTRSNGAIQKIVAFE  207 (651)
T ss_dssp             CCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHGGGGGC------SSHHHHHHHHHHHHHHHTTCHHHHHHHHHT
T ss_pred             CCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHhC
Confidence            88889999999999998773  222 233 45678889998876      367888999999999998555666666677


Q NP_000290.2     683 SMLNNIINLCRSSAS---PKAAEAARLLLSDMWSSK-ELQGVLRQQGF  726 (747)
Q Consensus       683 giL~~Ll~LL~s~~d---~eVr~aAL~aLsnL~~~~-~~~~~~~~~~~  726 (747)
                      ++++.|+.++.....   ..++..++.+|.+|+... ..+..++..|+
T Consensus       208 g~~~~L~~ll~~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~  255 (651)
T 3GQ2_A          208 NAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSY  255 (651)
T ss_dssp             THHHHHHHHHHHTTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTC
T ss_pred             ChHHHHHHHHHHhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcCh
Confidence            889999998875411   257888999999988644 44555555554


No 188
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=96.07  E-value=3.4e-05  Score=85.21  Aligned_cols=176  Identities=12%  Similarity=0.192  Sum_probs=126.4  Template_Neff=10.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSG--------------MSQLIGL-KEKGLPQIARLLQS  606 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~--------------~~~~lli-e~giI~~Ll~LL~s  606 (747)
                      ++..++++.|+.+|... .+..++..++.+|.+++...+.  ..              .....+. +.+.++.|+.++.+
T Consensus        56 ~v~~~~l~~Li~~L~~~~~d~~~~~~al~~L~~l~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~Ll~ll~~  133 (651)
T 3GRL_A           56 EVGIQAMEHLIHVLQTDRSDSEIIGYALDTLYNIISNDEE--EEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEE  133 (651)
T ss_dssp             HCCCCCHHHHHHHHHSCTTCHHHHHHHHHHHHHHHCCC----------------CHHHHHHHHHHHSTHHHHHHHHHTTC
T ss_pred             HHHccHHHHHHHHHhcCCCCHHHHHHHHHHHHHHhCCCCh--HhhhhcccccchHHHHHHHHHHHhcCchHHHHHHHccC
Confidence            46778999999999731 3567788899999998864321  00              0012223 57888999999888


Q NP_000290.2     607 GNSDVVRSGASLLSNMSRHP--LLH-RVM-GNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSS  682 (747)
Q Consensus       607 ~d~eVr~~AL~aLsnLa~~~--e~~-~ll-~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~  682 (747)
                      .++.++..++++|.+++...  ... .++ ..++++.|+.+|.+      .+..++..++.+|.+++..+++....+...
T Consensus       134 ~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~------~~~~i~~~a~~~L~~l~~~~~~~~~~l~~~  207 (651)
T 3GRL_A          134 FDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLAD------SREVIRNDGVLLLQALTRSNGAIQKIVAFE  207 (651)
T ss_dssp             CCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGGC------SSHHHHHHHHHHHHHHHTTCHHHHHHHHHT
T ss_pred             CCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcC------CCHHHHHHHHHHHHHHhCCCHHHHHHHHhC
Confidence            88889999999999998773  222 233 45678889998876      367888999999999998555666666677


Q NP_000290.2     683 SMLNNIINLCRSSAS---PKAAEAARLLLSDMWSSK-ELQGVLRQQGF  726 (747)
Q Consensus       683 giL~~Ll~LL~s~~d---~eVr~aAL~aLsnL~~~~-~~~~~~~~~~~  726 (747)
                      ++++.|+.++.....   ..++..++.+|.+|+... ..+..++..|+
T Consensus       208 g~~~~L~~ll~~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~  255 (651)
T 3GRL_A          208 NAFERLLDIITEEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSY  255 (651)
T ss_dssp             THHHHHHHHHHHHTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTC
T ss_pred             ChHHHHHHHHHHhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcCh
Confidence            889999998875411   257888999999988644 44555555554


No 189
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=96.03  E-value=3.4e-05  Score=69.70  Aligned_cols=112  Identities=26%  Similarity=0.317  Sum_probs=74.8  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       135 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  214 (247)
T 4V3Q_A          135 ALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAV  214 (247)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888899988876543333333344567777777777777888889999988886543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..+.
T Consensus       215 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  246 (247)
T 4V3Q_A          215 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ  246 (247)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHT
T ss_pred             HHcCHHHHHHHHHh-CChHHHHHHHHHHHHHHc
Confidence            33456677777775 456677777777776653


No 190
>4TNM_A Importin-alpha3 / MOS6; armadillo repeat; 2.9A {Arabidopsis thaliana}
Probab=96.03  E-value=3.5e-05  Score=79.51  Aligned_cols=136  Identities=16%  Similarity=0.178  Sum_probs=85.8  Template_Neff=12.300

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..++.........+...++++.+...+.+.++.++..++.++..++.........
T Consensus       245 ~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  324 (531)
T 4TNM_A          245 PALPVLERLVQSMDEEVLTDACWALSYLSDNSNDKIQAVIEAGVVPRLIQLLGHSSPSVLIPALRTIGNIVTGDDLQTQM  324 (531)
T ss_pred             chHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCChHHHHHHHHhCCCHHHHHHHHHHHHHHHCCCHHHHHH
Confidence            34555666666667778888889988887654433333344467777778787777788888999998887654333223


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~  380 (747)
                      ....++++.+..++....++.++..++.++..++... .....+.. ++++.|..++.
T Consensus       325 ~~~~~~~~~l~~~l~~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  382 (531)
T 4TNM_A          325 VLDQQALPCLLNLLKNNYKKSIKKEACWTISNITAGNADQIQAVIDAGIIQSLVWVLQ  382 (531)
T ss_pred             HHHCCcHHHHHHHhcCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCcHHHHHHHhc
Confidence            3333566777777752235677888888888887643 22222222 45555555553


No 191
>4GMO_A Putative uncharacterized protein; ARM, HEAT, solenoid, nuclear transport; 2.1A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=95.93  E-value=5.4e-05  Score=85.22  Aligned_cols=94  Identities=14%  Similarity=0.083  Sum_probs=69.0  Template_Neff=8.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLV-DLLRSPNQNVQQAAAGALRNLVFRS-TTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll-~lL~s~d~eVr~~AL~aLs~La~~~-~~~~  322 (747)
                      ..+..|+..|.+.++.++..++.+|.+++.. +.....+...++++.|+ .++.+.+..++..++.+|.+++... ....
T Consensus        34 ~~i~~Li~~L~S~~~~~r~~A~~aL~~L~~d-~~~r~~l~~~g~i~~Li~~LL~d~~~~v~~~A~~aLrNLs~~~~~~~~  112 (684)
T 4GMO_A           34 DKILPVLKDLKSPDAKSRTTAAGAIANIVQD-AKCRKLLLREQVVHIVLTETLTDNNIDSRAAGWEILKVLAQEEEADFC  112 (684)
T ss_dssp             CCCHHHHHHHSSSCCSHHHHHHHHHHHHTTS-HHHHHHHHHTTHHHHCCCCCTTCSCHHHHHHHHHHHHHHHHHSCHHHH
T ss_pred             CChHHHHHHcCCCCHHHHHHHHHHHHHHhcC-HHHHHHHHHCChHHHHHHHHccCCCHHHHHHHHHHHHHHhccCChHHH
Confidence            4566778888888888999999999998763 44555566678888888 8888878889999999999998652 2333


Q NP_000290.2     323 LETRRQNGIREAVSLLR  339 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~  339 (747)
                      ..+...+++..|..++.
T Consensus       113 ~~l~~~g~l~~L~~lL~  129 (684)
T 4GMO_A          113 VHLYRLDVLTAIEHAAK  129 (684)
T ss_dssp             HHHHHTTHHHHHHHHHH
T ss_pred             HHHHHCChHHHHHHHHH
Confidence            34444566676666664


No 192
>4PLS_B Arm00010; PEPTIDE BINDING PROTEIN, designed armadillo; HET: CA; 2.35A {synthetic construct}
Probab=95.89  E-value=4.9e-05  Score=69.42  Aligned_cols=134  Identities=25%  Similarity=0.295  Sum_probs=87.2  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++..........
T Consensus        86 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  165 (281)
T 4PLS_B           86 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAV  165 (281)
T ss_dssp             CHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHcCCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666677788888888888876543333333344677777777777777888899999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       166 ~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  221 (281)
T 4PLS_B          166 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLS  221 (281)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCcHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHcc
Confidence            33456677777776 5567788888888888876422 2222222 56666666664


No 193
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=95.88  E-value=5e-05  Score=65.80  Aligned_cols=112  Identities=26%  Similarity=0.298  Sum_probs=74.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        89 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  168 (202)
T 5MFO_F           89 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  168 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcChHHHHHHH
Confidence            45556666666677788888999988876543333333344677777777777777888889999988886543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  200 (202)
T 5MFO_F          169 KEAGAEPALEQLQS-SPNEKIQKEAQEALEKIQ  200 (202)
T ss_dssp             HHTTHHHHHHTTTT-CSSHHHHHHHHHHHHHHH
T ss_pred             HHCCHHHHHHHHHc-CCCHHHHHHHHHHHHHHH
Confidence            33456666777775 446677777777776654


No 194
>2RU4_A Armadillo Repeat Protein, N-terminal fragment; solenoid repeat, Armadillo repeat motif; NMR {synthetic construct}
Probab=95.88  E-value=5.2e-05  Score=59.81  Aligned_cols=110  Identities=25%  Similarity=0.264  Sum_probs=70.0  Template_Neff=12.800

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRR  327 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~  327 (747)
                      +.+...+...+..++..++.++..++.........+...+.++.+...+.+.++.++..++.++.+++.........+..
T Consensus         4 ~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~   83 (115)
T 2RU4_A            4 PQMTQQLNSDDMQEQLSATRKFSQILSDGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVID   83 (115)
T ss_dssp             CCCCCCCCCCCCCCCSCCCCCCCCCCCSCTTHHHHHCCSSSHHHHHHGGGSSCHHHHHHHHHHHHHHHTTCHHHHHHHHT
T ss_pred             HHHHHhhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCchHHHHHHH
Confidence            34455555556677888888888887654333333444456777777777667778888888888887554333333333


Q NP_000290.2     328 QNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       328 ~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .+.++.+...+. ..++.++..++.++.+++
T Consensus        84 ~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~  113 (115)
T 2RU4_A           84 AGALPALVQLLS-SPNEQILQEALWALSNIA  113 (115)
T ss_dssp             TTHHHHHHHGGG-SSCHHHHHHHHHHHHHHH
T ss_pred             CCcHHHHHHHhc-CCCHHHHHHHHHHHHHHh
Confidence            456666666665 445667777777776654


No 195
>5AEI_B DESIGNED ARMADILLO REPEAT PROTEIN YIIIM5AII; DE NOVO PROTEIN, PROTEIN-PEPTIDE COMPLEX; HET: CA, ACT; 1.83A {SYNTHETIC CONSTRUCT}
Probab=95.87  E-value=5.1e-05  Score=69.48  Aligned_cols=114  Identities=26%  Similarity=0.296  Sum_probs=74.7  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++..+..........+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (286)
T 5AEI_B           47 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  126 (286)
T ss_dssp             CHHHHHHGGGCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHHTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             HHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHcChHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHH
Confidence            45556666666677888889999988876544333333344567777777777777888889999988876433332233


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...++++.+...+. ..++.++..++.++..++..
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  160 (286)
T 5AEI_B          127 IDAGALPALVQLLS-SPNEQILQEALWALSNIASG  160 (286)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTS
T ss_pred             HhCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHcC
Confidence            33446666666665 44566777777777776653


No 196
>5MFD_C YIIIM''6AII, Capsid decoration protein,pD_(KR)5; Designed armadillo repeat protein, peptide; HET: CA; 2.3A {synthetic construct}
Probab=95.87  E-value=5.1e-05  Score=70.81  Aligned_cols=157  Identities=20%  Similarity=0.303  Sum_probs=116.5  Template_Neff=13.300

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      +.++++.+..++. +.++.++..++.+|.+++.....     ....+...++++.+..++.+.++.++..++.+|.+++.
T Consensus       128 ~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~  201 (328)
T 5MFD_C          128 DAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIAS  201 (328)
T ss_dssp             HTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHTTSCHH-----HHHHHHHTTHHHHHHHGGGCSCHHHHHHHHHHHHHHHT
T ss_pred             HCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHc
Confidence            4456777888887 46777888899999998864332     22333456788888888888888899999999999987


Q NP_000290.2     625 H-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAE  702 (747)
Q Consensus       625 ~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~  702 (747)
                      . ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. ++.++.
T Consensus       202 ~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~  274 (328)
T 5MFD_C          202 GGNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSP-NEQILQ  274 (328)
T ss_dssp             SCHHHHHHHHHTTCHHHHHHGGGC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGCS-CHHHHH
T ss_pred             CCHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCChHHHHHHHhcCC-CHHHHH
Confidence            6 222 233445677888888766      3677889999999999865555545555566788888888766 788899


Q NP_000290.2     703 AARLLLSDMWSS  714 (747)
Q Consensus       703 aAL~aLsnL~~~  714 (747)
                      .++.+|.+++..
T Consensus       275 ~a~~~l~~l~~~  286 (328)
T 5MFD_C          275 EALWTLGNIASG  286 (328)
T ss_dssp             HHHHHHHHHHTS
T ss_pred             HHHHHHHHHhCC
Confidence            999999999865


No 197
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=95.87  E-value=5.2e-05  Score=65.68  Aligned_cols=112  Identities=26%  Similarity=0.298  Sum_probs=74.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        89 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  168 (202)
T 5MFO_E           89 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAV  168 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHhcCHHHHHHHH
Confidence            45556666666667788888899988876543333333344677777777777777888889999988886543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       169 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  200 (202)
T 5MFO_E          169 KEAGAEPALEQLQS-SPNEKIQKEAQEALEKIQ  200 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHC
T ss_pred             HHCCHHHHHHHHHc-CCCHHHHHHHHHHHHHHH
Confidence            33456666777775 446677777777776654


No 198
>5D5K_C Importin subunit alpha-1, Poly [ADP-ribose]; PARP-2 NLS, PARP-2, poly(ADP-ribose)polymerase-2, Importin; 1.9A {Mus musculus}
Probab=95.85  E-value=5.5e-05  Score=74.91  Aligned_cols=158  Identities=19%  Similarity=0.271  Sum_probs=114.4  Template_Neff=13.100

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDA-----TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~e-----Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      .+.++++.++.++.. .+..     ++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+
T Consensus       138 ~~~~~~~~l~~~l~~-~~~~~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~  211 (466)
T 5D5K_C          138 IKHGAIDPLLALLAV-PDLSTLACGYLRNLTWTLSNLCRNKNP-----APPLDAVEQILPTLVRLLHHNDPEVLADSCWA  211 (466)
T ss_dssp             HHTTCHHHHHHTTCS-SCGGGSCHHHHHHHHHHHHHHSCCCSS-----CCCHHHHHHHHHHHHHHTTSSCHHHHHHHHHH
T ss_pred             HHCCcHHHHHHHhhC-CCcccccHHHHHHHHHHHHHHHcCCCC-----CCChHHHHHHHHHHHHHHcCCCHHHHHHHHHH
Confidence            355667777777763 3333     677888888888765322     11121225678888888888888899999999


Q NP_000290.2     619 LSNMSRHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      |.+++.... . ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. 
T Consensus       212 l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  284 (466)
T 5D5K_C          212 ISYLTDGPNERIEMVVKKGVVPQLVKLLGA------TELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNP-  284 (466)
T ss_dssp             HHHHTSSCHHHHHHHHTTTCHHHHHHHHTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTGGGGHHHHTTCS-
T ss_pred             HHHHhcCCchHHHHHHHCChHHHHHHHhcC------CCchHHHHHHHHHHHHhcCCHHHHHHHHccChhHhHHHHhhCC-
Confidence            999987632 2 233455677888888876      3678889999999999876455555566667888888888766 


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.+|.+++..
T Consensus       285 ~~~v~~~a~~~l~~l~~~  302 (466)
T 5D5K_C          285 KTNIQKEATWTMSNITAG  302 (466)
T ss_dssp             SHHHHHHHHHHHHHHTTS
T ss_pred             CHHHHHHHHHHHHHHHcC
Confidence            788899999999998875


No 199
>1XQS_B HSPBP1 protein, Heat shock 70; armadillo repeat, superhelical twist, CHAPERONE; HET: AMP; 2.9A {Homo sapiens} SCOP: a.118.1.21
Probab=95.84  E-value=5.9e-05  Score=71.37  Aligned_cols=116  Identities=18%  Similarity=0.237  Sum_probs=80.5  Template_Neff=11.900

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+..++... +..++..++.++.+++.........+...+.++.+..++...+..++..++.++.+++.........
T Consensus       109 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~  188 (280)
T 1XQS_B          109 ALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEHKGT  188 (280)
T ss_dssp             HHHHHHHHHHSCSCHHHHHHHHHHHHHTTSSCHHHHHHHHTTTHHHHHHHHHTSSCHHHHHHHHHHHHHHHHHCGGGHHH
T ss_pred             HHHHHHHHhccCCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            455566666654 6778888999999988654433334444567777888777667778888999999888654423333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...++++.+..++. ..++.++..++.++.+++....
T Consensus       189 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~  225 (280)
T 1XQS_B          189 LCSMGMVQQLVALVR-TEHSPFHEHVLGALCSLVTDFP  225 (280)
T ss_dssp             HHTTTHHHHHHHHHT-SSCCTTHHHHHHHTTTSSTTCH
T ss_pred             HHhCCHHHHHHHHHc-CCCcHHHHHHHHHHHHHHhcCH
Confidence            444467777777776 5567788888999998887543


No 200
>4UAF_B Importin alpha 1 import receptor; importin karyopherin complex NLS, PROTEIN; HET: PO4; 1.698A {Mus musculus}
Probab=95.82  E-value=5.9e-05  Score=74.70  Aligned_cols=158  Identities=19%  Similarity=0.271  Sum_probs=114.6  Template_Neff=13.100

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDA-----TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~e-----Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      .+.++++.++.++.. .+..     ++..++.+|.+++.....     ........++++.+..++.+.++.++..++.+
T Consensus       138 ~~~~~~~~l~~~l~~-~~~~~~~~~~~~~~~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~  211 (466)
T 4UAF_B          138 IKHGAIDPLLALLAV-PDLSTLACGYLRNLTWTLSNLCRNKNP-----APPLDAVEQILPTLVRLLHHNDPEVLADSCWA  211 (466)
T ss_pred             HHCCcHHHHHHHhhC-CCcccccHHHHHHHHHHHHHHHcCCCC-----CCChhHHHHHHHHHHHHHcCCCHHHHHHHHHH
Confidence            355667777777763 3333     677888888888865332     11121225678888888888888999999999


Q NP_000290.2     619 LSNMSRHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      |.+++.... . ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+...++++.+..++.+. 
T Consensus       212 l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  284 (466)
T 4UAF_B          212 ISYLTDGPNERIEMVVKKGVVPQLVKLLGA------TELPIVTPALRAIGNIVTGTDEQTQKVIDAGALAVFPSLLTNP-  284 (466)
T ss_pred             HHHHhcCCcHHHHHHHHCChHHHHHHHhcC------CChhHHHHHHHHHHHHhcCCHHHHHHHhccCHHHHHHHHhcCC-
Confidence            999987632 2 233455678888888876      3678889999999999876455555566667888888888766 


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.+|.+++..
T Consensus       285 ~~~v~~~a~~~l~~l~~~  302 (466)
T 4UAF_B          285 KTNIQKEATWTMSNITAG  302 (466)
T ss_pred             CHHHHHHHHHHHHHHhcC
Confidence            788899999999999875


No 201
>1XQR_A HspBP1 protein; armadillo repeat, superhelical twist, CHAPERONE; HET: MSE; 2.1A {Homo sapiens} SCOP: a.118.1.21
Probab=95.82  E-value=6.4e-05  Score=72.71  Aligned_cols=116  Identities=18%  Similarity=0.237  Sum_probs=81.0  Template_Neff=11.300

Q NP_000290.2     246 TIPKAVQYLSSQ-DEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ss-d~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+..++... ++.++..++.++.+++.........+...++++.+...+...+..++..++.++.+++.........
T Consensus       125 ~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~  204 (296)
T 1XQR_A          125 ALRKLLRLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQQQVQKLKVKSAFLLQNLLVGHPEHKGT  204 (296)
T ss_dssp             HHHHHHHHHHHCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHCGGGHHH
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHH
Confidence            455566666654 6778889999999998754433334444567777887777667788888999999888754433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      +...++++.+..++. ..++.++..++.+|.+++....
T Consensus       205 ~~~~~~i~~L~~ll~-~~~~~~~~~a~~~L~~l~~~~~  241 (296)
T 1XQR_A          205 LCSMGMVQQLVALVR-TEHSPFHEHVLGALCSLVTDFP  241 (296)
T ss_dssp             HHHTTHHHHHHHHHT-SCCSTHHHHHHHHHHHHHTTCH
T ss_pred             HHhCCHHHHHHHHHc-CCChHHHHHHHHHHHHHHhcCH
Confidence            444567777777776 4566788888899988887543


No 202
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=95.81  E-value=6.2e-05  Score=78.24  Aligned_cols=151  Identities=10%  Similarity=0.021  Sum_probs=91.7  Template_Neff=12.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ---SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~---s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|+.++. +.+..++..++.++..+....+.          ....+++.+...+.   ..+..++ .++++|+.+.
T Consensus       414 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~~~r-~a~~~l~~~~  481 (585)
T 6CRI_R          414 WHIDTIMRVLT-TAGSYVRDDAVPNLIQLITNSVE----------MHAYTVQRLYKAILGDYSQQPLVQ-VAAWCIGEYG  481 (585)
T ss_pred             HHHHHHHHHHH-HhccccCccHHHHHHHHHhcCch----------HHHHHHHHHHHHHHCCCCCHHHHH-HHHHHHHHHH
Confidence            35566666666 35566777777777777653211          11234555666653   3344556 7888888877


Q NP_000290.2     624 RHPLLH--------RVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       624 ~~~e~~--------~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~  693 (747)
                      ......        ......+++.|..++  .+      .+..++..++.+|..+....+.     ....++..+..++.
T Consensus       482 ~~~~~~~~~~~~~~~~~~~~~~~~L~~~l~~~~------~~~~vr~~a~~al~~l~~~~~~-----~~~~~~~~l~~~~~  550 (585)
T 6CRI_R          482 DLLVSGQCEEEEPIQVTEDEVLDILESVLISNM------STSVTRGYALTAIMKLSTRFTC-----TVNRIKKVVSIYGS  550 (585)
T ss_pred             HHhcCCCCCCCCCCCCCHHHHHHHHHHHhcccC------CCHHHHHHHHHHHHHHHhcCCc-----hHHHHHHHHHHHcc
Confidence            642110        111234566666666  33      3567888999999998875332     22234555666666


Q NP_000290.2     694 SSASPKAAEAARLLLSDMWSSKELQGVL  721 (747)
Q Consensus       694 s~~d~eVr~aAL~aLsnL~~~~~~~~~~  721 (747)
                      +. ++.++..++.++..+..+......+
T Consensus       551 ~~-~~~vr~~a~~~l~~l~~~~~~~~~l  577 (585)
T 6CRI_R          551 SI-DVELQQRAVEYNALFKKYDHMRSAL  577 (585)
T ss_pred             CC-CHHHHHHHHHHHHHhhhHHHHHHHH
Confidence            65 7889999999999988765544443


No 203
>6SA8_A ring-like DARPin-Armadillo fusion H83_D01, LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG-LYS-ARG; protein fusion, DARPin, Armadillo, shared; 2.4A {synthetic construct}
Probab=95.78  E-value=6.8e-05  Score=80.44  Aligned_cols=136  Identities=26%  Similarity=0.298  Sum_probs=92.6  Template_Neff=11.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.+|.+++...+.....+...++++.+..++.+.++.++..++.++..++.........
T Consensus       262 ~~~~~l~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~L~~~l~~~~~~v~~~a~~~L~~l~~~~~~~~~~  341 (671)
T 6SA8_A          262 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQA  341 (671)
T ss_dssp             TCHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             CHHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCcHHHHHHHHhChHHHHHHHhcCCcHHHHHHHHHHHHHHhcCCcHHHHH
Confidence            34556666666677788889999999887654333334444567788888888777888889999999987654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      +...++++.+...+. ..++.++..++.++..++.. ......+.. ++++.|+.++..
T Consensus       342 ~~~~~~l~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~  399 (671)
T 6SA8_A          342 VIDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSS  399 (671)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHGGGC
T ss_pred             HHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCcHHHHHHHHcCcHHHHHHHhcC
Confidence            334456777777776 55677888899999998873 332333333 677777776653


No 204
>5WBJ_A Regulatory-associated protein of TOR 1,Eukaryotic; Raptor, TOS, PROTEIN BINDING; 3.0A {Arabidopsis thaliana}
Probab=95.77  E-value=8.1e-05  Score=89.51  Aligned_cols=168  Identities=12%  Similarity=0.072  Sum_probs=120.9  Template_Neff=8.700

Q NP_000290.2     541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASL  618 (747)
Q Consensus       541 ~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~a  618 (747)
                      ..+...|+++.++.+|. +..++++..++.++.+++..++.     .+..+.+.+++..|+.+|...  .+.++..++.+
T Consensus       500 ~~~~~~gi~p~ll~lL~-s~~~~lr~~a~~i~a~i~~~d~~-----~q~~l~~~~~l~~ll~~L~~~~~~~~~r~~a~~~  573 (1287)
T 5WBJ_A          500 DLALSVGIFPYVLKLLQ-TTTNELRQILVFIWTKILALDKS-----CQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFV  573 (1287)
T ss_dssp             HHHHHHTCHHHHHHGGG-CCCHHHHHHHHHHHHHHHHHCGG-----GHHHHHHTTCHHHHHHHHHCSSCCHHHHHHHHHH
T ss_pred             HHHHHCCcHHHHHHHHc-CCCHHHHHHHHHHHHHHHccCHH-----HHHHHHHcCCeeeEEEeecCCCCCHHHHHHHHHH
Confidence            33457789999999998 47788899999999999876443     344556677888899988743  35567788999


Q NP_000290.2     619 LSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTG-NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS  695 (747)
Q Consensus       619 LsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~-~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~  695 (747)
                      |+.++.. ... ..+...+++..+...|..... ....++.++..++.+|..|+...+.........+++..|+.+|.+.
T Consensus       574 Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~~~~lr~~a~~~L~~L~~~~~~~~~~~~~~~~~~~L~~lL~~~  653 (1287)
T 5WBJ_A          574 LAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQPEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEP  653 (1287)
T ss_dssp             HHHHHTTCHHHHHHHHHTTHHHHHHHHCC---------CHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHGGGGGCS
T ss_pred             HHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHhccHHHHHHHHHcCHHHHHHHHhcCC
Confidence            9999876 222 233444677777777761000 0003678899999999999877555555556667788899999877


Q NP_000290.2     696 ASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       696 ~d~eVr~aAL~aLsnL~~~~  715 (747)
                       ++.++.+++.+|+.++...
T Consensus       654 -~~~VRaaal~aL~~li~~~  672 (1287)
T 5WBJ_A          654 -QPEVRAAAVFALGTLLDIG  672 (1287)
T ss_dssp             -CHHHHHHHHHHHHHTCC--
T ss_pred             -CHHHHHHHHHHHHHHHhcC
Confidence             8899999999999998764


No 205
>5Z8H_A Adenomatous polyposis coli protein, Peptide; APC, inhibitor, PROTEIN BINDING-INHIBITOR complex; HET: PHQ, GOL; 1.79A {Homo sapiens}
Probab=95.74  E-value=7.4e-05  Score=71.65  Aligned_cols=115  Identities=17%  Similarity=0.172  Sum_probs=76.4  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQD----EKYQAIGAYYIQHTCF---QDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       246 iL~~Ll~lL~ssd----~eVr~sAL~aLsnLs~---~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      +++.+..++...+    ..++..++.++.++..   ........+...++++.+..++...++.++..++.++.+++...
T Consensus       210 ~~~~l~~~l~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~L~~l~~~~  289 (339)
T 5Z8H_A          210 ALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNCLQTLLQHLKSHSLTIVSNACGTLWNLSARN  289 (339)
T ss_pred             hHHHHHHHhcCCCCCCCHHHHHHHHHHHHHHHHhhccCHHHHHHHHHCCHHHHHHHHHhCCCHHHHHHHHHHHHHHhCCC
Confidence            4445555554332    5677778888887752   22223333334467777788787777788889999999988744


Q NP_000290.2     319 TTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD  361 (747)
Q Consensus       319 ~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~  361 (747)
                      +.....+...++++.+..++. ..++.++..++.++.+++...
T Consensus       290 ~~~~~~~~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~  331 (339)
T 5Z8H_A          290 PKDQEALWDMGAVSMLKNLIH-SKHKMIAMGSAAALRNLMANR  331 (339)
T ss_pred             HHHHHHHHHCCcHHHHHHHhh-CCCHHHHHHHHHHHHHHHcCC
Confidence            443344444567788888886 556778888999998888643


No 206
>5WBK_A Regulatory-associated protein of TOR 1,Ribosomal; Raptor, TOS, PROTEIN BINDING; 3.11A {Arabidopsis thaliana}
Probab=95.72  E-value=9.2e-05  Score=89.00  Aligned_cols=168  Identities=12%  Similarity=0.072  Sum_probs=120.7  Template_Neff=8.700

Q NP_000290.2     541 GWLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASL  618 (747)
Q Consensus       541 ~~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~a  618 (747)
                      ..+...|+++.|+++|. +..++++..++.++.+++..++.     .+..+.+.+++..|+.+|...  .+.++..++.+
T Consensus       500 ~~~l~~Gi~p~ll~lL~-s~~~~lr~~a~~i~a~i~~~d~~-----~q~~l~~~~~l~~ll~~L~~~~~~~~~r~~a~~~  573 (1287)
T 5WBK_A          500 DLALSVGIFPYVLKLLQ-TTTNELRQILVFIWTKILALDKS-----CQIDLVKDGGHTYFIRFLDSSGAFPEQRAMAAFV  573 (1287)
T ss_dssp             HHHHHHTCHHHHHHGGG-CCCHHHHHHHHHHHHHHHHHCGG-----GHHHHHHTTTHHHHHHHHHSSCCCHHHHHHHHHH
T ss_pred             HHHHHCCcHHHHHHHHc-CCCHHHHHHHHHHHHHHHccCHH-----HHHHHHHcCCeeeEEEeecCCCCCHHHHHHHHHH
Confidence            33457789999999998 46778899999999999876443     344456677888899988743  35567788899


Q NP_000290.2     619 LSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTG-NTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS  695 (747)
Q Consensus       619 LsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~-~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~  695 (747)
                      |+.++.. ... ..+...+++..+...|..... ....++.++..++.+|+.|+...+.........+++..|+.+|.+.
T Consensus       574 Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~~~~lr~~a~~~L~~L~~~~~~~~~~~~~~~~~~~L~~lL~~~  653 (1287)
T 5WBK_A          574 LAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQPEPLFLQWLCLCLGKLWEDFMEAQIMGREANAFEKLAPLLSEP  653 (1287)
T ss_dssp             HHHHHTTCHHHHHHHHHTTHHHHHHHHCC---------CHHHHHHHHHHHHHHHTTCHHHHHHHHTTTHHHHHGGGGGCS
T ss_pred             HHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHcccHHHHHHHHHCCHHHHHHHHhcCC
Confidence            9999876 222 233444677777777761000 0003678899999999999876555555556667788899999877


Q NP_000290.2     696 ASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       696 ~d~eVr~aAL~aLsnL~~~~  715 (747)
                       ++.+|.+++.+|+.++...
T Consensus       654 -~~~VRaaal~AL~~li~~~  672 (1287)
T 5WBK_A          654 -QPEVRAAAVFALGTLLDIG  672 (1287)
T ss_dssp             -CHHHHHHHHHHHHHHCC--
T ss_pred             -CHHHHHHHHHHHHHHHhcC
Confidence             8899999999999998764


No 207
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=95.69  E-value=8.4e-05  Score=73.16  Aligned_cols=135  Identities=25%  Similarity=0.260  Sum_probs=92.1  Template_Neff=12.400

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+..++.+.++.++..++.+|.+++.........+...++++.+..++...++.++..++.+|..++.........
T Consensus       241 ~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  320 (397)
T 6SA6_A          241 GALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQA  320 (397)
T ss_dssp             THHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHH
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHhcCcHHHHHHHHhCChHHHHHHHhcCCcHHHHHHHHHHHHHHhcCcHHHHHH
Confidence            34566666777777888889999999987654333333444467777888887777788888899998887654433333


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVI  380 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~  380 (747)
                      +...++++.+..++. ..++.++..++.++..++.. ......+.. ++++.|..++.
T Consensus       321 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  377 (397)
T 6SA6_A          321 VIDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGNEQKQAVKEAGALEKLEQLQS  377 (397)
T ss_dssp             HHHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHhcChHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHcCchHHHHHHHh
Confidence            444567777888776 55678888899999998874 333333333 67777777664


No 208
>2W3C_A GENERAL VESICULAR TRANSPORT FACTOR P115; MEMBRANE VESICLE TETHERING, ARMADILLO FOLD; HET: PEG; 2.22A {HOMO SAPIENS}
Probab=95.59  E-value=0.00012  Score=79.14  Aligned_cols=136  Identities=15%  Similarity=0.146  Sum_probs=91.0  Template_Neff=10.400

Q NP_000290.2     246 TIPKAVQYLSSQ--DEKYQAIGAYYIQHTCFQDES-----------------AKQQVY-QLGGICKLVDLLRSPNQNVQQ  305 (747)
Q Consensus       246 iL~~Ll~lL~ss--d~eVr~sAL~aLsnLs~~~~~-----------------~~~~li-~~~IL~~Ll~lL~s~d~eVr~  305 (747)
                      .++.++..+.+.  +..+...++.+|..++.....                 ....+. ..+.++.++.++.+.+..++.
T Consensus         9 ~l~~Li~~L~~~~~~~~~~~~al~~L~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~L~~ll~~~~~~v~~   88 (577)
T 2W3C_A            9 AMEHLIHVLQTDRSDSEIIGYALDTLYNIISNEEEEEVEENSTRQSEDLGSQFTEIFIKQQENVTLLLSLLEEFDFHVRW   88 (577)
T ss_dssp             TTHHHHHHHHHCTTCHHHHHHHHHHHHHHHHC------------------CHHHHHHHHSTHHHHHHHHHTTCCCHHHHH
T ss_pred             hHHHHHHHHhhCCCcHHHHHHHHHHHHHHhCCCchhhhhhccccccHHHHHHHHHHHHhcCchHHHHHHHccCCCHHHHH
Confidence            345566666543  456778888888888765431                 122233 456777788888777788899


Q NP_000290.2     306 AAAGALRNLVFRST-TNKLETR-RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTD-ELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       306 ~AL~aLs~La~~~~-~~~~~ll-~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~-~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      .++.+|..++...+ .....+. ..+.++.++.++. ..+..++..++.+|.+++... .....+.. ++++.|+.++..
T Consensus        89 ~a~~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~-~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~g~~~~L~~ll~~  167 (577)
T 2W3C_A           89 PGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLA-DSREVIRNDGVLLLQALTRSNGAIQKIVAFENAFERLLDIISE  167 (577)
T ss_dssp             HHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGG-CSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhchHHHHHHHHhCCChHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHcCCHHHHHHHHHHH
Confidence            99999999886543 2222333 2467888888886 556788999999999998743 33333333 889999988875


Q NP_000290.2     382 P  382 (747)
Q Consensus       382 ~  382 (747)
                      .
T Consensus       168 ~  168 (577)
T 2W3C_A          168 E  168 (577)
T ss_dssp             T
T ss_pred             h
Confidence            3


No 209
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=95.58  E-value=0.0001  Score=74.75  Aligned_cols=106  Identities=11%  Similarity=0.025  Sum_probs=69.8  Template_Neff=13.200

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.+..++..++.++..+....       ....+++.+...+.+.++.++..++.++..+.........
T Consensus        72 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~~~~  144 (570)
T 6CRI_I           72 IMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLVE  144 (570)
T ss_dssp             GTTHHHHHHHTSSSCHHHHHHHHHHHHHCCCTT-------TTTTSHHHHHHHHTCSSHHHHHHHHHHHHHHHHHCHHHHH
T ss_pred             HHHHHHHHHHcCCCCHHHHHHHHHHHccCChhH-------HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHhChhhhh
Confidence            344555666666677778888888887775321       1123556666667777788888899988888754332211


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ...+++.+...+. +.++.++..++.++..+...
T Consensus       145 ---~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~  177 (570)
T 6CRI_I          145 ---DQGFLDTLKDLIS-DSNPMVVANAVAALSEIAES  177 (570)
T ss_dssp             ---HHTHHHHHHHHHT-SSSHHHHHHHHHHHHHHHHH
T ss_pred             ---ccchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhh
Confidence               1345666677776 56778888899888888764


No 210
>1QBK_B STRUCTURE OF THE KARYOPHERIN BETA2-RAN; HEAT REPEATS, NUCLEAR TRANSPORT PROTEIN; HET: GNP; 3.0A {Homo sapiens} SCOP: a.118.1.1
Probab=95.57  E-value=0.00011  Score=79.31  Aligned_cols=157  Identities=12%  Similarity=0.081  Sum_probs=97.3  Template_Neff=13.200

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.+|..++...+.     ....+ -..+++.+...+.+.+..++..++.++..++...
T Consensus       667 ~~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  739 (890)
T 1QBK_B          667 NILTLMYQCMQ-DKMPEVRQSSFALLGDLTKACFQ-----HVKPC-IADFMPILGTNLNPEFISVCNNATWAIGEISIQM  739 (890)
T ss_pred             hHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHhHH-----hHHHH-HHHHHHHHHhhcCcccHHHHHHHHHHHHHHHHHc
Confidence            35566666666 36778888899999988764321     11111 1346667777777777889999999999988652


Q NP_000290.2     627 -LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 -e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                       .........+++.+...+.+.    ..+..++..++.+|+.++...+....... ..++..++..+....++.++..++
T Consensus       740 ~~~~~~~~~~i~~~l~~~l~~~----~~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~~~  814 (890)
T 1QBK_B          740 GIEMQPYIPMVLHQLVEIINRP----NTPKTLLENTAITIGRLGYVCPQEVAPML-QQFIRPWCTSLRNIRDNEEKDSAF  814 (890)
T ss_pred             CccccchHHHHHHHHHHHHcCC----CCCccHHHHHHHHHHHHHhhCHHhHHHHH-HHhHHHHHHHHhcCCChHHHHHHH
Confidence             211112234566677766541    01567888999999998875332211111 234555666555432567788888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..+....
T Consensus       815 ~~l~~l~~~~  824 (890)
T 1QBK_B          815 RGICTMISVN  824 (890)
T ss_pred             HHHHHHHhhC
Confidence            8888776543


No 211
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=95.56  E-value=0.00012  Score=77.66  Aligned_cols=151  Identities=10%  Similarity=0.027  Sum_probs=89.9  Template_Neff=12.000

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ---SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~---s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|+.++. +.++.++..++.+|..+....+.          ....+++.+...+.   ..+..++ .++++|+.+.
T Consensus       431 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~~~r-~a~~~l~~~~  498 (627)
T 4P6Z_G          431 WHIDTIMRVLT-TAGSYVRDDAVPNLIQLITNSVE----------MHAYTVQRLYKAILGDYSQQPLVQ-VAAWCIGEYG  498 (627)
T ss_dssp             HHHHHHHHHHH-HTGGGSCGGGHHHHHHHHHSCTT----------TTHHHHHHHHHHHHHCCCSHHHHH-HHHHHHHHTH
T ss_pred             HHHHHHHHHHH-hhccccCcchHHHHHHHHhcCch----------HHHHHHHHHHHHHHcCCCCHHHHH-HHHHHHHHHH
Confidence            35566666665 35566677777777776643211          01234455555553   2334555 7778887776


Q NP_000290.2     624 RHPLL-H-------RVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR  693 (747)
Q Consensus       624 ~~~e~-~-------~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~  693 (747)
                      ..... .       ......+++.|..++  .+      .++.++..++.+|..+....+.     ....++..|..++.
T Consensus       499 ~~~~~~~~~~~~~~~~~~~~~~~~L~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~-----~~~~~~~~l~~~~~  567 (627)
T 4P6Z_G          499 DLLVSGQCEEEEPIQVTEDEVLDILESVLISNM------STSVTRGYALTAIMKLSTRFTC-----TVNRIKKVVSIYGS  567 (627)
T ss_dssp             HHHHSCCCTTSCCCCCCSHHHHHHHHHHHHCTT------CCHHHHHHHHHHHHHHHHHCCS-----CHHHHHHHHHHGGG
T ss_pred             HHhccCCCCCCCCCCCCHHHHHHHHHHHHcccC------CCHHHHHHHHHHHHHHHhhccc-----hHHHHHHHHHHHcc
Confidence            54111 0       011124566666666  33      3567889999999998865332     22234566666666


Q NP_000290.2     694 SSASPKAAEAARLLLSDMWSSKELQGVL  721 (747)
Q Consensus       694 s~~d~eVr~aAL~aLsnL~~~~~~~~~~  721 (747)
                      +. +..++..++.++..+..+......|
T Consensus       568 ~~-~~~vr~~a~~~l~~l~~~~~~~~~l  594 (627)
T 4P6Z_G          568 SI-DVELQQRAVEYNALFKKYDHMRSAL  594 (627)
T ss_dssp             CS-CHHHHHHHHHHHHHHHHCTTHHHHH
T ss_pred             CC-CHHHHHHHHHHHHHhhhHHHHHHHH
Confidence            65 7889999999999988764444443


No 212
>5MFI_B YIII(Dq.V2)4CqI, (KR)4; Designed armadillo repeat protein, peptide; 1.45A {synthetic construct}
Probab=95.46  E-value=0.00014  Score=65.05  Aligned_cols=112  Identities=20%  Similarity=0.227  Sum_probs=75.6  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       131 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  210 (243)
T 5MFI_B          131 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  210 (243)
T ss_dssp             CHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666667788888889888876544333333444577778888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       211 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  242 (243)
T 5MFI_B          211 EEAGAEPALEKLQS-SPNEEVQKNAQAALEALN  242 (243)
T ss_dssp             HHTTHHHHHHHGGG-CSCHHHHHHHHHHHHHHC
T ss_pred             HHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHhc
Confidence            33456667777775 456677777777777654


No 213
>5MFJ_B YIII(Dq.V2)4CqI, (KR)5; Designed armadillo repeat protein, peptide; 1.53A {synthetic construct}
Probab=95.46  E-value=0.00014  Score=65.05  Aligned_cols=112  Identities=20%  Similarity=0.227  Sum_probs=75.6  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus       131 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  210 (243)
T 5MFJ_B          131 ALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKLIEAGALSPLVKLLDDASEEVIQEAVWAIANIASGNNEQIQKL  210 (243)
T ss_dssp             CHHHHHHTTTSSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTCHHHHHHGGGCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             cHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCcHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666666667788888889888876544333333444577778888877778888899999998886444333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       211 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  242 (243)
T 5MFJ_B          211 EEAGAEPALEKLQS-SPNEEVQKNAQAALEALN  242 (243)
T ss_dssp             HHTTHHHHHHHTSS-CSCHHHHHHHHHHHHHHC
T ss_pred             HHCCcHHHHHHHhc-CCCHHHHHHHHHHHHHhc
Confidence            33456667777775 456677777777777654


No 214
>5EWP_B Uncharacterized protein; translocation and attachment of rhoptries; 1.8A {Plasmodium falciparum Santa Lucia}
Probab=95.43  E-value=0.00015  Score=67.32  Aligned_cols=134  Identities=16%  Similarity=0.127  Sum_probs=89.1  Template_Neff=11.800

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+..++...+..++..++.++.+++.........+...+.++.++.++...+..++..++.++.+++.........+
T Consensus        87 ~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~~~~~~~  166 (252)
T 5EWP_B           87 GIAVFINLLKSHELDRVHAAVVALSFLSVDNVKNCICMFESGALPYLISGMKSNIDGMKAACAQTCRNIFVLDKKYKKEF  166 (252)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTCHHHHHHHTTCSCHHHHHHHHHHHHHHHTTCHHHHHHH
T ss_pred             cHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhhCCCHHHHHHHHHHHHHHHhcCHHHHHHH
Confidence            45556666666667788889999999887544444445555677888888877677888999999999876533333344


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNA-------EIQKQLTGLLWNLSSTDEL-----KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~-------eVr~~AL~aLsnLas~~~~-----~~~Lve-giLe~Lv~LL~  380 (747)
                      ...+.++.+..++. ....       .++..++.++..++.....     ...+.. ++++.|..++.
T Consensus       167 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~l~~~~~~~~L~~~l~  233 (252)
T 5EWP_B          167 LKLGGITQLVNLLE-LPSNYDDSQPLYTQLEAIYHLEDFILNDGDEIPEFLEAVKNSNSIKNLKTLQQ  233 (252)
T ss_dssp             HHTTHHHHHHHTTS-CCTTCCSCSCCHHHHHHHHHHHHHHEETTEECHHHHHHHHTTTHHHHHHHHTT
T ss_pred             HHCChHHHHHHHhc-CCCCCCCCchHHHHHHHHHHHHHHHhcCCCccHHHHHHHHhCChHHHHHHHhh
Confidence            44567777777775 3333       2777788888888764331     223333 66777777663


No 215
>4V3Q_A YIII_M4_AII; DE NOVO PROTEIN, PROTEIN ENGINEERING; HET: GOL, CA; 1.8A {SYNTHETIC CONSTRUCT}
Probab=95.36  E-value=0.00017  Score=64.82  Aligned_cols=134  Identities=25%  Similarity=0.303  Sum_probs=88.0  Template_Neff=12.900

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++..++...+.....+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        51 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  130 (247)
T 4V3Q_A           51 ALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGDEQIQAV  130 (247)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             cHHHHHHHhcCCCHHHHHHHHHHHHHHHcCcHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45556666766677888889999998876544333334445677788888877778888889999988875443333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE-LKEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~-~~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++.... ....+.. ++++.+..++.
T Consensus       131 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  186 (247)
T 4V3Q_A          131 IDAGALPALVQLLS-SPNEQILQEALWTLGNIASGGDEQIQAVIDAGALPALVQLLS  186 (247)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCCcHHHHHHHhc
Confidence            34466777777776 4566778888888888876432 2222222 55666665554


No 216
>3GQ2_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.18A {Bos taurus}
Probab=95.28  E-value=0.00022  Score=78.31  Aligned_cols=135  Identities=13%  Similarity=0.116  Sum_probs=92.0  Template_Neff=10.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ-QVY-QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~-~li-~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++.++.++...+..++..++.+|..++...+.... .+. ..+.++.++.++.+.+..++..++.+|..++........
T Consensus       123 ~i~~Ll~ll~~~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~~~~~i~~~a~~~L~~l~~~~~~~~~  202 (651)
T 3GQ2_A          123 NVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQK  202 (651)
T ss_dssp             HHHTHHHHTTCCCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHGGGGGCSSHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHH
Confidence            455566666666778889999999998865432221 222 345778888888877778889999999999874444434


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSSTDELKEE-LIA-DALPVLADRVII  381 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas~~~~~~~-Lve-giLe~Lv~LL~~  381 (747)
                      .+...+.++.++.++. ...    ..++..++.+|.+++........ +.+ ++++.|+.+|..
T Consensus       203 ~l~~~g~~~~L~~ll~-~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~i~~L~~lL~~  265 (651)
T 3GQ2_A          203 IVAFENAFERLLDIIT-EEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEV  265 (651)
T ss_dssp             HHHHTTHHHHHHHHHH-HTTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCGGGTGGGGCC
T ss_pred             HHHhCChHHHHHHHHH-HhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcChHHHHHHHHhc
Confidence            4445577888888876 322    25777888899998875433333 334 788888888864


No 217
>3GRL_A General vesicular transport factor p115; vesicle transport, membrane trafficking, membrane; 2.0A {Bos taurus}
Probab=95.28  E-value=0.00022  Score=78.31  Aligned_cols=135  Identities=13%  Similarity=0.116  Sum_probs=92.0  Template_Neff=10.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQ-QVY-QLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~-~li-~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++.++.++...+..++..++.+|..++...+.... .+. ..+.++.++.++.+.+..++..++.+|..++........
T Consensus       123 ~i~~Ll~ll~~~~~~~~~~al~~L~~l~~~~~~~~~~~i~~~~~~i~~Lv~lL~~~~~~i~~~a~~~L~~l~~~~~~~~~  202 (651)
T 3GRL_A          123 NVTLLLSLLEEFDFHVRWPGVKLLTSLLKQLGPQVQQIILVSPMGVSRLMDLLADSREVIRNDGVLLLQALTRSNGAIQK  202 (651)
T ss_dssp             HHHHHHHHTTCCCHHHHHHHHHHHHHHHHHSHHHHHHHHHHSTTHHHHHHGGGGCSSHHHHHHHHHHHHHHHTTCHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHHhccHHHHHHHHhCccHHHHHHHHhcCCCHHHHHHHHHHHHHHhCCCHHHHH
Confidence            455566666666778889999999998865432221 222 345778888888877778889999999999874444434


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGN----AEIQKQLTGLLWNLSSTDELKEE-LIA-DALPVLADRVII  381 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d----~eVr~~AL~aLsnLas~~~~~~~-Lve-giLe~Lv~LL~~  381 (747)
                      .+...+.++.++.++. ...    ..++..++.+|.+++........ +.+ ++++.|+.+|..
T Consensus       203 ~l~~~g~~~~L~~ll~-~~~~~~~~~v~~~al~~L~~L~~~~~~~~~~~~e~~~i~~L~~lL~~  265 (651)
T 3GRL_A          203 IVAFENAFERLLDIIT-EEGNSDGGIVVEDCLILLQNLLKNNNSNQNFFKEGSYIQRMKPWFEV  265 (651)
T ss_dssp             HHHHTTHHHHHHHHHH-HHTGGGSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTCGGGGGGGGCC
T ss_pred             HHHhCChHHHHHHHHH-HhCCCCccHHHHHHHHHHHHHHhCCHHHHHHHHhcChHHHHHHHHhc
Confidence            4445577888888876 322    25777888899998875433333 334 788888888864


No 218
>5AFF_A SYMPORTIN 1, RIBOSOMAL PROTEIN L5; CHAPERONE, RIBOSOME BIOGENESIS, ALPHA SOLENOID.; 3.398A {CHAETOMIUM THERMOPHILUM}
Probab=95.22  E-value=0.00026  Score=78.85  Aligned_cols=94  Identities=14%  Similarity=0.083  Sum_probs=66.2  Template_Neff=8.800

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLV-DLLRSPNQNVQQAAAGALRNLVFRS-TTNK  322 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll-~lL~s~d~eVr~~AL~aLs~La~~~-~~~~  322 (747)
                      ..++.|+..+.+.++..+..++.+|.+++.. +.....+...++++.|+ .++.+.+..++..++.+|.+++... ....
T Consensus        12 ~~i~~Li~~L~s~~~~~r~~A~~aL~~L~~d-~~~r~~ll~~g~v~~Li~~lL~d~~~~v~~~a~~aLrnLs~~~~~~~~   90 (654)
T 5AFF_A           12 DKILPVLKDLKSPDAKSRTTAAGAIANIVQD-AKCRKLLLREQVVHIVLTETLTDNNIDSRAAGWEILKVLAQEEEADFC   90 (654)
T ss_dssp             HHHHHHHHHHHSSCTTHHHHHHHHHHHHHCC-HHHHHHHHHTTHHHHHHHTGGGCSSHHHHHHHHHHHHHHHHHSCHHHH
T ss_pred             CchHHHHHHcCCCCHHHHHHHHHHHHHHHcC-HHHHHHHHHCChHHHHHHHHccCCCHHHHHHHHHHHHHHhccCchhHH
Confidence            3456677777777888899999999998754 44444555567888887 7787777889999999999997643 2222


Q NP_000290.2     323 LETRRQNGIREAVSLLR  339 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~  339 (747)
                      ..++..+++..|..++.
T Consensus        91 ~~l~~~~il~~L~~lL~  107 (654)
T 5AFF_A           91 VHLYRLDVLTAIEHAAK  107 (654)
T ss_dssp             HHHHHTTHHHHHHHHHH
T ss_pred             HHHHHCChHHHHHHHHH
Confidence            33444566666666654


No 219
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=95.19  E-value=0.00023  Score=72.97  Aligned_cols=107  Identities=12%  Similarity=0.043  Sum_probs=72.0  Template_Neff=12.900

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNK  322 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~  322 (747)
                      ...+++.+...+.+.++.++..++.++..+....       ....+++.+...+.+.++.++..++.++..+....+...
T Consensus        84 ~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~  156 (592)
T 6QH5_B           84 AIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMV  156 (592)
T ss_pred             HHHHHHHHHHHccCCCHHHHHHHHHHHHHHcchh-------hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCchhh
Confidence            4445666666777777888888888888775421       112355666666777778889999999888875433211


Q NP_000290.2     323 LETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       323 ~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ....+++.+...+. +.++.++..++.++..+...
T Consensus       157 ---~~~~~~~~l~~~l~-d~~~~vr~~a~~~l~~~~~~  190 (592)
T 6QH5_B          157 ---EDQGFLDSLRDLIA-DSNPMVVANAVAALSEISES  190 (592)
T ss_pred             ---cCccHHHHHHHHhC-CCCHHHHHHHHHHHHHHHhc
Confidence               11245666666675 55678888899988888764


No 220
>3C2G_A Sys-1 protein, Pop-1 8-residue peptide; beta-catenin, phylogeny, SYS-1, POP-1, Caenorhabditis; HET: MSE; 2.5A {Caenorhabditis elegans}
Probab=95.17  E-value=0.00033  Score=77.69  Aligned_cols=189  Identities=17%  Similarity=0.156  Sum_probs=108.5  Template_Neff=5.600

Q NP_000290.2     260 KYQAIGAYYIQHTCFQDESAKQQVYQL-GG----------ICKLVDLLRSP----------------N----QNVQQAAA  308 (747)
Q Consensus       260 eVr~sAL~aLsnLs~~~~~~~~~li~~-~I----------L~~Ll~lL~s~----------------d----~eVr~~AL  308 (747)
                      .+...++.++..++..+......+... +.          +..|+.++...                +    +.+...+.
T Consensus       185 ~~~~~i~d~Lr~L~~~n~~~K~~~l~~~g~~~~~~~~~~~I~~Ll~IL~~~~~~~~~~~~e~~~~~~~~~~~e~ll~~t~  264 (619)
T 3C2G_A          185 MINPAIFIIFRFIISKDTRLKDYFIWNNNPHDQPPPPTGLIIKLNAVMIGSYRLIAGQNPETLPQNPELAHLIQVIIRTF  264 (619)
T ss_dssp             GCCTHHHHHHHHHHTTCHHHHHHHHHTTCCTTSCCCTTSHHHHHHHHHHHHHHHHTTCCGGGGGGCHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHHHHHhcCCHHHHHHHHhcCCCCCCCCCCchHHHHHHHHHHHhHhhhcCCCcccCCCCccHHHHHHHHHHHH
Confidence            344556667777766544443333332 23          56676666531                1    44555666


Q NP_000290.2     309 GALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIPFSGWCD  388 (747)
Q Consensus       309 ~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~~~~~~~  388 (747)
                      .+|..+. ........+...+.++.|...+. ..++.+...++++|.++.........-+++.+..++.+|..       
T Consensus       265 ~lLk~Ls-~~sn~a~~~V~~gGvq~L~~~L~-~~S~rlv~~~L~~LrnlSDa~~~~~~~l~~ll~~lv~ll~~-------  335 (619)
T 3C2G_A          265 DLLGLLL-HDSDAIDGFVRSDGVGAITTVVQ-YPNNDLIRAGCKLLLQVSDAKALAKTPLENILPFLLRLIEI-------  335 (619)
T ss_dssp             HHHHHHC-CSHHHHHHHHHTTHHHHHHHHTT-SSCHHHHHHHHHHHHHHTTCGGGGTSCCTTHHHHHHHHHHH-------
T ss_pred             HHHHHHh-CCcchHHHHHHCCHHHHHHHHcc-CCCHHHHHHHHHHHHHHHchHHHcCCchHHHHHHHHHHHhc-------
Confidence            7777666 33333345666788888888886 67788999999999999865432212223566667776621       


Q NP_000290.2     389 GNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCVAA----  464 (747)
Q Consensus       389 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----  464 (747)
                              .-|+.+..-+||+|..-.                     ....--+.+---.|-|+.|+.-+..+...    
T Consensus       336 --------~~D~~iv~~~tG~LsNlt---------------------~nn~~NK~~~i~~ggi~~Li~~i~~~~~~~~~~  386 (619)
T 3C2G_A          336 --------HPDDEVIYSGTGFLSNVV---------------------AHKQHVKDIAIRSNAIFLLHTIISKYPRLDELT  386 (619)
T ss_dssp             --------CCCHHHHHHHHHHHHHHS---------------------TTCHHHHHHHHHTTHHHHHHHHHHTSCCGGGCC
T ss_pred             --------CCCHHHHHHHHHHHHHHH---------------------cCChhHHHHHHhCCHHHHHHHHHHhCCccccCC
Confidence                    237888888898875311                     11111111111234445555444333210    


Q NP_000290.2     465 ----SRCDDKSVENCMCVLHNLSYRL  486 (747)
Q Consensus       465 ----~~~~~~~~~~~~~~~~~~~~~~  486 (747)
                          -+-...-.|||.|.|+||..+-
T Consensus       387 ~~~~~~~~eeI~e~~l~aLr~Lt~~h  412 (619)
T 3C2G_A          387 DAPKRNRVCEIICNCLRTLNNFLMMW  412 (619)
T ss_dssp             SHHHHHHHHHHHHHHHHHHHHHHGGG
T ss_pred             CCchhhhhHHHHHHHHHHHHHHhccC
Confidence                0011345899999999998874


No 221
>4FDD_A Transportin-1, RNA-binding protein FUS; HEAT repeats, Karyopherin, nuclear import; 2.3A {Homo sapiens}
Probab=95.09  E-value=0.00028  Score=75.31  Aligned_cols=157  Identities=12%  Similarity=0.083  Sum_probs=93.3  Template_Neff=13.300

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.+...+. +.++.++..++.++..++...+.     ..... -..+++.+...+.+.+..++..++.++..++.. 
T Consensus       629 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~  701 (852)
T 4FDD_A          629 NILTLMYQCMQ-DKMPEVRQSSFALLGDLTKACFQ-----HVKPC-IADFMPILGTNLNPEFISVCNNATWAIGEISIQM  701 (852)
T ss_dssp             CHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHCGG-----GTGGG-HHHHHHHHHHTCCTTSHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHHHH-----hHHHH-HHHHHHHHHhhCCcccHHHHHHHHHHHHHHHHHc
Confidence            35566666666 35677888899999988764321     11111 134666677777777788888999999888765 


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ..........+++.+...+...    ..+..++..++.+|..+....+....... ..++..++..+....+..++..++
T Consensus       702 ~~~~~~~~~~i~~~l~~~l~~~----~~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~a~  776 (852)
T 4FDD_A          702 GIEMQPYIPMVLHQLVEIINRP----NTPKTLLENTAITIGRLGYVCPQEVAPML-QQFIRPWCTSLRNIRDNEEKDSAF  776 (852)
T ss_dssp             GGGGGGGTHHHHHHHHHHHTCS----SCCHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHHTSCSSHHHHHHH
T ss_pred             CccchhhHHHHHHHHHHHHcCC----CCChhHHHHHHHHHHHHHHHCHHHhHHHH-HHhHHHHHHHhhcCCCHHHHHHHH
Confidence            2111111123556666666541    01467788888999888765332111111 124445555554322567788888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..++...
T Consensus       777 ~~l~~l~~~~  786 (852)
T 4FDD_A          777 RGICTMISVN  786 (852)
T ss_dssp             HHHHHHHHHC
T ss_pred             HHHHHHHhhC
Confidence            8887776543


No 222
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=95.03  E-value=0.00031  Score=72.53  Aligned_cols=106  Identities=11%  Similarity=0.035  Sum_probs=69.9  Template_Neff=12.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+....       ....+++.+...+.+.++.++..++.++..+....+... 
T Consensus       101 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~-  172 (600)
T 4P6Z_B          101 IMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQLV-  172 (600)
T ss_pred             HHHHHHHHHHccCCCHHHHHHHHHHHhcCCchH-------HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHhhChHHh-
Confidence            344555566666667788888888887775321       112455666666777778888889998888875433211 


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ....+++.+...+. +.++.++..++.++..+...
T Consensus       173 --~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  206 (600)
T 4P6Z_B          173 --EDQGFLDTLKDLIS-DSNPMVVANAVAALSEIAES  206 (600)
T ss_pred             --hccChHHHHHHHhc-CCCHHHHHHHHHHHHHHHhh
Confidence              11345666777775 55678888888888888764


No 223
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=95.01  E-value=0.00032  Score=73.46  Aligned_cols=144  Identities=13%  Similarity=0.048  Sum_probs=89.0  Template_Neff=12.300

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD--VVRSGASLLSNMSR  624 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~e--Vr~~AL~aLsnLa~  624 (747)
                      ..++.|+.++. +.+..++..++.++..+......          ....+++.|...+.+.+..  ++..++++|+.+..
T Consensus       441 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~v~~~a~~~l~~~~~  509 (623)
T 2JKT_A          441 WYVDTILNLIR-IAGDYVSEEVWYRVIQIVINRDD----------VQGYAAKTVFEALQAPACHENLVKVGGYILGEFGN  509 (623)
T ss_dssp             HHHHHHHHHTT-TTGGGCCHHHHHHHHHHHHHCST----------THHHHHHHHHHHTTSSSCCHHHHHHHHHHHHHSST
T ss_pred             HHHHHHHHHHH-HHcccCCHHHHHHHHHHHhcChh----------HHHHHHHHHHHHHhCccCCHHHHHHHHHHHHHHHH
Confidence            35666777776 35566777788888777653211          1234566666666655544  78888888888775


Q NP_000290.2     625 HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC---RSSASPKA  700 (747)
Q Consensus       625 ~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL---~s~~d~eV  700 (747)
                      .... .......+++.|...+.+      .+..++..++.+|..++...+.     . ...+..++..+   .+. ++.+
T Consensus       510 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~al~~l~~~~~~-----~-~~~l~~ll~~l~~~~~~-~~~v  576 (623)
T 2JKT_A          510 LIAGDPRSSPLIQFNLLHSKFHL------CSVPTRALLLSTYIKFVNLFPE-----V-KATIQDVLRSDSQLKNA-DVEL  576 (623)
T ss_dssp             TSSSSGGGCHHHHHHHHHHHHTT------SCHHHHHHHHHHHHHHHHHCTT-----T-HHHHHTTSSSHHHHTCS-SHHH
T ss_pred             HhcCCCCCChHHHHHHHHHhcCC------CCHHHHHHHHHHHHHHHHhCHH-----H-HHHHHHHHHhccccCCC-CHHH
Confidence            4111 111111355566666655      3577889999999998864332     1 13455555555   444 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       577 r~~a~~~l~~~~~~  590 (623)
T 2JKT_A          577 QQRAVEYLRLSTVA  590 (623)
T ss_dssp             HHHHHHHHHHHHSS
T ss_pred             HHHHHHHHHHhccC
Confidence            99999998877654


No 224
>5IZ8_A Adenomatous polyposis coli protein, ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2; APC, ASEF, Colon CANCER, Drug; HET: PGE; 3.06A {Homo sapiens}
Probab=94.95  E-value=0.00036  Score=67.82  Aligned_cols=162  Identities=22%  Similarity=0.254  Sum_probs=121.7  Template_Neff=12.000

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQIARLLQSGN----SDVVRSGAS  617 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~Ll~LL~s~d----~eVr~~AL~  617 (747)
                      +.+.++++.|+.++....++.++..++++|.+++...+.     ....+.+ .++++.|+.++...+    ..++..++.
T Consensus       166 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~  240 (354)
T 5IZ8_A          166 LREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGG  240 (354)
T ss_dssp             HHHTTHHHHHHHHHHHCCSHHHHHHHHHHHHHHHTSCHH-----HHHHHHTSTTHHHHHHHHTTCCCTTSCCHHHHHHHH
T ss_pred             HHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChH-----hHHHHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHH
Confidence            356778888888887225677888999999999875232     2334455 688899998887533    678888999


Q NP_000290.2     618 LLSNMSR----HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       618 aLsnLa~----~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      +|.+++.    .... ..+...++++.++.++..      .++.++..++.+|.+++...+.....+.+.++++.|+.++
T Consensus       241 ~L~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l  314 (354)
T 5IZ8_A          241 ILRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLI  314 (354)
T ss_dssp             HHHHHHHHHHTCHHHHHHHHTTTHHHHHHHTTTC------SCHHHHHHHHHHHHHHSSSCHHHHHHHHTTTHHHHHHHHS
T ss_pred             HHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhhc------CCHHHHHHHHHHHHHHHccCHHHHHHHHhCCHHHHHHHHH
Confidence            9999873    2222 233455678888888876      3677899999999999985466666677778889999988


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .+. ++.++..++.+|.+++...+
T Consensus       315 ~~~-~~~v~~~a~~~L~~l~~~~~  337 (354)
T 5IZ8_A          315 HSK-HKMIAMGSAAALRNLMANRP  337 (354)
T ss_dssp             SCS-SHHHHHHHHHHHHHHHTTCC
T ss_pred             hcc-CHHHHHHHHHHHHHHHccCc
Confidence            866 78899999999999997764


No 225
>5IZA_A Adenomatous polyposis coli protein, ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2; APC, ASEF, Colon CANCER, Drug; 1.5A {Homo sapiens}
Probab=94.95  E-value=0.00036  Score=67.81  Aligned_cols=162  Identities=22%  Similarity=0.254  Sum_probs=121.8  Template_Neff=12.000

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLK-EKGLPQIARLLQSGN----SDVVRSGAS  617 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie-~giI~~Ll~LL~s~d----~eVr~~AL~  617 (747)
                      +.+.++++.|+.++....++.++..++++|.+++...+.     ....+.+ .++++.|+.++...+    ..++..++.
T Consensus       166 ~~~~~~~~~l~~~l~~~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~  240 (354)
T 5IZA_A          166 LREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE-----NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGG  240 (354)
T ss_dssp             HHHTTHHHHHHHHHHHCCCHHHHHHHHHHHHHHHTTCHH-----HHHHHHTSTTHHHHHHHHTCSSCSSCCHHHHHHHHH
T ss_pred             HHHCCHHHHHHHHHHhcCCHHHHHHHHHHHHHHHcCChH-----hHHHHHhhccHHHHHHHHHhhcCCCCcHHHHHHHHH
Confidence            356778888888887225677888999999999875232     2334455 688899998887533    678888999


Q NP_000290.2     618 LLSNMSR----HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       618 aLsnLa~----~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      +|.+++.    .... ..+...++++.++.++..      .++.++..++.+|.+++...+.....+.+.++++.|+.++
T Consensus       241 ~L~~l~~~~~~~~~~~~~l~~~~~~~~l~~~l~~------~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l  314 (354)
T 5IZA_A          241 ILRNVSSLIATNEDHRQILRENNCLQTLLQHLKS------HSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLI  314 (354)
T ss_dssp             HHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTSSCHHHHHHHHHTTHHHHHHTTT
T ss_pred             HHHHHHHHhcCCHHHHHHHHHCCHHHHHHHHhhc------CCHHHHHHHHHHHHHHHccCHHHHHHHHhCCHHHHHHHHH
Confidence            9999873    2222 233455678888888876      3677899999999999985466666677778889999988


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .+. ++.++..++.+|.+++...+
T Consensus       315 ~~~-~~~v~~~a~~~L~~l~~~~~  337 (354)
T 5IZA_A          315 HSK-HKMIAMGSAAALRNLMANRP  337 (354)
T ss_dssp             TCS-SHHHHHHHHHHHHHHHHTCC
T ss_pred             hcc-CHHHHHHHHHHHHHHHccCc
Confidence            866 78899999999999997764


No 226
>5YVI_A Transportin-1, RNA-binding protein FUS; Importin family, PROTEIN TRANSPORT, PROTEIN; 2.9A {Homo sapiens}
Probab=94.92  E-value=0.00036  Score=74.50  Aligned_cols=156  Identities=12%  Similarity=0.081  Sum_probs=94.0  Template_Neff=13.300

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.+..++..++.++..++...
T Consensus       645 ~~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~l~~l~~~l~~~~~~v~~~a~~~l~~l~~~~  717 (868)
T 5YVI_A          645 NILTLMYQCMQ-DKMPEVRQSSFALLGDLTKACFQ-----HVKP-CIADFMPILGTNLNPEFISVCNNATWAIGEISIQM  717 (868)
T ss_dssp             CHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHCHH-----HHGG-GHHHHHHHHHHTCCTTSHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHhHH-----hHHH-HHHHHHHHHHhcCCcccHHHHHHHHHHHHHHHHHc
Confidence            34555666665 35677888899999888764321     0111 11346666777777777888999999999888652


Q NP_000290.2     627 -LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 -e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                       .........+++.+...+.+.    ..+..++..++.+|..++...+....... ..+++.++..+.+..++.++..++
T Consensus       718 ~~~~~~~~~~i~~~l~~~l~~~----~~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~r~~~~  792 (868)
T 5YVI_A          718 GIEMQPYIPMVLHQLVEIINRP----NTPKTLLENTAITIGRLGYVCPQEVAPML-QQFIRPWCTSLRNIRDNEEKDSAF  792 (868)
T ss_dssp             GGGGGGGGGGTHHHHHHHHTCT----TCCHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHTTSCSSHHHHHHH
T ss_pred             cccchhcHHHHHHHHHHHhcCC----CCChhHHHHHHHHHHHHHHHCHHHHHHHH-HHHHHHHHHHhhcCCChHHHHHHH
Confidence             111111123566666666541    01467888899999988865332111111 234555555555322567888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       793 ~~l~~l~~~  801 (868)
T 5YVI_A          793 RGICTMISV  801 (868)
T ss_dssp             HHHHHC-CC
T ss_pred             HHHHHHHhh
Confidence            888888754


No 227
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=94.91  E-value=0.00038  Score=73.02  Aligned_cols=108  Identities=17%  Similarity=0.103  Sum_probs=69.7  Template_Neff=12.200

Q NP_000290.2     242 CSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL--RSPNQNVQQAAAGALRNLVFRST  319 (747)
Q Consensus       242 ~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL--~s~d~eVr~~AL~aLs~La~~~~  319 (747)
                      ....+++.+...+.+.++.++..++.++..+....       ....+++.+...+  .+.++.++..++.++..+.....
T Consensus       108 ~~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~-------~~~~l~~~l~~~l~~~~~~~~vr~~a~~~L~~~~~~~~  180 (621)
T 6QH7_A          108 LIRLINNAIKNDLASRNPTFMGLALHCIANVGSRE-------MAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSP  180 (621)
T ss_dssp             HHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHH-------HHHHHTTHHHHHHTTSCCCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHHHHHHhcCCHHHHHHHHHHHHhhCCHH-------HHHHHHhhHHHHHHcCCCCHHHHHHHHHHHHHHHHHCh
Confidence            33445556666666677788888888888775421       1123455566666  66677888888888888765332


Q NP_000290.2     320 TNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       320 ~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ...   .....++.+...+. +.++.++..++.++..+...
T Consensus       181 ~~~---~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  217 (621)
T 6QH7_A          181 DLV---PMGDWTSRVVHLLN-DQHLGVVTAATSLITTLAQK  217 (621)
T ss_dssp             GGC---CCCTTHHHHHHGGG-CSSHHHHHHHHHHHHHHHTT
T ss_pred             hhc---CccchHHHHHHHhc-CCCHHHHHHHHHHHHHHHHh
Confidence            211   11245566667775 55677888888888887753


No 228
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=94.85  E-value=0.0004  Score=70.07  Aligned_cols=146  Identities=11%  Similarity=0.055  Sum_probs=95.0  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+..++. +.+..++..++.+|..+......      . . ....+++.+...+.+.+..++..++.++..+....
T Consensus       441 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~  511 (588)
T 1B3U_A          441 KLNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK------E-W-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVC  511 (588)
T ss_dssp             HHHHHHHHGGG-CSSHHHHHHHHHHHHHHHHHHCH------H-H-CCCCCHHHHHHTTTCSCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHhc-CChHHHHHHHHHHHHHHHHHhCh------H-H-HHHhHHHHHHHhhcCCCHHHHHHHHHHHHHHHHHh
Confidence            34566667776 46677888888888888764221      1 1 12356677777777777888888888888887642


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .. ......+++.+...+.+      .++.++..++.++..+......   ......+++.+...+.+. ++.++..+..
T Consensus       512 ~~-~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  580 (588)
T 1B3U_A          512 GQ-DITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQE  580 (588)
T ss_dssp             HH-HHCCCCCHHHHHHGGGC------SCHHHHHHHHHHHHHHGGGSCH---HHCCCCCHHHHHHHTTCS-SHHHHHHHHH
T ss_pred             CH-HHHHhchHHHHHHHhCC------CcHHHHHHHHHHHHHHHHHhcC---CcchHHHHHHHHHHhcCC-ChhHHHHHHH
Confidence            11 11123455666666665      3678899999999988754211   112224566677777765 7788888888


Q NP_000290.2     707 LLSDMW  712 (747)
Q Consensus       707 aLsnL~  712 (747)
                      ++..+.
T Consensus       581 ~l~~l~  586 (588)
T 1B3U_A          581 ALTVLS  586 (588)
T ss_dssp             HHHHTT
T ss_pred             HHHHhh
Confidence            887765


No 229
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=94.77  E-value=0.00057  Score=75.04  Aligned_cols=161  Identities=14%  Similarity=0.093  Sum_probs=111.6  Template_Neff=8.100

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-----SG----NSDV  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-----s~----d~eV  611 (747)
                      +.+.++++.|+.+|.. .  ....+..|+.+|.+|+...+.     ....+.+.++++.|+.+|.     ++    ....
T Consensus       241 i~~~g~l~~Ll~lL~~-~~~~~~~k~~AaeiL~~L~~~~~~-----~r~~l~~~g~I~~LL~lL~~y~~~d~~~~~e~e~  314 (568)
T 4HM9_A          241 GAQQGLLQWLLKRLKA-KMPFDANKLYCSEVLAILLQDNDE-----NRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEM  314 (568)
T ss_dssp             HCCCCCHHHHHHHHHS-SCCCCHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHHHHHGGGTTSCCSSSHHHHH
T ss_pred             HHHCCHHHHHHHHHHc-CCCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCchHHHHHHHHHhhhccCCCCHHHHHH
Confidence            3567889999999983 3  466778899999999875332     2444456889999999995     11    1234


Q NP_000290.2     612 VRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS--QPQLAKQYFSSSMLNNI  688 (747)
Q Consensus       612 r~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~--s~e~~~~Lve~giL~~L  688 (747)
                      ...++.+|.+++..+.. ..++..++++.++.+|..       ....+..|+.+|..++..  .......+++.+++..|
T Consensus       315 ~en~~~aL~~L~~~~~~r~~f~~~~gv~lLv~lL~~-------~~~~~~~Al~vL~~a~~~~~~~~~~~~~ve~ggl~~L  387 (568)
T 4HM9_A          315 MENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLRE-------KKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTI  387 (568)
T ss_dssp             HHHHHHHHHHHTTSTHHHHHHHHTTHHHHHHHHHHH-------TSTTHHHHHHHHHHHHCSGGGHHHHHHHHHTTCHHHH
T ss_pred             HHHHHHHHHHHhCCHHHHHHHHHCChHHHHHHHHhC-------ChhHHHHHHHHHHHHhcCCCChhHHHHHHHHchHHHH
Confidence            55668888888876544 355666788888888875       234567778888665442  34456677777888888


Q NP_000290.2     689 INLCRSS---------ASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       689 l~LL~s~---------~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.++...         ......+.++.+|..|+....
T Consensus       388 ~~ll~~~~~~~~~~~~~~~e~~E~~~~iL~sL~~~~~  424 (568)
T 4HM9_A          388 FPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLR  424 (568)
T ss_dssp             HHHHHSCCCCCSSSSCCHHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHhcCcchhcCCCCCHHHHHHHHHHHHHHHHhcCC
Confidence            8876532         134567888888888886543


No 230
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=94.76  E-value=0.00048  Score=72.19  Aligned_cols=144  Identities=13%  Similarity=0.054  Sum_probs=85.0  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD--VVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~e--Vr~~AL~aLsnLa~~  625 (747)
                      .++.|+..+. +.++.++..++.++..+......          ....+++.+...+.+.+..  ++..++++++.+...
T Consensus       442 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~~~~~  510 (621)
T 6QH5_A          442 YVDTILNLIR-IAGDYVSEEVWYRVIQIVINRDD----------VQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNL  510 (621)
T ss_pred             HHHHHHHHhc-CCCHHHcHHHHHHHHHHHhcCHH----------HHHHHHHHHHHHhhCCCCCHHHHHHHHHHHHHHHhh
Confidence            4556666665 34556666777777766543111          1233455666666655544  777788888777654


Q NP_000290.2     626 P-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC---RSSASPKAA  701 (747)
Q Consensus       626 ~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL---~s~~d~eVr  701 (747)
                      . .........+++.|...+.+      .+..++..++.+|..+....+.     . ...+..++..+   .+. ++.++
T Consensus       511 ~~~~~~~~~~~~~~~L~~~l~~------~~~~vr~~a~~al~~l~~~~~~-----~-~~~l~~ll~~l~~~~~~-~~~vr  577 (621)
T 6QH5_A          511 IAGDPRSSPLIQFNLLHSKFHL------CSVPTRALLLSTYIKFVNLFPE-----V-KATIQDVLRSDSQLKNA-DVELQ  577 (621)
T ss_pred             CCCCCCCCHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhCHH-----H-HhHHHHHHHHHHhcCCC-CHHHH
Confidence            1 11110111245556666655      3567888899999988764322     1 12344555544   444 77889


Q NP_000290.2     702 EAARLLLSDMWSSK  715 (747)
Q Consensus       702 ~aAL~aLsnL~~~~  715 (747)
                      ..++.++..+....
T Consensus       578 ~~a~~~l~~~~~~~  591 (621)
T 6QH5_A          578 QRAVEYLRLSTVAS  591 (621)
T ss_pred             HHHHHHHHHhCCCc
Confidence            99999988876543


No 231
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=94.68  E-value=0.00052  Score=58.87  Aligned_cols=134  Identities=25%  Similarity=0.276  Sum_probs=89.8  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++...+.....+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~  126 (202)
T 5MFO_F           47 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  126 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666777777888899999999886544333334444577777777777777888889999998876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..+..++..++.++..++..... ...+.. ++++.|..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (202)
T 5MFO_F          127 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQS  182 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHTTTT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcChHHHHHHHHHCCHHHHHHHHHc
Confidence            34456777777776 55677888888999888875322 222222 56666666664


No 232
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=94.66  E-value=0.00054  Score=58.80  Aligned_cols=134  Identities=25%  Similarity=0.276  Sum_probs=89.7  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++.++.+++.........+...++++.+...+.+.+..++..++.++..++.........+
T Consensus        47 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  126 (202)
T 5MFO_E           47 ALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASGGNEQIQAV  126 (202)
T ss_dssp             HHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHhhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            45566666777778888899999999886544333334444577777777777777888889999988876543333333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..+..++..++.++..++..... ...+.. ++++.|..++.
T Consensus       127 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  182 (202)
T 5MFO_E          127 IDAGALPALVQLLS-SPNEQILQEALWALSNIASGGNEQKQAVKEAGAEPALEQLQS  182 (202)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHHHHHHHHHTTHHHHHHHHTT
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHhcCHHHHHHHHHHCCHHHHHHHHHc
Confidence            33456777777776 55677888889999888875322 222222 56666666654


No 233
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=94.63  E-value=0.00067  Score=72.78  Aligned_cols=161  Identities=14%  Similarity=0.093  Sum_probs=111.4  Template_Neff=8.700

Q NP_000290.2     543 LYHSDAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-----SG----NSDV  611 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-----s~----d~eV  611 (747)
                      +.+.++++.|+.++.. .  ....+..++.+|.+++...+.     ....+.+.++++.|+.++.     ++    ....
T Consensus       163 i~~~~~l~~Ll~~L~~-~~~~~~~k~~a~~~L~~L~~~~~~-----~~~~l~~~g~i~~Ll~lL~~~~~~d~~~~~~~e~  236 (490)
T 4MFU_A          163 GAQQGLLQWLLKRLKA-KMPFDANKLYCSEVLAILLQDNDE-----NRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEM  236 (490)
T ss_dssp             HCCCCCHHHHHHHHHC-CSCCCHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHHHHHHTTSSSCCSSHHHHHH
T ss_pred             HHHCCHHHHHHHHHHc-CCCCHHHHHHHHHHHHHHHcCCHH-----HHHHHHhCchHHHHHHHHHhhhhcCCCCHHHHHH
Confidence            3567889999999983 3  467788899999999875332     2444456789999999985     11    1234


Q NP_000290.2     612 VRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS--QPQLAKQYFSSSMLNNI  688 (747)
Q Consensus       612 r~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~--s~e~~~~Lve~giL~~L  688 (747)
                      ...++.+|++++..+.. ..++..++++.++.++..       ....+..|+.+|...+..  ++.....+++.+++..|
T Consensus       237 ~en~~~aL~~L~~~~~~~~~f~~~~gi~llv~lL~~-------~~~~~~~AL~~L~~a~~~~~~~~~~~~~v~~ggl~~L  309 (490)
T 4MFU_A          237 MENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLRE-------KKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTI  309 (490)
T ss_dssp             HHHHHHHHHHHHHSTHHHHHHHHTTHHHHHHHHHHT-------TSSTHHHHHHHHHHHHSSGGGHHHHHHHHHTTHHHHH
T ss_pred             HHHHHHHHHHHhCCHHHHHHHHHCCcHHHHHHHHhC-------ChhHHHHHHHHHHHHhcCCCCHHHHHHHHHHchHHHH
Confidence            45568888888876444 355666788888888865       234566677777665442  34456677777888888


Q NP_000290.2     689 INLCRSS---------ASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       689 l~LL~s~---------~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      +.++...         .+..+.+.++.+|..|+....
T Consensus       310 ~~~l~~~~~~~~~~~~~~~~~~E~~~~il~sL~~~~~  346 (490)
T 4MFU_A          310 FPLFMKSPRKIKKVGTTEKEHEEHVCSILASLLRNLR  346 (490)
T ss_dssp             HHHHHCCCCSCCSSCCCSHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHhcCcccccCCCCCHHHHHHHHHHHHHHHHhcCC
Confidence            8877542         134677888899888887543


No 234
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=94.58  E-value=0.00059  Score=68.47  Aligned_cols=145  Identities=11%  Similarity=0.056  Sum_probs=94.9  Template_Neff=13.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+..++. +.++.++..++.+|..+......      . . ....+++.+...+.+.+..++..++.++..+.....
T Consensus       436 ~~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~  506 (582)
T 2NYL_A          436 LNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK------E-W-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCG  506 (582)
T ss_dssp             CHHHHHHGGG-CSSHHHHHHHHHHHHHHHHHHHH------H-H-HHHHTHHHHHHTTTCSSHHHHHHHHHHHHHHGGGSC
T ss_pred             HHHHHHHHhc-CCHHHHHHHHHHHHHHHHHHHCh------h-h-HHhcHHHHHHHhcCCCcHHHHHHHHHHHHHHHHHhC
Confidence            4555666776 46777888899998888764221      1 1 124566777777777778888888998888876421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .. .....+++.+...+.+      .++.++..++.++..+......   ......+++.+...+.+. ++.++..++.+
T Consensus       507 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~~  575 (582)
T 2NYL_A          507 QD-ITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQEA  575 (582)
T ss_dssp             HH-HHHHHTHHHHHHTSSC------SSHHHHHHHHHHHTTSSTTSCH---HHCCCCCHHHTTTTTTCS-SHHHHHHHHTT
T ss_pred             HH-HHHhcHHHHHHHHhcC------ChHHHHHHHHHHHHHHHHHcCC---CCcHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            11 1123355666666665      3678889999999988764211   112224566677777665 77888888888


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      +..++
T Consensus       576 l~~l~  580 (582)
T 2NYL_A          576 LTVLS  580 (582)
T ss_dssp             TTTTT
T ss_pred             HHHhc
Confidence            88765


No 235
>4U2X_F eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=94.35  E-value=0.00082  Score=57.14  Aligned_cols=73  Identities=21%  Similarity=0.253  Sum_probs=49.2  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      +++.+...+.+.++.++..++.++.+++.. .+.....+...++++.+...+...++.++..++.++.+++...
T Consensus        51 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~  124 (175)
T 4U2X_F           51 IFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLG  124 (175)
T ss_dssp             CHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhCCHHHHHHHHHHHHHHhcCCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHhcc
Confidence            455555666666677888888999888753 2223333334466777777777666777888888888887643


No 236
>3SL9_B Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: GOL, EDO, PEG, IMD; 2.2A {Homo sapiens}
Probab=94.35  E-value=0.00082  Score=56.48  Aligned_cols=110  Identities=24%  Similarity=0.309  Sum_probs=73.4  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.. .+..++..++.++.+++.. +.....+...++++.+..++...++.++..++.++.+++.........
T Consensus        56 ~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~  134 (167)
T 3SL9_B           56 MVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA  134 (167)
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHHHHHHHCCcHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHhHHHH
Confidence            55566666665 5677888889999888743 333334444567788888887777788888999999888654332222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNL  357 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnL  357 (747)
                      ....++++.+..++. ..++.++..++.++..+
T Consensus       135 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l  166 (167)
T 3SL9_B          135 VRLAGGLQKMVALLN-KTNVKFLAITTDCLQIL  166 (167)
T ss_pred             HHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHh
Confidence            222456777777776 45566777777776654


No 237
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=94.34  E-value=0.0008  Score=67.65  Aligned_cols=110  Identities=11%  Similarity=0.101  Sum_probs=57.6  Template_Neff=13.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL-E  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~-~  324 (747)
                      +++.+...+.+.++.++..++.++..+......   ......+++.+...+.+.++.++..++.++..+......... .
T Consensus       239 ~~~~l~~~l~~~~~~vr~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~  315 (584)
T 4I5L_D          239 VMPTLRQAAEDKSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENLSADCREN  315 (584)
T ss_dssp             THHHHHHHHTCSSHHHHHHHHHTHHHHHHHHHH---HHCCCCCHHHHHHHHTCSSHHHHHHHHTTHHHHHHTSCTTTHHH
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHHHHHHHCC---CCChhhHHHHHHHHhcCCcHHHHHHHHHHHHHHHHhcCccchhh
Confidence            334444455555666777777777666543221   111123455566666666667777777777776643221110 0


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      .....+++.+...+. +.++.++..++.++..+..
T Consensus       316 ~~~~~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~  349 (584)
T 4I5L_D          316 VIMSQILPCIKELVS-DANQHVKSALASVIMGLSP  349 (584)
T ss_dssp             HCCCCCHHHHHHHHT-CSCHHHHHHHHTTGGGGHH
T ss_pred             HHHHhHHHHHHHHcc-CCCHHHHHHHHHHHHHHHH
Confidence            111234455555554 3445566666666665544


No 238
>4U2X_E eVP24, KPNA5C; eVP24, importin alpha6, immune antagonist; 3.153A {Zaire ebolavirus}
Probab=94.27  E-value=0.00091  Score=56.83  Aligned_cols=73  Identities=21%  Similarity=0.253  Sum_probs=49.3  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQ-DESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~-~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      +++.+...+.+.++.++..++.++.+++.. .......+...+.++.+...+.+.++.++..++.++.+++...
T Consensus        51 ~i~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~  124 (175)
T 4U2X_E           51 IFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVALGCIKPLCDLLTVMDSKIVQVALNGLENILRLG  124 (175)
T ss_dssp             CHHHHHHHHHHSCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHTCHHHHHHGGGCSCHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHhcCHHHHHHHHHHHHHHcCCCCHHHHHHHHHCCcHHHHHHHhcCCCHHHHHHHHHHHHHHHhhc
Confidence            445555666666677888889999988753 2222333334456777777777667778888888888887654


No 239
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=94.24  E-value=0.00095  Score=70.34  Aligned_cols=106  Identities=12%  Similarity=0.039  Sum_probs=70.7  Template_Neff=12.200

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+....       ....+++.+...+.+.++.++..++.++..+........ 
T Consensus        85 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~-------~~~~l~~~l~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~-  156 (657)
T 4UQI_B           85 IMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDK-------ITEYLCEPLRKCLKDEDPYVRKTAAVCVAKLHDINAQMV-  156 (657)
T ss_pred             HHHHHHHHHHhcCCCHHHHHHHHHHHhhcCCch-------hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCHHHh-
Confidence            445555666666677788888888888775421       112355666666777778888889988888875433221 


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ....+++.+...+. +.++.++..++.++..+...
T Consensus       157 --~~~~~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~  190 (657)
T 4UQI_B          157 --EDQGFLDSLRDLIA-DSNPMVVANAVAALSEISES  190 (657)
T ss_pred             --cCcchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhc
Confidence              12245666777776 55678888899988888764


No 240
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=94.04  E-value=0.0013  Score=79.08  Aligned_cols=155  Identities=11%  Similarity=0.032  Sum_probs=110.7  Template_Neff=9.500

Q NP_000290.2     544 YHSDAIRTYLNLM---GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIG----------------------LKEKGLP  598 (747)
Q Consensus       544 ve~G~I~~LL~LL---~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~ll----------------------ie~giI~  598 (747)
                      +..++++.|..++   . +.++.++..|+.+|..++.....     ....+                      ...++++
T Consensus       506 ~~~~~l~~L~~ll~~~~-d~~~~vR~~a~~~l~~la~~~~~-----~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~~  579 (1454)
T 5KC2_B          506 FVDYLLPRLKRLLISNR-QNTNYLRIVFANCLSDLAIIINR-----FQEFTFAQHCNDNSMDNNTEIMESSTKYSAKLIQ  579 (1454)
T ss_pred             HHcCcHHHHHHHHcCCC-CCcHHHHHHHHHHHHHHhcCCCC-----cceEEhhHHhhhHHHHHHHHHHHHHHHHHcCHHH
Confidence            4667888899988   7 47788899999999988754221     01111                      1245667


Q NP_000290.2     599 QIARLLQS----GNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       599 ~Ll~LL~s----~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      .|..++..    .++.++..|+.+|..+.......... .++++.|..++.+      .++.++..|+.+|..|+...  
T Consensus       580 ~l~~ll~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~-~~~l~~L~~~l~d------~~~~vR~~a~~al~~l~~~~--  650 (1454)
T 5KC2_B          580 SVEDLTVSFLTDNDTYVKMALLQNILPLCKFFGRERTN-DIILSHLITYLND------KDPALRVSLIQTISGISILL--  650 (1454)
T ss_pred             HHHHHHHhhcCCCCHHHHHHHHHHHHHHhcCcCchhHH-hhhHHHHHHHccC------CCHHHHHHHHHHHHHHHHhh--
Confidence            77777765    78899999999999987652221111 4567888888876      47899999999999998743  


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ....+++.. ++.|+.+|.+. ++.++..++.+|..|+...
T Consensus       651 ~~~~~~~~~-lp~L~~lL~d~-~~~vr~~al~aL~~L~~~~  689 (1454)
T 5KC2_B          651 GTVTLEQYI-LPLLIQTITDS-EELVVISVLQSLKSLFKTG  689 (1454)
T ss_pred             HHHHHHHcC-HHHHHHHhcCC-CHHHHHHHHHHHHHHhhCC
Confidence            333444433 88888888876 7888999999999887655


No 241
>3SL9_E Catenin beta-1, B-cell CLL/lymphoma 9; Armadillo repeat, components of the; HET: PEG, GOL, IMD, EDO; 2.2A {Homo sapiens}
Probab=94.03  E-value=0.0012  Score=55.43  Aligned_cols=110  Identities=24%  Similarity=0.309  Sum_probs=72.2  Template_Neff=12.600

Q NP_000290.2     246 TIPKAVQYLSS-QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~s-sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.. .+..++..++.++.+++.. ......+...++++.+..++...+..++..++.++.+++.........
T Consensus        56 ~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~-~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~  134 (167)
T 3SL9_E           56 MVSAIVRTMQNTNDVETARCTAGTLHNLSHH-REGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMA  134 (167)
T ss_dssp             HHHHHHHHHHHCCCHHHHHHHHHHHHHHTTS-HHHHHHHHHTTHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHCTTHHHH
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHHcCC-HhHHHHHHHCCcHHHHHHHhCCCCHHHHHHHHHHHHHHHcCCHhHHHH
Confidence            55566666665 5667888888898888743 333333444567777888887777788888999998887654332222


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNL  357 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnL  357 (747)
                      ....++++.+..++. ..++.++..++.++..+
T Consensus       135 ~~~~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l  166 (167)
T 3SL9_E          135 VRLAGGLQKMVALLN-KTNVKFLAITTDCLQIL  166 (167)
T ss_dssp             HHHTTHHHHHHHHHH-HSCGGGHHHHHHHHHHH
T ss_pred             HHHcCHHHHHHHHhc-CCCHHHHHHHHHHHHHh
Confidence            222456777777776 45566777777766654


No 242
>3VWA_B Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; HET: MSE; 2.2A {Saccharomyces cerevisiae}
Probab=93.76  E-value=0.0017  Score=68.89  Aligned_cols=150  Identities=11%  Similarity=0.077  Sum_probs=108.5  Template_Neff=10.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.++..+. +.++.++..++.+|..++.....      . . ....+++.|..++.+.++.++..++.+|+.++..
T Consensus       379 ~~~l~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~ll~~l~~~l~d~~~~vR~~a~~~l~~i~~~  449 (560)
T 3VWA_B          379 SRIYPHFIQGLT-DSDATLRLQTLKTIPCIVSCLTE------R-Q-LNNELLRFLAKTQVDSDVEIRTWTVIIISKISTI  449 (560)
T ss_dssp             CCCHHHHHHGGG-CSCHHHHHHHHHHHHHHGGGSCH------H-C-CCCCHHHHHHHHTTCSSHHHHHHHHHHHHHHHTT
T ss_pred             hchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhCCH------H-H-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHH
Confidence            457788888887 47788999999999998864221      1 1 2356788888888888899999999999999876


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .++.++..|+.+|..++....  ... +...+++.|..++.+. +..++..|
T Consensus       450 ~~~~~~~~~~~l~~~l~~~l~d------~~~~vR~aa~~~l~~~~~~~~--~~~-~~~~~lp~l~~~l~d~-~~~VR~~a  519 (560)
T 3VWA_B          450 LSTSVGNRSNILATAFTKSLKD------PQVKPRLAALYGLEKSIELFD--VNT-IANKILTVIAPGLLDK-SPIVRGRA  519 (560)
T ss_dssp             SSSCHHHHHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHTGGGSC--HHH-CCCCCHHHHGGGGGCS-SHHHHHHH
T ss_pred             hccccchhHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHCC--HHH-HHHHHHHHHHHHHCCC-CHHHHHHH
Confidence            211 111123455666677765      478899999999999886422  112 2245788888888877 88999999


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       520 ~~~l~~~~~~  529 (560)
T 3VWA_B          520 KILFEEYLEK  529 (560)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            9999888754


No 243
>5DFZ_B Vacuolar protein sorting-associated protein 38; Vps34, Vps15, Vps30, Vps38, Autophagy; 4.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=93.74  E-value=0.0018  Score=77.73  Aligned_cols=155  Identities=10%  Similarity=0.029  Sum_probs=111.5  Template_Neff=9.900

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++++.|+.+|. +.++.+|..|+.+|..+......       .. .....++.|+.++.+.++.++..|+.+|..+...
T Consensus       608 ~~~l~~Li~ll~-d~~~~VR~~a~~aL~~i~~~~~~-------~~-~~~~~i~~L~~~l~d~~~~vR~~a~~aL~~~~~~  678 (1460)
T 5DFZ_B          608 DIILSHLITYLN-DKDPALRVSLIQTISGISILLGT-------VT-LEQYILPLLIQTITDSEELVVISVLQSLKSLFKT  678 (1460)
T ss_pred             HhHHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhcCc-------hh-hchhHHHHHHHHhcCCCHHHHHHHHHHHHHhcCC
Confidence            357888888888 57889999999999998864221       11 1234578888899988899999999999766543


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ......+..++++.|..++.+      .++.++..|+.+|..+.......   .....+++.|+.++.+. ++.++..|+
T Consensus       679 ~~~~~~~~~~~i~~l~~~l~d------~~~~VR~~A~~al~~l~~~~~~~---~~~~~~l~~L~~~l~d~-~~~vr~~a~  748 (1460)
T 5DFZ_B          679 GLIRKKYYIDISKTTSPLLLH------PNNWIRQFTLMIIIEIINKLSKA---EVYCILYPIIRPFFEFD-VEFNFKSMI  748 (1460)
T ss_pred             cchhhcccchhHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCH---HHHHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            222111112367778888876      47889999999999987642111   11234688888888877 889999999


Q NP_000290.2     706 LLLSDMWSSKELQG  719 (747)
Q Consensus       706 ~aLsnL~~~~~~~~  719 (747)
                      .+|..+..+...+-
T Consensus       749 ~aL~~~~~~~~~~~  762 (1460)
T 5DFZ_B          749 SCCKQPVSRSVYNL  762 (1460)
T ss_pred             HHhCCCCCHHHHHH
Confidence            99999887776664


No 244
>6HWP_A A3_bGFPD; alphaRep, artificial protein, chimera, bidomain; 2.547A {synthetic construct}
Probab=93.71  E-value=0.0016  Score=62.80  Aligned_cols=91  Identities=14%  Similarity=0.155  Sum_probs=54.4  Template_Neff=12.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ..++.+...+.+.+..++..++..+..+..           ..+++.+...+.+.++.++..++..+..+..        
T Consensus        23 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~-----------~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~--------   83 (409)
T 6HWP_A           23 EKVEMYIKNLQDDSYYVRRAAAYALGKIGD-----------ERAVEPLIKALKDEDAWVRRAAADALGQIGD--------   83 (409)
T ss_dssp             CCHHHHHHGGGCSSHHHHHHHHHHHHHSCC-----------GGGHHHHHHHTTCSSHHHHHHHHHHHHHHTC--------
T ss_pred             HHHHHHHHHccCCCHHHHHHHHHHHHHhcC-----------HhhHHHHHHHhcCCCHHHHHHHHHHHHHhcC--------
Confidence            445556666666677778888877776643           1234445555556667777777777766543        


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                         ...++.+...+. +.++.++..++.++..+.
T Consensus        84 ---~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  113 (409)
T 6HWP_A           84 ---ERAVEPLIKALK-DEDGWVRQSAAVALGQIG  113 (409)
T ss_dssp             ---GGGHHHHHHHTT-CSSHHHHHHHHHHHHHHT
T ss_pred             ---HhhHHHHHHHhc-CCCHHHHHHHHHHHHHHC
Confidence               123344445554 445566666666666554


No 245
>3TT9_A Plakophilin-2; CELL ADHESION; HET: GOL; 1.55A {Homo sapiens}
Probab=93.69  E-value=0.0017  Score=58.18  Aligned_cols=169  Identities=18%  Similarity=0.246  Sum_probs=122.4  Template_Neff=12.300

Q NP_000290.2     542 WLYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLS  620 (747)
Q Consensus       542 ~lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLs  620 (747)
                      .+++.|+++.|+.++. ..++.++..++++|.+++...+.     ....+.+.++++.|+.++. ..+..++..++++|.
T Consensus        47 ~~~~~~~i~~l~~~l~-~~~~~~~~~a~~~L~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~  120 (233)
T 3TT9_A           47 RVNQLRGILKLLQLLK-VQNEDVQRAVCGALRNLVFEDND-----NKLEVAELNGVPRLLQVLKQTRDLETKKQITGLLW  120 (233)
T ss_dssp             HHHHTTHHHHHHHGGG-CCCHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHHHHHHHCCCHHHHHHHHHHHH
T ss_pred             HHHHcchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCCc-----HHHHHHHcccHHHHHHHHhhCCCHHHHHHHHHHHH
Confidence            3467788999999998 46778889999999999874332     2444456789999999998 567889999999999


Q NP_000290.2     621 NMSRHPLL-HRVMGNQVFPEVTRLLTSHTGN---------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSM-LNNII  689 (747)
Q Consensus       621 nLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~---------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~gi-L~~Ll  689 (747)
                      +++..... ..+...+++..+..++......         ...+..++..++++|.+++...+.....+.+.+. ++.|+
T Consensus       121 ~l~~~~~~~~~~~~~~~~~~l~~ll~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~l~  200 (233)
T 3TT9_A          121 NLSSNDKLKNLMITEALLTLTENIIIPFSGWPEGDYPKANGLLDFDIFYNVTGCLRNMSSAGADGRKAMRRCDGLIDSLV  200 (233)
T ss_dssp             HHHTSGGGHHHHHHHHHHHHCCCCCHHHHCCCGGGCCCCCTTCCHHHHHHHHHHHHHHTTSCHHHHHHHHTSTTHHHHHH
T ss_pred             HHccCHHHHHHhhhhcHHHHHHHHHhhccCCCCCCCCcccCCCcHHHHHHHHHHHHHHHhcCHHHHHHHHHcccHHHHHH
Confidence            99876433 3334455666666665431000         0014677889999999999855666666776666 88888


Q NP_000290.2     690 NLCRSSA-----SPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       690 ~LL~s~~-----d~eVr~aAL~aLsnL~~~~~  716 (747)
                      .++....     ++.++..++++|.+|+...+
T Consensus       201 ~~l~~~~~~~~~~~~~~~~~~~~L~~l~~~~~  232 (233)
T 3TT9_A          201 HYVRGTIADYQPDDKATENCVCILHNLSYQLE  232 (233)
T ss_dssp             HHHHHHHHTTCTTCHHHHHHHHHHHHHCCCCC
T ss_pred             HHHHcccccCCCChHHHHHHHHHHHHhhhccc
Confidence            8887542     46788899999999887654


No 246
>3VWA_A Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; 2.2A {Saccharomyces cerevisiae}
Probab=93.63  E-value=0.0019  Score=68.57  Aligned_cols=152  Identities=11%  Similarity=0.067  Sum_probs=108.9  Template_Neff=10.600

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++++.++..+. +.++.++..++.+|..++...+.      . . ....+++.|..++.+.++.++..++.+|..++.
T Consensus       378 ~~~~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~ll~~l~~~l~d~~~~vR~~a~~~l~~i~~  448 (560)
T 3VWA_A          378 SSRIYPHFIQGLT-DSDATLRLQTLKTIPCIVSCLTE------R-Q-LNNELLRFLAKTQVDSDVEIRTWTVIIISKIST  448 (560)
T ss_dssp             CCCCHHHHHHGGG-CSSHHHHHHHHHHHHHHGGGCCH------H-C-CCCCCHHHHHHHTTCSSHHHHHHHHHHHHHHGG
T ss_pred             HhchHHHHHHHhc-CCCHHHHHHHHHHHHHHHhhCCH------H-H-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHH
Confidence            3457888888887 47788999999999988864321      1 1 235678888888888889999999999999987


Q NP_000290.2     625 HPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       625 ~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      .... .......+++.+...+.+      .++.++..|+.+|..++....  ...+ ...+++.+..++.+. +..++..
T Consensus       449 ~~~~~~~~~~~~l~~~l~~~l~d------~~~~vR~~a~~~l~~~~~~~~--~~~~-~~~ilp~l~~ll~d~-~~~VR~~  518 (560)
T 3VWA_A          449 ILSTSVGNRSNILATAFTKSLKD------PQVKPRLAALYGLEKSIELFD--VNTI-ANKILTVIAPGLLDK-SPIVRGR  518 (560)
T ss_dssp             GSSSCHHHHHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHTGGGSC--HHHC-CCCCHHHHGGGGGCS-SHHHHHH
T ss_pred             HhccchhhhHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHCC--HHHH-HHHHHHHHHHHHCCC-CHHHHHH
Confidence            6211 111223455666677765      378899999999999886422  1122 235688888888877 8899999


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      |+.+|..+...-
T Consensus       519 a~~~l~~i~~~l  530 (560)
T 3VWA_A          519 AKILFEEYLEKL  530 (560)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHH
Confidence            999988877543


No 247
>1XQR_A HspBP1 protein; armadillo repeat, superhelical twist, CHAPERONE; HET: MSE; 2.1A {Homo sapiens} SCOP: a.118.1.21
Probab=93.61  E-value=0.0019  Score=61.69  Aligned_cols=122  Identities=15%  Similarity=0.146  Sum_probs=77.8  Template_Neff=11.300

Q NP_000290.2     257 QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVD-LLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAV  335 (747)
Q Consensus       257 sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~-lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll  335 (747)
                      .++.++..++..|..++.. ......+...++++.++. ++...++.++..++.++.+++.........+...++++.+.
T Consensus        52 ~~~~~~~~al~~L~~l~~~-~~~~~~~~~~~~~~~l~~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~l~~~~~~~~l~  130 (296)
T 1XQR_A           52 ADQQEREGALELLADLCEN-MDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLL  130 (296)
T ss_dssp             HHHHHHHHHHHHHHHHHTS-HHHHHHHHHTTHHHHCCCCCTTCSSHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHHcC-HHHHHHHHHcccHHHHHHHHHhCCCHHHHHHHHHHHHHHhcCCHHHHHHHHhCCHHHHHH
Confidence            4456777788888887764 333334445566777777 77776778888999999998865443333344445777777


Q NP_000290.2     336 SLLRRTG-NAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       336 ~lL~ss~-d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .++. .. ++.++..++.++.+++..... ...+.. ++++.|+.++.
T Consensus       131 ~~l~-~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~i~~l~~~l~  177 (296)
T 1XQR_A          131 RLLD-RDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQ  177 (296)
T ss_dssp             HHHH-HCSCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHH
T ss_pred             HHHh-cCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhh
Confidence            7776 33 567788888888888764322 222222 45555555543


No 248
>1XQS_B HSPBP1 protein, Heat shock 70; armadillo repeat, superhelical twist, CHAPERONE; HET: AMP; 2.9A {Homo sapiens} SCOP: a.118.1.21
Probab=93.37  E-value=0.0023  Score=59.66  Aligned_cols=123  Identities=15%  Similarity=0.159  Sum_probs=77.3  Template_Neff=11.900

Q NP_000290.2     257 QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVD-LLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAV  335 (747)
Q Consensus       257 sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~-lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll  335 (747)
                      .+..++..++..|..++.. ......+...++++.++. ++...+..++..++.++..++.........+...++++.+.
T Consensus        36 ~~~~~~~~al~~L~~l~~~-~~~~~~~~~~~~i~~l~~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~  114 (280)
T 1XQS_B           36 ADQQEREGALELLADLCEN-MDNAADFCQLSGMHLLVGRYLEAGAAGLRWRAAQLIGTCSQNVAAIQEQVLGLGALRKLL  114 (280)
T ss_dssp             HHHHHHHHHHHHHHHHHTS-HHHHHHHHHTTHHHHCCCCCTSCSCHHHHHHHHHHHHHHHTTCHHHHHHHHTTTHHHHHH
T ss_pred             cCHHHHHHHHHHHHHHHhc-HHHHHHHHHcccHHHHHHHHhhcCCHHHHHHHHHHHHHHccCCHHHHHHHHHCCHHHHHH
Confidence            4466777888888888654 233334445567777777 77766778888899999998865443333444445777777


Q NP_000290.2     336 SLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       336 ~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      .++....++.++..++.++.+++..... ...+.. ++++.|+.++.
T Consensus       115 ~~l~~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~  161 (280)
T 1XQS_B          115 RLLDRDACDTVRVKALFAISCLVREQEAGLLQFLRLDGFSVLMRAMQ  161 (280)
T ss_dssp             HHHHSCSCHHHHHHHHHHHHHTTSSCHHHHHHHHTTTHHHHHHHHHT
T ss_pred             HHhccCCCHHHHHHHHHHHHHHHhcCHHHHHHHHHCCHHHHHHHHhh
Confidence            7775222566777888888888764322 222222 44555554443


No 249
>5VOZ_P V-type proton ATPase catalytic subunit; V-ATPase, SidK, rotational state 3;{Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=93.32  E-value=0.0027  Score=67.46  Aligned_cols=330  Identities=11%  Similarity=0.063  Sum_probs=181.1  Template_Neff=8.900

Q NP_000290.2     290 CKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTN---KLETR---RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       290 ~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~---~~~ll---~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      ..++.++.. .+.++...++.++..++...+ .   ...++   ..+.++.++.++. . ++.++..++.+|..++... 
T Consensus        78 ~~li~LL~~~~~~d~~~~~l~~l~~ll~~~~-~~~~r~~~~~~~~~~~~~~li~lL~-~-d~~i~~~a~~~L~~L~~~~-  153 (478)
T 5VOZ_P           78 IPLIHLLSTSDNEDCKKSVQNLIAELLSSDK-YGDDTVKFFQEDPKQLEQLFDVSLK-G-DFQTVLISGFNVVSLLVQN-  153 (478)
T ss_dssp             HHHHHHHHHCCCHHHHHHHHHHHHHHHHCSS-SCHHHHHHHHHCTHHHHHHTTSTTS-S-CHHHHHHHHHHHHHHHTSS-
T ss_pred             HHHHHHHccCCCHHHHHHHHHHHHHHHcCCC-CccchhHHhccChhhHHHHHHHHcC-C-CHHHHHHHHHHHHHHHHhc-
Confidence            556666654 466777788888888876544 3   22233   2456778888886 5 6677888888888887654 


Q NP_000290.2     363 LK-EELIA-DALPV--LADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD  438 (747)
Q Consensus       363 ~~-~~Lve-giLe~--Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  438 (747)
                      .. ..... ++++.  ++.+|.         ++      -++++-..|..||..-+.                     .+
T Consensus       154 ~~~~~~~~~~~l~~~~li~~L~---------~~------~~~~~~~~a~~~L~~L~~---------------------~~  197 (478)
T 5VOZ_P          154 GLHNVKLVEKLLKNNNLINILQ---------NI------EQMDTCYVCIRLLQELAV---------------------IP  197 (478)
T ss_dssp             SCCCHHHHHHHHSSHHHHHHHH---------CS------SCHHHHHHHHHHHHHHTT---------------------SH
T ss_pred             cccCcccchhhcccchHHHHHh---------cc------CCccHHHHHHHHHHHHcC---------------------Ch
Confidence            32 11122 66776  777761         11      123444555555533211                     11


Q NP_000290.2     439 AGRQTMRNY-SGLIDSLMAYVQNCVAA-----------SRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYT  506 (747)
Q Consensus       439 ~~~~~~~~~-~~~~~~~~~~~~~~~~~-----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  506 (747)
                      ..|...... .|.|..|...+.+....           ...+..-..++...|.+|++                      
T Consensus       198 ~~r~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~----------------------  255 (478)
T 5VOZ_P          198 EYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTF----------------------  255 (478)
T ss_dssp             HHHHHHHHSTTSSHHHHHHHHHHHHHSCSSCCCTTTSSSHHHHHHHHHHHHHHHHHTT----------------------
T ss_pred             HHHHHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhc----------------------
Confidence            122222221 34455555444432110           00111111222222233322                      


Q NP_000290.2     507 EKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHS--DAIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMS  583 (747)
Q Consensus       507 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~--G~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s  583 (747)
                                                   +......+.+.  ++++.|+.+++. .. +.++..++.+|.+++...+.  
T Consensus       256 -----------------------------~~~~~~~l~~~~~~~i~~Lv~ll~~-~~kekv~r~al~~L~nL~~~~~~--  303 (478)
T 5VOZ_P          256 -----------------------------NPVFANELVQKYLSDFLDLLKLVKI-TIKEKVSRLCISIILQCCSTRVK--  303 (478)
T ss_dssp             -----------------------------SHHHHHHHHHHSHHHHGGGHHHHHH-CCCHHHHHHHHHHHHHHTSTTST--
T ss_pred             -----------------------------CHHHHHHHHHHhHHHHHHHHHHHhc-cchHHHHHHHHHHHHHHhccChH--
Confidence                                         00111223444  789999999984 44 67888899999999875321  


Q NP_000290.2     584 SG-MSQLIGLKEKGLPQIARLLQSG---NSDVVRSGASLLSNMSRH-------P------------------------LL  628 (747)
Q Consensus       584 ~~-~~~~llie~giI~~Ll~LL~s~---d~eVr~~AL~aLsnLa~~-------~------------------------e~  628 (747)
                      .. .....+...+.+..++..|...   +++++..+..++..+...       +                        +.
T Consensus       304 ~~~~~~~~l~~~~~~l~ll~~L~~~~~~d~~l~~~l~~l~~~L~~~~~~lss~dey~~el~sg~l~wsp~h~s~~f~~~n  383 (478)
T 5VOZ_P          304 QHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDN  383 (478)
T ss_dssp             THHHHHHHCCCCCCHHHHHHHHTSCCCSCTHHHHHHHHHHHHHHHHHHTSCHHHHHHHHHHHTCCCCCTTTTCHHHHHHH
T ss_pred             hcHHHHHHHHHcCCHHHHHHHHHhCCCCcHHHHHHHHHHHHHHHHHHhhcCCHHHHHHHHHcCCCCCCCCcCCcChHHHh
Confidence            00 0012333444344566666543   444544433333333100       0                        01


Q NP_000290.2     629 -HRVM--GNQVFPEVTRLLTSHTGNT----SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       629 -~~ll--~~giI~~Ll~LL~s~s~~~----~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                       ..+.  ..++++.|+.+|.......    ..+..++..++..|++++...+.....+.+.++++.|+.++.+. ++.++
T Consensus       384 ~~~~~~~~~~~l~~Lv~lL~~~~~~~~~~~~~~~~v~~~a~~~l~~lv~~~~~~~~~l~~~g~~~~L~~Ll~~~-~~~vr  462 (478)
T 5VOZ_P          384 IDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHS-DSRVK  462 (478)
T ss_dssp             HHHHTTSSSHHHHHHHHHHHHHHHSSCSSSHHHHHHHHHHHHHHHHHHHHCTTTHHHHHHHTCHHHHHHHHTSS-CHHHH
T ss_pred             HHHhhhccHHHHHHHHHHHHhhhhCCCCCccccHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHhcCC-CHHHH
Confidence             0111  2457788888886510000    01244577788899999665566666677778899999999877 88999


Q NP_000290.2     702 EAARLLLSDMWSS  714 (747)
Q Consensus       702 ~aAL~aLsnL~~~  714 (747)
                      ..|+.++.+++.+
T Consensus       463 ~~Al~al~~l~~~  475 (478)
T 5VOZ_P          463 YEALKATQAIIGY  475 (478)
T ss_dssp             HHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhh
Confidence            9999999988754


No 250
>5D80_H V-type proton ATPase catalytic subunit; Hydrolase, Autoinhibition; 6.202A {Saccharomyces cerevisiae}
Probab=93.32  E-value=0.0027  Score=67.46  Aligned_cols=330  Identities=11%  Similarity=0.063  Sum_probs=181.1  Template_Neff=8.900

Q NP_000290.2     290 CKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTN---KLETR---RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDE  362 (747)
Q Consensus       290 ~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~---~~~ll---~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~  362 (747)
                      ..++.++.. .+.++...++.++..++...+ .   ...++   ..+.++.++.++. . ++.++..++.+|..++... 
T Consensus        78 ~~li~LL~~~~~~d~~~~~l~~l~~ll~~~~-~~~~r~~~~~~~~~~~~~~li~lL~-~-d~~i~~~a~~~L~~L~~~~-  153 (478)
T 5D80_H           78 IPLIHLLSTSDNEDCKKSVQNLIAELLSSDK-YGDDTVKFFQEDPKQLEQLFDVSLK-G-DFQTVLISGFNVVSLLVQN-  153 (478)
T ss_pred             HHHHHHHccCCCHHHHHHHHHHHHHHHcCCC-CccchhHHhccChhhHHHHHHHHcC-C-CHHHHHHHHHHHHHHHHhc-
Confidence            556666654 466777788888888876544 3   22233   2456778888886 5 6677888888888887654 


Q NP_000290.2     363 LK-EELIA-DALPV--LADRVIIPFSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSAD  438 (747)
Q Consensus       363 ~~-~~Lve-giLe~--Lv~LL~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  438 (747)
                      .. ..... ++++.  ++.+|.         ++      -++++-..|..||..-+.                     .+
T Consensus       154 ~~~~~~~~~~~l~~~~li~~L~---------~~------~~~~~~~~a~~~L~~L~~---------------------~~  197 (478)
T 5D80_H          154 GLHNVKLVEKLLKNNNLINILQ---------NI------EQMDTCYVCIRLLQELAV---------------------IP  197 (478)
T ss_pred             cccCcccchhhcccchHHHHHh---------cc------CCccHHHHHHHHHHHHcC---------------------Ch
Confidence            32 11122 66776  777761         11      123444555555533211                     11


Q NP_000290.2     439 AGRQTMRNY-SGLIDSLMAYVQNCVAA-----------SRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYT  506 (747)
Q Consensus       439 ~~~~~~~~~-~~~~~~~~~~~~~~~~~-----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  506 (747)
                      ..|...... .|.|..|...+.+....           ...+..-..++...|.+|++                      
T Consensus       198 ~~r~~~~~~~~g~i~~Lv~lL~~~~~~~~~~~~~~~~~~~~~~ql~~~a~~~L~~Ls~----------------------  255 (478)
T 5D80_H          198 EYRDVIWLHEKKFMPTLFKILQRATDSQLATRIVATNSNHLGIQLQYHSLLLIWLLTF----------------------  255 (478)
T ss_pred             HHHHHHHHccccchHHHHHHHHhccccccccccccccCcCcCHHHHHHHHHHHHHHhc----------------------
Confidence            122222221 34455555444432110           00111111222222233322                      


Q NP_000290.2     507 EKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGWLYHS--DAIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMS  583 (747)
Q Consensus       507 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~lve~--G~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s  583 (747)
                                                   +......+.+.  ++++.|+.+++. .. +.++..++.+|.+++...+.  
T Consensus       256 -----------------------------~~~~~~~l~~~~~~~i~~Lv~ll~~-~~kekv~r~al~~L~nL~~~~~~--  303 (478)
T 5D80_H          256 -----------------------------NPVFANELVQKYLSDFLDLLKLVKI-TIKEKVSRLCISIILQCCSTRVK--  303 (478)
T ss_pred             -----------------------------CHHHHHHHHHHhHHHHHHHHHHHhc-cchHHHHHHHHHHHHHHhccChH--
Confidence                                         00111223444  789999999984 44 67888899999999875321  


Q NP_000290.2     584 SG-MSQLIGLKEKGLPQIARLLQSG---NSDVVRSGASLLSNMSRH-------P------------------------LL  628 (747)
Q Consensus       584 ~~-~~~~llie~giI~~Ll~LL~s~---d~eVr~~AL~aLsnLa~~-------~------------------------e~  628 (747)
                      .. .....+...+.+..++..|...   +++++..+..++..+...       +                        +.
T Consensus       304 ~~~~~~~~l~~~~~~l~ll~~L~~~~~~d~~l~~~l~~l~~~L~~~~~~lss~dey~~el~sg~l~wsp~h~s~~f~~~n  383 (478)
T 5D80_H          304 QHKKVIKQLLLLGNALPTVQSLSERKYSDEELRQDISNLKEILENEYQELTSFDEYVAELDSKLLCWSPPHVDNGFWSDN  383 (478)
T ss_pred             hcHHHHHHHHHcCCHHHHHHHHHhCCCCcHHHHHHHHHHHHHHHHHHhhcCCHHHHHHHHHcCCCCCCCCcCCcChHHHh
Confidence            00 0012333444344566666543   444544433333333100       0                        01


Q NP_000290.2     629 -HRVM--GNQVFPEVTRLLTSHTGNT----SNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAA  701 (747)
Q Consensus       629 -~~ll--~~giI~~Ll~LL~s~s~~~----~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr  701 (747)
                       ..+.  ..++++.|+.+|.......    ..+..++..++..|++++...+.....+.+.++++.|+.++.+. ++.++
T Consensus       384 ~~~~~~~~~~~l~~Lv~lL~~~~~~~~~~~~~~~~v~~~a~~~l~~lv~~~~~~~~~l~~~g~~~~L~~Ll~~~-~~~vr  462 (478)
T 5D80_H          384 IDEFKKDNYKIFRQLIELLQAKVRNGDVNAKQEKIIIQVALNDITHVVELLPESIDVLDKTGGKADIMELLNHS-DSRVK  462 (478)
T ss_pred             HHHhhhccHHHHHHHHHHHHhhhhCCCCCccccHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHHHHHHHhcCC-CHHHH
Confidence             0111  2457788888886510000    01244577788899999665566666677778899999999877 88999


Q NP_000290.2     702 EAARLLLSDMWSS  714 (747)
Q Consensus       702 ~aAL~aLsnL~~~  714 (747)
                      ..|+.++.+++.+
T Consensus       463 ~~Al~al~~l~~~  475 (478)
T 5D80_H          463 YEALKATQAIIGY  475 (478)
T ss_pred             HHHHHHHHHHHhh
Confidence            9999999988754


No 251
>1F59_B IMPORTIN BETA-1/FXFG NUCLEOPORIN; Protein-protein complex, TRANSPORT PROTEIN RECEPTOR; 2.8A {Homo sapiens} SCOP: a.118.1.1
Probab=93.26  E-value=0.0024  Score=62.21  Aligned_cols=154  Identities=10%  Similarity=0.056  Sum_probs=84.6  Template_Neff=12.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM------------SSGMSQLIG---LKEKGLPQIARLLQSG------  607 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~------------s~~~~~~ll---ie~giI~~Ll~LL~s~------  607 (747)
                      ++.++.++. +.++.++..++.++..++......            .........   .-..+++.+...+...      
T Consensus       261 ~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~~~~  339 (442)
T 1F59_B          261 FAITIEAMK-SDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDDD  339 (442)
T ss_dssp             HHHHHHHHH-SSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGGTSCCSSCCCCHHHHHHHHHHHHHHHHTTCCCCCCCS
T ss_pred             HHHHHHHhc-CCcHHHHHHHHHHHHHHhhHHHHHHHHHHHHHhcCCCCchhhhHHHHHHHHHHHHHHHHHHccCCCCCCC
Confidence            455666666 356677777888887776531000            000000000   0122344444444332      


Q NP_000290.2     608 -NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSML  685 (747)
Q Consensus       608 -d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL  685 (747)
                       +..++..+..++..+......  .....+++.+...+.+      .++.++..++.++..+....+. ...... ..++
T Consensus       340 ~~~~~r~~a~~~l~~l~~~~~~--~~~~~~~~~l~~~l~~------~~~~~r~~al~~l~~l~~~~~~~~~~~~~-~~~~  410 (442)
T 1F59_B          340 DDWNPCKAAGVCLMLLATCCED--DIVPHVLPFIKEHIKN------PDWRYRDAAVMAFGCILEGPEPSQLKPLV-IQAM  410 (442)
T ss_dssp             SCCCHHHHHHHHHHHHHHHSTT--THHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHTSSSCHHHHHHHH-HTTH
T ss_pred             CCCcHHHHHHHHHHHHHHhccc--ccHHhHHHHHHHHhcC------CChHHHHHHHHHHHHHHhCCCHHHHHHHH-HHHH
Confidence             345667777777777654111  1112244445555544      3677888999999988865332 111111 2456


Q NP_000290.2     686 NNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       686 ~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +.+...+.+. ++.++..++++|..++.
T Consensus       411 ~~l~~~l~d~-~~~vr~~a~~~l~~l~~  437 (442)
T 1F59_B          411 PTLIELMKDP-SVVVRDTAAWTVGRICE  437 (442)
T ss_dssp             HHHHHHTTCS-CSHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcCC-CHHHHHHHHHHHHHHHH
Confidence            6677777665 78899999999988764


No 252
>6XTE_A Importin-5, antipain; human karyopherin, PA-PB1 sub-complex nuclear; HET: FC0, OAR; 2.27A {Homo sapiens}
Probab=93.23  E-value=0.0025  Score=70.44  Aligned_cols=153  Identities=9%  Similarity=0.114  Sum_probs=85.8  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. .
T Consensus       358 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  430 (1096)
T 6XTE_A          358 IKEHIMQMLQ-NPDWKYRHAGLMALSAIGEGCHQ-----QMEG-ILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFA  430 (1096)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHTHHHHTT-----TTTT-THHHHHHHHHHGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhhHH-----HHHH-HHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcc
Confidence            3444555555 35677788888888887764221     0111 1134566677777777888999999999998865 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINL--------CRSSA  696 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~L--------L~s~~  696 (747)
                      .. .......+++.+...+.+.     .+..++..++.+|..++...+. .....+ ..++..+...        +.+. 
T Consensus       431 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~-  503 (1096)
T 6XTE_A          431 PGFQKKFHEKVIAALLQTMEDQ-----GNQRVQAHAAAALINFTEDCPKSLLIPYL-DNLVKHLHSIMVLKLQELIQKG-  503 (1096)
T ss_dssp             THHHHHHHHHHHHHHHHHHHTC-----SCHHHHHHHHHHHHHHHHTSCHHHHGGGH-HHHHHHHHHHHHHHHHHHHHTC-
T ss_pred             HHHHHHHHHHHHHHHHHHhccc-----CCHHHHHHHHHHHHHHhccCCHHhHHHHH-HHHHHHHHHHHHHHHHHHHHcC-
Confidence            11 1111233555566655541     2467788888888888764322 111111 1223333322        2222 


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      +..++..++.++..++..
T Consensus       504 ~~~~~~~~~~~l~~l~~~  521 (1096)
T 6XTE_A          504 TKLVLEQVVTSIASVADT  521 (1096)
T ss_dssp             CCHHHHHHHHHHHHHHHH
T ss_pred             CHhHHHHHHHHHHHHHHH
Confidence            456677777777766643


No 253
>4HXT_A De Novo Protein OR329; Structural Genomics, PSI-Biology, Protein Structure; 1.95A {artificial gene}
Probab=93.20  E-value=0.0025  Score=56.21  Aligned_cols=134  Identities=25%  Similarity=0.298  Sum_probs=86.9  Template_Neff=13.200

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++.++.+++...+.....+...++++.+...+.+.++.++..++.++..++..........
T Consensus        87 ~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  166 (252)
T 4HXT_A           87 GVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAIVDAGGVEVLVKLLTSTDSEVQKEAARALANIASGPDEAIKAI  166 (252)
T ss_dssp             HHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTSCHHHHHHH
T ss_pred             hHHHHHHHccCCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhhCCCHHHHHHHHHHHHHHHcCCHHHHHHH
Confidence            44556666666677788888999988876543333333334567777777776677888889999988876543332333


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDEL-KEELIA-DALPVLADRVI  380 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~-~~~Lve-giLe~Lv~LL~  380 (747)
                      ...++++.+...+. ..++.++..++.++..++..... ...+.. ++++.+..++.
T Consensus       167 ~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~  222 (252)
T 4HXT_A          167 VDAGGVEVLVKLLT-STDSEVQKEAARALANIASGPTSAIKAIVDAGGVEVLQKLLT  222 (252)
T ss_dssp             HHTTHHHHHHHHTT-CSCHHHHHHHHHHHHHHTTSBHHHHHHHHHTTHHHHHHHGGG
T ss_pred             HHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhc
Confidence            33456777777776 55677888889999888864322 222223 56666666654


No 254
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=93.19  E-value=0.0029  Score=75.01  Aligned_cols=153  Identities=10%  Similarity=0.044  Sum_probs=93.2  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|...+. +.+..++..++.+|..++.....   . .... ....++..|...+.+.++.++..++.+|..++....
T Consensus       932 l~~~L~~~L~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~ 1005 (1304)
T 5IFE_C          932 ICGTVLWRLN-NKSAKVRQQAADLISRTAVVMKT---C-QEEK-LMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIG 1005 (1304)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhccC---c-CHHH-HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhC
Confidence            4566666676 46678888999999988754221   0 0011 123456677777777777888888888888876521


Q NP_000290.2     628 L---HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       628 ~---~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .   ...+ ..+++.|..++.+      .+..++..++.+|..++...+.....-.-..++..++..+.+. +..++..+
T Consensus      1006 ~~~l~~~l-~~ll~~L~~~L~~------~~~~Vr~~ai~~L~~i~~~~~~~~~~~~~~~il~~Ll~~l~~~-~~~vr~~a 1077 (1304)
T 5IFE_C         1006 MHKMTPPI-KDLLPRLTPILKN------RHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAH-KKAIRRAT 1077 (1304)
T ss_pred             hHHhcccH-HhHHHHHHHHhCC------CCHHHHHHHHHHHHHHHhcCcccCCHHHHHhhHHHHHHHccCC-CHHHHHHH
Confidence            1   1112 2456666677665      3577888899999888764322111000012344455555544 66788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus      1078 ~~~L~~l~~~ 1087 (1304)
T 5IFE_C         1078 VNTFGYIAKA 1087 (1304)
T ss_pred             HHHHHHHHHH
Confidence            8888877653


No 255
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=93.19  E-value=0.0029  Score=75.01  Aligned_cols=153  Identities=10%  Similarity=0.044  Sum_probs=93.2  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|...+. +.+..++..++.+|..++.....   . .... ....++..|...+.+.++.++..++.+|..++....
T Consensus       932 l~~~L~~~L~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~ 1005 (1304)
T 6AHD_1          932 ICGTVLWRLN-NKSAKVRQQAADLISRTAVVMKT---C-QEEK-LMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIG 1005 (1304)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhccC---c-CHHH-HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhC
Confidence            4566666676 46678888999999988754221   0 0011 123456677777777777888888888888876521


Q NP_000290.2     628 L---HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       628 ~---~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .   ...+ ..+++.|..++.+      .+..++..++.+|..++...+.....-.-..++..++..+.+. +..++..+
T Consensus      1006 ~~~l~~~l-~~ll~~L~~~L~~------~~~~Vr~~ai~~L~~i~~~~~~~~~~~~~~~il~~Ll~~l~~~-~~~vr~~a 1077 (1304)
T 6AHD_1         1006 MHKMTPPI-KDLLPRLTPILKN------RHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAH-KKAIRRAT 1077 (1304)
T ss_pred             hHHhcccH-HhHHHHHHHHhCC------CCHHHHHHHHHHHHHHHhcCcccCCHHHHHhhHHHHHHHccCC-CHHHHHHH
Confidence            1   1112 2456666677665      3577888899999888764322111000012344455555544 66788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus      1078 ~~~L~~l~~~ 1087 (1304)
T 6AHD_1         1078 VNTFGYIAKA 1087 (1304)
T ss_pred             HHHHHHHHHH
Confidence            8888877653


No 256
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=93.12  E-value=0.0027  Score=64.56  Aligned_cols=146  Identities=10%  Similarity=-0.008  Sum_probs=87.6  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.++..+....++.++..++.+|..+.....       .    ....++.+...+.+.+..++..++.++..+.....
T Consensus       428 ~~~~l~~~l~~~~~~~vr~~a~~~l~~~~~~~~-------~----~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  496 (592)
T 6QH5_B          428 IIATLCENLDSLDEPDARAAMIWIVGEYAERID-------N----ADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKP  496 (592)
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHhCC-------C----hhhHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhCC
Confidence            556666666522456777788888887765311       0    13456667777777778899999999998876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      ..  +...+...+..++.+.     .++.++..+..++..+.... ......+. ..++.++..+.+. ++.++..++.+
T Consensus       497 ~~--~~~~l~~~l~~~~~~~-----~~~~vr~~a~~~l~~l~~~~-~~~~~~~~-~~~~~l~~~~~~~-~~~~~~~~~~~  566 (592)
T 6QH5_B          497 SE--TQELVQQVLSLATQDS-----DNPDLRDRGYIYWRLLSTDP-VTAKEVVL-SEKPLISEETDLI-EPTLLDELICH  566 (592)
T ss_pred             HH--hhhhhHHHHHHHcCCC-----CCHHHHHHHHHHHHHHhcCc-hhhHHHHH-hhHHHHHHHcCCC-CHHHHHHHHHH
Confidence            10  1111222222323331     25678888888888876542 21112221 2356666666555 67888888888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      |..+...
T Consensus       567 l~~l~~~  573 (592)
T 6QH5_B          567 IGSLASV  573 (592)
T ss_pred             HHHHHHH
Confidence            8877653


No 257
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=92.93  E-value=0.0031  Score=67.35  Aligned_cols=154  Identities=10%  Similarity=0.023  Sum_probs=91.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....   . .... ....+++.+...+.+.++.++..++.++..++....
T Consensus       480 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~~  553 (852)
T 6EN4_C          480 ICGTVLWRLN-NKSAKVRQQAADLISRTAVVMKT---C-QEEK-LMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIG  553 (852)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhChh---h-cCHH-HHHhHHHHHHHHccCCCHHHHHHHHHHHHHHHHhhC
Confidence            4556666666 46677888899999888764221   0 0001 123566777777777778888889999988876521


Q NP_000290.2     628 L--HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~--~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .  .......+++.+...+.+      .++.++..++.++..++...+...........+..++..+.+. +..++..++
T Consensus       554 ~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  626 (852)
T 6EN4_C          554 MHKMTPPIKDLLPRLTPILKN------RHEKVQENCIDLVGRIADRGAEYVSAREWMRICFELLELLKAH-KKAIRRATV  626 (852)
T ss_pred             chhchhhHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCHHHCCHHHHHhcHHHHHHHhcCC-CHHHHHHHH
Confidence            1  111112355666666655      3567888888888888764322111000012344455555444 566777777


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       627 ~~l~~l~~~  635 (852)
T 6EN4_C          627 NTFGYIAKA  635 (852)
T ss_pred             HHHHHHHHH
Confidence            777777643


No 258
>6SA6_A DARPin-Armadillo fusion A5; protein fusion, DARPin, Armadillo, shared; HET: EDO; 1.6A {synthetic construct}
Probab=92.89  E-value=0.0032  Score=61.05  Aligned_cols=112  Identities=26%  Similarity=0.312  Sum_probs=76.5  Template_Neff=12.400

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+...++.++..++.+|.+++.........+...++++.+..++...+..++..++.++..++.........+
T Consensus       284 ~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~~  363 (397)
T 6SA6_A          284 ALPALVQLLSSPNEQILQEALWTLGNIASGGNEQIQAVIDAGALPALVQLLSSPNEQILQEALWTLGNIASGGNEQKQAV  363 (397)
T ss_dssp             HHHHHHHHTTCSSHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHHTSCHHHHHHH
T ss_pred             hHHHHHHHhcCCcHHHHHHHHHHHHHHhcCcHHHHHHHHhcChHHHHHHHhcCCCHHHHHHHHHHHHHHhcCCHHHHHHH
Confidence            45556666666667788888888888876544333334445677788888877777888899999998886434333334


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ...++++.+..++. ..++.++..++.++..++
T Consensus       364 ~~~~~~~~l~~~l~-~~~~~v~~~a~~~l~~l~  395 (397)
T 6SA6_A          364 KEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ  395 (397)
T ss_dssp             HHTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHH
T ss_pred             HHcCchHHHHHHHh-cccHHHHHHHHHHHHHHh
Confidence            44456777777776 456677777887777665


No 259
>6FT5_A A3_A3; alphaRep, artificial protein, chimera, bidomain; HET: GOL, SO4; 1.94A {synthetic construct}
Probab=92.89  E-value=0.0032  Score=60.70  Aligned_cols=91  Identities=14%  Similarity=0.155  Sum_probs=53.6  Template_Neff=12.800

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ..++.+...+.+.+..++..++..+..+..           ...++.+...+.+.++.++..++..+..+..        
T Consensus        23 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~-----------~~~~~~l~~~l~~~~~~vr~~a~~~L~~~~~--------   83 (409)
T 6FT5_A           23 EKVEMYIKNLQDDSYYVRRAAAYALGKIGD-----------ERAVEPLIKALKDEDAWVRRAAADALGQIGD--------   83 (409)
T ss_pred             hHHHHHHHHhcCCCHHHHHHHHHHHHHhcC-----------cchHHHHHHHhcCCCHHHHHHHHHHHHHHcC--------
Confidence            445556666666667777777777766643           1234445555556666777777777766543        


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                         ...++.+...+. +.++.++..++.++..+.
T Consensus        84 ---~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  113 (409)
T 6FT5_A           84 ---ERAVEPLIKALK-DEDGWVRQSAAVALGQIG  113 (409)
T ss_pred             ---chhHHHHHHHhc-CCCHHHHHHHHHHHHhhC
Confidence               123344455554 445566666666666554


No 260
>3C5W_A PP2A A subunit, PP2A C; methylesterase, phosphatase, PP2A, HYDROLASE; 2.8A {Homo sapiens}
Probab=92.86  E-value=0.0032  Score=54.65  Aligned_cols=146  Identities=11%  Similarity=0.041  Sum_probs=96.0  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....       .. ....+++.+...+.+.++.++..++.++..+.....
T Consensus        86 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~~~~~~~~~r~~a~~~l~~l~~~~~  156 (232)
T 3C5W_A           86 LNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK-------EW-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCG  156 (232)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHCH-------HH-CCCCCHHHHHHGGGCSSHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHhCh-------hH-HHhcHHHHHHHHhCCCCHHHHHHHHHHHHHHHHHhC
Confidence            4566666776 46677888899998888764221       11 123566777777777778888899999988876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .. .....+++.+...+.+      .++.++..++.++..+....+.   ......+++.+..++.+. ++.++..++.+
T Consensus       157 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~~~~~-~~~vr~~a~~~  225 (232)
T 3C5W_A          157 QD-ITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQEA  225 (232)
T ss_dssp             HH-HHHHHTHHHHHHGGGC------SSHHHHHHHHHHHHHHGGGSCH---HHCCCCCHHHHHHHHTCS-SHHHHHHHHHH
T ss_pred             hh-ccHhcHHHHHHHHhCC------CcHHHHHHHHHHHHHHHHHcCc---hHHHHHHHHHHHHHHhcC-CHHHHHHHHHH
Confidence            11 1122355666666665      3678888999999988764221   112234566777777765 77889989888


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..++.
T Consensus       226 l~~l~~  231 (232)
T 3C5W_A          226 LTVLSL  231 (232)
T ss_dssp             HHHTTC
T ss_pred             HHHHhc
Confidence            887753


No 261
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=92.86  E-value=0.0033  Score=56.30  Aligned_cols=110  Identities=11%  Similarity=0.093  Sum_probs=66.6  Template_Neff=12.800

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..+.++.|+..+. +.++.++..++.+|..+......      . . ....+++.+...+.+.++.++..++.+|..+..
T Consensus        31 ~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~~~~  101 (258)
T 4LAC_A           31 SLYPIAVLIDELR-NEDVQLRLNSIKKLSTIALALGV------E-R-TRSELLPFIVELAEDAKWRVRLAIIEYMPLLAG  101 (258)
T ss_pred             cccHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHccCH------H-H-HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHH
Confidence            3456777788887 46778888888888888754221      1 1 123456667777777777888888888887765


Q NP_000290.2     625 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       625 ~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      .... ......+++.+..++.+      .++.++..++.+|..++.
T Consensus       102 ~~~~-~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~  140 (258)
T 4LAC_A          102 QLGV-EYFDEKLNSLCMAWLVD------HVYAIREAATSNLKKLVE  140 (258)
T ss_pred             hCCC-hHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            4111 00112234444455444      245666666666666654


No 262
>4FDD_A Transportin-1, RNA-binding protein FUS; HEAT repeats, Karyopherin, nuclear import; 2.3A {Homo sapiens}
Probab=92.57  E-value=0.0039  Score=65.83  Aligned_cols=150  Identities=10%  Similarity=0.046  Sum_probs=86.4  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... ....+++.+...+.+.++.++..++.++..++.. .
T Consensus       360 ~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~v~~~~~~~l~~~~~~~~  432 (852)
T 4FDD_A          360 ILPLLKELLF-HHEWVVKESGILVLGAIAEGCMQ-----GMIP-YLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVV  432 (852)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHTTTTTHH-----HHGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHTHHHHH
T ss_pred             HHHHHHHHHh-CCChHHHHHHHHHHHHHHHHHHH-----hhHH-hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhc
Confidence            3444555555 35667777888888888764321     1111 1234666777777777788889999999888764 1


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+      .++.++..++.++..++........... ..++..+...+.+. +..++..++
T Consensus       433 ~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~~~~~~~  504 (852)
T 4FDD_A          433 SQPPDTYLKPLMTELLKRILD------SNKRVQEAACSAFATLEEEACTELVPYL-AYILDTLVFAFSKY-QHKNLLILY  504 (852)
T ss_dssp             HSCTTTTHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHGGGGGGGH-HHHHHHHHHHHHHC-CHHHHHHHH
T ss_pred             CCCCCcchHHHHHHHHHHHHc------CCHHHHHHHHHHHHHHHHHHHHhhHHHH-HHHHHHHHHHhhcc-CHHHHHHHH
Confidence            11 011112344555555554      2567888888888888764322111111 23455555555544 445566666


Q NP_000290.2     706 LLLSDMW  712 (747)
Q Consensus       706 ~aLsnL~  712 (747)
                      .+|..++
T Consensus       505 ~~l~~l~  511 (852)
T 4FDD_A          505 DAIGTLA  511 (852)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            6666665


No 263
>5NR4_A CLIP-associating protein 2; Microtubules, TOG domain, Tubulin, Structural; 1.198A {Homo sapiens}
Probab=92.57  E-value=0.004  Score=54.44  Aligned_cols=148  Identities=8%  Similarity=0.066  Sum_probs=97.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... ....+++.+...+.+.+..++..++.++..++....
T Consensus        53 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  125 (230)
T 5NR4_A           53 TVDALTGWVG-SSNYRVSLMGLEILSAFVDRLST-----RFKS-YVAMVIVALIDRMGDAKDKVRDEAQTLILKLMDQVA  125 (230)
T ss_dssp             HHHHHHHHHH-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHhhH-----HHHH-HHHHHHHHHHHHhccCCHHHHHHHHHHHHHHHHcCC
Confidence            5566667776 46778888999999988764321     1111 123567777777777777888889999888875421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .    ...+++.+...+.+      .++.++..++.++..++........  ....+++.+...+.+. ++.++..++.+
T Consensus       126 ~----~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~-~~~vr~~a~~~  192 (230)
T 5NR4_A          126 P----PMYIWEQLASGFKH------KNFRSREGVCLCLIETLNIFGAQPL--VISKLIPHLCILFGDS-NSQVRDAAILA  192 (230)
T ss_dssp             C----HHHHHHHHGGGGGC------SCHHHHHHHHHHHHHHHHHHCSTTS--CHHHHHHHHHHHTTCS-SHHHHHHHHHH
T ss_pred             C----HHHHHHHHHhcCCC------CCHHHHHHHHHHHHHHHHHhCCCcc--cHHHHHHHHHHHHCCC-CHHHHHHHHHH
Confidence            1    11244555555554      3677888889998888764322211  1124567777777766 78899999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      +..+....
T Consensus       193 l~~l~~~~  200 (230)
T 5NR4_A          193 IVEIYRHV  200 (230)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            98887543


No 264
>3C5W_A PP2A A subunit, PP2A C; methylesterase, phosphatase, PP2A, HYDROLASE; 2.8A {Homo sapiens}
Probab=92.51  E-value=0.0041  Score=53.94  Aligned_cols=107  Identities=12%  Similarity=0.133  Sum_probs=62.9  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.++.++..++..|..+......      . . ....+++.+...+.+.++.++..++.++..++....
T Consensus         8 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~l~~~~~   78 (232)
T 3C5W_A            8 PIAVLIDELR-NEDVQLRLNSIKKLSTIALALGV------E-R-LSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLG   78 (232)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHTTHHHHHHHHCS------S-H-CCCCCHHHHHHHTTCSSHHHHHHHHTTHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCh------H-H-HHHhHHHHHHHHHhCCCHHHHHHHHHHHHHHHHhhC
Confidence            4566777776 46677888888888887754221      1 1 123556667777777777788888888887765411


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      .. .....+++.+...+.+      .++.++..++.++..++.
T Consensus        79 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~  114 (232)
T 3C5W_A           79 VE-FFDEKLNSLCMAWLVD------HVYAIREAATSNLKKLVE  114 (232)
T ss_dssp             GG-GTTTTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHH
T ss_pred             HH-HHHHHHHHHHHHHHhC------CCHHHHHHHHHHHHHHHH
Confidence            10 1111234444444444      245566666666666554


No 265
>6XU2_A Importin-5, antipain; human karyopherin, PA-PB1 sub-complex nuclear; HET: FC0, OAR; 2.834A {Homo sapiens}
Probab=92.50  E-value=0.0042  Score=68.79  Aligned_cols=152  Identities=9%  Similarity=0.112  Sum_probs=85.0  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. .
T Consensus       377 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  449 (1115)
T 6XU2_A          377 IKEHIMQMLQ-NPDWKYRHAGLMALSAIGEGCHQ-----QMEG-ILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFA  449 (1115)
T ss_dssp             HHHHHHHHHS-SSCSHHHHHHHHHHHHHHHHHHH-----HHTT-THHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhhHH-----HHHH-HHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcc
Confidence            3444555555 35677788888888887764221     0111 1134566677777777888999999999988865 1


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINL--------CRSSA  696 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~L--------L~s~~  696 (747)
                      .. .......+++.+...+.+.     .+..++..++.+|..++...+. .....+ ..++..+...        +.+. 
T Consensus       450 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~-  522 (1115)
T 6XU2_A          450 PGFQKKFHEKVIAALLQTMEDQ-----GNQRVQAHAAAALINFTEDCPKSLLIPYL-DNLVKHLHSIMVLKLQELIQKG-  522 (1115)
T ss_dssp             THHHHHHHHHHHHHHHHHHHTT-----CCHHHHHHHHHHHHHHHHTSCHHHHGGGH-HHHHHHHHHHHHHHHHHHHHTC-
T ss_pred             HHHHHHHHHHHHHHHHHHhccc-----CCHHHHHHHHHHHHHHhccCCHHhHHHHH-HHHHHHHHHHHHHHHHHHHHcC-
Confidence            11 1111223555566555431     2567788888888888764322 111111 1223333322        2222 


Q NP_000290.2     697 SPKAAEAARLLLSDMWS  713 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~  713 (747)
                      +..++..++.++..++.
T Consensus       523 ~~~~~~~~~~~l~~l~~  539 (1115)
T 6XU2_A          523 TKLVLEQVVTSIASVAD  539 (1115)
T ss_dssp             CCHHHHHHHHHHHHHHH
T ss_pred             CHhHHHHHHHHHHHHHH
Confidence            45566667777766654


No 266
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=92.46  E-value=0.0043  Score=55.46  Aligned_cols=146  Identities=11%  Similarity=0.041  Sum_probs=96.3  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+..++. +.++.++..++.+|..++.....       .. ....+++.+...+.+.+..++..++.++..+.....
T Consensus       112 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  182 (258)
T 4LAC_A          112 LNSLCMAWLV-DHVYAIREAATSNLKKLVEKFGK-------EW-AHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCG  182 (258)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHcCCh-------hH-HHHhHHHHHHHHcCCCCHHHHHHHHHHHHHHHHcCC
Confidence            4566666776 46678888899999888764221       11 234567777777777778889999999888876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .. .....+++.+...+.+      .++.++..++.+|..+......   ......+++.+..++.+. ++.++..++.+
T Consensus       183 ~~-~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~~  251 (258)
T 4LAC_A          183 QD-ITTKHMLPTVLRMAGD------PVANVRFNVAKSLQKIGPILDN---STLQSEVKPILEKLTQDQ-DVDVKYFAQEA  251 (258)
T ss_pred             CC-ccHhhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCc---chhHHHHHHHHHHHHCCC-CHHHHHHHHHH
Confidence            11 1122355666666665      3678888999999888754221   112234566677777765 77888899888


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..+..
T Consensus       252 l~~l~~  257 (258)
T 4LAC_A          252 LTVLSL  257 (258)
T ss_pred             HHHHHh
Confidence            887753


No 267
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=92.45  E-value=0.0043  Score=66.18  Aligned_cols=147  Identities=10%  Similarity=0.006  Sum_probs=89.0  Template_Neff=12.900

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.++..+. +.+..++..++.++..+....+.     ....+ -..+++.+...+.+.+..++..++.++..+....
T Consensus       675 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~  747 (852)
T 6EN4_C          675 TVLPALMNEYR-VPELNVQNGVLKSLSFLFEYIGE-----MGKDY-IYAVTPLLEDALMDRDLVHRQTASAVVQHMSLGV  747 (852)
T ss_pred             hHHHHHHHHhC-CCCHHHHHHHHHHHHHHHhhCch-----hhHHH-HHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHcC
Confidence            35666777776 46677888899999888764321     01111 1356667777777777778888877777776541


Q NP_000290.2     627 -LLH-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 -e~~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                       ... ......+++.+...+.+      .++.++..++.++..+......       ...++.+...+.+. ++.++..+
T Consensus       748 ~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~-------~~~~~~l~~~l~~~-~~~vr~~a  813 (852)
T 6EN4_C          748 YGFGCEDSLNHLLNYVWPNVFE------TSPHVIQAVMGALEGLRVAIGP-------CRMLQYCLQGLFHP-ARKVRDVY  813 (852)
T ss_pred             ccCCcHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhhCc-------cchHHHHHHHhCCC-cHHHHHHH
Confidence             110 00111233333333333      2567777888888777643211       23455566666655 77889999


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..+...
T Consensus       814 ~~~l~~l~~~  823 (852)
T 6EN4_C          814 WKIYNSIYIG  823 (852)
T ss_pred             HHHHHHHHhh
Confidence            9998888754


No 268
>1QBK_B STRUCTURE OF THE KARYOPHERIN BETA2-RAN; HEAT REPEATS, NUCLEAR TRANSPORT PROTEIN; HET: GNP; 3.0A {Homo sapiens} SCOP: a.118.1.1
Probab=92.44  E-value=0.0043  Score=66.06  Aligned_cols=151  Identities=10%  Similarity=0.047  Sum_probs=89.7  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... ....+++.+...+.+.++.++..++.++..++... 
T Consensus       398 ~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  470 (890)
T 1QBK_B          398 ILPLLKELLF-HHEWVVKESGILVLGAIAEGCMQ-----GMIP-YLPELIPHLIQCLSDKKALVRSITCWTLSRYAHWVV  470 (890)
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHhHh-----hhHh-hHHHHHHHHHHHhcCCChHHHHHHHHHHHHHHHHHc
Confidence            3445555555 35677888888888888764321     1111 12346677777777778889999999999887651 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+      .++.++..++.++..++........... ..+++.+...+.+. +..++..++
T Consensus       471 ~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~~~~~~~  542 (890)
T 1QBK_B          471 SQPPDTYLKPLMTELLKRILD------SNKRVQEAACSAFATLEEEACTELVPYL-AYILDTLVFAFSKY-QHKNLLILY  542 (890)
T ss_pred             CCCCchhhHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHHHHhhHHHH-HHHHHHHHHHhhcc-CHHHHHHHH
Confidence            11 111112345555555554      3567888889998888764322111111 23455555555544 455666666


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..++.
T Consensus       543 ~~l~~l~~  550 (890)
T 1QBK_B          543 DAIGTLAD  550 (890)
T ss_pred             HHHHHHHH
Confidence            77666654


No 269
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=92.43  E-value=0.0043  Score=62.06  Aligned_cols=145  Identities=10%  Similarity=0.022  Sum_probs=87.2  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+....++.++..++.+|..+.....       .    ....++.+...+.+.++.++..++.+|..+.....
T Consensus       415 ~~~~l~~~l~~~~~~~~r~~a~~~l~~~~~~~~-------~----~~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  483 (570)
T 6CRI_I          415 VIATLCENLDSLDEPEARAAMIWIVGEYAERID-------N----ADELLESFLEGFHDKSTQVQLQLLTAIVKLFLKKP  483 (570)
T ss_dssp             THHHHTSSCTTCCCHHHHHHHHHHHHHTTTTST-------T----HHHHHHHHTTSGGGSCSHHHHHHHHHHHHHHHHCT
T ss_pred             HHHHHHHchhhCCCHHHHHHHHHHHHHHHHhcc-------C----HHHHHHHHHHccCCCCHHHHHHHHHHHHHHHhcCc
Confidence            456666666522456777788888887765311       0    13456667777777778889999999988876521


Q NP_000290.2     628 LHRVMGNQVFPEVTRL-LTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~L-L~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      . . +.. .+..++.. +.+.     .+..++..+..++..+.... ......+ ...++.++..+.+. ++.++..++.
T Consensus       484 ~-~-~~~-~~~~~l~~~~~~~-----~~~~vr~~a~~~~~~l~~~~-~~~~~~~-~~~~~~l~~~l~~~-~~~~~~~~~~  552 (570)
T 6CRI_I          484 T-E-TQE-LVQQVLSLATQDS-----DNPDLRDRGYIYWRLLSTDP-VAAKEVV-LAEKPLISEETDLI-EPTLLDELIC  552 (570)
T ss_dssp             T-T-THH-HHHHHHCCCCCSC-----CCHHHHHHHHHHHHHHHHCH-HHHHHHT-SCCCCCCCCCCCCC-CHHHHHHHHS
T ss_pred             H-H-HHH-HHHHHHHHHhcCC-----CCchHHHHHHHHHHHhcCCh-HHHHHHH-HccCCCCCccccCC-chhHHHHHHH
Confidence            1 0 111 12222222 3321     15678888888888776542 2111222 23466666666655 6788888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|..++..
T Consensus       553 ~l~~l~~~  560 (570)
T 6CRI_I          553 YIGTLASV  560 (570)
T ss_dssp             CSSBHHHH
T ss_pred             HhhcHHHH
Confidence            88887754


No 270
>2RU4_B Armadillo Repeat Protein, N-terminal fragment; solenoid repeat, Armadillo repeat motif; NMR {synthetic construct}
Probab=92.41  E-value=0.0045  Score=45.28  Aligned_cols=71  Identities=30%  Similarity=0.361  Sum_probs=42.5  Template_Neff=12.400

Q NP_000290.2     287 GGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       287 ~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      ++++.+...+...+..++..+++++.+++.........+...+.+..+...+. ..++.++..++.++.+++
T Consensus        12 ~~~~~l~~~l~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~   82 (84)
T 2RU4_B           12 GALPALVQLLSSPNEQILQEALWALSNIASGGNEQKQAVKEAGALEKLEQLQS-HENEKIQKEAQEALEKLQ   82 (84)
T ss_dssp             TSHHHHHHHTTCSCHHHHHHHHHHHHHHHTCSSSTTHHHHHHTCHHHHHHHTT-SSCHHHHHHHHHHHHHHC
T ss_pred             CcHHHHHHHhcCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHhc-CCCHHHHHHHHHHHHHHh
Confidence            45555666666556677788888888877653332223333445555665554 345566666777766654


No 271
>4L7M_A Putative uncharacterized protein; HEAT-repeats, Hypothetical, UNKNOWN FUNCTION; HET: MSE, GOL; 2.002A {Thermococcus onnurineus}
Probab=92.32  E-value=0.0047  Score=55.57  Aligned_cols=75  Identities=17%  Similarity=0.187  Sum_probs=52.1  Template_Neff=12.800

Q NP_000290.2     545 HSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       545 e~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      +.+.++.+...+. +.++.++..++.+|..+......   . .... .....++.|...+.+.++.++..++.+|..+..
T Consensus        35 ~~~~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~  108 (269)
T 4L7M_A           35 DKRALFLILELAG-EDDETTRLRAFVALGEILKRADS---D-LRMM-VLERHLDVFINALSQENEKVTIKALRALGYLVK  108 (269)
T ss_dssp             CHHHHHHHHHHTT-SSCHHHHHHHHHHHHHHHTTSCH---H-HHHH-HHHHHHHHHHHTCCSSSHHHHHHHHHHHHHHHT
T ss_pred             CcchHHHHHHHhC-CCCHHHHHHHHHHHHHHHhcCCH---H-HHHH-HHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHh
Confidence            4467778888887 46778888999999888764211   0 0111 123567777888887788888889998888876


Q NP_000290.2     625 H  625 (747)
Q Consensus       625 ~  625 (747)
                      .
T Consensus       109 ~  109 (269)
T 4L7M_A          109 D  109 (269)
T ss_dssp             T
T ss_pred             c
Confidence            3


No 272
>5WBJ_A Regulatory-associated protein of TOR 1,Eukaryotic; Raptor, TOS, PROTEIN BINDING; 3.0A {Arabidopsis thaliana}
Probab=92.23  E-value=0.0059  Score=72.68  Aligned_cols=100  Identities=11%  Similarity=0.096  Sum_probs=68.1  Template_Neff=8.700

Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLH-----------  629 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~-----------  629 (747)
                      ++.++..++.+|..|+...+.     ........++++.|+.+|.+.+++++..++.+|++++......           
T Consensus       612 ~~~lr~~a~~~L~~L~~~~~~-----~~~~~~~~~~~~~L~~lL~~~~~~VRaaal~aL~~li~~~~~~~~~~~~~~~~~  686 (1287)
T 5WBJ_A          612 EPLFLQWLCLCLGKLWEDFME-----AQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDIGFDSNKSVVEDEFDD  686 (1287)
T ss_dssp             CHHHHHHHHHHHHHHHTTCHH-----HHHHHHHTTHHHHHGGGGGCSCHHHHHHHHHHHHHTCC------------CCCC
T ss_pred             CHHHHHHHHHHHHHHHhccHH-----HHHHHHHcCHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCccccccccCCCCCH
Confidence            456667788888888765432     1233345678889999999889999999999999998762110           


Q NP_000290.2     630 ---RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       630 ---~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                         ..+..+++..|..++.+      .++.++..++.+|++++..
T Consensus       687 ~~~~~~~~~i~~~l~~~~~D------~S~~VR~e~~~aLs~~~~~  725 (1287)
T 5WBJ_A          687 DEKIRAEDAIIKSLLDVVSD------GSPLVRAEVAVALARFAFG  725 (1287)
T ss_dssp             CHHHHHHHHHHHHHHTTTTC------SCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHccC------CCHHHHHHHHHHHHHHHHh
Confidence               00233455566666655      3678889999999888754


No 273
>5WBK_A Regulatory-associated protein of TOR 1,Ribosomal; Raptor, TOS, PROTEIN BINDING; 3.11A {Arabidopsis thaliana}
Probab=92.22  E-value=0.0059  Score=72.65  Aligned_cols=101  Identities=11%  Similarity=0.093  Sum_probs=68.3  Template_Neff=8.700

Q NP_000290.2     560 KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLH----------  629 (747)
Q Consensus       560 ~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~----------  629 (747)
                      .++.++..++.+|..|+...+.     ........++++.|+.+|.+.+++++..++.+|+.++......          
T Consensus       611 ~~~~lr~~a~~~L~~L~~~~~~-----~~~~~~~~~~~~~L~~lL~~~~~~VRaaal~AL~~li~~~~~~~~~~~~~~~~  685 (1287)
T 5WBK_A          611 PEPLFLQWLCLCLGKLWEDFME-----AQIMGREANAFEKLAPLLSEPQPEVRAAAVFALGTLLDIGFDSNKSVVEDEFD  685 (1287)
T ss_dssp             -CHHHHHHHHHHHHHHHTTCHH-----HHHHHHTTTHHHHHGGGGGCSCHHHHHHHHHHHHHHCC------------CCC
T ss_pred             CCHHHHHHHHHHHHHHHcccHH-----HHHHHHHCCHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCccccccccCCCCC
Confidence            3456677788888888765432     1233345678889999999888999999999999998762110          


Q NP_000290.2     630 ----RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       630 ----~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                          ..+..+++..|..++.+      .++.++..++.+|++++..
T Consensus       686 ~~~~~~~~~~i~~~l~~~~~D------~s~~VR~e~~~als~~~~~  725 (1287)
T 5WBK_A          686 DDEKIRAEDAIIKSLLDVVSD------GSPLVRAEVAVALARFAFG  725 (1287)
T ss_dssp             CCHHHHHHHHHHHHHHTTTTC------SCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHccC------CCHHHHHHHHHHHHHHHHh
Confidence                01233455566666655      3678888899999888754


No 274
>2QK2_A LP04448p; Mini spindles, Msps, XMAP215, Dis1; 2.1A {Drosophila melanogaster}
Probab=92.22  E-value=0.005  Score=54.55  Aligned_cols=145  Identities=9%  Similarity=0.135  Sum_probs=94.6  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      .++.+...+. +.++.++..++..|..+....+.     .... .-..+++.+...+ .+.++.++..++.+|..+... 
T Consensus        16 l~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~   88 (242)
T 2QK2_A           16 MPKDFYDKLE-EKKWTLRKESLEVLEKLLTDHPK-----LENG-EYGALVSALKKVITKDSNVVLVAMAGKCLALLAKGL   88 (242)
T ss_dssp             SCTTHHHHHT-CSSHHHHHHHHHHHHHHHHHCSS-----BCCC-CCHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHH
T ss_pred             CCHHHHHHHh-ccchHHHHHHHHHHHHHHhhCcc-----cccc-hHHHHHHHHHHHHccCcHHHHHHHHHHHHHHHHHHh
Confidence            4566777777 47788888999999988764321     1111 1134667777777 777788999999999988865 


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .... ..+++.+...+.+      .+..++..++.+|..+....+       ....++.+...+.+. ++.++..+
T Consensus        89 ~~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~-------~~~~~~~l~~~l~~~-~~~~r~~~  153 (242)
T 2QK2_A           89 AKRFSNYA-SACVPSLLEKFKE------KKPNVVTALREAIDAIYASTS-------LEAQQESIVESLSNK-NPSVKSET  153 (242)
T ss_dssp             GGGGHHHH-HHHHHHHHHGGGC------CCHHHHHHHHHHHHHHHTTSC-------HHHHHHHHHHHTTCS-CHHHHHHH
T ss_pred             hHhHHHHH-HhHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHcCC-------HHHHHHHHHHHHcCC-CHHHHHHH
Confidence            211 1111 2356666666665      356788888888888875421       112455566666655 67778888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       154 ~~~l~~l~~~  163 (242)
T 2QK2_A          154 ALFIARALTR  163 (242)
T ss_dssp             HHHHHHHHTT
T ss_pred             HHHHHHHHHh
Confidence            8887777653


No 275
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=92.21  E-value=0.005  Score=67.54  Aligned_cols=115  Identities=14%  Similarity=0.059  Sum_probs=64.9  Template_Neff=13.000

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLR-SPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~-s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .+++.+...+.+.++.++..++.++..+...............+++.+...+. +.+..++..++.++..++........
T Consensus       397 ~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~~~~  476 (1078)
T 3W3U_A          397 KILDMVIPLINDPHPRVQYGCCKVLGQISTAFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVAFSEFASKDIL  476 (1078)
T ss_dssp             HHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHHSSTTSCHHHHHHHHHHHHHHHTTCCHHHH
T ss_pred             HHHHHHHHHccCCCHHHHHHHHHHHHHHHHHccHHHHHHHHHHHHHHHHHHcCCCCCHHHHHHHHHHHHHHHHhCChhhh
Confidence            34444455555566778888888888876543221111111234555555555 34566777788888777654322111


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ......++..+...+. ..++.++..++.++..++..
T Consensus       477 ~~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  512 (1078)
T 3W3U_A          477 EPYLDSLLTNLLVLLQ-SNKLYVQEQALTTIAFIAEA  512 (1078)
T ss_dssp             GGGHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            1111245555666665 44567778888888877754


No 276
>2IW3_B ELONGATION FACTOR 3A; ACETYLATION, ATP-BINDING, ELONGATION FACTOR, PROTEIN; HET: MSE, ADP, SO4; 2.4A {SACCHAROMYCES CEREVISIAE}
Probab=92.03  E-value=0.0058  Score=68.10  Aligned_cols=148  Identities=16%  Similarity=0.128  Sum_probs=74.2  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|..++. +.+..++..|+.+|..++.....       ..  ....++.++..+.+.+.  ...++..+..+.....
T Consensus       176 i~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-------~~--~~~~~~~l~~~l~~~~~--~~~~~~~l~~~~~~~~  243 (986)
T 2IW3_B          176 LIPVLSETMW-DTKKEVKAAATAAMTKATETVDN-------KD--IERFIPSLIQCIADPTE--VPETVHLLGATTFVAE  243 (986)
T ss_dssp             HHHHHHHHTT-CSCHHHHHHHHHHHHHHGGGCCS-------ST--TGGGHHHHHHHHHCGGG--HHHHHHHHTTCCCCSC
T ss_pred             HHHHHHHhcC-cCCHHHHHHHHHHHHHHHHhcCc-------HH--HHHHHHHHHHHhcCccc--chHHHHHHHHchhhcc
Confidence            5566667776 45667777888888777653211       11  12344455555543322  2222323222222110


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-QYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ........+++.+...+.+      .++.++..++.++..++........ ......+++.|+.++.+..++.++..++.
T Consensus       244 ~~~~~~~~~l~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~i~~~l~~~l~d~~d~~vr~~a~~  317 (986)
T 2IW3_B          244 VTPATLSIMVPLLSRGLNE------RETGIKRKSAVIIDNMCKLVEDPQVIAPFLGKLLPGLKSNFATIADPEAREVTLR  317 (986)
T ss_dssp             CCHHHHHHHHHHHHHHHTS------SSHHHHHHHHHHHHHHHTTCCCHHHHHHHHTTTHHHHHHHHHHCCCHHHHHHHHH
T ss_pred             cCHHHHHhHHHHHHHhccc------ccccccHHHHHHHHHHHHHhcCHhHHHHHHHHHHHHHHHhhcCCCCHHHHHHHHH
Confidence            0000011245555555554      3567778888888877754211100 00112356666666665423677777777


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      +|..+..
T Consensus       318 ~l~~l~~  324 (986)
T 2IW3_B          318 ALKTLRR  324 (986)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            7777643


No 277
>4G3A_B CLIP-associating protein; TOG domain, HEAT repeat, MAP; HET: GOL; 1.994A {Drosophila melanogaster}
Probab=91.94  E-value=0.0059  Score=54.01  Aligned_cols=150  Identities=10%  Similarity=0.094  Sum_probs=93.1  Template_Neff=12.600

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.++..+. +.++.++..++..|..++.....   . .... ....+++.+...+.+.++.++..++.++..++...
T Consensus         7 ~~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~---~-~~~~-~~~~~~~~l~~~l~d~~~~v~~~a~~~l~~l~~~~   80 (237)
T 4G3A_B            7 SDLDGFIQQMP-KADMRVKVQLAEDLVTFLSDDTN---S-IVCT-DMGFLIDGLMPWLTGSHFKIAQKSLEAFSELIKRL   80 (237)
T ss_dssp             SSHHHHHHHST-TCCHHHHHHHHHHHHHHHHCTTS---C-CCCS-CHHHHHHHHGGGGSSSCHHHHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHhcC-cCCHHHHHHHHHHHHHHhhCCCC---C-cccc-cHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHh
Confidence            35666777777 46778888999999888764221   0 0111 12345677777777778889999999999988652


Q NP_000290.2     627 L-LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNII-NLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e-~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll-~LL~s~~d~eVr~aA  704 (747)
                      . ........+++.++..+.+      .+..++..++.+|..+........     ...++.+. .++.+. ++.++..+
T Consensus        81 ~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~~~~-----~~~~~~l~~~~l~~~-~~~~r~~a  148 (237)
T 4G3A_B           81 GSDFNAYTATVLPHVIDRLGD------SRDTVREKAQLLLRDLMEHRVLPP-----QALIDKLATSCFKHK-NAKVREEF  148 (237)
T ss_dssp             GGGGGGTHHHHHHHHHHHHTC------SCHHHHHHHHHHHHHHHHTTSSCH-----HHHHHHHHHHHTTCS-CHHHHHHH
T ss_pred             hhhHHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHcCCCCH-----HHHHHHHHHHHhhCC-CHHHHHHH
Confidence            1 1111112356666666655      356788888888888875311111     12345555 555544 56677777


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       149 ~~~l~~l~~~  158 (237)
T 4G3A_B          149 LQTIVNALHE  158 (237)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            7777776644


No 278
>5EWP_B Uncharacterized protein; translocation and attachment of rhoptries; 1.8A {Plasmodium falciparum Santa Lucia}
Probab=91.92  E-value=0.0062  Score=55.67  Aligned_cols=176  Identities=16%  Similarity=0.152  Sum_probs=134.6  Template_Neff=11.800

Q NP_000290.2     528 CPLPEEETNPKGSGWLYHSDAIRTYLNLMGKSKKDAT----------------LEACAGALQNLTASK--GLMSSGMSQL  589 (747)
Q Consensus       528 ~~~~~~~~ni~~~~~lve~G~I~~LL~LL~ss~d~eV----------------r~~AL~aL~nLs~~s--~~~s~~~~~~  589 (747)
                      +-+++++++++.+..+++.|+++.|+.+|.. .+...                +..++++|.+++...  +.     ...
T Consensus         7 ~~~~~~~~~~~~~~~~~~~g~i~~L~~ll~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~-----~~~   80 (252)
T 5EWP_B            7 KLLSFTSNDILRFDKAYDENDVQEFVNLCSS-TCEIEKLEDRMHPWAADPKTIGALSATQLAILASKENEPH-----YKD   80 (252)
T ss_dssp             --CCCCCHHHHHHHHHHHTTCHHHHHHHTTC-CCBCCCC--CCCSSSCCCCBHHHHHHHHHHHHHTCTTCTH-----HHH
T ss_pred             HHHhccHHHHhhhHHHHhcCCHHHHHHHhcC-CChHHHHHHHhhhhhCCHHHHHHHHHHHHHHHhcCCCCHH-----HHH
Confidence            4456899999999999999999999999983 33222                236888888888652  21     244


Q NP_000290.2     590 IGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRN  667 (747)
Q Consensus       590 llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsn  667 (747)
                      .+.+.++++.|+.++...++.++..++++|.+++.. ... ..+...++++.++.++..      .++.++..++++|.+
T Consensus        81 ~~~~~g~i~~l~~~l~~~~~~~~~~a~~~L~~l~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~  154 (252)
T 5EWP_B           81 AIREANGIAVFINLLKSHELDRVHAAVVALSFLSVDNVKNCICMFESGALPYLISGMKS------NIDGMKAACAQTCRN  154 (252)
T ss_dssp             HHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTTCHHHHHHHHHTTCHHHHHHHTTC------SCHHHHHHHHHHHHH
T ss_pred             HHHHcccHHHHHHHhhCCCHHHHHHHHHHHHHHhCCCHHHHHHHHHCCcHHHHHHHhhC------CCHHHHHHHHHHHHH
Confidence            445778999999999888888999999999999986 443 344556788888888875      367889999999999


Q NP_000290.2     668 LMASQPQLAKQYFSSSMLNNIINLCRSSASP-------KAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       668 La~~s~e~~~~Lve~giL~~Ll~LL~s~~d~-------eVr~aAL~aLsnL~~~~~  716 (747)
                      ++...+.....+.+.++++.|+.++... +.       .++..++.+|.+++...+
T Consensus       155 l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~~~~~~a~~~l~~l~~~~~  209 (252)
T 5EWP_B          155 IFVLDKKYKKEFLKLGGITQLVNLLELP-SNYDDSQPLYTQLEAIYHLEDFILNDG  209 (252)
T ss_dssp             HHTTCHHHHHHHHHTTHHHHHHHTTSCC-TTCCSCSCCHHHHHHHHHHHHHHEETT
T ss_pred             HHhcCHHHHHHHHHCChHHHHHHHhcCC-CCCCCCchHHHHHHHHHHHHHHHhcCC
Confidence            9875455666677778889999988765 33       378889999999987665


No 279
>4QMI_B Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG domain; 1.9A {Homo sapiens}
Probab=91.92  E-value=0.006  Score=54.09  Aligned_cols=147  Identities=7%  Similarity=-0.004  Sum_probs=97.2  Template_Neff=12.600

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .....++.++..+.+.+..++..++.++..+.....
T Consensus        60 ~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  132 (240)
T 4QMI_B           60 LPTALKGRLN-DSNKILVQQTLNILQQLAVAMGP-----NIKQ-HVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG  132 (240)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GCCCCCHHHHHHTTCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhcH-----HHHH-HHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC
Confidence            4566666676 46778888999999988764321     1111 123466777777777778888889999888875421


Q NP_000290.2     628 LHRVMGNQVF--PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI--~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .     ..++  +.+...+.+      .++.++..++.+|..++...... ... -..+++.+...+.+. +..++..++
T Consensus       133 ~-----~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~-~~~-~~~~~~~l~~~l~~~-~~~vr~~a~  198 (240)
T 4QMI_B          133 M-----KEWLEGEDLSEELKK------ENPFLRQELLGWLAEKLPTLRST-PTD-LILCVPHLYSCLEDR-NGDVRKKAQ  198 (240)
T ss_dssp             S-----HHHHSSSHHHHHHTS------CCHHHHHHHHHHHHHHGGGCSSC-CGG-GGGGHHHHHHHTTCS-SHHHHHHHH
T ss_pred             h-----hHhccHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhCCCC-cHH-HHHHHHHHHHHHhcC-CHHHHHHHH
Confidence            1     1234  555666655      36788888999998877543221 111 124567777777766 788999999


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..+....
T Consensus       199 ~~l~~l~~~~  208 (240)
T 4QMI_B          199 DALPFFMMHL  208 (240)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHh
Confidence            9998887653


No 280
>4QMJ_A Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG DOMAIN; 2.498A {Homo sapiens}
Probab=91.92  E-value=0.006  Score=54.09  Aligned_cols=147  Identities=7%  Similarity=-0.004  Sum_probs=97.2  Template_Neff=12.600

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .....++.++..+.+.+..++..++.++..+.....
T Consensus        60 ~~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  132 (240)
T 4QMJ_A           60 LPTALKGRLN-DSNKILVQQTLNILQQLAVAMGP-----NIKQ-HVKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG  132 (240)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GCCCCCHHHHHGGGCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhcH-----HHHH-HHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC
Confidence            4566666676 46778888999999988764321     1111 123466777777777778888889999888875421


Q NP_000290.2     628 LHRVMGNQVF--PEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI--~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .     ..++  +.+...+.+      .++.++..++.+|..++...... ... -..+++.+...+.+. +..++..++
T Consensus       133 ~-----~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~-~~~-~~~~~~~l~~~l~~~-~~~vr~~a~  198 (240)
T 4QMJ_A          133 M-----KEWLEGEDLSEELKK------ENPFLRQELLGWLAEKLPTLRST-PTD-LILCVPHLYSCLEDR-NGDVRKKAQ  198 (240)
T ss_dssp             S-----HHHHSSSHHHHHHHS------SCHHHHHHHHHHHHHHGGGCSCC-CGG-GGGGHHHHHHHTTCS-SHHHHHHHH
T ss_pred             h-----hHhccHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhCCCC-cHH-HHHHHHHHHHHHhcC-CHHHHHHHH
Confidence            1     1234  555666655      36788888999998877543221 111 124567777777766 788999999


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..+....
T Consensus       199 ~~l~~l~~~~  208 (240)
T 4QMJ_A          199 DALPFFMMHL  208 (240)
T ss_dssp             HTHHHHHHHH
T ss_pred             HHHHHHHHHh
Confidence            9998887653


No 281
>5XAH_A Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=91.84  E-value=0.0062  Score=58.52  Aligned_cols=153  Identities=14%  Similarity=0.074  Sum_probs=87.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +++.+...+. +.++.++..++.+|..++.....     ....+ -..+++.+...+. +.++.++..++.++..++...
T Consensus       235 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~i~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_A          235 LLPVLLSTAQ-EADPEVRSNAIFGMGVLAEHGGH-----PAQEH-FPKLLGLLFPLLARERHDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHHHHTS-CSSHHHHHHHHHHHHHHHHHHHH-----HHHTT-HHHHHHHHTTHHHHCCCHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhh-cCCHHHHHHHHHHHHHHHHhcCc-----hHHhh-HHHHHHHHHHHhccCCCHHHHHHHHHHHHHHHHhC
Confidence            4556666666 35677888888888888764321     11111 1346677777777 567788999999999888652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA-SPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~-d~eVr~aAL  705 (747)
                      .... ....+++.+...+...    ......+. ++.++..+....+......+ ..+++.+...+.+.. ...++..++
T Consensus       308 ~~~~-~~~~~~~~l~~~l~~~----~~~~~~~~-~~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~~~~~~r~~~~  380 (416)
T 5XAH_A          308 PTRK-PEPQVLAALLHALPLK----EDLEEWVT-IGRLFSFLYQSSPDQVIDVA-PELLRICSLILADNKIPPDTKAALL  380 (416)
T ss_dssp             CSSC-CCHHHHHHHHHHCSCC----SCTTHHHH-HHHHHHHHHHHCSTTGGGSH-HHHHHTGGGTSSCTTSCHHHHHHHH
T ss_pred             CCCC-CHHHHHHHHHHhCCCC----CchhhHHH-HHHHHHHHHhcCchHHHhhH-HHHHHHHHHHHcCCCCCHHHHHHHH
Confidence            1110 1123455555555221    01344555 77777777764332211111 134555666555431 235778888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       381 ~~l~~l~~~  389 (416)
T 5XAH_A          381 LLLTFLAKQ  389 (416)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHh
Confidence            888877643


No 282
>5XAH_C Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=91.84  E-value=0.0062  Score=58.52  Aligned_cols=153  Identities=14%  Similarity=0.074  Sum_probs=87.3  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +++.+...+. +.++.++..++.+|..++.....     ....+ -..+++.+...+. +.++.++..++.++..++...
T Consensus       235 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~i~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_C          235 LLPVLLSTAQ-EADPEVRSNAIFGMGVLAEHGGH-----PAQEH-FPKLLGLLFPLLARERHDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHSHH-----HHHTT-HHHHHHHHTHHHHHCCCHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHhh-cCCHHHHHHHHHHHHHHHHhcCc-----hHHhh-HHHHHHHHHHHhccCCCHHHHHHHHHHHHHHHHhC
Confidence            4556666666 35677888888888888764321     11111 1346677777777 567788999999999888652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA-SPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~-d~eVr~aAL  705 (747)
                      .... ....+++.+...+...    ......+. ++.++..+....+......+ ..+++.+...+.+.. ...++..++
T Consensus       308 ~~~~-~~~~~~~~l~~~l~~~----~~~~~~~~-~~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~~~~~~r~~~~  380 (416)
T 5XAH_C          308 PTRK-PEPQVLAALLHALPLK----EDLEEWVT-IGRLFSFLYQSSPDQVIDVA-PELLRICSLILADNKIPPDTKAALL  380 (416)
T ss_dssp             CC---CCHHHHHHHHHHCSCC----SCGGGHHH-HHHHHHHHHHHCHHHHTTTH-HHHHHHHHHHHSCTTSCHHHHHHHH
T ss_pred             CCCC-CHHHHHHHHHHhCCCC----CchhhHHH-HHHHHHHHHhcCchHHHhhH-HHHHHHHHHHHcCCCCCHHHHHHHH
Confidence            1110 1123455555555221    01344555 77777777764332211111 134555666555431 235778888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       381 ~~l~~l~~~  389 (416)
T 5XAH_C          381 LLLTFLAKQ  389 (416)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHh
Confidence            888877643


No 283
>2QK1_A Protein STU2; stu2, Stu2p, XMAP215, Dis1, TOG; 1.7A {Saccharomyces cerevisiae}
Probab=91.81  E-value=0.0063  Score=53.79  Aligned_cols=152  Identities=9%  Similarity=0.052  Sum_probs=95.7  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQN-LTASKGLMSSGMSQ--LIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~n-Ls~~s~~~s~~~~~--~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa  623 (747)
                      .++.+...+. +.++.++..++..|.. ++.....     ..  .. ....+++.+...+ .+.++.++..++.++..++
T Consensus        17 l~~~l~~~l~-~~~~~~r~~a~~~l~~~l~~~~~~-----~~~~~~-~~~~~~~~l~~~l~~d~~~~vr~~a~~~l~~l~   89 (249)
T 2QK1_A           17 LPKDFQERIT-SSKWKDRVEALEEFWDSVLSQTKK-----LKSTSQ-NYSNLLGIYGHIIQKDANIQAVALAAQSVELIC   89 (249)
T ss_dssp             SCTTHHHHHT-CSSHHHHHHHHHHHHHHTGGGCCC-----BCCTTC-CCHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHH
T ss_pred             CCHHHHHHHh-CCCHHHHHHHHHHHHHHHHhcCCC-----cCCCCc-cHHHHHHHHHHHHhhCcHHHHHHHHHHHHHHHH
Confidence            4556666676 4677888899999998 7754221     01  01 1245677777888 7778889999999999888


Q NP_000290.2     624 RH-PL-LHR-VMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-AKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       624 ~~-~e-~~~-ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      .. .. ... .....+++.++..+.+      .+..++..++.++..+....+.. ..... ..+++.+...+.+. ++.
T Consensus        90 ~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~  161 (249)
T 2QK1_A           90 DKLKTPGFSKDYVSLVFTPLLDRTKE------KKPSVIEAIRKALLTICKYYDPLASSGRN-EDMLKDILEHMKHK-TPQ  161 (249)
T ss_dssp             HHHCTTTSCHHHHHHHHHHHHHGGGC------CCHHHHHHHHHHHHHHHHHSCTTCTTCTT-HHHHHHHHHHTTCS-SHH
T ss_pred             HHcCCCCCCHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhChhcccCCH-HHHHHHHHHHhCCC-CHH
Confidence            65 22 111 1122355666666655      35678888888888887542210 00111 23566666666655 677


Q NP_000290.2     700 AAEAARLLLSDMWSS  714 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~  714 (747)
                      ++..++.++..+...
T Consensus       162 vr~~~~~~l~~~~~~  176 (249)
T 2QK1_A          162 IRMECTQLFNASMKE  176 (249)
T ss_dssp             HHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh
Confidence            888888888777654


No 284
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=91.79  E-value=0.0063  Score=66.66  Aligned_cols=114  Identities=16%  Similarity=0.088  Sum_probs=64.4  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS-PNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s-~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      +++.+...+.+.++.++..++.++..+...............+++.+...+.+ .+..++..++.++..++.........
T Consensus       398 ~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~~~~~  477 (1078)
T 5H2V_A          398 ILDMVIPLINDPHPRVQYGCCNVLGQISTDFSPFIQRTAHDRILPALISKLTSECTSRVQTHAAAALVNFSEFASKDILE  477 (1078)
T ss_dssp             HHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTTTHHHHHHHHHHHHHHHHTTSTTSCHHHHHHHHHHHHHHHTTCCHHHHG
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHhhccHHHHHHHHHhHHHHHHHHcccCCCHHHHHHHHHHHHHHHhcCChhhHH
Confidence            34444445555566778888888887765432211101113455555555554 45677788888888777543221101


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....++..+...+. ..++.++..++.++..++..
T Consensus       478 ~~~~~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~  512 (1078)
T 5H2V_A          478 PYLDSLLTNLLVLLQ-SNKLYVQEQALTTIAFIAEA  512 (1078)
T ss_dssp             GGHHHHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHH
Confidence            111245555666654 44566778888888877654


No 285
>6OWT_A AP-2 complex subunit alpha, AP-2; AP, HIV, Nef, trafficking, Protein;{Rattus norvegicus}
Probab=91.69  E-value=0.0072  Score=67.72  Aligned_cols=142  Identities=13%  Similarity=0.056  Sum_probs=80.2  Template_Neff=11.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSD--VVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~e--Vr~~AL~aLsnLa~~  625 (747)
                      .++.++.++. +.+..++..++.++..+......          ....+++.+...+.+.+..  ++..++++|+.+...
T Consensus       442 ~~~~l~~~l~-~~~~~v~~~a~~~l~~i~~~~~~----------~~~~~~~~l~~~l~~~~~~~~v~~~a~~~L~~~~~~  510 (939)
T 6OWT_A          442 YVDTILNLIR-IAGDYVSEEVWYRVIQIVINRDD----------VQGYAAKTVFEALQAPACHENLVKVGGYILGEFGNL  510 (939)
T ss_pred             HHHHHHHHhC-CCChhcCHHHHHHHHHHHhcCHH----------HHHhHHHHHHHHhcCCCCcHHHHHHHHHHHHHHHHh
Confidence            5666777776 35556777777777776643211          1234556666667654444  778888888877654


Q NP_000290.2     626 P-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC---RSSASPKAA  701 (747)
Q Consensus       626 ~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL---~s~~d~eVr  701 (747)
                      . .........++..|...+..      .+..++..++.+|..++...+..      ...+..++..+   .+. +.+++
T Consensus       511 ~~~~~~~~~~~~~~~L~~~l~~------~~~~vr~~al~aL~~l~~~~~~~------~~~i~~ll~~l~~~~~~-d~evr  577 (939)
T 6OWT_A          511 IAGDPRSSPLIQFNLLHSKFHL------CSVPTRALLLSTYIKFVNLFPEV------KATIQDVLRSDSQLKNA-DVELQ  577 (939)
T ss_pred             cCCCCCCCHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhChhh------HhHHHHHHHHhcccCCC-CHHHH
Confidence            1 11100111244455555554      25677888888888887643221      12334444433   333 66777


Q NP_000290.2     702 EAARLLLSDMWS  713 (747)
Q Consensus       702 ~aAL~aLsnL~~  713 (747)
                      ..++.++..+..
T Consensus       578 ~~a~~~l~~l~~  589 (939)
T 6OWT_A          578 QRAVEYLRLSTV  589 (939)
T ss_pred             HHHHHHHHHHcC
Confidence            777777766553


No 286
>2P8Q_A Importin beta-1 subunit, Snurportin-1; HEAT repeat, IBB-domain, Importin, Karyopherin; 2.35A {Homo sapiens} SCOP: a.118.1.1
Probab=91.69  E-value=0.0066  Score=64.52  Aligned_cols=160  Identities=8%  Similarity=0.007  Sum_probs=89.0  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.++..+..+.++.++..++.+|..++.....     ....+ -..+++.+...+.+.  ++.++..++.++..++..
T Consensus       650 ~~~~l~~~l~~~~~~~vr~~~~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~~v~~~a~~~l~~l~~~  723 (876)
T 2P8Q_A          650 FKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQS-----NIIPF-CDEVMQLLLENLGNENVHRSVKPQILSVFGDIALA  723 (876)
T ss_dssp             HHHHHHHHHHCCSSHHHHHHHHHHHHHHHHHHGG-----GGHHH-HHHHHHHHHHHTSCSSSCTTHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHhccccHHHHHHHHHHHHHHHHHHhh-----cchHh-HHHHHHHHHHHHcCcCcccchHhHHHHHHHHHHHH
Confidence            3455555555225667888888888888754221     01111 135677777777766  678888999999888865


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTG-----NTSNSEDILSSACYTVRNLMASQPQLAKQYFS-----SSMLNNIINLCR  693 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~-----~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve-----~giL~~Ll~LL~  693 (747)
                       ... ..++ ..+++.+...+.....     ....+..++..++.++..++.........+..     ...++.++..+.
T Consensus       724 ~~~~~~~~~-~~~~~~l~~~l~~~~~~~~~~~~~~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~  802 (876)
T 2P8Q_A          724 IGGEFKKYL-EVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFID  802 (876)
T ss_dssp             HGGGGHHHH-HHHHHHHHHHHSCCCCTTCSTTHHHHHHHHHHHHHHHHHHHHHHSCSSCSCCCGGGGTGGGHHHHHHHHH
T ss_pred             hchhhHHHH-HHHHHHHHHHHHccCCCCchHHHHHHHHHHHHHHHHHHHHHHHHhcCcccCCCchhhHHHhHHHHHHHHH
Confidence             211 1111 2345555555443100     00014667888888888887621111111100     011444444443


Q NP_000290.2     694 ------SSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       694 ------s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                            +. +..++..++.++..++..-
T Consensus       803 ~~~~~~~~-~~~v~~~~~~~l~~l~~~~  829 (876)
T 2P8Q_A          803 HIAGDEDH-TDGVVACAAGLIGDLCTAF  829 (876)
T ss_dssp             HHHHSSCC-CHHHHHHHHHHHHHHHHHH
T ss_pred             HHhCCCCC-ChhHHHHHHHHHHHHHHHh
Confidence                  33 5778888888888877543


No 287
>5MFO_F YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: CA, EDO; 1.3A {synthetic construct}
Probab=91.65  E-value=0.0068  Score=51.30  Aligned_cols=157  Identities=18%  Similarity=0.285  Sum_probs=121.2  Template_Neff=13.100

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .+.++.++..+. +.++.++..++..|.+++...+.     ....+.+.++++.|..++.+.++.++..++++|.+++..
T Consensus         3 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~   76 (202)
T 5MFO_F            3 GSELPQMVQQLN-SPDQQELQSALRKLSQIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASG   76 (202)
T ss_dssp             CTTHHHHHHHTT-CSCHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTS
T ss_pred             CchHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChH-----HHHHHHHCChHHHHHHHhcCCCHHHHHHHHHHHHHHhcC
Confidence            456788888887 47778888999999999875332     233445678899999999988889999999999999976


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                       ... ..+...++++.+..++.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. +..++..
T Consensus        77 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~  149 (202)
T 5MFO_F           77 GNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSP-NEQILQE  149 (202)
T ss_dssp             CHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHH
T ss_pred             CHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHH
Confidence             333 334455678888888866      3678888999999999876455555556667888888888866 7888999


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      ++.+|.+++...
T Consensus       150 ~~~~l~~l~~~~  161 (202)
T 5MFO_F          150 ALWALSNIASGG  161 (202)
T ss_dssp             HHHHHHHHTTSC
T ss_pred             HHHHHHHHhcCh
Confidence            999999998765


No 288
>5MFO_E YIIIM3AIII; Designed armadillo repeat protein, peptide; HET: EDO, CA; 1.3A {synthetic construct}
Probab=91.58  E-value=0.007  Score=51.19  Aligned_cols=157  Identities=18%  Similarity=0.285  Sum_probs=120.0  Template_Neff=13.100

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .+.++.++..+. +.++.++..++..|.+++...+.     ....+.+.++++.|..++.+.++.++..++++|.+++..
T Consensus         3 ~~~~~~l~~~l~-~~~~~~~~~a~~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~~~a~~~l~~l~~~   76 (202)
T 5MFO_E            3 GSELPQMVQQLN-SPDQQELQSALRKLSQIASGGNE-----QIQAVIDAGALPALVQLLSSPNEQILQEALWALSNIASG   76 (202)
T ss_dssp             --CHHHHHHHTT-CSSHHHHHHHHHHHHHHHTSCHH-----HHHHHHHTTHHHHHHHHTTCSCHHHHHHHHHHHHHHTTS
T ss_pred             CchHHHHHHHhc-CCCHHHHHHHHHHHHHHHcCChH-----HHHHHHHCChHHHHHHHhhCCCHHHHHHHHHHHHHHhcC
Confidence            456788888887 47778888999999999875332     233445678899999999988889999999999999976


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                       +.. ..+...++++.+...+.+      .++.++..++.+|.+++...+.....+.+.++++.+..++.+. +..++..
T Consensus        77 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~  149 (202)
T 5MFO_E           77 GNEQIQAVIDAGALPALVQLLSS------PNEQILQEALWALSNIASGGNEQIQAVIDAGALPALVQLLSSP-NEQILQE  149 (202)
T ss_dssp             CHHHHHHHHHTTHHHHHHHHTTC------SCHHHHHHHHHHHHHHTTSCHHHHHHHHHTTHHHHHHHHTTCS-CHHHHHH
T ss_pred             CHHHHHHHHHCChHHHHHHHhcC------CCHHHHHHHHHHHHHHHcCCHHHHHHHHHCCHHHHHHHHhcCC-CHHHHHH
Confidence             333 333455678888888866      3678888999999999876455555555667888888888876 7888999


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      ++.+|.+++...
T Consensus       150 ~~~~l~~l~~~~  161 (202)
T 5MFO_E          150 ALWALSNIASGG  161 (202)
T ss_dssp             HHHHHHHHHTSC
T ss_pred             HHHHHHHHhcCH
Confidence            999999998765


No 289
>2QNA_A Importin subunit beta-1, Snurportin-1; Nuclear transport, import of spliceosomal; HET: SO4; 2.84A {Homo sapiens}
Probab=91.50  E-value=0.0073  Score=62.82  Aligned_cols=159  Identities=8%  Similarity=0.020  Sum_probs=86.8  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG--NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~--d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+....++.++..++.++..++.....     ....+ -..+++.+...+.+.  ++.++..++.++..++..
T Consensus       525 ~~~~l~~~l~~~~~~~v~~~a~~~l~~l~~~~~~-----~~~~~-~~~i~~~l~~~l~~~~~~~~v~~~~~~~l~~l~~~  598 (762)
T 2QNA_A          525 FKPFLGIGLKNYAEYQVCLAAVGLVGDLCRALQS-----NIIPF-CDEVMQLLLENLGNENVHRSVKPQILSVFGDIALA  598 (762)
T ss_pred             HHHHHHHHhCCCCCHHHHHHHHHHHHHHHHHhHH-----cchHh-HHhHHHHHHHHHcCCCCCHHHHHHHHHHHHHHHHH
Confidence            4555665565224567788888888888754221     01111 135667777777765  567888899999888765


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGN-----TSNSEDILSSACYTVRNLMASQPQLAKQYFS-----SSMLNNIINLCR  693 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~-----~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve-----~giL~~Ll~LL~  693 (747)
                       ... ..++ ..+++.+...+......     ...+..++..++.++..++...+.....+..     ...++.++.++.
T Consensus       599 ~~~~~~~~~-~~i~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~  677 (762)
T 2QNA_A          599 IGGEFKKYL-EVVLNTLQQASQAQVDKSDYDMVDYLNELRESCLEAYTGIVQGLKGDQENVHPDVMLVQPRVEFILSFID  677 (762)
T ss_pred             hhcchHHHH-HHHHHHHHHHHcCCCCCCCcccCCCCHHHHHHHHHHHHHHHHhCCCCCcCccccHHHHHhHHHHHHHHHH
Confidence             211 1111 23445555554421000     0014566778888888887642221111100     011344444443


Q NP_000290.2     694 ------SSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       694 ------s~~d~eVr~aAL~aLsnL~~~  714 (747)
                            +. +..++..++.+|..++..
T Consensus       678 ~~~~~~~~-~~~~~~~a~~~l~~l~~~  703 (762)
T 2QNA_A          678 HIAGDEDH-TDGVVACAAGLIGDLCTA  703 (762)
T ss_pred             HHcCCCCC-CHHHHHHHHHHHHHHHHH
Confidence                  22 467788888888887754


No 290
>6G4J_B Probable serine/threonine-protein kinase YabT (E.C.2.7.11.1); Bacterial Hanks-type protein kinase, complex; 1.599A {Bacillus subtilis (strain 168)}
Probab=91.47  E-value=0.008  Score=50.62  Aligned_cols=132  Identities=14%  Similarity=0.147  Sum_probs=85.5  Template_Neff=11.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      ..+.+++++. +.++.++..++..+..+..                ...++.+..++.+.++.++..++.++..+...  
T Consensus        15 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--   75 (148)
T 6G4J_B           15 KVEMYIKNLQ-DDSAVVRDYAAAALGKIGD----------------ERAVEPLIKALKDEDEYVRQSAAWALGEIGDE--   75 (148)
T ss_pred             cHHHHHHHhc-CCCHHHHHHHHHHHHhhCC----------------HHHHHHHHHHhCCCCHHHHHHHHHHHHHhCCH--
Confidence            4566777777 4667777777777765532                12344556667677788888888888877542  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.++..+...           ..++.+..++.+. ++.++..++.+
T Consensus        76 -------~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~  130 (148)
T 6G4J_B           76 -------RAVEPLIKALKD------EDPSVRLTAAEALGQIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  130 (148)
T ss_pred             -------HHHHHHHHHhcC------CCHHHHHHHHHHHHhhCCH-----------HHHHHHHHHhcCC-CHHHHHHHHHH
Confidence                   234455555554      3567888888888876531           2344555566555 67888999999


Q NP_000290.2     708 LSDMWSSKELQGVLRQ  723 (747)
Q Consensus       708 LsnL~~~~~~~~~~~~  723 (747)
                      |..+........-+++
T Consensus       131 L~~~~~~~~~~~~~~~  146 (148)
T 6G4J_B          131 LETHKSLISGGGGSGG  146 (148)
T ss_pred             HHhhCCCChHhccccc
Confidence            9888766555444443


No 291
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=91.29  E-value=0.0081  Score=65.72  Aligned_cols=98  Identities=9%  Similarity=0.152  Sum_probs=58.6  Template_Neff=13.000

Q NP_000290.2     609 SDVVRSGASLLSNMSRHPL-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLN  686 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~~e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~  686 (747)
                      ..++..++.++..++.... . .... ..+++.+...+.+      .++.++..++.+|..++...+...... ...+++
T Consensus       821 ~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~------~~~~~r~~a~~~l~~l~~~~~~~~~~~-~~~~~~  892 (1078)
T 3W3W_A          821 EDLLDEINKSIAAVLKTTNGHYLKNL-ENIWPMINTFLLD------NEPILVIFALVVIGDLIQYGGEQTASM-KNAFIP  892 (1078)
T ss_dssp             HHHHHHHHHHHHHHHHHHTTTHHHHH-GGGHHHHHHHHC--------CHHHHHHHHHHHHHHHTC--CCCHHH-HHHHHH
T ss_pred             HHHHHHHHHHHHHHHHhcccchHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhcchhhHHH-HHhHHH
Confidence            3455666677776665411 1 1111 2345556666554      356788888899988876432221111 124567


Q NP_000290.2     687 NIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       687 ~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+.+. ++.++..++.+|..++...
T Consensus       893 ~l~~~l~~~-~~~vr~~a~~~l~~l~~~~  920 (1078)
T 3W3W_A          893 KVTECLISP-DARIRQAASYIIGVCAQYA  920 (1078)
T ss_dssp             HHHHHHTCS-CHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHhcCC-CHHHHHHHHHHHHHHHHHC
Confidence            777777766 7889999999998888653


No 292
>3ND2_A Importin subunit beta-1; importin, karyopherin, nuclear import, receptor; 2.4A {Saccharomyces cerevisiae}
Probab=91.23  E-value=0.0083  Score=63.25  Aligned_cols=152  Identities=13%  Similarity=0.136  Sum_probs=86.1  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      .++.+...+.. .+ ..++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. 
T Consensus       598 ~~~~l~~~l~~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  670 (861)
T 3ND2_A          598 LMGLFFRLLEK-KDSAFIEDDVFYAISALAASLGK-----GFEK-YLETFSPYLLKALNQVDSPVSITAVGFIADISNSL  670 (861)
T ss_dssp             HHHHHHHHHHS-TTHHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHHTCTTSTHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHhc-CCCchhHHHHHHHHHHHHHHhhh-----hHHH-HHHhHHHHHHHHHcCCCchHHHHHHHHHHHHHHHc
Confidence            45555666652 33 55777888888887754221     0111 1235677777777777778888999999988865 


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP------  698 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~------  698 (747)
                      +.. .... ..+++.+...+...    ..+..++..++.++..++...+....... ..+++.+...+... ..      
T Consensus       671 ~~~~~~~~-~~~~~~l~~~l~~~----~~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~-~~~~~~~~  743 (861)
T 3ND2_A          671 EEDFRRYS-DAMMNVLAQMISNP----NARRELKPAVLSVFGDIASNIGADFIPYL-NDIMALCVAAQNTK-PENGTLEA  743 (861)
T ss_dssp             TTSSHHHH-HHHHHHHHHHHHCT----TCCTTHHHHHHHHHHHHHHHHGGGGGGGH-HHHHHHHHHHHTCC-CSSSSHHH
T ss_pred             chhhHHhH-HHHHHHHHHHHhCc----chhhhhHHHHHHHHHHHHHHcchhcHHHH-HHHHHHHHHHHccC-CCCCCHHH
Confidence            211 1111 23555555555541    01467788888999888765332111111 23455555555433 21      


Q NP_000290.2     699 -----KAAEAARLLLSDMWS  713 (747)
Q Consensus       699 -----eVr~aAL~aLsnL~~  713 (747)
                           .++..++.++..++.
T Consensus       744 ~~~~~~~~~~~l~~l~~~~~  763 (861)
T 3ND2_A          744 LDYQIKVLEAVLDAYVGIVA  763 (861)
T ss_dssp             HHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHH
Confidence                 455566666655443


No 293
>5OWU_A Importin subunit beta-1, Nucleoporin NUP1; nuclear transport, TRANSPORT PROTEIN; 2.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=91.23  E-value=0.0083  Score=63.25  Aligned_cols=152  Identities=13%  Similarity=0.136  Sum_probs=86.1  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      .++.+...+.. .+ ..++..++.++..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. 
T Consensus       598 ~~~~l~~~l~~-~~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  670 (861)
T 5OWU_A          598 LMGLFFRLLEK-KDSAFIEDDVFYAISALAASLGK-----GFEK-YLETFSPYLLKALNQVDSPVSITAVGFIADISNSL  670 (861)
T ss_dssp             HHHHHHHHHHS-TTGGGTHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHHHCTTSTHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHhc-CCCchhHHHHHHHHHHHHHHhhh-----hHHH-HHHhHHHHHHHHHcCCCchHHHHHHHHHHHHHHHc
Confidence            45555666652 33 55777888888887754221     0111 1235677777777777778888999999988865 


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASP------  698 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~------  698 (747)
                      +.. .... ..+++.+...+...    ..+..++..++.++..++...+....... ..+++.+...+... ..      
T Consensus       671 ~~~~~~~~-~~~~~~l~~~l~~~----~~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~-~~~~~~~~  743 (861)
T 5OWU_A          671 EEDFRRYS-DAMMNVLAQMISNP----NARRELKPAVLSVFGDIASNIGADFIPYL-NDIMALCVAAQNTK-PENGTLEA  743 (861)
T ss_dssp             GGGGHHHH-HHHHHHHHHHHTCT----TCCTTHHHHHHHHHHHHHHHHGGGGHHHH-HHHHHHHHHHHTCC-CSSSSHHH
T ss_pred             chhhHHhH-HHHHHHHHHHHhCc----chhhhhHHHHHHHHHHHHHHcchhcHHHH-HHHHHHHHHHHccC-CCCCCHHH
Confidence            211 1111 23555555555541    01467788888999888765332111111 23455555555433 21      


Q NP_000290.2     699 -----KAAEAARLLLSDMWS  713 (747)
Q Consensus       699 -----eVr~aAL~aLsnL~~  713 (747)
                           .++..++.++..++.
T Consensus       744 ~~~~~~~~~~~l~~l~~~~~  763 (861)
T 5OWU_A          744 LDYQIKVLEAVLDAYVGIVA  763 (861)
T ss_dssp             HHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHH
Confidence                 455566666655443


No 294
>5DFZ_B Vacuolar protein sorting-associated protein 38; Vps34, Vps15, Vps30, Vps38, Autophagy; 4.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=90.97  E-value=0.011  Score=70.63  Aligned_cols=159  Identities=14%  Similarity=0.083  Sum_probs=104.1  Template_Neff=9.900

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATL-EACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL---QSGNSDVVRSGASLLSN  621 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr-~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL---~s~d~eVr~~AL~aLsn  621 (747)
                      ..+++.|+.+|. +.++.++ ..|+.+|..+......   ......+...++++.|+.+|   .+.++.++..++.+|..
T Consensus       463 ~~~i~~L~~~l~-d~~~~vR~~~a~~~L~~l~~~~~~---~~~~~~~~~~~~lp~Li~~L~~~~d~~~~vr~~aa~~l~~  538 (1460)
T 5DFZ_B          463 DRVVPYFVCCFE-DSDQDVQALSLLTLIQVLTSVRKL---NQLNENIFVDYLLPRLKRLLISNRQNTNYLRIVFANCLSD  538 (1460)
T ss_pred             ccchHHHHHHhc-CCCHHHHHHHHHHHHHHhcCCCCc---cCCccccCcCChHHHHHHHHHhccCCCHHHHHHHHHHHHH
Confidence            457888999998 5788888 8999999988764221   00011223467899999999   88889999999999998


Q NP_000290.2     622 MSRHP--L-----------L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNN  687 (747)
Q Consensus       622 La~~~--e-----------~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~  687 (747)
                      +....  .           . ...+..++++.+..++...-  ...++.++..|+.+|..|+......   .....+++.
T Consensus       539 ~~~~~~~~~l~~l~~~~~~~~~~~l~~~~~~~l~~ll~~~l--~d~~~~VR~~A~~aL~~l~~~~~~~---~~~~~~l~~  613 (1460)
T 5DFZ_B          539 LAIIINRFQEFTFAQHCNDNSSTKYSAKLIQSVEDLTVSFL--TDNDTYVKMALLQNILPLCKFFGRE---RTNDIILSH  613 (1460)
T ss_pred             HHHHcCHHHHHHHHHhcccChhHHHHcChHHHHHHHHHHHh--cCCCHHHHHHHHHHHHHHhcccccc---ccHHhHHHH
Confidence            85430  0           0 01122234444444433200  0036789999999999987542111   111356778


Q NP_000290.2     688 IINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       688 Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      |+.++.+. ++.+|..|+.+|..+...
T Consensus       614 Li~ll~d~-~~~VR~~a~~aL~~i~~~  639 (1460)
T 5DFZ_B          614 LITYLNDK-DPALRVSLIQTISGISIL  639 (1460)
T ss_pred             HHHHhcCC-CHHHHHHHHHHHHHHHhh
Confidence            88888776 788888888888888763


No 295
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=90.68  E-value=0.011  Score=64.69  Aligned_cols=157  Identities=9%  Similarity=0.025  Sum_probs=84.5  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.++..+..+.+..++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.+|..++....
T Consensus       440 ~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~  514 (1078)
T 3W3U_A          440 ILPALISKLTSECTSRVQTHAAAALVAFSEFASK---D-ILEP-YLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAAK  514 (1078)
T ss_dssp             HHHHHHHHSSTTSCHHHHHHHHHHHHHHHTTCCH---H-HHGG-GHHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHcCCCCCHHHHHHHHHHHHHHHHhCCh---h-hhHH-HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhH
Confidence            4555666665224566777888888888764221   0 0111 123566677777777778888899999988876521


Q NP_000290.2     628 -LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR---SSASPKAAEA  703 (747)
Q Consensus       628 -~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~---s~~d~eVr~a  703 (747)
                       ........+++.+...+....   ..++.++..++.++..+................++.+..++.   +. +..++..
T Consensus       515 ~~~~~~~~~~~~~l~~~l~~~~---~~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~-~~~~~~~  590 (1078)
T 3W3U_A          515 NKFIKYYDTLMPLLLNVLKVNN---KDNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQNSDIDE-DDALRSY  590 (1078)
T ss_dssp             GGGGGGHHHHHHHHHHHHHCC-------HHHHHHHHHHHHHHHHHHCHHHHTTTHHHHHHHHHHHHTSSCCC-CHHHHHH
T ss_pred             HhHHHHHhhHHHHHHHHHhcCC---CCcchHHHHHHHHHHHHHHHHCHHHhHHHHHHHHHHHHHHhcCCCCC-CHHHHHH
Confidence             111111234555555554310   014567777888888776532111100011123444444444   23 4566777


Q NP_000290.2     704 ARLLLSDMWS  713 (747)
Q Consensus       704 AL~aLsnL~~  713 (747)
                      ++.++..++.
T Consensus       591 ~~~~l~~l~~  600 (1078)
T 3W3U_A          591 LEQSWSRICR  600 (1078)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            7777766654


No 296
>1QGR_A IMPORTIN BETA SUBUNIT, IMPORTIN ALPHA-2; TRANSPORT RECEPTOR, NUCLEAR IMPORT, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=90.57  E-value=0.011  Score=62.78  Aligned_cols=113  Identities=11%  Similarity=0.140  Sum_probs=66.6  Template_Neff=13.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL-E  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~-~  324 (747)
                      +++.+...+.+.++.++..++.++..++..............+++.+...+.+.+..++..++.++..++........ .
T Consensus       367 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~  446 (876)
T 1QGR_A          367 VLPFIKEHIKNPDWRYRDAAVMAFGCILEGPEPSQLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLPEAAIND  446 (876)
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCCHHhcHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhCChhhcCC
Confidence            344444555556677788888888887764322111111234556666666666778888899998888764432110 1


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. + ++.++..++.++..+...
T Consensus       447 ~~~~~~~~~l~~~l~-~-~~~v~~~a~~~l~~l~~~  480 (876)
T 1QGR_A          447 VYLAPLLQCLIEGLS-A-EPRVASNVCWAFSSLAEA  480 (876)
T ss_pred             chHHHHHHHHHHHhc-C-CHHHHHHHHHHHHHHHHH
Confidence            112245566666665 3 566777777777777653


No 297
>4QMH_A LP04448p; PROTEIN BINDING, TOG DOMAIN; 1.652A {Drosophila melanogaster}
Probab=90.39  E-value=0.012  Score=51.77  Aligned_cols=149  Identities=9%  Similarity=0.047  Sum_probs=95.9  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     .... .-..+++.+...+.+.+..++..++.+|..++....
T Consensus        58 ~~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  130 (241)
T 4QMH_A           58 LAPALAHRLV-DSNAKIAQTTLAICEQLATAMGA-----GCRN-HVRNLFPGFLHALGDNKSFVRAAALNCINSFGEKGG  130 (241)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHhcH-----HHHH-HHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHhcC
Confidence            4556666676 46778888999999988764221     1111 113566777777777777788888888888775421


Q NP_000290.2     628 LHRVMGNQVFPE--VTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-QYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       628 ~~~ll~~giI~~--Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .     ..+++.  +...+.+      .++.++..++.++..++...+.... ......+++.+...+.+. ++.++..+
T Consensus       131 ~-----~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a  198 (241)
T 4QMH_A          131 Y-----KEFFESEMIADALKG------GSPALKTELWAWLADKLPGLPPKSVSKEDIHSMVPHLYAHICDR-NADVRKNA  198 (241)
T ss_dssp             S-----GGGSSTTHHHHHHHT------CCHHHHHHHHHHHHHHGGGSCGGGSCHHHHHHHHHHHHHHTTCS-SHHHHHHH
T ss_pred             h-----HHhcCHHHHHHHHhC------CCHHHHHHHHHHHHHhccCCCcccCCHHHHHhHHHHHHHHHhCC-CHHHHHHH
Confidence            1     123333  5555554      3677888899999888764322110 011124567777777766 78899999


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.++..+....
T Consensus       199 ~~~l~~l~~~~  209 (241)
T 4QMH_A          199 NEAVLGIMIHL  209 (241)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHHHh
Confidence            99998887543


No 298
>5A1V_E ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=90.35  E-value=0.013  Score=64.93  Aligned_cols=102  Identities=12%  Similarity=0.008  Sum_probs=64.4  Template_Neff=10.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..++..+...+.+.+..++..+..++..+....+..      ..+++.+...+.+.+..++..++.++..+....     
T Consensus        67 ~~l~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~------~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~-----  135 (874)
T 5A1V_E           67 TEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV------IIVTSSLTKDMTGKEDNYRGPAVRALCQITDST-----  135 (874)
T ss_dssp             HHHHHHHHHGGGSCCHHHHHHHHHHHHHHHTSCSCG------GGHHHHHHHHHHSSSHHHHHHHHHHHHHHCCHH-----
T ss_pred             HHHHHHHHHHHcCCCHHHHHHHHHHHHHhcccCchH------hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHH-----
Confidence            345556666677777788888888887776532211      234555666666667778888888887664211     


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ....++..+...+. +.++.++..++.++..+..
T Consensus       136 --~~~~l~~~l~~~l~-d~~~~Vr~~a~~~l~~l~~  168 (874)
T 5A1V_E          136 --MLQAVERYMKQAIV-DKVPSVSSSALVSSLHLLK  168 (874)
T ss_dssp             --HHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHH
T ss_pred             --HHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHh
Confidence              01234455555665 5567788888888887765


No 299
>5NZR_G Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=90.35  E-value=0.013  Score=64.93  Aligned_cols=102  Identities=12%  Similarity=0.008  Sum_probs=64.4  Template_Neff=10.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..++..+...+.+.+..++..+..++..+....+..      ..+++.+...+.+.+..++..++.++..+....     
T Consensus        67 ~~l~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~------~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~-----  135 (874)
T 5NZR_G           67 TEAFFAMTKLFQSNDPTLRRMCYLTIKEMSCIAEDV------IIVTSSLTKDMTGKEDNYRGPAVRALCQITDST-----  135 (874)
T ss_pred             HHHHHHHHHHHcCCCHHHHHHHHHHHHHhcccCchH------hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHH-----
Confidence            345556666677777788888888887776532211      234555666666667778888888887664211     


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ....++..+...+. +.++.++..++.++..+..
T Consensus       136 --~~~~l~~~l~~~l~-d~~~~Vr~~a~~~l~~l~~  168 (874)
T 5NZR_G          136 --MLQAVERYMKQAIV-DKVPSVSSSALVSSLHLLK  168 (874)
T ss_pred             --HHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHh
Confidence              01234455555665 5567788888888887765


No 300
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=90.26  E-value=0.013  Score=64.05  Aligned_cols=157  Identities=10%  Similarity=0.054  Sum_probs=83.5  Template_Neff=13.000

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.++..+....++.++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.++..++...
T Consensus       439 ~~~~~l~~~l~~~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~-~~~~i~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  513 (1078)
T 3W3W_A          439 RILPALISKLTSECTSRVQTHAAAALVNFSEFASK---D-ILEP-YLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAA  513 (1078)
T ss_dssp             HHHHHHHHHTSTTSCHHHHHHHHHHHHHHHHTCCH---H-HHGG-GHHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHcccCCCHHHHHHHHHHHHHHHhcCCh---h-hHHH-HHHHHHHHHHHHHhcCCHHHHHHHHHHHHHHHHHh
Confidence            35566666665224567778888888887764221   0 0011 11355666777777667788888999998887652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCR---SSASPKA  700 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~---s~~d~eV  700 (747)
                      . . .... ..+++.+...+....   ..++.++..++.++..++.... ...... ...++..+...+.   +. +..+
T Consensus       514 ~~~~~~~~-~~~~~~l~~~l~~~~---~~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~-~~~v  587 (1078)
T 3W3W_A          514 KNKFIKYY-DTLMPLLLNVLKVNN---KDNSVLKGKCMECATLIGFAVGKEKFHEH-SQELISILVALQNSDIDE-DDAL  587 (1078)
T ss_dssp             GGGGGGGH-HHHHHHHHHHHHCC-------HHHHHHHHHHHHHHHHHHCHHHHTTT-HHHHHHHHHHHHTCC------HH
T ss_pred             HHhHHHHH-HhHHHHHHHHHHhCC---CCChHHHHHHHHHHHHHHHHHChhhhhHH-HHHHHHHHHHHhCCCCCC-chHH
Confidence            1 1 1111 234555555554310   0145677778888888765321 111111 1123444444444   23 4566


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       588 ~~~~~~~l~~l~~~  601 (1078)
T 3W3W_A          588 RSYLEQSWSRICRI  601 (1078)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            77777777666543


No 301
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=90.24  E-value=0.013  Score=64.03  Aligned_cols=158  Identities=9%  Similarity=0.045  Sum_probs=84.1  Template_Neff=13.000

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.++..+....++.++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.++..++...
T Consensus       439 ~~~~~l~~~l~~~~~~~~~~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~l~~~~  513 (1078)
T 5H2V_A          439 RILPALISKLTSECTSRVQTHAAAALVNFSEFASK---D-ILEP-YLDSLLTNLLVLLQSNKLYVQEQALTTIAFIAEAA  513 (1078)
T ss_dssp             HHHHHHHHTTSTTSCHHHHHHHHHHHHHHHTTCCH---H-HHGG-GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHcccCCCHHHHHHHHHHHHHHHhcCCh---h-hHHH-HHHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHHh
Confidence            35566666665224567778888888888764221   0 0011 12356666777777677788889999998887652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR---SSASPKAA  701 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~---s~~d~eVr  701 (747)
                      . . .... ..+++.+...+....   ..++.++..++.++..++..............+++.+...+.   +. +..++
T Consensus       514 ~~~~~~~~-~~~~~~l~~~l~~~~---~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~-~~~v~  588 (1078)
T 5H2V_A          514 KNKFIKYY-DTLMPLLLNVLKVNN---KDNSVLKGKCMECATLIGFAVGKEKFHEHSQELISILVALQNSDIDE-DDALR  588 (1078)
T ss_dssp             GGGGGGGH-HHHHHHHHHHHTCC-------HHHHHHHHHHHHHHHHHHCHHHHTTTHHHHHHHHHHHHTCC------CHH
T ss_pred             HHHHHHHH-HhHHHHHHHHHHhCC---CCChHHHHHHHHHHHHHHHHHCchhhhHHHHHHHHHHHHHhCCCCCC-chHHH
Confidence            1 1 1111 234555555554310   014567778888888876532111000011123444444444   23 45666


Q NP_000290.2     702 EAARLLLSDMWSS  714 (747)
Q Consensus       702 ~aAL~aLsnL~~~  714 (747)
                      ..++.++..++..
T Consensus       589 ~~~~~~l~~l~~~  601 (1078)
T 5H2V_A          589 SYLEQSWSRICRI  601 (1078)
T ss_dssp             HHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHH
Confidence            7777777666543


No 302
>4NEE_G AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=90.08  E-value=0.014  Score=56.75  Aligned_cols=141  Identities=15%  Similarity=0.147  Sum_probs=95.0  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. ++++.++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+++.+.....
T Consensus        77 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  145 (398)
T 4NEE_G           77 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  145 (398)
T ss_dssp             CHHHHHHHHT-CSSHHHHHHHHHHHHHSCCCCHH--------H--HHHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHHH
T ss_pred             hHHHHHHHHc-CCCccHHHHHHHHHHHHcCCCHH--------H--HHHHHHHHHHHHhCCCHHHHHHHHHHHHhcCCHHH
Confidence            4566777777 46778888888888888764221        1  12356667777777888899999999988764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+..++  .+      .++.++..++.+|..+....+..   +.....++.+...+.+. ++.++..++
T Consensus       146 -----~~~~~~~l~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  210 (398)
T 4NEE_G          146 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  210 (398)
T ss_dssp             -----HHHHTTHHHHHHHCSS------SCHHHHHHHHHHHHHHHHHCGGG---SCCSSHHHHHHGGGGCS-CHHHHHHHH
T ss_pred             -----HHHHHHhHHHHHhcCC------CCHHHHHHHHHHHHHHHHHChhh---ccccchHHHHHHHhcCC-CHHHHHHHH
Confidence                 112455566666  54      36788999999999987643221   11234567777777665 678888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       211 ~~l~~l~~~  219 (398)
T 4NEE_G          211 SLITTLAQK  219 (398)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHh
Confidence            888887764


No 303
>6MQ5_A CLIP-associating protein 1; Microtubule Plus End Binding, STRUCTURAL; HET: MSE; 2.146A {Homo sapiens}
Probab=89.98  E-value=0.015  Score=52.93  Aligned_cols=111  Identities=16%  Similarity=0.126  Sum_probs=61.3  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQL----IGLKEKGLPQIA-RLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~----llie~giI~~Ll-~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      .++.++..+. +.++.++..++..|..++.....     ...    ......+++.+. .++.+.++.++..++.++..+
T Consensus         4 ~l~~l~~~l~-~~~~~~r~~a~~~L~~~~~~~~~-----~~~~~~~~~~~~~~~~~l~~~~l~d~~~~vr~~a~~~l~~l   77 (257)
T 6MQ5_A            4 RMESCLAQVL-QKDVGKRLQVGQELIDYFSDKQK-----SADLEHDQTMLDKLVDGLATSWVNSSNYKVVLLGMDILSAL   77 (257)
T ss_dssp             SHHHHHHHHH-CCCHHHHHHHHHHHHHHHHCTTT-----TTTTTTCHHHHHHHHHHCCCCCTTCSSHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHh-cCCHHHHHHHHHHHHHHHhcccc-----ccccccCHHHHHHHHHHHHHHHhcCCcHHHHHHHHHHHHHH
Confidence            3555666676 46778888888888888764321     010    001234555555 456667778888899988888


Q NP_000290.2     623 SRHP-LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       623 a~~~-e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      +... .........+++.++..+.+      .+..++..++.+|..+..
T Consensus        78 ~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~  120 (257)
T 6MQ5_A           78 VTRLQDRFKAQIGTVLPSLIDRLGD------AKDSVREQDQTLLLKIMD  120 (257)
T ss_dssp             HHHHGGGGHHHHHHHHHHHHHHTTC------SCHHHHHHHHHHHHHHHH
T ss_pred             HHHhHHHHHHHHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            7651 11000111244444444443      234455555555555543


No 304
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=89.98  E-value=0.015  Score=60.62  Aligned_cols=109  Identities=11%  Similarity=0.011  Sum_probs=67.1  Template_Neff=12.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+..........+++.+...+.+.+..++..++.++..+.......   
T Consensus       160 ~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~L~~l~~~~~~~---  236 (657)
T 4UQI_B          160 GFLDSLRDLIADSNPMVVANAVAALSEISESHPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDRE---  236 (657)
T ss_pred             chHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCChhhhhhhhhcHHHHHHHHhcCCCHHHHHHHHHHHHhhCCCCHHH---
Confidence            34556666666777788888888888887653321111112345566666666666677777888887776432211   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ...+++.+...+. +.++.++..++.++..+..
T Consensus       237 --~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~  268 (657)
T 4UQI_B          237 --AQSICERVTPRLS-HANSAVVLSAVKVLMKFLE  268 (657)
T ss_pred             --HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHh
Confidence              1234555556665 4566778888888877765


No 305
>4XRI_A Importin Beta; Transport Protein, Nuclear Transport, Transport; HET: GOL, SO4; 2.05A {Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)}
Probab=89.95  E-value=0.014  Score=61.52  Aligned_cols=159  Identities=9%  Similarity=0.055  Sum_probs=88.2  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS--GNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s--~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.+...+....+..++..++.++..++.....     ....+ -..+++.+...+.+  .+..++..++.++..++..
T Consensus       651 ~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~~~  724 (882)
T 4XRI_A          651 FAPFLYNALGNQEEPSLCSMAIGLVSDVTRSLGE-----RSQPY-CDNFMNYLLGNLRSTTLANQFKPAILQCFGDIASA  724 (882)
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhhh-----ccHhh-HHHHHHHHHHHHcCCCCCHHHHHHHHHHHHHHHHh
Confidence            4566666665214566777888888877654221     01111 13466677777766  5677888999999988865


Q NP_000290.2     626 -PLL-HRVMGNQVFPEVTRLLTSHTGN------TSNSEDILSSACYTVRNLMASQPQL-----AKQYFSSSMLNNIINLC  692 (747)
Q Consensus       626 -~e~-~~ll~~giI~~Ll~LL~s~s~~------~~~d~eVr~~Al~aLsnLa~~s~e~-----~~~Lve~giL~~Ll~LL  692 (747)
                       +.. ..++ ..+++.+...+......      ......++..++.++..++......     ...+. ..+++.+...+
T Consensus       725 ~~~~~~~~~-~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~-~~i~~~l~~~~  802 (882)
T 4XRI_A          725 IGGHFETYL-TIVAQVLQQAATITAGPDGSYEMIDYVISLREGIMDAWGGIIGAMKTSNKTNVLQPYV-ESIFALLNSIA  802 (882)
T ss_pred             CCcccHhHH-HHHHHHHHHHhcCCCCCCCCccccccCHHHHHHHHHHHHHHHHhcChhcchhhchhcH-HhHHHHHHHHh
Confidence             211 1111 22444444444321000      0003456667777777776532211     11111 23456666666


Q NP_000290.2     693 RSSAS--PKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       693 ~s~~d--~eVr~aAL~aLsnL~~~~  715 (747)
                      .+. +  ..++..++.++..++...
T Consensus       803 ~~~-~~~~~vr~~a~~~l~~l~~~~  826 (882)
T 4XRI_A          803 NDP-NRSEALMRASMGVIGDLADAY  826 (882)
T ss_pred             cCC-CCCHHHHHHHHHHHHHHHHHh
Confidence            654 4  788889999998887543


No 306
>4NEE_B AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=89.83  E-value=0.016  Score=56.57  Aligned_cols=141  Identities=15%  Similarity=0.147  Sum_probs=94.8  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. +++..++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|+.+.....
T Consensus        77 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  145 (398)
T 4NEE_B           77 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  145 (398)
T ss_pred             hHHHHHHHhc-CCCHHHHHHHHHHHHHhcccCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHhhCCHHH
Confidence            4566777776 46778888888888888764221        1  12356667777777888899999999987764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+..++  .+      .++.++..++.+|..+....+..   +.....++.+...+.+. ++.++..++
T Consensus       146 -----~~~~~~~l~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  210 (398)
T 4NEE_B          146 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  210 (398)
T ss_pred             -----HHHHHHHHHHHHcCCC------CCHHHHHHHHHHHHHHHHHChhH---hcHhhHHHHHHHHhcCC-CHHHHHHHH
Confidence                 112455566666  54      36788999999999987643221   11234567777777665 778888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       211 ~~l~~l~~~  219 (398)
T 4NEE_B          211 SLITTLAQK  219 (398)
T ss_pred             HHHHHHHHh
Confidence            888887764


No 307
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=89.78  E-value=0.015  Score=61.60  Aligned_cols=153  Identities=8%  Similarity=0.015  Sum_probs=85.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .+..+...+. +....++..++.++..+......   ...... ....+++.+...+.+. ..++..++.+|..++....
T Consensus       397 ~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~---~~~~~~-~~~~~~~~l~~~l~~~-~~~~~~a~~~l~~l~~~~~  470 (852)
T 6EN4_C          397 IISRIVDDLK-DEAEQYRKMVMETIEKIMGNLGA---ADIDHK-LEEQLIDGILYAFQEQ-TTEDSVMLNGFGTVVNALG  470 (852)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCCh---hhcCHH-HHHHHHHHHHHhcCCC-HHHHHHHHHHHHHHHHcCC
Confidence            3445555555 34556677777777777653221   000011 1123445555555433 4677888888888876521


Q NP_000290.2     628 -L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 -~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                       . .... ..+++.+...+.+      .++.++..++.++..++..............+++.+...+.+. +..++..++
T Consensus       471 ~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v~~~a~  542 (852)
T 6EN4_C          471 KRVKPYL-PQICGTVLWRLNN------KSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEE-YPEVLGSIL  542 (852)
T ss_pred             hhhHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhChhhcCHHHHHhHHHHHHHHccCC-CHHHHHHHH
Confidence             1 1111 2345556666655      3678888999999988864322111112223566666666655 667788888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..++..
T Consensus       543 ~~l~~l~~~  551 (852)
T 6EN4_C          543 GALKAIVNV  551 (852)
T ss_pred             HHHHHHHHh
Confidence            888777654


No 308
>5A1V_E ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=89.57  E-value=0.018  Score=63.83  Aligned_cols=141  Identities=10%  Similarity=0.100  Sum_probs=80.8  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.|+.++.......++..++.++..++...+.          .....+..|...+.+ ..+.++..++++|+.+....
T Consensus       397 ~~~~L~~~L~~~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~l~~L~~~l~~~~~~~~~~~a~~~L~~~~~~~  466 (874)
T 5A1V_E          397 LMNFLFTMLREEGGFEYKRAIVDCIISIIEENSE----------SKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKT  466 (874)
T ss_dssp             HHHHHHHHHHHHSSSSHHHHHHHHHHHHTTTTHH----------HHHHHHHHHHTSCSSSSCHHHHHHHHHHHHHHCCSS
T ss_pred             HHHHHHHHHhhcCCchhHHHHHHHHHHHHHHCHH----------HHHHHHHHHHHHHHhcCCHHHHHHHHHHhcccccCC
Confidence            4555666665222233566677777776653221          112345556666553 34566777777777665431


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..++.+|..+....+.     ....++..|..++.+. +..++..|..
T Consensus       467 ~~----~~~~l~~l~~~l~~------~~~~vr~~al~aL~~l~~~~~~-----~~~~i~~~L~~~l~d~-~~~vR~~A~~  530 (874)
T 5A1V_E          467 NN----PSKYIRFIYNRVVL------EHEEVRAGAVSALAKFGAQNEE-----MLPSILVLLKRCVMDD-DNEVRDRATF  530 (874)
T ss_dssp             SC----HHHHHHHHHHHHHT------SCHHHHHHHHHHHHHHHHHCGG-----GHHHHHHHHHSTTTSS-SSHHHHHHHH
T ss_pred             CC----HHHHHHHHHHhhcc------CCHHHHHHHHHHHHHHHhcCHH-----HHHHHHHHHHHHccCC-CHHHHHHHHH
Confidence            11    01244555555554      3567888888888888764221     1123455555666555 7788888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      ++..+...
T Consensus       531 ~l~~l~~~  538 (874)
T 5A1V_E          531 YLNVLEQK  538 (874)
T ss_dssp             HHHHHHTS
T ss_pred             HHHHHHHh
Confidence            88876654


No 309
>5NZR_G Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=89.57  E-value=0.018  Score=63.83  Aligned_cols=141  Identities=10%  Similarity=0.100  Sum_probs=80.8  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.|+.++.......++..++.++..++...+.          .....+..|...+.+ ..+.++..++++|+.+....
T Consensus       397 ~~~~L~~~L~~~~~~~vr~~a~~~l~~l~~~~~~----------~~~~~l~~L~~~l~~~~~~~~~~~a~~~L~~~~~~~  466 (874)
T 5NZR_G          397 LMNFLFTMLREEGGFEYKRAIVDCIISIIEENSE----------SKETGLSHLCEFIEDCEFTVLATRILHLLGQEGPKT  466 (874)
T ss_pred             HHHHHHHHHhhcCCchhHHHHHHHHHHHHHHCHH----------HHHHHHHHHHHHHHhcCCHHHHHHHHHHhcccccCC
Confidence            4555666665222233566677777776653221          112345556666553 34566777777777665431


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..++.+|..+....+.     ....++..|..++.+. +..++..|..
T Consensus       467 ~~----~~~~l~~l~~~l~~------~~~~vr~~al~aL~~l~~~~~~-----~~~~i~~~L~~~l~d~-~~~vR~~A~~  530 (874)
T 5NZR_G          467 NN----PSKYIRFIYNRVVL------EHEEVRAGAVSALAKFGAQNEE-----MLPSILVLLKRCVMDD-DNEVRDRATF  530 (874)
T ss_pred             CC----HHHHHHHHHHhhcc------CCHHHHHHHHHHHHHHHhcCHH-----HHHHHHHHHHHHccCC-CHHHHHHHHH
Confidence            11    01244555555554      3567888888888888764221     1123455555666555 7788888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      ++..+...
T Consensus       531 ~l~~l~~~  538 (874)
T 5NZR_G          531 YLNVLEQK  538 (874)
T ss_pred             HHHHHHHh
Confidence            88876654


No 310
>6OWT_A AP-2 complex subunit alpha, AP-2; AP, HIV, Nef, trafficking, Protein;{Rattus norvegicus}
Probab=89.50  E-value=0.018  Score=64.23  Aligned_cols=98  Identities=19%  Similarity=0.075  Sum_probs=57.2  Template_Neff=11.000

Q NP_000290.2     250 AVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQN  329 (747)
Q Consensus       250 Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~~  329 (747)
                      ++.++.+.+...+..+...+..+.......     ...++..+...+.+.++.++..++.++..+....       ....
T Consensus        79 l~~ll~s~~~~~r~~~~~~l~~l~~~~~~~-----~~~ii~~l~~~l~~~~~~vr~~Al~~l~~~~~~~-------~~~~  146 (939)
T 6OWT_A           79 AVNLLSSNRYTEKQIGYLFISVLVNSNSEL-----IRLINNAIKNDLASRNPTFMGLALHCIANVGSRE-------MAEA  146 (939)
T ss_pred             HHHHhcCCCHHHHHHHHHHHHHHccCChHH-----HHHHHHHHHHHhcCCCHHHHHHHHHHHHHhcCHH-------HHHH
Confidence            334455555566666666666655432211     1134455556666667778888888887765321       1123


Q NP_000290.2     330 GIREAVSLL--RRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       330 IL~~Ll~lL--~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ++..+...+  . +.++.++..++.++..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vR~~a~~~L~~l~~~  178 (939)
T 6OWT_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRT  178 (939)
T ss_pred             HHHHHHHHHcCC-CCCHHHHHHHHHHHHHHHHH
Confidence            444555555  4 45677888888888887763


No 311
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=89.34  E-value=0.021  Score=68.25  Aligned_cols=151  Identities=13%  Similarity=0.081  Sum_probs=101.4  Template_Neff=9.500

Q NP_000290.2     548 AI-RTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I-~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++ +.|+.++. + .+..++..++..|..+....+.       .. ....+++.|...|.+.++.++..++.+|..++..
T Consensus       424 ~~~p~l~~ll~-~~~d~~~R~~al~~L~~~~~~~~~-------~~-~~~~i~p~l~~~l~d~~~~vr~~a~~~l~~l~~~  494 (1454)
T 5KC2_B          424 LFISYLSHSIR-SIVSTATKLKNLELLAVFAQFVSD-------EN-KIDRVVPYFVCCFEDSDQDVQALSLLTLIQVLTS  494 (1454)
T ss_pred             HhHHHHHHHhc-CCCCHHHHHHHHHHHHHHhhhCCH-------HH-HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            56 88999998 5 6777888888888887763221       11 2235688888888888999999999999999821


Q NP_000290.2     626 ----PLL-HRVMGNQVFPEVTRLL---TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY------------------  679 (747)
Q Consensus       626 ----~e~-~~ll~~giI~~Ll~LL---~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~L------------------  679 (747)
                          +.. ...+..++++.|..++   .+      .+..++..|+.+|..|+.........+                  
T Consensus       495 ~~~~~~~~~~~~~~~~l~~L~~ll~~~~d------~~~~vR~~a~~~l~~la~~~~~~~~~~~~~~~~~~~~~~~~~i~~  568 (1454)
T 5KC2_B          495 VRKLNQLNENIFVDYLLPRLKRLLISNRQ------NTNYLRIVFANCLSDLAIIINRFQEFTFAQHCNDNSMDNNTEIME  568 (1454)
T ss_pred             hhcCHHHHHHHHHcCcHHHHHHHHcCCCC------CcHHHHHHHHHHHHHHhcCCCCcceEEhhHHhhhHHHHHHHHHHH
Confidence                111 2234456778888888   65      367888999999998875422111111                  


Q NP_000290.2     680 ----FSSSMLNNIINLCRS----SASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       680 ----ve~giL~~Ll~LL~s----~~d~eVr~aAL~aLsnL~~~  714 (747)
                          ...++++.|..++..    . ++.++..|+.+|..+...
T Consensus       569 ~~~~~~~~~~~~l~~ll~~~l~d~-~~~vr~~a~~~l~~l~~~  610 (1454)
T 5KC2_B          569 SSTKYSAKLIQSVEDLTVSFLTDN-DTYVKMALLQNILPLCKF  610 (1454)
T ss_pred             HHHHHHcCHHHHHHHHHHhhcCCC-CHHHHHHHHHHHHHHhcC
Confidence                123345556555554    4 677777787777777653


No 312
>2P8Q_A Importin beta-1 subunit, Snurportin-1; HEAT repeat, IBB-domain, Importin, Karyopherin; 2.35A {Homo sapiens} SCOP: a.118.1.1
Probab=89.29  E-value=0.018  Score=60.92  Aligned_cols=154  Identities=10%  Similarity=0.087  Sum_probs=87.1  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....   . .... ....+++.+...+.+.++.++..++.++..++....
T Consensus       367 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~-~~~~i~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  440 (876)
T 2P8Q_A          367 VLPFIKEHIK-NPDWRYRDAAVMAFGCILEGPEP---S-QLKP-LVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLP  440 (876)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHTSSSSCH---H-HHHH-HHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhCCCh---h-hcHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHCc
Confidence            3555666666 46677888888888888764221   0 0111 123456677777777778899999999999887521


Q NP_000290.2     628 LH---RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK----------QYFS---SSMLNNIINL  691 (747)
Q Consensus       628 ~~---~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~----------~Lve---~giL~~Ll~L  691 (747)
                      ..   ......+++.+...+.+       ++.++..++.++..++........          ..+.   ..++..+...
T Consensus       441 ~~~~~~~~~~~~~~~l~~~l~~-------~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~  513 (876)
T 2P8Q_A          441 EAAINDVYLAPLLQCLIEGLSA-------EPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLET  513 (876)
T ss_dssp             GGTSSTTTHHHHHHHHHHHTTS-------CHHHHHHHHHHHHHHHHHHHHHHTSSSSSSSCSCCTTGGGHHHHHHHHHHH
T ss_pred             HHhccchhHHHHHHHHHHHccC-------CHHHHHHHHHHHHHHHHHHHHHhccCCCCCCcchhhccHhHHHHHHHHHHH
Confidence            10   11112345555555543       356777888888887754221100          0000   1234444444


Q NP_000290.2     692 CRS--SASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       692 L~s--~~d~eVr~aAL~aLsnL~~~  714 (747)
                      +..  ..+..++..++.++..+...
T Consensus       514 l~~~~~~~~~~r~~~~~~l~~l~~~  538 (876)
T 2P8Q_A          514 TDRPDGHQNNLRSSAYESLMEIVKN  538 (876)
T ss_dssp             TTCTTTTGGGHHHHHHHHHHHHHHS
T ss_pred             hcCCCCCcchHHHHHHHHHHHHHHh
Confidence            431  11456777777777776643


No 313
>2QNA_A Importin subunit beta-1, Snurportin-1; Nuclear transport, import of spliceosomal; HET: SO4; 2.84A {Homo sapiens}
Probab=89.10  E-value=0.019  Score=59.41  Aligned_cols=115  Identities=18%  Similarity=0.151  Sum_probs=67.9  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQD--EKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRS--PNQNVQQAAAGALRNLVFRSTT  320 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd--~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s--~d~eVr~~AL~aLs~La~~~~~  320 (747)
                      .+++.+...+.+.+  ..++..++.++..++...+..........+++.+...+.+  .++.++..++.++..++.....
T Consensus         3 ~l~~~l~~~l~~~~~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~~~~~~   82 (762)
T 2QNA_A            3 ELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKA   82 (762)
T ss_pred             chHHHHHHHhcCCCCCHHHHHHHHHHHHHHHHhCCHhhcHHHHHhHHHHHHHHhcCCCCCHHHHHHHHHHHHHHHhcCCc
Confidence            34555666666555  6788888888888775432211111112345666666653  3577888888888888754332


Q NP_000290.2     321 NKL-ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       321 ~~~-~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ... ......+++.+...+. +.++.++..++.++..++..
T Consensus        83 ~~~~~~~~~~i~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  122 (762)
T 2QNA_A           83 NFDKESERHFIMQVVCEATQ-CPDTRVRVAALQNLVKIMSL  122 (762)
T ss_pred             cCCcchhHHhHHHHHHHHhC-CCCHHHHHHHHHHHHHHHHh
Confidence            111 0111234555555665 45677888888888887763


No 314
>1IBR_B RAN  IMPORTIN BETA SUBUNIT; SMALL GTPASE  NUCLEAR TRANSPORT; HET: GNP; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=89.10  E-value=0.019  Score=55.65  Aligned_cols=154  Identities=11%  Similarity=0.066  Sum_probs=94.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|...+. +.+  +.++..++.+|..+......   . .... ....+++.+...+.+.+  ..++..++.++..++
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (462)
T 1IBR_B          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (462)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCG---G-GTGG-GHHHHHHHHHHHHSTTCCCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHhh-CCCCchHHHHHHHHHHHHHhhcCCH---H-HHHH-HHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            5666777776 344  67788888888888764221   0 0001 12456777788887766  889999999999887


Q NP_000290.2     624 RHPLL-H--RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~e~-~--~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ..... .  ......+...+..++.+      .++.++..++.+|..+...............+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v  275 (462)
T 1IBR_B          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (462)
T ss_dssp             TTTHHHHTSHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHCGGGCTTTTTTTHHHHHHHHHHCS-SHHH
T ss_pred             HHHHHhCCCHHHHHHHHHHHhHHhcC------CCHHHHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHHhcC-CHHH
Confidence            65211 0  11222233334444433      3567888889999888764333222222222366667777665 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       276 ~~~a~~~l~~l~~~  289 (462)
T 1IBR_B          276 ALQGIEFWSNVCDE  289 (462)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88898888888764


No 315
>1QGR_A IMPORTIN BETA SUBUNIT, IMPORTIN ALPHA-2; TRANSPORT RECEPTOR, NUCLEAR IMPORT, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=88.89  E-value=0.021  Score=60.61  Aligned_cols=154  Identities=10%  Similarity=0.084  Sum_probs=87.2  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....   . .... .-..+++.+...+.+.++.++..++.++..++....
T Consensus       367 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  440 (876)
T 1QGR_A          367 VLPFIKEHIK-NPDWRYRDAAVMAFGCILEGPEP---S-QLKP-LVIQAMPTLIELMKDPSVVVRDTAAWTVGRICELLP  440 (876)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHcCCH---H-hcHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhCC
Confidence            3455556666 36677888888888888764221   0 0111 123456677777777788899999999999887521


Q NP_000290.2     628 L--H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK----------QYFS---SSMLNNIINL  691 (747)
Q Consensus       628 ~--~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~----------~Lve---~giL~~Ll~L  691 (747)
                      .  . ......+++.+...+.+       ++.++..++.++..++........          ..+.   ..++..+...
T Consensus       441 ~~~~~~~~~~~~~~~l~~~l~~-------~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~  513 (876)
T 1QGR_A          441 EAAINDVYLAPLLQCLIEGLSA-------EPRVASNVCWAFSSLAEAAYEAADVADDQEEPATYCLSSSFELIVQKLLET  513 (876)
T ss_pred             hhhcCCchHHHHHHHHHHHhcC-------CHHHHHHHHHHHHHHHHHhhhccCCCCCCCCCcchhhhhhHHHHHHHHHHH
Confidence            1  0 11112345555555543       356777888888887754221100          0000   1234444444


Q NP_000290.2     692 CRS--SASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       692 L~s--~~d~eVr~aAL~aLsnL~~~  714 (747)
                      +..  ..+..++..++.++..++..
T Consensus       514 l~~~~~~~~~~r~~~~~~l~~l~~~  538 (876)
T 1QGR_A          514 TDRPDGHQNNLRSSAYESLMEIVKN  538 (876)
T ss_pred             hcCCCCCCHHHHHHHHHHHHHHHHc
Confidence            431  11456777788877777643


No 316
>2DB0_A 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=88.88  E-value=0.021  Score=50.55  Aligned_cols=141  Identities=13%  Similarity=0.132  Sum_probs=92.6  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+......        .  ....++.+...+.+.+..++..++.++..+.....
T Consensus       108 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~  176 (253)
T 2DB0_A          108 MIPVLFANYR-IGDEKTKINVSYALEEIAKANPM--------L--MASIVRDFMSMLSSKNREDKLTALNFIEAMGENSF  176 (253)
T ss_dssp             HHHHHHHHSC-CCSHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHTSCSSHHHHHHHHHHHHTCCTTTH
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhhcH
Confidence            4566677776 46778888888888887653211        1  13456667777777778888888888887654311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .   .....++.+...+.+      .++.++..++.+|..+....+      .....++.+...+.+. ++.++..++.+
T Consensus       177 ~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~------~~~~~~~~l~~~l~~~-~~~vr~~a~~~  240 (253)
T 2DB0_A          177 K---YVNPFLPRIINLLHD------GDEIVRASAVEALVHLATLND------KLRKVVIKRLEELNDT-SSLVNKTVKEG  240 (253)
T ss_dssp             H---HHGGGHHHHHGGGGC------SSHHHHHHHHHHHHHHHTSCH------HHHHHHHHHHHHCCCS-CHHHHHHHHHH
T ss_pred             H---hHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCH------HHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            0   011345556666665      367888899999998875322      1123466666667665 67889999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       241 l~~l~~~~  248 (253)
T 2DB0_A          241 ISRLLLLE  248 (253)
T ss_dssp             HHHHHHC-
T ss_pred             HHHHHHHh
Confidence            98887644


No 317
>2DB0_B 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=88.88  E-value=0.021  Score=50.55  Aligned_cols=141  Identities=13%  Similarity=0.132  Sum_probs=93.1  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+......        .  ....++.+...+.+.+..++..++.++..+.....
T Consensus       108 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~  176 (253)
T 2DB0_B          108 MIPVLFANYR-IGDEKTKINVSYALEEIAKANPM--------L--MASIVRDFMSMLSSKNREDKLTALNFIEAMGENSF  176 (253)
T ss_dssp             HHHHHTTTCC-CCSHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHGGGGCSSHHHHHHHHHHHTTCCTTTH
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhhcH
Confidence            4566677776 46778888888888887653211        1  13456667777777778888888888887654311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .   .....++.+...+.+      .++.++..++.+|..+....+      .....++.+...+.+. ++.++..++.+
T Consensus       177 ~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~------~~~~~~~~l~~~l~~~-~~~vr~~a~~~  240 (253)
T 2DB0_B          177 K---YVNPFLPRIINLLHD------GDEIVRASAVEALVHLATLND------KLRKVVIKRLEELNDT-SSLVNKTVKEG  240 (253)
T ss_dssp             H---HHGGGHHHHHGGGGC------SCHHHHHHHHHHHHHHHHHCH------HHHHHHHHHHHTCCCS-CHHHHHHHHHH
T ss_pred             H---hHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCH------HHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            0   011345556666665      367888899999998875322      1123466666667665 67889999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       241 l~~l~~~~  248 (253)
T 2DB0_B          241 ISRLLLLE  248 (253)
T ss_dssp             HHHHHTTC
T ss_pred             HHHHHHHh
Confidence            98887644


No 318
>4K92_B CLIP-associating protein 1; HEAT-Repeat TOG domain, Regulator of; HET: MSE; 2.005A {Homo sapiens}
Probab=88.82  E-value=0.022  Score=52.46  Aligned_cols=148  Identities=16%  Similarity=0.091  Sum_probs=93.3  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.+...+. +.+..++..++.+|..++.....     .... .-..+++.|+..+.+.+..++..++.+|..++....
T Consensus        90 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  162 (273)
T 4K92_B           90 LDGAFKLSAK-DLRSQVVREACITLGHLSSVLGN-----KFDH-GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH  162 (273)
T ss_dssp             THHHHHHHHT-CSCHHHHHHHHHHHHHHHHHHGG-----GGHH-HHHHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHH-cHHHHHHHHHHHHHHHHHHHHHH-----HhHH-HHHHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC
Confidence            4556666666 46778888899988888764221     0111 123466677777777777788888888888775421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.+|..++...........-..+++.+...+.+. +..++..++.+
T Consensus       163 ~-----~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~d~-~~~vr~~a~~~  230 (273)
T 4K92_B          163 I-----PRLIPVITSNCTS------KSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDA-DSEARIEARKC  230 (273)
T ss_dssp             C-----TTHHHHHHGGGGC------SCHHHHHHHHHHHHHHHHHSCHHHHTTCHHHHHHHHHHHHTCS-SHHHHHHHHHH
T ss_pred             C-----chHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcCchhHHHHHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            1     1234455555554      3577888888888888764322100011123566666777666 78899999999


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       231 l~~l~~~  237 (273)
T 4K92_B          231 YWGFHSH  237 (273)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8887754


No 319
>6MQ7_B CLIP-associating protein 1; microtubule binding protein, STRUCTURAL PROTEIN; 1.78A {Homo sapiens}
Probab=88.82  E-value=0.022  Score=52.46  Aligned_cols=148  Identities=16%  Similarity=0.091  Sum_probs=93.3  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.+...+. +.+..++..++.+|..++.....     .... .-..+++.|+..+.+.+..++..++.+|..++....
T Consensus        90 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~-~~~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  162 (273)
T 6MQ7_B           90 LDGAFKLSAK-DLRSQVVREACITLGHLSSVLGN-----KFDH-GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH  162 (273)
T ss_dssp             THHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHGG-----GGHH-HHHHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHH-cHHHHHHHHHHHHHHHHHHHHHH-----HhHH-HHHHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC
Confidence            4556666666 46778888899988888764221     0111 123466677777777777788888888888775421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.+|..++...........-..+++.+...+.+. +..++..++.+
T Consensus       163 ~-----~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~d~-~~~vr~~a~~~  230 (273)
T 6MQ7_B          163 I-----PRLIPVITSNCTS------KSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDA-DSEARIEARKC  230 (273)
T ss_dssp             C-----GGGHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHSCGGGTTTCHHHHHHHHHHHHTCS-SHHHHHHHHHH
T ss_pred             C-----chHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcCchhHHHHHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            1     1234455555554      3577888888888888764322100011123566666777666 78899999999


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       231 l~~l~~~  237 (273)
T 6MQ7_B          231 YWGFHSH  237 (273)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8887754


No 320
>1GCJ_B IMPORTIN-BETA; HEAT REPEAT MOTIF, NUCLEAR PORE-TARGETING; HET: MSE; 2.6A {Mus musculus} SCOP: a.118.1.1
Probab=88.73  E-value=0.022  Score=55.37  Aligned_cols=154  Identities=12%  Similarity=0.095  Sum_probs=94.5  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|+..+. +.+  +.++..++.+|..+......     .........+++.+...+.+.+  +.++..++.++..+.
T Consensus       135 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~-----~~~~~~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~~~  208 (460)
T 1GCJ_B          135 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP-----EQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  208 (460)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCH-----HHHGGGHHHHHHHHHHHHCTTCSCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHhh-CCCCcHHHHHHHHHHHHHHhhhCCH-----HHhHHHHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            4566777776 344  67788888888888764221     0000112356777777787665  889999999999887


Q NP_000290.2     624 RHPLL--H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~e~--~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .....  . ......+...+..++.+      .+..++..++.+|..+....+......+...+++.+..++.+. ++.+
T Consensus       209 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v  281 (460)
T 1GCJ_B          209 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  281 (460)
T ss_dssp             TTCHHHHTSHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHTTCGGGGGGTCCCCCHHHHHHHHTCS-SHHH
T ss_pred             HHHHHhCCCHHHHHHHHHHHHHHhCC------CCHHHHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhhCC-CHHH
Confidence            65111  1 11112233344444443      3567888889999888765333222222222366677777665 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       282 ~~~a~~~l~~l~~~  295 (460)
T 1GCJ_B          282 ALQGIEFWSNVCDE  295 (460)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88899988888764


No 321
>1F59_B IMPORTIN BETA-1/FXFG NUCLEOPORIN; Protein-protein complex, TRANSPORT PROTEIN RECEPTOR; 2.8A {Homo sapiens} SCOP: a.118.1.1
Probab=88.68  E-value=0.022  Score=54.84  Aligned_cols=154  Identities=11%  Similarity=0.067  Sum_probs=94.0  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.+...+. +.+  +.++..++.+|..+......   . .... ....+++.+..++.+.+  ..++..++.++..++
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (442)
T 1F59_B          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (442)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCG---G-GGGG-GHHHHHHHHHHTTSTTCCCHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHhh-CCCCcHHHHHHHHHHHHHHHhhCCH---H-HhHH-HHHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHH
Confidence            5666777776 344  67788888888887754221   0 0001 12456777777777766  889999999999987


Q NP_000290.2     624 RHPLL--H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~e~--~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .....  . ......+...+..++.+      .+..++..++.+|..++...+..........+++.+..++.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~v  275 (442)
T 1F59_B          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (442)
T ss_dssp             TTCHHHHHSHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHTGGGGGGTCCCCCHHHHHHHHHSS-CHHH
T ss_pred             HHHHHcCCCHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhcCC-cHHH
Confidence            65211  1 01112233333333333      3567888889999888765333322222222356666777655 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       276 ~~~a~~~l~~l~~~  289 (442)
T 1F59_B          276 ALQGIEFWSNVCDE  289 (442)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHhhH
Confidence            88899988888764


No 322
>1UKL_A Importin beta-1 subunit/Sterol regulatory element; Transcription factor, Nuclear transport factor; HET: MSE; 3.0A {Mus musculus} SCOP: a.118.1.1
Probab=88.63  E-value=0.022  Score=60.17  Aligned_cols=113  Identities=10%  Similarity=0.112  Sum_probs=64.3  Template_Neff=13.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTN-KLE  324 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~-~~~  324 (747)
                      +++.+...+.+.++.++..++.++..+...............+++.+...+.+.+..++..++.++..++...... ...
T Consensus       367 ~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~  446 (876)
T 1UKL_A          367 VLPFIKEHIKNPDWRYRDAAVMAFGSILEGPEPNQLKPLVIQAMPTLIELMKDPSVVVRDTTAWTVGRICELLPEAAIND  446 (876)
T ss_dssp             HHHHHHHHSSCSSHHHHHHHHHHHHTTSSSSCHHHHHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHCHHHHSCT
T ss_pred             HHHHHHHHccCCCHHHHHHHHHHHHHHHhCCChhhhHHHHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHHChHHhcCc
Confidence            3344444455566778888888888876543211111112345566666666667788888888888887543321 001


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. . ++.++..++.++..++..
T Consensus       447 ~~~~~~~~~l~~~l~-~-~~~~~~~~~~~l~~l~~~  480 (876)
T 1UKL_A          447 VYLAPLLQCLIEGLS-A-EPRVASNVCWAFSSLAEA  480 (876)
T ss_dssp             TTHHHHHHHHHHHTT-S-CHHHHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHhc-C-ChhHHHHHHHHHHHHHHH
Confidence            111234555555554 3 456677777777776653


No 323
>1U6G_C Cullin homolog 1, RING-box protein; cullin repeat, heat repeat, ring; 3.1A {Homo sapiens} SCOP: a.118.1.2
Probab=88.22  E-value=0.025  Score=62.86  Aligned_cols=146  Identities=12%  Similarity=0.093  Sum_probs=89.7  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. . ++.++..++.++..+....+.   . .... .-..+++.+...+.+.++.++..++.+|+.+.....
T Consensus       891 ~~~~l~~~l~-~-~~~~r~~~~~~l~~i~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  963 (1230)
T 1U6G_C          891 YLPFVLQEIT-S-QPKRQYLLLHSLKEIISSASV---V-GLKP-YVENIWALLLKHCECAEEGTRNVVAECLGKLTLIDP  963 (1230)
T ss_dssp             HHHHHHHHHH-S-CGGGHHHHHHHHHHHHHSSCS---T-TTHH-HHHHHHHHHTTCCCCSSTTHHHHHHHHHHHHHHSSG
T ss_pred             HHHHHHHHHc-c-CchHHHHHHHHHHHHHhcccc---c-ccHH-hHHHHHHHHHHHcCCCChhHHHHHHHHHHHHHccCH
Confidence            4555555554 2 455666777777777653221   0 0001 113466677777777788899999999988876421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                            ...++.+...+.+      .+..++..++.+|..+....+........ ..++.++..+.+. ++.++..++.+
T Consensus       964 ------~~~~~~l~~~l~~------~~~~~r~~~~~~l~~~~~~~~~~~~~~~~-~~~~~l~~~l~d~-~~~vr~~a~~~ 1029 (1230)
T 1U6G_C          964 ------ETLLPRLKGYLIS------GSSYARSSVVTAVKFTISDHPQPIDPLLK-NCIGDFLKTLEDP-DLNVRRVALVT 1029 (1230)
T ss_dssp             ------GGTHHHHTTTSSS------SCHHHHHHHHHHTGGGCCSSCCTHHHHHH-HHSTTTHHHHSSS-STHHHHHHHHH
T ss_pred             ------HhHHHHHHHHhhC------CCHHHHHHHHHHHHHHHcCCCCCccHHHH-HHHHHHHHHcCCC-CHHHHHHHHHH
Confidence                  1234555666654      25667788888888877643221111222 4567777777766 77888888888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus      1030 l~~l~~~ 1036 (1230)
T 1U6G_C         1030 FNSAAHN 1036 (1230)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHhc
Confidence            8888754


No 324
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=88.09  E-value=0.031  Score=59.08  Aligned_cols=135  Identities=14%  Similarity=0.062  Sum_probs=91.1  Template_Neff=8.700

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE---------SAKQQVYQLGGICKLVDLLRS------PNQNVQQAAAGA  310 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~---------~~~~~li~~~IL~~Ll~lL~s------~d~eVr~~AL~a  310 (747)
                      +++.|+.++.+.+..+...++.+|..++....         .....+...++++.++..+..      .+......++.+
T Consensus        69 ~i~~Lv~LL~~~n~~i~~~a~~~L~~Lt~~~~~~~~~~~~~~~~~~l~~~g~l~~Lv~~L~~~~e~~~~d~~~~~~al~~  148 (490)
T 4MFU_A           69 AVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAI  148 (490)
T ss_dssp             HHHHHHHHTSCSSHHHHHHHHHHHHHHHHGGGSSCCCHHHHHHHHHHHHTTHHHHHHHHHHHCCTTCHHHHHHHHHHHHH
T ss_pred             hHHHHHHHhCCCCHHHHHHHHHHHHHHcCcccccCChhhHHHHHHHHHhCCHHHHHHHHHHhccccccchHHHHHHHHHH
Confidence            45566677776667778888888888876432         122333445677777777764      456677888899


Q NP_000290.2     311 LRNLVFRSTTNKLETRRQNGIREAVSLLRRTG--NAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       311 Ls~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~--d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      |.+++...+.....+...++++.|+..+. ..  ...++..+..+|..++.. ......+.. ++++.|+.+|..
T Consensus       149 L~nL~~~~~~~~~~i~~~~~l~~Ll~~L~-~~~~~~~~k~~a~~~L~~L~~~~~~~~~~l~~~g~i~~Ll~lL~~  222 (490)
T 4MFU_A          149 VENMAEFRPEMCTEGAQQGLLQWLLKRLK-AKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSV  222 (490)
T ss_dssp             HHHHHHHSTTHHHHHCCCCCHHHHHHHHH-CCSCCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHHT
T ss_pred             HHHHhccCHHHHHHHHHCCHHHHHHHHHH-cCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHHHHHHHHHh
Confidence            99888654333333444567888888886 33  467788899999999875 333444444 788888888863


No 325
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=87.58  E-value=0.03  Score=55.48  Aligned_cols=141  Identities=14%  Similarity=0.110  Sum_probs=94.1  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.+..++..++.++..+....+.        .  ...+++.+...+.+.++.++..++.++..+.....
T Consensus        37 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  105 (570)
T 6CRI_I           37 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKI  105 (570)
T ss_dssp             GHHHHHHTCS-CSCHHHHHHHHHHHHHTTTTSTT--------G--GGTTHHHHHHHTSSSCHHHHHHHHHHHHHCCCTTT
T ss_pred             hHHHHHHhcc-CCCHHHHHHHHHHHHHHHccCHh--------H--HHHHHHHHHHHcCCCCHHHHHHHHHHHccCChhHH
Confidence            4555666676 46677888888888887754221        1  12345666777777788889999998888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+...   .....++.+...+.+. ++.++..++.+
T Consensus       106 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~~~~---~~~~~~~~l~~~l~~~-~~~vr~~a~~~  170 (570)
T 6CRI_I          106 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQLV---EDQGFLDTLKDLISDS-NPMVVANAVAA  170 (570)
T ss_dssp             -----TTTSHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHCHHHH---HHHTHHHHHHHHHTSS-SHHHHHHHHHH
T ss_pred             -----HHHHHHHHHHhcCC------CCHHHHHHHHHHHHHHHHhChhhh---hccchHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 12345556666665      367888999999998876433221   1134567777777766 77888889998


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      |..+...
T Consensus       171 l~~~~~~  177 (570)
T 6CRI_I          171 LSEIAES  177 (570)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHhh
Confidence            8888765


No 326
>3QML_D 78 kDa glucose-regulated protein homolog; Armadillo like repeats, CHAPERONE-PROTEIN TRANSPORT; HET: PO4; 2.31A {Saccharomyces cerevisiae}
Probab=87.49  E-value=0.038  Score=55.35  Aligned_cols=165  Identities=6%  Similarity=-0.069  Sum_probs=100.7  Template_Neff=7.900

Q NP_000290.2     534 ETNPKGSGWLYHSDAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEK--GLPQIA---RLLQ--  605 (747)
Q Consensus       534 ~~ni~~~~~lve~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~g--iI~~Ll---~LL~--  605 (747)
                      .+++.....+++.| ++.|+.++... ....++..|+++|+..+.+++.     ....+.+.+  +++.|+   ..|.  
T Consensus        56 ~hdid~a~~~~~~g-~~~L~~~l~~~~~~~~ir~~Aa~iigsa~qNNP~-----aq~~~~~~~~~~l~~Ll~~~~~L~~~  129 (315)
T 3QML_D           56 AHDYKHGYKIITHE-FALLANLSLNENLPLTLRELSTRVITSCLRNNPP-----VVEFINESFPNFKSKIMAALSNLNDS  129 (315)
T ss_dssp             HTSHHHHHHHHHHH-HHHHHHHHHCTTSCHHHHHHHHHHHHHHHTTCTT-----HHHHHHHHCTTHHHHHHHHHHHHHCC
T ss_pred             HccHHHHHHHHHch-HHHHHHHHhCCCCCHHHHHHHHHHHHHHHhhCHH-----HHHHHHHHCccHHHHHHHHHHhhccC
Confidence            34556666677888 88888888721 5678999999999999988764     344445555  677777   4443  


Q NP_000290.2     606 --SGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA------  676 (747)
Q Consensus       606 --s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~------  676 (747)
                        ..++.++..++.+|+.|+.+... ..+    ++..|..++...    ..+..++..++.++..+........      
T Consensus       130 ~~~~~~~v~~k~L~aLS~Lir~~~~~~~F----G~~~L~~~~~~~----~~~~~~~~K~l~ll~dl~~~~~~~~~~~~~~  201 (315)
T 3QML_D          130 NHRSSNILIKRYLSILNELPVTSEDLPIY----STVVLQNVYERN----NKDKQLQIKVLELISKILKADMYENDDTNLI  201 (315)
T ss_dssp             ---CTHHHHHHHHHHHHHSCCCGGGGGGS----CHHHHHHHHHTT----TTCHHHHHHHHHHHHHHHTTTC------CHH
T ss_pred             CCcCCHHHHHHHHHHHHhhcCCCccHhhh----cHHHHHHHHHhC----CCCHHHHHHHHHHHHHHHHhccccCCCcchH
Confidence              35677888999999999987322 222    456666666431    0135677788888888775432211      


Q NP_000290.2     677 --------KQYFSSSMLNNIINLCRSS-ASPKAAEAARLLLSDMW  712 (747)
Q Consensus       677 --------~~Lve~giL~~Ll~LL~s~-~d~eVr~aAL~aLsnL~  712 (747)
                              ......+.+..+...+... .+....+.++.+|..|.
T Consensus       202 ~~~~~~~~~~~~~~~~c~~l~~~L~~~~~d~~~~ek~l~~L~~L~  246 (315)
T 3QML_D          202 LFKRNAENWSSNLQEWANEFQEMVQNKSIDELHTRTFFDTLYNLK  246 (315)
T ss_dssp             HHHHHHHTTCSCCHHHHHHHHHHTTCTTSCHHHHHHHHHHHHHHH
T ss_pred             HhHhhccccchhHHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHH
Confidence                    1111133445555555421 13455566666666554


No 327
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=87.43  E-value=0.036  Score=65.15  Aligned_cols=154  Identities=8%  Similarity=0.029  Sum_probs=84.9  Template_Neff=9.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++..++..+. +.+..++..++.+|..++.....  .. .... ....+++.+...+... ...+..++.+|..++...
T Consensus       848 ~il~~l~~~l~-d~~~~~r~~a~~~L~~l~~~~~~--~~-~~~~-~~~~li~~ll~~l~~~-~~~r~~al~~L~~l~~~~  921 (1304)
T 5IFE_C          848 EIISRIVDDLK-DEAEQYRKMVMETIEKIMGNLGA--AD-IDHK-LEEQLIDGILYAFQEQ-TTEDSVMLNGFGTVVNAL  921 (1304)
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcCh--hh-hHHH-HHHHHHHHHHHHhcCC-HHHHHHHHHHHHHHHHhC
Confidence            34556666666 35556777788888777653211  00 0001 1123444455444432 356677788887777652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      . . ..++ ..++..+...+.+      .+..++..++.+|..++..............++..|...+.+. ++.++..+
T Consensus       922 ~~~~~~~l-~~l~~~L~~~L~~------~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~-~~~vr~~a  993 (1304)
T 5IFE_C          922 GKRVKPYL-PQICGTVLWRLNN------KSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEE-YPEVLGSI  993 (1304)
T ss_pred             HHHhHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCC-CHHHHHHH
Confidence            1 1 1111 2355556666655      3678888999999998764222111111123456666666654 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       994 l~aL~~l~~~ 1003 (1304)
T 5IFE_C          994 LGALKAIVNV 1003 (1304)
T ss_pred             HHHHHHHHHh
Confidence            7777776644


No 328
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=87.43  E-value=0.036  Score=65.15  Aligned_cols=154  Identities=8%  Similarity=0.029  Sum_probs=84.9  Template_Neff=9.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++..++..+. +.+..++..++.+|..++.....  .. .... ....+++.+...+... ...+..++.+|..++...
T Consensus       848 ~il~~l~~~l~-d~~~~~r~~a~~~L~~l~~~~~~--~~-~~~~-~~~~li~~ll~~l~~~-~~~r~~al~~L~~l~~~~  921 (1304)
T 6AHD_1          848 EIISRIVDDLK-DEAEQYRKMVMETIEKIMGNLGA--AD-IDHK-LEEQLIDGILYAFQEQ-TTEDSVMLNGFGTVVNAL  921 (1304)
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcCh--hh-hHHH-HHHHHHHHHHHHhcCC-HHHHHHHHHHHHHHHHhC
Confidence            34556666666 35556777788888777653211  00 0001 1123444455444432 356677788887777652


Q NP_000290.2     627 L-L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e-~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      . . ..++ ..++..+...+.+      .+..++..++.+|..++..............++..|...+.+. ++.++..+
T Consensus       922 ~~~~~~~l-~~l~~~L~~~L~~------~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~-~~~vr~~a  993 (1304)
T 6AHD_1          922 GKRVKPYL-PQICGTVLWRLNN------KSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEE-YPEVLGSI  993 (1304)
T ss_pred             HHHhHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCC-CHHHHHHH
Confidence            1 1 1111 2355556666655      3678888999999998764222111111123456666666654 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       994 l~aL~~l~~~ 1003 (1304)
T 6AHD_1          994 LGALKAIVNV 1003 (1304)
T ss_pred             HHHHHHHHHh
Confidence            7777776644


No 329
>5MU7_A Coatomer subunit beta, Coatomer subunit; coatomer, COPI, beta COP, delta; 2.57A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=87.43  E-value=0.031  Score=52.40  Aligned_cols=141  Identities=16%  Similarity=0.154  Sum_probs=92.9  Template_Neff=12.800

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      ++.++..+. +.++.++..++.+|..+....+.          .....++.+...+.+.+..++..++.+|..+......
T Consensus       190 ~~~l~~~l~-~~~~~~~~~a~~~l~~~~~~~~~----------~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~  258 (373)
T 5MU7_A          190 LGTVFEGIP-NAEELLQLVEIEFIRKDALHNPQ----------NKPRYLRLIFDLLEANTSTVVYEAASSLTALTNNPVA  258 (373)
T ss_dssp             HHHTGGGGG-GSCHHHHHHHHHHHHHHHHHCGG----------GHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHCCCHHH
T ss_pred             HHHHHhcCC-ChhHHHHHHHHHHHHHHhccCcc----------cHHHHHHHHHHHHhcCCHHHHHHHHHHHHHcCCCHHH
Confidence            455566666 35667777888888887653221          1234566777777777788888888888887743211


Q NP_000290.2     629 HRVMGNQVFPEVTRLLT-SHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~-s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                         . ..+++.+...+. +      .++.++..++.+|..+....+..    + ...++.+...+.+. ++.++..++.+
T Consensus       259 ---~-~~~~~~l~~~l~~~------~~~~vr~~a~~~l~~l~~~~~~~----~-~~~~~~l~~~l~~~-~~~vr~~a~~~  322 (373)
T 5MU7_A          259 ---V-KAAAGKFIELAIKE------ADNNVKLIVLDRVDQLRQKNEGI----L-DDLIMEILRVLSSP-DIDVRRKALEI  322 (373)
T ss_dssp             ---H-HHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHTTTT----T-GGGHHHHHHGGGSS-CHHHHHHHHHH
T ss_pred             ---H-HHHHHHHHHHHhhC------CChhHHHHHHHHHHHHHHhCHHH----H-HHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence               1 134556666665 4      36788889999999887643211    1 13566677777665 77889999999


Q NP_000290.2     708 LSDMWSSKE  716 (747)
Q Consensus       708 LsnL~~~~~  716 (747)
                      |..+.....
T Consensus       323 l~~~~~~~~  331 (373)
T 5MU7_A          323 ALEMVSSKN  331 (373)
T ss_dssp             HHTTCCTTT
T ss_pred             HHHHhcCCC
Confidence            998876544


No 330
>5VE8_B Kap123, Histone H3; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.7A {Kluyveromyces lactis}
Probab=87.41  E-value=0.031  Score=61.14  Aligned_cols=154  Identities=11%  Similarity=0.104  Sum_probs=81.3  Template_Neff=12.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      ++.+...+. ..++.++..++.++..++.....      ... ....+++.++..+ .+.++.++..++.++..++.. +
T Consensus       868 ~~~l~~~~~-~~~~~~r~~~~~~l~~l~~~~~~------~~~-~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~  939 (1116)
T 5VE8_B          868 KPVILQLCQ-SKSKNKRSFAVGALSEIALGMRD------ENP-FIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSS  939 (1116)
T ss_dssp             HHHHHHHTT-CSCHHHHHHHHHHHHHHHHHHGG------GCT-THHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHcC-CCCHHHHHHHHHHHHHHHHhCCC------Cch-hHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHhCC
Confidence            333444443 24556677777777777653221      111 1134555555553 345678889999999888865 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGN----------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSS  695 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~----------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~  695 (747)
                      .. ...+ ..+++.|...+......          ......++..++.+|+.+....+...   ....+++.++..+...
T Consensus       940 ~~~~~~~-~~il~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~---~~~~~l~~~~~~l~~~ 1015 (1116)
T 5VE8_B          940 FDVSAIY-SPVLKSLYEILSVADEKNLATEDDEATKEIVDRTFSNVCGCVARMILKHQNLV---PLEHTIPALLSHLPFN 1015 (1116)
T ss_dssp             SCCHHHH-HHHHHHHHHHHHHHHHHC-----CHHHHHHHHHHHHHHHHHHHHHHHHCGGGS---CHHHHHHHHHTTCSCS
T ss_pred             cchhhhH-HHHHHHHHHHhcchhHhccCCCCchhhHHHHHHHHHHHHHHHHHHHHHCcccC---CHHHHHHHHHhcCCCC
Confidence            11 1111 23555566555431000          00245667788888888876533211   1123455555555322


Q NP_000290.2     696 ASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       696 ~d~eVr~aAL~aLsnL~~~  714 (747)
                      .+...+..++.+|..+...
T Consensus      1016 ~~~~~~~~~~~~l~~l~~~ 1034 (1116)
T 5VE8_B         1016 TAFEEYDPIFKLFLKLFQE 1034 (1116)
T ss_dssp             SCGGGHHHHHHHHHHHHHT
T ss_pred             CchhhhHHHHHHHHHHHHh
Confidence            1455666677777766543


No 331
>2IX8_A ELONGATION FACTOR 3A; NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, PHOSPHORYLATION, ELONGATION; 6.0A {SACCHAROMYCES CEREVISIAE}
Probab=87.28  E-value=0.034  Score=61.28  Aligned_cols=150  Identities=9%  Similarity=0.007  Sum_probs=99.4  Template_Neff=11.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|...+. +.++.++..++.+|..+......     .... ....+++.|...+.+.++.++..|+.+|..++...
T Consensus        48 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  120 (976)
T 2IX8_A           48 HFFGELAKGIK-DKKTAANAMQAVAHIANQSNLSP-----SVEP-YIVQLVPAICTNAGNKDKEIQSVASETLISIVNAV  120 (976)
T ss_dssp             HHHHHHHHHHT-STTTHHHHHHHHHHHSCTTTCCT-----TTHH-HHHTTHHHHHHHTTCSSHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHcc-CHHHHHHHHHHHHHHHHHhccCc-----ccHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhc
Confidence            45677777777 46677888888888888753221     0111 12356777777888888889999999999887652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLL-TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL-~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ....  ...+++.|...+ .+      .++.++..++.+|..++...+....... ..+++.+..++.+. +..++..++
T Consensus       121 ~~~~--~~~~l~~l~~~l~~~------~~~~vr~~al~~L~~l~~~~~~~~~~~~-~~~~~~l~~~l~d~-~~~vr~~a~  190 (976)
T 2IX8_A          121 NPVA--IKALLPHLTNAIVET------NKWQEKIAILAAFSAMVDAAKDQVALRM-PELIPVLSETMWDT-KKEVKAAAT  190 (976)
T ss_dssp             CGGG--HHHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHSHHHHHHHH-HHHHHHHHHHTTCS-CHHHHHHHH
T ss_pred             CHHH--HHHHHHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHHHHhHHhhc-hhHHHHHHHhhcCC-CHHHHHHHH
Confidence            1111  123556666666 33      3567888899999988864322211111 24677777777766 788899999


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       191 ~~l~~l~~  198 (976)
T 2IX8_A          191 AAMTKATE  198 (976)
T ss_dssp             HHHHHHST
T ss_pred             HHHHHHHH
Confidence            99888876


No 332
>3WOY_A CLIP-associating protein 2; HEAT Repeat, Microtubule binding, Tubulin; 2.1A {Homo sapiens}
Probab=87.26  E-value=0.034  Score=50.12  Aligned_cols=147  Identities=14%  Similarity=0.116  Sum_probs=92.3  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.+..++..++.++..++.....     ....+ -..+++.+...+.+....++..+..++..++....
T Consensus        78 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~-----~~~~~-~~~l~~~l~~~l~~~~~~vr~~a~~~l~~i~~~~~  150 (251)
T 3WOY_A           78 LDGALKLSAK-DLRSQVVREACITVAHLSTVLGN-----KFDHG-AEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTH  150 (251)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHHCc-----ccHHH-HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCC
Confidence            4555666666 46678888899999888764321     01111 13456667777766677788888888888875421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-AKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .     ..+++.+...+.+      .++.++..++.++..++...... .... -..+++.+...+.+. +..++..++.
T Consensus       151 ~-----~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~-~~~i~~~l~~~l~d~-~~~vr~~a~~  217 (251)
T 3WOY_A          151 V-----PRLIPLITSNCTS------KSVPVRRRSFEFLDLLLQEWQTHSLERH-AAVLVETIKKGIHDA-DAEARVEARK  217 (251)
T ss_pred             H-----hhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHHCHHhhHHh-HHHHHHHHHHHhcCC-CHHHHHHHHH
Confidence            1     1244455555554      35677888888888887542211 1111 123566677777766 7889999999


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      ++..+...
T Consensus       218 ~l~~l~~~  225 (251)
T 3WOY_A          218 TYMGLRNH  225 (251)
T ss_pred             HHHHHHHH
Confidence            88887754


No 333
>5DN7_A Protein FAM179B; TOG domain, STRUCTURAL PROTEIN; 2.2A {Mus musculus}
Probab=87.22  E-value=0.035  Score=51.97  Aligned_cols=146  Identities=10%  Similarity=0.046  Sum_probs=94.2  Template_Neff=11.400

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....     .... .-..+++.|...+.+.+..++..++.+|..+.....
T Consensus        67 l~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-----~~~~-~~~~l~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  139 (293)
T 5DN7_A           67 FISLLYNLLD-DSNFKVVHGTLQVLHLLVIRLGE-----QVQQ-FLGPVIAASVKVLADNKLVIKQEYMKIFLKLMKEVG  139 (293)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHHHHHHGG-----GGGG-GHHHHHHHHHHGGGCCCHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHHHH-----HHHH-HHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHHC
Confidence            4555666666 46778888889888888764221     0111 113467777777777778888889998888875311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.++..+........  ..-..+++.+...+.+. +..++..++.+
T Consensus       140 ~-----~~~~~~l~~~l~~------~~~~vr~~al~~l~~l~~~~~~~~--~~~~~~~~~l~~~l~d~-~~~vr~~a~~~  205 (293)
T 5DN7_A          140 P-----QRVLSLLLENLKH------KHSRVREEVVNICICSLLTYPSED--FDLPKLSFDLAPALVDS-KRRVRQAALEA  205 (293)
T ss_dssp             H-----HHHHHHHHGGGGC------SCHHHHHHHHHHHHHHHHHSCGGG--SCHHHHHHHHGGGGGCS-SHHHHHHHHHH
T ss_pred             H-----HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhCCccc--CCHHHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence            1     1244555555554      367788888888888876432211  11124566677777766 78888889888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       206 l~~l~~~  212 (293)
T 5DN7_A          206 FAVLASS  212 (293)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8887653


No 334
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=87.21  E-value=0.04  Score=59.57  Aligned_cols=135  Identities=14%  Similarity=0.062  Sum_probs=91.1  Template_Neff=8.100

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDE---------SAKQQVYQLGGICKLVDLLRS------PNQNVQQAAAGA  310 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~---------~~~~~li~~~IL~~Ll~lL~s------~d~eVr~~AL~a  310 (747)
                      .++.|+.++.+.+..+...++.+|..+.....         .....+...++++.|+..+..      .+...+..++.+
T Consensus       147 ~i~~Lv~LL~~~n~di~~~a~~~L~~Lt~~~~~~~~~~~~~~l~~~l~e~g~l~~Lv~~L~~l~e~~~~d~~~~~~al~i  226 (568)
T 4HM9_A          147 AVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAI  226 (568)
T ss_dssp             HHHHHHHGGGCSSHHHHHHHHHHHHHHTCHHHHTTCHHHHHHHHHHHHHTTHHHHHHHHHTTCCTTSHHHHHHHHHHHHH
T ss_pred             hHHHHHHHhCCCCHHHHHHHHHHHHHHhCCccccCChhhHHHHHHHHHhCCHHHHHHHHHhcccccccchHHHHHHHHHH
Confidence            45566677776667788888888888875432         112333445677777777765      455677888999


Q NP_000290.2     311 LRNLVFRSTTNKLETRRQNGIREAVSLLRRTG--NAEIQKQLTGLLWNLSST-DELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       311 Ls~La~~~~~~~~~ll~~~IL~~Ll~lL~ss~--d~eVr~~AL~aLsnLas~-~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      |.+++...+.....+...+++..|+.++. ..  ....+..+..+|..|+.. ......+.. ++++.|+.+|..
T Consensus       227 L~nL~~~~~~~~~~i~~~g~l~~Ll~lL~-~~~~~~~~k~~AaeiL~~L~~~~~~~r~~l~~~g~I~~LL~lL~~  300 (568)
T 4HM9_A          227 VENMAEFRPEMCTEGAQQGLLQWLLKRLK-AKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSV  300 (568)
T ss_dssp             HHHHHHHCGGGHHHHCCCCCHHHHHHHHH-SSCCCCHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHHGG
T ss_pred             HHHHhccCHHHHHHHHHCCHHHHHHHHHH-cCCCCHHHHHHHHHHHHHHHcCCHHHHHHHHhCchHHHHHHHHHh
Confidence            99888653332223344567888888886 33  456788899999999875 344444444 888989988864


No 335
>6S47_Bi 60S ribosomal protein L2-A, 60S; New1, ABCF, Ribosomal Protein, Recycling; HET: ATP; 3.28A {Saccharomyces cerevisiae}
Probab=87.16  E-value=0.035  Score=61.24  Aligned_cols=155  Identities=12%  Similarity=0.055  Sum_probs=101.1  Template_Neff=11.700

Q NP_000290.2     546 SDAIRTYLNLMGKS-KKDATLEACAGALQNLTASK-GLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       546 ~G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s-~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .++++.|..++. + .++.++..++.+|..++... ..   . ....+. ..+++.|...+.+.++.++..++.+|..++
T Consensus        42 ~~il~~l~~~l~-~~~~~~vr~~a~~~L~~l~~~~~~~---~-~~~~~~-~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~  115 (972)
T 6S47_Bi          42 WKIVDVLSKFIK-PKNPSLVRESAMLIISNIAQFFSGK---P-PQEAYL-LPFFNVALDCISDKENTVKRAAQHAIDSLL  115 (972)
T ss_pred             ccHHHHHHHHcC-CCCCHHHHHHHHHHHHHHHhcCCCh---h-hcHHHH-HHHHHHHHHHhCCCCHHHHHHHHHHHHHHH
Confidence            346777777777 4 56778888999998887643 10   0 001111 236777778888778889999999999887


Q NP_000290.2     624 RHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       624 ~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      ..... ......+++.|..++.+.     .++.++..++.+|+.++..............+++.|+..+.+. ++.++..
T Consensus       116 ~~~~~-~~~~~~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~i~~~~~~~~~~~~~~~~~~~l~~~l~d~-~~~vr~~  188 (972)
T 6S47_Bi         116 NCFPM-EALTCFVLPTILDYLSSG-----AKWQAKMAALSVVDRIREDSANDLLELTFKDAVPVLTDVATDF-KPELAKQ  188 (972)
T ss_pred             hcCCH-HhhHhchHHHHHHHcCCC-----CCHHHHHHHHHHHHHHHhhCCHHHHHHHHHHHHHHHHHHhcCC-CHHHHHH
Confidence            65111 111113566677776652     1278889999999998554322211112234677777788766 7889999


Q NP_000290.2     704 ARLLLSDMWS  713 (747)
Q Consensus       704 AL~aLsnL~~  713 (747)
                      ++.+|..+..
T Consensus       189 a~~~L~~l~~  198 (972)
T 6S47_Bi         189 GYKTLLDYVS  198 (972)
T ss_pred             HHHHHHHHHH
Confidence            9999988775


No 336
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=87.12  E-value=0.034  Score=55.81  Aligned_cols=142  Identities=13%  Similarity=0.105  Sum_probs=94.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. ++++.++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        50 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  118 (592)
T 6QH5_B           50 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKI  118 (592)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCHH--------H--HHHHHHHHHHHccCCCHHHHHHHHHHHHHHcchhh
Confidence            4555666666 46677888888888887654221        1  13456667777778888899999999888765311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+..   ......++.+...+.+. ++.++..++.+
T Consensus       119 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~---~~~~~~~~~l~~~l~d~-~~~vr~~a~~~  183 (592)
T 6QH5_B          119 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQM---VEDQGFLDSLRDLIADS-NPMVVANAVAA  183 (592)
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCchh---hcCccHHHHHHHHhCCC-CHHHHHHHHHH
Confidence                 12345556666655      36788899999999887643221   12234567777777765 77888889888


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       184 l~~~~~~~  191 (592)
T 6QH5_B          184 LSEISESH  191 (592)
T ss_pred             HHHHHhcC
Confidence            88887654


No 337
>5A1V_G ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=87.07  E-value=0.037  Score=61.89  Aligned_cols=105  Identities=19%  Similarity=0.265  Sum_probs=67.3  Template_Neff=10.900

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|..++. +.++.++..|+.+|..+.....         .  ....+..++..+ .+.+..++..++.+|..+...
T Consensus       259 ~~~~~L~~~l~-~~~~~vr~~a~~~L~~l~~~~~---------~--~~~~~~~l~~~l~~~~~~~vr~~al~~L~~l~~~  326 (968)
T 5A1V_G          259 RFIRCIYNLLQ-SSSPAVKYEAAGTLVTLSSAPT---------A--IKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEH  326 (968)
T ss_dssp             HHHHHHHHSCC-SSSCSSCCTTHHHHTGGGCSTH---------H--HHHHHHHHHHHHHCCCCCCTTCCCCSCSSSSCSC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHhCCCHH---------H--HHHHHHHHHHHHHhcCChHHHHHHHHHHHHHhhC
Confidence            35666777777 4667788888888887765311         0  123455566666 566778888999999988753


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      +.....+ ..+++.+...+.+      .+..++..++.+|..+..
T Consensus       327 ~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~al~~L~~l~~  364 (968)
T 5A1V_G          327 PAHERVL-QDLVMDILRVLST------PDLEVRKKTLQLALDLVS  364 (968)
T ss_dssp             CSSCSSC-SHHHHHHTSCSSS------SCHHHHHHHHHHHHHHSS
T ss_pred             cchHHHH-HHHHHHHHHHhCC------CCHHHHHHHHHHHHHHcC
Confidence            2211111 2345556666655      356788888888888765


No 338
>3TJZ_B ADP-ribosylation factor 1, Coatomer subunit; protein trafficking, Golgi membrane, protein; HET: GNP; 2.9A {Saccharomyces cerevisiae}
Probab=86.96  E-value=0.036  Score=52.53  Aligned_cols=16  Identities=25%  Similarity=-0.029  Sum_probs=8.2  Template_Neff=12.100

Q NP_000290.2     697 SPKAAEAARLLLSDMW  712 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~  712 (747)
                      ++.++..++.+|..+.
T Consensus       225 ~~~~~~~~~~~l~~~~  240 (355)
T 3TJZ_B          225 SPFAYCMMIRVASRQL  240 (355)
T ss_pred             CHHHHHHHHHHHHHhC
Confidence            4445555555555544


No 339
>2IW3_B ELONGATION FACTOR 3A; ACETYLATION, ATP-BINDING, ELONGATION FACTOR, PROTEIN; HET: MSE, ADP, SO4; 2.4A {SACCHAROMYCES CEREVISIAE}
Probab=86.93  E-value=0.037  Score=61.15  Aligned_cols=151  Identities=9%  Similarity=0.010  Sum_probs=98.6  Template_Neff=11.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|+..+. +.++.++..++.++..+......     .... ....+++.+...+.+.++.++..++.+|..++...
T Consensus        54 ~~~~~l~~~l~-~~~~~~~~~~~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~d~~~~vr~~a~~~L~~l~~~~  126 (986)
T 2IW3_B           54 HFFGELAKGIK-DKKTAANAMQAVAHIANQSNLSP-----SVEP-YIVQLVPAICTNAGNKDKEIQSVASETLISIVNAV  126 (986)
T ss_dssp             HHHHHHHHHHT-STTTHHHHHHHHHHHSCTTTCCT-----TTHH-HHHTTHHHHHHHTTCSSHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHhhc-CHHHHHHHHHHHHHHHHhccCCc-----chHH-HHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHhc
Confidence            35666777776 35566676777777766643221     1111 12356777788888788889999999999887652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLL-TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL-~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ....  ...+++.+...+ .+      .++.++..++.+|..++...+....... ..+++.|..++.+. +..++..|+
T Consensus       127 ~~~~--~~~~l~~l~~~l~~~------~~~~vr~~al~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~d~-~~~vr~~a~  196 (986)
T 2IW3_B          127 NPVA--IKALLPHLTNAIVET------NKWQEKIAILAAFSAMVDAAKDQVALRM-PELIPVLSETMWDT-KKEVKAAAT  196 (986)
T ss_dssp             CGGG--HHHHHHHHHHHHHHC------CCHHHHHHHHHHHHHHHHHSHHHHHHHH-HHHHHHHHHHTTCS-CHHHHHHHH
T ss_pred             CHHH--HHHHHHHHHHHHhhc------CCHHHHHHHHHHHHHHHHHCHHHHHhhH-HHHHHHHHHhcCcC-CHHHHHHHH
Confidence            2111  224566677777 44      3678889999999988865332221111 34677788888766 778999999


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..++..
T Consensus       197 ~~l~~l~~~  205 (986)
T 2IW3_B          197 AAMTKATET  205 (986)
T ss_dssp             HHHHHHGGG
T ss_pred             HHHHHHHHh
Confidence            999888764


No 340
>5NZR_B Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=86.79  E-value=0.04  Score=61.63  Aligned_cols=105  Identities=19%  Similarity=0.265  Sum_probs=67.8  Template_Neff=10.900

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|..++. +.++.++..|+.+|..+.....         .  ....+..++..+ .+.+..++..++.+|..+...
T Consensus       259 ~~~~~L~~~l~-~~~~~vr~~a~~~L~~l~~~~~---------~--~~~~~~~l~~~l~~~~~~~vr~~al~~L~~l~~~  326 (968)
T 5NZR_B          259 RFIRCIYNLLQ-SSSPAVKYEAAGTLVTLSSAPT---------A--IKAAAQCYIDLIIKESDNNVKLIVLDRLVELKEH  326 (968)
T ss_dssp             HHHHHHHHHTS-CCSHHHHHHHHHHHHHHCCCHH---------H--HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHTCC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHhCCCHH---------H--HHHHHHHHHHHHHhcCChHHHHHHHHHHHHHhhC
Confidence            35667777777 4667788888888887765311         0  123455566666 566788899999999988753


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ......+ ..+++.+...+.+      .+..++..++.+|..+..
T Consensus       327 ~~~~~~~-~~~~~~l~~~l~~------~~~~vr~~al~~L~~l~~  364 (968)
T 5NZR_B          327 PAHERVL-QDLVMDILRVLST------PDLEVRKKTLQLALDLVS  364 (968)
T ss_dssp             TTCCHHH-HHHHHHHHHGGGS------CCHHHHHHHHHHHHTTCS
T ss_pred             cchHHHH-HHHHHHHHHHhCC------CCHHHHHHHHHHHHHHcC
Confidence            2211111 2345556666655      356788888888888765


No 341
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=86.78  E-value=0.037  Score=55.91  Aligned_cols=142  Identities=14%  Similarity=0.108  Sum_probs=93.4  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.++.++..++.+|..+....+.        .  ...+++.+...+.+.++.++..|+.+|..+.....
T Consensus        66 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  134 (600)
T 4P6Z_B           66 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKI  134 (600)
T ss_pred             hHHHHHHhcc-CCCHHHHHHHHHHHHHhccCCHh--------H--HHHHHHHHHHHccCCCHHHHHHHHHHHhcCCchHH
Confidence            4455666666 46677888888888877653221        1  12355666667777788888889888888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+..   +....+++.+...+.+. ++.++..++.+
T Consensus       135 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~~~  199 (600)
T 4P6Z_B          135 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQL---VEDQGFLDTLKDLISDS-NPMVVANAVAA  199 (600)
T ss_pred             -----HHHHHHHHHHhcCC------CCHHHHHHHHHHHHHHHhhChHH---hhccChHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 12345556666655      36788899999999887643221   11234567777777766 77888999998


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       200 l~~l~~~~  207 (600)
T 4P6Z_B          200 LSEIAESH  207 (600)
T ss_pred             HHHHHhhC
Confidence            88887653


No 342
>5VCH_A Kap123; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.35A {Kluyveromyces lactis}
Probab=86.69  E-value=0.038  Score=60.48  Aligned_cols=153  Identities=11%  Similarity=0.110  Sum_probs=80.3  Template_Neff=12.900

Q NP_000290.2     550 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH-PL  627 (747)
Q Consensus       550 ~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~-~e  627 (747)
                      +.+...+. +.++.++..++.++..++.....      ... ....+++.++..+ .+.++.++..++.++..+... +.
T Consensus       869 ~~l~~~~~-~~~~~~r~~~~~~l~~l~~~~~~------~~~-~~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~  940 (1116)
T 5VCH_A          869 PVILQLCQ-SKSKNKRSFAVGALSEIALGMRD------ENP-FIQELLEALIISLTNDKSLEVRCNASYGVGLLIEYSSF  940 (1116)
T ss_dssp             HHHHHHTT-CSCHHHHHHHHHHHHHHHHHHGG------GCT-THHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCCS
T ss_pred             HHHHHHcC-CCCHHHHHHHHHHHHHHHHhCCC------Cch-hHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHhCCc
Confidence            33444443 24456677777777777653221      111 1134555555553 345678888999999888765 21


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGN----------TSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~----------~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      . ...+ ..+++.+...+......          ......++..++.+|+.+....+...   .-..+++.++..+....
T Consensus       941 ~~~~~~-~~il~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~---~~~~~l~~~~~~l~~~~ 1016 (1116)
T 5VCH_A          941 DVSAIY-SPVLKSLYEILSVADEKNLATEDDEATKEIVDRTFSNVCGCVARMILKHQNLV---PLEHTIPALLSHLPFNT 1016 (1116)
T ss_dssp             CCHHHH-HHHHHHHHHHHHHHHHHHHSCSSCHHHHHHHHHHHHHHHHHHHHHHHHCGGGS---CHHHHHHHHHTTCSCSS
T ss_pred             chhhhH-HHHHHHHHHHhcchhHhccCCCCchhhHHHHHHHHHHHHHHHHHHHHHCcccC---CHHHHHHHHHhcCCCCC
Confidence            1 1111 23555565555421000          00245667788888888876533211   11234555555553221


Q NP_000290.2     697 SPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d~eVr~aAL~aLsnL~~~  714 (747)
                      +...+..++.+|..+...
T Consensus      1017 ~~~~~~~~~~~l~~l~~~ 1034 (1116)
T 5VCH_A         1017 AFEEYDPIFKLFLKLFQE 1034 (1116)
T ss_dssp             CGGGHHHHHHHHHHHHHT
T ss_pred             chhhhHHHHHHHHHHHHh
Confidence            455666677777666653


No 343
>6BCU_A mTOR, Target of rapamycin complex; PIKK, TRANSFERASE; HET: ATP, GTP; 3.43A {Homo sapiens}
Probab=86.66  E-value=0.04  Score=67.95  Aligned_cols=131  Identities=8%  Similarity=0.114  Sum_probs=72.7  Template_Neff=11.600

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-L  627 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e  627 (747)
                      ++.|...+.+.....++..++.+|..++.....     ....+ -..+++.+...+.+.++.++..++.+|+.++... .
T Consensus       952 ~~~l~~~l~~~~~~~~~~~a~~~l~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~ 1025 (2549)
T 6BCU_A          952 MVALMRIFRDQSLSHHHTMVVQAITFIFKSLGL-----KCVQF-LPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKS 1025 (2549)
T ss_dssp             HHHHHHHCSSTTHHHHHHHHHHHHHHHHHHHTT-----GGGGG-HHHHHHHHHHHHHHSCHHHHHHHHHHHHHHHHHHGG
T ss_pred             HHHHHHHHcCCChHHHHHHHHHHHHHHHHHcCc-----chHHh-HHHHHHHHHHHHhcCCHHHHHHHHHHHHHHHHHHHH
Confidence            555666665222345777888888888764321     11111 2456777778887777788888999998887541 1


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS  694 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s  694 (747)
                      . ..+. ..+++.+..++..       ...++..++.+|..++........... ..+++.++..+.+
T Consensus      1026 ~~~~~~-~~i~~~l~~~~~~-------~~~v~~~~~~~l~~l~~~~~~~~~~~~-~~l~~~l~~~l~~ 1084 (2549)
T 6BCU_A         1026 HIRPYM-DEIVTLMREFWVM-------NTSIQSTIILLIEQIVVALGGEFKLYL-PQLIPHMLRVFMH 1084 (2549)
T ss_dssp             GGGGGH-HHHHHHHHHTCCS-------CHHHHHHHHHHHHHHHHHHGGGGGGTH-HHHHHHHHHHHHS
T ss_pred             hcHHhH-HHHHHHHHHHHhc-------CHHHHHHHHHHHHHHHHHhcHhhHhHH-HHHHHHHHHHHhc
Confidence            1 1111 2234444444433       244677788888887654222111111 2345555555543


No 344
>6BCX_B mTOR, Target of rapamycin complex; PIKK, TRANSFERASE; HET: ATP; 3.0A {Homo sapiens}
Probab=86.66  E-value=0.04  Score=67.95  Aligned_cols=131  Identities=8%  Similarity=0.114  Sum_probs=72.7  Template_Neff=11.600

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-L  627 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-e  627 (747)
                      ++.|...+.+.....++..++.+|..++.....     ....+ -..+++.+...+.+.++.++..++.+|+.++... .
T Consensus       952 ~~~l~~~l~~~~~~~~~~~a~~~l~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~ 1025 (2549)
T 6BCX_B          952 MVALMRIFRDQSLSHHHTMVVQAITFIFKSLGL-----KCVQF-LPQVMPTFLNVIRVCDGAIREFLFQQLGMLVSFVKS 1025 (2549)
T ss_pred             HHHHHHHHcCCChHHHHHHHHHHHHHHHHHcCc-----chHHh-HHHHHHHHHHHHhcCCHHHHHHHHHHHHHHHHHHHH
Confidence            555666665222345777888888888764321     11111 2456777778887777788888999998887541 1


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRS  694 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s  694 (747)
                      . ..+. ..+++.+..++..       ...++..++.+|..++........... ..+++.++..+.+
T Consensus      1026 ~~~~~~-~~i~~~l~~~~~~-------~~~v~~~~~~~l~~l~~~~~~~~~~~~-~~l~~~l~~~l~~ 1084 (2549)
T 6BCX_B         1026 HIRPYM-DEIVTLMREFWVM-------NTSIQSTIILLIEQIVVALGGEFKLYL-PQLIPHMLRVFMH 1084 (2549)
T ss_pred             hcHHhH-HHHHHHHHHHHhc-------CHHHHHHHHHHHHHHHHHhcHhhHhHH-HHHHHHHHHHHhc
Confidence            1 1111 2234444444433       244677788888887654222111111 2345555555543


No 345
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=86.43  E-value=0.045  Score=64.20  Aligned_cols=110  Identities=15%  Similarity=0.148  Sum_probs=59.4  Template_Neff=9.800

Q NP_000290.2     249 KAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ  328 (747)
Q Consensus       249 ~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~  328 (747)
                      .+...+.+.+..++..++.+|..++..........+...++..+...+.+.+..++..++.+|..++.............
T Consensus       935 ~L~~~L~~~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~~~~l~~~l~ 1014 (1304)
T 5IFE_C          935 TVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIK 1014 (1304)
T ss_pred             HHHHHhcCCCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhChHHhcccHH
Confidence            33344445566777778888877765322111111112345556666665566777777777777764432111001112


Q NP_000290.2     329 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       329 ~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      .+++.+...+. ..+..++..++.++..++.
T Consensus      1015 ~ll~~L~~~L~-~~~~~Vr~~ai~~L~~i~~ 1044 (1304)
T 5IFE_C         1015 DLLPRLTPILK-NRHEKVQENCIDLVGRIAD 1044 (1304)
T ss_pred             hHHHHHHHHhC-CCCHHHHHHHHHHHHHHHh
Confidence            35555666665 4455667777777776665


No 346
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=86.43  E-value=0.045  Score=64.20  Aligned_cols=110  Identities=15%  Similarity=0.148  Sum_probs=59.4  Template_Neff=9.800

Q NP_000290.2     249 KAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETRRQ  328 (747)
Q Consensus       249 ~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll~~  328 (747)
                      .+...+.+.+..++..++.+|..++..........+...++..+...+.+.+..++..++.+|..++.............
T Consensus       935 ~L~~~L~~~~~~vR~~A~~~L~~l~~~~~~~~~~~~~~~l~~~L~~~L~d~~~~vr~~al~aL~~l~~~~~~~~l~~~l~ 1014 (1304)
T 6AHD_1          935 TVLWRLNNKSAKVRQQAADLISRTAVVMKTCQEEKLMGHLGVVLYEYLGEEYPEVLGSILGALKAIVNVIGMHKMTPPIK 1014 (1304)
T ss_pred             HHHHHhcCCCHHHHHHHHHHHHHHHHhccCcCHHHHHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhhChHHhcccHH
Confidence            33344445566777778888877765322111111112345556666665566777777777777764432111001112


Q NP_000290.2     329 NGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       329 ~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                      .+++.+...+. ..+..++..++.++..++.
T Consensus      1015 ~ll~~L~~~L~-~~~~~Vr~~ai~~L~~i~~ 1044 (1304)
T 6AHD_1         1015 DLLPRLTPILK-NRHEKVQENCIDLVGRIAD 1044 (1304)
T ss_pred             hHHHHHHHHhC-CCCHHHHHHHHHHHHHHHh
Confidence            35555666665 4455667777777776665


No 347
>6LTJ_L Histone H3.2, Histone H4, Histone; Chromatin remodeler, Complex, GENE REGULATION; 3.7A {Xenopus laevis}
Probab=86.40  E-value=0.056  Score=63.52  Aligned_cols=152  Identities=14%  Similarity=0.061  Sum_probs=89.3  Template_Neff=5.100

Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-----NSD----------VVRSGASLLSNMSRHPL  627 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-----d~e----------Vr~~AL~aLsnLa~~~e  627 (747)
                      .+++.++.+|.+|+....-  .. ....+ ...++..|+.++...     ++.          .+..|+.+|+.|+..+.
T Consensus      1065 ~LRenaLviLaNIAg~LdL--s~-~~e~I-~~~ild~LLhwlv~~sa~a~Dp~~~~~~~~~lSp~~lALEaLsKLsv~d~ 1140 (1295)
T 6LTJ_L         1065 MLRENTLVTLANISGQLDL--SP-YPESI-CLPVLDGLLHWAVCPSAEAQDPFSTLGPNAVLSPQRLVLETLSKLSIQDN 1140 (1295)
T ss_dssp             HHHHHHHHHHHHHGGGCCC--SS-SCHHH-HHHHHHHHHHHHHCCSSSSSSCCTTSCTTCCCCHHHHHHHHHHHHHTSHH
T ss_pred             HHHHHHHHHHHHHHcccCC--CC-CChHh-HHHHHHHHHHHHcCcChhcCChhhccCCCCCCCHHHHHHHHHHHHhCCCc
Confidence            4566788888888764220  00 01111 112455555554321     111          12348899999987643


Q NP_000290.2     628 LH-RVMG-------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK-QYFSSSMLNNIINLCRSSA--  696 (747)
Q Consensus       628 ~~-~ll~-------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~-~Lve~giL~~Ll~LL~s~~--  696 (747)
                      +. .++.       ..++..|+.+|...     .+..+++.++.+|.+|+........ ...+.+.+..|+.+|+...  
T Consensus      1141 N~dlLlat~p~srle~Ll~~LV~lL~~~-----ed~~lrE~AL~lL~~Ls~~~~~~ar~ia~~~g~I~~LV~fLE~~~~~ 1215 (1295)
T 6LTJ_L         1141 NVDLILATPPFSRLEKLYSTMVRFLSDR-----KNPVCREMAVVLLANLAQGDSLAARAIAVQKGSIGNLLGFLEDSLAA 1215 (1295)
T ss_dssp             HHHHHHTSSCHHHHHHHHHHHHHHHHHC-----SSHHHHHHHHHHHHHHHHHCHHHHHHHHTSTTHHHHHHHHHHHHHHH
T ss_pred             hHHHHHhCCCHHHHHHHHHHHHHHhcCC-----CCHHHHHHHHHHHHHHHcCCHHHHHHHHHhcCHHHHHHHHHHHHHHH
Confidence            32 2222       23566677777652     2456788999999999875433322 3334567888888876430  


Q NP_000290.2     697 ---------------------SPKAAEAARLLLSDMWSSKELQGVLRQ  723 (747)
Q Consensus       697 ---------------------d~eVr~aAL~aLsnL~~~~~~~~~~~~  723 (747)
                                           ...+++.|+.+|..|+...+-...+.+
T Consensus      1216 ~~~~~~~~~~~~~~npe~~gtS~~m~rRAA~aL~~La~vp~NR~~F~~ 1263 (1295)
T 6LTJ_L         1216 TQFQQSQASLLHMQNPPFEPTSVDMMRRAARALLALAKVDENHSEFTL 1263 (1295)
T ss_dssp             HHHCC--------------CCCSHHHHHHHHHHHHHHTTSSSHHHHTT
T ss_pred             HHHHHHHHHHHHhhCCCCCCCCHHHHHHHHHHHHHHhcChhhHHHHHH
Confidence                                 134567788899999887777776665


No 348
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=86.18  E-value=0.043  Score=55.49  Aligned_cols=139  Identities=17%  Similarity=0.118  Sum_probs=92.2  Template_Neff=12.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .+..++..+. +.+..++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        63 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  131 (585)
T 6CRI_R           63 GQLECLKLIA-SQKFTDKRIGYLGAMLLLDERQD--------V--HLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEM  131 (585)
T ss_pred             HHHHHHHHHh-CCCchHHHHHHHHHHHhCCCChH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHhhCCHHH
Confidence            3455666776 46777888888888887754221        1  12345666777777778888888888887764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+...     ...++.+...+.+. ++.++..++.+
T Consensus       132 -----~~~~~~~l~~~l~~------~~~~vr~~a~~~L~~~~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~  194 (585)
T 6CRI_R          132 -----CRDLAGEVEKLLKT------SNSYLRKKAALCAVHVIRKVPELM-----EMFLPATKNLLNEK-NHGVLHTSVVL  194 (585)
T ss_pred             -----HHHHHHHHHHHHhC------CChHHHHHHHHHHHHHHHHCHHHH-----HHHHHHHHHHHcCC-CHHHHHHHHHH
Confidence                 11345556666665      367888899999998876432221     24566777777665 77888888888


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      |..+...
T Consensus       195 l~~l~~~  201 (585)
T 6CRI_R          195 LTEMCER  201 (585)
T ss_pred             HHHHHHh
Confidence            8887643


No 349
>5DFZ_B Vacuolar protein sorting-associated protein 38; Vps34, Vps15, Vps30, Vps38, Autophagy; 4.4A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=85.86  E-value=0.051  Score=64.44  Aligned_cols=292  Identities=12%  Similarity=0.004  Sum_probs=157.7  Template_Neff=9.900

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQ-AIGAYYIQHTCFQDESA--KQQVYQLGGICKLVDLL---RSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr-~sAL~aLsnLs~~~~~~--~~~li~~~IL~~Ll~lL---~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      .+++.|+..+.+.+..++ ..++..|..+.......  ........+++.|+.++   .+.++.++..+..+|..+....
T Consensus       464 ~~i~~L~~~l~d~~~~vR~~~a~~~L~~l~~~~~~~~~~~~~~~~~~lp~Li~~L~~~~d~~~~vr~~aa~~l~~~~~~~  543 (1460)
T 5DFZ_B          464 RVVPYFVCCFEDSDQDVQALSLLTLIQVLTSVRKLNQLNENIFVDYLLPRLKRLLISNRQNTNYLRIVFANCLSDLAIII  543 (1460)
T ss_pred             cchHHHHHHhcCCCHHHHHHHHHHHHHHhcCCCCccCCccccCcCChHHHHHHHHHhccCCCHHHHHHHHHHHHHHHHHc
Confidence            455667777777788889 89999998886543211  11223345678888888   7777888888888887774321


Q NP_000290.2     319 TTN------------KLETRRQNGIREAVSL----LRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRVIIP  382 (747)
Q Consensus       319 ~~~------------~~~ll~~~IL~~Ll~l----L~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL~~~  382 (747)
                      ...            .........++.+..+    +. +.++.++..++.+|..+........ ....+++.|+.+|..+
T Consensus       544 ~~~~l~~l~~~~~~~~~~~l~~~~~~~l~~ll~~~l~-d~~~~VR~~A~~aL~~l~~~~~~~~-~~~~~l~~Li~ll~d~  621 (1460)
T 5DFZ_B          544 NRFQEFTFAQHCNDNSSTKYSAKLIQSVEDLTVSFLT-DNDTYVKMALLQNILPLCKFFGRER-TNDIILSHLITYLNDK  621 (1460)
T ss_pred             CHHHHHHHHHhcccChhHHHHcChHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHhccccccc-cHHhHHHHHHHHhcCC
Confidence            100            0001111223333333    33 4567889999999988876422111 1135666677766321


Q NP_000290.2     383 FSGWCDGNSNMSREVVDPEVFFNATGCLRKRLGMRELLALVPQRATSSRVNLSSADAGRQTMRNYSGLIDSLMAYVQNCV  462 (747)
Q Consensus       383 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  462 (747)
                                      +++|-.+|..+|.+--.      .++               ....+   ..++..|...+.   
T Consensus       622 ----------------~~~VR~~a~~aL~~i~~------~~~---------------~~~~~---~~~i~~L~~~l~---  658 (1460)
T 5DFZ_B          622 ----------------DPALRVSLIQTISGISI------LLG---------------TVTLE---QYILPLLIQTIT---  658 (1460)
T ss_pred             ----------------CHHHHHHHHHHHHHHHh------hcC---------------chhhc---hhHHHHHHHHhc---
Confidence                            35555566666543110      000               00000   011222222111   


Q NP_000290.2     463 AASRCDDKSVENCMCVLHNLSYRLDAEVPTRYRQLEYNARNAYTEKSSTGCFSNKSDKMMNNNYDCPLPEEETNPKGSGW  542 (747)
Q Consensus       463 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ni~~~~~  542 (747)
                            |..                .+|  |     .+|-.+.      +.+..                 ..+..  . 
T Consensus       659 ------d~~----------------~~v--R-----~~a~~aL------~~~~~-----------------~~~~~--~-  683 (1460)
T 5DFZ_B          659 ------DSE----------------ELV--V-----ISVLQSL------KSLFK-----------------TGLIR--K-  683 (1460)
T ss_pred             ------CCC----------------HHH--H-----HHHHHHH------HHhcC-----------------Ccchh--h-
Confidence                  110                000  0     0111111      00000                 00000  0 


Q NP_000290.2     543 LYHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNM  622 (747)
Q Consensus       543 lve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnL  622 (747)
                      ....++++.|..++. +.++.++..|+.+|..+......      . . ....+++.|+.+|.++++.++..|+.+|..+
T Consensus       684 ~~~~~~i~~l~~~l~-d~~~~VR~~A~~al~~l~~~~~~------~-~-~~~~~l~~L~~~l~d~~~~vr~~a~~aL~~~  754 (1460)
T 5DFZ_B          684 KYYIDISKTTSPLLL-HPNNWIRQFTLMIIIEIINKLSK------A-E-VYCILYPIIRPFFEFDVEFNFKSMISCCKQP  754 (1460)
T ss_pred             cccchhHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCC------H-H-HHHHHHHHHHHHhcCCCHHHHHHHHHHhCCC
Confidence            001246778888888 57889999999999988764221      1 1 1246788899999999999999999999998


Q NP_000290.2     623 SRHPLLH----RVMGNQVFPEVTRLLT  645 (747)
Q Consensus       623 a~~~e~~----~ll~~giI~~Ll~LL~  645 (747)
                      .......    ..+..+.+..+..++.
T Consensus       755 ~~~~~~~~~~~~~~~~~~~~~~~~~~~  781 (1460)
T 5DFZ_B          755 VSRSVYNLLCSWSVRASKSLFWKKIIT  781 (1460)
T ss_pred             CCHHHHHHHHHHHHHhchhHHHHHHHH
Confidence            7763331    2244455555555554


No 350
>2QNA_A Importin subunit beta-1, Snurportin-1; Nuclear transport, import of spliceosomal; HET: SO4; 2.84A {Homo sapiens}
Probab=85.76  E-value=0.046  Score=56.33  Aligned_cols=154  Identities=11%  Similarity=0.064  Sum_probs=95.8  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQS--GNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s--~d~eVr~~AL~aLsnLa  623 (747)
                      .++.|+..+. +.+  ..++..++.+|..++...+.   . .... ....+++.+...+.+  .++.++..++.+|..++
T Consensus         4 l~~~l~~~l~-~~~~~~~~~~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~~~vr~~a~~~l~~l~   77 (762)
T 2QNA_A            4 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL   77 (762)
T ss_pred             hHHHHHHHhc-CCCCCHHHHHHHHHHHHHHHHhCCH---h-hcHH-HHHhHHHHHHHHhcCCCCCHHHHHHHHHHHHHHH
Confidence            4566777776 344  67888899999888764221   0 0111 113456677777764  35788999999999988


Q NP_000290.2     624 RHP-LL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~-e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ... .. . ......+++.+...+.+      .++.++..++.+|..++..............+++.+...+.+. ++.+
T Consensus        78 ~~~~~~~~~~~~~~~i~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~~~~~-~~~v  150 (762)
T 2QNA_A           78 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  150 (762)
T ss_pred             hcCCccCCcchhHHhHHHHHHHHhCC------CCHHHHHHHHHHHHHHHHhCchhhHHhhHHhHHHHHHHHcCCC-CHHH
Confidence            652 11 1 01122345555566654      3678888999999988764332222222223566666677655 7788


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       151 ~~~a~~~l~~l~~~  164 (762)
T 2QNA_A          151 ALQGIEFWSNVCDE  164 (762)
T ss_pred             HHHHHHHHHHHHhc
Confidence            88888888887754


No 351
>3WOZ_C CLIP-associating protein 2; HEAT Repeat, Microtubule binding, Tubulin; HET: MSE; 2.2A {Mus musculus}
Probab=85.74  E-value=0.049  Score=48.60  Aligned_cols=154  Identities=11%  Similarity=0.036  Sum_probs=91.0  Template_Neff=11.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.++..+. +.++..|..++..|..++.....   . ....  -..++..+...+.+.+..++..++.++..++.. 
T Consensus         5 ~~~~~~~~~l~-~~~w~~R~~al~~l~~~~~~~~~---~-~~~~--~~~i~~~l~~~l~d~~~~v~~~al~~l~~l~~~~   77 (232)
T 3WOZ_C            5 EDVAEVLNRCA-SSNWSERKEGLLGLQNLLKNQRT---L-SRIE--LKRLCEIFTRMFADPHGKVFSMFLETLVDFIQVH   77 (232)
T ss_dssp             CCHHHHHHHHT-CSSHHHHHHHHHHHHHHHHTTCC---C-CHHH--HHHHHHHHHHHTTCCCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHh-CCCHHHHHHHHHHHHHHHhcCcc---c-CHHH--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHc
Confidence            45666777777 47888899999999888864221   0 0111  135666777777777888999999999988865 


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ..........+++.++..+.+.     ....++..+..+|..+....+.  ..++ ..+++.+...+.+. ++.++..++
T Consensus        78 ~~~~~~~~~~ll~~ll~~l~d~-----~~~~vr~~a~~~l~~i~~~~~~--~~~~-~~l~~~l~~~~~~~-~~~~r~~~l  148 (232)
T 3WOZ_C           78 KDDLQDWLFVLLTQLLKKMGAD-----LLGSVQAKVQKALDITRESFPN--DLQF-NILMRFTVDQTQTP-SLKVKVAIL  148 (232)
T ss_dssp             GGGCTTTHHHHHHHHHHHTTTT-----CCHHHHHHHHHHHHHHHHHSCH--HHHH-HHHHHHHTCTTCCC-CHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHhccc-----cCHHHHHHHHHHHHHHHHHCCc--chHH-HHHHHHhhccccCC-CHHHHHHHH
Confidence            2111111123555566555441     1456788888888887543211  1111 12233333344433 567777777


Q NP_000290.2     706 LLLSDMWSSKE  716 (747)
Q Consensus       706 ~aLsnL~~~~~  716 (747)
                      .++..++...+
T Consensus       149 ~~l~~l~~~~~  159 (232)
T 3WOZ_C          149 KYIETLAKQMD  159 (232)
T ss_dssp             HHHHHHHTTSC
T ss_pred             HHHHHHHHhcC
Confidence            77777665533


No 352
>3WOZ_D CLIP-associating protein 2; HEAT Repeat, Microtubule binding, Tubulin; HET: MSE; 2.2A {Mus musculus}
Probab=85.74  E-value=0.049  Score=48.60  Aligned_cols=154  Identities=11%  Similarity=0.036  Sum_probs=91.0  Template_Neff=11.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.++..+. +.++..|..++..|..++.....   . ....  -..++..+...+.+.+..++..++.++..++.. 
T Consensus         5 ~~~~~~~~~l~-~~~w~~R~~al~~l~~~~~~~~~---~-~~~~--~~~i~~~l~~~l~d~~~~v~~~al~~l~~l~~~~   77 (232)
T 3WOZ_D            5 EDVAEVLNRCA-SSNWSERKEGLLGLQNLLKNQRT---L-SRIE--LKRLCEIFTRMFADPHGKVFSMFLETLVDFIQVH   77 (232)
T ss_dssp             CCHHHHHHHHH-CSCHHHHHHHHHHHHHHHHTTCC---C-CHHH--HHHHHHHHHHHTTCCCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHh-CCCHHHHHHHHHHHHHHHhcCcc---c-CHHH--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHc
Confidence            45666777777 47888899999999888864221   0 0111  135666777777777888999999999988865 


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      ..........+++.++..+.+.     ....++..+..+|..+....+.  ..++ ..+++.+...+.+. ++.++..++
T Consensus        78 ~~~~~~~~~~ll~~ll~~l~d~-----~~~~vr~~a~~~l~~i~~~~~~--~~~~-~~l~~~l~~~~~~~-~~~~r~~~l  148 (232)
T 3WOZ_D           78 KDDLQDWLFVLLTQLLKKMGAD-----LLGSVQAKVQKALDITRESFPN--DLQF-NILMRFTVDQTQTP-SLKVKVAIL  148 (232)
T ss_dssp             GGGCGGGHHHHHHHHHHHTTSC-----CCHHHHHHHHHHHHHHHHHSCH--HHHH-HHHHHHHTCSSCCC-CHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHhccc-----cCHHHHHHHHHHHHHHHHHCCc--chHH-HHHHHHhhccccCC-CHHHHHHHH
Confidence            2111111123555566555441     1456788888888887543211  1111 12233333344433 567777777


Q NP_000290.2     706 LLLSDMWSSKE  716 (747)
Q Consensus       706 ~aLsnL~~~~~  716 (747)
                      .++..++...+
T Consensus       149 ~~l~~l~~~~~  159 (232)
T 3WOZ_D          149 KYIETLAKQMD  159 (232)
T ss_dssp             HHHHHHHTTCC
T ss_pred             HHHHHHHHhcC
Confidence            77777665533


No 353
>5DCQ_C artificial repeat proteins (alphaREP3), Fibronectin-binding; adhesin, artificial repeat proteins, complex; HET: FMT; 1.83A {synthetic construct}
Probab=85.49  E-value=0.051  Score=45.36  Aligned_cols=47  Identities=15%  Similarity=0.166  Sum_probs=25.2  Template_Neff=12.100

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      ++.++..++.+|..+...           ..++.+..++.+. +..++..++.++..+.
T Consensus       120 ~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~  166 (170)
T 5DCQ_C          120 DSDVRRTAAYALGEIGGE-----------RVRAAMEKLAETG-TGFARKVAVNYLETHK  166 (170)
T ss_dssp             SHHHHHHHHHHHHHHCHH-----------HHHHHHHHHHHHC-CHHHHHHHHHHHHTC-
T ss_pred             CHHHHHHHHHHHHHhchH-----------HHHHHHHHHHHcC-ChHHHHHHHHHHHhcc
Confidence            455666666666555431           1344444555544 5566666766666543


No 354
>4L7M_A Putative uncharacterized protein; HEAT-repeats, Hypothetical, UNKNOWN FUNCTION; HET: MSE, GOL; 2.002A {Thermococcus onnurineus}
Probab=85.26  E-value=0.051  Score=48.13  Aligned_cols=143  Identities=17%  Similarity=0.105  Sum_probs=85.7  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+...  .          .....++.+..++.+.++.++..++.++..++....
T Consensus       120 ~~~~l~~~l~-~~~~~~~~~a~~~l~~~~~~--~----------~~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~  186 (269)
T 4L7M_A          120 AAKTLVSLLE-SPDDMMRIETIDVLSKLQPL--E----------DSKLVRTYINELVVSPDLYTKVAGFCLFLNMLNSSA  186 (269)
T ss_dssp             HHHHHHHHTT-SCCHHHHHHHHHHHTTCCBS--C----------CCHHHHHHHHHHHHCSSHHHHHHHHHHHHHHGGGCS
T ss_pred             HHHHHHHHcC-CCCHHHHHHHHHHHHhcCCh--h----------HhhchHHHHHHHhcCCCHHHHHHHHHHHHHHHcCCC
Confidence            4556666666 35666777777777665321  0          123566777777877778889999999998875311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP-QLAKQYFSSSMLNNIINLCRS--SASPKAAEAA  704 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~-e~~~~Lve~giL~~Ll~LL~s--~~d~eVr~aA  704 (747)
                      ..... ..+++.+...+.+      .++.++..++.+|..+..... .......  +.+..++..+.+  . ++.++..+
T Consensus       187 ~~~~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~--~~~~~l~~~l~~~~~-~~~vr~~a  256 (269)
T 4L7M_A          187 DSGHL-TLILDEIPSLLQN------DNEFIVELALDVLEKALSFPLLENVKIEL--LKISRIVDGLVYREG-APIIRLKA  256 (269)
T ss_dssp             SCCCG-GGTTTTHHHHHTC------SCHHHHHHHHHHHHHHTTSCCCSCCHHHH--HHHHHHHHHHTTCSS-CHHHHHHH
T ss_pred             CcchH-HHHHHHHHHHHcC------CCHHHHHHHHHHHHHHcCCccHHHHHHHH--HHHHHHHhhccCCCC-CHHHHHHH
Confidence            11111 1245556666665      367888899999988875411 1111111  233344444443  3 67788888


Q NP_000290.2     705 RLLLSDMWS  713 (747)
Q Consensus       705 L~aLsnL~~  713 (747)
                      +.+|..+..
T Consensus       257 ~~~l~~l~~  265 (269)
T 4L7M_A          257 KKVSDLIDS  265 (269)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            888877653


No 355
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=85.10  E-value=0.053  Score=54.64  Aligned_cols=109  Identities=13%  Similarity=0.033  Sum_probs=65.8  Template_Neff=12.700

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+....+..........+++.+...+.+.+..++..++.++..+.......   
T Consensus       176 ~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~l~~~~~~~~~~---  252 (600)
T 4P6Z_B          176 GFLDTLKDLISDSNPMVVANAVAALSEIAESHPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDRE---  252 (600)
T ss_pred             ChHHHHHHHhcCCCHHHHHHHHHHHHHHHhhCCCcchhccCHHHHHHHHHHhhcCCHHHHHHHHHHHHHhCCCCHHH---
Confidence            35566666676777788888888888887643321111112245555666666556667777777777766432211   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ...++..+...+. +.++.++..++.++..+..
T Consensus       253 --~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~  284 (600)
T 4P6Z_B          253 --AQSICERVTPRLS-HANSAVVLSAVKVLMKFME  284 (600)
T ss_pred             --HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHH
Confidence              1234555555565 4566777788888777765


No 356
>5MU7_A Coatomer subunit beta, Coatomer subunit; coatomer, COPI, beta COP, delta; 2.57A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=85.09  E-value=0.053  Score=50.69  Aligned_cols=101  Identities=9%  Similarity=0.074  Sum_probs=54.4  Template_Neff=12.800

Q NP_000290.2     598 PQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK  677 (747)
Q Consensus       598 ~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~  677 (747)
                      +.+...+.+.++.++..++.+|..+......   ....+++.+...+.+      .+..++..++.+|..+... ..   
T Consensus       191 ~~l~~~l~~~~~~~~~~a~~~l~~~~~~~~~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~-~~---  257 (373)
T 5MU7_A          191 GTVFEGIPNAEELLQLVEIEFIRKDALHNPQ---NKPRYLRLIFDLLEA------NTSTVVYEAASSLTALTNN-PV---  257 (373)
T ss_dssp             HHTGGGGGGSCHHHHHHHHHHHHHHHHHCGG---GHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHCCC-HH---
T ss_pred             HHHHhcCCChhHHHHHHHHHHHHHHhccCcc---cHHHHHHHHHHHHhc------CCHHHHHHHHHHHHHcCCC-HH---
Confidence            3344444444444444455444444332100   012344555555544      2556677777777776542 11   


Q NP_000290.2     678 QYFSSSMLNNIINLCR-SSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       678 ~Lve~giL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~  714 (747)
                       .. ...++.+...+. +. ++.++..++.+|..+...
T Consensus       258 -~~-~~~~~~l~~~l~~~~-~~~vr~~a~~~l~~l~~~  292 (373)
T 5MU7_A          258 -AV-KAAAGKFIELAIKEA-DNNVKLIVLDRVDQLRQK  292 (373)
T ss_dssp             -HH-HHHHHHHHHHHHHCC-CHHHHHHHHHHHHHHHHH
T ss_pred             -HH-HHHHHHHHHHHhhCC-ChhHHHHHHHHHHHHHHh
Confidence             11 135666777776 44 778888888888888865


No 357
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=84.97  E-value=0.056  Score=55.88  Aligned_cols=142  Identities=13%  Similarity=0.105  Sum_probs=95.5  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. ++++.++..++.++..+....+.        .  ...+++.+...+.+.++.++..++.+++.+.....
T Consensus        50 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  118 (657)
T 4UQI_B           50 LFPDVVNCMQ-TDNLELKKLVYLYLMNYAKSQPD--------M--AIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKI  118 (657)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCHh--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHhhcCCchh
Confidence            4555666676 46677888888888887764221        1  13456667777777788889999999988864311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.+|..+....+..   +....+++.+..++.+. ++.++..++.+
T Consensus       119 -----~~~l~~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~d~-~~~vr~~a~~~  183 (657)
T 4UQI_B          119 -----TEYLCEPLRKCLKD------EDPYVRKTAAVCVAKLHDINAQM---VEDQGFLDSLRDLIADS-NPMVVANAVAA  183 (657)
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHH---hcCcchHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 12345556666655      36788899999999887643221   12234567777777766 77889999999


Q NP_000290.2     708 LSDMWSSK  715 (747)
Q Consensus       708 LsnL~~~~  715 (747)
                      |..+....
T Consensus       184 l~~l~~~~  191 (657)
T 4UQI_B          184 LSEISESH  191 (657)
T ss_pred             HHHHHhcC
Confidence            88887654


No 358
>6MZE_Z Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: MG, GTP, GDP; 3.6A {Sus scrofa}
Probab=84.94  E-value=0.055  Score=53.37  Aligned_cols=149  Identities=8%  Similarity=0.061  Sum_probs=96.3  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLM-GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL-~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +++.+...+ . +.++.++..++.++..++.....   . .... ....+++.+...+.+.+..++..++.+|..++...
T Consensus       340 ~~~~l~~~l~~-d~~~~v~~~a~~~l~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  413 (536)
T 6MZE_Z          340 YLRVLANVIQK-DANVQAVTIAANSVQLLCNSLRS---N-FTRS-YGAIVLVPLLERTKEKKPSVNEAICSALDAVATYC  413 (536)
T ss_dssp             THHHHHHHHHH-CSCHHHHHHHHHHHHHHHHHTTT---C-CSSH-HHHHHHHHHHHHTTCCCHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHhc-CchHHHHHHHHHHHHHHHHHccc---c-ccHH-HHHHHHHHHHHHhhccCHHHHHHHHHHHHHHHHhc
Confidence            556666776 5 46778888999999988764221   0 0101 12356677777777777788888988888887542


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA-------KQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~-------~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ..     ..+++.+...+.+      .++.++..++.+|..+........       ... ...+++.+...+.+. +..
T Consensus       414 ~~-----~~~~~~l~~~l~~------~~~~vr~~~l~~l~~~~~~~~~~~~~~~~~~~~~-~~~i~~~l~~~l~~~-~~~  480 (536)
T 6MZE_Z          414 GF-----DDCLEETLNYMKH------KTPQVRIECTKFLTRMLQGWKSDGPLQNQLLFKL-LPEVTTAVLKIVNDT-QPT  480 (536)
T ss_dssp             TT-----SSHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHTCCCCSSSCCHHHHTC-CCCCCHHHHHHHTCS-SHH
T ss_pred             CH-----HHHHHHHHHHHcc------CCHHHHHHHHHHHHHHHhcCCCCCchhhHHHHHH-HHHHHHHHHHHHcCC-CHH
Confidence            11     1244555555554      367788889999888876432210       011 123566677777765 778


Q NP_000290.2     700 AAEAARLLLSDMWSSK  715 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~~  715 (747)
                      ++..++.++..+....
T Consensus       481 vr~~a~~~l~~l~~~~  496 (536)
T 6MZE_Z          481 TRNTGFECFATLMKLV  496 (536)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHH
Confidence            9999999999888654


No 359
>4MFU_A Beta-catenin-like protein 1; ARM repeats, GENE REGULATION; 2.744A {Homo sapiens}
Probab=84.81  E-value=0.067  Score=56.37  Aligned_cols=117  Identities=12%  Similarity=0.116  Sum_probs=82.7  Template_Neff=8.700

Q NP_000290.2     610 DVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP---------QLAKQY  679 (747)
Q Consensus       610 eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~---------e~~~~L  679 (747)
                      .....++.+|.+|+..+.. ..++..++++.|+.+|.+      .+..+...++.+|.+|+....         .....+
T Consensus        42 ~~L~~ai~~L~~La~~p~~~~~lv~~g~i~~Lv~LL~~------~n~~i~~~a~~~L~~Lt~~~~~~~~~~~~~~~~~~l  115 (490)
T 4MFU_A           42 LDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGH------DNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDAL  115 (490)
T ss_dssp             HHHHHHHHHHHTTTTSCCCTHHHHHTTHHHHHHHHTSC------SSHHHHHHHHHHHHHHHHGGGSSCCCHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHhcCHHHHHHHHHCChHHHHHHHhCC------CCHHHHHHHHHHHHHHcCcccccCChhhHHHHHHHH
Confidence            3445678888888876544 455667889999999976      356788899999999987532         235566


Q NP_000290.2     680 FSSSMLNNIINLCRS------SASPKAAEAARLLLSDMWSSK-ELQGVLRQQGFDRNMLGT  733 (747)
Q Consensus       680 ve~giL~~Ll~LL~s------~~d~eVr~aAL~aLsnL~~~~-~~~~~~~~~~~~~~~~~~  733 (747)
                      .+.++++.|+.+|..      . +...+..++.+|.+|+... +....+.+.|+-..++..
T Consensus       116 ~~~g~l~~Lv~~L~~~~e~~~~-d~~~~~~al~~L~nL~~~~~~~~~~i~~~~~l~~Ll~~  175 (490)
T 4MFU_A          116 VDGQVVALLVQNLERLDESVKE-EADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKR  175 (490)
T ss_dssp             HHTTHHHHHHHHHHHCCTTCHH-HHHHHHHHHHHHHHHHHHSTTHHHHHCCCCCHHHHHHH
T ss_pred             HhCCHHHHHHHHHHhccccccc-hHHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHH
Confidence            677888889888875      3 5677889999999998754 444445555554444433


No 360
>5N3U_B Phycocyanobilin lyase subunit alpha (E.C.4.-.-.-); phycobilisome, chromophorylation, phycocyanin, lyase; 1.89A {Nostoc sp. PCC 7120}
Probab=84.57  E-value=0.06  Score=46.12  Aligned_cols=135  Identities=14%  Similarity=0.143  Sum_probs=82.4  Template_Neff=12.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      +.++.|...+. +.++.++..++.+|..+..                 ..++.+...+.+.++.++..++.+|..+... 
T Consensus        32 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~-----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~-   92 (208)
T 5N3U_B           32 AAIPTLIAVFG-YNNPTAAAIASTALVQLGE-----------------VAVPQLLTQIDDYNYGARAYSIRTLAAIADP-   92 (208)
T ss_dssp             GGHHHHHHHTT-SCCHHHHHHHHHHHHHHGG-----------------GGHHHHHHCCCTTCHHHHHHHHHHHHHHCCG-
T ss_pred             hhHHHHHHHhC-CCCHHHHHHHHHHHHHhCc-----------------chHHHHHHHhhCCCHHHHHHHHHHHHHhcCc-
Confidence            45666777776 3566677777776655432                 1334455666667778888888888776522 


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLA-KQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~-~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                              ..++.+...+...     .++.++..++.+|..+........ ........++.+..++.+. ++.++..++
T Consensus        93 --------~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  158 (208)
T 5N3U_B           93 --------RALDVLIDAAATD-----FAPSVRRAAAKGLGNLHWHKLEFPDNQTAPKKALETLLFISQDA-EWSIRYAAI  158 (208)
T ss_dssp             --------GGHHHHHHHHHHC-----CCHHHHHHHHHHHTTSCGGGSCTTHHHHHHHHHHHHHHHHTTCS-SHHHHHHHH
T ss_pred             --------chHHHHHHHHccC-----CCHHHHHHHHHHHHhhhccCCCCCCCccCChHHHHHHHHHhcCC-CHHHHHHHH
Confidence                    2344555555431     256788888888888864221111 1111123566666777665 677888888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       159 ~~l~~~~~~  167 (208)
T 5N3U_B          159 VGLQGLVNI  167 (208)
T ss_dssp             HHHHHGGGC
T ss_pred             HHHHHHcCC
Confidence            888887764


No 361
>6QH5_B AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=84.43  E-value=0.06  Score=53.82  Aligned_cols=145  Identities=12%  Similarity=0.031  Sum_probs=94.1  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..+....+.        ......+++.+...+.+.++.++..++.+|..+.....
T Consensus       122 ~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~--------~~~~~~~~~~l~~~l~d~~~~vr~~a~~~l~~~~~~~~  192 (592)
T 6QH5_B          122 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------MVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHP  192 (592)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCch--------hhcCccHHHHHHHHhCCCCHHHHHHHHHHHHHHHhcCC
Confidence            4566667776 46788889999999988764221        11224677788888888888899999999998886521


Q NP_000290.2     628 --LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 --~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                        ........+++.+...+.+      .++.++..++.+|..+....+..     ....++.+...+.+. ++.++..++
T Consensus       193 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~~~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  260 (592)
T 6QH5_B          193 NSNLLDLNPQNINKLLTALNE------CTEWGQIFILDCLSNYNPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  260 (592)
T ss_pred             hhhhHhHHhhHHHHHHHHhcC------CCHHHHHHHHHHHHHHhcCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence              1111122355566666654      25677778888888877542221     112455555666655 677888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       261 ~~l~~l~~  268 (592)
T 6QH5_B          261 KVLMKFLE  268 (592)
T ss_pred             HHHHHHHh
Confidence            88877763


No 362
>2DB0_A 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=84.35  E-value=0.062  Score=47.21  Aligned_cols=104  Identities=10%  Similarity=0.179  Sum_probs=59.0  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|+..+. +.++.++..++.+|..+......        .  ...+++.+...+.+. ++.++..++.+|..+...
T Consensus        32 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~~~~~  100 (253)
T 2DB0_A           32 SVLKKLIELLD-DDLWTVVKNAISIIMVIAKTRED--------L--YEPMLKKLFSLLKKSEAIPLTQEIAKAFGQMAKE  100 (253)
T ss_dssp             HHHHHHHHHTT-CSCHHHHHHHHHHHHHHHTTCGG--------G--HHHHHHHHHHHHHHCCSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHhhCHH--------H--HHHHHHHHHHHHhcCCChhHHHHHHHHHHHHHHh
Confidence            45666777776 46677888888888777643110        0  122445566666666 677888888888777643


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ...  .+ ...++.+...+.+      .++.++..++.++..+..
T Consensus       101 ~~~--~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~  136 (253)
T 2DB0_A          101 KPE--LV-KSMIPVLFANYRI------GDEKTKINVSYALEEIAK  136 (253)
T ss_dssp             CHH--HH-HHHHHHHHHHSCC------CSHHHHHHHHHHHHHHHH
T ss_pred             CHH--HH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            110  00 1133444444444      245556666666665544


No 363
>2DB0_B 253aa long hypothetical protein; HEAT repeats, helical structure, Structural; 2.2A {Pyrococcus horikoshii}
Probab=84.35  E-value=0.062  Score=47.21  Aligned_cols=104  Identities=10%  Similarity=0.179  Sum_probs=59.0  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.|+..+. +.++.++..++.+|..+......        .  ...+++.+...+.+. ++.++..++.+|..+...
T Consensus        32 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~~~~~  100 (253)
T 2DB0_B           32 SVLKKLIELLD-DDLWTVVKNAISIIMVIAKTRED--------L--YEPMLKKLFSLLKKSEAIPLTQEIAKAFGQMAKE  100 (253)
T ss_dssp             HHHHHHHHHTT-CSSHHHHHHHHHHHHHHGGGCGG--------G--HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHhhCHH--------H--HHHHHHHHHHHHhcCCChhHHHHHHHHHHHHHHh
Confidence            45666777776 46677888888888777643110        0  122445566666666 677888888888777643


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ...  .+ ...++.+...+.+      .++.++..++.++..+..
T Consensus       101 ~~~--~~-~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~  136 (253)
T 2DB0_B          101 KPE--LV-KSMIPVLFANYRI------GDEKTKINVSYALEEIAK  136 (253)
T ss_dssp             CHH--HH-HHHHHHHTTTCCC------CSHHHHHHHHHHHHHHHH
T ss_pred             CHH--HH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            110  00 1133444444444      245556666666665544


No 364
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=84.21  E-value=0.064  Score=54.84  Aligned_cols=140  Identities=15%  Similarity=0.148  Sum_probs=93.7  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. ++++.++..++.++..+......        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        75 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  143 (623)
T 2JKT_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (623)
T ss_dssp             CHHHHHHHTT-CSCHHHHHHHHHHHHHSCCCCHH--------H--HHHHHHHHHHHHHTTCHHHHHHHHHHHHHHCCHHH
T ss_pred             HHHHHHHHHc-CCCccHHHHHHHHHHHhcCCCHH--------H--HHHHHHHHHHHHhCCCHHHHHHHHHHHHhhCCHHH
Confidence            4566777777 46778888888888887653221        1  12355667777777788899999999988764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+...+  .+      .++.++..++.+|..+....+..   +.....++.+..++.+. ++.++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vr~~a~~~L~~~~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  208 (623)
T 2JKT_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (623)
T ss_dssp             -----HHHHTTHHHHHHHCTT------SCHHHHHHHHHHHHHHHHHCTTT---CCCCTHHHHHHGGGGCS-SHHHHHHHH
T ss_pred             -----HHHHHHhHHHHHHcCC------CCHHHHHHHHHHHHHHHHHChhh---cCccchHHHHHHHhcCC-CHHHHHHHH
Confidence                 112445556666  44      36788999999999887642221   11234567777777766 778888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~l~~l~~  216 (623)
T 2JKT_A          209 SLITTLAQ  216 (623)
T ss_dssp             HHHHHHHT
T ss_pred             HHHHHHHH
Confidence            88888775


No 365
>3LTJ_A AlphaRep-4; protein engineering, HEAT-like repeat, PROTEIN; 1.8A {synthetic}
Probab=84.11  E-value=0.065  Score=45.71  Aligned_cols=28  Identities=11%  Similarity=0.126  Sum_probs=18.0  Template_Neff=12.300

Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++.+...+.+. +..++..++.++..+..
T Consensus       140 ~~~l~~~l~~~-~~~v~~~a~~~l~~~~~  167 (201)
T 3LTJ_A          140 VEPLIKALKDE-DGWVRQSAADALGEIGG  167 (201)
T ss_dssp             HHHHHHHTTCS-SHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHHhCC-ChHHHHHHHHHHHHhCc
Confidence            44455555544 56777778888777664


No 366
>4P6Z_B BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=84.10  E-value=0.065  Score=53.98  Aligned_cols=145  Identities=12%  Similarity=0.047  Sum_probs=94.3  Template_Neff=12.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..+....+.        .+....+++.+...+.+.++.++..++.+|..+.... 
T Consensus       138 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  208 (600)
T 4P6Z_B          138 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------LVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHP  208 (600)
T ss_pred             HHHHHHHhcC-CCCHHHHHHHHHHHHHHHhhChH--------HhhccChHHHHHHHhcCCCHHHHHHHHHHHHHHHhhCC
Confidence            4566677776 46778888999999988764321        1112457778888888888899999999999888652 


Q NP_000290.2     627 L-LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e-~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      . ........+++.+...+.+      .+..++..++.+|..+....+..     ....++.+...+.+. +..++..++
T Consensus       209 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~~~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  276 (600)
T 4P6Z_B          209 SSNLLDLNPQSINKLLTALNE------CTEWGQIFILDCLANYMPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  276 (600)
T ss_pred             CcchhccCHHHHHHHHHHhhc------CCHHHHHHHHHHHHHhCCCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            1 1111122355556666654      25677778888888876542221     123455566666655 677788888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       277 ~~l~~l~~  284 (600)
T 4P6Z_B          277 KVLMKFME  284 (600)
T ss_pred             HHHHHHHH
Confidence            88777764


No 367
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=84.02  E-value=0.067  Score=54.81  Aligned_cols=140  Identities=15%  Similarity=0.148  Sum_probs=93.1  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++.++. ++++.++..++.++..+......        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        75 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  143 (621)
T 6QH7_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (621)
T ss_dssp             CHHHHHHHTT-CSSHHHHHHHHHHHHHSCCCCHH--------H--HHHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHHH
T ss_pred             HHHHHHHHHc-CCCccHHHHHHHHHHHHcCCCHH--------H--HHHHHHHHHHHHhcCCHHHHHHHHHHHHhhCCHHH
Confidence            4556667776 46777888888888887754221        1  12345666677777788899999999988764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+...+  .+      .++.++..++.+|..+....+..   +.....++.+..++.+. ++.++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vr~~a~~~L~~~~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  208 (621)
T 6QH7_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (621)
T ss_dssp             -----HHHHTTHHHHHHTTSC------CCHHHHHHHHHHHHHHHHHCGGG---CCCCTTHHHHHHGGGCS-SHHHHHHHH
T ss_pred             -----HHHHHhhHHHHHHcCC------CCHHHHHHHHHHHHHHHHHChhh---cCccchHHHHHHHhcCC-CHHHHHHHH
Confidence                 112445556666  44      36788999999999887643221   11234567777777765 778888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~l~~l~~  216 (621)
T 6QH7_A          209 SLITTLAQ  216 (621)
T ss_dssp             HHHHHHHT
T ss_pred             HHHHHHHH
Confidence            88888775


No 368
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=83.93  E-value=0.067  Score=53.93  Aligned_cols=67  Identities=18%  Similarity=0.165  Sum_probs=49.2  Template_Neff=12.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.+...+. +.++.++..++.+|..+....+.        .  ...+++.|...+.+.++.++..++.+|..+...
T Consensus       135 ~~~~l~~~l~-~~~~~vr~~a~~~L~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  201 (585)
T 6CRI_R          135 LAGEVEKLLK-TSNSYLRKKAALCAVHVIRKVPE--------L--MEMFLPATKNLLNEKNHGVLHTSVVLLTEMCER  201 (585)
T ss_pred             HHHHHHHHHh-CCChHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHh
Confidence            4566777777 46778888999999888764221        1  135677788888878888999999999888754


No 369
>4UQI_B AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ENDOCYTOSIS, PROTEIN TRANSPORT, LIPID BINDING; HET: IHP; 2.79A {RATTUS NORVEGICUS}
Probab=83.87  E-value=0.069  Score=55.16  Aligned_cols=145  Identities=12%  Similarity=0.031  Sum_probs=94.3  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..+....+.        .+....+++.+..++.+.++.++..++.+|..+.....
T Consensus       122 l~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  192 (657)
T 4UQI_B          122 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------MVEDQGFLDSLRDLIADSNPMVVANAVAALSEISESHP  192 (657)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCHH--------HhcCcchHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCC
Confidence            4566667776 46778888999999988764321        11224677788888888888899999999999887521


Q NP_000290.2     628 --LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 --~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                        ........+++.+...+.+      .++.++..++.+|..+.......     ...+++.+...+.+. +..++..++
T Consensus       193 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~L~~l~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  260 (657)
T 4UQI_B          193 NSNLLDLNPQNINKLLTALNE------CTEWGQIFILDCLSNYNPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  260 (657)
T ss_pred             hhhhhhhhhcHHHHHHHHhcC------CCHHHHHHHHHHHHhhCCCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence              1111123355666666655      35677888888888887542221     112455566666555 667777777


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       261 ~~l~~l~~  268 (657)
T 4UQI_B          261 KVLMKFLE  268 (657)
T ss_pred             HHHHHHHh
Confidence            77777663


No 370
>5XAH_A Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=83.55  E-value=0.071  Score=50.49  Aligned_cols=142  Identities=14%  Similarity=0.108  Sum_probs=83.6  Template_Neff=12.900

Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHP-LLHRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~-e~~~ll~~giI~  638 (747)
                      ++.++..++.++..++.....   . ....+ -..+++.+...+.+. +..++..++.++..++... .........+++
T Consensus       163 ~~~v~~~a~~~l~~l~~~~~~---~-~~~~~-~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~  237 (416)
T 5XAH_A          163 DAMLLEHAGEAIPALAAAAGG---D-SFAPF-FAGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLP  237 (416)
T ss_dssp             HHHHHHHHHHHHHHHHHHHTS---T-TTHHH-HHHHHHHHHHTTSSSSCHHHHHHHHHHHHHHHHHHGGGGGGGHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHhCc---c-chHHH-HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHH
Confidence            455667778888777654210   0 01111 133556666666543 3567778888888877541 111111123566


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-SSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+.+      .++.++..++.+|..++...+......+ ..+++.+...+. +. ++.++..++.++..++...
T Consensus       238 ~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~-~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_A          238 VLLSTAQE------ADPEVRSNAIFGMGVLAEHGGHPAQEHF-PKLLGLLFPLLARER-HDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHTSC------SSHHHHHHHHHHHHHHHHHHHHHHHTTH-HHHHHHHTTHHHHCC-CHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHhhc------CCHHHHHHHHHHHHHHHHhcCchHHhhH-HHHHHHHHHHhccCC-CHHHHHHHHHHHHHHHHhC
Confidence            66666655      3678889999999998865332222222 235666777776 44 6778888888888877543


No 371
>5XAH_C Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=83.55  E-value=0.071  Score=50.49  Aligned_cols=142  Identities=14%  Similarity=0.108  Sum_probs=83.6  Template_Neff=12.900

Q NP_000290.2     561 KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG-NSDVVRSGASLLSNMSRHP-LLHRVMGNQVFP  638 (747)
Q Consensus       561 d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~-d~eVr~~AL~aLsnLa~~~-e~~~ll~~giI~  638 (747)
                      ++.++..++.++..++.....   . ....+ -..+++.+...+.+. +..++..++.++..++... .........+++
T Consensus       163 ~~~v~~~a~~~l~~l~~~~~~---~-~~~~~-~~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~  237 (416)
T 5XAH_C          163 DAMLLEHAGEAIPALAAAAGG---D-SFAPF-FAGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLP  237 (416)
T ss_dssp             HHHHHHHHHTHHHHHHHHHTS---T-TTHHH-HHHHHHHHHHTTSTTSCHHHHHHHHHHHHHHHHHHGGGGGGGHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHhCc---c-chHHH-HHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHH
Confidence            455667778888777654210   0 01111 133556666666543 3567778888888877541 111111123566


Q NP_000290.2     639 EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-SSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       639 ~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .+...+.+      .++.++..++.+|..++...+......+ ..+++.+...+. +. ++.++..++.++..++...
T Consensus       238 ~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~-~~i~~~l~~~l~~~~-~~~v~~~a~~~l~~l~~~~  307 (416)
T 5XAH_C          238 VLLSTAQE------ADPEVRSNAIFGMGVLAEHGGHPAQEHF-PKLLGLLFPLLARER-HDRVRDNICGALARLLMAS  307 (416)
T ss_dssp             HHHHHTTC------SSHHHHHHHHHHHHHHHHHSHHHHHTTH-HHHHHHHTHHHHHCC-CHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHhhc------CCHHHHHHHHHHHHHHHHhcCchHHhhH-HHHHHHHHHHhccCC-CHHHHHHHHHHHHHHHHhC
Confidence            66666655      3678889999999998865332222222 235666777776 44 6778888888888877543


No 372
>5FRS_A SISTER CHROMATID COHESION PROTEIN PDS5; COHESIN, DNA REPLICATION, SISTER CHROMATID; 4.073A {SACCHAROMYCES CEREVISIAE}
Probab=83.54  E-value=0.08  Score=57.55  Aligned_cols=149  Identities=7%  Similarity=0.080  Sum_probs=99.5  Template_Neff=9.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.|...+. +.++.++..|+.+|..+....+.   . .... ....+++.++..+.+.++.++..++.++..+... +
T Consensus       282 vl~~L~~~l~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~d~~~~vR~~a~~~l~~~~~~~~  355 (703)
T 5FRS_A          282 VIGFIYHELS-SENELFRKEATKLIGQILTSYSD---L-NFVS-THSDTFKAWISKIADISPDVRVEWTESIPQIIATRE  355 (703)
T ss_pred             hHHHHHHHhc-CCCHHHHHHHHHHHHHHhCCCCc---c-cHHH-HchhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHhCH
Confidence            5666666676 46778899999999988764221   0 0011 1245667777777778889999999999988764 2


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..|+.+|+.+.....  .........++.+...+.+. +..++..|+.
T Consensus       356 ~~----~~~i~~~l~~~l~D------~d~~VR~~A~~~L~~~~~~~~--~~~~~~~~~l~~l~~~l~d~-~~~VR~~A~~  422 (703)
T 5FRS_A          356 DI----SKELNQALAKTFID------SDPRVRRTSVMIFNKVPVTEI--WKNITNKAIYTSLLHLAREK-HKEVRELCIN  422 (703)
T ss_pred             HH----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHhhcccCc--cccCCCcccHHHHHHHhcCC-CHHHHHHHHH
Confidence            11    22356666666666      478999999999998865321  00111234567777777766 7789999999


Q NP_000290.2     707 LLSDMWSSK  715 (747)
Q Consensus       707 aLsnL~~~~  715 (747)
                      +|..+....
T Consensus       423 ~L~~l~~~~  431 (703)
T 5FRS_A          423 TMAKFYSNS  431 (703)
T ss_pred             HHHHHHHhC
Confidence            888777543


No 373
>4HM9_A Beta-catenin-like protein 1; all alpha-helical, armadillo repeats, PROTEIN; 3.1001A {Homo sapiens}
Probab=83.50  E-value=0.087  Score=56.79  Aligned_cols=136  Identities=13%  Similarity=0.067  Sum_probs=87.4  Template_Neff=8.100

Q NP_000290.2     246 TIPKAVQYLSS------QDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSP--NQNVQQAAAGALRNLVFR  317 (747)
Q Consensus       246 iL~~Ll~lL~s------sd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~--d~eVr~~AL~aLs~La~~  317 (747)
                      +++.|+..+..      .+...+..++.+|.+++...+.....+...++++.|+.++...  ....+..+..+|..++..
T Consensus       198 ~l~~Lv~~L~~l~e~~~~d~~~~~~al~iL~nL~~~~~~~~~~i~~~g~l~~Ll~lL~~~~~~~~~k~~AaeiL~~L~~~  277 (568)
T 4HM9_A          198 VVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQD  277 (568)
T ss_dssp             HHHHHHHHHTTCCTTSHHHHHHHHHHHHHHHHHHHHCGGGHHHHCCCCCHHHHHHHHHSSCCCCHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHHhcccccccchHHHHHHHHHHHHHHhccCHHHHHHHHHCCHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcC
Confidence            44555555554      4556778888999988865433333344456788888888764  466788889999988865


Q NP_000290.2     318 STTNKLETRRQNGIREAVSLLRR-----TG---NAEIQKQLTGLLWNLSSTDELKEELIA-DALPVLADRVII  381 (747)
Q Consensus       318 ~~~~~~~ll~~~IL~~Ll~lL~s-----s~---d~eVr~~AL~aLsnLas~~~~~~~Lve-giLe~Lv~LL~~  381 (747)
                      .......+...+.++.|+.++..     ..   .......++.+|..++........++. ++++.|+.+|+.
T Consensus       278 ~~~~r~~l~~~g~I~~LL~lL~~y~~~d~~~~~e~e~~en~~~aL~~L~~~~~~r~~f~~~~gv~lLv~lL~~  350 (568)
T 4HM9_A          278 NDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLRE  350 (568)
T ss_dssp             CHHHHHHHHHTTHHHHHHHHHGGGTTSCCSSSHHHHHHHHHHHHHHHHTTSTHHHHHHHHTTHHHHHHHHHHH
T ss_pred             CHHHHHHHHhCchHHHHHHHHHhhhccCCCCHHHHHHHHHHHHHHHHHhCCHHHHHHHHHCChHHHHHHHHhC
Confidence            44444444445677777777731     11   123444557788887766555555555 778888888875


No 374
>5FRP_A SISTER CHROMATID COHESION PROTEIN PDS5; CELL CYCLE, CELL DIVISION, COHESIN; 2.895A {SACCHAROMYCES CEREVISIAE}
Probab=83.43  E-value=0.082  Score=57.48  Aligned_cols=149  Identities=7%  Similarity=0.080  Sum_probs=99.6  Template_Neff=9.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.|...+. +.++.++..|+.+|..+....+.   . .... ....+++.++..+.+.++.++..++.++..+... +
T Consensus       282 vl~~L~~~l~-~~~~~vR~~A~~~L~~l~~~~~~---~-~~~~-~~~~~~~~l~~~l~d~~~~vR~~a~~~l~~~~~~~~  355 (703)
T 5FRP_A          282 VIGFIYHELS-SENELFRKEATKLIGQILTSYSD---L-NFVS-THSDTFKAWISKIADISPDVRVEWTESIPQIIATRE  355 (703)
T ss_dssp             THHHHHHHHT-CSSHHHHHHHHHHHHHHTTSCCS---S-CHHH-HTHHHHHHHHGGGGCSSHHHHHHHHHTHHHHHHHCC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCCC---c-CHHH-HCHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCH
Confidence            5666666676 46778899999999988764221   0 0011 1245667777777778889999999999988764 2


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..    ...+++.+...+.+      .++.++..|+.+|+.+.....  .........++.+...+.+. +..++..|+.
T Consensus       356 ~~----~~~i~~~l~~~l~D------~d~~VR~~A~~~L~~~~~~~~--~~~~~~~~~l~~l~~~l~d~-~~~VR~~A~~  422 (703)
T 5FRP_A          356 DI----SKELNQALAKTFID------SDPRVRRTSVMIFNKVPVTEI--WKNITNKAIYTSLLHLAREK-HKEVRELCIN  422 (703)
T ss_dssp             SC----SSHHHHHHHHHTTC------SSHHHHHHHHHHHHHSCHHHH--HHHCCCHHHHHHHHHGGGBS-CHHHHHHHHH
T ss_pred             HH----HHHHHHHHHHHhcC------CCHHHHHHHHHHHhhcChhHH--hhcCCchHHHHHHHHHHhcC-CHHHHHHHHH
Confidence            11    22356666677666      478999999999998865311  00111234567777777766 7789999999


Q NP_000290.2     707 LLSDMWSSK  715 (747)
Q Consensus       707 aLsnL~~~~  715 (747)
                      +|..+....
T Consensus       423 ~L~~l~~~~  431 (703)
T 5FRP_A          423 TMAKFYSNS  431 (703)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            888777543


No 375
>5GM6_G Prp8, Brr2, Snu114, Rse1, Cus1; spliceosome, RNA splicing, Bact, Catalytically; HET: GTP, ADP, ZN; 3.5A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=83.42  E-value=0.077  Score=58.66  Aligned_cols=69  Identities=9%  Similarity=-0.111  Sum_probs=31.7  Template_Neff=11.400

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      +.+...+.+.++.++..++.++..+...............+++.+...+.+.+..++..++.++..++.
T Consensus       603 ~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~v~~~a~~~l~~l~~  671 (971)
T 5GM6_G          603 STILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITS  671 (971)
T ss_pred             HHHHHHhcCCCHHHHHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHh
Confidence            333344444455566666665555543211111100111234444444444445566666666666554


No 376
>5ZWM_1 Pre-mRNA-splicing factor 8, U4/U6 small; spliceosome, assembly, pre-B complex, U1; HET: GTP; 3.4A {Saccharomyces cerevisiae S288c}
Probab=83.42  E-value=0.077  Score=58.66  Aligned_cols=69  Identities=9%  Similarity=-0.111  Sum_probs=31.7  Template_Neff=11.400

Q NP_000290.2     248 PKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVF  316 (747)
Q Consensus       248 ~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~  316 (747)
                      +.+...+.+.++.++..++.++..+...............+++.+...+.+.+..++..++.++..++.
T Consensus       603 ~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~v~~~a~~~l~~l~~  671 (971)
T 5ZWM_1          603 STILNHLKHKTPLVRQHAADLCAILIPVIKNCHEFEMLNKLNIILYESLGEVYPEVLGSIINAMYCITS  671 (971)
T ss_dssp             HHHHHHTTCSSHHHHHHHHHHHHHHHHHHHHTTCHHHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHhcCCCHHHHHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHh
Confidence            333344444455566666665555543211111100111234444444444445566666666666554


No 377
>3TJZ_B ADP-ribosylation factor 1, Coatomer subunit; protein trafficking, Golgi membrane, protein; HET: GNP; 2.9A {Saccharomyces cerevisiae}
Probab=83.38  E-value=0.075  Score=50.15  Aligned_cols=102  Identities=16%  Similarity=0.082  Sum_probs=56.5  Template_Neff=12.100

Q NP_000290.2     596 GLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       596 iI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~  675 (747)
                      .++.+..++.+.+..++..++.+|..+......   ....+++.+..++.+      .++.++..++.+|..+....+..
T Consensus       251 ~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~---~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~  321 (355)
T 3TJZ_B          251 LFDFIESCLRNKHEMVVYEAASAIVNLPGCSAK---ELAPAVSVLQLFCSS------PKAALRYAAVRTLNKVAMKHPSA  321 (355)
T ss_pred             HHHHHHHHhCCCCHHHHHHHHHHHHHHccCCHH---HHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHcCHHH
Confidence            445555556555666666666666666543100   001233444444444      25667777778877776532211


Q NP_000290.2     676 AKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       676 ~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                      .     ...++.+..++.+. +..++..|+.+|..+.
T Consensus       322 ~-----~~~~~~l~~~l~~~-~~~vr~~a~~~L~~l~  352 (355)
T 3TJZ_B          322 V-----TACNLDLENLVTDA-NRSIATLAITTLLKTG  352 (355)
T ss_pred             H-----HHHHHHHHHHhcCC-CHHHHHHHHHHHHHhh
Confidence            1     12335566666655 6677888888777764


No 378
>6CRI_R Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=83.30  E-value=0.075  Score=53.54  Aligned_cols=101  Identities=12%  Similarity=0.040  Sum_probs=51.9  Template_Neff=12.500

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.++.++..++..+..+....       ....+++.+...+.+.++.++..++.++..+....+...   
T Consensus       100 ~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~~~~~~~~~~---  169 (585)
T 6CRI_R          100 MTNCIKNDLNHSTQFVQGLALCTLGCMGSSE-------MCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELM---  169 (585)
T ss_pred             HHHHHHHHhcCCCHHHHHHHHHHHHhhCCHH-------HHHHHHHHHHHHHhCCChHHHHHHHHHHHHHHHHCHHHH---
Confidence            4444444555555566666666665554211       011234445555555556666666666666654322111   


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ..+++.+...+. +.++.++..++.++..+..
T Consensus       170 --~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~  200 (585)
T 6CRI_R          170 --EMFLPATKNLLN-EKNHGVLHTSVVLLTEMCE  200 (585)
T ss_pred             --HHHHHHHHHHHc-CCCHHHHHHHHHHHHHHHH
Confidence              234445555554 4455666666666666654


No 379
>6U62_A Regulatory-associated protein of mTOR, Ras-related; signaling complex, GTPase, lysosome, SIGNALING; HET: GDP, GTP;{Homo sapiens}
Probab=83.02  E-value=0.095  Score=62.46  Aligned_cols=159  Identities=10%  Similarity=0.013  Sum_probs=98.7  Template_Neff=8.000

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSN  621 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsn  621 (747)
                      ...|+++.++++|++ ...+.+...+.+...++.-+..     ....+++.+....++.+|....  +..+..++.+|+.
T Consensus       468 l~~gifp~~~~ll~~-~~~~~~~~l~~iw~kil~~d~~-----~~~~l~~~~~~~~f~~~l~~~~~~~~~~~~~afiLa~  541 (1392)
T 6U62_A          468 LSVGIFPYVLKLLQS-SARELRPLLVFIWAKILAVDSS-----CQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILAV  541 (1392)
T ss_dssp             HHHTCHHHHHHGGGC-CCSTTHHHHHHHHHHHHTTCGG-----GHHHHHHTTTHHHHHHHHHSTTSCSSSHHHHHHHHHH
T ss_pred             HHcCcHHHHHHHHHc-cchhhHHHHHHHHHHHHhhCch-----hHHHHHhccchHHHHHhhcCCCCChhHHHHHHHHHHH
Confidence            466778888888873 4445554445555555443221     1222234444555666665432  2244566667777


Q NP_000290.2     622 MSRH-PLLH-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       622 La~~-~e~~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ++.. .... .....+++..+...|..      .++.++..++-+|+.|....+..+...+..+....|..++.+. .++
T Consensus       542 ~~~~~~~~q~~~~~~~~~~~~~~~l~~------~~~~~r~W~~l~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~d~-~pe  614 (1392)
T 6U62_A          542 IVNSYHTGQEACLQGNLIAICLEQLND------PHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDP-IPE  614 (1392)
T ss_dssp             HSTTCHHHHHHHHHTTHHHHHHTSTTC------SCHHHHHHHHHHHHHHSSSCHHHHHHHHTTTHHHHSGGGGGCS-STT
T ss_pred             HHhhCcchHHHHHhchHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHHHHhhcccHHHHHHHHhcCC-CHH
Confidence            7754 2222 22233455666666654      3688899999999999876555555555555667788888877 899


Q NP_000290.2     700 AAEAARLLLSDMWSSK  715 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~~  715 (747)
                      ||.+|+.+|+.++...
T Consensus       615 VRaaav~aL~~~i~~~  630 (1392)
T 6U62_A          615 VRCAAVFALGTFVGNS  630 (1392)
T ss_dssp             HHHHHHHHHHHHSCCT
T ss_pred             HHHHHHHHHHHhhCCC
Confidence            9999999998887553


No 380
>6BCX_W mTOR, Target of rapamycin complex; PIKK, TRANSFERASE; HET: ATP; 3.0A {Homo sapiens}
Probab=82.82  E-value=0.098  Score=62.11  Aligned_cols=159  Identities=10%  Similarity=0.013  Sum_probs=98.0  Template_Neff=7.900

Q NP_000290.2     544 YHSDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSN  621 (747)
Q Consensus       544 ve~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsn  621 (747)
                      ...|+++.++++|++ ...+.+...+.+...++.-+..     ....+++.+....++.+|....  +..+..++.+|+.
T Consensus       476 l~~gifp~~~~ll~~-~~~~~~~~l~~iw~kil~~d~~-----~~~~l~~~~~~~~f~~~l~~~~~~~~~~~~~a~iLa~  549 (1343)
T 6BCX_W          476 LSVGIFPYVLKLLQS-SARELRPLLVFIWAKILAVDSS-----CQADLVKDNGHKYFLSVLADPYMPAEHRTMTAFILAV  549 (1343)
T ss_dssp             HHHTCHHHHHHGGGC-CCGGGHHHHHHHHHHHHHHCGG-----GHHHHHHTTHHHHHHHHHTCTTSCHHHHHHHHHHHHH
T ss_pred             HHcCcHHHHHHHHHc-cchhhHHHHHHHHHHHHhhCcc-----hHHHHHhccchhHHHHhhcCCCCChhHHHHHHHHHHH
Confidence            356778888888873 4444544444455555443221     1222234444555666665432  2234566667777


Q NP_000290.2     622 MSRH-PLLH-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       622 La~~-~e~~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ++.. .... .....+++..+...|..      .++.++..++-+|+.|....+..+...+..+....+..++.+. .++
T Consensus       550 ~~~~~~~~q~~~~~~~~~~~~~~~l~~------~~~~~r~W~~l~l~~l~~~~~~~~~~~~~~~~~~~~~~~l~d~-~pe  622 (1343)
T 6BCX_W          550 IVNSYHTGQEACLQGNLIAICLEQLND------PHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDP-IPE  622 (1343)
T ss_dssp             HSTTCHHHHHHHHHTTHHHHHHHTTTC------SCHHHHHHHHHHHHHHTTTCHHHHHHHHHHTHHHHHGGGGGCS-SHH
T ss_pred             HHhhCchhHHHHHhchHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHHHHhhcccHHHHHHHHhcCC-CHH
Confidence            7654 2222 22333456666666654      3688899999999999876555555555555667788888877 899


Q NP_000290.2     700 AAEAARLLLSDMWSSK  715 (747)
Q Consensus       700 Vr~aAL~aLsnL~~~~  715 (747)
                      ||.+++.+|+.++...
T Consensus       623 vRaa~v~aL~~~i~~~  638 (1343)
T 6BCX_W          623 VRCAAVFALGTFVGNS  638 (1343)
T ss_dssp             HHHHHHHHHHHHHTTC
T ss_pred             HHHHHHHHHHHhhCCC
Confidence            9999999998887653


No 381
>4QMH_A LP04448p; PROTEIN BINDING, TOG DOMAIN; 1.652A {Drosophila melanogaster}
Probab=82.76  E-value=0.081  Score=45.96  Aligned_cols=114  Identities=8%  Similarity=0.065  Sum_probs=67.9  Template_Neff=12.700

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      .+++.+...+.+.++.++..++.+|..+.............+++.+...+.+      .++.++..++.++..++.....
T Consensus        17 ~l~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~~~~~~l~~~l~d------~~~~v~~~a~~~l~~l~~~~~~   90 (241)
T 4QMH_A           17 QITEALLKEMSDKDWKTRNEGLTKLQAIISEARLIKPSIGDLAPALAHRLVD------SNAKIAQTTLAICEQLATAMGA   90 (241)
T ss_dssp             GSCHHHHHHHTCSSHHHHHHHHHHHHHHHHHHCSBCSCCTTHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHGG
T ss_pred             HhhHHHHHhcCCccHHHHHHHHHHHHHHHHhCCcCcccHHHHHHHHHHHHcC------CCHHHHHHHHHHHHHHHHHhcH
Confidence            3455566666677778888888888888764211110112345555666655      3678888888888888764322


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      ...... ..+++.+...+.+. +..++..++.+|..+.....
T Consensus        91 ~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~~~  130 (241)
T 4QMH_A           91 GCRNHV-RNLFPGFLHALGDN-KSFVRAAALNCINSFGEKGG  130 (241)
T ss_dssp             GGGGGH-HHHHHHHHHHTTCS-SHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHH-HHHHHHHHHHhcCC-cHHHHHHHHHHHHHHHHhcC
Confidence            111111 23455666666554 55677777777777665443


No 382
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=82.76  E-value=0.083  Score=54.05  Aligned_cols=140  Identities=15%  Similarity=0.148  Sum_probs=92.9  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.++..+. +.+..++..++.++..+......        .  ...+++.+...+.+.++.++..++.+|..+.....
T Consensus        75 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~~  143 (621)
T 6QH5_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE--------L--IRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (621)
T ss_pred             hHHHHHHHhc-CCCHHHHHHHHHHHHHHhhcCHH--------H--HHHHHHHHHHHhcCCCHHHHHHHHHHHHHhcCHHH
Confidence            4556667776 46677888888888887653221        1  12355666777777788899999999888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+...+  .+      .++.++..++.+|..+....+..   +.....++.+..++.+. ++.++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vr~~a~~~L~~l~~~~~~~---~~~~~~~~~l~~~l~~~-~~~vr~~a~  208 (621)
T 6QH5_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDL---VPMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (621)
T ss_pred             -----HHHHHHHHHHHhcCCC------CCHHHHHHHHHHHHHHHHhChHH---ccHHHHHHHHHHHhcCC-CHHHHHHHH
Confidence                 112445555666  44      36788999999999887642221   11234567777777766 778888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~L~~l~~  216 (621)
T 6QH5_A          209 SLITTLAQ  216 (621)
T ss_pred             HHHHHHHH
Confidence            88888775


No 383
>6EMK_C Serine/threonine-protein kinase TOR2 (E.C.2.7.1.67,2.7.11.1), Target; target of rapamycin, torc2, FRB; 8.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=82.75  E-value=0.086  Score=64.86  Aligned_cols=71  Identities=13%  Similarity=0.124  Sum_probs=44.6  Template_Neff=11.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLE-ACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~-~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.|+..+. +.+..++. .++.+|..++.....     ....+ -..+++.+...+.+.+..++..++.+|..++..
T Consensus       922 ~~~~L~~~l~-d~~~~v~~~~a~~~L~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~~~~~L~~l~~~  993 (2474)
T 6EMK_C          922 VIHNLMKILN-DPSLSIHHTAAIQAIMHIFQNLGL-----RCVSF-LDQIIPGIILVMRSCPPSQLDFYFQQLGSLISI  993 (2474)
T ss_dssp             TTCCCCCCTT-CCCCCCCCCCCTTTCCCCCCCCCC-----CCCCC-SSTTCCCCCCCCCCCCHHHHCCCCCCTTTCCCC
T ss_pred             HHHHHHHHHc-CCchHHHHHHHHHHHHHHHHHcch-----hhHHh-HhhHHHHHHHHHhhCCHHHHHHHHHHHHHHHHH
Confidence            4566667776 34555555 778888887764221     01111 134566677777666677888888888888764


No 384
>5MU7_A Coatomer subunit beta, Coatomer subunit; coatomer, COPI, beta COP, delta; 2.57A {Chaetomium thermophilum var. thermophilum DSM 1495}
Probab=82.68  E-value=0.082  Score=49.28  Aligned_cols=71  Identities=11%  Similarity=-0.055  Sum_probs=38.3  Template_Neff=12.800

Q NP_000290.2     548 AIRTYLNLM-GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       548 ~I~~LL~LL-~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      .++.++..+ . ++++.++..++.+|..+......   . .... .....++.+...+.+.++.++..++.+|..+..
T Consensus        39 ~~~~l~~~l~~-~~~~~~r~~a~~~l~~~~~~~~~---~-~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~  110 (373)
T 5MU7_A           39 LLMHIIRFVMP-SKSKPLKKLLYFYYEICPKLDSQ---G-KLKQ-EFILVCNGIRNDLQHPNEYIRGNTLRFLCKLRE  110 (373)
T ss_dssp             GHHHHHHHTTT-CCCHHHHHHHHHHHHHSCCBCTT---S-CBCT-HHHHHHHHHHHHTTCSSHHHHHHHHHHHTTCCC
T ss_pred             HHHHHHHHHcC-CCChhhHHHHHHHHHhccccCCc---c-hHHH-HHHHHHHHHHHHccCCCHHHHHHHHHHHHhccC
Confidence            345555553 4 35666777777777776542111   0 0000 012345556666666666777777777766543


No 385
>6CRI_I Bone marrow stromal antigen 2,Nef; AP, HIV, Nef, trafficking, VIRAL; HET: GTP;{Homo sapiens}
Probab=82.65  E-value=0.081  Score=52.06  Aligned_cols=145  Identities=12%  Similarity=0.047  Sum_probs=93.3  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..+......        .....++++.+...+.+.++.++..++.+|..+.... 
T Consensus       109 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~  179 (570)
T 6CRI_I          109 LCEPLRKCLK-DEDPYVRKTAAVCVAKLHDINAQ--------LVEDQGFLDTLKDLISDSNPMVVANAVAALSEIAESHP  179 (570)
T ss_dssp             SHHHHHHHHT-CSSHHHHHHHHHHHHHHHHHCHH--------HHHHHTHHHHHHHHHTSSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHhcC-CCCHHHHHHHHHHHHHHHHhChh--------hhhccchHHHHHHHhcCCCHHHHHHHHHHHHHHHhhCC
Confidence            4556667776 46778888999999988764321        1112456778888888888899999999999888652 


Q NP_000290.2     627 L-LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e-~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      . ........+++.+...+.+      .++.++..++.+|..+.......     ....++.+...+.+. ++.++..++
T Consensus       180 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~~~~~~~~~-----~~~~~~~l~~~l~~~-~~~vr~~a~  247 (570)
T 6CRI_I          180 SSNLLDLNPQSINKLLTALNE------CTEWGQIFILDCLANYMPKDDRE-----AQSICERVTPRLSHA-NSAVVLSAV  247 (570)
T ss_dssp             STTCCCCCHHHHHHHHHHHTT------SCHHHHHHHHHHTTTCCCSSHHH-----HHHHHHHHGGGGGBS-CHHHHHHHH
T ss_pred             CcchhccCHHHHHHHHHHhhc------CCHHHHHHHHHHHHHhCCCCHHH-----HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            1 1111112355555555554      25677778888888877542211     112455556666655 677788888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .++..+..
T Consensus       248 ~~l~~l~~  255 (570)
T 6CRI_I          248 KVLMKFME  255 (570)
T ss_dssp             HHHHHHTT
T ss_pred             HHHHHHHH
Confidence            87777764


No 386
>4QMI_B Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG domain; 1.9A {Homo sapiens}
Probab=82.55  E-value=0.084  Score=45.96  Aligned_cols=112  Identities=11%  Similarity=0.091  Sum_probs=68.9  Template_Neff=12.600

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      .+++.+...+.+.++.++..++.++..+...... ...+ ..+++.+...+.+      .++.++..++.++..++...+
T Consensus        19 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~-~~~~~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~   91 (240)
T 4QMI_B           19 KITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNI-GELPTALKGRLND------SNKILVQQTLNILQQLAVAMG   91 (240)
T ss_dssp             GSCHHHHHHHTCSSHHHHHHHHHHHHHHHHHHCSBCSCC-TTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHG
T ss_pred             hccHHHHHHhcCCCHHHHHHHHHHHHHHHcCchHhccch-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhc
Confidence            3455666667777788888888888888765211 1111 2345556666655      367888888888888876532


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ....... ...++.++..+.+. +..++..++.++..+....
T Consensus        92 ~~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~~  131 (240)
T 4QMI_B           92 PNIKQHV-KNLGIPIITVLGDS-KNNVRAAALATVNAWAEQT  131 (240)
T ss_dssp             GGGGGGC-CCCCHHHHHHTTCS-SHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHH-HHHHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHh
Confidence            2111111 23456666666655 5667777777777776553


No 387
>4QMJ_A Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG DOMAIN; 2.498A {Homo sapiens}
Probab=82.55  E-value=0.084  Score=45.96  Aligned_cols=112  Identities=11%  Similarity=0.091  Sum_probs=68.9  Template_Neff=12.600

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      .+++.+...+.+.++.++..++.++..+...... ...+ ..+++.+...+.+      .++.++..++.++..++...+
T Consensus        19 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~-~~~~~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~   91 (240)
T 4QMJ_A           19 KITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNI-GELPTALKGRLND------SNKILVQQTLNILQQLAVAMG   91 (240)
T ss_dssp             TSCHHHHHHHTCSSHHHHHHHHHHHHHHHHHHSSBCSCC-TTHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHHG
T ss_pred             hccHHHHHHhcCCCHHHHHHHHHHHHHHHcCchHhccch-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhc
Confidence            3455666667777788888888888888765211 1111 2345556666655      367888888888888876532


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ....... ...++.++..+.+. +..++..++.++..+....
T Consensus        92 ~~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~~  131 (240)
T 4QMJ_A           92 PNIKQHV-KNLGIPIITVLGDS-KNNVRAAALATVNAWAEQT  131 (240)
T ss_dssp             GGGGGGC-CCCCHHHHHGGGCS-SHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHH-HHHHHHHHHHhhcC-CHHHHHHHHHHHHHHHHHh
Confidence            2111111 23456666666655 5667777777777776553


No 388
>6MZG_E Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: GTP, GDP; 3.208A {Sus scrofa}
Probab=82.53  E-value=0.084  Score=52.43  Aligned_cols=147  Identities=12%  Similarity=0.077  Sum_probs=92.8  Template_Neff=12.700

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQ--LIGLKEKGLPQIARLL-QSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~--~llie~giI~~Ll~LL-~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++.+...+. +.++.++..++..|..++.....   . ..  .. .-..+++.+...+ .+.++.++..++.++..++..
T Consensus       315 ~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~---~-~~~~~~-~~~~i~~~l~~~l~~d~~~~v~~~a~~~l~~l~~~  388 (554)
T 6MZG_E          315 PADFQTRIS-STKWKDRVEALEEIHNNVLKPVK---K-LAHKNQ-DYSDYLRVLANVIQKDANVQAVTIAANSVQLLCNS  388 (554)
T ss_dssp             CSTTTTTTT-CSCHHHHHHHHHHCCCCCCTTCS---C-BCCSSC-CTHHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHH
T ss_pred             CHHHHHHhc-CCCHHHHHHHHHHHHHhhhcchh---H-HhccCC-cHHHHHHHHHHHHccccHHHHHHHHHHHHHHHHHH
Confidence            344666666 46677888899999888764221   0 00  01 1135677777777 777888999999999988865


Q NP_000290.2     626 P-LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       626 ~-e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      . .. .......+++.+...+.+      .+..++..++.+|..++....       ...+++.+...+.+. ++.++..
T Consensus       389 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~l~~~~~-------~~~~~~~l~~~l~~~-~~~vr~~  454 (554)
T 6MZG_E          389 LRSNFTRSYGAIVLVPLLERTKE------KKPSVNEAICSALDAVATYCG-------FDDCLEETLNYMKHK-TPQVRIE  454 (554)
T ss_dssp             STTCCSSHHHHHHHHHHHHGGGC------CCHHHHHHHHHHHHHHHTTSS-------SSSHHHHHHHHHTCS-CHHHHHH
T ss_pred             hhccccHHHHHhhHHHHHHHhhh------ccHHHHHHHHHHHHHHHHHcC-------HHHHHHHHHHHhcCC-CHHHHHH
Confidence            1 11 101112356666666655      256788888888888876421       123455666666554 6778888


Q NP_000290.2     704 ARLLLSDMWSSK  715 (747)
Q Consensus       704 AL~aLsnL~~~~  715 (747)
                      ++.+|..++...
T Consensus       455 ~~~~l~~l~~~~  466 (554)
T 6MZG_E          455 CTKFLTRMLQGW  466 (554)
T ss_dssp             HHHHHHHHHHTC
T ss_pred             HHHHHHHHHccC
Confidence            888888776543


No 389
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=82.32  E-value=0.085  Score=51.84  Aligned_cols=147  Identities=13%  Similarity=0.119  Sum_probs=94.4  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.+|..+......       .. ....+++.+...+.+.++.++..++.++..+....
T Consensus       164 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~  234 (588)
T 1B3U_A          164 ELRQYFRNLCS-DDTPMVRRAAASKLGEFAKVLEL-------DN-VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL  234 (588)
T ss_dssp             HHHHHHHHHHT-CSCHHHHHHHHHHHHHHHHTSCH-------HH-CCCCCHHHHHHHHTCSCHHHHTTHHHHHHHHHHHS
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHHHcCh-------hh-hhhhhHHHHHHHhcCCCHHHHHHHHHHHHHHHHhC
Confidence            35566667776 46778888898888888763221       11 12456677777777778888999999888887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ... .....+++.+..++.+      .++.++..++.++..+....+.   .......++.+...+.+. ++.++..++.
T Consensus       235 ~~~-~~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~~~~~~~~---~~~~~~~~~~l~~~l~~~-~~~~r~~a~~  303 (588)
T 1B3U_A          235 PQE-DLEALVMPTLRQAAED------KSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDC-EAEVRAAASH  303 (588)
T ss_dssp             CHH-HHHHHTHHHHHHHHTC------SSHHHHHHHHHTHHHHHHHHCH---HHCCCCCHHHHHHHHTCS-SHHHHHHHHH
T ss_pred             CHH-HHHHHHHHHHHHHHhC------CCHHHHHHHHhhHHHHHHHHCC---CCCHHhHHHHHHHHhccC-HHHHHHHHHH
Confidence            111 1112345556666655      3677888888888888754221   111224566666666655 6778888888


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      ++..+..
T Consensus       304 ~l~~l~~  310 (588)
T 1B3U_A          304 KVKEFCE  310 (588)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8877765


No 390
>2OF3_A ZYG-9; Multifunctional macromolecule, Kinetochore, microtubule, XMAP215; 1.9A {Caenorhabditis elegans}
Probab=81.96  E-value=0.098  Score=48.11  Aligned_cols=150  Identities=9%  Similarity=-0.036  Sum_probs=91.9  Template_Neff=11.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....  .........-..+++.++..+.+.+..++..+..+|..+.....
T Consensus        88 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~--~~~~~~~~~~~~ll~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  164 (266)
T 2OF3_A           88 LLKWCTLRFF-ETNPAALIKVLELCKVIVELIRD--TETPMSQEEVSAFVPYLLLKTGEAKDNMRTSVRDIVNVLSDVVG  164 (266)
T ss_dssp             HHHHHHHHTT-SCCHHHHHHHHHHHHHHHHHHHH--TTCCCCHHHHHHHHHHHHHGGGCSSHHHHHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHHh-CCCHHHHHHHHHHHHHHHHHHHh--CCCCCCHHHHHhHHHHHHHHhCCCcHHHHHHHHHHHHHHHHhhC
Confidence            3455555666 46677888888888888764221  00000000013456677777777777788888888887765421


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                      .     ..+++.+...+.+      .++.++..++.+|..+...........  ..+++.+...+.+. ++.++..++.+
T Consensus       165 ~-----~~~~~~l~~~l~~------~~~~~r~~~l~~l~~~~~~~~~~~~~~--~~ii~~l~~~l~d~-~~~VR~~a~~~  230 (266)
T 2OF3_A          165 P-----LKMTPMLLDALKS------KNARQRSECLLVIEYYITNAGISPLKS--LSVEKTVAPFVGDK-DVNVRNAAINV  230 (266)
T ss_dssp             H-----HHHHHHHHHGGGC------SCHHHHHHHHHHHHHHHHHHCSGGGGG--GCHHHHHGGGGGCS-SHHHHHHHHHH
T ss_pred             H-----HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCccccc--ChHHHHHHHHHcCC-CHHHHHHHHHH
Confidence            1     1234445555544      357778888888888775432211111  34667777777766 78899999999


Q NP_000290.2     708 LSDMWSS  714 (747)
Q Consensus       708 LsnL~~~  714 (747)
                      +..+...
T Consensus       231 l~~l~~~  237 (266)
T 2OF3_A          231 LVACFKF  237 (266)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            8888754


No 391
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=81.77  E-value=0.092  Score=51.50  Aligned_cols=147  Identities=13%  Similarity=0.130  Sum_probs=94.5  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.+...+. +.++.++..++.+|..+......      . . ....+++.+...+.+.++.++..++.++..+....
T Consensus       160 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~  230 (584)
T 4I5L_D          160 ELRQYFRNLCS-DDTPMVRRAAASKLGEFAKVLEL------D-N-VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL  230 (584)
T ss_dssp             HHHHHHHHHHT-CSSHHHHHHHHHHHHHHHTTSCH------H-H-CCCCCHHHHHHHTTCSCHHHHTTHHHHHHHHHHHS
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHcCh------h-h-hhcchHHHHHHHhCCCCHHHHHHHHHHHHHHHHhC
Confidence            34566667776 46778888899888888764221      1 1 12456677777787778888999999988887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ... .....+++.+..++.+      .++.++..++.++..+....+.   .......++.+...+.+. ++.++..++.
T Consensus       231 ~~~-~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  299 (584)
T 4I5L_D          231 PQE-DLEALVMPTLRQAAED------KSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDC-EAEVRAAASH  299 (584)
T ss_dssp             CTT-THHHHTHHHHHHHHTC------SSHHHHHHHHHTHHHHHHHHHH---HHCCCCCHHHHHHHHTCS-SHHHHHHHHT
T ss_pred             CHH-HHHHHHHHHHHHHhhC------CCHHHHHHHHHHHHHHHHHHCC---CCChhhHHHHHHHHhcCC-cHHHHHHHHH
Confidence            111 1112345556666655      3677888888888888754221   111224566666666655 6778888888


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      ++..+..
T Consensus       300 ~l~~l~~  306 (584)
T 4I5L_D          300 KVKEFCE  306 (584)
T ss_dssp             THHHHHH
T ss_pred             HHHHHHH
Confidence            8887765


No 392
>4Y5J_A Mini spindles TOG3; XMAP215, TOG, microtubule polymerization; 2.303A {Drosophila melanogaster}
Probab=81.72  E-value=0.097  Score=46.19  Aligned_cols=71  Identities=13%  Similarity=0.043  Sum_probs=45.8  Template_Neff=12.300

Q NP_000290.2     548 AIRT-YLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIA---RLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~-LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll---~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      .++. ++..+. +.++.++..++..|..++.....     .... ....+++.+.   ..+.+.++.++..++.++..++
T Consensus        15 ~l~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~~~~-----~~~~-~~~~l~~~l~~l~~~l~d~~~~v~~~a~~~l~~l~   87 (248)
T 4Y5J_A           15 ILPAEILNGLV-DSNWKNRLAAVEQLLGEISGFDA-----KQAG-ISQILIRTISGRKPGLKEMNFQVLKFKLDIIRSVA   87 (248)
T ss_dssp             CCCHHHHHHHH-CSSHHHHHHHHHHHHHHGGGSCT-----TSTT-HHHHHHHHHHSSSSGGGCSSHHHHHHHHHHHHHHH
T ss_pred             hcCHHHHHhhc-CcCHHHHHHHHHHHHHHHccCch-----hccc-hHHHHHHHHhcCCCchhhccHHHHHHHHHHHHHHH
Confidence            4555 777776 46778888899999888764221     0111 1123444444   5666667788888888888887


Q NP_000290.2     624 RH  625 (747)
Q Consensus       624 ~~  625 (747)
                      ..
T Consensus        88 ~~   89 (248)
T 4Y5J_A           88 EN   89 (248)
T ss_dssp             HH
T ss_pred             Hh
Confidence            54


No 393
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=81.57  E-value=0.1  Score=53.70  Aligned_cols=137  Identities=17%  Similarity=0.119  Sum_probs=87.9  Template_Neff=12.000

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      +..++.++. +.+..++..++.+|..+....+.        .  ...+++.+...+.+.++.++..++.+|..+..... 
T Consensus        81 ~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~-  148 (627)
T 4P6Z_G           81 QLECLKLIA-SQKFTDKRIGYLGAMLLLDERQD--------V--HLLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEM-  148 (627)
T ss_dssp             HHHHHHHHT-SSSHHHHHHHHHHHHHHCCTTSC--------C--HHHHHHHHHHHHTCSSHHHHHHHHHHHHHHCCHHH-
T ss_pred             HHHHHHHHc-CCCCchhHHHHHHHHHHCCCChH--------H--HHHHHHHHHHHhhCCCHHHHHHHHHHHHhcCCHHH-
Confidence            344556666 46677777888888777653221        1  12345566666777778888888888887764211 


Q NP_000290.2     629 HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLL  708 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aL  708 (747)
                          ...+++.+..++.+      .++.++..++.+|..+....+...     ..+++.|...+.+. ++.++..++.++
T Consensus       149 ----~~~~~~~l~~~l~~------~~~~vr~~a~~~L~~l~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~l  212 (627)
T 4P6Z_G          149 ----CRDLAGEVEKLLKT------SNSYLRKKAALCAVHVIRKVPELM-----EMFLPATKNLLNEK-NHGVLHTSVVLL  212 (627)
T ss_dssp             ----HHHHHHHHHHHHTC------SCHHHHHHHHHHHHHHHHHCSGGG-----GGGHHHHTTCTTCC-CHHHHHHHHHHH
T ss_pred             ----HHHHHHHHHHHhhC------CCHHHHHHHHHHHHHHHHHCHHHH-----HHHHHHHHHHHhCC-CHHHHHHHHHHH
Confidence                12345666666665      367888889999988876433221     24566677777655 677888888888


Q NP_000290.2     709 SDMWS  713 (747)
Q Consensus       709 snL~~  713 (747)
                      ..+..
T Consensus       213 ~~~~~  217 (627)
T 4P6Z_G          213 TEMCE  217 (627)
T ss_dssp             HHHHH
T ss_pred             HHHHH
Confidence            77754


No 394
>5KC2_B Phosphatidylinositol 3-kinase VPS34 (E.C.2.7.1.137), Serine/threonine-protein; autophagy, phosphatidylinositol 3-kinase (PtdIns3K), endocytosis; 28.0A {Saccharomyces cerevisiae}
Probab=81.46  E-value=0.11  Score=61.49  Aligned_cols=126  Identities=13%  Similarity=0.064  Sum_probs=72.5  Template_Neff=9.500

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.|..++.+.++.++..++.+|..+....  ....+.. ..++.|+.++.+.++.++..++.+|..+..........+.
T Consensus       621 l~~L~~~l~d~~~~vR~~a~~al~~l~~~~--~~~~~~~-~~lp~L~~lL~d~~~~vr~~al~aL~~L~~~~~~~~~~~~  697 (1454)
T 5KC2_B          621 LSHLITYLNDKDPALRVSLIQTISGISILL--GTVTLEQ-YILPLLIQTITDSEELVVISVLQSLKSLFKTGLIRKKYYI  697 (1454)
T ss_pred             HHHHHHHccCCCHHHHHHHHHHHHHHHHhh--HHHHHHH-cCHHHHHHHhcCCCHHHHHHHHHHHHHHhhCCHHHHHHHH
Confidence            444555555566667777777776666432  1112222 2266777777776777788888888877653322222221


Q NP_000290.2     327 RQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSSTDELKEELIADALPVLADRV  379 (747)
Q Consensus       327 ~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~~~~~~~LvegiLe~Lv~LL  379 (747)
                        ..++.+..++. +.++.++..+..+|..|+...... .....+++.|+.+|
T Consensus       698 --~~l~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~~-~~~~~~~~~L~~~L  746 (1454)
T 5KC2_B          698 --DISKTTSPLLL-HPNNWIRQFTLMIIIEIINKLSKA-EVYCILYPIIRPFF  746 (1454)
T ss_pred             --HHHHHHHHHHC-CCCHHHHHHHHHHHHHHhcCCCCH-HHHcChHHHHHHHh
Confidence              25556666665 457778888888888877643221 11134555555555


No 395
>6MZG_E Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: GTP, GDP; 3.208A {Sus scrofa}
Probab=81.15  E-value=0.1  Score=51.71  Aligned_cols=151  Identities=11%  Similarity=0.102  Sum_probs=93.6  Template_Neff=12.700

Q NP_000290.2     550 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR-LLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       550 ~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~-LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      +.+...+. +.++.++..++.+|..++..... ........ ....+++.++. ++.+.++.++..++.+|..++.....
T Consensus        57 ~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~-~~~~~l~~l~~~~~~~~~~~vr~~a~~~L~~l~~~~~~  133 (554)
T 6MZG_E           57 ELFASYIV-DSNVVAQENAIIALHTLLEYISQ-VPNVSTSK-LRLQWIPPLVEKGLSSSRAATKAKATDCIMLLTQSDTS  133 (554)
T ss_dssp             HHHHHHTT-CSSHHHHHHHHHHHHHHHHHTCS-SSCCTHHH-HHHHHHHHHCCCCCSCSCHHHHHHHHHHHHHHHHTSSS
T ss_pred             HHHHHhcC-CccHHHHHHHHHHHHHHHHHHhc-CCCCCcHH-HHHhcHHHHHHHhccCCcHHHHHHHHHHHHHHHhcccc
Confidence            55666776 47788899999999988764221 00000001 11345666666 45666788889999999888754111


Q NP_000290.2     629 HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK---QYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~---~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                          ...+++.+...+.+      .++.++..++.+|..++........   ......+++.+...+.+. ++.++..++
T Consensus       134 ----~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~~~~~~~~~~~~~~~~~i~~~l~~~l~~~-~~~vr~~a~  202 (554)
T 6MZG_E          134 ----IQQTVNLMLPSLSN------KLPRLVSSCVKCLATIIEEFGFINVSDINILLSEILEPLPKLSSHA-DRNVRSETM  202 (554)
T ss_dssp             ----SHHHHHHHSGGGGC------SCHHHHHHHHHHHHHHHHHTCSCSCSCHHHHHHHHHSSHHHHTTCS-SHHHHHHHH
T ss_pred             ----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCCccccccccHHHHHHHHHHHhhcC-CHHHHHHHH
Confidence                11244555555554      3677888899999888764221110   001234567777777766 788999999


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       203 ~~l~~l~~~  211 (554)
T 6MZG_E          203 NLILQIYKW  211 (554)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            998888754


No 396
>6MZE_Z Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: MG, GTP, GDP; 3.6A {Sus scrofa}
Probab=81.14  E-value=0.1  Score=51.20  Aligned_cols=108  Identities=11%  Similarity=0.069  Sum_probs=63.0  Template_Neff=12.900

Q NP_000290.2     600 IARLLQSGNSDVVRSGASLLSNMSRHPL-LHR---VMGNQVFPEVTRLL-TSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       600 Ll~LL~s~d~eVr~~AL~aLsnLa~~~e-~~~---ll~~giI~~Ll~LL-~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      +...+.+.+..++..++.+|..++.... ...   .....+++.+...+ .+      .++.++..++.++..++.....
T Consensus       300 l~~~l~~~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~d------~~~~v~~~a~~~l~~l~~~~~~  373 (536)
T 6MZE_Z          300 FQTRISSTKWKDRVEALEEIHNNVLKPVKKLAHKNQDYSDYLRVLANVIQKD------ANVQAVTIAANSVQLLCNSLRS  373 (536)
T ss_dssp             GHHHHSCSSHHHHHHHHHHCCCCCCSSCSCBCCTTCCCTTTHHHHHHHHHHC------SCHHHHHHHHHHHHHHHHHTTT
T ss_pred             HHHHhhcCCHHHHHHHHHHHHHHhhccchhhccCCCCHHHHHHHHHHHHhcC------chHHHHHHHHHHHHHHHHHccc
Confidence            4455555667778888888888775411 100   11123556666666 54      3678888899999888764322


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      .........+++.++..+.+. +..++..++.+|..++..
T Consensus       374 ~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~~~l~~l~~~  412 (536)
T 6MZE_Z          374 NFTRSYGAIVLVPLLERTKEK-KPSVNEAICSALDAVATY  412 (536)
T ss_dssp             CCSSHHHHHHHHHHHHHTTCC-CHHHHHHHHHHHHHHHHT
T ss_pred             cccHHHHHHHHHHHHHHhhcc-CHHHHHHHHHHHHHHHHh
Confidence            111011123455666666554 566777777777776654


No 397
>6RXU_UJ Periodic tryptophan protein 2-like protein; ribosome, ribosome biogenesis, rRNA; HET: GTP; 3.5A {Chaetomium thermophilum}
Probab=80.93  E-value=0.12  Score=62.49  Aligned_cols=152  Identities=9%  Similarity=0.051  Sum_probs=85.8  Template_Neff=9.700

Q NP_000290.2     548 AIRTYLNLMGKS-----KKDATLEACAGALQNLTASKGLMSSGMSQ--LIGLKEKGLPQIARLLQSG--------NSDVV  612 (747)
Q Consensus       548 ~I~~LL~LL~ss-----~d~eVr~~AL~aL~nLs~~s~~~s~~~~~--~llie~giI~~Ll~LL~s~--------d~eVr  612 (747)
                      +++.++..+...     .+..++..++.+|..++.....   ....  ..  -..+++.|...+...        ...++
T Consensus      1625 il~~ll~~L~~~~~~~~~~~~v~~~~l~~L~~l~~~~~~---~~~~~~~~--~~~ll~~L~~~L~~~~~~~~~~~~~~v~ 1699 (1802)
T 6RXU_UJ        1625 IVDASVKALKAVDFAVPEERNLWKRVLCTLAKCFEHDQD---GFWQAPAH--FGAVAPVLVEQFLRAEGQVTATNVNDVI 1699 (1802)
T ss_pred             HHHHHHHHHhcCCCCCCCCHHHHHHHHHHHHHHHHHhCh---hhhcChhH--HHHHHHHHHHHHhCCCCCCCccccHHHH
Confidence            345555555521     2456777788888877764221   0000  11  134556666666532        23567


Q NP_000290.2     613 RSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      ..++.+++.++.......+. ..+++.++..+.+      .++.++..++.++..++.........+. ..+++.+...+
T Consensus      1700 ~~ai~~L~~l~~~~~~~~~~-~~l~~~ll~~l~~------~~~~vR~~al~~L~~l~~~~g~~~~~~l-~~ii~~L~elL 1771 (1802)
T 6RXU_UJ        1700 QDVVPAVVELAAAVESQEHY-KEINTALLKHLRN------GSPGVRLAVVKCQQAITAKLGEDWLHLL-PEMLPYISELQ 1771 (1802)
T ss_pred             HHHHHHHHHHHHHhCCchHH-HhHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHHcHhhHHhH-HHHHHHHHHHh
Confidence            77888888877531111111 1234445555544      3567888999999988765332222222 24567777777


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++. ++.++..+..++..+..
T Consensus      1772 eD~-d~~V~~~a~~~l~~l~~ 1791 (1802)
T 6RXU_UJ        1772 DDD-DEVVERENRRWIVGIEE 1791 (1802)
T ss_pred             cCC-CHHHHHHHHHHHHHHHH
Confidence            766 77788888777776654


No 398
>5FVM_B SERINE/THREONINE-PROTEIN KINASE TOR2, TARGET OF; TRANSFERASE, CRYO-EM, TOR, LST8, MTOR; 6.7A {KLUYVEROMYCES MARXIANUS}
Probab=80.75  E-value=0.12  Score=63.47  Aligned_cols=147  Identities=12%  Similarity=0.092  Sum_probs=75.7  Template_Neff=11.500

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.+...+. +  ..++..++.++..++.....     ....+ -..+++.++..+.+.+..++..++.++..+.....
T Consensus      1008 i~~~l~~~l~-~--~~vr~~a~~~l~~l~~~~~~-----~~~~~-~~~ll~~l~~~l~~~~~~~r~~a~~~l~~l~~~~~ 1078 (2471)
T 5FVM_B         1008 IVDVISEFFP-V--LKLQLTIISVIESLSRALEG-----EFNPH-LPTILSLFLDVLEKDQSNKKVVSVRILKSLVVFGP 1078 (2471)
T ss_dssp             HHHTTC------------CTHHHHHHHHHTTSSC-----CHHHH-HHHHHHHHHHHHC----CCHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHHcc-c--hhHHHHHHHHHHHHHHHccc-----ChHHH-HHHHHHHHHHHHccCCCCcHHHHHHHHHHHHHHhh
Confidence            3444555444 1  45666778888877754221     01111 23566777777776666677777777776654321


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      . ...+ ..+++.+...+.+      .++.++..++.+|..++.....  .. ....++..++..+.+. ++.++..++.
T Consensus      1079 ~~~~~l-~~il~~l~~~l~~------~~~~vr~~al~~l~~l~~~~~~--~~-~~~~i~~~l~~~l~~~-~~~vr~~a~~ 1147 (2471)
T 5FVM_B         1079 HLEEYV-HLVLPTIIKLSEF------SSGNLKKAAIITIGRLSKNVNA--LE-MSSRIVQALVRVLNTS-ETEYVKATMN 1147 (2471)
T ss_dssp             SCCCHH-HHHHHHHHTTC---------CCHHHHHHHHHHHHHHHC-CC--HH-HHHHHHHHHHHHCC---CTHHHHHHHH
T ss_pred             hHHHHH-HHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCCh--HH-HHHHHHHHHHHHHcCC-ChHHHHHHHH
Confidence            1 1111 2355666666655      2567888888888888754221  11 1124566666777655 6677888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|..++..
T Consensus      1148 ~l~~l~~~ 1155 (2471)
T 5FVM_B         1148 TLSLLLLQ 1155 (2471)
T ss_dssp             HHHHHHHC
T ss_pred             HHHHHHHH
Confidence            88777643


No 399
>6GWC_C Tubulin alpha chain, Tubulin beta; microtubule, ARTIFICIAL PROTEIN, ALPHAREP, cytoskeleton; HET: GTP, MES, PGE; 2.6A {Ovis aries}
Probab=80.69  E-value=0.11  Score=45.32  Aligned_cols=49  Identities=8%  Similarity=0.093  Sum_probs=29.6  Template_Neff=12.200

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.+|..+...           ..++.+..++.+. ++.++..++.++..+...
T Consensus       120 ~~~~r~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~  168 (232)
T 6GWC_C          120 DTTVRRIAATALGKIGDE-----------RAVEPLIKALKDE-DAAVRLTAARALGEIGDE  168 (232)
T ss_pred             CHHHHHHHHHHHHHhccc-----------chHHHHHHHhcCC-CHHHHHHHHHHHHHhCCh
Confidence            455556666666555321           2344455566655 677888888888877653


No 400
>1OYZ_A X-RAY STRUCTURE OF YB61_HAEIN NORTHEAST; STRUCTURAL GENOMICS, PSI, Protein Structure; 2.1A {Escherichia coli} SCOP: a.118.1.16
Probab=80.56  E-value=0.11  Score=46.13  Aligned_cols=64  Identities=13%  Similarity=0.063  Sum_probs=32.1  Template_Neff=12.700

Q NP_000290.2     549 IRTYLN-LMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       549 I~~LL~-LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ++.+.. ++. +.++.++..++.+|..+....+.          .....++.+...+.+.++.++..++.+|..+.
T Consensus        92 ~~~l~~~~l~-~~~~~vr~~a~~~l~~~~~~~~~----------~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~~~  156 (280)
T 1OYZ_A           92 FNILNNMALN-DKSACVRATAIESTAQRCKKNPI----------YSPKIVEQSQITAFDKSTNVRRATAFAISVIN  156 (280)
T ss_dssp             HHHHHHHHHH-CSCHHHHHHHHHHHHHHHHHCGG----------GHHHHHHHHHHHTTCSCHHHHHHHHHHHHTC-
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhcCcc----------cChhHHHHHHHHhcCCCHHHHHHHHHHHHhhc
Confidence            344444 444 34556666666666665532110          11233445555555555666666666665544


No 401
>6GX7_F Tubulin alpha chain, Tubulin beta; microtubule, ALPHAREP, CELL CYCLE, COPN; HET: MES, PGE, SO4, GOL, GTP; 3.19A {Ovis aries}
Probab=80.46  E-value=0.12  Score=44.09  Aligned_cols=122  Identities=14%  Similarity=0.214  Sum_probs=55.9  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++..+..+..                ...++.+..++.+.++.++..++.++..+...  
T Consensus        46 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--  106 (201)
T 6GX7_F           46 AVEPLIKALK-DEDPWVRREAAGALGQIGD----------------ERAVEPLIKALKDEDRYVRRIAARALGKIGDE--  106 (201)
T ss_dssp             GHHHHHHHTT-CSSHHHHHHHHHHHHHHTC----------------GGGHHHHHHHTTCSSHHHHHHHHHHHHHHTCG--
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHCC----------------HHHHHHHHHHhcCCCHHHHHHHHHHHhhcCCh--
Confidence            3444555554 2445555555555544321                11233344445555555666666666555421  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.++..+...           ..++.+..++.+. +..++..++.+
T Consensus       107 -------~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~  161 (201)
T 6GX7_F          107 -------RAVEPLIKALKD------EDWQVREDAAKALGQIGDE-----------RAVEPLIKALKDE-DTTVRLEAALA  161 (201)
T ss_dssp             -------GGHHHHHHHTTC------SSHHHHHHHHHHHHHHTCG-----------GGHHHHHHHTTCS-SHHHHHHHHHH
T ss_pred             -------hhHHHHHHHhhc------CCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHHhCC-CHHHHHHHHHH
Confidence                   122333333433      2345555555555554321           1233333444433 45555566666


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      +..+..
T Consensus       162 l~~~~~  167 (201)
T 6GX7_F          162 LGKIGG  167 (201)
T ss_dssp             HHHHCS
T ss_pred             HHhhcc
Confidence            555543


No 402
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=80.40  E-value=0.11  Score=50.67  Aligned_cols=147  Identities=13%  Similarity=0.119  Sum_probs=93.6  Template_Neff=13.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+..++. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+....
T Consensus       158 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~~~~~~~~~r~~a~~~l~~l~~~~  228 (582)
T 2NYL_A          158 ELRQYFRNLCS-DDTPMVRRAAASKLGEFAKVLEL-------DN-VKSEIIPMFSNLASDEQDSVRLLAVEACVNIAQLL  228 (582)
T ss_dssp             HHHHHHHHHHS-CSCHHHHHHHHHHHHHHHTTSCH-------HH-CCCCCHHHHHHHTSCSCHHHHHHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHcc-CCCHHHHHHHHHHHHHHHHHcCh-------hh-hHhhHHHHHHHHhhCCCHHHHHHHHHHHHHHHHHC
Confidence            35566667776 46778888899988888763221       11 12456677777777777888888988888887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ... .....+++.+...+.+      .++.++..++.++..+....+.   .......++.+...+.+. ++.++..++.
T Consensus       229 ~~~-~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~~~~~~~~---~~~~~~~~~~l~~~l~~~-~~~v~~~a~~  297 (582)
T 2NYL_A          229 PQE-DLEALVMPTLRQAAED------KSWRVRYMVADKFTELQKAVGP---EITKTDLVPAFQNLMKDC-EAEVRAAASH  297 (582)
T ss_dssp             CHH-HHTTTTHHHHHHHHHC------SSHHHHHHHHHTHHHHHHHHCS---HHCCCCCHHHHHHHHTCS-SHHHHHHHHT
T ss_pred             CHH-HHHHHHHHHHHHHhcC------CCHHHHHHHHHhHHHHHHHHCC---CCCHhhhHHHHHHHhcCC-hHHHHHHHHH
Confidence            111 1112345556666655      3677888888888888754221   111223566666666655 6778888888


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      ++..+..
T Consensus       298 ~l~~~~~  304 (582)
T 2NYL_A          298 KVKEFCE  304 (582)
T ss_dssp             THHHHHH
T ss_pred             HHHHHHH
Confidence            8877765


No 403
>5VJC_B Protein mini spindles; TOG, HEAT Repeat, Tubulin, CELL; 2.0A {Drosophila melanogaster}
Probab=80.32  E-value=0.12  Score=47.18  Aligned_cols=72  Identities=13%  Similarity=0.027  Sum_probs=44.4  Template_Neff=11.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .+.+.+...+. +.++.++..++..|..++.....     ...... ..++..+...+.+.++.++..++.++..++..
T Consensus        50 ~~~~~l~~~l~-~~~~~~r~~a~~~L~~~~~~~~~-----~~~~~~-~~l~~~l~~~l~d~~~~vr~~a~~~l~~l~~~  121 (271)
T 5VJC_B           50 NVNKALIANMF-HDDFRYHLKVIEQLSEDLAGNSK-----ALVCNL-DLILKWLTLRFYDTNPSVLIKGLEYLVQVFQV  121 (271)
T ss_dssp             TCCHHHHHHHT-CSCHHHHHHHHHHHHHHTTTCHH-----HHHHTH-HHHHHHHHHHTTSSCHHHHHHHHHHHHHHHHH
T ss_pred             cCCHHHHHhcc-CCCHHHHHHHHHHHHHHHhcCHH-----HHHHHH-HHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHH
Confidence            34566777776 46777888888888888764321     011111 23344455555566777888888888877654


No 404
>6RXV_UJ Periodic tryptophan protein 2-like protein; ribosome, ribosome biogenesis, rRNA; HET: GTP; 4.0A {Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)}
Probab=80.28  E-value=0.13  Score=62.13  Aligned_cols=152  Identities=9%  Similarity=0.051  Sum_probs=86.0  Template_Neff=9.700

Q NP_000290.2     548 AIRTYLNLMGKS-----KKDATLEACAGALQNLTASKGLMSSGMSQ--LIGLKEKGLPQIARLLQSG--------NSDVV  612 (747)
Q Consensus       548 ~I~~LL~LL~ss-----~d~eVr~~AL~aL~nLs~~s~~~s~~~~~--~llie~giI~~Ll~LL~s~--------d~eVr  612 (747)
                      +++.++..+...     .+..++..++.+|..++.....   ....  ..  -..+++.|...+...        ...++
T Consensus      1625 il~~ll~~L~~~~~~~~~~~~v~~~al~~L~~l~~~~~~---~~~~~~~~--~~~il~~L~~~L~~~~~~~~~~~~~~v~ 1699 (1802)
T 6RXV_UJ        1625 IVDASVKALKAVDFAVPEERNLWKRVLCTLAKCFEHDQD---GFWQAPAH--FGAVAPVLVEQFLRAEGQVTATNVNDVI 1699 (1802)
T ss_pred             HHHHHHHHHHhcCCCChHHHHHHHHHHHHHHHHHhcCCC---CcccChhH--HHhHHHHHHHHHHhhcCCCCCccHHHHH
Confidence            345555555521     2456777788888877764221   0000  11  134556666666532        23567


Q NP_000290.2     613 RSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLC  692 (747)
Q Consensus       613 ~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL  692 (747)
                      ..++.+++.++.......+. ..+++.++..+.+      .++.++..++.++..++.........+. ..+++.+...+
T Consensus      1700 ~~ai~~L~~l~~~~~~~~~~-~~l~~~ll~~l~~------~~~~vR~~al~~L~~l~~~~g~~~~~~l-~eii~~L~elL 1771 (1802)
T 6RXV_UJ        1700 QDVVPAVVELAAAVESQEHY-KEINTALLKHLRN------GSPGVRLAVVKCQQAITAKLGEDWLHLL-PEMLPYISELQ 1771 (1802)
T ss_pred             HHHHHHHHHHHHHcCCHHHH-HHHHHHHHHHccC------CCHHHHHHHHHHHHHHHHHHCHhHHhhh-hHHHHHHHHHh
Confidence            77888888877531111111 1234445555544      3567888999999988765332222222 24567777777


Q NP_000290.2     693 RSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       693 ~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      ++. ++.++..+..++..+..
T Consensus      1772 eD~-d~~V~~~a~~~l~~l~~ 1791 (1802)
T 6RXV_UJ        1772 DDD-DEVVERENRRWIVGIEE 1791 (1802)
T ss_pred             cCC-CHHHHHHHHHHHHHHHH
Confidence            766 77788888777776654


No 405
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=80.24  E-value=0.11  Score=50.76  Aligned_cols=109  Identities=15%  Similarity=0.189  Sum_probs=68.2  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.+...+. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+... 
T Consensus       238 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  308 (584)
T 4I5L_D          238 LVMPTLRQAAE-DKSWRVRYMVADKFTELQKAVGP-------EI-TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENL  308 (584)
T ss_dssp             HTHHHHHHHHT-CSSHHHHHHHHHTHHHHHHHHHH-------HH-CCCCCHHHHHHHHTCSSHHHHHHHHTTHHHHHHTS
T ss_pred             HHHHHHHHHhh-CCCHHHHHHHHHHHHHHHHHHCC-------CC-ChhhHHHHHHHHhcCCcHHHHHHHHHHHHHHHHhc
Confidence            35566666776 46778888888888887754221       11 1245667777778777788899999999888764 


Q NP_000290.2     626 PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ... . ......+++.+...+.+      .+..++..++.++..+..
T Consensus       309 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~  349 (584)
T 4I5L_D          309 SADCRENVIMSQILPCIKELVSD------ANQHVKSALASVIMGLSP  349 (584)
T ss_dssp             CTTTHHHHCCCCCHHHHHHHHTC------SCHHHHHHHHTTGGGGHH
T ss_pred             CccchhhHHHHhHHHHHHHHccC------CCHHHHHHHHHHHHHHHH
Confidence            111 1 11123355555555554      245666777777766654


No 406
>1IBR_B RAN  IMPORTIN BETA SUBUNIT; SMALL GTPASE  NUCLEAR TRANSPORT; HET: GNP; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=80.23  E-value=0.12  Score=49.62  Aligned_cols=156  Identities=10%  Similarity=0.042  Sum_probs=86.8  Template_Neff=12.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM------------SSGMSQ----LIGLKEKGLPQIARLLQSG-----  607 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~------------s~~~~~----~llie~giI~~Ll~LL~s~-----  607 (747)
                      ++.+...+. +.++.++..++.++..++......            ......    .. .-..+++.+...+.+.     
T Consensus       261 ~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~l~~~l~~~l~~~~~~~~  338 (462)
T 1IBR_B          261 FAITIEAMK-SDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKG-ALQYLVPILTQTLTKQDENDD  338 (462)
T ss_dssp             HHHHHHHHH-CSSHHHHHHHHHHHHHHHHHHHHHHHHHCCTTCSSSCSSCCCCCHHHH-HHHHHHHHHHHHTTCCCSSCC
T ss_pred             HHHHHHHHh-cCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCcchhhHHhHHH-HHHHHHHHHHHhcccCCCCCC
Confidence            555666666 356777778888888776531000            000000    00 0123344444444433     


Q NP_000290.2     608 --NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSM  684 (747)
Q Consensus       608 --d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~gi  684 (747)
                        +..++..+..++..++.....  .....+++.+...+.+      .++.++..++.++..++...+. ...... ..+
T Consensus       339 ~~~~~~r~~a~~~l~~l~~~~~~--~~~~~~~~~l~~~l~~------~~~~~r~~al~~l~~l~~~~~~~~~~~~~-~~~  409 (462)
T 1IBR_B          339 DDDWNPCKAAGVCLMLLATCCED--DIVPHVLPFIKEHIKN------PDWRYRDAAVMAFGCILEGPEPSQLKPLV-IQA  409 (462)
T ss_dssp             TTCCSHHHHHHHHHHHHHHHTTT--THHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHTSSSSCTTTTCTTT-TTH
T ss_pred             CCCCCHHHHHHHHHHHHHHhccC--ccHHhHHHHHHHhccC------CCHHHHHHHHHHHHHHHhCCCHHHHHHHH-HHH
Confidence              445667777777777654111  0111234444455544      3677888999999988764332 111111 235


Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      ++.+...+.+. ++.++..++.++..++....
T Consensus       410 ~~~l~~~l~d~-~~~vr~~a~~~l~~l~~~~~  440 (462)
T 1IBR_B          410 MPTLIELMKDP-SVVVRDTAAWTVGRICELLP  440 (462)
T ss_dssp             HHHHHHGGGCS-CHHHHHHHHHHHHHHHHHGG
T ss_pred             HHHHHHHcCCC-CHHHHHHHHHHHHHHHHhCh
Confidence            66677777665 78899999999998876443


No 407
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=80.14  E-value=0.12  Score=50.76  Aligned_cols=109  Identities=15%  Similarity=0.181  Sum_probs=67.7  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+..++. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+....
T Consensus       242 ~~~~~l~~~l~-~~~~~~r~~~~~~l~~~~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~~r~~a~~~l~~l~~~~  312 (588)
T 1B3U_A          242 LVMPTLRQAAE-DKSWRVRYMVADKFTELQKAVGP-------EI-TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENL  312 (588)
T ss_dssp             HTHHHHHHHHT-CSSHHHHHHHHHTHHHHHHHHCH-------HH-CCCCCHHHHHHHHTCSSHHHHHHHHHHHHHHHHTS
T ss_pred             HHHHHHHHHHh-CCCHHHHHHHHhhHHHHHHHHCC-------CC-CHHhHHHHHHHHhccCHHHHHHHHHHHHHHHHHhC
Confidence            35566666776 46777888888888888754221       11 12456677777777777888889999988887641


Q NP_000290.2     627 -LL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       627 -e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                       .. . ......+++.+...+.+      .+..++..++.++..+..
T Consensus       313 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~  353 (588)
T 1B3U_A          313 SADCRENVIMSQILPCIKELVSD------ANQHVKSALASVIMGLSP  353 (588)
T ss_dssp             CTTTHHHHCCCCCHHHHHHHHTC------SCHHHHHHHHTTGGGGHH
T ss_pred             CcchhhhhhHHhHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence             11 1 11113345555555554      245666667777666654


No 408
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=80.03  E-value=0.13  Score=52.92  Aligned_cols=67  Identities=18%  Similarity=0.165  Sum_probs=48.8  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      +++.+..++. +.++.++..++.+|..+....+.        .  ...+++.|...+.+.++.++..++.++..++..
T Consensus       152 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~--------~--~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~  218 (627)
T 4P6Z_G          152 LAGEVEKLLK-TSNSYLRKKAALCAVHVIRKVPE--------L--MEMFLPATKNLLNEKNHGVLHTSVVLLTEMCER  218 (627)
T ss_dssp             HHHHHHHHHT-CSCHHHHHHHHHHHHHHHHHCSG--------G--GGGGHHHHTTCTTCCCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhh-CCCHHHHHHHHHHHHHHHHHCHH--------H--HHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHh
Confidence            4666777777 46778888899999888764221        1  135677777888777888888898888888654


No 409
>5NR4_A CLIP-associating protein 2; Microtubules, TOG domain, Tubulin, Structural; 1.198A {Homo sapiens}
Probab=79.96  E-value=0.12  Score=44.07  Aligned_cols=109  Identities=12%  Similarity=0.062  Sum_probs=69.2  Template_Neff=12.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++.++..+........... ...+++.+...+.+.+..++..++.++..+......   
T Consensus        51 ~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~---  126 (230)
T 5NR4_A           51 GKTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSY-VAMVIVALIDRMGDAKDKVRDEAQTLILKLMDQVAP---  126 (230)
T ss_dssp             HHHHHHHHHHHHCSSHHHHHHHHHHHHHHHHHHGGGGGGG-HHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHTSC---
T ss_pred             HHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHhhHHHHHH-HHHHHHHHHHHhccCCHHHHHHHHHHHHHHHHcCCC---
Confidence            3455666666666778888889999888876543221111 134566666666666677788888888777653210   


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ...+++.+...+. +.++.++..++.++..++..
T Consensus       127 ---~~~~~~~l~~~l~-~~~~~~r~~~~~~l~~l~~~  159 (230)
T 5NR4_A          127 ---PMYIWEQLASGFK-HKNFRSREGVCLCLIETLNI  159 (230)
T ss_dssp             ---HHHHHHHHGGGGG-CSCHHHHHHHHHHHHHHHHH
T ss_pred             ---HHHHHHHHHhcCC-CCCHHHHHHHHHHHHHHHHH
Confidence               1234555555665 45667888888888877753


No 410
>2P8Q_A Importin beta-1 subunit, Snurportin-1; HEAT repeat, IBB-domain, Importin, Karyopherin; 2.35A {Homo sapiens} SCOP: a.118.1.1
Probab=79.89  E-value=0.12  Score=54.05  Aligned_cols=154  Identities=11%  Similarity=0.064  Sum_probs=92.1  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|...+. +.+  +.++..++.+|..++.....   . .... ....+++.+...+.+.+  +.++..++.++..++
T Consensus       129 l~~~l~~~l~-~~~~~~~~~~~~~~~l~~l~~~~~~---~-~~~~-~~~~l~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (876)
T 2P8Q_A          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (876)
T ss_dssp             HHHHHHHHHH-CTTCCHHHHHHHHHHHHHHHHHSCT---T-SSST-THHHHHHHHHHHHCTTCSCHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHhh-CCCCCHHHHHHHHHHHHHHHHhcCH---H-HHHH-HHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            4566666666 344  56777888888877754221   0 0011 12456677777777665  788888999998887


Q NP_000290.2     624 RH-PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~-~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .. ... . ......+++.+...+.+      .++.++..++.+|..+...............+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~~~~~~~~~~~~~l~~~l~~~l~~~-~~~v  275 (876)
T 2P8Q_A          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (876)
T ss_dssp             GGCHHHHTCHHHHHHHHHHHHHHTTC------SSHHHHHHHHHHHHHHHHHCGGGTHHHCCCCCHHHHHHHHTCS-SHHH
T ss_pred             HHchhhccCHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhcHHHHHHhhhHHHHHHHHHHhcCC-hHHH
Confidence            64 111 1 11122344455555544      3567888899999888764332222112223566666667655 6778


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       276 ~~~a~~~l~~l~~~  289 (876)
T 2P8Q_A          276 ALQGIEFWSNVCDE  289 (876)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88888888777653


No 411
>4I5L_D PP2A A alpha subunit (9-589); EF Hand, Phosphatase, CDC6 (Substrate); HET: FGA, ACB, DAL, MLI, PEG, 1ZN, MAA; 2.43A {Microcystis aeruginosa}
Probab=79.88  E-value=0.12  Score=50.59  Aligned_cols=147  Identities=14%  Similarity=0.094  Sum_probs=80.2  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.+...+. +.++.++..++.++..+......      ..  .....++.+...+.+.++.++..++.++..+....
T Consensus       320 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~------~~--~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~  390 (584)
T 4I5L_D          320 QILPCIKELVS-DANQHVKSALASVIMGLSPILGK------DN--TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVI  390 (584)
T ss_dssp             CCHHHHHHHHT-CSCHHHHHHHHTTGGGGHHHHHH------HH--CCCCCHHHHHHHHTCSCHHHHHHHHTCCHHHHHHS
T ss_pred             hHHHHHHHHcc-CCCHHHHHHHHHHHHHHHHHhCC------cc--hHHHHHHHHHHHhcCCCHHHHHHHHHcHHHHHHHc
Confidence            45666666776 35667777888888777653211      11  12345666677777777778888888887776541


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .... ....+++.+...+.+      .+..++..++.++..+....+.   ......+++.+..++.+. ++.++..++.
T Consensus       391 ~~~~-~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  459 (584)
T 4I5L_D          391 GIRQ-LSQSLLPAIVELAED------AKWRVRLAIIEYMPLLAGQLGV---EFFDEKLNSLCMAWLVDH-VYAIREAATS  459 (584)
T ss_dssp             CHHH-HHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHCH---HHCCCCCHHHHHHHTTCS-SHHHHHHHHH
T ss_pred             ChHH-HHHhHHHHHHHHHHh------CCHHHHHHHHHHHHHHHHhcCh---HHhHHHHHHHHHHHHcCC-HHHHHHHHHH
Confidence            1111 112244445555544      2456666677777666543111   111112344444555444 5556666666


Q NP_000290.2     707 LLSDMWS  713 (747)
Q Consensus       707 aLsnL~~  713 (747)
                      +|..+..
T Consensus       460 ~l~~l~~  466 (584)
T 4I5L_D          460 NLKKLVE  466 (584)
T ss_dssp             HHHHHHH
T ss_pred             HHHHHHH
Confidence            6666554


No 412
>1QGR_A IMPORTIN BETA SUBUNIT, IMPORTIN ALPHA-2; TRANSPORT RECEPTOR, NUCLEAR IMPORT, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=79.85  E-value=0.12  Score=54.15  Aligned_cols=154  Identities=11%  Similarity=0.065  Sum_probs=92.3  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.|...+. +.+  +.++..++.+|..++.....   . .... ....+++.+...+.+.+  +.++..++.+|..++
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~~~~l~~l~~l~~~~~~---~-~~~~-~~~~l~~~l~~~l~~~~~~~~vr~~a~~~l~~l~  202 (876)
T 1QGR_A          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (876)
T ss_pred             HHHHHHHHHc-CCCCCHHHHHHHHHHHHHHHhhCCH---H-HHHH-HHHHHHHHHHHHhcCCCCCHHHHHHHHHHHHHHH
Confidence            4556666666 344  56777888888877754221   0 0111 12356677777777655  788888999998887


Q NP_000290.2     624 RHP-LL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~~-e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      ... .. . ......+++.+...+.+      .++.++..++.+|..++..............+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~i~~~l~~~~~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~-~~~v  275 (876)
T 1QGR_A          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (876)
T ss_pred             hhCCcccCChHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHhCHHHhhHhhHHhHHHHHHHHhCCC-CHHH
Confidence            652 11 1 11122344455555544      3577888899999888765332222111223566666667655 6778


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..++..
T Consensus       276 ~~~a~~~l~~l~~~  289 (876)
T 1QGR_A          276 ALQGIEFWSNVCDE  289 (876)
T ss_pred             HHHHHHHHHHHHHH
Confidence            88888888777654


No 413
>1B3U_A PROTEIN PHOSPHATASE PP2A, 65 KD; SCAFFOLD PROTEIN, PP2A, PHOSPHORYLATION, HEAT; 2.3A {Homo sapiens} SCOP: a.118.1.2
Probab=79.78  E-value=0.12  Score=50.60  Aligned_cols=146  Identities=14%  Similarity=0.095  Sum_probs=76.6  Template_Neff=13.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.+...+. +.++.++..++.++..+......      . . .....++.+...+.+.++.++..++.++..+....
T Consensus       324 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~~  394 (588)
T 1B3U_A          324 QILPCIKELVS-DANQHVKSALASVIMGLSPILGK------D-N-TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVI  394 (588)
T ss_dssp             CCHHHHHHHHT-CSCHHHHHHHHTTGGGGHHHHCH------H-H-CCCCCHHHHHHHHTCSCHHHHHHHHTTCHHHHHHS
T ss_pred             hHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHHCc------c-c-hHHhHHHHHHHHhcCCCHHHHHHHHhchHHHHHhc
Confidence            45566666676 35667777888888777653211      1 1 11345666677777777778888888887776541


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      .... ....+++.+...+.+      .+..++..++.++..+....+.   ......+++.+..++.+. +..++..++.
T Consensus       395 ~~~~-~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~---~~~~~~~~~~l~~~l~~~-~~~vr~~a~~  463 (588)
T 1B3U_A          395 GIRQ-LSQSLLPAIVELAED------AKWRVRLAIIEYMPLLAGQLGV---EFFDEKLNSLCMAWLVDH-VYAIREAATS  463 (588)
T ss_dssp             CHHH-HHHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHHCG---GGCCHHHHHHHHHGGGCS-SHHHHHHHHH
T ss_pred             CHHH-HHHHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhcCh---HHhHHHHHHHHHHHhcCC-hHHHHHHHHH
Confidence            1111 111234444444444      2455666666666666542111   111112333444444433 4455555555


Q NP_000290.2     707 LLSDMW  712 (747)
Q Consensus       707 aLsnL~  712 (747)
                      +|..+.
T Consensus       464 ~l~~l~  469 (588)
T 1B3U_A          464 NLKKLV  469 (588)
T ss_dssp             HHHHHH
T ss_pred             HHHHHH
Confidence            555544


No 414
>6MZE_Z Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: MG, GTP, GDP; 3.6A {Sus scrofa}
Probab=79.70  E-value=0.13  Score=50.52  Aligned_cols=152  Identities=11%  Similarity=0.094  Sum_probs=94.5  Template_Neff=12.900

Q NP_000290.2     550 RTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIAR-LLQSGNSDVVRSGASLLSNMSRHPLL  628 (747)
Q Consensus       550 ~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~-LL~s~d~eVr~~AL~aLsnLa~~~e~  628 (747)
                      +.+...+. +.++.++..++.+|..++..... ........ ....+++.|+. ++.+.++.++..++.+|..+......
T Consensus        57 ~~l~~~l~-d~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~-~~~~~l~~l~~~~~~~~~~~vr~~a~~~l~~l~~~~~~  133 (536)
T 6MZE_Z           57 ELFASYIV-DSNVVAQENAIIALHTLLEYISQ-VPNVSTSK-LRLQWIPPLVEKGLSSSRAATKAKATDCIMLLTQSDTS  133 (536)
T ss_dssp             HHHHHHHS-CSSHHHHHHHHHHHHHHHHHTSS-SCCTTHHH-HHHHHHHHHCCCCCSCSCHHHHHHHHHHHHHHHHHSSS
T ss_pred             HHHHHHhc-CchHHHHHHHHHHHHHHHHHhcc-CCCCCcHH-HHHhhHHHHHHhhccCCCHHHHHHHHHHHHHHhccCcc
Confidence            55666676 47788899999999888754211 00000011 12345666776 56667788899999999888764111


Q NP_000290.2     629 HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAK---QYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       629 ~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~---~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                          ...+++.+...+.+      .++.++..++.+|..++........   ......+++.+...+.+. ++.++..++
T Consensus       134 ----~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  202 (536)
T 6MZE_Z          134 ----IQQTVNLMLPSLSN------KLPRLVSSCVKCLATIIEEFGFINVSDINILLSEILEPLPKLSSHA-DRNVRSETM  202 (536)
T ss_dssp             ----SHHHHHHHSGGGGC------SCHHHHHHHHHHHHHHHHTTCSCSCTTHHHHHHHHHTTHHHHHTCS-SHHHHHHHH
T ss_pred             ----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHHHhCCCcccccccchHHHHHHHHHHhcCC-CHHHHHHHH
Confidence                11244555555554      3678888899999888764222110   001234567777777766 788999999


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..+....
T Consensus       203 ~~l~~l~~~~  212 (536)
T 6MZE_Z          203 NLILQIYKWF  212 (536)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            9988887543


No 415
>5F0N_A cohesin subunit Pds5, KLTH0D07062p; heat repeat cohesin subunit, cell; 3.2A {Lachancea thermotolerans}
Probab=79.14  E-value=0.17  Score=59.20  Aligned_cols=150  Identities=8%  Similarity=0.095  Sum_probs=100.7  Template_Neff=8.200

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|...|. +++..+|..|+.+|+.+....+.  .. ...  .....++.++..+.+.++.++..++.++..+....
T Consensus       271 ~vlp~L~~~L~-~~d~~vR~~Av~~Lg~l~~~~~~--~~-l~~--~~~~l~~~ll~rl~D~~~~VR~~av~~L~~i~~~~  344 (1175)
T 5F0N_A          271 SVTGLLYQLLC-SDNELFRESATKCVSKMLGTHSL--IN-FAV--AHSDTYKIWLSKMADISPHVRQAWVSEIPSILMSR  344 (1175)
T ss_dssp             GGHHHHHHHTT-CSSHHHHHHHHHHHHHHHTSCCS--SC-HHH--HTHHHHHHHHGGGSCSCHHHHHHHHTTHHHHHHHC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHccccc--cc-HHH--HcHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHcC
Confidence            36777888887 47788999999999988753210  00 011  12346667777788888999999999999887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..   ....+++.|...+.+      .++.++..++.+|..+.....  .........++.|...+.+. ++.+|..|+.
T Consensus       345 ~~---l~~~ii~~L~~~L~D------~d~~VR~~av~~L~~l~~~~~--~~~~~~~~ll~~L~~~l~D~-~~~VR~~A~~  412 (1175)
T 5F0N_A          345 SD---LSDDISKGLAKALID------SDHTVRLSAIQTFHEVPVKRL--WECLPNAAVFAGLVHLTRET-RRDLRDECID  412 (1175)
T ss_dssp             SS---CHHHHHHHHHHHHTC------SSHHHHHHHHGGGTSSCHHHH--HHHCCCHHHHHHHHTTTTCC-SHHHHHHHHH
T ss_pred             hh---hHHHHHHHHHHHhCC------CCHHHHHHHHHHHHhhhhhhh--hhcCCchHHHHHHHHHHhcC-CHHHHHHHHH
Confidence            11   112355666666766      378899999999988764311  01111134567777777776 7889999999


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|+.+...
T Consensus       413 aL~~l~~~  420 (1175)
T 5F0N_A          413 AVARIYTE  420 (1175)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            98887754


No 416
>4NEE_G AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=78.80  E-value=0.15  Score=48.94  Aligned_cols=115  Identities=12%  Similarity=0.097  Sum_probs=71.6  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+..++  . +.++.++..++.+|..+....+.        .+....+++.|...+.+.++.++..++.+|..+...
T Consensus       149 ~~~~l~~~l~~~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  219 (398)
T 4NEE_G          149 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  219 (398)
T ss_dssp             HTTHHHHHHHCS-SSCHHHHHHHHHHHHHHHHHCGG--------GSCCSSHHHHHHGGGGCSCHHHHHHHHHHHHHHHHH
T ss_pred             HHHhHHHHHhcC-CCCHHHHHHHHHHHHHHHHHChh--------hccccchHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            455666777  6 46778888999999988764221        111245677788888777888999999999988865


Q NP_000290.2     626 PL-LHRVMGNQVFPEVTRLLTSHTG-------NTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       626 ~e-~~~ll~~giI~~Ll~LL~s~s~-------~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      .. ........+++.+..++.+...       ....++.++..++.+|..+...
T Consensus       220 ~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~~~~~  273 (398)
T 4NEE_G          220 NPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPP  273 (398)
T ss_dssp             CGGGGTHHHHHHHHHHHHHHHCCTTTTGGGEETTEESHHHHHHHHHHHTTSCSC
T ss_pred             CHHHHHHHHHHHHHHHHHHHhcCCcCcccccccCCCCHHHHHHHHHHHHhCCCC
Confidence            21 1111112345555555543000       0001456777888888887754


No 417
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=78.75  E-value=0.14  Score=55.16  Aligned_cols=158  Identities=8%  Similarity=0.034  Sum_probs=93.7  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..++.....     ..... ...+++.|...+.+.++.++..++.+|+.++....
T Consensus       849 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  921 (1078)
T 3W3U_A          849 IWPMINTFLL-DNEPILVIFALVVIGDLIQYGGE-----QTASM-KNAFIPKVTECLISPDARIRQAASYIIGVCAQYAP  921 (1078)
T ss_dssp             GHHHHHHHHT-SSCHHHHHHHHHHHHHHHHHHGG-----GCHHH-HHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHSC
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcch-----hhHHH-HHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHCc
Confidence            3444555555 35667777888888887754221     01111 23567777888888888999999999999887621


Q NP_000290.2     628 -LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       628 -~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                       ........+++.|...+.........+..++..++.+|..+....+....  ....+++.++..+....++.++..++.
T Consensus       922 ~~~~~~~~~~l~~l~~~l~~~~~~~~~~~~vr~~a~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~~~~~~~~~~~~  999 (1078)
T 3W3U_A          922 STYADVCIPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIP--NVDTYTANWFKTLPTITDKEAASFNYQ  999 (1078)
T ss_dssp             TTTHHHHHHHHHHHHHHTC-CCTTSHHHHHHHHHHHHHHHHHHHHC--------CCHHHHHHHTTCCCCSCHHHHHHHHH
T ss_pred             cccHHhHHHHHHHHHHHHhCCCcccccccchHHHHHHHHHHHHHHcccCCC--ChhHHHHHHHHhCCcCCCHHHHHHHHH
Confidence             11111134566666666510000003678899999999998875332211  122456666666632226677888888


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|..++..
T Consensus      1000 ~l~~l~~~ 1007 (1078)
T 3W3U_A         1000 FLSQLIEN 1007 (1078)
T ss_dssp             HHHHHHHT
T ss_pred             HHHHHHHc
Confidence            88877754


No 418
>4NEE_B AP-2 complex subunit sigma, AP-2; clathrin Adaptor AP-2, HIV-1 Nef; 2.8841A {Rattus norvegicus}
Probab=78.75  E-value=0.15  Score=49.03  Aligned_cols=115  Identities=12%  Similarity=0.097  Sum_probs=71.5  Template_Neff=11.900

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+..++  . +.++.++..++.+|..+....+.        .+....+++.|...+.+.++.++..++.+|..+...
T Consensus       149 ~~~~l~~~l~~~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  219 (398)
T 4NEE_B          149 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  219 (398)
T ss_pred             HHHHHHHHHcCC-CCCHHHHHHHHHHHHHHHHHChh--------HhcHhhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            455666777  6 46778888999999988764221        111245677788888777888999999999988865


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTG-------NTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~-------~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      ... .......+++.+..++.+...       ....++.++..++.+|..+...
T Consensus       220 ~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~a~~~l~~~~~~  273 (398)
T 4NEE_B          220 NPEEFKTSVSLAVSRLSRIVTSASTDLQDYTYYFVPAPWLSVKLLRLLQCYPPP  273 (398)
T ss_pred             CHHHhHHHHHHHHHHHHHHHcCCCCCCccccccCCCCHHHHHHHHHHHHhhccC
Confidence            211 111112345555555543000       0001456777888888887754


No 419
>3DAD_A FH1/FH2 domain-containing protein 1; Formin, FHOD1, GTPase-binding domain, ubiquitin-superfold; 2.3A {Homo sapiens}
Probab=78.49  E-value=0.18  Score=50.49  Aligned_cols=154  Identities=13%  Similarity=0.081  Sum_probs=94.1  Template_Neff=8.200

Q NP_000290.2     565 LEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVM-GNQVFPEVTR  642 (747)
Q Consensus       565 r~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll-~~giI~~Ll~  642 (747)
                      ...++..|..++.....     ....|++.+++..|+.++...+......++.+|..|...... ..++ ....+..|..
T Consensus       135 l~~~L~~L~~~l~~d~~-----wv~eFi~~~Gl~~L~~~l~~~~~~~~~~~L~cl~~Lm~~~~G~~~v~~~~~~i~~l~~  209 (339)
T 3DAD_A          135 LRRSLFSLKQIFQEDKD-----LVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYT  209 (339)
T ss_dssp             HHHHHHHHHHHHHTCTT-----HHHHHHHTTHHHHHHHHHTTSCHHHHHHHHHHHHHHTTSHHHHHHHHHCHHHHHHHHH
T ss_pred             HHHHHHHHHHHHhCCcc-----HHHHHHHCCHHHHHHHHHHHccHHHHHHHHHHHHHHHhCHHHHHHHHhCHHHHHHHHH
Confidence            34566666666521121     345557788999999999876666777888888888776222 2222 2346677777


Q NP_000290.2     643 LLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFS----------SSMLNNIINLCRSS--ASPKAAEAARLLLSD  710 (747)
Q Consensus       643 LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve----------~giL~~Ll~LL~s~--~d~eVr~aAL~aLsn  710 (747)
                      .+.+      ....++..++.+|..++...+.....+.+          ...+..++..+...  .+.+++..++.++..
T Consensus       210 ~l~s------~~~~v~~~al~iL~~l~~~~~~g~~~Vl~al~~~~~~~~~~~f~~lv~~L~~~~~~d~e~~~~~L~LINa  283 (339)
T 3DAD_A          210 LCAS------LSRLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINK  283 (339)
T ss_dssp             GGGC------SCHHHHHHHHHHHHHHHHHCGGGHHHHHHHHHHHHHHHCCCTTHHHHHHHTTTTSCCHHHHHHHHHHHHH
T ss_pred             HhcC------CCHHHHHHHHHHHHHHHhcCCCcHHHHHHHHHhHHHhhCCCCHHHHHHHHHhhCCCCHHHHHHHHHHHHH
Confidence            7765      35678888888888887654333222222          23466677777642  156677777777777


Q NP_000290.2     711 MWSSKE-------LQGVLRQQGFDRN  729 (747)
Q Consensus       711 L~~~~~-------~~~~~~~~~~~~~  729 (747)
                      |+....       +..-|.+.|+..-
T Consensus       284 Ll~~~~d~~~R~~lr~~L~~~Gi~~i  309 (339)
T 3DAD_A          284 TLAALPDQDSFYDVTDALEQQGMEAL  309 (339)
T ss_dssp             HHHHCSSHHHHHHHHHHHHHTTHHHH
T ss_pred             HHHcCCCHHHHHHHHHHHHHCChHHH
Confidence            664433       3344555665443


No 420
>5VJC_A Protein mini spindles; TOG, HEAT Repeat, Tubulin, CELL; 2.0A {Drosophila melanogaster}
Probab=78.36  E-value=0.16  Score=46.47  Aligned_cols=73  Identities=11%  Similarity=0.004  Sum_probs=44.8  Template_Neff=11.400

Q NP_000290.2     546 SDAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ....+.+...+. +.++.++..++..|..++.....     ..... -..++..+...+.+.++.++..++.++..++..
T Consensus        49 ~~~~~~l~~~l~-~~~~~~r~~a~~~L~~~~~~~~~-----~~~~~-~~~l~~~l~~~l~d~~~~v~~~a~~~l~~l~~~  121 (271)
T 5VJC_A           49 ANVNKALIANMF-HDDFRYHLKVIEQLSEDLAGNSK-----ALVCN-LDLILKWLTLRFYDTNPSVLIKGLEYLVQVFQV  121 (271)
T ss_dssp             TTCCHHHHHHHT-CSSHHHHHHHHHHHHHHTTTCHH-----HHHHT-HHHHHHHHHHHTSSCCHHHHHHHHHHHHHHHHH
T ss_pred             hcCCHHHHHhcc-CCCHHHHHHHHHHHHHHHhcChH-----HHHHH-HHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHH
Confidence            334566777776 46778888888888888764321     01111 123344444555566777888888888877654


No 421
>5WBJ_A Regulatory-associated protein of TOR 1,Eukaryotic; Raptor, TOS, PROTEIN BINDING; 3.0A {Arabidopsis thaliana}
Probab=78.29  E-value=0.18  Score=59.27  Aligned_cols=156  Identities=10%  Similarity=0.095  Sum_probs=112.5  Template_Neff=8.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+++.|.+   +..+..|+..|..++.....     ....+...++++.++.+|.+..++++..++.++++++.. +
T Consensus       467 qLp~~lq~L~s---~~~r~rAL~~L~~~ld~~~~-----~~~~~~~~gi~p~ll~lL~s~~~~lr~~a~~i~a~i~~~d~  538 (1287)
T 5WBJ_A          467 QLPIVLQVLLS---QCHRFRALVLLGRFLDMGSW-----AVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDK  538 (1287)
T ss_dssp             CHHHHHHHTTS---STTHHHHHHHHHHHHTTCHH-----HHHHHHHHTCHHHHHHGGGCCCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHHcC---HHHHHHHHHHHHHHHhcCHH-----HHHHHHHCCcHHHHHHHHcCCCHHHHHHHHHHHHHHHccCH
Confidence            46666777752   23677899999998874332     234445679999999999988889999999999999876 3


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-------SSASP  698 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-------s~~d~  698 (747)
                      .. ..++..+.+..|+.+|....    ..+.++..++.+|+.++...+.....+...+++..+...+.       +. ++
T Consensus       539 ~~q~~l~~~~~l~~ll~~L~~~~----~~~~~r~~a~~~Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~-~~  613 (1287)
T 5WBJ_A          539 SCQIDLVKDGGHTYFIRFLDSSG----AFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQP-EP  613 (1287)
T ss_dssp             GGHHHHHHTTCHHHHHHHHHCSS----CCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHCC----------CH
T ss_pred             HHHHHHHHcCCeeeEEEeecCCC----CCHHHHHHHHHHHHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCC-CH
Confidence            33 34455667888888886420    23556778899999998765555555555577788877776       34 67


Q NP_000290.2     699 KAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       699 eVr~aAL~aLsnL~~~~~  716 (747)
                      .++..++.+|..|+...+
T Consensus       614 ~lr~~a~~~L~~L~~~~~  631 (1287)
T 5WBJ_A          614 LFLQWLCLCLGKLWEDFM  631 (1287)
T ss_dssp             HHHHHHHHHHHHHHTTCH
T ss_pred             HHHHHHHHHHHHHHhccH
Confidence            889999999999986654


No 422
>5WBK_A Regulatory-associated protein of TOR 1,Ribosomal; Raptor, TOS, PROTEIN BINDING; 3.11A {Arabidopsis thaliana}
Probab=78.26  E-value=0.18  Score=59.26  Aligned_cols=156  Identities=10%  Similarity=0.095  Sum_probs=112.8  Template_Neff=8.700

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+++.|.+   +..+..|+..|..++.....     ....+...++++.|+.+|.+..++++..++.++++++.. +
T Consensus       467 ~Lp~~lq~L~s---~~~r~rAL~~L~~~ld~~~~-----a~~~~l~~Gi~p~ll~lL~s~~~~lr~~a~~i~a~i~~~d~  538 (1287)
T 5WBK_A          467 QLPIVLQVLLS---QCHRFRALVLLGRFLDMGSW-----AVDLALSVGIFPYVLKLLQTTTNELRQILVFIWTKILALDK  538 (1287)
T ss_dssp             SHHHHHHHHTS---GGGHHHHHHHHHHHHTTCHH-----HHHHHHHHTCHHHHHHGGGCCCHHHHHHHHHHHHHHHHHCG
T ss_pred             HHHHHHHHHcC---HHHHHHHHHHHHHHHhcCHH-----HHHHHHHCCcHHHHHHHHcCCCHHHHHHHHHHHHHHHccCH
Confidence            46666777752   23677899999998874332     233445679999999999988889999999999999876 3


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCR-------SSASP  698 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~-------s~~d~  698 (747)
                      .. ..++..+.+..|+.+|....    ..+.++..++.+|+.++...+.....+.+.+++..+...|.       +. ++
T Consensus       539 ~~q~~l~~~~~l~~ll~~L~~~~----~~~~~r~~a~~~Ls~l~~~~~~~~~~~~~~~~l~~l~~~L~~~~~~~~~~-~~  613 (1287)
T 5WBK_A          539 SCQIDLVKDGGHTYFIRFLDSSG----AFPEQRAMAAFVLAVIVDGHRRGQEACLEANLIGVCLGHLEASRPSDPQP-EP  613 (1287)
T ss_dssp             GGHHHHHHTTTHHHHHHHHHSSC----CCHHHHHHHHHHHHHHHTTCHHHHHHHHHTTHHHHHHHHCC----------CH
T ss_pred             HHHHHHHHcCCeeeEEEeecCCC----CCHHHHHHHHHHHHHHHcCCHhHHHHHHHCcHHHHHHHHHHhcCCCCCCC-CH
Confidence            33 34455667788888886420    23556778889999998765555555555577888877776       34 68


Q NP_000290.2     699 KAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       699 eVr~aAL~aLsnL~~~~~  716 (747)
                      .++..++.+|..|+....
T Consensus       614 ~lr~~a~~~L~~L~~~~~  631 (1287)
T 5WBK_A          614 LFLQWLCLCLGKLWEDFM  631 (1287)
T ss_dssp             HHHHHHHHHHHHHHTTCH
T ss_pred             HHHHHHHHHHHHHHcccH
Confidence            889999999999986654


No 423
>6EN4_C Splicing factor 3B subunit 3; Protein complex, splicing modulator, SPLICING; HET: BGZ; 3.08A {Homo sapiens}
Probab=78.21  E-value=0.15  Score=53.32  Aligned_cols=154  Identities=10%  Similarity=0.027  Sum_probs=92.8  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.+...+.+ .+ +.++..++.+|..+....+.     .... .-..+++.+...+.+.++.++..++.++..+....
T Consensus       192 ~~~~l~~~l~~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~i~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~  264 (852)
T 6EN4_C          192 LLPFLKAVCKS-KKSWQARHTGIKIVQQIAILMGC-----AILP-HLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAA  264 (852)
T ss_pred             HHHHHHHHHcC-CCCHHHHHHHHHHHHHHHhhCch-----hhcc-cHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHcC
Confidence            34445555552 33 67888888888888754321     1111 12345677777777778889999999998887652


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+      ....++..++.+|..++...+..........+++.+...+.+. ++.++..++
T Consensus       265 ~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~vr~~a~  337 (852)
T 6EN4_C          265 TPYGIESFDSVLKPLWKGIRQ------HRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP-DEEMKKIVL  337 (852)
T ss_pred             CHHHHHHHHHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHhcCCHHHhHHHHHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            11 111112345666666654      2456777888888887764222111111124566666666655 677888888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .++..++...
T Consensus       338 ~~l~~l~~~~  347 (852)
T 6EN4_C          338 KVVKQCCGTD  347 (852)
T ss_pred             HHHHHHhhcC
Confidence            8888877543


No 424
>5F0O_A cohesin subunit Pds5, KLTH0D07062p, KLTH0G16610p; heat repeat cohesin subunit, cell; 3.5A {Lachancea thermotolerans}
Probab=78.20  E-value=0.18  Score=58.49  Aligned_cols=150  Identities=8%  Similarity=0.096  Sum_probs=99.5  Template_Neff=8.400

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .+++.|...|. +.++.+|..|+.+|+.+......  .. ....  ....++.++..+.+.++.++..++.++..+....
T Consensus       280 ~vlp~L~~~L~-~~d~~vR~~Av~~Lg~l~~~~~~--~~-l~~~--~~~l~~~ll~rl~D~~~~VR~~av~~l~~i~~~~  353 (1133)
T 5F0O_A          280 SVTGLLYQLLC-SDNELFRESATKCVSKMLGTHSL--IN-FAVA--HSDTYKIWLSKMADISPHVRQAWVSEIPSILMSR  353 (1133)
T ss_dssp             TSTTTTTTTTS-CSSHHHHHHHHHHHHHHHHSCCS--ST-TTTT--THHHHHHHHHTTSCSCHHHHHHHTTSHHHHHTTC
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHccccc--cc-HHHH--cHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHhcC
Confidence            35677778887 47788899999999998653210  00 0111  1345666777778888999999999998887641


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                      ..   ....+++.|...+.+      .++.++..++.+|+.+.....  .........++.|...+.+. ++.+|..|+.
T Consensus       354 ~~---l~~~ii~~L~~~L~D------~d~~VR~~av~~L~~l~~~~~--~~~~~~~~ll~~L~~~l~D~-~~~VR~~A~~  421 (1133)
T 5F0O_A          354 SD---LSDDISKGLAKALID------SDHTVRLSAIQTFHEVPVKRL--WECLPNAAVFAGLVHLTRET-RRDLRDECID  421 (1133)
T ss_dssp             ST---THHHHHHHHHHTTSC------SSHHHHHHHHTHHHHSCHHHH--HHHCCCHHHHHHHHHGGGBS-SHHHHHHHHH
T ss_pred             hh---HHHHHHHHHHHHhCC------CCHHHHHHHHHHHhhcchhcH--hhcCCchHHHHHHHHHHhcC-CHHHHHHHHH
Confidence            11   112355666666766      478899999999988764311  01111134567777777766 7888999999


Q NP_000290.2     707 LLSDMWSS  714 (747)
Q Consensus       707 aLsnL~~~  714 (747)
                      +|+.+...
T Consensus       422 aL~~l~~~  429 (1133)
T 5F0O_A          422 AVARIYTE  429 (1133)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            88887754


No 425
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=77.79  E-value=0.16  Score=49.54  Aligned_cols=109  Identities=15%  Similarity=0.189  Sum_probs=67.0  Template_Neff=13.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      ..++.+...+. +.++.++..++.++..+......       .. ....+++.+...+.+.++.++..++.++..+... 
T Consensus       236 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~~~~~~~~-------~~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~~~~~~  306 (582)
T 2NYL_A          236 LVMPTLRQAAE-DKSWRVRYMVADKFTELQKAVGP-------EI-TKTDLVPAFQNLMKDCEAEVRAAASHKVKEFCENL  306 (582)
T ss_dssp             TTHHHHHHHHH-CSSHHHHHHHHHTHHHHHHHHCS-------HH-CCCCCHHHHHHHHTCSSHHHHHHHHTTHHHHHHTS
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHhHHHHHHHHCC-------CC-CHhhhHHHHHHHhcCChHHHHHHHHHHHHHHHHhC
Confidence            35566666676 46777888888888887754221       11 1245667777777777788888999998888764 


Q NP_000290.2     626 PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      ... . ......+++.+...+.+      .++.++..++.++..+..
T Consensus       307 ~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~~~~~l~~l~~  347 (582)
T 2NYL_A          307 SADCRENVIMSQILPCIKELVSD------ANQHVKSALASVIMGLSP  347 (582)
T ss_dssp             CTTTHHHHCCCCCHHHHHHHHTC------SCHHHHHHHHHHGGGGHH
T ss_pred             CCcchHHHHHHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHH
Confidence            111 1 11112345555555554      245666667777666654


No 426
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=77.60  E-value=0.16  Score=54.65  Aligned_cols=157  Identities=9%  Similarity=0.079  Sum_probs=90.3  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.+...+. +.++.++..++.+|..++...+.     .... ....+++.|...+.+.++.++..++.+|+.++.. +
T Consensus       849 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  921 (1078)
T 3W3W_A          849 IWPMINTFLL-DNEPILVIFALVVIGDLIQYGGE-----QTAS-MKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAP  921 (1078)
T ss_dssp             GHHHHHHHHC---CHHHHHHHHHHHHHHHTC--C-----CCHH-HHHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHSS
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcch-----hhHH-HHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHCc
Confidence            3445555555 35667777888888888764221     1111 1245677778888888889999999999999876 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.+...+.........+..++..++.+|..+....+....  ....+++.++..+....+..++..++
T Consensus       922 ~~~~~~~-~~~l~~l~~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~~~~~~~~~~~  998 (1078)
T 3W3W_A          922 STYADVC-IPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIP--NVDTYTANWFKTLPTITDKEAASFNY  998 (1078)
T ss_dssp             TTTHHHH-HHHHHHHHHHTC--CCSSGGGHHHHHHHHHHHHHHHHHTTTSCC----CHHHHHHHTTCCCCSCHHHHHHHH
T ss_pred             cchHhhH-HHHHHHHHHHHhCCCCcchhchhhHHHHHHHHHHHHHHcccCCC--chhHHHHHHHHhCCccCCHHHHHHHH
Confidence            21 1112 34666677766521000003567888899999988765332111  12235566666664222567788888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       999 ~~l~~l~~~ 1007 (1078)
T 3W3W_A          999 QFLSQLIEN 1007 (1078)
T ss_dssp             HHHHC----
T ss_pred             HHHHHHHHc
Confidence            888777654


No 427
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=77.52  E-value=0.17  Score=44.16  Aligned_cols=115  Identities=13%  Similarity=-0.025  Sum_probs=73.8  Template_Neff=12.800

Q NP_000290.2     239 DIECSGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRS  318 (747)
Q Consensus       239 ~~~~~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~  318 (747)
                      ........++.+...+.+.++.++..++..+..+.......   .....+++.+...+.+.++.++..++.++..+....
T Consensus        27 ~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~---~~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~~~~~~  103 (258)
T 4LAC_A           27 CESMSLYPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVE---RTRSELLPFIVELAEDAKWRVRLAIIEYMPLLAGQL  103 (258)
T ss_pred             CCCccccHHHHHHHHhcCCCHHHHHHHHHHHHHHHHccCHH---HHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHhC
Confidence            33334456666777777777888888888888877543211   112345566666676777788888888888776543


Q NP_000290.2     319 TTNKLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       319 ~~~~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ..   ......+++.+...+. +.++.++..++.++..+...
T Consensus       104 ~~---~~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~  141 (258)
T 4LAC_A          104 GV---EYFDEKLNSLCMAWLV-DHVYAIREAATSNLKKLVEK  141 (258)
T ss_pred             CC---hHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHc
Confidence            22   1112245556666665 55677888888888887754


No 428
>6FT5_A A3_A3; alphaRep, artificial protein, chimera, bidomain; HET: GOL, SO4; 1.94A {synthetic construct}
Probab=77.46  E-value=0.17  Score=47.66  Aligned_cols=60  Identities=17%  Similarity=0.244  Sum_probs=30.0  Template_Neff=12.800

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.+...+. +.++.++..++.+|..+...                ..++.+...+.+.++.++..++.++..+.
T Consensus        54 ~~~~~l~~~l~-~~~~~vr~~a~~~L~~~~~~----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~  113 (409)
T 6FT5_A           54 RAVEPLIKALK-DEDAWVRRAAADALGQIGDE----------------RAVEPLIKALKDEDGWVRQSAAVALGQIG  113 (409)
T ss_pred             chHHHHHHHhc-CCCHHHHHHHHHHHHHHcCc----------------hhHHHHHHHhcCCCHHHHHHHHHHHHhhC
Confidence            34455555555 34555555666655554321                12233444444555556666666555544


No 429
>1F59_B IMPORTIN BETA-1/FXFG NUCLEOPORIN; Protein-protein complex, TRANSPORT PROTEIN RECEPTOR; 2.8A {Homo sapiens} SCOP: a.118.1.1
Probab=77.42  E-value=0.17  Score=48.11  Aligned_cols=158  Identities=12%  Similarity=0.047  Sum_probs=88.7  Template_Neff=12.900

Q NP_000290.2     547 DAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSS-------GMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       547 G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~-------~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      +.+..++.++.+. .++.++..|+.+|.++...... ..       ......-....+++.|+..+.+.... +..++.+
T Consensus        35 ~~~~~l~~~l~~~~~~~~~r~~a~~~l~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~l~~~l~~~l~~~~~~-r~~~~~~  112 (442)
T 1F59_B           35 TFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDP-DIKAQYQQRWLAIDANARREVKNYVLHTLGTETYR-PSSASQC  112 (442)
T ss_dssp             HHHHHHHHHTTCTTSCHHHHHHHHHHHHTTTCCSSH-HHHHHHHHHHHTSCHHHHHHHHHHHHHHTTCCSSS-SCHHHHH
T ss_pred             HHHHHHHHHHhCCCCCHHHHHHHHHHHHHHhhcCCH-HHHHHHHHHHhhCCHHHHHHHHHHHHHHHCCCCCc-hhHHHHH
Confidence            4556667776521 3566777788888887643110 00       00000001234555566666544333 7778888


Q NP_000290.2     619 LSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS--EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d--~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      ++.++...... .....+++.+...+.+      .+  +.++..++.+|..+...............+++.+..++.+. 
T Consensus       113 l~~l~~~~~~~-~~~~~~~~~l~~~l~~------~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  184 (442)
T 1F59_B          113 VAGIACAEIPV-NQWPELIPQLVANVTN------PNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKE-  184 (442)
T ss_dssp             HHHHHHHHGGG-TCCTTHHHHHHHHHHC------TTCCHHHHHHHHHHHHHHHHHSCGGGGGGGHHHHHHHHHHTTSTT-
T ss_pred             HHHHHHhcCCc-chhchHHHHHHHHhhC------CCCcHHHHHHHHHHHHHHHhhCCHHHhHHHHHHHHHHHHHHHhcC-
Confidence            88777541110 0112356666666665      23  67888888998888764221111111124566777777655 


Q NP_000290.2     697 S--PKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d--~eVr~aAL~aLsnL~~~  714 (747)
                      +  ..++..++.++..++..
T Consensus       185 ~~~~~vr~~a~~~l~~l~~~  204 (442)
T 1F59_B          185 EPSNNVKLAATNALLNSLEF  204 (442)
T ss_dssp             CCCHHHHHHHHHHHHHHSTT
T ss_pred             CCCHHHHHHHHHHHHHHHHH
Confidence            4  78889999988888654


No 430
>2NYL_A Protein phosphatase 2, regulatory subunit; HEAT repeat, HYDROLASE-HYDROLASE INHIBITOR COMPLEX; HET: DAL, MSE, ACB, 1ZN, DAM, FGA; 3.8A {Homo sapiens} SCOP: a.118.1.2
Probab=77.33  E-value=0.16  Score=49.36  Aligned_cols=70  Identities=17%  Similarity=0.113  Sum_probs=41.5  Template_Neff=13.500

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ..++.+...+. +.++.++..++.++..+......      . . .....++.+...+.+.++.++..++.++..+...
T Consensus       318 ~~~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~------~-~-~~~~~~~~l~~~l~~~~~~v~~~a~~~l~~l~~~  387 (582)
T 2NYL_A          318 QILPCIKELVS-DANQHVKSALASVIMGLSPILGK------D-N-TIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEV  387 (582)
T ss_dssp             CCHHHHHHHHT-CSCHHHHHHHHHHGGGGHHHHHH------H-H-CCCCCHHHHHHHHHCSSHHHHHHHHTTHHHHTTT
T ss_pred             HHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCC------c-c-chhhHHHHHHHHhcCCCHHHHHHHHHhHHHHHHh
Confidence            34556666666 35666777777777776653211      1 1 1134556666666666667777777777766643


No 431
>5FVM_B SERINE/THREONINE-PROTEIN KINASE TOR2, TARGET OF; TRANSFERASE, CRYO-EM, TOR, LST8, MTOR; 6.7A {KLUYVEROMYCES MARXIANUS}
Probab=77.24  E-value=0.18  Score=61.64  Aligned_cols=71  Identities=11%  Similarity=0.111  Sum_probs=39.6  Template_Neff=11.500

Q NP_000290.2     548 AIRTYLNLMGKSKKD-ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~-eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++..+..++.. ... .++..++.++..++.....     ....+ -..+++.+...+.+.++.++..++.+|..++..
T Consensus       925 ~~~~l~~~l~~-~~~~~~~~~~~~~l~~i~~~~~~-----~~~~~-l~~l~~~l~~~l~~~~~~vr~~a~~~L~~l~~~  996 (2471)
T 5FVM_B          925 VIGVLMKILKD-PSLSIHHSTVIQAIMHIFQTMGL-----RCVIF-LKQIIPGFILVMHTCPPSLLELYFQQLSVLISI  996 (2471)
T ss_dssp             HHHHHHHHHHC----CCHHHHHHHHHHHHHHHC-----------C-HHHHHHHHHHHHC--CHHHHHHHHHHHHHHTTS
T ss_pred             HHHHHHHHHcC-ccchHHHHHHHHHHHHHHHHccc-----hhHHH-HhHHHHHHHHHHhhCCHHHHHHHHHHHHHHHHH
Confidence            34556666652 322 2666777788777653221     01111 134566677777766778888888888888764


No 432
>3LTJ_A AlphaRep-4; protein engineering, HEAT-like repeat, PROTEIN; 1.8A {synthetic}
Probab=77.21  E-value=0.18  Score=42.73  Aligned_cols=121  Identities=12%  Similarity=0.121  Sum_probs=68.3  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+...                ..++.+...+.+.++.++..++.++..+...  
T Consensus        77 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--  137 (201)
T 3LTJ_A           77 AVEPLIKALK-DEDGWVRQSAAVALGQIGDE----------------RAVEPLIKALKDEDWFVRIAAAFALGEIGDE--  137 (201)
T ss_dssp             GHHHHHHHTT-CSSHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHTCG--
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHhCCH----------------HHHHHHHHHHhCCCHHHHHHHHHHHHHHCCH--
Confidence            3445555565 35566666666666655421                1233444555566667777777776665431  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.++..+...           .....+..++.+. ++.++..++.+
T Consensus       138 -------~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~-----------~~~~~l~~~~~~~-~~~vr~~a~~~  192 (201)
T 3LTJ_A          138 -------RAVEPLIKALKD------EDGWVRQSAADALGEIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  192 (201)
T ss_dssp             -------GGHHHHHHHTTC------SSHHHHHHHHHHHHHHCSH-----------HHHHHHHHHHHHC-CHHHHHHHHHH
T ss_pred             -------HHHHHHHHHHhC------CChHHHHHHHHHHHHhCcH-----------HHHHHHHHHHHcC-CHHHHHHHHHH
Confidence                   133444455544      2456677777777665431           2334455555555 67778888877


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      |.++.
T Consensus       193 l~~~~  197 (201)
T 3LTJ_A          193 LETHK  197 (201)
T ss_dssp             HHHCC
T ss_pred             HHhhh
Confidence            77654


No 433
>5JO8_A CEP104; centriolar protein, TOG domain, CEP104; 1.4A {Gallus gallus}
Probab=77.19  E-value=0.18  Score=46.55  Aligned_cols=155  Identities=14%  Similarity=0.100  Sum_probs=90.5  Template_Neff=11.100

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLM---SSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~---s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      .++.+...+. +.++.++..++.++..++......   ... .... .-..+++.|+..+.+.+..++..+..+|..++.
T Consensus        87 l~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~-~~~~~l~~ll~~l~d~~~~vr~~a~~~l~~l~~  163 (279)
T 5JO8_A           87 AIFLVRRAIK-DIVSSVFQASLKLLKMIITQYVPKHKLGKL-ETSH-CVEKTLPGLLSRTGDSSSRLRIVAAKFIQEMAL  163 (279)
T ss_dssp             HHHHHHHHTT-CSSHHHHHHHHHHHHHCCCCCHHHHTCCHH-HHHH-HHHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHcC-CCHHHHHHHHHHHHHHHHHHhcccccCChH-HHHH-HHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHc
Confidence            3445555666 466778888888888877542000   000 0111 113466777777777778888999999888875


Q NP_000290.2     625 HPLLHRVMGNQVFP-EVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       625 ~~e~~~ll~~giI~-~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      .....   ...++. .+...+...     .++.++..++.+|..++..............+++.+...+.+. ++.++..
T Consensus       164 ~~~~~---~~~~~~~~l~~~l~~~-----~~~~~r~~~l~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~d~-~~~VR~~  234 (279)
T 5JO8_A          164 WSEVK---PLQIVPVHLVQLLKPN-----SPTHLAMSRVELVECLLKEMGTENSGFTISNVMKFATGALEHR-VYEVRDV  234 (279)
T ss_dssp             STTTG---GGCCHHHHHTSCCCTT-----SCHHHHHHHHHHHHHHHHHHCSSSSSCCHHHHHHHHHHHTTCS-CHHHHHH
T ss_pred             CCCCC---hhHhHHHHHhhcCCCC-----CCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHhcCC-CHHHHHH
Confidence            42110   011222 222333331     1566777888888887764322211111224567777777766 8899999


Q NP_000290.2     704 ARLLLSDMWSS  714 (747)
Q Consensus       704 AL~aLsnL~~~  714 (747)
                      +..++..+...
T Consensus       235 a~~~l~~l~~~  245 (279)
T 5JO8_A          235 ALRIIFGMYRK  245 (279)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHHHH
Confidence            99988887643


No 434
>4P6Z_G BST2/tetherin, HIV-1 Vpu, Clathrin adaptor; BST2, tetherin, Vpu, HIV, clathrin; 3.0A {Mus musculus}
Probab=77.19  E-value=0.18  Score=51.67  Aligned_cols=101  Identities=12%  Similarity=0.040  Sum_probs=52.0  Template_Neff=12.000

Q NP_000290.2     246 TIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLET  325 (747)
Q Consensus       246 iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~l  325 (747)
                      +++.+...+.+.+..++..++..+..+....       ....+++.+...+.+.++.++..++.++..+....+...   
T Consensus       117 ~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~-------~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~~~~~~~~---  186 (627)
T 4P6Z_G          117 MTNCIKNDLNHSTQFVQGLALCTLGCMGSSE-------MCRDLAGEVEKLLKTSNSYLRKKAALCAVHVIRKVPELM---  186 (627)
T ss_dssp             HHHHHHHHHTCSSHHHHHHHHHHHHHHCCHH-------HHHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHCSGGG---
T ss_pred             HHHHHHHHhhCCCHHHHHHHHHHHHhcCCHH-------HHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHHHHCHHHH---
Confidence            3444444444555556666666665554211       011334455555555566666666666666654322111   


Q NP_000290.2     326 RRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       326 l~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas  359 (747)
                        ..+++.+...+. +.++.++..++.++..+..
T Consensus       187 --~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~  217 (627)
T 4P6Z_G          187 --EMFLPATKNLLN-EKNHGVLHTSVVLLTEMCE  217 (627)
T ss_dssp             --GGGHHHHTTCTT-CCCHHHHHHHHHHHHHHHH
T ss_pred             --HHHHHHHHHHHh-CCCHHHHHHHHHHHHHHHH
Confidence              234445555554 4455666666666666654


No 435
>1GCJ_B IMPORTIN-BETA; HEAT REPEAT MOTIF, NUCLEAR PORE-TARGETING; HET: MSE; 2.6A {Mus musculus} SCOP: a.118.1.1
Probab=77.16  E-value=0.17  Score=48.43  Aligned_cols=154  Identities=10%  Similarity=0.066  Sum_probs=84.6  Template_Neff=12.800

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM--------S----SGMSQ----LIGLKEKGLPQIARLLQSG-----  607 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~--------s----~~~~~----~llie~giI~~Ll~LL~s~-----  607 (747)
                      ++.+..++. +.++.++..++.++..++......        .    .....    .. .-..+++.+...+...     
T Consensus       267 ~~~l~~~l~-~~~~~v~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~l~~~l~~~l~~~~~~~~  344 (460)
T 1GCJ_B          267 FAITIEAMK-SDIDEVALQGIEFWSNVCDEEMDLAIEASEAAEQGRPPEHTSKFYAKG-ALQYLVPILTQTLTKQDENDD  344 (460)
T ss_dssp             HHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCSSCCCCHHHH-HHHHHHHHHHHHGGGCCSSSC
T ss_pred             HHHHHHHhh-CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCcchhhhhhHhH-HHHHHHHHHHHHHhcCCCCCC
Confidence            555666666 356777778888888776531000        0    00000    00 0122344444444322     


Q NP_000290.2     608 --NSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQL-AKQYFSSSM  684 (747)
Q Consensus       608 --d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~-~~~Lve~gi  684 (747)
                        +..++..+..++..++..... ..+ ..+++.+...+.+      .++.++..++.+|..+....... ....+ ..+
T Consensus       345 ~~~~~~~~~a~~~l~~l~~~~~~-~~~-~~~~~~l~~~l~~------~~~~~r~~a~~~l~~l~~~~~~~~~~~~~-~~~  415 (460)
T 1GCJ_B          345 DDDWNPCKAAGVCLMLLSTCCED-DIV-PHVLPFIKEHIKN------PDWRYRDAAVMAFGSILEGPEPNQLKPLV-IQA  415 (460)
T ss_dssp             TTSCCHHHHHHHHHHHHHHHHGG-GHH-HHHHHHHHHHTTC------SSHHHHHHHHHHHHHTSSSSCHHHHHHHH-HHH
T ss_pred             CCCCcHHHHHHHHHHHHHhhCcc-ccH-HHHHHHHHHHhcC------CChHHHHHHHHHHHHHHcCCChhhHHHHH-HHH
Confidence              345666677777776654110 111 1234444444444      36778889999999988653321 11111 245


Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.+...+.+. ++.++..++++|..++..
T Consensus       416 ~~~l~~~l~~~-~~~vr~~a~~~l~~l~~~  444 (460)
T 1GCJ_B          416 MPTLIELMKDP-SVVVRDTTAWTVGRICEL  444 (460)
T ss_dssp             HHHHHHHTTCS-CHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhCCC-CHHHHHHHHHHHHHHHHh
Confidence            66667777666 788999999999988754


No 436
>6GWC_C Tubulin alpha chain, Tubulin beta; microtubule, ARTIFICIAL PROTEIN, ALPHAREP, cytoskeleton; HET: GTP, MES, PGE; 2.6A {Ovis aries}
Probab=76.89  E-value=0.18  Score=43.85  Aligned_cols=121  Identities=12%  Similarity=0.169  Sum_probs=73.3  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+..++. +.++.++..++.+|..+...                ..++.+..++.+.++.++..++.++..+...  
T Consensus       108 ~~~~l~~~l~-~~~~~~r~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~--  168 (232)
T 6GWC_C          108 AVEPLIKALK-DEDTTVRRIAATALGKIGDE----------------RAVEPLIKALKDEDAAVRLTAARALGEIGDE--  168 (232)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHhccc----------------chHHHHHHHhcCCCHHHHHHHHHHHHHhCCh--
Confidence            3455666665 35667777777777665431                1233455566666777888888777766431  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+...+.+      .++.++..++.+|..+...           ..+..+..++.+. ++.++..++.+
T Consensus       169 -------~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~~-----------~~~~~l~~~~~~~-~~~v~~~a~~~  223 (232)
T 6GWC_C          169 -------RAVEPLIKALKD------EDAYVRRAAAQALGKIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  223 (232)
T ss_pred             -------hHHHHHHHHhcC------CCHHHHHHHHHHHHHhCcC-----------chHHHHHHHHhCC-CHHHHHHHHHH
Confidence                   234445555554      2567777788887776542           2344455555554 66777778777


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      |..+.
T Consensus       224 l~~~~  228 (232)
T 6GWC_C          224 LETHK  228 (232)
T ss_pred             HHHHH
Confidence            77654


No 437
>3QML_D 78 kDa glucose-regulated protein homolog; Armadillo like repeats, CHAPERONE-PROTEIN TRANSPORT; HET: PO4; 2.31A {Saccharomyces cerevisiae}
Probab=76.82  E-value=0.22  Score=49.40  Aligned_cols=104  Identities=8%  Similarity=0.064  Sum_probs=73.8  Template_Neff=7.900

Q NP_000290.2     609 SDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSS--ML  685 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~g--iL  685 (747)
                      ...+..++.-|..++..-++ ..+...+ +..|+.++...    .....++..|+++|+..+.+++.....+.+.+  ++
T Consensus        42 ~~~~~~aLd~L~dl~hdid~a~~~~~~g-~~~L~~~l~~~----~~~~~ir~~Aa~iigsa~qNNP~aq~~~~~~~~~~l  116 (315)
T 3QML_D           42 IARLEDSFDRIMEFAHDYKHGYKIITHE-FALLANLSLNE----NLPLTLRELSTRVITSCLRNNPPVVEFINESFPNFK  116 (315)
T ss_dssp             HHHHHHHHHHHHHHHTSHHHHHHHHHHH-HHHHHHHHHCT----TSCHHHHHHHHHHHHHHHTTCTTHHHHHHHHCTTHH
T ss_pred             HHHHHHHHHHHHHHHccHHHHHHHHHch-HHHHHHHHhCC----CCCHHHHHHHHHHHHHHHhhCHHHHHHHHHHCccHH
Confidence            34455566666666655333 3455566 77777776541    02578999999999999999988888888766  67


Q NP_000290.2     686 NNII---NLCRS---SASPKAAEAARLLLSDMWSSKEL  717 (747)
Q Consensus       686 ~~Ll---~LL~s---~~d~eVr~aAL~aLsnL~~~~~~  717 (747)
                      +.|+   ..+..   ..++.++..++.+|+.++.+.+.
T Consensus       117 ~~Ll~~~~~L~~~~~~~~~~v~~k~L~aLS~Lir~~~~  154 (315)
T 3QML_D          117 SKIMAALSNLNDSNHRSSNILIKRYLSILNELPVTSED  154 (315)
T ss_dssp             HHHHHHHHHHHCC---CTHHHHHHHHHHHHHSCCCGGG
T ss_pred             HHHHHHHHhhccCCCcCCHHHHHHHHHHHHhhcCCCcc
Confidence            7777   44443   22678889999999999988765


No 438
>4G3A_B CLIP-associating protein; TOG domain, HEAT repeat, MAP; HET: GOL; 1.994A {Drosophila melanogaster}
Probab=76.80  E-value=0.18  Score=43.50  Aligned_cols=113  Identities=13%  Similarity=0.037  Sum_probs=64.2  Template_Neff=12.600

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.+...+.+.++.++..++..+..++..............+++.+...+.+.++.++..++.++..++........
T Consensus         6 ~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~d~~~~v~~~a~~~l~~l~~~~~~~~~   85 (237)
T 4G3A_B            6 PSDLDGFIQQMPKADMRVKVQLAEDLVTFLSDDTNSIVCTDMGFLIDGLMPWLTGSHFKIAQKSLEAFSELIKRLGSDFN   85 (237)
T ss_dssp             CSSHHHHHHHSTTCCHHHHHHHHHHHHHHHHCTTSCCCCSCHHHHHHHHGGGGSSSCHHHHHHHHHHHHHHHHHHGGGGG
T ss_pred             cchHHHHHHhcCcCCHHHHHHHHHHHHHHhhCCCCCcccccHHHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHhhhhHH
Confidence            34455566666677778888888888887764321111111123556666667667778888888888887754332111


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .. ...+++.+...+. +.+..++..++.++..+.
T Consensus        86 ~~-~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  118 (237)
T 4G3A_B           86 AY-TATVLPHVIDRLG-DSRDTVREKAQLLLRDLM  118 (237)
T ss_dssp             GT-HHHHHHHHHHHHT-CSCHHHHHHHHHHHHHHH
T ss_pred             HH-HHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHH
Confidence            11 1234455555554 334445555555555544


No 439
>6IDX_A Engulfment and cell motility protein; Adhesion GPCRs, CELL ADHESION; 1.699A {Homo sapiens}
Probab=76.77  E-value=0.22  Score=52.79  Aligned_cols=157  Identities=13%  Similarity=0.168  Sum_probs=98.0  Template_Neff=8.400

Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG------NSDVVRSGASLLSNMSRHP-LL-HRVMGN  634 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~------d~eVr~~AL~aLsnLa~~~-e~-~~ll~~  634 (747)
                      ..+..++.-|..++.. ..     ....|++.+++..|+.++...      +......++.+|..+.... .. ..+. .
T Consensus       102 ~~~~~~L~~L~~~~~d-~~-----f~~EFi~~~Gl~~L~~~l~~~~~~~~~~~~~l~~~L~al~~lM~~~~~g~~~l~-~  174 (524)
T 6IDX_A          102 ETRLDAMKELAKLSAD-VT-----FATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVS-I  174 (524)
T ss_pred             HHHHHHHHHHHHHhcC-hh-----HHHHHHHcChHHHHHHHHHhCCCCCCCChhHHHHHHHHHHHHHhcCcccHhhch-H
Confidence            3444566666666653 22     345557788999999988863      4466777888888888764 32 2222 3


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ..+..|..++...    ..+..+...++.+|..++...+.....+.....+..|+..|... +..++..++.++..|...
T Consensus       175 ~~i~~l~~~l~~~----~~~~~v~~~aL~iL~~l~~~~~~~~~~v~~~~~f~~Lv~~L~~~-d~~~q~~~L~LINaLl~~  249 (524)
T 6IDX_A          175 TFIKQIAGYVSQP----MVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVS-NQEIQTYAIALINALFLK  249 (524)
T ss_pred             HHHHHHHHHhCCC----CCChhHHHHHHHHHHHHHhcCHHHHHHHHcCCCHHHHHHHHccC-CHHHHHHHHHHHHHHHhc
Confidence            4667777777542    00237888899999888775433333222222377788888765 677778887777777654


Q NP_000290.2     715 K------ELQGVLRQQGFDRNML  731 (747)
Q Consensus       715 ~------~~~~~~~~~~~~~~~~  731 (747)
                      .      ++..-|...|+..-..
T Consensus       250 ~~~~~~~~i~~~L~~~gi~~~i~  272 (524)
T 6IDX_A          250 APEDKRQDMANAFAQKHLRSIIL  272 (524)
T ss_pred             CCcccHHHHHHHHHHcCHHHHHH
Confidence            4      3444555666655433


No 440
>6IE1_A Engulfment and cell motility protein; Adhesion GPCR, BAI1-ELMO2 Complex, cell; HET: GOL; 2.48A {Homo sapiens}
Probab=76.77  E-value=0.22  Score=52.79  Aligned_cols=157  Identities=13%  Similarity=0.168  Sum_probs=98.0  Template_Neff=8.400

Q NP_000290.2     563 ATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSG------NSDVVRSGASLLSNMSRHP-LL-HRVMGN  634 (747)
Q Consensus       563 eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~------d~eVr~~AL~aLsnLa~~~-e~-~~ll~~  634 (747)
                      ..+..++.-|..++.. ..     ....|++.+++..|+.++...      +......++.+|..+.... .. ..+. .
T Consensus       102 ~~~~~~L~~L~~~~~d-~~-----f~~EFi~~~Gl~~L~~~l~~~~~~~~~~~~~l~~~L~al~~lM~~~~~g~~~l~-~  174 (524)
T 6IE1_A          102 ETRLDAMKELAKLSAD-VT-----FATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVS-I  174 (524)
T ss_pred             HHHHHHHHHHHHHhcC-hh-----HHHHHHHcChHHHHHHHHHhCCCCCCCChhHHHHHHHHHHHHHhcCcccHhhch-H
Confidence            3444566666666653 22     345557788999999988863      4466777888888888764 32 2222 3


Q NP_000290.2     635 QVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       635 giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ..+..|..++...    ..+..+...++.+|..++...+.....+.....+..|+..|... +..++..++.++..|...
T Consensus       175 ~~i~~l~~~l~~~----~~~~~v~~~aL~iL~~l~~~~~~~~~~v~~~~~f~~Lv~~L~~~-d~~~q~~~L~LINaLl~~  249 (524)
T 6IE1_A          175 TFIKQIAGYVSQP----MVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVS-NQEIQTYAIALINALFLK  249 (524)
T ss_pred             HHHHHHHHHhCCC----CCChhHHHHHHHHHHHHHhcCHHHHHHHHcCCCHHHHHHHHccC-CHHHHHHHHHHHHHHHhc
Confidence            4667777777542    00237888899999888775433333222222377788888765 677778887777777654


Q NP_000290.2     715 K------ELQGVLRQQGFDRNML  731 (747)
Q Consensus       715 ~------~~~~~~~~~~~~~~~~  731 (747)
                      .      ++..-|...|+..-..
T Consensus       250 ~~~~~~~~i~~~L~~~gi~~~i~  272 (524)
T 6IE1_A          250 APEDKRQDMANAFAQKHLRSIIL  272 (524)
T ss_pred             CCcccHHHHHHHHHHcCHHHHHH
Confidence            4      3444555666655433


No 441
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=76.57  E-value=0.18  Score=54.22  Aligned_cols=157  Identities=9%  Similarity=0.079  Sum_probs=92.1  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      +++.+...+. +.++.++..++.++..++.....     .... ....+++.|...+.+.++.++..++.+|+.++.. +
T Consensus       849 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  921 (1078)
T 5H2V_A          849 IWPMINTFLL-DNEPILVIFALVVIGDLIQYGGE-----QTAS-MKNAFIPKVTECLISPDARIRQAASYIIGVCAQYAP  921 (1078)
T ss_dssp             GHHHHHHHHH-SSSHHHHHHHHHHHHHHHHHHTT-----TTTT-THHHHHHHHHHHHTCSCHHHHHHHHHHHHHHHHHCT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHhcch-----hhHH-HHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHCc
Confidence            3445555555 35667777888888887754221     1111 1245677778888888889999999999999876 2


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.+...+.........+..++..++.+|..+....+....  ....+++.++..+....+..++..++
T Consensus       922 ~~~~~~~-~~~l~~l~~~l~~~~~~~~~~~~~~~~a~~~l~~l~~~~~~~~~--~~~~~~~~l~~~l~~~~~~~~~~~~~  998 (1078)
T 5H2V_A          922 STYADVC-IPTLDTLVQIVDFPGSKLEENRSSTENASAAIAKILYAYNSNIP--NVDTYTANWFKTLPTITDKEAASFNY  998 (1078)
T ss_dssp             TTTHHHH-TTTHHHHHHHTC--CCSSTTTHHHHHHHHHHHHHHHHHC---------CHHHHHHHTTCCCCSCHHHHHHHH
T ss_pred             cchHHhH-HHHHHHHHHHHhCCCCccccccchHHHHHHHHHHHHHHcccCCC--ChhHHHHHHHHhCCccCCHHHHHHHH
Confidence            21 1111 34666677766521000003567888899999888764322111  11234556666664222567777888


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..+...
T Consensus       999 ~~l~~l~~~ 1007 (1078)
T 5H2V_A          999 QFLSQLIEN 1007 (1078)
T ss_dssp             HHHHHHHC-
T ss_pred             HHHHHHHHc
Confidence            888777654


No 442
>1TE4_A conserved protein MTH187; MTH187, Methanobacterium thermoautotrophicum, structural proteomics; NMR {Methanothermobacter thermautotrophicus} SCOP: a.118.1.16
Probab=76.51  E-value=0.19  Score=39.52  Aligned_cols=118  Identities=13%  Similarity=0.147  Sum_probs=65.1  Template_Neff=12.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      ..+.+...+. +.++.++..++..|..+..                 ..++.+...+.+.++.++..++.++..+...  
T Consensus        13 ~~~~~~~~l~-~~~~~~r~~a~~~l~~~~~-----------------~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~--   72 (131)
T 1TE4_A           13 GLVPRGSHMA-DENKWVRRDVSTALSRMGD-----------------EAFEPLLESLSNEDWRIRGAAAWIIGNFQDE--   72 (131)
T ss_dssp             --------CC-SSCCCSSSSCCSSTTSCSS-----------------TTHHHHHHGGGCSCHHHHHHHHHHHGGGCSH--
T ss_pred             CccccHHHhc-CCCHHHHHHHHHHHHHhcH-----------------HHHHHHHHHhcCCCHHHHHHHHHHHHcCCCh--
Confidence            3455666666 4666777777766654421                 1234455556666777888888888776532  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.|...+.+      .++.++..++.+|..+...           ..++.+...+.+. +..++..++.+
T Consensus        73 -------~~~~~l~~~l~~------~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a~~~  127 (131)
T 1TE4_A           73 -------RAVEPLIKLLED------DSGFVRSGAARSLEQIGGE-----------RVRAAMEKLAETG-TGFARKVAVNY  127 (131)
T ss_dssp             -------HHHHHHHHHHHH------CCTHHHHHHHHHHHHHCSH-----------HHHHHHHHHTTSC-CTHHHHHHHHH
T ss_pred             -------hhHHHHHHHhcC------CCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHHcCC-CHHHHHHHHHH
Confidence                   133444455544      2567777788888776531           1344455555544 56677766666


Q NP_000290.2     708 LSD  710 (747)
Q Consensus       708 Lsn  710 (747)
                      +..
T Consensus       128 l~~  130 (131)
T 1TE4_A          128 LET  130 (131)
T ss_dssp             GGG
T ss_pred             Hhc
Confidence            543


No 443
>6S47_Bi 60S ribosomal protein L2-A, 60S; New1, ABCF, Ribosomal Protein, Recycling; HET: ATP; 3.28A {Saccharomyces cerevisiae}
Probab=76.45  E-value=0.2  Score=54.82  Aligned_cols=155  Identities=15%  Similarity=0.167  Sum_probs=91.4  Template_Neff=11.700

Q NP_000290.2     548 AIRTYLNLMGKSKK-DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d-~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-  625 (747)
                      +++.|..++.. .+ +.++..++.+|..++.....     .........+++.|+.++.+.++.++..|+.+|..++.. 
T Consensus       127 ~~~~l~~~l~~-~~~~~vr~~a~~~l~~i~~~~~~-----~~~~~~~~~~~~~l~~~l~d~~~~vr~~a~~~L~~l~~~~  200 (972)
T 6S47_Bi         127 VLPTILDYLSS-GAKWQAKMAALSVVDRIREDSAN-----DLLELTFKDAVPVLTDVATDFKPELAKQGYKTLLDYVSIL  200 (972)
T ss_pred             hHHHHHHHcCC-CCCHHHHHHHHHHHHHHHhhCCH-----HHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHh
Confidence            46667777763 44 67888889998888543221     111112345777788888888888899999988888753 


Q NP_000290.2     626 PL-L-H----RV---MG--------------------------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMA  670 (747)
Q Consensus       626 ~e-~-~----~l---l~--------------------------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~  670 (747)
                      .. . .    .+   +.                          ..+++.+...+.+.    ..+..++..++++|..++.
T Consensus       201 ~~~~~~~~~~~l~~~l~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~l~~  276 (972)
T 6S47_Bi         201 DNLDLSPRYKLIVDTLQDPSKVPESVKSLSSVTFVAEVTEPSLSLLVPILNRSLNLS----SSSQEQLRQTVIVVENLTR  276 (972)
T ss_pred             CcHHHHHHHHHHHHHcCChHHHHHHHHHHHHhhCCCCCCcccHHHHHHHHHHHHhCC----CCCHHHHHHHHHHHHHHHH
Confidence            10 0 0    00   00                          00223333333220    0245677788888888875


Q NP_000290.2     671 --SQPQLAKQYFSSSMLNNIINLC-RSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       671 --~s~e~~~~Lve~giL~~Ll~LL-~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                        ........+ ...+++.|+..+ .+. +..++..|+.+|..++..
T Consensus       277 ~~~~~~~~~~~-~~~i~~~L~~~l~~d~-~~~vr~~a~~~l~~l~~~  321 (972)
T 6S47_Bi         277 LVNNRNEIESF-IPLLLPGIQKVVDTAS-LPEVRELAEKALNVLKED  321 (972)
T ss_pred             hcCChhHcHhh-HHHHHHHHHHHHhcCC-CHHHHHHHHHHHHHHhhh
Confidence              211111111 124566777777 555 778899999999998876


No 444
>1OYZ_A X-RAY STRUCTURE OF YB61_HAEIN NORTHEAST; STRUCTURAL GENOMICS, PSI, Protein Structure; 2.1A {Escherichia coli} SCOP: a.118.1.16
Probab=76.37  E-value=0.19  Score=44.51  Aligned_cols=96  Identities=7%  Similarity=0.086  Sum_probs=47.9  Template_Neff=12.700

Q NP_000290.2     596 GLPQIAR-LLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ  674 (747)
Q Consensus       596 iI~~Ll~-LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e  674 (747)
                      .++.+.. ++.+.++.++..++.+|..+......   .....++.+...+.+      .++.++..++.+|..+..    
T Consensus        91 ~~~~l~~~~l~~~~~~vr~~a~~~l~~~~~~~~~---~~~~~~~~l~~~l~~------~~~~v~~~a~~~l~~~~~----  157 (280)
T 1OYZ_A           91 VFNILNNMALNDKSACVRATAIESTAQRCKKNPI---YSPKIVEQSQITAFD------KSTNVRRATAFAISVIND----  157 (280)
T ss_dssp             HHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHCGG---GHHHHHHHHHHHTTC------SCHHHHHHHHHHHHTC------
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHhcCcc---cChhHHHHHHHHhcC------CCHHHHHHHHHHHHhhcc----
Confidence            3444444 44444555555555555554432100   112244455555544      245566666666655442    


Q NP_000290.2     675 LAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMW  712 (747)
Q Consensus       675 ~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~  712 (747)
                             ...++.+..++.+. ++.++..++.++..+.
T Consensus       158 -------~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~  187 (280)
T 1OYZ_A          158 -------KATIPLLINLLKDP-NGDVRNWAAFAININK  187 (280)
T ss_dssp             --------CCHHHHHHHHTCS-SHHHHHHHHHHHHHHT
T ss_pred             -------hhhHHHHHHHHcCC-CHHHHHHHHHHHHhhc
Confidence                   12345555666655 6677777777777543


No 445
>5NR4_A CLIP-associating protein 2; Microtubules, TOG domain, Tubulin, Structural; 1.198A {Homo sapiens}
Probab=76.18  E-value=0.19  Score=42.69  Aligned_cols=111  Identities=10%  Similarity=0.045  Sum_probs=61.9  Template_Neff=12.900

Q NP_000290.2     595 KGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HR---V--MGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNL  668 (747)
Q Consensus       595 giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~---l--l~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnL  668 (747)
                      ..++.+...+.+.+..++..++..|..+...... ..   .  ....+++.+...+.+      .++.++..++.++..+
T Consensus         6 ~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l   79 (230)
T 5NR4_A            6 RSMEYFCAQVQQKDVGGRLQVGQELLLYLGAPGAISDLEEDLGRLGKTVDALTGWVGS------SNYRVSLMGLEILSAF   79 (230)
T ss_dssp             CCHHHHHHHTTCSCGGGHHHHHHHHHHHHHC-----CTTSCHHHHHHHHHHHHHHHHC------SSHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHhCCChhHHHHHHHHHHHHhcCCcccCchHHHHHHHHHHHHHHHHHHcC------CCHHHHHHHHHHHHHH
Confidence            3455566666667778888888888888765211 10   0  012345555666654      3677888888888888


Q NP_000290.2     669 MASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       669 a~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      +...+....... ..+++.++..+.+. +..++..++.++..++.
T Consensus        80 ~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~  122 (230)
T 5NR4_A           80 VDRLSTRFKSYV-AMVIVALIDRMGDA-KDKVRDEAQTLILKLMD  122 (230)
T ss_dssp             HHHHGGGGGGGH-HHHHHHHHHHTTCS-SHHHHHHHHHHHHHHHH
T ss_pred             HHHhhHHHHHHH-HHHHHHHHHHhccC-CHHHHHHHHHHHHHHHH
Confidence            764322111111 23445555555544 45566666666665553


No 446
>5A1V_E ADP-RIBOSYLATION FACTOR 1, COATOMER SUBUNIT; TRANSPORT PROTEIN, COPI, COATOMER, COATED; 21.0A {SACCHAROMYCES CEREVISIAE}
Probab=75.90  E-value=0.22  Score=54.55  Aligned_cols=137  Identities=11%  Similarity=0.073  Sum_probs=78.0  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|+.++. +.+..++..++.++..+....+.          . ..+++.|...+.+.++.++..++.+|..+.....
T Consensus        69 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~----------~-~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~~  136 (874)
T 5A1V_E           69 AFFAMTKLFQ-SNDPTLRRMCYLTIKEMSCIAED----------V-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTM  136 (874)
T ss_dssp             HHHHHHHGGG-SCCHHHHHHHHHHHHHHHTSCSC----------G-GGHHHHHHHHHHSSSHHHHHHHHHHHHHHCCHHH
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHhcccCch----------H-hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHHH
Confidence            4555666666 36667777777777776653211          1 2345566666666677777777777776643210


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.++..+....+...     ...++.+...+.+. ++.++..++.+
T Consensus       137 -----~~~l~~~l~~~l~d------~~~~Vr~~a~~~l~~l~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~  199 (874)
T 5A1V_E          137 -----LQAVERYMKQAIVD------KVPSVSSSALVSSLHLLKCSFDVV-----KRWVNEAQEAASSD-NIMVQYHALGL  199 (874)
T ss_dssp             -----HHHHHHHHHHHHTC------SSHHHHHHHHHHHHHHHHHCHHHH-----HHTHHHHHHHHTCC-SHHHHHHHHHH
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHH-----HHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 01234444455544      256677777777777765322111     13445555555544 56667777766


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..+..
T Consensus       200 L~~l~~  205 (874)
T 5A1V_E          200 LYHVRK  205 (874)
T ss_dssp             HHHHHC
T ss_pred             HHHHHh
Confidence            666654


No 447
>5NZR_G Coatomer subunit alpha, Coatomer subunit; COPI, coatomer, coated vesicles, Transport; 9.2A {Mus musculus}
Probab=75.90  E-value=0.22  Score=54.55  Aligned_cols=137  Identities=11%  Similarity=0.073  Sum_probs=78.0  Template_Neff=10.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.|+.++. +.+..++..++.++..+....+.          . ..+++.|...+.+.++.++..++.+|..+.....
T Consensus        69 l~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~----------~-~~i~~~l~~~L~~~~~~vr~~al~~L~~~~~~~~  136 (874)
T 5NZR_G           69 AFFAMTKLFQ-SNDPTLRRMCYLTIKEMSCIAED----------V-IIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTM  136 (874)
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHhcccCch----------H-hHHHHHHHHhcCCCChhhHHHHHHHHhhcCCHHH
Confidence            4555666666 36667777777777776653211          1 2345566666666677777777777776643210


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                           ...+++.+...+.+      .++.++..++.++..+....+...     ...++.+...+.+. ++.++..++.+
T Consensus       137 -----~~~l~~~l~~~l~d------~~~~Vr~~a~~~l~~l~~~~~~~~-----~~~~~~l~~~l~~~-~~~vr~~a~~~  199 (874)
T 5NZR_G          137 -----LQAVERYMKQAIVD------KVPSVSSSALVSSLHLLKCSFDVV-----KRWVNEAQEAASSD-NIMVQYHALGL  199 (874)
T ss_pred             -----HHHHHHHHHHHhcC------CCHHHHHHHHHHHHHHHhcCHHHH-----HHHHHHHHHHhcCC-CHHHHHHHHHH
Confidence                 01234444455544      256677777777777765322111     13445555555544 56667777766


Q NP_000290.2     708 LSDMWS  713 (747)
Q Consensus       708 LsnL~~  713 (747)
                      |..+..
T Consensus       200 L~~l~~  205 (874)
T 5NZR_G          200 LYHVRK  205 (874)
T ss_pred             HHHHHh
Confidence            666654


No 448
>6HWP_A A3_bGFPD; alphaRep, artificial protein, chimera, bidomain; 2.547A {synthetic construct}
Probab=75.54  E-value=0.21  Score=46.83  Aligned_cols=49  Identities=8%  Similarity=0.078  Sum_probs=32.0  Template_Neff=12.900

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.++..+..           ...++.+..++.+. ++.++..++.++..+...
T Consensus       129 ~~~vr~~~~~~l~~~~~-----------~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~  177 (409)
T 6HWP_A          129 DWFVRIAAAFALGEIGD-----------ERAVEPLIKALKDE-DGWVRQSAADALGEIGGE  177 (409)
T ss_dssp             SHHHHHHHHHHHHHHTC-----------GGGHHHHHHGGGCS-SHHHHHHHHHHHHHHCCH
T ss_pred             CHHHHHHHHHHHHHhCC-----------hhhHHHHHHHhcCC-CHHHHHHHHHHHHHhcch
Confidence            45666666666666543           12345566666655 678888888888887754


No 449
>3W3U_A Importin subunit beta-3; HEAT repeat, nuclear import, PROTEIN; 2.6A {Saccharomyces cerevisiae}
Probab=75.50  E-value=0.21  Score=53.79  Aligned_cols=152  Identities=16%  Similarity=0.150  Sum_probs=91.0  Template_Neff=13.000

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-PL  627 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~e  627 (747)
                      ++.+...+. +.++.++..++.+|..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. ..
T Consensus       358 ~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~  430 (1078)
T 3W3U_A          358 FQYLQQMIT-STEWRERFAAMMALSSAAAGCAD-----VLIG-EIPKILDMVIPLINDPHPRVQYGCCKVLGQISTAFSP  430 (1078)
T ss_dssp             HHHHHHHTT-CSSHHHHHHHHHHHHHHTTTTHH-----HHTT-SHHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTTT
T ss_pred             HHHHHHHhc-CCCHHHHHHHHHHHHHHHHccHH-----HHHh-hHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHHccH
Confidence            344445554 35677888888888888764321     0111 1135666677777777888999999999998865 11


Q NP_000290.2     628 L-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      . .......+++.+...+...     .+..++..++.+|..++..... ..... -..++..+...+.+. ++.++..++
T Consensus       431 ~~~~~~~~~~~~~l~~~l~~~-----~~~~vr~~a~~~l~~l~~~~~~~~~~~~-~~~~~~~l~~~l~~~-~~~~~~~~~  503 (1078)
T 3W3U_A          431 FIQRTAHDRILPALISKLTSE-----CTSRVQTHAAAALVAFSEFASKDILEPY-LDSLLTNLLVLLQSN-KLYVQEQAL  503 (1078)
T ss_dssp             HHHHHHHHHHHHHHHHHSSTT-----SCHHHHHHHHHHHHHHHTTCCHHHHGGG-HHHHHHHHHHHHTCS-SHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHcCCC-----CCHHHHHHHHHHHHHHHHhCChhhhHHH-HHHHHHHHHHHhcCC-CHHHHHHHH
Confidence            1 1111123555566655521     2567788888888888764221 11111 123556666666655 667777788


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .+|..++..
T Consensus       504 ~~l~~l~~~  512 (1078)
T 3W3U_A          504 TTIAFIAEA  512 (1078)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            887776643


No 450
>4QMI_B Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG domain; 1.9A {Homo sapiens}
Probab=75.47  E-value=0.21  Score=43.16  Aligned_cols=107  Identities=13%  Similarity=0.065  Sum_probs=67.9  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+........... ...+++.+...+.+.+..++..++.++..+.....     
T Consensus        59 ~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~-----  132 (240)
T 4QMI_B           59 ELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQH-VKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG-----  132 (240)
T ss_dssp             THHHHHHHHTTCSSHHHHHHHHHHHHHHHHHHGGGGGGG-CCCCCHHHHHHTTCSSHHHHHHHHHHHHHHHHHHC-----
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhcHHHHHH-HHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC-----
Confidence            344555556666777888888888888876533221111 12355666666666667788888888877765422     


Q NP_000290.2     325 TRRQNGI--REAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL--~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ...++  +.+...+. +.++.++..++.++..++..
T Consensus       133 --~~~~~~~~~l~~~l~-~~~~~~r~~~~~~l~~l~~~  167 (240)
T 4QMI_B          133 --MKEWLEGEDLSEELK-KENPFLRQELLGWLAEKLPT  167 (240)
T ss_dssp             --SHHHHSSSHHHHHHT-SCCHHHHHHHHHHHHHHGGG
T ss_pred             --hhHhccHHHHHHHHh-cCCHHHHHHHHHHHHHHHHh
Confidence              11244  55566665 55677888888888877653


No 451
>4QMJ_A Cytoskeleton-associated protein 5; PROTEIN BINDING, TOG DOMAIN; 2.498A {Homo sapiens}
Probab=75.47  E-value=0.21  Score=43.16  Aligned_cols=107  Identities=13%  Similarity=0.065  Sum_probs=67.9  Template_Neff=12.600

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+........... ...+++.+...+.+.+..++..++.++..+.....     
T Consensus        59 ~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~-----  132 (240)
T 4QMJ_A           59 ELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQH-VKNLGIPIITVLGDSKNNVRAAALATVNAWAEQTG-----  132 (240)
T ss_dssp             THHHHHHHHTTCSSHHHHHHHHHHHHHHHHHHGGGGGGG-CCCCCHHHHHGGGCSSHHHHHHHHHHHHHHHHHHC-----
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhcHHHHHH-HHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHhC-----
Confidence            344555556666777888888888888876533221111 12355666666666667788888888877765422     


Q NP_000290.2     325 TRRQNGI--REAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL--~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                        ...++  +.+...+. +.++.++..++.++..++..
T Consensus       133 --~~~~~~~~~l~~~l~-~~~~~~r~~~~~~l~~l~~~  167 (240)
T 4QMJ_A          133 --MKEWLEGEDLSEELK-KENPFLRQELLGWLAEKLPT  167 (240)
T ss_dssp             --SHHHHSSSHHHHHHH-SSCHHHHHHHHHHHHHHGGG
T ss_pred             --hhHhccHHHHHHHHh-cCCHHHHHHHHHHHHHHHHh
Confidence              11244  55566665 55677888888888877653


No 452
>2IX8_A ELONGATION FACTOR 3A; NUCLEOTIDE-BINDING, PROTEIN BIOSYNTHESIS, PHOSPHORYLATION, ELONGATION; 6.0A {SACCHAROMYCES CEREVISIAE}
Probab=75.43  E-value=0.22  Score=54.34  Aligned_cols=153  Identities=11%  Similarity=0.112  Sum_probs=91.2  Template_Neff=11.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.|+..+..+.++.++..++.+|..++.....     .... .-..+++.|..++.+.+..++..|+.+|..++... 
T Consensus       128 ~l~~l~~~l~~~~~~~vr~~al~~L~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~d~~~~vr~~a~~~l~~l~~~~~  201 (976)
T 2IX8_A          128 LLPHLTNAIVETNKWQEKIAILAAFSAMVDAAKD-----QVAL-RMPELIPVLSETMWDTKKEVKAAATAAMTKATETVD  201 (976)
T ss_dssp             HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHSHH-----HHHH-HHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHSTTCC
T ss_pred             HHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHHHH-----hHHh-hchhHHHHHHHhhcCCCHHHHHHHHHHHHHHHHhcC
Confidence            4556666662135667778888888888754221     1111 12356777778887778888888888888877531 


Q NP_000290.2     627 -LL-H----RVMG-----------------------------NQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       627 -e~-~----~ll~-----------------------------~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                       .. .    .++.                             ..+++.+...+.+      .++.++..++.+|..++..
T Consensus       202 ~~~~~~~~~~l~~~l~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~l~~l~~~l~~------~~~~vr~~a~~~L~~l~~~  275 (976)
T 2IX8_A          202 NKDIERFIPSLIQCIADPTEVPETVHLLGATTFVAEVTPATLSIMVPLLSRGLNE------RETGIKRKSAVIIDNMCKL  275 (976)
T ss_dssp             SSTTCCCHHHHHHHHHCGGGHHHHHHHCSCTTCCSCCCHHHHHHHHHHHHHHHTS------SSHHHHHHHHHHHHHHHTT
T ss_pred             cHHHHHHHHHHHHHhcCCCCchHHHHHHHHhhhhccCCchhHHHHHHHHHccCCC------CChhHHHHHHHHHHHHHHH
Confidence             00 0    0000                             0233344444443      3567888888888888764


Q NP_000290.2     672 QPQLAK-QYFSSSMLNNIINLCRSSAS-PKAAEAARLLLSDMWS  713 (747)
Q Consensus       672 s~e~~~-~Lve~giL~~Ll~LL~s~~d-~eVr~aAL~aLsnL~~  713 (747)
                      .+.... .-....+++.|...+.+. + +.++..++.+|..++.
T Consensus       276 ~~~~~~~~~~~~~~~~~l~~~l~d~-~~~~vr~~a~~~l~~l~~  318 (976)
T 2IX8_A          276 VEDPQVIAPFLGKLLPGLKSNFATI-ADPEAREVTLRALKTLRR  318 (976)
T ss_dssp             CCCHHHHHHHHTTTHHHHHHHHHHC-CCHHHHHHHHHHHHHHHH
T ss_pred             cCCHHHHHHHHHHHHHHHHHhcCCC-CCHHHHHHHHHHHHHHHH
Confidence            211110 001123566677777665 5 7888899999988865


No 453
>5XAH_A Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=75.38  E-value=0.21  Score=46.90  Aligned_cols=162  Identities=12%  Similarity=0.072  Sum_probs=86.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSG--------MSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASL  618 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~--------~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~a  618 (747)
                      +++.++..+. +.++.++..++.+|..++..... ...        ..... .-..+++.+...+.+ .++.++..++.+
T Consensus        33 i~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~~~~~~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~~  109 (416)
T 5XAH_A           33 VFEEVFKLLE-CPHLNVRKAAHEALGQFCCALHK-ACQSCPSEPNTAALQA-ALARVVPSYMQAVNRERERQVVMAVLEA  109 (416)
T ss_dssp             HHHHHHGGGS-CSCHHHHHHHHHHHHHHHHHHHH-HHTTSCCHHHHHHHHH-HHHHHHHHHHHHHTTCCCHHHHHHHHHH
T ss_pred             HHHHHHHHcC-CCCHHHHHHHHHHHHHHHHHHHH-HhccCCCCCCcHHHHH-HHHHHHHHHHHHHhhccHHHHHHHHHHH
Confidence            4566667776 46778888999999888764211 000        00000 112455666666655 567788889999


Q NP_000290.2     619 LSNMSRHPLLH-R---VMGNQVFPEVTRLLTSHTG--------------NTSNSEDILSSACYTVRNLMASQ-PQLAKQY  679 (747)
Q Consensus       619 LsnLa~~~e~~-~---ll~~giI~~Ll~LL~s~s~--------------~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~L  679 (747)
                      |..++...... .   .....+++.+...+.....              ....++.++..++.++..++... +.....+
T Consensus       110 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~  189 (416)
T 5XAH_A          110 LTGVLRSCGTLTLKPPGRLAELCGVLKAVLQRKTACQDTDEEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDSFAPF  189 (416)
T ss_dssp             HHHHHHHTTHHHHCSTTHHHHHHHHHHHHHTTCSTTC-------------CHHHHHHHHHHHHHHHHHHHHHTSTTTHHH
T ss_pred             HHHHHHHhcccccCCccHHHHHHHHHHHHHhccchhcCCCcccccccccHHHHHHHHHHHHHHHHHHHHHHhCccchHHH
Confidence            98887652111 0   1112345555555543100              00004567778888888887642 1111111


Q NP_000290.2     680 FSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       680 ve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      + ..+++.+...+....+..++..++.++..++.
T Consensus       190 ~-~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~  222 (416)
T 5XAH_A          190 F-AGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQ  222 (416)
T ss_dssp             H-HHHHHHHHHTTSSSSCHHHHHHHHHHHHHHHH
T ss_pred             H-HHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHH
Confidence            1 13455555555433135666777777776664


No 454
>5XAH_C Importin-4; Histone, Chromatin, Assembly, PROTEIN TRANSPORT; HET: MSE; 3.004A {Homo sapiens}
Probab=75.38  E-value=0.21  Score=46.90  Aligned_cols=162  Identities=12%  Similarity=0.072  Sum_probs=86.9  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSG--------MSQLIGLKEKGLPQIARLLQS-GNSDVVRSGASL  618 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~--------~~~~llie~giI~~Ll~LL~s-~d~eVr~~AL~a  618 (747)
                      +++.++..+. +.++.++..++.+|..++..... ...        ..... .-..+++.+...+.+ .++.++..++.+
T Consensus        33 i~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~~~~-~~~~~~~~~~~~~~~~-~~~~~~~~l~~~l~~~~~~~~~~~~~~~  109 (416)
T 5XAH_C           33 VFEEVFKLLE-CPHLNVRKAAHEALGQFCCALHK-ACQSCPSEPNTAALQA-ALARVVPSYMQAVNRERERQVVMAVLEA  109 (416)
T ss_dssp             HHHHHHHGGG-SSCHHHHHHHHHHHHHHHHHHHH-HHHHSCCHHHHHHHHH-HHHHHHHHHHHHHHHCCCHHHHHHHHHH
T ss_pred             HHHHHHHHcC-CCCHHHHHHHHHHHHHHHHHHHH-HhccCCCCCCcHHHHH-HHHHHHHHHHHHHhhccHHHHHHHHHHH
Confidence            4566667776 46778888999999888764211 000        00000 112455666666655 567788889999


Q NP_000290.2     619 LSNMSRHPLLH-R---VMGNQVFPEVTRLLTSHTG--------------NTSNSEDILSSACYTVRNLMASQ-PQLAKQY  679 (747)
Q Consensus       619 LsnLa~~~e~~-~---ll~~giI~~Ll~LL~s~s~--------------~~~~d~eVr~~Al~aLsnLa~~s-~e~~~~L  679 (747)
                      |..++...... .   .....+++.+...+.....              ....++.++..++.++..++... +.....+
T Consensus       110 l~~l~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~a~~~l~~l~~~~~~~~~~~~  189 (416)
T 5XAH_C          110 LTGVLRSCGTLTLKPPGRLAELCGVLKAVLQRKTACQDTDEEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGDSFAPF  189 (416)
T ss_dssp             HHHHHHHHGGGGSCSTTHHHHHHHHHHHHHHTCSTTTC-----------CTTHHHHHHHHHHTHHHHHHHHHTSTTTHHH
T ss_pred             HHHHHHHhcccccCCccHHHHHHHHHHHHHhccchhcCCCcccccccccHHHHHHHHHHHHHHHHHHHHHHhCccchHHH
Confidence            98887652111 0   1112345555555543100              00004567778888888887642 1111111


Q NP_000290.2     680 FSSSMLNNIINLCRSSASPKAAEAARLLLSDMWS  713 (747)
Q Consensus       680 ve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~  713 (747)
                      + ..+++.+...+....+..++..++.++..++.
T Consensus       190 ~-~~~~~~l~~~l~~~~~~~~~~~~~~~l~~l~~  222 (416)
T 5XAH_C          190 F-AGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQ  222 (416)
T ss_dssp             H-HHHHHHHHHTTSTTSCHHHHHHHHHHHHHHHH
T ss_pred             H-HHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHH
Confidence            1 13455555555433135666777777776664


No 455
>5H2V_A Importin subunit beta-3, Ubiquitin-like-specific protease; nuclear import, PROTEIN TRANSPORT-HYDROLASE complex; 2.8A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=75.07  E-value=0.22  Score=53.62  Aligned_cols=154  Identities=16%  Similarity=0.115  Sum_probs=91.6  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..++.....     .... .-..+++.+...+.+.++.++..++.++..++... 
T Consensus       357 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  429 (1078)
T 5H2V_A          357 LFQYLQQMIT-STEWRERFAAMMALSSAAEGCAD-----VLIG-EIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFS  429 (1078)
T ss_dssp             HHHHHHHHTT-CSCHHHHHHHHHHHHHHTTTTHH-----HHTT-SHHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhccHH-----HHHh-hHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHhhcc
Confidence            4555555565 35677888888888888764321     1111 11356666777777777889999999999988652 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. .......+++.+...+.+.     .++.++..++.+|..++...........-..++..+...+.+. ++.++..++
T Consensus       430 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~~~~~a~~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-~~~~~~~~~  503 (1078)
T 5H2V_A          430 PFIQRTAHDRILPALISKLTSE-----CTSRVQTHAAAALVNFSEFASKDILEPYLDSLLTNLLVLLQSN-KLYVQEQAL  503 (1078)
T ss_dssp             THHHHHHHHHHHHHHHHTTSTT-----SCHHHHHHHHHHHHHHHTTCCHHHHGGGHHHHHHHHHHHTTCS-SHHHHHHHH
T ss_pred             HHHHHHHHHhHHHHHHHHcccC-----CCHHHHHHHHHHHHHHHhcCChhhHHHHHHHHHHHHHHHHhCC-CHHHHHHHH
Confidence            11 1111123555555555431     2567788888888888764321110011123455666666554 567777777


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..++..
T Consensus       504 ~~l~~l~~~  512 (1078)
T 5H2V_A          504 TTIAFIAEA  512 (1078)
T ss_dssp             HHHHHHHHH
T ss_pred             HHHHHHHHH
Confidence            777776653


No 456
>6OWT_A AP-2 complex subunit alpha, AP-2; AP, HIV, Nef, trafficking, Protein;{Rattus norvegicus}
Probab=74.95  E-value=0.24  Score=54.59  Aligned_cols=140  Identities=16%  Similarity=0.153  Sum_probs=90.7  Template_Neff=11.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      +++.++.++. +.+...+..+..++..+......          ....++..|...+.+.++.++..|+.+|+++.....
T Consensus        75 ~~~~l~~ll~-s~~~~~r~~~~~~l~~l~~~~~~----------~~~~ii~~l~~~l~~~~~~vr~~Al~~l~~~~~~~~  143 (939)
T 6OWT_A           75 GHMEAVNLLS-SNRYTEKQIGYLFISVLVNSNSE----------LIRLINNAIKNDLASRNPTFMGLALHCIANVGSREM  143 (939)
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHccCChH----------HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhcCHHH
Confidence            3455666776 46667777777777777653221          112456667777777888899999999888764311


Q NP_000290.2     628 LHRVMGNQVFPEVTRLL--TSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL--~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                           ...+++.+..++  .+      .++.++..++.+|..+....+...   .....++.|..++.+. +..++..++
T Consensus       144 -----~~~l~~~l~~~l~~~~------~~~~vR~~a~~~L~~l~~~~~~~~---~~~~~~~~l~~lL~d~-~~~vr~~a~  208 (939)
T 6OWT_A          144 -----AEAFAGEIPKILVAGD------TMDSVKQSAALCLLRLYRTSPDLV---PMGDWTSRVVHLLNDQ-HLGVVTAAT  208 (939)
T ss_pred             -----HHHHHHHHHHHHcCCC------CCHHHHHHHHHHHHHHHHHCchhc---ChhhHHHHHHHHhcCC-CHHHHHHHH
Confidence                 112444555555  33      367889999999999876433221   1234567777777765 677888888


Q NP_000290.2     706 LLLSDMWS  713 (747)
Q Consensus       706 ~aLsnL~~  713 (747)
                      .+|..+..
T Consensus       209 ~~L~~l~~  216 (939)
T 6OWT_A          209 SLITTLAQ  216 (939)
T ss_pred             HHHHHHHH
Confidence            88877765


No 457
>4G3A_B CLIP-associating protein; TOG domain, HEAT repeat, MAP; HET: GOL; 1.994A {Drosophila melanogaster}
Probab=74.93  E-value=0.22  Score=42.89  Aligned_cols=107  Identities=15%  Similarity=0.166  Sum_probs=71.3  Template_Neff=12.600

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIA-RLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll-~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      .++.++..+. +.+..++..++.+|..+......          ....+++.+. .++.+.++.++..++.++..++...
T Consensus        91 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~~~----------~~~~~~~~l~~~~l~~~~~~~r~~a~~~l~~l~~~~  159 (237)
T 4G3A_B           91 VLPHVIDRLG-DSRDTVREKAQLLLRDLMEHRVL----------PPQALIDKLATSCFKHKNAKVREEFLQTIVNALHEY  159 (237)
T ss_dssp             HHHHHHHHHT-CSCHHHHHHHHHHHHHHHHTTSS----------CHHHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHHcCCC----------CHHHHHHHHHHHHhhCCCHHHHHHHHHHHHHHHHHh
Confidence            5666777776 35667788888888888753111          0123556666 6777777888999999998887652


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMAS  671 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~  671 (747)
                      .........+++.+...+.+      .++.++..++.++..+...
T Consensus       160 ~~~~~~~~~~~~~l~~~l~~------~~~~vr~~a~~~l~~l~~~  198 (237)
T 4G3A_B          160 GTQQLSVRVYIPPVCALLGD------PTVNVREAAIQTLVEIYKH  198 (237)
T ss_dssp             HHHHCCCGGGHHHHHHHTTC------SSHHHHHHHHHHHHHHHHH
T ss_pred             CCccccHHHHHHHHHHHHCC------CCHHHHHHHHHHHHHHHHH
Confidence            11111113456667777765      3678899999999988764


No 458
>4XL5_C Green fluorescent protein, bGFP-A; AlphaRep Scaffold, Complex, EGFP, PROTEIN; HET: CRO; 2.0A {Aequorea victoria}
Probab=74.58  E-value=0.23  Score=43.80  Aligned_cols=121  Identities=12%  Similarity=0.165  Sum_probs=73.5  Template_Neff=12.400

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.++..+...                ..++.+...+.+.++.++..++.+|..+...  
T Consensus       139 ~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~--  199 (263)
T 4XL5_C          139 AVEPLIKALK-DEDPWVRLTAARALGQIGDE----------------RAVEPLIKALKDEDASVRKAAAVALGQIGDE--  199 (263)
T ss_dssp             GHHHHHHHTT-CSSHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHCCG--
T ss_pred             hHHHHHHHhh-CCCHHHHHHHHHHHHhhCCH----------------HHHHHHHHHhcCCCHHHHHHHHHHHHHhCCh--
Confidence            4455666666 35667777777777655431                2234455566666677788888877766431  


Q NP_000290.2     628 LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLL  707 (747)
Q Consensus       628 ~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~a  707 (747)
                             ..++.+..++.+      .+..++..++.+|..+...           ...+.+..++.+. ++.++..++.+
T Consensus       200 -------~~~~~l~~~l~~------~~~~~~~~a~~~l~~~~~~-----------~~~~~l~~~~~~~-~~~vr~~a~~~  254 (263)
T 4XL5_C          200 -------RAVEPLIKALKD------EDEYVRQRAASALGKIGGE-----------RVRAAMEKLAEPA-PGFARKVAVNY  254 (263)
T ss_dssp             -------GGHHHHHHHTTC------SSHHHHHHHHHHHHHHCHH-----------HHHHHHHHHTTTC-CHHHHHHHHHH
T ss_pred             -------hhHHHHHHHhcC------CCHHHHHHHHHHHHhhCcH-----------HHHHHHHHHhcCC-CcHHHHHHHHH
Confidence                   234455555554      2566777888888776542           2334444555544 66788888888


Q NP_000290.2     708 LSDMW  712 (747)
Q Consensus       708 LsnL~  712 (747)
                      |..+.
T Consensus       255 l~~~~  259 (263)
T 4XL5_C          255 LETHK  259 (263)
T ss_dssp             HHHCC
T ss_pred             HHHHH
Confidence            77654


No 459
>4FDD_A Transportin-1, RNA-binding protein FUS; HEAT repeats, Karyopherin, nuclear import; 2.3A {Homo sapiens}
Probab=74.48  E-value=0.23  Score=51.35  Aligned_cols=155  Identities=9%  Similarity=0.106  Sum_probs=92.6  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIG--LKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~ll--ie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+. +.++.++..++.+|..+......   ......+  .-..+++.+...+.+.++.++..++.+|..++..
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~al~~l~~l~~~~~~---~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  204 (852)
T 4FDD_A          129 LLPKLCSLLD-SEDYNTCEGAFGALQKICEDSAE---ILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIIS  204 (852)
T ss_dssp             HHHHHHHHHS-CSSHHHHHHHHHHHHHHHHHHTT---HHHHCSSSSCHHHHHHHHTTTTTCSSHHHHHHHHHHHHTTTTT
T ss_pred             HHHHHHHHHc-CCCHHHHHHHHHHHHHHHHHHHh---hcchhhccHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            3455555565 35667777888888877753210   0000000  1134566677777777788899999999888765


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .++.++..++.++..+....+....... ..+++.+...+.+. ++.++..+
T Consensus       205 ~~~~~~~~~~~~~~~l~~~l~~------~~~~~r~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~v~~~a  276 (852)
T 4FDD_A          205 RTQALMLHIDSFIENLFALAGD------EEPEVRKNVCRALVMLLEVRMDRLLPHM-HNIVEYMLQRTQDQ-DENVALEA  276 (852)
T ss_dssp             TCHHHHTSHHHHHHHHHHHHTC------CCHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHTCS-SHHHHHHH
T ss_pred             hHHHHHHhHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcHHHHHHhH-HHHHHHHHHhcCCC-CHHHHHHH
Confidence            211 111112355556666654      3567888899999888765332211111 23456666666655 67788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.+|..++..
T Consensus       277 ~~~l~~l~~~  286 (852)
T 4FDD_A          277 CEFWLTLAEQ  286 (852)
T ss_dssp             HHHHHHHTTS
T ss_pred             HHHHHHHhcC
Confidence            8888887754


No 460
>4D4Z_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE, EIF-5A, HYPUSINE; HET: B3P, GOL; 1.7A {HOMO SAPIENS}
Probab=74.40  E-value=0.23  Score=44.22  Aligned_cols=124  Identities=11%  Similarity=0.101  Sum_probs=69.5  Template_Neff=12.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ...++.|...+. +.+  +.++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+.
T Consensus         9 ~~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~   71 (294)
T 4D4Z_A            9 EQEVDAIGQTLV-DPKQPLQARFRALFTLRGLGG----------------PGAIAWISQAFDDDSALLKHELAYCLGQMQ   71 (294)
T ss_dssp             HHHHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCS----------------HHHHHHHHHGGGCSCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc-CCCCCHHHHHHHHHHHHhhcC----------------hhHHHHHHHHhCCCCHHHHHHHHHHHHhcC
Confidence            345666777776 344  4577777777766532                123445556666667777888877777664


Q NP_000290.2     624 RHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       624 ~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      ..         ..++.+..++.+.    ..++.++..++.+|..+...           ..++.+...+.+. ++.++..
T Consensus        72 ~~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~v~~~  126 (294)
T 4D4Z_A           72 DA---------RAIPMLVDVLQDT----RQEPMVRHEAGEALGAIGDP-----------EVLEILKQYSSDP-VIEVAET  126 (294)
T ss_dssp             CG---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCG-----------GGHHHHHHHTTCS-SHHHHHH
T ss_pred             Cc---------chHHHHHHHhhCC----CCCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHccCC-CchHHHH
Confidence            31         2334455555441    01456777777777766431           1233444445444 5556666


Q NP_000290.2     704 ARLLLSDM  711 (747)
Q Consensus       704 AL~aLsnL  711 (747)
                      ++.++..+
T Consensus       127 a~~~l~~~  134 (294)
T 4D4Z_A          127 CQLAVRRL  134 (294)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            65555544


No 461
>4D50_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE; HET: GAI; 1.7A {HOMO SAPIENS}
Probab=74.40  E-value=0.23  Score=44.22  Aligned_cols=124  Identities=11%  Similarity=0.101  Sum_probs=69.5  Template_Neff=12.700

Q NP_000290.2     546 SDAIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       546 ~G~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ...++.|...+. +.+  +.++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+.
T Consensus         9 ~~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~   71 (294)
T 4D50_A            9 EQEVDAIGQTLV-DPKQPLQARFRALFTLRGLGG----------------PGAIAWISQAFDDDSALLKHELAYCLGQMQ   71 (294)
T ss_dssp             HHHHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCS----------------HHHHHHHHHGGGSSCHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHc-CCCCCHHHHHHHHHHHHhhcC----------------hhHHHHHHHHhCCCCHHHHHHHHHHHHhcC
Confidence            345666777776 344  4577777777766532                123445556666667777888877777664


Q NP_000290.2     624 RHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEA  703 (747)
Q Consensus       624 ~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~a  703 (747)
                      ..         ..++.+..++.+.    ..++.++..++.+|..+...           ..++.+...+.+. ++.++..
T Consensus        72 ~~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~v~~~  126 (294)
T 4D50_A           72 DA---------RAIPMLVDVLQDT----RQEPMVRHEAGEALGAIGDP-----------EVLEILKQYSSDP-VIEVAET  126 (294)
T ss_dssp             CG---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCG-----------GGHHHHHHHTTCS-SHHHHHH
T ss_pred             Cc---------chHHHHHHHhhCC----CCCHHHHHHHHHHHHHhCCH-----------HHHHHHHHHccCC-CchHHHH
Confidence            31         2334455555441    01456777777777766431           1233444445444 5556666


Q NP_000290.2     704 ARLLLSDM  711 (747)
Q Consensus       704 AL~aLsnL  711 (747)
                      ++.++..+
T Consensus       127 a~~~l~~~  134 (294)
T 4D50_A          127 CQLAVRRL  134 (294)
T ss_dssp             HHHHHHHH
T ss_pred             HHHHHHHH
Confidence            65555544


No 462
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=74.19  E-value=0.24  Score=50.25  Aligned_cols=69  Identities=16%  Similarity=0.194  Sum_probs=49.1  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+  . +.++.++..++.+|..+....+.        .......++.+..++.+.++.++..++.+|..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vr~~a~~~L~~l~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~L~~l~~~  217 (621)
T 6QH5_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  217 (621)
T ss_pred             HHHHHHHHhcCC-CCCHHHHHHHHHHHHHHHHhChH--------HccHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            355566666  5 46778888999999988764221        111245677788888888888999999999888764


No 463
>5LPH_B Centrosomal protein of 104 kDa; TOG domain, HEAT repeat, Tubulin; HET: MSE; 2.25A {Homo sapiens}
Probab=74.03  E-value=0.26  Score=45.88  Aligned_cols=155  Identities=10%  Similarity=0.057  Sum_probs=88.9  Template_Neff=10.900

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLM---SSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~---s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++.+...+. +.+..++..++.++..++......   ... .... .-..+++.|+..+.+.++.++..+..+|..++..
T Consensus        94 ~~~l~~~l~-d~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~-~l~~ll~~ll~~l~d~~~~vr~~a~~~l~~l~~~  170 (288)
T 5LPH_B           94 VFLVRRAIK-DIVTSVFQASLKLLKMIITQYIPKHKLSKL-ETAH-CVERTIPVLLTRTGDSSARLRVTAANFIQEMALF  170 (288)
T ss_pred             HHHHHHHhC-CCCHHHHHHHHHHHHHHHHHHcccCCCCHH-HHHH-HHHHHHHHHHHHhCCCcHHHHHHHHHHHHHHHcC
Confidence            444555565 466778888888888776532000   000 0011 1234667777777777788888899888888765


Q NP_000290.2     626 PLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       626 ~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .....  ...++..+...+...     .++.++..++.+|..++...........-..+++.+...+.+. +..+|..+.
T Consensus       171 ~~~~~--~~~v~~~l~~~l~~~-----~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~i~~~l~~~l~~~-~~~VR~~a~  242 (288)
T 5LPH_B          171 KEVKS--LQIIPSYLVQPLKAN-----SSVHLAMSQMGLLARLLKDLGTGSSGFTIDNVMKFSVSALEHR-VYEVRETAV  242 (288)
T ss_pred             CCCCc--hhhHHHHHhhccccC-----CCHHHHHHHHHHHHHHHHHHCCCCCCccHHHHHHHHHHHhCCC-CHHHHHHHH
Confidence            21100  011223332333321     2466777788888877654322111111224567777777766 789999999


Q NP_000290.2     706 LLLSDMWSS  714 (747)
Q Consensus       706 ~aLsnL~~~  714 (747)
                      .++..+...
T Consensus       243 ~~l~~l~~~  251 (288)
T 5LPH_B          243 RIILDMYRQ  251 (288)
T ss_pred             HHHHHHHHH
Confidence            998887653


No 464
>1QBK_B STRUCTURE OF THE KARYOPHERIN BETA2-RAN; HEAT REPEATS, NUCLEAR TRANSPORT PROTEIN; HET: GNP; 3.0A {Homo sapiens} SCOP: a.118.1.1
Probab=73.90  E-value=0.24  Score=51.58  Aligned_cols=156  Identities=9%  Similarity=0.104  Sum_probs=93.2  Template_Neff=13.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLI--GLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~l--lie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+. +.++.++..++.+|..++.....   ......  -.-..+++.+...+.+.++.++..++.+|..+...
T Consensus       129 ~~~~l~~~l~-~~~~~~~~~al~~l~~l~~~~~~---~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  204 (890)
T 1QBK_B          129 LLPKLCSLLD-SEDYNTCEGAFGALQKICEDSAE---ILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIIS  204 (890)
T ss_pred             HHHHHHHHhc-CCChhHHHHHHHHHHHHHHHHHH---hcchhhccHhHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            4555666665 35667777888888887754221   000000  01134566677777777788899999999988765


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .+..++..++.+|..++...+....... ..+++.+...+.+. ++.++..+
T Consensus       205 ~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~v~~~a  276 (890)
T 1QBK_B          205 RTQALMLHIDSFTENLFALAGD------EEPEVRKNVCRALVMLLEVRMDRLLPHM-HNIVEYMLQRTQDQ-DENVALEA  276 (890)
T ss_pred             hcHHHHHcHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHhCHHHHHHhH-HHHHHHHHHHhcCC-CHHHHHHH
Confidence            211 111112345555555554      2567788888888888765332221111 23456666666655 67788888


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.++..+....
T Consensus       277 ~~~l~~l~~~~  287 (890)
T 1QBK_B          277 CEFWLTLAEQP  287 (890)
T ss_pred             HHHHHHHhcCh
Confidence            88888887653


No 465
>3W3W_A Importin subunit beta-3, Protein STE12; HEAT repeat, nuclear import, PROTEIN; 2.2A {Saccharomyces cerevisiae}
Probab=73.86  E-value=0.24  Score=53.17  Aligned_cols=153  Identities=16%  Similarity=0.154  Sum_probs=90.7  Template_Neff=13.000

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH-P  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~-~  626 (747)
                      .++.+...+. +.++.++..++.+|..++.....     .... .-..+++.+...+.+.++.++..++.++..++.. .
T Consensus       357 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~-~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  429 (1078)
T 3W3W_A          357 LFQYLQQMIT-STEWRERFAAMMALSSAAEGCAD-----VLIG-EIPKILDMVIPLINDPHPRVQYGCCNVLGQISTDFS  429 (1078)
T ss_dssp             HHHHHHHHHT-CSCHHHHHHHHHHHHHHTTTTHH-----HHTT-CHHHHHHHHGGGGGCSSHHHHHHHHHHHHHHHHHTT
T ss_pred             HHHHHHHHhc-CCCHHHHHHHHHHHHHHHhccHH-----HHHh-hHHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcc
Confidence            4455555555 35677888888888888764221     1111 1135666677777777788999999999998865 1


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .. .......+++.+...+.+.     .+..++..++.+|..++..... ..... -..++..+...+.+. +..++..+
T Consensus       430 ~~~~~~~~~~~~~~l~~~l~~~-----~~~~~r~~a~~~l~~l~~~~~~~~~~~~-~~~i~~~l~~~l~~~-~~~~~~~~  502 (1078)
T 3W3W_A          430 PFIQRTAHDRILPALISKLTSE-----CTSRVQTHAAAALVNFSEFASKDILEPY-LDSLLTNLLVLLQSN-KLYVQEQA  502 (1078)
T ss_dssp             THHHHHHHHHHHHHHHHHTSTT-----SCHHHHHHHHHHHHHHHHTCCHHHHGGG-HHHHHHHHHHHHTCS-SHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHcccC-----CCHHHHHHHHHHHHHHHhcCChhhHHHH-HHHHHHHHHHHHhcC-CHHHHHHH
Confidence            11 1011123555555555431     2567788888888888764321 11111 123455666666544 56677777


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       503 ~~~l~~l~~~  512 (1078)
T 3W3W_A          503 LTTIAFIAEA  512 (1078)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            7777776643


No 466
>1IBR_B RAN  IMPORTIN BETA SUBUNIT; SMALL GTPASE  NUCLEAR TRANSPORT; HET: GNP; 2.3A {Homo sapiens} SCOP: a.118.1.1
Probab=73.63  E-value=0.25  Score=47.09  Aligned_cols=158  Identities=12%  Similarity=0.052  Sum_probs=89.8  Template_Neff=12.900

Q NP_000290.2     547 DAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSS------G-MSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       547 G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~------~-~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      +.++.++.++.+. .++.++..|+.+|.++...... ..      . .....-....+.+.++..+.+. +.++..++.+
T Consensus        35 ~~~~~l~~~l~~~~~~~~vr~~a~~~l~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~i~~~l~~~l~~~-~~~~~~~~~~  112 (462)
T 1IBR_B           35 TFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDP-DIKAQYQQRWLAIDANARREVKNYVLQTLGTE-TYRPSSASQC  112 (462)
T ss_dssp             HHHHHHHHHHHCTTSCHHHHHHHHHHHHHHHCCSSH-HHHHHHHHHHHTSCHHHHHHHHHHHHHHTTCC-CSSSCSHHHH
T ss_pred             HHHHHHHHHHhCCCCCHHHHHHHHHHHHHHhhcCCH-HHHHHHHHhHhcCCHHHHHHHHHHHHHHHCCC-CCChhHHHHH
Confidence            4566677777621 3567888888888887653210 00      0 0000001123445555555442 3457777788


Q NP_000290.2     619 LSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS--EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d--~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      ++.++...... .....+++.+...+.+      .+  +.++..++.+|..+...............+++.+...+.+. 
T Consensus       113 l~~l~~~~~~~-~~~~~~~~~l~~~l~~------~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  184 (462)
T 1IBR_B          113 VAGIACAEIPV-NQWPELIPQLVANVTN------PNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKE-  184 (462)
T ss_dssp             HHHHHHHHGGG-TCCTTHHHHHHHHHHC------TTCCHHHHHHHHHHHHHHHHHSCGGGTGGGHHHHHHHHHHHHSTT-
T ss_pred             HHHHHhhcCCh-hhcccHHHHHHHHhhC------CCCchHHHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHHHHhCC-
Confidence            88777541110 0112356666666665      23  67888899999888764322111111224567777777765 


Q NP_000290.2     697 S--PKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d--~eVr~aAL~aLsnL~~~  714 (747)
                      +  ..++..++.++..++..
T Consensus       185 ~~~~~vr~~a~~~l~~l~~~  204 (462)
T 1IBR_B          185 EPSNNVKLAATNALLNSLEF  204 (462)
T ss_dssp             CCCHHHHHHHHHHHHHHTTT
T ss_pred             CCCHHHHHHHHHHHHHHHHH
Confidence            4  78889999999888654


No 467
>5VCH_A Kap123; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.35A {Kluyveromyces lactis}
Probab=73.42  E-value=0.26  Score=53.37  Aligned_cols=153  Identities=15%  Similarity=0.124  Sum_probs=92.7  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      .++.+...+. +.++.++..++.+|..++.....     ..... -..+++.+...+.+.++.++..++.++..++... 
T Consensus       361 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  433 (1116)
T 5VCH_A          361 IIEHLPTMLS-SSNPFERRSILLAISVLVTGSPD-----YTLSQ-FDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQ  433 (1116)
T ss_dssp             HHHHHHHHHH-CSCHHHHHHHHHHHHHHTTTCHH-----HHHHT-HHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHSH
T ss_pred             HHHHHHHHhh-CCCHHHHHHHHHHHHHHHhcCHH-----HHHHh-HHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcH
Confidence            4555566665 35677788888888888764321     11111 1356677777777777889999999999888652 


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRS-SASPKAAEAA  704 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s-~~d~eVr~aA  704 (747)
                      .........+++.+...+...     .+..++..++.+|..++..... ...... ..+++.+...+.+ . ++.++..+
T Consensus       434 ~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~-~~~~~~~~  506 (1116)
T 5VCH_A          434 DEVARYHEQYLPLVIDIIDSA-----KHVVIYKYATLALDGLLEFIAHNDIIKYL-DPLMNKLFQMLETQQ-SPKLRAAI  506 (1116)
T ss_dssp             HHHHTTHHHHHHHHHHHHHTC-----CSHHHHHHHHHHHHHHHHTSCHHHHHHHH-HHHHHHHHHHHHHCC-CHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHhccC-----CCHHHHHHHHHHHHHHHhhCCHhhHHHHH-HHHHHHHHHHHhcCC-CHHHHHHH
Confidence            111111123555566665541     2567788888888888764222 111111 2356666666665 3 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       507 ~~~l~~l~~~  516 (1116)
T 5VCH_A          507 VSAIGSCAFA  516 (1116)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            8888777653


No 468
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=73.36  E-value=0.26  Score=49.97  Aligned_cols=69  Identities=16%  Similarity=0.194  Sum_probs=49.2  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+  . +.++.++..++.+|..+....+.        .......++.|..++.+.++.++..++.+|..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vr~~a~~~L~~~~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  217 (621)
T 6QH7_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  217 (621)
T ss_dssp             HTTHHHHHHTTS-CCCHHHHHHHHHHHHHHHHHCGG--------GCCCCTTHHHHHHGGGCSSHHHHHHHHHHHHHHHTT
T ss_pred             HHhhHHHHHHcC-CCCHHHHHHHHHHHHHHHHHChh--------hcCccchHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            455566666  5 46778888999999988764221        111245677788888888888999999999888764


No 469
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=73.28  E-value=0.27  Score=49.85  Aligned_cols=69  Identities=16%  Similarity=0.194  Sum_probs=49.0  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLM--GKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL--~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+  . +.++.++..++.+|..+....+.        .......++.|..++.+.++.++..++.+|..+...
T Consensus       147 l~~~l~~~l~~~-~~~~~vr~~a~~~L~~~~~~~~~--------~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  217 (623)
T 2JKT_A          147 FAGEIPKILVAG-DTMDSVKQSAALCLLRLYRTSPD--------LVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQK  217 (623)
T ss_dssp             HTTHHHHHHHCT-TSCHHHHHHHHHHHHHHHHHCTT--------TCCCCTHHHHHHGGGGCSSHHHHHHHHHHHHHHHTT
T ss_pred             HHHhHHHHHHcC-CCCHHHHHHHHHHHHHHHHHChh--------hcCccchHHHHHHHhcCCCHHHHHHHHHHHHHHHHH
Confidence            345566666  5 46778888999999888764221        111245677888888888888999999999888764


No 470
>1GCJ_B IMPORTIN-BETA; HEAT REPEAT MOTIF, NUCLEAR PORE-TARGETING; HET: MSE; 2.6A {Mus musculus} SCOP: a.118.1.1
Probab=73.02  E-value=0.27  Score=46.99  Aligned_cols=158  Identities=12%  Similarity=0.055  Sum_probs=87.6  Template_Neff=12.800

Q NP_000290.2     547 DAIRTYLNLMGKS-KKDATLEACAGALQNLTASKGLMSS------G-MSQLIGLKEKGLPQIARLLQSGNSDVVRSGASL  618 (747)
Q Consensus       547 G~I~~LL~LL~ss-~d~eVr~~AL~aL~nLs~~s~~~s~------~-~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~a  618 (747)
                      +.+..++..+.++ .+..++..|+.+|.++...... ..      . .....-....+.+.|+..+.+. ..++..++.+
T Consensus        41 ~~~~~l~~~l~~~~~~~~~r~~a~~~l~~~~~~~~~-~~~~~~~~~~~~l~~~~~~~l~~~l~~~l~~~-~~~r~~~~~~  118 (460)
T 1GCJ_B           41 TFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDP-DIKAQYQQRWLAIDANARREVKNYVLQTLGTE-TYRPSSASQC  118 (460)
T ss_dssp             HHHHHHHHHHSCTTSCHHHHHHHHHHHHTTTCCSSH-HHHHHHHHHHHHSCHHHHHHHHHHHHHHTTCC-CSSSCHHHHH
T ss_pred             HHHHHHHHHHhCCCCCHHHHHHHHHHHHHhccCCCH-HHHHHHHHHHHhCCHHHHHHHHHHHHHHHcCC-CCChhHHHHH
Confidence            3455666666521 2456777777888876643110 00      0 0000001233455566666543 3477778888


Q NP_000290.2     619 LSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNS--EDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSA  696 (747)
Q Consensus       619 LsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d--~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~  696 (747)
                      +..++...... .....+++.+...+.+      .+  +.++..++.+|..+...............+++.+...+.+. 
T Consensus       119 l~~l~~~~~~~-~~~~~~~~~l~~~l~~------~~~~~~~~~~~l~~l~~l~~~~~~~~~~~~~~~~~~~l~~~l~~~-  190 (460)
T 1GCJ_B          119 VAGIACAEIPV-SQWPELIPQLVANVTN------PNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKE-  190 (460)
T ss_dssp             HHHHHHHHGGG-TCCTTHHHHHHHHHHC------TTCCHHHHHHHHHHHHHHHHHSCHHHHGGGHHHHHHHHHHHHCTT-
T ss_pred             HHHHHHHhCCc-cccchHHHHHHHHhhC------CCCcHHHHHHHHHHHHHHhhhCCHHHhHHHHHHHHHHHHHHHhCC-
Confidence            88777541111 0112356666666665      23  67888899999888764221111111224566777777655 


Q NP_000290.2     697 S--PKAAEAARLLLSDMWSS  714 (747)
Q Consensus       697 d--~eVr~aAL~aLsnL~~~  714 (747)
                      +  ..++..++.++..+...
T Consensus       191 ~~~~~vr~~a~~~l~~~~~~  210 (460)
T 1GCJ_B          191 EPSNNVKLAATNALLNSLEF  210 (460)
T ss_dssp             CSCHHHHHHHHHHHHHHTTT
T ss_pred             CCCHHHHHHHHHHHHHHHHH
Confidence            4  78888888888887653


No 471
>1OYZ_A X-RAY STRUCTURE OF YB61_HAEIN NORTHEAST; STRUCTURAL GENOMICS, PSI, Protein Structure; 2.1A {Escherichia coli} SCOP: a.118.1.16
Probab=72.96  E-value=0.27  Score=43.42  Aligned_cols=121  Identities=14%  Similarity=0.056  Sum_probs=74.4  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP  626 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~  626 (747)
                      ..++.+...+. +.++.++..++.++..+....              ...++.+...+.+.++.++..++.+|..+... 
T Consensus       159 ~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~~~~--------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~~-  222 (280)
T 1OYZ_A          159 ATIPLLINLLK-DPNGDVRNWAAFAININKYDN--------------SDIRDCFVEMLQDKNEEVRIEAIIGLSYRKDK-  222 (280)
T ss_dssp             CCHHHHHHHHT-CSSHHHHHHHHHHHHHHTCCC--------------HHHHHHHHHHTTCSCHHHHHHHHHHHHHTTCG-
T ss_pred             hhHHHHHHHHc-CCCHHHHHHHHHHHHhhcCCC--------------hHHHHHHHHHhcCCCHHHHHHHHHHHhccCCh-
Confidence            34566677776 356677777777776553321              13455566667777778888888888776532 


Q NP_000290.2     627 LLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARL  706 (747)
Q Consensus       627 e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~  706 (747)
                              ..++.+...+.+        +.++..++.+|..+...           ..++.|...+.+..++.++..++.
T Consensus       223 --------~~~~~l~~~l~~--------~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~~~~~vr~~a~~  275 (280)
T 1OYZ_A          223 --------RVLSVLCDELKK--------NTVYDDIIEAAGELGDK-----------TLLPVLDTMLYKFDDNEIITSAID  275 (280)
T ss_dssp             --------GGHHHHHHHHTS--------SSCCHHHHHHHHHHCCG-----------GGHHHHHHHHTTSSCCHHHHHHHH
T ss_pred             --------hHHHHHHHHhCC--------ccHHHHHHHHHHHhcch-----------hHHHHHHHHHhcCCCHHHHHHHHH
Confidence                    234444455543        25677777777776531           245566666665226677888877


Q NP_000290.2     707 LLSD  710 (747)
Q Consensus       707 aLsn  710 (747)
                      +|..
T Consensus       276 ~l~~  279 (280)
T 1OYZ_A          276 KLKR  279 (280)
T ss_dssp             HHTC
T ss_pred             HHhc
Confidence            7764


No 472
>2JKT_A AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2; ALTERNATIVE SPLICING, PHOSPHOPROTEIN, PHOSPHORYLATION, PROTEIN; HET: SEP, SO4; 3.4A {MUS MUSCULUS}
Probab=72.80  E-value=0.28  Score=49.69  Aligned_cols=67  Identities=12%  Similarity=0.101  Sum_probs=35.9  Template_Neff=12.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa  623 (747)
                      .++.+..++. +.+..++..++.+|..+......      ...  -...++.++..+. +.++.++..++.+|..+.
T Consensus       330 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~  397 (623)
T 2JKT_A          330 ACNQLGQFLQ-HRETNLRYLALESMCTLASSEFS------HEA--VKTHIETVINALKTERDVSVRQRAVDLLYAMC  397 (623)
T ss_dssp             HHHHHHHHHH-SSCSHHHHHHHHHHHHHTTCSSS------CSG--GGGGHHHHHHHHHHCCSHHHHHHHHHHHHTTC
T ss_pred             HHHHHHHHhh-CCCchHHHHHHHHHHHHHcCcCC------HHH--HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhc
Confidence            3455556665 35566677777777766643210      011  1123445555555 555666666666666653


No 473
>5VE8_B Kap123, Histone H3; Bidding yeast karyopherin, 23 HEAT; HET: MSE; 2.7A {Kluyveromyces lactis}
Probab=72.66  E-value=0.27  Score=53.10  Aligned_cols=153  Identities=15%  Similarity=0.129  Sum_probs=92.5  Template_Neff=12.900

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPL  627 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e  627 (747)
                      .++.+...+. +.++.++..++.+|..++.....     ..... -..+++.+...+.+.++.++..++.++..++....
T Consensus       361 ~~~~l~~~l~-~~~~~~r~~a~~~l~~l~~~~~~-----~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~  433 (1116)
T 5VE8_B          361 IIEHLPTMLS-SSNPFERRSILLAISVLVTGSPD-----YTLSQ-FDKIIPATVTGLKDSEAVVQLAALKCIVQLSTNLQ  433 (1116)
T ss_dssp             HHHTHHHHHH-CSCHHHHHHHHHHHHHHHHHCHH-----HHHHT-HHHHHHHHHHHHTCSSHHHHHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHhh-CCCHHHHHHHHHHHHHHHhCCHH-----HHHHh-HHHHHHHHHHHccCCCHHHHHHHHHHHHHHHHhcH
Confidence            4555555665 35677788888888888764321     11111 13566777777777788899999999999886521


Q NP_000290.2     628 -LHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQ-LAKQYFSSSMLNNIINLCRS-SASPKAAEAA  704 (747)
Q Consensus       628 -~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e-~~~~Lve~giL~~Ll~LL~s-~~d~eVr~aA  704 (747)
                       ........+++.+...+...     .+..++..++.+|..++...+. ...... ..+++.+...+.+ . ++.++..+
T Consensus       434 ~~~~~~~~~~~~~l~~~l~~~-----~~~~v~~~a~~~l~~l~~~~~~~~~~~~~-~~~~~~l~~~l~~~~-~~~~~~~~  506 (1116)
T 5VE8_B          434 DEVARYHEQYLPLVIDIIDSA-----KHVVIYKYATLALDGLLEFIAHNDIIKYL-DPLMNKLFQMLETQQ-SPKLRAAI  506 (1116)
T ss_dssp             HHHHTTHHHHHHHHHHHHHTC-----CSHHHHHHHHHHHHHHHHTSCHHHHHHHH-HHHHHHHHHHHHHCC-CHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHhccC-----CCHHHHHHHHHHHHHHHhhcCHhhHHHHH-HHHHHHHHHHHhcCC-CHHHHHHH
Confidence             11111123555666665541     2567788888888888764222 111111 2356666666665 3 56777778


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       507 ~~~l~~l~~~  516 (1116)
T 5VE8_B          507 VSAIGSCAFA  516 (1116)
T ss_dssp             HHHHHHHHHH
T ss_pred             HHHHHHHHHH
Confidence            8888777653


No 474
>4ZV6_A AlphaRep-7, Octarellin V.1; synthetic gene, artificial protein, Rossmann-like; 2.22A {synthetic construct}
Probab=71.73  E-value=0.3  Score=43.65  Aligned_cols=29  Identities=17%  Similarity=0.240  Sum_probs=18.6  Template_Neff=12.500

Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.+...+.+. ++.++..++.++..+...
T Consensus       140 ~~~l~~~l~~~-~~~~r~~a~~~l~~~~~~  168 (294)
T 4ZV6_A          140 VEPLIKALKDE-DPYVRMAAAYALGKIGDE  168 (294)
T ss_pred             HHHHHHHhCCC-CHHHHHHHHHHHhhhCCH
Confidence            34455555554 667788888888776543


No 475
>6BZX_A alpha-Rep, Octarellin V.1; protein design, artificial protein, DE; 3.107A {synthetic construct}
Probab=71.39  E-value=0.31  Score=43.56  Aligned_cols=29  Identities=17%  Similarity=0.240  Sum_probs=18.5  Template_Neff=12.500

Q NP_000290.2     685 LNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       685 L~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.+...+.+. ++.++..++.++..+...
T Consensus       140 ~~~l~~~l~~~-~~~~r~~a~~~l~~~~~~  168 (294)
T 6BZX_A          140 VEPLIKALKDE-DPYVRMAAAYALGKIGDE  168 (294)
T ss_dssp             HHHHHHHTTCS-SHHHHHHHHHHHHHHTCG
T ss_pred             HHHHHHHhcCC-CHHHHHHHHHHHHHHcch
Confidence            34455555554 667788888887776543


No 476
>5IFE_C Splicing factor 3B subunit 5; pre-mRNA splicing, U2 snRNP, essential; 3.1A {Homo sapiens}
Probab=70.42  E-value=0.38  Score=55.84  Aligned_cols=154  Identities=9%  Similarity=0.047  Sum_probs=91.7  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      +++.|...+.+..++.++..++.+|..++.....     .... .-..+++.|...+.+.+..++..++.+|..++... 
T Consensus       644 ll~~L~~~l~s~~~~~~r~~al~~L~~l~~~~~~-----~~~~-~l~~ll~~L~~~L~d~~~~VR~~a~~~L~~l~~~~~  717 (1304)
T 5IFE_C          644 LLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGC-----AILP-HLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAAT  717 (1304)
T ss_pred             HHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHhhh-----hchh-hHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhCC
Confidence            4455555555222367788888888888753221     0111 11345666777777777889999999999988652 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.|+..+.+      ....++..++.+|..++..............++..|...+.+. +..++..++
T Consensus       718 ~~~~~~~-~~ll~~Ll~~l~~------~~~~v~~~~l~aL~~l~~~~~~~~~~~~~~~ll~~L~~~l~~~-~~~vr~~al  789 (1304)
T 5IFE_C          718 PYGIESF-DSVLKPLWKGIRQ------HRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP-DEEMKKIVL  789 (1304)
T ss_pred             HHHHHHH-HHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhcCHHHhhhHHHHHHHHHHHHhCCC-CHHHHHHHH
Confidence            11 1111 2345666666654      2456677788888877653221111111124566666777655 677888888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..++...
T Consensus       790 ~~L~~l~~~~  799 (1304)
T 5IFE_C          790 KVVKQCCGTD  799 (1304)
T ss_pred             HHHHHHHhcc
Confidence            8888877543


No 477
>6AHD_1 Pre-mRNA-processing-splicing factor 8, Thioredoxin-like protein; Spliceosome, SPLICING; HET: IHP, GTP; 3.8A {Homo sapiens}
Probab=70.42  E-value=0.38  Score=55.84  Aligned_cols=154  Identities=9%  Similarity=0.047  Sum_probs=91.7  Template_Neff=9.800

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHP-  626 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~-  626 (747)
                      +++.|...+.+..++.++..++.+|..++.....     .... .-..+++.|...+.+.+..++..++.+|..++... 
T Consensus       644 ll~~L~~~l~s~~~~~~r~~al~~L~~l~~~~~~-----~~~~-~l~~ll~~L~~~L~d~~~~VR~~a~~~L~~l~~~~~  717 (1304)
T 6AHD_1          644 LLPFLKAVCKSKKSWQARHTGIKIVQQIAILMGC-----AILP-HLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAAT  717 (1304)
T ss_pred             HHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHhhh-----hchh-hHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhCC
Confidence            4455555555222367788888888888753221     0111 11345666777777777889999999999988652 


Q NP_000290.2     627 LL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAAR  705 (747)
Q Consensus       627 e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL  705 (747)
                      .. ...+ ..+++.|+..+.+      ....++..++.+|..++..............++..|...+.+. +..++..++
T Consensus       718 ~~~~~~~-~~ll~~Ll~~l~~------~~~~v~~~~l~aL~~l~~~~~~~~~~~~~~~ll~~L~~~l~~~-~~~vr~~al  789 (1304)
T 6AHD_1          718 PYGIESF-DSVLKPLWKGIRQ------HRGKGLAAFLKAIGYLIPLMDAEYANYYTREVMLILIREFQSP-DEEMKKIVL  789 (1304)
T ss_pred             HHHHHHH-HHHHHHHHHHHhc------CCHHHHHHHHHHHHHHHHhcCHHHhhhHHHHHHHHHHHHhCCC-CHHHHHHHH
Confidence            11 1111 2345666666654      2456677788888877653221111111124566666777655 677888888


Q NP_000290.2     706 LLLSDMWSSK  715 (747)
Q Consensus       706 ~aLsnL~~~~  715 (747)
                      .+|..++...
T Consensus       790 ~~L~~l~~~~  799 (1304)
T 6AHD_1          790 KVVKQCCGTD  799 (1304)
T ss_pred             HHHHHHHhcc
Confidence            8888877543


No 478
>2QK2_A LP04448p; Mini spindles, Msps, XMAP215, Dis1; 2.1A {Drosophila melanogaster}
Probab=70.35  E-value=0.34  Score=41.59  Aligned_cols=113  Identities=7%  Similarity=-0.008  Sum_probs=66.2  Template_Neff=12.700

Q NP_000290.2     243 SGLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLL-RSPNQNVQQAAAGALRNLVFRSTTN  321 (747)
Q Consensus       243 ~~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL-~s~d~eVr~~AL~aLs~La~~~~~~  321 (747)
                      ...+++.+...+.+.++.++..++..+..+....+....... ..+++.+...+ .+.++.++..++.++..+.......
T Consensus        13 ~~~l~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~~~~~-~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~~~~~~~   91 (242)
T 2QK2_A           13 LSKMPKDFYDKLEEKKWTLRKESLEVLEKLLTDHPKLENGEY-GALVSALKKVITKDSNVVLVAMAGKCLALLAKGLAKR   91 (242)
T ss_dssp             GGGSCTTHHHHHTCSSHHHHHHHHHHHHHHHHHCSSBCCCCC-HHHHHHHHHHHHHCSCHHHHHHHHHHHHHHHHHHGGG
T ss_pred             hhhCCHHHHHHHhccchHHHHHHHHHHHHHHhhCcccccchH-HHHHHHHHHHHccCcHHHHHHHHHHHHHHHHHHhhHh
Confidence            344555666667777788888999988888764332111111 23566666667 6667788888888888877543322


Q NP_000290.2     322 KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLS  358 (747)
Q Consensus       322 ~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLa  358 (747)
                      .... ...+++.+...+. +.+..++..+..++..+.
T Consensus        92 ~~~~-~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~~~  126 (242)
T 2QK2_A           92 FSNY-ASACVPSLLEKFK-EKKPNVVTALREAIDAIY  126 (242)
T ss_dssp             GHHH-HHHHHHHHHHGGG-CCCHHHHHHHHHHHHHHH
T ss_pred             HHHH-HHhHHHHHHHHHh-cCCHHHHHHHHHHHHHHH
Confidence            1111 1234555555554 334455555555555544


No 479
>6MZG_E Tubulin alpha-1A chain, Tubulin beta; Microtubule, Tubulin, Tubulin polymerization, Heat; HET: GTP, GDP; 3.208A {Sus scrofa}
Probab=70.02  E-value=0.35  Score=47.53  Aligned_cols=71  Identities=15%  Similarity=0.238  Sum_probs=44.3  Template_Neff=12.700

Q NP_000290.2     549 IRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQ---LIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       549 I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~---~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      ++.++..+. +.++.++..++.+|..++.....   . ..   .. ....+++.+..++.+.++.++..++.+|..+...
T Consensus       138 ~~~l~~~l~-~~~~~vr~~~~~~l~~l~~~~~~---~-~~~~~~~-~~~~i~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  211 (554)
T 6MZG_E          138 VNLMLPSLS-NKLPRLVSSCVKCLATIIEEFGF---I-NVSDINI-LLSEILEPLPKLSSHADRNVRSETMNLILQIYKW  211 (554)
T ss_dssp             HHHHSGGGG-CSCHHHHHHHHHHHHHHHHHTCS---C-SCSCHHH-HHHHHHSSHHHHTTCSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHhc-CCCHHHHHHHHHHHHHHHHHhCC---C-ccccccc-cHHHHHHHHHHHhhcCCHHHHHHHHHHHHHHHHH
Confidence            444555555 35667777888888877653221   0 00   00 1235667777777777788888888888877654


No 480
>6QH7_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: SEP; 3.4A {Rattus norvegicus}
Probab=69.91  E-value=0.36  Score=48.86  Aligned_cols=100  Identities=18%  Similarity=0.054  Sum_probs=56.7  Template_Neff=12.200

Q NP_000290.2     247 IPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLETR  326 (747)
Q Consensus       247 L~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~ll  326 (747)
                      ++.+...+.+.++.++..++.++..+........     ..++..+...+.+.++.++..++.++..+....       .
T Consensus        76 ~~~l~~~l~~~~~~~r~~a~~~l~~~~~~~~~~~-----~~~~~~l~~~l~~~~~~vr~~al~~l~~~~~~~-------~  143 (621)
T 6QH7_A           76 HMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELI-----RLINNAIKNDLASRNPTFMGLALHCIANVGSRE-------M  143 (621)
T ss_dssp             HHHHHHHTTCSSHHHHHHHHHHHHHSCCCCHHHH-----HHHHHHHHHHHHSCCHHHHHHHHHHHHHHCCHH-------H
T ss_pred             HHHHHHHHcCCCccHHHHHHHHHHHHcCCCHHHH-----HHHHHHHHHHHhcCCHHHHHHHHHHHHhhCCHH-------H
Confidence            3344455555666677777777776654322111     123444555555666777777777777665321       0


Q NP_000290.2     327 RQNGIREAVSLL--RRTGNAEIQKQLTGLLWNLSS  359 (747)
Q Consensus       327 ~~~IL~~Ll~lL--~ss~d~eVr~~AL~aLsnLas  359 (747)
                      ...++..+...+  . +.++.++..++.++..+..
T Consensus       144 ~~~l~~~l~~~l~~~-~~~~~vr~~a~~~L~~~~~  177 (621)
T 6QH7_A          144 AEAFAGEIPKILVAG-DTMDSVKQSAALCLLRLYR  177 (621)
T ss_dssp             HHHHTTHHHHHHTTS-CCCHHHHHHHHHHHHHHHH
T ss_pred             HHHHHhhHHHHHHcC-CCCHHHHHHHHHHHHHHHH
Confidence            113444455555  4 4566777788888777765


No 481
>1UKL_A Importin beta-1 subunit/Sterol regulatory element; Transcription factor, Nuclear transport factor; HET: MSE; 3.0A {Mus musculus} SCOP: a.118.1.1
Probab=69.90  E-value=0.35  Score=50.26  Aligned_cols=154  Identities=11%  Similarity=0.064  Sum_probs=87.3  Template_Neff=13.100

Q NP_000290.2     548 AIRTYLNLMGKSKK--DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGN--SDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d--~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d--~eVr~~AL~aLsnLa  623 (747)
                      .++.+...+. +.+  +.++..++.+|..+......   . .... ....+++.+...+.+.+  +.++..++.++..+.
T Consensus       129 l~~~l~~~l~-~~~~~~~~~~~al~~l~~l~~~~~~---~-~~~~-~~~~l~~~l~~~l~~~~~~~~vr~~a~~~l~~~~  202 (876)
T 1UKL_A          129 LIPQLVANVT-NPNSTEHMKESTLEAIGYICQDIDP---E-QLQD-KSNEILTAIIQGMRKEEPSNNVKLAATNALLNSL  202 (876)
T ss_dssp             SHHHHHHHHH-STTCCHHHHHHHHHHHHHHHHHSCS---T-TTSS-SCHHHHHHHHHTTSTTCSCHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHhh-CCCCCHHHHHHHHHHHHHHhccCCH---H-HHHH-HHHHHHHHHHHHHhCCCCCHHHHHHHHHHHHHHH
Confidence            3455555565 233  56777788888777653221   0 0001 12346666777776655  778888888888876


Q NP_000290.2     624 RH-PLL-H-RVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKA  700 (747)
Q Consensus       624 ~~-~e~-~-~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eV  700 (747)
                      .. ... . ......++..+..++.+      .++.++..++.+|..+....+..........+++.+...+.+. ++.+
T Consensus       203 ~~~~~~~~~~~~~~~~~~~l~~~~~~------~~~~~r~~a~~~l~~l~~~~~~~~~~~~~~~l~~~l~~~l~~~-~~~v  275 (876)
T 1UKL_A          203 EFTKANFDKESERHFIMQVVCEATQC------PDTRVRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSD-IDEV  275 (876)
T ss_dssp             GGCHHHHHSHHHHHHHHHHHHHHTTS------SCHHHHHHHHHHHHHHHTTCGGGGHHHCCCCCHHHHHHHHHCS-CHHH
T ss_pred             HHhHHhcCCHHHHHHHHHHHHHHhCC------CCHHHHHHHHHHHHHHHHHHHHHhHHhchHHHHHHHHHHhhCC-CHHH
Confidence            54 111 0 01112233334444443      3577888899999888765333222122223456666666655 6778


Q NP_000290.2     701 AEAARLLLSDMWSS  714 (747)
Q Consensus       701 r~aAL~aLsnL~~~  714 (747)
                      +..++.++..+...
T Consensus       276 ~~~a~~~l~~l~~~  289 (876)
T 1UKL_A          276 ALQGIEFWSNVCDE  289 (876)
T ss_dssp             HHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHH
Confidence            88888888777653


No 482
>6EMK_C Serine/threonine-protein kinase TOR2 (E.C.2.7.1.67,2.7.11.1), Target; target of rapamycin, torc2, FRB; 8.0A {Saccharomyces cerevisiae (strain ATCC 204508 / S288c)}
Probab=69.88  E-value=0.38  Score=58.82  Aligned_cols=136  Identities=10%  Similarity=0.088  Sum_probs=72.9  Template_Neff=11.300

Q NP_000290.2     562 DATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLL-HRVMGNQVFPEV  640 (747)
Q Consensus       562 ~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~-~~ll~~giI~~L  640 (747)
                      +.++..++.+|..++.....   . ....  -..+++.|...+.+....++..+..++..+...... ...+ ..+++.+
T Consensus      1016 ~~vr~~a~~~l~~l~~~~~~---~-~~~~--~~~ll~~l~~~l~~~~~~~~~~~~~~l~~l~~~~~~~~~~l-~~i~~~l 1088 (2474)
T 6EMK_C         1016 IKLQITIISVIESISKALEG---E-FKRF--VPETLTFFLDILENDQSNKRIVPIRILKSLVTFGPNLEDYS-HLIMPIV 1088 (2474)
T ss_dssp             CCCCCCCSSCCCCCCSSCSC---C-SCCC--CCCCCTTHHHHCCCCCCCCCCCCCCCCHHHHHHCCCCCCCC-CCCTTHH
T ss_pred             hHHHHHHHHHHHHHHHHhhH---h-HHHH--HHHHHHHHHHHHhcCCCCCcchHHHHHHHHHHhhhhHHHHH-HHHHHHH
Confidence            34555666666666543221   0 0111  134556666666655445555555565555533111 1111 2244555


Q NP_000290.2     641 TRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       641 l~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      +..+..      .++.++..++.+|..++.....  .. ....++..+...+.+. ++.++..++.+|..++..
T Consensus      1089 ~~~l~~------~~~~vr~~a~~~l~~l~~~~~~--~~-~~~~i~~~l~~~l~~~-~~~vr~~a~~~l~~l~~~ 1152 (2474)
T 6EMK_C         1089 VRMTEY------SAGSLKKISIITLGRLAKNINL--SE-MSSRIVQALVRILNNG-DRELTKATMNTLSLLLLQ 1152 (2474)
T ss_dssp             HHCCCC------CCCCCTTTTTCCCCCCCCCCCC--CC-CCCCCCCCCCSCCCCC-CCCSSHHHHTTTCCGGGC
T ss_pred             HHHhcC------CCccHHHHHHHHHHHHHHhCCh--HH-HHHHHHHHHHHHHhcC-CHHHHHHHHHHHHHHHHH
Confidence            555554      2567888888888888754221  11 1123566666666654 667788888888777653


No 483
>4XL5_C Green fluorescent protein, bGFP-A; AlphaRep Scaffold, Complex, EGFP, PROTEIN; HET: CRO; 2.0A {Aequorea victoria}
Probab=69.87  E-value=0.36  Score=42.43  Aligned_cols=49  Identities=10%  Similarity=0.082  Sum_probs=29.3  Template_Neff=12.400

Q NP_000290.2     654 SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       654 d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                      ++.++..++.++..+..           ...++.+..++.+. ++.++..++.++..+...
T Consensus       120 ~~~~~~~a~~~l~~~~~-----------~~~~~~l~~~l~~~-~~~vr~~a~~~l~~~~~~  168 (263)
T 4XL5_C          120 DPWVRLTAARALGEIGD-----------ERAVEPLIKALKDE-DPWVRLTAARALGQIGDE  168 (263)
T ss_dssp             SHHHHHHHHHHHHHHCC-----------GGGHHHHHHHTTCS-SHHHHHHHHHHHHHHCCG
T ss_pred             CHHHHHHHHHHHHHHCC-----------hhhHHHHHHHhhCC-CHHHHHHHHHHHHhhCCH
Confidence            34455555555554432           12345555666655 678888888888877653


No 484
>4D4Z_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE, EIF-5A, HYPUSINE; HET: B3P, GOL; 1.7A {HOMO SAPIENS}
Probab=69.81  E-value=0.36  Score=42.88  Aligned_cols=127  Identities=10%  Similarity=0.093  Sum_probs=78.7  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDA--TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~e--Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++.|...+. +.+..  ++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+..
T Consensus       161 ~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~  223 (294)
T 4D4Z_A          161 RDVGRLREALL-DESRPLFERYRAMFALRNAGG----------------EEAALALAEGLHCGSALFRHEVGYVLGQLQH  223 (294)
T ss_dssp             CCHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCH----------------HHHHHHHHHGGGSSCHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHHH-hCCCCHHHHHHHHHHHHHcCC----------------HHHHHHHHHHhcCCCHHHHHHHHHHHHhcCC
Confidence            34566667776 34433  66677777665532                1234455666667777888888888877653


Q NP_000290.2     625 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       625 ~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .         ..++.+...+.+.    ..++.++..++.+|+.+...           ..++.|..++.+. ++.++..+
T Consensus       224 ~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a  278 (294)
T 4D4Z_A          224 E---------AAVPQLAAALARC----TENPMVRHECAEALGAIARP-----------ACLAALQAHADDP-ERVVRESC  278 (294)
T ss_dssp             G---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCH-----------HHHHHHHHHTTCS-SHHHHHHH
T ss_pred             h---------hHHHHHHHHHHhC----CCCHHHHHHHHHHHHHhccH-----------HHHHHHHHHhcCC-ChHHHHHH
Confidence            2         2344455555520    02567888888888876531           2455666667655 67788888


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.+|..+....
T Consensus       279 ~~~l~~~~~~~  289 (294)
T 4D4Z_A          279 EVALDMYEHET  289 (294)
T ss_dssp             HHHHHHHHHC-
T ss_pred             HHHHHHHHhhc
Confidence            88888776443


No 485
>4D50_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE; HET: GAI; 1.7A {HOMO SAPIENS}
Probab=69.81  E-value=0.36  Score=42.88  Aligned_cols=127  Identities=10%  Similarity=0.093  Sum_probs=79.0  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSKKDA--TLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMSR  624 (747)
Q Consensus       547 G~I~~LL~LL~ss~d~e--Vr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~  624 (747)
                      ..++.|...+. +.+..  ++..++.+|..+..                ...++.+...+.+.++.++..++.+|..+..
T Consensus       161 ~~~~~l~~~l~-~~~~~~~~r~~a~~~l~~~~~----------------~~~~~~l~~~l~~~~~~~r~~a~~~l~~~~~  223 (294)
T 4D50_A          161 RDVGRLREALL-DESRPLFERYRAMFALRNAGG----------------EEAALALAEGLHCGSALFRHEVGYVLGQLQH  223 (294)
T ss_dssp             CCHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCS----------------HHHHHHHHHGGGSSCHHHHHHHHHHHHHHCC
T ss_pred             HHHHHHHHHHH-hCCCCHHHHHHHHHHHHHcCC----------------HHHHHHHHHHhcCCCHHHHHHHHHHHHhcCC
Confidence            34566667776 34433  66677777665532                1234455666667777888888888877653


Q NP_000290.2     625 HPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       625 ~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      .         ..++.+...+.+.    ..++.++..++.+|+.+...           ..++.|..++.+. ++.++..+
T Consensus       224 ~---------~~~~~l~~~l~~~----~~~~~vr~~a~~~l~~~~~~-----------~~~~~l~~~l~~~-~~~vr~~a  278 (294)
T 4D50_A          224 E---------AAVPQLAAALARC----TENPMVRHECAEALGAIARP-----------ACLAALQAHADDP-ERVVRESC  278 (294)
T ss_dssp             G---------GGHHHHHHHHHCT----TSCHHHHHHHHHHHHHHCCH-----------HHHHHHHHTTTCS-CHHHHHHH
T ss_pred             h---------hHHHHHHHHHHhC----CCCHHHHHHHHHHHHHhccH-----------HHHHHHHHHhcCC-ChHHHHHH
Confidence            2         2344455555520    02567888888888876531           2455666667655 67788888


Q NP_000290.2     705 RLLLSDMWSSK  715 (747)
Q Consensus       705 L~aLsnL~~~~  715 (747)
                      +.+|..+....
T Consensus       279 ~~~l~~~~~~~  289 (294)
T 4D50_A          279 EVALDMYEHET  289 (294)
T ss_dssp             HHHHHHHHHHH
T ss_pred             HHHHHHHHhhc
Confidence            88888776443


No 486
>6QH5_A AP-2 complex subunit alpha, AP-2; ENDOCYTOSIS, PHOSPHORYLATION, CELL MEMBRANE, PROTEIN; HET: IHP; 2.56A {Rattus norvegicus}
Probab=69.69  E-value=0.37  Score=48.79  Aligned_cols=67  Identities=12%  Similarity=0.101  Sum_probs=37.3  Template_Neff=12.200

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQ-SGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~-s~d~eVr~~AL~aLsnLa  623 (747)
                      .++.+..++. +.++.++..++.+|..+......      ...  -...++.+...+. +.++.++..++.+|..+.
T Consensus       330 ~~~~l~~~l~-~~~~~vr~~a~~~L~~l~~~~~~------~~~--~~~~~~~l~~~l~~~~~~~vr~~a~~~l~~l~  397 (621)
T 6QH5_A          330 ACNQLGQFLQ-HRETNLRYLALESMCTLASSEFS------HEA--VKTHIETVINALKTERDVSVRQRAVDLLYAMC  397 (621)
T ss_pred             HHHHHHHHHh-CCCHHHHHHHHHHHHHHHhcCCC------hhH--HHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhc
Confidence            4555666665 35666777777777777653110      111  1224445555555 555666666666666653


No 487
>4XL5_C Green fluorescent protein, bGFP-A; AlphaRep Scaffold, Complex, EGFP, PROTEIN; HET: CRO; 2.0A {Aequorea victoria}
Probab=69.51  E-value=0.37  Score=42.33  Aligned_cols=88  Identities=10%  Similarity=0.162  Sum_probs=47.9  Template_Neff=12.400

Q NP_000290.2     600 IARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQY  679 (747)
Q Consensus       600 Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~L  679 (747)
                      +..++.+.++.++..++.++..+..         ...++.+...+.+      .++.++..++.+|..+..         
T Consensus       143 l~~~l~~~~~~vr~~a~~~l~~~~~---------~~~~~~l~~~l~~------~~~~~r~~a~~~l~~~~~---------  198 (263)
T 4XL5_C          143 LIKALKDEDPWVRLTAARALGQIGD---------ERAVEPLIKALKD------EDASVRKAAAVALGQIGD---------  198 (263)
T ss_dssp             HHHHTTCSSHHHHHHHHHHHHHHCC---------GGGHHHHHHHTTC------SSHHHHHHHHHHHHHHCC---------
T ss_pred             HHHHhhCCCHHHHHHHHHHHHhhCC---------HHHHHHHHHHhcC------CCHHHHHHHHHHHHHhCC---------
Confidence            3344444444555555555444432         1223344444444      245566667666666542         


Q NP_000290.2     680 FSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSS  714 (747)
Q Consensus       680 ve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~  714 (747)
                        ...++.+..++.+. +..++..++.++..+...
T Consensus       199 --~~~~~~l~~~l~~~-~~~~~~~a~~~l~~~~~~  230 (263)
T 4XL5_C          199 --ERAVEPLIKALKDE-DEYVRQRAASALGKIGGE  230 (263)
T ss_dssp             --GGGHHHHHHHTTCS-SHHHHHHHHHHHHHHCHH
T ss_pred             --hhhHHHHHHHhcCC-CHHHHHHHHHHHHhhCcH
Confidence              12345566666655 677888888888887753


No 488
>6LTJ_L Histone H3.2, Histone H4, Histone; Chromatin remodeler, Complex, GENE REGULATION; 3.7A {Xenopus laevis}
Probab=69.20  E-value=0.52  Score=55.12  Aligned_cols=106  Identities=11%  Similarity=0.124  Sum_probs=60.8  Template_Neff=5.100

Q NP_000290.2     609 SDVVRSGASLLSNMSRHPLL---HRVMGNQVFPEVTRLLTSHTGNTSNSE----------DILSSACYTVRNLMASQPQL  675 (747)
Q Consensus       609 ~eVr~~AL~aLsnLa~~~e~---~~ll~~giI~~Ll~LL~s~s~~~~~d~----------eVr~~Al~aLsnLa~~s~e~  675 (747)
                      ..+++.++.+|.||+...+.   ...+...++..|+.++...... ..++          ..+..|+.+|+.|+.. +.+
T Consensus      1064 ~~LRenaLviLaNIAg~LdLs~~~e~I~~~ild~LLhwlv~~sa~-a~Dp~~~~~~~~~lSp~~lALEaLsKLsv~-d~N 1141 (1295)
T 6LTJ_L         1064 EMLRENTLVTLANISGQLDLSPYPESICLPVLDGLLHWAVCPSAE-AQDPFSTLGPNAVLSPQRLVLETLSKLSIQ-DNN 1141 (1295)
T ss_dssp             HHHHHHHHHHHHHHGGGCCCSSSCHHHHHHHHHHHHHHHHCCSSS-SSSCCTTSCTTCCCCHHHHHHHHHHHHHTS-HHH
T ss_pred             HHHHHHHHHHHHHHHcccCCCCCChHhHHHHHHHHHHHHcCcChh-cCChhhccCCCCCCCHHHHHHHHHHHHhCC-Cch
Confidence            35667788889998876221   1111112455555544321000 0011          1234589999999874 555


Q NP_000290.2     676 AKQYFSSS-------MLNNIINLCRSSASPKAAEAARLLLSDMWSSKE  716 (747)
Q Consensus       676 ~~~Lve~g-------iL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~~  716 (747)
                      ...++...       ++..|+.+|....+..+++.++.+|.+|+...+
T Consensus      1142 ~dlLlat~p~srle~Ll~~LV~lL~~~ed~~lrE~AL~lL~~Ls~~~~ 1189 (1295)
T 6LTJ_L         1142 VDLILATPPFSRLEKLYSTMVRFLSDRKNPVCREMAVVLLANLAQGDS 1189 (1295)
T ss_dssp             HHHHHTSSCHHHHHHHHHHHHHHHHHCSSHHHHHHHHHHHHHHHHHCH
T ss_pred             HHHHHhCCCHHHHHHHHHHHHHHhcCCCCHHHHHHHHHHHHHHHcCCH
Confidence            55555433       566667777644245678899999999987543


No 489
>5WLC_LM rpS18_uS13, rpS4_eS4, rpS5_uS7, rpS6_eS6, rpS7_eS7; Ribosome assembly, RIBOSOME; 3.8A {Saccharomyces cerevisiae BY4741}
Probab=69.09  E-value=0.44  Score=57.42  Aligned_cols=153  Identities=6%  Similarity=-0.058  Sum_probs=85.4  Template_Neff=9.300

Q NP_000290.2     548 AIRTYLNLMGKS-----KKDATLEACAGALQNLTASKGLMSSGMSQL-IGLKEKGLPQIARLLQSGNSDVVRSGASLLSN  621 (747)
Q Consensus       548 ~I~~LL~LL~ss-----~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~-llie~giI~~Ll~LL~s~d~eVr~~AL~aLsn  621 (747)
                      +++.++..+...     .+..++..++.+|..++.....   ..... .. -..+++.|...+......++..++.++..
T Consensus      1597 ll~~l~~~L~~~~~~~~~~~~v~~~al~~L~~l~~~~~~---~~~~~~~~-~~~il~~L~~~L~~~~~~v~~~al~~L~~ 1672 (1769)
T 5WLC_LM        1597 LLEPVDMLLKRFISKDMENVNLRRLVINSLTSSLKFDRD---EYWKSTSR-FELISVSLVNQLSNIENSIGKYLVKAIGA 1672 (1769)
T ss_pred             HHHHHHHHHHHhcCCchhcHHHHHHHHHHHHHHHhhCCc---ccccCHhH-HHHHHHHHHHHHHccchHHHHHHHHHHHH
Confidence            455555555421     1356677888888887764221   00000 11 13456666666666556677778888888


Q NP_000290.2     622 MSRH-PLLHRVMGNQVFPEVTRLLTSHTGNTSN-SEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPK  699 (747)
Q Consensus       622 La~~-~e~~~ll~~giI~~Ll~LL~s~s~~~~~-d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~e  699 (747)
                      ++.. ....... ..+.+.++..+.+      . +..++..++.++..+..........+. ..+++.+.+.+.+. ++.
T Consensus      1673 L~~~~~~~~~~~-~~l~~~ll~~l~~------~~~~~vR~~al~~L~~l~~~~g~~~~~~l-~~il~~L~e~Led~-~~~ 1743 (1769)
T 5WLC_LM        1673 LASNNSGVDEHN-QILNKLIVEHMKA------SCSSNEKLWAIRAMKLIYSKIGESWLVLL-PQLVPVIAELLEDD-DEE 1743 (1769)
T ss_pred             HHHhccCChHHH-HHHHHHHHHHhcC------CCCHHHHHHHHHHHHHHHHHHChhHHHhH-hHHHHHHHHHccCC-CHH
Confidence            7653 1111111 1133344444433      2 567788888898888765332211111 24567777777765 677


Q NP_000290.2     700 AAEAA-RLLLSDMWS  713 (747)
Q Consensus       700 Vr~aA-L~aLsnL~~  713 (747)
                      ++..+ ..++..+..
T Consensus      1744 Vr~~a~~~~l~~L~~ 1758 (1769)
T 5WLC_LM        1744 IEREVRTGLVKVVEN 1758 (1769)
T ss_pred             HHHHHHHHHHHHHHH
Confidence            88888 777776654


No 490
>5YVI_A Transportin-1, RNA-binding protein FUS; Importin family, PROTEIN TRANSPORT, PROTEIN; 2.9A {Homo sapiens}
Probab=69.07  E-value=0.37  Score=49.71  Aligned_cols=155  Identities=9%  Similarity=0.106  Sum_probs=91.1  Template_Neff=13.300

Q NP_000290.2     548 AIRTYLNLMGKSKKDATLEACAGALQNLTASKGLMSSGMSQLIG--LKEKGLPQIARLLQSGNSDVVRSGASLLSNMSRH  625 (747)
Q Consensus       548 ~I~~LL~LL~ss~d~eVr~~AL~aL~nLs~~s~~~s~~~~~~ll--ie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~  625 (747)
                      .++.+...+. +.++.++..++.+|..++.....   ......+  .-..+++.+...+.+.++.++..++.+|..++..
T Consensus       131 ~~~~l~~~l~-~~~~~~~~~~l~~l~~l~~~~~~---~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~  206 (868)
T 5YVI_A          131 LLPKLCSLLD-SEDYNTCEGAFGALQKICEDSAE---ILDSDVLDRPLNIMIPKFLQFFKHSSPKIRSHAVACVNQFIIS  206 (868)
T ss_dssp             HHHHHHHHHT-CSSHHHHHHHHHHHHHHHHHHTT---CSCC--CCSTHHHHHHHHGGGGGCSSHHHHHHHHHHHHTTTTT
T ss_pred             HHHHHHHHhc-CCChHHHHHHHHHHHHHHHHHhh---hcchhhccHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHh
Confidence            4555666665 35667777888888887754211   0000000  0134566677777777788888999999888765


Q NP_000290.2     626 PLL-HRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQPQLAKQYFSSSMLNNIINLCRSSASPKAAEAA  704 (747)
Q Consensus       626 ~e~-~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aA  704 (747)
                      ... .......+++.+...+.+      .+..++..++.+|..++........... ..+++.+...+.+. ++.++..+
T Consensus       207 ~~~~~~~~~~~~~~~l~~~l~~------~~~~~~~~~~~~l~~l~~~~~~~~~~~~-~~~~~~l~~~l~~~-~~~v~~~~  278 (868)
T 5YVI_A          207 RTQALMLHIDSFIENLFALAGD------EEPEVRKNVCRALVMLLEVRMDRLLPHM-HNIVEYMLQRTQDQ-DENVALEA  278 (868)
T ss_dssp             TCHHHHTTHHHHHHHHHHTTTC------SSHHHHHHHHHHHHHHHHHCHHHHGGGH-HHHHHHHHHHHTCS-SHHHHHHH
T ss_pred             chHHHHHhHHHHHHHHHHHcCC------CCHHHHHHHHHHHHHHHHHcHHHHHHhH-HHHHHHHHHHccCC-CHHHHHHH
Confidence            211 111112345555555544      2567788888888888764322111111 23456666666655 67788888


Q NP_000290.2     705 RLLLSDMWSS  714 (747)
Q Consensus       705 L~aLsnL~~~  714 (747)
                      +.++..++..
T Consensus       279 ~~~l~~l~~~  288 (868)
T 5YVI_A          279 CEFWLTLAEQ  288 (868)
T ss_dssp             HHHHHHHHHS
T ss_pred             HHHHHHHhcC
Confidence            8888887764


No 491
>3VWA_A Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; 2.2A {Saccharomyces cerevisiae}
Probab=68.93  E-value=0.42  Score=49.31  Aligned_cols=111  Identities=9%  Similarity=0.051  Sum_probs=80.6  Template_Neff=10.600

Q NP_000290.2     594 EKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       594 ~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      ..+++.+..++.+.++.++..++..|..++.... .......+++.+...+.+      .+..++..++.+|..++...+
T Consensus       340 ~~~~~~l~~ll~~~~~~vR~~~~~~l~~~~~~~~-~~~~~~~~~~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~  412 (560)
T 3VWA_A          340 VGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLS-KSEISSRIYPHFIQGLTD------SDATLRLQTLKTIPCIVSCLT  412 (560)
T ss_dssp             TTHHHHHHHHHHCCCHHHHHHHHHHHHHHBTTBC-HHHCCCCCHHHHHHGGGC------SSHHHHHHHHHHHHHHGGGCC
T ss_pred             cchHHHHHHHcCCCCHHHHHHHHHhHHHHhccCC-HHHHHhchHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCC
Confidence            4577888888888888999999999888876411 112234567777777766      367889999999999886432


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      ..   .....+++.+..++.+. ++.++..++.+|..++...
T Consensus       413 ~~---~~~~~ll~~l~~~l~d~-~~~vR~~a~~~l~~i~~~~  450 (560)
T 3VWA_A          413 ER---QLNNELLRFLAKTQVDS-DVEIRTWTVIIISKISTIL  450 (560)
T ss_dssp             HH---CCCCCCHHHHHHHTTCS-SHHHHHHHHHHHHHHGGGS
T ss_pred             HH---HHHHHHHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHh
Confidence            11   22345677888888766 7899999999999887544


No 492
>3VWA_B Cytoplasmic export protein 1; tRNA, nuclear export, HEAT repeat; HET: MSE; 2.2A {Saccharomyces cerevisiae}
Probab=68.86  E-value=0.42  Score=49.21  Aligned_cols=111  Identities=9%  Similarity=0.062  Sum_probs=80.6  Template_Neff=10.700

Q NP_000290.2     594 EKGLPQIARLLQSGNSDVVRSGASLLSNMSRHPLLHRVMGNQVFPEVTRLLTSHTGNTSNSEDILSSACYTVRNLMASQP  673 (747)
Q Consensus       594 ~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa~~~e~~~ll~~giI~~Ll~LL~s~s~~~~~d~eVr~~Al~aLsnLa~~s~  673 (747)
                      ..+++.+..++.+.++.++..++..|..++.... .......+++.++..+.+      .++.++..++.+|..++...+
T Consensus       340 ~~~~~~l~~l~~~~~~~vr~~~~~~l~~~~~~~~-~~~~~~~~l~~l~~~l~d------~~~~vr~~a~~~l~~l~~~~~  412 (560)
T 3VWA_B          340 VGFNDLITQSFKLPDRQVRFLLLIYLPKLIGPLS-KSEISSRIYPHFIQGLTD------SDATLRLQTLKTIPCIVSCLT  412 (560)
T ss_dssp             TTHHHHHHHHHHCCCHHHHHHHHHHHHHHBTTBC-HHHCCCCCHHHHHHGGGC------SCHHHHHHHHHHHHHHGGGSC
T ss_pred             cchHHHHHHHcCCCcHHHHHHHHHhHHHHhhhCC-HHHHhhchHHHHHHHhcC------CCHHHHHHHHHHHHHHHhhCC
Confidence            4577888888888888899999998888876421 112234567777777776      368899999999999886422


Q NP_000290.2     674 QLAKQYFSSSMLNNIINLCRSSASPKAAEAARLLLSDMWSSK  715 (747)
Q Consensus       674 e~~~~Lve~giL~~Ll~LL~s~~d~eVr~aAL~aLsnL~~~~  715 (747)
                      .   ......+++.|..++.+. ++.++..++.+|..++...
T Consensus       413 ~---~~~~~~ll~~l~~~l~d~-~~~vR~~a~~~l~~i~~~~  450 (560)
T 3VWA_B          413 E---RQLNNELLRFLAKTQVDS-DVEIRTWTVIIISKISTIL  450 (560)
T ss_dssp             H---HCCCCCHHHHHHHHTTCS-SHHHHHHHHHHHHHHHTTS
T ss_pred             H---HHHHHHHHHHHHHHcCCC-CHHHHHHHHHHHHHHHHHh
Confidence            1   122335678888888776 7899999999999887643


No 493
>3C5W_A PP2A A subunit, PP2A C; methylesterase, phosphatase, PP2A, HYDROLASE; 2.8A {Homo sapiens}
Probab=68.82  E-value=0.38  Score=40.27  Aligned_cols=109  Identities=12%  Similarity=0.007  Sum_probs=69.9  Template_Neff=13.200

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      ..++.+...+.+.++.++..++..+..+.......   .....+++.+...+.+.++.++..++.++..+.......   
T Consensus         7 ~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~~---~~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~l~~~~~~~---   80 (232)
T 3C5W_A            7 YPIAVLIDELRNEDVQLRLNSIKKLSTIALALGVE---RLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVE---   80 (232)
T ss_dssp             SHHHHHHHHHTCSSHHHHHHHHTTHHHHHHHHCSS---HCCCCCHHHHHHHTTCSSHHHHHHHHTTHHHHHHHHCGG---
T ss_pred             cHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhChH---HHHHhHHHHHHHHHhCCCHHHHHHHHHHHHHHHHhhCHH---
Confidence            44556666777777888888888888876543211   112345666666677777788888888888776543211   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. +.++.++..++.++..+...
T Consensus        81 ~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  115 (232)
T 3C5W_A           81 FFDEKLNSLCMAWLV-DHVYAIREAATSNLKKLVEK  115 (232)
T ss_dssp             GTTTTHHHHHHHHTT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHh-CCCHHHHHHHHHHHHHHHHH
Confidence            112235555666665 45677888888888877754


No 494
>4K92_B CLIP-associating protein 1; HEAT-Repeat TOG domain, Regulator of; HET: MSE; 2.005A {Homo sapiens}
Probab=68.63  E-value=0.41  Score=43.13  Aligned_cols=109  Identities=12%  Similarity=0.075  Sum_probs=66.8  Template_Neff=11.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.++..+.+.+..++..++.++..+.....       ...+++.+...+.+.++.++..++.++..++........
T Consensus       129 ~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~-------~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~~~~~  201 (273)
T 4K92_B          129 EAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH-------IPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL  201 (273)
T ss_dssp             HHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC-------CTTHHHHHHGGGGCSCHHHHHHHHHHHHHHHHHSCHHHH
T ss_pred             HHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC-------CchHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHcCchhH
Confidence            3445555555555566677777777777765321       123455555666666677888888888877754322100


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ......+++.+...+. +.+..++..++.++..+...
T Consensus       202 ~~~~~~i~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~  237 (273)
T 4K92_B          202 ERHISVLAETIKKGIH-DADSEARIEARKCYWGFHSH  237 (273)
T ss_dssp             TTCHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            1112345566666665 55778888888888888764


No 495
>6MQ7_B CLIP-associating protein 1; microtubule binding protein, STRUCTURAL PROTEIN; 1.78A {Homo sapiens}
Probab=68.63  E-value=0.41  Score=43.13  Aligned_cols=109  Identities=12%  Similarity=0.075  Sum_probs=66.8  Template_Neff=11.700

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      ..+++.++..+.+.+..++..++.++..+.....       ...+++.+...+.+.++.++..++.++..++........
T Consensus       129 ~~~l~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~-------~~~~~~~l~~~l~~~~~~~r~~~~~~l~~l~~~~~~~~~  201 (273)
T 6MQ7_B          129 EAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTH-------IPRLIPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSL  201 (273)
T ss_dssp             HHHHHHHHTTTTCSSHHHHHHHHHHHHHHHHHCC-------CGGGHHHHHHGGGCSCHHHHHHHHHHHHHHHHHSCGGGT
T ss_pred             HHHHHHHHHHCccccHHHHHHHHHHHHHHHHhCC-------CchHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHcCchhH
Confidence            3445555555555566677777777777765321       123455555666666677888888888877754322100


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      ......+++.+...+. +.+..++..++.++..+...
T Consensus       202 ~~~~~~i~~~l~~~l~-d~~~~vr~~a~~~l~~l~~~  237 (273)
T 6MQ7_B          202 ERHISVLAETIKKGIH-DADSEARIEARKCYWGFHSH  237 (273)
T ss_dssp             TTCHHHHHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            1112345566666665 55778888888888888764


No 496
>4LAC_A Serine/threonine-protein phosphatase 2A activator (E.C.5.2.1.8); PP2A, PTPA, protein phosphatase, signaling; HET: AGS, MES; 2.82A {Homo sapiens}
Probab=68.25  E-value=0.41  Score=41.40  Aligned_cols=109  Identities=7%  Similarity=-0.006  Sum_probs=68.9  Template_Neff=12.800

Q NP_000290.2     245 LTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKLE  324 (747)
Q Consensus       245 ~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~~  324 (747)
                      .+++.+...+.+.++.++..++.++..+......   ......+++.+...+.+.+..++..++.++..+.......   
T Consensus       111 ~~~~~l~~~l~~~~~~vr~~a~~~l~~~~~~~~~---~~~~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~~---  184 (258)
T 4LAC_A          111 KLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGK---EWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQD---  184 (258)
T ss_pred             HHHHHHHHHhcCCCHHHHHHHHHHHHHHHHcCCh---hHHHHhHHHHHHHHcCCCCHHHHHHHHHHHHHHHHcCCCC---
Confidence            3455556666666778888888888887654322   1112345566666666667778888888888776543221   


Q NP_000290.2     325 TRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       325 ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                      .....+++.+...+. +.++.++..++.++..+...
T Consensus       185 ~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  219 (258)
T 4LAC_A          185 ITTKHMLPTVLRMAG-DPVANVRFNVAKSLQKIGPI  219 (258)
T ss_pred             ccHhhHHHHHHHHhc-CCCHHHHHHHHHHHHHHHHH
Confidence            112345566666665 55677888888888887653


No 497
>6MQ5_A CLIP-associating protein 1; Microtubule Plus End Binding, STRUCTURAL; HET: MSE; 2.146A {Homo sapiens}
Probab=68.04  E-value=0.43  Score=42.33  Aligned_cols=108  Identities=10%  Similarity=0.048  Sum_probs=65.9  Template_Neff=11.900

Q NP_000290.2     245 LTIPKAV-QYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTNKL  323 (747)
Q Consensus       245 ~iL~~Ll-~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~~~  323 (747)
                      .++..+. .++.+.++.++..++.++..+........... ...+++.+...+.+.+..++..+..++..+......   
T Consensus        49 ~~~~~l~~~~l~d~~~~vr~~a~~~l~~l~~~~~~~~~~~-~~~~~~~l~~~l~~~~~~vr~~a~~~l~~l~~~~~~---  124 (257)
T 6MQ5_A           49 KLVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQ-IGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQAAN---  124 (257)
T ss_dssp             HHHHHCCCCCTTCSSHHHHHHHHHHHHHHHHHHGGGGHHH-HHHHHHHHHHHTTCSCHHHHHHHHHHHHHHHHHTSC---
T ss_pred             HHHHHHHHHHhcCCcHHHHHHHHHHHHHHHHHhHHHHHHH-HHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHccC---
Confidence            3444444 44556677788888888888876433221111 134566666666666677788888888777643211   


Q NP_000290.2     324 ETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       324 ~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                         ...+++.+...+. ..++.++..++.++..+...
T Consensus       125 ---~~~~~~~l~~~l~-~~~~~~r~~~l~~l~~l~~~  157 (257)
T 6MQ5_A          125 ---PQYVWDRMLGGFK-HKNFRTREGICLCLIATLNA  157 (257)
T ss_dssp             ---HHHHHHTTGGGGG-BSSHHHHHHHHHHHHHHHHH
T ss_pred             ---hHHHHHHHhhhcC-CCCHHHHHHHHHHHHHHHHH
Confidence               1234555555564 45677888888888877653


No 498
>2QK1_A Protein STU2; stu2, Stu2p, XMAP215, Dis1, TOG; 1.7A {Saccharomyces cerevisiae}
Probab=67.88  E-value=0.42  Score=40.93  Aligned_cols=116  Identities=3%  Similarity=-0.016  Sum_probs=68.4  Template_Neff=12.900

Q NP_000290.2     244 GLTIPKAVQYLSSQDEKYQAIGAYYIQHTCFQDESAKQQVYQLGGICKLVDLLRSPNQNVQQAAAGALRNLVFRSTTN--  321 (747)
Q Consensus       244 ~~iL~~Ll~lL~ssd~eVr~sAL~aLsnLs~~~~~~~~~li~~~IL~~Ll~lL~s~d~eVr~~AL~aLs~La~~~~~~--  321 (747)
                      ..+++.+...+.+.+..++..++.++..+...............+++.+...+.+.++.++..++.++..++......  
T Consensus       103 ~~~~~~l~~~l~~~~~~v~~~a~~~l~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~vr~~~~~~l~~~~~~~~~~~~  182 (249)
T 2QK1_A          103 SLVFTPLLDRTKEKKPSVIEAIRKALLTICKYYDPLASSGRNEDMLKDILEHMKHKTPQIRMECTQLFNASMKEEKDGYS  182 (249)
T ss_dssp             HHHHHHHHHGGGCCCHHHHHHHHHHHHHHHHHSCTTCTTCTTHHHHHHHHHHTTCSSHHHHHHHHHHHHHHHHHCCSCSH
T ss_pred             HHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHhChhcccCCHHHHHHHHHHHhCCCCHHHHHHHHHHHHHHHHhccccch
Confidence            345556666666666777888888888776543210000111245566666666667778888888888776543310  


Q NP_000290.2     322 -KLETRRQNGIREAVSLLRRTGNAEIQKQLTGLLWNLSST  360 (747)
Q Consensus       322 -~~~ll~~~IL~~Ll~lL~ss~d~eVr~~AL~aLsnLas~  360 (747)
                       ........+++.+...+. +.++.++..++.++..+...
T Consensus       183 ~~~~~~~~~~~~~l~~~l~-~~~~~vr~~a~~~l~~l~~~  221 (249)
T 2QK1_A          183 TLQRYLKDEVVPIVIQIVN-DTQPAIRTIGFESFAILIKI  221 (249)
T ss_dssp             HHHHHCCCCCHHHHHHHHT-CSSHHHHHHHHHHHHHHHHH
T ss_pred             hhhHHHHHHHHHHHHHHHc-CCCHHHHHHHHHHHHHHHHH
Confidence             000111235555666665 55677888888888877653


No 499
>4D4Z_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE, EIF-5A, HYPUSINE; HET: B3P, GOL; 1.7A {HOMO SAPIENS}
Probab=67.63  E-value=0.43  Score=42.31  Aligned_cols=60  Identities=10%  Similarity=0.123  Sum_probs=34.5  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|...+. +.  ++.++..++.+|..+...                ..++.+...+.+.++.++..++.+|..+.
T Consensus        74 ~~~~~l~~~l~-~~~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~v~~~a~~~l~~~~  135 (294)
T 4D4Z_A           74 RAIPMLVDVLQ-DTRQEPMVRHEAGEALGAIGDP----------------EVLEILKQYSSDPVIEVAETCQLAVRRLE  135 (294)
T ss_dssp             GGHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHhh-CCCCCHHHHHHHHHHHHHhCCH----------------HHHHHHHHHccCCCchHHHHHHHHHHHHH
Confidence            34556666666 34  566777777776655421                12334455555556666666666666553


No 500
>4D50_A DEOXYHYPUSINE HYDROXYLASE (E.C.1.14.99.29); OXIDOREDUCTASE; HET: GAI; 1.7A {HOMO SAPIENS}
Probab=67.63  E-value=0.43  Score=42.31  Aligned_cols=60  Identities=10%  Similarity=0.123  Sum_probs=34.5  Template_Neff=12.700

Q NP_000290.2     547 DAIRTYLNLMGKSK--KDATLEACAGALQNLTASKGLMSSGMSQLIGLKEKGLPQIARLLQSGNSDVVRSGASLLSNMS  623 (747)
Q Consensus       547 G~I~~LL~LL~ss~--d~eVr~~AL~aL~nLs~~s~~~s~~~~~~llie~giI~~Ll~LL~s~d~eVr~~AL~aLsnLa  623 (747)
                      ..++.|...+. +.  ++.++..++.+|..+...                ..++.+...+.+.++.++..++.+|..+.
T Consensus        74 ~~~~~l~~~l~-~~~~~~~vr~~a~~~l~~~~~~----------------~~~~~l~~~l~~~~~~v~~~a~~~l~~~~  135 (294)
T 4D50_A           74 RAIPMLVDVLQ-DTRQEPMVRHEAGEALGAIGDP----------------EVLEILKQYSSDPVIEVAETCQLAVRRLE  135 (294)
T ss_dssp             GGHHHHHHHHH-CTTSCHHHHHHHHHHHHHHCCG----------------GGHHHHHHHTTCSSHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHhh-CCCCCHHHHHHHHHHHHHhCCH----------------HHHHHHHHHccCCCchHHHHHHHHHHHHH
Confidence            34556666666 34  566777777776655421                12334455555556666666666666553


Query         NP_000548.2
Match_columns 501
No_of_seqs    1691 out of 7065
Neff          7.55495
Searched_HMMs 400
Date          Sat Jul 25 00:10:29 2020
Command       /home/guerler/hh-suite/build/bin/hhblits -i /home/guerler/human/fasta/NP_00/NP_000548.2.fasta -d /home/guerler/pdb70/pdb70 -o /home/guerler/human/hhr/NP_00/NP_000548.2.hhr 

 No Hit                             Prob E-value P-value  Score    SS Cols Query HMM  Template HMM
  1 5FFO_H Integrin alpha-V, Integ 100.0 2.3E-42 2.1E-46  353.3   0.0  315  143-501    24-363 (363)
  2 3RJR_C Transforming growth fac 100.0 3.4E-42 3.1E-46  351.8   0.0  315  143-501    24-363 (363)
  3 5VQF_C Transforming growth fac 100.0 3.4E-42 3.2E-46  351.8   0.0  315  143-501    24-363 (363)
  4 5NTU_A Growth/differentiation  100.0 9.5E-42 8.8E-46  343.8   0.0  309  142-501    17-335 (335)
  5 5HLY_A Inhibin beta A chain; G 100.0   3E-39 2.7E-43  332.7   0.0  307  142-501    40-383 (383)
  6 6SF3_B Serine/threonine-protei  99.8 1.5E-26 1.3E-30  194.7   0.0  105  397-501     4-108 (108)
  7 4MPL_A Growth/differentiation   99.8 2.3E-26   2E-30  196.3   0.0  106  396-501    10-116 (116)
  8 6Z3J_B Growth/differentiation   99.8 2.6E-26 2.3E-30  196.2   0.0  107  395-501    11-117 (117)
  9 5I05_A Growth/differentiation   99.8   4E-26 3.5E-30  192.9   0.0  106  396-501     4-110 (110)
 10 4N1D_A Bone morphogenetic prot  99.8 4.5E-26 3.9E-30  194.5   0.0  106  396-501    11-116 (116)
 11 2QCQ_B Bone morphogenetic prot  99.8 5.7E-26   5E-30  191.9   0.0  105  397-501     5-110 (110)
 12 1LXI_A BONE MORPHOGENETIC PROT  99.8   9E-26 7.8E-30  198.7   0.0  111  391-501    29-139 (139)
 13 6OMN_G Bone morphogenetic prot  99.8 9.8E-26 8.7E-30  189.8   0.0  105  396-501     4-108 (108)
 14 2R53_A Bone morphogenetic prot  99.8 9.9E-26 8.7E-30  192.3   0.0  106  396-501    11-116 (116)
 15 2R53_B Bone morphogenetic prot  99.8 9.9E-26 8.7E-30  192.3   0.0  106  396-501    11-116 (116)
 16 1REU_A bone morphogenetic prot  99.8 1.1E-25   1E-29  187.7   0.0  102  399-501     2-103 (103)
 17 1M4U_L Bone Morphogenetic Prot  99.8 1.2E-25 1.1E-29  197.8   0.0  111  391-501    29-139 (139)
 18 2H62_B Bone morphogenetic prot  99.8 2.1E-25 1.9E-29  189.6   0.0  105  396-501    10-114 (114)
 19 6Q2J_B Growth/differentiation   99.8 3.8E-25 3.2E-29  193.7   0.0  102  396-501    34-135 (135)
 20 1KTZ_A TRANSFORMING GROWTH FAC  99.8 7.5E-25 6.6E-29  185.6   0.0  102  395-501    10-112 (112)
 21 5TY4_B TGF-beta receptor type-  99.8 9.9E-25 8.8E-29  179.9   0.0   96  400-500     1-97  (97)
 22 5VT2_B Growth/differentiation   99.8 1.1E-24 9.5E-29  184.6   0.0  102  396-501    11-112 (112)
 23 5VZ3_A Growth/differentiation   99.8 1.1E-24 9.5E-29  184.6   0.0  102  396-501    11-112 (112)
 24 2ARP_A Inhibin beta A chain, F  99.8 1.3E-24 1.2E-28  184.9   0.0  105  397-501     8-116 (116)
 25 2ARV_A Inhibin beta A chain; h  99.8 1.3E-24 1.2E-28  184.9   0.0  105  397-501     8-116 (116)
 26 2P6A_B Activin A, Follistatin   99.8 1.3E-24 1.2E-28  184.9   0.0  105  397-501     8-116 (116)
 27 2TGI_A TRANSFORMING GROWTH FAC  99.8 1.5E-24 1.3E-28  183.7   0.0  101  396-501    11-112 (112)
 28 3HH2_B Growth/differentiation   99.8 2.4E-24 2.1E-28  181.5   0.0   99  396-501    11-109 (109)
 29 5F3B_C RK35 Chimeric antibody   99.8 2.4E-24 2.1E-28  181.5   0.0   99  396-501    11-109 (109)
 30 3KFD_D Transforming growth fac  99.8 3.7E-24 3.2E-28  181.3   0.0  102  395-501    10-112 (112)
 31 5E4G_A Growth/differentiation   99.8 1.2E-23 1.1E-27  177.0   0.0   99  396-501    11-109 (109)
 32 5NMZ_B Neurturin; cystine knot  99.7 2.2E-22 1.9E-26  167.0   0.0   93  397-501     4-101 (101)
 33 5NMZ_C Neurturin; cystine knot  99.7 2.2E-22 1.9E-26  167.0   0.0   93  397-501     4-101 (101)
 34 2GH0_C artemin, GDNF family re  99.7 2.9E-22 2.6E-26  166.0   0.0   95  398-501     2-100 (101)
 35 5MR4_B Neurturin, GDNF family   99.7 4.4E-22 3.9E-26  165.4   0.0   94  396-501     4-102 (102)
 36 2V5E_B GDNF FAMILY RECEPTOR AL  99.7 7.4E-22 6.6E-26  163.6   0.0   93  397-501     5-101 (101)
 37 2ASK_B artemin; Glial cell der  99.7 9.1E-22   8E-26  166.6   0.0   94  396-501    12-112 (113)
 38 3FUB_D GDNF family receptor al  99.7 9.6E-22 8.1E-26  171.2   0.0   96  394-501    35-134 (134)
 39 1AGQ_C GLIAL CELL-DERIVED NEUR  99.7 2.2E-21 1.8E-25  169.0   0.0   95  395-501    37-135 (135)
 40 5TX2_A Transforming growth fac  99.7 2.9E-21 2.5E-25  157.7   0.0   81  396-501    12-93  (93)
 41 5TX4_B TGF-beta receptor type-  99.7   3E-21 2.6E-25  157.3   0.0   81  396-501    11-92  (92)
 42 2GYZ_A neurotrophic factor art  99.6 1.4E-19 1.2E-23  150.9   0.0   89  399-497     1-97  (105)
 43 6Q2S_B Ubiquitin-like protein   99.5 2.9E-18 2.5E-22  163.2   0.0   93  397-501   135-234 (235)
 44 6GFF_E Transforming growth fac  98.9 1.1E-13   1E-17  131.1   0.0  158  143-316    22-193 (249)
 45 6GFF_G Transforming growth fac  98.9 1.1E-13   1E-17  131.2   0.0  158  143-316    22-193 (249)
 46 5HLZ_E Inhibin beta A chain; G  98.7 1.8E-12 1.6E-16  124.5   0.0  155  143-317    41-227 (270)
 47 4YCG_B pro-BMP9 prodomain, hum  98.7 3.5E-12 3.2E-16  124.4   0.0  152  143-316    41-208 (296)
 48 4YCI_B mouse pro-BMP9 prodomai  98.7 3.5E-12 3.2E-16  124.4   0.0  152  143-316    41-208 (296)
 49 4NT5_A von Willebrand factor;   75.7    0.27 2.4E-05   38.0   0.0   65  422-501    37-101 (107)
 50 2KD3_A Sclerostin; Protein, an  73.5    0.35   3E-05   38.0   0.0   73  419-501    39-112 (113)
 51 4YU8_A Neuroblastoma suppresso  70.0    0.48 4.1E-05   38.5   0.0   88  398-501    32-120 (139)
 52 2K8P_A Sclerostin; WNT SIGNALL  66.7    0.66 5.3E-05   39.9   0.0   74  419-501    71-144 (189)
 53 4JPH_D Gremlin-2; Cystine knot  65.1    0.72   6E-05   37.9   0.0   88  398-501    51-138 (148)
 54 4X1J_B Neuroblastoma suppresso  64.2    0.74 6.5E-05   35.8   0.0   88  398-501    17-105 (116)
 55 5AEJ_A GREMLIN-1; SIGNALING PR  62.6    0.87 7.2E-05   37.6   0.0   87  397-501    59-147 (152)
 56 5HK5_G Gremlin-2, Growth/diffe  61.9    0.91 7.6E-05   37.2   0.0   86  398-501    50-137 (147)
 57 5BPU_A Frizzled-4; Wnt signall  57.8     1.2  0.0001   35.0   0.0   72  422-501    37-108 (122)
 58 5BQ8_C Norrin; Wnt signalling   54.0     1.5 0.00013   34.3   0.0   93  398-501    16-108 (122)
 59 5BQE_A Frizzled-4; Wnt signall  54.0     1.5 0.00013   34.3   0.0   93  398-501    16-108 (122)

No 1
>5FFO_H Integrin alpha-V, Integrin beta-6, Transforming; Integrin, TGF-beta, CELL ADHESION; HET: MAN, NAG, BMA; 3.49A {Homo sapiens}
Probab=100.00  E-value=2.3e-42  Score=353.27  Aligned_cols=315  Identities=24%  Similarity=0.379  Sum_probs=194.7  Template_Neff=9.300

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGG----N--SSVKLEAGLANTITSFIDKGQDDRG-P  215 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~----~--~~~~~~~~~~n~Vrsf~~~~~~~~~-~  215 (501)
                      .+||++|||+++|+.+..    .+.+++++|++||+.+........    .  ..+.+.....++++++......... .
T Consensus        24 ~~IL~~LgL~~~P~~~~~----~~~~~p~~m~~lY~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~s~~~~~~~~~~~~   99 (363)
T 5FFO_H           24 GQILSKLRLASPPSQGEV----PPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQ   99 (363)
T ss_dssp             HHHHHHTTCSSCCCSSSS----CSSCCCHHHHHHHHHHSCCCCC--------CCSSSSCEEEEEEECBCTTSSSTTTTCC
T ss_pred             HHHHHHcCCCCCCCCCCC----CCCCCCHHHHHHHHHHHhhccCCCCCCCCCCcccceeeeEEEEEEeecCccccccccc
Confidence            689999999999987642    223568999999998765431100    0  0011222234556666533221100 1


Q NP_000548.2     216 VVRKQRYVFDISA----LEK-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQPAALLDVRSVPGLDGSG  290 (501)
Q Consensus       216 ~~~~~~l~FnlSs----i~~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~~~~~ll~s~~v~~~~~~g  290 (501)
                      ......++|++++    ++. +.|.+|+||||+.....           ...|.||..... ....+++++.+.....++
T Consensus       100 ~~~~~~~~F~is~~~~~~~~~~~v~~AeLrl~~~~~~~-----------~~~v~iy~~~~~-~~~~~~~~~~~~~~~~~~  167 (363)
T 5FFO_H          100 STHSIYMFFQTSELREAVPEPVLLSRAELRLLRLKLKV-----------EQHVELYQKYSQ-NSWRYLSNRLLAPSDSPE  167 (363)
T ss_dssp             BTTEEEEEECSTTHHHHSCSGGGEEEEEEECCBCCCCS-----------CCEEEEEEEETT-TEEEEEEEEECCCCSSCC
T ss_pred             ccceEEEEEechhccccCCCchhhcHhhhHhhcCccCc-----------cEEEEEEEecCc-ccceeeEeEEeCCCCCCC
Confidence            2345678999997    433 57999999999887532           345677765421 111233333221234579


Q NP_000548.2     291 WEVFDIWKLFRNFKNSA--QLCLELEAWERG----RAVDLRGLGFDR------AARQVHEKALFLVFGRTKKRDLFFNEI  358 (501)
Q Consensus       291 Wv~fDVT~aV~~Wl~~~--nlgL~V~~~~~~----~~~~v~~~~~~~------~~~~~~~~ppLLv~~~~~~~~~~~~~~  358 (501)
                      |+.||||.+|+.|+.++  ++||.|.+....    ....+...++..      .......+|+|++++.+....      
T Consensus       168 W~~fdVt~~v~~W~~~~~~n~gl~v~v~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~P~Lv~~~~~~~~~------  241 (363)
T 5FFO_H          168 WLSFDVTGVVRQWLSRGGEIEGFRLSAHCSCDSRDNTLQVDINGFTTGRRGDLATIHGMNRPFLLLMATPLERA------  241 (363)
T ss_dssp             CCEEECHHHHHHHHHSCCSCEEEEEEECCBTTTTBCCCCCCBSCCTTTCCSSGGGGGGTTCCEEEEEECCTTTC------
T ss_pred             eEEEEcHHHHHHHHHcCCccccEEEEEEecCCCCCCceeeeeccccCCcccchhhccccCCcEEEEEeCchHHH------
Confidence            99999999999999997  788886554311    111110101100      011124566666666432210      


Q NP_000548.2     359 KARSGQDDKTVYEYLFSQRRKRRAPLATRQGKRPSKNLKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPL  437 (501)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~r~~rr~~~~~~~~~~~~~~~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~  437 (501)
                          .        ..+.+++ ||+.   + ...+.......||+++++|+|+ ||||+ |||+|++|+||||.|.|+++.
T Consensus       242 ----~--------~~~~~r~-rr~~---~-~~~~~~~~~~~Cc~~~l~V~F~~~lgw~-~iiaP~~~~a~~C~G~C~~~~  303 (363)
T 5FFO_H          242 ----Q--------HLQSSRH-RRAL---D-TNYCFSSTEKNCCVRQLYIDFRKDLGWK-WIHEPKGYHANFCLGPCPYIW  303 (363)
T ss_dssp             ----C-------------------------------CCSSSSEEECCCBCHHHHTCCC-SEEECCCBCCCEEECCCCCSC
T ss_pred             ----H--------hhhHHhh-Hhhc---c-cCCCCCCCcccceeeEEEEEccHHhCCc-eeeCCCeEEeeeccCCCCCcc
Confidence                0        0000111 1110   1 1122233467899999999996 99998 999999999999999999997


Q NP_000548.2     438 RSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       438 ~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..   +++|+.++++++...+..++.|||+|++|++|+|||+|++ .++++.++||+|++|||+
T Consensus       304 ~~---~t~ha~i~~~~~~~~~~~~~~~CC~P~~~~~l~ily~d~~-~~~~~~~~~m~v~~CgC~  363 (363)
T 5FFO_H          304 SL---DTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGR-KPKVEQLSNMIVRSCKCS  363 (363)
T ss_dssp             SC---C-----CCSSCTTTCSSCCSSCCEEECCEEEEEEEECC-C-CCEEEEEEEEEECCEEEC
T ss_pred             cc---cccHHHHHHHHHhhCCCCCCCCCcccceeceeeEEEEeCC-eeEEEEecCcEEeccCCC
Confidence            63   5688988888776555568999999999999999999987 588999999999999995


No 2
>3RJR_C Transforming growth factor beta-1; TGF beta, activation, integrin, Cytokine; HET: NAG; 3.05A {Sus scrofa}
Probab=100.00  E-value=3.4e-42  Score=351.82  Aligned_cols=315  Identities=24%  Similarity=0.389  Sum_probs=198.8  Template_Neff=9.400

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGG----NS--SVKLEAGLANTITSFIDKGQDDRG-P  215 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~----~~--~~~~~~~~~n~Vrsf~~~~~~~~~-~  215 (501)
                      .+||++|||+++|+....    .+.+++++|++||+.+........    ..  .+.+......+++++......... .
T Consensus        24 ~~IL~~LgL~~~P~~~~~----~~~~~p~~m~~lY~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~   99 (363)
T 3RJR_C           24 GQILSKLRLASPPSQGDV----PPGPLPEAVLALYNSTRDRVAGESVEPEPEPEADYYAKEVTRVLMVESGNQIYDKFKG   99 (363)
T ss_pred             HHHHHHcCCCCCCCCCCC----CCCCCCHHHHHHHHhhcccccCCcCCCCCCCcccccchhccceEeecCCcccccccCC
Confidence            689999999999987641    223568999999997654321100    00  001111122333333221110000 1


Q NP_000548.2     216 VVRKQRYVFDISAL----EK-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQPAALLDVRSVPGLDGSG  290 (501)
Q Consensus       216 ~~~~~~l~FnlSsi----~~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~~~~~ll~s~~v~~~~~~g  290 (501)
                      ......+.|+++++    +. +.|.+|+||||+.....           ...+.||..... ....++.++.+.....++
T Consensus       100 ~~~~~~~~F~~s~~~~~~~~~~~v~~AeL~l~~~~~~~-----------~~~v~iy~~~~~-~~~~~~~~~~~~~~~~~g  167 (363)
T 3RJR_C          100 TPHSLYMLFNTSELREAVPEPVLLSRAELRLLRLKLKV-----------EQHVELYQKYSQ-DSWRYLSNRLLAPSDSPE  167 (363)
T ss_pred             CccEEEEEEEcccCCCCCCcchhceEEEEEEEeCCCCC-----------CceEEEEEecCh-hheeEEEEEEeccCCCCc
Confidence            13466899999974    22 47999999999887542           235667754321 111233333221234579


Q NP_000548.2     291 WEVFDIWKLFRNFKNSA--QLCLELEAWER--G--RAVDLRGLGFDR------AARQVHEKALFLVFGRTKKRDLFFNEI  358 (501)
Q Consensus       291 Wv~fDVT~aV~~Wl~~~--nlgL~V~~~~~--~--~~~~v~~~~~~~------~~~~~~~~ppLLv~~~~~~~~~~~~~~  358 (501)
                      |+.|||+.+|+.|+.++  ++||.|.+...  .  ..+.+...++..      .......+|+|++++.+....      
T Consensus       168 W~~fdVt~~v~~W~~~~~~n~gl~l~v~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~P~Lv~~~~~~~~~------  241 (363)
T 3RJR_C          168 WLSFDVTGVVRQWLTRREAIEGFRLSAHCSCDSKDNTLHVEINGFNSGRRGDLATIHGMNRPFLLLMATPLERA------  241 (363)
T ss_pred             EEEEECHHHHHHHHhCCcccCcEEEEEEEccCCCCceeeEEEccccCCCcCCcccccccCCCEEEEEEcCCccc------
Confidence            99999999999999997  78888655321  1  111111001100      001124566666666432210      


Q NP_000548.2     359 KARSGQDDKTVYEYLFSQRRKRRAPLATRQGKRPSKNLKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPL  437 (501)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~r~~rr~~~~~~~~~~~~~~~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~  437 (501)
                                  ...+.++ +||+.   + ...+.......||+++++|+|+ ||||+ |||+|++|+||||.|.|+++.
T Consensus       242 ------------~~~~~~r-~rr~~---~-~~~~~~~~~~~Ccr~~l~V~F~~~lgW~-wIiaP~~y~a~~C~G~C~~~~  303 (363)
T 3RJR_C          242 ------------QHLHSSR-HRRAL---D-TNYCFSSTEKNCCVRQLYIDFRKDLGWK-WIHEPKGYHANFCLGPCPYIW  303 (363)
T ss_pred             ------------ccccccc-ccccC---C-CCCCCCCCCCcccceeEEEecchhhCCc-eEecCCeEEeeeecccCCCCC
Confidence                        0000011 11110   1 1122223467899999999997 99997 999999999999999999997


Q NP_000548.2     438 RSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       438 ~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..   .++|+.++++++...+..++.|||+|++|++|+|||+|++ ++++++++||+|++|||+
T Consensus       304 ~~---~t~ha~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~-~~~~~~~~~mvv~~CgC~  363 (363)
T 3RJR_C          304 SL---DTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGR-KPKVEQLSNMIVRSCKCS  363 (363)
T ss_pred             CC---cCcHHHHHHHHHhcCCCCCCCCcccccccCceEEEEEcCC-cEEEEEeCCeEEeeccCC
Confidence            63   5689999988876555578999999999999999999987 588999999999999995


No 3
>5VQF_C Transforming growth factor beta-1; pro-complex, latency, homodimer, PROTEIN BINDING; HET: NAG, BMA; 2.9A {Sus scrofa}
Probab=100.00  E-value=3.4e-42  Score=351.78  Aligned_cols=315  Identities=24%  Similarity=0.389  Sum_probs=197.2  Template_Neff=9.400

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGG----NS--SVKLEAGLANTITSFIDKGQDDRG-P  215 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~----~~--~~~~~~~~~n~Vrsf~~~~~~~~~-~  215 (501)
                      .+||++|||+++|++...    .+.+++++|++||+.+........    ..  .+.+.....++++++......... .
T Consensus        24 ~~IL~~LgL~~~P~~~~~----~~~~~p~~m~~lY~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~   99 (363)
T 5VQF_C           24 GQILSKLRLASPPSQGDV----PPGPLPEAVLALYNSTRDRVAGESVEPEPEPEADYYAKEVTRVLMVESGNQIYDKFKG   99 (363)
T ss_dssp             HHHHHHTTCSSCCCCTTC----CCSCCCHHHHHHHHHHHCCCBCC-------CCCCSSCEEEEEEECCCSSSSTTTSSTT
T ss_pred             HHHHHHcCCCCCCCCCCC----CCCCCCHHHHHHHHHHhhhcCCCCCCCCCCChhhheeeEEEEEEEeecCCceecccCC
Confidence            689999999999987641    223568999999997655421100    00  001111122333333221110000 1


Q NP_000548.2     216 VVRKQRYVFDISAL----EK-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQPAALLDVRSVPGLDGSG  290 (501)
Q Consensus       216 ~~~~~~l~FnlSsi----~~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~~~~~ll~s~~v~~~~~~g  290 (501)
                      ......+.|+++++    +. +.|.+|+||||+.....           ...+.||..... ....++.++.+.....++
T Consensus       100 ~~~~~~l~F~~s~~~~~~~~~~~v~~AeL~l~~~~~~~-----------~~~v~iy~~~~~-~~~~~~~~~~~~~~~~~g  167 (363)
T 5VQF_C          100 TPHSLYMLFNTSELREAVPEPVLLSRAELRLLRLKLKV-----------EQHVELYQKYSQ-DSWRYLSNRLLAPSDSPE  167 (363)
T ss_dssp             CTTEEEEEEEHHHHHHHCSSGGGEEEEEEEEEECCCSS-----------CEEEEEEEECSS-SCEEEEEEEEECCCSSCE
T ss_pred             CCCeEEEEEEhhhccccCCCccceeeeEEEEEEcCCcc-----------ceEEEEEEecCc-ccceeEEeEEeCCCCCCC
Confidence            13466899999974    22 47999999999887542           245667754321 111233333221234579


Q NP_000548.2     291 WEVFDIWKLFRNFKNSA--QLCLELEAWER--G--RAVDLRGLGFDR------AARQVHEKALFLVFGRTKKRDLFFNEI  358 (501)
Q Consensus       291 Wv~fDVT~aV~~Wl~~~--nlgL~V~~~~~--~--~~~~v~~~~~~~------~~~~~~~~ppLLv~~~~~~~~~~~~~~  358 (501)
                      |+.|||+.+|+.|+.++  +++|.|.+...  .  ..+.+...++..      .......+|+|++++.+....      
T Consensus       168 W~~fdvt~~v~~W~~~~~~n~gl~l~v~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~P~Lvi~~~~~~~~------  241 (363)
T 5VQF_C          168 WLSFDVTGVVRQWLTRREAIEGFRLSAHCSCDSKDNTLHVEINGFNSGRRGDLATIHGMNRPFLLLMATPLERA------  241 (363)
T ss_dssp             EEEEECHHHHHHHHHCCCSEEEEEEEECEEEEEETTEEEEEEC------CCCSBCCSSTTCCEEEEEECCSTTT------
T ss_pred             eEEEEcHHHHHHHHhhchhcCCEEEEEEeecCCCCCceeeEEccccCCCccchhhccccCCcEEEEEEChhHHh------
Confidence            99999999999999997  78888655321  1  111111001100      001124566666666432110      


Q NP_000548.2     359 KARSGQDDKTVYEYLFSQRRKRRAPLATRQGKRPSKNLKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPL  437 (501)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~r~~rr~~~~~~~~~~~~~~~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~  437 (501)
                                  ...+.++ +||+.   . ...+.......||+++++|+|+ ||||| |||+|++|+||||.|.|+++.
T Consensus       242 ------------~~~~~~r-~rr~~---~-~~~~~~~~~~~Ccr~~l~V~F~~~lgWd-wIiaP~~y~a~~C~G~C~~~~  303 (363)
T 5VQF_C          242 ------------QHLHSSR-HRRAL---D-TNYCFSSTEKNCCVRQLYIDFRKDLGWK-WIHEPKGYHANFCLGPCPYIW  303 (363)
T ss_dssp             ------------CC---------CE---E-HHHHTTSCCSSSEEECCEEETTTTTCCC-CEEECSEEECCEEECCCCCTT
T ss_pred             ------------hccchhh-hhhcc---C-cCccCCCCCccceeeEEEEEcchhhCCc-eeeCCCeEEeEeecCCCCCcC
Confidence                        0000011 11110   1 1122223467899999999997 99997 999999999999999999997


Q NP_000548.2     438 RSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       438 ~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..   .++|+.++++++...+..++.|||+|++|++|+|||+|++ +++++.++||+|++|||+
T Consensus       304 ~~---~t~ha~v~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~-~~~~~~~~~miv~~CgC~  363 (363)
T 5VQF_C          304 SL---DTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGR-KPKVEQLSNMIVRSCKCS  363 (363)
T ss_dssp             TS---CSCCHHHHTGGGGCCGGGSSSCCEEESSEEEEEEEEEETT-EEEEEEEEEEEECEEEEC
T ss_pred             Cc---cccHHHHHHHHHhcCCCCCCCCCccCcccceeeEEEEECC-eeEEEEecCcEEeccCCC
Confidence            63   5689999988876555578999999999999999999987 588999999999999995


No 4
>5NTU_A Growth/differentiation factor 8; growth factor, signalling protein, TGFbeta; HET: EDO; 2.58A {Homo sapiens}
Probab=100.00  E-value=9.5e-42  Score=343.78  Aligned_cols=309  Identities=22%  Similarity=0.402  Sum_probs=196.1  Template_Neff=9.900

Q NP_000548.2     142 SSFLLKKAREPGPPREPKEPFR-P-PPITPHEYMLSLYRTLSDADRKGGNSSVKLEAGLANTITSFIDKGQDDRGPVVRK  219 (501)
Q Consensus       142 ~~qIL~kLGL~~~P~~~~~~~~-~-~~~~~p~~MldLY~~~~~~~~~~~~~~~~~~~~~~n~Vrsf~~~~~~~~~~~~~~  219 (501)
                      -.+||++|||+++|++....++ . +..+++++|+++|+.+....... ...++++...+++|++|..............
T Consensus        17 k~~IL~~LgL~~~P~~~~~~~~~~~~~~~~~~~l~~~y~~~~~~~~~~-~~~~~~~~~~~~~v~~f~~~~~~~~~~~~~~   95 (335)
T 5NTU_A           17 KIQILSKLRLETAPNISKDVIRQLLPKAPPLRELIDQYDVQRDDSSDG-SLEDDDYHATTETIITMPTESDFLMQVDGKP   95 (335)
T ss_pred             HHHHHHHcCCCCCCCCCCCCCcccCCCCCchHHHHHHHhhccCCCCCC-CCcccchhcccceEEEeccCCCcccCCCCCC
Confidence            4689999999999998763110 0 11225799999999765432110 0011223345567888865432210001245


Q NP_000548.2     220 QRYVFDISALEK-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGR---QPAALLDVRSVP-GLDGSGWEVF  294 (501)
Q Consensus       220 ~~l~FnlSsi~~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~---~~~~ll~s~~v~-~~~~~gWv~f  294 (501)
                      ..++|+++++.. +.|.+|+||||+......         ....+.||......   .....+....+. ....++|++|
T Consensus        96 ~~~~F~ls~~~~~~~v~~AeL~l~~~~~~~~---------~~~~v~vy~v~~~~~~~~~~~~~~~~~~~~~~~~~gW~~f  166 (335)
T 5NTU_A           96 KCCFFKFSSKIQYNKVVKAQLWIYLRPVETP---------TTVFVQILRLIKPMKDGTRYTGIRSLKLDMNPGTGIWQSI  166 (335)
T ss_pred             eEEEEECCCCCCCcceeEEEEEEEECCCCCC---------CeEEEEEEEEEccCcCCceeeeeeEEEEEccCCCCcEEEE
Confidence            678999997654 589999999999875431         13456666543210   000011111111 1234699999


Q NP_000548.2     295 DIWKLFRNFKNSA--QLCLELEAWERG-RAVDLRGLGFDRAARQVHEKALFLVFGRTKKRDLFFNEIKARSGQDDKTVYE  371 (501)
Q Consensus       295 DVT~aV~~Wl~~~--nlgL~V~~~~~~-~~~~v~~~~~~~~~~~~~~~ppLLv~~~~~~~~~~~~~~~~~~~~~~~~~~~  371 (501)
                      |||.+|++|+.++  ++||.|.+...+ ....+   .+.... ....+|+|++++.+..                     
T Consensus       167 dVt~~v~~W~~~~~~n~gl~v~~~~~~~~~~~~---~~~~~~-~~~~~P~Lvi~~~~~~---------------------  221 (335)
T 5NTU_A          167 DVKTVLQNWLAAPASNLGIEIKALDENGHDLAV---TFPGPG-EDGLNPFLEVKVTDTP---------------------  221 (335)
T ss_pred             EcHHHHHHHHHCCccCceEEEEEEeCCCCeEee---ecCCCC-CcccCcEEEEEecCCC---------------------
Confidence            9999999999986  789988775432 11111   111111 1234555555542110                     


Q NP_000548.2     372 YLFSQRRKRRAPLATRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQT  451 (501)
Q Consensus       372 ~~~~~r~~rr~~~~~~~~~~~~~~~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~  451 (501)
                          .++ +|.    ....|........||+++++|+|+||||+ |||+|++|+||||.|.|+++....   ++|+.   
T Consensus       222 ----~~~-~r~----~~~~~~~~~~~~~Ccr~~l~V~F~~igW~-wIiaP~~y~a~~C~G~C~~~~~~~---~~~~~---  285 (335)
T 5NTU_A          222 ----KRS-RRD----FGLDCDEHSTESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFLAA---YPHTH---  285 (335)
T ss_pred             ----ccc-ccc----CCCCCCCCCCCCCceeeEEEEEHHHcCCc-eeecCCeEEeEeeCccCCCCcccc---CCCch---
Confidence                111 111    10123233357899999999999999998 999999999999999999998642   24442   


Q NP_000548.2     452 LMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       452 ~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +++...+...+.|||+|++|++|+|||+|++++++++.++||+|++|||+
T Consensus       286 ~~~~~~~~~~~~pCC~P~~~~~l~ily~~~~~~i~~~~~~~mvv~~CgC~  335 (335)
T 5NTU_A          286 LVHQANPRGSAGPCCTPTKMSPINMLYFNGKEQIIYGKIPAMVVDRCGCS  335 (335)
T ss_pred             hHhccCCCCCCCCcccceeccceEEEEECCCCCEEEEEeCCceeeccccC
Confidence            23333333578999999999999999999887889999999999999995


No 5
>5HLY_A Inhibin beta A chain; Growth factor, Precursor, Signalling, Signaling; HET: MSE; 2.302A {Homo sapiens}
Probab=100.00  E-value=3e-39  Score=332.69  Aligned_cols=307  Identities=21%  Similarity=0.407  Sum_probs=167.2  Template_Neff=8.800

Q NP_000548.2     142 SSFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKG------GN----SSVKLEAGLANTITSFIDKGQD  211 (501)
Q Consensus       142 ~~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~------~~----~~~~~~~~~~n~Vrsf~~~~~~  211 (501)
                      =.+||++|||+++|+++..    .  +.+..+..+|+.+.......      .+    .+.+.+...++.|+.|....  
T Consensus        40 K~~IL~kLgL~~~P~~~~~----~--p~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~t~~ii~f~~~~--  111 (383)
T 5HLY_A           40 KKHILNMLHLKKRPDVTQP----V--PKAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESG--  111 (383)
T ss_dssp             HHHHHHHTTCSSCCCCCCC----S--CHHHHHHHHHHTTSEEECGGGCEEETTCHHHHHHHHHHHHTEEEEEEECEEC--
T ss_pred             HHHHHHHcCCCCCCCCCCC----C--CCHHHHHHHHHhhcCCCCCCCcccccCCCCCCCCccccccceeEEEEECcCC--
Confidence            3689999999999998752    1  11222234565443211000      00    00112223456666665432  


Q NP_000548.2     212 DRGPVVRKQRYVFDISALE-K-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGR-----------------  272 (501)
Q Consensus       212 ~~~~~~~~~~l~FnlSsi~-~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~-----------------  272 (501)
                           .....++|++++.+ . +.|.+||||||+.......      ......|.||......                 
T Consensus       112 -----~~~~~l~F~iS~~~~~~~~V~~AeL~l~~~~~~~~~------~~~~~~V~vy~~~~~~~~~~~~~~~~~~~~~~~  180 (383)
T 5HLY_A          112 -----TARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANR------TRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKG  180 (383)
T ss_dssp             -----SSTTEEEEHCCE-------EEEEEEEEEEECS----------------------------------SC----CEC
T ss_pred             -----CCeEEEEEEcCCCCCCcceeEEEEEEEEecCCCCCC------CCceEEEEEEEEecCCCCCCCCcchhHhhcCCc
Confidence                 13567899999754 2 4699999999998764320      1124567777543210                 


Q NP_000548.2     273 -QPAALLDVRSVPGLDGSGWEVFDIWKLFRNFKNSA--QLCLELEAWERGR-AVDLRGLGFDRAARQVHEKALFLVFGRT  348 (501)
Q Consensus       273 -~~~~ll~s~~v~~~~~~gWv~fDVT~aV~~Wl~~~--nlgL~V~~~~~~~-~~~v~~~~~~~~~~~~~~~ppLLv~~~~  348 (501)
                       ....++.++.+ ....++|++||||.+|+.|+.++  +++|.|.+..... ...+   ...........+|+|++++.+
T Consensus       181 ~~~~~l~~s~~i-~~~~~gWi~fdVt~~V~~Wl~~~~~n~gl~v~~~~~~~~~~~l---~~~~~~~~~~~~P~Lvi~~~~  256 (383)
T 5HLY_A          181 ERSELLLSEKVV-DARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQCQESGASL---VLLGEEKEQSHRPFLMLQARQ  256 (383)
T ss_dssp             CEEEEEEEEEEE-ECSSCEEEEEECHHHHHHHHHTTCCEEEEEEECTTTTTTTCEE---ECSCCGGGGGGCCEEEEEEEC
T ss_pred             ccceEEEEEEEE-eCCCCcEEEEEcHHHHHHHHhCCccCcceEEEEEcCCCCCceE---EEecCCCccccccEEEEEEcC
Confidence             00112333333 23457999999999999999987  7888877653221 1101   000011112356666666532


Q NP_000548.2     349 KKRDLFFNEIKARSGQDDKTVYEYLFSQRRKRRAPLATRQGKRPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFH  428 (501)
Q Consensus       349 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~r~~rr~~~~~~~~~~~~~~~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~y  428 (501)
                      ...                      . +++++++    . ..|  ......||+++++|+|+||||++|||+|++|+|+|
T Consensus       257 ~~~----------------------~-~~rr~~~----~-~~~--~~~~~~Cc~~~~~V~F~~lgw~~wIiaP~~y~a~~  306 (383)
T 5HLY_A          257 SED----------------------H-PHRRRRR----G-LEC--DGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANY  306 (383)
T ss_dssp             C-------------------------------------C-CBC--SSCSSBCEEECCEEETTTTTCTTTEEECSEEECCE
T ss_pred             ccc----------------------c-ccccccc----C-CCC--CCCCcccccceeeecHHHhCCcceeecCCEEEcee
Confidence            110                      0 0111111    0 112  12468999999999999999988999999999999


Q NP_000548.2     429 CEGLCEFPLRSHLE--PTNHAVIQTLMNS--MDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       429 C~G~C~~~~~~~~~--~~~h~~i~~~~~~--~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |.|.|+.+.....+  .++|+.+...+..  ..+...+.|||+|++|++++|||+|++++++++.++||+|++|||+
T Consensus       307 C~G~C~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~pCC~P~~~~~l~ily~~~~~~i~~~~~~~mvv~~CgC~  383 (383)
T 5HLY_A          307 CEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS  383 (383)
T ss_dssp             EESBCC---------C---SCCC---------------CCCEEEEEEEEEEEEEES-SSCEEEEEEEEEEEEEEEEC
T ss_pred             ecccCCCCCCCCCCCcccHHHHHHHHHHhcCCCCCcCCCCcccccccCceEEEEEcCCCcEEEEEeCCcEEeecccC
Confidence            99999998653211  1235433332211  1123568999999999999999999987889999999999999995


No 6
>6SF3_B Serine/threonine-protein kinase receptor R3 (E.C.2.7.11.30); BMP10, ALK1, complex, signalling, TGFbeta; 2.3000067422A {Homo sapiens}
Probab=99.85  E-value=1.5e-26  Score=194.74  Aligned_cols=105  Identities=48%  Similarity=1.049  Sum_probs=89.1  Template_Neff=8.600

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISI  476 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~i  476 (501)
                      ...||+++++|+|+||||++|||+|++|+++||.|.|..+....++.++|+.++.+++...+.....|||+|++|++++|
T Consensus         4 ~~~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~t~h~~~~~~~~~~~~~~~~~~CC~P~~~~~l~i   83 (108)
T 6SF3_B            4 GNYCKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQKASKACCVPTKLEPISI   83 (108)
T ss_dssp             -CBSEEECCEEETTTTTGGGTEEECSEEECCEEESBBCSSCCGGGCCCHHHHHHHHHHHHCTTTSCCBCEEEEEEEEEEE
T ss_pred             CCcceEEEeEeeHHHhCCCceeeCCCceeceeeccccCCCCCCCCCCCchHHHHHHHHhhCccccCCCcccceecCceEE
Confidence            56899999999999999988999999999999999999987643334578877776654434467899999999999999


Q NP_000548.2     477 LFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       477 ly~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ||+++++.++.+.++||+|++|||+
T Consensus        84 l~~~~~~~~~~~~~~~~~v~~C~C~  108 (108)
T 6SF3_B           84 LYLDKGVVTYKFKYEGMAVSECGCR  108 (108)
T ss_dssp             EEEETTEEEEEEEEEEEEEEEEEEC
T ss_pred             EEEECCeeEEEEEECCeEEeecccC
Confidence            9999875555678999999999995


No 7
>4MPL_A Growth/differentiation factor 2; growth factor/cytokine, CYTOKINE; 1.9A {Homo sapiens}
Probab=99.84  E-value=2.3e-26  Score=196.32  Aligned_cols=106  Identities=50%  Similarity=1.028  Sum_probs=90.4  Template_Neff=7.900

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|+||||++|||+|++|+++||.|.|..+.....+.++|++++.+++...+.....|||+|++|++++
T Consensus        10 ~~~~C~~~~l~V~F~dlgw~~~Ii~P~~~~~~yC~G~C~~~~~~~~~~t~ha~i~~~~~~~~~~~~~~~CC~P~~~~~l~   89 (116)
T 4MPL_A           10 AGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPIS   89 (116)
T ss_dssp             CCCCCEEECCEEETTTTTCTTTEEECSEEECCEEESCCCSSCCTTCCCCHHHHHHHHHHHHSTTTSCCCCEEEEEEEEEE
T ss_pred             CCCCCEEEEEEEeHHHhCCCCCeeCCCeeEeEEEcccCCCCCCCCCCCCchHHHHHHHhhcCCccCCCCceeeeEecCeE
Confidence            35789999999999999998899999999999999999998765333457787777665443446789999999999999


Q NP_000548.2     476 ILFIDSANNVVYK-QYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~-~~~~mvv~~CgC~  501 (501)
                      |||+++++.++++ .++||+|++|+|+
T Consensus        90 ily~~~~~~~~~~~~~~~mvv~~CgC~  116 (116)
T 4MPL_A           90 VLYKDDMGVPTLKYHYEGMSVAECGCR  116 (116)
T ss_dssp             EEEECSSSCEEEEEEEEEEEEEEEEEC
T ss_pred             EEEECCCCcEEEEEEECCeEEeccccC
Confidence            9999988666666 8999999999995


No 8
>6Z3J_B Growth/differentiation factor 5, RGM domain; Repulsive Guidance Molecule, RGM, Bone; HET: SO4, GOL, NAG, EDO; 1.65A {Homo sapiens}
Probab=99.84  E-value=2.6e-26  Score=196.21  Aligned_cols=107  Identities=98%  Similarity=1.618  Sum_probs=92.0  Template_Neff=8.300

Q NP_000548.2     395 NLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPI  474 (501)
Q Consensus       395 ~~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l  474 (501)
                      .....||+++++|+|+||||++|||+|++|+++||.|.|..+.....+.++|+.++.+++...+.....|||+|++|+++
T Consensus        11 ~~~~~Cc~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~t~h~~i~~~~~~~~~~~~~~~cC~P~~~~~l   90 (117)
T 6Z3J_B           11 NLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPI   90 (117)
T ss_dssp             -CCCBSEEECCEEETTTTTGGGTEEECSEEECCEEESBCCSSCCGGGCCCHHHHHHHHHHHHCTTTSCCCCEEEEEEEEE
T ss_pred             CCCCcceeEEEEEeHHHcCCCccEEcCCeeeceeeeecCCCCccccCCCChHHHHHHHHHhcCCCCCCCCcccceeecce
Confidence            34789999999999999999889999999999999999999876433345788777766544445678999999999999


Q NP_000548.2     475 SILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       475 ~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +|+|+++++.++++.++||+|++|||+
T Consensus        91 ~ily~~~~~~~~~~~~~~~~v~~CgC~  117 (117)
T 6Z3J_B           91 SILFIDSANNVVKKDYEDMVVESCGCR  117 (117)
T ss_dssp             EEEEECTTSCEEEEEEEEEEEEEEEEC
T ss_pred             EEEEEcCCCcEEEEEECCeEEeeccCC
Confidence            999999877788999999999999995


No 9
>5I05_A Growth/differentiation factor 2; GROWTH DIFFERENTIATION FACTOR 2, CELL; HET: GOL; 1.87A {Homo sapiens}
Probab=99.84  E-value=4e-26  Score=192.88  Aligned_cols=106  Identities=50%  Similarity=1.028  Sum_probs=90.1  Template_Neff=8.400

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|+||||++|||+|++|+++||.|.|..+....++.++|+.++.+++...+.....|||+|++|++++
T Consensus         4 ~~~~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~~CC~P~~~~~l~   83 (110)
T 5I05_A            4 AGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPIS   83 (110)
T ss_dssp             CCCBSEEECCEEETTTTTCTTTEEECSEEECCEEESBCCSSCCGGGCCCHHHHHHHHHHHHCTTTSCCCCEEEEEEEEEE
T ss_pred             CCCcceeEEEEEeHHHhCCCCcEeCCCccccEeecCCCCCCCCCCCCCChhHHHHHHHhhcCCCCCCCcccceeeecceE
Confidence            35789999999999999998899999999999999999998764333457777776655443456789999999999999


Q NP_000548.2     476 ILFIDSANNVVYK-QYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~-~~~~mvv~~CgC~  501 (501)
                      |||+|++++++++ .++||+|++|||+
T Consensus        84 il~~~~~~~~~~~~~~~dm~v~~CgC~  110 (110)
T 5I05_A           84 VLYKDDMGVPTLKYHYEGMSVAECGCR  110 (110)
T ss_dssp             EEEECTTSCEEEEEEEEEEEEEEEEEC
T ss_pred             EEEECCCCcEEEEEEeCCeEEeecccC
Confidence            9999998766666 8999999999995


No 10
>4N1D_A Bone morphogenetic protein 2; Cytokine, Signaling Protein; 1.912A {Homo sapiens}
Probab=99.84  E-value=4.5e-26  Score=194.45  Aligned_cols=106  Identities=52%  Similarity=1.077  Sum_probs=90.5  Template_Neff=8.300

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|+||||++|||+|++|+++||.|.|..+.....+.++|+.++.+++...+.....|||+|++|++++
T Consensus        11 ~~~~Cc~~~~~v~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~t~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~   90 (116)
T 4N1D_A           11 LKSSCKRHPLYVDFNLIGWGSWIIYPKQYNAYRCEGECPNPVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCVPTELSAIS   90 (116)
T ss_dssp             -C-BSEEECCEEETTTTTCTTTEEECSEEECCEEESBCCSSCCGGGCCCHHHHHHHHHHHHCTTTSCCCCEEEEEEEEEE
T ss_pred             CCCcceeEEEEEEHHHhCCCCCEeCCCeeeceeeeEeCCCCCccCCCCChhHHHHHHHHhcCCCCCCCCceecceecceE
Confidence            46789999999999999998899999999999999999988764333457887777765444446789999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|+++++.++++.++||+|.+|||+
T Consensus        91 il~~~~~~~~~~~~~~~~~v~~C~C~  116 (116)
T 4N1D_A           91 MLYLDENEKVVLKNYQDMVVEGCGCR  116 (116)
T ss_dssp             EEEECTTCCEEEEEEEEEEEEEEEEC
T ss_pred             EEEECCCCcEEEEEeCCeEEeccccC
Confidence            99999877788999999999999995


No 11
>2QCQ_B Bone morphogenetic protein 3; BMP, TGF-beta, SIGNALING PROTEIN; 2.21A {Homo sapiens}
Probab=99.83  E-value=5.7e-26  Score=191.87  Aligned_cols=105  Identities=46%  Similarity=1.054  Sum_probs=89.3  Template_Neff=8.500

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMD-PESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~-~~~~~~pCC~P~~~~~l~  475 (501)
                      ...||+++++|+|+||||++|||+|++|+++||.|+|..+.....+.++|+.++.+++... ......|||+|++|++++
T Consensus         5 ~~~Cc~~~~~v~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~~~CC~P~~~~~l~   84 (110)
T 2QCQ_B            5 PRNCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGVVPGIPEPCCVPEKMSSLS   84 (110)
T ss_dssp             CSBSEEECCEEEGGGTTCTTTEEECSEEECCEEECBCCSSCCGGGCCCHHHHHHHHHHHSSCSTTCCCCCEEESSEEEEE
T ss_pred             CCcceeeEEEEeHHHhCCCcceeCCCeecceeeceeCCCCCCccCCCCcHHHHHHHHHHhCCCCCCCCCceeeEEeCceE
Confidence            4689999999999999998899999999999999999998754333457777777655332 134679999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |||++++++++++.++||+|++|||+
T Consensus        85 il~~~~~~~~~~~~l~~~~v~~CgC~  110 (110)
T 2QCQ_B           85 ILFFDENKNVVLKVYPNMTVESCACR  110 (110)
T ss_dssp             EEEECTTCCEEEEEEEEEEECCEEEC
T ss_pred             EEEEcCCCcEEEEEECCeEEeccccC
Confidence            99999887788899999999999995


No 12
>1LXI_A BONE MORPHOGENETIC PROTEIN 7; Cystine-knot growth factor, HORMONE-GROWTH FACTOR; HET: NAG; 2.0A {Homo sapiens} SCOP: g.17.1.2
Probab=99.83  E-value=9e-26  Score=198.70  Aligned_cols=111  Identities=48%  Similarity=1.063  Sum_probs=90.2  Template_Neff=7.500

Q NP_000548.2     391 RPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTR  470 (501)
Q Consensus       391 ~~~~~~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~  470 (501)
                      +........||+++++|+|++|||++|||+|++|+++||.|.|..+.....+.++|++++.+++...+.....|||+|++
T Consensus        29 ~~~~~~~~~C~~~~~~V~f~~igw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~t~h~~i~~l~~~~~~~~~~~~CC~P~~  108 (139)
T 1LXI_A           29 NSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQ  108 (139)
T ss_dssp             -------CBSEEECCEEEHHHHTCTTTEEECSEEECCEEESBCCSSCCGGGCCCHHHHHHHHHHHHCTTTCCCCCEEEEE
T ss_pred             cCCccccccceeeeeeccHHHhCCCCceecCCceeeeEecccCCCCcccccCCCHHHHHHHHHHhhCCCCCCCCceeeee
Confidence            33445678999999999999999988999999999999999999887543234577777776654434467899999999


Q NP_000548.2     471 LSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       471 ~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |++++|||+++++.++++.++||+|++|||+
T Consensus       109 ~~~l~ily~d~~~~i~~~~l~~mvv~~CgC~  139 (139)
T 1LXI_A          109 LNAISVLYFDDSSNVILKKYRNMVVRACGCH  139 (139)
T ss_dssp             EEEEEEEEECTTSCEEEEEEEEEEEEEEEEC
T ss_pred             eCceEEEEECCCCCEEEEEEcCeEEecccCC
Confidence            9999999999877788999999999999995


No 13
>6OMN_G Bone morphogenetic protein 2; BMP, Bone Mophogenetic Protein, CYTOKINE; HET: BMA, MAN, NAG; 2.68A {Homo sapiens}
Probab=99.83  E-value=9.8e-26  Score=189.80  Aligned_cols=105  Identities=57%  Similarity=1.165  Sum_probs=89.4  Template_Neff=8.400

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|+||||++|||+|++|+++||.|.|..+.....+.++|+.++.+++... ...+.|||+|++|++++
T Consensus         4 ~~~~Cc~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~h~~~~~~~~~~~-~~~~~~CC~P~~~~~l~   82 (108)
T 6OMN_G            4 LKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN-SKIPKACCVPTELSAIS   82 (108)
T ss_pred             CCCCcEEEEeEEehHHcCCCccEECCCeeeeEEEcccCCCCCccccCCCchHHHHHHHhcCC-CCCCCCceeEEeeCceE
Confidence            35789999999999999998899999999999999999988654333456777776654432 35689999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |||+++++.++++.++||+|++|||+
T Consensus        83 ily~~~~~~~~~~~~~~m~v~~CgC~  108 (108)
T 6OMN_G           83 MLYLDENEKVVLKNYQDMVVEGCGCR  108 (108)
T ss_pred             EEEECCCCcEEEEEeCCeEEeccccC
Confidence            99999877788999999999999995


No 14
>2R53_A Bone morphogenetic protein 6; BMP6, Vgr, TGF-beta ligand, Chondrogenesis; HET: MPD; 2.1A {Homo sapiens}
Probab=99.83  E-value=9.9e-26  Score=192.30  Aligned_cols=106  Identities=49%  Similarity=1.068  Sum_probs=89.6  Template_Neff=8.200

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|+||||++|||+|++|+++||.|.|..+.....+.++|+.++.+++.........|||+|++|++++
T Consensus        11 ~~~~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~h~~~~~~~~~~~~~~~~~~CC~P~~~~~l~   90 (116)
T 2R53_A           11 RLKACRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNAIS   90 (116)
T ss_dssp             CSSBSEEECCEEEGGGTTCTTTEEECSEEECCEEECBCCSSCCTTTTSCHHHHHHHHHHHHCTTTSCCCCEEEEEEEEEE
T ss_pred             ccCceEEEEEEEeHHHhCCCCcEecCCeEEeEEeceeCCCCCccccCCChHHHHHHHHHhcCCccCCCCeeeeeecCCeE
Confidence            36799999999999999998799999999999999999998654323456777666554433345789999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|+++++.+++++++||+|++|||.
T Consensus        91 il~~~~~~~~~~~~l~~~~v~~C~C~  116 (116)
T 2R53_A           91 VLYFDDNSNVILKKYRNMVVRACGCH  116 (116)
T ss_dssp             EEEECTTCCEEEEEEEEEEEEEEEEC
T ss_pred             EEEECCCCcEEEEEEcCeEEecccCC
Confidence            99999877788899999999999995


No 15
>2R53_B Bone morphogenetic protein 6; BMP6, Vgr, TGF-beta ligand, Chondrogenesis; HET: MPD; 2.1A {Homo sapiens}
Probab=99.83  E-value=9.9e-26  Score=192.30  Aligned_cols=106  Identities=49%  Similarity=1.068  Sum_probs=89.6  Template_Neff=8.200

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|+||||++|||+|++|+++||.|.|..+.....+.++|+.++.+++.........|||+|++|++++
T Consensus        11 ~~~~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~h~~~~~~~~~~~~~~~~~~CC~P~~~~~l~   90 (116)
T 2R53_B           11 RLKACRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPEYVPKPCCAPTKLNAIS   90 (116)
T ss_dssp             CSSBSEEECCEEEHHHHTCTTTEEECSEEECCEEESBCCSSCCGGGCCCHHHHHHHHHHHHCTTTSCCCCEEEEEEEEEE
T ss_pred             ccCceEEEEEEEeHHHhCCCCcEecCCeEEeEEeceeCCCCCccccCCChHHHHHHHHHhcCCccCCCCeeeeeecCCeE
Confidence            36799999999999999998799999999999999999998654323456777666554433345789999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|+++++.+++++++||+|++|||.
T Consensus        91 il~~~~~~~~~~~~l~~~~v~~C~C~  116 (116)
T 2R53_B           91 VLYFDDNSNVILKKYRNMVVRACGCH  116 (116)
T ss_dssp             EEEECTTSCEEEEEEEEEEEEEEEEC
T ss_pred             EEEECCCCcEEEEEEcCeEEecccCC
Confidence            99999877788899999999999995


No 16
>1REU_A bone morphogenetic protein 2; TGF-beta fold, HORMONE-GROWTH FACTOR COMPLEX; HET: MPD; 2.65A {Homo sapiens} SCOP: g.17.1.2
Probab=99.83  E-value=1.1e-25  Score=187.67  Aligned_cols=102  Identities=56%  Similarity=1.151  Sum_probs=87.5  Template_Neff=8.600

Q NP_000548.2     399 RCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILF  478 (501)
Q Consensus       399 ~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily  478 (501)
                      .||+++++|+|+||||++|||+|++|+++||.|.|..+.....+.++|+.++.+++... ...+.|||+|++|++++|||
T Consensus         2 ~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~~~~i~~~~~~~~-~~~~~~cC~P~~~~~l~ily   80 (103)
T 1REU_A            2 SCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPPADHLNSTNHAIVQTLVNSVN-SKIPKACCVPTELSAISMLY   80 (103)
T ss_dssp             BSEEECCEEETTTTTCTTTCCBCSEEECCEEECBCCSSCCSSSCBCHHHHHHHHHHHHC-SSSCCCCEEEEEEEEEEEEE
T ss_pred             CceEEEeEecHHHcCCCCcEeCCCeecceEEeeeCCCCCcccCCCChhHHHHHHHhhcC-CCCCCccceeeEeCceEEEE
Confidence            69999999999999998899999999999999999998754333456777776654332 35689999999999999999


Q NP_000548.2     479 IDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       479 ~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ++++++++++.++||+|++|||+
T Consensus        81 ~~~~~~~~~~~~~~~~v~~CgC~  103 (103)
T 1REU_A           81 LDENEKVVLKNYQDMVVEGCGCR  103 (103)
T ss_dssp             ECTTCCEEEEEEEEEEEEEEEEC
T ss_pred             EcCCCcEEEEEeCCeEEeccccC
Confidence            99877788999999999999995


No 17
>1M4U_L Bone Morphogenetic Protein-7/Noggin; NOGGIN, BMP ANTAGONIST, BMP-7, BONE; HET: NAG; 2.42A {Homo sapiens} SCOP: g.17.1.2
Probab=99.82  E-value=1.2e-25  Score=197.81  Aligned_cols=111  Identities=48%  Similarity=1.063  Sum_probs=88.2  Template_Neff=7.500

Q NP_000548.2     391 RPSKNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTR  470 (501)
Q Consensus       391 ~~~~~~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~  470 (501)
                      +........||+++++|+|++|||++|||+|++|+++||.|.|..+.....+.++|++++.+++...+.....|||+|++
T Consensus        29 ~~~~~~~~~C~~~~~~V~f~~igw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~t~h~~l~~l~~~~~~~~~~~pCC~P~~  108 (139)
T 1M4U_L           29 NSSSDQRQACKKHELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVPKPCCAPTQ  108 (139)
T ss_dssp             ---------SEEECCEEESGGGTCTTTEEECSEEECCEEECBCCSSEEGGGCCCHHHHHHHHHHHHCTTSSCCCCEEEEE
T ss_pred             ccCCCCCCcccceecccCHHHhCCCCceecCCeecceeecccCCCCCccccCCCHHHHHHHHHHhcCCCCCCCCceeeee
Confidence            33445678999999999999999988999999999999999999887533234577777776654434467899999999


Q NP_000548.2     471 LSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       471 ~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |++++|||+++++.++++.++||+|++|||+
T Consensus       109 ~~~l~ily~d~~~~i~~~~l~~mvv~~CgC~  139 (139)
T 1M4U_L          109 LNAISVLYFDDSSNVILKKYRNMVVRACGCH  139 (139)
T ss_dssp             EEEEEEEEECTTSCEEEEEEEEEEEEEEEES
T ss_pred             cCCeEEEEECCCCCEEEEEECCeEEeccccC
Confidence            9999999999877788999999999999995


No 18
>2H62_B Bone morphogenetic protein 2, Bone; TGF-beta superfamily, ligand-receptor complex, HORMONE-GROWTH; 1.85A {Homo sapiens} SCOP: g.17.1.2
Probab=99.82  E-value=2.1e-25  Score=189.59  Aligned_cols=105  Identities=57%  Similarity=1.165  Sum_probs=88.7  Template_Neff=8.300

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|++|||++|||+|++|+++||.|.|..+.....+.++|+.++.+++... .....|||+|++|++++
T Consensus        10 ~~~~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~t~h~~~~~~~~~~~-~~~~~~CC~P~~~~~l~   88 (114)
T 2H62_B           10 LKSSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLNSTNHAIVQTLVNSVN-SKIPKACCVPTELSAIS   88 (114)
T ss_dssp             --CBSEEECCEEEGGGTTCTTTEEECSEEECCEEECBCCSSCCGGGCCCHHHHHHHHHHHHC-TTSCCCCEEEEEEEEEE
T ss_pred             ccCcceEEEEEEehHHcCCCCcEeCCCeeeceEEeeeCCCCCccccCCCchHHHHHHHHhcC-CCCCCccceeeEeCceE
Confidence            46789999999999999998899999999999999999988754333456777776654332 35689999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|+|++++++++.++||+|++|+|+
T Consensus        89 ily~~~~~~~~~~~~~~~~v~~C~C~  114 (114)
T 2H62_B           89 MLYLDENEKVVLKNYQDMVVEGCGCR  114 (114)
T ss_dssp             EEEEETTTEEEEEEEEEEEEEEEEEC
T ss_pred             EEEECCCCcEEEEEeCCeEEeccccC
Confidence            99999877788999999999999995


No 19
>6Q2J_B Growth/differentiation factor 15, GDNF family; RET, receptor tyrosine kinase, cryo-EM; HET: NAG; 4.1A {Homo sapiens}
Probab=99.81  E-value=3.8e-25  Score=193.68  Aligned_cols=102  Identities=27%  Similarity=0.754  Sum_probs=85.9  Template_Neff=7.400

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....|++++++|+|+||||++|||+|++|+++||.|.|..+...   .++|+.++.+++...+..+..|||+|++|++++
T Consensus        34 ~~~cC~~~~~~V~F~dlGw~~wIi~P~~~~~~~C~G~C~~~~~~---~t~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  110 (135)
T 6Q2J_B           34 PGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRA---ANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMV  110 (135)
T ss_pred             CcCcceeEEEEEeHHHcCCCCcEECCCeEEeEEecccCCCCCCC---CChHHHHHHHHHhcCCCCCCCCceeeeeecceE
Confidence            34445458999999999997799999999999999999988753   346777777665444456789999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|++++ .++++.++||+|++|||+
T Consensus       111 ily~~~~-~i~~~~l~dmvv~~CgC~  135 (135)
T 6Q2J_B          111 LIQKTDT-GVSLQTYDDLLAKDCHCI  135 (135)
T ss_pred             EEEECCC-eEEEEEECCeEEeccccC
Confidence            9998874 788899999999999995


No 20
>1KTZ_A TRANSFORMING GROWTH FACTOR BETA 3/TGF-beta; CYTOKINE-RECEPTOR COMPLEX, CYTOKINE-CYTOKINE RECEPTOR COMPLEX; 2.15A {Homo sapiens} SCOP: g.17.1.2
Probab=99.80  E-value=7.5e-25  Score=185.60  Aligned_cols=102  Identities=35%  Similarity=0.837  Sum_probs=76.2  Template_Neff=8.200

Q NP_000548.2     395 NLKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSP  473 (501)
Q Consensus       395 ~~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~  473 (501)
                      .....||+++++|+|+ +|||+ |||+|++|+++||.|.|..+...   .++|+.++.+++...+...+.|||+|++|++
T Consensus        10 ~~~~~Cc~~~~~V~f~~~lgw~-~Ii~P~~~~~~~C~G~C~~~~~~---~~~h~~~~~~~~~~~~~~~~~~CC~P~~~~~   85 (112)
T 1KTZ_A           10 NLEENCCVRPLYIDFRQDLGWK-WVHEPKGYYANFCSGPCPYLRSA---DTTHSTVLGLYNTLNPEASASPCCVPQDLEP   85 (112)
T ss_dssp             ---CCCEEECCEEECCCCCCCC-CEEECSEEECCEEECCCCSSCCC---------------------CCCCCEEECCEEE
T ss_pred             cccCCcEEEEEEEECchhcCCC-eeeCCCeeeeeeeeecCCCCCCC---CCChHHHHHHHHhcCcccCCCCcccceecCc
Confidence            3478999999999999 99998 99999999999999999998753   3578877776654444567899999999999


Q NP_000548.2     474 ISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       474 l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ++|||++++ .++++.++||+|++|||+
T Consensus        86 l~ily~~~~-~~~~~~~~~miv~~CgC~  112 (112)
T 1KTZ_A           86 LTILYYVGR-TPKVEQLSNMVVKSCKCS  112 (112)
T ss_dssp             EEEEEEETT-EEEEEEEEEEEECCEEEC
T ss_pred             eEEEEEeCC-eeEEEEecCeEEeeCcCC
Confidence            999999987 577899999999999995


No 21
>5TY4_B TGF-beta receptor type-2 (E.C. 2.7.11.30); TRANSFERASE; 2.9A {Homo sapiens}
Probab=99.80  E-value=9.9e-25  Score=179.89  Aligned_cols=96  Identities=34%  Similarity=0.853  Sum_probs=84.4  Template_Neff=8.500

Q NP_000548.2     400 CSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILF  478 (501)
Q Consensus       400 Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily  478 (501)
                      ||+++++|+|+ ++||+ |||+|++|+++||.|.|..+...   .++|+.++.+++...+.....|||+|++|++++|+|
T Consensus         1 Cc~~~~~v~f~~~lgw~-~Ii~P~~~~~~~C~G~C~~~~~~---~~~h~~i~~~~~~~~~~~~~~~CC~P~~~~~l~il~   76 (97)
T 5TY4_B            1 CCLRPLYIDFRKDLGWK-WIHEPKGYNANFCAGACPYLWSS---DTQHSRVLSLYNTINPEASASPCCVSQDLEPLTIVY   76 (97)
T ss_pred             CeEEEEEEECccccCCC-ceeCCCcccCeeeceeCCCCCCC---CccHHHHHHHHHhcCcccCCCCceeceeccceeEEE
Confidence            89999999997 99998 99999999999999999988653   457888777765444445789999999999999999


Q NP_000548.2     479 IDSANNVVYKQYEDMVVESCGC  500 (501)
Q Consensus       479 ~d~~~~~~~~~~~~mvv~~CgC  500 (501)
                      ++++ +++++.++||+|++|||
T Consensus        77 ~~~~-~~~~~~~~~m~v~~CgC   97 (97)
T 5TY4_B           77 YVGR-KPKVEQLSNMIVKSCKC   97 (97)
T ss_pred             EeCC-ceEEEEecCeEEeeCCC
Confidence            9987 57889999999999999


No 22
>5VT2_B Growth/differentiation factor 15; TGF-beta family, SIGNALING PROTEIN; HET: EDO; 2.3A {Homo sapiens}
Probab=99.80  E-value=1.1e-24  Score=184.58  Aligned_cols=102  Identities=27%  Similarity=0.753  Sum_probs=87.2  Template_Neff=8.300

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....|++++++|+|+||||++|||+|++|+++||.|.|..+...   .++|+.++.+++...+.....|||+|++|++++
T Consensus        11 ~~~~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~---~~~h~~i~~~~~~~~~~~~~~~CC~P~~~~~l~   87 (112)
T 5VT2_B           11 PGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRA---ANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMV   87 (112)
T ss_dssp             TTCBSEEEEEEEEHHHHTCTTTEEECSEEEEEEEESBCCTTSSB---CSHHHHHHHHHHHHCTTTSCCCCEEEEEEEEEE
T ss_pred             CCCcceEEEEEEeHHHhCCCccEECCCeeeceeeeeeCCCCCCc---ccchHHHHHHHHhcCCCCCCCCceecceecceE
Confidence            34455569999999999998899999999999999999998753   457888877765544556789999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|+++ +.+++++++||+|++|||.
T Consensus        88 il~~~~-~~~~~~~~~~m~v~~C~C~  112 (112)
T 5VT2_B           88 LIQKTD-TGVSLQTYDDLLAKDCHCI  112 (112)
T ss_dssp             EEEECS-SSEEEEEEEEEEEEEEEEC
T ss_pred             EEEEcC-CeEEEEEeCCeEEecCCcC
Confidence            999887 4788999999999999995


No 23
>5VZ3_A Growth/differentiation factor 15; Growth Factor, SIGNALING PROTEIN; 1.97A {Homo sapiens}
Probab=99.80  E-value=1.1e-24  Score=184.58  Aligned_cols=102  Identities=27%  Similarity=0.753  Sum_probs=87.2  Template_Neff=8.300

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....|++++++|+|+||||++|||+|++|+++||.|.|..+...   .++|+.++.+++...+.....|||+|++|++++
T Consensus        11 ~~~~C~~~~~~V~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~---~~~h~~i~~~~~~~~~~~~~~~CC~P~~~~~l~   87 (112)
T 5VZ3_A           11 PGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRA---ANMHAQIKTSLHRLKPDTVPAPCCVPASYNPMV   87 (112)
T ss_dssp             SSSBSEEEEEEEEHHHHTCTTTEEECSEEEEEEEESBCCTTSSB---CSHHHHHHHHHHHHCTTTSCCCCEEEEEEEEEE
T ss_pred             CCCcceEEEEEEeHHHhCCCccEECCCeeeceeeeeeCCCCCCc---ccchHHHHHHHHhcCCCCCCCCceecceecceE
Confidence            34455569999999999998899999999999999999998753   457888877765544556789999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|+++ +.+++++++||+|++|||.
T Consensus        88 il~~~~-~~~~~~~~~~m~v~~C~C~  112 (112)
T 5VZ3_A           88 LIQKTD-TGVSLQTYDDLLAKDCHCI  112 (112)
T ss_dssp             EEEECS-SSEEEEEEEEEEEEEEEEC
T ss_pred             EEEEcC-CeEEEEEeCCeEEecCCcC
Confidence            999887 4788999999999999995


No 24
>2ARP_A Inhibin beta A chain, Follistatin; cystine knot, disulfide rich, egf; HET: GOL, 1PG; 2.0A {Homo sapiens} SCOP: g.17.1.2
Probab=99.79  E-value=1.3e-24  Score=184.92  Aligned_cols=105  Identities=38%  Similarity=0.831  Sum_probs=81.5  Template_Neff=8.700

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHL--EPTNHAVIQTLMNS--MDPESTPPTCCVPTRLS  472 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~--~~~~h~~i~~~~~~--~~~~~~~~pCC~P~~~~  472 (501)
                      ...||++.++|+|++|||++|||+|++|+++||.|.|..+.....  ..++|+.++.++..  ..+.....|||+|++|+
T Consensus         8 ~~~C~~~~~~v~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~~~h~~~~~~~~~~~~~~~~~~~~CC~P~~~~   87 (116)
T 2ARP_A            8 VNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLR   87 (116)
T ss_dssp             -CCSEEECCEEEHHHHTCTTTEEECSEEECCEEESCCCC-CCHHH----H----HHHHTTSTTCSSCCCCCCCEEEEEEE
T ss_pred             cccceeEEEEEeHHHcCCccceeCCCceeCceeeeeCCCCcCcCCCCCcchHHHHHHHHHhhCCCCCcCCCCcccccccC
Confidence            678999999999999999889999999999999999998865321  12456655554321  12335679999999999


Q NP_000548.2     473 PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       473 ~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +++|+|++++++++++.++||+|++|||+
T Consensus        88 ~l~il~~~~~~~~~~~~~~~m~v~~CgC~  116 (116)
T 2ARP_A           88 PMSMLYYDDGQNIIKKDIQNMIVEECGCS  116 (116)
T ss_dssp             EEEEEEEC-TTCEEEEEEEEEEEEEEEEC
T ss_pred             ceEEEEEcCCCcEEEEEeCCeEEeecccC
Confidence            99999999877788999999999999995


No 25
>2ARV_A Inhibin beta A chain; homodimer, cystine knot, disulfide linked; HET: 1PG, SO4, GOL; 2.0A {Homo sapiens} SCOP: g.17.1.2
Probab=99.79  E-value=1.3e-24  Score=184.92  Aligned_cols=105  Identities=38%  Similarity=0.831  Sum_probs=86.7  Template_Neff=8.700

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHL--EPTNHAVIQTLMNS--MDPESTPPTCCVPTRLS  472 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~--~~~~h~~i~~~~~~--~~~~~~~~pCC~P~~~~  472 (501)
                      ...||++.++|+|++|||++|||+|++|+++||.|.|+.+.....  +.++|+.++.++..  ..+.....|||+|++|+
T Consensus         8 ~~~C~~~~~~v~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~~~h~~~~~~~~~~~~~~~~~~~~CC~P~~~~   87 (116)
T 2ARV_A            8 VNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLR   87 (116)
T ss_dssp             CCBSEEECCEEETTTTTCTTTEEECSEEECCEEESBCCGGGTTEETTEECHHHHHHHHHHHTTCTTTTTSCCCEEEEEEE
T ss_pred             cccceeEEEEEeHHHcCCccceeCCCeEeCeeeEEECCCCCCCCCCCCcchHHHHHHHHHhcCCCCccCCCCccccceec
Confidence            678999999999999999889999999999999999998865321  12456655554321  12335679999999999


Q NP_000548.2     473 PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       473 ~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +++|||++++++++++.++||+|++|||+
T Consensus        88 ~l~il~~~~~~~~~~~~~~~m~v~~CgC~  116 (116)
T 2ARV_A           88 PMSMLYYDDGQNIIKKDIQNMIVEECGCS  116 (116)
T ss_dssp             EEEEEEEETTTEEEEEEEEEEEEEEEEEC
T ss_pred             cEEEEEEeCCCeEEEEEeCCeEEeeccCC
Confidence            99999999877788999999999999995


No 26
>2P6A_B Activin A, Follistatin 315; Follistatin, Activin,Inhibin, TGF-beta, SIGNALING PROTEIN; 3.4A {Homo sapiens} SCOP: g.17.1.2
Probab=99.79  E-value=1.3e-24  Score=184.92  Aligned_cols=105  Identities=38%  Similarity=0.831  Sum_probs=86.7  Template_Neff=8.700

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHL--EPTNHAVIQTLMNS--MDPESTPPTCCVPTRLS  472 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~--~~~~h~~i~~~~~~--~~~~~~~~pCC~P~~~~  472 (501)
                      ...||++.++|+|++|||++|||+|++|+++||.|.|+.+.....  +.++|+.++.++..  ..+.....|||+|++|+
T Consensus         8 ~~~C~~~~~~v~f~~lgw~~~Ii~P~~~~~~~C~G~C~~~~~~~~~~~~~~h~~~~~~~~~~~~~~~~~~~~CC~P~~~~   87 (116)
T 2P6A_B            8 VNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLR   87 (116)
T ss_pred             cccceeEEEEEeHHHcCCccceeCCCeEeCeeeEEECCCCCCCCCCCCcchHHHHHHHHHhcCCCCccCCCCccccceec
Confidence            678999999999999999889999999999999999998865321  12456655554321  12335679999999999


Q NP_000548.2     473 PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       473 ~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +++|||++++++++++.++||+|++|||+
T Consensus        88 ~l~il~~~~~~~~~~~~~~~m~v~~CgC~  116 (116)
T 2P6A_B           88 PMSMLYYDDGQNIIKKDIQNMIVEECGCS  116 (116)
T ss_pred             cEEEEEEeCCCeEEEEEeCCeEEeeccCC
Confidence            99999999877788999999999999995


No 27
>2TGI_A TRANSFORMING GROWTH FACTOR-BETA TWO (TGF-B2); GROWTH FACTOR; 1.8A {Homo sapiens} SCOP: g.17.1.2
Probab=99.79  E-value=1.5e-24  Score=183.69  Aligned_cols=101  Identities=35%  Similarity=0.828  Sum_probs=88.1  Template_Neff=8.200

Q NP_000548.2     396 LKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPI  474 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l  474 (501)
                      ....||+++++|+|+ +|||+ |||+|++|+++||.|.|..+...   .++|+.++.+++...+.....|||+|++|+++
T Consensus        11 ~~~~Cc~~~~~V~f~~~lgw~-~Ii~P~~~~~~~C~G~C~~~~~~---~~~h~~~~~~~~~~~~~~~~~~CC~P~~~~~l   86 (112)
T 2TGI_A           11 VQDNCCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGACPYLWSS---DTQHSRVLSLYNTINPEASASPCCVSQDLEPL   86 (112)
T ss_dssp             CCSBSEEECCEEECCCCCCCT-TEEECSEEECCEEECBCCTTSSB---CSHHHHHHHHHHHHCGGGCCCCCEEECSEEEE
T ss_pred             CCCCcEEEEEEEECchhhCCc-eeeCCCeEeceeecccCCCCCCC---cccHHHHHHHHHhcCcccCCCCceeceeecce
Confidence            478999999999999 99998 99999999999999999988653   34677777766544444678999999999999


Q NP_000548.2     475 SILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       475 ~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +|||++++ +++++.++||+|++|||+
T Consensus        87 ~il~~~~~-~~~~~~~~~m~v~~CgC~  112 (112)
T 2TGI_A           87 TILYYIGK-TPKIEQLSNMIVKSCKCS  112 (112)
T ss_dssp             EEEEEETT-EEEEEEEEEEEECCEEEC
T ss_pred             EEEEEeCC-ceEEEEeCCeEEEeCCCC
Confidence            99999986 578899999999999995


No 28
>3HH2_B Growth/differentiation factor 8, Follistatin; protein-protein complex, TB domain, cystine; HET: PO4, CIT; 2.15A {Mus musculus}
Probab=99.79  E-value=2.4e-24  Score=181.50  Aligned_cols=99  Identities=39%  Similarity=0.949  Sum_probs=82.7  Template_Neff=8.200

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|++|||+ |||+|++|+++||.|.|..+....   .+|+.   +++...+.....|||+|++|++++
T Consensus        11 ~~~~C~~~~~~V~f~~lgw~-~Ii~P~~~~~~~C~G~C~~~~~~~---~~~~~---l~~~~~~~~~~~~CC~P~~~~~l~   83 (109)
T 3HH2_B           11 TESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFLQK---YPHTH---LVHQANPRGSAGPCCTPTKMSPIN   83 (109)
T ss_dssp             CCCBSEEECCEEEHHHHTCT-TEEECSEEECCEEECBCCTTTTBC---CHHHH---HHHHHCCTTCCCCCEEEEEEEEEE
T ss_pred             CCCceeeeEEEEehHHhCCc-eEECCCeeeceEeceeCCCccccc---CCcce---ehhhcCCCCCCCCCccceeeCCeE
Confidence            46799999999999999998 999999999999999999987542   13332   222222235689999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|++++++++++.++||+|++|||+
T Consensus        84 il~~~~~~~~~~~~~~~m~v~~CgC~  109 (109)
T 3HH2_B           84 MLYFNGKEQIIYGKIPAMVVDRCGCS  109 (109)
T ss_dssp             EEEECTTCCEEEEEEEEEEEEEEEEC
T ss_pred             EEEEcCCCeEEEEEeCCeEEecccCC
Confidence            99999877788999999999999995


No 29
>5F3B_C RK35 Chimeric antibody heavy chain; myostatin, antibody, complex, Signaling Protein-Immune; HET: GOL; 1.76A {Mus musculus}
Probab=99.79  E-value=2.4e-24  Score=181.50  Aligned_cols=99  Identities=39%  Similarity=0.949  Sum_probs=82.7  Template_Neff=8.200

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|++|||+ |||+|++|+++||.|.|..+....   .+|+.   +++...+.....|||+|++|++++
T Consensus        11 ~~~~C~~~~~~V~f~~lgw~-~Ii~P~~~~~~~C~G~C~~~~~~~---~~~~~---l~~~~~~~~~~~~CC~P~~~~~l~   83 (109)
T 5F3B_C           11 TESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFLQK---YPHTH---LVHQANPRGSAGPCCTPTKMSPIN   83 (109)
T ss_pred             CCCceeeeEEEEehHHhCCc-eEECCCeeeceEeceeCCCccccc---CCcce---ehhhcCCCCCCCCCccceeeCCeE
Confidence            46799999999999999998 999999999999999999987542   13332   222222235689999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|++++++++++.++||+|++|||+
T Consensus        84 il~~~~~~~~~~~~~~~m~v~~CgC~  109 (109)
T 5F3B_C           84 MLYFNGKEQIIYGKIPAMVVDRCGCS  109 (109)
T ss_pred             EEEEcCCCeEEEEEeCCeEEecccCC
Confidence            99999877788999999999999995


No 30
>3KFD_D Transforming growth factor beta-1, TGF-beta; TGF-beta, TGF-b1, TGF-beta receptor type-1; 2.995A {Homo sapiens}
Probab=99.78  E-value=3.7e-24  Score=181.25  Aligned_cols=102  Identities=30%  Similarity=0.731  Sum_probs=87.9  Template_Neff=8.300

Q NP_000548.2     395 NLKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSP  473 (501)
Q Consensus       395 ~~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~  473 (501)
                      .....||+++++|+|+ +|||+ |||+|++|+++||.|.|..+...   .++|+.++.+++...+..+..|||+|++|++
T Consensus        10 ~~~~~C~~~~~~v~f~~~lg~~-~Ii~P~~~~~~~C~G~C~~~~~~---~~~~~~~~~~~~~~~~~~~~~~CC~P~~~~~   85 (112)
T 3KFD_D           10 STEKNCCVRQLYIDFRKDLGWK-WIHEPKGYHANFCLGPCPYIWSL---DTQYSKVLALYNQHNPGASAAPCCVPQALEP   85 (112)
T ss_pred             CCCCCcEEEEEEEECccccCCc-eeeCCCeEEeeeeceeCCCCCCC---cccHHHHHHHHHhhCCCCCCCCccccccccc
Confidence            3477899999999998 99998 99999999999999999988653   3467777766654444467899999999999


Q NP_000548.2     474 ISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       474 l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ++|+|++++ +++++.++||+|++|||+
T Consensus        86 l~ily~~~~-~~~~~~~~~m~v~~CgC~  112 (112)
T 3KFD_D           86 LPIVYYVGR-KPKVEQLSNMIVRSCKCS  112 (112)
T ss_pred             eeEEEEeCC-eEEEEEeCCeEEEecCCC
Confidence            999999987 577899999999999995


No 31
>5E4G_A Growth/differentiation factor 11; Bone morphogenetic protein 11, BMP-11; HET: PG4; 1.5A {Homo sapiens}
Probab=99.76  E-value=1.2e-23  Score=177.01  Aligned_cols=99  Identities=37%  Similarity=0.939  Sum_probs=83.0  Template_Neff=8.400

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPIS  475 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~  475 (501)
                      ....||+++++|+|+||||+ |||+|++|+++||.|+|..+....   .+|+.+   +....+..++.|||+|++|++++
T Consensus        11 ~~~~C~~~~~~V~f~~lgw~-~Ii~P~~~~~~~C~G~C~~~~~~~---~~~~~l---~~~~~~~~~~~~cC~P~~~~~l~   83 (109)
T 5E4G_A           11 SESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGQCEYMFMQK---YPHTHL---VQQANPRGSAGPCCTPTKMSPIN   83 (109)
T ss_dssp             CCCBSEEECCEEETTTTTCT-TEEECSEEECCEEECBCCTTTTCS---STHHHH---HHHHCCTTCCCCCEEEEEEEEEE
T ss_pred             CcCceEeEEEEEehHHcCCc-eEeCCCeeeceeecccCCcccccc---CCchHH---HHhcCCCCCCCCCccceeeccEE
Confidence            47799999999999999998 999999999999999999987532   133322   11122345789999999999999


Q NP_000548.2     476 ILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       476 ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+|++++++++++.++||+|++|||+
T Consensus        84 il~~~~~~~~~~~~~~d~~v~~C~C~  109 (109)
T 5E4G_A           84 MLYFNDKQQIIYGKIPGMVVDRCGCS  109 (109)
T ss_dssp             EEEECSSSCEEEEEEEEEEEEEEEEC
T ss_pred             EEEEcCCCeEEEEEeCCeEEeeccCC
Confidence            99999887888999999999999995


No 32
>5NMZ_B Neurturin; cystine knot, neurotrophic factor, GFL; HET: GOL; 1.6A {Homo sapiens}
Probab=99.71  E-value=2.2e-22  Score=166.98  Aligned_cols=93  Identities=22%  Similarity=0.465  Sum_probs=76.9  Template_Neff=8.300

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD---PESTPPTCCVPTRLS  472 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~---~~~~~~pCC~P~~~~  472 (501)
                      ...||+++++|+|+||||+ | |+|++|+++||.|.|..+..      +| +.++.+++...   +.....|||+|++|+
T Consensus         4 ~~~C~~~~~~v~f~dlgw~-~-i~P~~~~~~~C~G~C~~~~~------~~~~~~~~l~~~~~~~~~~~~~~~CC~P~~~~   75 (101)
T 5NMZ_B            4 ARPCGLRELEVRVSELGLG-Y-ASDETVLFRYCAGACEAAAR------VYDLGLRRLRQRRRLRRERVRAQPCCRPTAYE   75 (101)
T ss_dssp             CCBSEEEEEEEEGGGGTSS-C-CCCCEEEEEEEECBCGGGCC------HHHHHHHHHHTTTCSTTCCBCCSCCEEEEEEC
T ss_pred             CCCccceEEEEeHHHcCCe-e-ecCCeEECeeeceeCCchhh------chHHHHHHHHHhhhhhccccCCCCceeeeeec
Confidence            5689999999999999999 8 89999999999999999864      23 33444433322   246789999999999


Q NP_000548.2     473 -PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       473 -~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                       +++  |+|++  ++++.++||+|++|||+
T Consensus        76 ~~l~--y~d~~--~~~~~~~~m~v~~CgC~  101 (101)
T 5NMZ_B           76 DEVS--FLDAH--SRYHTVHELSARECACV  101 (101)
T ss_dssp             SEEE--EECTT--CCEEEEESCSEEEEEEC
T ss_pred             CceE--eecCC--cEEEEeCCeeeecccCC
Confidence             999  77764  78899999999999995


No 33
>5NMZ_C Neurturin; cystine knot, neurotrophic factor, GFL; HET: GOL; 1.6A {Homo sapiens}
Probab=99.71  E-value=2.2e-22  Score=166.98  Aligned_cols=93  Identities=22%  Similarity=0.465  Sum_probs=76.9  Template_Neff=8.300

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD---PESTPPTCCVPTRLS  472 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~---~~~~~~pCC~P~~~~  472 (501)
                      ...||+++++|+|+||||+ | |+|++|+++||.|.|..+..      +| +.++.+++...   +.....|||+|++|+
T Consensus         4 ~~~C~~~~~~v~f~dlgw~-~-i~P~~~~~~~C~G~C~~~~~------~~~~~~~~l~~~~~~~~~~~~~~~CC~P~~~~   75 (101)
T 5NMZ_C            4 ARPCGLRELEVRVSELGLG-Y-ASDETVLFRYCAGACEAAAR------VYDLGLRRLRQRRRLRRERVRAQPCCRPTAYE   75 (101)
T ss_dssp             CCBSEEEEEEEEGGGGTSS-S-CCCCEEEEEEEECBCCTTSC------HHHHHHHHHHHTTCSTTCCCCCSCCEEEEEEC
T ss_pred             CCCccceEEEEeHHHcCCe-e-ecCCeEECeeeceeCCchhh------chHHHHHHHHHhhhhhccccCCCCceeeeeec
Confidence            5689999999999999999 8 89999999999999999864      23 33444433322   246789999999999


Q NP_000548.2     473 -PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       473 -~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                       +++  |+|++  ++++.++||+|++|||+
T Consensus        76 ~~l~--y~d~~--~~~~~~~~m~v~~CgC~  101 (101)
T 5NMZ_C           76 DEVS--FLDAH--SRYHTVHELSARECACV  101 (101)
T ss_dssp             SCEE--EECTT--SCEEEESSCSEEEEEEC
T ss_pred             CceE--eecCC--cEEEEeCCeeeecccCC
Confidence             999  77764  78899999999999995


No 34
>2GH0_C artemin, GDNF family receptor alpha-3; cystine-knot, helix bundle, HORMONE-GROWTH FACTOR; HET: BMA, NAG, MAN; 1.92A {Homo sapiens}
Probab=99.71  E-value=2.9e-22  Score=166.00  Aligned_cols=95  Identities=19%  Similarity=0.418  Sum_probs=77.9  Template_Neff=8.600

Q NP_000548.2     398 ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMD----PESTPPTCCVPTRLSP  473 (501)
Q Consensus       398 ~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~----~~~~~~pCC~P~~~~~  473 (501)
                      ..||+++++|+|+||||++|||  ++|+++||.|.|+.+....  .+.|+.++.++ ...    ....+.|||+|++|++
T Consensus         2 ~~C~~~~~~V~f~dlgw~~~I~--~~~~~~~C~G~C~~~~~~~--~~~~~~l~~~~-~~~~~~~~~~~~~~CC~P~~~~~   76 (101)
T 2GH0_C            2 PGCRLRSQLVPVRALGLGHRSD--ELVRFRFCSGSCRRARSPH--DLSLASLLGAG-ALRPPPGSRPVSQPCCRPTRYEA   76 (101)
T ss_pred             CCCcceEEEEeHHHcCCCcccC--cEEecceeeeeCCCCCCCc--cchHHHHHHcc-cCCCCCCCCCCCCCceeeeeecc
Confidence            4799999999999999988988  9999999999999987642  23455554443 111    1357899999999999


Q NP_000548.2     474 ISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       474 l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ++|||+++    +++.++||+|++|||+
T Consensus        77 l~il~~~~----~~~~~~~m~v~~CgC~  100 (101)
T 2GH0_C           77 VSFMDVNS----TWRTVDRLSATACGCL  100 (101)
T ss_pred             eEEEEeCC----eeEEEcceEeeccccc
Confidence            99999875    5789999999999995


No 35
>5MR4_B Neurturin, GDNF family receptor alpha-2; Complex, Signalling, Receptor, signaling protein; 2.4A {Homo sapiens}
Probab=99.70  E-value=4.4e-22  Score=165.39  Aligned_cols=94  Identities=21%  Similarity=0.445  Sum_probs=76.5  Template_Neff=8.200

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD---PESTPPTCCVPTRL  471 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~---~~~~~~pCC~P~~~  471 (501)
                      ....||+++++|+|+||||+ | |+|++|+++||.|.|+.+..      +| +.++.++....   +.....|||+|++|
T Consensus         4 ~~~~C~~~~~~v~f~dlgw~-~-i~P~~~~~~~C~G~C~~~~~------~~~~~~~~~~~~~~~~~~~~~~~~CC~P~~~   75 (102)
T 5MR4_B            4 GARPCGLRELEVRVSELGLG-Y-ASDETVLFRYCAGACEAAAR------VYDLGLRRLRQRRRLRRERVRAQPCCRPTAY   75 (102)
T ss_dssp             -CCBSEEEEEEEEGGGGSSS-C-CCCCEEEEEEEESBCCSCCC------HHHHHHHHHHHTTCSTTCCCCCSCCEEEEEE
T ss_pred             CCCCceeeEEEEEHHHcCCc-e-eCCCeEECeeeceeCCchhc------chHHHHHHHHHhhhhhccccCCCCceeeeee
Confidence            35789999999999999998 7 89999999999999999864      23 33333333222   24678999999999


Q NP_000548.2     472 S-PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       472 ~-~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      + +++  |+|++  ++++.++||+|++|||+
T Consensus        76 ~~~l~--y~d~~--~~~~~~~~m~v~~CgC~  102 (102)
T 5MR4_B           76 EDEVS--FLDAH--SRYHTVHELSARECACV  102 (102)
T ss_dssp             CCEEE--EECTT--SCEEEEESCSEEEEEEC
T ss_pred             cCceE--eecCC--cEEEEECCeeeccccCC
Confidence            9 999  77764  78999999999999995


No 36
>2V5E_B GDNF FAMILY RECEPTOR ALPHA-1, GLIAL; RECEPTOR-GLYCOPROTEIN COMPLEX, CELL MEMBRANE, GROWTH; HET: NAG, EDO, SCR; 2.35A {RATTUS NORVEGICUS}
Probab=99.69  E-value=7.4e-22  Score=163.65  Aligned_cols=93  Identities=24%  Similarity=0.547  Sum_probs=77.2  Template_Neff=8.400

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD--PESTPPTCCVPTRLS-  472 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~--~~~~~~pCC~P~~~~-  472 (501)
                      ...||+++++|+|+||||+ | |+|++|+++||.|.|+.+..      +| +.++.+++...  +..+..|||+|++|+ 
T Consensus         5 ~~~C~~~~~~V~f~~lgw~-~-i~P~~~~~~~C~G~C~~~~~------~h~~~~~~l~~~~~~~~~~~~~~CC~P~~~~~   76 (101)
T 2V5E_B            5 NRGCVLTAIHLNVTDLGLG-Y-ETKEELIFRYCSGSCDAAET------TYDKILKNLSRNRRLVSDKVGQACCRPIAFDD   76 (101)
T ss_dssp             TTTCEEEEEEEEGGGGCSS-C-CCSCEEEEEEEESCCCSCCS------HHHHHHHHHHHTTSSSSSSTTCCCEEEEEECC
T ss_pred             CCcceeeEEEEEHHHcCCc-c-cCCCeEECceecEeCCCCCC------cHHHHHHHHHhccCCCcccCCCCeEEeeEecC
Confidence            5689999999999999998 7 89999999999999999842      45 44554443321  345789999999999 


Q NP_000548.2     473 PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       473 ~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +++  |+|++  ++++.++||+|++|||+
T Consensus        77 ~l~--y~d~~--~~~~~~~~m~v~~CgC~  101 (101)
T 2V5E_B           77 DLS--FLDDN--LVYHILRKHSAKRCGCI  101 (101)
T ss_dssp             CEE--EECTT--SCEEEECSCSEEEEEEC
T ss_pred             ceE--EecCC--EEEEEecCcEecccccC
Confidence            999  77775  57899999999999995


No 37
>2ASK_B artemin; Glial cell derived family ligand; HET: SO4; 1.55A {Homo sapiens}
Probab=99.69  E-value=9.1e-22  Score=166.60  Aligned_cols=94  Identities=20%  Similarity=0.467  Sum_probs=77.2  Template_Neff=8.000

Q NP_000548.2     396 LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD------PESTPPTCCVP  468 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~------~~~~~~pCC~P  468 (501)
                      ....||+++++|+|+||||+ | |+|++|+++||.|.|..+.      ++| +.++.+++...      ......|||+|
T Consensus        12 ~~~~Cc~~~~~V~F~dlgw~-~-i~P~~~~~~~C~G~C~~~~------~~h~~~~~~l~~~~~~~~~~~~~~~~~~CC~P   83 (113)
T 2ASK_B           12 GARGCRLRSQLVPVRALGLG-H-RSDELVRFRFCSGSCRRAR------SPHDLSLASLLGAGALRPPPGSRPVSQPCCRP   83 (113)
T ss_dssp             -CCBSEEEEEEEEGGGGSSS-C-CBSSEEEEEEEECBCGGGC------CHHHHHHHHHHHTTCSCCCSSSCCCCSCEEEE
T ss_pred             CCCCceeEEEEEEHHHcCCC-c-cCCCeEECceEeeeCCCCC------CCcHHHHHHHHHccCCCCCCCCCCCCCCceee
Confidence            46799999999999999998 6 7999999999999999983      245 45555554332      23578999999


Q NP_000548.2     469 TRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       469 ~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ++|++++  |+|++  +++++++||+|++|||.
T Consensus        84 ~~~~~l~--y~d~~--~~~~~l~~miv~~CgC~  112 (113)
T 2ASK_B           84 TRYEAVS--FMDVN--STWRTVDRLSATACGCL  112 (113)
T ss_dssp             EEEEEEE--EEBTT--SCEEEEEEEEEEEEEEE
T ss_pred             eEeceee--eecCC--cEEEEECCeEEeccccc
Confidence            9999877  77775  67899999999999995


No 38
>3FUB_D GDNF family receptor alpha-1, Glial; GFRALPHA1, ALL ALPHA GDNF, CYSTINE; HET: NAG, EDO; 2.35A {Rattus norvegicus}
Probab=99.69  E-value=9.6e-22  Score=171.18  Aligned_cols=96  Identities=24%  Similarity=0.517  Sum_probs=80.0  Template_Neff=6.800

Q NP_000548.2     394 KNLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSM--DPESTPPTCCVPTR  470 (501)
Q Consensus       394 ~~~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~--~~~~~~~pCC~P~~  470 (501)
                      ......||++.++|+|+||||+ | |+|++|+++||.|.|.++.      ++| ++++.+++..  .+..+..|||+|++
T Consensus        35 ~~~~~~Ccr~~l~V~F~dlGw~-~-iaP~~f~~~~C~G~C~~~~------t~h~~~l~~l~~~~~~~~~~~~~pCCvP~~  106 (134)
T 3FUB_D           35 RGKNRGCVLTAIHLNVTDLGLG-Y-ETKEELIFRYCSGSCDAAE------TTYDKILKNLSRNRRLVSDKVGQACCRPIA  106 (134)
T ss_pred             CCCCCcceEEEEEEeHHHcCCC-c-cCCCeEEeEEeeCCCCCCc------chHHHHHHHHHHcCCCCCCCCCCCeeeeeE
Confidence            3457899999999999999998 6 5999999999999999982      356 5666665543  12357899999999


Q NP_000548.2     471 LS-PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       471 ~~-~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      |+ +++  |++++ + ++++++||+|++|||.
T Consensus       107 ~~~~l~--y~d~~-~-~~~~l~~mvv~~CgC~  134 (134)
T 3FUB_D          107 FDDDLS--FLDDN-L-VYHILRKHSAKRCGCI  134 (134)
T ss_pred             eCCcee--EECCC-c-eEEEEcCeEEecccCC
Confidence            99 988  77776 4 7899999999999995


No 39
>1AGQ_C GLIAL CELL-DERIVED NEUROTROPHIC FACTOR; GROWTH FACTOR, NEUROTROPHIC FACTOR, CYSTINE; 1.9A {Rattus norvegicus} SCOP: g.17.1.2
Probab=99.67  E-value=2.2e-21  Score=169.01  Aligned_cols=95  Identities=26%  Similarity=0.544  Sum_probs=76.0  Template_Neff=6.700

Q NP_000548.2     395 NLKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD--PESTPPTCCVPTRL  471 (501)
Q Consensus       395 ~~~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~--~~~~~~pCC~P~~~  471 (501)
                      .....||++.++|+|+||||+ | |+|.+|+++||.|.|.++.      ++| ++++.+++...  +..+..|||+|++|
T Consensus        37 ~~~~~Cc~~~l~V~F~dlGW~-i-iaP~~~~~~~C~G~C~~~~------t~h~~~l~~l~~~~~~~~~~~~~pCCvP~~~  108 (135)
T 1AGQ_C           37 GKNRGCVLTAIHLNVTDLGLG-Y-ETKEELIFRYCSGSCEAAE------TMYDKILKNLSRSRRLTSDKVGQACCRPVAF  108 (135)
T ss_dssp             ----CCEEEEEEEEGGGGCSC-C-CCCCEEEEEEEESCCCCCC------SHHHHHHHHHHHTTCC----CCCCCEEEEEE
T ss_pred             CCCCCceEEEEEEEHHHcCCC-c-cCCCeEEeEEecCCCCCCc------chHHHHHHHHHhhcCCCCcccCCCeeeeeee
Confidence            457899999999999999998 5 8999999999999999972      367 66666655432  33578999999999


Q NP_000548.2     472 S-PISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       472 ~-~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      + +++  |++++  +++++++||+|++|||.
T Consensus       109 ~~~l~--y~d~~--~~~~~l~dmiv~~CgC~  135 (135)
T 1AGQ_C          109 DDDLS--FLDDS--LVYHILRKHSAKRCGCI  135 (135)
T ss_dssp             CCCEE--EECSS--SCEEEECSCSEEEEEEC
T ss_pred             cCCee--eecCC--eEEEEEcCeEEecccCC
Confidence            9 999  77765  47899999999999995


No 40
>5TX2_A Transforming growth factor beta-2; Growth factor, CYTOKINE; 1.82A {Mus musculus}
Probab=99.66  E-value=2.9e-21  Score=157.69  Aligned_cols=81  Identities=33%  Similarity=0.827  Sum_probs=74.0  Template_Neff=7.400

Q NP_000548.2     396 LKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPI  474 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l  474 (501)
                      ....||+++++|+|+ ||||+ |||+|++|+++||.|.|..+.                       .+.+||+|++|+++
T Consensus        12 ~~~~C~~~~~~v~f~~dlgw~-~Ii~P~~~~~~~C~G~C~~~~-----------------------~~~~CC~P~~~~~l   67 (93)
T 5TX2_A           12 VQDNCCLRPLYIDFKRDLGWK-WIHEPKGYNANFCAGACPYRA-----------------------SKSPSCVSQDLEPL   67 (93)
T ss_dssp             CCSBSEEECCEEEHHHHHCCC-SEEECSEEECCEEECBCCCCS-----------------------SSCCCEEECCEEEE
T ss_pred             CCCCcEEEEEEEECchhcCCC-cEeCCCeEEcEEecccCCCCC-----------------------CCCCCceeceecce
Confidence            478999999999999 99998 999999999999999998751                       25799999999999


Q NP_000548.2     475 SILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       475 ~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +|||++++ +++++.++||+|++|||+
T Consensus        68 ~il~~~~~-~~~~~~l~~~~v~~CgC~   93 (93)
T 5TX2_A           68 TILYYIGN-TPKIEQLSNMIVKSCKCS   93 (93)
T ss_dssp             EEEEEETT-EEEEEEEEEEEECEEEEC
T ss_pred             EEEEEeCC-eEEEEEEcCcEEecCccC
Confidence            99999986 578999999999999995


No 41
>5TX4_B TGF-beta receptor type-2 (E.C.2.7.11.30), Transforming; TGF-beta, TGF-beta type II receptor; 1.876A {Homo sapiens}
Probab=99.66  E-value=3e-21  Score=157.29  Aligned_cols=81  Identities=31%  Similarity=0.818  Sum_probs=74.3  Template_Neff=7.500

Q NP_000548.2     396 LKARCSRKALHVNFK-DMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPI  474 (501)
Q Consensus       396 ~~~~Cc~~~l~V~F~-dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l  474 (501)
                      ....||+++++|+|+ +|||+ |||+|++|+++||.|.|..+.                       .+.|||+|++|+++
T Consensus        11 ~~~~C~~~~~~v~f~~~lgw~-~Ii~P~~~~~~~C~G~C~~~~-----------------------~~~~CC~P~~~~~~   66 (92)
T 5TX4_B           11 VQDNCCLRPLYIDFRKDLGWK-WIHEPKGYNANFCAGACPYRA-----------------------SKSPSCVSQDLEPL   66 (92)
T ss_pred             CCCCcEEEEEEEECchhcCCC-ceeCCCeEEcEEeeccCCCCC-----------------------CCCCceeccccCce
Confidence            467999999999998 99998 999999999999999998752                       25799999999999


Q NP_000548.2     475 SILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       475 ~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +|||++++ +++++.++||+|++|+|+
T Consensus        67 ~il~~~~~-~i~~~~~~~~~v~~C~C~   92 (92)
T 5TX4_B           67 TIVYYVGR-KPKVEQLSNMIVKSCKCS   92 (92)
T ss_pred             eEEEEeCC-eeEEEEEcCeEEecCCCC
Confidence            99999987 678999999999999995


No 42
>2GYZ_A neurotrophic factor artemin isoform 3; neurotrophic factor, cystine-knot, HORMONE-GROWTH FACTOR; 1.76A {Homo sapiens}
Probab=99.57  E-value=1.4e-19  Score=150.88  Aligned_cols=89  Identities=18%  Similarity=0.342  Sum_probs=71.6  Template_Neff=7.300

Q NP_000548.2     399 RCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD------PESTPPTCCVPTRL  471 (501)
Q Consensus       399 ~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~------~~~~~~pCC~P~~~  471 (501)
                      .||+++++|+|+||||+  ||+|++|+++||.|+|..+..      ++ +.++.++....      +.....|||+|++|
T Consensus         1 ~Cc~~~l~V~F~dlGw~--IiaP~~~~a~yC~G~C~~~~~------~~~~~~~~l~~~~~~~~~~~~~~~~~pCC~P~~~   72 (105)
T 2GYZ_A            1 GCRLRSQLVPVRALGLG--HRSDELVRFRFCSGSCRRARS------PHDLSLASLLGAGALRPPPGSRPVSQPCCRPTRY   72 (105)
T ss_dssp             CCEEEEEEEEGGGGSSS--CCCSSEEEEEEEESCCGGGCC------HHHHHHHHHHHTTCSCCCSSSCCCSSCCCEEEEE
T ss_pred             CCeeEEEEEeHHHcCCc--cccCCceeceEEeccCCCCCC------chHHHHHHHHHhcCCCCCCCCCCCCCCeeeeeee
Confidence            49999999999999998  899999999999999999853      22 23323332221      24578999999999


Q NP_000548.2     472 SPISILFIDSA-NNVVYKQYEDMVVES  497 (501)
Q Consensus       472 ~~l~ily~d~~-~~~~~~~~~~mvv~~  497 (501)
                      ++++  |+|++ +.+++++++||+|..
T Consensus        73 ~~l~--y~d~~~~~i~~~~lp~m~~~~   97 (105)
T 2GYZ_A           73 EAVS--FMDVNSTWRTVDRLSATACGC   97 (105)
T ss_dssp             EEEE--EECTTSCEEEEEEEEEEEEEC
T ss_pred             ceee--EEeCCCCeEEEEEeccceeec
Confidence            9999  88876 578899999999875


No 43
>6Q2S_B Ubiquitin-like protein SMT3,Artemin, GDNF family; RET, receptor tyrosine kinase, cryo-EM; HET: NAG; 3.8A {Saccharomyces cerevisiae}
Probab=99.47  E-value=2.9e-18  Score=163.18  Aligned_cols=93  Identities=20%  Similarity=0.483  Sum_probs=77.2  Template_Neff=8.400

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNH-AVIQTLMNSMD------PESTPPTCCVPT  469 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h-~~i~~~~~~~~------~~~~~~pCC~P~  469 (501)
                      ...||++.++|+|++|||+  ||+|.+|+++||.|.|..+.      ++| +.++.+++...      ......|||+|+
T Consensus       135 ~~~C~~~~~~V~f~~lgw~--ii~P~~~~~~~C~G~C~~~~------~~~~~~~~~l~~~~~~~~~~~~~~~~~~CC~P~  206 (235)
T 6Q2S_B          135 ARGCRLRSQLVPVRALGLG--HRSDELVRFRFCSGSCRRAR------SPHDLSLASLLGAGALRPPPGSRPVSQPCCRPT  206 (235)
T ss_pred             CceeeeecCccchHHcCCe--eecCCeEECccccCCCCCCC------CCHHHHHHHHHHcCCCCCCCCCCCCCCCccCce
Confidence            5789999999999999998  58999999999999999983      255 45555554332      135789999999


Q NP_000548.2     470 RLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       470 ~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      +|++++  |++++  +++++++||+|++|||+
T Consensus       207 ~~~~l~--y~~~~--~~~~~~~~m~v~~CgC~  234 (235)
T 6Q2S_B          207 RYEAVS--FMDVN--STWRTVDRLSATACGCL  234 (235)
T ss_pred             ecCeee--eecCC--eEEEEeCCcEEeccccc
Confidence            999988  77764  67899999999999995


No 44
>6GFF_E Transforming growth factor beta-1, Leucine-rich; GARP, TGF-B1, Activation, Treg, IMMUNE; HET: BMA, MAN, NAG; 3.1A {Mus musculus}
Probab=98.95  E-value=1.1e-13  Score=131.10  Aligned_cols=158  Identities=22%  Similarity=0.234  Sum_probs=101.3  Template_Neff=9.700

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGN------SSVKLEAGLANTITSFIDKGQDDRG-P  215 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~~------~~~~~~~~~~n~Vrsf~~~~~~~~~-~  215 (501)
                      .+||++|||+++|+++..    .+.+++++|++||+.+.........      ..+.+....+++|++|......... .
T Consensus        22 ~~IL~~Lgl~~~P~~~~~----~~~~~p~~m~~lY~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~s~~~~~~~~~~~~   97 (249)
T 6GFF_E           22 GQILSKLRLASPPSQGEV----PPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQ   97 (249)
T ss_pred             HHHHHHcCCCCCCCCCCC----CCCCccHHHHHHHHhhhccccCCCCCcccCCcccchhcccceeeeecCCCCCCCcccC
Confidence            689999999999998651    1245689999999987665321100      0111223456788888654332100 1


Q NP_000548.2     216 VVRKQRYVFDISALE----K-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQPAALLDVRSVPGLDGSG  290 (501)
Q Consensus       216 ~~~~~~l~FnlSsi~----~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~~~~~ll~s~~v~~~~~~g  290 (501)
                      ......+.|++++++    . +.|.+|+||||+.....           ...|.||...... ...++..+.+.....++
T Consensus        98 ~~~~~~l~F~ls~~~~~~~~~~~v~~AeL~l~~~~~~~-----------~~~v~iy~~~~~~-~~~~l~~~~v~~~~~~~  165 (249)
T 6GFF_E           98 STHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKV-----------EQHVELYQKYSNN-SWRYLSNRLLAPSDSPE  165 (249)
T ss_pred             CCCcEEEEEecccCCCCCCCccceEEEEEEEEeCCCCC-----------cEEEEEEEecCCC-ceeEEEEEEeecCCCCc
Confidence            234677999999742    2 47999999999987642           3566777643210 11123333221234579


Q NP_000548.2     291 WEVFDIWKLFRNFKNSA--QLCLELEAW  316 (501)
Q Consensus       291 Wv~fDVT~aV~~Wl~~~--nlgL~V~~~  316 (501)
                      |+.||||.+|+.|+.++  +++|.|.+.
T Consensus       166 W~~~dvt~~v~~W~~~~~~n~gl~v~v~  193 (249)
T 6GFF_E          166 WLSFDVTGVVRQWLSRGGEIEGFRLSAH  193 (249)
T ss_pred             eEEEEcHHHHHHHHhCCcccceEEEEEE
Confidence            99999999999999986  788886554


No 45
>6GFF_G Transforming growth factor beta-1, Leucine-rich; GARP, TGF-B1, Activation, Treg, IMMUNE; HET: MAN, NAG, BMA; 3.1A {Mus musculus}
Probab=98.95  E-value=1.1e-13  Score=131.18  Aligned_cols=158  Identities=22%  Similarity=0.234  Sum_probs=101.5  Template_Neff=9.600

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGN------SSVKLEAGLANTITSFIDKGQDDRG-P  215 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~~------~~~~~~~~~~n~Vrsf~~~~~~~~~-~  215 (501)
                      .+||++|||+++|++...    .+.+++++|++||+.+.........      ..+.+....+++|++|......... .
T Consensus        22 ~~IL~~LgL~~~P~~~~~----~~~~~p~~m~~lY~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~s~~~~~~~~~~~~   97 (249)
T 6GFF_G           22 GQILSKLRLASPPSQGEV----PPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVETHNEIYDKFKQ   97 (249)
T ss_dssp             HHHHHHTTCSSCCCSTTC----CSSSCCHHHHHHHHHHHSCCCCC-------CGGGTSCEEEEEEECCCCCCCCHHHSCC
T ss_pred             HHHHHHcCCCCCCCCCCC----CCCCChHHHHHHHHHHHhhccCCCCCCCCCChhhhhhheeEeeEEeeccccccccccc
Confidence            689999999999998651    2235689999999987655321100      0111223456788887654332100 1


Q NP_000548.2     216 VVRKQRYVFDISALE----K-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQPAALLDVRSVPGLDGSG  290 (501)
Q Consensus       216 ~~~~~~l~FnlSsi~----~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~~~~~ll~s~~v~~~~~~g  290 (501)
                      ......+.|++++++    . +.|.+|+||||+.....           ...|.||...... ...++..+.+.....++
T Consensus        98 ~~~~~~l~F~ls~~~~~~~~~~~v~~AeL~l~~~~~~~-----------~~~v~iy~~~~~~-~~~~l~~~~v~~~~~~~  165 (249)
T 6GFF_G           98 STHSIYMFFNTSELREAVPEPVLLSRAELRLLRLKLKV-----------EQHVELYQKYSNN-SWRYLSNRLLAPSDSPE  165 (249)
T ss_dssp             CTTEEEEEEEHHHHHHHSSSGGGEEEEEEEEEECCBSS-----------CEEEEEEECCSSS-CCEEEEEEEECCBSSCE
T ss_pred             CCCcEEEEeehHHhhccCCCcceEEEEEEEEEEcCCCc-----------eEEEEEEEecCCC-ceeEeEEEEeCCCCCCC
Confidence            234677999999752    2 47999999999987642           3567777643210 11123333221234579


Q NP_000548.2     291 WEVFDIWKLFRNFKNSA--QLCLELEAW  316 (501)
Q Consensus       291 Wv~fDVT~aV~~Wl~~~--nlgL~V~~~  316 (501)
                      |+.||||.+|+.|+.++  +++|.|.+.
T Consensus       166 W~~~dVt~~v~~W~~~~~~n~~l~v~v~  193 (249)
T 6GFF_G          166 WLSFDVTGVVRQWLSRGGEIEGFRLSAH  193 (249)
T ss_dssp             EEEEECHHHHHHHHHSCCSEEEEEEEEC
T ss_pred             eEEEEhHHHHHHHHHcCCCccCEEEEEE
Confidence            99999999999999987  788886554


No 46
>5HLZ_E Inhibin beta A chain; Growth factor, Precursor, Signalling, Signaling; 2.851A {Homo sapiens}
Probab=98.74  E-value=1.8e-12  Score=124.55  Aligned_cols=155  Identities=15%  Similarity=0.223  Sum_probs=99.6  Template_Neff=9.000

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGG------N----SSVKLEAGLANTITSFIDKGQDD  212 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~------~----~~~~~~~~~~n~Vrsf~~~~~~~  212 (501)
                      .+||++|||+.+|+++..    .+  .+++|++||+.+........      +    ..++.....+++|++|.+.+.  
T Consensus        41 ~~IL~~LGl~~~P~~~~~----~~--~p~~M~~LY~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~I~sf~~~~~--  112 (270)
T 5HLZ_E           41 KHILNMLHLKKRPDVTQP----VP--KAALLNAIRKLHVGKVGENGYVEIEDDIGRRAEMNELMEQTSEIITFAESGT--  112 (270)
T ss_pred             HHHHHHcCCCCCCCCCCC----CC--hHHHHHHHHHhhcCcccCCCceeccccccchhhhhhhhcceEEEEEEecCCC--
Confidence            689999999999998651    11  38999999998765442100      0    001123345678888876532  


Q NP_000548.2     213 RGPVVRKQRYVFDISA-LEK-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGR------------------  272 (501)
Q Consensus       213 ~~~~~~~~~l~FnlSs-i~~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~------------------  272 (501)
                           ....+.|+++. .+. +.|.+|+||||+.......      ......+.||......                  
T Consensus       113 -----~~~~l~F~~s~~~~~~~~v~~AeL~l~~~~~~~~~------~~~~~~i~vy~~~~~~~~~~~~~~~~~~~g~~~~  181 (270)
T 5HLZ_E          113 -----ARKTLHFEISKEGSDLSVVERAEVWLFLKVPKANR------TRTKVTIRLFQQQKHPQGSLDTGEEAEEVGLKGE  181 (270)
T ss_pred             -----ccEEEEEEecCCCCCceeEEEEEEEEEEeCCCcCC------CcceEEEEEEEEeeCCCCCCCCCchhhhhcCCcc
Confidence                 34578999987 433 4699999999998764310      1124566777543210                  


Q NP_000548.2     273 QPAALLDVRSVPGLDGSGWEVFDIWKLFRNFKNSA--QLCLELEAWE  317 (501)
Q Consensus       273 ~~~~ll~s~~v~~~~~~gWv~fDVT~aV~~Wl~~~--nlgL~V~~~~  317 (501)
                      ....++.++.+ .....+|++|||+.+|+.|+..+  +++|.|.+..
T Consensus       182 ~~~~ll~s~~v-~~~~~gW~~fdVt~~v~~W~~~~~~n~gl~v~~~~  227 (270)
T 5HLZ_E          182 RSELLLSEKVV-DARKSTWHVFPVSSSIQRLLDQGKSSLDVRIACEQ  227 (270)
T ss_pred             ceEEEEEEEEe-ecCCCceEEEEChHHHHHHHHcCCCCeeEEEEEEe
Confidence            01112333333 23457999999999999999986  7898887754


No 47
>4YCG_B pro-BMP9 prodomain, human BMP9 growth; pro-BMP complex, morphogen, transforming growth; HET: NAG, ZN; 3.3A {Mus musculus}
Probab=98.69  E-value=3.5e-12  Score=124.35  Aligned_cols=152  Identities=18%  Similarity=0.323  Sum_probs=81.5  Template_Neff=8.500

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGNSSVKLEAGLANTITSFIDKGQDDRG----PVVR  218 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~~~~~~~~~~~~n~Vrsf~~~~~~~~~----~~~~  218 (501)
                      .+||++|||.++|++...     ...+++||++||+.+......         ...+++|++|.+.......    ....
T Consensus        41 ~~IL~~LgL~~~P~~~~~-----~~~~p~yMl~LY~~~~~~~~~---------~~~~ntvRsf~~~~~~~~~~~~~~~~~  106 (296)
T 4YCG_B           41 VDFLRSLNLSGIPSQDKT-----RAEPPQYMIDLYNRYTTDKSS---------TPASNIVRSFSVEDAISTAATEDFPFQ  106 (296)
T ss_dssp             -------------------------CCCHHHHHHHHHHHHCTTS---------CCSCSEEEEEECCEEEEECCCSSSCSE
T ss_pred             HHHHHHCCCCCCCCCCCC-----CCCCCHHHHHHHHHhhcCCCC---------CCCccceeeeehhhhcccccCCCCCCC
Confidence            589999999999997641     124589999999987655321         1245677777654332110    0124


Q NP_000548.2     219 KQRYVFDISALEK-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQ-------PAALLDVRSVPGLDGSG  290 (501)
Q Consensus       219 ~~~l~FnlSsi~~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~~-------~~~ll~s~~v~~~~~~g  290 (501)
                      ...+.|+++ ++. +.|..|+||||+........    .......|.||.......       ...++...   .....+
T Consensus       107 ~~~L~F~lS-~p~~e~v~~AeLrl~~~~~~~~~~----~~~~~~~V~Vy~v~~~~~~~~~~~~~~~lL~~~---~~~~~g  178 (296)
T 4YCG_B          107 KHILIFNIS-IPRHEQITRAELRLYVSCQNDVDS----THGLEGSMVVYDVLEDSETWDQATGTKTFLVSQ---DIRDEG  178 (296)
T ss_dssp             EEEEECCCC-CCTTEEEEEEEEEEEEEECSCTTG----GGCCCEEEEEEEEEECCSSCSSSSSEEEEEEEE---EECSSE
T ss_pred             cEEEEEEEe-cCchhceEEEEEEEEeecCCCccC----CCCcEEEEEEEEeccccccccccCCcEEEEEEE---EcCCCe
Confidence            567899998 653 68999999999887643110    011245677776432100       01112222   234579


Q NP_000548.2     291 WEVFDIWKLFRNFKNSA----QLCLELEAW  316 (501)
Q Consensus       291 Wv~fDVT~aV~~Wl~~~----nlgL~V~~~  316 (501)
                      |+.||||.+|+.|+.++    +++|+|.+.
T Consensus       179 W~~fDVT~~V~~W~~~~~~~~~~gL~v~~~  208 (296)
T 4YCG_B          179 WETLEVSSAVKRWVRADSTTNKNKLEVTVQ  208 (296)
T ss_dssp             EEEEECHHHHHHHHSCCSSSCCSEEEEEEE
T ss_pred             eEEEEhHHHHHHHHHCCCCCCCceEEEEEE
Confidence            99999999999999985    478887664


No 48
>4YCI_B mouse pro-BMP9 prodomain, pro-BMP9 growth; pro-BMP complex, morphogen, transforming growth; HET: ZN, NAG; 3.25A {Mus musculus}
Probab=98.69  E-value=3.5e-12  Score=124.35  Aligned_cols=152  Identities=18%  Similarity=0.323  Sum_probs=81.5  Template_Neff=8.500

Q NP_000548.2     143 SFLLKKAREPGPPREPKEPFRPPPITPHEYMLSLYRTLSDADRKGGNSSVKLEAGLANTITSFIDKGQDDRG----PVVR  218 (501)
Q Consensus       143 ~qIL~kLGL~~~P~~~~~~~~~~~~~~p~~MldLY~~~~~~~~~~~~~~~~~~~~~~n~Vrsf~~~~~~~~~----~~~~  218 (501)
                      .+||++|||.++|++...     ...+++||++||+.+......         ...+++|++|.+.......    ....
T Consensus        41 ~~IL~~LgL~~~P~~~~~-----~~~~p~yMl~LY~~~~~~~~~---------~~~~ntvRsf~~~~~~~~~~~~~~~~~  106 (296)
T 4YCI_B           41 VDFLRSLNLSGIPSQDKT-----RAEPPQYMIDLYNRYTTDKSS---------TPASNIVRSFSVEDAISTAATEDFPFQ  106 (296)
T ss_dssp             -------------------------CCCHHHHHHHHHHHHCTTS---------CCSCSEEEEEECCEEEEECCCSSSCSE
T ss_pred             HHHHHHCCCCCCCCCCCC-----CCCCCHHHHHHHHHhhcCCCC---------CCCccceeeeehhhhcccccCCCCCCC
Confidence            589999999999997641     124589999999987655321         1245677777654332110    0124


Q NP_000548.2     219 KQRYVFDISALEK-DGLLGAELRILRKKPSDTAKPAAPGGGRAAQLKLSSCPSGRQ-------PAALLDVRSVPGLDGSG  290 (501)
Q Consensus       219 ~~~l~FnlSsi~~-e~V~~AeLrLy~~~~~~~~~~~~~~~~~~~~v~Vy~~~~~~~-------~~~ll~s~~v~~~~~~g  290 (501)
                      ...+.|+++ ++. +.|..|+||||+........    .......|.||.......       ...++...   .....+
T Consensus       107 ~~~L~F~lS-~p~~e~v~~AeLrl~~~~~~~~~~----~~~~~~~V~Vy~v~~~~~~~~~~~~~~~lL~~~---~~~~~g  178 (296)
T 4YCI_B          107 KHILIFNIS-IPRHEQITRAELRLYVSCQNDVDS----THGLEGSMVVYDVLEDSETWDQATGTKTFLVSQ---DIRDEG  178 (296)
T ss_dssp             EEEEECCCC-CCTTEEEEEEEEEEEEEECSCTTC----TTCCCEEEEEEEEEECCSSCSTTSSEEEEEEEE---EECSSE
T ss_pred             cEEEEEEEe-cCchhceEEEEEEEEeecCCCccC----CCCcEEEEEEEEeccccccccccCCcEEEEEEE---EcCCCe
Confidence            567899998 653 68999999999887643110    011245677776432100       01112222   234579


Q NP_000548.2     291 WEVFDIWKLFRNFKNSA----QLCLELEAW  316 (501)
Q Consensus       291 Wv~fDVT~aV~~Wl~~~----nlgL~V~~~  316 (501)
                      |+.||||.+|+.|+.++    +++|+|.+.
T Consensus       179 W~~fDVT~~V~~W~~~~~~~~~~gL~v~~~  208 (296)
T 4YCI_B          179 WETLEVSSAVKRWVRADSTTNKNKLEVTVQ  208 (296)
T ss_dssp             EEEEECHHHHHHHHSCTTSSCCSEEEEEEE
T ss_pred             eEEEEhHHHHHHHHHCCCCCCCceEEEEEE
Confidence            99999999999999985    478887664


No 49
>4NT5_A von Willebrand factor; cystine knot, dimerization of VWF; HET: SO4, NAG; 3.281A {Homo sapiens}
Probab=75.72  E-value=0.27  Score=37.97  Aligned_cols=65  Identities=22%  Similarity=0.456  Sum_probs=39.6  Template_Neff=7.800

Q NP_000548.2     422 LEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       422 ~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..+..++|.|.|......     +...  .      .....-.||.|.++....|...=.+|..  ..+.=+++.+|+|.
T Consensus        37 ~~v~~~~C~G~C~S~~~~-----~~~~--~------~~~~~c~CC~p~~~~~~~v~L~C~~g~~--~~~~~~~i~~C~C~  101 (107)
T 4NT5_A           37 VEVDIHYCQGKCASKAMY-----SIDI--N------DVQDQCSCCSPTRTEPMQVALHCTNGSV--VYHEVLNAMECKCS  101 (107)
T ss_dssp             SCEEEEECCCBCCEEEEE-----ETTT--T------EEEEEEEEEEESSEEEEEEEEECTTSCE--EEEEEEEECCEEEE
T ss_pred             eeeeceEEeEeecCceee-----cCCc--c------ceEeecCcccCeEeEeEEEEEECCCCCE--EEEEEEeeeeceEE
Confidence            567889999999875321     1100  0      0123578999999987776444333332  23344678899994


No 50
>2KD3_A Sclerostin; Protein, antagonist of CYTOKINE, PROTEIN; NMR {Mus musculus}
Probab=73.48  E-value=0.35  Score=38.01  Aligned_cols=73  Identities=15%  Similarity=0.291  Sum_probs=40.9  Template_Neff=6.600

Q NP_000548.2     419 IAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANN-VVYKQYEDMVVES  497 (501)
Q Consensus       419 iaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~-~~~~~~~~mvv~~  497 (501)
                      ++.+.+...+|.|.|.......   ...... ... .   ......||.|.++....|.+.=.+|. .+  ...-+.|.+
T Consensus        39 ~S~~~v~~~~C~G~C~s~s~~~---~~~~~~-~~~-~---~~~~c~CC~p~~t~~r~V~l~C~dG~~~~--~~~~~~V~~  108 (113)
T 2KD3_A           39 RSAKPVTELVCSGQCGPARLLP---NAIGRV-KWW-R---PNGPDFRCIPDRYRAQRVQLLCPGGAAPR--SRKVRLVAS  108 (113)
T ss_dssp             EECCCCCBCCCCCCCSCCCCCC---CCTTCC-SSS-C---SSCCCCCCEEEEEEEEEEEEECTTSEE------EEEEEEE
T ss_pred             eeCCccccceeeeeCCCCccCC---cccCCC-Ccc-c---ccCCCccccCceeEEEEEEEECCCCCeeE--EEEeEEEee
Confidence            4456678889999998653210   000000 000 0   12357899999999877655433342 22  334468899


Q NP_000548.2     498 CGCR  501 (501)
Q Consensus       498 CgC~  501 (501)
                      |+|.
T Consensus       109 C~C~  112 (113)
T 2KD3_A          109 CKCK  112 (113)
T ss_dssp             EECC
T ss_pred             cccC
Confidence            9994


No 51
>4YU8_A Neuroblastoma suppressor of tumorigenicity 1; BMP Binding Protein, NBL1 DAN; HET: NAG; 1.8A {Homo sapiens}
Probab=70.00  E-value=0.48  Score=38.53  Aligned_cols=88  Identities=13%  Similarity=0.121  Sum_probs=41.4  Template_Neff=7.100

Q NP_000548.2     398 ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISIL  477 (501)
Q Consensus       398 ~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~il  477 (501)
                      ..|....+...+..=|   - . +..+..++|.|.|.......    ...   ...    .....-.||.|.++....|-
T Consensus        32 ~~C~~~~~~~~I~~~g---C-~-s~~V~~~~C~G~C~S~s~~~----~~~---~~~----~~~~~CsCC~p~~~~~~~V~   95 (139)
T 4YU8_A           32 AWCEAKNITQIVGHSG---C-E-AKSIQNRACLGQCFSYSVPN----TFP---QST----ESLVHCDSCMPAQSMWEIVT   95 (139)
T ss_dssp             CEEEEEEEEEEECCTT---S-C-CEEEEEEEEEEECCC------------------------------EEEEEEEEEEEE
T ss_pred             CccEEEeeEEEEecCC---c-e-eeeeecceeeceecccccCC----CCC---CCc----cceeecCcccCeEEEEEEEE
Confidence            3566555444443211   1 2 25678899999998753210    000   000    01123469999999977664


Q NP_000548.2     478 FIDSANNV-VYKQYEDMVVESCGCR  501 (501)
Q Consensus       478 y~d~~~~~-~~~~~~~mvv~~CgC~  501 (501)
                      ..=.++.. ....+.=..+.+|+|.
T Consensus        96 L~C~~g~~~~~~~~~~~~v~sC~C~  120 (139)
T 4YU8_A           96 LECPGHEEVPRVDKLVEKILHCSCQ  120 (139)
T ss_dssp             EECTTCSSSCEEEEEEEEEEEEEEC
T ss_pred             EeCCCCCCcccEEEEEEeeeecccc
Confidence            33233322 0022333478999995


No 52
>2K8P_A Sclerostin; WNT SIGNALLING PATHWAY, BONE FORMATION; NMR {Homo sapiens}
Probab=66.67  E-value=0.66  Score=39.89  Aligned_cols=74  Identities=18%  Similarity=0.288  Sum_probs=43.0  Template_Neff=5.300

Q NP_000548.2     419 IAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESC  498 (501)
Q Consensus       419 iaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~C  498 (501)
                      .+.+.+...+|.|.|......    .+.. -......   ......||+|.+.....|-+.=.+|. ....+.-|+|.+|
T Consensus        71 ~S~kpV~~~~C~G~C~~~s~~----~~~~-~~~k~~~---~~~~~~CC~P~rTrtrrV~f~C~DGt-~t~~~~v~~V~sC  141 (189)
T 2K8P_A           71 RSAKPVTELVCSGQCGPARLL----PNAI-GRGKWWR---PSGPDFRCIPDRYRAQRVQLLCPGGE-APRARKVRLVASC  141 (189)
T ss_dssp             EESSCEEEEEECCCCCCCCCC----SSCC-CSSCCCS---CCCCCCCCEECCEEEEEEEEECCTTS-CCEEEEEEEECCE
T ss_pred             ecCCceeeeEEeeeCCCcccC----CCcc-cCCCccC---CCCCCCCCCCCeeEEEEEEEECCCCC-cceeEEeeEeeeC
Confidence            556777889999999864321    0100 0000001   12357899999988766655434342 0123345789999


Q NP_000548.2     499 GCR  501 (501)
Q Consensus       499 gC~  501 (501)
                      +|.
T Consensus       142 kCk  144 (189)
T 2K8P_A          142 KCK  144 (189)
T ss_dssp             ECC
T ss_pred             CCc
Confidence            994


No 53
>4JPH_D Gremlin-2; Cystine knot, DAN domain, CAN; HET: GSH, GOL, CIT; 2.25A {Mus musculus}
Probab=65.08  E-value=0.72  Score=37.91  Aligned_cols=88  Identities=14%  Similarity=0.239  Sum_probs=48.1  Template_Neff=6.700

Q NP_000548.2     398 ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISIL  477 (501)
Q Consensus       398 ~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~il  477 (501)
                      ..|....+...+..=|=    .+ ..+..++|.|.|.......    .......       ....-.||.|.++....|.
T Consensus        51 ~~C~~~~~~q~I~~~gC----~s-~~V~~~~C~G~C~S~s~p~----~~~~~~~-------~~~~CsCC~p~~~~~~~V~  114 (148)
T 4JPH_D           51 DWCKTQPLRQTVSEEGC----RS-RTILNRFCYGQCNSFYIPR----HVKKEED-------SFQSCAFCKPQRVTSVIVE  114 (148)
T ss_dssp             CEEEEEEEEEEECCTTS----CC-EEEEEEEEEEEEEEEEEEC----CCSSSCC-------EEEEEEEEEEEEEEEEEEE
T ss_pred             CceeeEeceEEEccCCc----ee-eeEEeceeeeecCcccccc----cCCCccc-------cccccCcccCeEEEEEEEE
Confidence            45776666555442221    22 4678899999998643210    0000000       1234689999999976664


Q NP_000548.2     478 FIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       478 y~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..=.++.-......=..|.+|+|.
T Consensus       115 L~C~~g~~~~~~~~v~~V~sC~C~  138 (148)
T 4JPH_D          115 LECPGLDPPFRIKKIQKVKHCRCM  138 (148)
T ss_dssp             ECCTTSSSSCEEEEEEEEEEEEEE
T ss_pred             EeCCCCCCCceEEEEEeeeeCcee
Confidence            332222211122334588999995


No 54
>4X1J_B Neuroblastoma suppressor of tumorigenicity 1; BMP antagonist, DAN family, Cystine-knot; HET: NAG; 2.5A {Homo sapiens}
Probab=64.18  E-value=0.74  Score=35.85  Aligned_cols=88  Identities=13%  Similarity=0.131  Sum_probs=46.1  Template_Neff=7.700

Q NP_000548.2     398 ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISIL  477 (501)
Q Consensus       398 ~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~il  477 (501)
                      ..|....+...+..=|=     .+..+..++|.|.|.......    ...   ...    .....-.||.|.++....|.
T Consensus        17 ~~C~~~~~~~~i~~~gC-----~s~~i~~~~C~G~C~S~~~~~----~~~---~~~----~~~~~C~CC~p~~~~~~~V~   80 (116)
T 4X1J_B           17 AWCEAKNITQIVGHSGC-----EAKSIQNRACLGQCFSYSVPN----TFP---QST----ESLVHCDSCMPAQSMWEIVT   80 (116)
T ss_dssp             CEEEEEEEEEEECCTTS-----CCEEEEEEEEEEEEEEEECC------------------CTTEEEEEEEEEEEEEEEEE
T ss_pred             CccEEEEeEEEEccCCc-----cceeEecceEeeeeeeeeecC----CCC---CCC----cceeecCCccceEEEEEEEE
Confidence            35666555444432111     123578899999998643210    000   000    01234579999999987764


Q NP_000548.2     478 FIDSANNV-VYKQYEDMVVESCGCR  501 (501)
Q Consensus       478 y~d~~~~~-~~~~~~~mvv~~CgC~  501 (501)
                      ..=.++.- ......=.++.+|+|.
T Consensus        81 L~C~~g~~~~~~~~~~~~v~~C~C~  105 (116)
T 4X1J_B           81 LECPGHEEVPRVDKLVEKILHCSCQ  105 (116)
T ss_dssp             EECTTCSSSSEEEEEEEEEEEEEEE
T ss_pred             EECCCCCCCccEEEEEEeeEecccc
Confidence            43233322 1122333478999995


No 55
>5AEJ_A GREMLIN-1; SIGNALING PROTEIN, SIGNALING, GREMLIN, GROWTH; HET: SO4; 1.904A {HOMO SAPIENS}
Probab=62.64  E-value=0.87  Score=37.64  Aligned_cols=87  Identities=15%  Similarity=0.248  Sum_probs=48.6  Template_Neff=6.100

Q NP_000548.2     397 KARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISI  476 (501)
Q Consensus       397 ~~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~i  476 (501)
                      ...|....+...+..=|=    . +..+..++|.|.|......     ... . ..   . .....-.||.|.++....|
T Consensus        59 ~~~C~~~~~~q~I~~~gC----~-S~~V~~~~C~G~C~S~s~p-----s~~-~-~~---~-~~~~~CsCC~p~~s~~~~V  122 (152)
T 5AEJ_A           59 RDWCKTQPLKQTIHEEGC----N-SRTIINRFCYGQCNSFYIP-----RHI-R-KE---E-GSFQSCSFCKPKKFTTMMV  122 (152)
T ss_dssp             CCEEEEEEEEEEECCTTS----C-CEEEEEEEEEEEEEEEEEE-----EEE-T-TE---E-EEEEEEEEEEEEEEEEEEE
T ss_pred             CCceeeeeceeEEccCCc----e-eceEEeeeceeecccCeec-----ccc-c-cc---C-CceeecCcccceEEEEEEE
Confidence            456877766555542221    2 2568899999999864321     100 0 00   0 0122467999999987666


Q NP_000548.2     477 LFIDSANNV--VYKQYEDMVVESCGCR  501 (501)
Q Consensus       477 ly~d~~~~~--~~~~~~~mvv~~CgC~  501 (501)
                      ...=.++..  +.+.+  ..+.+|.|.
T Consensus       123 ~L~Cpdg~~~~~~~~v--~~V~sC~C~  147 (152)
T 5AEJ_A          123 TLNCPELQPPTKKKRV--TRVKQCRCI  147 (152)
T ss_dssp             EEECTTSSSSEEEEEE--EEEEEEEEE
T ss_pred             EEECCCCCCCceEEEE--EeceeceeE
Confidence            333222322  23333  578999995


No 56
>5HK5_G Gremlin-2, Growth/differentiation factor 5; DAN-family, Bone Morphogenetic Proteins, CYTOKINE; 2.9A {Mus musculus}
Probab=61.90  E-value=0.91  Score=37.23  Aligned_cols=86  Identities=15%  Similarity=0.240  Sum_probs=46.5  Template_Neff=6.600

Q NP_000548.2     398 ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISIL  477 (501)
Q Consensus       398 ~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~il  477 (501)
                      ..|....+...+..=|=    .+ ..+..++|.|.|.......    .......       ....-.||.|.++....|.
T Consensus        50 ~~C~~~~~~q~I~~~gC----~s-~~V~~~~C~G~C~S~s~ps----~~~~~~~-------~~~~CsCC~p~~~~~~~V~  113 (147)
T 5HK5_G           50 DWCKTQPLRQTVSEEGC----RS-RTILNRFCYGQCNSFYIPR----HVKKEED-------SFQSCAFCKPQRVTSVIVE  113 (147)
T ss_pred             CceeeEeceEEEccCCc----ee-eeEEeceeeeecCcccccc----cCCCccc-------cccccCcccCeEEEEEEEE
Confidence            35665555544432121    22 4578899999998643210    0000000       1234679999999976663


Q NP_000548.2     478 FIDSANNV--VYKQYEDMVVESCGCR  501 (501)
Q Consensus       478 y~d~~~~~--~~~~~~~mvv~~CgC~  501 (501)
                      ..=.++..  +.+.  =.+|.+|+|.
T Consensus       114 L~C~dg~~~~~~~~--~~~V~sC~C~  137 (147)
T 5HK5_G          114 LECPGLDPPFRIKK--IQKVKHCRCM  137 (147)
T ss_pred             EeCCCCCCCceEEE--EEeeeeCcee
Confidence            33222221  2333  3578999994


No 57
>5BPU_A Frizzled-4; Wnt signalling pathway, Norrie disease; HET: GGL; 2.4A {Homo sapiens}
Probab=57.82  E-value=1.2  Score=34.98  Aligned_cols=72  Identities=21%  Similarity=0.280  Sum_probs=38.3  Template_Neff=7.700

Q NP_000548.2     422 LEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISILFIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       422 ~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~ily~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..+..++|.|.|.......    ........  ........-.||.|.++....+...=.++..+.  ..-.++.+|.|.
T Consensus        37 ~~v~~~~C~G~C~S~~~~~----p~~~~~~~--~~~~~~~~C~CC~p~~~~~~~v~l~C~~g~~~~--~~~~~i~~C~C~  108 (122)
T 5BPU_A           37 KMVLLARCEGHCSQASRSE----PLVSFSTV--LKQPFRSSCHCCRPQTSKLKALRLRCSGGMRLT--ATYRYILSCHCE  108 (122)
T ss_pred             CcEeceeeeccccceeecC----CCcccCCC--CCCcceeeeecCcCeEeEEEEEEEECCCCCeEE--EEEEEEEeceee
Confidence            6678899999998753200    00000000  000012345899999988766533323332222  333478899994


No 58
>5BQ8_C Norrin; Wnt signalling pathway, Norrie disease; HET: MLY; 2.0A {Homo sapiens}
Probab=53.96  E-value=1.5  Score=34.27  Aligned_cols=93  Identities=19%  Similarity=0.268  Sum_probs=46.5  Template_Neff=7.800

Q NP_000548.2     398 ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISIL  477 (501)
Q Consensus       398 ~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~il  477 (501)
                      ..|....+...+..=.. .- .. ..+..++|.|.|.......    ........  ........-.||.|.++....|.
T Consensus        16 ~~C~~~~~~~~i~~~~~-gC-~s-~~v~~~~C~G~C~S~~~~~----p~~~~~~~--~~~~~~~~C~CC~p~~~~~~~V~   86 (122)
T 5BQ8_C           16 RRCMRHHYVDSISHPLY-KC-SS-KMVLLARCEGHCSQASRSE----PLVSFSTV--LKQPFRSSCHCCRPQTSKLKALR   86 (122)
T ss_dssp             TSSEEEEEEEEECCSSS-CB-CC-EEEEEEEEEECCSSCEEEE----ECCEETTB--CCCSEEEECEEEEEEEEEEEEEE
T ss_pred             CCeEEEeeEEEEEcCCC-Cc-ee-ceeEeeeEEEecccceecC----CccccCCC--CCCCceeEceecCCeEeEEEEEE
Confidence            45666555444432100 11 22 6678899999998753200    00000000  00001234589999998876653


Q NP_000548.2     478 FIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       478 y~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..=.++..+  ...-+++.+|.|.
T Consensus        87 l~C~~g~~~--~~~~~~i~~C~C~  108 (122)
T 5BQ8_C           87 LRCSGGMRL--TATYRYILSCHCE  108 (122)
T ss_dssp             EEETTTEEE--EEEEEEEEEEEEE
T ss_pred             EECCCCceE--EEEEEEEEeceee
Confidence            332333322  2334578999994


No 59
>5BQE_A Frizzled-4; Wnt signalling pathway, Norrie disease; HET: MLY, NAG, PG0; 2.3A {Homo sapiens}
Probab=53.96  E-value=1.5  Score=34.27  Aligned_cols=93  Identities=19%  Similarity=0.268  Sum_probs=46.5  Template_Neff=7.800

Q NP_000548.2     398 ARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLCEFPLRSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISIL  477 (501)
Q Consensus       398 ~~Cc~~~l~V~F~dlGW~~wIiaP~~~~a~yC~G~C~~~~~~~~~~~~h~~i~~~~~~~~~~~~~~pCC~P~~~~~l~il  477 (501)
                      ..|....+...+..=.. .- .. ..+..++|.|.|.......    ........  ........-.||.|.++....|.
T Consensus        16 ~~C~~~~~~~~i~~~~~-gC-~s-~~v~~~~C~G~C~S~~~~~----p~~~~~~~--~~~~~~~~C~CC~p~~~~~~~V~   86 (122)
T 5BQE_A           16 RRCMRHHYVDSISHPLY-KC-SS-KMVLLARCEGHCSQASRSE----PLVSFSTV--LKQPFRSSCHCCRPQTSKLKALR   86 (122)
T ss_dssp             TSSEEEEEEEEECCSSS-CB-CC-EEEEEEEEEECCSSCEEEE----ECCBCSSS--CSSCEEEECEEEEEEEEEEEEEE
T ss_pred             CCeEEEeeEEEEEcCCC-Cc-ee-ceeEeeeEEEecccceecC----CccccCCC--CCCCceeEceecCCeEeEEEEEE
Confidence            45666555444432100 11 22 6678899999998753200    00000000  00001234589999998876653


Q NP_000548.2     478 FIDSANNVVYKQYEDMVVESCGCR  501 (501)
Q Consensus       478 y~d~~~~~~~~~~~~mvv~~CgC~  501 (501)
                      ..=.++..+  ...-+++.+|.|.
T Consensus        87 l~C~~g~~~--~~~~~~i~~C~C~  108 (122)
T 5BQE_A           87 LRCSGGMRL--TATYRYILSCHCE  108 (122)
T ss_dssp             EEBSSSCEE--EEEEEEEEEEEEE
T ss_pred             EECCCCceE--EEEEEEEEeceee
Confidence            332333322  2334578999994


Query         NP_000836.2
Match_columns 908
No_of_seqs    3628 out of 54127
Neff          10.7604
Searched_HMMs 7012
Date          Sun Jul 26 14:02:06 2020
Command       /home/guerler/hh-suite/build/bin/hhblits -i /home/guerler/human/fasta/NP_00/NP_000836.2.fasta -d /home/guerler/pdb70/pdb70 -o /home/guerler/human/hhr/NP_00/NP_000836.2.hhr 

 No Hit                             Prob E-value P-value  Score    SS Cols Query HMM  Template HMM
  1 6N4X_A Metabotropic glutamate  100.0 2.5E-77 1.8E-81  724.0   0.0  801   35-855    30-845 (877)
  2 6N52_B Metabotropic glutamate  100.0 1.2E-76 8.4E-81  718.1   0.0  803   34-856    29-846 (871)
  3 6N51_B Metabotropic glutamate  100.0 6.7E-76 4.8E-80  706.5   0.0  786   37-842     4-804 (804)
  4 6W2Y_A Gamma-aminobutyric acid 100.0 3.8E-66 2.8E-70  620.7   0.0  685   36-853    22-734 (829)
  5 6W2X_B Gamma-aminobutyric acid 100.0 8.6E-65 6.2E-69  611.4   0.0  678   36-852    13-725 (908)
  6 6UO8_A Gamma-aminobutyric acid 100.0 9.3E-65 6.7E-69  605.5   0.0  682   42-856     3-712 (762)
  7 6UO8_B Gamma-aminobutyric acid 100.0 2.2E-64 1.6E-68  602.9   0.0  675   39-852     9-718 (779)
  8 7C7Q_A Gamma-aminobutyric acid 100.0 3.4E-62 2.5E-66  592.4   0.0  685   40-855   166-876 (879)
  9 2E4U_A Metabotropic glutamate  100.0 1.2E-43 8.6E-48  406.8   0.0  535   40-584     9-553 (555)
 10 2E4X_B Metabotropic glutamate  100.0 1.2E-43 8.6E-48  406.8   0.0  535   40-584     9-553 (555)
 11 6N50_A Metabotropic glutamate  100.0 4.1E-43   3E-47  405.6   0.0  536   36-576    42-589 (596)
 12 6N4Y_C Metabotropic glutamate  100.0 4.4E-43 3.2E-47  405.3   0.0  536   36-576    42-589 (596)
 13 5K5S_B Extracellular calcium-s 100.0 1.3E-42 9.6E-47  402.9   0.0  534   39-580    25-609 (615)
 14 5KZQ_A Metabotropic glutamate  100.0 1.7E-42 1.2E-46  398.2   0.0  529   38-580    24-564 (570)
 15 5K5T_A Extracellular calcium-s 100.0 2.4E-42 1.8E-46  400.9   0.0  534   39-580    25-609 (615)
 16 6FFH_A Metabotropic glutamate  100.0 9.6E-38 6.9E-42  309.0   0.0  266  573-852     4-431 (444)
 17 6FFI_A Metabotropic glutamate  100.0 9.6E-38 6.9E-42  309.0   0.0  266  573-852     4-431 (444)
 18 4OR2_B Chimera of Soluble cyto 100.0 1.8E-37 1.3E-41  330.2   0.0  271  570-854   108-380 (389)
 19 6BT5_B Metabotropic glutamate   99.9 2.3E-27 1.7E-31  265.1   0.0  468   40-507     4-471 (479)
 20 6BSZ_A Metabotropic glutamate   99.9 3.3E-27 2.4E-31  263.8   0.0  468   40-507     4-471 (479)
 21 3KS9_B Metabotropic glutamate   99.8 1.4E-26   1E-30  259.8   0.0  465   37-506     9-489 (496)
 22 4XAR_A Metabotropic glutamate   99.8 1.6E-26 1.2E-30  260.6   0.0  462   37-506    32-503 (517)
 23 6B7H_A Metabotropic glutamate   99.8 1.6E-26 1.2E-30  260.6   0.0  462   37-506    32-503 (517)
 24 1EWK_B METABOTROPIC GLUTAMATE   99.8 1.8E-26 1.3E-30  258.4   0.0  464   38-506     5-484 (490)
 25 1EWT_A METABOTROPIC GLUTAMATE   99.8 1.8E-26 1.3E-30  258.4   0.0  464   38-506     5-484 (490)
 26 5C5C_A Metabotropic glutamate   99.8   2E-26 1.4E-30  257.7   0.0  468   38-505     9-480 (481)
 27 3SM9_A Metabotropic glutamate   99.8 2.4E-26 1.7E-30  256.8   0.0  459   40-506     8-476 (479)
 28 4XAQ_A Metabotropic glutamate   99.8 9.3E-26 6.8E-30  253.4   0.0  453   40-506    28-491 (503)
 29 5CNI_A Metabotropic glutamate   99.8 9.3E-26 6.8E-30  253.4   0.0  453   40-506    28-491 (503)
 30 5CNJ_A Metabotropic glutamate   99.8 1.1E-25 7.8E-30  252.8   0.0  454   39-506    27-491 (503)
 31 5FBK_A Extracellular calcium-s  99.8 3.8E-25 2.8E-29  252.0   0.0  460   40-507    53-560 (568)
 32 5FBK_B Extracellular calcium-s  99.8 4.7E-25 3.4E-29  251.3   0.0  460   40-507    53-560 (568)
 33 1DP4_A ATRIAL NATRIURETIC PEPT  99.8 2.8E-24   2E-28  236.6   0.0  369   44-494     1-397 (435)
 34 1DP4_C ATRIAL NATRIURETIC PEPT  99.8 2.8E-24   2E-28  236.6   0.0  369   44-494     1-397 (435)
 35 5X2M_A Taste receptor, type 1,  99.8 4.3E-24 3.1E-28  237.0   0.0  419   35-494     4-432 (461)
 36 5X2N_C Taste receptor, type 1,  99.8 4.3E-24 3.1E-28  237.0   0.0  419   35-494     4-432 (461)
 37 5X2M_B Taste receptor, type 1,  99.8 1.5E-23 1.1E-27  233.8   0.0  440   39-512    12-470 (478)
 38 5X2N_B Taste receptor, type 1,  99.8 1.5E-23 1.1E-27  233.8   0.0  440   39-512    12-470 (478)
 39 5X2N_D Taste receptor, type 1,  99.8 1.5E-23 1.1E-27  233.8   0.0  440   39-512    12-470 (478)
 40 1JDN_A ATRIAL NATRIURETIC PEPT  99.8   2E-23 1.4E-27  230.1   0.0  372   41-494     5-395 (441)
 41 1JDP_A ATRIAL NATRIURETIC PEPT  99.8   2E-23 1.4E-27  230.1   0.0  372   41-494     5-395 (441)
 42 4F11_A Gamma-aminobutyric acid  99.7   2E-22 1.4E-26  221.5   0.0  391   39-506     8-419 (433)
 43 4MS4_B Gamma-aminobutyric acid  99.7   2E-22 1.4E-26  221.5   0.0  391   39-506     8-419 (433)
 44 4MQE_A Gamma-aminobutyric acid  99.7   2E-21 1.4E-25  212.4   0.0  376   43-494     3-392 (420)
 45 4MS4_A Gamma-aminobutyric acid  99.7   2E-21 1.4E-25  212.4   0.0  376   43-494     3-392 (420)
 46 3Q41_C Glutamate [NMDA] recept  99.7 4.8E-21 3.4E-25  206.5   0.0  348   42-507     3-364 (384)
 47 5KC8_A Glutamate receptor iono  99.6 9.9E-21 7.1E-25  207.4   0.0  378   42-495     3-403 (429)
 48 3OM0_A Glutamate receptor, ion  99.6 2.1E-20 1.5E-24  201.9   0.0  370   43-495     2-376 (393)
 49 3QLU_B Glutamate receptor, ion  99.6 2.1E-20 1.5E-24  201.9   0.0  370   43-495     2-376 (393)
 50 5FWY_B GLUTAMATE RECEPTOR 2, G  99.6 2.4E-20 1.7E-24  201.4   0.0  372   43-505     3-385 (390)
 51 6FPJ_A Glutamate receptor 3; l  99.6 2.4E-20 1.7E-24  201.4   0.0  372   43-505     3-385 (390)
 52 3H5L_A putative Branched-chain  99.6 2.8E-20 2.1E-24  203.0   0.0  363   40-493     9-385 (419)
 53 3H5L_B putative Branched-chain  99.6 2.8E-20 2.1E-24  203.0   0.0  363   40-493     9-385 (419)
 54 5KCA_A Cerebellin-1,Cerebellin  99.6 4.6E-20 3.3E-24  221.1   0.0  382   40-496   452-855 (878)
 55 4XFK_A BrovA.17370.a; transpor  99.6 5.4E-20 3.9E-24  199.1   0.0  355   43-493     9-374 (399)
 56 5KC9_A Glutamate receptor iono  99.6 5.6E-20 4.1E-24  201.2   0.0  372   42-495     3-402 (428)
 57 6JFY_A Glutamate receptor iono  99.6 1.1E-19 7.8E-24  216.7   0.0  373   43-494     2-380 (809)
 58 4GPA_A Glutamate receptor 4; P  99.6 1.1E-19 7.9E-24  196.1   0.0  361   43-496     3-374 (389)
 59 5EWM_A NMDA glutamate receptor  99.6 1.2E-19 8.4E-24  195.9   0.0  351   43-507     2-383 (390)
 60 3H6G_A Glutamate receptor, ion  99.6 1.2E-19 8.7E-24  196.1   0.0  373   43-495     2-378 (395)
 61 3H6G_B Glutamate receptor, ion  99.6 1.2E-19 8.7E-24  196.1   0.0  373   43-495     2-378 (395)
 62 6JFY_B Glutamate receptor iono  99.6 1.2E-19 8.9E-24  216.1   0.0  373   43-494     2-380 (809)
 63 5L2E_B Cerebellin-1; Synapse P  99.6 1.3E-19 9.3E-24  211.8   0.0  379   42-495     2-402 (688)
 64 3QEK_B NMDA glutamate receptor  99.6 1.3E-19 9.4E-24  195.1   0.0  349   43-505     3-382 (384)
 65 6LU9_D Glutamate receptor iono  99.6 1.3E-19 9.6E-24  218.0   0.0  374   44-494     2-399 (877)
 66 1USG_A LEUCINE-SPECIFIC BINDIN  99.6 2.1E-19 1.5E-23  190.1   0.0  335   44-477     1-337 (346)
 67 3IP6_A ABC transporter, substr  99.6 2.6E-19 1.9E-23  190.4   0.0  349   44-493     1-351 (356)
 68 3IPC_A ABC transporter, substr  99.6 2.7E-19   2E-23  190.1   0.0  348   45-493     2-351 (356)
 69 4EYG_B Twin-arginine transloca  99.5 3.1E-19 2.3E-23  190.7   0.0  356   42-494     3-360 (368)
 70 4EYK_A Twin-arginine transloca  99.5 3.1E-19 2.3E-23  190.7   0.0  356   42-494     3-360 (368)
 71 3HUT_A putative branched-chain  99.5   4E-19 2.9E-23  189.0   0.0  350   43-493     2-353 (358)
 72 5KUH_C Glutamate receptor iono  99.5 4.1E-19   3E-23  210.0   0.0  372   43-495     2-378 (757)
 73 4EVQ_A Putative ABC transporte  99.5 4.1E-19   3E-23  190.4   0.0  352   39-491    10-361 (375)
 74 4EVQ_B Putative ABC transporte  99.5 4.1E-19   3E-23  190.4   0.0  352   39-491    10-361 (375)
 75 4N0Q_B Leu/Ile/Val-binding pro  99.5 4.2E-19   3E-23  188.6   0.0  336   43-477     8-346 (354)
 76 4N0Q_C Leu/Ile/Val-binding pro  99.5 4.2E-19   3E-23  188.6   0.0  336   43-477     8-346 (354)
 77 3SAJ_C Glutamate receptor 1; R  99.5 4.5E-19 3.3E-23  190.7   0.0  357   41-495     6-372 (384)
 78 6E7R_B Glutamate receptor iono  99.5   6E-19 4.4E-23  188.1   0.0  348   44-505     2-361 (363)
 79 6E7S_D Glutamate receptor iono  99.5   6E-19 4.4E-23  188.1   0.0  348   44-505     2-361 (363)
 80 3HSY_B Glutamate receptor 2; G  99.5 6.1E-19 4.5E-23  188.9   0.0  357   44-495     1-369 (376)
 81 3SAJ_B Glutamate receptor 1; R  99.5 6.5E-19 4.7E-23  189.5   0.0  357   41-495     6-372 (384)
 82 3N6V_D Glutamate receptor 2; A  99.5 6.9E-19   5E-23  188.4   0.0  355   46-495     1-367 (374)
 83 4GNR_A ABC transporter substra  99.5   7E-19 5.1E-23  186.7   0.0  347   41-492     3-352 (353)
 84 3N0X_A Possible substrate bind  99.5 7.4E-19 5.3E-23  188.3   0.0  348   43-494     2-355 (374)
 85 6KSP_B Glutamate receptor iono  99.5 7.5E-19 5.4E-23  210.7   0.0  372   44-494     2-398 (856)
 86 3N6V_B Glutamate receptor 2; A  99.5 8.3E-19   6E-23  187.8   0.0  355   46-495     1-367 (374)
 87 1Z17_A Leu/Ile/Val-binding pro  99.5 8.4E-19 6.1E-23  185.2   0.0  333   45-478     2-336 (344)
 88 4RU0_B Putative branched-chain  99.5   1E-18 7.4E-23  192.3   0.0  370   40-494    28-416 (447)
 89 5EWM_D NMDA glutamate receptor  99.5   1E-18 7.5E-23  186.3   0.0  349   43-505     2-362 (364)
 90 4MLC_A Extracellular ligand-bi  99.5 1.1E-18 7.8E-23  185.4   0.0  346   40-489     5-355 (356)
 91 4Q6B_A Extracellular ligand-bi  99.5 1.1E-18 7.8E-23  185.4   0.0  346   40-489     5-355 (356)
 92 3TD9_A Branched chain amino ac  99.5 1.1E-18 8.1E-23  186.2   0.0  347   43-494    14-363 (366)
 93 3N0W_B ABC branched chain amin  99.5 1.7E-18 1.2E-22  185.8   0.0  350   42-493     3-354 (379)
 94 1PEA_A AMIDASE OPERON, ACETAMI  99.5 1.8E-18 1.3E-22  186.1   0.0  354   42-493     4-359 (385)
 95 1QO0_B AMIC, AMIR; BINDING PRO  99.5 1.8E-18 1.3E-22  186.1   0.0  354   42-493     4-359 (385)
 96 4KV7_A Probable leucine/isoleu  99.5 1.9E-18 1.4E-22  185.5   0.0  349   38-477    10-366 (381)
 97 4OBB_B Amino acid/amide ABC tr  99.5   2E-18 1.5E-22  186.4   0.0  362   39-492    27-392 (395)
 98 4RV5_B Amino acid/amide ABC tr  99.5   2E-18 1.5E-22  186.4   0.0  362   39-492    27-392 (395)
 99 3I45_A Twin-arginine transloca  99.5 2.3E-18 1.6E-22  185.4   0.0  355   43-494     3-360 (387)
100 4F06_A Extracellular ligand-bi  99.5 2.9E-18 2.1E-22  183.2   0.0  356   42-492     2-361 (371)
101 4N03_A ABC-type branched-chain  99.5 4.8E-18 3.5E-22  184.1   0.0  356   40-494    28-392 (405)
102 4M88_A Extracellular ligand-bi  99.5 4.9E-18 3.5E-22  180.4   0.0  343   43-477     2-350 (357)
103 3I09_B Periplasmic branched-ch  99.5 6.2E-18 4.5E-22  181.0   0.0  347   43-492     2-349 (375)
104 5TQ0_B NMDA glutamate receptor  99.4 6.5E-18 4.7E-22  179.7   0.0  343   46-505     1-358 (360)
105 5TPW_B NMDA glutamate receptor  99.4 6.5E-18 4.7E-22  179.7   0.0  343   46-505     1-358 (360)
106 4MAA_A Putative branched-chain  99.4 9.1E-18 6.6E-22  181.7   0.0  352   40-494    29-383 (403)
107 5L1B_D Glutamate receptor 2; T  99.4 1.1E-17 8.2E-22  198.8   0.0  356   44-494     1-368 (803)
108 4TLL_D GluN1/GluN2B; Neurotran  99.4 1.3E-17 9.1E-22  199.0   0.0  340   40-494     5-358 (824)
109 4TLM_D GluN1/GluN2B; neurotran  99.4 1.3E-17 9.1E-22  199.0   0.0  340   40-494     5-358 (824)
110 4EYQ_A Extracellular ligand-bi  99.4 1.8E-17 1.3E-21  176.2   0.0  348   41-477     3-354 (362)
111 3LKB_B Probable branched-chain  99.4 1.9E-17 1.4E-21  178.4   0.0  360   42-494     4-375 (392)
112 4F8J_A Putative branched-chain  99.4 2.8E-17   2E-21  174.7   0.0  348   41-477     3-354 (362)
113 4U4G_D GluA2*; Ionotropic glut  99.4 2.9E-17 2.1E-21  195.8   0.0  356   44-494     1-368 (822)
114 6PEQ_D Glutamate receptor 2, P  99.4 3.4E-17 2.4E-21  196.9   0.0  360   40-494    21-392 (889)
115 3UK0_A Extracellular ligand-bi  99.4 3.5E-17 2.6E-21  173.9   0.0  348   41-477     3-354 (362)
116 4TLL_C GluN1/GluN2B; Neurotran  99.4 3.6E-17 2.6E-21  194.8   0.0  349   43-507     3-363 (823)
117 4TLM_C GluN1/GluN2B; neurotran  99.4 3.6E-17 2.6E-21  194.8   0.0  349   43-507     3-363 (823)
118 4MPT_B Putative leu/ile/val-bi  99.4 3.6E-17 2.6E-21  175.3   0.0  354   42-477     3-367 (380)
119 4ZPJ_A Extracellular ligand-bi  99.4 5.1E-17 3.7E-21  177.0   0.0  346   39-476    48-399 (423)
120 6DLZ_B Glutamate receptor 2,Vo  99.4 5.2E-17 3.7E-21  198.5   0.0  356   44-494     1-368 (1031)
121 3EAF_A ABC transporter, substr  99.4 6.6E-17 4.8E-21  174.0   0.0  362   43-494     2-372 (391)
122 5UOW_C N-methyl-D-aspartate re  99.4 6.8E-17 4.9E-21  192.2   0.0  336   43-494     2-348 (814)
123 3LOP_A Substrate binding perip  99.4 7.1E-17 5.1E-21  171.9   0.0  352   43-492     3-360 (364)
124 5IOV_B GluN1, GLY-GLY-GLU-GLU;  99.4 7.4E-17 5.4E-21  192.2   0.0  341   39-494    23-377 (825)
125 5WEO_A Glutamate receptor 2,Vo  99.3 1.3E-16 9.5E-21  195.0   0.0  356   44-494     1-368 (1034)
126 4DQD_A Extracellular ligand-bi  99.3 1.9E-16 1.4E-20  168.3   0.0  348   43-477     2-355 (363)
127 3SG0_A Extracellular ligand-bi  99.3 3.9E-16 2.8E-20  167.4   0.0  350   41-477    23-378 (386)
128 5ERE_A Extracellular ligand-bi  99.3 4.6E-16 3.3E-20  176.6   0.0  327   45-494     1-327 (568)
129 3CKM_A Uncharacterized protein  99.2 3.7E-15 2.7E-19  155.6   0.0  322   44-493     1-324 (327)
130 5VBG_A Penicillin-binding prot  98.9 1.6E-13 1.2E-17  154.3   0.0  215   40-311   219-434 (543)
131 5KCN_A Penicillin-binding prot  98.9 1.6E-13 1.2E-17  154.2   0.0  215   40-311   219-434 (543)
132 4PYR_A Putative branched-chain  98.9 1.7E-13 1.2E-17  141.2   0.0  204   45-311     1-205 (305)
133 4YLE_A Simple sugar transport   97.8 1.5E-08 1.1E-12  103.5   0.0  224   40-308    27-256 (316)
134 4RK1_B Ribose transcriptional   97.7 2.9E-08 2.1E-12   99.2   0.0  204   42-300     4-209 (280)
135 4RK1_D Ribose transcriptional   97.7 2.9E-08 2.1E-12   99.2   0.0  204   42-300     4-209 (280)
136 3BRQ_A HTH-type transcriptiona  97.6 3.8E-08 2.7E-12   99.3   0.0  208   41-300    15-225 (296)
137 3BRQ_B HTH-type transcriptiona  97.6 3.8E-08 2.7E-12   99.3   0.0  208   41-300    15-225 (296)
138 5DTE_B Monosaccharide-transpor  97.6 5.2E-08 3.8E-12   99.3   0.0  222   41-308    22-249 (311)
139 3KSM_B ABC-type sugar transpor  97.6 5.5E-08   4E-12   96.9   0.0  212   46-308     1-220 (276)
140 3KSM_A ABC-type sugar transpor  97.6 5.5E-08   4E-12   96.9   0.0  212   46-308     1-220 (276)
141 4RSM_A Periplasmic binding pro  97.6 5.6E-08 4.1E-12   99.9   0.0  213   40-308     7-226 (327)
142 6HBD_B ABC transporter peripla  97.6 5.7E-08 4.1E-12   99.4   0.0  211   39-300    11-230 (320)
143 4JOQ_A ABC ribose transporter,  97.6 6.4E-08 4.6E-12   97.7   0.0  218   42-308     4-226 (297)
144 4JOQ_B ABC ribose transporter,  97.6 6.4E-08 4.6E-12   97.7   0.0  218   42-308     4-226 (297)
145 5HSG_A Putative ABC transporte  97.5   7E-08 5.1E-12   98.2   0.0  214   41-308    21-243 (310)
146 2O20_B Catabolite control prot  97.5 8.3E-08   6E-12   98.8   0.0  203   42-300    60-264 (332)
147 2O20_F Catabolite control prot  97.5 8.3E-08   6E-12   98.8   0.0  203   42-300    60-264 (332)
148 4YO7_A Sugar ABC transporter (  97.5 8.5E-08 6.2E-12   98.4   0.0  216   40-308    40-261 (326)
149 6GQ0_A Putative sugar binding   97.5 9.5E-08 6.9E-12   97.6   0.0  220   35-308    20-246 (318)
150 6GT9_C Putative sugar binding   97.5 9.5E-08 6.9E-12   97.6   0.0  220   35-308    20-246 (318)
151 1GUB_A D-ALLOSE-BINDING PERIPL  97.5   1E-07 7.3E-12   95.6   0.0  218   45-308     1-226 (288)
152 1GUD_B D-ALLOSE-BINDING PERIPL  97.5   1E-07 7.3E-12   95.6   0.0  218   45-308     1-226 (288)
153 1DBQ_B PURINE REPRESSOR; TRANS  97.5 1.1E-07 7.8E-12   95.4   0.0  205   42-300     4-212 (289)
154 4RK0_D LacI family sugar-bindi  97.5 1.2E-07 8.7E-12   94.2   0.0  198   42-300     4-203 (274)
155 3DBI_A SUGAR-BINDING TRANSCRIP  97.4 1.3E-07 9.1E-12   97.6   0.0  207   42-300    58-267 (338)
156 3DBI_C SUGAR-BINDING TRANSCRIP  97.4 1.3E-07 9.1E-12   97.6   0.0  207   42-300    58-267 (338)
157 3EGC_F putative ribose operon   97.4 1.5E-07 1.1E-11   94.6   0.0  205   41-300     4-211 (291)
158 4KZK_A L-arabinose-binding pro  97.4 1.6E-07 1.1E-11   96.8   0.0  218   40-308    31-265 (337)
159 3O1I_C Sensor protein TorS (E.  97.4 1.6E-07 1.1E-11   95.1   0.0  216   43-308     3-226 (304)
160 3O1I_D Sensor protein TorS (E.  97.4 1.6E-07 1.1E-11   95.1   0.0  216   43-308     3-226 (304)
161 3O1J_C Sensor protein TorS (E.  97.4 1.6E-07 1.1E-11   95.1   0.0  216   43-308     3-226 (304)
162 4YHS_A ABC TRANSPORTER SOLUTE   97.4 1.6E-07 1.1E-11   97.7   0.0  215   40-308    53-276 (354)
163 3CLK_B Transcription regulator  97.4 1.6E-07 1.2E-11   94.3   0.0  205   41-300     4-210 (290)
164 2RGY_A Transcriptional regulat  97.4 1.6E-07 1.2E-11   94.2   0.0  208   41-300     4-214 (290)
165 6HB0_A ABC transporter peripla  97.4 1.8E-07 1.3E-11   95.7   0.0  211   39-300    13-232 (322)
166 1SXG_D Glucose-resistance amyl  97.4 1.8E-07 1.3E-11   93.2   0.0  204   42-300     5-212 (280)
167 2NZV_G Catabolite control prot  97.4 1.8E-07 1.3E-11   93.2   0.0  204   42-300     5-212 (280)
168 4RS3_A ABC transporter, carboh  97.4 1.9E-07 1.4E-11   95.7   0.0  213   40-308     7-226 (327)
169 5OCP_A Periplasmic binding pro  97.4   2E-07 1.5E-11   94.3   0.0  203   47-300     2-212 (302)
170 3BIL_A Probable LacI-family tr  97.4 2.1E-07 1.5E-11   96.4   0.0  202   42-300    63-266 (348)
171 3O74_A Fructose transport syst  97.3 2.3E-07 1.6E-11   91.9   0.0  200   45-300     2-205 (272)
172 3O74_B Fructose transport syst  97.3 2.3E-07 1.6E-11   91.9   0.0  200   45-300     2-205 (272)
173 4Z0N_A Periplasmic Solute Bind  97.3 2.3E-07 1.7E-11   95.6   0.0  222   40-309    26-265 (337)
174 4PE6_B solute binding protein;  97.3 2.3E-07 1.7E-11   95.8   0.0  210   40-299    13-228 (341)
175 2X7X_A SENSOR PROTEIN (E.C.2.7  97.3 2.4E-07 1.7E-11   95.0   0.0  213   42-308     3-221 (325)
176 2X7X_B SENSOR PROTEIN (E.C.2.7  97.3 2.4E-07 1.7E-11   95.0   0.0  213   42-308     3-221 (325)
177 4RXM_A Possible sugar ABC supe  97.3 2.4E-07 1.8E-11   92.9   0.0  205   43-300     2-213 (292)
178 2HSG_A Glucose-resistance amyl  97.3 2.5E-07 1.8E-11   95.1   0.0  204   42-300    57-264 (332)
179 1ZHH_A Autoinducer 2-binding p  97.3 2.5E-07 1.8E-11   95.7   0.0  220   42-308    42-268 (344)
180 5ULB_A Putative sugar ABC tran  97.3 2.6E-07 1.9E-11   95.1   0.0  217   38-308    12-237 (337)
181 2FEP_A Catabolite control prot  97.3 2.7E-07 1.9E-11   92.6   0.0  206   40-300    11-220 (289)
182 2IKS_A DNA-binding transcripti  97.3 2.7E-07   2E-11   92.6   0.0  204   41-300    16-222 (293)
183 3D8U_A PurR transcriptional re  97.3 2.7E-07   2E-11   91.5   0.0  202   44-300     2-206 (275)
184 3D8U_B PurR transcriptional re  97.3 2.7E-07   2E-11   91.5   0.0  202   44-300     2-206 (275)
185 1JHZ_B PURINE NUCLEOTIDE SYNTH  97.3 2.7E-07   2E-11   92.4   0.0  206   41-300     3-212 (289)
186 2P9H_A Lactose operon represso  97.3 2.8E-07 2.1E-11   91.0   0.0  199   46-300     1-202 (269)
187 2PAF_B Lactose operon represso  97.3 2.8E-07 2.1E-11   91.0   0.0  199   46-300     1-202 (269)
188 3K4H_A putative transcriptiona  97.3 2.9E-07 2.1E-11   92.4   0.0  210   42-300     5-217 (292)
189 4RXT_A Sugar ABC transporter;   97.3   3E-07 2.1E-11   92.8   0.0  213   43-308     2-226 (299)
190 4ZJP_A solute binding protein;  97.3   3E-07 2.2E-11   92.3   0.0  206   38-299    17-229 (292)
191 2VK2_A ABC TRANSPORTER PERIPLA  97.3 3.2E-07 2.3E-11   92.9   0.0  205   45-300     2-216 (306)
192 1JFT_A PURINE NUCLEOTIDE SYNTH  97.3 3.2E-07 2.3E-11   94.5   0.0  206   41-300    54-263 (340)
193 3BRS_B Periplasmic binding pro  97.3 3.3E-07 2.4E-11   91.8   0.0  215   43-308     3-223 (289)
194 4RK4_A Transcriptional regulat  97.3 3.4E-07 2.4E-11   91.3   0.0  205   41-300     5-216 (283)
195 4RK5_A Transcriptional regulat  97.3 3.4E-07 2.4E-11   91.3   0.0  205   41-300     5-216 (283)
196 2QU7_B Putative transcriptiona  97.3 3.6E-07 2.6E-11   91.5   0.0  200   42-300     5-212 (288)
197 4IRX_B Sugar ABC transporter,   97.3 3.7E-07 2.7E-11   91.8   0.0  208   41-300     4-219 (296)
198 4RY9_A Periplasmic binding pro  97.2 3.9E-07 2.8E-11   91.9   0.0  205   42-300     4-223 (302)
199 3G1W_A Sugar ABC transporter;   97.2   4E-07 2.9E-11   92.1   0.0  213   43-308     2-220 (305)
200 3G1W_B Sugar ABC transporter;   97.2   4E-07 2.9E-11   92.1   0.0  213   43-308     2-220 (305)
201 5XSD_B Periplasmic binding pro  97.2 4.3E-07 3.1E-11   91.9   0.0  217   40-309    13-235 (306)
202 5DKV_A ABC transporter substra  97.2 4.3E-07 3.1E-11   92.8   0.0  219   42-308    24-253 (324)
203 1ZVV_B Glucose-resistance amyl  97.2 4.3E-07 3.2E-11   93.1   0.0  204   42-300    57-264 (332)
204 4KQ9_A Ribose ABC transporter,  97.2 4.6E-07 3.3E-11   91.2   0.0  205   42-299     4-214 (299)
205 5XSS_A Periplasmic binding pro  97.2 4.8E-07 3.5E-11   92.1   0.0  217   39-308    22-244 (316)
206 4YR7_A LuxP; PROTEIN-LIGAND CO  97.2 5.1E-07 3.7E-11   93.2   0.0  222   42-308    43-269 (345)
207 2IOY_A Periplasmic sugar-bindi  97.2 5.3E-07 3.8E-11   90.0   0.0  208   46-308     2-215 (283)
208 1TLF_C TRYPTIC CORE FRAGMENT O  97.2 5.3E-07 3.8E-11   91.0   0.0  200   45-300     2-204 (301)
209 3OQO_C Catabolite control prot  97.2 5.3E-07 3.8E-11   92.8   0.0  204   42-300    57-264 (339)
210 4RK6_A Glucose-resistance amyl  97.2 5.4E-07 3.9E-11   90.0   0.0  205   40-300     5-214 (287)
211 4RK7_B Glucose-resistance amyl  97.2 5.4E-07 3.9E-11   90.0   0.0  205   40-300     5-214 (287)
212 4RWE_A Sugar-binding transport  97.2   6E-07 4.3E-11   90.0   0.0  213   43-308     3-220 (292)
213 3GV0_A Transcriptional regulat  97.2 6.1E-07 4.4E-11   89.8   0.0  207   41-300     4-213 (288)
214 5HKO_A ABC transporter, carboh  97.2 6.3E-07 4.6E-11   92.7   0.0  214   40-309    28-248 (348)
215 4RXU_A Periplasmic sugar-bindi  97.2 6.5E-07 4.7E-11   93.4   0.0  153   39-241    24-182 (367)
216 4KMR_A Transcriptional regulat  97.1 6.7E-07 4.9E-11   88.9   0.0  201   44-300     2-208 (280)
217 3L6U_A ABC-TYPE SUGAR TRANSPOR  97.1 6.8E-07 4.9E-11   89.7   0.0  205   42-300     5-220 (293)
218 2DRI_A D-RIBOSE-BINDING PROTEI  97.1 6.8E-07 4.9E-11   88.2   0.0  207   46-308     2-214 (271)
219 3D02_A Putative LACI-type tran  97.1 6.9E-07   5E-11   90.1   0.0  214   43-308     2-222 (303)
220 4WZZ_A ABC TRANSPORTER SOLUTE   97.1 7.2E-07 5.2E-11   93.2   0.0  215   41-308    50-273 (371)
221 1JX6_A LUXP PROTEIN; PROTEIN-L  97.1 7.2E-07 5.2E-11   91.9   0.0  222   42-308    40-266 (342)
222 4WT7_A ABC TRANSPORTER SOLUTE   97.1 7.7E-07 5.5E-11   90.8   0.0  202   42-299    29-242 (321)
223 2RJO_A Twin-arginine transloca  97.1 8.7E-07 6.3E-11   90.9   0.0  217   43-307     3-229 (332)
224 4Y9T_A ABC TRANSPORTER SOLUTE   97.1 8.9E-07 6.5E-11   91.4   0.0  205   42-300    24-239 (346)
225 4RU1_A Monosaccharide ABC tran  97.1 9.1E-07 6.6E-11   89.3   0.0  206   39-299    14-223 (304)
226 4YV7_A ABC TRANSPORTER SOLUTE   97.1 9.4E-07 6.8E-11   90.2   0.0  215   39-309    34-255 (326)
227 2FN9_B ribose ABC transporter,  97.1   1E-06 7.3E-11   88.2   0.0  202   45-299     2-215 (290)
228 4XXH_B PROTEIN (TREHALOSE OPER  97.1   1E-06 7.4E-11   86.1   0.0  192   45-299     2-196 (255)
229 5IX8_B Putative sugar ABC tran  97.0 1.1E-06 8.2E-11   89.4   0.0  208   40-299    10-224 (321)
230 4WUT_A ABC TRANSPORTER SOLUTE   97.0 1.1E-06 8.2E-11   89.0   0.0  222   39-308    17-244 (313)
231 3HCW_A Maltose operon transcri  97.0 1.2E-06 8.5E-11   88.0   0.0  207   42-299     4-216 (295)
232 1JYE_A Lactose Operon Represso  97.0 1.2E-06   9E-11   90.4   0.0  203   42-300    58-263 (349)
233 2PE5_B Lactose operon represso  97.0 1.3E-06 9.2E-11   89.4   0.0  203   42-300    57-262 (330)
234 3C3K_B Alanine racemase (E.C.5  97.0 1.3E-06 9.5E-11   87.1   0.0  203   41-300     4-209 (285)
235 8ABP_A L-ARABINOSE-BINDING PRO  97.0 1.3E-06 9.6E-11   88.1   0.0  214   45-308     2-231 (306)
236 5ABP_A L-ARABINOSE-BINDING PRO  97.0 1.3E-06 9.7E-11   88.1   0.0  214   45-308     2-231 (306)
237 4KVF_A Rhamnose ABC transporte  97.0 1.5E-06 1.1E-10   89.5   0.0  217   39-307    33-257 (342)
238 3EDC_D Lactose operon represso  97.0 1.5E-06 1.1E-10   90.2   0.0  204   41-300    57-263 (360)
239 3KJX_D Transcriptional regulat  97.0 1.6E-06 1.1E-10   89.4   0.0  204   42-300    65-272 (344)
240 3KJX_C Transcriptional regulat  97.0 1.6E-06 1.1E-10   89.4   0.0  204   42-300    65-272 (344)
241 1GLG_A GALACTOSE/GLUCOSE-BINDI  97.0 1.6E-06 1.1E-10   87.7   0.0  217   45-309     2-236 (309)
242 2FVY_A D-galactose-binding per  97.0 1.6E-06 1.1E-10   87.7   0.0  217   45-309     2-236 (309)
243 3M9W_A D-xylose-binding peripl  97.0 1.6E-06 1.2E-10   87.9   0.0  211   45-308     2-221 (313)
244 3MA0_A D-xylose-binding peripl  97.0 1.6E-06 1.2E-10   87.9   0.0  211   45-308     2-221 (313)
245 3MA0_C D-xylose-binding peripl  97.0 1.6E-06 1.2E-10   87.9   0.0  211   45-308     2-221 (313)
246 5IBQ_A Probable ribose ABC tra  97.0 1.6E-06 1.2E-10   87.8   0.0  217   38-308    17-239 (310)
247 3K9C_B Transcriptional regulat  97.0 1.7E-06 1.2E-10   86.5   0.0  201   41-300     8-210 (289)
248 4RY8_B Periplasmic binding pro  97.0 1.7E-06 1.3E-10   88.4   0.0  215   40-308    10-230 (329)
249 4RY8_C Periplasmic binding pro  97.0 1.7E-06 1.3E-10   88.4   0.0  215   40-308    10-230 (329)
250 3ROT_A ABC sugar transporter,   96.9 1.9E-06 1.4E-10   86.6   0.0  205   44-299     2-212 (297)
251 3ROT_B ABC sugar transporter,   96.9 1.9E-06 1.4E-10   86.6   0.0  205   44-299     2-212 (297)
252 5BRA_A Putative periplasmic bi  96.9 1.9E-06 1.4E-10   89.0   0.0  220   37-308    36-262 (350)
253 2H3H_A Sugar ABC transporter,   96.9 1.9E-06 1.4E-10   87.3   0.0  209   45-308     1-215 (313)
254 2H3H_B Sugar ABC transporter,   96.9 1.9E-06 1.4E-10   87.3   0.0  209   45-308     1-215 (313)
255 3GBV_A Putative LacI-family tr  96.9 1.9E-06 1.4E-10   86.8   0.0  155   42-242     5-168 (304)
256 3HUU_A Transcription regulator  96.9 2.3E-06 1.7E-10   86.2   0.0  205   41-299    18-226 (305)
257 3HUU_C Transcription regulator  96.9 2.3E-06 1.7E-10   86.2   0.0  205   41-299    18-226 (305)
258 3KKE_C LacI family Transcripti  96.9 2.5E-06 1.8E-10   85.9   0.0  205   40-300    10-222 (303)
259 3KKE_B LacI family Transcripti  96.9 2.5E-06 1.8E-10   85.9   0.0  205   40-300    10-222 (303)
260 3BBL_A Regulatory protein of L  96.9 2.6E-06 1.9E-10   84.9   0.0  146  145-300    63-213 (287)
261 4PZ0_A sugar ABC transporter,   96.9 2.8E-06   2E-10   86.6   0.0  213   41-307     6-227 (324)
262 4YS6_A ABC TRANSPORTER SOLUTE   96.8 2.8E-06   2E-10   88.1   0.0  217   40-307    31-270 (360)
263 3L49_C ABC sugar (Ribose) tran  96.8 2.9E-06 2.1E-10   84.7   0.0  203   43-299     3-215 (291)
264 3JY6_A Transcriptional regulat  96.8   3E-06 2.1E-10   84.0   0.0  199   42-300     4-206 (276)
265 3JY6_D Transcriptional regulat  96.8   3E-06 2.1E-10   84.0   0.0  199   42-300     4-206 (276)
266 5HQJ_A Periplasmic binding pro  96.8   3E-06 2.2E-10   85.7   0.0  204   40-297    23-232 (311)
267 3EJW_A SmLsrB; Periplasmic bin  96.8 3.3E-06 2.4E-10   85.6   0.0  211   45-308     1-220 (315)
268 3QK7_C Transcriptional regulat  96.8 3.3E-06 2.4E-10   84.5   0.0  207   42-300     3-212 (294)
269 3E3M_D Transcriptional regulat  96.8 3.3E-06 2.4E-10   87.3   0.0  204   42-300    67-275 (355)
270 2WRZ_A L-ARABINOSE-BINDING PER  96.8 3.5E-06 2.5E-10   84.9   0.0  206   45-300     2-222 (306)
271 5BQ3_A Rhamnose ABC transporte  96.8 3.7E-06 2.7E-10   85.9   0.0  218   39-308    21-248 (332)
272 4RY0_A Probable ribose ABC tra  96.8 3.9E-06 2.8E-10   83.6   0.0  211   44-308     2-218 (289)
273 3TB6_A Arabinose metabolism tr  96.7 4.4E-06 3.2E-10   83.7   0.0  206   41-300    11-226 (298)
274 3GYB_A Transcriptional regulat  96.7 5.4E-06 3.9E-10   82.2   0.0  198   43-300     3-201 (280)
275 3GYB_B Transcriptional regulat  96.7 5.4E-06 3.9E-10   82.2   0.0  198   43-300     3-201 (280)
276 5UFH_A LacI-type transcription  96.7 5.9E-06 4.3E-10   85.0   0.0  202   43-300    63-278 (347)
277 3CTP_A Periplasmic binding pro  96.7   6E-06 4.3E-10   84.3   0.0  198   42-300    57-256 (330)
278 3G85_A Transcriptional regulat  96.7   6E-06 4.3E-10   82.3   0.0  204   41-300     7-213 (289)
279 3H5O_B Transcriptional regulat  96.7 6.1E-06 4.4E-10   84.6   0.0  203   42-300    59-264 (339)
280 5YSZ_A Transcriptional regulat  96.6 7.5E-06 5.4E-10   84.8   0.0  148  145-300   143-293 (360)
281 3MIZ_A Putative transcriptiona  96.6 8.6E-06 6.2E-10   81.7   0.0  206   41-300     9-222 (301)
282 1TJY_A sugar transport protein  96.6 9.4E-06 6.8E-10   82.2   0.0  210   44-308     2-221 (316)
283 4O5A_A LacI family transcripti  96.5 9.7E-06   7E-10   83.2   0.0  207   42-300    65-274 (345)
284 3UUG_B Multiple sugar-binding   96.5 1.2E-05 8.5E-10   82.0   0.0  206   44-300     2-229 (330)
285 3LKV_A uncharacterized CONSERV  96.5 1.3E-05 9.7E-10   80.1   0.0  215   41-308     4-226 (302)
286 4KQC_A Periplasmic binding pro  96.4 1.8E-05 1.3E-09   80.1   0.0  209   43-299     2-229 (319)
287 4WWH_A ABC TRANSPORTER SOLUTE   96.4 1.8E-05 1.3E-09   81.9   0.0  210   40-300    30-261 (362)
288 3CS3_A Sugar-binding transcrip  96.4 1.8E-05 1.3E-09   78.0   0.0  194   42-300     5-202 (277)
289 2H0A_A Transcriptional regulat  96.3 2.4E-05 1.7E-09   77.0   0.0  144  145-300    54-205 (276)
290 3E61_B Putative transcriptiona  96.3 2.5E-05 1.8E-09   77.0   0.0  197   41-300     4-202 (277)
291 3E61_A Putative transcriptiona  96.3 2.5E-05 1.8E-09   77.0   0.0  197   41-300     4-202 (277)
292 6HNI_A ABC-type transport syst  96.2 3.4E-05 2.4E-09   77.9   0.0  218   39-307    17-240 (319)
293 6HNJ_A ABC-type transport syst  96.2 3.4E-05 2.4E-09   77.9   0.0  218   39-307    17-240 (319)
294 3H75_A Periplasmic sugar-bindi  96.2 3.8E-05 2.7E-09   78.9   0.0  212   44-300     2-230 (350)
295 4RKQ_A Transcriptional regulat  96.1 4.6E-05 3.3E-09   75.8   0.0  199   40-300    10-216 (294)
296 4RKQ_B Transcriptional regulat  96.1 4.6E-05 3.3E-09   75.8   0.0  199   40-300    10-216 (294)
297 3LFT_A uncharacterized protein  96.0 5.4E-05 3.9E-09   75.1   0.0  202   45-298     2-209 (295)
298 3LFT_B uncharacterized protein  96.0 5.4E-05 3.9E-09   75.1   0.0  202   45-298     2-209 (295)
299 3HS3_B Ribose operon repressor  95.7 0.00012 8.5E-09   72.0   0.0  195   41-300     6-203 (277)
300 3JVD_A Transcriptional regulat  95.7 0.00012 8.9E-09   74.1   0.0  192   43-299    62-255 (333)
301 3JVD_B Transcriptional regulat  95.7 0.00012 8.9E-09   74.1   0.0  192   43-299    62-255 (333)
302 3S99_A Basic membrane lipoprot  95.7 0.00014 9.8E-09   74.7   0.0  216   27-298     9-229 (356)
303 6DSP_B Autoinducer 2-binding p  95.3 0.00028   2E-08   71.9   0.0  221   38-308    14-250 (347)
304 2FQW_A Membrane lipoprotein tm  95.3  0.0003 2.2E-08   70.6   0.0  146  145-300    61-213 (318)
305 2FQX_A Membrane lipoprotein tm  95.3  0.0003 2.2E-08   70.6   0.0  146  145-300    61-213 (318)
306 2FQY_A Membrane lipoprotein tm  95.3  0.0003 2.2E-08   70.6   0.0  146  145-300    61-213 (318)
307 3H5T_A Transcriptional regulat  95.0 0.00053 3.8E-08   70.4   0.0  146  145-300   127-293 (366)
308 6NDI_A Hypothetical Protein CD  94.9 0.00064 4.6E-08   68.6   0.0  144  145-299   119-269 (334)
309 6NDI_B Hypothetical Protein CD  94.9 0.00064 4.6E-08   68.6   0.0  144  145-299   119-269 (334)
310 4IIL_A Membrane lipoprotein Tp  94.8 0.00072 5.2E-08   68.7   0.0  212   40-299    27-252 (346)
311 6PI6_C Atrazine periplasmic bi  94.8 0.00074 5.3E-08   68.9   0.0  206   38-298    17-227 (355)
312 6PII_A Atrazine periplasmic bi  94.8 0.00074 5.3E-08   68.9   0.0  206   38-298    17-227 (355)
313 6RQG_A 46 kDa surface antigen;  94.7 0.00085 6.1E-08   69.0   0.0   92  145-241    76-195 (387)
314 6RUX_C Surface antigen P46; im  94.7 0.00085 6.1E-08   69.0   0.0   92  145-241    76-195 (387)
315 6S3T_T 46 kDa surface antigen,  94.7 0.00085 6.1E-08   69.0   0.0   92  145-241    76-195 (387)
316 4FE4_A Xylose operon regulator  94.6 0.00092 6.7E-08   69.2   0.0  148  145-300    55-208 (392)
317 4FE7_A Xylose operon regulator  94.4  0.0012 8.7E-08   68.9   0.0  205   38-300    18-228 (412)
318 2HQB_A Transcriptional activat  93.5  0.0031 2.3E-07   62.0   0.0  140  145-298    62-204 (296)
319 6SHU_A Basic membrane protein   93.3  0.0039 2.8E-07   63.5   0.0  205   41-298    43-252 (361)
320 4P98_A Basic membrane lipoprot  91.8    0.01 7.4E-07   58.8   0.0  133  145-283    74-210 (317)
321 4PEV_C solute binding protein;  90.2   0.022 1.6E-06   58.9   0.0  145  145-299   110-271 (422)
322 5ER3_A Sugar ABC transporter,   89.0   0.032 2.3E-06   55.7   0.0   91  145-242   237-332 (341)
323 3QI7_A Putative transcriptiona  87.1   0.055   4E-06   54.7   0.0  152  145-300    86-250 (371)
324 6U1N_R Muscarinic acetylcholin  78.8    0.23 1.6E-05   52.2   0.0   34  644-677    99-133 (509)
325 2Z73_A Rhodopsin; Visual pigme  72.8    0.44 3.2E-05   48.8   0.0   33  645-677   105-138 (448)
326 3AYN_A Rhodopsin; transmembran  72.8    0.44 3.2E-05   48.8   0.0   33  645-677   105-138 (448)
327 6P9X_R Guanine nucleotide-bind  69.6    0.58 4.2E-05   47.7   0.0   27  644-670   177-203 (427)
328 5X33_A LTB4 receptor,Lysozyme,  69.1    0.61 4.4E-05   49.0   0.0   18  644-661    87-104 (523)
329 5XSZ_A Lysophosphatidic acid r  67.4     0.7   5E-05   47.6   0.0   34  644-677    96-130 (477)
330 4PXZ_A P2Y purinoceptor 12, So  67.2    0.71 5.1E-05   47.3   0.0   34  644-677   102-136 (466)
331 6IGK_A Endothelin receptor typ  65.7     0.8 5.8E-05   47.5   0.0   34  644-677   108-142 (498)
332 3ODU_A C-X-C chemokine recepto  65.5     0.8 5.8E-05   47.6   0.0   34  644-677   115-149 (502)
333 5T04_A Neurotensin receptor ty  65.0    0.84 6.1E-05   47.6   0.0   16  645-660   107-122 (513)
334 3ODU_B C-X-C chemokine recepto  65.0    0.84 6.1E-05   47.4   0.0   35  644-678   115-150 (502)
335 3OE0_A C-X-C chemokine recepto  61.9       1 7.6E-05   46.5   0.0   34  644-677   115-149 (499)
336 5T1A_A C-C chemokine receptor   60.9     1.1 8.2E-05   46.5   0.0   34  644-677   119-153 (508)
337 6K41_R Guanine nucleotide-bind  60.4     1.2 8.4E-05   46.6   0.0   34  644-677   280-314 (512)
338 6K42_R Guanine nucleotide-bind  60.4     1.2 8.4E-05   46.6   0.0   34  644-677   280-314 (512)
339 5YC8_A Muscarinic acetylcholin  60.1     1.2 8.6E-05   44.6   0.0   18  644-661    94-111 (421)
340 6N4B_R Guanine nucleotide-bind  59.8     1.2 8.8E-05   46.2   0.0   18  587-604   138-155 (495)
341 3VW7_A Chimera of Proteinase-a  59.5     1.2   9E-05   45.6   0.0   34  644-677    89-123 (484)
342 6GPS_A C-C chemokine receptor   59.5     1.2   9E-05   44.6   0.0   23  644-666   108-130 (429)
343 6ME8_A Soluble cytochrome b562  59.0     1.3 9.3E-05   45.2   0.0   26  644-669   185-210 (460)
344 6ME6_A Soluble cytochrome b562  58.3     1.3 9.7E-05   45.1   0.0   34  644-677   185-219 (460)
345 4GRV_A Neurotensin receptor ty  58.1     1.4 9.8E-05   45.8   0.0   33  645-677   107-140 (510)
346 6WWZ_R Guanine nucleotide-bind  57.9     1.4  0.0001   46.3   0.0   33  644-676   259-292 (529)
347 5ZKC_A Muscarinic acetylcholin  57.5     1.4  0.0001   44.0   0.0   34  644-677    94-128 (421)
348 5IU7_A Adenosine receptor A2a,  57.2     1.4  0.0001   44.2   0.0   17  644-660    82-98  (433)
349 5NM4_A Lysozyme C (E.C.3.2.1.1  57.1     1.4  0.0001   44.2   0.0   17  644-660    82-98  (433)
350 5WIU_A D(4) dopamine receptor,  56.4     1.5 0.00011   43.9   0.0   22  644-665   108-129 (422)
351 5WIV_A D(4) dopamine receptor,  56.4     1.5 0.00011   43.9   0.0   22  644-665   108-129 (422)
352 5NDD_A Lysozyme,Proteinase-act  56.3     1.5 0.00011   46.9   0.0   34  644-677   273-307 (619)
353 4IB4_A Human 5-HT2B receptor_B  56.2     1.5 0.00011   43.9   0.0   34  644-677    99-133 (430)
354 6AK3_A Prostaglandin E2 recept  55.3     1.6 0.00012   43.5   0.0   19  644-662    88-106 (418)
355 6AK3_B Prostaglandin E2 recept  55.3     1.6 0.00012   43.5   0.0   19  644-662    88-106 (418)
356 6M9T_A Prostaglandin E2 recept  54.9     1.7 0.00012   45.6   0.0   17  645-661   139-155 (537)
357 5ZKP_A Platelet-activating fac  54.8     1.7 0.00012   44.2   0.0   34  644-677    88-122 (466)
358 5ZKQ_A Platelet-activating fac  54.6     1.7 0.00012   43.7   0.0   18  644-661    88-105 (438)
359 5W0P_C T4 lysozyme-human rhodo  54.4     1.7 0.00012   49.2   0.0   21  644-664   266-286 (906)
360 5W0P_B T4 lysozyme-human rhodo  54.0     1.8 0.00013   49.1   0.0   23  644-666   266-288 (906)
361 6OSA_R Neurotensin receptor ty  53.5     1.8 0.00013   43.5   0.0   16  645-660   158-173 (435)
362 4U14_A Muscarinic acetylcholin  52.9     1.9 0.00014   43.9   0.0   22  644-665    81-102 (460)
363 5TUD_A Chimera protein of 5-hy  52.5     1.9 0.00014   43.7   0.0   34  644-677   115-149 (457)
364 6C1R_B C5a anaphylatoxin chemo  52.2       2 0.00014   43.1   0.0   34  644-677   191-225 (422)
365 6OL9_A Muscarinic acetylcholin  52.1       2 0.00014   44.0   0.0   16  644-659    81-96  (480)
366 6LI0_A G-protein coupled recep  52.1       2 0.00014   43.8   0.0   34  644-677    95-129 (468)
367 4XES_A neurotensin receptor su  51.2     2.1 0.00015   44.6   0.0   33  645-677   107-140 (541)
368 6C1Q_B C5a anaphylatoxin chemo  51.0     2.1 0.00015   42.9   0.0   34  644-677   191-225 (422)
369 3V2Y_A Sphingosine 1-phosphate  50.5     2.2 0.00016   44.4   0.0   33  645-677   132-165 (520)
370 5UIW_A C-C chemokine receptor   50.3     2.2 0.00016   42.2   0.0   19  644-662    99-117 (411)
371 5OLZ_A Adenosine receptor A2a,  50.0     2.3 0.00016   42.6   0.0   16  645-660    84-99  (434)
372 6P9Y_R Guanine nucleotide-bind  49.7     2.3 0.00017   43.8   0.0   30  645-674   219-248 (483)
373 6MXT_A Fusion protein of Lysoz  49.3     2.4 0.00017   43.4   0.0   34  644-677   237-271 (472)
374 6KUX_A alpha2A adrenergic rece  48.9     2.4 0.00017   41.7   0.0   18  644-661    83-100 (395)
375 4U15_B M3-mT4L, Tiotropium; GP  48.4     2.5 0.00018   42.1   0.0   18  644-661    81-98  (418)
376 3EML_A Human Adenosine A2A rec  48.3     2.5 0.00018   43.3   0.0   15  644-658    88-102 (488)
377 6ORV_RP Guanine nucleotide-bin  48.2     2.5 0.00018   43.6   0.0   34  644-677   231-264 (491)
378 3PBL_A D(3) dopamine receptor;  47.8     2.6 0.00019   43.1   0.0   33  645-677   109-142 (481)
379 6CMO_R Soluble cytochrome b562  47.5     2.6 0.00019   42.9   0.0   34  644-677   246-280 (463)
380 6B3J_R Guanine nucleotide-bind  46.4     2.8  0.0002   43.2   0.0   34  644-677   231-264 (491)
381 4LDE_A Lysozyme, Beta-2 adrene  45.1       3 0.00022   42.4   0.0   33  644-676   251-284 (469)
382 5WF5_A Human A2a adenosine rec  44.9     3.1 0.00022   43.0   0.0   13  645-657   105-117 (504)
383 2R4R_A Beta-2 adrenergic recep  44.8     3.1 0.00022   40.1   0.0   17  644-660   102-118 (365)
384 5TGZ_A Cannabinoid receptor 1,  44.8     3.1 0.00022   42.0   0.0   20  585-604    27-46  (452)
385 3RZE_A Histamine H1 receptor/L  44.7     3.1 0.00022   42.0   0.0   18  644-661    77-94  (452)
386 6MEO_B Envelope glycoprotein g  44.7     3.1 0.00023   39.0   0.0   18  644-661    97-114 (313)
387 4ZUD_A Chimera protein of Solu  44.5     3.1 0.00023   41.1   0.0   22  644-665   192-213 (410)
388 4IAR_A Chimera protein of huma  44.4     3.2 0.00023   40.9   0.0   17  644-660    89-105 (401)
389 6D26_A Prostaglandin D2 recept  44.1     3.2 0.00023   42.0   0.0   33  645-677   102-135 (470)
390 6D27_A Prostaglandin D2 recept  44.1     3.2 0.00023   42.0   0.0   33  645-677   102-135 (470)
391 6A93_A 5-hydroxytryptamine rec  43.8     3.3 0.00024   40.2   0.0   18  644-661    78-95  (376)
392 6A94_A 5-hydroxytryptamine rec  43.8     3.3 0.00024   40.2   0.0   18  644-661    78-95  (376)
393 4IAQ_A 5-hydroxytryptamine rec  43.2     3.4 0.00025   40.6   0.0   18  644-661    89-106 (403)
394 6KPG_R Guanine nucleotide-bind  42.9     3.5 0.00025   41.9   0.0   18  586-603   166-183 (469)
395 4MQS_A Muscarinic acetylcholin  42.4     3.5 0.00026   39.4   0.0   18  644-661   109-126 (351)
396 4DJH_B Kappa-type opioid recep  42.3     3.6 0.00026   41.8   0.0   19  644-662    90-108 (480)
397 6OS0_A Type-1 angiotensin II r  42.3     3.6 0.00026   40.8   0.0   34  644-677   104-138 (425)
398 6OS1_A Type-1 angiotensin II r  42.3     3.6 0.00026   40.8   0.0   34  644-677   104-138 (425)
399 6OS2_A Type-1 angiotensin II r  42.3     3.6 0.00026   40.8   0.0   34  644-677   104-138 (425)
400 4YAY_A human Angiotensin Recep  41.9     3.7 0.00027   40.6   0.0   25  644-668   192-216 (414)
401 4N6H_A Soluble cytochrome b562  41.6     3.7 0.00027   40.6   0.0   34  644-677   193-227 (414)
402 6AKX_B Neuropeptide Y receptor  41.4     3.8 0.00027   39.8   0.0   22  644-665    99-120 (381)
403 6D9H_R Guanine nucleotide-bind  40.8     3.9 0.00028   40.0   0.0   16  645-660   132-147 (389)
404 6RZ4_A Cysteinyl leukotriene r  39.9     4.1  0.0003   40.3   0.0   35  644-678    95-130 (423)
405 6RZ5_B Cysteinyl leukotriene r  39.9     4.1  0.0003   40.3   0.0   35  644-678    95-130 (423)
406 5TVN_A 5-hydroxytryptamine rec  39.9     4.1  0.0003   39.9   0.0   34  644-677    84-118 (402)
407 5UZ7_R Guanine nucleotide-bind  39.5     4.3 0.00031   41.9   0.0   27  645-671   224-250 (501)
408 6I9K_A Kumopsin1; Rhodopsin, G  39.0     4.4 0.00032   39.3   0.0   17  645-661   120-136 (380)
409 4XNV_A P2Y purinoceptor 1, Rub  38.7     4.5 0.00032   40.0   0.0   33  645-677   120-153 (421)
410 4XNW_C P2Y purinoceptor 1, Rub  38.7     4.5 0.00032   40.0   0.0   33  645-677   120-153 (421)
411 5WB1_A Envelope protein US28,n  38.1     4.6 0.00033   40.6   0.0   34  644-677   108-142 (458)
412 6LI1_A G-protein coupled recep  38.1     4.6 0.00033   40.5   0.0   34  644-677    95-129 (449)
413 5UNG_B Soluble cytochrome b562  38.1     4.6 0.00033   39.7   0.0   33  644-676   189-222 (411)
414 5UNF_A Soluble cytochrome b562  37.9     4.7 0.00034   39.7   0.0   25  644-668   189-213 (411)
415 6J21_A Substance-P receptor (E  37.8     4.7 0.00034   40.1   0.0   34  644-677   100-134 (441)
416 5ZHP_A Muscarinic acetylcholin  37.7     4.7 0.00034   39.8   0.0   17  644-660    81-97  (418)
417 5NJ6_A Lysozyme,Proteinase-act  37.6     4.7 0.00034   40.1   0.0   34  644-677    91-125 (437)
418 5DSG_B Muscarinic acetylcholin  37.3     4.8 0.00035   39.8   0.0   17  644-660    82-98  (422)
419 4Z36_A Lysophosphatidic Acid R  37.2     4.9 0.00035   40.6   0.0   34  645-678   136-170 (459)
420 6PT0_R Cannabinoid receptor 2,  37.0     4.9 0.00036   38.7   0.0   12  645-656   103-114 (369)
421 6OIJ_R Guanine nucleotide-bind  36.5     5.1 0.00037   38.4   0.0   34  644-677   103-137 (363)
422 4Z35_A Lysophosphatidic Acid R  36.4     5.1 0.00037   40.5   0.0   14  645-658   136-149 (464)
423 6KR8_A beta 2 adrenergic recep  36.4     5.1 0.00037   37.8   0.0   34  644-677    79-113 (336)
424 6IIU_A Soluble cytochrome b562  36.2     5.2 0.00037   40.6   0.0   24  585-608   136-159 (484)
425 6IIV_A Soluble cytochrome b562  36.2     5.2 0.00037   40.6   0.0   24  585-608   136-159 (484)
426 6E3Y_R Calcitonin gene-related  36.1     5.2 0.00038   41.0   0.0   25  644-668   218-242 (490)
427 6UUN_R Guanine nucleotide-bind  36.1     5.2 0.00038   41.0   0.0   25  644-668   218-242 (490)
428 6M1I_A Ribonuclease 3 (E.C.3.1  35.5     5.4 0.00039   39.5   0.0   28  644-671   184-211 (406)
429 4XT1_A US28, CX3CL1, nanobody   35.4     5.4 0.00039   38.3   0.0   35  644-678   108-143 (362)
430 6LW5_A N-formyl peptide recept  35.2     5.5  0.0004   39.6   0.0   18  645-662   200-217 (427)
431 5VBL_B agonist peptide,Rubredo  34.9     5.6 0.00041   39.0   0.0   34  644-677   116-150 (407)
432 5V54_B OB-1 fused 5-HT1b recep  34.7     5.7 0.00041   38.7   0.0   34  644-677    82-116 (395)
433 5WB2_A Envelope protein US28,n  34.2     5.8 0.00042   39.8   0.0   34  644-677   107-141 (460)
434 6IBB_A Succinate receptor 1, N  33.2     6.2 0.00045   37.3   0.0   34  644-677    94-128 (342)
435 4GBR_A Beta-2 adrenergic recep  33.0     6.3 0.00046   36.4   0.0   17  644-660    74-90  (309)
436 6NBF_R Parathyroid hormone/par  32.2     6.7 0.00048   40.0   0.0   29  646-674   253-281 (478)
437 6NBH_R Parathyroid hormone/par  32.2     6.7 0.00048   40.0   0.0   29  646-674   253-281 (478)
438 6LML_R Guanine nucleotide-bind  31.9     6.8 0.00049   39.1   0.0   34  645-678   195-228 (422)
439 6WHC_R Guanine nucleotide-bind  31.8     6.8 0.00049   39.9   0.0   34  645-678   221-254 (477)
440 6LI2_A G-protein coupled recep  31.7     6.8  0.0005   37.6   0.0   34  644-677    95-129 (372)
441 4L6R_A Soluble cytochrome b562  31.2     7.1 0.00051   39.0   0.0   34  645-678   205-238 (425)
442 6KUW_A Alpha-2C adrenergic rec  31.1     7.1 0.00052   39.7   0.0   17  644-660    92-108 (496)
443 4WW3_A BOG; Animals, Decapodif  30.8     7.2 0.00052   36.9   0.0   17  644-660    96-112 (350)
444 6J20_A Substance-P receptor,En  30.6     7.3 0.00053   38.6   0.0   34  644-677   100-134 (441)
445 5YWY_A Prostaglandin E2 recept  30.6     7.3 0.00053   36.5   0.0   34  644-677    88-122 (332)
446 4JKV_A Soluble cytochrome b562  30.3     7.5 0.00054   39.5   0.0   34  644-677   230-263 (475)
447 4N4W_A Smoothened homolog; Hum  30.3     7.5 0.00054   39.5   0.0   34  644-677   230-263 (475)
448 6FJ3_A Parathyroid hormone/par  30.2     7.5 0.00054   41.0   0.0   33  646-678   214-246 (602)
449 5ZBH_A Neuropeptide Y receptor  29.8     7.7 0.00056   39.8   0.0   17  644-660   118-134 (527)
450 6NIY_R Adenosine receptor A1,S  29.6     7.9 0.00057   39.3   0.0   27  645-671   216-242 (474)
451 5XJM_A Type-2 angiotensin II r  29.0     8.1 0.00059   37.9   0.0   34  644-677    80-114 (422)
452 6VMS_R Guanine nucleotide-bind  28.9     8.2 0.00059   38.6   0.0   16  645-660   245-260 (450)
453 6PS2_A Fusion protein of Beta-  28.3     8.5 0.00062   39.4   0.0   34  644-677   126-160 (506)
454 6PB0_R Corticotropin-releasing  28.3     8.6 0.00062   37.3   0.0   28  644-671   161-188 (375)
455 3PDS_A Fusion protein Beta-2 a  28.1     8.7 0.00063   38.5   0.0   33  645-677    79-112 (458)
456 5UEN_B Adenosine receptor A1,S  27.5       9 0.00065   37.5   0.0   16  645-660    78-93  (416)
457 5ZBQ_A Neuropeptide Y Y1 recep  27.3     9.1 0.00066   39.2   0.0   20  644-663   108-127 (525)
458 6RNK_A Succinate receptor 1, N  27.3     9.1 0.00066   36.0   0.0   34  644-677    94-128 (342)
459 5UEN_A Adenosine receptor A1,S  27.1     9.2 0.00067   37.4   0.0   16  645-660    78-93  (416)
460 6PB1_P Corticotropin-releasing  26.9     9.4 0.00068   37.3   0.0   33  644-676   179-211 (387)
461 6OMM_R N-formyl peptide recept  26.6     9.6  0.0007   36.2   0.0   16  645-660   116-131 (363)
462 5N2S_A Adenosine receptor A2a,  26.3     9.8 0.00071   37.6   0.0   15  645-659   184-198 (436)
463 5LWE_A C-C chemokine receptor   25.1      11 0.00077   35.3   0.0   20  644-663    93-112 (331)
464 5ZTY_A G protein coupled recep  24.4      11 0.00081   38.3   0.0   20  585-604    37-56  (500)
465 2KSA_A Substance-P receptor, S  23.6      12 0.00086   35.5   0.0   16  645-660   102-117 (364)
466 5LWE_B C-C chemokine receptor   23.4      12 0.00087   34.9   0.0   18  644-661    93-110 (331)
467 5DHG_B Nociceptin receptor-Cyt  23.4      12 0.00087   36.7   0.0   34  644-677   193-227 (424)
468 5DHH_B GPCR-BRIL Chimera; Noci  23.4      12 0.00087   36.7   0.0   34  644-677   193-227 (424)
469 4DKL_A Mu-type opioid receptor  20.3      15  0.0011   36.5   0.0   17  644-660    85-101 (464)
470 5NX2_A Glucagon-like peptide 1  20.1      16  0.0011   36.1   0.0   33  645-677   204-236 (422)
471 6LN2_A Glucagon-like peptide 1  20.1      16  0.0011   36.9   0.0   35  644-678   199-233 (469)

No 1
>6N4X_A Metabotropic glutamate receptor 5; Cell Surface Receptor, MEMBRANE PROTEIN; HET: NAG; 4.0A {Homo sapiens}
Probab=100.00  E-value=2.5e-77  Score=724.04  Aligned_cols=801  Identities=44%  Similarity=0.813  Sum_probs=331.4  Template_Neff=10.300

Q NP_000836.2      35 EYAHSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDT  110 (908)
Q Consensus        35 ~~~~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~  110 (908)
                      ........+++++||+++|.++...    ....|+......+....+|+++|++++|+++++++|+++++.+.|+++++.
T Consensus        30 ~~~~~~~~~~~i~Ig~l~p~~~~~~~~~~~~~~C~~~~~~~g~~~~~a~~~Av~~iN~~~~~lp~~~l~~~i~Dt~~~~~  109 (877)
T 6N4X_A           30 ERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSA  109 (877)
T ss_dssp             CCCCCEEECCSEEEEEEECCBCCCCSGGGTTTCCCSBCCCCCCCHHHHHHHHHHHHHHCSSSSTTCCEEEEEEECTTSHH
T ss_pred             CceEEEEeCCCEEEEEEEecccCCCcccccccCccchhhccCHHHHHHHHHHHHHHhcCCCCCCCCeeeeEEecCCCCHH
Confidence            3444567889999999999987421    124566444445677899999999999998888889999999999998866


Q NP_000836.2     111 YALEQSLTFVQALIEK---DASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNT  187 (908)
Q Consensus       111 ~a~~~~~~~~~~l~~~---~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~  187 (908)
                      .+.+.+.+++.+....   ......|...++.+....+++++++|+.++..+..++.++...++|++++.++++.++++.
T Consensus       110 ~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~aviG~~~s~~~~~~a~~~~~~~ip~is~~~~s~~ls~~~  189 (877)
T 6N4X_A          110 VALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKT  189 (877)
T ss_dssp             HHHHHHHHHHHHHHHC--------------------CCCEEEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTT
T ss_pred             HHHHHHHHHHHhhcCCccccccceeccCCCCcccCCCCCeEEEECCCCcHHHHHHHHHHHHhCCCeEeecCCCcccCCcc
Confidence            5555544443321000   0000000000000001124788999998888878888899999999999988877776655


Q NP_000836.2     188 RYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIK  267 (908)
Q Consensus       188 ~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~  267 (908)
                      .+++++++.|++..+++++++++++++|++|++++++++++....+.+++.+++. ++++.....+..+....++...++
T Consensus       190 ~~p~~~r~~p~~~~~~~al~~~l~~~~w~~v~ii~~~~~~g~~~~~~~~~~~~~~-gi~i~~~~~~~~~~~~~~~~~~l~  268 (877)
T 6N4X_A          190 LFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKE-GICIAHSYKIYSNAGEQSFDKLLK  268 (877)
T ss_dssp             TSTTEEESSCCHHHHHHHHHHHHHHTTCCEEEEEECTTTTHHHHHHHHHHHHHHH-TCEEEEEEECCSSCCSSHHHHHHH
T ss_pred             ccCccccCCCCHHHHHHHHHHHHHHcCCcEEEEEEeCCcchHHHHHHHHHHHHHc-CcEEEEEEEecccCChHHHHHHHH
Confidence            6899999999999999999999999999999999987788888888888888775 466543322221112234556666


Q NP_000836.2     268 RLLE-TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFR  346 (908)
Q Consensus       268 ~l~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~  346 (908)
                      ++++ ..++++|++......+..+++++++.|+.+++.|++.+.|...............+.+.+.......+.|..++.
T Consensus       269 ~l~~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~f~~~~~  348 (877)
T 6N4X_A          269 KLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYL  348 (877)
T ss_dssp             HHHTTTTTCCEEEEECCHHHHHHHHHHHHHTTCSSCSEEEECGGGSSCHHHHTTCHHHHTTCEEEEECCCCCHHHHHHHT
T ss_pred             HHHhcCCCceEEEEECChhhHHHHHHHHHHhCCCCcEEEEEecccccCccccCCcccccccceeeeeeCCCCCcHHHHHH
Confidence            6653 126677777766667888999998888754456777665543221100011122333333322222333433332


Q NP_000836.2     347 SRTLANNRRNVWFAEFWEENFGCKLGSHGKR-NSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       347 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      ...+.....+.++.++|++.+++........ ..+...|+.......  ......++.++|||++++++|++++....+.
T Consensus       349 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~yDAv~~~a~al~~~~~~~~~  426 (877)
T 6N4X_A          349 KLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKT--HHVQDSKMGFVINAIYSMAYGLHNMQMSLCP  426 (877)
T ss_dssp             TCCTTTCCSSTTHHHHHHHHTTCCCTTSTTCCSSCCSCCCTTCCTTT--TCCCCTTHHHHHHHHHHHHHHHHHHHHHHSS
T ss_pred             hcCcccCCCChHHHHHHHHHcCCcCCCCCccccCCccccCCcceecc--cccccchHHHHHHHHHHHHHHHHHHHhccCC
Confidence            2211112234566777776655432110000 001112322211100  0112346778999999999999998764332


Q NP_000836.2     426 GYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTP-VTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVEDM  502 (908)
Q Consensus       426 ~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~-v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~~i  502 (908)
                      .....|......++..+.+.+++.+|+|.+| + ++||++|++...+.+.+++..+ +...++.||.|+... .++ ..+
T Consensus       427 ~~~~~c~~~~~~~~~~l~~~l~~~~f~G~tG-~~v~Fd~~G~~~~~~~I~~~~~~~~~~~~~~~Vg~~~~~~l~~~-~~~  504 (877)
T 6N4X_A          427 GYAGLCDAMKPIDGRKLLESLMKTNFTGVSG-DTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMD-DDE  504 (877)
T ss_dssp             SCSSCCSSSSSCCHHHHHHHHHHCEEECTTS-CEEECCTTSCCCCEEEEEEEEECSSSCEEEEEEEEEETTEEEEC-HHH
T ss_pred             CCCCCccccCCCCHHHHHHHHhcCeeecCCC-CEEEeCCCCCCCceeEEEEEEEeCCCeEEEEEEEEEeCCceEec-ccc
Confidence            2112232212234556778888889999988 6 9999999998889999987532 123578999998652 121 246


Q NP_000836.2     503 QWAHREHTHPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHS  581 (908)
Q Consensus       503 ~w~~~~~~~p~s~Cs~~c~~G~~k~~~~~-~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s~  581 (908)
                      .|.+ +...|.+.|+++|++|+++...++ +.|||.|.+|+.++++++..+|..||.+.||+++++.|...+..+..++.
T Consensus       505 ~w~~-~~~~p~s~c~~~C~~G~~~~~~~~~~~cc~~c~~C~~~~~~~~~~~c~~c~~~~~~~~~~~~c~~~~~~~~~~~~  583 (877)
T 6N4X_A          505 VWSK-KSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGD  583 (877)
T ss_dssp             HSSS-SSSSCCCCSSCCCCSSSCCCCCCSSCSSCCCCCCCCSSSCCCSSSCC----------------------------
T ss_pred             cccc-CCCcceeecCCCCCCCeeEeeeCCcceeceeEecCCCCeEeCCCcccccCCCCeeeCCCCCCCeeccceeccCCC
Confidence            7865 346689999999999998877666 68999999999999998889999999999999999999887788888999


Q NP_000836.2     582 PWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       582 ~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~~~~C~~~~~~~~~gf~l  661 (908)
                      ++.+++.++++++++++++++++++++|+++.+|++++.|+.++|+|++++|++++++++.|+...|.+|.|++++||++
T Consensus       584 ~~~i~~~~~~~~~i~~~~~~~~~~~~~r~~~~ik~~~~~~~~~~l~g~~l~~~~~~~~~~~~~~~~C~~~~~~~~l~f~l  663 (877)
T 6N4X_A          584 PEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAM  663 (877)
T ss_dssp             --------------------------------------------------------------------------------
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHccCCchhhcCCHHHHHHHHHHHHHHHHHHHHHccCcchhhHHHHHhHHHHHHHH
Confidence            99999999999999999999999999999999999999999999999999999999999999999999999999999999


Q NP_000836.2     662 SYAALLTKTNRIHRIFEQGKKSV--TAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGV  739 (908)
Q Consensus       662 ~~~~l~~K~~ri~~if~~~~~~~--~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~~~~~~~~~~  739 (908)
                      +||+|++|+||++++|.+++.++  ++.++++++.+++++++++++++++++.|+.++|+........       .....
T Consensus       664 ~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~-------~~~~~  736 (877)
T 6N4X_A          664 SYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPS-------IREVY  736 (877)
T ss_dssp             --------------------------------------------------------------------------------
T ss_pred             HHHHHHHHHHHHHHHHhcCCCCCCCCCCccCCHHHHHHHHHHHHHHHHHHHHHHHhcCCCCcccCCCc-------CceEE
Confidence            99999999999999998765421  1123567777888888899999999999999999876543211       12345


Q NP_000836.2     740 LKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLT  819 (908)
Q Consensus       740 ~~C~~~~~~~~~~~~~~~~ll~~~~~la~~~R~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  819 (908)
                      ..|.+.+.+++++++|+++|++++++|||++|++|++|||+|+|++++|+++++|++++++++.....       +.+.+
T Consensus       737 ~~C~~~~~~~~~~~~y~~~ll~~~~~la~~~R~~~~~~ne~~~i~~~~~~~~~~~~~~~~~~~~~~~~-------~~~~~  809 (877)
T 6N4X_A          737 LICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYK-------IITMC  809 (877)
T ss_dssp             --------------------------------------------------------------------------------
T ss_pred             EEccCCCHHhHHHHHHHHHHHHHHHHHHHHhcCCCccccHHHHHHHHHHHHHHHHHHHHHHHHcCCch-------HHHHH
Confidence            78998766677899999999999999999999999999999999999999999999999998654322       23666


Q NP_000836.2     820 VSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRS  855 (908)
Q Consensus       820 ~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~~  855 (908)
                      ++++++++++|+++|+||+|.++++|+++.+.+.+.
T Consensus       810 ~~~~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~~  845 (877)
T 6N4X_A          810 FSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTT  845 (877)
T ss_dssp             ------------------------------------
T ss_pred             HHHHHHHHHHHHHHHhhhhhHHHhCcccchhhhhee
Confidence            788899999999999999999999999988765333


No 2
>6N52_B Metabotropic glutamate receptor 5; Cell Surface Receptor, MEMBRANE PROTEIN; HET: NAG; 4.0A {Homo sapiens}
Probab=100.00  E-value=1.2e-76  Score=718.13  Aligned_cols=803  Identities=44%  Similarity=0.810  Sum_probs=569.0  Template_Neff=10.400

Q NP_000836.2      34 QEYAHSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD  109 (908)
Q Consensus        34 ~~~~~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~  109 (908)
                      ++.......+++++||+++|.++...    ....|+......+.....|+++|++++|+++++++|+++++.+.|+++++
T Consensus        29 ~~~~~~~~~~~~i~Ig~l~p~~~~~~~~~~~~~~C~~~~~~~g~~~~~a~~~Av~~iN~~~~~l~~~~l~~~i~Dt~~~~  108 (871)
T 6N52_B           29 SERRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHS  108 (871)
T ss_dssp             ---CCCEEECCSEEEEEEECCBCCCCGGGTTTTCCCSBCCCCCCHHHHHHHHHHHHHHSCTTSSTTCCEEEEEEECTTSH
T ss_pred             CCceEEEEeCCCEEEEEEEeeccCCCcccccccccccccccccHHHHHHHHHHHHHHhcCCCCCCCCeeccEEecCCCCH
Confidence            34445578899999999999987521    13467654444567788999999999999888888999999999999886


Q NP_000836.2     110 TYALEQSLTFVQALIEK---DASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN  186 (908)
Q Consensus       110 ~~a~~~~~~~~~~l~~~---~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~  186 (908)
                      ..+.+.+.+++.+....   ......|...++.+....+++++++|+.++..+.+++.++...++|++++.++++.++++
T Consensus       109 ~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~aviG~~~s~~~~~~a~~~~~~~ip~is~~~~s~~l~~~  188 (871)
T 6N52_B          109 AVALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDK  188 (871)
T ss_dssp             HHHHHHHHHHHHHHHHHHHC-------------CCCCCCCEEEEECCSCHHHHHHHHHHHGGGTCCEEESSCCCGGGGCT
T ss_pred             HHHHHHHHHHHHhccCCCcccccceeccCCCcccccCCCCeEEEECCCCcHHHHHHHHHHHHhCCCEEeeccCCcccCCc
Confidence            65555544443321000   000000000000000112478899999888877788889999999999998877777665


Q NP_000836.2     187 TRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKII  266 (908)
Q Consensus       187 ~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~  266 (908)
                      ..+++++++.|++..+++++++++++++|+++++++++++++....+.+++.+++. ++++.....+..+.+..++...+
T Consensus       189 ~~~p~~~r~~p~~~~~~~al~~~l~~~~w~~v~ii~~~~~~g~~~~~~~~~~~~~~-gi~i~~~~~~~~~~~~~~~~~~~  267 (871)
T 6N52_B          189 TLFKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKE-GICIAHSYKIYSNAGEQSFDKLL  267 (871)
T ss_dssp             TTCTTEEESSCCSHHHHHHHHHHHHHHTCCEEEEEEESSHHHHHHHHHHHHHHTTT-TCEECCCCEECTTCCHHHHHHHH
T ss_pred             cccCcccCCCCCHHHHHHHHHHHHHHcCCcEEEEEEeCCcchHHHHHHHHHHHHHc-CcEEEEEEEEccCCChHHHHHHH
Confidence            56899999999999999999999999999999999987778888888888888775 46654332222111223455666


Q NP_000836.2     267 KRLLE-TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       267 ~~l~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      +++++ ..+.+++++......+..+++++++.|+.+++.|++.+.|...............+.+.+.......+.|..++
T Consensus       268 ~~l~~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~f~~~~  347 (871)
T 6N52_B          268 KKLTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYY  347 (871)
T ss_dssp             HHHHTTTTTCCEEEEESCHHHHHHHHHHHHHHTCTTTCEEEECGGGSSCTTTTTTCTTTSTTCEEEEECCCCCHHHHHHH
T ss_pred             HHHHhcCCCceEEEEECChhhHHHHHHHHHHhCCCCcEEEEEecccccCccccCCchhhcccceeeeecCCCCCcHHHHH
Confidence            66652 12667777766666778899999888876445677766554322110001112233333332222233333333


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKR-NSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC  424 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~  424 (908)
                      ....+...+.+.++.++|++.+++........ ..+...|+..+....  ......++.++|||++++++|++++....+
T Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~yDAv~~~a~al~~~~~~~~  425 (871)
T 6N52_B          348 LKLRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKT--HHVQDSKMGFVINAIYSMAYGLHNMQMSLC  425 (871)
T ss_dssp             HTCCTTTCCSSTTHHHHHHHHSCEECTTSTTCCTTCCEECCTTCCSCT--TCCCCTTHHHHHHHHHHHHHHHHHHHHHHS
T ss_pred             HhcCcccCCCChHHHHHHHHHcCCCCCCCCcccccCcccCCCcccccc--ccccchhHHHHHHHHHHHHHHHHHHHhhcC
Confidence            22211122334566777776655432110000 001122332221110  012234677899999999999999876443


Q NP_000836.2     425 PGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTP-VTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVED  501 (908)
Q Consensus       425 ~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~-v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~~  501 (908)
                      ......|......++..+.+.+++.+|.|.+| + ++||++|++...+.+.+++..+ +...++.||.|+... .++ ..
T Consensus       426 ~~~~~~c~~~~~~~~~~l~~~l~~~~f~G~tG-~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~~vg~~~~~~l~~~-~~  503 (871)
T 6N52_B          426 PGYAGLCDAMKPIDGRKLLESLMKTNFTGVSG-DTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMD-DD  503 (871)
T ss_dssp             TTCSSCCGGGSSCCSHHHHHHHHTCEEECTTC-CEEECCTTCBCCCEEEEEEEECCSSSCCEEEEEEEEETTEEEEC-TT
T ss_pred             CCCCCCCcccCCCCHHHHHHHHhcCceecCCC-CEEEeCCCCCCCcceEEEEEEEeCCCeEEEEEEEEEeCCceEec-cc
Confidence            22112232222234556778888889999988 6 9999999998889999887532 123578999998652 122 24


Q NP_000836.2     502 MQWAHREHTHPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWH  580 (908)
Q Consensus       502 i~w~~~~~~~p~s~Cs~~c~~G~~k~~~~~-~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s  580 (908)
                      +.|.+ +...|.+.|+.+|++|+++...++ +.|||.|.+|+.++++++..+|..||.+.||+++++.|...+..+..++
T Consensus       504 ~~w~~-~~~~p~s~cs~~C~~G~~~~~~~~~~~cc~~c~~C~~~~~~~~~~~c~~c~~~~~~~~~~~~c~~~~~~~~~~~  582 (871)
T 6N52_B          504 EVWSK-KSNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWG  582 (871)
T ss_dssp             TSSSS-SCCSCCCCSSCCCCTTTEECCBCSSCSSCBCCEECCTTEEECSSSCEEECCTTEECCTTSSSCEECCCCCCCSS
T ss_pred             hhccc-CCCCceeeecCCCCCCeeEeccCCCCeeccCcccCCCCeEeCCCcccccCCCCeecCCCCCCceecceeeccCC
Confidence            67865 346689999999999999887767 6899999999999999988999999999999999999988777888889


Q NP_000836.2     581 SPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC  660 (908)
Q Consensus       581 ~~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~~~~C~~~~~~~~~gf~  660 (908)
                      .++.+++.++++++++++++++++++++|+++++|++++.+++++|+|++++|++++++++.|+...|.+|.|++++||+
T Consensus       583 ~~~~i~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~~~~~~~~~~l~g~~~~~~~~~~~~~~~~~~~C~~~~~~~~~gf~  662 (871)
T 6N52_B          583 DPEPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPA  662 (871)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHTTTTTTTTTCHHHHSSCTTHHHHHHHHHHHHHHHHHHHSSCCCTTHHHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHHHHHHHHHHHHHccCCCcccCCCHHHHHHHHHHHHHHHHHHHHHccCcchhHHHHHHhHHHHHHH
Confidence            99999999999999999999999999999999999999999999999999999999999999999999999999999999


Q NP_000836.2     661 FSYAALLTKTNRIHRIFEQGKKSV--TAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARG  738 (908)
Q Consensus       661 l~~~~l~~K~~ri~~if~~~~~~~--~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~~~~~~~~~  738 (908)
                      ++||+|++|+||++++|++.+.++  +..++++.+.+++++++++++++++++.|+.++|+........       ....
T Consensus       663 l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~i~~~~~~~~p~~~~~~~~~-------~~~~  735 (871)
T 6N52_B          663 MSYSALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPS-------IREV  735 (871)
T ss_dssp             HHHHHHHHHHHTCC--------------------CCHHHHHHHHHHHHHHHHHHHHHHSCCCEECCCSS-------SSCC
T ss_pred             HHHHHHHHHHHHHHHHHHcCCCCCCCCCCccCCHHHHHHHHHHHHHHHHHHHHHHHhcCCCCcccCCCC-------CceE
Confidence            999999999999999998765421  1123566777888888899999999999999999876533211       1234


Q NP_000836.2     739 VLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTL  818 (908)
Q Consensus       739 ~~~C~~~~~~~~~~~~~~~~ll~~~~~la~~~R~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  818 (908)
                      ...|.+.+.+++++++|.++|++++++|||++|++|++|||+|+|++++|+++++|++++++++.....       +.+.
T Consensus       736 ~~~C~~~~~~~~~~~~~~~~ll~~~~~la~~~R~~~~~~nE~k~i~~~~~~~~~~~~~~~~~~~~~~~~-------~~~~  808 (871)
T 6N52_B          736 YLICNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYK-------IITM  808 (871)
T ss_dssp             CCEECCCHHHHHHHHHHHHHHHHHHHHHHHHSTTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSSCT-------THHH
T ss_pred             EEEccCCcHHhHHHHHHHHHHHHHHHHHHHHhcCCCccccHHHHHHHHHHHHHHHHHHHHHHHhCCCch-------HHHH
Confidence            678998766677899999999999999999999999999999999999999999999999998755322       2366


Q NP_000836.2     819 TVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSF  856 (908)
Q Consensus       819 ~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~~~  856 (908)
                      ++.++++++++|+++|+||+|.++++|+++.+++.+.+
T Consensus       809 ~~~~~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~~~  846 (871)
T 6N52_B          809 CFSVSLSATVALGCMFVPKVYIILAKPERNVRSAFTTS  846 (871)
T ss_dssp             HHHHHHHHHHHHHTTTTTTSCCCCCSGGGC--------
T ss_pred             HHHHHHHHHHHHHHHHhhhhhhhhhCcccchhhhheec
Confidence            67888999999999999999999999998887664443


No 3
>6N51_B Metabotropic glutamate receptor 5, Nanobody; Cell Surface Receptor, MEMBRANE PROTEIN; HET: NAG, QUS; 4.0A {Homo sapiens}
Probab=100.00  E-value=6.7e-76  Score=706.52  Aligned_cols=786  Identities=44%  Similarity=0.821  Sum_probs=571.7  Template_Neff=10.700

Q NP_000836.2      37 AHSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYA  112 (908)
Q Consensus        37 ~~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a  112 (908)
                      ......+++++||+++|.|+...    ....|+......+.+...|+++|++++|+++++++|+++++++.|+++++..+
T Consensus         4 ~~~~~~~~~i~Ig~l~p~~~~~~~~~~~~~~c~~~~~~~g~~~~~a~~~Av~~iN~~~~~l~~~~l~~~~~Dt~~~~~~a   83 (804)
T 6N51_B            4 RVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAVA   83 (804)
T ss_pred             cceeEecCCEEEEeEeeccCCCCCCCCCCCCcccccCcccHHHHHHHHHHHHHHHcCCCCCCCCeeeEEEEeCCCCHHHH
Confidence            34467788999999999987532    13467754445667789999999999999888888999999999998876555


Q NP_000836.2     113 LEQSLTFVQALIEK---DASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRY  189 (908)
Q Consensus       113 ~~~~~~~~~~l~~~---~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~  189 (908)
                      .+.+.+++.+....   ......+...++.+...++++++++|+.++..+..++.+++..++|++++.+.++.++++..+
T Consensus        84 ~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~aviG~~~s~~~~~~a~~~~~~~ip~is~~~~~~~l~~~~~~  163 (804)
T 6N51_B           84 LEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTLF  163 (804)
T ss_pred             HHHHHHHHccCCCCCcccCCceecCCCCccccccCCCceEEEcCCChHHHHHHHHHHHHhCCCccccccCCcccCCcccC
Confidence            44444443210000   000000000000000112578899999888877788889999999999998877776655568


Q NP_000836.2     190 DFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRL  269 (908)
Q Consensus       190 ~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l  269 (908)
                      ++++++.|++..++.++++++++++|+++++++++++++....+.+++.+++. ++++.....+..+.+..++.+.++++
T Consensus       164 ~~~~r~~ps~~~~~~al~~~l~~~~w~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~i~~~~~~~~~~~~~~~~~~~~~l  242 (804)
T 6N51_B          164 KYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKE-GICIAHSYKIYSNAGEQSFDKLLKKL  242 (804)
T ss_pred             CcccccCCCHHHHHHHHHHHHHHhCCcEEEEEEecChhhHHHHHHHHHHHHHc-CcEEEEEEEeCCCCCccchHHHHHHH
Confidence            99999999999999999999988999999999988788888888888888775 46654332222111223455666666


Q NP_000836.2     270 LE-TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSR  348 (908)
Q Consensus       270 ~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~  348 (908)
                      ++ ..+.+++++......+..+++++++.|+.+++.|++.+.|...............+.+.+.........|..++...
T Consensus       243 ~~~~~~~~vvv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~f~~~~~~~  322 (804)
T 6N51_B          243 TSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLKL  322 (804)
T ss_pred             HhcCCCcEEEEEECCHHHHHHHHHHHHHhCCCCCeEEEEeccccCCCCccccchhhhceEEEEeccCCCCCCHHHHHHhC
Confidence            53 12567777666666778899999988876445677665544321110001112223333322222222333332221


Q NP_000836.2     349 TLANNRRNVWFAEFWEENFGCKLGSHGKR-NSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGY  427 (908)
Q Consensus       349 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~  427 (908)
                      .+.....+.++.++|++.+++........ ..+...|+..+....  ......++.++|||++++++|++++..+.+...
T Consensus       323 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~yDAv~~~a~al~~~~~~~~~~~  400 (804)
T 6N51_B          323 RPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKT--HHVQDSKMGFVINAIYSMAYGLHNMQMSLCPGY  400 (804)
T ss_pred             CCCCCCCChHHHHHHHHHcCCCCCCCCCCCCcCCccCCCCccccc--CCCcchhHHHHHHHHHHHHHHHHHHHhccCCCC
Confidence            11112234566677766655432110000 001123332221110  012334677899999999999999876443221


Q NP_000836.2     428 IGLCPRMSTIDGKELLGYIRAVNFNGSAGTP-VTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVEDMQW  504 (908)
Q Consensus       428 ~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~-v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~~i~w  504 (908)
                      ...|......++..+.+.+++.+|.|.+| . +.||++|++...+.+.+++..+ +...++.||.|+... .++ ..+.|
T Consensus       401 ~~~c~~~~~~~~~~l~~~l~~~~f~G~tG-~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~~vg~~~~~~l~~~-~~~~w  478 (804)
T 6N51_B          401 AGLCDAMKPIDGRKLLESLMKTNFTGVSG-DTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMD-DDEVW  478 (804)
T ss_pred             CCCCcccCCCCHHHHHHHHhheeeecCCC-CEEEECCCCCcCCeeEEEEEEECCCCcEEEEEEEEEcCCceEEe-ceeec
Confidence            12222212234556778888889999988 6 9999999998889999988532 223578999998652 222 24678


Q NP_000836.2     505 AHREHTHPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPW  583 (908)
Q Consensus       505 ~~~~~~~p~s~Cs~~c~~G~~k~~~~~-~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s~~~  583 (908)
                      ..+ ...|.+.|+.+|++|+++...++ +.|||.|.+|+.++++++..+|..||.+++|+++++.|...+..+..+++++
T Consensus       479 ~~~-~~~p~s~cs~~C~~g~~~~~~~~~~~cc~~c~~C~~~~~~~~~~~c~~c~~~~~~~~~~t~c~~~~~~~~~~~~~~  557 (804)
T 6N51_B          479 SKK-SNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQYLRWGDPE  557 (804)
T ss_pred             CCC-CCCCCccccCCCCCCceecCCCCCCccceeeeeCCCCcccCCCcceecCCCCCcCCCCCCceeeccchhcCCCcHH
Confidence            652 46689999999999998877666 7899999999999999888999999999999999999988888888999999


Q NP_000836.2     584 AVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMCFSY  663 (908)
Q Consensus       584 ~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~~~~C~~~~~~~~~gf~l~~  663 (908)
                      .+++.++++++++++++++++++++|+++.+|++++.+++++|+|++++|++++++++.|+...|.+|.|++++||+++|
T Consensus       558 ~i~~~~~~~~~i~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~l~g~~~~~~~~~~~~~~~~~~~C~~~~~~~~~~~~l~~  637 (804)
T 6N51_B          558 PIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFCLIAKPKQIYCYLQRIGIGLSPAMSY  637 (804)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHCCCCcccccCCHHHHHHHHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHHHHH
Confidence            99999999999999999999999999999999999999999999999999999999999999999999999999999999


Q NP_000836.2     664 AALLTKTNRIHRIFEQGKKSV--TAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRTLDPEKARGVLK  741 (908)
Q Consensus       664 ~~l~~K~~ri~~if~~~~~~~--~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~~~~~~~~~~~~  741 (908)
                      |+|++|+||++++|++++.++  +..++++.+.+++++++++++|+++++.|+.++|+........       ....+..
T Consensus       638 ~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~-------~~~~~~~  710 (804)
T 6N51_B          638 SALVTKTNRIARILAGSKKKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPS-------IREVYLI  710 (804)
T ss_pred             HHHHHHHHHHHHHHhcCCCCCCCCccccCCHHHHHHHHHHHHHHHHHHHHHHHHhCCCCCCCCCCC-------CCcEEEE
Confidence            999999999999998765321  1123456677777888889999999999999999876543211       1234668


Q NP_000836.2     742 CDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVS  821 (908)
Q Consensus       742 C~~~~~~~~~~~~~~~~ll~~~~~la~~~R~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  821 (908)
                      |...+.+++++++|.++|++++++|||++|++|++|||+|+|++++|+++++|++++++++.....       +.+.+++
T Consensus       711 C~~~~~~~~~~~~~~~~ll~~~~~la~~~r~~~~~~~e~~~i~~~~~~~~~~~~~~~~~~~~~~~~-------~~~~~~~  783 (804)
T 6N51_B          711 CNTTNLGVVTPLGYNGLLILSCTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYK-------IITMCFS  783 (804)
T ss_pred             cCCCcHHHHHHHHHHHHHHHHHHHHHHHhCCCCccccHHHHHHHHHHHHHHHHHHHHHHHhCCCch-------HHHHHHH
Confidence            998766677899999999999999999999999999999999999999999999999998765322       2366788


Q NP_000836.2     822 MSLSASVSLGMLYMPKVYIII  842 (908)
Q Consensus       822 i~~~~~~~l~~~f~PK~~~i~  842 (908)
                      ++++++++|+++|+||+|.|+
T Consensus       784 ~~~~~~~~l~~~f~Pk~~~i~  804 (804)
T 6N51_B          784 VSLSATVALGCMFVPKVYIIL  804 (804)
T ss_pred             HHHHHHHHHHHHHHhhhhhcC
Confidence            899999999999999999874


No 4
>6W2Y_A Gamma-aminobutyric acid type B receptor; Inhibitor, Homodimer, GPCR, SIGNALING PROTEIN; HET: SGG, L9Q, NAG; 3.2A {Homo sapiens}
Probab=100.00  E-value=3.8e-66  Score=620.75  Aligned_cols=685  Identities=21%  Similarity=0.299  Sum_probs=472.4  Template_Neff=10.100

Q NP_000836.2      36 YAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQ  115 (908)
Q Consensus        36 ~~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~  115 (908)
                      .......+++++||+++|.++..           ..+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.
T Consensus        22 ~~~~~~~~~~i~IG~l~p~~~~~-----------~~g~~~~~a~~~Av~~iN~~~~il~g~~l~l~~~Dt~~~~~~a~~~   90 (829)
T 6W2Y_A           22 PPHPSSERRAVYIGALFPMSGGW-----------PGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKY   90 (829)
T ss_dssp             ------CCEEEEEEEEECSSSSC-----------CCSTTTHHHHHHHHHHHHHCTTTSTTEEEEEEEEECTTCHHHHHHH
T ss_pred             CCCCCCCCceEEEEEEEecCCCC-----------CCcchHHHHHHHHHHHHHhCCCCCCCcEEEEEEecCCCCHHHHHHH
Confidence            34455677899999999998642           1356778999999999999888888999999999998876544433


Q NP_000836.2     116 SLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRV  195 (908)
Q Consensus       116 ~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~  195 (908)
                      +.+++.                      .+++++++|+.++..+..++.+++.+++|+|+++++++.++++..+++++|+
T Consensus        91 ~~~l~~----------------------~~~v~~viG~~~s~~~~~va~~~~~~~ip~is~~a~s~~ls~~~~~p~~frt  148 (829)
T 6W2Y_A           91 LYELLY----------------------NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRT  148 (829)
T ss_dssp             HHHTTS----------------------SSSCEEEEEECSHHHHHHHHHTTTTTTCEEEESSCCCGGGGCTTTCTTEEES
T ss_pred             HHHHHh----------------------cCCcEEEEECCChHHHHHHHHHHHHcCCEEEecccCChhHhccccCCceEEc
Confidence            333322                      1478899999888888888899999999999999888887776678999999


Q NP_000836.2     196 VPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~  275 (908)
                      .|++..++.++++++++++|++|++++++++++....+.+++.+++. ++++.....+.     .+....++++++ .++
T Consensus       149 ~ps~~~~~~a~~~ll~~~~w~~vaii~~~~~~~~~~~~~~~~~~~~~-gi~v~~~~~~~-----~d~~~~~~~l~~-~~~  221 (829)
T 6W2Y_A          149 HPSATLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEA-GIEITFRQSFF-----SDPAVPVKNLKR-QDA  221 (829)
T ss_dssp             SCCSGGGHHHHHHHHHHHCCCEEEEEECCSTTHHHHHHHHHHHHHTT-TCEEEEEEECS-----SCCHHHHHHHHH-TTC
T ss_pred             CCChhhccHHHHHHHHHhCCeEEEEEEeCCcccchhHHHHHHHHHHc-CCEEEEEEccc-----CCchHHHHHHhh-CCC
Confidence            99999999999999999999999999988888888888888888775 47765443332     134455667763 578


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSD----SWGSKIAPV-----YQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~----~~~~~~~~~-----~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      ++|++......+..+++++++.|+.+ ++.|+..+    .|.......     .......+|.+.......         
T Consensus       222 riIv~~~~~~~~~~~l~~a~~~g~~~~~~vwi~~~~~~~~w~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~---------  292 (829)
T 6W2Y_A          222 RIIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVML---------  292 (829)
T ss_dssp             SEEEEECCHHHHHHHHHHHTTTTCCSTTCEEEEESCSCSSCTTSCCTTCCSCHHHHHTTTTTCEEEEECCS---------
T ss_pred             EEEEEeCCHHHHHHHHHHHHHccccCCCeEEEEeccccccchhccCCCCCCCHHHHHHHHcccEEEEEecc---------
Confidence            99988877777888999998888764 56777653    222110000     001112233322211000         


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      ... ......+.++.++++++..+ ....   +    .           ......++..+|||++++++|++++....+.
T Consensus       293 ~~~-~~~~~~~~~~~~f~~~~~~~-~~~~---~----~-----------~~~~~~~a~~~YDAv~~~a~Al~~~~~~~~~  352 (829)
T 6W2Y_A          293 NPA-NTRSISNMTSQEFVEKLTKR-LKRH---P----E-----------ETGGFQEAPLAYDAIWALALALNKTSGGGGR  352 (829)
T ss_dssp             CCS-CCCCTTSCCHHHHHHHHHTT-CSSC---T----T-----------TSTTSSSHHHHHHHHHHHHHHHHHHC-----
T ss_pred             CCC-CCCCcCCCCHHHHHHHHHHH-HhcC---C----c-----------cCCCCccccHHHHHHHHHHHHHHHHhhcCcc
Confidence            000 00000122233333322111 1000   0    0           0112345778999999999999998754321


Q NP_000836.2     426 GYIGLCPR----MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVED  501 (908)
Q Consensus       426 ~~~~~~~~----~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~  501 (908)
                      .  +.+..    .....++.+.++|++.+|.|.+| ++.||++|++...+.+.+++    ++.++.||.|+....    .
T Consensus       353 ~--~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~tG-~v~fd~~G~r~~~~~i~~~~----~~~~~~vg~~~~~~~----~  421 (829)
T 6W2Y_A          353 S--GVRLEDFNYNNQTITDQIYRAMNSSSFEGVSG-HVVFDASGSRMAWTLIEQLQ----GGSYKKIGYYDSTKD----D  421 (829)
T ss_dssp             -----CCTTCCTTCTTHHHHHHHHHHTCEEEETTE-EEEBCTTSCBCCEEEEEEES----SSSEEEEEEEETTTC----C
T ss_pred             C--CCCHHHcCCCChHHHHHHHHHHHcCcccccee-eEEeCCCCCccceEEEEEee----CCeEEEEEEEECCCC----C
Confidence            1  10100    01123446778888889999988 89999999998888888887    357899999986531    2


Q NP_000836.2     502 MQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHS  581 (908)
Q Consensus       502 i~w~~~~~~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s~  581 (908)
                      +.|...          ..|+.|.                               +|.|      ++.|   ...+..++.
T Consensus       422 l~~~~~----------~~w~~g~-------------------------------~p~d------~~~~---~~~~~~~s~  451 (829)
T 6W2Y_A          422 LSWSKT----------DKWIGGS-------------------------------PPAD------QTLV---IKTFRFLSQ  451 (829)
T ss_dssp             CBCCSC----------CCCSSSS-------------------------------CCCS------SCCE---EEEECCCCS
T ss_pred             ceecCC----------CccCCCC-------------------------------CCCC------Ccee---ceeecccCH
Confidence            344221          1222221                               2434      4444   334455667


Q NP_000836.2     582 PWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFL------MIAAP-DTIICSFRRVF  654 (908)
Q Consensus       582 ~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~------~~~~~-~~~~C~~~~~~  654 (908)
                      ++.+++.++++++++++++++++++++|+++.+|+++|.+++++|+|++++|+++++      ++..+ +...|.+|.|+
T Consensus       452 ~~~i~~~~~~~~gi~~~~~~~~~~~~~r~~~~ik~s~~~l~~~~l~G~~l~~~~~~~~~~~~~~i~~~~~~~~C~~~~~~  531 (829)
T 6W2Y_A          452 KLFISVSVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWL  531 (829)
T ss_dssp             SHHHHHHHHHHHHHHHHHHHHHHHHSCSSSHHHHHSCHHHHHHHHHHHHHHHHTTTTTTCSSSSCCTTTHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHcccChhhhCCCHHHHHHHHHHHHHHHHHHHHhcCCccCCCcccccHHHHHHHHH
Confidence            788888999999999999999999999999999999999999999999999999986      34444 68999999999


Q NP_000836.2     655 LGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRT----  730 (908)
Q Consensus       655 ~~~gf~l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~----  730 (908)
                      +++||+++||+|++|+||++++|++++.++.+++.++++.++.++++++++|++++++|++++|+..........+    
T Consensus       532 ~~~gf~l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~l~~~~~~l~~i~~iil~~w~~~~p~~~~~~~~~~~~~~~~  611 (829)
T 6W2Y_A          532 LGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKED  611 (829)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHTC---------------CCHHHHHHHHHHHHHHHHHHHHHHSCCCEEEEECCCCCC---
T ss_pred             HHHHHHHHHHHhhhhceEEEEEeecccccchhhccCCHHHHHHHHHHHHHHHHHHHHHHHHHCcccceeeecccCCCCcc
Confidence            9999999999999999999999997765322245678899999999999999999999999999986543211000    


Q NP_000836.2     731 LDPEKARGVLKCDISD--LSLICSLGYSILLMVTCTVYAIKTRGVP-ETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQS  807 (908)
Q Consensus       731 ~~~~~~~~~~~C~~~~--~~~~~~~~~~~~ll~~~~~la~~~R~~~-~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~  807 (908)
                      .+....+..+.|.+.+  .|++++++|+++|+++|++|||++|+++ ++|||+|+|++++|+++++|+++++++++....
T Consensus       612 ~~~~~~~~~~~C~~~~~~~~~~~~~~y~~lll~~~~~la~~tR~~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~  691 (829)
T 6W2Y_A          612 IDVSILPQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQ  691 (829)
T ss_dssp             -CCEEEEEEEEECCSSHHHHHHHHHHHHHHHHHHHHHHHHHTCC------CCCSTHHHHHHHHHHHHHHHHHHHHHGGGC
T ss_pred             CCceeeceEEeecCCCcHHHHHHHHHHHHHHHHHHHHHHHHhcCCCchhhccHHHHHHHHHHHHHHHHHHHHHHHHhcCc
Confidence            0000123367999864  7888999999999999999999999999 899999999999999999999999998766543


Q NP_000836.2     808 AEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRK  853 (908)
Q Consensus       808 ~~~~~~~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~  853 (908)
                      +   ...+.+.+++++++++++|+++|+||+|.++++++.+.+...
T Consensus       692 ~---~~~~~~~~~~i~~~~~~~l~~~f~PK~~~~~~~~~~~~~~~~  734 (829)
T 6W2Y_A          692 Q---DAAFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQD  734 (829)
T ss_dssp             T---TTHHHHHHHHHHHHHHHHHHHHTHHHHHHHC-----------
T ss_pred             h---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccchhhhh
Confidence            2   355678889999999999999999999999998887765543


No 5
>6W2X_B Gamma-aminobutyric acid type B receptor; Inhibitor, Heterodimer, GPCR, SIGNALING PROTEIN; HET: SGG, L9Q, NAG; 3.6A {Homo sapiens}
Probab=100.00  E-value=8.6e-65  Score=611.36  Aligned_cols=678  Identities=20%  Similarity=0.302  Sum_probs=482.9  Template_Neff=9.500

Q NP_000836.2      36 YAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQ  115 (908)
Q Consensus        36 ~~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~  115 (908)
                      ........++++||+++|.++....        ...+.....|+++|++++|+++ .++|+++++.+.|+++++..+.+.
T Consensus        13 ~~~~~~~~~~i~IG~l~p~s~~~~~--------~~~g~~~~~a~~~Av~~IN~~~-~l~~~~l~l~~~Dt~~~~~~a~~~   83 (908)
T 6W2X_B           13 APRPPPSSPPLSIMGLMPLTKEVAK--------GSIGRGVLPAVELAIEQIRNES-LLRPYFLDLRLYDTECDNAKGLKA   83 (908)
T ss_dssp             -------CCEEEEEEECCCCSSSTT--------THHHHSSHHHHHHHHHHHHHHT-CSSSCEEEEEEECCTTCHHHHHHH
T ss_pred             CCCCCCCCCCEEEEEEEeCCccccC--------CcccccHHHHHHHHHHHHHhcC-CCCCeEEEEEEecCCCChHHHHHH
Confidence            3445567889999999999874310        0246678899999999999875 466899999999998876544443


Q NP_000836.2     116 SLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRV  195 (908)
Q Consensus       116 ~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~  195 (908)
                      +.+++.    .                 .+++++++|+.++..+.+++.+++.+++|+|+++++++.++++..+++++|+
T Consensus        84 ~~~ll~----~-----------------~~~v~aviG~~~S~~~~~va~~~~~~~ip~Is~~ats~~Ls~~~~yp~ffrt  142 (908)
T 6W2X_B           84 FYDAIK----Y-----------------GPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRT  142 (908)
T ss_dssp             HHHHHH----T-----------------SCCCCCEEECCSHHHHHHHTTSCTTTTCCEEESSCCCSGGGCTTTCSSEEES
T ss_pred             HHHHHH----h-----------------CCCeEEEEecCCHHHHHHHHHHhcccCCEEEEcccCChhHcCcccCCceeec
Confidence            333332    1                 1368899999988888888999999999999999988888776678999999


Q NP_000836.2     196 VPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~  275 (908)
                      .|++..+++++++++++++|++|++++++++++....+.+++.+++. ++++.....+.     .+....++++++ .++
T Consensus       143 ~ps~~~~~~al~~ll~~~~W~~Vaii~~d~~~g~~~~~~~~~~~~~~-gi~i~~~~~~~-----~d~~~~l~~lk~-~~a  215 (908)
T 6W2X_B          143 VPSDNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGE-DIEISDTESFS-----NDPCTSVKKLKG-NDV  215 (908)
T ss_dssp             SCCTTSSHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHTTTS-SCEEEEEEEES-----SCCHHHHHHHHH-HTC
T ss_pred             CCCHHhhcHHHHHHHHHcCCcEEEEEEeccHHHHHHHHHHHHHHhcC-CCEEeeEeeec-----CChhHHHHHHhc-CCc
Confidence            99999999999999999999999999988888888888888877775 46765443332     234556677763 578


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVY-------------QQEEIAEGAVTILPKRASIDGF  341 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~-------------~~~~~~~g~~~~~~~~~~~~~~  341 (908)
                      ++|++......+..+++++.+.|+.+ ++.|+..+ |........             ......+|.+.+.........+
T Consensus       216 riIv~~~~~~~~~~~l~~a~~~g~~~~~~vwI~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~i~~~~~~~~~~~~  294 (908)
T 6W2X_B          216 RIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPG-WYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQI  294 (908)
T ss_dssp             CEEECCCCHHHHHHHHHHHHHHTCCSTTCEEECCC-CCCTTTTC------------CHHHHHHHSSEEEEEECSSCCCCC
T ss_pred             EEEEEeCCHHHHHHHHHHHHHcCCCCCCeEEEeec-CCCcchHHhccccccCCcchHHHHHHHHCCceEEEecCCCcCcc
Confidence            99888877777888999998888764 57788764 322110000             0111223333222111000000


Q NP_000836.2     342 DRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHK  421 (908)
Q Consensus       342 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~  421 (908)
                      ..+          ......++. +.+.+...                      ...+..++.++|||++++|+|++++..
T Consensus       295 ~~~----------~~~~~~~~~-~~~~~~~~----------------------~~~~~~~~~~aYDAv~~lA~Al~~~~~  341 (908)
T 6W2X_B          295 KTI----------SGKTPQQYE-REYNNKRS----------------------GVGPSKFHGYAYDGIWVIAKTLQRAME  341 (908)
T ss_dssp             CCT----------TSCCHHHHH-HHHHHHCS----------------------SSCCCTTHHHHHHHHHHHHHHHHHHHH
T ss_pred             ccc----------CCCCHHHHH-HHHHhhcC----------------------CCCCccchHHHHHHHHHHHHHHHHHHH
Confidence            000          000011111 11211100                      012345678899999999999999876


Q NP_000836.2     422 DLCPGY----IGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLH-  496 (908)
Q Consensus       422 ~~~~~~----~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~-  496 (908)
                      ..+...    ...+.......+..+.++|++.+|.|.+| ++.|| +|++...+.+.+++    ++.++.||.|+.... 
T Consensus       342 ~~~~~~~~~~l~~~~~~~~~~g~~l~~~l~~~~F~G~tG-~v~Fd-~Gdr~~~~~I~~~~----~~~~~~VG~~~~~~~~  415 (908)
T 6W2X_B          342 TLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTG-QVVFR-NGERMGTIKFTQFQ----DSREVKVGEYNAVADT  415 (908)
T ss_dssp             HHHTC-----CCSCCTTCHHHHHHHHHHHTSCCCEETTE-ECCBS-SSSBCCEEEEEEEC----SSSEEEEEEEETTTTE
T ss_pred             HHHhcCCCCcHHhcCCCChHHHHHHHHHHHcCceecCce-eEEEe-CCceeceEEEEEEe----CCeEEEEEEEECCCCe
Confidence            432110    00010111224556778888889999988 89999 89998889999988    257899999986421 


Q NP_000836.2     497 --LKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPI  574 (908)
Q Consensus       497 --~~~~~i~w~~~~~~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~  574 (908)
                        +....+.|.+                |.                               +|.+      ++.|   ..
T Consensus       416 l~~~~~~i~w~g----------------~~-------------------------------~P~d------~~~~---~~  439 (908)
T 6W2X_B          416 LEIINDTIRFQG----------------SE-------------------------------PPKD------KTII---LE  439 (908)
T ss_dssp             EECCTTTCCCSS----------------SS-------------------------------CCCS------SCCE---EC
T ss_pred             EEEEccccccCC----------------CC-------------------------------CCCC------ccch---hh
Confidence              1111223321                10                               2333      3333   23


Q NP_000836.2     575 IKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPD-------TII  647 (908)
Q Consensus       575 ~~~~~s~~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~-------~~~  647 (908)
                      ....++.++.+++.++++++++++++++++++++|+++.+|++++.+++++|+|++++|++++++++.++       ...
T Consensus       440 ~~~~~~~~~~~~~~~~~~~gi~~~~~~l~~~~~~r~~~~ik~s~~~l~~~il~G~~l~~~~~~~~~~~~~~~~~~~~~~~  519 (908)
T 6W2X_B          440 QLRKISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETL  519 (908)
T ss_dssp             CCCCCCSSSHHHHHHHHHHHHHHHHHHHHHHHHTTTSHHHHHSCSSHHHHHHHHHHHHHHHHHHHHCCSSSSCHHHHHHH
T ss_pred             HHhcCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcchhHHhCCHHHHHHHHHHHHHHHHHHHHHhcCCCCCChhHHHHH
Confidence            3336677788888899999999999888899999999999999999999999999999999999888776       789


Q NP_000836.2     648 CSFRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGE  727 (908)
Q Consensus       648 C~~~~~~~~~gf~l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~  727 (908)
                      |.+|.|++++||+++||+|++|+||++++|++++.+   ++.++++.++.+++++++++++++++|++++|+........
T Consensus       520 C~~~~w~~~lgf~l~~g~l~~K~~Ri~~if~~~~~~---~~~~~~~~l~~~~~~~~~i~~~il~~w~~~~p~~~~~~~~~  596 (908)
T 6W2X_B          520 CTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMK---KKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYS  596 (908)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC----------CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECC
T ss_pred             HHHHHHHHHHHHHHHHHHHHHhHHHHHHHHcCcccc---ccccCHHHHHHHHHHHHHHHHHHHHHHHHhCccchhhhccc
Confidence            999999999999999999999999999999876543   34678889999999999999999999999999876532110


Q NP_000836.2     728 QRT----LDPEKARGVLKCDIS--DLSLICSLGYSILLMVTCTVYAIKTRGVP-ETFNEAKPIGFTMYTTCIIWLAFIPI  800 (908)
Q Consensus       728 ~~~----~~~~~~~~~~~C~~~--~~~~~~~~~~~~~ll~~~~~la~~~R~~~-~~~nes~~i~~~~~~~~~~~~~~~~~  800 (908)
                      ...    .+.........|.+.  ..|++++++|+++|+++|++|||++|++| ++|||+|+|++++|+++++|++++++
T Consensus       597 ~~~~~~~~~~~~~~~~~~C~~~~~~~~~~~~~~y~~llll~~~~la~~tR~v~~~~~nEsk~i~~a~~~~~~~~~~~~~~  676 (908)
T 6W2X_B          597 MEPDPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAV  676 (908)
T ss_dssp             CBCC-----CEECCEEEEEECSSCHHHHHHHHHHHHHHHHHHHHHHHHTSSCCCSSCCCHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CCCCCCCCCceeeceEEeecCCccHHHHHHHHHHHHHHHHHHHHHHHHhcCCCchhhccHHHHHHHHHHHHHHHHHHHHH
Confidence            000    000012445789885  37888999999999999999999999999 99999999999999999999999999


Q NP_000836.2     801 FFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKR  852 (908)
Q Consensus       801 ~~~~~~~~~~~~~~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~  852 (908)
                      +++....+   .+.+++.+++++++++++|+++|+||+|.++++|+++....
T Consensus       677 ~~~~~~~~---~~~~~~~~~~i~~~~~~~l~~if~PK~~~i~~~~~~~~~~~  725 (908)
T 6W2X_B          677 SFLTRDQP---NVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNR  725 (908)
T ss_dssp             HHHCSSSH---HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC--------
T ss_pred             HHHhcCCh---hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCcchhcccc
Confidence            88765432   35667888999999999999999999999999988765543


No 6
>6UO8_A Gamma-aminobutyric acid type B receptor; G protein-coupled receptor, GABA, GABAB; HET: BMA, QDA, NAG;{Homo sapiens}
Probab=100.00  E-value=9.3e-65  Score=605.48  Aligned_cols=682  Identities=21%  Similarity=0.300  Sum_probs=482.9  Template_Neff=10.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .+++++||+++|.+++.           ..+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+.+++.
T Consensus         3 ~~~~i~Ig~l~p~s~~~-----------~~~~~~~~a~~~Av~~iN~~~~il~g~~l~~~~~D~~~~~~~a~~~~~~l~~   71 (762)
T 6UO8_A            3 ERRAVYIGALFPMSGGW-----------PGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLY   71 (762)
T ss_dssp             CCEEEEEEEEECCSSSC-----------CCHHHHHHHHHHHHHHHTTCTTTCSSEEEEEEEEECTTCHHHHHHHHHHHHT
T ss_pred             CceeEEEEEEEecCCCC-----------CCcccHHHHHHHHHHHHHcCCCCCCCcEEEEEEccCCCCHHHHHHHHHHHHh
Confidence            45789999999998753           1356678999999999999888888999999999998875544333333322


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                                            ++++++++|+.++..+..++.+++.+++|++++.++++.++++..+|+++|+.|++..
T Consensus        72 ----------------------~~~v~~viG~~~s~~~~~va~~~~~~~ip~is~~a~s~~ls~~~~~p~~fr~~ps~~~  129 (762)
T 6UO8_A           72 ----------------------NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATL  129 (762)
T ss_dssp             ----------------------SSSCEEEEECCSHHHHHHHHHHGGGTTCEEEESSCCCGGGGCTTTCTTEEECSCCGGG
T ss_pred             ----------------------cCCcEEEEECCCHHHHHHHHHHHHHcCCEEEecccCChhhhccccCCceeecCCChhh
Confidence                                  1478899999888888888889999999999999888877766678999999999999


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      +++++++++++++|++|++++++++++....+.+++.+++. ++++.....+.     .+....++++++ .++|+|++.
T Consensus       130 ~~~a~~~~l~~~~w~~vaii~~~~~~~~~~~~~~~~~~~~~-gi~v~~~~~~~-----~~~~~~l~~l~~-~~~~vIv~~  202 (762)
T 6UO8_A          130 HNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEA-GIEITFRQSFF-----SDPAVPVKNLKR-QDARIIVGL  202 (762)
T ss_dssp             SHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHTGGG-SCEEEECCEES-----SCCHHHHHHHHH-HTCSEEEEE
T ss_pred             ccHHHHHHHHHhCCcEEEEEEeCCccchhHHHHHHHHHHHc-CcEEEEEeccc-----CCchHHHHHHHh-CCCEEEEEe
Confidence            99999999999999999999988888888888888887775 46665443332     134445666763 578988888


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSD----SWGSKIAP-----VYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLA  351 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~----~~~~~~~~-----~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~  351 (908)
                      .....+..+++++++.|+.+ ++.|+..+    .|......     ........+|.+......         .... ..
T Consensus       203 ~~~~~~~~~l~~a~~~g~~~~~~v~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~---------~~~~-~~  272 (762)
T 6UO8_A          203 FYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVM---------LNPA-NT  272 (762)
T ss_dssp             CCSHHHHHHHHHHGGGTCCSSSCEEEEESCSCTTTTSSCCTTCCCCTHHHHTTSCSEEEEEECC---------SCCS-CC
T ss_pred             CCHHHHHHHHHHHHHcCcCCCCeEEEEEcccccchhhhcCCCCCCCHHHHHHHHCCcEEEEeec---------cCCC-CC
Confidence            77777888999998888754 56777653    22211000     000111222322211100         0000 00


Q NP_000836.2     352 NNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLC  431 (908)
Q Consensus       352 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~  431 (908)
                      ....+.++.++++++... ....   +    .           ......++..+|||++++++|+++.....+..  +.+
T Consensus       273 ~~~~~~~~~~f~~~~~~~-~~~~---~----~-----------~~~~~~~~~~~yDav~~~a~al~~~~~~~~~~--~~~  331 (762)
T 6UO8_A          273 RSISNMTSQEFVEKLTKR-LKRH---P----E-----------ETGGFQEAPLAYDAIWALALALNKTSGGGGRS--GVR  331 (762)
T ss_dssp             CCTTSCCTTHHHHHHHHH-CSSC---T----T-----------TSTTCTTHHHHHHHHHHHHHHHHHHC----------C
T ss_pred             cCcCCCCHHHHHHHHHHH-HhcC---C----c-----------cCCCCccccHHHHHHHHHHHHHHHHhhcCccC--CCC
Confidence            001122333433322111 1000   0    0           01123457789999999999999986543211  000


Q NP_000836.2     432 PR----MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHR  507 (908)
Q Consensus       432 ~~----~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~~  507 (908)
                      ..    .....++.+.+.|++.+|.|.+| ++.||++|++...+.+.+++    ++.++.||.|+....    .+.|...
T Consensus       332 ~~~~~~~~~~~~~~l~~~l~~~~f~G~~G-~v~fd~~G~r~~~~~i~~~~----~~~~~~vg~~~~~~~----~~~~~~~  402 (762)
T 6UO8_A          332 LEDFNYNNQTITDQIYRAMNSSSFEGVSG-HVVFDASGSRMAWTLIEQLQ----GGSYKKIGYYDSTKD----DLSWSKT  402 (762)
T ss_dssp             TTCCCSSCCTTHHHHHHHHHTCCCBCSSS-BCCCSSSSCCCCCEEEEEEE----TTEEEEEEEECSSSC----CCCCCCC
T ss_pred             HHHcCCCCHHHHHHHHHHHHcCcccccce-eeEeCCCCCccceEEEEEEe----CCeEEEEEEEECCCC----ceeecCC
Confidence            00    01123446777888889999988 89999999998888888887    357899999986521    2344211


Q NP_000836.2     508 EHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVP  587 (908)
Q Consensus       508 ~~~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s~~~~~~~  587 (908)
                                ..|+.|.                               +|.|      ++.|   +..+..++.++.+++
T Consensus       403 ----------~~~~~g~-------------------------------~p~d------~~~~---~~~~~~~~~~~~~~~  432 (762)
T 6UO8_A          403 ----------DKWIGGS-------------------------------PPAD------QTLV---IKTFRFLSQKLFISV  432 (762)
T ss_dssp             ----------CCCGGGS-------------------------------CCCC------CCCE---EEECCCCTTHHHHHH
T ss_pred             ----------CccCCCC-------------------------------CCCC------ccee---hhccchhCHHHHHHH
Confidence                      1222221                               2333      4444   333445567778888


Q NP_000836.2     588 VFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFL------MIAAP-DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       588 ~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~------~~~~~-~~~~C~~~~~~~~~gf~  660 (908)
                      .++++++++++++++++++++|+++.+|+++|.+++++|+|++++|+++++      ++..+ +...|.+|.|++++||+
T Consensus       433 ~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~l~~~~l~g~~l~~~~~~~~~~~~~~i~~~~~~~~C~~~~~~~~~gf~  512 (762)
T 6UO8_A          433 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFS  512 (762)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHSCCSHHHHSSCTHHHHHHHHHHHHHHTTSHHHHCCTTTTTTTCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHHccCChhHhccCHHHHHHHHHHHHHHHHhHHhhCCCCCCCCccchHHHHHHHHHHHHHhHH
Confidence            899999999999999999999999999999999999999999999999986      34445 68999999999999999


Q NP_000836.2     661 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRT----LDPEKA  736 (908)
Q Consensus       661 l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~----~~~~~~  736 (908)
                      ++||++++|+||++++|++++.++..++.++++.++.+++++++++++++++|+.++|+..........+    .+....
T Consensus       513 l~~~~l~~k~~ri~~if~~~~~~~~~~~~~~~~~l~~~~~~~~~i~~~il~~w~~~~p~~~~~~~~~~~~~~~~~~~~~~  592 (762)
T 6UO8_A          513 LGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSIL  592 (762)
T ss_dssp             HHHHHHHHHHHHHHHTTSCCSSCTTCSSCSSTHHHHHHHHHHHHHHHHHHHHHHHSSCCCCEEEECCCCCCCSSSSCCEE
T ss_pred             HHHhhhhhcceEEEEEeecccccchhhcccCHHHHHHHHHHHHHHHHHHHHHHHHhCcccceeeecccCCCCccCCceEe
Confidence            9999999999999999997654322244678899999999999999999999999999976543211000    000012


Q NP_000836.2     737 RGVLKCDISD--LSLICSLGYSILLMVTCTVYAIKTRGVP-ETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYI  813 (908)
Q Consensus       737 ~~~~~C~~~~--~~~~~~~~~~~~ll~~~~~la~~~R~~~-~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  813 (908)
                      .....|.+.+  .|++++++|+++|++++++|||++|++| ++|||+|+|++++|+++++|++++++++.....+   ..
T Consensus       593 ~~~~~C~~~~~~~~~~~~~~~~~~ll~~~~~la~~tr~~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~---~~  669 (762)
T 6UO8_A          593 PQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQ---DA  669 (762)
T ss_dssp             EEEEECCCSCCTTHHHHHHHHHHHHHHHHHHHHHSCCSCCSSCSSHHHHHHHHHHHHHHHHHHHHHHHTTCCCTT---TS
T ss_pred             ceeeeeecCCchHHHHHHHHHHHHHHHHHHHHHHHhcCCCChhhccHHHHHHHHHHHHHHHHHHHHHHHHhcCCh---hH
Confidence            2356999864  7888999999999999999999999999 9999999999999999999999999987665432   35


Q NP_000836.2     814 QTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRSF  856 (908)
Q Consensus       814 ~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~~~  856 (908)
                      .+.+.+++++++++++|+++|+||+|.++++++.+......++
T Consensus       670 ~~~~~~~~i~~~~~~~l~~~f~Pk~~~~~~~~~~~~~~~~~~~  712 (762)
T 6UO8_A          670 AFAFASLAIVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMK  712 (762)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHSHHHHHHHC-------------
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccchhhhhcc
Confidence            6678889999999999999999999999999988776554443


No 7
>6UO8_B Gamma-aminobutyric acid type B receptor; G protein-coupled receptor, GABA, GABAB; HET: BMA, QDA, NAG;{Homo sapiens}
Probab=100.00  E-value=2.2e-64  Score=602.93  Aligned_cols=675  Identities=21%  Similarity=0.307  Sum_probs=484.0  Template_Neff=10.500

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      ....+++++||+++|.++....        ...+.....|+++|++++|+++ .++|+++++.+.|+++++..+.+.+.+
T Consensus         9 ~~~~~~~i~Ig~l~p~~~~~~~--------~~~g~~~~~a~~~Av~~iN~~~-~l~~~~l~~~~~D~~~~~~~a~~~~~~   79 (779)
T 6UO8_B            9 PPPSSPPLSIMGLMPLTKEVAK--------GSIGRGVLPAVELAIEQIRNES-LLRPYFLDLRLYDTECDNAKGLKAFYD   79 (779)
T ss_dssp             ----CCEEEEEEECCCCSSSSS--------SHHHHHHHHHHHHHHHHHHTTC-SSTTSEEEEEEECCTTCHHHHHHHHHH
T ss_pred             CCCCCCCeEEEEEEEcCccccC--------CcccccHHHHHHHHHHHHHhcc-CCCCcEEEEEEecCCCChHHHHHHHHH
Confidence            4566789999999999875310        0245678899999999999875 456899999999998876544433333


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      ++..                     .+++++++|+.++..+.+++.+++.+++|+|+++++++.++++..+++++|+.|+
T Consensus        80 l~~~---------------------~~~v~~viG~~~s~~~~~va~~~~~~~ip~is~~ats~~ls~~~~~p~~~rt~ps  138 (779)
T 6UO8_B           80 AIKY---------------------GPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPS  138 (779)
T ss_dssp             HHHT---------------------SCCEEEEEECCSTTHHHHHHTTCTTTTCCEEESSCCCGGGGCTTSCTTEEESSCC
T ss_pred             HHHh---------------------CCCEEEEEecCChHHHHHHHHHcCccCCEEEecccCChhHcCcccCCCceecCCC
Confidence            3221                     1368899999988888888999999999999999988888876678999999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      +..+++++++++++++|++|++++++++++....+.+++.+++. ++++.....++     .+..+.++++++ .++++|
T Consensus       139 ~~~~~~a~~~~l~~~~W~~v~ii~~~~~~~~~~~~~~~~~~~~~-gi~v~~~~~~~-----~d~~~~l~~l~~-~~~~iI  211 (779)
T 6UO8_B          139 DNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGE-DIEISDTESFS-----NDPCTSVKKLKG-NDVRII  211 (779)
T ss_dssp             TTSSHHHHHHHHTTTTCCCEEEEECSSSHHHHHHHHHHHHTSSS-SCCEEEEEECS-----SCGGGTHHHHHH-TTCCEE
T ss_pred             HhhhcHHHHHHHHHcCCCEEEEEEecchhHHHHHHHHHHHHHhC-CcEEEeeeeec-----CChhHHHHHHhh-CCcEEE
Confidence            99999999999999999999999988888888888888877765 46665443332     234556777763 588998


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVY-------------QQEEIAEGAVTILPKRASIDGFDRY  344 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~-------------~~~~~~~g~~~~~~~~~~~~~~~~~  344 (908)
                      ++......+..+++++++.|+.+ +++|+..+ |........             ......+|.+.+.........+..+
T Consensus       212 v~~~~~~~~~~~l~~a~~~g~~~~~~~wi~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~  290 (779)
T 6UO8_B          212 LGQFDQNMAAKVFCCAYEENMYGSKYQWIIPG-WYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTI  290 (779)
T ss_dssp             EEECCHHHHHHHHHHHHHTTCCSTTCEEEEEC-CCCTTTTTTSCSSSCCTTSCSHHHHTTSCSCEEEEECSSCSSCCCCS
T ss_pred             EEeCCHHHHHHHHHHHHHcCCCCCcEEEEeec-CCCcchhHhhcccccCCCccHHHHHHHHCCceeeEecCCCCCCcccc
Confidence            88877777888999998888754 57788764 322110000             0111223333222111000000000


Q NP_000836.2     345 FRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC  424 (908)
Q Consensus       345 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~  424 (908)
                                ......+ |.+.+.+...                      ...+..++.++|||++++++|++++....+
T Consensus       291 ----------~~~~~~~-~~~~~~~~~~----------------------~~~~~~~~~~~yDAv~~~a~al~~~~~~~~  337 (779)
T 6UO8_B          291 ----------SGKTPQQ-YEREYNNKRS----------------------GVGPSKFHGYAYDGIWVIAKTLQRAMETLH  337 (779)
T ss_dssp             ----------SSSCHHH-HHHHHHHHSS----------------------SCCCCSCSSTTHHHHHHHHHHHHHHHSSSC
T ss_pred             ----------CCCCHHH-HHHHHHhhcC----------------------CCCccccchHHHHHHHHHHHHHHHHHHHHH
Confidence                      0000111 1111211000                      012345678899999999999999875432


Q NP_000836.2     425 PGY----IGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLH---L  497 (908)
Q Consensus       425 ~~~----~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~---~  497 (908)
                      ...    ...+.......+..+.+++++.+|.|.+| ++.|| +|++...+.+.+++    ++.++.||.|+....   +
T Consensus       338 ~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~sG-~v~f~-~g~r~~~~~i~~~~----~~~~~~vg~~~~~~~~l~~  411 (779)
T 6UO8_B          338 ASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTG-QVVFR-NGERMGTIKFTQFQ----DSREVKVGEYNAVADTLEI  411 (779)
T ss_dssp             SHHHHHTTSCCCSCCHHHHHHHHHHHHCCCCBCSSS-BCEEE-TTEEECEEEEEEEC----SSSEEEEEEEESSSCCEEE
T ss_pred             hcCCCCCHHHcCCCCHHHHHHHHHHHHcCCccccce-eEEEe-CCceecEEEEEEEe----CCeEEEEEEEECCCCeEEE
Confidence            110    00010111224556778888889999988 89999 89998889999988    257899999986521   1


Q NP_000836.2     498 KVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKL  577 (908)
Q Consensus       498 ~~~~i~w~~~~~~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~  577 (908)
                      +...+.|.+                |.                               +|.+      ++.|   .....
T Consensus       412 ~~~~~~~~~----------------~~-------------------------------~P~d------~~~~---~~~~~  435 (779)
T 6UO8_B          412 INDTIRFQG----------------SE-------------------------------PPKD------KTII---LEQLR  435 (779)
T ss_dssp             CTTTCCCSS----------------SS-------------------------------CCCS------SCCE---EEEEC
T ss_pred             ecccceeCC----------------CC-------------------------------CCCC------Ccee---eeecc
Confidence            111223321                10                               2333      3333   23333


Q NP_000836.2     578 EWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPD-------TIICSF  650 (908)
Q Consensus       578 ~~s~~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~-------~~~C~~  650 (908)
                      .++.++.+++.+++++|++++++++++++++|+++.+|++++.+++++|+|++++|++++++++.++       ...|.+
T Consensus       436 ~~~~~~~~~~~~~~~~gi~~~~~~~~~~~~~r~~~~ik~s~~~~~~~il~g~~l~~~~~~~~~~~~~~~~~~~~~~~C~~  515 (779)
T 6UO8_B          436 KISLPLYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLDGSFVSEKTFETLCTV  515 (779)
T ss_dssp             CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTSTTCTTCCHHHHHHHHHHHHHHHHHHHHHCCCTTTTTTTSHHHHHHH
T ss_pred             cCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCChhHhcCCHHHHHHHHHHHHHHHHHHHHhcCCCCCCChhHHHHHHHh
Confidence            5677788888899999999999888999999999999999999999999999999999999887775       689999


Q NP_000836.2     651 RRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRT  730 (908)
Q Consensus       651 ~~~~~~~gf~l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~  730 (908)
                      |.|++++||+++||+|++|+||++++|++.+.+   ++.++++.++.+++++++++++++++|++++|+...........
T Consensus       516 ~~~~~~~gf~l~~~~l~~K~~ri~~if~~~~~~---~~~~~~~~l~~~~~~~~~i~~~il~~w~~~~p~~~~~~~~~~~~  592 (779)
T 6UO8_B          516 RTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMK---KKIIKDQKLLVIVGGMLLIDLCILICWQAVDPLRRTVEKYSMEP  592 (779)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHTSCCC-----CCCSCSSHHHHHHHHHHHHHHHHHHTTTTTCCCCCCCEECCCCC
T ss_pred             HHHHHHHHHHHHHHHhHHHHHhHHhHhcccccc---CcccCHHHHHHHHHHHHHHHHHHHHHHHHhCcccceeeeeecCC
Confidence            999999999999999999999999999876543   34678888999999999999999999999999876532110000


Q NP_000836.2     731 ----LDPEKARGVLKCDIS--DLSLICSLGYSILLMVTCTVYAIKTRGVP-ETFNEAKPIGFTMYTTCIIWLAFIPIFFG  803 (908)
Q Consensus       731 ----~~~~~~~~~~~C~~~--~~~~~~~~~~~~~ll~~~~~la~~~R~~~-~~~nes~~i~~~~~~~~~~~~~~~~~~~~  803 (908)
                          .+.........|.+.  ..|++++++|+++|+++|++|||++|++| ++|||+|+|++++|+++++|+++++++++
T Consensus       593 ~~~~~~~~~~~~~~~C~~~~~~~~~~~~~~y~~~ll~~~~~la~~~r~~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~  672 (779)
T 6UO8_B          593 DPAGRDISIRPLLEHCENTHMTIWLGIVYAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFL  672 (779)
T ss_dssp             CCSSCCCEEEEEECCCCCTTTTSSSHHHHHHHHHHHHHHHHHHHHHHTSCCCTTSCSSHHHHHHHHHHHHHHHHHHHHTT
T ss_pred             CCCCCCceEeeeEeeecCCChHHHHHHHHHHHHHHHHHHHHHHHHhcCCCChhhcchhHHHHHHHHHHHHHHHHHHHHHH
Confidence                000012345799885  37888999999999999999999999999 99999999999999999999999999876


Q NP_000836.2     804 TAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKR  852 (908)
Q Consensus       804 ~~~~~~~~~~~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~  852 (908)
                      ....+   ...+.+.+++++++++++|+++|+||+|.++++|+.+...+
T Consensus       673 ~~~~~---~~~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~  718 (779)
T 6UO8_B          673 TRDQP---NVQFCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNR  718 (779)
T ss_dssp             CCSCT---TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC--------
T ss_pred             hcCCc---hHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccCcchhhhcc
Confidence            65432   35567888999999999999999999999999998876644


No 8
>7C7Q_A Gamma-aminobutyric acid type B receptor; GABAB, Cryo-EM, GPCR, active, PAM; HET: FN0, 2C0, NAG;{Homo sapiens}
Probab=100.00  E-value=3.4e-62  Score=592.43  Aligned_cols=685  Identities=20%  Similarity=0.285  Sum_probs=475.7  Template_Neff=10.600

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.+++.           ..+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+.+ 
T Consensus       166 ~~~~~~i~Ig~l~p~~~~~-----------~~~~~~~~a~~~Av~~iN~~~~il~~~~l~l~~~D~~~~~~~a~~~~~~-  233 (879)
T 7C7Q_A          166 HSERRAVYIGALFPMSGGW-----------PGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYE-  233 (879)
T ss_dssp             --CCEEEEEEEECCCSSSC-----------CTHHHHHHHHHHHHHHHHHCTTTCSSEEEEEEEECCTTCHHHHHHHHHH-
T ss_pred             CccCCceEEEeEecCCCCC-----------CCccchHHHHHHHHHHHHhCCCCCCCCEEEEEEcCCCCChHHHHHHHHH-
Confidence            3456889999999998743           1356678999999999999888888999999999998876544333333 


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                         ++.                  ++++++++|+.++..+..++.+++..++|+|++.++++.++++..+++++|+.|++
T Consensus       234 ---l~~------------------~~~v~~viG~~~s~~~~~~a~~~~~~~ip~is~~a~s~~ls~~~~~~~~~r~~ps~  292 (879)
T 7C7Q_A          234 ---LLY------------------NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSA  292 (879)
T ss_dssp             ---HHT------------------SSSCEEEEEECSHHHHHHHHHHGGGTTCEEEESSCCCGGGGCTTTSTTEEESSCCG
T ss_pred             ---HHh------------------CCCeEEEEEcCChHHHHHHHHHHHhcCCEEEecccCChhhhccccCCceEEcCCCh
Confidence               322                  15788999998888777888899999999999998877777666789999999999


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      ..+++++++++++++|++|++++++++++....+.+++.+++. ++++.....+.     .+....++++++ .++|+|+
T Consensus       293 ~~~~~a~~~~l~~~~w~~v~ii~~~~~~g~~~~~~~~~~~~~~-gi~v~~~~~~~-----~~~~~~l~~l~~-~~~~vIv  365 (879)
T 7C7Q_A          293 TLHNPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEA-GIEITFRQSFF-----SDPAVPVKNLKR-QDARIIV  365 (879)
T ss_dssp             GGHHHHHHHHHHHTTCCEEEEEEESCHHHHHHHHHHHHHHHHH-TCEEEEEEEES-----SCCHHHHHHHHH-TTCCEEE
T ss_pred             hhccHHHHHHHHHhCCCEEEEEEECCCcchHHHHHHHHHHHHc-CcEEEEEeccc-----CCchHHHHHHHh-CCCEEEE
Confidence            9999999999989999999999988888888888888888775 46765443332     133455666763 5889998


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQSG-HFLWIGSD----SWGSKIAP-----VYQQEEIAEGAVTILPKRASIDGFDRYFRSRT  349 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~----~~~~~~~~-----~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~  349 (908)
                      +......+..+++++++.|+.+ ++.|+..+    .|......     ........+|.+.......         ... 
T Consensus       366 ~~~~~~~~~~~l~~a~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~---------~~~-  435 (879)
T 7C7Q_A          366 GLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVML---------NPA-  435 (879)
T ss_dssp             EECCHHHHHHHHHHHHHHTCCSSSCEEEEETTSCTTTTTSCCTTCCSCHHHHHHHSSSCEEEEECCS---------CCS-
T ss_pred             EecCHHHHHHHHHHHHHcccCCCCEEEEEecccccccccccCCCCCCCHHHHHHHHcCcEEEEeecc---------CCC-
Confidence            8877777888999998888754 46777653    22211000     0000112223222111000         000 


Q NP_000836.2     350 LANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYI-  428 (908)
Q Consensus       350 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~-  428 (908)
                      ......+.++.++++++... ....   +    .           ......++..+|||++++++|++++....+.... 
T Consensus       436 ~~~~~~~~~~~~f~~~~~~~-~~~~---~----~-----------~~~~~~~~~~~yDAv~~~a~Al~~~~~~~~~~~~~  496 (879)
T 7C7Q_A          436 NTRSISNMTSQEFVEKLTKR-LKRH---P----E-----------ETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVR  496 (879)
T ss_dssp             CCCCTTSCCHHHHHHHHHHH-SSSC---G----G-----------GSTTTTSHHHHHHHHHHHHHHHHHTC--------C
T ss_pred             CCcccCCCCHHHHHHHHHHH-HhcC---C----c-----------cCCCCcccchHHHHHHHHHHHHHHHhcccccCCCC
Confidence            00000122333333322111 1000   0    0           0112345778999999999999998754321100 


Q NP_000836.2     429 GLCPR-MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHR  507 (908)
Q Consensus       429 ~~~~~-~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~~  507 (908)
                      ..+.. .....++.+.++|++.+|.|.+| ++.||++|++...+.+.+++    ++.++.+|.|+....    .+.|...
T Consensus       497 ~~~~~~~~~~~~~~l~~~l~~~~f~G~~G-~v~fd~~G~r~~~~~i~~~~----~~~~~~vg~~~~~~~----~~~~~~~  567 (879)
T 7C7Q_A          497 LEDFNYNNQTITDQIYRAMNSSSFEGVSG-HVVFDASGSRMAWTLIEQLQ----GGSYKKIGYYDSTKD----DLSWSKT  567 (879)
T ss_dssp             CTTCCTTCCHHHHHHHHHHHTCEEEETTE-EEECCSSCCCCCEEEEEEEC----SSSEEEEEEEETTTT----EEEECSC
T ss_pred             HHHCCCCCHHHHHHHHHHHHcCcccccee-eEEeCCCCCccceEEEEEEe----CCEEEEEEEEECCCC----ceeeccC
Confidence            00000 01123456778888889999988 89999999998888888887    357899999986521    2344211


Q NP_000836.2     508 EHTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVP  587 (908)
Q Consensus       508 ~~~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s~~~~~~~  587 (908)
                                ..|+.|.                               +|.+      .+.|   ...+..++..+.+++
T Consensus       568 ----------~~w~~g~-------------------------------~p~~------~~~~---~~~~~~~~~~~~i~~  597 (879)
T 7C7Q_A          568 ----------DKWIGGS-------------------------------PPAD------QTLV---IKTFRFLSQKLFISV  597 (879)
T ss_dssp             ----------CCCTTSS-------------------------------CCCS------SCCE---EEEECCCCHHHHHHH
T ss_pred             ----------CccCCCC-------------------------------CCcc------ccee---eeecchhCHHHHHHH
Confidence                      1222221                               2333      3333   233445556777888


Q NP_000836.2     588 VFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFL------MIAAP-DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       588 ~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~------~~~~~-~~~~C~~~~~~~~~gf~  660 (908)
                      .++++++++++++++++++++|+++.+|++++.+++++|+|++++|+++++      ++..| +...|.+|.|++++||+
T Consensus       598 ~~~~~~~i~~~~~~~~~~~~~r~~~~i~~~~~~l~~~il~g~~l~~~~~~~~~~~~~~~~~~~~~~~C~~~~~~~~~~f~  677 (879)
T 7C7Q_A          598 SVLSSLGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFPFVCQARLWLLGLGFS  677 (879)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHTSSSSGGGGSCHHHHHHHHHHHHHHHHTHHHHHCCTTTSCSTTTHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHHcccChhHhccCHHHHHHHHHHHHHHHHHHHHhcCCccCCCccchhHHHHHHHHHHHHhHH
Confidence            888999998888888889999999999999999999999999999999986      34445 68899999999999999


Q NP_000836.2     661 FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRT----LDPEKA  736 (908)
Q Consensus       661 l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~----~~~~~~  736 (908)
                      ++||+|++|+||++++|++++.++.+++.++++.++.++++++++|++++++|++++|+..........+    .+....
T Consensus       678 l~~~~l~~K~~ri~~if~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~il~~w~~~~p~~~~~~~~~~~~~~~~~~~~~~  757 (879)
T 7C7Q_A          678 LGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGMDVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSIL  757 (879)
T ss_dssp             HHHSTTTHHHHHHHHHCC-----------CCTTHHHHHHHHHHHHHHHHHHHHHHHSCCEEEEEECCCCCCTTSSSCEEE
T ss_pred             HHHHHHhccceEEEEEeecccccchhhccCCHHHHHHHHHHHHHHHHHHHHHHHHhCcccceeeecccCCCCcCCCeeEe
Confidence            9999999999999999997654322234678888999999999999999999999999976543211000    000012


Q NP_000836.2     737 RGVLKCDISD--LSLICSLGYSILLMVTCTVYAIKTRGVP-ETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYI  813 (908)
Q Consensus       737 ~~~~~C~~~~--~~~~~~~~~~~~ll~~~~~la~~~R~~~-~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  813 (908)
                      .....|.+.+  .+++++++|+++|++++++|||++|++| ++|||+|+|++++|+++++|+++++++++.....   ..
T Consensus       758 ~~~~~C~~~~~~~~~~~~~~~~~~ll~~~~~la~~tR~~~~~~~nesk~i~~~~~~~~~~~~~~~~~~~~~~~~~---~~  834 (879)
T 7C7Q_A          758 PQLEHCSSRKMNTWLGIFYGYKGLLLLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQ---DA  834 (879)
T ss_dssp             EEEEEEECSSCSSHHHHHHHHHHHHHHHHHHHHHHTSSCCCSSSSCHHHHHHHHHHHHHHHHHHHHHHHHSTTCH---HH
T ss_pred             ceEeEeecCCchHHHHHHHHHHHHHHHHHHHHHHHhcCCCchhhccHHHHHHHHHHHHHHHHHHHHHHHHhcCCh---HH
Confidence            2367999864  6778899999999999999999999999 9999999999999999999999999987665432   24


Q NP_000836.2     814 QTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKRS  855 (908)
Q Consensus       814 ~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~~  855 (908)
                      .+.+.+++++++++++|+++|+||+|.++++++++..++...
T Consensus       835 ~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~~  876 (879)
T 7C7Q_A          835 AFAFASLAIVFSSYITLVVLFVPKMRRLITEVLFQGPHHHHH  876 (879)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC------------
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccCCCCCCCC
Confidence            566888999999999999999999999999998887665443


No 9
>2E4U_A Metabotropic glutamate receptor 3; G-protein-coupled receptor, neuron, central nerve; HET: GLU, NAG; 2.35A {Rattus norvegicus}
Probab=100.00  E-value=1.2e-43  Score=406.76  Aligned_cols=535  Identities=46%  Similarity=0.875  Sum_probs=346.7  Template_Neff=11.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...+++++||+++|.++.......|+......+.....|+++|++++|+++++++|+++++.+.|++++...+.+.+.++
T Consensus         9 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~g~~~~~a~~~Av~~iN~~~~~l~~~~l~~~~~D~~~~~~~a~~~~~~~   88 (555)
T 2E4U_A            9 IKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDNYLLPGVKLGVHILDTCSRDTYALEQSLEF   88 (555)
T ss_dssp             EEECCSEEEEEEECCEEECCTTCSEEEECCCCCCCHHHHHHHHHHHHHHCTTSSTTCCEEEEEEECTTCHHHHHHHHHHH
T ss_pred             eEecCCEEEEeeecceecCCCCCCccccccccCHHHHHHHHHHHHHHhcCCCCCCCCeeeEEEeeCCCCHHHHHHHHHHH
Confidence            45578999999999987543233455333345677889999999999999888889999999999988765544444443


Q NP_000836.2     120 VQALIEK-DASDVKCANGDPPIFTK-PDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       120 ~~~l~~~-~~~~~~~~~~~~~~~~~-~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +...... ......|....+.+... ..+++++||+.++..+..++.++..+++|+|++++.++.++++..+++++++.|
T Consensus        89 ~~~~~~~~~~~~~~c~~~~~~~~~~~~~~v~~viG~~~s~~~~~~~~~~~~~~ip~is~~~~~~~l~~~~~~~~~~r~~p  168 (555)
T 2E4U_A           89 VRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVP  168 (555)
T ss_dssp             HHTTC--------------------CCCCEEEEEECSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTTCTTEEESSC
T ss_pred             HHHhccCcccccccCCCCCcccccCCCCcEEEEEcCCChHHHHHHHHHhHhhCCCEEecCcCCcccCCCCcCCCccccCC
Confidence            3210000 00000000000000000 035789999988888888889999999999999887777766556899999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ++..+++++++++++++|++|++|+.+++++....+.+.+.+++. ++++.....++......++...++++++..++++
T Consensus       169 ~~~~~~~~l~~~l~~~~w~~v~~i~~~~~~g~~~~~~~~~~~~~~-~i~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v  247 (555)
T 2E4U_A          169 PDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLR-NICIATAEKVGRSNIRKSYDSVIRELLQKPNARV  247 (555)
T ss_dssp             CHHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHTT-TCEEEEEEEECTTCCHHHHHHHHHHHHTCTTCCE
T ss_pred             CHHHHHHHHHHHHHHcCCCEEEEEEEcCcchHHHHHHHHHHHHHC-CCEEEEEEEeccccccccHHHHHHHHHhCCCccE
Confidence            999999999999999999999999988888888888888887765 4666543333211112345555666632247888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      |++.+....+..+++++.+.|+  ++.|++.+.|...............+.+.+.......++|..|+....+...+.+.
T Consensus       248 vv~~~~~~~~~~~~~~~~~~~~--~~~~i~~~~~~~~~~~~~~~~~~~~g~l~~~~~~~~~~~f~~fl~~~~~~~~~~~~  325 (555)
T 2E4U_A          248 VVLFMRSDDSRELIAAANRVNA--SFTWVASDGWGAQESIVKGSEHVAYGAITLELASHPVRQFDRYFQSLNPYNNHRNP  325 (555)
T ss_dssp             EEEECCHHHHHHHHHHHHHTTC--CCEEEECTTTTTCGGGTTTCHHHHTTCEEEEECCCCCHHHHHHHHTCCTTTCTTCT
T ss_pred             EEEECCHHHHHHHHHHHHHcCC--CeEEEEeCcccccchhhcCCcceeceEEEEEEcCCCCccHHHHHHhCCCCcCCCCH
Confidence            8888777778888888887776  36788876665432110001123344444443333334455444332222223455


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTI  437 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~  437 (908)
                      ++.++|++.++|.....   ......|+..+..... ......++.++||||+++|+||+++....+......|......
T Consensus       326 ~~~~~~~~~~~c~~~~~---~~~~~~c~~~~~~~~~-~~~~~~~~~~~ydAv~~~a~aL~~~~~~~~~~~~~~c~~~~~~  401 (555)
T 2E4U_A          326 WFRDFWEQKFQCSLQNK---RNHRQVCDKHLAIDSS-NYEQESKIMFVVNAVYAMAHALHKMQRTLCPQTTKLCDAMKIL  401 (555)
T ss_dssp             THHHHHHHHTTCCCC---------CCCCTTCCCCTT-TCCCCTTHHHHHHHHHHHHHHHHHHHHHHCTTCSSCCGGGTSC
T ss_pred             HHHHHHHHHcCCccCCc---cCCCcccCCCcccCCC-CccchhhHHHHHHHHHHHHHHHHHHHhccCCCCCCCchhhccc
Confidence            67777777666532110   0011123322111100 0122345678999999999999998764332111122211111


Q NP_000836.2     438 DGKE-LLGYIRAVNFN-------GSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREH  509 (908)
Q Consensus       438 ~~~~-l~~~l~~~~f~-------G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~~~~  509 (908)
                      ++.. +.+.|++..|.       |.+| .+.||++|++...|.|++++..++...++.||.|+....++...+.|.++  
T Consensus       402 ~~~~~~~~~l~~~~f~~~~~~~~g~~g-~v~fd~~G~~~~~~~i~~~~~~~~~~~~~~vg~~~~~~~~~~~~i~W~~~--  478 (555)
T 2E4U_A          402 DGKKLYKEYLLKIQFTAPFNPNKGADS-IVKFDTFGDGMGRYNVFNLQQTGGKYSYLKVGHWAETLSLDVDSIHWSRN--  478 (555)
T ss_dssp             CHHHHHHHHTTCEEECCSSSCCSSSCC-EEECCTTSCCCCCEEEEEEECTTSSCEEEEEEEESSSEECCGGGCCCTTS--
T ss_pred             ChhHHHHHHHHhCcccCCCCCCCCCCC-eeEeCCCCCCCceEEEEEEEeeCCeEEEEEEEEeCCcEEEecccccccCC--
Confidence            2232 44677777773       6677 89999999998889999887432223688999998654344346889753  


Q NP_000836.2     510 THPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWA  584 (908)
Q Consensus       510 ~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s~~~~  584 (908)
                      ..|.++|+.+|++|++|...+++.|||+|..|++++++++.++|.+||.++|||.+++.|.+++..|+.|.+++.
T Consensus       479 ~~P~s~Cs~~C~~G~~k~~~~~~~Cc~~C~~C~~~~~~~~~~~C~~Cp~~~~~n~~~~~C~~~~~~~L~~~~~~~  553 (555)
T 2E4U_A          479 SVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLVDEFTCMDCGPGQWPTADLSGCYNLPEDYIKWEDALV  553 (555)
T ss_dssp             SCCCCCSSCCCCTTTEEEECCSSSSCCEEEECCTTEEEEETTEEEECCTTEEECTTSSSEEECCC----------
T ss_pred             CCCcceeeCCCCCCceeecCCCCcccceeeecccceeecCceeecCCCCCcccCCCCCCeEeccccccCcccCCC
Confidence            568999999999999988766678999999999999998789999999999999999999999999999887653


No 10
>2E4X_B Metabotropic glutamate receptor 3; G-protein-coupled receptor, neuron, central nerve; HET: C5B, NAG; 2.75A {Rattus norvegicus}
Probab=100.00  E-value=1.2e-43  Score=406.76  Aligned_cols=535  Identities=46%  Similarity=0.875  Sum_probs=347.2  Template_Neff=11.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...+++++||+++|.++.......|+......+.....|+++|++++|+++++++|+++++.+.|++++...+.+.+.++
T Consensus         9 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~g~~~~~a~~~Av~~iN~~~~~l~~~~l~~~~~D~~~~~~~a~~~~~~~   88 (555)
T 2E4X_B            9 IKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDNYLLPGVKLGVHILDTCSRDTYALEQSLEF   88 (555)
T ss_dssp             EEECCSEEEEEEECCEEECCTTCSEEEECCCCCCCHHHHHHHHHHHHTTCSSSSTTCCEEEEEEECTTCHHHHHHHHHHH
T ss_pred             eEecCCEEEEeeecceecCCCCCCccccccccCHHHHHHHHHHHHHHhcCCCCCCCCeeeEEEeeCCCCHHHHHHHHHHH
Confidence            45578999999999987543233455333345677889999999999999888889999999999988765544444443


Q NP_000836.2     120 VQALIEK-DASDVKCANGDPPIFTK-PDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       120 ~~~l~~~-~~~~~~~~~~~~~~~~~-~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +...... ......|....+.+... ..+++++||+.++..+..++.++..+++|+|++++.++.++++..+++++++.|
T Consensus        89 ~~~~~~~~~~~~~~c~~~~~~~~~~~~~~v~~viG~~~s~~~~~~~~~~~~~~ip~is~~~~~~~l~~~~~~~~~~r~~p  168 (555)
T 2E4X_B           89 VRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVP  168 (555)
T ss_dssp             HHHTC--------------------CCCCEEEEEECSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTTCTTEEESSC
T ss_pred             HHHhccCcccccccCCCCCcccccCCCCcEEEEEcCCChHHHHHHHHHhHhhCCCEEecCcCCcccCCCCcCCCccccCC
Confidence            3210000 00000000000000000 035789999988888888889999999999999887777766556899999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ++..+++++++++++++|++|++|+.+++++....+.+.+.+++. ++++.....++......++...++++++..++++
T Consensus       169 ~~~~~~~~l~~~l~~~~w~~v~~i~~~~~~g~~~~~~~~~~~~~~-~i~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v  247 (555)
T 2E4X_B          169 PDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLR-NICIATAEKVGRSNIRKSYDSVIRELLQKPNARV  247 (555)
T ss_dssp             CHHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHT-TCEEEEEEEECTTCCHHHHHHHHHHHHTCTTCCE
T ss_pred             CHHHHHHHHHHHHHHcCCCEEEEEEEcCcchHHHHHHHHHHHHHC-CCEEEEEEEeccccccccHHHHHHHHHhCCCccE
Confidence            999999999999999999999999988888888888888887765 4666543333211112345555666632247888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      |++.+....+..+++++.+.|+  ++.|++.+.|...............+.+.+.......++|..|+....+...+.+.
T Consensus       248 vv~~~~~~~~~~~~~~~~~~~~--~~~~i~~~~~~~~~~~~~~~~~~~~g~l~~~~~~~~~~~f~~fl~~~~~~~~~~~~  325 (555)
T 2E4X_B          248 VVLFMRSDDSRELIAAANRVNA--SFTWVASDGWGAQESIVKGSEHVAYGAITLELASHPVRQFDRYFQSLNPYNNHRNP  325 (555)
T ss_dssp             EEEECCHHHHHHHHHHHHHTTC--CCEEEECTTTTTCSTTTTTCTTTSTTCEEEEECCCCCHHHHHHHHTCCTTTCTTCT
T ss_pred             EEEECCHHHHHHHHHHHHHcCC--CeEEEEeCcccccchhhcCCcceeceEEEEEEcCCCCccHHHHHHhCCCCcCCCCH
Confidence            8888777778888888887776  36788876665432110001123344444443333334455444332222223455


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTI  437 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~  437 (908)
                      ++.++|++.++|.....   ......|+..+..... ......++.++||||+++|+||+++....+......|......
T Consensus       326 ~~~~~~~~~~~c~~~~~---~~~~~~c~~~~~~~~~-~~~~~~~~~~~ydAv~~~a~aL~~~~~~~~~~~~~~c~~~~~~  401 (555)
T 2E4X_B          326 WFRDFWEQKFQCSLQNK---RNHRQVCDKHLAIDSS-NYEQESKIMFVVNAVYAMAHALHKMQRTLCPQTTKLCDAMKIL  401 (555)
T ss_dssp             THHHHHHHHTTCCSSSS---SSCCCCCCTTCCCCTT-TCCCCTTHHHHHHHHHHHHHHHHHHHHHHCCSCSSCCGGGSSC
T ss_pred             HHHHHHHHHcCCccCCc---cCCCcccCCCcccCCC-CccchhhHHHHHHHHHHHHHHHHHHHhccCCCCCCCchhhccc
Confidence            67777777666532110   0011123322111100 0122345678999999999999998764332111122211111


Q NP_000836.2     438 DGKE-LLGYIRAVNFN-------GSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHREH  509 (908)
Q Consensus       438 ~~~~-l~~~l~~~~f~-------G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~~~~  509 (908)
                      ++.. +.+.|++..|.       |.+| .+.||++|++...|.|++++..++...++.||.|+....++...+.|.++  
T Consensus       402 ~~~~~~~~~l~~~~f~~~~~~~~g~~g-~v~fd~~G~~~~~~~i~~~~~~~~~~~~~~vg~~~~~~~~~~~~i~W~~~--  478 (555)
T 2E4X_B          402 DGKKLYKEYLLKIQFTAPFNPNKGADS-IVKFDTFGDGMGRYNVFNLQQTGGKYSYLKVGHWAETLSLDVDSIHWSRN--  478 (555)
T ss_dssp             CHHHHHHHHTTCCEECTTTSCCSSSCC-EECCCSSSCCCCCEEEEEEECTTSSCEEEEEEEESSSEECCGGGCCCGGG--
T ss_pred             ChhHHHHHHHHhCcccCCCCCCCCCCC-eeEeCCCCCCCceEEEEEEEeeCCeEEEEEEEEeCCcEEEecccccccCC--
Confidence            2232 44677777773       6677 89999999998889999887432223688999998654344346889753  


Q NP_000836.2     510 THPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWA  584 (908)
Q Consensus       510 ~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s~~~~  584 (908)
                      ..|.++|+.+|++|++|...+++.|||+|..|++++++++.++|.+||.++|||.+++.|.+++..|+.|.+++.
T Consensus       479 ~~P~s~Cs~~C~~G~~k~~~~~~~Cc~~C~~C~~~~~~~~~~~C~~Cp~~~~~n~~~~~C~~~~~~~L~~~~~~~  553 (555)
T 2E4X_B          479 SVPTSQCSDPCAPNEMKNMQPGDVCCWICIPCEPYEYLVDEFTCMDCGPGQWPTADLSGCYNLPEDYIKWEDALV  553 (555)
T ss_dssp             SCCCCCSSCCCCSSSCEEECCSSSSCCEEECCCTTEEEEETTEEEECCTTEEECTTSSSEEECCC----------
T ss_pred             CCCcceeeCCCCCCceeecCCCCcccceeeecccceeecCceeecCCCCCcccCCCCCCeEeccccccCcccCCC
Confidence            568999999999999988766678999999999999998789999999999999999999999999999887653


No 11
>6N50_A Metabotropic glutamate receptor 5, Nanobody; Cell Surface Receptor, SIGNALING PROTEIN; HET: NAG, QUS; 3.751A {Homo sapiens}
Probab=100.00  E-value=4.1e-43  Score=405.56  Aligned_cols=536  Identities=41%  Similarity=0.786  Sum_probs=353.0  Template_Neff=10.900

Q NP_000836.2      36 YAHSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTY  111 (908)
Q Consensus        36 ~~~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~  111 (908)
                      .......+++++||+++|.++...    ....|+......+.....|+++|++++|+++++++|+++++++.|+++++..
T Consensus        42 ~~~~~~~~~~i~Ig~l~p~~~~~~~~~~~~~~cg~~~~~~g~~~~~a~~~Ai~~iN~~~~~l~~~~l~~~i~D~~~~~~~  121 (596)
T 6N50_A           42 RRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAV  121 (596)
T ss_pred             cceeeEcCCCEEEEEEeecccCCCCCCCCcCCcccccccccHHHHHHHHHHHHHHHcCCCCCCCCeeEEEEEeCCCCHHH
Confidence            334456789999999999985311    1234553222356778899999999999998888899999999999887655


Q NP_000836.2     112 ALEQSLTFVQALIEKD---ASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTR  188 (908)
Q Consensus       112 a~~~~~~~~~~l~~~~---~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~  188 (908)
                      +.+.+.+++.......   .....|.+.++.+....++++++||+.++..+..++.++...++|+|++++.++.++++..
T Consensus       122 a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~aviG~~~s~~~~~~~~~~~~~~ip~is~~~~~~~ls~~~~  201 (596)
T 6N50_A          122 ALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTL  201 (596)
T ss_pred             HHHHHHHHHhcCCCCccccccceecCCCCccccccCCCeeEEECCCChHHHHHHHHHHHHhCCCeeeccCCChhhCCCCC
Confidence            5444444432100000   0000000000000011257889999988877778888899999999999887777666556


Q NP_000836.2     189 YDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKR  268 (908)
Q Consensus       189 ~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~  268 (908)
                      +++++++.|++..++.++++++++++|++|++|+.+++++....+.+++.+++. ++++.....+.......++...+++
T Consensus       202 ~~~~~r~~p~~~~~~~al~~~l~~~~w~~v~ii~~~~~~g~~~~~~~~~~~~~~-~~~i~~~~~~~~~~~~~~~~~~~~~  280 (596)
T 6N50_A          202 FKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKE-GICIAHSYKIYSNAGEQSFDKLLKK  280 (596)
T ss_pred             CCcccccCCCHHHHHHHHHHHHHHhCCCEEEEEEecCccchHHHHHHHHHHHHC-CcEEEEEEEeCCCCCccchHHHHHH
Confidence            899999999999999999999998999999999988788888888888888775 4666543322211122345566676


Q NP_000836.2     269 LLE-TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRS  347 (908)
Q Consensus       269 l~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~  347 (908)
                      +++ ..+.++|++......+..+++++.+.|+.+++.|++.+.|...............+.+.+.......++|..|+..
T Consensus       281 i~~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~I~~~~~~~~~~~~~~~~~~~~g~l~~~~~~~~~~~f~~f~~~  360 (596)
T 6N50_A          281 LTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLK  360 (596)
T ss_pred             HHHcCCCcEEEEEECCHHHHHHHHHHHHHcCCCCCEEEEEecCccccccccCCCccccccccccCCCCCCCCCHHHHHHh
Confidence            653 1244555655556667788888888887544667777655432211000111233434443333334445555443


Q NP_000836.2     348 RTLANNRRNVWFAEFWEENFGCKLGSHGKR-NSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG  426 (908)
Q Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~  426 (908)
                      ..+...+.+.++.++|++.++|........ ..+...|+.......  ......++.++||||+++|+|++++....+..
T Consensus       361 ~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~ydAV~~~a~al~~~~~~~~~~  438 (596)
T 6N50_A          361 LRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKT--HHVQDSKMGFVINAIYSMAYGLHNMQMSLCPG  438 (596)
T ss_pred             cCCCCCCCCHHHHHHHHHHcCCCCCCCccccccCCCCCCCCccccc--CCCCccchHHHHHHHHHHHHHHHHHHhccCCC
Confidence            322223345677788877766532210000 001112332211110  01123456789999999999999987543321


Q NP_000836.2     427 YIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVEDMQW  504 (908)
Q Consensus       427 ~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~~i~w  504 (908)
                      ....|......++..+.++|++.+|.|.+|..+.||++|++...|.|++++..+ +...++.||.|+... .++ ..+.|
T Consensus       439 ~~~~c~~~~~~~~~~l~~~l~~~~f~g~~G~~v~fd~~G~~~~~y~i~~~~~~~~~~~~~~~VG~~~~~~l~~~-~~i~W  517 (596)
T 6N50_A          439 YAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMD-DDEVW  517 (596)
T ss_pred             CCCCCccCCCCCHHHHHHHHhcCceecCCCCeEEeCCCCCCCCCEEEEEEEEcCCCcEEEEEEEEEcCCceEEe-cceec
Confidence            111222112235566778899899999888349999999998899999998532 223689999998652 122 13689


Q NP_000836.2     505 AHREHTHPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIK  576 (908)
Q Consensus       505 ~~~~~~~p~s~Cs~~c~~G~~k~~~~~-~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~  576 (908)
                      .++ ...|.++|+++|++|++|...++ +.|||+|.+|++++++++.++|.+||.++|||++++.|.+++...
T Consensus       518 ~~~-~~~P~s~Cs~~C~~G~~~~~~~~~~~CC~~C~~C~~~~~s~~~~~C~~Cp~~~~~n~~~t~C~~~~~~~  589 (596)
T 6N50_A          518 SKK-SNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQH  589 (596)
T ss_pred             CCC-CCCCCceecCCCCCCceeCCCCCCCCCCcceecCCCCceeCCCCceecCCCCcCCCCCCCCEEEccCCc
Confidence            753 36699999999999999988777 789999999999999987799999999999999999998776543


No 12
>6N4Y_C Metabotropic glutamate receptor 5, Nanobody; Cell Surface Receptor Nanobody, MEMBRANE; HET: FUC, MAN, NAG, BMA; 3.262A {Homo sapiens}
Probab=100.00  E-value=4.4e-43  Score=405.35  Aligned_cols=536  Identities=41%  Similarity=0.786  Sum_probs=309.2  Template_Neff=10.900

Q NP_000836.2      36 YAHSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTY  111 (908)
Q Consensus        36 ~~~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~  111 (908)
                      .......+++++||+++|.++...    ....|+......+.....|+++|++++|+++++++|+++++++.|++++...
T Consensus        42 ~~~~~~~~~~i~Ig~l~p~~~~~~~~~~~~~~cg~~~~~~g~~~~~a~~~Av~~iN~~~~~l~~~~l~~~i~D~~~~~~~  121 (596)
T 6N4Y_C           42 RRVVAHMPGDIIIGALFSVHHQPTVDKVHERKCGAVREQYGIQRVEAMLHTLERINSDPTLLPNITLGCEIRDSCWHSAV  121 (596)
T ss_dssp             -CCCEEECCSEEEEEEECCBCCCCTTTTTTTCCCSBCCCCCCHHHHHHHHHHHHHHHCSSSSTTCCEEEEEEECTTCHHH
T ss_pred             CeEEEEecCCEEEEeeeecccCCCccccccCCccccccccCHHHHHHHHHHHHHHhcCCCCCCCCeeeeEEeeCCCCHHH
Confidence            334456789999999999985210    1234553222456778899999999999998888899999999999887655


Q NP_000836.2     112 ALEQSLTFVQALIEKD---ASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTR  188 (908)
Q Consensus       112 a~~~~~~~~~~l~~~~---~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~  188 (908)
                      +.+.+.+++.......   .....|.+.++.+....++++++||+.++..+..++.++...++|+|++++.++.++++..
T Consensus       122 a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~aviG~~~s~~~~~~~~~~~~~~ip~is~~~~~~~l~~~~~  201 (596)
T 6N4Y_C          122 ALEQSIEFIRDSLISSEEEEGLVRCVDGSSSSFRSKKPIVGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSMDLSDKTL  201 (596)
T ss_dssp             HHHHHHHHHTGGGC-------------------CCCCCEEEEECCSSHHHHHHHHHHHTTTTCCEEESSCCCGGGGCTTT
T ss_pred             HHHHHHHHHHHhcCCcccccceeeccCCCcccccCCCCeEEEECCCCcHHHHHHHHHHHHhCCCEEeccCCCcccCCccc
Confidence            5444444432100000   0000000000000001257889999988877778888899999999999887777766556


Q NP_000836.2     189 YDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKR  268 (908)
Q Consensus       189 ~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~  268 (908)
                      +++++++.|++..++.++++++++++|++|++|+.++.++....+.+++.+++. ++++.....+.......++...+++
T Consensus       202 ~~~~~r~~p~~~~~~~al~~~l~~~~w~~v~ii~~~~~~g~~~~~~~~~~~~~~-~~~i~~~~~~~~~~~~~~~~~~~~~  280 (596)
T 6N4Y_C          202 FKYFMRVVPSDAQQARAMVDIVKRYNWTYVSAVHTEGNYGESGMEAFKDMSAKE-GICIAHSYKIYSNAGEQSFDKLLKK  280 (596)
T ss_dssp             CTTEEESSCCHHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEECTTSHHHHHHHHHHH
T ss_pred             CCcccccCCCHHHHHHHHHHHHHHcCCCEEEEEEeCCcchHHHHHHHHHHHHHc-CceEEEEEEecccCChHHHHHHHHH
Confidence            899999999999999999999988999999999988788888888888888775 4666543322211122345566666


Q NP_000836.2     269 LLE-TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRS  347 (908)
Q Consensus       269 l~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~  347 (908)
                      +++ ..+.++|++......+..+++++.+.|+..++.|++.+.|...............+.+.+.......+.|..|+..
T Consensus       281 i~~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~I~~~~~~~~~~~~~~~~~~~~g~l~~~~~~~~~~~f~~fl~~  360 (596)
T 6N4Y_C          281 LTSHLPKARVVACFCEGMTVRGLLMAMRRLGLAGEFLLLGSDGWADRYDVTDGYQREAVGGITIKLQSPDVKWFDDYYLK  360 (596)
T ss_dssp             HHHHTTTCCEEEEECCHHHHHHHHHHHHHTTCTTSCEEEECGGGSSCHHHHTTCHHHHTTCEEEEECCCCCHHHHHHHTT
T ss_pred             HHhcCCCeeEEEEECChHHHHHHHHHHHHhCCCCCEEEEEecccccccccccccccccccceeeeccCCCCccHHHHHHh
Confidence            653 1244555655556667788998888887544667777655432211000111223334333333333445555433


Q NP_000836.2     348 RTLANNRRNVWFAEFWEENFGCKLGSHGKR-NSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG  426 (908)
Q Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~  426 (908)
                      ..+...+.+.++.++|++.++|........ ......|+.......  ......++.++||||+++|+|++++....+..
T Consensus       361 l~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~ydAV~~~a~al~~~~~~~~~~  438 (596)
T 6N4Y_C          361 LRPETNHRNPWFQEFWQHRFQCRLEGFPQENSKYNKTCNSSLTLKT--HHVQDSKMGFVINAIYSMAYGLHNMQMSLCPG  438 (596)
T ss_dssp             CCTTTCCSCTTHHHHHHHHTTEECTTCTTCCTTCSEECCTTCCTTT--TCCCCTTHHHHHHHHHHHHHHHHHHHHHHSTT
T ss_pred             cCcccCCCCHHHHHHHHHHcCCCCCCCCcccccccccCCCcceecc--cccccccHHHHHHHHHHHHHHHHHHHhhhCCC
Confidence            322223345677788877666532110000 001112332211110  01123456679999999999999987543321


Q NP_000836.2     427 YIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVEDMQW  504 (908)
Q Consensus       427 ~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~~i~w  504 (908)
                      ....|......++..+.++|++.+|.|.+|..+.||++|++...|.|.+++..+ +...++.||.|+... .++ ..+.|
T Consensus       439 ~~~~c~~~~~~~~~~l~~~l~~~~f~g~~G~~v~fd~~G~~~~~y~i~~~~~~~~~~~~~~~VG~~~~~~l~~~-~~i~W  517 (596)
T 6N4Y_C          439 YAGLCDAMKPIDGRKLLESLMKTNFTGVSGDTILFDENGDSPGRYEIMNFKEMGKDYFDYINVGSWDNGELKMD-DDEVW  517 (596)
T ss_dssp             CSSCCGGGSSCCHHHHHHHHHTCEEECTTSCEEECCTTSCCCCEEEEEEEEEEETTEEEEEEEEEEETTEEEEC-TTC--
T ss_pred             CCCCccccCCCCHHHHHHHHhcCeeecCCCCEEEeCCCCCCCcceEEEEEEEcCCCeeEEEEEEEEeCCceEEc-ccccc
Confidence            112222112234566778899899999888349999999998899999998532 223689999998652 122 13689


Q NP_000836.2     505 AHREHTHPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIK  576 (908)
Q Consensus       505 ~~~~~~~p~s~Cs~~c~~G~~k~~~~~-~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~  576 (908)
                      .++ ...|.++|+.+|++|++|...++ +.|||+|.+|++++++++.++|.+||.++|||++++.|.+++...
T Consensus       518 ~~~-~~~P~s~Cs~~C~~G~~k~~~~~~~~CC~~C~~C~~~~~s~~~~~C~~Cp~~~~~n~~~t~C~~~~~~~  589 (596)
T 6N4Y_C          518 SKK-SNIIRSVCSEPCEKGQIKVIRKGEVSCCWTCTPCKENEYVFDEYTCKACQLGSWPTDDLTGCDLIPVQH  589 (596)
T ss_dssp             -------CCCCSSCCC----CEEECCSSCTTCCEEEC------------------------------------
T ss_pred             ccC-CCCcceeecCCCCCCeEEeeeCCCCccccceeecCCCeEecCCceeccCCCCcccCccCCCeEEccCCc
Confidence            763 36699999999999999988777 789999999999999987799999999999999999998776543


No 13
>5K5S_B Extracellular calcium-sensing receptor; Venus Flytrap module, cysteine-rich domain; HET: TRP, PO4, NAG; 2.6A {Homo sapiens}
Probab=100.00  E-value=1.3e-42  Score=402.94  Aligned_cols=534  Identities=32%  Similarity=0.555  Sum_probs=352.3  Template_Neff=10.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGER----------GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSR  108 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~----------~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~  108 (908)
                      .....++++||+++|.++....          ...|+... ..+.+...|+.+|++++|+++++++|+++++.+.|++++
T Consensus        25 ~~~~~~~i~Ig~l~p~~~~~~~~~~~~~~~~~~~~c~~~~-~~~~~~~~a~~~Av~~iN~~~~~l~~~~l~~~~~D~~~~  103 (615)
T 5K5S_B           25 RAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYN-FRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNT  103 (615)
T ss_dssp             EEEECCSEEEEEEECSBSCBCCCCCCCSSCCCCCCBCSBC-HHHHHHHHHHHHHHHHHHHCSSSCSSCCEEEEEEECTTC
T ss_pred             ceEecCCEEEEeeeeceecccCCCCCcccCCCcccceeec-cccHHHHHHHHHHHHHHhcCCCCCCCCceeEEEEcCCCC
Confidence            3567789999999999874321          12343211 245678899999999999998888999999999999887


Q NP_000836.2     109 DTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTR  188 (908)
Q Consensus       109 ~~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~  188 (908)
                      ...+.+.+.+++...    .....+....+.+....+++.++||+.++..+..++.++...++|+|++.+.++.++++..
T Consensus       104 ~~~a~~~~~~l~~~~----~~~~~~~~~~~~~~~~~~~v~~viG~~~s~~~~~~~~~~~~~~iP~is~~~~~~~l~~~~~  179 (615)
T 5K5S_B          104 VSKALEATLSFVAQN----KIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQ  179 (615)
T ss_dssp             HHHHHHHHHHHTTTT----GGGC-------------CCEEEEECCSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCTTT
T ss_pred             HHHHHHHHHHHHhcC----CccCCCccccccCCCCCCCeEEEEcCCChHHHHHHHHHHcccCCCeEeccccCcccCCccc
Confidence            655544444443211    0000000000011111135678999988877778889999999999999887777766557


Q NP_000836.2     189 YDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKR  268 (908)
Q Consensus       189 ~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~  268 (908)
                      +++++++.|++..++.++++++++++|++|++|+.++.++....+.+++.+++. ++++.....+....+..+....+++
T Consensus       180 ~~~~~r~~p~~~~~~~al~~~l~~~~w~~v~iv~~~~~~g~~~~~~l~~~~~~~-gi~i~~~~~~~~~~~~~~~~~~~~~  258 (615)
T 5K5S_B          180 FKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEER-DICIDFSELISQYSDEEEIQHVVEV  258 (615)
T ss_dssp             CTTEEESSCCTHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHT-TCEEEEEEEECTTCCHHHHHHHHHH
T ss_pred             CCCccccCCChHHHHHHHHHHHHHcCCcEEEEEEEcCccchHHHHHHHHHHHHC-CcEEEEEEeecCCCCHHHHHHHHHH
Confidence            899999999999999999999999999999999988788888888888888775 4676543333211122345556666


Q NP_000836.2     269 LLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPV-YQQEEIAEGAVTILPKRASIDGFDRYFRS  347 (908)
Q Consensus       269 l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~-~~~~~~~~g~~~~~~~~~~~~~~~~~~~~  347 (908)
                      ++. .++++|++.+....+..+++++.+.|+.+ ..|+..+.|....... ........|.+.+.......++|..|+..
T Consensus       259 l~~-~~~~vvi~~~~~~~~~~~l~~~~~~~~~~-~~~i~~~~~~~~~~~~~~~~~~~~~g~l~~~~~~~~~~~f~~f~~~  336 (615)
T 5K5S_B          259 IQN-STAKVIVVFSSGPDLEPLIKEIVRRNITG-KIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKK  336 (615)
T ss_dssp             HHT-CCCCEEEEECCHHHHHHHHHHHHHTTCCC-CEEEECTTTTTCTTTCCGGGHHHHTTCEEEEECCBCCTTHHHHHHT
T ss_pred             HHh-CCCeEEEEeCCchhHHHHHHHHHHcCCCC-CEEEEehhHhcchhccCccccceeceEEEEEeecccCccHHHHHHH
Confidence            653 57899888877777888888888888753 5788776664432100 00112334555555444455566666544


Q NP_000836.2     348 RTLANNRRNVWFAEFWEENFGCKLGSHGKR----------------------NSHIKKCTGLERIARD----SSYEQEGK  401 (908)
Q Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------------------~~~~~~c~~~~~~~~~----~~~~~~~~  401 (908)
                      ..+.....+.++.++|++.+.|........                      ..+...|++.+.+...    .......+
T Consensus       337 ~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~C~~~~~~~~~~~~~~~~~~~~~  416 (615)
T 5K5S_B          337 VHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSQSSTAFRPLCTGDENINSVETPYIDYTHLRI  416 (615)
T ss_dssp             CCTTTCSSBTTHHHHHHHHTTCBC-------------------------------CCBCCTTCCSTTSCCTTTCCSCBSH
T ss_pred             hCcccCCCChHHHHHHHHHhCCcCCCCCCCCCCchhhccCCcccCCcccCCCCCCCCCCCCCCCcccCCCCccccccccc
Confidence            332223345567777777666542210000                      0011123322211000    00112245


Q NP_000836.2     402 VQFVIDAVYSMAYALHNMHKDLCPGY---IGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQI  478 (908)
Q Consensus       402 ~~~~yDAv~~la~Al~~~~~~~~~~~---~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~  478 (908)
                      +.++||||+++|+||+++..+.+...   ...|.......++.+.+.|++.+|.|.+|+.|.||++|++...|.|++++.
T Consensus       417 ~~~~ydAV~~~A~aL~~~~~~~~~~~~~~~~~c~~~~~~~~~~l~~~l~~~~f~g~~gg~v~fd~~G~~~~~y~I~~~~~  496 (615)
T 5K5S_B          417 SYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLQFTNNMGEQVTFDECGDLVGNYSIINWHL  496 (615)
T ss_dssp             HHHHHHHHHHHHHHHHHHHTCCTTSCCBTTTBCCCTTSCCHHHHHHHHHTCEEECTTSCEEECCTTSCCCCCEEEEEEEE
T ss_pred             hhHHHHHHHHHHHHHHHHHhcCCCCCCCCCCCcccccccChHHHHHHHhcCeeeCCCCCEEEECCCCCCCceEEEEEEEe
Confidence            67899999999999999976543210   122221112234457788888899987644899999999988999999874


Q NP_000836.2     479 TN--KSTEYKVIGHWTNQL------HLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQV-  548 (908)
Q Consensus       479 ~~--~~~~~~~Vg~~~~~~------~~~~~~i~w~~~~~~~p~s~Cs~~c~~G~~k~~~~~-~~Cc~~c~~C~~~~~~~-  548 (908)
                      .+  +...++.||.|+...      .++...+.|.++...+|.++|+.+|++|+++...++ +.|||+|.+|+++++++ 
T Consensus       497 ~~~~~~~~~~~Vg~~~~~~~~~~~l~~~~~~i~W~~~~~~~P~s~Cs~~C~~G~~~~~~~~~~~CC~~C~~C~~~~~s~~  576 (615)
T 5K5S_B          497 SPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDE  576 (615)
T ss_dssp             CTTTCSEEEEEEEEECSSSCTTSSEEECGGGCCBTTTBCSCCCCCSSCCCCTTEEEEECSSSCTTCEEEEECCTTEECCS
T ss_pred             CCCCCCEEEEEEEEEEeecCCCCeEEEehhheecCCCCCCCCeeeecCCCCcCceecccCCCCcccceeeeCCCCcEECC
Confidence            31  123588999998532      123335789864456699999999999999877666 68999999999999997 


Q NP_000836.2     549 -DELSCELCPLDQRPNMNRTGCQLIPIIKLEWH  580 (908)
Q Consensus       549 -~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s  580 (908)
                       +.++|.+||.++|||++++.|.+++..|+.|.
T Consensus       577 ~~~~~C~~Cp~~~~~n~~~t~C~~~~~~~l~~~  609 (615)
T 5K5S_B          577 TDASACNKCPDDFWSNENHTSCIAKEIEFLSDY  609 (615)
T ss_dssp             TTCSSCEECCTTEEECTTSSSEEETC-------
T ss_pred             CCcccccCCCCCceecCCCCcEEecEEEeeccC
Confidence             57999999999999999999999988888776


No 14
>5KZQ_A Metabotropic glutamate receptor 2; mGluR2, antagonist, antidepressent, SIGNALING PROTEIN; HET: NAG, 6YS; 2.8A {Homo sapiens}
Probab=100.00  E-value=1.7e-42  Score=398.18  Aligned_cols=529  Identities=44%  Similarity=0.837  Sum_probs=347.9  Template_Neff=11.000

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      .....+++++||+++|.+........|+......+.....|+++|++++|+++++++|+++++++.|++++...+.+.+.
T Consensus        24 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~Ai~~iN~~~~~l~~~~l~~~~~D~~~~~~~a~~~~~  103 (570)
T 5KZQ_A           24 KVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQAL  103 (570)
T ss_pred             cceEecCCEEEEEeeehhccCCCccccccccCCccHHHHHHHHHHHHHHhcCCCCCCCCeeEEEEEeCCCCHHHHHHHHH
Confidence            34677889999999999832211224443222345678899999999999988888999999999999877554444444


Q NP_000836.2     118 TFVQALIEKD--ASDVKCANGDPPIFTK-PDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSR  194 (908)
Q Consensus       118 ~~~~~l~~~~--~~~~~~~~~~~~~~~~-~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~  194 (908)
                      +++.......  .....|...++.+... .++++++||+.++..+..++.++..+++|+|++.+.++.++++..++++++
T Consensus       104 ~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~viG~~~s~~~~~~a~~~~~~~ip~is~~~~~~~ls~~~~~~~~~r  183 (570)
T 5KZQ_A          104 DFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFAR  183 (570)
T ss_pred             HHHhcccCCCCCCCceecCCCCcccCCCCCCCceEEECCCChHHHHHHHHHhhhhCCCeeecCCCChhhCCcccCCccee
Confidence            4432100000  0000000000000000 136889999988877778888999999999999887777766556899999


Q NP_000836.2     195 VVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       195 ~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      +.|++..+++++++++++++|++|++|++++.++....+.+++.+++. ++++.....++......++...+++++...+
T Consensus       184 ~~p~~~~~~~al~~~l~~~~w~~v~il~~~~~~g~~~~~~~~~~~~~~-~i~i~~~~~~~~~~~~~~~~~~~~~l~~~~~  262 (570)
T 5KZQ_A          184 TVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARAR-NICVATSEKVGRAMSRAAFEGVVRALLQKPS  262 (570)
T ss_pred             cCCChHHHHHHHHHHHHHhCCcEEEEEEecChhhHHHHHHHHHHHHHc-CcEEEEEEEcCCCCCCcccHHHHHHHHHhCC
Confidence            999999999999999999999999999988788888888888887775 4666543333211122345555666642247


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNR  354 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~  354 (908)
                      +++|++......+..+++++++.|+  ++.|++.+.|...............|.+.+.......++|..|+....+...+
T Consensus       263 ~~viv~~~~~~~~~~~l~~~~~~g~--~~~~i~~~~~~~~~~~~~~~~~~~~g~l~~~~~~~~~~~f~~~~~~~~~~~~~  340 (570)
T 5KZQ_A          263 ARVAVLFTRSEDARELLAASQRLNA--SFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNS  340 (570)
T ss_pred             cEEEEEECCHHHHHHHHHHHHHhCC--CeEEEEeCcccCChhHHhcchhHhceEEEEecCCCCCCcHHHHHHhcCCCCCC
Confidence            8888887776677888888888776  46788776554322110001123344444433333333444443322222223


Q NP_000836.2     355 RNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM  434 (908)
Q Consensus       355 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~  434 (908)
                      .+.++.++|++.+.|....        ..|+.. ..... ......++.++||||+++++|++++....+......|...
T Consensus       341 ~~~~~~~~~~~~~~c~~~~--------~~c~~~-~~~~~-~~~~~~~~~~~ydAv~~~a~al~~~~~~~~~~~~~~c~~~  410 (570)
T 5KZQ_A          341 RNPWFREFWEQRFRCSFRQ--------RDCAAH-SLRAV-PFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAM  410 (570)
T ss_pred             CCHHHHHHHHHHcCCCCCC--------CCCCCC-CcccC-CCCCCcchHHHHHHHHHHHHHHHHHHhccCCCCCCCcccc
Confidence            4556777777666553210        011110 00000 0112345678999999999999998764332211223221


Q NP_000836.2     435 STIDGKEL-LGYIRAVNFNG------SAGTPVTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQLHLKVEDMQWAH  506 (908)
Q Consensus       435 ~~~~~~~l-~~~l~~~~f~G------~~G~~v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~~~~~~~i~w~~  506 (908)
                      ...++.++ .+.+++..|.+      .+| .+.||++|++...|.|++++..+ +...++.||.|+....++...+.|++
T Consensus       411 ~~~~~~~l~~~~l~~~~f~~~~~~~~~~g-~v~fd~~G~~~~~y~i~~~~~~~~~~~~~~~vg~~~~~~~~~~~~i~W~~  489 (570)
T 5KZQ_A          411 RPVNGRRLYKDFVLNVKFDAPFRPADTHN-EVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWAS  489 (570)
T ss_pred             CcCChhHHHHhhhhceeecCCCCCCCCCC-EEEeCCCCCCCccEEEEEEEEcCCCCeeEEEEEEECCCCccccccccCCC
Confidence            11234443 35577777763      566 89999999998889998887432 12368899999865444434678976


Q NP_000836.2     507 RE-HTHPASVCSLPCKPGERKKTVKGVPCCWHCERCEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWH  580 (908)
Q Consensus       507 ~~-~~~p~s~Cs~~c~~G~~k~~~~~~~Cc~~c~~C~~~~~~~~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s  580 (908)
                      +. .+.|.++|++.|++|+++...+++.|||+|.+|++|+++++.++|.+||.++|||++++.|.+++..|+.+.
T Consensus       490 ~~~~~~~~s~C~~~C~~g~~~~~~~~~~CC~~C~~C~~g~~~~~~~~C~~Cp~~~~~n~~~~~C~~~~~~~l~~~  564 (570)
T 5KZQ_A          490 PSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIREG  564 (570)
T ss_pred             CCCCCCCceeecCCCCCCceeCCCCCCccccccccCCCCeeecCccccccCCCccccCCCCCCeEecceehhccC
Confidence            42 345889999999999998766567899999999999999988999999999999999999999888887664


No 15
>5K5T_A Extracellular calcium-sensing receptor; Venus Flytrap module, cysteine rich; HET: NAG, SO4; 3.1A {Homo sapiens}
Probab=100.00  E-value=2.4e-42  Score=400.86  Aligned_cols=534  Identities=32%  Similarity=0.559  Sum_probs=355.1  Template_Neff=11.000

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGER----------GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSR  108 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~----------~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~  108 (908)
                      ....+++++||+++|.++....          ...|+.. ...+.....|+++|++++|+++++++|+++++.+.|++++
T Consensus        25 ~~~~~~~i~Ig~l~p~~~~~~~~~~~~~~~~~~~~c~~~-~~~~~~~~~a~~~Av~~iN~~~~llp~~~l~~~~~D~~~~  103 (615)
T 5K5T_A           25 RAQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRY-NFRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNT  103 (615)
T ss_dssp             CEEECCSEEEEEEECSBSCBCCCCCCCSSCCCCCCBCSB-CHHHHHHHHHHHHHHHHHHHCSSSSTTCCEEEEEEECTTC
T ss_pred             ceEecCCEEEEeeeeeeecccCCCCCcccCCCcccceee-ccccHHHHHHHHHHHHHHhcCCCCCCCCceeEEEEcCCCC
Confidence            4567789999999999864321          1234321 1245678899999999999998888999999999999887


Q NP_000836.2     109 DTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTR  188 (908)
Q Consensus       109 ~~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~  188 (908)
                      ...+.+.+.+++...    .....+....+.+.....++.++||+.++..+..++.++..+++|+|++.+.++.++++..
T Consensus       104 ~~~a~~~~~~l~~~~----~~~~~~~~~~~~~~~~~~~v~~viG~~~s~~~~~~a~~~~~~~ip~is~~~~~~~l~~~~~  179 (615)
T 5K5T_A          104 VSKALEATLSFVAQN----KIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQ  179 (615)
T ss_dssp             HHHHHHHHHHHHCCC----CCHHHSGGGGCC-----CCEEEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTT
T ss_pred             HHHHHHHHHHHHhcC----CccCCCccccccCCCCCCCeEEEEcCCChHHHHHHHHHhcccCCCeEeccccCcccCCccc
Confidence            655444444443210    0000000000011111135678999988877778888999999999999887777766556


Q NP_000836.2     189 YDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKR  268 (908)
Q Consensus       189 ~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~  268 (908)
                      +++++++.|++..++.++++++++++|++|++++.+++++....+.|++.+++. ++++.....+....+..++...+++
T Consensus       180 ~~~~~~~~p~~~~~~~al~~~l~~~~w~~v~vl~~~~~~g~~~~~~~~~~~~~~-gi~v~~~~~~~~~~~~~~~~~~~~~  258 (615)
T 5K5T_A          180 FKSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEER-DICIDFSELISQYSDEEEIQHVVEV  258 (615)
T ss_dssp             CTTEEESSCCTTHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHT-TCEEEEEEEECTTCCHHHHHHHHHH
T ss_pred             CCcccccCCChHHHHHHHHHHHHHcCCcEEEEEEecCcccchHHHHHHHHHHHC-CcEEEEEEeecCCCCHHHHHHHHHH
Confidence            899999999999999999999999999999999988888888888888888775 4776544333211122345556666


Q NP_000836.2     269 LLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPV-YQQEEIAEGAVTILPKRASIDGFDRYFRS  347 (908)
Q Consensus       269 l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~-~~~~~~~~g~~~~~~~~~~~~~~~~~~~~  347 (908)
                      ++. .++++|++......+..+++++.+.++.+ ..|+..+.|....... ........|.+.+.......++|..|+..
T Consensus       259 i~~-~~~~viv~~~~~~~~~~~l~~~~~~~~~~-~~~i~~~~~~~~~~~~~~~~~~~~~g~l~~~~~~~~~~~f~~f~~~  336 (615)
T 5K5T_A          259 IQN-STAKVIVVFSSGPDLEPLIKEIVRRNITG-KIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKK  336 (615)
T ss_dssp             HHH-CCCCEEEEECCHHHHHHHHHHHHHHTCCC-CEEEECHHHHTCTTTCCGGGHHHHTTCEEEEECCBCCTTHHHHHHT
T ss_pred             HHh-CCCeEEEEeCCchhHHHHHHHHHHcCCCC-CEEEEehhHhcchhccCccccceeceEEEEEeccccCccHHHHHHH
Confidence            663 57899988877777888888888888753 5788777665432110 00112344555555444445566666544


Q NP_000836.2     348 RTLANNRRNVWFAEFWEENFGCKLGSHGKR----------------------NSHIKKCTGLERIARD----SSYEQEGK  401 (908)
Q Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------------------~~~~~~c~~~~~~~~~----~~~~~~~~  401 (908)
                      ..+.....+.++.++|+..+.|........                      ..+...|++.+.+...    .......+
T Consensus       337 l~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~C~~~~~~~~~~~~~~~~~~~~~  416 (615)
T 5K5T_A          337 VHPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSQSSTAFRPLCTGDENINSVETPYIDYTHLRI  416 (615)
T ss_dssp             CCTTTCSSBTHHHHHHHHHHTSEECSSCCSCCCSCTTGGGGGSTTCCSSSGGGTCCCEECSCCCTTTSCCTTTCCSCBSH
T ss_pred             hCcccCCCChHHHHHHHHHhCCcCCCCCCCCCCchhhccCCcccCCcccCCCCCCCCCCCCCCCcccCCCCccccccccc
Confidence            332223344566777777666542210000                      0011123322211100    00112345


Q NP_000836.2     402 VQFVIDAVYSMAYALHNMHKDLCPG---YIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQI  478 (908)
Q Consensus       402 ~~~~yDAv~~la~Al~~~~~~~~~~---~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~  478 (908)
                      +.++||||+++|+||+++..+.+..   ....|.......++.+.+.|++.+|.|.+|+.|.||++|++...|.|++++.
T Consensus       417 ~~~~ydAV~~~A~aL~~~~~~~~~~~~~~~~~c~~~~~~~~~~l~~~l~~~~f~g~~G~~v~fd~~Gd~~~~y~I~~~~~  496 (615)
T 5K5T_A          417 SYNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHL  496 (615)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHCCTTSBTBTTBBCCCSTTCCHHHHHHHHHSCEEECTTSCEEEBCSSSBBCCEEEEEEEEE
T ss_pred             hhHHHHHHHHHHHHHHHHHhcCCCCCCCCCCCCccccccCHHHHHHHHhhCeEECCCCCEEEeCCCCCCCceEEEEEEEe
Confidence            6789999999999999987654321   0122222112334557788888899988776799999999988999999874


Q NP_000836.2     479 TN--KSTEYKVIGHWTNQL------HLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKG-VPCCWHCERCEGYNYQV-  548 (908)
Q Consensus       479 ~~--~~~~~~~Vg~~~~~~------~~~~~~i~w~~~~~~~p~s~Cs~~c~~G~~k~~~~~-~~Cc~~c~~C~~~~~~~-  548 (908)
                      ..  +...++.||.|+...      .++...+.|.++...+|.++|+.+|++|+++...++ +.|||+|.+|+++++++ 
T Consensus       497 ~~~~~~~~~~~Vg~~~~~~~~~~~l~~~~~~i~W~~~~~~~P~s~Cs~~C~~G~~~~~~~~~~~Cc~~C~~C~~~~~s~~  576 (615)
T 5K5T_A          497 SPEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGFSREVPFSNCSRDCLAGTRKGIIEGEPTCCFECVECPDGEYSDE  576 (615)
T ss_dssp             CTTTCSEEEEEEEEEESSSCTTSSEEECGGGCCBTTTBCSCCCCCSSCCCCTTEEEEECSSSCTTCEEEEECCTTEECCS
T ss_pred             CCCCCCEEEEEEEEEEeecCCCCeEEEeccceecCCCCCCCCeeeecCCCCcCceecccCCCCcccceeeeCCCCcEECC
Confidence            31  123588999998542      123335789764446699999999999999877666 68999999999999997 


Q NP_000836.2     549 -DELSCELCPLDQRPNMNRTGCQLIPIIKLEWH  580 (908)
Q Consensus       549 -~~~~C~~cp~~~~~~~~~~~c~~~~~~~~~~s  580 (908)
                       +.++|.+||.++|||++++.|.+++..|+.|+
T Consensus       577 ~~~~~C~~Cp~~~~~n~~~t~C~~~~~~~l~~~  609 (615)
T 5K5T_A          577 TDASACNKCPDDFWSNENHTSCIAKEIEFLSDY  609 (615)
T ss_dssp             SSCSSCEECCTTEEECTTSSSEEECCC------
T ss_pred             CCcccccCCCCCceecCCCCcEEecEEEeecCC
Confidence             57999999999999999999999988888776


No 16
>6FFH_A Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate; 7TM, RECEPTOR, GPCR, MEMBRANE-PROTEIN, SIGNALING; HET: D7W, OLC, YCM, MES, OLA; 2.65A {Homo sapiens}
Probab=100.00  E-value=9.6e-38  Score=308.98  Aligned_cols=266  Identities=48%  Similarity=0.851  Sum_probs=223.2  Template_Neff=4.100

Q NP_000836.2     573 PIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRR  652 (908)
Q Consensus       573 ~~~~~~~s~~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~~~~C~~~~  652 (908)
                      +.++..+++++.+++.+++++|++++++++++++++|+++++|.+++.+++++|+|+.++|+++++++..|+...|.+|.
T Consensus         4 PveyLs~S~~~~i~llaLSaIGILitLiiLIIfI~~RsTPvIk~ssp~L~~~iLLG~~l~~~~~~~~~~~p~~~~C~lR~   83 (444)
T 6FFH_A            4 PVQYLRWGDPAPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFXLIAKPKQIYCYLQR   83 (444)
T ss_dssp             HHHHHHTTCCHHHHHHHHHHHHHHHHHHHHHHHHHTTTSHHHHHSCHHHHHHHHHHHHHHHHTHHHHBSCSCHHHHHHHH
T ss_pred             cceeccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCchhhcCCHHHHHHHHHHHHHHHHHHHHhccCCchhHHHHHH
Confidence            45677889999999999999999999999999999999999999999999999999999999999999999999999999


Q NP_000836.2     653 VFLGLGMCFSYAALLTKTNRIHRIFEQGKKSV---------TAP------------------------------------  687 (908)
Q Consensus       653 ~~~~~gf~l~~~~l~~K~~ri~~if~~~~~~~---------~~~------------------------------------  687 (908)
                      |++++||+++||++++|+||++++|..++++.         .++                                    
T Consensus        84 ~~l~lgfsl~~~~l~vKt~RI~~if~~~~~~~~~~~~~~~~~~~~~i~d~~l~~~v~~~~l~~~~~~~~~~~~~~d~~~~  163 (444)
T 6FFH_A           84 IGIGLSPAMSYSALVTKTYRAARILAMSKKNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIG  163 (444)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHTCCEEEEEECTTSCEEEETTEEEESSSCHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHhccccChhhhhhcccccceeeecCcchhhhhhhhHHhcCCcccchhhhhhhhhcc
Confidence            99999999999999999999999998664320         000                                    


Q NP_000836.2     688 --------------------------------------------------------------------------------  687 (908)
Q Consensus       688 --------------------------------------------------------------------------------  687 (908)
                                                                                                      
T Consensus       164 ~~~~~~~~~~~~~~~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  243 (444)
T 6FFH_A          164 RNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAV  243 (444)
T ss_dssp             SCCTTBCCHHHHHHHHHHHHHHHHHHHHTCTTTHHHHHHSCHHHHHHHHHHHHHHCHHHHTTCHHHHHHHHTTCHHHHHH
T ss_pred             cCCCCccchhHHHHHhcCchhHHHHHhHhccCCCccccchhHHHHHHHHHhhhccCcccccccchhHHHHHHhchhHHHH
Confidence                                                                                            


Q NP_000836.2     688 -------------------------------------KFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRT  730 (908)
Q Consensus       688 -------------------------------------~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~  730 (908)
                                                           ++.+.+.++.++++++.+|+++++.|...+|+........   
T Consensus       244 ~~~~~~w~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~iq~~i~~~~~~~~pp~~~~~~~~---  320 (444)
T 6FFH_A          244 NLAKSRWYNQTPNRAKRVITTFRTGTWDAYKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPS---  320 (444)
T ss_dssp             HHTTSHHHHHSHHHHHHHHHHHHHSSSTTSCC--------CHHHHHHHHHHHHHHHHHHHHHHHHHSCCCBSSSCC----
T ss_pred             hhhhcccccCCCCccceeeeeeecCCccchhhccCCcccCCHHHHHHHHHHHHHHHHHHHHHHHhcCCCCCccCCcc---
Confidence                                                 0112233455566677899999999999998876543211   


Q NP_000836.2     731 LDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEK  810 (908)
Q Consensus       731 ~~~~~~~~~~~C~~~~~~~~~~~~~~~~ll~~~~~la~~~R~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~  810 (908)
                          .......|...+.++++.++|+++|+++|+++|+++|++|++|||+|+|++++|+.+++|+++.|+++.....   
T Consensus       321 ----~~~~~~~C~~~~~~~~~~l~y~~iLll~~~~~A~~tR~vp~~fnEak~I~~~~y~~~ii~~~~~p~~~~~~~~---  393 (444)
T 6FFH_A          321 ----IREVYLICNTTNLGVVAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYK---  393 (444)
T ss_dssp             ------CCBCCBCCCHHHHHHHHHHHHHHHHHHHHHHHHTTTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCSCH---
T ss_pred             ----cceEEEeecCCChHHHHHHHHHHHHHHHHHHHHHHhcCCchhhhHHHHHHHHHHHHHHHHHHHHHHHHcCCcH---
Confidence                2345679998777778899999999999999999999999999999999999999999999999998876533   


Q NP_000836.2     811 MYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKR  852 (908)
Q Consensus       811 ~~~~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~  852 (908)
                          +.+.++++++++++.++++|+||+|.++++||++.+..
T Consensus       394 ----~~~~~~~i~l~~t~~l~~iF~PK~~~I~~~p~~n~~~~  431 (444)
T 6FFH_A          394 ----IITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSA  431 (444)
T ss_dssp             ----HHHHHHHHHHHHHHHHHHHTHHHHHHHHHCTTTC----
T ss_pred             ----HHHHHHHHHHHHHHHHHHHHHHHHHHHHcCcccchHHH
Confidence                23677899999999999999999999999999887653


No 17
>6FFI_A Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate; 7TM, RECEPTOR, GPCR, MEMBRANE-PROTEIN, SIGNALING; HET: YCM, MES, OLA, D8B; 2.2A {Homo sapiens}
Probab=100.00  E-value=9.6e-38  Score=308.98  Aligned_cols=266  Identities=48%  Similarity=0.851  Sum_probs=222.1  Template_Neff=4.100

Q NP_000836.2     573 PIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRR  652 (908)
Q Consensus       573 ~~~~~~~s~~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~~~~C~~~~  652 (908)
                      +.++..+++++.+++.+++++|++++++++++++++|+++++|.+++.+++++|+|+.++|+++++++..|+...|.+|.
T Consensus         4 PveyLs~S~~~~i~llaLSaIGILitLiiLIIfI~~RsTPvIk~ssp~L~~~iLLG~~l~~~~~~~~~~~p~~~~C~lR~   83 (444)
T 6FFI_A            4 PVQYLRWGDPAPIAAVVFACLGLLATLFVTVVFIIYRDTPVVKSSSRELCYIILAGICLGYLCTFXLIAKPKQIYCYLQR   83 (444)
T ss_dssp             HHHHHHTTCCHHHHHHHHHHHHHHHHHHHHHHHHHGGGSHHHHSSCHHHHHHHHHHHHHHHHTHHHHBCCSCHHHHHHHH
T ss_pred             cceeccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCchhhcCCHHHHHHHHHHHHHHHHHHHHhccCCchhHHHHHH
Confidence            45677889999999999999999999999999999999999999999999999999999999999999999999999999


Q NP_000836.2     653 VFLGLGMCFSYAALLTKTNRIHRIFEQGKKSV---------TAP------------------------------------  687 (908)
Q Consensus       653 ~~~~~gf~l~~~~l~~K~~ri~~if~~~~~~~---------~~~------------------------------------  687 (908)
                      |++++||+++||++++|+||++++|..++++.         .++                                    
T Consensus        84 ~~l~lgfsl~~~~l~vKt~RI~~if~~~~~~~~~~~~~~~~~~~~~i~d~~l~~~v~~~~l~~~~~~~~~~~~~~d~~~~  163 (444)
T 6FFI_A           84 IGIGLSPAMSYSALVTKTYRAARILAMSKKNIFEMLRIDEGLRLKIYKDTEGYYTIGIGHLLTKSPSLNAAKSELDKAIG  163 (444)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCEEEEEECTTCCEEEETTEECCCSSCHHHHHHHHHHHHS
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHhccccChhhhhhcccccceeeecCcchhhhhhhhHHhcCCcccchhhhhhhhhcc
Confidence            99999999999999999999999998664320         000                                    


Q NP_000836.2     688 --------------------------------------------------------------------------------  687 (908)
Q Consensus       688 --------------------------------------------------------------------------------  687 (908)
                                                                                                      
T Consensus       164 ~~~~~~~~~~~~~~~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  243 (444)
T 6FFI_A          164 RNTNGVITKDEAEKLFNQDVDAAVRGILRNAKLKPVYDSLDAVRRAALINMVFQMGETGVAGFTNSLRMLQQKRWDEAAV  243 (444)
T ss_dssp             SCCTTBCCHHHHHHHHHHHHHHHHHHHHTCTTTHHHHHHSCHHHHHHHHHHHHHHHHHHHTTCHHHHHHHHTTCHHHHHH
T ss_pred             cCCCCccchhHHHHHhcCchhHHHHHhHhccCCCccccchhHHHHHHHHHhhhccCcccccccchhHHHHHHhchhHHHH
Confidence                                                                                            


Q NP_000836.2     688 -------------------------------------KFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGEQRT  730 (908)
Q Consensus       688 -------------------------------------~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~~~~  730 (908)
                                                           ++.+.+.++.++++++.+|+++++.|...+|+........   
T Consensus       244 ~~~~~~w~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~iq~~i~~~~~~~~pp~~~~~~~~---  320 (444)
T 6FFI_A          244 NLAKSRWYNQTPNRAKRVITTFRTGTWDAYKICTKKPRFMSACAQLVIAFILICIQLGIIVALFIMEPPDIMHDYPS---  320 (444)
T ss_dssp             HHTTSHHHHHSHHHHHHHHHHHHHSSSTTSCC--------CHHHHHHHHHHHHHHHHHHHHHHHHHSCCCBC--------
T ss_pred             hhhhcccccCCCCccceeeeeeecCCccchhhccCCcccCCHHHHHHHHHHHHHHHHHHHHHHHhcCCCCCccCCcc---
Confidence                                                 0112233455566677899999999999998876543211   


Q NP_000836.2     731 LDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQSAEK  810 (908)
Q Consensus       731 ~~~~~~~~~~~C~~~~~~~~~~~~~~~~ll~~~~~la~~~R~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~  810 (908)
                          .......|...+.++++.++|+++|+++|+++|+++|++|++|||+|+|++++|+.+++|+++.|+++.....   
T Consensus       321 ----~~~~~~~C~~~~~~~~~~l~y~~iLll~~~~~A~~tR~vp~~fnEak~I~~~~y~~~ii~~~~~p~~~~~~~~---  393 (444)
T 6FFI_A          321 ----IREVYLICNTTNLGVVAPLGYNGLLILACTFYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYK---  393 (444)
T ss_dssp             ------CCBCCBCCCHHHHHHHHHHHHHHHHHHHHHHHHTTTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCSCH---
T ss_pred             ----cceEEEeecCCChHHHHHHHHHHHHHHHHHHHHHHhcCCchhhhHHHHHHHHHHHHHHHHHHHHHHHHcCCcH---
Confidence                2345679998777778899999999999999999999999999999999999999999999999998876533   


Q NP_000836.2     811 MYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKR  852 (908)
Q Consensus       811 ~~~~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~  852 (908)
                          +.+.++++++++++.++++|+||+|.++++||++.+..
T Consensus       394 ----~~~~~~~i~l~~t~~l~~iF~PK~~~I~~~p~~n~~~~  431 (444)
T 6FFI_A          394 ----IITMCFSVSLSATVALGCMFVPKVYIILAKPERNVRSA  431 (444)
T ss_dssp             ----HHHHHHHHHHHHHHHCCCCCHHHHHHHHHCTTTC----
T ss_pred             ----HHHHHHHHHHHHHHHHHHHHHHHHHHHHcCcccchHHH
Confidence                23677899999999999999999999999999887653


No 18
>4OR2_B Chimera of Soluble cytochrome b562; Human metabotropic glutamate receptor 1; HET: PO4, OLC, OLA, CLR, FM9; 2.8A {Escherichia coli, Homo sapiens}
Probab=100.00  E-value=1.8e-37  Score=330.24  Aligned_cols=271  Identities=46%  Similarity=0.820  Sum_probs=228.1  Template_Neff=8.400

Q NP_000836.2     570 QLIPIIKLEWHSPWAVVPVFVAILGIIATTFVIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICS  649 (908)
Q Consensus       570 ~~~~~~~~~~s~~~~~~~~~~~~~~i~~~~~~~~~~~~~r~~~~i~~s~~~~~~~~l~G~~l~~~~~~~~~~~~~~~~C~  649 (908)
                      .+.+..+.+++++..+++.+++++|++++++++++++++|+++.+|+++|.++.++++|++++|++++++..+|++..|.
T Consensus       108 ~~~p~~~l~~~~~~~i~~~~l~~lgil~~l~~~~~~~~~R~~~vIk~ss~~l~~liL~G~~l~~~s~~~~~~~ps~~~C~  187 (389)
T 4OR2_B          108 YLIPVRYLEWSNIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCY  187 (389)
T ss_dssp             GTSCCBCCCTTSHHHHHHHHHHHHHHHHHHHHHHHHHHTSSSHHHHTSCHHHHHHHHHHHHHHHHHHHHHHSCCCHHHHH
T ss_pred             ccCcccccCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHcCCChhhhcCCHHHHHHHHHHHHHHHHHHHHhcCCCchhcHh
Confidence            33355677888999999999999999999988999999999999999999999999999999999999999899999999


Q NP_000836.2     650 FRRVFLGLGMCFSYAALLTKTNRIHRIFEQGKKSV--TAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPHIIIDYGE  727 (908)
Q Consensus       650 ~~~~~~~~gf~l~~~~l~~K~~ri~~if~~~~~~~--~~~~~~~~~~l~~~~~~~~~i~~~i~~~w~~~~p~~~~~~~~~  727 (908)
                      +|.|++++||+++||++++|+||++++|++++++.  +.++..+++.++..++++++++++++++|+..+|+.+......
T Consensus       188 ~r~~~~~lgf~l~~g~l~~Kt~Ri~~iF~~~~~~~~~~~~~~~~~~~~~~~~~~l~~i~~iil~~w~~~~p~~~~~~~~~  267 (389)
T 4OR2_B          188 LQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPS  267 (389)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHCCC-----CCCCCSSCSHHHHHHHHHHHHHHHHHHHHHHHHHSCCCEEEECCS
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCCCcCCCcccCCHHHHHHHHHHHHHHHHHHHHHHHhcCCCCCeecCCC
Confidence            99999999999999999999999999998765421  1234566777777788888999999999999999887543211


Q NP_000836.2     728 QRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIIWLAFIPIFFGTAQS  807 (908)
Q Consensus       728 ~~~~~~~~~~~~~~C~~~~~~~~~~~~~~~~ll~~~~~la~~~R~~~~~~nes~~i~~~~~~~~~~~~~~~~~~~~~~~~  807 (908)
                             .......|++.+.++.+.++|+++|++++++|||++|++|++|||+|+|++++|+++++|+++.|+++..+. 
T Consensus       268 -------~~~~~~~C~~~~~~~~~~~~y~~lLl~~~~~LA~~tR~~~~~~nEsk~i~~~iy~~~~~~~i~~p~~~~~~~-  339 (389)
T 4OR2_B          268 -------IKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNY-  339 (389)
T ss_dssp             -------SSCCEEEECCCSHHHHHHHHHHHHHHHHHHHHHHHTTTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSC-
T ss_pred             -------CceEEEecCCCcHHHHHHHHHHHHHHHHHHHHHHHhcCCCcccCHHHHHHHHHHHHHHHHHHHHHHHhCCCH-
Confidence                   123456899876667788999999999999999999999999999999999999999999999999875432 


Q NP_000836.2     808 AEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYIIIFHPEQNVQKRKR  854 (908)
Q Consensus       808 ~~~~~~~~~~~~~~i~~~~~~~l~~~f~PK~~~i~~~~~~~~~~~~~  854 (908)
                            .+.+.+++++++++++++++|+||++.++++|+++.+++.+
T Consensus       340 ------~~~~~~~~il~~~~~~l~~lF~PK~~~i~~~~~~~~~~~~~  380 (389)
T 4OR2_B          340 ------KIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFT  380 (389)
T ss_dssp             ------HHHHHHHHHHHHHHHHCCCCCHHHHHHHHTCHHHHC-----
T ss_pred             ------HHHHHHHHHHHHHHHHHHHHHccceeEEeeCcccchhhhhh
Confidence                  23467788899999999999999999999999998876544


No 19
>6BT5_B Metabotropic glutamate receptor 8; mGluR8, GRM8, L-AP4, GENE ID:; HET: NAG, E7P; 2.92A {Homo sapiens}
Probab=99.87  E-value=2.3e-27  Score=265.12  Aligned_cols=468  Identities=100%  Similarity=1.505  Sum_probs=271.7  Template_Neff=11.300

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...+++++||+++|+++.......|+......+.....|+++|++++|+++++++|.++++.+.|++.++..+.+.+...
T Consensus         4 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~~~~~a~~~iN~~~~~~~~~~l~~~~~d~~~~~~~~~~~~~~~   83 (479)
T 6BT5_B            4 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF   83 (479)
T ss_dssp             EEECCSEEEEEEECCEEECSSSCSEEEECCCCCCCHHHHHHHHHHHHHHCSSTTTTCCEEEEEEECTTCHHHHHHHHGGG
T ss_pred             eeeCCCEEEEEEEeccccCCCCCCCCcccccccHHHHHHHHHHHHHHhcCCCcCCCCeEeeEEecCCCCHHHHHHHHHHH
Confidence            35567899999999987543223454432235677889999999999998887778899999999877643323333444


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++++.+...+..|...........++++++||+.++..+..++.++...++|+|++.+..+.+.+...+++++++.++.
T Consensus        84 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~~~~~~  163 (479)
T 6BT5_B           84 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  163 (479)
T ss_dssp             CC------------------------CEEEEECCSSHHHHHHHHHHHTTTTCCEEESSCCCGGGGCTTTCTTEEESSCCH
T ss_pred             HHHHHhccccccccCCCCCCccCCCCceEEEEcCCCchHHHHHHHHHHHhCCCEEecCCCCcccCCcccccceeecCCCh
Confidence            44433210000000000000000013788999998887777888999999999999887666554433578899999999


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      ...+.++++++.+++|+++++++.++.++....+.+++.+++.+++++.....+.......++...++++++..++++|+
T Consensus       164 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~~~v~~~~~~~~~~~~~~~~~~~~~i~~~~~~~~iv  243 (479)
T 6BT5_B          164 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVSIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  243 (479)
T ss_dssp             HHHHHHHHHHHHHHTCCEEEEEEESSHHHHHHHHHHHHHHHHCSSCEEEEEEEECSSCCTTHHHHHHHHHTTSTTCCEEE
T ss_pred             HHHHHHHHHHHHHhCCCEEEEEEEcCcchHHHHHHHHHHHHHhCCeEEEEEEecCCCCCcchHHHHHHHHHhCCCCcEEE
Confidence            88999999999888999999999777778777888887776642244443222221112234556666665224788888


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      +......+..+++++++.|+..++.|++.+.|...............+.+.+.+.......+..++........+...++
T Consensus       244 ~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~f  323 (479)
T 6BT5_B          244 MFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  323 (479)
T ss_dssp             EECCHHHHHHHHHHHHHTTCTTTCEEEECTTTTTCSTTTTTCTTTTTTCEEEEESCCCCHHHHHHHHTCCTTTCCSCTTH
T ss_pred             EeCCHHHHHHHHHHHHHhCCCCCeEEEEeccccCCCcchhcccchhceeEEEeccccCCCcHHHHHHcCCcccCCCCHHH
Confidence            87777778889999998887534567766544322110000111223333222211111122222111100111223445


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDG  439 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~  439 (908)
                      .++|++.+++..............|+..+............++..+|||+++++.|++++....+......|......++
T Consensus       324 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDav~~l~~al~~~~~~~~~~~~~~c~~~~~~~~  403 (479)
T 6BT5_B          324 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDG  403 (479)
T ss_dssp             HHHHHHHHTCCC-----------CCCSCCCBTTTBCCCCCTTHHHHHHHHHHHHHHHHHHHHHHSSSCSSCCGGGSSCCH
T ss_pred             HHHHHHHhCCcccCCCccccccccccccchhcCCccccccccHHHHHHHHHHHHHHHHHHHHhhCCCCCCCChhhccCCH
Confidence            56666555432110000000011222211100000011234677899999999999998865432211122322122345


Q NP_000836.2     440 KELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHR  507 (908)
Q Consensus       440 ~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~~  507 (908)
                      ..+.+.|++..|.|.+|.+++||++|++...+.+++++..+....++.||.|+....+....+.|+++
T Consensus       404 ~~l~~~l~~~~f~G~tG~~~~f~~~g~~~~~~~i~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~~~  471 (479)
T 6BT5_B          404 KELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHR  471 (479)
T ss_dssp             HHHHHHHHTCEEECTTSSEEECCSSSCCCCEEEEEEEEEETTEEEEEEEEEEESSEEECGGGCCC---
T ss_pred             HHHHHHHHhCceecCCCCeeEeCCCCCCCCcEEEEEEEEeCCceeEEEEEEEecceeecHHheeeccc
Confidence            56778888889999877469999999988888888887432123578899999765554456788754


No 20
>6BSZ_A Metabotropic glutamate receptor 8; mGluR8, GRM8, glutamate, GENE ID:; HET: GGL, NAG, SO4; 2.65A {Homo sapiens}
Probab=99.86  E-value=3.3e-27  Score=263.84  Aligned_cols=468  Identities=100%  Similarity=1.503  Sum_probs=273.7  Template_Neff=11.300

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...+++++||+++|.++.......|+......+.....|+++|++++|++++++++.++++.+.|++.+...+.+.+.+.
T Consensus         4 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~~~~~a~~~iN~~~~~~~~~~l~~~~~d~~~~~~~~~~~~~~~   83 (479)
T 6BSZ_A            4 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF   83 (479)
T ss_dssp             EEECCSEEEEEEECCEEECSTTCSEEEECCCCCCCHHHHHHHHHHHHHHCSSTTTTCCEEEEEEECTTCHHHHHHHHGGG
T ss_pred             eeeCCCEEEEEeeeceecCCCCCCCCcccccccHHHHHHHHHHHHHHhcCCCcCCCceEeeEEecCCCCHHHHHHHHHHH
Confidence            34567999999999987543223455433335677889999999999998877778899999999877653323333334


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++++.+......|...........++++++||+.++.....++.++...++|+|++.+..+.+.+...+++++++.++.
T Consensus        84 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~~~~~~  163 (479)
T 6BSZ_A           84 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  163 (479)
T ss_dssp             CCC-----------------------CEEEEECCSSHHHHHHHHHHHTTTTCCEEESSCCCGGGGCTTTCTTEEESSCCH
T ss_pred             HHHHHhccccccccCCCCCCccCCCCceEEEEcCCCchHHHHHHHHHHHhCCCeEecCCCCccccCcccccceeecCCCh
Confidence            44333210000000000000000013788999998887777888899999999999887666554434578899999999


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      ...+.++++++++++|+++++++.++.++....+.+.+.+++.+++++.....+....+..++...++++++..++++|+
T Consensus       164 ~~~~~a~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~~~~~v~~~~~~~~~~~~~~~~~~~~~i~~~~~~~~iv  243 (479)
T 6BSZ_A          164 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVSIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  243 (479)
T ss_dssp             HHHHHHHHHHHHHHTCCEEEEEEESSHHHHHHHHHHHHHHHHSSSCEEEEEEEECSSCCTTHHHHHHHHHTTSTTCCEEE
T ss_pred             HHHHHHHHHHHHHhCCCEEEEEEecCcccHHHHHHHHHHHHHhCCeEEEEEEecCCCCCcchHHHHHHHHHhCCCCcEEE
Confidence            98999999999889999999999877778878888887776542244443222211112234556666665224788888


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      +......+..+++++.+.++.+++.|+..+.|...............+.+.+.+.......+..++........+...++
T Consensus       244 ~~~~~~~~~~~l~~~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  323 (479)
T 6BSZ_A          244 MFANEDDIRRILEAAKKLQQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  323 (479)
T ss_dssp             EECCHHHHHHHHHHHHHTTCTTTCEEEECTTTTTCSTTTTTCTTTTTTCEEEEESCCCCHHHHHHHHTCCTTTCCSCTTH
T ss_pred             EeCCHHHHHHHHHHHHHhccCCCeEEEEeccccCCccchhcccchheeeEEEeccccCCCcHHHHHHcCCcccCCCCHHH
Confidence            87776778888999888876534667766544322110000111223333322221111122211111000011223345


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDG  439 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~  439 (908)
                      .++|++.+++..............|...+............++..+|||+++++.|+++.....+......|......++
T Consensus       324 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDav~~~~~al~~~~~~~~~~~~~~c~~~~~~~~  403 (479)
T 6BSZ_A          324 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDG  403 (479)
T ss_dssp             HHHHHHHHTCCC-----------CCCSCCCTTTTSCCCCCTTHHHHHHHHHHHHHHHHHHHHHHSSSCSSCCGGGSSCCH
T ss_pred             HHHHHHHhCCcccCCCCcccccccccCcccccCCccccccccHHHHHHHHHHHHHHHHHHHHhhCCCCCCCCchhccCCH
Confidence            56666554432110000000011122111000000011234677899999999999998865432211122322122345


Q NP_000836.2     440 KELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHR  507 (908)
Q Consensus       440 ~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~~  507 (908)
                      ..+.+.|++.+|.|.+|+.+.||++|++...+.+++++..+....+..||.|+....++...+.|+++
T Consensus       404 ~~l~~~l~~~~f~G~tG~~v~fd~~g~~~~~~~i~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~~~  471 (479)
T 6BSZ_A          404 KELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAHR  471 (479)
T ss_dssp             HHHHHHHHHCCEECTTSCEECCCTTSCCCCEEEEEEEEECSSCEEEEEEEEEESSEEECGGGCCCCCC
T ss_pred             HHHHHHHHhCceecCCCCceEeCCCCCCCCcEEEEEEEEeCCceeeEEEEEEecceeeeHhhceeccc
Confidence            56778888889999877469999999988788888887422123578899999765555556888764


No 21
>3KS9_B Metabotropic glutamate receptor 1; Glutamate Receptors, mGluR1, Dimerization, Glutamic; HET: Z99, NAG; 1.9A {Homo sapiens}
Probab=99.85  E-value=1.4e-26  Score=259.76  Aligned_cols=465  Identities=41%  Similarity=0.750  Sum_probs=274.0  Template_Neff=11.100

Q NP_000836.2      37 AHSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYA  112 (908)
Q Consensus        37 ~~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a  112 (908)
                      ......+++++||+++|.++...    ....|+......+.....|+++|++++|+++++++|+++++.+.|+++++..+
T Consensus         9 ~~~~~~~~~~~Ig~l~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~a~~~in~~~~~~~~~~i~~~~~d~~~~~~~~   88 (496)
T 3KS9_B            9 RSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVA   88 (496)
T ss_dssp             CCCEEECCSEEEEEEECSBCCCCGGGGGGTCCCCBCCCCCCHHHHHHHHHHHHHHHCSSSSTTCCEEEEEEECTTCHHHH
T ss_pred             cceEEecCCEEEEEEEEeccCCCCCCCCCCCCccccccccHHHHHHHHHHHHHHhcCCCCCCCceEeeEEEeCCCCHHHH
Confidence            34456778999999999987531    12356543334567788999999999999877777899999999988876544


Q NP_000836.2     113 LEQSLTFVQALIE----KDASDVKCANGDP--PIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN  186 (908)
Q Consensus       113 ~~~~~~~~~~l~~----~~~~~~~~~~~~~--~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~  186 (908)
                      .+.+.+++.....    +......|...+.  .....+++++++||+.++.....++.++...++|+|++.+..+.+.+.
T Consensus        89 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~  168 (496)
T 3KS9_B           89 LEQSIEFIRDSLISIRDEKDGINRCLPDGQSLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDK  168 (496)
T ss_dssp             HHHHHHHHHTTC--------------------------CCEEEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCT
T ss_pred             HHHHHHHHHHccccccCCCCcccccCCCCCCCCCCCCCCCeEEEEcCCCcHHHHHHHHHHHHhCCCEEEeccCchhcCCc
Confidence            4443333321000    0000000000000  000001578899998887777778888999999999988766655443


Q NP_000836.2     187 TRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKII  266 (908)
Q Consensus       187 ~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~  266 (908)
                      ..+++++++.++....+.++++++++++|+++++++.++.++....+.+++.+++. ++++.....+.......++...+
T Consensus       169 ~~~~~~~~~~~~~~~~~~a~~~~l~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~l  247 (496)
T 3KS9_B          169 TLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQE-GLSIAHSDKIYSNAGEKSFDRLL  247 (496)
T ss_dssp             TTCTTEEESSCCTHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHTTT-TCEEEEEEEECTTCCHHHHHHHH
T ss_pred             cccCcceecCCCHHHHHHHHHHHHHHcCCCEEEEEEeCCcchhHHHHHHHHHHHHc-CCeEEEEEEecccCChhHHHHHH
Confidence            34688999999999999999999988899999999987777877778888877765 35554322121111234556667


Q NP_000836.2     267 KRLLETP--NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRY  344 (908)
Q Consensus       267 ~~l~~~~--~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~  344 (908)
                      ++++. .  +.++|++......+..+++++++.|+..++.|++.+.|...............+.+.+.........+..+
T Consensus       248 ~~l~~-~~~~~~~iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~  326 (496)
T 3KS9_B          248 RKLRE-RLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDY  326 (496)
T ss_dssp             HHHHH-TTTTCCEEEEECCHHHHHHHHHHHHHHTCCSCCEEEECTTTTTCHHHHTTCHHHHTTCEEEEECCCCCHHHHHH
T ss_pred             HHHHH-hCCCCeEEEEEcCHHHHHHHHHHHHHcCCCCceEEEeeccccCCchhhccccchhcceEEEEecCCCCcCHHHH
Confidence            77653 3  55788777666677788888888887544567766544332110000111122333322222222223222


Q NP_000836.2     345 FRSRTLANNRRNVWFAEFWEENFGCKLGSHGK-RNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDL  423 (908)
Q Consensus       345 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~  423 (908)
                      +........+...++.++|++.+.+....... ...+...|.+++....  ......+++++|||++++++|++++....
T Consensus       327 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~ydav~~~a~al~~~~~~~  404 (496)
T 3KS9_B          327 FLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRICTGNESLEE--NYVQDSKMGFVINAIYAMAHGLQNMHHAL  404 (496)
T ss_dssp             HTTCCTTTCCSCTTHHHHHHHHTTCBCC-------CCSSBCCSCCCTTT--TCCCCTTHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHhCCCCCCCCCCcHHHHHHHHcCccCCcccCCCCCcCccCCCCccccc--cccccchHHHHHHHHHHHHHHHHHHHHHh
Confidence            21111111122345666666655542110000 0001112322111100  01234567789999999999999887543


Q NP_000836.2     424 CPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTP-VTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVE  500 (908)
Q Consensus       424 ~~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~-v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~  500 (908)
                      +......|......++..+.+.|++..|.|.+| . ++||++|++...+.|++++..+ +...++.||.|+... .++..
T Consensus       405 ~~~~~~~c~~~~~~~~~~l~~~l~~~~f~g~tG-~~v~fd~~G~~~~~~~i~~~~~~~~~~~~~~~vg~~~~~~l~~~~~  483 (496)
T 3KS9_B          405 CPGHVGLCDAMKPIDGSKLLDFLIKSSFIGVSG-EEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDY  483 (496)
T ss_dssp             STTCSSCCGGGSSCCHHHHHHHHHTCEEECTTS-CEEECCTTSCCCCEEEEEEEEECSSSCEEEEEEEEEETTEEEECC-
T ss_pred             CCCCCCCchhcCCCCHHHHHHHHhcCceecCCC-CEEEeCCCCCCCCeEEEEEEEeCCCCceEEEEEEEEECCEEEEccc
Confidence            322112232222245667888898889999988 7 9999999998888888887432 123689999999762 33334


Q NP_000836.2     501 DMQWAH  506 (908)
Q Consensus       501 ~i~w~~  506 (908)
                      .+.|++
T Consensus       484 ~i~w~~  489 (496)
T 3KS9_B          484 KIQMNK  489 (496)
T ss_dssp             ------
T ss_pred             eeeecC
Confidence            677865


No 22
>4XAR_A Metabotropic glutamate receptor 3; mGluR2 mGluR3 ECD, SIGNALING PROTEIN; HET: 40F; 2.26A {Homo sapiens}
Probab=99.85  E-value=1.6e-26  Score=260.59  Aligned_cols=462  Identities=47%  Similarity=0.846  Sum_probs=277.1  Template_Neff=10.800

Q NP_000836.2      37 AHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQS  116 (908)
Q Consensus        37 ~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~  116 (908)
                      ......+++++||+++|.++.......|+......+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+
T Consensus        32 ~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~~~~~A~~~iN~~~~~~~g~~l~l~~~d~~~~~~~a~~~~  111 (517)
T 4XAR_A           32 RREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQS  111 (517)
T ss_dssp             CCCEEECCSEEEEEEECCEEECSTTCSEEEECCCCCCHHHHHHHHHHHHHTTCSSSSTTCCEEEEEEECTTCHHHHHHHH
T ss_pred             hcceeecCCEEEEEEeeceecCCCCCCCccccccccHHHHHHHHHHHHHHhcCCCCCCCCeEeEEEEeCCCCHHHHHHHH
Confidence            34456688999999999987543233454332235677889999999999998888888999999999887755444333


Q NP_000836.2     117 LTFVQALIEK-DASDVKCANGDPPIF-TKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSR  194 (908)
Q Consensus       117 ~~~~~~l~~~-~~~~~~~~~~~~~~~-~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~  194 (908)
                      .+++.+.... +.....|........ ....++++++|+.++.....++.++...++|+|++.+..+.+.+...++++++
T Consensus       112 ~~l~~~~~~~~~~~~~~c~~~~~~~~~~~~~~v~~iig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~  191 (517)
T 4XAR_A          112 LEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFAR  191 (517)
T ss_dssp             GGGTGGGC----------------------CCCSEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTTCTTEEE
T ss_pred             HHHHHhcccccchhhhcCCCCChhhhcCCCcceEEEEcCCCcHHHHHHHHHHHHhCCCeeecccCCcccCCccccCceee
Confidence            3333210000 000000000000000 00025788999888877778888899999999998876665554445789999


Q NP_000836.2     195 VVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       195 ~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      +.|+....+.++++++.+++|++++++++++.++....+.+++.+++. ++++.....++......++...+++++...+
T Consensus       192 ~~p~~~~~~~al~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~l~~i~~~~~  270 (517)
T 4XAR_A          192 TVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLR-NISIATAEKVGRSNIRKSYDSVIRELLQKPN  270 (517)
T ss_dssp             SSCCHHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEECSSTTCCCHHHHHHHHHTCTT
T ss_pred             eCCCcHHHHHHHHHHHHHcCCcEEEEEEecCcchHHHHHHHHHHHHHC-CCEEEEEEecCcccccccHHHHHHHHHcCCC
Confidence            999999999999999988999999999987778888888888887765 3555433222211122345556666631247


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNR  354 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~  354 (908)
                      +|+|++......+..+++++++.|+  ++.|++.+.|...............+.+.+.........+..++....+....
T Consensus       271 ~~~vvl~~~~~~~~~~l~~~~~~g~--~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~  348 (517)
T 4XAR_A          271 ARVVVLFMRSDDSRELIAAASRANA--SFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNH  348 (517)
T ss_dssp             CCEEEEECCHHHHHHHHHHHHHTTC--CCEEEECTTTTTCHHHHTTCTTTSTTCEEEEECCCCCHHHHHHHHTCCTTTCC
T ss_pred             ceEEEEECChHHHHHHHHHHHHcCC--CEEEEEecchhccchhhcCCcceecceEEEEEcccCCccHHHHHHhCCCCCCC
Confidence            8888887777778889998888876  35677665544321110001122333333322222222333332221111122


Q NP_000836.2     355 RNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM  434 (908)
Q Consensus       355 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~  434 (908)
                      ...++.++|++.+.+.....   ......|...+.... .......++.++|||++++++|++++....+......|...
T Consensus       349 ~~~~~~~~~~~~~~~~~~~~---~~~~~~~~~~~~~~~-~~~~~~~~~~~~ydav~~~a~al~~~~~~~~~~~~~~c~~~  424 (517)
T 4XAR_A          349 RNPWFRDFWEQKFQCSLQNK---RNHRRVCDKHLAIDS-SNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAM  424 (517)
T ss_dssp             SCTTHHHHHHHHTTSBC----------CBCCTTCCCCT-TTCCCCTTHHHHHHHHHHHHHHHHHHHHHHCTTCSSCCGGG
T ss_pred             CChHHHHHHHHHcCCccCCc---ccCCcccccccccCC-CccccccchhHHHHHHHHHHHHHHHHHHhhCCCCCCcchhh
Confidence            33456666666554421100   000011211110000 00123456788999999999999998764432211223211


Q NP_000836.2     435 ST-IDGKELLGYIRAVNFNG-------SAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAH  506 (908)
Q Consensus       435 ~~-~~~~~l~~~l~~~~f~G-------~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~  506 (908)
                      .. ..+..+.+.+++..|.|       .+| ++.||.+|++...+.|++++..++...++.||.|+....++...+.|++
T Consensus       425 ~~~~~~~~l~~~l~~~~f~g~~~~~~~~tG-~v~fd~~G~r~~~~~i~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~~  503 (517)
T 4XAR_A          425 KILDGKKLYKDYLLKINFTAPFNPNKDADS-IVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSR  503 (517)
T ss_dssp             SSCCHHHCCCCCCSCEEECCC-----CCCC-EEECCTTSCCCCEEEEEEEEESSSCEEEEEEEEEESSEEECGGGCCCSC
T ss_pred             cccchHHHHHHHHhcCcccCCCCCCCCCCc-eeEeCCCCCCCCcEEEEEEEEeCCEEEEEEEEEEeeeEEeccccEEecC
Confidence            11 12234667788888998       778 8999999999888999998743212368899999976444444677864


No 23
>6B7H_A Metabotropic glutamate receptor 3; mGluR3 Glutamate, MEMBRANE PROTEIN-AGONIST complex; HET: NAG, CWY; 2.82A {Homo sapiens}
Probab=99.85  E-value=1.6e-26  Score=260.59  Aligned_cols=462  Identities=47%  Similarity=0.846  Sum_probs=275.1  Template_Neff=10.800

Q NP_000836.2      37 AHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQS  116 (908)
Q Consensus        37 ~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~  116 (908)
                      ......+++++||+++|.++.......|+......+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+
T Consensus        32 ~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~~~~~A~~~iN~~~~~~~g~~l~l~~~d~~~~~~~a~~~~  111 (517)
T 6B7H_A           32 RREIKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQS  111 (517)
T ss_dssp             CCCEEC-CCEEEEEEECCEEC----CCCCEECCCCCCCHHHHHHHHHHHHTTCSSSSTTCCEEEEEEECTTCHHHHHHHH
T ss_pred             hcceeecCCEEEEEEeeceecCCCCCCCccccccccHHHHHHHHHHHHHHhcCCCCCCCCeEeEEEEeCCCCHHHHHHHH
Confidence            34456688999999999987543233454332235677889999999999998888888999999999887755444333


Q NP_000836.2     117 LTFVQALIEK-DASDVKCANGDPPIF-TKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSR  194 (908)
Q Consensus       117 ~~~~~~l~~~-~~~~~~~~~~~~~~~-~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~  194 (908)
                      .+++.+.... +.....|........ ....++++++|+.++.....++.++...++|+|++.+..+.+.+...++++++
T Consensus       112 ~~l~~~~~~~~~~~~~~c~~~~~~~~~~~~~~v~~iig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~  191 (517)
T 6B7H_A          112 LEFVRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFAR  191 (517)
T ss_dssp             GGGTSTTC---------------------CCCEEEEECCSSHHHHHHHHHHHHTTTCCEEESSCCCGGGGCTTTCTTEEE
T ss_pred             HHHHHhcccccchhhhcCCCCChhhhcCCCcceEEEEcCCCcHHHHHHHHHHHHhCCCeeecccCCcccCCccccCceee
Confidence            3333210000 000000000000000 00025788999888877778888899999999998876665554445789999


Q NP_000836.2     195 VVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       195 ~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      +.|+....+.++++++.+++|++++++++++.++....+.+++.+++. ++++.....++......++...+++++...+
T Consensus       192 ~~p~~~~~~~al~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~l~~i~~~~~  270 (517)
T 6B7H_A          192 TVPPDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLR-NISIATAEKVGRSNIRKSYDSVIRELLQKPN  270 (517)
T ss_dssp             SSCCHHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHT-TCEEEEEEEESSSTTSCCHHHHHHHHHTCTT
T ss_pred             eCCCcHHHHHHHHHHHHHcCCcEEEEEEecCcchHHHHHHHHHHHHHC-CCEEEEEEecCcccccccHHHHHHHHHcCCC
Confidence            999999999999999988999999999987778888888888887765 3555433222211122345556666631247


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNR  354 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~  354 (908)
                      +|+|++......+..+++++++.|+  ++.|++.+.|...............+.+.+.........+..++....+....
T Consensus       271 ~~~vvl~~~~~~~~~~l~~~~~~g~--~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~  348 (517)
T 6B7H_A          271 ARVVVLFMRSDDSRELIAAASRANA--SFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNH  348 (517)
T ss_dssp             CCEEEEECCHHHHHHHHHHHHTTTC--CCEEEECTTTTTCHHHHTTCHHHHTTCEEEEECCCCCHHHHHHHHHCCTTTCC
T ss_pred             ceEEEEECChHHHHHHHHHHHHcCC--CEEEEEecchhccchhhcCCcceecceEEEEEcccCCccHHHHHHhCCCCCCC
Confidence            8888887777778889998888876  35677665544321110001122333333322222222333332221111122


Q NP_000836.2     355 RNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM  434 (908)
Q Consensus       355 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~  434 (908)
                      ...++.++|++.+.+.....   ......|...+.... .......++.++|||++++++|++++....+......|...
T Consensus       349 ~~~~~~~~~~~~~~~~~~~~---~~~~~~~~~~~~~~~-~~~~~~~~~~~~ydav~~~a~al~~~~~~~~~~~~~~c~~~  424 (517)
T 6B7H_A          349 RNPWFRDFWEQKFQCSLQNK---RNHRRVCDKHLAIDS-SNYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAM  424 (517)
T ss_dssp             SCTTHHHHHHHHTTCBC----------CBCCTTCCCCT-TTCCCCTTHHHHHHHHHHHHHHHHHHHHHHCTTCSSCCGGG
T ss_pred             CChHHHHHHHHHcCCccCCc---ccCCcccccccccCC-CccccccchhHHHHHHHHHHHHHHHHHHhhCCCCCCcchhh
Confidence            33456666666554421100   000011211110000 00123456788999999999999998764432211223211


Q NP_000836.2     435 ST-IDGKELLGYIRAVNFNG-------SAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAH  506 (908)
Q Consensus       435 ~~-~~~~~l~~~l~~~~f~G-------~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~  506 (908)
                      .. ..+..+.+.+++..|.|       .+| ++.||.+|++...+.|++++..++...++.||.|+....++...+.|++
T Consensus       425 ~~~~~~~~l~~~l~~~~f~g~~~~~~~~tG-~v~fd~~G~r~~~~~i~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~~  503 (517)
T 6B7H_A          425 KILDGKKLYKDYLLKINFTAPFNPNKDADS-IVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSR  503 (517)
T ss_dssp             SSCCHHHCCCCCCSCEEECCC-----CCTT-EEECCTTSCCCCCEEEEEEEESSSSEEEEEEEEESSSEEECGGGCCCSC
T ss_pred             cccchHHHHHHHHhcCcccCCCCCCCCCCc-eeEeCCCCCCCCcEEEEEEEEeCCEEEEEEEEEEeeeEEeccccEEecC
Confidence            11 12234667788888998       778 8999999999888999998743212368899999976444444677864


No 24
>1EWK_B METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1; SIGNAL TRANSDUCTION, NEUROTRANSMITTER, CNS, NEURON; HET: EPE, NAG, GLU; 2.2A {Rattus norvegicus} SCOP: c.93.1.1
Probab=99.85  E-value=1.8e-26  Score=258.44  Aligned_cols=464  Identities=42%  Similarity=0.763  Sum_probs=275.1  Template_Neff=11.000

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYAL  113 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~  113 (908)
                      .....+++++||+++|+++...    ....|+......+.+...|+++|++++|+++++++++++++.+.|+++++..+.
T Consensus         5 ~~~~~~~~~~ig~l~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~a~~~in~~~~~~~~~~i~~~~~d~~~~~~~~~   84 (490)
T 1EWK_B            5 SVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVAL   84 (490)
T ss_dssp             CCEEECCSEEEEEEECSBCCCCGGGTTTTCCCSBCCCCCCHHHHHHHHHHHHHHTCSSSSTTCCEEEEEEECTTSHHHHH
T ss_pred             ceeEecCCEEEEEEEEeccCCCCCCCCCCCcccccccccHHHHHHHHHHHHHHhcCCCCCCCceEeeEEEecCCCHHHHH
Confidence            3456778999999999987532    134676544445677889999999999998877788999999999988765444


Q NP_000836.2     114 EQSLTFVQALIE----KDASDVKCANGDP--PIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNT  187 (908)
Q Consensus       114 ~~~~~~~~~l~~----~~~~~~~~~~~~~--~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~  187 (908)
                      +.+.+++.....    +......|...+.  ......+++++++|+.++.....++.++...++|+|++.+..+.+.+..
T Consensus        85 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~  164 (490)
T 1EWK_B           85 EQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKT  164 (490)
T ss_dssp             HHHHHHHC-----------------------------CCEEEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTT
T ss_pred             HHHHHHHHHccccccCCcccccccCCCCCCCCCCCCCCCeEEEEcCCCchHHHHHHHHhhhhCCCEEEeccCchhhcCcc
Confidence            443333321000    0000000000000  0000015788999988877777778888999999999877665554433


Q NP_000836.2     188 RYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIK  267 (908)
Q Consensus       188 ~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~  267 (908)
                      .+++++++.++....+.++++++++++|++|++++.++.++....+.+++.+++. ++++.....+.......++...++
T Consensus       165 ~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~vl~~~~~~~~~~~~~~~~~~~~~-g~~i~~~~~~~~~~~~~~~~~~~~  243 (490)
T 1EWK_B          165 LYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQE-GLCIAHSDKIYSNAGEKSFDRLLR  243 (490)
T ss_dssp             TCTTEEESSCCTHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEECTTCCHHHHHHHHH
T ss_pred             cccceeecCCChHHHHHHHHHHHHHcCCCEEEEEEeCCccchhhHHHHHHHHHHc-CceEEEeeEeccccchHHHHHHHH
Confidence            4689999999988889999999988899999999987778887888888877765 355543321211112335566677


Q NP_000836.2     268 RLLETP--NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       268 ~l~~~~--~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      +++. .  +.++|++......+..+++++++.|+.+++.|++.+.|...............+.+.+.........+..++
T Consensus       244 ~l~~-~~~~~~~iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  322 (490)
T 1EWK_B          244 KLRE-RLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYF  322 (490)
T ss_dssp             HHHH-TTTTCCEEEEECCHHHHHHHHHHHHHHTCCSCCEEEECTTTTTCHHHHTTCHHHHTTCEEEEECCCCCHHHHHHH
T ss_pred             HHHH-hCCCCeEEEEEcChHHHHHHHHHHHHcCCCCeeEEEecccccCchhhhhccccccceeEEEEecCCCCCCHHHHH
Confidence            7753 3  457787776666778899999888875445677665443321100001111223222221111112222222


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGK-RNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC  424 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~  424 (908)
                      ........+...++.++|++.+.+....... .......|++++....  ......+++.+|||++++++|++++....+
T Consensus       323 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~yDav~~~a~al~~~~~~~~  400 (490)
T 1EWK_B          323 LKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEE--NYVQDSKMGFVINAIYAMAHGLQNMHHALC  400 (490)
T ss_dssp             TTCCTTTCCSCTTHHHHHHHHTTCBCTTCTTCCTTCCSBCCSCCCTTT--TCCCCTTHHHHHHHHHHHHHHHHHHHHHHS
T ss_pred             HhCCCCCCCCCCcHHHHHHHHcCccCCcccCCCCccCccCCCCccccc--ccccccchHHHHHHHHHHHHHHHHHHHHhC
Confidence            1111111123345666666665542210000 0000112322111100  011345677899999999999998865433


Q NP_000836.2     425 PGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTP-VTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVED  501 (908)
Q Consensus       425 ~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~-v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~~  501 (908)
                      ......|......++..+.+.|++..|.|.+| . +.||++|++...+.|.+++..+ +...++.||.|+... .++...
T Consensus       401 ~~~~~~c~~~~~~~~~~l~~~l~~~~f~G~tG-~~v~fd~~g~~~~~~~i~~~~~~~~~~~~~~~vg~~~~~~~~~~~~~  479 (490)
T 1EWK_B          401 PGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSG-EEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYK  479 (490)
T ss_dssp             TTCSSCCGGGSSCCHHHHHHHHHTCCEECTTS-CEECCCTTSCCCCEEEEEEEEECSSSCEEEEEEEEEETTEEEECTTT
T ss_pred             CCCCCCchhcCCCCHHHHHHHHhcCceecCCC-CeEEECCCCCCCCeEEEEEEEEccCCeeEEEEEEEEECCEEEEccce
Confidence            21112232222235667888898889999998 7 9999999988888888887432 223689999999762 233346


Q NP_000836.2     502 MQWAH  506 (908)
Q Consensus       502 i~w~~  506 (908)
                      +.|++
T Consensus       480 ~~w~~  484 (490)
T 1EWK_B          480 IQMNK  484 (490)
T ss_dssp             C----
T ss_pred             eeecC
Confidence            78865


No 25
>1EWT_A METABOTROPIC GLUTAMATE RECEPTOR SUBTYPE 1; SIGNAL TRANSDUCTION, NEUROTRANSMITTER, CNS, NEURON; HET: SO4, NAG; 3.7A {Rattus norvegicus} SCOP: c.93.1.1
Probab=99.85  E-value=1.8e-26  Score=258.44  Aligned_cols=464  Identities=42%  Similarity=0.763  Sum_probs=275.4  Template_Neff=11.000

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGE----RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYAL  113 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~----~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~  113 (908)
                      .....+++++||+++|+++...    ....|+......+.+...|+++|++++|+++++++++++++.+.|+++++..+.
T Consensus         5 ~~~~~~~~~~ig~l~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~a~~~in~~~~~~~~~~i~~~~~d~~~~~~~~~   84 (490)
T 1EWT_A            5 SVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVAL   84 (490)
T ss_dssp             CEEEECCSEEEEEEECCBCCCCGGGTTTTCCCSBCCCCCCCHHHHHHHHHHHHHHCSSSSTTCCEEEEEEECTTCHHHHH
T ss_pred             ceeEecCCEEEEEEEEeccCCCCCCCCCCCcccccccccHHHHHHHHHHHHHHhcCCCCCCCceEeeEEEecCCCHHHHH
Confidence            3456778999999999987532    134676544445677889999999999998877788999999999988765444


Q NP_000836.2     114 EQSLTFVQALIE----KDASDVKCANGDP--PIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNT  187 (908)
Q Consensus       114 ~~~~~~~~~l~~----~~~~~~~~~~~~~--~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~  187 (908)
                      +.+.+++.....    +......|...+.  ......+++++++|+.++.....++.++...++|+|++.+..+.+.+..
T Consensus        85 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~  164 (490)
T 1EWT_A           85 EQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKT  164 (490)
T ss_dssp             HHHHHHHHHHHHTTC----------------------CCEEEEECCSCHHHHHHHHHHHTTTTCCEEESSCCCGGGGCTT
T ss_pred             HHHHHHHHHccccccCCcccccccCCCCCCCCCCCCCCCeEEEEcCCCchHHHHHHHHhhhhCCCEEEeccCchhhcCcc
Confidence            443333321000    0000000000000  0000015788999988877777778888999999999877665554433


Q NP_000836.2     188 RYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIK  267 (908)
Q Consensus       188 ~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~  267 (908)
                      .+++++++.++....+.++++++++++|++|++++.++.++....+.+++.+++. ++++.....+.......++...++
T Consensus       165 ~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~vl~~~~~~~~~~~~~~~~~~~~~-g~~i~~~~~~~~~~~~~~~~~~~~  243 (490)
T 1EWT_A          165 LYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQE-GLCIAHSDKIYSNAGEKSFDRLLR  243 (490)
T ss_dssp             TCTTEEESSBCSHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHH-CCEEEEEEEECTTCCHHHHHHHHH
T ss_pred             cccceeecCCChHHHHHHHHHHHHHcCCCEEEEEEeCCccchhhHHHHHHHHHHc-CceEEEeeEeccccchHHHHHHHH
Confidence            4689999999988889999999988899999999987778887888888877765 355543321211112335566677


Q NP_000836.2     268 RLLETP--NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       268 ~l~~~~--~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      +++. .  +.++|++......+..+++++++.|+.+++.|++.+.|...............+.+.+.........+..++
T Consensus       244 ~l~~-~~~~~~~iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  322 (490)
T 1EWT_A          244 KLRE-RLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYF  322 (490)
T ss_dssp             HHHH-TTTTTTEEEEECCHHHHHHHHHHHHHTTCCSSCEEEECTTTTTCTTTSSSTTTTTTTCEEEEECCCCCHHHHHHH
T ss_pred             HHHH-hCCCCeEEEEEcChHHHHHHHHHHHHcCCCCeeEEEecccccCchhhhhccccccceeEEEEecCCCCCCHHHHH
Confidence            7753 3  457787776666778899999888875445677665443321100001111223222221111112222222


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGK-RNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC  424 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~  424 (908)
                      ........+...++.++|++.+.+....... .......|++++....  ......+++.+|||++++++|++++....+
T Consensus       323 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~--~~~~~~~~~~~yDav~~~a~al~~~~~~~~  400 (490)
T 1EWT_A          323 LKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEE--NYVQDSKMGFVINAIYAMAHGLQNMHHALC  400 (490)
T ss_dssp             HSCCTTTCCSCTTHHHHHHHHHTCBCSSCSSCCTTCSSBCCSCCCTTT--TCCCCSTHHHHHHHHHHHHHHHHHHHHHHS
T ss_pred             HhCCCCCCCCCCcHHHHHHHHcCccCCcccCCCCccCccCCCCccccc--ccccccchHHHHHHHHHHHHHHHHHHHHhC
Confidence            1111111123345666666665542210000 0000112322111100  011345677899999999999998865433


Q NP_000836.2     425 PGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTP-VTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQL-HLKVED  501 (908)
Q Consensus       425 ~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~-v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~-~~~~~~  501 (908)
                      ......|......++..+.+.|++..|.|.+| . +.||++|++...+.|.+++..+ +...++.||.|+... .++...
T Consensus       401 ~~~~~~c~~~~~~~~~~l~~~l~~~~f~G~tG-~~v~fd~~g~~~~~~~i~~~~~~~~~~~~~~~vg~~~~~~~~~~~~~  479 (490)
T 1EWT_A          401 PGHVGLCDAMKPIDGRKLLDFLIKSSFVGVSG-EEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYK  479 (490)
T ss_dssp             SSCSSCCGGGSSCCHHHHHHHHHTCEEECTTS-CEEECCTTSCBCCEEEEEEEEECSSSCEEEEEEEEEETTEEEECGGG
T ss_pred             CCCCCCchhcCCCCHHHHHHHHhcCceecCCC-CeEEECCCCCCCCeEEEEEEEEccCCeeEEEEEEEEECCEEEEccce
Confidence            21112232222235667888898889999998 7 9999999988888888887432 223689999999762 233346


Q NP_000836.2     502 MQWAH  506 (908)
Q Consensus       502 i~w~~  506 (908)
                      +.|++
T Consensus       480 ~~w~~  484 (490)
T 1EWT_A          480 IQMNK  484 (490)
T ss_dssp             C----
T ss_pred             eeecC
Confidence            78865


No 26
>5C5C_A Metabotropic glutamate receptor 7; GLUTAMATE RECEPTORS, GLUTAMIC ACID BINDING; HET: NAG, UNX; 1.862A {Homo sapiens}
Probab=99.85  E-value=2e-26  Score=257.70  Aligned_cols=468  Identities=73%  Similarity=1.247  Sum_probs=271.6  Template_Neff=11.400

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ......++++||+++|.++.......|+......+.....|+++|++++|+++++++|+++++++.|++++.....+.+.
T Consensus         9 ~~~~~~~~i~ig~~~p~~~~~~~~~~~~~~~~~~g~~~~~~~~~A~~~in~~~~~~~g~~i~~~~~d~~~~~~~~~~~~~   88 (481)
T 5C5C_A            9 HSIRIEGDVTLGGLFPVHAKGPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL   88 (481)
T ss_dssp             CEEEECCSEEEEEEECCEEECSSSCSEEEECCCCCCCHHHHHHHHHHHHHTCTTSSTTCCEEEEEEECTTCHHHHHHHHG
T ss_pred             ceeEeCCCEEEEEEeeeeecCCCCCCCCcccccccHHHHHHHHHHHHHHcCCCCCCCCceeeeEEEcCCCCHHHHHHHHH
Confidence            34566789999999999875332234543333356778899999999999988887789999999988765333233333


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +.+++++........|...........++++++||+.++.....++.++...++|+|++.+..+.+.+...+++++++.+
T Consensus        89 ~~~~~l~~~~~~~~~c~~~~~~~~~~~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~  168 (481)
T 5C5C_A           89 TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYASTAPELSDDRRYDFFSRVVP  168 (481)
T ss_dssp             GGGTTTC------------------CCCCEEEEECCSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCTTTCTTEEESSC
T ss_pred             HHHHHHHccCCCCcccCCCCCCCccccccEEEEEcCCCcHHHHHHHHHHHHhCCCEEecCCCCcccCCCcccccccccCC
Confidence            33333321000000000000000001257889999988877777888899999999998876655544335788999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE--PRPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~--~~~~~~~~~~~~l~~~~~~  275 (908)
                      +...+++++++++++++|+++++++.++.++....+.+++.+++.+++++.....+...  ....++...+++++...++
T Consensus       169 ~~~~~~~~l~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~~g~~v~~~~~~~~~~~~~~~~~~~~~~~i~~~~~~  248 (481)
T 5C5C_A          169 PDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQISKEAGGLSIAQSVRIPQERKDRTIDFDRIIKQLLDTPNS  248 (481)
T ss_dssp             CHHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHHSSCEEEEEEEECCCCTTCCCCHHHHHHHHHTSSSC
T ss_pred             CCHHHHHHHHHHHHHhCCCEEEEEEeCCchhHHHHHHHHHHHHHcCCceEEEEEEcCCccCCchhcHHHHHHHHHcCCCc
Confidence            99889999999998899999999998777888888888877765423444433222210  0123455566666521368


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR  355 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  355 (908)
                      |+|++......+..+++++++.++..++.|++.+.|...............+.+.+.+.......|..++....+.....
T Consensus       249 ~~vv~~~~~~~~~~~l~~~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  328 (481)
T 5C5C_A          249 RAVVIFANDEDIKQILAAAKRADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR  328 (481)
T ss_dssp             CEEEEEECHHHHHHHHHHHHHSSSCCCEEEEESSCC---------CCCCCTTCEEEEECCCCCHHHHHHHHTCCTTTCTT
T ss_pred             eEEEEEcCHHHHHHHHHHHHHhccCCCEEEEEeccccCCCcccccccceecceEEEEeccccCccHHHHHhcCCCccCCC
Confidence            88888777777888999998887653456776654432210000011122333332221111122222211100011123


Q NP_000836.2     356 NVWFAEFWEENFGCKLGSHGKR-NSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM  434 (908)
Q Consensus       356 ~~~~~~~~~~~~~~~~~~~~~~-~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~  434 (908)
                      ..+|.++|++.+++........ ..+...|................+++++|||+++++.++++.....+....+.|...
T Consensus       329 ~~~f~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~yDav~~~a~al~~~~~~~~~~~~~~c~~~  408 (481)
T 5C5C_A          329 NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAHALHHMNKDLCADYRGVCPEM  408 (481)
T ss_dssp             STTHHHHHHHHTTCBC----------CCBCCSCCCTTTTSCCCCCTTHHHHHHHHHHHHHHHHHHHHHHCCSCSSCCHHH
T ss_pred             ChHHHHHHHHHcCCcCcCCCCCcccCCCCCCCCccccCcccccccccHHHHHHHHHHHHHHHHHHHHhhcCCCCCCChHH
Confidence            3455666665554321100000 000111211100000000122346788999999999999998754332111223221


Q NP_000836.2     435 STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 ~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                      ...++..+.+.|++.+|.|.+|..++||++|++...+.+++++..+ +...++.||.|+....+....+.|.
T Consensus       409 ~~~~~~~l~~~l~~~~f~G~tG~~v~fd~~g~~~~~~~i~~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~  480 (481)
T 5C5C_A          409 EQAGGKKLLKYIRNVNFNGSAGTPVMFNKNGDAPGRYDIFQYQTTNTSNPGYRLIGQWTDELQLNIEDMQWG  480 (481)
T ss_dssp             HHHHHHHHHHHHHTCCEECTTSSEECCCTTSBCCCCEEEEEEECCC---CEEEEEEEESSSEEECGGGSCC-
T ss_pred             HhhcHHHHHHHHhcCceecCCCCeEEeCCCCCCCCeEEEEEEEecCCCCCceEEeEEEccceeEehhhceec
Confidence            1224456778888889999887459999999988788888887432 1245789999997654544467773


No 27
>3SM9_A Metabotropic glutamate receptor 3; Structural Genomics, Structural Genomics Consortium; HET: SO4, Z99; 2.26A {Homo sapiens}
Probab=99.84  E-value=2.4e-26  Score=256.80  Aligned_cols=459  Identities=47%  Similarity=0.859  Sum_probs=274.8  Template_Neff=11.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...+++++||+++|.++.......|+......+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+.++
T Consensus         8 ~~~~~~i~ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~a~~~iN~~~~~~~g~~l~l~~~D~~~~~~~~~~~~~~l   87 (479)
T 3SM9_A            8 IKIEGDLVLGGLFPINEKGTGTEECGRINEDRGIQRLEAMLFAIDEINKDDYLLPGVKLGVHILDTCSRDTYALEQSLEF   87 (479)
T ss_dssp             EEECCSEEEEEEECCEEECC-CCSEEEECCCCCCCHHHHHHHHHHHHHHCSSSSTTCCEEEEEEECTTCHHHHHHHHHHH
T ss_pred             eEecCCEEEEeeeeceecCCCCCCCCcccccccHHHHHHHHHHHHHHhcCCCCCCCCeEEEEEeeCCCCHHHHHHHHHHH
Confidence            45678999999999987543234565433345677889999999999998888788999999999887655444333333


Q NP_000836.2     120 VQALIEK-DASDVKCANGDPPIF-TKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       120 ~~~l~~~-~~~~~~~~~~~~~~~-~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +.+.... +.....|........ ....++++++|+.++.....++.++...++|+|++....+.+.+...+++++++.+
T Consensus        88 ~~~~~~~~~~~~~~c~~~~~~~~~~~~~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~~~~  167 (479)
T 3SM9_A           88 VRASLTKVDEAEYMCPDGSYAIQENIPLLIAGVIGGSYSSVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTVP  167 (479)
T ss_dssp             HHTCC-----------------------CEEEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTTTTTEEESSC
T ss_pred             HHhcccCccchhhcCCCCChhhhcCCCcceEEEEcCCChHHHHHHHHHHHHhCCCEEecCccChhhcCcccCCceeeeCC
Confidence            3210000 000000000000000 00025789999988877778888889999999998776655544335788999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      +....+.++++++.+++|+++++++.++.++....+.+++.+++. ++++.....++......++...++++....++|+
T Consensus       168 ~~~~~~~a~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~i~~~~~~~~  246 (479)
T 3SM9_A          168 PDFYQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFEQEARLR-NISIATAEKVGRSNIRKSYDSVIRELLQKPNARV  246 (479)
T ss_dssp             CTHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHTT-TCEEEEEEEECC--CHHHHHHHHHHHHTCTTCCE
T ss_pred             ChHHHHHHHHHHHHHcCCcEEEEEEecCchhHHHHHHHHHHHHHC-CcEEEEEEEeCcccccccHHHHHHHHHhCCCccE
Confidence            998899999999988999999999987778888888888887775 4555443323211112345556666621247888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      |++......+..+++++++.|+  ++.|++.+.|...............|.+.+.........|..++....+...+.++
T Consensus       247 vvl~~~~~~~~~~l~~~~~~g~--~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  324 (479)
T 3SM9_A          247 VVLFMRSDDSRELIAAASRANA--SFTWVASDGWGAQESIIKGSEHVAYGAITLELASQPVRQFDRYFQSLNPYNNHRNP  324 (479)
T ss_dssp             EEEECCHHHHHHHHHHHHHTTC--CCEEEECTTTTTCHHHHTTCTTTTTTCEEEEECCCCCHHHHHHHHTCCTTTCTTCT
T ss_pred             EEEEcChHHHHHHHHHHHHcCC--CEEEEEeCcccccchhHcCCcceeceeEEEEEccccChhHHHHHHhCCCCCCCCCH
Confidence            8887777778889999888876  35677665444321110001122334333332222222333333222111223345


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTI  437 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~  437 (908)
                      ++.++|++.+.+.....   ......|...+..... ....+.++.++|||++++++|++++....+......|......
T Consensus       325 ~~~~~~~~~~~~~~~~~---~~~~~~c~~~~~~~~~-~~~~~~~~~~~ydav~~~a~al~~~~~~~~~~~~~~c~~~~~~  400 (479)
T 3SM9_A          325 WFRDFWEQKFQCSLQNK---RNHRRVCDKHLAIDSS-NYEQESKIMFVVNAVYAMAHALHKMQRTLCPNTTKLCDAMKIL  400 (479)
T ss_dssp             THHHHHHHHHTCBCCC------CSCBCCTTCCCCTT-TCCCCTTHHHHHHHHHHHHHHHHHHHHHHSTTCSSCCHHHHSC
T ss_pred             HHHHHHHHHcCCccCCc---cCCCCccCccccccCc-cccccccchHHHHHHHHHHHHHHHHHHhhCCCCCCCchhhccc
Confidence            66777776665432110   0001122211111000 0113456778999999999999998764332211223211111


Q NP_000836.2     438 D-GKELLGYIRAVNFNG-------SAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWAH  506 (908)
Q Consensus       438 ~-~~~l~~~l~~~~f~G-------~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~~  506 (908)
                      + +..+.+.|++..|.|       .+| .|.|+++|++...+.+++++..++...++.||.|+....++...+.|++
T Consensus       401 ~~~~~l~~~l~~~~f~g~~~~~~~~~G-~v~f~~~g~r~~~~~i~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~~  476 (479)
T 3SM9_A          401 DGKKLYKDYLLKINFTAPFNPNKDADS-IVKFDTFGDGMGRYNVFNFQNVGGKYSYLKVGHWAETLSLDVNSIHWSR  476 (479)
T ss_dssp             CHHHCCCCCGGGCCEECTTC-----CC-EECCCTTCBCCCCEEEEEEEESSSCEEEEEEEEESSSEEECGGGCCCC-
T ss_pred             ChHHHHHHHHhcCcccCCCCCCCCCCC-eeEeCCCCCCCCcEEEEEEEEeCCeEEEEEEEEEeeeeEecccceeecc
Confidence            1 224667788888988       777 8999999999888899988743212358899999876444434577754


No 28
>4XAQ_A Metabotropic glutamate receptor 2; mGluR2 mGluR3, SIGNALING PROTEIN; HET: 40F, SO4; 2.21A {Homo sapiens}
Probab=99.83  E-value=9.3e-26  Score=253.40  Aligned_cols=453  Identities=45%  Similarity=0.841  Sum_probs=270.3  Template_Neff=10.900

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.+........|+......+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+.++
T Consensus        28 ~~~~~~i~Ig~~~p~~~~~g~~~~c~~~~~~~~~~~~~~~~~a~~~in~~~~~~~~~~i~~~~~d~~~~~~~~~~~~~~l  107 (503)
T 4XAQ_A           28 LTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDF  107 (503)
T ss_dssp             EEECCSEEEEEEECCEEECCTTCSEEEECCCCCCCHHHHHHHHHHHHHHCTTSSTTCCEEEEEEECTTCHHHHHHHHHHH
T ss_pred             EEeCCCEEEEEEeeceeCCCCcccCCcccccccHHHHHHHHHHHHHHhcCCCCCCCCeeeEEEEeCCCCHHHHHHHHHHH
Confidence            46778999999999972211122354332235667889999999999998777778999999999887655443333333


Q NP_000836.2     120 VQALIEK--DASDVKCANGDPPIFT-KPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       120 ~~~l~~~--~~~~~~~~~~~~~~~~-~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +......  ......|...++.|.. ..+++++++|+.++.....++.+++..++|+|++.+..+.+.++..+++++++.
T Consensus       108 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~  187 (503)
T 4XAQ_A          108 VRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTV  187 (503)
T ss_dssp             HTTTC-----------------------CCCCEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTTCTTEEESS
T ss_pred             HHHHhccCCCCCceeCCCCccccCCCCCCceEEEEcCCCcHHHHHHHHHHHHhCCCEEecCCCCccccCccccCceeeeC
Confidence            3210000  0000000000000000 013688999988887777888889999999999877666555444578899999


Q NP_000836.2     197 PPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNAR  276 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~  276 (908)
                      ++....+.++++++++++|+++++++.+++++....+.+++.+++. ++++.....++......++...++++....+++
T Consensus       188 ~~~~~~~~~l~~~l~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~i~~~~~~~  266 (503)
T 4XAQ_A          188 PPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARAR-NISVATSEKVGRAMSRAAFEGVVRALLQKPSAR  266 (503)
T ss_dssp             CCHHHHHHHHHHHHHHHTCCEEEEEEESSTTHHHHHHHHHHHHHHT-TCEEEEEEEECTTCCHHHHHHHHHHHHTCTTCC
T ss_pred             CChHHHHHHHHHHHHHcCCcEEEEEEeCCcchhHHHHHHHHHHHHC-CcEEEeEEecccccCHHHHHHHHHHHHcCCCce
Confidence            9998889999999988999999999987778888888888877765 355543332321012234556666664224788


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      +|++......+..+++++++.|+  ++.|++.+.|...............+.+.+.......+.|..++....+...+..
T Consensus       267 ~iv~~~~~~~~~~~l~~~~~~g~--~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  344 (503)
T 4XAQ_A          267 VAVLFTRSEDARELLAASQRLNA--SFTWVASDGWGALEEVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRN  344 (503)
T ss_dssp             EEEEECCHHHHHHHHHHHHHTTC--CCEEEECTTTTTCHHHHTTCHHHHTTCEEEEESCCCCTTHHHHHHTCCTTTCCSC
T ss_pred             EEEEEcChHHHHHHHHHHHHhCC--CEEEEEeCCcccchHHHhcCcccccceEEEEeccccCccHHHHHHcCCcCCCCCC
Confidence            88887777778888988888877  3567766544332110000112233444333222222233322221111111233


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMST  436 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~  436 (908)
                      .++.++|++.+.+....        ..|..... .. ....+..++..+|||+++++.|+++.....+......|.....
T Consensus       345 ~~~~~~~~~~~~~~~~~--------~~~~~~~~-~~-~~~~~~~~a~~~yDav~~~a~al~~~~~~~~~~~~~~c~~~~~  414 (503)
T 4XAQ_A          345 PWFREFWEQRFRCSFRQ--------RDCAAHSL-RA-VPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRP  414 (503)
T ss_dssp             TTHHHHHHHHTTCCSSS--------CCCSSCCT-TT-SCCCCCTTHHHHHHHHHHHHHHHHHHHHHHCCSCSSCCGGGSS
T ss_pred             HHHHHHHHHHhCCccCC--------CCCCCccc-cc-CCcccccchhHHHHHHHHHHHHHHHHHHHHCCCCCCCchhcCC
Confidence            45666666655542110        01211100 00 0012334577899999999999999875433221122322112


Q NP_000836.2     437 IDGKE-LLGYIRAVNFN------GSAGTPVTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQLHLKVEDMQWAH  506 (908)
Q Consensus       437 ~~~~~-l~~~l~~~~f~------G~~G~~v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~~~~~~~i~w~~  506 (908)
                      .++.. +.+.|++..|.      |.+| .++||++|++...+.+++++..+ +...++.||.|++...++...+.|++
T Consensus       415 ~~~~~~~~~~l~~~~f~~~~~~~G~~G-~v~fd~~g~~~~~~~v~~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~~  491 (503)
T 4XAQ_A          415 VNGRRLYKDFVLNVKFDAPFRPADTHN-EVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWAS  491 (503)
T ss_dssp             CCHHHCCCCCGGGCCEECTTCCSSCCC-EECCCTTSCCCCCEEEEEEEECTTSCEEEEEEEEESSSEEECGGGSCC--
T ss_pred             cCHHHHHHHHHHhCeecCCCCCCCCCC-cEEeCCCCCCCCeEEEEEEEEcCCCceEEEEEEEEcCCcEEccceeeecC
Confidence            23334 33567777787      7888 89999999998888888887431 12258899999976544444678865


No 29
>5CNI_A Metabotropic glutamate receptor 2; receptor, glutamate, metabotropic, SIGNALING PROTEIN; HET: GGL, NAG; 2.69A {Homo sapiens}
Probab=99.83  E-value=9.3e-26  Score=253.40  Aligned_cols=453  Identities=45%  Similarity=0.841  Sum_probs=270.0  Template_Neff=10.900

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.+........|+......+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+.++
T Consensus        28 ~~~~~~i~Ig~~~p~~~~~g~~~~c~~~~~~~~~~~~~~~~~a~~~in~~~~~~~~~~i~~~~~d~~~~~~~~~~~~~~l  107 (503)
T 5CNI_A           28 LTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDF  107 (503)
T ss_dssp             EEECCSEEEEEEECCEEECCSSCSEEEECCCCCCCHHHHHHHHHHHHTTCTTSSTTCCEEEEEEECTTCHHHHHHHHHHH
T ss_pred             EEeCCCEEEEEEeeceeCCCCcccCCcccccccHHHHHHHHHHHHHHhcCCCCCCCCeeeEEEEeCCCCHHHHHHHHHHH
Confidence            46778999999999972211122354332235667889999999999998777778999999999887655443333333


Q NP_000836.2     120 VQALIEK--DASDVKCANGDPPIFT-KPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       120 ~~~l~~~--~~~~~~~~~~~~~~~~-~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +......  ......|...++.|.. ..+++++++|+.++.....++.+++..++|+|++.+..+.+.++..+++++++.
T Consensus       108 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~  187 (503)
T 5CNI_A          108 VRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFARTV  187 (503)
T ss_dssp             HSCC------------------------CCCCEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTTCTTEEESS
T ss_pred             HHHHhccCCCCCceeCCCCccccCCCCCCceEEEEcCCCcHHHHHHHHHHHHhCCCEEecCCCCccccCccccCceeeeC
Confidence            3210000  0000000000000000 013688999988887777888889999999999877666555444578899999


Q NP_000836.2     197 PPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNAR  276 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~  276 (908)
                      ++....+.++++++++++|+++++++.+++++....+.+++.+++. ++++.....++......++...++++....+++
T Consensus       188 ~~~~~~~~~l~~~l~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~i~~~~~~~  266 (503)
T 5CNI_A          188 PPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARAR-NISVATSEKVGRAMSRAAFEGVVRALLQKPSAR  266 (503)
T ss_dssp             CCTHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHTT-TCEEEEEEEECSSCCHHHHHHHHHHHHTCTTCC
T ss_pred             CChHHHHHHHHHHHHHcCCcEEEEEEeCCcchhHHHHHHHHHHHHC-CcEEEeEEecccccCHHHHHHHHHHHHcCCCce
Confidence            9998889999999988999999999987778888888888877765 355543332321012234556666664224788


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      +|++......+..+++++++.|+  ++.|++.+.|...............+.+.+.......+.|..++....+...+..
T Consensus       267 ~iv~~~~~~~~~~~l~~~~~~g~--~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  344 (503)
T 5CNI_A          267 VAVLFTRSEDARELLAASQRLNA--SFTWVASDGWGALEEVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRN  344 (503)
T ss_dssp             EEEEECCHHHHHHHHHHHHHTTC--CCEEEECTTTTTCHHHHTTCHHHHTTCEEEEECCCCCHHHHHHHHTCCTTTCCSC
T ss_pred             EEEEEcChHHHHHHHHHHHHhCC--CEEEEEeCCcccchHHHhcCcccccceEEEEeccccCccHHHHHHcCCcCCCCCC
Confidence            88887777778888988888877  3567766544332110000112233444333222222233322221111111233


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMST  436 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~  436 (908)
                      .++.++|++.+.+....        ..|..... .. ....+..++..+|||+++++.|+++.....+......|.....
T Consensus       345 ~~~~~~~~~~~~~~~~~--------~~~~~~~~-~~-~~~~~~~~a~~~yDav~~~a~al~~~~~~~~~~~~~~c~~~~~  414 (503)
T 5CNI_A          345 PWFREFWEQRFRCSFRQ--------RDCAAHSL-RA-VPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRP  414 (503)
T ss_dssp             TTHHHHHHHHHTCCCC---------CCSTTCCT-TT-SCCCCCTTHHHHHHHHHHHHHHHHHHHHHHCTTCSSCCGGGSS
T ss_pred             HHHHHHHHHHhCCccCC--------CCCCCccc-cc-CCcccccchhHHHHHHHHHHHHHHHHHHHHCCCCCCCchhcCC
Confidence            45666666655542110        01211100 00 0012334577899999999999999875433221122322112


Q NP_000836.2     437 IDGKE-LLGYIRAVNFN------GSAGTPVTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQLHLKVEDMQWAH  506 (908)
Q Consensus       437 ~~~~~-l~~~l~~~~f~------G~~G~~v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~~~~~~~i~w~~  506 (908)
                      .++.. +.+.|++..|.      |.+| .++||++|++...+.+++++..+ +...++.||.|++...++...+.|++
T Consensus       415 ~~~~~~~~~~l~~~~f~~~~~~~G~~G-~v~fd~~g~~~~~~~v~~~~~~~~~~~~~~~vg~~~~~~~~~~~~~~w~~  491 (503)
T 5CNI_A          415 VNGRRLYKDFVLNVKFDAPFRPADTHN-EVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWAS  491 (503)
T ss_dssp             CCHHHCCCCCGGGCCEECTTCCTTCCC-EECCCTTSCCCCEEEEEEEEECC--CEEEEEEEEEESSEEECTTSSCC--
T ss_pred             cCHHHHHHHHHHhCeecCCCCCCCCCC-cEEeCCCCCCCCeEEEEEEEEcCCCceEEEEEEEEcCCcEEccceeeecC
Confidence            23334 33567777787      7888 89999999998888888887431 12258899999976544444678865


No 30
>5CNJ_A Metabotropic glutamate receptor 2; glutamate receptor analog, SIGNALING PROTEIN; HET: 52Q, NAG; 2.65A {Homo sapiens}
Probab=99.83  E-value=1.1e-25  Score=252.80  Aligned_cols=454  Identities=45%  Similarity=0.841  Sum_probs=271.0  Template_Neff=10.800

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||+++|.+........|+......+.....|+++|++++|+++++++|+++++.+.|+++++..+.+.+.+
T Consensus        27 ~~~~~~~i~Ig~~~p~~~~~g~~~~c~~~~~~~~~~~~~~~~~a~~~in~~~~~~~~~~i~~~~~d~~~~~~~~~~~~~~  106 (503)
T 5CNJ_A           27 VLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALD  106 (503)
T ss_dssp             CEEECCSEEEEEEECCEEECCTTCSEEEECCCCCCCHHHHHHHHHHHHTTCSSSSSSCCEEEEEEECTTCHHHHHHHGGG
T ss_pred             eEEeCCCEEEEEeeecccCCCCCCCCCCccccccHHHHHHHHHHHHHHhcCCCCCCCCeeeEEEEcCCCCHHHHHHHHHH
Confidence            35677899999999997321112235433223456788999999999999877777899999999988775544433333


Q NP_000836.2     119 FVQALIE--KDASDVKCANGDPPIF-TKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRV  195 (908)
Q Consensus       119 ~~~~l~~--~~~~~~~~~~~~~~~~-~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~  195 (908)
                      ++.....  .......|...++.+. ...++++++||+.++.....++.++...++|+|++.+..+.+.++..+++++++
T Consensus       107 l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~  186 (503)
T 5CNJ_A          107 FVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDYFART  186 (503)
T ss_dssp             GTTTTC----------------------CCCEEEEEECSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCTTTCTTEEES
T ss_pred             HHHHHhccCCCCCceeCCCCccccCCCCCCceEEEEcCCCcHHHHHHHHHHHHhCCCEEecCcCCccccCCccCCceeee
Confidence            3321000  0000000000000000 001468899998887777778888899999999988766655443357889999


Q NP_000836.2     196 VPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~  275 (908)
                      .++....+.++++++++++|++|++++.+++++....+.+++.+++. ++++.....++......++...++++.+..++
T Consensus       187 ~p~~~~~~~a~~~~l~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~  265 (503)
T 5CNJ_A          187 VPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARAR-NISVATSEKVGRAMSRAAFEGVVRALLQKPSA  265 (503)
T ss_dssp             SCCHHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHT-TCEEEEEEEECSSCCHHHHHHHHHHHHTSSSC
T ss_pred             CCChHHHHHHHHHHHHHcCCcEEEEEEeCCcchhHHHHHHHHHHHHC-CcEEEEEEecccccCHHHHHHHHHHHHcCCCc
Confidence            99998889999999988899999999987778888888888887765 35554332232101223455666666422478


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR  355 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  355 (908)
                      |+|++......+..+++++++.|+  ++.|++.+.|...............|.+.+.......+.|..++....+...+.
T Consensus       266 ~~iv~~~~~~~~~~~l~~~~~~g~--~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  343 (503)
T 5CNJ_A          266 RVAVLFTRSEDARELLAASQRLNA--SFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSR  343 (503)
T ss_dssp             CEEEEECCHHHHHHHHHHHHHTTC--CCEEEECTTTTTCHHHHTTCHHHHTTCEEEEECCCCCHHHHHHHHTCCTTTCTT
T ss_pred             eEEEEEcChHHHHHHHHHHHHhCC--CEEEEEeCccccchhHHccCcccccceEEEEeccccCccHHHHHhcCCCCCCCC
Confidence            888887766677888888888776  356776654433211000011233344433322222222322222111111123


Q NP_000836.2     356 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMS  435 (908)
Q Consensus       356 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~  435 (908)
                      ..++.++|++.+.+....        ..|.... ... .......++..+|||++++++|+++.....+......|....
T Consensus       344 ~~~f~~~~~~~~~~~~~~--------~~~~~~~-~~~-~~~~~~~~~~~~yDav~~~a~al~~~~~~~~~~~~~~c~~~~  413 (503)
T 5CNJ_A          344 NPWFREFWEQRFRCSFRQ--------RDCAAHS-LRA-VPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMR  413 (503)
T ss_dssp             CTTHHHHHHHHTTCCGGG--------TCSTTCC-TTT-SCCCCCTTHHHHHHHHHHHHHHHHHHHHHHCCSCSSCCGGGS
T ss_pred             CHHHHHHHHHHhCCccCc--------ccCCCcc-ccc-CCccccccchHHHHHHHHHHHHHHHHHHHhCCCCCCcchhcC
Confidence            345666666655442110        0111100 000 001123456789999999999999886543221112232211


Q NP_000836.2     436 TIDGKE-LLGYIRAVNFN------GSAGTPVTFNENGDAPGRYDIFQYQITN-KSTEYKVIGHWTNQLHLKVEDMQWAH  506 (908)
Q Consensus       436 ~~~~~~-l~~~l~~~~f~------G~~G~~v~Fd~~G~~~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~~~~~~~i~w~~  506 (908)
                      ..++.. +.+.|++.+|.      |.+| .++||++|++...+.+++++..+ +...+++||.|+....++...+.|++
T Consensus       414 ~~~~~~~l~~~l~~~~f~~~~~~~g~tG-~i~fd~~g~r~~~~~i~~~~~~~~~~~~~~~vg~w~~~~~~~~~~~~w~~  491 (503)
T 5CNJ_A          414 PVNGRRLYKDFVLNVKFDAPFRPADTHN-EVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWAS  491 (503)
T ss_dssp             SCCHHHCCCCCGGGCEEECTTCCTTCCC-EEECCTTSCCCCEEEEEEEEECTTSCEEEEEEEEEESSEEECGGGSTTC-
T ss_pred             ccCHHHHHHHHHHhCeecCCCCCCCCCC-cEEeCCCCCCCCeEEEEEEEEcCCCceEEEEEEEEccCcEEccccceecC
Confidence            123333 44667777887      5788 89999999998888888887432 12358999999976555445678875


No 31
>5FBK_A Extracellular calcium-sensing receptor; membrane protein, G-protein coupled receptor; HET: NAG, CSO, TCR; 2.1A {Homo sapiens}
Probab=99.81  E-value=3.8e-25  Score=252.03  Aligned_cols=460  Identities=32%  Similarity=0.552  Sum_probs=275.6  Template_Neff=10.500

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGE----------RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD  109 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~----------~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~  109 (908)
                      ...+++++||+++|.++...          ....|+... ..+.....|++.|++++|+++++++|+++++++.|+++++
T Consensus        53 ~~~~~~i~Ig~l~p~~~~~~~~~~~~~~~~~~~~c~~~~-~~~~~~~~~~~~a~~~in~~~~~~~g~~i~~~~~D~~~~~  131 (568)
T 5FBK_A           53 AQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYN-FRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTV  131 (568)
T ss_dssp             EEECCSEEEEEEECSEEEECCCCCCCSSCCCCCCEEEEC-HHHHHHHHHHHHHHHHHHTCSSSSSSCCEEEEEEECTTCH
T ss_pred             eeecCCEEEEEeeeeeecccccCCCccCCCCcccceecc-cccHHHHHHHHHHHHHHhcCCCCCCCCEEeeEEEeCCCCH
Confidence            45678999999999986431          123455422 2456788999999999999888888899999999988775


Q NP_000836.2     110 TYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRY  189 (908)
Q Consensus       110 ~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~  189 (908)
                      ..+.+.+.+++.+-    ..+.....+.+.+....++++++||+.++..+..++.++...++|+|++.+..+.+.+...+
T Consensus       132 ~~a~~~~~~l~~~~----~~~~~~~~~~~~~~~~~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~  207 (568)
T 5FBK_A          132 SKALEATLSFVAQN----KIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQF  207 (568)
T ss_dssp             HHHHHHHHHHTHHH----HHHHHTHHHHSCCCSCCCCEEEEECCSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCTTTC
T ss_pred             HHHHHHHHHHHHhc----CcccCCccccccCCCCCCCeEEEEcCCCcHHHHHHHHHHhhhCCcEeccccCCcccCCcccC
Confidence            54443333333210    00000000000011111357899998888777788888899999999988766555443357


Q NP_000836.2     190 DFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRL  269 (908)
Q Consensus       190 ~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l  269 (908)
                      ++++++.+++...+.++++++++++|++|++++.++.++....+.+++.+++. ++++.....+.......++...++++
T Consensus       208 ~~~~~~~~~~~~~~~a~~~~~~~~~~~~v~vi~~~~~~~~~~~~~~~~~~~~~-gi~v~~~~~~~~~~~~~~~~~~~~~l  286 (568)
T 5FBK_A          208 KSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEER-DICIDFSELISQYSDEEEIQHVVEVI  286 (568)
T ss_dssp             TTEEESSCCTHHHHHHHHHHHHHTTCCSEEEEEESSTTHHHHHHHHHHHHHHT-TCCEEEEEEECTTCCHHHHHHHHHHH
T ss_pred             CceeecCCCchHHHHHHHHHHHHcCCcEEEEEEecCccchhHHHHHHHHHHHC-CeEEEEEEeecCCCCHHHHHHHHHHH
Confidence            88999999998889999999988999999999977778888888888888775 46665433222101223455667777


Q NP_000836.2     270 LETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPV-YQQEEIAEGAVTILPKRASIDGFDRYFRSR  348 (908)
Q Consensus       270 ~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~-~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~  348 (908)
                      +. .++|+|++.+....+..+++++++.|+.. ..|++.+.|....... ........+.+.+.........|..|....
T Consensus       287 ~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~i~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~f~~~~~~~  364 (568)
T 5FBK_A          287 QN-STAKVIVVFSSGPDLEPLIKEIVRRNITG-KIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKV  364 (568)
T ss_dssp             HH-CCCCEEEEECCHHHHHHHHHHHHHTTCCS-CEEEECHHHHTCTTTCCGGGHHHHTTCEEEEECCBCCTTHHHHHHTC
T ss_pred             Hh-CCCeEEEEEcCchhHHHHHHHHHHcCCCC-CEEEEehhhcccccccCccceeeeceEEEEEeccccCccHHHHHHhc
Confidence            63 57899888877777888999988888753 4566665443321100 000111223333332222233333333221


Q NP_000836.2     349 TLANNRRNVWFAEFWEENFGCKLGSHGK----------------------RNSHIKKCTGLERIAR----DSSYEQEGKV  402 (908)
Q Consensus       349 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------------------~~~~~~~c~~~~~~~~----~~~~~~~~~~  402 (908)
                      .+.......++.++|++.+.|.......                      ...+...|+..+....    ........++
T Consensus       365 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~a  444 (568)
T 5FBK_A          365 HPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRIS  444 (568)
T ss_dssp             CTTTCSSBTTHHHHHHHHHTCBC-------------------------------CCBCCSCCCGGGSCCTTTCCSCBSHH
T ss_pred             CCccCCCChhHHHHHHHHhCCccCCCCCCCCCchhcccCccccCCccCCCCcCCCCCCCCCCCcccCCCCcccccccchH
Confidence            1111112223445555544442210000                      0001112322111000    0001123567


Q NP_000836.2     403 QFVIDAVYSMAYALHNMHKDLCPG---YIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQIT  479 (908)
Q Consensus       403 ~~~yDAv~~la~Al~~~~~~~~~~---~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~  479 (908)
                      .++||||+++++|++++....+..   ....|.......+..+.+.|++.+|.|.+|+.|+||++|+|...+.|++++..
T Consensus       445 ~~~yDaV~~~a~al~~~~~~~~~~~~~~~~~c~~~~~~~~~~l~~~l~~~~f~G~tG~~v~fd~~g~r~~~~~I~~~~~~  524 (568)
T 5FBK_A          445 YNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLS  524 (568)
T ss_dssp             HHHHHHHHHHHHHHHHHHTCCTTSSSSGGGCCCCGGGCCHHHHHHHHHTCEEECTTSCEEECCTTSCCCCCEEEEEEEEC
T ss_pred             HHHHHHHHHHHHHHHHHHhcCCCCCCCCCCCcccccccCHHHHHHHHhcCeeecCCCCEEEeCCCCCCCccEEEEEEEEc
Confidence            899999999999999987543321   01223221122344577888888999988657999999999888999888743


Q NP_000836.2     480 N--KSTEYKVIGHWTNQL------HLKVEDMQWAHR  507 (908)
Q Consensus       480 ~--~~~~~~~Vg~~~~~~------~~~~~~i~w~~~  507 (908)
                      .  +...++.||.|+...      .++...+.|.++
T Consensus       525 ~~~~~~~~~~vg~~~~~~~~~~~l~~~~~~i~w~~g  560 (568)
T 5FBK_A          525 PEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGF  560 (568)
T ss_dssp             TTTCSEEEEEEEEECTTSCTTSSEEECGGGCCBTTT
T ss_pred             CCCCcEEEEEEEEEEccccCCCeEEEeccceeecCC
Confidence            1  112588999998652      122335777654


No 32
>5FBK_B Extracellular calcium-sensing receptor; membrane protein, G-protein coupled receptor; HET: TCR, NAG, CSO; 2.1A {Homo sapiens}
Probab=99.81  E-value=4.7e-25  Score=251.32  Aligned_cols=460  Identities=32%  Similarity=0.552  Sum_probs=272.9  Template_Neff=10.500

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGE----------RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD  109 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~----------~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~  109 (908)
                      ....++++||+++|.++...          ....|+... ..+.....|++.|++++|+++++++|+++++++.|+++++
T Consensus        53 ~~~~~~i~Ig~l~p~~~~~~~~~~~~~~~~~~~~c~~~~-~~~~~~~~~~~~a~~~in~~~~~~~g~~i~~~~~D~~~~~  131 (568)
T 5FBK_B           53 AQKKGDIILGGLFPIHFGVAAKDQDLKSRPESVECIRYN-FRGFRWLQAMIFAIEEINSSPALLPNLTLGYRIFDTCNTV  131 (568)
T ss_dssp             EEECCSEEEEEEECSEEEECCCCCCCSSCCCCCCEEEEC-HHHHHHHHHHHHHHHHHHTCSSSSSSCCEEEEEEECTTCH
T ss_pred             eeecCCEEEEEEeeeeecccccCCCccCCCCcccceecc-cchHHHHHHHHHHHHHHhcCCCCCCCCEEeEEEEeCCCCH
Confidence            45678999999999986431          123455422 2456788999999999999888888899999999988775


Q NP_000836.2     110 TYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRY  189 (908)
Q Consensus       110 ~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~  189 (908)
                      ..+.+.+.+++.+-    +.+.....+.+.+....++++++||+.++..+..++.++...++|+|++.+..+.+.+...+
T Consensus       132 ~~a~~~~~~l~~~~----~~~~~~~~~~~~~~~~~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~  207 (568)
T 5FBK_B          132 SKALEATLSFVAQN----KIDSLNLDEFCNCSEHIPSTIAVVGATGSGVSTAVANLLGLFYIPQVSYASSSRLLSNKNQF  207 (568)
T ss_dssp             HHHHHHHHHHTHHH----HHCC---------------EEEEECCSSHHHHHHHHHHHGGGTCCEEESSCCCGGGGCTTTC
T ss_pred             HHHHHHHHHHHHhc----CcccCCccccccCCCCCCCeEEEEcCCCcHHHHHHHHHHhhhCCcEeccccCCcccCCcccC
Confidence            54443333333210    00000000000011111357899998888777788888999999999988766555443357


Q NP_000836.2     190 DFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRL  269 (908)
Q Consensus       190 ~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l  269 (908)
                      ++++++.+++...+.++++++++++|++|++++.++.++....+.+++.+++. ++++.....+.......++...++++
T Consensus       208 ~~~~~~~~~~~~~~~a~~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-gi~v~~~~~~~~~~~~~~~~~~~~~l  286 (568)
T 5FBK_B          208 KSFLRTIPNDEHQATAMADIIEYFRWNWVGTIAADDDYGRPGIEKFREEAEER-DICIDFSELISQYSDEEEIQHVVEVI  286 (568)
T ss_dssp             TTEEESSCCHHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHT-TCEEEEEEEECTTCCHHHHHHHHHHH
T ss_pred             CceeecCCCcHHHHHHHHHHHHHcCCeEEEEEEeCCccchhHHHHHHHHHHHC-CeEEEEEEeecCCCCHHHHHHHHHHH
Confidence            88999999998889999999988999999999977778888888888888775 46665433222101223455667777


Q NP_000836.2     270 LETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPV-YQQEEIAEGAVTILPKRASIDGFDRYFRSR  348 (908)
Q Consensus       270 ~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~-~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~  348 (908)
                      +. .++|+|++.+....+..+++++++.|+.. ..|+..+.|....... ........+.+.+.........|..|....
T Consensus       287 ~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~i~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~f~~~~~~~  364 (568)
T 5FBK_B          287 QN-STAKVIVVFSSGPDLEPLIKEIVRRNITG-KIWLASEAWASSSLIAMPQYFHVVGGTIGFALKAGQIPGFREFLKKV  364 (568)
T ss_dssp             HH-CCCCEEEEECCHHHHHHHHHHHHHTTCCC-CEEEECHHHHTCTTTCCGGGHHHHTTCEEEEECCBCCTTHHHHHHTC
T ss_pred             Hh-CCCeEEEEecCchhHHHHHHHHHHcCCCC-CEEEEechhcccccccCccceeeeccEEEEEecCCcCchHHHHHHhc
Confidence            63 57899888877777888999988888753 4566655443321100 000111223333322222233333332221


Q NP_000836.2     349 TLANNRRNVWFAEFWEENFGCKLGSHGK----------------------RNSHIKKCTGLERIAR----DSSYEQEGKV  402 (908)
Q Consensus       349 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------------------~~~~~~~c~~~~~~~~----~~~~~~~~~~  402 (908)
                      .+.......++.++|++.+.|.......                      ...+...|+..+....    ........++
T Consensus       365 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~a  444 (568)
T 5FBK_B          365 HPRKSVHNGFAKEFWEETFNCHLQEGAKGPLPVDTFLRGHEESGDRFSNSSTAFRPLCTGDENISSVETPYIDYTHLRIS  444 (568)
T ss_dssp             CTTTCSSBTTHHHHHHHHHTCBCC-----------------------------CCCBCCSCCCGGGSCCTTTCCSCBSHH
T ss_pred             CCccCCCChhHHHHHHHHhCCccCCCCCCCCCchhcccCCcccCCccCCCCCCCCCCCCCCCCcccCCCCcccccccchH
Confidence            1111112223445555544442210000                      0001112322111000    0001123567


Q NP_000836.2     403 QFVIDAVYSMAYALHNMHKDLCPG---YIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQIT  479 (908)
Q Consensus       403 ~~~yDAv~~la~Al~~~~~~~~~~---~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~  479 (908)
                      .++||||+++++|++++....+..   ....|.......+..+.+.|++.+|.|.+|+.|+||++|+|...+.|++++..
T Consensus       445 ~~~yDaV~~~a~al~~~~~~~~~~~~~~~~~c~~~~~~~~~~l~~~l~~~~f~G~tG~~v~f~~~G~r~~~~~I~~~~~~  524 (568)
T 5FBK_B          445 YNVYLAVYSIAHALQDIYTCLPGRGLFTNGSCADIKKVEAWQVLKHLRHLNFTNNMGEQVTFDECGDLVGNYSIINWHLS  524 (568)
T ss_dssp             HHHHHHHHHHHHHHHHHHTCCTTSSSSGGGCCCCGGGCCHHHHHHHHHTCCEECTTSCEECCCTTSCCCCCEEEEEEEEC
T ss_pred             HHHHHHHHHHHHHHHHHHhcCCCCCCCCCCCcccccccCHHHHHHHHhhCeeecCCCCEEEeCCCCCCCCcEEEEEEEEc
Confidence            899999999999999987543321   01223221122344577888888999988757999999999888999888743


Q NP_000836.2     480 N--KSTEYKVIGHWTNQL------HLKVEDMQWAHR  507 (908)
Q Consensus       480 ~--~~~~~~~Vg~~~~~~------~~~~~~i~w~~~  507 (908)
                      .  +...++.||.|+...      .++...+.|.++
T Consensus       525 ~~~~~~~~~~vg~~~~~~~~~~~l~~~~~~i~W~~g  560 (568)
T 5FBK_B          525 PEDGSIVFKEVGYYNVYAKKGERLFINEEKILWSGF  560 (568)
T ss_dssp             TTTSSEEEEEEEEECTTSCTTSSEEECGGGCCCC--
T ss_pred             CCCCcEEEEEEEEEEeeccCCCeEEEeccceeccCC
Confidence            1  112588999998652      122335778654


No 33
>1DP4_A ATRIAL NATRIURETIC PEPTIDE RECEPTOR A; periplasmic binding protein fold, dimer; HET: SO4, NAG; 2.0A {Rattus norvegicus} SCOP: c.93.1.1
Probab=99.79  E-value=2.8e-24  Score=236.57  Aligned_cols=369  Identities=15%  Similarity=0.224  Sum_probs=238.8  Template_Neff=11.700

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-----SRDTYALEQSLT  118 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-----~~~~~a~~~~~~  118 (908)
                      ++++||+++|.++...         ...+.....|+++|++++|+++++++|+++++++.|+.     +++..+.+.+  
T Consensus         1 ~~i~ig~~~p~~~~~~---------~~~~~~~~~~~~~A~~~in~~~~~~~~~~i~l~~~d~~~~~~~~~~~~~~~~~--   69 (435)
T 1DP4_A            1 SDLTVAVVLPLTNTSY---------PWSWARVGPAVELALARVKARPDLLPGWTVRMVLGSSENAAGVCSDTAAPLAA--   69 (435)
T ss_dssp             CEEEEEEEECSSCCCS---------TTCHHHHHHHHHHHHHHHHTCTTSSTTCEEEEEEEECBCTTSSBCTTHHHHHH--
T ss_pred             CCeEEEEEcccCCCCC---------CcchhhhHHHHHHHHHHHHcCCCCCCCcEEEEEEcCCccccccccccchHHHH--
Confidence            3689999999987431         01266788999999999999887777899999988875     4433322222  


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                        .+++.                  .++++++||+.++..+..++.++...++|+|++.+.++.+.++..+++++++.|+
T Consensus        70 --~~~~~------------------~~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~~~p~  129 (435)
T 1DP4_A           70 --VDLKW------------------EHSPAVFLGPGCVYSAAPVGRFTAHWRVPLLTAGAPALGIGVKDEYALTTRTGPS  129 (435)
T ss_dssp             --HHHHH------------------HHCCSEEECCCSHHHHHHHHHHHHHHTCCEEESCCCCGGGGCTTTSTTEEECSCC
T ss_pred             --HHHHH------------------hcCCCEEECCCCcccchhHHHHHhhcCCCEEecCCchhccCccceeeeeeeeCCC
Confidence              22222                  1578899999888777888899999999999988877666544457899999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGES-----GVEAFTQISRE-IGGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~-----~~~~~~~~~~~-~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      ....+.++++++++++|+++++|+.++.++..     ..+.+.+.+++ . ++++.....+.  .+..++...+++++. 
T Consensus       130 ~~~~~~a~~~~~~~~~~~~v~ii~~~~~~g~~~~~~~~~~~~~~~~~~~~-~~~v~~~~~~~--~~~~~~~~~~~~~~~-  205 (435)
T 1DP4_A          130 HVKLGDFVTALHRRLGWEHQALVLYADRLGDDRPCFFIVEGLYMRVRERL-NITVNHQEFVE--GDPDHYPKLLRAVRR-  205 (435)
T ss_dssp             HHHHHHHHHHHHHHHTCCSEEEEEEECCSSSCCHHHHHHHHHHHHHHHHH-CCEEEEEEECT--TCGGGHHHHHHHHHH-
T ss_pred             HHHHHHHHHHHHHHHCCeEEEEEEEcCCCCCCceehHHHHHHHHHHHHHc-CCeeceeeecC--CCcchHHHHHHHHHh-
Confidence            99899999999988999999999876665533     45666666654 3 35554332222  122345566666652 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAP----------V------YQQEEIAEGAVTILPKR  335 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~----------~------~~~~~~~~g~~~~~~~~  335 (908)
                       ++++|++......+..+++++++.|+.. .+.|+..+.+......          .      ........+.+.+....
T Consensus       206 -~~~~iv~~~~~~~~~~~l~~a~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  284 (435)
T 1DP4_A          206 -KGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKSAQGLVPQKPWERGDGQDRSARQAFQAAKIITYKE  284 (435)
T ss_dssp             -HCSEEEEESCHHHHHHHHHHHHHTTCCTTTCEEEEECTTCTTSCSSCTTSCBCTTCCSSSCHHHHHHHGGGEEEEEECC
T ss_pred             -cccEEEEeCCHHHHHHHHHHHHHCCCCCCCEEEEEEEcCCcccccccCCCCCCCCcCCCCCCHHHHHHHHhceecccCC
Confidence             5788888877778889999999888853 4677765533221000          0      00000111111110000


Q NP_000836.2     336 ASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYA  415 (908)
Q Consensus       336 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~A  415 (908)
                                     ...+....|.+.+++.+...+           .|...       ...+..++..+|||+++++.|
T Consensus       285 ---------------~~~~~~~~f~~~~~~~~~~~~-----------~~~~~-------~~~~~~~~~~~yda~~~~~~a  331 (435)
T 1DP4_A          285 ---------------PDNPEYLEFLKQLKLLADKKF-----------NFTVE-------DGLKNIIPASFHDGLLLYVQA  331 (435)
T ss_dssp             ---------------CCSHHHHHHHHHHHHHHHHHH-----------CCCCC-------CSGGGHHHHHHHHHHHHHHHH
T ss_pred             ---------------CCCHHHHHHHHHHHHHhhcCC-----------CCCcc-------cccccccHHHHHHHHHHHHHH
Confidence                           000111112222222111000           01000       012345678899999999999


Q NP_000836.2     416 LHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       416 l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ++++....+.          ..++..+.+.|++..|.|.+| .+.|+++|++...+.+.+++..  .+.++.||.|+..
T Consensus       332 l~~~~~~~~~----------~~~~~~l~~~l~~~~f~g~~G-~~~f~~~g~~~~~~~i~~~~~~--~~~~~~vg~~~~~  397 (435)
T 1DP4_A          332 VTETLAQGGT----------VTDGENITQRMWNRSFQGVTG-YLKIDRNGDRDTDFSLWDMDPE--TGAFRVVLNYNGT  397 (435)
T ss_dssp             HHHHHHTTCC----------TTCHHHHHHTTTTEEEEETTE-EEEECTTSBBCCCEEEEEECTT--TCCEEEEEEECTT
T ss_pred             HHHHHHcCCC----------CCCHHHHHHHHhcceEeecCe-eEEECCCCCccccEEEEEEcCC--CCeEEEEEEEecC
Confidence            9988643210          124456778888889999999 8999999998877888888742  2468899999865


No 34
>1DP4_C ATRIAL NATRIURETIC PEPTIDE RECEPTOR A; periplasmic binding protein fold, dimer; HET: NAG, SO4; 2.0A {Rattus norvegicus} SCOP: c.93.1.1
Probab=99.79  E-value=2.8e-24  Score=236.57  Aligned_cols=369  Identities=15%  Similarity=0.224  Sum_probs=238.8  Template_Neff=11.700

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-----SRDTYALEQSLT  118 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-----~~~~~a~~~~~~  118 (908)
                      ++++||+++|.++...         ...+.....|+++|++++|+++++++|+++++++.|+.     +++..+.+.+  
T Consensus         1 ~~i~ig~~~p~~~~~~---------~~~~~~~~~~~~~A~~~in~~~~~~~~~~i~l~~~d~~~~~~~~~~~~~~~~~--   69 (435)
T 1DP4_C            1 SDLTVAVVLPLTNTSY---------PWSWARVGPAVELALARVKARPDLLPGWTVRMVLGSSENAAGVCSDTAAPLAA--   69 (435)
T ss_dssp             CEEEEEEEECSSCCCS---------TTCHHHHHHHHHHHHHHHHTCTTSSTTCEEEEEEEECBCTTSSBCTTHHHHHH--
T ss_pred             CCeEEEEEcccCCCCC---------CcchhhhHHHHHHHHHHHHcCCCCCCCcEEEEEEcCCccccccccccchHHHH--
Confidence            3689999999987431         01266788999999999999887777899999988875     4433322222  


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                        .+++.                  .++++++||+.++..+..++.++...++|+|++.+.++.+.++..+++++++.|+
T Consensus        70 --~~~~~------------------~~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~~~p~  129 (435)
T 1DP4_C           70 --VDLKW------------------EHSPAVFLGPGCVYSAAPVGRFTAHWRVPLLTAGAPALGIGVKDEYALTTRTGPS  129 (435)
T ss_dssp             --HHHHH------------------HHCCSEEECCCSHHHHHHHHHHHHHHTCCEEESCCCCGGGGCTTTSTTEEECSCC
T ss_pred             --HHHHH------------------hcCCCEEECCCCcccchhHHHHHhhcCCCEEecCCchhccCccceeeeeeeeCCC
Confidence              22222                  1578899999888777888899999999999988877666544457899999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGES-----GVEAFTQISRE-IGGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~-----~~~~~~~~~~~-~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      ....+.++++++++++|+++++|+.++.++..     ..+.+.+.+++ . ++++.....+.  .+..++...+++++. 
T Consensus       130 ~~~~~~a~~~~~~~~~~~~v~ii~~~~~~g~~~~~~~~~~~~~~~~~~~~-~~~v~~~~~~~--~~~~~~~~~~~~~~~-  205 (435)
T 1DP4_C          130 HVKLGDFVTALHRRLGWEHQALVLYADRLGDDRPCFFIVEGLYMRVRERL-NITVNHQEFVE--GDPDHYPKLLRAVRR-  205 (435)
T ss_dssp             HHHHHHHHHHHHHHHTCCSEEEEEEECCSSSCCHHHHHHHHHHHHHHHHH-CCEEEEEEECT--TCGGGHHHHHHHHHH-
T ss_pred             HHHHHHHHHHHHHHHCCeEEEEEEEcCCCCCCceehHHHHHHHHHHHHHc-CCeeceeeecC--CCcchHHHHHHHHHh-
Confidence            99899999999988999999999876665533     45666666654 3 35554332222  122345566666652 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAP----------V------YQQEEIAEGAVTILPKR  335 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~----------~------~~~~~~~~g~~~~~~~~  335 (908)
                       ++++|++......+..+++++++.|+.. .+.|+..+.+......          .      ........+.+.+....
T Consensus       206 -~~~~iv~~~~~~~~~~~l~~a~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  284 (435)
T 1DP4_C          206 -KGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKSAQGLVPQKPWERGDGQDRSARQAFQAAKIITYKE  284 (435)
T ss_dssp             -HCSEEEEESCHHHHHHHHHHHHHTTCCTTTCEEEEECTTCTTSCSSCTTSCBCTTCCSSSCHHHHHHHGGGEEEEEECC
T ss_pred             -cccEEEEeCCHHHHHHHHHHHHHCCCCCCCEEEEEEEcCCcccccccCCCCCCCCcCCCCCCHHHHHHHHhceecccCC
Confidence             5788888877778889999999888853 4677765533221000          0      00000111111110000


Q NP_000836.2     336 ASIDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYA  415 (908)
Q Consensus       336 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~A  415 (908)
                                     ...+....|.+.+++.+...+           .|...       ...+..++..+|||+++++.|
T Consensus       285 ---------------~~~~~~~~f~~~~~~~~~~~~-----------~~~~~-------~~~~~~~~~~~yda~~~~~~a  331 (435)
T 1DP4_C          285 ---------------PDNPEYLEFLKQLKLLADKKF-----------NFTVE-------DGLKNIIPASFHDGLLLYVQA  331 (435)
T ss_dssp             ---------------CCSHHHHHHHHHHHHHHHHHH-----------CCCCC-------CSGGGHHHHHHHHHHHHHHHH
T ss_pred             ---------------CCCHHHHHHHHHHHHHhhcCC-----------CCCcc-------cccccccHHHHHHHHHHHHHH
Confidence                           000111112222222111000           01000       012345678899999999999


Q NP_000836.2     416 LHNMHKDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       416 l~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ++++....+.          ..++..+.+.|++..|.|.+| .+.|+++|++...+.+.+++..  .+.++.||.|+..
T Consensus       332 l~~~~~~~~~----------~~~~~~l~~~l~~~~f~g~~G-~~~f~~~g~~~~~~~i~~~~~~--~~~~~~vg~~~~~  397 (435)
T 1DP4_C          332 VTETLAQGGT----------VTDGENITQRMWNRSFQGVTG-YLKIDRNGDRDTDFSLWDMDPE--TGAFRVVLNYNGT  397 (435)
T ss_dssp             HHHHHHTTCC----------TTCHHHHHHTTTTEEEEETTE-EEEECTTSBBCCCEEEEEECTT--TCCEEEEEEECTT
T ss_pred             HHHHHHcCCC----------CCCHHHHHHHHhcceEeecCe-eEEECCCCCccccEEEEEEcCC--CCeEEEEEEEecC
Confidence            9988643210          124456778888889999999 8999999998877888888742  2468899999865


No 35
>5X2M_A Taste receptor, type 1, member; receptor, ligand binding, amino acid; HET: GLN, NAG; 2.206A {Oryzias latipes}
Probab=99.78  E-value=4.3e-24  Score=237.04  Aligned_cols=419  Identities=24%  Similarity=0.397  Sum_probs=256.0  Template_Neff=11.300

Q NP_000836.2      35 EYAHSIRVDGDIILGGLFPVHAKGE------RGVPCGE-LKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCS  107 (908)
Q Consensus        35 ~~~~~~~~~~~i~Ig~l~p~~~~~~------~~~~c~~-~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~  107 (908)
                      ..+.....+++++||+++|+++...      ....|+. .....+.....|+++|++++|+++++++|+++++.+.|++.
T Consensus         4 ~~~~~~~~~~~i~ig~l~p~~~~~~~~~~~~~~~~c~~~~~~~~g~~~~~a~~~A~~~iN~~~~~~~~~~i~~~~~d~~~   83 (461)
T 5X2M_A            4 DQTSEFHLRGDYLIGGLFNIHYVAAANFQRPQAIDCSSKLFILPNYRRFQMMRFSVEEINNSSSLLPNVSLGYQMFDHCS   83 (461)
T ss_dssp             --CBTTEECCSEEEEEEECCEECCCCCCSSCBCCCGGGSEECHHHHHHHHHHHHHHHHHHTCSSSSTTCCEEEEEEECSC
T ss_pred             ccceeeEecCCEEEEeEEEeeecccccCCCCCCcccccceecchhHHHHHHHHHHHHHHHcCCCCCCCCcceEEEEcCCC
Confidence            3455678889999999999997632      1234553 11235667889999999999998878788999999999876


Q NP_000836.2     108 RDTYALEQ-SLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN  186 (908)
Q Consensus       108 ~~~~a~~~-~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~  186 (908)
                      +...+... .....++++..          ...+....++++++||+.++.....++.++...++|+|++.+..+.+.+.
T Consensus        84 ~~~~~~~~~~~~~~~~l~~~----------~~~~~~~~~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~  153 (461)
T 5X2M_A           84 DIHSFPGIFKLLSVNDLIRP----------WEDASTGLPNAIGVVGPFTSTHALSIAPIFMTNLFPMVSYGCSGSVFSKE  153 (461)
T ss_dssp             STTCHHHHHHHHCSSSEECT----------TCC----CCSCSEEECCSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCT
T ss_pred             CcchHHHHHHHHhcCCcCCc----------ccccCCCCCCeeEEECCCCcHHHHHHHHHHhhcCCCeecceecCcccCCc
Confidence            54321110 01111222110          00000001478899999888777788888999999999988766555443


Q NP_000836.2     187 TRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKII  266 (908)
Q Consensus       187 ~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~  266 (908)
                      ..+++++++.++....+.++++++++++|+++++++.++.++....+.+++.+++. ++++.....++  . ..++...+
T Consensus       154 ~~~~~~~~~~~~~~~~~~a~~~~l~~~~~~~v~vi~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~-~~~~~~~~  229 (461)
T 5X2M_A          154 NLYPSFLRTVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDS-EICLAFYKAIN--V-NTDYLQVF  229 (461)
T ss_dssp             TTSTTEEESSCCHHHHHHHHHHHHHHSSBCEEEEEEESSHHHHHHHHHHHHHHTTS-SCEEEEEEEEC--T-TCCHHHHH
T ss_pred             ccCCceeeecCCCHHHHHHHHHHHHHcCCcEEEEEEeCChhhHHHHHHHHHHHHhc-CcEEEEEEeeC--C-CccHHHHH
Confidence            35788999999999999999999988999999999987778888888888887775 46665433332  1 23466677


Q NP_000836.2     267 KRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVY-QQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       267 ~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~-~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      ++++. .++++|++......+..+++++++.|+. .+.|+..+.|........ .......+.+.+.......+.+..++
T Consensus       230 ~~i~~-~~~~~iv~~~~~~~~~~~l~~~~~~g~~-~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  307 (461)
T 5X2M_A          230 KQIEE-QNIKVIVVFAPKVYAEAVVESAVQLNVT-NKVWIADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFI  307 (461)
T ss_dssp             HHHHH-TTCCEEEEECCHHHHHHHHHHHHHTTCC-SEEEEECTTTTTCSSGGGSTTGGGGEEEEEEECCCCCCTTHHHHH
T ss_pred             HHHHh-CCCeEEEEECChHHHHHHHHHHHHcCCC-CcEEEEechhhcCCccccCCccceeccEEEEeccceeCCCHHHHH
Confidence            77763 5789988887777788999999988875 356666554432211000 00011122222211111111122111


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      ............+..++++..+.|.               .... .. .......++..+|||++++++|++++..+.. 
T Consensus       308 ~~~~~~~~~~~~~~~~~~~~~~~~~---------------~~~~-~~-~~~~~~~~~~~~yDav~~~a~a~~~~~~~~~-  369 (461)
T 5X2M_A          308 YSAISQTDGGDTEQKMFCNQKCNCS---------------NLSV-KS-LLNADPSFSFPVYAAVYAIAHALHNTLRCGS-  369 (461)
T ss_dssp             HHHHTC---------CCTTCCCCCT---------------TCCH-HH-HHTSCCTTHHHHHHHHHHHHHHHHHHHTCCS-
T ss_pred             HhcccccCCCChhHHHHhcccCCCC---------------cccc-hh-hccCCCccHHHHHHHHHHHHHHHHHHhhcCC-
Confidence            1000000000111111111111110               0000 00 0011234678899999999999998864321 


Q NP_000836.2     426 GYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       426 ~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                         ..|......++..+.+.|++..|.|.+| .+.|+++|++. ..+.+++++.   ++.++.||.|+..
T Consensus       370 ---~~~~~~~~~~~~~l~~~l~~~~f~g~~G-~i~f~~~g~~~~~~~~i~~~~~---~~~~~~vg~~~~~  432 (461)
T 5X2M_A          370 ---DRCPKNITVHPHMILEELKKSNFTLLNQ-TVQFDENGDPKFGSLSVVFWNS---SGNAEEVGSYHFQ  432 (461)
T ss_dssp             ---SCCCCSCCCCHHHHHHHHHTCCEEETTE-EECBCTTSCBSCCCEEEEEECT---TSCEEEEEEECSS
T ss_pred             ---CCCCccCCCCHHHHHHHHhcCcEEeCCc-eEEECCCCCCCCccEEEEEEeC---CCCEEEEEEEEcC
Confidence               1121111234556778888889999988 89999999886 6788888873   2478899999865


No 36
>5X2N_C Taste receptor, type 1, member; receptor, ligand binding, amino acid; HET: ALA, NAG; 2.2A {Oryzias latipes}
Probab=99.78  E-value=4.3e-24  Score=237.04  Aligned_cols=419  Identities=24%  Similarity=0.397  Sum_probs=256.5  Template_Neff=11.300

Q NP_000836.2      35 EYAHSIRVDGDIILGGLFPVHAKGE------RGVPCGE-LKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCS  107 (908)
Q Consensus        35 ~~~~~~~~~~~i~Ig~l~p~~~~~~------~~~~c~~-~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~  107 (908)
                      ..+.....+++++||+++|+++...      ....|+. .....+.....|+++|++++|+++++++|+++++.+.|++.
T Consensus         4 ~~~~~~~~~~~i~ig~l~p~~~~~~~~~~~~~~~~c~~~~~~~~g~~~~~a~~~A~~~iN~~~~~~~~~~i~~~~~d~~~   83 (461)
T 5X2N_C            4 DQTSEFHLRGDYLIGGLFNIHYVAAANFQRPQAIDCSSKLFILPNYRRFQMMRFSVEEINNSSSLLPNVSLGYQMFDHCS   83 (461)
T ss_dssp             --CCTTEECCSEEEEEEECCEECCCCCCSSSBCCCGGGSEECHHHHHHHHHHHHHHHHHHHCSSSSTTCCEEEEEEECSC
T ss_pred             ccceeeEecCCEEEEeEEEeeecccccCCCCCCcccccceecchhHHHHHHHHHHHHHHHcCCCCCCCCcceEEEEcCCC
Confidence            3455678889999999999997632      1234553 11235667889999999999998878788999999999876


Q NP_000836.2     108 RDTYALEQ-SLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN  186 (908)
Q Consensus       108 ~~~~a~~~-~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~  186 (908)
                      +...+... .....++++..          ...+....++++++||+.++.....++.++...++|+|++.+..+.+.+.
T Consensus        84 ~~~~~~~~~~~~~~~~l~~~----------~~~~~~~~~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~  153 (461)
T 5X2N_C           84 DIHSFPGIFKLLSVNDLIRP----------WEDASTGLPNAIGVVGPFTSTHALSIAPIFMTNLFPMVSYGCSGSVFSKE  153 (461)
T ss_dssp             GGGCHHHHHHHHCBTTEECT----------TCC-CCCCCSCSEEECCSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCT
T ss_pred             CcchHHHHHHHHhcCCcCCc----------ccccCCCCCCeeEEECCCCcHHHHHHHHHHhhcCCCeecceecCcccCCc
Confidence            54321110 01111222110          00000001478899999888777788888999999999988766555443


Q NP_000836.2     187 TRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKII  266 (908)
Q Consensus       187 ~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~  266 (908)
                      ..+++++++.++....+.++++++++++|+++++++.++.++....+.+++.+++. ++++.....++  . ..++...+
T Consensus       154 ~~~~~~~~~~~~~~~~~~a~~~~l~~~~~~~v~vi~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~-~~~~~~~~  229 (461)
T 5X2N_C          154 NLYPSFLRTVHSNKDVINAIVGIILNFNWRWVAFLYSDDDFGKDGLEQFKNKIEDS-EICLAFYKAIN--V-NTDYLQVF  229 (461)
T ss_dssp             TTCTTEEESSCCHHHHHHHHHHHHHTSSBCEEEEEEESSHHHHHHHHHHHHHHTTS-SCEEEEEEEEC--T-TCCHHHHH
T ss_pred             ccCCceeeecCCCHHHHHHHHHHHHHcCCcEEEEEEeCChhhHHHHHHHHHHHHhc-CcEEEEEEeeC--C-CccHHHHH
Confidence            35788999999999999999999988999999999987778888888888887775 46665433332  1 23466677


Q NP_000836.2     267 KRLLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVY-QQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       267 ~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~-~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      ++++. .++++|++......+..+++++++.|+. .+.|+..+.|........ .......+.+.+.......+.+..++
T Consensus       230 ~~i~~-~~~~~iv~~~~~~~~~~~l~~~~~~g~~-~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  307 (461)
T 5X2N_C          230 KQIEE-QNIKVIVVFAPKVYAEAVVESAVQLNVT-NKVWIADDGWSLNKKLPSMNGIQNIGTVLGVAQPVVTIPGFTDFI  307 (461)
T ss_dssp             HHHHH-TTCCEEEEECCHHHHHHHHHHHHHTTCC-SEEEEECTTTTTCSSGGGSTTGGGGEEEEEEECCCCCCTTHHHHH
T ss_pred             HHHHh-CCCeEEEEECChHHHHHHHHHHHHcCCC-CcEEEEechhhcCCccccCCccceeccEEEEeccceeCCCHHHHH
Confidence            77763 5789988887777788999999988875 356666554432211000 00011122222211111111122111


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      ............+..++++..+.|.               .... .. .......++..+|||++++++|++++..+.. 
T Consensus       308 ~~~~~~~~~~~~~~~~~~~~~~~~~---------------~~~~-~~-~~~~~~~~~~~~yDav~~~a~a~~~~~~~~~-  369 (461)
T 5X2N_C          308 YSAISQTDGGDTEQKMFCNQKCNCS---------------NLSV-KS-LLNADPSFSFPVYAAVYAIAHALHNTLRCGS-  369 (461)
T ss_dssp             HHHHCC-------CCCCTTCCCCCC---------------SCCH-HH-HHTSCCTTHHHHHHHHHHHHHHHHHHTTCCS-
T ss_pred             HhcccccCCCChhHHHHhcccCCCC---------------cccc-hh-hccCCCccHHHHHHHHHHHHHHHHHHhhcCC-
Confidence            1000000000111111111111110               0000 00 0011234678899999999999998864321 


Q NP_000836.2     426 GYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       426 ~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                         ..|......++..+.+.|++..|.|.+| .+.|+++|++. ..+.+++++.   ++.++.||.|+..
T Consensus       370 ---~~~~~~~~~~~~~l~~~l~~~~f~g~~G-~i~f~~~g~~~~~~~~i~~~~~---~~~~~~vg~~~~~  432 (461)
T 5X2N_C          370 ---DRCPKNITVHPHMILEELKKSNFTLLNQ-TVQFDENGDPKFGSLSVVFWNS---SGNAEEVGSYHFQ  432 (461)
T ss_dssp             ---SCCCSSCCCCHHHHHHHHHTCCEEETTE-EECBCTTSCBSCCCEEEEEECT---TSCEEEEEEECSS
T ss_pred             ---CCCCccCCCCHHHHHHHHhcCcEEeCCc-eEEECCCCCCCCccEEEEEEeC---CCCEEEEEEEEcC
Confidence               1121111234556778888889999988 89999999886 6788888873   2478899999865


No 37
>5X2M_B Taste receptor, type 1, member; receptor, ligand binding, amino acid; HET: GLN, NAG; 2.206A {Oryzias latipes}
Probab=99.76  E-value=1.5e-23  Score=233.83  Aligned_cols=440  Identities=23%  Similarity=0.419  Sum_probs=263.9  Template_Neff=11.200

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGE---------RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD  109 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~---------~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~  109 (908)
                      .....++++||+++|.++...         ....|+... ..+.....|+++|++++|+++++++|+++++++.|+++++
T Consensus        12 ~~~~~~~i~ig~l~p~~~~~~~~~~~~~~~~~~~c~~~~-~~~~~~~~a~~~a~~~~n~~~~~~~g~~i~~~~~d~~~~~   90 (478)
T 5X2M_B           12 LFSMPGDIKLGGLFPIKEQSNEVSNDLTKLNSVSCDSLN-KDGLGRALVMKYAVEEINANSQLLPGVKLGYKIYNTCRHS   90 (478)
T ss_dssp             SSEECCSEEEEEEECCEECC------------CCCCEEC-HHHHHHHHHHHHHHHHHHHCTTTSTTCCEEEEEEECTTCH
T ss_pred             ccccCCCEEEEEEEeccccCCcccccccccCCCcccccc-chhHHHHHHHHHHHHHHHcCCCCCCCCeeeEEEEccCCCH
Confidence            356678999999999987532         123465432 3467788999999999999888877899999999988775


Q NP_000836.2     110 TYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRY  189 (908)
Q Consensus       110 ~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~  189 (908)
                      ..+.+.+.+++.+.... ....     .+.....+++++++||+.++.....++.++...++|+|++....+.+.+...+
T Consensus        91 ~~~~~~~~~l~~~~~~~-~~~~-----~~~~~~~~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~  164 (478)
T 5X2M_B           91 AVIVRPALSFLTEKSNG-TLSV-----ECNYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLVY  164 (478)
T ss_dssp             HHHHHHHHHTTSBTTTS-SEEC-----CSBCTTCCBSCSEEECCSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCTTTS
T ss_pred             HHHHHHHHHHHhhccCC-cccc-----ccCCCCCCCCeEEEEcCCCHHHHHHHHHHHHhhCCcEeecCCCCcccCCCccc
Confidence            54433333333210000 0000     00000001578899998888777778888899999999988766655443357


Q NP_000836.2     190 DFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE-PRPGEFEKIIKR  268 (908)
Q Consensus       190 ~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~-~~~~~~~~~~~~  268 (908)
                      ++++++.++....+.++++++++++|++|++|+.++.++....+.+++.+++. ++++.....+... ....++...+++
T Consensus       165 ~~~~~~~~~~~~~~~al~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~  243 (478)
T 5X2M_B          165 PSFFRTVPSDIRQVDAMVQLIKKFNWNWVAVVGSEEEYGQQGVQQFSKKAEDM-GVCVAYQGLIPIYDDPKPAIQTIINN  243 (478)
T ss_dssp             TTEEESSCCHHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEECSSSCCHHHHHHHHHH
T ss_pred             cceeecCCCcHHHHHHHHHHHHHcCCeEEEEEecCCHHHHHHHHHHHHHHHHc-CcEEEEEeeecCCCCChHHHHHHHHH
Confidence            89999999998899999999988999999999987778888888888888765 4555433222210 112345566677


Q NP_000836.2     269 LLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQ-QEEIAEGAVTILPKRASIDGFDRYFRS  347 (908)
Q Consensus       269 l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~-~~~~~~g~~~~~~~~~~~~~~~~~~~~  347 (908)
                      ++. .++|+|++......+..+++++++.|+.  ..|++.+.|......... ......+.+.+.........+      
T Consensus       244 l~~-~~~~~ivl~~~~~~~~~~l~~~~~~g~~--~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~------  314 (478)
T 5X2M_B          244 IQT-TEVKVVVVFSLVSPAVSFFEEVIKKNLT--GVWIASSSWAISDKVYSLPNIDSIGTVIGFIDETETLELL------  314 (478)
T ss_dssp             HHH-HTCSEEEEECCHHHHHHHHHHHHHTTCC--EEEEECTTTTTCHHHHTSTTGGGSEEEEEEEECCCCCTTH------
T ss_pred             Hhc-CCCeEEEEEccChhHHHHHHHHHHcCCc--eeEEEecchhcccchhcCCCcccccceEEEEecccccccc------
Confidence            763 5788888877677788889999888874  356666544332110000 011112222211110000000      


Q NP_000836.2     348 RTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARD-----SSYEQEGKVQFVIDAVYSMAYALHNMHKD  422 (908)
Q Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~-----~~~~~~~~~~~~yDAv~~la~Al~~~~~~  422 (908)
                           .+....|.+.+.+.+......     .....|.........     .......++..+|||++++++|+++....
T Consensus       315 -----~~~~~~f~~~~~~~~~~~~~~-----~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ydav~~~a~al~~~~~~  384 (478)
T 5X2M_B          315 -----SPFTEVLFKKIHEASPTEKPE-----DPYNPCPECWSLSPANVSLVKEESVQRTAFSVYAAVYTVAHALHKLLEC  384 (478)
T ss_dssp             -----HHHHHHHHHHHHHTTTC-----------CCSCGGGGGCCGGGGHHHHSHHHHTTHHHHHHHHHHHHHHHHHHTTC
T ss_pred             -----cHHHHHHHHHHHHcCCCCCCC-----CCCCCCCCccccCCCCcccccccccchHHHHHHHHHHHHHHHHHHHhcC
Confidence                 000111111111111100000     000011110000000     00123456778999999999999988753


Q NP_000836.2     423 LCPGYIGLCPRM--STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQL-HLKV  499 (908)
Q Consensus       423 ~~~~~~~~~~~~--~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~-~~~~  499 (908)
                      .+.    .|...  ...+++.+.+.|++.+|.|.+| .+.||++|++...+.+++++..  ++.++.||.|+... .++.
T Consensus       385 ~~~----~c~~~~~~~~~~~~l~~~l~~~~~~g~~G-~v~fd~~g~~~~~~~i~~~~~~--~~~~~~vg~~~~~~l~~~~  457 (478)
T 5X2M_B          385 NSA----ACKWSSSTRLYPWKLLEVLKEFSVNISNT-SLKFDQNGNPNIGYSVIQRIWE--NQSLSSVGSYRSANLSINE  457 (478)
T ss_dssp             CSS----CCSCCTTCCCCHHHHHHHHTTCEEEETTE-EEEBCTTSCBSCCEEEEEEETT--TTEEEEEEEEETTEEEECG
T ss_pred             CCC----cCCcccccCCCHHHHHHHHHhCeEecCCC-eEEECCCCCCCCceEEEEEEeC--CCeeEEEEEEecccceEec
Confidence            321    12110  1134556778888888999888 8999999998888888887642  25789999998652 3333


Q NP_000836.2     500 EDMQWAHREHTHP  512 (908)
Q Consensus       500 ~~i~w~~~~~~~p  512 (908)
                      ..+.|.++...+|
T Consensus       458 ~~~~w~~~~~~~p  470 (478)
T 5X2M_B          458 TLFKWYTNNSEKP  470 (478)
T ss_dssp             GGCCCCSTTSSCC
T ss_pred             cceeeecCCCCCC
Confidence            4577875433344


No 38
>5X2N_B Taste receptor, type 1, member; receptor, ligand binding, amino acid; HET: ALA, NAG; 2.2A {Oryzias latipes}
Probab=99.76  E-value=1.5e-23  Score=233.83  Aligned_cols=440  Identities=23%  Similarity=0.419  Sum_probs=264.3  Template_Neff=11.200

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGE---------RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD  109 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~---------~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~  109 (908)
                      .....++++||+++|.++...         ....|+... ..+.....|+++|++++|+++++++|+++++++.|+++++
T Consensus        12 ~~~~~~~i~ig~l~p~~~~~~~~~~~~~~~~~~~c~~~~-~~~~~~~~a~~~a~~~~n~~~~~~~g~~i~~~~~d~~~~~   90 (478)
T 5X2N_B           12 LFSMPGDIKLGGLFPIKEQSNEVSNDLTKLNSVSCDSLN-KDGLGRALVMKYAVEEINANSQLLPGVKLGYKIYNTCRHS   90 (478)
T ss_dssp             SSEECCSEEEEEEECCEECCC-----------CCCCEEC-HHHHHHHHHHHHHHHHHHHCTTTSTTCCEEEEEEECTTCH
T ss_pred             ccccCCCEEEEEEEeccccCCcccccccccCCCcccccc-chhHHHHHHHHHHHHHHHcCCCCCCCCeeeEEEEccCCCH
Confidence            356678999999999987532         123465432 3467788999999999999888877899999999988775


Q NP_000836.2     110 TYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRY  189 (908)
Q Consensus       110 ~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~  189 (908)
                      ..+.+.+.+++.+.... ....     .+.....+++++++||+.++.....++.++...++|+|++....+.+.+...+
T Consensus        91 ~~~~~~~~~l~~~~~~~-~~~~-----~~~~~~~~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~  164 (478)
T 5X2N_B           91 AVIVRPALSFLTEKSNG-TLSV-----ECNYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLVY  164 (478)
T ss_dssp             HHHHHHHHHTTSBTTTS-SEEC-----CSBCTTCCBSCSEEECCSSHHHHHHHHHHHHHTTCCEEESSCCCGGGGCTTTS
T ss_pred             HHHHHHHHHHHhhccCC-cccc-----ccCCCCCCCCeEEEEcCCCHHHHHHHHHHHHhhCCcEeecCCCCcccCCCccc
Confidence            54433333333210000 0000     00000001578899998888777778888899999999988766655443357


Q NP_000836.2     190 DFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE-PRPGEFEKIIKR  268 (908)
Q Consensus       190 ~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~-~~~~~~~~~~~~  268 (908)
                      ++++++.++....+.++++++++++|++|++|+.++.++....+.+++.+++. ++++.....+... ....++...+++
T Consensus       165 ~~~~~~~~~~~~~~~al~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~  243 (478)
T 5X2N_B          165 PSFFRTVPSDIRQVDAMVQLIKKFNWNWVAVVGSEEEYGQQGVQQFSKKAEDM-GVCVAYQGLIPIYDDPKPAIQTIINN  243 (478)
T ss_dssp             TTEEESSCCHHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEECSSSCCHHHHHHHHHH
T ss_pred             cceeecCCCcHHHHHHHHHHHHHcCCeEEEEEecCCHHHHHHHHHHHHHHHHc-CcEEEEEeeecCCCCChHHHHHHHHH
Confidence            89999999998899999999988999999999987778888888888888765 4555433222210 112345566677


Q NP_000836.2     269 LLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQ-QEEIAEGAVTILPKRASIDGFDRYFRS  347 (908)
Q Consensus       269 l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~-~~~~~~g~~~~~~~~~~~~~~~~~~~~  347 (908)
                      ++. .++|+|++......+..+++++++.|+.  ..|++.+.|......... ......+.+.+.........+      
T Consensus       244 l~~-~~~~~ivl~~~~~~~~~~l~~~~~~g~~--~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~------  314 (478)
T 5X2N_B          244 IQT-TEVKVVVVFSLVSPAVSFFEEVIKKNLT--GVWIASSSWAISDKVYSLPNIDSIGTVIGFIDETETLELL------  314 (478)
T ss_dssp             HHH-HTCSEEEEECCHHHHHHHHHHHHHTTCC--EEEEECTTTTTCHHHHTSTTGGGSEEEEEEEECCCCCTTH------
T ss_pred             Hhc-CCCeEEEEEccChhHHHHHHHHHHcCCc--eeEEEecchhcccchhcCCCcccccceEEEEecccccccc------
Confidence            763 5788888877677788889999888874  356666544332110000 011112222211110000000      


Q NP_000836.2     348 RTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARD-----SSYEQEGKVQFVIDAVYSMAYALHNMHKD  422 (908)
Q Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~-----~~~~~~~~~~~~yDAv~~la~Al~~~~~~  422 (908)
                           .+....|.+.+.+.+......     .....|.........     .......++..+|||++++++|+++....
T Consensus       315 -----~~~~~~f~~~~~~~~~~~~~~-----~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ydav~~~a~al~~~~~~  384 (478)
T 5X2N_B          315 -----SPFTEVLFKKIHEASPTEKPE-----DPYNPCPECWSLSPANVSLVKEESVQRTAFSVYAAVYTVAHALHKLLEC  384 (478)
T ss_dssp             -----HHHHHHHHHHHHHHTTSCCC------CTTCSCGGGGGCCGGGTHHHHSHHHHTTHHHHHHHHHHHHHHHHHHTTC
T ss_pred             -----cHHHHHHHHHHHHcCCCCCCC-----CCCCCCCCccccCCCCcccccccccchHHHHHHHHHHHHHHHHHHHhcC
Confidence                 000111111111111100000     000011110000000     00123456778999999999999988753


Q NP_000836.2     423 LCPGYIGLCPRM--STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQL-HLKV  499 (908)
Q Consensus       423 ~~~~~~~~~~~~--~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~-~~~~  499 (908)
                      .+.    .|...  ...+++.+.+.|++.+|.|.+| .+.||++|++...+.+++++..  ++.++.||.|+... .++.
T Consensus       385 ~~~----~c~~~~~~~~~~~~l~~~l~~~~~~g~~G-~v~fd~~g~~~~~~~i~~~~~~--~~~~~~vg~~~~~~l~~~~  457 (478)
T 5X2N_B          385 NSA----ACKWSSSTRLYPWKLLEVLKEFSVNISNT-SLKFDQNGNPNIGYSVIQRIWE--NQSLSSVGSYRSANLSINE  457 (478)
T ss_dssp             CSS----CCSCCTTCCCCHHHHHHHHTTCEEEETTE-EEEBCTTSCBSCCEEEEEEETT--TTEEEEEEEEETTEEEECG
T ss_pred             CCC----cCCcccccCCCHHHHHHHHHhCeEecCCC-eEEECCCCCCCCceEEEEEEeC--CCeeEEEEEEecccceEec
Confidence            321    12110  1134556778888888999888 8999999998888888887642  25789999998652 3333


Q NP_000836.2     500 EDMQWAHREHTHP  512 (908)
Q Consensus       500 ~~i~w~~~~~~~p  512 (908)
                      ..+.|.++...+|
T Consensus       458 ~~~~w~~~~~~~p  470 (478)
T 5X2N_B          458 TLFKWYTNNSEKP  470 (478)
T ss_dssp             GGCCCCSTTSCCC
T ss_pred             cceeeecCCCCCC
Confidence            4577875433344


No 39
>5X2N_D Taste receptor, type 1, member; receptor, ligand binding, amino acid; HET: NAG, ALA; 2.2A {Oryzias latipes}
Probab=99.76  E-value=1.5e-23  Score=233.83  Aligned_cols=440  Identities=23%  Similarity=0.419  Sum_probs=260.0  Template_Neff=11.200

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGE---------RGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD  109 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~---------~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~  109 (908)
                      .....++++||+++|.++...         ....|+... ..+.....|+++|++++|+++++++|+++++++.|+++++
T Consensus        12 ~~~~~~~i~ig~l~p~~~~~~~~~~~~~~~~~~~c~~~~-~~~~~~~~a~~~a~~~~n~~~~~~~g~~i~~~~~d~~~~~   90 (478)
T 5X2N_D           12 LFSMPGDIKLGGLFPIKEQSNEVSNDLTKLNSVSCDSLN-KDGLGRALVMKYAVEEINANSQLLPGVKLGYKIYNTCRHS   90 (478)
T ss_dssp             SSEECCSEEEEEEECCEECCC---------CCCCCCEEC-HHHHHHHHHHHHHHHHHHHCTTSSTTCCEEEEEEECTTCH
T ss_pred             ccccCCCEEEEEEEeccccCCcccccccccCCCcccccc-chhHHHHHHHHHHHHHHHcCCCCCCCCeeeEEEEccCCCH
Confidence            356678999999999987532         123465432 3467788999999999999888877899999999988775


Q NP_000836.2     110 TYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRY  189 (908)
Q Consensus       110 ~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~  189 (908)
                      ..+.+.+.+++.+.... ....     .+.....+++++++||+.++.....++.++...++|+|++....+.+.+...+
T Consensus        91 ~~~~~~~~~l~~~~~~~-~~~~-----~~~~~~~~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~  164 (478)
T 5X2N_D           91 AVIVRPALSFLTEKSNG-TLSV-----ECNYTDYETDMVAVIGPQSSEMVTVIGKLLGFFLMPQISFGATSDKFSDSLVY  164 (478)
T ss_dssp             HHHHHHHHHTTSBTTTS-SEEC-----CSBCTTCCBSCSEEECCSCHHHHHHHHHHHHHTTCCEEESSCCCGGGGCTTTS
T ss_pred             HHHHHHHHHHHhhccCC-cccc-----ccCCCCCCCCeEEEEcCCCHHHHHHHHHHHHhhCCcEeecCCCCcccCCCccc
Confidence            54433333333210000 0000     00000001578899998888777778888899999999988766655443357


Q NP_000836.2     190 DFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE-PRPGEFEKIIKR  268 (908)
Q Consensus       190 ~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~-~~~~~~~~~~~~  268 (908)
                      ++++++.++....+.++++++++++|++|++|+.++.++....+.+++.+++. ++++.....+... ....++...+++
T Consensus       165 ~~~~~~~~~~~~~~~al~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~  243 (478)
T 5X2N_D          165 PSFFRTVPSDIRQVDAMVQLIKKFNWNWVAVVGSEEEYGQQGVQQFSKKAEDM-GVCVAYQGLIPIYDDPKPAIQTIINN  243 (478)
T ss_dssp             TTEEESSCCHHHHHHHHHHHHTTTTCCCEEEEEESSHHHHHHHHHHHHHHTTT-TCCEEEEEEECSSSCCHHHHHHHHHH
T ss_pred             cceeecCCCcHHHHHHHHHHHHHcCCeEEEEEecCCHHHHHHHHHHHHHHHHc-CcEEEEEeeecCCCCChHHHHHHHHH
Confidence            89999999998899999999988999999999987778888888888888765 4555433222210 112345566677


Q NP_000836.2     269 LLETPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQ-QEEIAEGAVTILPKRASIDGFDRYFRS  347 (908)
Q Consensus       269 l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~-~~~~~~g~~~~~~~~~~~~~~~~~~~~  347 (908)
                      ++. .++|+|++......+..+++++++.|+.  ..|++.+.|......... ......+.+.+.........+      
T Consensus       244 l~~-~~~~~ivl~~~~~~~~~~l~~~~~~g~~--~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~------  314 (478)
T 5X2N_D          244 IQT-TEVKVVVVFSLVSPAVSFFEEVIKKNLT--GVWIASSSWAISDKVYSLPNIDSIGTVIGFIDETETLELL------  314 (478)
T ss_dssp             HHC-----CEEEECCHHHHHHHHHHHHHTTCC--EEEEECHHHHTCHHHHTSTTGGGGEEEEEEEECCCCCTTH------
T ss_pred             Hhc-CCCeEEEEEccChhHHHHHHHHHHcCCc--eeEEEecchhcccchhcCCCcccccceEEEEecccccccc------
Confidence            763 5788888877677788889999888874  356666544332110000 011112222211110000000      


Q NP_000836.2     348 RTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARD-----SSYEQEGKVQFVIDAVYSMAYALHNMHKD  422 (908)
Q Consensus       348 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~-----~~~~~~~~~~~~yDAv~~la~Al~~~~~~  422 (908)
                           .+....|.+.+.+.+......     .....|.........     .......++..+|||++++++|+++....
T Consensus       315 -----~~~~~~f~~~~~~~~~~~~~~-----~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ydav~~~a~al~~~~~~  384 (478)
T 5X2N_D          315 -----SPFTEVLFKKIHEASPTEKPE-----DPYNPCPECWSLSPANVSLVKEESVQRTAFSVYAAVYTVAHALHKLLEC  384 (478)
T ss_dssp             -----HHHHHHHHHHHHTC------------CTTCSCGGGGGCCGGGTHHHHSHHHHTTHHHHHHHHHHHHHHHHHHTTC
T ss_pred             -----cHHHHHHHHHHHHcCCCCCCC-----CCCCCCCCccccCCCCcccccccccchHHHHHHHHHHHHHHHHHHHhcC
Confidence                 000111111111111100000     000011110000000     00123456778999999999999988753


Q NP_000836.2     423 LCPGYIGLCPRM--STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQL-HLKV  499 (908)
Q Consensus       423 ~~~~~~~~~~~~--~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~-~~~~  499 (908)
                      .+.    .|...  ...+++.+.+.|++.+|.|.+| .+.||++|++...+.+++++..  ++.++.||.|+... .++.
T Consensus       385 ~~~----~c~~~~~~~~~~~~l~~~l~~~~~~g~~G-~v~fd~~g~~~~~~~i~~~~~~--~~~~~~vg~~~~~~l~~~~  457 (478)
T 5X2N_D          385 NSA----ACKWSSSTRLYPWKLLEVLKEFSVNISNT-SLKFDQNGNPNIGYSVIQRIWE--NQSLSSVGSYRSANLSINE  457 (478)
T ss_dssp             CSS----CCSCCTTCCCCHHHHHHHHTTCEEEETTE-EEEBCTTSCBSCCEEEEEEETT--TTEEEEEEEEETTEEEECG
T ss_pred             CCC----cCCcccccCCCHHHHHHHHHhCeEecCCC-eEEECCCCCCCCceEEEEEEeC--CCeeEEEEEEecccceEec
Confidence            321    12110  1134556778888888999888 8999999998888888887642  25789999998652 3333


Q NP_000836.2     500 EDMQWAHREHTHP  512 (908)
Q Consensus       500 ~~i~w~~~~~~~p  512 (908)
                      ..+.|.++...+|
T Consensus       458 ~~~~w~~~~~~~p  470 (478)
T 5X2N_D          458 TLFKWYTNNSEKP  470 (478)
T ss_dssp             GGCCCTTSCC---
T ss_pred             cceeeecCCCCCC
Confidence            4577875433344


No 40
>1JDN_A ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR; Natriuretic peptide receptor, dimer, allosteric; HET: NDG, BMA, FUC, MAN, NAG; 2.9A {Homo sapiens} SCOP: c.93.1.1
Probab=99.76  E-value=2e-23  Score=230.14  Aligned_cols=372  Identities=17%  Similarity=0.238  Sum_probs=238.1  Template_Neff=11.600

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPD----LLSNITLGVRILDTCSRDTYALEQS  116 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~----il~g~~l~~~~~d~~~~~~~a~~~~  116 (908)
                      ...++++||+++|.++...          ..+.....|++.|++++|++++    +++|.++++.+.|+++++..    +
T Consensus         5 ~~~~~i~Igv~~p~~~~~~----------~~~~~~~~~~~~a~~~~n~~~g~~~~~~~~~~i~~~~~d~~~~~~~----~   70 (441)
T 1JDN_A            5 LPPQKIEVLVLLPQDDSYL----------FSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRA----L   70 (441)
T ss_dssp             --CCCEEEEEEECSCTTST----------TCHHHHHHHHHHHHHHHTC-------CCSSCCEEEEEEECTTSHHH----H
T ss_pred             CCCCeEEEEEEccCCCCCC----------CcHHHHHHHHHHHHHHHhccCCCCcCCCCCCEEEEEEecCCCChHH----H
Confidence            4567899999999987531          2456788999999999998764    35688899998888776432    2


Q NP_000836.2     117 LTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN-TRYDFFSRV  195 (908)
Q Consensus       117 ~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~-~~~~~~~~~  195 (908)
                      .+.++++...                ..++++++||+.++..+..++.++...++|+|++.+..+.+... ..+++++++
T Consensus        71 ~~~~~~l~~~----------------~~~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~  134 (441)
T 1JDN_A           71 FSLVDRVAAA----------------RGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRV  134 (441)
T ss_dssp             HHHHHHHHHT----------------TTCCCSEEECCCSHHHHHHHHHHHHHTTCCEEESCCCSGGGGCCSSTTTTEEEC
T ss_pred             HHHHHHHHHH----------------hCCCCCEEECCCCHHhHHHHHHHHhhcCCcEEEecccchhhccchhhcccceee
Confidence            2233322210                01578999998888777788888999999999988766655443 346889999


Q NP_000836.2     196 VPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESG---VEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~---~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      .++....++++++++++++|+++++++.++.++...   .+.+++.+++. ++++... .+.. .+..++...+++++. 
T Consensus       135 ~~~~~~~~~~~~~~l~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~~~~-g~~v~~~-~~~~-~~~~~~~~~~~~i~~-  210 (441)
T 1JDN_A          135 APAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEE-GLHTSIY-SFDE-TKDLDLEDIVRNIQA-  210 (441)
T ss_dssp             SCCTHHHHHHHHHHHHHTTCCEEEEEEECCSSSCHHHHHHHHHHHHHHHH-TCEEEEE-EECT-TSCCCHHHHHHHHHT-
T ss_pred             ccCHHHHHHHHHHHHHHcCCeEEEEEEeCCcccceeeEEhhHHHHHHHHc-CCeeEEE-eccC-CCCCCHHHHHHHHHh-
Confidence            999999999999999888999999999877766655   67777777765 4665532 2211 123456667777763 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSK-----IAPV-----YQQEEIAEGAVTILPKRASIDGF  341 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~-----~~~~-----~~~~~~~~g~~~~~~~~~~~~~~  341 (908)
                      . +++|++......+..+++++++.|+.. .+.|+..+.....     ....     ........+.+......      
T Consensus       211 ~-~~~vv~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~------  283 (441)
T 1JDN_A          211 S-ERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLR------  283 (441)
T ss_dssp             T-CSEEEEECCHHHHHHHHHHHHHTTCTTSSSEEEEECGGGCGGGCCSCCCCSSTTHHHHHHHGGGEEEEEECC------
T ss_pred             c-CcEEEEEcCHHHHHHHHHHHHHCCCCCCCEEEEEEeccCccccCCCCccCCCcCcHHHHHHHHHcchhcccC------
Confidence            3 788888777777888899998888754 3667665421110     0000     00000111111111000      


Q NP_000836.2     342 DRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHK  421 (908)
Q Consensus       342 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~  421 (908)
                               ...+....|.+.+++.+... .         ..|          ...+..++..+|||++++++|+++...
T Consensus       284 ---------~~~~~~~~f~~~~~~~~~~~-~---------~~~----------~~~~~~~~~~~yDav~~~~~a~~~~~~  334 (441)
T 1JDN_A          284 ---------TVKPEFEKFSMEVKSSVEKQ-G---------LNM----------EDYVNMFVEGFHDAILLYVLALHEVLR  334 (441)
T ss_dssp             ---------CCCHHHHHHHHHHHHHHHHT-T---------CCC----------SCSCCHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             ---------CCChhHHHHHHHHHHHHHhc-C---------CCc----------cccchhHHHHHHHHHHHHHHHHHHHHH
Confidence                     00011111222222111100 0         000          012345678899999999999999865


Q NP_000836.2     422 DLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       422 ~~~~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ..+.          ..++..+.+.|++..|.|.+| .+.|+++|++...+.+++++..+ ++.++.||.|+..
T Consensus       335 ~~~~----------~~~~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~i~~~~~~~-~g~~~~vg~~~~~  395 (441)
T 1JDN_A          335 AGYS----------KKDGGKIIQQTWNRTFEGIAG-QVSIDANGDRYGDFSVIAMTDVE-AGTQEVIGDYFGK  395 (441)
T ss_dssp             TTCC----------TTCHHHHHHHHSSEEEEETTE-EEEECTTSBBCCEEEEEEEEETT-TTEEEEEEEEETT
T ss_pred             cCCC----------CCCHHHHHHHhhcCeEeecce-eEEECCCCCccceEEEEEeecCC-CCeEEEEEEEECC
Confidence            3211          123456777888889999998 89999999887778888876321 3578899999864


No 41
>1JDP_A ATRIAL NATRIURETIC PEPTIDE CLEARANCE RECEPTOR; hormone-receptor complex, natriuretic peptide receptor; HET: NAG, NDG; 2.0A {Homo sapiens} SCOP: c.93.1.1
Probab=99.76  E-value=2e-23  Score=230.14  Aligned_cols=372  Identities=17%  Similarity=0.238  Sum_probs=239.1  Template_Neff=11.600

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPD----LLSNITLGVRILDTCSRDTYALEQS  116 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~----il~g~~l~~~~~d~~~~~~~a~~~~  116 (908)
                      ...++++||+++|.++...          ..+.....|++.|++++|++++    +++|.++++.+.|+++++..    +
T Consensus         5 ~~~~~i~Igv~~p~~~~~~----------~~~~~~~~~~~~a~~~~n~~~g~~~~~~~~~~i~~~~~d~~~~~~~----~   70 (441)
T 1JDP_A            5 LPPQKIEVLVLLPQDDSYL----------FSLTRVRPAIEYALRSVEGNGTGRRLLPPGTRFQVAYEDSDCGNRA----L   70 (441)
T ss_dssp             CCCCEEEEEEEECSSTTST----------TCHHHHHHHHHHHHHHHCC-----CCSCTTCEEEEEEEECTTSTHH----H
T ss_pred             CCCCeEEEEEEccCCCCCC----------CcHHHHHHHHHHHHHHHhccCCCCcCCCCCCEEEEEEecCCCChHH----H
Confidence            4567899999999987531          2456788999999999998764    35688899998888776432    2


Q NP_000836.2     117 LTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN-TRYDFFSRV  195 (908)
Q Consensus       117 ~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~-~~~~~~~~~  195 (908)
                      .+.++++...                ..++++++||+.++..+..++.++...++|+|++.+..+.+... ..+++++++
T Consensus        71 ~~~~~~l~~~----------------~~~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~  134 (441)
T 1JDP_A           71 FSLVDRVAAA----------------RGAKPDLILGPVCEYAAAPVARLASHWDLPMLSAGALAAGFQHKDSEYSHLTRV  134 (441)
T ss_dssp             HHHHHHHHHT----------------TTCCCSEEECCCSHHHHHHHHHHHHHHTCCEEESCCCSGGGGCTTTTTTTEEEC
T ss_pred             HHHHHHHHHH----------------hCCCCCEEECCCCHHhHHHHHHHHhhcCCcEEEecccchhhccchhhcccceee
Confidence            2233322210                01578999998888777788888999999999988766655443 346889999


Q NP_000836.2     196 VPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESG---VEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~---~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      .++....++++++++++++|+++++++.++.++...   .+.+++.+++. ++++... .+.. .+..++...+++++. 
T Consensus       135 ~~~~~~~~~~~~~~l~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~~~~-g~~v~~~-~~~~-~~~~~~~~~~~~i~~-  210 (441)
T 1JDP_A          135 APAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEE-GLHTSIY-SFDE-TKDLDLEDIVRNIQA-  210 (441)
T ss_dssp             SCCHHHHHHHHHHHHHHHTCCEEEEEEECCSSSCHHHHHHHHHHHHHHHH-TCEEEEE-EECT-TSCCCHHHHHHHHHH-
T ss_pred             ccCHHHHHHHHHHHHHHcCCeEEEEEEeCCcccceeeEEhhHHHHHHHHc-CCeeEEE-eccC-CCCCCHHHHHHHHHh-
Confidence            999999999999999888999999999877766655   67777777765 4665532 2211 123456667777763 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSK-----IAPV-----YQQEEIAEGAVTILPKRASIDGF  341 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~-----~~~~-----~~~~~~~~g~~~~~~~~~~~~~~  341 (908)
                      . +++|++......+..+++++++.|+.. .+.|+..+.....     ....     ........+.+......      
T Consensus       211 ~-~~~vv~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~------  283 (441)
T 1JDP_A          211 S-ERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSWKRGDKHDFEAKQAYSSLQTVTLLR------  283 (441)
T ss_dssp             H-CSEEEEESCHHHHHHHHHHHHHTTCTTTTCEEEEECSSCCCSTTTCTTCCSSTTHHHHHHHGGGEEEEEECC------
T ss_pred             c-CcEEEEEcCHHHHHHHHHHHHHCCCCCCCEEEEEEeccCccccCCCCccCCCcCcHHHHHHHHHcchhcccC------
Confidence            3 788888777777888899998888754 3667665421110     0000     00000111111111000      


Q NP_000836.2     342 DRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHK  421 (908)
Q Consensus       342 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~  421 (908)
                               ...+....|.+.+++.+... .         ..|          ...+..++..+|||++++++|+++...
T Consensus       284 ---------~~~~~~~~f~~~~~~~~~~~-~---------~~~----------~~~~~~~~~~~yDav~~~~~a~~~~~~  334 (441)
T 1JDP_A          284 ---------TVKPEFEKFSMEVKSSVEKQ-G---------LNM----------EDYVNMFVEGFHDAILLYVLALHEVLR  334 (441)
T ss_dssp             ---------CCCHHHHHHHHHHHHHHHTT-T---------CCC----------CSSCCHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             ---------CCChhHHHHHHHHHHHHHhc-C---------CCc----------cccchhHHHHHHHHHHHHHHHHHHHHH
Confidence                     00011111222222111100 0         000          012345678899999999999999865


Q NP_000836.2     422 DLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       422 ~~~~~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ..+.          ..++..+.+.|++..|.|.+| .+.|+++|++...+.+++++..+ ++.++.||.|+..
T Consensus       335 ~~~~----------~~~~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~i~~~~~~~-~g~~~~vg~~~~~  395 (441)
T 1JDP_A          335 AGYS----------KKDGGKIIQQTWNRTFEGIAG-QVSIDANGDRYGDFSVIAMTDVE-AGTQEVIGDYFGK  395 (441)
T ss_dssp             TTCC----------TTCHHHHHHHHSSEEEEETTE-EEEECTTSBBCCEEEEEEEEETT-TTEEEEEEEEETT
T ss_pred             cCCC----------CCCHHHHHHHhhcCeEeecce-eEEECCCCCccceEEEEEeecCC-CCeEEEEEEEECC
Confidence            3211          123456777888889999998 89999999887778888876321 3578899999864


No 42
>4F11_A Gamma-aminobutyric acid type B receptor; Venus flytrap module, G-protein coupled; 2.38A {Homo sapiens}
Probab=99.72  E-value=2e-22  Score=221.47  Aligned_cols=391  Identities=19%  Similarity=0.262  Sum_probs=245.4  Template_Neff=11.600

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||+++|.++....        ...+.....|++.|++++|+.++ ++|+++++++.|+++++..+.+    
T Consensus         8 ~~~~~~~i~ig~~~~~~~~~~~--------~~~~~~~~~~~~~a~~~~n~~~~-~~~~~i~l~~~d~~~~~~~~~~----   74 (433)
T 4F11_A            8 PPPSSPPLSIMGLMPLTKEVAK--------GSIGRGVLPAVELAIEQIRNESL-LRPYFLDLRLYDTECDNAKGLK----   74 (433)
T ss_dssp             ---CCCEEEEEEEECCCTTSTT--------HHHHHHHHHHHHHHHHHHHHTTT-TTTCEEEEEEEECTTCHHHHHH----
T ss_pred             CCCCCCCeEEEEEEecCCcccC--------CcccccHHHHHHHHHHHHHhccC-CCCceEEEEEEcCCCChhHHHH----
Confidence            3456789999999999864310        02456788999999999998764 5578899999998876544333    


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+.+++..                 .++++++||+.++..+..++.++...++|+|++.+..+.+.+...+++++++.++
T Consensus        75 ~~~~l~~~-----------------~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  137 (433)
T 4F11_A           75 AFYDAIKY-----------------GPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPS  137 (433)
T ss_dssp             HHHHHHHH-----------------SCCCSEEEECCSHHHHHHHHHTHHHHTCEEEESSCCCGGGGCTTTCTTEEESSCC
T ss_pred             HHHHHHHh-----------------CCCeEEEEcCCChhHHHHHHHHccccCCeEEEeccCCHHHcCCCCCCceeeeCCC
Confidence            33333320                 0368899998888777778888889999999988766655443357889999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ...++.++++++++++|+++++++.++.++....+.+++.+++. ++++.....+.     .++...+++++. .++++|
T Consensus       138 ~~~~~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~-----~~~~~~~~~~~~-~~~~~v  210 (433)
T 4F11_A          138 DNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGE-DIEISDTESFS-----NDPCTSVKKLKG-NDVRII  210 (433)
T ss_dssp             GGGHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHSSSS-SCEEEEEEEES-----SCCHHHHHHHHH-TTCCEE
T ss_pred             hhhhhHHHHHHHHHcCCCEEEEEEecchhhHHHHHHHHHHHhcC-CeEEEeeeeec-----CChhHHHHHHhc-CCcEEE
Confidence            98889999999988899999999987777777778888877765 46654332221     235556667763 578888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVY-------------QQEEIAEGAVTILPKRASIDGFDRY  344 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~-------------~~~~~~~g~~~~~~~~~~~~~~~~~  344 (908)
                      ++.........+++++++.|+.. ++.|+..+ +........             .......+.+.+.........+..+
T Consensus       211 ~~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~  289 (433)
T 4F11_A          211 LGQFDQNMAAKVFCCAYEENMYGSKYQWIIPG-WYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTI  289 (433)
T ss_dssp             EEECCHHHHHHHHHHHHHTTCCSTTCEEEEES-CSCTTTTTCC------CCSCHHHHHHHHTTCEEEEECSSCCCCCCCT
T ss_pred             EEeCCHHHHHHHHHHHHHcCCcCCCeEEEccC-CcCcchhHHhhccccCCCccHHHHHHHHccceeeEeecCCCCCcccc
Confidence            77766667788899988888753 45666654 221110000             0011122222221110000000000


Q NP_000836.2     345 FRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC  424 (908)
Q Consensus       345 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~  424 (908)
                                ......+ +.+.+.+...                      ...+..++..+|||++++++|++++....+
T Consensus       290 ----------~~~~~~~-~~~~~~~~~~----------------------~~~~~~~~~~~ydav~~~~~al~~~~~~~~  336 (433)
T 4F11_A          290 ----------SGKTPQQ-YEREYNNKRS----------------------GVGPSKFHGYAYDGIWVIAKTLQRAMETLH  336 (433)
T ss_dssp             ----------TSCCHHH-HHHHHHHHHT----------------------TSCCCTTHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             ----------CCCCHHH-HHHHHHHhcc----------------------CCChhhcchHHHHHHHHHHHHHHHHHHHHH
Confidence                      0000111 1111111000                      012345678899999999999999875422


Q NP_000836.2     425 PGY---IGLCP-RMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQL---HL  497 (908)
Q Consensus       425 ~~~---~~~~~-~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~---~~  497 (908)
                      ...   ...|. .....++..+.++|++..|.|.+| .+.|+ +|++...+.+++++    ++.++.||.|+...   .+
T Consensus       337 ~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~G~~G-~i~f~-~g~~~~~~~i~~~~----~g~~~~v~~~~~~~~~~~~  410 (433)
T 4F11_A          337 ASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTG-QVVFR-NGERMGTIKFTQFQ----DSREVKVGEYNAVADTLEI  410 (433)
T ss_dssp             HSSSCCCGGGCSSCCHHHHHHHHHHHHTCEEEETTE-EEEEE-TTEEECEEEEEEEE----TTEEEEEEEEETTTTEEEE
T ss_pred             hcCCCCchhhcCCCChHHHHHHHHHHHcCcEEeece-eEEee-CCceeeEEEEEEEE----CCcEEEEEEEECCCCeEEE
Confidence            100   00000 001124556778888889999999 89999 89987788888887    35789999998642   12


Q NP_000836.2     498 KVEDMQWAH  506 (908)
Q Consensus       498 ~~~~i~w~~  506 (908)
                      ....+.|.+
T Consensus       411 ~~~~~~w~g  419 (433)
T 4F11_A          411 INDTIRFQG  419 (433)
T ss_dssp             CTTTCCCSS
T ss_pred             ecCcccCCC
Confidence            223466754


No 43
>4MS4_B Gamma-aminobutyric acid type B receptor; heterodimeric protein complex, Venus Flytrap; HET: NAG, 2C0; 1.9A {Homo sapiens}
Probab=99.72  E-value=2e-22  Score=221.47  Aligned_cols=391  Identities=19%  Similarity=0.262  Sum_probs=246.4  Template_Neff=11.600

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||+++|.++....        ...+.....|++.|++++|+.++ ++|+++++++.|+++++..+.+    
T Consensus         8 ~~~~~~~i~ig~~~~~~~~~~~--------~~~~~~~~~~~~~a~~~~n~~~~-~~~~~i~l~~~d~~~~~~~~~~----   74 (433)
T 4MS4_B            8 PPPSSPPLSIMGLMPLTKEVAK--------GSIGRGVLPAVELAIEQIRNESL-LRPYFLDLRLYDTECDNAKGLK----   74 (433)
T ss_dssp             -CTTCCEEEEEEEECCCTTSTT--------HHHHHHHHHHHHHHHHHHHHTTT-TTTCEEEEEEEECTTCHHHHHH----
T ss_pred             CCCCCCCeEEEEEEecCCcccC--------CcccccHHHHHHHHHHHHHhccC-CCCceEEEEEEcCCCChhHHHH----
Confidence            3456789999999999864310        02456788999999999998764 5578899999998876544333    


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+.+++..                 .++++++||+.++..+..++.++...++|+|++.+..+.+.+...+++++++.++
T Consensus        75 ~~~~l~~~-----------------~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  137 (433)
T 4MS4_B           75 AFYDAIKY-----------------GPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPS  137 (433)
T ss_dssp             HHHHHHHH-----------------SCCCSEEEECCSHHHHHHHHHHGGGGTCEEEESSCCCGGGGCTTTCTTEEESSCC
T ss_pred             HHHHHHHh-----------------CCCeEEEEcCCChhHHHHHHHHccccCCeEEEeccCCHHHcCCCCCCceeeeCCC
Confidence            33333320                 0368899998888777778888889999999988766655443357889999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ...++.++++++++++|+++++++.++.++....+.+++.+++. ++++.....+.     .++...+++++. .++++|
T Consensus       138 ~~~~~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~-----~~~~~~~~~~~~-~~~~~v  210 (433)
T 4MS4_B          138 DNAVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGE-DIEISDTESFS-----NDPCTSVKKLKG-NDVRII  210 (433)
T ss_dssp             GGGHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHTTT-TCEEEEEEEES-----SCTHHHHHHHHH-TTCCEE
T ss_pred             hhhhhHHHHHHHHHcCCCEEEEEEecchhhHHHHHHHHHHHhcC-CeEEEeeeeec-----CChhHHHHHHhc-CCcEEE
Confidence            98889999999988899999999987777777778888877765 46654332221     235556667763 578888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVY-------------QQEEIAEGAVTILPKRASIDGFDRY  344 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~-------------~~~~~~~g~~~~~~~~~~~~~~~~~  344 (908)
                      ++.........+++++++.|+.. ++.|+..+ +........             .......+.+.+.........+..+
T Consensus       211 ~~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~  289 (433)
T 4MS4_B          211 LGQFDQNMAAKVFCCAYEENMYGSKYQWIIPG-WYEPSWWEQVHTEANSSRCLRKNLLAAMEGYIGVDFEPLSSKQIKTI  289 (433)
T ss_dssp             EEECCHHHHHHHHHHHHHTTCCSTTCEEEEES-CSCTTTTC----------CCHHHHHHHHTTCEEEEECSSCCCCCCCT
T ss_pred             EEeCCHHHHHHHHHHHHHcCCcCCCeEEEccC-CcCcchhHHhhccccCCCccHHHHHHHHccceeeEeecCCCCCcccc
Confidence            77766667788899988888753 45666654 221110000             0011122222221110000000000


Q NP_000836.2     345 FRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC  424 (908)
Q Consensus       345 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~  424 (908)
                                ......+ +.+.+.+...                      ...+..++..+|||++++++|++++....+
T Consensus       290 ----------~~~~~~~-~~~~~~~~~~----------------------~~~~~~~~~~~ydav~~~~~al~~~~~~~~  336 (433)
T 4MS4_B          290 ----------SGKTPQQ-YEREYNNKRS----------------------GVGPSKFHGYAYDGIWVIAKTLQRAMETLH  336 (433)
T ss_dssp             ----------TSSCHHH-HHHHHHHHCC----------------------SSCCCTTHHHHHHHHHHHHHHHHHHTCSSC
T ss_pred             ----------CCCCHHH-HHHHHHHhcc----------------------CCChhhcchHHHHHHHHHHHHHHHHHHHHH
Confidence                      0000111 1111111000                      012345678899999999999999875422


Q NP_000836.2     425 PGY---IGLCP-RMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQL---HL  497 (908)
Q Consensus       425 ~~~---~~~~~-~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~---~~  497 (908)
                      ...   ...|. .....++..+.++|++..|.|.+| .+.|+ +|++...+.+++++    ++.++.||.|+...   .+
T Consensus       337 ~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~G~~G-~i~f~-~g~~~~~~~i~~~~----~g~~~~v~~~~~~~~~~~~  410 (433)
T 4MS4_B          337 ASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTG-QVVFR-NGERMGTIKFTQFQ----DSREVKVGEYNAVADTLEI  410 (433)
T ss_dssp             HHHHHHHHHHCCSCCHHHHHHHHHHHHTCEEEETTE-EEEEE-TTEEECEEEEEEEC----SSCEEEEEEEETTTTEEEE
T ss_pred             hcCCCCchhhcCCCChHHHHHHHHHHHcCcEEeece-eEEee-CCceeeEEEEEEEE----CCcEEEEEEEECCCCeEEE
Confidence            100   00000 001124556778888889999999 89999 89987788888887    35789999998642   12


Q NP_000836.2     498 KVEDMQWAH  506 (908)
Q Consensus       498 ~~~~i~w~~  506 (908)
                      ....+.|.+
T Consensus       411 ~~~~~~w~g  419 (433)
T 4MS4_B          411 INDTIRFQG  419 (433)
T ss_dssp             CTTTCCCSS
T ss_pred             ecCcccCCC
Confidence            223466754


No 44
>4MQE_A Gamma-aminobutyric acid type B receptor; heterodimeric protein complex, Venus Flytrap; HET: MAN, NAG, FUC; 2.35A {Homo sapiens}
Probab=99.67  E-value=2e-21  Score=212.36  Aligned_cols=376  Identities=21%  Similarity=0.283  Sum_probs=233.6  Template_Neff=11.700

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.++..           ..+.....|++.|++++|+.+++++|+++++.+.|+++++..+    .+.+.+
T Consensus         3 ~~~i~Ig~i~p~~~~~-----------~~~~~~~~~~~~a~~~~n~~~~~~~g~~i~~~~~d~~~~~~~~----~~~~~~   67 (420)
T 4MQE_A            3 RRAVYIGALFPMSGGW-----------PGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQA----TKYLYE   67 (420)
T ss_dssp             CEEEEEEEEECSSSSC-----------CTHHHHHHHHHHHHHHHHHCTTTCSSEEEEEEEEECTTCHHHH----HHHHHH
T ss_pred             CceeEEEEEEecCCCC-----------CccccHHHHHHHHHHHHHcCCCCCCCcEEEEEEecCCCChHHH----HHHHHH
Confidence            4689999999997642           2456788999999999999877666889999999887664432    333333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                  .++++++||+.++.....++..+...++|+|++.+..+.+++...+++++++.++....
T Consensus        68 l~~------------------~~~v~~iig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~  129 (420)
T 4MQE_A           68 LLY------------------NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLH  129 (420)
T ss_dssp             HHS------------------SSSCCSEEECCSHHHHHHHHHHGGGGTCEEEESSCCCGGGCCTTTCTTEEESSCCGGGH
T ss_pred             HHh------------------CCCeEEEEEcCchHHHHHHHHHHhhcCCEEEechhcChhhcCCCCCCceEecCCChhhc
Confidence            332                  14788999988777777777888899999999877665554333468899999998888


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      +.++++++++++|++|++++.++.++....+.+++.+++. ++++.....+.     .+....+++++. .++|+|++..
T Consensus       130 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~-----~d~~~~~~~~~~-~~~~~ii~~~  202 (420)
T 4MQE_A          130 NPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEA-GIEITFRQSFF-----SDPAVPVKNLKR-QDARIIVGLF  202 (420)
T ss_dssp             HHHHHHHHHHHTCCEEEEEEESCHHHHHHHHHHHHHHHHT-TCEEEEEEEES-----SCCHHHHHHHHH-TTCCEEEEEC
T ss_pred             hHHHHHHHHHhCCcEEEEEEeCCcchhhHHHHHHHHHHHC-CcEEEEEeccc-----CCCchHHHHHHh-CCCEEEEEEC
Confidence            8889998888899999999977777777778888887765 45554332221     234455666663 5788887776


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSG-HFLWIGSDS----WGSKIAPV-----YQQEEIAEGAVTILPKRASIDGFDRYFRSRTL--  350 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~-~~~~i~~~~----~~~~~~~~-----~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~--  350 (908)
                      .......+++++++.|+.. .+.|+..+.    |.......     ........|.+......         +.....  
T Consensus       203 ~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~---------~~~~~~~~  273 (420)
T 4MQE_A          203 YETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVM---------LNPANTRS  273 (420)
T ss_dssp             CHHHHHHHHHHHHHTTCCSTTCEEEEESCSCTTGGGSCCTTCCSCHHHHHHHHTTCEEEEECC---------SCSSCCCC
T ss_pred             CHHHHHHHHHHHHHcCccCCCeEEEeecccccchhhhcCCCCCCCHHHHHHHHhcceeEEEec---------cCCCCCCc
Confidence            6656778888888887643 345665431    11000000     00001122222111000         000000  


Q NP_000836.2     351 ANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGY-IG  429 (908)
Q Consensus       351 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~-~~  429 (908)
                      ...+....|.+.+.+.++..                      +.......++..+|||++++++|++++........ ..
T Consensus       274 ~~~~~~~~f~~~~~~~~~~~----------------------p~~~~~~~~~~~~ydav~~~~~al~~~~~~~~~~~~~~  331 (420)
T 4MQE_A          274 ISNMTSQEFVEKLTKRLKRH----------------------PEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRL  331 (420)
T ss_dssp             TTSCCHHHHHHHHHHHCSSC----------------------TTTSTTTTTHHHHHHHHHHHHHHHHHHC--------CG
T ss_pred             ccCCCHHHHHHHHHHHHhcC----------------------CccCCCCcchHHHHHHHHHHHHHHHHHhccCccCCCCH
Confidence            00011111222222211100                      00001124567899999999999998864321100 00


Q NP_000836.2     430 LCPR-MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       430 ~~~~-~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .|.. .....+..+.+.+++..|.|.+| .+.||++|++...+.+.+++    ++.++.+|.|+..
T Consensus       332 ~~~~~~~~~~~~~l~~~l~~~~~~G~~G-~~~f~~~g~~~~~~~v~~~~----~~~~~~v~~~~~~  392 (420)
T 4MQE_A          332 EDFNYNNQTITDQIYRAMNSSSFEGVSG-HVVFDASGSRMAWTLIEQLQ----GGSYKKIGYYDST  392 (420)
T ss_dssp             GGCCTTCHHHHHHHHHHHHTCCEEETTE-EECBCTTSBBCCEEEEEEEC----SSSEEEEEEEETT
T ss_pred             HHcCCCChHHHHHHHHHHhcCceecccc-eEEEcCCCCcceeEEEEEee----CCceEEEEEEEcC
Confidence            0000 00123445667777788999988 89999999987777788876    3578899999865


No 45
>4MS4_A Gamma-aminobutyric acid type B receptor; heterodimeric protein complex, Venus Flytrap; HET: 2C0, NAG; 1.9A {Homo sapiens}
Probab=99.67  E-value=2e-21  Score=212.36  Aligned_cols=376  Identities=21%  Similarity=0.283  Sum_probs=233.6  Template_Neff=11.700

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.++..           ..+.....|++.|++++|+.+++++|+++++.+.|+++++..+    .+.+.+
T Consensus         3 ~~~i~Ig~i~p~~~~~-----------~~~~~~~~~~~~a~~~~n~~~~~~~g~~i~~~~~d~~~~~~~~----~~~~~~   67 (420)
T 4MS4_A            3 RRAVYIGALFPMSGGW-----------PGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQA----TKYLYE   67 (420)
T ss_dssp             CEEEEEEEEECSSSSC-----------CTHHHHHHHHHHHHHHHHTCTTTCTTEEEEEEEEECTTCHHHH----HHHHHH
T ss_pred             CceeEEEEEEecCCCC-----------CccccHHHHHHHHHHHHHcCCCCCCCcEEEEEEecCCCChHHH----HHHHHH
Confidence            4689999999997642           2456788999999999999877666889999999887664432    333333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                  .++++++||+.++.....++..+...++|+|++.+..+.+++...+++++++.++....
T Consensus        68 l~~------------------~~~v~~iig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~  129 (420)
T 4MS4_A           68 LLY------------------NDPIKIILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLH  129 (420)
T ss_dssp             HHS------------------SSSCCSEEECCSHHHHHHHHHHGGGGTCEEEESSCCCGGGGCTTTSTTEEESSCCGGGH
T ss_pred             HHh------------------CCCeEEEEEcCchHHHHHHHHHHhhcCCEEEechhcChhhcCCCCCCceEecCCChhhc
Confidence            332                  14788999988777777777888899999999877665554333468899999998888


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      +.++++++++++|++|++++.++.++....+.+++.+++. ++++.....+.     .+....+++++. .++|+|++..
T Consensus       130 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~-----~d~~~~~~~~~~-~~~~~ii~~~  202 (420)
T 4MS4_A          130 NPTRVKLFEKWGWKKIATIQQTTEVFTSTLDDLEERVKEA-GIEITFRQSFF-----SDPAVPVKNLKR-QDARIIVGLF  202 (420)
T ss_dssp             HHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEES-----SCCHHHHHHHHH-TTCCEEEEEC
T ss_pred             hHHHHHHHHHhCCcEEEEEEeCCcchhhHHHHHHHHHHHC-CcEEEEEeccc-----CCCchHHHHHHh-CCCEEEEEEC
Confidence            8889998888899999999977777777778888887765 45554332221     234455666663 5788887776


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSG-HFLWIGSDS----WGSKIAPV-----YQQEEIAEGAVTILPKRASIDGFDRYFRSRTL--  350 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~-~~~~i~~~~----~~~~~~~~-----~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~--  350 (908)
                      .......+++++++.|+.. .+.|+..+.    |.......     ........|.+......         +.....  
T Consensus       203 ~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~---------~~~~~~~~  273 (420)
T 4MS4_A          203 YETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVEGHITTEIVM---------LNPANTRS  273 (420)
T ss_dssp             CHHHHHHHHHHHHHHTCCSTTCEEEEETTSCTTGGGSCCTTCCCCHHHHHHHHTTCEEEEECC---------SCSSCCCC
T ss_pred             CHHHHHHHHHHHHHcCccCCCeEEEeecccccchhhhcCCCCCCCHHHHHHHHhcceeEEEec---------cCCCCCCc
Confidence            6656778888888887643 345665431    11000000     00001122222111000         000000  


Q NP_000836.2     351 ANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGY-IG  429 (908)
Q Consensus       351 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~-~~  429 (908)
                      ...+....|.+.+.+.++..                      +.......++..+|||++++++|++++........ ..
T Consensus       274 ~~~~~~~~f~~~~~~~~~~~----------------------p~~~~~~~~~~~~ydav~~~~~al~~~~~~~~~~~~~~  331 (420)
T 4MS4_A          274 ISNMTSQEFVEKLTKRLKRH----------------------PEETGGFQEAPLAYDAIWALALALNKTSGGGGRSGVRL  331 (420)
T ss_dssp             TTSCCHHHHHHHHHHHCSSC----------------------GGGSTTTTTHHHHHHHHHHHHHHHHHHC--------CG
T ss_pred             ccCCCHHHHHHHHHHHHhcC----------------------CccCCCCcchHHHHHHHHHHHHHHHHHhccCccCCCCH
Confidence            00011111222222211100                      00001124567899999999999998864321100 00


Q NP_000836.2     430 LCPR-MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       430 ~~~~-~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .|.. .....+..+.+.+++..|.|.+| .+.||++|++...+.+.+++    ++.++.+|.|+..
T Consensus       332 ~~~~~~~~~~~~~l~~~l~~~~~~G~~G-~~~f~~~g~~~~~~~v~~~~----~~~~~~v~~~~~~  392 (420)
T 4MS4_A          332 EDFNYNNQTITDQIYRAMNSSSFEGVSG-HVVFDASGSRMAWTLIEQLQ----GGSYKKIGYYDST  392 (420)
T ss_dssp             GGCCTTCSHHHHHHHHHHHTCEEEETTE-EEECCTTTCSCCEEEEEEEE----TTEEEEEEEEETT
T ss_pred             HHcCCCChHHHHHHHHHHhcCceecccc-eEEEcCCCCcceeEEEEEee----CCceEEEEEEEcC
Confidence            0000 00123445667777788999988 89999999987777788876    3578899999865


No 46
>3Q41_C Glutamate [NMDA] receptor subunit zeta-1; NTD, NMDA, GluN1, ion channel; HET: NAG; 3.4A {Rattus norvegicus}
Probab=99.66  E-value=4.8e-21  Score=206.51  Aligned_cols=348  Identities=19%  Similarity=0.271  Sum_probs=226.6  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI--LDTCSRDTYALEQSLTF  119 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~--~d~~~~~~~a~~~~~~~  119 (908)
                      ..++++||+++|.+                  ....|++.|++++|++++   +.++++..  .|++.++..   .+.+.
T Consensus         3 ~~~~i~Ig~i~~~~------------------~~~~~~~~a~~~~n~~~~---~~~i~l~~~~~d~~~~~~~---~~~~~   58 (384)
T 3Q41_C            3 DPKIVNIGAVLSTR------------------KHEQMFREAVNQANKRHG---SWKIQLNATSVTHKPNAIQ---MALSV   58 (384)
T ss_dssp             -CCCBEEEEEESSH------------------HHHHHHHHHHHTTTTTSC---TTTSCBCCEEEECCSSSSH---HHHHC
T ss_pred             CCceeEEEeeechH------------------HHHHHHHHHHHHHHhcCC---CcceEEEEEEecCCCCHHH---HHHHH
Confidence            35789999999874                  245789999999998754   34566655  776654322   12222


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAAS-----SVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSR  194 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s-----~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~  194 (908)
                      .+.+..                   +++++++|+..+     .....++.++...++|+|++.+..+.+.+...++++++
T Consensus        59 ~~~l~~-------------------~~v~~vig~~~~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~  119 (384)
T 3Q41_C           59 CEDLIS-------------------SQVYAILVSHPPTPNDHFTPTPVSYTAGFYRIPVLGLTTRMSIYSDKSIHLSFLR  119 (384)
T ss_dssp             CCCCGG-------------------GCEEEEEECCCCSTTTTTTHHHHHHHHHTTTCCEEESSCCCGGGTCTTSCTTEEE
T ss_pred             HHHHHh-------------------cCceEEEEcCCCCCCCCCChhHHHHHhHhcCCCEEecccCChhHcCCcccccEee
Confidence            222221                   478899997665     24456677888899999998876665554434688999


Q NP_000836.2     195 VVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       195 ~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      +.++....+.++++++++++|+++++++.++.++....+.+++.+++. ++++.....+.  ....+....+++++. .+
T Consensus       120 ~~~~~~~~~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~l~~-~~  195 (384)
T 3Q41_C          120 TVPPYSHQSSVWFEMMRVYNWNHIILLVSDDHEGRAAQKRLETLLEER-ESKAEKVLQFD--PGTKNVTALLMEARE-LE  195 (384)
T ss_dssp             SSCCSGGGHHHHHHHHHTTTCCCCEEEEESSHHHHHHHHHHHHHHHTS-SCCCSEEEEEC--SSCSCCHHHHHHHHT-SS
T ss_pred             cCCCHHHHHHHHHHHHHHcCCcEEEEEEecCcChhHHHHHHHHHHHhc-CceeEEEEeeC--CCChhHHHHHHHHHh-CC
Confidence            999998889999999988899999999987777777777888777765 35554332222  122345566777763 57


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANN  353 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~  353 (908)
                      +++|++.........+++++++.|+.. ++.|+..+.|.....    ......+.+.                       
T Consensus       196 ~~~ii~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~----~~~~~~~~~~-----------------------  248 (384)
T 3Q41_C          196 ARVIILSASEDDAATVYRAAAMLNMTGSGYVWLVGEREISGNA----LRYAPDGIIG-----------------------  248 (384)
T ss_dssp             CCEEEEECCHHHHHHHHHHHHTTTCSSTTCEEEECSSTTSTHH----HHHCCTTCEE-----------------------
T ss_pred             CeEEEEECCHHHHHHHHHHHHHcCCcCCCeEEEEecccCCcch----HhhCCCcEEE-----------------------
Confidence            888888777777788888888888753 456766543321100    0000000000                       


Q NP_000836.2     354 RRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG-YIGLCP  432 (908)
Q Consensus       354 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~-~~~~~~  432 (908)
                           +    . .                             ..+..++..+|||++++++|++++....+.. ....|.
T Consensus       249 -----~----~-~-----------------------------~~~~~~~~~~yDa~~~~~~al~~~~~~~~~~~~~~~c~  289 (384)
T 3Q41_C          249 -----L----Q-L-----------------------------INGKNESAHISDAVGVVAQAVHELLEKENITDPPRGCV  289 (384)
T ss_dssp             -----E----E-E-----------------------------TTTTCHHHHHHHHHHHHHHHHHHHTTSSSCCCCCSCCT
T ss_pred             -----E----E-e-----------------------------cCCCcchhHHHHHHHHHHHHHHHHHHccCCCCCCCCcc
Confidence                 0    0 0                             0112456789999999999999887543211 011222


Q NP_000836.2     433 RM--STIDGKELLGYIRA-VNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLH-LKVEDMQWAHR  507 (908)
Q Consensus       433 ~~--~~~~~~~l~~~l~~-~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~-~~~~~i~w~~~  507 (908)
                      ..  ....+..+.+.|++ ..|.|.+| .+.||++|++. ..+.+++++    ++.++.||.|+.... +....+.|.++
T Consensus       290 ~~~~~~~~~~~l~~~l~~~~~~~g~~G-~i~fd~~g~~~~~~~~i~~~~----~~~~~~vg~~~~~~~~~~~~~~~w~~~  364 (384)
T 3Q41_C          290 GNTNIWKTGPLFKRVLMSSKYADGVTG-RVEFNEDGDRKFANYSIMNLQ----NRKLVQVGIYNGTHVIPNDRKIIWPGG  364 (384)
T ss_dssp             TCCCCCTHHHHHHHHHHSCEECSCSSS-CEECCSSSCCCCCCEEEEEEE----TTEEEEEEEEETTEEEECSSCCCBTTT
T ss_pred             CCCchhccHHHHHHHHhcCCcccCCCc-cEEECCCCCccceEEEEEEee----CCcEEEEEEEeCCCcccCCCCccCCCC
Confidence            11  11234456677765 46899988 89999999985 788888887    357899999986531 22235778653


No 47
>5KC8_A Glutamate receptor ionotropic, delta-2; ionotropic glutamate receptor (iGluR), neurotransmission; HET: EDO; 1.751A {Homo sapiens}
Probab=99.64  E-value=9.9e-21  Score=207.43  Aligned_cols=378  Identities=16%  Similarity=0.219  Sum_probs=229.7  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILD-TCSRDTYALEQSLTFV  120 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d-~~~~~~~a~~~~~~~~  120 (908)
                      .+++++||+++|.++.                ....|+++|++++|+++++++|.++++.+.| +++++..+.+.    +
T Consensus         3 ~~~~i~Ig~i~p~sg~----------------~~~~a~~~A~~~in~~~~~~~~~~i~~~~~d~~~~~~~~~~~~----~   62 (429)
T 5KC8_A            3 GDSIIHIGAIFDESAK----------------KDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQE----A   62 (429)
T ss_dssp             -CCCEEEEEEEETTCH----------------HHHHHHHHHHHHHHHCTTSSTTCCEEEEEEEECTTCHHHHHHH----H
T ss_pred             CCceeeeEEEeeCCCh----------------hHHHHHHHHHHHHHhCCCccCCCeEEEEEEecCCCCHHHHHHH----H
Confidence            4578999999998752                4668999999999998777778899999888 66654433332    3


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELS--------DNTRYDFF  192 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~--------~~~~~~~~  192 (908)
                      .+++.                   ++++++||+.++..+..++.++...+||+|++.+.++.+.        ....++++
T Consensus        63 ~~l~~-------------------~~v~avig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~  123 (429)
T 5KC8_A           63 CELMN-------------------QGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYT  123 (429)
T ss_dssp             HHHHH-------------------HCCSCEEEEECHHHHHHHHHHHHHHTCCEEEEECCSTTCCCCCCCCCCCCSSCCCE
T ss_pred             HHHHh-------------------cCceEEEcCCChHHHHHHHHHHHhcCCCEEEeecCCCCCCCCcCCccccCCCCcce
Confidence            33322                   4788999998887777788888999999999877654211        11246889


Q NP_000836.2     193 SRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIP------REPRPGEFEKII  266 (908)
Q Consensus       193 ~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~------~~~~~~~~~~~~  266 (908)
                      +++.|+. .+++++++++++++|++|++++.+ +++....+.+.+.+++. ++++......+      ......++...+
T Consensus       124 ~~~~p~~-~~~~a~~~~l~~~~~~~v~ii~~~-~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~~~l  200 (429)
T 5KC8_A          124 LSVRPPV-YLHDVILRVVTEYAWQKFIIFYDS-EYDIRGIQEFLDKVSQQ-GMDVALQKVENNINKMITTLFDTMRIEEL  200 (429)
T ss_dssp             EECSCCC-CHHHHHHHHHHHTTCCEEEEEECT-TCCGGGGHHHHHHHHHT-TCEEEEEECCSCHHHHHHHHHHHCCHHHH
T ss_pred             eecCCCh-hHHHHHHHHHHHcCCCEEEEEeCC-hHHHHHHHHHHHHHHhc-CceEEEEeecccccccchhhhhhhHHHHH
Confidence            9999987 788899999988999999999975 67777777788777665 35554321110      001123455666


Q NP_000836.2     267 KRLLETPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       267 ~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      ++++. .+ +.|++......+..+++++++.|+.. .+.|+..+.+...............+...+....          
T Consensus       201 ~~~~~-~~-~~vv~~~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------  268 (429)
T 5KC8_A          201 NRYRD-TL-RRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTF----------  268 (429)
T ss_dssp             HHHHH-HT-TEEEEESCHHHHHHHHHHHHHTTSSCTTCEEEEECSCCCHHHHHHHHHHCCSEEEEEEEEC----------
T ss_pred             HHHhh-cC-CEEEEEcCHHHHHHHHHHHHHcCCCcCCeEEEEecCCccccchHHHHHHHhcceEEEEeec----------
Confidence            66653 34 44445555667788999999888764 4567766533221110000000111111111000          


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      ..   .......+|.+.+++.+..              |......    ...+..++..+|||++++++|++++....+.
T Consensus       269 ~~---~~~~~~~~f~~~~~~~~~~--------------~~~~~~~----~~~~~~~~~~~yDav~~~~~al~~~~~~~~~  327 (429)
T 5KC8_A          269 PV---PQNISQRCFRGNHRISSTL--------------CDPKDPF----AQNMEISNLYIYDTVLLLANAFHKKLEDRKW  327 (429)
T ss_dssp             CC---CCSHHHHSEETTEECCHHH--------------HCTTSHH----HHTCCHHHHHHHHHHHHHHHHHHHHHHTTCC
T ss_pred             CC---ChhhchhhHhhcccccccC--------------CCCCCcc----ccccChHHHHHHHHHHHHHHHHHHHHHcccc
Confidence            00   0000111122222222110              0000000    0123456788999999999999988754321


Q NP_000836.2     426 G--YIGLCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITN-KSTEYKVIGHWTNQL  495 (908)
Q Consensus       426 ~--~~~~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~-~~~~~~~Vg~~~~~~  495 (908)
                      .  ....|...   ...++..+.+.|++..|.|.+| ++.|+++|++. ..+.|++++... .++.++.||.|+...
T Consensus       328 ~~~~~~~c~~~~~~~~~~~~~l~~~l~~~~f~G~~G-~i~f~~~g~~~~~~~~i~~~~~~~~~~~~~~~vg~w~~~~  403 (429)
T 5KC8_A          328 HSMASLSCIRKNSKPWQGGRSMLETIKKGGVSGLTG-ELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVT  403 (429)
T ss_dssp             CCCCCCCSSSTTCCCCTTHHHHHHHHHTCEEEETTE-EEECCTTSBCCCCEEEEEEC--------CCEEEEEEETTT
T ss_pred             cCCCCCccccccCCccccHHHHHHHHHhCceeecce-eEEeCCCCCcCcceEEEEeeecccccCCCeEEEEEEeCCC
Confidence            0  01122211   0114556778888889999999 89999999886 577888887310 124689999998753


No 48
>3OM0_A Glutamate receptor, ionotropic kainate 5; Membrane Protein, Ion channel; HET: BMA, GOL, NAG; 1.401A {Rattus norvegicus}
Probab=99.62  E-value=2.1e-20  Score=201.91  Aligned_cols=370  Identities=15%  Similarity=0.164  Sum_probs=229.1  Template_Neff=12.200

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||+++|.++.             .+.....|+++|++++|+++++++|+++++++.|++++...   .+.+.+++
T Consensus         2 ~~~i~ig~~~~~~~~-------------~g~~~~~~~~~a~~~~n~~~~~~~~~~l~~~~~d~~~~~~~---~~~~~~~~   65 (393)
T 3OM0_A            2 LSSLRMAAILDDQTV-------------CGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQY---ETTDTMCQ   65 (393)
T ss_dssp             CCEEEEEEEECCCCS-------------SCCCHHHHHHHHHHHHHHSCCSSCCCEEEEEEEECCSSCHH---HHHHHHHH
T ss_pred             CccceeeeeecCCCC-------------CcHHHHHHHHHHHHHHHccCCCCCCCEEEEEEEEcCCCChH---HHHHHHHH
Confidence            468999999998763             45678899999999999988777788999999887654321   12222333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASS-VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~-~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +..                   ++++++||+.++. ....++.++...++|+|++.+.++.+... .+++++++.|++..
T Consensus        66 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~~~  125 (393)
T 3OM0_A           66 ILP-------------------KGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQY-LRFASVSLYPSNED  125 (393)
T ss_dssp             HGG-------------------GCCSCEECCSSCHHHHHHHHHHHHHHTCCEEECSCCCCC-----CCSCCEESSCCHHH
T ss_pred             hcc-------------------cCceEEECCCCCHHhHHHHHHHHhhcCCCEEEecCCCCccccc-ceeeEEEcCCCHHH
Confidence            322                   5789999998875 56777888899999999988765544322 35678899999888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .+.++++++++++|+++++++.+++++....+ +.+.+++. +..+ ....+.   ...++...+++++. .++++|++.
T Consensus       126 ~~~~l~~~l~~~~~~~v~ii~~~~~~~~~~~~-~~~~~~~~-~~~~-~~~~~~---~~~~~~~~~~~l~~-~~~~~i~~~  198 (393)
T 3OM0_A          126 VSLAVSRILKSFNYPSASLICAKAECLLRLEE-LVRGFLIS-KETL-SVRMLD---DSRDPTPLLKEIRD-DKVSTIIID  198 (393)
T ss_dssp             HHHHHHHHHHHTTSCCEEEEESSTTHHHHTHH-HHHHHHHS-SSCE-EEEECC----CCCSHHHHHHHHH-HTCSEEEEE
T ss_pred             HHHHHHHHHHHcCCCeEEEEEechhHHHHHHH-HHHhhccC-CCee-EEEecC---CCCCcHHHHHHHhc-CCCcEEEEE
Confidence            89999999988899999999977766654444 44444432 2111 111111   22345566777763 578999888


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ........+++++++.|+.. .+.|+..+........ ........+...+...           .    ...+....|.
T Consensus       199 ~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~----~~~~~~~~f~  262 (393)
T 3OM0_A          199 ANASISHLVLRKASELGMTSAFYKYILTTMDFPILHL-DGIVEDSSNILGFSMF-----------N----TSHPFYPEFV  262 (393)
T ss_dssp             SCHHHHHHHHHHHHHTTTTSTTCEEEECCTTGGGCCC-TTTCCSSCSEEEEECC-----------C----TTSTTHHHHH
T ss_pred             CCHHHHHHHHHHHHHcCCCCCCceEEEcCCCcccCCH-HHhcccCceEEEEEEe-----------c----CCCccHHHHH
Confidence            77777888999998888753 3456654321111000 0001111111111100           0    0011111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG-YIGLCPRMS-TID  438 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~-~~~~~~~~~-~~~  438 (908)
                      +.+.+.+..             .|...      ....+..++..+|||+++++++++++....+.. ....|.... ..+
T Consensus       263 ~~~~~~~~~-------------~~~~~------~~~~~~~~~~~~yda~~~~~~a~~~~~~~~~~~~~~~~c~~~~~~~~  323 (393)
T 3OM0_A          263 RSLNMSWRE-------------NCEAS------TYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPH  323 (393)
T ss_dssp             HHHHHHHTT-------------TSCGG------GCCSCCHHHHHHHHHHHHHHHHHHHHTTTSCCCCCCCCTTCCCCCTT
T ss_pred             HHHHHhchh-------------ccccC------CCCCCChhHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCCcccchh
Confidence            222222211             01000      001234567789999999999999986532110 112232111 124


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                      +..+.+.|++..|.|.+| ++.||++|++.. .+.+++++    .+.+..||.|....
T Consensus       324 ~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~  376 (393)
T 3OM0_A          324 GTSLMNYLRMVEYDGLTG-RVEFNSKGQRTNYTLRILEKS----RQGHREIGVWYSNR  376 (393)
T ss_dssp             HHHHHHHHTTCCEEETTE-EECBCTTSCBCSCEEEEEEEE----TTEEEEEEEEECC-
T ss_pred             HHHHHHHHhcCccccccc-eeeeCCCCCcCceEEEEEEec----ccceEEEEEEecCC
Confidence            556778888889999988 899999998875 77787776    25688999998764


No 49
>3QLU_B Glutamate receptor, ionotropic kainate 5; Membrane protein, Glycosylation; HET: NAG, GOL; 2.906A {Rattus norvegicus}
Probab=99.62  E-value=2.1e-20  Score=201.91  Aligned_cols=370  Identities=15%  Similarity=0.164  Sum_probs=231.0  Template_Neff=12.200

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||+++|.++.             .+.....|+++|++++|+++++++|+++++++.|++++...   .+.+.+++
T Consensus         2 ~~~i~ig~~~~~~~~-------------~g~~~~~~~~~a~~~~n~~~~~~~~~~l~~~~~d~~~~~~~---~~~~~~~~   65 (393)
T 3QLU_B            2 LSSLRMAAILDDQTV-------------CGRGERLALALAREQINGIIEVPAKARVEVDIFELQRDSQY---ETTDTMCQ   65 (393)
T ss_dssp             CCCEEEEEEECCCSS-------------SCCSHHHHHHHHHHHHHHSCCSSCCCCEEEEEEECSSSCHH---HHHHHHHH
T ss_pred             CccceeeeeecCCCC-------------CcHHHHHHHHHHHHHHHccCCCCCCCEEEEEEEEcCCCChH---HHHHHHHH
Confidence            468999999998763             45678899999999999988777788999999887654321   12222333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASS-VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~-~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +..                   ++++++||+.++. ....++.++...++|+|++.+.++.+... .+++++++.|++..
T Consensus        66 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~~~  125 (393)
T 3QLU_B           66 ILP-------------------KGVVSVLGPSSSPASASTVSHICGEKEIPHIKVGPEETPRLQY-LRFASVSLYPSNED  125 (393)
T ss_dssp             HGG-------------------GCCSCEECCSSCHHHHHHHHHHHHHHTCCEEECSCCSCCCCTT-SCCCEEESSCCHHH
T ss_pred             hcc-------------------cCceEEECCCCCHHhHHHHHHHHhhcCCCEEEecCCCCccccc-ceeeEEEcCCCHHH
Confidence            322                   5789999998875 56777888899999999988765544322 35678899999888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .+.++++++++++|+++++++.+++++....+ +.+.+++. +..+ ....+.   ...++...+++++. .++++|++.
T Consensus       126 ~~~~l~~~l~~~~~~~v~ii~~~~~~~~~~~~-~~~~~~~~-~~~~-~~~~~~---~~~~~~~~~~~l~~-~~~~~i~~~  198 (393)
T 3QLU_B          126 VSLAVSRILKSFNYPSASLICAKAECLLRLEE-LVRGFLIS-KETL-SVRMLD---DSRDPTPLLKEIRD-DKVSTIIID  198 (393)
T ss_dssp             HHHHHHHHHHHTTSCCEEEEESSTTHHHHTHH-HHTTSCBB-TTTE-EEEECC---SSCCCHHHHHHHHH-TTCCEEEEE
T ss_pred             HHHHHHHHHHHcCCCeEEEEEechhHHHHHHH-HHHhhccC-CCee-EEEecC---CCCCcHHHHHHHhc-CCCcEEEEE
Confidence            89999999988899999999977766654444 44444432 2111 111111   22345566777763 578999888


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ........+++++++.|+.. .+.|+..+........ ........+...+...           .    ...+....|.
T Consensus       199 ~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~----~~~~~~~~f~  262 (393)
T 3QLU_B          199 ANASISHLVLRKASELGMTSAFYKYILTTMDFPILHL-DGIVEDSSNILGFSMF-----------N----TSHPFYPEFV  262 (393)
T ss_dssp             SCHHHHHHHHHHHHHTTTTSSSCEEEECCSCCTTCCC-TTTCCSSCEEEEEECC-----------C----TTSTTHHHHH
T ss_pred             CCHHHHHHHHHHHHHcCCCCCCceEEEcCCCcccCCH-HHhcccCceEEEEEEe-----------c----CCCccHHHHH
Confidence            77777888999998888753 3456654321111000 0001111111111100           0    0011111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG-YIGLCPRMS-TID  438 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~-~~~~~~~~~-~~~  438 (908)
                      +.+.+.+..             .|...      ....+..++..+|||+++++++++++....+.. ....|.... ..+
T Consensus       263 ~~~~~~~~~-------------~~~~~------~~~~~~~~~~~~yda~~~~~~a~~~~~~~~~~~~~~~~c~~~~~~~~  323 (393)
T 3QLU_B          263 RSLNMSWRE-------------NCEAS------TYPGPALSAALMFDAVHVVVSAVRELNRSQEIGVKPLACTSANIWPH  323 (393)
T ss_dssp             HHHHHHHHH-------------HCSSS------CCCCCCHHHHHHHHHHHHHHHHHHHHHTTSCCCCCCCCTTSCCCCTT
T ss_pred             HHHHHhchh-------------ccccC------CCCCCChhHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCCcccchh
Confidence            222222211             01000      001234567789999999999999986532110 112232111 124


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                      +..+.+.|++..|.|.+| ++.||++|++.. .+.+++++    .+.+..||.|....
T Consensus       324 ~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~  376 (393)
T 3QLU_B          324 GTSLMNYLRMVEYDGLTG-RVEFNSKGQRTNYTLRILEKS----RQGHREIGVWYSNR  376 (393)
T ss_dssp             HHHHHHHHHTCCEEETTE-EECBCTTSCBCSCEEEEEECC----SSSCCEEEEEESSS
T ss_pred             HHHHHHHHhcCccccccc-eeeeCCCCCcCceEEEEEEec----ccceEEEEEEecCC
Confidence            556778888889999988 899999998875 77787776    25688999998764


No 50
>5FWY_B GLUTAMATE RECEPTOR 2, GLUTAMATE RECEPTOR; TRANSPORT PROTEIN; HET: SO4, NAG; 2.12A {RATTUS NORVEGICUS}
Probab=99.62  E-value=2.4e-20  Score=201.38  Aligned_cols=372  Identities=13%  Similarity=0.153  Sum_probs=227.7  Template_Neff=11.900

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDL-LSNITLGVRILD-TCSRDTYALEQSLTFV  120 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~i-l~g~~l~~~~~d-~~~~~~~a~~~~~~~~  120 (908)
                      +++++||+++|.++.                ....|++.|++++|+++++ ++|+++++++.| +.+++..    ..+.+
T Consensus         3 ~~~i~Ig~~~~~~~~----------------~~~~~~~~a~~~~n~~g~~~~~g~~l~~~~~d~~~~~~~~----~~~~~   62 (390)
T 5FWY_B            3 PNTISIGGLFMRNTV----------------QEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFS----VTNAF   62 (390)
T ss_dssp             CSEEEEEEEECTTCH----------------HHHHHHHHHHHHHHTCCCTTTCSSEEEEEEEECSSCCHHH----HHHHH
T ss_pred             CceeEEEEeecCCCH----------------HHHHHHHHHHHHHHcCCCCCCCCceEEEEEEecCCCChHH----HHHHH
Confidence            568999999998752                4668999999999998765 357888888876 4444332    22233


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      .+++.                   +++++++|+.++..+..++..+...++|+|++.....     ..+++++++.|+  
T Consensus        63 ~~l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~p~--  116 (390)
T 5FWY_B           63 CSQFS-------------------RGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTD-----ADVQFVIQMRPA--  116 (390)
T ss_dssp             HHHHH-------------------HCCSCEEECCCTTTHHHHHHHHHHHTCCEEECSCCCS-----SCCSSEEECSCC--
T ss_pred             HHHhh-------------------CCeeEEEcCCCchhHHHHHHHHHhcCCceeeCCCCCC-----CCCCcEEEeecc--
Confidence            33322                   5788999998887777788888999999998775432     246788998887  


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                       +++++++++++++|+++++++++ .++....+.+++.+++. ++++......+. .+..++...+++++. .++++|++
T Consensus       117 -~~~~~~~~~~~~~~~~v~vl~~~-~~~~~~~~~~~~~~~~~-~~~v~~~~~~~~-~~~~~~~~~~~~l~~-~~~~~vv~  191 (390)
T 5FWY_B          117 -LKGAILSLLSYYKWEKFVYLYDT-ERGFSVLQAIMEAAVQN-NWQVTARSVGNI-KDVQEFRRIIEEMDR-RQEKRYLI  191 (390)
T ss_dssp             -CHHHHHHHHHHTTCCEEEEEECS-TTCSHHHHHHHHHHHHH-TCEEEEEECTTC-CSHHHHHHHHHHHHH-TTCCEEEE
T ss_pred             -HHHHHHHHHHHcCCcEEEEEEeC-cccHHHHHHHHHHHHhC-CCeEEEEEeCCC-CCHHHHHHHHHHHhh-cCCcEEEE
Confidence             46788888888899999999954 67777777777777664 345433211110 122456667777763 57898888


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      ......+..+++++++.|+.. .+.|+..+.+...... ........+...+....               ...+....|
T Consensus       192 ~~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~~---------------~~~~~~~~f  255 (390)
T 5FWY_B          192 DCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILL-ERVMHGGANITGFQIVN---------------NENPMVQQF  255 (390)
T ss_dssp             ESCHHHHHHHHHHHHHTTCCSTTCEEEECCTTGGGSCC-HHHHHHTCEEEEEESCC---------------TTSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHhCCccCCeeEEEecCCcchhcH-HHHhcCCccEEEEEEec---------------CCCHHHHHH
Confidence            776677788899998888753 3556665433221100 00001111111111000               001111223


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~~~~-  434 (908)
                      .+.+++.+......         .+          ...+..++..+||+++++++|++++......    .....|... 
T Consensus       256 ~~~~~~~~~~~~~~---------~~----------~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~c~~~~  316 (390)
T 5FWY_B          256 IQRWVRLDEREFPE---------AK----------NAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANP  316 (390)
T ss_dssp             HHHHTTSCTTTSTT---------CT----------TSCCCHHHHHHHHHHHHHHHHHHHHHHTTCCCCSSSCCSCTTCSS
T ss_pred             HHHHHhcCcccCCC---------CC----------CCCCChHHHHHHHHHHHHHHHHHHHHHcCCCcccCCCCCcccCCC
Confidence            23232222110000         00          0123456778999999999999988653210    001122110 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                        ...++..+.+.|++..|.|.+| ++.||++|++. ..+.+++++.    +.++.+|.|.....++.....|+
T Consensus       317 ~~~~~~~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~~i~~~~~----~~~~~vg~w~~~~~~~~~~~~~~  385 (390)
T 5FWY_B          317 AVPWSQGIDIERALKMVQVQGMTG-NIQFDTYGRRTNYTIDVYEMKV----SGSRKAGYWNEYERFVPFSGTKH  385 (390)
T ss_dssp             CCCCTTHHHHHHHHHTCCEEETTE-EEEECTTSCEESCCEEEEEEC------CEEEEEEEETTTEEEECCC---
T ss_pred             CCcchhHHHHHHHHhcCCccCCCc-eEEECCCCceeeeEEEEEEeee----cCcEEEEEEcCCCccccCCCCCC
Confidence              0114556778888889999998 89999988886 4778888762    46889999987654444445564


No 51
>6FPJ_A Glutamate receptor 3; ligand-gated ion channel, membrane protein; HET: DMS, NAG, PO4; 1.96A {Rattus norvegicus}
Probab=99.62  E-value=2.4e-20  Score=201.38  Aligned_cols=372  Identities=13%  Similarity=0.153  Sum_probs=227.2  Template_Neff=11.900

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDL-LSNITLGVRILD-TCSRDTYALEQSLTFV  120 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~i-l~g~~l~~~~~d-~~~~~~~a~~~~~~~~  120 (908)
                      +++++||+++|.++.                ....|++.|++++|+++++ ++|+++++++.| +.+++..    ..+.+
T Consensus         3 ~~~i~Ig~~~~~~~~----------------~~~~~~~~a~~~~n~~g~~~~~g~~l~~~~~d~~~~~~~~----~~~~~   62 (390)
T 6FPJ_A            3 PNTISIGGLFMRNTV----------------QEHSAFRFAVQLYNTNQNTTEKPFHLNYHVDHLDSSNSFS----VTNAF   62 (390)
T ss_dssp             CSEEEEEEEEETTCH----------------HHHHHHHHHHHHHHTCCCTTTCSSEEEEEEEEESCSSHHH----HHHHH
T ss_pred             CceeEEEEeecCCCH----------------HHHHHHHHHHHHHHcCCCCCCCCceEEEEEEecCCCChHH----HHHHH
Confidence            568999999998752                4668999999999998765 357888888876 4444332    22233


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      .+++.                   +++++++|+.++..+..++..+...++|+|++.....     ..+++++++.|+  
T Consensus        63 ~~l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~p~--  116 (390)
T 6FPJ_A           63 CSQFS-------------------RGVYAIFGFYDQMSMNTLTSFCGALHTSFVTPSFPTD-----ADVQFVIQMRPA--  116 (390)
T ss_dssp             HHHHH-------------------HCCSCEEECCCTTTHHHHHHHHHHTTCCEEECSCCCS-----SCCSSEEECSCC--
T ss_pred             HHHhh-------------------CCeeEEEcCCCchhHHHHHHHHHhcCCceeeCCCCCC-----CCCCcEEEeecc--
Confidence            33322                   5788999998887777788888999999998775432     246788998887  


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                       +++++++++++++|+++++++++ .++....+.+++.+++. ++++......+. .+..++...+++++. .++++|++
T Consensus       117 -~~~~~~~~~~~~~~~~v~vl~~~-~~~~~~~~~~~~~~~~~-~~~v~~~~~~~~-~~~~~~~~~~~~l~~-~~~~~vv~  191 (390)
T 6FPJ_A          117 -LKGAILSLLSYYKWEKFVYLYDT-ERGFSVLQAIMEAAVQN-NWQVTARSVGNI-KDVQEFRRIIEEMDR-RQEKRYLI  191 (390)
T ss_dssp             -CHHHHHHHHHHTTCCEEEEEECS-TTCSHHHHHHHHHHHHH-TCEEEEEECTTC-CSHHHHHHHHHHHHH-TTCCEEEE
T ss_pred             -HHHHHHHHHHHcCCcEEEEEEeC-cccHHHHHHHHHHHHhC-CCeEEEEEeCCC-CCHHHHHHHHHHHhh-cCCcEEEE
Confidence             46788888888899999999954 67777777777777664 345433211110 122456667777763 57898888


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      ......+..+++++++.|+.. .+.|+..+.+...... ........+...+....               ...+....|
T Consensus       192 ~~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~~---------------~~~~~~~~f  255 (390)
T 6FPJ_A          192 DCEVERINTILEQVVILGKHSRGYHYMLANLGFTDILL-ERVMHGGANITGFQIVN---------------NENPMVQQF  255 (390)
T ss_dssp             ESCHHHHHHHHHHHHHHCSSSTTCEEEECCTTGGGCCC-HHHHHTTCEEEEEESCC---------------TTSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHhCCccCCeeEEEecCCcchhcH-HHHhcCCccEEEEEEec---------------CCCHHHHHH
Confidence            776677788899998888753 3556665433221100 00001111111111000               001111223


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~~~~-  434 (908)
                      .+.+++.+......         .+          ...+..++..+||+++++++|++++......    .....|... 
T Consensus       256 ~~~~~~~~~~~~~~---------~~----------~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~c~~~~  316 (390)
T 6FPJ_A          256 IQRWVRLDEREFPE---------AK----------NAPLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANP  316 (390)
T ss_dssp             HHHHTTSCTTTSTT---------SS----------SSCCCHHHHHHHHHHHHHHHHHHHHHHTTCCCCCC-----CCC--
T ss_pred             HHHHHhcCcccCCC---------CC----------CCCCChHHHHHHHHHHHHHHHHHHHHHcCCCcccCCCCCcccCCC
Confidence            23232222110000         00          0123456778999999999999988653210    001122110 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                        ...++..+.+.|++..|.|.+| ++.||++|++. ..+.+++++.    +.++.+|.|.....++.....|+
T Consensus       317 ~~~~~~~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~~i~~~~~----~~~~~vg~w~~~~~~~~~~~~~~  385 (390)
T 6FPJ_A          317 AVPWSQGIDIERALKMVQVQGMTG-NIQFDTYGRRTNYTIDVYEMKV----SGSRKAGYWNEYERFVPFSGTKH  385 (390)
T ss_dssp             CCCCTTHHHHHHHHHTCCEEETTE-EEEECTTSBEESCCEEEEEEET----TEEEEEEEEETTTEEEECC----
T ss_pred             CCcchhHHHHHHHHhcCCccCCCc-eEEECCCCceeeeEEEEEEeee----cCcEEEEEEcCCCccccCCCCCC
Confidence              0114556778888889999998 89999988886 4778888762    46889999987654444445564


No 52
>3H5L_A putative Branched-chain amino acid ABC; STRUCTURAL GENOMICS, TRANSPORTER, PSI-2, Protein; 1.7A {Ruegeria pomeroyi}
Probab=99.61  E-value=2.8e-20  Score=202.99  Aligned_cols=363  Identities=13%  Similarity=0.140  Sum_probs=230.2  Template_Neff=11.400

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD-TYALEQSLT  118 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~-~~a~~~~~~  118 (908)
                      ....++++||++.|.++...          ..+.....|++.|++++|+++++. |+++++.+.|+++++ ..    +.+
T Consensus         9 ~~~~~~i~Ig~i~~~~~~~~----------~~~~~~~~~~~~a~~~~n~~g~~~-g~~i~~~~~d~~~~~~~~----~~~   73 (419)
T 3H5L_A            9 AQSSDPVVIGCPAPLTGIVA----------ADGIEFQRGIQMAADEINAVGGIL-GRPIELVFADTQSKGVDV----VIQ   73 (419)
T ss_dssp             ----CCEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHTTTSBT-TBCEEEEEEECTTCCHHH----HHH
T ss_pred             cCCCCCEEEEEeecCCCCch----------hccHHHHHHHHHHHHHHHHcCCcC-CcceEEEEEeCCCCCHHH----HHH
Confidence            45678999999999876431          245678899999999999987654 788999888877653 22    233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA--PELS--DNTRYDFFSR  194 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~--~~l~--~~~~~~~~~~  194 (908)
                      .+++++.                  .++++++||+.++.....++..+.+.++|+|++....  +.+.  +...++++++
T Consensus        74 ~~~~l~~------------------~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  135 (419)
T 3H5L_A           74 SAQRLID------------------RDNASALIAGYNLENGTALHDVAADAGVIAMHANTVAVHDEMVKSDPDRYWGTFQ  135 (419)
T ss_dssp             HHHHHHH------------------TTCCSEEECSCCSSCSCHHHHHHHHHTCEEEECCCCHHHHHHHHHCTTTCTTEEE
T ss_pred             HHHHHHH------------------hcCCCEEEecccccchHHHHHHHHHcCCcEEeCCCchhcHHHHhcCccccCceee
Confidence            3343332                  1578999999888777788888899999999876422  2222  1123567889


Q NP_000836.2     195 VVPPDSYQAQAMVDIVTA--------LGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKII  266 (908)
Q Consensus       195 ~~~~~~~~~~~~~~~l~~--------~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~  266 (908)
                      +.++....+.++++++.+        .+|+++++++.++.++....+.+++.+++. ++++.....+.  ....++...+
T Consensus       136 ~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~  212 (419)
T 3H5L_A          136 YDPPETLYGGGFLKFLKDIEDNGEFSRPNNKIAIITGPGIYSVNIANAIRDGAGEY-GYDVSLFETVA--IPVSDWGPTL  212 (419)
T ss_dssp             SSCCTHHHHHHHHHHHHHHHHTTSCCCSSSEEEEEECSSHHHHHHHHHHHHHGGGG-TCEEEEEEECC--SSCSCCHHHH
T ss_pred             cCCChhHhHHHHHHHHHHHHhCCCCCCCCCeEEEEECCCHHHHHHHHHHHHHHHHc-CCEEEEEEeeC--CCCCCcHHHH
Confidence            999888888888888866        689999999977777888888888888765 45554332222  2234566677


Q NP_000836.2     267 KRLLETPNARAVIMFA-NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       267 ~~l~~~~~~~viv~~~-~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      ++++. .++++|++.+ .+..+..+++++++.|+..  .|++...+...... ........+.+....           +
T Consensus       213 ~~i~~-~~~~vv~~~~~~~~~~~~~~~~~~~~g~~~--~~~~~~~~~~~~~~-~~~~~~~~g~~~~~~-----------~  277 (419)
T 3H5L_A          213 AKLRA-DPPAVIVVTHFYPQDQALFMNQFMTDPTNS--LVYLQYGASLAAFR-DIAGDNSVGVTYATV-----------L  277 (419)
T ss_dssp             HHHHH-SCCSEEEECCCCHHHHHHHHHHHTTSCCSC--EEEECSGGGSHHHH-HHHGGGGTTCEEEES-----------S
T ss_pred             HHHHh-CCCCEEEEEeCChHHHHHHHHHHhhCCcCc--EEEEechhhhHHHH-HHHcccceeeEEEec-----------c
Confidence            77764 5788888775 4566778889988887742  34443322211100 000111222211110           0


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      .   ....+....|.+.+++.++.                          .....++..+|||+++++.+++....... 
T Consensus       278 ~---~~~~~~~~~f~~~~~~~~~~--------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~~~-  327 (419)
T 3H5L_A          278 G---TLQDEMGDAFAKAYKERYGD--------------------------LSSTASGCQTYSALYAYSIAAALAGGPGA-  327 (419)
T ss_dssp             C---CCSSHHHHHHHHHHHHHHCT--------------------------TSCHHHHHHHHHHHHHHHHHHHHTTSCCC-
T ss_pred             C---cCCCHHHHHHHHHHHHHHCC--------------------------CCCCcCcchHHHHHHHHHHHHHHcCCCCC-
Confidence            0   00011122233333322211                          01123466799999999999876543210 


Q NP_000836.2     426 GYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       426 ~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                           +  ....++..+.++|++..|.|.+| ++.||++|++...+.+..++..  ...+..|+.|..
T Consensus       328 -----~--~~~~~~~~l~~~l~~~~f~g~~G-~v~f~~~g~~~~~~~~~~~~~~--~~~~~~v~q~~~  385 (419)
T 3H5L_A          328 -----P--YDDVQNKAVADRLRSLIFRGPVG-TMRFHADTQSAWSYPTETNDPS--LGMPHIFSQIFD  385 (419)
T ss_dssp             -----T--TCHHHHHHHHHHHHHCEEEETTE-EEEBCTTTCBBCEETTTCSCTT--SSEECEEEECCC
T ss_pred             -----C--CCcccHHHHHHHHHhCCcccCCe-eEEeCCCCcccCCCCCcCCCcc--cccceEEEEeec
Confidence                 0  01234567888899889999999 8999999988777777776632  245778888886


No 53
>3H5L_B putative Branched-chain amino acid ABC; STRUCTURAL GENOMICS, TRANSPORTER, PSI-2, Protein; 1.7A {Ruegeria pomeroyi}
Probab=99.61  E-value=2.8e-20  Score=202.99  Aligned_cols=363  Identities=13%  Similarity=0.140  Sum_probs=232.5  Template_Neff=11.400

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRD-TYALEQSLT  118 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~-~~a~~~~~~  118 (908)
                      ....++++||++.|.++...          ..+.....|++.|++++|+++++. |+++++.+.|+++++ ..    +.+
T Consensus         9 ~~~~~~i~Ig~i~~~~~~~~----------~~~~~~~~~~~~a~~~~n~~g~~~-g~~i~~~~~d~~~~~~~~----~~~   73 (419)
T 3H5L_B            9 AQSSDPVVIGCPAPLTGIVA----------ADGIEFQRGIQMAADEINAVGGIL-GRPIELVFADTQSKGVDV----VIQ   73 (419)
T ss_dssp             CCCSSCEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHHTTTBT-TBCEEEEEEECTTCCHHH----HHH
T ss_pred             cCCCCCEEEEEeecCCCCch----------hccHHHHHHHHHHHHHHHHcCCcC-CcceEEEEEeCCCCCHHH----HHH
Confidence            45678999999999876431          245678899999999999987654 788999888877653 22    233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA--PELS--DNTRYDFFSR  194 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~--~~l~--~~~~~~~~~~  194 (908)
                      .+++++.                  .++++++||+.++.....++..+.+.++|+|++....  +.+.  +...++++++
T Consensus        74 ~~~~l~~------------------~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  135 (419)
T 3H5L_B           74 SAQRLID------------------RDNASALIAGYNLENGTALHDVAADAGVIAMHANTVAVHDEMVKSDPDRYWGTFQ  135 (419)
T ss_dssp             HHHHHHH------------------TTCCSEEECSCCSSCSCHHHHHHHHHTCEEEECCCCHHHHHHHHHCTTTCTTEEE
T ss_pred             HHHHHHH------------------hcCCCEEEecccccchHHHHHHHHHcCCcEEeCCCchhcHHHHhcCccccCceee
Confidence            3343332                  1578999999888777788888899999999876422  2222  1123567889


Q NP_000836.2     195 VVPPDSYQAQAMVDIVTA--------LGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKII  266 (908)
Q Consensus       195 ~~~~~~~~~~~~~~~l~~--------~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~  266 (908)
                      +.++....+.++++++.+        .+|+++++++.++.++....+.+++.+++. ++++.....+.  ....++...+
T Consensus       136 ~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~  212 (419)
T 3H5L_B          136 YDPPETLYGGGFLKFLKDIEDNGEFSRPNNKIAIITGPGIYSVNIANAIRDGAGEY-GYDVSLFETVA--IPVSDWGPTL  212 (419)
T ss_dssp             SSCCTHHHHHHHHHHHHHHHHTTSCCCSSSEEEEEECSSHHHHHHHHHHHHHGGGG-TCEEEEEEECC--SSCSCCHHHH
T ss_pred             cCCChhHhHHHHHHHHHHHHhCCCCCCCCCeEEEEECCCHHHHHHHHHHHHHHHHc-CCEEEEEEeeC--CCCCCcHHHH
Confidence            999888888888888866        689999999977777888888888888765 45554332222  2234566677


Q NP_000836.2     267 KRLLETPNARAVIMFA-NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       267 ~~l~~~~~~~viv~~~-~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      ++++. .++++|++.+ .+..+..+++++++.|+..  .|++...+...... ........+.+....           +
T Consensus       213 ~~i~~-~~~~vv~~~~~~~~~~~~~~~~~~~~g~~~--~~~~~~~~~~~~~~-~~~~~~~~g~~~~~~-----------~  277 (419)
T 3H5L_B          213 AKLRA-DPPAVIVVTHFYPQDQALFMNQFMTDPTNS--LVYLQYGASLAAFR-DIAGDNSVGVTYATV-----------L  277 (419)
T ss_dssp             HHHHH-SCCSEEEECCCCHHHHHHHHHHHTTSCCSC--EEEECSGGGSHHHH-HHHGGGGTTCEEEES-----------S
T ss_pred             HHHHh-CCCCEEEEEeCChHHHHHHHHHHhhCCcCc--EEEEechhhhHHHH-HHHcccceeeEEEec-----------c
Confidence            77764 5788888775 4566778889988887742  34443322211100 000111222211110           0


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      .   ....+....|.+.+++.++.                          .....++..+|||+++++.+++....... 
T Consensus       278 ~---~~~~~~~~~f~~~~~~~~~~--------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~~~-  327 (419)
T 3H5L_B          278 G---TLQDEMGDAFAKAYKERYGD--------------------------LSSTASGCQTYSALYAYSIAAALAGGPGA-  327 (419)
T ss_dssp             C---CCSSHHHHHHHHHHHHHHCT--------------------------TSCHHHHHHHHHHHHHHHHHHHHTTSCCC-
T ss_pred             C---cCCCHHHHHHHHHHHHHHCC--------------------------CCCCcCcchHHHHHHHHHHHHHHcCCCCC-
Confidence            0   00011122233333322211                          01123466799999999999876543210 


Q NP_000836.2     426 GYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       426 ~~~~~~~~~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                           +  ....++..+.++|++..|.|.+| ++.||++|++...+.+..++..  ...+..|+.|..
T Consensus       328 -----~--~~~~~~~~l~~~l~~~~f~g~~G-~v~f~~~g~~~~~~~~~~~~~~--~~~~~~v~q~~~  385 (419)
T 3H5L_B          328 -----P--YDDVQNKAVADRLRSLIFRGPVG-TMRFHADTQSAWSYPTETNDPS--LGMPHIFSQIFD  385 (419)
T ss_dssp             -----T--TCHHHHHHHHHHHHHCEEEETTE-EEEBCTTTCBBCEETTTCSCTT--SSEECEEEECSC
T ss_pred             -----C--CCcccHHHHHHHHHhCCcccCCe-eEEeCCCCcccCCCCCcCCCcc--cccceEEEEeec
Confidence                 0  01234567888899889999999 8999999988777777776632  245778888886


No 54
>5KCA_A Cerebellin-1,Cerebellin-1,Cerebellin-1,Glutamate receptor ionotropic, delta-2; Cerebellin, ionotropic glutamate receptor (iGluR); 3.1A {Homo sapiens}
Probab=99.60  E-value=4.6e-20  Score=221.09  Aligned_cols=382  Identities=16%  Similarity=0.223  Sum_probs=236.7  Template_Neff=10.400

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI-LDTCSRDTYALEQSLT  118 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~-~d~~~~~~~a~~~~~~  118 (908)
                      .....+++||+++|.++                .....|+++|++++|+++++++++++++++ .|++.++..+.+    
T Consensus       452 ~~~~~~i~IG~i~~~sg----------------~~~~~a~~~A~~~iN~~~~~~~g~~l~~~~~~D~~~~~~~a~~----  511 (878)
T 5KCA_A          452 GGSDSIIHIGAIFDESA----------------KKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQ----  511 (878)
T ss_pred             CCCCCCeEEEEEeCCCh----------------HHHHHHHHHHHHHHHhCCCCCCCCeEEEEEEEeCCCCHHHHHH----
Confidence            34467889999998764                246689999999999987777788899888 888776543333    


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAP-------ELSDNTRYDF  191 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~-------~l~~~~~~~~  191 (908)
                      .+++++.                   ++++++||+.++.....++.+++..++|+|++....+       .+++...+++
T Consensus       512 ~~~~l~~-------------------~~v~aviG~~~s~~~~~v~~~~~~~~ip~is~~~~~~~~~~~~~~l~~~~~~~~  572 (878)
T 5KCA_A          512 EACELMN-------------------QGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDD  572 (878)
T ss_pred             HHHHHHH-------------------cCCCEEECCCCChhHHHHHHHHHHhCCCEEccCCCCCCCCCCCcccCCCCCCCc
Confidence            3333332                   4788999998887777888889999999999876554       3443345788


Q NP_000836.2     192 FSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL-  270 (908)
Q Consensus       192 ~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~-  270 (908)
                      +++..+++..+++++++++++++|+++++++ +++++....+.+++.+++. ++++.....++  ....++...+++++ 
T Consensus       573 ~~~~~~~~~~~~~al~~~l~~~~w~~v~Iv~-d~~~g~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~~~~  648 (878)
T 5KCA_A          573 YTLSVRPPVYLHDVILRVVTEYAWQKFIIFY-DSEYDIRGIQEFLDKVSQQ-GMDVALQKVEN--NINKMITTLFDTMRI  648 (878)
T ss_pred             eeecCCCHHHHHHHHHHHHHHhCCCEEEEEe-cChhhHHHHHHHHHHHHHc-CCEEEEeeecC--CCCCCChHHHHHHHH
Confidence            9999998888899999999889999999777 4567777778888777765 45554332222  11122222222221 


Q NP_000836.2     271 ---E--TPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRY  344 (908)
Q Consensus       271 ---~--~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~  344 (908)
                         +  ..++++|++......+..+++++++.++.. ++.|+..+.+...............+.........        
T Consensus       649 ~~l~~~~~~~~vIil~~~~~~~~~~l~~a~~~g~~~~~~~~i~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~--------  720 (878)
T 5KCA_A          649 EELNRYRDTLRRAILVMNPATAKSFITEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTFP--------  720 (878)
T ss_pred             HHHHhhccCCcEEEEeCCHHHHHHHHHHHHHcCCCCCCcEEEEeccccCCcchhHHHHHhccceeeecCCCC--------
Confidence               0  136788888777777888999999888753 46777765443221100000000111111100000        


Q NP_000836.2     345 FRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLC  424 (908)
Q Consensus       345 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~  424 (908)
                           .........+.+.+.+.+.              .|......    ...+..++..+|||++++++|++++....+
T Consensus       721 -----~~~~~~~~~~~~~~~~~~~--------------~~~~~~~~----~~~~~~~~~~~yDAv~l~a~al~~~~~~~~  777 (878)
T 5KCA_A          721 -----VPQNISQRCFRGNHRISST--------------LCDPKDPF----AQNMEISNLYIYDTVLLLANAFHKKLEDRK  777 (878)
T ss_pred             -----CCCChhHHhhhhhhccCCC--------------CCCCCCCC----CCCccchHHHHHHHHHHHHHHHHHHHhcCC
Confidence                 0000001111111111110              11100000    012345677899999999999999875432


Q NP_000836.2     425 PGY--IGLCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITN-KSTEYKVIGHWTNQLH  496 (908)
Q Consensus       425 ~~~--~~~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~-~~~~~~~Vg~~~~~~~  496 (908)
                      ...  ...|...   ...++..+.+.|++..|.|.+| .+.||++|++. ..+.|++++... +...+++||.|.....
T Consensus       778 ~~~~~~~~c~~~~~~~~~~~~~l~~~l~~~~f~G~~G-~i~fd~~g~r~~~~~~I~~~~~~~~~~~~~~~Vg~w~~~~g  855 (878)
T 5KCA_A          778 WHSMASLSCIRKNSKPWQGGRSMLETIKKGGVSGLTG-ELEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVTG  855 (878)
T ss_pred             CCCCCCCccCCCCCCCCcCHHHHHHHHhcCeeecCCc-cEEecCCCCcCCCeEEEEEEecCCCCCCceEEEEEEeCCCC
Confidence            110  1122110   1124556788888889999998 89999999964 578888887411 1257899999997643


No 55
>4XFK_A BrovA.17370.a; transport protein, Structural Genomics, Seattle; 1.3A {Brucella ovis}
Probab=99.60  E-value=5.4e-20  Score=199.14  Aligned_cols=355  Identities=14%  Similarity=0.144  Sum_probs=229.2  Template_Neff=11.000

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ...++||++.|++++..          ..+..+..|+++|++++|+.+++. |+++++.+.|+++++..+    .+.+++
T Consensus         9 ~~~~~ig~~~plsG~~~----------~~g~~~~~g~~~a~~~iN~~gg~~-g~~i~~~~~d~~~~~~~~----~~~~~~   73 (399)
T 4XFK_A            9 AEPLKIALVETLSGPQA----------STGLLYRAAVLYQLGKINEAGGFN-GEKIQILEYDNQGGPVGA----ADRVKA   73 (399)
T ss_dssp             CCCCEEEEEECCSSTTC----------HHHHHHHHHHHHHHHHHHHTTCBT-TBCCEEEEEECCSHHHHH----HHHHHH
T ss_pred             CCCceEEEEcCCCCCch----------HHHHHHHHHHHHHHHHHHHcCCcC-CeeEEEEEEeCCCChHHH----HHHHHH
Confidence            45789999999998642          356788999999999999887653 788999999987764432    233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRL-------FKIPQISYASTAPELSDNTRYDFFSRV  195 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~-------~~iP~Is~~~~~~~l~~~~~~~~~~~~  195 (908)
                      ++.                   ++++++||+.++.....++..++.       .++|+|++.+..+.+.+...+++++++
T Consensus        74 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~  134 (399)
T 4XFK_A           74 AIA-------------------DGAQIIVQGSSSAVAGQITEDVRKYNLRNKGKEVLYLNLGAEALELTGSKCHFYHFRF  134 (399)
T ss_dssp             HHH-------------------TTCSEEEECSCHHHHHHHHHHHHHHHHHSTTSCCEEEESSCCCGGGGTTTCCTTEEEC
T ss_pred             HHH-------------------cCCCEEEEcCChHHHHHHHHHHHHhccccCCCceeEEeccccchHhcCCCCCceEEEc
Confidence            332                   478899998877766666666665       589999877655544332246788999


Q NP_000836.2     196 VPPDSYQAQAMVDIVTALGW--NYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETP  273 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~~~--~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~  273 (908)
                      .++....+.++++++.+.+|  +++++++.+++++....+.+++.+++. ++++.....+.. ....++...+++++. .
T Consensus       135 ~~~~~~~~~~~~~~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~-~~~~~~~~~~~~i~~-~  211 (399)
T 4XFK_A          135 SPNAAIRFKTVAQGMKDKGILGERAYSINQNYSWGVDVENTVVANAKEI-GYEVVDKTLHEV-NKIQDFSPYVAKIQA-A  211 (399)
T ss_dssp             SCCHHHHHHHHHHHHHHHTCCCSEEEEEEESSHHHHHHHHHHHHHCCCC-CCEEEEEEEECS-SCCSCCHHHHHHHHH-T
T ss_pred             CCcHHHHHHHHHHHHHHcCCCCceEEEEeeCChhhhhHHHHHHHHHHHc-CCEEeeeeeccc-ccCcccHHHHHHHHH-C
Confidence            99988888899999888888  899999977778888888888887765 355543322221 123456667777764 5


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANN  353 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~  353 (908)
                      ++|+|++...+..+..+++++++.|+..  .|+. . +...............+.+......          ..   ...
T Consensus       212 ~~~~iv~~~~~~~~~~~~~~~~~~g~~~--~~~~-~-~~~~~~~~~~~~~~~~~~~~~~~~~----------~~---~~~  274 (399)
T 4XFK_A          212 NVDTVFTGNWSNDLLLLMKAASGAGLKA--KFAT-S-FLDQPGNIGNAGAIAEGHIVSTPFN----------PE---ANG  274 (399)
T ss_dssp             TCSEEEECCCTHHHHHHHHHHHHHTCCS--EEEE-S-STTSTTHHHHHGGGCTTCEEEESCC----------TT---TTH
T ss_pred             CCCEEEEecCCHHHHHHHHHHHHcCCcc--cccc-c-cccCcchHHhchHhhcCcEEecCCC----------cc---cCC
Confidence            8899988877777888999998888753  3443 2 2111100000111122322211100          00   001


Q NP_000836.2     354 RRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPR  433 (908)
Q Consensus       354 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~  433 (908)
                      +....|.+.+.+.++                           ..++.++..+|||+++++++++++....          
T Consensus       275 ~~~~~f~~~~~~~~~---------------------------~~p~~~~~~~yda~~~l~~al~~~~~~~----------  317 (399)
T 4XFK_A          275 EASMAFAEDYKKVTG---------------------------HYPSYVEPAAVFGLQLFGEALKNVKPGE----------  317 (399)
T ss_dssp             HHHHHHHHHHHHHHS---------------------------SCCCTTHHHHHHHHHHHHHHHHHSCCCS----------
T ss_pred             HHHHHHHHHHHHHHC---------------------------CCCCchHHHHHHHHHHHHHHHHhcCCCC----------
Confidence            111222222222211                           1123467789999999999998875311          


Q NP_000836.2     434 MSTIDGKELLGYIRAVNFNGSAGTPVTFNE-NGDAPGRYDIFQYQITNKSTEYKVIG-HWTN  493 (908)
Q Consensus       434 ~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~-~G~~~~~~~i~~~~~~~~~~~~~~Vg-~~~~  493 (908)
                       ...+++.+.++|++..|.|.+| .+.|+. ++++...+.+.+++..   +....+| .|..
T Consensus       318 -~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~i~~~~~~---~~~~~~g~~~~~  374 (399)
T 4XFK_A          318 -GKINTTDIALAIENASVKTPMG-DYSMRSDDHQAKFPMVVQEVSKK---ARIKADGTEYGF  374 (399)
T ss_dssp             -SCCCHHHHHHHHHHCEEEETTE-EEEECTTTCBEECCEEEEEEETT---CSSBSTTSSCEE
T ss_pred             -CCCCHHHHHHHHHhCceecCce-eeEeCCCCCeeeecEEEEEEcCc---ccccCCCCccee
Confidence             0124567788888888999988 899997 5555567788888732   3455667 6653


No 56
>5KC9_A Glutamate receptor ionotropic, delta-1; ionotropic glutamate receptor (iGluR), neurotransmission; HET: BU1, CL, NAG, EDO, PG4; 2.3A {Mus musculus}
Probab=99.60  E-value=5.6e-20  Score=201.24  Aligned_cols=372  Identities=16%  Similarity=0.202  Sum_probs=224.4  Template_Neff=11.600

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTFV  120 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~~  120 (908)
                      .+.+++||+++|.++.                ....|+++|++++|+++++++++++++.+.|++ +++..+.    +.+
T Consensus         3 ~~~~i~Ig~l~p~~g~----------------~~~~~~~~A~~~in~~~~~~~~~~l~~~~~d~~~~~~~~~~----~~~   62 (428)
T 5KC9_A            3 GDSIIHIGAIFEENAA----------------KDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAV----QEA   62 (428)
T ss_dssp             --CEEEEEEEEESSCH----------------HHHHHHHHHHHHHHHHCSSSTTCEEEEEEEEECTTCHHHHH----HHH
T ss_pred             CCceeEEEEeecCCCh----------------HHHHHHHHHHHHHhcCCccCCCceEEEEEEEecCCCHHHHH----HHH
Confidence            4578999999998752                466899999999999877766788998888864 4433222    233


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      .+++.                   ++++++||+.++..+..++.++...++|+|++.. ++.+.  ..+++++++.++..
T Consensus        63 ~~l~~-------------------~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~-~~~~~--~~~~~~~~~~~~~~  120 (428)
T 5KC9_A           63 CDLMT-------------------QGILALVTSTGCASANALQSLTDAMHIPHLFVQR-NPGGS--PRTACHLNPSPDGE  120 (428)
T ss_dssp             HHHHH-------------------TCCSCEEEECCHHHHHHHHHHHHHHTCCEEECCC-CSTTS--CCCCCCCCCCCTTC
T ss_pred             HHHHh-------------------cCeeEEEcCCChHHHHHHHHHHHhcCCCEeeeec-CCCCC--CCcccceecCCCCC
Confidence            33332                   5789999998887777888889999999999854 33332  23456666555544


Q NP_000836.2     201 ----------YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFE-------  263 (908)
Q Consensus       201 ----------~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~-------  263 (908)
                                ..+.++++++++++|+++++++.+ +++....+.+.+.+++. ++++.......  .+..++.       
T Consensus       121 ~~~~~~~p~~~~~~a~~~~l~~~~~~~v~il~~~-~~g~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~~~  196 (428)
T 5KC9_A          121 AYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDS-EYDIRGLQSFLDQASRL-GLDVSLQKVDK--NISHVFTSLFTTMK  196 (428)
T ss_dssp             CCEEECSCCCCHHHHHHHHHHHTTCSEEEEEECT-TCCGGGGHHHHHHHHHT-TCEEEEEECCS--CHHHHHHHHHHHSC
T ss_pred             cceeccCCChhHHHHHHHHHHHcCCcEEEEEEcC-hHHHHHHHHHHHHHHhh-CCcEEEEEcCC--CcccccHHHHHHhh
Confidence                      578888998888899999999954 46777777777777665 35554322111  1111222       


Q NP_000836.2     264 -KIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEG-AVTILPKRASIDG  340 (908)
Q Consensus       264 -~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g-~~~~~~~~~~~~~  340 (908)
                       ..+++++.  .+++|++......+..+++++++.|+.. .+.|+..+.+...... ........+ ...+..       
T Consensus       197 ~~~l~~l~~--~~~~iv~~~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~-------  266 (428)
T 5KC9_A          197 TEELNRYRD--TLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEI-LDLVHSALGRMTVVRQ-------  266 (428)
T ss_dssp             HHHHHHHHH--HTTEEEEESCHHHHHHHHHHHHHTTCCCTTCEEEEECSCCCHHHH-HHHHHHCSSEEEEEEE-------
T ss_pred             HHHHHHHhh--cccEEEEECCHHHHHHHHHHHHHcCCCCCCeEEEEecCCcCCccH-HHHHhccCcceEEEEe-------
Confidence             44555542  3788877777777888999998888754 3566665432211100 000000111 111100       


Q NP_000836.2     341 FDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH  420 (908)
Q Consensus       341 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~  420 (908)
                         + .    ...+....|.+.+.+.+..             .|.....    ....+..++..+|||++++++|++++.
T Consensus       267 ---~-~----~~~~~~~~f~~~~~~~~~~-------------~~~~~~~----~~~~~~~~~~~~yda~~~~~~al~~~~  321 (428)
T 5KC9_A          267 ---I-F----PSAKDNQKCMRNNHRISSL-------------LCDPQEG----YLQMLQISNLYLYDSVLMLANAFHRKL  321 (428)
T ss_dssp             ---C-C----CCCCCTTTTEETTEECCST-------------TTSCCTT----TGGGSCHHHHHHHHHHHHHHHHHHHHH
T ss_pred             ---c-C----CCchHHHHHHHHHHHchhh-------------hcCCCCC----cchhcccHHHHHHHHHHHHHHHHHHHH
Confidence               0 0    0011112222223222210             0100000    001234567889999999999999886


Q NP_000836.2     421 KDLCPG--YIGLCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITN-KSTEYKVIGHWTN  493 (908)
Q Consensus       421 ~~~~~~--~~~~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~-~~~~~~~Vg~~~~  493 (908)
                      ...+..  ....|...   ...++..+.+.|++..|.|.+| .+.|+++|++. ..+.+++++... +...++.||.|+.
T Consensus       322 ~~~~~~~~~~~~c~~~~~~~~~~~~~l~~~l~~~~~~g~~G-~v~f~~~g~~~~~~~~i~~~~~~~~~~~~~~~vg~w~~  400 (428)
T 5KC9_A          322 EDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTG-VMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDS  400 (428)
T ss_dssp             HTTCCCCCCCCCSSSTTCCCCTTHHHHHHHHHTCEEEETTE-EEECCTTSBCCCCEEEEEEEEEETTTEEEEEEEEEEET
T ss_pred             HcCCCCCcCCCcccCCCCCCCcchHHHHHHHHcCeeecccc-eEEECCCCCCCeEEEEEEeceeeccCCCCeEEEEEEeC
Confidence            532110  01122110   1124556778888888999999 89999999886 578888877421 1256899999997


Q NP_000836.2     494 QL  495 (908)
Q Consensus       494 ~~  495 (908)
                      ..
T Consensus       401 ~~  402 (428)
T 5KC9_A          401 EK  402 (428)
T ss_dssp             TT
T ss_pred             CC
Confidence            64


No 57
>6JFY_A Glutamate receptor ionotropic, kainate 3; Glutamate receptor, Kainate, SYM, MEMBRANE; 7.4A {Rattus norvegicus}
Probab=99.58  E-value=1.1e-19  Score=216.68  Aligned_cols=373  Identities=15%  Similarity=0.201  Sum_probs=238.9  Template_Neff=11.400

Q NP_000836.2      43 DGDIILGGLFPVHAK-GERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTFV  120 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~-~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~~  120 (908)
                      +++++||+++|.++. ..          ..+.....|+++|++++|+.+++++|+++++++.|++ +++..+    .+.+
T Consensus         2 ~~~i~ig~~~~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~~~~~~g~~l~l~~~d~~~~~~~~~----~~~~   67 (809)
T 6JFY_A            2 PHVIRIGGIFEYADGPNA----------QVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEA----TKKA   67 (809)
T ss_dssp             -CEEECCBCEEESSGGGC----------SSCCHHHHHHHHHHHHHHHCTTSCSSCEEECCCCEEESSCHHHH----HHHH
T ss_pred             CceeEEEEeeecCCCCcc----------ccccHHHHHHHHHHHHHhcCCccCCCceeEEeeEecCCCChHHH----HHHH
Confidence            468999999999864 21          3567889999999999999887777889999999977 453322    2233


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   +++++++|+.++..+.++++.++..++|++++.++++.+.+  ..++++++.|++.
T Consensus        68 ~~l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~  126 (809)
T 6JFY_A           68 CDQLA-------------------LGVVAIFGPSQGSTTNAVQSICNALEVPHIQLRWKHHPLDN--KDTFYVNLYPDYA  126 (809)
T ss_dssp             HHHHH-------------------HCCSCCBCCSCTTTHHHHHHHHHHTTCCCBCCSCCCCCSSC--CCSSCCCCCCCHH
T ss_pred             HHHHh-------------------cCccEEECCCCchHHHHHHHHHHHhCCCEEEEEecCCCCCC--CCeEEEEeeCCHH
Confidence            33322                   47899999888877778888889999999998876665443  2577899999999


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ..++++++++++++|+++++++ +++++....+.+++.+++. ++++.... +.  .+..++...++++++ .++|+|++
T Consensus       127 ~~~~~~~~~l~~~~~~~v~iv~-~~~~~~~~~~~~~~~~~~~-g~~v~~~~-~~--~~~~~~~~~~~~l~~-~~~~~vv~  200 (809)
T 6JFY_A          127 SLSHAILDLVQSLKWRSATVVY-DDSTGLIRLQELIMAPSRY-NIRLKIRQ-LP--IDSDDSRPLLKEMKR-GREFRIIF  200 (809)
T ss_dssp             HHHHHHHHHHHHHTCSCCCEEE-CSTHHHHHHHHHHTGGGTS-CCCCCEEE-CC--SSSCCCHHHHHHHHH-TTCCEEEE
T ss_pred             HHHHHHHHHHHHcCCCEEEEEE-cCCchHHHHHHHhhCcccc-CeeEEEEe-CC--CCCcccHHHHHHHHh-CCceEEEE
Confidence            9999999999888999999999 6778888888888888775 46665433 22  223456677777763 57899888


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      .+....+..++++++++|+.. .+.|+..+.+...... ........+......          + .    ...+....|
T Consensus       201 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~----------~-~----~~~~~~~~f  264 (809)
T 6JFY_A          201 DCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDL-EPYRYSGVNLTGFRI----------L-N----VDNPHVSAI  264 (809)
T ss_dssp             CSCHHHHHHHHHHHHHTTCCCTTCEEECCSSCTTSSCC-HHHHTTCCEEECCBC----------S-C----TTCHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHccCcCCCeEEEEeeCCcccCCC-cccccCCceeEEEEE----------e-e----CCCchHHHH
Confidence            877777888999999888754 3456654432211100 000000011110000          0 0    001111122


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM-STID  438 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~-~~~~  438 (908)
                      .+.+++.+.....         ..|...      ....++.++..+|||++++++|++++....+..  ..|... ...+
T Consensus       265 ~~~~~~~~~~~~~---------~~~~~~------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~--~~~~~~~~~~~  327 (809)
T 6JFY_A          265 VEKWSMERLQAAP---------RAESGL------LDGVMMTDAALLYDAVHIVSVTYQRAPQMTVNS--LQCHRHKAWRF  327 (809)
T ss_dssp             HHHHHHHCCC--------------------------CCCCHHHHHHHHHHHHHHHHHHSSCCCCCCC--CCSSSCCCCHH
T ss_pred             HHHhhHHHHhhCC---------cccCCc------CCCCcchHHHHHHHHHHHHHHHHHhCcCCCCcc--ccccccccccc
Confidence            2222222110000         000000      001234567889999999999999987532111  111111 1124


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDA-P-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~-~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ++.+.++|++..|.|.+| ++.||++|++ . ..+.+.+++    ++.++.+|.|.+.
T Consensus       328 ~~~l~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~~i~~~~----~~~~~~v~~~~~~  380 (809)
T 6JFY_A          328 GGRFMNFIKEAQWEGLTG-RIVFNKTSGLRTDFDLDIISLK----EDGLEKVGVWSPA  380 (809)
T ss_dssp             HHHHHHHHHTCCEEETTE-EECCBTTTTBCCCCCEEEEEEE----TTEEEEEEEEETT
T ss_pred             hhHHHHHHHHhccCCCcc-cEEEecCCCceeeeEEEEEEec----ccCceEeEEEeCC
Confidence            567888888889999988 8999986443 3 266777776    2568888988764


No 58
>4GPA_A Glutamate receptor 4; PBP fold, GLUTAMATE RECEPTOR, LIGAND-GATED; HET: NAG; 2.25A {Rattus norvegicus}
Probab=99.58  E-value=1.1e-19  Score=196.06  Aligned_cols=361  Identities=14%  Similarity=0.180  Sum_probs=224.0  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLL-SNITLGVRI-LDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il-~g~~l~~~~-~d~~~~~~~a~~~~~~~~  120 (908)
                      +++++||+++|.++.                ....|+++|++++|+++++. +++++++.+ .|+.+++..    ..+.+
T Consensus         3 ~~~i~ig~~~~~~~~----------------~~~~~~~~a~~~~n~~~~~~~~~~~l~~~~~~~~~~~~~~----~~~~~   62 (389)
T 4GPA_A            3 PSSVQIGGLFIRNTD----------------QEYTAFRLAIFLHNTSPNASEAPFNLVPHVDNIETANSFA----VTNAF   62 (389)
T ss_dssp             CSEEEEEEEECTTCH----------------HHHHHHHHHHHHHHTCSCTTTCSSEEEEEEEECSSCCHHH----HHHHH
T ss_pred             CCceeeeeEEecCCH----------------HHHHHHHHHHHHHhcCCCcCCCCceeeeeeeecCCCCHHH----HHHHH
Confidence            568999999998752                56789999999999876542 346777664 344444332    22333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      .+++.                   +++++|||+.++.....++.++...+||+|++.+..+     ..+++++++.++  
T Consensus        63 ~~~~~-------------------~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~--  116 (389)
T 4GPA_A           63 CSQYS-------------------RGVFAIFGLYDKRSVHTLTSFCSALHISLITPSFPTE-----GESQFVLQLRPS--  116 (389)
T ss_dssp             HHHHH-------------------TTCSEEEECCCTTTHHHHHHHHHHTTCEEEECSCCCS-----SCCSSEEECSCC--
T ss_pred             HHHHh-------------------hCeeEEEeCCCchHHHHHHHHHHHcCCcEEeCCCCCC-----CCcccEEEeecc--
Confidence            33332                   4788999988777777788888999999999876543     236788888887  


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                       .+.++++++++++|+++++++.++ ++....+.+++.+++. ++++.......  .+..++...+++++. .++++|++
T Consensus       117 -~~~~~~~~~~~~~~~~v~il~~~~-~~~~~~~~~~~~~~~~-~~~v~~~~~~~--~~~~~~~~~~~~i~~-~~~~~vv~  190 (389)
T 4GPA_A          117 -LRGALLSLLDHYEWNCFVFLYDTD-RGYSILQAIMEKAGQN-GWHVSAICVEN--FNDVSYRQLLEELDR-RQEKKFVI  190 (389)
T ss_dssp             -CHHHHHHHHHHTTCCEEEEEECST-TCSHHHHHHHHHHHTT-TCEEEEEECTT--CCHHHHHHHHHHHHH-HTCCEEEE
T ss_pred             -hHHHHHHHHHHcCCcEEEEEEcCh-hHHHHHHHHHHHHhhc-CCeEEEEEeeC--CCCccHHHHHHHHHh-cCCcEEEE
Confidence             567788888888999999999655 7777778888877765 35554321111  122345566777763 57898888


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      .+....+..+++++++.|+.. .+.|+..+.+...... ........+......           ..    ...+....|
T Consensus       191 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~-----------~~----~~~~~~~~f  254 (389)
T 4GPA_A          191 DCEIERLQNILEQIVSVGKHVKGYHYIIANLGFKDISL-ERFIHGGANVTGFQL-----------VD----FNTPMVTKL  254 (389)
T ss_dssp             ECCHHHHHHHHHHHHHHTCSBTTCEEEECSSBGGGSCC-HHHHHHBCEEEEEEC-----------SC----TTSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHcCCCCCCeEEEEEcCCccccCh-HHhccCCeeEEEEEE-----------ec----CCCHHHHHH
Confidence            776667788999998888753 3556665432211100 000000111111100           00    001111223


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~~~~-  434 (908)
                      .+.|++.++..             |...       ...+..++..+||++++++++++++....+.    .....|... 
T Consensus       255 ~~~~~~~~~~~-------------~~~~-------~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~c~~~~  314 (389)
T 4GPA_A          255 MDRWKKLDQRE-------------YPGS-------ETPPKYTSALTYDGVLVMAETFRSLRRQKIDISRRGNAGDCLANP  314 (389)
T ss_dssp             HHHHTTSCTTT-------------STTT-------TSCCCHHHHHHHHHHHHHHHHHHHHHHTTCCCCCTTCCCCTTCSS
T ss_pred             HHHHHHhcccc-------------CCCC-------CCCCCcHHHHHHHHHHHHHHHHHHHHhCCCCcccCCCCCccccCC
Confidence            33333322210             0000       0113456778999999999999987643211    001122210 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQLH  496 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~~  496 (908)
                        ...++..+.+.|++..|.|.+| ++.|+++|++.. .+.+++++    ++.++.||.|+....
T Consensus       315 ~~~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~g  374 (389)
T 4GPA_A          315 AAPWGQGIDMERTLKQVRIQGLTG-NVQFDHYGRRVNYTMDVFELK----STGPRKVGYWNDMDK  374 (389)
T ss_dssp             CCCCTTHHHHHHHHHTCEEEETTE-EEEBCTTSCBCSCEEEEEEEE----TTEEEEEEEEETTTE
T ss_pred             CCcccchHHHHHHHhcCCcccCCe-eeEECCCCceeeeeEEEEEcc----cCCCEEeEEEeCCcc
Confidence              1124556778888888999988 899999898875 78888887    246889999987643


No 59
>5EWM_A NMDA glutamate receptor subunit, Glutamate; Glutamate receptor, allosteric modulator, GluN2B; HET: MAN, 5SM, NAG, BMA; 2.76A {Xenopus laevis}
Probab=99.58  E-value=1.2e-19  Score=195.95  Aligned_cols=351  Identities=18%  Similarity=0.242  Sum_probs=221.3  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.+                  ....|+++|++++|+.++ +.++++++...|+..++..+.    +.+.+
T Consensus         2 ~~~i~Ig~~~~~~------------------~~~~~~~~a~~~~n~~~~-~~~~~l~~~~~d~~~~~~~~~----~~~~~   58 (390)
T 5EWM_A            2 PKIVNIGAVLSTK------------------KHEQIFREAVNQANKRHF-TRKIQLQATSVTHRPNAIQMA----LSVCE   58 (390)
T ss_dssp             CEEEEEEEEESSH------------------HHHHHHHHHHHHHHHHSC-CSSEEEEEEEEECCSSHHHHH----HHCCC
T ss_pred             CcceEEEEEeCch------------------hHHHHHHHHHHHHhhhcC-CCCceEEEEEecCCCCHHHHH----HHHHH
Confidence            4678999999875                  245789999999998753 356778877666555433222    22222


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAA-----ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-----~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      ++.                  .+++++++|+.     ++..+..++.++...++|+|++.+..+.+++...+++++++.+
T Consensus        59 ~~~------------------~~~v~~vig~~~~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~  120 (390)
T 5EWM_A           59 DLI------------------SSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP  120 (390)
T ss_dssp             CCG------------------GGTEEEEEECCCC-----CCSHHHHHHHHHTTCCEEESSCCCGGGGCTTTSTTEEESSC
T ss_pred             HHh------------------hcCcEEEEECCCCCCCCCCCchHHHHHHHhcCCCEEEccCCCcccccccccceEEecCC
Confidence            221                  15788999873     3344455677888899999998887766654445788999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQS-------QKIP------------REPR  258 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~-------~~~~------------~~~~  258 (908)
                      +...++.++++++++++|+++++++.++.++....+.+++.+++. ++++...       ..+.            ...+
T Consensus       121 ~~~~~~~~~~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  199 (390)
T 5EWM_A          121 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEGK-ESKSKKRNYENLDQLSYDNKRGPKADKVLQFEPG  199 (390)
T ss_dssp             CGGGGHHHHHHHHHHHTCCEEEEEEESSHHHHHHHHHHHHHHCC------------------------CEEEEEEEECTT
T ss_pred             CHHHHHHHHHHHHHHcCCCEEEEEEecCCcchHHHHHHHHHHhcC-CccccccccccccccccccCCCCCcccceecCCC
Confidence            998889999999988999999999987778888888888877765 3443210       0000            0011


Q NP_000836.2     259 PGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRAS  337 (908)
Q Consensus       259 ~~~~~~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~  337 (908)
                      ..++...+++++. .++|+|++.........+++++++.++.. ++.|+..+.+.....    ......+.+.       
T Consensus       200 ~~~~~~~~~~l~~-~~~~~ii~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~----~~~~~~~~~~-------  267 (390)
T 5EWM_A          200 TKNLTALLLEAKE-LEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSA----LRYAPDGIIG-------  267 (390)
T ss_dssp             CSCCHHHHHHHHH-SSCCEEEEECCHHHHHHHHHHHHHTTCSSTTCEEECCSGGGSHHH----HHHCCTTCEE-------
T ss_pred             chhHHHHHHHHHh-CCCeEEEEECCHHHHHHHHHHHHHcCCCCCCEEEEEecccCCcch----hhcCCCeEEE-------
Confidence            2345556666663 57899888776667778888888877743 456776543321100    0000000000       


Q NP_000836.2     338 IDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALH  417 (908)
Q Consensus       338 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~  417 (908)
                                           + .    .                             ..+..++..+|||++++++|++
T Consensus       268 ---------------------~-~----~-----------------------------~~~~~~~~~~ydav~~~~~al~  292 (390)
T 5EWM_A          268 ---------------------L-Q----L-----------------------------INGKNESAHISDAVAVVAQAIH  292 (390)
T ss_dssp             ---------------------E-E----E-----------------------------TTTTCHHHHHHHHHHHHHHHHH
T ss_pred             ---------------------E-E----E-----------------------------cCCCchHHHHHHHHHHHHHHHH
Confidence                                 0 0    0                             0112356789999999999999


Q NP_000836.2     418 NMHKDLCPG-YIGLCPRMS--TIDGKELLGYIRA-VNFNGSAGTPVTFNENGDA-PGRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       418 ~~~~~~~~~-~~~~~~~~~--~~~~~~l~~~l~~-~~f~G~~G~~v~Fd~~G~~-~~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      +.....+.. ....|....  ...+..+.+.+++ ..|.|.+| .+.||++|++ ...+.+++++    .+.++.+|.|+
T Consensus       293 ~~~~~~~~~~~~~~c~~~~~~~~~~~~l~~~l~~~~~~~g~~G-~i~fd~~g~~~~~~~~i~~~~----~~~~~~vg~~~  367 (390)
T 5EWM_A          293 ELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTG-RIEFNEDGDRKFAQYSIMNLQ----NRKLVQVGIFN  367 (390)
T ss_dssp             HHTTSSSCCCCCSSSTTCCSCCTTHHHHHHHHHTCCEEEETTE-EEEECTTSCEESCCEEEEEEE----TTEEEEEEEEC
T ss_pred             HHHhccCCCCCCCccCCCCchhccHHHHHHHHHcCCCCCCCcc-cEEECCCCCcccceEEEEEcC----CCeEEEEEEEe
Confidence            987543211 011222110  1134456667765 46888888 8999999998 4788888887    35789999998


Q NP_000836.2     493 NQLH-LKVEDMQWAHR  507 (908)
Q Consensus       493 ~~~~-~~~~~i~w~~~  507 (908)
                      .... .+...+.|+++
T Consensus       368 ~~~~~~~~~~~~w~~~  383 (390)
T 5EWM_A          368 GSYIIQNDRKIIWPGG  383 (390)
T ss_dssp             SSCEEECSSCCCCSSS
T ss_pred             CceeeecCCcccCCCC
Confidence            6522 22224678653


No 60
>3H6G_A Glutamate receptor, ionotropic kainate 2; MEMBRANE PROTEIN GLYCOPROTEIN, Cell junction; HET: TLA, NAG; 2.697A {Rattus norvegicus}
Probab=99.57  E-value=1.2e-19  Score=196.12  Aligned_cols=373  Identities=17%  Similarity=0.207  Sum_probs=225.6  Template_Neff=12.000

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCS-RDTYALEQSLTFVQ  121 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~-~~~~a~~~~~~~~~  121 (908)
                      .++++||+++|.++..            .+.....|+++|++++|+++++++++++++...|+.. +...+    .+.+.
T Consensus         2 ~~~i~ig~~~~~~g~~------------~~~~~~~~~~~a~~~~n~~~~~~~~~~l~~~~~d~~~~~~~~~----~~~~~   65 (395)
T 3H6G_A            2 THVLRFGGIFEYVESG------------PMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEA----SKKAC   65 (395)
T ss_dssp             CEEEEEEEEEEESSSC------------SCCHHHHHHHHHHHHHHHCSSSSSSEEEEEEEEEEETTCHHHH----HHHHH
T ss_pred             CCeEEEEEEeccCCCC------------CCcHHHHHHHHHHHHHhcCcccCCCCEEEEEEEecCcchhHHH----HHHHH
Confidence            4679999999998742            3567889999999999998877767888887777654 32211    11111


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +..                   .++++++||+.++.....++.++...++|+|++.+..+.+..  .+++++++.++...
T Consensus        66 ~~~-------------------~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~~  124 (395)
T 3H6G_A           66 DQL-------------------SLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDN--KDSFYVSLYPDFSS  124 (395)
T ss_dssp             HHH-------------------HHCCSCEECCSSHHHHHHHHHHHHHTTCCEEECSCCCCCTTC--CCCSEEEEEECHHH
T ss_pred             HHH-------------------hcCceEEECCCCHHHHHHHHHHHHHhCCCEEEeecCccccCC--CCceeEEcCCCHHH
Confidence            111                   147889999988877777888888999999998775544332  35788999999888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++++++++++++|+++++++.+ .++....+.+.+.+++. ++++... .+.  ....++...+++++. .+++++++.
T Consensus       125 ~~~~~~~~~~~~~~~~v~il~~~-~~~~~~~~~~~~~~~~~-~~~v~~~-~~~--~~~~~~~~~~~~l~~-~~~~~iv~~  198 (395)
T 3H6G_A          125 LSRAILDLVQFFKWKTVTVVYDD-STGLIRLQELIKAPSRY-NLRLKIR-QLP--ADTKDAKPLLKEMKR-GKEFHVIFD  198 (395)
T ss_dssp             HHHHHHHHHHHTTCSEEEEEESS-THHHHHTHHHHTGGGTS-SCEEEEE-ECC--SSGGGGHHHHHHHHH-TTCCEEEEE
T ss_pred             HHHHHHHHHHHcCCCEEEEEEeC-CccHHHHHHHHHCcCcc-CceEEEE-ECC--CCCCCcHHHHHHHHh-CCCeEEEEE
Confidence            88999999888899999999954 37766677777776664 3554432 222  223355666777753 477888877


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ........+++++++.|+.. .+.|+........... .  .....+...        ..+..+ .    ...+....+.
T Consensus       199 ~~~~~~~~~l~~~~~~g~~~~~~~~~~~~~~~~~~~~-~--~~~~~~~~~--------~~~~~~-~----~~~~~~~~~~  262 (395)
T 3H6G_A          199 CSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDV-E--PYRYSGVNM--------TGFRIL-N----TENTQVSSII  262 (395)
T ss_dssp             SCHHHHHHHHHHHHHTTCCSTTCEEEECCTTGGGBCC-T--TTTTSCCEE--------EEEECS-C----TTSHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHcCCCcCCeEEEEeeCCcccCcc-h--hhccCCeee--------EEEEEe-c----CCCcchHHHH
Confidence            76677788899998888753 2345543211100000 0  000001000        000000 0    0001111222


Q NP_000836.2     361 EFWEENF-GCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM-STID  438 (908)
Q Consensus       361 ~~~~~~~-~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~-~~~~  438 (908)
                      +.|.+.+ .+..           .+...     .....+..++..+|||+++++++++++....+..  ..|... ...+
T Consensus       263 ~~~~~~~~~~~~-----------~~~~~-----~~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~--~~~~~~~~~~~  324 (395)
T 3H6G_A          263 EKWSMERLQAPP-----------KPDSG-----LLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSS--LQCNRHKPWRF  324 (395)
T ss_dssp             HHHHHC-----------------CCSSC-----BCTTCCCHHHHHHHHHHHHHHHHHHTCTTCCCCC--CCTTSCCCCTT
T ss_pred             HHHHHHhhcCCC-----------CCCCC-----ccCcCCChHHHHHHHHHHHHHHHHHhccccCCCC--CCCCCCCCccc
Confidence            2222211 1100           00000     0001134567889999999999999986543211  112111 1123


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                      +..+.+.|++..|.|.+| ++.||++|++...+.+..++..  ++.++.||.|....
T Consensus       325 ~~~l~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~~~~~~~--~~~~~~vg~~~~~~  378 (395)
T 3H6G_A          325 GTRFMSLIKEAHWEGLTG-RITFNKTNGLRTDFDLDVISLK--EEGLEKIGTWDPAS  378 (395)
T ss_dssp             HHHHHHHHHHCEEEETTE-EEECCTTTSEECCCCEEEEEEE--TTEEEEEEEEETTT
T ss_pred             cHHHHHHHHhccccCCcc-eEEEcCCCCcccceEEEEEEee--ccccEEEEEEeCCC
Confidence            456777888888999988 8999987666554444333321  35789999998764


No 61
>3H6G_B Glutamate receptor, ionotropic kainate 2; MEMBRANE PROTEIN GLYCOPROTEIN, Cell junction; HET: NAG, TLA; 2.697A {Rattus norvegicus}
Probab=99.57  E-value=1.2e-19  Score=196.12  Aligned_cols=373  Identities=17%  Similarity=0.207  Sum_probs=226.1  Template_Neff=12.000

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCS-RDTYALEQSLTFVQ  121 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~-~~~~a~~~~~~~~~  121 (908)
                      .++++||+++|.++..            .+.....|+++|++++|+++++++++++++...|+.. +...+    .+.+.
T Consensus         2 ~~~i~ig~~~~~~g~~------------~~~~~~~~~~~a~~~~n~~~~~~~~~~l~~~~~d~~~~~~~~~----~~~~~   65 (395)
T 3H6G_B            2 THVLRFGGIFEYVESG------------PMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEA----SKKAC   65 (395)
T ss_dssp             CEEEEEEEEEEESSSC------------SCCHHHHHHHHHHHHHHHCSSSSSSEEEEEEEEEEETTCHHHH----HHHHH
T ss_pred             CCeEEEEEEeccCCCC------------CCcHHHHHHHHHHHHHhcCcccCCCCEEEEEEEecCcchhHHH----HHHHH
Confidence            4679999999998742            3567889999999999998877767888887777654 32211    11111


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +..                   .++++++||+.++.....++.++...++|+|++.+..+.+..  .+++++++.++...
T Consensus        66 ~~~-------------------~~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~~  124 (395)
T 3H6G_B           66 DQL-------------------SLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDN--KDSFYVSLYPDFSS  124 (395)
T ss_dssp             HHH-------------------HHCCSCEECCSSHHHHHHHHHHHHHTTCCEEECSCCCCCTTC--CCCSEEEEEECHHH
T ss_pred             HHH-------------------hcCceEEECCCCHHHHHHHHHHHHHhCCCEEEeecCccccCC--CCceeEEcCCCHHH
Confidence            111                   147889999988877777888888999999998775544332  35788999999888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++++++++++++|+++++++.+ .++....+.+.+.+++. ++++... .+.  ....++...+++++. .+++++++.
T Consensus       125 ~~~~~~~~~~~~~~~~v~il~~~-~~~~~~~~~~~~~~~~~-~~~v~~~-~~~--~~~~~~~~~~~~l~~-~~~~~iv~~  198 (395)
T 3H6G_B          125 LSRAILDLVQFFKWKTVTVVYDD-STGLIRLQELIKAPSRY-NLRLKIR-QLP--ADTKDAKPLLKEMKR-GKEFHVIFD  198 (395)
T ss_dssp             HHHHHHHHHHHTTCSEEEEEESS-THHHHHTHHHHTGGGTS-SCEEEEE-ECC--SSGGGCHHHHHHHHH-TTCCEEEEE
T ss_pred             HHHHHHHHHHHcCCCEEEEEEeC-CccHHHHHHHHHCcCcc-CceEEEE-ECC--CCCCCcHHHHHHHHh-CCCeEEEEE
Confidence            88999999888899999999954 37766677777776664 3554432 222  223355666777753 477888877


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ........+++++++.|+.. .+.|+........... .  .....+...        ..+..+ .    ...+....+.
T Consensus       199 ~~~~~~~~~l~~~~~~g~~~~~~~~~~~~~~~~~~~~-~--~~~~~~~~~--------~~~~~~-~----~~~~~~~~~~  262 (395)
T 3H6G_B          199 CSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDV-E--PYRYSGVNM--------TGFRIL-N----TENTQVSSII  262 (395)
T ss_dssp             SCHHHHHHHHHHHHHTTCCSTTCEEEECCTTGGGBCC-T--TTTTSCCEE--------EEEECS-C----TTSHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHcCCCcCCeEEEEeeCCcccCcc-h--hhccCCeee--------EEEEEe-c----CCCcchHHHH
Confidence            76677788899998888753 2345543211100000 0  000001000        000000 0    0001111222


Q NP_000836.2     361 EFWEENF-GCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM-STID  438 (908)
Q Consensus       361 ~~~~~~~-~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~-~~~~  438 (908)
                      +.|.+.+ .+..           .+...     .....+..++..+|||+++++++++++....+..  ..|... ...+
T Consensus       263 ~~~~~~~~~~~~-----------~~~~~-----~~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~--~~~~~~~~~~~  324 (395)
T 3H6G_B          263 EKWSMERLQAPP-----------KPDSG-----LLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSS--LQCNRHKPWRF  324 (395)
T ss_dssp             HHHHHHHTTSCC-----------CSSSC-----BCTTCCCHHHHHHHHHHHHHHHHHHTCTTCCCCC--CCTTSCCCCTT
T ss_pred             HHHHHHhhcCCC-----------CCCCC-----ccCcCCChHHHHHHHHHHHHHHHHHhccccCCCC--CCCCCCCCccc
Confidence            2222211 1100           00000     0001134567889999999999999986543211  112111 1123


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                      +..+.+.|++..|.|.+| ++.||++|++...+.+..++..  ++.++.||.|....
T Consensus       325 ~~~l~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~~~~~~~--~~~~~~vg~~~~~~  378 (395)
T 3H6G_B          325 GTRFMSLIKEAHWEGLTG-RITFNKTNGLRTDFDLDVISLK--EEGLEKIGTWDPAS  378 (395)
T ss_dssp             HHHHHHHHHTCEEEETTE-EEECCTTTSEECCCCEEEEEEE--TTEEEEEEEEETTT
T ss_pred             cHHHHHHHHhccccCCcc-eEEEcCCCCcccceEEEEEEee--ccccEEEEEEeCCC
Confidence            456777888888999988 8999987666554444333321  35789999998764


No 62
>6JFY_B Glutamate receptor ionotropic, kainate 3; Glutamate receptor, Kainate, SYM, MEMBRANE; 7.4A {Rattus norvegicus}
Probab=99.57  E-value=1.2e-19  Score=216.12  Aligned_cols=373  Identities=15%  Similarity=0.201  Sum_probs=239.8  Template_Neff=11.300

Q NP_000836.2      43 DGDIILGGLFPVHAK-GERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTFV  120 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~-~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~~  120 (908)
                      +++++||+++|.++. ..          ..+.....|+++|++++|+.+++++|+++++++.|++ +++..+    .+.+
T Consensus         2 ~~~i~ig~~~~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~~~~~~g~~l~l~~~d~~~~~~~~~----~~~~   67 (809)
T 6JFY_B            2 PHVIRIGGIFEYADGPNA----------QVMNAEEHAFRFSANIINRNRTLLPNTTLTYDIQRIHFHDSFEA----TKKA   67 (809)
T ss_pred             CCceEEEEEEeCCCCchh----------HHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEeCCCCCHHHH----HHHH
Confidence            468999999999864 21          3567889999999999999887777889999999977 453332    2233


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   +++++++|+.++..+.+++..++..++|++++.++++.+.+  ..++++++.|++.
T Consensus        68 ~~l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~  126 (809)
T 6JFY_B           68 CDQLA-------------------LGVVAIFGPSQGSTTNAVQSICNALEVPHIQLRWKHHPLDN--KDTFYVNLYPDYA  126 (809)
T ss_pred             HHHHH-------------------cCCCEEEcCCCcHHHHHHHHHHHHHCCCEEeCCCCCcccCC--CCCCeeecCCCHH
Confidence            33322                   47899999888877778888889999999998876665443  2577999999999


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      .+++++++++++++|+++++++ +++++....+.+++.+++. ++++.... +.  .+..++...++++++ .++|+|++
T Consensus       127 ~~~~~~~~~l~~~~~~~v~iv~-~~~~~~~~~~~~~~~~~~~-g~~v~~~~-~~--~~~~~~~~~~~~l~~-~~~~~vv~  200 (809)
T 6JFY_B          127 SLSHAILDLVQSLKWRSATVVY-DDSTGLIRLQELIMAPSRY-NIRLKIRQ-LP--IDSDDSRPLLKEMKR-GREFRIIF  200 (809)
T ss_pred             HHHHHHHHHHHHhCCCEEEEEE-eChhhHHHHHHHHHHHHHC-CCEEEeee-cC--CCCCCcHHHHHHHHH-hCCCEEEE
Confidence            9999999999888999999999 6778888888888888775 46665433 22  223456677777763 57899988


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      .+....+..++++++++|+.. .+.|+..+.+...... ........+......          + .    ...+....|
T Consensus       201 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~----------~-~----~~~~~~~~f  264 (809)
T 6JFY_B          201 DCSHTMAAQILKQAMAMGMMTEYYHFIFTTLDLYALDL-EPYRYSGVNLTGFRI----------L-N----VDNPHVSAI  264 (809)
T ss_pred             eCCHHHHHHHHHHHHHcCCCCCCeeEEEecCCCCCCch-HhhcCCceeEEEEec----------C-C----CCChHHHHH
Confidence            877777888999999888754 2456654432211100 000000011110000          0 0    001111122


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM-STID  438 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~-~~~~  438 (908)
                      .+.+++.+.....         ..|...      ....++.++..+|||++++++|++++....+..  ..|... ...+
T Consensus       265 ~~~~~~~~~~~~~---------~~~~~~------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~--~~~~~~~~~~~  327 (809)
T 6JFY_B          265 VEKWSMERLQAAP---------RAESGL------LDGVMMTDAALLYDAVHIVSVTYQRAPQMTVNS--LQCHRHKAWRF  327 (809)
T ss_pred             HHHHHHHHCCCCC---------CCCCCC------CCCCCCHHHHHHHHHHHHHHHHHHHhcCCCCCc--cccccCCCccc
Confidence            2222222110000         000000      001234567889999999999999987532111  111111 1124


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDA-P-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~-~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ++.+.++|++..|.|.+| ++.||++|++ . ..+.+.+++    ++.++.+|.|.+.
T Consensus       328 ~~~l~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~~i~~~~----~~~~~~v~~~~~~  380 (809)
T 6JFY_B          328 GGRFMNFIKEAQWEGLTG-RIVFNKTSGLRTDFDLDIISLK----EDGLEKVGVWSPA  380 (809)
T ss_pred             HHHHHHHHHhcCcCCCCC-cEEecCCCCccceeEEEEEecc----CCceEEeEEEeCC
Confidence            567788888889999988 8999986443 3 266777776    2568888988764


No 63
>5L2E_B Cerebellin-1; Synapse Protein, Cell Surface Protein; 4.152A {Rattus norvegicus}
Probab=99.57  E-value=1.3e-19  Score=211.78  Aligned_cols=379  Identities=16%  Similarity=0.219  Sum_probs=233.2  Template_Neff=11.900

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI-LDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~-~d~~~~~~~a~~~~~~~~  120 (908)
                      .+++++||+++|.++                .....|++.|++++|+++++++|+++++++ .|+++++..+.+.+    
T Consensus         2 ~~~~i~Ig~~~~~~~----------------~~~~~~~~~a~~~iN~~~~~~~g~~i~~~~~~d~~~~~~~a~~~~----   61 (688)
T 5L2E_B            2 SDSIIHIGAIFDESA----------------KKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQEA----   61 (688)
T ss_dssp             -CCCEEEEEEEETTC----------------HHHHHHHHHHHHHHHHCSSSSTTCCEEEEEEEECTTCHHHHHHHH----
T ss_pred             CCceeeeEEEecCCC----------------chhHHHHHHHHHHHhcCcccccCcceEEEEEEeCCCCHHHHHHHH----
Confidence            357899999999875                245689999999999988777789999998 88887754433333    


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAP-------ELSDNTRYDFFS  193 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~-------~l~~~~~~~~~~  193 (908)
                      .+++.                   ++++++||+.++..+..++.++...++|+|++.+..+       .+++...+++++
T Consensus        62 ~~l~~-------------------~~v~~viG~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~l~~~~~~~~~~  122 (688)
T 5L2E_B           62 CELMN-------------------QGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYT  122 (688)
T ss_dssp             HHHHH-------------------HCCSCEEEEECHHHHHHHHHHHHHHTCCEEEEECCGGGCCCCCCCCCCCTTSCCCE
T ss_pred             HHHHH-------------------cCeeEEEecCCcchHHHHHHHHHHcCCCEEEeecCCCCCCCCCcccccCCCCCceE
Confidence            33322                   4788999998887777788888999999999876554       333334578899


Q NP_000836.2     194 RVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE------PRPGEFEKIIK  267 (908)
Q Consensus       194 ~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~------~~~~~~~~~~~  267 (908)
                      ++.+++..++.++++++++++|+++++++++ +++....+.+.+.+++. ++++.....++..      ....+....++
T Consensus       123 ~~~~~~~~~~~~l~~~~~~~~~~~v~i~~~~-~~g~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~~~l~  200 (688)
T 5L2E_B          123 LSVRPPVYLNEVILRVVTEYAWQKFIIFYDS-EYDIRGIQEFLDKVSQQ-GMDVALQKVENNINKMITTLFDTMRIEELN  200 (688)
T ss_dssp             EECSCCCCHHHHHHHHHHHTTCCEEEEEECT-TCCGGGGHHHHHHHHHT-TCEEEEEECCSCHHHHHHHHHHHSCHHHHH
T ss_pred             EEecCChhHHHHHHHHHHHhCCcEEEEEEcC-ccchHHHHHHHHHHHhc-CcchHHHHhhchhHHhHHhhhccccHHHHH
Confidence            9999988889999999988899999988754 47777777888777765 4665443222110      00122334445


Q NP_000836.2     268 RLLETPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFR  346 (908)
Q Consensus       268 ~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~  346 (908)
                      ++.  ..+++|++......+..+++++++.|+.. ++.|+..+.+...............+........          .
T Consensus       201 ~~~--~~~~~ii~~~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------~  268 (688)
T 5L2E_B          201 RYR--DTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTF----------P  268 (688)
T ss_dssp             HHH--HHTTEEEEESCHHHHHHHHHHHHHTTSSCTTCEEEEECSCCCHHHHHHHHHHCCSEEEEEEECC----------C
T ss_pred             HHH--HhccEEEEEcCHHHHHHHHHHHHHccCcCCCeEEEEecCCcccCChHHHHhhccceEEEEEecC----------C
Confidence            443  25777777766667788999998888753 4567766543322110000001111111111000          0


Q NP_000836.2     347 SRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG  426 (908)
Q Consensus       347 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~  426 (908)
                         .........+.+.+++.+.              .|......    ...+..++..+|||++++++|++++....+..
T Consensus       269 ---~~~~~~~~~~~~~~~~~~~--------------~~~~~~~~----~~~~~~~~~~~ydav~~~~~al~~~~~~~~~~  327 (688)
T 5L2E_B          269 ---VPQNISQRCFRGNHRISST--------------LCDPKDPF----AQNMEISNLYIYDTVLLLANAFHKKLQDRKWH  327 (688)
T ss_dssp             ---CCCSSGGGSEETTEECCHH--------------HHCTTSHH----HHTCCHHHHHHHHHHHHHHHHHHHHHHTTCCC
T ss_pred             ---CCchhhhhccccCcccCCC--------------cCCCCCCc----cccccchHHHHHHHHHHHHHHHHHHHHcCCCC
Confidence               0000111112222222111              11000000    01234567789999999999999986543210


Q NP_000836.2     427 --YIGLCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDA-PGRYDIFQYQITN-KSTEYKVIGHWTNQL  495 (908)
Q Consensus       427 --~~~~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~-~~~~~i~~~~~~~-~~~~~~~Vg~~~~~~  495 (908)
                        ....|...   ...++..+.++|++.+|.|.+| .+.|+++|++ ...+.+++++... +...++.||.|....
T Consensus       328 ~~~~~~c~~~~~~~~~~~~~l~~~l~~~~~~g~~G-~v~f~~~g~~~~~~~~i~~~~~~~~~~~~~~~vg~~~~~~  402 (688)
T 5L2E_B          328 SMASLSCIRKNSKPWQGGRSMLETIKKGGVNGLTG-DLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPVT  402 (688)
T ss_dssp             CCCCCCSSSTTCCCCTTHHHHHHHHHTCEEECSSS-EEECCTTSBCCCCCEEEEEC--------CCEEEEEEETTT
T ss_pred             CCCCcccccCCCCCCccchHHHHHHHhCccccccc-eEEecCCCccceeEEEEEecCCCcccCCcEEEEEEEeCCC
Confidence              01122111   0114556778888889999988 8999999985 4678888887421 235789999998764


No 64
>3QEK_B NMDA glutamate receptor subunit; amino terminal domain, ion channel; HET: MSE, NAG, BMA; 2.001A {Xenopus laevis}
Probab=99.57  E-value=1.3e-19  Score=195.07  Aligned_cols=349  Identities=18%  Similarity=0.255  Sum_probs=220.0  Template_Neff=11.900

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.+                  ....|+++|++++|+.+ .++++++++...|+..++..+    .+.+.+
T Consensus         3 ~~~i~Ig~~~~~~------------------~~~~~~~~a~~~~n~~~-~~~~~~l~~~~~~~~~~~~~~----~~~~~~   59 (384)
T 3QEK_B            3 PKIVNIGAVLSTK------------------KHEQIFREAVNQANKRH-FTRKIQLQATSVTHRPNAIQM----ALSVCE   59 (384)
T ss_dssp             CCEEEEEEEESSH------------------HHHHHHHHHHHHHHHHC-----CEEEEEEEECCSSHHHH----HHHCCC
T ss_pred             CcceEEEEEechH------------------HHHHHHHHHHHHHhHhh-cCCCeeEEEEEecCCcCHHHH----HHHHHH
Confidence            4689999999875                  24578999999999864 345777777665544443222    222222


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAA-----ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-----~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      ++.                  .+++++++|+.     ++..+..++.++...++|+|++.+..+.+.+...+++++++.|
T Consensus        60 ~~~------------------~~~v~~vig~~~~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~  121 (384)
T 3QEK_B           60 DLI------------------SSQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP  121 (384)
T ss_dssp             CCG------------------GGTEEEEEECCC-------CCHHHHHHHHTTTCCEEESSCCCGGGGCSSSCTTEEESSC
T ss_pred             HHH------------------hcCcEEEEECCCCCCCCcCChHHHHHHHHhhCCCEEEccCCCccccCccccceEeecCC
Confidence            221                  15788999953     3344456677888899999998877666554335688999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQS-------QKIP------------REPR  258 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~-------~~~~------------~~~~  258 (908)
                      +....+.++++++.+++|+++++++.++.++....+.+++.+++. ++++...       ..+.            ....
T Consensus       122 ~~~~~~~~~~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  200 (384)
T 3QEK_B          122 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEGK-ESKSKKRNYENLDQLSYDNKRGPKADKVLQFEPG  200 (384)
T ss_dssp             CGGGGHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHH-HHHHHHHTC-------------CEEEEEEEECTT
T ss_pred             CHHHHHHHHHHHHHHcCCcEEEEEEecCcchhHHHHHHHHHHhcC-CCccccccccccccccccCCCCCCccceeecCCC
Confidence            998889999999988899999999987778887778888777765 3442110       0000            0011


Q NP_000836.2     259 PGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRAS  337 (908)
Q Consensus       259 ~~~~~~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~  337 (908)
                      ..++...+++++. .++|+|++.........+++++++.|+.+ ++.|+..+.+.....    ......+.         
T Consensus       201 ~~~~~~~~~~i~~-~~~~~ii~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~----~~~~~~~~---------  266 (384)
T 3QEK_B          201 TKNLTALLLEAKE-LEARVIILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGSA----LRYAPDGI---------  266 (384)
T ss_dssp             CCCCHHHHHHHHT-SSCCEEEEECCHHHHHHHHHHHHHTTCSSTTCEEEECSGGGSHHH----HHHCCTTC---------
T ss_pred             chhHHHHHHHHHh-CCCeEEEEECCHHHHHHHHHHHHHcCCCCCCEEEEEeccccCCch----hhcCCCcE---------
Confidence            2345566777763 57899888877777788889888887753 456665543221100    00000000         


Q NP_000836.2     338 IDGFDRYFRSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALH  417 (908)
Q Consensus       338 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~  417 (908)
                                                   +...                        ...+..++..+|||+++++++++
T Consensus       267 -----------------------------~~~~------------------------~~~~~~~~~~~ydav~~~~~al~  293 (384)
T 3QEK_B          267 -----------------------------IGLQ------------------------LINGKNESAHISDAVAVVAQAIH  293 (384)
T ss_dssp             -----------------------------EEEE------------------------ETTTTCHHHHHHHHHHHHHHHHH
T ss_pred             -----------------------------EEEE------------------------ecCCCcchhHHHHHHHHHHHHHH
Confidence                                         0000                        00112356789999999999999


Q NP_000836.2     418 NMHKDLCPG-YIGLCPRM--STIDGKELLGYIRA-VNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       418 ~~~~~~~~~-~~~~~~~~--~~~~~~~l~~~l~~-~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      ++....+.. ....|...  ....+..+.+.|++ ..|.|.+| ++.||++|++. ..+.+++++    ++.++.+|.|+
T Consensus       294 ~~~~~~~~~~~~~~c~~~~~~~~~~~~l~~~l~~~~~~~g~~G-~i~fd~~g~~~~~~~~i~~~~----~~~~~~vg~~~  368 (384)
T 3QEK_B          294 ELFEMENITDPPRGCVGNTNIWKTGPLFKRVLMSSKYPDGVTG-RIEFNEDGDRKFAQYSIMNLQ----NRKLVQVGIFN  368 (384)
T ss_dssp             HHTTSSCCCCCCSCCTTCCCCCTTHHHHHHHHHTCCEEEETTE-EECBCTTSCBCSCCEEEEEEE----TTEEEEEEEEC
T ss_pred             HHHhcCCCCCCCCCcCCCcchhccHHHHHHHHhcCCCCCCCCC-CEEECCCCCcCceEEEEEEcc----CCeEEEEEEEe
Confidence            986532110 01122111  11234556677765 56889888 89999999986 688888887    35799999998


Q NP_000836.2     493 NQL-HLKVEDMQWA  505 (908)
Q Consensus       493 ~~~-~~~~~~i~w~  505 (908)
                      ... .++...+.|+
T Consensus       369 ~~~~~~~~~~~~w~  382 (384)
T 3QEK_B          369 GSYIIQNDRKIIWP  382 (384)
T ss_dssp             SSSEEECSSCCCCT
T ss_pred             CCccccCCCcccCC
Confidence            652 2233457774


No 65
>6LU9_D Glutamate receptor ionotropic, delta-2; Membrane protein;{Rattus norvegicus}
Probab=99.57  E-value=1.3e-19  Score=217.96  Aligned_cols=374  Identities=16%  Similarity=0.230  Sum_probs=233.0  Template_Neff=11.400

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI-LDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~-~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ++++||+++|.++                .....|+++|++++|+++++++|+++++.+ .|+++++..+.+.    +.+
T Consensus         2 ~~i~IG~~~p~~g----------------~~~~~~~~~Ai~~in~~~~~~~g~~i~~~~~~d~~~~~~~~~~~----~~~   61 (877)
T 6LU9_D            2 SIIHIGAIFDESA----------------KKDDEVFRTAVGDLNQNEEILQTEKITFSVTFVDGNNPFQAVQE----ACE   61 (877)
T ss_dssp             CSSEEEEEECTTT----------------HHHHHHHHHHHHHHHTCCSSCSSCCCEEEEEECCTTCHHHHHHH----HHH
T ss_pred             CeEEEEEEeccCc----------------cchHHHHHHHHHHHHccccccccccceeEEEEcCCCCHHHHHHH----HHH
Confidence            5789999999864                246789999999999988777789999988 8887765443333    333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAP-------ELSDNTRYDFFSRV  195 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~-------~l~~~~~~~~~~~~  195 (908)
                      ++.                   +++++++|+.++..+..++..+...++|++++.++.+       .+++...++++++.
T Consensus        62 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~l~~~~~~~~~~~~  122 (877)
T 6LU9_D           62 LMN-------------------QGILALVSSIGCTSAGSLQSLADAMHIPHLFIQRSTAGTPRSGCGLTRSNRNDDYTLS  122 (877)
T ss_dssp             HHH-------------------HCCSCEEEEECHHHHHHHHHHHHHHTCCEEEEECCGGGCCCCCCSCCSCTTSCCCEEE
T ss_pred             HHH-------------------cCeeEEEecCChhhHHHHHHHHHHcCCCEEEeecCCCCCCCCCCCcccCCCCCCeEEE
Confidence            332                   5789999998887777888889999999999877655       34333456788888


Q NP_000836.2     196 VPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEF--------EKIIK  267 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~--------~~~~~  267 (908)
                      .+++..+++++++++++++|+++++++ +++++....+.+.+.+++. ++++.....++.  +..++        ...++
T Consensus       123 ~~~~~~~~~~l~~~l~~~~~~~v~il~-~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~--~~~~~~~~~~~~~~~~l~  198 (877)
T 6LU9_D          123 VRPPVYLNEVILRVVTEYAWQKFIIFY-DSEYDIRGIQEFLDKVSQQ-GMDVALQKVENN--INKMITTLFDTMRIEELN  198 (877)
T ss_dssp             CSCCCCHHHHHHHHHHHTTCSEEEEEE-CTTSCGGGSHHHHHHHHHT-TCEEEEEECCSS--HHHHHHHHHHHSCHHHHH
T ss_pred             ecCChhHHHHHHHHHHHhCCcEEEEEE-cCcccHHHHHHHHHHHHhc-CCceeEeecccc--hhHhHHHHHhhhcHHHHH
Confidence            888777888999998888999999999 7778877778888877765 355543322221  11111        12233


Q NP_000836.2     268 RLLETPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFR  346 (908)
Q Consensus       268 ~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~  346 (908)
                      ++.  .++|+|++......+..+++++++.|+.. .+.|+..+.+...............+........          .
T Consensus       199 ~~~--~~~~~ii~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------~  266 (877)
T 6LU9_D          199 RYR--DTLRRAILVMNPATAKSFISEVVETNLVAFDCHWIIINEEINDVDVQELVRRSIGRLTIIRQTF----------P  266 (877)
T ss_dssp             HHH--HHTTEEEEESCHHHHHHHHHHHHHTTSSCSSCEEEEECSCCCHHHHHHHHHHCSSEEEEEEEEC----------C
T ss_pred             HhH--HhCCeEEEEcCHHHHHHHHHHHHHcCCccCceEEEEEeCCcccccHHHHhhhhcccEEEEEecc----------C
Confidence            332  36788887777777888999999888753 4567766543321110000000111111110000          0


Q NP_000836.2     347 SRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG  426 (908)
Q Consensus       347 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~  426 (908)
                         .........+.+.+++.+.              .|...+..    ...+..++..+|||++++++|++++....+..
T Consensus       267 ---~~~~~~~~~f~~~~~~~~~--------------~~~~~~~~----~~~~~~~~~~~ydav~~~~~al~~~~~~~~~~  325 (877)
T 6LU9_D          267 ---VPQNISQRCFRGNHRISST--------------LCDPKDPF----AQNMEISNLYIYDTVLLLANAFHKKLQDRKWH  325 (877)
T ss_dssp             ---CCSSHHHHHEETTEECCTT--------------TSCTTSHH----HHTCCHHHHHHHHHHHHHHHHHHHHHHTTCCC
T ss_pred             ---CCcccccccccccccccCC--------------cCCCCCCc----ccccchhHHHHHHHHHHHHHHHHHHHHcCCcc
Confidence               0000011112222221111              01000000    01234567889999999999999886532110


Q NP_000836.2     427 --YIGLCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDA-PGRYDIFQYQITN-KSTEYKVIGHWTNQ  494 (908)
Q Consensus       427 --~~~~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~-~~~~~i~~~~~~~-~~~~~~~Vg~~~~~  494 (908)
                        ....|...   ...++..+.+++++..|.|.+| .+.||++|++ ...+.+++++..+ ..+.+..||.|...
T Consensus       326 ~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~~~~~~~~~~~~v~~~~~~  399 (877)
T 6LU9_D          326 SMASLSCIRKNSKPWQGGRSMLETIKKGGVNGLTG-DLEFGENGGNPNVHFEILGTNYGEELGRGVRKLGCWNPV  399 (877)
T ss_dssp             CCCCCCSSSTTCCCCHHHHHHHHHHHTCEEECSSS-EEECCTTSBCCCCEEEEEEEEEEETTEEEEEEEEEEETT
T ss_pred             ccccccccCCCCCccccchHHHHHHHhcccCceee-eEEcCCCCCcccEEEEEEecccccccCCcEEEEEEEeCC
Confidence              00112110   1124566888888889999998 8999999998 4688888887421 12468888988754


No 66
>1USG_A LEUCINE-SPECIFIC BINDING PROTEIN; LEUCINE-BINDING PROTEIN, PROTEIN STRUCTURE, ABC; 1.53A {ESCHERICHIA COLI} SCOP: c.93.1.1
Probab=99.56  E-value=2.1e-19  Score=190.09  Aligned_cols=335  Identities=20%  Similarity=0.239  Sum_probs=214.3  Template_Neff=12.300

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ++++||+++|.++...          ..+.....+++.|++++|+.+++. |+++++.+.|+.+++..    ..+.++++
T Consensus         1 ~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~~~~~~~-g~~i~~~~~~~~~~~~~----~~~~~~~l   65 (346)
T 1USG_A            1 DDIKVAVVGAMSGPIA----------QWGDMEFNGARQAIKDINAKGGIK-GDKLVGVEYDDACDPKQ----AVAVANKI   65 (346)
T ss_dssp             CCEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHHHHTTTBT-TBCEEEEEEECTTCHHH----HHHHHHHH
T ss_pred             CCeEEEEEecCCCCch----------hhhHHHHHHHHHHHHHHHHCCCCC-CceEEEEEEcCCCCHHH----HHHHHHHH
Confidence            3689999999775321          255678899999999999876543 67788888776655332    23334433


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      +.                   ++++++|++.++.....+...+...++|+|.+....+.+... .+++++++.+++...+
T Consensus        66 ~~-------------------~~v~~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~~-~~~~~~~~~~~~~~~~  125 (346)
T 1USG_A           66 VN-------------------DGIKYVIGHLCSSSTQPASDIYEDEGILMISPGATNPELTQR-GYQHIMRTAGLDSSQG  125 (346)
T ss_dssp             HH-------------------TTCCEEECCSSHHHHHHHHHHHHHHTCEEEECCCCCGGGGSS-CCSSEEECSCCGGGHH
T ss_pred             Hh-------------------CCCCEEEcCCCchhhHHHHHHHHHhCCEEEecCCCCHHHHhc-CCCceEEecCChhhhH
Confidence            32                   478889988776665566677788899999987665544322 3567888888888888


Q NP_000836.2     204 QAMVDIV-TALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       204 ~~~~~~l-~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      +.+++++ ++.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++|++++..
T Consensus       126 ~~~~~~l~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i~~~~  201 (346)
T 1USG_A          126 PTAAKYILETVKPQRIAIIHDKQQYGEGLARSVQDGLKAA-NANVVFFDGIT--AGEKDFSALIARLKK-ENIDFVYYGG  201 (346)
T ss_dssp             HHHHHHCCCCCCCSSEEEEECSSHHHHHHHHHHHHHHHHT-TCCEEEEEECC--TTCCCCHHHHHHHHH-TTCCEEEEES
T ss_pred             HHHHHHHHHhhCCCEEEEEEcCCccchhHHHHHHHHHHHC-CCeEeEEeccC--CCCCChHHHHHHHHH-CCCCEEEEec
Confidence            8889887 45689999999976667778888888888775 35554322222  122345556666653 5788888776


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEF  362 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  362 (908)
                      .+..+..+++++++.|+  ++.|++.+.+...... ........+.+...+..              +...+....|.+.
T Consensus       202 ~~~~~~~~~~~~~~~g~--~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~--------------~~~~~~~~~f~~~  264 (346)
T 1USG_A          202 YYPEMGQMLRQARSVGL--KTQFMGPEGVGNASLS-NIAGDAAEGMLVTMPKR--------------YDQDPANQGIVDA  264 (346)
T ss_dssp             CHHHHHHHHHHHHHTTC--CCEEEECGGGCCTTHH-HHHGGGGTTCEEEECCC--------------GGGSGGGHHHHHH
T ss_pred             ChHHHHHHHHHHHHcCC--CCeEEcCcccccHHHH-HHHchhhcCcEEEcCCC--------------cCCChhHHHHHHH
Confidence            55567788888888877  3567766543322110 00011122222111100              0001111222222


Q NP_000836.2     363 WEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKEL  442 (908)
Q Consensus       363 ~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~l  442 (908)
                      +++.+.                           ..+..++..+|||++++++++++....               +++.+
T Consensus       265 ~~~~~~---------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~---------------~~~~i  302 (346)
T 1USG_A          265 LKADKK---------------------------DPSGPYVWITYAAVQSLATALERTGSD---------------EPLAL  302 (346)
T ss_dssp             HHHTTC---------------------------CCCCHHHHHHHHHHHHHHHHHHHHCCC---------------CHHHH
T ss_pred             HHHhhC---------------------------CCCCHHHHHHHHHHHHHHHHHHHhCCC---------------CHHHH
Confidence            222111                           112345778999999999999886531               34467


Q NP_000836.2     443 LGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQ  477 (908)
Q Consensus       443 ~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~  477 (908)
                      .+.|++..|.|.+| ++.||++|++. ..+.+++++
T Consensus       303 ~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~  337 (346)
T 1USG_A          303 VKDLKANGANTVIG-PLNWDEKGDLKGFDFGVFQWH  337 (346)
T ss_dssp             HHHHHHHCEEETTE-EECBCTTSSBSSCCCEEEEEC
T ss_pred             HHHHHhCCCCccCc-ceeeCCCCCcCcccEEEEEEe
Confidence            78888888999999 89999988876 467777776


No 67
>3IP6_A ABC transporter, substrate binding protein; VENUS FLYTRAP DOMAIN, TRANSPORT PROTEIN; 1.4A {Agrobacterium tumefaciens}
Probab=99.55  E-value=2.6e-19  Score=190.40  Aligned_cols=349  Identities=15%  Similarity=0.188  Sum_probs=218.3  Template_Neff=12.000

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ++++||+++|.++..          ...+.....+++.|++++|+.+++. |+++++.+.|+..++.    ...+.++++
T Consensus         1 ~~~~Ig~i~~~~~~~----------~~~~~~~~~g~~~a~~~~n~~~~~~-g~~i~~~~~~~~~~~~----~~~~~~~~l   65 (356)
T 3IP6_A            1 MDVVIAVGAPLTGPN----------AAFGAQIQKGAEQAAKDINAAGGIN-GEQIKIVLGDDVSDPK----QGISVANKF   65 (356)
T ss_dssp             CCEEEEEEECSSSTT----------HHHHHHHHHHHHHHHHHHHHTTCBT-TBCEEEEEEECTTCHH----HHHHHHHHH
T ss_pred             CcEEEEEEecCCCCC----------hHHHHHHHHHHHHHHHHHHHcCCcC-CceeEEEEecCCCCHH----HHHHHHHHH
Confidence            368999999976532          1256678899999999999876543 6778887777655433    223334443


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      +.                   ++++++|++.++.....+...+...++|+|.+....+.+... ..++++++.++....+
T Consensus        66 ~~-------------------~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~~~~~  125 (356)
T 3IP6_A           66 VA-------------------DGVKFVVGHFNSGVSIPASEVYAENGILEITPAATNPVFTER-GLWNTFRTCGRDDQQG  125 (356)
T ss_dssp             HH-------------------TTCCEEEECSSHHHHHHHHHHHHTTTCEEEESSCCCGGGGSS-CCTTEEESSCCHHHHH
T ss_pred             HH-------------------CCCCEEEecCCchhhHHHHHHHHHcCCEEEccCCCChhhhcc-CCcCeEEecCChhHHH
Confidence            32                   478889987766655566677788899999988765543322 2356788888888888


Q NP_000836.2     204 QAMVDIV-TALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       204 ~~~~~~l-~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      +.+++++ ++++|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....++++++ .+++++++..
T Consensus       126 ~~~~~~l~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i~~~~  201 (356)
T 3IP6_A          126 GIAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAANAA-GVTEVMYEGVN--VGDKDFSALISKMKE-AGVSIIYWGG  201 (356)
T ss_dssp             HHHHHHHHHHCTTCCEEEEECSSHHHHHHHHHHHHHHHHT-TCCCSEEEECC--TTCCCCHHHHHHHHH-TTCCEEEEES
T ss_pred             HHHHHHHHHhcCCCeEEEEeCCChhhHHHHHHHHHHHHHC-CCeeeEeeccC--CCCCChHHHHHHHHH-hCCCEEEEeC
Confidence            8888888 45699999999976667777888888888775 35543322222  122344555666653 4778877776


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEF  362 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  362 (908)
                      .+..+..+++++++.|+.  ..|++.+.+...... ........+.+.....           .   +...+....|.+.
T Consensus       202 ~~~~~~~~~~~~~~~g~~--~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~---~~~~~~~~~f~~~  264 (356)
T 3IP6_A          202 LHTEAGLIIRQAADQGLK--AKLVSGDGIVSNELA-SIAGDAVEGTLNTFGP-----------D---PTLRPENKELVEK  264 (356)
T ss_dssp             CHHHHHHHHHHHHHHTCC--CEEEECTTCCSHHHH-HHHGGGGTTCEEEECC-----------C---GGGCGGGHHHHHH
T ss_pred             chHHHHHHHHHHHHCCCC--CeEEEcccccCHHHH-HHHhHHhcCceeecCC-----------C---cccChhHHHHHHH
Confidence            566778888988888774  356665543221110 0001112222211100           0   0001111222222


Q NP_000836.2     363 WEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKEL  442 (908)
Q Consensus       363 ~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~l  442 (908)
                      +++ +.                           ..+..++..+|||++++++++++...               .++..+
T Consensus       265 ~~~-~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~---------------~~~~~l  301 (356)
T 3IP6_A          265 FKA-AG---------------------------FNPEAYTLYSYAAMQAIAGAAKAAGS---------------VEPEKV  301 (356)
T ss_dssp             HHH-TT---------------------------CCCCTTHHHHHHHHHHHHHHHHHHTC---------------CCHHHH
T ss_pred             HHH-hC---------------------------CCCChHHHHHHHHHHHHHHHHHHcCC---------------CCHHHH
Confidence            221 10                           11234567899999999999987642               134567


Q NP_000836.2     443 LGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       443 ~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                      .+.|++..|.|.+| .+.||++|++. ..+.+.+++... ++.|+.++.|..
T Consensus       302 ~~~l~~~~~~g~~g-~i~f~~~g~~~~~~~~i~~~~~~~-~g~~~~~~~~~~  351 (356)
T 3IP6_A          302 AEALKKGSFPTALG-EISFDEKGDPKLPGYVMYEWKKGP-DGKFTYIQQGSH  351 (356)
T ss_dssp             HHHHTTCCBCCTTS-SBCBCTTSCBCCCCCEEEEEEECT-TSSEEEEEC---
T ss_pred             HHHHHcCCCCcCce-eEEECCCCCccCCeEEEEEEEeCC-CCcEEEEecCCC
Confidence            78888888999888 89999989875 467787876321 357888887753


No 68
>3IPC_A ABC transporter, substrate binding protein; VENUS FLYTRAP DOMAIN, TRANSPORT PROTEIN; 1.3A {Agrobacterium tumefaciens}
Probab=99.55  E-value=2.7e-19  Score=190.15  Aligned_cols=348  Identities=16%  Similarity=0.198  Sum_probs=218.0  Template_Neff=12.100

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||+++|.++..          ...+.....+++.|++++|+.+++. |+++++.+.|+..++.    ...+.+++++
T Consensus         2 ~~~Ig~~~~~~~~~----------~~~~~~~~~~~~~a~~~~n~~~~~~-g~~i~~~~~~~~~~~~----~~~~~~~~l~   66 (356)
T 3IPC_A            2 DVVIAVGAPLTGPN----------AAFGAQIQKGAEQAAKDINAAGGIN-GEQIKIVLGDDVSDPK----QGISVANKFV   66 (356)
T ss_dssp             CEEEEEEECCSSTT----------HHHHHHHHHHHHHHHHHHHHTTCBT-TBCEEEEEEECTTCHH----HHHHHHHHHH
T ss_pred             CeEEEEEeCCCCCc----------hHHHHHHHHHHHHHHHHHHHCCCcC-CceeEEEEecCCCCHH----HHHHHHHHHH
Confidence            67899999977532          1356778899999999999876543 6778887777655533    2233344333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   ++++++|++.++.....+...+...++|+|.+.+..+.+... ..++++++.++....++
T Consensus        67 ~-------------------~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~  126 (356)
T 3IPC_A           67 A-------------------DGVKFVVGHANSGVSIPASEVYAENGILEITPAATNPVFTER-GLWNTFRTCGRDDQQGG  126 (356)
T ss_dssp             H-------------------TTCCEEEECSSHHHHHHHHHHHHTTTCEEEESSCCCGGGGSS-CCTTEEESSCCHHHHHH
T ss_pred             h-------------------CCCCEEEccCCchhhHHHHHHHHHcCCEEEecCCCChhhhcc-CCCCeEEecCChhHHHH
Confidence            2                   478899988766655566677788899999987655543321 24567888888888888


Q NP_000836.2     205 AMVDIV-TALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFAN  283 (908)
Q Consensus       205 ~~~~~l-~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~~  283 (908)
                      .+++++ ++++|++|++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .+++++++...
T Consensus       127 ~~~~~l~~~~~~~~v~~l~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~~~~  202 (356)
T 3IPC_A          127 IAGKYLADHFKDAKVAIIHDKTPYGQGLADETKKAANAA-GVTEVMYEGVN--VGDKDFSALISKMKE-AGVSIIYWGGL  202 (356)
T ss_dssp             HHHHHHHHHCTTCCEEEEECSSHHHHHHHHHHHHHHHHT-TCCCSEEEECC--TTCCCCHHHHHHHHH-TTCCEEEEESC
T ss_pred             HHHHHHHHhcCCCEEEEEECCChhhHhHHHHHHHHHHHC-CCeEeEEEccC--CCCcCHHHHHHHHHH-cCCCEEEEeCc
Confidence            888887 45699999999966667777888888887765 35544322222  122344556666653 47888777765


Q NP_000836.2     284 EDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFW  363 (908)
Q Consensus       284 ~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  363 (908)
                      +..+..+++++++.|+.  ..|++.+.+...... ........+.+.....           .   +...+....|.+.+
T Consensus       203 ~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~---~~~~~~~~~f~~~~  265 (356)
T 3IPC_A          203 HTEAGLIIRQAADQGLK--AKLVSGDGIVSNELA-SIAGDAVEGTLNTFGP-----------D---PTLRPENKELVEKF  265 (356)
T ss_dssp             HHHHHHHHHHHHHHTCC--CEEEECGGGCSHHHH-HHHGGGGTTCEEEESC-----------C---GGGCGGGHHHHHHH
T ss_pred             hHHHHHHHHHHHHCCCC--CeEEechhhcCHHHH-HHhhHHhcCceeecCC-----------C---CCCChhHHHHHHHH
Confidence            66677889998888874  356665533221110 0001112222211100           0   00001111122222


Q NP_000836.2     364 EENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELL  443 (908)
Q Consensus       364 ~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~l~  443 (908)
                      ++. .                           ..+..++..+|||++++++++++...               .++..+.
T Consensus       266 ~~~-~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~---------------~~~~~l~  302 (356)
T 3IPC_A          266 KAA-G---------------------------FNPEAYTLYSYAAMQAIAGAAKAAGS---------------VEPEKVA  302 (356)
T ss_dssp             HHT-T---------------------------CCCCTTHHHHHHHHHHHHHHHHHHTC---------------CCHHHHH
T ss_pred             HHc-C---------------------------CCCchHHHHHHHHHHHHHHHHHHcCC---------------CCHHHHH
Confidence            110 0                           01234567899999999999987642               1345677


Q NP_000836.2     444 GYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       444 ~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                      ++|++..|.|.+| ++.||++|++. ..+.+.+++..+ ++.++.++.|+.
T Consensus       303 ~~l~~~~~~g~~G-~i~f~~~g~~~~~~~~i~~~~~~~-~g~~~~~~~~~~  351 (356)
T 3IPC_A          303 EALKKGSFPTALG-EISFDEKGDPKLPGYVMYEWKKGP-DGKFTYIQQGSH  351 (356)
T ss_dssp             HHHTTCCBCCTTS-SBCBCTTSCBCCCCCEEEEEEECT-TSSEEEEEC---
T ss_pred             HHHHcCCCCccce-EEEECCCCCccCCeEEEEEEEECC-CccEEEEecCCC
Confidence            8888888999888 89999989875 467787886321 357888887764


No 69
>4EYG_B Twin-arginine translocation pathway signal; PSI-BIOLOGY, MCSG, MIDWEST CENTER FOR; HET: VNL, MSE; 1.86A {Rhodopseudomonas palustris}
Probab=99.55  E-value=3.1e-19  Score=190.67  Aligned_cols=356  Identities=16%  Similarity=0.187  Sum_probs=222.9  Template_Neff=12.100

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|.++...          ..+.....+++.|++++|..   ..|+++++.+.|+.+++.    ...+.++
T Consensus         3 ~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~~~---~~g~~v~~~~~d~~~~~~----~~~~~~~   65 (368)
T 4EYG_B            3 AEDTFKVGLIVPMTGGQA----------STGKQIDNAIKLYIKKHGDT---VAGKKIEVILKDDAAIPD----NTKRLAQ   65 (368)
T ss_dssp             -CCEEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHHCSE---ETTEEEEEEEEECTTCHH----HHHHHHH
T ss_pred             CCCcEEEEEEEcCCCCCh----------HHHHHHHHHHHHHHHHhCCc---cCCEEEEEEEEcCCCCch----HHHHHHH
Confidence            457899999999876421          25567888999999998851   235677877777655533    2233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                  .++++++|++..+.....+...+...++|+|.+....+.+..  .+++++++.+++..
T Consensus        66 ~l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~~  125 (368)
T 4EYG_B           66 ELIV------------------NDKVNVIAGFGITPAALAAAPLATQAKVPEIVMAAGTSIITE--RSPYIVRTSFTLAQ  125 (368)
T ss_dssp             HHHH------------------TSCCSEEEECSSHHHHHHHHHHHHHHTCCEEESSCCCGGGGG--GCTTEEESSCCHHH
T ss_pred             HHHh------------------cCCcCEEEecCChHHHHHHHHHHHHcCCCEEEcCCCCccccC--CCCcEEEcCCChhh
Confidence            4332                  157889998876666566667778899999988765543322  24678888898888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++|++++.
T Consensus       126 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i~~~  201 (368)
T 4EYG_B          126 SSIIIGDWAAKNGIKKVATLTSDYAPGNDALAFFKERFTAG-GGEIVEEIKVP--LANPDFAPFLQRMKD-AKPDAMFVF  201 (368)
T ss_dssp             HHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--SSSCCCHHHHHHHHH-HCCSEEEEE
T ss_pred             hHHHHHHHHHHCCCCEEEEEecCChhhHHHHHHHHHHHHhC-CCeeceEEecC--CCCCCcHHHHHHHHH-hCCCEEEEE
Confidence            88899999877899999999966667777888888888765 35543322222  122344556666653 578888877


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      .....+..+++++++.|+.. ++.|++.+.+...... ........+.+......          .   ....+....|.
T Consensus       202 ~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~---~~~~~~~~~f~  267 (368)
T 4EYG_B          202 VPAGQGGNFMKQFAERGLDKSGIKVIGPGDVMDDDLL-NSMGDAALGVVTAHMYS----------A---AHPSAMNKEFV  267 (368)
T ss_dssp             CCTTCHHHHHHHHHHTTGGGTTCEEEEEGGGGCTTTG-GGCCGGGTTCEEEESCC----------T---TCCCHHHHHHH
T ss_pred             eccchHHHHHHHHHHcCCCcCCCEEEccccccCHHHH-HHchhhhCCcEEEeccc----------C---CCCCHHHHHHH
Confidence            65466778888888888753 3566665533221110 00111122222211100          0   00001111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++                           ..+..++..+|||++++++++++....              .+++
T Consensus       268 ~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~--------------~~~~  306 (368)
T 4EYG_B          268 AAYKKEFG---------------------------QRPGFMAVGGYDGIHLVFEALKKTGGK--------------ADGD  306 (368)
T ss_dssp             HHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHTTTC--------------CSHH
T ss_pred             HHHHHHHC---------------------------CCCChHHHHHHHHHHHHHHHHHHhCCC--------------CCHH
Confidence            22222111                           112345778999999999999886421              2345


Q NP_000836.2     441 ELLGYIRAVNFNGSAGTPVTFNEN-GDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       441 ~l~~~l~~~~f~G~~G~~v~Fd~~-G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .+.++|++.+|.|.+| ++.|+++ |++...+.+.+++..++...++.+|.|...
T Consensus       307 ~v~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~i~~~~~~~g~~~~~~vg~~~~~  360 (368)
T 4EYG_B          307 SLIAAMKGMKWESPRG-PISIDPETRDIVQNIYIRKVEKVDGELYNIEFAKFDAV  360 (368)
T ss_dssp             HHHHHHTTCEEEETTE-EEEECTTTCCEEEEEEEEEEEEETTEEEEEEEEEEEEE
T ss_pred             HHHHHHhCCCccCCCc-ceEeCCCCCcccceEEEEEEEeeCCeEEEeEEEEecCC
Confidence            6778888778999888 8999975 566667888888732223457888888754


No 70
>4EYK_A Twin-arginine translocation pathway signal; PSI-BIOLOGY, MCSG, MIDWEST CENTER FOR; HET: DHB; 1.9A {Rhodopseudomonas palustris}
Probab=99.55  E-value=3.1e-19  Score=190.67  Aligned_cols=356  Identities=16%  Similarity=0.187  Sum_probs=222.9  Template_Neff=12.100

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|.++...          ..+.....+++.|++++|..   ..|+++++.+.|+.+++.    ...+.++
T Consensus         3 ~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~~~---~~g~~v~~~~~d~~~~~~----~~~~~~~   65 (368)
T 4EYK_A            3 AEDTFKVGLIVPMTGGQA----------STGKQIDNAIKLYIKKHGDT---VAGKKIEVILKDDAAIPD----NTKRLAQ   65 (368)
T ss_dssp             -CCEEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHHCSE---ETTEEEEEEEEECTTCHH----HHHHHHH
T ss_pred             CCCcEEEEEEEcCCCCCh----------HHHHHHHHHHHHHHHHhCCc---cCCEEEEEEEEcCCCCch----HHHHHHH
Confidence            457899999999876421          25567888999999998851   235677877777655533    2233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                  .++++++|++..+.....+...+...++|+|.+....+.+..  .+++++++.+++..
T Consensus        66 ~l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~~  125 (368)
T 4EYK_A           66 ELIV------------------NDKVNVIAGFGITPAALAAAPLATQAKVPEIVMAAGTSIITE--RSPYIVRTSFTLAQ  125 (368)
T ss_dssp             CCCC------------------CSCCSEEEECCSHHHHHHHHHHHHHHTCCEEESSCCCGGGGG--GCTTEEESSCCHHH
T ss_pred             HHHh------------------cCCcCEEEecCChHHHHHHHHHHHHcCCCEEEcCCCCccccC--CCCcEEEcCCChhh
Confidence            4332                  157889998876666566667778899999988765543322  24678888898888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++|++++.
T Consensus       126 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i~~~  201 (368)
T 4EYK_A          126 SSIIIGDWAAKNGIKKVATLTSDYAPGNDALAFFKERFTAG-GGEIVEEIKVP--LANPDFAPFLQRMKD-AKPDAMFVF  201 (368)
T ss_dssp             HHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--SSSCCCHHHHHHHHH-HCCSEEEEE
T ss_pred             hHHHHHHHHHHCCCCEEEEEecCChhhHHHHHHHHHHHHhC-CCeeceEEecC--CCCCCcHHHHHHHHH-hCCCEEEEE
Confidence            88899999877899999999966667777888888888765 35543322222  122344556666653 578888877


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      .....+..+++++++.|+.. ++.|++.+.+...... ........+.+......          .   ....+....|.
T Consensus       202 ~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~---~~~~~~~~~f~  267 (368)
T 4EYK_A          202 VPAGQGGNFMKQFAERGLDKSGIKVIGPGDVMDDDLL-NSMGDAALGVVTAHMYS----------A---AHPSAMNKEFV  267 (368)
T ss_dssp             CCTTCHHHHHHHHHHTTGGGTTCEEEEEGGGGCHHHH-TTCCGGGTTCEEEESCC----------T---TCCCHHHHHHH
T ss_pred             eccchHHHHHHHHHHcCCCcCCCEEEccccccCHHHH-HHchhhhCCcEEEeccc----------C---CCCCHHHHHHH
Confidence            65466778888888888753 3566665533221110 00111122222211100          0   00001111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++                           ..+..++..+|||++++++++++....              .+++
T Consensus       268 ~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~--------------~~~~  306 (368)
T 4EYK_A          268 AAYKKEFG---------------------------QRPGFMAVGGYDGIHLVFEALKKTGGK--------------ADGD  306 (368)
T ss_dssp             HHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHTTTC--------------CSHH
T ss_pred             HHHHHHHC---------------------------CCCChHHHHHHHHHHHHHHHHHHhCCC--------------CCHH
Confidence            22222111                           112345778999999999999886421              2345


Q NP_000836.2     441 ELLGYIRAVNFNGSAGTPVTFNEN-GDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       441 ~l~~~l~~~~f~G~~G~~v~Fd~~-G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .+.++|++.+|.|.+| ++.|+++ |++...+.+.+++..++...++.+|.|...
T Consensus       307 ~v~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~i~~~~~~~g~~~~~~vg~~~~~  360 (368)
T 4EYK_A          307 SLIAAMKGMKWESPRG-PISIDPETRDIVQNIYIRKVEKVDGELYNIEFAKFDAV  360 (368)
T ss_dssp             HHHHHHTTCEEEETTE-EEEECTTTCCEEEEEEEEEEEEETTEEEEEEEEEEEEE
T ss_pred             HHHHHHhCCCccCCCc-ceEeCCCCCcccceEEEEEEEeeCCeEEEeEEEEecCC
Confidence            6778888778999888 8999975 566667888888732223457888888754


No 71
>3HUT_A putative branched-chain amino acid ABC; Extracellular ligand-binding receptor,Transport protein,Receptor or; 1.93A {Rhodospirillum rubrum ATCC 11170}
Probab=99.54  E-value=4e-19  Score=189.00  Aligned_cols=350  Identities=17%  Similarity=0.219  Sum_probs=215.6  Template_Neff=12.100

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||++.|.++..          ...+.....+++.|++++|+.+++ .|.++++...|+.+++..    ..+.+++
T Consensus         2 ~~~~~Ig~i~~~~~~~----------~~~~~~~~~~~~~a~~~~n~~~~~-~g~~v~~~~~d~~~~~~~----~~~~~~~   66 (358)
T 3HUT_A            2 SLALLLGYELPLTGAN----------AAYGRVFQEAARLQLDRFNAAGGV-GGRPVDILYADSRDDADQ----ARTIARA   66 (358)
T ss_dssp             -CCEEEEEEECSSSTT----------HHHHHHHHHHHHHHHHHHHHTTTB-TTBCEEEEEEECTTCHHH----HHHHHHH
T ss_pred             CcceEEEEEecCCCCc----------HHHHHHHHHHHHHHHHHHHHcCCC-CCeeeEEEEecCCCCHHH----HHHHHHH
Confidence            4678999999976532          124567889999999999987654 367788877776555332    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                  ..+++++|++.++.....+...+...++|+|.++...+.+.  ...++++++.++....
T Consensus        67 ~~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~--~~~~~~~~~~~~~~~~  126 (358)
T 3HUT_A           67 FVD------------------DPRVVGVLGDFSSTVSMAAGSIYGKEGMPQLSPTAAHPDYI--KISPWQFRAITTPAFE  126 (358)
T ss_dssp             HHH------------------CTTEEEEEECSSHHHHHHHHHHHHHHTCCEEESSCCCGGGT--TSCTTEEESSCCGGGH
T ss_pred             Hhh------------------CCCEEEEEcCCCcHHHHHHHHHHHHhCCCEEccCCCCcchh--ccCCCeeEecCCccch
Confidence            332                  14788899887766555666777888999998876554332  1246788999998888


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      ++.+++++.+.+|++|++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .+++++++..
T Consensus       127 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~~~  202 (358)
T 3HUT_A          127 GPNNAAWMIGDGFTSVAVIGVTTDWGLSSAQAFRKAFELR-GGAVVVNEEVP--PGNRRFDDVIDEIED-EAPQAIYLAM  202 (358)
T ss_dssp             HHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCCCCHHHHHHHHH-HCCSEEEEES
T ss_pred             HHHHHHHHHhCCCCEEEEEEeCChhhHHHHHHHHHHHHHc-CCeEeeEEEeC--CCCCCHHHHHHHHHh-hCCCEEEEeC
Confidence            8899999887899999999976667778888888888775 35543322222  122345556666653 4788887776


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEF  362 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  362 (908)
                      .+..+..+++++++.|+.  ..+++.+.+...... ........+.+......          .   ....+....|.+.
T Consensus       203 ~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~---~~~~~~~~~f~~~  266 (358)
T 3HUT_A          203 AYEDAAPFLRALRARGSA--LPVYGSSALYSPKFI-DLGGPAVEGVRLATAFV----------L---GASDPVVVEFVSA  266 (358)
T ss_dssp             CHHHHHHHHHHHHHTTCC--CCEEECGGGCSHHHH-HHHGGGGTTCEEEESCC----------T---TCCSHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHCCCC--CCEEecchhcCHHHH-HhhcHHhCCeEEEEccc----------C---CCCCHHHHHHHHH
Confidence            566677888888887773  345554433221110 00011122222111000          0   0000111122222


Q NP_000836.2     363 WEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKEL  442 (908)
Q Consensus       363 ~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~l  442 (908)
                      +++.++                           ..++.++..+|||+++++.++++....              .++..+
T Consensus       267 ~~~~~~---------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~--------------~~~~~~  305 (358)
T 3HUT_A          267 YETLYG---------------------------AIPTLFAAHGYDAVGIMLAAVGRAGPE--------------VTRESL  305 (358)
T ss_dssp             HHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHCTT--------------CCHHHH
T ss_pred             HHHHHC---------------------------CCCCHHHHHHHHHHHHHHHHHHHhCCC--------------CCHHHH
Confidence            221111                           112345678999999999999876431              134567


Q NP_000836.2     443 LGYIRAV-NFNGSAGTPVTFNENGDA-PGRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       443 ~~~l~~~-~f~G~~G~~v~Fd~~G~~-~~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                      .+.|++. .|.|.+| ++.|++++++ ...+.+++++    +++++.+|.|..
T Consensus       306 ~~~l~~~~~~~g~~G-~~~f~~~~~~~~~~~~~~~~~----~~~~~~~~~~~~  353 (358)
T 3HUT_A          306 RDALAATDRYAGVTG-ITRFDPETRETTKILTRLVVR----EGDFRVIDREGH  353 (358)
T ss_dssp             HHHHHTCCSEEETTE-EEEECTTTCCEEECCEEEEEE----TTEEEEC-----
T ss_pred             HHHHHcCCCccCCCe-eEEECCCCCccceeEEEEEEE----CCEEEEecCCCC
Confidence            7778765 6899988 8999986543 4566777776    367888888864


No 72
>5KUH_C Glutamate receptor ionotropic, kainate 2; GluK2EM with LY466195, SIGNALING PROTEIN; HET: LY5; 11.6A {Rattus norvegicus}
Probab=99.54  E-value=4.1e-19  Score=209.95  Aligned_cols=372  Identities=16%  Similarity=0.193  Sum_probs=231.8  Template_Neff=11.700

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCS-RDTYALEQSLTFVQ  121 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~-~~~~a~~~~~~~~~  121 (908)
                      +++++||+++|.++..            .+.....|+++|++++|++++++++..+.+...|+.+ +...+    .+.+.
T Consensus         2 ~~~i~Ig~~~p~sg~~------------~g~~~~~~~~~A~~~in~~~g~~~~~~~~~~~~~~~~~~~~~~----~~~~~   65 (757)
T 5KUH_C            2 THVLRFGGIFEYVESG------------PMGAEELAFRFAVNTINRNRTLLPNTTLTYDTQKINLYDSFEA----SKKAC   65 (757)
T ss_dssp             CEEEEEEEEEEESSSC------------SCCHHHHHHHHHHHHHHHCSSSSSSEEEEEEEEEEETTCHHHH----HHHHH
T ss_pred             CceEEeEEEeecCCCC------------CCcHHHHHHHHHHHHHHcCcccCCCCeeeeeeEecCCCChHHH----HHHHH
Confidence            4689999999998742            3567889999999999998877777888887777654 32211    11111


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +..                   .++++++||+.++..+..++.+++..++|+|++.+.++.+.+  .+++++++.+++..
T Consensus        66 ~~~-------------------~~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~~  124 (757)
T 5KUH_C           66 DQL-------------------SLGVAAIFGPSHSSSANAVQSICNALGVPHIQTRWKHQVSDN--KDSFYVSLYPDFSS  124 (757)
T ss_dssp             HHH-------------------HHCCSCEECCSSHHHHHHHHHHHHHTTCCEEECSCCCCCTTC--CCCSEEEEEECHHH
T ss_pred             HHH-------------------HcCccEEEcCCChHHHHHHHHHHHHHCCCEEEeecCCCCCCC--CCceEEEccCCHHH
Confidence            111                   147899999998888888888999999999998876665443  36889999999988


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .+.++++++.+++|+++++++ ++.++....+.+.+.+.+. ++++... .++  .+..++...+++++. .++++|++.
T Consensus       125 ~~~~l~~~~~~~~~~~v~ii~-~~~~~~~~~~~~~~~~~~~-g~~v~~~-~~~--~~~~~~~~~l~~l~~-~~~~~vv~~  198 (757)
T 5KUH_C          125 LSRAILDLVQFFKWKTVTVVY-DDSTGLIRLQELIKAPSRY-NLRLKIR-QLP--ADTKDAKPLLKEMKR-GKEFHVIFD  198 (757)
T ss_dssp             HHHHHHHHHHHTTCSEEEEEE-SSTHHHHHTHHHHTGGGTS-SCEEEEE-ECC--SSGGGCHHHHHHHHH-TTCCEEEEE
T ss_pred             HHHHHHHHHHHcCCCEEEEEE-eCchHHHHHHHHHhCcccc-CceEEEE-EcC--CCccccHHHHHHHHh-CCCEEEEEE
Confidence            899999999888999999999 5556766677777766664 3555432 232  223456667777763 578999888


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      .....+..+++++++.|+.. .+.|+........... .  .....+.....        +.. ..    ...+....+.
T Consensus       199 ~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~-~--~~~~~~~~~~~--------~~~-~~----~~~~~~~~f~  262 (757)
T 5KUH_C          199 CSHEMAAGILKQALAMGMMTEYYHYIFTTLDLFALDV-E--PYRYSGVNMTG--------FRI-LN----TENTQVSSII  262 (757)
T ss_dssp             SCHHHHHHHHHHHHHTTCCSTTCEEEECCTTGGGBCC-T--TTTTSCCEEEE--------EEC-SC----TTSHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHcCCcCCCeEEEEeccCcccCCc-h--hhcccCcceEE--------EEE-ee----CCChHHHHHH
Confidence            77777888999998888754 2345543211110000 0  00001100000        000 00    0011122233


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM-STIDG  439 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~-~~~~~  439 (908)
                      +.|++.+.....          .+...     .....+..++..+|||++++++|++++....+..  ..|... ...++
T Consensus       263 ~~~~~~~~~~~~----------~~~~~-----~~~~~~~~~~~~~ydav~~~~~al~~~~~~~~~~--~~~~~~~~~~~~  325 (757)
T 5KUH_C          263 EKWSMERLQAPP----------KPDSG-----LLDGFMTTDAALMYDAVHVVSVAVQQFPQMTVSS--LQCNRHKPWRFG  325 (757)
T ss_dssp             HHHHHHHTTSCC----------CSSSC-----BCTTCCCHHHHHHHHHHHHHHHHHHTCTTCCCCC--CCTTSCCCCTTH
T ss_pred             HHHHHhhcCCCC----------CCCCC-----CCCCCccHHHHHHHHHHHHHHHHHHhccccCCCc--cccCCCCcchhH
Confidence            333322210000          00000     0001234567889999999999999876543211  112111 11244


Q NP_000836.2     440 KELLGYIRAVNFNGSAGTPVTFNENGDAPGR--YDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       440 ~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~--~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                      ..+.+.|++..|.|.+| ++.||++|++...  +.++++.    ++.++.||.|....
T Consensus       326 ~~l~~~l~~~~~~g~~G-~i~f~~~~~~~~~~~~~~~~~~----~~~~~~vg~~~~~~  378 (757)
T 5KUH_C          326 TRFMSLIKEAHWEGLTG-RITFNKTNGLRTDFDLDVISLK----EEGLEKIGTWDPAS  378 (757)
T ss_dssp             HHHHHHHHTCEEEETTE-EEECCTTTSEECCCCEEEEEEE----TTEEEEEEEEETTT
T ss_pred             HHHHHHHHhcccCCccc-eeEecccCCeeeeeEEEEEEcc----cccceeeEEEECCC
Confidence            56778888889999988 8999987777654  4444444    35789999998653


No 73
>4EVQ_A Putative ABC transporter subunit, substrate-binding; Structural Genomics, PSI-Biology, Midwest Center; HET: PHB, MSE, SO4, GOL; 1.4A {Rhodopseudomonas palustris}
Probab=99.54  E-value=4.1e-19  Score=190.38  Aligned_cols=352  Identities=16%  Similarity=0.137  Sum_probs=219.3  Template_Neff=11.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||+++|..+...          ..+.....+++.+++++|.   ...|+++++...|+.+++..    ..+
T Consensus        10 ~~~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~~---~~~g~~v~~~~~d~~~~~~~----~~~   72 (375)
T 4EVQ_A           10 SYAQAGALKVGLLLPYSGTYA----------PLGEAITRGLELYVQSQGG---KLGGRSISFVKVDDESAPPK----ATE   72 (375)
T ss_dssp             -----CCEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHTTT---EETTEEEEEEEEECTTCHHH----HHH
T ss_pred             cccCCCcEEEEEEeCCCCCch----------hhhHHHHHHHHHHHHhcCC---CcCCEEEEEEEecCCCChHH----HHH
Confidence            446678999999999876421          2456788899999998753   22367788777776554322    233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+++++.                  .++++++|++.++.....+...+...++|+|.+....+.+......++++++.++
T Consensus        73 ~~~~l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  134 (375)
T 4EVQ_A           73 LTTKLIQ------------------SEKADVLIGTVHSGVAMAMVKIAREDGIPTIVPNAGADIITRAMCAPNVFRTSFA  134 (375)
T ss_dssp             HHHCCCC------------------CSCCSEEEECSSHHHHHHHHHHHHHHCCCEEESSCCCGGGGTTTCCTTEEESSCC
T ss_pred             HHHHHHH------------------cCCCCEEEEecCHHHHHHHHHHHHHhCCCEEEcCCCChhhcccccCCCEEEeecC
Confidence            3333332                  1578999987766655666677788899999887665443322235678888898


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      +...++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  ....+....+++++. .++|++
T Consensus       135 ~~~~~~~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i  210 (375)
T 4EVQ_A          135 NGQIGRATGDAMIKAGLKKAVTVTWKYAAGEEMVSGFKKSFTAG-KGEVVKDITIA--FPDVEFQSALAEIAS-LKPDCV  210 (375)
T ss_dssp             HHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCCCCHHHHHHHHH-HCCSEE
T ss_pred             hhHHHHHHHHHHHHcCCCeEEEEeeCChHhHHHHHHHHHHHHhC-CCeEeeEEEec--CCCcchHHHHHHHHh-hCCCEE
Confidence            88888899999887899999999866667777888888888765 35443322222  122345566677763 478888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVW  358 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  358 (908)
                      ++...+..+..+++++++.|+.  ..+++.+.|.....  ........+.+.....          ..   ....+....
T Consensus       211 i~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~----------~~---~~~~~~~~~  273 (375)
T 4EVQ_A          211 YAFFSGGGALKFIKDYAAANLG--IPLWGPGFLTDGVE--AAAGPAGDGIKTVLHY----------VS---DLDNAENQA  273 (375)
T ss_dssp             EEECCTHHHHHHHHHHHHTTCC--CCEEEEGGGTTTTH--HHHGGGGTTCEEEESC----------CT---TCCSHHHHH
T ss_pred             EEEeecchHHHHHHHHHHCCCC--CCEEeccccchhHH--HHHccccCCcEEEEec----------CC---CCCCHHHHH
Confidence            8776566677888988888874  34554432221100  0001112222211110          00   000011112


Q NP_000836.2     359 FAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTID  438 (908)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~  438 (908)
                      |.+.+++.++                           ..++.++..+||++++++.|++++...             ..+
T Consensus       274 f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~~-------------~~~  313 (375)
T 4EVQ_A          274 FVKSFEAAYK---------------------------IPPDVFAVQGWDAGQLLDAGVKAVGGD-------------VAK  313 (375)
T ss_dssp             HHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHTTTC-------------TTC
T ss_pred             HHHHHHHHHC---------------------------CCCCHHHHHHHHHHHHHHHHHHHhCCC-------------ccc
Confidence            2222222111                           112356778999999999999987531             123


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHW  491 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~  491 (908)
                      ++.+.+.|++..|.|.+| ++.||++|++...+.+.+++    ++.++.+|.+
T Consensus       314 ~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~i~~~~----~~~~~~~~~~  361 (375)
T 4EVQ_A          314 RKELNAAMAAASFASPRG-PFKLSAAHNPVQNFYLRELK----GGKSVNLGLA  361 (375)
T ss_dssp             HHHHHHHHHTCEEEETTE-EEEBCTTSCBCCCEEEEEEE----TTEEEEEEEE
T ss_pred             HHHHHHHHHcCCCCCCCc-ceEeCCCCCeeeeEEEEEEE----CCeEEEeEEe
Confidence            456778888888999999 89999888877778888887    3567777766


No 74
>4EVQ_B Putative ABC transporter subunit, substrate-binding; Structural Genomics, PSI-Biology, Midwest Center; HET: GOL, PHB, SO4; 1.4A {Rhodopseudomonas palustris}
Probab=99.54  E-value=4.1e-19  Score=190.38  Aligned_cols=352  Identities=16%  Similarity=0.137  Sum_probs=222.2  Template_Neff=11.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||+++|..+...          ..+.....+++.+++++|.   ...|+++++...|+.+++..    ..+
T Consensus        10 ~~~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~~---~~~g~~v~~~~~d~~~~~~~----~~~   72 (375)
T 4EVQ_B           10 SYAQAGALKVGLLLPYSGTYA----------PLGEAITRGLELYVQSQGG---KLGGRSISFVKVDDESAPPK----ATE   72 (375)
T ss_dssp             CHHHHCCEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHTTT---EETTEEEEEEEEECTTCHHH----HHH
T ss_pred             cccCCCcEEEEEEeCCCCCch----------hhhHHHHHHHHHHHHhcCC---CcCCEEEEEEEecCCCChHH----HHH
Confidence            446678999999999876421          2456788899999998753   22367788777776554322    233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+++++.                  .++++++|++.++.....+...+...++|+|.+....+.+......++++++.++
T Consensus        73 ~~~~l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  134 (375)
T 4EVQ_B           73 LTTKLIQ------------------SEKADVLIGTVHSGVAMAMVKIAREDGIPTIVPNAGADIITRAMCAPNVFRTSFA  134 (375)
T ss_dssp             HHHCCCC------------------CSCCSEEEECSSHHHHHHHHHHHHHHCCCEEESSCCCGGGGTTTCCTTEEESSCC
T ss_pred             HHHHHHH------------------cCCCCEEEEecCHHHHHHHHHHHHHhCCCEEEcCCCChhhcccccCCCEEEeecC
Confidence            3333332                  1578999987766655666677788899999887665443322235678888898


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      +...++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  ....+....+++++. .++|++
T Consensus       135 ~~~~~~~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i  210 (375)
T 4EVQ_B          135 NGQIGRATGDAMIKAGLKKAVTVTWKYAAGEEMVSGFKKSFTAG-KGEVVKDITIA--FPDVEFQSALAEIAS-LKPDCV  210 (375)
T ss_dssp             HHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCCCCHHHHHHHHH-HCCSEE
T ss_pred             hhHHHHHHHHHHHHcCCCeEEEEeeCChHhHHHHHHHHHHHHhC-CCeEeeEEEec--CCCcchHHHHHHHHh-hCCCEE
Confidence            88888899999887899999999866667777888888888765 35443322222  122345566677763 478888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVW  358 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  358 (908)
                      ++...+..+..+++++++.|+.  ..+++.+.|.....  ........+.+.....          ..   ....+....
T Consensus       211 i~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~----------~~---~~~~~~~~~  273 (375)
T 4EVQ_B          211 YAFFSGGGALKFIKDYAAANLG--IPLWGPGFLTDGVE--AAAGPAGDGIKTVLHY----------VS---DLDNAENQA  273 (375)
T ss_dssp             EEECCTHHHHHHHHHHHHTTCC--CCEEEEGGGTTTTH--HHHGGGGTTCEEEESC----------CT---TCCSHHHHH
T ss_pred             EEEeecchHHHHHHHHHHCCCC--CCEEeccccchhHH--HHHccccCCcEEEEec----------CC---CCCCHHHHH
Confidence            8776566677888988888874  34554432221100  0001112222211110          00   000011112


Q NP_000836.2     359 FAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTID  438 (908)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~  438 (908)
                      |.+.+++.++                           ..++.++..+||++++++.|++++...             ..+
T Consensus       274 f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~~-------------~~~  313 (375)
T 4EVQ_B          274 FVKSFEAAYK---------------------------IPPDVFAVQGWDAGQLLDAGVKAVGGD-------------VAK  313 (375)
T ss_dssp             HHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHTTTC-------------TTC
T ss_pred             HHHHHHHHHC---------------------------CCCCHHHHHHHHHHHHHHHHHHHhCCC-------------ccc
Confidence            2222222111                           112356778999999999999987531             123


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHW  491 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~  491 (908)
                      ++.+.+.|++..|.|.+| ++.||++|++...+.+.+++    ++.++.+|.+
T Consensus       314 ~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~i~~~~----~~~~~~~~~~  361 (375)
T 4EVQ_B          314 RKELNAAMAAASFASPRG-PFKLSAAHNPVQNFYLRELK----GGKSVNLGLA  361 (375)
T ss_dssp             HHHHHHHHHTCEEEETTE-EEEBCTTSCBCCCEEEEEEE----TTEEEEEEEE
T ss_pred             HHHHHHHHHcCCCCCCCc-ceEeCCCCCeeeeEEEEEEE----CCeEEEeEEe
Confidence            456778888888999999 89999888877778888887    3567777766


No 75
>4N0Q_B Leu/Ile/Val-binding protein homolog 3; structural genomics, NIAID, National Institute; HET: LEU; 2.3A {Brucella melitensis}
Probab=99.54  E-value=4.2e-19  Score=188.61  Aligned_cols=336  Identities=17%  Similarity=0.229  Sum_probs=214.3  Template_Neff=11.900

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ..+++||++.|+++...          ..+.....+++.|++++|+.+++. |.++++.+.|+.+++..    ..+.+++
T Consensus         8 ~~~~~ig~~~p~sg~~~----------~~~~~~~~g~~~a~~~~n~~~~~~-g~~i~~~~~d~~~~~~~----~~~~~~~   72 (354)
T 4N0Q_B            8 HADITIGVIAPLTGPVA----------AFGDQVKKGAETAVEVINKAGGIK-GEKVVLKFADDAGEPKQ----GVSAANQ   72 (354)
T ss_dssp             -CCEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHHTTTBT-TBCEEEEEEECTTCHHH----HHHHHHH
T ss_pred             ccCeEEEEEEcCCCCcH----------HHHHHHHHHHHHHHHHHHHccCCC-CeeEEEEEecCCCCHHH----HHHHHHH
Confidence            35789999999987642          366788999999999999876543 67888888887665432    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   ++++++|++.++.....+...+...++|+|.+....+.+... .+++++++.+++...
T Consensus        73 l~~-------------------~~v~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~~~~  132 (354)
T 4N0Q_B           73 IVG-------------------DGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTAR-GLENVFRTCGRDGQQ  132 (354)
T ss_dssp             HHH-------------------TTCCEEEECCSHHHHHHHHHHHHHTTCEEEESSCCCGGGGSS-CCSSEEESSCCHHHH
T ss_pred             HHh-------------------CCCCEEEEcCCcccHHHHHHHHHHcCCEEEecccCCcchhhc-CCCceeecCCChHHH
Confidence            332                   478899987766655566677788899999987655443321 256788999998888


Q NP_000836.2     203 AQAMVDIV-TALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       203 ~~~~~~~l-~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      ++.+++++ ++++|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++|++++.
T Consensus       133 ~~~~~~~l~~~~~~~~i~~l~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~vi~~  208 (354)
T 4N0Q_B          133 AEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKG-GITEVHYDSVT--PGDKDFSALVTKLKS-AGAEVVYFG  208 (354)
T ss_dssp             HHHHHHHHHHHCTTSCEEEEECSSHHHHHHHHHHHHHHHHT-TCCCSEEEECC--TTCCCCHHHHHHHHH-TTCSEEEEE
T ss_pred             HHHHHHHHHHhcCCCEEEEEECCCHhhHHHHHHHHHHHHhC-CCeeeEEEeeC--CCCCChHHHHHHHHH-CCCCEEEEe
Confidence            99999988 45689999999976667777888888888775 45544322222  122344555666653 578888777


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAE  361 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  361 (908)
                      ..+..+..+++++++.|+.  +.|++.+.|...... ........+.......           .   .   ...+.+.+
T Consensus       209 ~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~---~---~~~~~~~~  268 (354)
T 4N0Q_B          209 GYHAEGGLLSRQLHDAGMQ--ALVLGGEGLSNTEYW-AIGGTNAQGTLFTNAK-----------D---A---TKNPAAKD  268 (354)
T ss_dssp             SCHHHHHHHHHHHHHTTCC--CEEEECGGGCSHHHH-HHHGGGGTTCEEEEEC-----------C---G---GGSGGGHH
T ss_pred             cCchhHHHHHHHHHHcCCC--cEEEeccccCCHHHH-HhhcccccCcEEecCC-----------c---c---CCCHHHHH
Confidence            6566677888888888773  466665544322110 0001111222111100           0   0   01111222


Q NP_000836.2     362 FWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKE  441 (908)
Q Consensus       362 ~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~  441 (908)
                      +.++ +.. ..                       ..++.++..+|||++++++|++++...              .+++.
T Consensus       269 f~~~-~~~-~~-----------------------~~~~~~~~~~yda~~~~~~a~~~~~~~--------------~~~~~  309 (354)
T 4N0Q_B          269 AIQA-LKA-KN-----------------------IPAEAFTMNAYAAVEVIKAGIERAGST--------------DDSAA  309 (354)
T ss_dssp             HHHH-HHH-TT-----------------------CCCCHHHHHHHHHHHHHHHHHHHHTCS--------------SCHHH
T ss_pred             HHHH-HHH-cC-----------------------CCCChHHHHHHHHHHHHHHHHHHhCCC--------------CCHHH
Confidence            2221 110 00                       112356778999999999999886431              13445


Q NP_000836.2     442 LLGYIRA-VNFNGSAGTPVTFNENGDAP-GRYDIFQYQ  477 (908)
Q Consensus       442 l~~~l~~-~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~  477 (908)
                      +.++|++ ..|.|.+| .+.|+++|++. ..+.+++++
T Consensus       310 ~~~~l~~~~~~~g~~g-~i~f~~~g~~~~~~~~i~~~~  346 (354)
T 4N0Q_B          310 VAKALHDGKPIETAIG-TLTYSETGDLSSPSFDIFKWD  346 (354)
T ss_dssp             HHHHHTSSCCEEETTE-EECBCTTSCBSSCCEEEEEEE
T ss_pred             HHHHHhcCCCCcccee-EEEeCCCCCCCCCeeEEEEEE
Confidence            7777865 57899988 89999888875 356777776


No 76
>4N0Q_C Leu/Ile/Val-binding protein homolog 3; structural genomics, NIAID, National Institute; HET: LEU; 2.3A {Brucella melitensis}
Probab=99.54  E-value=4.2e-19  Score=188.61  Aligned_cols=336  Identities=17%  Similarity=0.229  Sum_probs=213.8  Template_Neff=11.900

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ..+++||++.|+++...          ..+.....+++.|++++|+.+++. |.++++.+.|+.+++..    ..+.+++
T Consensus         8 ~~~~~ig~~~p~sg~~~----------~~~~~~~~g~~~a~~~~n~~~~~~-g~~i~~~~~d~~~~~~~----~~~~~~~   72 (354)
T 4N0Q_C            8 HADITIGVIAPLTGPVA----------AFGDQVKKGAETAVEVINKAGGIK-GEKVVLKFADDAGEPKQ----GVSAANQ   72 (354)
T ss_dssp             --CEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHHTTCSS-SCCEEEEEEECTTCHHH----HHHHHHH
T ss_pred             ccCeEEEEEEcCCCCcH----------HHHHHHHHHHHHHHHHHHHccCCC-CeeEEEEEecCCCCHHH----HHHHHHH
Confidence            35789999999987642          366788999999999999876543 67888888887665432    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   ++++++|++.++.....+...+...++|+|.+....+.+... .+++++++.+++...
T Consensus        73 l~~-------------------~~v~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~~~~  132 (354)
T 4N0Q_C           73 IVG-------------------DGIKFVVGLVTTGVAVPVSDVLSENGVLMVTPTATGPDLTAR-GLENVFRTCGRDGQQ  132 (354)
T ss_dssp             HHH-------------------TTCCEEEECCSHHHHHHHHHHHHHTTCEEEESSCCCGGGSSS-CCSSEEESSCCHHHH
T ss_pred             HHh-------------------CCCCEEEEcCCcccHHHHHHHHHHcCCEEEecccCCcchhhc-CCCceeecCCChHHH
Confidence            332                   478899987766655566677788899999987655443321 256788999998888


Q NP_000836.2     203 AQAMVDIV-TALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       203 ~~~~~~~l-~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      ++.+++++ ++++|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++|++++.
T Consensus       133 ~~~~~~~l~~~~~~~~i~~l~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~vi~~  208 (354)
T 4N0Q_C          133 AEVMADYVLKNMKDKKVAVIHDKGAYGKGLADAFKAAINKG-GITEVHYDSVT--PGDKDFSALVTKLKS-AGAEVVYFG  208 (354)
T ss_dssp             HHHHHHHHHHHCTTSCEEEEECSSHHHHHHHHHHHHHHHHH-TCCCSEEEECC--TTCCCCHHHHHHHHH-TTCSEEEEE
T ss_pred             HHHHHHHHHHhcCCCEEEEEECCCHhhHHHHHHHHHHHHhC-CCeeeEEEeeC--CCCCChHHHHHHHHH-CCCCEEEEe
Confidence            99999988 45689999999976667777888888888775 45544322222  122344555666653 578888777


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAE  361 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  361 (908)
                      ..+..+..+++++++.|+.  +.|++.+.|...... ........+.......           .   .   ...+.+.+
T Consensus       209 ~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~---~---~~~~~~~~  268 (354)
T 4N0Q_C          209 GYHAEGGLLSRQLHDAGMQ--ALVLGGEGLSNTEYW-AIGGTNAQGTLFTNAK-----------D---A---TKNPAAKD  268 (354)
T ss_dssp             SCHHHHHHHHHHHHHTTCC--CEEEECGGGCSHHHH-HHHGGGGTTCEEEEEC-----------C---S---TTSGGGHH
T ss_pred             cCchhHHHHHHHHHHcCCC--cEEEeccccCCHHHH-HhhcccccCcEEecCC-----------c---c---CCCHHHHH
Confidence            6566677888888888773  466665544322110 0001111222111100           0   0   01111222


Q NP_000836.2     362 FWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKE  441 (908)
Q Consensus       362 ~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~  441 (908)
                      +.++ +.. ..                       ..++.++..+|||++++++|++++...              .+++.
T Consensus       269 f~~~-~~~-~~-----------------------~~~~~~~~~~yda~~~~~~a~~~~~~~--------------~~~~~  309 (354)
T 4N0Q_C          269 AIQA-LKA-KN-----------------------IPAEAFTMNAYAAVEVIKAGIERAGST--------------DDSAA  309 (354)
T ss_dssp             HHHH-HHH-TT-----------------------CCCCHHHHHHHHHHHHHHHHHHHHTCS--------------SCHHH
T ss_pred             HHHH-HHH-cC-----------------------CCCChHHHHHHHHHHHHHHHHHHhCCC--------------CCHHH
Confidence            2221 110 00                       112356778999999999999886431              13445


Q NP_000836.2     442 LLGYIRA-VNFNGSAGTPVTFNENGDAP-GRYDIFQYQ  477 (908)
Q Consensus       442 l~~~l~~-~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~  477 (908)
                      +.++|++ ..|.|.+| .+.|+++|++. ..+.+++++
T Consensus       310 ~~~~l~~~~~~~g~~g-~i~f~~~g~~~~~~~~i~~~~  346 (354)
T 4N0Q_C          310 VAKALHDGKPIETAIG-TLTYSETGDLSSPSFDIFKWD  346 (354)
T ss_dssp             HHHHHHSCCCEEETTE-EECBCTTSCBSSCCEEEEEEE
T ss_pred             HHHHHhcCCCCcccee-EEEeCCCCCCCCCeeEEEEEE
Confidence            7777865 57899988 89999888875 356777776


No 77
>3SAJ_C Glutamate receptor 1; Rossmann fold, ion channel, membrane; HET: BMA, MAN, NAG; 2.5A {Rattus norvegicus}
Probab=99.54  E-value=4.5e-19  Score=190.74  Aligned_cols=357  Identities=17%  Similarity=0.268  Sum_probs=218.4  Template_Neff=11.900

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||+++|.++                .....|+++|++++|+++++++++++ +...|+..        ..+.+
T Consensus         6 ~~~~~i~Ig~~~~~~~----------------~~~~~~~~~a~~~~n~~~~~~~~~~~-~~~~d~~~--------~~~~~   60 (384)
T 3SAJ_C            6 AMPNNIQIGGLFPNQQ----------------SQEHAAFRFALSQLTEPPKLLPQIDI-VNISDSFE--------MTYRF   60 (384)
T ss_pred             cCCCCEEEEEEcCCCc----------------HHHHHHHHHHHHHHHHcCCCCCCEEE-EEEcCcHH--------HHHHH
Confidence            4567899999999875                24668999999999987766555555 44444321        11122


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      .+++.                   ++++++||+.++..+..++..+...++|+|++.+....     ..++++. .+++ 
T Consensus        61 ~~~~~-------------------~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~-----~~~~~~~-~~~~-  114 (384)
T 3SAJ_C           61 CSQFS-------------------KGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDT-----SNQFVLQ-LRPE-  114 (384)
T ss_pred             HHHHh-------------------cCCCEEECCCCHHHHHHHHHHHHHhCCCEEeCCCCCCC-----CCCccee-cCHH-
Confidence            22221                   47889999888877777788889999999998754321     1233333 4333 


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                       .+.++++++++++|++|++++ ++.++....+.+++.+++. ++++.....++  .+..++...+++++. .++|+|++
T Consensus       115 -~~~~~~~~~~~~~~~~v~ii~-~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~  188 (384)
T 3SAJ_C          115 -LQEALISIIDHYKWQTFVYIY-DADRGLSVLQRVLDTAAEK-NWQVTAVNILT--TTEEGYRMLFQDLEK-KKERLVVV  188 (384)
T ss_pred             -HHHHHHHHHHHhCCCEEEEEe-cChhhHHHHHHHHHHHHHc-CCeEEEEEecC--CCCCCcHHHHHHHHH-hCCCEEEE
Confidence             678888888888999999999 6677877788888887775 35554433332  122456666777763 57899988


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSD-SWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVW  358 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~-~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  358 (908)
                      .........+++++++.|+.. .+.|+..+ .|.....  ........+......          + .    ...+....
T Consensus       189 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~~~~~~----------~-~----~~~~~~~~  251 (384)
T 3SAJ_C          189 DCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL--NKFKESGANVTGFQL----------V-N----YTDTIPAR  251 (384)
T ss_pred             eCCHHHHHHHHHHHHHCCCCCCCeEEEEeCCCcCCCch--HHhhhcccccceeEe----------e-C----CCCcccHH
Confidence            877777788999998888753 46677654 2322110  000000111111000          0 0    00111122


Q NP_000836.2     359 FAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG----YIGLCPRM  434 (908)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~----~~~~~~~~  434 (908)
                      +.+.|++.+..             .|....      ...+..++..+|||++++++++++.....+..    ....|...
T Consensus       252 f~~~~~~~~~~-------------~~~~~~------~~~~~~~~~~~ydav~~~~~al~~~~~~~~~~~~~~~~~~c~~~  312 (384)
T 3SAJ_C          252 IMQQWRTSDSR-------------DHTRVD------WKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLAN  312 (384)
T ss_pred             HHHHHHHHHCC-------------CCCCCC------CCCCChHHHHHHHHHHHHHHHHHHHHhcCCCCCCCCCCCccCCC
Confidence            33333333221             010000      01234567889999999999999987543210    01122211


Q NP_000836.2     435 ---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       435 ---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                         ...++..+.+.|++..|.|.+| ++.||++|++.. .+.+++++    ++.++.||.|+...
T Consensus       313 ~~~~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~  372 (384)
T 3SAJ_C          313 PAVPWGQGIDIQRALQQVRFEGLTG-NVQFNEKGRRTNYTLHVIEMK----HDGIRKIGYWNEDD  372 (384)
T ss_pred             CCCCccCHHHHHHHHhcCCcccCCc-cEEEcCCCCCCCeeEEEEEee----CCcEEEeEEEeCCC
Confidence               0114456778888889999998 899999998753 56666665    35789999998653


No 78
>6E7R_B Glutamate receptor ionotropic, NMDA 1; NMDA Receptor, Ion channel, Allosteric; HET: HYS, CL, MAN, NAG, BMA; 2.1A {Xenopus laevis}
Probab=99.53  E-value=6e-19  Score=188.06  Aligned_cols=348  Identities=15%  Similarity=0.202  Sum_probs=223.3  Template_Neff=12.000

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ++++||+++|..                  ....|++.|++++|+.++++ |.++++... +.+++..    ..+.+.++
T Consensus         2 ~~i~ig~~~~~~------------------~~~~~~~~a~~~in~~~~~~-g~~i~l~~~-~~~~~~~----~~~~~~~l   57 (363)
T 6E7R_B            2 PSIGIAVILVGT------------------SDEVAIKDAHEKDDFHHLSV-VPRVELVAM-NETDPKS----IITRICDL   57 (363)
T ss_dssp             CEEEEEEEEESS------------------CCHHHHHHHTTGGGGCCSSS-EEEEEEEEE-CCCSHHH----HHHHHHHH
T ss_pred             CceeEEEEEeCC------------------chhHHHHHHHHhcCCCCCcc-CCcEEEEEc-CCCCHHH----HHHHHHHH
Confidence            578999998621                  35678999999999877654 567777666 4444332    22333333


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVI--GAAASSV-SIMVANILRLFKIPQISYASTA-PELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vI--g~~~s~~-~~~va~~~~~~~iP~Is~~~~~-~~l~~~~~~~~~~~~~~~~  199 (908)
                      +.                  .++++++|  |+.++.. +..+...+...++|+|++.+.. ..+++...+++++++.+++
T Consensus        58 ~~------------------~~~v~~vi~~g~~~s~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~  119 (363)
T 6E7R_B           58 MS------------------DRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSI  119 (363)
T ss_dssp             HH------------------HSCEEEEEEEESSCCTHHHHHHHHHHHHHTCCEEEEEGGGGSCCCSCCTTCCEEESSCCH
T ss_pred             Hh------------------hCCceEEEEcCCCCHHHHHHHHHHHHHhhCCCEEEecCCCcccccCCCccceeEEcCCCH
Confidence            32                  14789999  8877753 6677778888999999887643 2333333578999999999


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPR-PGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~-~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ...++++++++.+++|+++++++.+++++....+.+++.+++. ++++.....++.... ..++...+++++. .++++|
T Consensus       120 ~~~~~~~~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~i~~-~~~~~v  197 (363)
T 6E7R_B          120 EQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENS-FVGWELEEVLLLDMSLDDGDSKIQNQLKK-LQSPII  197 (363)
T ss_dssp             HHHHHHHHHHHHHTTCCEEEEEECSSTTHHHHHHHHHHHHHTS-SSCCEEEEEEECCTTSCCTTCHHHHHHTT-CCCSEE
T ss_pred             HHHHHHHHHHHHHcCCeEEEEEEEcCCChHHHHHHHHHHHhhc-CCCeEEEEEEEecCCCCCchHHHHHHHHh-CCCCEE
Confidence            9899999999988899999999987778887888888877765 355543222211011 2245566777763 578988


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      ++......+..+++++++.|+.. ++.|+..+.+...... . ......+.+.+                          
T Consensus       198 v~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~-~~~~~~g~~~~--------------------------  249 (363)
T 6E7R_B          198 LLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDT-V-PSEFPTGLISV--------------------------  249 (363)
T ss_dssp             EEESCHHHHHHHHHHHHHTTCSSTTCEEEECHHHHCSTTC-C-CTTSCTTCEEE--------------------------
T ss_pred             EEeCCHHHHHHHHHHHHHcCCCCCCeEEEeecCCCCCCCC-C-CccCCCceEEE--------------------------
Confidence            88877777788899888888753 4567665422211000 0 00000110000                          


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG--YIGLCPRM-  434 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~--~~~~~~~~-  434 (908)
                      .+    . .+                              ...++..+|||++++++|++++....+..  ....|... 
T Consensus       250 ~~----~-~~------------------------------~~~~~~~~ydav~~~~~al~~~~~~~~~~~~~~~~c~~~~  294 (363)
T 6E7R_B          250 SY----D-EW------------------------------DYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTH  294 (363)
T ss_dssp             EC----S-SS------------------------------SSCHHHHHHHHHHHHHHHHHHHHHHHSCCCCCCSCSTTTT
T ss_pred             ee----c-cc------------------------------ccChhHHHHHHHHHHHHHHHHHHhhcCCCCCCCccccCCC
Confidence            00    0 00                              01235678999999999999987532110  01122211 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                        ...++..+.++|++..|.|  | ++.|+++|++. ..+.|++++.   ...++.||.|+... ++...+.|+
T Consensus       295 ~~~~~~~~~l~~~l~~~~~~g--g-~i~f~~~g~~~~~~~~i~~~~~---~~~~~~vg~w~~~~-l~~~~~~w~  361 (363)
T 6E7R_B          295 EKRIYQSNMLNRYLINVTFEG--R-DLSFSEDGYQMHPKLVIILLNK---ERKWERVGKWKDKS-LQMKYYVWP  361 (363)
T ss_dssp             GGGGGCCCTTHHHHTSCEETT--E-ECCBCTTSBBSSCCEEEEEECT---TSCEEEEEEEETTE-EEESCSSCC
T ss_pred             cccchhhHHHHHHHcceEecC--e-eeeeCCCCccccceEEEEEeeC---CCceEEEEEEECCe-eEeeceecC
Confidence              1124556778888888987  7 89999999875 5788888873   25688999998762 333346663


No 79
>6E7S_D Glutamate receptor ionotropic, NMDA 1; NMDA Receptor, Ion channel, Allosteric; HET: MAN, HZ4, NAG, BMA; 2.72A {Xenopus laevis}
Probab=99.53  E-value=6e-19  Score=188.06  Aligned_cols=348  Identities=15%  Similarity=0.202  Sum_probs=223.3  Template_Neff=12.000

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ++++||+++|..                  ....|++.|++++|+.++++ |.++++... +.+++..    ..+.+.++
T Consensus         2 ~~i~ig~~~~~~------------------~~~~~~~~a~~~in~~~~~~-g~~i~l~~~-~~~~~~~----~~~~~~~l   57 (363)
T 6E7S_D            2 PSIGIAVILVGT------------------SDEVAIKDAHEKDDFHHLSV-VPRVELVAM-NETDPKS----IITRICDL   57 (363)
T ss_dssp             CEEEEEEEEESS------------------CCHHHHHHHHTTTTTCCSSC-EEEEEEEEE-SCCSHHH----HHHHHHHH
T ss_pred             CceeEEEEEeCC------------------chhHHHHHHHHhcCCCCCcc-CCcEEEEEc-CCCCHHH----HHHHHHHH
Confidence            578999998621                  35678999999999877654 567777666 4444332    22333333


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVI--GAAASSV-SIMVANILRLFKIPQISYASTA-PELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vI--g~~~s~~-~~~va~~~~~~~iP~Is~~~~~-~~l~~~~~~~~~~~~~~~~  199 (908)
                      +.                  .++++++|  |+.++.. +..+...+...++|+|++.+.. ..+++...+++++++.+++
T Consensus        58 ~~------------------~~~v~~vi~~g~~~s~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~  119 (363)
T 6E7S_D           58 MS------------------DRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPSI  119 (363)
T ss_dssp             HH------------------HSCEEEEEEECSSCCTHHHHHHHHHHHHHTCCEEEEEGGGGSCCCSCCTTCCEEESSCCH
T ss_pred             Hh------------------hCCceEEEEcCCCCHHHHHHHHHHHHHhhCCCEEEecCCCcccccCCCccceeEEcCCCH
Confidence            32                  14789999  8877753 6677778888999999887643 2333333578999999999


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPR-PGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~-~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ...++++++++.+++|+++++++.+++++....+.+++.+++. ++++.....++.... ..++...+++++. .++++|
T Consensus       120 ~~~~~~~~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~i~~-~~~~~v  197 (363)
T 6E7S_D          120 EQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENS-FVGWELEEVLLLDMSLDDGDSKIQNQLKK-LQSPII  197 (363)
T ss_dssp             HHHHHHHHHHHHHTTCCEEEEEECSSTTHHHHHHHHHHHHHSC-SSCCEEEEEEECCTTSCCTTCHHHHHHTT-CCCSEE
T ss_pred             HHHHHHHHHHHHHcCCeEEEEEEEcCCChHHHHHHHHHHHhhc-CCCeEEEEEEEecCCCCCchHHHHHHHHh-CCCCEE
Confidence            9899999999988899999999987778887888888877765 355543222211011 2245566777763 578988


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      ++......+..+++++++.|+.. ++.|+..+.+...... . ......+.+.+                          
T Consensus       198 v~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~-~~~~~~g~~~~--------------------------  249 (363)
T 6E7S_D          198 LLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDT-V-PSEFPTGLISV--------------------------  249 (363)
T ss_dssp             EEESCHHHHHHHHHHHHHTTCSSTTCEEEECHHHHCSTTC-C-CTTSCTTCEEE--------------------------
T ss_pred             EEeCCHHHHHHHHHHHHHcCCCCCCeEEEeecCCCCCCCC-C-CccCCCceEEE--------------------------
Confidence            88877777788899888888753 4567665422211000 0 00000110000                          


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG--YIGLCPRM-  434 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~--~~~~~~~~-  434 (908)
                      .+    . .+                              ...++..+|||++++++|++++....+..  ....|... 
T Consensus       250 ~~----~-~~------------------------------~~~~~~~~ydav~~~~~al~~~~~~~~~~~~~~~~c~~~~  294 (363)
T 6E7S_D          250 SY----D-EW------------------------------DYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNTH  294 (363)
T ss_dssp             EC----T-TS------------------------------SSCHHHHHHHHHHHHHHHHHHHHHHHSCCCCCCSCSTTTT
T ss_pred             ee----c-cc------------------------------ccChhHHHHHHHHHHHHHHHHHHhhcCCCCCCCccccCCC
Confidence            00    0 00                              01235678999999999999987532110  01122211 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                        ...++..+.++|++..|.|  | ++.|+++|++. ..+.|++++.   ...++.||.|+... ++...+.|+
T Consensus       295 ~~~~~~~~~l~~~l~~~~~~g--g-~i~f~~~g~~~~~~~~i~~~~~---~~~~~~vg~w~~~~-l~~~~~~w~  361 (363)
T 6E7S_D          295 EKRIYQSNMLNRYLINVTFEG--R-DLSFSEDGYQMHPKLVIILLNK---ERKWERVGKWKDKS-LQMKYYVWP  361 (363)
T ss_dssp             TTTTTCCSTTHHHHTSCEETT--E-ECCBCTTSBBSSCCEEEEEECT---TSCEEEEEEEETTE-EEESCSSCC
T ss_pred             cccchhhHHHHHHHcceEecC--e-eeeeCCCCccccceEEEEEeeC---CCceEEEEEEECCe-eEeeceecC
Confidence              1124556778888888987  7 89999999875 5788888873   25688999998762 333346663


No 80
>3HSY_B Glutamate receptor 2; GLUTAMATE RECEPTOR, LIGAND-GATED ION CHANNEL; HET: BMA, NAG, SO4; 1.75A {Rattus norvegicus}
Probab=99.53  E-value=6.1e-19  Score=188.94  Aligned_cols=357  Identities=15%  Similarity=0.172  Sum_probs=218.5  Template_Neff=12.200

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI-LDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~-~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ++++||+++|.++.                ....|+++|++++|+.     |+++++.+ .|+.+++..    +.+.+.+
T Consensus         1 ~~i~Ig~~~~~~~~----------------~~~~~~~~a~~~~n~~-----g~~i~~~~~~~~~~~~~~----~~~~~~~   55 (376)
T 3HSY_B            1 NSIQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSFA----VTNAFCS   55 (376)
T ss_dssp             CEEEEEEEEETTCH----------------HHHHHHHHHHHHHCCS-----SCEEEEEEEEECTTCHHH----HHHHHHH
T ss_pred             CceeEEEEecCCCh----------------HHHHHHHHHHHHhcCC-----CceeceeEEecCCCChHH----HHHHHHH
Confidence            36899999998752                4678999999999975     35677765 344444332    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   ++++++||+.++.....++.+++..++|+|++.....     ..+++++++.|+   .
T Consensus        56 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~p~---~  108 (376)
T 3HSY_B           56 QFS-------------------RGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPD---L  108 (376)
T ss_dssp             HHH-------------------HTCSEEEECCCTTTHHHHHHHHHHHTCEEEECSCCCS-----SCCTTEEECSCC---C
T ss_pred             HHh-------------------cCeeEEEecCChHHHHHHHHHHhhcCCeEEecCCCCC-----CCCCcEEEecCC---H
Confidence            332                   4788999998887777888889999999998764332     246889999887   3


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE--PRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~--~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ++++++++.+++|+++++++.++ ++....+.+.+.+++. ++++......+..  .+..++...+++++. .++++|++
T Consensus       109 ~~~~~~~l~~~~~~~v~il~~~~-~~~~~~~~~~~~~~~~-~~~v~~~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vv~  185 (376)
T 3HSY_B          109 KGALLSLIEYYQWDKFAYLYDSD-RGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKERRVIL  185 (376)
T ss_dssp             HHHHHHHHHHTTCCEEEEEECTT-TCSHHHHHHHHHHHHH-TCEEEEEEGGGTTSTTHHHHHHHHHCCCCC-SCCCEEEE
T ss_pred             HHHHHHHHHHhCCCEEEEEEeCc-chHHHHHHHHHHHhhc-CceEEEEEeecCCCCCCccchHHHHHHccc-cCCcEEEE
Confidence            67778888888999999999665 7777777777777664 3555432221100  112345666777763 57899888


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      .+.......+++++++.|+.. .+.|+..+........ ........+...+...           .    ...+....|
T Consensus       186 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~----~~~~~~~~f  249 (376)
T 3HSY_B          186 DCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGANVSGFQIV-----------D----YDDSLVSKF  249 (376)
T ss_dssp             CSCGGGHHHHHHHHHHHSSSGGGCEEEECSSBGGGSCC-CTTTTTTCEEEEEESS-----------C----TTSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHhCCCcCCeEEEEecCCCCcccH-HHhccCCeeEEEEEEe-----------c----CCChHHHHH
Confidence            877777888999998888753 3456655321111000 0000001111111000           0    001111223


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG----YIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~----~~~~~~~~-  434 (908)
                      .+.+++.+.....          ..         ....+..++..+|||++++++|++++....+..    ....|... 
T Consensus       250 ~~~~~~~~~~~~~----------~~---------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~c~~~~  310 (376)
T 3HSY_B          250 IERWSTLEEKEYP----------GA---------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANP  310 (376)
T ss_dssp             HHHHTTSCTTTST----------TC---------SSSCCCHHHHHHHHHHHHHHHHHTTSCCCCCCCCCCCCTTHHHHSC
T ss_pred             HHHHHccChhhCC----------CC---------CCCCCChHHHHHHHHHHHHHHHHHHHHhcccccccCCCCCccCCCC
Confidence            3333322211000          00         001234567889999999999999876432110    00122110 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                        ...++..+.+.|++..|.|.+| ++.|+++|++.. .+.+++++    .+.++.+|.|....
T Consensus       311 ~~~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~  369 (376)
T 3HSY_B          311 AVPWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEVD  369 (376)
T ss_dssp             CCCHHHHHHHHHHHHTCCEEETTE-EECBCTTSCBCSCEEEEEEEE----TTEEEEEEEEETTT
T ss_pred             CCCchhhHHHHHHHhcCCcccCCe-eEEECCCCceeeeEEEEEEee----cCCcEEEEEEeCCC
Confidence              0124556778888889999988 899999898875 88888887    25688999998653


No 81
>3SAJ_B Glutamate receptor 1; Rossmann fold, ion channel, membrane; HET: MAN, BMA, NAG; 2.5A {Rattus norvegicus}
Probab=99.53  E-value=6.5e-19  Score=189.48  Aligned_cols=357  Identities=17%  Similarity=0.268  Sum_probs=217.5  Template_Neff=11.900

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||+++|.++                .....|+++|++++|+++++++++++ +...|+..        ..+.+
T Consensus         6 ~~~~~i~ig~~~p~~~----------------~~~~~~~~~a~~~~n~~~~~~~~~~~-~~~~d~~~--------~~~~~   60 (384)
T 3SAJ_B            6 AMPNNIQIGGLFPNQQ----------------SQEHAAFRFALSQLTEPPKLLPQIDI-VNISDSFE--------MTYRF   60 (384)
T ss_dssp             CCCSEEEEEEEESSSS----------------CHHHHHHHHHHHTCCSSSEEEEEEEE-CCTTCHHH--------HHHHH
T ss_pred             CCCCceeEEEEeCCCC----------------hHHHHHHHHHHHHccCCCccCCccEE-ecCCcHHH--------HHHHH
Confidence            4567899999999875                24668999999999987766655555 44444321        11122


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      .+++.                   ++++++||+.++..+..++..+...++|+|++.+....     ..++++. .+++ 
T Consensus        61 ~~~~~-------------------~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~-----~~~~~~~-~~~~-  114 (384)
T 3SAJ_B           61 CSQFS-------------------KGVYAIFGFYERRTVNMLTSFCGALHVCFITPSFPVDT-----SNQFVLQ-LRPE-  114 (384)
T ss_dssp             HHHHH-------------------HTCSCEEECCCTTTHHHHHHHHHHHTCCEEECSCCCSS-----CCTTEEE-CSCC-
T ss_pred             HHhhh-------------------cCeEEEEecCCHHHHHHHHHHHhhcCCcEEeCCCCCCC-----CCceEEE-echh-
Confidence            22221                   47889999888877777788889999999998754321     1233333 3333 


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                       .+.++++++++++|++|++++ ++.++....+.+++.+++. ++++.....++  .+..++...+++++. .++|+|++
T Consensus       115 -~~~~~~~~~~~~~~~~v~vi~-~~~~~~~~~~~~~~~~~~~-~~~v~~~~~~~--~~~~~~~~~~~~~~~-~~~~~iv~  188 (384)
T 3SAJ_B          115 -LQEALISIIDHYKWQTFVYIY-DADRGLSVLQRVLDTAAEK-NWQVTAVNILT--TTEEGYRMLFQDLEK-KKERLVVV  188 (384)
T ss_dssp             -CHHHHHHHHHHHTCCEEEEEE-CHHHHTTHHHHHHHHHHHH-TCEEEEEETTT--CCHHHHHHHHHHHHH-SSSCEEEE
T ss_pred             -HHHHHHHHHHHcCCCEEEEEE-cCccchHHHHHHHHHHHhc-CCceEEEEecc--CCccchHHHHHHHhh-cCCcEEEE
Confidence             678888888888999999999 6677877788888877765 35554433232  122355666777763 57899888


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSD-SWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVW  358 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~-~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  358 (908)
                      .........+++++++.|+.. .+.|+..+ .|.....  ........+......          + .    ...+....
T Consensus       189 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~~~~~~----------~-~----~~~~~~~~  251 (384)
T 3SAJ_B          189 DCESERLNAILGQIVKLEKNGIGYHYILANLGFMDIDL--NKFKESGANVTGFQL----------V-N----YTDTIPAR  251 (384)
T ss_dssp             ECCHHHHHHHHHHHHHTTCSSTTCEEEEECSBTTSSCC--SSSTTTSCEEEEEEC----------C-C----TTSHHHHH
T ss_pred             ECCHHHHHHHHHHHHHhccccCCeEEEEeeCCccccCH--HHHhccCCceEEEEE----------E-c----CCCchHHH
Confidence            877777788999998888753 46677654 2322110  000000111111000          0 0    00111222


Q NP_000836.2     359 FAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG----YIGLCPRM  434 (908)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~----~~~~~~~~  434 (908)
                      +.+.|++.+..             .|....      ...+..++..+|||++++++++++.....+..    ....|...
T Consensus       252 f~~~~~~~~~~-------------~~~~~~------~~~~~~~~~~~ydav~~~~~al~~~~~~~~~~~~~~~~~~c~~~  312 (384)
T 3SAJ_B          252 IMQQWRTSDSR-------------DHTRVD------WKRPKYTSALTYDGVKVMAEAFQSLRRQRIDISRRGNAGDCLAN  312 (384)
T ss_dssp             HHHHHHHHHHH-------------C------------CCCCHHHHHHHHHHHHHHHHHHHHHHHTCCCCCCCSCCCSCCB
T ss_pred             HHHHHHccCcc-------------CCCCCC------CCCCcchHHHHHHHHHHHHHHHHHHHHCCCCchhcCCCCCcccC
Confidence            33333333221             010000      01234567789999999999999887543210    01122211


Q NP_000836.2     435 ---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       435 ---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                         ...++..+.+.|++..|.|.+| ++.||++|++.. .+.+++++    ++.++.||.|+...
T Consensus       313 ~~~~~~~~~~l~~~l~~~~f~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~  372 (384)
T 3SAJ_B          313 PAVPWGQGIDIQRALQQVRFEGLTG-NVQFNEKGRRTNYTLHVIEMK----HDGIRKIGYWNEDD  372 (384)
T ss_dssp             SCCCCTTHHHHHHHHHTCEEEETTE-EEEBCTTSBBCSCCEEEEEEE----TTEEEEEEEEETTT
T ss_pred             CCCCcccHHHHHHHHhcCCccCCcc-eEEECCCCCeeeeEEEEEEee----eCceEEeEEEcCCC
Confidence               0114456778888888999988 899999888753 56666665    35789999998653


No 82
>3N6V_D Glutamate receptor 2; AMPA, assembly, NTD, GluR2, GluA2; 3.2A {Rattus norvegicus}
Probab=99.52  E-value=6.9e-19  Score=188.37  Aligned_cols=355  Identities=15%  Similarity=0.178  Sum_probs=216.7  Template_Neff=12.200

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI-LDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~-~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      ++||+++|.++.                ....|+++|++++|+.     |.++++.+ .|+.+++..    ..+.+++++
T Consensus         1 i~ig~~~~~~g~----------------~~~~~~~~a~~~in~~-----g~~l~~~~~~~~~~~~~~----~~~~~~~l~   55 (374)
T 3N6V_D            1 IQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSFA----VTNAFCSQF   55 (374)
T ss_dssp             CEEEEEEETTCH----------------HHHHHHHHHHHHHCCS-----SCCCEEEEEEECTTCHHH----HHHHHHHHH
T ss_pred             CceeeeeCCCCH----------------HHHHHHHHHHHHhhCC-----CceeceeEEecCCCChHH----HHHHHHHHH
Confidence            578999988752                4678999999999975     35667665 455444332    222333333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   ++++++||+.++.....++.++...+||+|++.....     ..+++++++.|+   .+.
T Consensus        56 ~-------------------~~v~~iig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~---~~~  108 (374)
T 3N6V_D           56 S-------------------RGVYAIFGFYDKKSVNAITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPD---LKG  108 (374)
T ss_dssp             H-------------------HTCSEEEECCCTTTHHHHHHHHHHHTCEEEECSCCCS-----SCCSSEEECSCC---HHH
T ss_pred             h-------------------cCeeEEEecCChHHHHHHHHHHHhcCCceeeCCCCCC-----CCCCcEEEecCC---HHH
Confidence            2                   4788999998887777778889999999998764321     246889999887   367


Q NP_000836.2     205 AMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE--PRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       205 ~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~--~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      ++++++.+++|+++++++.++ ++....+.+.+.+++. ++++......+..  .+..++...+++++. .++++|++.+
T Consensus       109 ~~~~~~~~~~~~~v~iv~~~~-~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vv~~~  185 (374)
T 3N6V_D          109 ALLSLIEYYQWDKFAYLYDSD-RGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKERRVILDC  185 (374)
T ss_dssp             HHHHHHHHTTCCEEEEEECGG-GCSHHHHHHHHHHHHT-TCEEEEEECTTCCSTTHHHHHHTTSTTTTT-TTCCEEEEES
T ss_pred             HHHHHHHHhCCcEEEEEEeCC-cchhhHHHHHHHHHhc-CCeEEEEEeccCCCCCCccchHHHHHHHcc-cCCcEEEEEC
Confidence            778888788999999999655 7777777777777664 3555432221100  112356666777763 5789988887


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAE  361 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  361 (908)
                      ....+..+++++++.|+.. .+.|+..+........ ........+...+...           .    ...+....|.+
T Consensus       186 ~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~----~~~~~~~~f~~  249 (374)
T 3N6V_D          186 ERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGANVSGFQIV-----------D----YDDSLVSKFIE  249 (374)
T ss_dssp             CHHHHHHHHHHHHHTTCSSTTCEEEECSSBSSSSCC-GGGTTTSCEEEEEESS-----------C----TTSHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHcCCccCceEEEEecCCCCcccH-hHhhcCCeeEEEEEEE-----------c----CCChHHHHHHH
Confidence            7777888999998888753 3456655321111000 0000011111111100           0    00111122333


Q NP_000836.2     362 FWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG----YIGLCPRM---  434 (908)
Q Consensus       362 ~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~----~~~~~~~~---  434 (908)
                      .|++.+.....             ..      ....+..++..+||+++++++|++++....+..    ....|...   
T Consensus       250 ~~~~~~~~~~~-------------~~------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~c~~~~~~  310 (374)
T 3N6V_D          250 RWSTLEEKEYP-------------GA------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAV  310 (374)
T ss_dssp             HHTTSCTTTST-------------TC------SSSCCCHHHHHHHHHHHHHHHHHHTTTTTTCCCCC----CCTTCSSCC
T ss_pred             HHHcCChhhCC-------------CC------CCCccchhHHHHHHHHHHHHHHHHHHHhcccccccCCCCCCccCCCCC
Confidence            33322211000             00      001234567789999999999999886432110    00122110   


Q NP_000836.2     435 STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       435 ~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                      ...++..+.+.|++..|.|.+| ++.|+++|++.. .+.+++++    .+.++.+|.|+...
T Consensus       311 ~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~  367 (374)
T 3N6V_D          311 PWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEVD  367 (374)
T ss_dssp             CCTTHHHHHHHHHTCEEEETTE-EEEBCTTSCBCSCEEEEEEEC----SSCEEEEEEEETTT
T ss_pred             CccchHHHHHHHhcCccccCCe-eEEECCCCCeeeeEEEEEEee----cCCcEEEEEEeCCC
Confidence            0124556778888888999988 899999998875 78888887    24788999998653


No 83
>4GNR_A ABC transporter substrate-binding protein-branched chain; amino acid-binding protein, surface-exposed protein; 1.0A {Streptococcus pneumoniae}
Probab=99.52  E-value=7e-19  Score=186.67  Aligned_cols=347  Identities=15%  Similarity=0.192  Sum_probs=213.1  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||+++|.++...          ..+.....+++.|++++|+.+++ .++++++...|+.+++..    ..+.+
T Consensus         3 ~~~~~~~Ig~~~~~~~~~~----------~~~~~~~~~~~~a~~~~n~~~~~-~~~~~~~~~~d~~~~~~~----~~~~~   67 (353)
T 4GNR_A            3 VEEKTIKIGFNFEESGSLA----------AYGTAEQKGAQLAVDEINAAGGI-DGKQIEVVDKDNKSETAE----AASVT   67 (353)
T ss_dssp             ---CEEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHHTTCB-TTBEEEEEEEECTTCHHH----HHHHH
T ss_pred             ccCceEEEEEEecCCCCch----------HHcHHHHHHHHHHHHHHHHCCCC-CCcceEEEEecCCCChHH----HHHHH
Confidence            3457899999999876421          35667888999999999987654 357788877777655432    33333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                  .++++++||+.++.....+...+...++|+|.+....+.+..  ..++++++.++..
T Consensus        68 ~~l~~------------------~~~v~~iig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~  127 (353)
T 4GNR_A           68 TNLVT------------------QSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTK--GQDYLFIGTFQDS  127 (353)
T ss_dssp             HHHHH------------------TSCCSEEECCCSHHHHHHHHHHHHHTTCCEEESSCCCTTTTT--TCTTEEECSCCHH
T ss_pred             HHHHh------------------cCCeeEEECCCChHHHHHHHHHHHHhCCCEEecCCCCCcCcC--CCCceeEecCChH
Confidence            33332                  147899998877766667777888899999998765544332  2467788888888


Q NP_000836.2     201 YQAQAMVDIVT-ALGWNYVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       201 ~~~~~~~~~l~-~~~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ..++++++++. +++|+++++++.+ +.++....+.+.+...    ..+.....+.  .+..+....++++++ .+++++
T Consensus       128 ~~~~~~~~~l~~~~~~~~v~i~~~~~~~~~~~~~~~~~~~~~----~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i  200 (353)
T 4GNR_A          128 FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYK----GEIVADETFV--AGDTDFQAALTKMKG-KDFDAI  200 (353)
T ss_dssp             HHHHHHHHHHHHTSCCSEEEEEEETTCHHHHHHHHHHHHHCC----SEEEEEEEEC--TTCCCCHHHHHHHHT-SCCSEE
T ss_pred             HHHHHHHHHHHHHcCCCEEEEEEcCcchHHHHHHHHHHHHcC----CceeeEEEec--CCCCCHHHHHHHhhc-CCCCEE
Confidence            88888898885 5789999998855 4555555555554322    2222211121  122345566777763 578888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVW  358 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  358 (908)
                      ++......+..+++++++.|+.  ..|++.+.+...............+.+......          ..  ....+....
T Consensus       201 i~~~~~~~~~~~~~~~~~~g~~--~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------~~--~~~~~~~~~  266 (353)
T 4GNR_A          201 VVPGYYNEAGKIVNQARGMGID--KPIVGGDGFNGEEFVQQATAEKASNIYFISGFS----------TT--VEVSAKAKA  266 (353)
T ss_dssp             ECCSCHHHHHHHHHHHHHTTCC--SCEEECGGGCSHHHHHHHCTTTCCSEEEEESCC----------SS--SSCCHHHHH
T ss_pred             EEcCCHHHHHHHHHHHHHCCCC--CCEEeccccccHHHHHHhchhhhcCEEEEeccc----------CC--cccCHHHHH
Confidence            7776666778888888888773  456665543321110000001111211111000          00  000011112


Q NP_000836.2     359 FAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTID  438 (908)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~  438 (908)
                      |.+.+.+.++                           ..++.++..+||+++++++++++...                 
T Consensus       267 f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~-----------------  302 (353)
T 4GNR_A          267 FLDAYRAKYN---------------------------EEPSTFAALAYDSVHLVANAAKGAKN-----------------  302 (353)
T ss_dssp             HHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHTTCSS-----------------
T ss_pred             HHHHHHHHHC---------------------------CCCChHHHHHHHHHHHHHHHHhcCCC-----------------
Confidence            2222222111                           11235678899999999999987531                 


Q NP_000836.2     439 GKELLGYIRA-VNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       439 ~~~l~~~l~~-~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      ++.+.+.|++ ..|.|.+| ++.|+++|++...+.+.+++    ++.++.+|.|+
T Consensus       303 ~~~~~~~l~~~~~~~g~~G-~~~f~~~~~~~~~~~v~~~~----~~~~~~~~~~~  352 (353)
T 4GNR_A          303 SGEIKDNLAKTKDFEGVTG-QTSFDADHNTVKTAYMMTMN----NGKVEAAEVVK  352 (353)
T ss_dssp             HHHHHHHHHTCCCEEETTE-EECCCTTSCCCCCEEEEEEE----TTEEEEEEEEC
T ss_pred             hHHHHHHHhcCCCCCCCcc-eeEEcCCCCccceEEEEEEE----CCEEEEeeeeC
Confidence            2346677766 47889988 89999988887778888776    35788888885


No 84
>3N0X_A Possible substrate binding protein of; Receptor family ligand binding region; HET: GOL; 1.5A {Rhodopseudomonas palustris}
Probab=99.52  E-value=7.4e-19  Score=188.33  Aligned_cols=348  Identities=14%  Similarity=0.174  Sum_probs=214.4  Template_Neff=11.600

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.++...          ..+.....|++.|++++|+.++.++|.++++.+.|+++++..+    .+.+++
T Consensus         2 ~~~i~Ig~~~~~~g~~~----------~~~~~~~~g~~~a~~~~n~~g~~~~g~~i~~~~~d~~~~~~~~----~~~~~~   67 (374)
T 3N0X_A            2 ADDLKIALIYGKTGPLE----------AYAKQTETGLMMGLEYATKGTMTLDGRKIVVITKDDQSKPDLS----KAALAE   67 (374)
T ss_dssp             --CEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHTTTCCEETTEEEEEEEEECTTCHHHH----HHHHHH
T ss_pred             CCceEEEEEeCCCCCch----------HHHHHHHHHHHHHHHHhhcCCCccCCeEEEEEEecCCCChHHH----HHHHHH
Confidence            46799999999887431          3566788999999999998554355788999988887765433    333344


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.+                  +++++++|+.++.....++..+...++|++...+.++.+.+...+++++++.++....
T Consensus        68 l~~~------------------~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~  129 (374)
T 3N0X_A           68 AYQD------------------DGADIAIGTSSSAAALADLPVAEENKKILIVEPAVADQITGEKWNRYIFRTGRNSSQD  129 (374)
T ss_dssp             HHHT------------------SCCSEEEECSSHHHHHHHHHHHHHHTCCEEECSCCCGGGGTTTCCTTEEECSCCHHHH
T ss_pred             HHhh------------------cCCCEEEecCCcHHHHhHHHHHHHcCCEEEeCCCCchHHhCCCCCccEEEccCCchhH
Confidence            3321                  5788999988777777788888889999998776555443322467889999988888


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET----PNARAV  278 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~----~~~~vi  278 (908)
                      +.++++++.+ .|++|++++.++.++....+.+++.+++. ++++.....+.  .+..++...+++++..    .++++|
T Consensus       130 ~~~~~~~~~~-~~~~v~iv~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~i~~~~~~~~~~~~v  205 (374)
T 3N0X_A          130 AISNAVAIGK-QGVTIATLAQDYAFGRDGVAAFKEALAKT-GATLATEEYVP--TTTTDFTAVGQRLFDALKDKPGKKII  205 (374)
T ss_dssp             HHHHHHHHCC-TTEEEEEEEESSHHHHHHHHHHHHHHTTT-TCEEEEEEEEC--TTCCCCHHHHHHHHHHHTTCSSEEEE
T ss_pred             HHHHHHHHHh-cCCEEEEEecCcHHHHHHHHHHHHHHHHc-CCeeceeeecC--CCCCChHHHHHHHHHHhcCCCCCCeE
Confidence            8888887765 67899999977778888888888888765 45654433332  2233455566666521    145666


Q NP_000836.2     279 IMFA-NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       279 v~~~-~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      ++.. .......++++++..++.  ..|+..+.+....   ... ....+........         ..   ....+...
T Consensus       206 ~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~---~~~-~~~~~~~~~~~~~---------~~---~~~~~~~~  267 (374)
T 3N0X_A          206 WVIWAGGGDPLTKLQDMDPKRYG--IELSTGGNILPAL---AAY-KRLPGMEGATYYY---------YD---IPKNPINE  267 (374)
T ss_dssp             EECCCSSSCHHHHHHHTCGGGGT--EEEEECCCCTTGG---GGG-GGSTTCEEEESCC---------TT---SCCSHHHH
T ss_pred             EEEEecCCcHHHHHHhccccccC--ceeccccchHHHH---HHH-hhCCCceeeeecc---------cc---CCCChhhH
Confidence            5533 344455666666665542  2344332221100   000 0011111100000         00   00011122


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTI  437 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~  437 (908)
                      .|.+.+++.++                           ..++.++..+|||+++++.|++++..               .
T Consensus       268 ~f~~~~~~~~~---------------------------~~p~~~~~~~yda~~~~~~al~~~~~---------------~  305 (374)
T 3N0X_A          268 WLVTEHQKRFN---------------------------APPDFFTAGGFSAAMAVVTAVQKAKS---------------T  305 (374)
T ss_dssp             HHHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHTS---------------C
T ss_pred             HHHHHHHHHHC---------------------------CCCChhHHHHHHHHHHHHHHHHHcCC---------------C
Confidence            23332322221                           11235678899999999999988642               1


Q NP_000836.2     438 DGKELLGYIRAVNFNGSAGTPVTFNE-NGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       438 ~~~~l~~~l~~~~f~G~~G~~v~Fd~-~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ++..+.++|++..|+|.+| ++.|++ ++++...+.+++++..   +    +|.|+..
T Consensus       306 ~~~~i~~~l~~~~~~g~~G-~i~f~~~~~~~~~~~~i~~~~~~---~----~~~w~~~  355 (374)
T 3N0X_A          306 DTEKLIAAMEGMEFDTPKG-KMVFRKEDHQALQSMYHFKVKVD---P----AVAWAVL  355 (374)
T ss_dssp             CHHHHHHHHTTCEEEETTE-EEEECTTTCBEECCEEEEEEECC---T----TSSSCEE
T ss_pred             CHHHHHHHHcCCceecCCe-eEEeCCCCCeeeeeeEEEEEcCC---h----hhhcccc
Confidence            3456778888888999888 899987 5555567777776621   1    5677654


No 85
>6KSP_B Glutamate receptor ionotropic, delta-1; complex, membrane protein; 8.1A {Rattus norvegicus}
Probab=99.52  E-value=7.5e-19  Score=210.74  Aligned_cols=372  Identities=15%  Similarity=0.185  Sum_probs=225.3  Template_Neff=11.500

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILD-TCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d-~~~~~~~a~~~~~~~~~~  122 (908)
                      ++++||+++|.++.                ....|+++|++++|+++++++|+++++++.| +++++..+    .+.+++
T Consensus         2 ~~i~Ig~l~p~sg~----------------~~~~g~~~a~~~in~~~g~~~~~~i~~~~~d~~~~~~~~~----~~~~~~   61 (856)
T 6KSP_B            2 SIIHIGAIFEENAA----------------KDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQA----VQEACD   61 (856)
T ss_dssp             CCCBCCEEECSCCH----------------HHHHHHHHHHHHHHSSCSSSTTCCCBCCEEECCSSCCHHH----HHHHHH
T ss_pred             ceeeeeeeeccccc----------------CchHHHHHHHHHHhcCcccccccceeEEeEeccCCCHHHH----HHHHHH
Confidence            57999999998752                5678999999999998877767899999888 55554332    233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS--  200 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~--  200 (908)
                      ++.                   ++++++||+.++..+.+++..+...++|+|++ +..+.+..  .++++++..+++.  
T Consensus        62 l~~-------------------~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~-~~~~~~~~--~~~~~~~~~~~~~~~  119 (856)
T 6KSP_B           62 LMT-------------------QGILALVTSTGCASANALQSLTDAMHIPHLFV-QRNPGGSP--RTACHLNPSPDGEAY  119 (856)
T ss_dssp             HTT-------------------TCCSCCCCBCCSTTSHHHHHHHHTTTCCEEEC-CCCTTSCC--CCCCCCCSCCTTTCC
T ss_pred             Hhh-------------------cCeeEEecCCCchhHHHHHHHHHhcCCCEEEe-ecCCCCCC--CcccccccCCCCCce
Confidence            332                   57899999988887778888899999999998 44443332  3455666655554  


Q NP_000836.2     201 --------YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPR---E---PRPGEFEKII  266 (908)
Q Consensus       201 --------~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~---~---~~~~~~~~~~  266 (908)
                              .++.++++++++++|+++++++ +++++....+.+.+.+++. ++++.....++.   +   ....+....+
T Consensus       120 ~~~~~p~~~~~~~l~~~~~~~~~~~v~il~-~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~~~l  197 (856)
T 6KSP_B          120 TLASRPPVRLNDVMLRLVTELRWQKFVMFY-DSEYDIRGLQSFLDQASRL-GLDVSLQKVDKNISHVFTSLFTTMKTEEL  197 (856)
T ss_dssp             EEECSCCCCHHHHHHHHHHHHTCCSCEEEE-CTTCCGGGGTTHHHHHHHT-TCCCEEEECCSCHHHHHHHHHHHCCHHHH
T ss_pred             eeecCCCccHHHHHHHHHHHcCCcEEEEEE-eCCchHHHHHHHHHHHHhh-CCeEEEEEccCChhHhcHHHHhhhcHHHH
Confidence                    7788888888888999999999 6667777777777777664 355433222110   0   0122334556


Q NP_000836.2     267 KRLLETPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYF  345 (908)
Q Consensus       267 ~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~  345 (908)
                      +++++ . .+.+++.+....+..+++++++.|+.. .+.|+..+.+...............+.......           
T Consensus       198 ~~~~~-~-~~~vv~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~-----------  264 (856)
T 6KSP_B          198 NRYRD-T-LRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQI-----------  264 (856)
T ss_dssp             HHHHH-H-HTEEEECSCHHHHHHHHHHHHHTTCCCTTCEEEECCSCCCHHHHHHHHHHCSSBCEEEECC-----------
T ss_pred             Hhchh-h-cceEEEEcChHHHHHHHHHHHHcCCCCCCceEEEEcCCCCChhHHHHHhhhcccceEEehh-----------
Confidence            66653 3 344444455667888899998888753 356666543322111000000011111111000           


Q NP_000836.2     346 RSRTLANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP  425 (908)
Q Consensus       346 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~  425 (908)
                      .    ...+....|.+.+++.+.+.             |.....    ....+..++..+|||++++++|++++....+.
T Consensus       265 ~----~~~~~~~~f~~~~~~~~~~~-------------~~~~~~----~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~  323 (856)
T 6KSP_B          265 F----PSAKDNQKCMRNNHRISSLL-------------CDPQEG----YLQMLQISNLYLYDSVLMLANAFHRKLEDRKW  323 (856)
T ss_dssp             C----CCSCCSSTTBCSSCBCCSST-------------TTTCTT----TSTTCCHHHHHHHHHHHHHHHHHHHHHTTTCC
T ss_pred             c----CCcchhHHHHhhcccccccc-------------cCCCcc----ccccccHHHHHHHHHHHHHHHHHHHHHHcCCc
Confidence            0    00111222333333332210             000000    00123456788999999999999987643211


Q NP_000836.2     426 G--YIGLCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITN-KSTEYKVIGHWTNQ  494 (908)
Q Consensus       426 ~--~~~~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~-~~~~~~~Vg~~~~~  494 (908)
                      .  ....|...   ...++..+.++|++..|.|.+| ++.||++|++. ..+.+++++..+ ....+..||.|...
T Consensus       324 ~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~g~~G-~v~f~~~g~~~~~~~~i~~~~~~~~~~~~~~~v~~~~~~  398 (856)
T 6KSP_B          324 HSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTG-VMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSE  398 (856)
T ss_dssp             CCCCSCCSSSSCCCCCSTTHHHHHHHHTCCCCSSSS-CCCCCTTCBCCCCEEEEEECCCBTTTBCCCCCCEEEETT
T ss_pred             ccccccccccCCCCCccCchhHHHHHHhCceeeeee-eEEecCCCCCceEEEEEEeeccCCcCCcceEEEEEEeCC
Confidence            0  01112110   1124567888888889999998 89999999875 578888887431 12367889999864


No 86
>3N6V_B Glutamate receptor 2; AMPA, assembly, NTD, GluR2, GluA2; 3.2A {Rattus norvegicus}
Probab=99.52  E-value=8.3e-19  Score=187.76  Aligned_cols=355  Identities=15%  Similarity=0.178  Sum_probs=216.6  Template_Neff=12.200

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRI-LDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~-~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      ++||+++|.++.                ....|+++|++++|+.     |.++++.+ .|+.+++..    ..+.+++++
T Consensus         1 i~ig~~~~~~g~----------------~~~~~~~~a~~~in~~-----g~~l~~~~~~~~~~~~~~----~~~~~~~l~   55 (374)
T 3N6V_B            1 IQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSFA----VTNAFCSQF   55 (374)
T ss_pred             CeEEEEccCCCH----------------HHHHHHHHHHHHHHHC-----CCEEEEEEEeCCCCCHHH----HHHHHHHHH
Confidence            578999988752                4678999999999975     35667665 455444332    222333333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   ++++++||+.++.....++.++...+||+|++.....     ..+++++++.|+   .+.
T Consensus        56 ~-------------------~~v~~iig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~---~~~  108 (374)
T 3N6V_B           56 S-------------------RGVYAIFGFYDKKSVNAITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPD---LKG  108 (374)
T ss_pred             h-------------------cCCCEEECCCChHHHHHHHHHHHhhCCCEECCCcCCC-----ccCCceeecCHH---HHH
Confidence            2                   4788999998887777778888999999998764321     246889999887   367


Q NP_000836.2     205 AMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPRE--PRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       205 ~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~--~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      ++++++.+++|++++++++++ ++....+.+.+.+++. ++++......+..  .+..++...+++++. .++++|++.+
T Consensus       109 ~~~~~~~~~~~~~v~iv~~~~-~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vv~~~  185 (374)
T 3N6V_B          109 ALLSLIEYYQWDKFAYLYDSD-RGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKERRVILDC  185 (374)
T ss_pred             HHHHHHHHhCCCeEEEEEeCc-hhHHHHHHHHHHHHHC-CCEEEEEEeeCCCCCCCCCCHHHHHHHHHH-cCCCEEEEeC
Confidence            778888788999999999655 7777777777777664 3555432221100  122356666777763 5789988887


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAE  361 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  361 (908)
                      ....+..+++++++.|+.. .+.|+..+........ ........+...+...           .    ...+....|.+
T Consensus       186 ~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~-----------~----~~~~~~~~f~~  249 (374)
T 3N6V_B          186 ERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGANVSGFQIV-----------D----YDDSLVSKFIE  249 (374)
T ss_pred             CHHHHHHHHHHHHHcCCCCCCcEEEEecCCCCCCch-HHhhccccceeeeeec-----------C----CCCHHHHHHHH
Confidence            7777888999998888753 3456655321111000 0000011111111100           0    00111122333


Q NP_000836.2     362 FWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG----YIGLCPRM---  434 (908)
Q Consensus       362 ~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~----~~~~~~~~---  434 (908)
                      .|++.+.....             ..      ....+..++..+||+++++++|++++....+..    ....|...   
T Consensus       250 ~~~~~~~~~~~-------------~~------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~c~~~~~~  310 (374)
T 3N6V_B          250 RWSTLEEKEYP-------------GA------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANPAV  310 (374)
T ss_pred             HHHHHhCCCCC-------------CC------CCCCCccHHHHHHHHHHHHHHHHHHHhhcCCcccCCCCCCccCCCCCC
Confidence            33322211000             00      001234567789999999999999886432110    00122110   


Q NP_000836.2     435 STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQL  495 (908)
Q Consensus       435 ~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~~  495 (908)
                      ...++..+.+.|++..|.|.+| ++.|+++|++.. .+.+++++    .+.++.+|.|....
T Consensus       311 ~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~vg~w~~~~  367 (374)
T 3N6V_B          311 PWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEVD  367 (374)
T ss_pred             CCCCHHHHHHHHHcCcccCCCc-ceEeCCCCCcCCCeEEEEEEe----CCceEEeEEEeCCC
Confidence            0124556778888889999988 899999998875 78888887    24788999998653


No 87
>1Z17_A Leu/Ile/Val-binding protein; periplasmic binding proteins, alpha-beta fold; 1.96A {Escherichia coli}
Probab=99.52  E-value=8.4e-19  Score=185.21  Aligned_cols=333  Identities=20%  Similarity=0.234  Sum_probs=211.1  Template_Neff=12.300

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|.++...          ..+.....+++.|++++|+.+++. |+++++.+.|+.+++.    ...+.+++++
T Consensus         2 ~~~Ig~~~~~~~~~~----------~~~~~~~~~~~~a~~~~n~~~~~~-g~~i~~~~~d~~~~~~----~~~~~~~~l~   66 (344)
T 1Z17_A            2 DIKVAVVGAMSGPVA----------QYGDQEFTGAEQAVADINAKGGIK-GNKLQIVKYDDACDPK----QAVAVANKVV   66 (344)
T ss_dssp             CEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHHHHTTTBT-TBCEEEEEEECTTCHH----HHHHHHHHHH
T ss_pred             CeEEEEEecCCCchH----------HhhHHHHHHHHHHHHHHHHCCCcC-CceEEEEEEcCCCCHH----HHHHHHHHHH
Confidence            689999999875321          245678899999999999876543 6778888777665532    2223333333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   ++++++|++.++.....+...+...++|+|.+....+.+... .+++++++.+++...+.
T Consensus        67 ~-------------------~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~  126 (344)
T 1Z17_A           67 N-------------------DGIKYVIGHLCSSSTQPASDIYEDEGILMITPAATAPELTAR-GYQLILRTTGLDSDQGP  126 (344)
T ss_dssp             H-------------------TTCCEEEECCSHHHHHHHHHHHHHHTCEEEESSCCCGGGGSS-CCSSEEESSCCHHHHHH
T ss_pred             h-------------------cCCCEEEcCCCCcchHHHHHHHHHHCCeEEecCCCCHHHHhc-CCCeEEEecCCcccchH
Confidence            2                   478899988766655566677788899999987655443221 24677888888888888


Q NP_000836.2     205 AMVDIVT-ALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFAN  283 (908)
Q Consensus       205 ~~~~~l~-~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~~  283 (908)
                      .+++++. +.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .+++++++...
T Consensus       127 ~~~~~l~~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~~~~  202 (344)
T 1Z17_A          127 TAAKYILEKVKPQRIAIVHDKQQYGEGLARAVQDGLKKG-NANVVFFDGIT--AGEKDFSTLVARLKK-ENIDFVYYGGY  202 (344)
T ss_dssp             HHHHHCCCCCCCSSEEEEECSSHHHHHHHHHHHHHHHHT-TCCEEEEEECC--TTCCCCHHHHHHHHH-TTCCEEEEESC
T ss_pred             HHHHHHHHHcCCCEEEEEEcCCchhHHHHHHHHHHHHhC-CCEEeEEeccC--CCCCChHHHHHHHHH-CCCCEEEEecC
Confidence            8888884 4589999999976667777788888887765 35543322222  122345556666653 47888877765


Q NP_000836.2     284 EDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFW  363 (908)
Q Consensus       284 ~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  363 (908)
                      +..+..+++++++.|+  ++.|++.+.+...... ........+.+...+..              ....+....|.+.+
T Consensus       203 ~~~~~~~~~~~~~~g~--~~~~i~~~~~~~~~~~-~~~~~~~~g~~~~~~~~--------------~~~~~~~~~f~~~~  265 (344)
T 1Z17_A          203 HPEMGQILRQARAAGL--KTQFMGPEGVANVSLS-NIAGESAEGLLVTKPKN--------------YDQVPANKPIVDAI  265 (344)
T ss_dssp             HHHHHHHHHHHHHTTC--CCEEEECGGGCSHHHH-HHHGGGGTTCEEEECCC--------------GGGSGGGHHHHHHH
T ss_pred             chHHHHHHHHHHHcCC--CcEEEcCCcccCHHHH-HHhhhhcCCeEEEcCCC--------------CCCCcchHHHHHHH
Confidence            6667788899888887  3567766543322110 00111122322211100              00001111222222


Q NP_000836.2     364 EENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELL  443 (908)
Q Consensus       364 ~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~l~  443 (908)
                      ++.++                           ..++.++..+|||++++++++++..                 ++..+.
T Consensus       266 ~~~~~---------------------------~~~~~~~~~~yda~~~~~~a~~~~~-----------------~~~~l~  301 (344)
T 1Z17_A          266 KAKKQ---------------------------DPSGAFVWTTYAALQSLQAGLNQSD-----------------DPAEIA  301 (344)
T ss_dssp             HTTTC---------------------------CCCSHHHHHHHHHHHHHHHHHTTCS-----------------CHHHHH
T ss_pred             HHHHC---------------------------CCCChHHHHHHHHHHHHHHHHhcCC-----------------CHHHHH
Confidence            22111                           1123457789999999999987631                 234577


Q NP_000836.2     444 GYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQI  478 (908)
Q Consensus       444 ~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~  478 (908)
                      ++|++..|.|.+| ++.|+++|++. ..+.+.+++.
T Consensus       302 ~~l~~~~~~g~~G-~i~f~~~g~~~~~~~~i~~~~~  336 (344)
T 1Z17_A          302 KYLKANSVDTVMG-PLTWDEKGDLKGFEFGVFDWHA  336 (344)
T ss_dssp             HHHHHSCEEETTE-EECBCTTSCBTTCCCEEEEECT
T ss_pred             HHHHhCCCCcCce-eeEeCCCCCcCcceEEEEEEec
Confidence            7788888999998 89999989876 5777887773


No 88
>4RU0_B Putative branched-chain amino acid ABC; ABC transporter permease, Structural Genomics; HET: MSE, GOL, P3G; 2.442A {Pseudomonas protegens Pf-5}
Probab=99.51  E-value=1e-18  Score=192.27  Aligned_cols=370  Identities=12%  Similarity=0.111  Sum_probs=225.6  Template_Neff=11.600

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINK-DPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~-~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      ....++++||++.|.++...          ..+.....|++.|++++|+ .+++. |+++++.+.|+++++..    ..+
T Consensus        28 ~~~~~~~~ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~~g~~~-g~~v~~~~~d~~~~~~~----~~~   92 (447)
T 4RU0_B           28 QAGPDQQFFPLATYRVGAYA----------SSGVQVWAGMIDYLNYINQVEGGIN-GVKLVWQECETEWTAEK----GIE   92 (447)
T ss_dssp             --CTTSEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHHTTCSBT-TBCEEEEEEECTTCHHH----HHH
T ss_pred             hcCCCceEEEEeeccCCCcc----------ccchhHHHHHHHHHHHHHHhcCCcC-CeEeEEEEEcCCCCHHH----HHH
Confidence            34567899999999875421          2566788999999999997 55443 67788887777655332    333


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+++++.+                ..+.+++++++.++.....+...+...++|+|.+.+..+.+.+....++++++.++
T Consensus        93 ~~~~l~~~----------------~~~~~~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  156 (447)
T 4RU0_B           93 CYERFKNG----------------LDGAPVAVYQPNGAPAAYALSERAEVDKIPLITLGYGRTEATDGTVFPYNFPVMLT  156 (447)
T ss_dssp             HHHHHTTC----------------BTTBCBSCBCCCSHHHHHHHHHHHHHTTCCEECTTCSCGGGGCTTTCTTEECCSCC
T ss_pred             HHHHHHhc----------------CCCCCEEEEcCCCcHHHHHHHHHHHHcCCCEEEcCCCchhhcCCCCCCccccccCC
Confidence            34443320                00367788888777666677778888999999987765543321235678899999


Q NP_000836.2     199 DSYQAQAMVDIVTA-------LGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       199 ~~~~~~~~~~~l~~-------~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      +...++.+++++.+       .+|++|++++.++.++..+.+.+++.+++. ++++... .+.  ....+....+++++.
T Consensus       157 ~~~~~~~~~~~~~~~~~~~~~~~~~~i~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~-~~~--~~~~~~~~~~~~~~~  232 (447)
T 4RU0_B          157 FYSEASTLVNYIAQREGGFDRLKGKKIATLYHDSAYGRETLGPLKLLAEKY-GFENIQI-PVA--DPGNEQSAQWRQIRQ  232 (447)
T ss_dssp             HHHHHHHHHHHHHHHHTSGGGGTTCEEEEEEESSHHHHTTHHHHHHHHHHH-CCEEEEE-EEC--TTCCCCHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHhcCCccccCCCEEEEEecCChHhHhcHHHHHHHHHHh-CCEEEEE-EeC--CCCCchHHHHHHHHH
Confidence            88888899998865       689999999966667777888888888775 4555431 121  122345566666663


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLA  351 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~  351 (908)
                       .++|++++...+..+..+++++++.|+..  .++..+.|...............+.+......          ..   .
T Consensus       233 -~~~~~i~~~~~~~~~~~~~~~~~~~g~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------~~---~  296 (447)
T 4RU0_B          233 -QNPDWVFLRTWGVSTPVAVKTAARFGFPV--DHIIGDIWASSSEDVLPAGAAAKGYLALTPYP----------AG---S  296 (447)
T ss_dssp             -HCCSEEEEECCTTHHHHHHHHHHHTTCCG--GGEEECGGGCSGGGTGGGGGGGTTCEEEESSC----------CC---S
T ss_pred             -hCCCEEEEEcCCccHHHHHHHHHHcCCCC--cEEEeeccCCCchhhHhhHHhhCCeEEeecCC----------CC---C
Confidence             57888887765666778889988888753  23333323221100000111122222211100          00   0


Q NP_000836.2     352 NNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLC  431 (908)
Q Consensus       352 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~  431 (908)
                      ..+....|.+.+++.+...+..                    ....++.++..+|||+++++++++++......      
T Consensus       297 ~~~~~~~f~~~~~~~~~~~~~~--------------------~~~~~~~~~~~~yda~~~~~~al~~~~~~~g~------  350 (447)
T 4RU0_B          297 DFEIHKRLKQYILDTGKSDLKD--------------------LKNFGSVYYNSGLVNAAVAVEAIRTAQGKFGK------  350 (447)
T ss_dssp             CSTTHHHHCCCCCTTTCCSCSC--------------------GGGTTSHHHHHHHHHHHHHHHHHHHHHHHHCS------
T ss_pred             CCHHHHHHHHHHHHhCCCcccc--------------------ccccCChhHHHHHHHHHHHHHHHHHHHHhcCC------
Confidence            0011112222222211100000                    00112456788999999999999987532100      


Q NP_000836.2     432 PRMSTIDGKELLGYIRAVNF----------NGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       432 ~~~~~~~~~~l~~~l~~~~f----------~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                         ...++..+.+.|++..+          .|.+| ++.|+++|++. ..+.+++++    ++.++.++.|...
T Consensus       351 ---~~~~~~~l~~~l~~~~~~~~~~~~~~~~G~~G-~i~f~~~~~~~~~~~~i~~~~----~g~~~~v~~~~~~  416 (447)
T 4RU0_B          351 ---RPLNGEEGRWGLEHLNIDDARLKDMGYLGLMQ-NLKLSCRDHEGGGAARVQQWD----GANWTLISEWIAA  416 (447)
T ss_dssp             ---SCCCHHHHHHHHHTCEECHHHHHHHTCTTTSC-CEECCSSCSCCCCEEEEEEEC----SSCEEECCCCEEC
T ss_pred             ---CCCChHHHHHHHHhccCCchHHhccCcccccc-CeeecCCCCcccceEEEEEEe----CCeEEEcceeEec
Confidence               01245567777777666          67888 89999888764 467788886    3578899988754


No 89
>5EWM_D NMDA glutamate receptor subunit, Glutamate; Glutamate receptor, allosteric modulator, GluN2B; HET: MAN, 5SM, NAG, BMA; 2.76A {Xenopus laevis}
Probab=99.51  E-value=1e-18  Score=186.31  Aligned_cols=349  Identities=15%  Similarity=0.211  Sum_probs=214.9  Template_Neff=11.900

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||+++|.++                  ...|+++|++++|+.++.. +.++++... ++.++..    ..+.+.+
T Consensus         2 ~~~i~Ig~~~~~~~------------------~~~~~~~a~~~in~~~~~~-~~~i~l~~~-~~~~~~~----~~~~~~~   57 (364)
T 5EWM_D            2 PPSIGIAVILVGTS------------------DEVAIKDAHEKDDFHHLSV-VPRVELVAM-NETDPKS----IITRICD   57 (364)
T ss_dssp             CCEEEEEEEEESSC------------------CHHHHHC------CCCSSS-EEEEEEEEE-CCCSHHH----HHHHHHH
T ss_pred             CCeeeEEEEEeCCC------------------chHHHHHHHHhcCCCcCcc-CCceEEEee-CCCCHHH----HHHHHHH
Confidence            46789999998652                  4578999999999875432 455666655 3444322    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVI--GAAASS-VSIMVANILRLFKIPQISYASTAP-ELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vI--g~~~s~-~~~~va~~~~~~~iP~Is~~~~~~-~l~~~~~~~~~~~~~~~  198 (908)
                      ++.                  .+++++++  |+.++. .+..+..++...++|+|++.+..+ .+.+...+++++++.|+
T Consensus        58 l~~------------------~~~v~~vi~~g~~~s~~~~~~~~~~~~~~~iP~i~~~~~~~~~~~~~~~~~~~~~~~~~  119 (364)
T 5EWM_D           58 LMS------------------DRKIQGVVFADDTDQEAIAQILDFISAQTLTPILGIHGGSSMIMADKDESSMFFQFGPS  119 (364)
T ss_dssp             HHH------------------HSCEEEEEEECSSCCTHHHHHHHHHHHHHTCCEEEEEGGGSSCCCSCCTTCCEEESSCC
T ss_pred             HHh------------------cCCceEEEEcCCCChHHHHHHHHHHHHhhCCCEEeecCCCcccccCcccCcceeecCCC
Confidence            332                  14789999  887775 466777788889999999876542 33333357899999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPR-PGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~-~~~~~~~~~~l~~~~~~~v  277 (908)
                      +...++++++++++++|+++++++.++.++....+.+++.+++. ++++.....+..... ..++...+++++. .++++
T Consensus       120 ~~~~~~~~~~~~~~~~~~~i~il~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~i~~-~~~~~  197 (364)
T 5EWM_D          120 IEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFVNKIRSTIENS-FVGWELEEVLLLDMSLDDGDSKIQNQLKK-LQSPI  197 (364)
T ss_dssp             HHHHHHHHHHHHHHHTCCEEEEEEESSTTHHHHHHHHHHHHHSC-CSSCEEEEEEEECCSSCCTTCHHHHHHTT-CCCSE
T ss_pred             HHHHHHHHHHHHHHcCCeEEEEEEEcCCchHHHHHHHHHHHHhh-CCcEEEEEEEecCCCCCcchHHHHHHHHh-CCCCE
Confidence            98889999999988899999999987777777778888877765 355443222210011 2345566666753 57888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      |++.+....+..+++++++.|+.. .+.|+..+.+......  .......+.+.+                     .   
T Consensus       198 v~~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~~~---------------------~---  251 (364)
T 5EWM_D          198 ILLYCTKEEATYIFEVANSVGLTGYGYTWIVPSLVAGDTDT--VPAEFPTGLISV---------------------S---  251 (364)
T ss_dssp             EEEESCHHHHHHHHHHHHHTTCSSTTCEEEECHHHHCSTTC--CCTTSCTTCEEE---------------------E---
T ss_pred             EEEeCCHHHHHHHHHHHHHcCCCCCcEEEEeecCCCCCCCC--CCccCCCcEEEE---------------------e---
Confidence            888877777788899998888753 3566665422111000  000000010000                     0   


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG--YIGLCPRM  434 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~--~~~~~~~~  434 (908)
                        .     ..+                              ...++..+|||++++++|++++....+..  ....|...
T Consensus       252 --~-----~~~------------------------------~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~c~~~  294 (364)
T 5EWM_D          252 --Y-----DEW------------------------------DYGLPARVRDGIAIITTAASDMLSEHSFIPEPKSSCYNT  294 (364)
T ss_dssp             --E-----CTT------------------------------TSCHHHHHHHHHHHHHHHHHHHHHHHSCCCCCCSCSSCS
T ss_pred             --e-----cCc------------------------------ccCccHHHHHHHHHHHHHHHHHHhhCCCCCCCCCccccC
Confidence              0     000                              01235679999999999999886532110  01223211


Q NP_000836.2     435 ---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 ---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                         ...++..+.++|++..|.|  | .+.|+++|++. ..+.|++++.   +..++.||.|+... +....+.|+
T Consensus       295 ~~~~~~~~~~l~~~l~~~~~~g--g-~~~f~~~g~~~~~~~~i~~~~~---~~~~~~vg~w~~~~-l~~~~~~w~  362 (364)
T 5EWM_D          295 HEKRIYQSNMLNRYLINVTFEG--R-DLSFSEDGYQMHPKLVIILLNK---ERKWERVGKWKDKS-LQMKYYVWP  362 (364)
T ss_dssp             GGGGGGCCCTTHHHHTSCCCC-----CCCBCTTSBBSSCCEEEEEECT---TSCEEEEEEECSSC-EEESCSSCC
T ss_pred             ccceeehHHHHHHHheeeEecC--e-eeeeCCCCccccceEEEEEecC---CccEEEeEEEECCe-eeeeceecC
Confidence               1124566778888888988  7 89999999886 5788888873   24688999998762 322345563


No 90
>4MLC_A Extracellular ligand-binding receptor; Structural Genomics, PSI-Biology, Midwest Center; HET: MSE, SO4; 2.705A {Desulfitobacterium hafniense}
Probab=99.51  E-value=1.1e-18  Score=185.42  Aligned_cols=346  Identities=20%  Similarity=0.252  Sum_probs=211.0  Template_Neff=12.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.+.              .+.....+++.|++++|+.+++ .|.++++.+.|+.+++..    ..+.
T Consensus         5 ~~~~~~~~Ig~~~~~~~--------------~~~~~~~~~~~a~~~~n~~~~~-~g~~~~~~~~d~~~~~~~----~~~~   65 (356)
T 4MLC_A            5 VNPSEEIFIGVAWPFAS--------------LDDLFAEGLELAVQEINEQGGV-QGRKLSLVKADDEAELEK----GLAI   65 (356)
T ss_dssp             ----CEEEEEEEECCTT--------------CCSSHHHHHHHHHHHHHTTTTB-TTBEEEEEEEECTTCHHH----HHHH
T ss_pred             cCCCCcEEEEEEcCCCC--------------ccHHHHHHHHHHHHHHHHcCCc-CCeeEEEEEEcCcccHHH----HHHH
Confidence            34567899999999642              3456788999999999987654 367788888887665432    2333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++++.                  .++++++|++.++.....+...+...++|+|++....+.+... .+++++++.+++
T Consensus        66 ~~~l~~------------------~~~v~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~  126 (356)
T 4MLC_A           66 AQAFAD------------------NAGIQAVIGHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDH-GYIHVFRNIPSD  126 (356)
T ss_dssp             HHHHHT------------------CTTEEEEECCSSHHHHHHHHHHHHHHTCEEEESSCCCGGGGSS-CCSSEEESSCCH
T ss_pred             HHHHHH------------------cCCccEEEcCCCchhhHHHHHHHHHhCCeEEEcCcCCcccccC-CCCCeEECCCCH
Confidence            333332                  1478999988776666666777888999999887655443221 356788899988


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      ...++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++++++
T Consensus       127 ~~~~~~~~~~l~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~v~  202 (356)
T 4MLC_A          127 QEIARQLAIYLAEQGHERMVIYYTDDSYGNGLANAFEDYARAQ-GITIVDRFNYY--GNLKDLERLYDKWQA-FGMDGIF  202 (356)
T ss_dssp             HHHHHHHHHHHHHTTCCEEEEEECSSHHHHHHHHHHHHHHHHT-TCEEEEEESCC--CSHHHHHHHHHHHHH-HTCCEEE
T ss_pred             HHHHHHHHHHHHHcCCCEEEEEEcCCcchhHHHHHHHHHHHHC-CCeEeEEEecC--CCCccHHHHHHHHHH-cCCCEEE
Confidence            8888999999888899999999966667777888888888775 45554322221  122345556666653 4778887


Q NP_000836.2     280 MFANE-DDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAP--VYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       280 ~~~~~-~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~--~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      +.... ..+..+++++++.|+.  .+|++.+.|......  .........+.+.....          ...   ...+..
T Consensus       203 ~~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------~~~---~~~~~~  267 (356)
T 4MLC_A          203 IAKTATGGGTEFLVDAKSVGIE--VPLIAGNSWDALSLTEDIENIGMTAEGLLVGSFF----------NPQ---RPDSRT  267 (356)
T ss_dssp             EESCCCCCCHHHHHHHHHHTCC--SCEEECGGGCC----------CGGGTTCEEEEEC----------CTT---CSSHHH
T ss_pred             EEecCccchHHHHHHHHHcCCC--CCEEecCccchhchHHHHHHhhhhhcCeEEEecC----------CCC---CCChhH
Confidence            76543 3567788888887773  456655544321100  00000111121111100          000   000111


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMST  436 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~  436 (908)
                      ..|.+.+++.++                           ..++.++..+|||++++++|+++...               
T Consensus       268 ~~f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~---------------  305 (356)
T 4MLC_A          268 QDFVEAFRREYG---------------------------QPPTSYAAAGYDAVILLAEALEKSDL---------------  305 (356)
T ss_dssp             HHHHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHTTSCS---------------
T ss_pred             HHHHHHHHHHHC---------------------------CCCCHHHHHHHHHHHHHHHHHHhCCC---------------
Confidence            122222222111                           11235677899999999999987642               


Q NP_000836.2     437 IDGKELLGYIRA-VNFNGSAGTPVTFNENGDAPGRYD-IFQYQITNKSTEYKVIG  489 (908)
Q Consensus       437 ~~~~~l~~~l~~-~~f~G~~G~~v~Fd~~G~~~~~~~-i~~~~~~~~~~~~~~Vg  489 (908)
                      .+++.+.+.|++ ..|.|.+| .+.|+++|++...+. +.++.    ++.++.+|
T Consensus       306 ~~~~~~~~~l~~~~~~~g~~G-~~~f~~~g~~~~~~~~~~~~~----~g~~~~~~  355 (356)
T 4MLC_A          306 THPATLAQGLRDLGPWEGVMG-MHRFDGRGDDIGDLVVLKKMK----DGRFEYLG  355 (356)
T ss_dssp             SSTTHHHHHHHHHCSEEETTE-EECBCTTCCBCSSCEEEEEEE----TTEEEEC-
T ss_pred             CCHHHHHHHHHhhCCCCCcce-eEEECCCCCcccceEEEEEEE----CCEEEEcC
Confidence            134457777877 47899988 899999888765433 44443    24555554


No 91
>4Q6B_A Extracellular ligand-binding receptor; Structural Genomics, PSI-Biology, Midwest Center; 1.667A {Desulfitobacterium hafniense}
Probab=99.51  E-value=1.1e-18  Score=185.42  Aligned_cols=346  Identities=20%  Similarity=0.252  Sum_probs=211.0  Template_Neff=12.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.+.              .+.....+++.|++++|+.+++ .|.++++.+.|+.+++..    ..+.
T Consensus         5 ~~~~~~~~Ig~~~~~~~--------------~~~~~~~~~~~a~~~~n~~~~~-~g~~~~~~~~d~~~~~~~----~~~~   65 (356)
T 4Q6B_A            5 VNPSEEIFIGVAWPFAS--------------LDDLFAEGLELAVQEINEQGGV-QGRKLSLVKADDEAELEK----GLAI   65 (356)
T ss_dssp             ----CEEEEEEEECTTT--------------CCSSHHHHHHHHHHHHHHTTCB-TTBEEEEEEEECTTCHHH----HHHH
T ss_pred             cCCCCcEEEEEEcCCCC--------------ccHHHHHHHHHHHHHHHHcCCc-CCeeEEEEEEcCcccHHH----HHHH
Confidence            34567899999999642              3456788999999999987654 367788888887665432    2333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++++.                  .++++++|++.++.....+...+...++|+|++....+.+... .+++++++.+++
T Consensus        66 ~~~l~~------------------~~~v~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~-~~~~~~~~~~~~  126 (356)
T 4Q6B_A           66 AQAFAD------------------NAGIQAVIGHRNSFISIPAASIYDQAGLVMLSPASTSPDLTDH-GYIHVFRNIPSD  126 (356)
T ss_dssp             HHHHHT------------------CTTEEEEECCSSHHHHHHHHHHHHHHTCCEEESSCCCGGGGSS-CCSSEEESSCCH
T ss_pred             HHHHHH------------------cCCccEEEcCCCchhhHHHHHHHHHhCCeEEEcCcCCcccccC-CCCCeEECCCCH
Confidence            333332                  1478999988776666666777888999999887655443221 356788899988


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      ...++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++++++
T Consensus       127 ~~~~~~~~~~l~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~v~  202 (356)
T 4Q6B_A          127 QEIARQLAIYLAEQGHERMVIYYTDDSYGNGLANAFEDYARAQ-GITIVDRFNYY--GNLKDLERLYDKWQA-FGMDGIF  202 (356)
T ss_dssp             HHHHHHHHHHHHHTTCCEEEEEECSSHHHHHHHHHHHHHHHHT-TCEEEEEESCC--CSHHHHHHHHHHHHH-TTCCEEE
T ss_pred             HHHHHHHHHHHHHcCCCEEEEEEcCCcchhHHHHHHHHHHHHC-CCeEeEEEecC--CCCccHHHHHHHHHH-cCCCEEE
Confidence            8888999999888899999999966667777888888888775 45554322221  122345556666653 4778887


Q NP_000836.2     280 MFANE-DDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAP--VYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       280 ~~~~~-~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~--~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      +.... ..+..+++++++.|+.  .+|++.+.|......  .........+.+.....          ...   ...+..
T Consensus       203 ~~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~----------~~~---~~~~~~  267 (356)
T 4Q6B_A          203 IAKTATGGGTEFLVDAKSVGIE--VPLIAGNSWDALSLTEDIENIGMTAEGLLVGSFF----------NPQ---RPDSRT  267 (356)
T ss_dssp             EESCCCCCCHHHHHHHHHHTCC--SCEEECGGGTCC-----------TTTTCEEEEEC----------CTT---CCCHHH
T ss_pred             EEecCccchHHHHHHHHHcCCC--CCEEecCccchhchHHHHHHhhhhhcCeEEEecC----------CCC---CCChhH
Confidence            76543 3567788888887773  456655544321100  00000111121111100          000   000111


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMST  436 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~  436 (908)
                      ..|.+.+++.++                           ..++.++..+|||++++++|+++...               
T Consensus       268 ~~f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~---------------  305 (356)
T 4Q6B_A          268 QDFVEAFRREYG---------------------------QPPTSYAAAGYDAVILLAEALEKSDL---------------  305 (356)
T ss_dssp             HHHHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHTSCT---------------
T ss_pred             HHHHHHHHHHHC---------------------------CCCCHHHHHHHHHHHHHHHHHHhCCC---------------
Confidence            122222222111                           11235677899999999999987642               


Q NP_000836.2     437 IDGKELLGYIRA-VNFNGSAGTPVTFNENGDAPGRYD-IFQYQITNKSTEYKVIG  489 (908)
Q Consensus       437 ~~~~~l~~~l~~-~~f~G~~G~~v~Fd~~G~~~~~~~-i~~~~~~~~~~~~~~Vg  489 (908)
                      .+++.+.+.|++ ..|.|.+| .+.|+++|++...+. +.++.    ++.++.+|
T Consensus       306 ~~~~~~~~~l~~~~~~~g~~G-~~~f~~~g~~~~~~~~~~~~~----~g~~~~~~  355 (356)
T 4Q6B_A          306 THPATLAQGLRDLGPWEGVMG-MHRFDGRGDDIGDLVVLKKMK----DGRFEYLG  355 (356)
T ss_dssp             TCGGGHHHHHHHTCSEEETTE-EECBCTTSCBCSSCEEEEEEE----TTEEEEC-
T ss_pred             CCHHHHHHHHHhhCCCCCcce-eEEECCCCCcccceEEEEEEE----CCEEEEcC
Confidence            134457777877 47899988 899999888765433 44443    24555554


No 92
>3TD9_A Branched chain amino acid ABC; leucine binding, Structural Genomics, Joint; HET: EDO, PHE; 1.9A {Thermotoga maritima}
Probab=99.51  E-value=1.1e-18  Score=186.24  Aligned_cols=347  Identities=22%  Similarity=0.238  Sum_probs=217.8  Template_Neff=11.700

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      -++++||++.|.++...          ..+.....|++.|++++|..    .|+++++.+.|+.+++..    ..+.+++
T Consensus        14 ~~~i~ig~~~p~sg~~~----------~~~~~~~~g~~~a~~~~~~~----~g~~v~l~~~d~~~~~~~----~~~~~~~   75 (366)
T 3TD9_A           14 RKVVKIAVILPMTGGIS----------AFGRMVWEGIQIAHEEKPTV----LGEEVELVLLDTRSEKTE----AANAAAR   75 (366)
T ss_dssp             --CEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHCCEE----TTEEEEEEEEECTTCHHH----HHHHHHH
T ss_pred             CCceEEEEEEccCCCch----------HHHHHHHHHHHHHHHhCCCC----CCeEEEEEEEcCCCCHHH----HHHHHHH
Confidence            46799999999987532          35677889999999988642    367788888887655332    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                  .+++++++++.++.....+...+...++|+|.+.+..+.+..  ..++++++.+++...
T Consensus        76 l~~------------------~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~~~  135 (366)
T 3TD9_A           76 AID------------------KEKVLAIIGEVASAHSLAIAPIAEENKVPMVTPASTNPLVTQ--GRKFVSRVCFIDPFQ  135 (366)
T ss_dssp             HHH------------------TSCCSEEEECSSHHHHHHHHHHHHHTTCCEEESSCCCGGGTT--TCSSEEESSCCHHHH
T ss_pred             HHH------------------hcCccEEEccCCchHHHHHHHHHHHcCCCEEccCCCCccccC--CCceeeEecCCcHHH
Confidence            332                  147889999877766666777788899999998776544322  246778888888888


Q NP_000836.2     203 AQAMVDIV-TALGWNYVSTLAS-EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l-~~~~~~~v~ii~~-~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ++.+++++ ++.+|+++++++. ++.++..+.+.+++.+++. ++++.. ..+.  ....+....+++++. .+++++++
T Consensus       136 ~~~~~~~l~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~~-g~~~~~-~~~~--~~~~~~~~~~~~~~~-~~~~~iv~  210 (366)
T 3TD9_A          136 GAAMAVFAYKNLGAKRVVVFTDVEQDYSVGLSNFFINKFTEL-GGQVKR-VFFR--SGDQDFSAQLSVAMS-FNPDAIYI  210 (366)
T ss_dssp             HHHHHHCCCCCSCCCEEEEEEETTCHHHHHHHHHHHHHHHHT-TCEEEE-EEEC--TTCCCCHHHHHHHHH-TCCSEEEE
T ss_pred             HHHHHHHHHHhcCCCEEEEEEeCCChhhHHHHHHHHHHHHHC-CCeEEE-EEEC--CCCCChHHHHHHHHh-hCCCEEEE
Confidence            88888888 5578999999984 4556667778888877765 355432 1222  122345566666663 57888877


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ...+..+..+++++++.|+..  .+++.+.+...... ........+.+......          ..  ....+....|.
T Consensus       211 ~~~~~~~~~~~~~~~~~g~~~--~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~~--~~~~~~~~~f~  275 (366)
T 3TD9_A          211 TGYYPEIALISRQARQLGFTG--YILAGDGADAPELI-EIGGEAVEGLLFTTHYH----------PK--AASNPVAKKFV  275 (366)
T ss_dssp             CSCHHHHHHHHHHHHHTTCCS--EEEECGGGCSTHHH-HHHGGGGTTCEEEESCC----------GG--GCCSHHHHHHH
T ss_pred             cCCHHHHHHHHHHHHHcCCCc--EEEecCccCcHHHH-HHhhHHhCceEEEecCC----------cc--cCCCHHHHHHH
Confidence            765566777888888888742  33433322211100 00011122322211100          00  00001111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++                           ..++.++..+|||+++++++++++..               .+++
T Consensus       276 ~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~---------------~~~~  313 (366)
T 3TD9_A          276 EVYKEKYG---------------------------KEPAALNALGYDAYMVLLDAIERAGS---------------FDRE  313 (366)
T ss_dssp             HHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHTS---------------CCHH
T ss_pred             HHHHHHHC---------------------------CCCcHHHHHHHHHHHHHHHHHHHcCC---------------CCHH
Confidence            22222111                           11234677899999999999988642               1345


Q NP_000836.2     441 ELLGYIRAV-NFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       441 ~l~~~l~~~-~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .+.++|++. .|.|.+| ++.|+++|++...+.+.+++    ++.++.+|.|++.
T Consensus       314 ~l~~~l~~~~~~~g~~G-~~~f~~~g~~~~~~~i~~~~----~~~~~~~~~w~~~  363 (366)
T 3TD9_A          314 KIAEEIRKTRNFNGASG-IINIDENGDAIKSVVVNIVK----NGSVDFEAVINPD  363 (366)
T ss_dssp             HHHHHHTTCCSEEETTE-EECBCTTSCBCCCEEEEEEE----TTEEEEEEEECGG
T ss_pred             HHHHHHHcCCCcccccE-EEEECCCCCccceEEEEEEE----CCEEEEeEEeCcc
Confidence            677777765 7889888 89999988887788888886    3578888888753


No 93
>3N0W_B ABC branched chain amino acid; Receptor family ligand binding region; HET: MSE; 1.88A {Burkholderia xenovorans}
Probab=99.50  E-value=1.7e-18  Score=185.85  Aligned_cols=350  Identities=13%  Similarity=0.170  Sum_probs=216.8  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||+++|.++...         ...+.....|++.|++++|.  + ..|+++++.+.|+.+++..    ..+.++
T Consensus         3 ~~~~~~Ig~i~~~~~~~~---------~~~~~~~~~g~~~a~~~~~~--~-~~g~~i~~~~~d~~~~~~~----~~~~~~   66 (379)
T 3N0W_B            3 STGQVTLGVLTDMSSVYA---------DSAGKGSVAAVQLAIEDVGG--K-ALGQPVKLVSADYQMKTDV----ALSIAR   66 (379)
T ss_dssp             ---CCEEEEEECSSSTTT---------TTSHHHHHHHHHHHHHTTTT--E-ETTEECEEEEEECTTCHHH----HHHHHH
T ss_pred             CCccEEEEEEecCCCcch---------hhcCHHHHHHHHHHHHHhCC--c-cCCeeEEEEEEcCCCCHHH----HHHHHH
Confidence            456899999999876421         01456788999999999972  2 2467788888887655432    333344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                  .+++++++++.++.....+...+...++|+|.+....+.+.....+++++++.++...
T Consensus        67 ~l~~------------------~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~~  128 (379)
T 3N0W_B           67 EWFD------------------RDGVDAIFDVVNSGTALAINNLVKDKKKLAFITAAAADQIGGTECNGYGIGFLYNFTS  128 (379)
T ss_dssp             HHHH------------------TSCCCEEEECCSHHHHHHHHHHHHHHTCEEEECSCCCTTTTTTTCCSSEEECSCCHHH
T ss_pred             HHHH------------------HhCCCEEEeCCCHHHHHHHHHHHHhcCCeEEEcCccccccCCCccCCceeEcccCHHH
Confidence            4332                  1478899998777666666777888899999887655443322235678888888888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++++++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..++...+++++. .++|++++.
T Consensus       129 ~~~~~~~~l~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~iv~~  204 (379)
T 3N0W_B          129 IVKTVVQAQLAKGYKTWFLMLPDAAYGDLMNAAIRRELTAG-GGQIVGSVRFP--FETQDFSSYLLQAKA-SGAQLIVST  204 (379)
T ss_dssp             HHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCCCCHHHHHHHHH-TTCSEEEEC
T ss_pred             HHHHHHHHHHHcCCCEEEEEccccHHHHHHHHHHHHHHHHC-CCEEEEEEEeC--CCCCChHHHHHHHHH-cCCCEEEEE
Confidence            88888888877899999999976677888888888888775 35554332222  122345566677663 578888777


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQE-EIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~-~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ..+..+..+++++++.|+..++.+++.. +...... .... ....+.+....          +..    ...+....|.
T Consensus       205 ~~~~~~~~~~~~~~~~g~~~~~~~~~~~-~~~~~~~-~~~~~~~~~g~~~~~~----------~~~----~~~~~~~~f~  268 (379)
T 3N0W_B          205 SGGAANINIMKQAREFGLPSKTQKVGGM-IDILTDV-KSAGLRVMQGQEYATS----------FYW----NMDDRTRAFA  268 (379)
T ss_dssp             CCHHHHHHHHHHHHTTTCSCSSCEEECC-BCCHHHH-HHHCHHHHTTCEEEES----------CCT----TSSHHHHHHH
T ss_pred             cChHHHHHHHHHHHHcCCCccceeeech-hhHHHHH-HHhchhhhcCCceecc----------ccc----CCCHHHHHHH
Confidence            6666778888898888775333333321 1110000 0000 11112111100          000    0011112222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++                           ..++.++..+|||+++++.|++++..               .+++
T Consensus       269 ~~~~~~~~---------------------------~~p~~~~~~~yda~~~~~~al~~~~~---------------~~~~  306 (379)
T 3N0W_B          269 KRFYAKMG---------------------------KMPTNNQAGGYSAALQYLKAVNAIGS---------------KDPQ  306 (379)
T ss_dssp             HHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHTC---------------CCHH
T ss_pred             HHHHHHHC---------------------------CCCChHHHHHHHHHHHHHHHHHHHCC---------------CCHH
Confidence            22222211                           11234567899999999999988642               2355


Q NP_000836.2     441 ELLGYIRAVNFN-GSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       441 ~l~~~l~~~~f~-G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                      .+.++|++..|. |.+| .+.|+++|++...+.+.+++.    .. ..+|.|..
T Consensus       307 ~l~~~l~~~~~~~g~~g-~~~f~~~~~~~~~~~i~~~~~----~~-~~~~~w~~  354 (379)
T 3N0W_B          307 KVFAYLKTIKFDDAVTR-HGTLRPGGRLVRDMYLVRAKK----PE-DQKGDWDY  354 (379)
T ss_dssp             HHHHHHTTCCBCSSSCC-SBEECTTSBEECCEEEEEECC----GG-GCCSTTCC
T ss_pred             HHHHHHhcCccccCCCC-ceeeCCCCcEEEeEEEEEEcC----Cc-cCCCChhh
Confidence            677888877786 7788 899998887777788888873    12 45677764


No 94
>1PEA_A AMIDASE OPERON, ACETAMIDE; GENE REGULATOR, RECEPTOR, BINDING PROTEIN; 2.1A {Pseudomonas aeruginosa} SCOP: c.93.1.1
Probab=99.49  E-value=1.8e-18  Score=186.08  Aligned_cols=354  Identities=11%  Similarity=0.073  Sum_probs=219.0  Template_Neff=11.900

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|.++...          ..+.....+++.|++++|+.+++. |+++++.+.|+.+++..    ..+.++
T Consensus         4 ~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~g~~~-g~~i~~~~~d~~~~~~~----~~~~~~   68 (385)
T 1PEA_A            4 HQERPLIGLLFSETGVTA----------DIERSQRYGALLAVEQLNREGGVG-GRPIETLSQDPGGDPDR----YRLCAE   68 (385)
T ss_dssp             ----CEEEEECCSSSTTH----------HHHHHHHHHHHHHHHHHHTTTTBT-TBCCEEEEECCTTCHHH----HHHHHH
T ss_pred             CCCCCEEEEEEcCCCCcc----------hHHHHHHHHHHHHHHHHHHcCCcC-CeeeEEEEECCCCCHHH----HHHHHH
Confidence            457899999999876421          256678899999999999876543 67888888887665432    233334


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                  .++++++|++.++.....+...+...++|+|++....+.    ...++++++.++...
T Consensus        69 ~l~~------------------~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~----~~~~~~~~~~~~~~~  126 (385)
T 1PEA_A           69 DFIR------------------NRGVRFLVGCYMSHTRKAVMPVVERADALLCYPTPYEGF----EYSPNIVYGGPAPNQ  126 (385)
T ss_dssp             HHHH------------------TTCCCEEEECCSHHHHHHHHHHHHHTTCEEEECSCCCCC----CCCTTEEECSCCGGG
T ss_pred             HHHH------------------hcCceEEEeccccHHHHhhHHHHhhcCCEEEecCCCCCC----CCCCcEEEecCChhh
Confidence            3332                  147889999887766667777888899999988764321    124678888888888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++.+++++.+.+|++|++++.++.++..+.+.+++.+++. ++++.....+.......++...+++++. .++|++++.
T Consensus       127 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~ii~~  204 (385)
T 1PEA_A          127 NSAPLAAYLIRHYGERVVFIGSDYIYPRESNHVMRHLYRQH-GGTVLEEIYIPLYPSDDDLQRAVERIYQ-ARADVVFST  204 (385)
T ss_dssp             THHHHHHHHHTTTCSEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEECSSCCHHHHHHHHHHHHH-HTCSEEEEE
T ss_pred             hhHHHHHHHHHHhCCcEEEEecCCcchHHHHHHHHHHHHHC-CCeEEEEEEeCCCCCchhHHHHHHHHHH-cCCCEEEEE
Confidence            88889999887899999999976677778888888888765 3555432211110112345566666663 578888777


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ..+..+..+++++++.|+.. .+.|+..+ ...... .........+.+...+..          .   ....+....|.
T Consensus       205 ~~~~~~~~~~~~~~~~g~~~~~~~~~~~~-~~~~~~-~~~~~~~~~~~~~~~~~~----------~---~~~~~~~~~f~  269 (385)
T 1PEA_A          205 VVGTGTAELYRAIARRYGDGRRPPIASLT-TSEAEV-AKMESDVAEGQVVVAPYF----------S---SIDTPASRAFV  269 (385)
T ss_dssp             CCTHHHHHHHHHHHHHHCSSCCCCEEESS-CCHHHH-TTSCHHHHTTCEEEESCC----------T---TCSSHHHHHHH
T ss_pred             ccchHHHHHHHHHHHHhCCCCCCCeeEee-CCHHHH-HhcccchhcCCEEEeccc----------c---CCCCHHHHHHH
Confidence            66667778888888877542 33444332 111000 000011122222111100          0   00011112222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++.                         ...+..++..+||++++++.++++...               .+++
T Consensus       270 ~~~~~~~~~-------------------------~~~~~~~~~~~yda~~~~~~a~~~~~~---------------~~~~  309 (385)
T 1PEA_A          270 QACHGFFPE-------------------------NATITAWAEAAYWQTLLLGRAAQAAGN---------------WRVE  309 (385)
T ss_dssp             HHHHTTSCT-------------------------TCCCCHHHHHHHHHHHHHHHHHHHHTS---------------CCHH
T ss_pred             HHHHHhCCC-------------------------CCCCCHHHHHHHHHHHHHHHHHHHhCC---------------CCHH
Confidence            222221110                         011234677899999999999987642               1345


Q NP_000836.2     441 ELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       441 ~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                      .+.+.|++..|.|.+| ++.|+++|++. ..+.+.+++.   ++.++.++.++.
T Consensus       310 ~l~~~l~~~~~~g~~g-~~~f~~~~~~~~~~~~i~~~~~---~g~~~~~~~~~~  359 (385)
T 1PEA_A          310 DVQRHLYDIDIDAPQG-PVRVERQNNHSRLSSRIAEIDA---RGVFQVRWQSPE  359 (385)
T ss_dssp             HHHHHHTTCCEEETTE-EEEECTTTSCEEBCCEEEEECT---TSCEEEEEECSS
T ss_pred             HHHHHHhcCCcccCCc-eEEEeCCCCeeeeeeEEEEEcC---CCCEeEEEeCCC
Confidence            6778888888999988 89999766653 4667777752   246777776654


No 95
>1QO0_B AMIC, AMIR; BINDING PROTEIN, GENE REGULATOR, RECEPTOR; HET: BMD; 2.25A {PSEUDOMONAS AERUGINOSA} SCOP: c.93.1.1
Probab=99.49  E-value=1.8e-18  Score=186.08  Aligned_cols=354  Identities=11%  Similarity=0.073  Sum_probs=219.8  Template_Neff=11.900

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|.++...          ..+.....+++.|++++|+.+++. |+++++.+.|+.+++..    ..+.++
T Consensus         4 ~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~g~~~-g~~i~~~~~d~~~~~~~----~~~~~~   68 (385)
T 1QO0_B            4 HQERPLIGLLFSETGVTA----------DIERSQRYGALLAVEQLNREGGVG-GRPIETLSQDPGGDPDR----YRLCAE   68 (385)
T ss_dssp             ---CCEEEEECCSSSTTH----------HHHHHHHHHHHHHHHHHHHTTTBT-TBCCEEEECCCTTCHHH----HHHHHH
T ss_pred             CCCCCEEEEEEcCCCCcc----------hHHHHHHHHHHHHHHHHHHcCCcC-CeeeEEEEECCCCCHHH----HHHHHH
Confidence            457899999999876421          256678899999999999876543 67888888887665432    233334


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                  .++++++|++.++.....+...+...++|+|++....+.    ...++++++.++...
T Consensus        69 ~l~~------------------~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~----~~~~~~~~~~~~~~~  126 (385)
T 1QO0_B           69 DFIR------------------NRGVRFLVGCYMSHTRKAVMPVVERADALLCYPTPYEGF----EYSPNIVYGGPAPNQ  126 (385)
T ss_dssp             HHHH------------------HSCCCEEEECCSHHHHHHHHHHHHHHTCEEEECSCCCCC----CCCTTEEECSCCGGG
T ss_pred             HHHH------------------hcCceEEEeccccHHHHhhHHHHhhcCCEEEecCCCCCC----CCCCcEEEecCChhh
Confidence            3332                  147889999887766667777888899999988764321    124678888888888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++.+++++.+.+|++|++++.++.++..+.+.+++.+++. ++++.....+.......++...+++++. .++|++++.
T Consensus       127 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~ii~~  204 (385)
T 1QO0_B          127 NSAPLAAYLIRHYGERVVFIGSDYIYPRESNHVMRHLYRQH-GGTVLEEIYIPLYPSDDDLQRAVERIYQ-ARADVVFST  204 (385)
T ss_dssp             THHHHHHHHHHHSCSEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEECSSCCHHHHHHHHHHHHH-HTCSEEEEE
T ss_pred             hhHHHHHHHHHHhCCcEEEEecCCcchHHHHHHHHHHHHHC-CCeEEEEEEeCCCCCchhHHHHHHHHHH-cCCCEEEEE
Confidence            88889999887899999999976677778888888888765 3555432211110112345566666663 578888777


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ..+..+..+++++++.|+.. .+.|+..+ ...... .........+.+...+..          .   ....+....|.
T Consensus       205 ~~~~~~~~~~~~~~~~g~~~~~~~~~~~~-~~~~~~-~~~~~~~~~~~~~~~~~~----------~---~~~~~~~~~f~  269 (385)
T 1QO0_B          205 VVGTGTAELYRAIARRYGDGRRPPIASLT-TSEAEV-AKMESDVAEGQVVVAPYF----------S---SIDTPASRAFV  269 (385)
T ss_dssp             CCSTTHHHHHHHHHHHSCSSSCCCEEESS-CCHHHH-TTSCHHHHTTCEEEESCC----------T---TCCSHHHHHHH
T ss_pred             ccchHHHHHHHHHHHHhCCCCCCCeeEee-CCHHHH-HhcccchhcCCEEEeccc----------c---CCCCHHHHHHH
Confidence            66667778888888877542 33444332 111000 000011122222111100          0   00011112222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++.                         ...+..++..+||++++++.++++...               .+++
T Consensus       270 ~~~~~~~~~-------------------------~~~~~~~~~~~yda~~~~~~a~~~~~~---------------~~~~  309 (385)
T 1QO0_B          270 QACHGFFPE-------------------------NATITAWAEAAYWQTLLLGRAAQAAGN---------------WRVE  309 (385)
T ss_dssp             HHHHTTSCT-------------------------TCCCCHHHHHHHHHHHHHHHHHHHHTS---------------CCHH
T ss_pred             HHHHHhCCC-------------------------CCCCCHHHHHHHHHHHHHHHHHHHhCC---------------CCHH
Confidence            222221110                         011234677899999999999987642               1345


Q NP_000836.2     441 ELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       441 ~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                      .+.+.|++..|.|.+| ++.|+++|++. ..+.+.+++.   ++.++.++.++.
T Consensus       310 ~l~~~l~~~~~~g~~g-~~~f~~~~~~~~~~~~i~~~~~---~g~~~~~~~~~~  359 (385)
T 1QO0_B          310 DVQRHLYDIDIDAPQG-PVRVERQNNHSRLSSRIAEIDA---RGVFQVRWQSPE  359 (385)
T ss_dssp             HHHHTTTTCCEEETTE-EEEECTTTSBEEBCCEEEEECT---TSCEEEEEECSS
T ss_pred             HHHHHHhcCCcccCCc-eEEEeCCCCeeeeeeEEEEEcC---CCCEeEEEeCCC
Confidence            6778888888999988 89999766653 4667777752   246777776654


No 96
>4KV7_A Probable leucine/isoleucine/valine-binding protein; structural genomics, PSI-Biology, Protein Structure; 1.2A {Rhodopirellula baltica}
Probab=99.49  E-value=1.9e-18  Score=185.53  Aligned_cols=349  Identities=15%  Similarity=0.149  Sum_probs=214.2  Template_Neff=11.900

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ......++++||+++|.++...          ..+.....+++.|++++|+.+++. |+++++.+.|+++++..    ..
T Consensus        10 ~~~~~~~~~~Ig~~~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~~~~~-g~~i~~~~~d~~~~~~~----~~   74 (381)
T 4KV7_A           10 ATPVDAQLLKFGMSTALSGPAA----------ELGINMRHGILAAFDEAKAKNHLP-SKTLKLIALDDGYEPAR----TA   74 (381)
T ss_dssp             CCCCCCEEEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHHHHTTSST-TEEEEEEEEECTTCHHH----HH
T ss_pred             CCCCCcceEEEEEEeCCCCccH----------HHHHHHHHHHHHHHHHHHHhCCCC-CceeEEEEEcCCCCHhh----HH
Confidence            3455678999999999876421          256678899999999999876543 67888888887766433    33


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +.+++++.                  .++++++|++.++.....+...+...+||+|.+....+.+.....+++++++.+
T Consensus        75 ~~~~~l~~------------------~~~~~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~  136 (381)
T 4KV7_A           75 PNMHRLTD------------------EHEVLAVVGNVGTPTAITAIPIAQQTKTPFFGAFTGASALRKTESVEFVINYRA  136 (381)
T ss_dssp             HHHHHHHT------------------TTCCSCEECCBCHHHHHHHHHHHHHTTCCEESCBCCCGGGCC---CTTEEBCSC
T ss_pred             HHHHHHHh------------------hCCeeEEEeCCCcHHHHHHHHHHHhhCCCEEeeecCchHhcCCCCCceEEECCc
Confidence            33444332                  147889999887776677778888999999998776554432224677888989


Q NP_000836.2     198 PDSYQAQAMVDIVTA--LGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQ--KIPREPRPGEFEKIIKRLLE-T  272 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~--~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~--~~~~~~~~~~~~~~~~~l~~-~  272 (908)
                      +....+.++++++.+  .+|++|++++.++.++....+.+.+.+++..++++....  .+.  .+..++...+++++. .
T Consensus       137 ~~~~~~~~~~~~l~~~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~g~~v~~~~~~~~~--~~~~~~~~~~~~~~~~~  214 (381)
T 4KV7_A          137 SYAEETAAMVDALVAKGIKPEEIGFFTQNDSYGDDGFFGGLAAIRRHQSVKVSSLPHGRYR--RNTSQVEDGLADLLMHQ  214 (381)
T ss_dssp             CHHHHHHHHHHHHHHTTCCGGGEEEEEESSHHHHHHHHHHHHHHHHHSCCCGGGSCEEEEC--TTCCCCHHHHHHHHTCS
T ss_pred             CHHHHHHHHHHHHHHCCCCccEEEEEEeCCcchHhhHHHHHHHHHHcCCCcceecCCCCCC--CCCccHHHHHHHHHhcC
Confidence            888888889988854  578999999976667777777888777652134443211  111  112344555666541 2


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLAN  352 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~  352 (908)
                      .++|+|++...+..+..+++++++.|+.  ..|++.+.+...... ........+.+.......        .    ...
T Consensus       215 ~~~~~i~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~--------~----~~~  279 (381)
T 4KV7_A          215 PLPKAVIMVGTYEPCSKLIRMARMNNFN--PQFLAVSFVGADALQ-RSLGDLANGIVATQVVPH--------F----DSD  279 (381)
T ss_dssp             SCCSEEEEESCHHHHHHHHHHHHHTTCC--CEEEECGGGCHHHHH-HHHGGGGTTCEEEESSCC--------T----TCC
T ss_pred             CCCCEEEEECChHHHHHHHHHHHhCCCC--CcEEEEeccCHHHHH-HHHHHhcccEEEEEeeCC--------C----CCC
Confidence            4688887776666677888888887764  345554433221110 000111222221110000        0    000


Q NP_000836.2     353 NRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCP  432 (908)
Q Consensus       353 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~  432 (908)
                      .+....|.+.+++.+..                          .....++..+|||++++++++++....          
T Consensus       280 ~~~~~~f~~~~~~~~~~--------------------------~~~~~~~~~~yda~~~~~~al~~~~~~----------  323 (381)
T 4KV7_A          280 LPLVREYRDAMRDYDPE--------------------------LPLSFVSLEGYIVGRILVKAVTSIKGE----------  323 (381)
T ss_dssp             SHHHHHHHHHHHHHCTT--------------------------SCCCHHHHHHHHHHHHHHHHHHHCCSC----------
T ss_pred             CHHHHHHHHHHHHhCCC--------------------------CCCChhhHHHHHHHHHHHHHHHhcCCC----------
Confidence            01111222222211110                          112345778999999999999876421          


Q NP_000836.2     433 RMSTIDGKELLGYIRAV-NFN-GSAGTPVTFNENGDAP-GRYDIFQYQ  477 (908)
Q Consensus       433 ~~~~~~~~~l~~~l~~~-~f~-G~~G~~v~Fd~~G~~~-~~~~i~~~~  477 (908)
                          .+++.+.+.|++. .|. |.+| ++.|+++|++. ..+.+++++
T Consensus       324 ----~~~~~l~~~l~~~~~~~~g~~g-~i~f~~~~~~~~~~~~i~~~~  366 (381)
T 4KV7_A          324 ----ISRSSIAAALEQLGQFDIGLGA-PLTLGPNDHQASSKVWPVLIG  366 (381)
T ss_dssp             ----CCHHHHHHHHHHTEEECSSSSS-CEEEBTTBCBCCCCCEEEEEC
T ss_pred             ----CCHHHHHHHHHHcCCCcCCCCC-CcccCCCCCcccccEEEEEEc
Confidence                2345677788766 787 7777 89999876543 456666665


No 97
>4OBB_B Amino acid/amide ABC transporter substrate-binding; STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER; HET: 1QQ, MSE; 1.526A {Anabaena variabilis}
Probab=99.49  E-value=2e-18  Score=186.37  Aligned_cols=362  Identities=16%  Similarity=0.184  Sum_probs=213.9  Template_Neff=11.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||+++|.++...          ..+.....+++.|++++|+.+++ .|+++++.+.|+.+++..    ..+
T Consensus        27 ~~~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~~~~-~g~~i~~~~~d~~~~~~~----~~~   91 (395)
T 4OBB_B           27 TTSDKNTIPIGIALAQTSNVA----------LLGQEQVAGAKIAEKYFNDKGGV-NGTPIKLIFQDTAGDEAG----TIN   91 (395)
T ss_dssp             -----CCEEEEECCCCSSTTH----------HHHHHHHHHHHHHHHHHHHTTTB-TTBCEEEEECCCTTSHHH----HHH
T ss_pred             CCccCCcEEEEEEECCCCCcH----------HHHHHHHHHHHHHHHHHHHcCCC-CCeeeEEEEEcCCCCHHH----HHH
Confidence            345678999999999875321          24567889999999999987654 367788887776655332    233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+++++.+                  .+++++|++.++.....+...+...+||+|.+....+.+..  .+++++++.++
T Consensus        92 ~~~~l~~~------------------~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~  151 (395)
T 4OBB_B           92 AFQTLINK------------------DKVVGIVGPTLSQQAFSANPIAERAKVPVVGPSNTAKGIPE--IGDYVARVSAP  151 (395)
T ss_dssp             HHHCCCCC------------------SCCSCEECCSCHHHHHHHHHHHHHHTCCEEESSCCSTTSGG--GCTTEEESSCC
T ss_pred             HHHHHHhc------------------CCccEEECCCChhHHHHHHHHHHHhCCCEEcCCcCCCcCCC--CCCeEEEecCC
Confidence            33433321                  46788888876665566677788899999998765543321  24677888888


Q NP_000836.2     199 DSYQAQAMVDIVT--ALGWNYVSTLA-SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       199 ~~~~~~~~~~~l~--~~~~~~v~ii~-~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~  275 (908)
                      +...+..+++.+.  ..+|+++++++ .++.++..+.+.|++.+++. ++++.....+.  ....+....+++++. .++
T Consensus       152 ~~~~~~~~~~~l~~~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~  227 (395)
T 4OBB_B          152 VSVVAPNSVKAALKQNPNIKKVAVFFAQNDAFSKSETEIFQQTVKDQ-GLELVTVQKFQ--TTDTDFQSQATNAIN-LKP  227 (395)
T ss_dssp             HHHHTHHHHHHHHHHCTTCCEEEEEEETTCHHHHHHHHHHHHHHHHH-TCEEEEEEEEC--TTCCCCHHHHHHHHT-TCC
T ss_pred             hHHhchHHHHHHHHhCCCCCEEEEEEecCChHhHHHHHHHHHHHHHC-CCeEEEEEEeC--CCCCCHHHHHHHHHh-hCC
Confidence            8777777776543  56899999998 45556777788888887765 35544322222  122344555666653 478


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR  355 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  355 (908)
                      ++|++...+..+..+++++++.|+.  ..|++.+.+...... ........+.+......          .   ....+.
T Consensus       228 ~~i~~~~~~~~~~~~~~~~~~~g~~--~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~---~~~~~~  291 (395)
T 4OBB_B          228 DLVIISGLAADGGNLVRQLRELGYQ--GAIIGGNGLNTSNVF-AVCKALCDGVLIAQAYS----------P---EYTGEI  291 (395)
T ss_dssp             SEEEEESCHHHHHHHHHHHHHTTCC--SEEEECGGGCSGGGH-HHHGGGGTTCEEEESCC----------T---TCCCHH
T ss_pred             CEEEEECChhhHHHHHHHHHHcCCC--ceEEecCccCCHHHH-HHhHHHhCCeEEeecCC----------c---ccCCHH
Confidence            8887776566677888888888774  356655433221100 00011122222111100          0   000011


Q NP_000836.2     356 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMS  435 (908)
Q Consensus       356 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~  435 (908)
                      ...|.+.+.+.++                           ..+..++..+|||++++++++++.......    .+. ..
T Consensus       292 ~~~f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~~~~~----~~~-~~  339 (395)
T 4OBB_B          292 NKAFRQAYVDQYK---------------------------KEPPQFSAQAFAAVQVYVESLKALDTKNKV----SKI-QL  339 (395)
T ss_dssp             HHHHHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHHHHSCG----GGS-CH
T ss_pred             HHHHHHHHHHHHC---------------------------CCCChHHHHHHHHHHHHHHHHHHccccCCC----ccc-cH
Confidence            1122222222111                           112356788999999999999887642100    000 00


Q NP_000836.2     436 TIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       436 ~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      ....+.+.+.+++..|.|.+| ++.||++|++. ..+.+++++.    ..+..+|.|.
T Consensus       340 ~~~~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~~i~~~~~----~~~~~~~~~~  392 (395)
T 4OBB_B          340 PELRTELNKQLLTGKYNTPLG-EISFTPIGEVVQKDFYVAQIKM----EKDGSQGKFT  392 (395)
T ss_dssp             HHHHHHHHHHHHHCEEEETTE-EEEECTTSCEECCCCEEEEEEE----CTTSSCEEEE
T ss_pred             HHHHHHHHHHHhhCCCcCCcE-EEEECCCCCccCccEEEEEEEc----cccCCcceEE
Confidence            011223444455568999988 89999988875 6788888763    2344556554


No 98
>4RV5_B Amino acid/amide ABC transporter substrate-binding; Structural Genomics, PSI-Biology, Protein Structure; HET: PYR, MSE, FMT; 1.04A {Anabaena variabilis ATCC 29413}
Probab=99.49  E-value=2e-18  Score=186.37  Aligned_cols=362  Identities=16%  Similarity=0.184  Sum_probs=213.9  Template_Neff=11.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||+++|.++...          ..+.....+++.|++++|+.+++ .|+++++.+.|+.+++..    ..+
T Consensus        27 ~~~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~~~~-~g~~i~~~~~d~~~~~~~----~~~   91 (395)
T 4RV5_B           27 TTSDKNTIPIGIALAQTSNVA----------LLGQEQVAGAKIAEKYFNDKGGV-NGTPIKLIFQDTAGDEAG----TIN   91 (395)
T ss_dssp             -----CCEEEEECCCCSSTTH----------HHHHHHHHHHHHHHHHHHHTTTB-TTBCEEEEECCCTTSHHH----HHH
T ss_pred             CCccCCcEEEEEEECCCCCcH----------HHHHHHHHHHHHHHHHHHHcCCC-CCeeeEEEEEcCCCCHHH----HHH
Confidence            345678999999999875321          24567889999999999987654 367788887776655332    233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+++++.+                  .+++++|++.++.....+...+...+||+|.+....+.+..  .+++++++.++
T Consensus        92 ~~~~l~~~------------------~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~  151 (395)
T 4RV5_B           92 AFQTLINK------------------DKVVGIVGPTLSQQAFSANPIAERAKVPVVGPSNTAKGIPE--IGDYVARVSAP  151 (395)
T ss_dssp             HHHHHHHT------------------SCCSCEECCSCHHHHHHHHHHHHHHTCCEEESSCCSTTSGG--GCTTEEESSCC
T ss_pred             HHHHHHhc------------------CCccEEECCCChhHHHHHHHHHHHhCCCEEcCCcCCCcCCC--CCCeEEEecCC
Confidence            33433321                  46788888876665566677788899999998765543321  24677888888


Q NP_000836.2     199 DSYQAQAMVDIVT--ALGWNYVSTLA-SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       199 ~~~~~~~~~~~l~--~~~~~~v~ii~-~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~  275 (908)
                      +...+..+++.+.  ..+|+++++++ .++.++..+.+.|++.+++. ++++.....+.  ....+....+++++. .++
T Consensus       152 ~~~~~~~~~~~l~~~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~  227 (395)
T 4RV5_B          152 VSVVAPNSVKAALKQNPNIKKVAVFFAQNDAFSKSETEIFQQTVKDQ-GLELVTVQKFQ--TTDTDFQSQATNAIN-LKP  227 (395)
T ss_dssp             HHHHHHHHHHHHHHHCTTCCEEEEEEETTCHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCCCCHHHHHHHHT-TCC
T ss_pred             hHHhchHHHHHHHHhCCCCCEEEEEEecCChHhHHHHHHHHHHHHHC-CCeEEEEEEeC--CCCCCHHHHHHHHHh-hCC
Confidence            8777777776543  56899999998 45556777788888887765 35544322222  122344555666653 478


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR  355 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  355 (908)
                      ++|++...+..+..+++++++.|+.  ..|++.+.+...... ........+.+......          .   ....+.
T Consensus       228 ~~i~~~~~~~~~~~~~~~~~~~g~~--~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~---~~~~~~  291 (395)
T 4RV5_B          228 DLVIISGLAADGGNLVRQLRELGYQ--GAIIGGNGLNTSNVF-AVCKALCDGVLIAQAYS----------P---EYTGEI  291 (395)
T ss_dssp             SEEEEESCHHHHHHHHHHHHHTTCC--SEEEECGGGCSGGGH-HHHGGGGTTCEEEESCC----------T---TCCCHH
T ss_pred             CEEEEECChhhHHHHHHHHHHcCCC--ceEEecCccCCHHHH-HHhHHHhCCeEEeecCC----------c---ccCCHH
Confidence            8887776566677888888888774  356655433221100 00011122222111100          0   000011


Q NP_000836.2     356 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMS  435 (908)
Q Consensus       356 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~  435 (908)
                      ...|.+.+.+.++                           ..+..++..+|||++++++++++.......    .+. ..
T Consensus       292 ~~~f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~~~~~----~~~-~~  339 (395)
T 4RV5_B          292 NKAFRQAYVDQYK---------------------------KEPPQFSAQAFAAVQVYVESLKALDTKNKV----SKI-QL  339 (395)
T ss_dssp             HHHHHHHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHHHHSCG----GGS-CH
T ss_pred             HHHHHHHHHHHHC---------------------------CCCChHHHHHHHHHHHHHHHHHHccccCCC----ccc-cH
Confidence            1122222222111                           112356788999999999999887642100    000 00


Q NP_000836.2     436 TIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       436 ~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      ....+.+.+.+++..|.|.+| ++.||++|++. ..+.+++++.    ..+..+|.|.
T Consensus       340 ~~~~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~~i~~~~~----~~~~~~~~~~  392 (395)
T 4RV5_B          340 PELRTELNKQLLTGKYNTPLG-EISFTPIGEVVQKDFYVAQIKM----EKDGSQGKFT  392 (395)
T ss_dssp             HHHHHHHHHHHHHCEEEETTE-EEEECTTSCEECCCCEEEEEEE----CTTSSCEEEE
T ss_pred             HHHHHHHHHHHhhCCCcCCcE-EEEECCCCCccCccEEEEEEEc----cccCCcceEE
Confidence            011223444455568999988 89999988875 6788888763    2344556554


No 99
>3I45_A Twin-arginine translocation pathway signal protein; STRUCTURAL GENOMICS, CRYSTAL STRUCTURE,PROTEIN STRUCTURE; 1.36A {Rhodospirillum rubrum}
Probab=99.49  E-value=2.3e-18  Score=185.44  Aligned_cols=355  Identities=15%  Similarity=0.137  Sum_probs=214.7  Template_Neff=11.600

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.++..           ..+.....|++.|++++|+.+++++|+++++...|+.+++..    ..+.+++
T Consensus         3 ~~~~~Ig~i~~~~~~~-----------~~~~~~~~g~~~a~~~~n~~~g~~~g~~v~~~~~d~~~~~~~----~~~~~~~   67 (387)
T 3I45_A            3 LEAIRIGEINSYSQIP-----------AFTLPYRNGWQLAVEQINAAGGLLGGRPLEVISRDDGGDPGK----AVTAAQE   67 (387)
T ss_dssp             CCCEEEEEEECTTTCH-----------HHHHHHHHHHHHHHHHHHHTTCBTTTBCEEEEEEECTTCHHH----HHHHHHH
T ss_pred             CCcEEEEEecCCCCCc-----------ccCHHHHHHHHHHHHHHHHCCCccCCceeEEEEecCCCCHHH----HHHHHHH
Confidence            4689999999987532           245678899999999999987776678888888877655332    2333444


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                  .++++++|++.++.....+...+...++|+|.+....+.+.+...+++++++.+++...
T Consensus        68 l~~------------------~~~v~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~  129 (387)
T 3I45_A           68 LLT------------------RHGVHALAGTFLSHVGLAVSDFARQRKVLFMASEPLTDALTWEKGNRYTYRLRPSTYMQ  129 (387)
T ss_dssp             HHH------------------HHCCSEEEECCSHHHHHHHHHHHHHHTCCEEECSCCCGGGTTTTCCTTEEECSCCHHHH
T ss_pred             HHH------------------HhCCCEEEEcCChHHHHHHHHHHHHcCCEEEEcCCCChhHhhcCCCCcEEEeCCCHHHH
Confidence            332                  14789999987776666667778888999998776554433222357788999988888


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQ-KIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~-~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      +..+++++.+.+|+++++++.++.++..+.+.+++.+++. +..+.... .+.. ....+....+++++. .++|++++.
T Consensus       130 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~-~~~~~~~~~~~~~~~-~~~~~ii~~  206 (387)
T 3I45_A          130 AAMLAAEAAKLPITRWATIAPNYEYGQSAVARFKELLLAA-RPEVTFVAEQWPA-LYKLDAGPTVQALQQ-AEPEGLFNV  206 (387)
T ss_dssp             HHHHHHHHTTSSCCEEEEECCSSHHHHHHHHHHHHHHHHH-CTTCEEEEEECCC-TTCCCHHHHHHHHHH-TCCSEEEEC
T ss_pred             HHHHHHHHhcCCCCEEEEEccCcHHhHHHHHHHHHHHHHh-CCCcEEEeeeccc-ccCCCcHHHHHHHHh-cCCCeEEEE
Confidence            8899999888899999999976667777888888877764 22221111 1110 112344555666653 478888777


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQE-EIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~-~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ..+..+..+++++++.|+.....++ .......... .... ....+.+.....          +.   ....+....|.
T Consensus       207 ~~~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~~---~~~~~~~~~f~  271 (387)
T 3I45_A          207 LFGADLPKFVREGRVRGLFAGRQVV-SMLTGEPEYL-NPLKDEAPEGWIVTGYP----------WY---DIDTAPHRAFV  271 (387)
T ss_dssp             CCTTHHHHHHHHHHHHTSSTTCEEE-EEEEESHHHH-GGGGGGCCSSCEEEECC----------GG---GCCCHHHHHHH
T ss_pred             cccccHHHHHHHHHHcCccCCCeEE-EEecCCHHHH-HhhcCCCCCCeEEecCC----------cc---cCCCHHHHHHH
Confidence            5566677888888888775311111 1111111000 0000 111222111000          00   00011111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+.+.+.                           ..+..++..+||++++++.|++++..               .+++
T Consensus       272 ~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~a~~~~~~---------------~~~~  309 (387)
T 3I45_A          272 EAYRARWK---------------------------EDPFVGSLVGYNTLTAMAVAFEKAGG---------------TESE  309 (387)
T ss_dssp             HHHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHTS---------------CCHH
T ss_pred             HHHHHHHC---------------------------CCCChHHHHHHHHHHHHHHHHHHhCC---------------CCHH
Confidence            22222111                           11234567899999999999988642               1345


Q NP_000836.2     441 ELLGYIRAVNFNGSAGTPVTFNE-NGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       441 ~l~~~l~~~~f~G~~G~~v~Fd~-~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .+.++|++..|.|.+| ++.|++ +++....+.+.+++..+  +.+ .++.|...
T Consensus       310 ~i~~~l~~~~~~g~~G-~i~f~~~~~~~~~~~~i~~~~~~~--g~~-~~~~w~~~  360 (387)
T 3I45_A          310 TLVETLKDMAFSTPMG-PLSFRASDHQSTMGAWVGRTALRD--GKG-VMVDWRYV  360 (387)
T ss_dssp             HHHHHTTTCEEEETTE-EEEBCTTTCBBCCCEEEEEEEEET--TEE-EEEEEEEE
T ss_pred             HHHHHHhhCcccCCCe-eEEEcCCCCcccccEEEEEEEeeC--Cce-eEeeeEEE
Confidence            6778888778999988 899987 34444566776665321  233 34466543


No 100
>4F06_A Extracellular ligand-binding receptor; PSI-BIOLOGY, MCSG, MIDWEST CENTER FOR; HET: PHB, SO4, GOL; 1.3A {Rhodopseudomonas palustris}
Probab=99.48  E-value=2.9e-18  Score=183.24  Aligned_cols=356  Identities=12%  Similarity=0.097  Sum_probs=217.6  Template_Neff=12.000

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCS-RDTYALEQSLTFV  120 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~-~~~~a~~~~~~~~  120 (908)
                      ..++++||++.|.++...          ..+.....|++.|++++|.  + ..|+++++.+.|+.+ ++..    ..+.+
T Consensus         2 ~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~~--~-~~g~~~~~~~~d~~~~~~~~----~~~~~   64 (371)
T 4F06_A            2 NADTIKVGVIGTMSGPYA----------LFGKNYKMGIDAWVAEHGN--K-VAGHTVEFVYRDEVSPNPAQ----SKALA   64 (371)
T ss_dssp             --CEEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHCS--E-ETTEEEEEEEEECCSSCHHH----HHHHH
T ss_pred             cCCceEEEEEEcCCCChh----------HhHHHHHHHHHHHHHHcCC--c-cCCEEEEEEEecCCCCCHHH----HHHHH
Confidence            356899999999875421          2556788899999999883  1 246778888877664 4332    22333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                  .++++++|++.++.....+...+...++|+|.+....+.+..  ..++++++.++..
T Consensus        65 ~~l~~------------------~~~~~~vi~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~--~~~~~~~~~~~~~  124 (371)
T 4F06_A           65 QELIV------------------KEKVQYLAGLYFTPNAMAVAPLLQEAKVPMVVMNAATSSITE--KSPYIVRTSFTMF  124 (371)
T ss_dssp             HHHHH------------------TSCCSEEEECCSHHHHHHHGGGHHHHTCCEEESSCCCGGGGG--GCTTEEESSCCHH
T ss_pred             HHHHH------------------hcCCCEEEeCCCCHHHHHHHHHHHHcCCCEEEecCCCchhcc--CCCCEEEecCchh
Confidence            44332                  157899999776666666677788899999998765543322  2567888888888


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ..+..+++++.+.+|++|++++.++.++..+.+.+.+.+++. ++++.....+.  ....+....+++++. .++|++++
T Consensus       125 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i~~  200 (371)
T 4F06_A          125 QNTVPAAKVAKQKGATKVAIAVSDYGPGIDAETAFKKTFEAE-GGKVVEAVRMP--LSTTDFGPIMQRIKN-SGADMIFT  200 (371)
T ss_dssp             HHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCCCCHHHHHHHHH-HTCSEEEE
T ss_pred             hcHHHHHHHHHHhCCCEEEEEEeCCcccHHHHHHHHHHHHHC-CCEEcEEEEcC--CCCCChHHHHHHHHH-cCCCEEEE
Confidence            888888888888899999999966667777788888887765 35544322222  122344556666653 47888877


Q NP_000836.2     281 FA-NEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVW  358 (908)
Q Consensus       281 ~~-~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  358 (908)
                      .+ ++..+..+++++++.|+.. ++.|++.+.+...... ........+.+.....          ..   ....+....
T Consensus       201 ~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~----------~~---~~~~~~~~~  266 (371)
T 4F06_A          201 FLPAGPPTLGFVKAYIDNGLKAGGVKLMSTGDVVTEPDL-PNIGEAGLGILSTYHY----------AV---SHDSPENKA  266 (371)
T ss_dssp             ECCTTHHHHHHHHHHHHTTTTTTTCEEEEEGGGGCGGGH-HHHCGGGTTCEEEESC----------CT---TCCSHHHHH
T ss_pred             eCCCChhHHHHHHHHHHCCcccCCceEEEeCCCCCCcch-hhhhhhcceeEEEecc----------cc---cCCCHHHHH
Confidence            65 4556778888988888753 3566665433221110 0011111222211100          00   000111122


Q NP_000836.2     359 FAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTID  438 (908)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~  438 (908)
                      |.+.+++.+..                         ...+..++..+||++++++++++++...              .+
T Consensus       267 f~~~~~~~~~~-------------------------~~~~~~~~~~~yda~~~~~~al~~~~~~--------------~~  307 (371)
T 4F06_A          267 FLALLQKGGAK-------------------------LDEVTMTSVAAYDGARLIYKMIEATSGK--------------SD  307 (371)
T ss_dssp             HHHHHHHTTCC-------------------------GGGCCHHHHHHHHHHHHHHHHHHHTTTS--------------CC
T ss_pred             HHHHHHHcCCC-------------------------CCCCChHHHHHHHHHHHHHHHHHHcCCC--------------CC
Confidence            33323221100                         0012346778999999999999876421              23


Q NP_000836.2     439 GKELLGYIRAVNFNGSAGTPVTFNEN-GDAPGRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       439 ~~~l~~~l~~~~f~G~~G~~v~Fd~~-G~~~~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      ++.+.+.|++.+|.|.+| ++.|+++ +++...+.+.+++..++...++.++.|.
T Consensus       308 ~~~l~~~l~~~~~~g~~g-~~~f~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~  361 (371)
T 4F06_A          308 PDKAIAAVKGMKWVSPRG-EVSIDPETRHITQNVYLREVEKVDGKLINRELETFK  361 (371)
T ss_dssp             HHHHHHHHTTCEEEETTE-EEEECTTTCBEEEEEEEEEEEEETTEEEEEEEEEEE
T ss_pred             HHHHHHHHcCCCeecCCe-eEEEcccCCceeeeEEEEEEEeeCCEEEeeeeeecc
Confidence            456778888888999888 8999974 4445677787776321123455555553


No 101
>4N03_A ABC-type branched-chain amino acid transport; structural genomics, fatty acid, PSI-Biology; HET: PLM; 1.15A {Thermomonospora curvata}
Probab=99.46  E-value=4.8e-18  Score=184.10  Aligned_cols=356  Identities=14%  Similarity=0.094  Sum_probs=221.3  Template_Neff=11.800

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||++.|.++...          ..+.....+++.|++++|+.+++ .|+++++.+.|+.+++..    ..+.
T Consensus        28 ~~~~~~i~Ig~i~~~~~~~~----------~~~~~~~~~~~~a~~~~n~~g~~-~g~~i~~~~~d~~~~~~~----~~~~   92 (405)
T 4N03_A           28 GVTDKTIKLGIATDLTGVYA----------PLGKSITQAQQLYYEEVNQRGGV-CGRTIEAVVRDHGYDPQK----AVSI   92 (405)
T ss_dssp             TBCSSEEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHHHHTTCB-TTBEEEEEEEECTTCHHH----HHHH
T ss_pred             CcCCCeEEEEEEeCCCCCCc----------chhHHHHHHHHHHHHHHHHcCCc-CCEeEEEEEEeCCCCHHH----HHHH
Confidence            45678999999999875321          24567889999999999987654 367888888887655332    2233


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++++                    ++++++|++.++.....+...+...++|+|....... ..   ..++++++.+++
T Consensus        93 ~~~l~--------------------~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~-~~---~~~~~~~~~~~~  148 (405)
T 4N03_A           93 YTELN--------------------NNVLAIPHFLGSPMVSAVKQRIESDKMFTIPSAWTTA-LL---GSKYIQVTGTTY  148 (405)
T ss_dssp             HHHHT--------------------TTCSCEEEEECHHHHHHHHHHHHHHTCCEEEECCCGG-GC---SCTTBCCCSCCH
T ss_pred             HHHHH--------------------hhccEEeeccCChhHHHHHHHHHhcCCceecccccHH-Hc---CCCccccCCCCH
Confidence            33322                    2678888877666666666777888999986543322 11   246778888888


Q NP_000836.2     200 SYQAQAMVDIVTAL----GWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       200 ~~~~~~~~~~l~~~----~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~  275 (908)
                      ...+..+++++.+.    +|++|++++.++.++..+.+.|++.+++. ++++.. ..+.  ....++...+++++. .++
T Consensus       149 ~~~~~~~~~~l~~~~~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~-~~~~--~~~~~~~~~~~~~~~-~~~  223 (405)
T 4N03_A          149 DVDMINGVQWLMDKKLIKKGDKLGHVYFEGDYGGSALRGTKYAAEQL-GLEVFE-LPIK--PTDRDMKSQVAALAK-EKV  223 (405)
T ss_dssp             HHHHHHHHHHHHHTTSSCTTCEEEEEEETTHHHHHHHHHHHHHHHHH-TCEEEE-EEEC--TTCCCCHHHHHHHHH-TTC
T ss_pred             HHHHHHHHHHHHHccccCCCCEEEEEEecCcchhhHHHHHHHHHHHh-CCEEEE-eeeC--CCCCCHHHHHHHHHH-CCC
Confidence            88888888887543    89999999976667777788888888765 355432 2221  122345566677763 578


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQE--EIAEGAVTILPKRASIDGFDRYFRSRTLANN  353 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~--~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~  353 (908)
                      |+|++...+..+..+++++++.|+.  ..|++.+.+...... ....  ....+.+.......         .   ....
T Consensus       224 ~~vv~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~g~~~~~~~~~---------~---~~~~  288 (405)
T 4N03_A          224 DAILLSAGPQQAASLAGIARSQGMK--QPILGSNSAYSPQLL-ATPAKPALVEGFFIATAGAP---------M---SADL  288 (405)
T ss_dssp             SEEEEESCHHHHHHHHHHHHHTTCC--CCEEECTTSCCGGGG-GSTTHHHHSSSEEEEESSCC---------T---TSSC
T ss_pred             CEEEEecCHHHHHHHHHHHHHcCCC--CCEEEecccCCHHHh-cCCCchhhcCCEEEEecCCC---------C---CCCC
Confidence            8887776666677888888887773  456665533221110 0000  11222221111000         0   0001


Q NP_000836.2     354 RRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPR  433 (908)
Q Consensus       354 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~  433 (908)
                      +....|.+.+++.+..                          .....++..+||++++++++++++....          
T Consensus       289 ~~~~~f~~~~~~~~~~--------------------------~~~~~~~~~~yda~~~~~~al~~~~~~~----------  332 (405)
T 4N03_A          289 PAIKKLAEAYSKKYPK--------------------------DPLDSGVVNGYGGASIVVSALEKACANK----------  332 (405)
T ss_dssp             HHHHHHHHHHHHHCTT--------------------------SCCCHHHHHHHHHHHHHHHHHHHHHHTT----------
T ss_pred             HHHHHHHHHHHHHCCC--------------------------CCCChHHHHHHHHHHHHHHHHHHHHHCC----------
Confidence            1112222222222110                          0113457789999999999999875311          


Q NP_000836.2     434 MSTIDGKELLGYIRAV-NF-NGSAGTPVTFNENGDA-PGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       434 ~~~~~~~~l~~~l~~~-~f-~G~~G~~v~Fd~~G~~-~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                        ..+++.+.+.|++. .| .|.+| ++.|+.+|++ ...+.|++++..+ ...++.||.|...
T Consensus       333 --~~~~~~l~~~l~~~~~~~~g~~g-~i~f~~~g~~~~~~~~i~~~~~~~-~~~~~~v~~~~~~  392 (405)
T 4N03_A          333 --DLTREGLINAHRSEANADDGLGT-PMNFTYFDKPATRKTYIIKPDEKA-TGGAVIVEQAFES  392 (405)
T ss_dssp             --EESHHHHHHHHTTCSCBCCSSSC-CBCCSCCSSCSCCCEEEEEECTTS-GGGEEEEEEEECC
T ss_pred             --CCCHHHHHHHHhcccCCCCCCCC-ccccccCCCCCcccEEEEEeCCCC-CCceEEEeeeecc
Confidence              12455677788765 57 68888 8999988876 4578888886432 3468899999765


No 102
>4M88_A Extracellular ligand-binding receptor; STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER; HET: GOL; 1.762A {Verminephrobacter eiseniae}
Probab=99.46  E-value=4.9e-18  Score=180.42  Aligned_cols=343  Identities=14%  Similarity=0.064  Sum_probs=212.0  Template_Neff=12.000

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||++.|.++...          ..+.....|++.|++++|+.+++. |+++++.+.|+.+++..    ..+.+++
T Consensus         2 ~~~i~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~g~~~-g~~i~~~~~d~~~~~~~----~~~~~~~   66 (357)
T 4M88_A            2 NAQIVLGQIGPFTGPLA----------ADAAGLNQGIKAYLAQANKAGGIR-GQKLTLFEADDRFSGEG----FAEQFPK   66 (357)
T ss_dssp             -CEEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHHTTCBT-TBEEEEEEEECTTSHHH----HHHHHHH
T ss_pred             CCeEEEeEEecCCCCCh----------HHhHHHHHHHHHHHHHHHHcCCCC-CEEeEEEEEcCCCCHHH----HHHHHHH
Confidence            46789999999876421          245678899999999999876654 77888888887665432    3333443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVAN--ILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~--~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++.                   ++++++|++.++.....+..  .+...++|+|++....+.+.. ..+++++++.++..
T Consensus        67 ~~~-------------------~~v~~iig~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~-~~~~~~~~~~~~~~  126 (357)
T 4M88_A           67 AME-------------------KKPLALISPMGSAAIKRMLDDKLLDTAPVVVVNGVPGAESLRT-PGHPKFFHVRAGDK  126 (357)
T ss_dssp             HHT-------------------TCCSEEECCBCHHHHHHHHHTTTTSSCSCEEECCBSCCHHHHS-SCCTTEEBCSCCHH
T ss_pred             HHh-------------------hCCCEEEeCCCcHHHHHHcchhHHhcCCcEEEECCCCchhhcC-CCCCCeEEccCCcH
Confidence            332                   47889998877666555555  678889999988765544332 23577899999998


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISRE-IGGVCIAQ-SQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~-~~~i~v~~-~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ..++.+++++.+.+|+++++++.++.++..+.+.|++.+++ . ++.+.. ...+.  .+..+....+++++. .++|+|
T Consensus       127 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~-g~~i~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i  202 (357)
T 4M88_A          127 QEIEEIVSHAQMLGMSKLATLYQDLPTGTSGMAVVQEAVKTVP-GGKIELNGVKSG--PDAAALAAAARQIAA-LGAQGV  202 (357)
T ss_dssp             HHHHHHHHHHHHTTCSEEEEEEESSHHHHHHHHHHHHHHHTCT-TCCCEEEEEEEC--SSHHHHHHHHHHHHT-TTCSEE
T ss_pred             HHHHHHHHHHHHhCCCEEEEEEeCChhcHHHHHHHHHHHHcCC-CCceEEEEeecC--CCHHHHHHHHHHHHH-cCCCEE
Confidence            88999999988889999999997667787888888888776 4 344431 11111  122345556666663 578888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQE-EIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~-~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      ++...+..+..+++++++.|+.  ..|++.+.+...... .... ....+.+.......        ..   ....+...
T Consensus       203 i~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~--------~~---~~~~~~~~  268 (357)
T 4M88_A          203 LVIGPPPFIVAGIAALRKADVT--QPLFVLSYVSAAQIV-KVVGVAGARGVGIVQAFPD--------PN---DKMLPVQR  268 (357)
T ss_dssp             EEESSHHHHHHHHHHHHHTTCC--SCEEECTTCCHHHHH-HHHHHHHHTTEEEEESSSC--------TT---CCSSHHHH
T ss_pred             EEECCHHHHHHHHHHHHhCCCC--CCEEEeecCCHHHHH-HHHcccCcceEEEEEEeCC--------cc---cCCCHHHH
Confidence            7777666677888998888874  345554433221110 0000 11122221110000        00   00011122


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTI  437 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~  437 (908)
                      .|.+.+++.++.                         ...+..++..+||+++++++|++++...             ..
T Consensus       269 ~f~~~~~~~~~~-------------------------~~~~~~~~~~~yda~~~~~~al~~~~~~-------------~~  310 (357)
T 4M88_A          269 EFQAAMKEAFPQ-------------------------MQEYTEFQLEGYLSARTVGEALKHPKNT-------------GL  310 (357)
T ss_dssp             HHHHHHHHHCTT-------------------------CCSCCHHHHHHHHHHHHHHHHHHSTTCC-------------CS
T ss_pred             HHHHHHHHHccc-------------------------cCCCChHHHHHHHHHHHHHHHHhccCCC-------------CC
Confidence            233333322210                         0112346788999999999999886421             12


Q NP_000836.2     438 DGKELLGYIRAV-NFNGSAGTPVTFNENGDAPGRYDIFQYQ  477 (908)
Q Consensus       438 ~~~~l~~~l~~~-~f~G~~G~~v~Fd~~G~~~~~~~i~~~~  477 (908)
                      +++.+.++|++. .|. .+|.++.|+++|++...+.+.++.
T Consensus       311 ~~~~l~~~l~~~~~~~-~~G~~~~f~~~~~~~~~~~i~~~~  350 (357)
T 4M88_A          311 SAANLAATLSTMGEID-IGGFHLDFSKGNAGSRYVNIGVIG  350 (357)
T ss_dssp             SHHHHHHHHHHSCCEE-ETTEEECCSSSSBCCCCCEEEEEC
T ss_pred             CHHHHHHHHHcCCCcc-cCcEEeecCCCCCccCcEEEEEEc
Confidence            455677778765 465 334268999877766677777774


No 103
>3I09_B Periplasmic branched-chain amino acid-binding protein; TYPE I PERIPLASMIC BINDING PROTEIN; HET: MSE, CIT, EDO, AAE; 1.8A {Burkholderia mallei}
Probab=99.45  E-value=6.2e-18  Score=181.03  Aligned_cols=347  Identities=10%  Similarity=0.101  Sum_probs=213.9  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||+++|.++...         ...+.....+++.|++++|.  + +.|+++++.+.|+.+++.    ...+.+++
T Consensus         2 ~~~~~Ig~i~~~~~~~~---------~~~~~~~~~g~~~a~~~~~~--~-~~g~~i~~~~~d~~~~~~----~~~~~~~~   65 (375)
T 3I09_B            2 ADSVKIGFITDMSGLYA---------DIDGQGGLEAIKMAVADFGG--K-VNGKPIEVVYADHQNKAD----IAASKARE   65 (375)
T ss_dssp             CSSEEEEEEECSSSTTT---------TTSHHHHHHHHHHHHHHHTS--E-ETTEEEEEEEEECTTCHH----HHHHHHHH
T ss_pred             CCeeEEEEEeCCCCcch---------hhcchhHHHHHHHHHHHhCC--c-cCCEEEEEEEecCCCCHH----HHHHHHHH
Confidence            46789999999875421         01356778899999999872  2 346778888888765533    22333444


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                  .++++++|++.++.....+...+...++|+|.+....+.+.....+++++++.+++...
T Consensus        66 l~~------------------~~~v~~vi~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~  127 (375)
T 3I09_B           66 WMD------------------RGGLDLLVGGTNSATALSMNQVAAEKKKVYINIGAGADTLTNEQCTPYTVHYAYDTMAL  127 (375)
T ss_dssp             HHH------------------HSCEEEEEECSCHHHHHHHHHHHHHHTCEEEECSCCCGGGGTTTCCTTEEECSCCHHHH
T ss_pred             HHH------------------hCCCCEEEecCChHHHHHHHHHHHHcCCEEEEccCCccccCCCcCCCceeEecCCHhHH
Confidence            332                  15788999977766666667778889999999876655433222346778888888888


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      ++.+++++.+.+|+++++++.++.++..+.+.+.+.+++. ++++.....+.  .+..++...++++.. .++|++++..
T Consensus       128 ~~~~~~~l~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~~~  203 (375)
T 3I09_B          128 AKGTGSAVVKQGGKTWFFLTADYAFGKALEKNTADVVKAN-GGKVLGEVRHP--LSASDFSSFLLQAQS-SKAQILGLAN  203 (375)
T ss_dssp             CCCCCHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCSCCHHHHHHHHH-TTCSEEEEEC
T ss_pred             HHHHHHHHHHcCCCEEEEEEeCcHHHHHHHHHHHHHHHHC-CCEEEEEEeCC--CCccchHHHHHHHHh-cCCCEEEEEe
Confidence            8899998877899999999976667778888888888775 35544322222  122345556666653 4788887776


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQ-EEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAE  361 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~-~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  361 (908)
                      .+..+..+++++++.|+...+ ++..........  ... .....+.+....          +..    ...+....|.+
T Consensus       204 ~~~~~~~~~~~l~~~g~~~~~-~~~~~~~~~~~~--~~~~~~~~~~~~~~~~----------~~~----~~~~~~~~f~~  266 (375)
T 3I09_B          204 AGGDTVNAIKAAKEFGITKTM-KLAALLMFINDV--HALGLETTQGLVLTDS----------WYW----NRDQASRQWAQ  266 (375)
T ss_dssp             CHHHHHHHHHHHHHTTGGGTC-EEEESSCCHHHH--HHHCHHHHTTCEEEES----------CCT----TSSHHHHHHHH
T ss_pred             cchHHHHHHHHHHHcCCCCCe-eEeeccccHHHH--HHcCHhHHcCceEeec----------ccc----CCCHHHHHHHH
Confidence            666778899999888875322 232211111000  000 011122211110          000    00111122333


Q NP_000836.2     362 FWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKE  441 (908)
Q Consensus       362 ~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~  441 (908)
                      .+++.++                           ..++.++..+|||++++++|++++..               .++..
T Consensus       267 ~~~~~~~---------------------------~~p~~~~~~~yda~~~~~~al~~~~~---------------~~~~~  304 (375)
T 3I09_B          267 RYFAKMK---------------------------KMPSSLQAADYSSVTTYLKAVQAAGS---------------TDSDK  304 (375)
T ss_dssp             HHHHHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHTS---------------CCHHH
T ss_pred             HHHHHHC---------------------------CCCCHHHHHHHHHHHHHHHHHHHhCC---------------CCHHH
Confidence            2322221                           11235677899999999999988642               13456


Q NP_000836.2     442 LLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       442 l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      +.++|++..|.|.+| .+.|+.+|++...+.+.+++.+    . ..+|.|.
T Consensus       305 ~~~~l~~~~~~~~~~-~~~~~~~g~~~~~~~i~~~~~~----~-~~~~~~~  349 (375)
T 3I09_B          305 VMAQLKKMKIDDFYA-KGYIRTDGSMIHDMYLMEVKKP----S-ESKEPWD  349 (375)
T ss_dssp             HHHHHTTSCEESSSC-EEEECTTSBEECCEEEEEECCG----G-GCCSTTC
T ss_pred             HHHHHhcCCccccCC-ceEEecCCCeEeeEEEEEEeCC----C-CCCCCcc
Confidence            778888777877555 6777777877777888887631    1 4555565


No 104
>5TQ0_B NMDA glutamate receptor subunit, Glutamate; ION CHANNEL, NMDA RECEPTOR, ALLOSTERIC; HET: GOL, NAG, SO4; 2.7A {Mus musculus}
Probab=99.45  E-value=6.5e-18  Score=179.74  Aligned_cols=343  Identities=16%  Similarity=0.212  Sum_probs=207.3  Template_Neff=11.700

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVR---ILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~---~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ++||+++|.++..                   +.+.|++++|+.  .++|+++++.   +.|+.+++..+.    +.+++
T Consensus         1 i~ig~i~~~sg~~-------------------~~~~~~~~~n~~--~~~~~~v~l~~~~~~d~~~~~~~~~----~~~~~   55 (360)
T 5TQ0_B            1 LNIAVLLGHSHDV-------------------TERELRNLWGPE--QATGLPLDVNVVALLMNRTDPKSLI----THVCD   55 (360)
T ss_dssp             CEEEEEECSSSCC-------------------CCCCC--------------CSCCEEEEEECSCCSHHHHH----HHHHH
T ss_pred             CeEEEEecCCCCh-------------------hHHHHHHccCcc--ccCCCCcEEEEEEeecCCCCHHHHH----HHHHH
Confidence            5799999987631                   235577788864  2457777774   477766644333    33333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKI-SGVIGAAASSVS--IMVANILRLFKIPQISYASTAPELSD-NTRYDFFSRVVPP  198 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v-~~vIg~~~s~~~--~~va~~~~~~~iP~Is~~~~~~~l~~-~~~~~~~~~~~~~  198 (908)
                      ++..                  +++ ++++|+.++..+  ..++.++...++|+|++.+..+.+.. ...+++++++.|+
T Consensus        56 l~~~------------------~~v~~~vig~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~  117 (360)
T 5TQ0_B           56 LMSG------------------ARIHGLVFGDDTDQEAVAQMLDFISSQTFIPILGIHGGASMIMADKDPTSTFFQFGAS  117 (360)
T ss_dssp             HHHT------------------TCCSEEEEECCSCCTHHHHHHHHHHHHHCCCEEEEEGGGGCCCSCCCTTCCEEESCCC
T ss_pred             HHcC------------------CCceEEEEcCCCChHHHHHHHHHHHhhcCCCEEEecCCCcccccCCCCCCceEeecCC
Confidence            3321                  456 678898877665  67788889999999998876654432 2247899999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ...+++++++++.+++|+++++++.++.++....+.+++.+++.+ ++++.....++  ....++. .+++++. .++++
T Consensus       118 ~~~~~~~l~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~~~~~--~~~~~~~-~~~~i~~-~~~~~  193 (360)
T 5TQ0_B          118 IQQQATVMLKIMQDYDWHVFSLVTTIFPGYRDFISFIKTTVDNSFVGWDMQNVITLD--TSFEDAK-TQVQLKK-IHSSV  193 (360)
T ss_dssp             HHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHSSSCCEECCCEEES--CSSCTHH-HHHHHTT-CCCSE
T ss_pred             HHHHHHHHHHHHHHcCCeEEEEEEecCCchHHHHHHHHHHHhcCCCcceeEEEEEec--CCcccHH-HHHHHhc-CCCeE
Confidence            988899999999888999999999887788877788887776542 13443322232  1223455 6666663 57888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      |++.........+++++++.|+.. .+.|+..+.+......  .......+.+.                          
T Consensus       194 vv~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~~--------------------------  245 (360)
T 5TQ0_B          194 ILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTEL--IPKEFPSGLIS--------------------------  245 (360)
T ss_dssp             EEEECCHHHHHHHHHHHHHTTCSSTTSEEEECHHHHCSTTC--CCTTSCTTCEE--------------------------
T ss_pred             EEEEcCHHHHHHHHHHHHHcCCCCCCEEEEeecccCCCCcC--CCccCCCceEE--------------------------
Confidence            888777777888999988888753 3567765433221100  00000001000                          


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP--GYIGLCPRM  434 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~--~~~~~~~~~  434 (908)
                        + . +. .+                              ...++..+|||++++++|++++....+.  .....|...
T Consensus       246 --~-~-~~-~~------------------------------~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~c~~~  290 (360)
T 5TQ0_B          246 --V-S-YD-DW------------------------------DYSLEARVRDGLGILTTAASSMLEKFSYIPEAKASCYGQ  290 (360)
T ss_dssp             --E-E-SC-CS------------------------------SSCHHHHHHHHHHHHHHHHHHHHHHSSSCCCCCSCSSCC
T ss_pred             --E-E-ec-Cc------------------------------cccHHHHHHHHHHHHHHHHHHHHHhcCCCCccccccccc
Confidence              0 0 00 00                              0124567999999999999987543210  001223211


Q NP_000836.2     435 ---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 ---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                         ....+..+.+.|++..|.|.   .+.||++|++. ..+.+++++.   ...++.||.|+... +....+.|+
T Consensus       291 ~~~~~~~~~~l~~~l~~~~~~G~---~i~f~~~g~~~~~~~~i~~~~~---~~~~~~vg~w~~~~-l~~~~~~w~  358 (360)
T 5TQ0_B          291 AEKPETPLHTLHQFMVNVTWDGK---DLSFTEEGYQVHPRLVVIVLNK---DREWEKVGKWENQT-LSLRHAVWP  358 (360)
T ss_dssp             -----CCSCCSTTTSSSCEETTE---ECCBCTTSSBSSCCCEEEEECT---TSCEEEEEECTTTT-CCBCCC---
T ss_pred             CCCCCChHHHHHHHHcceeEcCe---eeEECCCCceeceEEEEEEeeC---CCceEEEEEEECCe-eEecceecC
Confidence               11245567788888888875   69999999885 6788888873   15789999998762 322335563


No 105
>5TPW_B NMDA glutamate receptor subunit, Glutamate; ION CHANNEL, NMDA RECEPTOR, ALLOSTERIC; HET: NAG, GOL, SO4; 2.909A {Mus musculus}
Probab=99.45  E-value=6.5e-18  Score=179.74  Aligned_cols=343  Identities=16%  Similarity=0.212  Sum_probs=203.3  Template_Neff=11.700

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVR---ILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~---~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ++||+++|.++..                   +.+.|++++|+.  .++|+++++.   +.|+.+++..+.    +.+++
T Consensus         1 i~ig~i~~~sg~~-------------------~~~~~~~~~n~~--~~~~~~v~l~~~~~~d~~~~~~~~~----~~~~~   55 (360)
T 5TPW_B            1 LNIAVLLGHSHDV-------------------TERELRNLWGPE--QATGLPLDVNVVALLMNRTDPKSLI----THVCD   55 (360)
T ss_dssp             CEEEEEECSTTCC-------------------CC-------------------CCEEEEEECCCCSHHHHH----HHHHH
T ss_pred             CeEEEEecCCCCh-------------------hHHHHHHccCcc--ccCCCCcEEEEEEeecCCCCHHHHH----HHHHH
Confidence            5799999987631                   235577788864  2457777774   477766644333    33333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKI-SGVIGAAASSVS--IMVANILRLFKIPQISYASTAPELSD-NTRYDFFSRVVPP  198 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v-~~vIg~~~s~~~--~~va~~~~~~~iP~Is~~~~~~~l~~-~~~~~~~~~~~~~  198 (908)
                      ++..                  +++ ++++|+.++..+  ..++.++...++|+|++.+..+.+.. ...+++++++.|+
T Consensus        56 l~~~------------------~~v~~~vig~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~  117 (360)
T 5TPW_B           56 LMSG------------------ARIHGLVFGDDTDQEAVAQMLDFISSQTFIPILGIHGGASMIMADKDPTSTFFQFGAS  117 (360)
T ss_dssp             HHTT------------------SCCSEEEEECSSCCTHHHHHHHHHHHHHCCCEEEEEGGGGCCCSCCCTTCCEEESCCC
T ss_pred             HHcC------------------CCceEEEEcCCCChHHHHHHHHHHHhhcCCCEEEecCCCcccccCCCCCCceEeecCC
Confidence            3321                  456 678898877665  67788889999999998876654432 2247899999999


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ...+++++++++.+++|+++++++.++.++....+.+++.+++.+ ++++.....++  ....++. .+++++. .++++
T Consensus       118 ~~~~~~~l~~~~~~~~~~~v~iv~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~~~~~--~~~~~~~-~~~~i~~-~~~~~  193 (360)
T 5TPW_B          118 IQQQATVMLKIMQDYDWHVFSLVTTIFPGYRDFISFIKTTVDNSFVGWDMQNVITLD--TSFEDAK-TQVQLKK-IHSSV  193 (360)
T ss_dssp             HHHHHHHHHHHHHHTTCCEEEEEECSSTTHHHHHHHHHHHHHTSTTCSEECCCEECC--TTSCHHH-HHHHHTT-CCCSE
T ss_pred             HHHHHHHHHHHHHHcCCeEEEEEEecCCchHHHHHHHHHHHhcCCCcceeEEEEEec--CCcccHH-HHHHHhc-CCCeE
Confidence            988899999999888999999999887788877788887776542 13443322232  1223455 6666663 57888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      |++.........+++++++.|+.. .+.|+..+.+......  .......+.+.                          
T Consensus       194 vv~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~~--------------------------  245 (360)
T 5TPW_B          194 ILLYCSKDEAVLILSEARSLGLTGYDFFWIVPSLVSGNTEL--IPKEFPSGLIS--------------------------  245 (360)
T ss_dssp             EEEESCHHHHHHHHHHHHHTTCSSTTSEEEECHHHHCCSSC--CCTTSCTTCEE--------------------------
T ss_pred             EEEEcCHHHHHHHHHHHHHcCCCCCCEEEEeecccCCCCcC--CCccCCCceEE--------------------------
Confidence            888777777888999988888753 3567765433221100  00000001000                          


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP--GYIGLCPRM  434 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~--~~~~~~~~~  434 (908)
                        + . +. .+                              ...++..+|||++++++|++++....+.  .....|...
T Consensus       246 --~-~-~~-~~------------------------------~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~c~~~  290 (360)
T 5TPW_B          246 --V-S-YD-DW------------------------------DYSLEARVRDGLGILTTAASSMLEKFSYIPEAKASCYGQ  290 (360)
T ss_dssp             --E-E-SC-CT------------------------------TSCHHHHHHHHHHHHHHHHHHTTTSSSSCCCCCSCSCC-
T ss_pred             --E-E-ec-Cc------------------------------cccHHHHHHHHHHHHHHHHHHHHHhcCCCCccccccccc
Confidence              0 0 00 00                              0124567999999999999987543210  001223211


Q NP_000836.2     435 ---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLHLKVEDMQWA  505 (908)
Q Consensus       435 ---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~~~~~~i~w~  505 (908)
                         ....+..+.+.|++..|.|.   .+.||++|++. ..+.+++++.   ...++.||.|+... +....+.|+
T Consensus       291 ~~~~~~~~~~l~~~l~~~~~~G~---~i~f~~~g~~~~~~~~i~~~~~---~~~~~~vg~w~~~~-l~~~~~~w~  358 (360)
T 5TPW_B          291 AEKPETPLHTLHQFMVNVTWDGK---DLSFTEEGYQVHPRLVVIVLNK---DREWEKVGKWENQT-LSLRHAVWP  358 (360)
T ss_dssp             -----CCSCCSSTTTSSCEETTE---ECCBCTTSSBSSCCCEEEEEET---TTEEEEEEECTTTT-CCCCC----
T ss_pred             CCCCCChHHHHHHHHcceeEcCe---eeEECCCCceeceEEEEEEeeC---CCceEEEEEEECCe-eEecceecC
Confidence               11245567788888888875   69999999885 6788888873   15789999998762 322335563


No 106
>4MAA_A Putative branched-chain amino acid ABC; Psi-Biology, MCSG, Midwest Center For; HET: GOL; 2.0A {Pseudomonas protegens}
Probab=99.44  E-value=9.1e-18  Score=181.66  Aligned_cols=352  Identities=13%  Similarity=0.078  Sum_probs=215.8  Template_Neff=12.000

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.++...          ..+.....|++.|++++|..    .|.++++.+.|+.+++..    ..+.
T Consensus        29 ~~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~~~----~g~~i~~~~~d~~~~~~~----~~~~   90 (403)
T 4MAA_A           29 AFAAEPFTFYGLKSMSGAFA----------SYGKFADMGSRLAVEQYPTL----LGRPLHYKVIDTEGNAGK----AVRR   90 (403)
T ss_dssp             -CCCCCEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHTCSEE----TTEEEEEEEEECTTCHHH----HHHH
T ss_pred             hhhCCCEEEEEEecCCCCch----------hhhHHHHHHHHHHHHhcCcc----CCeeeEEEEEeCCCCHHH----HHHH
Confidence            45678999999999875321          25667889999999999842    366788888887655432    3333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV-PP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~-~~  198 (908)
                      +++++.                  .++++++|++.++.....+...+...++|+|.+.. .+.+.....+++++++. ++
T Consensus        91 ~~~l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~-~~~~~~~~~~~~~~~~~~~~  151 (403)
T 4MAA_A           91 VQEAIA------------------QDGARFFQGCTLSSSALAVAKEVGKVGGVFMTPVG-ADEITGKDCNASTFRWSVPT  151 (403)
T ss_dssp             HHHHHH------------------HHCCCEEEECSSHHHHHHHHHHHHHHTCEEEECCC-CGGGGTTTCCTTEEECSCCH
T ss_pred             HHHHHH------------------hcCCCEEEecCCcHHHHHHHHHHHhhCCEEEccCC-ccccCCCCCCCceeEeeCCc
Confidence            444332                  15788999987776666777778889999998875 33222211256777875 66


Q NP_000836.2     199 DSYQAQAMVDIVTA-LGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       199 ~~~~~~~~~~~l~~-~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ....++.+++++.+ .+|++|++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++|+
T Consensus       152 ~~~~~~~~~~~l~~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~d~  227 (403)
T 4MAA_A          152 YGAIRETMVPLIKLLPEAKRWYTITPQYVFGEALLEGAKQVCAEH-GIEHIGNSYHS--LQEQEFSGYLTNAIA-ARPDV  227 (403)
T ss_dssp             HHHHHHHHHHHHHHCTTCCEEEEEEESSHHHHHHHHHHHHHHHHH-TCEEEEEEEEC--TTCCCCHHHHHHHHH-HCCSE
T ss_pred             HHHHHHhhHHHHHhCCCCCEEEEEEeCCHHHHHHHHHHHHHHHHC-CCEEEEEEEec--CCCCChHHHHHHHHH-hCCCE
Confidence            66677788888866 589999999976677778888888888765 35544332222  122345556666653 57888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNV  357 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  357 (908)
                      +++...+..+..+++++++.|+..++.+++.+....... .........+.+.....          +..   ...+...
T Consensus       228 v~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~~~---~~~~~~~  293 (403)
T 4MAA_A          228 LVLLNFGSQSSNALRQAVNFGIKERMKVLLVWSAGLDQF-QELGSDVLEGVYLGAQY----------WHQ---VDTPLNR  293 (403)
T ss_dssp             EEECCCHHHHHHHHHHHHHHTHHHHSEEEESSCCTHHHH-HHHHHHHHBTCEEEESC----------CTT---CCCHHHH
T ss_pred             EEEECCchHHHHHHHHHHHCCCccCcEEEEeccccHHHH-HHHchhhhcCcEEEecc----------ccc---CCCHHHH
Confidence            877765566778888888888753333444322111100 00000112222211100          000   0011112


Q NP_000836.2     358 WFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTI  437 (908)
Q Consensus       358 ~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~  437 (908)
                      .|.+.+++.++                           ..++.++..+||++++++++++++..               .
T Consensus       294 ~f~~~~~~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~---------------~  331 (403)
T 4MAA_A          294 ELVKLTQAKYG---------------------------INPTYPLAADYIGSKIILDTIAATGS---------------F  331 (403)
T ss_dssp             HHHHHHHHHTS---------------------------SCCCHHHHHHHHHHHHHHHHHHHHTC---------------C
T ss_pred             HHHHHHHHHHC---------------------------CCCChhHHHHHHHHHHHHHHHHHHCC---------------C
Confidence            23333322221                           11234567899999999999988642               2


Q NP_000836.2     438 DGKELLGYIRAVNFNGSAGTPVTFNE-NGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       438 ~~~~l~~~l~~~~f~G~~G~~v~Fd~-~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ++..+.++|++..|.|.+| .+.||+ +++....+.+++++.    .. ..+|.|+..
T Consensus       332 ~~~~l~~~l~~~~~~g~~g-~~~f~~~~~~~~~~~~i~~~~~----~~-~~~~~w~~~  383 (403)
T 4MAA_A          332 DGATVAKAMQGLTYQGPTG-EESIRAGDHQVIKDYYLLVGKA----AA-TMRDKDDLA  383 (403)
T ss_dssp             CHHHHHHHHTTCEEEETTE-EEEECTTTCBEECCEEEEEECC----GG-GCSSTTCCE
T ss_pred             CHHHHHHHHcCCceecCCe-eEEeCCCCCeeeeeEEEEEeec----cc-ccCCHhHHH
Confidence            3456778888888999988 899997 334445677777762    22 567888755


No 107
>5L1B_D Glutamate receptor 2; Transporter, fusion protein, MEMBRANE PROTEIN; HET: NAG; 4.0A {Rattus norvegicus}
Probab=99.43  E-value=1.1e-17  Score=198.82  Aligned_cols=356  Identities=15%  Similarity=0.203  Sum_probs=224.6  Template_Neff=11.600

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~~~~  122 (908)
                      ++++||++.|.++.                ....|++.|++++|++     |+++++.+.|+. +++.    .+.+.+++
T Consensus         1 ~~i~Ig~~~~~~~~----------------~~~~g~~~a~~~in~~-----g~~i~~~~~d~~~~~~~----~~~~~~~~   55 (803)
T 5L1B_D            1 NSIQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSF----AVTNAFCS   55 (803)
T ss_dssp             CEEEEEEEEESSCS----------------HHHHHHHHHHHHTCCS-----SCEEEEEEEEECTTCHH----HHHHHHHH
T ss_pred             CceeeEeeeCCCCh----------------HHHHHHHHHHHhhcCC-----CceeeeeeEecCCCCHH----HHHHHHHH
Confidence            36889999998752                4668999999999975     467888888865 3332    22233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      +..                   +++++++|+.++..+..++.++...++|++++..+++     ..+++++++.++   .
T Consensus        56 l~~-------------------~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~---~  108 (803)
T 5L1B_D           56 QFS-------------------RGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPD---L  108 (803)
T ss_dssp             HHH-------------------TTCSEEECCCCTTTHHHHHHHHHHSCCEEEECSCCCS-----SCCSSEEECSCC---C
T ss_pred             HHh-------------------cCeeEEEecCChHHHHHHHHHHcccCCcEEeCCCCCC-----CCCCeEEEecCC---h
Confidence            332                   5789999998887777888888899999998876443     247889999988   5


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPR--EPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ++++++++++++|+++++++ +++++....+.+.+.+++. ++++.....++.  +.+..++...++++++ .++++|++
T Consensus       109 ~~~~~~~l~~~~~~~v~ii~-~~~~~~~~~~~~~~~~~~~-~~~i~~~~~~~~~~~~~~~d~~~~~~~i~~-~~~~~i~~  185 (803)
T 5L1B_D          109 KGALLSLIEYYQWDKFAYLY-DSDRGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKERRVIL  185 (803)
T ss_dssp             HHHHHHHHHHTTCSEEEEEE-CSTTCSHHHHHHHHHHHHH-TCEEEEEECSCCCSSSHHHHHHHHHHHHGG-GTCCCEEE
T ss_pred             HHHHHHHHHHhCCCEEEEEE-eCcchHHHHHHHHHHHhhc-CCeEEEEEccCCCCCCCcchhHHHHHHHHh-cCCeEEEE
Confidence            77888888888999999999 5567777777777777664 355544322210  0122456677777763 57899888


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      .+....+..+++++++.|+.. .+.|++.+.+...... ........+......           ..    ...+....+
T Consensus       186 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~-----------~~----~~~~~~~~f  249 (803)
T 5L1B_D          186 DCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGAEVSGFQI-----------VD----YDDSLVSKF  249 (803)
T ss_dssp             ESCHHHHHHHHHHHHHTTCCBTTCEEEECSSBTTTSCC-SSSSSSBCEEEEEEC-----------SC----SSSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHcCCCCCCcEEEEEeCCCCccch-hhcccCCeeEEEEEE-----------Ee----CCchHHHHH
Confidence            877777888999999888754 3567765432211100 000000111111100           00    011112233


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~~~~-  434 (908)
                      .+.+++.+++.             +...      ....+..++..+|||++++++|++++......    .....|... 
T Consensus       250 ~~~~~~~~~~~-------------~~~~------~~~~~~~~~~~~yda~~~~a~al~~~~~~~~~~~~~~~~~~~~~~~  310 (803)
T 5L1B_D          250 IERWSTLEEKE-------------YPGA------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANP  310 (803)
T ss_dssp             HHHHTTSCTTT-------------STTC------SSSCCCHHHHHHHHHHHHHHHHHHHHHHTTCCCCCSSCCCCTTCSS
T ss_pred             HHHHHhcchhh-------------CCCc------ccCCCchHHHHHHHHHHHHHHHHHHHHHhccccccCCCCCCcccCC
Confidence            33343332210             0000      00123456788999999999999988653210    000122110 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                        ...+++.+.+.|++..|.|.+| ++.|+++|++.. .+.+++++    ++.++.+|.|+..
T Consensus       311 ~~~~~~~~~l~~~l~~~~~~g~~G-~i~f~~~g~~~~~~~~i~~~~----~~~~~~~~~~~~~  368 (803)
T 5L1B_D          311 AVPWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEV  368 (803)
T ss_dssp             CCCCTHHHHHHHHHTTCCCEETTE-ECEECSSCCEESCCEEEEEEC----SSSEEEEEEEETT
T ss_pred             CCCccccHHHHHHHHhcCccCCCc-cEEECCCCcEEEEEEEEEEec----cCCceEEEEEecC
Confidence              1124567888888889999988 899999898764 78888887    2467888888854


No 108
>4TLL_D GluN1/GluN2B; Neurotransmitter receptor, NMDA receptor, GluN1/GluN2B; HET: QEM, JEG, NAG; 3.59A {Xenopus laevis}
Probab=99.42  E-value=1.3e-17  Score=198.99  Aligned_cols=340  Identities=15%  Similarity=0.200  Sum_probs=214.1  Template_Neff=11.400

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPD--LLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~--il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ...+++++||+++|.++              .        ++|++++|++++  ++++..+.+...|+.+++..+.+.  
T Consensus         5 ~~~~~~i~Ig~~~p~sg--------------~--------~~a~~~~n~~~~~~~~~~~~~~~~~~d~~~~~~~~~~~--   60 (824)
T 4TLL_D            5 AQKHPNMDIAVILVGTT--------------E--------EVAIKDVHEKDDFHHLPVTPRVELVTMQESDPKSIITR--   60 (824)
T ss_dssp             ---CCEEEEEEEEECCS--------------S--------CCCTTC-------CCCSSEEEEEEEEESCCCHHHHHHH--
T ss_pred             cccCCCceEEEEEcCCC--------------h--------HHhhhccccCCCcccCCCCceeEEEeCCCCCHHHHHHH--
Confidence            45567899999999763              1        889999998876  455665667777777665443333  


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVI-GAAASS--VSIMVANILRLFKIPQISYASTAPE-LSDNTRYDFFS  193 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~--~~~~va~~~~~~~iP~Is~~~~~~~-l~~~~~~~~~~  193 (908)
                        +.+++.                  ++++++++ |+.++.  ....++..+...++|++++....+. +++...+++++
T Consensus        61 --~~~l~~------------------~~~v~~vv~G~~~s~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~  120 (824)
T 4TLL_D           61 --ICDLMS------------------DKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIMADKEEASMFF  120 (824)
T ss_dssp             --HHHHHT------------------TTCEEEEEEECCCCCTHHHHHHHHHHHHHTCCEEECSGGGGSCCSCCCTTCCEE
T ss_pred             --HHHHhc------------------cCCCEEEEEcCCCChHHHHHHHHHHHHhhCCCEEEecCCCccccccccccceEE
Confidence              333332                  15789987 988776  4456677778899999986554432 22233578999


Q NP_000836.2     194 RVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREP-RPGEFEKIIKRLLET  272 (908)
Q Consensus       194 ~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~  272 (908)
                      ++.+++..+++++++++++++|+++++++.+++++....+.+++.+++. ++++.......... ...+....++++++ 
T Consensus       121 ~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~~~-  198 (824)
T 4TLL_D          121 QFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENKVRSTIENS-FVGWELEEVIHLDMSLDDIDSKIQNQLCK-  198 (824)
T ss_dssp             ESSBCHHHHHHHHHHHHHHTTCCEEEEEEESSTTHHHHHHHHHHHHHHC-CBCCEEEEEEEECTTSCCSSCHHHHHHTT-
T ss_pred             ecCCCHHHHHHHHHHHHHHcCCeEEEEEEEcCCChHHHHHHHHHHHHhc-cCCcEEEEEEEecCChhhhhHHHHHHHHh-
Confidence            9999999999999999988899999999988888888888888877764 34433221111101 11223444555653 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLA  351 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~  351 (908)
                      .++|+|++......+..+++++++.|+.+ .+.|+..+.|......  .......+.+                      
T Consensus       199 ~~~~~iv~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~----------------------  254 (824)
T 4TLL_D          199 LQSPVILLYCTKEEATYIFEVAHSVGLTGYGFTWIVPSLVAGDTDT--VPDEFPTGLI----------------------  254 (824)
T ss_dssp             CCSSEEEEECCHHHHHHHHHHHHHHTTTSTTCEEECCTTTCCCSSC--CCTTSCTTCE----------------------
T ss_pred             cCCCEEEEECCHHHHHHHHHHHHHcCCCCCCeEEEeeccCCCCCCC--CCCcCCCCee----------------------
Confidence            57899888877777888999999888754 4567765533221100  0000000000                      


Q NP_000836.2     352 NNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG--YIG  429 (908)
Q Consensus       352 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~--~~~  429 (908)
                                  ...+.                           ..+..+++.+|||++++++|+++.....+..  ...
T Consensus       255 ------------~~~~~---------------------------~~~~~~~~~~Ydav~ll~~a~~~~~~~~~~~~~~~~  295 (824)
T 4TLL_D          255 ------------SVSYD---------------------------EWDYDLPARVRDGIAIITTAASTMLSEHNSIPQSKS  295 (824)
T ss_dssp             ------------EEEEC---------------------------SSSSCHHHHHHHHHHHHHHHHHHHHHHSCC---CCC
T ss_pred             ------------EEEee---------------------------cCCCCcchhHHHHHHHHHHHHHHHHHhcCCCCCCcc
Confidence                        00000                           0112356789999999999999886542210  011


Q NP_000836.2     430 LCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDA-PGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       430 ~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~-~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .|...   ...++..+.+++++.+|.|  | ++.||++|++ ...+.+++++.   ++.++.+|.|+..
T Consensus       296 ~~~~~~~~~~~~~~~l~~~l~~~~f~g--G-~~~f~~~g~~~~~~~~i~~~~~---~g~~~~v~~~~~~  358 (824)
T 4TLL_D          296 SCNNIQESRVYEAHMLKRYLINVTFEG--R-DLSFSEDGYQMHPKLVIILLNQ---ERKWERVGKYKDR  358 (824)
T ss_dssp             CSSCCTTCCHHHHHHHHHHHHCCEETT--E-ECCBCTTSSBSSCCEEEEEECT---TSCEEEEEEECSS
T ss_pred             cccccccccceeHHHHHHHHhcCccCC--c-eeeeCCCCccceeeEEEEEecC---CcceEEEEEEECc
Confidence            22211   1124567888888889988  7 8999999987 46788888873   3578899998764


No 109
>4TLM_D GluN1/GluN2B; neurotransmitter receptor, NMDA receptor, GluN1/GluN2B; HET: NAG, QEM, JEG; 3.77A {Xenopus laevis}
Probab=99.42  E-value=1.3e-17  Score=198.99  Aligned_cols=340  Identities=15%  Similarity=0.200  Sum_probs=216.8  Template_Neff=11.400

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPD--LLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~--il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ...+++++||+++|.++              .        ++|++++|++++  ++++..+.+...|+.+++..+.+.  
T Consensus         5 ~~~~~~i~Ig~~~p~sg--------------~--------~~a~~~~n~~~~~~~~~~~~~~~~~~d~~~~~~~~~~~--   60 (824)
T 4TLM_D            5 AQKHPNMDIAVILVGTT--------------E--------EVAIKDVHEKDDFHHLPVTPRVELVTMQESDPKSIITR--   60 (824)
T ss_dssp             ------CEEEEEEECTT--------------C--------CCTHHHHHHTTTTTTSSSCCEEEEEEESSCCHHHHHHH--
T ss_pred             cccCCCceEEEEEcCCC--------------h--------HHhhhccccCCCcccCCCCceeEEEeCCCCCHHHHHHH--
Confidence            45567899999999763              1        889999998876  455665667777777665443333  


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVI-GAAASS--VSIMVANILRLFKIPQISYASTAPE-LSDNTRYDFFS  193 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~--~~~~va~~~~~~~iP~Is~~~~~~~-l~~~~~~~~~~  193 (908)
                        +.+++.                  ++++++++ |+.++.  ....++..+...++|++++....+. +++...+++++
T Consensus        61 --~~~l~~------------------~~~v~~vv~G~~~s~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~  120 (824)
T 4TLM_D           61 --ICDLMS------------------DKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIMADKEEASMFF  120 (824)
T ss_dssp             --HHHHHH------------------HHCCSEEEEEESCCCSHHHHHHHHHHHHHCCCEEECSHHHHSCCSCCCSSSCEE
T ss_pred             --HHHHhc------------------cCCCEEEEEcCCCChHHHHHHHHHHHHhhCCCEEEecCCCccccccccccceEE
Confidence              333332                  15789987 988776  4456677778899999986554432 22233578999


Q NP_000836.2     194 RVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREP-RPGEFEKIIKRLLET  272 (908)
Q Consensus       194 ~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~  272 (908)
                      ++.+++..+++++++++++++|+++++++.+++++....+.+++.+++. ++++.......... ...+....++++++ 
T Consensus       121 ~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~~~-  198 (824)
T 4TLM_D          121 QFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENKVRSTIENS-FVGWELEEVIHLDMSLDDIDSKIQNQLCK-  198 (824)
T ss_dssp             ESSCCHHHHHHHHHHHHHHTTCCEEEEEEESSTTTTHHHHHHHHHHHHS-SSCCEEEEEEEECSSSCCSSCHHHHHHTT-
T ss_pred             ecCCCHHHHHHHHHHHHHHcCCeEEEEEEEcCCChHHHHHHHHHHHHhc-cCCcEEEEEEEecCChhhhhHHHHHHHHh-
Confidence            9999999999999999988899999999988888888888888877764 34433221111101 11223444555653 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLA  351 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~  351 (908)
                      .++|+|++......+..+++++++.|+.+ .+.|+..+.|......  .......+.+                      
T Consensus       199 ~~~~~iv~~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~----------------------  254 (824)
T 4TLM_D          199 LQSPVILLYCTKEEATYIFEVAHSVGLTGYGFTWIVPSLVAGDTDT--VPDEFPTGLI----------------------  254 (824)
T ss_dssp             CCCSEEEEESCHHHHHHHHHHHHHHTTTSTTCEEEECHHHHTTSSC--CCTTSCTTCE----------------------
T ss_pred             cCCCEEEEECCHHHHHHHHHHHHHcCCCCCCeEEEeeccCCCCCCC--CCCcCCCCee----------------------
Confidence            57899888877777888999999888754 4567765533221100  0000000000                      


Q NP_000836.2     352 NNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG--YIG  429 (908)
Q Consensus       352 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~--~~~  429 (908)
                                  ...+.                           ..+..+++.+|||++++++|+++.....+..  ...
T Consensus       255 ------------~~~~~---------------------------~~~~~~~~~~Ydav~ll~~a~~~~~~~~~~~~~~~~  295 (824)
T 4TLM_D          255 ------------SVSYD---------------------------EWDYDLPARVRDGIAIITTAASTMLSEHNSIPQSKS  295 (824)
T ss_dssp             ------------EEECC---------------------------TTTCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
T ss_pred             ------------EEEee---------------------------cCCCCcchhHHHHHHHHHHHHHHHHHhcCCCCCCcc
Confidence                        00000                           0112356789999999999999886542210  011


Q NP_000836.2     430 LCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDA-PGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       430 ~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~-~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .|...   ...++..+.+++++.+|.|  | ++.||++|++ ...+.+++++.   ++.++.+|.|+..
T Consensus       296 ~~~~~~~~~~~~~~~l~~~l~~~~f~g--G-~~~f~~~g~~~~~~~~i~~~~~---~g~~~~v~~~~~~  358 (824)
T 4TLM_D          296 SCNNIQESRVYEAHMLKRYLINVTFEG--R-DLSFSEDGYQMHPKLVIILLNQ---ERKWERVGKYKDR  358 (824)
T ss_dssp             CSSSCCCTTCTTHHHHHHHHTSCEETT--E-ECCBCTTSBBSCCCEEEEEECS---TTCEEEEEEEETT
T ss_pred             cccccccccceeHHHHHHHHhcCccCC--c-eeeeCCCCccceeeEEEEEecC---CcceEEEEEEECc
Confidence            22211   1124567888888889988  7 8999999987 46788888873   3578899998764


No 110
>4EYQ_A Extracellular ligand-binding receptor; PSI-BIOLOGY, MCSG, MIDWEST CENTER FOR; HET: DHC, MSE, ENO; 1.96A {Rhodopseudomonas palustris}
Probab=99.41  E-value=1.8e-17  Score=176.21  Aligned_cols=348  Identities=13%  Similarity=0.160  Sum_probs=206.9  Template_Neff=12.200

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||+++|..+...          ..+.....+++.|++++|       |+++++.+.|+.+++..    ..+.+
T Consensus         3 ~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~~~~~a~~~~~-------g~~i~~~~~d~~~~~~~----~~~~~   61 (362)
T 4EYQ_A            3 AETNEITVGITVTTTGPAA----------ALGIPERNALEFVAKEIG-------GHPIKMIVLDDGGDPTA----ATTNA   61 (362)
T ss_dssp             CCCSSEEEEEEECCSSTTH----------HHHHHHHHHGGGSCSEET-------TEEEEEEEEECTTCHHH----HHHHH
T ss_pred             ccCCcEEEEEEEeCCCccH----------HhCccHHHHHHHHHHHhC-------CEEEEEEEEeCCCCHHH----HHHHH
Confidence            3456899999999875321          245677888999998875       35567777776655332    22333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                  .+++++||++.++.....+...+...++|+|.+......   ....++++++.+++.
T Consensus        62 ~~l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~---~~~~~~~~~~~~~~~  120 (362)
T 4EYQ_A           62 RRFVT------------------ESKADVIMGSSVTPPTVAVSNVANEAQVPHIALAPLPVT---PERAKWSVVMPQPIP  120 (362)
T ss_dssp             HHHHH------------------TSCCSEEEECSSHHHHHHHHHHHHHHTCCEEESSCCCCC---HHHHTTEEECSCCHH
T ss_pred             HHHHH------------------hCCCCEEEecCCChhHHHHHHHHHHhCCCEEEecCCCCC---CcccceeEEcCCCHH
Confidence            43332                  157889998876665556667788899999987654321   112466778888888


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ..++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  .+..+....+++++. .++|++++
T Consensus       121 ~~~~~~~~~l~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i~~  196 (362)
T 4EYQ_A          121 IMGKVLYEHMKKNNIKTVGYIGYSDSYGDLWFNDLKKQGEAM-GLKIVAEERFA--RPDTSVAGQVLKLVA-ANPDAILV  196 (362)
T ss_dssp             HHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHCCCCCHHT-TCEEEEEEEEC--TTCSCCHHHHHHHHH-HCCSEEEE
T ss_pred             HHHHHHHHHHHhCCCcEEEEEeecChhHHHHHHHHHHHHHHc-CCeEeeeeeeC--CCCCCHHHHHHHHHH-cCCCEEEE
Confidence            888899999888899999999866667777888888888765 35544322222  122345566666663 57898877


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      +..+..+..+++++++.|+.  ..|++.+.+...... ........+.+...........     .............|.
T Consensus       197 ~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~-----~~~~~~~~~~~~~f~  268 (362)
T 4EYQ_A          197 GASGTAAALPQTALRERGYN--GLIYQTHGAASMDFI-RIAGKSAEGVLMASGPVMDPEG-----QNDSALTKKPGLELN  268 (362)
T ss_dssp             ECCGGGGHHHHHHHHHTTCC--SEEEECGGGCSHHHH-HHHGGGGTTCEEEECGGGCTTT-----SCTTCTTHHHHHHHH
T ss_pred             eCChhHhHHHHHHHHHCCCC--ceEEeccccCcHHHH-HHhhhhhcCeEEeecccCCccc-----CCChhhcCCCChHHH
Confidence            66666677888888888874  356655433221110 0011122232221110000000     000000000111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+.+.++.                          ..+..++..+||++++++++++++.......        ...+++
T Consensus       269 ~~~~~~~~~--------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~~~~~--------~~~~~~  314 (362)
T 4EYQ_A          269 TAYETKYGP--------------------------NSRSQFAGHSFDAFKVLERVIPVALKTAKPG--------TQEFRE  314 (362)
T ss_dssp             HHHHHHHCT--------------------------TCCCHHHHHHHHHHHHHHHHHHHHTTTCCTT--------SHHHHH
T ss_pred             HHHHHHHCC--------------------------CCCCccccchhHHHHHHHHHHHHHHHhCCCC--------ChHHHH
Confidence            222221110                          0123567789999999999998875432100        012456


Q NP_000836.2     441 ELLGYIRA-VNFNGSAGTPVTFNENGD---APGRYDIFQYQ  477 (908)
Q Consensus       441 ~l~~~l~~-~~f~G~~G~~v~Fd~~G~---~~~~~~i~~~~  477 (908)
                      .+.++|++ ..|.|.+| ++.|+++++   +...+.+++++
T Consensus       315 ~l~~~l~~~~~~~g~~g-~~~f~~~~~~~~~~~~~~i~~~~  354 (362)
T 4EYQ_A          315 AIRKALLTEKDIAASQG-VYSFTETDRYGLDDRSRILLTVK  354 (362)
T ss_dssp             HHHHHHHHCCCEEETTE-EECCCSSCSSCCCGGGCEEEEEE
T ss_pred             HHHHHHHhcCCccccce-EEEecCCCCCCCCCCCcEEEEEE
Confidence            77888877 68999988 899987654   22355666665


No 111
>3LKB_B Probable branched-chain amino acid ABC; branched amino acid, ABC transporter; HET: VAL; 2.4A {Thermus thermophilus}
Probab=99.41  E-value=1.9e-17  Score=178.40  Aligned_cols=360  Identities=13%  Similarity=0.146  Sum_probs=216.8  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .+.+++||+++|.++..          ...+.....+++.|++++|+.+++ +|+++++.+.|+.+++..    ..+.++
T Consensus         4 ~~~~~~Ig~~~~~~~~~----------~~~~~~~~~g~~~a~~~~n~~g~~-~g~~~~~~~~d~~~~~~~----~~~~~~   68 (392)
T 3LKB_B            4 GQQQVTLFWSGAITGPT----------SDAGAPYGAAVEDYCKWANERKLV-PGVVFNCVVRDDQYNNAN----TQRFFE   68 (392)
T ss_dssp             CCEEEEEEEEECSSSTT----------HHHHHHHHHHHHHHHHHHHHHTSS-TTEEEEEEEEECTTCHHH----HHHHHH
T ss_pred             ccCcEEEEEEecCCCCc----------cccchhhHHHHHHHHHHHHHCCCC-CCEEEEEEEEeCCCChHH----HHHHHH
Confidence            45689999999986532          125567889999999999987654 477888888887665432    233333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.+                  +++++++++ ++.....+...+...++|+|......+. .....+++++++.+++..
T Consensus        69 ~l~~~------------------~~~~~ii~~-~~~~~~~~~~~~~~~~ip~i~~~~~~~~-~~~~~~~~~~~~~~~~~~  128 (392)
T 3LKB_B           69 EAVDR------------------FKIPVFLSY-ATGANLQLKPLIQELRIPTIPASMHIEL-IDPPNNDYIFLPTTSYSE  128 (392)
T ss_dssp             HHHHH------------------HCCSCEEEC-CHHHHHHHHHHHHHHTCCEEESCCCGGG-TSSSSCTTBCEEECCHHH
T ss_pred             HHHHc------------------cCCCEEEec-ccHHHHhHHHHHHHhCCCeeccccChHH-cCCCCCCceeecCCCHHH
Confidence            33321                  467888854 4544556667778889999987654322 111235678888999888


Q NP_000836.2     202 QAQAMVDIVT-ALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       202 ~~~~~~~~l~-~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      .++.+++++. +++|+++++++.++.++..+.+.+.+.+++. ++++.....+.  ....+....+++++. .+++++++
T Consensus       129 ~~~~~~~~l~~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~  204 (392)
T 3LKB_B          129 QVVALLEYIAREKKGAKVALVVHPSPFGRAPVEDARKAAREL-GLQIVDVQEVG--SGNLDNTALLKRFEQ-AGVEYVVH  204 (392)
T ss_dssp             HHHHHHHHHHHHSTTCEEEEEECSSHHHHTTHHHHHHHHHHH-TCEEEEEEECC--TTCCCCHHHHHHHHH-TTCCEEEE
T ss_pred             HHHHHHHHHHHhcCCCeEEEEECCCHhhcccHHHHHHHHHHc-CCeEEEEEecC--CCCCCHHHHHHHHHH-cCCCEEEE
Confidence            8999999984 6799999999976667777888888888775 35554322222  122345556666663 57888877


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      ...+..+..+++++++.|+.  ..+++.+.+...... ........+.+......          ..   ........+.
T Consensus       205 ~~~~~~~~~~~~~~~~~g~~--~~i~~~~~~~~~~~~-~~~~~~~~g~~~~~~~~----------~~---~~~~~~~~~~  268 (392)
T 3LKB_B          205 QNVAGPVANILKDAKRLGLK--MRHLGAHYTGGPDLI-ALAGDAAEGFLWATSFY----------MA---HEDTPGIRLQ  268 (392)
T ss_dssp             ESCHHHHHHHHHHHHHTTCC--CEEEECGGGCSHHHH-HHHGGGGTTCEEEESBC----------CT---TSCCHHHHHH
T ss_pred             eCCChhHHHHHHHHHHcCCC--CcEEEccccCCHHHH-HHHHHHhCCEEEEeccC----------CC---CCCCHHHHHH
Confidence            76566677889999888874  345554432221110 00111122222111100          00   0000111122


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+.+.++...                       ..........+||++++++.|++++....           ...+++
T Consensus       269 ~~~~~~~~~~~-----------------------~~~~~~~~~~~yda~~~l~~al~~~~~~~-----------~~~~~~  314 (392)
T 3LKB_B          269 KEIGRKYGRPE-----------------------NFIESVNYTNGMLAAAIAVEAIRRAQERF-----------KRITNE  314 (392)
T ss_dssp             HHHHHHTTCCH-----------------------HHHTCHHHHHHHHHHHHHHHHHHHHHHHH-----------SCCSHH
T ss_pred             HHHHHHHCCCc-----------------------hhhcchHHHHHHHHHHHHHHHHHHHHHHh-----------CCCCHH
Confidence            22222221100                       00000112268999999999998875421           012455


Q NP_000836.2     441 ELLGYIRAVN----------FNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       441 ~l~~~l~~~~----------f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .+.+.|++..          |.|.+|.++.|+++|++. ..+.+++++    ++.++.|+.|...
T Consensus       315 ~l~~~l~~~~~~~~~~~~~~~~g~~G~~i~f~~~~~~~~~~~~i~~~~----~g~~~~v~~~~~~  375 (392)
T 3LKB_B          315 TVYQAIVGMNGPNAFKPGFAVSTKQGVEIDFTKSEHTGAEGLRILEAK----GGRFVPVTEPFTS  375 (392)
T ss_dssp             HHHHHHHTCSGGGCBCCSSBCCCSSSCSBCCCSSCCEEECCBEEEEEE----TTEEEECSCCBCC
T ss_pred             HHHHHHHhccCCCCCCCccccccCCcceeeeccCCCCCCccEEEEEEc----CCEEEECCCCcCH
Confidence            6667776553          556665369999887765 567787776    3578999999865


No 112
>4F8J_A Putative branched-chain amino acid transport; lignin degratation, Structural Genomics, PSI-Biology; HET: GOL, EPE, SO4, HC4; 1.6A {Rhodopseudomonas palustris}
Probab=99.39  E-value=2.8e-17  Score=174.67  Aligned_cols=348  Identities=14%  Similarity=0.158  Sum_probs=206.1  Template_Neff=12.300

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||+++|..+...          ..+.....+++.+++++|       |+++++.+.|+.+++.    ...+.+
T Consensus         3 ~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~-------g~~~~~~~~d~~~~~~----~~~~~~   61 (362)
T 4F8J_A            3 AETNEITIGITVTTTGPAA----------ALGIPERNALEFVAKEIG-------GHPLKVIVLDDGGDPT----AATTNA   61 (362)
T ss_dssp             -CCSSEEEEEEECCSSTTH----------HHHHHHHHGGGGSCSEET-------TEEEEEEEEECTTCHH----HHHHHH
T ss_pred             ccCCceEEEEEEcCCCchH----------HhCchHHHHHHHHHHHhC-------CEEEEEEEEeCCCCHH----HHHHHH
Confidence            3456899999999875321          245677888888888875       4567777777655532    222333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                  .++++++|++.++.....+...+...++|+|..+.....   ....++++++.+++.
T Consensus        62 ~~~~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~---~~~~~~~~~~~~~~~  120 (362)
T 4F8J_A           62 RRFVT------------------ESKADVIMGSSVTPPTVAVSNVANEAQVPHIALAPLPIT---PERAKWSVAMPQPIP  120 (362)
T ss_dssp             HCCCC------------------CSCCSEEEECSSHHHHHHHHHHHHHHTCCEEESSCCCCC---TTTTTTEEECSCCHH
T ss_pred             HHHHh------------------hcCCCEEEecCCChHHHHHHHHHHHhCCCEEEcCCCCCC---ccccceeeecCCChH
Confidence            33332                  157899998876665556677788899999987653221   113467788888888


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ..++.+++++.+.+|++|++++.++.++..+.+.+++.+++. ++++.....+.  ....+....+++++. .+++++++
T Consensus       121 ~~~~~~~~~l~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~  196 (362)
T 4F8J_A          121 IMGKVLYEHMKKNNIKTVGYIGYSDSYGDLWFNDLKKQGEAM-GLKIVAEERFA--RPDTSVAGQVLKLVA-ANPDAILV  196 (362)
T ss_dssp             HHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHCCCCCHHT-TCEEEEEEEEC--TTCSCCHHHHHHHHH-HCCSEEEE
T ss_pred             HHHHHHHHHHHhCCCeEEEEEEecCcchHHHHHHHHHHHHHc-CCEEEeeeeeC--CCCCChHHHHHHHHH-cCCCEEEE
Confidence            888899999888899999999966667777788888887765 35554322222  122345556666653 57888877


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      +.++..+..+++++++.|+.  ..|++.+.+...... ........+.+...........   . ... .........|.
T Consensus       197 ~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~---~-~~~-~~~~~~~~~f~  268 (362)
T 4F8J_A          197 GASGTAAALPQTSLRERGYK--GLIYQTHGAASMDFI-RIAGKSAEGVLMASGPVMDPEG---Q-DDS-ALTKKPGLELN  268 (362)
T ss_dssp             ECCHHHHHHHHHHHHHTTCC--SEEEECGGGCBTHHH-HHHGGGGTTCEEEECGGGCGGG---S-CTT-CTTHHHHHHHH
T ss_pred             eCCHHHchHHHHHHHHCCCC--ceEEeecccCCHHHH-HHccccccCeEEecccccCcCC---C-Cch-hhcCCcchHHH
Confidence            76666677888998888874  355555433221110 0011122232221110000000   0 000 00000111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++.                          ..++.++..+||+++++++|++++.......        ...+++
T Consensus       269 ~~~~~~~~~--------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~~~~~--------~~~~~~  314 (362)
T 4F8J_A          269 TAYEAKYGP--------------------------NSRSQFAAHSFDAFKVLERVVPVALKTAKPG--------TQEFRE  314 (362)
T ss_dssp             HHHHHHHCT--------------------------TCCBHHHHHHHHHHHHHHHHHHHHHTTCCTT--------SHHHHH
T ss_pred             HHHHHHHCC--------------------------CCCCccccchhHHHHHHHHHHHHHHHhCCCC--------CHHHHH
Confidence            222221110                          0123567889999999999998665432100        013456


Q NP_000836.2     441 ELLGYIRA-VNFNGSAGTPVTFNENGDA---PGRYDIFQYQ  477 (908)
Q Consensus       441 ~l~~~l~~-~~f~G~~G~~v~Fd~~G~~---~~~~~i~~~~  477 (908)
                      .+.+.|++ ..|.|.+| ++.|+++++.   ...+.+++++
T Consensus       315 ~l~~~l~~~~~~~g~~g-~i~f~~~~~~~~~~~~~~i~~~~  354 (362)
T 4F8J_A          315 AIRKALVSEKDIAASQG-VYSFTETDRYGLDDRSRILLTVK  354 (362)
T ss_dssp             HHHHHHHHSCCEECSSC-EECCCSSCSSCCCGGGCEEEEEE
T ss_pred             HHHHHHHhccCccccce-eEEecCCCCCCcCcCCcEEEEEE
Confidence            78888887 58999988 8999986542   2356677765


No 113
>4U4G_D GluA2*; Ionotropic glutamate receptor, AMPA receptor; HET: NAG, ZK1, BMA; 4.49A {Rattus norvegicus}
Probab=99.39  E-value=2.9e-17  Score=195.81  Aligned_cols=356  Identities=15%  Similarity=0.188  Sum_probs=224.1  Template_Neff=11.500

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~~~~  122 (908)
                      ++++||++.|.++.                ....|++.|++++|++     |+++++.+.|+. +++.    .+.+.+++
T Consensus         1 ~~i~Ig~~~~~~g~----------------~~~~g~~~a~~~in~~-----g~~l~~~~~d~~~~~~~----~~~~~~~~   55 (822)
T 4U4G_D            1 NSIQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSF----AVTNAFCS   55 (822)
T ss_dssp             CEEEEEEEEETTCH----------------HHHHHHHHHHHHHCCS-----SCEEEEEEEEECTTCHH----HHHHHHHH
T ss_pred             CceeEEEecCCCCh----------------HHHHHHHHHHhhccCC-----CceeeeeEEecCCCCHH----HHHHHHHH
Confidence            36899999988742                4678999999999975     467888888865 3322    22233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      +..                   +++++++|+.++..+.++++.+...++|+++++.+++     ..+++++++.++   .
T Consensus        56 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~---~  108 (822)
T 4U4G_D           56 QFS-------------------RGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPD---L  108 (822)
T ss_dssp             HHH-------------------HCCSCEEECCCTTTHHHHHHHHHHHCCCEEESSCCCS-----SCCSSEEECSCC---C
T ss_pred             HHh-------------------hCeeEEEecCChhHHHHHHHHHhccCCeEEeCCCCCC-----CCCCeEEEecCC---H
Confidence            332                   5789999998887777888888899999998876543     246889999887   4


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPR--EPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ++.+++++++++|+++++++ +++++....+.+++.+++. ++++.....++.  +.+..++...++++++ .++|+|++
T Consensus       109 ~~~~~~~l~~~~~~~v~iv~-~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~i~~  185 (822)
T 4U4G_D          109 KGALLSLIEYYQWDKFAYLY-DSDRGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKERRVIL  185 (822)
T ss_dssp             HHHHHHHHHHTTCCEEEEEE-CGGGCTHHHHHHHHHHHHH-TCEEEEEECSSCCSSSCSTTTTTHHHHTTS-SCCCEEEE
T ss_pred             HHHHHHHHHHcCCCEEEEEE-cCcchHHHHHHHHHHHHhc-CCeEEEEEccCCCCCCCcchhHHHHHHHHh-cCCcEEEE
Confidence            67788888888999999999 5667777777787777764 455544332210  0122456667777763 57899988


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      .+....+..+++++++.|+.. .+.|++.+.+...... ........+.......               ....+....|
T Consensus       186 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~---------------~~~~~~~~~f  249 (822)
T 4U4G_D          186 DCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGAEVSGFQIV---------------DYDDSLVSKF  249 (822)
T ss_dssp             ESCHHHHHHHHHHHHHHTCSSTTCEEEECSSBTTTSCC-TTTTTSSCEEEEEESS---------------CTTSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHhCCCCCCeEEEEeeCCCCCCch-HhcccCCeeEEEEEEe---------------eCCchHHHHH
Confidence            877767788899998888753 3566665422211100 0000001111111000               0011122233


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~~~~-  434 (908)
                      .+.+++.++....           +  .      ....++.++..+|||++++++|++++......    .....|... 
T Consensus       250 ~~~~~~~~~~~~~-----------~--~------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~~~~~~  310 (822)
T 4U4G_D          250 IERWSTLEEKEYP-----------G--A------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANP  310 (822)
T ss_dssp             HHHHTTSCTTTST-----------T--C------CSSCCCHHHHHHHHHHHHHHHHHHHHHHTTCCCCCSSCCCCTTCSS
T ss_pred             HHHHHhcchhcCC-----------C--C------CCCCCchhHHHHHHHHHHHHHHHHHHHHhccccccCCCCCCCccCC
Confidence            3434333321000           0  0      00123456788999999999999998653210    001122211 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                        ...+++.+.++|++..|.|.+| ++.|+++|++.. .+.+++++    ++.++.+|.|...
T Consensus       311 ~~~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~v~~~~~~  368 (822)
T 4U4G_D          311 AVPWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEV  368 (822)
T ss_dssp             CCCCTTHHHHHHHHHHCCEEETTE-EECBCTTCCBCSCCEEEEEEE----TTEEEEEEEEETT
T ss_pred             CCCccchHHHHHHHHhccccCCCc-cEEECCCCcEEEeEEEEEEec----CCCceeeEEeeCC
Confidence              1124567888888889999988 899999888764 78888887    3568888888753


No 114
>6PEQ_D Glutamate receptor 2, Protein cornichon; ionotropic glutamate receptor, AMPA receptor; HET: CLR, OLC, PAM, ZK1; 2.97A {Rattus norvegicus}
Probab=99.39  E-value=3.4e-17  Score=196.89  Aligned_cols=360  Identities=15%  Similarity=0.192  Sum_probs=225.1  Template_Neff=11.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILD-TCSRDTYALEQSLT  118 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d-~~~~~~~a~~~~~~  118 (908)
                      ...+++++||++.|.++.                ....|++.|++++|++     |.++++.+.| +++++..    +.+
T Consensus        21 ~~~~~~i~Ig~~~~~~g~----------------~~~~g~~~a~~~in~~-----g~~l~~~~~d~~~~~~~~----~~~   75 (889)
T 6PEQ_D           21 GVSSNSIQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSFA----VTN   75 (889)
T ss_pred             hccCCeEEEeEeeCCCCh----------------HHHHHHHHHHHhcccc-----CceeccceeecCccCHHH----HHH
Confidence            456689999999998652                4678999999999975     4678888888 4444322    223


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      .+++++.                   +++++++|+.++..+.+++..+...++|++++...++     ..+++++++.++
T Consensus        76 ~~~~l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~  131 (889)
T 6PEQ_D           76 AFCSQFS-------------------RGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPD  131 (889)
T ss_pred             HHHHHHh-------------------cCeeEEEEcCChHHHHHHHHHHhccCCcEEEcCCCCC-----CCCCcEEEeecC
Confidence            3333332                   5789999998887777888888999999998876443     247889999887


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPR--EPRPGEFEKIIKRLLETPNAR  276 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~  276 (908)
                         .++++++++++++|+++++++ +++++....+.+++.+++. ++++......+.  ..+..++...++++++ .++|
T Consensus       132 ---~~~~~~~~~~~~~~~~v~ii~-~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~i~~-~~~~  205 (889)
T 6PEQ_D          132 ---LKGALLSLIEYYQWDKFAYLY-DSDRGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKER  205 (889)
T ss_pred             ---hHHHHHHHHHHhCCCEEEEEE-eCcchhHHHHHHHHHHHhh-CCeEEEEEccCCCCCCCchhhHHHHHHhcc-CCCe
Confidence               577888888888999999999 5567777777787777765 355543322210  0112355667777763 5789


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRR  355 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  355 (908)
                      +|++...+..+..+++++++.|+.. .+.|++.+.+...... ........+.......               ....+.
T Consensus       206 ~vi~~~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~---------------~~~~~~  269 (889)
T 6PEQ_D          206 RVILDCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGANVSGFQIV---------------DYDDSL  269 (889)
T ss_pred             EEEEECCHHHHHHHHHHHHHhCCCCCCeEEEEEeCCCCcccH-HHhccCCcceEEEEEe---------------eCCcHH
Confidence            9988877777888999998888753 4567765532221100 0000001111110000               000111


Q NP_000836.2     356 NVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLC  431 (908)
Q Consensus       356 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~  431 (908)
                      ...|.+.+.+.++..             +...      ....++.++..+|||+++++.|++++......    .....|
T Consensus       270 ~~~f~~~~~~~~~~~-------------~~~~------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~~  330 (889)
T 6PEQ_D          270 VSKFIERWSTLEEKE-------------YPGA------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDC  330 (889)
T ss_pred             HHHHHHHHHhccccc-------------CCCC------CCCCCChHHHHHHHHHHHHHHHHHHHHHhhhccccCCCCCCC
Confidence            222333333332210             0000      00123456788999999999999988643210    000122


Q NP_000836.2     432 PRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       432 ~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ...   ...++..+.+.|++..|.|.+| ++.||++|++.. .+.+.+++    ++.++.++.|...
T Consensus       331 ~~~~~~~~~~~~~i~~~l~~~~~~g~~G-~v~f~~~g~~~~~~~~i~~~~----~~~~~~~~~~~~~  392 (889)
T 6PEQ_D          331 LANPAVPWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEV  392 (889)
T ss_pred             CCCCCCCccchHHHHHHHHhcCccCCCc-cEEECCCCcEeeeEEEEEEec----cCCceEEEEEeCC
Confidence            110   1124566778888889999988 899999888754 78888887    2457777878754


No 115
>3UK0_A Extracellular ligand-binding receptor; STRUCTURAL GENOMICS, PSI-BIOLOGY, MIDWEST CENTER; HET: ENO, MSE, SO4; 1.49A {Rhodopseudomonas palustris}
Probab=99.38  E-value=3.5e-17  Score=173.93  Aligned_cols=348  Identities=14%  Similarity=0.163  Sum_probs=203.7  Template_Neff=12.200

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||+++|.++...          ..+.....+++.+++++|       |.++++.+.|+.+++..    ..+.+
T Consensus         3 ~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~~~~~a~~~~~-------g~~~~~~~~~~~~~~~~----~~~~~   61 (362)
T 3UK0_A            3 AETNEITVGISVTTTGPAA----------ALGIPERNALEFVVKEIS-------GHPIKIIVLDDGGDPTA----ATTNA   61 (362)
T ss_dssp             -CCCCEEEEEEECCSSTTH----------HHHHHHHHGGGGSCSEET-------TEEEEEEEEECTTCHHH----HHHHH
T ss_pred             ccCCcEEEEEEEecCCCcH----------HhCCCHHHHHHHHHHHhc-------CeEEEEEEEeCCCCHHH----HHHHH
Confidence            3456899999999865321          245677889999999987       34566667776555332    22333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                  .+++++||++.++.....+...+...++|+|........   ....++++++.+++.
T Consensus        62 ~~l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~---~~~~~~~~~~~~~~~  120 (362)
T 3UK0_A           62 RRFVT------------------ESKADVIMGSSVTPPSVAISNVANEAQIPHIALAPLPIT---PERAKWSVVMPQPIP  120 (362)
T ss_dssp             HHHHH------------------TSCCSEEEECSSHHHHHHHHHHHHHHTCCEEESSCCCCC---TTTTTTEEECSCCHH
T ss_pred             HHHHH------------------hcCCCEEEecCCChHHHHHHHHHHHcCCCEEEccCCCCC---CcccCceeecCCCHH
Confidence            33332                  157889998776655556667778889999987654221   112466788888888


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ..++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  ....+....+++++. .+++++++
T Consensus       121 ~~~~~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~  196 (362)
T 3UK0_A          121 IMGKVLYEHMKKNNVKTVGYIGYSDSYGDLWFNDLKKQGEAM-GLKIVGEERFA--RPDTSVAGQALKLVA-ANPDAILV  196 (362)
T ss_dssp             HHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHCCCCCHHT-TCEEEEEEEEC--TTCSCCHHHHHHHHH-HCCSEEEE
T ss_pred             HHHHHHHHHHHHCCCCEEEEEEecCcchHHHHHHHHHHHHHc-CCEEeeEEEeC--CCCCChHHHHHHHHH-cCCCEEEE
Confidence            888889998887899999999966667777888888888765 35544322222  112334455666653 47888867


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA  360 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  360 (908)
                      +..+..+..+++++++.|+.  ..+++.+.+...... ........+.+...........     .............|.
T Consensus       197 ~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~g~~~~~~~~~~~~~-----~~~~~~~~~~~~~f~  268 (362)
T 3UK0_A          197 GASGTAAALPQTTLRERGYN--GLIYQTHGAASMDFI-RIAGKSAEGVLMASGPVMDPEG-----QDDTALTKKPGMALV  268 (362)
T ss_dssp             ECCHHHHHHHHHHHHHTTCC--SEEEECGGGCSHHHH-HHHGGGGTTCEEEECGGGCSTT-----SCTTCTTHHHHHHHH
T ss_pred             eCCHHHchhHHHHHHHcCCc--ceEEEcCcccCHHHH-HHhhhhhcCcEEeecCCCCCCC-----CCchhccCcchHHHH
Confidence            66666677888998888874  355555433221110 0011122333221110000000     000000000111222


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.|++.++.                          ..++.++..+||+++++++++++++......        ....++
T Consensus       269 ~~~~~~~~~--------------------------~~~~~~~~~~yda~~~~~~a~~~a~~~~~~~--------~~~~~~  314 (362)
T 3UK0_A          269 KVYEEKYGP--------------------------SSRSQFAGHSYDAFKVLERVVPVALKKAKPG--------TQEFRE  314 (362)
T ss_dssp             HHHHHHHCT--------------------------TCCCHHHHHHHHHHHHHHHHHHHHHTTCCTT--------SHHHHH
T ss_pred             HHHHHHHCC--------------------------CCCCcccccchhHHHHHHHHHHHHHHhcCCC--------CHHHHH
Confidence            222221110                          0123567789999999999877665432100        112455


Q NP_000836.2     441 ELLGYIRA-VNFNGSAGTPVTFNENGD---APGRYDIFQYQ  477 (908)
Q Consensus       441 ~l~~~l~~-~~f~G~~G~~v~Fd~~G~---~~~~~~i~~~~  477 (908)
                      .+.++|++ ..|+|.+| ++.|+++++   +...+.+++++
T Consensus       315 ~l~~~l~~~~~~~g~~g-~i~f~~~~~~~~~~~~~~i~~~~  354 (362)
T 3UK0_A          315 ALREAFLTEKDIAASQG-VYNFTETDRYGLDDRSRILLTVK  354 (362)
T ss_dssp             HHHHHHHHCCCEECSSC-EECCCSSCSSCCCGGGCEEEEEE
T ss_pred             HHHHHHHcCCccccccc-eEEeCCCCccccCccceEEEEEE
Confidence            67777775 57899888 899987643   22355666665


No 116
>4TLL_C GluN1/GluN2B; Neurotransmitter receptor, NMDA receptor, GluN1/GluN2B; HET: JEG, QEM, NAG; 3.59A {Xenopus laevis}
Probab=99.38  E-value=3.6e-17  Score=194.78  Aligned_cols=349  Identities=18%  Similarity=0.271  Sum_probs=228.5  Template_Neff=11.000

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.++                  ...|++.|++++|+.+   .|.++++...|+.+++.. .+...+.+++
T Consensus         3 ~~~i~IG~i~~~~~------------------~~~~~~~a~~~~n~~g---~g~~i~l~~~d~~~~~~~-~~~~~~~~~~   60 (823)
T 4TLL_C            3 PKIVNIGAVLSTKK------------------HEQIFREAVNQANFFH---FTRKIQLNATSVTHRPNA-IQMALSVCED   60 (823)
T ss_dssp             CEEEEEEEEESSHH------------------HHHHHHHHHHHHHHSS---CTTTEEEEECCEECCSSH-HHHHHHCCCC
T ss_pred             CceeeeeEEecCch------------------HHHHHHHHHHHHhhcc---CCCceeccccccCCCCCH-HHHHHHHHHH
Confidence            47899999998752                  4578999999999865   267788888887655332 0113333333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-----IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-----~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +..                   +++++++|+.++..+     ..++..+...++|+|++.+..+.+.++..+++++++.+
T Consensus        61 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~  121 (823)
T 4TLL_C           61 LIS-------------------SQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP  121 (823)
T ss_dssp             CGG-------------------GCCSCEEECCCSSCCTTCTTHHHHHHHHHTTCCEEESSCCCGGGSCTTTCSSEEESSC
T ss_pred             HHh-------------------cCceEEEEcCCCCCCCcCCchHHHHhhccccCCEEEeecCCcccCCCCcccceeecCC
Confidence            332                   478999998887776     55666888899999998876665554335788999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ++..+++++++++++++|+++++++.+++++....+.+++.+++. ++++.....+.  .+..+....++++++ .++|+
T Consensus       122 ~~~~~~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~~~~-~~~~~  197 (823)
T 4TLL_C          122 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEK-ESKADKVLQFE--PGTKNLTALLLEAKE-LEARV  197 (823)
T ss_dssp             CSGGGHHHHHHHHHHHTCCCCEEEEESSHHHHHHHHHHHHHHTSS-TTCCCEEEEEC--TTCSCCHHHHHHHHH-SSCCE
T ss_pred             CHHHHHHHHHHHHHHcCCCEEEEEEecCcchHHHHHHHHHHHHhc-cccccEEeccC--CCCccHHHHHHHHHh-CCceE
Confidence            999999999999988899999999987788888888888888775 45554333232  122345666777763 57899


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      |++.+.+..+..+++++++.|+.. .+.|++.+.+....    .......+.+.                          
T Consensus       198 vv~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~----~~~~~~~~~~~--------------------------  247 (823)
T 4TLL_C          198 IILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGS----ALRYAPDGIIG--------------------------  247 (823)
T ss_dssp             EEEECCHHHHHHHHHHHHHTTTTSTTCEEEECTTTSSTH----HHHSCCTTCEE--------------------------
T ss_pred             EEEECCHHHHHHHHHHHHhcCccCCCeEEEEecCCCCch----hhhcCCCceEE--------------------------
Confidence            888877777888999998888753 34455543221110    00000000000                          


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGY-IGLCPRM-  434 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~-~~~~~~~-  434 (908)
                         ...                                 ..+..++..+|||++.++.|+++......... ...|... 
T Consensus       248 ---~~~---------------------------------~~~~~~~~~~ydav~~~~~a~~~~~~~~~~~~~~~~~~~~~  291 (823)
T 4TLL_C          248 ---LQL---------------------------------INGKNESAHISDAVAVVAQAIHELFEMEQITDPPRGCVGNT  291 (823)
T ss_dssp             ---EEE---------------------------------TTSSCSHHHHHHHHHHHHHHHHHHTTSSSCCCCCSCSTTCC
T ss_pred             ---EEE---------------------------------cCCCCccchHHHHHHHHHHHHHHHHhcCCCCCCCCCcCCCC
Confidence               000                                 00122456789999999999988764321110 0111110 


Q NP_000836.2     435 -STIDGKELLGYIRAV-NFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLH-LKVEDMQWAHR  507 (908)
Q Consensus       435 -~~~~~~~l~~~l~~~-~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~-~~~~~i~w~~~  507 (908)
                       ...+++.+.+.|++. .|.|.+| .+.||++|++. ..+.+.+++    ++.++.++.|+.... .....+.|+.+
T Consensus       292 ~~~~~~~~l~~~l~~~~~~~G~~G-~i~fd~~g~~~~~~~~i~~~~----~~~~~~~~~~~~~~~~~~~~~~~~~~~  363 (823)
T 4TLL_C          292 NIWKTGPLFKRVLMSSKYPDGVTG-RIEFNEDGDRKFAQYSIMNLQ----NRKLVQVGIFDGSYIIQNDRKIIWPGG  363 (823)
T ss_dssp             SCCTTHHHHHHHHHTCCCTTCTTS-CCEECTTSCEESCCEEEEEEC----SSSEEEEEEECSSSCEECSSCCCCTTS
T ss_pred             CccccHHHHHHHHHcCCCCCCccc-cEEECCCCCEEeeEEEEEEcc----CCceEEEEEeeCCceeecCCceeCCCC
Confidence             012345677777754 6889888 89999988874 677788876    357899999986532 12224667653


No 117
>4TLM_C GluN1/GluN2B; neurotransmitter receptor, NMDA receptor, GluN1/GluN2B; HET: NAG, QEM, JEG; 3.77A {Xenopus laevis}
Probab=99.38  E-value=3.6e-17  Score=194.78  Aligned_cols=349  Identities=18%  Similarity=0.271  Sum_probs=228.5  Template_Neff=11.000

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.++                  ...|++.|++++|+.+   .|.++++...|+.+++.. .+...+.+++
T Consensus         3 ~~~i~IG~i~~~~~------------------~~~~~~~a~~~~n~~g---~g~~i~l~~~d~~~~~~~-~~~~~~~~~~   60 (823)
T 4TLM_C            3 PKIVNIGAVLSTKK------------------HEQIFREAVNQANFFH---FTRKIQLNATSVTHRPNA-IQMALSVCED   60 (823)
T ss_dssp             CCEEEEEEEESCHH------------------HHHHHHHHHHHHHHTS---CTTTCEEEEEEEECCSSH-HHHHHHCCCC
T ss_pred             CceeeeeEEecCch------------------HHHHHHHHHHHHhhcc---CCCceeccccccCCCCCH-HHHHHHHHHH
Confidence            47899999998752                  4578999999999865   267788888887655332 0113333333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-----IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-----~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +..                   +++++++|+.++..+     ..++..+...++|+|++.+..+.+.++..+++++++.+
T Consensus        61 l~~-------------------~~v~~vig~~~s~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~  121 (823)
T 4TLM_C           61 LIS-------------------SQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP  121 (823)
T ss_dssp             CGG-------------------GTCSCEEECCCSSCCSSCTTSHHHHHHHHHTCCEEESSCCCGGGSCTTTCSSEEESSC
T ss_pred             HHh-------------------cCceEEEEcCCCCCCCcCCchHHHHhhccccCCEEEeecCCcccCCCCcccceeecCC
Confidence            332                   478999998887776     55666888899999998876665554335788999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ++..+++++++++++++|+++++++.+++++....+.+++.+++. ++++.....+.  .+..+....++++++ .++|+
T Consensus       122 ~~~~~~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~~~~-~~~~~  197 (823)
T 4TLM_C          122 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEK-ESKADKVLQFE--PGTKNLTALLLEAKE-LEARV  197 (823)
T ss_dssp             CTTTHHHHHHHHHHHHTCCCCEEEEESSHHHHHHHHHHHHHHHHS-SCCCSCEEEEC--TTCSCCHHHHHHHHH-SSCCE
T ss_pred             CHHHHHHHHHHHHHHcCCCEEEEEEecCcchHHHHHHHHHHHHhc-cccccEEeccC--CCCccHHHHHHHHHh-CCceE
Confidence            999999999999988899999999987788888888888888775 45554333232  122345666777763 57899


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      |++.+.+..+..+++++++.|+.. .+.|++.+.+....    .......+.+.                          
T Consensus       198 vv~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~----~~~~~~~~~~~--------------------------  247 (823)
T 4TLM_C          198 IILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGS----ALRYAPDGIIG--------------------------  247 (823)
T ss_dssp             EEEECCHHHHHHHHHHHHHTTTTSTTCEEEECHHHHSTH----HHHHCCTTCEE--------------------------
T ss_pred             EEEECCHHHHHHHHHHHHhcCccCCCeEEEEecCCCCch----hhhcCCCceEE--------------------------
Confidence            888877777888999998888753 34455543221110    00000000000                          


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGY-IGLCPRM-  434 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~-~~~~~~~-  434 (908)
                         ...                                 ..+..++..+|||++.++.|+++......... ...|... 
T Consensus       248 ---~~~---------------------------------~~~~~~~~~~ydav~~~~~a~~~~~~~~~~~~~~~~~~~~~  291 (823)
T 4TLM_C          248 ---LQL---------------------------------INGKNESAHISDAVAVVAQAIHELFEMEQITDPPRGCVGNT  291 (823)
T ss_dssp             ---EEE---------------------------------TTSSCHHHHHHHHHHHHHHHHHHHTTSSCCCCCCSSSTTCC
T ss_pred             ---EEE---------------------------------cCCCCccchHHHHHHHHHHHHHHHHhcCCCCCCCCCcCCCC
Confidence               000                                 00122456789999999999988764321110 0111110 


Q NP_000836.2     435 -STIDGKELLGYIRAV-NFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQLH-LKVEDMQWAHR  507 (908)
Q Consensus       435 -~~~~~~~l~~~l~~~-~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~~~-~~~~~i~w~~~  507 (908)
                       ...+++.+.+.|++. .|.|.+| .+.||++|++. ..+.+.+++    ++.++.++.|+.... .....+.|+.+
T Consensus       292 ~~~~~~~~l~~~l~~~~~~~G~~G-~i~fd~~g~~~~~~~~i~~~~----~~~~~~~~~~~~~~~~~~~~~~~~~~~  363 (823)
T 4TLM_C          292 NIWKTGPLFKRVLMSSKYPDGVTG-RIEFNEDGDRKFAQYSIMNLQ----NRKLVQVGIFDGSYIIQNDRKIIWPGG  363 (823)
T ss_dssp             SCCTHHHHHHHHHHTCCCCCCSSC-CCCBCTTSCBCSCCEEEEECG----GGSCEEEEEEETTEEEECSSCCCCSSS
T ss_pred             CccccHHHHHHHHHcCCCCCCccc-cEEECCCCCEEeeEEEEEEcc----CCceEEEEEeeCCceeecCCceeCCCC
Confidence             012345677777754 6889888 89999988874 677788876    357899999986532 12224667653


No 118
>4MPT_B Putative leu/ile/val-binding protein; Structural Genomics, PSI-Biology, Midwest Center; HET: ACY, MSE; 1.75A {Bordetella pertussis Tohama I}
Probab=99.38  E-value=3.6e-17  Score=175.27  Aligned_cols=354  Identities=16%  Similarity=0.200  Sum_probs=209.4  Template_Neff=11.900

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVR-ILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~-~~d~~~~~~~a~~~~~~~~  120 (908)
                      .+++++||+++|.++...          ..+.....|++.|++++|+.+++. |+++++. +.|+.+++..    ..+.+
T Consensus         3 ~~~~~~Ig~~~~~~~~~~----------~~~~~~~~~~~~a~~~~n~~~g~~-g~~v~l~~~~d~~~~~~~----~~~~~   67 (380)
T 4MPT_B            3 AADTIKIGMTSALTGPYN----------EFGEGNRRAVELAVEQWNAKGGIN-GKKIEIAMLLDDQLNPDR----AVQNI   67 (380)
T ss_dssp             --CEEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHHTTTSBT-TBEEEEEEEEECTTCHHH----HHHHH
T ss_pred             cCCceEEEEEecCCCCch----------HHhHHHHHHHHHHHHHHHHCCCCC-CeEEEEEEEEcCCCCHHH----HHHHH
Confidence            457899999999875421          245678899999999999876543 6778877 6776655432    33344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSD------NTRYDFFSR  194 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~------~~~~~~~~~  194 (908)
                      ++++.+                  ++++++||+.++.....+...+...++|+|......+.+..      ...++++++
T Consensus        68 ~~l~~~------------------~~~~~vig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~  129 (380)
T 4MPT_B           68 RAILDN------------------KDIVGIIGPAGSGPMLAVIDMVQADGRPYMNPIAQTPVVTYPGEKTGEKPRPNVFS  129 (380)
T ss_dssp             HHHHTC------------------TTCCCEECCSSHHHHHHHHHHHHHHCSCEEECSCCCGGGTCTTSSTTSSCCTTEEE
T ss_pred             HHHHhc------------------CCEEEEECCCCCHHHHHHHHHHHHhCCcEEcccCCCCcccCCCCcCCCCCCCceEE
Confidence            444321                  47889999887766667778888899999988766554321      113577899


Q NP_000836.2     195 VVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       195 ~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      +.+++...+..+++++.+ +|++|++++.++.++..+.+.+++.+++..++++.....+.  .+..++...+++++. .+
T Consensus       130 ~~~~~~~~~~~~~~~l~~-~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~~~v~~~~~~~--~~~~~~~~~~~~~~~-~~  205 (380)
T 4MPT_B          130 FALQNDIEAVAMGEYLAK-KFKRVGIIHESTAYGVTGVDYLAASIAKNGGAKPVATDSYN--QGAQDMTAQVARMKR-AN  205 (380)
T ss_dssp             CSCCHHHHHHHHHHHHHH-HCSSEEEEEESSHHHHHHHHHHHHHHHHTTCCCCSEEEEEC--TTCSCCHHHHHHHHT-TT
T ss_pred             EecCchHHHHHHHHHHHh-hCCeEEEEecCChhhhhHHHHHHHHHHHcCCCeeeEEEeec--CCCCchHHHHHHHHH-CC
Confidence            999988888888888876 89999999966667777888888777653224443322222  122345566666663 57


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNR  354 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~  354 (908)
                      ++++++...+..+..+++++++.|+.  ..+++.+.+...... ........+.+......         +..   ...+
T Consensus       206 ~~~i~~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~---------~~~---~~~~  270 (380)
T 4MPT_B          206 VDAIAAIGLGKDLAVLRRTMARLNVN--VPLAASNGALGQPYQ-EGAGELTLGTLGTMIGA---------FGN---PMRA  270 (380)
T ss_dssp             CSEEEEESCHHHHHHHHHHHHHTTCC--CCEEECGGGGSHHHH-HHHGGGGTTCEEEEECT---------TSS---SCCH
T ss_pred             CCEEEEEcCchHHHHHHHHHHHcCCC--CCEEEcchhcCHHHH-HHhhHhhCCeeEEeecc---------cCC---CCCh
Confidence            88887776666677888888887764  345554432211100 00011112221111000         000   0001


Q NP_000836.2     355 RNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRM  434 (908)
Q Consensus       355 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~  434 (908)
                      ....|.+.+.+.++......   .    ..       .........++..+|||+++++++++++..             
T Consensus       271 ~~~~f~~~~~~~~~~~~~~~---~----~~-------~~~~~~~~~~~~~~yda~~~~~~a~~~~~~-------------  323 (380)
T 4MPT_B          271 PAADFAKAYKAKYGTDRWWG---N----DP-------ENPQLFMAISVSNGYDAANILFEGIRLANS-------------  323 (380)
T ss_dssp             HHHHHHHHHHHHHCSCTTTC---S----CT-------TSCCTTHCCCCCHHHHHHHHHHHHHHHHTS-------------
T ss_pred             HHHHHHHHHHHHHCCCccCC---C----CC-------CCchhhhhHHHHHHHHHHHHHHHHHHHcCC-------------
Confidence            11223333332221100000   0    00       000000012367899999999999987642             


Q NP_000836.2     435 STIDGKELLGYIRAV-NFNGSAGTPVTFNENGDA---PGRYDIFQYQ  477 (908)
Q Consensus       435 ~~~~~~~l~~~l~~~-~f~G~~G~~v~Fd~~G~~---~~~~~i~~~~  477 (908)
                        .++..+.++|++. .|.|.+| ++.|+++|++   ...+.++++.
T Consensus       324 --~~~~~i~~~l~~~~~~~g~~g-~~~f~~~~~~~~~~~~~~v~~~~  367 (380)
T 4MPT_B          324 --TDPKAVIAAIESIKDYQGVNT-AYTFSKERHHGIETDGVKVFEYV  367 (380)
T ss_dssp             --CCHHHHHHHHTTCCSEECSSC-EECCCSSCCBCCCGGGEEEEEEE
T ss_pred             --CCHHHHHHHHHcCCCcccccc-eEEeecCcccccccceeEEEEEE
Confidence              1345677788765 7899888 8999986543   2356666665


No 119
>4ZPJ_A Extracellular ligand-binding receptor; ABC transporter, substrate-binding protein, DUF3597; HET: ZN, MSE; 2.24A {Sphaerobacter thermophilus (strain DSM 20745 / S 6022)}
Probab=99.37  E-value=5.1e-17  Score=177.05  Aligned_cols=346  Identities=19%  Similarity=0.206  Sum_probs=206.4  Template_Neff=11.500

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||++.|.++...          ..+.....+++.|++++|+.   ..|+++++.+.|+.+++..    ..+
T Consensus        48 ~~~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~---~~g~~~~l~~~d~~~~~~~----~~~  110 (423)
T 4ZPJ_A           48 SSASGEPIRIGVLLTLSGPQG----------VNGEGNLRGLTLALDQAGMQ---FGGRPVELIIEDSAGQPEQ----AIT  110 (423)
T ss_dssp             -----CCEEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHTTTE---ETTEEEEEEEEECTTCHHH----HHH
T ss_pred             cccCCCCEEEEEEECCCCCch----------hHhHHHHHHHHHHHHHhccc---cCCEEEEEEEEcCCCCHHH----HHH
Confidence            345677899999999875421          24567889999999999864   2367788888776655332    233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN--TRYDFFSRVV  196 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~--~~~~~~~~~~  196 (908)
                      .+++++.+                  +++++++++.++.....+...+...+||+|.+....+.+...  ..+++++++.
T Consensus       111 ~~~~l~~~------------------~~~~~iig~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~  172 (423)
T 4ZPJ_A          111 KTRQLIER------------------DRVHLIAGITLSNEAAAVRDILVQAEMPTIVTNAGLQALTRDPAMRSPYLFRVS  172 (423)
T ss_dssp             HHHHHHHT------------------SCCSEEEECCCHHHHHHHHHHHHHTTCCEEESSCCCTHHHHSTTTCCTTEEESS
T ss_pred             HHHHHHHh------------------cCCcEEEecCCcHHHHHHHHHHHHCCCCEEEccCCcHHHcCCcccCCCceEEee
Confidence            33433321                  468888888766555566777888999999987655433211  1256788888


Q NP_000836.2     197 PPDSYQAQAMVDIVT-ALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PN  274 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~-~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~  274 (908)
                      ++....++.+++++. +++|+++++++.++.++..+.+.|++.+++. ++++.....+.  ....+....+++++.. .+
T Consensus       173 ~~~~~~~~~~~~~l~~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~~~~~~~~~~~~~~~~~~~  249 (423)
T 4ZPJ_A          173 FANGQYDAPAADYAYETLGYRRMVLHAADYAAGHEEMAAFRSRFEQA-GGEIVDEVVAP--IGTQDFGPYLQRIEQAAAE  249 (423)
T ss_dssp             CCTTTTTHHHHHHHHHTTCCCEEEEEEESSHHHHHHHHHHHHHHHHT-TCEEEEEEEEC--TTCSCCHHHHHHHHHHGGG
T ss_pred             cCcccchHHHHHHHHHHhCCCEEEEEEeCcHHHHHHHHHHHHHHHHc-CCEEceEEecC--CCCCChHHHHHHHHHHHcC
Confidence            888888888888884 4589999999866667777788888888775 35544322222  1123344556666521 26


Q NP_000836.2     275 ARAVIMFA-NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANN  353 (908)
Q Consensus       275 ~~viv~~~-~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~  353 (908)
                      +++|++.. .+..+..+++++++.|+..++.+++.+.+...... ........+.+......          .   ....
T Consensus       250 ~~~ii~~~~~~~~~~~~~~~~~~~g~~~~~~ii~~~~~~~~~~~-~~~~~~~~~~~~~~~~~----------~---~~~~  315 (423)
T 4ZPJ_A          250 ADAVFAFHGTSTDAIRFLVQYQEFGLKDSIPLIPSGADVDQSIL-PEIGDAALGLVSGTLYT----------A---YNDT  315 (423)
T ss_dssp             CSEEEEECCSSHHHHHHHHHHHHTTCTTTSCEEECGGGGCTTTH-HHHGGGGTTCEEEESCC----------T---TCCS
T ss_pred             CCEEEEEcCChHHHHHHHHHHHHcCCCCCCcEecCCcccChhHH-HHHHHhhcceeEeeccc----------c---CCCC
Confidence            78887664 35567788888888887533455555433221100 00111122222111100          0   0001


Q NP_000836.2     354 RRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPR  433 (908)
Q Consensus       354 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~  433 (908)
                      +....|.+.|++.+..                          ..+..++..+||+++++++|+++....           
T Consensus       316 ~~~~~f~~~~~~~~~~--------------------------~~~~~~~~~~yda~~~l~~al~~~~~~-----------  358 (423)
T 4ZPJ_A          316 PESQEFVEAFTARHEG--------------------------ILPGLVDYAGYIGGRVIAEALTAIDGE-----------  358 (423)
T ss_dssp             HHHHHHHHHHHHHTTT--------------------------CCCCHHHHHHHHHHHHHHHHHHHTTTC-----------
T ss_pred             HHHHHHHHHHHHHhCC--------------------------CCCChhhHHHHHHHHHHHHHHHHcCCC-----------
Confidence            1112232222222110                          012345678999999999999886431           


Q NP_000836.2     434 MSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQY  476 (908)
Q Consensus       434 ~~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~  476 (908)
                        ..+++.+.+.|++..|.|.+| ++.|+++|++. ..+.++++
T Consensus       359 --~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~~~~~  399 (423)
T 4ZPJ_A          359 --VENKEALLEALKAVEFTGPAG-NFRFHPESQGPVTTILLCRV  399 (423)
T ss_dssp             --TTCHHHHHHHHHHCEEEETTE-EEEECTTTCSEEEEEEEEEE
T ss_pred             --CCCHHHHHHHHHcCCcccCCe-eEEECCCCCCceeeEEEEEE
Confidence              124556778888888999988 89999887653 33444433


No 120
>6DLZ_B Glutamate receptor 2,Voltage-dependent calcium channel; Ion channel, TRANSPORT PROTEIN; HET: GLU, CYZ; 3.9A {Rattus norvegicus}
Probab=99.37  E-value=5.2e-17  Score=198.52  Aligned_cols=356  Identities=15%  Similarity=0.186  Sum_probs=226.0  Template_Neff=11.100

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~~~~  122 (908)
                      ++++||+++|.++.                ....|++.|++++|++     |+++++...|+. +++..    +.+.+++
T Consensus         1 ~~i~IG~~~~~~~~----------------~~~~g~~~A~~~iN~~-----g~~i~l~~~d~~~~~~~~----a~~~~~~   55 (1031)
T 6DLZ_B            1 NSIQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSFA----VTNAFCS   55 (1031)
T ss_dssp             CCEEEEEEECTTCH----------------HHHHHHHHHHHHSCCS-----SCCEEEEEEECCSSCHHH----HHHHHHH
T ss_pred             CceeeeeeeCCCCh----------------HHHHHHHHHHHHhhcC-----CceeccceEecCCCCHHH----HHHHHHH
Confidence            36899999998642                4678999999999985     477888888876 44322    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   +++++++|+.++....+++..+...++|++++..++.     ..+++++++.|+.   
T Consensus        56 l~~-------------------~~v~aviG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~~---  108 (1031)
T 6DLZ_B           56 QFS-------------------RGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPDL---  108 (1031)
T ss_dssp             HHH-------------------HTCSCEEECCCTTTHHHHHHHHHHHCCCEEECSSCCS-----SCCTTEEECSCCC---
T ss_pred             HHh-------------------cCeeEEEecCChHHHHHHHHHHhccCCcEEEcCCCCC-----CCCCeEEEeeccH---
Confidence            332                   5799999998887777888889999999998875433     2478899998873   


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPR--EPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      +.++++++++++|+++++++ +++++....+.+.+.+++. ++++.....+..  +.+..++.+.++++++ .++|+|++
T Consensus       109 ~~~~~~~l~~~~~~~v~ii~-~~~~g~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~d~~~~~~~i~~-~~~~~vv~  185 (1031)
T 6DLZ_B          109 KGALLSLIEYYQWDKFAYLY-DSDRGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKERRVIL  185 (1031)
T ss_dssp             HHHHHHHHHHHTCSEEEEEE-CGGGCSHHHHHHHHHHHHT-TCEEEEEECTTCCSTTTTTHHHHHHHHHTT-TTCCEEEE
T ss_pred             HHHHHHHHHHhCCCEEEEEE-eCcchHHHHHHHHHHHhhc-CCeEEEEEecCCCCCCCcchhHHHHHHHcc-cCceEEEE
Confidence            67778888888999999999 6678887788888877765 455543332210  0123456677777764 57899988


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      ......+..+++++++.|+.. .+.|+..+........ ........+.......               ....+....+
T Consensus       186 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~---------------~~~~~~~~~f  249 (1031)
T 6DLZ_B          186 DCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGAEVSGFQIV---------------DYDDSLVSKF  249 (1031)
T ss_dssp             ECCHHHHHHHHHHHHHHTCCSTTCEEEECSSBTTTSCC-SSSSSSSCEEEEEESC---------------CTTSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHhCCccCCcEEEEEeCCCCcCcH-HHhccCCceEEEEEEe---------------eCCcHHHHHH
Confidence            877777888999999988854 3566665422211100 0000111111111000               0001112223


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~~~~-  434 (908)
                      .+.+++.++.....             .      ....++.++..+||+++++++|++++......    .....|... 
T Consensus       250 ~~~~~~~~~~~~~~-------------~------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~~~~~~  310 (1031)
T 6DLZ_B          250 IERWSTLEEKEYPG-------------A------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANP  310 (1031)
T ss_dssp             HHHHHTSCTTTSTT-------------C------SSSCCCHHHHHHHHHHHHHHHHHHHHHHTTCCCCCCSCCCCTTCTT
T ss_pred             HHHHHhcccccCCC-------------C------CcCCCcHHHHHHHHHHHHHHHHHHHHHHcccccccCCCCCCCccCC
Confidence            33333322210000             0      00123456788999999999999998653210    000112110 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                        ...+++.+.++|++..|.|..| ++.|+++|++.. .+.+++++    ++.+..+|.|+..
T Consensus       311 ~~~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~g~~~~~~~~i~~~~----~~~~~~~~~~~~~  368 (1031)
T 6DLZ_B          311 AVPWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEV  368 (1031)
T ss_dssp             CCCCTHHHHHHHHHTTCCCEETTE-ECEECSSSCEESCEEEEEEEC----SSCEEEEEEEESS
T ss_pred             CCCcccHHHHHHHHHhcCccCCCc-cEEeCCCCcEEeeEEEEEEec----cCCcEEEEEEeCC
Confidence              1224667888888888999888 899999888764 78888887    3568888888754


No 121
>3EAF_A ABC transporter, substrate binding protein; 11229a2, PSI2, NYSGXRC, ABC transporter; 2.0A {Aeropyrum pernix}
Probab=99.36  E-value=6.6e-17  Score=173.99  Aligned_cols=362  Identities=14%  Similarity=0.105  Sum_probs=213.9  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLL-SNI--TLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il-~g~--~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      .++++||+++|.++..          ...+.....|++.|++++|..++++ +|+  ++++.+.|+.+++.    ...+.
T Consensus         2 ~~~~~Ig~i~~~~~~~----------~~~~~~~~~g~~~a~~~~n~~g~~~~~g~~~~v~~~~~d~~~~~~----~~~~~   67 (391)
T 3EAF_A            2 SLTINVGLLVDETGPT----------SDVGKGYSLGAELAFKYFNEKGIYTKDGVRVNINYIKRDYAYNPT----TAEEY   67 (391)
T ss_dssp             CEEEEEEEEECSSSTT----------HHHHHHHHHHHHHHHHHHHHHCEECTTCCEEEEEEEEEECTTCHH----HHHHH
T ss_pred             CCeEEEEEEecCCCCc----------chhchhhHHHHHHHHHHHHhcCceeeCCceeEEEEEEecCCCCHH----HHHHH
Confidence            4578999999976532          1356678899999999999765432 344  56666677655432    22333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++++.                  +.++++||++ ++.....+...+...++|+|.+....+.+    .+++++++.+++
T Consensus        68 ~~~l~~------------------~~~v~~ii~~-~~~~~~~~~~~~~~~~ip~i~~~~~~~~~----~~~~~~~~~~~~  124 (391)
T 3EAF_A           68 YREFRD------------------RYGVIAIIGW-GTADTEKLSDQVDTDKITYISASYSAKLL----VKPFNFYPAPDY  124 (391)
T ss_dssp             HHCCCC------------------CTCCSEEEEC-CHHHHHHHHHHHHHHTCEEEESCCCGGGT----TSTTEECSSCCH
T ss_pred             HHHHHH------------------hcCceEEEec-ccHHHHHHHHHHHHcCCeEEEcCcchhhc----CCCceeecCCCH
Confidence            333332                  1478999986 55555566677888999999987654322    246778888888


Q NP_000836.2     200 SYQAQAMVDIV-TALGWNYVSTLAS-EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       200 ~~~~~~~~~~l-~~~~~~~v~ii~~-~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ...+..+++++ ++++|+++++++. ++.++..+.+.|++.+++. ++++.....+.......+....+++++. .++++
T Consensus       125 ~~~~~~~~~~l~~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~  202 (391)
T 3EAF_A          125 STQACSGLAFLASEFGQGKLALAYDSKVAYSRSPIGAIKKAAPSL-GLQVVGDYDLPLRATEADAERIAREMLA-ADPDY  202 (391)
T ss_dssp             HHHHHHHHHHHHHHHCSEEEEEEECTTCHHHHTTHHHHHHHTGGG-TEEEEEEEECCTTCCHHHHHHHHHHHHT-TCCSE
T ss_pred             HHHHHHHHHHHHHHhCCCeEEEEEcCCCccccCHHHHHHHHHHHc-CCEEEEeeecCCCCCcccHHHHHHHHHH-cCCCE
Confidence            88888888887 5679999999985 5566777788888887765 3554332111110112334555666653 47888


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTI-LPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      +++...+..+..+++++++.|+.  .+|+..+ |...............+.+.. ...          .........+..
T Consensus       203 vi~~~~~~~~~~~~~~~~~~g~~--~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~----------~~~~~~~~~~~~  269 (391)
T 3EAF_A          203 VWCGNTISSCSLLGRAMAKVGLD--AFLLTNV-WGFDERSPQLIGEGGYGKVFGISPF----------IYPMFGQDVEGI  269 (391)
T ss_dssp             EEECSCHHHHHHHHHHHHHHTCC--CEEEECG-GGCSTTHHHHHCGGGTTSEEEEESB----------CCGGGCTTCHHH
T ss_pred             EEECCCHHHHHHHHHHHHHcCCC--cEEEecc-ccCCccchHHhccccccceeeeecc----------ccccCCcCCHHH
Confidence            87765666777889999888874  3455443 221110000001111221110 000          000000001111


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMST  436 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~  436 (908)
                      ..|.+.+++ +...                        ...+..++..+||+++++++|++++.....          ..
T Consensus       270 ~~f~~~~~~-~~~~------------------------~~~~~~~~~~~yda~~~~~~al~~~~~~~~----------~~  314 (391)
T 3EAF_A          270 QTIFEAARM-NGVS------------------------EDQINLRVVQGFVNVWLLIKAIESVTSQDL----------QE  314 (391)
T ss_dssp             HHHHHHHHH-TTCC------------------------GGGCCHHHHHHHHHHHHHHHHHTTSCHHHH----------HH
T ss_pred             HHHHHHHHH-cCCC------------------------cccCChhHHHHHHHHHHHHHHHHHhccccc----------cc
Confidence            122222222 1100                        011235677899999999999998753210          01


Q NP_000836.2     437 IDGKELLGYIRAVNFN--GSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       437 ~~~~~l~~~l~~~~f~--G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      .+++.+.++|++..|.  |.+|+++.|+++|++. ..+.+.+++.   ++.++.++.|...
T Consensus       315 ~~~~~l~~~l~~~~~~~~G~~g~~i~f~~~~~~~~~~~~i~~~~~---~~~~~~v~~~~~~  372 (391)
T 3EAF_A          315 RGGEALKEALEANTFDLGGITADTIDYEPGFHLAYRKVFIIKLGE---NGELQLMGKFEAP  372 (391)
T ss_dssp             HTHHHHHHHHHHCCBCSTTCBSSCBCCBTTBCCCCCCEEEEEECT---TSSEEEEEEECCC
T ss_pred             cChHHHHHHHHhCCCCCCCccccceEecCCCccccceEEEEEECC---CCeEEeCcceeCc
Confidence            2456778888877787  7765469999877653 4566666652   2467888888754


No 122
>5UOW_C N-methyl-D-aspartate receptor subunit NR1-8a, N-methyl-D-aspartate; membrane protein; HET: NAG, GLU, BMK; 4.5A {Xenopus laevis}
Probab=99.36  E-value=6.8e-17  Score=192.22  Aligned_cols=336  Identities=18%  Similarity=0.285  Sum_probs=221.7  Template_Neff=11.300

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.+                  ....|++.|++++|+++   .+.++++.+.|+..++.. ...+.+.+++
T Consensus         2 ~~~i~Ig~~~p~~------------------~~~~~~~~a~~~~n~~g---~~~~i~l~~~d~~~~~~~-~~~~~~~~~~   59 (814)
T 5UOW_C            2 PKIVNIGAVLSTK------------------KHEQIFREAVNQANKRH---FTRKIQLNATSVTHRPNA-IQMALSVCED   59 (814)
T ss_dssp             CSCEEEEEEESCH------------------HHHHHHHHHHHHHHHHS---CTTTCCEEEEEEECCSSH-HHHHHCCCCC
T ss_pred             CCccceEEEecCc------------------hHHHHHHHHHHHHHHhc---cCCCeeeeceeecCCCCH-HHHHHHHHHH
Confidence            4678999999865                  24578999999999865   246677777776544322 1112333333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-----IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-----~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      +..                   +++++++|+.++..+     ..++..+...++|++++.+..+.+.+...+++++++.+
T Consensus        60 l~~-------------------~~v~~iig~~~~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~l~~~~~~~~~~~~~~  120 (814)
T 5UOW_C           60 LIS-------------------SQVYAILVSHPPAPTDHLTPTPISYTAGFYRIPVIGLTTRMSIYSDKSIHLSFLRTVP  120 (814)
T ss_dssp             TTT-------------------TCCSCEEECCCSSCCSSCTTSHHHHHHHHHTCCEEESSCCCGGGCCTTTCSSEEESSC
T ss_pred             HHh-------------------cCceEEEEcCCCCCCCCCCCchhHHhhhhcCCCEEEccCCCccccCCccCchhhcCCC
Confidence            322                   478899998877766     56667888899999998876665544335788999999


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARA  277 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v  277 (908)
                      ++...++++++++++++|+++++++.+++++....+.+++.+++. ++++.....+.  .+..++...++++++ .++|+
T Consensus       121 ~~~~~~~~~~~~~~~~~~~~i~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~l~~-~~~~~  196 (814)
T 5UOW_C          121 PYSHQALVWFEMMRLFNWNHVILIVSDDHEGRAAQKKLETLLEEK-ESKADKVLQFE--PGTKNLTALLLEAKE-LEARV  196 (814)
T ss_dssp             CTTTHHHHHHHHHHHHTCCCCEEEEESSHHHHHHHHHHHHHHHHS-SCCCSCEEEEC--SSCSCCHHHHHHHHH-SSCCE
T ss_pred             CHHHHHHHHHHHHHHcCCcEEEEEEecCcchHHHHHHHHHHHHhc-ccccceeeccC--CCCccHHHHHHHHHh-cCCeE
Confidence            999999999999988899999999987788888888888888775 45554333232  223456667777763 57899


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRN  356 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  356 (908)
                      |++.+.......+++++++.|+.. .+.|++.+.+....    .......+.+..                         
T Consensus       197 vv~~~~~~~~~~~l~~~~~~g~~~~~~~~~~~~~~~~~~----~~~~~~~~~~~~-------------------------  247 (814)
T 5UOW_C          197 IILSASEDDATAVYKSAAMLDMTGAGYVWLVGEREISGS----ALRYAPDGIIGL-------------------------  247 (814)
T ss_dssp             EEEECCHHHHHHHHHHHHHTTTTSTTCEEEECHHHHSTH----HHHTCCTTCEEE-------------------------
T ss_pred             EEEeCCHHHHHHHHHHHHhcCCCCCCeEEEEecCCCCCc----hhhcCCCceEEE-------------------------
Confidence            888877777788899988888753 34555543221110    000000000000                         


Q NP_000836.2     357 VWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGY-IGLCPRM-  434 (908)
Q Consensus       357 ~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~-~~~~~~~-  434 (908)
                          .    .                             ..+..++..+|||++++++++++.....+... ...|... 
T Consensus       248 ----~----~-----------------------------~~~~~~~~~~yda~~~~~~a~~~~~~~~~~~~~~~~~~~~~  290 (814)
T 5UOW_C          248 ----Q----L-----------------------------INGKNESAHISDAVAVVAQAIHELFEMEQITDPPRGCVGNT  290 (814)
T ss_dssp             ----E----E-----------------------------SSSSCHHHHHHHHHHHHHHHHHHHTTSCCCCCCCSSSTTCC
T ss_pred             ----E----e-----------------------------cCCCcchhHHHHHHHHHHHHHHHHHhcCCCCCCCCCcCCCC
Confidence                0    0                             00123456789999999999998765422110 0112111 


Q NP_000836.2     435 -STIDGKELLGYIRAV-NFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       435 -~~~~~~~l~~~l~~~-~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                       ...++..+.+.+++. .|+|.+| ++.||++|++. ..+.+.+++    ++.+..+|.|+..
T Consensus       291 ~~~~~~~~l~~~l~~~~~~~G~~g-~~~fd~~g~~~~~~~~i~~~~----~~~~~~v~~~~~~  348 (814)
T 5UOW_C          291 NIWKTGPLFKRVLMSSKYPDGVTG-RIEFNEDGDRKFAQYSIMNLQ----NRKLVQVGIFDGS  348 (814)
T ss_dssp             SCCSSSHHHHHHHHTCCCCCCSSC-CCCBCTTSCBCCCCEEEEECC----TTSCEEEEEECSS
T ss_pred             ccccchHHHHHHHHhcCCCCCccc-ceEECCCCceeeeEEEEEEcc----CCceEEEEEEeCC
Confidence             012445677777754 6788888 89999999875 678888886    3578999999864


No 123
>3LOP_A Substrate binding periplasmic protein; Substrate-binding, Protein Structure Initiative II(PSI; HET: EDO; 1.55A {Ralstonia solanacearum}
Probab=99.36  E-value=7.1e-17  Score=171.86  Aligned_cols=352  Identities=11%  Similarity=0.091  Sum_probs=207.6  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||+++|.++...          ..+.....+++.|++++|+++++. |+++++...|+.+++.    ...+.+++
T Consensus         3 ~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~n~~g~~~-g~~v~~~~~d~~~~~~----~~~~~~~~   67 (364)
T 3LOP_A            3 LADISVIQSLPLSGSQA----------VTGRALNAGARLYFDWLNLNGGIN-GETIRLVARDDEQKIE----QTVRNVRD   67 (364)
T ss_dssp             --CEEEEEEECSSSTTH----------HHHHHHHHHHHHHHHHHHHTTTBT-TBCEEEEEEECTTCHH----HHHHHHHH
T ss_pred             cccEEEEEecCCCCCch----------HHhHHHHHHHHHHHHHHHHcCCcC-CEEEEEEEecCCCCHH----HHHHHHHH
Confidence            46789999999865321          245678899999999999876543 6778887777655532    22333333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVA--NILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va--~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++.                  ..++++++++.++.......  ..+...++|+|.++...+.+.   ..++++++.++..
T Consensus        68 l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~---~~~~~~~~~~~~~  126 (364)
T 3LOP_A           68 MAR------------------VDNPVALLTVVGTANVEALMREGVLAEARLPLVGPATGASSMT---TDPLVFPIKASYQ  126 (364)
T ss_dssp             HHH------------------HSCEEEEECCCCHHHHHHHHHTTHHHHHTCCEESCSCCCGGGG---SCTTEECCSCCHH
T ss_pred             HHh------------------hcCceEEEEecCCHHHHHHHhhhhHHhcCCCEEeccCCCcccC---CCCceEEccCCHH
Confidence            332                  14788888876655444443  567788999998876554332   1467788888888


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      ..++.+++++.+.+|++|++++.++.++..+.+.+++.+++. ++++.....+.  ....+....+++++. .++++|++
T Consensus       127 ~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii~  202 (364)
T 3LOP_A          127 QEIDKMITALVTIGVTRIGVLYQEDALGKEAITGVERTLKAH-ALAITAMASYP--RNTANVGPAVDKLLA-ADVQAIFL  202 (364)
T ss_dssp             HHHHHHHHHHHHTTCCCEEEEEETTHHHHHHHHHHHHHHHTT-TCCCSEEEEEC--TTSCCCHHHHHHHHH-SCCSEEEE
T ss_pred             HHHHHHHHHHHHhCCCEEEEEEecCchhHHHHHHHHHHHHHC-CCceeEEeeeC--CCCCChHHHHHHHHh-CCCCEEEE
Confidence            888889998877899999999966667777888888888775 35544322221  122344555666653 47888777


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQE-EIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~-~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      ...+..+..+++++++.|+.  ..+++.+.+...... .... ....+.......           ........+....|
T Consensus       203 ~~~~~~~~~~~~~~~~~g~~--~~ii~~~~~~~~~~~-~~~~~~~~~~~~~~~~~-----------~~~~~~~~~~~~~f  268 (364)
T 3LOP_A          203 GATAEPAAQFVRQYRARGGE--AQLLGLSSIDPGILQ-KVAGLDAVRGYSLALVM-----------PNPGKSVNPVIREF  268 (364)
T ss_dssp             ESCHHHHHHHHHHHHHTTCC--CEEEECTTSCHHHHH-HHHCHHHHTTCEEEECS-----------CCTTCTTSHHHHHH
T ss_pred             ECCHHHHHHHHHHHHHCCCC--ceEEEecCCChHHHH-HHhCccccccEEEEEEe-----------cCCCcCCCHHHHHH
Confidence            76566677888888887773  456665543321110 0000 011221110000           00000001111223


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDG  439 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~  439 (908)
                      .+.+++.+..                         ...++.++..+||++++++.|+++....              .++
T Consensus       269 ~~~~~~~~~~-------------------------~~~~~~~~~~~yda~~~~~~a~~~~~~~--------------~~~  309 (364)
T 3LOP_A          269 NRARAAVGAK-------------------------DVDLSFRAVEGFVAAKVLAEAIRRAGPK--------------PTR  309 (364)
T ss_dssp             HHHHHHHTCT-------------------------TCCCCHHHHHHHHHHHHHHHHHHHHCSS--------------CCH
T ss_pred             HHHHHHhCCC-------------------------CCCCCHHHHHHHHHHHHHHHHHHHHCCC--------------CCH
Confidence            3222221110                         0112345778999999999999886421              234


Q NP_000836.2     440 KELLGYIRAV-NFNGS-AGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWT  492 (908)
Q Consensus       440 ~~l~~~l~~~-~f~G~-~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~  492 (908)
                      +.+.++|++. .|... .+ ++.|++++++. ..+.+++++    .+.++.++.|+
T Consensus       310 ~~~~~~l~~~~~~~~~g~~-~~~f~~~~~~~~~~~~~~~~~----~~~~~~~~~~~  360 (364)
T 3LOP_A          310 EQVRHALTELRDYDVGGGF-TVDFTDRSRPGSHYIELGVVG----PNGLVIQEGHH  360 (364)
T ss_dssp             HHHHHHHHTCEEEESSTTC-EEECSSTTSCSCCCCEEEEEC----TTSCEEEC---
T ss_pred             HHHHHHHHhCCCCcCCCCe-eeecCCCCCcccCeEEEEEEC----CCceEeecCCC
Confidence            5677777664 46421 23 68888766543 456666666    24566677665


No 124
>5IOV_B GluN1, GLY-GLY-GLU-GLU; ligand-gated ion channel, synaptic transmission; HET: QEM, GLU, GLY; 7.5A {Xenopus laevis}
Probab=99.35  E-value=7.4e-17  Score=192.20  Aligned_cols=341  Identities=15%  Similarity=0.193  Sum_probs=215.4  Template_Neff=11.300

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPD--LLSNITLGVRILDTCSRDTYALEQS  116 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~--il~g~~l~~~~~d~~~~~~~a~~~~  116 (908)
                      .....++++||+++|.++             .         ++|++++|++++  .+++..+.+.+.|+.+++..+.+  
T Consensus        23 ~~~~~~~i~Ig~~~~~~g-------------~---------~~A~~~iN~~~g~~~~~~~~~~~~~~d~~~~~~~~~~--   78 (825)
T 5IOV_B           23 YAQKHPNMDIAVILVGTT-------------E---------EVAIKDVHEKDDFHHLPVTPRVELVTMQESDPKSIIT--   78 (825)
T ss_pred             HHhhCCCCcEEEEEecCc-------------e---------eeeecccccCCCcccCCCCceeeEecCCCCCHHHHHH--
Confidence            356678999999999763             1         889999998876  44454455555666655443333  


Q NP_000836.2     117 LTFVQALIEKDASDVKCANGDPPIFTKPDKISGVI-GAAASS--VSIMVANILRLFKIPQISYASTAPE-LSDNTRYDFF  192 (908)
Q Consensus       117 ~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~--~~~~va~~~~~~~iP~Is~~~~~~~-l~~~~~~~~~  192 (908)
                        .+++++.                  .+++++++ |+.++.  .+..++..+...++|+|++.+..+. +++...++++
T Consensus        79 --~~~~l~~------------------~~~v~avi~G~~~s~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~  138 (825)
T 5IOV_B           79 --RICDLMS------------------DKKVQGVVFGDDTDQEAIAQILDFISVQTLTPILGIHGGSSMIMADKEEASMF  138 (825)
T ss_pred             --HHHHhcc------------------cCCcEEEEEcCCCChHHHHHHHHHHHHhhCCCEEEecCCCccccccccCCeeE
Confidence              3333332                  14788876 987765  4456667777899999996544332 2222357889


Q NP_000836.2     193 SRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREP-RPGEFEKIIKRLLE  271 (908)
Q Consensus       193 ~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~-~~~~~~~~~~~l~~  271 (908)
                      +++.|++...+.++++++.+++|+++++++.+++++....+.+++.+++. +.++.....+..+. ...+....++++++
T Consensus       139 ~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~~~  217 (825)
T 5IOV_B          139 FQFGPSIEQQASVMLNIMEEYDWYIFSIVTTYFPGYQDFENKVRSTIENS-FVGWELEEVIHLDMSLDDIDSKIQNQLKK  217 (825)
T ss_pred             EEcCCCHHHHHHHHHHHHHHcCCeEEEEEEEcCCCchhHHHHHHHHHHhc-cCceEEEEEEEccCChhhHHHHHHHHHHh
Confidence            99999998889999999988899999999987778888888888877764 34443222221100 12234455555653


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTL  350 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~  350 (908)
                       .++|+|++.+....+..+++++++.|+.. ++.|+..+.+......  .......+..                     
T Consensus       218 -~~~~~iv~~~~~~~~~~~l~~~~~~g~~~~~~~~i~~~~~~~~~~~--~~~~~~~~~~---------------------  273 (825)
T 5IOV_B          218 -LQSPVILLYCTKEEATYIFEVAHSVGLTGYGFTWIVPSLVAGDTDT--VPDEFPTGLI---------------------  273 (825)
T ss_pred             -cCCCEEEEECCHHHHHHHHHHHHHcCCCCCCeEEEeeecCCCCCCC--CCCcCCCCeE---------------------
Confidence             47899888777777888999998888753 3456654432211000  0000000000                     


Q NP_000836.2     351 ANNRRNVWFAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPG--YI  428 (908)
Q Consensus       351 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~--~~  428 (908)
                              ..     .+.                           ..+..++..+|||++++++|++++....+..  ..
T Consensus       274 --------~~-----~~~---------------------------~~~~~~~~~~yDav~~~a~al~~~~~~~~~~~~~~  313 (825)
T 5IOV_B          274 --------SV-----SYD---------------------------EWDYDLPARVRDGIAIITTAASTMLSEHNSIPQSK  313 (825)
T ss_pred             --------EE-----Eee---------------------------cCCCCcchhHHHHHHHHHHHHHHHHHhcCCCCCCC
Confidence                    00     000                           0012346789999999999999986542110  00


Q NP_000836.2     429 GLCPRM---STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAP-GRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       429 ~~~~~~---~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~-~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      ..|...   ...++..+.+.|++.+|.|  | ++.|+++|++. ..+.+++++.   ++.+..+|.|...
T Consensus       314 ~~~~~~~~~~~~~~~~l~~~l~~~~f~G--G-~~~f~~~g~~~~~~~~i~~~~~---~~~~~~~~~~~~~  377 (825)
T 5IOV_B          314 SSCNNIQESRVYEAHMLKRYLINVTFEG--R-DLSFSEDGYQMHPKLVIILLNQ---ERKWERVGKYKDR  377 (825)
T ss_pred             cccccCCcchhHhHHHHHHHHhcccccC--c-ceeeCCCCccceeeEEEEEeCC---CCceEEEEEEeCC
Confidence            122211   1124567888888889988  7 89999999884 5778888863   2568888888654


No 125
>5WEO_A Glutamate receptor 2,Voltage-dependent calcium channel; Ion channel, TRANSPORT PROTEIN; HET: CYZ, GLU;{Rattus norvegicus}
Probab=99.33  E-value=1.3e-16  Score=194.97  Aligned_cols=356  Identities=15%  Similarity=0.187  Sum_probs=224.0  Template_Neff=11.100

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~~~~  122 (908)
                      ++++||+++|.++.                ....|++.|++++|++     |+++++...|+. +++..    +.+.+++
T Consensus         1 ~~i~Ig~~~~~sg~----------------~~~~~~~~a~~~iN~~-----g~~l~~~~~d~~~~~~~~----a~~~~~~   55 (1034)
T 5WEO_A            1 NSIQIGGLFPRGAD----------------QEYSAFRVGMVQFSTS-----EFRLTPHIDNLEVANSFA----VTNAFCS   55 (1034)
T ss_dssp             CEEEEEEEECTTCH----------------HHHHHHHHHHHHHCCS-----SSEEEEEEEECCSSCHHH----HHHHHHH
T ss_pred             CceeeeeeecCCCh----------------HHHHHHHHHHHhhhcC-----CceeeeeeEecCCCCHHH----HHHHHHH
Confidence            36899999998752                5678999999999985     477888888876 44332    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      +++                   +++++++|+.++....+++..+.+.++|++++...++     ..+++++++.|+.   
T Consensus        56 l~~-------------------~~v~~viG~~~s~~~~~~~~~~~~~~ip~i~~~~~~~-----~~~~~~~~~~~~~---  108 (1034)
T 5WEO_A           56 QFS-------------------RGVYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTD-----GTHPFVIQMRPDL---  108 (1034)
T ss_dssp             HHH-------------------HTCSEEEECCCTTTHHHHHHHHHHHCCCEEECSSCCS-----SCCTTEEECCCCC---
T ss_pred             HHH-------------------cCeeEEEecCChHHHHHHHHHHcccCCeEEeCCCCCC-----CCCCeEEEecCch---
Confidence            332                   5789999998887777888888899999998875433     2468899998873   


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPR--EPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      +.++++++++++|+++++++ +++++....+.+.+.+++. ++++.....+..  +.+..++.+.++++++ .++|+|++
T Consensus       109 ~~~~~~~l~~~~~~~v~iv~-~~~~g~~~~~~~~~~~~~~-g~~v~~~~~~~~~~~~~~~d~~~~~~~i~~-~~~~~vv~  185 (1034)
T 5WEO_A          109 KGALLSLIEYYQWDKFAYLY-DSDRGLSTLQAVLDSAAEK-KWQVTAINVGNINNDKKDETYRSLFQDLEL-KKERRVIL  185 (1034)
T ss_dssp             HHHHHHHHHHHTCSEEEEEE-CGGGCSHHHHHHHHHHHHT-TCEEEEEECTTSCGGGTTHHHHHHHHHHTT-TTCCEEEE
T ss_pred             HHHHHHHHHHhCCCEEEEEE-eCCchHHHHHHHHHHHhhc-CCeEEEEEecCCCCCCCccchHHHHHHHhh-cCCcEEEE
Confidence            56777888788999999999 6677777777788777764 455543322210  0122456677777764 57899988


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQSG-HFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWF  359 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~~-~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  359 (908)
                      ......+..+++++++.|+.. .+.|++.+.+...... ........+.......               ....+....+
T Consensus       186 ~~~~~~~~~~~~~~~~~g~~~~~~~~i~~~~~~~~~~~-~~~~~~~~~~~~~~~~---------------~~~~~~~~~f  249 (1034)
T 5WEO_A          186 DCERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDL-LKIQFGGAEVSGFQIV---------------DYDDSLVSKF  249 (1034)
T ss_dssp             ESCHHHHHHHHHHHHHHTTTSTTCEEEECSSBTTSSCC-STTTTSSSEEEEEESS---------------CTTSHHHHHH
T ss_pred             eCCHHHHHHHHHHHHHhCCCcCCeEEEEEeCCCCCCch-HhcccCCceEEEEEEe---------------eCCcHHHHHH
Confidence            877777888999999988854 3556665422211100 0000001111111000               0011122223


Q NP_000836.2     360 AEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCP----GYIGLCPRM-  434 (908)
Q Consensus       360 ~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~----~~~~~~~~~-  434 (908)
                      .+.+++.++.....         .          ....++.++..+|||++++++|++++......    .....|... 
T Consensus       250 ~~~~~~~~~~~~~~---------~----------~~~~~~~~~~~~yda~~~~~~al~~~~~~~~~~~~~~~~~~~~~~~  310 (1034)
T 5WEO_A          250 IERWSTLEEKEYPG---------A----------HTATIKYTSALTYDAVQVMTEAFRNLRKQRIEISRRGNAGDCLANP  310 (1034)
T ss_dssp             HHHHHTSCTTTSTT---------C----------SSSSCCHHHHHHHHHHHHHHHHHHHHHHTTCCCCCCSCCCCTTCTT
T ss_pred             HHHHHhcccccCCC---------c----------CCCCCchHHHHHHHHHHHHHHHHHHHHHhccccccCCCCCCCccCC
Confidence            33333332210000         0          00123456788999999999999998643210    000112110 


Q NP_000836.2     435 --STIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPG-RYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       435 --~~~~~~~l~~~l~~~~f~G~~G~~v~Fd~~G~~~~-~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                        ...+++.+.+++++..|.|..| ++.|+++|++.. .+.+.+++    ++.+..+|.|...
T Consensus       311 ~~~~~~~~~l~~~l~~~~~~g~~G-~~~f~~~~~~~~~~~~i~~~~----~~~~~~~~~~~~~  368 (1034)
T 5WEO_A          311 AVPWGQGVEIERALKQVQVEGLSG-NIKFDQNGKRINYTINIMELK----TNGPRKIGYWSEV  368 (1034)
T ss_dssp             CCCCTHHHHHHHHHTTCCCEETTE-ECEECTTSCEESCEEEEEEEC----SSSEEEEEEEESS
T ss_pred             CCCcccHHHHHHHHHhcCcCCCCC-ceEeCCCCcEEeeEEEEEEec----cCCceEEEEEeCC
Confidence              1224667888888888999888 899998888754 67888887    3567888888753


No 126
>4DQD_A Extracellular ligand-binding receptor; structural genomics, PSI-Biology, protein structure; HET: PPY, PG4, GOL; 1.601A {Rhodopseudomonas palustris}
Probab=99.31  E-value=1.9e-16  Score=168.26  Aligned_cols=348  Identities=14%  Similarity=0.130  Sum_probs=203.5  Template_Neff=12.200

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||+++|.++...          ..+.....+++.+++++|       |.++++.+.|+..++..    ..+.+++
T Consensus         2 ~~~~~Ig~~~~~~~~~~----------~~~~~~~~g~~~a~~~~~-------g~~~~~~~~~~~~~~~~----~~~~~~~   60 (363)
T 4DQD_A            2 NAEIKIGITMSASGPGA----------ALGQPQSKTVAALPKEIG-------GEKVTYFALDDESDPTK----AAQNARK   60 (363)
T ss_dssp             -CCEEEEEEECCSSTTH----------HHHHHHHHHGGGSCSEET-------TEEEEEEEEECTTCHHH----HHHHHHH
T ss_pred             CcceEEEEEEcCCCCch----------hcChhhHHHHHHchHhhC-------CEEEEEEEEcCCCCHHH----HHHHHHH
Confidence            35789999999865321          245667888888888875       35577777776555332    2233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELS-DNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~-~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                  .++++++|++.++.....+...+...++|+|......+.+. .....++++++.++...
T Consensus        61 l~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~~~~~~~~~~~~~~~~~~  122 (363)
T 4DQD_A           61 LLS------------------EEKVDVLIGSSLTPVSLPLIDIAAEAKTPLMTMAAAAILVAPMDERRKWVYKVVPNDDI  122 (363)
T ss_dssp             HHH------------------TSCCSEEECCSSHHHHHHHHHHHHHTTCCEEECCCCGGGTCSCCTTGGGEEECSCCHHH
T ss_pred             HHh------------------hcCCCEEEecCCchhHHHHHHHHHHcCCCEEEccCccccccCcccccCceeEecCCHHH
Confidence            332                  14789999877665555666777888999998876554322 11134677888898888


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .++.+++++.+.+|+++++++.++.++..+.+.+++.+++. ++++.....+.  ....+....+++++. .++|++++.
T Consensus       123 ~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~i~~~  198 (363)
T 4DQD_A          123 MAEAIGKYIAKTGAKKVGYIGFSDAYGEGYYKVLAAAAPKL-GFELTTHEVYA--RSDASVTGQVLKIIA-TKPDAVFIA  198 (363)
T ss_dssp             HHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHH-TCEECCCEEEC--TTCSCCHHHHHHHHH-TCCSEEEEE
T ss_pred             HHHHHHHHHHHhCCCeEEEEEecCcchHHHHHHHHHHHHHc-CcEEeeeeeeC--CCCCccHHHHHHHHh-hCCCEEEEe
Confidence            88899999877799999999966667778888888888775 35544322222  112334555666653 578888877


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTL-ANNRRNVWFA  360 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~  360 (908)
                      .....+..+++++++.|+.  .+|++.+.+...... ........+.+.....      +......... ...+....|.
T Consensus       199 ~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~------~~~~~~~~~~~~~~~~~~~f~  269 (363)
T 4DQD_A          199 SAGTPAVLPQKALRERGFK--GAIYQTHGVATEEFI-KLGGKDVEGAIFAGEA------FSGAEDMPADSPFRKVKARFV  269 (363)
T ss_dssp             CCSGGGHHHHHHHHHTTCC--SEEECCGGGCSHHHH-HHHGGGGTTCEEEECH------HHHGGGSCTTCHHHHHHHHHH
T ss_pred             cCCccchHHHHHHHHcCCC--ceEEecccccCHHHH-HhhcccccccEEeccc------ccCCCCCCCCCchhHHHHHHH
Confidence            6555577888888888874  355555433322110 0001112232211100      0000000000 0000111122


Q NP_000836.2     361 EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGK  440 (908)
Q Consensus       361 ~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~  440 (908)
                      +.+++.++                          ...++.++..+||++++++.+++++.......        ...++.
T Consensus       270 ~~~~~~~~--------------------------~~~~~~~~~~~yda~~~~~~a~~~~~~~~~~~--------~~~~~~  315 (363)
T 4DQD_A          270 DAYKAANG--------------------------GAAPTIFGVHLWDSMTLVENAIPAALKAAKPG--------TPEFRA  315 (363)
T ss_dssp             HHHHHHTT--------------------------TCCCCTHHHHHHHHHHHHHHHHHHHHHHCCTT--------SHHHHH
T ss_pred             HHHHHHcC--------------------------CCCCCCccccHHHHHHHHHHHHHHHHHhcCCC--------CHHHHH
Confidence            22221110                          01234567889999999999998875431100        112455


Q NP_000836.2     441 ELLGYIRAV-NFNGSAGTPVTFNENG---DAPGRYDIFQYQ  477 (908)
Q Consensus       441 ~l~~~l~~~-~f~G~~G~~v~Fd~~G---~~~~~~~i~~~~  477 (908)
                      .+.+.|++. .|.|.+| .+.|+..+   .+...+.+++++
T Consensus       316 ~l~~~l~~~~~~~g~~g-~~~~~~~~~~~~~~~~~~i~~~~  355 (363)
T 4DQD_A          316 AIRDQIEKSKDLALNNG-LSNMTPDNHNGYDERSAFLIEIR  355 (363)
T ss_dssp             HHHHHHTTCCSEEETTE-EECCCSSCSSCCCGGGCEEEEEE
T ss_pred             HHHHHHHhcccccccCC-ccccCCCCCCCCCccceEEEEEE
Confidence            677888876 7888877 89997542   222356666665


No 127
>3SG0_A Extracellular ligand-binding receptor; structural genomics, PSI-Biology, protein structure; HET: 173, MSE; 1.201A {Rhodopseudomonas palustris}
Probab=99.28  E-value=3.9e-16  Score=167.41  Aligned_cols=350  Identities=14%  Similarity=0.122  Sum_probs=203.1  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||+++|.++...          ..+.....+++.+++++|       |+++++.+.|+.+++.    ...+.+
T Consensus        23 ~~~~~~~Ig~i~~~~~~~~----------~~~~~~~~g~~~a~~~~~-------g~~~~~~~~~~~~~~~----~~~~~~   81 (386)
T 3SG0_A           23 AAQAEIKIGITMSASGPGA----------ALGQPQSKTVAALPKEIG-------GEKVTYFALDDESDPT----KAAQNA   81 (386)
T ss_dssp             --CCCEEEEEEECCSSTTH----------HHHHHHHHHGGGSCSEET-------TEEEEEEEEECTTCHH----HHHHHH
T ss_pred             ccCCceEEEEEEcCCCCcc----------ccchhHHHHHHHcchhhC-------CEEEEEEEEcCCCCHH----HHHHHH
Confidence            4567899999999875321          245567788888888765       3456666667654432    223333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELS-DNTRYDFFSRVVPPD  199 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~-~~~~~~~~~~~~~~~  199 (908)
                      ++++.                  .++++++|++.++.....+...+...++|+|.+....+.+. .....++++++.+++
T Consensus        82 ~~~~~------------------~~~~~~ii~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~~~~~~~~~~~~~~~~~~~  143 (386)
T 3SG0_A           82 RKLLS------------------EEKVDVLIGSSLTPVSLPLIDIAAEAKTPLMTMAAAAILVAPMDERRKWVYKVVPND  143 (386)
T ss_dssp             HHHHH------------------TSCCSEEECCSSHHHHHHHHHHHHHTTCCEEECCCCGGGTCSCCTTGGGEEECSCCH
T ss_pred             HHHHh------------------cCCCCEEEccCCchhHHHHHHHHHHcCCCEEEcCCcccccCCcccccCceeEecCCH
Confidence            43332                  14788999877665555666777888999998876554322 111346788888888


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      ...++.+++++.+.+|++|++++.++.++..+.+.+++.+++. ++++.....+.  ....+....+++++. .++|+++
T Consensus       144 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~ii  219 (386)
T 3SG0_A          144 DIMAEAIGKYIAKTGAKKVGYIGFSDAYGEGYYKVLAAAAPKL-GFELTTHEVYA--RSDASVTGQVLKIIA-TKPDAVF  219 (386)
T ss_dssp             HHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHH-TCEECCCEEEC--TTCSCCHHHHHHHHH-TCCSEEE
T ss_pred             HHHHHHHHHHHHHhCCCEEEEEeecCccchhHHHHHHHHHHHc-CCEEeeeEeeC--CCCCChHHHHHHHHh-hCCCEEE
Confidence            8888899999877799999999966667778888888888775 35543322221  122345556666663 4788887


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTL-ANNRRNVW  358 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~  358 (908)
                      +......+..+++++++.|+.  ..|++.+.+...... ........+.+.....      +......... ...+....
T Consensus       220 ~~~~~~~~~~~~~~~~~~g~~--~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~------~~~~~~~~~~~~~~~~~~~  290 (386)
T 3SG0_A          220 IASAGTPAVLPQKALRERGFK--GAIYQTHGVATEEFI-KLGGKDVEGAIFAGEA------FSGAEDMPADSPFRKVKAR  290 (386)
T ss_dssp             EECCSGGGHHHHHHHHHTTCC--SEEECCGGGCSHHHH-HHHGGGGTTCEEEECH------HHHGGGSCTTCHHHHHHHH
T ss_pred             EecCCccchHHHHHHHHcCCC--ceEEeccccCCHHHH-HhhccccCccEEeecc------cCCCCCCCCCCchhHHHHH
Confidence            776555577888888888874  355555433221110 0001112222211100      0000000000 00001111


Q NP_000836.2     359 FAEFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTID  438 (908)
Q Consensus       359 ~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~  438 (908)
                      |.+.+.+.+.                          ...+..++..+||++++++++++++......        ....+
T Consensus       291 f~~~~~~~~~--------------------------~~~~~~~~~~~yda~~~~~~a~~~~~~~~~~--------~~~~~  336 (386)
T 3SG0_A          291 FVDAYKAANG--------------------------GAAPTIFGVHLWDSMTLVENAIPAALKAAKP--------GTPEF  336 (386)
T ss_dssp             HHHHHHHHTT--------------------------TCCCCHHHHHHHHHHHHHHHHHHHHHHHCCT--------TSHHH
T ss_pred             HHHHHHHHhC--------------------------CCCCCCcchhHHHHHHHHHHHHHHHHHhcCC--------CCHHH
Confidence            2221211110                          0113356788999999999999887542110        01124


Q NP_000836.2     439 GKELLGYIRAV-NFNGSAGTPVTFNENG---DAPGRYDIFQYQ  477 (908)
Q Consensus       439 ~~~l~~~l~~~-~f~G~~G~~v~Fd~~G---~~~~~~~i~~~~  477 (908)
                      ++.+.++|++. .|.|.+| .+.|+..+   .+...+.+.+++
T Consensus       337 ~~~l~~~l~~~~~~~g~~g-~~~~~~~~~~~~~~~~~~v~~~~  378 (386)
T 3SG0_A          337 RAAIRDQIEKSKDLALNNG-LSNMTPDNHNGYDERSAFLIEIR  378 (386)
T ss_dssp             HHHHHHHHTTCCSEEETTE-EECCCSSCSSCCCGGGCEEEEEE
T ss_pred             HHHHHHHHHhCcCccCCCC-ccccCCCCCCCccccceEEEEEe
Confidence            56677888876 7888877 89997542   222355666665


No 128
>5ERE_A Extracellular ligand-binding receptor; Solute Binding Protein, Tandem PAS; HET: MSE; 2.0A {Desulfohalobium retbaense DSM 5692}
Probab=99.27  E-value=4.6e-16  Score=176.57  Aligned_cols=327  Identities=15%  Similarity=0.220  Sum_probs=209.8  Template_Neff=12.000

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      .++||+++|.++...          ..+.....|++.|++++|        .++++.+.|+++++..+.    +.+++++
T Consensus         1 ~i~ig~~~p~~g~~~----------~~~~~~~~g~~~a~~~~g--------~~v~~~~~d~~~~~~~~~----~~~~~l~   58 (568)
T 5ERE_A            1 KPVVGVILPFSSAFE----------DIAVEQQRAVELALAESG--------SAFEIVFKDGGADVDTAV----QAFQDLV   58 (568)
T ss_dssp             CCEEEEEECCSSTTH----------HHHHHHHHHHHHHHHHHT--------CSSEEEEEECCSSHHHHH----HHHHHHH
T ss_pred             CCEEEEEeCCCCCcH----------HHHHHHHHHHHHHHHHcC--------CcEEEEEEcCCCCHHHHH----HHHHHHH
Confidence            378999999987531          356778899999999874        457778888877654332    3333333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .+                 +++++++++ .++..+..++..+...++|+|.+.+..+.+.+   .++++++.++....+.
T Consensus        59 ~~-----------------~~~~~~i~~-~~s~~~~~~~~~~~~~~ip~i~~~~~~~~~~~---~~~~~~~~~~~~~~~~  117 (568)
T 5ERE_A           59 RS-----------------QENLAAVVS-CSSWASSAIHPLAAEKDIFHVAIGSAALKRTE---PGHTIRLTVGVQQEQE  117 (568)
T ss_dssp             HH-----------------CTTEEEEEE-ESHHHHHHHHHHHHHTTCEEEEESCTTCCCCS---TTCCEECSCCHHHHHH
T ss_pred             hc-----------------CCCcEEEEe-CCcHHHHhHHHHHHhCCCEEEEecCCCccccC---CCCeEEccCChHHHHH
Confidence            21                 025666665 56666667778888999999998776554432   3778999998888888


Q NP_000836.2     205 AMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANE  284 (908)
Q Consensus       205 ~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~~~  284 (908)
                      ++++++.  +|+++++++.++.++....+.+++.++..    +.....+.  .+..++...+++++. .++|+|++.+ .
T Consensus       118 ~~~~~~~--~~~~v~i~~~~~~~~~~~~~~~~~~~~~~----~~~~~~~~--~~~~~~~~~~~~~~~-~~~~~v~~~~-~  187 (568)
T 5ERE_A          118 QLAAYLT--DFERIAVLAMDNNLGSSWIRMLEDRFPKQ----VVAAQEYN--PQQMDIAAQLATIKA-RDSEALVLIS-A  187 (568)
T ss_dssp             HHHHHHT--TCSSEEEEEESSHHHHHHHHHHHHHCTTT----EEEEEEEC--TTTCCCHHHHHHHHT-TTCSEEEEEC-S
T ss_pred             HHHHHHc--CCCEEEEEEecChhHHHHHHHHHHHcCCc----eeEEeeeC--ccCCCHHHHHHHHHh-CCCCEEEEEc-h
Confidence            8888886  89999999977777777777776665431    11112222  123356666777763 5788887776 4


Q NP_000836.2     285 DDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAEFWE  364 (908)
Q Consensus       285 ~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  364 (908)
                      ..+..+++++++.|+.  +.|++.+.+......  .......+.+...+                 . .+....|.+.++
T Consensus       188 ~~~~~~l~~~~~~g~~--~~~~~~~~~~~~~~~--~~~~~~~g~~~~~~-----------------~-~~~~~~~~~~~~  245 (568)
T 5ERE_A          188 GEAATIAKQARQAGIK--AQLVGTRPIQRAEVL--AASAFTNGLVYTYP-----------------S-YNQDHPFMSAFT  245 (568)
T ss_dssp             TTHHHHHHHHHHTTCC--CEEEECGGGCCHHHH--HTHHHHTTCEEEEE-----------------C-CCTTSHHHHHHH
T ss_pred             HHHHHHHHHHHHCCCC--CEEEeCChhcCHHHH--HhhhhcCeeEEEcC-----------------C-CcCCcHHHHHHH
Confidence            5677888888888773  456665433221110  00111122111100                 0 001111222222


Q NP_000836.2     365 ENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKELLG  444 (908)
Q Consensus       365 ~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~l~~  444 (908)
                      +.++                           ..++.++..+|||++++++|+++...                +++.+.+
T Consensus       246 ~~~~---------------------------~~~~~~~~~~yda~~~~~~al~~~~~----------------~~~~~~~  282 (568)
T 5ERE_A          246 DRYG---------------------------LEPGFFGVEAYDLCTTLSRALEQGRQ----------------TPKALFE  282 (568)
T ss_dssp             HHHS---------------------------SCCCHHHHHHHHHHHHHHHHHHTTCC----------------SHHHHHH
T ss_pred             HHHC---------------------------CCCChHHHHHHHHHHHHHHHHHhcCC----------------CHHHHHH
Confidence            2221                           11235678899999999999987531                3446777


Q NP_000836.2     445 YIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTNQ  494 (908)
Q Consensus       445 ~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~~  494 (908)
                      +|++..|.|.+| ++.|+++|++...+.+.+++    ++.++.++.|...
T Consensus       283 ~l~~~~~~g~~g-~~~~~~~g~~~~~~~i~~~~----~~~~~~~~~~~~~  327 (568)
T 5ERE_A          283 WYAGNTFTGALG-KVTFANDGDASYPYIFKKVT----ESGFRVAEFQFPM  327 (568)
T ss_dssp             HHTTCEEEETTE-EEEECTTSBEECCEEEEEEE----TTEEEECTTHHHH
T ss_pred             HHhcCCcccccE-EEEECCCCCccccEEEEEEE----CCeEEEEEEEcch
Confidence            888888999988 89999888887778888887    3578889988764


No 129
>3CKM_A Uncharacterized protein HI1655; YraM, periplasmic-binding protein, lipoprotein, unliganded; 1.35A {Haemophilus influenzae} SCOP: c.93.1.1
Probab=99.17  E-value=3.7e-15  Score=155.57  Aligned_cols=322  Identities=12%  Similarity=0.097  Sum_probs=193.4  Template_Neff=11.900

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ++++||+++|.++...          ..+.....|++.|++          |+++++.+.|+.++  .    ..+.++++
T Consensus         1 ~~i~ig~~~p~~~~~~----------~~~~~~~~g~~~a~~----------g~~i~~~~~d~~~~--~----~~~~~~~l   54 (327)
T 3CKM_A            1 MVSQIGLLLPLSGDGQ----------ILGTTIQSGFNDAKG----------NSTIPVQVFDTSMN--S----VQDIIAQA   54 (327)
T ss_pred             CCeEEEEEecCCCCCh----------hHhHHHHHHHHHHHc----------CeeEEEEEEcCCcH--H----HHHHHHHH
Confidence            3689999999876421          245677788888875          34577777776553  1    22333333


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANI-LRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~-~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ..                   ++++++||+.++.....+... +...++|+|.+.+..+.    ...++.+++.+++...
T Consensus        55 ~~-------------------~~v~~iig~~~~~~~~~~~~~~~~~~~ip~i~~~~~~~~----~~~~~~~~~~~~~~~~  111 (327)
T 3CKM_A           55 KQ-------------------AGIKTLVGPLLKQNLDVILADPAQIQGMDVLALNATPNS----RAIPQLCYYGLSPEDE  111 (327)
T ss_pred             HH-------------------cCCCEEEcCCCcHHHHhHHHHHHHHhCCCEEeCCCCCcc----cCCCCEEEecCCHHHH
Confidence            32                   478899998777666666665 78889999988765432    1246678888888888


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFA  282 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~  282 (908)
                      ++.+++++.+.+|+++++++.++.++....+.+++.+++. ++++.....+.  . ..++...++++.  .++|+|++..
T Consensus       112 ~~~~~~~l~~~~~~~v~vv~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~-~~~~~~~~~~~~--~~~~~v~~~~  185 (327)
T 3CKM_A          112 AESAANKMWNDGVRNPLVAMPQNDLGQRVGNAFNVRWQQL-AGTDANIRYYN--L-PADVTYFVQENN--SNTTALYAVA  185 (327)
T ss_pred             HHHHHHHHHHcCCCEEEEEEcCCHHHHHHHHHHHHHHHHc-CCeEeEEeecC--C-CCCcHHHHHHHh--cCCCEEEEeC
Confidence            8888998877899999999977778888888888888775 35554332222  1 124445555553  4789888777


Q NP_000836.2     283 NEDDIRRILEAAKKLNQSGHFLWIGSDSWGSKIAP-VYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFAE  361 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~~~~~~i~~~~~~~~~~~-~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  361 (908)
                      ....+..+++++++.+.  +..+++.+.|...... .........+.+....         .+..    .  ...+...+
T Consensus       186 ~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~---------~~~~----~--~~~~~~~~  248 (327)
T 3CKM_A          186 SPTELAEMKGYLTNIVP--NLAIYASSRASASATNTNTDFIAQMNGVQFSDI---------PFFK----D--TNSPQYQK  248 (327)
T ss_pred             CHHHHHHHHHHHHHcCC--CCCEEeccCcCChhhhcHHhhhhhhccEEEEec---------CCCC----C--CCCHHHHH
Confidence            65556777777776544  3456655433321110 0000111222221110         0000    0  00011111


Q NP_000836.2     362 FWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMHKDLCPGYIGLCPRMSTIDGKE  441 (908)
Q Consensus       362 ~~~~~~~~~~~~~~~~~~~~~~c~~~~~~~~~~~~~~~~~~~~~yDAv~~la~Al~~~~~~~~~~~~~~~~~~~~~~~~~  441 (908)
                       +.+.+...                         ..++.++..+||+++++++. +.                       
T Consensus       249 -f~~~~~~~-------------------------~~~~~~~~~~yda~~~~~~~-~~-----------------------  278 (327)
T 3CKM_A          249 -LAKSTGGE-------------------------YQLMRLYAMGADAWLLINQF-NE-----------------------  278 (327)
T ss_pred             -HHHHhCCC-------------------------CCCCHHHHHHHHHHHHHHHH-HH-----------------------
Confidence             11111110                         01234577899999998872 11                       


Q NP_000836.2     442 LLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITNKSTEYKVIGHWTN  493 (908)
Q Consensus       442 l~~~l~~~~f~G~~G~~v~Fd~~G~~~~~~~i~~~~~~~~~~~~~~Vg~~~~  493 (908)
                       .+.+++..|.|.+| ++.|+++|++...+.+.+++    ++.+..++.|..
T Consensus       279 -l~~~~~~~~~g~~g-~~~f~~~g~~~~~~~v~~~~----~g~~~~~~~~~~  324 (327)
T 3CKM_A          279 -LRQVPGYRLSGLTG-ILSADTNCNVERDMTWYQYQ----DGAIVPVVDHHH  324 (327)
T ss_pred             -HHHhcCCcccccce-eEEeCCCCCccCCEEEEEEE----CCEEEECCCccc
Confidence             12233456888888 89999888776677777776    356777777654


No 130
>5VBG_A Penicillin-binding protein activator LpoA; Gram-negative bacteria, Outer membrane lipoprotein; HET: MSE; 2.8A {Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)}
Probab=98.94  E-value=1.6e-13  Score=154.27  Aligned_cols=215  Identities=12%  Similarity=0.095  Sum_probs=144.9  Template_Neff=11.300

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.++...          ..+.....|++.|++          |.++++.+.|+.++.      ....
T Consensus       219 ~~~~~~i~Ig~~~p~sg~~~----------~~~~~~~~g~~~a~~----------g~~i~~~~~d~~~~~------~~~~  272 (543)
T 5VBG_A          219 FQQTNVSQIGLLLPLSGDGQ----------ILGTTIQSGFNDAKG----------NSTIPVQVFDTSMNS------VQDI  272 (543)
T ss_dssp             CCCCCCCCEEEEECCSSTTH----------HHHHHHHHHHHHHHT----------TCCCCEEEEETTTSC------HHHH
T ss_pred             hccCCCcEEEEEecCCCCch----------HHHHHHHHHHHHHcc----------CCCCCEEEEeCCCCC------HHHH
Confidence            45678899999999987531          345677788888873          345777777876542      1222


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVAN-ILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~-~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      ++++..                   +++++|||+.++.....++. ++...+||+|++.+..+.    ..+++.+++.++
T Consensus       273 ~~~l~~-------------------~~v~~iig~~~s~~~~~~~~~~~~~~~ip~i~~~~~~~~----~~~~~~~~~~~~  329 (543)
T 5VBG_A          273 IAQAKQ-------------------AGIKTLVGPLLKQNLDVILADPAQIQGMDVLALNATPNS----RAIPQLCYYGLS  329 (543)
T ss_dssp             HHHHHH-------------------TTCCEEECCCSHHHHHHHHHCGGGGTTCEEEESCCCTTC----CCCTTEEECCCC
T ss_pred             HHHHHH-------------------CCCCEEECCCCHHHHHHHHcCchhhcCCeEEEecCCCCc----ccCCCceEeeCC
Confidence            233222                   57899999877766655544 467899999988765543    124677888888


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ....+..+++++.+.+|++|++++.++.++....+.+++.+++. ++++.....+.  . ..++...++++.  .++|+|
T Consensus       330 ~~~~~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~-~~d~~~~~~~~~--~~~d~i  403 (543)
T 5VBG_A          330 PEDEAESAANKMWNDGVRNPLVAMPQNDLGQRVGNAFNVRWQQL-AGTDANIRYYN--L-PADVTYFVQENN--SNTTAL  403 (543)
T ss_dssp             HHHHHHHHHHHHHHTTCCEEEEEEESSHHHHHHHHHHHHHHHHH-HSSCCEEEEES--S-TTHHHHHHHHHC--CTTEEE
T ss_pred             hHHHHHHHHHHHHHcCCCCcEEEcCCCHHHHHHHHHHHHHHHHh-hCCcCeeEEeC--C-ccchhHhhhccc--CCCCEE
Confidence            88888888998887899999999977778877888888877765 45554332222  1 234445555553  378888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGSDSW  311 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~  311 (908)
                      ++.+.+..+..+++++++.+.  ++.|++.+.|
T Consensus       404 ~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~  434 (543)
T 5VBG_A          404 YAVASPTELAEMKGYLTNIVP--NLAIYASSRA  434 (543)
T ss_dssp             EECCCHHHHHHHHHHTTTTCT--TCEEEECGGG
T ss_pred             EEecCHHHHHHHHHHHhhccC--CCcEEEcchh
Confidence            777666667777777776443  3456655433


No 131
>5KCN_A Penicillin-binding protein activator LpoA; Outer membrane lipoprotein, PBP1A, transpeptidase.; 1.965A {Haemophilus influenzae}
Probab=98.94  E-value=1.6e-13  Score=154.22  Aligned_cols=215  Identities=12%  Similarity=0.095  Sum_probs=144.4  Template_Neff=11.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++++||+++|.++...          ..+.....|++.|++          |.++++.+.|+.++.      ....
T Consensus       219 ~~~~~~i~Ig~~~p~sg~~~----------~~~~~~~~g~~~a~~----------g~~i~~~~~d~~~~~------~~~~  272 (543)
T 5KCN_A          219 FQQTNVSQIGLLLPLSGDGQ----------ILGTTIQSGFNDAKG----------NSTIPVQVFDTSMNS------VQDI  272 (543)
T ss_pred             ccCCCCeEEEEEEeCCCCCh----------HHHHHHHHHHHHHHC----------CeeEEEEEEcCCCCH------HHHH
Confidence            45678899999999986531          345677888888873          345777777776542      1222


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVAN-ILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~-~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      ++++..                   ++++++||+.++.....++. ++...+||+|++.+..+.    ...++.+++.++
T Consensus       273 ~~~l~~-------------------~~v~~iig~~~s~~~~~~~~~~~~~~~ip~i~~~~~~~~----~~~~~~~~~~~~  329 (543)
T 5KCN_A          273 IAQAKQ-------------------AGIKTLVGPLLKQNLDVILADPAQIQGMDVLALNATPNS----RAIPQLCYYGLS  329 (543)
T ss_pred             HHHHHh-------------------CCCCEEECCCChHHHHHHHHHHHHHhCCCEEeCCCCCcc----cCCCCeeEecCC
Confidence            233222                   57899999887766655544 468899999988765542    124677888888


Q NP_000836.2     199 DSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ....+..+++++.+.+|+++++++.++.++....+.+++.+++. ++++.....+.  . ..++...++++.  .++|+|
T Consensus       330 ~~~~~~~~~~~~~~~~~~~v~il~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~--~-~~~~~~~~~~~~--~~~d~i  403 (543)
T 5KCN_A          330 PEDEAESAANKMWNDGVRNPLVAMPQNDLGQRVGNAFNVRWQQL-AGTDANIRYYN--L-PADVTYFVQENN--SNTTAL  403 (543)
T ss_pred             HHHHHHHHHHHHHHcCCCEEEEEeCCCHHHHHHHHHHHHHHHHc-CCeEeEEEeCC--C-CCCcHHHHHHhh--cCCCEE
Confidence            88888888988888899999999977778887888888877765 45554332232  1 224444555553  378888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGSDSW  311 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~~~  311 (908)
                      ++.+.+.....+++++++.+.  ++.|++.+.|
T Consensus       404 ~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~  434 (543)
T 5KCN_A          404 YAVASPTELAEMKGYLTNIVP--NLAIYASSRA  434 (543)
T ss_pred             EEcCCHHHHHHHHHHHHHhCC--CCCEEecccc
Confidence            777666566777777775443  3455655433


No 132
>4PYR_A Putative branched-chain amino acid ABC; Structural Genomics, PSI-Biology, Midwest Center; HET: GSH; 1.45A {Chromobacterium violaceum}
Probab=98.94  E-value=1.7e-13  Score=141.16  Aligned_cols=204  Identities=12%  Similarity=0.096  Sum_probs=132.6  Template_Neff=11.700

Q NP_000836.2      45 DIILGGLFPVH-AKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        45 ~i~Ig~l~p~~-~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      +++||++.|.+ +...          ..+....+|+++|+++ |        .++++.+.|+++  ..    ..+.++++
T Consensus         1 ~i~ig~~~~~s~g~~~----------~~~~~~~~g~~~a~~~-n--------~~i~l~~~d~~~--~~----~~~~~~~l   55 (305)
T 4PYR_A            1 KVRIGVILPAESSALG----------EAAAVVRSGVEAAAQV-D--------QSAELYSVDATG--DN----VVERYRAA   55 (305)
T ss_dssp             CEEEEEEECCTTSTTH----------HHHHHHHHHHHHHHHH-H--------CCEEEEEEECCG--GG----HHHHHHHH
T ss_pred             CeeEEEEecCCCccch----------HHHHHHHHHHHHHHhc-C--------CCCeEEEEeCCC--cc----HHHHHHHH
Confidence            47899999988 6431          3567788999999998 6        246677777654  21    22233333


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      +.                   ++++++||+.++.....++.   ..++|+|.+.+..+. .  ...++.+++.++...++
T Consensus        56 ~~-------------------~~v~~iig~~~s~~~~~~~~---~~~ip~i~~~~~~~~-~--~~~~~~~~~~~~~~~~~  110 (305)
T 4PYR_A           56 VA-------------------DGVNVVIGPLSRDSIVKLAP---SVTVPTLALNSVGRE-A--AANPKLYSLSLIVEGEA  110 (305)
T ss_dssp             HH-------------------TTCCEEECCCSHHHHHHHGG---GCCSCEEESSCCCTT-S--CCCTTEEECCCCHHHHH
T ss_pred             HH-------------------CCCCEEECCCCHHHHHHHhh---cCCCCEEEecCCChh-h--ccCCCeEEEecChHHHH
Confidence            32                   47889999877665544433   689999987765443 1  13567788888888888


Q NP_000836.2     204 QAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFAN  283 (908)
Q Consensus       204 ~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~~  283 (908)
                      ..+++++.+.+|+++++++.+++++....+.+++.+++. ++++.....+..    .++...+.  + ..++|+|++...
T Consensus       111 ~~~~~~~~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-g~~v~~~~~~~~----~d~~~~~~--~-~~~~d~v~~~~~  182 (305)
T 4PYR_A          111 RQLARLMRDDSRAAPLLVVGGDALSQRLGKAFADEWRAA-AGKPVRQMAFDA----NDMAPLLQ--A-AGQADAVALALD  182 (305)
T ss_dssp             HHHHHHHHHTTCSSEEEEECSSHHHHHHHHHHHHHHHHH-HSSCCEEEECCT----TCCHHHHH--H-HHTCSEEEEESC
T ss_pred             HHHHHHHHHCCCCceEEEEcCCHHHHHHHHHHHHHHHHC-CCcccEEEEeCh----hhhHHHHH--h-hcCCCEEEEeCC
Confidence            899999887899999999977778888888888877765 455543322221    13333332  2 247898877765


Q NP_000836.2     284 EDDIRRILEAAKKLNQSGHFLWIGSDSW  311 (908)
Q Consensus       284 ~~~~~~~l~~~~~~g~~~~~~~i~~~~~  311 (908)
                      .... .++.++.+.    +..|++.+.|
T Consensus       183 ~~~~-~~l~~~~~~----~~~~~~~~~~  205 (305)
T 4PYR_A          183 VAQA-ARLKSALTP----DVPVYGTSQL  205 (305)
T ss_dssp             HHHH-HHHHHHSCT----TSCEEECGGG
T ss_pred             HHHH-HHHHHHcCC----CCCEEeeccc
Confidence            4444 555554431    2456665433


No 133
>4YLE_A Simple sugar transport system substrate-binding; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: MSE; 1.7A {Burkholderia multivorans}
Probab=97.77  E-value=1.5e-08  Score=103.45  Aligned_cols=224  Identities=12%  Similarity=0.071  Sum_probs=130.6  Template_Neff=12.200

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+.++||++.|..+.            ..+.....+++.++++.|.      ++++.+...|+..++    +...+.
T Consensus        27 ~~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~a~~~~~~------~~~~~~~~~d~~~~~----~~~~~~   84 (316)
T 4YLE_A           27 AQAAGKPKVALVMKSLAN------------EFFLTMENGAKEYQKHNAS------QFDLITNGIKDETDT----ANQIRI   84 (316)
T ss_dssp             ---CCCCEEEEEEEETTS------------HHHHHHHHHHHHHHHHTTT------TCEEEEEEESSTTCH----HHHHHH
T ss_pred             hhhcCCCEEEEEecCCCC------------hHHHHHHHHHHHHHHhcCC------ccEEEEcccCCCCCH----HHHHHH
Confidence            355678999999997542            2556778888888888653      233443333433332    222333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      ++++..                   ++++++|+...+.... .....+...++|+|..+...+........++++++.++
T Consensus        85 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~~~~~~~~~~v~~~  145 (316)
T 4YLE_A           85 VEQMIV-------------------SKVDAIVLAPADSKALVPVVKKAVDAGIIVVNIDNRLDPDVLKSKNLNVPFVGPD  145 (316)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCEEEEESSCCCHHHHHTTTCCCCEEEEC
T ss_pred             HHHHHh-------------------cCCCEEEEcCCCccchHHHHHHHHHCCCEEEEEeCCCChHHHhhcCCCCcEeccC
Confidence            444332                   4788888754443322 44456677899999887654321111113567788888


Q NP_000836.2     199 DSYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TP  273 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~  273 (908)
                      +...++.+++++.+.  +.+++++++.  ++.++..+.+++++.+++. ++.+.......  .+..+....++++++ ..
T Consensus       146 ~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~  222 (316)
T 4YLE_A          146 NRKGARKVGDYLAKKLKAGDQVGIVEGVSTTTNAQQRTAGFQDAMKAG-GMKVVSVQSGE--WEIDKGNAVASAMLNEYP  222 (316)
T ss_dssp             HHHHHHHHHHHHHHHSCTTCEEEEEESCTTSHHHHHHHHHHHHHHHHH-TCEEEEEEECT--TCHHHHHHHHHHHHHHCT
T ss_pred             hHHHHHHHHHHHHHHccCCCeEEEEEcCCCChhHHHHHHHHHHHHHhC-CCeEEEEeecC--CCHHHHHHHHHHHHHHCC
Confidence            888888888887654  4678999885  4456677788888888775 35443221111  112233444555542 13


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++++|++.. +..+..+++++++.|+..++.+++.
T Consensus       223 ~~~~i~~~~-~~~~~~~~~~l~~~g~~~~~~i~~~  256 (316)
T 4YLE_A          223 NLKALLCGN-DNMAIGAVSAVRAAGKQGKVYVVGY  256 (316)
T ss_dssp             TCCEEEESS-HHHHHHHHHHHHHTTCTTTSEEECS
T ss_pred             CeeEEEECC-hHHHHHHHHHHHHcCCCCCeEEEEe
Confidence            566776654 4456677888888776333444444


No 134
>4RK1_B Ribose transcriptional regulator; sugar binding, transcription regulation, Enzyme; HET: CL, MSE, RIB; 1.9A {Enterococcus faecium DO}
Probab=97.68  E-value=2.9e-08  Score=99.18  Aligned_cols=204  Identities=13%  Similarity=0.094  Sum_probs=120.4  Template_Neff=12.200

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++.....+++.++++.+          +++.+.|+..++.    ...+.++
T Consensus         4 ~~~~~~I~~~~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~   57 (280)
T 4RK1_B            4 TKETKTIGVLVPDITN------------PFFSTLMRGIEDILYKQN----------FVTILCNADSDHQ----KEIEYLA   57 (280)
T ss_dssp             ----CEEEEEESCTTS------------HHHHHHHHHHHHHHGGGT----------CEEEEEECCC---------CCHHH
T ss_pred             ccCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHCC----------CEEEEEeCCCCHH----HHHHHHH
Confidence            4567899999987542            245667788888877642          3344455443322    2233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++..                   ++++++|+...+.........+...++|+|..+...+       .++.+++.+++..
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~~~~~  111 (280)
T 4RK1_B           58 ELTR-------------------RGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKS-------EGFSDAVRTDDFR  111 (280)
T ss_dssp             HHHH-------------------TTCCEEEECCTTSCHHHCCCCCCTTTCCEEEETTSCC-------CTTCEEEEECHHH
T ss_pred             HHHH-------------------cCCCEEEEeCCCCChHHHHHHHHHcCCCEEEECCCCC-------CCCCceEEECcHH
Confidence            3332                   4788888755443333445566778999988765432       1356677777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      .++.+++++.+.+++++++++.  +..++..+.++|++.+++. ++.+..........+..+....++++++ .++|+|+
T Consensus       112 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~d~i~  189 (280)
T 4RK1_B          112 GGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVY-QIPHDQLILLPTQFSKQGGYQITAELLD-SAATGVF  189 (280)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEEESSCCHHHHHHHHHHHHHHHHT-TCCGGGEEEEEECSSHHHHHHTHHHHHH-SCCCEEE
T ss_pred             HHHHHHHHHHHCCCCEEEEEcCCCCChHHHHHHHHHHHHHHHc-CCCccceEEeCCCcccccHHHHHHHHhh-CCCCEEE
Confidence            7888888887678889999985  3345666778888887764 3333211111100112234455566653 4788887


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +.. +..+..+++++++.|+.
T Consensus       190 ~~~-~~~~~~~~~~l~~~g~~  209 (280)
T 4RK1_B          190 ALN-DELAFGLYRGLEEAGKS  209 (280)
T ss_dssp             ESS-HHHHHHHHHHHHHTTCC
T ss_pred             ECC-hHHHHHHHHHHHHcCCC
Confidence            765 33467788888887764


No 135
>4RK1_D Ribose transcriptional regulator; sugar binding, transcription regulation, Enzyme; HET: RIB, CL; 1.9A {Enterococcus faecium DO}
Probab=97.68  E-value=2.9e-08  Score=99.18  Aligned_cols=204  Identities=13%  Similarity=0.094  Sum_probs=120.7  Template_Neff=12.200

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++.....+++.++++.+          +++.+.|+..++.    ...+.++
T Consensus         4 ~~~~~~I~~~~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~   57 (280)
T 4RK1_D            4 TKETKTIGVLVPDITN------------PFFSTLMRGIEDILYKQN----------FVTILCNADSDHQ----KEIEYLA   57 (280)
T ss_dssp             ----CEEEEEESCTTS------------HHHHHHHHHHHHHHHTTT----------CEEEEEECCC--------CCCHHH
T ss_pred             ccCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHCC----------CEEEEEeCCCCHH----HHHHHHH
Confidence            4567899999987542            245667788888877642          3344455443322    2233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++..                   ++++++|+...+.........+...++|+|..+...+       .++.+++.+++..
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~~~~~  111 (280)
T 4RK1_D           58 ELTR-------------------RGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKS-------EGFSDAVRTDDFR  111 (280)
T ss_dssp             HHHH-------------------TTCCEEEECCTTSCHHHCCCCCCTTTCCEEEETTSCC-------CTTCEEEEECHHH
T ss_pred             HHHH-------------------cCCCEEEEeCCCCChHHHHHHHHHcCCCEEEECCCCC-------CCCCceEEECcHH
Confidence            3332                   4788888755443333445566778999988765432       1356677777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      .++.+++++.+.+++++++++.  +..++..+.++|++.+++. ++.+..........+..+....++++++ .++|+|+
T Consensus       112 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~d~i~  189 (280)
T 4RK1_D          112 GGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVY-QIPHDQLILLPTQFSKQGGYQITAELLD-SAATGVF  189 (280)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEEESSCCHHHHHHHHHHHHHHHHT-TCCGGGEEEEEECSSHHHHHHTHHHHHT-SCCSEEE
T ss_pred             HHHHHHHHHHHCCCCEEEEEcCCCCChHHHHHHHHHHHHHHHc-CCCccceEEeCCCcccccHHHHHHHHhh-CCCCEEE
Confidence            7888888887678889999985  3345666778888887764 3333211111100112234455566653 4788887


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +.. +..+..+++++++.|+.
T Consensus       190 ~~~-~~~~~~~~~~l~~~g~~  209 (280)
T 4RK1_D          190 ALN-DELAFGLYRGLEEAGKS  209 (280)
T ss_dssp             ESS-HHHHHHHHHHHHHTTCC
T ss_pred             ECC-hHHHHHHHHHHHHcCCC
Confidence            765 33467788888887764


No 136
>3BRQ_A HTH-type transcriptional regulator ascG; transcriptional repressor structure Escherichia coli; HET: MSE, SO4, FRU; 2.0A {Escherichia coli}
Probab=97.64  E-value=3.8e-08  Score=99.33  Aligned_cols=208  Identities=10%  Similarity=0.021  Sum_probs=121.6  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||++.|..+..          ..++.....+++.++++.+          +++.+.|+..++.    ...+.+
T Consensus        15 ~~~~~~~I~~i~~~~~~~----------~~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~   70 (296)
T 3BRQ_A           15 SAKSTQTLGLVVTNTLYH----------GIYFSELLFHAARMAEEKG----------RQLLLADGKHSAE----EERQAI   70 (296)
T ss_dssp             ----CCEEEEEECGGGCC------------CHHHHHHHHHHHHHHTT----------CEEEEECCTTSHH----HHHHHH
T ss_pred             ccCCCCEEEEEecCcccC----------CccHHHHHHHHHHHHHHcC----------CeEEEEeCCCCHH----HHHHHH
Confidence            345689999999976421          1245567778877777642          3444555544422    233344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   .+++++|+...+.....+...++..++|+|..+...+.       +.++++..++.
T Consensus        71 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-------~~~~~v~~~~~  124 (296)
T 3BRQ_A           71 QYLLD-------------------LRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRK-------NSSHSVWCDHK  124 (296)
T ss_dssp             HHHHH-------------------TTCSEEEEECSSSCHHHHHHHHHTCSSCEEEESCCCSS-------SGGGEECCCHH
T ss_pred             HHHHh-------------------cCCCEEEEeCCCCChhhHHHHHHHcCCCEEEeCCCCCC-------CCCcEEEeCcH
Confidence            44332                   47888887655443334445566789999987764331       34566667777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ..++.+++++.+.++++++++..+..  ++..+.++|++.+++. ++.+.....+..+.+..+....++++++. .++|+
T Consensus       125 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  203 (296)
T 3BRQ_A          125 QTSFNAVAELINAGHQEIAFLTGSMDSPTSIERLAGYKDALAQH-GIALNEKLIANGKWTPASGAEGVEMLLERGAKFSA  203 (296)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEECCCTTCHHHHHHHHHHHHHHHTT-TCCCCGGGEECCCSSHHHHHHHHHHHHTC--CCSE
T ss_pred             HHHHHHHHHHHHCCCCeEEEEeCCCCChhHHHHHHHHHHHHHHC-CCCCCccceecCCCChhhHHHHHHHHHHcCCCCCE
Confidence            77777788876668899999985433  5666778888888775 34433221111101122344455555431 23777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       204 v~~~~-~~~~~~~~~~~~~~g~~  225 (296)
T 3BRQ_A          204 LVASN-DDMAIGAMKALHERGVA  225 (296)
T ss_dssp             EEESS-HHHHHHHHHHHHHHTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            77664 44566778888887764


No 137
>3BRQ_B HTH-type transcriptional regulator ascG; transcriptional repressor structure Escherichia coli; HET: SO4, FRU; 2.0A {Escherichia coli}
Probab=97.64  E-value=3.8e-08  Score=99.33  Aligned_cols=208  Identities=10%  Similarity=0.021  Sum_probs=122.3  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||++.|..+..          ..++.....+++.++++.+          +++.+.|+..++.    ...+.+
T Consensus        15 ~~~~~~~I~~i~~~~~~~----------~~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~   70 (296)
T 3BRQ_B           15 SAKSTQTLGLVVTNTLYH----------GIYFSELLFHAARMAEEKG----------RQLLLADGKHSAE----EERQAI   70 (296)
T ss_dssp             ----CCEEEEEEECCSCC----------SSCHHHHHHHHHHHHHHTT----------CEEEEEEEETSHH----HHHHHH
T ss_pred             ccCCCCEEEEEecCcccC----------CccHHHHHHHHHHHHHHcC----------CeEEEEeCCCCHH----HHHHHH
Confidence            345689999999976421          1245567778877777642          3444555544422    233344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   .+++++|+...+.....+...++..++|+|..+...+.       +.++++..++.
T Consensus        71 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-------~~~~~v~~~~~  124 (296)
T 3BRQ_B           71 QYLLD-------------------LRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRK-------NSSHSVWCDHK  124 (296)
T ss_dssp             HHHHH-------------------TTCSEEEEECSSSCHHHHHHHHHTCSSCEEEESSCCSS-------CGGGEECBCHH
T ss_pred             HHHHh-------------------cCCCEEEEeCCCCChhhHHHHHHHcCCCEEEeCCCCCC-------CCCcEEEeCcH
Confidence            44332                   47888887655443334445566789999987764331       34566667777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ..++.+++++.+.++++++++..+..  ++..+.++|++.+++. ++.+.....+..+.+..+....++++++. .++|+
T Consensus       125 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  203 (296)
T 3BRQ_B          125 QTSFNAVAELINAGHQEIAFLTGSMDSPTSIERLAGYKDALAQH-GIALNEKLIANGKWTPASGAEGVEMLLERGAKFSA  203 (296)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEECCCTTCHHHHHHHHHHHHHHHHT-TCCCCGGGEECCCSSHHHHHHHHHHHHHHCCCCSE
T ss_pred             HHHHHHHHHHHHCCCCeEEEEeCCCCChhHHHHHHHHHHHHHHC-CCCCCccceecCCCChhhHHHHHHHHHHcCCCCCE
Confidence            77777788876668899999985433  5666778888888775 34433221111101122344455555431 23777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       204 v~~~~-~~~~~~~~~~~~~~g~~  225 (296)
T 3BRQ_B          204 LVASN-DDMAIGAMKALHERGVA  225 (296)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            77664 44566778888887764


No 138
>5DTE_B Monosaccharide-transporting ATPase (E.C.3.6.3.17); Solute Binding Protein, ENZYME FUNCTION; HET: ALL; 2.7A {Actinobacillus succinogenes (strain ATCC 55618 / 130Z)}
Probab=97.59  E-value=5.2e-08  Score=99.26  Aligned_cols=222  Identities=16%  Similarity=0.113  Sum_probs=126.5  Template_Neff=11.700

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||++.|..+.            .++.....+++.++++.        |+++.+...|+..++    +...+.+
T Consensus        22 ~~~~~~~Igvv~~~~~~------------~~~~~~~~g~~~a~~~~--------g~~v~~~~~~~~~~~----~~~~~~~   77 (311)
T 5DTE_B           22 SMADKPQIALLMKTLSN------------EYFISMRQGAEETAKQK--------DIDLIVQVAEKEDST----EQLVGLV   77 (311)
T ss_dssp             ---CCCEEEEEESCSSS------------HHHHHHHHHHHHHHHHT--------TCEECCEECSSTTCH----HHHHHHH
T ss_pred             ccCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHc--------CCEEEEEccCCCCcH----HHHHHHH
Confidence            34468999999997542            25567788888888775        345655555543332    1222333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      ++++.                   ++++++|+...+... ......+.+.++|+|..+...+........++.+.+.+++
T Consensus        78 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~~~~~~~~~~v~~d~  138 (311)
T 5DTE_B           78 ENMIA-------------------KKVDAIIVTPNDSIAFIPAFQKAEKAGIPIIDLDVRLDAKAAEAAGLKFNYVGVDN  138 (311)
T ss_dssp             HHHHH-------------------TTCSEEEECCSCTTTTHHHHHHHHHTTCCEEEESSCCCHHHHHHTTCCCEEEECCH
T ss_pred             HHHHh-------------------CCCCEEEECCCCccchHHHHHHHHHCCCCEEEEcCCCCHHHHHHhcCceEEEEeCh
Confidence            43332                   467877764433322 2444566778999998876543211100124567777888


Q NP_000836.2     200 SYQAQAMVDIVTAL-GW-NYVSTLASE--GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPN  274 (908)
Q Consensus       200 ~~~~~~~~~~l~~~-~~-~~v~ii~~~--~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~  274 (908)
                      ...++.+++++.+. +. ++++++...  ..++..+.++|++.+++.+++++.......  .+..+....++++++ ..+
T Consensus       139 ~~~~~~~~~~l~~~~g~~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~  216 (311)
T 5DTE_B          139 FNGGYLEAKNLAEAIGKKGNVAILEGIPGVDNGEQRKGGALKAFAEYPDIKIVASQSAN--WETEQALNVTTNILTANPN  216 (311)
T ss_dssp             HHHHHHHHHHHHHHTTSEEEEEEEECCSSCHHHHHHHHHHHHHHTTCTEEEEEEEEECT--TCHHHHHHHHHHHTTTSTT
T ss_pred             HHHHHHHHHHHHHHhCCCeEEEEEECCCCChhHHHHHHHHHHHHHhCCCeEEEEeccCC--CCHHHHHHHHHHHHHHCCC
Confidence            77888888887654 76 889999743  235667788888887764223332211111  112234444555542 135


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|+|++.. +..+..+++++++.|+..++.+++.
T Consensus       217 ~d~i~~~~-~~~a~~~~~~l~~~g~~~~i~vi~~  249 (311)
T 5DTE_B          217 INGIFAAN-DNMAIGAVTAVENAGLAGKVLVSGY  249 (311)
T ss_dssp             CCEEEESS-HHHHHHHHHHHHHTTCBTTBEEECC
T ss_pred             cCEEEECC-hhhHHHHHHHHHHCCCCCCeEEEEe
Confidence            66676553 4456677888887776323344443


No 139
>3KSM_B ABC-type sugar transport system, periplasmic; ABC-type sugar transport system, periplasmic; HET: MSE, BDR; 1.9A {Hahella chejuensis}
Probab=97.58  E-value=5.5e-08  Score=96.87  Aligned_cols=212  Identities=15%  Similarity=0.056  Sum_probs=121.5  Template_Neff=12.200

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIE  125 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~~  125 (908)
                      ++||++.|..+.            .++..+..+++.++++.        |+++.+...|+..++.    ...+.+++++.
T Consensus         1 i~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~~~~~~~~~~~~~~----~~~~~~~~~~~   56 (276)
T 3KSM_B            1 PKLLLVLKGDSN------------AYWRQVYLGAQKAADEA--------GVTLLHRSTKDDGDIA----GQIQILSYHLS   56 (276)
T ss_dssp             -CEEEECSCSSS------------THHHHHHHHHHHHHHHH--------TCCEEECCCSSTTCHH----HHHHHHHHHHH
T ss_pred             CeEEEEcCCCCC------------HHHHHHHHHHHHHHHHh--------CCEEEEecCCCCCCHH----HHHHHHHHHHH
Confidence            478999887542            25567778888888775        3456555545433322    22333333332


Q NP_000836.2     126 KDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       126 ~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                                        .+++|++|+...+.... .....+...++|+|..+...+.      .++++++.+++...++
T Consensus        57 ------------------~~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~d~~~~~~  112 (276)
T 3KSM_B           57 ------------------QAPPDALILAPNSAEDLTPSVAQYRARNIPVLVVDSDLAG------DAHQGLVATDNYAAGQ  112 (276)
T ss_dssp             ------------------CCC-CEEEECCSCTTTTHHHHHHHHHTTCCEEEESSCCSS------SSSSEEEECCHHHHHH
T ss_pred             ------------------hCCCCEEEEcCCCHHhcHHHHHHHHHCCCCEEEEcCCCCC------CccceEEEcCHHHHHH
Confidence                              14788887654443322 3345567789999987654321      2456777777777777


Q NP_000836.2     205 AMVDIVTAL----GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       205 ~~~~~l~~~----~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      .+++++.+.    +.++++++..  ++.++..+.++|++.+++.+ ........+.. .+..+....+++++.. .++++
T Consensus       113 ~~~~~l~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  190 (276)
T 3KSM_B          113 LAARALLATLDLSKERNIALLRLRAGNASTDQREQGFLDVLRKHD-KIRIIAAPYAG-DDRGAARSEMLRLLKETPTIDG  190 (276)
T ss_dssp             HHHHHHHHHSCTTSCEEEEECBCCTTCHHHHHHHHHHHHHHTTCT-TEEEEECCBCC-SCHHHHHHHHHHHHHHCSCCCE
T ss_pred             HHHHHHHHHcCcCCCceEEEEECCCCChhHHHHHHHHHHHHhhcC-CeEEEECCcCC-CCHHHHHHHHHHHHHHCCCCCE
Confidence            888877554    7889999985  34556667788888877643 22111111110 1112333445555421 24677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      |++.. +..+..+++++++.|+..++.+++.
T Consensus       191 i~~~~-~~~~~~~~~~l~~~g~~~~~~i~~~  220 (276)
T 3KSM_B          191 LFTPN-ESTTIGALVAIRQSGMSKQFGFIGF  220 (276)
T ss_dssp             EECCS-HHHHHHHHHHHHHTTCTTSSEEEEE
T ss_pred             EEeCC-hHHHHHHHHHHHHcCCCCceEEEee
Confidence            76654 4456678888888776433444443


No 140
>3KSM_A ABC-type sugar transport system, periplasmic; ABC-type sugar transport system, periplasmic; HET: BDR; 1.9A {Hahella chejuensis}
Probab=97.58  E-value=5.5e-08  Score=96.87  Aligned_cols=212  Identities=15%  Similarity=0.056  Sum_probs=122.8  Template_Neff=12.200

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIE  125 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~~  125 (908)
                      ++||++.|..+.            .++..+..+++.++++.        |+++.+...|+..++.    ...+.+++++.
T Consensus         1 i~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~~~~~~~~~~~~~~----~~~~~~~~~~~   56 (276)
T 3KSM_A            1 PKLLLVLKGDSN------------AYWRQVYLGAQKAADEA--------GVTLLHRSTKDDGDIA----GQIQILSYHLS   56 (276)
T ss_dssp             CEEEEECSCSSS------------THHHHHHHHHHHHHHHH--------TCEEEECCCSSTTCHH----HHHHHHHHHHH
T ss_pred             CeEEEEcCCCCC------------HHHHHHHHHHHHHHHHh--------CCEEEEecCCCCCCHH----HHHHHHHHHHH
Confidence            478999887542            25567778888888775        3456555545433322    22333333332


Q NP_000836.2     126 KDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       126 ~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                                        .+++|++|+...+.... .....+...++|+|..+...+.      .++++++.+++...++
T Consensus        57 ------------------~~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~d~~~~~~  112 (276)
T 3KSM_A           57 ------------------QAPPDALILAPNSAEDLTPSVAQYRARNIPVLVVDSDLAG------DAHQGLVATDNYAAGQ  112 (276)
T ss_dssp             ------------------HSCCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCSS------SCSSEEEECCHHHHHH
T ss_pred             ------------------hCCCCEEEEcCCCHHhcHHHHHHHHHCCCCEEEEcCCCCC------CccceEEEcCHHHHHH
Confidence                              14788887654443322 3345567789999987654321      2456777777777777


Q NP_000836.2     205 AMVDIVTAL----GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       205 ~~~~~l~~~----~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      .+++++.+.    +.++++++..  ++.++..+.++|++.+++.+ ........+.. .+..+....+++++.. .++++
T Consensus       113 ~~~~~l~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  190 (276)
T 3KSM_A          113 LAARALLATLDLSKERNIALLRLRAGNASTDQREQGFLDVLRKHD-KIRIIAAPYAG-DDRGAARSEMLRLLKETPTIDG  190 (276)
T ss_dssp             HHHHHHHHHSCTTSCEEEEECBCCTTCHHHHHHHHHHHHHHTTCT-TEEEEECCBCC-SSHHHHHHHHHHHHHHCSCCCE
T ss_pred             HHHHHHHHHcCcCCCceEEEEECCCCChhHHHHHHHHHHHHhhcC-CeEEEECCcCC-CCHHHHHHHHHHHHHHCCCCCE
Confidence            888877554    7889999985  34556667788888877643 22111111110 1112333445555421 24677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      |++.. +..+..+++++++.|+..++.+++.
T Consensus       191 i~~~~-~~~~~~~~~~l~~~g~~~~~~i~~~  220 (276)
T 3KSM_A          191 LFTPN-ESTTIGALVAIRQSGMSKQFGFIGF  220 (276)
T ss_dssp             EECCS-HHHHHHHHHHHHHTTCTTSSEEEEE
T ss_pred             EEeCC-hHHHHHHHHHHHHcCCCCceEEEee
Confidence            76654 4456678888888776433444443


No 141
>4RSM_A Periplasmic binding protein/LacI transcriptional regulator; SUGAR TRANSPORTER, ABC-TYPE, ENZYME FUNCTION; HET: 3VB; 1.6A {Mycobacterium smegmatis}
Probab=97.58  E-value=5.6e-08  Score=99.91  Aligned_cols=213  Identities=12%  Similarity=0.053  Sum_probs=123.2  Template_Neff=11.300

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...+++++||++.|.++             .++.....+++.++++.|          +++.+.|...+.    ....+.
T Consensus         7 ~~~~~~~~Ig~i~~~~~-------------~~~~~~~~g~~~~~~~~~----------~~l~~~~~~~~~----~~~~~~   59 (327)
T 4RSM_A            7 AANSDTTRIGVTVYDMS-------------SFITAGKEGMDAYAKDNN----------IELIWNSANLDV----STQASQ   59 (327)
T ss_dssp             ----CCEEEEEEESCCC-------------HHHHHHHHHHHHHHHHHT----------EEEEEEECTTCH----HHHHHH
T ss_pred             cccCCCeEEEEEECCcc-------------HHHHHHHHHHHHHHHhCC----------CEEEEecCCCCH----HHHHHH
Confidence            45677899999998753             245667778888887653          344455544332    222333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+.. .......+...++|+|..+...+.      .++.+++.++
T Consensus        60 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d  114 (327)
T 4RSM_A           60 VDSMIN-------------------QGVDAIIVVPVQADSLAPQVASAKAKGIPLVPVNAALDS------KDIAGNVQPD  114 (327)
T ss_dssp             HHHHHH-------------------TTCSEEEEECSCSSCCHHHHHHHHHTTCCEEEBSSCCSC------SCSSCCBEEC
T ss_pred             HHHHHH-------------------cCCCEEEEeCCCccchHHHHHHHHHCCCCEEEECCCCCc------cCCceEEcCC
Confidence            443332                   46787775433322 224445566789999987764331      2456777788


Q NP_000836.2     199 DSYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET--  272 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--  272 (908)
                      +...+..+++++.+.  +.++|+++..  ++.++..+.+++.+.+++.+++.+.......  .+..+....+++++..  
T Consensus       115 ~~~~~~~~~~~l~~~~~~~~~i~~v~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~  192 (327)
T 4RSM_A          115 DVAAGAQEMQMMADRLGGKGNIVILQGPLGQSGELDRSKGIEQVLAKYPDIKVLAKDTAN--WKRDEAVNKMKNWISGFG  192 (327)
T ss_dssp             HHHHHHHHHHHHHHHHTTCEEEEEEECSTTSHHHHHHHHHHHHHHHHCTTEEEEEEEECT--TCHHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHHHHHHHHhCCCcEEEEEECCCCChhHHHHHHHHHHHHHhCCCeEEEEEecCC--CCHHHHHHHHHHHHHhhc
Confidence            777788888887654  6789999985  4445667778888877664223332211111  1112334445555421  


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      .++|+|++.. +..+..+++++++.|.. ++.+++.
T Consensus       193 ~~~d~i~~~~-~~~a~~~~~al~~~g~~-~~~iig~  226 (327)
T 4RSM_A          193 PQIDGVVAQN-DDMGLGALQALKESGRT-GVPIVGI  226 (327)
T ss_dssp             GGCCEEEESS-HHHHHHHHHHHHHTTCC-CCCEECS
T ss_pred             CCCCEEEECC-hHHHHHHHHHHHHcCCC-CCCEEEe
Confidence            3577777664 33566778888877763 2344444


No 142
>6HBD_B ABC transporter periplasmic-binding protein YtfQ; periplasmic binding protein, SUGAR BINDING; HET: GZL, ZN; 2.44A {Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)}
Probab=97.57  E-value=5.7e-08  Score=99.43  Aligned_cols=211  Identities=12%  Similarity=0.056  Sum_probs=122.7  Template_Neff=11.600

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      ....++.++||++.|..+.            .++.....+++.++++.|          +++.+.|+..++.    ...+
T Consensus        11 ~~~~~~~~~Igvi~~~~~~------------~~~~~~~~g~~~a~~~~~----------~~l~~~~~~~~~~----~~~~   64 (320)
T 6HBD_B           11 GSAPDGALTLGFAQVGAES------------GWRTANTESIKSAAEEAG----------VNLKFADANGEQE----KQIS   64 (320)
T ss_dssp             -----CCEEEEEECCCCCS------------HHHHHHHHHHHHHHHHHT----------EEEEEECCTTCHH----HHHH
T ss_pred             CCCCCCCcEEEEEecCCCC------------HHHHHHHHHHHHHHHHcC----------CEEEEECCCCCHH----HHHH
Confidence            4566788999999987542            255667788888887653          3444555543322    2233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASS-VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~-~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   ++++++|....+. ........+...++|+|..+...+...   ..++++++.+
T Consensus        65 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~---~~~~~~~v~~  122 (320)
T 6HBD_B           65 AIRSFIQ-------------------QGVDVIAFSPVVRTGWDAVLQETKNAGIPVILTDRAVDTQD---TDVYKTFIGA  122 (320)
T ss_dssp             HHHHHHH-------------------HTCSEEEECCSSSSSCHHHHHHHHHHTCCEEEESCCCCCSS---SSSCSEEEEC
T ss_pred             HHHHHHH-------------------cCCCEEEEcCCCccCHHHHHHHHHHCCCCEEEeCCCCCCCC---CcchheEecC
Confidence            3443332                   4677766543332 223445566678999998776543211   1355677888


Q NP_000836.2     198 PDSYQAQAMVDIVTA-----LGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL  270 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~-----~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~  270 (908)
                      ++...+..+++++.+     .+.++++++..  +..++..+.++|++.+++.+++.+.......  .+..+....+++++
T Consensus       123 d~~~~~~~~~~~l~~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~  200 (320)
T 6HBD_B          123 DFIEEGRRAGQWVADQYASATGPVNIVQLEGTTGADPAIDRKTGFAEGISKNPNLKIVASQTGD--FTRSGGKQVMEAFL  200 (320)
T ss_dssp             CHHHHHHHHHHHHHHHSSSCSSCEEEEEEECSTTCHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TSHHHHHHHHHHHH
T ss_pred             ChHHHHHHHHHHHHHHHHhcCCCceEEEEEcCCCChHHHHHHHHHHHHHhhCCCeEEEEeecCC--CCHHHHHHHHHHHH
Confidence            877777788877754     47789999985  3456667778888887764224443221111  11223444555554


Q NP_000836.2     271 E-TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       271 ~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      + ..++|+|++.. +..+..+++++++.|+.
T Consensus       201 ~~~~~~d~i~~~~-~~~a~~~~~~l~~~g~~  230 (320)
T 6HBD_B          201 KSTPQIDVVFAQN-DDMGLGAMEAIEAAGKK  230 (320)
T ss_dssp             HHCSCCCEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             HHCCCCCEEEECC-HHHHHHHHHHHHHcCCC
Confidence            2 13567776654 34556788888887764


No 143
>4JOQ_A ABC ribose transporter, periplasmic solute-binding; structural genomics, ribose, ABC transporter; 1.9A {Rhodobacter sphaeroides}
Probab=97.56  E-value=6.4e-08  Score=97.68  Aligned_cols=218  Identities=11%  Similarity=0.018  Sum_probs=129.3  Template_Neff=12.000

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++.....+++.+++++|+.+     ..+++.+.++ .++    ....+.++
T Consensus         4 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~~~~~-----~~~~~~~~~~-~~~----~~~~~~~~   61 (297)
T 4JOQ_A            4 QEKVGTIGIAIPSATH------------GFMGGLNFHAQDTIKRLQEVY-----PQLDFVLATA-GNA----GKMVNDIE   61 (297)
T ss_dssp             CCCCEEEEEEEECCSS------------HHHHHHHHHHHHHHHHHHHHC-----TTEEEEEEEE-SSH----HHHHHHHH
T ss_pred             cccceEEEEEeccCCC------------hhHHHHHHHHHHHHHHHHHHc-----ccccEEEEcC-CCH----HHHHHHHH
Confidence            4578999999997642            256677889999999988643     1344444444 222    12223334


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                  .++++++|+...+.... .....+...++|+|..+...+.     ..++.+++.+++.
T Consensus        62 ~l~~------------------~~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~-----~~~~~~~v~~d~~  118 (297)
T 4JOQ_A           62 DMVA------------------TRNISALVVLPFESEPLTSPVQAVKEAGIWVTVVDRGLSV-----EGIEDLYVAGDNP  118 (297)
T ss_dssp             HHHH------------------HHCCSEEEECCSSTTTTHHHHHHHHHTTCEEEEESSCCSS-----SSCCSEEEEECHH
T ss_pred             HHHH------------------hCCCCEEEEcCCCCCCCcHHHHHHHHcCCEEEEEeCCCCC-----CCceeEEEEcCch
Confidence            3332                  14788888765444322 3445566789999987764431     1345677778887


Q NP_000836.2     201 YQAQAMVDIVTAL--GWNYVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~--~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ..++.+++++.+.  +.++++++..+ ..++..+.+++++.+++. ++++.......  .+..+....++++++. .+++
T Consensus       119 ~~~~~~~~~l~~~~~~~~~i~~l~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~  195 (297)
T 4JOQ_A          119 GFGRVAGEYFAQHLESGKKIVVLRGIPTTLDNERVEAFTAAIEGS-GIEVLDMQHGN--WNRDDAFNVMQDFLSKYPQID  195 (297)
T ss_dssp             HHHHHHHHHHHHHCCTTCEEEEEECSSSHHHHHHHHHHHHHTTTS-CCEEEEEEECT--TCHHHHHHHHHHHHHHCSCCC
T ss_pred             HHHHHHHHHHHHHccCCCEEEEEECCCCChHHHHHHHHHHHHhcC-CcEEeecccCC--CCHHHHHHHHHHHHHhCCCCC
Confidence            7788888887554  67889988844 345566777888877765 35443221111  1122344455555421 2366


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++.. +..+..+++++++.|+..++.+++.
T Consensus       196 ~i~~~~-~~~a~~~~~~l~~~g~~~~~~v~g~  226 (297)
T 4JOQ_A          196 AVWAAD-DDMAIGAMEAIAQAGRTEEMWVMGG  226 (297)
T ss_dssp             EEECCS-HHHHHHHHHHHHHTTCGGGCEEECC
T ss_pred             EEEECC-hHHHHHHHHHHHHCCCCCCcEEEec
Confidence            666553 4446677788887776323444443


No 144
>4JOQ_B ABC ribose transporter, periplasmic solute-binding; structural genomics, ribose, ABC transporter; HET: MSE; 1.9A {Rhodobacter sphaeroides}
Probab=97.56  E-value=6.4e-08  Score=97.68  Aligned_cols=218  Identities=11%  Similarity=0.018  Sum_probs=129.3  Template_Neff=12.000

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++.....+++.+++++|+.+     ..+++.+.++ .++    ....+.++
T Consensus         4 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~~~~~-----~~~~~~~~~~-~~~----~~~~~~~~   61 (297)
T 4JOQ_B            4 QEKVGTIGIAIPSATH------------GFMGGLNFHAQDTIKRLQEVY-----PQLDFVLATA-GNA----GKMVNDIE   61 (297)
T ss_dssp             CCCCEEEEEEEECCSS------------HHHHHHHHHHHHHHHHHHHHC-----TTEEEEEEEE-SSH----HHHHHHHH
T ss_pred             cccceEEEEEeccCCC------------hhHHHHHHHHHHHHHHHHHHc-----ccccEEEEcC-CCH----HHHHHHHH
Confidence            4578999999997642            256677889999999988643     1344444444 222    12223334


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                  .++++++|+...+.... .....+...++|+|..+...+.     ..++.+++.+++.
T Consensus        62 ~l~~------------------~~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~-----~~~~~~~v~~d~~  118 (297)
T 4JOQ_B           62 DMVA------------------TRNISALVVLPFESEPLTSPVQAVKEAGIWVTVVDRGLSV-----EGIEDLYVAGDNP  118 (297)
T ss_dssp             HHHH------------------HHCCSEEEECCSSHHHHHHHHHHHHHTTCEEEEESSCCSS-----TTCCSEEEEECHH
T ss_pred             HHHH------------------hCCCCEEEEcCCCCCCCcHHHHHHHHcCCEEEEEeCCCCC-----CCceeEEEEcCch
Confidence            3332                  14788888765444322 3445566789999987764431     1345677778887


Q NP_000836.2     201 YQAQAMVDIVTAL--GWNYVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~--~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ..++.+++++.+.  +.++++++..+ ..++..+.+++++.+++. ++++.......  .+..+....++++++. .+++
T Consensus       119 ~~~~~~~~~l~~~~~~~~~i~~l~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~  195 (297)
T 4JOQ_B          119 GFGRVAGEYFAQHLESGKKIVVLRGIPTTLDNERVEAFTAAIEGS-GIEVLDMQHGN--WNRDDAFNVMQDFLSKYPQID  195 (297)
T ss_dssp             HHHHHHHHHHHHHCCTTCEEEEEECSSSHHHHHHHHHHHHHHTTS-CCEEEEEEECT--TCHHHHHHHHHHHHHHCSCCC
T ss_pred             HHHHHHHHHHHHHccCCCEEEEEECCCCChHHHHHHHHHHHHhcC-CcEEeecccCC--CCHHHHHHHHHHHHHhCCCCC
Confidence            7788888887554  67889988844 345566777888877765 35443221111  1122344455555421 2366


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++.. +..+..+++++++.|+..++.+++.
T Consensus       196 ~i~~~~-~~~a~~~~~~l~~~g~~~~~~v~g~  226 (297)
T 4JOQ_B          196 AVWAAD-DDMAIGAMEAIAQAGRTEEMWVMGG  226 (297)
T ss_dssp             EEECCS-HHHHHHHHHHHHHTTCGGGCEEECC
T ss_pred             EEEECC-hHHHHHHHHHHHHCCCCCCcEEEec
Confidence            666553 4446677788887776323444443


No 145
>5HSG_A Putative ABC transporter, nucleotide binding/ATPase; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: MSE; 1.3A {Klebsiella pneumoniae subsp. pneumoniae}
Probab=97.54  E-value=7e-08  Score=98.22  Aligned_cols=214  Identities=10%  Similarity=0.040  Sum_probs=121.8  Template_Neff=11.600

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...+.++||++.|..+.            .++.....+++.++++.|          +++.+.|+..++.    ...+.+
T Consensus        21 ~~~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~   74 (310)
T 5HSG_A           21 QSMAGPTYALVQINQQA------------LFFNLMNKGAQDAAKASG----------KDLVIFNSNDNPV----AQNDAI   74 (310)
T ss_dssp             ----CCSEEEEESCSSS------------HHHHHHHHHHHHHHHHTT----------CCEEEEECTTCHH----HHHHHH
T ss_pred             ccCCCCEEEEEEecCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCHH----HHHHHH
Confidence            44578999999997642            255677788888887653          3344455443322    223344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      ++++.                   .+++++|+...+... ......+...++|+|..+...+.      .+..+++.+++
T Consensus        75 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~d~  129 (310)
T 5HSG_A           75 ENYIQ-------------------QGVKGILVAAIDVNGIMPAVKEAAAANIPVIAIDAVLPA------GPQAAQVGVDN  129 (310)
T ss_dssp             HHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCCS------SSCSEEEECCH
T ss_pred             HHHHH-------------------cCCCEEEEeCCCccccHHHHHHHHHCCCCEEEEccCCCC------CCcceEEEcCh
Confidence            44332                   477877765443322 23445566789999987654331      24566777777


Q NP_000836.2     200 SYQAQAMVDIVTAL------GWNYVSTLAS-EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-  271 (908)
Q Consensus       200 ~~~~~~~~~~l~~~------~~~~v~ii~~-~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-  271 (908)
                      ...++.+++++.+.      +.++++++.. ++.++..+.++|++.+++.+...+.......  .+..+....+++++. 
T Consensus       130 ~~~~~~~~~~l~~~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~  207 (310)
T 5HSG_A          130 IEGGRIIGQYFVDYVQKEMGGQARLGIVGALNSAIQNQRQKGFEETLKSNPKITIANVVDGQ--NVQDKAMTAAENLITG  207 (310)
T ss_dssp             HHHHHHHHHHHHHHHHHHSTTCEEEEEEECTTCHHHHHHHHHHHHHHTTCTTEEEC-CEECT--TCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHhCCceEEEEEecCCcHHHHHHHHHHHHHHHhCCCcEEeEeecCC--CCHHHHHHHHHHHHhh
Confidence            77777777776544      7789999875 4455667778888887764213332211111  111233445555542 


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ..++++|++.. +..+..+++++++.|...++.+++.
T Consensus       208 ~~~~~~i~~~~-~~~a~~~~~~~~~~g~~~~i~v~~~  243 (310)
T 5HSG_A          208 NPDLTAIYATG-EPALLGAIAAVENQGRQKDIKVFGW  243 (310)
T ss_dssp             CTTCCEEEESS-HHHHHHHHHHHHHTTCTTTCEEEEE
T ss_pred             CCCcCEEEEcC-chHHHHHHHHHHHCCCCCCeEEEEe
Confidence            12466666553 4456678888887776323444443


No 146
>2O20_B Catabolite control protein A; ccpa, transcriptional regulator, helix-turn-helix, TRANSCRIPTION; HET: SO4; 1.9A {Lactococcus lactis}
Probab=97.51  E-value=8.3e-08  Score=98.76  Aligned_cols=203  Identities=9%  Similarity=0.059  Sum_probs=122.1  Template_Neff=11.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++.....+++.++++.+          +++.+.|...++    +...+.++
T Consensus        60 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  113 (332)
T 2O20_B           60 SKRTTTVGVILPTITS------------TYFAAITRGVDDIASMYK----------YNMILANSDNDV----EKEEKVLE  113 (332)
T ss_dssp             ---CCEEEEEESCTTC------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHHH
T ss_pred             hCCCCEEEEEeCCCCC------------hhHHHHHHHHHHHHHHcC----------CEEEEEeCCCCH----HHHHHHHH
Confidence            3568899999987542            255677788888777642          234444544332    22333344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   ++++++|+...+... .....+...++|+|..+...+       .++.+.+..++..
T Consensus       114 ~~~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  166 (332)
T 2O20_B          114 TFLS-------------------KQVDGIVYMGSSLDE-KIRTSLKNSRTPVVLVGTIDG-------DKEIPSVNIDYHL  166 (332)
T ss_dssp             HHHH-------------------TTCSEEEEESSSCCH-HHHHHHHHHTCCEEEESCCCT-------TSCSCEEEECHHH
T ss_pred             HHHh-------------------CCCCEEEEeCCCCCH-HHHHHHHhCCCCEEEEcCCCC-------CCCCCEEEeCHHH
Confidence            3332                   478888875544332 444556778999998765432       2345666777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      .++.+++++.+.+.++++++..  ++.++..+.++|++.+++. ++.+..........+..+....+++++. .++|+|+
T Consensus       167 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~d~i~  244 (332)
T 2O20_B          167 AAYQSTKKLIDSGNKKIAYIMGSLKDVENTERMVGYQEALLEA-NIEFDENLVFEGNYSYEQGKALAERLLE-RGATSAV  244 (332)
T ss_dssp             HHHHHHHHHHHTTCSSEEEECSCTTSHHHHHHHHHHHHHHHHH-TCCCCGGGEECSCCSHHHHHHHHHHHHH-TTCCEEE
T ss_pred             HHHHHHHHHHHcCCCcEEEEeCCCCcHHHHHHHHHHHHHHHHC-CCCCCHHHeeccCCCHHHHHHHHHHHHH-cCCCEEE
Confidence            7778888876668889999985  3345667788888888765 3443321111101112234455666653 4788887


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +.. +..+..+++++++.|+.
T Consensus       245 ~~~-~~~a~~~~~~l~~~g~~  264 (332)
T 2O20_B          245 VSH-DTVAVGLLSAMMDKGVK  264 (332)
T ss_dssp             ESC-HHHHHHHHHHHHHTTCC
T ss_pred             ECC-hHHHHHHHHHHHHCCCC
Confidence            654 44566778888887764


No 147
>2O20_F Catabolite control protein A; ccpa, transcriptional regulator, helix-turn-helix, TRANSCRIPTION; HET: SO4; 1.9A {Lactococcus lactis}
Probab=97.51  E-value=8.3e-08  Score=98.76  Aligned_cols=203  Identities=9%  Similarity=0.059  Sum_probs=123.3  Template_Neff=11.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++.....+++.++++.+          +++.+.|...++    +...+.++
T Consensus        60 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  113 (332)
T 2O20_F           60 SKRTTTVGVILPTITS------------TYFAAITRGVDDIASMYK----------YNMILANSDNDV----EKEEKVLE  113 (332)
T ss_dssp             -CCCCEEEEEESCTTC------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHHH
T ss_pred             hCCCCEEEEEeCCCCC------------hhHHHHHHHHHHHHHHcC----------CEEEEEeCCCCH----HHHHHHHH
Confidence            3568899999987542            255677788888777642          234444544332    22333344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   ++++++|+...+... .....+...++|+|..+...+       .++.+.+..++..
T Consensus       114 ~~~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  166 (332)
T 2O20_F          114 TFLS-------------------KQVDGIVYMGSSLDE-KIRTSLKNSRTPVVLVGTIDG-------DKEIPSVNIDYHL  166 (332)
T ss_dssp             HHHH-------------------TTCSEEEECSSCCCH-HHHHHHHHHTCCEEEESCCCT-------TSCSCEEEECHHH
T ss_pred             HHHh-------------------CCCCEEEEeCCCCCH-HHHHHHHhCCCCEEEEcCCCC-------CCCCCEEEeCHHH
Confidence            3332                   478888875544332 444556778999998765432       2345666777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      .++.+++++.+.+.++++++..  ++.++..+.++|++.+++. ++.+..........+..+....+++++. .++|+|+
T Consensus       167 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~d~i~  244 (332)
T 2O20_F          167 AAYQSTKKLIDSGNKKIAYIMGSLKDVENTERMVGYQEALLEA-NIEFDENLVFEGNYSYEQGKALAERLLE-RGATSAV  244 (332)
T ss_dssp             HHHHHHHHHHHTTCSSEEEECSCTTSHHHHHHHHHHHHHHHHT-TCCCCGGGEECSCCSHHHHHHHHHHHHH-TTCCEEE
T ss_pred             HHHHHHHHHHHcCCCcEEEEeCCCCcHHHHHHHHHHHHHHHHC-CCCCCHHHeeccCCCHHHHHHHHHHHHH-cCCCEEE
Confidence            7778888876668889999985  3345667788888888765 3443321111101112234455666653 4788887


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +.. +..+..+++++++.|+.
T Consensus       245 ~~~-~~~a~~~~~~l~~~g~~  264 (332)
T 2O20_F          245 VSH-DTVAVGLLSAMMDKGVK  264 (332)
T ss_dssp             ESS-HHHHHHHHHHHHHTTCC
T ss_pred             ECC-hHHHHHHHHHHHHCCCC
Confidence            654 44566778888887764


No 148
>4YO7_A Sugar ABC transporter (Sugar-binding protein); ENZYME FUNCTION INITIATIVE, EFI, Structural; HET: INS, MSE; 1.7A {Bacillus halodurans}
Probab=97.51  E-value=8.5e-08  Score=98.37  Aligned_cols=216  Identities=14%  Similarity=0.082  Sum_probs=126.6  Template_Neff=11.700

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++.++||++.|..+.             ++....++++.++++.|       +  +++.+.|+..++.    ...+.
T Consensus        40 ~~~~~~~~Igv~~~~~~~-------------~~~~~~~~~~~~~~~~~-------~--~~~~~~~~~~~~~----~~~~~   93 (326)
T 4YO7_A           40 TGDSGQKVIGVSISNLDE-------------FLTYMQDAMKEEAANYP-------D--FEFIFSDAQNDST----QQMAQ   93 (326)
T ss_dssp             CCCCCCEEEEEEESCCCH-------------HHHHHHHHHHHHHTTCT-------T--EEEEEEECTTCHH----HHHHH
T ss_pred             cccCCCeEEEEEECCccH-------------HHHHHHHHHHHHHHhCC-------C--CEEEEecCCCCHH----HHHHH
Confidence            456788999999987632             45567778888777754       2  3445555544422    23333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+... ......+...++|+|..+...+.     ..++++++.++
T Consensus        94 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~-----~~~~~~~v~~d  149 (326)
T 4YO7_A           94 VENFIS-------------------RNVDAIIVNPVDTTSAVDIVNMVNDAGIPIIIANRTFDG-----VDQATAFVGSE  149 (326)
T ss_dssp             HHHHHH-------------------HTCSEEEECCSCHHHHHHHHHHHHHHTCCEEEESCCCTT-----GGGSSEEEECC
T ss_pred             HHHHHh-------------------CCCCEEEEcCCCcchhHHHHHHHHHCCCCEEEEccCCCC-----CccccEEEccc
Confidence            443332                   467877765443332 24445566789999987654331     13456777777


Q NP_000836.2     199 DSYQAQAMVDIVTA--LGWNYVSTLASE--GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TP  273 (908)
Q Consensus       199 ~~~~~~~~~~~l~~--~~~~~v~ii~~~--~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~  273 (908)
                      +...++.+++++.+  .+.++++++..+  ..++..+.+++++.+++.+++++.......  .+..+....++++++ ..
T Consensus       150 ~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~  227 (326)
T 4YO7_A          150 SIQSGLLQMEEVAKLLNNEGNIAIMDGELGHEAQIMRTEGNKQIIEEHDGLEVVLQGTAK--FDRSEGMRLMENWLNSGT  227 (326)
T ss_dssp             HHHHHHHHHHHHHHHTTTCEEEEEEECSTTCHHHHHHHHHHHHHHHTCTTEEEEEEEECT--TCHHHHHHHHHHHHHTTC
T ss_pred             hHHHHHHHHHHHHHHhCCCceEEEEECCCCCHHHHHHHHHHHHHHHhCCCeeEEEeccCC--CCHHHHHHHHHHHHHhCC
Confidence            77777788887755  467899999853  235667777888877654223433211111  111233444555542 13


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|+|+... +..+..+++++++.|...++.+++.
T Consensus       228 ~~d~i~~~~-~~~~~~~~~~l~~~g~~~~i~iv~~  261 (326)
T 4YO7_A          228 EIDAVVANN-DEMALGAILALEAVGKLDDVIVAGI  261 (326)
T ss_dssp             CCSEEEESS-HHHHHHHHHHHHHTTCGGGSEEECS
T ss_pred             CCCEEEECC-hHHHHHHHHHHHHCCCCCCeEEEEe
Confidence            577776654 4456678888888776323444444


No 149
>6GQ0_A Putative sugar binding protein; Glucose-galactose binding protein, Gebacillus stearothermophilus; 1.94A {Geobacillus stearothermophilus}
Probab=97.49  E-value=9.5e-08  Score=97.65  Aligned_cols=220  Identities=12%  Similarity=0.077  Sum_probs=123.4  Template_Neff=11.400

Q NP_000836.2      35 EYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALE  114 (908)
Q Consensus        35 ~~~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~  114 (908)
                      .........++++||++.|..+.            .++.....+++.++++.+        +++.+...+. .++    +
T Consensus        20 ~~~~~~~~~~~~~I~vv~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~   74 (318)
T 6GQ0_A           20 KERVPETTKEAYHFVLVPEELDN------------DYWRLVEKGAKAAAKELG--------VDLEYIGPRQ-ANI----D   74 (318)
T ss_dssp             --------CCCCEEEEECSCSSC------------HHHHHHHHHHHHHHHHHT--------CEEEECCCSS-CCH----H
T ss_pred             ccCCCCCCCCcEEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC--------CEEEEECCCc-cCH----H
Confidence            33444567788999999885432            245677788888887753        3444443322 221    1


Q NP_000836.2     115 QSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFS  193 (908)
Q Consensus       115 ~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~  193 (908)
                      ...+.+++++.                   ++++++|+...+.... .....+...++|+|..+...+.      .++++
T Consensus        75 ~~~~~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~  129 (318)
T 6GQ0_A           75 EHLRILKKAAA-------------------AKVDGIITQGLTEAEFVPVINEITDKNIPVVTIDTDAPT------SRRVA  129 (318)
T ss_dssp             HHHHHHHHHHH-------------------TTCSEEEECCCBHHHHHHHHHHHHTTTCCEEEESSCCTT------SCCSE
T ss_pred             HHHHHHHHHHH-------------------CCCCEEEECCCCHHHhHHHHHHHHHCCCCEEEEeCCCCc------ccceE
Confidence            22333443332                   4788887654433221 3344566679999987654321      24567


Q NP_000836.2     194 RVVPPDSYQAQAMVDIVTA--LGWNYVSTLASEGN--YGESGVEAFTQISRE-IGGVCIAQSQKIPREPRPGEFEKIIKR  268 (908)
Q Consensus       194 ~~~~~~~~~~~~~~~~l~~--~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~-~~~i~v~~~~~~~~~~~~~~~~~~~~~  268 (908)
                      ++.+++...+..+++++.+  .+.++++++..+..  ++..+.+++++.+++ . ++.+.......  .+..+....+.+
T Consensus       130 ~v~~~~~~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~  206 (318)
T 6GQ0_A          130 YVGTDNYYAGFLAGRALAEDTKGKATVAIITGSLTAAHQQLRVRGFEDAVRQEK-GIRIVAIEESH--ITRVQAAEKAYT  206 (318)
T ss_dssp             EEEECHHHHHHHHHHHHHHHTTTCEEEEEEESCSSBHHHHHHHHHHHHHHTTCT-TEEEEEEEECT--TCHHHHHHHHHH
T ss_pred             EEEcChHHHHHHHHHHHHHHcCCCcEEEEEECCCCcHHHHHHHHHHHHHHHhcC-CeEEEEEEecC--CCHHHHHHHHHH
Confidence            7777777778888888765  57889999985433  455677777777765 3 34443211111  111223344455


Q NP_000836.2     269 LLET-PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       269 l~~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +++. .++++|++.. +..+..+++++++.|+..++.+++.
T Consensus       207 ~l~~~~~~~~i~~~~-~~~a~~~~~~l~~~g~~~~i~i~~~  246 (318)
T 6GQ0_A          207 ILKKHPDVNAFYGTS-ALDAIGVAKVVEQFHREQKTYIIGF  246 (318)
T ss_dssp             HHHHCTTCCEEEECS-TTHHHHHHHHHHHTTCGGGCEEEEE
T ss_pred             HHHHCCCcCEEEEcC-cchHHHHHHHHHHcCCCCCeEEEEe
Confidence            5421 2678876665 3556678888887776323444443


No 150
>6GT9_C Putative sugar binding protein; Glucose-galactose binding protein, Geobacillus stearothermophilus; HET: SO4, GAL; 1.894A {Geobacillus stearothermophilus}
Probab=97.49  E-value=9.5e-08  Score=97.65  Aligned_cols=220  Identities=12%  Similarity=0.077  Sum_probs=125.3  Template_Neff=11.400

Q NP_000836.2      35 EYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALE  114 (908)
Q Consensus        35 ~~~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~  114 (908)
                      .........++++||++.|..+.            .++.....+++.++++.+        +++.+...+. .++    +
T Consensus        20 ~~~~~~~~~~~~~I~vv~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~   74 (318)
T 6GT9_C           20 KERVPETTKEAYHFVLVPEELDN------------DYWRLVEKGAKAAAKELG--------VDLEYIGPRQ-ANI----D   74 (318)
T ss_dssp             -----CCSTTSCEEEEECSSTTC------------HHHHHHHHHHHHHHHHHT--------CEEEECCCSS-CCH----H
T ss_pred             ccCCCCCCCCcEEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC--------CEEEEECCCc-cCH----H
Confidence            33444567788999999885432            245677788888887753        3444443322 221    1


Q NP_000836.2     115 QSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFS  193 (908)
Q Consensus       115 ~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~  193 (908)
                      ...+.+++++.                   ++++++|+...+.... .....+...++|+|..+...+.      .++++
T Consensus        75 ~~~~~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~  129 (318)
T 6GT9_C           75 EHLRILKKAAA-------------------AKVDGIITQGLTEAEFVPVINEITDKNIPVVTIDTDAPT------SRRVA  129 (318)
T ss_dssp             HHHHHHHHHHH-------------------TTCSEEEECCCCHHHHHHHHHHHHHTTCCEEEESSCCTT------SCCSE
T ss_pred             HHHHHHHHHHH-------------------CCCCEEEECCCCHHHhHHHHHHHHHCCCCEEEEeCCCCc------ccceE
Confidence            22333443332                   4788887654433221 3344566679999987654321      24567


Q NP_000836.2     194 RVVPPDSYQAQAMVDIVTA--LGWNYVSTLASEGN--YGESGVEAFTQISRE-IGGVCIAQSQKIPREPRPGEFEKIIKR  268 (908)
Q Consensus       194 ~~~~~~~~~~~~~~~~l~~--~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~-~~~i~v~~~~~~~~~~~~~~~~~~~~~  268 (908)
                      ++.+++...+..+++++.+  .+.++++++..+..  ++..+.+++++.+++ . ++.+.......  .+..+....+.+
T Consensus       130 ~v~~~~~~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~  206 (318)
T 6GT9_C          130 YVGTDNYYAGFLAGRALAEDTKGKATVAIITGSLTAAHQQLRVRGFEDAVRQEK-GIRIVAIEESH--ITRVQAAEKAYT  206 (318)
T ss_dssp             EEECCHHHHHHHHHHHHHHHTTTEEEEEEEESCSSCHHHHHHHHHHHHHHTTCT-EEEEEEEEECT--TCHHHHHHHHHH
T ss_pred             EEEcChHHHHHHHHHHHHHHcCCCcEEEEEECCCCcHHHHHHHHHHHHHHHhcC-CeEEEEEEecC--CCHHHHHHHHHH
Confidence            7777777778888888765  57889999985433  455677777777765 3 34443211111  111223344455


Q NP_000836.2     269 LLET-PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       269 l~~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +++. .++++|++.. +..+..+++++++.|+..++.+++.
T Consensus       207 ~l~~~~~~~~i~~~~-~~~a~~~~~~l~~~g~~~~i~i~~~  246 (318)
T 6GT9_C          207 ILKKHPDVNAFYGTS-ALDAIGVAKVVEQFHREQKTYIIGF  246 (318)
T ss_dssp             HHHHCTTCCEEEECS-TTHHHHHHHHHHHHCCSSCCEEEEE
T ss_pred             HHHHCCCcCEEEEcC-cchHHHHHHHHHHcCCCCCeEEEEe
Confidence            5421 2678876665 3556678888887776323444443


No 151
>1GUB_A D-ALLOSE-BINDING PERIPLASMIC PROTEIN; SUGAR-BINDING PROTEIN, PERIPLASMIC BINDING PROTEIN; 3.1A {ESCHERICHIA COLI} SCOP: c.93.1.1
Probab=97.48  E-value=1e-07  Score=95.59  Aligned_cols=218  Identities=11%  Similarity=0.073  Sum_probs=124.4  Template_Neff=12.200

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.        |+++.+...|+..++.    ...+.++++.
T Consensus         1 ~i~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~~~~~~~~~~~~~~----~~~~~~~~l~   56 (288)
T 1GUB_A            1 AAEYAVVLKTLSN------------PFWVDMKKGIEDEAKTL--------GVSVDIFASPSEGDFQ----SQLQLFEDLS   56 (288)
T ss_dssp             CCSEEEEESCSSS------------HHHHHHHHHHHHHHHHH--------TCCEEEEECSSTTCHH----HHHHHHHHHH
T ss_pred             CceEEEEEccCCC------------HHHHHHHHHHHHHHHHh--------CCEEEEEcCCCCCCHH----HHHHHHHHHH
Confidence            4789999987542            25567778888888775        3455555554333321    2233344333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSD-NTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~-~~~~~~~~~~~~~~~~~  202 (908)
                      .                   ++++++|+...+.... .....+...++|+|..+...+.... ....++++++.+++...
T Consensus        57 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~~~~~~~~~~~v~~~~~~~  117 (288)
T 1GUB_A           57 N-------------------KNYKGIAFAPLSSVNLVMPVARAWKKGIYLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAV  117 (288)
T ss_dssp             T-------------------SCCSEEEECCSSTTTTHHHHHHHHHHTCEEEEESSCCCHHHHHHHTCCCSEEEECCHHHH
T ss_pred             c-------------------CCCCEEEEecCCcccchHHHHHHHHCCCeEEEECCCCChHHHhhcCCceEEEEecChHHH
Confidence            2                   4788777654433221 3345566789999987764431100 00135667788888777


Q NP_000836.2     203 AQAMVDIVTAL-GW--NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       203 ~~~~~~~l~~~-~~--~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ++.+++++.+. +.  +++++++.  ++.++..+.+++++.+++.+.+.+.......  .+..+....++++++. .+++
T Consensus       118 ~~~~~~~l~~~~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~  195 (288)
T 1GUB_A          118 GAKGASFIIDKLGAEGGEVAIIEGKAGNASGEARRNGATEAFKKASQIKLVASQPAD--WDRIKALDVATNVLQRNPNIK  195 (288)
T ss_dssp             HHHHHHHHHHHHTTTCEEEEEECCCSSCHHHHHHHHHHHHHHHHCTTEEEEEEECCC--SCHHHHHHHHHHHHHHCTTEE
T ss_pred             HHHHHHHHHHHHhhCCceEEEEEcCCCCccHHHHHHHHHHHHHhcCCcEEeeccCCC--CcHHHHHHHHHHHHHHCCCcC
Confidence            88888887553 66  88999985  3345667778888887764213332211111  1112334445555421 2466


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++.. +..+..+++++++.|+..++.+++.
T Consensus       196 ~i~~~~-~~~~~~~~~~~~~~g~~~~~~i~~~  226 (288)
T 1GUB_A          196 AIYCAN-DTMAMGVAQAVANAGKTGKVLVVGT  226 (288)
T ss_dssp             EEEESS-HHHHHHHHHHHHHHTCBTTBEEEEE
T ss_pred             EEEECC-cccHHHHHHHHHHcCCCCCeEEEEe
Confidence            676654 4456678888888776323444444


No 152
>1GUD_B D-ALLOSE-BINDING PERIPLASMIC PROTEIN; PERIPLASMIC BINDING PROTEIN, ALLOSE, HINGE; 1.71A {ESCHERICHIA COLI} SCOP: c.93.1.1
Probab=97.48  E-value=1e-07  Score=95.59  Aligned_cols=218  Identities=11%  Similarity=0.073  Sum_probs=124.4  Template_Neff=12.200

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.        |+++.+...|+..++.    ...+.++++.
T Consensus         1 ~i~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~~~~~~~~~~~~~~----~~~~~~~~l~   56 (288)
T 1GUD_B            1 AAEYAVVLKTLSN------------PFWVDMKKGIEDEAKTL--------GVSVDIFASPSEGDFQ----SQLQLFEDLS   56 (288)
T ss_dssp             CCEEEEECSCSSS------------HHHHHHHHHHHHHHHHH--------TCEEEEECCSSTTCHH----HHHHHHHHHH
T ss_pred             CceEEEEEccCCC------------HHHHHHHHHHHHHHHHh--------CCEEEEEcCCCCCCHH----HHHHHHHHHH
Confidence            4789999987542            25567778888888775        3455555554333321    2233344333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSD-NTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~-~~~~~~~~~~~~~~~~~  202 (908)
                      .                   ++++++|+...+.... .....+...++|+|..+...+.... ....++++++.+++...
T Consensus        57 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~~~~~~~~~~~v~~~~~~~  117 (288)
T 1GUD_B           57 N-------------------KNYKGIAFAPLSSVNLVMPVARAWKKGIYLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAV  117 (288)
T ss_dssp             T-------------------TCCSEEEECCSSSSTTHHHHHHHHHTTCEEEEESSCCCHHHHHHTTCCCSEEEECCHHHH
T ss_pred             c-------------------CCCCEEEEecCCcccchHHHHHHHHCCCeEEEECCCCChHHHhhcCCceEEEEecChHHH
Confidence            2                   4788777654433221 3345566789999987764431100 00135667788888777


Q NP_000836.2     203 AQAMVDIVTAL-GW--NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       203 ~~~~~~~l~~~-~~--~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ++.+++++.+. +.  +++++++.  ++.++..+.+++++.+++.+.+.+.......  .+..+....++++++. .+++
T Consensus       118 ~~~~~~~l~~~~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~  195 (288)
T 1GUD_B          118 GAKGASFIIDKLGAEGGEVAIIEGKAGNASGEARRNGATEAFKKASQIKLVASQPAD--WDRIKALDVATNVLQRNPNIK  195 (288)
T ss_dssp             HHHHHHHHHHHHTTTCEEEEEEECSTTCHHHHHHHHHHHHHHHTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHCTTEE
T ss_pred             HHHHHHHHHHHHhhCCceEEEEEcCCCCccHHHHHHHHHHHHHhcCCcEEeeccCCC--CcHHHHHHHHHHHHHHCCCcC
Confidence            88888887553 66  88999985  3345667778888887764213332211111  1112334445555421 2466


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++.. +..+..+++++++.|+..++.+++.
T Consensus       196 ~i~~~~-~~~~~~~~~~~~~~g~~~~~~i~~~  226 (288)
T 1GUD_B          196 AIYCAN-DTMAMGVAQAVANAGKTGKVLVVGT  226 (288)
T ss_dssp             EEEESS-HHHHHHHHHHHHHTTCBTTBEEEEE
T ss_pred             EEEECC-cccHHHHHHHHHHcCCCCCeEEEEe
Confidence            676654 4456678888888776323444444


No 153
>1DBQ_B PURINE REPRESSOR; TRANSCRIPTION REGULATION, DNA-BINDING REGULATORY PROTEIN; 2.2A {Escherichia coli} SCOP: c.93.1.1
Probab=97.47  E-value=1.1e-07  Score=95.41  Aligned_cols=205  Identities=14%  Similarity=0.122  Sum_probs=114.3  Template_Neff=12.200

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++.....+++.++++.+          +++.+.|+..++    +...+.++
T Consensus         4 ~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~~----------~~~~~~~~~~~~----~~~~~~~~   57 (289)
T 1DBQ_B            4 VNHTKSIGLLATSSEA------------AYFAEIIEAVEKNCFQKG----------YTLILGNAWNNL----EKQRAYLS   57 (289)
T ss_dssp             ----CEEEEEESCSSC------------TTTTHHHHHHHHHHHHTT----------CEEEEEECSSCT----THHHHHHH
T ss_pred             cCCccEEEEEcCCCcc------------hHHHHHHHHHHHHHHHhC----------CeEEEEecCCCH----HHHHHHHH
Confidence            4567899999987542            245567777777776542          334445544332    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILR-LFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~-~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   .+++++|+...+... .....+. ..++|+|..+...+.      .++.+++.+++.
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~~~~  111 (289)
T 1DBQ_B           58 MMAQ-------------------KRVDGLLVMCSEYPE-PLLAMLEEYRHIPMVVMDWGEAK------ADFTDAVIDNAF  111 (289)
T ss_dssp             HHHH-------------------TTCSCCCEECSCCCH-HHHHHHHHTTTSCCCEEEESCCC------SSSCEEEECCHH
T ss_pred             HHHh-------------------cCCCEEEEecCCCCH-HHHHHHHHhCCCCEEEecCCCCC------CCCCcEEEeCHH
Confidence            3332                   478888875443322 2223333 479999987654321      234456667766


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ..++.+++++.+.+.++++++..  +..++..+.++|.+.+++. ++.+........+.+..+....++++++. .++++
T Consensus       112 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  190 (289)
T 1DBQ_B          112 EGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEA-MIKVPESWIVQGDFEPESGYRAMQQILSQPHRPTA  190 (289)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEECCC------CHHHHHHHHHHHHH-TCCCCGGGBCCCCSSHHHHHHHHHHHHSSSSCCSE
T ss_pred             HHHHHHHHHHHHCCCCcEEEEeCCCcccchHHHHHHHHHHHHHC-CCCCCHHHeeecCCChHHHHHHHHHHHcCCCCCCE
Confidence            77788888887668889999985  3345667778888887765 34443211111001112334445555431 24677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       191 v~~~~-~~~a~~~~~~l~~~g~~  212 (289)
T 1DBQ_B          191 VFCGG-DIMAMGALCAADEMGLR  212 (289)
T ss_dssp             EEESC-HHHHHHHHHHHHHHTCC
T ss_pred             EEECC-HHHHHHHHHHHHHcCCC
Confidence            76654 33566778888877764


No 154
>4RK0_D LacI family sugar-binding transcriptional regulator; sugar binding, transcription regulation, Enzyme; HET: RIB; 1.8A {Enterococcus faecalis V583}
Probab=97.45  E-value=1.2e-07  Score=94.24  Aligned_cols=198  Identities=12%  Similarity=0.122  Sum_probs=121.1  Template_Neff=12.100

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++..+..+++.++++.        |  +++.+.|+..++.    ...+.++
T Consensus         4 ~~~~~~I~~~~~~~~~------------~~~~~~~~g~~~~~~~~--------~--~~~~~~~~~~~~~----~~~~~~~   57 (274)
T 4RK0_D            4 MKKSKTIGVIVPDITN------------PFFAQLIRGIESVLYKE--------N--FILILCNADQDVT----REHEYLT   57 (274)
T ss_dssp             --CCEEEEEEESCTTS------------HHHHHHHHHHHHHHTTT--------T--EEEEEEEGGGCCS----TTCHHHH
T ss_pred             CCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHC--------C--CEEEEEeCCCChH----HHHHHHH
Confidence            4567899999987542            25667788888887764        2  3445555543322    2333444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+.....+...+...++|+|..+...+       .++.+++.+++..
T Consensus        58 ~~~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~~  111 (274)
T 4RK0_D           58 ELIR-------------------RSVDGFVIASSEISNQTINETLRAKKIPFIVLDQKKA-------EGFSDAVLTDDYR  111 (274)
T ss_dssp             HHHT-------------------SCCSEEEECCTTSCHHHCCCCCCHHTCCEEEETTSCC-------CSSSEEEEECHHH
T ss_pred             HHHH-------------------cCCCEEEEeCcccCchHHHHHHHHCCCCEEEEcCCCC-------CCCCcEEEechHH
Confidence            4332                   4788888765544333444556778999998765432       1356677788877


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      .++.+++++.+.+.++++++..+..  ++..+.++|++.+++. +..+..  .+.    ..+....+++++. .++|+|+
T Consensus       112 ~~~~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~--~~~----~~~~~~~~~~~~~-~~~~~i~  183 (274)
T 4RK0_D          112 GGQLAAKHLQEQRHEQVIVVMPPHAPVNIQQRLKGFCSVYTEK-VQLIET--ELS----KTGGYQAVPEILK-TESTGIF  183 (274)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEECSSCCHHHHHHHHHHHTTCCSS-EEEEEC--CSS----HHHHHHHHHHHHT-SCCCEEE
T ss_pred             HHHHHHHHHHHCCCCeEEEeCCCCCchHHHHHHHHHHHHHHhc-cceecc--ccc----ccchhhHHHHHHh-cCCCEEE
Confidence            8888888886666788999885433  5566777888777664 222111  111    1123344555553 3788887


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +.. +..+..+++++++.|+.
T Consensus       184 ~~~-~~~~~~~~~~~~~~g~~  203 (274)
T 4RK0_D          184 AIN-DEIAFGLYRGLAEAGKK  203 (274)
T ss_dssp             ESS-HHHHHHHHHHHHHTTCC
T ss_pred             EcC-hHHHHHHHHHHHHcCCC
Confidence            764 33466788888877764


No 155
>3DBI_A SUGAR-BINDING TRANSCRIPTIONAL REGULATOR, LACI FAMILY; STRUCTURAL GENOMICS, SUGAR-BINDING TRANSCRIPTIONAL REGULATOR; HET: MSE, PO4; 2.45A {Escherichia coli K12}
Probab=97.45  E-value=1.3e-07  Score=97.60  Aligned_cols=207  Identities=10%  Similarity=0.026  Sum_probs=121.5  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|..+..          ..++.....+++.++++.+          +++.+.|+..++    +...+.++
T Consensus        58 ~~~~~~Ig~i~~~~~~~----------~~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  113 (338)
T 3DBI_A           58 AKSTQTLGLVVTNTLYH----------GIYFSELLFHAARMAEEKG----------RQLLLADGKHSA----EEERQAIQ  113 (338)
T ss_dssp             --CCSEEEEEECTTTTS----------TTHHHHHHHHHHHHHHHTT----------CEEEEEECTTSH----HHHHHHHH
T ss_pred             cCCCCeEEEEecCcccc----------CccHHHHHHHHHHHHHHcC----------CEEEEEcCCCCH----HHHHHHHH
Confidence            35688999999976421          1255667778887777642          344455554442    22333444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .+++++|+...+.....+...++..++|+|.++...+.       +..+.+..++..
T Consensus       114 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-------~~~~~v~~~~~~  167 (338)
T 3DBI_A          114 YLLD-------------------LRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRK-------NSSHSVWCDHKQ  167 (338)
T ss_dssp             HHHH-------------------TTCSEEEECCSSSCHHHHHHHHHHCSSCEEEESSCCSS-------SGGGEECBCHHH
T ss_pred             HHHh-------------------cCCCEEEEeCCCCChHHHHHHHHhcCCCEEEECCCCCC-------CCCcEEEeCCHH
Confidence            4432                   47888887654433334445566789999987754321       234555666666


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .+..+++++.+.+.++++++..+..  ++..+.++|++.+++. ++.+.....+..+.+..+..+.+++++. ..++|+|
T Consensus       168 ~~~~~~~~l~~~g~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d~v  246 (338)
T 3DBI_A          168 TSFNAVAELINAGHQEIAFLTGSMDSPTSIERLAGYKDALAQH-GIALNEKLIANGKWTPASGAEGVEMLLERGAKFSAL  246 (338)
T ss_dssp             HHHHHHHHHHHTTCCSEEEECCCTTCHHHHHHHHHHHHHHHHT-TCCCCGGGEECCCSSHHHHHHHHHHHHHTTCCCSEE
T ss_pred             HHHHHHHHHHHCCCCcEEEEecCCCCchHHHHHHHHHHHHHHC-CCCCCHHHeecCCCChHHHHHHHHHHHHCCCCCCEE
Confidence            6777777776668889999986443  5667778888888765 3444321111100112233444555542 1247777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       247 ~~~~-~~~a~~~~~~l~~~g~~  267 (338)
T 3DBI_A          247 VASN-DDMAIGAMKALHERGVA  267 (338)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHCCCC
Confidence            7664 44567778888887764


No 156
>3DBI_C SUGAR-BINDING TRANSCRIPTIONAL REGULATOR, LACI FAMILY; STRUCTURAL GENOMICS, SUGAR-BINDING TRANSCRIPTIONAL REGULATOR; HET: MSE, PO4; 2.45A {Escherichia coli K12}
Probab=97.45  E-value=1.3e-07  Score=97.60  Aligned_cols=207  Identities=10%  Similarity=0.026  Sum_probs=121.5  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|..+..          ..++.....+++.++++.+          +++.+.|+..++    +...+.++
T Consensus        58 ~~~~~~Ig~i~~~~~~~----------~~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  113 (338)
T 3DBI_C           58 AKSTQTLGLVVTNTLYH----------GIYFSELLFHAARMAEEKG----------RQLLLADGKHSA----EEERQAIQ  113 (338)
T ss_dssp             --CCSEEEEEECTTTTS----------SSHHHHHHHHHHHHHHHTT----------CEEEEEECTTSH----HHHHHHHH
T ss_pred             cCCCCeEEEEecCcccc----------CccHHHHHHHHHHHHHHcC----------CEEEEEcCCCCH----HHHHHHHH
Confidence            35688999999976421          1255667778887777642          344455554442    22333444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .+++++|+...+.....+...++..++|+|.++...+.       +..+.+..++..
T Consensus       114 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-------~~~~~v~~~~~~  167 (338)
T 3DBI_C          114 YLLD-------------------LRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRK-------NSSHSVWCDHKQ  167 (338)
T ss_dssp             HHHH-------------------TTCSEEEECCSSSCHHHHHHHHHHCSSCEEEESSCCSS-------SGGGEECBCHHH
T ss_pred             HHHh-------------------cCCCEEEEeCCCCChHHHHHHHHhcCCCEEEECCCCCC-------CCCcEEEeCCHH
Confidence            4432                   47888887654433334445566789999987754321       234555666666


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .+..+++++.+.+.++++++..+..  ++..+.++|++.+++. ++.+.....+..+.+..+..+.+++++. ..++|+|
T Consensus       168 ~~~~~~~~l~~~g~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d~v  246 (338)
T 3DBI_C          168 TSFNAVAELINAGHQEIAFLTGSMDSPTSIERLAGYKDALAQH-GIALNEKLIANGKWTPASGAEGVEMLLERGAKFSAL  246 (338)
T ss_dssp             HHHHHHHHHHHTTCCSEEEECCCTTCHHHHHHHHHHHHHHHHT-TCCCCGGGEECCCSSHHHHHHHHHHHHHTTCCCSEE
T ss_pred             HHHHHHHHHHHCCCCcEEEEecCCCCchHHHHHHHHHHHHHHC-CCCCCHHHeecCCCChHHHHHHHHHHHHCCCCCCEE
Confidence            6777777776668889999986443  5667778888888765 3444321111100112233444555542 1247777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       247 ~~~~-~~~a~~~~~~l~~~g~~  267 (338)
T 3DBI_C          247 VASN-DDMAIGAMKALHERGVA  267 (338)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHCCCC
Confidence            7664 44567778888887764


No 157
>3EGC_F putative ribose operon repressor; STRUCTURAL GENOMICS, UNKNOWN FUNCTION, DNA-binding; 2.35A {Burkholderia thailandensis}
Probab=97.42  E-value=1.5e-07  Score=94.64  Aligned_cols=205  Identities=11%  Similarity=0.054  Sum_probs=119.7  Template_Neff=11.700

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++.++||++.|..+.            .++.....+++.++++.+          +++.+.++..++.    ...+.+
T Consensus         4 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~~----~~~~~~   57 (291)
T 3EGC_F            4 RSKRSNVVGLIVSDIEN------------VFFAEVASGVESEARHKG----------YSVLLANTAEDIV----REREAV   57 (291)
T ss_dssp             ---CCCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCHH----HHHHHH
T ss_pred             cCCCCcEEEEEEcCccc------------HHHHHHHHHHHHHHHHcC----------CeEEEEECCCCHH----HHHHHH
Confidence            34578999999987542            256677888888887753          2344445433321    223334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   .+++++|+...+.. ......+...++|+|..+...+       .++.+.+.++..
T Consensus        58 ~~l~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~  110 (291)
T 3EGC_F           58 GQFFE-------------------RRVDGLILAPSEGE-HDYLRTELPKTFPIVAVNRELR-------IPGCGAVLSENV  110 (291)
T ss_dssp             HHHHH-------------------TTCSEEEECCCSSC-CHHHHHSSCTTSCEEEESSCCC-------CTTCEEEEECHH
T ss_pred             HHHHH-------------------cCCCEEEEeCCCCC-hHHHHhhcCCCCCEEEECCCCC-------CCCCcEEEeCcH
Confidence            43332                   47888887654433 3344556678999998776433       134667777777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      ..++.+++++.+.+.++++++..  ++.....+.++|++.+++. ++++........+.+..+....+++++. ..++++
T Consensus       111 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~  189 (291)
T 3EGC_F          111 RGARTAVEYLIARGHTRIGAIVGSAGLMTSRERLKGFRAAMSAA-GLPVRQEWIAAGGVRADNGRDGAIKVLTGADRPTA  189 (291)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEECSSTTSHHHHHHHHHHHHHHHHT-TCCCCGGGEEC------CCHHHHHHHHTSTTCCSE
T ss_pred             HHHHHHHHHHHHCCCCcEEEEeCCCCcccHHHHHHHHHHHHHHc-CCCCChheEeecCCchhhHHHHHHHHHhCCCCCCE
Confidence            77778888876668889999985  3345566778888888765 3443321111100111122334444432 135777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       190 i~~~~-~~~a~~~~~~l~~~g~~  211 (291)
T 3EGC_F          190 LLTSS-HRITEGAMQALNVLGLR  211 (291)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHcCCC
Confidence            77664 44466777888877764


No 158
>4KZK_A L-arabinose-binding protein; L-arabinose, BETA-D-GALACTOSE, ABC transporter, periplasmic; HET: GAL; 1.5A {Burkholderia thailandensis}
Probab=97.41  E-value=1.6e-07  Score=96.80  Aligned_cols=218  Identities=11%  Similarity=0.069  Sum_probs=122.1  Template_Neff=11.900

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+.++||++.|..+.            .++.....+++.++++.+          +++.+.|+ .++    +...+.
T Consensus        31 ~~~~~~~~Ig~~~~~~~~------------~~~~~~~~~~~~a~~~~~----------~~~~~~~~-~~~----~~~~~~   83 (337)
T 4KZK_A           31 AQGAAPVKIGFVVKQPDD------------PWFQDEWRFAEQAAKDKH----------FTLVKIAA-PSG----EKVSTA   83 (337)
T ss_dssp             ------CEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT----------CEEEEEEC-CSH----HHHHHH
T ss_pred             hcCCCCeEEEEEECCCCC------------HHHHHHHHHHHHHHHHcC----------CEEEEEeC-CCH----HHHHHH
Confidence            455678999999985432            245667778888877652          33444454 332    222333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+.. .......+...++|+|.++...+.... ...++++++.++
T Consensus        84 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~-~~~~~~~~v~~d  143 (337)
T 4KZK_A           84 LDSLAA-------------------QKAQGVIICAPDVKLGPGIAAKAKRYGMKLMSVDDQLVDGRG-APLADVPHMGIS  143 (337)
T ss_dssp             HHHHHH-------------------TTCSEEEEECSSGGGHHHHHHHHHHTTCEEEEESSCCBCTTS-CBCTTSCEEEEC
T ss_pred             HHHHHh-------------------cCCCEEEEcCCCCcccHHHHHHHHHcCCEEEEEecCCCCCCC-CCcccCcEEecC
Confidence            443332                   47787776544332 233445667789999988765432111 113567777788


Q NP_000836.2     199 DSYQAQAMVDIVTA----LGWN--YVSTLASE---GNYGESGVEAFTQISREIGGVC---IAQSQKIPREPRPGEFEKII  266 (908)
Q Consensus       199 ~~~~~~~~~~~l~~----~~~~--~v~ii~~~---~~~~~~~~~~~~~~~~~~~~i~---v~~~~~~~~~~~~~~~~~~~  266 (908)
                      +...++.+++++.+    .+++  +++++..+   +.++..+.++|++.+++. +..   +.......  .+..+....+
T Consensus       144 ~~~~~~~~~~~l~~~~~~~g~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~--~~~~~~~~~~  220 (337)
T 4KZK_A          144 AYRIGRQVGDAIAAEAKRRGWNPAEVGVLRLAYDQLPTARERTTGAVDALKAA-GFAAANVVDAPEMT--ADTEGAFNAA  220 (337)
T ss_dssp             HHHHHHHHHHHHHHHHHHTTCCGGGCEEEEEECTTSHHHHHHHHHHHHHHHHT-TCCGGGEEEEECSS--SSHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHcCCCCccEEEEEecCCCChHHHHHHHHHHHHHHHc-CCccceeeccccCC--CCHHHHHHHH
Confidence            77778888887754    4666  89998754   456667788888888765 333   22111111  1122344555


Q NP_000836.2     267 KRLLETPNARA---VIMFANEDDIRRILEAAKKLNQSG-HFLWIGS  308 (908)
Q Consensus       267 ~~l~~~~~~~v---iv~~~~~~~~~~~l~~~~~~g~~~-~~~~i~~  308 (908)
                      +++++ .+++.   +++..++..+..+++++++.|+.. ++.+++.
T Consensus       221 ~~~~~-~~~~~~~~~i~~~~~~~a~~~~~~l~~~g~~~~~i~i~g~  265 (337)
T 4KZK_A          221 NIAFT-KHRNFRHWVAFGSNDDTTVGAVRAGEGRGIGTDDMIAVGI  265 (337)
T ss_dssp             HHHHH-HCTTCSSEEEECSSHHHHHHHHHHHHHTTCCGGGEEEEEE
T ss_pred             HHHHH-hCCCCCeEEEEecChHHHHHHHHHHHHcCCCCCCeEEEEe
Confidence            66653 34443   233334555677888888877631 3444443


No 159
>3O1I_C Sensor protein TorS (E.C.2.7.13.3), Periplasmic; Ligand free, Two component sensor; HET: PE4; 2.8A {Vibrio parahaemolyticus}
Probab=97.41  E-value=1.6e-07  Score=95.14  Aligned_cols=216  Identities=7%  Similarity=-0.002  Sum_probs=120.4  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||++.|....            ..+..+..+++.++++.+        +++.+...|...++.    ...+.+++
T Consensus         3 ~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~~~~~~----~~~~~~~~   58 (304)
T 3O1I_C            3 GSDEKICAIYPHLKD------------SYWLSVNYGMVSEAEKQG--------VNLRVLEAGGYPNKS----RQEQQLAL   58 (304)
T ss_dssp             --CCEEEEEESCSCS------------HHHHHHHHHHHHHHHHHT--------CEEEEEECSSTTCHH----HHHHHHHH
T ss_pred             CCCceEEEEEccCCC------------hHHHHHHHHHHHHHHHcC--------CEEEEEcCCCCCCHH----HHHHHHHH
Confidence            467899999987432            245677788888888753        455555444322321    22233443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   ++++++|+...+.. .......+. .++|+|..+...+... ....++.+++.++...
T Consensus        59 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~-~~ipvv~~~~~~~~~~-~~~~~~~~~v~~d~~~  117 (304)
T 3O1I_C           59 CTQ-------------------WGANAIILGTVDPHAYEHNLKSWV-GNTPVFATVNQLDLDE-EQSTLLKGEVGVDWYW  117 (304)
T ss_dssp             HHH-------------------HTCSEEEECCSSTTSSTTTHHHHT-TTSCEEECSSCCCCCT-TTGGGEEEECCCCHHH
T ss_pred             HHH-------------------hCCCEEEEcCCCHHhHHHHHHHHh-cCCCEEEEecCCCCCh-HHhhcceEEEEcChHH
Confidence            332                   47888877543322 223334455 6999988765433211 0113567788888877


Q NP_000836.2     202 QAQAMVDIVTAL-----GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       202 ~~~~~~~~l~~~-----~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      .++.+++++.+.     +.++++++..  +..++..+.+++++.+++. ++++.......  ....+....++++++..+
T Consensus       118 ~~~~~~~~l~~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~  194 (304)
T 3O1I_C          118 MGYEAGKYLAERHPKGSGKTNIALLLGPRTRGGTKPVTTGFYEAIKNS-DIHIVDSFWAD--NDKELQRNLVQRVIDMGN  194 (304)
T ss_dssp             HHHHHHHHHHTTSBTTTCCEEEEEECCCC-----CHHHHHHHHTTTTB-TEEEEECCCCC--SCHHHHHHHHHHHHHHSC
T ss_pred             HHHHHHHHHHHHCCCCCCCeEEEEEeCCCCCCcchHHHHHHHHHHhcC-CcEEeeeeecC--CCHHHHHHHHHHHHHcCC
Confidence            788888887554     6678999985  3335667788888888764 35443221111  111233344555542235


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +++|+.. ++ .+..+++++++.|+..++.+++.
T Consensus       195 ~~~i~~~-~~-~~~~~~~~~~~~g~~~~~~v~~~  226 (304)
T 3O1I_C          195 IDYIVGS-AV-AIEAAISELRSADKTHDIGLVSV  226 (304)
T ss_dssp             CSEEEEC-HH-HHHHHHHHHTTTTCGGGSEEBCS
T ss_pred             CCEEEEc-ch-HHHHHHHHHHHCCCCCCeEEEEE
Confidence            6666554 33 56778888887776323444443


No 160
>3O1I_D Sensor protein TorS (E.C.2.7.13.3), Periplasmic; Ligand free, Two component sensor; HET: PE4; 2.8A {Vibrio parahaemolyticus}
Probab=97.41  E-value=1.6e-07  Score=95.14  Aligned_cols=216  Identities=7%  Similarity=-0.002  Sum_probs=122.7  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||++.|....            ..+..+..+++.++++.+        +++.+...|...++.    ...+.+++
T Consensus         3 ~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~~~~~~----~~~~~~~~   58 (304)
T 3O1I_D            3 GSDEKICAIYPHLKD------------SYWLSVNYGMVSEAEKQG--------VNLRVLEAGGYPNKS----RQEQQLAL   58 (304)
T ss_dssp             --CCEEEEEESCSCS------------HHHHHHHHHHHHHHHTTT--------CEEEEEECSSTTCHH----HHHHHHHH
T ss_pred             CCCceEEEEEccCCC------------hHHHHHHHHHHHHHHHcC--------CEEEEEcCCCCCCHH----HHHHHHHH
Confidence            467899999987432            245677788888888753        455555444322321    22233443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   ++++++|+...+.. .......+. .++|+|..+...+... ....++.+++.++...
T Consensus        59 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~-~~ipvv~~~~~~~~~~-~~~~~~~~~v~~d~~~  117 (304)
T 3O1I_D           59 CTQ-------------------WGANAIILGTVDPHAYEHNLKSWV-GNTPVFATVNQLDLDE-EQSTLLKGEVGVDWYW  117 (304)
T ss_dssp             HHH-------------------HTCSEEEECCSCGGGSTTTTHHHH-TTCCEEECSSCCCCCT-TGGGGEEEECCCCTHH
T ss_pred             HHH-------------------hCCCEEEEcCCCHHhHHHHHHHHh-cCCCEEEEecCCCCCh-HHhhcceEEEEcChHH
Confidence            332                   47888877543322 223334455 6999988765433211 0113567788888877


Q NP_000836.2     202 QAQAMVDIVTAL-----GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       202 ~~~~~~~~l~~~-----~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      .++.+++++.+.     +.++++++..  +..++..+.+++++.+++. ++++.......  ....+....++++++..+
T Consensus       118 ~~~~~~~~l~~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~  194 (304)
T 3O1I_D          118 MGYEAGKYLAERHPKGSGKTNIALLLGPRTRGGTKPVTTGFYEAIKNS-DIHIVDSFWAD--NDKELQRNLVQRVIDMGN  194 (304)
T ss_dssp             HHHHHHHHHHTTSCTTSCCEEEEEECCSSSTTTSHHHHHHHHHHHHSS-SEEEEEECCCC--SCHHHHHHHHHHHHHHSC
T ss_pred             HHHHHHHHHHHHCCCCCCCeEEEEEeCCCCCCcchHHHHHHHHHHhcC-CcEEeeeeecC--CCHHHHHHHHHHHHHcCC
Confidence            788888887554     6678999985  3335667788888888764 35443221111  111233344555542235


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +++|+.. ++ .+..+++++++.|+..++.+++.
T Consensus       195 ~~~i~~~-~~-~~~~~~~~~~~~g~~~~~~v~~~  226 (304)
T 3O1I_D          195 IDYIVGS-AV-AIEAAISELRSADKTHDIGLVSV  226 (304)
T ss_dssp             CSEEEEC-HH-HHHHHHHHHHHTTCTTTSEEEES
T ss_pred             CCEEEEc-ch-HHHHHHHHHHHCCCCCCeEEEEE
Confidence            6666554 33 56778888887776323444443


No 161
>3O1J_C Sensor protein TorS (E.C.2.7.13.3), Periplasmic; Isopropanol bound, Two component sensor; 2.95A {Vibrio parahaemolyticus}
Probab=97.41  E-value=1.6e-07  Score=95.14  Aligned_cols=216  Identities=7%  Similarity=-0.002  Sum_probs=120.7  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||++.|....            ..+..+..+++.++++.+        +++.+...|...++.    ...+.+++
T Consensus         3 ~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~~~~~~----~~~~~~~~   58 (304)
T 3O1J_C            3 GSDEKICAIYPHLKD------------SYWLSVNYGMVSEAEKQG--------VNLRVLEAGGYPNKS----RQEQQLAL   58 (304)
T ss_dssp             --CCEEEEEESCSCS------------HHHHHHHHHHHHHHHHTT--------CEEEEEECSSTTCHH----HHHHHHHH
T ss_pred             CCCceEEEEEccCCC------------hHHHHHHHHHHHHHHHcC--------CEEEEEcCCCCCCHH----HHHHHHHH
Confidence            467899999987432            245677788888888753        455555444322321    22233443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   ++++++|+...+.. .......+. .++|+|..+...+... ....++.+++.++...
T Consensus        59 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~-~~ipvv~~~~~~~~~~-~~~~~~~~~v~~d~~~  117 (304)
T 3O1J_C           59 CTQ-------------------WGANAIILGTVDPHAYEHNLKSWV-GNTPVFATVNQLDLDE-EQSTLLKGEVGVDWYW  117 (304)
T ss_dssp             HHH-------------------HTCSEEEECCSSSSTTSSCSTTTT-TTCCEEECSSCCCCCH-HHHTTEEEEECCCHHH
T ss_pred             HHH-------------------hCCCEEEEcCCCHHhHHHHHHHHh-cCCCEEEEecCCCCCh-HHhhcceEEEEcChHH
Confidence            332                   47888877543322 223334455 6999988765433211 0113567788888877


Q NP_000836.2     202 QAQAMVDIVTAL-----GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       202 ~~~~~~~~l~~~-----~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      .++.+++++.+.     +.++++++..  +..++..+.+++++.+++. ++++.......  ....+....++++++..+
T Consensus       118 ~~~~~~~~l~~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~  194 (304)
T 3O1J_C          118 MGYEAGKYLAERHPKGSGKTNIALLLGPRTRGGTKPVTTGFYEAIKNS-DIHIVDSFWAD--NDKELQRNLVQRVIDMGN  194 (304)
T ss_dssp             HHHHHHHHHHHHSCTTSCCEEEEEEEECCC----THHHHHHHHHHSSS-SEEEEEEEECC--SCHHHHHHHHHHHHHTCC
T ss_pred             HHHHHHHHHHHHCCCCCCCeEEEEEeCCCCCCcchHHHHHHHHHHhcC-CcEEeeeeecC--CCHHHHHHHHHHHHHcCC
Confidence            788888887554     6678999985  3335667788888888764 35443221111  111233344555542235


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +++|+.. ++ .+..+++++++.|+..++.+++.
T Consensus       195 ~~~i~~~-~~-~~~~~~~~~~~~g~~~~~~v~~~  226 (304)
T 3O1J_C          195 IDYIVGS-AV-AIEAAISELRSADKTHDIGLVSV  226 (304)
T ss_dssp             CSEEEEC-HH-HHHHHHHHHHHTTCTTTSEEEES
T ss_pred             CCEEEEc-ch-HHHHHHHHHHHCCCCCCeEEEEE
Confidence            6666554 33 56778888887776323444443


No 162
>4YHS_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: MSE, BTB; 1.8A {Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)}
Probab=97.41  E-value=1.6e-07  Score=97.66  Aligned_cols=215  Identities=11%  Similarity=0.036  Sum_probs=122.9  Template_Neff=10.800

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+.++||++.|..+.            .++..+..+++.++++.        |+++.+...|+..++    ....+.
T Consensus        53 ~~~~~~~~Igvv~~~~~~------------~~~~~~~~g~~~a~~~~--------g~~l~~~~~~~~~~~----~~~~~~  108 (354)
T 4YHS_A           53 EKASKPWKLCVSFPHMKD------------AYWLGVDYGVAEESKRL--------GVKMNLVEAGGYTEL----NKQISQ  108 (354)
T ss_dssp             SCCSSCCEEEEEESCCCS------------HHHHHHHHHHHHHHHHH--------TCEEEEEECSSTTCH----HHHHHH
T ss_pred             ccCCCCeEEEEEeCCCCC------------HHHHHHHHHHHHHHHHh--------CCEEEEEecCCCCCH----HHHHHH
Confidence            345678999999987542            24567778888888774        345655555432232    122333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAA-ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+.. .+.........+.+.++|+|.++...+.      .++.+++.++
T Consensus       109 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d  163 (354)
T 4YHS_A          109 IEDCVA-------------------SGTDAVIIGAISADGLNKVIGEIAKKKIPVIDLVNGISS------PDIAAKSLVS  163 (354)
T ss_dssp             HHHHHH-------------------HCCSEEEECCSSSSTTHHHHHHHHTTTCCEEEESSCCCC------TTCCEEECCC
T ss_pred             HHHHHH-------------------cCCCEEEEcCCCHHhhHHHHHHHHhcCCCEEEEcCCCCC------hhhceEeecC
Confidence            444332                   4677776543 3322334455667789999987654321      2445667777


Q NP_000836.2     199 DSYQAQAMVDIVTAL---GWNYVSTLA----SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~---~~~~v~ii~----~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      ....++.+++++.+.   +.+++++++    .+..++..+.++|++.+++. ++.+.......  .+..+....++++++
T Consensus       164 ~~~~~~~~~~~l~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~g~~~~~~~~-g~~~~~~~~~~--~~~~~~~~~~~~~l~  240 (354)
T 4YHS_A          164 FYTMGAETGSYLAKKHPAGTPEVVVGWFPGPAGAGWVEAANKGFMDAVKGS-AIKVLEPKYGD--TGKEVQAKLVEDALQ  240 (354)
T ss_dssp             HHHHHHHHHHHHHHHSCTTSCCEEEEEECSSTTCHHHHHHHHHHHHHHTTS-SEEECCCCCCC--SCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHCCCCCCcEEEEEEcCCCCChHHHHHHHHHHHHHcCC-CcEEEccccCC--CCHHHHHHHHHHHHH
Confidence            777777888887654   778888863    12334566778888877764 35443221111  111233344555542


Q NP_000836.2     272 T-PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       272 ~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      . .++++|+..  +..+..+++++++.|+..++.+++.
T Consensus       241 ~~~~~~~i~~~--~~~a~~~~~~l~~~g~~~~v~i~g~  276 (354)
T 4YHS_A          241 AAPNIRYVAGT--AVTAEAAQGLIRERGLKGKVDLLAF  276 (354)
T ss_dssp             HCTTCCEEEEC--HHHHHHHHHHHHHTTCBTTBEEEES
T ss_pred             HCCCCCEEEEC--chHHHHHHHHHHHCCCCCCcEEEEE
Confidence            1 245555443  3456777888887776323334443


No 163
>3CLK_B Transcription regulator; 11017j, PSI-II, NYSGXRC, dimer, Structural; 2.08A {Lactobacillus plantarum WCFS1}
Probab=97.41  E-value=1.6e-07  Score=94.34  Aligned_cols=205  Identities=11%  Similarity=0.084  Sum_probs=114.7  Template_Neff=11.800

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++.++||++.|..+.            .++.....+++.++++.        |+++.+...+. .++    ....+.+
T Consensus         4 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~~~~~~~~~-~~~----~~~~~~~   58 (290)
T 3CLK_B            4 VKKSSNVIAAVVSSVRT------------NFAQQILDGIQEEAHKN--------GYNLIIVYSGS-ADP----EEQKHAL   58 (290)
T ss_dssp             ------CEEEEEC----------------CHHHHHHHHHHHHHTTT--------TCCEEEEC-----------CHHHHHH
T ss_pred             ccCCCCEEEEEECCCCC------------hHHHHHHHHHHHHHHHc--------CCeEEEEeCCC-CCH----HHHHHHH
Confidence            34568999999987542            25566778888887765        34454443332 221    1222333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   .++|++|+...+.. ......+...++|+|..+...+        +.++.+.+++.
T Consensus        59 ~~~~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ip~v~~~~~~~--------~~~~~v~~d~~  110 (290)
T 3CLK_B           59 LTAIE-------------------RPVMGILLLSIALT-DDNLQLLQSSDVPYCFLSMGFD--------DDRPFISSDDE  110 (290)
T ss_dssp             HHHHH-------------------SCCSEEEEESCCCC-HHHHHHHHHTTCCEEEESCCCS--------SSCCEEECCHH
T ss_pred             HHHHh-------------------CCCCEEEEecccCC-hHHHHHHHhCCCCEEEEccCCC--------CCCCEEeeCcH
Confidence            33332                   47888887654433 3444566778999998765432        24566777777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ..++.+++++.+.+.++++++..+..  ++..+.+++++.+++. ++.+........+.+..+....++++....++|+|
T Consensus       111 ~~~~~~~~~l~~~g~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d~i  189 (290)
T 3CLK_B          111 DIGYQATNLLINEGHRQIGIAGIDQYPYTGRKRLAGYKKALKEA-NIAINQEWIKPGDYSYTSGEQAMKAFGKNTDLTGI  189 (290)
T ss_dssp             HHHHHHHHHHHTTTCCSEEEESCCCSSHHHHHHHHHHHHHHHHT-TCCCCGGGEECCCSSHHHHHHHHHHHCTTCCCSEE
T ss_pred             HHHHHHHHHHHHCCCCCEEEEcCCCCCccchHHHHHHHHHHHHC-CCCCChhhccCCCCChhhHHHHHHHHhhCCCCCEE
Confidence            77888888887668889999985443  5566778888888765 34443211111001112233444444322467888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       190 ~~~~-~~~~~~~~~~l~~~g~~  210 (290)
T 3CLK_B          190 IAAS-DMTAIGILNQASSFGIE  210 (290)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHCCCC
Confidence            7664 33466778888877764


No 164
>2RGY_A Transcriptional regulator, LacI family; 11011j, NYSGXRC, Transctiptional regulator, LacI; 2.05A {Burkholderia phymatum}
Probab=97.40  E-value=1.6e-07  Score=94.18  Aligned_cols=208  Identities=13%  Similarity=0.021  Sum_probs=118.5  Template_Neff=12.000

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..+++++||++.|..+.            .++..+..+++.++++.        |+++.+...++..+.   .+...+.+
T Consensus         4 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~~~~~~~~~~~~~---~~~~~~~~   60 (290)
T 2RGY_A            4 ATQQLGIIGLFVPTFFG------------SYYGTILKQTDLELRAV--------HRHVVVATGCGESTP---REQALEAV   60 (290)
T ss_dssp             ----CCEEEEECSCSCS------------HHHHHHHHHHHHHHHHT--------TCEEEEECCCSSSCH---HHHHHHHH
T ss_pred             ccCCCceEEEEecCCCC------------chHHHHHHHHHHHHHHC--------CCeEEEEeCCCCCCh---HHHHHHHH
Confidence            44578999999997542            25566777877666653        344544433321111   11222333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +.+..                   .++|++|+...+... .....+.+.++|+|..+...+       .++.+++..++.
T Consensus        61 ~~~~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~  113 (290)
T 2RGY_A           61 RFLIG-------------------RDCDGVVVISHDLHD-EDLDELHRMHPKMVFLNRAFD-------ALPDASFCPDHR  113 (290)
T ss_dssp             HHHHH-------------------TTCSEEEECCSSSCH-HHHHHHHHHCSSEEEESSCCT-------TSGGGEECCCHH
T ss_pred             HHHhh-------------------CCCCEEEEEcCCCCH-HHHHHHHHcCCcEEEECCCCC-------CCCCceeecChH
Confidence            33322                   478888875544332 444556678999988765432       134566667777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNY--GESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~--~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ..+..+++++.+.+.++++++..+..+  +..+.+++++.+++. ++.+........+.+..+....+++++.. .++++
T Consensus       114 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~  192 (290)
T 2RGY_A          114 RGGELAAATLIEHGHRKLAVISGPFTASDNVERLDGFFDELARH-GIARDSVPLIESDFSPEGGYAATCQLLESKAPFTG  192 (290)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEEESCTTCHHHHHHHHHHHHHHHTT-TCCGGGSCEEECCSSHHHHHHHHHHHHHHTCCCSE
T ss_pred             HHHHHHHHHHHHCCCCeEEEEeCCCCCccHHHHHHHHHHHHHHC-CCCCCCCcEEEcCCChHHHHHHHHHHHhCCCCCCE
Confidence            777788888766688899999865433  556777888877764 34332111111001122334445555421 24788


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       193 i~~~~-~~~a~~~~~~l~~~g~~  214 (290)
T 2RGY_A          193 LFCAN-DTMAVSALARFQQLGIS  214 (290)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            87664 44567788888887764


No 165
>6HB0_A ABC transporter periplasmic-binding protein YtfQ; periplasmic binding protein, SUGAR BINDING; HET: ZN; 1.9A {Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)}
Probab=97.39  E-value=1.8e-07  Score=95.75  Aligned_cols=211  Identities=12%  Similarity=0.058  Sum_probs=120.2  Template_Neff=11.600

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....+.++||++.|..+.            .++.....+++.++++.|          +++.+.|+..++.    ...+
T Consensus        13 ~~~~~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~l~~~~~~~~~~----~~~~   66 (322)
T 6HB0_A           13 GSAPDGALTLGFAQVGAES------------GWRTANTESIKSAAEEAG----------VNLKFADANGEQE----KQIS   66 (322)
T ss_dssp             -----CCCEEEEEECC---------------CCSCCCHHHHHHHHHHHT----------CEEEEEECTTCHH----HHHH
T ss_pred             CCCCCCCeEEEEEeeCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEECCCCCHH----HHHH
Confidence            4566789999999997642            255667788888887753          3344555443322    2233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAAS-SVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s-~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   .+++++|....+ .........+...++|+|..+...+..   ...++.+++.+
T Consensus        67 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~---~~~~~~~~v~~  124 (322)
T 6HB0_A           67 AIRSFIQ-------------------QGVDVIAFSPVVRTGWDAVLQETKNAGIPVILTDRAVDTQ---DTDVYKTFIGA  124 (322)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCSSSSSCHHHHHHHHHTTCCEEEESSCCCCS---SSSSCSEEECC
T ss_pred             HHHHHHH-------------------cCCCEEEECCCCcccHHHHHHHHHHCCCCEEEECCCCCCC---CCchhceEEec
Confidence            3443332                   367766653332 222344455667899999877644321   11345677788


Q NP_000836.2     198 PDSYQAQAMVDIVTA-----LGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL  270 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~-----~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~  270 (908)
                      ++...++.+++++.+     .+.++++++..  ++.++..+.++|++.+++.+++++.......  .+..+....+++++
T Consensus       125 d~~~~~~~~~~~l~~~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~v~~~~~~~--~~~~~~~~~~~~~~  202 (322)
T 6HB0_A          125 DFIEEGRRAGQWVADQYASATGPVNIVQLEGTTGADPAIDRKTGFAEGISKNPNLKIVASQTGD--FTRSGGKQVMEAFL  202 (322)
T ss_dssp             CHHHHHHHHHHHHHHHTTTCSSCEEEEEEECSTTCHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TSHHHHHHHHHHHH
T ss_pred             ChHHHHHHHHHHHHHHHHhcCCCeEEEEEEcCCCCchHHHHHHHHHHHHhhCCCcEEEEeecCC--CCHHHHHHHHHHHH
Confidence            877778888887754     47789999985  3456667788888887764224443221111  11123344555554


Q NP_000836.2     271 E-TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       271 ~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      . ..++++|++.. +..+..+++++++.|+.
T Consensus       203 ~~~~~~d~i~~~~-~~~a~~~~~~~~~~g~~  232 (322)
T 6HB0_A          203 KSTPQIDVVFAQN-DDMGLGAMEAIEAAGKK  232 (322)
T ss_dssp             HHCSCCCEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             HHCCCcCEEEECC-HHHHHHHHHHHHHcCCC
Confidence            2 13567776654 34556778888877764


No 166
>1SXG_D Glucose-resistance amylase regulator; allosterism  phosphoprotein  transcription; HET: 171; 2.75A {Bacillus megaterium} SCOP: c.93.1.1
Probab=97.39  E-value=1.8e-07  Score=93.21  Aligned_cols=204  Identities=11%  Similarity=0.116  Sum_probs=120.8  Template_Neff=12.200

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++..+..+++.++++.+          +++.+.|+..++    +...+.++
T Consensus         5 ~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~   58 (280)
T 1SXG_D            5 SKKTTTVGVIIPDISN------------IFYAELARGIEDIATMYK----------YNIILSNSDQNQ----DKELHLLN   58 (280)
T ss_dssp             -CCCCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHHH
T ss_pred             CCCCCeEEEEeCCccc------------HHHHHHHHHHHHHHHHcC----------CeEEEeeCCCCH----HHHHHHHH
Confidence            4568999999987542            245667778887776642          334445544332    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+. .......+...++|+|..+...+       .++.+++.+++..
T Consensus        59 ~l~~-------------------~~~d~ii~~~~~~-~~~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~~  111 (280)
T 1SXG_D           59 NMLG-------------------KQVDGIIFMSGNV-TEEHVEELKKSPVPVVLAASIES-------TNQIPSVTIDYEQ  111 (280)
T ss_dssp             HHHH-------------------TCCSEEEECCSCC-CHHHHHHHHHCSSCEEEESCCCT-------TCCSCEEEECHHH
T ss_pred             HHHc-------------------CCCCEEEEeCCCC-CHHHHHHHHhCCCCEEEeCCCCC-------CCCCCeEEeChHH
Confidence            4332                   4788888755443 33444556678999998765322       2346677777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      .++.+++++.+.+.++++++..+..   .+..+.++|++.+++. ++.+.....+..+.+..+....+++++.. .++++
T Consensus       112 ~~~~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  190 (280)
T 1SXG_D          112 AAFDAVQSLIDSGHKNIAFVSGTLEEPINHAKKVKGYKRALTES-GLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPTA  190 (280)
T ss_dssp             HHHHHHHHHHTTSCSCEEEEESCTTSHCCCCCCHHHHHHHHHHT-TCCCCGGGEEECCSSHHHHHHHHHHHTTSSSCCSE
T ss_pred             HHHHHHHHHHHCCCCeEEEEeCCCCCcccHHHHHHHHHHHHHHc-CCCCCHHHeeecCCChhhHHHHHHHHHHcCCCCCE
Confidence            7888888876667889999985433   4556778888887765 34433221111001122334445555421 24677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       191 v~~~~-~~~~~~~~~~l~~~g~~  212 (280)
T 1SXG_D          191 IFVGT-DEMALGVIHGAQDRGLN  212 (280)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-hHHHHHHHHHHHHCCCC
Confidence            76654 34566777888877763


No 167
>2NZV_G Catabolite control protein, Phosphocarrier protein; CCpA, HPrser46-p, CCR, fructose-bis-phosphate, adjunct; HET: SEP, SO4, FBP; 3.0A {Bacillus megaterium} SCOP: c.93.1.1
Probab=97.39  E-value=1.8e-07  Score=93.21  Aligned_cols=204  Identities=11%  Similarity=0.116  Sum_probs=120.8  Template_Neff=12.200

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++..+..+++.++++.+          +++.+.|+..++    +...+.++
T Consensus         5 ~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~   58 (280)
T 2NZV_G            5 SKKTTTVGVIIPDISN------------IFYAELARGIEDIATMYK----------YNIILSNSDQNQ----DKELHLLN   58 (280)
T ss_dssp             -CCCSEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHHH
T ss_pred             CCCCCeEEEEeCCccc------------HHHHHHHHHHHHHHHHcC----------CeEEEeeCCCCH----HHHHHHHH
Confidence            4568999999987542            245667778887776642          334445544332    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+. .......+...++|+|..+...+       .++.+++.+++..
T Consensus        59 ~l~~-------------------~~~d~ii~~~~~~-~~~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~~  111 (280)
T 2NZV_G           59 NMLG-------------------KQVDGIIFMSGNV-TEEHVEELKKSPVPVVLAASIES-------TNQIPSVTIDYEQ  111 (280)
T ss_dssp             HHHH-------------------TCCSCEEECCSCC-CHHHHHHTTSCSSCEEEESCCCT-------TCCSCEEEECHHH
T ss_pred             HHHc-------------------CCCCEEEEeCCCC-CHHHHHHHHhCCCCEEEeCCCCC-------CCCCCeEEeChHH
Confidence            4332                   4788888755443 33444556678999998765322       2346677777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      .++.+++++.+.+.++++++..+..   .+..+.++|++.+++. ++.+.....+..+.+..+....+++++.. .++++
T Consensus       112 ~~~~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  190 (280)
T 2NZV_G          112 AAFDAVQSLIDSGHKNIAFVSGTLEEPINHAKKVKGYKRALTES-GLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPTA  190 (280)
T ss_dssp             HHHHHHHHHHHHHCSCEEEECSCTTSHHCCCCCCHHHHHHHHTT-CCCCCTTSEECCCSSHHHHHHHHHHHHTSSSCCSE
T ss_pred             HHHHHHHHHHHCCCCeEEEEeCCCCCcccHHHHHHHHHHHHHHc-CCCCCHHHeeecCCChhhHHHHHHHHHHcCCCCCE
Confidence            7888888876667889999985433   4556778888887765 34433221111001122334445555421 24677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       191 v~~~~-~~~~~~~~~~l~~~g~~  212 (280)
T 2NZV_G          191 IFVGT-DEMALGVIHGAQDRGLN  212 (280)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-hHHHHHHHHHHHHCCCC
Confidence            76654 34566777888877763


No 168
>4RS3_A ABC transporter, carbohydrate uptake transporter-2; SUGAR TRANSPORTER, ABC-TYPE, ENZYME FUNCTION; HET: XYL, MSE, IMD, ACT, ZN, CL; 1.4A {Mycobacterium smegmatis str. MC2 155}
Probab=97.37  E-value=1.9e-07  Score=95.69  Aligned_cols=213  Identities=13%  Similarity=0.075  Sum_probs=120.1  Template_Neff=11.500

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+.++||++.|..+.             ++.....+++.++++.+          +++.+.|+..++.    ...+.
T Consensus         7 ~~~~~~~~Ig~v~~~~~~-------------~~~~~~~g~~~~~~~~~----------~~l~~~~~~~~~~----~~~~~   59 (327)
T 4RS3_A            7 AANSDTKRIGVTVYDMSS-------------FITEGKEGMDTYAKANN----------IELVWNSANNDVS----TQASQ   59 (327)
T ss_dssp             -----CEEEEEEESCCCH-------------HHHHHHHHHHHHHHHTT----------EEEEEEECTTCHH----HHHHH
T ss_pred             cccCCCcEEEEEECCccH-------------HHHHHHHHHHHHHHHCC----------cEEEEecCCCCHH----HHHHH
Confidence            345678999999987532             44566777777776632          3445555543322    22333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+... ......+...++|+|.++...+.      .++++++.++
T Consensus        60 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d  114 (327)
T 4RS3_A           60 VDSLIN-------------------QGVDAIIVVPVQADSLGPQVASAKSKGIPLLAVNAALET------PDLAGNVQPD  114 (327)
T ss_dssp             HHHHHH-------------------HTCSEEEEECSCSSCCHHHHHHHHHTTCCEEEESSCCCC------TTCSEEEEEC
T ss_pred             HHHHHh-------------------CCCCEEEEecCCccccHHHHHHHHHCCCCEEEEcCCCCC------CCcceEecCC
Confidence            343332                   467877765443322 23344556679999987654321      2345677777


Q NP_000836.2     199 DSYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET--  272 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--  272 (908)
                      +...+..+++++.+.  +.++++++..  ++.++..+.++|++.+++.+++++.......  .+..+....++++++.  
T Consensus       115 ~~~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~  192 (327)
T 4RS3_A          115 DVAAGAQEMQMMADRLGGKGNIVILQGPLGGSGEINRGKGIDQVLAKYPDIKVLAKDTAN--WKRDEAVNKMKNWISSFG  192 (327)
T ss_dssp             HHHHHHHHHHHHHHHHTTCEEEEEEECSTTSHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHHG
T ss_pred             hHHHHHHHHHHHHHHhCCCcEEEEEECCCCChhHHHHHHHHHHHHHhCCCcEEEEeecCC--CCHHHHHHHHHHHHHHhc
Confidence            777777888887654  7789999885  3445666777888777664223332211111  1122344445555421  


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      .++++|++.. +..+..+++++++.|+. ++.+++.
T Consensus       193 ~~~~~i~~~~-~~~a~~~~~~l~~~g~~-~i~i~g~  226 (327)
T 4RS3_A          193 PQIDGVVAQN-DDMGLGALQALKEAGRT-GVPIVGI  226 (327)
T ss_dssp             GGCCEEEESS-HHHHHHHHHHHHHTTCC-CCCEECS
T ss_pred             CCCCEEEECC-hHHHHHHHHHHHHcCCC-CCCEEEe
Confidence            2377776664 44566788888887763 2344443


No 169
>5OCP_A Periplasmic binding protein/LacI transcriptional regulator; ABC transporter, periplasmic, binding protein; HET: FUB, GOL, AHR; 1.7A {Shewanella sp. ANA-3}
Probab=97.36  E-value=2e-07  Score=94.25  Aligned_cols=203  Identities=14%  Similarity=0.084  Sum_probs=118.2  Template_Neff=11.600

Q NP_000836.2      47 ILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIEK  126 (908)
Q Consensus        47 ~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~~~  126 (908)
                      +||+++|....            .++..+..+++.++++.+          +++.+.|+..++.    ...+.+++++. 
T Consensus         2 ~Igv~~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~l~~~~~~~~~~----~~~~~~~~l~~-   54 (302)
T 5OCP_A            2 TVGFSQVGSES------------GWRTSFSEAVKAEAKQRG----------IDLKFADAQQKQE----NQIKAVRSFIA-   54 (302)
T ss_dssp             EEEEEECCCSS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCHH----HHHHHHHHHHH-
T ss_pred             eEEEecCCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEecCCCCHH----HHHHHHHHHHH-
Confidence            67888764322            255677788888887642          3445555544322    22333443332 


Q NP_000836.2     127 DASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQA  205 (908)
Q Consensus       127 ~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~  205 (908)
                                        ++++++|+...+... ......+...++|+|..+...+..   ...++++++.+++...++.
T Consensus        55 ------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~---~~~~~~~~v~~d~~~~~~~  113 (302)
T 5OCP_A           55 ------------------QGVDAIIIAPVVETGWKPVLKEAKRAKIPVVIVDRNIKVD---DDSLFLTRIASDFSEEGRK  113 (302)
T ss_dssp             ------------------TTCSEEEECCSSSSSCHHHHHHHHHTTCCEEEESSCCCCS---CGGGCSEEEECCHHHHHHH
T ss_pred             ------------------cCCCEEEEcCCCcCChHHHHHHHHHCCCCEEEEcCCCCCC---ccccceEEEcCCchHHHHH
Confidence                              467877765443332 244556677899999887654321   1235677888888777888


Q NP_000836.2     206 MVDIVTAL--GWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET---PNARAV  278 (908)
Q Consensus       206 ~~~~l~~~--~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~---~~~~vi  278 (908)
                      +++++.+.  +.++++++..+..  ++..+.++|++.+++.+...+.......  .+..+....++++++.   .++|+|
T Consensus       114 ~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~d~i  191 (302)
T 5OCP_A          114 IGQWLMDKTQGNCDIAELQGTVGATAAIDRAAGFNQVIANYPNAKIVRSQTGE--FTRAKGKEVMEGFLKAQNGQPLCAV  191 (302)
T ss_dssp             HHHHHHHHTTTCEEEEEEECCTTCHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHHTTCCCCEE
T ss_pred             HHHHHHHHcCCCeeEEEEEcCCCCHHHHHHHHHHHHHHHhCCCcEEEEeeeCC--CCHHHHHHHHHHHHHHcCCCCccEE
Confidence            88887654  7889999985433  5667778888877764222222111111  1112333444554421   357787


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       192 ~~~~-~~~a~~~~~~l~~~g~~  212 (302)
T 5OCP_A          192 WSHN-DEMALGAVQAIKEAGLK  212 (302)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHCCCC
Confidence            7664 44566788888877764


No 170
>3BIL_A Probable LacI-family transcriptional regulator; STRUCTURAL GENOMICS, UNKNOWN FUNCTION, PSI-2; 2.5A {Corynebacterium glutamicum ATCC 13032}
Probab=97.36  E-value=2.1e-07  Score=96.38  Aligned_cols=202  Identities=11%  Similarity=0.033  Sum_probs=116.9  Template_Neff=11.400

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++.....+++.++++.+          +++.+.|+..++    +...+.++
T Consensus        63 ~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  116 (348)
T 3BIL_A           63 SSRSNTIGVIVPSLIN------------HYFAAMVTEIQSTASKAG----------LATIITNSNEDA----TTMSGSLE  116 (348)
T ss_dssp             -----CEEEEESCSSS------------HHHHHHHHHHHHHHHHTT----------CCEEEEECTTCH----HHHHHHHH
T ss_pred             cCCCCEEEEEEcCCCC------------hHHHHHHHHHHHHHHHCC----------CEEEEEcCCCCh----hhhhHHHH
Confidence            4567899999987542            255667778887777642          334455544332    22233444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   +++|++|+...+. .......+...++|+|..+...+.      .++++.+..+...
T Consensus       117 ~l~~-------------------~~~d~ii~~~~~~-~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~~~~~  170 (348)
T 3BIL_A          117 FLTS-------------------HGVDGIICVPNEE-CANQLEDLQKQGMPVVLVDRELPG------DSTIPTATSNPQP  170 (348)
T ss_dssp             HHHH-------------------TTCSCEEECCCGG-GHHHHHHHHHC-CCEEEESSCCSC------C-CCCEEEEECHH
T ss_pred             HHHH-------------------cCCCEEEECCccc-cHHHHHHHHHcCCCEEEEcCCCCC------CCCCCEEEeCcHH
Confidence            4332                   4788888755443 334445566789999987764431      2345666666666


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      .+..+++++.+.+.++++++..+.  .++..+.++|++.+++. ++.+.......  .+..+....+++++. .++|+|+
T Consensus       171 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~-~~~d~i~  246 (348)
T 3BIL_A          171 GIAAAVELLAHNNALPIGYLSGPMDTSTGRERLEDFKAACANS-KIGEQLVFLGG--YEQSVGFEGATKLLD-QGAKTLF  246 (348)
T ss_dssp             HHHHHHHHHHHTTCCSEEEECCCTTSHHHHHHHHHHHHHHHHT-TCCCCEEECCC--SSHHHHHHHHHHHHH-TTCSEEE
T ss_pred             HHHHHHHHHHhCCCCcEEEEeCCCCChhHHHHHHHHHHHHHhC-CCCcceEEecC--CChHhHHHHHHHHHh-cCCCEEE
Confidence            677777777666788999998543  35667788888888764 34332211111  112233445556653 4688877


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +.. +..+..+++++++.|..
T Consensus       247 ~~~-d~~a~~~~~~l~~~g~~  266 (348)
T 3BIL_A          247 AGD-SMMTIGVIEACHKAGLV  266 (348)
T ss_dssp             ESS-HHHHHHHHHHHHHTTCC
T ss_pred             ECC-HHHHHHHHHHHHHCCCC
Confidence            663 44566778888877763


No 171
>3O74_A Fructose transport system repressor FruR; Dual transcriptional regulator, DNA, Transcription; HET: MSE, GOL; 2.0A {Pseudomonas putida}
Probab=97.35  E-value=2.3e-07  Score=91.89  Aligned_cols=200  Identities=8%  Similarity=0.042  Sum_probs=117.4  Template_Neff=12.400

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.+        ++  +.+.+...+..    ...+..+.+.
T Consensus         2 ~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~--~~~~~~~~~~~----~~~~~~~~~~   55 (272)
T 3O74_A            2 TRTLGFILPDLEN------------PSYARIAKQLEQGARARG--------YQ--LLIASSDDQPD----SERQLQQLFR   55 (272)
T ss_dssp             CCEEEEEESCTTC------------HHHHHHHHHHHHHHHHTT--------CE--EEEEECTTCHH----HHHHHHHHHH
T ss_pred             CceEEEEeCCCCC------------hHHHHHHHHHHHHHHHcC--------cE--EEEEeCCCChh----HHHHHHHHHH
Confidence            5789999987542            255677788888877652        33  33334322211    1112222221


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   ++++++|+...+.........+...++|+|..+...+.       +.++.+..++...+.
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~-------~~~~~v~~d~~~~~~  109 (272)
T 3O74_A           56 A-------------------RRCDALFVASCLPPEDDSYRELQDKGLPVIAIDRRLDP-------AHFCSVISDDRDASR  109 (272)
T ss_dssp             H-------------------TTCSEEEECCCCCSSCCHHHHHHHTTCCEEEESSCCCT-------TTCEEEEECHHHHHH
T ss_pred             H-------------------cCCCEEEEecCCCCchHHHHHHHHCCCCEEEECCCCCC-------CCCcEEEeCcHHHHH
Confidence            1                   47888887654433334455667789999987764331       345667777777777


Q NP_000836.2     205 AMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET--PNARAVIM  280 (908)
Q Consensus       205 ~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--~~~~viv~  280 (908)
                      .+++++.+.+.++++++..+..  ++..+.++|++.+++. ++.+.......  .+..+....++++++.  .++|++++
T Consensus       110 ~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~d~v~~  186 (272)
T 3O74_A          110 QLAASLLSSAPRSIALIGARPELSVSQARAGGFDEALQGY-TGEVRRYQGEA--FSRECGQRLMQQLIDDLGGLPDALVT  186 (272)
T ss_dssp             HHHHHHHTTCCSEEEEEEECTTSHHHHHHHHHHHHHTTTC-CSEEEEEEESS--SSHHHHHHHHHHHHHHHTSCCSEEEE
T ss_pred             HHHHHHHHhCCCEEEEEEcCCCChHHHHHHHHHHHHHHhc-CCeeeEEeccc--CCHHHHHHHHHHHHHHhCCCCCEEEE
Confidence            8888876668889999985433  5667788888888765 34433211111  1112334445555421  35778776


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~  300 (908)
                      .. +..+..+++++++.|+.
T Consensus       187 ~~-~~~a~~~~~~l~~~g~~  205 (272)
T 3O74_A          187 TS-YVLLQGVFDTLQARPVD  205 (272)
T ss_dssp             SS-HHHHHHHHHHHHTSCGG
T ss_pred             cC-HHHHHHHHHHHHhCCCC
Confidence            64 33466777788777764


No 172
>3O74_B Fructose transport system repressor FruR; Dual transcriptional regulator, DNA, Transcription; HET: GOL; 2.0A {Pseudomonas putida}
Probab=97.35  E-value=2.3e-07  Score=91.89  Aligned_cols=200  Identities=8%  Similarity=0.042  Sum_probs=117.4  Template_Neff=12.400

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.+        ++  +.+.+...+..    ...+..+.+.
T Consensus         2 ~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~--~~~~~~~~~~~----~~~~~~~~~~   55 (272)
T 3O74_B            2 TRTLGFILPDLEN------------PSYARIAKQLEQGARARG--------YQ--LLIASSDDQPD----SERQLQQLFR   55 (272)
T ss_dssp             CSEEEEEESCTTC------------HHHHHHHHHHHHHHHHTT--------CE--EEEEECTTCHH----HHHHHHHHHH
T ss_pred             CceEEEEeCCCCC------------hHHHHHHHHHHHHHHHcC--------cE--EEEEeCCCChh----HHHHHHHHHH
Confidence            5789999987542            255677788888877652        33  33334322211    1112222221


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   ++++++|+...+.........+...++|+|..+...+.       +.++.+..++...+.
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~-------~~~~~v~~d~~~~~~  109 (272)
T 3O74_B           56 A-------------------RRCDALFVASCLPPEDDSYRELQDKGLPVIAIDRRLDP-------AHFCSVISDDRDASR  109 (272)
T ss_dssp             H-------------------TTCSEEEECCCSCTTCCHHHHHHHTTCCEEEESSCCCT-------TTCEEEEECHHHHHH
T ss_pred             H-------------------cCCCEEEEecCCCCchHHHHHHHHCCCCEEEECCCCCC-------CCCcEEEeCcHHHHH
Confidence            1                   47888887654433334455667789999987764331       345667777777777


Q NP_000836.2     205 AMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET--PNARAVIM  280 (908)
Q Consensus       205 ~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--~~~~viv~  280 (908)
                      .+++++.+.+.++++++..+..  ++..+.++|++.+++. ++.+.......  .+..+....++++++.  .++|++++
T Consensus       110 ~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~d~v~~  186 (272)
T 3O74_B          110 QLAASLLSSAPRSIALIGARPELSVSQARAGGFDEALQGY-TGEVRRYQGEA--FSRECGQRLMQQLIDDLGGLPDALVT  186 (272)
T ss_dssp             HHHHHHHTTCCSEEEEEEECTTSHHHHHHHHHHHHTTTTC-CSEEEEEEESS--SSHHHHHHHHHHHHHHHTSCCSEEEE
T ss_pred             HHHHHHHHhCCCEEEEEEcCCCChHHHHHHHHHHHHHHhc-CCeeeEEeccc--CCHHHHHHHHHHHHHHhCCCCCEEEE
Confidence            8888876668889999985433  5667788888888765 34433211111  1112334445555421  35778776


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~  300 (908)
                      .. +..+..+++++++.|+.
T Consensus       187 ~~-~~~a~~~~~~l~~~g~~  205 (272)
T 3O74_B          187 TS-YVLLQGVFDTLQARPVD  205 (272)
T ss_dssp             SS-HHHHHHHHHHHHHSCTT
T ss_pred             cC-HHHHHHHHHHHHhCCCC
Confidence            64 33466777788777764


No 173
>4Z0N_A Periplasmic Solute Binding Protein; Periplasmic solute binding Protein, ENZYME; HET: GAL, SO4, EDO, MSE; 1.26A {Streptobacillus moniliformis}
Probab=97.34  E-value=2.3e-07  Score=95.62  Aligned_cols=222  Identities=13%  Similarity=0.038  Sum_probs=123.0  Template_Neff=11.400

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+.++||++.|..+.            .++..+..+++.++++.        |+++++...|+..++.    ...+.
T Consensus        26 ~~~~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~v~~~~~d~~~~~~----~~~~~   81 (337)
T 4Z0N_A           26 KKDTSKITLGVTYYKFDD------------NFLAGMRNDMIQIAKEK--------YPNIELLNNDSQNSQS----ILNDQ   81 (337)
T ss_dssp             -----CEEEEEEESCTTC------------HHHHHHHHHHHHHHHHH--------CTTEEEEEEECTTCHH----HHHHH
T ss_pred             CCCCCCeEEEEEEccCCC------------HHHHHHHHHHHHHHHHH--------CCCeEEEeCCCCCCHH----HHHHH
Confidence            345568999999986542            25567778888887775        3445666555443322    23333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+... ......+...++|+|..+...+..... ..++++++.++
T Consensus        82 i~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~~-~~~~~~~v~~d  141 (337)
T 4Z0N_A           82 IEVLIN-------------------KGVNVLVINLVDPTAGQSVIDKAKAANIPIILFNKDPGVDALN-SYDKAWYVGTT  141 (337)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSSTTCHHHHHHHHHHHTCCEEEESSCCCHHHHT-TCTTEEEEECC
T ss_pred             HHHHHH-------------------cCCCEEEEecCCccchHHHHHHHHHCCCCEEEEccCCCCcccc-ccccceEEecC
Confidence            444332                   478887765433322 244556677899999887654321110 13456677777


Q NP_000836.2     199 DSYQAQAMVDIVTA------------LGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEK  264 (908)
Q Consensus       199 ~~~~~~~~~~~l~~------------~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~  264 (908)
                      ....++.+++++.+            .+.++++++..  ++.+...+.+++++.+++. ++.+..........+..+...
T Consensus       142 ~~~~~~~~~~~l~~~~~~~~~~~~~~~g~~~v~~l~~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~~~~~~~~~~~~~~  220 (337)
T 4Z0N_A          142 PKDSGILQGQVIEKAWLANPAYDLNGDGVIQYVMLFGEPGQPDAEARTKYSIEYLNEK-GIKTEELHKDIANWDAAQAKD  220 (337)
T ss_dssp             HHHHHHHHHHHHHHHHHHCGGGCTTCSSSEEEEEEECCTTCHHHHHHHHHHHHHHHHT-TCCEEEEEEEECTTCHHHHHH
T ss_pred             chHHHHHHHHHHHHHHhcCCccccCCCCeeEEEEEECCCCCcCHHHHHHHHHHHHHhc-CCCceeecccccCCCHHHHHH
Confidence            77777777776643            35678998875  3455667778888887764 343321100100011123344


Q NP_000836.2     265 IIKRLLET---PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSD  309 (908)
Q Consensus       265 ~~~~l~~~---~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~  309 (908)
                      .++++++.   .++++|+... +..+..+++++++.|.  ++.+++.+
T Consensus       221 ~~~~~l~~~~~~~~~~i~~~~-~~~a~~~~~~~~~~g~--~v~vi~~d  265 (337)
T 4Z0N_A          221 KMDAWLSGPNANKIEVVIANN-DGMALGAVESIKAVKK--ELPVFGVD  265 (337)
T ss_dssp             HHHHHHHSTTGGGCCEEEESS-HHHHHHHHHHHHHTTC--CCCEECSB
T ss_pred             HHHHHHcCCCCCCccEEEECC-hHHHHHHHHHHHHcCC--CCCEEEec
Confidence            55555431   2356666553 4455667777777663  34444443


No 174
>4PE6_B solute binding protein; Structural Genomics, PSI-Biology, Midwest Center; HET: MSE, LTH; 1.86A {Thermobispora bispora}
Probab=97.34  E-value=2.3e-07  Score=95.76  Aligned_cols=210  Identities=10%  Similarity=-0.060  Sum_probs=116.5  Template_Neff=10.900

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++.++||++.|....            .++.....+++.++++.|..++.   +++.+...|+..++.    ...+.
T Consensus        13 ~~~~~~~~Igvv~~~~~~------------~~~~~~~~g~~~a~~~~~~~gg~---~~~~~~~~d~~~~~~----~~~~~   73 (341)
T 4PE6_B           13 QAEGDKPFIALSNGFIGN------------GWRQTMIAKFEEAAKQAQADGLI---GKYKVVNAPGNNSAT----EQVAQ   73 (341)
T ss_dssp             -----CCEEEEEESCCSS------------HHHHHHHHHHHHHHHHHHHTTSC---SEEEEEECCTTTCHH----HHHHH
T ss_pred             HHhCCCCEEEEEccccCC------------HHHHHHHHHHHHHHHHhcccCCc---ceEEEEeCCCCCCHH----HHHHH
Confidence            455678999999986322            35677889999999998865432   345555555443322    23333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAA-ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   .+++++|+.. .+.........+...++|+|..+...+.       ++.+....+
T Consensus        74 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-------~~~~~~~~~  127 (341)
T 4PE6_B           74 IKSLLL-------------------QKPDALLINPASPTALQPVIQQACDAGVKVVVFDSAIDA-------PCAYILQNS  127 (341)
T ss_dssp             HHHHHT-------------------TCCSEEEEECSSSSTTHHHHHHHHHTTCEEEEESSCCCC-------TTSEEEEEC
T ss_pred             HHHHHh-------------------cCCCEEEECCCChhhhHHHHHHHHHCCCEEEEeCCCCCC-------CCcEEeeCC
Confidence            444332                   4778777643 3322234445566789999987764331       233444444


Q NP_000836.2     199 DSYQAQAMVDIVTALG--WNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-P  273 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~--~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~  273 (908)
                      ....++.+++++.+.+  .++++++..  ++.++..+.++|++.+++..++++.......  .+..+....++++++. .
T Consensus       128 ~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~  205 (341)
T 4PE6_B          128 FVDWATYAAKPVLESIGGKGNVIVVRGVVGSQPEAEMYETTKKILAEYPQVKTVATVTGM--CDGATAQKAVLGVLPSVS  205 (341)
T ss_dssp             HHHHHHHHHHHHHHHTTTCEEEEEEECSTTSHHHHHHHHHHHHHHHTCTTEEEEEEEECT--TCHHHHHHHHHHHGGGSC
T ss_pred             HHHHHHHHHHHHHHHhCCCeeEEEEecCCCChHHHHHHHHHHHHHHhCCCceEEEEEeCC--CCHHHHHHHHHHhHhhCC
Confidence            4455667777765443  678998885  3455667788888887753124443221111  1122344455555431 2


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      ++++|++.. + . ..+++++++.|.
T Consensus       206 ~~~~i~~~~-d-~-~~~~~al~~~g~  228 (341)
T 4PE6_B          206 TVDAVIGCG-D-G-YGVAQAFATAGK  228 (341)
T ss_dssp             CCCEEECSS-C-H-HHHHHHHHHHTC
T ss_pred             CCCEEEEcC-c-H-HHHHHHHHHCCC
Confidence            355555543 2 2 567777777765


No 175
>2X7X_A SENSOR PROTEIN (E.C.2.7.13.3); TRANSFERASE, SENSOR HISTIDINE KINASE; HET: PO4, FRU; 2.64A {BACTEROIDES THETAIOTAOMICRON}
Probab=97.34  E-value=2.4e-07  Score=94.96  Aligned_cols=213  Identities=11%  Similarity=0.088  Sum_probs=118.4  Template_Neff=11.000

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .+++++||++.|.+.             .++.....+++.++.+.+       |  +++.+.|+..++.    ...+.++
T Consensus         3 ~~~~~~Ig~v~~~~~-------------~~~~~~~~g~~~~~~~~~-------g--i~l~~~~~~~~~~----~~~~~~~   56 (325)
T 2X7X_A            3 DTPHFRIGVAQCSDD-------------SWRHKMNDEILREAMFYN-------G--VSVEIRSAGDDNS----KQAEDVH   56 (325)
T ss_dssp             ---CCEEEEEESCCS-------------HHHHHHHHHHHHHHTTSS-------S--CEEEEEECTTCHH----HHHHHHH
T ss_pred             CCCCeEEEEEECCCC-------------HHHHHHHHHHHHHHHHhC-------C--eEEEEEECCCCHH----HHHHHHH
Confidence            356789999998732             244455666665443321       2  3445555543322    2223344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   ++++++|+...+... ......+...++|+|..+...+.      .++++++.+++.
T Consensus        57 ~l~~-------------------~~vd~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  111 (325)
T 2X7X_A           57 YFMD-------------------EGVDLLIISANEAAPMTPIVEEAYQKGIPVILVDRKILS------DKYTAYIGADNY  111 (325)
T ss_dssp             HHHH-------------------TTCSEEEECCSSHHHHHHHHHHHHHTTCCEEEESSCCSS------SCSSEEEEECHH
T ss_pred             HHHH-------------------cCCCEEEEcCCCCCCcHHHHHHHHHCCCCEEEECCCCCC------CCccEEEEcCHH
Confidence            3332                   478887765444332 23445566789999987654321      245677888877


Q NP_000836.2     201 YQAQAMVDIVTA--LGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNA  275 (908)
Q Consensus       201 ~~~~~~~~~l~~--~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~  275 (908)
                      ..++.+++++.+  .+.++++++....  .++..+.+++++.+++.+++++.......  .+..+....+++++. ..++
T Consensus       112 ~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~  189 (325)
T 2X7X_A          112 EIGRSVGNYIASSLKGKGNIVELTGLSGSTPAMERHQGFMAAISKFPDIKLIDKADAA--WERGPAEIEMDSMLRRHPKI  189 (325)
T ss_dssp             HHHHHHHHHHHHHTTTEEEEEEEESCTTSHHHHHHHHHHHHHHHTCTEEEEEEEEECT--TSHHHHHHHHHHHHHHCSCC
T ss_pred             HHHHHHHHHHHHHcCCCeEEEEEEcCCCChHHHHHHHHHHHHHhcCCCcEEEEEeeCC--CCccHHHHHHHHHHHhCCCC
Confidence            778888888765  5778999998533  35566777888777654223332211111  111233344455542 1256


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|++.. +..+..+++++++.|+..++.+++.
T Consensus       190 ~~i~~~~-~~~a~~~~~al~~~g~~~~v~ii~~  221 (325)
T 2X7X_A          190 DAVYAHN-DRIAPGAYQAAKMAGREKEMIFVGI  221 (325)
T ss_dssp             CEEEESS-TTHHHHHHHHHHHTTCTTSSEEEEE
T ss_pred             CEEEECC-hhHHHHHHHHHHHcCCCCCCEEEEE
Confidence            7776654 3456677788887776323444443


No 176
>2X7X_B SENSOR PROTEIN (E.C.2.7.13.3); TRANSFERASE, SENSOR HISTIDINE KINASE; HET: FRU, PO4; 2.64A {BACTEROIDES THETAIOTAOMICRON}
Probab=97.34  E-value=2.4e-07  Score=94.96  Aligned_cols=213  Identities=11%  Similarity=0.088  Sum_probs=118.4  Template_Neff=11.000

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .+++++||++.|.+.             .++.....+++.++.+.+       |  +++.+.|+..++.    ...+.++
T Consensus         3 ~~~~~~Ig~v~~~~~-------------~~~~~~~~g~~~~~~~~~-------g--i~l~~~~~~~~~~----~~~~~~~   56 (325)
T 2X7X_B            3 DTPHFRIGVAQCSDD-------------SWRHKMNDEILREAMFYN-------G--VSVEIRSAGDDNS----KQAEDVH   56 (325)
T ss_dssp             ---CEEEEEEESCCS-------------HHHHHHHHHHHHHHTTST-------T--EEEEEEECTTCHH----HHHHHHH
T ss_pred             CCCCeEEEEEECCCC-------------HHHHHHHHHHHHHHHHhC-------C--eEEEEEECCCCHH----HHHHHHH
Confidence            356789999998732             244455666665443321       2  3445555543322    2223344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   ++++++|+...+... ......+...++|+|..+...+.      .++++++.+++.
T Consensus        57 ~l~~-------------------~~vd~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  111 (325)
T 2X7X_B           57 YFMD-------------------EGVDLLIISANEAAPMTPIVEEAYQKGIPVILVDRKILS------DKYTAYIGADNY  111 (325)
T ss_dssp             HHHH-------------------TTCSEEEECCSSHHHHHHHHHHHHHTTCCEEEESSCCSS------SCSSEEEEECHH
T ss_pred             HHHH-------------------cCCCEEEEcCCCCCCcHHHHHHHHHCCCCEEEECCCCCC------CCccEEEEcCHH
Confidence            3332                   478887765444332 23445566789999987654321      245677888877


Q NP_000836.2     201 YQAQAMVDIVTA--LGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNA  275 (908)
Q Consensus       201 ~~~~~~~~~l~~--~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~  275 (908)
                      ..++.+++++.+  .+.++++++....  .++..+.+++++.+++.+++++.......  .+..+....+++++. ..++
T Consensus       112 ~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~  189 (325)
T 2X7X_B          112 EIGRSVGNYIASSLKGKGNIVELTGLSGSTPAMERHQGFMAAISKFPDIKLIDKADAA--WERGPAEIEMDSMLRRHPKI  189 (325)
T ss_dssp             HHHHHHHHHHHHHTTTCEEEEEEESCTTSHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TSHHHHHHHHHHHHHHCSCC
T ss_pred             HHHHHHHHHHHHHcCCCeEEEEEEcCCCChHHHHHHHHHHHHHhcCCCcEEEEEeeCC--CCccHHHHHHHHHHHhCCCC
Confidence            778888888765  5778999998533  35566777888777654223332211111  111233344455542 1256


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|++.. +..+..+++++++.|+..++.+++.
T Consensus       190 ~~i~~~~-~~~a~~~~~al~~~g~~~~v~ii~~  221 (325)
T 2X7X_B          190 DAVYAHN-DRIAPGAYQAAKMAGREKEMIFVGI  221 (325)
T ss_dssp             CEEEESS-TTHHHHHHHHHHHTTCGGGSEEEEE
T ss_pred             CEEEECC-hhHHHHHHHHHHHcCCCCCCEEEEE
Confidence            7776654 3456677788887776323444443


No 177
>4RXM_A Possible sugar ABC superfamily ATP; TRANSPORTER, ABC-TYPE, ENZYME FUNCTION INITIATIVE; HET: BGC, INS; 1.75A {Mannheimia haemolytica}
Probab=97.33  E-value=2.4e-07  Score=92.94  Aligned_cols=205  Identities=12%  Similarity=0.043  Sum_probs=117.4  Template_Neff=12.100

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||++.|..+.            .++.....+++.++++.+          +++.+.|...++.    ...+.+++
T Consensus         2 ~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~a~~~~~----------~~~~~~~~~~~~~----~~~~~~~~   55 (292)
T 4RXM_A            2 MKDELVVFSLPNLSS------------PFEVQLQKVAVETSKKLE----------IKLQVLDGQSSST----KQASDLEN   55 (292)
T ss_dssp             CCCCEEEEEESCSSS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCHH----HHHHHHHH
T ss_pred             CcccEEEEecCCCCC------------HHHHHHHHHHHHHHHHcC----------CEEEEEcCCCCHH----HHHHHHHH
Confidence            357899999997542            255677788888877642          3445555543322    22233343


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   ++++++|+...+... ......+...++|+|..+...+.      .++++++.+++..
T Consensus        56 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~d~~~  110 (292)
T 4RXM_A           56 AIT-------------------RGAKGIIISPNDVNAISGAVEEIIKEKIPAATLDRKVES------SKPVPHFGANNYT  110 (292)
T ss_dssp             HHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCCC------SSCCCEEEECHHH
T ss_pred             HHh-------------------cCCCEEEEecCCHhhHHHHHHHHHHCCCCEEEeCCCCCC------CCCccEEecCchH
Confidence            332                   477877764433322 24445566789999987764321      2356677777777


Q NP_000836.2     202 QAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE--TPNA  275 (908)
Q Consensus       202 ~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~--~~~~  275 (908)
                      .++.+++++.+.  +.++++++..  +..++..+.+++++.+++. +..+........+.+..+....+.++++  ..++
T Consensus       111 ~~~~~~~~l~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  189 (292)
T 4RXM_A          111 GGQEVAKAVKAKYPNGAKIILLTGQPGSTSNIERTKGIRDELAAG-GDKYKIVVDQTGNWLRSEGLRIIESVLPTLKEKP  189 (292)
T ss_dssp             HHHHHHHHHHHHSTTCEEEEEEECCTTCHHHHHHHHHHHHHHHHH-CTTEEEEEEEECTTCHHHHHHHHHHHGGGCSSCC
T ss_pred             HHHHHHHHHHHHCCCCCeEEEEECCCCChhHHHHHHHHHHHHHhC-CCceEEEEeecCCCCHHHHHHHHHHHHHHcCCCC
Confidence            788888887543  5668888775  3445667788888888764 3332211111100111122233334331  1357


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |+|++.. +..+..+++++++.|..
T Consensus       190 d~i~~~~-~~~a~~~~~~~~~~g~~  213 (292)
T 4RXM_A          190 EVIISAN-DDMALGAIEALRSQGLK  213 (292)
T ss_dssp             SEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CEEEECC-hHHHHHHHHHHHHCCCC
Confidence            8865543 44566778888877763


No 178
>2HSG_A Glucose-resistance amylase regulator; CCPA, TRANSCRIPTIONAL REGULATOR, TRANSCRIPTION REGULATOR; 2.5A {Bacillus megaterium} SCOP: a.35.1.5, c.93.1.1
Probab=97.33  E-value=2.5e-07  Score=95.08  Aligned_cols=204  Identities=11%  Similarity=0.117  Sum_probs=120.7  Template_Neff=11.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++..+..+++.++++.+          +++.+.|...++    ....+.++
T Consensus        57 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  110 (332)
T 2HSG_A           57 SKKTTTVGVIIPDISN------------IFYAELARGIEDIATMYK----------YNIILSNSDQNQ----DKELHLLN  110 (332)
T ss_pred             cCCCCEEEEEeCCCCC------------hHHHHHHHHHHHHHHHhC----------CEEEEEeCCCCH----HHHHHHHH
Confidence            4568899999987542            245667778888777642          233444543332    12233444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   +++|++|+...+. .......+...++|+|.++...+       .+..+.+.+++..
T Consensus       111 ~l~~-------------------~~~d~ii~~~~~~-~~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~~~~~  163 (332)
T 2HSG_A          111 NMLG-------------------KQVDGIIFMSGNV-TEEHVEELKKSPVPVVLAASIES-------TNQIPSVTIDYEQ  163 (332)
T ss_pred             HHHH-------------------cCCCEEEECCCCC-CHHHHHHHHHcCCCEEEeCCCCC-------CCCCcEEEEChHH
Confidence            4332                   4788888754443 23444556678999998765322       2345566677767


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      .+..+++++.+.+.++++++..+..   ++..+.++|++.+++. ++.+.....+..+.+..+....+++++. ..++|+
T Consensus       164 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~  242 (332)
T 2HSG_A          164 AAFDAVQSLIDSGHKNIAFVSGTLEEPINHAKKVKGYKRALTES-GLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPTA  242 (332)
T ss_pred             HHHHHHHHHHHCCCCcEEEEeCCcccChhHHHHHHHHHHHHHHC-CCCCCHHHcccCCCCHHHHHHHHHHHHHcCCCCCE
Confidence            7777888876668889999985433   4567788888888764 3443321111110112233444555542 136788


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       243 i~~~~-~~~a~~~~~~l~~~g~~  264 (332)
T 2HSG_A          243 IFVGT-DEMALGVIHGAQDRGLN  264 (332)
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            87664 44566778888887763


No 179
>1ZHH_A Autoinducer 2-binding periplasmic protein luxP; PERIPLASMIC BINDING PROTEIN, PER/ARNT/SIMPLE-MINDED (PAS); HET: NHE; 1.94A {Vibrio harveyi} SCOP: c.93.1.1
Probab=97.33  E-value=2.5e-07  Score=95.67  Aligned_cols=220  Identities=11%  Similarity=0.031  Sum_probs=124.3  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGV--RILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~--~~~d~~~~~~~a~~~~~~~  119 (908)
                      ..+.++||++.|..+..           .+......+++.++++.+        +++++  .+.|+..++.    ...+.
T Consensus        42 ~~~~~~Ig~i~~~~~~~-----------~~~~~~~~g~~~~~~~~g--------~~~~l~~~~~d~~~~~~----~~~~~   98 (344)
T 1ZHH_A           42 TQRPIKISVVYPGQQVS-----------DYWVRNIASFEKRLYKLN--------INYQLNQVFTRPNADIK----QQSLS   98 (344)
T ss_dssp             CSSCEEEEEEEESSCSS-----------CHHHHHHHHHHHHHHHTT--------CCEEEEEEEECTTSCHH----HHHHH
T ss_pred             CCCCeEEEEEeCCCCCC-----------HHHHHHHHHHHHHHHHcC--------CcEEEEEeecCCCCCHH----HHHHH
Confidence            56789999999975321           233467788888888764        23333  4455444422    23333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRL-FKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~-~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+.........+.. .++|+|..+...+.... ...++++++.++
T Consensus        99 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~-~~~~~~~~v~~d  158 (344)
T 1ZHH_A           99 LMEALK-------------------SKSDYLIFTLDTTRHRKFVEHVLDSTNTKLILQNITTPVREW-DKHQPFLYVGFD  158 (344)
T ss_dssp             THHHHH-------------------TTCSEEEECSCTTTTHHHHHHHHHHCSSEEEEESCCSCBGGG-TTSCCSEEEECC
T ss_pred             HHHHHh-------------------cCCCEEEEeCCchHhHHHHHHHHHhCCCeEEEEeCCCCchhh-ccCCCeEEEEec
Confidence            444332                   478888876543333333444444 79999987654432111 113567777788


Q NP_000836.2     199 DSYQAQAMVDIVTALGWN--YVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PN  274 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~~~~--~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~  274 (908)
                      +...++.+++++.+.+.+  +++++..+ +.++..+.++|++.+++.+++.+.......  .+..+....++++++. .+
T Consensus       159 ~~~~~~~~~~~l~~~~~~~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~  236 (344)
T 1ZHH_A          159 HAEGSRELATEFGKFFPKHTYYSVLYFSEGYISDVRGDTFIHQVNRDNNFELQSAYYTK--ATKQSGYDAAKASLAKHPD  236 (344)
T ss_dssp             HHHHHHHHHHHHHHHSCTTCEEEEECCSTTHHCCCCCCHHHHHHHHHHCCEEEEEECCC--SSHHHHHHHHHHHHHHCCC
T ss_pred             cHHHHHHHHHHHHHhCCCCceEEEEEcCCCchHHHHHHHHHHHHHhCCCcEEEEeeecC--CCHHHHHHHHHHHHHHCCC
Confidence            777788888887654443  48888754 456667778888877754224433211111  1222344555555431 23


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +++|+.. ++..+..+++++++.|. .++.+++.
T Consensus       237 ~~~i~~~-~~~~a~~~~~~l~~~g~-~~~~v~~~  268 (344)
T 1ZHH_A          237 VDFIYAC-STDVALGAVDALAELGR-EDIMINGW  268 (344)
T ss_dssp             CSEEEES-SHHHHHHHHHHHHHHTC-TTSEEBCS
T ss_pred             ccEEEEC-ChHHHHHHHHHHHHcCC-CCcEEEEe
Confidence            4555544 34455668888888776 23344443


No 180
>5ULB_A Putative sugar ABC transporter; ABC transporter, Methylthioribose-binding protein, Structural; HET: MSE, 8GG, 8GA; 1.28A {Yersinia enterocolitica subsp. enterocolitica 8081}
Probab=97.32  E-value=2.6e-07  Score=95.13  Aligned_cols=217  Identities=12%  Similarity=0.087  Sum_probs=123.7  Template_Neff=11.700

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ......+.++||++.|..+.            .++..+..+++.++++.|          +++.+.|+..+.    +...
T Consensus        12 ~~~~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~----~~~~   65 (337)
T 5ULB_A           12 AIAKHQGQIKIAVIRNLGSD------------DNTTQFLSGVLKEGKKLG----------FKVDTFLSNGDD----ARFQ   65 (337)
T ss_dssp             HHHTCSSCCEEEEEESSCSC------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCH----HHHH
T ss_pred             HHHhccCCcEEEEEEeCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEeCCCCH----HHHH
Confidence            34566788999999997653            245677788888887753          334445544332    1223


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAA-SSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~-s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +.+++++.                   .+++++|+... +.........+...++|+|..+...+.     ..++++++.
T Consensus        66 ~~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~~~  121 (337)
T 5ULB_A           66 DFVNQAIS-------------------QKYDGIILSQGRDPYSTELVKRIVANGIAVSVFDTAIQG-----DIPGLTVTQ  121 (337)
T ss_dssp             HHHHHHHH-------------------TTCSEEEEESCCTTTHHHHHHHHHHTTCEEEEESCCCCS-----CCTTCEEEE
T ss_pred             HHHHHHHh-------------------CCCCEEEEcCCCCccCHHHHHHHHHCCCeEEEEccCCCC-----CCCCeEEEe
Confidence            33444332                   47888776543 222234445566789999987654331     124556666


Q NP_000836.2     197 PPDSYQAQAMVDIVTA--LGWNYVSTLA-SEGNYGESGVEAFTQISREIGGVCIAQSQK--IPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~--~~~~~v~ii~-~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~--~~~~~~~~~~~~~~~~l~~  271 (908)
                      +++...+..+++++.+  .+.++++++. .+..++..+.++|++.+++.+++.+.....  +.  ....+....+++++.
T Consensus       122 ~~~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~  199 (337)
T 5ULB_A          122 QDDASLTNESFGQLVKDFNGKANIIKLWVAGFPPMERRQAAYQALLKQNPGITELESIGAVSS--DVQGDTANKVGAVLA  199 (337)
T ss_dssp             ECHHHHHHHHHHHHHHHTTTCEEEEEECCTTSHHHHHHHHHHHHHHHHCTTEEEEEEECCCCT--THHHHHHHHHHHHHH
T ss_pred             cCchHHHHHHHHHHHHhhCCCccEEEEEcCCChhHHHHHHHHHHHHHhCCCcEEEEEEccCCC--CCCcchHHHHHHHHH
Confidence            6666566666666544  4678899884 334556677788888777642244332111  11  111123344555542


Q NP_000836.2     272 T-P--NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       272 ~-~--~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      . .  ++++|++.. +..+..+++++++.|+. ++.+++.
T Consensus       200 ~~~~~~~~~i~~~~-~~~a~~~~~al~~~g~~-~i~v~~~  237 (337)
T 5ULB_A          200 KYPKGKIDAIWGTW-DAFTQGAYKALQENGRT-EIKLYSI  237 (337)
T ss_dssp             HSCTTSCCEEEESS-HHHHHHHHHHHHHTTCT-TSEEEEE
T ss_pred             hCCCCCeeEEEECC-chHHHHHHHHHHHcCCC-CCEEEEE
Confidence            1 1  347776664 44466788888887762 3444443


No 181
>2FEP_A Catabolite control protein A, Phosphocarrier; CcpA, HPr, transcriptional regulator, TRANSCRIPTION; HET: SO4; 2.45A {Bacillus subtilis}
Probab=97.32  E-value=2.7e-07  Score=92.60  Aligned_cols=206  Identities=9%  Similarity=0.056  Sum_probs=118.1  Template_Neff=11.700

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+..+||++.|..+.            .++.....+++.++++.+        +++  .+.+...++    ....+.
T Consensus        11 ~~~~~~~~igvi~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~--~~~~~~~~~----~~~~~~   64 (289)
T 2FEP_A           11 GSSKKTTTVGVIIPDISS------------IFYSELARGIEDIATMYK--------YNI--ILSNSDQNM----EKELHL   64 (289)
T ss_dssp             -----CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------CEE--EEEECTTCH----HHHHHH
T ss_pred             CCCCCccEEEEEeCCCCc------------HHHHHHHHHHHHHHHHcC--------CcE--EEEeCCCCH----HHHHHH
Confidence            345678899999987542            255677788887777642        333  334433332    222333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++++.                   ++++++|+...+.. ......+...++|+|..+...+       .+..+.+..++
T Consensus        65 ~~~l~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~  117 (289)
T 2FEP_A           65 LNTMLG-------------------KQVDGIVFMGGNIT-DEHVAEFKRSPVPIVLAASVEE-------QEETPSVAIDY  117 (289)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSCCC-HHHHHHHHHSSSCEEEESCCCT-------TCCSCEEECCH
T ss_pred             HHHHhc-------------------CCCCEEEEeCCCCC-HHHHHHHHhCCCCEEEEcCCCC-------CCCCCEEEeCH
Confidence            443332                   47888887554433 3444556678999998765432       13455666777


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGNYG---ESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNA  275 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~~~---~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~  275 (908)
                      ...++.+++++.+.+.++++++..+..++   ..+.+++++.+++. ++.+........+.+..+....++++++ ..++
T Consensus       118 ~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  196 (289)
T 2FEP_A          118 EQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEA-NLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKP  196 (289)
T ss_dssp             HHHHHHHHHHHHHTTCSSEEEEESCTTSHCCCCCCHHHHHHHHHHT-TCCCCGGGEEECCSCHHHHHHHHHHHTTSSSCC
T ss_pred             HHHHHHHHHHHHHCCCCcEEEEeCCCCCCccHHHHHHHHHHHHHHC-CCCCCHHHhccCCCCcchHHHHHHHHHhcCCCC
Confidence            77777888887666888999998654433   56677888877764 2332211111100111233344555542 1367


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |+|++.. +..+..+++++++.|+.
T Consensus       197 d~i~~~~-~~~~~~~~~~l~~~g~~  220 (289)
T 2FEP_A          197 TAILSAT-DEMALGIIHAAQDQGLS  220 (289)
T ss_dssp             SEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CEEEECC-cHHHHHHHHHHHHCCCC
Confidence            8887664 44567778888877764


No 182
>2IKS_A DNA-binding transcriptional dual regulator; DNA-binding transcriptional dual regulator, Escherichia; 1.85A {Escherichia coli}
Probab=97.31  E-value=2.7e-07  Score=92.64  Aligned_cols=204  Identities=11%  Similarity=0.090  Sum_probs=117.9  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...+.++||++.|..+.            .++.....+++.++++.+          +++.+.+...+.    +...+.+
T Consensus        16 ~~~~~~~Ig~~~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~   69 (293)
T 2IKS_A           16 RAGRTRSIGLVIPDLEN------------TSYTRIANYLERQARQRG----------YQLLIACSEDQP----DNEMRCI   69 (293)
T ss_dssp             --CCCCEEEEEESCSCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHH
T ss_pred             hcCCCCEEEEEecCCCC------------hHHHHHHHHHHHHHHHcC----------CeEEEEeCCCCH----HHHHHHH
Confidence            44578999999987542            245667778887777642          233344443332    2223334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   ++++++|+...+.........+...++|+|..+...+.       +..+.+..++.
T Consensus        70 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~-------~~~~~~~~~~~  123 (293)
T 2IKS_A           70 EHLLQ-------------------RQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDR-------EHFTSVVGADQ  123 (293)
T ss_dssp             HHHHH-------------------TTCSEEEECCSSCTTCHHHHTTTTSSSCEEEEESCCCT-------TTCEEEEECHH
T ss_pred             HHHHh-------------------CCCCEEEECCCCCCCchHHHHHHcCCCCEEEEcCCcCc-------ccCcEEEeCcH
Confidence            43332                   47888887554433333445566789999987764331       23455666666


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ..+..+++++.+.+.++++++..  +..+...+.++|++.+++. ++.+.......  .+..+....++++++. .++|+
T Consensus       124 ~~~~~~~~~l~~~g~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~d~  200 (293)
T 2IKS_A          124 DDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDD-PREVHFLYANS--YEREAAAQLFEKWLETHPMPQA  200 (293)
T ss_dssp             HHHHHHHHHHHTSCCSSEEEEEECTTSHHHHHHHHHHHHHHTTC-CCCEEEEEESS--SCHHHHHHHHHHHTTTSCCCSE
T ss_pred             HHHHHHHHHHHhCCCcEEEEEeCCccchhHHHHHHHHHHHHHhC-CCceeeeecCC--CCHHHHHHHHHHHHHhCCCCCE
Confidence            66777788776667889999985  3345666778888887764 34433211111  1112233445555421 24777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++.+.|..
T Consensus       201 i~~~~-~~~a~~~~~~~~~~~~~  222 (293)
T 2IKS_A          201 LFTTS-FALLQGVMDVTLRRDGK  222 (293)
T ss_dssp             EEESS-HHHHHHHHHHHHHHHSS
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            77654 44456677777776653


No 183
>3D8U_A PurR transcriptional regulator; APC91343.1, PurR, transcriptional regulator, Vibrio; HET: MSE; 2.88A {Vibrio parahaemolyticus}
Probab=97.31  E-value=2.7e-07  Score=91.46  Aligned_cols=202  Identities=12%  Similarity=0.082  Sum_probs=116.7  Template_Neff=12.400

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ++++||++.|....            .++..+..+++.++++.+          +++.+.++..++    +...+.++++
T Consensus         2 ~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~~~   55 (275)
T 3D8U_A            2 NAYSIALIIPSLFE------------KACAHFLPSFQQALNKAG----------YQLLLGYSDYSI----EQEEKLLSTF   55 (275)
T ss_dssp             --CEEEEEESCSSC------------HHHHHHHHHHHHHHHHTS----------CEECCEECTTCH----HHHHHHHHHH
T ss_pred             CcceEEEEeCccCC------------hhHHHHHHHHHHHHHHcC----------CEEEEEeCCCCH----HHHHHHHHHH
Confidence            46889999987532            245667778887777642          233444443332    1223334433


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      +.                   .+++++|+...+... .....+...++|+|..+...+       .++.+.+..+....+
T Consensus        56 ~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~~~~  108 (275)
T 3D8U_A           56 LE-------------------SRPAGVVLFGSEHSQ-RTHQLLEASNTPVLEIAELSS-------KASYLNIGVDHFEVG  108 (275)
T ss_dssp             HT-------------------SCCCCEEEESSCCCH-HHHHHHHHHTCCEEEESSSCS-------SSSSEEECBCHHHHH
T ss_pred             HH-------------------hCCCEEEEeCCCCCH-HHHHHHHhCCCCEEEEcCCCC-------CCCCcEEEeCHHHHH
Confidence            32                   478888875544333 344556678999988765432       134566677777777


Q NP_000836.2     204 QAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAVIM  280 (908)
Q Consensus       204 ~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~viv~  280 (908)
                      +.+++++.+.+.++++++..+..  .+..+.++|++.+++. ++.+..........+..+....++++++ ..++|+|++
T Consensus       109 ~~~~~~l~~~g~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~d~i~~  187 (275)
T 3D8U_A          109 KACTRHLIEQGFKNVGFIGARGNHSTLQRQLHGWQSAMIEN-YLTPDHFLTTHEAPSSQLGAEGLAKLLLRDSSLNALVC  187 (275)
T ss_dssp             HHHHHHHHTTTCCCEEEEECSCSSHHHHHHHHHHHHHHHHT-TCCCCCEEECSSCCCHHHHHHHHHHHHTTCTTCCEEEE
T ss_pred             HHHHHHHHHCCCCcEEEEecCCCchHHHHHHHHHHHHHHHC-CCCcceEEecCCCCchhhHHHHHHHHHhcCCCCCEEEE
Confidence            78888876668889999985443  4556777888877764 3433211111100111223344555542 134788876


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~  300 (908)
                      .. +..+..+++++++.|+.
T Consensus       188 ~~-~~~~~~~~~~~~~~g~~  206 (275)
T 3D8U_A          188 SH-EEIAIGALFECHRRVLK  206 (275)
T ss_dssp             SS-HHHHHHHHHHHHHTTCC
T ss_pred             CC-HHHHHHHHHHHHHCCCC
Confidence            64 35566778888877763


No 184
>3D8U_B PurR transcriptional regulator; APC91343.1, PurR, transcriptional regulator, Vibrio; 2.88A {Vibrio parahaemolyticus}
Probab=97.31  E-value=2.7e-07  Score=91.46  Aligned_cols=202  Identities=12%  Similarity=0.082  Sum_probs=116.7  Template_Neff=12.400

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ++++||++.|....            .++..+..+++.++++.+          +++.+.++..++    +...+.++++
T Consensus         2 ~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~~~   55 (275)
T 3D8U_B            2 NAYSIALIIPSLFE------------KACAHFLPSFQQALNKAG----------YQLLLGYSDYSI----EQEEKLLSTF   55 (275)
T ss_dssp             --CCEEEEESCSSC------------HHHHHHHHHHHHHHHHHT----------CCEEEEECSSCH----HHHHHHHHHH
T ss_pred             CcceEEEEeCccCC------------hhHHHHHHHHHHHHHHcC----------CEEEEEeCCCCH----HHHHHHHHHH
Confidence            46889999987532            245667778887777642          233444443332    1223334433


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      +.                   .+++++|+...+... .....+...++|+|..+...+       .++.+.+..+....+
T Consensus        56 ~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~~~~  108 (275)
T 3D8U_B           56 LE-------------------SRPAGVVLFGSEHSQ-RTHQLLEASNTPVLEIAELSS-------KASYLNIGVDHFEVG  108 (275)
T ss_dssp             HT-------------------TCCSCEEEESSCCCH-HHHHHHHHTTCCEEEESSSCS-------SSSCEEECCCHHHHH
T ss_pred             HH-------------------hCCCEEEEeCCCCCH-HHHHHHHhCCCCEEEEcCCCC-------CCCCcEEEeCHHHHH
Confidence            32                   478888875544333 344556678999988765432       134566677777777


Q NP_000836.2     204 QAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAVIM  280 (908)
Q Consensus       204 ~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~viv~  280 (908)
                      +.+++++.+.+.++++++..+..  .+..+.++|++.+++. ++.+..........+..+....++++++ ..++|+|++
T Consensus       109 ~~~~~~l~~~g~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~d~i~~  187 (275)
T 3D8U_B          109 KACTRHLIEQGFKNVGFIGARGNHSTLQRQLHGWQSAMIEN-YLTPDHFLTTHEAPSSQLGAEGLAKLLLRDSSLNALVC  187 (275)
T ss_dssp             HHHHHHHHHTTCCCEEEEEECTTSHHHHHHHHHHHHHHHHT-TCCCCCEEEESSCCCHHHHHHHHHHHHHHCTTCCEEEE
T ss_pred             HHHHHHHHHCCCCcEEEEecCCCchHHHHHHHHHHHHHHHC-CCCcceEEecCCCCchhhHHHHHHHHHhcCCCCCEEEE
Confidence            78888876668889999985443  4556777888877764 3433211111100111223344555542 134788876


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~~  300 (908)
                      .. +..+..+++++++.|+.
T Consensus       188 ~~-~~~~~~~~~~~~~~g~~  206 (275)
T 3D8U_B          188 SH-EEIAIGALFECHRRVLK  206 (275)
T ss_dssp             SS-HHHHHHHHHHHHHHTCC
T ss_pred             CC-HHHHHHHHHHHHHCCCC
Confidence            64 35566778888877763


No 185
>1JHZ_B PURINE NUCLEOTIDE SYNTHESIS REPRESSOR; corepressor binding domain, purine repressor; 2.4A {Escherichia coli} SCOP: c.93.1.1
Probab=97.31  E-value=2.7e-07  Score=92.37  Aligned_cols=206  Identities=14%  Similarity=0.127  Sum_probs=112.9  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++..+||++.|..+.            .++..+..+++.++++.|          +++.+.++..++    +...+.+
T Consensus         3 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~   56 (289)
T 1JHZ_B            3 KVNHTKSIGLLATSSEA------------AYFAEIIEAVEKNCFQKG----------YTLILGNAWNNL----EKQRAYL   56 (289)
T ss_dssp             -----CEEEEEESCSSC------------HHHHHHHHHHHHHHHHTT----------CEEEEEECCSCH----HHHHHHH
T ss_pred             ccCCcceEEEEeCCCCC------------hhHHHHHHHHHHHHHHhC----------CeEEEEecCCCH----HHHHHHH
Confidence            34567899999987542            245667778887777643          233444443332    2223334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILR-LFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~-~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++..                   .++|++|+...+... .....+. ..++|+|..+...+.      .++.+.+..++
T Consensus        57 ~~~~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~~~  110 (289)
T 1JHZ_B           57 SMMAQ-------------------KRVDGLLVMCSEYPE-PLLAMLEEYRHIPMVVMDFGEAK------ADFTDAVIDNA  110 (289)
T ss_dssp             HHHHH-------------------TTCSCCCEECSCCCH-HHHHHHHHTTTSCCCEEEESSCC------TTSCCEEECCH
T ss_pred             HHHHh-------------------cCCCEEEEecCCCCH-HHHHHHHHhCCCCEEEeeCCCcc------ccCceEEEeCh
Confidence            43332                   478888875443222 2233333 479999987654321      23445566666


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ...++.+++++.+.+.++++++..  +..++..+.++|++.+++. ++.+..........+..+....++++++. .+++
T Consensus       111 ~~~~~~~~~~l~~~~~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~  189 (289)
T 1JHZ_B          111 FEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEA-MIKVPESWIVQGDFEPESGYRAMQQILSQPHRPT  189 (289)
T ss_dssp             HHHHHHHHHHHHHTTCCSEEEECCC------CHHHHHHHHHHHHT-TCCCCGGGBCCCCSSHHHHHHHHHHHHSSSSCCS
T ss_pred             HHHHHHHHHHHHHCCCCcEEEeeCCCCccChHHHHHHHHHHHHHc-CCCCCHHHeeecCCChHHHHHHHHHHHhCCCCCc
Confidence            677778888886667889999985  3345667778888888765 34433211011001112333445555421 2467


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +|++.. +..+..+++++++.|+.
T Consensus       190 ~i~~~~-~~~~~~~~~~l~~~g~~  212 (289)
T 1JHZ_B          190 AVFCGG-DIMAMGALCAADEMGLR  212 (289)
T ss_dssp             EEEESC-HHHHHHHHHHHHHHTCC
T ss_pred             EEEECC-HHHHHHHHHHHHHCCCC
Confidence            776654 44556778888877763


No 186
>2P9H_A Lactose operon repressor; Lac repressor, allosteric effectors, gene; HET: IPT; 2.0A {Escherichia coli} SCOP: c.93.1.1
Probab=97.30  E-value=2.8e-07  Score=91.05  Aligned_cols=199  Identities=12%  Similarity=0.076  Sum_probs=116.1  Template_Neff=12.200

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIE  125 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~~  125 (908)
                      ++||++.|..+.            .++..+..+++.++++.+        +++.+...+. .++    +...+.+++++.
T Consensus         1 ~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~~~~~~~~~l~~   55 (269)
T 2P9H_A            1 LLIGVATSSLAL------------HAPSQIVAAIKSRADQLG--------ASVVVSMVER-SGV----EACKAAVHNLLA   55 (269)
T ss_dssp             CEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT--------CEEEEEECCS-SSH----HHHHHHHHHHHT
T ss_pred             CeEEEEeCcccc------------cchHHHHHHHHHHHHHcC--------CcEEEEEccC-CcH----HHHHHHHHHHHh
Confidence            478999887542            255677788888887753        3344333222 111    122233443332


Q NP_000836.2     126 KDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQA  205 (908)
Q Consensus       126 ~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~  205 (908)
                                         .+++++|+...+.........+...++|+|..+...+        ++++++.+++...++.
T Consensus        56 -------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~--------~~~~~v~~d~~~~~~~  108 (269)
T 2P9H_A           56 -------------------QRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQ--------TPINSIIFSHEDGTRL  108 (269)
T ss_dssp             -------------------TTCSEEEEESCCCHHHHHHHHHHTTTSCEEESSSCTT--------SSSCEEEECHHHHHHH
T ss_pred             -------------------CCCCEEEEeCCCCChHHHHHHHHHcCCCEEEeeCCCC--------CCCCEEEECChHHHHH
Confidence                               4788888764443322222345678999998765432        2456667777777778


Q NP_000836.2     206 MVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAVIMFA  282 (908)
Q Consensus       206 ~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~viv~~~  282 (908)
                      +++++.+.+.++++++..  ++.++..+.+++++.+++. ++++.......  .+..+....+++++.. .++|+|++..
T Consensus       109 ~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~d~i~~~~  185 (269)
T 2P9H_A          109 GVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRN-QIQPIAEREGD--WSAMSGFQQTMQMLNEGIVPTAMLVAN  185 (269)
T ss_dssp             HHHHHHHHTCCCEEEEECCTTSHHHHHHHHHHHHHHHHT-TCCCSEEEECC--SSHHHHHHHHHHHHHTTCCCSEEEESS
T ss_pred             HHHHHHHCCCCcEEEEeCCcCCHHHHHHHHHHHHHHHHC-CCCCceeecCC--CchhHHHHHHHHHHhcCCCCCEEEECC
Confidence            888876667889999885  3345667778888888775 35443221111  1112233445555421 2477776664


Q NP_000836.2     283 NEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~  300 (908)
                       +..+..+++++++.|..
T Consensus       186 -~~~~~~~~~~l~~~~~~  202 (269)
T 2P9H_A          186 -DQMALGAMRAITESGLR  202 (269)
T ss_dssp             -HHHHHHHHHHHHHTTCC
T ss_pred             -HHHHHHHHHHHHHcCCC
Confidence             34466777788777764


No 187
>2PAF_B Lactose operon repressor; Lac repressor, allosteric effectors, gene; HET: NPF; 3.5A {Escherichia coli} SCOP: c.93.1.1
Probab=97.30  E-value=2.8e-07  Score=91.05  Aligned_cols=199  Identities=12%  Similarity=0.076  Sum_probs=116.1  Template_Neff=12.200

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIE  125 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~~  125 (908)
                      ++||++.|..+.            .++..+..+++.++++.+        +++.+...+. .++    +...+.+++++.
T Consensus         1 ~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~~~~~~~~~l~~   55 (269)
T 2PAF_B            1 LLIGVATSSLAL------------HAPSQIVAAIKSRADQLG--------ASVVVSMVER-SGV----EACKAAVHNLLA   55 (269)
T ss_dssp             CEEEEEESCTTS------------HHHHHHHHHHHHHHGGGT--------CEEEEEECCS-SSH----HHHHHHHHHHHT
T ss_pred             CeEEEEeCcccc------------cchHHHHHHHHHHHHHcC--------CcEEEEEccC-CcH----HHHHHHHHHHHh
Confidence            478999887542            255677788888887753        3344333222 111    122233443332


Q NP_000836.2     126 KDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQA  205 (908)
Q Consensus       126 ~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~  205 (908)
                                         .+++++|+...+.........+...++|+|..+...+        ++++++.+++...++.
T Consensus        56 -------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~--------~~~~~v~~d~~~~~~~  108 (269)
T 2PAF_B           56 -------------------QRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQ--------TPINSIIFSHEDGTRL  108 (269)
T ss_dssp             -------------------TTCSEEEEESCCCHHHHHHHHHHTCSSCEEESSSCTT--------SCSSEEEECHHHHHHH
T ss_pred             -------------------CCCCEEEEeCCCCChHHHHHHHHHcCCCEEEeeCCCC--------CCCCEEEECChHHHHH
Confidence                               4788888764443322222345678999998765432        2456667777777778


Q NP_000836.2     206 MVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAVIMFA  282 (908)
Q Consensus       206 ~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~viv~~~  282 (908)
                      +++++.+.+.++++++..  ++.++..+.+++++.+++. ++++.......  .+..+....+++++.. .++|+|++..
T Consensus       109 ~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~d~i~~~~  185 (269)
T 2PAF_B          109 GVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRN-QIQPIAEREGD--WSAMSGFQQTMQMLNEGIVPTAMLVAN  185 (269)
T ss_dssp             HHHHHHTTTCCCEEEEECCTTSHHHHHHHHHHHHHHHTT-TCCCSCEEECC--SCHHHHHHTHHHHGGGTCCCSEEEESS
T ss_pred             HHHHHHHCCCCcEEEEeCCcCCHHHHHHHHHHHHHHHHC-CCCCceeecCC--CchhHHHHHHHHHHhcCCCCCEEEECC
Confidence            888876667889999885  3345667778888888775 35443221111  1112233445555421 2477776664


Q NP_000836.2     283 NEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       283 ~~~~~~~~l~~~~~~g~~  300 (908)
                       +..+..+++++++.|..
T Consensus       186 -~~~~~~~~~~l~~~~~~  202 (269)
T 2PAF_B          186 -DQMALGAMRAITESGLR  202 (269)
T ss_dssp             -HHHHHHHHHHHHHTTCC
T ss_pred             -HHHHHHHHHHHHHcCCC
Confidence             34466777788777764


No 188
>3K4H_A putative transcriptional regulator; STRUCTURAL GENOMICS, CRYSTAL STRUCTURE,PROTEIN STRUCTURE; HET: MAL; 2.8A {Bacillus cytotoxicus NVH 391-98}
Probab=97.30  E-value=2.9e-07  Score=92.38  Aligned_cols=210  Identities=10%  Similarity=0.048  Sum_probs=120.5  Template_Neff=11.900

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|.++....       ...++..+..+++.++++.+        +++  .+.|...+.    +...+.++
T Consensus         5 ~~~~~~Ig~v~~~~~~~~~-------~~~~~~~~~~~~~~~~~~~g--------~~~--~~~~~~~~~----~~~~~~~~   63 (292)
T 3K4H_A            5 NQTTKTLGLVMPSSASKAF-------QNPFFPEVIRGISSFAHVEG--------YAL--YMSTGETEE----EIFNGVVK   63 (292)
T ss_dssp             --CCCEEEEECSSCHHHHT-------TSTHHHHHHHHHHHHHHHTT--------CEE--EECCCCSHH----HHHHHHHH
T ss_pred             cCCCCEEEEEecCchhhhh-------cCCcHHHHHHHHHHHHHHcC--------cEE--EEECCCChH----HHHHHHHH
Confidence            4568999999998641000       01355677788888877642        233  333432221    11222222


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      .+..                   .+++++|+...+.. ......+...++|+|..+...+.      .++++++.++...
T Consensus        64 ~~~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~~  117 (292)
T 3K4H_A           64 MVQG-------------------RQIGGIILLYSREN-DRIIQYLHEQNFPFVLIGKPYDR------KDEITYVDNDNYT  117 (292)
T ss_dssp             HHHT-------------------TCCCEEEESCCBTT-CHHHHHHHHTTCCEEEESCCSSC------TTTSCEEECCHHH
T ss_pred             HHHc-------------------CCCCEEEEecccCC-hHHHHHHHHCCCCEEEeCCCCCC------CCCccEEEcCHHH
Confidence            2221                   47888887654433 34445566789999987764431      2456777788877


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .++.+++++.+.+.++++++..  +...+..+.++|++.+++. ++.+........+.+..+....++++++ ..++|+|
T Consensus       118 ~~~~~~~~l~~~g~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d~i  196 (292)
T 3K4H_A          118 AAREVAEYLISLGHKQIAFIGGGSDLLVTRDRLAGMSDALKLA-DIVLPKEYILHFDFSRESGQQAVEELMGLQQPPTAI  196 (292)
T ss_dssp             HHHHHHHHHHHTTCCCEEEEESCTTBHHHHHHHHHHHHHHHHT-TCCCCGGGEEECCSSHHHHHHHHHHHHTSSSCCSEE
T ss_pred             HHHHHHHHHHHCCCCeEEEEcCCcccHHHHHHHHHHHHHHHHc-CCCCChhheeccCCCHHHHHHHHHHHHhcCCCCCEE
Confidence            8888888887668889999985  3345566778888887764 3444321111100111233344455442 1367787


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       197 ~~~~-~~~a~~~~~~~~~~g~~  217 (292)
T 3K4H_A          197 MATD-DLIGLGVLSALSKKGFV  217 (292)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-hHHHHHHHHHHHHcCCC
Confidence            7664 44566778888877763


No 189
>4RXT_A Sugar ABC transporter; SUGAR TRANSPORTER, ABC-TYPE, ENZYME FUNCTION; HET: ARA; 1.35A {Agrobacterium radiobacter}
Probab=97.30  E-value=3e-07  Score=92.78  Aligned_cols=213  Identities=11%  Similarity=0.021  Sum_probs=120.7  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||++.|.++.            .++.....+++.++++.        |+++.+...|+..+.    +...+.+++
T Consensus         2 ~~~~~Igvi~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~~~~~~~~~~~~~----~~~~~~~~~   57 (299)
T 4RXT_A            2 MAEVTIPIIVKDTTS------------FYWQIVLAGARKAGKDL--------GVKVPELGAQAETDV----NGQISILEN   57 (299)
T ss_dssp             TTCCBCCEEESCTTS------------HHHHHHHHHHHHHHHHH--------TCBCCEEECSCTTCH----HHHHHHHHH
T ss_pred             CCCeEEEEEeccCCC------------hhHHHHHHHHHHHHHHh--------CCEEEEecCCcCCCH----HHHHHHHHH
Confidence            357899999997542            25567778888888775        344555444432222    122333443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +..                   ++++++|+...+.... .....+ ..++|++..+...+.      .++.+++.+++..
T Consensus        58 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~-~~~ipvv~~~~~~~~------~~~~~~v~~d~~~  111 (299)
T 4RXT_A           58 AVA-------------------GKPAAIVISPTEFKALGKPVDEA-AKSVPIIGIDSGADS------KAFKSFLTTDNTQ  111 (299)
T ss_dssp             HHH-------------------TCCSCEEECCSSTTTTHHHHHHH-HTTSCEEEESSCCSC------SCCSEEEECCHHH
T ss_pred             HHh-------------------CCCCEEEECCCChHhccHHHHHH-HhCCCEEEEccCCCc------ccccEEEecCHHH
Confidence            332                   4788887654443321 233334 579999987654321      2445677777777


Q NP_000836.2     202 QAQAMVDIVTA-------LGWNYVSTLAS--EGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       202 ~~~~~~~~l~~-------~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      .++.+++++.+       .+.++++++..  +..++..+.++|++.+++.+ ++++.......  .+..+....++++.+
T Consensus       112 ~~~~~~~~l~~~l~~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~  189 (299)
T 4RXT_A          112 GGRIAADGLAAAIKAMTGKEEGDVVIITNTPGAGSLEQRRTGFLDQVKTKYPGLKVVADKYAD--GQATTGLNIMTDLIT  189 (299)
T ss_dssp             HHHHHHHHHHHHHHHHHSSSCEEEEEEESSTTCHHHHHHHHHHHHHHHHHCTTEEEEEEEECC--SCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHhhCCCCceEEEEEcCCCCchHHHHHHHHHHHHHHHCCCcEEeeeecCC--CCHHHHHHHHHHHHH
Confidence            77777777654       36789999985  33456677788888776531 23332211111  111233444555542


Q NP_000836.2     272 -TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       272 -~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                       ..++++|++.. +..+..+++++++.|...++.+++.
T Consensus       190 ~~~~~~~i~~~~-~~~a~~~~~~l~~~g~~~~i~i~g~  226 (299)
T 4RXT_A          190 ANPKIVGVFASN-LIMAQGVGQAIAENKLSDKVKVIGF  226 (299)
T ss_dssp             HCTTEEEEEECS-HHHHHHHHHHHHHTTCTTTCEEEEE
T ss_pred             HCCCccEEEECC-hhhHHHHHHHHHHCCCCCCeEEEEE
Confidence             12456665553 4456678888888776323444443


No 190
>4ZJP_A solute binding protein; Solute binding protein, ENZYME FUNCTION; HET: MSE, RIP, EDO; 1.63A {Actinobacillus succinogenes (strain ATCC 55618 / 130Z)}
Probab=97.29  E-value=3e-07  Score=92.30  Aligned_cols=206  Identities=13%  Similarity=0.068  Sum_probs=115.9  Template_Neff=11.800

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      .....++.++||++.|..+.            .++.....+++.++++.|          +++.+.|+..++.    ...
T Consensus        17 ~~~~~~~~~~Ig~v~~~~~~------------~~~~~~~~~~~~~~~~~~----------~~~~~~~~~~~~~----~~~   70 (292)
T 4ZJP_A           17 NLYFQSMQETIALTVSTLDN------------PFFVSLKDGAQKKATELG----------YKLVVLDSQNDPS----KEL   70 (292)
T ss_dssp             ------CCCEEEEEESCSSS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCHH----HHH
T ss_pred             ccccccCCcEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCHH----HHH
Confidence            34566789999999997542            255677788888887753          3344455443322    222


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIG-AAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg-~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +.++++..                   ++++++|. +..+.........+...++|+|..+...+.      .++++++.
T Consensus        71 ~~~~~l~~-------------------~~~~~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~  125 (292)
T 4ZJP_A           71 SNVEDLTV-------------------RGAKVLLINPTDSAAVSNAVAIANRNKIPVITLDRGAAK------GEVVSHIA  125 (292)
T ss_dssp             HHHHHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCSS------SCCSEEEE
T ss_pred             HHHHHHHh-------------------CCCCEEEEcCCChhHHHHHHHHHHHCCCCEEEECCCCCC------CCceEEEE
Confidence            33333332                   35665554 333332224445566789999987654321      34677888


Q NP_000836.2     197 PPDSYQAQAMVDIVTAL---GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~~---~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      +++...++.+++++.+.   +.+ ++++..  ++.++..+.+++++.+++. ++.+.......  .+..+....++++++
T Consensus       126 ~d~~~~~~~~~~~l~~~~~~~~~-~~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~  201 (292)
T 4ZJP_A          126 SDNVAGGKMAGDFIAQKLGDGAK-VIQLEGLAGTSAARERGEGFKQAIEAH-KFDVLASQPAD--FDRTKGLNVTENLLA  201 (292)
T ss_dssp             ECHHHHHHHHHHHHHHHHCTTCE-EEEEECCTTSHHHHHHHHHHHHHHHHH-TCEEEEEEECT--TCHHHHHHHHHHHHH
T ss_pred             cChHHHHHHHHHHHHHHhCCCcE-EEEEECCCCCHHHHHHHHHHHHHHHhc-CCeEEEeecCC--CCHHHHHHHHHHHHH
Confidence            88888888888887543   344 555543  3456677788888888775 35443221111  112234445555542


Q NP_000836.2     272 T-PNARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       272 ~-~~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      . .++++|++.. +..+..+++++++.|.
T Consensus       202 ~~~~~~~i~~~~-~~~a~~~~~~~~~~g~  229 (292)
T 4ZJP_A          202 SKGSVQAIFAQN-DEMALGALRAISAAGK  229 (292)
T ss_dssp             HSTTCCEEEESS-HHHHHHHHHHHHHHTC
T ss_pred             hcCCCCEEEECC-hHHHHHHHHHHHHCCC
Confidence            1 2456665543 4456678888887775


No 191
>2VK2_A ABC TRANSPORTER PERIPLASMIC-BINDING PROTEIN YTFQ; TRANSPORT PROTEIN, ABC TRANSPORT, GALACTOFURANOSE; HET: GZL; 1.2A {ESCHERICHIA COLI}
Probab=97.28  E-value=3.2e-07  Score=92.93  Aligned_cols=205  Identities=11%  Similarity=0.090  Sum_probs=118.5  Template_Neff=11.600

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|.+..            .++.....+++.++++.|          +++.+.|...++    +...+.+++++
T Consensus         2 ~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~~l~   55 (306)
T 2VK2_A            2 PLTVGFSQVGSES------------GWRAAETNVAKSEAEKRG----------ITLKIADGQQKQ----ENQIKAVRSFV   55 (306)
T ss_dssp             CCEEEEEECCCCS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCH----HHHHHHHHHHH
T ss_pred             CcEEEEEecCCCC------------hHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCH----HHHHHHHHHHH
Confidence            5789999997632            245566677777777653          344455544332    22333444433


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++|....... .......+...++|+|..+...+..   ...++++++.+++...+
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~---~~~~~~~~v~~d~~~~~  113 (306)
T 2VK2_A           56 A-------------------QGVDAIFIAPVVATGWEPVLKEAKDAEIPVFLLDRSIDVK---DKSLYMTTVTADNILEG  113 (306)
T ss_dssp             H-------------------HTCSEEEECCSSSSSCHHHHHHHHHTTCCEEEESSCCCCS---CGGGSSEEEECCHHHHH
T ss_pred             H-------------------cCCCEEEEcCCCccChHHHHHHHHHCCCCEEEECCCCCCC---CccceEEEEecChHHHH
Confidence            2                   46776665433322 2244455677899999877644321   01245677778887778


Q NP_000836.2     204 QAMVDIVTALGWN---YVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET----PN  274 (908)
Q Consensus       204 ~~~~~~l~~~~~~---~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~----~~  274 (908)
                      +.+++++.+.+.+   +++++..  ++.++..+.++|++.+++.+.+++.......  .+..+....+++++..    .+
T Consensus       114 ~~~~~~l~~~~~~~~~~v~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~  191 (306)
T 2VK2_A          114 KLIGDWLVKEVNGKPCNVVELQGTVGASVAIDRKKGFAEAIKNAPNIKIIRSQSGD--FTRSKGKEVMESFIKAENNGKN  191 (306)
T ss_dssp             HHHHHHHHHHHTTSCEEEEEEECSTTCHHHHHHHHHHHHHTTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHTTTTTT
T ss_pred             HHHHHHHHHHhCCCCceEEEEEcCCCCHHHHHHHHHHHHHHHhCCCeEEEeeecCC--CCHHHHHHHHHHHHHHhcCCCC
Confidence            8888887554333   7888875  4456667788888887764213432211111  1112333445555421    35


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +++|++.. +..+..+++++++.|+.
T Consensus       192 ~d~i~~~~-~~~a~~~~~~l~~~g~~  216 (306)
T 2VK2_A          192 ICMVYAHN-DDMVIGAIQAIKEAGLK  216 (306)
T ss_dssp             CCEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CCEEEECC-HHHHHHHHHHHHHCCCC
Confidence            77887664 44567788888887764


No 192
>1JFT_A PURINE NUCLEOTIDE SYNTHESIS REPRESSOR/DNA Complex; TRANSCRIPTION REGULATION, DNA-BINDING, REPRESSOR, PURINE; HET: HPA; 2.5A {Escherichia coli} SCOP: c.93.1.1, a.35.1.5
Probab=97.28  E-value=3.2e-07  Score=94.53  Aligned_cols=206  Identities=14%  Similarity=0.133  Sum_probs=119.1  Template_Neff=11.700

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...+.++||++.|..+.            .++.....+++.++++.|          +++.+.++..+.    +...+.+
T Consensus        54 ~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~----~~~~~~~  107 (340)
T 1JFT_A           54 KVNHTKSIGLLATSSEA------------AYFAEIIEAVEKNCFQKG----------YTLILGNAWNNL----EKQRAYL  107 (340)
T ss_dssp             HHTCCCEEEEEESCSCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHH
T ss_pred             ccCCCCEEEEEeCCCCc------------chHHHHHHHHHHHHHHcC----------CEEEEEeCCCCH----HHHHHHH
Confidence            34578899999987542            255677788888877653          233444443332    2223333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILR-LFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~-~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++..                   .++|++|+....... .....+. ..++|+|..+...+.      .++.+.+..++
T Consensus       108 ~~~~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~~~  161 (340)
T 1JFT_A          108 SMMAQ-------------------KRVDGLLVMCSEYPE-PLLAMLEEYRHIPMVVMDAGEAK------ADFTDAVIDNA  161 (340)
T ss_dssp             HHHHH-------------------TTCSEEEECCSCCCH-HHHHHHHTTTTSCEEESSCSSCC------CSSSEEEECCH
T ss_pred             HHHHh-------------------cCCCEEEEeCCCCCH-HHHHHHHHhcCCCEEEEcCCccC------CCCCcEEEeCH
Confidence            43332                   478888875443222 2233333 479999987764431      23445666666


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNAR  276 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~  276 (908)
                      ...++.+++++.+.++++++++..  +..++..+.++|++.+++. ++.+........+.+..+....++++++ ..++|
T Consensus       162 ~~~~~~~~~~l~~~g~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~d  240 (340)
T 1JFT_A          162 FEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEA-MIKVPESWIVQGDFEPESGYRAMQQILSQPHRPT  240 (340)
T ss_dssp             HHHHHHHHHHHHHHTCCCEEEECCCTTSCCCCCHHHHHHHHHHHH-TCCCCGGGBCCCCSSHHHHHHHHHHHHTSSSCCS
T ss_pred             HHHHHHHHHHHHHCCCCeEEEEeCCccccchHHHHHHHHHHHHHC-CCCCCHHHeeecCCChHHHHHHHHHHHcCCCCCC
Confidence            667778888876668889999985  3345667788888888765 3444321111100111233344555542 12477


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +|++.. +..+..+++++++.|+.
T Consensus       241 ~i~~~~-~~~~~~~~~~l~~~g~~  263 (340)
T 1JFT_A          241 AVFCGG-DIMAMGALCAADEMGLR  263 (340)
T ss_dssp             EEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEEECC-HHHHHHHHHHHHHcCCC
Confidence            777664 34456777788777763


No 193
>3BRS_B Periplasmic binding protein/LacI transcriptional regulator; STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE; 2.0A {Clostridium phytofermentans}
Probab=97.28  E-value=3.3e-07  Score=91.85  Aligned_cols=215  Identities=11%  Similarity=-0.043  Sum_probs=121.6  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||++.+.++..          ..++.....+++.++++.+        +++.+...|...+.    +...+.+++
T Consensus         3 ~~~~~i~~~~~~~g~~----------~~~~~~~~~g~~~a~~~~g--------~~~~~~~~~~~~~~----~~~~~~~~~   60 (289)
T 3BRS_B            3 LKQYYMICIPKVLDDS----------SDFWSVLVEGAQMAAKEYE--------IKLEFMAPEKEEDY----LVQNELIEE   60 (289)
T ss_dssp             --CCEEEEECSCCCSS----------CHHHHHHHHHHHHHHHHHT--------CEEEECCCSSTTCH----HHHHHHHHH
T ss_pred             CcceEEEEeecCCCCC----------ChHHHHHHHHHHHHHHHhC--------CEEEEECCCCCCCH----HHHHHHHHH
Confidence            4578899988875432          1355677888888888763        44555544432222    122333444


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   .+++++|+...+.. .......+...++|+|......+.      .++.+++.++...
T Consensus        61 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~~  115 (289)
T 3BRS_B           61 AIK-------------------RKPDVILLAAADYEKTYDAAKEIKDAGIKLIVIDSGMKQ------DIADITVATDNIQ  115 (289)
T ss_dssp             HHH-------------------TCCSEEEECCSCTTTTHHHHTTSGGGTCEEEEESCCCSS------CCCSEEEECCHHH
T ss_pred             HHH-------------------hCCCEEEEcCCChHhhHHHHHHHHHCCCEEEEECCCCCc------ccccEEEEcCHHH
Confidence            332                   47887776544332 224445566789999987654321      2456677777777


Q NP_000836.2     202 QAQAMVDIVTALG--WNYVSTLASE--GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNAR  276 (908)
Q Consensus       202 ~~~~~~~~l~~~~--~~~v~ii~~~--~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~  276 (908)
                      .++.+++++.+.+  .++++++...  ..++..+.+++++.+++. ++.+.......  .+..+....++++++ ..+++
T Consensus       116 ~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~  192 (289)
T 3BRS_B          116 AGIRIGAVTKNLVRKSGKIGVISFVKNSKTAMDREEGLKIGLSDD-SNKIEAIYYCD--SNYDKAYDGTVELLTKYPDIS  192 (289)
T ss_dssp             HHHHHHHHHHHHTSSSCEEEEEESCTTSHHHHHHHHHHHHHHGGG-GGGEEEEEECT--TCHHHHHHHHHHHHHHCTTEE
T ss_pred             HHHHHHHHHHHHhcCCceEEEEEccCCChHHHHHHHHHHHHHhcC-CCcEEEEEecC--CCHHHHHHHHHHHHHHCCCce
Confidence            7777877775544  6789988733  335666778888887764 34443211111  111223334455542 12467


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++.. +..+..+++++++.|...++.+++.
T Consensus       193 ~i~~~~-~~~a~~~~~~~~~~g~~~~~~i~~~  223 (289)
T 3BRS_B          193 VMVGLN-QYSATGAARAIKDMSLEAKVKLVCI  223 (289)
T ss_dssp             EEEESS-HHHHHHHHHHHHHTTCTTTCEEEEE
T ss_pred             EEEECC-hhhHHHHHHHHHHCCCcCCeEEEEE
Confidence            776553 4445667777777776323444443


No 194
>4RK4_A Transcriptional regulator, LacI family; sugar binding, transcription regulation, Enzyme; HET: GLC; 1.32A {Lactobacillus casei ATCC 334}
Probab=97.27  E-value=3.4e-07  Score=91.30  Aligned_cols=205  Identities=15%  Similarity=0.126  Sum_probs=115.7  Template_Neff=12.200

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++.++||+++|..+.            .++..+..+++.++++.+          +++.+.+...+.    +...+.+
T Consensus         5 ~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~   58 (283)
T 4RK4_A            5 RAQATGNIGVLVSRVTN------------PFFAGLFDAIERELHAHG----------YQVMITQTYDDP----EAEERFL   58 (283)
T ss_dssp             ----CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHH
T ss_pred             ccCCCCeEEEEEccCCC------------hhHHHHHHHHHHHHHHCC----------CEEEEEcCCCCH----HHHHHHH
Confidence            34568999999997542            255667778877776542          334444443332    2233344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++..                   .++|++|+...+... .....++..++|++..+...+.       +..+.+..++.
T Consensus        59 ~~l~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~~pvv~~~~~~~~-------~~~~~v~~d~~  111 (283)
T 4RK4_A           59 KQLKS-------------------RELDGVILASVEAPD-RVMAVAKAFPGRVVVVNADVQI-------PGATSLVLPHY  111 (283)
T ss_dssp             HHHHT-------------------TSSSEEEESCCSCHH-HHHHHHHHSTTSEEEESSSCCC-------TTSEEECCCHH
T ss_pred             HHHHh-------------------CCCCEEEEecCCCCH-HHHHHHHhCCCcEEEEcCCCCC-------CCCcEEEeChH
Confidence            44332                   478888875544333 3334556678998887654321       23455666666


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGN----YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE---TP  273 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~----~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~---~~  273 (908)
                      ..++.+++++.+.+.++++++..+..    .+..+.++|++.+++. ++.+..........+..+....+++++.   ..
T Consensus       112 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  190 (283)
T 4RK4_A          112 QATRDALDYLFNQGHRRFAYVSGGTISGAHHGQSRTQAFLDFMQAH-QLLVAQDLLFGQIHTAKEGQAVGKQLASLAPNV  190 (283)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEECSSCTTSSCTTHHHHHHHHHHHHHT-TCCCCGGGEECSCCSHHHHHHHHHHHHTSCTTT
T ss_pred             HHHHHHHHHHHHCCCCeEEEEeCCCCCCCcchHHHHHHHHHHHHHC-CCccchhHccCCCCChhHHHHHHHHHHHhCccC
Confidence            67777888877668889999885432    4556777888877764 3433221111100011122333344431   13


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++|+|++.. +..+..+++++++.|+.
T Consensus       191 ~~~~i~~~~-~~~a~~~~~al~~~g~~  216 (283)
T 4RK4_A          191 RPDAVFTNS-DEVAVGVIDSLLAADVK  216 (283)
T ss_dssp             SCSEEECSC-HHHHHHHHHHHHHTTCC
T ss_pred             CCCEEEECC-HHHHHHHHHHHHHCCCC
Confidence            678887664 44566788888887764


No 195
>4RK5_A Transcriptional regulator, LacI family; sugar binding, transcription regulation, Enzyme; HET: SUC; 1.35A {Lactobacillus casei ATCC 334}
Probab=97.27  E-value=3.4e-07  Score=91.30  Aligned_cols=205  Identities=15%  Similarity=0.126  Sum_probs=115.7  Template_Neff=12.200

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++.++||+++|..+.            .++..+..+++.++++.+          +++.+.+...+.    +...+.+
T Consensus         5 ~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~   58 (283)
T 4RK5_A            5 RAQATGNIGVLVSRVTN------------PFFAGLFDAIERELHAHG----------YQVMITQTYDDP----EAEERFL   58 (283)
T ss_dssp             ----CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHH
T ss_pred             ccCCCCeEEEEEccCCC------------hhHHHHHHHHHHHHHHCC----------CEEEEEcCCCCH----HHHHHHH
Confidence            34568999999997542            255667778877776542          334444443332    2233344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++..                   .++|++|+...+... .....++..++|++..+...+.       +..+.+..++.
T Consensus        59 ~~l~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~~pvv~~~~~~~~-------~~~~~v~~d~~  111 (283)
T 4RK5_A           59 KQLKS-------------------RELDGVILASVEAPD-RVMAVAKAFPGRVVVVNADVQI-------PGATSLVLPHY  111 (283)
T ss_dssp             HHHHT-------------------TSCSEEEESSCSCHH-HHHHHHHHSTTSEEEESSSCCC-------TTSEEECCCHH
T ss_pred             HHHHh-------------------CCCCEEEEecCCCCH-HHHHHHHhCCCcEEEEcCCCCC-------CCCcEEEeChH
Confidence            44332                   478888875544333 3334556678998887654321       23455666666


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGN----YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE---TP  273 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~----~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~---~~  273 (908)
                      ..++.+++++.+.+.++++++..+..    .+..+.++|++.+++. ++.+..........+..+....+++++.   ..
T Consensus       112 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  190 (283)
T 4RK5_A          112 QATRDALDYLFNQGHRRFAYVSGGTISGAHHGQSRTQAFLDFMQAH-QLLVAQDLLFGQIHTAKEGQAVGKQLASLAPNV  190 (283)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEECSSCTTSSCTTHHHHHHHHHHHHHT-TCCCCGGGEECSCCSHHHHHHHHHHHHTSCTTT
T ss_pred             HHHHHHHHHHHHCCCCeEEEEeCCCCCCCcchHHHHHHHHHHHHHC-CCccchhHccCCCCChhHHHHHHHHHHHhCccC
Confidence            67777888877668889999885432    4556777888877764 3433221111100011122333344431   13


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++|+|++.. +..+..+++++++.|+.
T Consensus       191 ~~~~i~~~~-~~~a~~~~~al~~~g~~  216 (283)
T 4RK5_A          191 RPDAVFTNS-DEVAVGVIDSLLAADVK  216 (283)
T ss_dssp             SCSEEECSC-HHHHHHHHHHHHHTTCC
T ss_pred             CCCEEEECC-HHHHHHHHHHHHHCCCC
Confidence            678887664 44566788888887764


No 196
>2QU7_B Putative transcriptional regulator; STRUCTURAL GENOMICS, TRANSCRIPTION, PSI-2, Protein; 2.3A {Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305}
Probab=97.26  E-value=3.6e-07  Score=91.52  Aligned_cols=200  Identities=12%  Similarity=0.073  Sum_probs=119.6  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|...             .++.....+++.++++.|          +++.+.++..++.    ...+.++
T Consensus         5 ~~~~~~I~~~~~~~~-------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~~----~~~~~~~   57 (288)
T 2QU7_B            5 TGRSNIIAFIVPDQN-------------PFFTEVLTEISHECQKHH----------LHVAVASSEENED----KQQDLIE   57 (288)
T ss_dssp             --CEEEEEEEESSCC-------------HHHHHHHHHHHHHHGGGT----------CEEEEEECTTCHH----HHHHHHH
T ss_pred             CCCCCEEEEEecCCC-------------hHHHHHHHHHHHHHHHCC----------CEEEEEeCCCCHH----HHHHHHH
Confidence            456889999999742             245677788888877653          2334444433321    2223344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   ++++++|+...+....   ..+...++|+|..+...+       .++.+++..++..
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~~~---~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~~  108 (288)
T 2QU7_B           58 TFVS-------------------QNVSAIILVPVKSKFQ---MKREWLKIPIMTLDRELE-------STSLPSITVDNEE  108 (288)
T ss_dssp             HHHH-------------------TTEEEEEECCSSSSCC---CCGGGTTSCEEEESSCCT-------TCCCCEEEECHHH
T ss_pred             HHHH-------------------CCCCEEEEecCCcchh---hhHHhcCCCEEEeCCCCC-------CCCCCEEEeChHH
Confidence            3332                   4788888765443322   234677999988765432       1345677777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPRE------PRPGEFEKIIKRLLETP  273 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~------~~~~~~~~~~~~l~~~~  273 (908)
                      .++.+++++.+.+.++++++..+.  .++..+.+++++.+++. ++.+.....+...      .+..+....+++++. .
T Consensus       109 ~~~~~~~~l~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~  186 (288)
T 2QU7_B          109 AAYIATKRVLESTCKEVGLLLANPNISTTIGRKNGYNKAISEF-DLNVNPSLIHYSDQQLGTNAQIYSGYEATKTLLS-K  186 (288)
T ss_dssp             HHHHHHHHHHTTTCCSEEEEECCTTSHHHHHHHHHHHHHHHHT-TCCCCGGGEEECCSSCSHHHHHHHHHHHHHHHHH-T
T ss_pred             HHHHHHHHHHHcCCCcEEEEecCCCCcchHHHHHHHHHHHHHC-CCCCCcccEEeecCCCCCchhHHHHHHHHHHHHh-c
Confidence            788888888777888999998543  35667788888888765 3433211111000      011223344555553 4


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++|+|++.. +..+..+++++++.|+.
T Consensus       187 ~~d~i~~~~-~~~a~~~~~~l~~~g~~  212 (288)
T 2QU7_B          187 GIKGIVATN-HLLLLGALQAIKESEKE  212 (288)
T ss_dssp             TCCEEEECS-HHHHHHHHHHHHHSSCC
T ss_pred             CCCEEEEcC-cHHHHHHHHHHHHcCCC
Confidence            788887764 44567788888877763


No 197
>4IRX_B Sugar ABC transporter, periplasmic sugar-binding; ABC transporter, periplasmic binding protein; HET: INS, MSE; 1.451A {Caulobacter crescentus}
Probab=97.26  E-value=3.7e-07  Score=91.76  Aligned_cols=208  Identities=13%  Similarity=0.057  Sum_probs=119.3  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++.++||++.|..+.            .++.....+++.++++.+          +++.+.|+..++.    ...+.+
T Consensus         4 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~l~~~~~~~~~~----~~~~~~   57 (296)
T 4IRX_B            4 PRGSHMEVVVSFNDLSQ------------PFFVAMRRELEDEAAKLG----------VKVQVLDAQNNSS----KQISDL   57 (296)
T ss_dssp             CCCSSCEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCHH----HHHHHH
T ss_pred             CCCCCcEEEEEeCCCCC------------HHHHHHHHHHHHHHHHcC----------CEEEEEeCCCCHH----HHHHHH
Confidence            45578999999986532            255677788888887753          3344555543322    223334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIG-AAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg-~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      ++++.                   +++++++. +..+.........+...++|+|..+...+.     ..++++++.+++
T Consensus        58 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~d~  113 (296)
T 4IRX_B           58 QAAAV-------------------QGAKVVIVAPTDSKALAGAADDLVEQGVAVISVDRNIAG-----GKTAVPHVGADN  113 (296)
T ss_dssp             HHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCEEEEESSCCCS-----SSSCCCEEEECH
T ss_pred             HHHHH-------------------CCCCEEEEecCChhhHHHHHHHHHHCCCEEEEEcCCCCC-----CCceeeEEecCh
Confidence            43332                   46776654 333332224445566789999987764331     134567777887


Q NP_000836.2     200 SYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE---T  272 (908)
Q Consensus       200 ~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~---~  272 (908)
                      ...++.+++++.+.  +.++++++..  ++.++..+.+++++.+++. +..+..........+..+....+++++.   .
T Consensus       114 ~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~  192 (296)
T 4IRX_B          114 VAGGRAMADWVVKTYPAGARVVVITNDPGSSSSIERVKGVHDGLAAG-GPAFKIVTEQTANSKRDQALTVTQNILTSMRD  192 (296)
T ss_dssp             HHHHHHHHHHHHHHCTTCEEEEEEESCTTSHHHHHHHHHHHHHHHHH-CTTEEEEEEEECTTCHHHHHHHHHHHHHHTTT
T ss_pred             HHHHHHHHHHHHHHCCCCCEEEEEEcCCCCchHHHHHHHHHHHHHcc-CCCcEEEeeecCCCCHHHHHHHHHHHHHhCCC
Confidence            77788888887654  5678998875  3345666777888877764 2332211111000111122233333331   1


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      .++++|++.. +..+..+++++++.|+.
T Consensus       193 ~~~~~i~~~~-~~~a~~~~~~l~~~g~~  219 (296)
T 4IRX_B          193 TPPDVILCLN-DDMAMGALEAVRAAGLD  219 (296)
T ss_dssp             SCCSEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CCCCEEEEcC-ChhHHHHHHHHHHCCCC
Confidence            3577776664 34466778888877763


No 198
>4RY9_A Periplasmic binding protein/LacI transcriptional regulator; SUGAR TRANSPORTER, ENZYME FUNCTION INITIATIVE; HET: GOL, TLZ; 1.4A {Verminephrobacter eiseniae EF01-2}
Probab=97.25  E-value=3.9e-07  Score=91.91  Aligned_cols=205  Identities=13%  Similarity=0.041  Sum_probs=116.9  Template_Neff=12.100

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++..+..+++.++++.+          +++.+.++..++.    ...+.++
T Consensus         4 ~~~~~~Ig~v~~~~~~------------~~~~~~~~~~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~   57 (302)
T 4RY9_A            4 QTGAFKIGVSMKTLSA------------PYFAAQMEAAKARGKELG----------YEVLATDAQGKLQ----KQISDVE   57 (302)
T ss_dssp             --CCCEEEEEESCCCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCHH----HHHHHHH
T ss_pred             cCCCeEEEEEECCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCHH----HHHHHHH
Confidence            3567899999987542            245567777777776632          3444555443321    2223334


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   .+++++|+...+.... .....+...++|+|..+...+.     ..++++++.+++.
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~~~~  113 (302)
T 4RY9_A           58 DLVT-------------------RGVKLLIINPADSEGLVNAVNNASANGVKVVVIDSTLNP-----RANFVTQVQSSNS  113 (302)
T ss_dssp             HHHH-------------------TTEEEEEEECSCTTTTHHHHHHHHHTTCEEEEESSCCCT-----TSCCSEEEECCHH
T ss_pred             HHHH-------------------CCCCEEEEecCCcccHHHHHHHHHHCCCEEEEECCCCCC-----cccceEEEecChh
Confidence            3332                   4788777654443322 3445566789999987754331     1345667777777


Q NP_000836.2     201 YQAQAMVDIVTA-L--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVC--------IAQSQKIPREPRPGEFEKIIK  267 (908)
Q Consensus       201 ~~~~~~~~~l~~-~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~--------v~~~~~~~~~~~~~~~~~~~~  267 (908)
                      ..+..+++++.+ .  +.++++++..  ++.++..+.+++++.+++. ++.        +.......  .+..+....++
T Consensus       114 ~~~~~~~~~l~~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~  190 (302)
T 4RY9_A          114 INGALVGHWVIEEVGNKSLKIALLSGEKGNPVGQERRLGVLSGIIEA-QLRKFGKADLTVVGQGWGH--WNDEGGLKAME  190 (302)
T ss_dssp             HHHHHHHHHHHHHHTTCCCEEEEEECCTTCHHHHHHHHHHHHHHHHH-HHHHHSCCCCEEEEEEECT--TSHHHHHHHHH
T ss_pred             HhHHHHHHHHHHHhCCCccEEEEEEcCCCChHHHHHHHHHHHHHHHH-HHHHhCCCCEEEEeeeecC--CCHHHHHHHHH
Confidence            777788887754 2  3578999985  3445666777788777664 232        21111111  11123444455


Q NP_000836.2     268 RLLET-PNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       268 ~l~~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +++.. .++++|++.. +..+..+++++++.|+.
T Consensus       191 ~~~~~~~~~~~i~~~~-~~~a~~~~~~~~~~g~~  223 (302)
T 4RY9_A          191 DLLVANKDINMVLGEN-DSMVLGARRAIESAGRT  223 (302)
T ss_dssp             HHHHHCSCCCEEEESS-HHHHHHHHHHHHHHTCC
T ss_pred             HHHHhCCCCCEEEeCC-hHHHHHHHHHHHHcCCC
Confidence            55421 2466666553 44566778888877764


No 199
>3G1W_A Sugar ABC transporter; Sugar ABC transporter, Sugar-binding protein; 2.02A {Bacillus halodurans C-125}
Probab=97.24  E-value=4e-07  Score=92.08  Aligned_cols=213  Identities=14%  Similarity=0.059  Sum_probs=117.4  Template_Neff=11.700

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILD-TCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d-~~~~~~~a~~~~~~~~~  121 (908)
                      .++++||++.|....            .++.....+++.++++.+        +  ++.+.+ +..++    +...+.++
T Consensus         2 ~~~~~Igvl~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~~----~~~~~~~~   55 (305)
T 3G1W_A            2 SLNETYMMITFQSGM------------DYWKRCLKGFEDAAQALN--------V--TVEYRGAAQYDI----QEQITVLE   55 (305)
T ss_dssp             ---CEEEEEESSTTS------------THHHHHHHHHHHHHHHHT--------C--EEEEEECSSSCH----HHHHHHHH
T ss_pred             CCCeEEEEEecCCCC------------hHHHHHHHHHHHHHHHcC--------C--EEEEecccCCCH----HHHHHHHH
Confidence            357899999997632            245567778887777642        3  333444 32222    12223333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   ++++++|+...+... ......+...++|+|..+...+.      .++++++.++..
T Consensus        56 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  110 (305)
T 3G1W_A           56 QAIA-------------------KNPAGIAISAIDPVELTDTINKAVDAGIPIVLFDSGAPD------SHAHSFLGTNNY  110 (305)
T ss_dssp             HHHH-------------------HCCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCTT------SCCSCEEECCHH
T ss_pred             HHHH-------------------cCCCEEEEeCCCHHHHHHHHHHHHHCCCCEEEEcCCCCC------ccccEEEeCCHH
Confidence            3332                   467877764433322 23445566779999987654321      245667777777


Q NP_000836.2     201 YQAQAMVDIVTAL--GWNYVSTLASEG-NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~--~~~~v~ii~~~~-~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ..+..+++++.+.  +.++++++.... .....+.+++++.+++. +..+..........+..+....++++++. .++|
T Consensus       111 ~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d  189 (305)
T 3G1W_A          111 NAGMNAAYKMAELLDGEGEVAVITLPNQLNHQERTTGFKETLEAE-FPAIEVIAVEDGRGDSLHSRRVAHQLLEDYPNLA  189 (305)
T ss_dssp             HHHHHHHHHHHHHTTTCEEEEEEECTTCHHHHHHHHHHHHHHHHH-CTTEEEEEEEECTTCHHHHHHHHHHHHHHCTTEE
T ss_pred             HHHHHHHHHHHHHcCCCcEEEEEECCCcccHHHHHHHHHHHHHHH-CCCeEEEEEecCCCChHHHHHHHHHHHHHCCCcc
Confidence            7777888887655  778999998532 45566777888877654 23222111111001112334445555421 2477


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++.. +..+..+++++++.+...++.+++.
T Consensus       190 ~i~~~~-~~~a~~~~~~l~~~~~~~~v~ii~~  220 (305)
T 3G1W_A          190 GIFATE-ANGGVGVGDAVRLESRAGEIQIISF  220 (305)
T ss_dssp             EEEESS-HHHHHHHHHHHHHTTCTTTSEEEEE
T ss_pred             EEEEec-CCcchHHHHHHHHccCCCCEEEEEE
Confidence            787664 3455667777777664323444443


No 200
>3G1W_B Sugar ABC transporter; Sugar ABC transporter, Sugar-binding protein; HET: MSE; 2.02A {Bacillus halodurans C-125}
Probab=97.24  E-value=4e-07  Score=92.08  Aligned_cols=213  Identities=14%  Similarity=0.059  Sum_probs=118.2  Template_Neff=11.700

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILD-TCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d-~~~~~~~a~~~~~~~~~  121 (908)
                      .++++||++.|....            .++.....+++.++++.+        +  ++.+.+ +..++    +...+.++
T Consensus         2 ~~~~~Igvl~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~~----~~~~~~~~   55 (305)
T 3G1W_B            2 SLNETYMMITFQSGM------------DYWKRCLKGFEDAAQALN--------V--TVEYRGAAQYDI----QEQITVLE   55 (305)
T ss_dssp             --CCEEEEEEESTTS------------THHHHHHHHHHHHHHHHT--------C--EEEEEEESSSCH----HHHHHHHH
T ss_pred             CCCeEEEEEecCCCC------------hHHHHHHHHHHHHHHHcC--------C--EEEEecccCCCH----HHHHHHHH
Confidence            357899999997632            245567778887777642        3  333444 32222    12223333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   ++++++|+...+... ......+...++|+|..+...+.      .++++++.++..
T Consensus        56 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  110 (305)
T 3G1W_B           56 QAIA-------------------KNPAGIAISAIDPVELTDTINKAVDAGIPIVLFDSGAPD------SHAHSFLGTNNY  110 (305)
T ss_dssp             HHHH-------------------HCCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCTT------SCCSCEEECCHH
T ss_pred             HHHH-------------------cCCCEEEEeCCCHHHHHHHHHHHHHCCCCEEEEcCCCCC------ccccEEEeCCHH
Confidence            3332                   467877764433322 23445566779999987654321      245667777777


Q NP_000836.2     201 YQAQAMVDIVTAL--GWNYVSTLASEG-NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~--~~~~v~ii~~~~-~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ..+..+++++.+.  +.++++++.... .....+.+++++.+++. +..+..........+..+....++++++. .++|
T Consensus       111 ~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d  189 (305)
T 3G1W_B          111 NAGMNAAYKMAELLDGEGEVAVITLPNQLNHQERTTGFKETLEAE-FPAIEVIAVEDGRGDSLHSRRVAHQLLEDYPNLA  189 (305)
T ss_dssp             HHHHHHHHHHHHHTTTCEEEEEEECTTCHHHHHHHHHHHHHHHHH-CTTEEEEEEEECTTCHHHHHHHHHHHHHHCTTEE
T ss_pred             HHHHHHHHHHHHHcCCCcEEEEEECCCcccHHHHHHHHHHHHHHH-CCCeEEEEEecCCCChHHHHHHHHHHHHHCCCcc
Confidence            7777888887655  778999998532 45566777888877654 23222111111001112334445555421 2477


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++.. +..+..+++++++.+...++.+++.
T Consensus       190 ~i~~~~-~~~a~~~~~~l~~~~~~~~v~ii~~  220 (305)
T 3G1W_B          190 GIFATE-ANGGVGVGDAVRLESRAGEIQIISF  220 (305)
T ss_dssp             EEEESS-HHHHHHHHHHHHHTTCTTTSEEEEE
T ss_pred             EEEEec-CCcchHHHHHHHHccCCCCEEEEEE
Confidence            787664 3455667777777664323444443


No 201
>5XSD_B Periplasmic binding protein/LacI transcriptional regulator; Two component system, histidine kinase; 2.5A {Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)}
Probab=97.23  E-value=4.3e-07  Score=91.87  Aligned_cols=217  Identities=17%  Similarity=0.071  Sum_probs=121.3  Template_Neff=11.900

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ......++||++.|..+.            .++..+..+++.++++.+        +++.+...+. .++    +...+.
T Consensus        13 ~~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~~~~~~   67 (306)
T 5XSD_B           13 EKEPIKPKIVLISHIKTN------------PYWLDIKAGAERAAKERG--------AVVEFLGPTT-AST----EDGLKL   67 (306)
T ss_dssp             ---CCCCEEEEECSCSSC------------HHHHHHHHHHHHHHHHHT--------CEEEEECCSS-CCH----HHHHHH
T ss_pred             cCCCCCCeEEEEecCCCC------------HHHHHHHHHHHHHHHHcC--------CEEEEeCCCC-CCH----HHHHHH
Confidence            345578999999986542            255677888888887753        3444433222 221    122233


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVI-GAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      ++++..                   .++|++| ++..+.........+...++|+|..+...+.      .++++++.++
T Consensus        68 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d  122 (306)
T 5XSD_B           68 FDMATS-------------------AKVSGIITYVQEEGQYKKKINSAMEKGIPVVTIASDEED------SNRIAYVGTD  122 (306)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCCS------SCCSEEEEEC
T ss_pred             HHHHHh-------------------CCCCEEEEeCCChhHHHHHHHHHHHCCCCEEEEcCCCCC------cCCeEEEecC
Confidence            333332                   4778777 4433332223445566789999987654321      2456677777


Q NP_000836.2     199 DSYQAQAMVDIVTAL-GW-NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-P  273 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~-~~-~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~  273 (908)
                      ....+..+++++.+. +. ++++++..  ++.++..+.++|++.+++.+.+.+.......  .+..+....+++++.. .
T Consensus       123 ~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~  200 (306)
T 5XSD_B          123 NVLAGQVAGKEMVKQIGTSGNVAIVMGGKNVKNQKERVEGFTQYIKSNSNLKIVDTDSSD--AMLLEAEIITRKILNRND  200 (306)
T ss_dssp             HHHHHHHHHHHHHHHHCSSSEEEEECSCTTCHHHHHHHHHHHHHHHHHCCCEEECCCCTT--TTTCCHHHHHHHHHHHCT
T ss_pred             HHHHHHHHHHHHHHHHCCCceEEEEECCCCcccHHHHHHHHHHHHHhcCCcEEeeeecCc--hhHHHHHHHHHHHHHhCC
Confidence            777777888887654 65 88998875  3345667778888877764213332211111  1112233445555421 2


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSD  309 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~  309 (908)
                      ++++|++.. +..+..+++++++.|+..++.+++.+
T Consensus       201 ~~~~i~~~~-~~~a~~~~~~~~~~g~~~~~~vi~~~  235 (306)
T 5XSD_B          201 NINALFCTS-ALDGIGAARAVKDLNYKDRVKIICFD  235 (306)
T ss_dssp             TCCEEEESS-HHHHHHHHHHHHHTTCBTTBEEEEES
T ss_pred             CCCEEEECC-cchHHHHHHHHHHcCCCCCeEEEEeC
Confidence            467776654 44566777777777763234444443


No 202
>5DKV_A ABC transporter substrate binding protein; Solute Binding Protein, ENZYME FUNCTION; HET: T6T; 1.68A {Agrobacterium vitis (strain S4 / ATCC BAA-846)}
Probab=97.23  E-value=4.3e-07  Score=92.85  Aligned_cols=219  Identities=10%  Similarity=0.013  Sum_probs=124.2  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDT-CSRDTYALEQSLTFV  120 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~-~~~~~~a~~~~~~~~  120 (908)
                      .++.++||++.|..+.            ..+.....+++.++++.|        +  ++.+.+. ..++    +...+.+
T Consensus        24 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~l~~~~~~~~~~----~~~~~~~   77 (324)
T 5DKV_A           24 ENKKFRIALIPGLTTD------------AFYITMHKGAEAAAAAIG--------A--QIIFQGAPDFNP----VTQVPVL   77 (324)
T ss_dssp             SSCCCEEEEECSCSSC------------HHHHHHHHHHHHHHHHHT--------C--EEEECCCSSSCH----HHHHHHH
T ss_pred             cCCCcEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC--------C--EEEEeCCCCCCH----HHHHHHH
Confidence            3468999999887542            245677788888887753        2  3333433 2222    2233344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELS----DNTRYDFFSRV  195 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~----~~~~~~~~~~~  195 (908)
                      ++++.                   ++++++|+...+... ......+...++|+|..+...+...    .....++++++
T Consensus        78 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~~~~~~~~~~~~~~v  138 (324)
T 5DKV_A           78 DAVIA-------------------KKPDAILIAPTDTTQLVQPLKKAADAGIPMITVDTFIGTGDYQTGAGDGDFPLSYI  138 (324)
T ss_dssp             HHHHT-------------------TCCSEEEECCSCTTTTHHHHHHHHHTTCCEEEESSCSTTSCCSSSCSTTCCSSCEE
T ss_pred             HHHHH-------------------hCCCEEEECCCCchHhHHHHHHHHHCCCCEEEEcCCCCCCcccCCCCCCCCCcEEE
Confidence            44332                   467877764433322 2444556678999998775433100    00013456777


Q NP_000836.2     196 VPPDSYQAQAMVDIVT-ALGWNYVSTLAS---EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~-~~~~~~v~ii~~---~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      .++....++.+++++. +.+.++++++..   ++.++..+.++|++.+++..++.+.......  .+..+....+++++.
T Consensus       139 ~~d~~~~~~~~~~~l~~~~~~~~~~~i~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~  216 (324)
T 5DKV_A          139 ASDNVLGGEIAARSLALAIGDKGKVYVSNVKPGVSTTDQREQGFKSEMAKHPGITVLETQFND--NDANKAASQLQAVYA  216 (324)
T ss_dssp             EECHHHHHHHHHHHHHHHTTTCEEEEEEESCTTCHHHHHHHHHHHHHHTTCTTEEECCCEECT--TCHHHHHHHHHHHHH
T ss_pred             ecCHHHHHHHHHHHHHHHHCCCceEEEEEcCCCCChHHHHHHHHHHHHhhCCCcEEEEeeeCC--CCHHHHHHHHHHHHH
Confidence            7887777888888874 667788888875   3345667778888877654124433221111  112234445555543


Q NP_000836.2     272 T-PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       272 ~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      . .++++|++.. +..+..+++++++.|...++.+++.
T Consensus       217 ~~~~~~~i~~~~-~~~a~~~~~al~~~g~~~~i~i~~~  253 (324)
T 5DKV_A          217 RNPDLAGVFGAN-LFSGLGSANGVQQAGQSGTIKVVAF  253 (324)
T ss_dssp             HCTTCCEEEECS-HHHHHHHHHHHHHTTCBTTBEEEEE
T ss_pred             HCCCccEEEEcC-cchhHHHHHHHHHcCCCCceEEEEe
Confidence            1 2467776654 4456678888887776323444443


No 203
>1ZVV_B Glucose-resistance amylase regulator/HPr-like protein crh/DNA; ccpa  crh  dna; HET: SEP, IOD; 2.98A {Bacillus subtilis} SCOP: c.93.1.1, a.35.1.5
Probab=97.23  E-value=4.3e-07  Score=93.15  Aligned_cols=204  Identities=11%  Similarity=0.116  Sum_probs=120.1  Template_Neff=11.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++..+..+++.++++.+        +  ++.+.+...++    +...+.++
T Consensus        57 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~~  110 (332)
T 1ZVV_B           57 SKKTTTVGVIIPDISN------------IFYAELARGIEDIASMYK--------Y--NIILSNSDQNQ----DKQLHLLN  110 (332)
T ss_dssp             HTCCSEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------C--EEEEEECTTCH----HHHHHHHH
T ss_pred             cCCCCEEEEEeCCCCC------------hHHHHHHHHHHHHHHHcC--------C--eEEEEeCCCCH----HHHHHHHH
Confidence            4568899999987542            245667778887777642        2  33444443332    12223344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+. .......+...++|+|..+...+       .+..+.+.++...
T Consensus       111 ~l~~-------------------~~~d~ii~~~~~~-~~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  163 (332)
T 1ZVV_B          111 NMLG-------------------KQVDGIIFMSGNV-TEEHVEELKKSPVPVVLAASIES-------TNQIPSVTIDYEQ  163 (332)
T ss_dssp             HHHH-------------------HTCSEEEECCSCC-CHHHHHHHTTCSSCEEEESCCCT-------TCCSCEECCCHHH
T ss_pred             HHHh-------------------CCCCEEEEeCCCC-CHHHHHHHHhCCCCEEEECCCCC-------CCCCCEEEeCHHH
Confidence            4332                   4788888754443 23445556678999998765322       1345566667767


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      .+..+++++.+.+.+++++++.+..   .+..+.+++++.+++. ++.+.....+..+.+..+....+++++. ..++|+
T Consensus       164 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  242 (332)
T 1ZVV_B          164 AAFDAVQSLIDSGHKNIAFVSGTLEEPINHAKKVKGYKRALTES-GLPVRDSYIVEGDYTYDSGIEAVEKLLEEDEKPTA  242 (332)
T ss_dssp             HHHHHHHHHHHTTCCCEEEECSCTTSHHHHTTHHHHHHHHHHHH-TCCCCTTSCCCCCSSHHHHHHHHHHHHSSSSCCSE
T ss_pred             HHHHHHHHHHHCCCCcEEEEeCCCCCcccHHHHHHHHHHHHHHc-CCCCCHHHeecCCCCHHHHHHHHHHHHhcCCCCCE
Confidence            7777888876668889999985433   4567778888887764 3443221111111112234445555542 136788


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|..
T Consensus       243 i~~~~-~~~a~~~~~~l~~~g~~  264 (332)
T 1ZVV_B          243 IFVGT-DEMALGVIHGAQDRGLN  264 (332)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            87664 44556777888877763


No 204
>4KQ9_A Ribose ABC transporter, substrate binding; ABC transporter, ribose binding, PSI-Biology; HET: GOL; 1.9A {Conexibacter woesei}
Probab=97.22  E-value=4.6e-07  Score=91.20  Aligned_cols=205  Identities=13%  Similarity=-0.005  Sum_probs=119.4  Template_Neff=12.100

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|....            .++.....+++.++++.+          +++.+.|+..++.    ...+.++
T Consensus         4 ~~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~   57 (299)
T 4KQ9_A            4 SAAGKKVVYSTFGAQI------------PFFNRIGEGAKAQATVRR----------LDFDISTSEIDPG----KQIDSID   57 (299)
T ss_dssp             CCTTCEEEEEEECTTC------------HHHHHHHHHHHHHHHHTT----------CEEEEEEECSSHH----HHHHHHH
T ss_pred             ccCceEEEEEeCCCCC------------HHHHHHHHHHHHHHHHcC----------CeEEEecCCCCHH----HHHHHHH
Confidence            4568899999983221            355677788888777632          3444455444322    2233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI-MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~-~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   .+++++|+...+.... .....+...++|+|..+...+.     ..++++++.+++.
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~-----~~~~~~~v~~d~~  113 (299)
T 4KQ9_A           58 NAVA-------------------QQPDGLIVSPIDGSALVPTIKGAVEDGVPVILLADGLSE-----DVGQLSFVGSDFA  113 (299)
T ss_dssp             HHHH-------------------TCCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCSS-----CCCCSEEEECCHH
T ss_pred             HHHH-------------------cCCCEEEECCCCccccHHHHHHHHHCCCcEEEECCCCCC-----cccceEEEEcCHH
Confidence            3332                   4778777644333221 3445566789999987654321     1345677778887


Q NP_000836.2     201 YQAQAMVDIVTAL-G-WNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNA  275 (908)
Q Consensus       201 ~~~~~~~~~l~~~-~-~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~  275 (908)
                      ..++.+++++.+. + .++++++..+.  .++..+.++|++.+++. ++.+........ .+..+....+.++++ ..++
T Consensus       114 ~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~  191 (299)
T 4KQ9_A          114 EIGRLKATYIADRLGDGGTVAMVNGTRGMSFVEEQGEAAREVFEER-GIEIVDDVYTKA-ITPDEGLTATQNILTRHSDV  191 (299)
T ss_dssp             HHHHHHHHHHHHHCCTTCEEEEECCSTTCHHHHHHHHHHHHHHHHH-TCEEEEEECCSS-SCHHHHHHHHHHHHHHCTTC
T ss_pred             HHHHHHHHHHHHHhCCCcEEEEEeCCCCChHHHHHHHHHHHHHHhc-CcEEecccccCC-CCHHHHHHHHHHHHHhCCCC
Confidence            7788888887654 6 68999998533  35666778888887765 344432111110 111233344555542 1356


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      ++|++.. +..+..+++++++.|+
T Consensus       192 ~~i~~~~-~~~~~~~~~~l~~~g~  214 (299)
T 4KQ9_A          192 GAIYYSG-DDGALGGIRAIAARNI  214 (299)
T ss_dssp             CEEEESS-HHHHHHHHHHHHHTTC
T ss_pred             CEEEEcC-cchHHHHHHHHHHCCC
Confidence            7776654 3455667788877776


No 205
>5XSS_A Periplasmic binding protein/LacI transcriptional regulator; Two component system, histidine kinase; HET: XYP; 2.093A {Clostridium beijerinckii (strain ATCC 51743 / NCIMB 8052)}
Probab=97.21  E-value=4.8e-07  Score=92.12  Aligned_cols=217  Identities=16%  Similarity=0.063  Sum_probs=119.7  Template_Neff=11.400

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      ....++.++||++.|..+.            .++..+..+++.++++.+        +++.+...+. .++    +...+
T Consensus        22 ~~~~~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~a~~~~g--------~~~~~~~~~~-~~~----~~~~~   76 (316)
T 5XSS_A           22 VEKEPIKPKIVLISHIKTN------------PYWLDIKAGAERAAKERG--------AVVEFLGPTT-AST----EDGLK   76 (316)
T ss_dssp             ------CCEEEEECSSTTC------------HHHHHHHHHHHHHHHHHT--------CEEEEECCSS-CCH----HHHHH
T ss_pred             ccCCCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHcC--------CEEEEeCCCC-CCH----HHHHH
Confidence            3456678999999986542            255677788888887753        3444433222 121    12223


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIG-AAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg-~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .++.+..                   +++|++|. +............+...++|+|..+...+.      .++++++.+
T Consensus        77 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~  131 (316)
T 5XSS_A           77 LFDMATS-------------------AKVSGIITYVQEEGQYKKKINSAMEKGIPVVTIDSDEED------SNRIAYVGT  131 (316)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCCSTTSSHHHHHHHHHTTCCEEEESSCCCS------SCCSEEESB
T ss_pred             HHHHHHH-------------------cCCCEEEEccCCcchhHHHHHHHHHCCCCEEEEcCCCCC------CCCeEEEeC
Confidence            3333332                   47787774 333322223444566789999987654321      245677777


Q NP_000836.2     198 PDSYQAQAMVDIVTAL-GW-NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-  272 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~-~~-~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-  272 (908)
                      +....+..+++++.+. +. ++++++..  ++.++..+.++|++.+++.+.+.+.......  ....+....++++++. 
T Consensus       132 d~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~  209 (316)
T 5XSS_A          132 DNVLAGQVAGKEMVKQIGTSGNVAIVMGGKNVKNQKERVEGFTQYIKSNSNLKIVDTDSSD--AMLLEAEIITRKILNRN  209 (316)
T ss_dssp             CHHHHHHHHHHHHHHHHCSSSEEEEEESCTTCHHHHHHHHHHHHHHHHHCCCEEEEEEECT--TCHHHHHHHHHHHHHHC
T ss_pred             CHHHHHHHHHHHHHHHHCCCceEEEEECCCCchhHHHHHHHHHHHHHhcCCcEEeEEecCc--hHHHHHHHHHHHHHHhC
Confidence            7777788888887654 65 88998875  3345667778888877764213332211111  1111233445555421 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      .++++|++.. +..+..+++++++.|+..++.+++.
T Consensus       210 ~~~~~i~~~~-~~~a~~~~~al~~~g~~~~~~iig~  244 (316)
T 5XSS_A          210 DNINALFCTS-ALDGIGAARAVKDLNYKDRVKIICF  244 (316)
T ss_dssp             SCCCEEEECS-HHHHHHHHHHHHHTTCTTTSEEEEE
T ss_pred             CCcCEEEECC-chhHHHHHHHHHHcCCCCCeEEEEe
Confidence            2467776654 3446677778877776323444443


No 206
>4YR7_A LuxP; PROTEIN-LIGAND COMPLEX, QUORUM SENSING, signaling; HET: A1B; 2.533A {Vibrio harveyi}
Probab=97.20  E-value=5.1e-07  Score=93.23  Aligned_cols=222  Identities=11%  Similarity=0.029  Sum_probs=124.2  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|..+..           ........+++.++++.+.      .+.+++.+.|+..++.    ...+.++
T Consensus        43 ~~~~~~Ig~i~~~~~~~-----------~~~~~~~~g~~~~~~~~g~------~~~l~~~~~d~~~~~~----~~~~~~~  101 (345)
T 4YR7_A           43 TQRPIKISVVYPGQQVS-----------DYWVRNIASFEKRLYKLNI------NYQLNQVFTRPNADIK----QQSLSLM  101 (345)
T ss_dssp             CSSCEEEEEEEECSCSC-----------CHHHHHHHHHHHHHHHTTC------CEEEEEEEECTTCCHH----HHHHHHH
T ss_pred             CCCCeEEEEEecCCCCC-----------HHHHHHHHHHHHHHHHcCC------cEEEEEeecCCCCCHH----HHHHHHH
Confidence            56789999999975322           1334778888888888642      1222224455444322    2333344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRL-FKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~-~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   ++++++|+...+.........+.. .++|+|..+...+.... ...++.+++.+++.
T Consensus       102 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~-~~~~~~~~v~~d~~  161 (345)
T 4YR7_A          102 EALK-------------------SKSDYLIFTLDTTRHRKFVEHVLDSTNTKLILQNITTPVREW-DKHQPFLYVGFDHA  161 (345)
T ss_dssp             HHHH-------------------TCCSEEEECCCTTTSHHHHHHHHTTCSSEEEEETCCSCBGGG-GGSCCSEEEECCHH
T ss_pred             HHHH-------------------cCCCEEEEeCCchhhHHHHHHHHHhCCCeEEEEcCCCCcchh-ccCCCeEEEEcChH
Confidence            4332                   478888876543333333444444 79999987654432111 11346677888888


Q NP_000836.2     201 YQAQAMVDIVTALGWN--YVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~--~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ..++.+++++.+.+.+  +++++..+ +.++..+.++|++.+++.+++++.......  .+..+....+++++.. .+++
T Consensus       162 ~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~  239 (345)
T 4YR7_A          162 EGSRELATEFGKFFPKHTYYSVLYFSEGYISDVRGDTFIHQVNRDNNFELQSAYYTK--ATKQSGYDAAKASLAKHPDVD  239 (345)
T ss_dssp             HHHHHHHHHHHHHSCTTCEEEEECCSTTHHCCCCCCHHHHHHHHHHCCEEEEEECCC--SSHHHHHHHHHHHHHHCCCCS
T ss_pred             HHHHHHHHHHHHhCCCCCeEEEEEecCCchhHHHHHHHHHHHHhcCCceEeeccccC--CCHHHHHHHHHHHHHHCCCCc
Confidence            8888888887654443  48888754 446667778888877653223333211111  1122344455555431 2345


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|++. ++..+..+++++++.|. .++.+++.
T Consensus       240 ~i~~~-~~~~a~~~~~al~~~g~-~~i~i~g~  269 (345)
T 4YR7_A          240 FIYAC-STDVALGAVDALAELGR-EDIMINGW  269 (345)
T ss_dssp             EEEES-SHHHHHHHHHHHHHHTC-TTSEEBCS
T ss_pred             EEEEC-ChHHHHHHHHHHHHcCC-CCcEEEee
Confidence            55544 34455667888887776 23344443


No 207
>2IOY_A Periplasmic sugar-binding proteins; Ribose binding protein, sugar binding; HET: RIP; 1.9A {Thermoanaerobacter tengcongensis}
Probab=97.19  E-value=5.3e-07  Score=89.96  Aligned_cols=208  Identities=13%  Similarity=0.145  Sum_probs=116.2  Template_Neff=11.900

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIE  125 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~~  125 (908)
                      .+||++.|..+.            .++.....+++.++++.+          +++.+.++..++.    ...+.++++..
T Consensus         2 ~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~~----------~~l~~~~~~~~~~----~~~~~~~~l~~   55 (283)
T 2IOY_A            2 KTIGLVISTLNN------------PFFVTLKNGAEEKAKELG----------YKIIVEDSQNDSS----KELSNVEDLIQ   55 (283)
T ss_dssp             CEEEEEESCSSS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCHH----HHHHHHHHHHH
T ss_pred             cEEEEEecCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEECCCCCHH----HHHHHHHHHHh
Confidence            578999986542            245667778877777642          3344455433322    22233333332


Q NP_000836.2     126 KDASDVKCANGDPPIFTKPDKISGVIG-AAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       126 ~~~~~~~~~~~~~~~~~~~~~v~~vIg-~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                                         ++++++|. +..+.........+...++|+|..+...+.      .++.+++.++....++
T Consensus        56 -------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~d~~~~~~  110 (283)
T 2IOY_A           56 -------------------QKVDVLLINPVDSDAVVTAIKEANSKNIPVITIDRSANG------GDVVCHIASDNVKGGE  110 (283)
T ss_dssp             -------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCSS------SCCSEEEEECHHHHHH
T ss_pred             -------------------CCCCEEEECCCChhHHHHHHHHHHHCCCCEEEEcCCCCC------CCeEEEEecChHHHHH
Confidence                               46776665 333322223344456689999987754321      2456677777777788


Q NP_000836.2     205 AMVDIVTA--LGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAVI  279 (908)
Q Consensus       205 ~~~~~l~~--~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~viv  279 (908)
                      .+++++.+  .+.++++++..  ++.++..+.++|++.+++.++..+.......  .+..+....++++++ ..++|+|+
T Consensus       111 ~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~d~i~  188 (283)
T 2IOY_A          111 MAAEFIAKALKGKGNVVELEGIPGASAARDRGKGFDEAIAKYPDIKIVAKQAAD--FDRSKGLSVMENILQAQPKIDAVF  188 (283)
T ss_dssp             HHHHHHHHHTTTCEEEEEEECCTTCHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHCSCCCEEE
T ss_pred             HHHHHHHHHcCCCeEEEEEECCCCChhHHHHHHHHHHHHHhCCCeEEEEeecCC--CCHHHHHHHHHHHHHHCCCCCEEE
Confidence            88888765  47789999974  3455667778888877664223332111111  111233344445432 13577776


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +.. +..+..+++++++.|.. ++.+++.
T Consensus       189 ~~~-~~~a~~~~~~l~~~g~~-~~~iig~  215 (283)
T 2IOY_A          189 AQN-DEMALGAIKAIEAANRQ-GIIVVGF  215 (283)
T ss_dssp             ESS-HHHHHHHHHHHHHTTCC-CCEEEEE
T ss_pred             EcC-hhHHHHHHHHHHHcccC-CcEEEEe
Confidence            654 34566677777776652 2344443


No 208
>1TLF_C TRYPTIC CORE FRAGMENT OF THE; TRANSCRIPTION REGULATION; HET: IPT, EMC; 2.6A {Escherichia coli} SCOP: c.93.1.1
Probab=97.19  E-value=5.3e-07  Score=91.01  Aligned_cols=200  Identities=12%  Similarity=0.076  Sum_probs=116.5  Template_Neff=11.500

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++..+..+++.++++.+        +++.+...+. .+.    +...+.+++++
T Consensus         2 ~~~Ig~v~~~~~~------------~~~~~~~~~~~~a~~~~g--------~~l~~~~~~~-~~~----~~~~~~~~~l~   56 (301)
T 1TLF_C            2 SLLIGVATSSLAL------------HAPSQIVAAIKSRADQLG--------ASVVVSMVER-SGV----EACKAAVHNLL   56 (301)
T ss_dssp             CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------CEEEEEECCS-SSH----HHHHHHHHHHH
T ss_pred             CceEEEEeCcccc------------chHHHHHHHHHHHHHHcC--------CEEEEEecCC-CcH----HHHHHHHHHHH
Confidence            5789999997542            255677788888887753        3333332221 111    12233444433


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   .+++++|+...+.........+...++|+|..+...+        +.++.+.++....+.
T Consensus        57 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~--------~~~~~v~~d~~~~~~  109 (301)
T 1TLF_C           57 A-------------------QRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQ--------TPINSIIFSHEDGTR  109 (301)
T ss_dssp             T-------------------TTCSEEEEESCCCHHHHHHHHHHSTTSCEEESSSCTT--------SSSEEEEECHHHHHH
T ss_pred             h-------------------CCCCEEEEeCCCCchHHHHHHHHHcCCCEEEEeCCCC--------CCCCeEEeccHHHHH
Confidence            2                   4788888765443322222235678999988765332        234556666666677


Q NP_000836.2     205 AMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAVIMF  281 (908)
Q Consensus       205 ~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~viv~~  281 (908)
                      .+++++.+.+.++++++..  +..+...+.++|++.+++. ++++.......  .+..+....+++++.. .++|+|++.
T Consensus       110 ~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~daii~~  186 (301)
T 1TLF_C          110 LGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRN-QIQPIAEREGD--WSAMSGFQQTMQMLNEGIVPTAMLVA  186 (301)
T ss_dssp             HHHHHHHHHTCCSEEEEECCTTSHHHHHHHHHHHHHHHHT-TCCCSEEEECC--SSHHHHHHHHHHHHHTTCCCSEEEES
T ss_pred             HHHHHHHHCCCCeEEEEeCCCCCHHHHHHHHHHHHHHHHC-CCCCeeeecCC--CChHHHHHHHHHHHHcCCCCCEEEEC
Confidence            7788776668889999985  3345666778888888775 35443211111  1112233445555421 247788766


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~  300 (908)
                      . +..+..+++++++.|+.
T Consensus       187 ~-~~~a~~~~~~l~~~g~~  204 (301)
T 1TLF_C          187 N-DQMALGAMRAITESGLR  204 (301)
T ss_dssp             S-HHHHHHHHHHHHHTTCC
T ss_pred             C-hHHHHHHHHHHHHcCCC
Confidence            4 44567788888877764


No 209
>3OQO_C Catabolite control protein A, Phosphocarrier; pbp fold for ccpa, transcription; HET: SEP, SO4; 2.97A {Bacillus subtilis}
Probab=97.19  E-value=5.3e-07  Score=92.84  Aligned_cols=204  Identities=9%  Similarity=0.065  Sum_probs=119.3  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++.....+++.++++.+        +  ++.+.+...++    +...+.++
T Consensus        57 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~~  110 (339)
T 3OQO_C           57 SKKTTTVGVIIPDISS------------IFYSELARGIEDIATMYK--------Y--NIILSNSDQNM----EKELHLLN  110 (339)
T ss_dssp             HTCCSEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------C--EEEEEECTTCH----HHHHHHHH
T ss_pred             cCCCCEEEEEeCCCCC------------hHHHHHHHHHHHHHHHcC--------C--EEEEEeCCCCH----HHHHHHHH
Confidence            4578899999997542            255677788888877642        2  23334433332    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+.. ......+...++|+|..+...+       .+..+.+.+++..
T Consensus       111 ~l~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~~~~~  163 (339)
T 3OQO_C          111 TMLG-------------------KQVDGIVFMGGNIT-DEHVAEFKRSPVPIVLAASVEE-------QEETPSVAIDYEQ  163 (339)
T ss_dssp             HHHH-------------------TTCSEEEECCSCCC-HHHHHHHTTCSSCEEEESCCCT-------TCCSCEEECCHHH
T ss_pred             HHhc-------------------CCCCEEEEcCCCCC-HHHHHHHHhCCCCEEEEcCCCC-------CCCCCEEEcCHHH
Confidence            3332                   47888887544333 3444556678999998765432       1345566677777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNYG---ESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~~---~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      .++.+++++.+.+.++++++..+....   ..+.++|++.+++. ++.+........+.+..+....+++++. ..++|+
T Consensus       164 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~d~  242 (339)
T 3OQO_C          164 AIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEA-NLPFNEQFVAEGDYTYDSGLEALQHLMSLDKKPTA  242 (339)
T ss_dssp             HHHHHHHHHHTTSCSSEEEEECCTTSHHCCCCCCHHHHHHHHTT-TCCCCGGGEEECCSCHHHHHHHHHHHHHSSSCCSE
T ss_pred             HHHHHHHHHHHCCCCcEEEEeCCCCCcccHHHHHHHHHHHHHHC-CCCcChhheecCCCChhHHHHHHHHHhhcCCCCCE
Confidence            777888888767888999998544322   45677888877764 3443211111100112233344555542 146788


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|..
T Consensus       243 i~~~~-~~~a~~~~~~l~~~g~~  264 (339)
T 3OQO_C          243 ILSAT-DEMALGIIHAAQDQGLS  264 (339)
T ss_dssp             EEESS-HHHHHHHHHHHHTTSCC
T ss_pred             EEECC-hHHHHHHHHHHHHCCCC
Confidence            87664 44556677788777763


No 210
>4RK6_A Glucose-resistance amylase regulator; sugar binding, transcription regulation, Enzyme; HET: MSE, GLC; 1.76A {Weissella paramesenteroides ATCC 33313}
Probab=97.19  E-value=5.4e-07  Score=90.02  Aligned_cols=205  Identities=10%  Similarity=0.066  Sum_probs=115.0  Template_Neff=12.100

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++.++||++.|..+.            .++.....+++.++++.|          +++.+.+...+.    +...+.
T Consensus         5 l~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~----~~~~~~   58 (287)
T 4RK6_A            5 LSSKRSRVVGVVVPLIHT------------NFADEIIKGLYETTISSG----------YELLITYLDEDE----DHQYQV   58 (287)
T ss_dssp             ------CEEEEEEESSCC------------THHHHHHHHHHHHHHHHT----------CEEEEEEECSCH----HHHHHH
T ss_pred             hhcCCCCeEEEEecCCCC------------hhHHHHHHHHHHHHHHcC----------CEEEEEECCCCH----HHHHHH
Confidence            344578899999996542            255667778887776643          233444443332    223334


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      ++++..                   ++++++|+...+... .....+...++|+|..+...+        +.++++.++.
T Consensus        59 ~~~l~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ip~v~~~~~~~--------~~~~~v~~d~  110 (287)
T 4RK6_A           59 FQTLLS-------------------RQVGAVFMLSLDIPS-WMIDKLLEEQISVISLTALLS--------EQISAVTSNE  110 (287)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSCCCH-HHHHHHHHTTCEEEEESSCCC--------TTSEEEEECH
T ss_pred             HHHHHh-------------------CCCCEEEEecCCCCH-HHHHHHHhCCCcEEEeCcccC--------CCCCEEEeCH
Confidence            444332                   478888875443332 344556677999988765332        2455666677


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL--ETPN  274 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~--~~~~  274 (908)
                      ...++.+++++.+.+.++++++..+..   ++..+.++|++.+++. +..+..........+..+....+++++  ...+
T Consensus       111 ~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~  189 (287)
T 4RK6_A          111 FEMMNSIVDYLIDMGHKNIALVGDTKLTTNISSTRRTNFIKSMTDH-NLAYENIFLYGNDHSYETGYTSVTTGYDINQLP  189 (287)
T ss_dssp             HHHHHHHHHHHHHTTCCSEEEESBCCCCSSSCCHHHHHHHHHHHHT-TCCGGGEEEECBSSCHHHHHHCCCCCSCTTSCS
T ss_pred             HHHHHHHHHHHHHCCCCcEEEEcCCccCCcccHHHHHHHHHHHHHC-CCCcceeEecCCCCChhhhhHHHHhhhhhCCCC
Confidence            777778888876667889999985432   5566778888877764 343221111110011122333344432  1236


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +++|++.. +..+..+++++++.|+.
T Consensus       190 ~~~i~~~~-~~~a~~~~~~l~~~g~~  214 (287)
T 4RK6_A          190 FTAAIATA-DMVGQGLINAMSDHGKT  214 (287)
T ss_dssp             CSEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CCEEEEcC-cHHHHHHHHHHHHcCCC
Confidence            77776654 44566778888877764


No 211
>4RK7_B Glucose-resistance amylase regulator; sugar binding, transcription regulation, Enzyme; HET: MSE, SUC; 1.8A {Weissella paramesenteroides ATCC 33313}
Probab=97.19  E-value=5.4e-07  Score=90.02  Aligned_cols=205  Identities=10%  Similarity=0.066  Sum_probs=115.0  Template_Neff=12.100

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++.++||++.|..+.            .++.....+++.++++.|          +++.+.+...+.    +...+.
T Consensus         5 l~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~----~~~~~~   58 (287)
T 4RK7_B            5 LSSKRSRVVGVVVPLIHT------------NFADEIIKGLYETTISSG----------YELLITYLDEDE----DHQYQV   58 (287)
T ss_dssp             ------CEEEEEEESSCC------------THHHHHHHHHHHHHHHTT----------CEEEEEEECSCH----HHHHHH
T ss_pred             hhcCCCCeEEEEecCCCC------------hhHHHHHHHHHHHHHHcC----------CEEEEEECCCCH----HHHHHH
Confidence            344578899999996542            255667778887776643          233444443332    223334


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      ++++..                   ++++++|+...+... .....+...++|+|..+...+        +.++++.++.
T Consensus        59 ~~~l~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ip~v~~~~~~~--------~~~~~v~~d~  110 (287)
T 4RK7_B           59 FQTLLS-------------------RQVGAVFMLSLDIPS-WMIDKLLEEQISVISLTALLS--------EQISAVTSNE  110 (287)
T ss_dssp             HHHHHT-------------------TTCSEEEECCTTCCH-HHHHHHHHTTCEEEEESSCCC--------TTSEEEEECH
T ss_pred             HHHHHh-------------------CCCCEEEEecCCCCH-HHHHHHHhCCCcEEEeCcccC--------CCCCEEEeCH
Confidence            444332                   478888875443332 344556677999988765332        2455666677


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL--ETPN  274 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~--~~~~  274 (908)
                      ...++.+++++.+.+.++++++..+..   ++..+.++|++.+++. +..+..........+..+....+++++  ...+
T Consensus       111 ~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~  189 (287)
T 4RK7_B          111 FEMMNSIVDYLIDMGHKNIALVGDTKLTTNISSTRRTNFIKSMTDH-NLAYENIFLYGNDHSYETGYTSVTTGYDINQLP  189 (287)
T ss_dssp             HHHHHHHHHHHHHTTCCSEEEESBCCCCSSSCCHHHHHHHHHHHHT-TCCGGGEEEECBSSCHHHHHHCCCCCSCTTSCS
T ss_pred             HHHHHHHHHHHHHCCCCcEEEEcCCccCCcccHHHHHHHHHHHHHC-CCCcceeEecCCCCChhhhhHHHHhhhhhCCCC
Confidence            777778888876667889999985432   5566778888877764 343221111110011122333344432  1236


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +++|++.. +..+..+++++++.|+.
T Consensus       190 ~~~i~~~~-~~~a~~~~~~l~~~g~~  214 (287)
T 4RK7_B          190 FTAAIATA-DMVGQGLINAMSDHGKT  214 (287)
T ss_dssp             CSEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CCEEEEcC-cHHHHHHHHHHHHcCCC
Confidence            77776654 44566778888877764


No 212
>4RWE_A Sugar-binding transport protein; structural genomics, The Center for; 1.65A {Yersinia pestis}
Probab=97.17  E-value=6e-07  Score=89.98  Aligned_cols=213  Identities=12%  Similarity=0.043  Sum_probs=120.4  Template_Neff=12.000

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .+.++||++.|..+.            .++.....+++.++++.|       |..+++.+.++..++.    ...+.+++
T Consensus         3 ~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~~-------g~~~~~~~~~~~~~~~----~~~~~~~~   59 (292)
T 4RWE_A            3 AELNSIGVTVGDLAN------------PFFVQITKGVELEARKLA-------GDKVKVTLVSSGYDLG----QQVAQIDN   59 (292)
T ss_dssp             -CCCEEEEEESCTTS------------HHHHHHHHHHHHHHHHHH-------CTTCEEEEEECTTCHH----HHHHHHHH
T ss_pred             cccceEEEEecccCC------------HHHHHHHHHHHHHHHHHc-------CCceEEEEecCCCCHH----HHHHHHHH
Confidence            467899999997542            256678888888888765       2345555556544322    22333443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   ++++++|+...+.. .......+...++|+|..+...+        ++.+++.+++..
T Consensus        60 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~--------~~~~~v~~d~~~  112 (292)
T 4RWE_A           60 FIA-------------------AKVDMIILNAADSKGIGPAVKRAKDAGIVVVAVDVAAE--------GADATITSDNTQ  112 (292)
T ss_dssp             HHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCEEEEESSCCT--------TCSEEEEECHHH
T ss_pred             HHH-------------------CCCCEEEEeCCCccchHHHHHHHHHCCCEEEEEcCCCC--------CCceEEecCHHH
Confidence            332                   46787776443322 22334455667999998765432        135566677777


Q NP_000836.2     202 QAQAMVDIVTALG--WNYVSTLAS-EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~--~~~v~ii~~-~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      .++.+++++.+.+  .++++++.. ...++..+.++|++.+++.+++.+....... ..+..+....++++++. .++++
T Consensus       113 ~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~  191 (292)
T 4RWE_A          113 AGAMACKYISDRLKEKGNVVIINGPPVSAIQNRVEGCESEFKKYPDIKVLSSNQNA-KGSREGGLEVMTSLLAVNPKIDG  191 (292)
T ss_dssp             HHHHHHHHHHHHTTTEEEEEEEBCCSSHHHHHHHHHHHHHHTTCTEEEEEECCCBC-TTSHHHHHHHHHHHHHHCSCCCE
T ss_pred             HHHHHHHHHHHHhCCCceEEEEeCCCChHHHHHHHHHHHHHHHCCCcEEEeeccCC-CCcHHHHHHHHHHHHHhCCCCCE
Confidence            7778888775543  778998884 3345556677788777664223332211000 01112233445555421 24566


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      |++.. +..+..+++++++.|.. ++.+++.
T Consensus       192 i~~~~-~~~a~~~~~~~~~~g~~-~~~i~~~  220 (292)
T 4RWE_A          192 VFAIN-DPTAIGADLAAKQAQRN-EFFIVGV  220 (292)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC-SSEEECS
T ss_pred             EEEcC-ChHHHHHHHHHHHcCCC-CeEEEEe
Confidence            66553 44566777788777642 3344443


No 213
>3GV0_A Transcriptional regulator, LacI family; Transcription regulator, PSI-II, 11224e, Structural; 2.35A {Agrobacterium tumefaciens str.}
Probab=97.16  E-value=6.1e-07  Score=89.81  Aligned_cols=207  Identities=8%  Similarity=0.078  Sum_probs=116.3  Template_Neff=11.800

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++.++||++.|.++..          ..++..+..+++.++++.+        ++  +.+.+...+..    .. ..+
T Consensus         4 ~~~~~~~Ig~~~~~~~~~----------~~~~~~~~~~~~~~~~~~g--------~~--~~~~~~~~~~~----~~-~~~   58 (288)
T 3GV0_A            4 RTGKTNVIALVLSVDEEL----------MGFTSQMVFGITEVLSTTQ--------YH--LVVTPHIHAKD----SM-VPI   58 (288)
T ss_dssp             ---CCCEEEEECBCCCCS----------SCHHHHHHHHHHHHHTTSS--------CE--EEECCBSSGGG----TT-HHH
T ss_pred             CCCCccEEEEEeecchHc----------ChHHHHHHHHHHHHHHhcC--------cE--EEEEecCCCcc----cc-hhH
Confidence            345689999999975321          1245667788888877642        33  33344332211    11 112


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      .+.+.                  .+++|++|+...+... .....+...++|+|.++...+       .+..+.+..++.
T Consensus        59 ~~~~~------------------~~~~d~ii~~~~~~~~-~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~  112 (288)
T 3GV0_A           59 RYILE------------------TGSADGVIISKIEPND-PRVRFMTERNMPFVTHGRSDM-------GIEHAFHDFDNE  112 (288)
T ss_dssp             HHHHH------------------HTCCSEEEEESCCTTC-HHHHHHHHTTCCEEEESCCCS-------SCCCEEEEECHH
T ss_pred             HHHHH------------------hCCCCEEEEeCCCCCC-HHHHHHHHcCCCEEEeCCCCC-------CCCCcEEecCcH
Confidence            22111                  1578888876544333 444556678999998776432       123455666666


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGNY--GESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~~--~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      ..++.+++++.+.+.++++++..+..+  ...+.++|++.+++. ++.+........+.+..+....+++++. ..++|+
T Consensus       113 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~d~  191 (288)
T 3GV0_A          113 AYAYEAVERLAQCGRKRIAVIVPPSRFSFHDHARKGFNRGIRDF-GLTEFPIDAVTIETPLEKIRDFGQRLMQSSDRPDG  191 (288)
T ss_dssp             HHHHHHHHHHHHTTCCEEEEECCCTTSHHHHHHHHHHHHHHHHT-TCEECCCCSCCTTSCHHHHHHHHHHHTTSSSCCSE
T ss_pred             HHHHHHHHHHHHCCCCeEEEECCCCCCchHHHHHHHHHHHHHHc-CCCCCCceeEEeCCCHHHHHHHHHHHHccCCCCCE
Confidence            677778888766788899999864433  445677888877764 3433221001100111233344555532 236788


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|..
T Consensus       192 i~~~~-~~~a~~~~~~l~~~g~~  213 (288)
T 3GV0_A          192 IVSIS-GSSTIALVAGFEAAGVK  213 (288)
T ss_dssp             EEESC-HHHHHHHHHHHHTTTCC
T ss_pred             EEEcC-HHHHHHHHHHHHHcCCC
Confidence            77664 44566778888877764


No 214
>5HKO_A ABC transporter, carbohydrate uptake transporter-2; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: ACT, 62W, IMD, ZN; 1.2A {Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)}
Probab=97.16  E-value=6.3e-07  Score=92.68  Aligned_cols=214  Identities=13%  Similarity=0.076  Sum_probs=118.8  Template_Neff=10.600

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++.++||++.|...             .++.....+++.++++.+          +++.+.|...+..    ...+.
T Consensus        28 ~~~~~~~~Ig~v~~~~~-------------~~~~~~~~g~~~a~~~~g----------~~l~~~~~~~~~~----~~~~~   80 (348)
T 5HKO_A           28 AANSDTKRIGVTVYDMS-------------SFITEGKEGMDTYAKANN----------IELVWNSANNDVS----TQASQ   80 (348)
T ss_dssp             -----CEEEEEEESCCC-------------HHHHHHHHHHHHHHHHTT----------EEEEEEECTTCHH----HHHHH
T ss_pred             cccCCCcEEEEEECCCC-------------HHHHHHHHHHHHHHHHCC----------CEEEEecCCCCHH----HHHHH
Confidence            45567899999998652             245566777777776642          3444555443321    22233


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   .+++++|....+.. .......+...++|+|..+...+.      .++++++.++
T Consensus        81 i~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d  135 (348)
T 5HKO_A           81 VDSLIN-------------------QGVDAIIVVPVQADSLGPQVASAKSKGIPLLAVNAALET------PDLAGNVQPD  135 (348)
T ss_dssp             HHHHHH-------------------TTCSEEEEECSCSSCCHHHHHHHHHTTCCEEEESSCCCC------TTCSEEEEEC
T ss_pred             HHHHHH-------------------CCCCEEEEeCCCccccHHHHHHHHHCCCCEEEEcCCCCC------CCCceEEcCC
Confidence            343332                   46787776443322 223445566789999987654321      2345677777


Q NP_000836.2     199 DSYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET--  272 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--  272 (908)
                      +...++.+++++.+.  +.++++++..  ++.+...+.++|++.+++.+++.+.......  .+..+....+++++..  
T Consensus       136 ~~~~g~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~  213 (348)
T 5HKO_A          136 DVAAGAQEMQMMADRLGGKGNIVILQGPLGGSGEINRGKGIDQVLAKYPDIKVLAKDTAN--WKRDEAVNKMKNWISSFG  213 (348)
T ss_dssp             HHHHHHHHHHHHHHHHTTCEEEEEEECSTTSHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHHG
T ss_pred             HHHHHHHHHHHHHHHhCCCcEEEEEECCCCChHHHHHHHHHHHHHHhCCCcEEEEeecCC--CCHHHHHHHHHHHHHHhC
Confidence            777777888877544  6788999885  3345566777888877663223332111111  1112333445555421  


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSD  309 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~  309 (908)
                      .++|+|++.. +..+..+++++++.|.. ++.+++.+
T Consensus       214 ~~~d~I~~~~-d~~a~~~~~al~~~g~~-~i~iig~d  248 (348)
T 5HKO_A          214 PQIDGVVAQN-DDMGLGALQALKEAGRT-GVPIVGID  248 (348)
T ss_dssp             GGCCEEEESS-HHHHHHHHHHHHHTTCC-SCCEECSB
T ss_pred             CCCCEEEECC-hHHHHHHHHHHHHcCCC-CCCEEEec
Confidence            2477777664 44566778888877763 33444443


No 215
>4RXU_A Periplasmic sugar-binding protein; SUGAR TRANSPORTER, ABC-TYPE, ENZYME FUNCTION; HET: BGC, CIT; 1.4A {Chloroflexus aurantiacus}
Probab=97.15  E-value=6.5e-07  Score=93.42  Aligned_cols=153  Identities=17%  Similarity=0.075  Sum_probs=91.9  Template_Neff=10.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      ....++.++||++.|..+.            .++..+..+++.++++.|          +++.+.|...+.    +...+
T Consensus        24 ~~~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~a~~~~g----------~~l~~~~~~~~~----~~~~~   77 (367)
T 4RXU_A           24 STGNTQQLAVGIVLPTKDE------------PRWIQDETRFREALQQAG----------YQVEILFSQGSS----AKEKE   77 (367)
T ss_dssp             ----CEEEEEEEEESCSSS------------THHHHHHHHHHHHHHHHT----------EEEEEEECTTCH----HHHHH
T ss_pred             CCCCCCCeEEEEEeCCCCC------------hHHHhHHHHHHHHHHHcC----------CEEEEEecCCCH----HHHHH
Confidence            3456678999999997542            255677788888887753          344445544332    22333


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGA-AASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~-~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   ++++++|.. ..+.........+...++|+|..+...+.     ..++.+++.+
T Consensus        78 ~i~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvi~~~~~~~~-----~~~~~~~v~~  133 (367)
T 4RXU_A           78 NVEALIA-------------------KGIKVLIICPHDGTAAAAAAEAARAAGVKVISYDRLIRE-----TDAVDYYVTF  133 (367)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCEEEEESSCCCS-----CSCCCEEEEE
T ss_pred             HHHHHHH-------------------cCCCEEEEcCCChhHHHHHHHHHHHCCCEEEEecCCCCC-----CCCccEEEEc
Confidence            3444332                   467766643 33333334455567789999987764432     1244567777


Q NP_000836.2     198 PDSYQAQAMVDIVTAL--GWNYVSTLA---SEGNYGESGVEAFTQISRE  241 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~--~~~~v~ii~---~~~~~~~~~~~~~~~~~~~  241 (908)
                      ++...++.+++++.+.  +.++++++.   .++.+...+.++|++.+++
T Consensus       134 d~~~~g~~~~~~l~~~~~g~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~  182 (367)
T 4RXU_A          134 DSIAVGAQQAQYLVDHASGTGNPLYLYAGAASDNNAFLFFEGAWKVLQP  182 (367)
T ss_dssp             CHHHHHHHHHHHHHHTCCSSCEEEEECBCCTTSHHHHHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHHccCCCCcEEEEecCCCChhHHHHHHHHHHHHHH
Confidence            7777788888887654  778899886   2334555666677666654


No 216
>4KMR_A Transcriptional regulator, LacI family; Structural Genomics, PSI-Biology, Midwest Center; 1.45A {Sanguibacter keddieii}
Probab=97.14  E-value=6.7e-07  Score=88.91  Aligned_cols=201  Identities=12%  Similarity=0.072  Sum_probs=113.6  Template_Neff=12.100

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      +..+||++.|..+.            .++.....+++.++++.|          +.+.+.|+..++.    ...+.++++
T Consensus         2 ~~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~~~   55 (280)
T 4KMR_A            2 RSGVIGLAVPELGQ------------AFFAQLADEVIRVAAEQD----------LVVLVEQTGGLRE----RELEALRNP   55 (280)
T ss_dssp             CCSEEEEEESCTTS------------HHHHHHHHHHHHHHHTTT----------CEEEEEECTTCHH----HHHHHHHCG
T ss_pred             CcceEEEEeCccch------------HHHHHHHHHHHHHHHHCC----------CEEEEEecCCchH----HHHHHHHhh
Confidence            46789999987542            256678888888887763          2334445433321    222333333


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      +.                   +++|++|+...+.....  ..+...++|+|..+...+       .++.+.+.+++...+
T Consensus        56 ~~-------------------~~~d~ii~~~~~~~~~~--~~~~~~~ip~v~~~~~~~-------~~~~~~v~~d~~~~~  107 (280)
T 4KMR_A           56 RL-------------------SLTDGLLLAPLGLTQDD--VLPDPAGRPLVVLGEPLF-------PGPVDHVTMQHEAAA  107 (280)
T ss_dssp             GG-------------------TTCSCEEECCSSCC-CC--C------CCEEEESSSCC-------CSSCEEECCCHHHHH
T ss_pred             HH-------------------hcCCEEEEecCCCCCcc--cCcCcCCCcEEEECCCCC-------CCCCCEEEcCHHHHH
Confidence            32                   47888876544332221  234678999998776432       134566677777777


Q NP_000836.2     204 QAMVDIVTALGWNYVSTLASEG----NYGESGVEAFTQISREIGGVCIAQSQKIP-REPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       204 ~~~~~~l~~~~~~~v~ii~~~~----~~~~~~~~~~~~~~~~~~~i~v~~~~~~~-~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      +.+++++.+.+.++++++..+.    .++..+.+++++.+++. ++.+.....+. ...+..+....++++++ ..++++
T Consensus       108 ~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  186 (280)
T 4KMR_A          108 RAATEHLLGLGRRRVMLLGAHATERTGVAALRYAGYREALTAA-GLAVDDDLVVPVETWDRSSGAEAMARVLDAGVRMDA  186 (280)
T ss_dssp             HHHHHHHHHTTCCCEEEETSCSSCCCHHHHHHHHHHHHHHHHT-TCCCCGGGEECCSSCSHHHHHHHHHHHHHTTCCCSE
T ss_pred             HHHHHHHHHCCCCeEEEEecCcccCchhHHHHHHHHHHHHHHc-CCCCCCCeEeecCCCChhHHHHHHHHHHHcCCCCCE
Confidence            7888888767889999998543    35566778888888765 34433211111 00111223344455442 135777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       187 i~~~~-~~~a~~~~~~~~~~g~~  208 (280)
T 4KMR_A          187 VFAMN-DDLALGALRSLQERGVA  208 (280)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            77664 44566778888877764


No 217
>3L6U_A ABC-TYPE SUGAR TRANSPORT SYSTEM PERIPLASMIC; structural genomics, NYSGRC, target 11006s; HET: MSE, SO4; 1.9A {Exiguobacterium sibiricum}
Probab=97.14  E-value=6.8e-07  Score=89.71  Aligned_cols=205  Identities=11%  Similarity=0.062  Sum_probs=114.7  Template_Neff=11.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|..+.            .++.....+++.++++.+          +++.+.+...++.    ...+.++
T Consensus         5 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~~----~~~~~~~   58 (293)
T 3L6U_A            5 SPKRNIVGFTIVNDKH------------EFAQRLINAFKAEAKANK----------YEALVATSQNSRI----SEREQIL   58 (293)
T ss_dssp             ----CEEEEEESCSCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECSSCHH----HHHHHHH
T ss_pred             CCCCcEEEEEECCCCC------------HHHHHHHHHHHHHHHHCC----------CeEEEecCCCCHH----HHHHHHH
Confidence            4567899999987542            245667788888877652          2344444433321    2223333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   +++|++|+...+... ......+...++|+|..+...+.      .++++++.+++.
T Consensus        59 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  113 (293)
T 3L6U_A           59 EFVH-------------------LKVDAIFITTLDDVYIGSAIEEAKKAGIPVFAIDRMIRS------DAVVSSITSNNQ  113 (293)
T ss_dssp             HHHH-------------------TTCSEEEEECSCTTTTHHHHHHHHHTTCCEEEESSCCCC------TTCSEEEEECHH
T ss_pred             HHHh-------------------cCCCEEEEecCCcchHHHHHHHHHHcCCCEEEEcCCCCC------CccceEEecChH
Confidence            3332                   478888765433322 24445566789999987654321      245667777777


Q NP_000836.2     201 YQAQAMVDIVTAL-------GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       201 ~~~~~~~~~l~~~-------~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      ..++.+++++.+.       +.++++++..  +..++..+.+++++.+++.+.+.+.......  .+..+....++++++
T Consensus       114 ~~~~~~~~~l~~~~~~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~  191 (293)
T 3L6U_A          114 MIGEQLASYIKNELIKQTGRSTGRIVEITGTANVYTTNERHRGFLKGIENEPTLSIVDSVSGN--YDPVTSERVMRQVID  191 (293)
T ss_dssp             HHHHHHHHHHHHHHHHHHSCSCEEEEEEECSTTCHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHhCCCceEEEEEEcCCCChhHHHHHHHHHHHHHhCCCceEEeeeeCC--CCHHHHHHHHHHHHH
Confidence            7777777776432       4578988875  3345666777888877664222332111111  111223344455542


Q NP_000836.2     272 T-PNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 ~-~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      . .++++|++.. +..+..+++++++.|+.
T Consensus       192 ~~~~~~~i~~~~-~~~a~~~~~al~~~g~~  220 (293)
T 3L6U_A          192 SGIPFDAVYCHN-DDIAMGVLEALKKAKIS  220 (293)
T ss_dssp             TTCCCSEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             hCCCCCEEEECC-hHHHHHHHHHHHHCCCC
Confidence            1 2477777664 44566778888877764


No 218
>2DRI_A D-RIBOSE-BINDING PROTEIN COMPLEXED WITH BETA-D-RIBOSE; SUGAR TRANSPORT; HET: RIP; 1.6A {Escherichia coli} SCOP: c.93.1.1
Probab=97.14  E-value=6.8e-07  Score=88.20  Aligned_cols=207  Identities=14%  Similarity=0.114  Sum_probs=116.2  Template_Neff=12.400

Q NP_000836.2      46 IILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALIE  125 (908)
Q Consensus        46 i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~~  125 (908)
                      .+||++.|..+.            ..+.....+++.++++.|          +++.+.|+..+..    ...+.++++..
T Consensus         2 ~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~~~~~   55 (271)
T 2DRI_A            2 DTIALVVSTLNN------------PFFVSLKDGAQKEADKLG----------YNLVVLDSQNNPA----KELANVQDLTV   55 (271)
T ss_dssp             CEEEEEESCSSS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCHH----HHHHHHHHHTT
T ss_pred             CeEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCHH----HHHHHHHHHHH
Confidence            478888887542            255677788888887753          3344455433321    22233333332


Q NP_000836.2     126 KDASDVKCANGDPPIFTKPDKISGVI-GAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       126 ~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                                         +++++++ ++..+.........+.+.++|+|..+...+.      .++++++.+++...++
T Consensus        56 -------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~------~~~~~~v~~d~~~~~~  110 (271)
T 2DRI_A           56 -------------------RGTKILLINPTDSDAVGNAVKMANQANIPVITLDRQATK------GEVVSHIASDNVLGGK  110 (271)
T ss_dssp             -------------------TTEEEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCSS------SCCSEEEEECHHHHHH
T ss_pred             -------------------CCCCEEEEecCCcchHHHHHHHHHHCCCCEEEEcCCCCC------CceEEEEEeCcHHHHH
Confidence                               3566554 4433333334445567789999987754321      2456777777777788


Q NP_000836.2     205 AMVDIVTALGW--NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAVI  279 (908)
Q Consensus       205 ~~~~~l~~~~~--~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~viv  279 (908)
                      .+++++.+.+.  .+++++..  +..++..+.+++++.+++. ++++.......  .+..+....+++++.. .++++|+
T Consensus       111 ~~~~~l~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~~i~  187 (271)
T 2DRI_A          111 IAGDYIAKKAGEGAKVIELQGIAGTSAARERGEGFQQAVAAH-KFNVLASQPAD--FDRIKGLNVMQNLLTAHPDVQAVF  187 (271)
T ss_dssp             HHHHHHHHHHCTTCEEEEEECCTTCHHHHHHHHHHHHHHHHH-TCEEEEEEECT--TCHHHHHHHHHHHHHHCTTCCEEE
T ss_pred             HHHHHHHHHhCCCceEEEEEcCCCChhHHHHHHHHHHHHHhc-CceEEEeecCC--CcHHHHHHHHHHHHHHCCCCCEEE
Confidence            88888755432  35666652  3445667778888888775 35543221111  1122344445555421 2477776


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +.. +..+..+++++++.|.. ++.+++.
T Consensus       188 ~~~-~~~~~~~~~~~~~~g~~-~~~i~~~  214 (271)
T 2DRI_A          188 AQN-DEMALGALRALQTAGKS-DVMVVGF  214 (271)
T ss_dssp             ESS-HHHHHHHHHHHHHHTCC-SCEEEEE
T ss_pred             eCC-HHHHHHHHHHHHHcCCC-CcEEEEe
Confidence            654 34466777888777652 3344443


No 219
>3D02_A Putative LACI-type transcriptional regulator; YP_001338366.1, periplasmic sugar-binding protein, Structural; HET: GOL; 1.3A {Klebsiella pneumoniae subsp. pneumoniae}
Probab=97.14  E-value=6.9e-07  Score=90.14  Aligned_cols=214  Identities=13%  Similarity=0.071  Sum_probs=117.2  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .++++||++.|..+.            .++.....+++.++++++        +++.+. .+...++    ....+.+++
T Consensus         2 ~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~-~~~~~~~----~~~~~~~~~   56 (303)
T 3D02_A            2 AAEKTVVNISKVDGM------------PWFNRMGEGVVQAGKEFN--------LNASQV-GPSSTDA----PQQVKIIED   56 (303)
T ss_dssp             --CEEEEEECSCSSC------------HHHHHHHHHHHHHHHHTT--------EEEEEE-CCSSSCH----HHHHHHHHH
T ss_pred             CCceEEEEEeCCCCC------------hHHHHHHHHHHHHHHHcC--------CEEEEe-CCCCCCH----HHHHHHHHH
Confidence            357899999997542            255677888888888763        344443 2332332    223334444


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGA-AASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~-~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   ++++++|+. ..+.........+...++|+|......+.      .++++++..+...
T Consensus        57 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~~~~~~~~  111 (303)
T 3D02_A           57 LIA-------------------RKVDAITIVPNDANVLEPVFKKARDAGIVVLTNESPGQP------SANWDVEIIDNEK  111 (303)
T ss_dssp             HHH-------------------TTCSEEEECCSCHHHHHHHHHHHHHTTCEEEEESCTTCT------TCSEEEESSCHHH
T ss_pred             HHH-------------------CCCCEEEECCCCccchHHHHHHHHHCCCEEEEeCCCCCC------ccceeEeeeChHH
Confidence            332                   467877753 33333334455566789999987654321      2345556666666


Q NP_000836.2     202 QAQAMVDIVTA-LGW-NYVSTLAS--EGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLET-PNA  275 (908)
Q Consensus       202 ~~~~~~~~l~~-~~~-~~v~ii~~--~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~  275 (908)
                      .+..+++++.+ .+. ++++++..  ++.++..+.++|++.+++.+ ++++.... .....+..+....+++++.. .++
T Consensus       112 ~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~  190 (303)
T 3D02_A          112 FAAEYVEHMAKRMGGKGGYVIYVGSLTVPQHNLWADLLVKYQKEHYPDMHEVTRR-MPVAESVDDSRRTTLDLMKTYPDL  190 (303)
T ss_dssp             HHHHHHHHHHHHTTTCEEEEEECSCSSCHHHHHHHHHHHHHHHHHCTTEEESSSC-BSCTTCHHHHHHHHHHHHHHCTTE
T ss_pred             HHHHHHHHHHHHhCCCeeEEEEECCCCChhHHHHHHHHHHHHHHHCCCceEeecc-CCCCCCHHHHHHHHHHHHHHCCCc
Confidence            67777777654 366 68998875  33455667778877776531 23332211 01001112333445555421 245


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|++.. +..+..+++++++.|...++.+++.
T Consensus       191 ~~i~~~~-~~~a~~~~~a~~~~g~~~~~~v~~~  222 (303)
T 3D02_A          191 KAVVSFG-SNGPIGAGRAVKEKRAKNKVAVYGM  222 (303)
T ss_dssp             EEEEESS-TTHHHHHHHHHHHTTCTTTCEEEEC
T ss_pred             cEEEEeC-CCchHHHHHHHHHhccCCCeEEEEe
Confidence            6665543 4455668888888776323444443


No 220
>4WZZ_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: RAM, EDO, MSE; 1.7A {Clostridium phytofermentans}
Probab=97.13  E-value=7.2e-07  Score=93.23  Aligned_cols=215  Identities=11%  Similarity=0.034  Sum_probs=119.6  Template_Neff=11.000

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC-SRDTYALEQSLTF  119 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~-~~~~~a~~~~~~~  119 (908)
                      ...++++||++.|..+.            .++..+..+++.++++.+        +  ++.+.+.. .+.    +...+.
T Consensus        50 ~~~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~l~~~~~~~~~~----~~~~~~  103 (371)
T 4WZZ_A           50 GYATTATYAIIVKSAGN------------PYNQKESEGYKQVIEANG--------G--KCVIQEPKSATA----EDQITC  103 (371)
T ss_dssp             -CCCCCEEEEECSCSSC------------HHHHHHHHHHHHHHHHTT--------C--EEEEECCSSSSH----HHHHHH
T ss_pred             CCCCCcEEEEEEcCCCC------------HHHHHHHHHHHHHHHHcC--------C--EEEEECCCCCCH----HHHHHH
Confidence            35678999999987542            255677788888887752        3  33344433 232    233344


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGA-AASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~-~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   +++|++|+. ..+.........+...++|+|..+...+.     ..++.+....+
T Consensus       104 ~~~li~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~v~~~~  159 (371)
T 4WZZ_A          104 INNAIS-------------------QGVDCIAIAANDTDALEPALTEAKNQGIHVLSLDSATNA-----NSRKVFVNQAG  159 (371)
T ss_dssp             HHHHHH-------------------HTCSEEEECCSSSSTTHHHHHHHHHTTCEEEEESSCCCG-----GGCSCEEESSC
T ss_pred             HHHHHH-------------------cCCCEEEEcCCCHHhHHHHHHHHHHCCCEEEEECCCCCc-----cccceEEeccC
Confidence            444432                   478888764 33333334455667789999987764432     12233444334


Q NP_000836.2     199 DSYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREI--GGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~--~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      ....++.+++++.+.  +.++++++..  ++.+...+.++|++.+++.  .++++.......  .+..+....++++++.
T Consensus       160 ~~~~~~~~~~~l~~~~~g~~~v~~l~~~~~~~~~~~r~~g~~~~~~~~~~~~~~v~~~~~~~--~~~~~~~~~~~~~l~~  237 (371)
T 4WZZ_A          160 TTQIAQALMDAILDISGGSGDWAVLSAASTATNQNAWIDGMKTVMQDSKYSKLNLIGVYYGD--DEYQASCDQTEAILAA  237 (371)
T ss_dssp             HHHHHHHHHHHHHHHTTSCEEEEEEESCTTCHHHHHHHHHHHHHTTSGGGTTEEEEEEEECT--TCHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHhCCCeeEEEEECCCCcHhHHHHHHHHHHHHhhccCCCcEEEEEecCC--CCHHHHHHHHHHHHHH
Confidence            555677777777553  5678998873  3445667778888877642  124433221111  1122344455555431


Q NP_000836.2     273 -PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       273 -~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                       .+.++|+.. ++..+..+++++++.|+..++.+++.
T Consensus       238 ~~~~~~i~~~-~~~~a~~~~~al~~~g~~~~v~v~~~  273 (371)
T 4WZZ_A          238 DPNIKVICAP-TTVGIMAAAKVLQDKGLSGKVKLTGL  273 (371)
T ss_dssp             CTTCCEEEEC-SHHHHHHHHHHHHHTTCTTTSEEEEB
T ss_pred             CCCCCEEEeC-CchHHHHHHHHHHHCCCCCCeEEEec
Confidence             234555443 34456677888888776323444443


No 221
>1JX6_A LUXP PROTEIN; PROTEIN-LIGAND COMPLEX, SIGNALING PROTEIN; HET: AI2; 1.5A {Vibrio harveyi} SCOP: c.93.1.1
Probab=97.13  E-value=7.2e-07  Score=91.91  Aligned_cols=222  Identities=11%  Similarity=0.029  Sum_probs=124.3  Template_Neff=11.600

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+..           .+......+++.++++.+.      .+.+++.+.|+..++.    ...+.++
T Consensus        40 ~~~~~~Igvv~~~~~~~-----------~~~~~~~~g~~~~~~~~g~------~~~~~~~~~d~~~~~~----~~~~~~~   98 (342)
T 1JX6_A           40 TQRPIKISVVYPGQQVS-----------DYWVRNIASFEKRLYKLNI------NYQLNQVFTRPNADIK----QQSLSLM   98 (342)
T ss_dssp             CSSCEEEEEEECCCSSC-----------CHHHHHHHHHHHHHHHTTC------CEEEEEEECCTTCCHH----HHHHHHH
T ss_pred             CCCCEEEEEEecCCCCC-----------HHHHHHHHHHHHHHHHcCC------eEEEEEEecCCCCCHH----HHHHHHH
Confidence            56789999999975321           1334778888888887642      1223334556544422    2333444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRL-FKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~-~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   ++++++|+...+.........+.. .++|+|..+...+.... ...++++++.+++.
T Consensus        99 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~-~~~~~~~~v~~d~~  158 (342)
T 1JX6_A           99 EALK-------------------SKSDYLIFTLDTTRHRKFVEHVLDSTNTKLILQNITTPVREW-DKHQPFLYVGFDHA  158 (342)
T ss_dssp             HHHH-------------------TTCSEEEECCSSSTTHHHHHHHHHHCSCEEEEETCCSCBGGG-TTSCCSEEEECCHH
T ss_pred             HHHh-------------------cCCCEEEEeCCchHHHHHHHHHHHhCCCeEEEEeCCCCcchh-cCCCCeEEEEcChH
Confidence            4432                   478888876533332333444443 78999987654432111 01356777888887


Q NP_000836.2     201 YQAQAMVDIVTALGWN--YVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~--~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~  276 (908)
                      ..+..+++++.+.+.+  +++++... +.++..+.+++++.+++.+++++.......  .+..+....+++++.. .+++
T Consensus       159 ~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~~  236 (342)
T 1JX6_A          159 EGSRELATEFGKFFPKHTYYSVLYFSEGYISDVRGDTFIHQVNRDNNFELQSAYYTK--ATKQSGYDAAKASLAKHPDVD  236 (342)
T ss_dssp             HHHHHHHHHHHHHSCTTCEEEEECCSTTHHCCCCCCHHHHHHHHHHCCEEEEEECCC--SSHHHHHHHHHHHHHHCCCCS
T ss_pred             HHHHHHHHHHHHhcCCCCeEEEEEecCCcchHHHHHHHHHHHHhcCCceEEeeeccC--CCHHHHHHHHHHHHHHCCCCC
Confidence            7888888887654443  48888754 445667777888877653223332211111  1122344455555421 2455


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +|+.. ++..+..+++++++.|. .++.+++.
T Consensus       237 ~i~~~-~~~~a~~~~~~~~~~g~-~~~~v~~~  266 (342)
T 1JX6_A          237 FIYAC-STDVALGAVDALAELGR-EDIMINGW  266 (342)
T ss_dssp             EEEES-SHHHHHHHHHHHHHHTC-TTSEEBCS
T ss_pred             EEEEC-CHHHHHHHHHHHHHcCC-CCcEEEee
Confidence            55554 34455667888887776 23344443


No 222
>4WT7_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; Enzyme Function Initiative, EFI, Structural; HET: X9X; 2.0A {Agrobacterium vitis S4}
Probab=97.12  E-value=7.7e-07  Score=90.79  Aligned_cols=202  Identities=10%  Similarity=-0.005  Sum_probs=116.3  Template_Neff=11.400

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..++++||++.|.++.            .+......+++.++++.          .+++.+.|+..++.    ...+.++
T Consensus        29 ~~~~~~Ig~v~~~~~~------------~~~~~~~~~~~~a~~~~----------~~~l~~~~~~~~~~----~~~~~~~   82 (321)
T 4WT7_A           29 SLKGKRIGISTAGTDH------------FFDLQAYNAQIAEVKRL----------GGEPLAVDAGRSDG----KLVAQLQ   82 (321)
T ss_dssp             CCTTCEEEEEESCCSS------------HHHHHHHHHHHHHHHHT----------TCEEEEEECTTCHH----HHHHHHH
T ss_pred             hcCCcEEEEEcCCCCc------------HHHHHHHHHHHHHHHHc----------CCeEEEEeCCCCHH----HHHHHHH
Confidence            4478999999997532            12334556666666543          24455556544322    2333444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAA-ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   ++++++|... .+.........+.+.++|+|..+...+        ++++++.+++.
T Consensus        83 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~--------~~~~~v~~d~~  135 (321)
T 4WT7_A           83 TLIA-------------------QKPDAIVQLLGTLTVIDPWLKRARDAGIPVLTIDVGSS--------HSLNNSTSDNW  135 (321)
T ss_dssp             HHHH-------------------HCCSEEEEECCCHHHHHHHHHHHHHTTCCEEEESCCCT--------TCSCEEECCHH
T ss_pred             HHHH-------------------CCCCEEEEcCCChhhhHHHHHHHHHcCCCEEEECCCCC--------CcceeecCChH
Confidence            4332                   4677766543 333333445566778999998765432        34667777777


Q NP_000836.2     201 YQAQAMVDIVTA--LGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQ--KIPREPRPGEFEKIIKRLLETPN  274 (908)
Q Consensus       201 ~~~~~~~~~l~~--~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~--~~~~~~~~~~~~~~~~~l~~~~~  274 (908)
                      ..++.+++++.+  .+.++++++..  +..++..+.++|++.+++.+++++....  ... ..+..+....++++++ .+
T Consensus       136 ~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~-~~  213 (321)
T 4WT7_A          136 GIGKDLALQLVSDIGGEGNVVVFNGFYGVTPCAIRYDQLVNVIKYFPKVKIIQPELRDVI-PNTVQDAFAQVTAILN-KY  213 (321)
T ss_dssp             HHHHHHHHHHHHHTTTCEEEEEECCCTTSHHHHHHHHHHHHHHTTSTTEEECSSCBCCCS-SSHHHHHHHHHHHHHH-HS
T ss_pred             HHHHHHHHHHHHHhCCCceEEEEEcCCCCCcHHHHHHHHHHHHHHCCCcEEEcccccCCC-CCCHHHHHHHHHHHHH-HC
Confidence            777777777755  47788999985  4456667788888877653213332210  010 0112234445555553 23


Q NP_000836.2     275 -----ARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       275 -----~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                           +++|++.. +..+..+++++++.|.
T Consensus       214 ~~~~~~~~i~~~~-~~~a~~~~~~l~~~g~  242 (321)
T 4WT7_A          214 PEKGSIKAIWSAW-DIPQLGATQALAAAGR  242 (321)
T ss_dssp             CSTTSCCEEEESS-HHHHHHHHHHHHHHTC
T ss_pred             CCcCCccEEEeCC-ChhHHHHHHHHHHCCC
Confidence                 56666553 4556678888887776


No 223
>2RJO_A Twin-arginine translocation pathway signal protein; PSI-2, NYSGXRC, twin arginine translocation; HET: SO4, GAL; 2.05A {Burkholderia phytofirmans}
Probab=97.09  E-value=8.7e-07  Score=90.86  Aligned_cols=217  Identities=10%  Similarity=0.034  Sum_probs=119.1  Template_Neff=11.400

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||++.|..+.            .++..+..+++.++++.|          +++.+.|+..++.    ...+.+++
T Consensus         3 ~~~~~Igvv~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~~   56 (332)
T 2RJO_A            3 LGQTTLACSFRSLTN------------PYYTAFNKGAQSFAKSVG----------LPYVPLTTEGSSE----KGIADIRA   56 (332)
T ss_dssp             CCCCEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT----------CCEEEEECTTCHH----HHHHHHHH
T ss_pred             CCccEEEEEEcCCCC------------HHHHHHHHHHHHHHHHcC----------CCEEEeeCCCCHH----HHHHHHHH
Confidence            467899999997542            255677788888887753          3344455443322    22333443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIG---AAASSVSIMVANILRLFKIPQISYASTAPELSDN-TRYDFFSRVVPP  198 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg---~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~-~~~~~~~~~~~~  198 (908)
                      ++.                   +++++++.   +..+.........+...++|+|..+...+..... ...++++++..+
T Consensus        57 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~~~~~~~~~~~v~~d  117 (332)
T 2RJO_A           57 LLQ-------------------KTGGNLVLNVDPNDSADARVIVEACSKAGAYVTTIWNKPKDLHPWDYNPNYVAHLSYD  117 (332)
T ss_dssp             HHH-------------------HTTTCEEEEECCSSHHHHHHHHHHHHHHTCEEEEESCCCTTCCGGGGTTTEEEEEECC
T ss_pred             HHh-------------------cCCCEEEEEcCCCCcchHHHHHHHHHHcCCEEEEEcCCCCCCCcccCCCCceEEEecC
Confidence            332                   34565553   3222222334455667899999876544321100 012456677777


Q NP_000836.2     199 DSYQAQAMVDIVT-ALGWN-YVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET--  272 (908)
Q Consensus       199 ~~~~~~~~~~~l~-~~~~~-~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--  272 (908)
                      +...+..+++++. +.+.+ +++++..  +...+..+.++|++.+++..++.+.......  .+..+....++++++.  
T Consensus       118 ~~~~~~~~~~~l~~~~g~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~  195 (332)
T 2RJO_A          118 GVAYGEETATQLFKSMGGKGGVVALGGIFSNVPAIERKAGLDAALKKFPGIQLLDFQVAD--WNSQKAFPIMQAWMTRFN  195 (332)
T ss_dssp             HHHHHHHHHHHHHHHTTTCEEEEEEECCTTCHHHHHHHHHHHHHHHTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHHG
T ss_pred             hHHHHHHHHHHHHHHcCCCeEEEEEeCCCCCHHHHHHHHHHHHHHHhCCCcEEeeeEeCC--CCHHHHHHHHHHHHHHcc
Confidence            7666777777764 45665 8998853  3345666777888877653124443211111  1112233445555421  


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIG  307 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~  307 (908)
                      .++++|++.. +..+..+++++++.|+..++.+++
T Consensus       196 ~~~d~i~~~~-~~~a~~~~~a~~~~g~~~~~~i~~  229 (332)
T 2RJO_A          196 SKIKGVWAAN-DDMALGAIEALRAEGLAGQIPVTG  229 (332)
T ss_dssp             GGEEEEEESS-HHHHHHHHHHHHHTTCBTTBCEEC
T ss_pred             CccCEEEECC-HHHHHHHHHHHHHCCCCCCCCEEc
Confidence            2567776654 445567778888777632333333


No 224
>4Y9T_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: MSE, PA1; 1.801A {Agrobacterium vitis}
Probab=97.09  E-value=8.9e-07  Score=91.44  Aligned_cols=205  Identities=12%  Similarity=0.072  Sum_probs=115.5  Template_Neff=11.000

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++..+..+++.++++.|          +++.+.|...+..    ...+.++
T Consensus        24 ~~~~~~Igvi~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~l~~~~~~~~~~----~~~~~~~   77 (346)
T 4Y9T_A           24 AQTKGMVYYLVPTLLD------------EFQTGSVNALSMFLGQVG----------YEMKTLNADNKTD----AQQSQMN   77 (346)
T ss_dssp             --CCCEEEEEESCCCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCHH----HHHHHHH
T ss_pred             cCCCCEEEEEccCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEeCCCCHH----HHHHHHH
Confidence            3478999999987642            255677788888777653          3444555443322    2333344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASS-VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~-~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   +++|++|+...+. ........+...++|+|..+...+.      .++.+++.++..
T Consensus        78 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  132 (346)
T 4Y9T_A           78 DVIA-------------------LKPAAIILAAVDFNALKPSIEAARAAGIPVVEFDRQITS------TPSDFTSVAGTV  132 (346)
T ss_dssp             HHHH-------------------HCCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCCS------SCCSEEEEECHH
T ss_pred             HHHh-------------------cCCCEEEEcCCCccchHHHHHHHHHCCCCEEEeCCCCCC------CCCceEEEeChH
Confidence            4332                   4678777644332 2224445566789999987764331      134556666666


Q NP_000836.2     201 YQAQAMVDIVTALGW-------NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~-------~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      ..++.+++++.+.+.       ++++++..  +..++..+.++|++.+++..++.+.......  .+..+....++++++
T Consensus       133 ~~~~~~~~~l~~~~~~~~~~~~~~i~~i~~~~~~~~~~~r~~g~~~~l~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~  210 (346)
T 4Y9T_A          133 EIGHIAGDHAISLLKGKNGDVKGKILQVPGDPGDPYTLDIQKGFEEKIKAFPGVKIISVPAVQ--WEASAAGTIVSDQML  210 (346)
T ss_dssp             HHHHHHHHHHHHHHBCTTSCBCEEEEEECCCTTCHHHHHHHHHHHHHHHTCTTEEEEECCCGG--GCHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHhcCCCCCceEEEEEecCCCCHHHHHHHHHHHHHHHhCCCcEEEEecCCC--CCHHHHHHHHHHHHH
Confidence            667777777754333       78888875  3445667778888877653124433221111  111234445555542


Q NP_000836.2     272 T-PNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 ~-~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      . .++++|+.. .+..+..+++++++.|+.
T Consensus       211 ~~~~~~~i~~~-~~~~a~~~~~al~~~g~~  239 (346)
T 4Y9T_A          211 ANPDIDLIFLH-AAHLSVAAVASLEAAGKK  239 (346)
T ss_dssp             HCTTCCEEEES-SHHHHHHHHHHHHHTTCC
T ss_pred             HCCCCCEEEEC-ChHHHHHHHHHHHHcCCC
Confidence            1 245555544 344556677888877763


No 225
>4RU1_A Monosaccharide ABC transporter substrate-binding protein; SUGAR TRANSPORTER, ABC-TYPE, ENZYME FUNCTION; HET: INS, CIT; 1.5A {Acidothermus cellulolyticus}
Probab=97.08  E-value=9.1e-07  Score=89.26  Aligned_cols=206  Identities=13%  Similarity=0.059  Sum_probs=120.0  Template_Neff=11.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....++++||++.|.++..           .....+..+++.++++.+        +++.+.  + ..++    +...+
T Consensus        14 ~~~~~~~~~Ig~~~~~~~~~-----------~~~~~~~~~~~~~~~~~g--------~~~~~~--~-~~~~----~~~~~   67 (304)
T 4RU1_A           14 GKANTPHLTIAMITHQQPGD-----------TFWDIIRKGALAAAAKDN--------VTLKYS--N-DPDS----TKEAV   67 (304)
T ss_dssp             ---CCCCEEEEEEECCCTTC-----------THHHHHHHHHHHHHHHTT--------EEEEEE--E-CSSH----HHHHH
T ss_pred             cCCCCCCeEEEEEeCCCCCC-----------hHHHHHHHHHHHHHHHcC--------CEEEEe--C-CCCc----HHHHH
Confidence            34567889999999974321           234567778888887753        333332  3 2222    22233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIG-AAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg-~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   ++++++|+ +..+.........+...++|+|..+...+..   ...++++++.+
T Consensus        68 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~---~~~~~~~~v~~  125 (304)
T 4RU1_A           68 LIQDAVN-------------------AKVDGIAVTIPDPPALIPAIKQAVAAGIPVVAFNAGIDQW---KESGALMYFGQ  125 (304)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCSSHHHHHHHHHHHHHTTCCEEEESSCTTTH---HHHTCSEEEEC
T ss_pred             HHHHHHH-------------------cCCCEEEEcCCChHhhHHHHHHHHHCCCCEEEEeCCCccc---cccCCceEEec
Confidence            3444432                   47888887 4333333344456677899999877644321   11345677778


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLA--SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PN  274 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~--~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~  274 (908)
                      ++...+..+++++.+.+.++++++.  .++.++..+.+++++.+++. +..+...   .  .+..+....++++++. .+
T Consensus       126 d~~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~---~--~~~~~~~~~~~~~l~~~~~  199 (304)
T 4RU1_A          126 DETVAGQAAGARATSEGFKHVLCVLQAQGQVQLESRCNGVQQTFKGQ-YTKLYVN---G--ADQPSVRTTIAAKLKQDPS  199 (304)
T ss_dssp             CHHHHHHHHHHHHHHTTCCEEEEEESSSSCHHHHHHHHHHHHHCCSE-EEEEECC---T--TCHHHHHHHHHHHHHHCTT
T ss_pred             CHHHHHHHHHHHHHHcCCceEEEEEcCCCcHHHHHHHHHHHHHHhcC-cceEEEc---C--CChHHHHHHHHHHHhhCCC
Confidence            8777788888888777888999994  33445667777888877764 2333211   1  1112334445555431 23


Q NP_000836.2     275 ARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       275 ~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      +++|++. ++..+..+++++++.|+
T Consensus       200 ~~~i~~~-~~~~~~~~~~~~~~~g~  223 (304)
T 4RU1_A          200 IDLVITL-GAPIAQLAIQAVKDAGS  223 (304)
T ss_dssp             CCEEEES-SHHHHHHHHHHHHHTTC
T ss_pred             CCEEEEC-ChhHHHHHHHHHHHcCC
Confidence            6777644 34456677888887776


No 226
>4YV7_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: MSE; 2.3A {Mycobacterium smegmatis}
Probab=97.08  E-value=9.4e-07  Score=90.21  Aligned_cols=215  Identities=13%  Similarity=0.046  Sum_probs=114.6  Template_Neff=11.900

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      ....++.++||++.|..+.            ..+.....+++.++++.+          +++.+.|+..++.    ...+
T Consensus        34 ~~~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~l~~~~~~~~~~----~~~~   87 (326)
T 4YV7_A           34 APVVDGALKIGFSQATQQS------------PFYVALTDAAKAEAQAQG----------DELFYADANGDIT----KQNN   87 (326)
T ss_dssp             -----CCCEEEEEESCCSS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCHH----HHHH
T ss_pred             CCccCCCcEEEEEeCCCCC------------HHHHHHHHHHHHHHHHcC----------CEEEEEcCCCCHH----HHHH
Confidence            3456778999999997542            245667788888887753          3444555543322    2233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   ++++++++...+... ......+...++|+|..+...+       .++.+.+.+
T Consensus        88 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~~  141 (326)
T 4YV7_A           88 DVQDLIT-------------------RGINVLVINPVDPKGVTPSLAAAEAAGIKVVTVDRPVE-------SGAASFVGR  141 (326)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCEEEEESSCCS-------SCCSEEEEC
T ss_pred             HHHHHHH-------------------cCCCEEEEcCCCccccHHHHHHHHHCCCeEEEeCCCCC-------CCcceEEec
Confidence            3443332                   478877765443322 2344556678999998765432       134556666


Q NP_000836.2     198 PDSYQAQAMVDIVT----ALGWNYVSTLAS-EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-  271 (908)
Q Consensus       198 ~~~~~~~~~~~~l~----~~~~~~v~ii~~-~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-  271 (908)
                      ++...++.+++++.    +.+.+.+.++.. ++.++..+.+++++.+++.+++.+.......  .+..+....++++++ 
T Consensus       142 d~~~~~~~~~~~~~~~l~~~g~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~  219 (326)
T 4YV7_A          142 DNKAMGELVGKAAVDTLGPDGGKIIEIQGDAGGAVARDRRDGFQAAVSGRPNITIVEGPYCD--YIRSKAVTAMQDLLQA  219 (326)
T ss_dssp             CHHHHHHHHHHHHHHHHGGGCEEEEEEECCTTCHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHHHCCCCcEEEEEEcCCCCHHHHHHHHHHHHHHhcCCCeEEeeccccc--CcHHHHHHHHHHHHHH
Confidence            66655655444432    234444444432 3456667778888877664124433211111  111223344555542 


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSD  309 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~  309 (908)
                      ..++|+|++.. +..+..+++++++.|.. ++.+++.+
T Consensus       220 ~~~~~~i~~~~-~~~a~~~~~~l~~~g~~-~~~i~~~~  255 (326)
T 4YV7_A          220 HPDLKGVYAQN-DDMALGAMQVLAENNRT-DVKVFGVD  255 (326)
T ss_dssp             CTTEEEEEESS-HHHHHHHHHHHHHTTCT-TSEEECSB
T ss_pred             CCCCcEEEeCC-hHHHHHHHHHHHHCCCC-CcEEEEec
Confidence            13677776654 44456677888877762 34444443


No 227
>2FN9_B ribose ABC transporter, periplasmic ribose-binding; RBP, ribose binding protein, periplasmic; 1.4A {Thermotoga maritima}
Probab=97.06  E-value=1e-06  Score=88.25  Aligned_cols=202  Identities=10%  Similarity=0.046  Sum_probs=110.6  Template_Neff=11.700

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.|          +++.+.++..+.    +...+.+++++
T Consensus         2 ~~~Ig~v~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~~~~   55 (290)
T 2FN9_B            2 KGKMAIVISTLNN------------PWFVVLAETAKQRAEQLG----------YEATIFDSQNDT----AKESAHFDAII   55 (290)
T ss_dssp             -CEEEEEESCSSS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHHHHHH
T ss_pred             CceEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCH----HHHHHHHHHHH
Confidence            5689999987542            255677788888887653          233444443332    12233334333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++|....+... ......+...++|+|..+...+.     ..++.+++..++...+
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~d~~~~~  111 (290)
T 2FN9_B           56 A-------------------AGYDAIIFNPTDADGSIANVKRAKEAGIPVFCVDRGINA-----RGLAVAQIYSDNYYGG  111 (290)
T ss_dssp             H-------------------HTCSEEEECCSCTTTTHHHHHHHHHTTCCEEEESSCCSC-----SSSSSEEEEECHHHHH
T ss_pred             H-------------------cCCCEEEEcCCCCcccHHHHHHHHHCCCCEEEECCCCCC-----CCCceEEEEeCchHHH
Confidence            2                   477877765433322 13344566789999987764431     1234566677776677


Q NP_000836.2     204 QAMVDIVTALG------WNYVSTLA----SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-T  272 (908)
Q Consensus       204 ~~~~~~l~~~~------~~~v~ii~----~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~  272 (908)
                      +.+++++.+.+      .++++++.    .+..+...+.+++++.+++.+...+.......  .+..+....+++++. .
T Consensus       112 ~~~~~~l~~~~~~~~~~~~~i~~i~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~  189 (290)
T 2FN9_B          112 VLAGEYFVKFLKEKYPDAKEIPYAELLGILSAQPTWDRSNGFHSVVDQYPEFKMVAQQSAE--FDRDTAYKVTEQILQAH  189 (290)
T ss_dssp             HHHHHHHHHHHHHHSTTCSCEEEEEEECCTTCHHHHHHHHHHHHHHTTSTTEEEEEEEECT--TCHHHHHHHHHHHHHHC
T ss_pred             HHHHHHHHHHHHHHCCCccccCEEEEEeeCCCchHHHHHHHHHHHHHhCCCcEEeeeecCC--CCHHHHHHHHHHHHHHC
Confidence            77777765433      26777633    23344556777777777654212222111111  111223344455542 1


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      .++|+|++. ++..+..+++++++.|+
T Consensus       190 ~~~d~i~~~-~~~~a~~~~~~l~~~g~  215 (290)
T 2FN9_B          190 PEIKAIWCG-NDAMALGAMKACEAAGR  215 (290)
T ss_dssp             TTCCEEEES-SHHHHHHHHHHHHHHTC
T ss_pred             CCCCEEEEC-ChHHHHHHHHHHHHcCC
Confidence            367888766 35556778888877776


No 228
>4XXH_B PROTEIN (TREHALOSE OPERON REPRESSOR); LACI FAMILY, PHOSPHATE BINDING, PROTEIN; HET: T6P; 2.4A {Escherichia coli K-12}
Probab=97.06  E-value=1e-06  Score=86.09  Aligned_cols=192  Identities=11%  Similarity=0.087  Sum_probs=114.8  Template_Neff=12.100

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.+        +  ++.+.++..++.    ...+.++++.
T Consensus         2 ~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~~----~~~~~~~~~~   55 (255)
T 4XXH_B            2 DKVVAIIVTRLDS------------LSENLAVQTMLPAFYEQG--------Y--DPIMMESQFSPQ----LVAEHLGVLK   55 (255)
T ss_dssp             CCEEEEEESCTTC------------HHHHHHHHHHHHHHHHHT--------C--EEEEEECTTCHH----HHHHHHHHHH
T ss_pred             CeEEEEEECCCCC------------hhHHHHHHHHHHHHHHcC--------C--EEEEEeCCCCHH----HHHHHHHHHH
Confidence            5789999987542            255667778887777642        2  334444433321    2223333333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQ  204 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~  204 (908)
                      .                   .++|++|+...+...   ...+...++|+|..+...         +.++++.+++...++
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~---~~~~~~~~ip~v~~~~~~---------~~~~~v~~~~~~~~~  104 (255)
T 4XXH_B           56 R-------------------RNIDGVVLFGFTGIT---EEMLAHWQSSLVLLARDA---------KGFASVCYDDEGAIK  104 (255)
T ss_dssp             H-------------------TTCSEEEEECCTTCC---TGGGGGGTTSEEEESSCC---------TTSEEEEECHHHHHH
T ss_pred             h-------------------CCCCEEEEecCCCCc---HHHHHhcCCeEEEECCCC---------CCCCEEEeCHHHHHH
Confidence            2                   478888875544332   234566799988765422         245667777777788


Q NP_000836.2     205 AMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMF  281 (908)
Q Consensus       205 ~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~  281 (908)
                      .+++++.+.+.++++++..+..   ++..+.+++++.+++. ++.+... ...  .+..+....+++++. .++|+|++.
T Consensus       105 ~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~-~~~--~~~~~~~~~~~~~~~-~~~dai~~~  179 (255)
T 4XXH_B          105 ILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAH-KLHPVAA-LPG--LAMKQGYENVAKVIT-PETTALLCA  179 (255)
T ss_dssp             HHHHHHHHTTCCCEEEECCCTTSCCCCCCHHHHHHHHHHHT-TCCCCEE-CCC--SCHHHHHHHGGGGCC-TTCCEEEES
T ss_pred             HHHHHHHHCCCCcEEEEeCChhccccHHHHHHHHHHHHHHC-CCCCcee-cCC--CcchhHHHHHHHHhC-CCCCEEEEe
Confidence            8888887678889999985433   4667778888887764 3433211 111  111123334555553 578888776


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~  299 (908)
                      . +..+..+++++++.|+
T Consensus       180 ~-~~~a~~~~~~~~~~g~  196 (255)
T 4XXH_B          180 T-DTLALGASKYLQEQRI  196 (255)
T ss_dssp             S-HHHHHHHHHHHHHTTC
T ss_pred             c-HHHHHHHHHHHHHCCC
Confidence            4 4456677888877776


No 229
>5IX8_B Putative sugar ABC transport system; Structural Genomics, Midwest Center for; HET: EDO, SO4, MSE; 1.6A {Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)}
Probab=97.04  E-value=1.1e-06  Score=89.41  Aligned_cols=208  Identities=14%  Similarity=0.032  Sum_probs=120.9  Template_Neff=11.700

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVR-ILDTCSRDTYALEQSLT  118 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~-~~d~~~~~~~a~~~~~~  118 (908)
                      ....+.++||++.|..+.            .++.....+++.++++.+        +++.+. ..|+..+.    ....+
T Consensus        10 ~~~~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~~~~~~----~~~~~   65 (321)
T 5IX8_B           10 IVARQPLKLGVTVVHLLD------------NFYKGIAYGIVDEARRSN--------VEVVQVAVAGAYGNV----QQQFA   65 (321)
T ss_dssp             CCCCSCCEEEEEESCSSS------------SHHHHHHHHHHHHHHHHT--------CEEEEEEECSSTTCH----HHHHH
T ss_pred             cccCCCcEEEEEECCCCC------------HHHHHHHHHHHHHHHHCC--------CEEEEEEecCCCCCH----HHHHH
Confidence            345678999999987542            255677888888888763        445543 23332332    22233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAAS-SVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s-~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   .+++++|..... .........+.+.++|+|..+...+.      .++.+++.+
T Consensus        66 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~  120 (321)
T 5IX8_B           66 QLQSFKT-------------------LGVDYAVLSPAAYSGYDPVVADLARSGIKTISAGIPVNS------DKIAFGVLQ  120 (321)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCSSSSSCHHHHHHHHHTTCEEEEESSCCSC------TTCCEEEEC
T ss_pred             HHHHHHH-------------------cCCCEEEEcCCCccccHHHHHHHHHCCCEEEEECCCCCC------CcceEEEEc
Confidence            3444332                   467776654332 22234445666789999987654321      245667777


Q NP_000836.2     198 PDSYQAQAMVDIVTALGW--NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-  272 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~--~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-  272 (908)
                      ++...+..+++++.+.+.  ++++++..  ++.++..+.+++++.+++. ++.+.... .....+..+....++++++. 
T Consensus       121 d~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-g~~~~~~~-~~~~~~~~~~~~~~~~~~~~~  198 (321)
T 5IX8_B          121 DDTLIGKVLGKALCDDGAQGKQVIVVPGAAGLEWPRLRYEGFKEVASAC-GAKLTPAA-FRGEMSLADGMAQTQDLLMRT  198 (321)
T ss_dssp             CHHHHHHHHHHHHHHTTCTTCEEEECCCCSSSSHHHHHHHHHHHHHHHT-TCEECCCC-CCSCCCHHHHHHHHHHHHHHC
T ss_pred             CHHHHHHHHHHHHHHccCCCcEEEEEeCCCCCcHHHHHHHHHHHHHHhc-CCEEEeee-ecCCCCHHHHHHHHHHHHHhC
Confidence            777778888888765554  48888875  4456677888888888765 34443211 11001122344445555421 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      .++++|+... +..+..+++++++.|+
T Consensus       199 ~~~~~i~~~~-~~~a~~~~~~~~~~g~  224 (321)
T 5IX8_B          199 PDAEYVFTPV-TFLGIGAVRAARQANR  224 (321)
T ss_dssp             TTEEEEECSS-HHHHHHHHHHHHHTTC
T ss_pred             CCCCEEEeCC-hHHHHHHHHHHHHcCC
Confidence            2355565543 4455667888887776


No 230
>4WUT_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: FCB, MSE; 1.5A {Agrobacterium vitis}
Probab=97.04  E-value=1.1e-06  Score=89.04  Aligned_cols=222  Identities=9%  Similarity=0.031  Sum_probs=119.1  Template_Neff=11.600

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      ....++..+||++.|..+.            .+...+..+++.++++.+.       ..+.+...|...++    +...+
T Consensus        17 ~l~~~~~~~I~vi~~~~~~------------~~~~~~~~~~~~~~~~~g~-------~~~~~~~~~~~~~~----~~~~~   73 (313)
T 4WUT_A           17 NLYFQSMGEIAVIVKTVNS------------TFWQNVQKGADAAIGKQKA-------HTITFQGPAAESAI----ADQVN   73 (313)
T ss_dssp             -------CEEEEECSCSSC------------HHHHHHHHHHHHHHTTCSS-------CEEEEECCSSTTCH----HHHHH
T ss_pred             cccccCCcEEEEEECCCCC------------HHHHHHHHHHHHHHHhcCc-------eEEEEeCCcccccH----HHHHH
Confidence            3456678999999987542            2456777888888877542       11223222222221    12233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   +++|++|........ ......+...++|+|..+...+..   ....+++.+.+
T Consensus        74 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~---~~~~~~~~v~~  131 (313)
T 4WUT_A           74 MVENAVN-------------------RKVDAILLAPSDPDALVPAVKKAWEARIPVVIIDSMLSKD---AEKYYQAFLAT  131 (313)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCCGG---GGGGCSEEEEC
T ss_pred             HHHHHHh-------------------CCCCEEEECCCCHHhhHHHHHHHHHCCCCEEEEeCCCCcc---hhhheEEEEEC
Confidence            3443332                   478877764433222 233445667899999887644321   01134567777


Q NP_000836.2     198 PDSYQAQAMVDIVTALGW--NYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-T  272 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~--~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~  272 (908)
                      ++...++.+++++.+.+.  ++++++..  +...+..+.+++++.+++.+...+.......  .+..+....+++++. .
T Consensus       132 d~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~  209 (313)
T 4WUT_A          132 DNKAAGELAAKAMIQKVGTEGKIAVMSYVAGAGSEIGRVGGFTDYIKANSKLQIVGPYYSQ--SQMATALNQTTDVLAAN  209 (313)
T ss_dssp             CHHHHHHHHHHHHHHHHCSSSEEEEEESSTTCHHHHHHHHHHHHHHHHHCCCEEEEEEECT--TCHHHHHHHHHHHHHHC
T ss_pred             CHHHHHHHHHHHHHHHHCCCeEEEEEEccCCChhHHHHHHHHHHHHHHcCCcEEEeccCCc--ccHHHHHHHHHHHHHHC
Confidence            777778888888866555  78998875  3345556778888887765312332211111  111223333444432 1


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      .++++|++.. +..+..+++++++.|...++.+++.
T Consensus       210 ~~~~~i~~~~-~~~a~~~~~al~~~g~~~~i~i~~~  244 (313)
T 4WUT_A          210 ADLKGIFGAN-EPTAIGMGRAIKQAGKAGKLVAIGF  244 (313)
T ss_dssp             TTCCEEEECS-HHHHHHHHHHHHHTTCTTSSEEEEE
T ss_pred             CCCCEEEEcC-hhHHHHHHHHHHHcCCCCCEEEEEe
Confidence            3567777664 4455677888887776323444443


No 231
>3HCW_A Maltose operon transcriptional repressor; RNA-BINDING, TRANSCRIPTIONAL REPRESSOR, PSI-2, NYSGXRC; HET: GOL; 2.2A {Staphylococcus aureus subsp. aureus Mu50}
Probab=97.03  E-value=1.2e-06  Score=87.99  Aligned_cols=207  Identities=11%  Similarity=0.084  Sum_probs=118.8  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++..+||++.|.++....       ...+......+++.++++.        |+  ++.+.+...+.    +...+.++
T Consensus         4 ~~~~~~I~~v~~~~~~~~~-------~~~~~~~~~~g~~~~~~~~--------g~--~~~~~~~~~~~----~~~~~~~~   62 (295)
T 3HCW_A            4 TNQTYKIGLVLKGSEEPIR-------LNPFYINVLLGISETCNQH--------GY--GTQTTVSNNMN----DLMDEVYK   62 (295)
T ss_dssp             CCCSCEEEEECSCCCHHHH-------SCHHHHHHHHHHHHHHHTT--------TC--EEEECCCCSHH----HHHHHHHH
T ss_pred             cCCccEEEEEecCCCCccc-------cChHHHHHHHHHHHHHHHh--------CC--EEEEEecCCCc----hhHHHHHH
Confidence            4578899999987431000       0124556677777776653        23  33344433321    12223333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      .++.                   .++|++|+...+.. ..+...+...++|+|..+...+.     ..+.++.+.+++..
T Consensus        63 ~~~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~d~~~  117 (295)
T 3HCW_A           63 MIKQ-------------------RMVDAFILLYSKEN-DPIKQMLIDESMPFIVIGKPTSD-----IDHQFTHIDNDNIL  117 (295)
T ss_dssp             HHHT-------------------TCCSEEEESCCCTT-CHHHHHHHHTTCCEEEESCCCSS-----GGGGSCEEEECHHH
T ss_pred             HHHH-------------------cCCCEEEEeCCCCC-CHHHHHHHHCCCCEEEECCCCCc-----ccccCCEEecChHH
Confidence            3332                   47888887544433 34455667789999988754321     12345667777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL----ETPNA  275 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~----~~~~~  275 (908)
                      .++.+++++.+.+.++++++..+.  ..+..+.++|++.+++. ++.+... ...  .+..+....+++++    ...++
T Consensus       118 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~l~~~-~~~~~~~-~~~--~~~~~~~~~~~~~~~~~~~~~~~  193 (295)
T 3HCW_A          118 ASENLTRHVIEQGVDELIFITEKGNFEVSKDRIQGFETVASQF-NLDYQII-ETS--NEREVILNYMQNLHTRLKDPNIK  193 (295)
T ss_dssp             HHHHHHHHHHHHCCSEEEEEEESSCCHHHHHHHHHHHHHHHHT-TCEEEEE-EEC--SCHHHHHHHHHHHHHHHTCTTSC
T ss_pred             HHHHHHHHHHHcCCCEEEEEeCCCCChhHHHHHHHHHHHHHHC-CCCceEE-ecC--CCHHHHHHHHHHHHHHhcCCCCC
Confidence            888888888767888999988543  25566778888888765 3443211 111  11122333344432    12346


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      |+|++.. +..+..+++++++.|+
T Consensus       194 d~i~~~~-~~~~~~~~~~l~~~g~  216 (295)
T 3HCW_A          194 QAIISLD-AMLHLAILSVLYELNI  216 (295)
T ss_dssp             EEEEESS-HHHHHHHHHHHHHTTC
T ss_pred             cEEEECC-HHHHHHHHHHHHHCCC
Confidence            7777664 4456678888888776


No 232
>1JYE_A Lactose Operon Repressor; Gene Regulation, Protein Stability, Protein; 1.7A {Escherichia coli} SCOP: c.93.1.1
Probab=97.02  E-value=1.2e-06  Score=90.41  Aligned_cols=203  Identities=13%  Similarity=0.080  Sum_probs=115.3  Template_Neff=11.300

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++..+..+++.++++.+        +++.+...+. .++    +...+.++
T Consensus        58 ~~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~~~~~~~~  112 (349)
T 1JYE_A           58 GKQSLLIGVATSSLAL------------HAPSQIVAAILSRADQLG--------ASVVVSMVER-SGV----EACKTAVH  112 (349)
T ss_dssp             ----CEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------CEEEEEECCS-SSH----HHHHHHHH
T ss_pred             cCCCcEEEEEeCCccC------------ccHHHHHHHHHHHHHHcC--------CEEEEEecCC-ChH----HHHHHHHH
Confidence            4578899999987542            255677788888887653        3333322221 121    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+.........+...++|+|..+...+        +.+..+..+...
T Consensus       113 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~--------~~~~~v~~d~~~  165 (349)
T 1JYE_A          113 NLLA-------------------QRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQ--------TPINSIIFSHED  165 (349)
T ss_dssp             HHHT-------------------TTCSCEEEESCCCHHHHHHHHHHTTTSCEEESSSCTT--------SSSCEEEECHHH
T ss_pred             HHHh-------------------cCCCEEEEeCCCCcHHHHHHHHHhcCCCEEEEeCCCC--------CCCCEEEEccHH
Confidence            4332                   4788888764443322222345678999998765322        234455666666


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .+..+++++.+.++++++++..  +..+...+.++|++.+++. ++.+.......  .+..+....+++++. ..++++|
T Consensus       166 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~l~~~-~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~~i  242 (349)
T 1JYE_A          166 GTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRN-QIQPIAEREGD--WSAMSGFQQTMQMLNEGIVPTAM  242 (349)
T ss_dssp             HHHHHHHHHHHHTCCSEEEEECCTTSHHHHHHHHHHHHHHHHT-TCCCSEEEECC--SSHHHHHHHHHHHHHTTCCCSEE
T ss_pred             HHHHHHHHHHHCCCCcEEEEeCCcccHHHHHHHHHHHHHHHHC-CCCCceeeecC--CChhHHHHHHHHHHhcCCCCCEE
Confidence            6777788876668899999985  3345667788888888775 35443211111  111223334455542 1347777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       243 ~~~~-d~~a~~~~~~l~~~g~~  263 (349)
T 1JYE_A          243 LVAN-DQMALGAMRAITESGLR  263 (349)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEcC-HHHHHHHHHHHHHcCCC
Confidence            6654 44566778888887764


No 233
>2PE5_B Lactose operon repressor/DNA Complex; Lac repressor, allosteric effectors, gene; HET: 145; 3.5A {Escherichia coli} SCOP: a.35.1.5, c.93.1.1
Probab=97.02  E-value=1.3e-06  Score=89.42  Aligned_cols=203  Identities=12%  Similarity=0.060  Sum_probs=116.8  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+.++||++.|..+.            .++..+..+++.++++.+        +++.+...+. .++    +...+.++
T Consensus        57 ~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~~~~~~~~  111 (330)
T 2PE5_B           57 GKQLLLIGVATSSLAL------------HAPSQIVAAIKSRADQLG--------ASVVVSMVER-SGV----EACKAAVH  111 (330)
T ss_dssp             TCCCEEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------EEEEEEECCS-CSH----HHHHHHHH
T ss_pred             hCCCCEEEEEeCCCCC------------ccHHHHHHHHHHHHHHcC--------CEEEEEecCC-CcH----HHHHHHHH
Confidence            3568899999987542            245677888888887753        3444433332 221    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+.........+...++|+|..+...+        +.++.+..+...
T Consensus       112 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~--------~~~~~v~~d~~~  164 (330)
T 2PE5_B          112 NLLA-------------------QRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQ--------TPINSIIFSHED  164 (330)
T ss_dssp             HHHH-------------------TTCSEEEEESCCCHHHHHHHHHHSCSSCEEESSSCSS--------SSSCEEEECHHH
T ss_pred             HHHh-------------------CCCCEEEEeCCCCcHHHHHHHHHhcCCCEEEEcCCCC--------CCCCEEEEccHH
Confidence            3332                   4788888754433322222234578999998765422        234455566666


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .+..+++++.+.++++++++..  ++.....+.++|++.+++. ++.+.......  .+..+....+.+++. ..++++|
T Consensus       165 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~~i  241 (330)
T 2PE5_B          165 GTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRN-QIQPIAEREGD--WSAMSGFQQTMQMLNEGIVPTAM  241 (330)
T ss_dssp             HHHHHHHHHHHHTCCSEEEEECCTTSHHHHHHHHHHHHHHHTT-TCCCSCEEECC--SCHHHHHHHHHHHHHHTCCCSEE
T ss_pred             HHHHHHHHHHHCCCCcEEEEeCCcccccHHHHHHHHHHHHHHC-CCCCceeeeCC--CchhHHHHHHHHHHhcCCCCCEE
Confidence            6777778776668889999985  3345566778888888775 34433211111  111122333444442 1247777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|..
T Consensus       242 ~~~~-~~~a~~~~~~l~~~g~~  262 (330)
T 2PE5_B          242 LVAN-DQMALGAMRAITESGLR  262 (330)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEcC-HHHHHHHHHHHHHCCCC
Confidence            6664 44566778888877764


No 234
>3C3K_B Alanine racemase (E.C.5.1.1.1); STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE; HET: GOL; 1.99A {Actinobacillus succinogenes}
Probab=97.01  E-value=1.3e-06  Score=87.08  Aligned_cols=203  Identities=14%  Similarity=0.060  Sum_probs=115.2  Template_Neff=11.800

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..+++.+||++.|....            .++.....+++.++++.+        +  ++.+.+...+.    ....+.+
T Consensus         4 ~~~~~~~I~~~~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~   57 (285)
T 3C3K_B            4 RTAKTGMLLVMVSNIAN------------PFCAAVVKGIEKTAEKNG--------Y--RILLCNTESDL----ARSRSCL   57 (285)
T ss_dssp             ---CCEEEEEEESCTTS------------HHHHHHHHHHHHHHHTTT--------E--EEEEEECTTCH----HHHHHHT
T ss_pred             ccCCCceEEEEecCCCc------------HHHHHHHHHHHHHHHHcC--------C--EEEEEeCCCCH----HHHHHHH
Confidence            34567899999984321            355677888888887753        2  33444443332    1222333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +.+..                   .++|++|+...+.....+ ..+.. ++|+|..+...+       .+..+.+.+++.
T Consensus        58 ~~~~~-------------------~~~d~ii~~~~~~~~~~~-~~~~~-~ip~v~~~~~~~-------~~~~~~v~~d~~  109 (285)
T 3C3K_B           58 TLLSG-------------------KMVDGVITMDALSELPEL-QNIIG-AFPWVQCAEYDP-------LSTVSSVSIDDV  109 (285)
T ss_dssp             HHHHT-------------------TSCSCEEECSCGGGHHHH-HHHHT-TSCEEEESCCCT-------TCSSEEEECCHH
T ss_pred             HHHhc-------------------CCCCEEEEecCCCCcHHH-HHHHh-cCCEEEeCCCCC-------CCCCcEEEeCcH
Confidence            33322                   478888876544332222 22333 899888765432       134566777777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASE--GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~--~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      ..++.+++++.+.+.++++++..+  ......+.++|++.+++. ++.+....... ..+..+....+++++. ..++++
T Consensus       110 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~-~~~~~~~~~~~~~~l~~~~~~~~  187 (285)
T 3C3K_B          110 AASEYVVDQLVKSGKKRIALINHDLAYQYAQHRESGYLNRLKFH-GLDYSRISYAE-NLDYMAGKLATFSLLKSAVKPDA  187 (285)
T ss_dssp             HHHHHHHHHHHHTTCCCEEEEECCTTSHHHHHHHHHHHHHHHHT-TCCCCEEEECS-SSSHHHHHHHHHHHHSSSSCCSE
T ss_pred             HHHHHHHHHHHHCCCCcEEEEecCccchhHHHHHHHHHHHHHHC-CCCCCceeecC-CCchHHHHHHHHHHHhcCCCCCE
Confidence            777788888766678899999853  334566778888887765 34433211110 0111223333444432 134777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       188 i~~~~-~~~a~~~~~al~~~g~~  209 (285)
T 3C3K_B          188 IFAIS-DVLAAGAIQALTESGLS  209 (285)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-hHHHHHHHHHHHHCCCC
Confidence            76664 44567788888887764


No 235
>8ABP_A L-ARABINOSE-BINDING PROTEIN (MUTANT WITH MET; BINDING PROTEINS; HET: GAL, GLA; 1.49A {Escherichia coli} SCOP: c.93.1.1
Probab=97.01  E-value=1.3e-06  Score=88.08  Aligned_cols=214  Identities=12%  Similarity=0.073  Sum_probs=115.1  Template_Neff=11.900

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.+          +++.+.++ .++    +...+.+++++
T Consensus         2 ~~~Ig~~~~~~~~------------~~~~~~~~~~~~~~~~~~----------~~~~~~~~-~~~----~~~~~~~~~l~   54 (306)
T 8ABP_A            2 NLKLGFLVKQPEE------------PWFQTEWKFADKAGKDLG----------FEVIKIAV-PDG----EKTLNAIDSLA   54 (306)
T ss_dssp             CEEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT----------EEEEEEEC-CSH----HHHHHHHHHHH
T ss_pred             CeEEEEEECCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEeC-CCH----HHHHHHHHHHH
Confidence            5789999987542            245667788888877652          33344444 232    22233344433


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIG-AAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg-~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   ++++++|. +..+.........+...++|+|..+...+.... ...++++++.+++...+
T Consensus        55 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~-~~~~~~~~v~~d~~~~~  114 (306)
T 8ABP_A           55 A-------------------SGAKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQFVNAKG-KPMDTVPLVMLAATKIG  114 (306)
T ss_dssp             H-------------------TTCCEEEEECSCGGGHHHHHHHHHHTTCEEEEESSCCBCTTS-CBCTTSCEEEECHHHHH
T ss_pred             H-------------------cCCCEEEEeCCCcchhHHHHHHHHhCCCEEEEEccccccCCC-CCcccccEEeechhHHH
Confidence            2                   46786554 333332234445667789999988765432211 11345677777777777


Q NP_000836.2     204 QAMVDIVTA----LGWN--YVSTLASE---GNYGESGVEAFTQISREIG--GVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       204 ~~~~~~l~~----~~~~--~v~ii~~~---~~~~~~~~~~~~~~~~~~~--~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      +.+++++.+    .+++  +++++..+   ..++..+.++|++.+++.+  ..++.......  .+..+....++++++ 
T Consensus       115 ~~~~~~l~~~~~~~g~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~-  191 (306)
T 8ABP_A          115 ERQGQELYKEMQKRGWDVKESAVMAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKS--NDIPGAFDAANSMLV-  191 (306)
T ss_dssp             HHHHHHHHHHHHHHTCCGGGEEEEEEECTTSHHHHHHHHHHHHHHHHHTCCGGGEEEEECSS--SSHHHHHHHHHHHHT-
T ss_pred             HHHHHHHHHHHHHcCCCcccceEEEEecCCChHHHHHHHHHHHHHHHcCCCcceeeeecCCC--CChhHHHHHHHHHHH-
Confidence            777776643    3555  66666532   2455567778887777642  02222111111  111233444555543 


Q NP_000836.2     273 PNARA---VIMFANEDDIRRILEAAKKLNQS-GHFLWIGS  308 (908)
Q Consensus       273 ~~~~v---iv~~~~~~~~~~~l~~~~~~g~~-~~~~~i~~  308 (908)
                      .+++.   ++++.++..+..+++++++.|+. .++.+++.
T Consensus       192 ~~~~~~~~~i~~~~~~~a~~~~~~~~~~g~~~~~i~i~~~  231 (306)
T 8ABP_A          192 QHPEVKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGI  231 (306)
T ss_dssp             TCTTCSEEEEECSSHHHHHHHHHHHHHTTCCGGGEEEEEE
T ss_pred             HCCCCceEEEEEcchhhHHHHHHHHHhCCCCHhcEEEEEe
Confidence            23443   33444455567788888888764 13444443


No 236
>5ABP_A L-ARABINOSE-BINDING PROTEIN COMPLEX WITH D-GALACTOSE; BINDING PROTEIN; HET: GAL, GLA; 1.8A {Escherichia coli} SCOP: c.93.1.1
Probab=97.01  E-value=1.3e-06  Score=88.06  Aligned_cols=214  Identities=12%  Similarity=0.076  Sum_probs=114.6  Template_Neff=11.900

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++.....+++.++++.+          +++.+.+. .++    ....+.+++++
T Consensus         2 ~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~-~~~----~~~~~~~~~l~   54 (306)
T 5ABP_A            2 NLKLGFLVKQPEE------------PWFQTEWKFADKAGKDLG----------FEVIKIAV-PDG----EKTLNAIDSLA   54 (306)
T ss_dssp             CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT----------CEEEEEEC-CSH----HHHHHHHHHHH
T ss_pred             CcEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEeC-CCH----HHHHHHHHHHH
Confidence            5789999987542            255677788888877652          23333443 232    22233444443


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVI-GAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   ++++++| ++..+.........+...++|+|.++...+.... ...++++++.+++...+
T Consensus        55 ~-------------------~~~d~iii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~-~~~~~~~~v~~d~~~~~  114 (306)
T 5ABP_A           55 A-------------------SGAKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQFVNAKG-KPMDTVPLVMMAATKIG  114 (306)
T ss_dssp             H-------------------TTCCEEEEECSCGGGHHHHHHHHHHTTCEEEEESSCCBCTTS-CBCTTSCEEEECHHHHH
T ss_pred             H-------------------CCCCEEEEeCCCcchHHHHHHHHHhCCCEEEEEcCccccCCC-CCCccceEeeechhHHH
Confidence            2                   4677544 4444333334455667789999988765432111 01235677777776667


Q NP_000836.2     204 QAMVDIVTA----LGWN--YVSTLASE---GNYGESGVEAFTQISREIG--GVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       204 ~~~~~~l~~----~~~~--~v~ii~~~---~~~~~~~~~~~~~~~~~~~--~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      +.+++++.+    .+++  ++.++..+   ..++..+.+++++.+++.+  ..++.......  .+..+....++++++ 
T Consensus       115 ~~~~~~l~~~~~~~g~~~~~i~v~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~--~~~~~~~~~~~~~l~-  191 (306)
T 5ABP_A          115 ERQGQELYKEMQKRGWDVKESAVMAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKS--NDIPGAFDAANSMLV-  191 (306)
T ss_dssp             HHHHHHHHHHHHHTTCCGGGEEEEEEECTTSHHHHHHHHHHHHHHHHTTCCGGGEEEEECSS--SSHHHHHHHHHHHHT-
T ss_pred             HHHHHHHHHHHHHcCCCccccEEEEEEcCCChHHHHHHHHHHHHHHHcCCCCceeEecCCCC--CChHHHHHHHHHHHH-
Confidence            777766533    3555  76666532   2455667778888777642  02222111111  112234455566553 


Q NP_000836.2     273 PNARA---VIMFANEDDIRRILEAAKKLNQS-GHFLWIGS  308 (908)
Q Consensus       273 ~~~~v---iv~~~~~~~~~~~l~~~~~~g~~-~~~~~i~~  308 (908)
                      .+++.   ++++.++..+..+++++++.|+. .++.+++.
T Consensus       192 ~~~~~~~~~i~~~~~~~a~~~~~~~~~~g~~~~~i~v~~~  231 (306)
T 5ABP_A          192 QHPEVKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGI  231 (306)
T ss_dssp             TCTTCCEEEEECSSHHHHHHHHHHHHHTTCCGGGEEEEEE
T ss_pred             HCCCCceEEEEEechHHHHHHHHHHHhCCCChhcEEEEEe
Confidence            23443   23333444567788888887764 13344443


No 237
>4KVF_A Rhamnose ABC transporter, periplasmic rhamnose-binding; structural genomics, PSI-Biology, Protein Structure; HET: GOL; 1.722A {Kribbella flavida}
Probab=96.99  E-value=1.5e-06  Score=89.53  Aligned_cols=217  Identities=11%  Similarity=0.057  Sum_probs=118.1  Template_Neff=11.400

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....+.++||++.|..+.            .++.....+++.++++.|        +++.+...+. .++    ....+
T Consensus        33 ~~~~~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~a~~~~~--------~~v~~~~~~~-~~~----~~~~~   87 (342)
T 4KVF_A           33 NAPLKEGLKIAYLPKQLNN------------PYTDVEVGGGKVAVGEIK--------GEYKLVGPND-ASA----SSQVS   87 (342)
T ss_dssp             TSCCCSSCEEEEECSSSSS------------HHHHHHHHHHHHHHHHTT--------CEEEECCCCT-TCC----CCHHH
T ss_pred             CCCccCCeEEEEEcCCCCC------------hHHHHHHHHHHHHHHHhC--------CEEEEECCCC-CCH----HHHHH
Confidence            3455678999999986542            245667788888888764        2344443332 221    12233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIG-AAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg-~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                      .+++++.                   ++++++|+ +..+.........+...++|+|..+...+.     ..++.+....
T Consensus        88 ~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~v~~~  143 (342)
T 4KVF_A           88 YINTLIQ-------------------QQQDVIVVAANDPNAVCPSLNQARKADIKVVTFDSDAAK-----TCRDAFINQA  143 (342)
T ss_dssp             HHHHHHH-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCEEEEESSCCCG-----GGCSEEEESS
T ss_pred             HHHHHHH-------------------cCCCEEEEcCCCHHhhHHHHHHHHHCCCEEEEECCCCcc-----cccceEeeCC
Confidence            3444332                   47888887 333333334445566789999987654331     1122233222


Q NP_000836.2     198 PDSYQAQAMVDIVTALG--WNYVSTLAS--EGNYGESGVEAFTQISREI--GGVCIAQSQKIPREPRPGEFEKIIKRLLE  271 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~--~~~v~ii~~--~~~~~~~~~~~~~~~~~~~--~~i~v~~~~~~~~~~~~~~~~~~~~~l~~  271 (908)
                      +....++.+++++.+.+  .++++++..  ++.+...+.++|++.+++.  .++++.......  .+..+....++++++
T Consensus       144 ~~~~~~~~~~~~l~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~  221 (342)
T 4KVF_A          144 TTQGIGESLVKMAKELAGGSGEIAVLSATPNATNQNSWIEVMKTELAKPENAKLKLVKIAYGN--DDDQKSFTEAQGLLQ  221 (342)
T ss_dssp             CHHHHHHHHHHHHHHHTTTCEEEEEEESCTTCHHHHHHHHHHHHHHTSGGGTTEEEEEEEECT--TCHHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHHhCCCcEEEEEECCCCchhHHHHHHHHHHHHcCcccCCcEEEEEeeCC--CCHHHHHHHHHHHHH
Confidence            22446677777775533  688999874  3345566777887777642  123332211111  112234445555553


Q NP_000836.2     272 T-PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIG  307 (908)
Q Consensus       272 ~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~  307 (908)
                      . .++++|++.. +..+..+++++++.++..++.+++
T Consensus       222 ~~~~~~~i~~~~-~~~~~~~~~~~~~~g~~~~v~i~~  257 (342)
T 4KVF_A          222 SYPNLKVIVSPT-TVGIAAASRYVSASSYKGKVAITG  257 (342)
T ss_dssp             HCTTEEEEEECS-HHHHHHHHHHHHTSTTTTTSEEEE
T ss_pred             HCCCccEEEEcC-hhHHHHHHHHHHHcCCCCceEEEE
Confidence            1 2456666553 345566777777777632333443


No 238
>3EDC_D Lactose operon repressor; Lac-repressor, allosteric, tetramer, DNA-binding, Repressor; HET: HEZ; 2.1A {Escherichia coli K12}
Probab=96.98  E-value=1.5e-06  Score=90.23  Aligned_cols=204  Identities=12%  Similarity=0.068  Sum_probs=115.8  Template_Neff=11.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...+.++||++.|..+.            .++..+.++++.++++.+        +++.+...+. .++    +...+.+
T Consensus        57 ~~~~~~~I~~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~~~~~~~  111 (360)
T 3EDC_D           57 AGKQSLLIGVATSSLAL------------HAPSQIVAAIKSRADQLG--------ASVVVSMVER-SGV----EACKAAV  111 (360)
T ss_dssp             ----CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT--------CEEEEEECCT-TCH----HHHHHHH
T ss_pred             ccCCCCEEEEEeCCccC------------ccHHHHHHHHHHHHHHcC--------CEEEEEecCC-ChH----HHHHHHH
Confidence            34578899999987542            255677788888887753        3444433332 221    1223334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   +++|++|+...+.........+...++|+|..+...+        +.++.+..+..
T Consensus       112 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~--------~~~~~v~~d~~  164 (360)
T 3EDC_D          112 HNLLA-------------------QRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQ--------TPINSIIFSHE  164 (360)
T ss_dssp             HHHHH-------------------TTCSEEEEESCCCHHHHHHHHHHTTTSCEEESSSCTT--------SSSCEEEECHH
T ss_pred             HHHHH-------------------CCCCEEEEeCCCCcHHHHHHHHHhcCCCEEEEcCCCC--------CCCCEEEEccH
Confidence            43332                   4788888764443322222235678999998765432        23455666666


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ..+..+++++.+.+.++++++..  ++.....+.++|++.+++. ++.+.......  .+.......+++++.. .++|+
T Consensus       165 ~~~~~~~~~l~~~g~~~i~~l~~~~~~~~~~~r~~g~~~~l~~~-~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~d~  241 (360)
T 3EDC_D          165 DGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRN-QIQPIAEREGD--WSAMSGFQQTMQMLNEGIVPTA  241 (360)
T ss_dssp             HHHHHHHHHHHHHTCCCEEEEECCTTSHHHHHHHHHHHHHHHHT-TCCCSEEEECC--SSHHHHHHHHHHHHHTTCCCSE
T ss_pred             HHHHHHHHHHHHCCCCcEEEEeCCcccccHHHHHHHHHHHHHHC-CCCCceeeecC--CChhhHHHHHHHHHhcCCCCCE
Confidence            66777777776667889999885  3445667788888888775 34443211111  1111223344444421 24777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       242 i~~~~-~~~a~~~~~~l~~~g~~  263 (360)
T 3EDC_D          242 MLVAN-DQMALGAMRAITESGLR  263 (360)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            76654 44566777888877764


No 239
>3KJX_D Transcriptional regulator, LacI family; Transcriptional regulator, Lacl family, Protein; 2.33A {Silicibacter pomeroyi}
Probab=96.97  E-value=1.6e-06  Score=89.40  Aligned_cols=204  Identities=12%  Similarity=0.070  Sum_probs=117.7  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+..+||++.|..+.            .+...+..+++.++++.+        +  ++.+.+...++    +...+.++
T Consensus        65 ~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~l~  118 (344)
T 3KJX_D           65 SNRVNLVAVIIPSLSN------------MVFPEVLTGINQVLEDTE--------L--QPVVGVTDYLP----EKEEKVLY  118 (344)
T ss_dssp             SSCCSEEEEEESCSSS------------SSHHHHHHHHHHHHTTSS--------C--EEEEEECTTCH----HHHHHHHH
T ss_pred             hCCCCeEEEEecCccc------------chHHHHHHHHHHHHHHcC--------C--EEEEEeCCCCH----HHHHHHHH
Confidence            3567899999986532            245567778777776642        2  33344433332    22233444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+....... .....+...++|+|..+....       .+..+.+..++..
T Consensus       119 ~l~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  171 (344)
T 3KJX_D          119 EMLS-------------------WRPSGVIIAGLEHSE-AARAMLDAAGIPVVEIMDSDG-------KPVDAMVGISHRR  171 (344)
T ss_dssp             HHHT-------------------TCCSEEEEECSCCCS-HHHHHHHTCSSCEEEEEECSS-------CCSSCEEEECHHH
T ss_pred             HHHh-------------------cCCCEEEEeCCCCCH-HHHHHHHHcCCCEEEEeCCCC-------CCcCceeEechHH
Confidence            4332                   467888765433322 344556678999998765321       2345566777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEG---NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~---~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      .++.+++++.+.+.++++++....   .....+.++|++.+++. ++.+..........+..+....++++++. .++++
T Consensus       172 ~g~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~  250 (344)
T 3KJX_D          172 AGREMAQAILKAGYRRIGFMGTKMPLDYRARKRFEGFTEVLGKN-GVEIEDREFYSGGSALAKGREMTQAMLERSPDLDF  250 (344)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEESSTTTCHHHHHHHHHHHHHHHHT-TCCCSEEEECCSCCCHHHHHHHHHHHHHHCTTCCE
T ss_pred             HHHHHHHHHHHcCCCcEEEEccCCCCChHHHHHHHHHHHHHHHC-CCCcCcceeecCCCcHHHHHHHHHHHHHhCCCCCE
Confidence            788888888766888999988543   35566778888888775 34443211111011112233445555421 24666


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|..
T Consensus       251 i~~~~-~~~a~~~~~~l~~~g~~  272 (344)
T 3KJX_D          251 LYYSN-DMIAAGGLLYLLEQGID  272 (344)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            66553 44566777788777763


No 240
>3KJX_C Transcriptional regulator, LacI family; Transcriptional regulator, Lacl family, Protein; HET: MSE; 2.33A {Silicibacter pomeroyi}
Probab=96.97  E-value=1.6e-06  Score=89.40  Aligned_cols=204  Identities=12%  Similarity=0.070  Sum_probs=117.7  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+..+||++.|..+.            .+...+..+++.++++.+        +  ++.+.+...++    +...+.++
T Consensus        65 ~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~l~  118 (344)
T 3KJX_C           65 SNRVNLVAVIIPSLSN------------MVFPEVLTGINQVLEDTE--------L--QPVVGVTDYLP----EKEEKVLY  118 (344)
T ss_dssp             SSCCSEEEEEESCSSS------------SSHHHHHHHHHHHHHTSS--------C--EEEEEECTTCH----HHHHHHHH
T ss_pred             hCCCCeEEEEecCccc------------chHHHHHHHHHHHHHHcC--------C--EEEEEeCCCCH----HHHHHHHH
Confidence            3567899999986532            245567778777776642        2  33344433332    22233444


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+....... .....+...++|+|..+....       .+..+.+..++..
T Consensus       119 ~l~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  171 (344)
T 3KJX_C          119 EMLS-------------------WRPSGVIIAGLEHSE-AARAMLDAAGIPVVEIMDSDG-------KPVDAMVGISHRR  171 (344)
T ss_dssp             HHHT-------------------TCCSEEEEECSCCCH-HHHHHHHHCSSCEEEEEECTT-------CCSSEEEEECHHH
T ss_pred             HHHh-------------------cCCCEEEEeCCCCCH-HHHHHHHHcCCCEEEEeCCCC-------CCcCceeEechHH
Confidence            4332                   467888765433322 344556678999998765321       2345566777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEG---NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~---~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      .++.+++++.+.+.++++++....   .....+.++|++.+++. ++.+..........+..+....++++++. .++++
T Consensus       172 ~g~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~  250 (344)
T 3KJX_C          172 AGREMAQAILKAGYRRIGFMGTKMPLDYRARKRFEGFTEVLGKN-GVEIEDREFYSGGSALAKGREMTQAMLERSPDLDF  250 (344)
T ss_dssp             HHHHHHHHHHTTTCCSEEEECCSTTTCHHHHHHHHHHHHHHHTT-TCCEEEEECCSSCCCHHHHHHHHHHHHHHCTTCCE
T ss_pred             HHHHHHHHHHHcCCCcEEEEccCCCCChHHHHHHHHHHHHHHHC-CCCcCcceeecCCCcHHHHHHHHHHHHHhCCCCCE
Confidence            788888888766888999988543   35566778888888775 34443211111011112233445555421 24666


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|..
T Consensus       251 i~~~~-~~~a~~~~~~l~~~g~~  272 (344)
T 3KJX_C          251 LYYSN-DMIAAGGLLYLLEQGID  272 (344)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            66553 44566777788777763


No 241
>1GLG_A GALACTOSE/GLUCOSE-BINDING PROTEIN COMPLEXED WITH D-GALACTOSE; GALACTOSE-BINDING PROTEIN; HET: GAL; 2.0A {Escherichia coli} SCOP: c.93.1.1
Probab=96.97  E-value=1.6e-06  Score=87.65  Aligned_cols=217  Identities=13%  Similarity=0.037  Sum_probs=117.0  Template_Neff=11.900

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++..+..+++.++++.+       |  +++.+.|+..+.    +...+.+++++
T Consensus         2 ~~~Ig~v~~~~~~------------~~~~~~~~~~~~~~~~~~-------g--~~~~~~~~~~~~----~~~~~~~~~l~   56 (309)
T 1GLG_A            2 DTRIGVTIYKYDD------------NFMSVVRKAIEQDAKAAP-------D--VQLLMNDSQNDQ----SKQNDQIDVLL   56 (309)
T ss_dssp             CEEEEEEESCTTC------------HHHHHHHHHHHHHHHTCT-------T--EEEEEEECTTCH----HHHHHHHHHHH
T ss_pred             CcEEEEEEccCCC------------HHHHHHHHHHHHHHHhCC-------C--CeEEEecCCCCH----HHHHHHHHHHH
Confidence            5789999987542            255677788888887653       2  234444443332    22233344333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   ++++++|+...+... ......+...++|+|..+...+.... ...++.+++.+++...+
T Consensus        57 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~-~~~~~~~~v~~d~~~~~  116 (309)
T 1GLG_A           57 A-------------------KGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKAL-DSYDKAYYVGTDSKESG  116 (309)
T ss_dssp             H-------------------TTCSEEEECCSSGGGHHHHHHHHHTTTCCEEEESSCCCHHHH-HTCTTEEEEECCHHHHH
T ss_pred             H-------------------CCCCEEEEeCCChhHHHHHHHHHhhCCCCEEEEccCCChhhc-ccCCcceEEecCcHHHH
Confidence            2                   477877764433322 23445566789999987764432110 01245667777776666


Q NP_000836.2     204 QAMVDIVT-A----L-------GWNYVSTLA--SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRL  269 (908)
Q Consensus       204 ~~~~~~l~-~----~-------~~~~v~ii~--~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l  269 (908)
                      +.+++++. +    .       +.++++++.  .++.++..+.+++++.+++. ++.+........+....+....++++
T Consensus       117 ~~~~~~~~~~l~~~~g~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~  195 (309)
T 1GLG_A          117 IIQGDLIAKHWAANQGWDLNKDGQIQFVLLKGEPGHPDAEARTTYVIKELNDK-GIKTEQLQLDTAMWDTAQAKDKMDAW  195 (309)
T ss_dssp             HHHHHHHHHHHHHCGGGCTTCSSSEEEEEEECSTTCHHHHHHHHHHHHHHHHT-TCCEEEEEEEECTTCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHccCCccCCCCcEEEEEEEcCCCCccHHHHHHHHHHHHHhc-CCceeEeeccccCCCHHHHHHHHHHH
Confidence            66654432 1    1       457788884  33445566777888877764 34432211111001112333445555


Q NP_000836.2     270 LET---PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSD  309 (908)
Q Consensus       270 ~~~---~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~  309 (908)
                      ++.   .++++|++.. +..+..+++++++.|.. ++.+++.+
T Consensus       196 ~~~~~~~~~~~i~~~~-~~~a~~~~~~l~~~g~~-~~~v~~~~  236 (309)
T 1GLG_A          196 LSGPNANKIEVVIANN-DAMAMGAVEALKAHNKS-SIPVFGVD  236 (309)
T ss_dssp             TTSTTTTTCCEEEESS-HHHHHHHHHHHHHTTCT-TSCEECSB
T ss_pred             HcCCCCCCCCEEEECC-HHHHHHHHHHHHHCCCC-CCCEEEec
Confidence            421   3567777664 44556678888877762 33444443


No 242
>2FVY_A D-galactose-binding periplasmic protein; PERIPLASMIC BINDING PROTIEN, HINGE, CHEMOTAXIS; HET: BGC; 0.92A {Escherichia coli} SCOP: c.93.1.1
Probab=96.97  E-value=1.6e-06  Score=87.65  Aligned_cols=217  Identities=13%  Similarity=0.037  Sum_probs=117.0  Template_Neff=11.900

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++..+..+++.++++.+       |  +++.+.|+..+.    +...+.+++++
T Consensus         2 ~~~Ig~v~~~~~~------------~~~~~~~~~~~~~~~~~~-------g--~~~~~~~~~~~~----~~~~~~~~~l~   56 (309)
T 2FVY_A            2 DTRIGVTIYKYDD------------NFMSVVRKAIEQDAKAAP-------D--VQLLMNDSQNDQ----SKQNDQIDVLL   56 (309)
T ss_dssp             CEEEEEEESCTTS------------HHHHHHHHHHHHHHHTCT-------T--EEEEEEECTTCH----HHHHHHHHHHH
T ss_pred             CcEEEEEEccCCC------------HHHHHHHHHHHHHHHhCC-------C--CeEEEecCCCCH----HHHHHHHHHHH
Confidence            5789999987542            255677788888887653       2  234444443332    22233344333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   ++++++|+...+... ......+...++|+|..+...+.... ...++.+++.+++...+
T Consensus        57 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~~~~~-~~~~~~~~v~~d~~~~~  116 (309)
T 2FVY_A           57 A-------------------KGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKAL-DSYDKAYYVGTDSKESG  116 (309)
T ss_dssp             H-------------------TTCSEEEECCSSGGGHHHHHHHHHTTTCCEEEESSCCCHHHH-HTCTTEEEEECCHHHHH
T ss_pred             H-------------------CCCCEEEEeCCChhHHHHHHHHHhhCCCCEEEEccCCChhhc-ccCCcceEEecCcHHHH
Confidence            2                   477877764433322 23445566789999987764432110 01245667777776666


Q NP_000836.2     204 QAMVDIVT-A----L-------GWNYVSTLA--SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRL  269 (908)
Q Consensus       204 ~~~~~~l~-~----~-------~~~~v~ii~--~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l  269 (908)
                      +.+++++. +    .       +.++++++.  .++.++..+.+++++.+++. ++.+........+....+....++++
T Consensus       117 ~~~~~~~~~~l~~~~g~~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~  195 (309)
T 2FVY_A          117 IIQGDLIAKHWAANQGWDLNKDGQIQFVLLKGEPGHPDAEARTTYVIKELNDK-GIKTEQLQLDTAMWDTAQAKDKMDAW  195 (309)
T ss_dssp             HHHHHHHHHHHHHCGGGCTTCSSSEEEEEEECSTTCHHHHHHHHHHHHHHHHT-TCCEEEEEEEECTTCHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHccCCccCCCCcEEEEEEEcCCCCccHHHHHHHHHHHHHhc-CCceeEeeccccCCCHHHHHHHHHHH
Confidence            66654432 1    1       457788884  33445566777888877764 34432211111001112333445555


Q NP_000836.2     270 LET---PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGSD  309 (908)
Q Consensus       270 ~~~---~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~~  309 (908)
                      ++.   .++++|++.. +..+..+++++++.|.. ++.+++.+
T Consensus       196 ~~~~~~~~~~~i~~~~-~~~a~~~~~~l~~~g~~-~~~v~~~~  236 (309)
T 2FVY_A          196 LSGPNANKIEVVIANN-DAMAMGAVEALKAHNKS-SIPVFGVD  236 (309)
T ss_dssp             HTSTTGGGCCEEEESS-HHHHHHHHHHHHHTTCT-TSCEECSB
T ss_pred             HcCCCCCCCCEEEECC-HHHHHHHHHHHHHCCCC-CCCEEEec
Confidence            421   3567777664 44556678888877762 33444443


No 243
>3M9W_A D-xylose-binding periplasmic protein; xylose binding protein, xylose, conformational; 2.15A {Escherichia coli}
Probab=96.97  E-value=1.6e-06  Score=87.92  Aligned_cols=211  Identities=9%  Similarity=0.051  Sum_probs=115.4  Template_Neff=11.500

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||+++|....            .++.....+++.++++.+          +++.+.|...++.    ...+.+++++
T Consensus         2 ~~~Igvv~~~~~~------------~~~~~~~~g~~~a~~~~g----------~~l~~~~~~~~~~----~~~~~~~~l~   55 (313)
T 3M9W_A            2 EVKIGMAIDDLRL------------ERWQKDRDIFVKKAESLG----------AKVFVQSANGNEE----TQMSQIENMI   55 (313)
T ss_dssp             -CEEEEEESCCSS------------STTHHHHHHHHHHHHHTS----------CEEEEEECTTCHH----HHHHHHHHHH
T ss_pred             CcEEEEEeCCCcc------------hHHHhhHHHHHHHHHHcC----------CEEEEEeCCCCHH----HHHHHHHHHH
Confidence            5789999985422            245567778888777642          3444555443322    2233344433


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++|....... .......+...++|+|..+...+.      .++.+++..++...+
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~~~~  110 (313)
T 3M9W_A           56 N-------------------RGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMIND------ADIDFYISFDNEKVG  110 (313)
T ss_dssp             H-------------------TTCSEEEEECSSTTSCHHHHHHHHTTTCEEEEESSCCTT------SCCSEEEEECHHHHH
T ss_pred             H-------------------CCCCEEEEecCCcchHHHHHHHHHHCCCEEEEECCCCCC------CCccEEEECCHHHHH
Confidence            2                   46777765433322 224445566789999987654321      234466777777777


Q NP_000836.2     204 QAMVDIVTALG-WNYVSTLAS--EGNYGESGVEAFTQISREIG---GVCIAQSQKIPREPRPGEFEKIIKRLLET--PNA  275 (908)
Q Consensus       204 ~~~~~~l~~~~-~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~---~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--~~~  275 (908)
                      ..+++++.+.+ .++++++..  +..++..+.+++++.+++.+   .+.+....... ..+..+....++++++.  .++
T Consensus       111 ~~~~~~l~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  189 (313)
T 3M9W_A          111 ELQAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVD-GWLPENALKIMENALTANNNKI  189 (313)
T ss_dssp             HHHHHHHHHHCSSEEEEEEESCTTCHHHHHHHHHHHHHHHHHHHTTSEEEEEEEECG-GGCHHHHHHHHHHHHHHTTTCC
T ss_pred             HHHHHHHHHhCCCCCEEEEeCCCCChhHHHHHHHHHHHHHHhHHcCCeEEEccccCC-CCCHHHHHHHHHHHHHHCCCCC
Confidence            77888775544 345777764  23455667777877776642   02222111110 01112334445555421  357


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|++.. +..+..+++++++.|+..++.+++.
T Consensus       190 d~i~~~~-~~~a~~~~~~~~~~g~~~~i~vig~  221 (313)
T 3M9W_A          190 DAVVASN-DATAGGAIQALSAQGLSGKVAISGQ  221 (313)
T ss_dssp             CEEEESS-HHHHHHHHHHHHTTTCTTTSEECCC
T ss_pred             CEEEECC-hHHHHHHHHHHHHCCCCCCcEEecC
Confidence            7877664 4456677888887776323334433


No 244
>3MA0_A D-xylose-binding periplasmic protein; xylose binding protein, xylose, conformational; HET: XYP; 2.2A {Escherichia coli}
Probab=96.97  E-value=1.6e-06  Score=87.92  Aligned_cols=211  Identities=9%  Similarity=0.051  Sum_probs=115.9  Template_Neff=11.500

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||+++|....            .++.....+++.++++.+          +++.+.|...++.    ...+.+++++
T Consensus         2 ~~~Igvv~~~~~~------------~~~~~~~~g~~~a~~~~g----------~~l~~~~~~~~~~----~~~~~~~~l~   55 (313)
T 3MA0_A            2 EVKIGMAIDDLRL------------ERWQKDRDIFVKKAESLG----------AKVFVQSANGNEE----TQMSQIENMI   55 (313)
T ss_dssp             CCEEEEEESCSCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECSSCHH----HHHHHHHHHH
T ss_pred             CcEEEEEeCCCcc------------hHHHhhHHHHHHHHHHcC----------CEEEEEeCCCCHH----HHHHHHHHHH
Confidence            5789999985422            245567778888777642          3444555443322    2233344433


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++|....... .......+...++|+|..+...+.      .++.+++..++...+
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~~~~  110 (313)
T 3MA0_A           56 N-------------------RGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMIND------ADIDFYISFDNEKVG  110 (313)
T ss_dssp             H-------------------TTCSEEEECCSSTTSCHHHHHHHHHTTCEEEEESSCCCS------SCCSEEEEECHHHHH
T ss_pred             H-------------------CCCCEEEEecCCcchHHHHHHHHHHCCCEEEEECCCCCC------CCccEEEECCHHHHH
Confidence            2                   46777765433322 224445566789999987654321      234466777777777


Q NP_000836.2     204 QAMVDIVTALG-WNYVSTLAS--EGNYGESGVEAFTQISREIG---GVCIAQSQKIPREPRPGEFEKIIKRLLET--PNA  275 (908)
Q Consensus       204 ~~~~~~l~~~~-~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~---~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--~~~  275 (908)
                      ..+++++.+.+ .++++++..  +..++..+.+++++.+++.+   .+.+....... ..+..+....++++++.  .++
T Consensus       111 ~~~~~~l~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  189 (313)
T 3MA0_A          111 ELQAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVD-GWLPENALKIMENALTANNNKI  189 (313)
T ss_dssp             HHHHHHHHHHCSSEEEEEEECCTTCHHHHHHHHHHHHHHHHHHHTTSEEEEEEEECG-GGCHHHHHHHHHHHHHHTTTCC
T ss_pred             HHHHHHHHHhCCCCCEEEEeCCCCChhHHHHHHHHHHHHHHhHHcCCeEEEccccCC-CCCHHHHHHHHHHHHHHCCCCC
Confidence            77888775544 345777764  23455667777877776642   02222111110 01112334445555421  357


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|++.. +..+..+++++++.|+..++.+++.
T Consensus       190 d~i~~~~-~~~a~~~~~~~~~~g~~~~i~vig~  221 (313)
T 3MA0_A          190 DAVVASN-DATAGGAIQALSAQGLSGKVAISGQ  221 (313)
T ss_dssp             CEEEESS-HHHHHHHHHHHHTTTCTTTSEECCC
T ss_pred             CEEEECC-hHHHHHHHHHHHHCCCCCCcEEecC
Confidence            7877664 4456677888887776323334433


No 245
>3MA0_C D-xylose-binding periplasmic protein; xylose binding protein, xylose, conformational; HET: XYP; 2.2A {Escherichia coli}
Probab=96.97  E-value=1.6e-06  Score=87.92  Aligned_cols=211  Identities=9%  Similarity=0.051  Sum_probs=115.9  Template_Neff=11.500

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||+++|....            .++.....+++.++++.+          +++.+.|...++.    ...+.+++++
T Consensus         2 ~~~Igvv~~~~~~------------~~~~~~~~g~~~a~~~~g----------~~l~~~~~~~~~~----~~~~~~~~l~   55 (313)
T 3MA0_C            2 EVKIGMAIDDLRL------------ERWQKDRDIFVKKAESLG----------AKVFVQSANGNEE----TQMSQIENMI   55 (313)
T ss_dssp             CCEEEEEECCSCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCHH----HHHHHHHHHH
T ss_pred             CcEEEEEeCCCcc------------hHHHhhHHHHHHHHHHcC----------CEEEEEeCCCCHH----HHHHHHHHHH
Confidence            5789999985422            245567778888777642          3444555443322    2233344433


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++|....... .......+...++|+|..+...+.      .++.+++..++...+
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~~~~  110 (313)
T 3MA0_C           56 N-------------------RGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMIND------ADIDFYISFDNEKVG  110 (313)
T ss_dssp             H-------------------HTCSEEEECCSSTTSCHHHHHHHHHTTCEEEEESSCCTT------SCCSEEEEECHHHHH
T ss_pred             H-------------------CCCCEEEEecCCcchHHHHHHHHHHCCCEEEEECCCCCC------CCccEEEECCHHHHH
Confidence            2                   46777765433322 224445566789999987654321      234466777777777


Q NP_000836.2     204 QAMVDIVTALG-WNYVSTLAS--EGNYGESGVEAFTQISREIG---GVCIAQSQKIPREPRPGEFEKIIKRLLET--PNA  275 (908)
Q Consensus       204 ~~~~~~l~~~~-~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~---~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--~~~  275 (908)
                      ..+++++.+.+ .++++++..  +..++..+.+++++.+++.+   .+.+....... ..+..+....++++++.  .++
T Consensus       111 ~~~~~~l~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~  189 (313)
T 3MA0_C          111 ELQAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVD-GWLPENALKIMENALTANNNKI  189 (313)
T ss_dssp             HHHHHHHHHHCCSEEEEEEECCTTCHHHHHHHHHHHHHHHHHHHTTSEEEEEEEECG-GGCHHHHHHHHHHHHHHTTTCC
T ss_pred             HHHHHHHHHhCCCCCEEEEeCCCCChhHHHHHHHHHHHHHHhHHcCCeEEEccccCC-CCCHHHHHHHHHHHHHHCCCCC
Confidence            77888775544 345777764  23455667777877776642   02222111110 01112334445555421  357


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|++.. +..+..+++++++.|+..++.+++.
T Consensus       190 d~i~~~~-~~~a~~~~~~~~~~g~~~~i~vig~  221 (313)
T 3MA0_C          190 DAVVASN-DATAGGAIQALSAQGLSGKVAISGQ  221 (313)
T ss_dssp             CEEEESS-HHHHHHHHHHHHTTTCTTTSEECCC
T ss_pred             CEEEECC-hHHHHHHHHHHHHCCCCCCcEEecC
Confidence            7877664 4456677888887776323334433


No 246
>5IBQ_A Probable ribose ABC transporter, substrate-binding; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: XXM; 1.2A {Rhizobium etli}
Probab=96.97  E-value=1.6e-06  Score=87.77  Aligned_cols=217  Identities=10%  Similarity=0.036  Sum_probs=115.8  Template_Neff=11.500

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      .....++..+||+++|..+.            .++.....+++.++++.+          +++.+.+...++    +...
T Consensus        17 ~~~~~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~   70 (310)
T 5IBQ_A           17 NLYFQSMADLIAIITPAHDN------------PFFKAEAVGAEAKAKELG----------YETLVMTHDDDA----NKQS   70 (310)
T ss_dssp             ------CCCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHH
T ss_pred             ccceeeCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCH----HHHH
Confidence            34556788999999997542            255667778888777642          334444443332    2223


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +.+++++.                   .+++++|+...... .......+.+.++|+|..+...+.     ..++++++.
T Consensus        71 ~~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~  126 (310)
T 5IBQ_A           71 EMIDTAIG-------------------RGAKAIILDNAGADASVAAVKKAKDAGIPSFLIDREINA-----TGVAVAQIV  126 (310)
T ss_dssp             HHHHHHHH-------------------TTCSEEEECCSCTTTTHHHHHHHHHTTCCEEEESSCCSC-----SSSSSEEEE
T ss_pred             HHHHHHHH-------------------CCCCEEEEeCCCchhhHHHHHHHHHCCCCEEEeCCCCCC-----CCCceEEEE
Confidence            33343332                   46787776443332 223344566789999987754321     123456677


Q NP_000836.2     197 PPDSYQAQAMVDIVTALGWN--YVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-  271 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~~~~~--~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-  271 (908)
                      .+....++.+++++.+.+.+  +++++..  +..++..+.+++++.+++.+...+.......  .+..+....++++++ 
T Consensus       127 ~d~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~  204 (310)
T 5IBQ_A          127 SNNYQGAQLGAQEFVKLMGEKGNYVELVGKESDTNAGIRSQGYHDVIDDYPEMKSVAKQSAN--WSQTEAYSKMETILQA  204 (310)
T ss_dssp             ECHHHHHHHHHHHHHHHTTTCEEEEEEECCTTSHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHH
T ss_pred             cChHHHHHHHHHHHHHHhCCcceEEEEEcCCCChhHHHHHHHHHHHHHHCCCeEEEEEeeCC--CCHHHHHHHHHHHHHH
Confidence            77777777888887654433  3555553  2344566777888877764212221111111  111223344455542 


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ..++++|++.. +..+..+++++++.|.. ++.+++.
T Consensus       205 ~~~~~~i~~~~-~~~a~~~~~al~~~g~~-~i~vv~~  239 (310)
T 5IBQ_A          205 NPDIKGVISGN-DTMAMGAIAALQAAGRK-DVIVVGF  239 (310)
T ss_dssp             CCSCCEEEESS-HHHHHHHHHHHHHTTCT-TSEEECS
T ss_pred             CCCCCEEEECC-hHHHHHHHHHHHHCCCC-CcEEEEe
Confidence            13577776654 44566777788777762 3344443


No 247
>3K9C_B Transcriptional regulator, LacI family protein; PSI-II, 11026W, LacI family protein; HET: GOL; 2.14A {Rhodococcus jostii}
Probab=96.96  E-value=1.7e-06  Score=86.50  Aligned_cols=201  Identities=16%  Similarity=0.153  Sum_probs=116.7  Template_Neff=11.800

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++++||++.|.++             .++.....+++.++++.+          +++.+.++..+ .    ...+.+
T Consensus         8 ~~~~~~~I~~i~~~~~-------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~-~----~~~~~~   59 (289)
T 3K9C_B            8 RQASSRLLGVVFELQQ-------------PFHGDLVEQIYAAATRRG----------YDVMLSAVAPS-R----AEKVAV   59 (289)
T ss_dssp             -CCSSEEEEEEEETTC-------------HHHHHHHHHHHHHHHHTT----------EEEEEEEEBTT-B----CHHHHH
T ss_pred             hhCCCCeEEEEeCCCC-------------hhHHHHHHHHHHHHHHCC----------CeEEEEeCCCC-H----HHHHHH
Confidence            3457899999987543             245667788888877653          23334443322 1    122333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++..                   .++|++|+...+.....+ ..+ ..++|+|..+...+       .+..+.+..++.
T Consensus        60 ~~l~~-------------------~~~d~ii~~~~~~~~~~~-~~~-~~~ipvv~~~~~~~-------~~~~~~v~~d~~  111 (289)
T 3K9C_B           60 QALMR-------------------ERCEAAILLGTRFDTDEL-GAL-ADRVPALVVARASG-------LPGVGAVRGDDV  111 (289)
T ss_dssp             HHHHT-------------------TTEEEEEEETCCCCHHHH-HHH-HTTSCEEEESSCCC-------STTSEEEEECHH
T ss_pred             HHHHh-------------------CCCCEEEEECCCCCHHHH-HHH-hcCCCEEEEeccCC-------CCCCcEEEeCcH
Confidence            33332                   478888876543332222 233 46899888765432       134566777777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAV  278 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~vi  278 (908)
                      ..++.+++++.+.+.++++++... +.++..+.++|++.+++. ++.+....... ..+..+....++++++. .++|+|
T Consensus       112 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~d~i  189 (289)
T 3K9C_B          112 AGITLAVDHLTELGHRNIAHIDGADAPGGADRRAGFLAAMDRH-GLSASATVVTG-GTTETEGAEGMHTLLEMPTPPTAV  189 (289)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEEECTTSTTHHHHHHHHHHHHHHT-TCGGGEEEEEC-CSSHHHHHHHHHHHHHSSSCCSEE
T ss_pred             HHHHHHHHHHHHCCCCcEEEeeCCCCCChHHHHHHHHHHHHHc-CCCCCCcEEeC-CCChHHHHHHHHHHhcCCCCCCEE
Confidence            777788888766678899999853 345667778888887764 34433211111 01112233445555421 247887


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       190 ~~~~-~~~a~~~~~~l~~~g~~  210 (289)
T 3K9C_B          190 VAFN-DRCATGVLDLLVRSGRD  210 (289)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHCCCC
Confidence            7664 44566778888877764


No 248
>4RY8_B Periplasmic binding protein/LacI transcriptional regulator; SUGAR TRANSPORTER, ENZYME FUNCTION INITIATIVE; HET: SR1; 1.75A {Thermotoga lettingae TMO}
Probab=96.95  E-value=1.7e-06  Score=88.41  Aligned_cols=215  Identities=9%  Similarity=0.041  Sum_probs=118.1  Template_Neff=11.300

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++.++||++.|..+.            .++.....+++.++++.+          +++.+.+...++    +...+.
T Consensus        10 ~~~~~~~~Igv~~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~   63 (329)
T 4RY8_B           10 FENPKNVRIALVREVGEG------------SFFERYLAGAQSMARELG----------VTLLEATAHGDM----ARMVTM   63 (329)
T ss_dssp             GGSGGGCEEEEEESCCCS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCH----HHHHHH
T ss_pred             cCCCCCcEEEEEEeCCCC------------hHHHHHHHHHHHHHHHhC----------CEEEEEeCCCCH----HHHHHH
Confidence            456678999999997542            245667778888877642          334444543332    122333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+.. .......+...++|+|..+...+       .+.++.+.++
T Consensus        64 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d  117 (329)
T 4RY8_B           64 IENFIT-------------------QRVDAIIIDHGRPDPLMPKIKEALDRGIRVVTFDLVVD-------DNRVPEIEQD  117 (329)
T ss_dssp             HHHHHH-------------------TTCSEEEEESCCHHHHHHHHHHHHHHTCEEEEESCCCS-------CTTSCEEECC
T ss_pred             HHHHHh-------------------cCCCEEEECCCCccccHHHHHHHHHCCCEEEEECCCCC-------CCCCcEEecC
Confidence            443332                   47887776443332 22344556778999998776432       2345667777


Q NP_000836.2     199 DSYQAQAMVDIVTA--LGWNYVSTLASEGNYGESGVEAFTQISREI-GGVCIAQSQK-IPREPRPGEFEKIIKRLLE-TP  273 (908)
Q Consensus       199 ~~~~~~~~~~~l~~--~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-~~i~v~~~~~-~~~~~~~~~~~~~~~~l~~-~~  273 (908)
                      ....++.+++++.+  .+.++++++..+..++......+.+.+.+. .++.+..... ... .+..+....++++++ ..
T Consensus       118 ~~~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~l~~~~  196 (329)
T 4RY8_B          118 DLLIGYLISKQLAVDFAGNANVIYVNVGGFAPLDKRDKMWQIIKWRFPGIKEVAKIGAVTG-STAADTQTRMEAAMKEKP  196 (329)
T ss_dssp             HHHHHHHHHHHHHHHTTTCEEEEEECCSSSHHHHHHHHHHHHHHHHCTTEEEEEEECCCCS-SHHHHHHHHHHHHHHHCT
T ss_pred             hHHHHHHHHHHHHHHcCCCceEEEEEcCCCccHHHHHHHHHHHHHHCCCcEEEEEEcCCCC-CCHHHHHHHHHHHHHHCC
Confidence            77777788877755  577899998754434433444444444331 1233321110 110 111233344555542 12


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++++|++.. +..+..+++++++.|+..++.+++.
T Consensus       197 ~~~~I~~~~-~~~a~~~~~al~~~g~~~~v~v~~~  230 (329)
T 4RY8_B          197 EANAVLAMW-DEFAKGAVRAIMQAGKSDQFKVYSV  230 (329)
T ss_dssp             TCCEEEESS-HHHHHHHHHHHHHHTCGGGCEEEEE
T ss_pred             CCCEEEEcC-hHHHHHHHHHHHHcCCCCceEEEEe
Confidence            467776553 4456678888887776423334443


No 249
>4RY8_C Periplasmic binding protein/LacI transcriptional regulator; SUGAR TRANSPORTER, ENZYME FUNCTION INITIATIVE; HET: SR1; 1.75A {Thermotoga lettingae TMO}
Probab=96.95  E-value=1.7e-06  Score=88.41  Aligned_cols=215  Identities=9%  Similarity=0.041  Sum_probs=117.0  Template_Neff=11.300

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++.++||++.|..+.            .++.....+++.++++.+          +++.+.+...++    +...+.
T Consensus        10 ~~~~~~~~Igv~~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~   63 (329)
T 4RY8_C           10 FENPKNVRIALVREVGEG------------SFFERYLAGAQSMARELG----------VTLLEATAHGDM----ARMVTM   63 (329)
T ss_dssp             C--CTTCEEEEEESCCCS------------HHHHHHHHHHHHHHHHHT----------CEEEEEECTTCH----HHHHHH
T ss_pred             cCCCCCcEEEEEEeCCCC------------hHHHHHHHHHHHHHHHhC----------CEEEEEeCCCCH----HHHHHH
Confidence            456678999999997542            245667778888877642          334444543332    122333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+.. .......+...++|+|..+...+       .+.++.+.++
T Consensus        64 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d  117 (329)
T 4RY8_C           64 IENFIT-------------------QRVDAIIIDHGRPDPLMPKIKEALDRGIRVVTFDLVVD-------DNRVPEIEQD  117 (329)
T ss_dssp             HHHHHH-------------------TTCSEEEEESCCHHHHHHHHHHHHHTTCEEEEESCCCS-------CTTSCEEECC
T ss_pred             HHHHHh-------------------cCCCEEEECCCCccccHHHHHHHHHCCCEEEEECCCCC-------CCCCcEEecC
Confidence            443332                   47887776443332 22344556778999998776432       2345667777


Q NP_000836.2     199 DSYQAQAMVDIVTA--LGWNYVSTLASEGNYGESGVEAFTQISREI-GGVCIAQSQK-IPREPRPGEFEKIIKRLLE-TP  273 (908)
Q Consensus       199 ~~~~~~~~~~~l~~--~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~-~~i~v~~~~~-~~~~~~~~~~~~~~~~l~~-~~  273 (908)
                      ....++.+++++.+  .+.++++++..+..++......+.+.+.+. .++.+..... ... .+..+....++++++ ..
T Consensus       118 ~~~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~l~~~~  196 (329)
T 4RY8_C          118 DLLIGYLISKQLAVDFAGNANVIYVNVGGFAPLDKRDKMWQIIKWRFPGIKEVAKIGAVTG-STAADTQTRMEAAMKEKP  196 (329)
T ss_dssp             HHHHHHHHHHHHHHHTTTCEEEEEECCSSCHHHHHHHHHHHHHHHHCTTEEEEEEECCCCS-SHHHHHHHHHHHHHHHCT
T ss_pred             hHHHHHHHHHHHHHHcCCCceEEEEEcCCCccHHHHHHHHHHHHHHCCCcEEEEEEcCCCC-CCHHHHHHHHHHHHHHCC
Confidence            77777788877755  577899998754434433444444444331 1233321110 110 111233344555542 12


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++++|++.. +..+..+++++++.|+..++.+++.
T Consensus       197 ~~~~I~~~~-~~~a~~~~~al~~~g~~~~v~v~~~  230 (329)
T 4RY8_C          197 EANAVLAMW-DEFAKGAVRAIMQAGKSDQFKVYSV  230 (329)
T ss_dssp             TCCEEEESS-HHHHHHHHHHHHHHTCGGGCEEEEE
T ss_pred             CCCEEEEcC-hHHHHHHHHHHHHcCCCCceEEEEe
Confidence            467776553 4456678888887776423334443


No 250
>3ROT_A ABC sugar transporter, periplasmic sugar; NYSGRC, PSI-BIOLOGY, Structural Genomics, New; HET: GOL; 1.91A {Legionella pneumophila subsp. pneumophila}
Probab=96.93  E-value=1.9e-06  Score=86.61  Aligned_cols=205  Identities=8%  Similarity=0.085  Sum_probs=118.1  Template_Neff=11.400

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      .+++||++.|....            .++.....+++.++++.        |+++.+...|+..++    +...+.++++
T Consensus         2 ~~~~I~vi~~~~~~------------~~~~~~~~g~~~a~~~~--------g~~v~~~~~~~~~~~----~~~~~~~~~l   57 (297)
T 3ROT_A            2 VRDKYYLITHGSQD------------PYWTSLFQGAKKAAEEL--------KVDLQILAPPGANDV----PKQVQFIESA   57 (297)
T ss_dssp             -CCEEEEECSCCCS------------HHHHHHHHHHHHHHHHH--------TCEEEEECCSSSCCH----HHHHHHHHHH
T ss_pred             CCcEEEEEccCCCC------------HHHHHHHHHHHHHHHHh--------CCEEEEECCCCCCCH----HHHHHHHHHH
Confidence            46789999985332            24566778888888775        345655555433332    2233344443


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAA-ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      +.                   .+++++|+.. .+.........+...++|+|..+...+...   ..++++++.+++...
T Consensus        58 ~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~---~~~~~~~v~~d~~~~  115 (297)
T 3ROT_A           58 LA-------------------TYPSGIATTIPSDTAFSKSLQRANKLNIPVIAVDTRPKDKT---KNPYLVFLGSDNLLA  115 (297)
T ss_dssp             HH-------------------TCCSEEEECCCCSSTTHHHHHHHHHHTCCEEEESCCCSCTT---TSCCSCEEECCHHHH
T ss_pred             HH-------------------hCCCEEEEeCCChHHHHHHHHHHHHCCCCEEEEcCCCCCCC---CCCceeEEeCChHHH
Confidence            32                   4788777643 222222445556678999998776543211   124567777777777


Q NP_000836.2     203 AQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       203 ~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ++.+++++.+.  +.++++++..  ++.++..+.+++++.+++. ++.+... ...  .+..+....+++++.. .++++
T Consensus       116 ~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-g~~~~~~-~~~--~~~~~~~~~~~~~~~~~~~~~~  191 (297)
T 3ROT_A          116 GKKLGEKALELTPSAKRALVLNPQPGHIGLEKRAYGIKTILQDK-GIFFEEL-DVG--TDPNQVQSRVKSYFKIHPETNI  191 (297)
T ss_dssp             HHHHHHHHHHHCTTCCEEEEEESCTTCHHHHHHHHHHHHHHHHT-TCEEEEE-ECC--SCHHHHHHHHHHHHHHCTTCCE
T ss_pred             HHHHHHHHHHhCCCCCeEEEEcCCCCchhHHHHHHHHHHHHHhc-CCeEEEE-eCC--CCHHHHHHHHHHHHHHCCCccE
Confidence            88888887665  6789999975  3345667778888888765 3444321 111  1122333445555421 23566


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      |++.. +..+..+++++++.|.
T Consensus       192 i~~~~-~~~a~~~~~~~~~~g~  212 (297)
T 3ROT_A          192 IFCLT-SQALDPLGQMLLHPDR  212 (297)
T ss_dssp             EEESS-HHHHHHHHHHHHSHHH
T ss_pred             EEECC-hhhhHHHHHHhhCCCC
Confidence            65553 3445566666666553


No 251
>3ROT_B ABC sugar transporter, periplasmic sugar; NYSGRC, PSI-BIOLOGY, Structural Genomics, New; HET: MSE, GOL; 1.91A {Legionella pneumophila subsp. pneumophila}
Probab=96.93  E-value=1.9e-06  Score=86.61  Aligned_cols=205  Identities=8%  Similarity=0.085  Sum_probs=118.1  Template_Neff=11.400

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      .+++||++.|....            .++.....+++.++++.        |+++.+...|+..++    +...+.++++
T Consensus         2 ~~~~I~vi~~~~~~------------~~~~~~~~g~~~a~~~~--------g~~v~~~~~~~~~~~----~~~~~~~~~l   57 (297)
T 3ROT_B            2 VRDKYYLITHGSQD------------PYWTSLFQGAKKAAEEL--------KVDLQILAPPGANDV----PKQVQFIESA   57 (297)
T ss_dssp             -CCEEEEECSCCSS------------HHHHHHHHHHHHHHHHH--------TCEEEEECCSSSCCH----HHHHHHHHHH
T ss_pred             CCcEEEEEccCCCC------------HHHHHHHHHHHHHHHHh--------CCEEEEECCCCCCCH----HHHHHHHHHH
Confidence            46789999985332            24566778888888775        345655555433332    2233344443


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAA-ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      +.                   .+++++|+.. .+.........+...++|+|..+...+...   ..++++++.+++...
T Consensus        58 ~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~---~~~~~~~v~~d~~~~  115 (297)
T 3ROT_B           58 LA-------------------TYPSGIATTIPSDTAFSKSLQRANKLNIPVIAVDTRPKDKT---KNPYLVFLGSDNLLA  115 (297)
T ss_dssp             HT-------------------TCCSEEEECCCCSSSSHHHHHHHHHTTCCEEEESCCCSCTT---TSCCSCEEECCHHHH
T ss_pred             HH-------------------hCCCEEEEeCCChHHHHHHHHHHHHCCCCEEEEcCCCCCCC---CCCceeEEeCChHHH
Confidence            32                   4788777643 222222445556678999998776543211   124567777777777


Q NP_000836.2     203 AQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARA  277 (908)
Q Consensus       203 ~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~v  277 (908)
                      ++.+++++.+.  +.++++++..  ++.++..+.+++++.+++. ++.+... ...  .+..+....+++++.. .++++
T Consensus       116 ~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-g~~~~~~-~~~--~~~~~~~~~~~~~~~~~~~~~~  191 (297)
T 3ROT_B          116 GKKLGEKALELTPSAKRALVLNPQPGHIGLEKRAYGIKTILQDK-GIFFEEL-DVG--TDPNQVQSRVKSYFKIHPETNI  191 (297)
T ss_dssp             HHHHHHHHHHHCTTCCEEEEEESSTTCHHHHHHHHHHHHHHHHT-TCEEEEE-ECC--SCHHHHHHHHHHHHHHCTTCCE
T ss_pred             HHHHHHHHHHhCCCCCeEEEEcCCCCchhHHHHHHHHHHHHHhc-CCeEEEE-eCC--CCHHHHHHHHHHHHHHCCCccE
Confidence            88888887665  6789999975  3345667778888888765 3444321 111  1122333445555421 23566


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      |++.. +..+..+++++++.|.
T Consensus       192 i~~~~-~~~a~~~~~~~~~~g~  212 (297)
T 3ROT_B          192 IFCLT-SQALDPLGQMLLHPDR  212 (297)
T ss_dssp             EEESS-HHHHHHHHHHHHSHHH
T ss_pred             EEECC-hhhhHHHHHHhhCCCC
Confidence            65553 3445566666666553


No 252
>5BRA_A Putative periplasmic binding protein with; Periplasmic solute binding Protein, ENZYME; HET: MSE; 2.971A {Ochrobactrum anthropi (strain ATCC 49188 / DSM 6882 / NCTC 12168)}
Probab=96.93  E-value=1.9e-06  Score=89.01  Aligned_cols=220  Identities=8%  Similarity=-0.032  Sum_probs=122.4  Template_Neff=10.800

Q NP_000836.2      37 AHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQS  116 (908)
Q Consensus        37 ~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~  116 (908)
                      .......+.++||++.|..+.            .++.....+++.++++.+        +++.+...+. .++    +..
T Consensus        36 ~~~~~~~~~~~Igvv~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~v~~~~~~~-~~~----~~~   90 (350)
T 5BRA_A           36 LITTANDKKYTIATVVKVDGI------------AWFDRMRDGVDQFKADTG--------NDVWMVGPSQ-ADA----AAQ   90 (350)
T ss_pred             HHHhhcCCCeEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC--------CEEEEEeCCC-CCH----HHH
Confidence            344556788999999997542            255677888888887763        3444432222 222    223


Q NP_000836.2     117 LTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRV  195 (908)
Q Consensus       117 ~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~  195 (908)
                      .+.+++++.                   .+++++|+...+.. .......+.+.++|+|..+...+.      ...++++
T Consensus        91 ~~~~~~l~~-------------------~~~d~iI~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v  145 (350)
T 5BRA_A           91 VQIVENLIA-------------------QGVDAIAIVPFSVEAVEPVLKKARERGIVVISHEASNIQ------NVDYDIE  145 (350)
T ss_pred             HHHHHHHHH-------------------CCCCEEEECCCChHHHHHHHHHHHHCCCCEEEeCCCCCC------CCCeEEE
Confidence            334444332                   47888776543322 224455667789999877654321      1334556


Q NP_000836.2     196 VPPDSYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLL  270 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~  270 (908)
                      .+++...+..+++++.+.  +.++++++..  ++.++..+.+++++.+++.+ ++.+.... .....+..+....+++++
T Consensus       146 ~~d~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~l  224 (350)
T 5BRA_A          146 AFDNKAYGANLMKELGKSMGGKGKYVTTVGSLTSKSQMEWIDGAVEYQKANFPEMSEATGR-LETYDDANTDYNKLKEAM  224 (350)
T ss_pred             CCCHHHHHHHHHHHHHHHhCCCcEEEEEeCCCCCHHHHHHHHHHHHHHHHHCCCeEEEEee-cCCCCCHHHHHHHHHHHH
Confidence            667666677777777543  5788999885  34456667778887776531 13322110 000011123334455554


Q NP_000836.2     271 ET-PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       271 ~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      +. .++++|++.. +..+..+++++++.|+..++.+++.
T Consensus       225 ~~~~~~~~i~~~~-~~~a~~~~~al~~~g~~~~v~v~g~  262 (350)
T 5BRA_A          225 TAYPDITGILGAP-MPTSAGAGRLIAEGGLKGKVFFAGT  262 (350)
T ss_pred             HHCCCCCEEEEcC-hhHHHHHHHHHHHCCCCCCeEEEEe
Confidence            21 2456665543 4456678888888776423344443


No 253
>2H3H_A Sugar ABC transporter, periplasmic sugar-binding; glucose binding protein, periplasmic binding; HET: BGC; 1.7A {Thermotoga maritima}
Probab=96.93  E-value=1.9e-06  Score=87.35  Aligned_cols=209  Identities=10%  Similarity=0.057  Sum_probs=113.2  Template_Neff=11.300

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|.+.             .++.....+++.++++.+        +++.+...+ ..++    +...+.+++++
T Consensus         1 ~~~Ig~i~~~~~-------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~-~~~~----~~~~~~~~~l~   54 (313)
T 2H3H_A            1 MLTIGVIGKSVH-------------PYWSQVEQGVKAAGKALG--------VDTKFFVPQ-KEDI----NAQLQMLESFI   54 (313)
T ss_dssp             CCEEEEECSCSS-------------HHHHHHHHHHHHHHHHHT--------CEEEEECCS-SSCH----HHHHHHHHHHH
T ss_pred             CeEEEEEcCCCC-------------hHHHHHHHHHHHHHHHhC--------CEEEEECCC-ccCH----HHHHHHHHHHH
Confidence            367899998642             245667788888887753        333332211 1221    12233344333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++|+...+... ......+...++|+|..+...+.      .++++++.+++...+
T Consensus        55 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~~~~  109 (313)
T 2H3H_A           55 A-------------------EGVNGIAIAPSDPTAVIPTIKKALEMGIPVVTLDTDSPD------SGRYVYIGTDNYQAG  109 (313)
T ss_dssp             H-------------------TTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCTT------SCCSCEEECCHHHHH
T ss_pred             H-------------------cCCCEEEECCCChHhhHHHHHHHHHCCCCEEEECCCCCC------CCcceEEeCChHHHH
Confidence            2                   477877764433322 23445567789999887654321      234566777777777


Q NP_000836.2     204 QAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       204 ~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      +.+++++.+.  +.++++++..  ++.++..+.++|.+.+++. ++.+.......  .+..+....++++++ ..++++|
T Consensus       110 ~~~~~~l~~~~~g~~~i~~~~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~ai  186 (313)
T 2H3H_A          110 YTAGLIMKELLGGKGKVVIGTGSLTAMNSLQRIQGFKDAIKDS-EIEIVDILNDE--EDGARAVSLAEAALNAHPDLDAF  186 (313)
T ss_dssp             HHHHHHHHHHHTSCSEEEEEESCSSCHHHHHHHHHHHHHHTTS-SCEEEEEEECS--SCHHHHHHHHHHHHHHCTTCCEE
T ss_pred             HHHHHHHHHHhCCCeEEEEEeCCCCchHHHHHHHHHHHHHhcC-CcEEEEEEcCC--CCHHHHHHHHHHHHHHCCCCCEE
Confidence            7888877654  6788988875  3345667788888887764 34433211111  111122333445442 1257777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++... .....++.++++.+...++.+++.
T Consensus       187 ~~~~~-~~~~~~~~~~~~~~~~~~v~iig~  215 (313)
T 2H3H_A          187 FGVYA-YNGPAQALVVKNAGKVGKVKIVCF  215 (313)
T ss_dssp             EECST-THHHHHHHHHHHTTCTTTSEEEEE
T ss_pred             EEcCC-CChHHHHHHHHHCCCCCCeEEEEe
Confidence            66542 233444555555554323334433


No 254
>2H3H_B Sugar ABC transporter, periplasmic sugar-binding; glucose binding protein, periplasmic binding; HET: BGC; 1.7A {Thermotoga maritima}
Probab=96.93  E-value=1.9e-06  Score=87.35  Aligned_cols=209  Identities=10%  Similarity=0.057  Sum_probs=113.2  Template_Neff=11.300

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|.+.             .++.....+++.++++.+        +++.+...+ ..++    +...+.+++++
T Consensus         1 ~~~Ig~i~~~~~-------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~-~~~~----~~~~~~~~~l~   54 (313)
T 2H3H_B            1 MLTIGVIGKSVH-------------PYWSQVEQGVKAAGKALG--------VDTKFFVPQ-KEDI----NAQLQMLESFI   54 (313)
T ss_dssp             CCEEEEECSCSS-------------HHHHHHHHHHHHHHHHHT--------CEEEEECCS-SCCH----HHHHHHHHHHH
T ss_pred             CeEEEEEcCCCC-------------hHHHHHHHHHHHHHHHhC--------CEEEEECCC-ccCH----HHHHHHHHHHH
Confidence            367899998642             245667788888887753        333332211 1221    12233344333


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++|+...+... ......+...++|+|..+...+.      .++++++.+++...+
T Consensus        55 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~~~~  109 (313)
T 2H3H_B           55 A-------------------EGVNGIAIAPSDPTAVIPTIKKALEMGIPVVTLDTDSPD------SGRYVYIGTDNYQAG  109 (313)
T ss_dssp             H-------------------HTCSEEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCTT------SCCSCEEECCHHHHH
T ss_pred             H-------------------cCCCEEEECCCChHhhHHHHHHHHHCCCCEEEECCCCCC------CCcceEEeCChHHHH
Confidence            2                   477877764433322 23445567789999887654321      234566777777777


Q NP_000836.2     204 QAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       204 ~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      +.+++++.+.  +.++++++..  ++.++..+.++|.+.+++. ++.+.......  .+..+....++++++ ..++++|
T Consensus       110 ~~~~~~l~~~~~g~~~i~~~~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~ai  186 (313)
T 2H3H_B          110 YTAGLIMKELLGGKGKVVIGTGSLTAMNSLQRIQGFKDAIKDS-EIEIVDILNDE--EDGARAVSLAEAALNAHPDLDAF  186 (313)
T ss_dssp             HHHHHHHHHHTTTEEEEEEEESCSSSHHHHHHHHHHHHHTTTS-EEEEEEEEECS--SCHHHHHHHHHHHHHHCTTCCEE
T ss_pred             HHHHHHHHHHhCCCeEEEEEeCCCCchHHHHHHHHHHHHHhcC-CcEEEEEEcCC--CCHHHHHHHHHHHHHHCCCCCEE
Confidence            7888877654  6788988875  3345667788888887764 34433211111  111122333445442 1257777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++... .....++.++++.+...++.+++.
T Consensus       187 ~~~~~-~~~~~~~~~~~~~~~~~~v~iig~  215 (313)
T 2H3H_B          187 FGVYA-YNGPAQALVVKNAGKVGKVKIVCF  215 (313)
T ss_dssp             EECST-THHHHHHHHHHHTTCBTTBEEEEE
T ss_pred             EEcCC-CChHHHHHHHHHCCCCCCeEEEEe
Confidence            66542 233444555555554323334433


No 255
>3GBV_A Putative LacI-family transcriptional regulator; NYSGXRC, PSI-II, 11231j, transcriptional regulator; HET: EDO; 2.2A {Bacteroides fragilis}
Probab=96.93  E-value=1.9e-06  Score=86.77  Aligned_cols=155  Identities=18%  Similarity=0.140  Sum_probs=94.8  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++.++||++.|.+...           .++.....+++.++++.|..     +.++++...|.. ++    ....+.++
T Consensus         5 ~~~~~~Ig~i~~~~~~~-----------~~~~~~~~g~~~~~~~~~~~-----~~~i~~~~~~~~-~~----~~~~~~~~   63 (304)
T 3GBV_A            5 SNKKYTFACLLPKHLEG-----------EYWTDVQKGIREAVTTYSDF-----NISANITHYDPY-DY----NSFVATSQ   63 (304)
T ss_dssp             --CCEEEEEEEECCCTT-----------SHHHHHHHHHHHHHHHTGGG-----CEEEEEEEECSS-CH----HHHHHHHH
T ss_pred             cCCCeEEEEEccccCCC-----------hhHHHHHHHHHHHHHhhhhc-----CeEEEEecCCCC-CH----HHHHHHHH
Confidence            45789999999864321           25567888999998887632     234444444432 22    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +++.                   +++|++|....+.. .......+...++|+|..+...+.      .++++.+.++..
T Consensus        64 ~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  118 (304)
T 3GBV_A           64 AVIE-------------------EQPDGVMFAPTVPQYTKGFTDALNELGIPYIYIDSQIKD------APPLAFFGQNSH  118 (304)
T ss_dssp             HHHT-------------------TCCSEEEECCSSGGGTHHHHHHHHHHTCCEEEESSCCTT------SCCSEEEECCHH
T ss_pred             HHHH-------------------hCCCEEEECCCChhhhHHHHHHHHHcCCCEEEEcCCCCC------CCCcEEEcCChH
Confidence            4332                   46787765433322 223345566789999987764431      235667777777


Q NP_000836.2     201 YQAQAMVDIVTAL--GWNYVSTLAS------EGNYGESGVEAFTQISREI  242 (908)
Q Consensus       201 ~~~~~~~~~l~~~--~~~~v~ii~~------~~~~~~~~~~~~~~~~~~~  242 (908)
                      ..++.+++++.+.  +.++++++..      +..++..+.+++++.+++.
T Consensus       119 ~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~  168 (304)
T 3GBV_A          119 QSGYFAARMLMLLAVNDREIVIFRKIHEGVIGSNQQESREIGFRQYMQEH  168 (304)
T ss_dssp             HHHHHHHHHHHHHSTTCSEEEEEEEEBTTBCCCHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHccCCCeEEEEEeccCCCCCChHHHHHHHHHHHHHHHH
Confidence            7788888887654  7789999873      2345566778888877664


No 256
>3HUU_A Transcription regulator like protein; PSI-II, NYSGXRC, 11235m, transcription regulator; 1.95A {Staphylococcus haemolyticus}
Probab=96.89  E-value=2.3e-06  Score=86.17  Aligned_cols=205  Identities=13%  Similarity=0.116  Sum_probs=115.7  Template_Neff=11.800

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++..+||++.|.++....       ...++.....+++.++++.+        +  ++.+.+...++    +...+.+
T Consensus        18 ~~~~~~~Ig~i~~~~~~~~~-------~~~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~   76 (305)
T 3HUU_A           18 ITNKTLTIGLIQKSSAPEIR-------QNPFNSDVLNGINQACNVRG--------Y--STRMTVSENSG----DLYHEVK   76 (305)
T ss_dssp             ---CCCEEEEECSCCSHHHH-------TSHHHHHHHHHHHHHHHHHT--------C--EEEECCCSSHH----HHHHHHH
T ss_pred             HcCCCcEEEEEEcCCChhHh-------cCccHHHHHHHHHHHHHHhC--------C--eEEEEEcCCCc----chHHHHH
Confidence            34678999999987642100       01345667788888777642        3  33334433321    1222233


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +.+..                   +++|++|+...+.. ......+...++|+|..+...+       .+.++++.++..
T Consensus        77 ~~~~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~  129 (305)
T 3HUU_A           77 TMIQS-------------------KSVDGFILLYSLKD-DPIEHLLNEFKVPYLIVGKSLN-------YENIIHIDNDNI  129 (305)
T ss_dssp             HHHHT-------------------TCCSEEEESSCBTT-CHHHHHHHHTTCCEEEESCCCS-------STTCCEEECCHH
T ss_pred             HHHHh-------------------CCCCEEEEeccCCC-ChHHHHHHHcCCCEEEECCCCC-------CCCCcEEecChH
Confidence            32221                   47888886554433 2445566778999998765432       134566777777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL--ETPNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~--~~~~~~  276 (908)
                      ..++.+++++.+.+.++++++.....  ....+.++|++.+++. ++.+.... ..   +..+....+++++  ...++|
T Consensus       130 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~-~~---~~~~~~~~~~~~~~~~~~~~d  204 (305)
T 3HUU_A          130 DAAYQLTQYLYHLGHRHILFLQESGHYAVTEDRSVGFKQYCDDV-KISNDCVV-IK---SMNDLRDFIKQYCIDASHMPS  204 (305)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEEEESSCBHHHHHHHHHHHHHHHHT-TCCCCEEE-EC---SHHHHHHHC--------CCCS
T ss_pred             HHHHHHHHHHHHcCCCeEEEEeCCCCchhHHHHHHHHHHHHHHc-CCCcceEE-Ec---chhhHHHHHHHHHHHcCCCCc
Confidence            77888888887678889999985432  3466778888887764 34332111 11   1123334444442  123678


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      +|++.. +..+..+++++++.|+
T Consensus       205 ~i~~~~-~~~a~~~~~~l~~~g~  226 (305)
T 3HUU_A          205 VIITSD-VMLNMQLLNVLYEYQL  226 (305)
T ss_dssp             EEEESS-HHHHHHHHHHHHHTTC
T ss_pred             EEEECC-HHHHHHHHHHHHHcCC
Confidence            775553 4456778888887776


No 257
>3HUU_C Transcription regulator like protein; PSI-II, NYSGXRC, 11235m, transcription regulator; 1.95A {Staphylococcus haemolyticus}
Probab=96.89  E-value=2.3e-06  Score=86.17  Aligned_cols=205  Identities=13%  Similarity=0.116  Sum_probs=116.7  Template_Neff=11.800

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++..+||++.|.++....       ...++.....+++.++++.+        +  ++.+.+...++    +...+.+
T Consensus        18 ~~~~~~~Ig~i~~~~~~~~~-------~~~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~   76 (305)
T 3HUU_C           18 ITNKTLTIGLIQKSSAPEIR-------QNPFNSDVLNGINQACNVRG--------Y--STRMTVSENSG----DLYHEVK   76 (305)
T ss_dssp             ---CCCEEEEECSCCCHHHH-------TSHHHHHHHHHHHHHHHHTT--------C--EEEECCCSSHH----HHHHHHH
T ss_pred             HcCCCcEEEEEEcCCChhHh-------cCccHHHHHHHHHHHHHHhC--------C--eEEEEEcCCCc----chHHHHH
Confidence            34678999999987642100       01345667788888777642        3  33334433321    1222233


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +.+..                   +++|++|+...+.. ......+...++|+|..+...+       .+.++++.++..
T Consensus        77 ~~~~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~  129 (305)
T 3HUU_C           77 TMIQS-------------------KSVDGFILLYSLKD-DPIEHLLNEFKVPYLIVGKSLN-------YENIIHIDNDNI  129 (305)
T ss_dssp             HHHHT-------------------TCCSEEEESSCBTT-CHHHHHHHHTTCCEEEESCCCS-------CSSCCEEECCHH
T ss_pred             HHHHh-------------------CCCCEEEEeccCCC-ChHHHHHHHcCCCEEEECCCCC-------CCCCcEEecChH
Confidence            32221                   47888886554433 2445566778999998765432       134566777777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL--ETPNAR  276 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~--~~~~~~  276 (908)
                      ..++.+++++.+.+.++++++.....  ....+.++|++.+++. ++.+.... ..   +..+....+++++  ...++|
T Consensus       130 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~-~~---~~~~~~~~~~~~~~~~~~~~d  204 (305)
T 3HUU_C          130 DAAYQLTQYLYHLGHRHILFLQESGHYAVTEDRSVGFKQYCDDV-KISNDCVV-IK---SMNDLRDFIKQYCIDASHMPS  204 (305)
T ss_dssp             HHHHHHHHHHHHHTCCCEEEEEESSCBHHHHHHHHHHHHHHHHT-TCCCCEEE-EC---SHHHHHHHHTTC------CCS
T ss_pred             HHHHHHHHHHHHcCCCeEEEEeCCCCchhHHHHHHHHHHHHHHc-CCCcceEE-Ec---chhhHHHHHHHHHHHcCCCCc
Confidence            77888888887678889999985432  3466778888887764 34332111 11   1123334444442  123678


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      +|++.. +..+..+++++++.|+
T Consensus       205 ~i~~~~-~~~a~~~~~~l~~~g~  226 (305)
T 3HUU_C          205 VIITSD-VMLNMQLLNVLYEYQL  226 (305)
T ss_dssp             EEEESS-HHHHHHHHHHHHHTTC
T ss_pred             EEEECC-HHHHHHHHHHHHHcCC
Confidence            775553 4456778888887776


No 258
>3KKE_C LacI family Transcriptional regulator; STRUCTURAL GENOMICS, TRANSCRIPTION, DNA-binding, Transcription; HET: ACT; 2.2A {Mycobacterium smegmatis str. MC2 155}
Probab=96.87  E-value=2.5e-06  Score=85.91  Aligned_cols=205  Identities=12%  Similarity=0.124  Sum_probs=117.5  Template_Neff=11.700

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++..+||++.|..+.            .++..+..+++.++++.        |++  +.+.+.. +.    ....+.
T Consensus        10 l~~~~~~~I~~v~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~--~~~~~~~-~~----~~~~~~   62 (303)
T 3KKE_C           10 LRHSRSGTIGLIVPDVNN------------AVFADMFSGVQMAASGH--------STD--VLLGQID-AP----PRGTQQ   62 (303)
T ss_dssp             CCTTCSCEEEEECSCTTS------------TTHHHHHHHHHHHHHHT--------TCE--EEEECCC-ST----THHHHH
T ss_pred             HhcCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHhcC--------CCE--EEEEeCC-CC----hhHHHH
Confidence            345678999999987542            24566777887777664        233  3333322 21    112223


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +.+++.                  ..++|++|+...+.........+ ..++|+|..+...+        +..+.+..++
T Consensus        63 ~~~~~~------------------~~~~d~ii~~~~~~~~~~~~~~~-~~~ipvv~~~~~~~--------~~~~~v~~d~  115 (303)
T 3KKE_C           63 LSRLVS------------------EGRVDGVLLQRREDFDDDMLAAV-LEGVPAVTINSRVP--------GRVGSVILDD  115 (303)
T ss_dssp             HHHHHH------------------TTSCSEEEEECCTTCCHHHHHHH-HTTSCEEEESCCCT--------TSCCEEEECH
T ss_pred             HHHHHH------------------cCCCCEEEEeccccCCHHHHHHH-HhCCCEEEeCCCCC--------CCCCEEEeCc
Confidence            333322                  14688888654433222333444 67999998776432        1355677777


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE------  271 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~------  271 (908)
                      ...++.+++++.+.+.++++++..+.  .....+.++|++.+++. ++.+.....+..+.+..+..+.++++++      
T Consensus       116 ~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~  194 (303)
T 3KKE_C          116 QKGGGIATEHLITLGHSRIAFISGTAIHDTAQRRKEGYLETLASA-GLRSEAAWVVDAGWEADAGSAALNTLYRGANLGK  194 (303)
T ss_dssp             HHHHHHHHHHHHHHTCCCEEEECSCTTCHHHHHHHHHHHHHHHHH-TCCCCGGGEECCCSSHHHHHHHHHHHHHHSCTTS
T ss_pred             hHHHHHHHHHHHHcCCCcEEEEeCCCCChHHHHHHHHHHHHHHHc-CCCCCceeEEecCCChHHHHHHHHHHHhhcCCCC
Confidence            77888888888777888999998543  35566778888888765 3332211111100111223344444432      


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ..++++|++.. +..+..+++++++.|+.
T Consensus       195 ~~~~~~i~~~~-~~~a~~~~~a~~~~g~~  222 (303)
T 3KKE_C          195 PDGPTAVVVAS-VNAAVGALSTALRLGLR  222 (303)
T ss_dssp             TTSCSEEEESS-HHHHHHHHHHHHHHTCC
T ss_pred             CCCCCEEEECC-HHHHHHHHHHHHHCCCC
Confidence            13577777664 44566778888877763


No 259
>3KKE_B LacI family Transcriptional regulator; STRUCTURAL GENOMICS, TRANSCRIPTION, DNA-binding, Transcription; HET: ACT; 2.2A {Mycobacterium smegmatis str. MC2 155}
Probab=96.87  E-value=2.5e-06  Score=85.91  Aligned_cols=205  Identities=12%  Similarity=0.124  Sum_probs=117.5  Template_Neff=11.700

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++..+||++.|..+.            .++..+..+++.++++.        |++  +.+.+.. +.    ....+.
T Consensus        10 l~~~~~~~I~~v~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~--~~~~~~~-~~----~~~~~~   62 (303)
T 3KKE_B           10 LRHSRSGTIGLIVPDVNN------------AVFADMFSGVQMAASGH--------STD--VLLGQID-AP----PRGTQQ   62 (303)
T ss_dssp             HHHTCCSEEEEECSCTTS------------TTHHHHHHHHHHHHHHT--------TCE--EEEECCC-ST----THHHHH
T ss_pred             HhcCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHhcC--------CCE--EEEEeCC-CC----hhHHHH
Confidence            345678999999987542            24566777887777664        233  3333322 21    112223


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +.+++.                  ..++|++|+...+.........+ ..++|+|..+...+        +..+.+..++
T Consensus        63 ~~~~~~------------------~~~~d~ii~~~~~~~~~~~~~~~-~~~ipvv~~~~~~~--------~~~~~v~~d~  115 (303)
T 3KKE_B           63 LSRLVS------------------EGRVDGVLLQRREDFDDDMLAAV-LEGVPAVTINSRVP--------GRVGSVILDD  115 (303)
T ss_dssp             HHHHHH------------------TTSCSCEEECCCTTCCHHHHHHH-HTTSCEEEESCCCT--------TSCCEEEECH
T ss_pred             HHHHHH------------------cCCCCEEEEeccccCCHHHHHHH-HhCCCEEEeCCCCC--------CCCCEEEeCc
Confidence            333322                  14688888654433222333444 67999998776432        1355677777


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE------  271 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~------  271 (908)
                      ...++.+++++.+.+.++++++..+.  .....+.++|++.+++. ++.+.....+..+.+..+..+.++++++      
T Consensus       116 ~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~  194 (303)
T 3KKE_B          116 QKGGGIATEHLITLGHSRIAFISGTAIHDTAQRRKEGYLETLASA-GLRSEAAWVVDAGWEADAGSAALNTLYRGANLGK  194 (303)
T ss_dssp             HHHHHHHHHHHHHTTCCSEEEEESCTTCHHHHHHHHHHHHHHHHT-TCCCCGGGEEECCSSHHHHHHHHHHHHHHHCTTS
T ss_pred             hHHHHHHHHHHHHcCCCcEEEEeCCCCChHHHHHHHHHHHHHHHc-CCCCCceeEEecCCChHHHHHHHHHHHhhcCCCC
Confidence            77888888888777888999998543  35566778888888765 3332211111100111223344444432      


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ..++++|++.. +..+..+++++++.|+.
T Consensus       195 ~~~~~~i~~~~-~~~a~~~~~a~~~~g~~  222 (303)
T 3KKE_B          195 PDGPTAVVVAS-VNAAVGALSTALRLGLR  222 (303)
T ss_dssp             TTSCSEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CCCCCEEEECC-HHHHHHHHHHHHHCCCC
Confidence            13577777664 44566778888877763


No 260
>3BBL_A Regulatory protein of LacI family; Protein Structure Initiative II, PSI-II; HET: EDO; 2.35A {Chloroflexus aggregans}
Probab=96.86  E-value=2.6e-06  Score=84.93  Aligned_cols=146  Identities=13%  Similarity=0.134  Sum_probs=85.5  Template_Neff=11.700

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++|++|+...... ......+...++|+|..+...+       .+..+.+.+++...++.+++++.+.+.++++++..+
T Consensus        63 ~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~~~~~~~~~l~~~g~~~i~~i~~~  134 (287)
T 3BBL_A           63 GNVDGFVLSSINYN-DPRVQFLLKQKFPFVAFGRSNP-------DWDFAWVDIDGTAGTRQAVEYLIGRGHRRIAILAWP  134 (287)
T ss_dssp             TCCSEEEECSCCTT-CHHHHHHHHTTCCEEEESCCST-------TCCCCEEEECHHHHHHHHHHHHHHHTCCCEEEEECC
T ss_pred             CCCCEEEEecCCCC-CHHHHHHHhCCCCEEEeCCCCC-------CCCCcEEEeChHHHHHHHHHHHHHCCCCcEEEEeCC
Confidence            47888887544332 2344556678999998775432       123556667777777788888866678899998844


Q NP_000836.2     225 G--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET---PNARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       225 ~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~---~~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      .  .....+.+++.+.+++. ++.+..........+..+....++++++.   .++|+|++.. +..+..+++++++.|+
T Consensus       135 ~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~i~~~~-~~~~~~~~~~l~~~g~  212 (287)
T 3BBL_A          135 EDSRVGNDRLQGYLEAMQTA-QLPIETGYILRGEGTFEVGRAMTLHLLDLSPERRPTAIMTLN-DTMAIGAMAAARERGL  212 (287)
T ss_dssp             TTCHHHHHHHHHHHHHHHHT-TCCCCGGGEEECCSSHHHHHHHHHHHHTSCTTTSCSEEEESS-HHHHHHHHHHHHHTTC
T ss_pred             ccchHHHHHHHHHHHHHHHC-CCCCCCcceeccCCCHHHHHHHHHHHHccCCCCCCCEEEECC-HHHHHHHHHHHHHCCC
Confidence            2  24556677788777764 33322111111001111233334444321   2467777664 4456778888888776


Q NP_000836.2     300 S  300 (908)
Q Consensus       300 ~  300 (908)
                      .
T Consensus       213 ~  213 (287)
T 3BBL_A          213 T  213 (287)
T ss_dssp             C
T ss_pred             C
Confidence            4


No 261
>4PZ0_A sugar ABC transporter, sugar-binding protein; structural genomics, The Center for; HET: PAV, EDO; 1.25A {Bacillus anthracis}
Probab=96.85  E-value=2.8e-06  Score=86.62  Aligned_cols=213  Identities=13%  Similarity=0.078  Sum_probs=116.2  Template_Neff=11.400

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILD-TCSRDTYALEQSLTF  119 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d-~~~~~~~a~~~~~~~  119 (908)
                      ...+.++||++.|..+.            .++..+..+++.++++.        |++  +.+.+ +..++    ....+.
T Consensus         6 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~--~~~~~~~~~~~----~~~~~~   59 (324)
T 4PZ0_A            6 KKADDVKFAFIPKLTGV------------GFFTSGGEGAKEMGDKL--------GVQ--VKYDGPSEASV----SGQVKY   59 (324)
T ss_dssp             SCGGGCEEEEECSSSSS------------HHHHHHHHHHHHHHHHH--------TCE--EEECCCSSCCH----HHHHHH
T ss_pred             hccCCcEEEEEeCCCCC------------hHHHHHHHHHHHHHHHH--------CCE--EEEECCCCCCH----HHHHHH
Confidence            45678999999986542            25567778888887764        233  33344 22232    223334


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++|+...+.. .......+...++|+|..+...+.      ....+.+..+
T Consensus        60 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~~  114 (324)
T 4PZ0_A           60 INNFIN-------------------QNYDALMVSSTSVDGLSQSLQRAKKKGMTVLTWDSDVNP------KDRSFYISQG  114 (324)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSCSSTTHHHHHHHHHTTCEEEEESSCCCG------GGCSEEEESC
T ss_pred             HHHHHh-------------------cCCCEEEECCCCHHHHHHHHHHHHHCCCEEEEECCCCCc------ccCcEEEecC
Confidence            444332                   47888776543332 224455677789999987764431      1122333344


Q NP_000836.2     199 D-SYQAQAMVDIVTAL-G-WNYVSTLAS--EGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       199 ~-~~~~~~~~~~l~~~-~-~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      + ...++.+++++.+. + .++++++..  ++.+...+.+++++.+++.+ ++++.......  .+..+....+++++..
T Consensus       115 ~~~~~g~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~  192 (324)
T 4PZ0_A          115 TPDQLANLLIEMTSKQIGDKGKVAFFYSSPTVTDQNQWVTKAKEIIKEKYPNWEIVTTQYGE--NNAQKSLSVGENILKT  192 (324)
T ss_dssp             CHHHHHHHHHHHHHHHHTTCEEEEEEESCSSCHHHHHHHHHHHHHHHHHCTTEEEEEEEECT--TCHHHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHHHCCCeeEEEEEcCCCCHHHHHHHHHHHHHHHHHCCCcEEeeeccCC--CCHHHHHHHHHHHHHH
Confidence            3 45566777777543 4 678988874  33455667777887776521 13332211111  1112334445555421


Q NP_000836.2     273 -PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIG  307 (908)
Q Consensus       273 -~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~  307 (908)
                       .++++|++. ++..+..+++++++.|+..++.+++
T Consensus       193 ~~~~~~i~~~-~~~~a~~~~~al~~~g~~~~i~v~g  227 (324)
T 4PZ0_A          193 YPDINAVICP-DATALPAMAQAAENLKMDKKVVVTG  227 (324)
T ss_dssp             CTTCCEEEEC-STTHHHHHHHHHHHTTCBTTBEEEE
T ss_pred             CCCCCEEEec-CCcchHHHHHHHHHCCCCCCeEEEE
Confidence             246666655 3445667778888777632333443


No 262
>4YS6_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; ABC TRANSPORTER, SOLUTE-BINDING PROTEIN, ENZYME; HET: BGC, MSE; 1.698A {Clostridium phytofermentans (strain ATCC 700394 / DSM 18823 / ISDg)}
Probab=96.85  E-value=2.8e-06  Score=88.09  Aligned_cols=217  Identities=9%  Similarity=0.018  Sum_probs=115.7  Template_Neff=11.100

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+.++||++.|..+.            .++.....+++.++++.|          +++.+.|...+.    +...+.
T Consensus        31 ~~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~l~~~~~~~~~----~~~~~~   84 (360)
T 4YS6_A           31 SGKGSDKLVGVAMPTKDL------------QRWNQDGSNMEKQLKDAG----------YEVDLQYASNDV----QTQVSQ   84 (360)
T ss_dssp             ------CEEEEEESCSSS------------THHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHH
T ss_pred             CCCCCCcEEEEEecCCCC------------HHHHhhHHHHHHHHHHcC----------CEEEEEeCCCCH----HHHHHH
Confidence            456678999999987542            245567778887777653          344445544332    222333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAA-SSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~-s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   .+++++|.... +.........+...++|+|..+...+.     ..++.+++.++
T Consensus        85 i~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~d  140 (360)
T 4YS6_A           85 IENMIS-------------------NGCKLLVIASIEGDSLGTVLAQAKKKGISVIAYDRLIMN-----SDAVSYYATFD  140 (360)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSSTTSCHHHHHHHHHTTCEEEEESSCCCS-----CTTCCEEEEEC
T ss_pred             HHHHHH-------------------CCCCEEEEeCCCcccHHHHHHHHHHCCCEEEEECCCCCC-----CCcccEEEEeC
Confidence            444332                   46777765432 222234455667789999987654331     12346677777


Q NP_000836.2     199 DSYQAQAMVDIVTAL-------GWNYVSTLAS--EGNYGESGVEAFTQISREIGG--VCIAQS------QKIPREPRPGE  261 (908)
Q Consensus       199 ~~~~~~~~~~~l~~~-------~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~--i~v~~~------~~~~~~~~~~~  261 (908)
                      +...++.+++++.+.       +.++++++..  ++.++..+.+++++.+++.++  +.+...      .......+..+
T Consensus       141 ~~~~~~~~~~~l~~~~~~~~~~g~~~v~~i~~~~~~~~~~~r~~~~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~  220 (360)
T 4YS6_A          141 NYMVGTKQGEYIKEKLNLETAKGPFNLEIFTGDPGDNNARFFYGGAMDVLKPYVDGGVLVVKSGSVAFEKVATAGWSTET  220 (360)
T ss_dssp             HHHHHHHHHHHHHHHTTTTTCCCCEEEEEEBCCTTCHHHHHHHHHHHHHHHHHHHTTSEECTTCCCSHHHHBCGGGCHHH
T ss_pred             hHHHHHHHHHHHHHHhccccCCCCceEEEEEcCCCChhHHHHHhHHHHHhHhhcCCCeEEEecCceeeeeeccCCCCHHH
Confidence            777777777777543       6779999985  345566777888887766421  221100      00000011111


Q NP_000836.2     262 FEKIIKRLLET-----PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIG  307 (908)
Q Consensus       262 ~~~~~~~l~~~-----~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~  307 (908)
                      ....+++++.+     .++|+|++.. +..+..+++++++.|+..++.+++
T Consensus       221 ~~~~~~~~l~~~~~~~~~~d~i~~~~-~~~a~~~~~al~~~g~~~~i~v~~  270 (360)
T 4YS6_A          221 AQNRMDAIIASYYADGTKLDAVLCSN-DSTALGVTNALTASYKGEWPIVTG  270 (360)
T ss_dssp             HHHHHHHHHHHHSSSSCCCCEEEESS-HHHHHHHHHHHHHHCCSSCCEECC
T ss_pred             HHHHHHHHHHHhhccCCCceEEEECC-hHHHHHHHHHHHHcCCCCCCEEEE
Confidence            11223333211     3567776654 445667788888777632333443


No 263
>3L49_C ABC sugar (Ribose) transporter, periplasmic; SUGAR BINDING/TRANSPORTER, STRUCTURAL GENOMICS, PSI; HET: UNL; 2.3A {Rhodobacter sphaeroides}
Probab=96.84  E-value=2.9e-06  Score=84.69  Aligned_cols=203  Identities=12%  Similarity=0.091  Sum_probs=110.6  Template_Neff=11.900

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ++.++||++.|....            ........+++.++++.|          +++.+.|+..++.    ...+.+++
T Consensus         3 ~~~~~Ig~~~~~~~~------------~~~~~~~~~~~~~~~~~~----------~~~~~~~~~~~~~----~~~~~~~~   56 (291)
T 3L49_C            3 LEGKTIGITAIGTDH------------DWDLKAYQAQIAEIERLG----------GTAIALDAGRNDQ----TQVSQIQT   56 (291)
T ss_dssp             CTTCEEEEEESCCCS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECCSCHH----HHHHHHHH
T ss_pred             CCCcEEEEEecCCCC------------HHHHHHHHHHHHHHHHCC----------CEEEEEeCCCCHH----HHHHHHHH
Confidence            467899999985432            234456667776666543          3444555443322    22233443


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAA-ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++.                   ++++++|+.. .+.........+...++|+|..+...+        ..++++.+++..
T Consensus        57 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~--------~~~~~v~~~~~~  109 (291)
T 3L49_C           57 LIA-------------------QKPDAIIEQLGNLDVLNPWLQKINDAGIPLFTVDTATP--------HAINNTTSNNYS  109 (291)
T ss_dssp             HHH-------------------TCCSEEEEECCCHHHHHHHHHHHHHTTCCEEEESCCCT--------TCSEEEECCHHH
T ss_pred             HHH-------------------cCCCEEEEcCCChhhhHHHHHHHHHCCCCEEEeCCCCC--------CccceeccChHH
Confidence            332                   4788888653 333323445556778999998775432        134555555555


Q NP_000836.2     202 QAQAM-VDIVTALGWN-YVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIP-REPRPGEFEKIIKRLLET-P--  273 (908)
Q Consensus       202 ~~~~~-~~~l~~~~~~-~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~-~~~~~~~~~~~~~~l~~~-~--  273 (908)
                      .+..+ ..++.+.+.+ +++++..  ++.++..+.+++++.+++.+++++....... ...+..+....++++++. .  
T Consensus       110 ~~~~~~~~~~~~~g~~~~v~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  189 (291)
T 3L49_C          110 IGAELALQMVADLGGKGNVLVFNGFYSVPVCKIRYDQMKYVLEAFPDVKIIEPELRDVIPNTIQSAYSNVTDMLTKYPNE  189 (291)
T ss_dssp             HHHHHHHHHHHHTTTCEEEEEECTTTTSHHHHHHHHHHHHHHTTCTTEEECSSCBCCCSSSHHHHHHHHHHHHHHHCCST
T ss_pred             HHHHHHHHHHHHhCCCceEEEEEcCCCCHHHHHHHHHHHHHHHHCCCcEEeccccccCCCCCHHHHHHHHHHHHHHCCCC
Confidence            55433 3444555666 7888875  3445666777887777653223332211000 001112334445555431 1  


Q NP_000836.2     274 -NARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       274 -~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                       ++++|++.. +..+..+++++++.|+
T Consensus       190 ~~~dai~~~~-~~~a~~~~~~l~~~g~  215 (291)
T 3L49_C          190 GDVGAIWACW-DVPMIGATQALQAAGR  215 (291)
T ss_dssp             TSCCEEEESS-SHHHHHHHHHHHHHTC
T ss_pred             CCccEEEEcC-CHHHHHHHHHHHHCCC
Confidence             567777664 4456677888887776


No 264
>3JY6_A Transcriptional regulator, LacI family; NYSGXRC, PSI-II, transcriptional regulator, Lac; 1.97A {Lactobacillus brevis}
Probab=96.83  E-value=3e-06  Score=83.95  Aligned_cols=199  Identities=11%  Similarity=0.090  Sum_probs=113.6  Template_Neff=11.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++..+||++.|..+.            .++.....+++.++++.+        +  ++.+.+...+.    ....+.++
T Consensus         4 ~~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~~   57 (276)
T 3JY6_A            4 TQSSKLIAVIVANIDD------------YFSTELFKGISSILESRG--------Y--IGVLFDANADI----EREKTLLR   57 (276)
T ss_dssp             -CCCCEEEEEESCTTS------------HHHHHHHHHHHHHHHTTT--------C--EEEEEECTTCH----HHHHHHHH
T ss_pred             cCCccEEEEEEcCCCC------------hHHHHHHHHHHHHHHHcC--------C--EEEEEeCCCCH----HHHHHHHH
Confidence            4567899999986532            245567778887776643        2  23344443332    12223333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      .+..                   .++|++|+...+..  .....+...++|+|..+...+       .+..+.+..++..
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~--~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  109 (276)
T 3JY6_A           58 AIGS-------------------RGFDGLILQSFSNP--QTVQEILHQQMPVVSVDREMD-------ACPWPQVVTDNFE  109 (276)
T ss_dssp             HHHT-------------------TTCSEEEEESSCCH--HHHHHHHTTSSCEEEESCCCT-------TCSSCEEECCHHH
T ss_pred             HHHH-------------------cCCCEEEEecCCCc--HHHHHHHhCCCCEEEeCCCCC-------CCCCCeEEeChHH
Confidence            3332                   47888887544332  233445678999988765432       1245566677777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNY---GESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~---~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      .++.+++++.+.+.++++++.....+   ...+.+++.+.+++. ++.......+    +..+....+++++. ..++++
T Consensus       110 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~----~~~~~~~~~~~~l~~~~~~~~  184 (276)
T 3JY6_A          110 AAKAATTAFRQQGYQHVVVLTSELELSRTRQERYRGILAAAQDV-DVLEVSESSY----NHSEVHQRLTQLITQNDQKTV  184 (276)
T ss_dssp             HHHHHHHHHHTTTCCEEEEEEECSTTCHHHHHHHHHHHTTCSEE-EEEEECSSSC----CHHHHHHHHHHHHHSSSSCEE
T ss_pred             HHHHHHHHHHHCCCCEEEEEcCccccchhHHHHHHHHHHHHHhC-CCeEeeccCC----CHHHHHHHHHHHHhcCCCCcE
Confidence            77788888766678899998854332   455667777776654 3322111111    11223344555542 135677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       185 i~~~~-~~~a~~~~~~l~~~g~~  206 (276)
T 3JY6_A          185 AFALK-ERWLLEFFPNLIISGLI  206 (276)
T ss_dssp             EEESS-HHHHHHHSHHHHHSSSC
T ss_pred             EEEcC-hHHHHHHHHHHHHcCCC
Confidence            76653 44566677777777763


No 265
>3JY6_D Transcriptional regulator, LacI family; NYSGXRC, PSI-II, transcriptional regulator, Lac; 1.97A {Lactobacillus brevis}
Probab=96.83  E-value=3e-06  Score=83.95  Aligned_cols=199  Identities=11%  Similarity=0.090  Sum_probs=111.5  Template_Neff=11.700

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++..+||++.|..+.            .++.....+++.++++.+        +  ++.+.+...+.    ....+.++
T Consensus         4 ~~~~~~Ig~~~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~~   57 (276)
T 3JY6_D            4 TQSSKLIAVIVANIDD------------YFSTELFKGISSILESRG--------Y--IGVLFDANADI----EREKTLLR   57 (276)
T ss_dssp             ----CEEEEEESCTTS------------HHHHHHHHHHHHHHHTTT--------C--EEEEEECTTCH----HHHHHHHH
T ss_pred             cCCccEEEEEEcCCCC------------hHHHHHHHHHHHHHHHcC--------C--EEEEEeCCCCH----HHHHHHHH
Confidence            4567899999986532            245567778887776643        2  23344443332    12223333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      .+..                   .++|++|+...+..  .....+...++|+|..+...+       .+..+.+..++..
T Consensus        58 ~l~~-------------------~~~d~ii~~~~~~~--~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  109 (276)
T 3JY6_D           58 AIGS-------------------RGFDGLILQSFSNP--QTVQEILHQQMPVVSVDREMD-------ACPWPQVVTDNFE  109 (276)
T ss_dssp             HHHH-------------------TTCSEEEECSSCCH--HHHHHHSCSCCCEEEESSCCS-------SCSSCEEEECHHH
T ss_pred             HHHH-------------------cCCCEEEEecCCCc--HHHHHHHhCCCCEEEeCCCCC-------CCCCCeEEeChHH
Confidence            3332                   47888887544332  233445678999988765432       1245566677777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGNY---GESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~~---~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      .++.+++++.+.+.++++++.....+   ...+.+++.+.+++. ++.......+    +..+....+++++. ..++++
T Consensus       110 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~----~~~~~~~~~~~~l~~~~~~~~  184 (276)
T 3JY6_D          110 AAKAATTAFRQQGYQHVVVLTSELELSRTRQERYRGILAAAQDV-DVLEVSESSY----NHSEVHQRLTQLITQNDQKTV  184 (276)
T ss_dssp             HHHHHHHHHHTTTCCEEEEEEECGGGCHHHHHHHHHHHTTCSEE-EEEEECTTCC-----CHHHHHHHHHHHHSSCCCEE
T ss_pred             HHHHHHHHHHHCCCCEEEEEcCccccchhHHHHHHHHHHHHHhC-CCeEeeccCC----CHHHHHHHHHHHHhcCCCCcE
Confidence            77788888766678899998854332   455667777776654 3322111111    11223344555542 135677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       185 i~~~~-~~~a~~~~~~l~~~g~~  206 (276)
T 3JY6_D          185 AFALK-ERWLLEFFPNLIISGLI  206 (276)
T ss_dssp             EEESS-HHHHHHHSHHHHHSSCC
T ss_pred             EEEcC-hHHHHHHHHHHHHcCCC
Confidence            76653 44566677777777763


No 266
>5HQJ_A Periplasmic binding protein/LacI transcriptional regulator; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: 64K, MSE; 1.55A {Burkholderia graminis C4D1M}
Probab=96.83  E-value=3e-06  Score=85.67  Aligned_cols=204  Identities=10%  Similarity=0.095  Sum_probs=114.8  Template_Neff=11.700

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+.++||++.+.+.             .++..+..+++.++++.+        +++.+...++ .++    +...+.
T Consensus        23 ~~~~~~~~Ig~~~~~~~-------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~-~~~----~~~~~~   76 (311)
T 5HQJ_A           23 MKDAKDISVAVIPKVAV-------------PFFDDCNKGAKTAADKAG--------VKYQWVVPQN-TQG----STQVQI   76 (311)
T ss_dssp             CCCGGGCEEEEECSSSC-------------TTHHHHHHHHHHHHHHHT--------CEEEECCCSS-SSS----HHHHHH
T ss_pred             cccCCCceEEEecCCCC-------------HHHHHHHHHHHHHHHHHC--------CEEEEECCCC-CCH----HHHHHH
Confidence            34567899999665432             245677888888888763        3444433332 221    122333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVI-GAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   ++++++| ++..+.........+...++|+|..+...+.      .++.+++.++
T Consensus        77 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d  131 (311)
T 5HQJ_A           77 IEDLIS-------------------RHVDGIAISVNEPKSVESVMKRAEQSGIKVLTYDSDSPK------SGRSMYIGTN  131 (311)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSSTGGGHHHHHHHHTTTCEEEEESSCCTT------SCCSCEEECC
T ss_pred             HHHHHH-------------------cCCCEEEEcCCCHHHHHHHHHHHHHcCCeEEEEcCCCCC------CCCcEEEecC
Confidence            444332                   4678775 4443333233445566789999987764321      2456677777


Q NP_000836.2     199 DSYQAQAMVDIVTA--LGWNYVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TP  273 (908)
Q Consensus       199 ~~~~~~~~~~~l~~--~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~  273 (908)
                      ....++.+++++.+  .+.++++++..  +..+...+.+++++.+++..++++.......  .+..+....+++++. ..
T Consensus       132 ~~~~~~~~~~~l~~~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~  209 (311)
T 5HQJ_A          132 NEQAGATMAETMGKALNGQGEVAIITGQLGAVNLNERIAGIKKGLAKYPGIKVVETQGTD--DDLARGVSVVETTLRAHP  209 (311)
T ss_dssp             HHHHHHHHHHHHHHHTTTEEEEEEECSCTTCHHHHHHHHHHHHHHTTCTEEEEEEEECCT--TCHHHHHHHHHHHHHHCT
T ss_pred             HHHHHHHHHHHHHHHcCCCeeEEEEECCCCCccHHHHHHHHHHHHHhCCCcEEEEecCCC--ccHHHHHHHHHHHHHHCC
Confidence            77778888888765  57789999985  3445666777888877653124443221111  111223344444442 12


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKL  297 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~  297 (908)
                      ++++|++.. +..+..+++++++.
T Consensus       210 ~~~~i~~~~-~~~a~~~~~~~~~~  232 (311)
T 5HQJ_A          210 NLKGIFGVS-QVGGPAVAKVLNTR  232 (311)
T ss_dssp             TEEEEEECS-TTHHHHHHHHHTST
T ss_pred             CccEEEEec-CCcHHHHHHHHHHH
Confidence            567776654 33445566666543


No 267
>3EJW_A SmLsrB; Periplasmic binding protein, Plasmid, SIGNALING; HET: PAV; 1.8A {Sinorhizobium meliloti}
Probab=96.81  E-value=3.3e-06  Score=85.59  Aligned_cols=211  Identities=10%  Similarity=-0.016  Sum_probs=114.6  Template_Neff=11.400

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++..+..+++.++++.+        +++.+...+ ..++    +...+.+++++
T Consensus         1 ~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~~-~~~~----~~~~~~~~~l~   55 (315)
T 3EJW_A            1 ENQIAFIPKLVGV------------GFFTSGGAGAVKAGEEVG--------AKVTYDGPT-EPSV----SGQVQFINNFV   55 (315)
T ss_dssp             CCEEEEECSCSSS------------HHHHHHHHHHHHHHHHHT--------CEEEECCCS-SCCH----HHHHHHHHHHH
T ss_pred             CcEEEEEeccCCC------------hHHHHHHHHHHHHHHHHC--------CEEEEECCC-CCCH----HHHHHHHHHHH
Confidence            3689999987652            255677888888888763        334333221 2222    22333444443


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP-PDSYQ  202 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~-~~~~~  202 (908)
                      .                   ++++++|+...+.. .......+...++|+|..+...+.      ....+.+.. +....
T Consensus        56 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~~~~~~~  110 (315)
T 3EJW_A           56 N-------------------QGYNALIVSSVSPDGLCPALKRAMERGVLVMTWDSDVNP------DCRSYYINQGTPEQL  110 (315)
T ss_dssp             H-------------------TTCSEEEECCSCSSTTHHHHHHHHHTTCEEEEESSCCCG------GGCSEEEESCCHHHH
T ss_pred             H-------------------cCCCEEEEcCCChhhhHHHHHHHHHCCCEEEEEcCCCCc------ccccEEEeCCCHHHH
Confidence            2                   47888776543322 224455667789999987764431      111222333 45555


Q NP_000836.2     203 AQAMVDIVTAL--G-WNYVSTLAS--EGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNA  275 (908)
Q Consensus       203 ~~~~~~~l~~~--~-~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~  275 (908)
                      ++.+++++.+.  + .++++++..  ++.++..+.++|++.+++.+ ++++.......  .+..+....++++++ ..++
T Consensus       111 g~~~~~~l~~~~~~~~~~i~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~  188 (315)
T 3EJW_A          111 GGLLVDMAAEGVKKEKAKVAFFYSSPTVTDQNAWAEAAKAKIAKEHPGWEIVTTQYGY--NDAQKSLQTAESILQTYPDL  188 (315)
T ss_dssp             HHHHHHHHHHHHCCSSEEEEEEESCSSCHHHHHHHHHHHHHHHHHCTTEEEEEEEECT--TCHHHHHHHHHHHHHHCTTC
T ss_pred             HHHHHHHHHHHcccCCCcEEEEEcCCCcHHHHHHHHHHHHHHHHHCCCcEEeecccCC--CCHHHHHHHHHHHHHHCCCC
Confidence            66777776443  3 688998875  34456667778888776531 23332211111  111233344555542 1256


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++|+... +..+..+++++++.|+..++.+++.
T Consensus       189 ~~i~~~~-~~~a~~~~~al~~~g~~~~v~v~~~  220 (315)
T 3EJW_A          189 DAIIAPD-ANALPAAAQAAENLKRAEGVTIVGF  220 (315)
T ss_dssp             CEEEECS-TTHHHHHHHHHHHHTCTTTCEEEEB
T ss_pred             CEEEeCC-CCchHHHHHHHHHcccCCCCEEEEe
Confidence            6666553 4456677888888776323444443


No 268
>3QK7_C Transcriptional regulators; STRUCTURAL GENOMICS, NEW YORK STRUCTURAL; 2.7A {Yersinia pestis}
Probab=96.81  E-value=3.3e-06  Score=84.46  Aligned_cols=207  Identities=11%  Similarity=0.100  Sum_probs=115.7  Template_Neff=11.800

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .+++.+||++.|.++...        ...+...+..+++.++++.+        +++  .+.+.. +.    +...+.++
T Consensus         3 ~~~~~~I~~i~~~~~~~~--------~~~~~~~~~~~~~~~~~~~g--------~~~--~~~~~~-~~----~~~~~~~~   59 (294)
T 3QK7_C            3 LGRTDAIALAYPSRPRVL--------NNSTFLEMISWIGIELGKRG--------LDL--LLIPDE-PG----EKYQSLIH   59 (294)
T ss_dssp             --CCCEEEEEEESSSGGG--------CCHHHHHHHHHHHHHHHTTT--------CEE--EEEEEC-TT----CCCHHHHH
T ss_pred             CCCCCeEEEEecCCchhh--------cCHHHHHHHHHHHHHHHHcC--------CeE--EEEeCC-Ch----hHHHHHHH
Confidence            356789999998643100        01244566677777666542        333  333322 21    12223333


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      ++..                   .++|++|....+... .....+...++|+|..+...+       .+.++.+.++...
T Consensus        60 ~~~~-------------------~~~d~ii~~~~~~~~-~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  112 (294)
T 3QK7_C           60 LVET-------------------RRVDALIVAHTQPED-FRLQYLQKQNFPFLALGRSHL-------PKPYAWFDFDNHA  112 (294)
T ss_dssp             HHHT-------------------TCCSEEEECSCCSSC-HHHHHHHHTTCCEEEESCCCC-------SSCCEEEEECHHH
T ss_pred             HHHh-------------------CCCCEEEEeCCCCCc-HHHHHHHHCCCCEEEECCCCC-------CCCCeEEEeChHH
Confidence            3322                   478888865444333 344556668999998775432       1345667777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .++.+++++.+.+.++++++..+.  .....+.+++++.+++. ++.+..........+..+....++++++ ..++|+|
T Consensus       113 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d~i  191 (294)
T 3QK7_C          113 GASLAVKRLLELGHQRIAFVSTDARISYVDQRLQGYVQTMSEA-GLMPLAGYLQKADPTRPGGYLAASRLLALEVPPTAI  191 (294)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEEECSCSHHHHHHHHHHHHHHHHT-TCCCCTTCEEEECSSHHHHHHHHHHHHTSSSCCSEE
T ss_pred             HHHHHHHHHHHCCCCeEEEEeCCCCCcHHHHHHHHHHHHHHHC-CCCCcccceecCCCCchHHHHHHHHHHcCCCCCCEE
Confidence            788888888767888999988532  34556777888887765 3433211111100111223344555542 1357777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       192 ~~~~-~~~a~~~~~~l~~~g~~  212 (294)
T 3QK7_C          192 ITDC-NMLGDGVASALDKAGLL  212 (294)
T ss_dssp             EESS-HHHHHHHHHHHHHHTCB
T ss_pred             EECC-cHHHHHHHHHHHHcCCC
Confidence            7654 44566778888877763


No 269
>3E3M_D Transcriptional regulator, LacI family; STRUCTURAL GENOMICS, TRANSCRIPTION, DNA-binding, Plasmid; 1.6A {Silicibacter pomeroyi}
Probab=96.81  E-value=3.3e-06  Score=87.29  Aligned_cols=204  Identities=13%  Similarity=0.136  Sum_probs=115.2  Template_Neff=11.300

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++..+||+++|..+.            .++.....+++.++++.+        +  ++.+.+...++    +...+.++
T Consensus        67 ~~~~~~I~~v~~~~~~------------~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~~  120 (355)
T 3E3M_D           67 TKRSGFVGLLLPSLNN------------LHFAQTAQSLTDVLEQGG--------L--QLLLGYTAYSP----EREEQLVE  120 (355)
T ss_dssp             ----CEEEEEESCSBC------------HHHHHHHHHHHHHHHHTT--------C--EEEEEECTTCH----HHHHHHHH
T ss_pred             cCCCCEEEEEecCCCC------------hhHHHHHHHHHHHHHHCC--------C--EEEEEeCCCCh----HHHHHHHH
Confidence            3567899999986532            245566777777665542        2  33344443332    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+.... ........+.+.++|+|..+...+       .+..+++..++..
T Consensus       121 ~~~~-------------------~~~d~ii~~~~~-~~~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  173 (355)
T 3E3M_D          121 TMLR-------------------RRPEAMVLSYDG-HTEQTIRLLQRASIPIVEIWEKPA-------HPIGHTVGFSNER  173 (355)
T ss_dssp             HHHH-------------------TCCSEEEEECSC-CCHHHHHHHHTSCSCEEEESSCCS-------SCSSEEEECCHHH
T ss_pred             HHHH-------------------hCCCEEEEcCCC-CCHHHHHHHHHCCCCEEEEcCCCC-------CCCCcEEEeCHHH
Confidence            3332                   478888874322 233445566678999998875432       1345566777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN---YGESGVEAFTQISREIGGVCIAQSQKIP-REPRPGEFEKIIKRLLE-TPNAR  276 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~-~~~~~~~~~~~~~~l~~-~~~~~  276 (908)
                      .+..+++++.+.+.++|+++.....   ....+.++|++.+++. ++.+....... ...+..+....+++++. ..++|
T Consensus       174 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~r~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~d  252 (355)
T 3E3M_D          174 AAYDMTNALLARGFRKIVFLGEKDDDWTRGAARRAGFKRAMREA-GLNPDQEIRLGAPPLSIEDGVAAAELILQEYPDTD  252 (355)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEEESSCTTSHHHHHHHHHHHHHHHT-TSCSCCEEEESCSSCCHHHHHHHHHHHHHHCTTCC
T ss_pred             HHHHHHHHHHHCCCCeEEEEcCCCCCchhHHHHHHHHHHHHHHC-CCCCCcceecCCCCCCHHHHHHHHHHHHHHCCCCc
Confidence            7778888876667889999875432   2456777888887765 34322111100 00111223344555442 13578


Q NP_000836.2     277 AVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       277 viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +|++.. +..+..+++++++.|+.
T Consensus       253 ai~~~~-~~~a~~~~~al~~~g~~  275 (355)
T 3E3M_D          253 CIFCVS-DMPAFGLLSRLKSIGVA  275 (355)
T ss_dssp             EEEESS-HHHHHHHHHHHHHHTCC
T ss_pred             EEEECC-cHHHHHHHHHHHHcCCC
Confidence            787764 44566788888888763


No 270
>2WRZ_A L-ARABINOSE-BINDING PERIPLASMIC PROTEIN; SUGAR TRANSPORT, ARABINOSE BINDING PROTEIN; 2.2A {ESCHERICHIA COLI}
Probab=96.80  E-value=3.5e-06  Score=84.89  Aligned_cols=206  Identities=12%  Similarity=0.097  Sum_probs=109.7  Template_Neff=11.900

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      +++||++.|..+.            .++..+..+++.++++.|          +++.+.+. .+.    +...+.+++++
T Consensus         2 ~~~I~~i~~~~~~------------~~~~~~~~~~~~~~~~~~----------~~l~~~~~-~~~----~~~~~~~~~l~   54 (306)
T 2WRZ_A            2 NLKLGFLVAQPEE------------PASQTQWKFADKAGKDLG----------FEVIKIAV-PDG----EKTLNAIDSLA   54 (306)
T ss_dssp             CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHHT----------CEEEEEEC-SSH----HHHHHHHHHHH
T ss_pred             CeEEEEEeCCCCC------------hHHHHHHHHHHHHHHHhC----------CEEEEEeC-CCH----HHHHHHHHHHH
Confidence            5789999987542            245667788888887753          23333343 221    22333444433


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGV-IGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQA  203 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~v-Ig~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~  203 (908)
                      .                   .+++++ +++..+.........+...++|+|..+...+.... ...++++++.+++...+
T Consensus        55 ~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~-~~~~~~~~v~~d~~~~~  114 (306)
T 2WRZ_A           55 A-------------------SGAKGFVISTPDPKLGSAIVAKARGYDMKVIAVDNQFVNAKG-KPMDTVPLVMEAATKIG  114 (306)
T ss_dssp             H-------------------HTCCEEEEECSCGGGHHHHHHHHHHTTCEEEEESSCCBCTTS-CBCCSSCEEECCHHHHH
T ss_pred             H-------------------CCCCEEEEeCCCcchhHHHHHHHHhCCCEEEEEcCcccCCCC-CCcccccEEecchHHHH
Confidence            2                   467774 44444433334455566789999988764432110 01234666777776667


Q NP_000836.2     204 QAMVDIVTA----LGWN--YVSTLAS---EGNYGESGVEAFTQISREIG--GVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       204 ~~~~~~l~~----~~~~--~v~ii~~---~~~~~~~~~~~~~~~~~~~~--~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      +.+++++.+    .+++  ++.++..   +..++..+.+++++.+++.+  ...+.......  .+..+....++++++ 
T Consensus       115 ~~~~~~l~~~~~~~g~~~~~i~v~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~~--~~~~~~~~~~~~~l~-  191 (306)
T 2WRZ_A          115 ERQGQELYKEMQKRGWDVKESAVMAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKS--EDIPGAFDAANSMLV-  191 (306)
T ss_dssp             HHHHHHHHHHHHHHTCCGGGEEEEEEECTTSHHHHHHHHHHHHHHHHTTCCGGGEEEEECSS--SSHHHHHHHHHHHHH-
T ss_pred             HHHHHHHHHHHHHcCCCccceEEEEEEcCCChhhHHHHHHHHHHHHHcCCCCceeEEecCCC--CChhHHHHHHHHHHH-
Confidence            777766533    4555  6665542   22345567778888777642  01221111100  111233445555543 


Q NP_000836.2     273 PNARA---VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       273 ~~~~v---iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      .+++.   ++++.++..+..+++++++.|+.
T Consensus       192 ~~~~~~~~~i~~~~~~~a~~~~~~l~~~g~~  222 (306)
T 2WRZ_A          192 QHPEVKHWLIVGMNDSTVLGGVRATEGQGFK  222 (306)
T ss_dssp             TCTTCSEEEEECSSHHHHHHHHHHHHHTTCC
T ss_pred             hCCCCceEEEEecChHHHHHHHHHHHhCCCC
Confidence            23332   23333344566788888887764


No 271
>5BQ3_A Rhamnose ABC transporter, rhamnose-binding protein; ABC transporter, Structural Genomics, Joint; HET: MSE; 2.6A {Actinomyces odontolyticus ATCC 17982}
Probab=96.78  E-value=3.7e-06  Score=85.92  Aligned_cols=218  Identities=11%  Similarity=0.032  Sum_probs=115.3  Template_Neff=11.600

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNI-TLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~-~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      .....+.++||++.|..+.            .++.....+++.++++.+        + ++.+.. ++..++    ....
T Consensus        21 ~~~~~~~~~Igv~~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~~~~~-~~~~~~----~~~~   75 (332)
T 5BQ3_A           21 GSYDVSSQSITFIPKQLNN------------PFSDVMLGGGKNAAGEIG--------FAEVNVVG-PLEASS----SSQV   75 (332)
T ss_dssp             CCCCCSSCEEEEECSSSSC------------HHHHHHHHHHHHHHHHHT--------CSEEEECC-CSSCCT----TTTH
T ss_pred             CcccCCCcEEEEEeCCCCC------------HHHHHHHHHHHHHHHHhC--------CcEEEEEC-CCCCCH----HHHH
Confidence            4556778999999986542            245667778888887753        3 344433 332222    2223


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVI-GAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vI-g~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +.+++++.                   ++++++| ++..+.........+...++|+|..+...+.     .....+...
T Consensus        76 ~~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~v~~  131 (332)
T 5BQ3_A           76 SFINSEVQ-------------------AGTNVLVIAANDPDAVCPALQDARKAGTKVVTFDSDSAA-----DCRDLFINQ  131 (332)
T ss_dssp             HHHHHHHH-------------------TTCSEEEECCSSTTTSHHHHHHHHHHTCEEEEESSCCCT-----TSCSEEEES
T ss_pred             HHHHHHHH-------------------hCCCEEEEeCCCHHhhHHHHHHHHHcCCEEEEECCCCCc-----cccceeEec
Confidence            33444332                   4678744 4443333334445566789999987765431     011222222


Q NP_000836.2     197 PPDSYQAQAMVDIVTAL--GWNYVSTLAS--EGNYGESGVEAFTQISRE---IGGVCIAQSQKIPREPRPGEFEKIIKRL  269 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~~--~~~~v~ii~~--~~~~~~~~~~~~~~~~~~---~~~i~v~~~~~~~~~~~~~~~~~~~~~l  269 (908)
                      .+....++.+++++.+.  +.++++++..  +..+...+.+.+++.+++   ..++++.......  .+..+....++++
T Consensus       132 ~~~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~  209 (332)
T 5BQ3_A          132 VESKQVAITMLDMVSDQIGGSGKVAILSATANAANQNAWIKFMEDEIASNDKYKGIEIVAKVYGD--DDDTKSFQEAQGL  209 (332)
T ss_dssp             SCHHHHHHHHHHHHHHHHTSCEEEEEEESCTTCHHHHHHHHHHHHHHHHCTTSTTEEEEEEEECT--TCHHHHHHHHHHH
T ss_pred             cCHHHHHHHHHHHHHHHhCCCeEEEEEECCCCCHHHHHHHHHHHHHHHhchhcCCeEEEEEEeCC--CCHHHHHHHHHHH
Confidence            44555566777776554  5678999985  333455666777766642   1123332111111  1112233445555


Q NP_000836.2     270 LET-PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       270 ~~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++. .+.++|+... +..+..+++++++.|+..++.+++.
T Consensus       210 l~~~~~~~~i~~~~-~~~a~~~~~~l~~~g~~~~v~vi~~  248 (332)
T 5BQ3_A          210 LQAHPDLNAIVSPT-TVGIAATARYLSTSDYKGKVFLTGL  248 (332)
T ss_dssp             HHHCTTCCEEEECS-HHHHHHHHHHHHHSTTTTTSEEEEB
T ss_pred             HHHCCCcCEEEeCC-cchHHHHHHHHhhcCCCCcEEEEEe
Confidence            421 2455665543 4445567778877776323444443


No 272
>4RY0_A Probable ribose ABC transporter, substrate-binding; SUGAR TRANSPORTER, ENZYME FUNCTION INITIATIVE; HET: RIP; 1.4A {Rhizobium etli CFN 42}
Probab=96.77  E-value=3.9e-06  Score=83.60  Aligned_cols=211  Identities=9%  Similarity=0.047  Sum_probs=113.7  Template_Neff=12.000

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      +..+||++.|..+.            .++.....+++.++++.+          +++.+.++..++.    ...+.++++
T Consensus         2 ~~~~I~~v~~~~~~------------~~~~~~~~~~~~~~~~~g----------~~~~~~~~~~~~~----~~~~~~~~l   55 (289)
T 4RY0_A            2 MADLIAIITPAHDN------------PFFKAEAVGAEAKAKELG----------YETLVMTHDDDAN----KQSEMIDTA   55 (289)
T ss_dssp             CCCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCHH----HHHHHHHHH
T ss_pred             ccceEEEEecCCCC------------HHHHHHHHHHHHHHHHhC----------CEEEEEcCCCCHH----HHHHHHHHH
Confidence            46789999987542            255667778887777642          3344444433321    222333333


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAA-ASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~-~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      +.                   ++++++|... ...........+.+.++|+|..+...+.     ..++++++.+++...
T Consensus        56 ~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~d~~~~  111 (289)
T 4RY0_A           56 IG-------------------RGAKAIILDNAGADASVAAVKKAKDAGIPSFLIDREINA-----TGVAVAQIVSNNYQG  111 (289)
T ss_dssp             HH-------------------TTCSEEEECCSCTTTHHHHHHHHHHTTCCEEEESSCCSC-----SSSSSEEEEECHHHH
T ss_pred             Hh-------------------cCCCEEEEeCCChhhhHHHHHHHHHCCCCEEEeCCCCCC-----CCCceEEEEcCcHHH
Confidence            32                   4677665433 2222223345566789999987654331     123456677777777


Q NP_000836.2     203 AQAMVDIVTALGWN--YVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       203 ~~~~~~~l~~~~~~--~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      ++.+++++.+.+.+  +++++..  +..+...+.++|++.+++.+...+.......  .+..+....+++++. ..++|+
T Consensus       112 ~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~~~d~  189 (289)
T 4RY0_A          112 AQLGAQEFVKLMGEKGNYVELVGKESDTNAGIRSQGYHDVIDDYPEMKSVAKQSAN--WSQTEAYSKMETILQANPDIKG  189 (289)
T ss_dssp             HHHHHHHHHHHHTTCEEEEEEECCTTSHHHHHHHHHHHHHHTTCTTEEEEEEEECT--TCHHHHHHHHHHHHHHCTTCCE
T ss_pred             HHHHHHHHHHHhCCCccEEEEEcCCCChhHHHHHHHHHHHHHHCCCeEEEEeeeCC--CCHHHHHHHHHHHHHHCCCCCE
Confidence            77888877654433  3555543  2334556777888877664212221111000  111223344555542 135777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      |++.. +..+..+++++++.|.. ++.+++.
T Consensus       190 i~~~~-~~~a~~~~~a~~~~~~~-~~~ii~~  218 (289)
T 4RY0_A          190 VISGN-DTMAMGAIAALQAAGRK-DVIVVGF  218 (289)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCT-TSEEECS
T ss_pred             EEECC-hHHHHHHHHHHHHCCCC-CeEEEEe
Confidence            76664 44566777888777662 3344443


No 273
>3TB6_A Arabinose metabolism transcriptional repressor; transcription regulation, arabinose binding, DNA; HET: ARB, GOL; 2.21A {Bacillus subtilis}
Probab=96.75  E-value=4.4e-06  Score=83.69  Aligned_cols=206  Identities=12%  Similarity=0.113  Sum_probs=114.5  Template_Neff=12.000

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...+..+||++.|..+.            .++..+..+++.++++.|          +++.+.+...++    +...+.+
T Consensus        11 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~~----------~~~~~~~~~~~~----~~~~~~~   64 (298)
T 3TB6_A           11 ALHSNKTIGVLTTYISD------------YIFPSIIRGIESYLSEQG----------YSMLLTSTNNNP----DNERRGL   64 (298)
T ss_dssp             ----CCEEEEEESCSSS------------TTHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHH
T ss_pred             hccCCCeEEEEecCCcc------------hhHHHHHHHHHHHHHHcC----------CcEEEEecCCCH----HHHHHHH
Confidence            45568899999997542            256677888888887753          233444443332    2223334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSI----MVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~----~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      ++++.                   ++++++|+...+....    .....+...++|+|..+...+       .+..+++.
T Consensus        65 ~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~~~~ip~v~~~~~~~-------~~~~~~v~  118 (298)
T 3TB6_A           65 ENLLS-------------------QHIDGLIVEPTKSALQTPNIGYYLNLEKNGIPFAMINASYA-------ELAAPSFT  118 (298)
T ss_dssp             HHHHH-------------------TCCSEEEECCSSTTSCCTTHHHHHHHHHTTCCEEEESSCCT-------TCSSCEEE
T ss_pred             HHHHh-------------------CCCCEEEEecCCcccCCCChHHHHHHHHcCCCEEEEecCCC-------CCCCCEEE
Confidence            44332                   4788888654433211    222355678999998776443       13456667


Q NP_000836.2     197 PPDSYQAQAMVDIVTALGWNYVSTLAS-EGNYGESGVEAFTQISREIGGVCIAQS--QKIPREPRPGEFEKIIKRLLE--  271 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~~~~~~v~ii~~-~~~~~~~~~~~~~~~~~~~~~i~v~~~--~~~~~~~~~~~~~~~~~~l~~--  271 (908)
                      .+....++.+++++.+.+.++++++.. ++..+..+.++|++.+++. ++.....  .......+..+..+.++++++  
T Consensus       119 ~d~~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~  197 (298)
T 3TB6_A          119 LDDVKGGMMAAEHLLSLGHTHMMGIFKADDTQGVKRMNGFIQAHRER-ELFPSPDMIVTFTTEEKESKLLEKVKATLEKN  197 (298)
T ss_dssp             ECHHHHHHHHHHHHHHTTCCSEEEEEESSSHHHHHHHHHHHHHHHHT-TCCCCGGGEEEECHHHHTTHHHHHHHHHHHHT
T ss_pred             eCHHHHHHHHHHHHHHCCCCeEEEEEcCCCccchHHHHHHHHHHHhC-CCCCChhhEEEecchHHHHHHHHHHHHHHHHc
Confidence            777777778888876667888888874 3345566777888877764 2322111  001100111111222333321  


Q NP_000836.2     272 -TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 -~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                       ..++++|++.. +..+..+++++++.|+.
T Consensus       198 ~~~~~~~i~~~~-~~~a~~~~~~l~~~g~~  226 (298)
T 3TB6_A          198 SKHMPTAILCYN-DEIALKVIDMLREMDLK  226 (298)
T ss_dssp             TTSCCSEEECSS-HHHHHHHHHHHHHTTCC
T ss_pred             ccCCCCEEEEcC-hHHHHHHHHHHHHCCCC
Confidence             12478887764 44566778888877763


No 274
>3GYB_A Transcriptional regulators (LACI-FAMILY TRANSCRIPTIONAL REGULATORY; Transcription, Protein Structure Initiative II(PSI; 1.6A {Corynebacterium glutamicum}
Probab=96.70  E-value=5.4e-06  Score=82.18  Aligned_cols=198  Identities=14%  Similarity=0.080  Sum_probs=111.6  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||++.|..+.            .++..+..+++.++++.        |+++  .+.+...+ .    ...+.+++
T Consensus         3 ~~~~~I~~v~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~~--~~~~~~~~-~----~~~~~~~~   55 (280)
T 3GYB_A            3 LRTQLIAVLIDDYSN------------PWFIDLIQSLSDVLTPK--------GYRL--SVIDSLTS-Q----AGTDPITS   55 (280)
T ss_dssp             -CCCEEEEEESCTTS------------GGGHHHHHHHHHHHGGG--------TCEE--EEECSSSS-C----SSSCHHHH
T ss_pred             CCCcEEEEEecCCCC------------hHHHHHHHHHHHHHHHh--------CcEE--EEEecCCC-c----ccchHHHH
Confidence            457899999987542            25566777888777664        2333  33333222 1    12223333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   +++|++|+.......     .+...++|++..+...+.      .+..+.+.+++...
T Consensus        56 ~~~-------------------~~~d~ii~~~~~~~~-----~~~~~~~pvv~~~~~~~~------~~~~~~v~~d~~~~  105 (280)
T 3GYB_A           56 ALS-------------------MRPDGIIIAQDIPDF-----TVPDSLPPFVIAGTRITQ------ASTHDSVANDDFRG  105 (280)
T ss_dssp             HHT-------------------TCCSEEEEESCC-------------CCCEEEESCCCSS------SCSTTEEEECHHHH
T ss_pred             HHh-------------------cCCCEEEEeCCCCCC-----CCcccCCCEEEeCCCCCC------CCCCcEEEeChHHH
Confidence            332                   478888875433321     134568998876653321      13456677777777


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAVIMF  281 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~viv~~  281 (908)
                      ++.+++++.+.+.++++++..+......+.++|.+.+++. ++.+....... ..+..+....+++++.. .++++|++.
T Consensus       106 ~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~-~~~~~~~~~~~~~~l~~~~~~~~i~~~  183 (280)
T 3GYB_A          106 AEIATKHLIDLGHTHIAHLRVGSGAGLRRFESFEATMRAH-GLEPLSNDYLG-PAVEHAGYTETLALLKEHPEVTAIFSS  183 (280)
T ss_dssp             HHHHHHHHHHTTCCSEEEECCSSHHHHHHHHHHHHHHHHT-TCCCEECCCCS-CCCHHHHHHHHHHHHHHCTTCCEEEES
T ss_pred             HHHHHHHHHHCCCCeEEEEeCCCcchHHHHHHHHHHHHHC-CCCCCcccccC-CcccchHHHHHHHHHHhCCCCCEEEEC
Confidence            8888888876677899998865556667778888887765 34433221111 01112233444455421 246777766


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~  300 (908)
                      . +..+..+++++++.|+.
T Consensus       184 ~-~~~a~~~~~~~~~~g~~  201 (280)
T 3GYB_A          184 N-DITAIGALGAARELGLR  201 (280)
T ss_dssp             S-HHHHHHHHHHHHHHTCC
T ss_pred             C-HHHHHHHHHHHHHcCCC
Confidence            4 34566778888877764


No 275
>3GYB_B Transcriptional regulators (LACI-FAMILY TRANSCRIPTIONAL REGULATORY; Transcription, Protein Structure Initiative II(PSI; HET: MSE; 1.6A {Corynebacterium glutamicum}
Probab=96.70  E-value=5.4e-06  Score=82.18  Aligned_cols=198  Identities=14%  Similarity=0.080  Sum_probs=106.1  Template_Neff=11.800

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      +++++||++.|..+.            .++..+..+++.++++.        |+++  .+.+...+ .    ...+.+++
T Consensus         3 ~~~~~I~~v~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~~--~~~~~~~~-~----~~~~~~~~   55 (280)
T 3GYB_B            3 LRTQLIAVLIDDYSN------------PWFIDLIQSLSDVLTPK--------GYRL--SVIDSLTS-Q----AGTDPITS   55 (280)
T ss_dssp             --CCEEEEEESCTTS------------GGGHHHHHHHHHHHGGG--------TCEE--EEECSSSS-C----SSSCHHHH
T ss_pred             CCCcEEEEEecCCCC------------hHHHHHHHHHHHHHHHh--------CcEE--EEEecCCC-c----ccchHHHH
Confidence            457899999987542            25566777888777664        2333  33333222 1    12223333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   +++|++|+.......     .+...++|++..+...+.      .+..+.+.+++...
T Consensus        56 ~~~-------------------~~~d~ii~~~~~~~~-----~~~~~~~pvv~~~~~~~~------~~~~~~v~~d~~~~  105 (280)
T 3GYB_B           56 ALS-------------------MRPDGIIIAQDIPDF-----TVPDSLPPFVIAGTRITQ------ASTHDSVANDDFRG  105 (280)
T ss_dssp             HHT-------------------TCCSEEEEECSSSSS-----CCCBCCC---------------------CCCEECHHHH
T ss_pred             HHh-------------------cCCCEEEEeCCCCCC-----CCcccCCCEEEeCCCCCC------CCCCcEEEeChHHH
Confidence            332                   478888875433321     134568998876653321      13456677777777


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAVIMF  281 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~viv~~  281 (908)
                      ++.+++++.+.+.++++++..+......+.++|.+.+++. ++.+....... ..+..+....+++++.. .++++|++.
T Consensus       106 ~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~~-~~~~~~~~~~~~~~l~~~~~~~~i~~~  183 (280)
T 3GYB_B          106 AEIATKHLIDLGHTHIAHLRVGSGAGLRRFESFEATMRAH-GLEPLSNDYLG-PAVEHAGYTETLALLKEHPEVTAIFSS  183 (280)
T ss_dssp             HHHHHHHHHHTTCCSEEEECCSSHHHHHHHHHHHHHHHHT-TCCCEECCCCS-CCCHHHHHHHHHHHHHHCTTCCEEEES
T ss_pred             HHHHHHHHHHCCCCeEEEEeCCCcchHHHHHHHHHHHHHC-CCCCCcccccC-CcccchHHHHHHHHHHhCCCCCEEEEC
Confidence            8888888876677899998865556667778888887765 34433221111 01112233444455421 246777766


Q NP_000836.2     282 ANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       282 ~~~~~~~~~l~~~~~~g~~  300 (908)
                      . +..+..+++++++.|+.
T Consensus       184 ~-~~~a~~~~~~~~~~g~~  201 (280)
T 3GYB_B          184 N-DITAIGALGAARELGLR  201 (280)
T ss_dssp             S-HHHHHHHHHHHHHHTCC
T ss_pred             C-HHHHHHHHHHHHHcCCC
Confidence            4 34566778888877764


No 276
>5UFH_A LacI-type transcriptional regulator; Human Microbiome, structural genomics, PSI-Biology; HET: NO3, MSE; 1.45A {Bifidobacterium animalis subsp. lactis (strain AD011)}
Probab=96.67  E-value=5.9e-06  Score=85.04  Aligned_cols=202  Identities=10%  Similarity=0.039  Sum_probs=112.8  Template_Neff=11.300

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ....+||++.|..+.            .++..+..+++.++++.+        +.+.  +.+...++    ....+.++.
T Consensus        63 ~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~--~~~~~~~~----~~~~~~~~~  116 (347)
T 5UFH_A           63 GTTGLLGLAIFDFSQ------------PFASYLADQIIVCAREHH--------YGVI--INTYGQNE----HGLARAMRQ  116 (347)
T ss_dssp             ---CEEEEEESCSSS------------HHHHHHHHHHHHHHHHTT--------CEEE--EEECTTST----THHHHHHHH
T ss_pred             CCCCeEEEEEcCCCC------------hhHHHHHHHHHHHHHHCC--------CEEE--EEcCCCCh----HHHHHHHHH
Confidence            467889999986432            245567777777776642        2333  33332221    122233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   .++|++|+......  .....+...++|+|..+...+       ......+..++...
T Consensus       117 ~~~-------------------~~~d~ii~~~~~~~--~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~~  168 (347)
T 5UFH_A          117 ANN-------------------LAADGWIVFADHAM--GQHSKMLDQSYPLVLTGDWDA-------YGKVDQVTMPNVEA  168 (347)
T ss_dssp             GGG-------------------SSCSEEEEECCSCC--CC--CTTCCSSCEEEESSSCC-------TTSSEEEECCHHHH
T ss_pred             HHh-------------------cCCCEEEEEccccc--chhHHHHhcCCCEEEeCCccc-------CCCCcEEEcCHHHH
Confidence            332                   47888876544322  223445567999997765432       13455666777777


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEGN------------YGESGVEAFTQISREIGGVCIAQSQKIPRE-PRPGEFEKIIKRL  269 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~~------------~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~-~~~~~~~~~~~~l  269 (908)
                      ++.+++++.+.+.++++++..+..            +...+.++|++.+++. ++.+.....+... .+..+....++++
T Consensus       169 ~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~  247 (347)
T 5UFH_A          169 MRYTTNRLLDSGYRSIALFGADGSLGARHYRQATEGTQELRVQGYMQAYEEH-GIEARMDMLFSGGLLTSDSGVRATNLM  247 (347)
T ss_dssp             HHHHHHHHHHTTCCCEEEESSCGGGCHHHHHHCCSCHHHHHHHHHHHHHHHT-TCCCCGGGEECCSSSSHHHHHHHHHHH
T ss_pred             HHHHHHHHHHcCCCeEEEEcCCcccchhhhhccCcccHHHHHHHHHHHHHHC-CCCCCHHHeecCCCCChHHHHHHHHHH
Confidence            888888886678889999985432            4456778888888775 3443221111100 1111223344444


Q NP_000836.2     270 LE-TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       270 ~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +. ..++|+|++.. +..+..+++++++.|+.
T Consensus       248 ~~~~~~~~ai~~~~-d~~a~~~~~~l~~~g~~  278 (347)
T 5UFH_A          248 MDQGVRPDAIICLN-DAMALGALHQLQVRGIR  278 (347)
T ss_dssp             HHTTCCCSEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             HHcCCCCCEEEECC-HHHHHHHHHHHHHCCCC
Confidence            32 13678887764 44567778888887764


No 277
>3CTP_A Periplasmic binding protein/LacI transcriptional regulator; STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE; HET: XLF; 1.41A {Alkaliphilus metalliredigens}
Probab=96.67  E-value=6e-06  Score=84.26  Aligned_cols=198  Identities=13%  Similarity=0.148  Sum_probs=114.7  Template_Neff=11.500

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+..+||++.|..+.            .++..+..+++.++++.+          +++.+.+...+.    ....+.++
T Consensus        57 ~~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  110 (330)
T 3CTP_A           57 TKNSKTIGLMVPNISN------------PFFNQMASVIEEYAKNKG----------YTLFLCNTDDDK----EKEKTYLE  110 (330)
T ss_dssp             ---CCEEEEEESCTTS------------HHHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHHH
T ss_pred             cCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHCC----------CEEEEEeCCCCH----HHHHHHHH
Confidence            3567899999986432            245567777777776642          234444543332    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+..     ..+...++|+|..+...+        +..+++..++..
T Consensus       111 ~~~~-------------------~~~d~ii~~~~~~~-----~~~~~~~ipvv~~~~~~~--------~~~~~v~~d~~~  158 (330)
T 3CTP_A          111 VLQS-------------------HRVAGIIASRSQCE-----DEYANIDIPVVAFENHIL--------DNIITISSDNYN  158 (330)
T ss_dssp             HHHH-------------------TTCSEEEEETCCCS-----GGGTTCCSCEEEESSCCC--------TTSCEEEECHHH
T ss_pred             HHHH-------------------CCCCEEEEeCCCCh-----HHHhcCCCCEEEEcCCCc--------cCCcEEEcCcHH
Confidence            3332                   47888886543322     235667999998765432        245667777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVI  279 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv  279 (908)
                      .+..+++++.+.++++++++..+.  .+...+.+++++.+++. ++.+.... ...+.+..+....++.+....++|+|+
T Consensus       159 ~g~~~~~~l~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~i~  236 (330)
T 3CTP_A          159 GGRMAFDHLYEKGCRKILHIKGPEVFEATELRYKGFLDGARAK-DLEIDFIE-FQHDFQVKMLEEDINSMKDIVNYDGIF  236 (330)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEECCTTCHHHHHHHHHHHHHHHHT-TCCCEEEE-CSSSCCGGGGGCCCTTGGGGGGSSEEE
T ss_pred             HHHHHHHHHHHcCCCcEEEEeCCccchhHHHHHHHHHHHHHHC-CCCCCeEE-ecccccHHHHHHHHHHhhhcCCCCEEE
Confidence            788888888777888999988543  35566778888887764 34432211 110011122333444443223578777


Q NP_000836.2     280 MFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       280 ~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +.. +..+..+++++++.|+.
T Consensus       237 ~~~-~~~a~~~~~al~~~g~~  256 (330)
T 3CTP_A          237 VFN-DIAAATVMRALKKRGVS  256 (330)
T ss_dssp             ESS-HHHHHHHHHHHHHTTCC
T ss_pred             EcC-HHHHHHHHHHHHHCCCC
Confidence            764 44566778888887763


No 278
>3G85_A Transcriptional regulator (LacI family); Transcription regulator, PSI-II, 11230o, Structural; 1.84A {Clostridium acetobutylicum ATCC 824}
Probab=96.67  E-value=6e-06  Score=82.30  Aligned_cols=204  Identities=12%  Similarity=0.083  Sum_probs=115.0  Template_Neff=11.700

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ..++..+||++.|....           ..++.....+++.++++.+        +.+++.+.+...+...    ...  
T Consensus         7 ~~~~~~~I~~i~~~~~~-----------~~~~~~~~~g~~~a~~~~g--------~~~~~~~~~~~~~~~~----~~~--   61 (289)
T 3G85_A            7 NSQSKPTIALYWSSDIS-----------VNIISRFLRGLQSKLAKQN--------YNYNVVICPYKTDCLH----LEK--   61 (289)
T ss_dssp             ----CCEEEEEEETTSC-----------GGGHHHHHHHHHHHHHHTT--------TCSEEEEEEECTTCGG----GCG--
T ss_pred             cCCCCCeEEEEeCCCCC-----------cHHHHHHHHHHHHHHHHcC--------CCcEEEEEEcCCChHH----Hhh--
Confidence            45578999999983211           1356677888888887752        2345555554433211    111  


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      +.+..                   .++|++|+...+......... ...++|+|..+...         +.+..+..++.
T Consensus        62 ~~~~~-------------------~~~d~ii~~~~~~~~~~~~~~-~~~~ipvv~~~~~~---------~~~~~v~~d~~  112 (289)
T 3G85_A           62 GISKE-------------------NSFDAAIIANISNYDLEYLNK-ASLTLPIILFNRLS---------NKYSSVNVDNY  112 (289)
T ss_dssp             GGSTT-------------------TCCSEEEESSCCHHHHHHHHH-CCCSSCEEEESCCC---------SSSEEEEECHH
T ss_pred             chhhh-------------------cCCCEEEEecCCcccHHHHHH-hCCCCCEEEeCCCc---------cCCCEEEeCcH
Confidence            01111                   578888865443322223333 46789999877532         23456667777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      ..++.+++++.+.+.++++++..+.  .....+.++|++.+++. ++.+..........+..+..+.+++++. ..++++
T Consensus       113 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~l~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~  191 (289)
T 3G85_A          113 KMGEKASLLFAKKRYKSAAAILTESLNDAMDNRNKGFIETCHKN-GIKISENHIIAAENSIHGGVDAAKKLMKLKNTPKA  191 (289)
T ss_dssp             HHHHHHHHHHHHTTCCBCEEEECCCSSHHHHHHHHHHHHHHHHT-TCBCCGGGEEECCSSHHHHHHHHHHHTTSSSCCSE
T ss_pred             HHHHHHHHHHHHcCCCeeEEEecCCCChHHHHHHHHHHHHHHHc-CCCCCccceEEcCCChHHHHHHHHHHHhcCCCCCE
Confidence            7788888888777888998887432  34566778888888765 3443321111100111223344455432 135777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       192 i~~~~-~~~a~~~~~~l~~~g~~  213 (289)
T 3G85_A          192 LFCNS-DSIALGVISVLNKRQIS  213 (289)
T ss_dssp             EEESS-HHHHHHHHHHHHHTTCC
T ss_pred             EEECC-HHHHHHHHHHHHHCCCC
Confidence            77664 44566778888877764


No 279
>3H5O_B Transcriptional regulator GntR; 11234b, transcription regulator, GntR, Chromobacterium; HET: MSE, SO4; 2.3A {Chromobacterium violaceum}
Probab=96.67  E-value=6.1e-06  Score=84.58  Aligned_cols=203  Identities=14%  Similarity=0.107  Sum_probs=113.6  Template_Neff=11.300

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+..+||++.|..+.            .++.....+++.++++.+          +++.+.|+..++    +...+.++
T Consensus        59 ~~~~~~I~~v~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~~  112 (339)
T 3H5O_B           59 SAKSRTVLVLIPSLAN------------TVFLETLTGIETVLDAAG----------YQMLIGNSHYDA----GQELQLLR  112 (339)
T ss_dssp             ----CEEEEEESCSTT------------CTTHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHHH
T ss_pred             cCCCCEEEEEEcCCCC------------hhHHHHHHHHHHHHHHcC----------CeEEEEeCCCCh----hHHHHHHH
Confidence            3567899999986542            245567778877776643          233444543332    22233344


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                   .++|++|+...+.. ......+...++|+|..+...+        +.++.+..++..
T Consensus       113 ~l~~-------------------~~~d~ii~~~~~~~-~~~~~~~~~~~ipvv~~~~~~~--------~~~~~v~~d~~~  164 (339)
T 3H5O_B          113 AYLQ-------------------HRPDGVLITGLSHA-EPFERILSQHALPVVYMMDLAD--------DGRCCVGFSQED  164 (339)
T ss_dssp             HHHT-------------------TCCSEEEEESSCCC-TTHHHHHHHTTCCEEEEESCCS--------SSCCEEECCHHH
T ss_pred             HHHh-------------------cCCCEEEEeCCCCC-hHHHHHHHhCCCCEEEEccCCC--------CCCcEEEcCHHH
Confidence            4332                   46888886543332 3344556678999998764321        345566677777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASE-GNYGESGVEAFTQISREIGGVCIAQSQKIPR-EPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~-~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .++.+++++.+.+.++++++... +.....+.++|++.+++. +..+........ ..+.......+++++. ..++|+|
T Consensus       165 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~r~~~~~~~l~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~d~I  243 (339)
T 3H5O_B          165 AGAAITRHLLSRGKRRIGFLGAQLDERVMKRLDGYRAALDAA-DCRDAGLEWLDPQPSSMQMGADMLDRALAERPDCDAL  243 (339)
T ss_dssp             HHHHHHHHHHHTTCCSEEEEEESCCHHHHHHHHHHHHHHHHH-TCCCGGGEEEECSCCCHHHHHHHHHHHHHHCTTCCEE
T ss_pred             HHHHHHHHHHHCCCCcEEEEeCCCCHHHHHHHHHHHHHHHHC-CCcccCCccccCCCCCHHHHHHHHHHHHHhCCCCCEE
Confidence            78888888876688899999854 334556777888877764 232211111110 0011112233333332 1356777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       244 ~~~~-~~~a~~~~~~l~~~g~~  264 (339)
T 3H5O_B          244 FCCN-DDLAIGALARSQQLGIA  264 (339)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHcCCC
Confidence            7664 44566778888877763


No 280
>5YSZ_A Transcriptional regulator, LacI family; transcriptional regulator, cellulase gene regulator; HET: CBI, GOL; 1.631A {Thermobifida fusca YX}
Probab=96.62  E-value=7.5e-06  Score=84.75  Aligned_cols=148  Identities=11%  Similarity=0.080  Sum_probs=89.0  Template_Neff=11.100

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++|++|+...+... .....+...++|+|..+...+.     ..+.++.+..++...+..+++++.+.+.++++++..+
T Consensus       143 ~~~d~ii~~~~~~~~-~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~d~~~~~~~~~~~l~~~g~~~i~~l~~~  216 (360)
T 5YSZ_A          143 QHVDGVLLLSLHRDD-PLPQMLDEAGVPYVYGGRPLGV-----PEEQVSYVDIDNIGGGRQATQRLIETGHRRIATIAGP  216 (360)
T ss_dssp             SCCSEEEEESCCTTC-SHHHHHHHHTCCEEEESCCTTS-----CGGGCCEEEECHHHHHHHHHHHHHHTTCSSEEEEECC
T ss_pred             CCCCEEEEECCCCCC-chHHHHHHcCCCEEEeCCCCCC-----CcccCcEEEcCcHHHHHHHHHHHHHcCCCcEEEEeCC
Confidence            578888765433332 3445566789999987754321     1245667777777788888888876788899999854


Q NP_000836.2     225 GN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       225 ~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ..  +...+.++|++.+++. ++.+........+.+..+....++++++ ..++|+|++.. +..+..+++++++.|..
T Consensus       217 ~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~daI~~~~-d~~a~~~~~al~~~g~~  293 (360)
T 5YSZ_A          217 QDMVAGVERLQGYREALLAA-GMEYDETLVSYGDFTYDSGVAAMRELLDRAPDVDAVFAAS-DLMGLAALRVLRASGRR  293 (360)
T ss_dssp             TTSHHHHHHHHHHHHHHHHT-TCCCCGGGEEECCSSHHHHHHHHHHHHHHCTTCCEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             cccHHHHHHHHHHHHHHHHC-CCCCCHhheeecCCCHHHHHHHHHHHHHhCCCCCEEEECC-hHHHHHHHHHHHHcCCC
Confidence            33  5566778888887765 3433211111100112233444555542 12477777664 44566778888877763


No 281
>3MIZ_A Putative transcriptional regulator protein, LacI; Lacl family, Protein Structure Initiative; HET: MSE; 1.91A {Rhizobium etli}
Probab=96.58  E-value=8.6e-06  Score=81.66  Aligned_cols=206  Identities=13%  Similarity=0.104  Sum_probs=115.6  Template_Neff=11.800

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...+..+||++.|.....           .+...+..+++.++++.+          +++.+.+...++    +...+.+
T Consensus         9 ~~~~~~~I~~v~~~~~~~-----------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~~   63 (301)
T 3MIZ_A            9 RSSRSNTFGIITDYVSTT-----------PYSVDIVRGIQDWANANG----------KTILIANTGGSS----EREVEIW   63 (301)
T ss_dssp             ---CCCEEEEEESSTTTC-----------CSCHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHHH
T ss_pred             hcCCCCEEEEEecCCCCC-----------chHHHHHHHHHHHHHHcC----------CeEEEEecCCCH----HHHHHHH
Confidence            456789999999854211           245567778777776642          233444443332    2223334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   +++|++|+.......  ....+...++|+|..+...+.      .+.++.+..++.
T Consensus        64 ~~~~~-------------------~~~d~ii~~~~~~~~--~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~d~~  116 (301)
T 3MIZ_A           64 KMFQS-------------------HRIDGVLYVTMYRRI--VDPESGDVSIPTVMINCRPQT------RELLPSIEPDDY  116 (301)
T ss_dssp             HHHHH-------------------TTCSEEEEEEEEEEE--CCCCCTTCCCCEEEEEEECSS------TTSSCEEEECHH
T ss_pred             HHHHh-------------------CCCCEEEEecCCccc--CCcccccCCCCEEEEcCCCCC------cccCCcceeChH
Confidence            43332                   478888865433221  222456789999987764321      234567777777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPR-----EPRPGEFEKIIKRLLET-  272 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~-----~~~~~~~~~~~~~l~~~-  272 (908)
                      ..++.+++++.+.+.++++++..+.  .....+.+++++.+++. ++.+.....+..     ..+..+....++++++. 
T Consensus       117 ~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~  195 (301)
T 3MIZ_A          117 QGARDLTRYLLERGHRRIGYIRLNPILLGAELRLDAFRRTTSEF-GLTENDLSISLGMDGPVGAENNYVFAAATEMLKQD  195 (301)
T ss_dssp             HHHHHHHHHHHTTTCCSEEEEECCTTSHHHHHHHHHHHHHHHHH-TCCGGGEEEEECEESSTTSCEECHHHHHHHHHTST
T ss_pred             HHHHHHHHHHHHCCCCcEEEEecCcccccHHHHHHHHHHHHHHc-CCChhhceEEecCCCCCCcccchHHHHHHHHHhcC
Confidence            7888888888666788999988533  23456777888887765 344321111100     00111122344554421 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      .++++|++.. +..+..+++++++.|+.
T Consensus       196 ~~~~~i~~~~-~~~a~~~~~~l~~~g~~  222 (301)
T 3MIZ_A          196 DRPTAIMSGN-DEMAIQIYIAAMALGLR  222 (301)
T ss_dssp             TCCSEEEESS-HHHHHHHHHHHHTTTCC
T ss_pred             CCCCEEEECC-HHHHHHHHHHHHHCCCC
Confidence            2477777664 44566777777777763


No 282
>1TJY_A sugar transport protein; PROTEIN-LIGAND COMPLEX, SIGNALING PROTEIN; HET: PAV; 1.3A {Salmonella typhimurium} SCOP: c.93.1.1
Probab=96.56  E-value=9.4e-06  Score=82.17  Aligned_cols=210  Identities=10%  Similarity=-0.009  Sum_probs=113.6  Template_Neff=11.200

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDT-CSRDTYALEQSLTFVQA  122 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~-~~~~~~a~~~~~~~~~~  122 (908)
                      ++++||++.|..+.            .++.....+++.++++.+        +++.  +.+. ..+.    ....+.+++
T Consensus         2 ~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~g--------~~~~--~~~~~~~~~----~~~~~~~~~   55 (316)
T 1TJY_A            2 SAERIAFIPKLVGV------------GFFTSGGNGAQEAGKALG--------IDVT--YDGPTEPSV----SGQVQLVNN   55 (316)
T ss_dssp             CCCEEEEECSSSSS------------HHHHHHHHHHHHHHHHHT--------CEEE--ECCCSSCCH----HHHHHHHHH
T ss_pred             CCeEEEEEecCCCC------------HHHHHHHHHHHHHHHHhC--------CEEE--EECCCCCCH----HHHHHHHHH
Confidence            46789999987542            255677788888877752        3333  3333 2222    223334444


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAAS-SVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP-PDS  200 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s-~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~-~~~  200 (908)
                      ++.                   .+++++++...+ .........+...++|+|......+.      .+..+.+.. ++.
T Consensus        56 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~------~~~~~~v~~~d~~  110 (316)
T 1TJY_A           56 FVN-------------------QGYDAIIVSAVSPDGLCPALKRAMQRGVKILTWDSDTKP------ECRSYYINQGTPK  110 (316)
T ss_dssp             HHH-------------------TTCSEEEECCSSSSTTHHHHHHHHHTTCEEEEESSCCCG------GGCSEEEESCCHH
T ss_pred             HHH-------------------cCCCEEEEcCCChhhhHHHHHHHHHCCCEEEEECCCCCc------hhceeEEecCCHH
Confidence            332                   467877764333 22234455667789999987764331      122334444 455


Q NP_000836.2     201 YQAQAMVDIVTAL-G--WNYVSTLAS--EGNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLET-P  273 (908)
Q Consensus       201 ~~~~~~~~~l~~~-~--~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~  273 (908)
                      ..++.+++++.+. +  .++|+++..  ++.....+.++|++.+++.. ++.+.......  .+..+....+++++.. .
T Consensus       111 ~~g~~~~~~l~~~~~~~~~~v~~l~~~~~~~~~~~r~~g~~~~~~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~l~~~~  188 (316)
T 1TJY_A          111 QLGSMLVEMAAHQVDKEKAKVAFFYSSPTVTDQNQWVKEAKAKISQEHPGWEIVTTQFGY--NDATKSLQTAEGIIKAYP  188 (316)
T ss_dssp             HHHHHHHHHHHHHHCSSSEEEEEEESCSSCHHHHHHHHHHHHHHHHHCTTEEEEEEEECT--TCHHHHHHHHHHHHHHCS
T ss_pred             HHHHHHHHHHHHHhCCCCCeEEEEECCCCcHHHHHHHHHHHHHHHHHCCCcEEEeeccCC--CCHHHHHHHHHHHHHHCC
Confidence            6677777777543 5  678998875  33455667778888776531 23333211111  1112233445555421 2


Q NP_000836.2     274 NARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       274 ~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      ++++|+... +..+..+++++++.|+. ++.+++.
T Consensus       189 ~~~~i~~~~-~~~a~~~~~al~~~g~~-~v~v~g~  221 (316)
T 1TJY_A          189 DLDAIIAPD-ANALPAAAQAAENLKRN-NLAIVGF  221 (316)
T ss_dssp             SCCEEEECS-TTHHHHHHHHHHHTTCC-SCEEEEB
T ss_pred             CCCEEEecC-CCchHHHHHHHHHcCCC-CcEEEEe
Confidence            456665543 44556677787777762 3334443


No 283
>4O5A_A LacI family transcription regulator; structural genomics, PSI-Biology, protein structure; HET: SO4, GOL; 1.777A {Bifidobacterium animalis subsp. lactis}
Probab=96.55  E-value=9.7e-06  Score=83.19  Aligned_cols=207  Identities=12%  Similarity=0.108  Sum_probs=115.3  Template_Neff=11.600

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      ..+..+||++.|.++....       ...++..+..+++.++++.+        +  ++.+.+...+.     ...+.+.
T Consensus        65 ~~~~~~Igvv~~~~~~~~~-------~~~~~~~~~~g~~~~~~~~g--------~--~~~~~~~~~~~-----~~~~~~~  122 (345)
T 4O5A_A           65 QSRTRRIGLVLGYDPQLLS-------AEPYIMRLISGLGSALEERD--------Y--SLLVRMSMDDD-----DEVSILE  122 (345)
T ss_dssp             -CCCCEEEEEEECC---------------CHHHHHHHHHHHHGGGT--------C--EEEEEEECSSS-----HHHHHHH
T ss_pred             cCCCCEEEEEEeCChHHhc-------cChHHHHHHHHHHHHHHHCC--------C--EEEEEecCCCc-----cHHHHHH
Confidence            4567899999987531000       01245567777777776542        2  23333332221     1112222


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      +++.                  ..++|++|+...+.....+..+....++|+|..+...+       .+.++++.+++..
T Consensus       123 ~~~~------------------~~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~  177 (345)
T 4O5A_A          123 DWIA------------------TGNVDALLLLNLEIGDPRIELMKNNPQMPCLALADSSL-------TSGLPTLMSDDAA  177 (345)
T ss_dssp             HHHH------------------HTCSSEEEECSCCTTCHHHHHHHTCTTSCEEEEECGGG-------TTTSCEEECCHHH
T ss_pred             HHHH------------------hCCCCEEEEeCCcCCChHHHHHHhCCCCCEEEEccccc-------CCCCCEEEeCcHH
Confidence            2221                  15788888755443332222333357999988765432       1345667777778


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~vi  278 (908)
                      .+..+++++.+.+.++++++.....  ....+.++|.+.+++. ++.+.. ....  .+..+....+++++. ..++|+|
T Consensus       178 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~l~~~-~~~~~~-~~~~--~~~~~~~~~~~~~l~~~~~~dai  253 (345)
T 4O5A_A          178 ASGTMIRHLALFGHKNIARVAGPEELGHSYIRDAAFSEITTEL-GMRYRC-LHTD--YTPESGAEATKRLLSVEPRPTAI  253 (345)
T ss_dssp             HHHHHHHHHHHTTCCEEEEEECCTTSTTHHHHHHHHHHHHHHT-TCEEEE-EECC--SCHHHHHHHHHHHHHSSSCCSEE
T ss_pred             HHHHHHHHHHHcCCCeEEEEeCchhccchHHHHHHHHHHHHHh-CCceEE-EecC--CCHHHHHHHHHHHhcCCCCCCEE
Confidence            8888888887778889999985332  4556778888888765 344321 1111  111223344455432 2367888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|+.
T Consensus       254 ~~~~-d~~a~~~~~~l~~~g~~  274 (345)
T 4O5A_A          254 IYDN-DVMALAGESVASVKGVR  274 (345)
T ss_dssp             EESS-HHHHHHHHHHHHHHTCC
T ss_pred             EECC-HHHHHHHHHHHHHcCCC
Confidence            7764 44566788888887763


No 284
>3UUG_B Multiple sugar-binding periplasmic receptor ChvE; periplasmic binding protein, SUGAR-BINDING PROTEIN; HET: BDP; 1.75A {Agrobacterium tumefaciens}
Probab=96.50  E-value=1.2e-05  Score=81.98  Aligned_cols=206  Identities=10%  Similarity=0.011  Sum_probs=114.2  Template_Neff=11.400

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      +..+||++.|....            .++.....+++.++++.|        +  ++.+.+...+.    +...+.++++
T Consensus         2 ~~~~Ig~v~~~~~~------------~~~~~~~~~~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~~~l   55 (330)
T 3UUG_B            2 DKGSVGIAMPTKSS------------ARWIDDGNNIVKQLQEAG--------Y--KTDLQYADDDI----PNQLSQIENM   55 (330)
T ss_dssp             CCCEEEEEECCSSS------------THHHHHHHHHHHHHHHTT--------C--EEEEEECTTCH----HHHHHHHHHH
T ss_pred             CCceEEEEcCCCCC------------HHHHHHhhHHHHHHHHcC--------C--EEEEEecCCCH----HHHHHHHHHH
Confidence            46789999987521            245567778887777653        2  33344433332    1223333433


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      +.                   .+++++|+...+... ......+...++|+|..+...+.     ..++++++.+++...
T Consensus        56 ~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~~d~~~~  111 (330)
T 3UUG_B           56 VT-------------------KGVKVLVIASIDGTTLSDVLKQAGEQGIKVIAYDRLIRN-----SGDVSYYATFDNFQV  111 (330)
T ss_dssp             HH-------------------HTCSEEEECCSSGGGGHHHHHHHHHTTCEEEEESSCCCS-----CTTCCEEEEECHHHH
T ss_pred             Hh-------------------cCCCEEEEecCCccchHHHHHHHHHCCCEEEEEcCCCCC-----CCCccEEEEeChHHH
Confidence            32                   478887765433322 23445566789999987754331     123456677777777


Q NP_000836.2     203 AQAMVDIVTA-------LGWNYVSTLAS--EGNYGESGVEAFTQISREIGG-VCIAQSQK-------IPREPRPGEFEKI  265 (908)
Q Consensus       203 ~~~~~~~l~~-------~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~-i~v~~~~~-------~~~~~~~~~~~~~  265 (908)
                      +..+++++.+       .+.++++++..  ++..+..+.++|++.+++.+. ..+.....       .....+..+....
T Consensus       112 ~~~~~~~l~~~~~~~~~~g~~~i~~i~~~~~~~~~~~~~~g~~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~  191 (330)
T 3UUG_B          112 GVLQATSITDKLGLKDGKGPFNIELFGGSPDDNNAFFFYDGAMSVLKPYIDSGKLVVKSGQMGMDKVGTLRWDPATAQAR  191 (330)
T ss_dssp             HHHHHHHHHHHHTGGGTCCCEEEEECCCCTTCHHHHHHHHHHHHHHHHHHHHTSEECTTCCCSHHHHCCGGGCHHHHHHH
T ss_pred             HHHHHHHHHHHhcccCCCCCcEEEEEecCCCCccHHHHHHHHHHHhHHhhhcCcEEEeeCCcccccccccCCCHHHHHHH
Confidence            7777777654       46778998873  334556677788877765421 11211100       0000111223344


Q NP_000836.2     266 IKRLLET----PNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       266 ~~~l~~~----~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      +++++..    .++++|++.. +..+..+++++++.|+.
T Consensus       192 ~~~~l~~~~~~~~~~ai~~~~-~~~a~~~~~al~~~g~~  229 (330)
T 3UUG_B          192 MDNLLSAYYTDAKVDAVLSPY-DGLSIGIISSLKGVGYG  229 (330)
T ss_dssp             HHHHHHHHCSSSCCCEEECSS-HHHHHHHHHHHHHTTCS
T ss_pred             HHHHHHhhcCCCCccEEEeCC-cHHHHHHHHHHHhCCCC
Confidence            4555421    2367776664 44566778888877764


No 285
>3LKV_A uncharacterized CONSERVED DOMAIN PROTEIN; ATPase Binding Cassette, PSI, MCSG; HET: PHE; 2.2A {Vibrio cholerae}
Probab=96.46  E-value=1.3e-05  Score=80.10  Aligned_cols=215  Identities=8%  Similarity=0.110  Sum_probs=114.8  Template_Neff=12.100

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      .....++||++.|...             .++.....+++.++++.+..    .|+++++.+.|+..++.    ...+.+
T Consensus         4 ~~~~~~~I~~v~~~~~-------------~~~~~~~~~~~~~~~~~g~~----~g~~~~~~~~~~~~~~~----~~~~~~   62 (302)
T 3LKV_A            4 IMAKTAKVAVSQIVEH-------------PALDATRQGLLDGLKAKGYE----EGKNLEFDYKTAQGNPA----IAVQIA   62 (302)
T ss_pred             ccCCCeEEEEEcCCCC-------------HHHHHHHHHHHHHHHHhCCC----CCceEEEEEEcCCCCHH----HHHHHH
Confidence            4456889999998642             24556667777666654321    24567776666544322    222333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSD-----NTRYDFFSRV  195 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~-----~~~~~~~~~~  195 (908)
                      +++..                   .+++++|+.... ....... . ..++|+|......+....     .....+++.+
T Consensus        63 ~~~~~-------------------~~~d~ii~~~~~-~~~~~~~-~-~~~ipvv~~~~~~~~~~~~~~~~~~~~~~~~~~  120 (302)
T 3LKV_A           63 RQFVG-------------------ENPDVLVGIATP-TAQALVS-A-TKTIPIVFTAVTDPVGAKLVKQLEQPGKNVTGL  120 (302)
T ss_pred             HHHHH-------------------CCCCEEEEeCCc-hHHHHHH-H-hcCCCEEEEcCCCCCccchhhcCCCCCCcEEEc
Confidence            33322                   478888874322 2222222 2 679999987754432110     0012233333


Q NP_000836.2     196 VPPDSYQAQAMVDIVTAL--GWNYVSTLASEGN-YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~--~~~~v~ii~~~~~-~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                        +....++.+++++.+.  +.+++++++.+.. ++..+.+++++.+++. ++.+......    +..+....++++.  
T Consensus       121 --~~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~~----~~~~~~~~~~~~~--  191 (302)
T 3LKV_A          121 --SDLSPVEQHVELIKEILPNVKSIGVVYNPGEANAVSLMELLKLSAAKH-GIKLVEATAL----KSADVQSATQAIA--  191 (302)
T ss_pred             --CHHHHHHHHHHHHHHHCCCCcEEEEEeCCCChhHHHHHHHHHHHHHcC-CCeEeEeeCC----CHHHHHHHHHHHC--
Confidence              3333456667776554  7789999985443 4556677788777664 3544322111    1123444455443  


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIGS  308 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~~  308 (908)
                      .++++|++..+ ..+..+++++.+.+...++.+++.
T Consensus       192 ~~~~~i~~~~~-~~~~~~~~~~~~~~~~~~i~i~~~  226 (302)
T 3LKV_A          192 EKSDVIYALID-NTVASAIEGMIVAANQAKTPVFGA  226 (302)
T ss_pred             CCCCEEEECCc-hHHHHHHHHHHHCCCCCCCcEEEe
Confidence            36788876653 345556666666554323444443


No 286
>4KQC_A Periplasmic binding protein/LacI transcriptional regulator; structural genomics, APC110243, ABC transporter; HET: NO3; 1.62A {Brachyspira murdochii}
Probab=96.39  E-value=1.8e-05  Score=80.11  Aligned_cols=209  Identities=12%  Similarity=0.062  Sum_probs=109.7  Template_Neff=11.600

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      ++..+||++.|....            .++..+..+++.++++.        |+++.+...++..+.    ....+.+++
T Consensus         2 ~~~~~I~~v~~~~~~------------~~~~~~~~~~~~~~~~~--------g~~~~~~~~~~~~~~----~~~~~~i~~   57 (319)
T 4KQC_A            2 NADPYIAVVSKGFQH------------KFWVTVRDGAEAAAKQN--------GVKISFVGPETESDS----KIQQDLLDS   57 (319)
T ss_dssp             CSSCEEEEECCCSSS------------THHHHHHHHHHHHHHHH--------TCEEEEECCSSTTCH----HHHHHHHHH
T ss_pred             CCCCeEEEEecCCCC------------HHHHHHHHHHHHHHHHc--------CCEEEEeCCCCCCCH----HHHHHHHHH
Confidence            356889999984321            24566777887777764        344544433321221    123334444


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   .++|++|+...+.........+...++|+|..+...+...  .....++.+.+++...
T Consensus        58 l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~--~~~~~~~~v~~d~~~~  116 (319)
T 4KQC_A           58 EIN-------------------KNPDAIAFAAVTGDFTEQIKRIKEKNIPLIGFDSGILPDQ--AQGAVLATASTDNRAA  116 (319)
T ss_dssp             HHH-------------------TCCSCEEECCCSSCCHHHHHHHHHTTCCEEEETTCSCGGG--CTTCEEEEEECCHHHH
T ss_pred             HHH-------------------hCCCEEEEcCCCcchHHHHHHHHHCCCCEEEEcCCCCccc--ccCceeEEEEcChHHH
Confidence            432                   4788887654433222334455678999998876433211  0123456677777777


Q NP_000836.2     203 AQAMVDIVTALGWN-----------YVSTLASE-GNYGESGVEAFTQISREIGGVCIA-------QSQKIPREPRPGEFE  263 (908)
Q Consensus       203 ~~~~~~~l~~~~~~-----------~v~ii~~~-~~~~~~~~~~~~~~~~~~~~i~v~-------~~~~~~~~~~~~~~~  263 (908)
                      ++.+++++.+.+.+           +++++... +.....+.++|++.+++.+ ....       .........+..+..
T Consensus       117 g~~~~~~l~~~~~~~i~~~~~~~~~~v~~~~~~~~~~~~~r~~g~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~  195 (319)
T 4KQC_A          117 AAIVADKMFEALKTRIAAFTSDNKAKIAVLQLDNSDTGIGRAEGFVKRFTELA-DGDAATAGKYALQVIVPTTQNEADIA  195 (319)
T ss_dssp             HHHHHHHHHHHHHHHHHTSBTTBCEEEEEECCCSSHHHHHHHHHHHHHHHHHH-HHSTTTTTSEEEEEECCSSSSHHHHH
T ss_pred             HHHHHHHHHHHHHHHhhhcCCCCcEEEEEEEeCCCcchHHHHHHHHHHHHhcc-CcchhhCcceeeEEEccCCCCHHHHH
Confidence            88888877554443           34444422 3345566777877776642 2210       000000001111222


Q NP_000836.2     264 KIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       264 ~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      ..++.+. ..++++|++.. +..+..+++++++.|.
T Consensus       196 ~~~~~l~-~~~~~~i~~~~-~~~a~~~~~a~~~~g~  229 (319)
T 4KQC_A          196 NEVNALR-GKSVLGIYLSN-EAMARGFLVVYKSAEA  229 (319)
T ss_dssp             HHHHTTT-TTTCSEEEECS-HHHHHHHHHHCCBCST
T ss_pred             HHHHHHh-cCCceEEEEcC-HHHHHHHHHHHHhccc
Confidence            3333332 24667777664 4455677777777664


No 287
>4WWH_A ABC TRANSPORTER SOLUTE BINDING PROTEIN; ABC TRANSPORTER SOLUTE BINDING PROTEIN; HET: MSE, TRS, GAL; 1.2A {Mycobacterium smegmatis}
Probab=96.38  E-value=1.8e-05  Score=81.89  Aligned_cols=210  Identities=12%  Similarity=0.038  Sum_probs=113.1  Template_Neff=11.000

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....+..+||++.|..+.            .++.....+++.++++.|          +++.+.+...+.    +...+.
T Consensus        30 ~~~~~~~~Igvv~~~~~~------------~~~~~~~~g~~~~~~~~g----------~~~~~~~~~~~~----~~~~~~   83 (362)
T 4WWH_A           30 GDGDAKGTVGIAMPTKSS------------ERWVADGQNMVDQFKAFG----------YDTDLQYGDDVV----QNQVSQ   83 (362)
T ss_dssp             ----CCCEEEEEECCSSS------------THHHHHHHHHHHHHHHTT----------CEEEEEECTTCH----HHHHHH
T ss_pred             ccCCCCceEEEEcCCCCC------------HHHHHHHhHHHHHHHHhC----------CeEEEeecCccH----HHHHHH
Confidence            345678999999987532            234556677777776643          233344433332    122333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVS-IMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~-~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                   .++|++|........ ......+...++|+|..+...+..     .+..+.+..+
T Consensus        84 ~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~-----~~~~~~v~~d  139 (362)
T 4WWH_A           84 IENMIT-------------------KGVKLLVIAPIDGSSLTNTLQHAADLKIPVISYDRLIKGT-----PNVDYYATFD  139 (362)
T ss_dssp             HHHHHH-------------------TTCSEEEECCSSTTSCHHHHHHHHHTTCCEEEESSCCCSC-----SCCCEEEEEC
T ss_pred             HHHHHh-------------------cCCCEEEEecCChhhhHHHHHHHHHCCCCEEEeCCCCCCC-----CCCcEEEEec
Confidence            443332                   467877764433322 234455667899999877543310     1235566677


Q NP_000836.2     199 DSYQAQAMVDIVTA-------LGWNYVSTLAS--EGNYGESGVEAFTQISREIGG-VCIAQSQK-------IPREPRPGE  261 (908)
Q Consensus       199 ~~~~~~~~~~~l~~-------~~~~~v~ii~~--~~~~~~~~~~~~~~~~~~~~~-i~v~~~~~-------~~~~~~~~~  261 (908)
                      +...++.+++++.+       .+.++|+++..  +......+.++|++.+++.+. ..+.....       .....+..+
T Consensus       140 ~~~~g~~~~~~l~~~~~~~~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  219 (362)
T 4WWH_A          140 NTKVGVLQANYIVDTLGVADGKGPFNLELFAGSPDDNNATYFFQGAMSVLQPYIDSGKLVVKSGQTTFDQIATLRWDGGL  219 (362)
T ss_dssp             HHHHHHHHHHHHHHHHTGGGTCCCEEEEECBCCTTCTHHHHHHHHHHHHHHHHHHHTSEECTTCCCSHHHHBCGGGCHHH
T ss_pred             HHHHHHHHHHHHHHHhCCcCCCCCeEEEEEECCCCChhHHHHHHHHHHHhHhhccCCeEEEeeCccccccccccCCCHHH
Confidence            77777888887754       46778998874  233455667778777765421 11211100       000011122


Q NP_000836.2     262 FEKIIKRLLET----PNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       262 ~~~~~~~l~~~----~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ....+++++..    .++++|++.. +..+..+++++++.|+.
T Consensus       220 ~~~~~~~~l~~~~~~~~~daii~~~-~~~a~~~~~al~~~g~~  261 (362)
T 4WWH_A          220 AQSRMDNLLSQAYTSGRVDAVLSPY-DGISRGVISALKSAGYG  261 (362)
T ss_dssp             HHHHHHHCCCCCCSSSCCCEEECSS-HHHHHHHHHHHHHTTCS
T ss_pred             HHHHHHHHHHHHhcCCCccEEEeCC-hHHHHHHHHHHHHCCCC
Confidence            34445555421    2567777654 34466677788777763


No 288
>3CS3_A Sugar-binding transcriptional regulator, LacI family; STRUCTURAL GENOMICS, SUGAR-BINDING TRANSCRIPTIONAL REGULATOR; HET: SO4; 2.4A {Enterococcus faecalis}
Probab=96.37  E-value=1.8e-05  Score=78.05  Aligned_cols=194  Identities=11%  Similarity=0.015  Sum_probs=113.5  Template_Neff=11.600

Q NP_000836.2      42 VDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQ  121 (908)
Q Consensus        42 ~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~  121 (908)
                      .++..+||++.|..+.            .++.....+++.++++.        |+++  .+.+...+        .   +
T Consensus         5 ~~~~~~Ig~i~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~~--~~~~~~~~--------~---~   51 (277)
T 3CS3_A            5 RRQTNIIGVYLADYGG------------SFYGELLEGIKKGLALF--------DYEM--IVCSGKKS--------H---L   51 (277)
T ss_dssp             CCCCCEEEEEECSSCT------------TTHHHHHHHHHHHHHTT--------TCEE--EEEESTTT--------T---T
T ss_pred             cCCCCEEEEEECCCCC------------chHHHHHHHHHHHHHhc--------CCEE--EEEeCCch--------h---h
Confidence            3567899999986432            25566777888777764        2333  33332211        0   1


Q NP_000836.2     122 ALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSY  201 (908)
Q Consensus       122 ~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~  201 (908)
                      .+..                   ++++++|...... .......+...++|+|..+...+.       +..+++..++..
T Consensus        52 ~~~~-------------------~~~d~ii~~~~~~-~~~~~~~~~~~~ip~v~~~~~~~~-------~~~~~v~~d~~~  104 (277)
T 3CS3_A           52 FIPE-------------------KMVDGAIILDWTF-PTKEIEKFAERGHSIVVLDRTTEH-------RNIRQVLLDNRG  104 (277)
T ss_dssp             CCCT-------------------TTCSEEEEECTTS-CHHHHHHHHHTTCEEEESSSCCCS-------TTEEEEEECHHH
T ss_pred             cccc-------------------cccCEEEEeCCCC-ChHHHHHHHHCCCeEEEECCCCCc-------cCCcEEEeCcHH
Confidence            1111                   4678777633222 223445566789999988764431       345677777777


Q NP_000836.2     202 QAQAMVDIVTALGWNYVSTLASEGN--YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET--PNARA  277 (908)
Q Consensus       202 ~~~~~~~~l~~~~~~~v~ii~~~~~--~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~--~~~~v  277 (908)
                      .++.+++++.+.+.++++++.....  ....+.+++++.+++. ++++... ...  .+..+....++++++.  .++++
T Consensus       105 ~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~-~~~--~~~~~~~~~~~~~l~~~~~~~~~  180 (277)
T 3CS3_A          105 GATQAIEQFVNVGSKKVLLLSGPEKGYDSQERLAVSTRELTRF-GIPYEII-QGD--FTEPSGYAAAKKILSQPQTEPVD  180 (277)
T ss_dssp             HHHHHHHHHHHTTCSCEEEEECCTTSHHHHHHHHHHHHHHHHT-TCCEEEE-ECC--SSHHHHHHHHHHHTTSCCCSSEE
T ss_pred             HHHHHHHHHHHCCCCeEEEEcCCCCCCCHHHHHHHHHHHHHHc-CCCCeEE-ecC--CChHHHHHHHHHHHcCCCCCCcE
Confidence            8888888886667889999885432  4566778888887764 3443211 111  1112333445555432  25677


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++. ++..+..+++++++.|+.
T Consensus       181 i~~~-~~~~a~~~~~~l~~~g~~  202 (277)
T 3CS3_A          181 VFAF-NDEMAIGVYKYVAETNYQ  202 (277)
T ss_dssp             EEES-SHHHHHHHHHHHTTSSCC
T ss_pred             EEEe-CHHHHHHHHHHHHHCCCC
Confidence            5554 455567788888877764


No 289
>2H0A_A Transcriptional regulator; Transcription, regulator, repressor, Structural Genomics; 2.8A {Thermus thermophilus}
Probab=96.30  E-value=2.4e-05  Score=76.97  Aligned_cols=144  Identities=12%  Similarity=0.039  Sum_probs=83.5  Template_Neff=12.000

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++|++|........ .....+...++|+|..+...         +.++.+..++...++.+++++.+.+.++++++..+
T Consensus        54 ~~~d~ii~~~~~~~~-~~~~~~~~~~ipvv~~~~~~---------~~~~~v~~d~~~~~~~~~~~l~~~g~~~i~~~~~~  123 (276)
T 2H0A_A           54 YLTDGLILASYDLTE-RFEEGRLPTERPVVLVDAQN---------PRYDSVYLDNRLGGRLAGAYLARFPGPIFAIAVEE  123 (276)
T ss_dssp             CCCSEEEEESCCCC-------CCSCSSCEEEESSCC---------TTSEEEEECSHHHHHHHHHHHTTSSSCEEEEEECC
T ss_pred             hcCCEEEEeccCCCh-HHHHccCCcCCCEEEECCCC---------CCCCEEEEChHHHHHHHHHHHHhCCCCEEEEEeCC
Confidence            478888865433322 23344566799999876542         23456667777778888888876688889888743


Q NP_000836.2     225 -------GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET-PNARAVIMFANEDDIRRILEAAKK  296 (908)
Q Consensus       225 -------~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~-~~~~viv~~~~~~~~~~~l~~~~~  296 (908)
                             ..+...+.+++++.+++. ++.+.....+....+..+....++++++. .++++|++.. +..+..+++++++
T Consensus       124 ~~~~~~~~~~~~~r~~~~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~i~~~~-~~~a~~~~~~~~~  201 (276)
T 2H0A_A          124 EPDRAFRRTVFAERMAGFQEALKEA-GRPFSPDRLYITRHSQEGGRLALRHFLEKASPPLNVFAGA-DQVALGVLEEAVR  201 (276)
T ss_dssp             SCCC---CCHHHHHHHHHHHHHHHT-TCCCCGGGEEEECSSHHHHHHHHHHHHTTCCSSEEEECSS-HHHHHHHHHHHHT
T ss_pred             CCchHhhhhHHHHHHHHHHHHHHHc-CCCCChhheEEecCChHHHHHHHHHHHHhcCCCCEEEECC-HHHHHHHHHHHHH
Confidence                   234556778888888765 34432211111001112233444555421 2477776653 4456678888888


Q NP_000836.2     297 LNQS  300 (908)
Q Consensus       297 ~g~~  300 (908)
                      .|+.
T Consensus       202 ~g~~  205 (276)
T 2H0A_A          202 LGLT  205 (276)
T ss_dssp             TSCT
T ss_pred             CCCC
Confidence            7764


No 290
>3E61_B Putative transcriptional repressor of ribose; STRUCTURAL GENOMICS, TRANSCRIPTION, DNA-binding, Transcription; HET: GOL; 2.0A {Staphylococcus saprophyticus subsp. saprophyticus}
Probab=96.28  E-value=2.5e-05  Score=77.04  Aligned_cols=197  Identities=11%  Similarity=0.029  Sum_probs=106.2  Template_Neff=11.300

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++.+||++.|..+.            .+......+++.++++.+        +  ++.+.+...+.    ....+.+
T Consensus         4 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~   57 (277)
T 3E61_B            4 YKRKSKLIGLLLPDMSN------------PFFTLIARGVEDVALAHG--------Y--QVLIGNSDNDI----KKAQGYL   57 (277)
T ss_dssp             ------CEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------C--CEEEEECTTCH----HHHHHHH
T ss_pred             CCCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHCC--------C--eEEEEeCCCCH----HHHHHHH
Confidence            34567899999986432            245567777777776642        2  33344433321    2223344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   .++|++|....+..  .....+...++|+|..+...+         ....+..++.
T Consensus        58 ~~l~~-------------------~~~d~ii~~~~~~~--~~~~~~~~~~ipvv~~~~~~~---------~~~~v~~d~~  107 (277)
T 3E61_B           58 ATFVS-------------------HNCTGMISTAFNEN--IIENTLTDHHIPFVFIDRINN---------EHNGISTNHF  107 (277)
T ss_dssp             HHHHH-------------------TTCSEEEECGGGHH--HHHHHHHHTTCCEEECC---------------CBCCCCHH
T ss_pred             HHHHH-------------------cCCCEEEEeCCCch--HHHHHHHHCCCCEEEECCCCC---------CCCEEEeChH
Confidence            43332                   47888876543322  223455678999998775432         2345666667


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ..++.+++++.+.+.++++++....  .....+.+++++.+++. ++.+.... ..   .........+.+. ..++++|
T Consensus       108 ~~~~~~~~~l~~~~~~~v~~~~~~~~~~~~~~r~~~~~~~~~~~-~~~~~~~~-~~---~~~~~~~~~~~l~-~~~~~ai  181 (277)
T 3E61_B          108 KGGQLQAEVVRKGKGKNVLIVHENLLIDAFHQRVQGIKYILDQQ-RIDYKMLE-AT---LLDNDKKFIDLIK-ELSIDSI  181 (277)
T ss_dssp             HHHHHHHHHHHHTTCSEEEEEECCTTSHHHHHHHHHHHHHHHHT-TCEEEEEE-GG---GGSSHHHHHHHHH-HTTCCEE
T ss_pred             HHHHHHHHHHHcCCCCeEEEEeCCCCChHHHHHHHHHHHHHHHC-CCChHHHh-hh---cccchHHHHHHHh-hCCCCEE
Confidence            7777788887665667888887532  34556777888777764 34332111 11   0111222222232 2467888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|..
T Consensus       182 ~~~~-d~~a~~~~~al~~~g~~  202 (277)
T 3E61_B          182 ICSN-DLLAINVLGIVQRYHFK  202 (277)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHcCCC
Confidence            7764 44566777888777763


No 291
>3E61_A Putative transcriptional repressor of ribose; STRUCTURAL GENOMICS, TRANSCRIPTION, DNA-binding, Transcription; HET: GOL; 2.0A {Staphylococcus saprophyticus subsp. saprophyticus}
Probab=96.28  E-value=2.5e-05  Score=77.04  Aligned_cols=197  Identities=11%  Similarity=0.029  Sum_probs=101.8  Template_Neff=11.300

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...++.+||++.|..+.            .+......+++.++++.+        +  ++.+.+...+.    ....+.+
T Consensus         4 ~~~~~~~Ig~i~~~~~~------------~~~~~~~~~~~~~~~~~g--------~--~~~~~~~~~~~----~~~~~~~   57 (277)
T 3E61_A            4 YKRKSKLIGLLLPDMSN------------PFFTLIARGVEDVALAHG--------Y--QVLIGNSDNDI----KKAQGYL   57 (277)
T ss_dssp             ------CEEEEESCTTS------------HHHHHHHHHHHHHHHHTT--------C--CEEEEECTTCH----HHHHHHH
T ss_pred             CCCCCCEEEEEeCCCCC------------HHHHHHHHHHHHHHHHCC--------C--eEEEEeCCCCH----HHHHHHH
Confidence            34567899999986432            245567777777776642        2  33344433321    2223344


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   .++|++|....+..  .....+...++|+|..+...+         ....+..++.
T Consensus        58 ~~l~~-------------------~~~d~ii~~~~~~~--~~~~~~~~~~ipvv~~~~~~~---------~~~~v~~d~~  107 (277)
T 3E61_A           58 ATFVS-------------------HNCTGMISTAFNEN--IIENTLTDHHIPFVFIDRINN---------EHNGISTNHF  107 (277)
T ss_dssp             HHHHH-------------------TTCSEEEECGGGHH--HHHHHHHHC-CCEEEGGGCC------------------HH
T ss_pred             HHHHH-------------------cCCCEEEEeCCCch--HHHHHHHHCCCCEEEECCCCC---------CCCEEEeChH
Confidence            43332                   47888876543322  223455678999998775432         2345666667


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      ..++.+++++.+.+.++++++....  .....+.+++++.+++. ++.+.... ..   .........+.+. ..++++|
T Consensus       108 ~~~~~~~~~l~~~~~~~v~~~~~~~~~~~~~~r~~~~~~~~~~~-~~~~~~~~-~~---~~~~~~~~~~~l~-~~~~~ai  181 (277)
T 3E61_A          108 KGGQLQAEVVRKGKGKNVLIVHENLLIDAFHQRVQGIKYILDQQ-RIDYKMLE-AT---LLDNDKKFIDLIK-ELSIDSI  181 (277)
T ss_dssp             HHHHHHHHHHHHTTCCSEEEEESCTTSHHHHHHHHHHHHHHHC----CEEEEE-GG---GGGSHHHHHHHHH-HHTCCEE
T ss_pred             HHHHHHHHHHHcCCCCeEEEEeCCCCChHHHHHHHHHHHHHHHC-CCChHHHh-hh---cccchHHHHHHHh-hCCCCEE
Confidence            7777788887665667888887532  34556777888777764 34332111 11   0111222222232 2467888


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++.. +..+..+++++++.|..
T Consensus       182 ~~~~-d~~a~~~~~al~~~g~~  202 (277)
T 3E61_A          182 ICSN-DLLAINVLGIVQRYHFK  202 (277)
T ss_dssp             EESS-HHHHHHHHHHHHHTTCC
T ss_pred             EECC-HHHHHHHHHHHHHcCCC
Confidence            7764 44566777888777763


No 292
>6HNI_A ABC-type transport system, sugar-family extracellular; Substrate binding protein, adhesin, tyrosine; HET: TYR, EDO; 1.35A {Peptoclostridium difficile 630}
Probab=96.19  E-value=3.4e-05  Score=77.89  Aligned_cols=218  Identities=9%  Similarity=0.062  Sum_probs=114.9  Template_Neff=11.800

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....+.++||++.|.++             .++.....+++.++++.+..    .|+++++.+.|...+.    ....+
T Consensus        17 ~~~~~~~~~Igvv~~~~~-------------~~~~~~~~g~~~~~~~~g~~----~g~~i~~~~~~~~~~~----~~~~~   75 (319)
T 6HNI_A           17 NSKDKEVKKIGITQLVEH-------------PALDATRTGFVKALEKNGFK----DGENIDIDFQNAQNDM----PTTQS   75 (319)
T ss_pred             HhhcCCceEEEEEecCCC-------------HHHHHHHHHHHHHHHHhCCC----CCceEEEEEECCCCCH----HHHHH
Confidence            345667899999998653             24556777777777664321    1345666666654332    22233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN---TRYDFFSRV  195 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~---~~~~~~~~~  195 (908)
                      .++++..                   .++|++|+...... .....  ...++|+|..+...+.....   ...++.+.+
T Consensus        76 ~~~~~~~-------------------~~~d~ii~~~~~~~-~~~~~--~~~~ipvv~~~~~~~~~~~~~~~~~~~~~~~~  133 (319)
T 6HNI_A           76 IASKFAS-------------------DKKDLIFAISTPSA-QAAFN--ATKDIPILITAVSDPVAAGLVKTLEKPGTNVS  133 (319)
T ss_pred             HHHHHHH-------------------CCCCEEEEeCCchH-HHHHH--HHcCCCEEEEcCCCCCccccccCCCCCCcCee
Confidence            3333322                   47888876443322 22222  25799998876544321100   001122444


Q NP_000836.2     196 VPPDSYQAQAMVDIVTAL--GWNYVSTLASEGNYG-ESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~--~~~~v~ii~~~~~~~-~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      ..+....++.+++++.+.  +.++++++..+...+ ..+.+++++.+++. ++++.....    .+..+....++++.  
T Consensus       134 ~~~~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~----~~~~~~~~~i~~~~--  206 (319)
T 6HNI_A          134 GTSDFVSVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKN-GFKVVEKGI----TTSNEVNQGISSLV--  206 (319)
T ss_pred             ecCHHHHHHHHHHHHHHHCCCCcEEEEEeCCCChHHHHHHHHHHHHHHcC-CCEEeeeeC----CCHHHHHHHHHHhC--
Confidence            455555566677777554  788999998544332 34566777776654 344432111    11122334444442  


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIG  307 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~  307 (908)
                      .++++|++.. +..+..+++++++.+...++.+++
T Consensus       207 ~~~~~i~~~~-~~~a~~~~~~~~~~~~~~~v~v~~  240 (319)
T 6HNI_A          207 GKIDVLYVPT-DNLVASSMPIVSKIATENKIPVIA  240 (319)
T ss_pred             CCCCEEEECC-hHHHHHHHHHHHHCCCCCCceEEE
Confidence            3678887664 334556666776665532333443


No 293
>6HNJ_A ABC-type transport system, sugar-family extracellular; Substrate binding protein, adhesin, tyrosine; HET: PGE, EDO; 1.8A {Peptoclostridium difficile 630}
Probab=96.19  E-value=3.4e-05  Score=77.89  Aligned_cols=218  Identities=9%  Similarity=0.062  Sum_probs=114.9  Template_Neff=11.800

Q NP_000836.2      39 SIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLT  118 (908)
Q Consensus        39 ~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~  118 (908)
                      .....+.++||++.|.++             .++.....+++.++++.+..    .|+++++.+.|...+.    ....+
T Consensus        17 ~~~~~~~~~Igvv~~~~~-------------~~~~~~~~g~~~~~~~~g~~----~g~~i~~~~~~~~~~~----~~~~~   75 (319)
T 6HNJ_A           17 NSKDKEVKKIGITQLVEH-------------PALDATRTGFVKALEKNGFK----DGENIDIDFQNAQNDM----PTTQS   75 (319)
T ss_pred             HhhcCCceEEEEEecCCC-------------HHHHHHHHHHHHHHHHhCCC----CCceEEEEEECCCCCH----HHHHH
Confidence            345667899999998653             24556777777777664321    1345666666654332    22233


Q NP_000836.2     119 FVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN---TRYDFFSRV  195 (908)
Q Consensus       119 ~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~---~~~~~~~~~  195 (908)
                      .++++..                   .++|++|+...... .....  ...++|+|..+...+.....   ...++.+.+
T Consensus        76 ~~~~~~~-------------------~~~d~ii~~~~~~~-~~~~~--~~~~ipvv~~~~~~~~~~~~~~~~~~~~~~~~  133 (319)
T 6HNJ_A           76 IASKFAS-------------------DKKDLIFAISTPSA-QAAFN--ATKDIPILITAVSDPVAAGLVKTLEKPGTNVS  133 (319)
T ss_pred             HHHHHHH-------------------CCCCEEEEeCCchH-HHHHH--HHcCCCEEEEcCCCCCccccccCCCCCCcCee
Confidence            3333322                   47888876443322 22222  25799998876544321100   001122444


Q NP_000836.2     196 VPPDSYQAQAMVDIVTAL--GWNYVSTLASEGNYG-ESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLET  272 (908)
Q Consensus       196 ~~~~~~~~~~~~~~l~~~--~~~~v~ii~~~~~~~-~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~  272 (908)
                      ..+....++.+++++.+.  +.++++++..+...+ ..+.+++++.+++. ++++.....    .+..+....++++.  
T Consensus       134 ~~~~~~~~~~~~~~l~~~~~~~~~i~~i~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~~----~~~~~~~~~i~~~~--  206 (319)
T 6HNJ_A          134 GTSDFVSVDKGLELLKIFAPKAKTIGVMYNTSEVNSKVQVDALKEYASKN-GFKVVEKGI----TTSNEVNQGISSLV--  206 (319)
T ss_pred             ecCHHHHHHHHHHHHHHHCCCCcEEEEEeCCCChHHHHHHHHHHHHHHcC-CCEEeeeeC----CCHHHHHHHHHHhC--
Confidence            455555566677777554  788999998544332 34566777776654 344432111    11122334444442  


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLNQSGHFLWIG  307 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g~~~~~~~i~  307 (908)
                      .++++|++.. +..+..+++++++.+...++.+++
T Consensus       207 ~~~~~i~~~~-~~~a~~~~~~~~~~~~~~~v~v~~  240 (319)
T 6HNJ_A          207 GKIDVLYVPT-DNLVASSMPIVSKIATENKIPVIA  240 (319)
T ss_pred             CCCCEEEECC-hHHHHHHHHHHHHCCCCCCceEEE
Confidence            3678887664 334556666776665532333443


No 294
>3H75_A Periplasmic sugar-binding domain protein; Protein Structure Initiative II (PSI; HET: SO4; 1.6A {Pseudomonas fluorescens Pf-5}
Probab=96.16  E-value=3.8e-05  Score=78.89  Aligned_cols=212  Identities=15%  Similarity=0.069  Sum_probs=109.7  Template_Neff=10.900

Q NP_000836.2      44 GDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQAL  123 (908)
Q Consensus        44 ~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l  123 (908)
                      ..++||++.|....           ..+...+..+++.++++.+        +  ++.+.+...++    ....+.++++
T Consensus         2 ~~~~I~~i~~~~~~-----------~~~~~~~~~g~~~~a~~~g--------~--~~~~~~~~~~~----~~~~~~~~~l   56 (350)
T 3H75_A            2 SLTSVVFLNPGNST-----------ETFWVSYSQFMQAAARDLG--------L--DLRILYAERDP----QNTLQQAREL   56 (350)
T ss_dssp             -CCEEEEEECSCTT-----------CHHHHHHHHHHHHHHHHHT--------C--EEEEEECTTCH----HHHHHHHHHH
T ss_pred             CCeEEEEEcCCCCC-----------CHHHHHHHHHHHHHHHHhC--------C--EEEEEEcCCCH----HHHHHHHHHH
Confidence            46789999986211           1245667777777777642        2  33444443332    1222333333


Q NP_000836.2     124 IEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSD-------NTRYDFFSRVV  196 (908)
Q Consensus       124 ~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~-------~~~~~~~~~~~  196 (908)
                      +..                 ..++|++|..............+...+||+|..+...+....       ....+++..+.
T Consensus        57 ~~~-----------------~~~~d~ii~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~~~~~~~~~~~~~~~~~~~~v~  119 (350)
T 3H75_A           57 FQG-----------------RDKPDYLMLVNEQYVAPQILRLSQGSGIKLFIVNSPLTLDQRELIGQSRQNYSDWIGSMV  119 (350)
T ss_dssp             HHS-----------------SSCCSEEEEECCSSHHHHHHHHHTTSCCEEEEEESCCCTTTC------------CEEEEE
T ss_pred             HcC-----------------CCCCCEEEEeCCcccHHHHHHHHHhcCCeEEEECCCCCHHHHHHhcCcchhcccchhEee
Confidence            210                 046788776543322223445566789999987754332100       00012345666


Q NP_000836.2     197 PPDSYQAQAMVDIVTA-LGWN------YVSTLAS--EGNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIK  267 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~-~~~~------~v~ii~~--~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~  267 (908)
                      .++...+..+++++.+ .+.+      +++++..  +......+.++|++.+++.+...+.... .. ..+..+....++
T Consensus       120 ~d~~~~g~~~~~~l~~~~g~~~~~~~~~i~~i~~~~~~~~~~~r~~g~~~~l~~~~~~~~~~~~-~~-~~~~~~~~~~~~  197 (350)
T 3H75_A          120 GDDEEAGYRMLKELLHKLGPVPAGHGIELLAFSGLKVTPAAQLRERGLRRALAEHPQVHLRQLV-YG-EWNRERAYRQAQ  197 (350)
T ss_dssp             CCHHHHHHHHHHHHHHHHCCCCSSCCEEEEEEESCTTSHHHHHHHHHHHHHHHHCTTEEEEEEE-EC-TTCHHHHHHHHH
T ss_pred             CCHHHHHHHHHHHHHHHhCCCCCCCCcEEEEEeCCCCCHHHHHHHHHHHHHHHhCCCeEEEEEE-eC-CCCHHHHHHHHH
Confidence            6777777777777643 4432      6777764  2334556778888887764312221111 11 011122334445


Q NP_000836.2     268 RLLE-TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       268 ~l~~-~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ++++ ..++++|++.. +..+..+++++++.|+.
T Consensus       198 ~~l~~~~~~~~i~~~~-d~~a~~~~~al~~~g~~  230 (350)
T 3H75_A          198 QLLKRYPKTQLVWSAN-DEMALGAMQAARELGRK  230 (350)
T ss_dssp             HHHHHCTTEEEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             HHHHHCCCCcEEEECC-HHHHHHHHHHHHHcCCC
Confidence            5542 12466666553 44566778888887764


No 295
>4RKQ_A Transcriptional regulator, LacI family; sugar binding, transcription regulation, Enzyme; HET: EDO; 1.903A {Arthrobacter sp.}
Probab=96.09  E-value=4.6e-05  Score=75.83  Aligned_cols=199  Identities=12%  Similarity=0.049  Sum_probs=110.8  Template_Neff=11.600

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++..+||++.|..+.            .+...+..+++.++++.+        +  ++.+.+...++.    ...+.
T Consensus        10 l~~~~~~~I~~i~~~~~~------------~~~~~~~~~~~~~~~~~g--------~--~~~~~~~~~~~~----~~~~~   63 (294)
T 4RKQ_A           10 LVQGARTSVGLAIPDLTN------------PYFPAFASSVVELATLRG--------W--HVVVDDYGHGGR----SGLDA   63 (294)
T ss_dssp             SCCSCCCEEEEEESCSSS------------THHHHHHHHHHHHHHHTT--------C--EEEEEECCSTTC----CHHHH
T ss_pred             HccCCCCeEEEEeCCCCC------------ccHHHHHHHHHHHHHHcC--------C--eEEEEeCCCChh----hHHHH
Confidence            345678999999986432            245566777777766542        2  334444333221    22223


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      ++.+ .                   +++|++|....+... .... . ..++|+|..+...+        +..+.+..+.
T Consensus        64 ~~~~-~-------------------~~~d~ii~~~~~~~~-~~~~-~-~~~ipvv~~~~~~~--------~~~~~v~~d~  112 (294)
T 4RKQ_A           64 VEHL-A-------------------PQVDAVIGYLGGYAD-QAQT-V-LGRRPLIVLDENPG--------GAAGSINFDY  112 (294)
T ss_dssp             HHHH-G-------------------GGCSEEEECCTTCHH-HHHH-H-HTTSCEEEESSCCT--------TCSEEEEECH
T ss_pred             HHHH-h-------------------hcCCEEEEeCCCchh-HHHH-H-hcCCCEEEECCCCC--------CCCCEEEeCH
Confidence            3322 1                   467887764333221 1111 2 46899988765332        2455667777


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGN-------YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-  271 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~-------~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-  271 (908)
                      ...++.+++++.+.+.++++++..+..       +...+.+++.+.+++. ++.+... ...  .+..+....+++++. 
T Consensus       113 ~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~-~~~--~~~~~~~~~~~~~l~~  188 (294)
T 4RKQ_A          113 QHAAKVAVAQLMDSKRQHIAYLEAGSASESDEPVPCTVRGKAVAGRLDEL-GASWSLI-VAE--ETAEAAREAAAAFLRE  188 (294)
T ss_dssp             HHHHHHHHHHHHHTTCSSEEEEEESCCTTSSSCCCCSHHHHHHHHHHHHT-TCCEEEE-EEC--SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHCCCCeEEEEecCCCCCCCCCCcchHHHHHHHHHHHHh-CCCceEE-ecC--ccHHHHHHHHHHHHHH
Confidence            777888888876667889999885332       3456667777777765 3433211 111  111223344444442 


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ..++++|++.. +..+..+++++++.|+.
T Consensus       189 ~~~~~~i~~~~-~~~a~~~~~al~~~g~~  216 (294)
T 4RKQ_A          189 HPETDGILAFN-DLMAAGVLKALSGSGRR  216 (294)
T ss_dssp             CTTCCEEEESS-HHHHHHHHHHHHHTTCC
T ss_pred             CCCCcEEEECC-HHHHHHHHHHHHHCCCC
Confidence            12467776653 44566778888887764


No 296
>4RKQ_B Transcriptional regulator, LacI family; sugar binding, transcription regulation, Enzyme; HET: EDO; 1.903A {Arthrobacter sp.}
Probab=96.09  E-value=4.6e-05  Score=75.83  Aligned_cols=199  Identities=12%  Similarity=0.049  Sum_probs=108.6  Template_Neff=11.600

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ...++..+||++.|..+.            .+...+..+++.++++.+        +  ++.+.+...++.    ...+.
T Consensus        10 l~~~~~~~I~~i~~~~~~------------~~~~~~~~~~~~~~~~~g--------~--~~~~~~~~~~~~----~~~~~   63 (294)
T 4RKQ_B           10 LVQGARTSVGLAIPDLTN------------PYFPAFASSVVELATLRG--------W--HVVVDDYGHGGR----SGLDA   63 (294)
T ss_dssp             ----CCCEEEEEESCSSS------------THHHHHHHHHHHHHHHTT--------C--EEEEEECCSTTC----CHHHH
T ss_pred             HccCCCCeEEEEeCCCCC------------ccHHHHHHHHHHHHHHcC--------C--eEEEEeCCCChh----hHHHH
Confidence            345678999999986432            245566777777766542        2  334444333221    22223


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      ++.+ .                   +++|++|....+... .... . ..++|+|..+...+        +..+.+..+.
T Consensus        64 ~~~~-~-------------------~~~d~ii~~~~~~~~-~~~~-~-~~~ipvv~~~~~~~--------~~~~~v~~d~  112 (294)
T 4RKQ_B           64 VEHL-A-------------------PQVDAVIGYLGGYAD-QAQT-V-LGRRPLIVLDENPG--------GAAGSINFDY  112 (294)
T ss_dssp             HHHH-G-------------------GGCSEEEECCSSCHH-HHHH-H-HTTSCEEEESSCCT--------TCSEEEEECH
T ss_pred             HHHH-h-------------------hcCCEEEEeCCCchh-HHHH-H-hcCCCEEEECCCCC--------CCCCEEEeCH
Confidence            3322 1                   467887764333221 1111 2 46899988765332        2455667777


Q NP_000836.2     200 SYQAQAMVDIVTALGWNYVSTLASEGN-------YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-  271 (908)
Q Consensus       200 ~~~~~~~~~~l~~~~~~~v~ii~~~~~-------~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-  271 (908)
                      ...++.+++++.+.+.++++++..+..       +...+.+++.+.+++. ++.+... ...  .+..+....+++++. 
T Consensus       113 ~~~~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~-~~~--~~~~~~~~~~~~~l~~  188 (294)
T 4RKQ_B          113 QHAAKVAVAQLMDSKRQHIAYLEAGSASESDEPVPCTVRGKAVAGRLDEL-GASWSLI-VAE--ETAEAAREAAAAFLRE  188 (294)
T ss_dssp             HHHHHHHHHHHHHTTCCSEEEEEECC------CCCCSHHHHHHHHHHHHH-TCCEEEE-EEC--SSHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHCCCCeEEEEecCCCCCCCCCCcchHHHHHHHHHHHHh-CCCceEE-ecC--ccHHHHHHHHHHHHHH
Confidence            777888888876667889999885332       3456667777777765 3433211 111  111223344444442 


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ..++++|++.. +..+..+++++++.|+.
T Consensus       189 ~~~~~~i~~~~-~~~a~~~~~al~~~g~~  216 (294)
T 4RKQ_B          189 HPETDGILAFN-DLMAAGVLKALSGSGRR  216 (294)
T ss_dssp             CTTCCEEEESS-HHHHHHHHHHHHHHTCC
T ss_pred             CCCCcEEEECC-HHHHHHHHHHHHHCCCC
Confidence            12467776653 44566778888887764


No 297
>3LFT_A uncharacterized protein; ABC, ATPase, cassette, L-Trp, PSI; HET: TRP; 1.35A {Streptococcus pneumoniae}
Probab=96.03  E-value=5.4e-05  Score=75.11  Aligned_cols=202  Identities=15%  Similarity=0.156  Sum_probs=105.7  Template_Neff=12.200

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      ..+||++.|.+.             .++....++++.++++.+..     |.++++.+.|+..++.    ...+.++++.
T Consensus         2 ~~~I~~i~~~~~-------------~~~~~~~~~~~~~~~~~g~~-----~~~~~~~~~d~~~~~~----~~~~~~~~~~   59 (295)
T 3LFT_A            2 NAKIGVLQFVSH-------------PSLDLIYKGIQDGLAEEGYK-----DDQVKIDFMNSEGDQS----KVATMSKQLV   59 (295)
T ss_dssp             CEEEEEEECSCC-------------HHHHHHHHHHHHHHHHTTCC-----GGGEEEEEEECTTCHH----HHHHHHHHHT
T ss_pred             CcEEEEEEccCC-------------HHHHHHHHHHHHHHHHcCCc-----cCeEEEEEECCCCCHH----HHHHHHHHHH
Confidence            568999988742             25567788888888876422     2346666666543322    2223333332


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN---TRYDFFSRVVPPDSY  201 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~---~~~~~~~~~~~~~~~  201 (908)
                      .                   .++|++|+.... ....+.. + ..++|+|..+...+.....   ...+..+.+..+...
T Consensus        60 ~-------------------~~~d~ii~~~~~-~~~~~~~-~-~~~ipvv~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  117 (295)
T 3LFT_A           60 A-------------------NGNDLVVGIATP-AAQGLAS-A-TKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHN  117 (295)
T ss_dssp             T-------------------SSCSEEEEESHH-HHHHHHH-H-CSSSCEEEESCSCTTTTTSCSCSSCCCSSEEEEEECC
T ss_pred             H-------------------CCCCEEEEeCCH-HHHHHHH-h-cCCCCEEEEEcCChhhcchhhhccCCCCCcceecCCC
Confidence            2                   478888864332 2222222 2 5799998876544321100   000111223333334


Q NP_000836.2     202 QAQAMVDIVTAL--GWNYVSTLASEGNYG-ESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~--~~~~v~ii~~~~~~~-~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      .++.+++++.+.  +.+++++++.+..++ ..+.+++++.+++. ++++.... ..   +..+....++++.  .++++|
T Consensus       118 ~~~~~~~~l~~~~~~~~~v~~l~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~-~~---~~~~~~~~~~~~~--~~~~~i  190 (295)
T 3LFT_A          118 PAQQQVELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKA-GLTVETFA-VP---STNEIASTVTVMT--SKVDAI  190 (295)
T ss_dssp             CHHHHHHHHHHHCTTCCEEEEEEETTCHHHHHHHHHHHHHHHHT-TCEEEEEE-ES---SGGGHHHHHHHHT--TTCSEE
T ss_pred             cHHHHHHHHHHHCCCCcEEEEeecCCCCChHHHHHHHHHHHHHc-CCEEEEEE-eC---CHHHHHHHHHHhc--cCCCEE
Confidence            455666666554  678899998654433 45667777777664 34443211 11   1123444444442  367777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g  298 (908)
                      ++.. +..+..+++++.+.+
T Consensus       191 ~~~~-~~~~~~~~~~~~~~~  209 (295)
T 3LFT_A          191 WVPI-DNTIASGFPTVVSSN  209 (295)
T ss_dssp             EECS-CHHHHHTHHHHHHHT
T ss_pred             EECC-ChhhhcchhHHHHHH
Confidence            6654 333444555555544


No 298
>3LFT_B uncharacterized protein; ABC, ATPase, cassette, L-Trp, PSI; HET: MSE, TRP; 1.35A {Streptococcus pneumoniae}
Probab=96.03  E-value=5.4e-05  Score=75.11  Aligned_cols=202  Identities=15%  Similarity=0.156  Sum_probs=103.1  Template_Neff=12.200

Q NP_000836.2      45 DIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQALI  124 (908)
Q Consensus        45 ~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~l~  124 (908)
                      ..+||++.|.+.             .++....++++.++++.+..     |.++++.+.|+..++.    ...+.++++.
T Consensus         2 ~~~I~~i~~~~~-------------~~~~~~~~~~~~~~~~~g~~-----~~~~~~~~~d~~~~~~----~~~~~~~~~~   59 (295)
T 3LFT_B            2 NAKIGVLQFVSH-------------PSLDLIYKGIQDGLAEEGYK-----DDQVKIDFMNSEGDQS----KVATMSKQLV   59 (295)
T ss_dssp             --CEEEEECSCC-------------HHHHHHHHHHHHHHHHTTC---------CCEEEEECTTCHH----HHHHHHHHHH
T ss_pred             CcEEEEEEccCC-------------HHHHHHHHHHHHHHHHcCCc-----cCeEEEEEECCCCCHH----HHHHHHHHHH
Confidence            568999988742             25567788888888876422     2346666666543322    2223333332


Q NP_000836.2     125 EKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDN---TRYDFFSRVVPPDSY  201 (908)
Q Consensus       125 ~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~---~~~~~~~~~~~~~~~  201 (908)
                      .                   .++|++|+.... ....+.. + ..++|+|..+...+.....   ...+..+.+..+...
T Consensus        60 ~-------------------~~~d~ii~~~~~-~~~~~~~-~-~~~ipvv~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  117 (295)
T 3LFT_B           60 A-------------------NGNDLVVGIATP-AAQGLAS-A-TKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHN  117 (295)
T ss_dssp             H-------------------SSCSEEEEESHH-HHHHHHH-H-CSSSCEEEESCSCTTTTTSCSCSSCCCSSEEEEEECC
T ss_pred             H-------------------CCCCEEEEeCCH-HHHHHHH-h-cCCCCEEEEEcCChhhcchhhhccCCCCCcceecCCC
Confidence            2                   478888864332 2222222 2 5799998876544321100   000111223333334


Q NP_000836.2     202 QAQAMVDIVTAL--GWNYVSTLASEGNYG-ESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAV  278 (908)
Q Consensus       202 ~~~~~~~~l~~~--~~~~v~ii~~~~~~~-~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~vi  278 (908)
                      .++.+++++.+.  +.+++++++.+..++ ..+.+++++.+++. ++++.... ..   +..+....++++.  .++++|
T Consensus       118 ~~~~~~~~l~~~~~~~~~v~~l~~~~~~~~~~~~~~~~~~~~~~-~~~~~~~~-~~---~~~~~~~~~~~~~--~~~~~i  190 (295)
T 3LFT_B          118 PAQQQVELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKA-GLTVETFA-VP---STNEIASTVTVMT--SKVDAI  190 (295)
T ss_dssp             CHHHHHHHHHHHCTTCCEEEEEEETTCHHHHHHHHHHHHHHHHT-TCEEEEEE-ES---SGGGHHHHHHHHH--TTCSEE
T ss_pred             cHHHHHHHHHHHCCCCcEEEEeecCCCCChHHHHHHHHHHHHHc-CCEEEEEE-eC---CHHHHHHHHHHhc--cCCCEE
Confidence            455666666554  678899998654433 45667777777664 34443211 11   1123444444442  367777


Q NP_000836.2     279 IMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       279 v~~~~~~~~~~~l~~~~~~g  298 (908)
                      ++.. +..+..+++++.+.+
T Consensus       191 ~~~~-~~~~~~~~~~~~~~~  209 (295)
T 3LFT_B          191 WVPI-DNTIASGFPTVVSSN  209 (295)
T ss_dssp             EECS-CHHHHHTHHHHHHHT
T ss_pred             EECC-ChhhhcchhHHHHHH
Confidence            6654 333444555555544


No 299
>3HS3_B Ribose operon repressor; PSI-II, NYSGXRC, 11235h, periplasmic binding; 1.6A {Lactobacillus acidophilus}
Probab=95.74  E-value=0.00012  Score=71.98  Aligned_cols=195  Identities=13%  Similarity=0.113  Sum_probs=106.9  Template_Neff=11.500

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ...+..+||++.|..+.            .+......+++.++++.        |+++.+...+. .++    ....+.+
T Consensus         6 ~~~~~~~Ig~v~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~~~~~~~~~-~~~----~~~~~~i   60 (277)
T 3HS3_B            6 YQKKSKMIGIIIPDLNN------------RFYAQIIDGIQEVIQKE--------GYTALISFSTN-SDV----KKYQNAI   60 (277)
T ss_dssp             --CCCCEEEEEESCSCS------------HHHHHHHHHHHHHHHHT--------TCEEEEEECSS-CCH----HHHHHHH
T ss_pred             ccCCCCeEEEEeCCCCC------------hhHHHHHHHHHHHHHHc--------CCEEEEEecCC-CcH----HHHHHHH
Confidence            34567899999986432            24556777777777664        23343332221 221    1222334


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDS  200 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~  200 (908)
                      ++++.                   .++|++|....+...      ....++|+|..+...+.       +....+..+..
T Consensus        61 ~~l~~-------------------~~~d~ii~~~~~~~~------~~~~~ipvv~~~~~~~~-------~~~~~v~~d~~  108 (277)
T 3HS3_B           61 INFEN-------------------NNVDGIITSAFTIPP------NFHLNTPLVMYDSANIN-------DDIVRIVSNNT  108 (277)
T ss_dssp             HHHHH-------------------TTCSEEEEECCCCCT------TCCCSSCEEEESCCCCC-------SSSEEEEECHH
T ss_pred             HHHHH-------------------CCCCEEEEeCCCCCc------ccccCCCEEEecCCCCC-------CCceEEEeccH
Confidence            43332                   478888865433221      13569999987764321       23455666777


Q NP_000836.2     201 YQAQAMVDIVTALGWNYVSTLASE--GNYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLE-TPNARA  277 (908)
Q Consensus       201 ~~~~~~~~~l~~~~~~~v~ii~~~--~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v  277 (908)
                      ..++.+++++.+. .++++++...  ......+.++|++.+++. ++.+.... ..    .......+.++++ ..++++
T Consensus       109 ~~~~~~~~~l~~~-~~~i~~i~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~-~~----~~~~~~~~~~~l~~~~~~~~  181 (277)
T 3HS3_B          109 KGGKESIKLLSKK-IEKVLIQHWPLSLPTIRERIEAMTAEASKL-KIDYLLEE-TP----ENNPYISAQSALNKSNQFDA  181 (277)
T ss_dssp             HHHHHHHHTSCTT-CCEEEEEESCTTSHHHHHHHHHHHHHHHHT-TCEEEEEE-CC----SSCHHHHHHHHHHTGGGCSE
T ss_pred             HHHHHHHHHHHhc-CceEEEEeCCCCCHHHHHHHHHHHHHHHHC-CCceeecC-CC----CCCHHHHHHHHHhhCCCCCE
Confidence            7777777777553 5788888743  334456777888877765 34432111 11    0111122233322 135777


Q NP_000836.2     278 VIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       278 iv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      |++.. +..+..+++++++.|+.
T Consensus       182 i~~~~-d~~a~~~~~al~~~g~~  203 (277)
T 3HS3_B          182 IITVN-DLYAAEIIKEAKRRNLK  203 (277)
T ss_dssp             EECSS-HHHHHHHHHHHHHTTCC
T ss_pred             EEEcC-HHHHHHHHHHHHHCCCC
Confidence            76663 44566778888887763


No 300
>3JVD_A Transcriptional regulators; STRUCTURAL GENOMICS, PSI-2, SUGAR BINDING; HET: SO4; 2.3A {Corynebacterium glutamicum}
Probab=95.72  E-value=0.00012  Score=74.15  Aligned_cols=192  Identities=13%  Similarity=0.121  Sum_probs=105.9  Template_Neff=11.400

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .+..+||++.|..+.            .++..+..+++.++++.        |+++.  +.+.. ++    +...+.+++
T Consensus        62 ~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~~~--~~~~~-~~----~~~~~~~~~  114 (333)
T 3JVD_A           62 HRSALVGVIVPDLSN------------EYYSESLQTIQQDLKAA--------GYQML--VAEAN-SV----QAQDVVMES  114 (333)
T ss_dssp             --CCEEEEEESCSSS------------HHHHHHHHHHHHHHHHH--------TCEEE--EEECC-SH----HHHHHHHHH
T ss_pred             CCCCEEEEEeCCCCC------------hhHHHHHHHHHHHHHHc--------CCeEE--EEECC-CH----HHHHHHHHH
Confidence            467889999886432            24556667777666553        22332  33322 11    122233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   .++|++|......       .+...++|+|..+...+.       +....+..++...
T Consensus       115 l~~-------------------~~~d~ii~~~~~~-------~~~~~~ipvv~~~~~~~~-------~~~~~v~~d~~~~  161 (333)
T 3JVD_A          115 LIS-------------------IQAAGIIHVPVVG-------SIAPEGIPMVQLTRGELG-------PGFPRVLCDDEAG  161 (333)
T ss_dssp             HHH-------------------HTCSEEEECCCTT-------CCC-CCSCEEEECC-----------CCSCEEEECHHHH
T ss_pred             HHh-------------------cCCCEEEEecccc-------cccCCCCCEEEEcCCCCC-------CCCCEEEeCcHHH
Confidence            332                   4778887643221       356679999987764321       2345666666667


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      +..+++++.+.++++++++....  .....+.++|++.+++. ++.+..... .  .+..+....++.+++..++|++++
T Consensus       162 ~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~-~--~~~~~~~~~~~~~~~~~~~dai~~  237 (333)
T 3JVD_A          162 FFQLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIY-GAEVTFHFG-H--YSVESGEEMAQVVFNNGLPDALIV  237 (333)
T ss_dssp             HHHHHHHHCCSSSCEEEEEESCTTSHHHHHHHHHHHHHHHHT-TCEEEEEEC-C--SSHHHHHHHHHHHHHTCCCSEEEE
T ss_pred             HHHHHHHHHcCCCCcEEEEECCcccchHHHHHHHHHHHHHHc-CCccEEEec-C--CCHHHHHHHHHHHHhCCCCCEEEE
Confidence            77778887655788999887532  44566778888888775 344432100 0  111122334444432235778665


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~  299 (908)
                      .. +..+..+++++++.|+
T Consensus       238 ~~-d~~a~~~~~al~~~g~  255 (333)
T 3JVD_A          238 AS-PRLMAGVMRAFTRLNV  255 (333)
T ss_dssp             CC-HHHHHHHHHHHHHTTC
T ss_pred             CC-HHHHHHHHHHHHHCCC
Confidence            53 5556678888888776


No 301
>3JVD_B Transcriptional regulators; STRUCTURAL GENOMICS, PSI-2, SUGAR BINDING; HET: SO4; 2.3A {Corynebacterium glutamicum}
Probab=95.72  E-value=0.00012  Score=74.15  Aligned_cols=192  Identities=13%  Similarity=0.121  Sum_probs=106.7  Template_Neff=11.400

Q NP_000836.2      43 DGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFVQA  122 (908)
Q Consensus        43 ~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~~~  122 (908)
                      .+..+||++.|..+.            .++..+..+++.++++.        |+++.  +.+.. ++    +...+.+++
T Consensus        62 ~~~~~I~~i~~~~~~------------~~~~~~~~g~~~~~~~~--------g~~~~--~~~~~-~~----~~~~~~~~~  114 (333)
T 3JVD_B           62 HRSALVGVIVPDLSN------------EYYSESLQTIQQDLKAA--------GYQML--VAEAN-SV----QAQDVVMES  114 (333)
T ss_dssp             --CCEEEEEESCTTC------------HHHHTTHHHHHHHHHHT--------TCEEE--EEECC-SH----HHHHHHHHH
T ss_pred             CCCCEEEEEeCCCCC------------hhHHHHHHHHHHHHHHc--------CCeEE--EEECC-CH----HHHHHHHHH
Confidence            467889999886432            24556667777666553        22332  33322 11    122233333


Q NP_000836.2     123 LIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQ  202 (908)
Q Consensus       123 l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~  202 (908)
                      ++.                   .++|++|......       .+...++|+|..+...+.       +....+..++...
T Consensus       115 l~~-------------------~~~d~ii~~~~~~-------~~~~~~ipvv~~~~~~~~-------~~~~~v~~d~~~~  161 (333)
T 3JVD_B          115 LIS-------------------IQAAGIIHVPVVG-------SIAPEGIPMVQLTRGELG-------PGFPRVLCDDEAG  161 (333)
T ss_dssp             HHH-------------------TTCSEEEECCC-----------CCSSSCEEEESSCCCB-------TTBCEEEECHHHH
T ss_pred             HHh-------------------cCCCEEEEecccc-------cccCCCCCEEEEcCCCCC-------CCCCEEEeCcHHH
Confidence            332                   4778887643221       356679999987764321       2345666666667


Q NP_000836.2     203 AQAMVDIVTALGWNYVSTLASEG--NYGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIM  280 (908)
Q Consensus       203 ~~~~~~~l~~~~~~~v~ii~~~~--~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~  280 (908)
                      +..+++++.+.++++++++....  .....+.++|++.+++. ++.+..... .  .+..+....++.+++..++|++++
T Consensus       162 ~~~~~~~l~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~-~--~~~~~~~~~~~~~~~~~~~dai~~  237 (333)
T 3JVD_B          162 FFQLTESVLGGSGMNIAALVGEESLSTTQERMRGISHAASIY-GAEVTFHFG-H--YSVESGEEMAQVVFNNGLPDALIV  237 (333)
T ss_dssp             HHHHHHHHCCSSSCEEEEEESCTTSHHHHHHHHHHHHHHHHT-TCEEEEEEC-C--SSHHHHHHHHHHHHHTCCCSEEEE
T ss_pred             HHHHHHHHHcCCCCcEEEEECCcccchHHHHHHHHHHHHHHc-CCccEEEec-C--CCHHHHHHHHHHHHhCCCCCEEEE
Confidence            77778887655788999887532  44566778888888775 344432100 0  111122334444432235778665


Q NP_000836.2     281 FANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       281 ~~~~~~~~~~l~~~~~~g~  299 (908)
                      .. +..+..+++++++.|+
T Consensus       238 ~~-d~~a~~~~~al~~~g~  255 (333)
T 3JVD_B          238 AS-PRLMAGVMRAFTRLNV  255 (333)
T ss_dssp             CC-HHHHHHHHHHHHHTTC
T ss_pred             CC-HHHHHHHHHHHHHCCC
Confidence            53 5556678888888776


No 302
>3S99_A Basic membrane lipoprotein; SSGCID, Basic membrane lipoprotein, Structural; HET: IOD, ADE; 2.05A {Brucella melitensis biovar Abortus}
Probab=95.68  E-value=0.00014  Score=74.71  Aligned_cols=216  Identities=7%  Similarity=-0.005  Sum_probs=102.9  Template_Neff=10.300

Q NP_000836.2      27 MMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTC  106 (908)
Q Consensus        27 ~~~~~~~~~~~~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~  106 (908)
                      ||...+ ...+......+..+||++.|.....          ..+......+++.++++.        |+.+++.+.+..
T Consensus         9 ~~~~~~-~~~~~~~~~~~~~~I~~v~~~~~~d----------~~~~~~~~~g~~~~~~~~--------g~~v~~~~~~~~   69 (356)
T 3S99_A            9 MGTLEA-QTQGPGSMAEEKLKVGFIYIGPPGD----------FGWTYQHDQARKELVEAL--------GDKVETTFLENV   69 (356)
T ss_dssp             ------------------CEEEEEECSSCGGG----------SSHHHHHHHHHHHHHHHH--------TTTEEEEEECSC
T ss_pred             cccccc-cCCCCCCccccccEEEEEEccCCCc----------cchHHHHHHHHHHHHHHH--------CCCeEEEEEecC
Confidence            444333 3334446667889999999753210          024456667777666653        232344444432


Q NP_000836.2     107 SRDTYALEQSLTFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILR-LFKIPQISYASTAPELSD  185 (908)
Q Consensus       107 ~~~~~a~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~-~~~iP~Is~~~~~~~l~~  185 (908)
                      .+.    ....+.+++++.                   .++|+||+...... ..+..+++ ..++|++..+...+    
T Consensus        70 ~~~----~~~~~~i~~~~~-------------------~~~d~II~~~~~~~-~~~~~~~~~~~~ip~v~~~~~~~----  121 (356)
T 3S99_A           70 AEG----ADAERSIKRIAR-------------------AGNKLIFTTSFGYM-DPTVKVAKKFPDVKFEHATGYKT----  121 (356)
T ss_dssp             CTT----HHHHHHHHHHHH-------------------TTCSEEEECSGGGH-HHHHHHHTTCTTSEEEEESCCCC----
T ss_pred             CCh----hhHHHHHHHHHH-------------------cCCCEEEEcChhhh-HHHHHHHHHCCCCEEEEccCCCC----
Confidence            221    122233333332                   57888886543322 22223333 36899888765332    


Q NP_000836.2     186 NTRYDFFSRVVPPDSYQAQAMVDIVTA-LGWNYVSTLASEG-NYGESGVEAFTQISREIG-GVCIAQSQKIPREP-RPGE  261 (908)
Q Consensus       186 ~~~~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v~ii~~~~-~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~-~~~~  261 (908)
                         .+++..+..+....+..++.++.. .+.++|+++.... .....+.++|.+.+++.+ .+.+...  +..+. +...
T Consensus       122 ---~~n~~~v~~d~~~~~~~ag~~~~~~~~~~~i~~i~~~~~~~~~~~~~gf~~~~~~~~~~~~~~~~--~~~~~~d~~~  196 (356)
T 3S99_A          122 ---ADNMSAYNARFYEGRYVQGVIAAKMSKKGIAGYIGSVPVPEVVQGINSFMLGAQSVNPDFRVKVI--WVNSWFDPGK  196 (356)
T ss_dssp             ---BTTEEEEEECHHHHHHHHHHHHHHHCSSCEEEEEECCCCHHHHHHHHHHHHHHHTTCTTCEEEEE--ECSSSCCHHH
T ss_pred             ---CCCeEEEeeehHHHHHHHHHHHHHHcCCCeeEEEeCCCChHHhhhHHHHHHHHHHhCCCCEEEEE--EcCCCCChhH
Confidence               134455556655566666665543 4667899887432 334566777777776532 1222111  11001 1112


Q NP_000836.2     262 FEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       262 ~~~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g  298 (908)
                      ..+.+++++. .++|+|+...+   +..+++++++.+
T Consensus       197 ~~~~~~~ll~-~~~d~I~~~~~---a~~v~~a~~~~g  229 (356)
T 3S99_A          197 EADAAKALID-QGVDIITQHTD---STAAIQVAHDRG  229 (356)
T ss_dssp             HHHHHHHHHH-TTCSEEEESSS---SSHHHHHHHHTT
T ss_pred             HHHHHHHHHH-CCCCEEEeCCC---CHHHHHHHHHcC
Confidence            2344555553 47888877653   456777776654


No 303
>6DSP_B Autoinducer 2-binding protein LsrB; AI-2 receptor, SIGNALING PROTEIN; HET: PAV; 1.37A {Clostridium saccharobutylicum DSM 13864}
Probab=95.34  E-value=0.00028  Score=71.90  Aligned_cols=221  Identities=6%  Similarity=-0.041  Sum_probs=98.5  Template_Neff=11.100

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ......+..+||++.+....            .+...+..+++.++++.        |+++.+.. +...++    ....
T Consensus        14 ~~~~~~~~~~Igvi~~~~~~------------~~~~~~~~g~~~~a~~~--------g~~~~~~~-~~~~~~----~~~~   68 (347)
T 6DSP_B           14 TNSSKKGNVTVTFIPKLTGN------------AFFESANKGAQKYSEQW--------GFKVDYEG-DANASA----ASQV   68 (347)
T ss_dssp             --------CEEEEECSCSSS------------HHHHHHHHHHHHHHHHH--------TCEEEECC-CSSCCH----HHHH
T ss_pred             cCccCCCCeEEEEEecCCCC------------HHHHHHHHHHHHHHHHH--------CCEEEEEc-CCCCCH----HHHH
Confidence            34566778999999875332            24456667777666653        23333321 222221    1222


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +.+++++.                   +++|++|....... .......+...++|+|.++...+.     .....+.+.
T Consensus        69 ~~~~~l~~-------------------~~~d~ii~~~~~~~~~~~~~~~~~~~~ipvv~~~~~~~~-----~~~~~~~v~  124 (347)
T 6DSP_B           69 SVINKAVQ-------------------QGTNAICLSSVDAAGVKDALKAAADAGVTVTTWDSDVDP-----SVRKVMVSQ  124 (347)
T ss_dssp             HHHHHHHH-------------------TTCSEEEECCSCHHHHHHHHHHHHHTTCEEEEESSCCCG-----GGCSEEEES
T ss_pred             HHHHHHHH-------------------cCCCEEEEeCCChHHHHHHHHHHHHCCCEEEEECCCCCc-----ccceeEEee
Confidence            33443332                   47888776433222 223445566789999988754321     011233444


Q NP_000836.2     197 PPDSYQAQAMVDIVTALGWN------YVST--LAS-EG-N---YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFE  263 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~~~~~------~v~i--i~~-~~-~---~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~  263 (908)
                      .++...++.+++++.+.+.+      ++++  +.. .. .   ....+...++...++..++.+.....+....+..+..
T Consensus       125 ~d~~~~g~~~~~~l~~~~~~~~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~  204 (347)
T 6DSP_B          125 GTPEQLGQMLVQMGYDSLKERGKDPEKDAIKYCWHYSNATVTDQNSWQVEGEKYIKSKYPNWQNVAPDNYYSNQDAEQAI  204 (347)
T ss_dssp             CCHHHHHHHHHHHHHHHHHHTTCCTTTSCCEEEEEESCSSCHHHHHHHHHHHHHHHHHCTTCEESCTTCEECTTCHHHHH
T ss_pred             CCHHHHHHHHHHHHHHHHHhcCCCcccccceEEEEecCCCcchHHHHHHHHHHHHHHHCCCcEEccCCCCCCCCCHHHHH
Confidence            55666677777776443322      3333  221 11 1   1112333343333322123322111001001112233


Q NP_000836.2     264 KIIKRLLET-PNARAVIMFANEDDIRRILEAAKKLNQS-GHFLWIGS  308 (908)
Q Consensus       264 ~~~~~l~~~-~~~~viv~~~~~~~~~~~l~~~~~~g~~-~~~~~i~~  308 (908)
                      ..++++++. .++++|++. ++..+..+++++++.|+. .++.+++.
T Consensus       205 ~~~~~~l~~~~~~dai~~~-~d~~a~~~~~al~~~g~~p~~v~v~g~  250 (347)
T 6DSP_B          205 SVGESILSAHSDIDLIICN-DSTALPGQAQAAQNKGLTAKNVTITGF  250 (347)
T ss_dssp             HHHHHHHHHCTTCCEEEEC-STTHHHHHHHHHHHTTCCTTTCEEEEB
T ss_pred             HHHHHHHHHCCCcCEEEEc-CCCchHHHHHHHHHCCCCCCCeEEEeC
Confidence            445555431 246777663 444556778888887764 23444443


No 304
>2FQW_A Membrane lipoprotein tmpC; ABC transport system, ligand-binding protein; HET: NOS; 1.71A {Treponema pallidum}
Probab=95.31  E-value=0.0003  Score=70.64  Aligned_cols=146  Identities=10%  Similarity=0.046  Sum_probs=74.4  Template_Neff=11.200

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANIL-RLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAM----VDIVTALGWNYVS  219 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~-~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~----~~~l~~~~~~~v~  219 (908)
                      +++++||+...... .....++ +..++|++..+...+.      .+++..+..+....+..+    ++++.+.+.++++
T Consensus        61 ~~~d~Ii~~~~~~~-~~~~~~~~~~~~i~~v~~~~~~~~------~~~~~~v~~~~~~~~~~~g~~a~~~~~~~g~~~i~  133 (318)
T 2FQW_A           61 ENMGLVVACGSFLV-EAVIETSARFPKQKFLVIDAVVQD------RDNVVSAVFGQNEGSFLVGVAAALKAKEAGKSAVG  133 (318)
T ss_dssp             TTCSEEEEESGGGH-HHHHHHHHHCTTSCEEEESSCCCS------CTTEEEEEECHHHHHHHHHHHHHHHHHHTTCCEEE
T ss_pred             CCCCEEEEcCHHHH-HHHHHHHHHCCCCeEEEEeccCCC------cccEEEEeechhHHHHHHHHHHHHHHHHcCCCEEE
Confidence            47888886543322 1222222 3458998887654321      122333334433333333    4455445678999


Q NP_000836.2     220 TLASEG-NYGESGVEAFTQISREIGGVCIAQSQKIPREP-RPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKL  297 (908)
Q Consensus       220 ii~~~~-~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~  297 (908)
                      ++.... .....+.++|++.+++.+ ..+.....+..+. +.....+.++++.. .++|+|+... +..+..+++++++.
T Consensus       134 ~i~~~~~~~~~~~~~gf~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~d~i~~~~-~~~~~~~~~a~~~~  210 (318)
T 2FQW_A          134 FIVGMELGMMPLFEAGFEAGVKAVD-PDIQVVVEVANTFSDPQKGQALAAKLYD-SGVNVIFQVA-GGTGNGVIKEARDR  210 (318)
T ss_dssp             EEESCCSTTTHHHHHHHHHHHHHHC-TTCEEEEEECSCSSCHHHHHHHHHHHHH-TTCCEEEEEC-GGGHHHHHHHHHHH
T ss_pred             EEecccCcchhHHHHHHHHHHHHHC-CCCEEEEEEcCCCCCHHHHHHHHHHHHH-cCCCEEEEcC-cHHhHHHHHHHHHh
Confidence            998432 344556677777776532 2211111111001 11123344555553 4788887764 33455677888777


Q NP_000836.2     298 NQS  300 (908)
Q Consensus       298 g~~  300 (908)
                      |+.
T Consensus       211 g~~  213 (318)
T 2FQW_A          211 RLN  213 (318)
T ss_dssp             HHT
T ss_pred             hcC
Confidence            653


No 305
>2FQX_A Membrane lipoprotein tmpC; ABC transport system, ligand-binding protein; HET: GMP; 1.7A {Treponema pallidum}
Probab=95.31  E-value=0.0003  Score=70.64  Aligned_cols=146  Identities=10%  Similarity=0.046  Sum_probs=74.4  Template_Neff=11.200

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANIL-RLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAM----VDIVTALGWNYVS  219 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~-~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~----~~~l~~~~~~~v~  219 (908)
                      +++++||+...... .....++ +..++|++..+...+.      .+++..+..+....+..+    ++++.+.+.++++
T Consensus        61 ~~~d~Ii~~~~~~~-~~~~~~~~~~~~i~~v~~~~~~~~------~~~~~~v~~~~~~~~~~~g~~a~~~~~~~g~~~i~  133 (318)
T 2FQX_A           61 ENMGLVVACGSFLV-EAVIETSARFPKQKFLVIDAVVQD------RDNVVSAVFGQNEGSFLVGVAAALKAKEAGKSAVG  133 (318)
T ss_dssp             TTCSEEEEESTTTH-HHHHHHHHHCTTSCEEEESSCCCS------CTTEEEEEECHHHHHHHHHHHHHHHHHHTTCCEEE
T ss_pred             CCCCEEEEcCHHHH-HHHHHHHHHCCCCeEEEEeccCCC------cccEEEEeechhHHHHHHHHHHHHHHHHcCCCEEE
Confidence            47888886543322 1222222 3458998887654321      122333334433333333    4455445678999


Q NP_000836.2     220 TLASEG-NYGESGVEAFTQISREIGGVCIAQSQKIPREP-RPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKL  297 (908)
Q Consensus       220 ii~~~~-~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~  297 (908)
                      ++.... .....+.++|++.+++.+ ..+.....+..+. +.....+.++++.. .++|+|+... +..+..+++++++.
T Consensus       134 ~i~~~~~~~~~~~~~gf~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~d~i~~~~-~~~~~~~~~a~~~~  210 (318)
T 2FQX_A          134 FIVGMELGMMPLFEAGFEAGVKAVD-PDIQVVVEVANTFSDPQKGQALAAKLYD-SGVNVIFQVA-GGTGNGVIKEARDR  210 (318)
T ss_dssp             EEESCCSTTTHHHHHHHHHHHHHHC-TTCEEEEEECSCSSCHHHHHHHHHHHHH-TTCCEEEEEC-GGGHHHHHHHHHHH
T ss_pred             EEecccCcchhHHHHHHHHHHHHHC-CCCEEEEEEcCCCCCHHHHHHHHHHHHH-cCCCEEEEcC-cHHhHHHHHHHHHh
Confidence            998432 344556677777776532 2211111111001 11123344555553 4788887764 33455677888777


Q NP_000836.2     298 NQS  300 (908)
Q Consensus       298 g~~  300 (908)
                      |+.
T Consensus       211 g~~  213 (318)
T 2FQX_A          211 RLN  213 (318)
T ss_dssp             HHT
T ss_pred             hcC
Confidence            653


No 306
>2FQY_A Membrane lipoprotein tmpC; ABC receptor protein, nucleoside binding; HET: ADN; 1.9A {Treponema pallidum}
Probab=95.31  E-value=0.0003  Score=70.64  Aligned_cols=146  Identities=10%  Similarity=0.046  Sum_probs=74.4  Template_Neff=11.200

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANIL-RLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAM----VDIVTALGWNYVS  219 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~-~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~----~~~l~~~~~~~v~  219 (908)
                      +++++||+...... .....++ +..++|++..+...+.      .+++..+..+....+..+    ++++.+.+.++++
T Consensus        61 ~~~d~Ii~~~~~~~-~~~~~~~~~~~~i~~v~~~~~~~~------~~~~~~v~~~~~~~~~~~g~~a~~~~~~~g~~~i~  133 (318)
T 2FQY_A           61 ENMGLVVACGSFLV-EAVIETSARFPKQKFLVIDAVVQD------RDNVVSAVFGQNEGSFLVGVAAALKAKEAGKSAVG  133 (318)
T ss_dssp             TTCSEEEEESGGGH-HHHHHHHHHCTTSCEEEESSCCCS------CTTEEEEEECHHHHHHHHHHHHHHHHHHTTCSEEE
T ss_pred             CCCCEEEEcCHHHH-HHHHHHHHHCCCCeEEEEeccCCC------cccEEEEeechhHHHHHHHHHHHHHHHHcCCCEEE
Confidence            47888886543322 1222222 3458998887654321      122333334433333333    4455445678999


Q NP_000836.2     220 TLASEG-NYGESGVEAFTQISREIGGVCIAQSQKIPREP-RPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKL  297 (908)
Q Consensus       220 ii~~~~-~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~  297 (908)
                      ++.... .....+.++|++.+++.+ ..+.....+..+. +.....+.++++.. .++|+|+... +..+..+++++++.
T Consensus       134 ~i~~~~~~~~~~~~~gf~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~~~d~i~~~~-~~~~~~~~~a~~~~  210 (318)
T 2FQY_A          134 FIVGMELGMMPLFEAGFEAGVKAVD-PDIQVVVEVANTFSDPQKGQALAAKLYD-SGVNVIFQVA-GGTGNGVIKEARDR  210 (318)
T ss_dssp             EEESCCSTTTHHHHHHHHHHHHHHC-TTCEEEEEECSCSSCHHHHHHHHHHHHH-TTCCEEEEEC-HHHHHHHHHHHHHH
T ss_pred             EEecccCcchhHHHHHHHHHHHHHC-CCCEEEEEEcCCCCCHHHHHHHHHHHHH-cCCCEEEEcC-cHHhHHHHHHHHHh
Confidence            998432 344556677777776532 2211111111001 11123344555553 4788887764 33455677888777


Q NP_000836.2     298 NQS  300 (908)
Q Consensus       298 g~~  300 (908)
                      |+.
T Consensus       211 g~~  213 (318)
T 2FQY_A          211 RLN  213 (318)
T ss_dssp             HHT
T ss_pred             hcC
Confidence            653


No 307
>3H5T_A Transcriptional regulator, LacI family; Transcriptional regulator, DNA-dependent, Protein Structure; 2.53A {Corynebacterium glutamicum}
Probab=95.00  E-value=0.00053  Score=70.44  Aligned_cols=146  Identities=15%  Similarity=0.125  Sum_probs=82.3  Template_Neff=10.800

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++|++|....... ......+...++|+|..+...+       .+.+..+..++...++.+++++.+.+.++|+++...
T Consensus       127 ~~~dgii~~~~~~~-~~~~~~~~~~~ipvV~~~~~~~-------~~~~~~v~~d~~~~g~~~~~~l~~~g~~~i~~i~~~  198 (366)
T 3H5T_A          127 AAVDGVVIYSVAKG-DPHIDAIRARGLPAVIADQPAR-------EEGMPFIAPNNRKAIAPAAQALIDAGHRKIGILSIR  198 (366)
T ss_dssp             CCCSCEEEESCCTT-CHHHHHHHHHTCCEEEESSCCS-------CTTCCEEEECHHHHTHHHHHHHHHTTCCSEEEEEEC
T ss_pred             CCCCEEEEEccCCC-ChHHHHHHHcCCCEEEeCCCcc-------cCCCCEEecChHHHHHHHHHHHHHCCCCcEEEEeCC
Confidence            47787775433322 2333455667999998875432       123445556667778888888876688899998743


Q NP_000836.2     225 G-------------------NYGESGVEAFTQISREIGGVCIAQSQKIPRE-PRPGEFEKIIKRLLE-TPNARAVIMFAN  283 (908)
Q Consensus       225 ~-------------------~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~-~~~~~~~~~~~~l~~-~~~~~viv~~~~  283 (908)
                      .                   .....+.+++.+.+++. ++.+......... .+..+....++++++ ..++++|++.. 
T Consensus       199 ~~~~~~~~~~~~~~~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~ai~~~~-  276 (366)
T 3H5T_A          199 LDRANNDGEVTRERLENAQYQVQRDRVRGAMEVFIEA-GIDPGTVPIMECWINNRQHNFEVAKELLETHPDLTAVLCTV-  276 (366)
T ss_dssp             CSSSCCCEECCHHHHHTCCCTTHHHHHHHHHHHHHHH-TCCGGGSCEEEESSCCHHHHHHHHHHHHHHCTTCCEEEESS-
T ss_pred             ccccCCCCccchHHHHhhchHHHHHHHHHHHHHHHHC-CCCCCCCccccccccchhhHHHHHHHHHHhCCCccEEEECC-
Confidence            2                   23445667777777664 3433211111000 011123334444442 12467776654 


Q NP_000836.2     284 EDDIRRILEAAKKLNQS  300 (908)
Q Consensus       284 ~~~~~~~l~~~~~~g~~  300 (908)
                      +..+..+++++.+.|+.
T Consensus       277 d~~a~~~~~al~~~g~~  293 (366)
T 3H5T_A          277 DALAFGVLEYLKSVGKS  293 (366)
T ss_dssp             HHHHHHHHHHHHHTTCC
T ss_pred             HHHHHHHHHHHHHcCCC
Confidence            44566777888777764


No 308
>6NDI_A Hypothetical Protein CD630_05490; Structural Genomics, Center for Structural; HET: MSE; 2.6A {Klebsiella pneumoniae subsp. pneumoniae}
Probab=94.87  E-value=0.00064  Score=68.56  Aligned_cols=144  Identities=12%  Similarity=0.080  Sum_probs=79.7  Template_Neff=11.600

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++|++|...........  ..+..++|+|..+...+       .+....+..++...++.+++++.+.+.++++++...
T Consensus       119 ~~~d~ii~~~~~~~~~~~--~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~~g~~~~~~l~~~g~~~i~~i~~~  189 (334)
T 6NDI_A          119 HRPDGIIFTTMGLRQVPL--PEKLLTLPCVLANCESL-------SQPVASYIPDDEQGQYDAVKALLAAGYRRPLCLHLP  189 (334)
T ss_dssp             TCCSEEEEEEEEEECCCS--CGGGSSSCSEEEEECCS-------SSCCEEEEECHHHHHHHHHHHHHHTTCCCEEEEECC
T ss_pred             cCCCEEEEeCCCCCCCCC--chHHcCCCEEEEcCCcc-------CCCceEEEcCCHHHHHHHHHHHHHCCCCcEEEEeCC
Confidence            478877764332222221  22347999988765432       123455666777778888888766788899998843


Q NP_000836.2     225 G--NYGESGVEAFTQISREIGGVCIAQSQ--KIP-REPRPG-EFEKIIKRLLE-TPNARAVIMFANEDDIRRILEAAKKL  297 (908)
Q Consensus       225 ~--~~~~~~~~~~~~~~~~~~~i~v~~~~--~~~-~~~~~~-~~~~~~~~l~~-~~~~~viv~~~~~~~~~~~l~~~~~~  297 (908)
                      .  .....+.++|++.+++. ++.+....  ... .+.... ......+.+++ ..++++|++.. +..+..+++++++.
T Consensus       190 ~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~ai~~~~-d~~a~~~~~~l~~~  267 (334)
T 6NDI_A          190 ASQPATIRRRRGLERACREA-GIEPDHLSHSYMGQGDEHYHDIPAVVLAHIREGKPGFDSVICGN-DRIAFMVYQTLLGQ  267 (334)
T ss_dssp             TTSHHHHHHHHHHHHHHHHT-TCCGGGSCEEECCSSGGGGGGHHHHHHHTEETTEESCSEEEESS-HHHHHHHHHHHHHT
T ss_pred             CCChHHHHHHHHHHHHHHHc-CCCcccccccccCCCCcccccHHHHHHHHHHhCCCCCcEEEECC-HHHHHHHHHHHHHC
Confidence            2  24556777888887765 34332110  000 000011 11122233322 13567776653 44566788888887


Q NP_000836.2     298 NQ  299 (908)
Q Consensus       298 g~  299 (908)
                      |+
T Consensus       268 g~  269 (334)
T 6NDI_A          268 GL  269 (334)
T ss_dssp             TC
T ss_pred             CC
Confidence            76


No 309
>6NDI_B Hypothetical Protein CD630_05490; Structural Genomics, Center for Structural; HET: MSE; 2.6A {Klebsiella pneumoniae subsp. pneumoniae}
Probab=94.87  E-value=0.00064  Score=68.56  Aligned_cols=144  Identities=12%  Similarity=0.080  Sum_probs=79.7  Template_Neff=11.600

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++|++|...........  ..+..++|+|..+...+       .+....+..++...++.+++++.+.+.++++++...
T Consensus       119 ~~~d~ii~~~~~~~~~~~--~~~~~~ipvv~~~~~~~-------~~~~~~v~~d~~~~g~~~~~~l~~~g~~~i~~i~~~  189 (334)
T 6NDI_B          119 HRPDGIIFTTMGLRQVPL--PEKLLTLPCVLANCESL-------SQPVASYIPDDEQGQYDAVKALLAAGYRRPLCLHLP  189 (334)
T ss_dssp             TCCSEEEEEEEEEECCCS--CGGGSSSCSEEEEECCS-------SSCCEEEEECHHHHHHHHHHHHHHTTCCCEEEEECC
T ss_pred             cCCCEEEEeCCCCCCCCC--chHHcCCCEEEEcCCcc-------CCCceEEEcCCHHHHHHHHHHHHHCCCCcEEEEeCC
Confidence            478877764332222221  22347999988765432       123455666777778888888766788899998843


Q NP_000836.2     225 G--NYGESGVEAFTQISREIGGVCIAQSQ--KIP-REPRPG-EFEKIIKRLLE-TPNARAVIMFANEDDIRRILEAAKKL  297 (908)
Q Consensus       225 ~--~~~~~~~~~~~~~~~~~~~i~v~~~~--~~~-~~~~~~-~~~~~~~~l~~-~~~~~viv~~~~~~~~~~~l~~~~~~  297 (908)
                      .  .....+.++|++.+++. ++.+....  ... .+.... ......+.+++ ..++++|++.. +..+..+++++++.
T Consensus       190 ~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~ai~~~~-d~~a~~~~~~l~~~  267 (334)
T 6NDI_B          190 ASQPATIRRRRGLERACREA-GIEPDHLSHSYMGQGDEHYHDIPAVVLAHIREGKPGFDSVICGN-DRIAFMVYQTLLGQ  267 (334)
T ss_dssp             TTSHHHHHHHHHHHHHHHHT-TCCGGGSCEEECCSSGGGGGGHHHHHHHTEETTEESCSEEEESS-HHHHHHHHHHHHHT
T ss_pred             CCChHHHHHHHHHHHHHHHc-CCCcccccccccCCCCcccccHHHHHHHHHHhCCCCCcEEEECC-HHHHHHHHHHHHHC
Confidence            2  24556777888887765 34332110  000 000011 11122233322 13567776653 44566788888887


Q NP_000836.2     298 NQ  299 (908)
Q Consensus       298 g~  299 (908)
                      |+
T Consensus       268 g~  269 (334)
T 6NDI_B          268 GL  269 (334)
T ss_dssp             TC
T ss_pred             CC
Confidence            76


No 310
>4IIL_A Membrane lipoprotein TpN38(b); periplasmic-binding protein, riboflavin transport, MEMBRANE; HET: EDO, RBF; 1.3A {Treponema pallidum subsp. pallidum}
Probab=94.79  E-value=0.00072  Score=68.72  Aligned_cols=212  Identities=10%  Similarity=0.067  Sum_probs=105.5  Template_Neff=10.600

Q NP_000836.2      40 IRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTF  119 (908)
Q Consensus        40 ~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~  119 (908)
                      ....++.+||++.|.....          ..+......+++.++++.|..+   .++.+  .+.+...+.    +...+.
T Consensus        27 ~~~~~~~~I~~i~~~~~~~----------~~~~~~~~~gi~~~~~~~~~~g---~~~~~--~~~~~~~~~----~~~~~~   87 (346)
T 4IIL_A           27 VQDERAVRIAVFVPGFRHD----------SPVYAMLCDGVERAVTQERATG---RSIGL--DIIEAGPNQ----ALWREK   87 (346)
T ss_dssp             ----CCEEEEEEESSCSTT----------CHHHHHHHHHHHHHHHHHHTTT---CCEEE--EEEECCSCG----GGHHHH
T ss_pred             CCCccCceEEEEeCCCCCC----------ChHHHHHHHHHHHHHHHHHhcc---ccccc--EEEEcCCCH----HHHHHH
Confidence            4456789999999764211          1255677788888888765321   12233  333332121    122333


Q NP_000836.2     120 VQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANIL-RLFKIPQISYASTAPELSDNTRYDFFSRVVPP  198 (908)
Q Consensus       120 ~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~-~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~  198 (908)
                      +++++.                  .+++|+||+...... .....++ ...++|+|..+...+.      .+.+..+..+
T Consensus        88 l~~~~~------------------~~~~d~Ii~~~~~~~-~~~~~~~~~~~~i~~v~~~~~~~~------~~~~~~v~~d  142 (346)
T 4IIL_A           88 LAHLAA------------------EQRYRLIVSSNPALP-HVLEPILRQFPLQRFLVLDAYAPQ------EHSLITFRYN  142 (346)
T ss_dssp             HHHHHH------------------TTCCSEEEEESTTHH-HHHHHHHHHCTTCCEEEESCCCTT------CSSEEEEEEC
T ss_pred             HHHHHH------------------hCCCCEEEEcChhhH-HHHHHHHHHCCCCEEEEEeCCCCC------CCcEEEEEEc
Confidence            333321                  157888886543222 2222232 3568998887654321      1233444455


Q NP_000836.2     199 DSYQAQAMVDIVTA---------LGWNYVSTLASEGN-YGESG-VEAFTQISREIG-GVCIAQSQKIPREP-RPGEFEKI  265 (908)
Q Consensus       199 ~~~~~~~~~~~l~~---------~~~~~v~ii~~~~~-~~~~~-~~~~~~~~~~~~-~i~v~~~~~~~~~~-~~~~~~~~  265 (908)
                      ....+..++.++..         .+.++|+++..... ....+ .++|++.+++.+ .+++...  +..+. +.....+.
T Consensus       143 ~~~~~~~ag~~~~~~~~~~~~~~~g~~~i~~i~~~~~~~~~~r~~~gf~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~  220 (346)
T 4IIL_A          143 QWEQAYLAGHLSALVSASAMRFANADKKIGLIAGQSYPVMTQTIIPAFLAGARAVDPAFEVDVR--VVGNWYDAAKSADL  220 (346)
T ss_dssp             HHHHHHHHHHHHHHHHHSCCTTCCSSCEEEEEESSCCHHCCCCCHHHHHHHHHHHCTTCEEEEE--ECSSSSCHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHhhhHhhhhcCCCEEEEEeCcCCcchhhhHHHHHHHHHHHhCCCCEEEEE--EecCCCCHHHHHHH
Confidence            55455554444422         25678998885432 22233 677777776531 1222111  11001 11223445


Q NP_000836.2     266 IKRLLETPNARAVIMFANEDDIRRILEAAKKLNQ  299 (908)
Q Consensus       266 ~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g~  299 (908)
                      ++++.. .++|+|+... +..+..+++++++.|.
T Consensus       221 ~~~l~~-~~~d~i~~~~-~~~a~gv~~a~~~~gv  252 (346)
T 4IIL_A          221 ARILFH-EGVDVMMPIC-GGANQGVLAAARELGF  252 (346)
T ss_dssp             HHHHHH-HTCCEEEEEC-GGGHHHHHHHCCCCCC
T ss_pred             HHHHHH-CCCCEEEECC-chhhHHHHHHHHHhCC
Confidence            555553 4788887764 4445667777776653


No 311
>6PI6_C Atrazine periplasmic binding protein; SAD phasing, periplasmic binding protein; HET: OKM; 1.65A {Pseudomonas sp. (strain ADP)}
Probab=94.78  E-value=0.00074  Score=68.92  Aligned_cols=206  Identities=6%  Similarity=-0.033  Sum_probs=104.7  Template_Neff=10.200

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ......+..+||+++|.....          ..+......+++.++++.+        +.+.+.+.+...++    ....
T Consensus        17 ~~~~~~~~~~I~~v~~~~~~d----------~~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~~~~~----~~~~   74 (355)
T 6PI6_C           17 RGSHMQEPLKVAFVYAGPVSD----------AGYTYAHDQGRLAMEKNLG--------AKVKSSYVENVPEG----ADAE   74 (355)
T ss_dssp             ------CCEEEEEECSSCGGG----------SSHHHHHHHHHHHHHHHHG--------GGEEEEEECSCCSG----GGHH
T ss_pred             CCCCCCCCeEEEEEEccCCCc----------cchHHHHHHHHHHHHHHhC--------CCcEEEEEecCCCc----ccHH
Confidence            344566789999999864211          1245667777777777653        33443333322221    1222


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRL-FKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~-~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +.+++++.                   .++|+||+...... ..+..++++ .++|+|..+...+       .+++..+.
T Consensus        75 ~~l~~l~~-------------------~~~d~II~~~~~~~-~~~~~~a~~~~~i~~v~~~~~~~-------~~~~~~v~  127 (355)
T 6PI6_C           75 RVIRKLAA-------------------DGNKLIFTTSFGFM-NPTERVAKAFPNVVFEHATGVKL-------AKNLGVYE  127 (355)
T ss_dssp             HHHHHHHH-------------------TTCSEEEECSGGGH-HHHHHHHHHCTTSEEEEETCCCC-------BTTEEEEE
T ss_pred             HHHHHHHH-------------------CCCCEEEEcChhhH-HHHHHHHHHCCCCEEEEcccCCC-------cCCEEEec
Confidence            33333332                   46788876543322 223333433 6899988765432       12344555


Q NP_000836.2     197 PPDSYQAQAMVDIVTA-LGWNYVSTLASE-GNYGESGVEAFTQISREIG-GVCIAQSQKIPREP-RPGEFEKIIKRLLET  272 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~-~~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~  272 (908)
                      .+....+..++.++.. .+.++|+++... ......+.++|.+.+++.+ .+.+...  +.... +.....+.+++++. 
T Consensus       128 ~d~~~~g~~ag~~a~~~~~~~~i~~i~~~~~~~~~~~~~gf~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~ll~-  204 (355)
T 6PI6_C          128 SRQYEGTYLQGVLAAKMTKTGVIGFVGSFPVPEVIRNINAYTLGAQSVNPKIKTKVI--WVSTWYDPAKERQAAETLIA-  204 (355)
T ss_dssp             ECTHHHHHHHHHHHHHHCSSSEEEEEESCCSHHHHHHHHHHHHHHHTTCTTCEEEEE--ECSCSCCHHHHHHHHHHHHH-
T ss_pred             cchHHHHHHHHHHHHHHcCCCcEEEEeCCCchHHHHHHHHHHHHHHHhCCCCEEEEE--EccCCCCHHHHHHHHHHHHH-
Confidence            5665566655555443 356789988743 2344566777877776532 1222111  11001 11122344555553 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g  298 (908)
                      .++|+|+...+   +..+++++++.|
T Consensus       205 ~~~d~I~~~~~---a~gv~~a~~~~g  227 (355)
T 6PI6_C          205 QGADVLTQNTN---SPATLQVAQEKG  227 (355)
T ss_dssp             TTCCEEEESSS---SSHHHHHHHHTT
T ss_pred             CCCCEEEeCCC---CHHHHHHHHHhC
Confidence            47888877653   356677776655


No 312
>6PII_A Atrazine periplasmic binding protein; SAD phasing, periplasmic binding protein; HET: EMC, GUN, PO4; 1.87A {Pseudomonas sp. (strain ADP)}
Probab=94.78  E-value=0.00074  Score=68.92  Aligned_cols=206  Identities=6%  Similarity=-0.033  Sum_probs=106.5  Template_Neff=10.200

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ......+..+||+++|.....          ..+......+++.++++.+        +.+.+.+.+...++    ....
T Consensus        17 ~~~~~~~~~~I~~v~~~~~~d----------~~~~~~~~~g~~~~~~~~g--------~~~~~~~~~~~~~~----~~~~   74 (355)
T 6PII_A           17 RGSHMQEPLKVAFVYAGPVSD----------AGYTYAHDQGRLAMEKNLG--------AKVKSSYVENVPEG----ADAE   74 (355)
T ss_dssp             ---CCCCCEEEEEECSSCGGG----------SSHHHHHHHHHHHHHHHHG--------GGEEEEEECSCCST----HHHH
T ss_pred             CCCCCCCCeEEEEEEccCCCc----------cchHHHHHHHHHHHHHHhC--------CCcEEEEEecCCCc----ccHH
Confidence            344566789999999864211          1245667777777777653        33443333322221    1222


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRL-FKIPQISYASTAPELSDNTRYDFFSRVV  196 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~-~~iP~Is~~~~~~~l~~~~~~~~~~~~~  196 (908)
                      +.+++++.                   .++|+||+...... ..+..++++ .++|+|..+...+       .+++..+.
T Consensus        75 ~~l~~l~~-------------------~~~d~II~~~~~~~-~~~~~~a~~~~~i~~v~~~~~~~-------~~~~~~v~  127 (355)
T 6PII_A           75 RVIRKLAA-------------------DGNKLIFTTSFGFM-NPTERVAKAFPNVVFEHATGVKL-------AKNLGVYE  127 (355)
T ss_dssp             HHHHHHHH-------------------TTCSEEEECSGGGH-HHHHHHHHHCTTSEEEEESCCCC-------BTTEEEEE
T ss_pred             HHHHHHHH-------------------CCCCEEEEcChhhH-HHHHHHHHHCCCCEEEEcccCCC-------cCCEEEec
Confidence            33333332                   46788876543322 223333433 6899988765432       12344555


Q NP_000836.2     197 PPDSYQAQAMVDIVTA-LGWNYVSTLASE-GNYGESGVEAFTQISREIG-GVCIAQSQKIPREP-RPGEFEKIIKRLLET  272 (908)
Q Consensus       197 ~~~~~~~~~~~~~l~~-~~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~  272 (908)
                      .+....+..++.++.. .+.++|+++... ......+.++|.+.+++.+ .+.+...  +.... +.....+.+++++. 
T Consensus       128 ~d~~~~g~~ag~~a~~~~~~~~i~~i~~~~~~~~~~~~~gf~~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~ll~-  204 (355)
T 6PII_A          128 SRQYEGTYLQGVLAAKMTKTGVIGFVGSFPVPEVIRNINAYTLGAQSVNPKIKTKVI--WVSTWYDPAKERQAAETLIA-  204 (355)
T ss_dssp             ECTHHHHHHHHHHHHHHCSSSEEEEEESCCCHHHHHHHHHHHHHHHTTCTTCEEEEE--ECSSSCCHHHHHHHHHHHHH-
T ss_pred             cchHHHHHHHHHHHHHHcCCCcEEEEeCCCchHHHHHHHHHHHHHHHhCCCCEEEEE--EccCCCCHHHHHHHHHHHHH-
Confidence            5665566655555443 356789988743 2344566777877776532 1222111  11001 11122344555553 


Q NP_000836.2     273 PNARAVIMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       273 ~~~~viv~~~~~~~~~~~l~~~~~~g  298 (908)
                      .++|+|+...+   +..+++++++.|
T Consensus       205 ~~~d~I~~~~~---a~gv~~a~~~~g  227 (355)
T 6PII_A          205 QGADVLTQNTN---SPATLQVAQEKG  227 (355)
T ss_dssp             TTCCEEEESSS---SSHHHHHHHHTT
T ss_pred             CCCCEEEeCCC---CHHHHHHHHHhC
Confidence            47888877653   356677776655


No 313
>6RQG_A 46 kDa surface antigen; immunodominant surface protein Mycoplasma hyopneumoniae; 3.1A {Mycoplasma hyopneumoniae J}
Probab=94.68  E-value=0.00085  Score=68.97  Aligned_cols=92  Identities=14%  Similarity=-0.013  Sum_probs=52.0  Template_Neff=8.700

Q NP_000836.2     145 DKISGVIGAAASS-VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTAL----------  213 (908)
Q Consensus       145 ~~v~~vIg~~~s~-~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~----------  213 (908)
                      .++|++|...... ........+...++|+|.++...+..     ......+..++...++.+++++.+.          
T Consensus        76 ~~~dgIIi~~~~~~~~~~~~~~~~~~giPvV~~~~~~~~~-----~~~~~~V~~d~~~~g~~a~~~l~~~~~~~~~~~~~  150 (387)
T 6RQG_A           76 PAPKGFIIAPENGSGVGTAVNTIADKGIPIVAYDRLITGS-----DKYDWYVSFDNEKVGELQGLSLAAGLLGKEDGAFD  150 (387)
T ss_dssp             SCCSCEEECCSSTTTTHHHHHHHHTTTCCEEEESSCCCSC-----CCCCEEEEECHHHHHHHHHHHHHHHHHTCCSSCCS
T ss_pred             cCCCEEEEeCCCcccHHHHHHHHHHCCCCEEEEecCCCCC-----CcccEEEEcCHHHHHHHHHHHHHHHhcCCCCCCcc
Confidence            4678777543322 22233445667899999887643310     1234455566666666666665322          


Q NP_000836.2     214 ---------------GWNYVSTLAS--EGNYGESGVEAFTQISRE  241 (908)
Q Consensus       214 ---------------~~~~v~ii~~--~~~~~~~~~~~~~~~~~~  241 (908)
                                     +.++++++..  .+.....+.++|.+.+++
T Consensus       151 ~~~~~~~~~~~~~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~l~~  195 (387)
T 6RQG_A          151 SIDQMNEYLKSHMPQETISFYTIAGSQDDNNSQYFYNGAMKVLKE  195 (387)
T ss_dssp             SHHHHHHHHHHTCCSSCEEEEECBCCTTSHHHHHHHHHHHHHHHH
T ss_pred             chHHHhHHHHHhCCCCceEEEEEECCCCChhHHHHHHHHHHHHHH
Confidence                           2467777753  223445567777777765


No 314
>6RUX_C Surface antigen P46; immunodominant surface protein Mycoplasma hyopneumoniae; HET: MAL; 2.5A {Mycoplasma hyopneumoniae J}
Probab=94.68  E-value=0.00085  Score=68.97  Aligned_cols=92  Identities=14%  Similarity=-0.013  Sum_probs=52.0  Template_Neff=8.700

Q NP_000836.2     145 DKISGVIGAAASS-VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTAL----------  213 (908)
Q Consensus       145 ~~v~~vIg~~~s~-~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~----------  213 (908)
                      .++|++|...... ........+...++|+|.++...+..     ......+..++...++.+++++.+.          
T Consensus        76 ~~~dgIIi~~~~~~~~~~~~~~~~~~giPvV~~~~~~~~~-----~~~~~~V~~d~~~~g~~a~~~l~~~~~~~~~~~~~  150 (387)
T 6RUX_C           76 PAPKGFIIAPENGSGVGTAVNTIADKGIPIVAYDRLITGS-----DKYDWYVSFDNEKVGELQGLSLAAGLLGKEDGAFD  150 (387)
T ss_dssp             SCCSCEEECCSSTTTTHHHHHHHHTTTCCEEEESSCCCSC-----SCCCEEEEECHHHHHHHHHHHHHHHHTTCCSSCCS
T ss_pred             cCCCEEEEeCCCcccHHHHHHHHHHCCCCEEEEecCCCCC-----CcccEEEEcCHHHHHHHHHHHHHHHhcCCCCCCcc
Confidence            4678777543322 22233445667899999887643310     1234455566666666666665322          


Q NP_000836.2     214 ---------------GWNYVSTLAS--EGNYGESGVEAFTQISRE  241 (908)
Q Consensus       214 ---------------~~~~v~ii~~--~~~~~~~~~~~~~~~~~~  241 (908)
                                     +.++++++..  .+.....+.++|.+.+++
T Consensus       151 ~~~~~~~~~~~~~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~l~~  195 (387)
T 6RUX_C          151 SIDQMNEYLKSHMPQETISFYTIAGSQDDNNSQYFYNGAMKVLKE  195 (387)
T ss_dssp             SHHHHHHHHHHTCCSSCEEEEECBCCTTSHHHHHHHHHHHHHHHH
T ss_pred             chHHHhHHHHHhCCCCceEEEEEECCCCChhHHHHHHHHHHHHHH
Confidence                           2467777753  223445567777777765


No 315
>6S3T_T 46 kDa surface antigen, Immunoglobulin; immunodominant surface protein Mycoplasma hyopneumoniae; HET: XYP; 3.5A {Mycoplasma hyopneumoniae J}
Probab=94.68  E-value=0.00085  Score=68.97  Aligned_cols=92  Identities=14%  Similarity=-0.013  Sum_probs=52.0  Template_Neff=8.700

Q NP_000836.2     145 DKISGVIGAAASS-VSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTAL----------  213 (908)
Q Consensus       145 ~~v~~vIg~~~s~-~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~----------  213 (908)
                      .++|++|...... ........+...++|+|.++...+..     ......+..++...++.+++++.+.          
T Consensus        76 ~~~dgIIi~~~~~~~~~~~~~~~~~~giPvV~~~~~~~~~-----~~~~~~V~~d~~~~g~~a~~~l~~~~~~~~~~~~~  150 (387)
T 6S3T_T           76 PAPKGFIIAPENGSGVGTAVNTIADKGIPIVAYDRLITGS-----DKYDWYVSFDNEKVGELQGLSLAAGLLGKEDGAFD  150 (387)
T ss_dssp             SCCSCEEECCSSTTTTHHHHHHHHHTTCCEEEESSCCCSC-----CCCCEEEEECHHHHHHHHHHHHHHHHTTCCSSCCS
T ss_pred             cCCCEEEEeCCCcccHHHHHHHHHHCCCCEEEEecCCCCC-----CcccEEEEcCHHHHHHHHHHHHHHHhcCCCCCCcc
Confidence            4678777543322 22233445667899999887643310     1234455566666666666665322          


Q NP_000836.2     214 ---------------GWNYVSTLAS--EGNYGESGVEAFTQISRE  241 (908)
Q Consensus       214 ---------------~~~~v~ii~~--~~~~~~~~~~~~~~~~~~  241 (908)
                                     +.++++++..  .+.....+.++|.+.+++
T Consensus       151 ~~~~~~~~~~~~~~~g~~~i~~i~~~~~~~~~~~r~~g~~~~l~~  195 (387)
T 6S3T_T          151 SIDQMNEYLKSHMPQETISFYTIAGSQDDNNSQYFYNGAMKVLKE  195 (387)
T ss_dssp             CHHHHHHHHHHSCCSSCEEEEECBCCTTSTHHHHHHHHHHHHHHH
T ss_pred             chHHHhHHHHHhCCCCceEEEEEECCCCChhHHHHHHHHHHHHHH
Confidence                           2467777753  223445567777777765


No 316
>4FE4_A Xylose operon regulatory protein; dauixie, d-xylose, XylR, DNA looping; 3.45A {Escherichia coli}
Probab=94.62  E-value=0.00092  Score=69.19  Aligned_cols=148  Identities=14%  Similarity=0.103  Sum_probs=82.2  Template_Neff=11.500

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++|++|.+..+   ......++..++|+|..+...+...   ..+....+..++...++.+++++.+.+.++++++...
T Consensus        55 ~~~dgiI~~~~~---~~~~~~~~~~~ipvv~~~~~~~~~~---~~~~~~~v~~d~~~~g~~~~~~l~~~g~~~i~~i~~~  128 (392)
T 4FE4_A           55 WLGDGVIADFDD---KQIEQALADVDVPIVGVGGSYHLAE---SYPPVHYIATDNYALVESAFLHLKEKGVNRFAFYGLP  128 (392)
T ss_dssp             CCCSEEEEETTS---HHHHTTSTTCCSCEEEECBCCSSGG---GCCSSEECEECHHHHHHHHHHHHHHHSCCCEEEECCC
T ss_pred             hcCCEEEEeCCC---HHHHHHHhcCCCCEEEecCCccccC---CCCCCeEEEeCHHHHHHHHHHHHHHcCCCeEEEeCCc
Confidence            467777765322   2233445667999998776432100   1234456667777778888888866678889988753


Q NP_000836.2     225 GN----YGESGVEAFTQISREIGGVCIAQSQKI-PREPRPGEFEKIIKRLLE-TPNARAVIMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       225 ~~----~~~~~~~~~~~~~~~~~~i~v~~~~~~-~~~~~~~~~~~~~~~l~~-~~~~~viv~~~~~~~~~~~l~~~~~~g  298 (908)
                      ..    ....+.++|.+.+++. +......... ....+..+....++++++ ..++|+|++.. +..+..+++++.+.|
T Consensus       129 ~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~ii~~~-d~~a~~~~~al~~~g  206 (392)
T 4FE4_A          129 ESSGKRWATEREYAFRQLVAEE-KYRGVVYQGLETAPENWQHAQNRLADWLQTLPPQTGIIAVT-DARARHILQVCEHLH  206 (392)
T ss_dssp             TTSSCCHHHHHHHHHHHHHTTS-SSCEEEECCCCSSCSSHHHHHHHHHHHHHHSCSSEEEEESS-TTHHHHHHHHHHHTT
T ss_pred             hhhcchHHHHHHHHHHHHHHhh-ccceeecCCCCCCCccHHHHHHHHHHHHHcCCCCcEEEEeC-cHHHHHHHHHHHHcC
Confidence            32    3456677888877654 2221111000 000111122334444432 12467776654 445667778888777


Q NP_000836.2     299 QS  300 (908)
Q Consensus       299 ~~  300 (908)
                      +.
T Consensus       207 ~~  208 (392)
T 4FE4_A          207 IP  208 (392)
T ss_dssp             CC
T ss_pred             CC
Confidence            64


No 317
>4FE7_A Xylose operon regulatory protein; HTH_ARAC, Helix-turn-helix, PBP, periplasmic binding; HET: XYS; 2.9A {Escherichia coli}
Probab=94.42  E-value=0.0012  Score=68.89  Aligned_cols=205  Identities=12%  Similarity=0.051  Sum_probs=108.3  Template_Neff=11.100

Q NP_000836.2      38 HSIRVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSL  117 (908)
Q Consensus        38 ~~~~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~  117 (908)
                      ......+..+||++.|. ..            .+...+..+++.++++.+        +.+.+  .+.. +.    ..  
T Consensus        18 ~~~~~~~~~~I~v~~~~-~~------------~~~~~~~~g~~~~a~~~g--------~~~~~--~~~~-~~----~~--   67 (412)
T 4FE7_A           18 GSHMFTKRHRITLLFNA-NK------------AYDRQVVEGVGEYLQASQ--------SEWDI--FIEE-DF----RA--   67 (412)
T ss_dssp             ---CCCCCEEEEEECCT-TS------------HHHHHHHHHHHHHHHHHT--------CCEEE--EECC--C----C---
T ss_pred             CCCcCCCceEEEEEEeC-Cc------------HHHHHHHHHHHHHHHHcC--------CCcEE--Eeec-ch----Hh--
Confidence            34556678999999986 21            255667778777776643        22222  2221 11    11  


Q NP_000836.2     118 TFVQALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVP  197 (908)
Q Consensus       118 ~~~~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~  197 (908)
                       .++.+..                   ..+|++|.+...   ......+...++|+|..+...+..   ...+....+..
T Consensus        68 -~~~~~~~-------------------~~~dgiI~~~~~---~~~~~~~~~~~ipvv~~~~~~~~~---~~~~~~~~v~~  121 (412)
T 4FE7_A           68 -RIDKIKD-------------------WLGDGVIADFDD---KQIEQALADVDVPIVGVGGSYHLA---ESYPPVHYIAT  121 (412)
T ss_dssp             ---------------------------CCCSEEEEETTC---HHHHHHHTTCCSCEEEEEECCSSG---GGSCSSEEEEE
T ss_pred             -hHHHHHh-------------------hCCCEEEEeCCC---HHHHHHHhcCCCCEEEecCCcccc---CCCCCCcEEEe
Confidence             1222211                   456777765322   223344566799999887643210   01233455667


Q NP_000836.2     198 PDSYQAQAMVDIVTALGWNYVSTLASEG----NYGESGVEAFTQISREIGGVCIAQSQK-IPREPRPGEFEKIIKRLLE-  271 (908)
Q Consensus       198 ~~~~~~~~~~~~l~~~~~~~v~ii~~~~----~~~~~~~~~~~~~~~~~~~i~v~~~~~-~~~~~~~~~~~~~~~~l~~-  271 (908)
                      ++...++.+++++.+.+.++++++....    .....+.++|++.+++. +........ .....+..+....++++++ 
T Consensus       122 d~~~~g~~a~~~l~~~g~~~i~~i~~~~~~~~~~~~~r~~g~~~~~~~~-~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~  200 (412)
T 4FE7_A          122 DNYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEE-KYRGVVYQGLETAPENWQHAQNRLADWLQT  200 (412)
T ss_dssp             CHHHHHHHHHHHHHHTTCCEEEEECCCTTSCCHHHHHHHHHHHHHHTTS-SSCCEEECCSCSSCSSHHHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHcCCCeEEEecCCcccccchHHHHHHHHHHHHhhc-CceeeeecCcccCCccHHHHHHHHHHHHHc
Confidence            7777788888888666778898887432    23556677888877764 232111100 0000111122334444432 


Q NP_000836.2     272 TPNARAVIMFANEDDIRRILEAAKKLNQS  300 (908)
Q Consensus       272 ~~~~~viv~~~~~~~~~~~l~~~~~~g~~  300 (908)
                      ..++++|++.. +..+..+++++.+.|+.
T Consensus       201 ~~~~~~ii~~~-d~~a~~~~~al~~~g~~  228 (412)
T 4FE7_A          201 LPPQTGIIAVT-DARARHILQVCEHLHIP  228 (412)
T ss_dssp             SCTTEEEEESS-HHHHHHHHHHHHHHTCC
T ss_pred             CCCCeEEEEeC-cHHHHHHHHHHHHCCCC
Confidence            12467776653 44556777788777764


No 318
>2HQB_A Transcriptional activator of comK gene; Berkeley Structure Genomics Center Target; 2.7A {Bacillus halodurans}
Probab=93.50  E-value=0.0031  Score=61.96  Aligned_cols=140  Identities=9%  Similarity=-0.001  Sum_probs=72.1  Template_Neff=11.200

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRL-FKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVT-ALGWNYVSTLA  222 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~-~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~-~~~~~~v~ii~  222 (908)
                      .++|+||....... .....+++. .++|+|..+...+       .+.+..+..+....+..++.++. ..+.++|+++.
T Consensus        62 ~~~d~Ii~~~~~~~-~~~~~~a~~~~~i~~v~~~~~~~-------~~~~~~v~~d~~~~~~~a~~~~~~~~~~~~i~~i~  133 (296)
T 2HQB_A           62 GGVNLIFGHGHAFA-EYFSTIHNQYPDVHFVSFNGEVK-------GENITSLHFEGYAMGYFGGMVAASMSETHKVGVIA  133 (296)
T ss_dssp             TTCCEEEECSTHHH-HHHHTTTTSCTTSEEEEESCCCC-------SSSEEEEEECCHHHHHHHHHHHHHTCSSSEEEEEE
T ss_pred             CCCCEEEEeCHHHH-HHHHHHHHHCCCcEEEEecCCcC-------CCCEEEEEechhHHHHHHHHHHHHhcCCCcEEEEe
Confidence            47888876543322 223333332 6899988765432       13344555555556666666654 45678899887


Q NP_000836.2     223 SEGNYGESGVEAFTQISREIGGVCIAQSQKIPREPR-PGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       223 ~~~~~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~-~~~~~~~~~~l~~~~~~~viv~~~~~~~~~~~l~~~~~~g  298 (908)
                      ....  ..+.++|.+.+++.+...+..  .+..... .......++++.. .++|+|+... +..+..+++++++.|
T Consensus       134 ~~~~--~~~~~gf~~~~~~~~~~~~~~--~~~~~~~d~~~~~~~~~~~~~-~~~d~i~~~~-~~~~~~~~~a~~~~g  204 (296)
T 2HQB_A          134 AFPW--QPEVEGFVDGAKYMNESEAFV--RYVGEWTDADKALELFQELQK-EQVDVFYPAG-DGYHVPVVEAIKDQG  204 (296)
T ss_dssp             SCTT--CHHHHHHHHHHHHTTCCEEEE--EECSSSSCHHHHHHHHHHHHT-TTCCEEECCC-TTTHHHHHHHHHHHT
T ss_pred             cCCC--chHHHHHHHHHHHhCCCceEE--EEeCCCCCHHHHHHHHHHHHH-CCCCEEEEcC-CcccHHHHHHHHHcC
Confidence            5432  235667776665432111110  0110011 1122334444443 4678877653 444556677776655


No 319
>6SHU_A Basic membrane protein D; transporter, nucleoside, purine, TRANSPORT PROTEIN; HET: ADN; 1.43002869382A {Borrelia burgdorferi (strain JD1)}
Probab=93.26  E-value=0.0039  Score=63.47  Aligned_cols=205  Identities=10%  Similarity=-0.043  Sum_probs=106.0  Template_Neff=10.300

Q NP_000836.2      41 RVDGDIILGGLFPVHAKGERGVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV  120 (908)
Q Consensus        41 ~~~~~i~Ig~l~p~~~~~~~~~~c~~~~~~~~~~~~~a~~~A~~~iN~~~~il~g~~l~~~~~d~~~~~~~a~~~~~~~~  120 (908)
                      ......+||++.|.....          ..+......+++.+.++.|        +++  ...+.  ++    ....+.+
T Consensus        43 ~~~~~~~I~~i~~~~~~d----------~~~~~~~~~g~~~~~~~~g--------~~~--~~~~~--~~----~~~~~~l   96 (361)
T 6SHU_A           43 GKSEAKTVSLIVDGAFDD----------KGFNESSSKAIRKLKADLN--------INI--IEKAS--TG----NSYLGDI   96 (361)
T ss_dssp             -CCTTCEEEEEEESCSCS----------SSHHHHHHHHHHHHHHHHC--------CEE--EEEEE--CG----GGHHHHH
T ss_pred             CCcCCcEEEEEECCCCCC----------CchHHHHHHHHHHHHHHhC--------CeE--EEcCC--Cc----cchHHHH
Confidence            445678999999853211          1245567777777776653        222  22221  11    1222333


Q NP_000836.2     121 QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRL-FKIPQISYASTAPELSDNTRYDFFSRVVPPD  199 (908)
Q Consensus       121 ~~l~~~~~~~~~~~~~~~~~~~~~~~v~~vIg~~~s~~~~~va~~~~~-~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~  199 (908)
                      +++..                   .++|+||+..... ...+..+++. .++|++.++...+...   ..+++..+..+.
T Consensus        97 ~~l~~-------------------~~~d~II~~~~~~-~~~~~~~a~~~~~i~~v~~~~~~~~~~---~~~~~~~v~~d~  153 (361)
T 6SHU_A           97 ANLED-------------------GNSNLIWGIGFRL-SDILFQRASENVSVNYAIIEGVYDEIQ---IPKNLLNISFRS  153 (361)
T ss_dssp             HHHHH-------------------TTCSEEEEESGGG-HHHHHHHHHHCTTSCEEEESCCCSSCC---CCTTEEEEEECH
T ss_pred             HHHHh-------------------CCCCEEEEeChhh-HHHHHHHHHhCCCCcEEEeecCCcccc---CcCCEEEEEeCH
Confidence            43332                   4788888653322 2223333332 6899888776432100   123455566666


Q NP_000836.2     200 SYQAQAMVDIVTA-LGWNYVSTLASE-GNYGESGVEAFTQISREIG-GVCIAQSQKIPREP-RPGEFEKIIKRLLETPNA  275 (908)
Q Consensus       200 ~~~~~~~~~~l~~-~~~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~~~~  275 (908)
                      ...+..++.++.. .+.++|+++... ......+.++|.+.+++.+ .+.+...  +..+. +.....+.++++.. .++
T Consensus       154 ~~~~~lag~~~~~~~~~~~ig~i~~~~~~~~~~~~~gf~~~~~~~~~~~~~~~~--~~~~~~d~~~a~~~~~~~~~-~~~  230 (361)
T 6SHU_A          154 EEVAFLAGYFASKASKTGKIGFVGGVRGKVLESFMYGYEAGAKYANSNIKVVSQ--YVGTFGDFGLGRSTASNMYR-DGV  230 (361)
T ss_dssp             HHHHHHHHHHHHHHCSSSEEEEEESSCSHHHHHHHHHHHHHHHHHCTTCEEEEE--ECSSSSCHHHHHHHHHHHHH-TTC
T ss_pred             HHHHHHHHHHHHHHcCCCeEEEEeCCCChHHHHHHHHHHHHHHHHCcCCEEEEE--ECCCCCChHHHHHHHHHHHH-cCC
Confidence            6666666666544 456789998743 2344556677777765532 1222111  11001 11123344555553 478


Q NP_000836.2     276 RAVIMFANEDDIRRILEAAKKLN  298 (908)
Q Consensus       276 ~viv~~~~~~~~~~~l~~~~~~g  298 (908)
                      |+|+... +..+..+++++++.|
T Consensus       231 d~I~~~~-~~~~~g~~~a~~~~g  252 (361)
T 6SHU_A          231 DIIFAAA-GLSGIGVIEAAKELG  252 (361)
T ss_dssp             CEEEEES-THHHHHHHHHHHHHC
T ss_pred             CEEEECC-chHHHHHHHHHHHHC
Confidence            8887764 345566777777765


No 320
>4P98_A Basic membrane lipoprotein; Structural Genomics, PSI-Biology, Midwest Center; HET: MLY, MLZ, BR; 1.9A {Conexibacter woesei}
Probab=91.79  E-value=0.01  Score=58.80  Aligned_cols=133  Identities=5%  Similarity=-0.089  Sum_probs=64.4  Template_Neff=11.000

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILR-LFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTA-LGWNYVSTLA  222 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~-~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~-~~~~~v~ii~  222 (908)
                      +++|+||+...... .....+.+ ..++|++..+...+...   ..+++..+..+....+..+..++.. .+.++|+++.
T Consensus        74 ~~~d~Ii~~~~~~~-~~~~~~~~~~~~i~~v~~~~~~~~~~---~~~~~~~v~~~~~~~~~~ag~~~~~~~~~~~i~~i~  149 (317)
T 4P98_A           74 RGFDLVVGHGIDVS-EPILRVATEFPDVHFSASGDATLAER---LPPNVDGWTYDFGQLGYLDGFVAGSLRGVEKVGAVG  149 (317)
T ss_dssp             TTCSEEEEESHHHH-HHHHHHHTTCTTSEEEEECCGGGGGG---CCTTEEEEEECHHHHHHHHHHHHHTSSSCCEEEEEE
T ss_pred             CCCCEEEEeCHHhH-HHHHHHHHHCCCCEEEEccCcchhcc---CCCCeEEEEeehHHHHHHHHHHHHHHcCCCcEEEEe
Confidence            57888886543321 22222222 35899887665332100   0234444555555455555544432 3567899987


Q NP_000836.2     223 SE-GNYGESGVEAFTQISREIG-GVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFAN  283 (908)
Q Consensus       223 ~~-~~~~~~~~~~~~~~~~~~~-~i~v~~~~~~~~~~~~~~~~~~~~~l~~~~~~~viv~~~~  283 (908)
                      .. ......+.++|.+.+++.+ .+.+........ .+.....+.++++++ .++|+|+...+
T Consensus       150 ~~~~~~~~~~~~gf~~~~~~~~~~~~~~~~~~~~~-~d~~~~~~~~~~l~~-~~~d~i~~~~~  210 (317)
T 4P98_A          150 GPQLPFVLATHKGIRAGLKAANPRASYEETYTGRF-YDLQKEQEAARGLLD-KGAQLLVATDD  210 (317)
T ss_dssp             SSCCHHHHHHHHHHHHHHHHHCTTCEEEEEECSSS-SCHHHHHHHHHHHHH-TTCSSEEESSC
T ss_pred             CCCChHHHHHHHHHHHHHHHHCCCCEEEEEEccCC-CCHHHHHHHHHHHHH-CCCCEEEECCC
Confidence            43 2234456677777776531 122221110000 011223345555553 47888777643


No 321
>4PEV_C solute binding protein; Structural Genomics, PSI-Biology, Midwest Center; HET: ADN, MSE; 2.58A {Aeropyrum pernix}
Probab=90.15  E-value=0.022  Score=58.94  Aligned_cols=145  Identities=11%  Similarity=-0.042  Sum_probs=70.8  Template_Neff=9.100

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANIL-RLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAM----VDIVTA-----LG  214 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~-~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~----~~~l~~-----~~  214 (908)
                      .++|+||....... .....++ ...++|++..+...+.     ..+++..+..+....+..+    +.++.+     .+
T Consensus       110 ~g~D~II~~~~~~~-~~~~~~a~~~~~i~fv~~~~~~~~-----~~~nv~~v~~d~~~~g~laG~~aa~~~~~~~~~~~g  183 (422)
T 4PEV_C          110 GEYDLIVLVGFLWQ-EPLEKVAPRYPEQKYALIDAATRE-----RYDNVASYLFREQEVASLVGIIAADIANNISKATGE  183 (422)
T ss_dssp             CCCSEEEEESGGGH-HHHHHHHHHCTTSEEEEESBCCSS-----CCTTEEEEEECHHHHHHHHHHHHHHHHHHHHHHHSS
T ss_pred             CCCCEEEEeCcccH-HHHHHHHHHCCCCeEEEEeCCCcc-----CCCCEEEEEECHHHHHHHHHHHHHHHHhhHhhhhCC
Confidence            47888886543322 1122222 2468998877654321     0123334444444433333    333321     24


Q NP_000836.2     215 WNYVSTLASE-GNYGESGVEAFTQISREIG-----GVCIAQSQKIPREP-RPGEFEKIIKRLLETPNARAVIMFANEDDI  287 (908)
Q Consensus       215 ~~~v~ii~~~-~~~~~~~~~~~~~~~~~~~-----~i~v~~~~~~~~~~-~~~~~~~~~~~l~~~~~~~viv~~~~~~~~  287 (908)
                      .++|++|... ......+.++|.+.+++.+     .+.+...  +.... +.......++++.. .++|+|+... +...
T Consensus       184 ~~~Ig~i~g~~~~~~~~~~~gf~~g~~~~~~~~~~~~~v~~~--~~~~~~d~~~a~~~a~~ll~-~g~dvI~~~~-~~~a  259 (422)
T 4PEV_C          184 EAKAGAVAGMDIPPLWRFHIGYLYGVQYYNQAMGTDVEMVWT--YTGRFDDPTLGKTTAEQMLQ-QGVRVFYGVA-GLTH  259 (422)
T ss_dssp             CCEEEEEECCCSHHHHHHHHHHHHHHHHHHHTTTCCCCEEEE--ECSCSSCHHHHHHHHHHHHH-TTEEEEEEES-TTHH
T ss_pred             CCEEEEEECCCChHHHHHHHHHHHHHHHHCHhcCCCCEEEEE--EecCCCChHHHHHHHHHHHH-CCCCEEEEcc-chhh
Confidence            6789888743 2334456667777665531     1122111  11001 11122344555553 4788877664 4445


Q NP_000836.2     288 RRILEAAKKLNQ  299 (908)
Q Consensus       288 ~~~l~~~~~~g~  299 (908)
                      ..+++++++.++
T Consensus       260 ~gv~~a~~~~g~  271 (422)
T 4PEV_C          260 VGMFNAVKEAAA  271 (422)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHH
Confidence            667777777765


No 322
>5ER3_A Sugar ABC transporter, periplasmic sugar-binding; Structural Genomics, PSI-Biology, Midwest Center; HET: GOL, MSE; 2.105A {Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)}
Probab=89.00  E-value=0.032  Score=55.66  Aligned_cols=91  Identities=11%  Similarity=-0.005  Sum_probs=54.2  Template_Neff=10.900

Q NP_000836.2     145 DKISGVIGAAASSV-SIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALG--WNYVSTL  221 (908)
Q Consensus       145 ~~v~~vIg~~~s~~-~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~--~~~v~ii  221 (908)
                      .++|++|....... .......+. .++|+|..+...+.      ......+..++...++.+++++.+.+  .++++++
T Consensus       237 ~~~dgii~~~~~~~~~~~~~~~~~-~~ipvv~~~~~~~~------~~~~~~v~~d~~~~g~~aa~~l~~~~~~~~~i~~i  309 (341)
T 5ER3_A          237 AKVDGIAISPIDPENQVAMINDAC-KVTPVICQDSDAPA------SRRKFYLGTSNYLAGRAAGKLIQEAIPEGGEVMLF  309 (341)
T ss_dssp             TTCSEEEECCSSGGGCHHHHHHHH-TTSCEEEESSCCTT------SCCSCEEECCHHHHHHHHHHHHHHHCTTCEEEEEE
T ss_pred             CCCCEEEECCCCHHHHHHHHHHHh-hCCCEEEEcCCCCc------ccCcEEEeCCHHHHHHHHHHHHHHHCCCCcEEEEE
Confidence            46787775433322 122233445 68999987754321      12345566777777888888875543  3788888


Q NP_000836.2     222 ASEG--NYGESGVEAFTQISREI  242 (908)
Q Consensus       222 ~~~~--~~~~~~~~~~~~~~~~~  242 (908)
                      ....  .....+.++|++.+++.
T Consensus       310 ~~~~~~~~~~~r~~g~~~~l~~~  332 (341)
T 5ER3_A          310 VGKMEVLNAQERSQGIMDELAGK  332 (341)
T ss_dssp             ESCTTSHHHHHHHHHHHHHHTTC
T ss_pred             ECCCCChhHHHHHHHHHHHHhcC
Confidence            7432  23445667777777664


No 323
>3QI7_A Putative transcriptional regulator; PERIPLASMIC BINDING PROTEIN-LIKE, STRUCTURAL GENOMICS; 1.86A {Clostridium difficile}
Probab=87.09  E-value=0.055  Score=54.67  Aligned_cols=152  Identities=12%  Similarity=0.065  Sum_probs=79.5  Template_Neff=9.900

Q NP_000836.2     145 DKISGVIGAAASSVSIMVANILRLFKIPQISYASTAPELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASE  224 (908)
Q Consensus       145 ~~v~~vIg~~~s~~~~~va~~~~~~~iP~Is~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~v~ii~~~  224 (908)
                      .++++++..............+...++|+|......+....-........+..++...++.+++++.+.+.++++++...
T Consensus        86 ~~~d~ii~~~~~~~~~~~i~~~~~~gi~~iii~~~~~~~~~v~~~~~~~~V~~D~~~~g~~a~~~l~~~g~~~i~~i~~~  165 (371)
T 3QI7_A           86 KEVQAIVVSTDQAGLLPALQKVKEKRPEIITISAPMGDDKNQLSQFVDVNLGVSAEERGKVLAERSKEMGAKAFIHYAST  165 (371)
T ss_dssp             TTEEEEEEECSSCCCHHHHHHHHHHCTTSEEEESSCCSCHHHHHHHSSEEEECCHHHHHHHHHHHHHHTTCSCEEEEEET
T ss_pred             CCCcEEEEeCCCCchHHHHHHHHHhCCCEEEEeCCCCCChhHHcccccEEEECChHHHHHHHHHHHHHCCCCEEEEEeCC
Confidence            46777775433322223334456678998877654321000000002344566666777778888766677788888743


Q NP_000836.2     225 GN----YGESGVEAFTQISREIGGVCIAQSQKIPREPRPGEFEKIIKRLL---------ETPNARAVIMFANEDDIRRIL  291 (908)
Q Consensus       225 ~~----~~~~~~~~~~~~~~~~~~i~v~~~~~~~~~~~~~~~~~~~~~l~---------~~~~~~viv~~~~~~~~~~~l  291 (908)
                      ..    ....+.++|++.+++. ++.+.......  .........+++++         ...++++|+.. ++..+..++
T Consensus       166 ~~~~~~~~~~R~~gf~~~l~~~-gi~~~~~~~~~--~~~~~~~~~~~~~l~~~~~~~~~~~~~~~ai~~~-~d~~a~g~~  241 (371)
T 3QI7_A          166 DDLKDVNIAKRLEMIKETCKNI-GLPFVQVNTPN--INTEEDKNKVKQFLNEDIEKQVKKYGKDINVFGV-NEYMDEVIL  241 (371)
T ss_dssp             TGGGSHHHHHHHHHHHHHHHHT-TCCEEEEEECC--CSSTHHHHHHHHHHHHHHHHHHHHHCSCCEEEES-SHHHHHHHH
T ss_pred             ccccchhHHHHHHHHHHHHHHc-CCCeeeeecCC--CCCHHHHHHHHHHHHHHHHHHHHHHCCcEEEEEc-ChhhHHHHH
Confidence            22    2456778888888875 35433211101  11111111222221         11346666654 344567788


Q NP_000836.2     292 EAAKKLNQS  300 (908)
Q Consensus       292 ~~~~~~g~~  300 (908)
                      +++++.|..
T Consensus       242 ~al~~~g~~  250 (371)
T 3QI7_A          242 TKALELKYI  250 (371)
T ss_dssp             HHHHHHCCB
T ss_pred             HHHHHCCCE
Confidence            888877763


No 324
>6U1N_R Muscarinic acetylcholine receptor M2,Vasopressin V2; Arrestin, GPCR, complex, signaling, SIGNALING; HET: SEP, 2CU, TPO;{Homo sapiens}
Probab=78.82  E-value=0.23  Score=52.20  Aligned_cols=34  Identities=15%  Similarity=0.117  Sum_probs=18.4  Template_Neff=11.800

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+.+...+-.+++= .-|.+.+.
T Consensus        99 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~Ry~~i~  133 (509)
T 6U1N_R           99 GPVVCDLWLALDYVVSNASVMNLLIISFDRYFCVT  133 (509)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHTTTHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhh
Confidence            36788888777665554443333333 33444443


No 325
>2Z73_A Rhodopsin; Visual pigment, Gq-type, G-Protein Coupled; HET: PLM, TWT, PC1, BOG, RET; 2.5A {Todarodes pacificus}
Probab=72.81  E-value=0.44  Score=48.80  Aligned_cols=33  Identities=15%  Similarity=0.097  Sum_probs=16.8  Template_Neff=11.900

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ...|.+..++..+++....-.+++ =..|...+.
T Consensus       105 ~~~c~~~~~~~~~~~~~s~~~~~~isi~R~~ai~  138 (448)
T 2Z73_A          105 FAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIG  138 (448)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            567887776665544433333332 234544443


No 326
>3AYN_A Rhodopsin; transmembrane protein, Photoreceptor, Chromophore, Glycoprotein; HET: PC1, PLM, BOG, RET; 2.7A {Todarodes pacificus}
Probab=72.81  E-value=0.44  Score=48.80  Aligned_cols=33  Identities=15%  Similarity=0.097  Sum_probs=16.8  Template_Neff=11.900

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ...|.+..++..+++....-.+++ =..|...+.
T Consensus       105 ~~~c~~~~~~~~~~~~~s~~~~~~isi~R~~ai~  138 (448)
T 3AYN_A          105 FAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIG  138 (448)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            567887776665544433333332 234544443


No 327
>6P9X_R Guanine nucleotide-binding protein G(s) subunit; GPCR, MEMBRANE PROTEIN;{Homo sapiens}
Probab=69.60  E-value=0.58  Score=47.67  Aligned_cols=27  Identities=4%  Similarity=0.007  Sum_probs=16.5  Template_Neff=10.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKT  670 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~  670 (908)
                      ....|.+..++..++....+..+++-.
T Consensus       177 ~~~~C~~~~~~~~~~~~~s~~~l~~ia  203 (427)
T 6P9X_R          177 NVGWCRLVTAAYNYFHVTNFFWMFGEG  203 (427)
T ss_dssp             TCHHHHHHHHHHHHHHHHHHHHHTTTH
T ss_pred             CchHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            457788877776655555555444443


No 328
>5X33_A LTB4 receptor,Lysozyme,LTB4 receptor (E.C.3.2.1.17); helix, MEMBRANE PROTEIN; HET: 7Y9; 3.7A {Cavia porcellus}
Probab=69.09  E-value=0.61  Score=48.96  Aligned_cols=18  Identities=17%  Similarity=0.259  Sum_probs=11.4  Template_Neff=11.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..+.+..
T Consensus        87 ~~~~C~~~~~~~~~~~~~  104 (523)
T 5X33_A           87 GLAGCRLCHYICGVSMYA  104 (523)
T ss_pred             chHHHHHHHHHHHHHHHH
Confidence            367788877766554443


No 329
>5XSZ_A Lysophosphatidic acid receptor 6a,Endolysin,receptor (E.C.3.2.1.17); alpha helical, membrane protein; HET: OLC; 3.2A {Danio rerio}
Probab=67.40  E-value=0.7  Score=47.60  Aligned_cols=34  Identities=15%  Similarity=0.193  Sum_probs=17.1  Template_Neff=12.000

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAA-LLTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~-l~~K~~ri~~if  677 (908)
                      ....|.+..++..+......-. ++.=..|.+.+.
T Consensus        96 ~~~~C~~~~~~~~~~~~~s~~~~~~iaidRy~ai~  130 (477)
T 5XSZ_A           96 GSLLCKLSVSLFYTNMYGSILFLTCISVDRFLAIV  130 (477)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CChHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3678888777665444332222 222334544444


No 330
>4PXZ_A P2Y purinoceptor 12, Soluble cytochrome; purinergic receptor P2Y12, agonist-bound, G-protein; HET: CLR, 6AD, OLC; 2.5A {Homo sapiens, Escherichia coli, Homo sapiens}
Probab=67.15  E-value=0.71  Score=47.32  Aligned_cols=34  Identities=21%  Similarity=0.307  Sum_probs=17.4  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+++ =..|.+.+.
T Consensus       102 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  136 (466)
T 4PXZ_A          102 RTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTT  136 (466)
T ss_dssp             HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888777665544433333333 233444443


No 331
>6IGK_A Endothelin receptor type B,Endolysin,Endothelin receptor; alpha helical, SIGNALING PROTEIN-PROTEIN BINDING; HET: CIT, OLC; 2.0A {Homo sapiens}
Probab=65.67  E-value=0.8  Score=47.49  Aligned_cols=34  Identities=9%  Similarity=0.173  Sum_probs=17.5  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.++ .=..|.+.+.
T Consensus       108 ~~~~C~~~~~~~~~~~~~s~~~~~~iaidR~~ai~  142 (498)
T 6IGK_A          108 GAEMCKLVPFIQKASVGITVLSLCALSIDRYRAVA  142 (498)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             chhHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            356788877766554443333332 2334544443


No 332
>3ODU_A C-X-C chemokine receptor type 4; Structural Genomics, PSI-2, Protein Structure; HET: OLC, OLA, ITD; 2.5A {Homo Sapiens, Enterobacteria phage T4}
Probab=65.54  E-value=0.8  Score=47.55  Aligned_cols=34  Identities=18%  Similarity=0.256  Sum_probs=18.7  Template_Neff=11.800

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAAL-LTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l-~~K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+ +.=.-|.+.+.
T Consensus       115 ~~~~C~~~~~~~~~~~~~s~~~~~~iaidRy~~i~  149 (502)
T 3ODU_A          115 GNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAIV  149 (502)
T ss_pred             chhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            46789888877665544333333 33334554444


No 333
>5T04_A Neurotensin receptor type 1,Endolysin,NEUROTENSIN RECEPTOR; MEMBRANE PROTEIN, G PROTEIN-COUPLED RECEPTOR; HET: PEG, TCE; 3.3A {Rattus norvegicus}
Probab=65.04  E-value=0.84  Score=47.61  Aligned_cols=16  Identities=6%  Similarity=-0.145  Sum_probs=10.0  Template_Neff=11.700

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..+.+.
T Consensus       107 ~~~C~~~~~~~~~~~~  122 (513)
T 5T04_A          107 DAGCRGYYFLRDACTY  122 (513)
T ss_pred             hHHHHHHHHHHHHHHH
Confidence            5678877666554443


No 334
>3ODU_B C-X-C chemokine receptor type 4; Structural Genomics, PSI-2, Protein Structure; HET: ITD, OLC, OLA; 2.5A {Homo Sapiens}
Probab=65.04  E-value=0.84  Score=47.38  Aligned_cols=35  Identities=14%  Similarity=0.200  Sum_probs=18.7  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYA-ALLTKTNRIHRIFE  678 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~-~l~~K~~ri~~if~  678 (908)
                      ....|.+..++..+++....- .++.=.-|.+.+.+
T Consensus       115 ~~~~C~~~~~~~~~~~~~s~~~~~~iaidR~~ai~~  150 (502)
T 3ODU_B          115 GNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAIVH  150 (502)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             cchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
Confidence            467888888776655443333 23333445554443


No 335
>3OE0_A C-X-C chemokine receptor type 4; Structural Genomics, PSI-2, Protein Structure; 2.9A {Homo Sapiens, Enterobacteria phage T4}
Probab=61.92  E-value=1  Score=46.52  Aligned_cols=34  Identities=15%  Similarity=0.206  Sum_probs=18.1  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAA-LLTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~-l~~K~~ri~~if  677 (908)
                      ....|.+..++..+++....-. ++.=.-|.+.+.
T Consensus       115 ~~~~C~~~~~~~~~~~~~s~~~l~~iaidRy~~i~  149 (499)
T 3OE0_A          115 GNFLCKAVHVIYTVNLYSSVWILAFISLDRYLAIV  149 (499)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3678888777766554433332 233334544444


No 336
>5T1A_A C-C chemokine receptor type 2; C-C Chemokine Receptor type 2; HET: SO4, 73R, VT5, YCM, OLC; 2.806A {Homo sapiens}
Probab=60.86  E-value=1.1  Score=46.45  Aligned_cols=34  Identities=15%  Similarity=0.207  Sum_probs=17.2  Template_Neff=11.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAAL-LTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l-~~K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+ +.=..|.+.+.
T Consensus       119 ~~~~C~~~~~~~~~~~~~s~~~l~~iaidRy~~i~  153 (508)
T 5T1A_A          119 GNAMCKLFTGLYHIGYFGGIFFIILLTIDRYLAIV  153 (508)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             CchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            36778887776654443333222 22334544444


No 337
>6K41_R Guanine nucleotide-binding protein G(o) subunit; GPCR, Complex, cryo-EM, MEMBRANE PROTEIN; HET: CZX; 2.9A {Homo sapiens}
Probab=60.42  E-value=1.2  Score=46.60  Aligned_cols=34  Identities=15%  Similarity=0.001  Sum_probs=15.1  Template_Neff=10.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.+++= .-|...+.
T Consensus       280 ~~~~C~~~~~l~~~~~~~s~~~l~~iai~R~~ai~  314 (512)
T 6K41_R          280 RRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVS  314 (512)
T ss_dssp             ----CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678887777665544433333332 33444443


No 338
>6K42_R Guanine nucleotide-binding protein G(i) subunit; GPCR, Complex, cryo-EM, MEMBRANE PROTEIN; HET: CZX; 4.1A {Bos taurus}
Probab=60.42  E-value=1.2  Score=46.60  Aligned_cols=34  Identities=15%  Similarity=0.001  Sum_probs=17.5  Template_Neff=10.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.+++= .-|...+.
T Consensus       280 ~~~~C~~~~~l~~~~~~~s~~~l~~iai~R~~ai~  314 (512)
T 6K42_R          280 RRTWCEVYLALDVLFCTSSIVHLCAISLDRYWAVS  314 (512)
T ss_dssp             CSTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678887777665544433333332 33444443


No 339
>5YC8_A Muscarinic acetylcholine receptor M2,Redesigned apo-cytochrome; GPCR crystallography, rationally thermostabilized mutant; HET: 3C0; 2.5A {Homo sapiens}
Probab=60.13  E-value=1.2  Score=44.60  Aligned_cols=18  Identities=6%  Similarity=0.071  Sum_probs=11.5  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..++...
T Consensus        94 ~~~~C~~~~~~~~~~~~~  111 (421)
T 5YC8_A           94 GPVVCDLWLALDYVVSNA  111 (421)
T ss_dssp             CHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHH
Confidence            367788877766554443


No 340
>6N4B_R Guanine nucleotide-binding protein G(i) subunit; Cannabinoid receptor, GPCR, synthetic cannabinoid; HET: KCA, CLR; 3.0A {Homo sapiens}
Probab=59.77  E-value=1.2  Score=46.18  Aligned_cols=18  Identities=6%  Similarity=0.296  Sum_probs=7.9  Template_Neff=10.800

Q NP_000836.2     587 PVFVAILGIIATTFVIVT  604 (908)
Q Consensus       587 ~~~~~~~~i~~~~~~~~~  604 (908)
                      ..++.++|++.-++++..
T Consensus       138 ~~ii~iigi~~N~lvl~~  155 (495)
T 6N4B_R          138 SLTLGTFTVLENLLVLCV  155 (495)
T ss_pred             HHHHHHHHHHHHHHHHHH
Confidence            344444555444443333


No 341
>3VW7_A Chimera of Proteinase-activated receptor 1; High resolution structure, protease-activated receptor; HET: OLC, VPX; 2.2A {Homo sapiens, Enterobacteria phage T4, Homo sapiens}
Probab=59.50  E-value=1.2  Score=45.59  Aligned_cols=34  Identities=15%  Similarity=0.224  Sum_probs=17.4  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.+++ =.-|.+.+.
T Consensus        89 ~~~~C~~~~~~~~~~~~~s~~~~~~iaidRy~ai~  123 (484)
T 3VW7_A           89 GSELCRFVTAAFYCNMYASILLMTVISIDRFLAVV  123 (484)
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            3567888777765544433333332 233444443


No 342
>6GPS_A C-C chemokine receptor type 2,Rubredoxin,C-C; GPCR, Signalling, Drug-design, SIGNALING PROTEIN; HET: F7N; 3.3A {Homo sapiens}
Probab=59.46  E-value=1.2  Score=44.63  Aligned_cols=23  Identities=9%  Similarity=0.160  Sum_probs=13.4  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAAL  666 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l  666 (908)
                      ....|.+..++..+++....-.+
T Consensus       108 ~~~~C~~~~~~~~~~~~~s~~~~  130 (429)
T 6GPS_A          108 GNAMCKLFTGLYHIGYFGGIFFI  130 (429)
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678887776665544433333


No 343
>6ME8_A Soluble cytochrome b562,Melatonin receptor type; GPCR, melatonin receptor type 1B; HET: JEY; 3.1A {Escherichia coli}
Probab=58.95  E-value=1.3  Score=45.24  Aligned_cols=26  Identities=15%  Similarity=0.132  Sum_probs=15.9  Template_Neff=11.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK  669 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K  669 (908)
                      ....|.+..++..+++...+-.+++-
T Consensus       185 ~~~~C~~~~~~~~~~~~~s~~~~~~i  210 (460)
T 6ME8_A          185 GEEHCKASAFVMGLSVIGSVWNITAI  210 (460)
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            36778888777766555444444443


No 344
>6ME6_A Soluble cytochrome b562,Melatonin receptor type; GPCR, melatonin receptor type 1B; HET: OLC, JEY; 2.8A {Escherichia coli}
Probab=58.34  E-value=1.3  Score=45.13  Aligned_cols=34  Identities=18%  Similarity=0.168  Sum_probs=17.1  Template_Neff=11.600

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+++ -.-|...+.
T Consensus       185 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  219 (460)
T 6ME6_A          185 GEEHCKASAFVMGLSVIGSVWNITAIAIDRYLYIC  219 (460)
T ss_dssp             CSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3667888777665544433333322 233444443


No 345
>4GRV_A Neurotensin receptor type 1, Neurotensin; G-protein coupled receptor, neurotensin receptor; HET: EPE; 2.802A {Rattus norvegicus, Enterobacteria phage T4}
Probab=58.13  E-value=1.4  Score=45.79  Aligned_cols=33  Identities=9%  Similarity=-0.115  Sum_probs=16.5  Template_Neff=11.800

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAA-LLTKTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~-l~~K~~ri~~if  677 (908)
                      ...|.+..++..+++....-. ++.=..|.+.+.
T Consensus       107 ~~~C~~~~~~~~~~~~~s~~~~~~iai~Ry~ai~  140 (510)
T 4GRV_A          107 DAGCRGYYFLRDACTYATALNVASLSVARYLAIC  140 (510)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            567887776655444333222 233344554444


No 346
>6WWZ_R Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit; GPCR, Chemokine, Chemokine receptor, Complex; 3.34A {Rattus norvegicus}
Probab=57.89  E-value=1.4  Score=46.26  Aligned_cols=33  Identities=12%  Similarity=0.192  Sum_probs=17.1  Template_Neff=10.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRI  676 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~i  676 (908)
                      ....|.+..++..+++...+-.++.- ..|...+
T Consensus       259 ~~~~C~~~~~~~~~~~~~s~~~l~~iaidRy~ai  292 (529)
T 6WWZ_R          259 SNATCKLLKGIYAINFNCGMLLLTCISMDRYIAI  292 (529)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678887777665554433333332 2344444


No 347
>5ZKC_A Muscarinic acetylcholine receptor M2,Apo-cytochrome b562; GPCR crystallography, rationally thermostabilized mutant; HET: 3C0; 2.3A {Homo sapiens}
Probab=57.52  E-value=1.4  Score=43.99  Aligned_cols=34  Identities=12%  Similarity=0.115  Sum_probs=17.5  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..++.....-.+++ =.-|...+.
T Consensus        94 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  128 (421)
T 5ZKC_A           94 GPVVCDLWLALDYVVSNARVMNLLIISFDRYFCVT  128 (421)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhh
Confidence            3678888877665554433333322 233444443


No 348
>5IU7_A Adenosine receptor A2a,Soluble cytochrome b562,Adenosine; G-protein-coupled receptor, integral membrane protein; HET: CLR, OLC, OLA, 6DY, OLB; 1.9A {Homo sapiens}
Probab=57.19  E-value=1.4  Score=44.21  Aligned_cols=17  Identities=18%  Similarity=0.092  Sum_probs=10.0  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..++..
T Consensus        82 ~~~~C~~~~~~~~~~~~   98 (433)
T 5IU7_A           82 ACHGCLFIACFVLVLAQ   98 (433)
T ss_pred             cchHHHHHHHHHHHHHH
Confidence            35567777766554443


No 349
>5NM4_A Lysozyme C (E.C.3.2.1.17); room-temperature, serial crystallography, Signaling protein; HET: ZMA, OLA, CLR; 1.7A {Homo sapiens}
Probab=57.15  E-value=1.4  Score=44.20  Aligned_cols=17  Identities=18%  Similarity=0.092  Sum_probs=10.0  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..++..
T Consensus        82 ~~~~C~~~~~~~~~~~~   98 (433)
T 5NM4_A           82 ACHGCLFIACFVLVLAQ   98 (433)
T ss_dssp             EHHHHHHHHHHHHHHHH
T ss_pred             ccchHHHHHHHHHHHHH
Confidence            35567777666554443


No 350
>5WIU_A D(4) dopamine receptor,Soluble cytochrome b562; GPCR, dopamine receptor, antagonist, sodium; HET: PEG, PO4, OLA, AQD; 1.962A {Homo sapiens}
Probab=56.40  E-value=1.5  Score=43.87  Aligned_cols=22  Identities=9%  Similarity=-0.076  Sum_probs=13.0  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAA  665 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~  665 (908)
                      ....|.+..++..+.+....-.
T Consensus       108 ~~~~C~~~~~~~~~~~~~s~~~  129 (422)
T 5WIU_A          108 SPRLCDALMAMDVMLCTASIFN  129 (422)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHHHHHHH
Confidence            3567888777765544433333


No 351
>5WIV_A D(4) dopamine receptor,Soluble cytochrome b562; GPCR, dopamine receptor, antagonist, sodium; HET: PEG, PO4, OLA, AQD; 2.143A {Homo sapiens}
Probab=56.40  E-value=1.5  Score=43.87  Aligned_cols=22  Identities=9%  Similarity=-0.076  Sum_probs=13.0  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAA  665 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~  665 (908)
                      ....|.+..++..+.+....-.
T Consensus       108 ~~~~C~~~~~~~~~~~~~s~~~  129 (422)
T 5WIV_A          108 SPRLCDALMAMDVMLCTASIFN  129 (422)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHHHHHHH
Confidence            3567888777765544433333


No 352
>5NDD_A Lysozyme,Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated; MEMBRANE PROTEIN, GPCR, 7TM; HET: 8TZ; 2.801A {Enterobacteria phage T4}
Probab=56.28  E-value=1.5  Score=46.94  Aligned_cols=34  Identities=21%  Similarity=0.221  Sum_probs=17.2  Template_Neff=11.000

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.+++ =.-|...+.
T Consensus       273 ~~~~C~~~~~l~~~~~~~s~~~l~~iaidRy~aI~  307 (619)
T 5NDD_A          273 GEALCNVLIGFFYANMYCSILFLTCLSVQRAWEIV  307 (619)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888777665544433333333 233444443


No 353
>4IB4_A Human 5-HT2B receptor_BRIL chimera; ergotamine, Novel protein engineering, GPCR; HET: CLR, PLM, OLA, ERM, PEG, OLC, OLB; 2.7A {Homo sapiens}
Probab=56.21  E-value=1.5  Score=43.85  Aligned_cols=34  Identities=18%  Similarity=0.037  Sum_probs=17.5  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+++ -.-|...+.
T Consensus        99 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  133 (430)
T 4IB4_A           99 PLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIK  133 (430)
T ss_dssp             CTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             cccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            3567888777765554433333333 233444443


No 354
>6AK3_A Prostaglandin E2 receptor EP3 subtype,Soluble; GPCR, lipid, signaling protein, prostanoid; HET: POV, P2E; 2.9A {Homo sapiens}
Probab=55.29  E-value=1.6  Score=43.47  Aligned_cols=19  Identities=16%  Similarity=0.140  Sum_probs=11.2  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFS  662 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~  662 (908)
                      ....|.+..++..+.+...
T Consensus        88 ~~~~c~~~~~~~~~~~~~s  106 (418)
T 6AK3_A           88 SGRLCTFFGLTMTVFGLSS  106 (418)
T ss_dssp             GGHHHHHHHHHHHHHHHHH
T ss_pred             CchhHHHHHHHHHHHHHHH
Confidence            3467887776665444433


No 355
>6AK3_B Prostaglandin E2 receptor EP3 subtype,Soluble; GPCR, lipid, signaling protein, prostanoid; HET: P2E, POV; 2.9A {Homo sapiens}
Probab=55.29  E-value=1.6  Score=43.47  Aligned_cols=19  Identities=16%  Similarity=0.140  Sum_probs=10.8  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFS  662 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~  662 (908)
                      ....|.+..++..+.+...
T Consensus        88 ~~~~c~~~~~~~~~~~~~s  106 (418)
T 6AK3_B           88 SGRLCTFFGLTMTVFGLSS  106 (418)
T ss_dssp             -CHHHHHHHHHHHHHHHHH
T ss_pred             CchhHHHHHHHHHHHHHHH
Confidence            3467887776665444433


No 356
>6M9T_A Prostaglandin E2 receptor EP3 subtype,Endolysin; GPCR, prostaglandin E2 receptor 3; HET: SO4, OLA, J9P, OLC; 2.5A {Homo sapiens}
Probab=54.94  E-value=1.7  Score=45.58  Aligned_cols=17  Identities=12%  Similarity=0.104  Sum_probs=10.2  Template_Neff=11.200

Q NP_000836.2     645 TIICSFRRVFLGLGMCF  661 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l  661 (908)
                      ...|.+..++..+++..
T Consensus       139 ~~~C~~~~~~~~~~~~~  155 (537)
T 6M9T_A          139 GRLCTFFGLTMTVFGLS  155 (537)
T ss_pred             hhHHHHHHHHHHHHHHH
Confidence            46777777665544443


No 357
>5ZKP_A Platelet-activating factor receptor,Flavodoxin; G protein-coupled receptor, Platelet-activating factor; HET: 9ER, FMN; 2.81A {Homo sapiens}
Probab=54.81  E-value=1.7  Score=44.22  Aligned_cols=34  Identities=18%  Similarity=0.216  Sum_probs=16.9  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..+......-.++ .=.-|.+.+.
T Consensus        88 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~Ry~~i~  122 (466)
T 5ZKP_A           88 PKFLCNVAGCLFFINTYCSVAFLGVITYNRYQAVT  122 (466)
T ss_pred             hhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            356788877765544433333322 2334444444


No 358
>5ZKQ_A Platelet-activating factor receptor; G protein-coupled receptor, Platelet-activating factor; HET: SO4, 9EU, OLC; 2.9A {Homo sapiens}
Probab=54.65  E-value=1.7  Score=43.68  Aligned_cols=18  Identities=6%  Similarity=0.264  Sum_probs=11.5  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..++...
T Consensus        88 ~~~~C~~~~~~~~~~~~~  105 (438)
T 5ZKQ_A           88 PKFLCNVAGCLFFINTYC  105 (438)
T ss_dssp             CHHHHHHHHHHHHHHHHH
T ss_pred             CHHHHHHHHHHHHHHHHH
Confidence            367788887766554443


No 359
>5W0P_C T4 lysozyme-human rhodopsin-mouse visual arrestin; rhodopsin, GPCR, arrestin, GRK, phosphorylation; HET: TPO, SEP, NAG; 3.013A {Enterobacteria phage RB55}
Probab=54.43  E-value=1.7  Score=49.17  Aligned_cols=21  Identities=19%  Similarity=0.278  Sum_probs=12.4  Template_Neff=10.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYA  664 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~  664 (908)
                      ....|.+..++..+.+...+-
T Consensus       266 ~~~~C~~~~~l~~~~~~~s~~  286 (906)
T 5W0P_C          266 GPTGCNLQGFFATLGGEIALW  286 (906)
T ss_pred             CchHHHHHHHHHHHHHHHHHH
Confidence            356788877766554443333


No 360
>5W0P_B T4 lysozyme-human rhodopsin-mouse visual arrestin; rhodopsin, GPCR, arrestin, GRK, phosphorylation; HET: SEP, NAG, TPO; 3.013A {Enterobacteria phage RB55}
Probab=54.02  E-value=1.8  Score=49.07  Aligned_cols=23  Identities=22%  Similarity=0.327  Sum_probs=13.4  Template_Neff=10.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAAL  666 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l  666 (908)
                      ....|.+..++..+.+...+-.+
T Consensus       266 ~~~~C~~~~~l~~~~~~~s~~~l  288 (906)
T 5W0P_B          266 GPTGCNLQGFFATLGGEIALWSL  288 (906)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHHHHHHHHHHH
Confidence            35678887776665544433333


No 361
>6OSA_R Neurotensin receptor type 1, JMV449; GPCR, G-protein, complex, SIGNALING PROTEIN;{Homo sapiens}
Probab=53.46  E-value=1.8  Score=43.48  Aligned_cols=16  Identities=6%  Similarity=-0.145  Sum_probs=9.8  Template_Neff=12.000

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..+++.
T Consensus       158 ~~~c~~~~~~~~~~~~  173 (435)
T 6OSA_R          158 DAGCRGYYFLRDACTY  173 (435)
T ss_pred             HHHHHHHHHHHHHHHH
Confidence            5678777666554443


No 362
>4U14_A Muscarinic acetylcholine receptor M3,Endolysin fusion; alpha helix, G protein-coupled receptors; HET: 0HK; 3.57A {Rattus norvegicus}
Probab=52.86  E-value=1.9  Score=43.86  Aligned_cols=22  Identities=9%  Similarity=0.028  Sum_probs=12.9  Template_Neff=11.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAA  665 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~  665 (908)
                      ....|.+..++..++.....-.
T Consensus        81 ~~~~C~~~~~~~~~~~~~s~~~  102 (460)
T 4U14_A           81 GNLACDLWLSIDYVASNASVMN  102 (460)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CccHHHHHHHHHHHHHHHHHHH
Confidence            3677888777666554433333


No 363
>5TUD_A Chimera protein of 5-hydroxytryptamine receptor; 7-TM, GPCR, Fab, complex, SIGNALING; HET: ERM; 3.0A {Homo sapiens}
Probab=52.52  E-value=1.9  Score=43.67  Aligned_cols=34  Identities=18%  Similarity=0.025  Sum_probs=17.1  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..+......-.++ .=.-|...+.
T Consensus       115 ~~~~C~~~~~~~~~~~~~s~~~~~~iaidR~~~i~  149 (457)
T 5TUD_A          115 PLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIK  149 (457)
T ss_dssp             CTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            356788877766544433333322 2334444443


No 364
>6C1R_B C5a anaphylatoxin chemotactic receptor 1; GPCR, MEMBRANE PROTEIN-INHIBITOR complex; HET: OLA, MLI, ZAL, EFD, OLC, YCM; 2.2A {Escherichia coli}
Probab=52.18  E-value=2  Score=43.13  Aligned_cols=34  Identities=26%  Similarity=0.328  Sum_probs=17.0  Template_Neff=11.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+++ -..|...+.
T Consensus       191 ~~~~C~~~~~~~~~~~~~s~~~~~~is~~R~~~i~  225 (422)
T 6C1R_B          191 GGAACSILPSLILLNMYASILLLATISADRFLLVF  225 (422)
T ss_dssp             CHHHHHHGGGHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            3567887777665544433333333 233444443


No 365
>6OL9_A Muscarinic acetylcholine receptor M5, T4; GPCR inhibitor complex, MEMBRANE PROTEIN; HET: P33, 0HK, OLA, OLC; 2.541A {Homo sapiens}
Probab=52.11  E-value=2  Score=44.03  Aligned_cols=16  Identities=6%  Similarity=0.185  Sum_probs=10.0  Template_Neff=11.600

Q NP_000836.2     644 DTIICSFRRVFLGLGM  659 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf  659 (908)
                      ....|.+..++..++.
T Consensus        81 ~~~~C~~~~~~~~~~~   96 (480)
T 6OL9_A           81 GSLACDLWLALDYVAS   96 (480)
T ss_dssp             CHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHH
Confidence            3567887776655444


No 366
>6LI0_A G-protein coupled receptor 52,Flavodoxin,G-protein coupled; Human GPR52 receptor, Class A; HET: FMN, FLC, OLC, EN6, PEG; 2.2A {Homo sapiens}
Probab=52.05  E-value=2  Score=43.78  Aligned_cols=34  Identities=15%  Similarity=0.198  Sum_probs=17.0  Template_Neff=11.800

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.++ .=.-|.+.+.
T Consensus        95 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  129 (468)
T 6LI0_A           95 ESLTCQVFGYIISVLKSVSMWCLACISVDRYLAIT  129 (468)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            466788877765544433333332 2333444443


No 367
>4XES_A neurotensin receptor subtype 1, lysozyme; membrane protein, G protein-coupled receptor; HET: PEG, GOL, CIT, EPE; 2.6A {Rattus norvegicus}
Probab=51.22  E-value=2.1  Score=44.65  Aligned_cols=33  Identities=9%  Similarity=-0.048  Sum_probs=16.5  Template_Neff=11.800

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ...|.+..++..+.+....-.+++ -.-|...+.
T Consensus       107 ~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  140 (541)
T 4XES_A          107 DAGCRGYYFLRDACTYATALNVASLSVARYLAIC  140 (541)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            567887776665544433333332 233444443


No 368
>6C1Q_B C5a anaphylatoxin chemotactic receptor 1; GPCR, MEMBRANE PROTEIN; HET: 9P2, YCM, ZAL; 2.9A {Escherichia coli}
Probab=50.95  E-value=2.1  Score=42.87  Aligned_cols=34  Identities=26%  Similarity=0.328  Sum_probs=16.9  Template_Neff=11.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+++ -..|...+.
T Consensus       191 ~~~~C~~~~~~~~~~~~~s~~~~~~is~~R~~~i~  225 (422)
T 6C1Q_B          191 GGAACSILPSLILLNMYASILLLATISADRFLLVF  225 (422)
T ss_pred             cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhh
Confidence            3567887777665544433333333 233444443


No 369
>3V2Y_A Sphingosine 1-phosphate receptor 1, Lysozyme; sphingosine, EDG receptor, lipid receptor; HET: NAG, ML5; 2.8A {Homo sapiens, Enterobacteria phage T4}
Probab=50.54  E-value=2.2  Score=44.40  Aligned_cols=33  Identities=15%  Similarity=0.082  Sum_probs=16.0  Template_Neff=11.000

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ...|.+..++..++.....-.+++= .-|.+.+.
T Consensus       132 ~~~c~~~~~~~~~~~~~s~~~l~~iaidRy~aI~  165 (520)
T 3V2Y_A          132 PAQWFLREGSMFVALSASVFSLLAIAIERYITML  165 (520)
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            4678777766554444333333332 23444443


No 370
>5UIW_A C-C chemokine receptor type 5,Rubredoxin,C-C; G-protein coupled receptor, Chemokine receptor; HET: OLC, OLA; 2.204A {Homo sapiens}
Probab=50.33  E-value=2.2  Score=42.19  Aligned_cols=19  Identities=11%  Similarity=0.266  Sum_probs=11.5  Template_Neff=12.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFS  662 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~  662 (908)
                      ....|.+..++..+++...
T Consensus        99 ~~~~c~~~~~~~~~~~~~s  117 (411)
T 5UIW_A           99 GNTMCQLLTGLYFIGFFSG  117 (411)
T ss_dssp             HHHHHHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHHHH
Confidence            3567887777665544433


No 371
>5OLZ_A Adenosine receptor A2a,Soluble cytochrome b562,Adenosine; G-Protein Coupled Receptor, Adenosine 2a; HET: TAR, CLR, OLA, T4E, OLC, PGE; 1.9A {Homo sapiens}
Probab=49.96  E-value=2.3  Score=42.63  Aligned_cols=16  Identities=19%  Similarity=0.104  Sum_probs=9.3  Template_Neff=12.200

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..+...
T Consensus        84 ~~~C~~~~~~~~~~~~   99 (434)
T 5OLZ_A           84 CHGCLFIACFVLVLAQ   99 (434)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHHHHHHH
Confidence            5567776666554433


No 372
>6P9Y_R Guanine nucleotide-binding protein G(s) subunit; GPCR, MEMBRANE PROTEIN;{Homo sapiens}
Probab=49.66  E-value=2.3  Score=43.79  Aligned_cols=30  Identities=20%  Similarity=0.252  Sum_probs=18.4  Template_Neff=9.900

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTKTNRIH  674 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~  674 (908)
                      ...|.+..++...+....+..+++-.+-.+
T Consensus       219 ~~~C~~~~~~~~~~~~~s~~wl~~iai~ry  248 (483)
T 6P9Y_R          219 TVECKAVMVFFHYCVVSNYFWLFIEGLYLF  248 (483)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            578888877766665555555555444333


No 373
>6MXT_A Fusion protein of Lysozyme and; G protein-coupled receptor, adrenergic receptor; HET: OLA, K5Y, OLC, P33, HTO, YCM; 2.95934213525A {Enterobacteria phage T4}
Probab=49.35  E-value=2.4  Score=43.36  Aligned_cols=34  Identities=21%  Similarity=0.215  Sum_probs=16.6  Template_Neff=11.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..++....+-.+++ =.-|...+.
T Consensus       237 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  271 (472)
T 6MXT_A          237 GNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAIT  271 (472)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            3567877776655444333333322 234444443


No 374
>6KUX_A alpha2A adrenergic receptor; alpha2A adrenergic receptor, antagonist, GPCR; HET: E3F, PEG, FLC; 2.7A {Spodoptera frugiperda}
Probab=48.92  E-value=2.4  Score=41.68  Aligned_cols=18  Identities=11%  Similarity=-0.077  Sum_probs=11.3  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..++...
T Consensus        83 ~~~~C~~~~~~~~~~~~~  100 (395)
T 6KUX_A           83 GKAWCEIYLALDVLFCTS  100 (395)
T ss_dssp             SHHHHHHHHHHHHHHHHH
T ss_pred             CchHHHHHHHHHHHHHHH
Confidence            356788877766554443


No 375
>4U15_B M3-mT4L, Tiotropium; GPCR T4L Stabillized Crystallography, MEMBRANE; HET: OLC, TAR, 0HK, P6G; 2.8A {Rattus norvegicus}
Probab=48.41  E-value=2.5  Score=42.07  Aligned_cols=18  Identities=6%  Similarity=0.032  Sum_probs=11.3  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..+++..
T Consensus        81 ~~~~C~~~~~~~~~~~~~   98 (418)
T 4U15_B           81 GNLACDLWLSIDYVASNA   98 (418)
T ss_dssp             CSHHHHHHHHHHHHHHHH
T ss_pred             cccHHHHHHHHHHHHHHH
Confidence            367788877766554443


No 376
>3EML_A Human Adenosine A2A receptor/T4 lysozyme; adenosine, caffeine, GPCR, membrane protein; HET: STE, ZMA, SO4; 2.6A {Homo sapiens, Enterobacteria phage T4, Homo sapiens}
Probab=48.34  E-value=2.5  Score=43.30  Aligned_cols=15  Identities=20%  Similarity=0.173  Sum_probs=9.0  Template_Neff=11.700

Q NP_000836.2     644 DTIICSFRRVFLGLG  658 (908)
Q Consensus       644 ~~~~C~~~~~~~~~g  658 (908)
                      ....|.+..++..+.
T Consensus        88 ~~~~C~~~~~l~~~~  102 (488)
T 3EML_A           88 ACHGCLFIACFVLVL  102 (488)
T ss_dssp             CHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHHH
Confidence            356677776665443


No 377
>6ORV_RP Guanine nucleotide-binding protein G(s) subunit; G-coupled protein receptor, GPCR, non-peptide; HET: N2V; 3.0A {Homo sapiens}
Probab=48.20  E-value=2.5  Score=43.60  Aligned_cols=34  Identities=15%  Similarity=0.304  Sum_probs=20.6  Template_Neff=9.600

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if  677 (908)
                      ....|.+..++........+.-+++-.+-+|...
T Consensus       231 ~~~~C~~~~~~~~~~~~as~~wl~~~al~l~~~i  264 (491)
T 6ORV_RP         231 DSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLL  264 (491)
T ss_pred             CcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3578888877766666555555555554444433


No 378
>3PBL_A D(3) dopamine receptor; Structural Genomics, PSI-2, PSI-Biology, Protein; HET: ETQ, MAL; 2.89A {Homo sapiens, Enterobacteria phage T4}
Probab=47.84  E-value=2.6  Score=43.15  Aligned_cols=33  Identities=15%  Similarity=0.089  Sum_probs=16.5  Template_Neff=11.500

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ...|.+..++..+......-.+++ =.-|.+.+.
T Consensus       109 ~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  142 (481)
T 3PBL_A          109 RICCDVFVTLDVMMCTASIWNLCAISIDRYTAVV  142 (481)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            567887776655444333333322 334444443


No 379
>6CMO_R Soluble cytochrome b562,Rhodopsin, Guanine nucleotide-binding; Rhodopsin  G protein ; HET: NAG;{Escherichia coli}
Probab=47.51  E-value=2.6  Score=42.94  Aligned_cols=34  Identities=18%  Similarity=0.261  Sum_probs=17.3  Template_Neff=10.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.++. -.-|...+.
T Consensus       246 ~~~~C~~~~~l~~~~~~~s~~~~~~isi~R~~ai~  280 (463)
T 6CMO_R          246 GPTGCNLQGFFATLGGEIALWSLVVLAIERYVVVC  280 (463)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CCchHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            3567888777666554433333332 233444443


No 380
>6B3J_R Guanine nucleotide-binding protein G(s) subunit; class B G protein-coupled receptor;{Homo sapiens}
Probab=46.45  E-value=2.8  Score=43.23  Aligned_cols=34  Identities=15%  Similarity=0.304  Sum_probs=20.6  Template_Neff=9.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if  677 (908)
                      ....|.+..++........+.-+++-.+-+|+..
T Consensus       231 ~~~~C~~~~~~~~~~~las~~wl~~~al~l~~~i  264 (491)
T 6B3J_R          231 DSLSCRLVFLLMQYCVAANYYWLLVEGVYLYTLL  264 (491)
T ss_pred             ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3578888877766666555555555554444433


No 381
>4LDE_A Lysozyme, Beta-2 adrenergic receptor (E.C.3.2.1.17); G protein coupled receptor, MEMBRANE; HET: P0G, 1WV; 2.79A {Enterobacteria phage T4, Homo sapiens}
Probab=45.08  E-value=3  Score=42.41  Aligned_cols=33  Identities=21%  Similarity=0.226  Sum_probs=16.8  Template_Neff=11.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRI  676 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~i  676 (908)
                      ....|.+..++....+...+-.+++- ..|...+
T Consensus       251 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i  284 (469)
T 4LDE_A          251 GNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI  284 (469)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678877776655544333333332 3344443


No 382
>5WF5_A Human A2a adenosine receptor_T4L chimera; human A2a adenosine receptor, D52N; HET: OLC, UKA; 2.6A {Homo sapiens}
Probab=44.86  E-value=3.1  Score=42.97  Aligned_cols=13  Identities=23%  Similarity=0.319  Sum_probs=7.7  Template_Neff=10.900

Q NP_000836.2     645 TIICSFRRVFLGL  657 (908)
Q Consensus       645 ~~~C~~~~~~~~~  657 (908)
                      ...|.+..++..+
T Consensus       105 ~~~C~~~~~l~~~  117 (504)
T 5WF5_A          105 CHGCLFIACFVLV  117 (504)
T ss_dssp             HHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHH
Confidence            4567776665443


No 383
>2R4R_A Beta-2 adrenergic receptor, antibody for; transmembrane helix, G-protein coupled receptor; 3.4A {Mus musculus}
Probab=44.84  E-value=3.1  Score=40.08  Aligned_cols=17  Identities=18%  Similarity=0.247  Sum_probs=10.5  Template_Neff=12.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..++..
T Consensus       102 ~~~~c~~~~~~~~~~~~  118 (365)
T 2R4R_A          102 GNFWCEFWTSIDVLCVT  118 (365)
T ss_pred             hhHHHHHHHHHHHHHHH
Confidence            35678777766554443


No 384
>5TGZ_A Cannabinoid receptor 1,Flavodoxin; Membrane protein, G protein-coupled receptor; HET: OLC, OLA, ZDG, FMN; 2.8A {Homo sapiens}
Probab=44.78  E-value=3.1  Score=42.00  Aligned_cols=20  Identities=10%  Similarity=0.353  Sum_probs=9.1  Template_Neff=11.700

Q NP_000836.2     585 VVPVFVAILGIIATTFVIVT  604 (908)
Q Consensus       585 ~~~~~~~~~~i~~~~~~~~~  604 (908)
                      ++..++.++|++.-++++..
T Consensus        27 ~~~~~~~~~gi~~N~~vl~~   46 (452)
T 5TGZ_A           27 VLSLTLGTFTVLENLLVLCV   46 (452)
T ss_pred             HHHHHHHHHHHHHHHHHHHH
Confidence            33444455555544444433


No 385
>3RZE_A Histamine H1 receptor/Lysozyme chimera; Structural Genomics, PSI-Biology, Membrane Protein; HET: PO4, D7V, 5EH, OLC; 3.1A {Homo sapiens, Enterobacteria phage T4}
Probab=44.72  E-value=3.1  Score=42.02  Aligned_cols=18  Identities=11%  Similarity=0.065  Sum_probs=11.4  Template_Neff=11.600

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..+++..
T Consensus        77 ~~~~C~~~~~l~~~~~~~   94 (452)
T 3RZE_A           77 GRPLCLFWLSMDYVASTA   94 (452)
T ss_dssp             HHHHHHHHHHHHHHHHHH
T ss_pred             CCcHHHHHHHHHHHHHHH
Confidence            467888877766544433


No 386
>6MEO_B Envelope glycoprotein gp160, T-cell surface; HIV coreceptor, MEMBRANE PROTEIN; HET: NAG, TYS, MAN, A2G, BMA; 3.9A {Human immunodeficiency virus 1}
Probab=44.70  E-value=3.1  Score=39.05  Aligned_cols=18  Identities=11%  Similarity=0.274  Sum_probs=10.9  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|....++...++..
T Consensus        97 ~~~~c~~~~~~~~~~~~~  114 (313)
T 6MEO_B           97 GNTMCQLLTGLYFIGFFS  114 (313)
T ss_pred             cHHHHHHHHHHHHHHHHH
Confidence            356788777665554443


No 387
>4ZUD_A Chimera protein of Soluble cytochrome; human Angiotensin Receptor AT1R, BRIL; HET: OLM; 2.8A {Escherichia coli}
Probab=44.48  E-value=3.1  Score=41.07  Aligned_cols=22  Identities=9%  Similarity=0.214  Sum_probs=12.9  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAA  665 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~  665 (908)
                      ....|.+..++..+++....-.
T Consensus       192 ~~~~c~~~~~~~~~~~~~s~~~  213 (410)
T 4ZUD_A          192 GNYLCKIASASVSFNLYASVFL  213 (410)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888777666554433333


No 388
>4IAR_A Chimera protein of human 5-hydroxytryptamine; ergotamine, Novel protein engineering, GPCR; HET: OLB, ERM; 2.7A {Homo sapiens, Escherichia coli}
Probab=44.43  E-value=3.2  Score=40.86  Aligned_cols=17  Identities=12%  Similarity=0.091  Sum_probs=10.8  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..++..
T Consensus        89 ~~~~C~~~~~~~~~~~~  105 (401)
T 4IAR_A           89 GQVVCDFWLSSDITCCT  105 (401)
T ss_dssp             HHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHH
Confidence            36778887776554443


No 389
>6D26_A Prostaglandin D2 receptor 2, Endolysin; GPCR, MEMBRANE PROTEIN-ANTAGONIST complex; HET: PGE, SIN, OLA, SO4, FSY, YCM; 2.798A {Homo sapiens}
Probab=44.14  E-value=3.2  Score=42.01  Aligned_cols=33  Identities=21%  Similarity=0.243  Sum_probs=17.1  Template_Neff=12.100

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ...|.+..++..+......-.+++ =..|.+.+.
T Consensus       102 ~~~C~~~~~~~~~~~~~s~~~~~~ia~~Ry~ai~  135 (470)
T 6D26_A          102 TTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVV  135 (470)
T ss_dssp             SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            567888777665544433333333 334544444


No 390
>6D27_A Prostaglandin D2 receptor 2, Endolysin; GPCR, MEMBRANE PROTEIN-ANTAGONIST complex; HET: MES, PGE, OLA, FT4, SO4, YCM, PGO; 2.738A {Homo sapiens}
Probab=44.14  E-value=3.2  Score=42.01  Aligned_cols=33  Identities=21%  Similarity=0.243  Sum_probs=17.1  Template_Neff=12.100

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ...|.+..++..+......-.+++ =..|.+.+.
T Consensus       102 ~~~C~~~~~~~~~~~~~s~~~~~~ia~~Ry~ai~  135 (470)
T 6D27_A          102 TTFCKLHSSIFFLNMFASGFLLSAISLDRCLQVV  135 (470)
T ss_dssp             SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            567888777665544433333333 334544444


No 391
>6A93_A 5-hydroxytryptamine receptor 2A,Soluble cytochrome b562; MEMBRANE PROTEIN; HET: CLR, PLM, 1PE, 8NU; 3.0A {Homo sapiens}
Probab=43.83  E-value=3.3  Score=40.22  Aligned_cols=18  Identities=11%  Similarity=-0.027  Sum_probs=11.3  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..++...
T Consensus        78 ~~~~C~~~~~~~~~~~~~   95 (376)
T 6A93_A           78 PSKLCAVWIYLDVLFSTA   95 (376)
T ss_dssp             CHHHHHHHHHHHHHHHHH
T ss_pred             ChhHHHHHHHHHHHHHHH
Confidence            356788877766544443


No 392
>6A94_A 5-hydroxytryptamine receptor 2A,Human Serotonin Receptor; receptor, MEMBRANE PROTEIN; HET: PLM, 1PE, ZOT, CLR, A6L; 2.9A {Homo sapiens}
Probab=43.83  E-value=3.3  Score=40.22  Aligned_cols=18  Identities=11%  Similarity=-0.027  Sum_probs=11.3  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..++...
T Consensus        78 ~~~~C~~~~~~~~~~~~~   95 (376)
T 6A94_A           78 PSKLCAVWIYLDVLFSTA   95 (376)
T ss_dssp             CTHHHHHHHHHHHHHHHH
T ss_pred             ChhHHHHHHHHHHHHHHH
Confidence            356788877766544443


No 393
>4IAQ_A 5-hydroxytryptamine receptor 1B; dihydroergotamine, Novel protein engineering, GPCR; HET: 2GM; 2.8A {Homo sapiens, Escherichia coli}
Probab=43.20  E-value=3.4  Score=40.64  Aligned_cols=18  Identities=11%  Similarity=0.043  Sum_probs=11.3  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..++...
T Consensus        89 ~~~~C~~~~~~~~~~~~~  106 (403)
T 4IAQ_A           89 GQVVCDFWLSSDITCCTA  106 (403)
T ss_dssp             HHHHHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHHH
Confidence            356788877766554443


No 394
>6KPG_R Guanine nucleotide-binding protein G(i) subunit; GPCR, G protein, cryo-EM, MEMBRANE; HET: 8D0;{Homo sapiens}
Probab=42.85  E-value=3.5  Score=41.88  Aligned_cols=18  Identities=6%  Similarity=0.329  Sum_probs=8.0  Template_Neff=11.600

Q NP_000836.2     586 VPVFVAILGIIATTFVIV  603 (908)
Q Consensus       586 ~~~~~~~~~i~~~~~~~~  603 (908)
                      +..+++++|++..++++.
T Consensus       166 ~~~~~~~~gi~~N~l~i~  183 (469)
T 6KPG_R          166 LSLTLGTFTVLENLLVLC  183 (469)
T ss_dssp             HHHHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHHhHHHHH
Confidence            334444555544444333


No 395
>4MQS_A Muscarinic acetylcholine receptor M2, Nanobody; G protein-coupled receptor, Muscarinic acetylcholine; HET: IXO; 3.5A {Homo sapiens}
Probab=42.44  E-value=3.5  Score=39.35  Aligned_cols=18  Identities=6%  Similarity=0.071  Sum_probs=11.0  Template_Neff=12.600

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..+++..
T Consensus       109 ~~~~c~~~~~~~~~~~~~  126 (351)
T 4MQS_A          109 GPVVCDLWLALDYVVSNA  126 (351)
T ss_pred             ChhHHHHHHHHHHHHHHH
Confidence            356787777665554443


No 396
>4DJH_B Kappa-type opioid receptor; JDtic, GPCR newtork, PSI-Biology, KOR; HET: JDC, OLC, CIT, PEG; 2.9A {Homo Sapiens}
Probab=42.33  E-value=3.6  Score=41.85  Aligned_cols=19  Identities=16%  Similarity=0.183  Sum_probs=11.6  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFS  662 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~  662 (908)
                      ....|.+..++..+++...
T Consensus        90 ~~~~C~~~~~~~~~~~~~s  108 (480)
T 4DJH_B           90 GDVLCKIVLSIDYYNMFTS  108 (480)
T ss_dssp             HHHHHHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHHHHHHH
Confidence            3567888777655544433


No 397
>6OS0_A Type-1 angiotensin II receptor,Soluble cytochrome; GPCR, nanobody, MEMBRANE PROTEIN; HET: NAG; 2.9A {Homo sapiens}
Probab=42.32  E-value=3.6  Score=40.84  Aligned_cols=34  Identities=15%  Similarity=0.222  Sum_probs=17.3  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAAL-LTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l-~~K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+ +.=.-|...+.
T Consensus       104 ~~~~C~~~~~~~~~~~~~s~~~~~~isi~R~~~i~  138 (425)
T 6OS0_A          104 GNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIV  138 (425)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35778887776655443333322 22334444443


No 398
>6OS1_A Type-1 angiotensin II receptor,Soluble cytochrome; GPCR, MEMBRANE PROTEIN; HET: CLR, OLC; 2.794A {Homo sapiens}
Probab=42.32  E-value=3.6  Score=40.84  Aligned_cols=34  Identities=15%  Similarity=0.222  Sum_probs=17.3  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAAL-LTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l-~~K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+ +.=.-|...+.
T Consensus       104 ~~~~C~~~~~~~~~~~~~s~~~~~~isi~R~~~i~  138 (425)
T 6OS1_A          104 GNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIV  138 (425)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35778887776655443333322 22334444443


No 399
>6OS2_A Type-1 angiotensin II receptor,Soluble cytochrome; GPCR, MEMBRANE PROTEIN; HET: CLR, OLC, NAG; 2.7A {Homo sapiens}
Probab=42.32  E-value=3.6  Score=40.84  Aligned_cols=34  Identities=15%  Similarity=0.222  Sum_probs=17.3  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAAL-LTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l-~~K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.+ +.=.-|...+.
T Consensus       104 ~~~~C~~~~~~~~~~~~~s~~~~~~isi~R~~~i~  138 (425)
T 6OS2_A          104 GNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIV  138 (425)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35778887776655443333322 22334444443


No 400
>4YAY_A human Angiotensin Receptor_Bril Chimera; XFEL, Serial Femtosecond Crystallography, human; HET: ZD7; 2.9A {Escherichia coli}
Probab=41.90  E-value=3.7  Score=40.60  Aligned_cols=25  Identities=12%  Similarity=0.218  Sum_probs=14.7  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT  668 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~  668 (908)
                      ....|.+..++..+++...+..++.
T Consensus       192 ~~~~c~~~~~~~~~~~~~s~~~~~~  216 (414)
T 4YAY_A          192 GNYLCKIASASVSFNLYASVFLLTC  216 (414)
T ss_dssp             TTHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888777766555444444433


No 401
>4N6H_A Soluble cytochrome b562, Delta-type opioid; human opioid receptor, sodium regulation; HET: OLA, PGE, TLA, OLC, EJ4; 1.8A {Escherichia coli, Homo sapiens}
Probab=41.57  E-value=3.7  Score=40.64  Aligned_cols=34  Identities=15%  Similarity=0.121  Sum_probs=16.7  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.++ .=..|...+.
T Consensus       193 ~~~~C~~~~~~~~~~~~~s~~~~~~ia~~R~~~i~  227 (414)
T 4N6H_A          193 GELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVC  227 (414)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CchhHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            356788777665544433333222 2234544444


No 402
>6AKX_B Neuropeptide Y receptor type 1,T4; G Protein-Coupled Receptor Chemokine Receptor; HET: A4R; 2.8A {Homo sapiens}
Probab=41.42  E-value=3.8  Score=39.78  Aligned_cols=22  Identities=9%  Similarity=0.150  Sum_probs=12.8  Template_Neff=12.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAA  665 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~  665 (908)
                      ....|.+..++..+++....-.
T Consensus        99 ~~~~c~~~~~~~~~~~~~s~~~  120 (381)
T 6AKX_B           99 GNTMCQLLTGLYFIGFFSGIFF  120 (381)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhhHHHHHHHHHHHHHHHHHHH
Confidence            3567887777665554443333


No 403
>6D9H_R Guanine nucleotide-binding protein G(i) subunit; signaling protein, membrane protein, active-state; HET: ADN;{Homo sapiens}
Probab=40.77  E-value=3.9  Score=40.00  Aligned_cols=16  Identities=6%  Similarity=-0.155  Sum_probs=9.4  Template_Neff=12.000

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..+.+.
T Consensus       132 ~~~C~~~~~~~~~~~~  147 (389)
T 6D9H_R          132 FHTCLMVACPVLILTQ  147 (389)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHHHHHHH
Confidence            4578777666554443


No 404
>6RZ4_A Cysteinyl leukotriene receptor 1,Soluble cytochrome; GPCR, LCP, MEMBRANE PROTEIN, cysteinyl; HET: KNT, OLC, OLA; 2.7A {Homo sapiens}
Probab=39.89  E-value=4.1  Score=40.33  Aligned_cols=35  Identities=14%  Similarity=0.081  Sum_probs=17.2  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYA-ALLTKTNRIHRIFE  678 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~-~l~~K~~ri~~if~  678 (908)
                      ....|.+..++..+......- .++.-.-|...+.+
T Consensus        95 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~~  130 (423)
T 6RZ4_A           95 GDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVF  130 (423)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
T ss_pred             cccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
Confidence            366788877665544333222 22333345444443


No 405
>6RZ5_B Cysteinyl leukotriene receptor 1,Soluble cytochrome; GPCR, LCP, MEMBRANE PROTEIN, cysteinyl; HET: 1PE, ZLK, OLA, OLC; 2.53A {Homo sapiens}
Probab=39.89  E-value=4.1  Score=40.33  Aligned_cols=35  Identities=14%  Similarity=0.081  Sum_probs=17.2  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYA-ALLTKTNRIHRIFE  678 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~-~l~~K~~ri~~if~  678 (908)
                      ....|.+..++..+......- .++.-.-|...+.+
T Consensus        95 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~~  130 (423)
T 6RZ5_B           95 GDFLCRLSTYALYVNLYCSIFFMTAMSFFRCIAIVF  130 (423)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
T ss_pred             cccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
Confidence            366788877665544333222 22333345444443


No 406
>5TVN_A 5-hydroxytryptamine receptor 2B,Soluble cytochrome b562,5-hydroxytryptamine; LSD, GPCR, serotonin receptor, MEMBRANE; HET: 7LD, OLC, CLR; 2.9A {Homo sapiens}
Probab=39.86  E-value=4.1  Score=39.89  Aligned_cols=34  Identities=18%  Similarity=0.015  Sum_probs=17.3  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..++.....-.+++= .-|...+.
T Consensus        84 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  118 (402)
T 5TVN_A           84 PLVLCPAWLFLDVLFSTASIWHLCAISVDRYIAIK  118 (402)
T ss_dssp             CSTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CccchhHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678887776655444333333332 23444443


No 407
>5UZ7_R Guanine nucleotide-binding protein G(s) subunit; Class B G protein-coupled receptor; 4.1A {Homo sapiens}
Probab=39.51  E-value=4.3  Score=41.89  Aligned_cols=27  Identities=19%  Similarity=0.292  Sum_probs=15.2  Template_Neff=10.000

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTKTN  671 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K~~  671 (908)
                      ...|.+..++..+.....+..+++-++
T Consensus       224 ~~~C~~~~~l~~~~~~~s~~wl~~iai  250 (501)
T 5UZ7_R          224 PVSCKILHFFHQYMMACNYFWMLCEGI  250 (501)
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            467887776665554444444444443


No 408
>6I9K_A Kumopsin1; Rhodopsin, GPCR, Light-sensitive, Retinal, MEMBRANE; HET: RET, OLC; 2.145A {Hasarius adansoni}
Probab=38.98  E-value=4.4  Score=39.30  Aligned_cols=17  Identities=12%  Similarity=0.123  Sum_probs=10.3  Template_Neff=12.400

Q NP_000836.2     645 TIICSFRRVFLGLGMCF  661 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l  661 (908)
                      ...|.+..++..+++..
T Consensus       120 ~~~c~~~~~~~~~~~~~  136 (380)
T 6I9K_A          120 PFMCELYGMIGSLFGSA  136 (380)
T ss_pred             HHHHHHHHHHHHHHHHH
Confidence            56787776665554433


No 409
>4XNV_A P2Y purinoceptor 1, Rubredoxin; human P2Y1 receptor, G protein; HET: CLR, BUR, 1PE, OLC, Y01; 2.2A {Homo sapiens}
Probab=38.66  E-value=4.5  Score=40.04  Aligned_cols=33  Identities=15%  Similarity=0.288  Sum_probs=16.8  Template_Neff=12.200

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ...|.+..++..+++....-.+++- .-|...+.
T Consensus       120 ~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  153 (421)
T 4XNV_A          120 DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVV  153 (421)
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            5678887776665544333333332 33444443


No 410
>4XNW_C P2Y purinoceptor 1, Rubredoxin; human P2Y1 receptor, G protein; HET: 2ID; 2.7A {Homo sapiens}
Probab=38.66  E-value=4.5  Score=40.04  Aligned_cols=33  Identities=15%  Similarity=0.288  Sum_probs=16.8  Template_Neff=12.200

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ...|.+..++..+++....-.+++- .-|...+.
T Consensus       120 ~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  153 (421)
T 4XNW_C          120 DAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVV  153 (421)
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            5678887776665544333333332 33444443


No 411
>5WB1_A Envelope protein US28,nanobody 7; chemokine receptor, MEMBRANE PROTEIN; 3.508A {Human cytomegalovirus}
Probab=38.12  E-value=4.6  Score=40.62  Aligned_cols=34  Identities=15%  Similarity=0.208  Sum_probs=17.1  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+++...+-.++.- .-|...+.
T Consensus       108 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  142 (458)
T 5WB1_A          108 ASVPCTLLTACFYVAMFASLCFITEIALDRYYAIV  142 (458)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             cchhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678877666555444433333332 33444443


No 412
>6LI1_A G-protein coupled receptor 52,Flavodoxin,G-protein coupled; Human GPR52 receptor, Class A; HET: PGE, OLC, FMN; 2.9A {Homo sapiens}
Probab=38.11  E-value=4.6  Score=40.55  Aligned_cols=34  Identities=15%  Similarity=0.199  Sum_probs=17.9  Template_Neff=11.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..++.....-.+++ =.-|.+.+.
T Consensus        95 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  129 (449)
T 6LI1_A           95 ESLTCQVFGYIISVLKSVSMWCLACISVDRYLAIT  129 (449)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            4677888777665544433333333 334444444


No 413
>5UNG_B Soluble cytochrome b562,Type-2 angiotensin II; human Angiotensin II receptor complex; HET: OLC, OLA, 8ES; 2.8A {Escherichia coli}
Probab=38.07  E-value=4.6  Score=39.71  Aligned_cols=33  Identities=21%  Similarity=0.351  Sum_probs=17.1  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRI  676 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~i  676 (908)
                      ....|.+..++..+++....-.++.- ..|...+
T Consensus       189 ~~~~c~~~~~~~~~~~~~s~~~~~~ia~~R~~~i  222 (411)
T 5UNG_B          189 GPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSV  222 (411)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678887776665554433333332 2344443


No 414
>5UNF_A Soluble cytochrome b562,Type-2 angiotensin II; human Angiotensin II receptor complex; HET: 8ES; 2.8A {Escherichia coli}
Probab=37.89  E-value=4.7  Score=39.75  Aligned_cols=25  Identities=24%  Similarity=0.344  Sum_probs=14.0  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT  668 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~  668 (908)
                      ....|.+..++..+++....-.++.
T Consensus       189 ~~~~c~~~~~~~~~~~~~s~~~~~~  213 (411)
T 5UNF_A          189 GPVMCKVFGSFLTLNMFASIFFITC  213 (411)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hhHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567887777666555444333333


No 415
>6J21_A Substance-P receptor (E.C.3.2.1.17),Endolysin; GPCR, Complex, Antagonist, signalling protein; HET: GBQ, OLC; 3.2A {Homo sapiens}
Probab=37.85  E-value=4.7  Score=40.12  Aligned_cols=34  Identities=18%  Similarity=0.236  Sum_probs=16.7  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..++.....-.++ .=.-|...+.
T Consensus       100 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~Ry~~i~  134 (441)
T 6J21_A          100 GLFYCKFHNFFPIAAVFASIWSMTAVAFDRYMAII  134 (441)
T ss_pred             cchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            356788877665544433332222 2334444443


No 416
>5ZHP_A Muscarinic acetylcholine receptor M3,Lysozyme,Muscarinic acetylcholine; G protein coupled receptor, MEMBRANE; HET: MAL, CIT, PG4, 9EC, P6G; 3.1A {Rattus norvegicus}
Probab=37.68  E-value=4.7  Score=39.82  Aligned_cols=17  Identities=6%  Similarity=0.079  Sum_probs=10.5  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..+...
T Consensus        81 ~~~~C~~~~~~~~~~~~   97 (418)
T 5ZHP_A           81 GNLACDLWLSIDYVASN   97 (418)
T ss_dssp             CHHHHHHHHHHHHHHHH
T ss_pred             cccHHHHHHHHHHHHHH
Confidence            35678877776554443


No 417
>5NJ6_A Lysozyme,Proteinase-activated receptor 2,Soluble cytochrome b562,Proteinase-activated; MEMBRANE PROTEIN, GPCR, 7TM; 4.0A {Homo sapiens}
Probab=37.61  E-value=4.7  Score=40.08  Aligned_cols=34  Identities=21%  Similarity=0.221  Sum_probs=16.8  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+......-.+++ =.-|...+.
T Consensus        91 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  125 (437)
T 5NJ6_A           91 GEALCNVLIGFFYANMYCSILFLTCLSVQRAWEIV  125 (437)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888776655544333333322 333444443


No 418
>5DSG_B Muscarinic acetylcholine receptor M4,Endolysin,Muscarinic acetylcholine; Membrane, GPCR, Signaling, Antagonist, MEMBRANE; HET: P6G, OLC, 0HK, PG6, EDT, OLA; 2.6A {Homo sapiens}
Probab=37.28  E-value=4.8  Score=39.81  Aligned_cols=17  Identities=6%  Similarity=0.130  Sum_probs=10.4  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..+++.
T Consensus        82 ~~~~C~~~~~~~~~~~~   98 (422)
T 5DSG_B           82 GAVVCDLWLALDYVVSN   98 (422)
T ss_dssp             HHHHHHHHHHHHHHHHH
T ss_pred             cHHHHHHHHHHHHHHHH
Confidence            36678877776554443


No 419
>4Z36_A Lysophosphatidic Acid Receptor 1, cytochrome; human lysophosphatidic acid receptor 1; HET: 1WV, ON3; 2.9A {Homo sapiens}
Probab=37.22  E-value=4.9  Score=40.64  Aligned_cols=34  Identities=15%  Similarity=0.156  Sum_probs=15.9  Template_Neff=11.200

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSY-AALLTKTNRIHRIFE  678 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~-~~l~~K~~ri~~if~  678 (908)
                      ...|.+..++..+...... ..++.-.-|.+.+.+
T Consensus       136 ~~~c~~~~~l~~~~~~~s~~~l~~isidRy~aI~~  170 (459)
T 4Z36_A          136 VSTWLLRQGLIDTSLTASVANLLAIAIERHITVFR  170 (459)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHc
Confidence            4578777666554333222 222233345544443


No 420
>6PT0_R Cannabinoid receptor 2, Guanine nucleotide-binding; GPCR complex, WIN55, 212-2, MEMBRANE; HET: WI5, CLR, PLM; 3.2A {Homo sapiens}
Probab=36.97  E-value=4.9  Score=38.72  Aligned_cols=12  Identities=0%  Similarity=-0.097  Sum_probs=5.9  Template_Neff=12.300

Q NP_000836.2     645 TIICSFRRVFLG  656 (908)
Q Consensus       645 ~~~C~~~~~~~~  656 (908)
                      ...|....++..
T Consensus       103 ~~~~~~~~~~~~  114 (369)
T 6PT0_R          103 KAVFLLKIGSVT  114 (369)
T ss_dssp             HHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHH
Confidence            445655554443


No 421
>6OIJ_R Guanine nucleotide-binding protein G(i) subunit; G-protein coupled receptor-G-protein complex, neurotransmitter; HET: Y01, IXO; 3.3A {Homo sapiens}
Probab=36.53  E-value=5.1  Score=38.43  Aligned_cols=34  Identities=18%  Similarity=0.165  Sum_probs=16.6  Template_Neff=12.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.++. -.-|...+.
T Consensus       103 ~~~~c~~~~~~~~~~~~~s~~~~~~i~~~R~~~i~  137 (363)
T 6OIJ_R          103 GTLACDLWLALDYVASQASVMNLLLISFDRYFSVT  137 (363)
T ss_pred             cchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567877766655444433333322 233444444


No 422
>4Z35_A Lysophosphatidic Acid Receptor 1, cytochrome; human lysophosphatidic acid receptor 1; HET: ON9, 1WV; 2.9A {Homo sapiens}
Probab=36.39  E-value=5.1  Score=40.54  Aligned_cols=14  Identities=7%  Similarity=0.083  Sum_probs=8.0  Template_Neff=11.200

Q NP_000836.2     645 TIICSFRRVFLGLG  658 (908)
Q Consensus       645 ~~~C~~~~~~~~~g  658 (908)
                      ...|.+..++..++
T Consensus       136 ~~~c~~~~~l~~~~  149 (464)
T 4Z35_A          136 VSTWLLRQGLIDTS  149 (464)
T ss_pred             HHHHHHHHHHHHHH
Confidence            45677666554443


No 423
>6KR8_A beta 2 adrenergic receptor; G-protein coupled receptor, b2AR, full; NMR {Homo sapiens}
Probab=36.37  E-value=5.1  Score=37.80  Aligned_cols=34  Identities=21%  Similarity=0.187  Sum_probs=16.9  Template_Neff=12.600

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..+++....-.++ .-..|...+.
T Consensus        79 ~~~~c~~~~~~~~~~~~~s~~~~~~ia~~R~~~i~  113 (336)
T 6KR8_A           79 GNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAIC  113 (336)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCC
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhh
Confidence            356788777766554433333222 2334444443


No 424
>6IIU_A Soluble cytochrome b562,Thromboxane A2 receptor,Rubredoxin,Thromboxane; GPCR, Complex, Antagonist, SIGNALING PROTEIN; HET: CLR, A8X, OLC; 2.5A {Escherichia coli}
Probab=36.22  E-value=5.2  Score=40.63  Aligned_cols=24  Identities=4%  Similarity=0.173  Sum_probs=11.7  Template_Neff=11.800

Q NP_000836.2     585 VVPVFVAILGIIATTFVIVTFVRY  608 (908)
Q Consensus       585 ~~~~~~~~~~i~~~~~~~~~~~~~  608 (908)
                      ++..++.++|++..++.++.+...
T Consensus       136 ~~~~~~~~lgi~~N~~~l~~~~~~  159 (484)
T 6IIU_A          136 WFAASFCVVGLASNLLALSVLAGA  159 (484)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHcc
Confidence            444455555655554444444433


No 425
>6IIV_A Soluble cytochrome b562,Thromboxane A2 receptor,Rubredoxin,Thromboxane; GPCR, Complex, Antagonist, SIGNALING PROTEIN; HET: CLR, A90; 3.0A {Escherichia coli}
Probab=36.22  E-value=5.2  Score=40.63  Aligned_cols=24  Identities=4%  Similarity=0.173  Sum_probs=11.7  Template_Neff=11.800

Q NP_000836.2     585 VVPVFVAILGIIATTFVIVTFVRY  608 (908)
Q Consensus       585 ~~~~~~~~~~i~~~~~~~~~~~~~  608 (908)
                      ++..++.++|++..++.++.+...
T Consensus       136 ~~~~~~~~lgi~~N~~~l~~~~~~  159 (484)
T 6IIV_A          136 WFAASFCVVGLASNLLALSVLAGA  159 (484)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHcc
Confidence            444455555655554444444433


No 426
>6E3Y_R Calcitonin gene-related peptide 1, Nanobody; class B G protein-coupled receptor; 3.3A {Lama glama}
Probab=36.12  E-value=5.2  Score=41.00  Aligned_cols=25  Identities=16%  Similarity=0.236  Sum_probs=13.8  Template_Neff=10.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT  668 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~  668 (908)
                      ....|.+..++..+.....+.-+++
T Consensus       218 ~~~~C~~~~~l~~~~~~as~~wl~~  242 (490)
T 6E3Y_R          218 NPVSCKVSQFIHLYLMGCNYFWMLC  242 (490)
T ss_dssp             CCHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             ChHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3577887776655544443333333


No 427
>6UUN_R Guanine nucleotide-binding protein G(s) subunit; GPCR, adrenomedullin receptor complex, MEMBRANE;{Homo sapiens}
Probab=36.12  E-value=5.2  Score=41.00  Aligned_cols=25  Identities=16%  Similarity=0.236  Sum_probs=13.8  Template_Neff=10.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT  668 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~  668 (908)
                      ....|.+..++..+.....+.-+++
T Consensus       218 ~~~~C~~~~~l~~~~~~as~~wl~~  242 (490)
T 6UUN_R          218 NPVSCKVSQFIHLYLMGCNYFWMLC  242 (490)
T ss_dssp             CCHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             ChHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3577887776655544443333333


No 428
>6M1I_A Ribonuclease 3 (E.C.3.1.26.3), Microprocessor complex; GPCR, PROTEIN BINDING; 3.5A {Homo sapiens}
Probab=35.51  E-value=5.4  Score=39.54  Aligned_cols=28  Identities=21%  Similarity=0.265  Sum_probs=17.2  Template_Neff=10.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTN  671 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~  671 (908)
                      ....|.+..++..++....+..+++-++
T Consensus       184 ~~~~C~~~~~~~~~~~~~s~~~l~~ia~  211 (406)
T 6M1I_A          184 STVECKAVMVFFHYCVVSNYFWLFIEGL  211 (406)
T ss_dssp             CCSHHHHHHHHHHHHHHTTTTTTHHHHH
T ss_pred             CHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3578888877766655555555554443


No 429
>4XT1_A US28, CX3CL1, nanobody 7; GPCR, chemokine, membrane protein, complex; HET: CLR, UNL, OLC; 2.886A {Cytomegalovirus}
Probab=35.42  E-value=5.4  Score=38.30  Aligned_cols=35  Identities=14%  Similarity=0.192  Sum_probs=17.1  Template_Neff=12.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIFE  678 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if~  678 (908)
                      ....|.+..++...++....-.++. -.-|...+.+
T Consensus       108 ~~~~C~~~~~~~~~~~~~s~~~~~~i~~~R~~~i~~  143 (362)
T 4XT1_A          108 ASVPCTLLTACFYVAMFASLCFITEIALDRYYAIVY  143 (362)
T ss_dssp             -CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTS
T ss_pred             CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHc
Confidence            3567877766655444433333332 3345444443


No 430
>6LW5_A N-formyl peptide receptor 2,Soluble cytochrome; Formyl peptide receptor, G protein-coupled; HET: CLR; 2.8A {Escherichia coli}
Probab=35.22  E-value=5.5  Score=39.58  Aligned_cols=18  Identities=11%  Similarity=0.361  Sum_probs=10.6  Template_Neff=11.700

Q NP_000836.2     645 TIICSFRRVFLGLGMCFS  662 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~  662 (908)
                      ...|.+..++..+++...
T Consensus       200 ~~~C~~~~~~~~~~~~~s  217 (427)
T 6LW5_A          200 WFLCKLIHIVVDINLFGS  217 (427)
T ss_dssp             HHHHHHHHHHHHHHHHHH
T ss_pred             ccHHHHHHHHHHHHHHHH
Confidence            456877776655444433


No 431
>5VBL_B agonist peptide,Rubredoxin-Apelin receptor chimera; human apelin receptor complex, agonist; HET: ALC, OLC, 200, HRG, OIC; 2.6A {Homo sapiens}
Probab=34.87  E-value=5.6  Score=39.04  Aligned_cols=34  Identities=21%  Similarity=0.230  Sum_probs=17.0  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.++.- .-|...+.
T Consensus       116 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  150 (407)
T 5VBL_B          116 GTFFCKLSSYLIFVNMYASAFCLTGLSFDRYLAIV  150 (407)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             cchhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35678887766655444333333332 33444443


No 432
>5V54_B OB-1 fused 5-HT1b receptor; 5-hydroxytryptamine, GPCR antagonist, OB1, ELECTRON; HET: 89F; 3.9A {Homo sapiens}
Probab=34.66  E-value=5.7  Score=38.71  Aligned_cols=34  Identities=18%  Similarity=0.068  Sum_probs=16.9  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..++.....-.+++ =.-|...+.
T Consensus        82 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  116 (395)
T 5V54_B           82 GQVVCDFWLSSDITCCTASIWHLCVIALDRYWAIT  116 (395)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTT
T ss_pred             chhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888777655444333333333 233444443


No 433
>5WB2_A Envelope protein US28,nanobody 7, CX3CL1; chemokine receptor, engineered proteins, MEMBRANE; HET: YCM, MES, CLR, OLC; 3.5A {Human cytomegalovirus}
Probab=34.21  E-value=5.8  Score=39.81  Aligned_cols=34  Identities=15%  Similarity=0.208  Sum_probs=17.1  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+++....-.++.- .-|...+.
T Consensus       107 ~~~~C~~~~~~~~~~~~~s~~~~~~ia~~R~~~i~  141 (460)
T 5WB2_A          107 ASVPCTLLTACFYVAMFASLCFITEIALDRYYAIV  141 (460)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             cchHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHH
Confidence            35678877766655444333333332 33444443


No 434
>6IBB_A Succinate receptor 1, Nanobody6; SUCNR1 GPR91 GPCR G-Protein coupled; HET: GOL, OLC, CLR, H95; 2.12A {Rattus norvegicus}
Probab=33.17  E-value=6.2  Score=37.34  Aligned_cols=34  Identities=18%  Similarity=0.179  Sum_probs=17.1  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++....+....-.++. -..|...+.
T Consensus        94 ~~~~c~~~~~~~~~~~~~s~~~~~~ia~~R~~~i~  128 (342)
T 6IBB_A           94 GDVLCISNRYVLHANLYTSILFLTFISIDRYLLMK  128 (342)
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567887776665544333333333 234444443


No 435
>4GBR_A Beta-2 adrenergic receptor, Lysozyme (E.C.3.2.1.17); 7 transmembrane helices, G-protein coupled; HET: CAU; 3.993A {Homo sapiens}
Probab=32.99  E-value=6.3  Score=36.36  Aligned_cols=17  Identities=18%  Similarity=0.247  Sum_probs=10.3  Template_Neff=12.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|....++...+..
T Consensus        74 ~~~~c~~~~~~~~~~~~   90 (309)
T 4GBR_A           74 GNFWCEFWTSIDVLCVT   90 (309)
T ss_pred             chhHHHHHHHHHHHHHH
Confidence            35678777766554443


No 436
>6NBF_R Parathyroid hormone/parathyroid hormone-related peptide receptor; Parathyroid hormone receptor, GPCR, Class; HET: CLR, PLM; 3.0A {Homo sapiens}
Probab=32.16  E-value=6.7  Score=40.00  Aligned_cols=29  Identities=17%  Similarity=0.206  Sum_probs=17.2  Template_Neff=9.800

Q NP_000836.2     646 IICSFRRVFLGLGMCFSYAALLTKTNRIH  674 (908)
Q Consensus       646 ~~C~~~~~~~~~gf~l~~~~l~~K~~ri~  674 (908)
                      ..|.+...+...+....+.-+++-.+-.|
T Consensus       253 ~~C~~~~~l~~~~~~~s~~wl~~~al~~~  281 (478)
T 6NBF_R          253 AGCRVAVTFFLYFLATNYYWILVEGLYLH  281 (478)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            67888777766665555555555444333


No 437
>6NBH_R Parathyroid hormone/parathyroid hormone-related peptide receptor; Parathyroid hormone receptor, GPCR, Class; HET: CLR, PLM; 3.5A {Homo sapiens}
Probab=32.16  E-value=6.7  Score=40.00  Aligned_cols=29  Identities=17%  Similarity=0.206  Sum_probs=17.2  Template_Neff=9.800

Q NP_000836.2     646 IICSFRRVFLGLGMCFSYAALLTKTNRIH  674 (908)
Q Consensus       646 ~~C~~~~~~~~~gf~l~~~~l~~K~~ri~  674 (908)
                      ..|.+...+...+....+.-+++-.+-.|
T Consensus       253 ~~C~~~~~l~~~~~~~s~~wl~~~al~~~  281 (478)
T 6NBH_R          253 AGCRVAVTFFLYFLATNYYWILVEGLYLH  281 (478)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            67888777766665555555555444333


No 438
>6LML_R Guanine nucleotide-binding protein G(i) subunit; glucagon receptor, GPCR, Gi1 protein;{Homo sapiens}
Probab=31.93  E-value=6.8  Score=39.09  Aligned_cols=34  Identities=24%  Similarity=0.451  Sum_probs=22.0  Template_Neff=10.300

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFE  678 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if~  678 (908)
                      ...|.+..++........+.-+++-.+-+++.+.
T Consensus       195 ~~~C~~~~~~~~~~~~~s~~w~~~~~~~l~~~i~  228 (422)
T 6LML_R          195 VAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLG  228 (422)
T ss_dssp             CTHHHHHHHHHHHHTTTTTTHHHHHHHHHHHHTT
T ss_pred             hhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            4788888777776666666666665555555443


No 439
>6WHC_R Guanine nucleotide-binding protein G(s) subunit; GPCR, receptor complex, MEMBRANE PROTEIN;{Homo sapiens}
Probab=31.83  E-value=6.8  Score=39.91  Aligned_cols=34  Identities=24%  Similarity=0.451  Sum_probs=22.5  Template_Neff=9.900

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFE  678 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if~  678 (908)
                      ...|.+..++........+.-+++-.+-+|+...
T Consensus       221 ~~~C~~~~~~~~~~~~~s~~wl~~~~l~l~~~i~  254 (477)
T 6WHC_R          221 VAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLG  254 (477)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3688888877777666666666666655555443


No 440
>6LI2_A G-protein coupled receptor 52,Rubredoxin,G-protein coupled; Human GPR52 receptor, Class A; HET: OLC; 2.8A {Homo sapiens}
Probab=31.69  E-value=6.8  Score=37.61  Aligned_cols=34  Identities=15%  Similarity=0.199  Sum_probs=17.6  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.++. =.-|...+.
T Consensus        95 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  129 (372)
T 6LI2_A           95 ESLTCQVFGYIISVLKSVSMWCLACISVDRYLAIT  129 (372)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhh
Confidence            3567888777766544433333333 334444444


No 441
>4L6R_A Soluble cytochrome b562 and Glucagon; Human glucagon receptor, diabetes, GPCR; 3.3A {Escherichia coli, Homo sapiens}
Probab=31.23  E-value=7.1  Score=38.95  Aligned_cols=34  Identities=24%  Similarity=0.451  Sum_probs=21.3  Template_Neff=10.500

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFE  678 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if~  678 (908)
                      ...|.+..++..++....+.-+++-.+-++..+.
T Consensus       205 ~~~C~~~~~~~~~~~las~~w~~~i~~~~~~~~~  238 (425)
T 4L6R_A          205 VAGCRVAAVFMQYGIVANYCWLLVEGLYLHNLLG  238 (425)
T ss_pred             ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            5678887777766665555555555555555444


No 442
>6KUW_A Alpha-2C adrenergic receptor; Alpha2c adrenergic receptor, antagonist, GPCR; HET: OLC, OLA, CLR, E33; 2.8A {Homo sapiens}
Probab=31.07  E-value=7.1  Score=39.70  Aligned_cols=17  Identities=12%  Similarity=-0.062  Sum_probs=10.6  Template_Neff=11.600

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..+...
T Consensus        92 ~~~~C~~~~~~~~~~~~  108 (496)
T 6KUW_A           92 GQWWCGVYLALDVLFCT  108 (496)
T ss_dssp             HHHHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHH
Confidence            36678887776554443


No 443
>4WW3_A BOG; Animals, Decapodiformes, Inositol 1, 4; HET: TWT, PC1, PLM, BOG, RET; 2.8A {Todarodes pacificus}
Probab=30.81  E-value=7.2  Score=36.86  Aligned_cols=17  Identities=12%  Similarity=0.038  Sum_probs=10.5  Template_Neff=12.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..++..
T Consensus        96 ~~~~c~~~~~~~~~~~~  112 (350)
T 4WW3_A           96 GFAACKVYGFIGGIFGF  112 (350)
T ss_dssp             HHHHHHHHHHHHHHHHH
T ss_pred             CchHHHHHHHHHHHHHH
Confidence            35678777766554443


No 444
>6J20_A Substance-P receptor,Endolysin (E.C. 3.2.1.17); GPCR, Complex, Antagonist, signalling protein; HET: GBQ; 2.7A {Homo sapiens}
Probab=30.61  E-value=7.3  Score=38.58  Aligned_cols=34  Identities=18%  Similarity=0.236  Sum_probs=17.0  Template_Neff=12.300

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALL-TKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~-~K~~ri~~if  677 (908)
                      ....|.+..++..+......-.++ .=.-|...+.
T Consensus       100 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~Ry~~i~  134 (441)
T 6J20_A          100 GLFYCKFHNFFPIAAVFASIWSMTAVAFDRYMAII  134 (441)
T ss_pred             hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhh
Confidence            356788877766544433333322 2334444444


No 445
>5YWY_A Prostaglandin E2 receptor EP4 subtype; G-protein coupled receptor, lipid mediator; HET: 7UR; 3.2A {Homo sapiens}
Probab=30.60  E-value=7.3  Score=36.50  Aligned_cols=34  Identities=12%  Similarity=0.138  Sum_probs=16.9  Template_Neff=12.600

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..+.+....-.++. -.-|...+.
T Consensus        88 ~~~~c~~~~~~~~~~~~~s~~~~~~is~~R~~~i~  122 (332)
T 5YWY_A           88 GQPLCEYSTFILLFFSLSRLSIICAMSVERYLAIN  122 (332)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888776665544433333322 233444443


No 446
>4JKV_A Soluble cytochrome b562, Smoothened homolog; Human smoothened receptor, antitumor agent; HET: 1KS, PG4, PGE, OLA, PEG, OLC; 2.45A {Escherichia coli}
Probab=30.35  E-value=7.5  Score=39.54  Aligned_cols=34  Identities=18%  Similarity=0.213  Sum_probs=19.3  Template_Neff=9.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if  677 (908)
                      ....|.+..++..+++...+.-+++-++-++..+
T Consensus       230 ~~~~C~~~~~l~~~~~las~~w~~~~a~~~~~~i  263 (475)
T 4JKV_A          230 ETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSF  263 (475)
T ss_dssp             SCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CchhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567887777766665555554444444444433


No 447
>4N4W_A Smoothened homolog; Human smoothened receptor, antitumor agent; HET: MAN, BMA, SNT, PG4, NAG, OLC; 2.8A {Homo sapiens, Shigella flexneri}
Probab=30.35  E-value=7.5  Score=39.54  Aligned_cols=34  Identities=18%  Similarity=0.213  Sum_probs=19.3  Template_Neff=9.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if  677 (908)
                      ....|.+..++..+++...+.-+++-++-++..+
T Consensus       230 ~~~~C~~~~~l~~~~~las~~w~~~~a~~~~~~i  263 (475)
T 4N4W_A          230 ETLSCVIIFVIVYYALMAGVVWFVVLTYAWHTSF  263 (475)
T ss_dssp             SCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGG
T ss_pred             CchhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567887777766665555554444444444433


No 448
>6FJ3_A Parathyroid hormone/parathyroid hormone-related peptide receptor; GPCR, cell signalling, 7TM, MEMBRANE; HET: FUC, OLA, NAG, MAN, YCM, PG4, HRG, BMA; 2.5A {Homo sapiens}
Probab=30.23  E-value=7.5  Score=41.02  Aligned_cols=33  Identities=12%  Similarity=0.126  Sum_probs=21.0  Template_Neff=10.000

Q NP_000836.2     646 IICSFRRVFLGLGMCFSYAALLTKTNRIHRIFE  678 (908)
Q Consensus       646 ~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if~  678 (908)
                      ..|.+..+++...+...|.=+++-.+-+|+.+.
T Consensus       214 ~~C~~~~~~~~y~~la~~~Wm~~e~~~l~~~i~  246 (602)
T 6FJ3_A          214 AGCRVAVTFFLYFLATNYYWIAVEGLYLHSLIF  246 (602)
T ss_dssp             -HHH-HHHH--HHHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            678888888777777777777777766666544


No 449
>5ZBH_A Neuropeptide Y receptor type 1,T4; G Protein-Coupled Receptor Neuropeptide Y; HET: 9AF; 3.0A {Homo sapiens}
Probab=29.80  E-value=7.7  Score=39.78  Aligned_cols=17  Identities=6%  Similarity=0.305  Sum_probs=10.6  Template_Neff=11.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..+.+.
T Consensus       118 ~~~~C~~~~~~~~~~~~  134 (527)
T 5ZBH_A          118 GEAMCKLNPFVQCVSIT  134 (527)
T ss_pred             hHHHHHHHHHHHHHHHH
Confidence            35678887766554443


No 450
>6NIY_R Adenosine receptor A1,Soluble cytochrome b562,Adenosine; GPCR, transmembrane, receptor, calcitonin, MEMBRANE;{Homo sapiens}
Probab=29.59  E-value=7.9  Score=39.32  Aligned_cols=27  Identities=19%  Similarity=0.292  Sum_probs=15.1  Template_Neff=10.300

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTKTN  671 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K~~  671 (908)
                      ...|.+..++..+.....+.-+++-++
T Consensus       216 ~~~C~~~~~l~~~~~~~s~~w~~~ia~  242 (474)
T 6NIY_R          216 PVSCKILHFFHQYMMACNYFWMLCEGI  242 (474)
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            567887776665554444444444443


No 451
>5XJM_A Type-2 angiotensin II receptor,Soluble cytochrome; class A GPCR, regulate human; 3.2A {Mus musculus}
Probab=29.03  E-value=8.1  Score=37.87  Aligned_cols=34  Identities=21%  Similarity=0.365  Sum_probs=17.6  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++..++.....-.+++ -.-|...+.
T Consensus        80 ~~~~C~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  114 (422)
T 5XJM_A           80 GPVMCKVFGSFLTLNMFASIFFITCMSVDRYQSVI  114 (422)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888877766554433333332 233444443


No 452
>6VMS_R Guanine nucleotide-binding protein G(i) subunit; Dopamine, Dopamine receptor, GPCR, G; HET: 08Y; 3.8A {Rattus norvegicus}
Probab=28.87  E-value=8.2  Score=38.63  Aligned_cols=16  Identities=13%  Similarity=0.044  Sum_probs=9.8  Template_Neff=11.300

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..+++.
T Consensus       245 ~~~C~~~~~~~~~~~~  260 (450)
T 6VMS_R          245 RIHCDIFVTLDVMMCT  260 (450)
T ss_dssp             TTHHHHHHHHHHHHHH
T ss_pred             hHHHHHHHHHHHHHHH
Confidence            5678777766554443


No 453
>6PS2_A Fusion protein of Beta-2 adrenergic; GPCR, COMPLEX-LCP method, SBDD, drug; HET: CLR, SO4, JTZ, OLB, OLA, OLC; 2.4A {Homo sapiens}
Probab=28.33  E-value=8.5  Score=39.39  Aligned_cols=34  Identities=18%  Similarity=0.134  Sum_probs=16.6  Template_Neff=10.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYA-ALLTKTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~-~l~~K~~ri~~if  677 (908)
                      ....|.+..++..++.....- .++.=.-|.+.+.
T Consensus       126 ~~~~C~~~~~l~~~~~~~s~~~~~~iai~Ry~ai~  160 (506)
T 6PS2_A          126 GNFWCEFWTSIDVLCVTASIWTLCVIAVDRYFAIT  160 (506)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHT
T ss_pred             hhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            356788777765544433222 2233334544443


No 454
>6PB0_R Corticotropin-releasing factor receptor 1, Urocortin; Corticotropin-releasing factor 1 receptor, urocortins1; HET: CLR, PLM; 3.0A {Homo sapiens}
Probab=28.25  E-value=8.6  Score=37.30  Aligned_cols=28  Identities=4%  Similarity=-0.014  Sum_probs=17.0  Template_Neff=11.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTN  671 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~  671 (908)
                      ....|.+..++...+....+..+++-.+
T Consensus       161 ~~~~C~~~~~~~~~~~~~s~~~l~~ia~  188 (375)
T 6PB0_R          161 NVGWCRLVTAAYNYFHVTNFFWMFGEGC  188 (375)
T ss_dssp             CCHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CchHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            3567888777766655555555555443


No 455
>3PDS_A Fusion protein Beta-2 adrenergic receptor/Lysozyme; GPCR, signaling, beta adrenergic agonist; HET: ERC, CLR, SO4; 3.5A {Homo sapiens,Enterobacteria phage T4,Homo sapiens}
Probab=28.08  E-value=8.7  Score=38.53  Aligned_cols=33  Identities=15%  Similarity=0.119  Sum_probs=16.1  Template_Neff=11.400

Q NP_000836.2     645 TIICSFRRVFLGLGMCF-SYAALLTKTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l-~~~~l~~K~~ri~~if  677 (908)
                      ...|.+..++..++... .+..++.=.-|.+.+.
T Consensus        79 ~~~c~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  112 (458)
T 3PDS_A           79 NFWCEFWTSIDVLCVTASIETLCVIAVDRYFAIT  112 (458)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHS
T ss_pred             cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            56787777665544332 2223333334544443


No 456
>5UEN_B Adenosine receptor A1,Soluble cytochrome b562,Adenosine; GPCR, transmembrane, receptor, adenosine, MEMBRANE; HET: OLA, DU1; 3.2A {Homo sapiens}
Probab=27.53  E-value=9  Score=37.51  Aligned_cols=16  Identities=6%  Similarity=-0.155  Sum_probs=9.6  Template_Neff=12.200

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..+.+.
T Consensus        78 ~~~C~~~~~~~~~~~~   93 (416)
T 5UEN_B           78 FHTCLMVACPVLILTQ   93 (416)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             cchhHHHHHHHHHHHH
Confidence            4578777766554443


No 457
>5ZBQ_A Neuropeptide Y Y1 receptor in; G Protein-Coupled Receptor, Receptor Inhibitor; HET: 9AO; 2.7A {Homo sapiens}
Probab=27.31  E-value=9.1  Score=39.21  Aligned_cols=20  Identities=10%  Similarity=0.287  Sum_probs=11.7  Template_Neff=11.500

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSY  663 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~  663 (908)
                      ....|.+..++..+++....
T Consensus       108 ~~~~C~~~~~~~~~~~~~s~  127 (525)
T 5ZBQ_A          108 GEAMCKLNPFVQCVSITVSI  127 (525)
T ss_pred             hHHHHHHHHHHHHHHHHHHH
Confidence            35678877766655544333


No 458
>6RNK_A Succinate receptor 1, Nanobody6; SUCNR1, GPR91, GPCR, G-Protein coupled; HET: KAZ, OLC; 1.94A {Rattus norvegicus}
Probab=27.26  E-value=9.1  Score=36.04  Aligned_cols=34  Identities=18%  Similarity=0.179  Sum_probs=16.7  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLT-KTNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~-K~~ri~~if  677 (908)
                      ....|.+..++...++....-.++. -.-|...+.
T Consensus        94 ~~~~c~~~~~~~~~~~~~s~~~~~~i~~~R~~~i~  128 (342)
T 6RNK_A           94 GDVLCISNRYVLHANLYTSILFLTFISIDRYLLMK  128 (342)
T ss_pred             chHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            3567877776665544433333332 233444443


No 459
>5UEN_A Adenosine receptor A1,Soluble cytochrome b562,Adenosine; GPCR, transmembrane, receptor, adenosine, MEMBRANE; HET: DU1, OLA; 3.2A {Homo sapiens}
Probab=27.12  E-value=9.2  Score=37.37  Aligned_cols=16  Identities=6%  Similarity=-0.155  Sum_probs=9.6  Template_Neff=12.300

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..++..
T Consensus        78 ~~~C~~~~~~~~~~~~   93 (416)
T 5UEN_A           78 FHTCLMVACPVLILTQ   93 (416)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             cchhHHHHHHHHHHHH
Confidence            4578777766554443


No 460
>6PB1_P Corticotropin-releasing factor receptor 2, Urocortin; Corticotropin-releasing factor 2 receptor, urocortins1; HET: CLR, PLM; 2.8A {Homo sapiens}
Probab=26.87  E-value=9.4  Score=37.30  Aligned_cols=33  Identities=6%  Similarity=0.185  Sum_probs=20.5  Template_Neff=10.700

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTNRIHRI  676 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~i  676 (908)
                      ....|.+..++...+....+..+++-.+-.|..
T Consensus       179 ~~~~C~~~~~~~~~~~~~s~~~l~~ia~~ry~~  211 (387)
T 6PB1_P          179 NEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTA  211 (387)
T ss_dssp             CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            457888887777666665555555555444433


No 461
>6OMM_R N-formyl peptide receptor 2, Peptide; Formyl peptide receptor 2/lipoxin A4; HET: PLM, CLR; 3.17A {Homo sapiens}
Probab=26.55  E-value=9.6  Score=36.23  Aligned_cols=16  Identities=6%  Similarity=0.468  Sum_probs=9.9  Template_Neff=12.500

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++..+++.
T Consensus       116 ~~~c~~~~~~~~~~~~  131 (363)
T 6OMM_R          116 WFLCKLIHIVVDINLF  131 (363)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHH
Confidence            5678777666554443


No 462
>5N2S_A Adenosine receptor A2a,Soluble cytochrome b562,Adenosine; G-PROTEIN-COUPLED RECEPTOR, INTEGRAL THERMOSTABILIZING MUTATIONS; HET: 8K8, SO4; 3.303A {Escherichia coli}
Probab=26.30  E-value=9.8  Score=37.63  Aligned_cols=15  Identities=7%  Similarity=-0.115  Sum_probs=8.7  Template_Neff=11.900

Q NP_000836.2     645 TIICSFRRVFLGLGM  659 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf  659 (908)
                      ...|.+..++..+.+
T Consensus       184 ~~~c~~~~~~~~~~~  198 (436)
T 5N2S_A          184 FHTCLMVACPVLILA  198 (436)
T ss_dssp             HHHHHHHHHHHHHHH
T ss_pred             hHHHHHhHHHHHHHH
Confidence            446777666655433


No 463
>5LWE_A C-C chemokine receptor type 9; Membrane protein; HET: CLR, 79K, MLI, OLA; 2.8A {Homo sapiens}
Probab=25.09  E-value=11  Score=35.31  Aligned_cols=20  Identities=10%  Similarity=0.283  Sum_probs=11.5  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSY  663 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~  663 (908)
                      ....|....++..+++....
T Consensus        93 ~~~~c~~~~~~~~~~~~~s~  112 (331)
T 5LWE_A           93 QTFMCKVVNSMYKMNFYSCV  112 (331)
T ss_dssp             -CHHHHHHHHHHHHHHHHHH
T ss_pred             chHHHHHHHHHHHHHHHHHH
Confidence            46678877766555444333


No 464
>5ZTY_A G protein coupled receptor, T4; GPCR, cell signaling, ligand design; HET: OLC, SO4, PG4, OLA, 9JU, PEG, EPE; 2.8A {Homo sapiens}
Probab=24.40  E-value=11  Score=38.32  Aligned_cols=20  Identities=15%  Similarity=0.295  Sum_probs=9.0  Template_Neff=10.800

Q NP_000836.2     585 VVPVFVAILGIIATTFVIVT  604 (908)
Q Consensus       585 ~~~~~~~~~~i~~~~~~~~~  604 (908)
                      ++..++.++|++.-+++++.
T Consensus        37 ~~~~i~~~~gl~gN~lvl~~   56 (500)
T 5ZTY_A           37 VLCTLLGLLSALENVAVLYL   56 (500)
T ss_pred             HHHHHHHHHHHHHHHHHHHH
Confidence            33444445555444444433


No 465
>2KSA_A Substance-P receptor, Substance P; Substance P, DMPC/CHAPS bicelle, Autodock; NMR {Homo sapiens}
Probab=23.57  E-value=12  Score=35.48  Aligned_cols=16  Identities=19%  Similarity=0.395  Sum_probs=9.5  Template_Neff=12.600

Q NP_000836.2     645 TIICSFRRVFLGLGMC  660 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~  660 (908)
                      ...|.+..++...++.
T Consensus       102 ~~~c~~~~~~~~~~~~  117 (364)
T 2KSA_A          102 LFYCKFHNFFPIAAVF  117 (364)
T ss_dssp             HHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHH
Confidence            5677776666554443


No 466
>5LWE_B C-C chemokine receptor type 9; Membrane protein; HET: 79K, OLA, MLI, CLR; 2.8A {Homo sapiens}
Probab=23.45  E-value=12  Score=34.90  Aligned_cols=18  Identities=11%  Similarity=0.333  Sum_probs=10.4  Template_Neff=12.400

Q NP_000836.2     644 DTIICSFRRVFLGLGMCF  661 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l  661 (908)
                      ....|.+..++..+++..
T Consensus        93 ~~~~c~~~~~~~~~~~~~  110 (331)
T 5LWE_B           93 QTFMCKVVNSMYKMNFYS  110 (331)
T ss_dssp             -CTTHHHHHHHHHHHHHH
T ss_pred             chhHHHHHHHHHHHHHHH
Confidence            456787776665544443


No 467
>5DHG_B Nociceptin receptor-Cytochrome b562 Chimera; Nociceptin/orphanin FQ peptide receptor, NOP; HET: DGV, OLA, OLC; 3.0A {Escherichia coli}
Probab=23.42  E-value=12  Score=36.65  Aligned_cols=34  Identities=18%  Similarity=0.097  Sum_probs=17.4  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+++...+-.++.- ..|...+.
T Consensus       193 ~~~~c~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  227 (424)
T 5DHG_B          193 GNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAIC  227 (424)
T ss_dssp             CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            35678877776655544433333332 33444443


No 468
>5DHH_B GPCR-BRIL Chimera; Nociceptin/orphanin FQ peptide receptor, NOP; HET: OLA, OLC, DGW; 3.004A {Homo sapiens}
Probab=23.42  E-value=12  Score=36.65  Aligned_cols=34  Identities=18%  Similarity=0.097  Sum_probs=17.4  Template_Neff=12.100

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTK-TNRIHRIF  677 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K-~~ri~~if  677 (908)
                      ....|.+..++..+++...+-.++.- ..|...+.
T Consensus       193 ~~~~c~~~~~~~~~~~~~s~~~~~~iai~R~~~i~  227 (424)
T 5DHH_B          193 GNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAIC  227 (424)
T ss_dssp             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
Confidence            35678877776655544433333332 33444443


No 469
>4DKL_A Mu-type opioid receptor, lysozyme chimera; G-protein coupled receptor, 7 transmembrane; HET: SO4, CLR, MPG, BF0, 1PE; 2.8A {Mus musculus, Enterobacteria phage T4}
Probab=20.35  E-value=15  Score=36.47  Aligned_cols=17  Identities=18%  Similarity=0.227  Sum_probs=10.1  Template_Neff=11.900

Q NP_000836.2     644 DTIICSFRRVFLGLGMC  660 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~  660 (908)
                      ....|.+..++..+++.
T Consensus        85 ~~~~C~~~~~~~~~~~~  101 (464)
T 4DKL_A           85 GNILCKIVISIDYYNMF  101 (464)
T ss_dssp             CSHHHHHHHHHHHHHHH
T ss_pred             cchHHHHHHHHHHHHHH
Confidence            35678777766554433


No 470
>5NX2_A Glucagon-like peptide 1 receptor, truncated; 7TM, GPCR, signalling protein, membrane; HET: SOG, 9DQ, 9DZ, 9DT, 9DW, 9DK, NAG; 3.7A {Homo sapiens}
Probab=20.13  E-value=16  Score=36.14  Aligned_cols=33  Identities=15%  Similarity=0.316  Sum_probs=19.8  Template_Neff=10.600

Q NP_000836.2     645 TIICSFRRVFLGLGMCFSYAALLTKTNRIHRIF  677 (908)
Q Consensus       645 ~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if  677 (908)
                      +..|.+..++........+.-+++-.+-+++..
T Consensus       204 ~~~C~~~~~~~~~~~las~~w~~~~~~~~~~~i  236 (422)
T 5NX2_A          204 SLSCRLVFLFMQYCVAANYYWLLVEGVYLYTLL  236 (422)
T ss_dssp             SHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
T ss_pred             cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            478888777766665555555555554444443


No 471
>6LN2_A Glucagon-like peptide 1 receptor,Rubredoxin,Glucagon-like peptide; Full length Human GLP1 receptor; HET: 97Y, NAG; 3.2A {Homo sapiens}
Probab=20.07  E-value=16  Score=36.87  Aligned_cols=35  Identities=14%  Similarity=0.264  Sum_probs=21.7  Template_Neff=8.200

Q NP_000836.2     644 DTIICSFRRVFLGLGMCFSYAALLTKTNRIHRIFE  678 (908)
Q Consensus       644 ~~~~C~~~~~~~~~gf~l~~~~l~~K~~ri~~if~  678 (908)
                      ....|.+..++....+...+.-+++-.+-+++.+.
T Consensus       199 ~~~~C~~~~~l~~y~~las~~W~~~~a~~l~~~i~  233 (469)
T 6LN2_A          199 DSLACRLVFLLCQYCVAANYYWLLVEGVYLYTLLA  233 (469)
T ss_dssp             HHTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
T ss_pred             CcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
Confidence            35778888777766666666666555555444443