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comparison test-data/model/ACE2_HUMAN.hhr @ 0:64cb5fab9c60 draft

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"planemo upload commit 6158473dbced09024b0a805a7df2c93d47705d87"
author guerler
date Tue, 23 Mar 2021 13:57:37 +0000
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-1:000000000000 0:64cb5fab9c60
1 Query sp|Q9BYF1|ACE2_HUMAN Angiotensin-converting enzyme 2 OS=Homo sapiens (Human) OX=9606 GN=ACE2 PE=1 SV=2
2 Match_columns 805
3 No_of_seqs 1 out of 1
4 Neff 1
5 Searched_HMMs 82491
6 Date Sat Oct 10 23:55:36 2020
7 Command hhsearch -e 0.001 -i /galaxy-repl/main/files/046/047/dataset_46047478.dat -d hhdb -o /galaxy-repl/main/files/046/091/dataset_46091622.dat
8
9 No Hit Prob E-value P-value Score SS Cols Query HMM Template HMM
10 1 6M18_B Sodium-dependent neutra 100.0 4E-194 5E-199 1504.8 0.0 804 2-805 3-814 (814)
11 2 1R42_A angiotensin I convertin 100.0 3.4E-78 4.2E-83 582.0 0.0 615 1-615 1-615 (615)
12 3 6LZG_A Angiotensin-converting 100.0 5.4E-74 6.6E-79 545.9 0.0 597 19-615 1-597 (597)
13 4 3D0I_B Crystal structure of sp 100.0 1.2E-73 1.5E-78 545.2 0.0 596 20-615 2-597 (597)
14 5 5AMB_A ANGIOTENSIN-CONVERTING 100.0 1.2E-69 1.5E-74 524.2 0.0 595 20-625 12-614 (629)
15 6 6H5W_A Angiotensin-converting 100.0 4.4E-61 5.4E-66 455.7 0.0 579 22-613 5-588 (591)
16 7 6S1Y_A Angiotensin-converting 100.0 4.6E-59 5.5E-64 450.3 0.0 579 21-610 11-600 (621)
17 8 4CA5_A ANGIOTENSIN-CONVERTING 100.0 3.9E-58 4.7E-63 435.5 0.0 578 22-612 5-587 (589)
18 9 5A2R_A ANGIOTENSIN-CONVERTING 100.0 2.8E-56 3.4E-61 425.1 0.0 579 22-611 5-594 (598)
19 10 4ASR_A ANGIOTENSIN-CONVERTING 100.0 2.9E-56 3.5E-61 426.4 0.0 578 22-611 6-595 (598)
20 11 4CA7_A ANGIOTENSIN-CONVERTING 100.0 3.2E-56 3.9E-61 426.0 0.0 578 22-611 6-595 (598)
21 12 2C6F_A ANGIOTENSIN-CONVERTING 100.0 2.3E-52 2.7E-57 400.7 0.0 579 22-611 14-599 (612)
22 13 5GIV_E Carboxypeptidase; M32 c 100.0 4.3E-52 5.2E-57 399.6 0.0 474 19-597 3-502 (503)
23 14 5GIV_F Carboxypeptidase; M32 c 100.0 4.3E-52 5.2E-57 399.6 0.0 474 19-597 3-502 (503)
24 15 3HQ2_B Bacillus subtilis M32 c 100.0 1.1E-47 1.3E-52 361.2 0.0 473 22-597 3-500 (501)
25 16 1K9X_B m32 carboxypeptidase; H 100.0 1.1E-46 1.3E-51 357.8 0.0 470 20-593 4-499 (499)
26 17 1KA2_A M32 carboxypeptidase; H 100.0 1.1E-46 1.3E-51 357.8 0.0 470 20-593 4-499 (499)
27 18 5E3X_A Thermostable carboxypep 100.0 2.4E-46 2.9E-51 356.7 0.0 456 27-597 2-486 (489)
28 19 3HOA_A Thermostable carboxypep 100.0 1.1E-45 1.3E-50 356.9 0.0 468 22-594 3-507 (509)
29 20 3DWC_B Metallocarboxypeptidase 100.0 2E-44 2.4E-49 343.9 0.0 459 23-593 3-501 (505)
30 21 5WVU_C Thermostable carboxypep 100.0 8.4E-44 1E-48 344.0 0.0 469 22-595 3-508 (510)
31 22 3SKS_A Putative Oligoendopepti 100.0 1.7E-38 2.1E-43 300.7 0.0 506 22-600 36-564 (567)
32 23 3AHN_A Oligopeptidase; HYDROLA 100.0 2.6E-38 3.2E-43 299.3 0.0 505 22-601 33-562 (564)
33 24 2QR4_A Peptidase M3B, oligoend 100.0 2E-33 2.4E-38 267.6 0.0 506 23-603 34-578 (587)
34 25 2O36_A Thimet oligopeptidase ( 99.9 5E-30 6.1E-35 254.5 0.0 518 26-588 47-660 (674)
35 26 3CE2_A Crystal structure of pu 99.9 1.1E-29 1.4E-34 244.3 0.0 507 23-601 67-609 (618)
36 27 2O3E_A Neurolysin (E.C.3.4.24. 99.9 9.4E-29 1.1E-33 246.4 0.0 515 31-588 68-676 (678)
37 28 5LV0_A Neurolysin, mitochondri 99.9 6.2E-28 7.6E-33 240.2 0.0 504 41-589 83-682 (686)
38 29 1S4B_P Thimet oligopeptidase ( 99.9 1.6E-27 2E-32 236.8 0.0 516 26-588 47-660 (674)
39 30 5L44_A K-26 dipeptidyl carboxy 99.8 4.9E-23 6E-28 205.4 0.0 512 28-589 76-681 (683)
40 31 5L43_B K-26 dipeptidyl carboxy 99.8 4.9E-23 6E-28 205.4 0.0 512 28-589 76-681 (683)
41 32 1Y79_1 Peptidyl-Dipeptidase Dc 99.4 4.5E-17 5.4E-22 163.2 0.0 501 41-588 70-676 (680)
42 33 4KA7_A Oligopeptidase A, short 99.4 5.8E-17 7.1E-22 163.7 0.0 407 144-589 239-706 (714)
43 34 2KNC_B Integrin alpha-IIb, Int 92.7 0.036 4.4E-07 45.3 0.0 31 733-763 2-32 (79)
44 35 2L8S_A Integrin alpha-1; Integ 87.6 0.29 3.5E-06 40.2 0.0 43 736-778 4-48 (54)
45 36 2N2A_B Receptor tyrosine-prote 86.5 0.38 4.6E-06 38.4 0.0 30 742-771 9-38 (58)
46 37 2KNC_A Integrin alpha-IIb, Int 85.7 0.45 5.4E-06 38.7 0.0 40 735-774 6-47 (54)
47 38 2M3E_A Integrin alpha-L; integ 85.4 0.48 5.8E-06 38.2 0.0 39 736-774 7-47 (50)
48 39 6J8H_C Sodium channel subunit 84.3 0.6 7.2E-06 37.2 0.0 8 591-598 64-71 (215)
49 40 2N9Y_B Integrin alpha-IIb, Int 84.0 0.63 7.7E-06 35.0 0.0 30 737-766 5-34 (43)
50 41 6JXR_n T-cell surface glycopro 83.4 0.7 8.5E-06 38.0 0.0 7 591-597 154-160 (291)
51 42 2K9J_A Integrin alpha-IIb ligh 83.0 0.74 9E-06 35.9 0.0 39 732-770 1-41 (42)
52 43 2N5S_A Epidermal growth factor 82.7 0.79 9.6E-06 34.0 0.0 10 744-753 8-17 (54)
53 44 4UM8_D INTEGRIN ALPHA-V, INTEG 80.8 1 1.3E-05 49.0 0.0 25 738-762 705-729 (788)
54 45 4UM8_B INTEGRIN ALPHA-V, INTEG 78.7 1.4 1.7E-05 48.1 0.0 25 738-762 705-729 (788)
55 46 1AFO_A GLYCOPHORIN A; INTEGRAL 75.9 1.9 2.3E-05 35.5 0.0 37 732-771 4-40 (40)
56 47 6A69_B Plasma membrane calcium 75.9 1.9 2.3E-05 35.7 0.0 15 742-756 224-238 (282)
57 48 6AGF_B Sodium channel protein 75.3 2 2.5E-05 35.7 0.0 22 773-795 192-213 (218)
58 49 6J8J_B Sodium channel subunit 75.3 2 2.5E-05 35.7 0.0 22 773-795 192-213 (218)
59 50 6C14_A Protocadherin-15, LHFPL 74.5 2.2 2.7E-05 40.6 0.0 23 738-760 238-260 (337)
60 51 6UJB_B Integrin alpha-V, Integ 73.3 2.5 3E-05 45.8 0.0 25 738-762 637-661 (727)
61 52 6UJA_B Integrin alpha-V, Integ 73.3 2.5 3E-05 45.8 0.0 25 738-762 637-661 (727)
62 53 2M20_A Epidermal growth factor 72.7 2.6 3.2E-05 32.9 0.0 10 744-753 5-14 (60)
63 54 5OR7_C Capsid protein, CMRF35- 72.6 2.7 3.2E-05 38.5 0.0 6 592-597 52-57 (330)
64 55 2MFR_A Insulin receptor (E.C.2 69.0 3.6 4.4E-05 33.9 0.0 38 740-779 15-52 (57)
65 56 4U0Q_B Plasmodium falciparum R 67.3 4.2 5.1E-05 33.8 0.0 13 744-756 211-223 (269)
66 57 5A2F_A CD166 ANTIGEN; CELL ADH 63.7 5.5 6.7E-05 38.7 0.0 11 589-599 442-452 (583)
67 58 2KLU_A T-cell surface glycopro 59.8 7.3 8.8E-05 30.3 0.0 9 744-752 12-20 (70)
68 59 6ENY_C Beta-2-microglobulin, T 58.0 8.2 9.9E-05 37.8 0.0 9 539-547 248-256 (428)
69 60 1S7Q_A H-2 class I histocompat 57.9 8.2 0.0001 37.5 0.0 11 742-752 285-295 (348)
70 61 1S7S_A H-2 class I histocompat 57.9 8.2 0.0001 37.5 0.0 11 742-752 285-295 (348)
71 62 2WY3_A MHC CLASS I POLYPEPTIDE 57.3 8.6 0.0001 35.8 0.0 9 591-599 214-222 (319)
72 63 6JXR_f T-cell surface glycopro 55.1 9.8 0.00012 32.9 0.0 14 741-754 130-143 (207)
73 64 3LB6_C Interleukin-13, Interle 54.8 10 0.00012 33.3 0.0 18 670-687 293-310 (380)
74 65 3LB6_D Interleukin-13, Interle 54.8 10 0.00012 33.3 0.0 18 670-687 293-310 (380)
75 66 6FGB_A IgG receptor FcRn large 49.5 14 0.00017 35.5 0.0 10 776-785 311-320 (342)
76 67 4NKQ_B Cytokine receptor commo 46.9 16 0.0002 32.2 0.0 18 670-687 186-203 (305)
77 68 6JXR_g T-cell surface glycopro 43.8 20 0.00024 29.7 0.0 10 743-752 117-126 (182)
78 69 5EH6_A Glycophorin-A; Receptor 43.3 20 0.00025 28.5 0.0 24 741-766 4-27 (30)
79 70 5EH4_C Glycophorin-A; Receptor 43.3 20 0.00025 28.5 0.0 24 741-766 4-27 (30)
80 71 2XQ2_A SODIUM/GLUCOSE COTRANSP 39.8 25 0.0003 38.0 0.0 33 739-773 548-580 (593)
81 72 2RDD_B Acriflavine resistance 39.2 26 0.00031 26.1 0.0 20 756-775 12-31 (37)
82 73 6CPL_A HLA class II histocompa 39.1 26 0.00031 31.3 0.0 8 591-598 118-125 (229)
83 74 6EJ2_A Beta-secretase 1 (E.C.3 38.0 28 0.00034 35.2 0.0 15 736-750 452-466 (501)
84 75 6ENY_F Beta-2-microglobulin, T 37.9 28 0.00034 33.9 0.0 6 592-597 215-220 (341)
85 76 5XTH_0 NADH dehydrogenase [ubi 37.1 29 0.00035 33.4 0.0 32 732-763 65-96 (144)
86 77 5B1A_D Cytochrome c oxidase su 33.8 36 0.00044 33.1 0.0 32 732-763 68-99 (147)
87 78 6PY2_A HLA class II histocompa 33.3 37 0.00045 31.4 0.0 9 591-599 143-151 (254)
88 79 6GJE_A Protein amnionless, Cub 33.2 37 0.00045 37.8 0.0 18 783-800 399-416 (453)
89 80 6C13_A Protocadherin-15; PCDH1 32.9 38 0.00046 35.0 0.0 13 693-705 508-520 (660)
90 81 5DJQ_P Cbb3-type cytochrome c 32.8 38 0.00046 27.7 0.0 24 748-771 7-35 (36)
91 82 1CD1_A CD1; CD1, IMMUNOLOGY, M 32.5 39 0.00047 31.8 0.0 7 592-598 217-223 (315)
92 83 6AT5_A HLA class I histocompat 29.9 46 0.00056 33.0 0.0 8 591-598 238-245 (362)
93 84 4JIX_A Uncharacterized protein 28.2 51 0.00062 27.7 0.0 41 371-421 68-108 (112)
94 85 4JIX_B Projannalysin; Hydrolas 28.2 51 0.00062 27.7 0.0 41 371-421 68-108 (112)
95 86 6IDF_E Nicastrin, Presenilin-1 27.6 53 0.00065 31.8 0.0 16 733-748 9-24 (129)
96 87 6IVA_D Oxaloacetate decarboxyl 26.5 58 0.0007 29.7 0.0 27 738-764 31-57 (104)
97 88 6IWW_B Oxaloacetate decarboxyl 26.5 58 0.0007 29.7 0.0 27 738-764 31-57 (104)
98 89 6BRJ_A Epithelial discoidin do 25.3 63 0.00076 37.1 0.0 7 602-608 254-260 (876)
99 90 3EHB_B Cytochrome c oxidase su 25.2 63 0.00076 33.8 0.0 47 725-771 47-93 (298)
100 91 6PY2_B HLA class II histocompa 24.3 67 0.00082 30.1 0.0 11 745-755 235-245 (261)
101 92 1Q5B_C EP-cadherin, ectodomain 24.1 68 0.00082 35.0 0.0 12 155-166 149-160 (880)
102 93 2JO1_A Phospholemman; FXYD1, N 23.9 69 0.00084 29.3 0.0 30 747-776 20-49 (72)
103 94 2KV5_A Putative uncharacterize 23.5 71 0.00086 25.4 0.0 27 745-771 4-31 (33)
104 95 6BSD_A Epithelial discoidin do 23.3 72 0.00088 36.6 0.0 7 602-608 254-260 (876)
105 96 6KOE_F AA3-600 quinol oxidase 22.6 76 0.00092 33.7 0.0 40 732-771 11-50 (296)
106 97 6KOB_B AA3-600 quinol oxidase 22.6 76 0.00092 33.7 0.0 40 732-771 11-50 (296)
107 98 1Q90_G Apocytochrome f, Cytoch 22.4 78 0.00094 26.3 0.0 29 744-772 5-33 (37)
108 99 2GSM_B Cytochrome c oxidase su 21.9 80 0.00097 31.8 0.0 6 721-726 4-9 (262)
109 100 3HB3_B Cytochrome c oxidase su 21.5 83 0.001 32.9 0.0 47 725-772 47-94 (298)
110 101 5X5V_A GD; herpes simplex viru 20.1 93 0.0011 35.6 0.0 28 742-769 355-382 (402)
111
112 No 1
113 >6M18_B Sodium-dependent neutral amino acid transporter; ACE2-B0AT1 complex, MEMBRANE PROTEIN; HET: 3PH, NAG; 2.9A {Homo sapiens}
114 Probab=100.00 E-value=3.9e-194 Score=1504.77 Aligned_cols=804 Identities=100% Similarity=1.532 Sum_probs=737.6 Template_Neff=7.700
115
116 Q sp|Q9BYF1|ACE2 2 SSSSWLLLSLVAVTAA--------QSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFL 73 (805)
117 Q Consensus 2 sssswlllslvavtaa--------qstieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsafl 73 (805)
118 +.+.|++++||+++++ +++.|++|++||++++.+++++.+++++|+|+|+||+|+++.+.++.+..+|++|+
119 T Consensus 3 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~e~~a~~~L~~~d~~~~~l~~~~~~A~w~y~tn~t~e~~~~~~ea~~~ls~f~ 82 (814)
120 T 6M18_B 3 SSSSWLLLSLVAVTAAWSHPQFEKQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFL 82 (814)
121 T ss_dssp ---------------------------CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCSTTHHHHHHHHHHHHHHH
122 T ss_pred hHHHHHHHHHHHHHHhcCCcccCCCCCcHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHH
123 Confidence 4678999999999999 99999999999999999999999999999999999999999999999999999999
124
125
126 Q sp|Q9BYF1|ACE2 74 KEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMA 153 (805)
127 Q Consensus 74 keqstlaqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneima 153 (805)
128 ++.++.++.|+++.+++-..|.||+.+++.|...|++++.++++.+++.|+++|+++.+|.+++|.+|+.++|++..+|+
129 T Consensus 83 ~~~~~~~~~~~~~~~~d~~~kr~L~~l~~~~~~~Ls~~~~~~l~~~~~~m~~~ys~~~v~~~~~p~~~~~L~~~l~~il~ 162 (814)
130 T 6M18_B 83 KEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMA 162 (814)
131 T ss_dssp HHHHHHGGGSCTTSCCCHHHHHHHHHHHCCGGGGSCTTHHHHHHHHHHHHHHHHHHCEEECSSCTTCEEECCCCCHHHHH
132 T ss_pred HHHHHHHhhcChhhcCCHHHHHHHHHHHHcCccCCCHHHHHHHHHHHHHHHHHHHcCCcCCCCCCCcccccCHHHHHHHh
133 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
134
135
136 Q sp|Q9BYF1|ACE2 154 NSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEI 233 (805)
137 Q Consensus 154 nsldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeei 233 (805)
138 ++-|+.+|.++|+.|++.+++.++|+|+++|-++|++|+.+.|+||+|||+.+|+.++.++|||++.++.+.++..+++|
139 T Consensus 163 ~s~D~~~R~~aw~a~~~~~~~~~~~~l~~lv~lrne~Akl~Gy~sy~d~~l~~~e~~~~~~~~ys~~~~~~~Le~L~~~i 242 (814)
140 T 6M18_B 163 NSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEI 242 (814)
141 T ss_dssp HCCCHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHTTTCSSHHHHHGGGGCBCSSSSCCBCSSHHHHHHHHHHHHH
142 T ss_pred cCCCHHHHHHHHHHHHhHhcHHhHHHHHHHHHHHHHHHHhCCCCCHHHHHHhhhccCCCCCCCCCHHHHHHHHHHHHHHH
143 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
144
145
146 Q sp|Q9BYF1|ACE2 234 KPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEK 313 (805)
147 Q Consensus 234 kplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaek 313 (805)
148 +|+|+.||+|+|.++...|++.|++-+++|+|+||+|||++|+++|.+++||.+++++|+|++|+.+.|...++|+.+++
149 T Consensus 243 ~ply~~l~ayvr~kl~~~yg~~i~~~~~iPahllg~~~~~~w~~~y~~~~p~~~~~~~dv~~~~~~~~~t~~~~~~~a~~ 322 (814)
150 T 6M18_B 243 KPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEK 322 (814)
151 T ss_dssp HHHHHHHHHHHHHHHTTTSTTSSCTTBCEEGGGSSSSSSSCCGGGHHHHCSSTTSCCCCCTTHHHHTTCCTTHHHHHHHH
152 T ss_pred HHHHHHHHHHHHHHHHHHCcccCCCCCCCcHHHhHhhhHHHHHHhhcccCCCCCCCCCCCcHHHHhcCCCHHHHHHHHHH
153 Confidence 99999999999999999888777888999999999999999999999999999999999999999999999999999999
154
155
156 Q sp|Q9BYF1|ACE2 314 FFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLR 393 (805)
157 Q Consensus 314 ffvsvglpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllr 393 (805)
158 ||.++|++.|+++||++++++.|+.-..++|||++||.+.+|+||+||++++|+||+|.||||||++|.|.|..||++.|
159 T Consensus 323 ~f~~lgl~~~~~~fw~~s~~~r~~K~~~~~C~~~a~d~~~~d~rI~~~~~~~~~d~~tl~HE~GHa~h~~~~~~qp~~~~ 402 (814)
160 T 6M18_B 323 FFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLR 402 (814)
161 T ss_dssp HHHHTTCCCCCSSTTTSCBCSCCCSSCCCCCSCEEEECSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHTTSTTSCGGGC
162 T ss_pred HHHhcCCCCCCCCcccHHhccCCCCCCCCCcCchHhcCCCCCeEEEeecCCCHHHHHHHHHHHHHHHHHHHhccCCchhc
163 Confidence 99999999999999999999999988899999999999889999999999999999999999999999999999999999
164
165
166 Q sp|Q9BYF1|ACE2 394 NGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQW 473 (805)
167 Q Consensus 394 nganegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqw 473 (805)
168 .|++.+||||++++|++++.+|+||+++|++.++++++.+.+||+|++++|++++++||.+++++|||.+|.|++++++|
169 T Consensus 403 ~~a~~~f~Eavsel~el~~~~p~~L~~~~ll~~~~~~~~~~~in~ll~~aL~~l~~lp~~~~~d~~r~~~f~g~i~~~~l 482 (814)
170 T 6M18_B 403 NGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQW 482 (814)
171 T ss_dssp SCSSTTSHHHHHHHHHHHSSSHHHHHHHTCSCSSCCCCTTHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHTSSCGGGH
172 T ss_pred cCCChHHHHHHHHHHHHHhhCHHHHHHccCcCCCCCCCcHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHhcCCCCHHHH
173 Confidence 99999999999999999999999999999999988888899999999999999999999999999999999999999999
174
175
176 Q sp|Q9BYF1|ACE2 474 MKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQK 553 (805)
177 Q Consensus 474 mkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqk 553 (805)
178 ++.||++.++..|++.|+++++++|||++.+|+.+++.+++|++.++++||+.+++|+.+.|+||||+||+++++++|++
179 T Consensus 483 n~~w~el~~~y~Gv~~p~~~~~~~~d~~~~~Hi~~~~~Yy~Y~~s~i~a~qi~~~l~~~~~~~~pl~~c~~~~s~~ag~~ 562 (814)
180 T 6M18_B 483 MKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQK 562 (814)
181 T ss_dssp HHHHHHHCCCCCCEECSSCCCTTCCGGGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCTTHHHH
182 T ss_pred HHHHHHHHHHHcCCCCCCCCCccCCCHHHHhhhhcCcchHHHHHHHHHHHHHHHHHHHHcccCCCchhCCCCCCHHHHHH
183 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
184
185
186 Q sp|Q9BYF1|ACE2 554 LFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAY 633 (805)
187 Q Consensus 554 lfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyadqsikvrislksalgdkay 633 (805)
188 |.+||+.|.|.||+-+++.+.|...+++.|+++||+||.+||+.+|++..+||.++|+||.+++||||||||+||||+||
189 T Consensus 563 l~~lL~~G~S~~~~ell~~~~G~~~~s~~~ll~yf~pL~~wL~~~n~~~~~gw~~~~~~~~~~~~~~~~~~~~~~~~~~~ 642 (814)
190 T 6M18_B 563 LFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAY 642 (814)
191 T ss_dssp HHHHHTTTTSSCHHHHHHTTTSCSSCCSHHHHHHTHHHHHHHHHHTSSSCCSCBTTCCTTSSSCEEEEECHHHHTSSSCC
192 T ss_pred HHHHHhcCCCCCHHHHHHHHHCCCCCCcHHHHHhHHHHHHHHHHhccCCCCCCCCCCCCCCCCcceeEEEcchhcCcccc
193 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
194
195
196 Q sp|Q9BYF1|ACE2 634 EWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRIND 713 (805)
197 Q Consensus 634 ewndnemylfrssvayamrqyflkvknqmilfgeedvrvanlkprisfnffvtapknvsdiiprtevekairmsrsrind 713 (805)
198 +||+||||||||++|||||+||.++|+|.+.|..+||.|.|.+|||||.|+||.|.|+|++||+.|||+||||||.|||+
199 T Consensus 643 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 722 (814)
200 T 6M18_B 643 EWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRIND 722 (814)
201 T ss_dssp CCCHHHHHHHHHHHHHHHHHHHHHTSCCCCCCCGGGEEEECCCTTSEEEEEEEETTEEEEECCHHHHHHHHHHTHHHHHH
202 T ss_pred cCChhhHHHHHHHHHHHHHHHHHHHccceeecccccEEEecCCCcEEEEEEEecCCCccccCCHHHHHHHHHhchhhhhh
203 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
204
205
206 Q sp|Q9BYF1|ACE2 714 AFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNP 793 (805)
207 Q Consensus 714 afrlndnsleflgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkknkarsgenpyasidiskgennp 793 (805)
208 ||+|+|++|||+||+|||+||.+|||.|||||||||||++||||++||++|||+||||+|+++++|||+++|+++|++||
209 T Consensus 723 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 802 (814)
210 T 6M18_B 723 AFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNP 802 (814)
211 T ss_dssp HHTCCSSSEECSSCCCCCCCCCCCSSCTHHHHHHHHHHHHHHHHHHHHTTTTTTC-------------------------
212 T ss_pred hhhcCCCceeecccCCCCCCCCCCCcchHHHHHHHHHHHHHHHHHHHHHhChhhHHHHccccCCCCCCccccccCCccCc
213 Confidence 99999999999999999999999999999999999999999999999999999999999999899999999999999999
214
215
216 Q sp|Q9BYF1|ACE2 794 GFQNTDDVQTSF 805 (805)
217 Q Consensus 794 gfqntddvqtsf 805 (805)
218 |||++||+||||
219 T Consensus 803 ~~~~~~~~~~~~ 814 (814)
220 T 6M18_B 803 GFQNTDDVQTSF 814 (814)
221 T ss_dssp ------------
222 T ss_pred ccCCCcccccCC
223 Confidence 999999999998
224
225
226 No 2
227 >1R42_A angiotensin I converting enzyme 2; zinc metallopeptidase domain, collectrin homology; HET: NAG; 2.2A {Homo sapiens} SCOP: d.92.1.5
228 Probab=100.00 E-value=3.4e-78 Score=581.98 Aligned_cols=615 Identities=100% Similarity=1.557 Sum_probs=553.7 Template_Neff=10.000
229
230 Q sp|Q9BYF1|ACE2 1 MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLA 80 (805)
231 Q Consensus 1 msssswlllslvavtaaqstieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstla 80 (805)
232 |++++|+|++||+++++.+..++.+.+++++++.+...+....+++.|.+.++.+++..+....+..+.+.++.+..+..
233 T Consensus 1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~ 80 (615)
234 T 1R42_A 1 MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLA 80 (615)
235 T ss_dssp ------------------CCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHTTT
236 T ss_pred ChhHHHHHHHHHHHHhcCCCcHHHHHHHHHHHHHHHHHHHhHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHH
237 Confidence 78999999999999999999999999999999999999999999999999999999999988889999999999999988
238
239
240 Q sp|Q9BYF1|ACE2 81 QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE 160 (805)
241 Q Consensus 81 qmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldyne 160 (805)
242 ..|.+..+.+-..+-+|+.+...+...|+++..++++..++.|...|++..+|.++.|.+|+.+.|.+..+|+++-|...
243 T Consensus 81 ~~~~~~~~~~~~~~~~l~~~~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~ 160 (615)
244 T 1R42_A 81 QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE 160 (615)
245 T ss_dssp TTSCSTTCCCHHHHHHHHHHTCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEEETTEEEEEEETTTBHHHHHHHCCCHHH
246 T ss_pred hhCChhhcCCHHHHHHHHHHHhcCccCCCHHHHHHHHHHHHHHHHHHhcCCccCCCCCCcccccChhHHHHHhcCCCHHH
247 Confidence 88887766666777788877777777888888888889999999999999999888888899888999999999999999
248
249
250 Q sp|Q9BYF1|ACE2 161 RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL 240 (805)
251 Q Consensus 161 rlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehl 240 (805)
252 |-.+|++|+...++.+.+++.+.+-+++++|+...|++|.|||..++++++++++||+..++.+.++..++.++|+|+.+
253 T Consensus 161 R~~~~~~~~~~~~~~~~~~l~~lv~lr~~~A~~~Gy~~~~~~~l~~~~~~~~~~~~y~~~~~~~~l~~l~~~v~p~~~~~ 240 (615)
254 T 1R42_A 161 RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL 240 (615)
255 T ss_dssp HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTTCBCSCTTTCBCSHHHHHHHHHHHHHHHHHHHHH
256 T ss_pred HHHHHHHHHHHhhHHhHHHHHHHHHHHHHHHHHCCCCCHHHHHHHhhccCCCCCCCCChhHHHHHHHHHHHHHHHHHHHH
257 Confidence 99999999998889999999999999999999999999999999999999999999999999999999999999999999
258
259
260 Q sp|Q9BYF1|ACE2 241 HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL 320 (805)
261 Q Consensus 241 hayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvgl 320 (805)
262 |+|+|.++...|+.-+++-+..|+|++|.||+..|+.+|....|+.+.+..+++..++.+.|..+++++.++++|-++|+
263 T Consensus 241 ~~~~~~~~~~~~~~~~~~~~l~p~d~~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~ 320 (615)
264 T 1R42_A 241 HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL 320 (615)
265 T ss_dssp HHHHHHHHHHHSTTTSCTTBCEEGGGSSSSSCSCCGGGHHHHCTTTTSCCCCCTTTTGGGTCCHHHHHHHHHHHHHTTTC
266 T ss_pred HHHHHHHHHHHCccCCCCCCCccHHHccccchhcchhhHhccCCCCCCCCCCCcHHHHHCCCCHHHHHHHHHHHHHHcCC
267 Confidence 99999987766664445567889999999999999999999999999988999999999999999999999999999999
268
269
270 Q sp|Q9BYF1|ACE2 321 PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF 400 (805)
271 Q Consensus 321 pnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegf 400 (805)
272 ..++..+|.++++..+|....+.|+|.+|+.+.++.||++|...+.+|+.|.+||+||..|.+.+..||++.+.+++.+|
273 T Consensus 321 ~~~~~~~w~~~~~~r~~K~~~~~c~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~ 400 (615)
274 T 1R42_A 321 PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF 400 (615)
275 T ss_dssp CCCCTTHHHHCBCSCCCTTCCCCCSCEEEEEETTEEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSTTH
276 T ss_pred ccCCcchhhhhccCCCCCCCCCccccchhcCCCCceEEEecCCCCHHHHHHHHHHHHHHHHHHHhccCCchHcCCCChHH
277 Confidence 99999999999998888877899999999887789999999999999999999999999999999899999998899999
278
279
280 Q sp|Q9BYF1|ACE2 401 HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM 480 (805)
281 Q Consensus 401 heavgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwem 480 (805)
282 +|+++++|+..+.+|.+|+.++++....+...+.+++.++++++..+..+|+.++++.|+|.+|.|+++.+++-+.||+.
283 T Consensus 401 ~E~~s~~~e~~~~~~~~l~~~~~~~~~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~~~~~~~~l 480 (615)
284 T 1R42_A 401 HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM 480 (615)
285 T ss_dssp HHHHHHHHHHHHHSHHHHHHTTSSCTTSCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTCSCGGGHHHHHHHH
286 T ss_pred HHHHHHHHHHHhcCHHHHHHcCCCCcccCCCcHHHHHHHHHHHHHHHhhccHHHHHHHHHHHHHcCCCCHHHHHHHHHHH
287 Confidence 99999999999999999999999876655555668889999999999999999999999999999999889999999999
288
289
290 Q sp|Q9BYF1|ACE2 481 KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL 560 (805)
291 Q Consensus 481 kreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrl 560 (805)
292 .++..|+..|++.++...++++..|...+..++.|....+..+|+-+++|+...++||||.|++.++.++|+++.++|+.
293 T Consensus 481 ~~~y~g~~~~~~~~~~~~~~~~~~H~~~~~~Yy~Y~~s~~~a~ql~~~~~~~~~~~~~l~~~~~~~~~~~g~~~~~~l~~ 560 (615)
294 T 1R42_A 481 KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL 560 (615)
295 T ss_dssp CCCCCCEECSSCCCTTCCGGGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHTTTCCSCGGGCCCTTCHHHHHHHHHHHTT
296 T ss_pred HHHHcCCCCCCCCCcccCChhHcccccCChhHHHHHHHHHHHHHHHHHHHHHhccCCChhhcCcCCChHHHHHHHHHHhc
297 Confidence 99999988777777788899988898766666888899999999999999988889999999999999999999999999
298
299
300 Q sp|Q9BYF1|ACE2 561 GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (805)
301 Q Consensus 561 gksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad 615 (805)
302 |.+.||.-.++.+.|....+..+++.+|+||.+||+.+|++..+||.++|+|++|
303 T Consensus 561 G~s~~~~ell~~~~g~d~~s~~~~~~~~~~l~~~l~~~~~~~~~gw~~~~~~~~~ 615 (615)
304 T 1R42_A 561 GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (615)
305 T ss_dssp TTSSCHHHHHHHHHSSSSCCSHHHHHHHHHHHHHHHHHTSSSCCSCBSSCCTTCC
306 T ss_pred CCCCCHHHHHHHHHCCCCCChHHHHHhHHHHHHHHHHHhcCCCCCCCCCCCCcCC
307 Confidence 9999999999999999889999999999999999999999999999999999985
308
309
310 No 3
311 >6LZG_A Angiotensin-converting enzyme 2 (E.C.3.4.17.23), Spike; Novel Coronavirus, Spike protein, receptor; HET: NAG; 2.5A {Homo sapiens}
312 Probab=100.00 E-value=5.4e-74 Score=545.88 Aligned_cols=597 Identities=100% Similarity=1.567 Sum_probs=545.8 Template_Neff=10.300
313
314 Q sp|Q9BYF1|ACE2 19 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 98 (805)
315 Q Consensus 19 stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlq 98 (805)
316 ||.++.+..+++.++.....+-...+++.|.++++.+++..+..+.+..+.+.+..+.+.....+.+..+.+-..+-+|+
317 T Consensus 1 ~~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~ 80 (597)
318 T 6LZG_A 1 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 80 (597)
319 T ss_dssp CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCGGGCCCHHHHHHHH
320 T ss_pred CChHHHHHHHHHHHHHHHHHHHhHHHhHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHhcCChhhcCCHHHHHHHH
321 Confidence 35567788999999999999999999999999999999988888888899999998888877777766666666777788
322
323
324 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRP 178 (805)
325 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrp 178 (805)
326 .+...+...|+++..++++.+++.+..+|++...|.+++|.+|+.+.+.+..+|+++-|...|.-+|++|++..++.+.+
327 T Consensus 81 ~~~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~ 160 (597)
328 T 6LZG_A 81 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRP 160 (597)
329 T ss_dssp HHHCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEECTTCTTCEEECCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
330 T ss_pred HHHhcCccCCCHHHHHHHHHHHHHHHHHHhcCCccCCCCCCceeccCccHHHHHhcCCCHHHHHHHHHHHHHHhcHHhHH
331 Confidence 77777778889988888889999999999999999998889999999999999999999999999999999988889999
332
333
334 Q sp|Q9BYF1|ACE2 179 LYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISP 258 (805)
335 Q Consensus 179 lyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp 258 (805)
336 ++.+.|.+++++|+.+.|++|.|||...+++++++++||+..++.+-++..++.|+|+|+.+|+|+|.++...|..-+++
337 T Consensus 161 ~l~~lv~~r~~~A~~~Gy~~~~~~~l~~~~~~~~~~~~~~~~~~~~~l~~l~~~v~p~~~~~~~~~~~~~~~~~~~~~~~ 240 (597)
338 T 6LZG_A 161 LYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISP 240 (597)
339 T ss_dssp HHHHHHHHHHHHHHHTTCSSHHHHHHGGGCBCSCTTTCBCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTCCS
340 T ss_pred HHHHHHHHHHHHHHHCCCCCHHHHHHHhhccCCCCCCCCchhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCccCCC
341 Confidence 99999999999999999999999999999999999999999999999999999999999999999999877766543445
342
343
344 Q sp|Q9BYF1|ACE2 259 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 338 (805)
345 Q Consensus 259 igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgn 338 (805)
346 -+..|+|++|.+|+..|+++|....|+.+.+..++++.+..+.+..+++++.++++|-++|+..+...+|+++.+..++.
347 T Consensus 241 ~~~~p~d~~~~~~~~~~~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~~~~r~~k 320 (597)
348 T 6LZG_A 241 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 320 (597)
349 T ss_dssp SSCEETTSSSSSSCSCCGGGHHHHCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCCS
350 T ss_pred CCCCcHHHcccchhhhhhhhHhccCCCCCCCCCCCcHHHHHcCCCHHHHHHHHHHHHHHcCCccCCcchhhhhccCCCCC
351 Confidence 57899999999999999999999999999888889998888899999999999999999999999999999998888888
352
353
354 Q sp|Q9BYF1|ACE2 339 VQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHL 418 (805)
355 Q Consensus 339 vqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhl 418 (805)
356 ...+.|+|.+|+...++.||++|...+.+|+.+.+||+||..|.+.+..||++++.+++.+|+|+++++|+..+.+|.+|
357 T Consensus 321 ~~~~~c~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HElGHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~L 400 (597)
358 T 6LZG_A 321 VQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHL 400 (597)
359 T ss_dssp SSCCCCSCEEEEEETTEEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSTTHHHHHHHHHHHHHHSHHHH
360 T ss_pred CCCCccCccHhcCCCCcEEEEecCCCCHHHHHHHHHHHHHHHHHHHhccCCchhcCCCChHHHHHHHHHHHHHhcCHHHH
361 Confidence 78899999999876689999999999999999999999999999999999999988889999999999999999999999
362
363
364 Q sp|Q9BYF1|ACE2 419 KSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYC 498 (805)
365 Q Consensus 419 ksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc 498 (805)
366 +.++++....+.+.+..++.++.+++..+..+|+..+++.|+|-+|.|+++.+.+.+.||+...+..|++.|++.++...
367 T Consensus 401 ~~~~l~~~~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~~~~~ 480 (597)
368 T 6LZG_A 401 KSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYC 480 (597)
369 T ss_dssp HHTTSSCTTCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTCSCGGGHHHHHHHHCCCCCCEECSSCCCTTCC
370 T ss_pred HHcCCCCcccCCChHHHHHHHHHHHHHHHhhchhHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCCcccC
371 Confidence 99998876554455667888999999999999999999999999999999999999999999999999988776667778
372
373
374 Q sp|Q9BYF1|ACE2 499 DPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKN 578 (805)
375 Q Consensus 499 dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgakn 578 (805)
376 ++++..|+..+..+..|....+..+|+.+.+|+...++||+|.|++.++.++|+++.++|+.|.+.+|.-.++.+.|...
377 T Consensus 481 ~~~~~~H~~~~~~Yy~Y~~~~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~G~s~~~~ell~~~~g~~~ 560 (597)
378 T 6LZG_A 481 DPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKN 560 (597)
379 T ss_dssp GGGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSCSS
380 T ss_pred ChhHccccccChhHHHHHHHHHHHHHHHHHHHHHhccCCChhhCCcCCCHHHHHHHHHHHhcCCCCCHHHHHHHHHCCCC
381 Confidence 88888887655555888899999999999999988889999999999999999999999999999999999999999988
382
383
384 Q sp|Q9BYF1|ACE2 579 MNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (805)
385 Q Consensus 579 mnvrpllnyfeplftwlkdqnknsfvgwstdwspyad 615 (805)
386 .+..++++||+||..||+.+|++..+||.++|.|++|
387 T Consensus 561 ~~~~~l~~~~~~l~~~l~~~~~~~~~gw~~~~~~~~~ 597 (597)
388 T 6LZG_A 561 MNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 597 (597)
389 T ss_dssp CCSHHHHHHHHHHHHHHHHHGGGSCCSCCSSCCTTC-
390 T ss_pred CCcHHHHHhHHHHHHHHHHhhcCCCCCCCCCCCCCCC
391 Confidence 8899999999999999999999999999999999985
392
393
394 No 4
395 >3D0I_B Crystal structure of spike protein; SARS coronavirus, spike protein, receptor-binding; HET: NAG, NDG; 2.9A {Paguma larvata}
396 Probab=100.00 E-value=1.2e-73 Score=545.19 Aligned_cols=596 Identities=98% Similarity=1.548 Sum_probs=544.0 Template_Neff=10.200
397
398 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 99 (805)
399 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqa 99 (805)
400 |-++.++.|+++++.....+-...+.+.|.++++.+++..+....+-.+.+.+.++.......|.+..+.+-..+-+|+.
401 T Consensus 2 ~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~ 81 (597)
402 T 3D0I_B 2 TTEELAKTFLETFNYEAQELSYQSSVASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 81 (597)
403 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCCHHHHHHHHHHHHHHHHHHHHHHHHHHTSCGGGCCCHHHHHHHHH
404 T ss_pred ccHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHhhCChhhcCCHHHHHHHHH
405 Confidence 33567788999999999999999999999999999999888888888899999888887777777666666667778888
406
407
408 Q sp|Q9BYF1|ACE2 100 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPL 179 (805)
409 Q Consensus 100 lqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrpl 179 (805)
410 +...+...|+++...+++.+.+.+..+|++..+|.+++|.+|+.+.+.+..+|.++-|...|..+|++|+...+..+.+.
411 T Consensus 82 l~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~ 161 (597)
412 T 3D0I_B 82 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPL 161 (597)
413 T ss_dssp HSCCTGGGSCHHHHHHHHHHHHHHHHHHHHCEEEETTEEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHTHHHHHHHH
414 T ss_pred HHhcCccCCCHHHHHHHHHHHHHHHHHHhcCCccCCCCCCcccccCccHHHHHhcCCCHHHHHHHHHHHHHHhcHHhHHH
415 Confidence 88888888999888888899999999999999998888888998888999999999999999999999998888899999
416
417
418 Q sp|Q9BYF1|ACE2 180 YEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI 259 (805)
419 Q Consensus 180 yeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispi 259 (805)
420 +.+.+.+++++|+.+.|++|.+||-.++++++.+++||+..++.+-++..++.|+|+|+.+|+|+|.++...|..-+++-
421 T Consensus 162 l~~lv~lr~~~A~~~Gy~~~~~~~l~~~~~~~~~~~~~~~~~~~~~l~~l~~~i~p~~~~~~~~~~~~~~~~~~~~~~~~ 241 (597)
422 T 3D0I_B 162 YEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI 241 (597)
423 T ss_dssp HHHHHHHHHHHHHHTTCSSHHHHHHGGGCBCSSSSSCBCHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHSTTSCCTT
424 T ss_pred HHHHHHHHHHHHHHCCCCCHHHHHHHhcccCCCCCCCCChhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCcccCCCC
425 Confidence 99999999999999999999999999999999999999999999999999999999999999999998776664334455
426
427
428 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
429 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
430 ...|+|++|+||+.-|+.+|....|+.+.+..+++..++.+.+...++++.++++|-++|+..+...||+++....++..
431 T Consensus 242 ~~~p~~~~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~~~~r~~K~ 321 (597)
432 T 3D0I_B 242 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 321 (597)
433 T ss_dssp BCEEGGGSSSSSCSCCGGGGGGTCSCTTSCCSCTHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCCSS
434 T ss_pred CCccHHHccccchhhchhhHhhcCCCCCCCCCCCcHHHHHcCCCHHHHHHHHHHHHHHcCCccCCcchHhhhccCCCCCC
435 Confidence 78999999999999999999999999998888999999888899999999999999999999999899999998888888
436
437
438 Q sp|Q9BYF1|ACE2 340 QKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 419 (805)
439 Q Consensus 340 qkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlk 419 (805)
440 ..+.|+|.+|++..++.||++|...+++|+.|.+||+||+.+.+.+..||++.+..++.+|.|+++++|+..+.+|.+|+
441 T Consensus 322 ~g~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~l~e~~~~~~~~L~ 401 (597)
442 T 3D0I_B 322 QKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 401 (597)
443 T ss_dssp SCCCCSCEEEEEETTEEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSTTHHHHHHHHHHHHHHSHHHHH
444 T ss_pred CCCccCccHhhcCCCcEEEEecCCCCHHHHHHHHHHHHHHHHHHHhccCChhHcCCCChHHHHHHHHHHHHHhcCHHHHH
445 Confidence 88999999999877899999999999999999999999999999998999999888899999999999999999999999
446
447
448 Q sp|Q9BYF1|ACE2 420 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
449 Q Consensus 420 sigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
450 .++++........+..++.++.+++..+..+|+.++++.|+|.+|.|+++.+.+.+.||+..++..|+..|++.++...+
451 T Consensus 402 ~~~~~~~~~~~~~~~~~~~l~~~~l~~l~~l~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~y~g~~~~~~~~~~~~~ 481 (597)
452 T 3D0I_B 402 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 481 (597)
453 T ss_dssp HHTSSCSSCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCSCTTTTTHHHHHHHHHTSCEECSSCCCTTCCC
454 T ss_pred HcCCCCcccCCChHHHHHHHHHHHHHHHhcchHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCCcccCC
455 Confidence 99988765444455677889999999999999999999999999999998899999999999999998887776667778
456
457
458 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 579 (805)
459 Q Consensus 500 paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknm 579 (805)
460 +++..|+..+..++.|....+..+|+.+.+|+...+.||+|.||+..+.++|+++.++|+.|.+.+|.-.++...|....
461 T Consensus 482 ~~~~~H~~~~~~Yy~Y~~s~~~a~~i~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~~G~s~~~~ell~~~~g~d~~ 561 (597)
462 T 3D0I_B 482 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 561 (597)
463 T ss_dssp GGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSCSSC
464 T ss_pred hhHccccccChhHHHHHHHHHHHHHHHHHHHHHhcccCChhhcCcCCCHHHHHHHHHHHhcCCCCCHHHHHHHHHCCCCC
465 Confidence 88888887655558888899999999999999888899999999999999999999999999999999999999999888
466
467
468 Q sp|Q9BYF1|ACE2 580 NVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (805)
469 Q Consensus 580 nvrpllnyfeplftwlkdqnknsfvgwstdwspyad 615 (805)
470 ++.+++.+|+||..||+.+|++..+||.++|.|++|
471 T Consensus 562 ~~~~~~~~~~~l~~~l~~~~~~~~~gw~~~~~~~~~ 597 (597)
472 T 3D0I_B 562 NVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 597 (597)
473 T ss_dssp CSHHHHHHHHHHHHHHHHHGGGSCCSCBTTCCSSCC
474 T ss_pred CcHHHHHhHHHHHHHHHHhhcCCCCCCCCCCCCCCC
475 Confidence 899999999999999999999999999999999985
476
477
478 No 5
479 >5AMB_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1), AMYLOID BETA; HYDROLASE, ANGIOTENSIN-CONVERTING ENZYME, METALLOPROTEASE, AMYLOID-BETA; HET: P6G, PG4, FUC, NAG, PEG, BMA; 1.55A {HOMO SAPIENS}
480 Probab=100.00 E-value=1.2e-69 Score=524.17 Aligned_cols=595 Identities=42% Similarity=0.814 Sum_probs=518.7 Template_Neff=10.000
481
482 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP---LQEIQNLTVKLQ 96 (805)
483 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp---lqeiqnltvklq 96 (805)
484 .-++.+.+||+.++.+...+-...+++.|.++++.+.+..+....+..+.+.+..+.++.+.... ++.+..-..+-+
485 T Consensus 12 ~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~ 91 (629)
486 T 5AMB_A 12 ADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRI 91 (629)
487 T ss_dssp SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGCSCHHHHHH
488 T ss_pred CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhhccHHHhcCCHHHHHH
489 Confidence 34577889999999999999999999999999999999888888888888888887766433211 122233345556
490
491
492 Q sp|Q9BYF1|ACE2 97 LQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQL 176 (805)
493 Q Consensus 97 lqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkql 176 (805)
494 |+.+...+...|+++..+++..+.+.|+.+|++...|.++.+..|+.+.+.+..+|+++-|...|.-+|+.|+...+..+
495 T Consensus 92 l~~l~~~~~~~L~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~ 171 (629)
496 T 5AMB_A 92 IGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLPQKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPL 171 (629)
497 T ss_dssp HHHHTCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEEC---CCCEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
498 T ss_pred HHHHHHhcccCCCHHHHHHHHHHHHHHHHHHhhccccCCCCCCceeecChhHHHHHHhCCCHHHHHHHHHHHHHHhCccc
499 Confidence 66666666677888887888889999999999999998777778888888999999999999999999999999888999
500
501
502 Q sp|Q9BYF1|ACE2 177 RPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-Y 255 (805)
503 Q Consensus 177 rplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-y 255 (805)
504 ++++.+.|-+++++|+...|++|.+||..+|+. +...+.++..++.|+|+|+.+|+|+|.++...|.. .
505 T Consensus 172 ~~~l~~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~~~~~l~~l~~~i~~~~~~~~~~~~~~~~~~~g~~~ 241 (629)
506 T 5AMB_A 172 KPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNS----------PTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRY 241 (629)
507 T ss_dssp HHHHHHHHHHHHHHHHTTTCSSHHHHHHHTTCC----------TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTT
508 T ss_pred HHHHHHHHHHHHHHHHHcCCCCHHHHHHHhhCC----------ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccc
509 Confidence 999999999999999999999999999887642 34556677888999999999999999987665542 2
510
511
512 Q sp|Q9BYF1|ACE2 256 ISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTD 335 (805)
513 Q Consensus 256 ispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltd 335 (805)
514 +++-+.+|+|++|++|+..|+++|.+++|+.+....+|++.++.+.+....+++.++++|.++|++.++..||++++...
515 T Consensus 242 ~~~~~~ip~dll~~~~~~~~~~~~~~~~p~~~~~~~~v~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~~~~~~~~~ 321 (629)
516 T 5AMB_A 242 INLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEK 321 (629)
517 T ss_dssp CCTTSCEETTSSSSTTSCCCGGGHHHHCSCTTSCCCCTHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSC
518 T ss_pred cCCCCCCCHHHccChhhhhhhhhhcccccCCCCCCCCCcHHHHhcCCCHHHHHHHHHHHHHhCCCCCCChhHhhcccccC
519 Confidence 33445679999999999999999999999988888889999999888899999999999999999999999999999888
520
521
522 Q sp|Q9BYF1|ACE2 336 PGNVQKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAAT 414 (805)
523 Q Consensus 336 pgnvqkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaat 414 (805)
524 |+.....+|||.+|++.. ++.||++|...+++|+.|.+|||||..|.+.+..||++.+.+++.+|||+++++|+..+.+
525 T Consensus 322 ~~k~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~ 401 (629)
526 T 5AMB_A 322 PADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVST 401 (629)
527 T ss_dssp CTTCCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCSSHHHHHHHHHHHHHHHTS
528 T ss_pred CCCCCccccccchhhccCCCCeEEEecCCCCHHHHHHHHHHHHHHHHHHHcCCCCHHHcCCCCHHHHHHHHHHHHHHhcC
529 Confidence 887777899999999985 7899999999999999999999999999999999999999999999999999999999999
530
531
532 Q sp|Q9BYF1|ACE2 415 PKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHD 494 (805)
533 Q Consensus 415 pkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphd 494 (805)
534 |.+|+.++++... +...+..++.++++++..+..+|+.++++.|+|.+|.|+++.+++.+.||+..++..|+..|.+.+
535 T Consensus 402 ~~~L~~~~~~~~~-~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~ 480 (629)
536 T 5AMB_A 402 PEHLHKIGLLDRV-TNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRN 480 (629)
537 T ss_dssp HHHHHHTTSCCCC-CCSHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTSSCGGGHHHHHHHHCCCCCCEECSSCCC
538 T ss_pred HHHHHHcCCCCCC-CCCcHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHhhCCCCChhhHHHHHHHHHHHhCCCCCCCCCC
539 Confidence 9999999987543 223345678899999999999999999999999999999999999999999999999987766667
540
541
542 Q sp|Q9BYF1|ACE2 495 ETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVV 574 (805)
543 Q Consensus 495 etycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvv 574 (805)
544 +...||++..|+..+..++.|....+.++|+-+.+|+...++||||+||+..+.++|+++.++|+.|.+.+|.-.++.+.
545 T Consensus 481 ~~~~~~~~~~H~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~pl~~~~~~~~~~~g~~~~~~L~~G~s~~~~ell~~~~ 560 (629)
546 T 5AMB_A 481 ETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMV 560 (629)
547 T ss_dssp TTCCGGGGSTTTTTTCCCHHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHHHTTSSCHHHHHHHHH
548 T ss_pred cccCCcCcccccCCChhHHHHHHHHHHHHHHHHHHHHHcCCCCCcccCCccCCHHHHHHHHHHHhcCCCCcHHHHHHHHh
549 Confidence 78889999999876556889999999999999999998889999999999999999999999999999999999999999
550
551
552 Q sp|Q9BYF1|ACE2 575 GAKNMNVRPLLNYFEPLFTWLKDQNK--NSFVGWST-DWSPYADQSIKVRISLK 625 (805)
553 Q Consensus 575 gaknmnvrpllnyfeplftwlkdqnk--nsfvgwst-dwspyadqsikvrislk 625 (805)
554 |....+..+++.+|+||..||+.+|+ +.-+||.. +|.|++..+++++|++-
555 T Consensus 561 G~d~~~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~~~~~~~~~~~~~~~~ 614 (629)
556 T 5AMB_A 561 GLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLV 614 (629)
557 T ss_dssp SCSSCCSHHHHHHHHHHHHHHHHHHHHHTCCSSCSCTTCCCCCCTTCSCC----
558 T ss_pred CCCCCChHHHHHHHHHHHHHHHHHHHhcCcccCCcccCCCCCCCCCCCCCCCCC
559 Confidence 99889999999999999999999999 56699996 99999999999999983
560
561
562 No 6
563 >6H5W_A Angiotensin-converting enzyme (E.C.3.2.1.-,3.4.15.1); Angiotensin-1 converting enzyme, ACE inhibitor; HET: BO3, CSO, FUC, FT8, P6G, EDO, BMA, IMD, NAG; 1.37A {Homo sapiens}
564 Probab=100.00 E-value=4.4e-61 Score=455.72 Aligned_cols=579 Identities=43% Similarity=0.858 Sum_probs=503.4 Template_Neff=10.400
565
566 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
567 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
568 +..+..||+.++.....+-...+++.|.++++++++.++....+-.+.+.+..+..+.+..|..+.+.+-.++-.++.+.
569 T Consensus 5 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 84 (591)
570 T 6H5W_A 5 EAEASKFVEEYDRTSQVVWNEYAGANWNYNTNITTETSKILLQKNMQIAQHTLKYGTQARKFDVNQLQNTTIKRIIKKVQ 84 (591)
571 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCGGGCCCHHHHHHHHHHT
572 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhhHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcCcccCCCHHHHHHHHHHH
573 Confidence 55678899999999999999999999999999999999999989999999999888877766645555555666666666
574
575
576 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYE 181 (805)
577 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrplye 181 (805)
578 ..+...|+++....+..+...+..+|++.++|.++ .+|+.+.+.+..+|+++-|...|.-+|+.|+...+..++|.+.
579 T Consensus 85 ~~~~~~L~~~~~~~~~~l~~~~~~~~~~~~~~~~~--g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l~ 162 (591)
580 T 6H5W_A 85 DLERAALPAQELEEYNKILLDMETTYSVATVCHPQ--GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYP 162 (591)
581 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEECTT--SCEEECCCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHHTTTHH
582 T ss_pred hhhhccCCHHHHHHHHHHHHHHHhhhccceecCCC--CceecCChhHHHHHhhCCCHHHHHHHHHHHHHHhhHHhHHHHH
583 Confidence 66666778876667777788888999999999874 4677788899999999999999999999999887889999999
584
585
586 Q sp|Q9BYF1|ACE2 182 EYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPIG 260 (805)
587 Q Consensus 182 eyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispig 260 (805)
588 +.+-+++++|+...|++|.+||..+|+. +.+.+.++..++.++|+|+.+|+|+|.|+...+.. -+++-+
589 T Consensus 163 ~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~v~~~l~~l~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~ 232 (591)
590 T 6H5W_A 163 KYVELINQAARLNGYVDAGDSWRSMYET----------PSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEG 232 (591)
591 T ss_dssp HHHHHHHHHHHHTTCSSHHHHHHHTTCC----------TTHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHCGGGCCTTS
592 T ss_pred HHHHHHHHHHHHCCCCCHHHHHHhccCC----------ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccCCCCC
593 Confidence 9999999999999999999999887732 34557788889999999999999999987544432 244557
594
595
596 Q sp|Q9BYF1|ACE2 261 CLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQ 340 (805)
597 Q Consensus 261 clpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvq 340 (805)
598 -+|+|++|.+|+.-|+++|.++.|+...+..++++++..+.+...++++.++++|.+.|+..|..+||+++....|+...
599 T Consensus 233 ~~p~~~~~~~~~~~~~~~~~~~~p~~~~~~~~v~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~~~~~~~~~~~k~~ 312 (591)
600 T 6H5W_A 233 PIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWQKSMLEKPTDGR 312 (591)
601 T ss_dssp CEETTSSSSTTSSCCGGGHHHHCSCTTSCCCCHHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSSSC
602 T ss_pred CCcHHHchhhhhHhhHhhhhccCCCCCCCCCCcHHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChHHHhhccccCCCCCC
603 Confidence 88999999999999999999999998888888888877777888999999999999999988889999998877777655
604
605
606 Q sp|Q9BYF1|ACE2 341 KAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 419 (805)
607 Q Consensus 341 kavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlk 419 (805)
608 ..+|||.++++.. ++.||++|...+.+++.|.+||+||..|.+.+..||++++.++.-+|+|+++++|+..+.+|.+|+
609 T Consensus 313 ~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~l~ 392 (591)
610 T 6H5W_A 313 EVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLH 392 (591)
611 T ss_dssp CCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHHHH
612 T ss_pred cceecceeeeCcCCCceEEEecCCCCHHHHHHHHHHHHHHHHHHHhcCCCHHHccCCChHHHHHHHHHHHHHhcCHHHHH
613 Confidence 6799999999875 689999999999999999999999999999999999999888999999999999999999999999
614
615
616 Q sp|Q9BYF1|ACE2 420 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
617 Q Consensus 420 sigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
618 .++++... ..+.+..++.++.+++..+..+|+.++++.|+|-++.|.++.+++-+.||+...+..|+..|.+......|
619 T Consensus 393 ~~~~~~~~-~~~~~~~~~~l~~~~~~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~~~~~~ 471 (591)
620 T 6H5W_A 393 SLNLLSSE-GGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFD 471 (591)
621 T ss_dssp HTTSSCCC-CSCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTSSCTTTHHHHHHHHCCCCCCEECSSCCCTTCCG
622 T ss_pred hcCCCCCC-CCChHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHhCCCCCHHhHHHHHHHHHHHHcCCCCCCCCCcccCC
623 Confidence 99987653 23334467788899999999999999999999999999888889999999999999898766555566778
624
625
626 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 579 (805)
627 Q Consensus 500 paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknm 579 (805)
628 |++..|......+..|....+..+|+.+.+|+...|+||+|.|++..+.++|+++-++|+.|.+.+|.-.++...|..-.
629 T Consensus 472 ~~~~~H~~~~~y~y~Y~~~~~~a~ql~~~~~~~~~~~~~l~~~~~~~~~~~g~~~~~~l~~G~s~~~~ell~~~~g~d~~ 551 (591)
630 T 6H5W_A 472 PGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPQM 551 (591)
631 T ss_dssp GGGSTTTTTTCCSHHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSSCSC
632 T ss_pred CcccccCCCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCcccCCccCCHHHHHHHHHHHHcCCCCCHHHHHHHHHCCCCC
633 Confidence 88888888666778888888999999999999888899999999998899999999999999999999999999998878
634
635
636 Q sp|Q9BYF1|ACE2 580 NVRPLLNYFEPLFTWLKDQNKN--SFVGWST-DWSPY 613 (805)
637 Q Consensus 580 nvrpllnyfeplftwlkdqnkn--sfvgwst-dwspy 613 (805)
638 +..+++.+|+|+..||+.+|+. --+||.. .|.|-
639 T Consensus 552 ~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~~~~ 588 (591)
640 T 6H5W_A 552 SASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPN 588 (591)
641 T ss_dssp CSHHHHHHHHHHHHHHHHHHHHHTCCCSCSSTTCCCC
642 T ss_pred ChHHHHHhHHHHHHHHHHHHHhhCCccCCCccCCCCC
643 Confidence 8999999999999999999875 4599987 67664
644
645
646 No 7
647 >6S1Y_A Angiotensin-converting enzyme (E.C.3.4.-.-); metalloprotease, mosquito control, insecticide design; HET: PEG, EDO, NAG, BMA, KSN; 2.2A {Anopheles gambiae}
648 Probab=100.00 E-value=4.6e-59 Score=450.26 Aligned_cols=579 Identities=37% Similarity=0.727 Sum_probs=484.7 Template_Neff=10.000
649
650 Q sp|Q9BYF1|ACE2 21 IEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQAL 100 (805)
651 Q Consensus 21 ieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqal 100 (805)
652 -++++.++++.++.....+-...+++.|.++++.+.+..+....+-.+.+.+..+..+...-+....+..-..+-+++.+
653 T Consensus 11 ~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~l~~~ 90 (621)
654 T 6S1Y_A 11 SETEISQIVEWIEQRYQQTKAHQTLAAWEYGSNLTEFNLSKKTKAAADFAEVAKAVAEELQQFKTDQLTNATLKRRIKKL 90 (621)
655 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCSSSCCCHHHHHHHHHH
656 T ss_pred CHHHHHHHHHHHHHHHHHHHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCHHHHHHHHHH
657 Confidence 34677889999999999999999999999999999988887666777777777654432111111122233455566666
658
659
660 Q sp|Q9BYF1|ACE2 101 QQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNP-QECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPL 179 (805)
661 Q Consensus 101 qqngssvlsedkskrlntilntmstiystgkvcnpdnp-qeclllepglneimansldynerlwaweswrsevgkqlrpl 179 (805)
662 ...+...|+++..+++..++..++.+|++..+|.++.+ .+++.+.+.+..+|+++-|...|--+|++|++..+..+.++
663 T Consensus 91 ~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~ 170 (621)
664 T 6S1Y_A 91 AKLGYAALPADQFKELLGAIASMESNYAKAKFCAYGDATKCDLSLDPELTEIFANHREPEELKYYWVQWYNATGAPVRES 170 (621)
665 T ss_dssp TCCGGGGSCHHHHHHHHHHHHHHHHHHHHCCBCBTTBTTCCCBCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHH
666 T ss_pred HHhccccCCHHHHHHHHHHHHHHHHHHHhhccccCCCCCCCcccCChHHHHHHHhCCCHHHHHHHHHHHHHhcChhHHHH
667 Confidence 66666678888777788888899999999888765422 23455668899999999999999999999999888899999
668
669
670 Q sp|Q9BYF1|ACE2 180 YEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISP 258 (805)
671 Q Consensus 180 yeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yisp 258 (805)
672 +.+.|-+++++|+...|.+|.+|+..++++ +.+.+-++..++.++|+++.+++|++.++...|.. -+++
673 T Consensus 171 l~~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~v~~~l~~l~~~v~~~~~~~~~~~~~~~~~~~g~~~~~~ 240 (621)
674 T 6S1Y_A 171 FQKYVELNRQAALRNNFSSGAAVWLNEYDD----------STFEQQVDDVIEQIRPLYEQLHAYVRYKLRQKYGDKLVSP 240 (621)
675 T ss_dssp HHHHHHHHHHHHHHTTCSSHHHHHHHTTCC----------TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCS
676 T ss_pred HHHHHHHHHHHHHHCCCCCHHHHHHhcCCc----------hhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccCCCCC
677 Confidence 999999999999999999999999876642 34556677788899999999999999987554432 3456
678
679
680 Q sp|Q9BYF1|ACE2 259 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 338 (805)
681 Q Consensus 259 igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgn 338 (805)
682 -+-+|+|+||.+|+.-|..+|.+..|+.+....++++.++.+-+..+++++.++++|-++|+..++..||++++...|..
683 T Consensus 241 ~~~ip~~~l~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~v~~~~~~ 320 (621)
684 T 6S1Y_A 241 TGPIPMHLLGNLWAQTWDNIADFTTPFPEKKLLDVTDEMIRQGYTPIKMFQMGDDFFTSLNMTKLPQTFWDKSILEKPTD 320 (621)
685 T ss_dssp SSCEEGGGSSSTTCSCCGGGTTTTCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSS
686 T ss_pred CCCCcHHHhhcchhccchhhhhhcCCCCCcccCCCcHHHHHCCCCHHHHHHHHHHHHHHCCCCCCChhHhhhhhccCCCC
687 Confidence 78999999999999999999999999876666778888988888899999999999999999999999999999875432
688
689
690 Q sp|Q9BYF1|ACE2 339 VQKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKH 417 (805)
691 Q Consensus 339 vqkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkh 417 (805)
692 -....|||..+.+.. +|.||++|+..+.+|+.|.+||+||..|.+.+..||++.+.+++.+|+|+++++|+..+.+|.+
693 T Consensus 321 ~k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~~~~~~~~~p~~~~~~~~~~~~E~~s~~~e~~~~~~~~ 400 (621)
694 T 6S1Y_A 321 GRDLVCHASAWDFFAIDDVRIKQCTRVNMREFFVVHHELGHIQYYLQYQHQPVEFRGGANPGFHEAVGDVLSLSVSTPKH 400 (621)
695 T ss_dssp CCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHH
696 T ss_pred CCCCCCchhhhhccCCCCEEEEeCCCCCHHHHHHHHHHHHHHHHHHHhccCCchhcCCCChHHHHHHHHHHHHHhcCHHH
697 Confidence 222468888888875 6999999999999999999999999999999999999999999999999999999999999999
698
699
700 Q sp|Q9BYF1|ACE2 418 LKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
701 Q Consensus 418 lksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
702 |+.++++.. .....+..++.++++++..+..+|+..++.+|++.++.|.+..+.+-+.||+...+..|+..|.+.++..
703 T Consensus 401 L~~~~l~~~-~~~~~~~~~~~l~~~~l~~l~~~~~~~~~d~fe~~l~~~~~~~~~l~~~~~~l~~~y~g~~~~~~~~~~~ 479 (621)
704 T 6S1Y_A 401 LKKVGLLKD-YEEDEQVKINQFYRAGVTKLVFLPFAYTLDKYRWGVFRGDIKPREYNCKFWEMRSRYSGVEPPVVRTEQD 479 (621)
705 T ss_dssp HHHTTSSCC-CCCCHHHHHHHHHHHCCCCCTHHHHHHHHHHHHHHHHHTSSCGGGHHHHHHHHHHHHHCEECSSCEETTC
706 T ss_pred HHHcCCCCC-CCCCHHHHHHHHHHHHHHHhhhhHHHHHHHHHHHHHHcCCCChHHHHHHHHHHHHHHcCCCCCCCCChhh
707 Confidence 999998753 3333345667888899999999999889999999999998877888999999999999976665566677
708
709
710 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALE 571 (805)
711 Q Consensus 498 cdpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlale 571 (805)
712 .||+...|+.....++.|....+..+|+-+.+|+...+ ++|||.||+..+.++|.++.++|+.|.+.+|.-.++
713 T Consensus 480 ~~~~~~~H~~~~~~~~~Y~~~~~~a~qi~~~~~~~~~~~~~~~~~~~l~~c~~~~~~~~~~~~~~~l~~G~s~~~~ell~ 559 (621)
714 T 6S1Y_A 480 FDPPAKYHVSADVEYLRYFVSYVIQFQFHRAACALAGEYVKGDPEKTLNNCDIYQSTAAGNQLKEMLALGSSKPWPDAME 559 (621)
715 T ss_dssp CCGGGSHHHHTTCCSHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCTTSCCCTTCHHHHHHHHHHHHTTTSSCHHHHHH
716 T ss_pred CCcchheeecCCchHHHHHHHHHHHHHHHHHHHHHhCCccCCCCCCCcccCCccCCHHHHHHHHHHHhcCCCCCHHHHHH
717 Confidence 88888888875556888999999999999999987643 579999999999999999999999999999999999
718
719
720 Q sp|Q9BYF1|ACE2 572 NVVGAKNMNVRPLLNYFEPLFTWLKDQNKN--SFVGWSTDW 610 (805)
721 Q Consensus 572 nvvgaknmnvrpllnyfeplftwlkdqnkn--sfvgwstdw 610 (805)
722 ...|....+..+++.||+|+.+||+.+|++ --+||..+|
723 T Consensus 560 ~~~G~d~~s~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~ 600 (621)
724 T 6S1Y_A 560 VLTGERKMSADAILEYFDPLYQWLLEENKRLGAHVGWTDSQ 600 (621)
725 T ss_dssp HHHSCCSCCTHHHHHHTHHHHHHHHHHHHHHTCCCSCCCCC
726 T ss_pred HHHCCCCCChHHHHHHHHHHHHHHHHHHHHhCCCCCCCccc
727 Confidence 999988889999999999999999988875 459999775
728
729
730 No 8
731 >4CA5_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.2.1.-, 3.4.15.1); HYDROLASE, ZINC METALLOPEPTIDASE, INHIBITOR BINDING; HET: FUC, 3EF, ACT, NAG; 1.85A {HOMO SAPIENS}
732 Probab=100.00 E-value=3.9e-58 Score=435.55 Aligned_cols=578 Identities=43% Similarity=0.863 Sum_probs=497.1 Template_Neff=10.400
733
734 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
735 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
736 +..++.|++.++.+...+-...+++.|.++++.+++..+....+-.+.+.++.+..++...|..+.+.+-..+-+++.+.
737 T Consensus 5 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 84 (589)
738 T 4CA5_A 5 EAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQ 84 (589)
739 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHHTSCGGGCCCHHHHHHHHHHT
740 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcChhhCCCHHHHHHHHHHH
741 Confidence 56778999999999999999999999999999999999988888888888888777766655333444445566666666
742
743
744 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYE 181 (805)
745 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrplye 181 (805)
746 ..+...|+++.-+++..+...+..+|++..+|.++ .+|+.+.+.+..+|.++-|...|--+|++|+...+..+.+.+.
747 T Consensus 85 ~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~--g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l~ 162 (589)
748 T 4CA5_A 85 DLERAALPAQELEEYNKILLDMETTYSVATVCHPN--GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYP 162 (589)
749 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCCEECTT--SCEECCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHHTTTHH
750 T ss_pred hhhhccCCHHHHHHHHHHHHHHHhhhccceecCCC--CCeecCChhHHHHHhhCCCHHHHHHHHHHHHHHhhHHHHHHHH
751 Confidence 66667888887777788888899999998888775 3567777889999999999999999999999988889999999
752
753
754 Q sp|Q9BYF1|ACE2 182 EYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPIG 260 (805)
755 Q Consensus 182 eyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispig 260 (805)
756 +.+-+++++|+...|.+|.+||..+|+. +.+.+.++..++.++|+|+.+|+|++.++...|.. -++.-+
757 T Consensus 163 ~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~v~~~l~~l~~~v~p~~~~l~~~~~~~~~~~~g~~~~~~~~ 232 (589)
758 T 4CA5_A 163 KYVELINQAARLNGYVDAGDSWRSMYET----------PSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEG 232 (589)
759 T ss_dssp HHHHHHHHHHHHTTCSSHHHHHHGGGCC----------TTHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHCTTTCCTTS
760 T ss_pred HHHHHHHHHHHHcCCCCHHHHHHHccCC----------ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccCCCCC
761 Confidence 9999999999999999999999887732 33457788889999999999999999987554431 133446
762
763
764 Q sp|Q9BYF1|ACE2 261 CLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQ 340 (805)
765 Q Consensus 261 clpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvq 340 (805)
766 -.|+|++|.+|+.-|+++|....||......++++.+..+.+...++++.++.+|-++|+..+...+|+++....++.-.
767 T Consensus 233 ~~p~~~~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~~~~d~~~r~~K~~ 312 (589)
768 T 4CA5_A 233 PIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGR 312 (589)
769 T ss_dssp CEETTSSSSTTSSCCGGGHHHHCSCTTSCCCCHHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSSSC
770 T ss_pred CCcHHHhhhhhhhccccchhhcCCCCCCCCCCcHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHhchhhccCCCCCC
771 Confidence 78999999999999999999999998888888888888888888999999999999999877888899998887777665
772
773
774 Q sp|Q9BYF1|ACE2 341 KAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 419 (805)
775 Q Consensus 341 kavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlk 419 (805)
776 ...|||..+++.. ++.||++|...+.+++.|.+||+||..+.+.+..+|++.+.+++-+|+|+++++|+..+.+|.+|+
777 T Consensus 313 ~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~l~ 392 (589)
778 T 4CA5_A 313 EVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLH 392 (589)
779 T ss_dssp CCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHSTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHHHH
780 T ss_pred CceecceeEeCcCCCcEEEEEcCCCCHHHHHHHHHHHHHHHHHHHcCCCCHHHccCCChHHHHHHHHHHHHHhcCHHHHH
781 Confidence 6789999998864 689999999999999999999999999999988999999888999999999999999999999999
782
783
784 Q sp|Q9BYF1|ACE2 420 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
785 Q Consensus 420 sigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
786 .++++... +.+.+..++.++.+++..+..+|+.++++.|.+.++.|.+..+.+-+-||+...+.-|+..|.+......|
787 T Consensus 393 ~~~~~~~~-~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~~~~~~ 471 (589)
788 T 4CA5_A 393 SLNLLSSE-GGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFD 471 (589)
789 T ss_dssp HTTSSCCC-CSCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTSSCTTTHHHHHHHHCCCCCCEECSSCCCTTCCG
790 T ss_pred HcCCCCCC-CCChHHHHHHHHHHHHHHHhhchHHHHHHHHHHHHhCCCCChHhHHHHHHHHHHHHcCCCCCCCCChhhCC
791 Confidence 99987653 22334456788999999999999999999999999999888888999999988888887655444455677
792
793
794 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 579 (805)
795 Q Consensus 500 paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknm 579 (805)
796 |++..|......+..|....+..+|+-+.+|+...+.||+|.|++..+.++|.++.++|+.|.+.||.-.++.+.|....
797 T Consensus 472 ~~~~~H~~~~~y~y~Y~~~~~~a~~l~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~~G~~~~~~ell~~~~g~d~~ 551 (589)
798 T 4CA5_A 472 PGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNM 551 (589)
799 T ss_dssp GGGSTTTTTTCCCHHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHHTTTSSCHHHHHHHHHSSCSC
800 T ss_pred ccccccCCCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHHHHHCCCCC
801 Confidence 77888887666778888888999999999999888889999999998899999999999999999999999999998888
802
803
804 Q sp|Q9BYF1|ACE2 580 NVRPLLNYFEPLFTWLKDQNKNS--FVGWST-DWSP 612 (805)
805 Q Consensus 580 nvrpllnyfeplftwlkdqnkns--fvgwst-dwsp 612 (805)
806 ++.+++.+|+||..||+.+|+.. -+||.. .|.|
807 T Consensus 552 ~~~~~~~~~~~l~~~l~~~~~~~~~~~g~~~~~~~~ 587 (589)
808 T 4CA5_A 552 SASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTP 587 (589)
809 T ss_dssp CSHHHHHHHHHHHHHHHHHHHHTTCCCSCSSTTCCC
810 T ss_pred ChHHHHHhHHHHHHHHHHHHHhhCCccCCcccCCCC
811 Confidence 99999999999999999998754 489988 7876
812
813
814 No 9
815 >5A2R_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1); HYDROLASE, ANGIOTENSIN CONVERTING ENZYME, DROSOPHILA; HET: NAG; 1.85A {DROSOPHILA MELANOGASTER}
816 Probab=100.00 E-value=2.8e-56 Score=425.09 Aligned_cols=579 Identities=37% Similarity=0.721 Sum_probs=483.2 Template_Neff=10.300
817
818 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
819 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
820 ++...++|++++.....+-.....+.|.++++.+++..+..+.+..+.+.+.++.......|.++....-..+-+|+.+.
821 T Consensus 5 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 84 (598)
822 T 5A2R_A 5 EIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALT 84 (598)
823 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHGGGSCGGGCSCHHHHHHHHHHH
824 T ss_pred HHHHHHHHHHHHHHHHHHhcHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHhcchhcchhhCCCHHHHHHHHHHH
825 Confidence 35677899999999999999999999999999999988877777888888887766655444422222233455566666
826
827
828 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDN-PQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY 180 (805)
829 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdn-pqeclllepglneimansldynerlwaweswrsevgkqlrply 180 (805)
830 ..+...|+++.-++++..+..++.+|++...|..+. ...++.+.+.+..+|+++-|...|--+|+.|+...+..+.+.+
831 T Consensus 85 ~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l 164 (598)
832 T 5A2R_A 85 KLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQF 164 (598)
833 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCCBCCSSCTTCCCBCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHHH
834 T ss_pred HhcccCCCHHHHHHHHHHHHHHHHHHhccccCCCCCCCCCcccCCHHHHHHHHcCCCHHHHHHHHHHHHHHccHHHHHHH
835 Confidence 677778888888888888889999999887776432 1245566788999999999999999999999998888999999
836
837
838 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPI 259 (805)
839 Q Consensus 181 eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispi 259 (805)
840 .+.+-+++++|+...|++|.+|+..+++ ...+.+-++..++.|+|+|+.+|+|++.++...|.. -++.-
841 T Consensus 165 ~~l~~~r~~~A~~~Gy~s~~~~~l~~~~----------~~~v~~~l~~l~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~ 234 (598)
842 T 5A2R_A 165 ERYVELNTKAAKLNNFTSGAEAWLDEYE----------DDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSET 234 (598)
843 T ss_dssp HHHHHHHHHHHHHTTCSSHHHHHHGGGC----------CTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCSS
844 T ss_pred HHHHHHHHHHHHHCCCCCHHHHHHhccC----------CchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCccccCCC
845 Confidence 9999999999999999999999976543 223345566677889999999999999987554321 12334
846
847
848 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
849 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
850 +-+|+|++|++|++-|..+|.+..|+.+++..++++.+....+....+++-++++|-++|+..+..++|++++...|..-
851 T Consensus 235 ~~~p~~l~g~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~w~~~~~~~~~~~ 314 (598)
852 T 5A2R_A 235 GPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDG 314 (598)
853 T ss_dssp SCEEGGGSSSTTCSCCGGGHHHHCSCTTSCCCCTHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSSC
854 T ss_pred CCCCHHHhhchhhhhhHhhhhhcCCCCCCCCCCchHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChhhhhhhhccCCCCC
855 Confidence 56799999999999999999999999888777888888777788899999999999999999988999999987644321
856
857
858 Q sp|Q9BYF1|ACE2 340 QKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHL 418 (805)
859 Q Consensus 340 qkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhl 418 (805)
860 ....|||.++.+.. ++.||++|...+.+|+.|.+||+||..+.+.+..||++.+++.+.+|+|+++++|++.+.+|.+|
861 T Consensus 315 k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~L 394 (598)
862 T 5A2R_A 315 RDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHL 394 (598)
863 T ss_dssp CCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHHH
864 T ss_pred CCCccccceEeCcCCCCeEEEecCCCCHHHHHHHHHHHHHHHHHHHccCCChhHccCCChHHHHHHHHHHHHHhcCHHHH
865 Confidence 11358888888774 68999999999999999999999999999999889999999999999999999999999999999
866
867
868 Q sp|Q9BYF1|ACE2 419 KSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYC 498 (805)
869 Q Consensus 419 ksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc 498 (805)
870 +.++++. ....+.+..++.++.+++..+..+|+......|++-++.|++....+-+.||+...+.-|++.|.+.+...+
871 T Consensus 395 ~~~~~~~-~~~~~~~~~~~~l~~~~l~~l~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~ 473 (598)
872 T 5A2R_A 395 EKIGLLK-DYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDF 473 (598)
873 T ss_dssp HHTTSSC-SCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTCSCGGGHHHHHHHHHHHHHCEECSSCEETTCC
874 T ss_pred HHcCCCC-ccCCChHHHHHHHHHHHHHHhhhcHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCChhhC
875 Confidence 9999874 333444567788899999999999998888999999999988778899999999999989876655555557
876
877
878 Q sp|Q9BYF1|ACE2 499 DPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALEN 572 (805)
879 Q Consensus 499 dpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlalen 572 (805)
880 ++++..|+..+..++.|....+..+|+-+.+|+...+ .||+|.||...+.++|+++.++|+.|.+.||.-.++.
881 T Consensus 474 ~~~~~~hi~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~G~s~~~~e~~~~ 553 (598)
882 T 5A2R_A 474 DAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEA 553 (598)
883 T ss_dssp CGGGSHHHHTTCCCHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHH
884 T ss_pred CCccceeecCCchHHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHHH
885 Confidence 7888888775556788888889999999998886544 6799999999889999999999999999999999999
886
887
888 Q sp|Q9BYF1|ACE2 573 VVGAKNMNVRPLLNYFEPLFTWLKDQNKNSF--VGWSTDWS 611 (805)
889 Q Consensus 573 vvgaknmnvrpllnyfeplftwlkdqnknsf--vgwstdws 611 (805)
890 ..|..-.+..+++.+|.|+-.||+.+|+..- +||..+|.
891 T Consensus 554 ~~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~w~~~~~ 594 (598)
892 T 5A2R_A 554 FNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNK 594 (598)
893 T ss_dssp HHSCCSCCSHHHHHHHHHHHHHHHHHHHHTTCCCSCCCCSC
894 T ss_pred HhCCCCCChHHHHHHHHHHHHHHHHhHHhcCCcCCccCCCc
895 Confidence 9999878999999999999999999987665 99999873
896
897
898 No 10
899 >4ASR_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1), BRADYKININ; HYDROLASE, ZINC METALLOPROTEASE, SUBSTRATE RECOGNITION; HET: MAN, NAG, FLC, BMA; 1.9A {DROSOPHILA MELANOGASTER}
900 Probab=100.00 E-value=2.9e-56 Score=426.35 Aligned_cols=578 Identities=37% Similarity=0.724 Sum_probs=486.1 Template_Neff=10.200
901
902 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
903 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
904 +.+...||..++.....+-....++.|.++++.+++..+..+.+..+.+.+..+..+.+..|.++...+-..+-+|+.+.
905 T Consensus 6 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 85 (598)
906 T 4ASR_A 6 EIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALT 85 (598)
907 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHGGGSCGGGCSCHHHHHHHHHHH
908 T ss_pred HHHHHHHHHHHHHHHHHHhCHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHhcchhcchhcCCCHHHHHHHHHHH
909 Confidence 46678899999999999999999999999999999988888788888888888777666555533333334555666666
910
911
912 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDN-PQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY 180 (805)
913 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdn-pqeclllepglneimansldynerlwaweswrsevgkqlrply 180 (805)
914 ..+...|+++.-++++..+..+..+|++...|.... ..+++.+.|.+..+|.++-|...|--+|++|++..+..+.+++
915 T Consensus 86 ~~~~~~L~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l 165 (598)
916 T 4ASR_A 86 KLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQF 165 (598)
917 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCCBCCSSCTTCCCBCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHHH
918 T ss_pred HhccccCCHHHHHHHHHHHHHHHHHhhccccCCCCCCCCccccCCHHHHHHHHcCCCHHHHHHHHHHHHHHhcHHHHHHH
919 Confidence 666678888888888888899999999887776432 1255566788999999999999999999999998888999999
920
921
922 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPI 259 (805)
923 Q Consensus 181 eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispi 259 (805)
924 .+.+-+++++|+...|.+|.+|+..++ +...+.+-++..++.++|+++.+|+|+|.++...|.. .+++-
925 T Consensus 166 ~~lv~~r~~~A~~~Gy~s~~~~~l~~~----------~~~~v~~~l~~l~~~i~~~~~~l~~~~~~~~~~~~~~~~~~~~ 235 (598)
926 T 4ASR_A 166 ERYVELNTKAAKLNNFTSGAEAWLDEY----------EDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSET 235 (598)
927 T ss_dssp HHHHHHHHHHHHHTTCSSHHHHHHGGG----------CCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCSS
928 T ss_pred HHHHHHHHHHHHHCCCCCHHHHHHhcc----------CCccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccCCC
929 Confidence 999999999999999999999997654 2334445666778889999999999999987554432 13334
930
931
932 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
933 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
934 +-+|+|++|++|++-|..+|.+..|+...+..++++.++.+.+...++|+-++++|-++|+..+..+||++++...+..
935 T Consensus 236 ~~~p~~l~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~w~~~~~~~~~~- 314 (598)
936 T 4ASR_A 236 GPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTD- 314 (598)
937 T ss_dssp SCEEGGGSSSTTSSCCGGGHHHHCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSS-
938 T ss_pred CCCcHHHccccchhcchhhhhhcCCCCCCCCCCccHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChHHhhhhhccCCCC-
939 Confidence 6689999999999999999999999987776677777878888889999999999999999988889999998765432
940
941
942 Q sp|Q9BYF1|ACE2 340 QK-AVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKH 417 (805)
943 Q Consensus 340 qk-avchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkh 417 (805)
944 .| ..|||.++++.. ++.||++|+..+.+|+.|.+||+||..+.+.+..+|++.+.+.+.+|+|+++++|++.+.+|.+
945 T Consensus 315 ~k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~d~~E~~s~~~e~~~~~~~~ 394 (598)
946 T 4ASR_A 315 GRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKH 394 (598)
947 T ss_dssp SCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHHTTSCGGGSSCSSHHHHHHHHHHHHHHHTSHHH
948 T ss_pred CCCCcccchhhhccCCCCEEEEecCCCCHHHHHHHHHHHHHHHHHHHccCCChHHccCCChHHHHHHHHHHHHHhcCHHH
949 Confidence 22 368888888875 5899999999999999999999999999999988999999889999999999999999999999
950
951
952 Q sp|Q9BYF1|ACE2 418 LKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
953 Q Consensus 418 lksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
954 |+.++++. ..+...+..++.++++++..+..+|+..+...|++-++.|++..+.+.+.||+...+..|+..|.+.++..
955 T Consensus 395 L~~~~~~~-~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~l~~~~~g~~~~~~~~~~~ 473 (598)
956 T 4ASR_A 395 LEKIGLLK-DYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKD 473 (598)
957 T ss_dssp HHHTTSSC-SCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTCSCGGGHHHHHHHHCCCCCCEECSSCEETTC
958 T ss_pred HHHcCCCC-ccCCChHHHHHHHHHHHHHHhhhhHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCChhh
959 Confidence 99999864 33334455678888999999999999888899999999998877889999999999998987665555555
960
961
962 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALE 571 (805)
963 Q Consensus 498 cdpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlale 571 (805)
964 .+|.+..|+..+..+..|....+..+|+-+.+|+.+.+ +||+|.|+...+.++|.++-++|..|.+.||.-.++
965 T Consensus 474 ~~~~~~~h~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~l~~G~s~~~~el~~ 553 (598)
966 T 4ASR_A 474 FDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALE 553 (598)
967 T ss_dssp CCGGGSHHHHTTCCSHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHH
968 T ss_pred CCCccceeecCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHH
969 Confidence 56777778765555788888888999999999887554 689999999988999999999999999999999999
970
971
972 Q sp|Q9BYF1|ACE2 572 NVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGWSTDWS 611 (805)
973 Q Consensus 572 nvvgaknmnvrpllnyfeplftwlkdqnkns--fvgwstdws 611 (805)
974 ...|..-.+..+++.+|+|+-.||+.+|+.. -+||.++|-
975 T Consensus 554 ~~~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~ 595 (598)
976 T 4ASR_A 554 AFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNK 595 (598)
977 T ss_dssp HHHSCCSCCSHHHHHHHHHHHHHHHHHHHHTTCCCSCCCCCS
978 T ss_pred HHhCCCCCChHHHHHHHHHHHHHHHHhhhhcCccccccCCCc
979 Confidence 9999988899999999999999999988755 499999884
980
981
982 No 11
983 >4CA7_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1); HYDROLASE, ZINC METALLOPEPTIDASE, INHIBITOR BINDING; HET: MAN, NAG, 3EF, BMA; 1.82A {DROSOPHILA MELANOGASTER}
984 Probab=100.00 E-value=3.2e-56 Score=426.00 Aligned_cols=578 Identities=37% Similarity=0.724 Sum_probs=485.3 Template_Neff=10.200
985
986 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
987 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
988 +.+...||..++.....+-....++.|.++++.+++..+..+.+..+.+.+..+..+.+..|.++...+-..+-+|+.+.
989 T Consensus 6 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 85 (598)
990 T 4CA7_A 6 EIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALT 85 (598)
991 T ss_dssp GC-CHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCHHHHHHHHHHH
992 T ss_pred HHHHHHHHHHHHHHHHHHhCHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHhcchhcchhcCCCHHHHHHHHHHH
993 Confidence 46678899999999999999999999999999999988888788888888888777666555533333334555666666
994
995
996 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDN-PQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY 180 (805)
997 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdn-pqeclllepglneimansldynerlwaweswrsevgkqlrply 180 (805)
998 ..+...|+++.-++++..+..+..+|++...|.... ..+++.+.|.+..+|.++-|...|--+|++|++..+..+.+++
999 T Consensus 86 ~~~~~~L~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~~~~~R~~~~~~~~~~~~~~~~~~l 165 (598)
1000 T 4CA7_A 86 KLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQF 165 (598)
1001 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCEECCSSCTTCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHHH
1002 T ss_pred HhccccCCHHHHHHHHHHHHHHHHHhhccccCCCCCCCCccccCCHHHHHHHHcCCCHHHHHHHHHHHHHHhcHHHHHHH
1003 Confidence 666678888888888888899999999887776432 1255566788999999999999999999999988778899999
1004
1005
1006 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPI 259 (805)
1007 Q Consensus 181 eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispi 259 (805)
1008 .+.+-+++++|+...|.+|.+|+..++ +...+.+-++..++.++|+++.+|+|+|.++...|.. .+++-
1009 T Consensus 166 ~~lv~~r~~~A~~~Gy~s~~~~~l~~~----------~~~~v~~~l~~l~~~i~~~~~~l~~~~~~~~~~~~~~~~~~~~ 235 (598)
1010 T 4CA7_A 166 ERYVELNTKAAKLNNFTSGAEAWLDEY----------EDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSET 235 (598)
1011 T ss_dssp HHHHHHHHHHHHHTTCSSHHHHHHGGG----------CCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCSS
1012 T ss_pred HHHHHHHHHHHHHCCCCCHHHHHHhcc----------CCccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccCCC
1013 Confidence 999999999999999999999997654 2334445666778889999999999999987554432 13334
1014
1015
1016 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
1017 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
1018 +-+|+|++|++|++-|..+|.+..|+...+..++++.++.+.+...++|+-++++|-++|+..+..+||++++...+..
1019 T Consensus 236 ~~~p~~l~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~w~~~~~~~~~~- 314 (598)
1020 T 4CA7_A 236 GPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTD- 314 (598)
1021 T ss_dssp SCEEGGGSSSTTCSCCGGGHHHHCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCCS-
1022 T ss_pred CCCcHHHccccchhcchhhhhhcCCCCCCCCCCccHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChHHhhhhhccCCCC-
1023 Confidence 6689999999999999999999999987776677777878888889999999999999999988889999998765432
1024
1025
1026 Q sp|Q9BYF1|ACE2 340 QK-AVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKH 417 (805)
1027 Q Consensus 340 qk-avchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkh 417 (805)
1028 .| ..|||.++++.. ++.||++|+..+.+|+.|.+||+||..+.+.+..+|++.+.+.+.+|+|+++++|++.+.+|.+
1029 T Consensus 315 ~k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~d~~E~~s~~~e~~~~~~~~ 394 (598)
1030 T 4CA7_A 315 GRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKH 394 (598)
1031 T ss_dssp SCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHH
1032 T ss_pred CCCCcccchhhhccCCCCEEEEecCCCCHHHHHHHHHHHHHHHHHHHccCCChHHccCCChHHHHHHHHHHHHHhcCHHH
1033 Confidence 22 368888888875 5899999999999999999999999999999988999999889999999999999999999999
1034
1035
1036 Q sp|Q9BYF1|ACE2 418 LKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
1037 Q Consensus 418 lksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
1038 |+.++++. ..+...+..++.++++++..+..+|+..+...|++-++.|++..+.+.+.||+...+..|+..|.+.++..
1039 T Consensus 395 L~~~~~~~-~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~l~~~~~g~~~~~~~~~~~ 473 (598)
1040 T 4CA7_A 395 LEKIGLLK-DYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKD 473 (598)
1041 T ss_dssp HHHTTCSC-SCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTCSCGGGHHHHHHHHCCCCCCEECSSCEETTC
1042 T ss_pred HHHcCCCC-ccCCChHHHHHHHHHHHHHHhhhhHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCChhh
1043 Confidence 99999864 33334455678888999999999999888899999999998877889999999999998987665555555
1044
1045
1046 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALE 571 (805)
1047 Q Consensus 498 cdpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlale 571 (805)
1048 .+|.+..|+..+..+..|....+..+|+-+.+|+.+.+ +||+|.|+...+.++|.++-++|..|.+.||.-.++
1049 T Consensus 474 ~~~~~~~h~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~l~~G~s~~~~el~~ 553 (598)
1050 T 4CA7_A 474 FDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALE 553 (598)
1051 T ss_dssp CCGGGSHHHHTTCCCHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHH
1052 T ss_pred CCCccceeecCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHH
1053 Confidence 56777778765555788888888999999999887554 689999999988999999999999999999999999
1054
1055
1056 Q sp|Q9BYF1|ACE2 572 NVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGWSTDWS 611 (805)
1057 Q Consensus 572 nvvgaknmnvrpllnyfeplftwlkdqnkns--fvgwstdws 611 (805)
1058 ...|..-.+..+++.+|+|+-.||+.+|+.. -+||.++|-
1059 T Consensus 554 ~~~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~ 595 (598)
1060 T 4CA7_A 554 AFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNK 595 (598)
1061 T ss_dssp HHHSCCSCCTHHHHHHHHHHHHHHHHHHHHTTCCCSCCCCCS
1062 T ss_pred HHhCCCCCChHHHHHHHHHHHHHHHHhhhhcCccccccCCCc
1063 Confidence 9999988899999999999999999988755 499999884
1064
1065
1066 No 12
1067 >2C6F_A ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM (E.C.3.4.15.1); HYDROLASE, ANGIOTENSIN-I CONVERTING ENZYME, N; HET: ACT, GOL, NAG; 3.01A {HOMO SAPIENS}
1068 Probab=100.00 E-value=2.3e-52 Score=400.71 Aligned_cols=579 Identities=43% Similarity=0.828 Sum_probs=477.2 Template_Neff=10.200
1069
1070 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMY-P--LQEIQNLTVKLQLQ 98 (805)
1071 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmy-p--lqeiqnltvklqlq 98 (805)
1072 +++...|+++++.....+--..+.+.|.++++++++..+....+..+.+.|..+.+....-. . +++...-..+-.|+
1073 T Consensus 14 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~d~~~~~~~~~~~~~~~~~~~~~~l~~~~~~l~~~~~~~~~~~~~~~~l~ 93 (612)
1074 T 2C6F_A 14 EAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIG 93 (612)
1075 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTSCSCHHHHHHHH
1076 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcchHhhCCCHHHHHHHH
1077 Confidence 46677899999999999999999999999999998877666666666666655444321110 0 11111112233344
1078
1079
1080 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRP 178 (805)
1081 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrp 178 (805)
1082 .+...+...|+++..+++..+...++.+|++-.+|..+.+.+|+.+.+.+..+|.++-|...|--+|++|+...+..+.+
1083 T Consensus 94 ~l~~~~~~~L~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~ 173 (612)
1084 T 2C6F_A 94 AVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKP 173 (612)
1085 T ss_dssp HHSCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEECCSSCCCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
1086 T ss_pred HHHHhhcccCCHHHHHHHHHHHHHHHHHHHhccccCCCCCCCcccCChhHHHHHhhCCCHHHHHHHHHHHHHHhCcccHH
1087 Confidence 45455556788887777888888999999999988777666788888899999999999999999999999877788999
1088
1089
1090 Q sp|Q9BYF1|ACE2 179 LYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YIS 257 (805)
1091 Q Consensus 179 lyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yis 257 (805)
1092 ++.+.+-+++++|+...|++|.+|+..++.. ....+-++...+.++|++..+|+|++.++...+-. .++
1093 T Consensus 174 ~l~~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~g~~~~~ 243 (612)
1094 T 2C6F_A 174 LYEDFTALSNEAYKQDGFTDTGAYWRSWYNS----------PTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYIN 243 (612)
1095 T ss_dssp HHHHHHHHHHHHHHTTTCSSHHHHHHGGGCC----------TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTCC
1096 T ss_pred HHHHHHHHHHHHHHHcCCCCHHHHHHHhhCC----------CcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccC
1097 Confidence 9999999999999999999999999776542 23345566777888999999999999987554321 233
1098
1099
1100 Q sp|Q9BYF1|ACE2 258 PIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPG 337 (805)
1101 Q Consensus 258 pigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpg 337 (805)
1102 .-+-+|.|++|++|+..|+.+|...+|+.++...++++++....+...++++.++++|-++|+..+...+|+++....||
1103 T Consensus 244 ~~~~lp~d~~~~~~~~~~~~~~~~~~p~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~~~~r~~ 323 (612)
1104 T 2C6F_A 244 LRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPA 323 (612)
1105 T ss_dssp TTSCEETTSSSSTTCSCCGGGHHHHCSSCSSCCSCTHHHHHHHTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCS
1106 T ss_pred CCCCCcHHHccCcchhcchhhhhhhCCCCCCCCCCCcHHHHhCCCCHHHHHHHHHHHHHhcCCCCCChhhhccccccCCC
1107 Confidence 34456999999999999999999999998777677778877777888899999999999999998888999999877777
1108
1109
1110 Q sp|Q9BYF1|ACE2 338 NVQKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPK 416 (805)
1111 Q Consensus 338 nvqkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpk 416 (805)
1112 .-....||+.++++.. ++.||++|...+.+|+.|.+||+||..+.+.+..+|++.++.++.+|+|+++++|+..+.+|.
1113 T Consensus 324 K~~~~~~~a~~~~~~~~~~~~i~~~~~~~~~~~~tl~HElGHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~ 403 (612)
1114 T 2C6F_A 324 DGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPE 403 (612)
1115 T ss_dssp SSCCCCCSCEEEECSSSSCEEEECCCCSCHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCSSHHHHHHHHHHHHHHHHSHH
1116 T ss_pred CCCcceecchhhhCcCCCcEEEEEcCCCCHHHHHHHHHHHHHHHHHHHccCCCHHHccCCChHHHHHHHHHHHHHhcCHH
1117 Confidence 6655678888887764 689999999999999999999999999999988899998888889999999999999999999
1118
1119
1120 Q sp|Q9BYF1|ACE2 417 HLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDET 496 (805)
1121 Q Consensus 417 hlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdet 496 (805)
1122 .|+.++++.. .+...+..++.++++++..+..+|+..+++.|+|.++.|.++.+.+-+.||+...+..|...|.+.+++
1123 T Consensus 404 ~L~~~~~~~~-~~~~~~~~~~~l~~~~l~~l~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~l~~~y~g~~~~~~~~~~ 482 (612)
1124 T 2C6F_A 404 HLHKIGLLDR-VTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNET 482 (612)
1125 T ss_dssp HHHHTTSCCC-CCCSHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTSSCGGGHHHHHHHHHHHHHCEECSSCCCTT
1126 T ss_pred HHHHcCCCCC-CCCCcHHHHHHHHHHHHHHhhccHHHHHHHHHHHHHhcCCCChhhHHHHHHHHHHHHcCCCCCCCCChh
1127 Confidence 9999988753 222234456788899999999999999999999999999888888999999988888887655555666
1128
1129
1130 Q sp|Q9BYF1|ACE2 497 YCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGA 576 (805)
1131 Q Consensus 497 ycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvga 576 (805)
1132 ..||++..|+..+...+.|....+..+|+-+.+|+...+.+|+|+||+..+.++|+++.++|+.|.+.+|.-.++...|.
1133 T Consensus 483 ~~~~~~~~h~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~L~~G~s~~~~el~~~~~G~ 562 (612)
1134 T 2C6F_A 483 HFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGL 562 (612)
1135 T ss_dssp CCGGGGSTTTTTTCCCHHHHHHHHHHHHHHHHHHHHHTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSC
1136 T ss_pred cCCcccceecCCChhhHHHHHHHHHHHHHHHHHHHHcCCCCChhhCCccCCHHHHHHHHHHHhcCCCCCHHHHHHHHhCC
1137 Confidence 67788888876434467888888999999999999878889999999999999999999999999999999999999998
1138
1139
1140 Q sp|Q9BYF1|ACE2 577 KNMNVRPLLNYFEPLFTWLKDQNKNSF--VGWSTDWS 611 (805)
1141 Q Consensus 577 knmnvrpllnyfeplftwlkdqnknsf--vgwstdws 611 (805)
1142 ...+..+++.+|+++..||+.+|++.- +||..+|-
1143 T Consensus 563 d~~~~~~~~~~~~~l~~~l~~~~~~~~~~~g~~~~~~ 599 (612)
1144 T 2C6F_A 563 DALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQW 599 (612)
1145 T ss_dssp SSCCSHHHHHHSHHHHHHHHHHHHHTTCCSSCSSTTC
1146 T ss_pred CCCCcHHHHHHHHHHHHHHHHHHHhcCCccCCCccCC
1147 Confidence 778889999999999999999988665 99997663
1148
1149
1150 No 13
1151 >5GIV_E Carboxypeptidase; M32 carboxypeptidase, Cobalt, Metallopeptidase, HYDROLASE; 2.4A {Deinococcus radiodurans str. R1}
1152 Probab=100.00 E-value=4.3e-52 Score=399.56 Aligned_cols=474 Identities=18% Similarity=0.185 Sum_probs=379.1 Template_Neff=9.400
1153
1154 Q sp|Q9BYF1|ACE2 19 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 98 (805)
1155 Q Consensus 19 stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlq 98 (805)
1156 ++.+..+.+||.+.+.+...+-++.++++|++.|++++++.+.....- ++|++. ..+.+.+-.++-+|.
1157 T Consensus 3 ~~~~~~~~~~L~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~~~~~~----------~~l~~~-~~~~~~~~~~~~~l~ 71 (503)
1158 T 5GIV_E 3 TTRQDTQWQQLTEHWQELADFGGIEALLGWDQSTFLPAGAAEDRARQQ----------SLLAGL-RHARATDAGYGKLLD 71 (503)
1159 T ss_dssp ----CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHH----------HHHHHH-HHHHHSCHHHHHHHH
1160 T ss_pred ccchHHHHHHHHHHHHHHHHHhcHHHHHHHHHHcCCCcchHHHHHHHH----------HHHHHH-HHHhhcCHHHHHHHH
1161 Confidence 567788999999999999999999999999999999998876544333 233332 133455666777777
1162
1163
1164 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG-KQLR 177 (805)
1165 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg-kqlr 177 (805)
1166 .++.. +.++++. ..++..|..+|..++ .++|.+.++|+++.+..+ ++|..||.+.+ +.++
1167 T Consensus 72 ~l~~~--~~l~~~~----~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~ 132 (503)
1168 T 5GIV_E 72 AASSR--SDLSPEQ----ARMVQVARQDFEKAT-----------RIPAEFVREFSGHVGQSY--SAWTEARPANDFGRMV 132 (503)
1169 T ss_dssp HHHTC--SSCCHHH----HHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHTTTTCHHHHH
1170 T ss_pred HHhcC--CCCCHHH----HHHHHHHHHHHHHhc-----------CCCHHHHHHHHhchhhHH--HHHHHHHHhCChhHhH
1171 Confidence 77655 2344433 344677888887765 467899999999998876 89999999977 8999
1172
1173
1174 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYE-DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1175 Q Consensus 178 plyeeyvvlknemaranhye-dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1176 |+|+++|-|+|+.|+.+.|+ ++.|||...|+- |...++++..|++|+|+|..||++||.+-
1177 T Consensus 133 ~~~~~~v~l~~~~A~~~g~~~~~yd~~l~~ye~----------~~~~~~l~~l~~~i~~~~~~l~~~v~~~~-------- 194 (503)
1178 T 5GIV_E 133 PYLEKTLDLSLQAASYFPEFGDPLDYYINESDE----------GMTAEQVGQVFAELRAALVPLADAVIAAG-------- 194 (503)
1179 T ss_dssp HHHHHHHHHHHHHHHTCTTCSSHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHHHC--------
1180 T ss_pred HHHHHHHHHHHHHHhhCCCCCCHHHHHHHhcCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHHcC--------
1181 Confidence 99999999999999999998 999999876653 44568899999999999999999999851
1182
1183
1184 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1185 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1186 .|+ | .+..+.++..++++.+++||.++|++... +. .|
1187 T Consensus 195 ~~~---~--------------------------------~~~~~~~~~~~~~~~~~~~~~~lG~~~~~------~~-~d- 231 (503)
1188 T 5GIV_E 195 APR---T--------------------------------DFLGRGFAQERQLAFGERVIRDYGYDFRR------GR-QD- 231 (503)
1189 T ss_dssp CCC---C--------------------------------GGGGSCCCHHHHHHHHHHHHHHHTCCGGG------CC-EE-
1190 T ss_pred CCC---c--------------------------------hhhcCCCCHHHHHHHHHHHHHHhCCCccc------Cc-cc-
1191 Confidence 010 1 12334455677889999999999998621 11 11
1192
1193
1194 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAAQ--PFLLRNGANEGFHEAVGEIMSLSA 412 (805)
1195 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaaq--pfllrnganegfheavgeimslsa 412 (805)
1196 ..|||.+|+++.+|+||.||.+++ ++|+.+.|||+||++|.+.+..+ +..++.+++.+|||+++..|.+..
1197 T Consensus 232 -----~~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~ 306 (503)
1198 T 5GIV_E 232 -----LTHHPFMTRLGGHDVRITTRVKEQDPTDALYSTLHEAGHALYEQGVDAAFLGTPLGGGVSAGVHESQSRLWENLV 306 (503)
1199 T ss_dssp -----ECSSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHHTSCTTTTTSTTSSCSCHHHHHHHHHCCCCCC
1200 T ss_pred -----cCCCccccCCCCCcEEEEeecCCCChHHHHHHHHHHHHHHHHHcCCCHHHcCCCCCCccchHHHHHHHHHHHHhh
1201 Confidence 599999999988999999999999 69999999999999999988764 345578899999999999999999
1202
1203
1204 Q sp|Q9BYF1|ACE2 413 AT---------PKHLKSIGLLSPDF-QEDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWW 478 (805)
1205 Q Consensus 413 at---------pkhlksigllspdf-qednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkww 478 (805)
1206 .+ |++++.+|.+-.+. .++-...+| .+++.++.-+-.+|+.++..+|+|-+|.|+++.+++.+.||
1207 T Consensus 307 ~~~~~f~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~g~~~~~~l~~~w~ 386 (503)
1208 T 5GIV_E 307 GRSRAFWAAYFGDWRDTFPEQLAGVTEEEMYRAVNTVSRSLIRTDADELTYNLHVITRFELEREMLAGKLAVRDLADAWH 386 (503)
1209 T ss_dssp TTSHHHHHHHHHHHHHHSTTTTTTCCHHHHHHHTTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHTTSSCGGGHHHHHH
1210 T ss_pred cCCHHHHHHHHHHHHHHCcHHhCCCCHHHHHHHHHhhCHHHhHHHhhhhhhcHHHHHHHHHHHHHhcCCCCHHHHHHHHH
1211 Confidence 99 99999988542222 222333444 45677777778888899999999999999999999999999
1212
1213
1214 Q sp|Q9BYF1|ACE2 479 EMKREIVGVVEPVPHDETYCDPASLFHVSNDY---SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN--STEAGQK 553 (805)
1215 Q Consensus 479 emkreivgvvepvphdetycdpaslfhvsndy---sfiryytrtlyqfqfqealcqaakhegplhkcdisn--steagqk 553 (805)
1216 ++.++..|+..|. +...|+ ...|++.++ .|++|....++++|+.+++|+... .+|+| +.+ ..++|..
1217 T Consensus 387 ~~~~~y~G~~~~~--~~~~~~--~~~h~~~~~~~~y~~~Y~~g~i~a~ql~~~~~~~~~---~~~~~-~~~~~~~~~~~~ 458 (503)
1218 T 5GIV_E 387 AAYEQNLGLRAPS--DVDGAL--QDVHWYFGPIGGSFQGYTIGNVLSAQFYAAAEAANP---GLEAD-FARKDFSRLHGW 458 (503)
1219 T ss_dssp HHHHHHHSCCCSS--STTTTT--SCSGGGSSCSSSSSHHHHHHHHHHHHHHHHHHHHST---THHHH-HHTTCCHHHHHH
1220 T ss_pred HHHHHHhCCCCCC--CCCCCc--ccccccccCcccCCHHHHHHHHHHHHHHHHHHHhCC---ChHHH-hhcCChHHHHHH
1221 Confidence 9999999987553 334454 467888765 479999999999999999998764 49999 863 4688999
1222
1223
1224 Q sp|Q9BYF1|ACE2 554 LF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1225 Q Consensus 554 lf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1226 |- ++++.|.+.||.-.++.+.|. .++..++++||+|+++||-+
1227 T Consensus 459 l~~~il~~G~~~~~~ell~~~~g~-~ls~~~~l~y~~~~~~~~~~ 502 (503)
1228 T 5GIV_E 459 LRENVYRHGRRWTPGELIERATGQ-ALTAGPYLKYLRGKYGELYG 502 (503)
1229 T ss_dssp HCCCCCTTTTSSCHHHHHHHHHSS-SSCSHHHHHHHHHHHHHHHC
1230 T ss_pred HHHchHhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1231 Confidence 94 999999999999999999996 89999999999999999864
1232
1233
1234 No 14
1235 >5GIV_F Carboxypeptidase; M32 carboxypeptidase, Cobalt, Metallopeptidase, HYDROLASE; 2.4A {Deinococcus radiodurans str. R1}
1236 Probab=100.00 E-value=4.3e-52 Score=399.56 Aligned_cols=474 Identities=18% Similarity=0.185 Sum_probs=381.7 Template_Neff=9.400
1237
1238 Q sp|Q9BYF1|ACE2 19 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 98 (805)
1239 Q Consensus 19 stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlq 98 (805)
1240 ++.+..+.+||.+.+.+...+-++.++++|++.|++++++.+.....- ++|++. ..+.+.+-.++-+|.
1241 T Consensus 3 ~~~~~~~~~~L~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~~~~~~----------~~l~~~-~~~~~~~~~~~~~l~ 71 (503)
1242 T 5GIV_F 3 TTRQDTQWQQLTEHWQELADFGGIEALLGWDQSTFLPAGAAEDRARQQ----------SLLAGL-RHARATDAGYGKLLD 71 (503)
1243 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHH----------HHHHHH-HHHHHTCHHHHHHHH
1244 T ss_pred ccchHHHHHHHHHHHHHHHHHhcHHHHHHHHHHcCCCcchHHHHHHHH----------HHHHHH-HHHhhcCHHHHHHHH
1245 Confidence 567788999999999999999999999999999999998876544333 233332 133455666777777
1246
1247
1248 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG-KQLR 177 (805)
1249 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg-kqlr 177 (805)
1250 .++.. +.++++. ..++..|..+|..++ .++|.+.++|+++.+..+ ++|..||.+.+ +.++
1251 T Consensus 72 ~l~~~--~~l~~~~----~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~ 132 (503)
1252 T 5GIV_F 72 AASSR--SDLSPEQ----ARMVQVARQDFEKAT-----------RIPAEFVREFSGHVGQSY--SAWTEARPANDFGRMV 132 (503)
1253 T ss_dssp HHHHC--SCCCHHH----HHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHTTTTCHHHHH
1254 T ss_pred HHhcC--CCCCHHH----HHHHHHHHHHHHHhc-----------CCCHHHHHHHHhchhhHH--HHHHHHHHhCChhHhH
1255 Confidence 77655 2344433 344677888887765 467899999999998876 89999999977 8999
1256
1257
1258 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYE-DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1259 Q Consensus 178 plyeeyvvlknemaranhye-dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1260 |+|+++|-|+|+.|+.+.|+ ++.|||...|+- |...++++..|++|+|+|..||++||.+-
1261 T Consensus 133 ~~~~~~v~l~~~~A~~~g~~~~~yd~~l~~ye~----------~~~~~~l~~l~~~i~~~~~~l~~~v~~~~-------- 194 (503)
1262 T 5GIV_F 133 PYLEKTLDLSLQAASYFPEFGDPLDYYINESDE----------GMTAEQVGQVFAELRAALVPLADAVIAAG-------- 194 (503)
1263 T ss_dssp HHHHHHHHHHHHHHHTCTTSSSHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHHHC--------
1264 T ss_pred HHHHHHHHHHHHHHhhCCCCCCHHHHHHHhcCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHHcC--------
1265 Confidence 99999999999999999998 999999876653 44568899999999999999999999851
1266
1267
1268 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1269 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1270 .|+ | .+..+.++..++++.+++||.++|++... +. .|
1271 T Consensus 195 ~~~---~--------------------------------~~~~~~~~~~~~~~~~~~~~~~lG~~~~~------~~-~d- 231 (503)
1272 T 5GIV_F 195 APR---T--------------------------------DFLGRGFAQERQLAFGERVIRDYGYDFRR------GR-QD- 231 (503)
1273 T ss_dssp CCC---C--------------------------------GGGGSCCCHHHHHHHHHHHHHHHTCCTTS------CC-EE-
1274 T ss_pred CCC---c--------------------------------hhhcCCCCHHHHHHHHHHHHHHhCCCccc------Cc-cc-
1275 Confidence 010 1 12334455677889999999999998621 11 11
1276
1277
1278 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAAQ--PFLLRNGANEGFHEAVGEIMSLSA 412 (805)
1279 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaaq--pfllrnganegfheavgeimslsa 412 (805)
1280 ..|||.+|+++.+|+||.||.+++ ++|+.+.|||+||++|.+.+..+ +..++.+++.+|||+++..|.+..
1281 T Consensus 232 -----~~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~ 306 (503)
1282 T 5GIV_F 232 -----LTHHPFMTRLGGHDVRITTRVKEQDPTDALYSTLHEAGHALYEQGVDAAFLGTPLGGGVSAGVHESQSRLWENLV 306 (503)
1283 T ss_dssp -----ECSSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHHHSCGGGTTSTTSSCSCHHHHHHHHHCCCCCC
1284 T ss_pred -----cCCCccccCCCCCcEEEEeecCCCChHHHHHHHHHHHHHHHHHcCCCHHHcCCCCCCccchHHHHHHHHHHHHhh
1285 Confidence 599999999988999999999999 69999999999999999988764 345578899999999999999999
1286
1287
1288 Q sp|Q9BYF1|ACE2 413 AT---------PKHLKSIGLLSPDF-QEDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWW 478 (805)
1289 Q Consensus 413 at---------pkhlksigllspdf-qednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkww 478 (805)
1290 .+ |++++.+|.+-.+. .++-...+| .+++.++.-+-.+|+.++..+|+|-+|.|+++.+++.+.||
1291 T Consensus 307 ~~~~~f~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~g~~~~~~l~~~w~ 386 (503)
1292 T 5GIV_F 307 GRSRAFWAAYFGDWRDTFPEQLAGVTEEEMYRAVNTVSRSLIRTDADELTYNLHVITRFELEREMLAGKLAVRDLADAWH 386 (503)
1293 T ss_dssp TTSHHHHHHHHHHHHHHSHHHHTTCCHHHHHHHTTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHTTSSCGGGHHHHHH
1294 T ss_pred cCCHHHHHHHHHHHHHHCcHHhCCCCHHHHHHHHHhhCHHHhHHHhhhhhhcHHHHHHHHHHHHHhcCCCCHHHHHHHHH
1295 Confidence 99 99999988542222 222333444 45677777778888899999999999999999999999999
1296
1297
1298 Q sp|Q9BYF1|ACE2 479 EMKREIVGVVEPVPHDETYCDPASLFHVSNDY---SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN--STEAGQK 553 (805)
1299 Q Consensus 479 emkreivgvvepvphdetycdpaslfhvsndy---sfiryytrtlyqfqfqealcqaakhegplhkcdisn--steagqk 553 (805)
1300 ++.++..|+..|. +...|+ ...|++.++ .|++|....++++|+.+++|+... .+|+| +.+ ..++|..
1301 T Consensus 387 ~~~~~y~G~~~~~--~~~~~~--~~~h~~~~~~~~y~~~Y~~g~i~a~ql~~~~~~~~~---~~~~~-~~~~~~~~~~~~ 458 (503)
1302 T 5GIV_F 387 AAYEQNLGLRAPS--DVDGAL--QDVHWYFGPIGGSFQGYTIGNVLSAQFYAAAEAANP---GLEAD-FARKDFSRLHGW 458 (503)
1303 T ss_dssp HHHHHHHSCCCSS--STTTTT--SCSGGGSSCSSSSSHHHHHHHHHHHHHHHHHHHHST---THHHH-HHTTCCHHHHHH
1304 T ss_pred HHHHHHhCCCCCC--CCCCCc--ccccccccCcccCCHHHHHHHHHHHHHHHHHHHhCC---ChHHH-hhcCChHHHHHH
1305 Confidence 9999999987553 334454 467888765 479999999999999999998764 49999 863 4688999
1306
1307
1308 Q sp|Q9BYF1|ACE2 554 LF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1309 Q Consensus 554 lf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1310 |- ++++.|.+.||.-.++.+.|. .++..++++||+|+++||-+
1311 T Consensus 459 l~~~il~~G~~~~~~ell~~~~g~-~ls~~~~l~y~~~~~~~~~~ 502 (503)
1312 T 5GIV_F 459 LRENVYRHGRRWTPGELIERATGQ-ALTAGPYLKYLRGKYGELYG 502 (503)
1313 T ss_dssp HCCCCCTTTTSSCHHHHHHHHHSS-SCCSHHHHHHHHHHHHHHHC
1314 T ss_pred HHHchHhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1315 Confidence 94 999999999999999999996 89999999999999999864
1316
1317
1318 No 15
1319 >3HQ2_B Bacillus subtilis M32 carboxypeptidase (E.C.3.4.24.-); Hydrolase, Metal-binding, Metalloprotease, Protease; HET: PO4; 2.9A {Bacillus subtilis}
1320 Probab=100.00 E-value=1.1e-47 Score=361.19 Aligned_cols=473 Identities=16% Similarity=0.152 Sum_probs=365.7 Template_Neff=10.100
1321
1322 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
1323 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
1324 ++-|++||.+++.++.++.+.+++++|+|.||+|+++.+........ |+.. -.+.+++-.++-+|+.++
1325 T Consensus 3 ~~~a~~~L~~~~~~~~~~~~~~~~~~Wd~~T~~p~~~~~~~~~~~~~----------l~~~-~~~~~~~~~~~r~l~~l~ 71 (501)
1326 T 3HQ2_B 3 IHTYEKEFFDLLKRISHYSEAVALMHWDSRTGAPKNGSEDRAESIGQ----------LSTD-IFNIQTSDRMKELIDVLY 71 (501)
1327 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTCCGGGHHHHHHHHHH----------HHHH-HHHHHHCHHHHHHHHHHH
1328 T ss_pred cchHHHHHHHHHHHHHhHHHHHHHHHHHHHhCCCCCChHHHHHHHHH----------HHHH-HHHHhcCHHHHHHHHHHH
1329 Confidence 45689999999999999999999999999999999887654433322 2222 234667788899999998
1330
1331
1332 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLRPL 179 (805)
1333 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlrpl 179 (805)
1334 ..|. .|+++.. ..++.|..+|+.++ |- .|.+-+.++++ .++|.++|+.||.. + +.++|+
1335 T Consensus 72 ~~~~-~l~~~~~----~~~~~~~~~~~~~~-~~----------~~~~~~~~~~~--~~~r~~~w~~~~~~-~~~~~~~~~ 132 (501)
1336 T 3HQ2_B 72 ERFD-DLSEDTK----KAVELAKKEYEENK-KI----------PEAEYKEYVIL--CSKAETAWEEAKGK-SDFSLFSPY 132 (501)
1337 T ss_dssp HTGG-GSCHHHH----HHHHHHHHHHHHHH-TS----------CHHHHHHHHHH--HHHHHHHHHHHHHH-TCHHHHHHH
1338 T ss_pred Hccc-CCCHHHH----HHHHHHHHHHHHcc-CC----------CHHHHHHHHHH--HHHHHHHHHHHHhc-CCHHHhHHH
1339 Confidence 8775 4665542 25788888898764 32 24444455544 45999999999986 6 789999
1340
1341
1342 Q sp|Q9BYF1|ACE2 180 YEEYVVLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISP 258 (805)
1343 Q Consensus 180 yeeyvvlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp 258 (805)
1344 +.++|-+++++|+.+.|++ ..|+|...|+- +.-.++++..|++|+|.|..+|+++|.|...
1345 T Consensus 133 l~~lv~l~~~~A~~~Gy~~~~~~~~~~~~~~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~~~-------- 194 (501)
1346 T 3HQ2_B 133 LEQLIEFNKRFITYWGYQEHPYDALLDLFEP----------GVTVKVLDQLFAELKEAIIPLVKQVTASGNK-------- 194 (501)
1347 T ss_dssp HHHHHHHHHHHHHHHCCSSCTTHHHHTTTST----------TCCHHHHHHHHHHHHHHHHHHHHHHHSCSCC--------
1348 T ss_pred HHHHHHHHHHHHHHccCCCChHHHHHHhhCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHHcCCC--------
1349 Confidence 9999999999999999995 49999887762 2335789999999999999999999986310
1350
1351
1352 Q sp|Q9BYF1|ACE2 259 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 338 (805)
1353 Q Consensus 259 igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgn 338 (805)
1354 | | +.+..+.+...++++.++.+|.+.|++.. .|
1355 T Consensus 195 ----p-----------~-------------------~~~~~~~~~~~~~~~~~~~~~~~~G~~~~-~~------------ 227 (501)
1356 T 3HQ2_B 195 ----P-----------D-------------------TSFITKAFPKEKQKELSLYFLQELGYDFD-GG------------ 227 (501)
1357 T ss_dssp ----C-----------C-------------------CTTTTSCCCHHHHHHHHHHHHHHHTCCGG-GC------------
1358 T ss_pred ----C-----------C-------------------cchhcCcCCHHHHHHHHHHHHHHhCCCCC-CC------------
1359 Confidence 1 0 11233445556678889999999998752 11
1360
1361
1362 Q sp|Q9BYF1|ACE2 339 VQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAYA-AQPF-LLRNGANEGFHEAVGEIMSLS-AA 413 (805)
1363 Q Consensus 339 vqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmaya-aqpf-llrnganegfheavgeimsls-aa 413 (805)
1364 .....|||.+|+++.+|+||.+|.. ..++|+.+.|||+||++|.+.+. .+|+ .++.+++.+|||+++..|.+. +.
1365 T Consensus 228 r~~k~~~~~~~~~~~~d~ri~~~~~~~~~~~~~~tl~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~~~ 307 (501)
1366 T 3HQ2_B 228 RLDETVHPFATTLNRGDVRVTTRYDEKDFRTAIFGTIHECGHAIYEQNIDEALSGTNLSDGASMGIHESQSLFYENFIGR 307 (501)
1367 T ss_dssp CEEECSSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHTTSCGGGTTSTTCSCSCHHHHHHHHHHHCCCCCT
1368 T ss_pred CCCCCCCceeecCCCCceEEEEecChhhHHHHHHHHHHHHHHHHHHcCCCHHHCCCCccccccchhHHHHHHHHHHHhcC
1369 Confidence 1236899999999889999998877 56788999999999999999887 4887 789999999999999999988 66
1370
1371
1372 Q sp|Q9BYF1|ACE2 414 TPKHLKSIGL-LSPDFQE--------DNETEINF----LLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM 480 (805)
1373 Q Consensus 414 tpkhlksigl-lspdfqe--------dneteinf----llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwem 480 (805)
1374 .+.+++.+.. ++..|.+ +-...+|. +.++++..+..+++......|+|-+|.|+++.+++.+.||++
1375 T Consensus 308 ~~~~l~~~~~~~~~~~~~~l~~~~~~~l~~~l~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~~~~~~~~l~~~w~~~ 387 (501)
1376 T 3HQ2_B 308 NKHFWTPYYKKIQEASPVQFKDISLDDFVRAINESKPSFIRVEADELTYPLHIIIRYEIEKAIFSNEVSVEDLPSLWNQK 387 (501)
1377 T ss_dssp SGGGHHHHHHHHHHHSHHHHTTCCHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHTTTCCCGGGHHHHHHHH
1378 T ss_pred CHHHHHHHHHHHHHHCCccccCCCHHHHHHHHHhcCCCcchhHhHhhhHhHHHHHHHHHHHHHHcCCCCHhhHHHHHHHH
1379 Confidence 6666654422 2211111 11222332 333444445556666666799999999999889999999999
1380
1381
1382 Q sp|Q9BYF1|ACE2 481 KREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDI-SNSTEAGQKL-FN 556 (805)
1383 Q Consensus 481 kreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdi-snsteagqkl-fn 556 (805)
1384 ..+..|+..|. + ..++.+..|++.+| .+++|....++++|+.+++|+... .+|.|+. .+..++|++| -+
1385 T Consensus 388 ~~~y~g~~~~~--~--~~~~~~~~H~~~~~~~yy~~Y~~~~i~a~ql~~~~~~~~~---~~~~~~~~~~~~~~~~~l~~~ 460 (501)
1386 T 3HQ2_B 388 YQDYLGITPQT--D--AEGILQDVHWAGGDFGYFPSYALGYMYAAQLKQKMLEDLP---EFDALLERGEFHPIKQWLTEK 460 (501)
1387 T ss_dssp HHHHHSCCCCS--T--TTTGGGCSTTTTTCTTCTHHHHHHHHHHHHHHHHHHHHCT---THHHHHHTTCCHHHHHHHHHH
1388 T ss_pred HHHHhCCCCCC--C--CCcchhccccccccccCchHHHHHHHHHHHHHHHHHHhCc---cHHHHHHcCCchHHHHHHHHc
1389 Confidence 99999986553 2 26778889998764 488999999999999999998765 4899987 4566999999 49
1390
1391
1392 Q sp|Q9BYF1|ACE2 557 MLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1393 Q Consensus 557 mlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1394 +|..|.+.||.-.++.+.|. .+++++++.||+|+++|+.+
1395 T Consensus 461 ~l~~G~s~~~~e~l~~~~G~-~l~~~~~l~~~~~~~~~~~~ 500 (501)
1396 T 3HQ2_B 461 VHIHGKRKKPLDIIKDATGE-ELNVRYLIDYLSNKYSNLYL 500 (501)
1397 T ss_dssp TGGGTTSSCHHHHHHHHHSS-CCCTHHHHHHHHHHHHHTTC
1398 T ss_pred ccccccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1399 Confidence 99999999999999999998 89999999999999999864
1400
1401
1402 No 16
1403 >1K9X_B m32 carboxypeptidase; HEXXH motif, M32 family, metallopeptidase; 2.3A {Pyrococcus furiosus} SCOP: d.92.1.5
1404 Probab=100.00 E-value=1.1e-46 Score=357.76 Aligned_cols=470 Identities=16% Similarity=0.193 Sum_probs=361.6 Template_Neff=9.800
1405
1406 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 99 (805)
1407 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqa 99 (805)
1408 ..|+++.++|++++++...+.+++++++|+++||+++.+.+...++...++.++. +.+.+-.++-+|..
1409 T Consensus 4 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~wd~~t~~~~~~~~~~~~~~~~l~~~~~-----------~~~~~~~~~~~l~~ 72 (499)
1410 T 1K9X_B 4 VFQNETIKQILAKYRRIWAIGHAQSVLGWDLEVNMPKEGILERSVAQGELSVLSH-----------ELLLHPEFVNLVEK 72 (499)
1411 T ss_dssp CCCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHHHH-----------HHHTCHHHHHHHHH
1412 T ss_pred hhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCChhHHHHHHHHHHHHHHHHH-----------HHhhCHHHHHHHHH
1413 Confidence 3578899999999999999999999999999999999998887776666655544 35567778888888
1414
1415
1416 Q sp|Q9BYF1|ACE2 100 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLR 177 (805)
1417 Q Consensus 100 lqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlr 177 (805)
1418 +++. +.+++. ...+++.|..+|..+. .+.|.+.++++++. ++|.++|+.||.. + +.++
1419 T Consensus 73 ~~~~--~~l~~~----~~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~--~~~~~~w~~~~~~-~~~~~~~ 132 (499)
1420 T 1K9X_B 73 AKGL--ENLNEY----ERGIVRVLDRSIRIAR-----------AFPPEFIREVSETT--SLATKAWEEAKAK-DDFSKFE 132 (499)
1421 T ss_dssp HHHC--SSCCHH----HHHHHHHHHHHHHHHT-----------SSCHHHHHHHHHHH--HHHHHHHHHHHHT-TCGGGTH
1422 T ss_pred Hhcc--CCCCHH----HHHHHHHHHHHHHHHh-----------cCCHHHHHHHHHHH--HHHHHHHHHHHHc-CChHHhH
1423 Confidence 7765 344432 2346788888888764 46688999998875 6899999999984 7 8999
1424
1425
1426 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1427 Q Consensus 178 plyeeyvvlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1428 |+++++|-++++.|+.+.|++ +.|||...|+- +...++++..|++|+|+|..||++++.+. .
1429 T Consensus 133 ~~l~~lv~l~~~~A~~~G~~~s~~d~~~~~~~~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~--~----- 195 (499)
1430 T 1K9X_B 133 PWLDKIISLAKRAAEYLGYEEEPYDALLDLYEE----------GLRTRDVEKMFEVLEKKLKPLLDKILEEG--K----- 195 (499)
1431 T ss_dssp HHHHHHHHHHHHHHHHHCCSSCHHHHHHHHHST----------TCCHHHHHHHHHHCCCCCHHHHHHHHHHC--S-----
1432 T ss_pred HHHHHHHHHHHHHHHHcCCCCCHHHHHHHHhcC----------CCCHHHHHHHHHHHHHHHHHHHHHHHhcC--C-----
1433 Confidence 999999999999999999995 99999776653 34568999999999999999999999852 0
1434
1435
1436 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1437 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1438 .|+ +.|+. .+-++..++++.+++||.++|++.++.|..
1439 T Consensus 196 -----~~~-----------------~~p~~------------~~~~~~~~~~~~~~~~~~~lG~~~~~~~r~-------- 233 (499)
1440 T 1K9X_B 196 -----VPR-----------------EHPLE------------KEKYEREWMERVNLWILQKFGFPLGTRARL-------- 233 (499)
1441 T ss_dssp -----SCS-----------------CCGGG------------TCBCCHHHHHHHHHHHHHHHTCCBTTTEEE--------
1442 T ss_pred -----CCC-----------------CCccc------------cccCCHHHHHHHHHHHHHHhCCCcccCCcc--------
1443 Confidence 121 11221 122233457788999999999998853321
1444
1445
1446 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAA-QPFL-LRNGANEGFHEAVGEIMSLSA 412 (805)
1447 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaa-qpfl-lrnganegfheavgeimslsa 412 (805)
1448 .-.|||.+|+++.+|+||.+|...+ ++|+.+.||||||+.|.+.+.. +|.+ ++.+++.+|||+++..|....
1449 T Consensus 234 ----dk~~~~~~~~~~~~d~rI~~~~~~~~~~~~~~tl~HE~GHa~y~~~~~~~~~~~~~~~~~~~~~~E~~S~~~E~~~ 309 (499)
1450 T 1K9X_B 234 ----DVSAHPFTTEFGIRDVRITTRYEGYDFRRTILSTVHEFGHALYELQQDERFMFTPIAGGVSLGIHESQSRFWENII 309 (499)
1451 T ss_dssp ----EECSSCCEEEEETTEEEEEECCCSBCTHHHHHHHHHHHHHHHHHHTSCGGGTTSTTSSCSCHHHHHHHHHCCCCCC
1452 T ss_pred ----ccCCCCeeecCCcccEEEEeeecCccHHHHHHHHHHHHHHHHHHccCCccccCCcccccccchhHHHHHHHHHHHh
1453 Confidence 1589999999998999999999886 7899999999999999998875 5543 578899999999999998655
1454
1455
1456 Q sp|Q9BYF1|ACE2 413 ATP----KHLKSIGLLSPDFQ-------EDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKW 477 (805)
1457 Q Consensus 413 atp----khlksigllspdfq-------ednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkw 477 (805)
1458 ..+ +++.. .++..+. ++-...++ .+++.++..+..++...+.-.|+|.+|.|+++.+++.+.|
1459 T Consensus 310 ~~~~~~~~~l~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~~~~~~~~l~~~w 387 (499)
1460 T 1K9X_B 310 GRSKEFVELIYP--VLKENLPFMSNYTPEDVYLYFNIVRPDFIRTEADVVTYNFHILLRFKLERLMVSEEIKAKDLPEMW 387 (499)
1461 T ss_dssp TTSHHHHHHHHH--HHHHHCGGGGGCCHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHHSCCCGGGHHHHH
1462 T ss_pred cCCHHHHHHHHH--HHHHHCCCCCCCCHHHHHHHHhccCccccccccchhhHhHHHHHHHHHHHHHhcCCCCHHHhhHHH
1463 Confidence 433 33321 1222121 11112222 1222222233333334445678999999999999999999
1464
1465
1466 Q sp|Q9BYF1|ACE2 478 WEMKREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDI-SNSTEAGQKL 554 (805)
1467 Q Consensus 478 wemkreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdi-snsteagqkl 554 (805)
1468 |++..+..|+..|. +. .+.....|++.++ .|++|....++++|+.+++|+.. |+++.|.. ....++|++|
1469 T Consensus 388 ~~~~~~y~G~~~~~--~~--~~~~~~~H~~~~~~~yy~~Y~~~~i~a~ql~~~~~~~~---~~~~~~~~~~~~~~~g~~l 460 (499)
1470 T 1K9X_B 388 NDEMERLLGIRPRK--YS--EGILQDIHWAHGSIGYFPTYTIGTLLSAQLYYHIKKDI---PDFEEKVAKAEFDPIKAWL 460 (499)
1471 T ss_dssp HHHHHHHHSCCCSS--GG--GTTTSCSHHHHTCCSCTHHHHHHHHHHHHHHHHHTTTC---TTHHHHHHHTCCHHHHHHH
1472 T ss_pred HHHHHHHhCCCCCC--CC--CcchhhccccccccccchHHHHHHHHHHHHHHHHHHHC---CcHHHHHHcCCcHHHHHHH
1473 Confidence 99999999987543 22 4667888988766 67899999999999999999875 36777744 3447899999
1474
1475
1476 Q sp|Q9BYF1|ACE2 555 F-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFT 593 (805)
1477 Q Consensus 555 f-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplft 593 (805)
1478 . ++++.|.+.||.-.++.+.|. .++..|+++||+|++.
1479 T Consensus 461 ~~~~l~~G~~~~~~e~l~~~~G~-~l~~~~ll~~~~~~~~ 499 (499)
1480 T 1K9X_B 461 REKIHRWGSIYPPKELLKKAIGE-DMDAEYFVRWVKEKYL 499 (499)
1481 T ss_dssp HHHTGGGTTSSCHHHHHHHHHSS-CCCTHHHHHHHHHHHC
1482 T ss_pred HHcchhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHhC
1483 Confidence 5 999999999999999999999 7999999999999873
1484
1485
1486 No 17
1487 >1KA2_A M32 carboxypeptidase; HEXXH motif, M32 family, metallopeptidase; 2.2A {Pyrococcus furiosus} SCOP: d.92.1.5
1488 Probab=100.00 E-value=1.1e-46 Score=357.76 Aligned_cols=470 Identities=16% Similarity=0.193 Sum_probs=361.6 Template_Neff=9.800
1489
1490 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 99 (805)
1491 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqa 99 (805)
1492 ..|+++.++|++++++...+.+++++++|+++||+++.+.+...++...++.++. +.+.+-.++-+|..
1493 T Consensus 4 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~wd~~t~~~~~~~~~~~~~~~~l~~~~~-----------~~~~~~~~~~~l~~ 72 (499)
1494 T 1KA2_A 4 VFQNETIKQILAKYRRIWAIGHAQSVLGWDLEVNMPKEGILERSVAQGELSVLSH-----------ELLLHPEFVNLVEK 72 (499)
1495 T ss_dssp CSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHHHH-----------HHHTCHHHHHHHHH
1496 T ss_pred hhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCChhHHHHHHHHHHHHHHHHH-----------HHhhCHHHHHHHHH
1497 Confidence 3578899999999999999999999999999999999998887776666655544 35567778888888
1498
1499
1500 Q sp|Q9BYF1|ACE2 100 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLR 177 (805)
1501 Q Consensus 100 lqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlr 177 (805)
1502 +++. +.+++. ...+++.|..+|..+. .+.|.+.++++++. ++|.++|+.||.. + +.++
1503 T Consensus 73 ~~~~--~~l~~~----~~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~--~~~~~~w~~~~~~-~~~~~~~ 132 (499)
1504 T 1KA2_A 73 AKGL--ENLNEY----ERGIVRVLDRSIRIAR-----------AFPPEFIREVSETT--SLATKAWEEAKAK-DDFSKFE 132 (499)
1505 T ss_dssp HHTC--SSCCHH----HHHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHH--HHHHHHHHHHHHT-TCGGGTH
1506 T ss_pred Hhcc--CCCCHH----HHHHHHHHHHHHHHHh-----------cCCHHHHHHHHHHH--HHHHHHHHHHHHc-CChHHhH
1507 Confidence 7765 344432 2346788888888764 46688999998875 6899999999984 7 8999
1508
1509
1510 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1511 Q Consensus 178 plyeeyvvlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1512 |+++++|-++++.|+.+.|++ +.|||...|+- +...++++..|++|+|+|..||++++.+. .
1513 T Consensus 133 ~~l~~lv~l~~~~A~~~G~~~s~~d~~~~~~~~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~--~----- 195 (499)
1514 T 1KA2_A 133 PWLDKIISLAKRAAEYLGYEEEPYDALLDLYEE----------GLRTRDVEKMFEVLEKKLKPLLDKILEEG--K----- 195 (499)
1515 T ss_dssp HHHHHHHHHHHHHHHHHCCSSCHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHHTT--C-----
1516 T ss_pred HHHHHHHHHHHHHHHHcCCCCCHHHHHHHHhcC----------CCCHHHHHHHHHHHHHHHHHHHHHHHhcC--C-----
1517 Confidence 999999999999999999995 99999776653 34568999999999999999999999852 0
1518
1519
1520 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1521 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1522 .|+ +.|+. .+-++..++++.+++||.++|++.++.|..
1523 T Consensus 196 -----~~~-----------------~~p~~------------~~~~~~~~~~~~~~~~~~~lG~~~~~~~r~-------- 233 (499)
1524 T 1KA2_A 196 -----VPR-----------------EHPLE------------KEKYEREWMERVNLWILQKFGFPLGTRARL-------- 233 (499)
1525 T ss_dssp -----SCS-----------------CCGGG------------TCBCCHHHHHHHHHHHHHHHTCCBTTTEEE--------
1526 T ss_pred -----CCC-----------------CCccc------------cccCCHHHHHHHHHHHHHHhCCCcccCCcc--------
1527 Confidence 121 11221 122233457788999999999998853321
1528
1529
1530 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAA-QPFL-LRNGANEGFHEAVGEIMSLSA 412 (805)
1531 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaa-qpfl-lrnganegfheavgeimslsa 412 (805)
1532 .-.|||.+|+++.+|+||.+|...+ ++|+.+.||||||+.|.+.+.. +|.+ ++.+++.+|||+++..|....
1533 T Consensus 234 ----dk~~~~~~~~~~~~d~rI~~~~~~~~~~~~~~tl~HE~GHa~y~~~~~~~~~~~~~~~~~~~~~~E~~S~~~E~~~ 309 (499)
1534 T 1KA2_A 234 ----DVSAHPFTTEFGIRDVRITTRYEGYDFRRTILSTVHEFGHALYELQQDERFMFTPIAGGVSLGIHESQSRFWENII 309 (499)
1535 T ss_dssp ----EECSSCCEEEEETTEEEEEECCCSBCTHHHHHHHHHHHHHHHHHHTCCGGGTTSTTSSCCCHHHHHHHHHCCCCCC
1536 T ss_pred ----ccCCCCeeecCCcccEEEEeeecCccHHHHHHHHHHHHHHHHHHccCCccccCCcccccccchhHHHHHHHHHHHh
1537 Confidence 1589999999998999999999886 7899999999999999998875 5543 578899999999999998655
1538
1539
1540 Q sp|Q9BYF1|ACE2 413 ATP----KHLKSIGLLSPDFQ-------EDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKW 477 (805)
1541 Q Consensus 413 atp----khlksigllspdfq-------ednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkw 477 (805)
1542 ..+ +++.. .++..+. ++-...++ .+++.++..+..++...+.-.|+|.+|.|+++.+++.+.|
1543 T Consensus 310 ~~~~~~~~~l~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~~~~~~~~l~~~w 387 (499)
1544 T 1KA2_A 310 GRSKEFVELIYP--VLKENLPFMSNYTPEDVYLYFNIVRPDFIRTEADVVTYNFHILLRFKLERLMVSEEIKAKDLPEMW 387 (499)
1545 T ss_dssp TTSHHHHHHHHH--HHHHHCGGGGGCCHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHHSCCCGGGHHHHH
1546 T ss_pred cCCHHHHHHHHH--HHHHHCCCCCCCCHHHHHHHHhccCccccccccchhhHhHHHHHHHHHHHHHhcCCCCHHHhhHHH
1547 Confidence 433 33321 1222121 11112222 1222222233333334445678999999999999999999
1548
1549
1550 Q sp|Q9BYF1|ACE2 478 WEMKREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDI-SNSTEAGQKL 554 (805)
1551 Q Consensus 478 wemkreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdi-snsteagqkl 554 (805)
1552 |++..+..|+..|. +. .+.....|++.++ .|++|....++++|+.+++|+.. |+++.|.. ....++|++|
1553 T Consensus 388 ~~~~~~y~G~~~~~--~~--~~~~~~~H~~~~~~~yy~~Y~~~~i~a~ql~~~~~~~~---~~~~~~~~~~~~~~~g~~l 460 (499)
1554 T 1KA2_A 388 NDEMERLLGIRPRK--YS--EGILQDIHWAHGSIGYFPTYTIGTLLSAQLYYHIKKDI---PDFEEKVAKAEFDPIKAWL 460 (499)
1555 T ss_dssp HHHHHHHHSCCCSS--GG--GTTTSCSHHHHTCTTCTHHHHHHHHHHHHHHHHHHHHC---TTHHHHHHHTCCHHHHHHH
1556 T ss_pred HHHHHHHhCCCCCC--CC--CcchhhccccccccccchHHHHHHHHHHHHHHHHHHHC---CcHHHHHHcCCcHHHHHHH
1557 Confidence 99999999987543 22 4667888988766 67899999999999999999875 36777744 3447899999
1558
1559
1560 Q sp|Q9BYF1|ACE2 555 F-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFT 593 (805)
1561 Q Consensus 555 f-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplft 593 (805)
1562 . ++++.|.+.||.-.++.+.|. .++..|+++||+|++.
1563 T Consensus 461 ~~~~l~~G~~~~~~e~l~~~~G~-~l~~~~ll~~~~~~~~ 499 (499)
1564 T 1KA2_A 461 REKIHRWGSIYPPKELLKKAIGE-DMDAEYFVRWVKEKYL 499 (499)
1565 T ss_dssp HHHTGGGTTSSCHHHHHHHHHSS-CCCTHHHHHHHHHHHC
1566 T ss_pred HHcchhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHhC
1567 Confidence 5 999999999999999999999 7999999999999873
1568
1569
1570 No 18
1571 >5E3X_A Thermostable carboxypeptidase 1; Carboxypeptidase, Fervidobacterium, FisCP, HYDROLASE; 2.197A {Fervidobacterium islandicum}
1572 Probab=100.00 E-value=2.4e-46 Score=356.74 Aligned_cols=456 Identities=17% Similarity=0.229 Sum_probs=345.9 Template_Neff=9.600
1573
1574 Q sp|Q9BYF1|ACE2 27 TFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSS 106 (805)
1575 Q Consensus 27 tfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngss 106 (805)
1576 .||+.++.+++.+.++.++++|+|.||+++++.+.+..+...++.+ ..+.+++-+++-||+.++..
1577 T Consensus 2 ~~l~~~~~~~~~~~~~~~~~~Wd~~t~~~~~~~~~r~~~~~~l~~~-----------~~~~~~~~~~~~~l~~~~~~--- 67 (489)
1578 T 5E3X_A 2 EELKSYYKRVAKYYSAAALLYWDMQTYMPKDAGPYRAEVLSEIGTY-----------AFKQITDDALGKLLETAQPQ--- 67 (489)
1579 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHH-----------HHHHHTSHHHHHHHHHCCCC---
1580 T ss_pred hHHHHHHHHHHHHHHHHHHHHHHHHhcCCCCchHHHHHHHHHHHHH-----------HHHHhcCHHHHHHHHHhCCC---
1581 Confidence 4889999999999999999999999999999998766665555543 33457788899999888752
1582
1583
1584 Q sp|Q9BYF1|ACE2 107 VLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLRPLYEEYV 184 (805)
1585 Q Consensus 107 vlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlrplyeeyv 184 (805)
1586 +.+...++..|..+|++++++ .|.+-++++++.+..+ ++|..||.. + +.++|.|+++|
1587 T Consensus 68 ------~~~~~~~~~~~~~~~~~~~~~-----------~~~l~~~~~~~~~~~~--~~W~~~r~~-~~~~~~~~~~~~~v 127 (489)
1588 T 5E3X_A 68 ------SEIDEKLVYVGKKEYYKYKKV-----------PPELFQEIMITSTMLE--QKWEIAKPR-GDFEEVRPLLEKIV 127 (489)
1589 T ss_dssp ------SHHHHHHHHHHHHHHHHHHTS-----------CHHHHHHHHHHHHHHH--HHHHHHGGG-TCSTTTHHHHHHHH
1590 T ss_pred ------CHHHHHHHHHHHHHHHhccCC-----------CHHHHHHHHHhhhHHH--HHHHHHHhc-CCHHHHHHHHHHHH
1591 Confidence 234667788999999998763 4667788888888776 999999996 8 89999999999
1592
1593
1594 Q sp|Q9BYF1|ACE2 185 VLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLP 263 (805)
1595 Q Consensus 185 vlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispigclp 263 (805)
1596 -+.|++|+.+.|++ .+++|...|+-. + ..++++..|++| +.+||..|.+.|+.. |
1597 T Consensus 128 ~l~~~~A~~~g~~~~~y~~~~~~y~~~----~------~~~~l~~~~~~l-------~~~v~~~l~~~~~~~-------~ 183 (489)
1598 T 5E3X_A 128 DLSRKYADILGYEGEPYNALLDLYEPG----M------KAEEVDQIFSKV-------RDFIVEVLEKIERLP-------K 183 (489)
1599 T ss_dssp HHHHHHHHTTCCSSCHHHHHHHHHSTT----C------CHHHHHHHHHHH-------HHHHHHHHHHHHHSC-------C
1600 T ss_pred HHHHHHHHHhCCCCChHHHHHHHhCCC----C------CHHHHHHHHHHH-------HHHHHHHHHHHhcCC-------C
1601 Confidence 99999999999987 568887766542 1 124455555554 556888887777431 3
1602
1603
1604 Q sp|Q9BYF1|ACE2 264 AHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAV 343 (805)
1605 Q Consensus 264 ahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkav 343 (805)
1606 +| +.++.|+.. + .++.+. +.++.+.|... ++|... ..
1607 T Consensus 184 ~~-------------~~~~~~~~~----~-----------~~~~~~--~~~~~~~g~d~------------~~~~~~-~~ 220 (489)
1608 T 5E3X_A 184 SE-------------DPFNREIGV----D-----------KQKEFS--NWLLHYLKYDF------------TKGRLD-VS 220 (489)
1609 T ss_dssp CC-------------CTTCSCCCH----H-----------HHHHHH--HHHHHHTTCCT------------TSCCEE-EC
1610 T ss_pred CC-------------CcccCCCCH----H-----------HHHHHH--HHHHHHcCCCC------------CCCCee-cc
1611 Confidence 32 223333321 1 122222 45667777665 122221 38
1612
1613
1614 Q sp|Q9BYF1|ACE2 344 CHPTAWDLGKGDFRILMCT--KVTMDDFLTAHHEMGHIQYDMAYAAQ--PFLLRNGANEGFHEAVGEIMSLSAAT----- 414 (805)
1615 Q Consensus 344 chptawdlgkgdfrilmct--kvtmddfltahhemghiqydmayaaq--pfllrnganegfheavgeimslsaat----- 414 (805)
1616 |||..++++.+|+||.+|. +++++|+.+.|||+||++|.+.+..+ ...++.+++.+|||+++..|.+....
1617 T Consensus 221 ~~~~~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~~~~l~~~ 300 (489)
1618 T 5E3X_A 221 AHPFTNPIGLNDVRITTRYIVNDIRNSIYSTIHEFGHALYALSIPTEFYGLPIGSSASYGFDESQSRFWENVVGRSLAFW 300 (489)
1619 T ss_dssp SSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHHHSCGGGTTSGGGSCSCHHHHHHHHHCCCCCCTTSHHHH
1620 T ss_pred CCCccCCCCCCceEEeeeccccchhHHHHHHHHHHHHHHHHcCCChHHcCCCCccccCcccchhHHHHHHHHhhcCHHHH
1621 Confidence 9999999988999999999 99999999999999999999988752 22236789999999999999887776
1622
1623
1624 Q sp|Q9BYF1|ACE2 415 ----PKHLKSIGLLSPDFQEDNETEINFLLKQALT-IVGT-------LPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKR 482 (805)
1625 Q Consensus 415 ----pkhlksigllspdfqedneteinfllkqalt-ivgt-------lpftymlekwrwmvfkgeipkdqwmkkwwemkr 482 (805)
1626 |+|++.+|++. +.. ..++...+.++.. ...+ ++...+...|+|.++.|+++.+++-+.||+...
1627 T Consensus 301 ~~~~~~~~~~l~~~~-~~~---~~~~~~~l~~~~~~~~~~~~d~l~~~~~~~~~~~~e~~~~~g~~~~~~l~~~w~~~~~ 376 (489)
1628 T 5E3X_A 301 KGIYSKFIEIVPEMR-GYS---VEELWRAVNRVQRSFIRTEADEVTYNLHIIIRFEIERELINGELSVKDVPDKWNELYK 376 (489)
1629 T ss_dssp HHHHHHHHHHCGGGT-TSC---HHHHHHHTSCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHTTSSCGGGHHHHHHHHHH
1630 T ss_pred HHHHHHHHHHchhhc-CCC---HHHHHHHHHHHccccchhHhHHHHHHHHHHHHHHHHHHHHhCCCCHhhhhHHHHHHHH
1631 Confidence 77878887651 221 1122222222211 1121 244567799999999999999999999999999
1632
1633
1634 Q sp|Q9BYF1|ACE2 483 EIVGVVEPVPHDETYCDPASLFHVSN-DY-SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDIS-NS-TEAGQKLF-NM 557 (805)
1635 Q Consensus 483 eivgvvepvphdetycdpaslfhvsn-dy-sfiryytrtlyqfqfqealcqaakhegplhkcdis-ns-teagqklf-nm 557 (805)
1636 +..|+..|. + ..++....|+.. .| .+++|....++++|+.+++|+.. +++.| +. ++ .++|+.|- ++
1637 T Consensus 377 ~y~g~~~~~--~--~~~~~~~~h~~~~~~~y~~~Y~~~~i~a~ql~~~~~~~~----~~~~~-~~~~~~~~~g~~l~~~~ 447 (489)
1638 T 5E3X_A 377 KYLGLDVPN--N--TLGCMQDPHWFGGNFGYFPTYALGNLYAAQIFEKLKEEI----NFEEV-VSAGNFEIIKNFLKEKI 447 (489)
1639 T ss_dssp HHHCCCCCS--T--TTTTTSCSGGGGTCCSCTHHHHHHHHHHHHHHHHHHHHS----CHHHH-HHHTCTHHHHHHHHHHT
1640 T ss_pred HHhCCCCCC--C--CCCCCCCCcccccccchhHHHHHHHHHHHHHHHHHHHcC----CHHHH-HhcCCHHHHHHHHHHch
1641 Confidence 999975443 2 235667788875 67 89999999999999999999865 69999 54 55 57899998 59
1642
1643
1644 Q sp|Q9BYF1|ACE2 558 LRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1645 Q Consensus 558 lrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1646 +..|.+.||.-.++++.|. .+++++++.||+|++.|+..
1647 T Consensus 448 l~~G~~~~~~e~l~~~~G~-~ls~~~~l~~~~~~~~~~~~ 486 (489)
1648 T 5E3X_A 448 HSKGKMYEPSDLIKIVTGK-PLSYESFVRYIKDKYSKVYE 486 (489)
1649 T ss_dssp GGGTTSSCHHHHHHHHHSS-CCCSHHHHHHHHHHHHHHHT
1650 T ss_pred hhcCcCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1651 Confidence 9999999999999999998 89999999999999999974
1652
1653
1654 No 19
1655 >3HOA_A Thermostable carboxypeptidase 1 (E.C.3.4.17.19); proline-rich loop, Carboxypeptidase, Hydrolase; 2.1A {Thermus thermophilus HB27}
1656 Probab=100.00 E-value=1.1e-45 Score=356.95 Aligned_cols=468 Identities=19% Similarity=0.228 Sum_probs=373.5 Template_Neff=9.300
1657
1658 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
1659 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
1660 ++++..||++++.+...+-+..++++|++.|++++.+.+..... .++|+.. -.+.+.+-.++-+|..++
1661 T Consensus 3 ~~~~~~~l~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~r~~~----------~~~l~~~-~~~~~~~~~~~~~l~~~~ 71 (509)
1662 T 3HOA_A 3 PEAAYQNLLEFQRETAYLASLGALAAWDQRTMIPKKGHEHRARQ----------MAALARL-LHQRMTDPRIGEWLEKVE 71 (509)
1663 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHH----------HHHHHHH-HHHHHTCHHHHHHHHHHT
1664 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCCCHHhHHHHHHH----------HHHHHHH-HHHhhcCHHHHHHHHHHc
1665 Confidence 56788999999999999999999999999999998876443322 2233332 234566777888888887
1666
1667
1668 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEV-GKQLRPLY 180 (805)
1669 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsev-gkqlrply 180 (805)
1670 .. ...+.+ ...+..++..|..+|...+ .++|.+.++|+++.++.+ ++|..||.+. +..++|.+
1671 T Consensus 72 ~~-~~~~~~--~~~~~~~~~~~~~~~~~~~-----------~~~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~~~l 135 (509)
1672 T 3HOA_A 72 GS-PLVQDP--LSDAAVNVREWRQAYERAR-----------AIPERLAVELAQAESEAE--SFWEEARPRDDWRGFLPYL 135 (509)
1673 T ss_dssp TS-GGGSST--TSHHHHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHTTTTCHHHHHHHH
1674 T ss_pred CC-CCCCCC--CHHHHHHHHHHHHHHHHHc-----------CCCHHHHHHHHHcccHHH--HHHHHhhhhCChhhhHHHH
1675 Confidence 65 333332 4556678899999998766 678899999999999999 8999999998 89999999
1676
1677
1678 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYE----------DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1679 Q Consensus 181 eeyvvlknemaranhye----------dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1680 +++|-++|+.|+.+.|. ++.|||...|+- |...++++..|++|+|+|..||+|||.+.
1681 T Consensus 136 ~~~v~l~~~~A~~~g~~~~~~~~~~~~~~~d~~l~~ye~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~-- 203 (509)
1682 T 3HOA_A 136 KRVYALTKEKAEVLFALPPAPGDPPYGELYDALLDGYEP----------GMRARELLPLFAELKEGLKGLLDRILGSG-- 203 (509)
1683 T ss_dssp HHHHHHHHHHHHHHHTSCCCTTSCCCCSHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHTCS--
1684 T ss_pred HHHHHHHHHHHHHhhcCCCCCCCCCCCCHHHHHHHccCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHccC--
1685 Confidence 99999999999999997 999999988872 22358899999999999999999999964
1686
1687
1688 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWEN 330 (805)
1689 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwen 330 (805)
1690 |. | |+|++ .+.+...+.++-++++|.+.|+.. ++
1691 T Consensus 204 -~~----~----~~~~~-------------------------------~~~~~~~~~~~~~~~~~~~lG~~~------~~ 237 (509)
1692 T 3HOA_A 204 -KR----P----DTSIL-------------------------------HRPYPVEAQRRFALELLSACGYDL------EA 237 (509)
1693 T ss_dssp -CC----C----CGGGG-------------------------------GSCCCHHHHHHHHHHHHHHHTCCG------GG
1694 T ss_pred -CC----C----Cchhh-------------------------------cCCCCHHHHHHHHHHHHHHCCCCh------hh
1695 Confidence 21 1 44421 122233456788899999999886 12
1696
1697
1698 Q sp|Q9BYF1|ACE2 331 SMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAYAA----QPFLLRNGANEGFHEAV 404 (805)
1699 Q Consensus 331 smltdpgnvqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmayaa----qpfllrnganegfheav 404 (805)
1700 +. +. ..|||.+|+++.+|+||++|.. ..++++.+.|||+||..|.+.+.. +| ++.+++.+|||++
1701 T Consensus 238 ~~------~d-k~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~--~~~~~~~~~~E~~ 308 (509)
1702 T 3HOA_A 238 GR------LD-PTAHPFEIAIGPGDVRITTRYYEDFFNAGIFGTLHEMGHALYEQGLPKEHWGTP--RGDAVSLGVHESQ 308 (509)
1703 T ss_dssp EE------EE-ECSSCCEEEEETTEEEEEECCBTTBHHHHHHHHHHHHHHHHHHHHSCGGGTTSG--GGSCCCHHHHHHH
1704 T ss_pred CC------CC-CCCCcceeccCCCceEEEEeeccchhhHHHHHHHHHHHHHHHHhCCCHHHCCCC--CcCCCCchhHHHH
1705 Confidence 21 11 5799999999988999999998 899999999999999999998843 44 5678999999999
1706
1707
1708 Q sp|Q9BYF1|ACE2 405 GEIMS----LSAATPKHLKS-----IGLLSPDFQEDNETEINF----LLKQALTIVGTLPFTYMLEKWRW--MVFKGEIP 469 (805)
1709 Q Consensus 405 geims----lsaatpkhlks-----igllspdfqedneteinf----llkqaltivgtlpftymlekwrw--mvfkgeip 469 (805)
1710 +..|. .+..+++++.. +|++++...++-...+|. ++++++..+. .|+.+++ +|+| .++.|+++
1711 T Consensus 309 s~~~E~~~~~~~~~~~~l~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~r~~~~~~~-~~~~~~~-~~~~E~~l~~~~~~ 386 (509)
1712 T 3HOA_A 309 SRTWENLVGRSLGFWERFFPRAREVFASLGDVSLEDFHFAVNAVEPSLIRVEADEVT-YNLHILV-RLELELALFRGELS 386 (509)
1713 T ss_dssp HHCCCCCCTTSHHHHHHHHHHHHHHCGGGTTCCHHHHHHHTTCCCCCSCGGGCCTTT-HHHHHHH-HHHHHHHHHTTSCC
1714 T ss_pred HHHHHHHhcCCHHHHHHHHHHHHHHhhccCCCCHHHHHHHHHccChhHHHHHhHHhH-hhHHHHH-HHHHHHHHHcCCCC
1715 Confidence 99998 67778877765 676544324444566666 7888887765 8998888 9999 89999999
1716
1717
1718 Q sp|Q9BYF1|ACE2 470 KDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSND--YSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDIS-- 545 (805)
1719 Q Consensus 470 kdqwmkkwwemkreivgvvepvphdetycdpaslfhvsnd--ysfiryytrtlyqfqfqealcqaakhegplhkcdis-- 545 (805)
1720 .+++-+.||+..++..|+..|. +...| ....|.+.. +.|.+|....++++|+.+++|+.. |+++.| +.
1721 T Consensus 387 ~~~l~~~w~~~~~~y~G~~~~~--~~~~~--~~~~h~~~~~~~Y~~~Y~~g~i~a~ql~~~~~~~~---~~~~~~-~~~~ 458 (509)
1722 T 3HOA_A 387 PEDLPEAWAEKYRDHLGVAPKD--YKDGV--MQDVHWAGGLFGYFPTYTLGNLYAAQFFQKAEAEL---GPLEPR-FARG 458 (509)
1723 T ss_dssp GGGHHHHHHHHHHHHHSCCCSS--STTTT--TSCSTTTTTCCSCTHHHHHHHHHHHHHHHHHHHHH---CCHHHH-HHHT
1724 T ss_pred HhHHhHHHHHHHHHHhCCCCCC--CCCCc--cccCcccCCccchhHHHHHHHHHHHHHHHHHHHHH---CChhHH-hhcC
1725 Confidence 9999999999999999987553 33333 444566543 345688899999999999999876 489999 54
1726
1727
1728 Q sp|Q9BYF1|ACE2 546 NSTEAGQKLF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTW 594 (805)
1729 Q Consensus 546 nsteagqklf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftw 594 (805)
1730 +..++|..|- ++++.|.+.+|.-.++.+.|. .++..+++.||++.+.-
1731 T Consensus 459 ~~~~~g~~l~~~il~~G~s~~~~ell~~~~G~-~l~~~~~l~~~~~~~~~ 507 (509)
1732 T 3HOA_A 459 EFQPFLDWTRARIHAEGSRFRPRVLVERVTGE-APSARPFLAYLEKKYAA 507 (509)
1733 T ss_dssp CCHHHHHHHHHHTGGGTTSSCHHHHHHHHHSS-CCCSHHHHHHHHHHHHH
1734 T ss_pred CcHHHHHHHHHhHHhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHH
1735 Confidence 4579999997 899999999999999999998 89999999999987753
1736
1737
1738 No 20
1739 >3DWC_B Metallocarboxypeptidase (E.C.3.4.17.19); metallocarboxypeptidase, cowrin family of metallocarboxypeptidases; HET: GOL, SO4; 2.1A {Trypanosoma cruzi}
1740 Probab=100.00 E-value=2e-44 Score=343.88 Aligned_cols=459 Identities=16% Similarity=0.165 Sum_probs=360.6 Template_Neff=9.700
1741
1742 Q sp|Q9BYF1|ACE2 23 EQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE-I------QNLTVKL 95 (805)
1743 Q Consensus 23 eqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqe-i------qnltvkl 95 (805)
1744 ..|..||..++.+.+.+-++.++++|++.||+++.+.+.+..+..+++.++.+..+-.+++.+-+ + .+-..+.
1745 T Consensus 3 ~~~~~~l~~~~~~~~~l~~~~~~~~Wd~~t~~~~~~~~~~~~~~~~ls~~~~~~~~~~~~~~~~~~~~~~~~~ld~~~~r 82 (505)
1746 T 3DWC_B 3 MKPYKELERVFTKLYRYGHMLLLADWDSHTMMPCKGSDARGAAMAELQLHMHDTITAPKIRALIEEAEKSVGDLEKLQRA 82 (505)
1747 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHHHHHHHTSHHHHHHHHHHHHTGGGSCHHHHH
1748 T ss_pred chHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCCccHHHHHHHHHHHHHHHHhhhhCHHHHHHHHHHHhhcCCCCHHHHH
1749 Confidence 35778999999999999999999999999999999999999999999999999777555544211 1 1345677
1750
1751
1752 Q sp|Q9BYF1|ACE2 96 QLQALQQN--GSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG 173 (805)
1753 Q Consensus 96 qlqalqqn--gssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg 173 (805)
1754 ||+.++.. ++..|+++.-++++.+.+.|+.+|++.+.||. .
1755 T Consensus 83 ~l~~l~~~~~~~~~lp~~~~~~~~~~~~~~~~~w~~~r~~~~-------------------------------------~ 125 (505)
1756 T 3DWC_B 83 NLREMRRAWELENLLPEEFVERKTVLTTKAHQVWKTCREKND-------------------------------------F 125 (505)
1757 T ss_dssp HHHHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHHHHHHHHTC-------------------------------------H
1758 T ss_pred HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHhhhcCC-------------------------------------h
1759 Confidence 78888887 88899999999999999999999999888731 1
1760
1761
1762 Q sp|Q9BYF1|ACE2 174 KQLRPLYEEYVVLKNEMARANHYE---DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1763 Q Consensus 174 kqlrplyeeyvvlknemaranhye---dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1764 +.++|.++++|-++++.|+.+.|+ +..|+|...|+ .|...++++..|++|+|+|..||++||.++..
1765 T Consensus 126 ~~~~~~~~~~v~l~~~~A~~~g~~~~~~~y~~~~~~y~----------~~~~~~~ld~l~~~i~~~~~~l~~~v~~~~~~ 195 (505)
1766 T 3DWC_B 126 AGFLPTLKELIALFREEGKLRAGNSGKHPYEALVDIYE----------PGMTLQRLDEIFGNVRSWLPELLKEVQEKQKA 195 (505)
1767 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHTTSCCCHHHHHHHHHS----------TTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1768 T ss_pred hhhHHHHHHHHHHHHHHHHHHcCCCCCChHHHHHHHhC----------CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHh
1769 Confidence 578999999999999999999986 77778866555 34455889999999999999999999998762
1770
1771
1772 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWEN 330 (805)
1773 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwen 330 (805)
1774 |+ + +.+.+..||... ..++-++++|.++|... ++
1775 T Consensus 196 -~~---------------~-------~~~~~~~p~~~~-----------------~~~~~~~~~~~~lg~~~------~~ 229 (505)
1776 T 3DWC_B 196 -LG---------------E-------TVLEPKGPFPVS-----------------KQEALCRFFMDVWKFDF------DG 229 (505)
1777 T ss_dssp -HC---------------C-------CCCCCCSCCCHH-----------------HHHHHHHHHHHHTTCCT------TS
1778 T ss_pred -hC---------------C-------CCCCCCCCCCHH-----------------HHHHHHHHHHHHcCCCc------cC
1779 Confidence 21 1 112334555221 23455677888888774 22
1780
1781
1782 Q sp|Q9BYF1|ACE2 331 SMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAY-AA----QPFLLRNGANEGFHEA 403 (805)
1783 Q Consensus 331 smltdpgnvqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmay-aa----qpfllrnganegfhea 403 (805)
1784 +.+ | ..|||.+|+++ +|+||.+|.+ .+++|+.+.|||+||++|.+.+ .. ||+. .+++-+|||+
1785 T Consensus 230 ~~~-d------~~~~~f~~~~~-~d~ri~~~~~~~~~~~~~~~l~HE~GHa~y~~~~~~~~~~~~p~~--~~~~~~~~E~ 299 (505)
1786 T 3DWC_B 230 GRL-D------VSAHPFCGNSK-EDVRITTKYTETEFVTSLLGVIHETGHAKYEQNCGPKGFETQPVC--MARSLGVHEG 299 (505)
1787 T ss_dssp EEE-E------ECSSCCEEEET-TEEEEEECCBTTBSHHHHHHHHHHHHHHHHHHTCCCTTCTTSTTS--SCSCHHHHHH
1788 T ss_pred Cce-e------ecCCCccCCCC-CceEEEecCCchHHHHHHHHHHHHHHHHHHHhcCCCccccCCchh--hhcccchhHH
1789 Confidence 222 2 38999999985 8999999999 7799999999999999999988 43 7875 6899999999
1790
1791
1792 Q sp|Q9BYF1|ACE2 404 VGE----IMSLSAATPKHLKSIGLLSPDFQEDN-------ETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEI 468 (805)
1793 Q Consensus 404 vge----imslsaatpkhlksigllspdfqedn-------etein----fllkqaltivgtlpftymlekwrwmvfkgei 468 (805)
1794 ++. ++..++.+|+||..+... .|.... ..-++ .++++++..+..++...+...|+|-+|.|++
1795 T Consensus 300 ~s~~~E~~~~~~~~~~~~l~~~~~~--~~~~~~~~~~~~l~~~l~~~~~~~~r~~~~~l~~~~~~~~~~~~e~~l~~g~~ 377 (505)
1796 T 3DWC_B 300 QSLFAEMQIGRSGAFMEFLAPRLVE--YFGDQPAFTSSNMKRVIQRVSPGLIRIDADELCYPLHVMLRYEIERDLMDGNI 377 (505)
1797 T ss_dssp HHHCCCCCCCTSHHHHHHHHHHHHH--HHCCCTTCSHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHHTSS
1798 T ss_pred HHHHHHHHhhcCHHHHHHHHHHHHH--HHCCCCCCCHHHHHHHHhccCCcccHHHchhcchHHHHHHHHHHHHHHHcCCC
1799 Confidence 984 445677899999876322 222111 11122 3344444444444445566689999999999
1800
1801
1802 Q sp|Q9BYF1|ACE2 469 PKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN 546 (805)
1803 Q Consensus 469 pkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdisn 546 (805)
1804 +.+++.+.||+..++..|+..|.. + .-++.+.+|++.++ .+++|....++++|+.+++|+...+ +|++.| +.+
1805 T Consensus 378 ~~~~l~~~w~~~~~~y~g~~~~~~-~--~~~~~~~~H~~~~~~~Y~~~Y~~~~i~a~ql~~~~~~~~~~-~~~~~~-~~~ 452 (505)
1806 T 3DWC_B 378 EAEEVPRVWNEKMKSYLGLETLGN-D--KEGCLQDVHWSGGMFGYFPTYSLGAMVAAQLMSCVRRELGE-EVVDDC-IRK 452 (505)
1807 T ss_dssp CGGGHHHHHHHHHHHHHSCCCTTC-C--TTTTTSCSTTTTTCCSCTHHHHHHHHHHHHHHHHHHHHHCH-HHHHHH-HHT
1808 T ss_pred CHHHhhHHHHHHHHHHcCCCCCCC-C--cCCccccccccccccccchHHHHHHHHHHHHHHHHHHHHCc-ccHHHH-Hhc
1809 Confidence 999999999999999999876542 2 22568889988765 5789999999999999999998764 689999 543
1810
1811
1812 Q sp|Q9BYF1|ACE2 547 STEAGQKL----FNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFT 593 (805)
1813 Q Consensus 547 steagqkl----fnmlrlgksepwtlalenvvgaknmnvrpllnyfeplft 593 (805)
1814 .++|..+ -++++.|.+.+|.-.++.+.|. +++..+++.||+|+++
1815 T Consensus 453 -~~~~~~~~~l~~~~l~~G~s~~~~e~l~~~~G~-~l~~~~~~~~~~~~~~ 501 (505)
1816 T 3DWC_B 453 -GDLGKILAKQNEKIWQHGSSLTTDELLRQATGE-TLNPEHYRRHLERRYR 501 (505)
1817 T ss_dssp -TCCHHHHHHHHHHTGGGTTSSCHHHHHHHHHSS-SCCTHHHHHHHCCCCC
1818 T ss_pred -CCHHHHHHHHHHhhhhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHh
1819 Confidence 7788876 4899999999999999999998 9999999999999885
1820
1821
1822 No 21
1823 >5WVU_C Thermostable carboxypeptidase 1 (E.C.3.4.17.19); carboxypeptidase, RIKEN Structural Genomics/Proteomics Initiative; HET: GOL; 2.6A {Thermus thermophilus HB8}
1824 Probab=100.00 E-value=8.4e-44 Score=344.00 Aligned_cols=469 Identities=20% Similarity=0.238 Sum_probs=368.7 Template_Neff=9.300
1825
1826 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
1827 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
1828 ++++..||++++.+...+-...++++|++.|++++.+.+.... ..++|+... .+.+.+-.++-+|..++
1829 T Consensus 3 ~~~~~~~L~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~r~~----------~~~~l~~~~-~~~~~~~~~~~~l~~~~ 71 (510)
1830 T 5WVU_C 3 PEAAYQNLLEFQRETAYLASLGALAAWDQRTMIPKKGHEHRAR----------QMAALARLL-HQRMTDPRIGEWLEKVE 71 (510)
1831 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCGGGHHHHHH----------HHHHHHHHH-HHHHTCHHHHHHHHHHT
1832 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCCCHhhHHHHHH----------HHHHHHHHH-HHhhcCHHHHHHHHHHc
1833 Confidence 4678899999999999999999999999999999887643322 123343332 34556677888888887
1834
1835
1836 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEV-GKQLRPLY 180 (805)
1837 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsev-gkqlrply 180 (805)
1838 .. ...+.+ ......++..|..+|...+ .++|.+.++|+++.++.+ ++|+.||... +..++|.+
1839 T Consensus 72 ~~-~~~~~~--~~~~~~~~~~~~~~~~~~~-----------~~~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~~~l 135 (510)
1840 T 5WVU_C 72 GS-PLVQDP--LSDAAVNVREWRQAYERAR-----------AIPERLAVELAQAESEAE--SFWEEARPRDDWRGFLPYL 135 (510)
1841 T ss_dssp TS-GGGSST--TSHHHHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHHHHTCHHHHHHHH
1842 T ss_pred CC-CCCCCC--CHHHHHHHHHHHHHHHHHc-----------CCCHHHHHHHHHcccHHH--HHHHHHhhhCChhhhHHHH
1843 Confidence 65 333332 4455667888988888655 678999999999999998 7999999988 89999999
1844
1845
1846 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYE----------DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1847 Q Consensus 181 eeyvvlknemaranhye----------dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1848 +++|-++|++|+.+.|. ++.|||...|+ +|...++++..|++|+|++..||+|+|.+.
1849 T Consensus 136 ~~~v~l~~~~A~~~g~~~~~~~~~~~~~~~d~~l~~y~----------~~~~~~~l~~l~~~l~~~~~~l~~~~~~~~-- 203 (510)
1850 T 5WVU_C 136 KRVYALTKEKAEVLFALPPAPGDPPYGELYDALLDGYE----------PGMRARELLPLFAELKEGLKGLLDRILGSG-- 203 (510)
1851 T ss_dssp HHHHHHHHHHHHHHHTSCCSTTSCCCCSHHHHHHHHHS----------TTCCHHHHHHHHHHHHHHHHHHHHHHHTTC--
1852 T ss_pred HHHHHHHHHHHHHhhcCCCCCCCCCCCCHHHHHHHhcC----------CCCCHHHHHHHHHHHHHHHHHHHHHHHccC--
1853 Confidence 99999999999999997 99999988776 223358899999999999999999999964
1854
1855
1856 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWEN 330 (805)
1857 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwen 330 (805)
1858 |. | |+|++ .+.++..+.++-++++|.+.|+.. ++
1859 T Consensus 204 -~~----~----~~~~~-------------------------------~~~~~~~~~~~~~~~~~~~lG~~~------~~ 237 (510)
1860 T 5WVU_C 204 -KR----P----DTSIL-------------------------------HRPYPVEAQRRFALELLSACGYDL------EA 237 (510)
1861 T ss_dssp -CC----C----CGGGG-------------------------------GSCCCHHHHHHHHHHHHHHHTCCG------GG
1862 T ss_pred -CC----C----Cchhh-------------------------------cCCCCHHHHHHHHHHHHHHCCCCc------hh
1863 Confidence 21 1 44421 122223446778889999999886 12
1864
1865
1866 Q sp|Q9BYF1|ACE2 331 SMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAYA----AQPFLLRNGANEGFHEAV 404 (805)
1867 Q Consensus 331 smltdpgnvqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmaya----aqpfllrnganegfheav 404 (805)
1868 +.+ | ..|||.+|+++.+|+||.+|.. .+++++.+.|||+||..|.+.+. -+| ++.+++.+|||+.
1869 T Consensus 238 ~~~-d------k~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~--~~~~~~~~~~E~~ 308 (510)
1870 T 5WVU_C 238 GRL-D------PTAHPFEIAIGPGDVRITTRYYEDFFNAGIFGTLHEMGHALYEQGLPKEHWGTP--RGDAVSLGVHESQ 308 (510)
1871 T ss_dssp CCE-E------ECSSCCEEEEETTEEEEEECCBTTBHHHHHHHHHHHHHHHHHHHTSCGGGTTSG--GGSCSCHHHHHHH
1872 T ss_pred CCC-C------CCCCCceeecCCCceEEEEeeecchhhHHHHHHHHHHHHHHHHcCCCHHHCCCC--CccCCCchhHHHH
1873 Confidence 211 1 5799999999989999999998 89999999999999999999874 355 4578999999999
1874
1875
1876 Q sp|Q9BYF1|ACE2 405 GEIMS----LSAATPKHLKS-----IGLLSPDFQEDNETEINF----LLKQALTIVGTLPFTYMLEKWRW--MVFKGEIP 469 (805)
1877 Q Consensus 405 geims----lsaatpkhlks-----igllspdfqedneteinf----llkqaltivgtlpftymlekwrw--mvfkgeip 469 (805)
1878 +..|. .+..++++|.. +|++++.-.++-...+|. ++++++..+. +|+.+++ +|+| -++.|+++
1879 T Consensus 309 S~~~E~~~~~~~~~~~~l~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~r~~~d~~~-~~~~~~~-~~~~e~~l~~~~~~ 386 (510)
1880 T 5WVU_C 309 SRTWENLVGRSLGFWERFFPRAREVFASLGDVSLEDFHFAVNAVEPSLIRVEADEVT-YNLHILV-RLELELALFRGELS 386 (510)
1881 T ss_dssp HHCCCCCCTTSHHHHHHHHHHHHHHCGGGTTCCHHHHHHHTTCCCCCSCSTTCCTTT-HHHHHHH-HHHHHHHHHHTSCC
1882 T ss_pred HHHHHHHhcCCHHHHHHHHHHHHHHhhccCCCCHHHHHHHHhccChhhhhHHhHHhH-hhHHHHH-HHHHHHHHhcCCCC
1883 Confidence 99998 66777777655 666544323333455666 7777777665 8998888 9999 89999999
1884
1885
1886 Q sp|Q9BYF1|ACE2 470 KDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSND--YSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDIS-- 545 (805)
1887 Q Consensus 470 kdqwmkkwwemkreivgvvepvphdetycdpaslfhvsnd--ysfiryytrtlyqfqfqealcqaakhegplhkcdis-- 545 (805)
1888 .+++-+.||++.++..|+..|. +...| ....|.+.. +.|.+|....++++|+.+++|+.. |+++.| +.
1889 T Consensus 387 ~~~l~~~w~~~~~~y~G~~~~~--~~~~~--~~~~h~~~~~~~Y~~~Y~~g~i~a~qi~~~~~~~~---~~~~~~-~~~~ 458 (510)
1890 T 5WVU_C 387 PEDLPEAWAEKYRDHLGVAPKD--YKDGV--MQDVHWAGGLFGYFPTYTLGNLYAAQFFQKAEAEL---GPLEPR-FARG 458 (510)
1891 T ss_dssp GGGHHHHHHHHHHHHHSCCCSS--STTTG--GGCSGGGGTCCSCTHHHHHHHHHHHHHHHHHHHHH---CCSHHH-HHTT
1892 T ss_pred hhhHhHHHHHHHHHHhCCCCCC--CCCCc--cccccccCCcccchHHHHHHHHHHHHHHHHHHHHH---CChhHH-hhcC
1893 Confidence 9999999999999999987553 23333 344555543 345588899999999999999876 489999 65
1894
1895
1896 Q sp|Q9BYF1|ACE2 546 NSTEAGQKLF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWL 595 (805)
1897 Q Consensus 546 nsteagqklf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwl 595 (805)
1898 +..++|+.|- ++++.|.+.+|.-.++.+.|. .++..+++.||++.+.-|
1899 T Consensus 459 ~~~~~g~~l~~~~l~~G~s~~~~ell~~~~G~-~l~~~~~l~~~~~~~~~~ 508 (510)
1900 T 5WVU_C 459 EFQPFLDWTRARIHAEGSRFRPRVLVERVTGE-APSARPFLAYLEKKYAAL 508 (510)
1901 T ss_dssp CCHHHHHHHHHHTGGGTTSSCHHHHHHHHHSS-CCCSHHHHHHHHHHHHHH
1902 T ss_pred CcHHHHHHHHHhHHHcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHH
1903 Confidence 4478999987 899999999999999999998 899999999999987644
1904
1905
1906 No 22
1907 >3SKS_A Putative Oligoendopeptidase F; Structural Genomics, Center for Structural; HET: PO4; 2.05A {Bacillus anthracis}
1908 Probab=100.00 E-value=1.7e-38 Score=300.72 Aligned_cols=506 Identities=15% Similarity=0.182 Sum_probs=375.4 Template_Neff=10.400
1909
1910 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQST-LA----QMYPLQEIQNLTVKLQ 96 (805)
1911 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst-la----qmyplqeiqnltvklq 96 (805)
1912 ++++..+|..++.....+-...+.++|.|.+++|.+..+.+.......+..+..... +. +--+++++.. ..+-+
1913 T Consensus 36 ~~~l~~~l~~~e~~~~~~~~~~~~a~~~~~~d~~d~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~l~~-~~~~~ 114 (567)
1914 T 3SKS_A 36 VEEQKQVIHSINEIRNDFGTMGNLCYIRHSVDTTDAFYKEEQDFFDEFSPVVQGYGTKYYNALIHSPFREELEA-YYGKQ 114 (567)
1915 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhHHhHHHHHHHHHHHhcChhHHHHHH-HHHHH
1916 Confidence 456778899999888888899999999999999999877665544444433322211 11 1112222211 12335
1917
1918
1919 Q sp|Q9BYF1|ACE2 97 LQALQQNGSSVLSEDKS---KRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG 173 (805)
1920 Q Consensus 97 lqalqqngssvlsedks---krlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg 173 (805)
1921 ++.+.+.+...++++.. ..++.+.+.+..++++.++|.++ +++.+ +.+..+|++ -|...|-.+|++|+...+
1922 T Consensus 115 l~~~~~~~~~~l~e~~e~~l~~~~~~~~~~~~~~~~~~~~~~g---~~~~~-~~~~~~l~~-~d~~~R~~~~~a~~~~~~ 189 (567)
1923 T 3SKS_A 115 LFALAECDLKTYSDEVVKDLQLENKLSSQYTQLLASAKIDFAG---EERTL-SQLIPFMQG-KERSERKAASEAYYGFLA 189 (567)
1924 T ss_pred HHHHHHHHhhcCCHHHHHHHHHHHHHHHHHHHHHhcCEEEeCC---EEEeH-HHHHHHHhC-CCHHHHHHHHHHHHHHHh
1925 Confidence 55566666666666422 23456668888999999999773 56666 889999996 899999999999998766
1926
1927
1928 Q sp|Q9BYF1|ACE2 174 K---QLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1929 Q Consensus 174 k---qlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1930 + .+++++.++|-+.+++|+.+.|.+|.+||.-.. .+.+|+...+..-++...++++|+|+.+|+++|.++-.
1931 T Consensus 190 ~~~~~~~~~l~~lv~~r~~~A~~~Gy~~~~~~~l~~~-----~~~~~~~~~~~~~l~~l~~~~~p~~~~~~~~~~~~lg~ 264 (567)
1932 T 3SKS_A 190 ENEEELDRIYDELVKVRTKIAKSLGFKNFVELGYARM-----YRTDYNAEMVANYRQQVLDYIVPVTTELRKRQQARIGV 264 (567)
1933 T ss_pred cCccchHHHHHHHHHHHHHHHHHcCCCCHHHHHHHHh-----hhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCC
1934 Confidence 5 579999999999999999999999999997432 23455555555566666777999999999998876510
1935
1936
1937 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFG-QKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLP------NM 323 (805)
1938 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfg-qkpnidvtdamvdqawdaqrifkeaekffvsvglp------nm 323 (805)
1939 .++ +.|...+.++ .+ ..| .+....+++.++.+|-+.|.. .|
1940 T Consensus 265 -------------~~l------~~~d~~~~~~--~~~~~~-----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 312 (567)
1941 T 3SKS_A 265 -------------EKL------AYYDENFEFP--TGNPTP-----------KGDADWIVNHGKTMYKELSAETDEFFNFM 312 (567)
1942 T ss_pred -------------CCC------CcccccCCCC--CCCCCC-----------CCCHHHHHHHHHHHHHhhCHHHHHHHHHH
1943 Confidence 011 3443333221 11 112 223457788888888888875 46
1944
1945
1946 Q sp|Q9BYF1|ACE2 324 TQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAA-QPFLLRNGANEGFHE 402 (805)
1947 Q Consensus 324 tqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaa-qpfllrnganegfhe 402 (805)
1948 ...+|-+ ....||....+.|++.. +.++++|+||...+.+|+.+.+|||||..+.+.... +|+..+. .+.+|+|
1949 T Consensus 313 ~~~~~iD-~~~r~~K~~g~~~~~~~---~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~-~~~~~~E 387 (567)
1950 T 3SKS_A 313 LDNDLLD-LVAKKGKAGGGYCTYIE---NYKAPFIFSNFNGTSGDIDVLTHEAGHAFQVYESRKFEIPEYNW-PTYEACE 387 (567)
1951 T ss_pred ccccccc-cCCCCCCCCCceeecCC---CCCCCEEEEeCCCCHHHHHHHHHHHHHHHHHHHccCCCCCCCCC-CCHHHHH
1952 Confidence 6667765 44556777778999854 457899999999999999999999999998887654 4554555 4568999
1953
1954
1955 Q sp|Q9BYF1|ACE2 403 AVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFK-GEIPKDQWMKKWWEMK 481 (805)
1956 Q Consensus 403 avgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfk-geipkdqwmkkwwemk 481 (805)
1957 +++..|.+....+ |... +..+. + ..++.+++..+.++|+.+++.+|+|.++. |+++.+++-+.||+..
1958 T Consensus 388 ~~S~~~E~l~~~~--l~~~------~~~~~--~-~~l~~~~~~~~~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~~~~ 456 (567)
1959 T 3SKS_A 388 IHSMSMEFFTWPW--MKLF------FEEDA--D-KYYFSHLSSALLFLPYGVSVDEYQHYVYENPEASPEERKTAWRNIE 456 (567)
1960 T ss_pred HHHHHHHHHhHHH--HHHh------CCCHH--H-HHHHHHHHHHHhHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
1961 Confidence 9999888877644 4321 11111 2 37888899999999999999999999997 8898899999999999
1962
1963
1964 Q sp|Q9BYF1|ACE2 482 REIVGVVEPVPHD--ETYCDPASLFHVS-NDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNML 558 (805)
1965 Q Consensus 482 reivgvvepvphd--etycdpaslfhvs-ndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml 558 (805)
1966 ++.-|++.|.+.+ +..+++++..|+. .....+.|....+.++|+.+.+|.. +.++|.++.++|
1967 T Consensus 457 ~~y~g~~~~~~~~~~~~~~~w~~~~h~~~~~~y~~~Y~~~~~~a~~l~~~~~~~--------------~~~~~~~~~~~l 522 (567)
1968 T 3SKS_A 457 KKYLPHRDYEDNDYLERGGFWQRQGHIYSSPFYYIDYTLAQICALQFWKRARDN--------------RQEAWEDYVNLC 522 (567)
1969 T ss_pred HHHCCCCCCCCCCCccccCChhhCCccccCCchHHHHHHHHHHHHHHHHHHHHc--------------cHHHHHHHHHHH
1970 Confidence 9999987776654 5677888888887 4677889999999999999999874 246789999999
1971
1972
1973 Q sp|Q9BYF1|ACE2 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNK 600 (805)
1974 Q Consensus 559 rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnk 600 (805)
1975 +.|.+.||.-.++.+.|.....-..+.+++++|-.|++.+|.
1976 T Consensus 523 ~~G~s~~~~e~l~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~ 564 (567)
1977 T 3SKS_A 523 QQGGSKSFLELVEVANLTSPFAEGCVKSVITEIEAWLHAIDD 564 (567)
1978 T ss_pred HccCCCCHHHHHHHcCCCCCCChhHHHHHHHHHHHHHHHhhh
1979 Confidence 999999999999988776555566788899999999987663
1980
1981
1982 No 23
1983 >3AHN_A Oligopeptidase; HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex; HET: ACT, 3A1; 1.8A {Geobacillus sp. MO-1}
1984 Probab=100.00 E-value=2.6e-38 Score=299.31 Aligned_cols=505 Identities=14% Similarity=0.150 Sum_probs=360.1 Template_Neff=10.400
1985
1986 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNN----AGDKWSAFLKEQ-STLAQMYPLQEIQNLTVKLQ 96 (805)
1987 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnn----agdkwsaflkeq-stlaqmyplqeiqnltvklq 96 (805)
1988 ++++..+++.++.....+-...++++|.|.+|+|.+..+.+.. ...++...+.+. ..+.+-..++ .+. +-.
1989 T Consensus 33 ~~~~~~~l~~~e~~~~~~~~~~~~a~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~---~~~-~~~ 108 (564)
1990 T 3AHN_A 33 AEEQNEAMKEINQLRNDFSTMAQICYIRHTIDTNDEFYKQEQDFFDEVEPIVKGLVNDYYRALVSSPFRS---QLE-GKW 108 (564)
1991 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCTTHH---HHH-HHH
1992 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCchHH---HHh-hhh
1993 Confidence 4677788888888888888999999999999999988775432 222333332211 0111100011 110 011
1994
1995
1996 Q sp|Q9BYF1|ACE2 97 LQALQQNGSSV--LSEDKSKRLNTILNTMSTIYS----TGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS 170 (805)
1997 Q Consensus 97 lqalqqngssv--lsedkskrlntilntmstiys----tgkvcnpdnpqeclllepglneimansldynerlwaweswrs 170 (805)
1998 +..+.+..... ..+++-..+......++..|+ +.++|-.+ +++.+ +.+..+|. +-|...|-.+|++|+.
1999 T Consensus 109 ~~~~~~~~~~~l~~~~~~~~~~~~~~~~l~~~y~~~~~~~~~~~~g---~~~~~-~~~~~~~~-~~d~~~R~~~~~~~~~ 183 (564)
2000 T 3AHN_A 109 GKQLFALAEAELKTYSPDIVEDLQLENKLTSEYTKLVASAKIFFEG---EERTL-AQLQPFVE-SPDRDMRKRASEARFT 183 (564)
2001 T ss_dssp CTHHHHHHHHHHTTCCGGGHHHHHHHHHHHHHHHHHHHTCCEEETT---EEECT-GGGHHHHT-CSSHHHHHHHHHHHHH
2002 T ss_pred HHHHHHHHHHHhhhcChhhHHHHHHHHHHHHHHHHHHhccEEEeCC---EEEeH-HHHHHHhc-CCCHHHHHHHHHHHHH
2003 Confidence 11111111111 223333444444556666666 88888542 35555 88999986 8899999999999999
2004
2005
2006 Q sp|Q9BYF1|ACE2 171 EVGK---QLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAK 247 (805)
2007 Q Consensus 171 evgk---qlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvrak 247 (805)
2008 ..++ .++++|.+.|-+++++|+.+.|.+|.+||...+. ..+++...+..-++...++++|+|+.+++++|..
2009 T Consensus 184 ~~~~~~~~~~~~~~~lv~~r~~~A~~~Gy~~~~~~~l~~~~-----~~~~~~e~~~~~~~~l~~~~~p~~~~~~~~~~~~ 258 (564)
2010 T 3AHN_A 184 FFQEHEEKFDEIYDQLVKVRTAIAQKLGFKNFVELGYARLG-----RTDYNAEMVAKFRKQVEKHIVPIAVKLRERQRER 258 (564)
2011 T ss_dssp HHHHTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHHHTT-----CCSCCHHHHHHHHHHHHHHTHHHHHHHHHHHHHH
2012 T ss_pred HHHHCHHHHHHHHHHHHHHHHHHHHHcCCCCHHHHHHHHcc-----cCCCCHHHHHHHHHHHHHhchHHHHHHHHHHHHH
2013 Confidence 8876 6999999999999999999999999999964321 1345555555556666778899999999988864
2014
2015
2016 Q sp|Q9BYF1|ACE2 248 LMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGF 327 (805)
2017 Q Consensus 248 lmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgf 327 (805)
2018 + |...-+.|... .||.....++. .++..+|+.++++|.+ ++.+...|
2019 T Consensus 259 l-------------------g~~~~~~~d~~----~~~~~~~~~~~--------~~~~~~~~~~~~~~~~--~~~~~~~~ 305 (564)
2020 T 3AHN_A 259 I-------------------GVEKLKYYDEA----FVFPTGNPMPK--------GDANWIIENGKKMYEE--LSPETGEF 305 (564)
2021 T ss_dssp H-------------------TCSSCCTTTTT----CCCTTCCCCCS--------SCHHHHHHHHHHHHHH--HCHHHHHH
2022 T ss_pred H-------------------Ccccccccccc----ccCCCCCCCCC--------CCHHHHHHHHHHHHHH--hCHHHHHH
2023 Confidence 3 32222334322 23332211111 1455677788888866 44455677
2024
2025
2026 Q sp|Q9BYF1|ACE2 328 WENSM-------LTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF 400 (805)
2027 Q Consensus 328 wensm-------ltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegf 400 (805)
2028 |++.. ...||....+.|++.. ..+++||+||...+++|+.+.+||+||.++.+.+..++.+..++.+.+|
2029 T Consensus 306 ~~~~~~~~~~D~~~r~~K~~g~~~~~~~---~~~~~~i~~n~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~ 382 (564)
2030 T 3AHN_A 306 FRYMIEHELMDLVAKKGKASGGYCTYIE---NYKAPFIFSNFTGTSGDIDVLTHEAGHAFQVYESRHYEIPEYNWPTLEA 382 (564)
2031 T ss_dssp HHHHHHTTCEEEECCTTCCSSCEEEEEG---GGTEEEEEEEECSSTHHHHHHHHHHHHHHHHHHTTTCSSGGGSSCCHHH
2032 T ss_pred HHHHHHcCCcccccCCCCCCCceeeeec---CCCCcEEEEcCCCChhHHHHHHHHHHHHHHHHHccCCCCccccCCcHHH
2033 Confidence 77652 2345555568999865 3577899999999999999999999999998877666655556788999
2034
2035
2036 Q sp|Q9BYF1|ACE2 401 HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFK-GEIPKDQWMKKWWE 479 (805)
2037 Q Consensus 401 heavgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfk-geipkdqwmkkwwe 479 (805)
2038 +|+.+..|.+....+ |+.. ++ +... ..++.+++.++..+|+.+++..|+|-++. |.++.+++-+.||+
2039 T Consensus 383 ~E~~s~~~e~l~~~~--l~~~--~~-----~~~~--~~~~~~l~~~~~~l~~~~~~~~fe~~ly~~~~~~~~~~~~~~~~ 451 (564)
2040 T 3AHN_A 383 CEIHSMSMEFFTWPW--MKLF--FK-----EDAE--KYQFYHLSDALLFLPYGVAVDEFQHFVYENPNATPAERKQAWRA 451 (564)
2041 T ss_dssp HHHHHHHHHHHTGGG--HHHH--HG-----GGHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCCHHHHHHHHHH
2042 T ss_pred HHHHHHHHHHhhHHH--HHHH--cc-----chHH--HHhHHHHHHHHHHHHHHHHHHHHHHHHHhCCCCCHHHHHHHHHH
2043 Confidence 999999988877644 4431 11 1111 13445566778889999999999999999 88888999999999
2044
2045
2046 Q sp|Q9BYF1|ACE2 480 MKREIVGVVEPVPHD--ETYCDPASLFHVSN-DYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFN 556 (805)
2047 Q Consensus 480 mkreivgvvepvphd--etycdpaslfhvsn-dysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfn 556 (805)
2048 +..+..|++.|.+.+ +..+++.+..|+.. ....+.|....+.++|+.+.+|+. +.++|.++.+
2049 T Consensus 452 ~~~~y~g~~~~~~~~~~~~~~~w~~~~H~~~~~~yy~~Y~~s~~~a~~l~~~~~~~--------------~~~~~~~~~~ 517 (564)
2050 T 3AHN_A 452 IERKYMPTKDYDGNDYLERGGFWQRQSHIYTTAFYYIDYTLAQICAFQFWKRSREN--------------YKEAWNDYLT 517 (564)
2051 T ss_dssp HHHHHSTTCCCTTCHHHHTTCGGGGCHHHHHSTTTTHHHHHHHHHHHHHHHHHHHC--------------HHHHHHHHHH
2052 T ss_pred HHHHHCCCCCCCCCchhhcCCChhhccchhcCchHHHHHHHHHHHHHHHHHHHHHh--------------HHHHHHHHHH
2053 Confidence 999998876665544 56778888889875 556788999999999999988865 2568999999
2054
2055
2056 Q sp|Q9BYF1|ACE2 557 MLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKN 601 (805)
2057 Q Consensus 557 mlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnkn 601 (805)
2058 +|+.|.+.||.-.++.+-|...+...+++.||+||..||+.+|+-
2059 T Consensus 518 ~l~~G~s~~~~e~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~ 562 (564)
2060 T 3AHN_A 518 LCRQGGSKPFTELVRVANLISPFEDGCVQSVVGGIEGWLNSVDDQ 562 (564)
2061 T ss_dssp HHTTTTSSCHHHHHHHTTCCCTTSTTHHHHHHHHHHHHHTTSCGG
2062 T ss_pred HHhcCCCCCHHHHHHHCCCCCCCChhHHHHHHHHHHHHHhccccc
2063 Confidence 999999999999999977767899999999999999999998864
2064
2065
2066 No 24
2067 >2QR4_A Peptidase M3B, oligoendopeptidase F; structural genomics, oligoendopeptidase F, PSI-2; 2.5A {Enterococcus faecium}
2068 Probab=99.95 E-value=2e-33 Score=267.60 Aligned_cols=506 Identities=14% Similarity=0.121 Sum_probs=318.6 Template_Neff=10.400
2069
2070 Q sp|Q9BYF1|ACE2 23 EQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNN-AGDKWSAFLKEQSTLAQM---YPLQ---E-----IQN 90 (805)
2071 Q Consensus 23 eqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnn-agdkwsaflkeqstlaqm---yplq---e-----iqn 90 (805)
2072 +..+.+|+.++.....+-...+.+.|.+.++++.+..+.+.. ...+.+.+.+..+.+.+. .|.. + .+.
2073 T Consensus 34 ~~l~~~l~~~e~~~~~l~~~~~ya~~~~~~d~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~l~~~~~l 113 (587)
2074 T 2QR4_A 34 SQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSLFSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKL 113 (587)
2075 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCHHHHHHHHHHHHHHHHHHHHTTTHHHHHTTSCHHHHHHHHHHCGGG
2076 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHhcchhHHHHcCCHHHHHHHHHhChhh
2077 Confidence 455666777777777788889999999999999986665443 333333333322222111 1111 1 112
2078
2079
2080 Q sp|Q9BYF1|ACE2 91 LTVKLQLQALQQNGSSVLSEDKSKRLNTI---LNTMSTIYSTG---KVCNPD----NPQECLLLEPGLNEIMANSLDYNE 160 (805)
2081 Q Consensus 91 ltvklqlqalqqngssvlsedkskrlnti---lntmstiystg---kvcnpd----npqeclllepglneimansldyne 160 (805)
2082 -..+-.|+.+.+.+...|+++..+.+.++ ++.++.+|++- .+|-++ +..++-+-.+.+..+|+ +-|...
2083 T Consensus 114 ~~~~~~l~~~~~~~~~~Ls~~~e~~l~~~~~~~~~~~~~y~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~~l~-~~d~~~ 192 (587)
2084 T 2QR4_A 114 EVYRHYIQQIVDNRAHVLSAEQESLLAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLE-STDRRV 192 (587)
2085 T ss_dssp GGGHHHHHHHHTTGGGCCCHHHHHHHHHTHHHHHHHHHHHHHCCCCCCCCCEEECTTSCEEECCHHHHHHHHT-CSCHHH
2086 T ss_pred HhhHHHHHHHHHcCCcCCCHHHHHHHHHHhhhhHHHHHHHHHHHhhccccCcccCCCCcEEEcCHHHHHHHhh-CCCHHH
2087 Confidence 25566777788888899999988877666 77888899884 666552 23333333456888999 899999
2088
2089
2090 Q sp|Q9BYF1|ACE2 161 RLWAWESWRSEVG---KQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLY 237 (805)
2091 Q Consensus 161 rlwaweswrsevg---kqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikply 237 (805)
2092 |..+|++|++..+ ..+.++|.+++.+.+++|+.+.|.+|.+||..++++. -+.++..++.|++++
2093 T Consensus 193 R~~~~~a~~~~~~~~~~~~~~~l~~lv~~~~~~A~~~Gy~~~~~~~l~~~~~~------------~~~~~~l~~~i~~~~ 260 (587)
2094 T 2QR4_A 193 REAAFKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIP------------ESVYDTLVDVVNKHL 260 (587)
2095 T ss_dssp HHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHHTTTCC------------HHHHHHHHHHHHHTH
2096 T ss_pred HHHHHHHHHHHHHHhHHHHHHHHHHHHHhhHHHHHHcCCCCHHHHHHhhcCCC------------HHHHHHHHHHHHHhh
2097 Confidence 9999999998876 4899999999999999999999999999997765531 144557788999999
2098
2099
2100 Q sp|Q9BYF1|ACE2 238 EHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQ--KPNIDVTDAMVDQAWDA-----QRIFKE 310 (805)
2101 Q Consensus 238 ehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgq--kpnidvtdamvdqawda-----qrifke 310 (805)
2102 ..+|+|+|.++.. + |. + . -+.|.. | .|+.. .+.+++ +..++....+ ..+++-
2103 T Consensus 261 ~~~~~~~~~~~~~-~-------g~-~-~------l~~~D~-~---~~~~~~~~~~~~~-~e~~~~~~~~~~~~~~~~~~~ 319 (587)
2104 T 2QR4_A 261 PLLHRYMELRKRL-L-------EV-E-K------LHMYDL-Y---TPVLGEAPITFTY-EEAKEKALEALKPMGEEYMAI 319 (587)
2105 T ss_dssp HHHHHHHHHHHHH-H-------TC-S-S------BCGGGS-S---SCSSCCCCC------CCHHHHHHHTGGGHHHHHHC
2106 T ss_pred HHHHHHHHHHHHH-h-------CC-C-C------cchhhc-C---CCCCCCCCCccCH-HHHHHHHHHHhHhhCHHHHHH
2107 Confidence 9999999876542 1 11 0 0 022322 1 22222 244554 2233332222 234444
2108
2109
2110 Q sp|Q9BYF1|ACE2 311 AEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYA-AQP 389 (805)
2111 Q Consensus 311 aekffvsvglpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmaya-aqp 389 (805)
2112 ++++| +.| |-. +...||....+.|++.. .++++|+||...+.+|+.|.+||+||..+.+... .+|
2113 T Consensus 320 ~~~~~-~~~--------~id-~~~r~~K~~g~~~~~~~----~~~~~I~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~ 385 (587)
2114 T 2QR4_A 320 VEKAF-SER--------WID-VVENKGKRSGAYSSGSY----DTNPYILLNWHDTLDQLFTLVHEMGHSVHSYFTRSNQP 385 (587)
2115 T ss_dssp ------------------------------------------------------CHHHHHHHHHHHHHHHHHHHC-----
2116 T ss_pred HHHHH-HcC--------CeE-eecCCCCCCCceecCCC----CCCcEEEeecCCChHHHHHHHHHHHHHHHHHHhhcCCC
2117 Confidence 55544 333 211 11134555567787643 3589999999999999999999999999988776 678
2118
2119
2120 Q sp|Q9BYF1|ACE2 390 FLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTI-VGTLPFTYMLEKWRWMVFKG-- 466 (805)
2121 Q Consensus 390 fllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqalti-vgtlpftymlekwrwmvfkg-- 466 (805)
2122 .+.+. .+.+|+|+++..|..-... + |+. .+ +...+++.+++++++- +++++...+...|.+-++.+
2123 T Consensus 386 ~~~~~-~~~~~~E~~S~~~E~l~~~--~-----L~~-~~--~~~~~~~~l~~~~l~~~~~~l~~~~~~~~fe~~~~~~~~ 454 (587)
2124 T 2QR4_A 386 YVYGD-YSIFLAEIASTTNENILTE--Y-----LLE-TE--KDPRVRAYVLNHYLDGFKGTVFRQTQFAEFEHFMHTEDE 454 (587)
2125 T ss_dssp --------CHHHHHHHHHHHHHHHH--H-----HHH-HC--CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
2126 T ss_pred hhhcc-CcHHHHHHHHHHHHHHHHH--H-----HHH-hC--CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2127 Confidence 87775 6778888888777654322 2 321 11 1223478888888763 67888888888888888876
2128
2129
2130 Q sp|Q9BYF1|ACE2 467 ---EIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCD 543 (805)
2131 Q Consensus 467 ---eipkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcd 543 (805)
2132 .++.+.+.+-||+..++..|+..|.. ++..++....+|....|-...|..-.+.++|+.+.+|+.
2133 T Consensus 455 ~~~~l~~~~l~~~~~~~~~~~~g~~~~~~-~~~~~~w~~~~h~~~~~Y~~~y~~~~~~~~~l~~~~~~~----------- 522 (587)
2134 T 2QR4_A 455 KGVPLTSEYLSDSYGKLNAKYYGPAVEED-PEIKFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQ----------- 522 (587)
2135 T ss_dssp TTCCCCHHHHHHHHHHHHHHHHCTTBCCC-GGGGGGGGGCGGGGSSSCTHHHHHHHHHHHHHHHHHHTT-----------
2136 T ss_pred cCCCCCHHHHHHHHHHHHHHHhCCCCCCC-hhhccHhHcCcchhcccccHHHHHHHHHHHHHHHHHHhc-----------
2137 Confidence 56678899999999999999876653 334556666677664444455555566677777777762
2138
2139
2140 Q sp|Q9BYF1|ACE2 544 ISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSF 603 (805)
2141 Q Consensus 544 isnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsf 603 (805)
2142 +.++|.++..+|+.|.+.||.-.++. +|.......++..+|.|+-.||+..++..-
2143 T Consensus 523 ---~~~~~~~~~~~l~~G~s~~~~ell~~-~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~ 578 (587)
2144 T 2QR4_A 523 ---EPEALENYLAYLKAGNSDYPVEVMKK-AGVDMTQAAYIEDAMSMFEQRLNELEELID 578 (587)
2145 T ss_dssp ---CTTHHHHHHHHHHHCSCSCHHHHHHH-TTCCTTSSHHHHHHHHHHHHHHHHHHHHHH
2146 T ss_pred ---ChHHHHHHHHHHHcCCCCCHHHHHHH-cCCCCCCcHHHHHHHHHHHHHHHHHHHHHH
2147 Confidence 36789999999999999999999997 999988888999999999999998876543
2148
2149
2150 No 25
2151 >2O36_A Thimet oligopeptidase (E.C.3.4.24.15); thermolysin-like domain, substrate-binding channel, HYDROLASE; 1.95A {Homo sapiens}
2152 Probab=99.92 E-value=5e-30 Score=254.55 Aligned_cols=518 Identities=16% Similarity=0.181 Sum_probs=335.6 Template_Neff=9.600
2153
2154 Q sp|Q9BYF1|ACE2 26 KTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP-------------LQEIQNLT 92 (805)
2155 Q Consensus 26 ktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp-------------lqeiqnlt 92 (805)
2156 ..++..++.....+....++++|.++++++++..+....+-.++++|..+..+-...|. +.+.+...
2157 T Consensus 47 ~~~v~~~d~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~ld~e~~r~ 126 (674)
2158 T 2O36_A 47 ESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 126 (674)
2159 T ss_dssp CCCCCHHHHHHHHHHHHHHHHHSHHHHCSCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHHHHSCTTCSCHHHHHH
2160 T ss_pred HHHHHHHHHhhHHHHHHHHHHhHHHHhCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHHHhhchhcCCHHHHHH
2161 Confidence 34566666667777888999999999999999999999999999999999877666665 23333445
2162
2163
2164 Q sp|Q9BYF1|ACE2 93 VKLQLQALQQNGSSVLSEDKSKRLNTI---LNTMSTIYSTGKVCNPD-------------------------NPQECLLL 144 (805)
2165 Q Consensus 93 vklqlqalqqngssvlsedkskrlnti---lntmstiystgkvcnpd-------------------------npqeclll 144 (805)
2166 ++..++.++++|.. |++++.+++..+ ++.+++.|+....|.+. .+ -++.+
2167 T Consensus 127 l~~~l~~~~~~G~~-L~~~~~~~~~~l~~~i~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~~-~~~~l 204 (674)
2168 T 2O36_A 127 LERLIKLGRRNGLH-LPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGK-LKVTL 204 (674)
2169 T ss_dssp HHHHHHHHHHTTTT-SCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECTTTTTTSCHHHHTTSEECTTSC-EEEES
2170 T ss_pred HHHHHHHHHHcCCC-CCHHHHHHHHHHHHHHHHHHHHHHHccCCCccccceeHHHhcCCCHHHHHHHHhhhCCC-EEEec
2171 Confidence 66677788888865 666565666555 55578888888777643 12 13333
2172
2173
2174 Q sp|Q9BYF1|ACE2 145 -EPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLI 223 (805)
2175 Q Consensus 145 -epglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqli 223 (805)
2176 .|.+..+|+++-|...|..+|+.|+...++...+++++.+.+++++|+...|.+|.+||..+..+ .+..++.
2177 T Consensus 205 ~~~~~~~il~~~~d~~~R~~~~~a~~~~~~~~~~~~l~~ll~lR~~~A~llGy~s~~~~~l~~~~~-------~~~~~v~ 277 (674)
2178 T 2O36_A 205 KYPHYFPLLKKCHVPETRRKVEEAFNSRCKEENSAILKELVTLRAQKSRLLGFHTHADYVLEMNMA-------KTSQTVA 277 (674)
2179 T ss_dssp SHHHHHHHHHHCCCHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSTT-------CSHHHHH
2180 T ss_pred CChhhHHHHhhCCCHHHHHHHHHHHHcCCchHHHHHHHHHHHHHHHHHHHhCCCCHHHHHhhccCC-------CCHHHHH
2181 Confidence 57789999999999999999999998877788999999999999999999999999999764332 2233444
2182
2183
2184 Q sp|Q9BYF1|ACE2 224 EDVEHTFEEIKPLYEHLHAYVRAK---LMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQ 300 (805)
2185 Q Consensus 224 edvehtfeeikplyehlhayvrak---lmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdq 300 (805)
2186 +-++...+.++|+|+..++.+++. ....+.. +..+.+ ..|...|-...... ...++.++.+.+
2187 T Consensus 278 ~~l~~l~~~~~p~~~~~~~~l~~~~~~~~~~~g~--~~~~~l----------~~wD~~y~~~~~~~--~~~~~~~~~~~~ 343 (674)
2188 T 2O36_A 278 TFLDELAQKLKPLGEQERAVILELKRAECERRGL--PFDGRI----------RAWDMRYYMNQVEE--TRYCVDQNLLKE 343 (674)
2189 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTC--CCCSSC----------CTTTHHHHHHHHCC--CCCCCCHHHHGG
2190 T ss_pred HHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHCCC--CCCCCC----------ChhcHHHHHHHHHH--hccCCCHHHHHh
2191 Confidence 445555678899998876655442 2222210 001111 23444444443322 234444555555
2192
2193
2194 Q sp|Q9BYF1|ACE2 301 AWD----AQRIFKEAEKFFVSVGLPNM---TQGFWENSML-----------------T----DPGNVQKAVCHPTAWDLG 352 (805)
2195 Q Consensus 301 awd----aqrifkeaekffvsvglpnm---tqgfwensml-----------------t----dpgnvqkavchptawdlg 352 (805)
2196 .+. ...+++.++++| |+.-. ..-+|..+.. . .||....+.|++...+..
2197 T Consensus 344 yf~~~~v~~~l~~~~~~~f---g~~~~~~~~~~~W~~~v~~~~v~d~~~~~~lg~~ylD~~~r~~K~~~a~~~~~~~~~~ 420 (674)
2198 T 2O36_A 344 YFPVQVVTHGLLGIYQELL---GLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL 420 (674)
2199 T ss_dssp GCBHHHHHHHHHHHHHHHH---TEEEEECTTCCCSSTTCEEEEEEETTTCCEEEEEEEECSCCTTSCCSCEEEEEECCEE
2200 T ss_pred hCCHHHHHHHHHHHHHHHh---CcEEEeCCCCCcccCCceEEEEEeCCCCcEEEEEEEeCCCCCCCCCCCceeeEeCCcc
2201 Confidence 443 245666666666 43221 2345665553 1 234433455554332211
2202
2203
2204 Q sp|Q9BYF1|ACE2 353 K--GDF-----RI---------LMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEG--FHEAVGEIMSLSAAT 414 (805)
2205 Q Consensus 353 k--gdf-----ri---------lmctkvtmddfltahhemghiqydmayaaqpfllrnganeg--fheavgeimslsaat 414 (805)
2206 . |+. .| -.|+.++++|+.|.+||+||..+.+.+..++..+ .|.+-+ |+|+++.+|.+.+..
2207 T Consensus 421 ~~~~~~~~P~~~i~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~~~-~g~~~~~d~~E~~S~~~E~~~~~ 499 (674)
2208 T 2O36_A 421 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVRTYFHEFGHVMHQLCSQAEFAMF-SGTHVETDFVEAPSQMLENWVWE 499 (674)
2209 T ss_dssp CTTSCEECEEEEEECCCCCCBTTBCCBCCHHHHHHHHHHHHHHHHHHHCCCSSGGG-STTCSCTTTTTHHHHHHHGGGGS
2210 T ss_pred cCCCCeeceEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhcCCcccc-cCCcccchhhcchhHHHHHhhcC
2211 Confidence 0 111 22 1578888999999999999999999988766554 566655 999999999999999
2212
2213
2214 Q sp|Q9BYF1|ACE2 415 PKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIP---KDQWMKKWWEMKREIVGVVEPV 491 (805)
2215 Q Consensus 415 pkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeip---kdqwmkkwwemkreivgvvepv 491 (805)
2216 |++|+.++.-..+-+.-.+..++.++.. ....+..++++.+.+-.|..++- .+++.+.||++.++..|+ |+
2217 T Consensus 500 ~~~L~~l~~~~~~~~~l~~~~~~~l~~~----~~~~~~~~~~~~~~~~~~d~~l~~~~~~~~~~~~~~l~~~~~g~--~~ 573 (674)
2218 T 2O36_A 500 QEPLLRMSRHYRTGSAVPRELLEKLIES----RQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGV--PA 573 (674)
2219 T ss_dssp HHHHHHTCCCTTTCCCCCHHHHHHHHHG----GGTTHHHHHHHHHHHHHHHHHHTTCSSCCHHHHHHHHCCCCCSS--CC
2220 T ss_pred hHHHHHHcccCCCCCCCCHHHHHHHHHH----hhHhHHHHHHHHHHHHHHHHHHhCCCCCCHHHHHHHHHHHHhCC--CC
2221 Confidence 9999988743221111112233333321 11222222333444434433332 356889999999999887 33
2222
2223
2224 Q sp|Q9BYF1|ACE2 492 PHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQ-AAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLA 569 (805)
2225 Q Consensus 492 phdetycdpaslfhvsndysfiryytrtlyqfqfqealcq-aakhegplhkcdisnsteagqklf-nmlrlgksepwtla 569 (805)
2226 +. ...++.+..|+..+|.+ .|| .-++..-+...+.+ ..+..||+ +.++|.++. ++|..|.+.+|.-.
2227 T Consensus 574 ~~--~~~~~~~~~Hl~~~y~~-~yy-~Yl~s~vlA~~i~~~~f~~~~~~-------~~~~g~~~~~~~L~~G~s~~~~e~ 642 (674)
2228 T 2O36_A 574 TP--GTNMPATFGHLAGGYDA-QYY-GYLWSEVYSMDMFHTRFKQEGVL-------NSKVGMDYRSCILRPGGSEDASAM 642 (674)
2229 T ss_dssp CT--TCCGGGGCGGGGTTCTT-CTT-HHHHHHHHHHHHCCCCCCHHCTT-------CHHHHHHHCCCCCTTGGGSCHHHH
2230 T ss_pred CC--CCCCcccHHHHHhcchH-HHH-HHHHHHHHHHHHHHHHHHhhCCC-------CHHHHHHHHHhccccCCCcCHHHH
2231 Confidence 32 24577888898766655 344 22222111111111 11223343 458899999 89999999999999
2232
2233
2234 Q sp|Q9BYF1|ACE2 570 LENVVGAKNMNVRPLLNYF 588 (805)
2235 Q Consensus 570 lenvvgaknmnvrpllnyf 588 (805)
2236 ++++.|. .++..+++.++
2237 T Consensus 643 l~~~lG~-~~~~~~~l~~~ 660 (674)
2238 T 2O36_A 643 LRRFLGR-DPKQDAFLLSK 660 (674)
2239 T ss_dssp HHHHHSS-CCCSHHHHHHT
2240 T ss_pred HHHHhCC-CCCHHHHHHHc
2241 Confidence 9999995 78888888765
2242
2243
2244 No 26
2245 >3CE2_A Crystal structure of putative peptidase; structural genomics, UNKNOWN FUNCTION, putative; 2.6A {Chlamydophila abortus}
2246 Probab=99.92 E-value=1.1e-29 Score=244.31 Aligned_cols=507 Identities=15% Similarity=0.108 Sum_probs=330.6 Template_Neff=10.300
2247
2248 Q sp|Q9BYF1|ACE2 23 EQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGD-KWSAFLKEQSTL---AQMYPLQEI-------QNL 91 (805)
2249 Q Consensus 23 eqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagd-kwsaflkeqstl---aqmyplqei-------qnl 91 (805)
2250 +..+.+++.+......+-...+.+++.+.++.+.+..+.+.+... ..+.+...-+.+ .+..+-+++ +.-
2251 T Consensus 67 ~~~~~~l~~~e~~~~~l~~~~~~a~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~l~~~~~~ 146 (618)
2252 T 3CE2_A 67 ESLLSLLTTLFSIERKLNKLYVYAHLTHDQDITNQEGIADLKSITHLHTLFAEETSWVQPALTSLSESLIAQHLSAPCLA 146 (618)
2253 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCHHHHHHHHHHHHHHHHHHHHTTTHHHHHHTSCHHHHHHHHHCSTTG
2254 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHhhhhhHHHHhcCCHHHHHHHhcCccch
2255 Confidence 455667777777778888889999999999998876665554333 222222211111 011111111 223
2256
2257
2258 Q sp|Q9BYF1|ACE2 92 TVKLQLQALQQNGSSVLSEDKSKRLNTI---LNTMSTIYST---GKVCNPD---NPQECLLLEPG-LNEIMANSLDYNER 161 (805)
2259 Q Consensus 92 tvklqlqalqqngssvlsedkskrlnti---lntmstiyst---gkvcnpd---npqeclllepg-lneimansldyner 161 (805)
2260 ..+..|+.+...+...|++++.+++..+ +..++.+|++ ..+|-+. ...+++-+.++ ...+|. +-|...|
2261 T Consensus 147 ~~~~~l~~~~~~~~~~Ls~~~e~~l~~l~~~l~~~~~~~~~l~~~~~~~~~~~~~~g~~~~l~~~~~~~~l~-~~d~~~R 225 (618)
2262 T 3CE2_A 147 PYRFYLEKIFRLSIHTGTPGEEKILASAFTPLEVASKAFSSLSDSEIPFGQATDSEGNSHPLSHALASLYMQ-STDRELR 225 (618)
2263 T ss_dssp GGHHHHHHHHTTGGGCCCHHHHHHHHHHTTGGGHHHHHHHCCCCCCSCCCEEECSSCCEEECCHHHHHHHHT-CSCHHHH
2264 T ss_pred hhHHHHHHHHHhCCccCCHHHHHHHHHhcChhHHHHHHHHHHHcccccccceeCCCCCEEECCHHHHHHHcc-CCCHHHH
2265 Confidence 4566777766667777888877665544 4466666765 4555431 12245555655 677777 8899999
2266
2267
2268 Q sp|Q9BYF1|ACE2 162 LWAWESWRSEV---GKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYE 238 (805)
2269 Q Consensus 162 lwaweswrsev---gkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplye 238 (805)
2270 --+|+.|.... .....+++.+.+-+++++|+...|.+|.+|+..+++++ -+.++..++.|++++.
2271 T Consensus 226 k~~~~a~~~~~~~~~~~~~~~l~~l~~~r~~~A~~~Gy~s~~~~~l~~~~~~------------~~~~~~l~~~v~~~~~ 293 (618)
2272 T 3CE2_A 226 KTSYLAQCERYHSYRHTFANLLNGKIQAHVFYAKNKRYNSCLQAALYHNNIP------------TTVYTNLIDIVKKNSS 293 (618)
2273 T ss_dssp HHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTTTCC------------HHHHHHHHHHHHTTHH
2274 T ss_pred HHHHHHHHHHHHhcHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHhcCCC------------HHHHHHHHHHHHHchH
2275 Confidence 99999998764 35688899999999999999999999999997654431 2566678888899999
2276
2277
2278 Q sp|Q9BYF1|ACE2 239 HLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQ--KPNIDVTDAMVDQAWDAQRIFKEAEKFFV 316 (805)
2279 Q Consensus 239 hlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgq--kpnidvtdamvdqawdaqrifkeaekffv 316 (805)
2280 .+|+|++.+.... |.-+-..|...| |+.+ ++.+++.++. ..+++....++.
2281 T Consensus 294 ~~~~~~~~~~~~~----------------g~~~l~~wD~~~----~~~~~~~~~~~~~~~~-------~~v~~~l~~~~~ 346 (618)
2282 T 3CE2_A 294 LITKYFSIKQRCL----------------NLKDFHFYDVYA----PLSQSKEKKYTFQEAV-------DLIYTSLSPLGT 346 (618)
2283 T ss_dssp HHHHHHHHHHHHH----------------TCSSCBGGGTTC----CSCC--CCCCCHHHHH-------HHHHHHTGGGHH
2284 T ss_pred HHHHHHHHHHHHc----------------CCCCcchhhhcC----CCCcccCCccCHHHHH-------HHHHHHhhhcCH
2285 Confidence 9999999876531 222444554444 3332 3455554431 122222222221
2286
2287
2288 Q sp|Q9BYF1|ACE2 317 SVGLPNMTQGFWENSM---LTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYA-AQPFLL 392 (805)
2289 Q Consensus 317 svglpnmtqgfwensm---ltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmaya-aqpfll 392 (805)
2290 .++- .+...|+.+.. ...||....+.|++.. .++.+|+||...+++|+.|.+||+||..+.+.+. .+|+..
2291 T Consensus 347 ~~~~-~~~~~~~~~~~iD~~~r~~K~~ga~~~~~~----~~~~~I~~n~~~~~~~~~tl~HElGHa~h~~~~~~~~~~~~ 421 (618)
2292 T 3CE2_A 347 EYID-TLKQGLTTQGWVDKYENLNKRSGAYSSGCY----DSHPYVLLNYTGTLYDVSVIAHEGGHSMHSYFSRKHQPFHD 421 (618)
2293 T ss_dssp HHHH-HHHHHHHTSCCEECSCCTTCCCSCEEECCT----TSCCEEECCCCSSHHHHHHHHHHHHHHHHHHHHHHHSCGGG
2294 T ss_pred HHHH-HHHHHHhhcCceecccCCCCCCCccccCCC----CCCcEEEEecCCCchHHHHHHHHHHHHHHHHHHHhcCchhh
2295 Confidence 1110 01112322222 2234555667887632 2578999999999999999999999999998776 478876
2296
2297
2298 Q sp|Q9BYF1|ACE2 393 RNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALT-IVGTLPFTYMLEKWRWMVF----KG- 466 (805)
2299 Q Consensus 393 rnganegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqalt-ivgtlpftymlekwrwmvf----kg- 466 (805)
2300 +. ...+|+|+++..|.+-...+. ++ +.. +.+..++ ++.+.+. ++.+++...+...|..-++ .|
2301 T Consensus 422 ~~-~~~~~~E~~S~~~E~l~~~~~-~~-------~~~-~~~~~~~-~l~~~l~~~~~~~~~~~~~~~fe~~l~~~~~~~~ 490 (618)
2302 T 3CE2_A 422 AQ-YPIFLAEIASTLNEMLLMDSM-LK-------ESD-SKEEKIT-ILTRCLDTIFSTLFRQVLFASFEYDIHHAAEHGV 490 (618)
2303 T ss_dssp CS-CCGGGTTHHHHHHHHHHHHHH-HH-------HCC-CHHHHHH-HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHTTC
2304 T ss_pred cC-CCHHHHHHHHHHHHHHhHHHH-Hh-------hCC-CHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCC
2305 Confidence 64 456899999888876655442 11 111 1122344 4444444 4446666655555555555 45
2306
2307
2308 Q sp|Q9BYF1|ACE2 467 EIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN 546 (805)
2309 Q Consensus 467 eipkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisn 546 (805)
2310 +++.+++.+.||++.++..|+..|.+ ++..+++++..|+-..|-...|..-.+..+++.+.+|. +
2311 T Consensus 491 ~l~~~~l~~~~~~~~~~~~g~~~~~~-~~~~~~w~~~~h~~~~~Y~y~y~~~~~~a~~l~~~~~~--------------~ 555 (618)
2312 T 3CE2_A 491 PLTEEYLSSTYKNLQNEFYGEIITFD-VLSNIEWARIPHFYYNFYVYQYATGIIAALCFLEKILN--------------N 555 (618)
2313 T ss_dssp CCCHHHHHHHHHHHHHHHHTTTCBCC-TTGGGGGGGSCGGGCSSCTHHHHHHHHHHHHHHHHHHT--------------T
2314 T ss_pred CCCHHHHHHHHHHHHHHHhCCCCCCc-cccccHhhccchhhcchhcHHHHHHHHHHHHHHHHHHh--------------C
2315 Confidence 67778999999999999999877665 35566777777764222222222223444555444432 3
2316
2317
2318 Q sp|Q9BYF1|ACE2 547 STEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKN 601 (805)
2319 Q Consensus 547 steagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnkn 601 (805)
2320 ..++|.++.++|+.|.+.||.-.++. .|.......++..+|.|+..||+..++.
2321 T Consensus 556 ~~~~~~~~~~~L~~G~s~~~~el~~~-~g~~~~~~~~~~~~~~~l~~~l~~~~~~ 609 (618)
2322 T 3CE2_A 556 EDNALNSYLNFLKSGGSDFPLEILKK-SGLDMGTVEPIQKAFCFIEKKIQELSSL 609 (618)
2323 T ss_dssp CTTHHHHHHHHHTTTTSSCHHHHHHH-TTCCTTSSHHHHHHHHHHHHHHHHHHTT
2324 T ss_pred CchHHHHHHHHHHccCCCCHHHHHHH-cCCCCCCCHHHHHHHHHHHHHHHHHHHH
2325 Confidence 46789999999999999999999984 9999888999999999999999988764
2326
2327
2328 No 27
2329 >2O3E_A Neurolysin (E.C.3.4.24.16); thermolysin-like domain, substrate-binding channel, HYDROLASE; 2.2A {Rattus norvegicus}
2330 Probab=99.90 E-value=9.4e-29 Score=246.41 Aligned_cols=515 Identities=14% Similarity=0.179 Sum_probs=346.7 Template_Neff=9.500
2331
2332 Q sp|Q9BYF1|ACE2 31 KFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMY-------------PLQEIQNLTVKLQL 97 (805)
2333 Q Consensus 31 kfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmy-------------plqeiqnltvklql 97 (805)
2334 .+......+-...+.++|-+.++.+++..+..+.+..+++++..+..+-...| .+.+.+...++..+
2335 T Consensus 68 ~ld~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~ly~~l~~~~~~~~~~~ld~e~~~~l~~~~ 147 (678)
2336 T 2O3E_A 68 VLADIEVTYIVERTMLDFPQHVSSDREVRAASTEADKKLSRFDIEMSMREDVFQRIVHLQETCDLEKIKPEARRYLEKSI 147 (678)
2337 T ss_dssp HHHHHHHHHHHHHHHHHSHHHHCSCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHHHHCCTTSSCHHHHHHHHHHH
2338 T ss_pred HHHHhhhhhHHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHHhcccHhhCCHHHHHHHHHHH
2339 Confidence 33333333556677888999999999999999999999999988875544444 35555666778888
2340
2341
2342 Q sp|Q9BYF1|ACE2 98 QALQQNGSSVLSEDKSKRLNTI---LNTMSTIYSTGKVCNPD-------------------------NPQECLLL-EPGL 148 (805)
2343 Q Consensus 98 qalqqngssvlsedkskrlnti---lntmstiystgkvcnpd-------------------------npqeclll-epgl 148 (805)
2344 +.++++|.. |++++.+++..+ +..++..|+....|... .+ .++.+ .|.+
2345 T Consensus 148 ~~~~~~G~~-L~~~~~~~~~~l~~~i~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~g-~~~~l~~~~~ 225 (678)
2346 T 2O3E_A 148 KMGKRNGLH-LSEHIRNEIKSMKKRMSELCIDFNKNLNEDDTSLVFSKAELGALPDDFIDSLEKTDEDK-YKVTLKYPHY 225 (678)
2347 T ss_dssp HHHHHTTTT-SCHHHHHHTHHHHHHHHHHHHHHHHHHHHCCCEEEEETTTTTTCCHHHHHTSCBCSSSE-EEEESSHHHH
2348 T ss_pred HHHHHcCCC-CCHHHHHHHHHHHHHHHHHHHHHHHhcCCCCcceeCCHHHHcCCCHHHHHHHhcCCCCC-cEEEcCCccH
2349 Confidence 899999975 777666666544 44555556666665421 12 23444 5678
2350
2351
2352 Q sp|Q9BYF1|ACE2 149 NEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEH 228 (805)
2353 Q Consensus 149 neimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedveh 228 (805)
2354 ..+|+++-|...|..+|+.|....++..++++++.+.+++++|+...|++|.+||..++.+ ++..++.+-.+.
2355 T Consensus 226 ~~il~~~~d~~~R~~~~~a~~~~~~~~~~~~l~~ll~lr~~~A~~lGy~s~~~~~l~~~~~-------~s~~~v~~~l~~ 298 (678)
2356 T 2O3E_A 226 FPVMKKCCVPETRRKMEMAFHTRCKQENTAILQQLLPLRAQVAKLLGYNTHADFVLELNTA-------KSTSRVAAFLDD 298 (678)
2357 T ss_dssp HHHHHHCCCHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSTT-------CSHHHHHHHHHH
2358 T ss_pred HHHHHhCCCHHHHHHHHHHhhcCCchhHHHHHHHHHHHHHHHHHHhCCCCHHHHHhccCCC-------CCHHHHHHHHHH
2359 Confidence 8999999999999999999998777788999999999999999999999999999876643 233445555666
2360
2361
2362 Q sp|Q9BYF1|ACE2 229 TFEEIKPLYEHLHAYVRAKLMNAYPSY-ISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRI 307 (805)
2363 Q Consensus 229 tfeeikplyehlhayvraklmnaypsy-ispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqri 307 (805)
2364 ..+.++|++++++++++.......+.+ .++.+.+ ..|...|-...+. +...+++++.+.+-+....+
2365 T Consensus 299 l~~~~~p~~~~~~~~l~~~~~~~~~~~g~~~~~~l----------~~wD~~~~~~~~~--~~~~~~~~~~~~~yf~~~~v 366 (678)
2366 T 2O3E_A 299 LSQKLKPLGEAEREFILSLKKKECEERGFEYDGKI----------NAWDLHYYMTQTE--ELKYSVDQESLKEYFPIEVV 366 (678)
2367 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCSSC----------CHHHHHHHHHHHH--HHHTCCCHHHHGGGCBHHHH
2368 T ss_pred HHHHhHHHHHHHHHHHHHHHHHHhHHcCCCcCCCC----------CcccHHHHHHHHH--HhcCCCCHHHHHhhCCHHHH
2369 Confidence 778899999999999987443322211 1111122 3455555554433 22455656666655555444
2370
2371
2372 Q sp|Q9BYF1|ACE2 308 ----FKEAEKFFVSVGLPNM-TQGFWENSMLT---------------------DPGNVQKAVCHPTAWDL--GKG----D 355 (805)
2373 Q Consensus 308 ----fkeaekffvsvglpnm-tqgfwensmlt---------------------dpgnvqkavchptawdl--gkg----d 355 (805)
2374 ++-++++| .+++... ...+|..+... .||.-..+.|.+...+. ..| .
2375 T Consensus 367 ~~~l~~~~~~~f-g~~~~~~~~~~~W~~~v~~~~v~~~~~~~~~g~~ylD~~~r~~K~~~~~~~~~~~~~~~~~g~~~~p 445 (678)
2376 T 2O3E_A 367 TEGLLSIYQELL-GLSFEQVPDAHVWNKSVSLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMS 445 (678)
2377 T ss_dssp HHHHHHHHHHHH-TEEEEECTTCCCSSTTCEEEEEEETTTCCEEEEEEEECSCCTTSCCSCEEEEEECCBBCTTSCBCCE
2378 T ss_pred HHHHHHHHHHHh-CCEEEECCCCCCccCCCeEEEEEECCCCcEEEEEEEECCCCCCCCCCcceeeecCCccCCCCCeeCe
2379 Confidence 34444444 4444332 23457665541 23332233343322211 111 3
2380
2381
2382 Q sp|Q9BYF1|ACE2 356 FRILMCTKV----------TMDDFLTAHHEMGHIQYDMAYAA-QPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLL 424 (805)
2383 Q Consensus 356 frilmctkv----------tmddfltahhemghiqydmayaa-qpfllrnganegfheavgeimslsaatpkhlksigll 424 (805)
2384 +++++|... +.+|+.|.+||+||..+.+.... +|.+...+...+|+|+.+.+|...+..|.+|+.++..
2385 T Consensus 446 ~~~i~~n~~~~~~~~~~ll~~~~~~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~l~E~~~~~~~~L~~l~~~ 525 (678)
2386 T 2O3E_A 446 VAALVVNFSQPVAGRPSLLRHDEVETYFHEFGHVMHQICAQTDFARFSGTNVERDFVEVPSQMLENWVWDVDSLRKLSKH 525 (678)
2387 T ss_dssp EEEEECCCCCCBTTBCCBCCHHHHHHHHHHHHHHHHHHHCCBSSGGGSTTCSCTTTTTHHHHHHHGGGGCHHHHHHHCCC
2388 T ss_pred EEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhcCCcHHHcCCcccchhhchhHHHhHHhhcCHHHHHHHhcc
2389 Confidence 567877653 89999999999999999877652 3333333467899999999999999999999999876
2390
2391
2392 Q sp|Q9BYF1|ACE2 425 SPDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
2393 Q Consensus 425 spdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
2394 ..+-+.-.+..++.+++ +++.++..+++. .++. .++.+.. . ..-+.||++.++..|+ |++.+ .+.
2395 T Consensus 526 ~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~l~~a-~~d~---~l~~~~~-~-~~~~~~~~~~~~~~g~--~~~~~--~~~ 595 (678)
2396 T 2O3E_A 526 YKDGHPITDELLEKLVASRLVNTGLLTLRQIVLS-KVDQ---SLHTNAT-L-DAASEYAKYCTEILGV--AATPG--TNM 595 (678)
2397 T ss_dssp SSSCCCCCHHHHHHHHHTTTTTHHHHHHHHHHHH-HHHH---HHTTCTT-S-CHHHHHHHHCCCCCSS--CCCTT--CCG
2398 T ss_pred CCCCCCCCHHHHHHHHHhhhhhHHHHHHHHHHHH-HHHH---HHhcCCC-c-cHHHHHHHHHHHHHCC--CCCCC--CCC
2399 Confidence 65544445667888888 788888888776 4454 3455542 2 2357888877777786 43322 456
2400
2401
2402 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSF--IRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFN-MLRLGKSEPWTLALENVVGA 576 (805)
2403 Q Consensus 500 paslfhvsndysf--iryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfn-mlrlgksepwtlalenvvga 576 (805)
2404 +.+..|..++|.+ ..|........++-+++|+. .||+ +.++|+++.+ +|..|.+.||.-.++.+.|.
2405 T Consensus 596 ~~~~~hl~~~y~~~Yy~Yl~s~vla~~i~~~~~~~---~~~~-------~~~~g~~~~~~~l~~G~s~~~~e~l~~~~g~ 665 (678)
2406 T 2O3E_A 596 PATFGHLAGGYDGQYYGYLWSEVFSMDMFHSCFKK---EGIM-------NPEVGMKYRNLILKPGGSLDGMDMLQNFLQR 665 (678)
2407 T ss_dssp GGGCTTSSSSCTTCTTHHHHHHHHHHHHCCCCCCH---HCTT-------CHHHHHHHCCCCCTTGGGSCHHHHHHHHHTS
2408 T ss_pred cccHHHHHccchHHHHHHHHHHHHHHHHHHHHHHh---cCCC-------CHHHHHHHHHHhcccCCCCCHHHHHHHHhCC
2409 Confidence 7888898776644 23333333444444443321 2333 3589999998 99999999999999999995
2410
2411
2412 Q sp|Q9BYF1|ACE2 577 KNMNVRPLLNYF 588 (805)
2413 Q Consensus 577 knmnvrpllnyf 588 (805)
2414 .+++.+++.|+
2415 T Consensus 666 -~~~~~~ll~~~ 676 (678)
2416 T 2O3E_A 666 -EPNQKAFLMSR 676 (678)
2417 T ss_dssp -CCCSHHHHHHH
2418 T ss_pred -CCCHHHHHHHc
2419 Confidence 79999988875
2420
2421
2422 No 28
2423 >5LV0_A Neurolysin, mitochondrial (E.C.3.4.24.16), GLY-VAL-VAL amyloid; PROTEASE, MITOCHONDRIA, HYDROLASE, amyloid-beta; 2.7A {Homo sapiens}
2424 Probab=99.89 E-value=6.2e-28 Score=240.22 Aligned_cols=504 Identities=15% Similarity=0.198 Sum_probs=338.6 Template_Neff=9.600
2425
2426 Q sp|Q9BYF1|ACE2 41 YQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP-------------LQEIQNLTVKLQLQALQQNGSSV 107 (805)
2427 Q Consensus 41 yqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp-------------lqeiqnltvklqlqalqqngssv 107 (805)
2428 .....+.|.++++.+++..+..+.+..++++|..+..+-..+|. +.+-+...++..++.++.+|..
2429 T Consensus 83 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~l~~e~~~~l~~~l~~~~~~G~~- 161 (686)
2430 T 5LV0_A 83 VERTMLDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIVHLQETCDLGKIKPEARRYLEKSIKMGKRNGLH- 161 (686)
2431 T ss_dssp HHHHHHHSHHHHCSCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHHHHSCTTTSCHHHHHHHHHHHHHHHHTTTT-
2432 T ss_pred hHHHHhhhHHhhCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHHhccchhcCCHHHHHHHHHHHHHHHHcCCC-
2433 Confidence 44556788899998888888888899999999888765455553 2233334456666777888876
2434
2435
2436 Q sp|Q9BYF1|ACE2 108 LSEDKSKRLNTI---LNTMSTIYSTGKVCNPD-------------------------NPQECLLL-EPGLNEIMANSLDY 158 (805)
2437 Q Consensus 108 lsedkskrlnti---lntmstiystgkvcnpd-------------------------npqeclll-epglneimansldy 158 (805)
2438 |++++.+++..+ +..+++.|+....|... ++ .++-+ .|.+..+|+++-|.
2439 T Consensus 162 L~~~~~~~~~~l~~~~~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~~-~~~~l~~~~~~~~l~~~~d~ 240 (686)
2440 T 5LV0_A 162 LPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDDK-YKITLKYPHYFPVMKKCCIP 240 (686)
2441 T ss_dssp SCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECTTTTTTCCHHHHHHSCBCTTSC-EEEESSHHHHHHHHHHCCCH
2442 T ss_pred CCHHHHHHHHHHHHHHHHHHHHHHHccCCCCceeeCCHHHHcCCCHHHHHHHhccCCCC-eEEEcCCccHHHHHHhCCCH
2443 Confidence 455555666665 66667777776665421 11 23333 46788899999999
2444
2445
2446 Q sp|Q9BYF1|ACE2 159 NERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYE 238 (805)
2447 Q Consensus 159 nerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplye 238 (805)
2448 ..|-.+|+.|....++...+++++.+.+++++|+...|.+|.+||...+.+. +...+.+-++...+.++|+++
2449 T Consensus 241 ~~R~~~~~a~~~~~~~~n~~~l~~ll~lR~~~A~~lG~~s~~~~~l~~~~~~-------~~~~v~~~l~~l~~~~~p~~~ 313 (686)
2450 T 5LV0_A 241 ETRRRMEMAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAK-------STSRVTAFLDDLSQKLKPLGE 313 (686)
2451 T ss_dssp HHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSTTC-------SHHHHHHHHHHHHHHHHHHHH
2452 T ss_pred HHHHHHHHHHhcCCchhHHHHHHHHHHHHHHHHHHhCCCCHHHHHhhccCCC-------CHHHHHHHHHHHHHHhHHHHH
2453 Confidence 9999999999887666888999999999999999999999999998776543 233444445556678899999
2454
2455
2456 Q sp|Q9BYF1|ACE2 239 HLHAYVRAKLMNAYPSYISP-IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVS 317 (805)
2457 Q Consensus 239 hlhayvraklmnaypsyisp-igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvs 317 (805)
2458 .+++++++......+.+-.+ .+.+ ..|...|-+.... +..++++++.+.+.+....+++.+..++-+
2459 T Consensus 314 ~~~~~l~~~~~~~~~~~g~~~~~~l----------~~wD~~~~~~~~~--~~~~~~~~~~~~~yf~~~~v~~~~~~~~~~ 381 (686)
2460 T 5LV0_A 314 AEREFILNLKKKECKDRGFEYDGKI----------NAWDLYYYMTQTE--ELKYSIDQEFLKEYFPIEVVTEGLLNTYQE 381 (686)
2461 T ss_dssp HHHHHHHHHHHHHHHHHTCCCCSSC----------BTTTHHHHHHHHH--HHHHCCCHHHHGGGCBHHHHHHHHHHHHHH
2462 T ss_pred HHHHHHHHHHHHHchhCCCCcCCCC----------ChhhHHHHHHHHH--HHhcCCCHHHHHhhCCHHHHHHHHHHHHHH
2463 Confidence 99999976444322111001 1111 2344444443332 235667777777777777777777777666
2464
2465
2466 Q sp|Q9BYF1|ACE2 318 -VGLPNM---TQGFWENSML---------------------TDPGNVQKAVCHPTAWDLGKG-----DFR-----ILMC- 361 (805)
2467 Q Consensus 318 -vglpnm---tqgfwensml---------------------tdpgnvqkavchptawdlgkg-----dfr-----ilmc- 361 (805)
2468 .|+.-. ...+|.++.. ..+|.-..+.|.+ +..+ +.+ +++|
2469 T Consensus 382 lfg~~~~~~~~~~~w~~~v~~~~v~~~~~~~~lg~~~lD~~~r~~K~~~a~~~~----~~~~~~~~~~~~~~p~~~i~~n 457 (686)
2470 T 5LV0_A 382 LLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFG----LQPGCLLPDGSRMMAVAALVVN 457 (686)
2471 T ss_dssp HHTEEEEEETTCCCSSTTCEEEEEEETTTCCEEEEEEEECSCCTTSCCSCEEEE----EECCCBCTTSSBCCEEEEEECC
2472 T ss_pred HHCcEEEECCCCCccCCCceEEEEEECCCCcEEEEEEEECCCCCCCCCCcceee----eeCCccCCCCCeeCeEEEEEec
2473 Confidence 665433 2335665533 1234333344443 3222 122 4554
2474
2475
2476 Q sp|Q9BYF1|ACE2 362 ---------TKVTMDDFLTAHHEMGHIQYDMAYAA-QPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQED 431 (805)
2477 Q Consensus 362 ---------tkvtmddfltahhemghiqydmayaa-qpfllrnganegfheavgeimslsaatpkhlksigllspdfqed 431 (805)
2478 +.++++|+.|.+||+||..+.+.+.. +|.+...+....|+|+.+.+|..-+..|++|+.++....+-+.-
2479 T Consensus 458 ~~~~~~~~~~~l~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~L~~l~~~~~~~~~~ 537 (686)
2480 T 5LV0_A 458 FSQPVAGRPSLLRHDEVRTYFHQFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPI 537 (686)
2481 T ss_dssp CCCCBTTBCCBCCHHHHHHHHHHHHHHHHHHHCCCSSSTTSTTCSCTTTTTHHHHHHHGGGGCHHHHHHHCCCTTTCCCC
2482 T ss_pred CCCCCCCCCCCCChHHHHHHHHHHHHHHHHHHhcCCcHHHcCCCccchhchHhHHHhHHhhcCHHHHHHHhhhcCCCCCC
2483 Confidence 56699999999999999999987764 56666667889999999999999999999999988665544333
2484
2485
2486 Q sp|Q9BYF1|ACE2 432 NETEINFLLKQ-----ALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHV 506 (805)
2487 Q Consensus 432 neteinfllkq-----altivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycdpaslfhv 506 (805)
2488 .+..++.+++. ++.++..+++. +++. .++.+.. ....+.|+++.++..|+ |.+. ....+.+..|.
2489 T Consensus 538 ~~~~~~~l~~~~~~~~~~~~~~~l~~~-~~d~---~l~~~~~--~~~~~~~~~~~~~~~g~--~~~~--~~~~~~~~~hl 607 (686)
2490 T 5LV0_A 538 ADDLLEKLVASRLVNTGLLTLRQIVLS-KVDQ---SLHTNTS--LDAASEYAKYCSEILGV--AATP--GTNMPATFGHL 607 (686)
2491 T ss_dssp CHHHHHHHHHGGGTTHHHHHHHHHHHH-HHHH---HHTTCCS--SCHHHHHHHHCCCCCCS--BCCT--TCCSGGGCGGG
2492 T ss_pred CHHHHHHHHHhhhHhHHHHHHHHHHHH-HHHH---HHhcCCC--ccHHHHHHHHHHHHhCC--CCCC--CCCCccccHHH
2493 Confidence 45667777776 67777777655 5664 3455542 23578899987887785 3322 23567777888
2494
2495
2496 Q sp|Q9BYF1|ACE2 507 SNDYSFIRYYTRTLYQFQFQEALC-QAAKHEGPLHKCDISNSTEAGQKLFN-MLRLGKSEPWTLALENVVGAKNMNVRPL 584 (805)
2497 Q Consensus 507 sndysfiryytrtlyqfqfqealc-qaakhegplhkcdisnsteagqklfn-mlrlgksepwtlalenvvgaknmnvrpl 584 (805)
2498 ..+|.. .||.. ++..-+...+. +..+..||+ +.++|.++.+ +|..|.+.+|.-.++.+.|. .++..++
2499 T Consensus 608 ~~~y~~-~yY~Y-l~s~~~A~~i~~~~f~~~~~~-------~~~~g~~~~~~~L~~G~s~~~~e~l~~~~G~-~~~~~~l 677 (686)
2500 T 5LV0_A 608 AGGYDG-QYYGY-LWSEVFSMDMFYSCFKKEGIM-------NPEVGMKYRNLILKPGGSLDGMDMLHNFLKR-EPNQKAF 677 (686)
2501 T ss_dssp TTTCTT-CTTHH-HHHHHHHHHHCCCCCTTSCTT-------CHHHHHHHCCCCCTTTTSSCHHHHHHHHHSS-CCCSHHH
2502 T ss_pred Hccchh-HHHHH-HHHHHHHHHHHHHHHHhcCCC-------CHHHHHHHHHHhhhcCCCCCHHHHHHHHhCC-CCCHHHH
2503 Confidence 766653 44421 22211111111 112222332 3689999999 99999999999999999994 7999999
2504
2505
2506 Q sp|Q9BYF1|ACE2 585 LNYFE 589 (805)
2507 Q Consensus 585 lnyfe 589 (805)
2508 +.++.
2509 T Consensus 678 l~~~~ 682 (686)
2510 T 5LV0_A 678 LMSRG 682 (686)
2511 T ss_dssp HHHHT
2512 T ss_pred HHHcC
2513 Confidence 88864
2514
2515
2516 No 29
2517 >1S4B_P Thimet oligopeptidase (E.C.3.4.24.15); Zinc metallopeptidase domain, HYDROLASE; 2.0A {Homo sapiens} SCOP: d.92.1.5
2518 Probab=99.88 E-value=1.6e-27 Score=236.83 Aligned_cols=516 Identities=16% Similarity=0.187 Sum_probs=326.3 Template_Neff=9.600
2519
2520 Q sp|Q9BYF1|ACE2 26 KTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPL-------------QEIQNLT 92 (805)
2521 Q Consensus 26 ktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmypl-------------qeiqnlt 92 (805)
2522 +..+..+......+-...+.+.|.++++.+++..+....+-.++++|..+..+-...|.+ .+.+...
2523 T Consensus 47 ~~~i~~~d~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~ld~e~~r~ 126 (674)
2524 T 1S4B_P 47 ESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 126 (674)
2525 T ss_pred HHhHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHcCCHHHHHHHHHHHhCcchhhCCHHHHHH
2526 Confidence 344556666666677888899999999999999999999999999999887666666652 2222333
2527
2528
2529 Q sp|Q9BYF1|ACE2 93 VKLQLQALQQNGSSVLSEDKSKRLNTIL---NTMSTIYSTGKVCNPDN------------------------PQECLLLE 145 (805)
2530 Q Consensus 93 vklqlqalqqngssvlsedkskrlntil---ntmstiystgkvcnpdn------------------------pqecllle 145 (805)
2531 ++..+..++.+|.. |++++.+++..+. ..++..|.....|.... ...++.+.
2532 T Consensus 127 l~~~l~~~~~~G~~-L~~~~~~~~~~l~~~i~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~~~~~~l~ 205 (674)
2533 T 1S4B_P 127 LERLIKLGRRNGLH-LPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLK 205 (674)
2534 T ss_pred HHHHHHHHHHcCCC-CCHHHHHHHHHHHHHHHHHHHHHHHhccccccccEEeHHHHcCCCHHHHHHHHHHHcCCeEEEcC
2535 Confidence 45555666777754 6666656665554 44677777777665321 11234444
2536
2537
2538 Q sp|Q9BYF1|ACE2 146 -PGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIE 224 (805)
2539 Q Consensus 146 -pglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqlie 224 (805)
2540 |.+..+|+++-|...|-.+|+.|+...++...+++++.+.+++++|+...|.+|.+||..++.+. +..++.+
2541 T Consensus 206 ~~~~~~il~~~~d~~~R~~~~~a~~~~~~~~~~~~l~~l~~lR~~~A~~lGy~s~~~~~l~~~~~~-------~~~~v~~ 278 (674)
2542 T 1S4B_P 206 YPHYFPLLKKCHVPETRRKVEEAFNSRCKEENSAILKELVTLRAQKSRLLGFHTHADYVLEMNMAK-------TSQTVAT 278 (674)
2543 T ss_pred CccHHHHHhcCCCHHHHHHHHHHHHccCCcccHHHHHHHHHHHHHHHHHhCCCCHHHHHccccCCC-------CHHHHHH
2544 Confidence 67899999999999999999999987777889999999999999999999999999998765442 2223333
2545
2546
2547 Q sp|Q9BYF1|ACE2 225 DVEHTFEEIKPLYEHLHAYVRAKLM---NAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQA 301 (805)
2548 Q Consensus 225 dvehtfeeikplyehlhayvraklm---naypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqa 301 (805)
2549 -.+...+.++|+|+..+++++.... +.+.. +..+-+ ..|...|-...+... ...+..+.+...
2550 T Consensus 279 ~l~~l~~~~~p~~~~~~~~l~~~~~~~~~~~g~--~~~~~l----------~~wD~~y~~~~~~~~--~~~~~~~~i~~y 344 (674)
2551 T 1S4B_P 279 FLDELAQKLKPLGEQERAVILELKRAECERRGL--PFDGRI----------RAWDMRYYMNQVEET--RYCVDQNLLKEY 344 (674)
2552 T ss_pred HHHHHHHHhHHHHHHHHHHHHHHHHHHHHhcCC--CCCCCC----------ChhcHHHHHHHHHHh--cCCCCHHHHHhh
2553 Confidence 3445567889999999888775322 22210 001111 234444444333211 223333333332
2554
2555
2556 Q sp|Q9BYF1|ACE2 302 WD----AQRIFKEAEKFFVSVGLPN---MTQGFWENSML-----------------TD----PGNVQKAVCHPTAWDL-- 351 (805)
2557 Q Consensus 302 wd----aqrifkeaekffvsvglpn---mtqgfwensml-----------------td----pgnvqkavchptawdl-- 351 (805)
2558 .. ...+++.++++| |+.. ....+|.++.. .| ||.-..+.|.+...+.
2559 T Consensus 345 f~~~~~~~~l~~~~~~~f---g~~~~~~~~~~~W~~~v~~~~v~d~~~~~~lg~~~lD~~~r~~K~~~a~~~~~~~~~~~ 421 (674)
2560 T 1S4B_P 345 FPVQVVTHGLLGIYQELL---GLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLR 421 (674)
2561 T ss_pred CCHHHHHHHHHHHHHHHh---CCEEEECCCCCcccCCceEEEEEeCCCCcEEEEEEEECCCCCCCCCCcceeeEecCccC
2562 Confidence 21 245666666666 4322 24456777654 22 2222234444332211
2563
2564
2565 Q sp|Q9BYF1|ACE2 352 --GKGD--FRIL----------MCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGAN--EGFHEAVGEIMSLSAATP 415 (805)
2566 Q Consensus 352 --gkgd--fril----------mctkvtmddfltahhemghiqydmayaaqpfllrngan--egfheavgeimslsaatp 415 (805)
2567 |+.. ..++ .|+.++.+|+.|.+||+||..+.+.+..++. ...|++ -.|+|+.+.+|...+..|
2568 T Consensus 422 ~~~~~~~p~~~l~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~-~~~g~~~~~d~~E~~S~~~E~~~~~~ 500 (674)
2569 T 1S4B_P 422 QDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFA-MFSGTHVERDFVEAPSQMLENWVWEQ 500 (674)
2570 T ss_pred CCCCeeccEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhCCCch-hhcCCCCCCcccccchHHHHHhhcCH
2571 Confidence 1000 0122 6778889999999999999999998876544 456655 799999999999999999
2572
2573
2574 Q sp|Q9BYF1|ACE2 416 KHLKSIGLLSPDFQEDNETEINFLLKQA-----LTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEP 490 (805)
2575 Q Consensus 416 khlksigllspdfqedneteinfllkqa-----ltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvep 490 (805)
2576 ++|+.++.-..+-+.-.+..++.+++.. +.++..+.+ ..++.+ ++.+. ..++.+.||++..+..|+ |
2577 T Consensus 501 ~~L~~l~~~~~~~~~l~~~~~~~l~~~~~~~~~l~~~~~l~~-~~~d~~---l~~~~--~~~~~~~~~~l~~~~~g~--~ 572 (674)
2578 T 1S4B_P 501 EPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVL-AKVDQA---LHTQT--DADPAEEYARLCQEILGV--P 572 (674)
2579 T ss_pred HHHHHHhhccCCCCCCCHHHHHHHHHhhcHHHHHHHHHHHHH-HHHHHH---HhcCC--CCcHHHHHHHHHHHHcCC--C
2580 Confidence 9999887543221111233455554322 222222222 222322 23222 256788899999998887 3
2581
2582
2583 Q sp|Q9BYF1|ACE2 491 VPHDETYCDPASLFHVSNDYSF--IRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWT 567 (805)
2584 Q Consensus 491 vphdetycdpaslfhvsndysf--iryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwt 567 (805)
2585 .+.+ ...+.+..|...+|.+ ..|....+..+++-.+.| +..||+ +.++|.++. ++|..|.+.+|.
2586 T Consensus 573 ~~~~--~~~~~~~~h~~~~y~~~yysYl~s~v~A~~i~~~~~---~~~~~~-------~~~~g~~~~~~~L~~G~s~~~~ 640 (674)
2587 T 1S4B_P 573 ATPG--TNMPATFGHLAGGYDAQYYGYLWSEVYSMDMFHTRF---KQEGVL-------NSKVGMDYRSCILRPGGSEDAS 640 (674)
2588 T ss_pred CCCC--CCchhhhHHHHccchHHHHHHHHHHHHHHHHHHHHH---hhhCCC-------CHHHHHHHHHHhcccCCCCCHH
2589 Confidence 3222 3466778888755544 333333333444322222 223443 358899998 899999999999
2590
2591
2592 Q sp|Q9BYF1|ACE2 568 LALENVVGAKNMNVRPLLNYF 588 (805)
2593 Q Consensus 568 lalenvvgaknmnvrpllnyf 588 (805)
2594 -.++++.| .+++..+++.++
2595 T Consensus 641 e~l~~~lG-~~~~~~~~l~~~ 660 (674)
2596 T 1S4B_P 641 AMLRRFLG-RDPKQDAFLLSK 660 (674)
2597 T ss_pred HHHHHHhC-CCCCHHHHHHHc
2598 Confidence 99999988 568888887665
2599
2600
2601 No 30
2602 >5L44_A K-26 dipeptidyl carboxypeptidase; dipeptidyl carboxypeptidase, metalloprotease, K-26 tripeptide; HET: K26, SO4; 1.75A {Astrosporangium hypotensionis K-26}
2603 Probab=99.77 E-value=4.9e-23 Score=205.45 Aligned_cols=512 Identities=16% Similarity=0.122 Sum_probs=318.9 Template_Neff=9.600
2604
2605 Q sp|Q9BYF1|ACE2 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP---------LQEIQNLTVKLQLQ 98 (805)
2606 Q Consensus 28 fldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp---------lqeiqnltvklqlq 98 (805)
2607 ++..+..-...+..-.+++++.+.++.+++..+..+.+..+.+.+..+.......|. +.+-+...++..++
2608 T Consensus 76 ~i~~le~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~l~~e~~~~l~~~l~ 155 (683)
2609 T 5L44_A 76 TVAALERSGQVLTRVSAVFFNQSSSDTNPTVQEIQKQIIPKLTQHGDAIHLNRPLFARIKQISPDGLDAEQAWLLERYVT 155 (683)
2610 T ss_dssp CCCHHHHCCHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHTCCCTTCCHHHHHHHHHHHH
2611 T ss_pred HHHHHHHhhHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHcccCCCHHHHHHHHHHHH
2612 Confidence 344444444555556778888888887888888888888888888766655444443 22223445556677
2613
2614
2615 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSED--KSKRLNTILNTMSTIYS----TGK----VCN---------PDN--------------PQ-ECLLL 144 (805)
2616 Q Consensus 99 alqqngssvlsed--kskrlntilntmstiys----tgk----vcn---------pdn--------------pq-eclll 144 (805)
2617 .+.++|...++++ +-..++..+..++..|+ +.+ +|- |.. +. .++-+
2618 T Consensus 156 ~~~~~G~~l~~~~~e~~~~l~~~~~~l~~~f~~n~~~~~~~~~~~~~~~~~l~glp~~~~~~~~~~~~~~~~~G~~~i~l 235 (683)
2619 T 5L44_A 156 DFVRAGAELGAGDQERLKALNEELSTLSTRFEQNLLAHTNASAVIVDDVAQLDGLSDDSVKAAAETAKSRGLPGKYVIPL 235 (683)
2620 T ss_dssp HHHHTTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCEEESCGGGGTTSCHHHHHHHHHHHHHTTCTTSEEECC
2621 T ss_pred HHHHhcccCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccceecCCHHHHCCCCHHHHHHHHHHHHHcCCCCCeEEec
2622 Confidence 7888888877765 34445666777778887 332 332 110 11 23444
2623
2624
2625 Q sp|Q9BYF1|ACE2 145 E-PGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLI 223 (805)
2626 Q Consensus 145 e-pglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqli 223 (805)
2627 . |....+|.++-|...|-.+|++|.....+...+++++.+-+++++|+...|++|.+||-.++.+...
2628 T Consensus 236 ~~~~~~~il~~~~d~~~Rk~~~~a~~~~~~~~n~~~l~~lv~~R~~~A~~lGy~s~a~~~l~~~~~~~~----------- 304 (683)
2629 T 5L44_A 236 VLPTGQPGLAELTDRALRERIHRASIQRGVPDNEELIVRIATLRAERAKLLGYPTHAAYVVADQTAPTT----------- 304 (683)
2630 T ss_dssp CSSSSCGGGGTCCCHHHHHHHHHHHHTTTTTTTHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSSSCCH-----------
2631 T ss_pred CCCchHHHHHhCCCHHHHHHHHHHHHhcCCcchHHHHHHHHHHHHHHHHHhCCCCHHHHHcCCCCCCCH-----------
2632 Confidence 4 6788899999999999999999997655678899999999999999999999999999877665421
2633
2634
2635 Q sp|Q9BYF1|ACE2 224 EDVEHTFEE-IKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAW 302 (805)
2636 Q Consensus 224 edvehtfee-ikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqaw 302 (805)
2637 ++|.....+ +++++..+|++++.+... + |+ --..|.-.|-....... .+.+..+.+..-.
2638 T Consensus 305 ~~v~~~L~~l~~~~~p~~~~~~~~l~~~-~---------------~~-~l~~wD~~y~~~~~~~~--~~~~~~~~~~~yf 365 (683)
2639 T 5L44_A 305 EAVTEMLGKLTPPAVANAHREADELREQ-A---------------GH-DLEPWDWSFYAEKVLKE--RYAIDGRQMRPYF 365 (683)
2640 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHH-H---------------SS-CCCGGGHHHHHHHHHHH--HHCCCHHHHGGGC
2641 T ss_pred HHHHHHHHHhhHHhHHHHHHHHHHHHHH-c---------------CC-CCCccCHHHHHHHHHHH--hhCCChhHhHhhc
2642 Confidence 223222222 346666778887754321 1 11 01223332322211111 1111111111111
2643
2644
2645 Q sp|Q9BYF1|ACE2 303 DAQ-----RIFKEAEKFF--------------------VSVGL-PNMTQGFWENSMLTDPGNVQKAVCHPTAWD--LGKG 354 (805)
2646 Q Consensus 303 daq-----rifkeaekff--------------------vsvgl-pnmtqgfwensmltdpgnvqkavchptawd--lgkg 354 (805)
2647 ... .+|.-++++| .-.+- ......+|-. ....+|....+.|++..-. ....
2648 T Consensus 366 ~~~~v~~~~l~~~~~~lfg~~~~~~~~~~~w~~~v~~~~v~~~~~~~lg~~~lD-~~~r~~K~~~~~~~~~~~~~~~~~~ 444 (683)
2649 T 5L44_A 366 ELDRVLRDGVFHAATLLYGITFTERPDLVGYHPDVRVFEVFNEDGSQLGLFLGD-YYARPSKRGGAWMNSLVKQSTLEGT 444 (683)
2650 T ss_dssp BHHHHCCCCCCHHHHHHHCCEEEECTTSCCSSTTCEEEEEECTTSCEEEEEEEE-EECCTTSCSSCEEEEEECCBTTTTB
2651 T ss_pred CHHHHHHHHHHHHHHHHhCCEEEECCCCCCccCCeEEEEEEcCCCCEEEEEEEe-ccCCCCCCCCccccccccccccCCC
2652 Confidence 111 1222222221 00000 0111113322 1223344444566653210 0134
2653
2654
2655 Q sp|Q9BYF1|ACE2 355 DFRILMCTK-----------VTMDDFLTAHHEMGHIQYDMAYA-AQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIG 422 (805)
2656 Q Consensus 355 dfrilmctk-----------vtmddfltahhemghiqydmaya-aqpfllrnganegfheavgeimslsaatpkhlksig 422 (805)
2657 ...|.+|.. .+.+|+.|.+||+||..+.+... .+|.+.+.+....|.|+.+.+|.+-+..|.+|++++
2658 T Consensus 445 ~p~v~l~~~~~~~~~~~~~l~~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~L~~~~ 524 (683)
2659 T 5L44_A 445 RPVVVNNLNIAKPPAGEPTLMTFEEVNTMFHEFGHALHGLFSEVHYPRFSGTAVPRDFVEYPSQVNEMWAVWPSVLANYA 524 (683)
2660 T ss_dssp CCEEEEEEEECCCCTTCCCBCCHHHHHHHHHHHHHHHHHHTCCCSSGGGCTTCSCHHHHHHHHHHHTHHHHCHHHHHHHC
2661 T ss_pred CCEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHcCCCCccccCCCCCchhhccchHHhHhhhcCHHHHHHHh
2662 Confidence 577888887 89999999999999999988765 577777777889999999999999999999999987
2663
2664
2665 Q sp|Q9BYF1|ACE2 423 LLSPDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
2666 Q Consensus 423 llspdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
2667 ....+-+.-.+..++.++. +++.++..+++. .++.+ ++.+..+.+.+..-||+...+. |+.-|... . .
2668 T Consensus 525 ~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~l~~a-~~D~~---lh~~~~~~~~~~~~~~~~~~~~-g~~~~~~~-~-~ 597 (683)
2669 T 5L44_A 525 RHWQTGDPMPKDLLDRMLKSQKYNQGYKTVEYLAAT-LLDWS---WHTFQTPPENALTFEHEALTTA-GVDLKLVP-P-R 597 (683)
2670 T ss_dssp BCTTTCCBCCHHHHHHHHHTTSTTHHHHHHHHHHHH-HHHHH---HTSCSSCCSCHHHHHHHHHHHT-TCCBTTBC-C-S
2671 T ss_pred hccCCCCCCCHHHHHHHHHhhchhHHHHHHHHHHHH-HHHHH---HhcCCCCCccHHHHHHHHHHHh-CCCCCCCC-C-c
2672 Confidence 6643222224455666654 567777777775 66655 3444444466777788866665 76544321 1 2
2673
2674
2675 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSN-DYS--FIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLALENV 573 (805)
2676 Q Consensus 498 cdpaslfhvsn-dys--firyytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwtlalenv 573 (805)
2677 ..+.+..|+.. +|. +..|....+..++.-+++|++ ||+ +.++|+++. .+|+.|.+.||.-.++..
2678 T Consensus 598 ~~~~~~~hi~~~~y~~~yy~Yl~s~v~a~~i~~~f~~~----~~~-------~~~~g~~~r~~iL~~G~s~~~~e~l~~f 666 (683)
2679 T 5L44_A 598 YRSTYFAHIWSSGYSAGYYSYIWSEVLDADTVDWFHEN----GGL-------LRENGDTFRQKLLSKGGSVDPMTAFQSF 666 (683)
2680 T ss_dssp SCGGGCHHHHTSSCTTCTTHHHHHHHHHHHHHHHHHHT----TSS-------CHHHHHHHCCCCCTCTTSSCHHHHHHHH
2681 T ss_pred ccccccHhHhcCCchHHHHHHHHHHHHHHHHHHHHHHc----CCC-------cHHHHHHHHHHHHHcCCCCCHHHHHHHH
2682 Confidence 23677777654 443 335555555666666665543 444 358899999 999999999999999999
2683
2684
2685 Q sp|Q9BYF1|ACE2 574 VGAKNMNVRPLLNYFE 589 (805)
2686 Q Consensus 574 vgaknmnvrpllnyfe 589 (805)
2687 .|.. .+..+++.|+.
2688 T Consensus 667 ~G~~-~s~~~~l~~~~ 681 (683)
2689 T 5L44_A 667 RGRT-PRIEPLLDRRG 681 (683)
2690 T ss_dssp HSSS-CCSHHHHHHHT
2691 T ss_pred hCCC-CChHHHHHHcC
2692 Confidence 9986 88888888764
2693
2694
2695 No 31
2696 >5L43_B K-26 dipeptidyl carboxypeptidase; dipeptidyl carboxypeptidase, metalloprotease, K-26 tripeptide; HET: SO4; 1.8A {Astrosporangium hypotensionis K-26}
2697 Probab=99.77 E-value=4.9e-23 Score=205.45 Aligned_cols=512 Identities=16% Similarity=0.122 Sum_probs=318.9 Template_Neff=9.600
2698
2699 Q sp|Q9BYF1|ACE2 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP---------LQEIQNLTVKLQLQ 98 (805)
2700 Q Consensus 28 fldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp---------lqeiqnltvklqlq 98 (805)
2701 ++..+..-...+..-.+++++.+.++.+++..+..+.+..+.+.+..+.......|. +.+-+...++..++
2702 T Consensus 76 ~i~~le~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~l~~e~~~~l~~~l~ 155 (683)
2703 T 5L43_B 76 TVAALERSGQVLTRVSAVFFNQSSSDTNPTVQEIQKQIIPKLTQHGDAIHLNRPLFARIKQISPDGLDAEQAWLLERYVT 155 (683)
2704 T ss_dssp CCCHHHHCCHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHTCCSTTCCHHHHHHHHHHHH
2705 T ss_pred HHHHHHHhhHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHcccCCCHHHHHHHHHHHH
2706 Confidence 344444444555556778888888887888888888888888888766655444443 22223445556677
2707
2708
2709 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSED--KSKRLNTILNTMSTIYS----TGK----VCN---------PDN--------------PQ-ECLLL 144 (805)
2710 Q Consensus 99 alqqngssvlsed--kskrlntilntmstiys----tgk----vcn---------pdn--------------pq-eclll 144 (805)
2711 .+.++|...++++ +-..++..+..++..|+ +.+ +|- |.. +. .++-+
2712 T Consensus 156 ~~~~~G~~l~~~~~e~~~~l~~~~~~l~~~f~~n~~~~~~~~~~~~~~~~~l~glp~~~~~~~~~~~~~~~~~G~~~i~l 235 (683)
2713 T 5L43_B 156 DFVRAGAELGAGDQERLKALNEELSTLSTRFEQNLLAHTNASAVIVDDVAQLDGLSDDSVKAAAETAKSRGLPGKYVIPL 235 (683)
2714 T ss_dssp HHHHTTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCEEESCGGGGTTSCHHHHHHHHHHHHHTTCTTSEEECC
2715 T ss_pred HHHHhcccCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccceecCCHHHHCCCCHHHHHHHHHHHHHcCCCCCeEEec
2716 Confidence 7888888877765 34445666777778887 332 332 110 11 23444
2717
2718
2719 Q sp|Q9BYF1|ACE2 145 E-PGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLI 223 (805)
2720 Q Consensus 145 e-pglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqli 223 (805)
2721 . |....+|.++-|...|-.+|++|.....+...+++++.+-+++++|+...|++|.+||-.++.+...
2722 T Consensus 236 ~~~~~~~il~~~~d~~~Rk~~~~a~~~~~~~~n~~~l~~lv~~R~~~A~~lGy~s~a~~~l~~~~~~~~----------- 304 (683)
2723 T 5L43_B 236 VLPTGQPGLAELTDRALRERIHRASIQRGVPDNEELIVRIATLRAERAKLLGYPTHAAYVVADQTAPTT----------- 304 (683)
2724 T ss_dssp CSSSSCGGGGTCCCHHHHHHHHHHHHTTTTTTTHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSSSCCH-----------
2725 T ss_pred CCCchHHHHHhCCCHHHHHHHHHHHHhcCCcchHHHHHHHHHHHHHHHHHhCCCCHHHHHcCCCCCCCH-----------
2726 Confidence 4 6788899999999999999999997655678899999999999999999999999999877665421
2727
2728
2729 Q sp|Q9BYF1|ACE2 224 EDVEHTFEE-IKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAW 302 (805)
2730 Q Consensus 224 edvehtfee-ikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqaw 302 (805)
2731 ++|.....+ +++++..+|++++.+... + |+ --..|.-.|-....... .+.+..+.+..-.
2732 T Consensus 305 ~~v~~~L~~l~~~~~p~~~~~~~~l~~~-~---------------~~-~l~~wD~~y~~~~~~~~--~~~~~~~~~~~yf 365 (683)
2733 T 5L43_B 305 EAVTEMLGKLTPPAVANAHREADELREQ-A---------------GH-DLEPWDWSFYAEKVLKE--RYAIDGRQMRPYF 365 (683)
2734 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHH-H---------------TS-CCCGGGHHHHHHHHHHH--HHCCCHHHHGGGC
2735 T ss_pred HHHHHHHHHhhHHhHHHHHHHHHHHHHH-c---------------CC-CCCccCHHHHHHHHHHH--hhCCChhHhHhhc
2736 Confidence 223222222 346666778887754321 1 11 01223332322211111 1111111111111
2737
2738
2739 Q sp|Q9BYF1|ACE2 303 DAQ-----RIFKEAEKFF--------------------VSVGL-PNMTQGFWENSMLTDPGNVQKAVCHPTAWD--LGKG 354 (805)
2740 Q Consensus 303 daq-----rifkeaekff--------------------vsvgl-pnmtqgfwensmltdpgnvqkavchptawd--lgkg 354 (805)
2741 ... .+|.-++++| .-.+- ......+|-. ....+|....+.|++..-. ....
2742 T Consensus 366 ~~~~v~~~~l~~~~~~lfg~~~~~~~~~~~w~~~v~~~~v~~~~~~~lg~~~lD-~~~r~~K~~~~~~~~~~~~~~~~~~ 444 (683)
2743 T 5L43_B 366 ELDRVLRDGVFHAATLLYGITFTERPDLVGYHPDVRVFEVFNEDGSQLGLFLGD-YYARPSKRGGAWMNSLVKQSTLEGT 444 (683)
2744 T ss_dssp BHHHHCCCCCHHHHHHHHCCEEEECTTSCCSSTTCEEEEEECTTSCEEEEEEEE-EECCTTSCSSCEEEEEECCBTTTTB
2745 T ss_pred CHHHHHHHHHHHHHHHHhCCEEEECCCCCCccCCeEEEEEEcCCCCEEEEEEEe-ccCCCCCCCCccccccccccccCCC
2746 Confidence 111 1222222221 00000 0111113322 1223344444566653210 0134
2747
2748
2749 Q sp|Q9BYF1|ACE2 355 DFRILMCTK-----------VTMDDFLTAHHEMGHIQYDMAYA-AQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIG 422 (805)
2750 Q Consensus 355 dfrilmctk-----------vtmddfltahhemghiqydmaya-aqpfllrnganegfheavgeimslsaatpkhlksig 422 (805)
2751 ...|.+|.. .+.+|+.|.+||+||..+.+... .+|.+.+.+....|.|+.+.+|.+-+..|.+|++++
2752 T Consensus 445 ~p~v~l~~~~~~~~~~~~~l~~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~L~~~~ 524 (683)
2753 T 5L43_B 445 RPVVVNNLNIAKPPAGEPTLMTFEEVNTMFHEFGHALHGLFSEVHYPRFSGTAVPRDFVEYPSQVNEMWAVWPSVLANYA 524 (683)
2754 T ss_dssp CCEEEEEEEECCCCTTCCCBCCHHHHHHHHHHHHHHHHHHTCCCSSGGGCTTCSCHHHHHHHHHHHTHHHHCHHHHHHHC
2755 T ss_pred CCEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHcCCCCccccCCCCCchhhccchHHhHhhhcCHHHHHHHh
2756 Confidence 577888887 89999999999999999988765 577777777889999999999999999999999987
2757
2758
2759 Q sp|Q9BYF1|ACE2 423 LLSPDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
2760 Q Consensus 423 llspdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
2761 ....+-+.-.+..++.++. +++.++..+++. .++.+ ++.+..+.+.+..-||+...+. |+.-|... . .
2762 T Consensus 525 ~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~l~~a-~~D~~---lh~~~~~~~~~~~~~~~~~~~~-g~~~~~~~-~-~ 597 (683)
2763 T 5L43_B 525 RHWQTGDPMPKDLLDRMLKSQKYNQGYKTVEYLAAT-LLDWS---WHTFQTPPENALTFEHEALTTA-GVDLKLVP-P-R 597 (683)
2764 T ss_dssp BCTTTCCBCCHHHHHHHHHTTSTTHHHHHHHHHHHH-HHHHH---HTTCSSCCSCHHHHHHHHHHHT-TCCBTTBC-C-S
2765 T ss_pred hccCCCCCCCHHHHHHHHHhhchhHHHHHHHHHHHH-HHHHH---HhcCCCCCccHHHHHHHHHHHh-CCCCCCCC-C-c
2766 Confidence 6643222224455666654 567777777775 66655 3444444466777788866665 76544321 1 2
2767
2768
2769 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSN-DYS--FIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLALENV 573 (805)
2770 Q Consensus 498 cdpaslfhvsn-dys--firyytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwtlalenv 573 (805)
2771 ..+.+..|+.. +|. +..|....+..++.-+++|++ ||+ +.++|+++. .+|+.|.+.||.-.++..
2772 T Consensus 598 ~~~~~~~hi~~~~y~~~yy~Yl~s~v~a~~i~~~f~~~----~~~-------~~~~g~~~r~~iL~~G~s~~~~e~l~~f 666 (683)
2773 T 5L43_B 598 YRSTYFAHIWSSGYSAGYYSYIWSEVLDADTVDWFHEN----GGL-------LRENGDTFRQKLLSKGGSVDPMTAFQSF 666 (683)
2774 T ss_dssp SCGGGCHHHHTSSCTTCTTHHHHHHHHHHHHHHHHHHT----TSS-------CHHHHHHHCCCCCTCTTSSCHHHHHHHH
2775 T ss_pred ccccccHhHhcCCchHHHHHHHHHHHHHHHHHHHHHHc----CCC-------cHHHHHHHHHHHHHcCCCCCHHHHHHHH
2776 Confidence 23677777654 443 335555555666666665543 444 358899999 999999999999999999
2777
2778
2779 Q sp|Q9BYF1|ACE2 574 VGAKNMNVRPLLNYFE 589 (805)
2780 Q Consensus 574 vgaknmnvrpllnyfe 589 (805)
2781 .|.. .+..+++.|+.
2782 T Consensus 667 ~G~~-~s~~~~l~~~~ 681 (683)
2783 T 5L43_B 667 RGRT-PRIEPLLDRRG 681 (683)
2784 T ss_dssp HSSS-CCSHHHHHHHT
2785 T ss_pred hCCC-CChHHHHHHcC
2786 Confidence 9986 88888888764
2787
2788
2789 No 32
2790 >1Y79_1 Peptidyl-Dipeptidase Dcp (E.C.3.4.15.5); hinge bending peptidyl dipeptidase; HET: TRP; 2.0A {Escherichia coli}
2791 Probab=99.44 E-value=4.5e-17 Score=163.19 Aligned_cols=501 Identities=14% Similarity=0.139 Sum_probs=281.7 Template_Neff=9.600
2792
2793 Q sp|Q9BYF1|ACE2 41 YQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMY-------------PLQEIQNLTVKLQLQALQQNGSSV 107 (805)
2794 Q Consensus 41 yqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmy-------------plqeiqnltvklqlqalqqngssv 107 (805)
2795 .-.+.+++-+.++.+++.-..-..+..+.+++..+..+=..+| .+.+-+...++..++....+|...
2796 T Consensus 70 ~~~~~~~~l~~~~~~~e~r~a~~~~~~~~~~~~~~~~~~~~ly~~l~~~~~~~~~~~l~~e~~r~l~~~l~~~~~~G~~L 149 (680)
2797 T 1Y79_1 70 RVTSVFFAMTAAHTNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKL 149 (680)
2798 T ss_pred HHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHccCHHHHHHHHHHHcCCCccCCCHHHHHHHHHHHHHHHHcCCCC
2799 Confidence 3455666667777555554445555555665544432111111 122223334555666677788765
2800
2801
2802 Q sp|Q9BYF1|ACE2 108 LSEDKSKRLNTILNT---MSTIYSTGKVC---------N--------PD----------------NPQECLLLEPGLNEI 151 (805)
2803 Q Consensus 108 lsedkskrlntilnt---mstiystgkvc---------n--------pd----------------npqeclllepglnei 151 (805)
2804 .++ +.+|+..+... +++.|+..-.. . |+ .+...-+-.|.+..+
2805 T Consensus 150 ~~~-~~~~l~~l~~~i~~l~~~f~~n~~~~~~~~~~~~~~~~~L~g~p~~~l~~~~~~a~~~~~~~~~~i~l~~~~~~~~ 228 (680)
2806 T 1Y79_1 150 AQA-DKAKLKVLNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPA 228 (680)
2807 T ss_pred CHH-HHHHHHHHHHHHHHHHHHHHHhcccccccccccCCCHHHHcCCCHHHHHHHHHHHHHcCCCCCeEeeCCCccHHHH
2808 Confidence 444 44666655443 22223211110 0 00 111122223567888
2809
2810
2811 Q sp|Q9BYF1|ACE2 152 MANSLDYNERLWAWESWRSEVG----KQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVE 227 (805)
2812 Q Consensus 152 mansldynerlwaweswrsevg----kqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedve 227 (805)
2813 |+++-|...|--+|..|.+... ....+++.+.+.+++++|+...|++|.+|+-.+.. ..+..++.+-..
2814 T Consensus 229 l~~~~d~~~R~~~~~a~~~~~~~~~~~~~~~~l~~lv~~R~~~A~llGy~s~~~~~l~~~m-------~~~~~~v~~~L~ 301 (680)
2815 T 1Y79_1 229 LAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIADQM-------AKTPEAALNFMR 301 (680)
2816 T ss_pred HHhCCCHHHHHHHHHHHHhccccCCccccHHHHHHHHHHHHHHHHHhCCCCHHHHHhcccC-------CCCHHHHHHHHH
2817 Confidence 9999999999999999975543 46789999999999999999999999999864431 223334444455
2818
2819
2820 Q sp|Q9BYF1|ACE2 228 HTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQR- 306 (805)
2821 Q Consensus 228 htfeeikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqr- 306 (805)
2822 ...+.++|++++.++.+++.....+ |+--...|...|-...+-. ...+++++.+.+-....+
2823 T Consensus 302 ~l~~~~~p~~~~e~~~l~~~~~~~~---------------g~~~l~~wD~~y~~~~~~~--~~~~~~~~~~~~yf~~~~v 364 (680)
2824 T 1Y79_1 302 EIVPAARQRASDELASIQAVIDKQQ---------------GGFSAQPWDWAFYAEQVRR--EKFDLDEAQLKPYFELNTV 364 (680)
2825 T ss_pred HHHHHhHHHHHHHHHHHHHHHHHhc---------------CCCCCCcccHHHHHHhHHh--hccCCCHHHHHhhCCHHHH
2826 Confidence 5567888999988888887554322 1111233433333222211 223343444433333332
2827
2828
2829 Q sp|Q9BYF1|ACE2 307 ----IFKEAEKFFVSVGLPN---MTQGFWENSM----------------LTDP----GNVQKAVCHPTAWD--LGKGDFR 357 (805)
2830 Q Consensus 307 ----ifkeaekffvsvglpn---mtqgfwensm----------------ltdp----gnvqkavchptawd--lgkgdfr 357 (805)
2831 +|+.+++.| |+-- ....+|..+. .-|+ |.-..+-|.+..-. ....+.+
2832 T Consensus 365 ~~~~l~~~~~~~f---g~~~~~~~~~~~W~~~v~~~~v~~~~~~~lg~~y~D~~~r~~K~~~~~~~~~~~~~~~~~~~p~ 441 (680)
2833 T 1Y79_1 365 LNEGVFWTANQLF---GIKFVERFDIPVYHPDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNKTHPV 441 (680)
2834 T ss_pred HHHhHHHHHHHHh---CCEEEEcCCCccccCCceEEEEEcCCCCEEEEEEEeCCCCCCCCCCCcccceecccCCCCCCCE
2835 Confidence 444555544 2111 0111233322 1121 22222223221000 0012344
2836
2837
2838 Q sp|Q9BYF1|ACE2 358 I-----------LMCTKVTMDDFLTAHHEMGHIQYDMAYAAQ-PFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLS 425 (805)
2839 Q Consensus 358 i-----------lmctkvtmddfltahhemghiqydmayaaq-pfllrnganegfheavgeimslsaatpkhlksiglls 425 (805)
2840 | -.|+.++.+|+.|.+||+||..+.+..... +.+...+..-.|.|+.+.+|..-+..|..|+.++.--
2841 T Consensus 442 v~~~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~l~~~~~~~ 521 (680)
2842 T 1Y79_1 442 IYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHY 521 (680)
2843 T ss_pred EEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhCCCCchhcCCCCcccccccchHhhHHHhcCHHHHHHHhhcC
2844 Confidence 4 267778899999999999999998776543 2222344678899999999999999999999876432
2845
2846
2847 Q sp|Q9BYF1|ACE2 426 PDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGE--IPKDQWMKKWWEMKREIVGVVEPVPHDETYC 498 (805)
2848 Q Consensus 426 pdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkge--ipkdqwmkkwwemkreivgvvepvphdetyc 498 (805)
2849 .+-+.-.+..++.|++ +++.++..+.+ ..++.+-+-...++ +..+++ .||+...+-.|+ .+.+ ..+.
2850 T Consensus 522 ~~~~~l~~~~~~~l~~~~~~~~~~~~~~~l~~-~~~D~~lh~~~~~~~~~~~~~~--~~~~~~~~~~~~-~~~~--~~~~ 595 (680)
2851 T 1Y79_1 522 QSGAAMPDELQQKMRNASLFNKGYEMSELLSA-ALLDMRWHCLEENEAMQDVDDF--ELRALVAENMDL-PAIP--PRYR 595 (680)
2852 T ss_pred CCCCCCCHHHHHHHHHHhhHHHHHHHHHHHHH-HHHHHHHhcCCCCCCCCChhHH--HHHHHHHHHHCC-CCCC--CCcc
2853 Confidence 1111112334555543 35555555544 46666555444332 333444 455544434465 2222 2333
2854
2855
2856 Q sp|Q9BYF1|ACE2 499 DPASLFHVSN-DYS--FIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLALENVV 574 (805)
2857 Q Consensus 499 dpaslfhvsn-dys--firyytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwtlalenvv 574 (805)
2858 +.+..|+.. +|. +..|....++.+++.+.+|+ +|++ +.++|+++. .+|..|.+.++.-.++...
2859 T Consensus 596 -~~~~~hi~~~~y~~~yysY~~s~v~a~~i~~~~~~----~~~~-------~~~~g~~~r~~~L~~G~s~~~~e~~~~fl 663 (680)
2860 T 1Y79_1 596 -SSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVE----QGGL-------TRENGLRFREAILSRGNSEDLERLYRQWR 663 (680)
2861 T ss_pred -ccccHHHHcCCcchHHHHHHHHHHHHHHHHHHHHH----hCCC-------CHHHHHHHHHHhhccCCCCCHHHHHHHHh
2862 Confidence 677777753 333 23444455555565555544 3443 257899998 8999999999999999998
2863
2864
2865 Q sp|Q9BYF1|ACE2 575 GAKNMNVRPLLNYF 588 (805)
2866 Q Consensus 575 gaknmnvrpllnyf 588 (805)
2867 |.. .+..+++.++
2868 T Consensus 664 G~~-~~~~~~l~~~ 676 (680)
2869 T 1Y79_1 664 GKA-PKIMPMLQHR 676 (680)
2870 T ss_pred CCC-CCHHHHHHHc
2871 Confidence 876 7777777765
2872
2873
2874 No 33
2875 >4KA7_A Oligopeptidase A, short endogenous peptide; Protease, Mitochondria, chloroplast, HYDROLASE-HYDROLASE SUBSTRATE; HET: GOL; 1.8A {Arabidopsis thaliana}
2876 Probab=99.43 E-value=5.8e-17 Score=163.74 Aligned_cols=407 Identities=15% Similarity=0.103 Sum_probs=238.2 Template_Neff=9.500
2877
2878 Q sp|Q9BYF1|ACE2 144 LEPGLNEIMANSLDYNERLWAWESWRSEVG---KQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRG 220 (805)
2879 Q Consensus 144 lepglneimansldynerlwaweswrsevg---kqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrg 220 (805)
2880 -.|.+..+|.++-|...|--+|++|.+..+ ....+++.+.+.+++++|+...|++|.+|+-.+..+ +..
2881 T Consensus 239 ~~~~~~~il~~~~d~~~Rk~~~~a~~~~~~~~~~~~~~~l~~l~~~R~~~A~llGy~s~a~~~l~~~~~--------~~~ 310 (714)
2882 T 4KA7_A 239 DAPSYLPVMQHAKNRALREEVYRAYLSRASSGDLDNTAIIDQILKLRLEKAKLLGYNNYAEVSMAMKMA--------TVE 310 (714)
2883 T ss_dssp SHHHHHHHHHHCCCHHHHHHHHHHHHTTTCSGGGCCHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSSC--------CHH
2884 T ss_pred CCccHHHHHHhCCCHHHHHHHHHHHHcccCCCCcChHHHHHHHHHHHHHHHHHhCCCCHHHHHHHHhcC--------CHH
2885 Confidence 346678899999899999999999987654 568899999999999999999999999998654333 222
2886
2887
2888 Q sp|Q9BYF1|ACE2 221 QLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK-PNIDVTDAMVD 299 (805)
2889 Q Consensus 221 qliedvehtfeeikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqk-pnidvtdamvd 299 (805)
2890 .+.+-++...+.++|+++..++.++......+. . |.---..|...|-.. ++-+. .+++ ...+.
2891 T Consensus 311 ~v~~~L~~l~~~~~~~~~~~~~~l~~~~~~~~~--------~-----~~~~l~~wD~~y~~~-~~~~~~~~~~--~~~~~ 374 (714)
2892 T 4KA7_A 311 KAAELLEKLRSASWDAAVQDMEDLKSFAKNQGA--------A-----ESDSMTHWDTTFWSE-RLRESKYDIN--EEELR 374 (714)
2893 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTC--------G-----GGGSCCTTTHHHHHH-HHHHHHHCCC--HHHHG
2894 T ss_pred HHHHHHHHHHHhcHHHHHHHHHHHHHHHHHcCC--------C-----CCCCCCcccHHHHHH-HHHHhcCCCC--HHHHH
2895 Confidence 333444445556677777666666643222111 0 000012333332222 11111 1111 11111
2896
2897
2898 Q sp|Q9BYF1|ACE2 300 QAWD----AQRIFKEAEKFFVSVGLPNMT--QGFWENSM----------------LTDP----G-NVQKAVCHPTAWD-- 350 (805)
2899 Q Consensus 300 qawd----aqrifkeaekffvsvglpnmt--qgfwensm----------------ltdp----g-nvqkavchptawd-- 350 (805)
2900 .-.. ...+|+-++++|- +++.... ...|..+. .-|+ | ....+.|++..-.
2901 T Consensus 375 ~yf~~~~~~~~i~~~~~~~f~-l~~~~~~~~~~~w~~~v~~~~v~~~~~~~~g~~~lD~~~r~~kk~~g~~~~~~~~~~~ 453 (714)
2902 T 4KA7_A 375 PYFSLPKVMDGLFSLAKTLFG-IDIEPADGLAPVWNNDVRFYRVKDSSGNPIAYFYFDPYSRPSEKRGGAWMDEVVSRSR 453 (714)
2903 T ss_dssp GGCBHHHHHHHHHHHHHHHHC-CEEEECTTSSCCSSTTCEEEEEECTTSCEEEEEEEEEECCTTTSCSSCEEEEEECCBS
2904 T ss_pred hcCCHHHHHHHHHHHHHHHHC-cEEEECCCCCCcccCCcEEEEEEcCCCCeEEEEEECCCCCCCCCCCCcccccccccch
2905 Confidence 1111 2345555566655 4444332 12343322 1222 2 1222334322110
2906
2907
2908 Q sp|Q9BYF1|ACE2 351 -LG-----KGDFRILMC-----------TKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLR--NGANEGFHEAVGEIMSLS 411 (805)
2909 Q Consensus 351 -lg-----kgdfrilmc-----------tkvtmddfltahhemghiqydmayaaqpfllr--nganegfheavgeimsls 411 (805)
2910 ++ .....|+|+ +.++.+|+.|.+||+||..+.+....+...+. .+..-.|.|+.+.+|..-
2911 T Consensus 454 ~~~~~~~~~~~p~v~~~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~~~~g~~~~~~d~~E~~S~~~E~~ 533 (714)
2912 T 4KA7_A 454 VMAQKGSSVRLPVAHMVCNQTPPVGDKPSLMTFREVETVFHQFGHALQHMLTKQDEGLVAGIRNIEWDAVELPSQFMENW 533 (714)
2913 T ss_dssp TTCCTTSSCBCCEEEEEEEECCCCTTSCCBCCHHHHHHHHHHHHHHHHHHSCCCCCGGGSTTTTCCGGGTTHHHHHHHGG
2914 T ss_pred hHhcCCCceeccEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHhhCCCchhhcCccccccccchhcHHHHHHH
2915 Confidence 00 123456654 44569999999999999999887765554444 256889999999999999
2916
2917
2918 Q sp|Q9BYF1|ACE2 412 AATPKHLKSIGLLSPDFQEDNETEINFLLKQ-----ALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVG 486 (805)
2919 Q Consensus 412 aatpkhlksigllspdfqedneteinfllkq-----altivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivg 486 (805)
2920 +..|..|+.++.-..+-++..+..++.+++. ++.++. .++-..++.+.+-...+.-| ..+-+-|+++..+. |
2921 T Consensus 534 ~~~~~~L~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~-~~~~~~~D~~lh~~~~~~~~-~~~~~~~~~~~~~~-~ 610 (714)
2922 T 4KA7_A 534 CYHRDTLMSIAKHYETGETLPEEVYKKLLAARTFRAGSFSLR-QLKFASVDLELHTKYVPGGP-ESIYDVDQRVSVKT-Q 610 (714)
2923 T ss_dssp GGSHHHHHHHCBCTTTCCBCCHHHHHHHHHTTTTTHHHHHHH-HHHHHHHHHHHTTTCCTTSS-CCHHHHHHHHHHHH-C
2924 T ss_pred hcCHHHHHHHhhccCCCCCCCHHHHHHHHHHhhhchHHHHHH-HHHHHHHHHHHHhcCCCCCC-CCHHHHHHHHHHHh-C
2925 Confidence 9999999887653322222233446666654 555544 55667788877776643323 23335577664444 3
2926
2927
2928 Q sp|Q9BYF1|ACE2 487 VVEPVPHDETYCDPASLFHVSN-DY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGK 562 (805)
2929 Q Consensus 487 vvepvphdetycdpaslfhvsn-dy--sfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgk 562 (805)
2930 -+.+.+ ..-.+.+..|+-. +| .+..|-...++.+++-+.+|+ +|+. +...+.++|+++. ++|..|.
2931 T Consensus 611 ~~~~~~---~~~~~~~~~hi~~~~y~a~yY~Y~~a~v~a~~i~~~f~~----~~~~---~~~~~~~~g~~~~~~~L~~G~ 680 (714)
2932 T 4KA7_A 611 VIPPLP---EDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAFSAFED----AGLD---DIKAVKETGQRFRNTILALGG 680 (714)
2933 T ss_dssp SSCCCT---TCCGGGGCHHHHSSTTTTTTTHHHHHHHHHHHHHHHHHH----HCTT---CHHHHHHHHHHHHTTTTTCTT
2934 T ss_pred CCCCCC---CCcccccchhhhccCcchHHHHHHHHHHHHHHHHHHHHH----cCCC---chHHHHHHHHHHHHHHhhcCC
2935 Confidence 232211 1124456666643 44 444554455555555554444 2321 2234678999999 9999999
2936
2937
2938 Q sp|Q9BYF1|ACE2 563 SEPWTLALENVVGAKNMNVRPLLNYFE 589 (805)
2939 Q Consensus 563 sepwtlalenvvgaknmnvrpllnyfe 589 (805)
2940 +.++.-.++...|.. .+..+++.++.
2941 T Consensus 681 s~~~~e~~~~~~g~~-~~~~~~l~~~~ 706 (714)
2942 T 4KA7_A 681 GKAPLKVFVEFRGRE-PSPEPLLRHNG 706 (714)
2943 T ss_dssp SSCHHHHHHHHHSSC-CCSHHHHHHTT
2944 T ss_pred CCCHHHHHHHHhCCC-CChHHHHHHcC
2945 Confidence 999999998877764 66777777653
2946
2947
2948 No 34
2949 >2KNC_B Integrin alpha-IIb, Integrin beta-3; integrin, transmembrane signaling, protein structure; NMR {Homo sapiens}
2950 Probab=92.66 E-value=0.036 Score=45.32 Aligned_cols=31 Identities=13% Similarity=0.358 Sum_probs=11.0 Template_Neff=7.700
2951
2952 Q sp|Q9BYF1|ACE2 733 PPNQPPVSIWLIVFGVVMGVIVVGIVILIFT 763 (805)
2953 Q Consensus 733 ppnqppvsiwlivfgvvmgvivvgivilift 763 (805)
2954 .+...+.+.+.|+.|++.|++++|++++++.
2955 T Consensus 2 ~~~~~~~~~~~i~g~vvggiv~l~ll~~~i~ 32 (79)
2956 T 2KNC_B 2 AMGSKGPDILVVLLSVMGAILLIGLAALLIW 32 (79)
2957 T ss_dssp CSSCS-------------SHHHHHHHHHHHH
2958 T ss_pred CCCCCcCchHHHHHHHHHHHHHHHHHHHHHH
2959 Confidence 3455677788888888888887777654433
2960
2961
2962 No 35
2963 >2L8S_A Integrin alpha-1; Integrin Alpha1, Transmembrane Region, Detergent; NMR {Homo sapiens}
2964 Probab=87.55 E-value=0.29 Score=40.19 Aligned_cols=43 Identities=26% Similarity=0.506 Sum_probs=30.9 Template_Neff=5.400
2965
2966 Q sp|Q9BYF1|ACE2 736 QPPVSIWLIVFGVVMGVIVVGIVILIF--TGIRDRKKKNKARSGE 778 (805)
2967 Q Consensus 736 qppvsiwlivfgvvmgvivvgivilif--tgirdrkkknkarsge 778 (805)
2968 .+++.+|.|+.+++.|++++++++++. .|.-.||++.+....|
2969 T Consensus 4 ~~~~p~wiii~svl~GlllL~iii~iL~K~GFFkRk~~~~~~~~~ 48 (54)
2970 T 2L8S_A 4 PGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEKLE 48 (54)
2971 T ss_dssp CCCCCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCSCCCCC--
2972 T ss_pred CCCccHHHHHHHHHHHHHHHHHHHHHHHHcCCCCCCcchHHHHhc
2973 Confidence 467889999999999998877765554 5777777766655444
2974
2975
2976 No 36
2977 >2N2A_B Receptor tyrosine-protein kinase erbB-2; HER2, ErbB2, Tyrosine kinase, Activation; NMR {Homo sapiens}
2978 Probab=86.49 E-value=0.38 Score=38.36 Aligned_cols=30 Identities=27% Similarity=0.208 Sum_probs=13.8 Template_Neff=7.000
2979
2980 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
2981 Q Consensus 742 wlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
2982 ..|+.||+.|++++.++++++.-++.|+++
2983 T Consensus 9 ~~I~~~Vvg~l~~~~~i~~~~~~~~Rrr~~ 38 (58)
2984 T 2N2A_B 9 TSIISAVVGILLVVVLGVVFGILIKRRQQK 38 (58)
2985 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHTTC
2986 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHhHHHH
2987 Confidence 345556655555444444333333434333
2988
2989
2990 No 37
2991 >2KNC_A Integrin alpha-IIb, Integrin beta-3; integrin, transmembrane signaling, protein structure; NMR {Homo sapiens}
2992 Probab=85.75 E-value=0.45 Score=38.68 Aligned_cols=40 Identities=23% Similarity=0.570 Sum_probs=29.1 Template_Neff=5.900
2993
2994 Q sp|Q9BYF1|ACE2 735 NQPPVSIWLIVFGVVMGVIVVGIVILI--FTGIRDRKKKNKA 774 (805)
2995 Q Consensus 735 nqppvsiwlivfgvvmgvivvgivili--ftgirdrkkknka 774 (805)
2996 ..+++++|.|+.+++.|++++++++++ -.|...||++...
2997 T Consensus 6 ~~~~~~~wiiv~svl~GlllL~li~~iL~K~GFFkRk~~~~~ 47 (54)
2998 T 2KNC_A 6 EERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLE 47 (54)
2999 T ss_dssp TTTTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTCCSCC
3000 T ss_pred ccccccHHHHHHHHHHHHHHHHHHHHHHHHcCccccCCCccc
3001 Confidence 345788999999999999887766544 4577777665543
3002
3003
3004 No 38
3005 >2M3E_A Integrin alpha-L; integrin alpah L TM domain; NMR {Homo sapiens}
3006 Probab=85.42 E-value=0.48 Score=38.20 Aligned_cols=39 Identities=18% Similarity=0.400 Sum_probs=29.1 Template_Neff=5.700
3007
3008 Q sp|Q9BYF1|ACE2 736 QPPVSIWLIVFGVVMGVIVVGIVILIF--TGIRDRKKKNKA 774 (805)
3009 Q Consensus 736 qppvsiwlivfgvvmgvivvgivilif--tgirdrkkknka 774 (805)
3010 ..++.+|.|+.+++.|++++.+++++. .|...||++.+.
3011 T Consensus 7 ~~~~~~wiii~svi~GlllL~ii~~iL~K~GFFkRk~~~~~ 47 (50)
3012 T 2M3E_A 7 YEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKM 47 (50)
3013 T ss_dssp TTCCCHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGSCCCCC
3014 T ss_pred chhhcHHHHHHHHHHHHHHHHHHHHHHHHcCcchhhhhHHH
3015 Confidence 457889999999999998877765554 566677666543
3016
3017
3018 No 39
3019 >6J8H_C Sodium channel subunit beta-2, Sodium; voltage-gated sodium channel, MEMBRANE PROTEIN; HET: 9SL, NAG;{Homo sapiens}
3020 Probab=84.27 E-value=0.6 Score=37.23 Aligned_cols=8 Identities=13% Similarity=0.576 Sum_probs=3.9 Template_Neff=12.500
3021
3022 Q sp|Q9BYF1|ACE2 591 LFTWLKDQ 598 (805)
3023 Q Consensus 591 lftwlkdq 598 (805)
3024 -++|.++.
3025 T Consensus 64 ~v~W~~~~ 71 (215)
3026 T 6J8H_C 64 SLNWTYQE 71 (215)
3027 T ss_pred EEEEEEec
3028 Confidence 34555543
3029
3030
3031 No 40
3032 >2N9Y_B Integrin alpha-IIb, Integrin beta-3; transmembrane complex, integrin receptor, cell; NMR {Homo sapiens}
3033 Probab=83.96 E-value=0.63 Score=34.96 Aligned_cols=30 Identities=13% Similarity=0.345 Sum_probs=21.3 Template_Neff=7.200
3034
3035 Q sp|Q9BYF1|ACE2 737 PPVSIWLIVFGVVMGVIVVGIVILIFTGIR 766 (805)
3036 Q Consensus 737 ppvsiwlivfgvvmgvivvgiviliftgir 766 (805)
3037 ++.+++.|+.|++-|++++|+++++..-.+
3038 T Consensus 5 ~~~~~~~I~ggvvggi~ligli~lli~~~~ 34 (43)
3039 T 2N9Y_B 5 KCPDILVVLLSVMGAILLIGLAPLLIWKLL 34 (43)
3040 T ss_dssp SSCCHHHHHHHHHHHHHHHHHHHHHHHHHH
3041 T ss_pred CCCcHHHHHHHHHHHHHHHHHHHHHHHHHH
3042 Confidence 345667788899999888887766554443
3043
3044
3045 No 41
3046 >6JXR_n T-cell surface glycoprotein CD3 zeta; IMMUNE SYSTEM;{Homo sapiens}
3047 Probab=83.38 E-value=0.7 Score=37.95 Aligned_cols=7 Identities=14% Similarity=0.700 Sum_probs=3.7 Template_Neff=12.900
3048
3049 Q sp|Q9BYF1|ACE2 591 LFTWLKD 597 (805)
3050 Q Consensus 591 lftwlkd 597 (805)
3051 -+.|.++
3052 T Consensus 154 ~~~W~~~ 160 (291)
3053 T 6JXR_n 154 ELSWWVN 160 (291)
3054 T ss_pred eEEEEEC
3055 Confidence 4556553
3056
3057
3058 No 42
3059 >2K9J_A Integrin alpha-IIb light chain, Integrin; integrin, transmembrane complex, Cell adhesion; NMR {Homo sapiens}
3060 Probab=83.01 E-value=0.74 Score=35.92 Aligned_cols=39 Identities=26% Similarity=0.696 Sum_probs=28.8 Template_Neff=5.800
3061
3062 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIF--TGIRDRKK 770 (805)
3063 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgivilif--tgirdrkk 770 (805)
3064 ||+..+++.+|.|+.+++.|++++.+++++. .|.-.||+
3065 T Consensus 1 ~~~~~~~~~~wiii~svl~GlllL~li~~iL~K~GFFkRk~ 41 (42)
3066 T 2K9J_A 1 GALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 41 (42)
3067 T ss_dssp CCSSCSCCHHHHHHHHHHHHHHHHHHHHHHHHTTTSSCCCC
3068 T ss_pred CchhhccccHHHHHHHHHHHHHHHHHHHHHHHHhCccccCC
3069 Confidence 5667788999999999999998887765554 34444443
3070
3071
3072 No 43
3073 >2N5S_A Epidermal growth factor receptor (E.C.2.7.10.1); transmembrane, TRANSFERASE; NMR {Homo sapiens}
3074 Probab=82.67 E-value=0.79 Score=34.05 Aligned_cols=10 Identities=30% Similarity=0.504 Sum_probs=4.2 Template_Neff=8.700
3075
3076 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVI 753 (805)
3077 Q Consensus 744 ivfgvvmgvi 753 (805)
3078 |+.|++.|++
3079 T Consensus 8 i~~gvv~~~~ 17 (54)
3080 T 2N5S_A 8 IATGMVGALL 17 (54)
3081 T ss_dssp TTHHHHHHHH
3082 T ss_pred HHHHHHHHHH
3083 Confidence 3444444433
3084
3085
3086 No 44
3087 >4UM8_D INTEGRIN ALPHA-V, INTEGRIN BETA-6; IMMUNE SYSTEM, CELL SURFACE RECEPTOR; HET: CAC, SO4, NAG, CA, MAN, BMA; 2.852A {HOMO SAPIENS}
3088 Probab=80.82 E-value=1 Score=48.98 Aligned_cols=25 Identities=32% Similarity=0.786 Sum_probs=0.0 Template_Neff=9.100
3089
3090 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3091 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3092 +..+|.|++|++.|++++|+++|+.
3093 T Consensus 705 ~~~~~~i~~gvv~~ivli~l~~l~i 729 (788)
3094 T 4UM8_D 705 PPNIPMIMLGVSLAILLIGVVLLCI 729 (788)
3095 T ss_dssp -------------------------
3096 T ss_pred CCCHHHHHHHHHHHHHHHHHHHHHH
3097 Confidence 5667788889888888888776654
3098
3099
3100 No 45
3101 >4UM8_B INTEGRIN ALPHA-V, INTEGRIN BETA-6; IMMUNE SYSTEM, CELL SURFACE RECEPTOR; HET: MAN, NAG, CA, SO4, CAC, BMA; 2.852A {HOMO SAPIENS}
3102 Probab=78.69 E-value=1.4 Score=48.08 Aligned_cols=25 Identities=32% Similarity=0.786 Sum_probs=19.0 Template_Neff=9.100
3103
3104 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3105 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3106 +..+|.|++|++.|++++|+++|+.
3107 T Consensus 705 ~~~~~~i~~gvv~~ivll~l~~lli 729 (788)
3108 T 4UM8_B 705 PPNIPMIMLGVSLAILLIGVVLLCI 729 (788)
3109 T ss_pred CchHHHHHHHHHHHHHHHHHHHHHH
3110 Confidence 5677888888888888887766543
3111
3112
3113 No 46
3114 >1AFO_A GLYCOPHORIN A; INTEGRAL MEMBRANE PROTEIN, HUMAN GLYCOPHORIN; NMR {Homo sapiens} SCOP: j.35.1.1
3115 Probab=75.93 E-value=1.9 Score=35.46 Aligned_cols=37 Identities=46% Similarity=0.680 Sum_probs=25.9 Template_Neff=2.500
3116
3117 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3118 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3119 .++-+.|+ |.+|+|||+.|+ +|++++|-..||.-+||
3120 T Consensus 4 ~h~fs~p~-i~lII~~VmaGI--IG~Il~i~y~I~rl~kk 40 (40)
3121 T 1AFO_A 4 AHHFSEPE-ITLIIFGVMAGV--IGTILLISYGIRRLIKK 40 (40)
3122 T ss_dssp SCCSSCCH-HHHHHHHHHHHH--HHHHHHHHHHHHHHSCC
3123 T ss_pred ccCCChHH-HHHHHHHHHHHH--HHHHHHHHHHHHHHhcC
3124 Confidence 34445555 789999999987 46777777777765554
3125
3126
3127 No 47
3128 >6A69_B Plasma membrane calcium-transporting ATPase 1; Membrane protein, STRUCTURAL PROTEIN; HET: NAG; 4.11A {Homo sapiens}
3129 Probab=75.89 E-value=1.9 Score=35.66 Aligned_cols=15 Identities=13% Similarity=0.375 Sum_probs=6.6 Template_Neff=12.700
3130
3131 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGVIVVG 756 (805)
3132 Q Consensus 742 wlivfgvvmgvivvg 756 (805)
3133 +.+++|++++++++.
3134 T Consensus 224 ~~~~~~~~~~~~~~~ 238 (282)
3135 T 6A69_B 224 LWPFLGILAEIIILV 238 (282)
3136 T ss_pred HHHHHHHHHHHHHHH
3137 Confidence 334445444444433
3138
3139
3140 No 48
3141 >6AGF_B Sodium channel protein PaFPC1, Mu-diguetoxin-Dc1a; sodium channel, MEMBRANE PROTEIN; HET: 6OU, 9Z9, NAG, BMA; 3.2A {Homo sapiens}
3142 Probab=75.28 E-value=2 Score=35.68 Aligned_cols=22 Identities=18% Similarity=0.176 Sum_probs=0.4 Template_Neff=11.700
3143
3144 Q sp|Q9BYF1|ACE2 773 KARSGENPYASIDISKGENNPGF 795 (805)
3145 Q Consensus 773 karsgenpyasidiskgennpgf 795 (805)
3146 +.+..+.+|+.+... ..+|+..
3147 T Consensus 192 ~~~~~~~~~~~~~~~-~~~~~~~ 213 (218)
3148 T 6AGF_B 192 AAQENASEYLAITSE-SKENCTG 213 (218)
3149 T ss_dssp C----------------------
3150 T ss_pred HHHhhHhhhcccChh-hhhcccc
3151 Confidence 344446677766533 3344433
3152
3153
3154 No 49
3155 >6J8J_B Sodium channel subunit beta-2, Sodium; voltage-gated sodium channel, MEMBRANE PROTEIN; HET: 9SR, NAG;{Homo sapiens}
3156 Probab=75.28 E-value=2 Score=35.68 Aligned_cols=22 Identities=18% Similarity=0.176 Sum_probs=11.0 Template_Neff=11.700
3157
3158 Q sp|Q9BYF1|ACE2 773 KARSGENPYASIDISKGENNPGF 795 (805)
3159 Q Consensus 773 karsgenpyasidiskgennpgf 795 (805)
3160 +.+..+.+|+.+... ..+|+..
3161 T Consensus 192 ~~~~~~~~~~~~~~~-~~~~~~~ 213 (218)
3162 T 6J8J_B 192 AAQENASEYLAITSE-SKENCTG 213 (218)
3163 T ss_pred HHHhhHhhhcccChh-hhhcccc
3164 Confidence 344446677766533 3344433
3165
3166
3167 No 50
3168 >6C14_A Protocadherin-15, LHFPL tetraspan subfamily member; PCDH15, LHFPL5, protocadherin, tip link;{Mus musculus}
3169 Probab=74.52 E-value=2.2 Score=40.59 Aligned_cols=23 Identities=4% Similarity=0.128 Sum_probs=12.6 Template_Neff=10.000
3170
3171 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVIL 760 (805)
3172 Q Consensus 738 pvsiwlivfgvvmgvivvgivil 760 (805)
3173 +..+.+|+++++++++++.++++
3174 T Consensus 238 ~~~~~li~laill~l~~lili~~ 260 (337)
3175 T 6C14_A 238 YTEGALLALAFIIILCCIPAILV 260 (337)
3176 T ss_dssp SHHHHHHHHHHHHHHHHHHHHHH
3177 T ss_pred HHHHHHHHHHHHHHHHHHHHHHH
3178 Confidence 33556677776666654433333
3179
3180
3181 No 51
3182 >6UJB_B Integrin alpha-V, Integrin beta-8, C6D4; glycoprotein, adhesion, signaling, SIGNALING PROTEIN-IMMUNE; HET: MAN, NAG, BMA; 3.51A {Homo sapiens}
3183 Probab=73.28 E-value=2.5 Score=45.78 Aligned_cols=25 Identities=16% Similarity=0.359 Sum_probs=0.0 Template_Neff=9.100
3184
3185 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3186 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3187 +..+|.|++|++.+++++++++|++
3188 T Consensus 637 ~~~~~~i~~~v~~~illi~l~~l~i 661 (727)
3189 T 6UJB_B 637 SPSYLRIFFIIFIVTFLIGLLKVLI 661 (727)
3190 T ss_dssp -------------------------
3191 T ss_pred CccHHHHHHHHHHHHHHHHHHHHHH
3192 Confidence 4567788888888887777665543
3193
3194
3195 No 52
3196 >6UJA_B Integrin alpha-V, Integrin beta-8, Transforming; glycoprotein, adhesion, signaling, SIGNALING PROTEIN; HET: MAN, BMA, NAG; 3.3A {Homo sapiens}
3197 Probab=73.28 E-value=2.5 Score=45.78 Aligned_cols=25 Identities=16% Similarity=0.359 Sum_probs=0.0 Template_Neff=9.100
3198
3199 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3200 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3201 +..+|.|++|++.+++++++++|++
3202 T Consensus 637 ~~~~~~i~~~v~~~illi~l~~l~i 661 (727)
3203 T 6UJA_B 637 SPSYLRIFFIIFIVTFLIGLLKVLI 661 (727)
3204 T ss_dssp -------------------------
3205 T ss_pred CccHHHHHHHHHHHHHHHHHHHHHH
3206 Confidence 4567788888888887777665543
3207
3208
3209 No 53
3210 >2M20_A Epidermal growth factor receptor (E.C.2.7.10.1); Transmembrane, Cell Signaling, Juxtamembrane, SIGNALING; NMR {Homo sapiens}
3211 Probab=72.68 E-value=2.6 Score=32.92 Aligned_cols=10 Identities=30% Similarity=0.511 Sum_probs=4.3 Template_Neff=7.900
3212
3213 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVI 753 (805)
3214 Q Consensus 744 ivfgvvmgvi 753 (805)
3215 |+.|||.|++
3216 T Consensus 5 i~~~vvg~~~ 14 (60)
3217 T 2M20_A 5 IATGLVGALL 14 (60)
3218 T ss_dssp HHHHHHHHHH
3219 T ss_pred HHHHHHHHHH
3220 Confidence 3444444433
3221
3222
3223 No 54
3224 >5OR7_C Capsid protein, CMRF35-like molecule 1; CR10, sCD300lf, complex, VIRAL PROTEIN; 2.046A {Murine norovirus GV/CR10/2005/USA}
3225 Probab=72.61 E-value=2.7 Score=38.46 Aligned_cols=6 Identities=17% Similarity=0.506 Sum_probs=2.6 Template_Neff=11.000
3226
3227 Q sp|Q9BYF1|ACE2 592 FTWLKD 597 (805)
3228 Q Consensus 592 ftwlkd 597 (805)
3229 +.|.++
3230 T Consensus 52 v~W~~~ 57 (330)
3231 T 5OR7_C 52 KYWCQG 57 (330)
3232 T ss_pred EEEEEC
3233 Confidence 344443
3234
3235
3236 No 55
3237 >2MFR_A Insulin receptor (E.C.2.7.10.1); insulin recepotr, membrane protein, detergent; NMR {Homo sapiens}
3238 Probab=69.03 E-value=3.6 Score=33.93 Aligned_cols=38 Identities=21% Similarity=0.174 Sum_probs=19.5 Template_Neff=5.900
3239
3240 Q sp|Q9BYF1|ACE2 740 SIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGEN 779 (805)
3241 Q Consensus 740 siwlivfgvvmgvivvgiviliftgirdrkkknkarsgen 779 (805)
3242 +++++++|.+..++++.+++. ...-.+|||+..|+||.
3243 T Consensus 15 ~~~~iiI~pvi~iilii~~~~--~~~~~~kKr~~~~~~~~ 52 (57)
3244 T 2MFR_A 15 NIAKIIIGPLIFVFLFSVVIG--SIYLFLRKRQPDGPLEH 52 (57)
3245 T ss_dssp HHHHHHHHHHHHHHHHHHHHH--HHHHHHTSSCCCCSSSC
3246 T ss_pred hHHHHHHHHHHHHHHHHHHHH--HHHHHHhccCCCCCCCC
3247 Confidence 344555555544443332222 22344566777788874
3248
3249
3250 No 56
3251 >4U0Q_B Plasmodium falciparum Reticulocyte-binding protein homologue; Malaria Erythrocyte invasion, signaling protein; 3.1A {Plasmodium falciparum}
3252 Probab=67.25 E-value=4.2 Score=33.78 Aligned_cols=13 Identities=31% Similarity=0.493 Sum_probs=0.0 Template_Neff=12.500
3253
3254 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVIVVG 756 (805)
3255 Q Consensus 744 ivfgvvmgvivvg 756 (805)
3256 +++|++++++++.
3257 T Consensus 211 ~~~~~~~~~~~~~ 223 (269)
3258 T 4U0Q_B 211 PFLGIVAEVLVLV 223 (269)
3259 T ss_dssp -------------
3260 T ss_pred HHHHHHHHHHHHH
3261 Confidence 3445544444443
3262
3263
3264 No 57
3265 >5A2F_A CD166 ANTIGEN; CELL ADHESION, ALCAM, ACTIVATED LEUKOCYTE; HET: EDO, NAG; 1.86A {HOMO SAPIENS}
3266 Probab=63.73 E-value=5.5 Score=38.68 Aligned_cols=11 Identities=18% Similarity=0.585 Sum_probs=0.0 Template_Neff=11.600
3267
3268 Q sp|Q9BYF1|ACE2 589 EPLFTWLKDQN 599 (805)
3269 Q Consensus 589 eplftwlkdqn 599 (805)
3270 .|.++|.++..
3271 T Consensus 442 ~~~i~W~~~~~ 452 (583)
3272 T 5A2F_A 442 KPAIQWTITGS 452 (583)
3273 T ss_dssp -----------
3274 T ss_pred CCEEEEEECCc
3275 Confidence 35566766543
3276
3277
3278 No 58
3279 >2KLU_A T-cell surface glycoprotein CD4; Protein, Cell membrane, Disulfide bond; NMR {Homo sapiens}
3280 Probab=59.80 E-value=7.3 Score=30.35 Aligned_cols=9 Identities=56% Similarity=0.881 Sum_probs=3.7 Template_Neff=8.800
3281
3282 Q sp|Q9BYF1|ACE2 744 IVFGVVMGV 752 (805)
3283 Q Consensus 744 ivfgvvmgv 752 (805)
3284 +++|++.++
3285 T Consensus 12 ~~vg~~~~~ 20 (70)
3286 T 2KLU_A 12 IVLGGVAGL 20 (70)
3287 T ss_dssp HHHHHHHHH
3288 T ss_pred HHHHHHHHH
3289 Confidence 344444443
3290
3291
3292 No 59
3293 >6ENY_C Beta-2-microglobulin, Tapasin, Protein disulfide-isomerase A3; adaptive immunity, antigen processing, chaperone; HET: BGC, MAN, NAG; 5.8A {Homo sapiens}
3294 Probab=58.02 E-value=8.2 Score=37.78 Aligned_cols=9 Identities=11% Similarity=-0.142 Sum_probs=4.5 Template_Neff=10.300
3295
3296 Q sp|Q9BYF1|ACE2 539 LHKCDISNS 547 (805)
3297 Q Consensus 539 lhkcdisns 547 (805)
3298 .+.|.+.+.
3299 T Consensus 248 ~Y~C~~~~~ 256 (428)
3300 T 6ENY_C 248 TYLATIHLP 256 (428)
3301 T ss_pred EEEEEEEcC
3302 Confidence 455555443
3303
3304
3305 No 60
3306 >1S7Q_A H-2 class I histocompatibility antigen; LCMV, MHC class I, immune; 1.99A {Mus musculus} SCOP: d.19.1.1, b.1.1.2
3307 Probab=57.91 E-value=8.2 Score=37.47 Aligned_cols=11 Identities=27% Similarity=0.314 Sum_probs=0.0 Template_Neff=9.700
3308
3309 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGV 752 (805)
3310 Q Consensus 742 wlivfgvvmgv 752 (805)
3311 +.++.+++.++
3312 T Consensus 285 ~~~~~~~~~~~ 295 (348)
3313 T 1S7Q_A 285 ATVAVLVVLGA 295 (348)
3314 T ss_dssp -----------
3315 T ss_pred HHHHHHHHHHH
3316 Confidence 43333444343
3317
3318
3319 No 61
3320 >1S7S_A H-2 class I histocompatibility antigen; LCMV, MHC class I, immune; 1.99A {Mus musculus} SCOP: d.19.1.1, b.1.1.2
3321 Probab=57.91 E-value=8.2 Score=37.47 Aligned_cols=11 Identities=27% Similarity=0.314 Sum_probs=0.0 Template_Neff=9.700
3322
3323 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGV 752 (805)
3324 Q Consensus 742 wlivfgvvmgv 752 (805)
3325 +.++.+++.++
3326 T Consensus 285 ~~~~~~~~~~~ 295 (348)
3327 T 1S7S_A 285 ATVAVLVVLGA 295 (348)
3328 T ss_dssp -----------
3329 T ss_pred HHHHHHHHHHH
3330 Confidence 43333444343
3331
3332
3333 No 62
3334 >2WY3_A MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE; IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX, IMMUNE; HET: PEU, NAG, ACT; 1.8A {HUMAN HERPESVIRUS 5 STRAIN AD169}
3335 Probab=57.28 E-value=8.6 Score=35.83 Aligned_cols=9 Identities=33% Similarity=0.674 Sum_probs=4.8 Template_Neff=10.500
3336
3337 Q sp|Q9BYF1|ACE2 591 LFTWLKDQN 599 (805)
3338 Q Consensus 591 lftwlkdqn 599 (805)
3339 .++|.++..
3340 T Consensus 214 ~~~W~~~~~ 222 (319)
3341 T 2WY3_A 214 TLTWRQDGV 222 (319)
3342 T ss_pred EEEEEECCE
3343 Confidence 356666543
3344
3345
3346 No 63
3347 >6JXR_f T-cell surface glycoprotein CD3 zeta; IMMUNE SYSTEM;{Homo sapiens}
3348 Probab=55.13 E-value=9.8 Score=32.92 Aligned_cols=14 Identities=14% Similarity=-0.228 Sum_probs=6.0 Template_Neff=10.700
3349
3350 Q sp|Q9BYF1|ACE2 741 IWLIVFGVVMGVIV 754 (805)
3351 Q Consensus 741 iwlivfgvvmgviv 754 (805)
3352 +..|++|++.++++
3353 T Consensus 130 i~~iv~g~~~~~l~ 143 (207)
3354 T 6JXR_f 130 VATIVIVDICITGG 143 (207)
3355 T ss_pred HHHHHHHHHHHHHH
3356 Confidence 33344554444333
3357
3358
3359 No 64
3360 >3LB6_C Interleukin-13, Interleukin-13 receptor subunit alpha-2; cytokine, receptor, decoy, decoy receptor; HET: NAG, MLY; 3.05A {Homo sapiens}
3361 Probab=54.78 E-value=10 Score=33.26 Aligned_cols=18 Identities=11% Similarity=0.165 Sum_probs=10.5 Template_Neff=12.600
3362
3363 Q sp|Q9BYF1|ACE2 670 VRVANLKPRISFNFFVTA 687 (805)
3364 Q Consensus 670 vrvanlkprisfnffvta 687 (805)
3365 ..+.+|+|.-.+.|-|.+
3366 T Consensus 293 ~~~~~L~~~~~Y~~~V~a 310 (380)
3367 T 3LB6_C 293 YTLKTTNETRQLCFVVRS 310 (380)
3368 T ss_pred EEEecCCCCceEEEEEEE
3369 Confidence 445566666666665554
3370
3371
3372 No 65
3373 >3LB6_D Interleukin-13, Interleukin-13 receptor subunit alpha-2; cytokine, receptor, decoy, decoy receptor; HET: NAG; 3.05A {Homo sapiens}
3374 Probab=54.78 E-value=10 Score=33.26 Aligned_cols=18 Identities=11% Similarity=0.165 Sum_probs=7.8 Template_Neff=12.600
3375
3376 Q sp|Q9BYF1|ACE2 670 VRVANLKPRISFNFFVTA 687 (805)
3377 Q Consensus 670 vrvanlkprisfnffvta 687 (805)
3378 ..+.+|+|.-.+.|-|.+
3379 T Consensus 293 ~~~~~L~~~~~Y~~~V~a 310 (380)
3380 T 3LB6_D 293 YTLKTTNETRQLCFVVRS 310 (380)
3381 T ss_dssp EEECC----CCEEEEEEE
3382 T ss_pred EEEecCCCCceEEEEEEE
3383 Confidence 445566666666665554
3384
3385
3386 No 66
3387 >6FGB_A IgG receptor FcRn large subunit; FcRn, rozanolixizumab, ECD, Fab, immune; 2.9A {Homo sapiens}
3388 Probab=49.49 E-value=14 Score=35.50 Aligned_cols=10 Identities=10% Similarity=-0.157 Sum_probs=4.5 Template_Neff=10.000
3389
3390 Q sp|Q9BYF1|ACE2 776 SGENPYASID 785 (805)
3391 Q Consensus 776 sgenpyasid 785 (805)
3392 +..+++.+++
3393 T Consensus 311 ~~~~~~~~~~ 320 (342)
3394 T 6FGB_A 311 SLRGDDTGVL 320 (342)
3395 T ss_pred cCCCCCCCCc
3396 Confidence 3344555443
3397
3398
3399 No 67
3400 >4NKQ_B Cytokine receptor common subunit beta; GM-CSF, receptor complex, dodecamer, Disease; HET: NAG; 3.301A {Homo sapiens}
3401 Probab=46.89 E-value=16 Score=32.21 Aligned_cols=18 Identities=17% Similarity=0.263 Sum_probs=10.6 Template_Neff=11.700
3402
3403 Q sp|Q9BYF1|ACE2 670 VRVANLKPRISFNFFVTA 687 (805)
3404 Q Consensus 670 vrvanlkprisfnffvta 687 (805)
3405 ..+.+|+|...+.|-|.+
3406 T Consensus 186 ~~l~~L~p~t~Y~~~V~a 203 (305)
3407 T 4NKQ_B 186 YNFPSSEPRAKHSVKIRA 203 (305)
3408 T ss_pred EEccCCCCCCcEEEEEEE
3409 Confidence 345566666666665554
3410
3411
3412 No 68
3413 >6JXR_g T-cell surface glycoprotein CD3 zeta; IMMUNE SYSTEM;{Homo sapiens}
3414 Probab=43.82 E-value=20 Score=29.72 Aligned_cols=10 Identities=10% Similarity=0.408 Sum_probs=4.0 Template_Neff=11.300
3415
3416 Q sp|Q9BYF1|ACE2 743 LIVFGVVMGV 752 (805)
3417 Q Consensus 743 livfgvvmgv 752 (805)
3418 .|++|++.++
3419 T Consensus 117 ~i~~~~~~~~ 126 (182)
3420 T 6JXR_g 117 GFLFAEIVSI 126 (182)
3421 T ss_pred HHHHHHHHHH
3422 Confidence 3444443333
3423
3424
3425 No 69
3426 >5EH6_A Glycophorin-A; Receptor, lipidic cubic phase, peptides; 1.918A {Homo sapiens}
3427 Probab=43.27 E-value=20 Score=28.46 Aligned_cols=24 Identities=58% Similarity=1.035 Sum_probs=18.2 Template_Neff=2.200
3428
3429 Q sp|Q9BYF1|ACE2 741 IWLIVFGVVMGVIVVGIVILIFTGIR 766 (805)
3430 Q Consensus 741 iwlivfgvvmgvivvgiviliftgir 766 (805)
3431 |.+|+|||..|| +|.++||-..||
3432 T Consensus 4 I~lII~~vmagv--ig~ILlI~y~I~ 27 (30)
3433 T 5EH6_A 4 ITLIIFGVIAGV--IGTILLISYGIR 27 (30)
3434 T ss_dssp HHHHHHHHHHHH--HHHHHHHHHHHH
3435 T ss_pred HHHHHHHHHHHH--HHHHHHHHHHHH
3436 Confidence 778999999987 466666666665
3437
3438
3439 No 70
3440 >5EH4_C Glycophorin-A; Receptor, lipidic cubic phase, peptides; HET: SCH, OLB; 2.81A {Homo sapiens}
3441 Probab=43.27 E-value=20 Score=28.46 Aligned_cols=24 Identities=58% Similarity=1.035 Sum_probs=18.2 Template_Neff=2.200
3442
3443 Q sp|Q9BYF1|ACE2 741 IWLIVFGVVMGVIVVGIVILIFTGIR 766 (805)
3444 Q Consensus 741 iwlivfgvvmgvivvgiviliftgir 766 (805)
3445 |.+|+|||..|| +|.++||-..||
3446 T Consensus 4 I~lII~~vmagv--ig~ILlI~y~I~ 27 (30)
3447 T 5EH4_C 4 ITLIIFGVIAGV--IGTILLISYGIR 27 (30)
3448 T ss_dssp HHHHHHHHHHHH--HHHHHHHHHHHH
3449 T ss_pred HHHHHHHHHHHH--HHHHHHHHHHHH
3450 Confidence 778999999987 466666666665
3451
3452
3453 No 71
3454 >2XQ2_A SODIUM/GLUCOSE COTRANSPORTER; TRANSPORT PROTEIN, INVERTED REPEATS, LEUT-FOLD; HET: PEG; 2.73A {VIBRIO PARAHAEMOLYTICUS}
3455 Probab=39.81 E-value=25 Score=38.03 Aligned_cols=33 Identities=45% Similarity=0.708 Sum_probs=25.2 Template_Neff=8.700
3456
3457 Q sp|Q9BYF1|ACE2 739 VSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNK 773 (805)
3458 Q Consensus 739 vsiwlivfgvvmgvivvgiviliftgirdrkkknk 773 (805)
3459 .-||+|+|||..||| |++.+|-.+||.-.||+.
3460 T Consensus 548 ~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~ 580 (593)
3461 T 2XQ2_A 548 AEITLIIFGVMAGVI--GTILLISYGIKKLIKASY 580 (593)
3462 T ss_pred HHHHHHHHHHHHHHH--HHHHHHHHHHHHHhhcCC
3463 Confidence 346999999998865 677788888887666653
3464
3465
3466 No 72
3467 >2RDD_B Acriflavine resistance protein B, UPF0092; DRUG RESISTANCE, MULTIDRUG EFFLUX, TRANSPORTER; HET: AIC; 3.5A {Escherichia coli}
3468 Probab=39.22 E-value=26 Score=26.11 Aligned_cols=20 Identities=25% Similarity=0.323 Sum_probs=11.5 Template_Neff=6.900
3469
3470 Q sp|Q9BYF1|ACE2 756 GIVILIFTGIRDRKKKNKAR 775 (805)
3471 Q Consensus 756 giviliftgirdrkkknkar 775 (805)
3472 .++++.|.-+|..||+.|++
3473 T Consensus 12 ~~~~~~~~~~rpqkK~~k~~ 31 (37)
3474 T 2RDD_B 12 FGLIFYFMILRPQQKRTKEH 31 (37)
3475 T ss_dssp HHHHHHHHTHHHHHHHHHHH
3476 T ss_pred HHHHHHHHHHCHHHHHHHHH
3477 Confidence 34445555667766666554
3478
3479
3480 No 73
3481 >6CPL_A HLA class II histocompatibility antigen; IMMUNE RECEPTOR, IMMUNE SYSTEM; HET: NAG, SO4; 2.45A {Homo sapiens}
3482 Probab=39.13 E-value=26 Score=31.32 Aligned_cols=8 Identities=38% Similarity=0.904 Sum_probs=4.3 Template_Neff=10.400
3483
3484 Q sp|Q9BYF1|ACE2 591 LFTWLKDQ 598 (805)
3485 Q Consensus 591 lftwlkdq 598 (805)
3486 -.+|.++.
3487 T Consensus 118 ~v~W~~~~ 125 (229)
3488 T 6CPL_A 118 NVTWLRNG 125 (229)
3489 T ss_pred EEEEEECC
3490 Confidence 45666554
3491
3492
3493 No 74
3494 >6EJ2_A Beta-secretase 1 (E.C.3.4.23.46); BACE1, protease, Alzheimer, PEPTIDE BINDING; HET: B7E; 1.46A {Homo sapiens}
3495 Probab=38.02 E-value=28 Score=35.18 Aligned_cols=15 Identities=7% Similarity=0.138 Sum_probs=0.0 Template_Neff=10.200
3496
3497 Q sp|Q9BYF1|ACE2 736 QPPVSIWLIVFGVVM 750 (805)
3498 Q Consensus 736 qppvsiwlivfgvvm 750 (805)
3499 ....++..|+.++|-
3500 T Consensus 452 ~~~~~~~~ivg~~vg 466 (501)
3501 T 6EJ2_A 452 ESTLMTIAYVMAAIC 466 (501)
3502 T ss_dssp ---------------
3503 T ss_pred CCcchHHHHHHHHHH
3504 Confidence 334444444444333
3505
3506
3507 No 75
3508 >6ENY_F Beta-2-microglobulin, Tapasin, Protein disulfide-isomerase A3; adaptive immunity, antigen processing, chaperone; HET: NAG, MAN, BGC; 5.8A {Homo sapiens}
3509 Probab=37.88 E-value=28 Score=33.91 Aligned_cols=6 Identities=50% Similarity=1.359 Sum_probs=2.8 Template_Neff=9.700
3510
3511 Q sp|Q9BYF1|ACE2 592 FTWLKD 597 (805)
3512 Q Consensus 592 ftwlkd 597 (805)
3513 .+|.++
3514 T Consensus 215 v~W~~~ 220 (341)
3515 T 6ENY_F 215 LTWQRD 220 (341)
3516 T ss_dssp EEEEET
3517 T ss_pred EEEEeC
3518 Confidence 445444
3519
3520
3521 No 76
3522 >5XTH_0 NADH dehydrogenase [ubiquinone] flavoprotein 1; Homo sapiens, Oxidoreductase, Respiratory, Supercomplex; HET: PEE, CDL, HEA, HEC, FES, PLX, 8Q1, HEM, NDP, SF4, FMN; 3.9A {Homo sapiens}
3523 Probab=37.10 E-value=29 Score=33.41 Aligned_cols=32 Identities=22% Similarity=0.281 Sum_probs=22.9 Template_Neff=5.900
3524
3525 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFT 763 (805)
3526 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgivilift 763 (805)
3527 ||+-++|..-|-.|+|.++++|.+++++.++.
3528 T Consensus 65 ~~e~~~p~g~wK~v~~~v~~~~~~s~~lf~~~ 96 (144)
3529 T 5XTH_0 65 FAEMNRSTNEWKTVVGAAMFFIGFTALLLIWE 96 (144)
3530 T ss_pred cccccCCCchHHHHHHHHHHHHHHHHHHHHHH
3531 Confidence 45667888889888888887776666555543
3532
3533
3534 No 77
3535 >5B1A_D Cytochrome c oxidase subunit 1; Oxidoreductase, Proton pump, Heme, Respiratory; HET: FME, CDL, TGL, HEA, PGV, CHD, PSC, PEK, DMU, TPO, SAC; 1.5A {Bos taurus}
3536 Probab=33.75 E-value=36 Score=33.09 Aligned_cols=32 Identities=22% Similarity=0.281 Sum_probs=22.9 Template_Neff=5.700
3537
3538 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFT 763 (805)
3539 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgivilift 763 (805)
3540 ||+-++|...|-.|||.+++++.+++++.++.
3541 T Consensus 68 gp~~~~p~~~~k~v~~~~~~~~~~s~~l~~~~ 99 (147)
3542 T 5B1A_D 68 FAEMNRSTNEWKTVVGAAMFFIGFTALLLIWE 99 (147)
3543 T ss_dssp HHHHTCCCSHHHHHHHHHHHHHHHHHHHHHHH
3544 T ss_pred cccccCCCchHHHHHHHHHHHHHHHHHHHHHH
3545 Confidence 55667888889888888877776666555543
3546
3547
3548 No 78
3549 >6PY2_A HLA class II histocompatibility antigen; HLA, MHC, TCR, Gluten, IMMUNE; HET: NAG, GOL; 2.82543430029A {Homo sapiens}
3550 Probab=33.31 E-value=37 Score=31.36 Aligned_cols=9 Identities=33% Similarity=0.785 Sum_probs=5.7 Template_Neff=10.000
3551
3552 Q sp|Q9BYF1|ACE2 591 LFTWLKDQN 599 (805)
3553 Q Consensus 591 lftwlkdqn 599 (805)
3554 -++|.++..
3555 T Consensus 143 ~v~W~~~g~ 151 (254)
3556 T 6PY2_A 143 NITWLSNGH 151 (254)
3557 T ss_dssp EEEEEETTE
3558 T ss_pred EEEEEECCE
3559 Confidence 477777643
3560
3561
3562 No 79
3563 >6GJE_A Protein amnionless, Cubilin; receptor, vitamin B12, cubilin, amnionless; 2.3A {Homo sapiens}
3564 Probab=33.17 E-value=37 Score=37.81 Aligned_cols=18 Identities=28% Similarity=0.311 Sum_probs=0.0 Template_Neff=6.100
3565
3566 Q sp|Q9BYF1|ACE2 783 SIDISKGENNPGFQNTDD 800 (805)
3567 Q Consensus 783 sidiskgennpgfqntdd 800 (805)
3568 .-...+|-.||-|....+
3569 T Consensus 399 ~~~~~~gf~NP~fd~~~~ 416 (453)
3570 T 6GJE_A 399 PAGAPLGFRNPVFDVTAS 416 (453)
3571 T ss_dssp ------------------
3572 T ss_pred CCCCCCCcCCccccCCCC
3573 Confidence 556778889998877644
3574
3575
3576 No 80
3577 >6C13_A Protocadherin-15; PCDH15, LHFPL5, protocadherin, tip link; HET: MAN, BMA, NAG;{Mus musculus}
3578 Probab=32.87 E-value=38 Score=34.96 Aligned_cols=13 Identities=31% Similarity=0.317 Sum_probs=6.8 Template_Neff=10.700
3579
3580 Q sp|Q9BYF1|ACE2 693 DIIPRTEVEKAIR 705 (805)
3581 Q Consensus 693 diiprtevekair 705 (805)
3582 .++.+.++.+.+.
3583 T Consensus 508 ~i~~~~~~~~~l~ 520 (660)
3584 T 6C13_A 508 RAIDRNELFKFLD 520 (660)
3585 T ss_dssp EECCHHHHHHHHH
3586 T ss_pred eEecHHHHHHHHh
3587 Confidence 3555555555544
3588
3589
3590 No 81
3591 >5DJQ_P Cbb3-type cytochrome c oxidase subunit; oxidoreductase, cbb3-cytochrome c oxidase, Pseudomonas_stutzeri; HET: PO4, HEC, FC6, HEM; 3.2A {Pseudomonas stutzeri}
3592 Probab=32.78 E-value=38 Score=27.68 Aligned_cols=24 Identities=42% Similarity=0.845 Sum_probs=13.0 Template_Neff=3.100
3593
3594 Q sp|Q9BYF1|ACE2 748 VVMGVIVVGIVILIFTGI-----RDRKKK 771 (805)
3595 Q Consensus 748 vvmgvivvgiviliftgi-----rdrkkk 771 (805)
3596 |+.|+++||..++.|.|. ||.+||
3597 T Consensus 7 ViaGi~tVglm~~Ff~G~g~FIwkD~~k~ 35 (36)
3598 T 5DJQ_P 7 VLAGVVTVGLMVAFLAGFGYFIWRDAHKK 35 (36)
3599 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHC------
3600 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhHhhhhc
3601 Confidence 566777788877777764 555554
3602
3603
3604 No 82
3605 >1CD1_A CD1; CD1, IMMUNOLOGY, MHC, TCR, GLYCOPROTEIN; 2.67A {Mus musculus} SCOP: b.1.1.2, d.19.1.1
3606 Probab=32.51 E-value=39 Score=31.77 Aligned_cols=7 Identities=14% Similarity=0.961 Sum_probs=3.3 Template_Neff=10.400
3607
3608 Q sp|Q9BYF1|ACE2 592 FTWLKDQ 598 (805)
3609 Q Consensus 592 ftwlkdq 598 (805)
3610 .+|+++.
3611 T Consensus 217 v~W~~~g 223 (315)
3612 T 1CD1_A 217 VMWMRGD 223 (315)
3613 T ss_dssp EEEEETT
3614 T ss_pred EEEEECC
3615 Confidence 4555443
3616
3617
3618 No 83
3619 >6AT5_A HLA class I histocompatibility antigen; Human Leukocyte Antigen, Major histocompatibility; 1.5A {Homo sapiens}
3620 Probab=29.91 E-value=46 Score=33.01 Aligned_cols=8 Identities=38% Similarity=0.924 Sum_probs=4.5 Template_Neff=9.500
3621
3622 Q sp|Q9BYF1|ACE2 591 LFTWLKDQ 598 (805)
3623 Q Consensus 591 lftwlkdq 598 (805)
3624 -.+|.++.
3625 T Consensus 238 ~v~W~~~g 245 (362)
3626 T 6AT5_A 238 TLTWQRDG 245 (362)
3627 T ss_dssp EEEEEETT
3628 T ss_pred EEEEEeCC
3629 Confidence 35666653
3630
3631
3632 No 84
3633 >4JIX_A Uncharacterized protein MJ0123; Hydrolase, Metallopeptidase Zymogen, Minigluzincin; HET: GOL, SO4; 2.0A {Methanocaldococcus jannaschii}
3634 Probab=28.17 E-value=51 Score=27.66 Aligned_cols=41 Identities=20% Similarity=0.211 Sum_probs=24.4 Template_Neff=9.100
3635
3636 Q sp|Q9BYF1|ACE2 371 TAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSI 421 (805)
3637 Q Consensus 371 tahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlksi 421 (805)
3638 +--|||+|+... ..+-+..|...+..++.-...--+.|+..
3639 T Consensus 68 vi~HEl~H~~~~----------~~~H~~~f~~~~~~~~p~~~~~~~~l~~~ 108 (112)
3640 T 4JIX_A 68 IILHELIHFKIK----------SINHGIKFENELRNYFSKNECDEIELKII 108 (112)
3641 T ss_dssp HHHHHHHHHHHT----------CSSCSHHHHHHHTTTCCHHHHHHHHHHHH
3642 T ss_pred HHHHHHHHHHhh----------cccccHHHHHHHHHHcccchhhHHHHHHH
3643 Confidence 557999999762 23334567777766665544444444443
3644
3645
3646 No 85
3647 >4JIX_B Projannalysin; Hydrolase, Metallopeptidase Zymogen, Minigluzincin; HET: SO4, GOL; 2.0A {Methanocaldococcus jannaschii}
3648 Probab=28.17 E-value=51 Score=27.66 Aligned_cols=41 Identities=20% Similarity=0.211 Sum_probs=24.4 Template_Neff=9.100
3649
3650 Q sp|Q9BYF1|ACE2 371 TAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSI 421 (805)
3651 Q Consensus 371 tahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlksi 421 (805)
3652 +--|||+|+... ..+-+..|...+..++.-...--+.|+..
3653 T Consensus 68 vi~HEl~H~~~~----------~~~H~~~f~~~~~~~~p~~~~~~~~l~~~ 108 (112)
3654 T 4JIX_B 68 IILHELIHFKIK----------SINHGIKFENELRNYFSKNECDEIELKII 108 (112)
3655 T ss_dssp HHHHHHHHHHHT----------CSCCSHHHHHHHTTTCCHHHHHHHHHHHH
3656 T ss_pred HHHHHHHHHHhh----------cccccHHHHHHHHHHcccchhhHHHHHHH
3657 Confidence 557999999762 23334567777766665544444444443
3658
3659
3660 No 86
3661 >6IDF_E Nicastrin, Presenilin-1 (E.C.3.4.23.-), Gamma-secretase subunit; complex, MEMBRANE PROTEIN; HET: BMA, NAG, CLR, PC1;{Homo sapiens}
3662 Probab=27.63 E-value=53 Score=31.80 Aligned_cols=16 Identities=6% Similarity=0.139 Sum_probs=7.4 Template_Neff=5.100
3663
3664 Q sp|Q9BYF1|ACE2 733 PPNQPPVSIWLIVFGV 748 (805)
3665 Q Consensus 733 ppnqppvsiwlivfgv 748 (805)
3666 ||..++...|+++.|+
3667 T Consensus 9 ~~~~~~~~~~~v~i~~ 24 (129)
3668 T 6IDF_E 9 CPPPAQLHFMYVAAAA 24 (129)
3669 T ss_dssp SCCCCSSSHHHHHHTH
3670 T ss_pred CCCChhhHHHHHHHHH
3671 Confidence 3333344456555444
3672
3673
3674 No 87
3675 >6IVA_D Oxaloacetate decarboxylase beta chain (E.C.7.2.4.2); membrane protein, decarboxylase sodium pump; 4.403A {Salmonella enterica I}
3676 Probab=26.48 E-value=58 Score=29.72 Aligned_cols=27 Identities=11% Similarity=0.212 Sum_probs=12.5 Template_Neff=6.300
3677
3678 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIFTG 764 (805)
3679 Q Consensus 738 pvsiwlivfgvvmgvivvgiviliftg 764 (805)
3680 .+.+-++.+|+|+.++++.++++.+.+
3681 T Consensus 31 ~l~i~iiGm~vVF~vLilL~lvi~l~~ 57 (104)
3682 T 6IVA_D 31 GFTLMFLGMGFVLAFLFLLIFAIRGMS 57 (104)
3683 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHH
3684 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHH
3685 Confidence 344445555555555444444333333
3686
3687
3688 No 88
3689 >6IWW_B Oxaloacetate decarboxylase beta chain (E.C.7.2.4.2); membrane protein, sodium pump, decarboxylase; HET: LMT; 3.9A {Salmonella enterica subsp. enterica}
3690 Probab=26.48 E-value=58 Score=29.72 Aligned_cols=27 Identities=11% Similarity=0.212 Sum_probs=12.5 Template_Neff=6.300
3691
3692 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIFTG 764 (805)
3693 Q Consensus 738 pvsiwlivfgvvmgvivvgiviliftg 764 (805)
3694 .+.+-++.+|+|+.++++.++++.+.+
3695 T Consensus 31 ~l~i~iiGm~vVF~vLilL~lvi~l~~ 57 (104)
3696 T 6IWW_B 31 GFTLMFLGMGFVLAFLFLLIFAIRGMS 57 (104)
3697 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHH
3698 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHH
3699 Confidence 344445555555555444444333333
3700
3701
3702 No 89
3703 >6BRJ_A Epithelial discoidin domain-containing receptor 1; Kinase, Inhibitor, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR; HET: VX6; 2.231A {Homo sapiens}
3704 Probab=25.27 E-value=63 Score=37.06 Aligned_cols=7 Identities=57% Similarity=1.545 Sum_probs=0.0 Template_Neff=8.500
3705
3706 Q sp|Q9BYF1|ACE2 602 SFVGWST 608 (805)
3707 Q Consensus 602 sfvgwst 608 (805)
3708 .||||+.
3709 T Consensus 254 ~~~~~~~ 260 (876)
3710 T 6BRJ_A 254 DYVGWSN 260 (876)
3711 T ss_dssp -------
3712 T ss_pred Ceeeeec
3713 Confidence 4555543
3714
3715
3716 No 90
3717 >3EHB_B Cytochrome c oxidase subunit 1-beta; proton pumping, water chain, electron; HET: LDA, LMT, HEA; 2.32A {Paracoccus denitrificans} SCOP: f.17.2.1, b.6.1.2
3718 Probab=25.21 E-value=63 Score=33.82 Aligned_cols=47 Identities=15% Similarity=0.255 Sum_probs=20.2 Template_Neff=6.800
3719
3720 Q sp|Q9BYF1|ACE2 725 LGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3721 Q Consensus 725 lgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3722 +|.|+..+|..+.-...+-.++.+++.+.++..+++++.-+|-|+++
3723 T Consensus 47 ~~~~~~as~~a~~i~~L~~~~l~i~~~I~v~V~~ll~~~i~ryr~~~ 93 (298)
3724 T 3EHB_B 47 MNFQPASSPLAHDQQWLDHFVLYIITAVTIFVCLLLLICIVRFNRRA 93 (298)
3725 T ss_pred cCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchhcC
3726 Confidence 55666665555544444433333322222222223334444555443
3727
3728
3729 No 91
3730 >6PY2_B HLA class II histocompatibility antigen; HLA, MHC, TCR, Gluten, IMMUNE; HET: NAG, GOL; 2.82543430029A {Homo sapiens}
3731 Probab=24.26 E-value=67 Score=30.09 Aligned_cols=11 Identities=36% Similarity=0.760 Sum_probs=0.0 Template_Neff=9.800
3732
3733 Q sp|Q9BYF1|ACE2 745 VFGVVMGVIVV 755 (805)
3734 Q Consensus 745 vfgvvmgvivv 755 (805)
3735 ++|++++++++
3736 T Consensus 235 ~~~~~~~l~~~ 245 (261)
3737 T 6PY2_B 235 IGGFVLGLIFL 245 (261)
3738 T ss_dssp -----------
3739 T ss_pred HHHHHHHHHHH
3740 Confidence 44555555444
3741
3742
3743 No 92
3744 >1Q5B_C EP-cadherin, ectodomain; CADHERIN TRANS INTERACTION ; HET: NDG, NAG, CA; 30.0A {Mus musculus} SCOP: i.20.1.1
3745 Probab=24.14 E-value=68 Score=34.98 Aligned_cols=12 Identities=25% Similarity=0.495 Sum_probs=3.1 Template_Neff=10.300
3746
3747 Q sp|Q9BYF1|ACE2 155 SLDYNERLWAWE 166 (805)
3748 Q Consensus 155 sldynerlwawe 166 (805)
3749 .+....|-|.|.
3750 T Consensus 149 ~~~r~~~~~~~~ 160 (880)
3751 T 1Q5B_C 149 GLKRKKRDWVIP 160 (880)
3752 T ss_dssp -------CCBCC
3753 T ss_pred CCccCCcceeCC
3754 Confidence 344455666654
3755
3756
3757 No 93
3758 >2JO1_A Phospholemman; FXYD1, Na,K-ATPase, Micelle, HYDROLASE REGULATOR; NMR {Homo sapiens}
3759 Probab=23.89 E-value=69 Score=29.34 Aligned_cols=30 Identities=33% Similarity=0.345 Sum_probs=11.7 Template_Neff=3.400
3760
3761 Q sp|Q9BYF1|ACE2 747 GVVMGVIVVGIVILIFTGIRDRKKKNKARS 776 (805)
3762 Q Consensus 747 gvvmgvivvgiviliftgirdrkkknkars 776 (805)
3763 |++++++...+.|+|.++-|-|-+.|+.++
3764 T Consensus 20 GLi~A~vLfi~GIliils~kckC~~~q~~~ 49 (72)
3765 T 2JO1_A 20 GLVIAGILFILGILIVLSRRCRCKFNQQQR 49 (72)
3766 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCTTTS
3767 T ss_pred HHHHHHHHHHHHHHHHHhccccccCCcCCC
3768 Confidence 444333333333333334444444444333
3769
3770
3771 No 94
3772 >2KV5_A Putative uncharacterized protein RNAI; toxin-antitoxin, bacterial, toxin; NMR {N/A}
3773 Probab=23.51 E-value=71 Score=25.42 Aligned_cols=27 Identities=22% Similarity=0.514 Sum_probs=19.0 Template_Neff=4.000
3774
3775 Q sp|Q9BYF1|ACE2 745 VFGVVMGVIVVGIVILIFTGIRD-RKKK 771 (805)
3776 Q Consensus 745 vfgvvmgvivvgiviliftgird-rkkk 771 (805)
3777 +|-.+++-|+||+++-+|+-.-| |.+|
3778 T Consensus 4 if~~IiapiivG~vv~lf~~WL~~r~~k 31 (33)
3779 T 2KV5_A 4 LMSLVIAPIFVGLVLEMISRVLDEEDDS 31 (33)
3780 T ss_dssp THHHHHHHHHHHHHHHHHHHHTTCCCCC
3781 T ss_pred HHHHhHHHHHHHHHHHHHHHHHHhcccc
3782 Confidence 45567788889999988886544 4443
3783
3784
3785 No 95
3786 >6BSD_A Epithelial discoidin domain-containing receptor 1; Kinase, Inhibitor, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR; HET: 1N1; 2.606A {Homo sapiens}
3787 Probab=23.31 E-value=72 Score=36.61 Aligned_cols=7 Identities=57% Similarity=1.545 Sum_probs=3.5 Template_Neff=8.500
3788
3789 Q sp|Q9BYF1|ACE2 602 SFVGWST 608 (805)
3790 Q Consensus 602 sfvgwst 608 (805)
3791 .||||+.
3792 T Consensus 254 ~~~~~~~ 260 (876)
3793 T 6BSD_A 254 DYVGWSN 260 (876)
3794 T ss_pred Ceeeeec
3795 Confidence 4555543
3796
3797
3798 No 96
3799 >6KOE_F AA3-600 quinol oxidase subunit I; Menaquinol oxidase, Complex, Proton pumping; HET: HQO, HEA; 3.75A {Bacillus subtilis}
3800 Probab=22.61 E-value=76 Score=33.75 Aligned_cols=40 Identities=20% Similarity=0.404 Sum_probs=17.8 Template_Neff=6.100
3801
3802 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3803 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3804 ||..+.-..++++.+++.+.|+++.++++++..+|-|+++
3805 T Consensus 11 gp~a~~~~~l~~~~~~~~l~i~v~V~~l~~~~~~rYR~~~ 50 (296)
3806 T 6KOE_F 11 GPVAEQQSDLILLSIGFMLFIVGVVFVLFTIILVKYRDRK 50 (296)
3807 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchhcC
3808 Confidence 4444333333444444444443333444444556655554
3809
3810
3811 No 97
3812 >6KOB_B AA3-600 quinol oxidase subunit I; Menaquinol oxidase, Complex, Proton pumping; HET: MQ7, HEA; 3.6A {Bacillus subtilis}
3813 Probab=22.61 E-value=76 Score=33.75 Aligned_cols=40 Identities=20% Similarity=0.404 Sum_probs=15.7 Template_Neff=6.100
3814
3815 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3816 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3817 ||..+.-..++++.+++.+.|+++.++++++..+|-|+++
3818 T Consensus 11 gp~a~~~~~l~~~~~~~~l~i~v~V~~l~~~~~~rYR~~~ 50 (296)
3819 T 6KOB_B 11 GPVAEQQSDLILLSIGFMLFIVGVVFVLFTIILVKYRDRK 50 (296)
3820 T ss_dssp -----CTTHHHHHHHHHHHHHHHHHHHHTTTSSSSSSCCC
3821 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchhcC
3822 Confidence 4444333333444444444443333444444556655554
3823
3824
3825 No 98
3826 >1Q90_G Apocytochrome f, Cytochrome b6, Cytochrome; MEMBRANE PROTEIN COMPLEX, PHOTOSYNTHESIS, ELECTRON; HET: LFA, CLA, BCR, SQD, LMG, HEM, TDS; 3.1A {Chlamydomonas reinhardtii} SCOP: f.23.26.1
3827 Probab=22.36 E-value=78 Score=26.34 Aligned_cols=29 Identities=24% Similarity=0.430 Sum_probs=22.3 Template_Neff=2.400
3828
3829 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVIVVGIVILIFTGIRDRKKKN 772 (805)
3830 Q Consensus 744 ivfgvvmgvivvgiviliftgirdrkkkn 772 (805)
3831 +.+|+|.|.|.|.++-|.++....-++.+
3832 T Consensus 5 lL~GIVlGli~iTlaGLfv~AY~QyrRg~ 33 (37)
3833 T 1Q90_G 5 LLCGIVLGLVPVTIAGLFVTAYLQYLRGD 33 (37)
3834 T ss_pred hHHHHHHHhHHHHHHHHHHHHHHHHHhcc
3835 Confidence 57899999999998888888765544433
3836
3837
3838 No 99
3839 >2GSM_B Cytochrome c oxidase subunit 1; transmembrane protein complex, OXIDOREDUCTASE; HET: TRD, DMU, HEA; 2.0A {Rhodobacter sphaeroides} SCOP: f.17.2.1, b.6.1.2
3840 Probab=21.90 E-value=80 Score=31.85 Aligned_cols=6 Identities=67% Similarity=1.121 Sum_probs=2.5 Template_Neff=7.600
3841
3842 Q sp|Q9BYF1|ACE2 721 SLEFLG 726 (805)
3843 Q Consensus 721 sleflg 726 (805)
3844 ||++.|
3845 T Consensus 4 ~~~~~~ 9 (262)
3846 T 2GSM_B 4 SLEIIG 9 (262)
3847 T ss_dssp -CCEEE
3848 T ss_pred ccccCC
3849 Confidence 455544
3850
3851
3852 No 100
3853 >3HB3_B Cytochrome c oxidase subunit 1-beta; Electron transfer, Proton transfer, Proton; HET: HEA, LDA, LMT; 2.25A {Paracoccus denitrificans}
3854 Probab=21.53 E-value=83 Score=32.92 Aligned_cols=47 Identities=15% Similarity=0.280 Sum_probs=18.3 Template_Neff=6.900
3855
3856 Q sp|Q9BYF1|ACE2 725 LGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIV-ILIFTGIRDRKKKN 772 (805)
3857 Q Consensus 725 lgiqptlgppnqppvsiwlivfgvvmgvivvgiv-iliftgirdrkkkn 772 (805)
3858 ++.|+..+|-.+.-...+-+++++. .+|++++. ++++.-+|-|++++
3859 T Consensus 47 ~~~~~~aS~~a~~i~~L~~~~~~i~-~~Ifv~V~~ll~~~i~ryr~~~~ 94 (298)
3860 T 3HB3_B 47 MNFQPASSPLAHDQQWLDHFVLYII-TAVTIFVCLLLLICIVRFNRRAN 94 (298)
3861 T ss_dssp CSCSCCCSHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHSBTTTS
3862 T ss_pred CCCCCCCCHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHccccCC
3863 Confidence 3444444444443333333333332 22222222 23333355555443
3864
3865
3866 No 101
3867 >5X5V_A GD; herpes simplex virus, pseudorabies virus; 1.5A {Suid herpesvirus 1}
3868 Probab=20.11 E-value=93 Score=35.59 Aligned_cols=28 Identities=32% Similarity=0.647 Sum_probs=0.0 Template_Neff=3.400
3869
3870 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGVIVVGIVILIFTGIRDRK 769 (805)
3871 Q Consensus 742 wlivfgvvmgvivvgiviliftgirdrk 769 (805)
3872 ..+-.|+.||.|+||+.+.||..+|..|
3873 T Consensus 355 v~vgvg~~~~~~~~~~~~~~~~~~~~~~ 382 (402)
3874 T 5X5V_A 355 VIVGTGTAMGALLVGVCVYIFFRLRGAK 382 (402)
3875 T ss_dssp ----------------------------
3876 T ss_pred eehhHHHHHHHHHHHHHHHHHHHccccc
3877 Confidence 3456799999999999999998877654
3878
3879