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comparison test-data/model/hhr.ffdata @ 0:64cb5fab9c60 draft

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"planemo upload commit 6158473dbced09024b0a805a7df2c93d47705d87"
author guerler
date Tue, 23 Mar 2021 13:57:37 +0000
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-1:000000000000 0:64cb5fab9c60
1 Query sp|Q9BYF1|ACE2_HUMAN Angiotensin-converting enzyme 2 OS=Homo sapiens (Human) OX=9606 GN=ACE2 PE=1 SV=2
2 Match_columns 805
3 No_of_seqs 1 out of 1
4 Neff 1
5 Searched_HMMs 82491
6 Date Sat Oct 10 23:55:36 2020
7 Command hhsearch -e 0.001 -i /galaxy-repl/main/files/046/047/dataset_46047478.dat -d hhdb -o /galaxy-repl/main/files/046/091/dataset_46091622.dat
8
9 No Hit Prob E-value P-value Score SS Cols Query HMM Template HMM
10 1 6M18_B Sodium-dependent neutra 100.0 4E-194 5E-199 1504.8 0.0 804 2-805 3-814 (814)
11 2 1R42_A angiotensin I convertin 100.0 3.4E-78 4.2E-83 582.0 0.0 615 1-615 1-615 (615)
12 3 6LZG_A Angiotensin-converting 100.0 5.4E-74 6.6E-79 545.9 0.0 597 19-615 1-597 (597)
13 4 3D0I_B Crystal structure of sp 100.0 1.2E-73 1.5E-78 545.2 0.0 596 20-615 2-597 (597)
14 5 5AMB_A ANGIOTENSIN-CONVERTING 100.0 1.2E-69 1.5E-74 524.2 0.0 595 20-625 12-614 (629)
15 6 6H5W_A Angiotensin-converting 100.0 4.4E-61 5.4E-66 455.7 0.0 579 22-613 5-588 (591)
16 7 6S1Y_A Angiotensin-converting 100.0 4.6E-59 5.5E-64 450.3 0.0 579 21-610 11-600 (621)
17 8 4CA5_A ANGIOTENSIN-CONVERTING 100.0 3.9E-58 4.7E-63 435.5 0.0 578 22-612 5-587 (589)
18 9 5A2R_A ANGIOTENSIN-CONVERTING 100.0 2.8E-56 3.4E-61 425.1 0.0 579 22-611 5-594 (598)
19 10 4ASR_A ANGIOTENSIN-CONVERTING 100.0 2.9E-56 3.5E-61 426.4 0.0 578 22-611 6-595 (598)
20 11 4CA7_A ANGIOTENSIN-CONVERTING 100.0 3.2E-56 3.9E-61 426.0 0.0 578 22-611 6-595 (598)
21 12 2C6F_A ANGIOTENSIN-CONVERTING 100.0 2.3E-52 2.7E-57 400.7 0.0 579 22-611 14-599 (612)
22 13 5GIV_E Carboxypeptidase; M32 c 100.0 4.3E-52 5.2E-57 399.6 0.0 474 19-597 3-502 (503)
23 14 5GIV_F Carboxypeptidase; M32 c 100.0 4.3E-52 5.2E-57 399.6 0.0 474 19-597 3-502 (503)
24 15 3HQ2_B Bacillus subtilis M32 c 100.0 1.1E-47 1.3E-52 361.2 0.0 473 22-597 3-500 (501)
25 16 1K9X_B m32 carboxypeptidase; H 100.0 1.1E-46 1.3E-51 357.8 0.0 470 20-593 4-499 (499)
26 17 1KA2_A M32 carboxypeptidase; H 100.0 1.1E-46 1.3E-51 357.8 0.0 470 20-593 4-499 (499)
27 18 5E3X_A Thermostable carboxypep 100.0 2.4E-46 2.9E-51 356.7 0.0 456 27-597 2-486 (489)
28 19 3HOA_A Thermostable carboxypep 100.0 1.1E-45 1.3E-50 356.9 0.0 468 22-594 3-507 (509)
29 20 3DWC_B Metallocarboxypeptidase 100.0 2E-44 2.4E-49 343.9 0.0 459 23-593 3-501 (505)
30 21 5WVU_C Thermostable carboxypep 100.0 8.4E-44 1E-48 344.0 0.0 469 22-595 3-508 (510)
31 22 3SKS_A Putative Oligoendopepti 100.0 1.7E-38 2.1E-43 300.7 0.0 506 22-600 36-564 (567)
32 23 3AHN_A Oligopeptidase; HYDROLA 100.0 2.6E-38 3.2E-43 299.3 0.0 505 22-601 33-562 (564)
33 24 2QR4_A Peptidase M3B, oligoend 100.0 2E-33 2.4E-38 267.6 0.0 506 23-603 34-578 (587)
34 25 2O36_A Thimet oligopeptidase ( 99.9 5E-30 6.1E-35 254.5 0.0 518 26-588 47-660 (674)
35 26 3CE2_A Crystal structure of pu 99.9 1.1E-29 1.4E-34 244.3 0.0 507 23-601 67-609 (618)
36 27 2O3E_A Neurolysin (E.C.3.4.24. 99.9 9.4E-29 1.1E-33 246.4 0.0 515 31-588 68-676 (678)
37 28 5LV0_A Neurolysin, mitochondri 99.9 6.2E-28 7.6E-33 240.2 0.0 504 41-589 83-682 (686)
38 29 1S4B_P Thimet oligopeptidase ( 99.9 1.6E-27 2E-32 236.8 0.0 516 26-588 47-660 (674)
39 30 5L44_A K-26 dipeptidyl carboxy 99.8 4.9E-23 6E-28 205.4 0.0 512 28-589 76-681 (683)
40 31 5L43_B K-26 dipeptidyl carboxy 99.8 4.9E-23 6E-28 205.4 0.0 512 28-589 76-681 (683)
41 32 1Y79_1 Peptidyl-Dipeptidase Dc 99.4 4.5E-17 5.4E-22 163.2 0.0 501 41-588 70-676 (680)
42 33 4KA7_A Oligopeptidase A, short 99.4 5.8E-17 7.1E-22 163.7 0.0 407 144-589 239-706 (714)
43 34 2KNC_B Integrin alpha-IIb, Int 92.7 0.036 4.4E-07 45.3 0.0 31 733-763 2-32 (79)
44 35 2L8S_A Integrin alpha-1; Integ 87.6 0.29 3.5E-06 40.2 0.0 43 736-778 4-48 (54)
45 36 2N2A_B Receptor tyrosine-prote 86.5 0.38 4.6E-06 38.4 0.0 30 742-771 9-38 (58)
46 37 2KNC_A Integrin alpha-IIb, Int 85.7 0.45 5.4E-06 38.7 0.0 40 735-774 6-47 (54)
47 38 2M3E_A Integrin alpha-L; integ 85.4 0.48 5.8E-06 38.2 0.0 39 736-774 7-47 (50)
48 39 6J8H_C Sodium channel subunit 84.3 0.6 7.2E-06 37.2 0.0 8 591-598 64-71 (215)
49 40 2N9Y_B Integrin alpha-IIb, Int 84.0 0.63 7.7E-06 35.0 0.0 30 737-766 5-34 (43)
50 41 6JXR_n T-cell surface glycopro 83.4 0.7 8.5E-06 38.0 0.0 7 591-597 154-160 (291)
51 42 2K9J_A Integrin alpha-IIb ligh 83.0 0.74 9E-06 35.9 0.0 39 732-770 1-41 (42)
52 43 2N5S_A Epidermal growth factor 82.7 0.79 9.6E-06 34.0 0.0 10 744-753 8-17 (54)
53 44 4UM8_D INTEGRIN ALPHA-V, INTEG 80.8 1 1.3E-05 49.0 0.0 25 738-762 705-729 (788)
54 45 4UM8_B INTEGRIN ALPHA-V, INTEG 78.7 1.4 1.7E-05 48.1 0.0 25 738-762 705-729 (788)
55 46 1AFO_A GLYCOPHORIN A; INTEGRAL 75.9 1.9 2.3E-05 35.5 0.0 37 732-771 4-40 (40)
56 47 6A69_B Plasma membrane calcium 75.9 1.9 2.3E-05 35.7 0.0 15 742-756 224-238 (282)
57 48 6AGF_B Sodium channel protein 75.3 2 2.5E-05 35.7 0.0 22 773-795 192-213 (218)
58 49 6J8J_B Sodium channel subunit 75.3 2 2.5E-05 35.7 0.0 22 773-795 192-213 (218)
59 50 6C14_A Protocadherin-15, LHFPL 74.5 2.2 2.7E-05 40.6 0.0 23 738-760 238-260 (337)
60 51 6UJB_B Integrin alpha-V, Integ 73.3 2.5 3E-05 45.8 0.0 25 738-762 637-661 (727)
61 52 6UJA_B Integrin alpha-V, Integ 73.3 2.5 3E-05 45.8 0.0 25 738-762 637-661 (727)
62 53 2M20_A Epidermal growth factor 72.7 2.6 3.2E-05 32.9 0.0 10 744-753 5-14 (60)
63 54 5OR7_C Capsid protein, CMRF35- 72.6 2.7 3.2E-05 38.5 0.0 6 592-597 52-57 (330)
64 55 2MFR_A Insulin receptor (E.C.2 69.0 3.6 4.4E-05 33.9 0.0 38 740-779 15-52 (57)
65 56 4U0Q_B Plasmodium falciparum R 67.3 4.2 5.1E-05 33.8 0.0 13 744-756 211-223 (269)
66 57 5A2F_A CD166 ANTIGEN; CELL ADH 63.7 5.5 6.7E-05 38.7 0.0 11 589-599 442-452 (583)
67 58 2KLU_A T-cell surface glycopro 59.8 7.3 8.8E-05 30.3 0.0 9 744-752 12-20 (70)
68 59 6ENY_C Beta-2-microglobulin, T 58.0 8.2 9.9E-05 37.8 0.0 9 539-547 248-256 (428)
69 60 1S7Q_A H-2 class I histocompat 57.9 8.2 0.0001 37.5 0.0 11 742-752 285-295 (348)
70 61 1S7S_A H-2 class I histocompat 57.9 8.2 0.0001 37.5 0.0 11 742-752 285-295 (348)
71 62 2WY3_A MHC CLASS I POLYPEPTIDE 57.3 8.6 0.0001 35.8 0.0 9 591-599 214-222 (319)
72 63 6JXR_f T-cell surface glycopro 55.1 9.8 0.00012 32.9 0.0 14 741-754 130-143 (207)
73 64 3LB6_C Interleukin-13, Interle 54.8 10 0.00012 33.3 0.0 18 670-687 293-310 (380)
74 65 3LB6_D Interleukin-13, Interle 54.8 10 0.00012 33.3 0.0 18 670-687 293-310 (380)
75 66 6FGB_A IgG receptor FcRn large 49.5 14 0.00017 35.5 0.0 10 776-785 311-320 (342)
76 67 4NKQ_B Cytokine receptor commo 46.9 16 0.0002 32.2 0.0 18 670-687 186-203 (305)
77 68 6JXR_g T-cell surface glycopro 43.8 20 0.00024 29.7 0.0 10 743-752 117-126 (182)
78 69 5EH6_A Glycophorin-A; Receptor 43.3 20 0.00025 28.5 0.0 24 741-766 4-27 (30)
79 70 5EH4_C Glycophorin-A; Receptor 43.3 20 0.00025 28.5 0.0 24 741-766 4-27 (30)
80 71 2XQ2_A SODIUM/GLUCOSE COTRANSP 39.8 25 0.0003 38.0 0.0 33 739-773 548-580 (593)
81 72 2RDD_B Acriflavine resistance 39.2 26 0.00031 26.1 0.0 20 756-775 12-31 (37)
82 73 6CPL_A HLA class II histocompa 39.1 26 0.00031 31.3 0.0 8 591-598 118-125 (229)
83 74 6EJ2_A Beta-secretase 1 (E.C.3 38.0 28 0.00034 35.2 0.0 15 736-750 452-466 (501)
84 75 6ENY_F Beta-2-microglobulin, T 37.9 28 0.00034 33.9 0.0 6 592-597 215-220 (341)
85 76 5XTH_0 NADH dehydrogenase [ubi 37.1 29 0.00035 33.4 0.0 32 732-763 65-96 (144)
86 77 5B1A_D Cytochrome c oxidase su 33.8 36 0.00044 33.1 0.0 32 732-763 68-99 (147)
87 78 6PY2_A HLA class II histocompa 33.3 37 0.00045 31.4 0.0 9 591-599 143-151 (254)
88 79 6GJE_A Protein amnionless, Cub 33.2 37 0.00045 37.8 0.0 18 783-800 399-416 (453)
89 80 6C13_A Protocadherin-15; PCDH1 32.9 38 0.00046 35.0 0.0 13 693-705 508-520 (660)
90 81 5DJQ_P Cbb3-type cytochrome c 32.8 38 0.00046 27.7 0.0 24 748-771 7-35 (36)
91 82 1CD1_A CD1; CD1, IMMUNOLOGY, M 32.5 39 0.00047 31.8 0.0 7 592-598 217-223 (315)
92 83 6AT5_A HLA class I histocompat 29.9 46 0.00056 33.0 0.0 8 591-598 238-245 (362)
93 84 4JIX_A Uncharacterized protein 28.2 51 0.00062 27.7 0.0 41 371-421 68-108 (112)
94 85 4JIX_B Projannalysin; Hydrolas 28.2 51 0.00062 27.7 0.0 41 371-421 68-108 (112)
95 86 6IDF_E Nicastrin, Presenilin-1 27.6 53 0.00065 31.8 0.0 16 733-748 9-24 (129)
96 87 6IVA_D Oxaloacetate decarboxyl 26.5 58 0.0007 29.7 0.0 27 738-764 31-57 (104)
97 88 6IWW_B Oxaloacetate decarboxyl 26.5 58 0.0007 29.7 0.0 27 738-764 31-57 (104)
98 89 6BRJ_A Epithelial discoidin do 25.3 63 0.00076 37.1 0.0 7 602-608 254-260 (876)
99 90 3EHB_B Cytochrome c oxidase su 25.2 63 0.00076 33.8 0.0 47 725-771 47-93 (298)
100 91 6PY2_B HLA class II histocompa 24.3 67 0.00082 30.1 0.0 11 745-755 235-245 (261)
101 92 1Q5B_C EP-cadherin, ectodomain 24.1 68 0.00082 35.0 0.0 12 155-166 149-160 (880)
102 93 2JO1_A Phospholemman; FXYD1, N 23.9 69 0.00084 29.3 0.0 30 747-776 20-49 (72)
103 94 2KV5_A Putative uncharacterize 23.5 71 0.00086 25.4 0.0 27 745-771 4-31 (33)
104 95 6BSD_A Epithelial discoidin do 23.3 72 0.00088 36.6 0.0 7 602-608 254-260 (876)
105 96 6KOE_F AA3-600 quinol oxidase 22.6 76 0.00092 33.7 0.0 40 732-771 11-50 (296)
106 97 6KOB_B AA3-600 quinol oxidase 22.6 76 0.00092 33.7 0.0 40 732-771 11-50 (296)
107 98 1Q90_G Apocytochrome f, Cytoch 22.4 78 0.00094 26.3 0.0 29 744-772 5-33 (37)
108 99 2GSM_B Cytochrome c oxidase su 21.9 80 0.00097 31.8 0.0 6 721-726 4-9 (262)
109 100 3HB3_B Cytochrome c oxidase su 21.5 83 0.001 32.9 0.0 47 725-772 47-94 (298)
110 101 5X5V_A GD; herpes simplex viru 20.1 93 0.0011 35.6 0.0 28 742-769 355-382 (402)
111
112 No 1
113 >6M18_B Sodium-dependent neutral amino acid transporter; ACE2-B0AT1 complex, MEMBRANE PROTEIN; HET: 3PH, NAG; 2.9A {Homo sapiens}
114 Probab=100.00 E-value=3.9e-194 Score=1504.77 Aligned_cols=804 Identities=100% Similarity=1.532 Sum_probs=737.6 Template_Neff=7.700
115
116 Q sp|Q9BYF1|ACE2 2 SSSSWLLLSLVAVTAA--------QSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFL 73 (805)
117 Q Consensus 2 sssswlllslvavtaa--------qstieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsafl 73 (805)
118 +.+.|++++||+++++ +++.|++|++||++++.+++++.+++++|+|+|+||+|+++.+.++.+..+|++|+
119 T Consensus 3 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~e~~a~~~L~~~d~~~~~l~~~~~~A~w~y~tn~t~e~~~~~~ea~~~ls~f~ 82 (814)
120 T 6M18_B 3 SSSSWLLLSLVAVTAAWSHPQFEKQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFL 82 (814)
121 T ss_dssp ---------------------------CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCSTTHHHHHHHHHHHHHHH
122 T ss_pred hHHHHHHHHHHHHHHhcCCcccCCCCCcHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHH
123 Confidence 4678999999999999 99999999999999999999999999999999999999999999999999999999
124
125
126 Q sp|Q9BYF1|ACE2 74 KEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMA 153 (805)
127 Q Consensus 74 keqstlaqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneima 153 (805)
128 ++.++.++.|+++.+++-..|.||+.+++.|...|++++.++++.+++.|+++|+++.+|.+++|.+|+.++|++..+|+
129 T Consensus 83 ~~~~~~~~~~~~~~~~d~~~kr~L~~l~~~~~~~Ls~~~~~~l~~~~~~m~~~ys~~~v~~~~~p~~~~~L~~~l~~il~ 162 (814)
130 T 6M18_B 83 KEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMA 162 (814)
131 T ss_dssp HHHHHHGGGSCTTSCCCHHHHHHHHHHHCCGGGGSCTTHHHHHHHHHHHHHHHHHHCEEECSSCTTCEEECCCCCHHHHH
132 T ss_pred HHHHHHHhhcChhhcCCHHHHHHHHHHHHcCccCCCHHHHHHHHHHHHHHHHHHHcCCcCCCCCCCcccccCHHHHHHHh
133 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
134
135
136 Q sp|Q9BYF1|ACE2 154 NSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEI 233 (805)
137 Q Consensus 154 nsldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeei 233 (805)
138 ++-|+.+|.++|+.|++.+++.++|+|+++|-++|++|+.+.|+||+|||+.+|+.++.++|||++.++.+.++..+++|
139 T Consensus 163 ~s~D~~~R~~aw~a~~~~~~~~~~~~l~~lv~lrne~Akl~Gy~sy~d~~l~~~e~~~~~~~~ys~~~~~~~Le~L~~~i 242 (814)
140 T 6M18_B 163 NSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEI 242 (814)
141 T ss_dssp HCCCHHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHTTTCSSHHHHHGGGGCBCSSSSCCBCSSHHHHHHHHHHHHH
142 T ss_pred cCCCHHHHHHHHHHHHhHhcHHhHHHHHHHHHHHHHHHHhCCCCCHHHHHHhhhccCCCCCCCCCHHHHHHHHHHHHHHH
143 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
144
145
146 Q sp|Q9BYF1|ACE2 234 KPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEK 313 (805)
147 Q Consensus 234 kplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaek 313 (805)
148 +|+|+.||+|+|.++...|++.|++-+++|+|+||+|||++|+++|.+++||.+++++|+|++|+.+.|...++|+.+++
149 T Consensus 243 ~ply~~l~ayvr~kl~~~yg~~i~~~~~iPahllg~~~~~~w~~~y~~~~p~~~~~~~dv~~~~~~~~~t~~~~~~~a~~ 322 (814)
150 T 6M18_B 243 KPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEK 322 (814)
151 T ss_dssp HHHHHHHHHHHHHHHTTTSTTSSCTTBCEEGGGSSSSSSSCCGGGHHHHCSSTTSCCCCCTTHHHHTTCCTTHHHHHHHH
152 T ss_pred HHHHHHHHHHHHHHHHHHCcccCCCCCCCcHHHhHhhhHHHHHHhhcccCCCCCCCCCCCcHHHHhcCCCHHHHHHHHHH
153 Confidence 99999999999999999888777888999999999999999999999999999999999999999999999999999999
154
155
156 Q sp|Q9BYF1|ACE2 314 FFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLR 393 (805)
157 Q Consensus 314 ffvsvglpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllr 393 (805)
158 ||.++|++.|+++||++++++.|+.-..++|||++||.+.+|+||+||++++|+||+|.||||||++|.|.|..||++.|
159 T Consensus 323 ~f~~lgl~~~~~~fw~~s~~~r~~K~~~~~C~~~a~d~~~~d~rI~~~~~~~~~d~~tl~HE~GHa~h~~~~~~qp~~~~ 402 (814)
160 T 6M18_B 323 FFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLR 402 (814)
161 T ss_dssp HHHHTTCCCCCSSTTTSCBCSCCCSSCCCCCSCEEEECSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHTTSTTSCGGGC
162 T ss_pred HHHhcCCCCCCCCcccHHhccCCCCCCCCCcCchHhcCCCCCeEEEeecCCCHHHHHHHHHHHHHHHHHHHhccCCchhc
163 Confidence 99999999999999999999999988899999999999889999999999999999999999999999999999999999
164
165
166 Q sp|Q9BYF1|ACE2 394 NGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQW 473 (805)
167 Q Consensus 394 nganegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqw 473 (805)
168 .|++.+||||++++|++++.+|+||+++|++.++++++.+.+||+|++++|++++++||.+++++|||.+|.|++++++|
169 T Consensus 403 ~~a~~~f~Eavsel~el~~~~p~~L~~~~ll~~~~~~~~~~~in~ll~~aL~~l~~lp~~~~~d~~r~~~f~g~i~~~~l 482 (814)
170 T 6M18_B 403 NGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQW 482 (814)
171 T ss_dssp SCSSTTSHHHHHHHHHHHSSSHHHHHHHTCSCSSCCCCTTHHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHTSSCGGGH
172 T ss_pred cCCChHHHHHHHHHHHHHhhCHHHHHHccCcCCCCCCCcHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHhcCCCCHHHH
173 Confidence 99999999999999999999999999999999988888899999999999999999999999999999999999999999
174
175
176 Q sp|Q9BYF1|ACE2 474 MKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQK 553 (805)
177 Q Consensus 474 mkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqk 553 (805)
178 ++.||++.++..|++.|+++++++|||++.+|+.+++.+++|++.++++||+.+++|+.+.|+||||+||+++++++|++
179 T Consensus 483 n~~w~el~~~y~Gv~~p~~~~~~~~d~~~~~Hi~~~~~Yy~Y~~s~i~a~qi~~~l~~~~~~~~pl~~c~~~~s~~ag~~ 562 (814)
180 T 6M18_B 483 MKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQK 562 (814)
181 T ss_dssp HHHHHHHCCCCCCEECSSCCCTTCCGGGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCTTHHHH
182 T ss_pred HHHHHHHHHHHcCCCCCCCCCccCCCHHHHhhhhcCcchHHHHHHHHHHHHHHHHHHHHcccCCCchhCCCCCCHHHHHH
183 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
184
185
186 Q sp|Q9BYF1|ACE2 554 LFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAY 633 (805)
187 Q Consensus 554 lfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyadqsikvrislksalgdkay 633 (805)
188 |.+||+.|.|.||+-+++.+.|...+++.|+++||+||.+||+.+|++..+||.++|+||.+++||||||||+||||+||
189 T Consensus 563 l~~lL~~G~S~~~~ell~~~~G~~~~s~~~ll~yf~pL~~wL~~~n~~~~~gw~~~~~~~~~~~~~~~~~~~~~~~~~~~ 642 (814)
190 T 6M18_B 563 LFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYADQSIKVRISLKSALGDKAY 642 (814)
191 T ss_dssp HHHHHTTTTSSCHHHHHHTTTSCSSCCSHHHHHHTHHHHHHHHHHTSSSCCSCBTTCCTTSSSCEEEEECHHHHTSSSCC
192 T ss_pred HHHHHhcCCCCCHHHHHHHHHCCCCCCcHHHHHhHHHHHHHHHHhccCCCCCCCCCCCCCCCCcceeEEEcchhcCcccc
193 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
194
195
196 Q sp|Q9BYF1|ACE2 634 EWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRIND 713 (805)
197 Q Consensus 634 ewndnemylfrssvayamrqyflkvknqmilfgeedvrvanlkprisfnffvtapknvsdiiprtevekairmsrsrind 713 (805)
198 +||+||||||||++|||||+||.++|+|.+.|..+||.|.|.+|||||.|+||.|.|+|++||+.|||+||||||.|||+
199 T Consensus 643 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 722 (814)
200 T 6M18_B 643 EWNDNEMYLFRSSVAYAMRQYFLKVKNQMILFGEEDVRVANLKPRISFNFFVTAPKNVSDIIPRTEVEKAIRMSRSRIND 722 (814)
201 T ss_dssp CCCHHHHHHHHHHHHHHHHHHHHHTSCCCCCCCGGGEEEECCCTTSEEEEEEEETTEEEEECCHHHHHHHHHHTHHHHHH
202 T ss_pred cCChhhHHHHHHHHHHHHHHHHHHHccceeecccccEEEecCCCcEEEEEEEecCCCccccCCHHHHHHHHHhchhhhhh
203 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
204
205
206 Q sp|Q9BYF1|ACE2 714 AFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNP 793 (805)
207 Q Consensus 714 afrlndnsleflgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkknkarsgenpyasidiskgennp 793 (805)
208 ||+|+|++|||+||+|||+||.+|||.|||||||||||++||||++||++|||+||||+|+++++|||+++|+++|++||
209 T Consensus 723 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 802 (814)
210 T 6M18_B 723 AFRLNDNSLEFLGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGENPYASIDISKGENNP 802 (814)
211 T ss_dssp HHTCCSSSEECSSCCCCCCCCCCCSSCTHHHHHHHHHHHHHHHHHHHHTTTTTTC-------------------------
212 T ss_pred hhhcCCCceeecccCCCCCCCCCCCcchHHHHHHHHHHHHHHHHHHHHHhChhhHHHHccccCCCCCCccccccCCccCc
213 Confidence 99999999999999999999999999999999999999999999999999999999999999899999999999999999
214
215
216 Q sp|Q9BYF1|ACE2 794 GFQNTDDVQTSF 805 (805)
217 Q Consensus 794 gfqntddvqtsf 805 (805)
218 |||++||+||||
219 T Consensus 803 ~~~~~~~~~~~~ 814 (814)
220 T 6M18_B 803 GFQNTDDVQTSF 814 (814)
221 T ss_dssp ------------
222 T ss_pred ccCCCcccccCC
223 Confidence 999999999998
224
225
226 No 2
227 >1R42_A angiotensin I converting enzyme 2; zinc metallopeptidase domain, collectrin homology; HET: NAG; 2.2A {Homo sapiens} SCOP: d.92.1.5
228 Probab=100.00 E-value=3.4e-78 Score=581.98 Aligned_cols=615 Identities=100% Similarity=1.557 Sum_probs=553.7 Template_Neff=10.000
229
230 Q sp|Q9BYF1|ACE2 1 MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLA 80 (805)
231 Q Consensus 1 msssswlllslvavtaaqstieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstla 80 (805)
232 |++++|+|++||+++++.+..++.+.+++++++.+...+....+++.|.+.++.+++..+....+..+.+.++.+..+..
233 T Consensus 1 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~ 80 (615)
234 T 1R42_A 1 MSSSSWLLLSLVAVTAAQSTIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLA 80 (615)
235 T ss_dssp ------------------CCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHTTT
236 T ss_pred ChhHHHHHHHHHHHHhcCCCcHHHHHHHHHHHHHHHHHHHhHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHH
237 Confidence 78999999999999999999999999999999999999999999999999999999999988889999999999999988
238
239
240 Q sp|Q9BYF1|ACE2 81 QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE 160 (805)
241 Q Consensus 81 qmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldyne 160 (805)
242 ..|.+..+.+-..+-+|+.+...+...|+++..++++..++.|...|++..+|.++.|.+|+.+.|.+..+|+++-|...
243 T Consensus 81 ~~~~~~~~~~~~~~~~l~~~~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~ 160 (615)
244 T 1R42_A 81 QMYPLQEIQNLTVKLQLQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNE 160 (615)
245 T ss_dssp TTSCSTTCCCHHHHHHHHHHTCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEEETTEEEEEEETTTBHHHHHHHCCCHHH
246 T ss_pred hhCChhhcCCHHHHHHHHHHHhcCccCCCHHHHHHHHHHHHHHHHHHhcCCccCCCCCCcccccChhHHHHHhcCCCHHH
247 Confidence 88887766666777788877777777888888888889999999999999999888888899888999999999999999
248
249
250 Q sp|Q9BYF1|ACE2 161 RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL 240 (805)
251 Q Consensus 161 rlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehl 240 (805)
252 |-.+|++|+...++.+.+++.+.+-+++++|+...|++|.|||..++++++++++||+..++.+.++..++.++|+|+.+
253 T Consensus 161 R~~~~~~~~~~~~~~~~~~l~~lv~lr~~~A~~~Gy~~~~~~~l~~~~~~~~~~~~y~~~~~~~~l~~l~~~v~p~~~~~ 240 (615)
254 T 1R42_A 161 RLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHL 240 (615)
255 T ss_dssp HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTTCBCSCTTTCBCSHHHHHHHHHHHHHHHHHHHHH
256 T ss_pred HHHHHHHHHHHhhHHhHHHHHHHHHHHHHHHHHCCCCCHHHHHHHhhccCCCCCCCCChhHHHHHHHHHHHHHHHHHHHH
257 Confidence 99999999998889999999999999999999999999999999999999999999999999999999999999999999
258
259
260 Q sp|Q9BYF1|ACE2 241 HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL 320 (805)
261 Q Consensus 241 hayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvgl 320 (805)
262 |+|+|.++...|+.-+++-+..|+|++|.||+..|+.+|....|+.+.+..+++..++.+.|..+++++.++++|-++|+
263 T Consensus 241 ~~~~~~~~~~~~~~~~~~~~l~p~d~~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~ 320 (615)
264 T 1R42_A 241 HAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGL 320 (615)
265 T ss_dssp HHHHHHHHHHHSTTTSCTTBCEEGGGSSSSSCSCCGGGHHHHCTTTTSCCCCCTTTTGGGTCCHHHHHHHHHHHHHTTTC
266 T ss_pred HHHHHHHHHHHCccCCCCCCCccHHHccccchhcchhhHhccCCCCCCCCCCCcHHHHHCCCCHHHHHHHHHHHHHHcCC
267 Confidence 99999987766664445567889999999999999999999999999988999999999999999999999999999999
268
269
270 Q sp|Q9BYF1|ACE2 321 PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF 400 (805)
271 Q Consensus 321 pnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegf 400 (805)
272 ..++..+|.++++..+|....+.|+|.+|+.+.++.||++|...+.+|+.|.+||+||..|.+.+..||++.+.+++.+|
273 T Consensus 321 ~~~~~~~w~~~~~~r~~K~~~~~c~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~ 400 (615)
274 T 1R42_A 321 PNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF 400 (615)
275 T ss_dssp CCCCTTHHHHCBCSCCCTTCCCCCSCEEEEEETTEEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSTTH
276 T ss_pred ccCCcchhhhhccCCCCCCCCCccccchhcCCCCceEEEecCCCCHHHHHHHHHHHHHHHHHHHhccCCchHcCCCChHH
277 Confidence 99999999999998888877899999999887789999999999999999999999999999999899999998899999
278
279
280 Q sp|Q9BYF1|ACE2 401 HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM 480 (805)
281 Q Consensus 401 heavgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwem 480 (805)
282 +|+++++|+..+.+|.+|+.++++....+...+.+++.++++++..+..+|+.++++.|+|.+|.|+++.+++-+.||+.
283 T Consensus 401 ~E~~s~~~e~~~~~~~~l~~~~~~~~~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~~~~~~~~l 480 (615)
284 T 1R42_A 401 HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM 480 (615)
285 T ss_dssp HHHHHHHHHHHHHSHHHHHHTTSSCTTSCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTCSCGGGHHHHHHHH
286 T ss_pred HHHHHHHHHHHhcCHHHHHHcCCCCcccCCCcHHHHHHHHHHHHHHHhhccHHHHHHHHHHHHHcCCCCHHHHHHHHHHH
287 Confidence 99999999999999999999999876655555668889999999999999999999999999999999889999999999
288
289
290 Q sp|Q9BYF1|ACE2 481 KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL 560 (805)
291 Q Consensus 481 kreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrl 560 (805)
292 .++..|+..|++.++...++++..|...+..++.|....+..+|+-+++|+...++||||.|++.++.++|+++.++|+.
293 T Consensus 481 ~~~y~g~~~~~~~~~~~~~~~~~~H~~~~~~Yy~Y~~s~~~a~ql~~~~~~~~~~~~~l~~~~~~~~~~~g~~~~~~l~~ 560 (615)
294 T 1R42_A 481 KREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRL 560 (615)
295 T ss_dssp CCCCCCEECSSCCCTTCCGGGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHTTTCCSCGGGCCCTTCHHHHHHHHHHHTT
296 T ss_pred HHHHcCCCCCCCCCcccCChhHcccccCChhHHHHHHHHHHHHHHHHHHHHHhccCCChhhcCcCCChHHHHHHHHHHhc
297 Confidence 99999988777777788899988898766666888899999999999999988889999999999999999999999999
298
299
300 Q sp|Q9BYF1|ACE2 561 GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (805)
301 Q Consensus 561 gksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyad 615 (805)
302 |.+.||.-.++.+.|....+..+++.+|+||.+||+.+|++..+||.++|+|++|
303 T Consensus 561 G~s~~~~ell~~~~g~d~~s~~~~~~~~~~l~~~l~~~~~~~~~gw~~~~~~~~~ 615 (615)
304 T 1R42_A 561 GKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (615)
305 T ss_dssp TTSSCHHHHHHHHHSSSSCCSHHHHHHHHHHHHHHHHHTSSSCCSCBSSCCTTCC
306 T ss_pred CCCCCHHHHHHHHHCCCCCChHHHHHhHHHHHHHHHHHhcCCCCCCCCCCCCcCC
307 Confidence 9999999999999999889999999999999999999999999999999999985
308
309
310 No 3
311 >6LZG_A Angiotensin-converting enzyme 2 (E.C.3.4.17.23), Spike; Novel Coronavirus, Spike protein, receptor; HET: NAG; 2.5A {Homo sapiens}
312 Probab=100.00 E-value=5.4e-74 Score=545.88 Aligned_cols=597 Identities=100% Similarity=1.567 Sum_probs=545.8 Template_Neff=10.300
313
314 Q sp|Q9BYF1|ACE2 19 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 98 (805)
315 Q Consensus 19 stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlq 98 (805)
316 ||.++.+..+++.++.....+-...+++.|.++++.+++..+..+.+..+.+.+..+.+.....+.+..+.+-..+-+|+
317 T Consensus 1 ~~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~ 80 (597)
318 T 6LZG_A 1 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 80 (597)
319 T ss_dssp CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCGGGCCCHHHHHHHH
320 T ss_pred CChHHHHHHHHHHHHHHHHHHHhHHHhHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHhcCChhhcCCHHHHHHHH
321 Confidence 35567788999999999999999999999999999999988888888899999998888877777766666666777788
322
323
324 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRP 178 (805)
325 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrp 178 (805)
326 .+...+...|+++..++++.+++.+..+|++...|.+++|.+|+.+.+.+..+|+++-|...|.-+|++|++..++.+.+
327 T Consensus 81 ~~~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~ 160 (597)
328 T 6LZG_A 81 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRP 160 (597)
329 T ss_dssp HHHCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEECTTCTTCEEECCCCCHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
330 T ss_pred HHHhcCccCCCHHHHHHHHHHHHHHHHHHhcCCccCCCCCCceeccCccHHHHHhcCCCHHHHHHHHHHHHHHhcHHhHH
331 Confidence 77777778889988888889999999999999999998889999999999999999999999999999999988889999
332
333
334 Q sp|Q9BYF1|ACE2 179 LYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISP 258 (805)
335 Q Consensus 179 lyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp 258 (805)
336 ++.+.|.+++++|+.+.|++|.|||...+++++++++||+..++.+-++..++.|+|+|+.+|+|+|.++...|..-+++
337 T Consensus 161 ~l~~lv~~r~~~A~~~Gy~~~~~~~l~~~~~~~~~~~~~~~~~~~~~l~~l~~~v~p~~~~~~~~~~~~~~~~~~~~~~~ 240 (597)
338 T 6LZG_A 161 LYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISP 240 (597)
339 T ss_dssp HHHHHHHHHHHHHHHTTCSSHHHHHHGGGCBCSCTTTCBCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTTCCS
340 T ss_pred HHHHHHHHHHHHHHHCCCCCHHHHHHHhhccCCCCCCCCchhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCccCCC
341 Confidence 99999999999999999999999999999999999999999999999999999999999999999999877766543445
342
343
344 Q sp|Q9BYF1|ACE2 259 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 338 (805)
345 Q Consensus 259 igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgn 338 (805)
346 -+..|+|++|.+|+..|+++|....|+.+.+..++++.+..+.+..+++++.++++|-++|+..+...+|+++.+..++.
347 T Consensus 241 ~~~~p~d~~~~~~~~~~~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~~~~r~~k 320 (597)
348 T 6LZG_A 241 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 320 (597)
349 T ss_dssp SSCEETTSSSSSSCSCCGGGHHHHCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCCS
350 T ss_pred CCCCcHHHcccchhhhhhhhHhccCCCCCCCCCCCcHHHHHcCCCHHHHHHHHHHHHHHcCCccCCcchhhhhccCCCCC
351 Confidence 57899999999999999999999999999888889998888899999999999999999999999999999998888888
352
353
354 Q sp|Q9BYF1|ACE2 339 VQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHL 418 (805)
355 Q Consensus 339 vqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhl 418 (805)
356 ...+.|+|.+|+...++.||++|...+.+|+.+.+||+||..|.+.+..||++++.+++.+|+|+++++|+..+.+|.+|
357 T Consensus 321 ~~~~~c~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HElGHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~L 400 (597)
358 T 6LZG_A 321 VQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHL 400 (597)
359 T ss_dssp SSCCCCSCEEEEEETTEEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSTTHHHHHHHHHHHHHHSHHHH
360 T ss_pred CCCCccCccHhcCCCCcEEEEecCCCCHHHHHHHHHHHHHHHHHHHhccCCchhcCCCChHHHHHHHHHHHHHhcCHHHH
361 Confidence 78899999999876689999999999999999999999999999999999999988889999999999999999999999
362
363
364 Q sp|Q9BYF1|ACE2 419 KSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYC 498 (805)
365 Q Consensus 419 ksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc 498 (805)
366 +.++++....+.+.+..++.++.+++..+..+|+..+++.|+|-+|.|+++.+.+.+.||+...+..|++.|++.++...
367 T Consensus 401 ~~~~l~~~~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~~~~~ 480 (597)
368 T 6LZG_A 401 KSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYC 480 (597)
369 T ss_dssp HHTTSSCTTCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTCSCGGGHHHHHHHHCCCCCCEECSSCCCTTCC
370 T ss_pred HHcCCCCcccCCChHHHHHHHHHHHHHHHhhchhHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCCcccC
371 Confidence 99998876554455667888999999999999999999999999999999999999999999999999988776667778
372
373
374 Q sp|Q9BYF1|ACE2 499 DPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKN 578 (805)
375 Q Consensus 499 dpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgakn 578 (805)
376 ++++..|+..+..+..|....+..+|+.+.+|+...++||+|.|++.++.++|+++.++|+.|.+.+|.-.++.+.|...
377 T Consensus 481 ~~~~~~H~~~~~~Yy~Y~~~~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~G~s~~~~ell~~~~g~~~ 560 (597)
378 T 6LZG_A 481 DPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKN 560 (597)
379 T ss_dssp GGGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSCSS
380 T ss_pred ChhHccccccChhHHHHHHHHHHHHHHHHHHHHHhccCCChhhCCcCCCHHHHHHHHHHHhcCCCCCHHHHHHHHHCCCC
381 Confidence 88888887655555888899999999999999988889999999999999999999999999999999999999999988
382
383
384 Q sp|Q9BYF1|ACE2 579 MNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (805)
385 Q Consensus 579 mnvrpllnyfeplftwlkdqnknsfvgwstdwspyad 615 (805)
386 .+..++++||+||..||+.+|++..+||.++|.|++|
387 T Consensus 561 ~~~~~l~~~~~~l~~~l~~~~~~~~~gw~~~~~~~~~ 597 (597)
388 T 6LZG_A 561 MNVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 597 (597)
389 T ss_dssp CCSHHHHHHHHHHHHHHHHHGGGSCCSCCSSCCTTC-
390 T ss_pred CCcHHHHHhHHHHHHHHHHhhcCCCCCCCCCCCCCCC
391 Confidence 8899999999999999999999999999999999985
392
393
394 No 4
395 >3D0I_B Crystal structure of spike protein; SARS coronavirus, spike protein, receptor-binding; HET: NAG, NDG; 2.9A {Paguma larvata}
396 Probab=100.00 E-value=1.2e-73 Score=545.19 Aligned_cols=596 Identities=98% Similarity=1.548 Sum_probs=544.0 Template_Neff=10.200
397
398 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 99 (805)
399 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqa 99 (805)
400 |-++.++.|+++++.....+-...+.+.|.++++.+++..+....+-.+.+.+.++.......|.+..+.+-..+-+|+.
401 T Consensus 2 ~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~ 81 (597)
402 T 3D0I_B 2 TTEELAKTFLETFNYEAQELSYQSSVASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 81 (597)
403 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCCHHHHHHHHHHHHHHHHHHHHHHHHHHTSCGGGCCCHHHHHHHHH
404 T ss_pred ccHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHhhCChhhcCCHHHHHHHHH
405 Confidence 33567788999999999999999999999999999999888888888899999888887777777666666667778888
406
407
408 Q sp|Q9BYF1|ACE2 100 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPL 179 (805)
409 Q Consensus 100 lqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrpl 179 (805)
410 +...+...|+++...+++.+.+.+..+|++..+|.+++|.+|+.+.+.+..+|.++-|...|..+|++|+...+..+.+.
411 T Consensus 82 l~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~ 161 (597)
412 T 3D0I_B 82 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPL 161 (597)
413 T ss_dssp HSCCTGGGSCHHHHHHHHHHHHHHHHHHHHCEEEETTEEEEEEECCCCCHHHHHHCCCHHHHHHHHHHHHHTHHHHHHHH
414 T ss_pred HHhcCccCCCHHHHHHHHHHHHHHHHHHhcCCccCCCCCCcccccCccHHHHHhcCCCHHHHHHHHHHHHHHhcHHhHHH
415 Confidence 88888888999888888899999999999999998888888998888999999999999999999999998888899999
416
417
418 Q sp|Q9BYF1|ACE2 180 YEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI 259 (805)
419 Q Consensus 180 yeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispi 259 (805)
420 +.+.+.+++++|+.+.|++|.+||-.++++++.+++||+..++.+-++..++.|+|+|+.+|+|+|.++...|..-+++-
421 T Consensus 162 l~~lv~lr~~~A~~~Gy~~~~~~~l~~~~~~~~~~~~~~~~~~~~~l~~l~~~i~p~~~~~~~~~~~~~~~~~~~~~~~~ 241 (597)
422 T 3D0I_B 162 YEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPI 241 (597)
423 T ss_dssp HHHHHHHHHHHHHHTTCSSHHHHHHGGGCBCSSSSSCBCHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHSTTSCCTT
424 T ss_pred HHHHHHHHHHHHHHCCCCCHHHHHHHhcccCCCCCCCCChhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCcccCCCC
425 Confidence 99999999999999999999999999999999999999999999999999999999999999999998776664334455
426
427
428 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
429 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
430 ...|+|++|+||+.-|+.+|....|+.+.+..+++..++.+.+...++++.++++|-++|+..+...||+++....++..
431 T Consensus 242 ~~~p~~~~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~~~~r~~K~ 321 (597)
432 T 3D0I_B 242 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 321 (597)
433 T ss_dssp BCEEGGGSSSSSCSCCGGGGGGTCSCTTSCCSCTHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCCSS
434 T ss_pred CCccHHHccccchhhchhhHhhcCCCCCCCCCCCcHHHHHcCCCHHHHHHHHHHHHHHcCCccCCcchHhhhccCCCCCC
435 Confidence 78999999999999999999999999998888999999888899999999999999999999999899999998888888
436
437
438 Q sp|Q9BYF1|ACE2 340 QKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 419 (805)
439 Q Consensus 340 qkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlk 419 (805)
440 ..+.|+|.+|++..++.||++|...+++|+.|.+||+||+.+.+.+..||++.+..++.+|.|+++++|+..+.+|.+|+
441 T Consensus 322 ~g~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~l~e~~~~~~~~L~ 401 (597)
442 T 3D0I_B 322 QKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 401 (597)
443 T ss_dssp SCCCCSCEEEEEETTEEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSTTHHHHHHHHHHHHHHSHHHHH
444 T ss_pred CCCccCccHhhcCCCcEEEEecCCCCHHHHHHHHHHHHHHHHHHHhccCChhHcCCCChHHHHHHHHHHHHHhcCHHHHH
445 Confidence 88999999999877899999999999999999999999999999998999999888899999999999999999999999
446
447
448 Q sp|Q9BYF1|ACE2 420 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
449 Q Consensus 420 sigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
450 .++++........+..++.++.+++..+..+|+.++++.|+|.+|.|+++.+.+.+.||+..++..|+..|++.++...+
451 T Consensus 402 ~~~~~~~~~~~~~~~~~~~l~~~~l~~l~~l~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~y~g~~~~~~~~~~~~~ 481 (597)
452 T 3D0I_B 402 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 481 (597)
453 T ss_dssp HHTSSCSSCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCSCTTTTTHHHHHHHHHTSCEECSSCCCTTCCC
454 T ss_pred HcCCCCcccCCChHHHHHHHHHHHHHHHhcchHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCCcccCC
455 Confidence 99988765444455677889999999999999999999999999999998899999999999999998887776667778
456
457
458 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 579 (805)
459 Q Consensus 500 paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknm 579 (805)
460 +++..|+..+..++.|....+..+|+.+.+|+...+.||+|.||+..+.++|+++.++|+.|.+.+|.-.++...|....
461 T Consensus 482 ~~~~~H~~~~~~Yy~Y~~s~~~a~~i~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~~G~s~~~~ell~~~~g~d~~ 561 (597)
462 T 3D0I_B 482 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 561 (597)
463 T ss_dssp GGGSHHHHTTCCCTHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSCSSC
464 T ss_pred hhHccccccChhHHHHHHHHHHHHHHHHHHHHHhcccCChhhcCcCCCHHHHHHHHHHHhcCCCCCHHHHHHHHHCCCCC
465 Confidence 88888887655558888899999999999999888899999999999999999999999999999999999999999888
466
467
468 Q sp|Q9BYF1|ACE2 580 NVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 615 (805)
469 Q Consensus 580 nvrpllnyfeplftwlkdqnknsfvgwstdwspyad 615 (805)
470 ++.+++.+|+||..||+.+|++..+||.++|.|++|
471 T Consensus 562 ~~~~~~~~~~~l~~~l~~~~~~~~~gw~~~~~~~~~ 597 (597)
472 T 3D0I_B 562 NVRPLLNYFEPLFTWLKDQNKNSFVGWSTDWSPYAD 597 (597)
473 T ss_dssp CSHHHHHHHHHHHHHHHHHGGGSCCSCBTTCCSSCC
474 T ss_pred CcHHHHHhHHHHHHHHHHhhcCCCCCCCCCCCCCCC
475 Confidence 899999999999999999999999999999999985
476
477
478 No 5
479 >5AMB_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1), AMYLOID BETA; HYDROLASE, ANGIOTENSIN-CONVERTING ENZYME, METALLOPROTEASE, AMYLOID-BETA; HET: P6G, PG4, FUC, NAG, PEG, BMA; 1.55A {HOMO SAPIENS}
480 Probab=100.00 E-value=1.2e-69 Score=524.17 Aligned_cols=595 Identities=42% Similarity=0.814 Sum_probs=518.7 Template_Neff=10.000
481
482 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP---LQEIQNLTVKLQ 96 (805)
483 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp---lqeiqnltvklq 96 (805)
484 .-++.+.+||+.++.+...+-...+++.|.++++.+.+..+....+..+.+.+..+.++.+.... ++.+..-..+-+
485 T Consensus 12 ~~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~ 91 (629)
486 T 5AMB_A 12 ADEAGAQLFAQSYQSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQQFTDPQLRRI 91 (629)
487 T ss_dssp SSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTGGGCSCHHHHHH
488 T ss_pred CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhhccHHHhcCCHHHHHH
489 Confidence 34577889999999999999999999999999999999888888888888888887766433211 122233345556
490
491
492 Q sp|Q9BYF1|ACE2 97 LQALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQL 176 (805)
493 Q Consensus 97 lqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkql 176 (805)
494 |+.+...+...|+++..+++..+.+.|+.+|++...|.++.+..|+.+.+.+..+|+++-|...|.-+|+.|+...+..+
495 T Consensus 92 l~~l~~~~~~~L~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~ 171 (629)
496 T 5AMB_A 92 IGAVRTLGSANLPLAKRQQYNALLSQMSRIYSTAKVCLPQKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPL 171 (629)
497 T ss_dssp HHHHTCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEEC---CCCEEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHH
498 T ss_pred HHHHHHhcccCCCHHHHHHHHHHHHHHHHHHhhccccCCCCCCceeecChhHHHHHHhCCCHHHHHHHHHHHHHHhCccc
499 Confidence 66666666677888887888889999999999999998777778888888999999999999999999999999888999
500
501
502 Q sp|Q9BYF1|ACE2 177 RPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-Y 255 (805)
503 Q Consensus 177 rplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-y 255 (805)
504 ++++.+.|-+++++|+...|++|.+||..+|+. +...+.++..++.|+|+|+.+|+|+|.++...|.. .
505 T Consensus 172 ~~~l~~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~~~~~l~~l~~~i~~~~~~~~~~~~~~~~~~~g~~~ 241 (629)
506 T 5AMB_A 172 KPLYEDFTALSNEAYKQDGFTDTGAYWRSWYNS----------PTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRY 241 (629)
507 T ss_dssp HHHHHHHHHHHHHHHHTTTCSSHHHHHHHTTCC----------TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTT
508 T ss_pred HHHHHHHHHHHHHHHHHcCCCCHHHHHHHhhCC----------ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccc
509 Confidence 999999999999999999999999999887642 34556677888999999999999999987665542 2
510
511
512 Q sp|Q9BYF1|ACE2 256 ISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTD 335 (805)
513 Q Consensus 256 ispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltd 335 (805)
514 +++-+.+|+|++|++|+..|+++|.+++|+.+....+|++.++.+.+....+++.++++|.++|++.++..||++++...
515 T Consensus 242 ~~~~~~ip~dll~~~~~~~~~~~~~~~~p~~~~~~~~v~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~~~~~~~~~ 321 (629)
516 T 5AMB_A 242 INLRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWQATHMFRVAEEFFTSLELSPMPPEFWEGSMLEK 321 (629)
517 T ss_dssp CCTTSCEETTSSSSTTSCCCGGGHHHHCSCTTSCCCCTHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSC
518 T ss_pred cCCCCCCCHHHccChhhhhhhhhhcccccCCCCCCCCCcHHHHhcCCCHHHHHHHHHHHHHhCCCCCCChhHhhcccccC
519 Confidence 33445679999999999999999999999988888889999999888899999999999999999999999999999888
520
521
522 Q sp|Q9BYF1|ACE2 336 PGNVQKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAAT 414 (805)
523 Q Consensus 336 pgnvqkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaat 414 (805)
524 |+.....+|||.+|++.. ++.||++|...+++|+.|.+|||||..|.+.+..||++.+.+++.+|||+++++|+..+.+
525 T Consensus 322 ~~k~~~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~ 401 (629)
526 T 5AMB_A 322 PADGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVST 401 (629)
527 T ss_dssp CTTCCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCSSHHHHHHHHHHHHHHHTS
528 T ss_pred CCCCCccccccchhhccCCCCeEEEecCCCCHHHHHHHHHHHHHHHHHHHcCCCCHHHcCCCCHHHHHHHHHHHHHHhcC
529 Confidence 887777899999999985 7899999999999999999999999999999999999999999999999999999999999
530
531
532 Q sp|Q9BYF1|ACE2 415 PKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHD 494 (805)
533 Q Consensus 415 pkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphd 494 (805)
534 |.+|+.++++... +...+..++.++++++..+..+|+.++++.|+|.+|.|+++.+++.+.||+..++..|+..|.+.+
535 T Consensus 402 ~~~L~~~~~~~~~-~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~ 480 (629)
536 T 5AMB_A 402 PEHLHKIGLLDRV-TNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRN 480 (629)
537 T ss_dssp HHHHHHTTSCCCC-CCSHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTSSCGGGHHHHHHHHCCCCCCEECSSCCC
538 T ss_pred HHHHHHcCCCCCC-CCCcHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHhhCCCCChhhHHHHHHHHHHHhCCCCCCCCCC
539 Confidence 9999999987543 223345678899999999999999999999999999999999999999999999999987766667
540
541
542 Q sp|Q9BYF1|ACE2 495 ETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVV 574 (805)
543 Q Consensus 495 etycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvv 574 (805)
544 +...||++..|+..+..++.|....+.++|+-+.+|+...++||||+||+..+.++|+++.++|+.|.+.+|.-.++.+.
545 T Consensus 481 ~~~~~~~~~~H~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~pl~~~~~~~~~~~g~~~~~~L~~G~s~~~~ell~~~~ 560 (629)
546 T 5AMB_A 481 ETHFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLRAGSSRPWQEVLKDMV 560 (629)
547 T ss_dssp TTCCGGGGSTTTTTTCCCHHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHHHTTSSCHHHHHHHHH
548 T ss_pred cccCCcCcccccCCChhHHHHHHHHHHHHHHHHHHHHHcCCCCCcccCCccCCHHHHHHHHHHHhcCCCCcHHHHHHHHh
549 Confidence 78889999999876556889999999999999999998889999999999999999999999999999999999999999
550
551
552 Q sp|Q9BYF1|ACE2 575 GAKNMNVRPLLNYFEPLFTWLKDQNK--NSFVGWST-DWSPYADQSIKVRISLK 625 (805)
553 Q Consensus 575 gaknmnvrpllnyfeplftwlkdqnk--nsfvgwst-dwspyadqsikvrislk 625 (805)
554 |....+..+++.+|+||..||+.+|+ +.-+||.. +|.|++..+++++|++-
555 T Consensus 561 G~d~~~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~~~~~~~~~~~~~~~~ 614 (629)
556 T 5AMB_A 561 GLDALDAQPLLKYFQLVTQWLQEQNQQNGEVLGWPEYQWHPPLPDNYPEGIDLV 614 (629)
557 T ss_dssp SCSSCCSHHHHHHHHHHHHHHHHHHHHHTCCSSCSCTTCCCCCCTTCSCC----
558 T ss_pred CCCCCChHHHHHHHHHHHHHHHHHHHhcCcccCCcccCCCCCCCCCCCCCCCCC
559 Confidence 99889999999999999999999999 56699996 99999999999999983
560
561
562 No 6
563 >6H5W_A Angiotensin-converting enzyme (E.C.3.2.1.-,3.4.15.1); Angiotensin-1 converting enzyme, ACE inhibitor; HET: BO3, CSO, FUC, FT8, P6G, EDO, BMA, IMD, NAG; 1.37A {Homo sapiens}
564 Probab=100.00 E-value=4.4e-61 Score=455.72 Aligned_cols=579 Identities=43% Similarity=0.858 Sum_probs=503.4 Template_Neff=10.400
565
566 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
567 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
568 +..+..||+.++.....+-...+++.|.++++++++.++....+-.+.+.+..+..+.+..|..+.+.+-.++-.++.+.
569 T Consensus 5 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 84 (591)
570 T 6H5W_A 5 EAEASKFVEEYDRTSQVVWNEYAGANWNYNTNITTETSKILLQKNMQIAQHTLKYGTQARKFDVNQLQNTTIKRIIKKVQ 84 (591)
571 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCGGGCCCHHHHHHHHHHT
572 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhhHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcCcccCCCHHHHHHHHHHH
573 Confidence 55678899999999999999999999999999999999999989999999999888877766645555555666666666
574
575
576 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYE 181 (805)
577 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrplye 181 (805)
578 ..+...|+++....+..+...+..+|++.++|.++ .+|+.+.+.+..+|+++-|...|.-+|+.|+...+..++|.+.
579 T Consensus 85 ~~~~~~L~~~~~~~~~~l~~~~~~~~~~~~~~~~~--g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l~ 162 (591)
580 T 6H5W_A 85 DLERAALPAQELEEYNKILLDMETTYSVATVCHPQ--GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYP 162 (591)
581 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCEEECTT--SCEEECCCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHHTTTHH
582 T ss_pred hhhhccCCHHHHHHHHHHHHHHHhhhccceecCCC--CceecCChhHHHHHhhCCCHHHHHHHHHHHHHHhhHHhHHHHH
583 Confidence 66666778876667777788888999999999874 4677788899999999999999999999999887889999999
584
585
586 Q sp|Q9BYF1|ACE2 182 EYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPIG 260 (805)
587 Q Consensus 182 eyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispig 260 (805)
588 +.+-+++++|+...|++|.+||..+|+. +.+.+.++..++.++|+|+.+|+|+|.|+...+.. -+++-+
589 T Consensus 163 ~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~v~~~l~~l~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~ 232 (591)
590 T 6H5W_A 163 KYVELINQAARLNGYVDAGDSWRSMYET----------PSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEG 232 (591)
591 T ss_dssp HHHHHHHHHHHHTTCSSHHHHHHHTTCC----------TTHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHCGGGCCTTS
592 T ss_pred HHHHHHHHHHHHCCCCCHHHHHHhccCC----------ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccCCCCC
593 Confidence 9999999999999999999999887732 34557788889999999999999999987544432 244557
594
595
596 Q sp|Q9BYF1|ACE2 261 CLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQ 340 (805)
597 Q Consensus 261 clpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvq 340 (805)
598 -+|+|++|.+|+.-|+++|.++.|+...+..++++++..+.+...++++.++++|.+.|+..|..+||+++....|+...
599 T Consensus 233 ~~p~~~~~~~~~~~~~~~~~~~~p~~~~~~~~v~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~~~~~~~~~~~k~~ 312 (591)
600 T 6H5W_A 233 PIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWQKSMLEKPTDGR 312 (591)
601 T ss_dssp CEETTSSSSTTSSCCGGGHHHHCSCTTSCCCCHHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSSSC
602 T ss_pred CCcHHHchhhhhHhhHhhhhccCCCCCCCCCCcHHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChHHHhhccccCCCCCC
603 Confidence 88999999999999999999999998888888888877777888999999999999999988889999998877777655
604
605
606 Q sp|Q9BYF1|ACE2 341 KAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 419 (805)
607 Q Consensus 341 kavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlk 419 (805)
608 ..+|||.++++.. ++.||++|...+.+++.|.+||+||..|.+.+..||++++.++.-+|+|+++++|+..+.+|.+|+
609 T Consensus 313 ~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~l~ 392 (591)
610 T 6H5W_A 313 EVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLH 392 (591)
611 T ss_dssp CCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHHHH
612 T ss_pred cceecceeeeCcCCCceEEEecCCCCHHHHHHHHHHHHHHHHHHHhcCCCHHHccCCChHHHHHHHHHHHHHhcCHHHHH
613 Confidence 6799999999875 689999999999999999999999999999999999999888999999999999999999999999
614
615
616 Q sp|Q9BYF1|ACE2 420 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
617 Q Consensus 420 sigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
618 .++++... ..+.+..++.++.+++..+..+|+.++++.|+|-++.|.++.+++-+.||+...+..|+..|.+......|
619 T Consensus 393 ~~~~~~~~-~~~~~~~~~~l~~~~~~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~~~~~~ 471 (591)
620 T 6H5W_A 393 SLNLLSSE-GGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFD 471 (591)
621 T ss_dssp HTTSSCCC-CSCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTSSCTTTHHHHHHHHCCCCCCEECSSCCCTTCCG
622 T ss_pred hcCCCCCC-CCChHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHhCCCCCHHhHHHHHHHHHHHHcCCCCCCCCCcccCC
623 Confidence 99987653 23334467788899999999999999999999999999888889999999999999898766555566778
624
625
626 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 579 (805)
627 Q Consensus 500 paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknm 579 (805)
628 |++..|......+..|....+..+|+.+.+|+...|+||+|.|++..+.++|+++-++|+.|.+.+|.-.++...|..-.
629 T Consensus 472 ~~~~~H~~~~~y~y~Y~~~~~~a~ql~~~~~~~~~~~~~l~~~~~~~~~~~g~~~~~~l~~G~s~~~~ell~~~~g~d~~ 551 (591)
630 T 6H5W_A 472 PGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPQM 551 (591)
631 T ss_dssp GGGSTTTTTTCCSHHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSSCSC
632 T ss_pred CcccccCCCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCcccCCccCCHHHHHHHHHHHHcCCCCCHHHHHHHHHCCCCC
633 Confidence 88888888666778888888999999999999888899999999998899999999999999999999999999998878
634
635
636 Q sp|Q9BYF1|ACE2 580 NVRPLLNYFEPLFTWLKDQNKN--SFVGWST-DWSPY 613 (805)
637 Q Consensus 580 nvrpllnyfeplftwlkdqnkn--sfvgwst-dwspy 613 (805)
638 +..+++.+|+|+..||+.+|+. --+||.. .|.|-
639 T Consensus 552 ~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~~~~ 588 (591)
640 T 6H5W_A 552 SASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPN 588 (591)
641 T ss_dssp CSHHHHHHHHHHHHHHHHHHHHHTCCCSCSSTTCCCC
642 T ss_pred ChHHHHHhHHHHHHHHHHHHHhhCCccCCCccCCCCC
643 Confidence 8999999999999999999875 4599987 67664
644
645
646 No 7
647 >6S1Y_A Angiotensin-converting enzyme (E.C.3.4.-.-); metalloprotease, mosquito control, insecticide design; HET: PEG, EDO, NAG, BMA, KSN; 2.2A {Anopheles gambiae}
648 Probab=100.00 E-value=4.6e-59 Score=450.26 Aligned_cols=579 Identities=37% Similarity=0.727 Sum_probs=484.7 Template_Neff=10.000
649
650 Q sp|Q9BYF1|ACE2 21 IEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQAL 100 (805)
651 Q Consensus 21 ieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqal 100 (805)
652 -++++.++++.++.....+-...+++.|.++++.+.+..+....+-.+.+.+..+..+...-+....+..-..+-+++.+
653 T Consensus 11 ~~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~l~~~ 90 (621)
654 T 6S1Y_A 11 SETEISQIVEWIEQRYQQTKAHQTLAAWEYGSNLTEFNLSKKTKAAADFAEVAKAVAEELQQFKTDQLTNATLKRRIKKL 90 (621)
655 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCSSSCCCHHHHHHHHHH
656 T ss_pred CHHHHHHHHHHHHHHHHHHHHhHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCHHHHHHHHHH
657 Confidence 34677889999999999999999999999999999988887666777777777654432111111122233455566666
658
659
660 Q sp|Q9BYF1|ACE2 101 QQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNP-QECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPL 179 (805)
661 Q Consensus 101 qqngssvlsedkskrlntilntmstiystgkvcnpdnp-qeclllepglneimansldynerlwaweswrsevgkqlrpl 179 (805)
662 ...+...|+++..+++..++..++.+|++..+|.++.+ .+++.+.+.+..+|+++-|...|--+|++|++..+..+.++
663 T Consensus 91 ~~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~ 170 (621)
664 T 6S1Y_A 91 AKLGYAALPADQFKELLGAIASMESNYAKAKFCAYGDATKCDLSLDPELTEIFANHREPEELKYYWVQWYNATGAPVRES 170 (621)
665 T ss_dssp TCCGGGGSCHHHHHHHHHHHHHHHHHHHHCCBCBTTBTTCCCBCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHH
666 T ss_pred HHhccccCCHHHHHHHHHHHHHHHHHHHhhccccCCCCCCCcccCChHHHHHHHhCCCHHHHHHHHHHHHHhcChhHHHH
667 Confidence 66666678888777788888899999999888765422 23455668899999999999999999999999888899999
668
669
670 Q sp|Q9BYF1|ACE2 180 YEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISP 258 (805)
671 Q Consensus 180 yeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yisp 258 (805)
672 +.+.|-+++++|+...|.+|.+|+..++++ +.+.+-++..++.++|+++.+++|++.++...|.. -+++
673 T Consensus 171 l~~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~v~~~l~~l~~~v~~~~~~~~~~~~~~~~~~~g~~~~~~ 240 (621)
674 T 6S1Y_A 171 FQKYVELNRQAALRNNFSSGAAVWLNEYDD----------STFEQQVDDVIEQIRPLYEQLHAYVRYKLRQKYGDKLVSP 240 (621)
675 T ss_dssp HHHHHHHHHHHHHHTTCSSHHHHHHHTTCC----------TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCS
676 T ss_pred HHHHHHHHHHHHHHCCCCCHHHHHHhcCCc----------hhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccCCCCC
677 Confidence 999999999999999999999999876642 34556677788899999999999999987554432 3456
678
679
680 Q sp|Q9BYF1|ACE2 259 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 338 (805)
681 Q Consensus 259 igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgn 338 (805)
682 -+-+|+|+||.+|+.-|..+|.+..|+.+....++++.++.+-+..+++++.++++|-++|+..++..||++++...|..
683 T Consensus 241 ~~~ip~~~l~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~v~~~~~~ 320 (621)
684 T 6S1Y_A 241 TGPIPMHLLGNLWAQTWDNIADFTTPFPEKKLLDVTDEMIRQGYTPIKMFQMGDDFFTSLNMTKLPQTFWDKSILEKPTD 320 (621)
685 T ss_dssp SSCEEGGGSSSTTCSCCGGGTTTTCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSS
686 T ss_pred CCCCcHHHhhcchhccchhhhhhcCCCCCcccCCCcHHHHHCCCCHHHHHHHHHHHHHHCCCCCCChhHhhhhhccCCCC
687 Confidence 78999999999999999999999999876666778888988888899999999999999999999999999999875432
688
689
690 Q sp|Q9BYF1|ACE2 339 VQKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKH 417 (805)
691 Q Consensus 339 vqkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkh 417 (805)
692 -....|||..+.+.. +|.||++|+..+.+|+.|.+||+||..|.+.+..||++.+.+++.+|+|+++++|+..+.+|.+
693 T Consensus 321 ~k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~~~~~~~~~p~~~~~~~~~~~~E~~s~~~e~~~~~~~~ 400 (621)
694 T 6S1Y_A 321 GRDLVCHASAWDFFAIDDVRIKQCTRVNMREFFVVHHELGHIQYYLQYQHQPVEFRGGANPGFHEAVGDVLSLSVSTPKH 400 (621)
695 T ss_dssp CCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHH
696 T ss_pred CCCCCCchhhhhccCCCCEEEEeCCCCCHHHHHHHHHHHHHHHHHHHhccCCchhcCCCChHHHHHHHHHHHHHhcCHHH
697 Confidence 222468888888875 6999999999999999999999999999999999999999999999999999999999999999
698
699
700 Q sp|Q9BYF1|ACE2 418 LKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
701 Q Consensus 418 lksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
702 |+.++++.. .....+..++.++++++..+..+|+..++.+|++.++.|.+..+.+-+.||+...+..|+..|.+.++..
703 T Consensus 401 L~~~~l~~~-~~~~~~~~~~~l~~~~l~~l~~~~~~~~~d~fe~~l~~~~~~~~~l~~~~~~l~~~y~g~~~~~~~~~~~ 479 (621)
704 T 6S1Y_A 401 LKKVGLLKD-YEEDEQVKINQFYRAGVTKLVFLPFAYTLDKYRWGVFRGDIKPREYNCKFWEMRSRYSGVEPPVVRTEQD 479 (621)
705 T ss_dssp HHHTTSSCC-CCCCHHHHHHHHHHHCCCCCTHHHHHHHHHHHHHHHHHTSSCGGGHHHHHHHHHHHHHCEECSSCEETTC
706 T ss_pred HHHcCCCCC-CCCCHHHHHHHHHHHHHHHhhhhHHHHHHHHHHHHHHcCCCChHHHHHHHHHHHHHHcCCCCCCCCChhh
707 Confidence 999998753 3333345667888899999999999889999999999998877888999999999999976665566677
708
709
710 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALE 571 (805)
711 Q Consensus 498 cdpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlale 571 (805)
712 .||+...|+.....++.|....+..+|+-+.+|+...+ ++|||.||+..+.++|.++.++|+.|.+.+|.-.++
713 T Consensus 480 ~~~~~~~H~~~~~~~~~Y~~~~~~a~qi~~~~~~~~~~~~~~~~~~~l~~c~~~~~~~~~~~~~~~l~~G~s~~~~ell~ 559 (621)
714 T 6S1Y_A 480 FDPPAKYHVSADVEYLRYFVSYVIQFQFHRAACALAGEYVKGDPEKTLNNCDIYQSTAAGNQLKEMLALGSSKPWPDAME 559 (621)
715 T ss_dssp CCGGGSHHHHTTCCSHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCTTSCCCTTCHHHHHHHHHHHHTTTSSCHHHHHH
716 T ss_pred CCcchheeecCCchHHHHHHHHHHHHHHHHHHHHHhCCccCCCCCCCcccCCccCCHHHHHHHHHHHhcCCCCCHHHHHH
717 Confidence 88888888875556888999999999999999987643 579999999999999999999999999999999999
718
719
720 Q sp|Q9BYF1|ACE2 572 NVVGAKNMNVRPLLNYFEPLFTWLKDQNKN--SFVGWSTDW 610 (805)
721 Q Consensus 572 nvvgaknmnvrpllnyfeplftwlkdqnkn--sfvgwstdw 610 (805)
722 ...|....+..+++.||+|+.+||+.+|++ --+||..+|
723 T Consensus 560 ~~~G~d~~s~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~ 600 (621)
724 T 6S1Y_A 560 VLTGERKMSADAILEYFDPLYQWLLEENKRLGAHVGWTDSQ 600 (621)
725 T ss_dssp HHHSCCSCCTHHHHHHTHHHHHHHHHHHHHHTCCCSCCCCC
726 T ss_pred HHHCCCCCChHHHHHHHHHHHHHHHHHHHHhCCCCCCCccc
727 Confidence 999988889999999999999999988875 459999775
728
729
730 No 8
731 >4CA5_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.2.1.-, 3.4.15.1); HYDROLASE, ZINC METALLOPEPTIDASE, INHIBITOR BINDING; HET: FUC, 3EF, ACT, NAG; 1.85A {HOMO SAPIENS}
732 Probab=100.00 E-value=3.9e-58 Score=435.55 Aligned_cols=578 Identities=43% Similarity=0.863 Sum_probs=497.1 Template_Neff=10.400
733
734 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
735 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
736 +..++.|++.++.+...+-...+++.|.++++.+++..+....+-.+.+.++.+..++...|..+.+.+-..+-+++.+.
737 T Consensus 5 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 84 (589)
738 T 4CA5_A 5 EAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQ 84 (589)
739 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHHTSCGGGCCCHHHHHHHHHHT
740 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcChhhCCCHHHHHHHHHHH
741 Confidence 56778999999999999999999999999999999999988888888888888777766655333444445566666666
742
743
744 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYE 181 (805)
745 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrplye 181 (805)
746 ..+...|+++.-+++..+...+..+|++..+|.++ .+|+.+.+.+..+|.++-|...|--+|++|+...+..+.+.+.
747 T Consensus 85 ~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~--g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l~ 162 (589)
748 T 4CA5_A 85 DLERAALPAQELEEYNKILLDMETTYSVATVCHPN--GSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYP 162 (589)
749 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCCEECTT--SCEECCCCCCHHHHHHCCCHHHHHHHHHHHCCCCCHHHTTTHH
750 T ss_pred hhhhccCCHHHHHHHHHHHHHHHhhhccceecCCC--CCeecCChhHHHHHhhCCCHHHHHHHHHHHHHHhhHHHHHHHH
751 Confidence 66667888887777788888899999998888775 3567777889999999999999999999999988889999999
752
753
754 Q sp|Q9BYF1|ACE2 182 EYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPIG 260 (805)
755 Q Consensus 182 eyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispig 260 (805)
756 +.+-+++++|+...|.+|.+||..+|+. +.+.+.++..++.++|+|+.+|+|++.++...|.. -++.-+
757 T Consensus 163 ~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~v~~~l~~l~~~v~p~~~~l~~~~~~~~~~~~g~~~~~~~~ 232 (589)
758 T 4CA5_A 163 KYVELINQAARLNGYVDAGDSWRSMYET----------PSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEG 232 (589)
759 T ss_dssp HHHHHHHHHHHHTTCSSHHHHHHGGGCC----------TTHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHCTTTCCTTS
760 T ss_pred HHHHHHHHHHHHcCCCCHHHHHHHccCC----------ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccCCCCC
761 Confidence 9999999999999999999999887732 33457788889999999999999999987554431 133446
762
763
764 Q sp|Q9BYF1|ACE2 261 CLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQ 340 (805)
765 Q Consensus 261 clpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvq 340 (805)
766 -.|+|++|.+|+.-|+++|....||......++++.+..+.+...++++.++.+|-++|+..+...+|+++....++.-.
767 T Consensus 233 ~~p~~~~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~~~~d~~~r~~K~~ 312 (589)
768 T 4CA5_A 233 PIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGR 312 (589)
769 T ss_dssp CEETTSSSSTTSSCCGGGHHHHCSCTTSCCCCHHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSSSC
770 T ss_pred CCcHHHhhhhhhhccccchhhcCCCCCCCCCCcHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHhchhhccCCCCCC
771 Confidence 78999999999999999999999998888888888888888888999999999999999877888899998887777665
772
773
774 Q sp|Q9BYF1|ACE2 341 KAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLK 419 (805)
775 Q Consensus 341 kavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlk 419 (805)
776 ...|||..+++.. ++.||++|...+.+++.|.+||+||..+.+.+..+|++.+.+++-+|+|+++++|+..+.+|.+|+
777 T Consensus 313 ~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~l~ 392 (589)
778 T 4CA5_A 313 EVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLH 392 (589)
779 T ss_dssp CCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHSTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHHHH
780 T ss_pred CceecceeEeCcCCCcEEEEEcCCCCHHHHHHHHHHHHHHHHHHHcCCCCHHHccCCChHHHHHHHHHHHHHhcCHHHHH
781 Confidence 6789999998864 689999999999999999999999999999988999999888999999999999999999999999
782
783
784 Q sp|Q9BYF1|ACE2 420 SIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
785 Q Consensus 420 sigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
786 .++++... +.+.+..++.++.+++..+..+|+.++++.|.+.++.|.+..+.+-+-||+...+.-|+..|.+......|
787 T Consensus 393 ~~~~~~~~-~~~~~~~~~~l~~~~l~~~~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~~~~~y~g~~~~~~~~~~~~~ 471 (589)
788 T 4CA5_A 393 SLNLLSSE-GGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFD 471 (589)
789 T ss_dssp HTTSSCCC-CSCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTSSCTTTHHHHHHHHCCCCCCEECSSCCCTTCCG
790 T ss_pred HcCCCCCC-CCChHHHHHHHHHHHHHHHhhchHHHHHHHHHHHHhCCCCChHhHHHHHHHHHHHHcCCCCCCCCChhhCC
791 Confidence 99987653 22334456788999999999999999999999999999888888999999988888887655444455677
792
793
794 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNM 579 (805)
795 Q Consensus 500 paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknm 579 (805)
796 |++..|......+..|....+..+|+-+.+|+...+.||+|.|++..+.++|.++.++|+.|.+.||.-.++.+.|....
797 T Consensus 472 ~~~~~H~~~~~y~y~Y~~~~~~a~~l~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~~G~~~~~~ell~~~~g~d~~ 551 (589)
798 T 4CA5_A 472 PGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNM 551 (589)
799 T ss_dssp GGGSTTTTTTCCCHHHHHHHHHHHHHHHHHHHHTTCCSCGGGCCCTTCHHHHHHHHHHHHTTTSSCHHHHHHHHHSSCSC
800 T ss_pred ccccccCCCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHHHHHCCCCC
801 Confidence 77888887666778888888999999999999888889999999998899999999999999999999999999998888
802
803
804 Q sp|Q9BYF1|ACE2 580 NVRPLLNYFEPLFTWLKDQNKNS--FVGWST-DWSP 612 (805)
805 Q Consensus 580 nvrpllnyfeplftwlkdqnkns--fvgwst-dwsp 612 (805)
806 ++.+++.+|+||..||+.+|+.. -+||.. .|.|
807 T Consensus 552 ~~~~~~~~~~~l~~~l~~~~~~~~~~~g~~~~~~~~ 587 (589)
808 T 4CA5_A 552 SASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTP 587 (589)
809 T ss_dssp CSHHHHHHHHHHHHHHHHHHHHTTCCCSCSSTTCCC
810 T ss_pred ChHHHHHhHHHHHHHHHHHHHhhCCccCCcccCCCC
811 Confidence 99999999999999999998754 489988 7876
812
813
814 No 9
815 >5A2R_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1); HYDROLASE, ANGIOTENSIN CONVERTING ENZYME, DROSOPHILA; HET: NAG; 1.85A {DROSOPHILA MELANOGASTER}
816 Probab=100.00 E-value=2.8e-56 Score=425.09 Aligned_cols=579 Identities=37% Similarity=0.721 Sum_probs=483.2 Template_Neff=10.300
817
818 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
819 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
820 ++...++|++++.....+-.....+.|.++++.+++..+..+.+..+.+.+.++.......|.++....-..+-+|+.+.
821 T Consensus 5 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 84 (598)
822 T 5A2R_A 5 EIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALT 84 (598)
823 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHGGGSCGGGCSCHHHHHHHHHHH
824 T ss_pred HHHHHHHHHHHHHHHHHHhcHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHhcchhcchhhCCCHHHHHHHHHHH
825 Confidence 35677899999999999999999999999999999988877777888888887766655444422222233455566666
826
827
828 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDN-PQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY 180 (805)
829 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdn-pqeclllepglneimansldynerlwaweswrsevgkqlrply 180 (805)
830 ..+...|+++.-++++..+..++.+|++...|..+. ...++.+.+.+..+|+++-|...|--+|+.|+...+..+.+.+
831 T Consensus 85 ~~~~~~L~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l 164 (598)
832 T 5A2R_A 85 KLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQF 164 (598)
833 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCCBCCSSCTTCCCBCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHHH
834 T ss_pred HhcccCCCHHHHHHHHHHHHHHHHHHhccccCCCCCCCCCcccCCHHHHHHHHcCCCHHHHHHHHHHHHHHccHHHHHHH
835 Confidence 677778888888888888889999999887776432 1245566788999999999999999999999998888999999
836
837
838 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPI 259 (805)
839 Q Consensus 181 eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispi 259 (805)
840 .+.+-+++++|+...|++|.+|+..+++ ...+.+-++..++.|+|+|+.+|+|++.++...|.. -++.-
841 T Consensus 165 ~~l~~~r~~~A~~~Gy~s~~~~~l~~~~----------~~~v~~~l~~l~~~i~~~~~~~~~~~~~~~~~~~~~~~~~~~ 234 (598)
842 T 5A2R_A 165 ERYVELNTKAAKLNNFTSGAEAWLDEYE----------DDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSET 234 (598)
843 T ss_dssp HHHHHHHHHHHHHTTCSSHHHHHHGGGC----------CTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCSS
844 T ss_pred HHHHHHHHHHHHHCCCCCHHHHHHhccC----------CchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCccccCCC
845 Confidence 9999999999999999999999976543 223345566677889999999999999987554321 12334
846
847
848 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
849 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
850 +-+|+|++|++|++-|..+|.+..|+.+++..++++.+....+....+++-++++|-++|+..+..++|++++...|..-
851 T Consensus 235 ~~~p~~l~g~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~w~~~~~~~~~~~ 314 (598)
852 T 5A2R_A 235 GPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTDG 314 (598)
853 T ss_dssp SCEEGGGSSSTTCSCCGGGHHHHCSCTTSCCCCTHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSSC
854 T ss_pred CCCCHHHhhchhhhhhHhhhhhcCCCCCCCCCCchHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChhhhhhhhccCCCCC
855 Confidence 56799999999999999999999999888777888888777788899999999999999999988999999987644321
856
857
858 Q sp|Q9BYF1|ACE2 340 QKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHL 418 (805)
859 Q Consensus 340 qkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhl 418 (805)
860 ....|||.++.+.. ++.||++|...+.+|+.|.+||+||..+.+.+..||++.+++.+.+|+|+++++|++.+.+|.+|
861 T Consensus 315 k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~~L 394 (598)
862 T 5A2R_A 315 RDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHL 394 (598)
863 T ss_dssp CCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHHH
864 T ss_pred CCCccccceEeCcCCCCeEEEecCCCCHHHHHHHHHHHHHHHHHHHccCCChhHccCCChHHHHHHHHHHHHHhcCHHHH
865 Confidence 11358888888774 68999999999999999999999999999999889999999999999999999999999999999
866
867
868 Q sp|Q9BYF1|ACE2 419 KSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYC 498 (805)
869 Q Consensus 419 ksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetyc 498 (805)
870 +.++++. ....+.+..++.++.+++..+..+|+......|++-++.|++....+-+.||+...+.-|++.|.+.+...+
871 T Consensus 395 ~~~~~~~-~~~~~~~~~~~~l~~~~l~~l~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~~~~~~~ 473 (598)
872 T 5A2R_A 395 EKIGLLK-DYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDF 473 (598)
873 T ss_dssp HHTTSSC-SCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTCSCGGGHHHHHHHHHHHHHCEECSSCEETTCC
874 T ss_pred HHcCCCC-ccCCChHHHHHHHHHHHHHHhhhcHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCChhhC
875 Confidence 9999874 333444567788899999999999998888999999999988778899999999999989876655555557
876
877
878 Q sp|Q9BYF1|ACE2 499 DPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALEN 572 (805)
879 Q Consensus 499 dpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlalen 572 (805)
880 ++++..|+..+..++.|....+..+|+-+.+|+...+ .||+|.||...+.++|+++.++|+.|.+.||.-.++.
881 T Consensus 474 ~~~~~~hi~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~G~s~~~~e~~~~ 553 (598)
882 T 5A2R_A 474 DAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEA 553 (598)
883 T ss_dssp CGGGSHHHHTTCCCHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHH
884 T ss_pred CCccceeecCCchHHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHHH
885 Confidence 7888888775556788888889999999998886544 6799999999889999999999999999999999999
886
887
888 Q sp|Q9BYF1|ACE2 573 VVGAKNMNVRPLLNYFEPLFTWLKDQNKNSF--VGWSTDWS 611 (805)
889 Q Consensus 573 vvgaknmnvrpllnyfeplftwlkdqnknsf--vgwstdws 611 (805)
890 ..|..-.+..+++.+|.|+-.||+.+|+..- +||..+|.
891 T Consensus 554 ~~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~~w~~~~~ 594 (598)
892 T 5A2R_A 554 FNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNK 594 (598)
893 T ss_dssp HHSCCSCCSHHHHHHHHHHHHHHHHHHHHTTCCCSCCCCSC
894 T ss_pred HhCCCCCChHHHHHHHHHHHHHHHHhHHhcCCcCCccCCCc
895 Confidence 9999878999999999999999999987665 99999873
896
897
898 No 10
899 >4ASR_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1), BRADYKININ; HYDROLASE, ZINC METALLOPROTEASE, SUBSTRATE RECOGNITION; HET: MAN, NAG, FLC, BMA; 1.9A {DROSOPHILA MELANOGASTER}
900 Probab=100.00 E-value=2.9e-56 Score=426.35 Aligned_cols=578 Identities=37% Similarity=0.724 Sum_probs=486.1 Template_Neff=10.200
901
902 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
903 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
904 +.+...||..++.....+-....++.|.++++.+++..+..+.+..+.+.+..+..+.+..|.++...+-..+-+|+.+.
905 T Consensus 6 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 85 (598)
906 T 4ASR_A 6 EIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALT 85 (598)
907 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHHHGGGSCGGGCSCHHHHHHHHHHH
908 T ss_pred HHHHHHHHHHHHHHHHHHhCHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHhcchhcchhcCCCHHHHHHHHHHH
909 Confidence 46678899999999999999999999999999999988888788888888888777666555533333334555666666
910
911
912 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDN-PQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY 180 (805)
913 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdn-pqeclllepglneimansldynerlwaweswrsevgkqlrply 180 (805)
914 ..+...|+++.-++++..+..+..+|++...|.... ..+++.+.|.+..+|.++-|...|--+|++|++..+..+.+++
915 T Consensus 86 ~~~~~~L~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~~l 165 (598)
916 T 4ASR_A 86 KLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQF 165 (598)
917 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCCBCCSSCTTCCCBCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHHH
918 T ss_pred HhccccCCHHHHHHHHHHHHHHHHHhhccccCCCCCCCCccccCCHHHHHHHHcCCCHHHHHHHHHHHHHHhcHHHHHHH
919 Confidence 666678888888888888899999999887776432 1255566788999999999999999999999998888999999
920
921
922 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPI 259 (805)
923 Q Consensus 181 eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispi 259 (805)
924 .+.+-+++++|+...|.+|.+|+..++ +...+.+-++..++.++|+++.+|+|+|.++...|.. .+++-
925 T Consensus 166 ~~lv~~r~~~A~~~Gy~s~~~~~l~~~----------~~~~v~~~l~~l~~~i~~~~~~l~~~~~~~~~~~~~~~~~~~~ 235 (598)
926 T 4ASR_A 166 ERYVELNTKAAKLNNFTSGAEAWLDEY----------EDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSET 235 (598)
927 T ss_dssp HHHHHHHHHHHHHTTCSSHHHHHHGGG----------CCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCSS
928 T ss_pred HHHHHHHHHHHHHCCCCCHHHHHHhcc----------CCccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccCCC
929 Confidence 999999999999999999999997654 2334445666778889999999999999987554432 13334
930
931
932 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
933 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
934 +-+|+|++|++|++-|..+|.+..|+...+..++++.++.+.+...++|+-++++|-++|+..+..+||++++...+..
935 T Consensus 236 ~~~p~~l~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~w~~~~~~~~~~- 314 (598)
936 T 4ASR_A 236 GPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTD- 314 (598)
937 T ss_dssp SCEEGGGSSSTTSSCCGGGHHHHCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCSS-
938 T ss_pred CCCcHHHccccchhcchhhhhhcCCCCCCCCCCccHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChHHhhhhhccCCCC-
939 Confidence 6689999999999999999999999987776677777878888889999999999999999988889999998765432
940
941
942 Q sp|Q9BYF1|ACE2 340 QK-AVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKH 417 (805)
943 Q Consensus 340 qk-avchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkh 417 (805)
944 .| ..|||.++++.. ++.||++|+..+.+|+.|.+||+||..+.+.+..+|++.+.+.+.+|+|+++++|++.+.+|.+
945 T Consensus 315 ~k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~d~~E~~s~~~e~~~~~~~~ 394 (598)
946 T 4ASR_A 315 GRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKH 394 (598)
947 T ss_dssp SCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHHTTSCGGGSSCSSHHHHHHHHHHHHHHHTSHHH
948 T ss_pred CCCCcccchhhhccCCCCEEEEecCCCCHHHHHHHHHHHHHHHHHHHccCCChHHccCCChHHHHHHHHHHHHHhcCHHH
949 Confidence 22 368888888875 5899999999999999999999999999999988999999889999999999999999999999
950
951
952 Q sp|Q9BYF1|ACE2 418 LKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
953 Q Consensus 418 lksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
954 |+.++++. ..+...+..++.++++++..+..+|+..+...|++-++.|++..+.+.+.||+...+..|+..|.+.++..
955 T Consensus 395 L~~~~~~~-~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~l~~~~~g~~~~~~~~~~~ 473 (598)
956 T 4ASR_A 395 LEKIGLLK-DYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKD 473 (598)
957 T ss_dssp HHHTTSSC-SCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTCSCGGGHHHHHHHHCCCCCCEECSSCEETTC
958 T ss_pred HHHcCCCC-ccCCChHHHHHHHHHHHHHHhhhhHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCChhh
959 Confidence 99999864 33334455678888999999999999888899999999998877889999999999998987665555555
960
961
962 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALE 571 (805)
963 Q Consensus 498 cdpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlale 571 (805)
964 .+|.+..|+..+..+..|....+..+|+-+.+|+.+.+ +||+|.|+...+.++|.++-++|..|.+.||.-.++
965 T Consensus 474 ~~~~~~~h~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~l~~G~s~~~~el~~ 553 (598)
966 T 4ASR_A 474 FDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALE 553 (598)
967 T ss_dssp CCGGGSHHHHTTCCSHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHH
968 T ss_pred CCCccceeecCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHH
969 Confidence 56777778765555788888888999999999887554 689999999988999999999999999999999999
970
971
972 Q sp|Q9BYF1|ACE2 572 NVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGWSTDWS 611 (805)
973 Q Consensus 572 nvvgaknmnvrpllnyfeplftwlkdqnkns--fvgwstdws 611 (805)
974 ...|..-.+..+++.+|+|+-.||+.+|+.. -+||.++|-
975 T Consensus 554 ~~~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~ 595 (598)
976 T 4ASR_A 554 AFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNK 595 (598)
977 T ss_dssp HHHSCCSCCSHHHHHHHHHHHHHHHHHHHHTTCCCSCCCCCS
978 T ss_pred HHhCCCCCChHHHHHHHHHHHHHHHHhhhhcCccccccCCCc
979 Confidence 9999988899999999999999999988755 499999884
980
981
982 No 11
983 >4CA7_A ANGIOTENSIN-CONVERTING ENZYME (E.C.3.4.15.1); HYDROLASE, ZINC METALLOPEPTIDASE, INHIBITOR BINDING; HET: MAN, NAG, 3EF, BMA; 1.82A {DROSOPHILA MELANOGASTER}
984 Probab=100.00 E-value=3.2e-56 Score=426.00 Aligned_cols=578 Identities=37% Similarity=0.724 Sum_probs=485.3 Template_Neff=10.200
985
986 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
987 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
988 +.+...||..++.....+-....++.|.++++.+++..+..+.+..+.+.+..+..+.+..|.++...+-..+-+|+.+.
989 T Consensus 6 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~ 85 (598)
990 T 4CA7_A 6 EIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVASDTTKFQWRSYQSEDLKRQFKALT 85 (598)
991 T ss_dssp GC-CHHHHHHHHHHHHHHHHHHHHHHHHHHTSCCHHHHHHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCHHHHHHHHHHH
992 T ss_pred HHHHHHHHHHHHHHHHHHhCHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHhcchhcchhcCCCHHHHHHHHHHH
993 Confidence 46678899999999999999999999999999999988888788888888888777666555533333334555666666
994
995
996 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDN-PQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLY 180 (805)
997 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdn-pqeclllepglneimansldynerlwaweswrsevgkqlrply 180 (805)
998 ..+...|+++.-++++..+..+..+|++...|.... ..+++.+.|.+..+|.++-|...|--+|++|++..+..+.+++
999 T Consensus 86 ~~~~~~L~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~g~~~~l~~~~~~~l~~~~~~~~R~~~~~~~~~~~~~~~~~~l 165 (598)
1000 T 4CA7_A 86 KLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKDSTKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQF 165 (598)
1001 T ss_dssp CCGGGGSCHHHHHHHHHHHHHHHHHHHHCEECCSSCTTCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHTGGGHHHH
1002 T ss_pred HhccccCCHHHHHHHHHHHHHHHHHhhccccCCCCCCCCccccCCHHHHHHHHcCCCHHHHHHHHHHHHHHhcHHHHHHH
1003 Confidence 666678888888888888899999999887776432 1255566788999999999999999999999988778899999
1004
1005
1006 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YISPI 259 (805)
1007 Q Consensus 181 eeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yispi 259 (805)
1008 .+.+-+++++|+...|.+|.+|+..++ +...+.+-++..++.++|+++.+|+|+|.++...|.. .+++-
1009 T Consensus 166 ~~lv~~r~~~A~~~Gy~s~~~~~l~~~----------~~~~v~~~l~~l~~~i~~~~~~l~~~~~~~~~~~~~~~~~~~~ 235 (598)
1010 T 4CA7_A 166 ERYVELNTKAAKLNNFTSGAEAWLDEY----------EDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSET 235 (598)
1011 T ss_dssp HHHHHHHHHHHHHTTCSSHHHHHHGGG----------CCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTSCSS
1012 T ss_pred HHHHHHHHHHHHHCCCCCHHHHHHhcc----------CCccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccCCC
1013 Confidence 999999999999999999999997654 2334445666778889999999999999987554432 13334
1014
1015
1016 Q sp|Q9BYF1|ACE2 260 GCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNV 339 (805)
1017 Q Consensus 260 gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnv 339 (805)
1018 +-+|+|++|++|++-|..+|.+..|+...+..++++.++.+.+...++|+-++++|-++|+..+..+||++++...+..
1019 T Consensus 236 ~~~p~~l~~~~~~~~w~~~~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~w~~~~~~~~~~- 314 (598)
1020 T 4CA7_A 236 GPIPMHLLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQDFWDKSIIEKPTD- 314 (598)
1021 T ss_dssp SCEEGGGSSSTTCSCCGGGHHHHCSCTTSCCCCCHHHHHHTTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCCS-
1022 T ss_pred CCCcHHHccccchhcchhhhhhcCCCCCCCCCCccHHHHHCCCCHHHHHHHHHHHHHhCCCCCCChHHhhhhhccCCCC-
1023 Confidence 6689999999999999999999999987776677777878888889999999999999999988889999998765432
1024
1025
1026 Q sp|Q9BYF1|ACE2 340 QK-AVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKH 417 (805)
1027 Q Consensus 340 qk-avchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkh 417 (805)
1028 .| ..|||.++++.. ++.||++|+..+.+|+.|.+||+||..+.+.+..+|++.+.+.+.+|+|+++++|++.+.+|.+
1029 T Consensus 315 ~k~~~~~~~~~~~~~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~d~~E~~s~~~e~~~~~~~~ 394 (598)
1030 T 4CA7_A 315 GRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQYQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKH 394 (598)
1031 T ss_dssp SCCCCCSCEEEECSSSSCEEEECCCCSSHHHHHHHHHHHHHHHHHHHTTTSCGGGCSCSSHHHHHHHHHHHHHHHTSHHH
1032 T ss_pred CCCCcccchhhhccCCCCEEEEecCCCCHHHHHHHHHHHHHHHHHHHccCCChHHccCCChHHHHHHHHHHHHHhcCHHH
1033 Confidence 22 368888888875 5899999999999999999999999999999988999999889999999999999999999999
1034
1035
1036 Q sp|Q9BYF1|ACE2 418 LKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
1037 Q Consensus 418 lksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
1038 |+.++++. ..+...+..++.++++++..+..+|+..+...|++-++.|++..+.+.+.||+...+..|+..|.+.++..
1039 T Consensus 395 L~~~~~~~-~~~~~~~~~~~~l~~~~l~~~~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~l~~~~~g~~~~~~~~~~~ 473 (598)
1040 T 4CA7_A 395 LEKIGLLK-DYVRDDEARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKD 473 (598)
1041 T ss_dssp HHHTTCSC-SCCCCHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHTTCSCGGGHHHHHHHHCCCCCCEECSSCEETTC
1042 T ss_pred HHHcCCCC-ccCCChHHHHHHHHHHHHHHhhhhHHHHHHHHHHHHHHcCCCCHHHHHHHHHHHHHHHcCCCCCCCCChhh
1043 Confidence 99999864 33334455678888999999999999888899999999998877889999999999998987665555555
1044
1045
1046 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKH------EGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALE 571 (805)
1047 Q Consensus 498 cdpaslfhvsndysfiryytrtlyqfqfqealcqaakh------egplhkcdisnsteagqklfnmlrlgksepwtlale 571 (805)
1048 .+|.+..|+..+..+..|....+..+|+-+.+|+.+.+ +||+|.|+...+.++|.++-++|..|.+.||.-.++
1049 T Consensus 474 ~~~~~~~h~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~~~~~l~~G~s~~~~el~~ 553 (598)
1050 T 4CA7_A 474 FDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLSMGASKPWPDALE 553 (598)
1051 T ss_dssp CCGGGSHHHHTTCCCHHHHHHHHHHHHHHHHHHHHTTCCCTTCTTSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHH
1052 T ss_pred CCCccceeecCCchhHHHHHHHHHHHHHHHHHHHHcCCCCCCCCCCCchhCCccCCHHHHHHHHHHHhcCCCCCHHHHHH
1053 Confidence 56777778765555788888888999999999887554 689999999988999999999999999999999999
1054
1055
1056 Q sp|Q9BYF1|ACE2 572 NVVGAKNMNVRPLLNYFEPLFTWLKDQNKNS--FVGWSTDWS 611 (805)
1057 Q Consensus 572 nvvgaknmnvrpllnyfeplftwlkdqnkns--fvgwstdws 611 (805)
1058 ...|..-.+..+++.+|+|+-.||+.+|+.. -+||.++|-
1059 T Consensus 554 ~~~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~gw~~~~~ 595 (598)
1060 T 4CA7_A 554 AFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTTSNK 595 (598)
1061 T ss_dssp HHHSCCSCCTHHHHHHHHHHHHHHHHHHHHTTCCCSCCCCCS
1062 T ss_pred HHhCCCCCChHHHHHHHHHHHHHHHHhhhhcCccccccCCCc
1063 Confidence 9999988899999999999999999988755 499999884
1064
1065
1066 No 12
1067 >2C6F_A ANGIOTENSIN-CONVERTING ENZYME, SOMATIC ISOFORM (E.C.3.4.15.1); HYDROLASE, ANGIOTENSIN-I CONVERTING ENZYME, N; HET: ACT, GOL, NAG; 3.01A {HOMO SAPIENS}
1068 Probab=100.00 E-value=2.3e-52 Score=400.71 Aligned_cols=579 Identities=43% Similarity=0.828 Sum_probs=477.2 Template_Neff=10.200
1069
1070 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMY-P--LQEIQNLTVKLQLQ 98 (805)
1071 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmy-p--lqeiqnltvklqlq 98 (805)
1072 +++...|+++++.....+--..+.+.|.++++++++..+....+..+.+.|..+.+....-. . +++...-..+-.|+
1073 T Consensus 14 ~~~~~~~l~~~~~~~~~l~~~~~~a~~~~~~d~~~~~~~~~~~~~~~~~~~~~~l~~~~~~l~~~~~~~~~~~~~~~~l~ 93 (612)
1074 T 2C6F_A 14 EAGAQLFAQSYNSSAEQVLFQSVAASWAHDTNITAENARRQEEAALLSQEFAEAWGQKAKELYEPIWQNFTDPQLRRIIG 93 (612)
1075 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTSCSCHHHHHHHH
1076 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcchHhhCCCHHHHHHHH
1077 Confidence 46677899999999999999999999999999998877666666666666655444321110 0 11111112233344
1078
1079
1080 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVGKQLRP 178 (805)
1081 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevgkqlrp 178 (805)
1082 .+...+...|+++..+++..+...++.+|++-.+|..+.+.+|+.+.+.+..+|.++-|...|--+|++|+...+..+.+
1083 T Consensus 94 ~l~~~~~~~L~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~l~~~~d~~~R~~~~~~~~~~~~~~~~~ 173 (612)
1084 T 2C6F_A 94 AVRTLGSANLPLAKRQQYNALLSNMSRIYSTAKVCLPNKTATCWSLDPDLTNILASSRSYAMLLFAWEGWHNAAGIPLKP 173 (612)
1085 T ss_dssp HHSCCGGGGSCHHHHHHHHHHHHHHHHHHHHCEECCSSCCCCCEECCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
1086 T ss_pred HHHHhhcccCCHHHHHHHHHHHHHHHHHHHhccccCCCCCCCcccCChhHHHHHhhCCCHHHHHHHHHHHHHHhCcccHH
1087 Confidence 45455556788887777888888999999999988777666788888899999999999999999999999877788999
1088
1089
1090 Q sp|Q9BYF1|ACE2 179 LYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPS-YIS 257 (805)
1091 Q Consensus 179 lyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnayps-yis 257 (805)
1092 ++.+.+-+++++|+...|++|.+|+..++.. ....+-++...+.++|++..+|+|++.++...+-. .++
1093 T Consensus 174 ~l~~lv~~r~~~A~~~Gy~s~~~~~l~~~~~----------~~~~~~l~~l~~~~~~~~~~~~~~~~~~~~~~~g~~~~~ 243 (612)
1094 T 2C6F_A 174 LYEDFTALSNEAYKQDGFTDTGAYWRSWYNS----------PTFEDDLEHLYQQLEPLYLNLHAFVRRALHRRYGDRYIN 243 (612)
1095 T ss_dssp HHHHHHHHHHHHHHTTTCSSHHHHHHGGGCC----------TTHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTTCC
1096 T ss_pred HHHHHHHHHHHHHHHcCCCCHHHHHHHhhCC----------CcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcccccC
1097 Confidence 9999999999999999999999999776542 23345566777888999999999999987554321 233
1098
1099
1100 Q sp|Q9BYF1|ACE2 258 PIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPG 337 (805)
1101 Q Consensus 258 pigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpg 337 (805)
1102 .-+-+|.|++|++|+..|+.+|...+|+.++...++++++....+...++++.++++|-++|+..+...+|+++....||
1103 T Consensus 244 ~~~~lp~d~~~~~~~~~~~~~~~~~~p~~~~~~~~i~~~~~~~~~~~~~~~~~~~~~~~~lg~~~~~~~~w~~~~~~r~~ 323 (612)
1104 T 2C6F_A 244 LRGPIPAHLLGDMWAQSWENIYDMVVPFPDKPNLDVTSTMLQQGWNATHMFRVAEEFFTSLELSPMPPEFWEGSMLEKPA 323 (612)
1105 T ss_dssp TTSCEETTSSSSTTCSCCGGGHHHHCSSCSSCCSCTHHHHHHHTCCHHHHHHHHHHHHHHTTCCCCCHHHHHHCBCSCCS
1106 T ss_pred CCCCCcHHHccCcchhcchhhhhhhCCCCCCCCCCCcHHHHhCCCCHHHHHHHHHHHHHhcCCCCCChhhhccccccCCC
1107 Confidence 34456999999999999999999999998777677778877777888899999999999999998888999999877777
1108
1109
1110 Q sp|Q9BYF1|ACE2 338 NVQKAVCHPTAWDLGK-GDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPK 416 (805)
1111 Q Consensus 338 nvqkavchptawdlgk-gdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpk 416 (805)
1112 .-....||+.++++.. ++.||++|...+.+|+.|.+||+||..+.+.+..+|++.++.++.+|+|+++++|+..+.+|.
1113 T Consensus 324 K~~~~~~~a~~~~~~~~~~~~i~~~~~~~~~~~~tl~HElGHa~h~~~~~~~~~~~~~~~~~~~~E~~s~~~e~~~~~~~ 403 (612)
1114 T 2C6F_A 324 DGREVVCHASAWDFYNRKDFRIKQCTRVTMDQLSTVHHEMGHIQYYLQYKDLPVSLRRGANPGFHEAIGDVLALSVSTPE 403 (612)
1115 T ss_dssp SSCCCCCSCEEEECSSSSCEEEECCCCSCHHHHHHHHHHHHHHHHHHHHTTSCGGGCSCSSHHHHHHHHHHHHHHHHSHH
1116 T ss_pred CCCcceecchhhhCcCCCcEEEEEcCCCCHHHHHHHHHHHHHHHHHHHccCCCHHHccCCChHHHHHHHHHHHHHhcCHH
1117 Confidence 6655678888887764 689999999999999999999999999999988899998888889999999999999999999
1118
1119
1120 Q sp|Q9BYF1|ACE2 417 HLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDET 496 (805)
1121 Q Consensus 417 hlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdet 496 (805)
1122 .|+.++++.. .+...+..++.++++++..+..+|+..+++.|+|.++.|.++.+.+-+.||+...+..|...|.+.+++
1123 T Consensus 404 ~L~~~~~~~~-~~~~~~~~~~~l~~~~l~~l~~l~~~~~~d~~~~~~~~~~~~~~~l~~~~~~l~~~y~g~~~~~~~~~~ 482 (612)
1124 T 2C6F_A 404 HLHKIGLLDR-VTNDTESDINYLLKMALEKIAFLPFGYLVDQWRWGVFSGRTPPSRYNFDWWYLRTKYQGICPPVTRNET 482 (612)
1125 T ss_dssp HHHHTTSCCC-CCCSHHHHHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHTSSCGGGHHHHHHHHHHHHHCEECSSCCCTT
1126 T ss_pred HHHHcCCCCC-CCCCcHHHHHHHHHHHHHHhhccHHHHHHHHHHHHHhcCCCChhhHHHHHHHHHHHHcCCCCCCCCChh
1127 Confidence 9999988753 222234456788899999999999999999999999999888888999999988888887655555666
1128
1129
1130 Q sp|Q9BYF1|ACE2 497 YCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNMLRLGKSEPWTLALENVVGA 576 (805)
1131 Q Consensus 497 ycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvga 576 (805)
1132 ..||++..|+..+...+.|....+..+|+-+.+|+...+.+|+|+||+..+.++|+++.++|+.|.+.+|.-.++...|.
1133 T Consensus 483 ~~~~~~~~h~~~~~~yy~Y~~s~~~a~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~L~~G~s~~~~el~~~~~G~ 562 (612)
1134 T 2C6F_A 483 HFDAGAKFHVPNVTPYIRYFVSFVLQFQFHEALCKEAGYEGPLHQCDIYRSTKAGAKLRKVLQAGSSRPWQEVLKDMVGL 562 (612)
1135 T ss_dssp CCGGGGSTTTTTTCCCHHHHHHHHHHHHHHHHHHHHHTCCSCGGGCCCTTCHHHHHHHHHHHTTTTSSCHHHHHHHHHSC
1136 T ss_pred cCCcccceecCCChhhHHHHHHHHHHHHHHHHHHHHcCCCCChhhCCccCCHHHHHHHHHHHhcCCCCCHHHHHHHHhCC
1137 Confidence 67788888876434467888888999999999999878889999999999999999999999999999999999999998
1138
1139
1140 Q sp|Q9BYF1|ACE2 577 KNMNVRPLLNYFEPLFTWLKDQNKNSF--VGWSTDWS 611 (805)
1141 Q Consensus 577 knmnvrpllnyfeplftwlkdqnknsf--vgwstdws 611 (805)
1142 ...+..+++.+|+++..||+.+|++.- +||..+|-
1143 T Consensus 563 d~~~~~~~~~~~~~l~~~l~~~~~~~~~~~g~~~~~~ 599 (612)
1144 T 2C6F_A 563 DALDAQPLLKYFQPVTQWLQEQNQQNGEVLGWPEYQW 599 (612)
1145 T ss_dssp SSCCSHHHHHHSHHHHHHHHHHHHHTTCCSSCSSTTC
1146 T ss_pred CCCCcHHHHHHHHHHHHHHHHHHHhcCCccCCCccCC
1147 Confidence 778889999999999999999988665 99997663
1148
1149
1150 No 13
1151 >5GIV_E Carboxypeptidase; M32 carboxypeptidase, Cobalt, Metallopeptidase, HYDROLASE; 2.4A {Deinococcus radiodurans str. R1}
1152 Probab=100.00 E-value=4.3e-52 Score=399.56 Aligned_cols=474 Identities=18% Similarity=0.185 Sum_probs=379.1 Template_Neff=9.400
1153
1154 Q sp|Q9BYF1|ACE2 19 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 98 (805)
1155 Q Consensus 19 stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlq 98 (805)
1156 ++.+..+.+||.+.+.+...+-++.++++|++.|++++++.+.....- ++|++. ..+.+.+-.++-+|.
1157 T Consensus 3 ~~~~~~~~~~L~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~~~~~~----------~~l~~~-~~~~~~~~~~~~~l~ 71 (503)
1158 T 5GIV_E 3 TTRQDTQWQQLTEHWQELADFGGIEALLGWDQSTFLPAGAAEDRARQQ----------SLLAGL-RHARATDAGYGKLLD 71 (503)
1159 T ss_dssp ----CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHH----------HHHHHH-HHHHHSCHHHHHHHH
1160 T ss_pred ccchHHHHHHHHHHHHHHHHHhcHHHHHHHHHHcCCCcchHHHHHHHH----------HHHHHH-HHHhhcCHHHHHHHH
1161 Confidence 567788999999999999999999999999999999998876544333 233332 133455666777777
1162
1163
1164 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG-KQLR 177 (805)
1165 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg-kqlr 177 (805)
1166 .++.. +.++++. ..++..|..+|..++ .++|.+.++|+++.+..+ ++|..||.+.+ +.++
1167 T Consensus 72 ~l~~~--~~l~~~~----~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~ 132 (503)
1168 T 5GIV_E 72 AASSR--SDLSPEQ----ARMVQVARQDFEKAT-----------RIPAEFVREFSGHVGQSY--SAWTEARPANDFGRMV 132 (503)
1169 T ss_dssp HHHTC--SSCCHHH----HHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHTTTTCHHHHH
1170 T ss_pred HHhcC--CCCCHHH----HHHHHHHHHHHHHhc-----------CCCHHHHHHHHhchhhHH--HHHHHHHHhCChhHhH
1171 Confidence 77655 2344433 344677888887765 467899999999998876 89999999977 8999
1172
1173
1174 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYE-DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1175 Q Consensus 178 plyeeyvvlknemaranhye-dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1176 |+|+++|-|+|+.|+.+.|+ ++.|||...|+- |...++++..|++|+|+|..||++||.+-
1177 T Consensus 133 ~~~~~~v~l~~~~A~~~g~~~~~yd~~l~~ye~----------~~~~~~l~~l~~~i~~~~~~l~~~v~~~~-------- 194 (503)
1178 T 5GIV_E 133 PYLEKTLDLSLQAASYFPEFGDPLDYYINESDE----------GMTAEQVGQVFAELRAALVPLADAVIAAG-------- 194 (503)
1179 T ss_dssp HHHHHHHHHHHHHHHTCTTCSSHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHHHC--------
1180 T ss_pred HHHHHHHHHHHHHHhhCCCCCCHHHHHHHhcCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHHcC--------
1181 Confidence 99999999999999999998 999999876653 44568899999999999999999999851
1182
1183
1184 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1185 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1186 .|+ | .+..+.++..++++.+++||.++|++... +. .|
1187 T Consensus 195 ~~~---~--------------------------------~~~~~~~~~~~~~~~~~~~~~~lG~~~~~------~~-~d- 231 (503)
1188 T 5GIV_E 195 APR---T--------------------------------DFLGRGFAQERQLAFGERVIRDYGYDFRR------GR-QD- 231 (503)
1189 T ss_dssp CCC---C--------------------------------GGGGSCCCHHHHHHHHHHHHHHHTCCGGG------CC-EE-
1190 T ss_pred CCC---c--------------------------------hhhcCCCCHHHHHHHHHHHHHHhCCCccc------Cc-cc-
1191 Confidence 010 1 12334455677889999999999998621 11 11
1192
1193
1194 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAAQ--PFLLRNGANEGFHEAVGEIMSLSA 412 (805)
1195 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaaq--pfllrnganegfheavgeimslsa 412 (805)
1196 ..|||.+|+++.+|+||.||.+++ ++|+.+.|||+||++|.+.+..+ +..++.+++.+|||+++..|.+..
1197 T Consensus 232 -----~~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~ 306 (503)
1198 T 5GIV_E 232 -----LTHHPFMTRLGGHDVRITTRVKEQDPTDALYSTLHEAGHALYEQGVDAAFLGTPLGGGVSAGVHESQSRLWENLV 306 (503)
1199 T ss_dssp -----ECSSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHHTSCTTTTTSTTSSCSCHHHHHHHHHCCCCCC
1200 T ss_pred -----cCCCccccCCCCCcEEEEeecCCCChHHHHHHHHHHHHHHHHHcCCCHHHcCCCCCCccchHHHHHHHHHHHHhh
1201 Confidence 599999999988999999999999 69999999999999999988764 345578899999999999999999
1202
1203
1204 Q sp|Q9BYF1|ACE2 413 AT---------PKHLKSIGLLSPDF-QEDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWW 478 (805)
1205 Q Consensus 413 at---------pkhlksigllspdf-qednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkww 478 (805)
1206 .+ |++++.+|.+-.+. .++-...+| .+++.++.-+-.+|+.++..+|+|-+|.|+++.+++.+.||
1207 T Consensus 307 ~~~~~f~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~g~~~~~~l~~~w~ 386 (503)
1208 T 5GIV_E 307 GRSRAFWAAYFGDWRDTFPEQLAGVTEEEMYRAVNTVSRSLIRTDADELTYNLHVITRFELEREMLAGKLAVRDLADAWH 386 (503)
1209 T ss_dssp TTSHHHHHHHHHHHHHHSTTTTTTCCHHHHHHHTTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHTTSSCGGGHHHHHH
1210 T ss_pred cCCHHHHHHHHHHHHHHCcHHhCCCCHHHHHHHHHhhCHHHhHHHhhhhhhcHHHHHHHHHHHHHhcCCCCHHHHHHHHH
1211 Confidence 99 99999988542222 222333444 45677777778888899999999999999999999999999
1212
1213
1214 Q sp|Q9BYF1|ACE2 479 EMKREIVGVVEPVPHDETYCDPASLFHVSNDY---SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN--STEAGQK 553 (805)
1215 Q Consensus 479 emkreivgvvepvphdetycdpaslfhvsndy---sfiryytrtlyqfqfqealcqaakhegplhkcdisn--steagqk 553 (805)
1216 ++.++..|+..|. +...|+ ...|++.++ .|++|....++++|+.+++|+... .+|+| +.+ ..++|..
1217 T Consensus 387 ~~~~~y~G~~~~~--~~~~~~--~~~h~~~~~~~~y~~~Y~~g~i~a~ql~~~~~~~~~---~~~~~-~~~~~~~~~~~~ 458 (503)
1218 T 5GIV_E 387 AAYEQNLGLRAPS--DVDGAL--QDVHWYFGPIGGSFQGYTIGNVLSAQFYAAAEAANP---GLEAD-FARKDFSRLHGW 458 (503)
1219 T ss_dssp HHHHHHHSCCCSS--STTTTT--SCSGGGSSCSSSSSHHHHHHHHHHHHHHHHHHHHST---THHHH-HHTTCCHHHHHH
1220 T ss_pred HHHHHHhCCCCCC--CCCCCc--ccccccccCcccCCHHHHHHHHHHHHHHHHHHHhCC---ChHHH-hhcCChHHHHHH
1221 Confidence 9999999987553 334454 467888765 479999999999999999998764 49999 863 4688999
1222
1223
1224 Q sp|Q9BYF1|ACE2 554 LF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1225 Q Consensus 554 lf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1226 |- ++++.|.+.||.-.++.+.|. .++..++++||+|+++||-+
1227 T Consensus 459 l~~~il~~G~~~~~~ell~~~~g~-~ls~~~~l~y~~~~~~~~~~ 502 (503)
1228 T 5GIV_E 459 LRENVYRHGRRWTPGELIERATGQ-ALTAGPYLKYLRGKYGELYG 502 (503)
1229 T ss_dssp HCCCCCTTTTSSCHHHHHHHHHSS-SSCSHHHHHHHHHHHHHHHC
1230 T ss_pred HHHchHhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1231 Confidence 94 999999999999999999996 89999999999999999864
1232
1233
1234 No 14
1235 >5GIV_F Carboxypeptidase; M32 carboxypeptidase, Cobalt, Metallopeptidase, HYDROLASE; 2.4A {Deinococcus radiodurans str. R1}
1236 Probab=100.00 E-value=4.3e-52 Score=399.56 Aligned_cols=474 Identities=18% Similarity=0.185 Sum_probs=381.7 Template_Neff=9.400
1237
1238 Q sp|Q9BYF1|ACE2 19 STIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQ 98 (805)
1239 Q Consensus 19 stieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlq 98 (805)
1240 ++.+..+.+||.+.+.+...+-++.++++|++.|++++++.+.....- ++|++. ..+.+.+-.++-+|.
1241 T Consensus 3 ~~~~~~~~~~L~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~~~~~~----------~~l~~~-~~~~~~~~~~~~~l~ 71 (503)
1242 T 5GIV_F 3 TTRQDTQWQQLTEHWQELADFGGIEALLGWDQSTFLPAGAAEDRARQQ----------SLLAGL-RHARATDAGYGKLLD 71 (503)
1243 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHH----------HHHHHH-HHHHHTCHHHHHHHH
1244 T ss_pred ccchHHHHHHHHHHHHHHHHHhcHHHHHHHHHHcCCCcchHHHHHHHH----------HHHHHH-HHHhhcCHHHHHHHH
1245 Confidence 567788999999999999999999999999999999998876544333 233332 133455666777777
1246
1247
1248 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG-KQLR 177 (805)
1249 Q Consensus 99 alqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg-kqlr 177 (805)
1250 .++.. +.++++. ..++..|..+|..++ .++|.+.++|+++.+..+ ++|..||.+.+ +.++
1251 T Consensus 72 ~l~~~--~~l~~~~----~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~ 132 (503)
1252 T 5GIV_F 72 AASSR--SDLSPEQ----ARMVQVARQDFEKAT-----------RIPAEFVREFSGHVGQSY--SAWTEARPANDFGRMV 132 (503)
1253 T ss_dssp HHHHC--SCCCHHH----HHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHTTTTCHHHHH
1254 T ss_pred HHhcC--CCCCHHH----HHHHHHHHHHHHHhc-----------CCCHHHHHHHHhchhhHH--HHHHHHHHhCChhHhH
1255 Confidence 77655 2344433 344677888887765 467899999999998876 89999999977 8999
1256
1257
1258 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYE-DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1259 Q Consensus 178 plyeeyvvlknemaranhye-dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1260 |+|+++|-|+|+.|+.+.|+ ++.|||...|+- |...++++..|++|+|+|..||++||.+-
1261 T Consensus 133 ~~~~~~v~l~~~~A~~~g~~~~~yd~~l~~ye~----------~~~~~~l~~l~~~i~~~~~~l~~~v~~~~-------- 194 (503)
1262 T 5GIV_F 133 PYLEKTLDLSLQAASYFPEFGDPLDYYINESDE----------GMTAEQVGQVFAELRAALVPLADAVIAAG-------- 194 (503)
1263 T ss_dssp HHHHHHHHHHHHHHHTCTTSSSHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHHHC--------
1264 T ss_pred HHHHHHHHHHHHHHhhCCCCCCHHHHHHHhcCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHHcC--------
1265 Confidence 99999999999999999998 999999876653 44568899999999999999999999851
1266
1267
1268 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1269 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1270 .|+ | .+..+.++..++++.+++||.++|++... +. .|
1271 T Consensus 195 ~~~---~--------------------------------~~~~~~~~~~~~~~~~~~~~~~lG~~~~~------~~-~d- 231 (503)
1272 T 5GIV_F 195 APR---T--------------------------------DFLGRGFAQERQLAFGERVIRDYGYDFRR------GR-QD- 231 (503)
1273 T ss_dssp CCC---C--------------------------------GGGGSCCCHHHHHHHHHHHHHHHTCCTTS------CC-EE-
1274 T ss_pred CCC---c--------------------------------hhhcCCCCHHHHHHHHHHHHHHhCCCccc------Cc-cc-
1275 Confidence 010 1 12334455677889999999999998621 11 11
1276
1277
1278 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAAQ--PFLLRNGANEGFHEAVGEIMSLSA 412 (805)
1279 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaaq--pfllrnganegfheavgeimslsa 412 (805)
1280 ..|||.+|+++.+|+||.||.+++ ++|+.+.|||+||++|.+.+..+ +..++.+++.+|||+++..|.+..
1281 T Consensus 232 -----~~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~ 306 (503)
1282 T 5GIV_F 232 -----LTHHPFMTRLGGHDVRITTRVKEQDPTDALYSTLHEAGHALYEQGVDAAFLGTPLGGGVSAGVHESQSRLWENLV 306 (503)
1283 T ss_dssp -----ECSSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHHHSCGGGTTSTTSSCSCHHHHHHHHHCCCCCC
1284 T ss_pred -----cCCCccccCCCCCcEEEEeecCCCChHHHHHHHHHHHHHHHHHcCCCHHHcCCCCCCccchHHHHHHHHHHHHhh
1285 Confidence 599999999988999999999999 69999999999999999988764 345578899999999999999999
1286
1287
1288 Q sp|Q9BYF1|ACE2 413 AT---------PKHLKSIGLLSPDF-QEDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWW 478 (805)
1289 Q Consensus 413 at---------pkhlksigllspdf-qednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkww 478 (805)
1290 .+ |++++.+|.+-.+. .++-...+| .+++.++.-+-.+|+.++..+|+|-+|.|+++.+++.+.||
1291 T Consensus 307 ~~~~~f~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~g~~~~~~l~~~w~ 386 (503)
1292 T 5GIV_F 307 GRSRAFWAAYFGDWRDTFPEQLAGVTEEEMYRAVNTVSRSLIRTDADELTYNLHVITRFELEREMLAGKLAVRDLADAWH 386 (503)
1293 T ss_dssp TTSHHHHHHHHHHHHHHSHHHHTTCCHHHHHHHTTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHTTSSCGGGHHHHHH
1294 T ss_pred cCCHHHHHHHHHHHHHHCcHHhCCCCHHHHHHHHHhhCHHHhHHHhhhhhhcHHHHHHHHHHHHHhcCCCCHHHHHHHHH
1295 Confidence 99 99999988542222 222333444 45677777778888899999999999999999999999999
1296
1297
1298 Q sp|Q9BYF1|ACE2 479 EMKREIVGVVEPVPHDETYCDPASLFHVSNDY---SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN--STEAGQK 553 (805)
1299 Q Consensus 479 emkreivgvvepvphdetycdpaslfhvsndy---sfiryytrtlyqfqfqealcqaakhegplhkcdisn--steagqk 553 (805)
1300 ++.++..|+..|. +...|+ ...|++.++ .|++|....++++|+.+++|+... .+|+| +.+ ..++|..
1301 T Consensus 387 ~~~~~y~G~~~~~--~~~~~~--~~~h~~~~~~~~y~~~Y~~g~i~a~ql~~~~~~~~~---~~~~~-~~~~~~~~~~~~ 458 (503)
1302 T 5GIV_F 387 AAYEQNLGLRAPS--DVDGAL--QDVHWYFGPIGGSFQGYTIGNVLSAQFYAAAEAANP---GLEAD-FARKDFSRLHGW 458 (503)
1303 T ss_dssp HHHHHHHSCCCSS--STTTTT--SCSGGGSSCSSSSSHHHHHHHHHHHHHHHHHHHHST---THHHH-HHTTCCHHHHHH
1304 T ss_pred HHHHHHhCCCCCC--CCCCCc--ccccccccCcccCCHHHHHHHHHHHHHHHHHHHhCC---ChHHH-hhcCChHHHHHH
1305 Confidence 9999999987553 334454 467888765 479999999999999999998764 49999 863 4688999
1306
1307
1308 Q sp|Q9BYF1|ACE2 554 LF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1309 Q Consensus 554 lf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1310 |- ++++.|.+.||.-.++.+.|. .++..++++||+|+++||-+
1311 T Consensus 459 l~~~il~~G~~~~~~ell~~~~g~-~ls~~~~l~y~~~~~~~~~~ 502 (503)
1312 T 5GIV_F 459 LRENVYRHGRRWTPGELIERATGQ-ALTAGPYLKYLRGKYGELYG 502 (503)
1313 T ss_dssp HCCCCCTTTTSSCHHHHHHHHHSS-SCCSHHHHHHHHHHHHHHHC
1314 T ss_pred HHHchHhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1315 Confidence 94 999999999999999999996 89999999999999999864
1316
1317
1318 No 15
1319 >3HQ2_B Bacillus subtilis M32 carboxypeptidase (E.C.3.4.24.-); Hydrolase, Metal-binding, Metalloprotease, Protease; HET: PO4; 2.9A {Bacillus subtilis}
1320 Probab=100.00 E-value=1.1e-47 Score=361.19 Aligned_cols=473 Identities=16% Similarity=0.152 Sum_probs=365.7 Template_Neff=10.100
1321
1322 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
1323 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
1324 ++-|++||.+++.++.++.+.+++++|+|.||+|+++.+........ |+.. -.+.+++-.++-+|+.++
1325 T Consensus 3 ~~~a~~~L~~~~~~~~~~~~~~~~~~Wd~~T~~p~~~~~~~~~~~~~----------l~~~-~~~~~~~~~~~r~l~~l~ 71 (501)
1326 T 3HQ2_B 3 IHTYEKEFFDLLKRISHYSEAVALMHWDSRTGAPKNGSEDRAESIGQ----------LSTD-IFNIQTSDRMKELIDVLY 71 (501)
1327 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTCCGGGHHHHHHHHHH----------HHHH-HHHHHHCHHHHHHHHHHH
1328 T ss_pred cchHHHHHHHHHHHHHhHHHHHHHHHHHHHhCCCCCChHHHHHHHHH----------HHHH-HHHHhcCHHHHHHHHHHH
1329 Confidence 45689999999999999999999999999999999887654433322 2222 234667788899999998
1330
1331
1332 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLRPL 179 (805)
1333 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlrpl 179 (805)
1334 ..|. .|+++.. ..++.|..+|+.++ |- .|.+-+.++++ .++|.++|+.||.. + +.++|+
1335 T Consensus 72 ~~~~-~l~~~~~----~~~~~~~~~~~~~~-~~----------~~~~~~~~~~~--~~~r~~~w~~~~~~-~~~~~~~~~ 132 (501)
1336 T 3HQ2_B 72 ERFD-DLSEDTK----KAVELAKKEYEENK-KI----------PEAEYKEYVIL--CSKAETAWEEAKGK-SDFSLFSPY 132 (501)
1337 T ss_dssp HTGG-GSCHHHH----HHHHHHHHHHHHHH-TS----------CHHHHHHHHHH--HHHHHHHHHHHHHH-TCHHHHHHH
1338 T ss_pred Hccc-CCCHHHH----HHHHHHHHHHHHcc-CC----------CHHHHHHHHHH--HHHHHHHHHHHHhc-CCHHHhHHH
1339 Confidence 8775 4665542 25788888898764 32 24444455544 45999999999986 6 789999
1340
1341
1342 Q sp|Q9BYF1|ACE2 180 YEEYVVLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISP 258 (805)
1343 Q Consensus 180 yeeyvvlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyisp 258 (805)
1344 +.++|-+++++|+.+.|++ ..|+|...|+- +.-.++++..|++|+|.|..+|+++|.|...
1345 T Consensus 133 l~~lv~l~~~~A~~~Gy~~~~~~~~~~~~~~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~~~-------- 194 (501)
1346 T 3HQ2_B 133 LEQLIEFNKRFITYWGYQEHPYDALLDLFEP----------GVTVKVLDQLFAELKEAIIPLVKQVTASGNK-------- 194 (501)
1347 T ss_dssp HHHHHHHHHHHHHHHCCSSCTTHHHHTTTST----------TCCHHHHHHHHHHHHHHHHHHHHHHHSCSCC--------
1348 T ss_pred HHHHHHHHHHHHHHccCCCChHHHHHHhhCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHHcCCC--------
1349 Confidence 9999999999999999995 49999887762 2335789999999999999999999986310
1350
1351
1352 Q sp|Q9BYF1|ACE2 259 IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGN 338 (805)
1353 Q Consensus 259 igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgn 338 (805)
1354 | | +.+..+.+...++++.++.+|.+.|++.. .|
1355 T Consensus 195 ----p-----------~-------------------~~~~~~~~~~~~~~~~~~~~~~~~G~~~~-~~------------ 227 (501)
1356 T 3HQ2_B 195 ----P-----------D-------------------TSFITKAFPKEKQKELSLYFLQELGYDFD-GG------------ 227 (501)
1357 T ss_dssp ----C-----------C-------------------CTTTTSCCCHHHHHHHHHHHHHHHTCCGG-GC------------
1358 T ss_pred ----C-----------C-------------------cchhcCcCCHHHHHHHHHHHHHHhCCCCC-CC------------
1359 Confidence 1 0 11233445556678889999999998752 11
1360
1361
1362 Q sp|Q9BYF1|ACE2 339 VQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAYA-AQPF-LLRNGANEGFHEAVGEIMSLS-AA 413 (805)
1363 Q Consensus 339 vqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmaya-aqpf-llrnganegfheavgeimsls-aa 413 (805)
1364 .....|||.+|+++.+|+||.+|.. ..++|+.+.|||+||++|.+.+. .+|+ .++.+++.+|||+++..|.+. +.
1365 T Consensus 228 r~~k~~~~~~~~~~~~d~ri~~~~~~~~~~~~~~tl~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~~~ 307 (501)
1366 T 3HQ2_B 228 RLDETVHPFATTLNRGDVRVTTRYDEKDFRTAIFGTIHECGHAIYEQNIDEALSGTNLSDGASMGIHESQSLFYENFIGR 307 (501)
1367 T ss_dssp CEEECSSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHTTSCGGGTTSTTCSCSCHHHHHHHHHHHCCCCCT
1368 T ss_pred CCCCCCCceeecCCCCceEEEEecChhhHHHHHHHHHHHHHHHHHHcCCCHHHCCCCccccccchhHHHHHHHHHHHhcC
1369 Confidence 1236899999999889999998877 56788999999999999999887 4887 789999999999999999988 66
1370
1371
1372 Q sp|Q9BYF1|ACE2 414 TPKHLKSIGL-LSPDFQE--------DNETEINF----LLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEM 480 (805)
1373 Q Consensus 414 tpkhlksigl-lspdfqe--------dneteinf----llkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwem 480 (805)
1374 .+.+++.+.. ++..|.+ +-...+|. +.++++..+..+++......|+|-+|.|+++.+++.+.||++
1375 T Consensus 308 ~~~~l~~~~~~~~~~~~~~l~~~~~~~l~~~l~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~~~~~~~~l~~~w~~~ 387 (501)
1376 T 3HQ2_B 308 NKHFWTPYYKKIQEASPVQFKDISLDDFVRAINESKPSFIRVEADELTYPLHIIIRYEIEKAIFSNEVSVEDLPSLWNQK 387 (501)
1377 T ss_dssp SGGGHHHHHHHHHHHSHHHHTTCCHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHTTTCCCGGGHHHHHHHH
1378 T ss_pred CHHHHHHHHHHHHHHCCccccCCCHHHHHHHHHhcCCCcchhHhHhhhHhHHHHHHHHHHHHHHcCCCCHhhHHHHHHHH
1379 Confidence 6666654422 2211111 11222332 333444445556666666799999999999889999999999
1380
1381
1382 Q sp|Q9BYF1|ACE2 481 KREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDI-SNSTEAGQKL-FN 556 (805)
1383 Q Consensus 481 kreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdi-snsteagqkl-fn 556 (805)
1384 ..+..|+..|. + ..++.+..|++.+| .+++|....++++|+.+++|+... .+|.|+. .+..++|++| -+
1385 T Consensus 388 ~~~y~g~~~~~--~--~~~~~~~~H~~~~~~~yy~~Y~~~~i~a~ql~~~~~~~~~---~~~~~~~~~~~~~~~~~l~~~ 460 (501)
1386 T 3HQ2_B 388 YQDYLGITPQT--D--AEGILQDVHWAGGDFGYFPSYALGYMYAAQLKQKMLEDLP---EFDALLERGEFHPIKQWLTEK 460 (501)
1387 T ss_dssp HHHHHSCCCCS--T--TTTGGGCSTTTTTCTTCTHHHHHHHHHHHHHHHHHHHHCT---THHHHHHTTCCHHHHHHHHHH
1388 T ss_pred HHHHhCCCCCC--C--CCcchhccccccccccCchHHHHHHHHHHHHHHHHHHhCc---cHHHHHHcCCchHHHHHHHHc
1389 Confidence 99999986553 2 26778889998764 488999999999999999998765 4899987 4566999999 49
1390
1391
1392 Q sp|Q9BYF1|ACE2 557 MLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1393 Q Consensus 557 mlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1394 +|..|.+.||.-.++.+.|. .+++++++.||+|+++|+.+
1395 T Consensus 461 ~l~~G~s~~~~e~l~~~~G~-~l~~~~~l~~~~~~~~~~~~ 500 (501)
1396 T 3HQ2_B 461 VHIHGKRKKPLDIIKDATGE-ELNVRYLIDYLSNKYSNLYL 500 (501)
1397 T ss_dssp TGGGTTSSCHHHHHHHHHSS-CCCTHHHHHHHHHHHHHTTC
1398 T ss_pred ccccccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1399 Confidence 99999999999999999998 89999999999999999864
1400
1401
1402 No 16
1403 >1K9X_B m32 carboxypeptidase; HEXXH motif, M32 family, metallopeptidase; 2.3A {Pyrococcus furiosus} SCOP: d.92.1.5
1404 Probab=100.00 E-value=1.1e-46 Score=357.76 Aligned_cols=470 Identities=16% Similarity=0.193 Sum_probs=361.6 Template_Neff=9.800
1405
1406 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 99 (805)
1407 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqa 99 (805)
1408 ..|+++.++|++++++...+.+++++++|+++||+++.+.+...++...++.++. +.+.+-.++-+|..
1409 T Consensus 4 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~wd~~t~~~~~~~~~~~~~~~~l~~~~~-----------~~~~~~~~~~~l~~ 72 (499)
1410 T 1K9X_B 4 VFQNETIKQILAKYRRIWAIGHAQSVLGWDLEVNMPKEGILERSVAQGELSVLSH-----------ELLLHPEFVNLVEK 72 (499)
1411 T ss_dssp CCCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHHHH-----------HHHTCHHHHHHHHH
1412 T ss_pred hhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCChhHHHHHHHHHHHHHHHHH-----------HHhhCHHHHHHHHH
1413 Confidence 3578899999999999999999999999999999999998887776666655544 35567778888888
1414
1415
1416 Q sp|Q9BYF1|ACE2 100 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLR 177 (805)
1417 Q Consensus 100 lqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlr 177 (805)
1418 +++. +.+++. ...+++.|..+|..+. .+.|.+.++++++. ++|.++|+.||.. + +.++
1419 T Consensus 73 ~~~~--~~l~~~----~~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~--~~~~~~w~~~~~~-~~~~~~~ 132 (499)
1420 T 1K9X_B 73 AKGL--ENLNEY----ERGIVRVLDRSIRIAR-----------AFPPEFIREVSETT--SLATKAWEEAKAK-DDFSKFE 132 (499)
1421 T ss_dssp HHHC--SSCCHH----HHHHHHHHHHHHHHHT-----------SSCHHHHHHHHHHH--HHHHHHHHHHHHT-TCGGGTH
1422 T ss_pred Hhcc--CCCCHH----HHHHHHHHHHHHHHHh-----------cCCHHHHHHHHHHH--HHHHHHHHHHHHc-CChHHhH
1423 Confidence 7765 344432 2346788888888764 46688999998875 6899999999984 7 8999
1424
1425
1426 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1427 Q Consensus 178 plyeeyvvlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1428 |+++++|-++++.|+.+.|++ +.|||...|+- +...++++..|++|+|+|..||++++.+. .
1429 T Consensus 133 ~~l~~lv~l~~~~A~~~G~~~s~~d~~~~~~~~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~--~----- 195 (499)
1430 T 1K9X_B 133 PWLDKIISLAKRAAEYLGYEEEPYDALLDLYEE----------GLRTRDVEKMFEVLEKKLKPLLDKILEEG--K----- 195 (499)
1431 T ss_dssp HHHHHHHHHHHHHHHHHCCSSCHHHHHHHHHST----------TCCHHHHHHHHHHCCCCCHHHHHHHHHHC--S-----
1432 T ss_pred HHHHHHHHHHHHHHHHcCCCCCHHHHHHHHhcC----------CCCHHHHHHHHHHHHHHHHHHHHHHHhcC--C-----
1433 Confidence 999999999999999999995 99999776653 34568999999999999999999999852 0
1434
1435
1436 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1437 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1438 .|+ +.|+. .+-++..++++.+++||.++|++.++.|..
1439 T Consensus 196 -----~~~-----------------~~p~~------------~~~~~~~~~~~~~~~~~~~lG~~~~~~~r~-------- 233 (499)
1440 T 1K9X_B 196 -----VPR-----------------EHPLE------------KEKYEREWMERVNLWILQKFGFPLGTRARL-------- 233 (499)
1441 T ss_dssp -----SCS-----------------CCGGG------------TCBCCHHHHHHHHHHHHHHHTCCBTTTEEE--------
1442 T ss_pred -----CCC-----------------CCccc------------cccCCHHHHHHHHHHHHHHhCCCcccCCcc--------
1443 Confidence 121 11221 122233457788999999999998853321
1444
1445
1446 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAA-QPFL-LRNGANEGFHEAVGEIMSLSA 412 (805)
1447 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaa-qpfl-lrnganegfheavgeimslsa 412 (805)
1448 .-.|||.+|+++.+|+||.+|...+ ++|+.+.||||||+.|.+.+.. +|.+ ++.+++.+|||+++..|....
1449 T Consensus 234 ----dk~~~~~~~~~~~~d~rI~~~~~~~~~~~~~~tl~HE~GHa~y~~~~~~~~~~~~~~~~~~~~~~E~~S~~~E~~~ 309 (499)
1450 T 1K9X_B 234 ----DVSAHPFTTEFGIRDVRITTRYEGYDFRRTILSTVHEFGHALYELQQDERFMFTPIAGGVSLGIHESQSRFWENII 309 (499)
1451 T ss_dssp ----EECSSCCEEEEETTEEEEEECCCSBCTHHHHHHHHHHHHHHHHHHTSCGGGTTSTTSSCSCHHHHHHHHHCCCCCC
1452 T ss_pred ----ccCCCCeeecCCcccEEEEeeecCccHHHHHHHHHHHHHHHHHHccCCccccCCcccccccchhHHHHHHHHHHHh
1453 Confidence 1589999999998999999999886 7899999999999999998875 5543 578899999999999998655
1454
1455
1456 Q sp|Q9BYF1|ACE2 413 ATP----KHLKSIGLLSPDFQ-------EDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKW 477 (805)
1457 Q Consensus 413 atp----khlksigllspdfq-------ednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkw 477 (805)
1458 ..+ +++.. .++..+. ++-...++ .+++.++..+..++...+.-.|+|.+|.|+++.+++.+.|
1459 T Consensus 310 ~~~~~~~~~l~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~~~~~~~~l~~~w 387 (499)
1460 T 1K9X_B 310 GRSKEFVELIYP--VLKENLPFMSNYTPEDVYLYFNIVRPDFIRTEADVVTYNFHILLRFKLERLMVSEEIKAKDLPEMW 387 (499)
1461 T ss_dssp TTSHHHHHHHHH--HHHHHCGGGGGCCHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHHSCCCGGGHHHHH
1462 T ss_pred cCCHHHHHHHHH--HHHHHCCCCCCCCHHHHHHHHhccCccccccccchhhHhHHHHHHHHHHHHHhcCCCCHHHhhHHH
1463 Confidence 433 33321 1222121 11112222 1222222233333334445678999999999999999999
1464
1465
1466 Q sp|Q9BYF1|ACE2 478 WEMKREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDI-SNSTEAGQKL 554 (805)
1467 Q Consensus 478 wemkreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdi-snsteagqkl 554 (805)
1468 |++..+..|+..|. +. .+.....|++.++ .|++|....++++|+.+++|+.. |+++.|.. ....++|++|
1469 T Consensus 388 ~~~~~~y~G~~~~~--~~--~~~~~~~H~~~~~~~yy~~Y~~~~i~a~ql~~~~~~~~---~~~~~~~~~~~~~~~g~~l 460 (499)
1470 T 1K9X_B 388 NDEMERLLGIRPRK--YS--EGILQDIHWAHGSIGYFPTYTIGTLLSAQLYYHIKKDI---PDFEEKVAKAEFDPIKAWL 460 (499)
1471 T ss_dssp HHHHHHHHSCCCSS--GG--GTTTSCSHHHHTCCSCTHHHHHHHHHHHHHHHHHTTTC---TTHHHHHHHTCCHHHHHHH
1472 T ss_pred HHHHHHHhCCCCCC--CC--CcchhhccccccccccchHHHHHHHHHHHHHHHHHHHC---CcHHHHHHcCCcHHHHHHH
1473 Confidence 99999999987543 22 4667888988766 67899999999999999999875 36777744 3447899999
1474
1475
1476 Q sp|Q9BYF1|ACE2 555 F-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFT 593 (805)
1477 Q Consensus 555 f-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplft 593 (805)
1478 . ++++.|.+.||.-.++.+.|. .++..|+++||+|++.
1479 T Consensus 461 ~~~~l~~G~~~~~~e~l~~~~G~-~l~~~~ll~~~~~~~~ 499 (499)
1480 T 1K9X_B 461 REKIHRWGSIYPPKELLKKAIGE-DMDAEYFVRWVKEKYL 499 (499)
1481 T ss_dssp HHHTGGGTTSSCHHHHHHHHHSS-CCCTHHHHHHHHHHHC
1482 T ss_pred HHcchhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHhC
1483 Confidence 5 999999999999999999999 7999999999999873
1484
1485
1486 No 17
1487 >1KA2_A M32 carboxypeptidase; HEXXH motif, M32 family, metallopeptidase; 2.2A {Pyrococcus furiosus} SCOP: d.92.1.5
1488 Probab=100.00 E-value=1.1e-46 Score=357.76 Aligned_cols=470 Identities=16% Similarity=0.193 Sum_probs=361.6 Template_Neff=9.800
1489
1490 Q sp|Q9BYF1|ACE2 20 TIEEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQA 99 (805)
1491 Q Consensus 20 tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqa 99 (805)
1492 ..|+++.++|++++++...+.+++++++|+++||+++.+.+...++...++.++. +.+.+-.++-+|..
1493 T Consensus 4 ~~~~~~~~~l~~~~~~~~~~~~~~~~~~wd~~t~~~~~~~~~~~~~~~~l~~~~~-----------~~~~~~~~~~~l~~ 72 (499)
1494 T 1KA2_A 4 VFQNETIKQILAKYRRIWAIGHAQSVLGWDLEVNMPKEGILERSVAQGELSVLSH-----------ELLLHPEFVNLVEK 72 (499)
1495 T ss_dssp CSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHHHH-----------HHHTCHHHHHHHHH
1496 T ss_pred hhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCChhHHHHHHHHHHHHHHHHH-----------HHhhCHHHHHHHHH
1497 Confidence 3578899999999999999999999999999999999998887776666655544 35567778888888
1498
1499
1500 Q sp|Q9BYF1|ACE2 100 LQQNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLR 177 (805)
1501 Q Consensus 100 lqqngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlr 177 (805)
1502 +++. +.+++. ...+++.|..+|..+. .+.|.+.++++++. ++|.++|+.||.. + +.++
1503 T Consensus 73 ~~~~--~~l~~~----~~~~~~~~~~~~~~~~-----------~l~~~l~~~~~~~~--~~~~~~w~~~~~~-~~~~~~~ 132 (499)
1504 T 1KA2_A 73 AKGL--ENLNEY----ERGIVRVLDRSIRIAR-----------AFPPEFIREVSETT--SLATKAWEEAKAK-DDFSKFE 132 (499)
1505 T ss_dssp HHTC--SSCCHH----HHHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHH--HHHHHHHHHHHHT-TCGGGTH
1506 T ss_pred Hhcc--CCCCHH----HHHHHHHHHHHHHHHh-----------cCCHHHHHHHHHHH--HHHHHHHHHHHHc-CChHHhH
1507 Confidence 7765 344432 2346788888888764 46688999998875 6899999999984 7 8999
1508
1509
1510 Q sp|Q9BYF1|ACE2 178 PLYEEYVVLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYI 256 (805)
1511 Q Consensus 178 plyeeyvvlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyi 256 (805)
1512 |+++++|-++++.|+.+.|++ +.|||...|+- +...++++..|++|+|+|..||++++.+. .
1513 T Consensus 133 ~~l~~lv~l~~~~A~~~G~~~s~~d~~~~~~~~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~--~----- 195 (499)
1514 T 1KA2_A 133 PWLDKIISLAKRAAEYLGYEEEPYDALLDLYEE----------GLRTRDVEKMFEVLEKKLKPLLDKILEEG--K----- 195 (499)
1515 T ss_dssp HHHHHHHHHHHHHHHHHCCSSCHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHHTT--C-----
1516 T ss_pred HHHHHHHHHHHHHHHHcCCCCCHHHHHHHHhcC----------CCCHHHHHHHHHHHHHHHHHHHHHHHhcC--C-----
1517 Confidence 999999999999999999995 99999776653 34568999999999999999999999852 0
1518
1519
1520 Q sp|Q9BYF1|ACE2 257 SPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDP 336 (805)
1521 Q Consensus 257 spigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdp 336 (805)
1522 .|+ +.|+. .+-++..++++.+++||.++|++.++.|..
1523 T Consensus 196 -----~~~-----------------~~p~~------------~~~~~~~~~~~~~~~~~~~lG~~~~~~~r~-------- 233 (499)
1524 T 1KA2_A 196 -----VPR-----------------EHPLE------------KEKYEREWMERVNLWILQKFGFPLGTRARL-------- 233 (499)
1525 T ss_dssp -----SCS-----------------CCGGG------------TCBCCHHHHHHHHHHHHHHHTCCBTTTEEE--------
1526 T ss_pred -----CCC-----------------CCccc------------cccCCHHHHHHHHHHHHHHhCCCcccCCcc--------
1527 Confidence 121 11221 122233457788999999999998853321
1528
1529
1530 Q sp|Q9BYF1|ACE2 337 GNVQKAVCHPTAWDLGKGDFRILMCTKVT--MDDFLTAHHEMGHIQYDMAYAA-QPFL-LRNGANEGFHEAVGEIMSLSA 412 (805)
1531 Q Consensus 337 gnvqkavchptawdlgkgdfrilmctkvt--mddfltahhemghiqydmayaa-qpfl-lrnganegfheavgeimslsa 412 (805)
1532 .-.|||.+|+++.+|+||.+|...+ ++|+.+.||||||+.|.+.+.. +|.+ ++.+++.+|||+++..|....
1533 T Consensus 234 ----dk~~~~~~~~~~~~d~rI~~~~~~~~~~~~~~tl~HE~GHa~y~~~~~~~~~~~~~~~~~~~~~~E~~S~~~E~~~ 309 (499)
1534 T 1KA2_A 234 ----DVSAHPFTTEFGIRDVRITTRYEGYDFRRTILSTVHEFGHALYELQQDERFMFTPIAGGVSLGIHESQSRFWENII 309 (499)
1535 T ss_dssp ----EECSSCCEEEEETTEEEEEECCCSBCTHHHHHHHHHHHHHHHHHHTCCGGGTTSTTSSCCCHHHHHHHHHCCCCCC
1536 T ss_pred ----ccCCCCeeecCCcccEEEEeeecCccHHHHHHHHHHHHHHHHHHccCCccccCCcccccccchhHHHHHHHHHHHh
1537 Confidence 1589999999998999999999886 7899999999999999998875 5543 578899999999999998655
1538
1539
1540 Q sp|Q9BYF1|ACE2 413 ATP----KHLKSIGLLSPDFQ-------EDNETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKW 477 (805)
1541 Q Consensus 413 atp----khlksigllspdfq-------ednetein----fllkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkw 477 (805)
1542 ..+ +++.. .++..+. ++-...++ .+++.++..+..++...+.-.|+|.+|.|+++.+++.+.|
1543 T Consensus 310 ~~~~~~~~~l~~--~~~~~~~~~~~~~~~~l~~~l~~~~~~l~r~~~~~l~~~~~~~~~~~~e~~l~~~~~~~~~l~~~w 387 (499)
1544 T 1KA2_A 310 GRSKEFVELIYP--VLKENLPFMSNYTPEDVYLYFNIVRPDFIRTEADVVTYNFHILLRFKLERLMVSEEIKAKDLPEMW 387 (499)
1545 T ss_dssp TTSHHHHHHHHH--HHHHHCGGGGGCCHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHHSCCCGGGHHHHH
1546 T ss_pred cCCHHHHHHHHH--HHHHHCCCCCCCCHHHHHHHHhccCccccccccchhhHhHHHHHHHHHHHHHhcCCCCHHHhhHHH
1547 Confidence 433 33321 1222121 11112222 1222222233333334445678999999999999999999
1548
1549
1550 Q sp|Q9BYF1|ACE2 478 WEMKREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDI-SNSTEAGQKL 554 (805)
1551 Q Consensus 478 wemkreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdi-snsteagqkl 554 (805)
1552 |++..+..|+..|. +. .+.....|++.++ .|++|....++++|+.+++|+.. |+++.|.. ....++|++|
1553 T Consensus 388 ~~~~~~y~G~~~~~--~~--~~~~~~~H~~~~~~~yy~~Y~~~~i~a~ql~~~~~~~~---~~~~~~~~~~~~~~~g~~l 460 (499)
1554 T 1KA2_A 388 NDEMERLLGIRPRK--YS--EGILQDIHWAHGSIGYFPTYTIGTLLSAQLYYHIKKDI---PDFEEKVAKAEFDPIKAWL 460 (499)
1555 T ss_dssp HHHHHHHHSCCCSS--GG--GTTTSCSHHHHTCTTCTHHHHHHHHHHHHHHHHHHHHC---TTHHHHHHHTCCHHHHHHH
1556 T ss_pred HHHHHHHhCCCCCC--CC--CcchhhccccccccccchHHHHHHHHHHHHHHHHHHHC---CcHHHHHHcCCcHHHHHHH
1557 Confidence 99999999987543 22 4667888988766 67899999999999999999875 36777744 3447899999
1558
1559
1560 Q sp|Q9BYF1|ACE2 555 F-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFT 593 (805)
1561 Q Consensus 555 f-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplft 593 (805)
1562 . ++++.|.+.||.-.++.+.|. .++..|+++||+|++.
1563 T Consensus 461 ~~~~l~~G~~~~~~e~l~~~~G~-~l~~~~ll~~~~~~~~ 499 (499)
1564 T 1KA2_A 461 REKIHRWGSIYPPKELLKKAIGE-DMDAEYFVRWVKEKYL 499 (499)
1565 T ss_dssp HHHTGGGTTSSCHHHHHHHHHSS-CCCTHHHHHHHHHHHC
1566 T ss_pred HHcchhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHhC
1567 Confidence 5 999999999999999999999 7999999999999873
1568
1569
1570 No 18
1571 >5E3X_A Thermostable carboxypeptidase 1; Carboxypeptidase, Fervidobacterium, FisCP, HYDROLASE; 2.197A {Fervidobacterium islandicum}
1572 Probab=100.00 E-value=2.4e-46 Score=356.74 Aligned_cols=456 Identities=17% Similarity=0.229 Sum_probs=345.9 Template_Neff=9.600
1573
1574 Q sp|Q9BYF1|ACE2 27 TFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQQNGSS 106 (805)
1575 Q Consensus 27 tfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngss 106 (805)
1576 .||+.++.+++.+.++.++++|+|.||+++++.+.+..+...++.+ ..+.+++-+++-||+.++..
1577 T Consensus 2 ~~l~~~~~~~~~~~~~~~~~~Wd~~t~~~~~~~~~r~~~~~~l~~~-----------~~~~~~~~~~~~~l~~~~~~--- 67 (489)
1578 T 5E3X_A 2 EELKSYYKRVAKYYSAAALLYWDMQTYMPKDAGPYRAEVLSEIGTY-----------AFKQITDDALGKLLETAQPQ--- 67 (489)
1579 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHH-----------HHHHHTSHHHHHHHHHCCCC---
1580 T ss_pred hHHHHHHHHHHHHHHHHHHHHHHHHhcCCCCchHHHHHHHHHHHHH-----------HHHHhcCHHHHHHHHHhCCC---
1581 Confidence 4889999999999999999999999999999998766665555543 33457788899999888752
1582
1583
1584 Q sp|Q9BYF1|ACE2 107 VLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG--KQLRPLYEEYV 184 (805)
1585 Q Consensus 107 vlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg--kqlrplyeeyv 184 (805)
1586 +.+...++..|..+|++++++ .|.+-++++++.+..+ ++|..||.. + +.++|.|+++|
1587 T Consensus 68 ------~~~~~~~~~~~~~~~~~~~~~-----------~~~l~~~~~~~~~~~~--~~W~~~r~~-~~~~~~~~~~~~~v 127 (489)
1588 T 5E3X_A 68 ------SEIDEKLVYVGKKEYYKYKKV-----------PPELFQEIMITSTMLE--QKWEIAKPR-GDFEEVRPLLEKIV 127 (489)
1589 T ss_dssp ------SHHHHHHHHHHHHHHHHHHTS-----------CHHHHHHHHHHHHHHH--HHHHHHGGG-TCSTTTHHHHHHHH
1590 T ss_pred ------CHHHHHHHHHHHHHHHhccCC-----------CHHHHHHHHHhhhHHH--HHHHHHHhc-CCHHHHHHHHHHHH
1591 Confidence 234667788999999998763 4667788888888776 999999996 8 89999999999
1592
1593
1594 Q sp|Q9BYF1|ACE2 185 VLKNEMARANHYED-YGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLP 263 (805)
1595 Q Consensus 185 vlknemaranhyed-ygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispigclp 263 (805)
1596 -+.|++|+.+.|++ .+++|...|+-. + ..++++..|++| +.+||..|.+.|+.. |
1597 T Consensus 128 ~l~~~~A~~~g~~~~~y~~~~~~y~~~----~------~~~~l~~~~~~l-------~~~v~~~l~~~~~~~-------~ 183 (489)
1598 T 5E3X_A 128 DLSRKYADILGYEGEPYNALLDLYEPG----M------KAEEVDQIFSKV-------RDFIVEVLEKIERLP-------K 183 (489)
1599 T ss_dssp HHHHHHHHTTCCSSCHHHHHHHHHSTT----C------CHHHHHHHHHHH-------HHHHHHHHHHHHHSC-------C
1600 T ss_pred HHHHHHHHHhCCCCChHHHHHHHhCCC----C------CHHHHHHHHHHH-------HHHHHHHHHHHhcCC-------C
1601 Confidence 99999999999987 568887766542 1 124455555554 556888887777431 3
1602
1603
1604 Q sp|Q9BYF1|ACE2 264 AHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAV 343 (805)
1605 Q Consensus 264 ahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkav 343 (805)
1606 +| +.++.|+.. + .++.+. +.++.+.|... ++|... ..
1607 T Consensus 184 ~~-------------~~~~~~~~~----~-----------~~~~~~--~~~~~~~g~d~------------~~~~~~-~~ 220 (489)
1608 T 5E3X_A 184 SE-------------DPFNREIGV----D-----------KQKEFS--NWLLHYLKYDF------------TKGRLD-VS 220 (489)
1609 T ss_dssp CC-------------CTTCSCCCH----H-----------HHHHHH--HHHHHHTTCCT------------TSCCEE-EC
1610 T ss_pred CC-------------CcccCCCCH----H-----------HHHHHH--HHHHHHcCCCC------------CCCCee-cc
1611 Confidence 32 223333321 1 122222 45667777665 122221 38
1612
1613
1614 Q sp|Q9BYF1|ACE2 344 CHPTAWDLGKGDFRILMCT--KVTMDDFLTAHHEMGHIQYDMAYAAQ--PFLLRNGANEGFHEAVGEIMSLSAAT----- 414 (805)
1615 Q Consensus 344 chptawdlgkgdfrilmct--kvtmddfltahhemghiqydmayaaq--pfllrnganegfheavgeimslsaat----- 414 (805)
1616 |||..++++.+|+||.+|. +++++|+.+.|||+||++|.+.+..+ ...++.+++.+|||+++..|.+....
1617 T Consensus 221 ~~~~~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~~~~~~~~~~~E~~s~~~E~~~~~~l~~~ 300 (489)
1618 T 5E3X_A 221 AHPFTNPIGLNDVRITTRYIVNDIRNSIYSTIHEFGHALYALSIPTEFYGLPIGSSASYGFDESQSRFWENVVGRSLAFW 300 (489)
1619 T ss_dssp SSCCEEEEETTEEEEEECCCTTCHHHHHHHHHHHHHHHHHHHHSCGGGTTSGGGSCSCHHHHHHHHHCCCCCCTTSHHHH
1620 T ss_pred CCCccCCCCCCceEEeeeccccchhHHHHHHHHHHHHHHHHcCCChHHcCCCCccccCcccchhHHHHHHHHhhcCHHHH
1621 Confidence 9999999988999999999 99999999999999999999988752 22236789999999999999887776
1622
1623
1624 Q sp|Q9BYF1|ACE2 415 ----PKHLKSIGLLSPDFQEDNETEINFLLKQALT-IVGT-------LPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKR 482 (805)
1625 Q Consensus 415 ----pkhlksigllspdfqedneteinfllkqalt-ivgt-------lpftymlekwrwmvfkgeipkdqwmkkwwemkr 482 (805)
1626 |+|++.+|++. +.. ..++...+.++.. ...+ ++...+...|+|.++.|+++.+++-+.||+...
1627 T Consensus 301 ~~~~~~~~~~l~~~~-~~~---~~~~~~~l~~~~~~~~~~~~d~l~~~~~~~~~~~~e~~~~~g~~~~~~l~~~w~~~~~ 376 (489)
1628 T 5E3X_A 301 KGIYSKFIEIVPEMR-GYS---VEELWRAVNRVQRSFIRTEADEVTYNLHIIIRFEIERELINGELSVKDVPDKWNELYK 376 (489)
1629 T ss_dssp HHHHHHHHHHCGGGT-TSC---HHHHHHHTSCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHTTSSCGGGHHHHHHHHHH
1630 T ss_pred HHHHHHHHHHchhhc-CCC---HHHHHHHHHHHccccchhHhHHHHHHHHHHHHHHHHHHHHhCCCCHhhhhHHHHHHHH
1631 Confidence 77878887651 221 1122222222211 1121 244567799999999999999999999999999
1632
1633
1634 Q sp|Q9BYF1|ACE2 483 EIVGVVEPVPHDETYCDPASLFHVSN-DY-SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDIS-NS-TEAGQKLF-NM 557 (805)
1635 Q Consensus 483 eivgvvepvphdetycdpaslfhvsn-dy-sfiryytrtlyqfqfqealcqaakhegplhkcdis-ns-teagqklf-nm 557 (805)
1636 +..|+..|. + ..++....|+.. .| .+++|....++++|+.+++|+.. +++.| +. ++ .++|+.|- ++
1637 T Consensus 377 ~y~g~~~~~--~--~~~~~~~~h~~~~~~~y~~~Y~~~~i~a~ql~~~~~~~~----~~~~~-~~~~~~~~~g~~l~~~~ 447 (489)
1638 T 5E3X_A 377 KYLGLDVPN--N--TLGCMQDPHWFGGNFGYFPTYALGNLYAAQIFEKLKEEI----NFEEV-VSAGNFEIIKNFLKEKI 447 (489)
1639 T ss_dssp HHHCCCCCS--T--TTTTTSCSGGGGTCCSCTHHHHHHHHHHHHHHHHHHHHS----CHHHH-HHHTCTHHHHHHHHHHT
1640 T ss_pred HHhCCCCCC--C--CCCCCCCCcccccccchhHHHHHHHHHHHHHHHHHHHcC----CHHHH-HhcCCHHHHHHHHHHch
1641 Confidence 999975443 2 235667788875 67 89999999999999999999865 69999 54 55 57899998 59
1642
1643
1644 Q sp|Q9BYF1|ACE2 558 LRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKD 597 (805)
1645 Q Consensus 558 lrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkd 597 (805)
1646 +..|.+.||.-.++++.|. .+++++++.||+|++.|+..
1647 T Consensus 448 l~~G~~~~~~e~l~~~~G~-~ls~~~~l~~~~~~~~~~~~ 486 (489)
1648 T 5E3X_A 448 HSKGKMYEPSDLIKIVTGK-PLSYESFVRYIKDKYSKVYE 486 (489)
1649 T ss_dssp GGGTTSSCHHHHHHHHHSS-CCCSHHHHHHHHHHHHHHHT
1650 T ss_pred hhcCcCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHHhc
1651 Confidence 9999999999999999998 89999999999999999974
1652
1653
1654 No 19
1655 >3HOA_A Thermostable carboxypeptidase 1 (E.C.3.4.17.19); proline-rich loop, Carboxypeptidase, Hydrolase; 2.1A {Thermus thermophilus HB27}
1656 Probab=100.00 E-value=1.1e-45 Score=356.95 Aligned_cols=468 Identities=19% Similarity=0.228 Sum_probs=373.5 Template_Neff=9.300
1657
1658 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
1659 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
1660 ++++..||++++.+...+-+..++++|++.|++++.+.+..... .++|+.. -.+.+.+-.++-+|..++
1661 T Consensus 3 ~~~~~~~l~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~r~~~----------~~~l~~~-~~~~~~~~~~~~~l~~~~ 71 (509)
1662 T 3HOA_A 3 PEAAYQNLLEFQRETAYLASLGALAAWDQRTMIPKKGHEHRARQ----------MAALARL-LHQRMTDPRIGEWLEKVE 71 (509)
1663 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHH----------HHHHHHH-HHHHHTCHHHHHHHHHHT
1664 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCCCHHhHHHHHHH----------HHHHHHH-HHHhhcCHHHHHHHHHHc
1665 Confidence 56788999999999999999999999999999998876443322 2233332 234566777888888887
1666
1667
1668 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEV-GKQLRPLY 180 (805)
1669 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsev-gkqlrply 180 (805)
1670 .. ...+.+ ...+..++..|..+|...+ .++|.+.++|+++.++.+ ++|..||.+. +..++|.+
1671 T Consensus 72 ~~-~~~~~~--~~~~~~~~~~~~~~~~~~~-----------~~~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~~~l 135 (509)
1672 T 3HOA_A 72 GS-PLVQDP--LSDAAVNVREWRQAYERAR-----------AIPERLAVELAQAESEAE--SFWEEARPRDDWRGFLPYL 135 (509)
1673 T ss_dssp TS-GGGSST--TSHHHHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHTTTTCHHHHHHHH
1674 T ss_pred CC-CCCCCC--CHHHHHHHHHHHHHHHHHc-----------CCCHHHHHHHHHcccHHH--HHHHHhhhhCChhhhHHHH
1675 Confidence 65 333332 4556678899999998766 678899999999999999 8999999998 89999999
1676
1677
1678 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYE----------DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1679 Q Consensus 181 eeyvvlknemaranhye----------dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1680 +++|-++|+.|+.+.|. ++.|||...|+- |...++++..|++|+|+|..||+|||.+.
1681 T Consensus 136 ~~~v~l~~~~A~~~g~~~~~~~~~~~~~~~d~~l~~ye~----------~~~~~~l~~l~~~l~~~~~~l~~~~~~~~-- 203 (509)
1682 T 3HOA_A 136 KRVYALTKEKAEVLFALPPAPGDPPYGELYDALLDGYEP----------GMRARELLPLFAELKEGLKGLLDRILGSG-- 203 (509)
1683 T ss_dssp HHHHHHHHHHHHHHHTSCCCTTSCCCCSHHHHHHHHHST----------TCCHHHHHHHHHHHHHHHHHHHHHHHTCS--
1684 T ss_pred HHHHHHHHHHHHHhhcCCCCCCCCCCCCHHHHHHHccCC----------CCCHHHHHHHHHHHHHHHHHHHHHHHccC--
1685 Confidence 99999999999999997 999999988872 22358899999999999999999999964
1686
1687
1688 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWEN 330 (805)
1689 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwen 330 (805)
1690 |. | |+|++ .+.+...+.++-++++|.+.|+.. ++
1691 T Consensus 204 -~~----~----~~~~~-------------------------------~~~~~~~~~~~~~~~~~~~lG~~~------~~ 237 (509)
1692 T 3HOA_A 204 -KR----P----DTSIL-------------------------------HRPYPVEAQRRFALELLSACGYDL------EA 237 (509)
1693 T ss_dssp -CC----C----CGGGG-------------------------------GSCCCHHHHHHHHHHHHHHHTCCG------GG
1694 T ss_pred -CC----C----Cchhh-------------------------------cCCCCHHHHHHHHHHHHHHCCCCh------hh
1695 Confidence 21 1 44421 122233456788899999999886 12
1696
1697
1698 Q sp|Q9BYF1|ACE2 331 SMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAYAA----QPFLLRNGANEGFHEAV 404 (805)
1699 Q Consensus 331 smltdpgnvqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmayaa----qpfllrnganegfheav 404 (805)
1700 +. +. ..|||.+|+++.+|+||++|.. ..++++.+.|||+||..|.+.+.. +| ++.+++.+|||++
1701 T Consensus 238 ~~------~d-k~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~--~~~~~~~~~~E~~ 308 (509)
1702 T 3HOA_A 238 GR------LD-PTAHPFEIAIGPGDVRITTRYYEDFFNAGIFGTLHEMGHALYEQGLPKEHWGTP--RGDAVSLGVHESQ 308 (509)
1703 T ss_dssp EE------EE-ECSSCCEEEEETTEEEEEECCBTTBHHHHHHHHHHHHHHHHHHHHSCGGGTTSG--GGSCCCHHHHHHH
1704 T ss_pred CC------CC-CCCCcceeccCCCceEEEEeeccchhhHHHHHHHHHHHHHHHHhCCCHHHCCCC--CcCCCCchhHHHH
1705 Confidence 21 11 5799999999988999999998 899999999999999999998843 44 5678999999999
1706
1707
1708 Q sp|Q9BYF1|ACE2 405 GEIMS----LSAATPKHLKS-----IGLLSPDFQEDNETEINF----LLKQALTIVGTLPFTYMLEKWRW--MVFKGEIP 469 (805)
1709 Q Consensus 405 geims----lsaatpkhlks-----igllspdfqedneteinf----llkqaltivgtlpftymlekwrw--mvfkgeip 469 (805)
1710 +..|. .+..+++++.. +|++++...++-...+|. ++++++..+. .|+.+++ +|+| .++.|+++
1711 T Consensus 309 s~~~E~~~~~~~~~~~~l~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~r~~~~~~~-~~~~~~~-~~~~E~~l~~~~~~ 386 (509)
1712 T 3HOA_A 309 SRTWENLVGRSLGFWERFFPRAREVFASLGDVSLEDFHFAVNAVEPSLIRVEADEVT-YNLHILV-RLELELALFRGELS 386 (509)
1713 T ss_dssp HHCCCCCCTTSHHHHHHHHHHHHHHCGGGTTCCHHHHHHHTTCCCCCSCGGGCCTTT-HHHHHHH-HHHHHHHHHTTSCC
1714 T ss_pred HHHHHHHhcCCHHHHHHHHHHHHHHhhccCCCCHHHHHHHHHccChhHHHHHhHHhH-hhHHHHH-HHHHHHHHHcCCCC
1715 Confidence 99998 67778877765 676544324444566666 7888887765 8998888 9999 89999999
1716
1717
1718 Q sp|Q9BYF1|ACE2 470 KDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSND--YSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDIS-- 545 (805)
1719 Q Consensus 470 kdqwmkkwwemkreivgvvepvphdetycdpaslfhvsnd--ysfiryytrtlyqfqfqealcqaakhegplhkcdis-- 545 (805)
1720 .+++-+.||+..++..|+..|. +...| ....|.+.. +.|.+|....++++|+.+++|+.. |+++.| +.
1721 T Consensus 387 ~~~l~~~w~~~~~~y~G~~~~~--~~~~~--~~~~h~~~~~~~Y~~~Y~~g~i~a~ql~~~~~~~~---~~~~~~-~~~~ 458 (509)
1722 T 3HOA_A 387 PEDLPEAWAEKYRDHLGVAPKD--YKDGV--MQDVHWAGGLFGYFPTYTLGNLYAAQFFQKAEAEL---GPLEPR-FARG 458 (509)
1723 T ss_dssp GGGHHHHHHHHHHHHHSCCCSS--STTTT--TSCSTTTTTCCSCTHHHHHHHHHHHHHHHHHHHHH---CCHHHH-HHHT
1724 T ss_pred HhHHhHHHHHHHHHHhCCCCCC--CCCCc--cccCcccCCccchhHHHHHHHHHHHHHHHHHHHHH---CChhHH-hhcC
1725 Confidence 9999999999999999987553 33333 444566543 345688899999999999999876 489999 54
1726
1727
1728 Q sp|Q9BYF1|ACE2 546 NSTEAGQKLF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTW 594 (805)
1729 Q Consensus 546 nsteagqklf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftw 594 (805)
1730 +..++|..|- ++++.|.+.+|.-.++.+.|. .++..+++.||++.+.-
1731 T Consensus 459 ~~~~~g~~l~~~il~~G~s~~~~ell~~~~G~-~l~~~~~l~~~~~~~~~ 507 (509)
1732 T 3HOA_A 459 EFQPFLDWTRARIHAEGSRFRPRVLVERVTGE-APSARPFLAYLEKKYAA 507 (509)
1733 T ss_dssp CCHHHHHHHHHHTGGGTTSSCHHHHHHHHHSS-CCCSHHHHHHHHHHHHH
1734 T ss_pred CcHHHHHHHHHhHHhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHH
1735 Confidence 4579999997 899999999999999999998 89999999999987753
1736
1737
1738 No 20
1739 >3DWC_B Metallocarboxypeptidase (E.C.3.4.17.19); metallocarboxypeptidase, cowrin family of metallocarboxypeptidases; HET: GOL, SO4; 2.1A {Trypanosoma cruzi}
1740 Probab=100.00 E-value=2e-44 Score=343.88 Aligned_cols=459 Identities=16% Similarity=0.165 Sum_probs=360.6 Template_Neff=9.700
1741
1742 Q sp|Q9BYF1|ACE2 23 EQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQE-I------QNLTVKL 95 (805)
1743 Q Consensus 23 eqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqe-i------qnltvkl 95 (805)
1744 ..|..||..++.+.+.+-++.++++|++.||+++.+.+.+..+..+++.++.+..+-.+++.+-+ + .+-..+.
1745 T Consensus 3 ~~~~~~l~~~~~~~~~l~~~~~~~~Wd~~t~~~~~~~~~~~~~~~~ls~~~~~~~~~~~~~~~~~~~~~~~~~ld~~~~r 82 (505)
1746 T 3DWC_B 3 MKPYKELERVFTKLYRYGHMLLLADWDSHTMMPCKGSDARGAAMAELQLHMHDTITAPKIRALIEEAEKSVGDLEKLQRA 82 (505)
1747 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCCGGGHHHHHHHHHHHHHHHHHHHTSHHHHHHHHHHHHTGGGSCHHHHH
1748 T ss_pred chHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCCCccHHHHHHHHHHHHHHHHhhhhCHHHHHHHHHHHhhcCCCCHHHHH
1749 Confidence 35778999999999999999999999999999999999999999999999999777555544211 1 1345677
1750
1751
1752 Q sp|Q9BYF1|ACE2 96 QLQALQQN--GSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG 173 (805)
1753 Q Consensus 96 qlqalqqn--gssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg 173 (805)
1754 ||+.++.. ++..|+++.-++++.+.+.|+.+|++.+.||. .
1755 T Consensus 83 ~l~~l~~~~~~~~~lp~~~~~~~~~~~~~~~~~w~~~r~~~~-------------------------------------~ 125 (505)
1756 T 3DWC_B 83 NLREMRRAWELENLLPEEFVERKTVLTTKAHQVWKTCREKND-------------------------------------F 125 (505)
1757 T ss_dssp HHHHHHHHHHHHHSSCHHHHHHHHHHHHHHHHHHHHHHHHTC-------------------------------------H
1758 T ss_pred HHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHhhhcCC-------------------------------------h
1759 Confidence 78888887 88899999999999999999999999888731 1
1760
1761
1762 Q sp|Q9BYF1|ACE2 174 KQLRPLYEEYVVLKNEMARANHYE---DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1763 Q Consensus 174 kqlrplyeeyvvlknemaranhye---dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1764 +.++|.++++|-++++.|+.+.|+ +..|+|...|+ .|...++++..|++|+|+|..||++||.++..
1765 T Consensus 126 ~~~~~~~~~~v~l~~~~A~~~g~~~~~~~y~~~~~~y~----------~~~~~~~ld~l~~~i~~~~~~l~~~v~~~~~~ 195 (505)
1766 T 3DWC_B 126 AGFLPTLKELIALFREEGKLRAGNSGKHPYEALVDIYE----------PGMTLQRLDEIFGNVRSWLPELLKEVQEKQKA 195 (505)
1767 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHTTSCCCHHHHHHHHHS----------TTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
1768 T ss_pred hhhHHHHHHHHHHHHHHHHHHcCCCCCChHHHHHHHhC----------CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHh
1769 Confidence 578999999999999999999986 77778866555 34455889999999999999999999998762
1770
1771
1772 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWEN 330 (805)
1773 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwen 330 (805)
1774 |+ + +.+.+..||... ..++-++++|.++|... ++
1775 T Consensus 196 -~~---------------~-------~~~~~~~p~~~~-----------------~~~~~~~~~~~~lg~~~------~~ 229 (505)
1776 T 3DWC_B 196 -LG---------------E-------TVLEPKGPFPVS-----------------KQEALCRFFMDVWKFDF------DG 229 (505)
1777 T ss_dssp -HC---------------C-------CCCCCCSCCCHH-----------------HHHHHHHHHHHHTTCCT------TS
1778 T ss_pred -hC---------------C-------CCCCCCCCCCHH-----------------HHHHHHHHHHHHcCCCc------cC
1779 Confidence 21 1 112334555221 23455677888888774 22
1780
1781
1782 Q sp|Q9BYF1|ACE2 331 SMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAY-AA----QPFLLRNGANEGFHEA 403 (805)
1783 Q Consensus 331 smltdpgnvqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmay-aa----qpfllrnganegfhea 403 (805)
1784 +.+ | ..|||.+|+++ +|+||.+|.+ .+++|+.+.|||+||++|.+.+ .. ||+. .+++-+|||+
1785 T Consensus 230 ~~~-d------~~~~~f~~~~~-~d~ri~~~~~~~~~~~~~~~l~HE~GHa~y~~~~~~~~~~~~p~~--~~~~~~~~E~ 299 (505)
1786 T 3DWC_B 230 GRL-D------VSAHPFCGNSK-EDVRITTKYTETEFVTSLLGVIHETGHAKYEQNCGPKGFETQPVC--MARSLGVHEG 299 (505)
1787 T ss_dssp EEE-E------ECSSCCEEEET-TEEEEEECCBTTBSHHHHHHHHHHHHHHHHHHTCCCTTCTTSTTS--SCSCHHHHHH
1788 T ss_pred Cce-e------ecCCCccCCCC-CceEEEecCCchHHHHHHHHHHHHHHHHHHHhcCCCccccCCchh--hhcccchhHH
1789 Confidence 222 2 38999999985 8999999999 7799999999999999999988 43 7875 6899999999
1790
1791
1792 Q sp|Q9BYF1|ACE2 404 VGE----IMSLSAATPKHLKSIGLLSPDFQEDN-------ETEIN----FLLKQALTIVGTLPFTYMLEKWRWMVFKGEI 468 (805)
1793 Q Consensus 404 vge----imslsaatpkhlksigllspdfqedn-------etein----fllkqaltivgtlpftymlekwrwmvfkgei 468 (805)
1794 ++. ++..++.+|+||..+... .|.... ..-++ .++++++..+..++...+...|+|-+|.|++
1795 T Consensus 300 ~s~~~E~~~~~~~~~~~~l~~~~~~--~~~~~~~~~~~~l~~~l~~~~~~~~r~~~~~l~~~~~~~~~~~~e~~l~~g~~ 377 (505)
1796 T 3DWC_B 300 QSLFAEMQIGRSGAFMEFLAPRLVE--YFGDQPAFTSSNMKRVIQRVSPGLIRIDADELCYPLHVMLRYEIERDLMDGNI 377 (505)
1797 T ss_dssp HHHCCCCCCCTSHHHHHHHHHHHHH--HHCCCTTCSHHHHHHHHTCCCCCSCGGGCCTTTHHHHHHHHHHHHHHHHHTSS
1798 T ss_pred HHHHHHHHhhcCHHHHHHHHHHHHH--HHCCCCCCCHHHHHHHHhccCCcccHHHchhcchHHHHHHHHHHHHHHHcCCC
1799 Confidence 984 445677899999876322 222111 11122 3344444444444445566689999999999
1800
1801
1802 Q sp|Q9BYF1|ACE2 469 PKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN 546 (805)
1803 Q Consensus 469 pkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndy--sfiryytrtlyqfqfqealcqaakhegplhkcdisn 546 (805)
1804 +.+++.+.||+..++..|+..|.. + .-++.+.+|++.++ .+++|....++++|+.+++|+...+ +|++.| +.+
1805 T Consensus 378 ~~~~l~~~w~~~~~~y~g~~~~~~-~--~~~~~~~~H~~~~~~~Y~~~Y~~~~i~a~ql~~~~~~~~~~-~~~~~~-~~~ 452 (505)
1806 T 3DWC_B 378 EAEEVPRVWNEKMKSYLGLETLGN-D--KEGCLQDVHWSGGMFGYFPTYSLGAMVAAQLMSCVRRELGE-EVVDDC-IRK 452 (505)
1807 T ss_dssp CGGGHHHHHHHHHHHHHSCCCTTC-C--TTTTTSCSTTTTTCCSCTHHHHHHHHHHHHHHHHHHHHHCH-HHHHHH-HHT
1808 T ss_pred CHHHhhHHHHHHHHHHcCCCCCCC-C--cCCccccccccccccccchHHHHHHHHHHHHHHHHHHHHCc-ccHHHH-Hhc
1809 Confidence 999999999999999999876542 2 22568889988765 5789999999999999999998764 689999 543
1810
1811
1812 Q sp|Q9BYF1|ACE2 547 STEAGQKL----FNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFT 593 (805)
1813 Q Consensus 547 steagqkl----fnmlrlgksepwtlalenvvgaknmnvrpllnyfeplft 593 (805)
1814 .++|..+ -++++.|.+.+|.-.++.+.|. +++..+++.||+|+++
1815 T Consensus 453 -~~~~~~~~~l~~~~l~~G~s~~~~e~l~~~~G~-~l~~~~~~~~~~~~~~ 501 (505)
1816 T 3DWC_B 453 -GDLGKILAKQNEKIWQHGSSLTTDELLRQATGE-TLNPEHYRRHLERRYR 501 (505)
1817 T ss_dssp -TCCHHHHHHHHHHTGGGTTSSCHHHHHHHHHSS-SCCTHHHHHHHCCCCC
1818 T ss_pred -CCHHHHHHHHHHhhhhcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHh
1819 Confidence 7788876 4899999999999999999998 9999999999999885
1820
1821
1822 No 21
1823 >5WVU_C Thermostable carboxypeptidase 1 (E.C.3.4.17.19); carboxypeptidase, RIKEN Structural Genomics/Proteomics Initiative; HET: GOL; 2.6A {Thermus thermophilus HB8}
1824 Probab=100.00 E-value=8.4e-44 Score=344.00 Aligned_cols=469 Identities=20% Similarity=0.238 Sum_probs=368.7 Template_Neff=9.300
1825
1826 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPLQEIQNLTVKLQLQALQ 101 (805)
1827 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalq 101 (805)
1828 ++++..||++++.+...+-...++++|++.|++++.+.+.... ..++|+... .+.+.+-.++-+|..++
1829 T Consensus 3 ~~~~~~~L~~~~~~~~~~~~~~~~~~Wd~~t~~p~~~~~~r~~----------~~~~l~~~~-~~~~~~~~~~~~l~~~~ 71 (510)
1830 T 5WVU_C 3 PEAAYQNLLEFQRETAYLASLGALAAWDQRTMIPKKGHEHRAR----------QMAALARLL-HQRMTDPRIGEWLEKVE 71 (510)
1831 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCGGGHHHHHH----------HHHHHHHHH-HHHHTCHHHHHHHHHHT
1832 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCCCHhhHHHHHH----------HHHHHHHHH-HHhhcCHHHHHHHHHHc
1833 Confidence 4678899999999999999999999999999999887643322 123343332 34556677888888887
1834
1835
1836 Q sp|Q9BYF1|ACE2 102 QNGSSVLSEDKSKRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEV-GKQLRPLY 180 (805)
1837 Q Consensus 102 qngssvlsedkskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsev-gkqlrply 180 (805)
1838 .. ...+.+ ......++..|..+|...+ .++|.+.++|+++.++.+ ++|+.||... +..++|.+
1839 T Consensus 72 ~~-~~~~~~--~~~~~~~~~~~~~~~~~~~-----------~~~~~l~~~~~~~~~~~~--~~W~~~r~~~~~~~~~~~l 135 (510)
1840 T 5WVU_C 72 GS-PLVQDP--LSDAAVNVREWRQAYERAR-----------AIPERLAVELAQAESEAE--SFWEEARPRDDWRGFLPYL 135 (510)
1841 T ss_dssp TS-GGGSST--TSHHHHHHHHHHHHHHHHH-----------HSCHHHHHHHHHHHHHHH--HHHHHHHHHTCHHHHHHHH
1842 T ss_pred CC-CCCCCC--CHHHHHHHHHHHHHHHHHc-----------CCCHHHHHHHHHcccHHH--HHHHHHhhhCChhhhHHHH
1843 Confidence 65 333332 4455667888988888655 678999999999999998 7999999988 89999999
1844
1845
1846 Q sp|Q9BYF1|ACE2 181 EEYVVLKNEMARANHYE----------DYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1847 Q Consensus 181 eeyvvlknemaranhye----------dygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1848 +++|-++|++|+.+.|. ++.|||...|+ +|...++++..|++|+|++..||+|+|.+.
1849 T Consensus 136 ~~~v~l~~~~A~~~g~~~~~~~~~~~~~~~d~~l~~y~----------~~~~~~~l~~l~~~l~~~~~~l~~~~~~~~-- 203 (510)
1850 T 5WVU_C 136 KRVYALTKEKAEVLFALPPAPGDPPYGELYDALLDGYE----------PGMRARELLPLFAELKEGLKGLLDRILGSG-- 203 (510)
1851 T ss_dssp HHHHHHHHHHHHHHHTSCCSTTSCCCCSHHHHHHHHHS----------TTCCHHHHHHHHHHHHHHHHHHHHHHHTTC--
1852 T ss_pred HHHHHHHHHHHHHhhcCCCCCCCCCCCCHHHHHHHhcC----------CCCCHHHHHHHHHHHHHHHHHHHHHHHccC--
1853 Confidence 99999999999999997 99999988776 223358899999999999999999999964
1854
1855
1856 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGFWEN 330 (805)
1857 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwen 330 (805)
1858 |. | |+|++ .+.++..+.++-++++|.+.|+.. ++
1859 T Consensus 204 -~~----~----~~~~~-------------------------------~~~~~~~~~~~~~~~~~~~lG~~~------~~ 237 (510)
1860 T 5WVU_C 204 -KR----P----DTSIL-------------------------------HRPYPVEAQRRFALELLSACGYDL------EA 237 (510)
1861 T ss_dssp -CC----C----CGGGG-------------------------------GSCCCHHHHHHHHHHHHHHHTCCG------GG
1862 T ss_pred -CC----C----Cchhh-------------------------------cCCCCHHHHHHHHHHHHHHCCCCc------hh
1863 Confidence 21 1 44421 122223446778889999999886 12
1864
1865
1866 Q sp|Q9BYF1|ACE2 331 SMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTK--VTMDDFLTAHHEMGHIQYDMAYA----AQPFLLRNGANEGFHEAV 404 (805)
1867 Q Consensus 331 smltdpgnvqkavchptawdlgkgdfrilmctk--vtmddfltahhemghiqydmaya----aqpfllrnganegfheav 404 (805)
1868 +.+ | ..|||.+|+++.+|+||.+|.. .+++++.+.|||+||..|.+.+. -+| ++.+++.+|||+.
1869 T Consensus 238 ~~~-d------k~~~~f~~~~~~~d~rI~~~~~~~~~~~~~~~l~HE~GHa~~~~~~~~~~~~~~--~~~~~~~~~~E~~ 308 (510)
1870 T 5WVU_C 238 GRL-D------PTAHPFEIAIGPGDVRITTRYYEDFFNAGIFGTLHEMGHALYEQGLPKEHWGTP--RGDAVSLGVHESQ 308 (510)
1871 T ss_dssp CCE-E------ECSSCCEEEEETTEEEEEECCBTTBHHHHHHHHHHHHHHHHHHHTSCGGGTTSG--GGSCSCHHHHHHH
1872 T ss_pred CCC-C------CCCCCceeecCCCceEEEEeeecchhhHHHHHHHHHHHHHHHHcCCCHHHCCCC--CccCCCchhHHHH
1873 Confidence 211 1 5799999999989999999998 89999999999999999999874 355 4578999999999
1874
1875
1876 Q sp|Q9BYF1|ACE2 405 GEIMS----LSAATPKHLKS-----IGLLSPDFQEDNETEINF----LLKQALTIVGTLPFTYMLEKWRW--MVFKGEIP 469 (805)
1877 Q Consensus 405 geims----lsaatpkhlks-----igllspdfqedneteinf----llkqaltivgtlpftymlekwrw--mvfkgeip 469 (805)
1878 +..|. .+..++++|.. +|++++.-.++-...+|. ++++++..+. +|+.+++ +|+| -++.|+++
1879 T Consensus 309 S~~~E~~~~~~~~~~~~l~~~~~~~~~~l~~~~~~~~~~~~~~~~~~l~r~~~d~~~-~~~~~~~-~~~~e~~l~~~~~~ 386 (510)
1880 T 5WVU_C 309 SRTWENLVGRSLGFWERFFPRAREVFASLGDVSLEDFHFAVNAVEPSLIRVEADEVT-YNLHILV-RLELELALFRGELS 386 (510)
1881 T ss_dssp HHCCCCCCTTSHHHHHHHHHHHHHHCGGGTTCCHHHHHHHTTCCCCCSCSTTCCTTT-HHHHHHH-HHHHHHHHHHTSCC
1882 T ss_pred HHHHHHHhcCCHHHHHHHHHHHHHHhhccCCCCHHHHHHHHhccChhhhhHHhHHhH-hhHHHHH-HHHHHHHHhcCCCC
1883 Confidence 99998 66777777655 666544323333455666 7777777665 8998888 9999 89999999
1884
1885
1886 Q sp|Q9BYF1|ACE2 470 KDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSND--YSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDIS-- 545 (805)
1887 Q Consensus 470 kdqwmkkwwemkreivgvvepvphdetycdpaslfhvsnd--ysfiryytrtlyqfqfqealcqaakhegplhkcdis-- 545 (805)
1888 .+++-+.||++.++..|+..|. +...| ....|.+.. +.|.+|....++++|+.+++|+.. |+++.| +.
1889 T Consensus 387 ~~~l~~~w~~~~~~y~G~~~~~--~~~~~--~~~~h~~~~~~~Y~~~Y~~g~i~a~qi~~~~~~~~---~~~~~~-~~~~ 458 (510)
1890 T 5WVU_C 387 PEDLPEAWAEKYRDHLGVAPKD--YKDGV--MQDVHWAGGLFGYFPTYTLGNLYAAQFFQKAEAEL---GPLEPR-FARG 458 (510)
1891 T ss_dssp GGGHHHHHHHHHHHHHSCCCSS--STTTG--GGCSGGGGTCCSCTHHHHHHHHHHHHHHHHHHHHH---CCSHHH-HHTT
1892 T ss_pred hhhHhHHHHHHHHHHhCCCCCC--CCCCc--cccccccCCcccchHHHHHHHHHHHHHHHHHHHHH---CChhHH-hhcC
1893 Confidence 9999999999999999987553 23333 344555543 345588899999999999999876 489999 65
1894
1895
1896 Q sp|Q9BYF1|ACE2 546 NSTEAGQKLF-NMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWL 595 (805)
1897 Q Consensus 546 nsteagqklf-nmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwl 595 (805)
1898 +..++|+.|- ++++.|.+.+|.-.++.+.|. .++..+++.||++.+.-|
1899 T Consensus 459 ~~~~~g~~l~~~~l~~G~s~~~~ell~~~~G~-~l~~~~~l~~~~~~~~~~ 508 (510)
1900 T 5WVU_C 459 EFQPFLDWTRARIHAEGSRFRPRVLVERVTGE-APSARPFLAYLEKKYAAL 508 (510)
1901 T ss_dssp CCHHHHHHHHHHTGGGTTSSCHHHHHHHHHSS-CCCSHHHHHHHHHHHHHH
1902 T ss_pred CcHHHHHHHHHhHHHcccCCCHHHHHHHHHCC-CCCHHHHHHHHHHHHHHH
1903 Confidence 4478999987 899999999999999999998 899999999999987644
1904
1905
1906 No 22
1907 >3SKS_A Putative Oligoendopeptidase F; Structural Genomics, Center for Structural; HET: PO4; 2.05A {Bacillus anthracis}
1908 Probab=100.00 E-value=1.7e-38 Score=300.72 Aligned_cols=506 Identities=15% Similarity=0.182 Sum_probs=375.4 Template_Neff=10.400
1909
1910 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQST-LA----QMYPLQEIQNLTVKLQ 96 (805)
1911 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqst-la----qmyplqeiqnltvklq 96 (805)
1912 ++++..+|..++.....+-...+.++|.|.+++|.+..+.+.......+..+..... +. +--+++++.. ..+-+
1913 T Consensus 36 ~~~l~~~l~~~e~~~~~~~~~~~~a~~~~~~d~~d~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~~~~~l~~-~~~~~ 114 (567)
1914 T 3SKS_A 36 VEEQKQVIHSINEIRNDFGTMGNLCYIRHSVDTTDAFYKEEQDFFDEFSPVVQGYGTKYYNALIHSPFREELEA-YYGKQ 114 (567)
1915 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHhHHhHHHHHHHHHHHhcChhHHHHHH-HHHHH
1916 Confidence 456778899999888888899999999999999999877665544444433322211 11 1112222211 12335
1917
1918
1919 Q sp|Q9BYF1|ACE2 97 LQALQQNGSSVLSEDKS---KRLNTILNTMSTIYSTGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRSEVG 173 (805)
1920 Q Consensus 97 lqalqqngssvlsedks---krlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrsevg 173 (805)
1921 ++.+.+.+...++++.. ..++.+.+.+..++++.++|.++ +++.+ +.+..+|++ -|...|-.+|++|+...+
1922 T Consensus 115 l~~~~~~~~~~l~e~~e~~l~~~~~~~~~~~~~~~~~~~~~~g---~~~~~-~~~~~~l~~-~d~~~R~~~~~a~~~~~~ 189 (567)
1923 T 3SKS_A 115 LFALAECDLKTYSDEVVKDLQLENKLSSQYTQLLASAKIDFAG---EERTL-SQLIPFMQG-KERSERKAASEAYYGFLA 189 (567)
1924 T ss_pred HHHHHHHHhhcCCHHHHHHHHHHHHHHHHHHHHHhcCEEEeCC---EEEeH-HHHHHHHhC-CCHHHHHHHHHHHHHHHh
1925 Confidence 55566666666666422 23456668888999999999773 56666 889999996 899999999999998766
1926
1927
1928 Q sp|Q9BYF1|ACE2 174 K---QLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAKLMN 250 (805)
1929 Q Consensus 174 k---qlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmn 250 (805)
1930 + .+++++.++|-+.+++|+.+.|.+|.+||.-.. .+.+|+...+..-++...++++|+|+.+|+++|.++-.
1931 T Consensus 190 ~~~~~~~~~l~~lv~~r~~~A~~~Gy~~~~~~~l~~~-----~~~~~~~~~~~~~l~~l~~~~~p~~~~~~~~~~~~lg~ 264 (567)
1932 T 3SKS_A 190 ENEEELDRIYDELVKVRTKIAKSLGFKNFVELGYARM-----YRTDYNAEMVANYRQQVLDYIVPVTTELRKRQQARIGV 264 (567)
1933 T ss_pred cCccchHHHHHHHHHHHHHHHHHcCCCCHHHHHHHHh-----hhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCC
1934 Confidence 5 579999999999999999999999999997432 23455555555566666777999999999998876510
1935
1936
1937 Q sp|Q9BYF1|ACE2 251 AYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFG-QKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLP------NM 323 (805)
1938 Q Consensus 251 aypsyispigclpahllgdmwgrfwtnlysltvpfg-qkpnidvtdamvdqawdaqrifkeaekffvsvglp------nm 323 (805)
1939 .++ +.|...+.++ .+ ..| .+....+++.++.+|-+.|.. .|
1940 T Consensus 265 -------------~~l------~~~d~~~~~~--~~~~~~-----------~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 312 (567)
1941 T 3SKS_A 265 -------------EKL------AYYDENFEFP--TGNPTP-----------KGDADWIVNHGKTMYKELSAETDEFFNFM 312 (567)
1942 T ss_pred -------------CCC------CcccccCCCC--CCCCCC-----------CCCHHHHHHHHHHHHHhhCHHHHHHHHHH
1943 Confidence 011 3443333221 11 112 223457788888888888875 46
1944
1945
1946 Q sp|Q9BYF1|ACE2 324 TQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAA-QPFLLRNGANEGFHE 402 (805)
1947 Q Consensus 324 tqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaa-qpfllrnganegfhe 402 (805)
1948 ...+|-+ ....||....+.|++.. +.++++|+||...+.+|+.+.+|||||..+.+.... +|+..+. .+.+|+|
1949 T Consensus 313 ~~~~~iD-~~~r~~K~~g~~~~~~~---~~~~~~i~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~-~~~~~~E 387 (567)
1950 T 3SKS_A 313 LDNDLLD-LVAKKGKAGGGYCTYIE---NYKAPFIFSNFNGTSGDIDVLTHEAGHAFQVYESRKFEIPEYNW-PTYEACE 387 (567)
1951 T ss_pred ccccccc-cCCCCCCCCCceeecCC---CCCCCEEEEeCCCCHHHHHHHHHHHHHHHHHHHccCCCCCCCCC-CCHHHHH
1952 Confidence 6667765 44556777778999854 457899999999999999999999999998887654 4554555 4568999
1953
1954
1955 Q sp|Q9BYF1|ACE2 403 AVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFK-GEIPKDQWMKKWWEMK 481 (805)
1956 Q Consensus 403 avgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfk-geipkdqwmkkwwemk 481 (805)
1957 +++..|.+....+ |... +..+. + ..++.+++..+.++|+.+++.+|+|.++. |+++.+++-+.||+..
1958 T Consensus 388 ~~S~~~E~l~~~~--l~~~------~~~~~--~-~~l~~~~~~~~~~l~~~~~~~~~e~~~~~~~~~~~~~~~~~~~~~~ 456 (567)
1959 T 3SKS_A 388 IHSMSMEFFTWPW--MKLF------FEEDA--D-KYYFSHLSSALLFLPYGVSVDEYQHYVYENPEASPEERKTAWRNIE 456 (567)
1960 T ss_pred HHHHHHHHHhHHH--HHHh------CCCHH--H-HHHHHHHHHHHhHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
1961 Confidence 9999888877644 4321 11111 2 37888899999999999999999999997 8898899999999999
1962
1963
1964 Q sp|Q9BYF1|ACE2 482 REIVGVVEPVPHD--ETYCDPASLFHVS-NDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFNML 558 (805)
1965 Q Consensus 482 reivgvvepvphd--etycdpaslfhvs-ndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnml 558 (805)
1966 ++.-|++.|.+.+ +..+++++..|+. .....+.|....+.++|+.+.+|.. +.++|.++.++|
1967 T Consensus 457 ~~y~g~~~~~~~~~~~~~~~w~~~~h~~~~~~y~~~Y~~~~~~a~~l~~~~~~~--------------~~~~~~~~~~~l 522 (567)
1968 T 3SKS_A 457 KKYLPHRDYEDNDYLERGGFWQRQGHIYSSPFYYIDYTLAQICALQFWKRARDN--------------RQEAWEDYVNLC 522 (567)
1969 T ss_pred HHHCCCCCCCCCCCccccCChhhCCccccCCchHHHHHHHHHHHHHHHHHHHHc--------------cHHHHHHHHHHH
1970 Confidence 9999987776654 5677888888887 4677889999999999999999874 246789999999
1971
1972
1973 Q sp|Q9BYF1|ACE2 559 RLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNK 600 (805)
1974 Q Consensus 559 rlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnk 600 (805)
1975 +.|.+.||.-.++.+.|.....-..+.+++++|-.|++.+|.
1976 T Consensus 523 ~~G~s~~~~e~l~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~ 564 (567)
1977 T 3SKS_A 523 QQGGSKSFLELVEVANLTSPFAEGCVKSVITEIEAWLHAIDD 564 (567)
1978 T ss_pred HccCCCCHHHHHHHcCCCCCCChhHHHHHHHHHHHHHHHhhh
1979 Confidence 999999999999988776555566788899999999987663
1980
1981
1982 No 23
1983 >3AHN_A Oligopeptidase; HYDROLASE, HYDROLASE-HYDROLASE INHIBITOR complex; HET: ACT, 3A1; 1.8A {Geobacillus sp. MO-1}
1984 Probab=100.00 E-value=2.6e-38 Score=299.31 Aligned_cols=505 Identities=14% Similarity=0.150 Sum_probs=360.1 Template_Neff=10.400
1985
1986 Q sp|Q9BYF1|ACE2 22 EEQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNN----AGDKWSAFLKEQ-STLAQMYPLQEIQNLTVKLQ 96 (805)
1987 Q Consensus 22 eeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnn----agdkwsaflkeq-stlaqmyplqeiqnltvklq 96 (805)
1988 ++++..+++.++.....+-...++++|.|.+|+|.+..+.+.. ...++...+.+. ..+.+-..++ .+. +-.
1989 T Consensus 33 ~~~~~~~l~~~e~~~~~~~~~~~~a~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~---~~~-~~~ 108 (564)
1990 T 3AHN_A 33 AEEQNEAMKEINQLRNDFSTMAQICYIRHTIDTNDEFYKQEQDFFDEVEPIVKGLVNDYYRALVSSPFRS---QLE-GKW 108 (564)
1991 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCTTHH---HHH-HHH
1992 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCchHH---HHh-hhh
1993 Confidence 4677788888888888888999999999999999988775432 222333332211 0111100011 110 011
1994
1995
1996 Q sp|Q9BYF1|ACE2 97 LQALQQNGSSV--LSEDKSKRLNTILNTMSTIYS----TGKVCNPDNPQECLLLEPGLNEIMANSLDYNERLWAWESWRS 170 (805)
1997 Q Consensus 97 lqalqqngssv--lsedkskrlntilntmstiys----tgkvcnpdnpqeclllepglneimansldynerlwaweswrs 170 (805)
1998 +..+.+..... ..+++-..+......++..|+ +.++|-.+ +++.+ +.+..+|. +-|...|-.+|++|+.
1999 T Consensus 109 ~~~~~~~~~~~l~~~~~~~~~~~~~~~~l~~~y~~~~~~~~~~~~g---~~~~~-~~~~~~~~-~~d~~~R~~~~~~~~~ 183 (564)
2000 T 3AHN_A 109 GKQLFALAEAELKTYSPDIVEDLQLENKLTSEYTKLVASAKIFFEG---EERTL-AQLQPFVE-SPDRDMRKRASEARFT 183 (564)
2001 T ss_dssp CTHHHHHHHHHHTTCCGGGHHHHHHHHHHHHHHHHHHHTCCEEETT---EEECT-GGGHHHHT-CSSHHHHHHHHHHHHH
2002 T ss_pred HHHHHHHHHHHhhhcChhhHHHHHHHHHHHHHHHHHHhccEEEeCC---EEEeH-HHHHHHhc-CCCHHHHHHHHHHHHH
2003 Confidence 11111111111 223333444444556666666 88888542 35555 88999986 8899999999999999
2004
2005
2006 Q sp|Q9BYF1|ACE2 171 EVGK---QLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYEHLHAYVRAK 247 (805)
2007 Q Consensus 171 evgk---qlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvrak 247 (805)
2008 ..++ .++++|.+.|-+++++|+.+.|.+|.+||...+. ..+++...+..-++...++++|+|+.+++++|..
2009 T Consensus 184 ~~~~~~~~~~~~~~~lv~~r~~~A~~~Gy~~~~~~~l~~~~-----~~~~~~e~~~~~~~~l~~~~~p~~~~~~~~~~~~ 258 (564)
2010 T 3AHN_A 184 FFQEHEEKFDEIYDQLVKVRTAIAQKLGFKNFVELGYARLG-----RTDYNAEMVAKFRKQVEKHIVPIAVKLRERQRER 258 (564)
2011 T ss_dssp HHHHTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHHHTT-----CCSCCHHHHHHHHHHHHHHTHHHHHHHHHHHHHH
2012 T ss_pred HHHHCHHHHHHHHHHHHHHHHHHHHHcCCCCHHHHHHHHcc-----cCCCCHHHHHHHHHHHHHhchHHHHHHHHHHHHH
2013 Confidence 8876 6999999999999999999999999999964321 1345555555556666778899999999988864
2014
2015
2016 Q sp|Q9BYF1|ACE2 248 LMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVSVGLPNMTQGF 327 (805)
2017 Q Consensus 248 lmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvglpnmtqgf 327 (805)
2018 + |...-+.|... .||.....++. .++..+|+.++++|.+ ++.+...|
2019 T Consensus 259 l-------------------g~~~~~~~d~~----~~~~~~~~~~~--------~~~~~~~~~~~~~~~~--~~~~~~~~ 305 (564)
2020 T 3AHN_A 259 I-------------------GVEKLKYYDEA----FVFPTGNPMPK--------GDANWIIENGKKMYEE--LSPETGEF 305 (564)
2021 T ss_dssp H-------------------TCSSCCTTTTT----CCCTTCCCCCS--------SCHHHHHHHHHHHHHH--HCHHHHHH
2022 T ss_pred H-------------------Ccccccccccc----ccCCCCCCCCC--------CCHHHHHHHHHHHHHH--hCHHHHHH
2023 Confidence 3 32222334322 23332211111 1455677788888866 44455677
2024
2025
2026 Q sp|Q9BYF1|ACE2 328 WENSM-------LTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEGF 400 (805)
2027 Q Consensus 328 wensm-------ltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegf 400 (805)
2028 |++.. ...||....+.|++.. ..+++||+||...+++|+.+.+||+||.++.+.+..++.+..++.+.+|
2029 T Consensus 306 ~~~~~~~~~~D~~~r~~K~~g~~~~~~~---~~~~~~i~~n~~~~~~~~~tl~HE~GHa~h~~~~~~~~~~~~~~~~~~~ 382 (564)
2030 T 3AHN_A 306 FRYMIEHELMDLVAKKGKASGGYCTYIE---NYKAPFIFSNFTGTSGDIDVLTHEAGHAFQVYESRHYEIPEYNWPTLEA 382 (564)
2031 T ss_dssp HHHHHHTTCEEEECCTTCCSSCEEEEEG---GGTEEEEEEEECSSTHHHHHHHHHHHHHHHHHHTTTCSSGGGSSCCHHH
2032 T ss_pred HHHHHHcCCcccccCCCCCCCceeeeec---CCCCcEEEEcCCCChhHHHHHHHHHHHHHHHHHccCCCCccccCCcHHH
2033 Confidence 77652 2345555568999865 3577899999999999999999999999998877666655556788999
2034
2035
2036 Q sp|Q9BYF1|ACE2 401 HEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFK-GEIPKDQWMKKWWE 479 (805)
2037 Q Consensus 401 heavgeimslsaatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfk-geipkdqwmkkwwe 479 (805)
2038 +|+.+..|.+....+ |+.. ++ +... ..++.+++.++..+|+.+++..|+|-++. |.++.+++-+.||+
2039 T Consensus 383 ~E~~s~~~e~l~~~~--l~~~--~~-----~~~~--~~~~~~l~~~~~~l~~~~~~~~fe~~ly~~~~~~~~~~~~~~~~ 451 (564)
2040 T 3AHN_A 383 CEIHSMSMEFFTWPW--MKLF--FK-----EDAE--KYQFYHLSDALLFLPYGVAVDEFQHFVYENPNATPAERKQAWRA 451 (564)
2041 T ss_dssp HHHHHHHHHHHTGGG--HHHH--HG-----GGHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCCHHHHHHHHHH
2042 T ss_pred HHHHHHHHHHhhHHH--HHHH--cc-----chHH--HHhHHHHHHHHHHHHHHHHHHHHHHHHHhCCCCCHHHHHHHHHH
2043 Confidence 999999988877644 4431 11 1111 13445566778889999999999999999 88888999999999
2044
2045
2046 Q sp|Q9BYF1|ACE2 480 MKREIVGVVEPVPHD--ETYCDPASLFHVSN-DYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFN 556 (805)
2047 Q Consensus 480 mkreivgvvepvphd--etycdpaslfhvsn-dysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfn 556 (805)
2048 +..+..|++.|.+.+ +..+++.+..|+.. ....+.|....+.++|+.+.+|+. +.++|.++.+
2049 T Consensus 452 ~~~~y~g~~~~~~~~~~~~~~~w~~~~H~~~~~~yy~~Y~~s~~~a~~l~~~~~~~--------------~~~~~~~~~~ 517 (564)
2050 T 3AHN_A 452 IERKYMPTKDYDGNDYLERGGFWQRQSHIYTTAFYYIDYTLAQICAFQFWKRSREN--------------YKEAWNDYLT 517 (564)
2051 T ss_dssp HHHHHSTTCCCTTCHHHHTTCGGGGCHHHHHSTTTTHHHHHHHHHHHHHHHHHHHC--------------HHHHHHHHHH
2052 T ss_pred HHHHHCCCCCCCCCchhhcCCChhhccchhcCchHHHHHHHHHHHHHHHHHHHHHh--------------HHHHHHHHHH
2053 Confidence 999998876665544 56778888889875 556788999999999999988865 2568999999
2054
2055
2056 Q sp|Q9BYF1|ACE2 557 MLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKN 601 (805)
2057 Q Consensus 557 mlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnkn 601 (805)
2058 +|+.|.+.||.-.++.+-|...+...+++.||+||..||+.+|+-
2059 T Consensus 518 ~l~~G~s~~~~e~l~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~ 562 (564)
2060 T 3AHN_A 518 LCRQGGSKPFTELVRVANLISPFEDGCVQSVVGGIEGWLNSVDDQ 562 (564)
2061 T ss_dssp HHTTTTSSCHHHHHHHTTCCCTTSTTHHHHHHHHHHHHHTTSCGG
2062 T ss_pred HHhcCCCCCHHHHHHHCCCCCCCChhHHHHHHHHHHHHHhccccc
2063 Confidence 999999999999999977767899999999999999999998864
2064
2065
2066 No 24
2067 >2QR4_A Peptidase M3B, oligoendopeptidase F; structural genomics, oligoendopeptidase F, PSI-2; 2.5A {Enterococcus faecium}
2068 Probab=99.95 E-value=2e-33 Score=267.60 Aligned_cols=506 Identities=14% Similarity=0.121 Sum_probs=318.6 Template_Neff=10.400
2069
2070 Q sp|Q9BYF1|ACE2 23 EQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNN-AGDKWSAFLKEQSTLAQM---YPLQ---E-----IQN 90 (805)
2071 Q Consensus 23 eqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnn-agdkwsaflkeqstlaqm---yplq---e-----iqn 90 (805)
2072 +..+.+|+.++.....+-...+.+.|.+.++++.+..+.+.. ...+.+.+.+..+.+.+. .|.. + .+.
2073 T Consensus 34 ~~l~~~l~~~e~~~~~l~~~~~ya~~~~~~d~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~l~~~~~~~~l~~~~~l 113 (587)
2074 T 2QR4_A 34 SQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSLFSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKL 113 (587)
2075 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCHHHHHHHHHHHHHHHHHHHHTTTHHHHHTTSCHHHHHHHHHHCGGG
2076 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHhcchhHHHHcCCHHHHHHHHHhChhh
2077 Confidence 455666777777777788889999999999999986665443 333333333322222111 1111 1 112
2078
2079
2080 Q sp|Q9BYF1|ACE2 91 LTVKLQLQALQQNGSSVLSEDKSKRLNTI---LNTMSTIYSTG---KVCNPD----NPQECLLLEPGLNEIMANSLDYNE 160 (805)
2081 Q Consensus 91 ltvklqlqalqqngssvlsedkskrlnti---lntmstiystg---kvcnpd----npqeclllepglneimansldyne 160 (805)
2082 -..+-.|+.+.+.+...|+++..+.+.++ ++.++.+|++- .+|-++ +..++-+-.+.+..+|+ +-|...
2083 T Consensus 114 ~~~~~~l~~~~~~~~~~Ls~~~e~~l~~~~~~~~~~~~~y~~~~~~~~~~~~~~~~~g~~~~l~~~~~~~~l~-~~d~~~ 192 (587)
2084 T 2QR4_A 114 EVYRHYIQQIVDNRAHVLSAEQESLLAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLE-STDRRV 192 (587)
2085 T ss_dssp GGGHHHHHHHHTTGGGCCCHHHHHHHHHTHHHHHHHHHHHHHCCCCCCCCCEEECTTSCEEECCHHHHHHHHT-CSCHHH
2086 T ss_pred HhhHHHHHHHHHcCCcCCCHHHHHHHHHHhhhhHHHHHHHHHHHhhccccCcccCCCCcEEEcCHHHHHHHhh-CCCHHH
2087 Confidence 25566777788888899999988877666 77888899884 666552 23333333456888999 899999
2088
2089
2090 Q sp|Q9BYF1|ACE2 161 RLWAWESWRSEVG---KQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLY 237 (805)
2091 Q Consensus 161 rlwaweswrsevg---kqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikply 237 (805)
2092 |..+|++|++..+ ..+.++|.+++.+.+++|+.+.|.+|.+||..++++. -+.++..++.|++++
2093 T Consensus 193 R~~~~~a~~~~~~~~~~~~~~~l~~lv~~~~~~A~~~Gy~~~~~~~l~~~~~~------------~~~~~~l~~~i~~~~ 260 (587)
2094 T 2QR4_A 193 REAAFKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIP------------ESVYDTLVDVVNKHL 260 (587)
2095 T ss_dssp HHHHHHHHHHHHHHTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHHTTTCC------------HHHHHHHHHHHHHTH
2096 T ss_pred HHHHHHHHHHHHHHhHHHHHHHHHHHHHhhHHHHHHcCCCCHHHHHHhhcCCC------------HHHHHHHHHHHHHhh
2097 Confidence 9999999998876 4899999999999999999999999999997765531 144557788999999
2098
2099
2100 Q sp|Q9BYF1|ACE2 238 EHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQ--KPNIDVTDAMVDQAWDA-----QRIFKE 310 (805)
2101 Q Consensus 238 ehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgq--kpnidvtdamvdqawda-----qrifke 310 (805)
2102 ..+|+|+|.++.. + |. + . -+.|.. | .|+.. .+.+++ +..++....+ ..+++-
2103 T Consensus 261 ~~~~~~~~~~~~~-~-------g~-~-~------l~~~D~-~---~~~~~~~~~~~~~-~e~~~~~~~~~~~~~~~~~~~ 319 (587)
2104 T 2QR4_A 261 PLLHRYMELRKRL-L-------EV-E-K------LHMYDL-Y---TPVLGEAPITFTY-EEAKEKALEALKPMGEEYMAI 319 (587)
2105 T ss_dssp HHHHHHHHHHHHH-H-------TC-S-S------BCGGGS-S---SCSSCCCCC------CCHHHHHHHTGGGHHHHHHC
2106 T ss_pred HHHHHHHHHHHHH-h-------CC-C-C------cchhhc-C---CCCCCCCCCccCH-HHHHHHHHHHhHhhCHHHHHH
2107 Confidence 9999999876542 1 11 0 0 022322 1 22222 244554 2233332222 234444
2108
2109
2110 Q sp|Q9BYF1|ACE2 311 AEKFFVSVGLPNMTQGFWENSMLTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYA-AQP 389 (805)
2111 Q Consensus 311 aekffvsvglpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmaya-aqp 389 (805)
2112 ++++| +.| |-. +...||....+.|++.. .++++|+||...+.+|+.|.+||+||..+.+... .+|
2113 T Consensus 320 ~~~~~-~~~--------~id-~~~r~~K~~g~~~~~~~----~~~~~I~~~~~~~~~~~~tl~HE~GHa~h~~~~~~~~~ 385 (587)
2114 T 2QR4_A 320 VEKAF-SER--------WID-VVENKGKRSGAYSSGSY----DTNPYILLNWHDTLDQLFTLVHEMGHSVHSYFTRSNQP 385 (587)
2115 T ss_dssp ------------------------------------------------------CHHHHHHHHHHHHHHHHHHHC-----
2116 T ss_pred HHHHH-HcC--------CeE-eecCCCCCCCceecCCC----CCCcEEEeecCCChHHHHHHHHHHHHHHHHHHhhcCCC
2117 Confidence 55544 333 211 11134555567787643 3589999999999999999999999999988776 678
2118
2119
2120 Q sp|Q9BYF1|ACE2 390 FLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALTI-VGTLPFTYMLEKWRWMVFKG-- 466 (805)
2121 Q Consensus 390 fllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqalti-vgtlpftymlekwrwmvfkg-- 466 (805)
2122 .+.+. .+.+|+|+++..|..-... + |+. .+ +...+++.+++++++- +++++...+...|.+-++.+
2123 T Consensus 386 ~~~~~-~~~~~~E~~S~~~E~l~~~--~-----L~~-~~--~~~~~~~~l~~~~l~~~~~~l~~~~~~~~fe~~~~~~~~ 454 (587)
2124 T 2QR4_A 386 YVYGD-YSIFLAEIASTTNENILTE--Y-----LLE-TE--KDPRVRAYVLNHYLDGFKGTVFRQTQFAEFEHFMHTEDE 454 (587)
2125 T ss_dssp --------CHHHHHHHHHHHHHHHH--H-----HHH-HC--CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
2126 T ss_pred hhhcc-CcHHHHHHHHHHHHHHHHH--H-----HHH-hC--CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
2127 Confidence 87775 6778888888777654322 2 321 11 1223478888888763 67888888888888888876
2128
2129
2130 Q sp|Q9BYF1|ACE2 467 ---EIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCD 543 (805)
2131 Q Consensus 467 ---eipkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcd 543 (805)
2132 .++.+.+.+-||+..++..|+..|.. ++..++....+|....|-...|..-.+.++|+.+.+|+.
2133 T Consensus 455 ~~~~l~~~~l~~~~~~~~~~~~g~~~~~~-~~~~~~w~~~~h~~~~~Y~~~y~~~~~~~~~l~~~~~~~----------- 522 (587)
2134 T 2QR4_A 455 KGVPLTSEYLSDSYGKLNAKYYGPAVEED-PEIKFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQ----------- 522 (587)
2135 T ss_dssp TTCCCCHHHHHHHHHHHHHHHHCTTBCCC-GGGGGGGGGCGGGGSSSCTHHHHHHHHHHHHHHHHHHTT-----------
2136 T ss_pred cCCCCCHHHHHHHHHHHHHHHhCCCCCCC-hhhccHhHcCcchhcccccHHHHHHHHHHHHHHHHHHhc-----------
2137 Confidence 56678899999999999999876653 334556666677664444455555566677777777762
2138
2139
2140 Q sp|Q9BYF1|ACE2 544 ISNSTEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKNSF 603 (805)
2141 Q Consensus 544 isnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsf 603 (805)
2142 +.++|.++..+|+.|.+.||.-.++. +|.......++..+|.|+-.||+..++..-
2143 T Consensus 523 ---~~~~~~~~~~~l~~G~s~~~~ell~~-~G~~~~~~~~~~~~~~~l~~~l~~~~~~~~ 578 (587)
2144 T 2QR4_A 523 ---EPEALENYLAYLKAGNSDYPVEVMKK-AGVDMTQAAYIEDAMSMFEQRLNELEELID 578 (587)
2145 T ss_dssp ---CTTHHHHHHHHHHHCSCSCHHHHHHH-TTCCTTSSHHHHHHHHHHHHHHHHHHHHHH
2146 T ss_pred ---ChHHHHHHHHHHHcCCCCCHHHHHHH-cCCCCCCcHHHHHHHHHHHHHHHHHHHHHH
2147 Confidence 36789999999999999999999997 999988888999999999999998876543
2148
2149
2150 No 25
2151 >2O36_A Thimet oligopeptidase (E.C.3.4.24.15); thermolysin-like domain, substrate-binding channel, HYDROLASE; 1.95A {Homo sapiens}
2152 Probab=99.92 E-value=5e-30 Score=254.55 Aligned_cols=518 Identities=16% Similarity=0.181 Sum_probs=335.6 Template_Neff=9.600
2153
2154 Q sp|Q9BYF1|ACE2 26 KTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP-------------LQEIQNLT 92 (805)
2155 Q Consensus 26 ktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp-------------lqeiqnlt 92 (805)
2156 ..++..++.....+....++++|.++++++++..+....+-.++++|..+..+-...|. +.+.+...
2157 T Consensus 47 ~~~v~~~d~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~ld~e~~r~ 126 (674)
2158 T 2O36_A 47 ESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 126 (674)
2159 T ss_dssp CCCCCHHHHHHHHHHHHHHHHHSHHHHCSCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHHHHSCTTCSCHHHHHH
2160 T ss_pred HHHHHHHHHhhHHHHHHHHHHhHHHHhCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHHHhhchhcCCHHHHHH
2161 Confidence 34566666667777888999999999999999999999999999999999877666665 23333445
2162
2163
2164 Q sp|Q9BYF1|ACE2 93 VKLQLQALQQNGSSVLSEDKSKRLNTI---LNTMSTIYSTGKVCNPD-------------------------NPQECLLL 144 (805)
2165 Q Consensus 93 vklqlqalqqngssvlsedkskrlnti---lntmstiystgkvcnpd-------------------------npqeclll 144 (805)
2166 ++..++.++++|.. |++++.+++..+ ++.+++.|+....|.+. .+ -++.+
2167 T Consensus 127 l~~~l~~~~~~G~~-L~~~~~~~~~~l~~~i~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~~-~~~~l 204 (674)
2168 T 2O36_A 127 LERLIKLGRRNGLH-LPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGK-LKVTL 204 (674)
2169 T ss_dssp HHHHHHHHHHTTTT-SCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECTTTTTTSCHHHHTTSEECTTSC-EEEES
2170 T ss_pred HHHHHHHHHHcCCC-CCHHHHHHHHHHHHHHHHHHHHHHHccCCCccccceeHHHhcCCCHHHHHHHHhhhCCC-EEEec
2171 Confidence 66677788888865 666565666555 55578888888777643 12 13333
2172
2173
2174 Q sp|Q9BYF1|ACE2 145 -EPGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLI 223 (805)
2175 Q Consensus 145 -epglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqli 223 (805)
2176 .|.+..+|+++-|...|..+|+.|+...++...+++++.+.+++++|+...|.+|.+||..+..+ .+..++.
2177 T Consensus 205 ~~~~~~~il~~~~d~~~R~~~~~a~~~~~~~~~~~~l~~ll~lR~~~A~llGy~s~~~~~l~~~~~-------~~~~~v~ 277 (674)
2178 T 2O36_A 205 KYPHYFPLLKKCHVPETRRKVEEAFNSRCKEENSAILKELVTLRAQKSRLLGFHTHADYVLEMNMA-------KTSQTVA 277 (674)
2179 T ss_dssp SHHHHHHHHHHCCCHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSTT-------CSHHHHH
2180 T ss_pred CChhhHHHHhhCCCHHHHHHHHHHHHcCCchHHHHHHHHHHHHHHHHHHHhCCCCHHHHHhhccCC-------CCHHHHH
2181 Confidence 57789999999999999999999998877788999999999999999999999999999764332 2233444
2182
2183
2184 Q sp|Q9BYF1|ACE2 224 EDVEHTFEEIKPLYEHLHAYVRAK---LMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQ 300 (805)
2185 Q Consensus 224 edvehtfeeikplyehlhayvrak---lmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdq 300 (805)
2186 +-++...+.++|+|+..++.+++. ....+.. +..+.+ ..|...|-...... ...++.++.+.+
2187 T Consensus 278 ~~l~~l~~~~~p~~~~~~~~l~~~~~~~~~~~g~--~~~~~l----------~~wD~~y~~~~~~~--~~~~~~~~~~~~ 343 (674)
2188 T 2O36_A 278 TFLDELAQKLKPLGEQERAVILELKRAECERRGL--PFDGRI----------RAWDMRYYMNQVEE--TRYCVDQNLLKE 343 (674)
2189 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTC--CCCSSC----------CTTTHHHHHHHHCC--CCCCCCHHHHGG
2190 T ss_pred HHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHCCC--CCCCCC----------ChhcHHHHHHHHHH--hccCCCHHHHHh
2191 Confidence 445555678899998876655442 2222210 001111 23444444443322 234444555555
2192
2193
2194 Q sp|Q9BYF1|ACE2 301 AWD----AQRIFKEAEKFFVSVGLPNM---TQGFWENSML-----------------T----DPGNVQKAVCHPTAWDLG 352 (805)
2195 Q Consensus 301 awd----aqrifkeaekffvsvglpnm---tqgfwensml-----------------t----dpgnvqkavchptawdlg 352 (805)
2196 .+. ...+++.++++| |+.-. ..-+|..+.. . .||....+.|++...+..
2197 T Consensus 344 yf~~~~v~~~l~~~~~~~f---g~~~~~~~~~~~W~~~v~~~~v~d~~~~~~lg~~ylD~~~r~~K~~~a~~~~~~~~~~ 420 (674)
2198 T 2O36_A 344 YFPVQVVTHGLLGIYQELL---GLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCL 420 (674)
2199 T ss_dssp GCBHHHHHHHHHHHHHHHH---TEEEEECTTCCCSSTTCEEEEEEETTTCCEEEEEEEECSCCTTSCCSCEEEEEECCEE
2200 T ss_pred hCCHHHHHHHHHHHHHHHh---CcEEEeCCCCCcccCCceEEEEEeCCCCcEEEEEEEeCCCCCCCCCCCceeeEeCCcc
2201 Confidence 443 245666666666 43221 2345665553 1 234433455554332211
2202
2203
2204 Q sp|Q9BYF1|ACE2 353 K--GDF-----RI---------LMCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGANEG--FHEAVGEIMSLSAAT 414 (805)
2205 Q Consensus 353 k--gdf-----ri---------lmctkvtmddfltahhemghiqydmayaaqpfllrnganeg--fheavgeimslsaat 414 (805)
2206 . |+. .| -.|+.++++|+.|.+||+||..+.+.+..++..+ .|.+-+ |+|+++.+|.+.+..
2207 T Consensus 421 ~~~~~~~~P~~~i~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~~~-~g~~~~~d~~E~~S~~~E~~~~~ 499 (674)
2208 T 2O36_A 421 RQDGSRQIAIAAMVANFTKPTADAPSLLQHDEVRTYFHEFGHVMHQLCSQAEFAMF-SGTHVETDFVEAPSQMLENWVWE 499 (674)
2209 T ss_dssp CTTSCEECEEEEEECCCCCCBTTBCCBCCHHHHHHHHHHHHHHHHHHHCCCSSGGG-STTCSCTTTTTHHHHHHHGGGGS
2210 T ss_pred cCCCCeeceEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhcCCcccc-cCCcccchhhcchhHHHHHhhcC
2211 Confidence 0 111 22 1578888999999999999999999988766554 566655 999999999999999
2212
2213
2214 Q sp|Q9BYF1|ACE2 415 PKHLKSIGLLSPDFQEDNETEINFLLKQALTIVGTLPFTYMLEKWRWMVFKGEIP---KDQWMKKWWEMKREIVGVVEPV 491 (805)
2215 Q Consensus 415 pkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeip---kdqwmkkwwemkreivgvvepv 491 (805)
2216 |++|+.++.-..+-+.-.+..++.++.. ....+..++++.+.+-.|..++- .+++.+.||++.++..|+ |+
2217 T Consensus 500 ~~~L~~l~~~~~~~~~l~~~~~~~l~~~----~~~~~~~~~~~~~~~~~~d~~l~~~~~~~~~~~~~~l~~~~~g~--~~ 573 (674)
2218 T 2O36_A 500 QEPLLRMSRHYRTGSAVPRELLEKLIES----RQANTGLFNLRQIVLAKVDQALHTQTDADPAEEYARLCQEILGV--PA 573 (674)
2219 T ss_dssp HHHHHHTCCCTTTCCCCCHHHHHHHHHG----GGTTHHHHHHHHHHHHHHHHHHTTCSSCCHHHHHHHHCCCCCSS--CC
2220 T ss_pred hHHHHHHcccCCCCCCCCHHHHHHHHHH----hhHhHHHHHHHHHHHHHHHHHHhCCCCCCHHHHHHHHHHHHhCC--CC
2221 Confidence 9999988743221111112233333321 11222222333444434433332 356889999999999887 33
2222
2223
2224 Q sp|Q9BYF1|ACE2 492 PHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQ-AAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLA 569 (805)
2225 Q Consensus 492 phdetycdpaslfhvsndysfiryytrtlyqfqfqealcq-aakhegplhkcdisnsteagqklf-nmlrlgksepwtla 569 (805)
2226 +. ...++.+..|+..+|.+ .|| .-++..-+...+.+ ..+..||+ +.++|.++. ++|..|.+.+|.-.
2227 T Consensus 574 ~~--~~~~~~~~~Hl~~~y~~-~yy-~Yl~s~vlA~~i~~~~f~~~~~~-------~~~~g~~~~~~~L~~G~s~~~~e~ 642 (674)
2228 T 2O36_A 574 TP--GTNMPATFGHLAGGYDA-QYY-GYLWSEVYSMDMFHTRFKQEGVL-------NSKVGMDYRSCILRPGGSEDASAM 642 (674)
2229 T ss_dssp CT--TCCGGGGCGGGGTTCTT-CTT-HHHHHHHHHHHHCCCCCCHHCTT-------CHHHHHHHCCCCCTTGGGSCHHHH
2230 T ss_pred CC--CCCCcccHHHHHhcchH-HHH-HHHHHHHHHHHHHHHHHHhhCCC-------CHHHHHHHHHhccccCCCcCHHHH
2231 Confidence 32 24577888898766655 344 22222111111111 11223343 458899999 89999999999999
2232
2233
2234 Q sp|Q9BYF1|ACE2 570 LENVVGAKNMNVRPLLNYF 588 (805)
2235 Q Consensus 570 lenvvgaknmnvrpllnyf 588 (805)
2236 ++++.|. .++..+++.++
2237 T Consensus 643 l~~~lG~-~~~~~~~l~~~ 660 (674)
2238 T 2O36_A 643 LRRFLGR-DPKQDAFLLSK 660 (674)
2239 T ss_dssp HHHHHSS-CCCSHHHHHHT
2240 T ss_pred HHHHhCC-CCCHHHHHHHc
2241 Confidence 9999995 78888888765
2242
2243
2244 No 26
2245 >3CE2_A Crystal structure of putative peptidase; structural genomics, UNKNOWN FUNCTION, putative; 2.6A {Chlamydophila abortus}
2246 Probab=99.92 E-value=1.1e-29 Score=244.31 Aligned_cols=507 Identities=15% Similarity=0.108 Sum_probs=330.6 Template_Neff=10.300
2247
2248 Q sp|Q9BYF1|ACE2 23 EQAKTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGD-KWSAFLKEQSTL---AQMYPLQEI-------QNL 91 (805)
2249 Q Consensus 23 eqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagd-kwsaflkeqstl---aqmyplqei-------qnl 91 (805)
2250 +..+.+++.+......+-...+.+++.+.++.+.+..+.+.+... ..+.+...-+.+ .+..+-+++ +.-
2251 T Consensus 67 ~~~~~~l~~~e~~~~~l~~~~~~a~~~~~~d~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~l~~~~~~ 146 (618)
2252 T 3CE2_A 67 ESLLSLLTTLFSIERKLNKLYVYAHLTHDQDITNQEGIADLKSITHLHTLFAEETSWVQPALTSLSESLIAQHLSAPCLA 146 (618)
2253 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCTTCHHHHHHHHHHHHHHHHHHHHTTTHHHHHHTSCHHHHHHHHHCSTTG
2254 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHhhhhhHHHHhcCCHHHHHHHhcCccch
2255 Confidence 455667777777778888889999999999998876665554333 222222211111 011111111 223
2256
2257
2258 Q sp|Q9BYF1|ACE2 92 TVKLQLQALQQNGSSVLSEDKSKRLNTI---LNTMSTIYST---GKVCNPD---NPQECLLLEPG-LNEIMANSLDYNER 161 (805)
2259 Q Consensus 92 tvklqlqalqqngssvlsedkskrlnti---lntmstiyst---gkvcnpd---npqeclllepg-lneimansldyner 161 (805)
2260 ..+..|+.+...+...|++++.+++..+ +..++.+|++ ..+|-+. ...+++-+.++ ...+|. +-|...|
2261 T Consensus 147 ~~~~~l~~~~~~~~~~Ls~~~e~~l~~l~~~l~~~~~~~~~l~~~~~~~~~~~~~~g~~~~l~~~~~~~~l~-~~d~~~R 225 (618)
2262 T 3CE2_A 147 PYRFYLEKIFRLSIHTGTPGEEKILASAFTPLEVASKAFSSLSDSEIPFGQATDSEGNSHPLSHALASLYMQ-STDRELR 225 (618)
2263 T ss_dssp GGHHHHHHHHTTGGGCCCHHHHHHHHHHTTGGGHHHHHHHCCCCCCSCCCEEECSSCCEEECCHHHHHHHHT-CSCHHHH
2264 T ss_pred hhHHHHHHHHHhCCccCCHHHHHHHHHhcChhHHHHHHHHHHHcccccccceeCCCCCEEECCHHHHHHHcc-CCCHHHH
2265 Confidence 4566777766667777888877665544 4466666765 4555431 12245555655 677777 8899999
2266
2267
2268 Q sp|Q9BYF1|ACE2 162 LWAWESWRSEV---GKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYE 238 (805)
2269 Q Consensus 162 lwaweswrsev---gkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplye 238 (805)
2270 --+|+.|.... .....+++.+.+-+++++|+...|.+|.+|+..+++++ -+.++..++.|++++.
2271 T Consensus 226 k~~~~a~~~~~~~~~~~~~~~l~~l~~~r~~~A~~~Gy~s~~~~~l~~~~~~------------~~~~~~l~~~v~~~~~ 293 (618)
2272 T 3CE2_A 226 KTSYLAQCERYHSYRHTFANLLNGKIQAHVFYAKNKRYNSCLQAALYHNNIP------------TTVYTNLIDIVKKNSS 293 (618)
2273 T ss_dssp HHHHHHHHHHHHTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTTTCC------------HHHHHHHHHHHHTTHH
2274 T ss_pred HHHHHHHHHHHHhcHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHhcCCC------------HHHHHHHHHHHHHchH
2275 Confidence 99999998764 35688899999999999999999999999997654431 2566678888899999
2276
2277
2278 Q sp|Q9BYF1|ACE2 239 HLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQ--KPNIDVTDAMVDQAWDAQRIFKEAEKFFV 316 (805)
2279 Q Consensus 239 hlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgq--kpnidvtdamvdqawdaqrifkeaekffv 316 (805)
2280 .+|+|++.+.... |.-+-..|...| |+.+ ++.+++.++. ..+++....++.
2281 T Consensus 294 ~~~~~~~~~~~~~----------------g~~~l~~wD~~~----~~~~~~~~~~~~~~~~-------~~v~~~l~~~~~ 346 (618)
2282 T 3CE2_A 294 LITKYFSIKQRCL----------------NLKDFHFYDVYA----PLSQSKEKKYTFQEAV-------DLIYTSLSPLGT 346 (618)
2283 T ss_dssp HHHHHHHHHHHHH----------------TCSSCBGGGTTC----CSCC--CCCCCHHHHH-------HHHHHHTGGGHH
2284 T ss_pred HHHHHHHHHHHHc----------------CCCCcchhhhcC----CCCcccCCccCHHHHH-------HHHHHHhhhcCH
2285 Confidence 9999999876531 222444554444 3332 3455554431 122222222221
2286
2287
2288 Q sp|Q9BYF1|ACE2 317 SVGLPNMTQGFWENSM---LTDPGNVQKAVCHPTAWDLGKGDFRILMCTKVTMDDFLTAHHEMGHIQYDMAYA-AQPFLL 392 (805)
2289 Q Consensus 317 svglpnmtqgfwensm---ltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghiqydmaya-aqpfll 392 (805)
2290 .++- .+...|+.+.. ...||....+.|++.. .++.+|+||...+++|+.|.+||+||..+.+.+. .+|+..
2291 T Consensus 347 ~~~~-~~~~~~~~~~~iD~~~r~~K~~ga~~~~~~----~~~~~I~~n~~~~~~~~~tl~HElGHa~h~~~~~~~~~~~~ 421 (618)
2292 T 3CE2_A 347 EYID-TLKQGLTTQGWVDKYENLNKRSGAYSSGCY----DSHPYVLLNYTGTLYDVSVIAHEGGHSMHSYFSRKHQPFHD 421 (618)
2293 T ss_dssp HHHH-HHHHHHHTSCCEECSCCTTCCCSCEEECCT----TSCCEEECCCCSSHHHHHHHHHHHHHHHHHHHHHHHSCGGG
2294 T ss_pred HHHH-HHHHHHhhcCceecccCCCCCCCccccCCC----CCCcEEEEecCCCchHHHHHHHHHHHHHHHHHHHhcCchhh
2295 Confidence 1110 01112322222 2234555667887632 2578999999999999999999999999998776 478876
2296
2297
2298 Q sp|Q9BYF1|ACE2 393 RNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQEDNETEINFLLKQALT-IVGTLPFTYMLEKWRWMVF----KG- 466 (805)
2299 Q Consensus 393 rnganegfheavgeimslsaatpkhlksigllspdfqedneteinfllkqalt-ivgtlpftymlekwrwmvf----kg- 466 (805)
2300 +. ...+|+|+++..|.+-...+. ++ +.. +.+..++ ++.+.+. ++.+++...+...|..-++ .|
2301 T Consensus 422 ~~-~~~~~~E~~S~~~E~l~~~~~-~~-------~~~-~~~~~~~-~l~~~l~~~~~~~~~~~~~~~fe~~l~~~~~~~~ 490 (618)
2302 T 3CE2_A 422 AQ-YPIFLAEIASTLNEMLLMDSM-LK-------ESD-SKEEKIT-ILTRCLDTIFSTLFRQVLFASFEYDIHHAAEHGV 490 (618)
2303 T ss_dssp CS-CCGGGTTHHHHHHHHHHHHHH-HH-------HCC-CHHHHHH-HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHTTC
2304 T ss_pred cC-CCHHHHHHHHHHHHHHhHHHH-Hh-------hCC-CHHHHHH-HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCC
2305 Confidence 64 456899999888876655442 11 111 1122344 4444444 4446666655555555555 45
2306
2307
2308 Q sp|Q9BYF1|ACE2 467 EIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHVSNDYSFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISN 546 (805)
2309 Q Consensus 467 eipkdqwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisn 546 (805)
2310 +++.+++.+.||++.++..|+..|.+ ++..+++++..|+-..|-...|..-.+..+++.+.+|. +
2311 T Consensus 491 ~l~~~~l~~~~~~~~~~~~g~~~~~~-~~~~~~w~~~~h~~~~~Y~y~y~~~~~~a~~l~~~~~~--------------~ 555 (618)
2312 T 3CE2_A 491 PLTEEYLSSTYKNLQNEFYGEIITFD-VLSNIEWARIPHFYYNFYVYQYATGIIAALCFLEKILN--------------N 555 (618)
2313 T ss_dssp CCCHHHHHHHHHHHHHHHHTTTCBCC-TTGGGGGGGSCGGGCSSCTHHHHHHHHHHHHHHHHHHT--------------T
2314 T ss_pred CCCHHHHHHHHHHHHHHHhCCCCCCc-cccccHhhccchhhcchhcHHHHHHHHHHHHHHHHHHh--------------C
2315 Confidence 67778999999999999999877665 35566777777764222222222223444555444432 3
2316
2317
2318 Q sp|Q9BYF1|ACE2 547 STEAGQKLFNMLRLGKSEPWTLALENVVGAKNMNVRPLLNYFEPLFTWLKDQNKN 601 (805)
2319 Q Consensus 547 steagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnkn 601 (805)
2320 ..++|.++.++|+.|.+.||.-.++. .|.......++..+|.|+..||+..++.
2321 T Consensus 556 ~~~~~~~~~~~L~~G~s~~~~el~~~-~g~~~~~~~~~~~~~~~l~~~l~~~~~~ 609 (618)
2322 T 3CE2_A 556 EDNALNSYLNFLKSGGSDFPLEILKK-SGLDMGTVEPIQKAFCFIEKKIQELSSL 609 (618)
2323 T ss_dssp CTTHHHHHHHHHTTTTSSCHHHHHHH-TTCCTTSSHHHHHHHHHHHHHHHHHHTT
2324 T ss_pred CchHHHHHHHHHHccCCCCHHHHHHH-cCCCCCCCHHHHHHHHHHHHHHHHHHHH
2325 Confidence 46789999999999999999999984 9999888999999999999999988764
2326
2327
2328 No 27
2329 >2O3E_A Neurolysin (E.C.3.4.24.16); thermolysin-like domain, substrate-binding channel, HYDROLASE; 2.2A {Rattus norvegicus}
2330 Probab=99.90 E-value=9.4e-29 Score=246.41 Aligned_cols=515 Identities=14% Similarity=0.179 Sum_probs=346.7 Template_Neff=9.500
2331
2332 Q sp|Q9BYF1|ACE2 31 KFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMY-------------PLQEIQNLTVKLQL 97 (805)
2333 Q Consensus 31 kfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmy-------------plqeiqnltvklql 97 (805)
2334 .+......+-...+.++|-+.++.+++..+..+.+..+++++..+..+-...| .+.+.+...++..+
2335 T Consensus 68 ~ld~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~ly~~l~~~~~~~~~~~ld~e~~~~l~~~~ 147 (678)
2336 T 2O3E_A 68 VLADIEVTYIVERTMLDFPQHVSSDREVRAASTEADKKLSRFDIEMSMREDVFQRIVHLQETCDLEKIKPEARRYLEKSI 147 (678)
2337 T ss_dssp HHHHHHHHHHHHHHHHHSHHHHCSCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHHHHCCTTSSCHHHHHHHHHHH
2338 T ss_pred HHHHhhhhhHHHHHHHHHHHHhCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHHhcccHhhCCHHHHHHHHHHH
2339 Confidence 33333333556677888999999999999999999999999988875544444 35555666778888
2340
2341
2342 Q sp|Q9BYF1|ACE2 98 QALQQNGSSVLSEDKSKRLNTI---LNTMSTIYSTGKVCNPD-------------------------NPQECLLL-EPGL 148 (805)
2343 Q Consensus 98 qalqqngssvlsedkskrlnti---lntmstiystgkvcnpd-------------------------npqeclll-epgl 148 (805)
2344 +.++++|.. |++++.+++..+ +..++..|+....|... .+ .++.+ .|.+
2345 T Consensus 148 ~~~~~~G~~-L~~~~~~~~~~l~~~i~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~g-~~~~l~~~~~ 225 (678)
2346 T 2O3E_A 148 KMGKRNGLH-LSEHIRNEIKSMKKRMSELCIDFNKNLNEDDTSLVFSKAELGALPDDFIDSLEKTDEDK-YKVTLKYPHY 225 (678)
2347 T ss_dssp HHHHHTTTT-SCHHHHHHTHHHHHHHHHHHHHHHHHHHHCCCEEEEETTTTTTCCHHHHHTSCBCSSSE-EEEESSHHHH
2348 T ss_pred HHHHHcCCC-CCHHHHHHHHHHHHHHHHHHHHHHHhcCCCCcceeCCHHHHcCCCHHHHHHHhcCCCCC-cEEEcCCccH
2349 Confidence 899999975 777666666544 44555556666665421 12 23444 5678
2350
2351
2352 Q sp|Q9BYF1|ACE2 149 NEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEH 228 (805)
2353 Q Consensus 149 neimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedveh 228 (805)
2354 ..+|+++-|...|..+|+.|....++..++++++.+.+++++|+...|++|.+||..++.+ ++..++.+-.+.
2355 T Consensus 226 ~~il~~~~d~~~R~~~~~a~~~~~~~~~~~~l~~ll~lr~~~A~~lGy~s~~~~~l~~~~~-------~s~~~v~~~l~~ 298 (678)
2356 T 2O3E_A 226 FPVMKKCCVPETRRKMEMAFHTRCKQENTAILQQLLPLRAQVAKLLGYNTHADFVLELNTA-------KSTSRVAAFLDD 298 (678)
2357 T ss_dssp HHHHHHCCCHHHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSTT-------CSHHHHHHHHHH
2358 T ss_pred HHHHHhCCCHHHHHHHHHHhhcCCchhHHHHHHHHHHHHHHHHHHhCCCCHHHHHhccCCC-------CCHHHHHHHHHH
2359 Confidence 8999999999999999999998777788999999999999999999999999999876643 233445555666
2360
2361
2362 Q sp|Q9BYF1|ACE2 229 TFEEIKPLYEHLHAYVRAKLMNAYPSY-ISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRI 307 (805)
2363 Q Consensus 229 tfeeikplyehlhayvraklmnaypsy-ispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqri 307 (805)
2364 ..+.++|++++++++++.......+.+ .++.+.+ ..|...|-...+. +...+++++.+.+-+....+
2365 T Consensus 299 l~~~~~p~~~~~~~~l~~~~~~~~~~~g~~~~~~l----------~~wD~~~~~~~~~--~~~~~~~~~~~~~yf~~~~v 366 (678)
2366 T 2O3E_A 299 LSQKLKPLGEAEREFILSLKKKECEERGFEYDGKI----------NAWDLHYYMTQTE--ELKYSVDQESLKEYFPIEVV 366 (678)
2367 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCSSC----------CHHHHHHHHHHHH--HHHTCCCHHHHGGGCBHHHH
2368 T ss_pred HHHHhHHHHHHHHHHHHHHHHHHhHHcCCCcCCCC----------CcccHHHHHHHHH--HhcCCCCHHHHHhhCCHHHH
2369 Confidence 778899999999999987443322211 1111122 3455555554433 22455656666655555444
2370
2371
2372 Q sp|Q9BYF1|ACE2 308 ----FKEAEKFFVSVGLPNM-TQGFWENSMLT---------------------DPGNVQKAVCHPTAWDL--GKG----D 355 (805)
2373 Q Consensus 308 ----fkeaekffvsvglpnm-tqgfwensmlt---------------------dpgnvqkavchptawdl--gkg----d 355 (805)
2374 ++-++++| .+++... ...+|..+... .||.-..+.|.+...+. ..| .
2375 T Consensus 367 ~~~l~~~~~~~f-g~~~~~~~~~~~W~~~v~~~~v~~~~~~~~~g~~ylD~~~r~~K~~~~~~~~~~~~~~~~~g~~~~p 445 (678)
2376 T 2O3E_A 367 TEGLLSIYQELL-GLSFEQVPDAHVWNKSVSLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFGLQPGCLLPDGSRMMS 445 (678)
2377 T ss_dssp HHHHHHHHHHHH-TEEEEECTTCCCSSTTCEEEEEEETTTCCEEEEEEEECSCCTTSCCSCEEEEEECCBBCTTSCBCCE
2378 T ss_pred HHHHHHHHHHHh-CCEEEECCCCCCccCCCeEEEEEECCCCcEEEEEEEECCCCCCCCCCcceeeecCCccCCCCCeeCe
2379 Confidence 34444444 4444332 23457665541 23332233343322211 111 3
2380
2381
2382 Q sp|Q9BYF1|ACE2 356 FRILMCTKV----------TMDDFLTAHHEMGHIQYDMAYAA-QPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLL 424 (805)
2383 Q Consensus 356 frilmctkv----------tmddfltahhemghiqydmayaa-qpfllrnganegfheavgeimslsaatpkhlksigll 424 (805)
2384 +++++|... +.+|+.|.+||+||..+.+.... +|.+...+...+|+|+.+.+|...+..|.+|+.++..
2385 T Consensus 446 ~~~i~~n~~~~~~~~~~ll~~~~~~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~l~E~~~~~~~~L~~l~~~ 525 (678)
2386 T 2O3E_A 446 VAALVVNFSQPVAGRPSLLRHDEVETYFHEFGHVMHQICAQTDFARFSGTNVERDFVEVPSQMLENWVWDVDSLRKLSKH 525 (678)
2387 T ss_dssp EEEEECCCCCCBTTBCCBCCHHHHHHHHHHHHHHHHHHHCCBSSGGGSTTCSCTTTTTHHHHHHHGGGGCHHHHHHHCCC
2388 T ss_pred EEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhcCCcHHHcCCcccchhhchhHHHhHHhhcCHHHHHHHhcc
2389 Confidence 567877653 89999999999999999877652 3333333467899999999999999999999999876
2390
2391
2392 Q sp|Q9BYF1|ACE2 425 SPDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCD 499 (805)
2393 Q Consensus 425 spdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd 499 (805)
2394 ..+-+.-.+..++.+++ +++.++..+++. .++. .++.+.. . ..-+.||++.++..|+ |++.+ .+.
2395 T Consensus 526 ~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~l~~a-~~d~---~l~~~~~-~-~~~~~~~~~~~~~~g~--~~~~~--~~~ 595 (678)
2396 T 2O3E_A 526 YKDGHPITDELLEKLVASRLVNTGLLTLRQIVLS-KVDQ---SLHTNAT-L-DAASEYAKYCTEILGV--AATPG--TNM 595 (678)
2397 T ss_dssp SSSCCCCCHHHHHHHHHTTTTTHHHHHHHHHHHH-HHHH---HHTTCTT-S-CHHHHHHHHCCCCCSS--CCCTT--CCG
2398 T ss_pred CCCCCCCCHHHHHHHHHhhhhhHHHHHHHHHHHH-HHHH---HHhcCCC-c-cHHHHHHHHHHHHHCC--CCCCC--CCC
2399 Confidence 65544445667888888 788888888776 4454 3455542 2 2357888877777786 43322 456
2400
2401
2402 Q sp|Q9BYF1|ACE2 500 PASLFHVSNDYSF--IRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLFN-MLRLGKSEPWTLALENVVGA 576 (805)
2403 Q Consensus 500 paslfhvsndysf--iryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfn-mlrlgksepwtlalenvvga 576 (805)
2404 +.+..|..++|.+ ..|........++-+++|+. .||+ +.++|+++.+ +|..|.+.||.-.++.+.|.
2405 T Consensus 596 ~~~~~hl~~~y~~~Yy~Yl~s~vla~~i~~~~~~~---~~~~-------~~~~g~~~~~~~l~~G~s~~~~e~l~~~~g~ 665 (678)
2406 T 2O3E_A 596 PATFGHLAGGYDGQYYGYLWSEVFSMDMFHSCFKK---EGIM-------NPEVGMKYRNLILKPGGSLDGMDMLQNFLQR 665 (678)
2407 T ss_dssp GGGCTTSSSSCTTCTTHHHHHHHHHHHHCCCCCCH---HCTT-------CHHHHHHHCCCCCTTGGGSCHHHHHHHHHTS
2408 T ss_pred cccHHHHHccchHHHHHHHHHHHHHHHHHHHHHHh---cCCC-------CHHHHHHHHHHhcccCCCCCHHHHHHHHhCC
2409 Confidence 7888898776644 23333333444444443321 2333 3589999998 99999999999999999995
2410
2411
2412 Q sp|Q9BYF1|ACE2 577 KNMNVRPLLNYF 588 (805)
2413 Q Consensus 577 knmnvrpllnyf 588 (805)
2414 .+++.+++.|+
2415 T Consensus 666 -~~~~~~ll~~~ 676 (678)
2416 T 2O3E_A 666 -EPNQKAFLMSR 676 (678)
2417 T ss_dssp -CCCSHHHHHHH
2418 T ss_pred -CCCHHHHHHHc
2419 Confidence 79999988875
2420
2421
2422 No 28
2423 >5LV0_A Neurolysin, mitochondrial (E.C.3.4.24.16), GLY-VAL-VAL amyloid; PROTEASE, MITOCHONDRIA, HYDROLASE, amyloid-beta; 2.7A {Homo sapiens}
2424 Probab=99.89 E-value=6.2e-28 Score=240.22 Aligned_cols=504 Identities=15% Similarity=0.198 Sum_probs=338.6 Template_Neff=9.600
2425
2426 Q sp|Q9BYF1|ACE2 41 YQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP-------------LQEIQNLTVKLQLQALQQNGSSV 107 (805)
2427 Q Consensus 41 yqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp-------------lqeiqnltvklqlqalqqngssv 107 (805)
2428 .....+.|.++++.+++..+..+.+..++++|..+..+-..+|. +.+-+...++..++.++.+|..
2429 T Consensus 83 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~l~~e~~~~l~~~l~~~~~~G~~- 161 (686)
2430 T 5LV0_A 83 VERTMLDFPQHVSSDKEVRAASTEADKRLSRFDIEMSMRGDIFERIVHLQETCDLGKIKPEARRYLEKSIKMGKRNGLH- 161 (686)
2431 T ss_dssp HHHHHHHSHHHHCSCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHHHHHHSCTTTSCHHHHHHHHHHHHHHHHTTTT-
2432 T ss_pred hHHHHhhhHHhhCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHHhccchhcCCHHHHHHHHHHHHHHHHcCCC-
2433 Confidence 44556788899998888888888899999999888765455553 2233334456666777888876
2434
2435
2436 Q sp|Q9BYF1|ACE2 108 LSEDKSKRLNTI---LNTMSTIYSTGKVCNPD-------------------------NPQECLLL-EPGLNEIMANSLDY 158 (805)
2437 Q Consensus 108 lsedkskrlnti---lntmstiystgkvcnpd-------------------------npqeclll-epglneimansldy 158 (805)
2438 |++++.+++..+ +..+++.|+....|... ++ .++-+ .|.+..+|+++-|.
2439 T Consensus 162 L~~~~~~~~~~l~~~~~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~~-~~~~l~~~~~~~~l~~~~d~ 240 (686)
2440 T 5LV0_A 162 LPEQVQNEIKSMKKRMSELCIDFNKNLNEDDTFLVFSKAELGALPDDFIDSLEKTDDDK-YKITLKYPHYFPVMKKCCIP 240 (686)
2441 T ss_dssp SCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECTTTTTTCCHHHHHHSCBCTTSC-EEEESSHHHHHHHHHHCCCH
2442 T ss_pred CCHHHHHHHHHHHHHHHHHHHHHHHccCCCCceeeCCHHHHcCCCHHHHHHHhccCCCC-eEEEcCCccHHHHHHhCCCH
2443 Confidence 455555666665 66667777776665421 11 23333 46788899999999
2444
2445
2446 Q sp|Q9BYF1|ACE2 159 NERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVEHTFEEIKPLYE 238 (805)
2447 Q Consensus 159 nerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfeeikplye 238 (805)
2448 ..|-.+|+.|....++...+++++.+.+++++|+...|.+|.+||...+.+. +...+.+-++...+.++|+++
2449 T Consensus 241 ~~R~~~~~a~~~~~~~~n~~~l~~ll~lR~~~A~~lG~~s~~~~~l~~~~~~-------~~~~v~~~l~~l~~~~~p~~~ 313 (686)
2450 T 5LV0_A 241 ETRRRMEMAFNTRCKEENTIILQQLLPLRTKVAKLLGYSTHADFVLEMNTAK-------STSRVTAFLDDLSQKLKPLGE 313 (686)
2451 T ss_dssp HHHHHHHHHHTTTTHHHHHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSTTC-------SHHHHHHHHHHHHHHHHHHHH
2452 T ss_pred HHHHHHHHHHhcCCchhHHHHHHHHHHHHHHHHHHhCCCCHHHHHhhccCCC-------CHHHHHHHHHHHHHHhHHHHH
2453 Confidence 9999999999887666888999999999999999999999999998776543 233444445556678899999
2454
2455
2456 Q sp|Q9BYF1|ACE2 239 HLHAYVRAKLMNAYPSYISP-IGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQRIFKEAEKFFVS 317 (805)
2457 Q Consensus 239 hlhayvraklmnaypsyisp-igclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvs 317 (805)
2458 .+++++++......+.+-.+ .+.+ ..|...|-+.... +..++++++.+.+.+....+++.+..++-+
2459 T Consensus 314 ~~~~~l~~~~~~~~~~~g~~~~~~l----------~~wD~~~~~~~~~--~~~~~~~~~~~~~yf~~~~v~~~~~~~~~~ 381 (686)
2460 T 5LV0_A 314 AEREFILNLKKKECKDRGFEYDGKI----------NAWDLYYYMTQTE--ELKYSIDQEFLKEYFPIEVVTEGLLNTYQE 381 (686)
2461 T ss_dssp HHHHHHHHHHHHHHHHHTCCCCSSC----------BTTTHHHHHHHHH--HHHHCCCHHHHGGGCBHHHHHHHHHHHHHH
2462 T ss_pred HHHHHHHHHHHHHchhCCCCcCCCC----------ChhhHHHHHHHHH--HHhcCCCHHHHHhhCCHHHHHHHHHHHHHH
2463 Confidence 99999976444322111001 1111 2344444443332 235667777777777777777777777666
2464
2465
2466 Q sp|Q9BYF1|ACE2 318 -VGLPNM---TQGFWENSML---------------------TDPGNVQKAVCHPTAWDLGKG-----DFR-----ILMC- 361 (805)
2467 Q Consensus 318 -vglpnm---tqgfwensml---------------------tdpgnvqkavchptawdlgkg-----dfr-----ilmc- 361 (805)
2468 .|+.-. ...+|.++.. ..+|.-..+.|.+ +..+ +.+ +++|
2469 T Consensus 382 lfg~~~~~~~~~~~w~~~v~~~~v~~~~~~~~lg~~~lD~~~r~~K~~~a~~~~----~~~~~~~~~~~~~~p~~~i~~n 457 (686)
2470 T 5LV0_A 382 LLGLSFEQMTDAHVWNKSVTLYTVKDKATGEVLGQFYLDLYPREGKYNHAACFG----LQPGCLLPDGSRMMAVAALVVN 457 (686)
2471 T ss_dssp HHTEEEEEETTCCCSSTTCEEEEEEETTTCCEEEEEEEECSCCTTSCCSCEEEE----EECCCBCTTSSBCCEEEEEECC
2472 T ss_pred HHCcEEEECCCCCccCCCceEEEEEECCCCcEEEEEEEECCCCCCCCCCcceee----eeCCccCCCCCeeCeEEEEEec
2473 Confidence 665433 2335665533 1234333344443 3222 122 4554
2474
2475
2476 Q sp|Q9BYF1|ACE2 362 ---------TKVTMDDFLTAHHEMGHIQYDMAYAA-QPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLSPDFQED 431 (805)
2477 Q Consensus 362 ---------tkvtmddfltahhemghiqydmayaa-qpfllrnganegfheavgeimslsaatpkhlksigllspdfqed 431 (805)
2478 +.++++|+.|.+||+||..+.+.+.. +|.+...+....|+|+.+.+|..-+..|++|+.++....+-+.-
2479 T Consensus 458 ~~~~~~~~~~~l~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~L~~l~~~~~~~~~~ 537 (686)
2480 T 5LV0_A 458 FSQPVAGRPSLLRHDEVRTYFHQFGHVMHQICAQTDFARFSGTNVETDFVEVPSQMLENWVWDVDSLRRLSKHYKDGSPI 537 (686)
2481 T ss_dssp CCCCBTTBCCBCCHHHHHHHHHHHHHHHHHHHCCCSSSTTSTTCSCTTTTTHHHHHHHGGGGCHHHHHHHCCCTTTCCCC
2482 T ss_pred CCCCCCCCCCCCChHHHHHHHHHHHHHHHHHHhcCCcHHHcCCCccchhchHhHHHhHHhhcCHHHHHHHhhhcCCCCCC
2483 Confidence 56699999999999999999987764 56666667889999999999999999999999988665544333
2484
2485
2486 Q sp|Q9BYF1|ACE2 432 NETEINFLLKQ-----ALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETYCDPASLFHV 506 (805)
2487 Q Consensus 432 neteinfllkq-----altivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycdpaslfhv 506 (805)
2488 .+..++.+++. ++.++..+++. +++. .++.+.. ....+.|+++.++..|+ |.+. ....+.+..|.
2489 T Consensus 538 ~~~~~~~l~~~~~~~~~~~~~~~l~~~-~~d~---~l~~~~~--~~~~~~~~~~~~~~~g~--~~~~--~~~~~~~~~hl 607 (686)
2490 T 5LV0_A 538 ADDLLEKLVASRLVNTGLLTLRQIVLS-KVDQ---SLHTNTS--LDAASEYAKYCSEILGV--AATP--GTNMPATFGHL 607 (686)
2491 T ss_dssp CHHHHHHHHHGGGTTHHHHHHHHHHHH-HHHH---HHTTCCS--SCHHHHHHHHCCCCCCS--BCCT--TCCSGGGCGGG
2492 T ss_pred CHHHHHHHHHhhhHhHHHHHHHHHHHH-HHHH---HHhcCCC--ccHHHHHHHHHHHHhCC--CCCC--CCCCccccHHH
2493 Confidence 45667777776 67777777655 5664 3455542 23578899987887785 3322 23567777888
2494
2495
2496 Q sp|Q9BYF1|ACE2 507 SNDYSFIRYYTRTLYQFQFQEALC-QAAKHEGPLHKCDISNSTEAGQKLFN-MLRLGKSEPWTLALENVVGAKNMNVRPL 584 (805)
2497 Q Consensus 507 sndysfiryytrtlyqfqfqealc-qaakhegplhkcdisnsteagqklfn-mlrlgksepwtlalenvvgaknmnvrpl 584 (805)
2498 ..+|.. .||.. ++..-+...+. +..+..||+ +.++|.++.+ +|..|.+.+|.-.++.+.|. .++..++
2499 T Consensus 608 ~~~y~~-~yY~Y-l~s~~~A~~i~~~~f~~~~~~-------~~~~g~~~~~~~L~~G~s~~~~e~l~~~~G~-~~~~~~l 677 (686)
2500 T 5LV0_A 608 AGGYDG-QYYGY-LWSEVFSMDMFYSCFKKEGIM-------NPEVGMKYRNLILKPGGSLDGMDMLHNFLKR-EPNQKAF 677 (686)
2501 T ss_dssp TTTCTT-CTTHH-HHHHHHHHHHCCCCCTTSCTT-------CHHHHHHHCCCCCTTTTSSCHHHHHHHHHSS-CCCSHHH
2502 T ss_pred Hccchh-HHHHH-HHHHHHHHHHHHHHHHhcCCC-------CHHHHHHHHHHhhhcCCCCCHHHHHHHHhCC-CCCHHHH
2503 Confidence 766653 44421 22211111111 112222332 3689999999 99999999999999999994 7999999
2504
2505
2506 Q sp|Q9BYF1|ACE2 585 LNYFE 589 (805)
2507 Q Consensus 585 lnyfe 589 (805)
2508 +.++.
2509 T Consensus 678 l~~~~ 682 (686)
2510 T 5LV0_A 678 LMSRG 682 (686)
2511 T ss_dssp HHHHT
2512 T ss_pred HHHcC
2513 Confidence 88864
2514
2515
2516 No 29
2517 >1S4B_P Thimet oligopeptidase (E.C.3.4.24.15); Zinc metallopeptidase domain, HYDROLASE; 2.0A {Homo sapiens} SCOP: d.92.1.5
2518 Probab=99.88 E-value=1.6e-27 Score=236.83 Aligned_cols=516 Identities=16% Similarity=0.187 Sum_probs=326.3 Template_Neff=9.600
2519
2520 Q sp|Q9BYF1|ACE2 26 KTFLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYPL-------------QEIQNLT 92 (805)
2521 Q Consensus 26 ktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmypl-------------qeiqnlt 92 (805)
2522 +..+..+......+-...+.+.|.++++.+++..+....+-.++++|..+..+-...|.+ .+.+...
2523 T Consensus 47 ~~~i~~~d~~~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~~~~~ld~e~~r~ 126 (674)
2524 T 1S4B_P 47 ESTLKALADVEVTYTVQRNILDFPQHVSPSKDIRTASTEADKKLSEFDVEMSMREDVYQRIVWLQEKVQKDSLRPEAARY 126 (674)
2525 T ss_pred HHhHHHHHHHHHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHcCCHHHHHHHHHHHhCcchhhCCHHHHHH
2526 Confidence 344556666666677888899999999999999999999999999999887666666652 2222333
2527
2528
2529 Q sp|Q9BYF1|ACE2 93 VKLQLQALQQNGSSVLSEDKSKRLNTIL---NTMSTIYSTGKVCNPDN------------------------PQECLLLE 145 (805)
2530 Q Consensus 93 vklqlqalqqngssvlsedkskrlntil---ntmstiystgkvcnpdn------------------------pqecllle 145 (805)
2531 ++..+..++.+|.. |++++.+++..+. ..++..|.....|.... ...++.+.
2532 T Consensus 127 l~~~l~~~~~~G~~-L~~~~~~~~~~l~~~i~~l~~~f~~~~~~~~~~~~~~~~~l~g~p~~~~~~~~~~~~~~~~~~l~ 205 (674)
2533 T 1S4B_P 127 LERLIKLGRRNGLH-LPRETQENIKRIKKKLSLLCIDFNKNLNEDTTFLPFTLQELGGLPEDFLNSLEKMEDGKLKVTLK 205 (674)
2534 T ss_pred HHHHHHHHHHcCCC-CCHHHHHHHHHHHHHHHHHHHHHHHhccccccccEEeHHHHcCCCHHHHHHHHHHHcCCeEEEcC
2535 Confidence 45555666777754 6666656665554 44677777777665321 11234444
2536
2537
2538 Q sp|Q9BYF1|ACE2 146 -PGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIE 224 (805)
2539 Q Consensus 146 -pglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqlie 224 (805)
2540 |.+..+|+++-|...|-.+|+.|+...++...+++++.+.+++++|+...|.+|.+||..++.+. +..++.+
2541 T Consensus 206 ~~~~~~il~~~~d~~~R~~~~~a~~~~~~~~~~~~l~~l~~lR~~~A~~lGy~s~~~~~l~~~~~~-------~~~~v~~ 278 (674)
2542 T 1S4B_P 206 YPHYFPLLKKCHVPETRRKVEEAFNSRCKEENSAILKELVTLRAQKSRLLGFHTHADYVLEMNMAK-------TSQTVAT 278 (674)
2543 T ss_pred CccHHHHHhcCCCHHHHHHHHHHHHccCCcccHHHHHHHHHHHHHHHHHhCCCCHHHHHccccCCC-------CHHHHHH
2544 Confidence 67899999999999999999999987777889999999999999999999999999998765442 2223333
2545
2546
2547 Q sp|Q9BYF1|ACE2 225 DVEHTFEEIKPLYEHLHAYVRAKLM---NAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQA 301 (805)
2548 Q Consensus 225 dvehtfeeikplyehlhayvraklm---naypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqa 301 (805)
2549 -.+...+.++|+|+..+++++.... +.+.. +..+-+ ..|...|-...+... ...+..+.+...
2550 T Consensus 279 ~l~~l~~~~~p~~~~~~~~l~~~~~~~~~~~g~--~~~~~l----------~~wD~~y~~~~~~~~--~~~~~~~~i~~y 344 (674)
2551 T 1S4B_P 279 FLDELAQKLKPLGEQERAVILELKRAECERRGL--PFDGRI----------RAWDMRYYMNQVEET--RYCVDQNLLKEY 344 (674)
2552 T ss_pred HHHHHHHHhHHHHHHHHHHHHHHHHHHHHhcCC--CCCCCC----------ChhcHHHHHHHHHHh--cCCCCHHHHHhh
2553 Confidence 3445567889999999888775322 22210 001111 234444444333211 223333333332
2554
2555
2556 Q sp|Q9BYF1|ACE2 302 WD----AQRIFKEAEKFFVSVGLPN---MTQGFWENSML-----------------TD----PGNVQKAVCHPTAWDL-- 351 (805)
2557 Q Consensus 302 wd----aqrifkeaekffvsvglpn---mtqgfwensml-----------------td----pgnvqkavchptawdl-- 351 (805)
2558 .. ...+++.++++| |+.. ....+|.++.. .| ||.-..+.|.+...+.
2559 T Consensus 345 f~~~~~~~~l~~~~~~~f---g~~~~~~~~~~~W~~~v~~~~v~d~~~~~~lg~~~lD~~~r~~K~~~a~~~~~~~~~~~ 421 (674)
2560 T 1S4B_P 345 FPVQVVTHGLLGIYQELL---GLAFHHEEGASAWHEDVRLYTARDAASGEVVGKFYLDLYPREGKYGHAACFGLQPGCLR 421 (674)
2561 T ss_pred CCHHHHHHHHHHHHHHHh---CCEEEECCCCCcccCCceEEEEEeCCCCcEEEEEEEECCCCCCCCCCcceeeEecCccC
2562 Confidence 21 245666666666 4322 24456777654 22 2222234444332211
2563
2564
2565 Q sp|Q9BYF1|ACE2 352 --GKGD--FRIL----------MCTKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLRNGAN--EGFHEAVGEIMSLSAATP 415 (805)
2566 Q Consensus 352 --gkgd--fril----------mctkvtmddfltahhemghiqydmayaaqpfllrngan--egfheavgeimslsaatp 415 (805)
2567 |+.. ..++ .|+.++.+|+.|.+||+||..+.+.+..++. ...|++ -.|+|+.+.+|...+..|
2568 T Consensus 422 ~~~~~~~p~~~l~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~-~~~g~~~~~d~~E~~S~~~E~~~~~~ 500 (674)
2569 T 1S4B_P 422 QDGSRQIAIAAMVANFTKPTADAPSLLQHDEVETYFHEFGHVMHQLCSQAEFA-MFSGTHVERDFVEAPSQMLENWVWEQ 500 (674)
2570 T ss_pred CCCCeeccEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhCCCch-hhcCCCCCCcccccchHHHHHhhcCH
2571 Confidence 1000 0122 6778889999999999999999998876544 456655 799999999999999999
2572
2573
2574 Q sp|Q9BYF1|ACE2 416 KHLKSIGLLSPDFQEDNETEINFLLKQA-----LTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEP 490 (805)
2575 Q Consensus 416 khlksigllspdfqedneteinfllkqa-----ltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvep 490 (805)
2576 ++|+.++.-..+-+.-.+..++.+++.. +.++..+.+ ..++.+ ++.+. ..++.+.||++..+..|+ |
2577 T Consensus 501 ~~L~~l~~~~~~~~~l~~~~~~~l~~~~~~~~~l~~~~~l~~-~~~d~~---l~~~~--~~~~~~~~~~l~~~~~g~--~ 572 (674)
2578 T 1S4B_P 501 EPLLRMSRHYRTGSAVPRELLEKLIESRQANTGLFNLRQIVL-AKVDQA---LHTQT--DADPAEEYARLCQEILGV--P 572 (674)
2579 T ss_pred HHHHHHhhccCCCCCCCHHHHHHHHHhhcHHHHHHHHHHHHH-HHHHHH---HhcCC--CCcHHHHHHHHHHHHcCC--C
2580 Confidence 9999887543221111233455554322 222222222 222322 23222 256788899999998887 3
2581
2582
2583 Q sp|Q9BYF1|ACE2 491 VPHDETYCDPASLFHVSNDYSF--IRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWT 567 (805)
2584 Q Consensus 491 vphdetycdpaslfhvsndysf--iryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwt 567 (805)
2585 .+.+ ...+.+..|...+|.+ ..|....+..+++-.+.| +..||+ +.++|.++. ++|..|.+.+|.
2586 T Consensus 573 ~~~~--~~~~~~~~h~~~~y~~~yysYl~s~v~A~~i~~~~~---~~~~~~-------~~~~g~~~~~~~L~~G~s~~~~ 640 (674)
2587 T 1S4B_P 573 ATPG--TNMPATFGHLAGGYDAQYYGYLWSEVYSMDMFHTRF---KQEGVL-------NSKVGMDYRSCILRPGGSEDAS 640 (674)
2588 T ss_pred CCCC--CCchhhhHHHHccchHHHHHHHHHHHHHHHHHHHHH---hhhCCC-------CHHHHHHHHHHhcccCCCCCHH
2589 Confidence 3222 3466778888755544 333333333444322222 223443 358899998 899999999999
2590
2591
2592 Q sp|Q9BYF1|ACE2 568 LALENVVGAKNMNVRPLLNYF 588 (805)
2593 Q Consensus 568 lalenvvgaknmnvrpllnyf 588 (805)
2594 -.++++.| .+++..+++.++
2595 T Consensus 641 e~l~~~lG-~~~~~~~~l~~~ 660 (674)
2596 T 1S4B_P 641 AMLRRFLG-RDPKQDAFLLSK 660 (674)
2597 T ss_pred HHHHHHhC-CCCCHHHHHHHc
2598 Confidence 99999988 568888887665
2599
2600
2601 No 30
2602 >5L44_A K-26 dipeptidyl carboxypeptidase; dipeptidyl carboxypeptidase, metalloprotease, K-26 tripeptide; HET: K26, SO4; 1.75A {Astrosporangium hypotensionis K-26}
2603 Probab=99.77 E-value=4.9e-23 Score=205.45 Aligned_cols=512 Identities=16% Similarity=0.122 Sum_probs=318.9 Template_Neff=9.600
2604
2605 Q sp|Q9BYF1|ACE2 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP---------LQEIQNLTVKLQLQ 98 (805)
2606 Q Consensus 28 fldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp---------lqeiqnltvklqlq 98 (805)
2607 ++..+..-...+..-.+++++.+.++.+++..+..+.+..+.+.+..+.......|. +.+-+...++..++
2608 T Consensus 76 ~i~~le~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~l~~e~~~~l~~~l~ 155 (683)
2609 T 5L44_A 76 TVAALERSGQVLTRVSAVFFNQSSSDTNPTVQEIQKQIIPKLTQHGDAIHLNRPLFARIKQISPDGLDAEQAWLLERYVT 155 (683)
2610 T ss_dssp CCCHHHHCCHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHTCCCTTCCHHHHHHHHHHHH
2611 T ss_pred HHHHHHHhhHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHcccCCCHHHHHHHHHHHH
2612 Confidence 344444444555556778888888887888888888888888888766655444443 22223445556677
2613
2614
2615 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSED--KSKRLNTILNTMSTIYS----TGK----VCN---------PDN--------------PQ-ECLLL 144 (805)
2616 Q Consensus 99 alqqngssvlsed--kskrlntilntmstiys----tgk----vcn---------pdn--------------pq-eclll 144 (805)
2617 .+.++|...++++ +-..++..+..++..|+ +.+ +|- |.. +. .++-+
2618 T Consensus 156 ~~~~~G~~l~~~~~e~~~~l~~~~~~l~~~f~~n~~~~~~~~~~~~~~~~~l~glp~~~~~~~~~~~~~~~~~G~~~i~l 235 (683)
2619 T 5L44_A 156 DFVRAGAELGAGDQERLKALNEELSTLSTRFEQNLLAHTNASAVIVDDVAQLDGLSDDSVKAAAETAKSRGLPGKYVIPL 235 (683)
2620 T ss_dssp HHHHTTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCEEESCGGGGTTSCHHHHHHHHHHHHHTTCTTSEEECC
2621 T ss_pred HHHHhcccCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccceecCCHHHHCCCCHHHHHHHHHHHHHcCCCCCeEEec
2622 Confidence 7888888877765 34445666777778887 332 332 110 11 23444
2623
2624
2625 Q sp|Q9BYF1|ACE2 145 E-PGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLI 223 (805)
2626 Q Consensus 145 e-pglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqli 223 (805)
2627 . |....+|.++-|...|-.+|++|.....+...+++++.+-+++++|+...|++|.+||-.++.+...
2628 T Consensus 236 ~~~~~~~il~~~~d~~~Rk~~~~a~~~~~~~~n~~~l~~lv~~R~~~A~~lGy~s~a~~~l~~~~~~~~----------- 304 (683)
2629 T 5L44_A 236 VLPTGQPGLAELTDRALRERIHRASIQRGVPDNEELIVRIATLRAERAKLLGYPTHAAYVVADQTAPTT----------- 304 (683)
2630 T ss_dssp CSSSSCGGGGTCCCHHHHHHHHHHHHTTTTTTTHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSSSCCH-----------
2631 T ss_pred CCCchHHHHHhCCCHHHHHHHHHHHHhcCCcchHHHHHHHHHHHHHHHHHhCCCCHHHHHcCCCCCCCH-----------
2632 Confidence 4 6788899999999999999999997655678899999999999999999999999999877665421
2633
2634
2635 Q sp|Q9BYF1|ACE2 224 EDVEHTFEE-IKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAW 302 (805)
2636 Q Consensus 224 edvehtfee-ikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqaw 302 (805)
2637 ++|.....+ +++++..+|++++.+... + |+ --..|.-.|-....... .+.+..+.+..-.
2638 T Consensus 305 ~~v~~~L~~l~~~~~p~~~~~~~~l~~~-~---------------~~-~l~~wD~~y~~~~~~~~--~~~~~~~~~~~yf 365 (683)
2639 T 5L44_A 305 EAVTEMLGKLTPPAVANAHREADELREQ-A---------------GH-DLEPWDWSFYAEKVLKE--RYAIDGRQMRPYF 365 (683)
2640 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHH-H---------------SS-CCCGGGHHHHHHHHHHH--HHCCCHHHHGGGC
2641 T ss_pred HHHHHHHHHhhHHhHHHHHHHHHHHHHH-c---------------CC-CCCccCHHHHHHHHHHH--hhCCChhHhHhhc
2642 Confidence 223222222 346666778887754321 1 11 01223332322211111 1111111111111
2643
2644
2645 Q sp|Q9BYF1|ACE2 303 DAQ-----RIFKEAEKFF--------------------VSVGL-PNMTQGFWENSMLTDPGNVQKAVCHPTAWD--LGKG 354 (805)
2646 Q Consensus 303 daq-----rifkeaekff--------------------vsvgl-pnmtqgfwensmltdpgnvqkavchptawd--lgkg 354 (805)
2647 ... .+|.-++++| .-.+- ......+|-. ....+|....+.|++..-. ....
2648 T Consensus 366 ~~~~v~~~~l~~~~~~lfg~~~~~~~~~~~w~~~v~~~~v~~~~~~~lg~~~lD-~~~r~~K~~~~~~~~~~~~~~~~~~ 444 (683)
2649 T 5L44_A 366 ELDRVLRDGVFHAATLLYGITFTERPDLVGYHPDVRVFEVFNEDGSQLGLFLGD-YYARPSKRGGAWMNSLVKQSTLEGT 444 (683)
2650 T ss_dssp BHHHHCCCCCCHHHHHHHCCEEEECTTSCCSSTTCEEEEEECTTSCEEEEEEEE-EECCTTSCSSCEEEEEECCBTTTTB
2651 T ss_pred CHHHHHHHHHHHHHHHHhCCEEEECCCCCCccCCeEEEEEEcCCCCEEEEEEEe-ccCCCCCCCCccccccccccccCCC
2652 Confidence 111 1222222221 00000 0111113322 1223344444566653210 0134
2653
2654
2655 Q sp|Q9BYF1|ACE2 355 DFRILMCTK-----------VTMDDFLTAHHEMGHIQYDMAYA-AQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIG 422 (805)
2656 Q Consensus 355 dfrilmctk-----------vtmddfltahhemghiqydmaya-aqpfllrnganegfheavgeimslsaatpkhlksig 422 (805)
2657 ...|.+|.. .+.+|+.|.+||+||..+.+... .+|.+.+.+....|.|+.+.+|.+-+..|.+|++++
2658 T Consensus 445 ~p~v~l~~~~~~~~~~~~~l~~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~L~~~~ 524 (683)
2659 T 5L44_A 445 RPVVVNNLNIAKPPAGEPTLMTFEEVNTMFHEFGHALHGLFSEVHYPRFSGTAVPRDFVEYPSQVNEMWAVWPSVLANYA 524 (683)
2660 T ss_dssp CCEEEEEEEECCCCTTCCCBCCHHHHHHHHHHHHHHHHHHTCCCSSGGGCTTCSCHHHHHHHHHHHTHHHHCHHHHHHHC
2661 T ss_pred CCEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHcCCCCccccCCCCCchhhccchHHhHhhhcCHHHHHHHh
2662 Confidence 577888887 89999999999999999988765 577777777889999999999999999999999987
2663
2664
2665 Q sp|Q9BYF1|ACE2 423 LLSPDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
2666 Q Consensus 423 llspdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
2667 ....+-+.-.+..++.++. +++.++..+++. .++.+ ++.+..+.+.+..-||+...+. |+.-|... . .
2668 T Consensus 525 ~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~l~~a-~~D~~---lh~~~~~~~~~~~~~~~~~~~~-g~~~~~~~-~-~ 597 (683)
2669 T 5L44_A 525 RHWQTGDPMPKDLLDRMLKSQKYNQGYKTVEYLAAT-LLDWS---WHTFQTPPENALTFEHEALTTA-GVDLKLVP-P-R 597 (683)
2670 T ss_dssp BCTTTCCBCCHHHHHHHHHTTSTTHHHHHHHHHHHH-HHHHH---HTSCSSCCSCHHHHHHHHHHHT-TCCBTTBC-C-S
2671 T ss_pred hccCCCCCCCHHHHHHHHHhhchhHHHHHHHHHHHH-HHHHH---HhcCCCCCccHHHHHHHHHHHh-CCCCCCCC-C-c
2672 Confidence 6643222224455666654 567777777775 66655 3444444466777788866665 76544321 1 2
2673
2674
2675 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSN-DYS--FIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLALENV 573 (805)
2676 Q Consensus 498 cdpaslfhvsn-dys--firyytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwtlalenv 573 (805)
2677 ..+.+..|+.. +|. +..|....+..++.-+++|++ ||+ +.++|+++. .+|+.|.+.||.-.++..
2678 T Consensus 598 ~~~~~~~hi~~~~y~~~yy~Yl~s~v~a~~i~~~f~~~----~~~-------~~~~g~~~r~~iL~~G~s~~~~e~l~~f 666 (683)
2679 T 5L44_A 598 YRSTYFAHIWSSGYSAGYYSYIWSEVLDADTVDWFHEN----GGL-------LRENGDTFRQKLLSKGGSVDPMTAFQSF 666 (683)
2680 T ss_dssp SCGGGCHHHHTSSCTTCTTHHHHHHHHHHHHHHHHHHT----TSS-------CHHHHHHHCCCCCTCTTSSCHHHHHHHH
2681 T ss_pred ccccccHhHhcCCchHHHHHHHHHHHHHHHHHHHHHHc----CCC-------cHHHHHHHHHHHHHcCCCCCHHHHHHHH
2682 Confidence 23677777654 443 335555555666666665543 444 358899999 999999999999999999
2683
2684
2685 Q sp|Q9BYF1|ACE2 574 VGAKNMNVRPLLNYFE 589 (805)
2686 Q Consensus 574 vgaknmnvrpllnyfe 589 (805)
2687 .|.. .+..+++.|+.
2688 T Consensus 667 ~G~~-~s~~~~l~~~~ 681 (683)
2689 T 5L44_A 667 RGRT-PRIEPLLDRRG 681 (683)
2690 T ss_dssp HSSS-CCSHHHHHHHT
2691 T ss_pred hCCC-CChHHHHHHcC
2692 Confidence 9986 88888888764
2693
2694
2695 No 31
2696 >5L43_B K-26 dipeptidyl carboxypeptidase; dipeptidyl carboxypeptidase, metalloprotease, K-26 tripeptide; HET: SO4; 1.8A {Astrosporangium hypotensionis K-26}
2697 Probab=99.77 E-value=4.9e-23 Score=205.45 Aligned_cols=512 Identities=16% Similarity=0.122 Sum_probs=318.9 Template_Neff=9.600
2698
2699 Q sp|Q9BYF1|ACE2 28 FLDKFNHEAEDLFYQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMYP---------LQEIQNLTVKLQLQ 98 (805)
2700 Q Consensus 28 fldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmyp---------lqeiqnltvklqlq 98 (805)
2701 ++..+..-...+..-.+++++.+.++.+++..+..+.+..+.+.+..+.......|. +.+-+...++..++
2702 T Consensus 76 ~i~~le~~~~~l~~~~~~~~~~~~~~~~~~~r~~~~~~~~~~~~~~~~~~~~~~l~~~l~~~~~~~l~~e~~~~l~~~l~ 155 (683)
2703 T 5L43_B 76 TVAALERSGQVLTRVSAVFFNQSSSDTNPTVQEIQKQIIPKLTQHGDAIHLNRPLFARIKQISPDGLDAEQAWLLERYVT 155 (683)
2704 T ss_dssp CCCHHHHCCHHHHHHHHHHHHHHHHSCCHHHHHHHHHHHHHHHHHHHHHHTCHHHHHHHHTCCSTTCCHHHHHHHHHHHH
2705 T ss_pred HHHHHHHhhHHHHHHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHhcCHHHHHHHHHHcccCCCHHHHHHHHHHHH
2706 Confidence 344444444555556778888888887888888888888888888766655444443 22223445556677
2707
2708
2709 Q sp|Q9BYF1|ACE2 99 ALQQNGSSVLSED--KSKRLNTILNTMSTIYS----TGK----VCN---------PDN--------------PQ-ECLLL 144 (805)
2710 Q Consensus 99 alqqngssvlsed--kskrlntilntmstiys----tgk----vcn---------pdn--------------pq-eclll 144 (805)
2711 .+.++|...++++ +-..++..+..++..|+ +.+ +|- |.. +. .++-+
2712 T Consensus 156 ~~~~~G~~l~~~~~e~~~~l~~~~~~l~~~f~~n~~~~~~~~~~~~~~~~~l~glp~~~~~~~~~~~~~~~~~G~~~i~l 235 (683)
2713 T 5L43_B 156 DFVRAGAELGAGDQERLKALNEELSTLSTRFEQNLLAHTNASAVIVDDVAQLDGLSDDSVKAAAETAKSRGLPGKYVIPL 235 (683)
2714 T ss_dssp HHHHTTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCEEESCGGGGTTSCHHHHHHHHHHHHHTTCTTSEEECC
2715 T ss_pred HHHHhcccCCHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccceecCCHHHHCCCCHHHHHHHHHHHHHcCCCCCeEEec
2716 Confidence 7888888877765 34445666777778887 332 332 110 11 23444
2717
2718
2719 Q sp|Q9BYF1|ACE2 145 E-PGLNEIMANSLDYNERLWAWESWRSEVGKQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLI 223 (805)
2720 Q Consensus 145 e-pglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqli 223 (805)
2721 . |....+|.++-|...|-.+|++|.....+...+++++.+-+++++|+...|++|.+||-.++.+...
2722 T Consensus 236 ~~~~~~~il~~~~d~~~Rk~~~~a~~~~~~~~n~~~l~~lv~~R~~~A~~lGy~s~a~~~l~~~~~~~~----------- 304 (683)
2723 T 5L43_B 236 VLPTGQPGLAELTDRALRERIHRASIQRGVPDNEELIVRIATLRAERAKLLGYPTHAAYVVADQTAPTT----------- 304 (683)
2724 T ss_dssp CSSSSCGGGGTCCCHHHHHHHHHHHHTTTTTTTHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSSSCCH-----------
2725 T ss_pred CCCchHHHHHhCCCHHHHHHHHHHHHhcCCcchHHHHHHHHHHHHHHHHHhCCCCHHHHHcCCCCCCCH-----------
2726 Confidence 4 6788899999999999999999997655678899999999999999999999999999877665421
2727
2728
2729 Q sp|Q9BYF1|ACE2 224 EDVEHTFEE-IKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAW 302 (805)
2730 Q Consensus 224 edvehtfee-ikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqaw 302 (805)
2731 ++|.....+ +++++..+|++++.+... + |+ --..|.-.|-....... .+.+..+.+..-.
2732 T Consensus 305 ~~v~~~L~~l~~~~~p~~~~~~~~l~~~-~---------------~~-~l~~wD~~y~~~~~~~~--~~~~~~~~~~~yf 365 (683)
2733 T 5L43_B 305 EAVTEMLGKLTPPAVANAHREADELREQ-A---------------GH-DLEPWDWSFYAEKVLKE--RYAIDGRQMRPYF 365 (683)
2734 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHH-H---------------TS-CCCGGGHHHHHHHHHHH--HHCCCHHHHGGGC
2735 T ss_pred HHHHHHHHHhhHHhHHHHHHHHHHHHHH-c---------------CC-CCCccCHHHHHHHHHHH--hhCCChhHhHhhc
2736 Confidence 223222222 346666778887754321 1 11 01223332322211111 1111111111111
2737
2738
2739 Q sp|Q9BYF1|ACE2 303 DAQ-----RIFKEAEKFF--------------------VSVGL-PNMTQGFWENSMLTDPGNVQKAVCHPTAWD--LGKG 354 (805)
2740 Q Consensus 303 daq-----rifkeaekff--------------------vsvgl-pnmtqgfwensmltdpgnvqkavchptawd--lgkg 354 (805)
2741 ... .+|.-++++| .-.+- ......+|-. ....+|....+.|++..-. ....
2742 T Consensus 366 ~~~~v~~~~l~~~~~~lfg~~~~~~~~~~~w~~~v~~~~v~~~~~~~lg~~~lD-~~~r~~K~~~~~~~~~~~~~~~~~~ 444 (683)
2743 T 5L43_B 366 ELDRVLRDGVFHAATLLYGITFTERPDLVGYHPDVRVFEVFNEDGSQLGLFLGD-YYARPSKRGGAWMNSLVKQSTLEGT 444 (683)
2744 T ss_dssp BHHHHCCCCCHHHHHHHHCCEEEECTTSCCSSTTCEEEEEECTTSCEEEEEEEE-EECCTTSCSSCEEEEEECCBTTTTB
2745 T ss_pred CHHHHHHHHHHHHHHHHhCCEEEECCCCCCccCCeEEEEEEcCCCCEEEEEEEe-ccCCCCCCCCccccccccccccCCC
2746 Confidence 111 1222222221 00000 0111113322 1223344444566653210 0134
2747
2748
2749 Q sp|Q9BYF1|ACE2 355 DFRILMCTK-----------VTMDDFLTAHHEMGHIQYDMAYA-AQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIG 422 (805)
2750 Q Consensus 355 dfrilmctk-----------vtmddfltahhemghiqydmaya-aqpfllrnganegfheavgeimslsaatpkhlksig 422 (805)
2751 ...|.+|.. .+.+|+.|.+||+||..+.+... .+|.+.+.+....|.|+.+.+|.+-+..|.+|++++
2752 T Consensus 445 ~p~v~l~~~~~~~~~~~~~l~~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~L~~~~ 524 (683)
2753 T 5L43_B 445 RPVVVNNLNIAKPPAGEPTLMTFEEVNTMFHEFGHALHGLFSEVHYPRFSGTAVPRDFVEYPSQVNEMWAVWPSVLANYA 524 (683)
2754 T ss_dssp CCEEEEEEEECCCCTTCCCBCCHHHHHHHHHHHHHHHHHHTCCCSSGGGCTTCSCHHHHHHHHHHHTHHHHCHHHHHHHC
2755 T ss_pred CCEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHcCCCCccccCCCCCchhhccchHHhHhhhcCHHHHHHHh
2756 Confidence 577888887 89999999999999999988765 577777777889999999999999999999999987
2757
2758
2759 Q sp|Q9BYF1|ACE2 423 LLSPDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVGVVEPVPHDETY 497 (805)
2760 Q Consensus 423 llspdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdety 497 (805)
2761 ....+-+.-.+..++.++. +++.++..+++. .++.+ ++.+..+.+.+..-||+...+. |+.-|... . .
2762 T Consensus 525 ~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~~l~~a-~~D~~---lh~~~~~~~~~~~~~~~~~~~~-g~~~~~~~-~-~ 597 (683)
2763 T 5L43_B 525 RHWQTGDPMPKDLLDRMLKSQKYNQGYKTVEYLAAT-LLDWS---WHTFQTPPENALTFEHEALTTA-GVDLKLVP-P-R 597 (683)
2764 T ss_dssp BCTTTCCBCCHHHHHHHHHTTSTTHHHHHHHHHHHH-HHHHH---HTTCSSCCSCHHHHHHHHHHHT-TCCBTTBC-C-S
2765 T ss_pred hccCCCCCCCHHHHHHHHHhhchhHHHHHHHHHHHH-HHHHH---HhcCCCCCccHHHHHHHHHHHh-CCCCCCCC-C-c
2766 Confidence 6643222224455666654 567777777775 66655 3444444466777788866665 76544321 1 2
2767
2768
2769 Q sp|Q9BYF1|ACE2 498 CDPASLFHVSN-DYS--FIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLALENV 573 (805)
2770 Q Consensus 498 cdpaslfhvsn-dys--firyytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwtlalenv 573 (805)
2771 ..+.+..|+.. +|. +..|....+..++.-+++|++ ||+ +.++|+++. .+|+.|.+.||.-.++..
2772 T Consensus 598 ~~~~~~~hi~~~~y~~~yy~Yl~s~v~a~~i~~~f~~~----~~~-------~~~~g~~~r~~iL~~G~s~~~~e~l~~f 666 (683)
2773 T 5L43_B 598 YRSTYFAHIWSSGYSAGYYSYIWSEVLDADTVDWFHEN----GGL-------LRENGDTFRQKLLSKGGSVDPMTAFQSF 666 (683)
2774 T ss_dssp SCGGGCHHHHTSSCTTCTTHHHHHHHHHHHHHHHHHHT----TSS-------CHHHHHHHCCCCCTCTTSSCHHHHHHHH
2775 T ss_pred ccccccHhHhcCCchHHHHHHHHHHHHHHHHHHHHHHc----CCC-------cHHHHHHHHHHHHHcCCCCCHHHHHHHH
2776 Confidence 23677777654 443 335555555666666665543 444 358899999 999999999999999999
2777
2778
2779 Q sp|Q9BYF1|ACE2 574 VGAKNMNVRPLLNYFE 589 (805)
2780 Q Consensus 574 vgaknmnvrpllnyfe 589 (805)
2781 .|.. .+..+++.|+.
2782 T Consensus 667 ~G~~-~s~~~~l~~~~ 681 (683)
2783 T 5L43_B 667 RGRT-PRIEPLLDRRG 681 (683)
2784 T ss_dssp HSSS-CCSHHHHHHHT
2785 T ss_pred hCCC-CChHHHHHHcC
2786 Confidence 9986 88888888764
2787
2788
2789 No 32
2790 >1Y79_1 Peptidyl-Dipeptidase Dcp (E.C.3.4.15.5); hinge bending peptidyl dipeptidase; HET: TRP; 2.0A {Escherichia coli}
2791 Probab=99.44 E-value=4.5e-17 Score=163.19 Aligned_cols=501 Identities=14% Similarity=0.139 Sum_probs=281.7 Template_Neff=9.600
2792
2793 Q sp|Q9BYF1|ACE2 41 YQSSLASWNYNTNITEENVQNMNNAGDKWSAFLKEQSTLAQMY-------------PLQEIQNLTVKLQLQALQQNGSSV 107 (805)
2794 Q Consensus 41 yqsslaswnyntniteenvqnmnnagdkwsaflkeqstlaqmy-------------plqeiqnltvklqlqalqqngssv 107 (805)
2795 .-.+.+++-+.++.+++.-..-..+..+.+++..+..+=..+| .+.+-+...++..++....+|...
2796 T Consensus 70 ~~~~~~~~l~~~~~~~e~r~a~~~~~~~~~~~~~~~~~~~~ly~~l~~~~~~~~~~~l~~e~~r~l~~~l~~~~~~G~~L 149 (680)
2797 T 1Y79_1 70 RVTSVFFAMTAAHTNDELQRLDEQFSAELAELANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKL 149 (680)
2798 T ss_pred HHHHHHHHHHhcCCCHHHHHHHHHHHHHHHHHHHHHccCHHHHHHHHHHHcCCCccCCCHHHHHHHHHHHHHHHHcCCCC
2799 Confidence 3455666667777555554445555555665544432111111 122223334555666677788765
2800
2801
2802 Q sp|Q9BYF1|ACE2 108 LSEDKSKRLNTILNT---MSTIYSTGKVC---------N--------PD----------------NPQECLLLEPGLNEI 151 (805)
2803 Q Consensus 108 lsedkskrlntilnt---mstiystgkvc---------n--------pd----------------npqeclllepglnei 151 (805)
2804 .++ +.+|+..+... +++.|+..-.. . |+ .+...-+-.|.+..+
2805 T Consensus 150 ~~~-~~~~l~~l~~~i~~l~~~f~~n~~~~~~~~~~~~~~~~~L~g~p~~~l~~~~~~a~~~~~~~~~~i~l~~~~~~~~ 228 (680)
2806 T 1Y79_1 150 AQA-DKAKLKVLNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWLIPLLNTTQQPA 228 (680)
2807 T ss_pred CHH-HHHHHHHHHHHHHHHHHHHHHhcccccccccccCCCHHHHcCCCHHHHHHHHHHHHHcCCCCCeEeeCCCccHHHH
2808 Confidence 444 44666655443 22223211110 0 00 111122223567888
2809
2810
2811 Q sp|Q9BYF1|ACE2 152 MANSLDYNERLWAWESWRSEVG----KQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRGQLIEDVE 227 (805)
2812 Q Consensus 152 mansldynerlwaweswrsevg----kqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedve 227 (805)
2813 |+++-|...|--+|..|.+... ....+++.+.+.+++++|+...|++|.+|+-.+.. ..+..++.+-..
2814 T Consensus 229 l~~~~d~~~R~~~~~a~~~~~~~~~~~~~~~~l~~lv~~R~~~A~llGy~s~~~~~l~~~m-------~~~~~~v~~~L~ 301 (680)
2815 T 1Y79_1 229 LAEMRDRATREKLFIAGWTRAEKNDANDTRAIIQRLVEIRAQQATLLGFPHYAAWKIADQM-------AKTPEAALNFMR 301 (680)
2816 T ss_pred HHhCCCHHHHHHHHHHHHhccccCCccccHHHHHHHHHHHHHHHHHhCCCCHHHHHhcccC-------CCCHHHHHHHHH
2817 Confidence 9999999999999999975543 46789999999999999999999999999864431 223334444455
2818
2819
2820 Q sp|Q9BYF1|ACE2 228 HTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQKPNIDVTDAMVDQAWDAQR- 306 (805)
2821 Q Consensus 228 htfeeikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqr- 306 (805)
2822 ...+.++|++++.++.+++.....+ |+--...|...|-...+-. ...+++++.+.+-....+
2823 T Consensus 302 ~l~~~~~p~~~~e~~~l~~~~~~~~---------------g~~~l~~wD~~y~~~~~~~--~~~~~~~~~~~~yf~~~~v 364 (680)
2824 T 1Y79_1 302 EIVPAARQRASDELASIQAVIDKQQ---------------GGFSAQPWDWAFYAEQVRR--EKFDLDEAQLKPYFELNTV 364 (680)
2825 T ss_pred HHHHHhHHHHHHHHHHHHHHHHHhc---------------CCCCCCcccHHHHHHhHHh--hccCCCHHHHHhhCCHHHH
2826 Confidence 5567888999988888887554322 1111233433333222211 223343444433333332
2827
2828
2829 Q sp|Q9BYF1|ACE2 307 ----IFKEAEKFFVSVGLPN---MTQGFWENSM----------------LTDP----GNVQKAVCHPTAWD--LGKGDFR 357 (805)
2830 Q Consensus 307 ----ifkeaekffvsvglpn---mtqgfwensm----------------ltdp----gnvqkavchptawd--lgkgdfr 357 (805)
2831 +|+.+++.| |+-- ....+|..+. .-|+ |.-..+-|.+..-. ....+.+
2832 T Consensus 365 ~~~~l~~~~~~~f---g~~~~~~~~~~~W~~~v~~~~v~~~~~~~lg~~y~D~~~r~~K~~~~~~~~~~~~~~~~~~~p~ 441 (680)
2833 T 1Y79_1 365 LNEGVFWTANQLF---GIKFVERFDIPVYHPDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNKTHPV 441 (680)
2834 T ss_pred HHHhHHHHHHHHh---CCEEEEcCCCccccCCceEEEEEcCCCCEEEEEEEeCCCCCCCCCCCcccceecccCCCCCCCE
2835 Confidence 444555544 2111 0111233322 1121 22222223221000 0012344
2836
2837
2838 Q sp|Q9BYF1|ACE2 358 I-----------LMCTKVTMDDFLTAHHEMGHIQYDMAYAAQ-PFLLRNGANEGFHEAVGEIMSLSAATPKHLKSIGLLS 425 (805)
2839 Q Consensus 358 i-----------lmctkvtmddfltahhemghiqydmayaaq-pfllrnganegfheavgeimslsaatpkhlksiglls 425 (805)
2840 | -.|+.++.+|+.|.+||+||..+.+..... +.+...+..-.|.|+.+.+|..-+..|..|+.++.--
2841 T Consensus 442 v~~~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~~~~~~~~~~d~~E~~S~~~E~~~~~~~~l~~~~~~~ 521 (680)
2842 T 1Y79_1 442 IYNVCNYQKPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHWATHPQVFARYARHY 521 (680)
2843 T ss_pred EEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHhCCCCchhcCCCCcccccccchHhhHHHhcCHHHHHHHhhcC
2844 Confidence 4 267778899999999999999998776543 2222344678899999999999999999999876432
2845
2846
2847 Q sp|Q9BYF1|ACE2 426 PDFQEDNETEINFLLK-----QALTIVGTLPFTYMLEKWRWMVFKGE--IPKDQWMKKWWEMKREIVGVVEPVPHDETYC 498 (805)
2848 Q Consensus 426 pdfqedneteinfllk-----qaltivgtlpftymlekwrwmvfkge--ipkdqwmkkwwemkreivgvvepvphdetyc 498 (805)
2849 .+-+.-.+..++.|++ +++.++..+.+ ..++.+-+-...++ +..+++ .||+...+-.|+ .+.+ ..+.
2850 T Consensus 522 ~~~~~l~~~~~~~l~~~~~~~~~~~~~~~l~~-~~~D~~lh~~~~~~~~~~~~~~--~~~~~~~~~~~~-~~~~--~~~~ 595 (680)
2851 T 1Y79_1 522 QSGAAMPDELQQKMRNASLFNKGYEMSELLSA-ALLDMRWHCLEENEAMQDVDDF--ELRALVAENMDL-PAIP--PRYR 595 (680)
2852 T ss_pred CCCCCCCHHHHHHHHHHhhHHHHHHHHHHHHH-HHHHHHHhcCCCCCCCCChhHH--HHHHHHHHHHCC-CCCC--CCcc
2853 Confidence 1111112334555543 35555555544 46666555444332 333444 455544434465 2222 2333
2854
2855
2856 Q sp|Q9BYF1|ACE2 499 DPASLFHVSN-DYS--FIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGKSEPWTLALENVV 574 (805)
2857 Q Consensus 499 dpaslfhvsn-dys--firyytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgksepwtlalenvv 574 (805)
2858 +.+..|+.. +|. +..|....++.+++.+.+|+ +|++ +.++|+++. .+|..|.+.++.-.++...
2859 T Consensus 596 -~~~~~hi~~~~y~~~yysY~~s~v~a~~i~~~~~~----~~~~-------~~~~g~~~r~~~L~~G~s~~~~e~~~~fl 663 (680)
2860 T 1Y79_1 596 -SSYFAHIFGGGYAAGYYAYLWTQMLADDGYQWFVE----QGGL-------TRENGLRFREAILSRGNSEDLERLYRQWR 663 (680)
2861 T ss_pred -ccccHHHHcCCcchHHHHHHHHHHHHHHHHHHHHH----hCCC-------CHHHHHHHHHHhhccCCCCCHHHHHHHHh
2862 Confidence 677777753 333 23444455555565555544 3443 257899998 8999999999999999998
2863
2864
2865 Q sp|Q9BYF1|ACE2 575 GAKNMNVRPLLNYF 588 (805)
2866 Q Consensus 575 gaknmnvrpllnyf 588 (805)
2867 |.. .+..+++.++
2868 T Consensus 664 G~~-~~~~~~l~~~ 676 (680)
2869 T 1Y79_1 664 GKA-PKIMPMLQHR 676 (680)
2870 T ss_pred CCC-CCHHHHHHHc
2871 Confidence 876 7777777765
2872
2873
2874 No 33
2875 >4KA7_A Oligopeptidase A, short endogenous peptide; Protease, Mitochondria, chloroplast, HYDROLASE-HYDROLASE SUBSTRATE; HET: GOL; 1.8A {Arabidopsis thaliana}
2876 Probab=99.43 E-value=5.8e-17 Score=163.74 Aligned_cols=407 Identities=15% Similarity=0.103 Sum_probs=238.2 Template_Neff=9.500
2877
2878 Q sp|Q9BYF1|ACE2 144 LEPGLNEIMANSLDYNERLWAWESWRSEVG---KQLRPLYEEYVVLKNEMARANHYEDYGDYWRGDYEVNGVDGYDYSRG 220 (805)
2879 Q Consensus 144 lepglneimansldynerlwaweswrsevg---kqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrg 220 (805)
2880 -.|.+..+|.++-|...|--+|++|.+..+ ....+++.+.+.+++++|+...|++|.+|+-.+..+ +..
2881 T Consensus 239 ~~~~~~~il~~~~d~~~Rk~~~~a~~~~~~~~~~~~~~~l~~l~~~R~~~A~llGy~s~a~~~l~~~~~--------~~~ 310 (714)
2882 T 4KA7_A 239 DAPSYLPVMQHAKNRALREEVYRAYLSRASSGDLDNTAIIDQILKLRLEKAKLLGYNNYAEVSMAMKMA--------TVE 310 (714)
2883 T ss_dssp SHHHHHHHHHHCCCHHHHHHHHHHHHTTTCSGGGCCHHHHHHHHHHHHHHHHHTTCSSHHHHHHTTSSC--------CHH
2884 T ss_pred CCccHHHHHHhCCCHHHHHHHHHHHHcccCCCCcChHHHHHHHHHHHHHHHHHhCCCCHHHHHHHHhcC--------CHH
2885 Confidence 346678899999899999999999987654 568899999999999999999999999998654333 222
2886
2887
2888 Q sp|Q9BYF1|ACE2 221 QLIEDVEHTFEEIKPLYEHLHAYVRAKLMNAYPSYISPIGCLPAHLLGDMWGRFWTNLYSLTVPFGQK-PNIDVTDAMVD 299 (805)
2889 Q Consensus 221 qliedvehtfeeikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqk-pnidvtdamvd 299 (805)
2890 .+.+-++...+.++|+++..++.++......+. . |.---..|...|-.. ++-+. .+++ ...+.
2891 T Consensus 311 ~v~~~L~~l~~~~~~~~~~~~~~l~~~~~~~~~--------~-----~~~~l~~wD~~y~~~-~~~~~~~~~~--~~~~~ 374 (714)
2892 T 4KA7_A 311 KAAELLEKLRSASWDAAVQDMEDLKSFAKNQGA--------A-----ESDSMTHWDTTFWSE-RLRESKYDIN--EEELR 374 (714)
2893 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTC--------G-----GGGSCCTTTHHHHHH-HHHHHHHCCC--HHHHG
2894 T ss_pred HHHHHHHHHHHhcHHHHHHHHHHHHHHHHHcCC--------C-----CCCCCCcccHHHHHH-HHHHhcCCCC--HHHHH
2895 Confidence 333444445556677777666666643222111 0 000012333332222 11111 1111 11111
2896
2897
2898 Q sp|Q9BYF1|ACE2 300 QAWD----AQRIFKEAEKFFVSVGLPNMT--QGFWENSM----------------LTDP----G-NVQKAVCHPTAWD-- 350 (805)
2899 Q Consensus 300 qawd----aqrifkeaekffvsvglpnmt--qgfwensm----------------ltdp----g-nvqkavchptawd-- 350 (805)
2900 .-.. ...+|+-++++|- +++.... ...|..+. .-|+ | ....+.|++..-.
2901 T Consensus 375 ~yf~~~~~~~~i~~~~~~~f~-l~~~~~~~~~~~w~~~v~~~~v~~~~~~~~g~~~lD~~~r~~kk~~g~~~~~~~~~~~ 453 (714)
2902 T 4KA7_A 375 PYFSLPKVMDGLFSLAKTLFG-IDIEPADGLAPVWNNDVRFYRVKDSSGNPIAYFYFDPYSRPSEKRGGAWMDEVVSRSR 453 (714)
2903 T ss_dssp GGCBHHHHHHHHHHHHHHHHC-CEEEECTTSSCCSSTTCEEEEEECTTSCEEEEEEEEEECCTTTSCSSCEEEEEECCBS
2904 T ss_pred hcCCHHHHHHHHHHHHHHHHC-cEEEECCCCCCcccCCcEEEEEEcCCCCeEEEEEECCCCCCCCCCCCcccccccccch
2905 Confidence 1111 2345555566655 4444332 12343322 1222 2 1222334322110
2906
2907
2908 Q sp|Q9BYF1|ACE2 351 -LG-----KGDFRILMC-----------TKVTMDDFLTAHHEMGHIQYDMAYAAQPFLLR--NGANEGFHEAVGEIMSLS 411 (805)
2909 Q Consensus 351 -lg-----kgdfrilmc-----------tkvtmddfltahhemghiqydmayaaqpfllr--nganegfheavgeimsls 411 (805)
2910 ++ .....|+|+ +.++.+|+.|.+||+||..+.+....+...+. .+..-.|.|+.+.+|..-
2911 T Consensus 454 ~~~~~~~~~~~p~v~~~~n~~~~~~~~~~ll~~~~v~tl~HE~GHalh~~l~~~~~~~~~g~~~~~~d~~E~~S~~~E~~ 533 (714)
2912 T 4KA7_A 454 VMAQKGSSVRLPVAHMVCNQTPPVGDKPSLMTFREVETVFHQFGHALQHMLTKQDEGLVAGIRNIEWDAVELPSQFMENW 533 (714)
2913 T ss_dssp TTCCTTSSCBCCEEEEEEEECCCCTTSCCBCCHHHHHHHHHHHHHHHHHHSCCCCCGGGSTTTTCCGGGTTHHHHHHHGG
2914 T ss_pred hHhcCCCceeccEEEEEecCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHhhCCCchhhcCccccccccchhcHHHHHHH
2915 Confidence 00 123456654 44569999999999999999887765554444 256889999999999999
2916
2917
2918 Q sp|Q9BYF1|ACE2 412 AATPKHLKSIGLLSPDFQEDNETEINFLLKQ-----ALTIVGTLPFTYMLEKWRWMVFKGEIPKDQWMKKWWEMKREIVG 486 (805)
2919 Q Consensus 412 aatpkhlksigllspdfqedneteinfllkq-----altivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivg 486 (805)
2920 +..|..|+.++.-..+-++..+..++.+++. ++.++. .++-..++.+.+-...+.-| ..+-+-|+++..+. |
2921 T Consensus 534 ~~~~~~L~~~~~~~~~~~~~~~~~~~~l~~~~~~~~~~~~~~-~~~~~~~D~~lh~~~~~~~~-~~~~~~~~~~~~~~-~ 610 (714)
2922 T 4KA7_A 534 CYHRDTLMSIAKHYETGETLPEEVYKKLLAARTFRAGSFSLR-QLKFASVDLELHTKYVPGGP-ESIYDVDQRVSVKT-Q 610 (714)
2923 T ss_dssp GGSHHHHHHHCBCTTTCCBCCHHHHHHHHHTTTTTHHHHHHH-HHHHHHHHHHHTTTCCTTSS-CCHHHHHHHHHHHH-C
2924 T ss_pred hcCHHHHHHHhhccCCCCCCCHHHHHHHHHHhhhchHHHHHH-HHHHHHHHHHHHhcCCCCCC-CCHHHHHHHHHHHh-C
2925 Confidence 9999999887653322222233446666654 555544 55667788877776643323 23335577664444 3
2926
2927
2928 Q sp|Q9BYF1|ACE2 487 VVEPVPHDETYCDPASLFHVSN-DY--SFIRYYTRTLYQFQFQEALCQAAKHEGPLHKCDISNSTEAGQKLF-NMLRLGK 562 (805)
2929 Q Consensus 487 vvepvphdetycdpaslfhvsn-dy--sfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklf-nmlrlgk 562 (805)
2930 -+.+.+ ..-.+.+..|+-. +| .+..|-...++.+++-+.+|+ +|+. +...+.++|+++. ++|..|.
2931 T Consensus 611 ~~~~~~---~~~~~~~~~hi~~~~y~a~yY~Y~~a~v~a~~i~~~f~~----~~~~---~~~~~~~~g~~~~~~~L~~G~ 680 (714)
2932 T 4KA7_A 611 VIPPLP---EDRFLCSFSHIFAGGYAAGYYSYKWAEVLSADAFSAFED----AGLD---DIKAVKETGQRFRNTILALGG 680 (714)
2933 T ss_dssp SSCCCT---TCCGGGGCHHHHSSTTTTTTTHHHHHHHHHHHHHHHHHH----HCTT---CHHHHHHHHHHHHTTTTTCTT
2934 T ss_pred CCCCCC---CCcccccchhhhccCcchHHHHHHHHHHHHHHHHHHHHH----cCCC---chHHHHHHHHHHHHHHhhcCC
2935 Confidence 232211 1124456666643 44 444554455555555554444 2321 2234678999999 9999999
2936
2937
2938 Q sp|Q9BYF1|ACE2 563 SEPWTLALENVVGAKNMNVRPLLNYFE 589 (805)
2939 Q Consensus 563 sepwtlalenvvgaknmnvrpllnyfe 589 (805)
2940 +.++.-.++...|.. .+..+++.++.
2941 T Consensus 681 s~~~~e~~~~~~g~~-~~~~~~l~~~~ 706 (714)
2942 T 4KA7_A 681 GKAPLKVFVEFRGRE-PSPEPLLRHNG 706 (714)
2943 T ss_dssp SSCHHHHHHHHHSSC-CCSHHHHHHTT
2944 T ss_pred CCCHHHHHHHHhCCC-CChHHHHHHcC
2945 Confidence 999999998877764 66777777653
2946
2947
2948 No 34
2949 >2KNC_B Integrin alpha-IIb, Integrin beta-3; integrin, transmembrane signaling, protein structure; NMR {Homo sapiens}
2950 Probab=92.66 E-value=0.036 Score=45.32 Aligned_cols=31 Identities=13% Similarity=0.358 Sum_probs=11.0 Template_Neff=7.700
2951
2952 Q sp|Q9BYF1|ACE2 733 PPNQPPVSIWLIVFGVVMGVIVVGIVILIFT 763 (805)
2953 Q Consensus 733 ppnqppvsiwlivfgvvmgvivvgivilift 763 (805)
2954 .+...+.+.+.|+.|++.|++++|++++++.
2955 T Consensus 2 ~~~~~~~~~~~i~g~vvggiv~l~ll~~~i~ 32 (79)
2956 T 2KNC_B 2 AMGSKGPDILVVLLSVMGAILLIGLAALLIW 32 (79)
2957 T ss_dssp CSSCS-------------SHHHHHHHHHHHH
2958 T ss_pred CCCCCcCchHHHHHHHHHHHHHHHHHHHHHH
2959 Confidence 3455677788888888888887777654433
2960
2961
2962 No 35
2963 >2L8S_A Integrin alpha-1; Integrin Alpha1, Transmembrane Region, Detergent; NMR {Homo sapiens}
2964 Probab=87.55 E-value=0.29 Score=40.19 Aligned_cols=43 Identities=26% Similarity=0.506 Sum_probs=30.9 Template_Neff=5.400
2965
2966 Q sp|Q9BYF1|ACE2 736 QPPVSIWLIVFGVVMGVIVVGIVILIF--TGIRDRKKKNKARSGE 778 (805)
2967 Q Consensus 736 qppvsiwlivfgvvmgvivvgivilif--tgirdrkkknkarsge 778 (805)
2968 .+++.+|.|+.+++.|++++++++++. .|.-.||++.+....|
2969 T Consensus 4 ~~~~p~wiii~svl~GlllL~iii~iL~K~GFFkRk~~~~~~~~~ 48 (54)
2970 T 2L8S_A 4 PGRVPLWVILLSAFAGLLLLMLLILALWKIGFFKRPLKKKMEKLE 48 (54)
2971 T ss_dssp CCCCCTHHHHHHHHHHHHHHHHHHHHHHHHHHTTSCCSCCCCC--
2972 T ss_pred CCCccHHHHHHHHHHHHHHHHHHHHHHHHcCCCCCCcchHHHHhc
2973 Confidence 467889999999999998877765554 5777777766655444
2974
2975
2976 No 36
2977 >2N2A_B Receptor tyrosine-protein kinase erbB-2; HER2, ErbB2, Tyrosine kinase, Activation; NMR {Homo sapiens}
2978 Probab=86.49 E-value=0.38 Score=38.36 Aligned_cols=30 Identities=27% Similarity=0.208 Sum_probs=13.8 Template_Neff=7.000
2979
2980 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
2981 Q Consensus 742 wlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
2982 ..|+.||+.|++++.++++++.-++.|+++
2983 T Consensus 9 ~~I~~~Vvg~l~~~~~i~~~~~~~~Rrr~~ 38 (58)
2984 T 2N2A_B 9 TSIISAVVGILLVVVLGVVFGILIKRRQQK 38 (58)
2985 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHTTC
2986 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHhHHHH
2987 Confidence 345556655555444444333333434333
2988
2989
2990 No 37
2991 >2KNC_A Integrin alpha-IIb, Integrin beta-3; integrin, transmembrane signaling, protein structure; NMR {Homo sapiens}
2992 Probab=85.75 E-value=0.45 Score=38.68 Aligned_cols=40 Identities=23% Similarity=0.570 Sum_probs=29.1 Template_Neff=5.900
2993
2994 Q sp|Q9BYF1|ACE2 735 NQPPVSIWLIVFGVVMGVIVVGIVILI--FTGIRDRKKKNKA 774 (805)
2995 Q Consensus 735 nqppvsiwlivfgvvmgvivvgivili--ftgirdrkkknka 774 (805)
2996 ..+++++|.|+.+++.|++++++++++ -.|...||++...
2997 T Consensus 6 ~~~~~~~wiiv~svl~GlllL~li~~iL~K~GFFkRk~~~~~ 47 (54)
2998 T 2KNC_A 6 EERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNRPPLE 47 (54)
2999 T ss_dssp TTTTCCHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTCCSCC
3000 T ss_pred ccccccHHHHHHHHHHHHHHHHHHHHHHHHcCccccCCCccc
3001 Confidence 345788999999999999887766544 4577777665543
3002
3003
3004 No 38
3005 >2M3E_A Integrin alpha-L; integrin alpah L TM domain; NMR {Homo sapiens}
3006 Probab=85.42 E-value=0.48 Score=38.20 Aligned_cols=39 Identities=18% Similarity=0.400 Sum_probs=29.1 Template_Neff=5.700
3007
3008 Q sp|Q9BYF1|ACE2 736 QPPVSIWLIVFGVVMGVIVVGIVILIF--TGIRDRKKKNKA 774 (805)
3009 Q Consensus 736 qppvsiwlivfgvvmgvivvgivilif--tgirdrkkknka 774 (805)
3010 ..++.+|.|+.+++.|++++.+++++. .|...||++.+.
3011 T Consensus 7 ~~~~~~wiii~svi~GlllL~ii~~iL~K~GFFkRk~~~~~ 47 (50)
3012 T 2M3E_A 7 YEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKM 47 (50)
3013 T ss_dssp TTCCCHHHHHHHHHHHHHHHHHHHHHHHHHTSGGGSCCCCC
3014 T ss_pred chhhcHHHHHHHHHHHHHHHHHHHHHHHHcCcchhhhhHHH
3015 Confidence 457889999999999998877765554 566677666543
3016
3017
3018 No 39
3019 >6J8H_C Sodium channel subunit beta-2, Sodium; voltage-gated sodium channel, MEMBRANE PROTEIN; HET: 9SL, NAG;{Homo sapiens}
3020 Probab=84.27 E-value=0.6 Score=37.23 Aligned_cols=8 Identities=13% Similarity=0.576 Sum_probs=3.9 Template_Neff=12.500
3021
3022 Q sp|Q9BYF1|ACE2 591 LFTWLKDQ 598 (805)
3023 Q Consensus 591 lftwlkdq 598 (805)
3024 -++|.++.
3025 T Consensus 64 ~v~W~~~~ 71 (215)
3026 T 6J8H_C 64 SLNWTYQE 71 (215)
3027 T ss_pred EEEEEEec
3028 Confidence 34555543
3029
3030
3031 No 40
3032 >2N9Y_B Integrin alpha-IIb, Integrin beta-3; transmembrane complex, integrin receptor, cell; NMR {Homo sapiens}
3033 Probab=83.96 E-value=0.63 Score=34.96 Aligned_cols=30 Identities=13% Similarity=0.345 Sum_probs=21.3 Template_Neff=7.200
3034
3035 Q sp|Q9BYF1|ACE2 737 PPVSIWLIVFGVVMGVIVVGIVILIFTGIR 766 (805)
3036 Q Consensus 737 ppvsiwlivfgvvmgvivvgiviliftgir 766 (805)
3037 ++.+++.|+.|++-|++++|+++++..-.+
3038 T Consensus 5 ~~~~~~~I~ggvvggi~ligli~lli~~~~ 34 (43)
3039 T 2N9Y_B 5 KCPDILVVLLSVMGAILLIGLAPLLIWKLL 34 (43)
3040 T ss_dssp SSCCHHHHHHHHHHHHHHHHHHHHHHHHHH
3041 T ss_pred CCCcHHHHHHHHHHHHHHHHHHHHHHHHHH
3042 Confidence 345667788899999888887766554443
3043
3044
3045 No 41
3046 >6JXR_n T-cell surface glycoprotein CD3 zeta; IMMUNE SYSTEM;{Homo sapiens}
3047 Probab=83.38 E-value=0.7 Score=37.95 Aligned_cols=7 Identities=14% Similarity=0.700 Sum_probs=3.7 Template_Neff=12.900
3048
3049 Q sp|Q9BYF1|ACE2 591 LFTWLKD 597 (805)
3050 Q Consensus 591 lftwlkd 597 (805)
3051 -+.|.++
3052 T Consensus 154 ~~~W~~~ 160 (291)
3053 T 6JXR_n 154 ELSWWVN 160 (291)
3054 T ss_pred eEEEEEC
3055 Confidence 4556553
3056
3057
3058 No 42
3059 >2K9J_A Integrin alpha-IIb light chain, Integrin; integrin, transmembrane complex, Cell adhesion; NMR {Homo sapiens}
3060 Probab=83.01 E-value=0.74 Score=35.92 Aligned_cols=39 Identities=26% Similarity=0.696 Sum_probs=28.8 Template_Neff=5.800
3061
3062 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIF--TGIRDRKK 770 (805)
3063 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgivilif--tgirdrkk 770 (805)
3064 ||+..+++.+|.|+.+++.|++++.+++++. .|.-.||+
3065 T Consensus 1 ~~~~~~~~~~wiii~svl~GlllL~li~~iL~K~GFFkRk~ 41 (42)
3066 T 2K9J_A 1 GALEERAIPIWWVLVGVLGGLLLLTILVLAMWKVGFFKRNR 41 (42)
3067 T ss_dssp CCSSCSCCHHHHHHHHHHHHHHHHHHHHHHHHTTTSSCCCC
3068 T ss_pred CchhhccccHHHHHHHHHHHHHHHHHHHHHHHHhCccccCC
3069 Confidence 5667788999999999999998887765554 34444443
3070
3071
3072 No 43
3073 >2N5S_A Epidermal growth factor receptor (E.C.2.7.10.1); transmembrane, TRANSFERASE; NMR {Homo sapiens}
3074 Probab=82.67 E-value=0.79 Score=34.05 Aligned_cols=10 Identities=30% Similarity=0.504 Sum_probs=4.2 Template_Neff=8.700
3075
3076 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVI 753 (805)
3077 Q Consensus 744 ivfgvvmgvi 753 (805)
3078 |+.|++.|++
3079 T Consensus 8 i~~gvv~~~~ 17 (54)
3080 T 2N5S_A 8 IATGMVGALL 17 (54)
3081 T ss_dssp TTHHHHHHHH
3082 T ss_pred HHHHHHHHHH
3083 Confidence 3444444433
3084
3085
3086 No 44
3087 >4UM8_D INTEGRIN ALPHA-V, INTEGRIN BETA-6; IMMUNE SYSTEM, CELL SURFACE RECEPTOR; HET: CAC, SO4, NAG, CA, MAN, BMA; 2.852A {HOMO SAPIENS}
3088 Probab=80.82 E-value=1 Score=48.98 Aligned_cols=25 Identities=32% Similarity=0.786 Sum_probs=0.0 Template_Neff=9.100
3089
3090 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3091 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3092 +..+|.|++|++.|++++|+++|+.
3093 T Consensus 705 ~~~~~~i~~gvv~~ivli~l~~l~i 729 (788)
3094 T 4UM8_D 705 PPNIPMIMLGVSLAILLIGVVLLCI 729 (788)
3095 T ss_dssp -------------------------
3096 T ss_pred CCCHHHHHHHHHHHHHHHHHHHHHH
3097 Confidence 5667788889888888888776654
3098
3099
3100 No 45
3101 >4UM8_B INTEGRIN ALPHA-V, INTEGRIN BETA-6; IMMUNE SYSTEM, CELL SURFACE RECEPTOR; HET: MAN, NAG, CA, SO4, CAC, BMA; 2.852A {HOMO SAPIENS}
3102 Probab=78.69 E-value=1.4 Score=48.08 Aligned_cols=25 Identities=32% Similarity=0.786 Sum_probs=19.0 Template_Neff=9.100
3103
3104 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3105 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3106 +..+|.|++|++.|++++|+++|+.
3107 T Consensus 705 ~~~~~~i~~gvv~~ivll~l~~lli 729 (788)
3108 T 4UM8_B 705 PPNIPMIMLGVSLAILLIGVVLLCI 729 (788)
3109 T ss_pred CchHHHHHHHHHHHHHHHHHHHHHH
3110 Confidence 5677888888888888887766543
3111
3112
3113 No 46
3114 >1AFO_A GLYCOPHORIN A; INTEGRAL MEMBRANE PROTEIN, HUMAN GLYCOPHORIN; NMR {Homo sapiens} SCOP: j.35.1.1
3115 Probab=75.93 E-value=1.9 Score=35.46 Aligned_cols=37 Identities=46% Similarity=0.680 Sum_probs=25.9 Template_Neff=2.500
3116
3117 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3118 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3119 .++-+.|+ |.+|+|||+.|+ +|++++|-..||.-+||
3120 T Consensus 4 ~h~fs~p~-i~lII~~VmaGI--IG~Il~i~y~I~rl~kk 40 (40)
3121 T 1AFO_A 4 AHHFSEPE-ITLIIFGVMAGV--IGTILLISYGIRRLIKK 40 (40)
3122 T ss_dssp SCCSSCCH-HHHHHHHHHHHH--HHHHHHHHHHHHHHSCC
3123 T ss_pred ccCCChHH-HHHHHHHHHHHH--HHHHHHHHHHHHHHhcC
3124 Confidence 34445555 789999999987 46777777777765554
3125
3126
3127 No 47
3128 >6A69_B Plasma membrane calcium-transporting ATPase 1; Membrane protein, STRUCTURAL PROTEIN; HET: NAG; 4.11A {Homo sapiens}
3129 Probab=75.89 E-value=1.9 Score=35.66 Aligned_cols=15 Identities=13% Similarity=0.375 Sum_probs=6.6 Template_Neff=12.700
3130
3131 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGVIVVG 756 (805)
3132 Q Consensus 742 wlivfgvvmgvivvg 756 (805)
3133 +.+++|++++++++.
3134 T Consensus 224 ~~~~~~~~~~~~~~~ 238 (282)
3135 T 6A69_B 224 LWPFLGILAEIIILV 238 (282)
3136 T ss_pred HHHHHHHHHHHHHHH
3137 Confidence 334445444444433
3138
3139
3140 No 48
3141 >6AGF_B Sodium channel protein PaFPC1, Mu-diguetoxin-Dc1a; sodium channel, MEMBRANE PROTEIN; HET: 6OU, 9Z9, NAG, BMA; 3.2A {Homo sapiens}
3142 Probab=75.28 E-value=2 Score=35.68 Aligned_cols=22 Identities=18% Similarity=0.176 Sum_probs=0.4 Template_Neff=11.700
3143
3144 Q sp|Q9BYF1|ACE2 773 KARSGENPYASIDISKGENNPGF 795 (805)
3145 Q Consensus 773 karsgenpyasidiskgennpgf 795 (805)
3146 +.+..+.+|+.+... ..+|+..
3147 T Consensus 192 ~~~~~~~~~~~~~~~-~~~~~~~ 213 (218)
3148 T 6AGF_B 192 AAQENASEYLAITSE-SKENCTG 213 (218)
3149 T ss_dssp C----------------------
3150 T ss_pred HHHhhHhhhcccChh-hhhcccc
3151 Confidence 344446677766533 3344433
3152
3153
3154 No 49
3155 >6J8J_B Sodium channel subunit beta-2, Sodium; voltage-gated sodium channel, MEMBRANE PROTEIN; HET: 9SR, NAG;{Homo sapiens}
3156 Probab=75.28 E-value=2 Score=35.68 Aligned_cols=22 Identities=18% Similarity=0.176 Sum_probs=11.0 Template_Neff=11.700
3157
3158 Q sp|Q9BYF1|ACE2 773 KARSGENPYASIDISKGENNPGF 795 (805)
3159 Q Consensus 773 karsgenpyasidiskgennpgf 795 (805)
3160 +.+..+.+|+.+... ..+|+..
3161 T Consensus 192 ~~~~~~~~~~~~~~~-~~~~~~~ 213 (218)
3162 T 6J8J_B 192 AAQENASEYLAITSE-SKENCTG 213 (218)
3163 T ss_pred HHHhhHhhhcccChh-hhhcccc
3164 Confidence 344446677766533 3344433
3165
3166
3167 No 50
3168 >6C14_A Protocadherin-15, LHFPL tetraspan subfamily member; PCDH15, LHFPL5, protocadherin, tip link;{Mus musculus}
3169 Probab=74.52 E-value=2.2 Score=40.59 Aligned_cols=23 Identities=4% Similarity=0.128 Sum_probs=12.6 Template_Neff=10.000
3170
3171 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVIL 760 (805)
3172 Q Consensus 738 pvsiwlivfgvvmgvivvgivil 760 (805)
3173 +..+.+|+++++++++++.++++
3174 T Consensus 238 ~~~~~li~laill~l~~lili~~ 260 (337)
3175 T 6C14_A 238 YTEGALLALAFIIILCCIPAILV 260 (337)
3176 T ss_dssp SHHHHHHHHHHHHHHHHHHHHHH
3177 T ss_pred HHHHHHHHHHHHHHHHHHHHHHH
3178 Confidence 33556677776666654433333
3179
3180
3181 No 51
3182 >6UJB_B Integrin alpha-V, Integrin beta-8, C6D4; glycoprotein, adhesion, signaling, SIGNALING PROTEIN-IMMUNE; HET: MAN, NAG, BMA; 3.51A {Homo sapiens}
3183 Probab=73.28 E-value=2.5 Score=45.78 Aligned_cols=25 Identities=16% Similarity=0.359 Sum_probs=0.0 Template_Neff=9.100
3184
3185 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3186 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3187 +..+|.|++|++.+++++++++|++
3188 T Consensus 637 ~~~~~~i~~~v~~~illi~l~~l~i 661 (727)
3189 T 6UJB_B 637 SPSYLRIFFIIFIVTFLIGLLKVLI 661 (727)
3190 T ss_dssp -------------------------
3191 T ss_pred CccHHHHHHHHHHHHHHHHHHHHHH
3192 Confidence 4567788888888887777665543
3193
3194
3195 No 52
3196 >6UJA_B Integrin alpha-V, Integrin beta-8, Transforming; glycoprotein, adhesion, signaling, SIGNALING PROTEIN; HET: MAN, BMA, NAG; 3.3A {Homo sapiens}
3197 Probab=73.28 E-value=2.5 Score=45.78 Aligned_cols=25 Identities=16% Similarity=0.359 Sum_probs=0.0 Template_Neff=9.100
3198
3199 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIF 762 (805)
3200 Q Consensus 738 pvsiwlivfgvvmgvivvgivilif 762 (805)
3201 +..+|.|++|++.+++++++++|++
3202 T Consensus 637 ~~~~~~i~~~v~~~illi~l~~l~i 661 (727)
3203 T 6UJA_B 637 SPSYLRIFFIIFIVTFLIGLLKVLI 661 (727)
3204 T ss_dssp -------------------------
3205 T ss_pred CccHHHHHHHHHHHHHHHHHHHHHH
3206 Confidence 4567788888888887777665543
3207
3208
3209 No 53
3210 >2M20_A Epidermal growth factor receptor (E.C.2.7.10.1); Transmembrane, Cell Signaling, Juxtamembrane, SIGNALING; NMR {Homo sapiens}
3211 Probab=72.68 E-value=2.6 Score=32.92 Aligned_cols=10 Identities=30% Similarity=0.511 Sum_probs=4.3 Template_Neff=7.900
3212
3213 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVI 753 (805)
3214 Q Consensus 744 ivfgvvmgvi 753 (805)
3215 |+.|||.|++
3216 T Consensus 5 i~~~vvg~~~ 14 (60)
3217 T 2M20_A 5 IATGLVGALL 14 (60)
3218 T ss_dssp HHHHHHHHHH
3219 T ss_pred HHHHHHHHHH
3220 Confidence 3444444433
3221
3222
3223 No 54
3224 >5OR7_C Capsid protein, CMRF35-like molecule 1; CR10, sCD300lf, complex, VIRAL PROTEIN; 2.046A {Murine norovirus GV/CR10/2005/USA}
3225 Probab=72.61 E-value=2.7 Score=38.46 Aligned_cols=6 Identities=17% Similarity=0.506 Sum_probs=2.6 Template_Neff=11.000
3226
3227 Q sp|Q9BYF1|ACE2 592 FTWLKD 597 (805)
3228 Q Consensus 592 ftwlkd 597 (805)
3229 +.|.++
3230 T Consensus 52 v~W~~~ 57 (330)
3231 T 5OR7_C 52 KYWCQG 57 (330)
3232 T ss_pred EEEEEC
3233 Confidence 344443
3234
3235
3236 No 55
3237 >2MFR_A Insulin receptor (E.C.2.7.10.1); insulin recepotr, membrane protein, detergent; NMR {Homo sapiens}
3238 Probab=69.03 E-value=3.6 Score=33.93 Aligned_cols=38 Identities=21% Similarity=0.174 Sum_probs=19.5 Template_Neff=5.900
3239
3240 Q sp|Q9BYF1|ACE2 740 SIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNKARSGEN 779 (805)
3241 Q Consensus 740 siwlivfgvvmgvivvgiviliftgirdrkkknkarsgen 779 (805)
3242 +++++++|.+..++++.+++. ...-.+|||+..|+||.
3243 T Consensus 15 ~~~~iiI~pvi~iilii~~~~--~~~~~~kKr~~~~~~~~ 52 (57)
3244 T 2MFR_A 15 NIAKIIIGPLIFVFLFSVVIG--SIYLFLRKRQPDGPLEH 52 (57)
3245 T ss_dssp HHHHHHHHHHHHHHHHHHHHH--HHHHHHTSSCCCCSSSC
3246 T ss_pred hHHHHHHHHHHHHHHHHHHHH--HHHHHHhccCCCCCCCC
3247 Confidence 344555555544443332222 22344566777788874
3248
3249
3250 No 56
3251 >4U0Q_B Plasmodium falciparum Reticulocyte-binding protein homologue; Malaria Erythrocyte invasion, signaling protein; 3.1A {Plasmodium falciparum}
3252 Probab=67.25 E-value=4.2 Score=33.78 Aligned_cols=13 Identities=31% Similarity=0.493 Sum_probs=0.0 Template_Neff=12.500
3253
3254 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVIVVG 756 (805)
3255 Q Consensus 744 ivfgvvmgvivvg 756 (805)
3256 +++|++++++++.
3257 T Consensus 211 ~~~~~~~~~~~~~ 223 (269)
3258 T 4U0Q_B 211 PFLGIVAEVLVLV 223 (269)
3259 T ss_dssp -------------
3260 T ss_pred HHHHHHHHHHHHH
3261 Confidence 3445544444443
3262
3263
3264 No 57
3265 >5A2F_A CD166 ANTIGEN; CELL ADHESION, ALCAM, ACTIVATED LEUKOCYTE; HET: EDO, NAG; 1.86A {HOMO SAPIENS}
3266 Probab=63.73 E-value=5.5 Score=38.68 Aligned_cols=11 Identities=18% Similarity=0.585 Sum_probs=0.0 Template_Neff=11.600
3267
3268 Q sp|Q9BYF1|ACE2 589 EPLFTWLKDQN 599 (805)
3269 Q Consensus 589 eplftwlkdqn 599 (805)
3270 .|.++|.++..
3271 T Consensus 442 ~~~i~W~~~~~ 452 (583)
3272 T 5A2F_A 442 KPAIQWTITGS 452 (583)
3273 T ss_dssp -----------
3274 T ss_pred CCEEEEEECCc
3275 Confidence 35566766543
3276
3277
3278 No 58
3279 >2KLU_A T-cell surface glycoprotein CD4; Protein, Cell membrane, Disulfide bond; NMR {Homo sapiens}
3280 Probab=59.80 E-value=7.3 Score=30.35 Aligned_cols=9 Identities=56% Similarity=0.881 Sum_probs=3.7 Template_Neff=8.800
3281
3282 Q sp|Q9BYF1|ACE2 744 IVFGVVMGV 752 (805)
3283 Q Consensus 744 ivfgvvmgv 752 (805)
3284 +++|++.++
3285 T Consensus 12 ~~vg~~~~~ 20 (70)
3286 T 2KLU_A 12 IVLGGVAGL 20 (70)
3287 T ss_dssp HHHHHHHHH
3288 T ss_pred HHHHHHHHH
3289 Confidence 344444443
3290
3291
3292 No 59
3293 >6ENY_C Beta-2-microglobulin, Tapasin, Protein disulfide-isomerase A3; adaptive immunity, antigen processing, chaperone; HET: BGC, MAN, NAG; 5.8A {Homo sapiens}
3294 Probab=58.02 E-value=8.2 Score=37.78 Aligned_cols=9 Identities=11% Similarity=-0.142 Sum_probs=4.5 Template_Neff=10.300
3295
3296 Q sp|Q9BYF1|ACE2 539 LHKCDISNS 547 (805)
3297 Q Consensus 539 lhkcdisns 547 (805)
3298 .+.|.+.+.
3299 T Consensus 248 ~Y~C~~~~~ 256 (428)
3300 T 6ENY_C 248 TYLATIHLP 256 (428)
3301 T ss_pred EEEEEEEcC
3302 Confidence 455555443
3303
3304
3305 No 60
3306 >1S7Q_A H-2 class I histocompatibility antigen; LCMV, MHC class I, immune; 1.99A {Mus musculus} SCOP: d.19.1.1, b.1.1.2
3307 Probab=57.91 E-value=8.2 Score=37.47 Aligned_cols=11 Identities=27% Similarity=0.314 Sum_probs=0.0 Template_Neff=9.700
3308
3309 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGV 752 (805)
3310 Q Consensus 742 wlivfgvvmgv 752 (805)
3311 +.++.+++.++
3312 T Consensus 285 ~~~~~~~~~~~ 295 (348)
3313 T 1S7Q_A 285 ATVAVLVVLGA 295 (348)
3314 T ss_dssp -----------
3315 T ss_pred HHHHHHHHHHH
3316 Confidence 43333444343
3317
3318
3319 No 61
3320 >1S7S_A H-2 class I histocompatibility antigen; LCMV, MHC class I, immune; 1.99A {Mus musculus} SCOP: d.19.1.1, b.1.1.2
3321 Probab=57.91 E-value=8.2 Score=37.47 Aligned_cols=11 Identities=27% Similarity=0.314 Sum_probs=0.0 Template_Neff=9.700
3322
3323 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGV 752 (805)
3324 Q Consensus 742 wlivfgvvmgv 752 (805)
3325 +.++.+++.++
3326 T Consensus 285 ~~~~~~~~~~~ 295 (348)
3327 T 1S7S_A 285 ATVAVLVVLGA 295 (348)
3328 T ss_dssp -----------
3329 T ss_pred HHHHHHHHHHH
3330 Confidence 43333444343
3331
3332
3333 No 62
3334 >2WY3_A MHC CLASS I POLYPEPTIDE-RELATED SEQUENCE; IMMUNE SYSTEM-VIRAL PROTEIN COMPLEX, IMMUNE; HET: PEU, NAG, ACT; 1.8A {HUMAN HERPESVIRUS 5 STRAIN AD169}
3335 Probab=57.28 E-value=8.6 Score=35.83 Aligned_cols=9 Identities=33% Similarity=0.674 Sum_probs=4.8 Template_Neff=10.500
3336
3337 Q sp|Q9BYF1|ACE2 591 LFTWLKDQN 599 (805)
3338 Q Consensus 591 lftwlkdqn 599 (805)
3339 .++|.++..
3340 T Consensus 214 ~~~W~~~~~ 222 (319)
3341 T 2WY3_A 214 TLTWRQDGV 222 (319)
3342 T ss_pred EEEEEECCE
3343 Confidence 356666543
3344
3345
3346 No 63
3347 >6JXR_f T-cell surface glycoprotein CD3 zeta; IMMUNE SYSTEM;{Homo sapiens}
3348 Probab=55.13 E-value=9.8 Score=32.92 Aligned_cols=14 Identities=14% Similarity=-0.228 Sum_probs=6.0 Template_Neff=10.700
3349
3350 Q sp|Q9BYF1|ACE2 741 IWLIVFGVVMGVIV 754 (805)
3351 Q Consensus 741 iwlivfgvvmgviv 754 (805)
3352 +..|++|++.++++
3353 T Consensus 130 i~~iv~g~~~~~l~ 143 (207)
3354 T 6JXR_f 130 VATIVIVDICITGG 143 (207)
3355 T ss_pred HHHHHHHHHHHHHH
3356 Confidence 33344554444333
3357
3358
3359 No 64
3360 >3LB6_C Interleukin-13, Interleukin-13 receptor subunit alpha-2; cytokine, receptor, decoy, decoy receptor; HET: NAG, MLY; 3.05A {Homo sapiens}
3361 Probab=54.78 E-value=10 Score=33.26 Aligned_cols=18 Identities=11% Similarity=0.165 Sum_probs=10.5 Template_Neff=12.600
3362
3363 Q sp|Q9BYF1|ACE2 670 VRVANLKPRISFNFFVTA 687 (805)
3364 Q Consensus 670 vrvanlkprisfnffvta 687 (805)
3365 ..+.+|+|.-.+.|-|.+
3366 T Consensus 293 ~~~~~L~~~~~Y~~~V~a 310 (380)
3367 T 3LB6_C 293 YTLKTTNETRQLCFVVRS 310 (380)
3368 T ss_pred EEEecCCCCceEEEEEEE
3369 Confidence 445566666666665554
3370
3371
3372 No 65
3373 >3LB6_D Interleukin-13, Interleukin-13 receptor subunit alpha-2; cytokine, receptor, decoy, decoy receptor; HET: NAG; 3.05A {Homo sapiens}
3374 Probab=54.78 E-value=10 Score=33.26 Aligned_cols=18 Identities=11% Similarity=0.165 Sum_probs=7.8 Template_Neff=12.600
3375
3376 Q sp|Q9BYF1|ACE2 670 VRVANLKPRISFNFFVTA 687 (805)
3377 Q Consensus 670 vrvanlkprisfnffvta 687 (805)
3378 ..+.+|+|.-.+.|-|.+
3379 T Consensus 293 ~~~~~L~~~~~Y~~~V~a 310 (380)
3380 T 3LB6_D 293 YTLKTTNETRQLCFVVRS 310 (380)
3381 T ss_dssp EEECC----CCEEEEEEE
3382 T ss_pred EEEecCCCCceEEEEEEE
3383 Confidence 445566666666665554
3384
3385
3386 No 66
3387 >6FGB_A IgG receptor FcRn large subunit; FcRn, rozanolixizumab, ECD, Fab, immune; 2.9A {Homo sapiens}
3388 Probab=49.49 E-value=14 Score=35.50 Aligned_cols=10 Identities=10% Similarity=-0.157 Sum_probs=4.5 Template_Neff=10.000
3389
3390 Q sp|Q9BYF1|ACE2 776 SGENPYASID 785 (805)
3391 Q Consensus 776 sgenpyasid 785 (805)
3392 +..+++.+++
3393 T Consensus 311 ~~~~~~~~~~ 320 (342)
3394 T 6FGB_A 311 SLRGDDTGVL 320 (342)
3395 T ss_pred cCCCCCCCCc
3396 Confidence 3344555443
3397
3398
3399 No 67
3400 >4NKQ_B Cytokine receptor common subunit beta; GM-CSF, receptor complex, dodecamer, Disease; HET: NAG; 3.301A {Homo sapiens}
3401 Probab=46.89 E-value=16 Score=32.21 Aligned_cols=18 Identities=17% Similarity=0.263 Sum_probs=10.6 Template_Neff=11.700
3402
3403 Q sp|Q9BYF1|ACE2 670 VRVANLKPRISFNFFVTA 687 (805)
3404 Q Consensus 670 vrvanlkprisfnffvta 687 (805)
3405 ..+.+|+|...+.|-|.+
3406 T Consensus 186 ~~l~~L~p~t~Y~~~V~a 203 (305)
3407 T 4NKQ_B 186 YNFPSSEPRAKHSVKIRA 203 (305)
3408 T ss_pred EEccCCCCCCcEEEEEEE
3409 Confidence 345566666666665554
3410
3411
3412 No 68
3413 >6JXR_g T-cell surface glycoprotein CD3 zeta; IMMUNE SYSTEM;{Homo sapiens}
3414 Probab=43.82 E-value=20 Score=29.72 Aligned_cols=10 Identities=10% Similarity=0.408 Sum_probs=4.0 Template_Neff=11.300
3415
3416 Q sp|Q9BYF1|ACE2 743 LIVFGVVMGV 752 (805)
3417 Q Consensus 743 livfgvvmgv 752 (805)
3418 .|++|++.++
3419 T Consensus 117 ~i~~~~~~~~ 126 (182)
3420 T 6JXR_g 117 GFLFAEIVSI 126 (182)
3421 T ss_pred HHHHHHHHHH
3422 Confidence 3444443333
3423
3424
3425 No 69
3426 >5EH6_A Glycophorin-A; Receptor, lipidic cubic phase, peptides; 1.918A {Homo sapiens}
3427 Probab=43.27 E-value=20 Score=28.46 Aligned_cols=24 Identities=58% Similarity=1.035 Sum_probs=18.2 Template_Neff=2.200
3428
3429 Q sp|Q9BYF1|ACE2 741 IWLIVFGVVMGVIVVGIVILIFTGIR 766 (805)
3430 Q Consensus 741 iwlivfgvvmgvivvgiviliftgir 766 (805)
3431 |.+|+|||..|| +|.++||-..||
3432 T Consensus 4 I~lII~~vmagv--ig~ILlI~y~I~ 27 (30)
3433 T 5EH6_A 4 ITLIIFGVIAGV--IGTILLISYGIR 27 (30)
3434 T ss_dssp HHHHHHHHHHHH--HHHHHHHHHHHH
3435 T ss_pred HHHHHHHHHHHH--HHHHHHHHHHHH
3436 Confidence 778999999987 466666666665
3437
3438
3439 No 70
3440 >5EH4_C Glycophorin-A; Receptor, lipidic cubic phase, peptides; HET: SCH, OLB; 2.81A {Homo sapiens}
3441 Probab=43.27 E-value=20 Score=28.46 Aligned_cols=24 Identities=58% Similarity=1.035 Sum_probs=18.2 Template_Neff=2.200
3442
3443 Q sp|Q9BYF1|ACE2 741 IWLIVFGVVMGVIVVGIVILIFTGIR 766 (805)
3444 Q Consensus 741 iwlivfgvvmgvivvgiviliftgir 766 (805)
3445 |.+|+|||..|| +|.++||-..||
3446 T Consensus 4 I~lII~~vmagv--ig~ILlI~y~I~ 27 (30)
3447 T 5EH4_C 4 ITLIIFGVIAGV--IGTILLISYGIR 27 (30)
3448 T ss_dssp HHHHHHHHHHHH--HHHHHHHHHHHH
3449 T ss_pred HHHHHHHHHHHH--HHHHHHHHHHHH
3450 Confidence 778999999987 466666666665
3451
3452
3453 No 71
3454 >2XQ2_A SODIUM/GLUCOSE COTRANSPORTER; TRANSPORT PROTEIN, INVERTED REPEATS, LEUT-FOLD; HET: PEG; 2.73A {VIBRIO PARAHAEMOLYTICUS}
3455 Probab=39.81 E-value=25 Score=38.03 Aligned_cols=33 Identities=45% Similarity=0.708 Sum_probs=25.2 Template_Neff=8.700
3456
3457 Q sp|Q9BYF1|ACE2 739 VSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKKNK 773 (805)
3458 Q Consensus 739 vsiwlivfgvvmgvivvgiviliftgirdrkkknk 773 (805)
3459 .-||+|+|||..||| |++.+|-.+||.-.||+.
3460 T Consensus 548 ~~~~~~~~~~~~~~~--~~~~~~~~~~~~~~~~~~ 580 (593)
3461 T 2XQ2_A 548 AEITLIIFGVMAGVI--GTILLISYGIKKLIKASY 580 (593)
3462 T ss_pred HHHHHHHHHHHHHHH--HHHHHHHHHHHHHhhcCC
3463 Confidence 346999999998865 677788888887666653
3464
3465
3466 No 72
3467 >2RDD_B Acriflavine resistance protein B, UPF0092; DRUG RESISTANCE, MULTIDRUG EFFLUX, TRANSPORTER; HET: AIC; 3.5A {Escherichia coli}
3468 Probab=39.22 E-value=26 Score=26.11 Aligned_cols=20 Identities=25% Similarity=0.323 Sum_probs=11.5 Template_Neff=6.900
3469
3470 Q sp|Q9BYF1|ACE2 756 GIVILIFTGIRDRKKKNKAR 775 (805)
3471 Q Consensus 756 giviliftgirdrkkknkar 775 (805)
3472 .++++.|.-+|..||+.|++
3473 T Consensus 12 ~~~~~~~~~~rpqkK~~k~~ 31 (37)
3474 T 2RDD_B 12 FGLIFYFMILRPQQKRTKEH 31 (37)
3475 T ss_dssp HHHHHHHHTHHHHHHHHHHH
3476 T ss_pred HHHHHHHHHHCHHHHHHHHH
3477 Confidence 34445555667766666554
3478
3479
3480 No 73
3481 >6CPL_A HLA class II histocompatibility antigen; IMMUNE RECEPTOR, IMMUNE SYSTEM; HET: NAG, SO4; 2.45A {Homo sapiens}
3482 Probab=39.13 E-value=26 Score=31.32 Aligned_cols=8 Identities=38% Similarity=0.904 Sum_probs=4.3 Template_Neff=10.400
3483
3484 Q sp|Q9BYF1|ACE2 591 LFTWLKDQ 598 (805)
3485 Q Consensus 591 lftwlkdq 598 (805)
3486 -.+|.++.
3487 T Consensus 118 ~v~W~~~~ 125 (229)
3488 T 6CPL_A 118 NVTWLRNG 125 (229)
3489 T ss_pred EEEEEECC
3490 Confidence 45666554
3491
3492
3493 No 74
3494 >6EJ2_A Beta-secretase 1 (E.C.3.4.23.46); BACE1, protease, Alzheimer, PEPTIDE BINDING; HET: B7E; 1.46A {Homo sapiens}
3495 Probab=38.02 E-value=28 Score=35.18 Aligned_cols=15 Identities=7% Similarity=0.138 Sum_probs=0.0 Template_Neff=10.200
3496
3497 Q sp|Q9BYF1|ACE2 736 QPPVSIWLIVFGVVM 750 (805)
3498 Q Consensus 736 qppvsiwlivfgvvm 750 (805)
3499 ....++..|+.++|-
3500 T Consensus 452 ~~~~~~~~ivg~~vg 466 (501)
3501 T 6EJ2_A 452 ESTLMTIAYVMAAIC 466 (501)
3502 T ss_dssp ---------------
3503 T ss_pred CCcchHHHHHHHHHH
3504 Confidence 334444444444333
3505
3506
3507 No 75
3508 >6ENY_F Beta-2-microglobulin, Tapasin, Protein disulfide-isomerase A3; adaptive immunity, antigen processing, chaperone; HET: NAG, MAN, BGC; 5.8A {Homo sapiens}
3509 Probab=37.88 E-value=28 Score=33.91 Aligned_cols=6 Identities=50% Similarity=1.359 Sum_probs=2.8 Template_Neff=9.700
3510
3511 Q sp|Q9BYF1|ACE2 592 FTWLKD 597 (805)
3512 Q Consensus 592 ftwlkd 597 (805)
3513 .+|.++
3514 T Consensus 215 v~W~~~ 220 (341)
3515 T 6ENY_F 215 LTWQRD 220 (341)
3516 T ss_dssp EEEEET
3517 T ss_pred EEEEeC
3518 Confidence 445444
3519
3520
3521 No 76
3522 >5XTH_0 NADH dehydrogenase [ubiquinone] flavoprotein 1; Homo sapiens, Oxidoreductase, Respiratory, Supercomplex; HET: PEE, CDL, HEA, HEC, FES, PLX, 8Q1, HEM, NDP, SF4, FMN; 3.9A {Homo sapiens}
3523 Probab=37.10 E-value=29 Score=33.41 Aligned_cols=32 Identities=22% Similarity=0.281 Sum_probs=22.9 Template_Neff=5.900
3524
3525 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFT 763 (805)
3526 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgivilift 763 (805)
3527 ||+-++|..-|-.|+|.++++|.+++++.++.
3528 T Consensus 65 ~~e~~~p~g~wK~v~~~v~~~~~~s~~lf~~~ 96 (144)
3529 T 5XTH_0 65 FAEMNRSTNEWKTVVGAAMFFIGFTALLLIWE 96 (144)
3530 T ss_pred cccccCCCchHHHHHHHHHHHHHHHHHHHHHH
3531 Confidence 45667888889888888887776666555543
3532
3533
3534 No 77
3535 >5B1A_D Cytochrome c oxidase subunit 1; Oxidoreductase, Proton pump, Heme, Respiratory; HET: FME, CDL, TGL, HEA, PGV, CHD, PSC, PEK, DMU, TPO, SAC; 1.5A {Bos taurus}
3536 Probab=33.75 E-value=36 Score=33.09 Aligned_cols=32 Identities=22% Similarity=0.281 Sum_probs=22.9 Template_Neff=5.700
3537
3538 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFT 763 (805)
3539 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgivilift 763 (805)
3540 ||+-++|...|-.|||.+++++.+++++.++.
3541 T Consensus 68 gp~~~~p~~~~k~v~~~~~~~~~~s~~l~~~~ 99 (147)
3542 T 5B1A_D 68 FAEMNRSTNEWKTVVGAAMFFIGFTALLLIWE 99 (147)
3543 T ss_dssp HHHHTCCCSHHHHHHHHHHHHHHHHHHHHHHH
3544 T ss_pred cccccCCCchHHHHHHHHHHHHHHHHHHHHHH
3545 Confidence 55667888889888888877776666555543
3546
3547
3548 No 78
3549 >6PY2_A HLA class II histocompatibility antigen; HLA, MHC, TCR, Gluten, IMMUNE; HET: NAG, GOL; 2.82543430029A {Homo sapiens}
3550 Probab=33.31 E-value=37 Score=31.36 Aligned_cols=9 Identities=33% Similarity=0.785 Sum_probs=5.7 Template_Neff=10.000
3551
3552 Q sp|Q9BYF1|ACE2 591 LFTWLKDQN 599 (805)
3553 Q Consensus 591 lftwlkdqn 599 (805)
3554 -++|.++..
3555 T Consensus 143 ~v~W~~~g~ 151 (254)
3556 T 6PY2_A 143 NITWLSNGH 151 (254)
3557 T ss_dssp EEEEEETTE
3558 T ss_pred EEEEEECCE
3559 Confidence 477777643
3560
3561
3562 No 79
3563 >6GJE_A Protein amnionless, Cubilin; receptor, vitamin B12, cubilin, amnionless; 2.3A {Homo sapiens}
3564 Probab=33.17 E-value=37 Score=37.81 Aligned_cols=18 Identities=28% Similarity=0.311 Sum_probs=0.0 Template_Neff=6.100
3565
3566 Q sp|Q9BYF1|ACE2 783 SIDISKGENNPGFQNTDD 800 (805)
3567 Q Consensus 783 sidiskgennpgfqntdd 800 (805)
3568 .-...+|-.||-|....+
3569 T Consensus 399 ~~~~~~gf~NP~fd~~~~ 416 (453)
3570 T 6GJE_A 399 PAGAPLGFRNPVFDVTAS 416 (453)
3571 T ss_dssp ------------------
3572 T ss_pred CCCCCCCcCCccccCCCC
3573 Confidence 556778889998877644
3574
3575
3576 No 80
3577 >6C13_A Protocadherin-15; PCDH15, LHFPL5, protocadherin, tip link; HET: MAN, BMA, NAG;{Mus musculus}
3578 Probab=32.87 E-value=38 Score=34.96 Aligned_cols=13 Identities=31% Similarity=0.317 Sum_probs=6.8 Template_Neff=10.700
3579
3580 Q sp|Q9BYF1|ACE2 693 DIIPRTEVEKAIR 705 (805)
3581 Q Consensus 693 diiprtevekair 705 (805)
3582 .++.+.++.+.+.
3583 T Consensus 508 ~i~~~~~~~~~l~ 520 (660)
3584 T 6C13_A 508 RAIDRNELFKFLD 520 (660)
3585 T ss_dssp EECCHHHHHHHHH
3586 T ss_pred eEecHHHHHHHHh
3587 Confidence 3555555555544
3588
3589
3590 No 81
3591 >5DJQ_P Cbb3-type cytochrome c oxidase subunit; oxidoreductase, cbb3-cytochrome c oxidase, Pseudomonas_stutzeri; HET: PO4, HEC, FC6, HEM; 3.2A {Pseudomonas stutzeri}
3592 Probab=32.78 E-value=38 Score=27.68 Aligned_cols=24 Identities=42% Similarity=0.845 Sum_probs=13.0 Template_Neff=3.100
3593
3594 Q sp|Q9BYF1|ACE2 748 VVMGVIVVGIVILIFTGI-----RDRKKK 771 (805)
3595 Q Consensus 748 vvmgvivvgiviliftgi-----rdrkkk 771 (805)
3596 |+.|+++||..++.|.|. ||.+||
3597 T Consensus 7 ViaGi~tVglm~~Ff~G~g~FIwkD~~k~ 35 (36)
3598 T 5DJQ_P 7 VLAGVVTVGLMVAFLAGFGYFIWRDAHKK 35 (36)
3599 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHC------
3600 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhHhhhhc
3601 Confidence 566777788877777764 555554
3602
3603
3604 No 82
3605 >1CD1_A CD1; CD1, IMMUNOLOGY, MHC, TCR, GLYCOPROTEIN; 2.67A {Mus musculus} SCOP: b.1.1.2, d.19.1.1
3606 Probab=32.51 E-value=39 Score=31.77 Aligned_cols=7 Identities=14% Similarity=0.961 Sum_probs=3.3 Template_Neff=10.400
3607
3608 Q sp|Q9BYF1|ACE2 592 FTWLKDQ 598 (805)
3609 Q Consensus 592 ftwlkdq 598 (805)
3610 .+|+++.
3611 T Consensus 217 v~W~~~g 223 (315)
3612 T 1CD1_A 217 VMWMRGD 223 (315)
3613 T ss_dssp EEEEETT
3614 T ss_pred EEEEECC
3615 Confidence 4555443
3616
3617
3618 No 83
3619 >6AT5_A HLA class I histocompatibility antigen; Human Leukocyte Antigen, Major histocompatibility; 1.5A {Homo sapiens}
3620 Probab=29.91 E-value=46 Score=33.01 Aligned_cols=8 Identities=38% Similarity=0.924 Sum_probs=4.5 Template_Neff=9.500
3621
3622 Q sp|Q9BYF1|ACE2 591 LFTWLKDQ 598 (805)
3623 Q Consensus 591 lftwlkdq 598 (805)
3624 -.+|.++.
3625 T Consensus 238 ~v~W~~~g 245 (362)
3626 T 6AT5_A 238 TLTWQRDG 245 (362)
3627 T ss_dssp EEEEEETT
3628 T ss_pred EEEEEeCC
3629 Confidence 35666653
3630
3631
3632 No 84
3633 >4JIX_A Uncharacterized protein MJ0123; Hydrolase, Metallopeptidase Zymogen, Minigluzincin; HET: GOL, SO4; 2.0A {Methanocaldococcus jannaschii}
3634 Probab=28.17 E-value=51 Score=27.66 Aligned_cols=41 Identities=20% Similarity=0.211 Sum_probs=24.4 Template_Neff=9.100
3635
3636 Q sp|Q9BYF1|ACE2 371 TAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSI 421 (805)
3637 Q Consensus 371 tahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlksi 421 (805)
3638 +--|||+|+... ..+-+..|...+..++.-...--+.|+..
3639 T Consensus 68 vi~HEl~H~~~~----------~~~H~~~f~~~~~~~~p~~~~~~~~l~~~ 108 (112)
3640 T 4JIX_A 68 IILHELIHFKIK----------SINHGIKFENELRNYFSKNECDEIELKII 108 (112)
3641 T ss_dssp HHHHHHHHHHHT----------CSSCSHHHHHHHTTTCCHHHHHHHHHHHH
3642 T ss_pred HHHHHHHHHHhh----------cccccHHHHHHHHHHcccchhhHHHHHHH
3643 Confidence 557999999762 23334567777766665544444444443
3644
3645
3646 No 85
3647 >4JIX_B Projannalysin; Hydrolase, Metallopeptidase Zymogen, Minigluzincin; HET: SO4, GOL; 2.0A {Methanocaldococcus jannaschii}
3648 Probab=28.17 E-value=51 Score=27.66 Aligned_cols=41 Identities=20% Similarity=0.211 Sum_probs=24.4 Template_Neff=9.100
3649
3650 Q sp|Q9BYF1|ACE2 371 TAHHEMGHIQYDMAYAAQPFLLRNGANEGFHEAVGEIMSLSAATPKHLKSI 421 (805)
3651 Q Consensus 371 tahhemghiqydmayaaqpfllrnganegfheavgeimslsaatpkhlksi 421 (805)
3652 +--|||+|+... ..+-+..|...+..++.-...--+.|+..
3653 T Consensus 68 vi~HEl~H~~~~----------~~~H~~~f~~~~~~~~p~~~~~~~~l~~~ 108 (112)
3654 T 4JIX_B 68 IILHELIHFKIK----------SINHGIKFENELRNYFSKNECDEIELKII 108 (112)
3655 T ss_dssp HHHHHHHHHHHT----------CSCCSHHHHHHHTTTCCHHHHHHHHHHHH
3656 T ss_pred HHHHHHHHHHhh----------cccccHHHHHHHHHHcccchhhHHHHHHH
3657 Confidence 557999999762 23334567777766665544444444443
3658
3659
3660 No 86
3661 >6IDF_E Nicastrin, Presenilin-1 (E.C.3.4.23.-), Gamma-secretase subunit; complex, MEMBRANE PROTEIN; HET: BMA, NAG, CLR, PC1;{Homo sapiens}
3662 Probab=27.63 E-value=53 Score=31.80 Aligned_cols=16 Identities=6% Similarity=0.139 Sum_probs=7.4 Template_Neff=5.100
3663
3664 Q sp|Q9BYF1|ACE2 733 PPNQPPVSIWLIVFGV 748 (805)
3665 Q Consensus 733 ppnqppvsiwlivfgv 748 (805)
3666 ||..++...|+++.|+
3667 T Consensus 9 ~~~~~~~~~~~v~i~~ 24 (129)
3668 T 6IDF_E 9 CPPPAQLHFMYVAAAA 24 (129)
3669 T ss_dssp SCCCCSSSHHHHHHTH
3670 T ss_pred CCCChhhHHHHHHHHH
3671 Confidence 3333344456555444
3672
3673
3674 No 87
3675 >6IVA_D Oxaloacetate decarboxylase beta chain (E.C.7.2.4.2); membrane protein, decarboxylase sodium pump; 4.403A {Salmonella enterica I}
3676 Probab=26.48 E-value=58 Score=29.72 Aligned_cols=27 Identities=11% Similarity=0.212 Sum_probs=12.5 Template_Neff=6.300
3677
3678 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIFTG 764 (805)
3679 Q Consensus 738 pvsiwlivfgvvmgvivvgiviliftg 764 (805)
3680 .+.+-++.+|+|+.++++.++++.+.+
3681 T Consensus 31 ~l~i~iiGm~vVF~vLilL~lvi~l~~ 57 (104)
3682 T 6IVA_D 31 GFTLMFLGMGFVLAFLFLLIFAIRGMS 57 (104)
3683 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHH
3684 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHH
3685 Confidence 344445555555555444444333333
3686
3687
3688 No 88
3689 >6IWW_B Oxaloacetate decarboxylase beta chain (E.C.7.2.4.2); membrane protein, sodium pump, decarboxylase; HET: LMT; 3.9A {Salmonella enterica subsp. enterica}
3690 Probab=26.48 E-value=58 Score=29.72 Aligned_cols=27 Identities=11% Similarity=0.212 Sum_probs=12.5 Template_Neff=6.300
3691
3692 Q sp|Q9BYF1|ACE2 738 PVSIWLIVFGVVMGVIVVGIVILIFTG 764 (805)
3693 Q Consensus 738 pvsiwlivfgvvmgvivvgiviliftg 764 (805)
3694 .+.+-++.+|+|+.++++.++++.+.+
3695 T Consensus 31 ~l~i~iiGm~vVF~vLilL~lvi~l~~ 57 (104)
3696 T 6IWW_B 31 GFTLMFLGMGFVLAFLFLLIFAIRGMS 57 (104)
3697 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHH
3698 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHH
3699 Confidence 344445555555555444444333333
3700
3701
3702 No 89
3703 >6BRJ_A Epithelial discoidin domain-containing receptor 1; Kinase, Inhibitor, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR; HET: VX6; 2.231A {Homo sapiens}
3704 Probab=25.27 E-value=63 Score=37.06 Aligned_cols=7 Identities=57% Similarity=1.545 Sum_probs=0.0 Template_Neff=8.500
3705
3706 Q sp|Q9BYF1|ACE2 602 SFVGWST 608 (805)
3707 Q Consensus 602 sfvgwst 608 (805)
3708 .||||+.
3709 T Consensus 254 ~~~~~~~ 260 (876)
3710 T 6BRJ_A 254 DYVGWSN 260 (876)
3711 T ss_dssp -------
3712 T ss_pred Ceeeeec
3713 Confidence 4555543
3714
3715
3716 No 90
3717 >3EHB_B Cytochrome c oxidase subunit 1-beta; proton pumping, water chain, electron; HET: LDA, LMT, HEA; 2.32A {Paracoccus denitrificans} SCOP: f.17.2.1, b.6.1.2
3718 Probab=25.21 E-value=63 Score=33.82 Aligned_cols=47 Identities=15% Similarity=0.255 Sum_probs=20.2 Template_Neff=6.800
3719
3720 Q sp|Q9BYF1|ACE2 725 LGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3721 Q Consensus 725 lgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3722 +|.|+..+|..+.-...+-.++.+++.+.++..+++++.-+|-|+++
3723 T Consensus 47 ~~~~~~as~~a~~i~~L~~~~l~i~~~I~v~V~~ll~~~i~ryr~~~ 93 (298)
3724 T 3EHB_B 47 MNFQPASSPLAHDQQWLDHFVLYIITAVTIFVCLLLLICIVRFNRRA 93 (298)
3725 T ss_pred cCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchhcC
3726 Confidence 55666665555544444433333322222222223334444555443
3727
3728
3729 No 91
3730 >6PY2_B HLA class II histocompatibility antigen; HLA, MHC, TCR, Gluten, IMMUNE; HET: NAG, GOL; 2.82543430029A {Homo sapiens}
3731 Probab=24.26 E-value=67 Score=30.09 Aligned_cols=11 Identities=36% Similarity=0.760 Sum_probs=0.0 Template_Neff=9.800
3732
3733 Q sp|Q9BYF1|ACE2 745 VFGVVMGVIVV 755 (805)
3734 Q Consensus 745 vfgvvmgvivv 755 (805)
3735 ++|++++++++
3736 T Consensus 235 ~~~~~~~l~~~ 245 (261)
3737 T 6PY2_B 235 IGGFVLGLIFL 245 (261)
3738 T ss_dssp -----------
3739 T ss_pred HHHHHHHHHHH
3740 Confidence 44555555444
3741
3742
3743 No 92
3744 >1Q5B_C EP-cadherin, ectodomain; CADHERIN TRANS INTERACTION ; HET: NDG, NAG, CA; 30.0A {Mus musculus} SCOP: i.20.1.1
3745 Probab=24.14 E-value=68 Score=34.98 Aligned_cols=12 Identities=25% Similarity=0.495 Sum_probs=3.1 Template_Neff=10.300
3746
3747 Q sp|Q9BYF1|ACE2 155 SLDYNERLWAWE 166 (805)
3748 Q Consensus 155 sldynerlwawe 166 (805)
3749 .+....|-|.|.
3750 T Consensus 149 ~~~r~~~~~~~~ 160 (880)
3751 T 1Q5B_C 149 GLKRKKRDWVIP 160 (880)
3752 T ss_dssp -------CCBCC
3753 T ss_pred CCccCCcceeCC
3754 Confidence 344455666654
3755
3756
3757 No 93
3758 >2JO1_A Phospholemman; FXYD1, Na,K-ATPase, Micelle, HYDROLASE REGULATOR; NMR {Homo sapiens}
3759 Probab=23.89 E-value=69 Score=29.34 Aligned_cols=30 Identities=33% Similarity=0.345 Sum_probs=11.7 Template_Neff=3.400
3760
3761 Q sp|Q9BYF1|ACE2 747 GVVMGVIVVGIVILIFTGIRDRKKKNKARS 776 (805)
3762 Q Consensus 747 gvvmgvivvgiviliftgirdrkkknkars 776 (805)
3763 |++++++...+.|+|.++-|-|-+.|+.++
3764 T Consensus 20 GLi~A~vLfi~GIliils~kckC~~~q~~~ 49 (72)
3765 T 2JO1_A 20 GLVIAGILFILGILIVLSRRCRCKFNQQQR 49 (72)
3766 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCTTTS
3767 T ss_pred HHHHHHHHHHHHHHHHHhccccccCCcCCC
3768 Confidence 444333333333333334444444444333
3769
3770
3771 No 94
3772 >2KV5_A Putative uncharacterized protein RNAI; toxin-antitoxin, bacterial, toxin; NMR {N/A}
3773 Probab=23.51 E-value=71 Score=25.42 Aligned_cols=27 Identities=22% Similarity=0.514 Sum_probs=19.0 Template_Neff=4.000
3774
3775 Q sp|Q9BYF1|ACE2 745 VFGVVMGVIVVGIVILIFTGIRD-RKKK 771 (805)
3776 Q Consensus 745 vfgvvmgvivvgiviliftgird-rkkk 771 (805)
3777 +|-.+++-|+||+++-+|+-.-| |.+|
3778 T Consensus 4 if~~IiapiivG~vv~lf~~WL~~r~~k 31 (33)
3779 T 2KV5_A 4 LMSLVIAPIFVGLVLEMISRVLDEEDDS 31 (33)
3780 T ss_dssp THHHHHHHHHHHHHHHHHHHHTTCCCCC
3781 T ss_pred HHHHhHHHHHHHHHHHHHHHHHHhcccc
3782 Confidence 45567788889999988886544 4443
3783
3784
3785 No 95
3786 >6BSD_A Epithelial discoidin domain-containing receptor 1; Kinase, Inhibitor, TRANSFERASE, TRANSFERASE-TRANSFERASE INHIBITOR; HET: 1N1; 2.606A {Homo sapiens}
3787 Probab=23.31 E-value=72 Score=36.61 Aligned_cols=7 Identities=57% Similarity=1.545 Sum_probs=3.5 Template_Neff=8.500
3788
3789 Q sp|Q9BYF1|ACE2 602 SFVGWST 608 (805)
3790 Q Consensus 602 sfvgwst 608 (805)
3791 .||||+.
3792 T Consensus 254 ~~~~~~~ 260 (876)
3793 T 6BSD_A 254 DYVGWSN 260 (876)
3794 T ss_pred Ceeeeec
3795 Confidence 4555543
3796
3797
3798 No 96
3799 >6KOE_F AA3-600 quinol oxidase subunit I; Menaquinol oxidase, Complex, Proton pumping; HET: HQO, HEA; 3.75A {Bacillus subtilis}
3800 Probab=22.61 E-value=76 Score=33.75 Aligned_cols=40 Identities=20% Similarity=0.404 Sum_probs=17.8 Template_Neff=6.100
3801
3802 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3803 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3804 ||..+.-..++++.+++.+.|+++.++++++..+|-|+++
3805 T Consensus 11 gp~a~~~~~l~~~~~~~~l~i~v~V~~l~~~~~~rYR~~~ 50 (296)
3806 T 6KOE_F 11 GPVAEQQSDLILLSIGFMLFIVGVVFVLFTIILVKYRDRK 50 (296)
3807 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchhcC
3808 Confidence 4444333333444444444443333444444556655554
3809
3810
3811 No 97
3812 >6KOB_B AA3-600 quinol oxidase subunit I; Menaquinol oxidase, Complex, Proton pumping; HET: MQ7, HEA; 3.6A {Bacillus subtilis}
3813 Probab=22.61 E-value=76 Score=33.75 Aligned_cols=40 Identities=20% Similarity=0.404 Sum_probs=15.7 Template_Neff=6.100
3814
3815 Q sp|Q9BYF1|ACE2 732 GPPNQPPVSIWLIVFGVVMGVIVVGIVILIFTGIRDRKKK 771 (805)
3816 Q Consensus 732 gppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk 771 (805)
3817 ||..+.-..++++.+++.+.|+++.++++++..+|-|+++
3818 T Consensus 11 gp~a~~~~~l~~~~~~~~l~i~v~V~~l~~~~~~rYR~~~ 50 (296)
3819 T 6KOB_B 11 GPVAEQQSDLILLSIGFMLFIVGVVFVLFTIILVKYRDRK 50 (296)
3820 T ss_dssp -----CTTHHHHHHHHHHHHHHHHHHHHTTTSSSSSSCCC
3821 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchhcC
3822 Confidence 4444333333444444444443333444444556655554
3823
3824
3825 No 98
3826 >1Q90_G Apocytochrome f, Cytochrome b6, Cytochrome; MEMBRANE PROTEIN COMPLEX, PHOTOSYNTHESIS, ELECTRON; HET: LFA, CLA, BCR, SQD, LMG, HEM, TDS; 3.1A {Chlamydomonas reinhardtii} SCOP: f.23.26.1
3827 Probab=22.36 E-value=78 Score=26.34 Aligned_cols=29 Identities=24% Similarity=0.430 Sum_probs=22.3 Template_Neff=2.400
3828
3829 Q sp|Q9BYF1|ACE2 744 IVFGVVMGVIVVGIVILIFTGIRDRKKKN 772 (805)
3830 Q Consensus 744 ivfgvvmgvivvgiviliftgirdrkkkn 772 (805)
3831 +.+|+|.|.|.|.++-|.++....-++.+
3832 T Consensus 5 lL~GIVlGli~iTlaGLfv~AY~QyrRg~ 33 (37)
3833 T 1Q90_G 5 LLCGIVLGLVPVTIAGLFVTAYLQYLRGD 33 (37)
3834 T ss_pred hHHHHHHHhHHHHHHHHHHHHHHHHHhcc
3835 Confidence 57899999999998888888765544433
3836
3837
3838 No 99
3839 >2GSM_B Cytochrome c oxidase subunit 1; transmembrane protein complex, OXIDOREDUCTASE; HET: TRD, DMU, HEA; 2.0A {Rhodobacter sphaeroides} SCOP: f.17.2.1, b.6.1.2
3840 Probab=21.90 E-value=80 Score=31.85 Aligned_cols=6 Identities=67% Similarity=1.121 Sum_probs=2.5 Template_Neff=7.600
3841
3842 Q sp|Q9BYF1|ACE2 721 SLEFLG 726 (805)
3843 Q Consensus 721 sleflg 726 (805)
3844 ||++.|
3845 T Consensus 4 ~~~~~~ 9 (262)
3846 T 2GSM_B 4 SLEIIG 9 (262)
3847 T ss_dssp -CCEEE
3848 T ss_pred ccccCC
3849 Confidence 455544
3850
3851
3852 No 100
3853 >3HB3_B Cytochrome c oxidase subunit 1-beta; Electron transfer, Proton transfer, Proton; HET: HEA, LDA, LMT; 2.25A {Paracoccus denitrificans}
3854 Probab=21.53 E-value=83 Score=32.92 Aligned_cols=47 Identities=15% Similarity=0.280 Sum_probs=18.3 Template_Neff=6.900
3855
3856 Q sp|Q9BYF1|ACE2 725 LGIQPTLGPPNQPPVSIWLIVFGVVMGVIVVGIV-ILIFTGIRDRKKKN 772 (805)
3857 Q Consensus 725 lgiqptlgppnqppvsiwlivfgvvmgvivvgiv-iliftgirdrkkkn 772 (805)
3858 ++.|+..+|-.+.-...+-+++++. .+|++++. ++++.-+|-|++++
3859 T Consensus 47 ~~~~~~aS~~a~~i~~L~~~~~~i~-~~Ifv~V~~ll~~~i~ryr~~~~ 94 (298)
3860 T 3HB3_B 47 MNFQPASSPLAHDQQWLDHFVLYII-TAVTIFVCLLLLICIVRFNRRAN 94 (298)
3861 T ss_dssp CSCSCCCSHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHSBTTTS
3862 T ss_pred CCCCCCCCHHHHHHHHHHHHHHHHH-HHHHHHHHHHHHHHHHHccccCC
3863 Confidence 3444444444443333333333332 22222222 23333355555443
3864
3865
3866 No 101
3867 >5X5V_A GD; herpes simplex virus, pseudorabies virus; 1.5A {Suid herpesvirus 1}
3868 Probab=20.11 E-value=93 Score=35.59 Aligned_cols=28 Identities=32% Similarity=0.647 Sum_probs=0.0 Template_Neff=3.400
3869
3870 Q sp|Q9BYF1|ACE2 742 WLIVFGVVMGVIVVGIVILIFTGIRDRK 769 (805)
3871 Q Consensus 742 wlivfgvvmgvivvgiviliftgirdrk 769 (805)
3872 ..+-.|+.||.|+||+.+.||..+|..|
3873 T Consensus 355 v~vgvg~~~~~~~~~~~~~~~~~~~~~~ 382 (402)
3874 T 5X5V_A 355 VIVGTGTAMGALLVGVCVYIFFRLRGAK 382 (402)
3875 T ss_dssp ----------------------------
3876 T ss_pred eehhHHHHHHHHHHHHHHHHHHHccccc
3877 Confidence 3456799999999999999998877654
3878
3879
3880
3881 Query sp|P0DTC2|SPIKE_SARS2 Spike glycoprotein OS=Severe acute respiratory syndrome coronavirus 2 OX=2697049 GN=S PE=1 SV=1
3882 Match_columns 1273
3883 No_of_seqs 1 out of 1
3884 Neff 1
3885 Searched_HMMs 82491
3886 Date Thu Nov 12 20:44:30 2020
3887 Command hhsearch -e 0.001 -i /galaxy-repl/main/files/047/416/dataset_47416633.dat -d hhdb -o /galaxy-repl/main/files/047/416/dataset_47416669.dat
3888
3889 No Hit Prob E-value P-value Score SS Cols Query HMM Template HMM
3890 1 6X29_A Spike glycoprotein; Tri 100.0 3E-269 4E-274 2251.1 0.0 1198 16-1213 1-1198(1273)
3891 2 6CS2_B Spike glycoprotein,Enve 100.0 3E-221 4E-226 1857.5 0.0 1161 31-1213 22-1182(1215)
3892 3 6Q04_B Spike glycoprotein; Cor 100.0 2E-204 2E-209 1723.9 0.0 1150 31-1224 65-1321(1359)
3893 4 5I08_C Spike glycoprotein; cor 100.0 2E-199 2E-204 1685.1 0.0 1142 30-1223 29-1293(1299)
3894 5 5X5F_B S protein; MERS-CoV, sp 100.0 6E-198 7E-203 1670.1 0.0 1163 14-1220 12-1286(1323)
3895 6 6VSJ_A Spike glycoprotein, Car 100.0 2E-195 3E-200 1649.5 0.0 1145 9-1204 22-1267(1275)
3896 7 6VSJ_C Spike glycoprotein, Car 100.0 2E-195 3E-200 1649.5 0.0 1145 9-1204 22-1267(1275)
3897 8 6OHW_A Spike surface glycoprot 100.0 7E-190 9E-195 1602.1 0.0 1144 2-1204 13-1299(1322)
3898 9 6NZK_A Spike surface glycoprot 100.0 7E-190 9E-195 1602.1 0.0 1144 2-1204 13-1299(1322)
3899 10 6M15_A Spike glycoprotein; VIR 100.0 6E-154 7E-159 1294.0 0.0 832 273-1215 216-1070(1118)
3900 11 6M15_B Spike glycoprotein; VIR 100.0 6E-154 7E-159 1294.0 0.0 832 273-1215 216-1070(1118)
3901 12 6JX7_A Feline Infectious Perit 100.0 2E-132 2E-137 1149.2 0.0 664 525-1216 674-1394(1468)
3902 13 5SZS_A Spike glycoprotein; cor 100.0 7E-131 9E-136 1128.9 0.0 662 505-1215 575-1283(1325)
3903 14 6IXB_B Spike glycoprotein; Alp 100.0 8E-129 1E-133 1101.7 0.0 647 518-1214 426-1116(1116)
3904 15 6CV0_A Spike protein; infectio 100.0 3E-125 3E-130 1068.9 0.0 651 524-1212 399-1074(1105)
3905 16 6VV5_C Spike glycoprotein; gly 100.0 2E-124 2E-129 1078.6 0.0 641 521-1213 614-1309(1356)
3906 17 6M3W_B Spike glycoprotein,Spik 100.0 2E-124 2E-129 1000.4 0.0 491 706-1196 1-491 (491)
3907 18 6U7K_C Spike glycoprotein; PED 100.0 1E-122 1E-127 1065.5 0.0 641 521-1213 629-1324(1399)
3908 19 6BFU_C Spike protein; coronavi 100.0 4E-119 4E-124 1017.5 0.0 746 267-1148 240-1022(1024)
3909 20 6B3O_B Spike glycoprotein; Cor 100.0 7E-117 9E-122 954.9 0.0 497 703-1203 45-560 (605)
3910 21 6PZ8_A S protein, G2 heavy cha 100.0 8E-112 1E-116 897.4 0.0 445 694-1140 12-470 (472)
3911 22 6PZ8_F S protein, G2 heavy cha 100.0 3.1E-74 3.8E-79 636.3 0.0 621 14-676 12-724 (726)
3912 23 7BZ5_A Spike protein S1, Heavy 100.0 3.5E-52 4.2E-57 416.5 0.0 225 319-543 1-225 (229)
3913 24 6YZ5_E Spike glycoprotein, Nan 100.0 3.5E-51 4.3E-56 405.6 0.0 205 330-534 1-205 (210)
3914 25 6YLA_E SARS-CoV-2 RBD, Heavy C 100.0 3.8E-51 4.6E-56 406.0 0.0 207 328-534 2-208 (213)
3915 26 6ZFO_A SARS-CoV-2 RBD, Nanobod 100.0 2.3E-47 2.8E-52 375.2 0.0 194 333-526 1-194 (194)
3916 27 2GHV_C Spike glycoprotein; SAR 100.0 3.9E-37 4.7E-42 305.0 0.0 197 330-527 4-200 (203)
3917 28 1WYY_A E2 Glycoprotein; membra 100.0 2.3E-36 2.8E-41 288.5 0.0 99 903-1001 3-101 (149)
3918 29 1WYY_B E2 Glycoprotein; membra 100.0 2.3E-36 2.8E-41 288.5 0.0 99 903-1001 3-101 (149)
3919 30 5X4S_A Spike glycoprotein; SAR 100.0 1.1E-34 1.4E-39 298.0 0.0 261 30-307 21-281 (285)
3920 31 5KWB_A Spike glycoprotein; Cor 100.0 1.2E-33 1.4E-38 297.9 0.0 271 316-592 1-370 (371)
3921 32 6LXT_F Spike protein S2; 2019- 99.9 2.8E-28 3.4E-33 230.5 0.0 112 910-1021 1-113 (132)
3922 33 6LXT_C 2019-nCoV S2 subunit; 2 99.9 2.8E-28 3.4E-33 230.5 0.0 112 910-1021 1-113 (132)
3923 34 6C6Z_A Spike protein, CDC2-C2 99.9 6.9E-26 8.3E-31 228.8 0.0 148 319-472 1-148 (231)
3924 35 5XGR_H Spike protein S1; MERS- 99.8 9.7E-26 1.2E-30 224.7 0.0 181 335-528 2-198 (204)
3925 36 4QZV_B Dipeptidyl peptidase 4 99.8 4.1E-25 5E-30 224.7 0.0 137 319-458 1-139 (246)
3926 37 4L3N_B S protein; beta-sheet f 99.8 2.3E-24 2.8E-29 216.3 0.0 124 334-458 3-126 (216)
3927 38 5YY5_B MERS-CoV RBD, Heavy cha 99.8 3.5E-24 4.2E-29 214.4 0.0 124 334-458 2-125 (209)
3928 39 4L72_B Dipeptidyl peptidase 4 99.8 4E-24 4.8E-29 213.4 0.0 123 335-458 1-123 (204)
3929 40 3R4D_D CEA-related cell adhesi 99.8 5.2E-24 6.3E-29 219.9 0.0 240 30-304 30-283 (288)
3930 41 4NJL_A S protein; six-helix-bu 99.8 1.2E-23 1.4E-28 199.4 0.0 122 910-1035 2-125 (131)
3931 42 6QFY_A Spike glycoprotein; sia 99.8 2.6E-23 3.2E-28 214.7 0.0 236 30-305 29-286 (288)
3932 43 4H14_A Spike glycoprotein; bet 99.8 3.5E-23 4.3E-28 214.0 0.0 235 30-304 29-285 (290)
3933 44 4MOD_B HR1 of S protein, LINKE 99.8 1.9E-22 2.2E-27 191.3 0.0 118 918-1039 2-121 (129)
3934 45 5X4R_A S protein; MERS-CoV, sp 99.7 2.2E-21 2.7E-26 204.5 0.0 263 14-306 12-337 (342)
3935 46 6J11_C Spike glycoprotein, VH 99.7 2.8E-21 3.3E-26 203.4 0.0 262 14-305 12-336 (336)
3936 47 5GYQ_A Spike glycoprotein; bat 99.7 4.2E-21 5E-26 188.9 0.0 108 332-440 2-109 (176)
3937 48 5ZVK_A Human Coronavirus MERS 99.7 7.3E-21 8.9E-26 169.6 0.0 79 910-988 2-80 (80)
3938 49 2BEZ_C E2 GLYCOPROTEIN; MEMBRA 99.6 8.5E-20 1E-24 162.0 0.0 77 914-990 1-77 (77)
3939 50 6M1V_A spike protein; 2019-nCo 99.6 2.8E-19 3.4E-24 168.2 0.0 98 917-1020 1-98 (119)
3940 51 5ZUV_A Spike glycoprotein,EK1, 99.6 1.2E-18 1.5E-23 166.1 0.0 83 914-996 2-98 (133)
3941 52 5YL9_A Spike glycoprotein; Spi 99.5 1.1E-17 1.3E-22 151.9 0.0 74 914-987 2-89 (89)
3942 53 1WDF_B E2 glycoprotein; MHV, c 99.2 2.7E-14 3.2E-19 131.3 0.0 62 919-980 1-62 (95)
3943 54 1ZVA_A E2 glycoprotein; SARS c 99.0 1.7E-13 2.1E-18 121.9 0.0 58 1144-1201 15-77 (77)
3944 55 5ZHY_D Spike glycoprotein,Spik 98.8 7.4E-12 9E-17 122.0 0.0 59 918-976 1-73 (148)
3945 56 5XJK_A Spike protein S2; VIRAL 98.7 1.4E-11 1.7E-16 107.0 0.0 62 777-838 3-64 (65)
3946 57 1ZV8_K E2 glycoprotein; SARS c 98.6 1.2E-10 1.4E-15 98.3 0.0 50 919-968 1-50 (50)
3947 58 2IEQ_B Spike glycoprotein; Hum 98.5 1.3E-10 1.5E-15 109.6 0.0 84 921-1005 7-99 (109)
3948 59 2FXP_A Spike glycoprotein; Pre 98.5 1.6E-10 2E-15 98.2 0.0 54 1158-1211 2-55 (55)
3949 60 1WDG_B E2 glycoprotein; MHV, c 98.5 2.2E-10 2.6E-15 106.1 0.0 54 919-972 1-56 (94)
3950 61 2BEQ_D E2 GLYCOPROTEIN; VIRAL 98.4 5.2E-10 6.3E-15 93.7 0.0 47 1166-1212 2-48 (48)
3951 62 2BEQ_E E2 GLYCOPROTEIN; VIRAL 98.4 5.2E-10 6.3E-15 93.7 0.0 47 1166-1212 2-48 (48)
3952 63 6LXT_F Spike protein S2; 2019- 97.7 1.4E-07 1.7E-12 91.8 0.0 45 1163-1207 87-131 (132)
3953 64 6LXT_C 2019-nCoV S2 subunit; 2 97.7 1.4E-07 1.7E-12 91.8 0.0 45 1163-1207 87-131 (132)
3954 65 4MOD_B HR1 of S protein, LINKE 97.5 4.8E-07 5.8E-12 88.0 0.0 64 1142-1205 40-123 (129)
3955 66 1ZVB_A E2 glycoprotein; SARS c 97.3 1.9E-06 2.2E-11 69.0 0.0 34 958-991 1-34 (34)
3956 67 1WDG_B E2 glycoprotein; MHV, c 97.1 5.1E-06 6.2E-11 77.9 0.0 47 1156-1202 44-94 (94)
3957 68 6M1V_A spike protein; 2019-nCo 97.0 8.6E-06 1E-10 78.8 0.0 49 1157-1205 67-115 (119)
3958 69 2BEQ_C E2 GLYCOPROTEIN; VIRAL 97.0 9.9E-06 1.2E-10 66.1 0.0 36 932-967 2-37 (38)
3959 70 5ZVM_c Human Coronavirus SARS 96.7 2.6E-05 3.2E-10 65.3 0.0 41 1165-1205 4-44 (44)
3960 71 5ZVM_b Human Coronavirus SARS 96.7 2.6E-05 3.2E-10 65.3 0.0 41 1165-1205 4-44 (44)
3961 72 2BEZ_F E2 GLYCOPROTEIN; MEMBRA 96.4 8.7E-05 1.1E-09 61.4 0.0 42 1160-1201 1-42 (42)
3962 73 6LVN_B 2019-nCoV S2 subunit; 2 96.2 0.00019 2.3E-09 58.1 0.0 35 1169-1203 2-36 (36)
3963 74 1ZV8_B E2 glycoprotein; SARS c 96.2 0.00019 2.3E-09 58.1 0.0 35 1169-1203 2-36 (36)
3964 75 6LVN_A Spike protein S2; 2019- 96.2 0.00019 2.3E-09 58.1 0.0 35 1169-1203 2-36 (36)
3965 76 5YL9_B Spike glycoprotein; Spi 91.7 0.063 7.7E-07 48.0 0.0 41 1158-1201 4-58 (59)
3966 77 5ZUV_A Spike glycoprotein,EK1, 89.5 0.16 2E-06 51.2 0.0 44 1161-1204 90-133 (133)
3967 78 6MAR_D Immunoglobulin G PGT151 71.2 3 3.7E-05 42.9 0.0 29 1199-1227 154-183 (220)
3968 79 6DCQ_D Envelope glycoprotein g 68.2 3.9 4.7E-05 45.1 0.0 49 1197-1245 146-195 (352)
3969 80 6NIJ_B PGT145 Fab heavy chain, 68.2 3.9 4.7E-05 44.9 0.0 51 1197-1247 146-197 (345)
3970 81 1WDF_B E2 glycoprotein; MHV, c 63.1 5.7 7E-05 39.1 0.0 56 1144-1202 40-95 (95)
3971 82 6GY6_C XaxA, XaxB; bacterial t 58.0 8.2 9.9E-05 41.0 0.0 24 1172-1195 232-255 (424)
3972 83 6OJ7_A Fusion glycoprotein F0; 57.5 8.5 0.0001 34.2 0.0 29 927-955 17-45 (53)
3973 84 1G2C_W TWO HEPTAD REPEATS OF H 57.5 8.5 0.0001 34.1 0.0 29 927-955 17-45 (52)
3974 85 6NYX_H Fusion glycoprotein F0; 57.3 8.6 0.0001 34.1 0.0 29 927-955 17-45 (53)
3975 86 6O40_A Fusion glycoprotein F0; 57.3 8.6 0.0001 34.1 0.0 29 927-955 17-45 (53)
3976 87 6GY8_A XaxA; bacterial toxin, 55.0 10 0.00012 39.7 0.0 22 1173-1194 233-254 (408)
3977 88 6PWU_E Envelope glycoprotein g 52.0 12 0.00014 46.6 0.0 53 1196-1248 651-704 (858)
3978 89 3EUH_B Chromosome partition pr 52.0 12 0.00014 44.2 0.0 126 858-988 125-264 (440)
3979 90 3MAW_A Fusion glycoprotein F0; 50.7 13 0.00016 44.0 0.0 76 875-955 83-158 (483)
3980 91 6EK7_A YaxA; pathogens, pore f 49.9 14 0.00017 39.3 0.0 23 1172-1194 234-256 (410)
3981 92 1SVF_C SV5 FUSION PROTEIN; PAR 49.4 14 0.00017 34.0 0.0 29 927-955 26-54 (64)
3982 93 1SVF_A SV5 FUSION PROTEIN; PAR 49.4 14 0.00017 34.0 0.0 29 927-955 26-54 (64)
3983 94 2FYZ_E Fusion glycoprotein F0; 48.5 15 0.00018 33.8 0.0 29 927-955 29-57 (63)
3984 95 2B9B_B Parainfluenza Virus 5 F 48.3 15 0.00018 43.7 0.0 76 875-955 79-154 (497)
3985 96 5YZC_B glycoprotein F2, glycop 47.2 16 0.00019 42.7 0.0 73 878-955 1-73 (419)
3986 97 1T98_B Chromosome partition pr 46.8 16 0.0002 41.3 0.0 104 858-966 125-236 (287)
3987 98 1T98_A Chromosome partition pr 46.8 16 0.0002 41.3 0.0 104 858-966 125-236 (287)
3988 99 1G5G_F FUSION PROTEIN; fusion 45.6 18 0.00021 42.9 0.0 76 875-955 83-158 (481)
3989 100 5EVM_F Fusion glycoprotein F0; 45.4 18 0.00022 43.4 0.0 76 875-955 107-182 (529)
3990 101 6T3F_F Fusion glycoprotein F0, 42.9 21 0.00025 42.7 0.0 76 875-955 85-160 (502)
3991 102 3N27_B Fusion glycoprotein F0, 42.7 21 0.00025 34.6 0.0 28 927-954 18-45 (80)
3992 103 1ZTM_C Fusion glycoprotein; fu 42.5 21 0.00026 42.4 0.0 75 876-955 90-164 (490)
3993 104 4GIP_D Fusion glycoprotein F2, 42.0 22 0.00026 41.5 0.0 72 878-955 1-73 (409)
3994 105 6H2E_Q AhlB; Tripartite pore-f 41.7 22 0.00027 35.5 0.0 23 1173-1195 128-150 (274)
3995 106 5IJO_G Nuclear pore complex pr 40.4 24 0.00029 42.7 0.0 55 1133-1189 239-293 (599)
3996 107 1WP7_A fusion protein; Nipah V 40.3 24 0.00029 34.8 0.0 28 927-954 18-45 (89)
3997 108 1WP8_C fusion; Hendra Virus, F 39.6 25 0.00031 34.6 0.0 28 927-954 18-45 (89)
3998 109 6R1J_J AhlB; Tripartite pore-f 39.2 26 0.00031 34.8 0.0 24 1172-1195 127-150 (272)
3999 110 6C14_A Protocadherin-15, LHFPL 38.6 27 0.00032 35.4 0.0 26 1108-1133 82-109 (337)
4000 111 5EJB_D Fusion glycoprotein F0; 38.0 28 0.00034 41.7 0.0 76 875-955 82-157 (501)
4001 112 2M8R_A Syntaxin-1A; syntaxin, 36.7 30 0.00036 29.7 0.0 12 1211-1222 84-95 (109)
4002 113 3HD7_B Vesicle-associated memb 36.7 30 0.00036 29.7 0.0 12 1211-1222 84-95 (109)
4003 114 5C3L_B Nucleoporin Nup54, MGC8 34.3 35 0.00042 32.1 0.0 57 1131-1189 6-62 (142)
4004 115 5G6U_A LANGERIN; CARBOHYDRATE 33.0 38 0.00046 33.5 0.0 42 1038-1090 123-164 (261)
4005 116 3IPD_E Vesicle-associated memb 26.9 56 0.00068 28.7 0.0 9 1212-1220 68-76 (91)
4006 117 3HD7_A Vesicle-associated memb 26.9 56 0.00068 28.7 0.0 9 1212-1220 68-76 (91)
4007 118 6BP2_B Envelope Glycoprotein G 24.9 64 0.00078 35.3 0.0 40 925-964 122-161 (202)
4008 119 6QD8_D Light chain, Virion spi 23.5 72 0.00087 33.9 0.0 34 931-964 61-94 (168)
4009 120 4NJL_A S protein; six-helix-bu 22.6 76 0.00092 33.2 0.0 27 1178-1204 104-130 (131)
4010 121 4LWS_B Uncharacterized protein 22.2 79 0.00095 26.3 0.0 32 955-986 54-85 (103)
4011 122 2NRJ_A Hbl B protein; Enteroto 21.9 80 0.00097 32.4 0.0 15 1205-1219 194-208 (346)
4012 123 2N2A_B Receptor tyrosine-prote 21.7 81 0.00099 26.9 0.0 23 1206-1228 1-23 (58)
4013 124 6F5U_B Envelope glycoprotein,G 21.4 83 0.001 33.1 0.0 38 927-964 57-94 (168)
4014 125 5F1B_B GP1, GP2, Niemann-Pick 21.4 84 0.001 31.9 0.0 37 929-965 52-88 (130)
4015 126 6HS4_B Envelope glycoprotein,E 21.3 84 0.001 33.1 0.0 40 925-964 55-94 (168)
4016 127 2KG7_A Uncharacterized protein 21.1 85 0.001 25.8 0.0 66 923-988 14-80 (97)
4017 128 6W08_B NSP15 endoribnuclease; 20.9 87 0.0011 32.8 0.0 55 1139-1193 122-184 (359)
4018 129 3OGI_C Putative ESAT-6-like pr 20.4 90 0.0011 26.8 0.0 66 921-986 11-77 (101)
4019 130 5HJ3_L Envelope glycoprotein, 20.1 93 0.0011 31.8 0.0 35 930-964 60-94 (136)
4020 131 6RX1_A Syncytin-1; HUMAN PLACE 20.0 93 0.0011 31.0 0.0 53 908-964 12-64 (108)
4021
4022 No 1
4023 >6X29_A Spike glycoprotein; Trimer, VIRAL PROTEIN; 2.7A {Severe acute respiratory syndrome coronavirus 2}
4024 Probab=100.00 E-value=2.9e-269 Score=2251.14 Aligned_cols=1198 Identities=99% Similarity=1.476 Sum_probs=961.9 Template_Neff=3.900
4025
4026 Q sp|P0DTC2|SPIK 16 VNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFAST 95 (1273)
4027 Q Consensus 16 vnlttrtqlppaytnsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndgvyfast 95 (1273)
4028 |||||||||||+||.+..+|+||||..++|++.+.+|+||+|+.+++++++|||++|++....+++++.||+||+|+...
4029 T Consensus 1 ~~~~~~~~~~~~~~~~~~~g~yYpd~~~~sn~t~l~qglfp~~~s~~~~y~~~~~~gt~~~~~y~~~~~~F~dGifv~v~ 80 (1273)
4030 T 6X29_A 1 VNLTTRTQLPPAYTNSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFAST 80 (1273)
4031 T ss_dssp -----------CEEECCSCCCBCCSSEECCSEEEEEEEEECCTTCEEECCCCCC----------CCCCEECTTCEEEEEE
4032 T ss_pred CCcccccCCCCCcccccceeeEeeCCeeEeecccccccccCCCCCCceEEeeEEeecCCcccccCCCCcccCCeEEEEee
4033 Confidence 69999999999999999999999999999999999999999999999999999999999999999999999999999999
4034
4035
4036 Q sp|P0DTC2|SPIK 96 EKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPF 175 (1273)
4037 Q Consensus 96 eksniirgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpf 175 (1273)
4038 +++|..++|+||+|.+.++++++|+++.+.+.|.+|.|++|..|++.++++.+|.+|+|++++.|..++||+|+|..|+|
4039 T Consensus 81 ~~~n~~p~~~fGstf~n~s~tvvI~P~~~~~~it~C~~~vC~~p~~~~~~~~g~~~~~~~~~~~~~~~~nc~f~~~~~nf 160 (1273)
4040 T 6X29_A 81 EKSNIIRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPF 160 (1273)
4041 T ss_dssp ESSCCEEEEEEESSCSSSSCCCEEEECSSCEEEECCCCCCCSSCCEEC---------------------CCCCEEEC---
4042 T ss_pred ecccCcceEeEEeccCCCcEEEEEeCCCcceEEEEEEEEecCCCeeEEEeecCCceeeeeehhhhccCCCceEEEecCCc
4043 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4044
4045
4046 Q sp|P0DTC2|SPIK 176 LMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSS 255 (1273)
4047 Q Consensus 176 lmdlegkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdss 255 (1273)
4048 .||.+.++|+|...++|+|++.||+|.+|..+++++..+.+|+|+..+.|..++|+|+||+|+|.++.+.|++.+|++.+
4049 T Consensus 161 t~d~~~~~~~~~~~~~~~F~~~dG~f~iY~~~~~~~~~~~~~~~~~~~~yy~~~p~g~n~~~~~~~~~~~~~~~~~~~~~ 240 (1273)
4050 T 6X29_A 161 LMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSS 240 (1273)
4051 T ss_dssp ----------CCEEEEEEEEEETTEEEEEEEEEECCCSSSCCSSCCCBEEEEEEECCCCCSEEEEEEEEC----------
4052 T ss_pred eeccccCccceeeeEeEEEEecCCeEEEEEeCCCCcccccCCccccccchhhcCCCCCccccceeEEEeeeecCCCCCCC
4053 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999889
4054
4055
4056 Q sp|P0DTC2|SPIK 256 SGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNL 335 (1273)
4057 Q Consensus 256 sgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnl 335 (1273)
4058 ++|+.+.++|||+||+||+|||+|++||.||+||||+.||++|.||..+||++++|+|++|+||+||...++|+++++..
4059 T Consensus 241 ~~~~~~~~~~yV~~L~~r~yLl~fd~nG~It~AvDCa~~~~sEL~Cst~SF~p~tGVY~lS~yraqP~~~V~~~~~~~~~ 320 (1273)
4060 T 6X29_A 241 SGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNL 320 (1273)
4061 T ss_dssp -------CCEEECCCEEEEEEEEECTTSCEEEECCTTSCHHHHHHHHHTCSSCCSEEEEEEEEECCCCCCCEECCCCCCB
4062 T ss_pred cccceeeeEEEEEeccceeEEEeecCCCeEeEEEecccCcchhceeEecceecCCcEEeccCeEEEeceEEEEcCCCCCC
4063 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4064
4065
4066 Q sp|P0DTC2|SPIK 336 CPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQT 415 (1273)
4067 Q Consensus 336 cpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqt 415 (1273)
4068 |+|.+++++.++.++|.|.|++++||..|+++|++..++++|+||||+|.||.++||..|++|.|.|..++.++++||++
4069 T Consensus 321 C~~~~~~~~~~~Psp~~w~R~~fsNCnfn~s~Lls~~~~~~f~C~~ispskL~~mCfssvtiD~F~ip~~~~~~l~~g~~ 400 (1273)
4070 T 6X29_A 321 CPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVCPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQT 400 (1273)
4071 T ss_dssp CCCHHHHTCSSCCCGGGCEEEEECSSBCCHHHHHHCSCCSEEEESSSCGGGGTTCCCSEEEEEEEEECGGGGTTCSTTCC
4072 T ss_pred CChhHHhcCCCCCCcceeEEEEEecCCCcHHHHhhccccceeEEeCCCHHHhcccccCeeEEEEEEecccceeecCCCCC
4073 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4074
4075
4076 Q sp|P0DTC2|SPIK 416 GKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSY 495 (1273)
4077 Q Consensus 416 gkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsy 495 (1273)
4078 |.|++||||+|+||+||+++|+.++++..+.++|||++|.+++++++|||||+++|+||.+.++|+...|.+|++|+..+
4079 T Consensus 401 g~i~~yNYkl~~~~~~C~l~~~~~~~~~~~t~~y~~~~~~~~~~~~~~~~~~~~~~~y~~~~~~C~~~~~~~C~~pl~~~ 480 (1273)
4080 T 6X29_A 401 GKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSY 480 (1273)
4081 T ss_dssp STTTTTTCCCCTTCCEEEEEEECTTTTCC--CBCCCEEC-------CTTCCCC--------------------CCSCEEC
4082 T ss_pred cHHHhcCcCCCCCCCCeEEEEEeCCcccCCcccHHHHHHhcccCCCCcccCCCchhhhcCCCCCCCCCCcccceeccccc
4083 Confidence 99999999999999999999999999998999999999999999999999999999999999999976799999999999
4084
4085
4086 Q sp|P0DTC2|SPIK 496 GFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDA 575 (1273)
4087 Q Consensus 496 gfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttda 575 (1273)
4088 ++....|++++.+++++++++....|++|||.+..++++.++||++|..|.||+||++++|..+..+|.||.++.|+..+
4089 T Consensus 481 ~~~~~~g~~~~c~~lv~IT~~~t~~~~~Vc~~~~~snI~LnvCVdYNIYGiTGqGVItntn~t~~~~q~~gl~~~g~s~g 560 (1273)
4090 T 6X29_A 481 GFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDA 560 (1273)
4091 T ss_dssp CBCTTC-CTTSCEEEEEEEEECCSSCCCCCCSCCCCCCCCSSEECCEETTEECCEEEEECCCCCCTTCCEEECTTSCEEE
4092 T ss_pred ceecCCcccceeeEEEEEEEecCCCCCcccCCcCCceeEeceEEeeEeCCceeEEEEEecCCCCccchhcceecCCCcce
4093 Confidence 88888999999999999999999999999999999999999999999999999999999999999999999999999999
4094
4095
4096 Q sp|P0DTC2|SPIK 576 VRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEH 655 (1273)
4097 Q Consensus 576 vrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaeh 655 (1273)
4098 +|++.++++..|+||..+.++|+..|+|+++|+|+||..+||++++.++++.+++|.|++++++++.||||+||++||.+
4099 T Consensus 561 FKn~ttG~~YsV~PC~~~~QsVVy~g~~~s~q~AgL~tSinCt~v~~~~~s~~~t~~fy~~s~~~~~~~T~~gcv~na~~ 640 (1273)
4100 T 6X29_A 561 VRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEH 640 (1273)
4101 T ss_dssp EECSSSCCEEEEECCCEEEEEEEECCTTTCSCCEEEEETCCTTCC--------------------CEEECSSEEEESCEE
4102 T ss_pred EECCCCCCEEEEEeCcccceEEEcCCCCCcceEEEEEeccCCCCCcceeeccccCCeeEEEeCCCCceeeceeEeeccee
4103 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4104
4105
4106 Q sp|P0DTC2|SPIK 656 VNNSYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTS 735 (1273)
4107 Q Consensus 656 vnnsyecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtkts 735 (1273)
4108 .++..+|+.|+|.|||+.+.+...+++..+.+....+..|+|.+..+..++.+...|.||+||||+|++|.++++|.|.+
4109 T Consensus 641 ~t~~~~C~~Pvg~giC~d~~~~~~~~~s~~~~~~~~l~~~~~p~~~~~~~~~~~~~i~IP~nFtlsvt~EyiQt~~~kVs 720 (1273)
4110 T 6X29_A 641 VNNSYECDIPIGAGICASYQTQTNSPGSASSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTS 720 (1273)
4111 T ss_dssp CSSCCCCSEEEETTEEEEEEC------------CCEEEEEECCCSCEEECCCCTTEEEEEEEEEEEEEEEEEECCCCCEE
4112 T ss_pred cCCCCcCCCCceEEEeecCCccCCCCCccccccceeEEeeeccCCccccccccceEEEccCCeEEEEEEEEeeecCCceE
4113 Confidence 99999999999999999999843333323345667888999988887888899999999999999999999999999999
4114
4115
4116 Q sp|P0DTC2|SPIK 736 VDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKR 815 (1273)
4117 Q Consensus 736 vdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskr 815 (1273)
4118 |||.+|+|||+.+|.+||.|||+||..+|+||.|.+..+|.+..+++..+++.++++.+.+|+||||+.+||.+++|++|
4119 T Consensus 721 IDC~~YVC~~~~rC~~LL~QYgsfC~~I~~aL~~~a~led~~~~~~~s~~~~~~~~~~~~~~~~fN~s~llp~~~~~~~R 800 (1273)
4120 T 6X29_A 721 VDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKR 800 (1273)
4121 T ss_dssp ECHHHHHSTTCHHHHHHHGGGCTTHHHHHHHHHHHHHHHHHHHHHHHTTSSSEEECCSSCCSTTCCCTTTSBCTTSSSCC
4122 T ss_pred EecchhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHhcHHHHHHHHHhhHHhcCCCcccCCCccccccCCCCCCCCCc
4123 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4124
4125
4126 Q sp|P0DTC2|SPIK 816 SFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQ 895 (1273)
4127 Q Consensus 816 sfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalq 895 (1273)
4128 |+||||||+||+.+|.|+.+.|.+|.++..+|||+|||.|||+.||||++++||++.||++|++|....|||||+++|..
4129 T Consensus 801 SaIEDLLF~KV~t~glG~~~~Yk~Ct~g~~i~DL~CAQyyNGimVLPpv~d~~~~amYTasL~g~m~~gg~T~G~tsaaa 880 (1273)
4130 T 6X29_A 801 SFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQ 880 (1273)
4131 T ss_dssp BHHHHHHSSSCC--------------------------CCSSEEECCCSSCHHHHHHHHHHHHHHHHHHTTHHHHSSCCC
4132 T ss_pred cHHHHHhcCceEeCCCChhHhhHHccCCccHHHHhcccccCcEEEeCCCCCHHHHHHHHHHHHHHHHhcccccCcchhcc
4133 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4134
4135
4136 Q sp|P0DTC2|SPIK 896 IPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISS 975 (1273)
4137 Q Consensus 896 ipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaiss 975 (1273)
4138 |||||||.||+||+|+||+||.||||+|||.||.||+.||+.++.|++||.|+|||||++++||++|++||+.|||||||
4139 T Consensus 881 iPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~i~~g~~tts~AL~kiQ~VVN~~~~aL~~L~~QL~nnFgAISS 960 (1273)
4140 T 6X29_A 881 IPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISS 960 (1273)
4141 T ss_dssp CCHHHHHHHHHHTTTCCTHHHHTTHHHHHHHHHHHHHHHHHHHSSCGGGGHHHHHHHHHHHHHHHHHGGGGGCCTTSSCS
4142 T ss_pred chhHHHHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHH
4143 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4144
4145
4146 Q sp|P0DTC2|SPIK 976 VLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQS 1055 (1273)
4147 Q Consensus 976 vlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqs 1055 (1273)
4148 .++||++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..||+|||..||+|.+|||.|.|++|+||.
4149 T Consensus 961 SI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qKINECVKsQS~R~gFCGnG~Hi~S~~q~ 1040 (1273)
4150 T 6X29_A 961 VLNDILSRLCPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQS 1040 (1273)
4151 T ss_dssp CHHHHTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTSSCCCSTTSSSSSEEEECCEEE
4152 T ss_pred HHHHHHHhhchhHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccCcccCcCCCCeeEEecccc
4153 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4154
4155
4156 Q sp|P0DTC2|SPIK 1056 APHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNN 1135 (1273)
4157 Q Consensus 1056 aphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnn 1135 (1273)
4158 ||+|++|+|++|+|.+.++.+++|.+|+++++..|++|+|+.|+++|++|.|++|||..||.+|..+...|||....+|+
4159 T Consensus 1041 AP~Gi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~g~~~~~~~~~~~T~r~~y~P~~~t~~d~v~i~sC~V~y~~vn~ 1120 (1273)
4160 T 6X29_A 1041 APHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNN 1120 (1273)
4161 T ss_dssp ETTEEEEEEEEEEEEEEEEEECBSCEESSSCEEEESSSEEEESSSSEEEECSSSCCCBCCBTTTEEECSCTTTSTTCEEC
4162 T ss_pred CCCeEEEEEEEecccceEEEEEeceEeeCCceeeecceEEEEcCCEEEEcccccccCccCCCCceEEeccceeEEEEecc
4163 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4164
4165
4166 Q sp|P0DTC2|SPIK 1136 TVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
4167 Q Consensus 1136 tvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikwp 1213 (1273)
4168 ++.+|++|++..|+|||+|||||||+|+.++++++.+|++++|++.||++|+|+.|+||+++|||++|++||+|-+++
4169 T Consensus 1121 t~~~~~~pd~~df~~el~~~~~N~t~p~~~~~~~~~~N~T~LNLt~EI~~Lq~~I~~LN~slIDLe~Ln~~e~y~~~~ 1198 (1273)
4170 T 6X29_A 1121 TVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQGSGYI 1198 (1273)
4171 T ss_dssp CCBCSHHHHHHC------------------------------------------------------------------
4172 T ss_pred cccCCCCCCCCCHHHHHHHHccCCCCCCCCCCccccccccccchHHHHHHHHHHHHHHHHhcccHHHhcceeeeccCC
4173 Confidence 999999999999999999999999999999999999999999999999999999999999999999999999998764
4174
4175
4176 No 2
4177 >6CS2_B Spike glycoprotein,Envelope glycoprotein, Angiotensin-converting enzyme; membrane fusion, glycoprotein, receptor binding; HET: BMA, MAN, NAG;{Human SARS coronavirus}
4178 Probab=100.00 E-value=3.2e-221 Score=1857.50 Aligned_cols=1161 Identities=77% Similarity=1.263 Sum_probs=1101.0 Template_Neff=4.100
4179
4180 Q sp|P0DTC2|SPIK 31 SFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTTL 110 (1273)
4181 Q Consensus 31 sftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgttl 110 (1273)
4182 +-.+|+||||..++++...-+|++|.++-++++-+|+. -.-+.+++.||+||+++...+++|.-++|+||+|.
4183 T Consensus 22 ~~~~g~yYPd~~~~sN~t~L~qglfp~~gs~~~~~~~~-------~~~y~~~~~~F~dGifv~v~~~~n~~~a~~fGsTF 94 (1215)
4184 T 6CS2_B 22 SSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHTI-------NHTFGNPVIPFKDGIYFAATEKSNVVRGWVFGSTM 94 (1215)
4185 T ss_pred cccceeEecCCeeeccceeeeeCccCCCCCCCccCCcc-------hhhcCCCccccCCcEEEEeeEecCCCCceeeeecc
4186 Confidence 45689999999999999999999999999999987776 34577889999999999999999998899999999
4187
4188
4189 Q sp|P0DTC2|SPIK 111 DSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLR 190 (1273)
4190 Q Consensus 111 dsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlr 190 (1273)
4191 +..+++++|+++-+...|.+|.|..|..|...+++.-.| -.+++.|..+.||+|.|.|+.|-+|...+-.+....+
4192 T Consensus 95 ~N~s~tvVI~P~~~~~~it~C~~~vC~~p~~~~~p~~gn----~~~~~~~~~~~nc~f~~~~~nfT~d~~~~~~~~~~r~ 170 (1215)
4193 T 6CS2_B 95 NNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGT----QTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHLR 170 (1215)
4194 T ss_pred cCCceEEEEcCCCCcceeeEeEEEeCCCCceeEcCCCCC----cccccceeecCCceEEEcccccccccccceeeeeEEE
4195 Confidence 999999999999999999999999999999988874443 4678889999999999999999999888888888899
4196
4197
4198 Q sp|P0DTC2|SPIK 191 EFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
4199 Q Consensus 191 efvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
4200 +|+|++.||+|-+|-.+.+.+..+.+|.|...|.|..-+|..++|+.|..++ -.|| ++ .+.|+...++|||.+|
4201 T Consensus 171 ~f~F~~~~G~fy~Y~a~~~~~~f~~~~~~~~~l~yy~vip~~~~~~~~~~~~-~~~~--~~---~~~~~~~~~~~yv~~L 244 (1215)
4202 T 6CS2_B 171 EFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAIL-TAFS--PA---QDIWGTSAAAYFVGYL 244 (1215)
4203 T ss_pred EEEEEecCCeEEEEeecCCCcccccCCCCcccceeeEeeceecccccceEEe-eecC--CC---CCcccccceEEEEeec
4204 Confidence 9999999999999988877777899999999999999999999999998872 2233 22 5677888999999999
4205
4206
4207 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASV 350 (1273)
4208 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasv 350 (1273)
4209 .+|+++|.|..||+|+|++||+-+|.+|-+|.-.+|....|.|..++++++|.-...|.......|+|.+++++.++.++
4210 T Consensus 245 ~~~~~lLayf~NGti~dvIdC~~sp~~~LaCqy~T~nfsdGvYp~s~~~vk~~fiVyr~~~~~~~C~~~~~~~~~~~Psp 324 (1215)
4211 T 6CS2_B 245 KPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSFEIDKGIYQTSNFRVVPSGDVVRFPNITNLCPFGEVFNATKFPSV 324 (1215)
4212 T ss_pred eeceeehHHhcCCeEEEEEECCCCcccceeceeceeccCCCeeeccceEeeceEEEEECCCCCCCCCHHHHhhCCCCCCc
4213 Confidence 99999999999999999999999999999999999999999999999999999999999988899999999999999999
4214
4215
4216 Q sp|P0DTC2|SPIK 351 YAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFT 430 (1273)
4217 Q Consensus 351 yawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddft 430 (1273)
4218 |.|.|+.++||..|+++|++..++++|+||||||.||.+.||..|++|.|.|..+..++++||++|.|++||||+|+||+
4219 T Consensus 325 ~~w~R~~fsnCnfn~s~Lls~~~~~~f~C~gIspskLa~mCfsSvtiD~F~ip~s~~~~l~~g~~g~i~~~NYkl~~~~~ 404 (1215)
4220 T 6CS2_B 325 YAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQIAPGQTGVIADYNYKLPDDFM 404 (1215)
4221 T ss_pred cceeEeEEecCCCCHHHHHhcceeeeeEeeCCCHHHHcccccCeeeEEEeeccccchhhcCCCCCchHHhcccCCCCCCC
4222 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4223
4224
4225 Q sp|P0DTC2|SPIK 431 GCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRV 510 (1273)
4226 Q Consensus 431 gcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfplqsygfqptngvgyqpyrv 510 (1273)
4227 ||+++|+-.+++..+..++|+.++-.|+..++|+++|.+.--+.-...+|. ..|-.|..++..|.+...-|+|++++++
4228 T Consensus 405 ~C~l~~~~~~~~vn~t~~~n~~~~~~r~~~~~~~~~d~~~CPf~~~~s~C~-~~~~~~~~~i~~~~~~~~~g~~~~~~g~ 483 (1215)
4229 T 6CS2_B 405 GCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCT-PPALNCYWPLNDYGFYTTTGIGYQPYRV 483 (1215)
4230 T ss_pred ceEEEEEcCccceeccCCCCcccccccccceeecCCCCCCCCCCCCCCCCC-CCCCCCCcccccccceeeccccceeeEE
4231 Confidence 999999988888776667777766666666889999888744444467884 3666777788888765567999999999
4232
4233
4234 Q sp|P0DTC2|SPIK 511 VVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPC 590 (1273)
4235 Q Consensus 511 vvlsfellhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpc 590 (1273)
4236 ++++++....|++|||+|..+.++.+.||++|+.|.||+||++|+|..+..+|.|+.|..+-..++||+.|+++..|+||
4237 T Consensus 484 lvis~k~~~~p~tVCg~~~~T~l~ldvCV~YnIYGiTGtGVi~~sn~t~~sgqsf~~ds~GfL~gfKn~ttG~iYsI~PC 563 (1215)
4238 T 6CS2_B 484 VVLSFELLNAPATVCGPKLSTDLIKNQCVNFNFNGLTGTGVLTPSSKRFQPFQQFGRDVSDFTDSVRDPKTSEILDISPC 563 (1215)
4239 T ss_pred EEEEEEEcCCCCcccCCcCccceeeceeEeEEeCCceeeEEEEecCcEecCCeeeEEeCCcceeEEEeCCCCCEEEEeeC
4240 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4241
4242
4243 Q sp|P0DTC2|SPIK 591 SFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGI 670 (1273)
4244 Q Consensus 591 sfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipigagi 670 (1273)
4245 .++.|||+.+|.++|+..|+||..++|+++....+..+.+|.|+.++++.+.|||-+||++||++.+...+|++|+|.|+
4246 T Consensus 564 ~s~~VSVVy~g~~sS~~~alLf~~v~C~~v~~~~~~~~~~p~~~~~s~~~~~fdT~~GCv~na~n~~~v~~C~lplG~Gl 643 (1215)
4247 T 6CS2_B 564 AFGGVSVITPGTNASSEVAVLYQDVNCTDVSTAIHADQLTPAWRIYSTGNNVFQTQAGCLIGAEHVDTSYECDIPIGAGI 643 (1215)
4248 T ss_pred eecceEEEEcCCccCCCcceeccccccccccccccceeecCceEEeeCCCCCcccccceeecccCCCcccccCcccccee
4249 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4250
4251
4252 Q sp|P0DTC2|SPIK 671 CASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECS 750 (1273)
4253 Q Consensus 671 casyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecs 750 (1273)
4254 |+.+.+ .++.|+....++..|+++++....++.+...|.||+||||+|++|-++++|.|.+|||.+|+||++.+|.
4255 T Consensus 644 C~d~~~----~~~~~~~~~~~~~~y~~p~~~~s~~~~~~~~i~IP~nft~~v~~Eyiq~~~~kv~idC~~YVC~~~~~C~ 719 (1215)
4256 T 6CS2_B 644 CASYHT----VSLLRSTSQKSIVAYTMSLGADSSIAYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECA 719 (1215)
4257 T ss_pred ecCCCc----eeeccCCCceeeeeeecCCCCCCCCCceeeEEEccCCeEEEEEEEEeeecCCCeEEechhhccCCCHHHH
4258 Confidence 999988 3333335566778999998765578888999999999999999999999999999999999999999999
4259
4260
4261 Q sp|P0DTC2|SPIK 751 NLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLAD 830 (1273)
4262 Q Consensus 751 nlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtlad 830 (1273)
4263 +||.|||+||..+|+||.+.+..+|.+..+++...++-++.|-+..||||||+.+||.++++++||+||||||+||..+|
4264 T Consensus 720 ~lL~qYgs~C~~I~~al~~~~~l~d~~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l~~~~~~~~RS~iEDLLF~KV~t~g 799 (1215)
4265 T 6CS2_B 720 NLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQVKQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLAD 799 (1215)
4266 T ss_pred HHHHHHHHHHHHHHHHHHHHHhHHhHHHHHHHHhcccCCCCCcccccCCccchhcCCCCCCCCCccHHHHHHcCeeeeCC
4267 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4268
4269
4270 Q sp|P0DTC2|SPIK 831 AGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIG 910 (1273)
4271 Q Consensus 831 agfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngig 910 (1273)
4272 .|+.+.|.+|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||||+|+|..|||||||.||+||+|
4273 T Consensus 800 ~g~~~~Y~~C~~g~~i~DL~CaQ~ynGi~VLP~v~~~~~~a~YT~sl~g~ma~gg~T~g~~sa~aiPFa~~vq~RlN~v~ 879 (1215)
4274 T 6CS2_B 800 AGFMKQYGECLGDINARDLICAQKFNGLTVLPPLLTDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIG 879 (1215)
4275 T ss_pred CCchhhHhhccCCccHHHHhcccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhccccccccccccccHHHHHHHHhchhh
4276 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4277
4278
4279 Q sp|P0DTC2|SPIK 911 VTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAE 990 (1273)
4280 Q Consensus 911 vtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveae 990 (1273)
4281 +||+||.||||+|||.||.||+.||+.++.+++||.|+||||||+++||++|++||+.|||||||.++||++|||++||+
4282 T Consensus 880 l~~~vL~~NQk~iA~sFN~A~~~i~~g~~t~~~Al~kiQ~VVN~~~~aL~~L~~qL~~nFgAISssi~dIy~RLd~leAd 959 (1215)
4283 T 6CS2_B 880 VTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAE 959 (1215)
4284 T ss_pred ccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHH
4285 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4286
4287
4288 Q sp|P0DTC2|SPIK 991 VQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPA 1070 (1273)
4289 Q Consensus 991 vqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpa 1070 (1273)
4290 +||||||+|||.+|++||+|+|+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||+|++|+|.+|+|.
4291 T Consensus 960 aQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~lA~qKinECVksQS~R~gFCGnG~Hi~S~~q~AP~Gi~F~H~~~~Pt 1039 (1215)
4292 T 6CS2_B 960 VQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPS 1039 (1215)
4293 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccCcCCCCCCeeeEeecccCCCeEEEEEEeeccc
4294 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4295
4296
4297 Q sp|P0DTC2|SPIK 1071 QEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKE 1150 (1273)
4298 Q Consensus 1071 qeknfttapaichdgkahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfke 1150 (1273)
4299 +.++.+++|.+|+++++..|++|+|+.|++.|++|.|++|||..||.+|...-..|||....+|+++.+|++|++..|+|
4300 T Consensus 1040 ~~~~v~a~~GlC~~~~~~~~~~g~f~~~~~~~~~T~r~~y~P~~~t~~d~v~i~sC~V~y~nvn~~~~~~~~p~~~df~~ 1119 (1215)
4301 T 6CS2_B 1040 QERNFTTAPAICHEGKAYFPREGVFVFNGTSWFITQRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKE 1119 (1215)
4302 T ss_pred ceeEEEEEceeeeCCCceeecceEEEEcCcEEEEeccccccCCCCChhceEEeecCceeEEeecCCCCCCCCCCCCCHHH
4303 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4304
4305
4306 Q sp|P0DTC2|SPIK 1151 ELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
4307 Q Consensus 1151 eldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikwp 1213 (1273)
4308 ||++|+||||+|+.+++++..+|++++|++.||++|+|+.|+||+++|||++|++||+|-+|+
4309 T Consensus 1120 el~~~~~N~t~p~~~~~~~~~~N~t~LnLt~EI~~L~~~i~~LN~s~IDLe~L~~~e~ya~~~ 1182 (1215)
4310 T 6CS2_B 1120 ELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQGSGYI 1182 (1215)
4311 T ss_pred HHHHHhcCCCCCCCCCCChhhccccccchHHHHHHHHHHHHHHHhcCcCHHHhcceeHhhcCC
4312 Confidence 999999999999999999999999999999999999999999999999999999999998875
4313
4314
4315 No 3
4316 >6Q04_B Spike glycoprotein; Coronavirus, spike glycoprotein, MERS-CoV, membrane; HET: MAN, SIA, NAG, FOL, BMA; 2.5A {Human betacoronavirus 2c EMC/2012}
4317 Probab=100.00 E-value=1.8e-204 Score=1723.92 Aligned_cols=1150 Identities=31% Similarity=0.496 Sum_probs=897.1 Template_Neff=3.700
4318
4319 Q sp|P0DTC2|SPIK 31 SFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRFDNPVLPFNDGVYFASTEKSNII 101 (1273)
4320 Q Consensus 31 sftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krfdnpvlpfndgvyfasteksnii 101 (1273)
4321 +-.+|+||||..++++..+-.|++|.+.-++.+-.- ++|++. + -.++.+..||+||+++...+.+|--
4322 T Consensus 65 s~~~G~yYPd~rvysN~TlL~qglfP~~gs~~~~y~---~~~t~~~s~~~~~~~~~~y~~~~~~F~dGifvkv~~~~n~t 141 (1359)
4323 T 6Q04_B 65 SKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANYSQDVKQFANGFVVRIGAAANST 141 (1359)
4324 T ss_dssp GGTTTCBCCTTCEECSEEEEEEEEECCTTCCCEEEC---CEECCEETTEECSEEECSCTTCCEECTTCEEEEESTTTTSE
4325 T ss_pred ccCceeEeeCCeeEeeeeeeeeceecCCCCcceEEE---EEecCCCCCCCcceeeeccCCChhhccCeEEEEEeeeecCC
4326 Confidence 346899999999999999999999999988876542 333332 1 3567789999999999888766643
4327
4328
4329 Q sp|P0DTC2|SPIK 102 R-----------------GWIFGTTLDSKT---Q------SLLIVNNATNVVI-------KVCEFQFCNDPFLGVYYHKN 148 (1273)
4330 Q Consensus 102 r-----------------gwifgttldskt---q------sllivnnatnvvi-------kvcefqfcndpflgvyyhkn 148 (1273)
4331 . .++||+|.+... + +++|+++-.+.++ ...+..-|..|..-+++.-+
4332 T Consensus 142 g~~~~~~~~~~~~~~~ypa~~fGsTF~Nts~~~~~~~~~~tlVI~P~~~g~~~~~~~c~~~prtit~C~~p~~~~~p~~~ 221 (1359)
4333 T 6Q04_B 142 GTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYCILEPRSGNHCPAGNSYTSFATY 221 (1359)
4334 T ss_dssp EEETTEEEEEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEEEEEECCSBTSTTSSSCCCCCEE
4335 T ss_pred CCeeeCCccccchhhhccceEeeccccCCCCCccccccceEEEEecCCCCchheeeeecccccccCcCCCCCeEeeeeec
4336 Confidence 2 256999998666 5 8899988887543 32333345555555554222
4337
4338
4339 Q sp|P0DTC2|SPIK 149 N---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNID-GYFKIYSKHTPINL--- 212 (1273)
4340 Q Consensus 149 n---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknid-gyfkiyskhtpinl--- 212 (1273)
4341 . .+|..+ +++.|....+|+|.|. +.|-+|... ..|- |.|+..| |.|-+|.-++..+.
4342 T Consensus 222 ~~~~~~~~~~~~~~n~~~~~~~~~~~~~~~~~~~~-~nfT~d~~~--~wf~----~~F~~~~~G~f~~Y~~d~~~~~~f~ 294 (1359)
4343 T 6Q04_B 222 HTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDEIL--EWFG----ITQTAQGVHLFSSRYVDLYGGNMFQ 294 (1359)
4344 T ss_dssp ECHHHHBCSSCBCTTHHHHHHHHHEEEEEEEEEEE-EECCCCCCC--EEEE----EEEETTEEEEEESTTTCTTTCCBEE
4345 T ss_pred CCCCccCCCCcccccccccchhHhcccCCceEEEe-eecCcchhh--heee----EEeeecCceeEEEEEEecCCCccee
4346 Confidence 1 245333 6778889999999875 344333211 1121 9999999 99999876654432
4347
4348
4349 Q sp|P0DTC2|SPIK 213 VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCA 292 (1273)
4350 Q Consensus 213 vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdca 292 (1273)
4351 ..-+| |+..+.+.. .+-|+..++ .+.+. ..++|||++|.+|+|||+|++||.|++||||+
4352 T Consensus 295 f~~~~-~~~~~~yy~---------------v~p~~~~~~---~~~~~-~~~~~yv~~L~~~~~Ll~fd~nG~I~~avDC~ 354 (1359)
4353 T 6Q04_B 295 FATLP-VYDTIKYYS---------------IIPHSIRSI---QSDRK-AWAAFYVYKLQPLTFLLDFSVDGYIRRAIDCG 354 (1359)
4354 T ss_dssp EEEEC-CCSCCCEEE---------------ECCEEECCC---GGGCC-EECCEEEEECEEEEEEEEECTTSCEEEEEETT
4355 T ss_pred ccccc-ceeccceee---------------eeeeeecCC---ccccc-eeEEEEEEEccceeEEEeecCCCeEEEEEecC
4356 Confidence 12222 444444443 233444444 34455 77899999999999999999999999999999
4357
4358
4359 Q sp|P0DTC2|SPIK 293 LDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSA 372 (1273)
4360 Q Consensus 293 ldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsa 372 (1273)
4361 -|+++|-||..+||.+++|+|++|+||+||....+|.++. ..|+|.++++ .++.++|.|.|+.++||..|+|+|++..
4362 T Consensus 355 ~~~~sEL~C~~~sf~~~tGVY~~S~y~aqp~~~v~~~~~~-~~C~~~~~~~-~~~P~p~~w~R~~f~nCnfN~s~Lls~~ 432 (1359)
4363 T 6Q04_B 355 FNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEG-VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLF 432 (1359)
4364 T ss_dssp SCHHHHHHHHTTSSCCCSEEEEEEEECCCCSCEEEECCCS-CBCCCGGGGS-BCCCBGGGCEEEEECSEEECHHHHHTTS
4365 T ss_pred CCccchheeEeceecCCCCeeecCCEEEEeeeEEEEecCC-CCCCchHHhc-CCCCCcceeEEeEEecCCCcHHHHHhhc
4366 Confidence 9999999999999999999999999999999999999999 9999999999 8899999999999999999999999999
4367
4368
4369 Q sp|P0DTC2|SPIK 373 SFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKV--GGNYN 450 (1273)
4370 Q Consensus 373 sfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskv--ggnyn 450 (1273)
4371 .+++|+||||+|.||.+.||..|++|.|.|..+..++++||++|-|++||||+|+||+||+++|+-...+..+ -.+|+
4372 T Consensus 433 ~~~sF~C~gIspskLa~mCfsSvtiD~Faip~~~k~~Lq~G~~G~i~~yNYKld~~~~gC~l~y~~pa~~vn~t~p~~y~ 512 (1359)
4373 T 6Q04_B 433 SVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYS 512 (1359)
4374 T ss_dssp EEEEEEEESSCHHHHTTCCBSEEEEEEEECCGGGGGGGSTTBCSHCCCCCCCCCSSSCEEEEEEECCTTCTTBCCCSEEE
4375 T ss_pred eeeeeeecCCCHHHHcccccceeeEEEEecCccccceecCCCCChhhhccccCCCCCCccEEEEEcCccccccCCCccce
4376 Confidence 9999999999999999999999999999999999999999999999999999999999999999955533322 44555
4377
4378
4379 Q sp|P0DTC2|SPIK 451 YLYRLFRKSNLKPFERDISTEI---YQAGSTPCNGV-EGFNCYFPLQSY-----------GFQP----TNGVGYQPYRVV 511 (1273)
4380 Q Consensus 451 ylyrlfrksnlkpferdistei---yqagstpcngv-egfncyfplqsy-----------gfqp----tngvgyqpyrvv 511 (1273)
4381 |+.|-+++.. ++. ++. ..+ .+-|+-. ...+|+.|...+ |..| ..++++|++.++
4382 T Consensus 513 yi~~~~~~~~-----~~~-~~~~~~~~~-~~~cpc~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~g~~ 585 (1359)
4383 T 6Q04_B 513 YINKCSRLLS-----DDR-TEVPQLVNA-NQYSPCVSIVPSTVWEDGDYYRKQLSPLEGGGWLVASGSTVAMTEQLQMGF 585 (1359)
4384 T ss_dssp EEEEEEEECT-----TSS-CEEECCCCT-TSCCGGGGTSCSSCSSTTCEEEEECCGGGTSSEEEEEEEEEECCSSCEEEE
4385 T ss_pred eeeeeeccCC-----CCC-Ccchhhccc-cccCCCCccCCccccCCCCccccccccccCCchhcccccccccccceeEEE
4386 Confidence 5555555333 222 222 111 1112100 112455543322 2333 458999999999
4387
4388
4389 Q sp|P0DTC2|SPIK 512 VLSFELLHAPATVCGP-----KKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILD 586 (1273)
4390 Q Consensus 512 vlsfellhapatvcgp-----kkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleild 586 (1273)
4391 |++++..+.++|||++ |.+|.++.++||++++.|+||+||++|+++.+.++|+|..|-.+-..++|| +++++.+
4392 T Consensus 586 Vis~k~~~~s~tVCp~~~d~~~~~T~~~lg~CVnY~LYGiTGtGVf~~s~~~~~s~Q~f~yDs~Gnl~gf~d-~tn~~Y~ 664 (1359)
4393 T 6Q04_B 586 GITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQRFVYDAYQNLVGYYS-DDGNYYC 664 (1359)
4394 T ss_dssp EEEEESSSSCCCEEECCCCCTTSCSGGGTTSEEEEEETTEEEEEEEEECCCCSCGGGCEEECTTSCEEEEEC-TTSCEEE
4395 T ss_pred EEEeEcCCCcCccCCCccccCCCCcchhcCceeEEEecceeeeeEEEecCceeecceeeEEeCCCCEEEEEe-CCCCEEE
4396 Confidence 9999999999999998 667999999999999999999999999999999999999999999999999 8999999
4397
4398
4399 Q sp|P0DTC2|SPIK 587 ITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRV--YSTGSNVFQTRAGCLIGAEHVNN-SYECD 663 (1273)
4400 Q Consensus 587 itpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrv--ystgsnvfqtragcligaehvnn-syecd 663 (1273)
4401 |.||..|+|||+++++ ++.+|+||++++|.+|+...+..+.+|.||+ +++..+.|||-+||++||++.+. .+|||
4402 T Consensus 665 I~PC~sg~VSV~y~~~--s~e~AlLf~~l~C~~v~~~~~~~~~~~~~~l~~~~~~~~~fdT~~GCVvnA~n~t~~V~~C~ 742 (1359)
4403 T 6Q04_B 665 LRACVSVPVSVIYDKE--TKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGPLQTPVGCVLGLVNSSLFVEDCK 742 (1359)
4404 T ss_dssp EECCCCEEEEEEEETT--TTEEEEEEETCCGGGC---------------------CCCEEETTEEEESEEEEEEEESSCS
4405 T ss_pred EeeceEEeeeEEEcCC--CCCeEEEEccccccHhhcceeeccCCCccccccccCCCCCCCCccceeeeceecCCceeeCC
4406 Confidence 9999999999999998 8999999999999999999999999999998 77788999999999999999988 89999
4407
4408
4409 Q sp|P0DTC2|SPIK 664 IPIGAGICASYQTQTNSPR-RARSVAS-QSII--AYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCT 739 (1273)
4410 Q Consensus 664 ipigagicasyqtqtnspr-rarsvas-qsii--aytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdct 739 (1273)
4411 +|+|.|+|+.|.+...+.| +.|++.. ..+. +|+|.+-. .++.+++..|.||+||||+|++|-++++|.|.+|||.
4412 T Consensus 743 LplG~glC~~y~~~s~~~~r~~~~~~~~~~l~~~~y~~P~~~-~~~~~~~~~i~IP~nFt~~v~~EyiQ~~~~kv~iDC~ 821 (1359)
4413 T 6Q04_B 743 LPLGQSLCALPDTPSTLTPASVGSVPGEMRLASIAFNHPIQV-DQLNSSYFKLSIPTNFSFGVTQEYIQTTIQKVTVDCK 821 (1359)
4414 T ss_dssp SEEETTEEEECCCC------------CCEEEEEECCCCCEEC-CCCSSSCEEEEECSEEEEEEEEEEEECCCCEEEECHH
4415 T ss_pred CCCCceeecCCCCCCCCCCcccCCCCCceEEEEEeecCCeee-cccCCCCeeEEcccceEEEEEEEEEeecCCceEEech
4416 Confidence 9999999999998774433 3343333 3344 77787766 7888999999999999999999999999999999999
4417
4418
4419 Q sp|P0DTC2|SPIK 740 MYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF-GGFNFSQILPDPS---KPSKR 815 (1273)
4420 Q Consensus 740 myicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf-ggfnfsqilpdps---kpskr 815 (1273)
4421 +|+||++.+|.+||.|||+||..+|+||.|.+.++|.+..+++..+++-++.+-+..| |+|||+.+||... ++++|
4422 T Consensus 822 ~YVC~~~~~C~~lL~qYgs~C~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~~~~~~f~~~~N~s~ll~~~~~~~~~~~R 901 (1359)
4423 T 6Q04_B 822 QYVCNGFQKCEQLLREYGQFCSKINQALHGANLRQDDSVRNLFASVKSSQSSPIIPGFGGDFNLTLLEPVSISTGSRSAR 901 (1359)
4424 T ss_dssp HHHHTTCHHHHHHHGGGCSHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSEECCCCTTTTTTSCCTTTSBC--------CC
4425 T ss_pred hhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHhhccHHHHHHHHhccccccCCCcCCCCCCcccceeccCCCCCCCccce
4426 Confidence 9999999999999999999999999999999999999999999999999998888887 5799999999875 34689
4427
4428
4429 Q sp|P0DTC2|SPIK 816 SFIEDLLFNKVTLADAGFIKQYGDCLGDI--AARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAA 893 (1273)
4430 Q Consensus 816 sfiedllfnkvtladagfikqygdclgdi--aardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaa 893 (1273)
4431 |+||||||+||.+.+.||...|+.|.... ..+||+|||.+||+.||||..++||.++|+.+++.+....||++|..++
4432 T Consensus 902 S~ieDLLF~Kv~~~~~G~~~~y~~c~~g~~~~i~Dl~caq~~NGi~VLP~v~~~~le~~Yt~SdvG~l~~~r~e~G~tsa 981 (1359)
4433 T 6Q04_B 902 SAIEDLLFDKVTIADPGYMQGYDDCMQQGPASARDLICAQYVAGYKVLPPLMDVNMEAAYTSSLLGSIAGVGWTAGLSSF 981 (1359)
4434 T ss_dssp BHHHHHHHHTSCCCCCCTTTHHHHHHHTCCSSTTCTTTTHHHHTEEEECCSSCHHHHHHHHHHHHTTHHHHSSSSSSSCE
4435 T ss_pred eHHHHHhcceeeeCCCCcccChhhhcccCCccHHHHhheeEeCCEeecCCccCHHHHHHHHHHHHHhhhcccccccCCcc
4436 Confidence 99999999999999999999999999555 8999999999999999999999999999999999988888999999999
4437
4438
4439 Q sp|P0DTC2|SPIK 894 LQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAI 973 (1273)
4440 Q Consensus 894 lqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgai 973 (1273)
4441 ..|||++++.+|+|+++++|++|.+|||.|||.||.|||.||+.+.++++||.|+|++||+++++|++|..||+.|||||
4442 T Consensus 982 aaIpfs~~Vy~RLN~l~~~~~vL~~nq~~Ia~sFN~AI~~iq~Gf~t~~~Al~kIq~vVN~~~~aLs~L~~qLn~nFgAI 1061 (1359)
4443 T 6Q04_B 982 AAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLASELSNTFGAI 1061 (1359)
4444 T ss_dssp EECCHHHHHHHHHHTTTCCHHHHHHTHHHHHHHHHHHHHTTTTCCSTTCHHHHHHHHHHHHHHHHHHHHHHHTTCCTTSS
4445 T ss_pred ccCCchHHHHHHHHhhhchHHHHHHHHHHHHHHHHHHHHHHhhccccHHHHHHHHHHHHHHHHHHHHHHHHHHhhhcccc
4446 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4447
4448
4449 Q sp|P0DTC2|SPIK 974 SSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFP 1053 (1273)
4450 Q Consensus 974 ssvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfp 1053 (1273)
4451 ||.+++|+.|||++||++|+||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+|
4452 T Consensus 1062 Sssi~gI~~RLd~lEA~iqvdrlInGRL~aLnafVtq~l~~~~~v~~sr~LA~qKiNECVKSQS~R~gFCGnGtHi~S~~ 1141 (1359)
4453 T 6Q04_B 1062 SASIGDIIQRLDPPEQDAQIDRLINGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFV 1141 (1359)
4454 T ss_dssp CSCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTSSSSEEEEEEE
4455 T ss_pred hhcHhHHHHhcchHHHHhCCChhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEEe
4456 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4457
4458
4459 Q sp|P0DTC2|SPIK 1054 QSAPHGVVFLHVTYVPAQEKNFTTAPAICHD---GKAHFPREGVFVSNG-----THWFVTQRNFYEPQIITTDNTFVSGN 1125 (1273)
4460 Q Consensus 1054 qsaphgvvflhvtyvpaqeknfttapaichd---gkahfpregvfvsng-----thwfvtqrnfyepqiittdntfvsgn 1125 (1273)
4461 |.||+|++|+|++|+|.+.++.+++|.+|++ +++..|+.|.|+.+. .+|++|.|++|||..||.+|+. --.
4462 T Consensus 1142 q~AP~Gi~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~p~~g~~v~~~~~~~~~~~~~T~r~~y~P~~~t~~dv~-i~s 1220 (1359)
4463 T 6Q04_B 1142 VNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDEWSYTGSSFYAPEPITSLNTK-YVA 1220 (1359)
4464 T ss_dssp EEETTEEEEEEEEEEEESCEEEEEESCEEESSSTTCEEEESSEEEEEC-------CEEEEETTEEEEECCCTTSEE-EEC
4465 T ss_pred eccCCeEEEEEEEeccCceeEEEEEeEEecCCCCCceeeccCeEEEEeCCceeeceEEEeCCccccCccCCccCEE-EEC
4466 Confidence 9999999999999999999999999999996 689999999999876 5799999999999999999955 577
4467
4468
4469 Q sp|P0DTC2|SPIK 1126 CDVVIGIVNNTVYDPL--QPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
4470 Q Consensus 1126 cdvvigivnntvydpl--qpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
4471 |||....+|+++..|+ +|+...|+|||+|+|||+++...|+.+++.+|++++|++.||++|+|+.|+||+++|||++|
4472 T Consensus 1221 c~V~y~n~~~~~l~~~v~~pdyiDf~~el~~~~~n~~~~~p~l~~l~~~N~T~LNLt~EI~~Lq~~i~~LN~s~idLe~L 1300 (1359)
4473 T 6Q04_B 1221 PQVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSIPNFGSLTQINTTLLDLTYEMLSLQQVVKALNESYIDLKEL 1300 (1359)
4474 T ss_dssp CCTTSEEECSSCCTTTCC--------------------------------------------------------------
4475 T ss_pred CcceeEecCCCCCCCccCCCCCCChHHHHHHHHhcCCCCCCCCCccccceeeecchHHHHHHHHHHHHHHHhcCCCHHHh
4476 Confidence 8999999999999984 67999999999999999999888888899999999999999999999999999999999999
4477
4478
4479 Q sp|P0DTC2|SPIK 1204 GKYEQYIKWPWYIWLGFIAGL 1224 (1273)
4480 Q Consensus 1204 gkyeqyikwpwyiwlgfiagl 1224 (1273)
4481 ++||+||||||||||||-.|-
4482 T Consensus 1301 n~~e~YiKWPWYvWL~~~~~~ 1321 (1359)
4483 T 6Q04_B 1301 GNYTYYNKGSGRENLYFQGGG 1321 (1359)
4484 T ss_dssp ---------------------
4485 T ss_pred CceeEEeccCchhheeecCCC
4486 Confidence 999999999999999998763
4487
4488
4489 No 4
4490 >5I08_C Spike glycoprotein; coronavirus, glycoprotein, prefusion, VIRAL PROTEIN; 4.04A {Human coronavirus HKU1 (isolate N5)}
4491 Probab=100.00 E-value=1.5e-199 Score=1685.13 Aligned_cols=1142 Identities=29% Similarity=0.491 Sum_probs=772.9 Template_Neff=4.000
4492
4493 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNI------ 100 (1273)
4494 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksni------ 100 (1273)
4495 -+-.+|+||||..++++..+-.|+||.+.-++.+-.- .+|++- --.++++..||+||+++...+.+|-
4496 T Consensus 29 vs~~~G~yYPd~rvysN~TlL~qglfp~~gs~~~~y~---~~~t~~~~~~~~y~~~~~~F~dGifvkv~~~~n~t~~~~~ 105 (1299)
4497 T 5I08_C 29 VSLGLGTYYVLNRVYLNTTLLFTGYFPKSGANFRDLA---LKGSIYLSTLWYKPPFLSDFNNGIFSKVKNTKLYVNNTLY 105 (1299)
4498 T ss_dssp TTSSSSCBCCTTEECCSEEEEEEEEECCTTCEEEECC---CBCSSCEEGGGGSTTTEEECSSEEEEEEECCCEESSSCEE
4499 T ss_pred cccceeEEEecceEEeceeeeeeCeecCCCCceeeee---eecccccccceecCCCcccccCcEEEEeeecccCCCCccc
4500 Confidence 3556899999999999999999999999988876542 233332 3467888999999999998887764
4501
4502
4503 Q sp|P0DTC2|SPIK 101 --IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMD 178 (1273)
4504 Q Consensus 101 --irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmd 178 (1273)
4505 -..++||+|.+...++++|+++-+...|.+|.|..|..|.+.+++ |..+.. +++. ....+|+|.|. +.|-+|
4506 T Consensus 106 ~~~pa~~fGsTF~N~s~tvVI~P~~~~~~it~C~~~vC~~p~~~~~p--~~~~~~--~~~~-~d~~~~~~~~~-~nfT~d 179 (1299)
4507 T 5I08_C 106 SEFSTIVIGSVFVNTSYTIVVQPHNGILEITACQYTMCEYPHTVCKS--KGSIRN--ESWH-IDSSEPLCLFK-KNFTYN 179 (1299)
4508 T ss_dssp CCCCCEEEESSCSTTSCEEEEEEETTEEEEEEECCCCCSSCCBCCSS--SCCSCC--CTTS-TTCSCCCEEEE-EEEECC
4509 T ss_pred eecceeEEeccccCCcEEEEEeCCCceEEEEEEEEEecCCCceEEec--CCCccc--eeee-EeCCCCeEEEe-eccccc
4510 Confidence 356789999999999999999999999999999999999987776 332222 3334 56778888653 444343
4511
4512
4513 Q sp|P0DTC2|SPIK 179 LEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGW 258 (1273)
4514 Q Consensus 179 legkqgnfknlrefvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgw 258 (1273)
4515 ... ..| .|.|++.||.|-+|..+...+ ..| +...++|...+.+- .+-|+..++ ++.+
4516 T Consensus 180 ~~~--~~~----~f~F~~~dG~f~~Yyad~~~~------~~f-----~f~~~~~~~~~~yy---vip~~~~~~---~~~~ 236 (1299)
4517 T 5I08_C 180 VSA--DWL----YFHFYQERGVFYAYYADVGMP------TTF-----LFSLYLGTILSHYY---VMPLTCNAI---SSNT 236 (1299)
4518 T ss_dssp TTC--SEE----EEEEEEETTEEEEEEESSCSS------BEE-----EEEEECCSCCCEEE---ECCBCSTTS---SSSG
4519 T ss_pred ccc--eee----EEEEEEeCCEEEEEEeccCCC------cce-----eecccceeecceee---eceeeccCC---CCCC
4520 Confidence 322 111 299999999998875543222 111 11111232222222 333444444 5667
4521
4522
4523 Q sp|P0DTC2|SPIK 259 TAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPF 338 (1273)
4524 Q Consensus 259 tagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpf 338 (1273)
4525 ....++|||++|.+|+|||+|+.||.|++||||+-|+++|-||..+||.+++|+|++|+||+||...++|.+.....|+|
4526 T Consensus 237 ~~~~~~~~v~~L~~~~~Ll~fd~~G~It~AvDC~~~~~sEL~C~t~Sf~~~tGVY~lS~y~aqP~~~V~~~~~~~~~C~~ 316 (1299)
4527 T 5I08_C 237 DNETLEYWVTPLSRRQYLLNFDEHGVITNAVDCSSSFLSEIQCKTQSFAPNTGVYDLSGFTVKPVATVYRRIPNLPDCDI 316 (1299)
4528 T ss_dssp GGCCCCEEEEECEEEEEEEEECTTCCEEEEECGGGCHHHHHHHHHTSSSCCSCEEEEC--------CEEECCSSCCCCCH
4529 T ss_pred CccceeEEEeecccceEEEEeCCCCeEeEEEecccCcchhheeeecccCCCCCeeecCCeEEEeeeEEEEecCCCCCCCH
4530 Confidence 78889999999999999999999999999999999999999999999999999999999999999999999999899999
4531
4532
4533 Q sp|P0DTC2|SPIK 339 GEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKI 418 (1273)
4534 Q Consensus 339 gevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgki 418 (1273)
4535 .+++++.++.++|.|.|+.++||..|+++|++..++++|+|||+||.||.+.||..|++|.|.|..+..++++||++|-|
4536 T Consensus 317 ~~~~~~~~~P~p~~w~R~~f~nCnfn~s~Lls~~~~~~f~C~~ispskl~~mCfsSvtiD~Faip~s~~~~L~~g~~g~i 396 (1299)
4537 T 5I08_C 317 DNWLNNVSVPSPLNWERRIFSNCNFNLSTLLRLVHVDSFSCNNLDKSKIFGSCFNSITVDKFAIPNRRRDDLQLGSSGFL 396 (1299)
4538 T ss_dssp HHHHTCSEEECGGGCEEEEECSCEECHHHHHHTSEEEEEEEESSCHHHHHHCCCSCEEEEEEECCSTTGGGGSSSCCSSC
4539 T ss_pred HHHhhCCCCCCccceEEeEEecCCCCHHHHHhhceeeeeeeeCCCHHHhcccccCeeEEEEEeccCcchHhcCCCCCcHh
4540 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4541
4542
4543 Q sp|P0DTC2|SPIK 419 ADYNYKLPDDFTGCVIAWNSNNLDSKV----GGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCN------------- 481 (1273)
4544 Q Consensus 419 adynyklpddftgcviawnsnnldskv----ggnynylyrlfrksnlkpferdisteiyqagstpcn------------- 481 (1273)
4545 ++||||+|++|+||+++|+-.+.+..+ -++||.-|+. +..++++.++..+..-..++++-|.
4546 T Consensus 397 ~~~NYkl~~~~~sC~l~~~~~~~~vt~t~~nps~~n~ry~~-~~~~~~~hdv~Ys~~cf~~~~~~cPC~~p~~~~~~~~~ 475 (1299)
4547 T 5I08_C 397 QSSNYKIDISSSSCQLYYSLPLVNVTINNFNPSSWNRRYGF-GSFNLSSYDVVYSDHCFSVNSDFCPCADPSVVNSCAKS 475 (1299)
4548 T ss_dssp CCCCCCCCCSSSEEEEEEEEESSSCEEECCCCSCCTTTCCC-CCCSSEEECCCSCCCCCTTCCCCCCC------------
4549 T ss_pred HhccccCCCCCCceEEEEEcccccceecCCCcccchhccCc-cccCCCccceeeeccccccCCCCCCCCChhhcccCcCC
4550 Confidence 999999999999999999966655444 3567766665 6667888888888777766655443
4551
4552
4553 Q sp|P0DTC2|SPIK 482 --------------------------------GVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFEL------------ 517 (1273)
4554 Q Consensus 482 --------------------------------gvegfncyfplqsygfqptngvgyqpyrvvvlsfel------------ 517 (1273)
4555 +..+..|+-+...+.....-|+|++.+++.|++.+.
4556 T Consensus 476 ~~~~~~~~~~t~~r~c~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~q~~~~vg~g~~c~g~~V~~~k~g~~~~~~~c~c~ 555 (1299)
4557 T 5I08_C 476 KPPSAICPAGTKYRHCDLDTTLYVKNWCRCSCLPDPISTYSPNTCPQKKVVVGIGEHCPGLGINEEKCGTQLNHSSCFCS 555 (1299)
4558 T ss_dssp --------------------------------------------------------------------------------
4559 T ss_pred CCCCCCCCCCCcceecccccccccccccccccCCCCCCccCCCCCCCceeeeecccccCeeEEEeeecCCCCCCCCcccC
4560 Confidence 111344554554444455679999999999999888
4561
4562
4563 Q sp|P0DTC2|SPIK 518 ---------------------------LHAPATVCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTE-SNKKFLPFQQFG 566 (1273)
4564 Q Consensus 518 ---------------------------lhapatvcgp---kkstnlvknkcvnfnfngltgtgvlte-snkkflpfqqfg 566 (1273)
4565 ...++|+|+. +.+++++.++||++|..|.||+||+++ ++..++.+|.+.
4566 T Consensus 556 ~~af~gws~dsc~~~~~~~~~~~~~~~~~~t~Tvcp~~~~~~~snI~Ln~CVdYNIYG~TGtGVItnvt~s~~~~~qGL~ 635 (1299)
4567 T 5I08_C 556 PDAFLGWSFDSCISNNRCNIFSNFIFNGINSGTTCSNDLLYSNTEISTGVCVNYDLYGITGQGIFKEVSAAYYNNWQNLL 635 (1299)
4568 T ss_dssp ---CCSCCEEECCBTTEEEEEEEEEESSSSSSSCEECTTCCCCCCCCCSSSEEEEETTEEEEEEEEECCCCCCCTTTCEE
4569 T ss_pred ccccccccccccccCCccccccceeccCCCCCCcCCCccccCCceeEeCeeEeEEeCCCeeEEEEEeCCCceeecCCcEE
4570 Confidence 5668999998 467899999999999999999999999 444467788888
4571
4572
4573 Q sp|P0DTC2|SPIK 567 RDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTR 646 (1273)
4574 Q Consensus 567 rdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtr 646 (1273)
4575 .|-+.-..++|++.++++..|+||..+.++++..|. +...+.+++.++|.++..... +....+-|+|.
4576 T Consensus 636 ydssGdLlgFKn~ttg~iYsV~PC~~v~vqvVv~~~--~~vgall~~n~~cs~~~~n~~----------~~~~~~~~~t~ 703 (1299)
4577 T 5I08_C 636 YDSNGNIIGFKDFLTNKTYTILPCYSGRVSAAFYQN--SSSPALLYRNLKCSYVLNNIS----------FISQPFYFDSY 703 (1299)
4578 T ss_dssp EETTEEEEEEECTTTCCEEEEECCCCCCEEEECCCC-----CEEEEETCCHHHHHHTC----------------CCEECS
4579 T ss_pred EeCCCCEEEEEeCCCCcEEEEEeCcccceEEEEeCC--CcceeEEeecCcccceeecee----------eecCccceecc
4580 Confidence 888888889999999999999999999999998876 344689999999988765311 22222559999
4581
4582
4583 Q sp|P0DTC2|SPIK 647 AGCLIGAEHVNN--SYECDIPIGAGICASYQTQTNSPRRARSVAS--QSIIAYTMSL-----GAENSVAYSNNSIAIPTN 717 (1273)
4584 Q Consensus 647 agcligaehvnn--syecdipigagicasyqtqtnsprrarsvas--qsiiaytmsl-----gaensvaysnnsiaiptn 717 (1273)
4585 .||.+++++... ..+|+.|.|.|+|+.+.+. +++++++..+ .++..| +.. -....+..+...|.||+|
4586 T Consensus 704 ~gc~~~~~~~t~~~v~~c~~~~~~~~C~~~~~~--~~~g~~~~~~~~~~l~~~-~p~~~~~~~~~~~~~~~~~~IsIPtN 780 (1299)
4587 T 5I08_C 704 LGCVLNAVNLTSYSVSSCDLRMGSGFCIDYALP--SSGGSGSGISSPYRFVTF-EPFNVSFVNDSVETVGGLFEIQIPTN 780 (1299)
4588 T ss_dssp SEEESSCBCCCSSBCSSCSCBCSTTEEEEC----------------CCEEEEC-CCCC---------------------C
4589 T ss_pred cceeeeceeccCCccccCccccCCceeeecCCC--CCCCCCCCcCCCeeeeEe-cceeeeecCCcccccceEEEEEccCC
4590 Confidence 999999976644 7789999999999999877 5555554332 234443 221 011124445558999999
4591
4592
4593 Q sp|P0DTC2|SPIK 718 FTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTP-P--- 793 (1273)
4594 Q Consensus 718 ftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktp-p--- 793 (1273)
4595 |||+|++|-++++|.|.+|||.+|+||++.+|.+||.|||+||..+++||.|.+..+|....+++..+++-++++ +
4596 T Consensus 781 FTisv~~EyiQt~~~kVsVDCa~YVCngn~~C~~lL~qYgs~C~~i~~~l~~~~~~~~~~~~~~~~~~~~~~~~ss~~~~ 860 (1299)
4597 T 5I08_C 781 FTIAGHEEFIQTSSPKVTIDCSAFVCSNYAACHDLLSEYGTFCDNINSILNEVNDLLDITQLQVANALMQGVTLSSNLNT 860 (1299)
4598 T ss_dssp CCCCEEEECCCCCCCEEEECTTTTTCCSCTHHHHHHHHHCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCTTCCC
4599 T ss_pred ceeEEEEEEeeccCCCeEEecceeecCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhhcHHHHHHHHHHhccccccccccc
4600 Confidence 999999999999999999999999999999999999999999999999999999999999999999999988775 3
4601
4602
4603 Q sp|P0DTC2|SPIK 794 --IKDFGGFNFSQILPDPSK---PSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDE 868 (1273)
4604 Q Consensus 794 --ikdfggfnfsqilpdpsk---pskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltde 868 (1273)
4605 +..+++|||+.+||.+.. +++||+||||||+||..+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++|
4606 T Consensus 861 ~~~~~~~~~N~s~ll~~~~~~~~~~~RS~IEDLLF~KV~t~glG~~~~Y~~Ct~g~~i~DL~CaQ~yNGi~VLP~v~d~~ 940 (1299)
4607 T 5I08_C 861 NLHSDVDNIDFKSLLGCLGSQCGSSSRSLLEDLLFNKVKLSDVGFVEAYNNCTGGSEIRDLLCVQSFNGIKVLPPILSET 940 (1299)
4608 T ss_dssp ----------------------------CHHHHGGGTSCCCHHHHHHHHHTTSSSCSCCTTHHHHHHSSEEEECCSSCHH
4609 T ss_pred CcccCCCCccchhhcccccCCCCCCcccHHHHHhcCceEeCCCChhHHHHHccCCccHHHHhcccccCeEEEeCCCCCHH
4610 Confidence 378899999999998763 479999999999999999999999999999999999999999999999999999999
4611
4612
4613 Q sp|P0DTC2|SPIK 869 MIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKL 948 (1273)
4614 Q Consensus 869 miaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgkl 948 (1273)
4615 |+|.||++|++|....|||+ |..||||+||.||+||+|+||+||.||||+|||.||.||+.||+.+.++++||.|+
4616 T Consensus 941 ~~amYTasL~g~m~~gg~T~----aaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~iq~~f~~~~~Al~ki 1016 (1299)
4617 T 5I08_C 941 QISGYTTAATVAAMFPPWSA----AAGVPFSLNVQYRINGLGVTMDVLNKNQKLIANAFNKALLSIQNGFTATNSALAKI 1016 (1299)
4618 T ss_dssp HHHHHHHHHHHHHHCTTTCS----SSSSCHHHHHHHHHTTSSCSSSHHHHTTTHHHHHHHHHHHHHHGGGGSCCSHHHHH
4619 T ss_pred HHHHHHHHHHHHhhccCchh----cccCchHHHHHHHhchhcccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4620 Confidence 99999999999999999997 55689999999999999999999999999999999999999999999999999999
4621
4622
4623 Q sp|P0DTC2|SPIK 949 QDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATK 1028 (1273)
4624 Q Consensus 949 qdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatk 1028 (1273)
4625 |||||++++||++|++||+.|||||||.++||++|||++||++||||||+|||.+|++||+|||+|++|+|||+.||..|
4626 T Consensus 1017 Q~VVN~~~~aL~~L~~qL~~nFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qK 1096 (1299)
4627 T 5I08_C 1017 QSVVNANAQALNSLLQQLFNKFGAISSSLQEILSRLDNLEAQVQIDRLINGRLTALNAYVSQQLSDITLIKAGASRAIEK 1096 (1299)
4628 T ss_dssp HHHHHHHHHHHHHHHHGGGCCSSSSSCSTHHHHHHCCSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4629 T ss_pred HHHHHHHHHHHHHHHHHHHHHHcHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4630 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4631
4632
4633 Q sp|P0DTC2|SPIK 1029 MSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQR 1107 (1273)
4634 Q Consensus 1029 msecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqr 1107 (1273)
4635 |.|||..||+|.+|||.|.|++|+||.||+|++|+|++|+|.+.++.+++|.+|+++ ++..|++|+|+.+...|++|.|
4636 T Consensus 1097 INECVkSQS~R~gFCGnGtHi~Si~q~APnGi~FlH~~y~Pt~~~~V~a~~GlC~~~~~~~~~~~g~f~~~n~~~~~T~r 1176 (1299)
4637 T 5I08_C 1097 VNECVKSQSPRINFCGNGNHILSLVQNAPYGLLFIHFSYKPTSFKTVLVSPGLCLSGDRGIAPKQGYFIKQNDSWMFTGS 1176 (1299)
4638 T ss_dssp CCCCCTSCCSCSSSSCSSCCSEEEEEEETTEEEEEEEC------------------------------------------
4639 T ss_pred HHHHHhcCCCCccccCCCeEEEeeeeccCCeEEEEEEEecCCeeeEEEEEeeEEecCCeeEEecCcEEEeeCCEEEEecc
4640 Confidence 999999999999999999999999999999999999999999999999999999995 7999999999999999999999
4641
4642
4643 Q sp|P0DTC2|SPIK 1108 NFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLN 1187 (1273)
4644 Q Consensus 1108 nfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrln 1187 (1273)
4645 ++|||..||.+|...-..|||....+|+++..+..|++..|+|||+|+|||+++...|+.++..+|++++|++.||++|+
4646 T Consensus 1177 ~~y~Pr~~t~~d~v~~~sC~v~y~n~~~~~~~~~~p~~~df~~el~~~~~n~~~~~p~~~~~~~~n~t~LNLt~EI~~Lq 1256 (1299)
4647 T 5I08_C 1177 SYYYPEPISDKNVVFMNSCSVNFTKAPFIYLNNSIPNLSDFEAELSLWFKNHTSIAPNLTFNSHINATFLDLYYEMNVIQ 1256 (1299)
4648 T ss_dssp --------------------------------------------------------------------------------
4649 T ss_pred ccccCCCCCccCeEEeccceeEEEEcChhhCCCCCCCCCChHHHHHHHHhcCCCCCCCCCcccccccceechHHHHHHHH
4650 Confidence 99999999999999999999999999999999999999999999999999999977888878899999999999999999
4651
4652
4653 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELGKYEQYIKW-PWYIWLGFIAG 1223 (1273)
4654 Q Consensus 1188 evaknlneslidlqelgkyeqyikw-pwyiwlgfiag 1223 (1273)
4655 |+.|+||+++.+++.+.+.|.|+|| |||+||..+..
4656 T Consensus 1257 evIknLN~S~~ilE~l~~~e~YVkwdpwwVwL~i~l~ 1293 (1299)
4657 T 5I08_C 1257 ESIKSLNGSGYIPEAPRDGQAYVRKDGEWVLLSTFLG 1293 (1299)
4658 T ss_dssp -------------------------------------
4659 T ss_pred HHHHHHHhcCCCCCCCCCccceecccChhHHHHhhhh
4660 Confidence 9999999999999999999999998 99999976543
4661
4662
4663 No 5
4664 >5X5F_B S protein; MERS-CoV, spike glycoprotein, prefusion, single; 4.2A {Middle East respiratory syndrome coronavirus}
4665 Probab=100.00 E-value=6.1e-198 Score=1670.09 Aligned_cols=1163 Identities=31% Similarity=0.500 Sum_probs=888.5 Template_Neff=3.800
4666
4667 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
4668 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
4669 .|... -...-+.+.++ -+-.+|+||||..++++..+-.|+||.+.-++.+-.- ++|++. + -.+
4670 T Consensus 12 ~C~~~~~~~~~~~~~~~~~idvs~~~G~yYP~~rvysN~TlL~qglfP~~gs~~~~y~---~~~t~~~~~~~~~~~~~~y 88 (1323)
4671 T 5X5F_B 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (1323)
4672 T ss_dssp BCCCEEECGGGTCCCCCCCCCGGGTTTCBCCSSCCBSSCEEEEEEEECCTTCCCEEEC---CEECCBCSSCBCSEEECSG
4673 T ss_pred cceecccccccCCCCCCcceecccCceeEeeCCeeeeeeeeeeeceecCCCCcceEEE---EEecCCCCCCCcceeeecc
4674 Confidence 36554 23333445555 3446899999999999999999999999988876532 333333 1 356
4675
4676
4677 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIR-----------------GWIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
4678 Q Consensus 80 dnpvlpfndgvyfasteksniir-----------------gwifgttldskt---q------sllivnnatnvvi----- 128 (1273)
4679 +.+..||+||+++...+..|--. .++||+|.+... + +++|+++-.+.++
4680 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~tg~~~~~~~~~~~~~~~ypa~~fGstF~Nts~~~~~~~~~~tlVI~P~~~g~~~~~~~~ 168 (1323)
4681 T 5X5F_B 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (1323)
4682 T ss_dssp GGCCEECTTCEEEEESTTTTSEEECSSSTTCEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEE
4683 T ss_pred CCChhhccCeEEEEEeeeeccCCCeeeCCccccchhhhccceEeeccccCCCCCccccccceEEEEecCCCCchheeeee
4684 Confidence 77899999999998877666422 256999998666 5 8889888876543
4685
4686
4687 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
4688 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
4689 ...+..-|..|..-+++.-+. .+|..+ +++.|....+|+|.|. +.|-+|... ..|- |.|
4690 T Consensus 169 ~~~prtit~C~~p~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~-~nfT~d~~~--~wf~----~~F 241 (1323)
4691 T 5X5F_B 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDEIL--EWFG----ITQ 241 (1323)
4692 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHSCTTCCCTTHHHHHHHHHEEEEEEEEEEE-EECCCCCCC--EEEE----EEE
4693 T ss_pred cccccccCcCCCCCeEeeeeecCCCCccCCCCcccccccccchhHhcccCCceEEEe-eecCcchhh--heee----EEe
4694 Confidence 322333455555555432221 345333 6778889999999875 344333211 1111 899
4695
4696
4697 Q sp|P0DTC2|SPIK 195 KNID-GYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
4698 Q Consensus 195 knid-gyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
4699 +..| |.|-+|.-++..+. ..-+| |+..+.+.. .+-|+..++ .+.+. ..++|||++|
4700 T Consensus 242 ~~~~~G~f~~Y~~d~~~~~~f~f~~~~-~~~~~~yy~---------------v~p~~~~~~---~~~~~-~~~~~~v~~L 301 (1323)
4701 T 5X5F_B 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYS---------------IIPHSIRSI---QSDRK-AWAAFYVYKL 301 (1323)
4702 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEE---------------ECCEEECCC---GGGCC-EECCEEEEEC
4703 T ss_pred eecCceeEEEEEEeccCCcceeccccc-ceeccceee---------------eeeeeecCC---ccccc-eeEEEEEEEc
4704 Confidence 9999 99999876654332 12222 444444443 233444444 45566 7889999999
4705
4706
4707 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASV 350 (1273)
4708 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasv 350 (1273)
4709 .+|+|||+|++||.|++||||+-|+++|-||..+||.+++|+|++|+||+||....+|.++. ..|+|.++++ .++.++
4710 T Consensus 302 ~~~~yLl~fd~nG~I~~avDC~~~~~seL~C~~~sf~~~tGVY~~S~y~aqp~~~v~~~~~~-~~C~~~~~~~-~~~P~p 379 (1323)
4711 T 5X5F_B 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEG-VECDFSPLLS-GTPPQV 379 (1323)
4712 T ss_dssp EEEEEEEEECTTSCEEEEEETTSCHHHHHHHTTTCSCCCSSEECCCCCBBCCCSCEECC----CCCCCHHHHS-BCCCBG
4713 T ss_pred cceeEEEeecCCCeEEEEEecCCCccchheeEeceecCCCCeeecCCEEEEeeeEEEEecCC-CCCCchHHhc-CCCCCc
4714 Confidence 99999999999999999999999999999999999999999999999999999999999999 9999999999 889999
4715
4716
4717 Q sp|P0DTC2|SPIK 351 YAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFT 430 (1273)
4718 Q Consensus 351 yawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddft 430 (1273)
4719 |.|.|+.++||..|+|+|++...+++|+||||+|.||.++||..|++|.|.|..+..++++||++|-|++||||+|+||+
4720 T Consensus 380 ~~w~R~~f~nCnfN~s~Lls~~~~~sf~C~gIspskLa~mCfsSvtiD~Faip~s~~~~Lq~G~~G~i~~yNYKld~~~~ 459 (1323)
4721 T 5X5F_B 380 YNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNP 459 (1323)
4722 T ss_dssp GGCEEEEECSEEECHHHHHHHSEEEEEEEESSCHHHHHHSCCSCEEEEEEECCGGGGGGSCTTCCSHCCCCCCCCCSSSC
4723 T ss_pred ceeEEeEEecCCCcHHHHHhhceeeeeeecCCCHHHHcccccceeeEEEEecCccccceecCCCCChhhhccccCCCCCC
4724 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4725
4726
4727 Q sp|P0DTC2|SPIK 431 GCVIAWNSNNLDSKV--GGNYNYLYRLFRKSNLKPFERDISTEI---YQAGSTPCNGV-EGFNCYFPLQSY--------- 495 (1273)
4728 Q Consensus 431 gcviawnsnnldskv--ggnynylyrlfrksnlkpferdistei---yqagstpcngv-egfncyfplqsy--------- 495 (1273)
4729 ||+++|+-...+..+ -.+|+|+.|-+++.. ++. ++. ..+ .+-|+-. ...+|+.|...+
4730 T Consensus 460 sC~l~y~~pa~~vn~t~p~~y~yi~~~~~~~~-----~~~-~~~~~~~~~-~~~cpc~~~~~~~~~~~~~~~~~~~~~~~ 532 (1323)
4731 T 5X5F_B 460 TCLILATVPHNLTTITKPLKYSYINKCSRLLS-----DDR-TEVPQLVNA-NQYSPCVSIVPSTVWEDGDYYRKQLSPLE 532 (1323)
4732 T ss_dssp EEEEEEECCSSCCSBCCCSEEEEEEEEEEECT-----TSS-CEEECCCCT-TSCCTTTTTSCSSCSSTTCEEEEECCTTT
4733 T ss_pred ccEEEEEcCccccccCCCccceeeeeeeccCC-----CCC-Ccchhhccc-cccCCCCccCCccccCCCCcccccccccc
4734 Confidence 999999955533322 445666555555433 222 222 111 1111100 012344443222
4735
4736
4737 Q sp|P0DTC2|SPIK 496 --GFQP----TNGVGYQPYRVVVLSFELLHAPATVCGP-----KKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQ 564 (1273)
4738 Q Consensus 496 --gfqp----tngvgyqpyrvvvlsfellhapatvcgp-----kkstnlvknkcvnfnfngltgtgvltesnkkflpfqq 564 (1273)
4739 |..+ ..++++|++.++|++++..+.++|||++ |.+|.++.++||++|+.|+||+||++|++..+..+|.
4740 T Consensus 533 ~~~~~~~~~~~~~~~~~~~g~~Vis~k~~~~s~tVCp~~~d~~~~~T~~~l~vCV~YnlYGiTGtGVf~~sn~~~~~~Q~ 612 (1323)
4741 T 5X5F_B 533 GGGWLVASGSTVAMTEQLQMGFGITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQR 612 (1323)
4742 T ss_dssp TSSEEEEEEEEEECCSSCEEEEEEECCCCSSCCCEEECC------CCSSSCCCSSCEECSSCCCCCCCEECCCCSCSSSC
4743 T ss_pred CCchhcccccccccccceeEEEEEEeEcCCCccccCCCcccCCcCCcchhcCceeeEEecceeeeEEEEecCccccccee
4744 Confidence 2233 4589999999999999999999999988 5668999999999999999999999999999999999
4745
4746
4747 Q sp|P0DTC2|SPIK 565 FGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRV--YSTGSNV 642 (1273)
4748 Q Consensus 565 fgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrv--ystgsnv 642 (1273)
4749 |..|-.+-..+.|| +++++.+|+||..|+|||+++++ ++..|+||++++|.+|...+|..+.+|.|+. ++...+.
4750 T Consensus 613 f~yds~Gnl~gfk~-~tg~vY~I~PC~s~~VSViy~~~--s~e~AlLf~~v~C~~v~t~~~~~~~~~~~~~~~~~~~~~~ 689 (1323)
4751 T 5X5F_B 613 FVYDAYQNLVGYYS-DDGNYYCLRACVSVPVSVIYDKE--TKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGP 689 (1323)
4752 T ss_dssp CCBCSSSCBCCCCC-SSSCCEECCCCCBCCCBEECCTT--TTCCCCBCSSCCTTTCCTTCTTBSCSSSSCCC--------
4753 T ss_pred EEEcCCCCEEEEEe-CCCCEEEEeeceeeceeEEEeCC--CCceEEEeCCccccceecceeeecCCCchhcccccCCCCC
4754 Confidence 99999999999999 99999999999999999999998 7799999999999999999999999999998 7778889
4755
4756
4757 Q sp|P0DTC2|SPIK 643 FQTRAGCLIGAEHVNN-SYECDIPIGAGICASYQTQTNS-PRRARSVAS-QSII--AYTMSLGAENSVAYSNNSIAIPTN 717 (1273)
4758 Q Consensus 643 fqtragcligaehvnn-syecdipigagicasyqtqtns-prrarsvas-qsii--aytmslgaensvaysnnsiaiptn 717 (1273)
4759 |||-+||++||++.+. .+|||+|+|+|+|+.|.+...+ +|+.|++.. ..+. +|+|.+-. .++.+++..|.||+|
4760 T Consensus 690 fdT~~GCVvnA~n~t~~V~~C~lplG~glC~~y~~~s~~~~r~~~~~~~~~~l~~~~y~~p~~~-~~~~~~~~~i~IP~n 768 (1323)
4761 T 5X5F_B 690 LQTPVGCVLGLVNSSLFVEDCKLPLGQSLCALPDTPSTLTPRSVSSVPGEMRLASIAFNHPIQV-DQLNSSYFKLSIPTN 768 (1323)
4762 T ss_dssp ---CBCCSSSCBSSCCCCCCCCCCCTTCCSSSCCCCCC------------CCCCCCCCCCCCCC-CCCCSSCCEEEECCC
4763 T ss_pred CCCccceeeecccCCCceeeCCCCCCcceecCCCCcCcCccccccCCCCceEEEEEeecCCeee-cccCCCCeeEEcccc
4764 Confidence 9999999999999988 8999999999999999988755 344444443 3344 67777765 778889999999999
4765
4766
4767 Q sp|P0DTC2|SPIK 718 FTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF 797 (1273)
4768 Q Consensus 718 ftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf 797 (1273)
4769 |||+|++|-+.++|.|.+|||.+|+||++.+|.+||.|||+||..+|+||.|.+.++|.+..+++..+++-++.+-+..|
4770 T Consensus 769 Ft~~v~~EyiQ~~~~kv~iDC~~YVC~~~~~C~~lL~qYgs~C~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~~~~~~f 848 (1323)
4771 T 5X5F_B 769 FSFGVTQEYIQTTIQKVTVDCKQYVCNGFQKCEQLLREYGQFCSKINQALHGANLRQDDSVRNLFASVKSSQSSPIIPGF 848 (1323)
4772 T ss_dssp CCCCCCCCBCCCCCCCCEECTTSSSSSSCHHHHHHHHTSHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCSSCCCCCCSCC
4773 T ss_pred eEEEEEEEEEeecCCceEEechhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHhhhccHHHHHHHHhccccccCCCcCCC
4774 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999998888887
4775
4776
4777 Q sp|P0DTC2|SPIK 798 -GGFNFSQILPDPS---KPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDI--AARDLICAQKFNGLTVLPPLLTDEMIA 871 (1273)
4778 Q Consensus 798 -ggfnfsqilpdps---kpskrsfiedllfnkvtladagfikqygdclgdi--aardlicaqkfngltvlpplltdemia 871 (1273)
4779 |+|||+.+||.+. ++++||+||||||+||.+.|.||.+.|+.|.... ..|||+|||.+||+.||||..++||.+
4780 T Consensus 849 ~~~~N~s~ll~~~~~~~~~~~RS~iEDLLF~KV~t~g~G~~~~Y~~C~~g~~~~i~DL~CAQ~yNGi~VLP~v~~~~le~ 928 (1323)
4781 T 5X5F_B 849 GGDFNLTLLEPVSISTGSRSARSAIEDLLFDKVTIADPGYMQGYDDCMQQGPASARDLICAQYVAGYKVLPPLMDVNMEA 928 (1323)
4782 T ss_dssp BTTBCCTTSCCC--------CCCHHHHHHHHSSCCCCCCSSSHHHHHHTC--------CCTTTSCSEECCCCSSCHHHHH
4783 T ss_pred CCCcccceeccCCCCCCCccceeHHHHHhcceeeeCCCCcccChhhhcccCCccHHHHhheeEeCCEeecCCcCCHhHHH
4784 Confidence 5799999999876 3468999999999999999999999999999554 899999999999999999999999999
4785
4786
4787 Q sp|P0DTC2|SPIK 872 QYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDV 951 (1273)
4788 Q Consensus 872 qytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdv 951 (1273)
4789 +|+.+++.+....||++|..++..|||++++.+|+|++++++++|.+|||.|||.||.|||.||+.+.++++||.|+|++
4790 T Consensus 929 ~yt~SdvG~l~~~r~e~G~tsaaaIpfs~~Vy~RLN~l~~~~~vL~~nq~~Ia~sFN~aIg~iq~gf~t~~~Al~kIq~v 1008 (1323)
4791 T 5X5F_B 929 AYTSSLLGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDA 1008 (1323)
4792 T ss_dssp HHHHHHHHHHHHHTTCSCCC-CCCCCHHHHHHHHHHHSSCCCHHHHHTTCCSHHHHHHHHHHHHHCCTTTCTTHHHHHHH
4793 T ss_pred HHHHHHHHhhhcccccccCCccccCCchHHHHHHHHhhhchHHHHHHHHHHHHHHHHHHHHHHhhccccHHHHHHHHHHH
4794 Confidence 99999999888889999999999999999999999999999999999999999999999999999999999999999999
4795
4796
4797 Q sp|P0DTC2|SPIK 952 VNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSE 1031 (1273)
4798 Q Consensus 952 vnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmse 1031 (1273)
4799 ||+++++|++|..||+.|||||||.+++|+.|||++||++|+||||+|||.+|.+||+|||+|++|+|+|+.||..|+.|
4800 T Consensus 1009 VN~~~~als~L~~qLn~~FgAISssi~gI~~RLd~lEa~iqvdrlInGRL~aLn~~Vtq~l~~~~~v~~sr~LA~qKiNE 1088 (1323)
4801 T 5X5F_B 1009 VNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQIDRLINGRLTTLNAFVAQQLVRSESAALSAQLAKDKVNE 1088 (1323)
4802 T ss_dssp HHHHHCCCCCHHHHHSSSCSSSCSSSTTTTTSSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
4803 T ss_pred HHHHHHHHHHHHHHHhhhcccchhcHhHHHHHHHHHHHHhCCChhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4804 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4805
4806
4807 Q sp|P0DTC2|SPIK 1032 CVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHD---GKAHFPREGVFVSNG-----THWF 1103 (1273)
4808 Q Consensus 1032 cvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichd---gkahfpregvfvsng-----thwf 1103 (1273)
4809 ||..||+|.+|||.|.|++|+||.||+|++|+|.+|+|.+.++.+++|.+|++ +++..|+.|.|+.+. .+|+
4810 T Consensus 1089 CVKSQS~R~gFCGnG~Hi~S~~q~AP~Gi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~~~~g~~~~~~~~~~~~~~~ 1168 (1323)
4811 T 5X5F_B 1089 CVKAQSKRSGFCGQGTHIVSFVVNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANPTNCIAPVNGYFIKTNNTRIVDEWS 1168 (1323)
4812 T ss_dssp CCCSCCSSSTTSCSSSEEECCBCCCSSSCBBCCEECCCCCCEEEECCSCCCCSSCCCCCCSSSCCCCSSSSCCCCSSSCC
4813 T ss_pred HHHhcccccCCCCCCeeeEEeeeccCCeEEEEEEEecccceeEEEEEEEEeecCCCCceeeccCeEEEEeCCceeeceEE
4814 Confidence 99999999999999999999999999999999999999999999999999996 688999999999876 5699
4815
4816
4817 Q sp|P0DTC2|SPIK 1104 VTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPL--QPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQK 1181 (1273)
4818 Q Consensus 1104 vtqrnfyepqiittdntfvsgncdvvigivnntvydpl--qpeldsfkeeldkyfknhtspdvdlgdisginasvvniqk 1181 (1273)
4819 +|.|++|+|..||.+|+. --.|+|...-+|+++..|+ +|+...|+|||+|+|||+++...|+.++..+|+++.|++.
4820 T Consensus 1169 ~T~r~~y~P~~~t~~~v~-i~sc~V~y~n~~~~~l~~~v~~p~yiDfn~el~~~~~n~~~~~p~l~~l~~fN~T~LNLt~ 1247 (1323)
4821 T 5X5F_B 1169 YTGSSFYAPEPITSLNTK-YVAPQVTYQNISTNLPPPLLGNSTGIDFQDELDEFFKNVSTSIPNFGSLTQINTTLLDLTY 1247 (1323)
4822 T ss_dssp CCCCSSSCCCCCCCSSTT-SCC----------------------------------------------------------
4823 T ss_pred EeCCccccCccCCCCCEE-EECCcceEEecCCCCCCCccCCCCCCChHHHHHHHHhcCCCCCCCCCchhcceecccchHH
4824 Confidence 999999999999999955 5778999999999999984 6899999999999999999988888889999999999999
4825
4826
4827 Q sp|P0DTC2|SPIK 1182 EIDRLNEVAKNLNESLIDLQELGKYEQYIKWPWYIWLGF 1220 (1273)
4828 Q Consensus 1182 eidrlnevaknlneslidlqelgkyeqyikwpwyiwlgf 1220 (1273)
4829 ||++|+|+.|+||+++|||++|++||+|||||||+--|-
4830 T Consensus 1248 EI~~Lq~~i~~LN~s~idLe~Ln~~e~YiKW~~~~~~~~ 1286 (1323)
4831 T 5X5F_B 1248 EMLSLQQVVKALNESYIDLKELGNYTYYNKEFRLVPRGS 1286 (1323)
4832 T ss_dssp ---------------------------------------
4833 T ss_pred HHHHHHHHHHHHHhccCCHHHhCceeeeEeeeeecCCCC
4834 Confidence 999999999999999999999999999999999987653
4835
4836
4837 No 6
4838 >6VSJ_A Spike glycoprotein, Carcinoembryonic antigen-related cell; MHV spike, CEACAM1a, Complex, Glycoprotein; HET: NAG; 3.94A {Murine coronavirus (strain A59)}
4839 Probab=100.00 E-value=2.1e-195 Score=1649.54 Aligned_cols=1145 Identities=30% Similarity=0.512 Sum_probs=889.4 Template_Neff=4.000
4840
4841 Q sp|P0DTC2|SPIK 9 PLVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI--HVSGTNGTKR 78 (1273)
4842 Q Consensus 9 plvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai--hvsgtngtkr 78 (1273)
4843 ++....|...-...-++ |.++ -+-.+|+||||..++|+..+-.|+||.+.-++.+-+-.- |... .--.
4844 T Consensus 22 ~i~~~~C~~~~~~~~~~~~~~~~s~~~idvs~~~G~yYPd~rvysN~TlL~qGLFP~~gs~~~~Y~~sgt~~~s--~~~~ 99 (1275)
4845 T 6VSJ_A 22 YIGDFRCIQLVNSNGANVSAPSISTETVEVSQGLGTYYVLDRVYLNATLLLTGYYPVDGSKFRNLALRGTNSVS--LSWF 99 (1275)
4846 T ss_dssp CCSSBCCCCCSEECCCCCCCCCCCSCBCCCTTSTTCBCCTTCBCCSCCCEEEEEEECTTCBCCBCCCEESSEEC--GGGS
4847 T ss_pred cccCcceeEeecCCCCCCCCCCCcceeeeeecceeEEEeCCeEEeceeeeeccccCCCCCceeeEEeeccCCCC--cccc
4848 Confidence 34555677653333333 3444 345689999999999999999999999998887654222 2222 1346
4849
4850
4851 Q sp|P0DTC2|SPIK 79 FDNPVLPFNDGVYFASTEKSNI--------IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNK 150 (1273)
4852 Q Consensus 79 fdnpvlpfndgvyfasteksni--------irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnk 150 (1273)
4853 +++++.||+||+++...+.+|- -..++||+|.+..+++++|+++-+...|.+|.|..|..|...+++.-+|.
4854 T Consensus 100 y~~~~~~F~dGIfVkV~~~kn~t~~~~~~~ypa~~fGSTF~Nts~tvVI~P~~~~r~itvCq~~vC~~p~~~~~p~~g~~ 179 (1275)
4855 T 6VSJ_A 100 QPPYLNQFNDGIFAKVQNLKTSTPSGATAYFPTIVIGSLFGYTSYTVVIEPYNGVIMASVCQYTICQLPYTDCKPNTNGN 179 (1275)
4856 T ss_dssp STTTSCCCSSCEEEEEECCGGGSCTTCCCSSCCEEEESSCSTTSCEEEECEETTEECCEEECCCBBSSCCEESSCCCSSC
4857 T ss_pred cCCcccccCCcEEEEeeeeccCCCCcchhccceeEEecccCCCceEEEEeCCCceeEeEEEEEEEcCCCeeEEccCCCCC
4858 Confidence 7788999999999998887765 35678999999999999999999999999999999999999888744332
4859
4860
4861 Q sp|P0DTC2|SPIK 151 SWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLV 227 (1273)
4862 Q Consensus 151 swmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplv 227 (1273)
4863 +..+ ++. ....+|+|.|. +.|-+|... ..|- |.|+..||.|-+|..+...+. ..-+| |...+.+.
4864 T Consensus 180 ~~~~--~~~-~d~~nc~f~~~-~nfT~d~~~--~~~~----~~F~~~dG~fy~Yyad~~~~~~f~f~~~~-~~~~~~yy- 247 (1275)
4865 T 6VSJ_A 180 KLIG--FWH-TDVKPPICVLK-RNFTLNVNA--DAFY----FHFYQHGGTFYAYYADKPSATTFLFSVYI-GDILTQYY- 247 (1275)
4866 T ss_dssp TTCC--SSB-CCCSCCCEEEE-CCEECCTTC--SEEE----EEBCEETTEECCEECSSSSCBEECCCCCC-SSCCCEEE-
4867 T ss_pred ceee--ece-ecCCCCEEEEe-eeeccCccc--ceee----EEEEEcCCeEEEEEECCCcCcceeecccc-cceeceeE-
4868 Confidence 3322 233 67889999764 455444322 1221 999999999988876644332 11222 33333333
4869
4870
4871 Q sp|P0DTC2|SPIK 228 DLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFT 307 (1273)
4872 Q Consensus 228 dlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksft 307 (1273)
4873 .+-|+..++ .+.+ ..++|||++|.+|+|||+|++||.||+||||+-|+++|-||..+||.
4874 T Consensus 248 ---------------v~~~~~~~~---~~~~--~~~~~~v~~L~~~~~ll~fd~~G~i~~avDC~~~~~~el~C~~~sf~ 307 (1275)
4875 T 6VSJ_A 248 ---------------VLPFICNPT---AGST--FAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTQSML 307 (1275)
4876 T ss_dssp ---------------ECCEECCCS---SCSC--CCCEEEEEEEEEEEEECCBCSSSCBCCCBCTTSCHHHHHHHHHTSSS
4877 T ss_pred ---------------EeeeeecCC---CCCC--cccEEEEEeccceeEEEEecCCCeEeEEEecccCccceeeeEecccc
4878 Confidence 233444333 2223 67899999999999999999999999999999999999999999999
4879
4880
4881 Q sp|P0DTC2|SPIK 308 VEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKL 387 (1273)
4882 Q Consensus 308 vekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl 387 (1273)
4883 +++|+|++|+||+||....+|.++.+..|+|.++++|.++.++|.|.|+.++||..|+++|++..++++|+||||+|.||
4884 T Consensus 308 ~~~GVY~~s~y~a~p~~~v~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~~~nCnfn~s~Ll~~~~~~~f~C~~ispskl 387 (1275)
4885 T 6VSJ_A 308 PSTGVYELSGYTVQPVGVVYRRVANLPACNIEEWLTARSVPSPLNWERKTFQNCNFNLSSLLRYVQAESLFCNNIDASKV 387 (1275)
4886 T ss_dssp CCSSCEECCCCCCCCCCCCCCCCCCCCBCCTHHHHTCSEEECTTSCEEEEECSCBCCHHHHHHHSEEEECCBSSCCTTTS
4887 T ss_pred CCCceeecCCeEEEeeeEEEEecCCCCCCCHHHHHhcCCCCCchhcEEeEEecCCCCHHHHHhheeeccceecCCCHHHH
4888 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4889
4890
4891 Q sp|P0DTC2|SPIK 388 NDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK----VGGNYNYLYRLFRKSNLKP 463 (1273)
4892 Q Consensus 388 ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk----vggnynylyrlfrksnlkp 463 (1273)
4893 .++||..|++|.|.|..+..++++||++|-|++||||+|+||+||+++|+-...+.. --++||+-|+.-++..++|
4894 T Consensus 388 ~~~CfssvtiD~F~ip~~~~~~l~~g~~g~i~~yNYkl~~~~~~C~l~~~~~~~~~~~t~~np~~~~~~~~~~~~~~f~~ 467 (1275)
4895 T 6VSJ_A 388 YGRCFGSISVDKFAVPRSRQVDLQLGNSGFLQTANYKIDTAATSCQLHYTLPKNNVTINNHNPSSWNRRYGFNDAGVFGK 467 (1275)
4896 T ss_dssp TTCCBSEEEEEEECCCSTTGGGGSTTCCSSHHHHTCCCCSSSCEEECEEEECTTTCEEECCCCCHHHHHHSCCTTTTTTT
4897 T ss_pred cccccCeeEEEEEeccchhceeecCCCCcHhHhccccCCCCCCceEEEEEcCcccccccCCCCccchhcccccccccccC
4898 Confidence 999999999999999999999999999999999999999999999999996543322 2357888888888899999
4899
4900
4901 Q sp|P0DTC2|SPIK 464 FERDISTEIY--QAGSTPCNG--V------------------EGFNCYF------------PLQSYGFQPTNGVGYQPY- 508 (1273)
4902 Q Consensus 464 ferdisteiy--qagstpcng--v------------------egfncyf------------plqsygfqptngvgyqpy- 508 (1273)
4903 +++|..-..+ ..+.+-|+. . .|..|+- |..+---+|+..+||+++
4904 T Consensus 468 ~~~dvvy~~~~~~~~~~~cpC~~~~~~~~ct~~~~~~~~~~~~~~~c~g~~vi~~~~g~~~~~~~c~c~~~af~gws~d~ 547 (1275)
4905 T 6VSJ_A 468 NQHDVVYAQQCFTVRSSFCPCAQPDIVSPCTTQTKPKSAFVNVGDHCEGLGVLEDNCGNADPHKGCICANNSFIGWSHDT 547 (1275)
4906 T ss_dssp CSSEEEEESCBBCCCSCCCSCC-----------CCCCBCCCCTTCCCCCBEECTTSEECCCSSSSCEECTTCEESEEEEE
4907 T ss_pred cccceeeccccccCCCCCCCCCCCCcCCCCCCCCCCccceeccccccceeEEeeccCCCCCCCCCccccCCcccccCccc
4908 Confidence 9999876533 233333330 0 1112211 001111256777888888
4909
4910
4911 Q sp|P0DTC2|SPIK 509 -----RVVVLSFELLHA--PATVCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVR 577 (1273)
4912 Q Consensus 509 -----rvvvlsfellha--patvcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavr 577 (1273)
4913 |++|+|++||++ ++|||+. +..++++.++||++|..|.||+||+++.+ ..+-.+|.+..+.+.-..++|
4914 T Consensus 548 c~~~~r~~i~~~~~ln~~~s~tvCp~~~~~~~t~I~ln~CVdYNIYGitGtGVItnvt~~~~~~~qgL~yS~sG~L~~FK 627 (1275)
4915 T 6VSJ_A 548 CLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVVTGICVKYDLYGITGQGVFKEVKADYYNSWQTLLYDVNGNLNGFR 627 (1275)
4916 T ss_dssp CEETTEEEEEEEEEEESTTCCSBBCSSSCCCCCCCCCSSCEEEEETTEEEEEEEECCCCCCCCSSCCCEECTTSCEEEEE
4917 T ss_pred cccCCceeeeeeeeccCCCCCCCCCCcCCCCCceEEeCeEEEEEeCCCeeEEEEEecCCcccccCccEEEeCCCCEEEEE
4918 Confidence 999999999998 8999998 34689999999999999999999999944 444466778888889999999
4919
4920
4921 Q sp|P0DTC2|SPIK 578 DPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN 657 (1273)
4922 Q Consensus 578 dpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn 657 (1273)
4923 ++.++++..|+||..+.++++..|. +...|+++..++|+++....+....+| .+.|+|-.||+++++|.+
4924 T Consensus 628 n~ttg~~YsV~PC~~v~qQvVV~~~--sivgalls~n~~cs~~~~n~~~~~~~~--------~~~~~t~~gCv~~a~~~t 697 (1275)
4925 T 6VSJ_A 628 DLTTNKTYTIRSCYSGRVSAAFHKD--APEPALLYRNINCSYVFSNNISREENP--------LNYFDSYLGCVVNADNRT 697 (1275)
4926 T ss_dssp CTTTCCEEEEECCCCCEEECCCCTT--CSSCCEEETTCCHHHHHHTTCCSSCCC--------SCCEECSSSEECSCSEEE
4927 T ss_pred cCCCCCEEEEEeCceeceeEEEeCC--CceeEEEEeccceeceeeccceeeeCC--------CcceeccccceeccccCC
4928 Confidence 9999999999999999999999876 567789999999999886444333333 344999999999999887
4929
4930
4931 Q sp|P0DTC2|SPIK 658 N--SYECDIPIGAGICASYQTQTNSPRRARSVASQ-SIIA---YT-MSLGAENSVAYSNNSIAIPTNFTISVTTEILPVS 730 (1273)
4932 Q Consensus 658 n--syecdipigagicasyqtqtnsprrarsvasq-siia---yt-mslgaensvaysnnsiaiptnftisvtteilpvs 730 (1273)
4933 + ..+|++|.|.|||+.+..-.-.+ |++..+ .+.. +. +..........+...|.||+||||+|++|-++++
4934 T Consensus 698 ~~~~~~c~~~~g~giC~dg~~~~~~~---~~~~~~~~~~~~~~~~~~~~~~s~~~~~~~~~i~IP~nFtlsv~~EyiQt~ 774 (1275)
4935 T 6VSJ_A 698 DEALPNCDLRMGAGLCVDYSKSRRAH---RSVSTGYRLTTFEPYTPMLVNDSVQSVDGLYEMQIPTNFTIGHHEEFIQTR 774 (1275)
4936 T ss_dssp EEEESSCSEEETTTEEEEECTTTCSS---SSSTTSEEEEEECSCCCCBCCCSCSSSCCBCSCCBCCCCEEECCEEECCCC
4937 T ss_pred CCcCCCCCCccceEEccCcccceecc---cccCCCceeecccCCcccccCCCCCccCcceEEEccCceEEEEEEEEeecC
4938 Confidence 5 68999999999999998833222 221111 1111 11 1111125566777899999999999999999999
4939
4940
4941 Q sp|P0DTC2|SPIK 731 MTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTP-P----I-KDFGGFNFSQ 804 (1273)
4942 Q Consensus 731 mtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktp-p----i-kdfggfnfsq 804 (1273)
4943 |.|.+|||.+|+||++.+|.+||.|||+||..+|+||.|.+..+|....++++.+++.++.+ + | ...|+|||+.
4944 T Consensus 775 ~~kVsIDCa~YVC~g~~rC~~LL~QYgsfC~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~s~~~~~~~~~~~~~fN~s~ 854 (1275)
4945 T 6VSJ_A 775 SPKVTIDCAAFVCGDNTACRQQLVEYGSFCVNVNAILNEVNNLLDNMQLQVASALMQGVTISSRLPDGISGPIDDINFSP 854 (1275)
4946 T ss_dssp CCEEECCHHHHHSCSSHHHHHHHGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCBCC----------------
4947 T ss_pred CCCeEEEhhheecCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccccccCCCCCCCCCCCccchh
4948 Confidence 99999999999999999999999999999999999999999999999999999999998875 2 2 4456799999
4949
4950
4951 Q sp|P0DTC2|SPIK 805 ILPD-----------PSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQY 873 (1273)
4952 Q Consensus 805 ilpd-----------pskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqy 873 (1273)
4953 +||. |+++++||+|||||||||+.+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||+|.|
4954 T Consensus 855 ll~~~~~~~~~~~~~~~~~~~RSaIEDLLF~KV~t~glG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpvvd~~~~amY 934 (1275)
4955 T 6VSJ_A 855 LLGCIGSTCAEDGNGPSAIRGRSAIEDLLFDKVKLSDVGFVEAYNNCTGGQEVRDLLCVQSFNGIKVLPPVLSESQISGY 934 (1275)
4956 T ss_dssp ------CCSSCCSSSTTTTTTTTHHHHHHHHHCSSCTTHHHHHHHHHHTTSSTTSSHHHHHHTTCEEECCSSCHHHHHHH
4957 T ss_pred hcccccCCcccCCCCCCccCcccHHHHHHcceeeecCCchHHHHHhccCCcchHHhhcccccCcEEEeCCCCCHHHHHHH
4958 Confidence 9986 56668999999999999999999999999999999999999999999999999999999999999
4959
4960
4961 Q sp|P0DTC2|SPIK 874 TSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVN 953 (1273)
4962 Q Consensus 874 tsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvn 953 (1273)
4963 |++|++|....|||+ |..||||+||.||+||+|+||+||.||||+|||.||.||+.||+.++++++||.|+|||||
4964 T Consensus 935 TasL~g~m~~gg~Ta----aaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~iq~~f~~~~~Al~kiQ~VVN 1010 (1275)
4965 T 6VSJ_A 935 TTGATAAAMFPPWSA----AAGVPFSLSVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQDGFDATNSALGKIQSVVN 1010 (1275)
4966 T ss_dssp HHHHHHTTSCSSSCS----STTCCHHHHHHHHGGGTSCHHHHTTHHHHHHHHHHHHHHHHHHHHHSSCCHHHHHHHHHHH
4967 T ss_pred HHHHHHHhhcccchh----cccCchHHHHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4968 Confidence 999999999999997 5568999999999999999999999999999999999999999999999999999999999
4969
4970
4971 Q sp|P0DTC2|SPIK 954 QNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECV 1033 (1273)
4972 Q Consensus 954 qnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecv 1033 (1273)
4973 ++++||++|++||+.|||||||.++||++|||++||++||||||+|||.+|++||+|||+|++|+|||+.||..||.|||
4974 T Consensus 1011 ~q~~aL~~L~~qL~~nFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qKINECV 1090 (1275)
4975 T 6VSJ_A 1011 ANAEALNNLLNQLSNRFGAISASLQEILTRLEAVEAKAQIDRLINGRLTALNAYISKQLSDSTLIKVSAAQAIEKVNECV 1090 (1275)
4976 T ss_dssp HHHHHHHHHHHGGGSCCSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
4977 T ss_pred HHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
4978 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
4979
4980
4981 Q sp|P0DTC2|SPIK 1034 LGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEP 1112 (1273)
4982 Q Consensus 1034 lgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyep 1112 (1273)
4983 ..||+|.+|||.|.|++|+||.||+|++|+|++|+|.+.++.+++|.+|+++ ++..|+.|+|+.+...|++|.|++|||
4984 T Consensus 1091 KSQS~R~gFCGnGtHi~Si~q~APnGi~FlH~~y~Pt~~~~V~a~~GlC~~~~~~~~p~~g~fv~~n~~~~iT~r~~Y~P 1170 (1275)
4985 T 6VSJ_A 1091 KSQTTRINFCGNGNHILSLVQNAPYGLYFIHFSYVPISFTTANVSPGLCISGDRGLAPKAGYFVQDDGEWKFTGSSYYYP 1170 (1275)
4986 T ss_dssp CSCCSSSSCSSSSCCCCCCEECCTTSCEEECCEEECCSCCCCBCCTTCCSCCCSSSCCCCSCCCBCSSSSBCCCSSBCCC
4987 T ss_pred hcCCCcccccCCCeEEEEeeeccCCeEEEEEEEecccceEEEEEEeeeEecCCceEEecCeEEEecCCEEEEeccCcccC
4988 Confidence 9999999999999999999999999999999999999999999999999994 899999999999988999999999999
4989
4990
4991 Q sp|P0DTC2|SPIK 1113 QIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLG-DISGINASVVN----IQKEIDRLN 1187 (1273)
4992 Q Consensus 1113 qiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlg-disginasvvn----iqkeidrln 1187 (1273)
4993 ..||.+|...-..|||...-+|+++..|..|++..|+|||+|+|||+++...|++ |++.+|+++++ ++.++++|+
4994 T Consensus 1171 r~it~~d~v~~~sC~v~y~n~~~~~l~~~~p~~~df~~el~~~~~n~~~~~p~~~~~~~~~N~t~L~Ei~~l~~~~~~l~ 1250 (1275)
4995 T 6VSJ_A 1171 EPITDKNSVIMSSCAVNYTKAPEVFLNTSIPNPPDFKEELDKWFKNQTSIAPDLSLDFEKLNVTLIKRMKQIEDKIEEIE 1250 (1275)
4996 T ss_dssp CSSCCC--------------------------------------------------------------------------
4997 T ss_pred CCCCccceEEeeccccEEEEcccccCCCCCCCCCChHHHHHHHHhcCCCCCCCcCCCHHHccHHHHHHHHHHHHHHHHHH
4998 Confidence 9999999999999999999999999999999999999999999999999666664 38899999986 666666666
4999
5000
5001 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELG 1204 (1273)
5002 Q Consensus 1188 evaknlneslidlqelg 1204 (1273)
5003 ++.++||.++.++..+.
5004 T Consensus 1251 ~~i~~in~~~~~~~~~~ 1267 (1275)
5005 T 6VSJ_A 1251 SKQKKIENEIARIKKIK 1267 (1275)
5006 T ss_dssp -----------------
5007 T ss_pred HHHHHHHHHHHHHHHhc
5008 Confidence 66777777766665543
5009
5010
5011 No 7
5012 >6VSJ_C Spike glycoprotein, Carcinoembryonic antigen-related cell; MHV spike, CEACAM1a, Complex, Glycoprotein; HET: NAG; 3.94A {Murine coronavirus (strain A59)}
5013 Probab=100.00 E-value=2.1e-195 Score=1649.54 Aligned_cols=1145 Identities=30% Similarity=0.512 Sum_probs=889.4 Template_Neff=4.000
5014
5015 Q sp|P0DTC2|SPIK 9 PLVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI--HVSGTNGTKR 78 (1273)
5016 Q Consensus 9 plvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai--hvsgtngtkr 78 (1273)
5017 ++....|...-...-++ |.++ -+-.+|+||||..++|+..+-.|+||.+.-++.+-+-.- |... .--.
5018 T Consensus 22 ~i~~~~C~~~~~~~~~~~~~~~~s~~~idvs~~~G~yYPd~rvysN~TlL~qGLFP~~gs~~~~Y~~sgt~~~s--~~~~ 99 (1275)
5019 T 6VSJ_C 22 YIGDFRCIQLVNSNGANVSAPSISTETVEVSQGLGTYYVLDRVYLNATLLLTGYYPVDGSKFRNLALRGTNSVS--LSWF 99 (1275)
5020 T ss_dssp CCSSBCCCCCSEECCCCCCCCCCCSCBCCCTTSTTCBCCTTCBCCSCCCEEEEEEECTTCBCCBCCCEESSEEC--GGGS
5021 T ss_pred cccCcceeEeecCCCCCCCCCCCcceeeeeecceeEEEeCCeEEeceeeeeccccCCCCCceeeEEeeccCCCC--cccc
5022 Confidence 34555677653333333 3444 345689999999999999999999999998887654222 2222 1346
5023
5024
5025 Q sp|P0DTC2|SPIK 79 FDNPVLPFNDGVYFASTEKSNI--------IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNK 150 (1273)
5026 Q Consensus 79 fdnpvlpfndgvyfasteksni--------irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnk 150 (1273)
5027 +++++.||+||+++...+.+|- -..++||+|.+..+++++|+++-+...|.+|.|..|..|...+++.-+|.
5028 T Consensus 100 y~~~~~~F~dGIfVkV~~~kn~t~~~~~~~ypa~~fGSTF~Nts~tvVI~P~~~~r~itvCq~~vC~~p~~~~~p~~g~~ 179 (1275)
5029 T 6VSJ_C 100 QPPYLNQFNDGIFAKVQNLKTSTPSGATAYFPTIVIGSLFGYTSYTVVIEPYNGVIMASVCQYTICQLPYTDCKPNTNGN 179 (1275)
5030 T ss_dssp STTTSCCCSSCEEEEEECCGGGSCTTCCCSSCCEEEESSCSTTSCEEEECEETTEECCEEECCCBBSSCCEESSCCCSSC
5031 T ss_pred cCCcccccCCcEEEEeeeeccCCCCcchhccceeEEecccCCCceEEEEeCCCceeEeEEEEEEEcCCCeeEEccCCCCC
5032 Confidence 7788999999999998887765 35678999999999999999999999999999999999999888744332
5033
5034
5035 Q sp|P0DTC2|SPIK 151 SWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLV 227 (1273)
5036 Q Consensus 151 swmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplv 227 (1273)
5037 +..+ ++. ....+|+|.|. +.|-+|... ..|- |.|+..||.|-+|..+...+. ..-+| |...+.+.
5038 T Consensus 180 ~~~~--~~~-~d~~nc~f~~~-~nfT~d~~~--~~~~----~~F~~~dG~fy~Yyad~~~~~~f~f~~~~-~~~~~~yy- 247 (1275)
5039 T 6VSJ_C 180 KLIG--FWH-TDVKPPICVLK-RNFTLNVNA--DAFY----FHFYQHGGTFYAYYADKPSATTFLFSVYI-GDILTQYY- 247 (1275)
5040 T ss_dssp TTCC--SSB-CCCSCCCEEEE-CCEECCTTC--SEEE----EEBCEETTEECCEECSSSSCBEECCCCCC-SSCCCEEE-
5041 T ss_pred ceee--ece-ecCCCCEEEEe-eeeccCccc--ceee----EEEEEcCCeEEEEEECCCcCcceeecccc-cceeceeE-
5042 Confidence 3322 233 67889999764 455444322 1221 999999999988876644332 11222 33333333
5043
5044
5045 Q sp|P0DTC2|SPIK 228 DLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFT 307 (1273)
5046 Q Consensus 228 dlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlksft 307 (1273)
5047 .+-|+..++ .+.+ ..++|||++|.+|+|||+|++||.||+||||+-|+++|-||..+||.
5048 T Consensus 248 ---------------v~~~~~~~~---~~~~--~~~~~~v~~L~~~~~ll~fd~~G~i~~avDC~~~~~~el~C~~~sf~ 307 (1275)
5049 T 6VSJ_C 248 ---------------VLPFICNPT---AGST--FAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTQSML 307 (1275)
5050 T ss_dssp ---------------ECCEECCCS---SCSC--CCCEEEEEEEEEEEEECCBCSSSCBCCCBCTTSCHHHHHHHHHTSSS
5051 T ss_pred ---------------EeeeeecCC---CCCC--cccEEEEEeccceeEEEEecCCCeEeEEEecccCccceeeeEecccc
5052 Confidence 233444333 2223 67899999999999999999999999999999999999999999999
5053
5054
5055 Q sp|P0DTC2|SPIK 308 VEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKL 387 (1273)
5056 Q Consensus 308 vekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptkl 387 (1273)
5057 +++|+|++|+||+||....+|.++.+..|+|.++++|.++.++|.|.|+.++||..|+++|++..++++|+||||+|.||
5058 T Consensus 308 ~~~GVY~~s~y~a~p~~~v~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~~~nCnfn~s~Ll~~~~~~~f~C~~ispskl 387 (1275)
5059 T 6VSJ_C 308 PSTGVYELSGYTVQPVGVVYRRVANLPACNIEEWLTARSVPSPLNWERKTFQNCNFNLSSLLRYVQAESLFCNNIDASKV 387 (1275)
5060 T ss_dssp CCSSCEECCCCCCCCCCCCCCCCCCCCBCCTHHHHTCSEEECTTSCEEEEECSCBCCHHHHHHHSEEEECCBSSCCTTTS
5061 T ss_pred CCCceeecCCeEEEeeeEEEEecCCCCCCCHHHHHhcCCCCCchhcEEeEEecCCCCHHHHHhheeeccceecCCCHHHH
5062 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5063
5064
5065 Q sp|P0DTC2|SPIK 388 NDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK----VGGNYNYLYRLFRKSNLKP 463 (1273)
5066 Q Consensus 388 ndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk----vggnynylyrlfrksnlkp 463 (1273)
5067 .++||..|++|.|.|..+..++++||++|-|++||||+|+||+||+++|+-...+.. --++||+-|+.-++..++|
5068 T Consensus 388 ~~~CfssvtiD~F~ip~~~~~~l~~g~~g~i~~yNYkl~~~~~~C~l~~~~~~~~~~~t~~np~~~~~~~~~~~~~~f~~ 467 (1275)
5069 T 6VSJ_C 388 YGRCFGSISVDKFAVPRSRQVDLQLGNSGFLQTANYKIDTAATSCQLHYTLPKNNVTINNHNPSSWNRRYGFNDAGVFGK 467 (1275)
5070 T ss_dssp TTCCBSEEEEEEECCCSTTGGGGSTTCCSSHHHHTCCCCSSSCEEECEEEECTTTCEEECCCCCHHHHHHSCCTTTTTTT
5071 T ss_pred cccccCeeEEEEEeccchhceeecCCCCcHhHhccccCCCCCCceEEEEEcCcccccccCCCCccchhcccccccccccC
5072 Confidence 999999999999999999999999999999999999999999999999996543322 2357888888888899999
5073
5074
5075 Q sp|P0DTC2|SPIK 464 FERDISTEIY--QAGSTPCNG--V------------------EGFNCYF------------PLQSYGFQPTNGVGYQPY- 508 (1273)
5076 Q Consensus 464 ferdisteiy--qagstpcng--v------------------egfncyf------------plqsygfqptngvgyqpy- 508 (1273)
5077 +++|..-..+ ..+.+-|+. . .|..|+- |..+---+|+..+||+++
5078 T Consensus 468 ~~~dvvy~~~~~~~~~~~cpC~~~~~~~~ct~~~~~~~~~~~~~~~c~g~~vi~~~~g~~~~~~~c~c~~~af~gws~d~ 547 (1275)
5079 T 6VSJ_C 468 NQHDVVYAQQCFTVRSSFCPCAQPDIVSPCTTQTKPKSAFVNVGDHCEGLGVLEDNCGNADPHKGCICANNSFIGWSHDT 547 (1275)
5080 T ss_dssp CSSEEEEESCBBCCCSCCCSCC-----------CCCCBCCCCTTCCCCCBEECTTSEECCCSSSSCEECTTCEESEEEEE
5081 T ss_pred cccceeeccccccCCCCCCCCCCCCcCCCCCCCCCCccceeccccccceeEEeeccCCCCCCCCCccccCCcccccCccc
5082 Confidence 9999876533 233333330 0 1112211 001111256777888888
5083
5084
5085 Q sp|P0DTC2|SPIK 509 -----RVVVLSFELLHA--PATVCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVR 577 (1273)
5086 Q Consensus 509 -----rvvvlsfellha--patvcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavr 577 (1273)
5087 |++|+|++||++ ++|||+. +..++++.++||++|..|.||+||+++.+ ..+-.+|.+..+.+.-..++|
5088 T Consensus 548 c~~~~r~~i~~~~~ln~~~s~tvCp~~~~~~~t~I~ln~CVdYNIYGitGtGVItnvt~~~~~~~qgL~yS~sG~L~~FK 627 (1275)
5089 T 6VSJ_C 548 CLVNDRCQIFANILLNGINSGTTCSTDLQLPNTEVVTGICVKYDLYGITGQGVFKEVKADYYNSWQTLLYDVNGNLNGFR 627 (1275)
5090 T ss_dssp CEETTEEEEEEEEEEESTTCCSBBCSSSCCCCCCCCCSSCEEEEETTEEEEEEEECCCCCCCCSSCCCEECTTSCEEEEE
5091 T ss_pred cccCCceeeeeeeeccCCCCCCCCCCcCCCCCceEEeCeEEEEEeCCCeeEEEEEecCCcccccCccEEEeCCCCEEEEE
5092 Confidence 999999999998 8999998 34689999999999999999999999944 444466778888889999999
5093
5094
5095 Q sp|P0DTC2|SPIK 578 DPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN 657 (1273)
5096 Q Consensus 578 dpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn 657 (1273)
5097 ++.++++..|+||..+.++++..|. +...|+++..++|+++....+....+| .+.|+|-.||+++++|.+
5098 T Consensus 628 n~ttg~~YsV~PC~~v~qQvVV~~~--sivgalls~n~~cs~~~~n~~~~~~~~--------~~~~~t~~gCv~~a~~~t 697 (1275)
5099 T 6VSJ_C 628 DLTTNKTYTIRSCYSGRVSAAFHKD--APEPALLYRNINCSYVFSNNISREENP--------LNYFDSYLGCVVNADNRT 697 (1275)
5100 T ss_dssp CTTTCCEEEEECCCCCEEECCCCTT--CSSCCEEETTCCHHHHHHTTCCSSCCC--------SCCEECSSSEECSCSEEE
5101 T ss_pred cCCCCCEEEEEeCceeceeEEEeCC--CceeEEEEeccceeceeeccceeeeCC--------CcceeccccceeccccCC
5102 Confidence 9999999999999999999999876 567789999999999886444333333 344999999999999887
5103
5104
5105 Q sp|P0DTC2|SPIK 658 N--SYECDIPIGAGICASYQTQTNSPRRARSVASQ-SIIA---YT-MSLGAENSVAYSNNSIAIPTNFTISVTTEILPVS 730 (1273)
5106 Q Consensus 658 n--syecdipigagicasyqtqtnsprrarsvasq-siia---yt-mslgaensvaysnnsiaiptnftisvtteilpvs 730 (1273)
5107 + ..+|++|.|.|||+.+..-.-.+ |++..+ .+.. +. +..........+...|.||+||||+|++|-++++
5108 T Consensus 698 ~~~~~~c~~~~g~giC~dg~~~~~~~---~~~~~~~~~~~~~~~~~~~~~~s~~~~~~~~~i~IP~nFtlsv~~EyiQt~ 774 (1275)
5109 T 6VSJ_C 698 DEALPNCDLRMGAGLCVDYSKSRRAH---RSVSTGYRLTTFEPYTPMLVNDSVQSVDGLYEMQIPTNFTIGHHEEFIQTR 774 (1275)
5110 T ss_dssp EEEESSCSEEETTTEEEEECTTTCSS---SSSTTSEEEEEECSCCCCBCCCSCSSSCCBCSCCBCCCCEEECCEEECCCC
5111 T ss_pred CCcCCCCCCccceEEccCcccceecc---cccCCCceeecccCCcccccCCCCCccCcceEEEccCceEEEEEEEEeecC
5112 Confidence 5 68999999999999998833222 221111 1111 11 1111125566777899999999999999999999
5113
5114
5115 Q sp|P0DTC2|SPIK 731 MTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTP-P----I-KDFGGFNFSQ 804 (1273)
5116 Q Consensus 731 mtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktp-p----i-kdfggfnfsq 804 (1273)
5117 |.|.+|||.+|+||++.+|.+||.|||+||..+|+||.|.+..+|....++++.+++.++.+ + | ...|+|||+.
5118 T Consensus 775 ~~kVsIDCa~YVC~g~~rC~~LL~QYgsfC~~I~~aL~~~~~~~d~~~~~~~~~~~~~~~~s~~~~~~~~~~~~~fN~s~ 854 (1275)
5119 T 6VSJ_C 775 SPKVTIDCAAFVCGDNTACRQQLVEYGSFCVNVNAILNEVNNLLDNMQLQVASALMQGVTISSRLPDGISGPIDDINFSP 854 (1275)
5120 T ss_dssp CCEEECCHHHHHSCSSHHHHHHHGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCBCC----------------
5121 T ss_pred CCCeEEEhhheecCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccccccCCCCCCCCCCCccchh
5122 Confidence 99999999999999999999999999999999999999999999999999999999998875 2 2 4456799999
5123
5124
5125 Q sp|P0DTC2|SPIK 805 ILPD-----------PSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQY 873 (1273)
5126 Q Consensus 805 ilpd-----------pskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqy 873 (1273)
5127 +||. |+++++||+|||||||||+.+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||+|.|
5128 T Consensus 855 ll~~~~~~~~~~~~~~~~~~~RSaIEDLLF~KV~t~glG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpvvd~~~~amY 934 (1275)
5129 T 6VSJ_C 855 LLGCIGSTCAEDGNGPSAIRGRSAIEDLLFDKVKLSDVGFVEAYNNCTGGQEVRDLLCVQSFNGIKVLPPVLSESQISGY 934 (1275)
5130 T ss_dssp ------CCSSCCSSSTTTTTTTTHHHHHHHHHCSSCTTHHHHHHHHHHTTSSTTSSHHHHHHTTCEEECCSSCHHHHHHH
5131 T ss_pred hcccccCCcccCCCCCCccCcccHHHHHHcceeeecCCchHHHHHhccCCcchHHhhcccccCcEEEeCCCCCHHHHHHH
5132 Confidence 9986 56668999999999999999999999999999999999999999999999999999999999999
5133
5134
5135 Q sp|P0DTC2|SPIK 874 TSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVN 953 (1273)
5136 Q Consensus 874 tsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvn 953 (1273)
5137 |++|++|....|||+ |..||||+||.||+||+|+||+||.||||+|||.||.||+.||+.++++++||.|+|||||
5138 T Consensus 935 TasL~g~m~~gg~Ta----aaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~iq~~f~~~~~Al~kiQ~VVN 1010 (1275)
5139 T 6VSJ_C 935 TTGATAAAMFPPWSA----AAGVPFSLSVQYRINGLGVTMNVLSENQKMIASAFNNALGAIQDGFDATNSALGKIQSVVN 1010 (1275)
5140 T ss_dssp HHHHHHTTSCSSSCS----STTCCHHHHHHHHGGGTSCHHHHTTHHHHHHHHHHHHHHHHHHHHHSSCCHHHHHHHHHHH
5141 T ss_pred HHHHHHHhhcccchh----cccCchHHHHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
5142 Confidence 999999999999997 5568999999999999999999999999999999999999999999999999999999999
5143
5144
5145 Q sp|P0DTC2|SPIK 954 QNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECV 1033 (1273)
5146 Q Consensus 954 qnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecv 1033 (1273)
5147 ++++||++|++||+.|||||||.++||++|||++||++||||||+|||.+|++||+|||+|++|+|||+.||..||.|||
5148 T Consensus 1011 ~q~~aL~~L~~qL~~nFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtQ~L~~~~evr~sr~LA~qKINECV 1090 (1275)
5149 T 6VSJ_C 1011 ANAEALNNLLNQLSNRFGAISASLQEILTRLEAVEAKAQIDRLINGRLTALNAYISKQLSDSTLIKVSAAQAIEKVNECV 1090 (1275)
5150 T ss_dssp HHHHHHHHHHHGGGSCCSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
5151 T ss_pred HHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
5152 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5153
5154
5155 Q sp|P0DTC2|SPIK 1034 LGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEP 1112 (1273)
5156 Q Consensus 1034 lgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyep 1112 (1273)
5157 ..||+|.+|||.|.|++|+||.||+|++|+|++|+|.+.++.+++|.+|+++ ++..|+.|+|+.+...|++|.|++|||
5158 T Consensus 1091 KSQS~R~gFCGnGtHi~Si~q~APnGi~FlH~~y~Pt~~~~V~a~~GlC~~~~~~~~p~~g~fv~~n~~~~iT~r~~Y~P 1170 (1275)
5159 T 6VSJ_C 1091 KSQTTRINFCGNGNHILSLVQNAPYGLYFIHFSYVPISFTTANVSPGLCISGDRGLAPKAGYFVQDDGEWKFTGSSYYYP 1170 (1275)
5160 T ss_dssp CSCCSSSSCSSSSCCCCCCEECCTTSCEEECCEEECCSCCCCBCCTTCCSCCCSSSCCCCSCCCBCSSSSBCCCSSBCCC
5161 T ss_pred hcCCCcccccCCCeEEEEeeeccCCeEEEEEEEecccceEEEEEEeeeEecCCceEEecCeEEEecCCEEEEeccCcccC
5162 Confidence 9999999999999999999999999999999999999999999999999994 899999999999988999999999999
5163
5164
5165 Q sp|P0DTC2|SPIK 1113 QIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLG-DISGINASVVN----IQKEIDRLN 1187 (1273)
5166 Q Consensus 1113 qiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlg-disginasvvn----iqkeidrln 1187 (1273)
5167 ..||.+|...-..|||...-+|+++..|..|++..|+|||+|+|||+++...|++ |++.+|+++++ ++.++++|+
5168 T Consensus 1171 r~it~~d~v~~~sC~v~y~n~~~~~l~~~~p~~~df~~el~~~~~n~~~~~p~~~~~~~~~N~t~L~Ei~~l~~~~~~l~ 1250 (1275)
5169 T 6VSJ_C 1171 EPITDKNSVIMSSCAVNYTKAPEVFLNTSIPNPPDFKEELDKWFKNQTSIAPDLSLDFEKLNVTLIKRMKQIEDKIEEIE 1250 (1275)
5170 T ss_dssp CSSCCC--------------------------------------------------------------------------
5171 T ss_pred CCCCccceEEeeccccEEEEcccccCCCCCCCCCChHHHHHHHHhcCCCCCCCcCCCHHHccHHHHHHHHHHHHHHHHHH
5172 Confidence 9999999999999999999999999999999999999999999999999666664 38899999986 666666666
5173
5174
5175 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELG 1204 (1273)
5176 Q Consensus 1188 evaknlneslidlqelg 1204 (1273)
5177 ++.++||.++.++..+.
5178 T Consensus 1251 ~~i~~in~~~~~~~~~~ 1267 (1275)
5179 T 6VSJ_C 1251 SKQKKIENEIARIKKIK 1267 (1275)
5180 T ss_dssp -----------------
5181 T ss_pred HHHHHHHHHHHHHHHhc
5182 Confidence 66777777766665543
5183
5184
5185 No 8
5186 >6OHW_A Spike surface glycoprotein; Coronavirus spike glycoprotein, sialic acid; HET: MAN, NAG, BMA; 2.9A {Human coronavirus OC43}
5187 Probab=100.00 E-value=7.3e-190 Score=1602.12 Aligned_cols=1144 Identities=29% Similarity=0.505 Sum_probs=895.1 Template_Neff=3.700
5188
5189 Q sp|P0DTC2|SPIK 2 FVFLVLLP-----LVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI 68 (1273)
5190 Q Consensus 2 fvflvllp-----lvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai 68 (1273)
5191 |+|+.|+| +....|.. ....-+. |.++ -+-.+|+||||..++++..+-.|++|.+.-++.+-.-
5192 T Consensus 13 ~~~~~~~~~~~~~i~~~~C~~-~~~~~~~~~~~~~~~~~id~s~~~G~yYp~~rvysN~tll~~glfp~~gs~~~~y~-- 89 (1322)
5193 T 6OHW_A 13 YLLGMLVASVLAVIGDLKCTS-DNINDKDTGPPPISTDTVDVTNGLGTYYVLDRVYLNTTLFLNGYYPTSGSTYRNMA-- 89 (1322)
5194 T ss_dssp ------------CCSSBCCCC-TTEECCCCCSCCEEEEECCCTTSTTCBCCTEEECCSEEEEEEEEEECTTCEEEECC--
5195 T ss_pred HHHHHHHHHHHHHhcCccccc-cCCCCCCCCCCCCCcceeecccCceeEEecCeEEeeeeeEecceecCCCCceEEee--
5196 Confidence 56666655 33445765 2222222 3333 3456899999999999999999999999877665321
5197
5198
5199 Q sp|P0DTC2|SPIK 69 HVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNIIRGW---------IFGTTLDSKTQSLLIVNNATN----------- 125 (1273)
5200 Q Consensus 69 hvsgtng---tkrfdnpvlpfndgvyfasteksniirgw---------ifgttldsktqsllivnnatn----------- 125 (1273)
5201 .+|++- --.++++..||+||++....+..|. +|| +||+|.+...++++|.++-.+
5202 T Consensus 90 -~~~t~~~s~~~~y~~~~~~F~dGifvkv~~~~~~-t~~~~~~~yp~~~fGstf~N~s~tvVI~P~~~~~~~~~~~~~~~ 167 (1322)
5203 T 6OHW_A 90 -LKGSVLLSRLWFKPPFLSDFINGIFAKVKNTKVI-KDRVMYSEFPAITIGSTFVNTSYSVVVQPRTINSTQDGDNKLQG 167 (1322)
5204 T ss_dssp -CEESSCEEGGGGSTTTEEECSSEEEEEEECEEEE-ETTEEEEECCCEEEESSCSTTSCEEEEEEEEEC-------CCEE
5205 T ss_pred -eecccccccccccCCccccccCcEEEEEEeeccc-CCCceeeccCceEEeccccCCeeEEEEccCCCCcCccccccccc
5206 Confidence 223322 2456777889999997766655544 444 699999999999999987664
5207
5208
5209 Q sp|P0DTC2|SPIK 126 -VVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIY 204 (1273)
5210 Q Consensus 126 -vvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiy 204 (1273)
5211 ..|.+|.|..|..|...+++.-+| +. -+++. ....+|+|.|. +.|-.|... ..|- |.|++.||.|-+|
5212 T Consensus 168 ~~~it~C~~~vC~~p~~~~~~~~gn-~~--~~~~~-~d~~~~~~~~~-~nfT~d~~~--~~~~----f~F~q~~G~fy~Y 236 (1322)
5213 T 6OHW_A 168 LLEVSVCQYNMCEYPQTICHPNLGN-HR--KELWH-LDTGVVSCLYK-RNFTYDVNA--DYLY----FHFYQEGGTFYAY 236 (1322)
5214 T ss_dssp EEEEEEECCCEEEEEEEECCTTTCC-SS--CCEEE-CCSSCCCEEEE-EEEEECTTC--SEEE----EEEEEETTEEEEE
5215 T ss_pred ceEEeeeeeEecCCCeeEEecCCCC-Cc--eeeeE-eecCCceEEEe-eeecccccc--ceee----EEEEEeCCeEEEE
5216 Confidence 347899999999999988875444 22 23444 66788998765 455444322 1111 9999999999887
5217
5218
5219 Q sp|P0DTC2|SPIK 205 SKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGT 284 (1273)
5220 Q Consensus 205 skhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengt 284 (1273)
5221 ..+...+. .| +...+.|...+++- .+-|+..++ ..++|||++|.+|+|||+|++||.
5222 T Consensus 237 y~d~~~~~------~f-----~f~~~~~~~~~~yy---v~p~~~~~~---------~~~~~~v~~L~~~~~Ll~fd~~G~ 293 (1322)
5223 T 6OHW_A 237 FTDTGVVT------KF-----LFNVYLGMALSHYY---VMPLTCNSK---------LTLEYWVTPLTSRQYLLAFNQDGI 293 (1322)
5224 T ss_dssp EESSSSSB------EE-----EEEEECSSCCCEEE---ECCEECSSC---------CCCCEEEEEEEEEEEEEEECTTSC
5225 T ss_pred EecCCCCc------ce-----eccccceeccceeE---eceeecCCc---------cceeEEEEeceeeeEEEEecCCCe
5226 Confidence 44432221 00 01111122222222 222333332 668999999999999999999999
5227
5228
5229 Q sp|P0DTC2|SPIK 285 ITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVAD 364 (1273)
5230 Q Consensus 285 itdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvad 364 (1273)
5231 ||+||||+-|+++|-||..+||.+++|+|++|+||+||...++|.+.....|+|.++++|.++.++|.|.|+.++||..|
5232 T Consensus 294 It~AvDC~~~~~sEl~C~t~sf~~~tGVY~lS~y~aqp~~~V~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~f~nCnfn 373 (1322)
5233 T 6OHW_A 294 IFNAVDCMSDFMSEIKCKTQSIAPPTGVYELNGYTVQPIADVYRRKPNLPNCNIEAWLNDKSVPSPLNWERKTFSNCNFN 373 (1322)
5234 T ss_dssp EEEEEETTSSHHHHHHHHTTCSSCCSEEEEEEEEECCCSEEEEECCSSCCBCCHHHHHTCSEEECSTTCEEEEEESCBBC
5235 T ss_pred EeEEEecccCcchhheeeecccCCCCceeecCCeEEEeeeEEEEeCCCCCCCCHHHHhcCCCCCCccceEEeEEecCCCC
5236 Confidence 99999999999999999999999999999999999999999999999988999999999999999999999999999999
5237
5238
5239 Q sp|P0DTC2|SPIK 365 YSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK 444 (1273)
5240 Q Consensus 365 ysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk 444 (1273)
5241 +++|++...+++|+||||+|.||.+.||..|++|.|.|..+..++++||.+|.|++||||+|++|+||+++|+-.+.+..
5242 T Consensus 374 ~s~ll~~~~~~~f~C~~ispskl~~~C~ssvtiD~F~ip~~~~~~l~~g~~g~~~~~NYkl~~~~~~C~l~y~~~~~nvn 453 (1322)
5243 T 6OHW_A 374 MSSLMSFIQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS 453 (1322)
5244 T ss_dssp HHHHHHHCEEEEEEEESSCGGGGGGCEEEEEEEEEEECCTTCGGGGSTTCCCHCCCCCCCCCSSSCEEEEEEEEEGGGCE
5245 T ss_pred HHHHhhhceeceeeecCCCHHHHcccccceeEEEEEeccCCcceeecCCCCcHHHhcCccCCCCCCceEEEEEccccccc
5246 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999995554333
5247
5248
5249 Q sp|P0DTC2|SPIK 445 V----GGNYNYLYRLFRKSNLKPFERDI---STEIYQ-----AGSTPCN----------G-------------------- 482 (1273)
5250 Q Consensus 445 v----ggnynylyrlfrksnlkpferdi---steiyq-----agstpcn----------g-------------------- 482 (1273)
5251 + -++||.-|+.-..+.++|.++.. ...+|. .+.+-|+ +
5252 T Consensus 454 ~t~~Nps~wn~ry~f~~~~~~~~~~~~~~~~hdvvYs~~cf~~~~~yCPC~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~ 533 (1322)
5253 T 6OHW_A 454 VSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNFCPCKLNGSCVGSGPGKNNGIGTCPAGTNYLTCD 533 (1322)
5254 T ss_dssp EECCCCCHHHHHTTCCHHHHSCBTTTSSBCTTEEEEESCCEECCTTCCCCBCC-----------CCBBCCCTTCCCBCC-
5255 T ss_pred cccCCccchhhccCcccccccCCCCCCcCCCcceeeeeeeecCCCCcCCCcCCCcccCCCCCCCCCCCcCCCCccccccc
5256 Confidence 2 34677777766667777765411 112222 2222121 0
5257
5258
5259 Q sp|P0DTC2|SPIK 483 ----VEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFEL-----------------------------------LHAPAT 523 (1273)
5260 Q Consensus 483 ----vegfncyfplqsygfqptngvgyqpyrvvvlsfel-----------------------------------lhapat 523 (1273)
5261 ..+..|.-+...+--....|+|+++++++|++++. ...+.|
5262 T Consensus 534 ~~~~~~~~~~~~~~~~~q~~~~~gvg~~c~gl~Vi~~k~g~~~C~C~~~af~g~~~~~~~~~~~~~i~~~~~~~~~~s~t 613 (1322)
5263 T 6OHW_A 534 NLCTPDPITFTGTYKCPQTKSLVGIGEHCSGLAVKSDYCGGNSCTCRPQAFLGWSADSCLQGDKCNIFANFILHDVNSGL 613 (1322)
5264 T ss_dssp ---TTCSSSCCCSSCCSSEECCCCTTCCCCCCEECGGGEEBTTTEECGGGEESEEEEECEETTEEEEEEEEEEEEETSSS
5265 T ss_pred cCCCCCCCccccccCCCCceeeeecccccceEEEEecccCCCCccCCCccccCCCcccccCCCccccccceeecCCCCCC
5266 Confidence 01122211111111123569999999999999988 667889
5267
5268
5269 Q sp|P0DTC2|SPIK 524 VCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVIT 599 (1273)
5270 Q Consensus 524 vcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvit 599 (1273)
5271 ||++ +.+++++.++||++|..|.||+||+++++ ..++.++.+..|-+.-..+++++.++++..|+||..|.++++.
5272 T Consensus 614 vC~~d~~~~~snI~Ln~CVdYNIYGitGqGVItn~n~~~~~~~~GL~ydssgdL~gfKn~ttg~~YsV~PC~~g~VVGi~ 693 (1322)
5273 T 6OHW_A 614 TCSTDLQKANTDIILGVCVNYDLYGILGQGIFVEVNATYYNSWQNLLYDSNGNLYGFRDYITNRTFMIRSCYSGRVSAAF 693 (1322)
5274 T ss_dssp EEBCSSCCCCCCCCBSSEEEEEETTEEEEEEEEEECCCCCCTTEEEEECTTSCEEEEECTTTCCEEEEECCCEEEEEEEE
5275 T ss_pred cCCCcccccCceEEeCeeeeEEeCCccceEEEEecCCCceeccCcEEEcCCCCEEEEEcCCCCcEEEEEeCccCcEEEEE
5276 Confidence 9998 56799999999999999999999999964 5566778888888888889999999999999999999999998
5277
5278
5279 Q sp|P0DTC2|SPIK 600 PGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN--NSYECDIPIGAGICASYQTQ 677 (1273)
5280 Q Consensus 600 pgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn--nsyecdipigagicasyqtq 677 (1273)
5281 ... ++..+.+|.++.|.+|....|..+++| .+-|+|-.||++++.+.. ...+|++|.|.|+|+.|.+
5282 T Consensus 694 tS~--n~t~a~lF~n~~C~~v~~~~~~~~~~~--------~~~f~t~~Gcv~~a~~~t~~~v~~c~~~~g~~~C~~~~~- 762 (1322)
5283 T 6OHW_A 694 HAN--SSEPALLFRNIKCNYVFNNSLTRQLQP--------INYFDSYLGCVVNAYNSTAISVQTCDLTVGSGYCVDYSK- 762 (1322)
5284 T ss_dssp CTT--CSSCEEEEETCCHHHHHHTTTTTTCCC--------SCEEECSSEEEESSEEEEEEEESCCSEEEETTEEEEEC--
5285 T ss_pred eCC--CCCccceeccceeceeeecccceeecc--------ccceeccccceecceecCCceeccccccccCceeeecCC-
5286 Confidence 765 445789999999999998766655555 233999999999999986 4889999999999999988
5287
5288
5289 Q sp|P0DTC2|SPIK 678 TNSPRRARSVAS--QSIIAYTMSL-----GAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECS 750 (1273)
5290 Q Consensus 678 tnsprrarsvas--qsiiaytmsl-----gaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecs 750 (1273)
5291 |+++++... ..+..| +.+ ........+...|.||+||||+|++|-++++|.|.+|||.+|+||++.+|.
5292 T Consensus 763 ---~~gs~~~~~~~~~l~~~-~p~~~~~v~~~~~~~~~~~~IsIP~NFTlsvt~EyIQt~~~kVsIDCa~YVC~~~~~C~ 838 (1322)
5293 T 6OHW_A 763 ---NGGSGGAITTGYRFTNF-EPFTVNSVNDSLEPVGGLYEIQIPSEFTIGNMVEFIQTSSPKVTIDCAAFVCGDYAACK 838 (1322)
5294 T ss_dssp -----------CCSEEEEEE-CCCCCEEECCCSSCBTTBEEEEEEEEEEEEEEEEEEECCCCEEEECHHHHHSCSCHHHH
5295 T ss_pred ---CCCCCceeccCceeeec-cceeecccccCCCCCcceEEEEecCceeeEEEEEEeeecCCCeEEehhheecCCCHHHH
5296 Confidence 444433222 222233 222 111223455568999999999999999999999999999999999999999
5297
5298
5299 Q sp|P0DTC2|SPIK 751 NLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKT----PPIKDF--GGFNFSQILPDPS----KPSKRSFIED 820 (1273)
5300 Q Consensus 751 nlllqygsfctqlnraltgiaveqdkntqevfaqvkqiykt----ppikdf--ggfnfsqilpdps----kpskrsfied 820 (1273)
5301 +||.|||+||..+|+||.+++..+|....+++..+++-++. +.+..| |+||||.+||.+. .+++||+|||
5302 T Consensus 839 ~LL~QYgs~C~~I~~aL~~v~~~~d~~~~~~~~~~~~~~~~s~~l~~~~~~~~g~fN~s~ll~~~~s~~~~~~~RSaIED 918 (1322)
5303 T 6OHW_A 839 SQLVEYGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDDINFSPVLGCLGSECSKASSRSAIED 918 (1322)
5304 T ss_dssp HHGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTCEEEGGGGTCCCCEETTEECTTTCCCCCC----CCSSCHHHH
5305 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhcCccccccccccccCCCCCccccccccCCCCCCCcCccccHHHH
5306 Confidence 99999999999999999999999999999999999998876 444445 6899999999875 3578999999
5307
5308
5309 Q sp|P0DTC2|SPIK 821 LLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAM 900 (1273)
5310 Q Consensus 821 llfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam 900 (1273)
5311 |||+||..+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||++.||++|++|....|||+ |..||||+
5312 T Consensus 919 LLFnKV~tsglG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpVvd~~~~amYTaSL~g~m~~gg~Ta----aaaIPFa~ 994 (1322)
5313 T 6OHW_A 919 LLFDKVKLSDVGFVEAYNNCTGGAEIRDLICVQSYKGIKVLPPLLSENQFSGYTLAATSASLFPPWTA----AAGVPFYL 994 (1322)
5314 T ss_dssp HHHHTCSCSHHHHHHHHTTTTTTSCTTCHHHHHHHTTEEEECCSSCHHHHHHHHHHHHHTTTSSSCGG----GTTCCHHH
5315 T ss_pred HHcceeeeCCcchHHHhHhccCCccHHHhhccceeCcEEEeCCCCCHHHHHHHHHHHHHHhhccCchh----cccCcchH
5316 Confidence 99999999999999999999999999999999999999999999999999999999999999999997 55689999
5317
5318
5319 Q sp|P0DTC2|SPIK 901 QMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 980 (1273)
5320 Q Consensus 901 qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndi 980 (1273)
5321 ||.||+||+|+||+||.||||+|||.||.||+.||+.++.|++||.|+|||||++++||++|++||+.|||||||.++||
5322 T Consensus 995 ~vq~RlN~v~lt~~VL~~NQk~iA~sFN~Ai~~iq~~f~tt~~AL~KiQ~VVN~q~~aL~~L~~qL~~nFgAISssI~DI 1074 (1322)
5323 T 6OHW_A 995 NVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEI 1074 (1322)
5324 T ss_dssp HHHHHHHTTTCCHHHHTTCHHHHHHHHHHHHHHHHHTTTSCCHHHHHHHHHHHHHHHHHHHHHGGGGCCTTSSCSCHHHH
5325 T ss_pred HHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHH
5326 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5327
5328
5329 Q sp|P0DTC2|SPIK 981 LSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGV 1060 (1273)
5330 Q Consensus 981 lsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgv 1060 (1273)
5331 ++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||+|+
5332 T Consensus 1075 y~RLD~LEAdaQVDRLItGRL~aLNafVtQ~L~~~~eVr~sr~LA~qKINECVKSQS~R~gFCGnG~Hi~Si~q~AP~Gi 1154 (1322)
5333 T 6OHW_A 1075 LSRLDALEAEAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGL 1154 (1322)
5334 T ss_dssp HHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSCCCSCSSCSTTSSEEEEEEEEETTEE
5335 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEeeeccCCeE
5336 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5337
5338
5339 Q sp|P0DTC2|SPIK 1061 VFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 1139 (1273)
5340 Q Consensus 1061 vflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvyd 1139 (1273)
5341 +|+|.+|+|.+.++.+++|.+|++| ++..|++|+|+.+...|++|.|++|+|..||.+|...-..|||...-+|+++..
5342 T Consensus 1155 ~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~~g~f~~~n~~~~~T~r~~y~Pr~~t~~d~v~~~sC~v~y~n~~~~~l~ 1234 (1322)
5343 T 6OHW_A 1155 YFIHFSYVPTKYVTARVSPGLCIAGDRGIAPKSGYFVNVNNTWMYTGSGYYYPEPITENNVVVMSTCAVNYTKAPYVMLN 1234 (1322)
5344 T ss_dssp EEEEEEEEEEEEEEEEEESCEECTTSCEEEESSEEEEEETTEEEEEETTEEEEEECCGGGEEEESSCCTTSEECTTCCCC
5345 T ss_pred EEEEeEecccceEEEEEeeeEEecCCeeEEecceEEEeeCCEEEEeccCcccCCCCCccceEEeccceeEEEEcCcccCC
5346 Confidence 9999999999999999999999995 899999999999988999999999999999999999999999999999999999
5347
5348
5349 Q sp|P0DTC2|SPIK 1140 PLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNI-QKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
5350 Q Consensus 1140 plqpeldsfkeeldkyfknhtspdvdlgdisginasvvni-qkeidrlnevaknlneslidlqelg 1204 (1273)
5351 |..|++..|+|||+|+|||+++...|+.. .-+|++++|+ ++||++|++++|+|+..-.+||.+-
5352 T Consensus 1235 ~~~p~~~df~~el~~~~~n~~~~~p~~~~-~~~N~t~Lnlt~~Ei~~L~~~~~~L~~~~~el~~~I 1299 (1322)
5353 T 6OHW_A 1235 TSIPNLPDFKEELDQWFKNQTSVAPDLSL-DYINVTFLDLLIKRMKQIEDKIEEIESKQKKIENEI 1299 (1322)
5354 T ss_dssp ------------------------------------------------------------------
5355 T ss_pred CCCCCCCChHHHHHHHHhcCCCCCCCCCc-cccccceecccHHHHHHHHHHHHHHHHHHHHHHHHH
5356 Confidence 99999999999999999999985555543 2299999999 6999999999999999888887654
5357
5358
5359 No 9
5360 >6NZK_A Spike surface glycoprotein; Coronavirus spike glycoprotein, sialic acid; HET: MJJ, MAN, NAG, BMA; 2.8A {Human coronavirus OC43}
5361 Probab=100.00 E-value=7.3e-190 Score=1602.12 Aligned_cols=1144 Identities=29% Similarity=0.505 Sum_probs=895.1 Template_Neff=3.700
5362
5363 Q sp|P0DTC2|SPIK 2 FVFLVLLP-----LVSSQCVNLTTRTQLP---PAYT-----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAI 68 (1273)
5364 Q Consensus 2 fvflvllp-----lvssqcvnlttrtqlp---payt-----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhai 68 (1273)
5365 |+|+.|+| +....|.. ....-+. |.++ -+-.+|+||||..++++..+-.|++|.+.-++.+-.-
5366 T Consensus 13 ~~~~~~~~~~~~~i~~~~C~~-~~~~~~~~~~~~~~~~~id~s~~~G~yYp~~rvysN~tll~~glfp~~gs~~~~y~-- 89 (1322)
5367 T 6NZK_A 13 YLLGMLVASVLAVIGDLKCTS-DNINDKDTGPPPISTDTVDVTNGLGTYYVLDRVYLNTTLFLNGYYPTSGSTYRNMA-- 89 (1322)
5368 T ss_dssp ------------CCSSBCCCC-TTEECCCCCSCCBCSSCCCCTTSTTCBCCTEEECCSEEEEEEEEECCTTCCCEECC--
5369 T ss_pred HHHHHHHHHHHHHhcCccccc-cCCCCCCCCCCCCCcceeecccCceeEEecCeEEeeeeeEecceecCCCCceEEee--
5370 Confidence 56666655 33445765 2222222 3333 3456899999999999999999999999877665321
5371
5372
5373 Q sp|P0DTC2|SPIK 69 HVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNIIRGW---------IFGTTLDSKTQSLLIVNNATN----------- 125 (1273)
5374 Q Consensus 69 hvsgtng---tkrfdnpvlpfndgvyfasteksniirgw---------ifgttldsktqsllivnnatn----------- 125 (1273)
5375 .+|++- --.++++..||+||++....+..|. +|| +||+|.+...++++|.++-.+
5376 T Consensus 90 -~~~t~~~s~~~~y~~~~~~F~dGifvkv~~~~~~-t~~~~~~~yp~~~fGstf~N~s~tvVI~P~~~~~~~~~~~~~~~ 167 (1322)
5377 T 6NZK_A 90 -LKGSVLLSRLWFKPPFLSDFINGIFAKVKNTKVI-KDRVMYSEFPAITIGSTFVNTSYSVVVQPRTINSTQDGDNKLQG 167 (1322)
5378 T ss_dssp -CEESSCEEGGGGSTTTEEECSSEEEEEEECEEEE-ETTEEEEECCCEEEESSCSTTSCEEEEEEEEEC-------CCEE
5379 T ss_pred -eecccccccccccCCccccccCcEEEEEEeeccc-CCCceeeccCceEEeccccCCeeEEEEccCCCCcCccccccccc
5380 Confidence 223322 2456777889999997766655544 444 699999999999999987664
5381
5382
5383 Q sp|P0DTC2|SPIK 126 -VVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIY 204 (1273)
5384 Q Consensus 126 -vvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknlrefvfknidgyfkiy 204 (1273)
5385 ..|.+|.|..|..|...+++.-+| +. -+++. ....+|+|.|. +.|-.|... ..|- |.|++.||.|-+|
5386 T Consensus 168 ~~~it~C~~~vC~~p~~~~~~~~gn-~~--~~~~~-~d~~~~~~~~~-~nfT~d~~~--~~~~----f~F~q~~G~fy~Y 236 (1322)
5387 T 6NZK_A 168 LLEVSVCQYNMCEYPQTICHPNLGN-HR--KELWH-LDTGVVSCLYK-RNFTYDVNA--DYLY----FHFYQEGGTFYAY 236 (1322)
5388 T ss_dssp EEEEEEECCCEEEEEEEECCTTTCC-SS--CCEEE-CCSSCCCEEEE-EEEEECTTC--SEEE----EEEEEETTEEEEE
5389 T ss_pred ceEEeeeeeEecCCCeeEEecCCCC-Cc--eeeeE-eecCCceEEEe-eeecccccc--ceee----EEEEEeCCeEEEE
5390 Confidence 347899999999999988875444 22 23444 66788998765 455444322 1111 9999999999887
5391
5392
5393 Q sp|P0DTC2|SPIK 205 SKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGT 284 (1273)
5394 Q Consensus 205 skhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgylqprtfllkynengt 284 (1273)
5395 ..+...+. .| +...+.|...+++- .+-|+..++ ..++|||++|.+|+|||+|++||.
5396 T Consensus 237 y~d~~~~~------~f-----~f~~~~~~~~~~yy---v~p~~~~~~---------~~~~~~v~~L~~~~~Ll~fd~~G~ 293 (1322)
5397 T 6NZK_A 237 FTDTGVVT------KF-----LFNVYLGMALSHYY---VMPLTCNSK---------LTLEYWVTPLTSRQYLLAFNQDGI 293 (1322)
5398 T ss_dssp EESSSSSB------EE-----EEEEECSSCCCEEE---ECCEECSSC---------CCCCEEEEECEEEEEEEEECTTSC
5399 T ss_pred EecCCCCc------ce-----eccccceeccceeE---eceeecCCc---------cceeEEEEeceeeeEEEEecCCCe
5400 Confidence 44432221 00 01111122222222 222333332 668999999999999999999999
5401
5402
5403 Q sp|P0DTC2|SPIK 285 ITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVAD 364 (1273)
5404 Q Consensus 285 itdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvad 364 (1273)
5405 ||+||||+-|+++|-||..+||.+++|+|++|+||+||...++|.+.....|+|.++++|.++.++|.|.|+.++||..|
5406 T Consensus 294 It~AvDC~~~~~sEl~C~t~sf~~~tGVY~lS~y~aqp~~~V~~~~~~~~~C~~~~~~~~~~~P~p~~w~R~~f~nCnfn 373 (1322)
5407 T 6NZK_A 294 IFNAVDCMSDFMSEIKCKTQSIAPPTGVYELNGYTVQPIADVYRRKPNLPNCNIEAWLNDKSVPSPLNWERKTFSNCNFN 373 (1322)
5408 T ss_dssp EEEEEETTSSHHHHHHHHTTCSSCCSEEEECCCEECCCSEEEEECCSSCCBCCHHHHHTCSEEECSTTCEEEEEESCEEC
5409 T ss_pred EeEEEecccCcchhheeeecccCCCCceeecCCeEEEeeeEEEEeCCCCCCCCHHHHhcCCCCCCccceEEeEEecCCCC
5410 Confidence 99999999999999999999999999999999999999999999999988999999999999999999999999999999
5411
5412
5413 Q sp|P0DTC2|SPIK 365 YSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSK 444 (1273)
5414 Q Consensus 365 ysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldsk 444 (1273)
5415 +++|++...+++|+||||+|.||.+.||..|++|.|.|..+..++++||.+|.|++||||+|++|+||+++|+-.+.+..
5416 T Consensus 374 ~s~ll~~~~~~~f~C~~ispskl~~~C~ssvtiD~F~ip~~~~~~l~~g~~g~~~~~NYkl~~~~~~C~l~y~~~~~nvn 453 (1322)
5417 T 6NZK_A 374 MSSLMSFIQADSFTCNNIDAAKIYGMCFSSITIDKFAIPNGRKVDLQLGNLGYLQSFNYRIDTTATSCQLYYNLPAANVS 453 (1322)
5418 T ss_dssp HHHHHHHCEEEEEEEESSCGGGGGGCEEEEEEEEEEECCTTCGGGGSTTCCCHCCCCCCCCCSSSCEEEEEEEEEGGGCE
5419 T ss_pred HHHHhhhceeceeeecCCCHHHHcccccceeEEEEEeccCCcceeecCCCCcHHHhcCccCCCCCCceEEEEEccccccc
5420 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999995554333
5421
5422
5423 Q sp|P0DTC2|SPIK 445 V----GGNYNYLYRLFRKSNLKPFERDI---STEIYQ-----AGSTPCN----------G-------------------- 482 (1273)
5424 Q Consensus 445 v----ggnynylyrlfrksnlkpferdi---steiyq-----agstpcn----------g-------------------- 482 (1273)
5425 + -++||.-|+.-..+.++|.++.. ...+|. .+.+-|+ +
5426 T Consensus 454 ~t~~Nps~wn~ry~f~~~~~~~~~~~~~~~~hdvvYs~~cf~~~~~yCPC~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~ 533 (1322)
5427 T 6NZK_A 454 VSRFNPSTWNKRFGFIEDSVFKPRPAGVLTNHDVVYAQHCFKAPKNFCPCKLNGSCVGSGPGKNNGIGTCPAGTNYLTCD 533 (1322)
5428 T ss_dssp EECCCCCHHHHHTTCCHHHHSCBTTTSSBCTTEEEEESSCEECCTTEEEEECC-----------CCBBCCCTTCEEECC-
5429 T ss_pred cccCCccchhhccCcccccccCCCCCCcCCCcceeeeeeeecCCCCcCCCcCCCcccCCCCCCCCCCCcCCCCccccccc
5430 Confidence 2 34677777766667777765411 112222 2222121 0
5431
5432
5433 Q sp|P0DTC2|SPIK 483 ----VEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFEL-----------------------------------LHAPAT 523 (1273)
5434 Q Consensus 483 ----vegfncyfplqsygfqptngvgyqpyrvvvlsfel-----------------------------------lhapat 523 (1273)
5435 ..+..|.-+...+--....|+|+++++++|++++. ...+.|
5436 T Consensus 534 ~~~~~~~~~~~~~~~~~q~~~~~gvg~~c~gl~Vi~~k~g~~~C~C~~~af~g~~~~~~~~~~~~~i~~~~~~~~~~s~t 613 (1322)
5437 T 6NZK_A 534 NLCTPDPITFTGTYKCPQTKSLVGIGEHCSGLAVKSDYCGGNSCTCRPQAFLGWSADSCLQGDKCNIFANFILHDVNSGL 613 (1322)
5438 T ss_dssp ---CSCSSSCCCSSCCSSEECCCCTTCCCCCCEECGGGEEBTTTEECGGGEESEEEEECEETTEEEEEEEEEEEEETSSS
5439 T ss_pred cCCCCCCCccccccCCCCceeeeecccccceEEEEecccCCCCccCCCccccCCCcccccCCCccccccceeecCCCCCC
5440 Confidence 01122211111111123569999999999999988 667889
5441
5442
5443 Q sp|P0DTC2|SPIK 524 VCGP---KKSTNLVKNKCVNFNFNGLTGTGVLTESN-KKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVIT 599 (1273)
5444 Q Consensus 524 vcgp---kkstnlvknkcvnfnfngltgtgvltesn-kkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvit 599 (1273)
5445 ||++ +.+++++.++||++|..|.||+||+++++ ..++.++.+..|-+.-..+++++.++++..|+||..|.++++.
5446 T Consensus 614 vC~~d~~~~~snI~Ln~CVdYNIYGitGqGVItn~n~~~~~~~~GL~ydssgdL~gfKn~ttg~~YsV~PC~~g~VVGi~ 693 (1322)
5447 T 6NZK_A 614 TCSTDLQKANTDIILGVCVNYDLYGILGQGIFVEVNATYYNSWQNLLYDSNGNLYGFRDYITNRTFMIRSCYSGRVSAAF 693 (1322)
5448 T ss_dssp EEECSSCCCCCCCCBSSEEEEEETTEEEEEEEEEECCCCCCTTEEEEECTTSCEEEEECTTTCCEEEEECCCEECCEEEE
5449 T ss_pred cCCCcccccCceEEeCeeeeEEeCCccceEEEEecCCCceeccCcEEEcCCCCEEEEEcCCCCcEEEEEeCccCcEEEEE
5450 Confidence 9998 56799999999999999999999999964 5566778888888888889999999999999999999999998
5451
5452
5453 Q sp|P0DTC2|SPIK 600 PGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVN--NSYECDIPIGAGICASYQTQ 677 (1273)
5454 Q Consensus 600 pgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvn--nsyecdipigagicasyqtq 677 (1273)
5455 ... ++..+.+|.++.|.+|....|..+++| .+-|+|-.||++++.+.. ...+|++|.|.|+|+.|.+
5456 T Consensus 694 tS~--n~t~a~lF~n~~C~~v~~~~~~~~~~~--------~~~f~t~~Gcv~~a~~~t~~~v~~c~~~~g~~~C~~~~~- 762 (1322)
5457 T 6NZK_A 694 HAN--SSEPALLFRNIKCNYVFNNSLTRQLQP--------INYFDSYLGCVVNAYNSTAISVQTCDLTVGSGYCVDYSK- 762 (1322)
5458 T ss_dssp CTT--CSSCEEEEETCCHHHHHHTTTTTTCCC--------SCEEEETTEEEESSEEEEEEEESCCSEEEETTEEEEEC--
5459 T ss_pred eCC--CCCccceeccceeceeeecccceeecc--------ccceeccccceecceecCCceeccccccccCceeeecCC-
5460 Confidence 765 445789999999999998766655555 233999999999999986 4889999999999999988
5461
5462
5463 Q sp|P0DTC2|SPIK 678 TNSPRRARSVAS--QSIIAYTMSL-----GAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECS 750 (1273)
5464 Q Consensus 678 tnsprrarsvas--qsiiaytmsl-----gaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecs 750 (1273)
5465 |+++++... ..+..| +.+ ........+...|.||+||||+|++|-++++|.|.+|||.+|+||++.+|.
5466 T Consensus 763 ---~~gs~~~~~~~~~l~~~-~p~~~~~v~~~~~~~~~~~~IsIP~NFTlsvt~EyIQt~~~kVsIDCa~YVC~~~~~C~ 838 (1322)
5467 T 6NZK_A 763 ---NGGSGGAITTGYRFTNF-EPFTVNSVNDSLEPVGGLYEIQIPSEFTIGNMVEFIQTSSPKVTIDCAAFVCGDYAACK 838 (1322)
5468 T ss_dssp -----------CCSEEEEEE-CCCCCEEECCCSSCBTTBEEEEEEEEEEEEEEEEEEECCCCEEEECHHHHHSCSCHHHH
5469 T ss_pred ---CCCCCceeccCceeeec-cceeecccccCCCCCcceEEEEecCceeeEEEEEEeeecCCCeEEehhheecCCCHHHH
5470 Confidence 444433222 222233 222 111223455568999999999999999999999999999999999999999
5471
5472
5473 Q sp|P0DTC2|SPIK 751 NLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKT----PPIKDF--GGFNFSQILPDPS----KPSKRSFIED 820 (1273)
5474 Q Consensus 751 nlllqygsfctqlnraltgiaveqdkntqevfaqvkqiykt----ppikdf--ggfnfsqilpdps----kpskrsfied 820 (1273)
5475 +||.|||+||..+|+||.+++..+|....+++..+++-++. +.+..| |+||||.+||.+. .+++||+|||
5476 T Consensus 839 ~LL~QYgs~C~~I~~aL~~v~~~~d~~~~~~~~~~~~~~~~s~~l~~~~~~~~g~fN~s~ll~~~~s~~~~~~~RSaIED 918 (1322)
5477 T 6NZK_A 839 SQLVEYGSFCDNINAILTEVNELLDTTQLQVANSLMNGVTLSTKLKDGVNFNVDDINFSPVLGCLGSECSKASSRSAIED 918 (1322)
5478 T ss_dssp HHGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCEEEGGGGTCCCCEETTEECTTTCCCCCC----CCSCCHHHH
5479 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhccHHHHHHHHHHhcCccccccccccccCCCCCccccccccCCCCCCCcCccccHHHH
5480 Confidence 99999999999999999999999999999999999998876 444445 6899999999875 3578999999
5481
5482
5483 Q sp|P0DTC2|SPIK 821 LLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAM 900 (1273)
5484 Q Consensus 821 llfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfam 900 (1273)
5485 |||+||..+|.|+.+.|.+|.+...+|||+|||.|||+.||||++++||++.||++|++|....|||+ |..||||+
5486 T Consensus 919 LLFnKV~tsglG~~~~Yk~Ct~g~~i~DL~CAQyyNGImVLPpVvd~~~~amYTaSL~g~m~~gg~Ta----aaaIPFa~ 994 (1322)
5487 T 6NZK_A 919 LLFDKVKLSDVGFVEAYNNCTGGAEIRDLICVQSYKGIKVLPPLLSENQFSGYTLAATSASLFPPWTA----AAGVPFYL 994 (1322)
5488 T ss_dssp HHHHTCSSSHHHHHHHHHTTTTTCCTTCHHHHHHHTTEEEECCSSCHHHHHHHHHHHHHTTTSSSCGG----GTTCCHHH
5489 T ss_pred HHcceeeeCCcchHHHhHhccCCccHHHhhccceeCcEEEeCCCCCHHHHHHHHHHHHHHhhccCchh----cccCcchH
5490 Confidence 99999999999999999999999999999999999999999999999999999999999999999997 55689999
5491
5492
5493 Q sp|P0DTC2|SPIK 901 QMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 980 (1273)
5494 Q Consensus 901 qmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndi 980 (1273)
5495 ||.||+||+|+||+||.||||+|||.||.||+.||+.++.|++||.|+|||||++++||++|++||+.|||||||.++||
5496 T Consensus 995 ~vq~RlN~v~lt~~VL~~NQk~iA~sFN~Ai~~iq~~f~tt~~AL~KiQ~VVN~q~~aL~~L~~qL~~nFgAISssI~DI 1074 (1322)
5497 T 6NZK_A 995 NVQYRINGLGVTMDVLSQNQKLIANAFNNALYAIQEGFDATNSALVKIQAVVNANAEALNNLLQQLSNRFGAISASLQEI 1074 (1322)
5498 T ss_dssp HHHHHHHTTTCCHHHHTTCHHHHHHHHHHHHHHHHHTTTSCCHHHHHHHHHHHHHHHHHHHHHGGGGCCTTSSCSCHHHH
5499 T ss_pred HHHHHhcccccchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHH
5500 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5501
5502
5503 Q sp|P0DTC2|SPIK 981 LSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGV 1060 (1273)
5504 Q Consensus 981 lsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgv 1060 (1273)
5505 ++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||+|+
5506 T Consensus 1075 y~RLD~LEAdaQVDRLItGRL~aLNafVtQ~L~~~~eVr~sr~LA~qKINECVKSQS~R~gFCGnG~Hi~Si~q~AP~Gi 1154 (1322)
5507 T 6NZK_A 1075 LSRLDALEAEAQIDRLINGRLTALNAYVSQQLSDSTLVKFSAAQAMEKVNECVKSQSSRINFCGNGNHIISLVQNAPYGL 1154 (1322)
5508 T ss_dssp HHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSCCCSCCSSSTTSSEEEEEEEEETTEE
5509 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEeeeccCCeE
5510 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5511
5512
5513 Q sp|P0DTC2|SPIK 1061 VFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYD 1139 (1273)
5514 Q Consensus 1061 vflhvtyvpaqeknfttapaichdg-kahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvyd 1139 (1273)
5515 +|+|.+|+|.+.++.+++|.+|++| ++..|++|+|+.+...|++|.|++|+|..||.+|...-..|||...-+|+++..
5516 T Consensus 1155 ~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~~g~f~~~n~~~~~T~r~~y~Pr~~t~~d~v~~~sC~v~y~n~~~~~l~ 1234 (1322)
5517 T 6NZK_A 1155 YFIHFSYVPTKYVTARVSPGLCIAGDRGIAPKSGYFVNVNNTWMYTGSGYYYPEPITENNVVVMSTCAVNYTKAPYVMLN 1234 (1322)
5518 T ss_dssp EEEEEEEEEEEEEEEEEESCEECTTSCEEEESSEEEEEETTEEEEEESSSCCEEECCGGGEEEESSCCTTSEECTTCCCC
5519 T ss_pred EEEEeEecccceEEEEEeeeEEecCCeeEEecceEEEeeCCEEEEeccCcccCCCCCccceEEeccceeEEEEcCcccCC
5520 Confidence 9999999999999999999999995 899999999999988999999999999999999999999999999999999999
5521
5522
5523 Q sp|P0DTC2|SPIK 1140 PLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNI-QKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
5524 Q Consensus 1140 plqpeldsfkeeldkyfknhtspdvdlgdisginasvvni-qkeidrlnevaknlneslidlqelg 1204 (1273)
5525 |..|++..|+|||+|+|||+++...|+.. .-+|++++|+ ++||++|++++|+|+..-.+||.+-
5526 T Consensus 1235 ~~~p~~~df~~el~~~~~n~~~~~p~~~~-~~~N~t~Lnlt~~Ei~~L~~~~~~L~~~~~el~~~I 1299 (1322)
5527 T 6NZK_A 1235 TSIPNLPDFKEELDQWFKNQTSVAPDLSL-DYINVTFLDLLIKRMKQIEDKIEEIESKQKKIENEI 1299 (1322)
5528 T ss_dssp ------------------------------------------------------------------
5529 T ss_pred CCCCCCCChHHHHHHHHhcCCCCCCCCCc-cccccceecccHHHHHHHHHHHHHHHHHHHHHHHHH
5530 Confidence 99999999999999999999985555543 2299999999 6999999999999999888887654
5531
5532
5533 No 10
5534 >6M15_A Spike glycoprotein; VIRAL PROTEIN; HET: BMA, NAG; 2.38A {Rhinolophus bat coronavirus HKU2}
5535 Probab=100.00 E-value=6.1e-154 Score=1294.04 Aligned_cols=832 Identities=28% Similarity=0.472 Sum_probs=633.8 Template_Neff=3.500
5536
5537 Q sp|P0DTC2|SPIK 273 RTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYA 352 (1273)
5538 Q Consensus 273 rtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvya 352 (1273)
5539 -++||.|+.||+|+|++||+-+|++|-+|..++|....|.|..+++++ |+-..+|.+++ ..|+|..++||.. +++.
5540 T Consensus 216 s~~Ll~fDvNGtItdaIdC~~Sp~~eLaCsy~SFnfsdGVYpfSny~v-pkfiVYR~ssv-~nctFsN~snA~p--Si~~ 291 (1118)
5541 T 6M15_A 216 SSVLVLTDQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSEVEY-PVALYTVVHNM-SVCPQRPESYCGS--NYCP 291 (1118)
5542 T ss_dssp EEEEEEECTTSCEEEEEETTSSHHHHHHHHHTCSSCCSEEEEEEECCC-CEEEESCCSCC-EECCCCCCCCCCS--SCCC
5543 T ss_pred eeeeeeecCCCcEEEEEeccCCcccccceEeccccCCCceeccCCcee-ceEEEEEecCc-ceeecCHHhcCCC--Cccc
5544 Confidence 468999999999999999999999999999999999999999999999 99888998888 8899999999988 9999
5545
5546
5547 Q sp|P0DTC2|SPIK 353 WNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYN-YKLPDDFTG 431 (1273)
5548 Q Consensus 353 wnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadyn-yklpddftg 431 (1273)
5549 |.|+.++||..|+|.|. .+-+..|| |.+|.
5550 T Consensus 292 wqR~tfsNCNFNFSfLs---------------------------------------------Sdfm~SYN~y~~P~---- 322 (1118)
5551 T 6M15_A 292 FKRVVFSNCVVNYTSWT---------------------------------------------SGLLRDYQHLVLPN---- 322 (1118)
5552 T ss_dssp CCEEEECSEECCGGGGS---------------------------------------------CSCHHHHGGGBCTT----
5553 T ss_pred cEEEEeeceeeeccEec---------------------------------------------CcchheeeeccCCC----
5554 Confidence 99999999999999988 12222333 33343
5555
5556
5557 Q sp|P0DTC2|SPIK 432 CVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEI------YQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGY 505 (1273)
5558 Q Consensus 432 cviawnsnnldskvggnynylyrlfrksnlkpferdistei------yqagstpcngvegfncyfplqsygfqptngvgy 505 (1273)
5559 | |- ++.+ .+-..|.++--.+.+-+- .....+-- |+-|...|-|+..-.|- .
5560 T Consensus 323 c----nF-nPet-Ngl~FNsl~g~Ckqsv~~--f~g~~tcCy~~VIS~~~gp~~ckG~~~geCg---------------~ 379 (1118)
5561 T 6M15_A 323 G----KF-NPFT-ECNGLNRIVDDCVTGFVL--RVGRGTAVNRTVITPYLKPNECFGWSWNDYQ---------------D 379 (1118)
5562 T ss_dssp S----CB-CSCS-EEESBCSSCCSEEECEEE--EEEEEECBTTBCCCCCCCTTEEEEEEEEETT---------------T
5563 T ss_pred C----CC-CCcc-CCcCCccccCCCccceEE--EecCceeeEEEEECCCCCCCccceeeecccc---------------c
5564 Confidence 1 10 0111 111111100000000000 00000000 01133334444433221 0
5565
5566
5567 Q sp|P0DTC2|SPIK 506 QPYRVVVLSFEL-L-HAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLE 583 (1273)
5568 Q Consensus 506 qpyrvvvlsfel-l-hapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtle 583 (1273)
5569 -|-..+.| - -.++|+|.. ..++++.++||++|..|.+|+||++++|..+..+|.+..+-.| ..++++ +++
5570 T Consensus 380 ----~Vyv~~~~~g~S~~aTvCPv-d~tnI~Ld~CVdYNIYG~tGqGVItnsn~~~~~~q~GLy~ts~-L~~vk~--tg~ 451 (1118)
5571 T 6M15_A 380 ----SIYDWWIADFVSTGAFVCEK-NPDAPRTGVCITYTIEKVTFQGVLYESNFTFAQYYNVLYFGSQ-LKYVRI--LGK 451 (1118)
5572 T ss_dssp ----TEEEEEEEECCCCSCEEESS-CCCCCCTTSEEEEEETTEEEEEEEEECCCCCCTTCSEEEETTE-EEEEEE--TTE
5573 T ss_pred ----eEEeEeecCCccCCcccCCC-CCCCCccCeeEeEEeCCceeeEEEEEcCccceehhceEEEeee-eEEEEe--CCc
5574 Confidence 22333333 1 356899988 6689999999999999999999999999988888888777444 467777 999
5575
5576
5577 Q sp|P0DTC2|SPIK 584 ILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNN--SYE 661 (1273)
5578 Q Consensus 584 ilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnn--sye 661 (1273)
5579 +..|+||..+.++++..| ++.++.|++.+||.++.+..+.. +.||-.++. -|||-.||++++...++ ..+
5580 T Consensus 452 ~Y~V~PC~~v~qQvVv~~---~~~vglLt~S~ncn~~~~~~~~~---~~r~~~~~~--~fdt~~Gcv~~~~n~~~~~~~~ 523 (1118)
5581 T 6M15_A 452 VYEVAPCFEASYDVLFRS---SSSFGLLYRSFDCNQLRISASRF---AERLLPSHN--GTATALGCLFNATYAPNDTMVN 523 (1118)
5582 T ss_dssp EEEEECCTTSEEEEEEEE---TTEEEEEETTCCCCHHHHTSSTT---TTTCCGGGC--SEEETTEEEESSEEEEEEEESS
5583 T ss_pred EEEEecCcccceeEEEeC---CCeEEEEEcccccceeeeecccc---ccccCCCCC--CcccceeeEEEeecCCCCCCcc
5584 Confidence 999999999999999988 47899999999998887655544 334443333 39999999999987744 699
5585
5586
5587 Q sp|P0DTC2|SPIK 662 CDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMY 741 (1273)
5588 Q Consensus 662 cdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmy 741 (1273)
5589 |+.|+|.|||+.+ .-.-.+||.+-+ .+. ... .+.....+.|.||+||||+|++|-++++|.|.+|||.+|
5590 T Consensus 524 C~~p~g~giC~dg-~~~~~~r~~~l~------~~~-~~~--v~p~~~~~~IsIPtNFTlsvt~EYIQt~~~kVsVDCa~Y 593 (1118)
5591 T 6M15_A 524 CTNPLGDGFCADL-LSNVVVRRMTFE------KHD-TTY--VAPVTNERFTELPLDHQLVLTEQFLQTTMPKFSISCETY 593 (1118)
5592 T ss_dssp CSSEEETTEEEEC-SSSCEEEEECCC------CBC-CSC--CCCCCSSEEEEEEEEEEEEEEEEEEECCCCEEEECHHHH
5593 T ss_pred CCCCceeeEecCC-cceeceeeeeee------ccc-ccc--ccCcccceeEEccCceEeEEEEEEEeccCCCeEEecchh
5594 Confidence 9999999999999 333334432222 221 111 122334477899999999999999999999999999999
5595
5596
5597 Q sp|P0DTC2|SPIK 742 ICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQI-LPDPS----KPSKRS 816 (1273)
5598 Q Consensus 742 icgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqi-lpdps----kpskrs 816 (1273)
5599 +||++.+|.+||.|||+||..+|+||.+.+..+|.+..+++..+|..... +....|+||||++ +|..+ ++++||
5600 T Consensus 594 VCngn~~C~~LL~QYgs~C~~I~~aL~~~a~led~~~~~~~s~~~~~~~~-~~~~~~~FN~S~~~lp~~~~~~~~~~~RS 672 (1118)
5601 T 6M15_A 594 ICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLDSDVSGLYSTIAAKTSS-ITPTTDRFNVSQFFLPKVQSNSERFESRS 672 (1118)
5602 T ss_dssp HSSSCHHHHTTGGGSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHBBCCCS-SCCBCSSCCCTTTTSCCCCCSSSCCCCCC
5603 T ss_pred ccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHHhhhccC-cCCCCCCccccccccCCCCCCCccccccc
5604 Confidence 99999999999999999999999999999999999999999888766433 3366888999998 67654 346899
5605
5606
5607 Q sp|P0DTC2|SPIK 817 FIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGA--GAAL 894 (1273)
5608 Q Consensus 817 fiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfga--gaal 894 (1273)
5609 +||||||+||..+|.|+.+.|.+|.+ -.+|||+|||.+||+.||||++++||++.|| +.++.||+||+ ++|.
5610 T Consensus 673 ~IEDLLF~KV~t~glG~~~~Yk~Ct~-~~i~DL~CaQyyNGimVLP~v~d~~~~amYT-----asl~ggm~~Ggit~sAa 746 (1118)
5611 T 6M15_A 673 VIEDLLFSKIETTGPGFYGDYYNCKK-NAIQDLTCAQYHNGILVIPPVMDAETLGMYG-----GIAAASLTLGIFGGQAG 746 (1118)
5612 T ss_dssp HHHHHHHHSSCCCCSSHHHHHHHHHH-HCCTTCCCCCEETTEEEECCSSCGGGCCTTS-----STTCBCSSTTTTCSSCC
5613 T ss_pred HHHHHhccceEecCCCchHhHHHhhc-chhhHHhcccccCcEEEcCCCCCHHHHHHHH-----HHHHHHHHhhhhcchhc
5614 Confidence 99999999999999999999999999 6799999999999999999999999999999 44566899988 6789
5615
5616
5617 Q sp|P0DTC2|SPIK 895 QIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAIS 974 (1273)
5618 Q Consensus 895 qipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgais 974 (1273)
5619 .|||||||.||+||+|+||+||.||||+|||.||.|++.||+.++.+++||.|+|||||++++||++|++||+.||||||
5620 T Consensus 747 aiPFa~~vq~RlN~valt~~VL~~NQk~iA~sFN~A~~~iq~~f~tt~~AL~KIQ~VVN~q~~aL~~L~~QL~nnFgAIS 826 (1118)
5621 T 6M15_A 747 ITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVGKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS 826 (1118)
5622 T ss_dssp CCBHHHHHHHHHHHTTSCSSCCHHHHHHHHHHHHHHHHTGGGCCTTTCHHHHHHHHHHHHHHHHHHHHHHTTTSCTTSSC
5623 T ss_pred hhhHHHHHHHHHhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHH
5624 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5625
5626
5627 Q sp|P0DTC2|SPIK 975 SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQ 1054 (1273)
5628 Q Consensus 975 svlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpq 1054 (1273)
5629 |.++||++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||
5630 T Consensus 827 SSI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtq~l~~~~ev~~sr~LA~qKINECVKSQS~R~GFCGnGtHi~Si~q 906 (1118)
5631 T 6M15_A 827 TNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSLMQ 906 (1118)
5632 T ss_dssp SCHHHHHHHBCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTTSSSEEEEEEEE
5633 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccCcccCCCCCCeEeEeecc
5634 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5635
5636
5637 Q sp|P0DTC2|SPIK 1055 SAPHGVVFLHVTYVPAQEKNFTTAPAICHD----GKAHFPREGVFVSNG-THWFVTQRNFYEPQIITTDNTFVSGNCDVV 1129 (1273)
5638 Q Consensus 1055 saphgvvflhvtyvpaqeknfttapaichd----gkahfpregvfvsng-thwfvtqrnfyepqiittdntfvsgncdvv 1129 (1273)
5639 .||+|++|+|.+|+|.+-++.+++|.+|++ +++..||+|+|+.+. +.|++|.|++|+|..||.+|.... .||+.
5640 T Consensus 907 ~APnGi~F~H~~y~Pt~~~~V~a~~GlC~~~~~~~~~~~~~~g~f~~~n~~~w~iT~r~my~Pr~it~~d~v~~-sc~v~ 985 (1118)
5641 T 6M15_A 907 NAPSGIMFFHYSLIPNNTITVKTTPGLCESDELGSKCIVAKDGVLVSANLSYWQWSPRNLYKPENLTFANVIAV-SRGAN 985 (1118)
5642 T ss_dssp EETTEEEEEEEEEEEEEEEEEEEESCEESSSSTTCCEEEESSSEEEESSCSSCEEECTTSCCCEECCTTTEEEE-CCCTT
5643 T ss_pred cCCCeEEEEEEEeccCceeEEEEeeeeEccCCCCCcEEEecccEEEEcCCCEEEECccccccCCCCCccCeEEE-ecCce
5644 Confidence 999999999999999999999999999999 457999999999864 999999999999999999998777 78999
5645
5646
5647 Q sp|P0DTC2|SPIK 1130 IGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQY 1209 (1273)
5648 Q Consensus 1130 igivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqy 1209 (1273)
5649 ...+|.++..|..|++-.|+|||+|+|||+++.-.||.+.+ +|++++|++.||++|+|+.|+||+++|||++|++||+|
5650 T Consensus 986 y~~vn~t~~~p~ipd~~Df~eel~e~~kn~s~~~pdl~~~~-~N~T~LNLs~EI~~LqevIk~LN~s~IdLe~L~~~e~Y 1064 (1118)
5651 T 6M15_A 986 YTTLNRTFDIPELNSTFPIDEEFREYFQNMSSELQALKNLT-ADMSKLNISAEIQLINEIAHNVSNMRVEVEKFQRYVNY 1064 (1118)
5652 T ss_dssp CEECSSCCCC----------------------------------------------------------------------
5653 T ss_pred EEEeccccCCCCCcCCCChHHHHHHHHhhcCccccccccce-ecCceechHHHHHHHHHHHHHHHhccccHHHhCeeeEE
5654 Confidence 99999999999999999999999999999988777787766 99999999999999999999999999999999999999
5655
5656
5657 Q sp|P0DTC2|SPIK 1210 IKWPWY 1215 (1273)
5658 Q Consensus 1210 ikwpwy 1215 (1273)
5659 |||.-.
5660 T Consensus 1065 iKW~~~ 1070 (1118)
5661 T 6M15_A 1065 VKLEVL 1070 (1118)
5662 T ss_dssp ------
5663 T ss_pred eeceee
5664 Confidence 999854
5665
5666
5667 No 11
5668 >6M15_B Spike glycoprotein; VIRAL PROTEIN; HET: NAG, BMA; 2.38A {Rhinolophus bat coronavirus HKU2}
5669 Probab=100.00 E-value=6.1e-154 Score=1294.04 Aligned_cols=832 Identities=28% Similarity=0.472 Sum_probs=633.8 Template_Neff=3.500
5670
5671 Q sp|P0DTC2|SPIK 273 RTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYA 352 (1273)
5672 Q Consensus 273 rtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasvya 352 (1273)
5673 -++||.|+.||+|+|++||+-+|++|-+|..++|....|.|..+++++ |+-..+|.+++ ..|+|..++||.. +++.
5674 T Consensus 216 s~~Ll~fDvNGtItdaIdC~~Sp~~eLaCsy~SFnfsdGVYpfSny~v-pkfiVYR~ssv-~nctFsN~snA~p--Si~~ 291 (1118)
5675 T 6M15_B 216 SSVLVLTDQSGAVTRYSYCADGFVNGLQCKLRLFDIPPGVYSNSEVEY-PVALYTVVHNM-SVCPQRPESYCGS--NYCP 291 (1118)
5676 T ss_dssp EEEEEEECTTSCEEEEEETTSSHHHHHHHHHTCSSCCSEEEEEEECCC-CEEEESCCSCC-EECCCCCCCCCCS--SCCC
5677 T ss_pred eeeeeeecCCCcEEEEEeccCCcccccceEeccccCCCceeccCCcee-ceEEEEEecCc-ceeecCHHhcCCC--Cccc
5678 Confidence 468999999999999999999999999999999999999999999999 99888998888 8899999999988 9999
5679
5680
5681 Q sp|P0DTC2|SPIK 353 WNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYN-YKLPDDFTG 431 (1273)
5682 Q Consensus 353 wnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadyn-yklpddftg 431 (1273)
5683 |.|+.++||..|+|.|. .+-+..|| |.+|.
5684 T Consensus 292 wqR~tfsNCNFNFSfLs---------------------------------------------Sdfm~SYN~y~~P~---- 322 (1118)
5685 T 6M15_B 292 FKRVVFSNCVVNYTSWT---------------------------------------------SGLLRDYQHLVLPN---- 322 (1118)
5686 T ss_dssp CCEEEECSEECCGGGGS---------------------------------------------CSCHHHHGGGBCTT----
5687 T ss_pred cEEEEeeceeeeccEec---------------------------------------------CcchheeeeccCCC----
5688 Confidence 99999999999999988 12222333 33343
5689
5690
5691 Q sp|P0DTC2|SPIK 432 CVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEI------YQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGY 505 (1273)
5692 Q Consensus 432 cviawnsnnldskvggnynylyrlfrksnlkpferdistei------yqagstpcngvegfncyfplqsygfqptngvgy 505 (1273)
5693 | |- ++.+ .+-..|.++--.+.+-+- .....+-- |+-|...|-|+..-.|- .
5694 T Consensus 323 c----nF-nPet-Ngl~FNsl~g~Ckqsv~~--f~g~~tcCy~~VIS~~~gp~~ckG~~~geCg---------------~ 379 (1118)
5695 T 6M15_B 323 G----KF-NPFT-ECNGLNRIVDDCVTGFVL--RVGRGTAVNRTVITPYLKPNECFGWSWNDYQ---------------D 379 (1118)
5696 T ss_dssp S----CB-CSCS-EEESBCSSCCSEEECEEE--EEEEEECBTTBCCCCCCCTTEEEEEEEEETT---------------T
5697 T ss_pred C----CC-CCcc-CCcCCccccCCCccceEE--EecCceeeEEEEECCCCCCCccceeeecccc---------------c
5698 Confidence 1 10 0111 111111100000000000 00000000 01133334444433221 0
5699
5700
5701 Q sp|P0DTC2|SPIK 506 QPYRVVVLSFEL-L-HAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLE 583 (1273)
5702 Q Consensus 506 qpyrvvvlsfel-l-hapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtle 583 (1273)
5703 -|-..+.| - -.++|+|.. ..++++.++||++|..|.+|+||++++|..+..+|.+..+-.| ..++++ +++
5704 T Consensus 380 ----~Vyv~~~~~g~S~~aTvCPv-d~tnI~Ld~CVdYNIYG~tGqGVItnsn~~~~~~q~GLy~ts~-L~~vk~--tg~ 451 (1118)
5705 T 6M15_B 380 ----SIYDWWIADFVSTGAFVCEK-NPDAPRTGVCITYTIEKVTFQGVLYESNFTFAQYYNVLYFGSQ-LKYVRI--LGK 451 (1118)
5706 T ss_dssp ----TEEEEEEEECCCCSCEEESS-CCCCCCTTSEEEEEETTEEEEEEEEECCCCCCTTCSEEEETTE-EEEEEE--TTE
5707 T ss_pred ----eEEeEeecCCccCCcccCCC-CCCCCccCeeEeEEeCCceeeEEEEEcCccceehhceEEEeee-eEEEEe--CCc
5708 Confidence 22333333 1 356899988 6689999999999999999999999999988888888777444 467777 999
5709
5710
5711 Q sp|P0DTC2|SPIK 584 ILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNN--SYE 661 (1273)
5712 Q Consensus 584 ilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnn--sye 661 (1273)
5713 +..|+||..+.++++..| ++.++.|++.+||.++.+..+.. +.||-.++. -|||-.||++++...++ ..+
5714 T Consensus 452 ~Y~V~PC~~v~qQvVv~~---~~~vglLt~S~ncn~~~~~~~~~---~~r~~~~~~--~fdt~~Gcv~~~~n~~~~~~~~ 523 (1118)
5715 T 6M15_B 452 VYEVAPCFEASYDVLFRS---SSSFGLLYRSFDCNQLRISASRF---AERLLPSHN--GTATALGCLFNATYAPNDTMVN 523 (1118)
5716 T ss_dssp EEEEECCTTSEEEEEEEE---TTEEEEEETTCCCCHHHHTSSTT---TTTCCGGGC--SEEETTEEEESSEEEEEEEESS
5717 T ss_pred EEEEecCcccceeEEEeC---CCeEEEEEcccccceeeeecccc---ccccCCCCC--CcccceeeEEEeecCCCCCCcc
5718 Confidence 999999999999999988 47899999999998887655544 334443333 39999999999987744 699
5719
5720
5721 Q sp|P0DTC2|SPIK 662 CDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMY 741 (1273)
5722 Q Consensus 662 cdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmy 741 (1273)
5723 |+.|+|.|||+.+ .-.-.+||.+-+ .+. ... .+.....+.|.||+||||+|++|-++++|.|.+|||.+|
5724 T Consensus 524 C~~p~g~giC~dg-~~~~~~r~~~l~------~~~-~~~--v~p~~~~~~IsIPtNFTlsvt~EYIQt~~~kVsVDCa~Y 593 (1118)
5725 T 6M15_B 524 CTNPLGDGFCADL-LSNVVVRRMTFE------KHD-TTY--VAPVTNERFTELPLDHQLVLTEQFLQTTMPKFSISCETY 593 (1118)
5726 T ss_dssp CSSEEETTEEEEC-SSSCEEEEECCC------CBC-CSC--CCCCCSSEEEEEEEEEEEEEEEEEEECCCCEEEECHHHH
5727 T ss_pred CCCCceeeEecCC-cceeceeeeeee------ccc-ccc--ccCcccceeEEccCceEeEEEEEEEeccCCCeEEecchh
5728 Confidence 9999999999999 333334432222 221 111 122334477899999999999999999999999999999
5729
5730
5731 Q sp|P0DTC2|SPIK 742 ICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQI-LPDPS----KPSKRS 816 (1273)
5732 Q Consensus 742 icgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqi-lpdps----kpskrs 816 (1273)
5733 +||++.+|.+||.|||+||..+|+||.+.+..+|.+..+++..+|..... +....|+||||++ +|..+ ++++||
5734 T Consensus 594 VCngn~~C~~LL~QYgs~C~~I~~aL~~~a~led~~~~~~~s~~~~~~~~-~~~~~~~FN~S~~~lp~~~~~~~~~~~RS 672 (1118)
5735 T 6M15_B 594 ICDVSKACKNLLFRYGGFCQKIEADIRGAGVLLDSDVSGLYSTIAAKTSS-ITPTTDRFNVSQFFLPKVQSNSERFESRS 672 (1118)
5736 T ss_dssp HSSSCHHHHTTGGGSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHBBCCCS-SCCBCSSCCCTTTTSCCCCCSSSCCCCCC
5737 T ss_pred ccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHHhhhccC-cCCCCCCccccccccCCCCCCCccccccc
5738 Confidence 99999999999999999999999999999999999999999888766433 3366888999998 67654 346899
5739
5740
5741 Q sp|P0DTC2|SPIK 817 FIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGA--GAAL 894 (1273)
5742 Q Consensus 817 fiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfga--gaal 894 (1273)
5743 +||||||+||..+|.|+.+.|.+|.+ -.+|||+|||.+||+.||||++++||++.|| +.++.||+||+ ++|.
5744 T Consensus 673 ~IEDLLF~KV~t~glG~~~~Yk~Ct~-~~i~DL~CaQyyNGimVLP~v~d~~~~amYT-----asl~ggm~~Ggit~sAa 746 (1118)
5745 T 6M15_B 673 VIEDLLFSKIETTGPGFYGDYYNCKK-NAIQDLTCAQYHNGILVIPPVMDAETLGMYG-----GIAAASLTLGIFGGQAG 746 (1118)
5746 T ss_dssp HHHHHHHHSSCCCCSSHHHHHHHHHH-HCCTTCCCCCEETTEEEECCSSCGGGCCTTS-----STTCBCSSTTTTCSSCC
5747 T ss_pred HHHHHhccceEecCCCchHhHHHhhc-chhhHHhcccccCcEEEcCCCCCHHHHHHHH-----HHHHHHHHhhhhcchhc
5748 Confidence 99999999999999999999999999 6799999999999999999999999999999 44566899988 6789
5749
5750
5751 Q sp|P0DTC2|SPIK 895 QIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAIS 974 (1273)
5752 Q Consensus 895 qipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgais 974 (1273)
5753 .|||||||.||+||+|+||+||.||||+|||.||.|++.||+.++.+++||.|+|||||++++||++|++||+.||||||
5754 T Consensus 747 aiPFa~~vq~RlN~valt~~VL~~NQk~iA~sFN~A~~~iq~~f~tt~~AL~KIQ~VVN~q~~aL~~L~~QL~nnFgAIS 826 (1118)
5755 T 6M15_B 747 ITTWSLAMAGRLNALGVVQNALVDDVNKLANGFNQLTASVGKLALTTSSALQAIQAVVNQNAAQVESLVSGITENFGAIS 826 (1118)
5756 T ss_dssp CCBHHHHHHHHHHHTTSCSSCCHHHHHHHHHHHHHHHHTGGGCCTTTCHHHHHHHHHHHHHHHHHHHHHHTTTSCTTSSC
5757 T ss_pred hhhHHHHHHHHHhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHH
5758 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5759
5760
5761 Q sp|P0DTC2|SPIK 975 SVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQ 1054 (1273)
5762 Q Consensus 975 svlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpq 1054 (1273)
5763 |.++||++|||++||++||||||+|||.+|++||+|||+|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||
5764 T Consensus 827 SSI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtq~l~~~~ev~~sr~LA~qKINECVKSQS~R~GFCGnGtHi~Si~q 906 (1118)
5765 T 6M15_B 827 TNFKVISQRLDKLEADVQMDRLINGRMNVLQLFVTNYKLKIAELRNTHRYVQSLINECVYAQSLRNGFCGQGLHVLSLMQ 906 (1118)
5766 T ss_dssp SCHHHHHHHBCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTTSSSEEEEEEEE
5767 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccCcccCCCCCCeEeEeecc
5768 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5769
5770
5771 Q sp|P0DTC2|SPIK 1055 SAPHGVVFLHVTYVPAQEKNFTTAPAICHD----GKAHFPREGVFVSNG-THWFVTQRNFYEPQIITTDNTFVSGNCDVV 1129 (1273)
5772 Q Consensus 1055 saphgvvflhvtyvpaqeknfttapaichd----gkahfpregvfvsng-thwfvtqrnfyepqiittdntfvsgncdvv 1129 (1273)
5773 .||+|++|+|.+|+|.+-++.+++|.+|++ +++..||+|+|+.+. +.|++|.|++|+|..||.+|.... .||+.
5774 T Consensus 907 ~APnGi~F~H~~y~Pt~~~~V~a~~GlC~~~~~~~~~~~~~~g~f~~~n~~~w~iT~r~my~Pr~it~~d~v~~-sc~v~ 985 (1118)
5775 T 6M15_B 907 NAPSGIMFFHYSLIPNNTITVKTTPGLCESDELGSKCIVAKDGVLVSANLSYWQWSPRNLYKPENLTFANVIAV-SRGAN 985 (1118)
5776 T ss_dssp EETTEEEEEEEEEEEEEEEEEEEESCEESSSSTTCCEEEESSSEEEESSCSSCEEECTTSCCCEECCTTTEEEE-CCCTT
5777 T ss_pred cCCCeEEEEEEEeccCceeEEEEeeeeEccCCCCCcEEEecccEEEEcCCCEEEECccccccCCCCCccCeEEE-ecCce
5778 Confidence 999999999999999999999999999999 457999999999864 999999999999999999998777 78999
5779
5780
5781 Q sp|P0DTC2|SPIK 1130 IGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQY 1209 (1273)
5782 Q Consensus 1130 igivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqy 1209 (1273)
5783 ...+|.++..|..|++-.|+|||+|+|||+++.-.||.+.+ +|++++|++.||++|+|+.|+||+++|||++|++||+|
5784 T Consensus 986 y~~vn~t~~~p~ipd~~Df~eel~e~~kn~s~~~pdl~~~~-~N~T~LNLs~EI~~LqevIk~LN~s~IdLe~L~~~e~Y 1064 (1118)
5785 T 6M15_B 986 YTTLNRTFDIPELNSTFPIDEEFREYFQNMSSELQALKNLT-ADMSKLNISAEIQLINEIAHNVSNMRVEVEKFQRYVNY 1064 (1118)
5786 T ss_dssp CEECSSCCCC----------------------------------------------------------------------
5787 T ss_pred EEEeccccCCCCCcCCCChHHHHHHHHhhcCccccccccce-ecCceechHHHHHHHHHHHHHHHhccccHHHhCeeeEE
5788 Confidence 99999999999999999999999999999988777787766 99999999999999999999999999999999999999
5789
5790
5791 Q sp|P0DTC2|SPIK 1210 IKWPWY 1215 (1273)
5792 Q Consensus 1210 ikwpwy 1215 (1273)
5793 |||.-.
5794 T Consensus 1065 iKW~~~ 1070 (1118)
5795 T 6M15_B 1065 VKLEVL 1070 (1118)
5796 T ss_dssp ------
5797 T ss_pred eeceee
5798 Confidence 999854
5799
5800
5801 No 12
5802 >6JX7_A Feline Infectious Peritonitis Virus Spike; CoV spike protein, VIRAL PROTEIN; HET: NAG, MAN, FUC, BMA; 3.31A {Feline infectious peritonitis virus}
5803 Probab=100.00 E-value=2e-132 Score=1149.25 Aligned_cols=664 Identities=33% Similarity=0.532 Sum_probs=532.7 Template_Neff=4.600
5804
5805 Q sp|P0DTC2|SPIK 525 CGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTN- 603 (1273)
5806 Q Consensus 525 cgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitpgtn- 603 (1273)
5807 -|-...++++.++||++|.-|.+|+|++++++..+... .+-.|...-.++.++..++++..|+||....++|+..|+.
5808 T Consensus 674 ~g~~d~~~i~l~~Cv~YnIYG~tG~GvI~~~~~~~~~G-l~~~s~sG~l~~Fk~~~~~~~Y~V~PC~~~~Q~vV~~~~iV 752 (1468)
5809 T 6JX7_A 674 LGFQDISNIVKDECTDYNIYGFQGTGIIRSTTSRLVAG-LYYTSASGDLLGFKISTTGEIFTVVPCDLTAQAAVINDEIV 752 (1468)
5810 T ss_dssp CSCSSCCCCCBSSEEEEEETTEEEEEEEEECCCCCCSC-SEEECTTSCEEEEECSSSSCEEEEECSSCCEEEEESSSSEE
5811 T ss_pred ceeeccceeEeccceeEEeCCccceEEEEecCeeeeCc-EEEEcCCCCEEEEEeCCCCCEEEEEeCCcCceEEEECCeEE
5812 Confidence 34456789999999999999999999999999888655 6667777778999999999999999999999999999875
5813
5814
5815 Q sp|P0DTC2|SPIK 604 ---TSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNS 680 (1273)
5816 Q Consensus 604 ---tsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipigagicasyqtqtns 680 (1273)
5817 ||...+.+++.+||+++..+.+ .++. ..+.++|-.||.+++.+...+.+|+.++|.|.|+-+.+-.
5818 T Consensus 753 G~ltS~n~~~~~~~~nct~v~~s~~---s~~~------~~~~~~TP~fcy~~~~~~~~~~~c~~~l~yg~~~i~~dG~-- 821 (1468)
5819 T 6JX7_A 753 GAITATNQTDLFEFVNHTWSRSARG---SSPS------TVNTYTMPQFYYITKWNNGTSSNCTSVITYSSFAICNTGE-- 821 (1468)
5820 T ss_dssp EEEESSSCCCSSSCSCC--------------C------CCCEEECSSCEEECSCCSSSCCCCCCCBCCTTEEECTTSC--
5821 T ss_pred EEEEccCcccccccceeeeeeeecc---CCCC------cccceecceeEEEeeccCCccccccceeeeceEEEcCCCc--
5822 Confidence 7788889999999999884433 1111 3455999999999999888899999999999888776621
5823
5824
5825 Q sp|P0DTC2|SPIK 681 PRRARSVASQSIIAYTMSLGAE-NS--VAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYG 757 (1273)
5826 Q Consensus 681 prrarsvasqsiiaytmslgae-ns--vaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqyg 757 (1273)
5827 .+-+ -...+++... .. ..-....|.||+||||+|++|-+.++|.|.+|||.+|+||++.+|.+||.|||
5828 T Consensus 822 ---i~~v-----~~~~~~~~~~~~~~~~~~~t~~v~IP~nFt~~v~~EyiQ~~~~kv~idC~~YVC~~~~~C~~ll~qYg 893 (1468)
5829 T 6JX7_A 822 ---IKYV-----NVTHVEIVDDSVGVIKPVSTGNITIPKNFTVAVQAEYVQIQVKPVAVDCAKYVCNGNRHCLNLLTQYT 893 (1468)
5830 T ss_dssp ---EEEC-----CCEECSSSSCSSSSCCCCCSSEEECCCCEEEEEEEEEECCCCCCEEECHHHHHSSSCHHHHTTGGGGH
5831 T ss_pred ---EEEE-----eceeeeeeeCccccccceeEEEEEecCCeeEEEEEEEEeccCCceEEechhhhcCCCHHHHHHHHHHh
5832 Confidence 1111 0000111000 00 11123478999999999999999999999999999999999999999999999
5833
5834
5835 Q sp|P0DTC2|SPIK 758 SFCTQLNRALTGIAVEQDKNTQEVFAQVKQ-IYKTPPIKDFG-------------GFNFSQILPDPSKPSKRSFIEDLLF 823 (1273)
5836 Q Consensus 758 sfctqlnraltgiaveqdkntqevfaqvkq-iyktppikdfg-------------gfnfsqilpdpskpskrsfiedllf 823 (1273)
5837 +||..+++||.+.+ .+|......+..+.. -++++-+.+|. ++|++.+||.+. ++||+||||||
5838 T Consensus 894 s~C~~I~~al~~~~-~ld~~~~~~~~~~~~~~~~~~~~~~fn~~~~~~~~~g~~~~~~~s~~l~~~~--~~RS~IEDLLF 970 (1468)
5839 T 6JX7_A 894 SACQTIENSLNLGA-RLESLMLNDMITVSDRSLEFATVDKFNTTALGGEKLGGLYFDGLSSLLPPRV--GMRSAVEDLLF 970 (1468)
5840 T ss_dssp HHHHHHHHHHHHHH-HHHHHHHTTTCEECHHHHTTCSTTTTTSCCSSSCCSSCTTHHHHHHHSCSSS--SSCCHHHHHHT
5841 T ss_pred HHHHHHHHHHHHHH-HHHHHhHhhcceeccccccccCcccccCcccCcccccccccCCcccCCCCCC--CCCcHHHHHhc
5842 Confidence 99999999999988 666443334444332 44555565553 267787787654 79999999999
5843
5844
5845 Q sp|P0DTC2|SPIK 824 NKVTLADAGFIK-QYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQM 902 (1273)
5846 Q Consensus 824 nkvtladagfik-qygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqm 902 (1273)
5847 +||..+|.|+++ .|.+|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||. |..||||+||
5848 T Consensus 971 ~KV~t~glg~vd~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~t~----aaaiPFa~~v 1046 (1468)
5849 T 6JX7_A 971 NKVVTSGLGTVDDDYKKCSAGTDVADLVCAQYYNGIMVLPGVVDYNKMAMYTASLIGGMALGSITS----AVAVPFSMQV 1046 (1468)
5850 T ss_dssp TTTTTTTCCCCCCCSTTTTTCSSSCCHHHHHHHTTEEECCCSSCHHHHHHHHHHHHHHHHCCCTTC----CCCCCHHHHH
5851 T ss_pred ccEEecCCCcCCHHHHHccCCccHHHHhCccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhcchhh----eecccHHHHH
5852 Confidence 999999999999 69999999999999999999999999999999999999999999999999996 6679999999
5853
5854
5855 Q sp|P0DTC2|SPIK 903 AYRFNGIGVTQNVLYENQKLIANQFNSAIGKI--------------QDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS 968 (1273)
5856 Q Consensus 903 ayrfngigvtqnvlyenqklianqfnsaigki--------------qdslsstasalgklqdvvnqnaqalntlvkqlss 968 (1273)
5857 .+|+|++|+||+||.||||+|||.||.|||.| |+.++++++||.|+|||||++++||++|++||+.
5858 T Consensus 1047 q~RlN~v~lt~~vL~~NQk~iA~sFN~A~~~it~af~~v~~ai~~t~~gf~t~~~Al~kiQ~VVN~q~~aL~~l~~qL~~ 1126 (1468)
5859 T 6JX7_A 1047 QARLNYVALQTDVLQENQKILANAFNNAIGNITLALGKVSNAITTVSDGFNSMASALTKIQSVVNQQGEALSHLISQLQK 1126 (1468)
5860 T ss_dssp HHHHHTTSCCCSCCHHHHHHHHHHHHHHHHHHHHHHHSCCSCSCCCCSHHHHHHHHHHHHHHHTTTHHHHHHHHHGGGSC
5861 T ss_pred HHHhhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHhhhhhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
5862 Confidence 99999999999999999999999999999999 6668999999999999999999999999999999
5863
5864
5865 Q sp|P0DTC2|SPIK 969 NFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYH 1048 (1273)
5866 Q Consensus 969 nfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyh 1048 (1273)
5867 |||||||.++||.+|||++||++|+||||+|||.+|++||+|+|+|++|+|+|+.||..|+.|||..||+|.+|||.|.|
5868 T Consensus 1127 nFgAISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~LA~qKinECVksQS~R~gFCGnG~H 1206 (1468)
5869 T 6JX7_A 1127 NFQAISSSIAEIYNRLEKVEADAQVDRLITGRLAALNAYVAQTLTQYAEVKASRQLAMEKVNECVKSQSDRYGFCGNGTH 1206 (1468)
5870 T ss_dssp CTTSSCSCHHHHTTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCTTCCCCTTSSSSSSE
5871 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHccccccCCCCCCee
5872 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5873
5874
5875 Q sp|P0DTC2|SPIK 1049 LMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPRE--GVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGN 1125 (1273)
5876 Q Consensus 1049 lmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpre--gvfvsngthwfvtqrnfyepqiittdntfvsgn 1125 (1273)
5877 ++|+||.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..||+ ++|+.+...|++|.|++|||..||.+|...-..
5878 T Consensus 1207 v~S~~q~APnGi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~~~~~~~~~~n~~~~~T~r~~y~Pr~~t~~d~v~~~s 1286 (1468)
5879 T 6JX7_A 1207 LFSLVNSAPDGLLFFHTVLLPTEWEEVTAWSGICVNDTYAYLLKDFDHSIFSYNGTYMVTPRNMFQPRKPQMSDFVQITS 1286 (1468)
5880 T ss_dssp EEEEEEEETTEEEEEEEEEEECCCCEEECBSCEEETTTEEEEESSSSEEEEESSSCEEEEESSSCCCBCCCGGGEEEESC
5881 T ss_pred eEeeeecCCCeEEEEEEEeccCceEEEEEEEEEeecCCeeEEeecCceEEEeeCCEEEEeccccccCCCCCccceEEeec
5882 Confidence 9999999999999999999999999999999999995 7889998 999998889999999999999999999999999
5883
5884
5885 Q sp|P0DTC2|SPIK 1126 CDVVIGIVNNTVYDPLQPEL----DSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRL--------------N 1187 (1273)
5886 Q Consensus 1126 cdvvigivnntvydplqpel----dsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrl--------------n 1187 (1273)
5887 |||...-++.++..+..|++ +.|+|||++++|||++|+.++.. ..+|+++.||+.||++| +
5888 T Consensus 1287 C~v~y~n~~~~~~~~~~p~~~d~n~~~~~~~~~~~~n~t~~~~~~~~-~~~n~t~Lnl~~Ei~~l~~~~~~l~~~~~~~~ 1365 (1468)
5889 T 6JX7_A 1287 CEVTFLNTTHTTFQEIVIDYIDINKTIADMLEQYHSNYTTPELDLQL-EIFNQTKLNLTAEIDQLEQRADNLTNIAHELQ 1365 (1468)
5890 T ss_dssp CCTTSEEECHHHHHHHSTTCCCHHHHHHHHHHHHTC--------------------------------------------
5891 T ss_pred CeeEEEEcccccccccccCccccCHhHHHHHHHhcCCCCCcccccCc-cccccceecHHHHHHHHHHHHHHHHHHHHHHH
5892 Confidence 99999999999999999999 99999999999999999997765 88999999999999997 9
5893
5894
5895 Q sp|P0DTC2|SPIK 1188 EVAKNLNESLIDLQELGKYEQYIKWPWYI 1216 (1273)
5896 Q Consensus 1188 evaknlneslidlqelgkyeqyikwpwyi 1216 (1273)
5897 |+.|+||+++|||++|++||+||||||.-
5898 T Consensus 1366 ~~i~~lN~s~idLe~L~~~e~YiKWPW~~ 1394 (1468)
5899 T 6JX7_A 1366 QYIDNLNKTIVDLEWLNRIETYVKWPGSG 1394 (1468)
5900 T ss_dssp -----------------------------
5901 T ss_pred HHHHHHHhcCccHHHHceeEeEecCcccc
5902 Confidence 99999999999999999999999999963
5903
5904
5905 No 13
5906 >5SZS_A Spike glycoprotein; coronavirus, viral fusion protein, vaccine; HET: MAN, NAG, BMA; 3.4A {Human coronavirus NL63}
5907 Probab=100.00 E-value=7.1e-131 Score=1128.95 Aligned_cols=662 Identities=31% Similarity=0.515 Sum_probs=529.3 Template_Neff=4.500
5908
5909 Q sp|P0DTC2|SPIK 505 YQPYRVVVLSFE----LLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQ 580 (1273)
5910 Q Consensus 505 yqpyrvvvlsfe----llhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpq 580 (1273)
5911 ++.+..|-+++. ...+|..+.|-...+++..++||++|.-|.+|+|++++++..+...+.+ .+.+.-..++++..
5912 T Consensus 575 ~~~~~~VYVt~s~GsrItgv~~p~~g~~d~~~i~l~~CvdYnIYG~tG~GvI~n~n~~~~~Gl~~-tS~sg~l~~fk~~~ 653 (1325)
5913 T 5SZS_A 575 YTIVGALYVTWSEGNSITGVPYPVSGIREFSNLVLNNCTKYNIYDYVGTGIIRSSNQSLAGGITY-VSNSGNLLGFKNVS 653 (1325)
5914 T ss_dssp EEEEEEEEECCEEEEEEEECSSCCCSCSSCCBCCCSSCEEEEETTEEEEEEEEEECCCCCSCSEE-ECTTSCEEEEECTT
5915 T ss_pred EEEEEEEEEEecCCCeeEcccccccceeccceEEeCeeeeeEeCCccceeEEEeeceeeeCCEEE-EcCCCCEEEEEcCC
5916 Confidence 666677777765 5556666888888999999999999999999999999999999888888 78888888999999
5917
5918
5919 Q sp|P0DTC2|SPIK 581 TLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAG-CLIGAEHVNN- 658 (1273)
5920 Q Consensus 581 tleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtrag-cligaehvnn- 658 (1273)
5921 ++++..|+||..+.++|+..|+. ..+.+ ..|++.-+ ..|.|+|-.| |..++++.-+
5922 T Consensus 654 ~g~~Y~V~PC~~~~Q~VV~~g~~---vGalt--s~n~~~~~-----------------fnn~~~t~~~~~~s~~~~n~t~ 711 (1325)
5923 T 5SZS_A 654 TGNIFIVTPCNQPDQVAVYQQSI---IGAMT--AVNESRYG-----------------LQNLLQLPNFYYVSNGGNNCTT 711 (1325)
5924 T ss_dssp SSCEEEEECSSCCEEEEEETTEE---EEEEE--SSSSCCSS-----------------CCEEEEETTEEEEESCCSCCSC
5925 T ss_pred CCCEEEEEeCCCCCeEEEECCce---eEEEE--ceeceecC-----------------CCcceecCCcEEEecCCcccCC
5926 Confidence 99999999999999999998762 22222 22222111 3467778888 7777644433
5927
5928
5929 Q sp|P0DTC2|SPIK 659 -SYECDIPIGAGICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVD 737 (1273)
5930 Q Consensus 659 -syecdipigagicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvd 737 (1273)
5931 ..+| .|.|||+.+......|++. ....+ .. -....|.||+|||++|++|-++.+|.|.+||
5932 T Consensus 712 ~v~ty---~~~giC~dg~~~~~~~~~~---~~~~~--------~~----~~t~~i~IP~nft~~v~~EyiQ~~~~kv~iD 773 (1325)
5933 T 5SZS_A 712 AVMTY---SNFGICADGSLIPVRPRNS---SDNGI--------SA----IITANLSIPSNWTTSVQVEYLQITSTPIVVD 773 (1325)
5934 T ss_dssp EEEEE---TTEEEETTSCEEECCCCBC---CCCCC--------CC----SSSEEEEEEEEEEEEEEEEEEECCCCCEEEC
5935 T ss_pred cchhc---ccceEeeCCCccccccccC---CCCCc--------ee----ceeeeEEccCceEEEEEEEEeeccCCCeEEe
5936 Confidence 3455 8999999998775555321 11111 00 1112799999999999999999999999999
5937
5938
5939 Q sp|P0DTC2|SPIK 738 CTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVK---QIYKTPPIKDFGGFNFSQILPDPSKP-- 812 (1273)
5940 Q Consensus 738 ctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvk---qiyktppikdfggfnfsqilpdpskp-- 812 (1273)
5941 |.+|+||++.+|.+||.|||+||..+++||.+.+..++. |++..++ +.+..+.+..|++|||+.+||.+..+
5942 T Consensus 774 C~~YVC~~~~~C~~ll~qYgs~C~~I~~al~~~~~~~~~---~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l~~~~~~~~ 850 (1325)
5943 T 5SZS_A 774 CATYVCNGNPRCKNLLKQYTSACKTIEDALRLSAHLETN---DVSSMLTFDSNAFSLANVTSFGDYNLSSVLPQRNIRSS 850 (1325)
5944 T ss_dssp TTTTTSTTCTTHHHHGGGGHHHHHHHHHHHHHHHHHHHH---HHHHHCCBCHHHHHHTCGGGTGGGCCTTTSCCSCCSSS
5945 T ss_pred chhhccCCCHHHHHHHHHHhHHHHHHHHHHHHHHHHhhH---HHHhhhccCCcccccccccccCCCcchhccCCCCCCCc
5946 Confidence 999999999999999999999999999999999988754 4444444 34455678999999999999998754
5947
5948
5949 Q sp|P0DTC2|SPIK 813 --SKRSFIEDLLFNKVTLADAGFIK-QYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFG 889 (1273)
5950 Q Consensus 813 --skrsfiedllfnkvtladagfik-qygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfg 889 (1273)
5951 +.||+||||||+||..+|.|+++ .|..|.+...+|||+|||.+||+.||||++++||+|.||++|++|....|||.
5952 T Consensus 851 ~~~~RS~IEDLLF~KV~t~glg~vd~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~ta- 929 (1325)
5953 T 5SZS_A 851 RIAGRSALEDLLFSKVVTSGLGTVDVDYKSCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGMVLGGLTS- 929 (1325)
5954 T ss_dssp CSCCCCHHHHHHHHHHC-------CCCGGGGGSCSSCCCHHHHHHTTTEEECCCSSCHHHHHHHHHHHHHTTTCCSBST-
5955 T ss_pred ccCcccHHHHHHCCceeecCCCccchhhHHccCCccHHHHhcccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhhchHH-
5956 Confidence 89999999999999999999997 99999999999999999999999999999999999999999999999999997
5957
5958
5959 Q sp|P0DTC2|SPIK 890 AGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQN 955 (1273)
5960 Q Consensus 890 agaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqn 955 (1273)
5961 |..||||+||.+|+||+|+||+||.||||+|||.||.|||.||.. ++++|+||.|+|||||++
5962 T Consensus 930 ---aaaiPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sFN~A~~~i~~~f~~vn~ai~qts~~~~tv~~Al~kiQ~VVN~q 1006 (1325)
5963 T 5SZS_A 930 ---AAAIPFSLALQARLNYVALQTDVLQENQKILAASFNKAINNIVASFSSVNDAITQTAEAIHTVTIALNKIQDVVNQQ 1006 (1325)
5964 T ss_dssp ---TCCCCHHHHHHHHHHTTSCCCCSSCHHHHHHHHHHHHHHHHHHHHHHC--------CTHHHHHHHHHHHHHHHHHHH
5965 T ss_pred ---hhhChHHHHHHHHhhHhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHH
5966 Confidence 556899999999999999999999999999999999999999988 445669999999999999
5967
5968
5969 Q sp|P0DTC2|SPIK 956 AQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLG 1035 (1273)
5970 Q Consensus 956 aqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlg 1035 (1273)
5971 ++||++|++||+.|||||||.++||.+|||++||++|+||||+|||.+|++||+|+|.|++|+|+|+.||..|+.|||..
5972 T Consensus 1007 ~~aL~~l~~qL~~nFgAISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~LA~qKinECVks 1086 (1325)
5973 T 5SZS_A 1007 GSALNHLTSQLRHNFQAISNSIQAIYDRLDSIQADQQVDRLITGRLAALNAFVSQVLNKYTEVRGSRRLAQQKINECVKS 1086 (1325)
5974 T ss_dssp HHHHHHHHHGGGCCCSSSCSCHHHHHTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
5975 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHc
5976 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
5977
5978
5979 Q sp|P0DTC2|SPIK 1036 QSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVS--NGTHWFVTQRNFYEP 1112 (1273)
5980 Q Consensus 1036 qskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvs--ngthwfvtqrnfyep 1112 (1273)
5981 ||+|.+|||.|.|++|+||.||+|++|+|.+|+|.+-++.+++|.+|+++ ++..||++.|+- +...|++|.|++|||
5982 T Consensus 1087 QS~R~gFCGnG~Hi~S~~q~APnGi~F~H~~~~Pt~~~~v~a~~GlC~~~~~~~~~~~~~~v~~~~n~~~~~T~r~~y~P 1166 (1325)
5983 T 5SZS_A 1087 QSNRYGFCGNGTHIFSIVNSAPDGLLFLHTVLLPTDYKNVKAWSGICVDGIYGYVLRQPNLVLYSDNGVFRVTSRVMFQP 1166 (1325)
5984 T ss_dssp CCCCTTSSSSSEEEEEEEEEETTEEEEEEEEEEEEEEEEEEEESCEEETTTEEEEESSTTEEEEEETTEEEEEESSSCCC
5985 T ss_pred cCcCcCCCCCCeeeEEeeecCCCeEEEEEEeecccceeEEEEEEEEeecCCeeEEecCCCeEEEecCCEEEEeccccccC
5986 Confidence 99999999999999999999999999999999999999999999999995 789999996655 777999999999999
5987
5988
5989 Q sp|P0DTC2|SPIK 1113 QIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPD-VDLGDISGINASVVNIQKEIDR------ 1185 (1273)
5990 Q Consensus 1113 qiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspd-vdlgdisginasvvniqkeidr------ 1185 (1273)
5991 ..||.++...-..|||...-++.++..+..|+.-.|++||+|+||++++.. .|+ ++..+|+.+.|+..||++
5992 T Consensus 1167 r~~t~~d~v~~~sc~v~y~n~~~~~~~~~~p~~~d~~~el~~~~~~~~~~~~p~~-~~~~~n~t~lnl~~ei~~L~~~~~ 1245 (1325)
5993 T 5SZS_A 1167 RLPVLSDFVQIYNCNVTFVNISRVELHTVIPDYVDVNKTLQEFAQNLPKYVKPNF-DLTPFNLTYLNLSSELKQLEAKTA 1245 (1325)
5994 T ss_dssp BCCCGGGEEECSCCCSSSEEECTTGGGGTSTTCCCHHHHHHHC-------------------------------------
5995 T ss_pred cCCCccceEEeeccceEEEEccceecCCCCCCCCChHHHHHHHHHcCCCCCCCCC-CcccccceecchHHHHHHHHHHHh
5996 Confidence 999999999999999999999999999999999999999999999987655 455 378899999999999999
5997
5998
5999 Q sp|P0DTC2|SPIK 1186 --------LNEVAKNLNESLIDLQELGKYEQYIKWPWY 1215 (1273)
6000 Q Consensus 1186 --------lnevaknlneslidlqelgkyeqyikwpwy 1215 (1273)
6001 |+++.|+||+++|||++|++||+||||---
6002 T Consensus 1246 ~l~~~~~~l~~~i~~lN~s~idLe~L~~~e~YiKW~~~ 1283 (1325)
6003 T 5SZS_A 1246 SLFQTTVELQGLIDQINSTYVDLKLLNRFENLIKRMKQ 1283 (1325)
6004 T ss_dssp --------------------------------------
6005 T ss_pred hHHHHHHHHHHHHHHHHHhccCHHHhcHHHHHHHHHHH
6006 Confidence 999999999999999999999999999643
6007
6008
6009 No 14
6010 >6IXB_B Spike glycoprotein; Alphacoronavirus, spike glycoprotein, STRUCTURAL PROTEIN; HET: MAN, NAG, BMA;{Human coronavirus 229E}
6011 Probab=100.00 E-value=8.3e-129 Score=1101.71 Aligned_cols=647 Identities=34% Similarity=0.594 Sum_probs=512.2 Template_Neff=4.700
6012
6013 Q sp|P0DTC2|SPIK 518 LHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSV 597 (1273)
6014 Q Consensus 518 lhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsv 597 (1273)
6015 ..+|..+.|-...++++.++||++|.-|.+|+|++++++..+...+.+ .|...-.++.++..++++..|+||....++|
6016 T Consensus 426 ~gv~~p~~~~~d~~~i~l~~Cv~YnIYG~tG~GvI~~~n~~~~~gl~~-~s~sG~l~~Fk~~~~g~~Y~V~PC~~~~q~V 504 (1116)
6017 T 6IXB_B 426 TGVPQPVEGVSSFMNVTLDKCTKYNIYDVSGVGVIRVSNDTFLNGITY-TSTSGNLLGFKDVTKGTIYSITPCNPPDQLV 504 (1116)
6018 T ss_dssp EECSSSCCCSCCCCCCCCSSCEEEEETTEEEEEEEEEECCCCCSCSEE-ECSSSCEEEEECTTTSCEEEEEESSCCEEEE
6019 T ss_pred EeecccccccccceeEEeCeeeeeEecCccceEEEEeeCceeeCcEEE-EeCCCCEEEEEcCCCCcEEEEeeCCCCCeEE
6020 Confidence 345555788888999999999999999999999999999999877777 7888888999999999999999999999999
6021
6022
6023 Q sp|P0DTC2|SPIK 598 ITPGTNTSNQVAVLYQDVNCTEVPV-AIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIP----IGAGICA 672 (1273)
6024 Q Consensus 598 itpgtntsnqvavlyqdvnctevpv-aihadqltptwrvystgsnvfqtragcligaehvnnsyecdip----igagica 672 (1273)
6025 +..| +...+.++.... .+... .+ .+|.+ +++. +| ...|.-| .|.|||+
6026 T Consensus 505 V~~~---~~vgalts~n~~-~~~~~~~~----~~~~~---------~~~~----~~------~~n~~~~~~~~~~~giC~ 557 (1116)
6027 T 6IXB_B 505 VYQQ---AVVGAMLSENFT-SYGFSNVV----ELPKF---------FYAS----NG------TYNCTDAVLTYSSFGVCA 557 (1116)
6028 T ss_dssp ECSS---SEEEEECSSCCC-CSSSSCCC----CCSSS---------CCBC----CS------CCCCCCEEEEETTEEEET
6029 T ss_pred EeCC---ceEEEEEccccc-cccccceE----Eecee---------eecc----CC------ccccccceeeeceeeEee
6030 Confidence 9988 345566676655 22211 11 12322 1211 23 3333334 4899999
6031
6032
6033 Q sp|P0DTC2|SPIK 673 SYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNL 752 (1273)
6034 Q Consensus 673 syqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnl 752 (1273)
6035 .+....-.|| .+...++ +.-....|.||+|||++|++|-+..+|.|.+|||.+|+||++.+|.+|
6036 T Consensus 558 ~g~~~~~~~~---~~~~~~~------------~~~~t~~v~IP~nft~~v~~Eyiq~~~~kv~idC~~YVC~~~~~C~~l 622 (1116)
6037 T 6IXB_B 558 DGSIIAVQPR---NVSYDSV------------SAIVTANLSIPSNWTTSVQVEYLQITSTPIVVDCSTYVCNGNVRCVEL 622 (1116)
6038 T ss_dssp TSCEECCCCC---BCCCCCC------------CCSCCEEEEEECCCCCCCEEEEEECCCCCEEECHCCCCCSSCHHHHHH
6039 T ss_pred CCCeeeecce---eccCCCC------------ccccceeEEccCCeeeeeEEEEeeccCCCeEEechhhccCCCHHHHHH
6040 Confidence 8876533332 2211111 111122599999999999999999999999999999999999999999
6041
6042
6043 Q sp|P0DTC2|SPIK 753 LLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSK----PSKRSFIEDLLFNKVTL 828 (1273)
6044 Q Consensus 753 llqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfggfnfsqilpdpsk----pskrsfiedllfnkvtl 828 (1273)
6045 |.|||+||..+++||.+.+..+|....+++...++-++.+.+..|++||||.+||.+.. ++.||+||||||+||..
6046 T Consensus 623 l~qYgs~C~~I~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l~~~~~~~~~~~~RS~iEDlLF~KV~t 702 (1116)
6047 T 6IXB_B 623 LKQYTSACKTIEDALRNSAMLESADVSEMLTFDKKAFTLANVSSFGDYNLSSVIPSLPRSGSRVAGRSAIEDILFSKLVT 702 (1116)
6048 T ss_dssp HHHTHHHHHHHHHHHHHHHHHHHHHHHHHCCBCHHHHHTTCGGGGGGGCCTTTSCCCCSSCCC----CHHHHHHHHTCCC
6049 T ss_pred HHHhhhHHHHHHHHHHHHHhhhcHHHHHHHhcCccccccccccccCCccccccccCCCCCCCccccccHHHHHHccceee
6050 Confidence 99999999999999999999999999999999999999999999999999999998753 35799999999999999
6051
6052
6053 Q sp|P0DTC2|SPIK 829 ADAGFIKQ-YGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFN 907 (1273)
6054 Q Consensus 829 adagfikq-ygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfn 907 (1273)
6055 +|.|++++ |.+|.+....|||+|||.+||+.||||.+++||++.||++|++|....|||. |..||||+||.+|+|
6056 T Consensus 703 ~glg~vd~dY~~C~~g~~i~DL~CaQ~ynGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~t~----aaaiPFa~~vq~RlN 778 (1116)
6057 T 6IXB_B 703 SGLGTVDADYKKCTKGLSIADLACAQYYNGIMVLPGVADAERMAMYTGSLIGGIALGGLTS----AASIPFSLAIQSRLN 778 (1116)
6058 T ss_dssp ------CCCGGGTSSSSSCCCHHHHHHHTTEEECCCTTCHHHHHHHHHHHHHHHSCCSCSS----SSCCCGGGHHHHHHH
6059 T ss_pred cCCCcccHHHHHhcCCccHHHHhcccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhhchhH----hhhChHHHHHHHHhh
6060 Confidence 99999988 9999999999999999999999999999999999999999999999999997 556899999999999
6061
6062
6063 Q sp|P0DTC2|SPIK 908 GIGVTQNVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAI 973 (1273)
6064 Q Consensus 908 gigvtqnvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgai 973 (1273)
6065 |+|+||+||.||||+||+.||.|||.||+. ++++|+||.|+|||||++++||++|++||+.|||||
6066 T Consensus 779 ~~~l~~~vL~~NQ~~iA~sFN~A~~~i~~~f~~~n~ai~qts~~~~t~~~Al~kiQ~VVN~~~~aL~~l~~qL~~nFgAI 858 (1116)
6067 T 6IXB_B 779 YVALQTDVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAI 858 (1116)
6068 T ss_dssp HHSCCCCSCCHHHHHHHHHHHHHHHHHHHHHC---------CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCSSSS
6069 T ss_pred hhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6070 Confidence 999999999999999999999999999987 455669999999999999999999999999999999
6071
6072
6073 Q sp|P0DTC2|SPIK 974 SSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFP 1053 (1273)
6074 Q Consensus 974 ssvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfp 1053 (1273)
6075 ||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+|
6076 T Consensus 859 Sssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~lA~qKinECVksQS~R~gFCGnG~Hv~S~~ 938 (1116)
6077 T 6IXB_B 859 SSSIQAIYDRLDIIQADQQVDRLITGRLAALNVFVSHTLTKYTEVRASRQLAQQKVNECVKSQSKRYGFCGNGTHIFSLV 938 (1116)
6078 T ss_dssp CSCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCTSCCSCTTTSSSSEEEEEEE
6079 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCcCcCCCCCCeeEEEee
6080 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6081
6082
6083 Q sp|P0DTC2|SPIK 1054 QSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGV--FVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVI 1130 (1273)
6084 Q Consensus 1054 qsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregv--fvsngthwfvtqrnfyepqiittdntfvsgncdvvi 1130 (1273)
6085 |.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..||++. |+.++.+|++|.|++|||..||..|...-..|||..
6086 T Consensus 939 q~AP~Gi~F~H~~~~P~~~~~v~a~~GlC~~~~~~~~~~~~~~~~~~~~~~~~~T~r~~y~Pr~~t~~d~v~~~~c~v~y 1018 (1116)
6087 T 6IXB_B 939 NAAPEGLVFLHTVLLPTQYKDVEAWSGLCVDGRNGYVLRQPNLALYKEGNYYRITSRIMFEPRIPTIADFVQIENCNVTF 1018 (1116)
6088 T ss_dssp EEETTEEEEEEEEECCSSEEEEEECSCCCCSSSCCCCCSSTTBCCBCSSSSCBCCBSSCCCCCCCCGGGCCCCCCCCTTS
6089 T ss_pred ecCCCeEEEEEEeeccceeEEEEEEEEEeecCCceEEecCCceEeEeeCCEEEEeccccccCCCCCccceEEeecCceeE
6090 Confidence 99999999999999999999999999999995 789999887 888888999999999999999999999999999999
6091
6092
6093 Q sp|P0DTC2|SPIK 1131 GIVNNTVYDPLQPELDSFKEELDKY-FKN--HTSPDVDLGDISGINASVVNIQKEIDR--------------LNEVAKNL 1193 (1273)
6094 Q Consensus 1131 givnntvydplqpeldsfkeeldky-fkn--htspdvdlgdisginasvvniqkeidr--------------lnevaknl 1193 (1273)
6095 .-++.++..+..|+.-.|++||+|+ +|+ |+-||.+ +..+|+.+.|+..||++ |+|+.|+|
6096 T Consensus 1019 ~~~~~~~~~~~~~~~~d~~~~~~~~~~~~~~~~~p~~~---~~~~n~t~lnl~~ei~~L~~~~~~l~~~~~~l~~~i~~l 1095 (1116)
6097 T 6IXB_B 1019 VNISRSELQTIVPEYIDVNKTLQELSYKLPNYTVPDLV---VEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNI 1095 (1116)
6098 T ss_dssp CCCCTTTHHHHSCCC-----------------------------------------------------------------
6099 T ss_pred EEcchhhcCCCCCCCCChHHHHHHHHhhCCCCCCCCCc---HHhccceeechHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6100 Confidence 9999999999999999999999999 664 4556554 77899999999999999 99999999
6101
6102
6103 Q sp|P0DTC2|SPIK 1194 NESLIDLQELGKYEQYIKWPW 1214 (1273)
6104 Q Consensus 1194 neslidlqelgkyeqyikwpw 1214 (1273)
6105 |+++|||++|++||+||||||
6106 T Consensus 1096 N~s~idLe~L~~~e~YiKWPW 1116 (1116)
6107 T 6IXB_B 1096 NSTLVDLKWLNRVETYIKWPW 1116 (1116)
6108 T ss_dssp ---------------------
6109 T ss_pred HhcCccHHHhCeEEEEecCCC
6110 Confidence 999999999999999999999
6111
6112
6113 No 15
6114 >6CV0_A Spike protein; infectious bronchitis coronavirus, spike, pre-fusion; HET: NAG;{Infectious bronchitis virus}
6115 Probab=100.00 E-value=2.9e-125 Score=1068.92 Aligned_cols=651 Identities=31% Similarity=0.547 Sum_probs=514.4 Template_Neff=4.200
6116
6117 Q sp|P0DTC2|SPIK 524 VCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNK------KFLPFQQFGRDIADTTDAV--RDPQTLEILDITPCSFGGV 595 (1273)
6118 Q Consensus 524 vcgpkkstnlvknkcvnfnfngltgtgvltesnk------kflpfqqfgrdiadttdav--rdpqtleilditpcsfggv 595 (1273)
6119 +.|....++++.++||++|.-|.+|+|++++.+. -....+.+-.|.....|.. ++..++++..|+||....+
6120 T Consensus 399 v~g~~d~snI~ld~CvdYNIYG~tG~GvItnvt~s~~~~~yl~~~Gl~ildtSg~idlf~~Kn~~~g~~Y~V~PC~~V~~ 478 (1105)
6121 T 6CV0_A 399 VITRHNYNNITLNTCVDYNIYGRTGQGFITNVTDSAVSYNYLADAGLAILDTSGSIDIFVVQGEYGLTYYKVNPCEDVNQ 478 (1105)
6122 T ss_dssp SCCSCCSCCCCCSSCEEEEETTEEEEEEEEECTTTTTTTTCSCSSCCCEECGGGCEEEEEECSSSSCEEEEEEECTTSSE
6123 T ss_pred cccccccceeEeCeeeeEEecCceeeEEEEecCCccccceeeccCCeEEEeCCCCceEEEEEcCCCCcEEEEEeCccCce
6124 Confidence 6777888999999999999999999999999655 3334444444444445544 4478999999999999999
6125
6126
6127 Q sp|P0DTC2|SPIK 596 SVITPGTNTSNQVAVL-YQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNN--SYECDIPIGAGICA 672 (1273)
6128 Q Consensus 596 svitpgtntsnqvavl-yqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnn--syecdipigagica 672 (1273)
6129 +++..|. +-|++| +....|.++..-.. .+++-.|| +++...+. ..+|+++.|.++|.
6130 T Consensus 479 Q~VV~~~---~iVG~LTs~n~t~s~~~~n~~----------------~i~~~~g~-~~~~~s~~~~~~~c~~~~y~~~ci 538 (1105)
6131 T 6CV0_A 479 QFVVSGG---KLVGILTSRNETGSQLLENQF----------------YIKITNGT-RRFRRSITENVANCPYVSYGKFCI 538 (1105)
6132 T ss_dssp EEEEETT---EEEEEEESSCSSCSEECSSSE----------------ECCCCCSS-SCCCCCCCCCBSCCCSCBCSSEEE
6133 T ss_pred eEEEECC---EEEEEEEEeCCCcccceeceE----------------EEEeeCCc-ceeeecccCccccCcceeecceEE
6134 Confidence 9998887 788888 88888877543111 26777888 77665543 68899999999998
6135
6136
6137 Q sp|P0DTC2|SPIK 673 SYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNL 752 (1273)
6138 Q Consensus 673 syqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnl 752 (1273)
6139 -+... ++. +..+.+..|.+- +.-+...|.||+|||++|++|-+..+|.|.+|||.+|+||++.+|.+|
6140 T Consensus 539 ~~~g~----~~~--~~~~~l~~~~~p------~~~~~~~v~IP~nFtl~v~~EyiQt~~~kV~IDC~~YVC~~~~~C~~l 606 (1105)
6141 T 6CV0_A 539 KPDGS----IAT--IVPKQLEQFVAP------LLNVTENVLIPNSFNLTVTDEYIQTRMDKVQINCLQYVCGNSLDCRDL 606 (1105)
6142 T ss_dssp CSSSC----EEE--BCCCCCCCCCCC------CCCSSCCEEEESSCCCCEEEEEEECCCCEEEECHHHHHSCSCSSSHHH
6143 T ss_pred cCCCC----eee--eccceeeecccc------cceeeeEEEccCceeEeEEEEEEeecCCceEEEchhhccCCCHHHHHH
6144 Confidence 77651 111 111222223222 122566799999999999999999999999999999999999999999
6145
6146
6147 Q sp|P0DTC2|SPIK 753 LLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQI-YKTPPIKDF--GGFNFSQILPDPSKPSKRSFIEDLLFNKVTLA 829 (1273)
6148 Q Consensus 753 llqygsfctqlnraltgiaveqdkntqevfaqvkqi-yktppikdf--ggfnfsqilpdpskpskrsfiedllfnkvtla 829 (1273)
6149 |.|||+||..+++||.+.+..+|.+..+++...|.- +++|-+..| |+||||.+||.|++|++||+||||||+||..+
6150 T Consensus 607 l~qYgs~C~~I~~al~~~~~~e~~~~~~~~~~~~~~~~~~~~~~~~~~~~fN~s~ll~~~~~~~~RS~IEDLLF~KV~t~ 686 (1105)
6151 T 6CV0_A 607 FQQYGPVCDNILSVVNSIGQKEDMELLNFYSSTKPAGFNTPFLSNVSTGEFNISLLLTTPSSPRRRSFIEDLLFTSVESV 686 (1105)
6152 T ss_dssp HTTCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCSCCCCCCCSCSCCSSCCCTTTSCCSSCSSSCCSHHHHHHTTC---
6153 T ss_pred HHHHHHHHHHHHHHHHHHHhHHhHHHHHHHHhcCCCccccccccccCCCCcceeeecCCCCCcCcccHHHHHhcCceeec
6154 Confidence 999999999999999999999999999999999766 677777645 78999999999999999999999999999999
6155
6156
6157 Q sp|P0DTC2|SPIK 830 DAGFIKQYGDCLGDI--AARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFN 907 (1273)
6158 Q Consensus 830 dagfikqygdclgdi--aardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfn 907 (1273)
6159 |.|+-+.|..|.+.. .+|||+|||.+||+.||||++++||++.||++|++|....|||. |..|||||||.+|+|
6160 T Consensus 687 glg~d~~Y~~Ct~g~~~~i~DL~CAQyyNGimVLP~v~d~~~~amYTasL~g~m~~gg~ta----a~aiPFa~~vq~RlN 762 (1105)
6161 T 6CV0_A 687 GLPTDDAYKNCTAGPLGFLKDLACAREYNGLLVLPPIITAEMQTLYTSSLVASMAFGGITA----AGAIPFATQLQARIN 762 (1105)
6162 T ss_dssp ------CCCCTTSCCCCSSGGGHHHHHTTTEEEECCSSCTTSSTTHHHHHHHHHHHSSSCS----CSSCSSHHHHHHHHT
6163 T ss_pred CCCCcHHHHhccCCCCccHHHHhchhhcCcEEeeCCCCCHHHHHHHHHHHHHHHHhcchhH----hhhCcHHHHHHHHhc
6164 Confidence 999999999999996 79999999999999999999999999999999999999999994 667999999999999
6165
6166
6167 Q sp|P0DTC2|SPIK 908 GIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKV 987 (1273)
6168 Q Consensus 908 gigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkv 987 (1273)
6169 ++|+||+||.||||+||+.||.|||.||+.+.++++||.|+|||||++++||++|++||+.|||||||.++||.+|||++
6170 T Consensus 763 ~v~l~~~vL~~NQk~iA~sFN~A~~~i~~~f~~~~~Al~kiQ~VVN~q~~aL~~l~~qL~~nFgAISssi~dIy~rLd~l 842 (1105)
6171 T 6CV0_A 763 HLGITQSLLLKNQEKIAASFNKAIGRMQEGFRSTSLALQQIQHVVNKQNAILTETMASLNKNFGAISSLIQEIYQQLDAI 842 (1105)
6172 T ss_dssp TTTTCSCCCSSSSHHHHHHHHHHHHHHHHHTTSSCSHHHHHHHHHHHHHHHHTTTTTTSSSCCSSSCSCSTTTTTTSCHH
6173 T ss_pred hhhccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHH
6174 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6175
6176
6177 Q sp|P0DTC2|SPIK 988 EAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTY 1067 (1273)
6178 Q Consensus 988 eaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvty 1067 (1273)
6179 ||++|+||||||||.+|++||+|.+.+.+|.||++.||..|+.|||..||+|.+|||.|.|++|+||.||+|++|+|.+|
6180 T Consensus 843 eAdaQvDRLItGRL~aLna~vt~~~~~~~~v~~sr~LA~qKiNECVksQS~R~gFCGnG~Hv~S~~q~AP~Gi~F~H~~~ 922 (1105)
6181 T 6CV0_A 843 QANAQVDRLITGRLSSLSVLASAKQAEHIRVSQQRELATQKINECVKSQSIRYSFCGNGRHVLTIPQNAPNGIVFIHFSY 922 (1105)
6182 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCTTCCCCTTSSSSSSCCCEEEEECSSEEEEEEECC
6183 T ss_pred HHHHHhHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccCcccCCCCCCeEEEeeeeccCCeEEEEEEEe
6184 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6185
6186
6187 Q sp|P0DTC2|SPIK 1068 VPAQEKNFTTAPAICHDG-----KAHFPR--EGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDP 1140 (1273)
6188 Q Consensus 1068 vpaqeknfttapaichdg-----kahfpr--egvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp 1140 (1273)
6189 +|.+-++.+++|.+|.++ .+..|+ .|+|+.+...|++|.|++|||..||.+|...-..|||...-+|+++..|
6190 T Consensus 923 ~P~~~~~v~a~~G~C~~~~~~~~~~~~~~~~~g~~~~~n~~~~~T~r~~y~Pr~~t~~d~v~i~sC~v~y~~~~~~~l~~ 1002 (1105)
6191 T 6CV0_A 923 TPDSFVNVTAIVGFCVKPANASQYAIVPANGRGIFIQVNGSYYITARDMYMPRAITAGDIVTLTSCQANYVSVNKTVITT 1002 (1105)
6192 T ss_dssp CCCCEEEECBCCCBCCCCSSSCCCEECCCTTSCCEEEETTEEEECCSSSCCCBCCCTTSCCEESCCCSSSCCCSSCCCCC
6193 T ss_pred ccCceeEEEEEEEEEecCcccccEEEEecCCCcEEEEECCEEEEeccccccCCCCCcccEEEeecCcceEEeCCcccccC
6194 Confidence 999999999999999997 588888 8999999899999999999999999999999999999999999999998
6195
6196
6197 Q sp|P0DTC2|SPIK 1141 -LQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG-KYEQYIKW 1212 (1273)
6198 Q Consensus 1141 -lqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelg-kyeqyikw 1212 (1273)
6199 ..|+.-.|+|||+|+|+++++.-.|+. +-.+|.++.|++.||++|+|+.|+||+| +||+||. |.|.|..-
6200 T Consensus 1003 ~~~pd~~Dfn~el~~~~~~~~~~~p~~~-~~n~n~t~LnLt~Ei~~l~~~i~~lN~s-~dLe~L~~~~~~~~~~ 1074 (1105)
6201 T 6CV0_A 1003 FVDNDDFDFNDELSKWWNDTKHELPDFD-KFNYTVPILDIDSEIDRIQGVIQGLNDS-VDIKQIEDKIEEILSK 1074 (1105)
6202 T ss_dssp CC------------------------------------------------------------------------
6203 T ss_pred CCCcCCCChHHHHHHHHhcCCCCCCCcc-ccccccceechHHHHHHHHHHHHHHHhc-CCHHHHHHHHHHHHHH
6204 Confidence 579999999999999999976445563 3478889999999999999999999999 6999998 77877654
6205
6206
6207 No 16
6208 >6VV5_C Spike glycoprotein; glycoprotein, surface, receptor-binding, membrane fusion; HET: MAN, PAM, BMA, NAG;{Porcine epidemic diarrhea virus}
6209 Probab=100.00 E-value=1.7e-124 Score=1078.65 Aligned_cols=641 Identities=32% Similarity=0.536 Sum_probs=513.8 Template_Neff=4.600
6210
6211 Q sp|P0DTC2|SPIK 521 PATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITP 600 (1273)
6212 Q Consensus 521 patvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp 600 (1273)
6213 |..+.|-....+++.++||++|.-|.+|+|++++++..++..+. -.+.+.-.++.|+..++++..|+||....++|+..
6214 T Consensus 614 ~~pv~g~~d~s~i~l~~Cv~YnIYG~tG~GvI~~t~~~~~~g~~-y~s~~G~l~~Fk~~~~~~~Y~V~PC~~~~Q~vV~~ 692 (1356)
6215 T 6VV5_C 614 PKPFEGVTDVSFMTLDVCTKYTIYGFKGEGIITLTNSSFLAGVY-YTSDSGQLLAFKNVTSGAVYSVTPCSFSEQAAYVD 692 (1356)
6216 T ss_dssp SSCCSSCSCCCBCCCSSEEEEEETTEEEEEEEEECSCCCSSCSE-EECTTSCEEEEECTTTCCEEEEECSSCEEEEEEET
6217 T ss_pred cCCcccccccceeeeCeeeeeEeCCceeeEEEEEcCceecCceE-EEcCCCCEEEEEcCCCCCEEEEEecccCceEEEEC
6218 Confidence 44466777788999999999999999999999999988876666 57777788899999999999999999999999987
6219
6220
6221 Q sp|P0DTC2|SPIK 601 GTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPI----GAGICASYQT 676 (1273)
6222 Q Consensus 601 gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipi----gagicasyqt 676 (1273)
6223 |+ -|+++-. .|++. -+-+++-.|| +.|.+...+|+.|+ |.|||+.+..
6224 T Consensus 693 g~----~Vg~lts-~n~~~--------------------~~~~~~~~~~---~~~~~~~~~c~~p~ltYg~~~ic~~g~~ 744 (1356)
6225 T 6VV5_C 693 DD----IVGVISS-LSSST--------------------FNSTRELPGF---FYHSNDGSNCTEPVLVYSNIGVCKSGSI 744 (1356)
6226 T ss_dssp TE----EEEEEES-CSCCS--------------------SSEEEEETTE---EEEESCCSCCSSEEEEETTEEEETTCCE
6227 T ss_pred CE----EEEEEEe-ecCCC--------------------CCceeecCce---eEecCCCccccceeEEeccceeecCCce
6228 Confidence 76 4555332 23321 1224555577 56667789999999 9999998776
6229
6230
6231 Q sp|P0DTC2|SPIK 677 QTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQY 756 (1273)
6232 Q Consensus 677 qtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqy 756 (1273)
6233 -...+ +.. .... +.-....|.||+|||++|++|-+..+|.|.+|||.+|+||++.+|.+||.||
6234 T Consensus 745 ~~~~~-~~~-------------~~~~--~~~~~~~v~IP~nft~~v~~Eyiq~~~~kv~idC~~YVC~~~~~C~~ll~qY 808 (1356)
6235 T 6VV5_C 745 GYVPS-QSG-------------QVKI--APTVTGNISIPTNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQY 808 (1356)
6236 T ss_dssp EECCC-CCC-------------CCCC--CCCSSEEEEEEESCEEEEEEEEEECCCCCEEECHHHHHSSSCHHHHHHHGGG
6237 T ss_pred eeecC-ccC-------------CCCC--CcccceEEEecCCeEEEEEEEEEeecCCCeEEechhhccCCCHHHHHHHHHh
6238 Confidence 43222 110 0000 1122237899999999999999999999999999999999999999999999
6239
6240
6241 Q sp|P0DTC2|SPIK 757 GSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF--GGFNFSQILPDPS-------KPSKRSFIEDLLFNKVT 827 (1273)
6242 Q Consensus 757 gsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf--ggfnfsqilpdps-------kpskrsfiedllfnkvt 827 (1273)
6243 |+||..+++||.+.+..+|-.......-..+.++.+-+..| |+|||+.+||.+. ++++||+||||||+||.
6244 T Consensus 809 gs~C~~I~~al~~~~~~e~~e~~~~~~~~~~~~~~~~~s~~~~~~~n~s~~l~~~~~~~~~~~~~~~RS~IEDLLF~KV~ 888 (1356)
6245 T 6VV5_C 809 TAACKTIESALQLSARLESVEVNSMLTISDEALQLATISSFNGDGYNFTNVLGVSVYDPASGRVVQKRSFIEDLLFNKVV 888 (1356)
6246 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHTTCSTTTSCCSSCCCTTTSCEEC--------CEECCHHHHHHHHHHC
6247 T ss_pred HHHHHHHHHHHHHHHhhhcHHHHHhHhhCHHHHhhceeecccCCCcceeeecccccCCCCCCCccCCcCHHHHHhccceE
6248 Confidence 99999999999999999855444444444556666666666 7899999999874 33789999999999999
6249
6250
6251 Q sp|P0DTC2|SPIK 828 LADAGFI-KQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRF 906 (1273)
6252 Q Consensus 828 ladagfi-kqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrf 906 (1273)
6253 .+|.|++ +.|.+|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||. |..||||+||.+|+
6254 T Consensus 889 t~glg~vD~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~t~----aaaiPFa~~vq~Rl 964 (1356)
6255 T 6VV5_C 889 TNGLGTVDEDYKRCSNGRSVADLVCAQYYSGVMVLPGVVDAEKLHMYSASLIGGMVLGGFTS----AAALPFSYAVQARL 964 (1356)
6256 T ss_dssp -------CCCCTTTTSCSSCCCHHHHHHHTTEEECCCSSCHHHHHHHHHHHHHGGGCCSSSC----SSCCCHHHHHHHHH
6257 T ss_pred ecCCCCcchhHHHhcCCccHHHHhcccccCcEEEeCCCCCHHHHHHHHHHHHHHHHhcchhh----hhhChHHHHHHHHh
6258 Confidence 9999999 999999999999999999999999999999999999999999999999999997 44799999999999
6259
6260
6261 Q sp|P0DTC2|SPIK 907 NGIGVTQNVLYENQKLIANQFNSAIGKIQDSL--------------SSTASALGKLQDVVNQNAQALNTLVKQLSSNFGA 972 (1273)
6262 Q Consensus 907 ngigvtqnvlyenqklianqfnsaigkiqdsl--------------sstasalgklqdvvnqnaqalntlvkqlssnfga 972 (1273)
6263 |++|+||+||.||||+||+.||.|||.||+.+ +++++||.|+|||||++++||++|++||+.||||
6264 T Consensus 965 N~~~lt~~vL~~NQk~iA~sFN~A~~~i~~~f~~v~~ai~qts~~~~t~~~Al~kiQ~VVN~q~~aL~~l~~qL~~nFgA 1044 (1356)
6265 T 6VV5_C 965 NYLALQTDVLQRNQQLLAESFNSAIGNITSAFESVKEAISQTSKGLNTVAHALTKVQEVVNSQGAALTQLTVQLQHNFQA 1044 (1356)
6266 T ss_dssp HHHSCCCCCSSHHHHHHHHHHHHHHHHHHHHTTTGGGSCCTTTTSTTSHHHHHHHHHHHHHTTTTTHHHHHHGGGCCCSS
6267 T ss_pred hhhHhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6268 Confidence 99999999999999999999999999999886 8899999999999999999999999999999999
6269
6270
6271 Q sp|P0DTC2|SPIK 973 ISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCG-KGYHLMS 1051 (1273)
6272 Q Consensus 973 issvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcg-kgyhlms 1051 (1273)
6273 |||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||..|+.|||..||+|.+||| .|.|++|
6274 T Consensus 1045 ISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vsq~l~~~~~v~~sr~LA~qKinECVksQS~R~gFCGnnG~Hi~S 1124 (1356)
6275 T 6VV5_C 1045 ISSSIDDIYSRLDILSADAQVDRLITGRLSALNAFVAQTLTKYTEVQASRKLAQQKVNECVKSQSQRYGFCGGDGEHIFS 1124 (1356)
6276 T ss_dssp SCSCHHHHHTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTSSSSSEEEEE
6277 T ss_pred HHHHHHHHHHHHHHHHHhhHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCccccCCCCCceEEEE
6278 Confidence 999999999999999999999999999999999999999999999999999999999999999999999999 7999999
6279
6280
6281 Q sp|P0DTC2|SPIK 1052 FPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVS--N----G--THWFVTQRNFYEPQIITTDNTFV 1122 (1273)
6282 Q Consensus 1052 fpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvs--n----g--thwfvtqrnfyepqiittdntfv 1122 (1273)
6283 +||.||.|++|+|.+|+|.+-++.+++|.+|.++ ++..||++.|+- + + ..|++|.|++|||..||..+...
6284 T Consensus 1125 ~~q~APnGi~F~H~~~~P~~~~~v~a~~G~C~~~~~~~~~~~~~~~~~~~~~~n~~~~~~~~T~r~~y~Pr~~t~~d~v~ 1204 (1356)
6285 T 6VV5_C 1125 LVQAAPQGLLFLHTVLVPSDFVDVIAIAGLCVNDEIALTLREPGLVLFTHELQNHTATEYFVSSRRMFEPRKPTVSDFVQ 1204 (1356)
6286 T ss_dssp EEEEETTEEEEEEEEEECSEEEEEEECCCEEETTTEEEEESCTTEEEESCC-------CCEEEETTSCCCBCCCGGGEEE
6287 T ss_pred eccccCceEEEEEEeecccceeEEEEEEEEEeCCCceEEecCCceEEEeecccCCCCCeEEEeccccccCCCCCccceEE
6288 Confidence 9999999999999999999999999999999995 789999988766 3 1 58999999999999999999999
6289
6290
6291 Q sp|P0DTC2|SPIK 1123 SGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHT---SPDVDLGDISGINASVVNIQKEIDRL------------- 1186 (1273)
6292 Q Consensus 1123 sgncdvvigivnntvydplqpeldsfkeeldkyfknht---spdvdlgdisginasvvniqkeidrl------------- 1186 (1273)
6293 -..|||...-++.++..+..|++..|++||+|+||+++ -||.++ ..+|+.+.|++.||++|
6294 T Consensus 1205 ~~sC~v~y~n~~~~~~~~~~p~~~df~~el~~~~~~~~~~~~p~~~~---~~~n~t~Lnl~~ei~~l~~~~~~l~~~~~~ 1281 (1356)
6295 T 6VV5_C 1205 IESCVVTYVNLTRDQLPDVIPDYIDVNKTLDEILASLPNRTGPSLPL---DVFNATYLNLTGEIADLEQRSESLRNTTEE 1281 (1356)
6296 T ss_dssp ESCCCTTSEEECTTTGGGTSTTCCCHHHHHHC------------------------------------------------
6297 T ss_pred eecCeeEEEEcccccCCCCCCCCCChHHHHHHHHHcCCCCCCCCCCh---hcceeeeechHHHHHHHHHHHHHHhchHHH
6298 Confidence 99999999999999999999999999999999999884 455544 47999999999999997
6299
6300
6301 Q sp|P0DTC2|SPIK 1187 -NEVAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
6302 Q Consensus 1187 -nevaknlneslidlqelgkyeqyikwp 1213 (1273)
6303 +|+.|+||+++|||++|++||.+-+|+
6304 T Consensus 1282 l~~~i~~lN~s~idLe~Ln~~etla~~~ 1309 (1356)
6305 T 6VV5_C 1282 LQSLIYNINNTLVDLEWLNRVETGSGYI 1309 (1356)
6306 T ss_dssp ----------------------------
6307 T ss_pred HHHHHHHHHHhccCHHHHcceeecccCC
6308 Confidence 899999999999999999999987765
6309
6310
6311 No 17
6312 >6M3W_B Spike glycoprotein,Spike glycoprotein; spike, post-fusion, SARS-CoV, coronavirus, glycoprotein; HET: NAG;{Human SARS coronavirus}
6313 Probab=100.00 E-value=1.8e-124 Score=1000.40 Aligned_cols=491 Identities=90% Similarity=1.349 Sum_probs=338.6 Template_Neff=3.600
6314
6315 Q sp|P0DTC2|SPIK 706 AYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQV 785 (1273)
6316 Q Consensus 706 aysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqv 785 (1273)
6317 |++...|.||+|||++|++|-+.++|.|.+|||.+|+||++.+|.+||.|||+||..+++||.+.+..+|....+++...
6318 T Consensus 1 ~~~~~~i~IP~nFtl~v~~EyiQ~~~~kV~IDC~~YVC~~~~rC~~LL~QYgs~C~~I~~aL~~~~~led~~~~~~~s~~ 80 (491)
6319 T 6M3W_B 1 AYSNNTIAIPTNFSISITTEVMPVSMAKTSVDCNMYICGDSTECANLLLQYGSFCTQLNRALSGIAAEQDRNTREVFAQV 80 (491)
6320 T ss_dssp CCCCEEEEEEEEEEEEECCCEEECCCCCCCCCHHHHTCSSCHHHHHHHTTSTTHHHHHHHHHHHHC--------------
6321 T ss_pred CCCcceeeccCCeEEEEEEeeeeecCCceEEechhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHhHhHHHHHHHHHH
6322 Confidence 34567799999999999999999999999999999999999999999999999999999999999999999999999999
6323
6324
6325 Q sp|P0DTC2|SPIK 786 KQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLL 865 (1273)
6326 Q Consensus 786 kqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqygdclgdiaardlicaqkfngltvlppll 865 (1273)
6327 ++-++.|-+..|+|||||.++|.++++++||+||||||+||..+|.|+.+.|..|.+....|||+|||.|||+.||||..
6328 T Consensus 81 ~~~~~~~~~~~~~~~N~s~~lp~~~~~~~RS~IEDLLF~KV~t~glG~~~dYk~Ct~g~~i~DL~CaQyyNGimVLP~v~ 160 (491)
6329 T 6M3W_B 81 KQMYKTPTLKYFGGFNFSQILPDPLKPTKRSFIEDLLFNKVTLADAGFMKQYGECLGDINARDLICAQKFNGLTVLPPLL 160 (491)
6330 T ss_dssp --------------------------------------------------------------------------------
6331 T ss_pred hHHhccCcccccCCccccccCCCCCCCCCcCHHHHHhcCceeecCCchhHhHHHccCCccHHHhhcccccCCEEeeCCCC
6332 Confidence 99999999999999999999999988999999999999999999999999999999999999999999999999999999
6333
6334
6335 Q sp|P0DTC2|SPIK 866 TDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASAL 945 (1273)
6336 Q Consensus 866 tdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasal 945 (1273)
6337 ++||++.||++|++|....|||+|+|+|..||||+||.||+||+|+||+||.||||+|||.||.|++.||+.++.+++||
6338 T Consensus 161 d~~~~a~YTasL~g~ma~gg~T~g~~saaaIPFa~~vq~RlN~valtt~VL~~NQk~iA~sFN~A~~~iq~g~~t~~~AL 240 (491)
6339 T 6M3W_B 161 TDDMIAAYTAALVSGTATAGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTAL 240 (491)
6340 T ss_dssp -----------------------------------------------------CCHHHHHHHHHHHHHHHHHHHHHHHHH
6341 T ss_pred CHHHHHHHHHHHHHHHhccccccCcchhccchHHHHHHHHhccccccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6342 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6343
6344
6345 Q sp|P0DTC2|SPIK 946 GKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLA 1025 (1273)
6346 Q Consensus 946 gklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanla 1025 (1273)
6347 .|+|||||++++||++|++||+.|||||||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||
6348 T Consensus 241 ~KiQ~VVN~q~~aL~~L~~qL~nnFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnafVtq~l~~~~ev~~sr~LA 320 (491)
6349 T 6M3W_B 241 GKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLA 320 (491)
6350 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6351 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHH
6352 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6353
6354
6355 Q sp|P0DTC2|SPIK 1026 ATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVT 1105 (1273)
6356 Q Consensus 1026 atkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfpregvfvsngthwfvt 1105 (1273)
6357 ..|+.|||..||+|.+|||.|.|++|+||.||.|++|+|.+|+|.+-++.++.|.+|.++++..|++|+|+.|+..|++|
6358 T Consensus 321 ~qKiNECVKSQS~R~gFCGnGtHi~Si~q~APnGi~F~H~~~~Pt~~~~V~a~~GlC~~~~~~~~~~g~f~~~~~~~~iT 400 (491)
6359 T 6M3W_B 321 ATKMSECVLGQSKRVDFCGKGYHLMSFPQAAPHGVVFLHVTYVPSQERNFTTAPAICHEGKAYFPREGVFVFNGTSWFIT 400 (491)
6360 T ss_dssp HHHCCCCCSSCCCCBTSSSSSEEEEEEEEECSSEEEEEEEEEEEEEEEEEEEBSCCCSSSCCCEETTCCEECSSSCCEEC
6361 T ss_pred HHHHHHHHhccCcCcCcCCCCeeEEeccccCCCeEEEEEEEeCccceeEEEEeceEeecCceEeeeceeEEEcCcEEEEe
6362 Confidence 99999999999999999999999999999999999999999999999999999999999998999999999899999999
6363
6364
6365 Q sp|P0DTC2|SPIK 1106 QRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDR 1185 (1273)
6366 Q Consensus 1106 qrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidr 1185 (1273)
6367 .|++|||..||..|...-..|||...-+|+++.+|++|++..|+|||++|+||+|+|+.++++++.+|+++.|++.||++
6368 T Consensus 401 ~r~my~Pr~~t~~d~V~itsC~V~y~Nvn~~~~~~~~Pdy~df~del~~~~~N~T~p~~~l~~ld~fN~T~LNLt~EI~~ 480 (491)
6369 T 6M3W_B 401 QRNFFSPQIITTDNTFVSGNCDVVIGIINNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDR 480 (491)
6370 T ss_dssp CSSSCCCEECCSSSEECCSSCCCBCCCCCCSCCCCCCCCCCCHHHHHHHSCCCCCCCCCCCSHHHHCCCCCCCCCHHHHH
6371 T ss_pred ccccccCccCCCCceEEeecceeEEEEecccccCCCCCCCCCHHHHHHHHccCCCCCCCCCCCcccccccccchHHHHHH
6372 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6373
6374
6375 Q sp|P0DTC2|SPIK 1186 LNEVAKNLNES 1196 (1273)
6376 Q Consensus 1186 lnevaknlnes 1196 (1273)
6377 |++++++||+|
6378 T Consensus 481 Lq~~i~~Ln~s 491 (491)
6379 T 6M3W_B 481 LNEVAKNLNES 491 (491)
6380 T ss_dssp HHHHHHHHHHC
6381 T ss_pred HHHHHHHHHcC
6382 Confidence 99999999986
6383
6384
6385 No 18
6386 >6U7K_C Spike glycoprotein; PEDV, Spike, Coronavirus, Fusion Protein; HET: MAN, BMA, NAG; 3.14A {Porcine epidemic diarrhea virus (strain CV777)}
6387 Probab=100.00 E-value=1.1e-122 Score=1065.47 Aligned_cols=641 Identities=33% Similarity=0.542 Sum_probs=505.8 Template_Neff=4.600
6388
6389 Q sp|P0DTC2|SPIK 521 PATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITP 600 (1273)
6390 Q Consensus 521 patvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadttdavrdpqtleilditpcsfggvsvitp 600 (1273)
6391 |..+.|-....|++.++||++|..|.+|+|++++++..+...+ +..+.+...++.|+..++++..|+||..+.+.|+..
6392 T Consensus 629 ~~pv~g~~d~sni~l~~CvdYnIYG~tG~GvI~~t~~~~~~g~-~y~s~~G~l~~Fk~~~~~~~Y~V~PC~~~~Q~vv~~ 707 (1399)
6393 T 6U7K_C 629 PKPLEGITDVSFMTLDVCTKYTIYGFKGEGIITLTNSSILAGV-YYTSDSGQLLAFKNVTSGAVYSVTPCSFSEQAAYVN 707 (1399)
6394 T ss_dssp SSCCCCSSCCCBCCCSSEEEEEETTEEEEEEEEEESCCCSSCS-EEECSSSSEEEEECTTTCCEEEEECSSCEEEEEEET
6395 T ss_pred cCCCccccccceeeeCeeEeeEeCCceeeEEEEEcCceeeCce-EEEcCCCCEEEEECCCCCCEEEEEeceeccEEEEEC
6396 Confidence 4446777888999999999999999999999999998887777 889999999999999999999999999887744443
6397
6398
6399 Q sp|P0DTC2|SPIK 601 GTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPI----GAGICASYQT 676 (1273)
6400 Q Consensus 601 gtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragcligaehvnnsyecdipi----gagicasyqt 676 (1273)
6401 |+ -|.++ ...|++. ..| +++-.|| +.|.+...+|+.|+ |.|||+.+..
6402 T Consensus 708 ~~----~vg~l-ts~n~~~-------------------~~~-~~~~~~~---~~~s~~~~~c~~p~ltYg~~~ic~~g~~ 759 (1399)
6403 T 6U7K_C 708 DD----IVGVI-SSLSNST-------------------FNN-TRELPGF---FYHSNDGSNCTEPVLVYSNIGVCKSGSI 759 (1399)
6404 T ss_dssp TE----EEEEE-ESCSCCS-------------------SSE-EEECSSC---EEEESCCSCCSCEEEEETTEEEETTSCE
6405 T ss_pred CE----EEEEe-EeeeCCC-------------------CCC-eeecCce---eEecCCCcccccceEEecCceeeecCcc
6406 Confidence 22 23322 2223321 223 6778888 77888899999999 9999998876
6407
6408
6409 Q sp|P0DTC2|SPIK 677 QTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQY 756 (1273)
6410 Q Consensus 677 qtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqy 756 (1273)
6411 -.-+|+ .+.. .|. . -....|.||+|||++|++|-+.++|.|.+|||.+|+||++.+|.++|.||
6412 T Consensus 760 ~~~~~~-~~~~------~~~--~-------~~~~~v~IP~nft~~v~~Eyiq~~~~kV~VdCnvYVC~~N~rC~~lL~QY 823 (1399)
6413 T 6U7K_C 760 GYVPSQ-YGQV------KIA--P-------TVTGNISIPTNFSMSIRTEYLQLYNTPVSVDCATYVCNGNSRCKQLLTQY 823 (1399)
6414 T ss_dssp EECCCC-BCCC------CCC--C-------CSSSEEEEECSEEEEEEEEEEECCCCCEEECHHHHHHTTCHHHHHHHTTS
6415 T ss_pred ccccCc-cccc------ccc--c-------ccceeEEecCCeEEEEEEEEEeecCCCeEEEceEEEeCCCHHHHHHHHHH
6416 Confidence 433331 1111 110 0 11227899999999999999999999999999999999999999999999
6417
6418
6419 Q sp|P0DTC2|SPIK 757 GSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDF--GGFNFSQILPDPS----K---PSKRSFIEDLLFNKVT 827 (1273)
6420 Q Consensus 757 gsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdf--ggfnfsqilpdps----k---pskrsfiedllfnkvt 827 (1273)
6421 |+||..+|.||.+.+-.++-...+....-.+.++++-+..| ++|||+.++|.+. + ++.||+||||||+||.
6422 T Consensus 824 gs~C~nIn~aL~~s~~le~~E~~~~~t~si~~l~~~~~s~~~~~d~N~s~ll~~~~~~p~~d~~~~~RSvIEDLLF~KV~ 903 (1399)
6423 T 6U7K_C 824 TAACKTIESALQLSARLESVEVNSMLTISEEALQLATISSFNGDGYNFTNVLGASVYDPASGRVVQKRSVIEDLLFNKVV 903 (1399)
6424 T ss_dssp TTHHHHHHHHHHHHHHHHHHHHHHHCCBCHHHHHHHTTSCCCCTTCCCHHHHCC------------CCCHHHHHHHHTTT
6425 T ss_pred HHHHHHHHHHHHHHHhhhhHHHHhhhccCHHHHhhhceeccCCCcceeeeeeccccCCCCCCCcCCcccHHHHHheeceE
6426 Confidence 99999999999998877644333334444555555555444 7899999887542 2 4789999999999999
6427
6428
6429 Q sp|P0DTC2|SPIK 828 LADAGFI-KQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRF 906 (1273)
6430 Q Consensus 828 ladagfi-kqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrf 906 (1273)
6431 .+|.|++ +.|..|.+...+|||+|||.+||+.||||++++||++.||++|++|....|||. |..||||+||.+|+
6432 T Consensus 904 t~glg~vD~~Y~~C~~g~~i~DL~CaQ~yNGi~VLP~v~~~~~~a~YT~sl~g~m~~gg~ta----aaaiPFa~~vq~Rl 979 (1399)
6433 T 6U7K_C 904 TNGLGTVDEDYKRCSNGRSVADLVCAQYYSGVMVLPGVVDAEKLHMYSASLIGGMALGGITA----AAALPFSYAVQARL 979 (1399)
6434 T ss_dssp TTCCSSSCCCGGGGSSCSSCCCHHHHHHHTTEEECCCSSCHHHHHHHHHHHHGGGGCCCSSC----SSCCCHHHHHHHHH
6435 T ss_pred ecCCCCcchhhHHhcCCccHHHHhcccccCcEEEeCCCCCHHHHHhHHHHHHHHHHhcchhH----hhhChHHHHHHHHh
6436 Confidence 9999999 999999999999999999999999999999999999999999999999999997 66799999999999
6437
6438
6439 Q sp|P0DTC2|SPIK 907 NGIGVTQNVLYENQKLIANQFNSAIGKIQDSLS--------------STASALGKLQDVVNQNAQALNTLVKQLSSNFGA 972 (1273)
6440 Q Consensus 907 ngigvtqnvlyenqklianqfnsaigkiqdsls--------------stasalgklqdvvnqnaqalntlvkqlssnfga 972 (1273)
6441 |++|+||+||.||||+||+.||.||+.||+.++ ++++||.|+|||||++++||++|++||+.||||
6442 T Consensus 980 N~~~lt~~vL~~NQk~iA~sFN~A~~~iq~~f~~v~~ai~qts~~~~t~~~Al~kiQ~VVN~~~~aL~~l~~qL~~nFgA 1059 (1399)
6443 T 6U7K_C 980 NYLALQTDVLQRNQQLLAESFNSAIGNITSAFESVKEAISQTSKGLNTVAHALTKVQEVVNSQGSALNQLTVQLQHNFQA 1059 (1399)
6444 T ss_dssp HTTSCCCCCSSTHHHHHHHHHHHHHHHHHTTTTCCGGGCCGGGGSTTSHHHHHHHHHHHHHHTTHHHHHHHHTTSCCTTS
6445 T ss_pred hhhHHchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6446 Confidence 999999999999999999999999999999866 899999999999999999999999999999999
6447
6448
6449 Q sp|P0DTC2|SPIK 973 ISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCG-KGYHLMS 1051 (1273)
6450 Q Consensus 973 issvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskrvdfcg-kgyhlms 1051 (1273)
6451 |||.++||++|||++||++|+||||+|||.+|.+||+|+|+|++|+|+|+.||..|+.|||..||+|.+||| .|.|++|
6452 T Consensus 1060 ISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~LA~qKinECVksQS~R~gFCGnnG~Hv~S 1139 (1399)
6453 T 6U7K_C 1060 ISSSIDDIYSRLDILSADVQVDRLITGRLSALNAFVAQTLTKYTEVQASRKLAQQKVNECVKSQSQRYGFCGGDGEHIFS 1139 (1399)
6454 T ss_dssp SCSCHHHHHTTSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCSTTTTTSSSEEEEE
6455 T ss_pred HHHHHHHHHHHHHHHHHhhHHHHHHhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCccccCCCCCceEEEE
6456 Confidence 999999999999999999999999999999999999999999999999999999999999999999999999 7999999
6457
6458
6459 Q sp|P0DTC2|SPIK 1052 FPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVFVSNG--------THWFVTQRNFYEPQIITTDNTFV 1122 (1273)
6460 Q Consensus 1052 fpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvfvsng--------thwfvtqrnfyepqiittdntfv 1122 (1273)
6461 +||.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..||++.|+-.. ..|++|.|++|||..||.++...
6462 T Consensus 1140 ~~q~APnGi~F~H~~~~P~~~~~v~a~~G~C~~~~~~~~~~~~~~v~~~~~~~~~~~~~~~~T~r~~y~Pr~~t~~d~v~ 1219 (1399)
6463 T 6U7K_C 1140 LVQAAPQGLLFLHTVLVPGDFVNVLAIAGLCVNGEIALTLREPGLVLFTHELQTYTATEYFVSSRRMFEPRKPTVSDFVQ 1219 (1399)
6464 T ss_dssp EEEEETTEEEEEEEEEEESCEEEEEECCCEEETTTEEEEESCTTEEEEESCTTSSSCSCCEEEESSSCCCBCCCTTTEEE
6465 T ss_pred eccccCceEEEEEEEeccCceEEEEEEEEEEecCCeeEEecCCceEEEeeCCcccccceEEEeccccccCCCCCccceEE
6466 Confidence 9999999999999999999999999999999995 78999999766532 48999999999999999999999
6467
6468
6469 Q sp|P0DTC2|SPIK 1123 SGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHT---SPDVDLGDISGINASVVNIQKEIDRLNE----------- 1188 (1273)
6470 Q Consensus 1123 sgncdvvigivnntvydplqpeldsfkeeldkyfknht---spdvdlgdisginasvvniqkeidrlne----------- 1188 (1273)
6471 -..|||...-++.++..+..|++-.|++||+|+||+++ .||.++ ..+|+.+.|++.||++|++
6472 T Consensus 1220 ~~~c~v~y~~~~~~~~~~~~p~~~d~~~~l~~~~~~~~~~~~p~~~~---~~~n~t~lnl~~ei~~l~~~~~~l~~~~~~ 1296 (1399)
6473 T 6U7K_C 1220 IESCVVTYVNLTSDQLPDVIPDYIDVNKTLDEILASLPNRTGPSLPL---DVFNATYLNLTGEIADLEQRSESLRNTTEE 1296 (1399)
6474 T ss_dssp ESSCCTTSEEECTTTHHHHSTTC---------------------------------------------------------
6475 T ss_pred eecCeeEEEEcCcccCCCCCCCCCChHHHHHHHHHcCCCCCCCCCCh---hcceeeeechHHHHHHHHHHHHHHHhHHHH
6476 Confidence 99999999999999999999999999999999999884 455543 4789999999999999877
6477
6478
6479 Q sp|P0DTC2|SPIK 1189 ---VAKNLNESLIDLQELGKYEQYIKWP 1213 (1273)
6480 Q Consensus 1189 ---vaknlneslidlqelgkyeqyikwp 1213 (1273)
6481 +.|+||+++|||++|++||.|+||-
6482 T Consensus 1297 ~~~~i~~lN~s~idLe~L~~~et~~~~~ 1324 (1399)
6483 T 6U7K_C 1297 LRSLINNINNTLVDLEWLNRVETGSGYI 1324 (1399)
6484 T ss_dssp ----------------------------
6485 T ss_pred HHHHHHHHHHhccCHHHHcceeecCccC
6486 Confidence 9999999999999999999999993
6487
6488
6489 No 19
6490 >6BFU_C Spike protein; coronavirus spike glycoprotein, porcine deltacoronavirus; HET: MAN, BMA, NAG; 3.5A {Porcine deltacoronavirus}
6491 Probab=100.00 E-value=3.5e-119 Score=1017.49 Aligned_cols=746 Identities=30% Similarity=0.489 Sum_probs=605.1 Template_Neff=4.700
6492
6493 Q sp|P0DTC2|SPIK 267 VGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQ-PTESIVRFPNITNLCPFGEVFNAT 345 (1273)
6494 Q Consensus 267 vgylqprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvq-ptesivrfpnitnlcpfgevfnat 345 (1273)
6495 +.|...-..|+ |-.||+|.|.+.|--.|+..-||.-.+|....|.|..++..+. ..+.+|..|+..+....- .|.+
6496 T Consensus 240 va~a~~tdVL~-~f~ngtIq~viyCD~sp~~~LaCqy~tfnfsDGFYp~t~~~~v~~~ktfV~lP~~~nhT~v~--ln~t 316 (1024)
6497 T 6BFU_C 240 FALANLTDTLI-TLTNTTISQITYCDKSVVDSIACQRSSHEVEDGFYSDPKSAVRARQRTIVTLPKLPELEVVQ--LNIS 316 (1024)
6498 T ss_dssp EEEEEEEEEEE-EEETTEEEEEEETTTCHHHHHHHHTTSSSCCSEEEECGGGCBCCSEEEEECSCCCCCEEEEE--EEEE
6499 T ss_pred EEEeeccchhe-eeeCCcccEEEECCCChhcccchhccccccCCCccCCCccccccCCceEEEcCCCCceeEEE--EEEE
6500 Confidence 34444444555 8899999999999977999999999999999999999988764 556899999987765421 1111
6501
6502
6503 Q sp|P0DTC2|SPIK 346 RFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKL 425 (1273)
6504 Q Consensus 346 rfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynykl 425 (1273)
6505 -+...-+ ... +++..|+ -+..|..+ ++ +.+
6506 T Consensus 317 f~n~s~a---g~v----------------~~i~~~~-----~s~yCV~n----s~----------------------ft~ 346 (1024)
6507 T 6BFU_C 317 AHMDFGE---ARL----------------DSVTING-----NTSYCVTK----PY----------------------FRL 346 (1024)
6508 T ss_dssp EEEETTE---EEE----------------EEEEETT-----BSEEECCS----SE----------------------EEE
6509 T ss_pred EeecCCC---Ccc----------------eeEEEec-----cceeEecC----Ce----------------------EEE
6510 Confidence 1110000 000 0011111 11122211 00 111
6511
6512
6513 Q sp|P0DTC2|SPIK 426 PDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERD----------ISTEIYQAGSTPCNGVEGFNCYFPLQSY 495 (1273)
6514 Q Consensus 426 pddftgcviawnsnnldskvggnynylyrlfrksnlkpferd----------isteiyqagstpcngvegfncyfplqsy 495 (1273)
6515 ..+|.. |+.|.+ .+ ..--||..+ ++-.+.+.| |-++....
6516 T Consensus 347 ~~~f~~--------------g~sy~~----~~-~~sCpFr~e~INNyL~FnSlCvSl~~gg-----------Ck~~v~~~ 396 (1024)
6517 T 6BFU_C 347 ETNFMC--------------TGCTMN----LR-TDTCSFDLSAVNNGMSFSQFCLSTESGA-----------CEMKIIVT 396 (1024)
6518 T ss_dssp EEECCE--------------ESSEEE----EE-ESSSSSCHHHHTTTCEEEEEEEESSCCS-----------EEEEEEEE
6519 T ss_pred EEEEee--------------ccCccc----cc-CCCCCCChhhccCCCccCeEEEEeCCCc-----------eeeEEEEE
6520 Confidence 111110 001111 00 011122211 111111222 54444432
6521
6522
6523 Q sp|P0DTC2|SPIK 496 GFQPTNGVGYQPYRVVVLSFE---LLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFGRDIADT 572 (1273)
6524 Q Consensus 496 gfqptngvgyqpyrvvvlsfe---llhapatvcgpkkstnlvknkcvnfnfngltgtgvltesnkkflpfqqfgrdiadt 572 (1273)
6525 . ...|++++.|.++++ ......++|. +..++++.++||++|.-|.+|+|+++++|..+...+.+ .|...-
6526 T Consensus 397 ~-----~~sy~~~~~VyVt~s~Gsri~g~~~~~~-~d~s~i~l~~CvdYnIYG~tG~GvI~~~n~~~~~Gl~~-~s~sG~ 469 (1024)
6527 T 6BFU_C 397 Y-----VWNYLLRQRLYVTAVEGQTHTGTTSVHA-TDTSSVITDVCTDYTIYGVSGTGIIKPSDLLLHNGIAF-TSPTGE 469 (1024)
6528 T ss_dssp S-----SSEEECSCCEEEEEEEEEEEEECSSSSC-CCTTCCCCSSEEEEEETTEEEEEEEEECSCCCCSCSEE-ECTTSC
6529 T ss_pred E-----EeeeeceeEEEEEecCCCeeeccCCccC-CCCCceeeceeeeEEecCeeeeEEEecCCEEeeCcEEE-EcCCCC
6530 Confidence 1 123678888888877 3334445664 56699999999999999999999999999999989988 899999
6531
6532
6533 Q sp|P0DTC2|SPIK 573 TDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRVYSTGSNVFQTRAGCLIG 652 (1273)
6534 Q Consensus 573 tdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrvystgsnvfqtragclig 652 (1273)
6535 .++.+++.++++..|+||....++|+..|.- |+ ++...| +++++.|++..||..+
6536 T Consensus 470 L~~Fk~~~~g~~Y~V~PC~~v~Q~vV~~g~i----VG-~lts~n--------------------~t~s~~f~~~~~~~~~ 524 (1024)
6537 T 6BFU_C 470 LYAFKNITTGKTLQVLPCETPSQLIVINNTV----VG-AITSSN--------------------STENNRFTTTIVTPTF 524 (1024)
6538 T ss_dssp EEEEEETTTTEEEEEECSSCCEEEEEETTEE----EE-EEESCG--------------------GGCCTTCSEEEEETTE
6539 T ss_pred eeEEEeCCCCCEEEEeeCCCCcEEEEECCEE----EE-EEEccC--------------------CCCCccccceeEecee
6540 Confidence 9999999999999999999877765544433 22 122222 3478889999999999
6541
6542
6543 Q sp|P0DTC2|SPIK 653 AEHVNN-SYECDIPIGA----GICASYQTQTNSPRRARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEIL 727 (1273)
6544 Q Consensus 653 aehvnn-syecdipiga----gicasyqtqtnsprrarsvasqsiiaytmslgaensvaysnnsiaiptnftisvtteil 727 (1273)
6545 +.+.++ ..+|+.|+|. |||+.+..-...|+.. + ..-.+...++.|.||+|||++|++|-+
6546 T Consensus 525 ~~~s~~~~~~C~~p~~syg~~giC~dg~~~~~~~~~~----------~-----~p~~~~~vt~~i~IP~nft~~v~~Eyi 589 (1024)
6547 T 6BFU_C 525 FYSTNATTFNCTKPVLSYGPISVCSDGAIVGTSTLQN----------T-----RPSIVSLYDGEVEIPSAFSLSVQTEYL 589 (1024)
6548 T ss_dssp EEEECCSCCCCSCEEEEETTEEEETTSCEEECCCEEC----------C-----CSCSSCCCCSSEEEEEEEEEEEEEEEE
6549 T ss_pred eeecCCCccccccceeeccceeEccCCccccceeeec----------c-----CCceeeccCeEEEccCceEeeEEEeEE
6550 Confidence 999875 7999999999 9999886633322110 0 111123344589999999999999999
6551
6552
6553 Q sp|P0DTC2|SPIK 728 PVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFG-GFNFSQIL 806 (1273)
6554 Q Consensus 728 pvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevfaqvkqiyktppikdfg-gfnfsqil 806 (1273)
6555 ..+|.|.+|||.+|+||++.+|.+||.|||+||..+++||.+.+..+|.+..+++...++-++.+-|..|+ +||||.+|
6556 T Consensus 590 q~~~~kv~idC~~YVC~~~~~C~~ll~qYg~~C~~I~~~l~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~n~s~~l 669 (1024)
6557 T 6BFU_C 590 QVQAEQVIVDCPQYVCNGNSRCLQLLAQYTSACSNIEAALHSSAQLDSREIINMFQTSTQSLQLANITNFKGDYNFSSIL 669 (1024)
6558 T ss_dssp ECCCCEEEECHHHHHHTTBHHHHHHHTTSTTHHHHHHHHHHHHHHHHHHHHHHHTCEEHHHHHHTCGGGGCSSSCCTTTS
6559 T ss_pred eeecCceEEecchhhcCCCHHHHHHHHHhhhHHHHHHHHHHHHHhhhhHHHHHHHhhCcccccccccccCCCCccchhhc
6560 Confidence 99999999999999999999999999999999999999999999999999999999999999998888884 69999999
6561
6562
6563 Q sp|P0DTC2|SPIK 807 PDPSKPSKRSFIEDLLFNKVTLADAGFI-KQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSG 885 (1273)
6564 Q Consensus 807 pdpskpskrsfiedllfnkvtladagfi-kqygdclgdiaardlicaqkfngltvlpplltdemiaqytsallagtitsg 885 (1273)
6565 |.+. +.||+||||||+||..+|.|++ +.|.+|.+....|||+|||.+||+.||||.+++||++.||++|++|....|
6566 T Consensus 670 ~~~~--~~RS~iEDlLF~KV~t~glg~vD~~Y~~C~~g~~i~DL~CaQ~ynGi~VLP~v~~~~~~a~YT~sl~g~m~~gg 747 (1024)
6567 T 6BFU_C 670 TTRI--GGRSAIEDLLFNKVVTSGLGTVDQDYKSCSRDMAIADLVCSQYYNGIMVLPGVVDAEKMAMYTGSLTGAMVFGG 747 (1024)
6568 T ss_dssp CSST--TCCCHHHHHCCCCCCC------CCCGGGGGSTTGGGSHHHHHHTTTEEEECCSSCHHHHHHHHHHHHHGGGCCS
6569 T ss_pred CCCC--CCccHHHHHHcceeeecCCCccchHHHhccCCccHHHHhhccccCeEEEeCCCCCHHHHHHHHHHHHHHHHhhc
6570 Confidence 8774 7999999999999999999999 899999999999999999999999999999999999999999999999999
6571
6572
6573 Q sp|P0DTC2|SPIK 886 WTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSS--------------TASALGKLQDV 951 (1273)
6574 Q Consensus 886 wtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslss--------------tasalgklqdv 951 (1273)
6575 ||. |..||||+||.+|+|++|+||+||.||||+|||.||.|||.||+.+++ +++||.|+|||
6576 T Consensus 748 ~ta----aaaiPFa~~vq~RlN~~~lt~~vL~~NQ~~iA~sFN~A~~~i~~~f~~v~~ai~qts~~~~t~~~Al~kiQ~V 823 (1024)
6577 T 6BFU_C 748 LTA----AAAIPFATAVQARLNYVALQTNVLQENQKILAESFNQAVGNISLALSSVNDAIQQTSEALNTVAIAIKKIQTV 823 (1024)
6578 T ss_dssp SSS----SCCCCHHHHHHHHHHHHTTSSSCCSTTHHHHHHHHHHHHHHHHHHHHTTCCSCCTTCHHHHHHHHHHHHHHHH
6579 T ss_pred HHH----hHhChHHHHHHHHhhhhhhchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6580 Confidence 997 556899999999999999999999999999999999999999988555 99999999999
6581
6582
6583 Q sp|P0DTC2|SPIK 952 VNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSE 1031 (1273)
6584 Q Consensus 952 vnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqtyvtqqliraaeirasanlaatkmse 1031 (1273)
6585 ||++++||++|++||+.|||||||.++||.+|||++||++|+||||+|||.+|.+||+|+|.|++|+|+|+.||..|+.|
6586 T Consensus 824 VN~~~~aL~~l~~qL~~nFgAISssi~dIy~rLd~leAdaQvDRLItGRL~aLna~vtq~l~~~~~v~~sr~lA~qKinE 903 (1024)
6587 T 6BFU_C 824 VNQQGEALSHLTAQLSNNFQAISTSIQDIYNRLEEVEANQQVDRLITGRLAALNAYVTQLLNQMSQIRQSRLLAQQKINE 903 (1024)
6588 T ss_dssp HHTTTHHHHHHHHGGGCCCSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
6589 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6590 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6591
6592
6593 Q sp|P0DTC2|SPIK 1032 CVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG-KAHFPREGVF-VSNGTHWFVTQRNF 1109 (1273)
6594 Q Consensus 1032 cvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg-kahfpregvf-vsngthwfvtqrnf 1109 (1273)
6595 ||..||+|.+|||.|.|++|+||.||.|++|+|.+|+|.+-++.+++|.+|+++ ++..|+.|.+ +.+...|++|.|++
6596 T Consensus 904 CVksQS~R~gFCGnG~Hv~S~~q~AP~Gi~F~H~~~~P~~~~~v~a~~G~C~~~~~~~~~~~g~~~~~~n~~~~~T~r~~ 983 (1024)
6597 T 6BFU_C 904 CVKSQSPRYGFCGNGTHIFSLTQTAPNGIFFMHAVLVPNKFTRVNASAGICVDNTRGYSLQPQLILYQFNNSWRVTPRNM 983 (1024)
6598 T ss_dssp CCCSCCCCTTTSSSSEEEEEEEEEETTEEEEEEEEEEEEEEEEECCBCEEEETTTEEEEECTTEEEEEETTEEEEEESSS
6599 T ss_pred HHhccCCCcCCCCCCeeEEEeeecCCCeEEEEEEEecccceeEEEEEEEEeecCCceEEeCCceEEEeeCCEEEEecccc
6600 Confidence 999999999999999999999999999999999999999999999999999995 7888888866 78778999999999
6601
6602
6603 Q sp|P0DTC2|SPIK 1110 YEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSF 1148 (1273)
6604 Q Consensus 1110 yepqiittdntfvsgncdvvigivnntvydplqpeldsf 1148 (1273)
6605 |||..||..|...-..|||...-+|+++..+..|++-.|
6606 T Consensus 984 y~Pr~~t~~d~v~~~sC~v~y~n~~~~~~~~~~p~~~D~ 1022 (1024)
6607 T 6BFU_C 984 YEPRLPRQADFIQLTDCSVTFYNTTAANLPNIIPDIIDV 1022 (1024)
6608 T ss_dssp CCCBCCCGGGEEEESSCCTTSEEECTTTGGGTSTTCCCT
6609 T ss_pred ccCCCCCcccEEEcccceeEEEECCcccCCCCCCCCCCC
6610 Confidence 999999999999999999999999999999988886544
6611
6612
6613 No 20
6614 >6B3O_B Spike glycoprotein; Coronavirus, membrane fusion, MHV, SARS; 4.1A {Murine coronavirus}
6615 Probab=100.00 E-value=7.3e-117 Score=954.95 Aligned_cols=497 Identities=42% Similarity=0.726 Sum_probs=333.3 Template_Neff=3.300
6616
6617 Q sp|P0DTC2|SPIK 703 NSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVF 782 (1273)
6618 Q Consensus 703 nsvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiaveqdkntqevf 782 (1273)
6619 .....++..|.||+|||++|++|-+.++|.|.+|||.+|+||++.+|.+||.|||+||..+++||.|.+..+|....+++
6620 T Consensus 45 ~~~~~~~~~isIP~nFtlsv~~EyiQt~~~kVsIDC~~YVCngn~rC~~LL~QYgs~C~~I~~aL~~v~~~~d~~~~~~~ 124 (605)
6621 T 6B3O_B 45 VQSVDGLYEMQIPTNFTIGHHEEFIQTRSPKVTIDCAAFVCGDNTACRQQLVEYGSFCVNVNAILNEVNNLLDNMQLQVA 124 (605)
6622 T ss_dssp -CBCSCCCCEEEEEEEEEEEEEEEEECSCCCCCCCHHHHHTCSCHHHHHHHTTSCSHHHHHHHHHHHC------------
6623 T ss_pred CcccCcceEEEecCceEeEEEEEEeeccCCCeEEehhhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6624 Confidence 45778888999999999999999999999999999999999999999999999999999999999999999999999999
6625
6626
6627 Q sp|P0DTC2|SPIK 783 AQVKQIYKTP-----PI-KDFGGFNFSQILPD-----------PSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIA 845 (1273)
6628 Q Consensus 783 aqvkqiyktp-----pi-kdfggfnfsqilpd-----------pskpskrsfiedllfnkvtladagfikqygdclgdia 845 (1273)
6629 ...++.+..+ .| ...|+||||.++|. |++|+.||+|||||||||..+|.|+.+.|..|.+...
6630 T Consensus 125 ~~~~~~~~~s~~~~~~i~~~~g~fN~s~ll~~~~~~~~~~~~~~~~~~~RSaIEDLLFnKVvt~glGt~~dYk~Ct~g~~ 204 (605)
6631 T 6B3O_B 125 SALMQGVTISSRLPDGISGPIDDINFSPLLGCIGSTCAEDGNGPSAIRGRSAIEDLLFDKVKLSDVGFVEAYNNCTGGQE 204 (605)
6632 T ss_dssp --------------------------------------------------------------------------------
6633 T ss_pred HHHhccCcccccCCCCCCCCCCCccchhhcccccCCcccCCCCCCcCCCccHHHHHHCCceEecCCchhHHHHhccCCcc
6634 Confidence 9998888764 22 33456999999986 7778899999999999999999999999999999999
6635
6636
6637 Q sp|P0DTC2|SPIK 846 ARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIAN 925 (1273)
6638 Q Consensus 846 ardlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian 925 (1273)
6639 .|||+|||.|||+.||||..++||++.||++|.+|....|||. |..||||+||.||+||+|+||+||.||||+|||
6640 T Consensus 205 iaDL~CAQyyNGImVLPpVvda~~~amYTaSL~G~ma~gG~Ta----AaaIPFa~~vQaRlNyvaltt~VLq~NQk~iAn 280 (605)
6641 T 6B3O_B 205 VRDLLCVQSFNGIKVLPPVLSESQISGYTTGATAAAMFPPWSA----AAGVPFSLSVQYRINGLGVTMNVLSENQKMIAS 280 (605)
6642 T ss_dssp ----------------------------------------------------------------------------CHHH
6643 T ss_pred hHHHhCccccCcEEeeCCCCCHHHHHHHHHHHHHHhhcccchh----cccCchHHHHHHHhcccccchHHHHHHHHHHHH
6644 Confidence 9999999999999999999999999999999999999999997 556899999999999999999999999999999
6645
6646
6647 Q sp|P0DTC2|SPIK 926 QFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQ 1005 (1273)
6648 Q Consensus 926 qfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslq 1005 (1273)
6649 .||.|+|.||+.++++++||.|+|||||++++||++|++||+.|||||||.++||.+|||++||++|+||||||||.+|.
6650 T Consensus 281 sFN~AignIq~gf~tta~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSI~dIy~RLD~leAdaQVDRLItGRL~aLN 360 (605)
6651 T 6B3O_B 281 AFNNALGAIQDGFDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISASLQEILTRLEAVEAKAQIDRLINGRLTALN 360 (605)
6652 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
6653 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHH
6654 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6655
6656
6657 Q sp|P0DTC2|SPIK 1006 TYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDG 1085 (1273)
6658 Q Consensus 1006 tyvtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdg 1085 (1273)
6659 +||+|+|.+++|+|+|+.||..|+.|||..||+|.+|||.|.|++|+||.||.|++|+|.+|+|.+-++.++.|.+|.++
6660 T Consensus 361 afVtQ~L~~~~eVr~sr~LA~qKINECVKSQS~RygFCGnGtHifSi~q~APnGi~FlH~~y~Pt~~~~V~A~~GlCv~~ 440 (605)
6661 T 6B3O_B 361 AYISKQLSDSTLIKVSAAQAIEKVNECVKSQTTRINFCGNGNHILSLVQNAPYGLYFIHFSYVPISFTTANVSPGLCISG 440 (605)
6662 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHTTTSSCCCCBSCSSSSEEEEEEEEEETTEEEEEEEEEEEEEEEEECCBSCEECSS
6663 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCccCcCCCCeEEEEeeeccCCeEEEEEEEecccceEEEEEEeeEEecC
6664 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999995
6665
6666
6667 Q sp|P0DTC2|SPIK 1086 -KAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDV 1164 (1273)
6668 Q Consensus 1086 -kahfpregvfvsngthwfvtqrnfyepqiittdntfvsgncdvvigivnntvydplqpeldsfkeeldkyfknhtspdv 1164 (1273)
6669 ++..|+.|+|+.+..+|++|.|++|+|..+|..|...-..|||...-++.++..|..|+.-.|++||+++|+|+++.-.
6670 T Consensus 441 ~~~~~~~~g~f~~~n~~~~iT~r~my~Pr~~t~~dfV~itSC~V~Y~Nvt~t~lp~viPdyiDfn~eLee~~~n~t~t~P 520 (605)
6671 T 6B3O_B 441 DRGLAPKAGYFVQDDGEWKFTGSSYYYPEPITDKNSVIMSSCAVNYTKAPEVFLNTSIPNPPDFKEELDKWFKNQTSIAP 520 (605)
6672 T ss_dssp SCEEEESSEEEEEETTEEEEEESSSCCCEECCTTSEEEESCSCCEEEECCCCCCCCCCCCCSCHHHHHTTTCCCCCCCCC
6673 T ss_pred CceEEecCeEEEeeCCeEEEeccccccCCCCCccceEEeeccccEEEecccccCCCCCCCCCChHHHHHHHHhcCCCCCC
6674 Confidence 7999999999999889999999999999999999999999999999999999999999999999999999999987444
6675
6676
6677 Q sp|P0DTC2|SPIK 1165 DLG-DISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
6678 Q Consensus 1165 dlg-disginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
6679 |+. |+.-+|+++.|+..||++|+++.|+||+++|||..-
6680 T Consensus 521 dl~~~ld~fN~T~LNLt~EI~~Lq~~i~~LN~s~IDL~~~ 560 (605)
6681 T 6B3O_B 521 DLSLDFEKLNVTLLDLTYEMNRIQDAIKKLNESYINLIKR 560 (605)
6682 T ss_dssp CCCCCGGGCCCCCCCCHHHHHHHHHHHHHTTTC-------
6683 T ss_pred CcCCCHHHccccccchHHHHHHHHHHHHHHHHHHHHHHHH
6684 Confidence 443 688999999999999999999999999999999754
6685
6686
6687 No 21
6688 >6PZ8_A S protein, G2 heavy chain; MERS-CoV, coronavirus, DPP4, receptor-binding, membrane; HET: MAN, NAG, BMA; 4.19A {Middle East respiratory syndrome-related coronavirus}
6689 Probab=100.00 E-value=8.5e-112 Score=897.44 Aligned_cols=445 Identities=43% Similarity=0.743 Sum_probs=424.4 Template_Neff=3.100
6690
6691 Q sp|P0DTC2|SPIK 694 AYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVE 773 (1273)
6692 Q Consensus 694 aytmslgaensvaysnnsiaiptnftisvtteilpvsmtktsvdctmyicgdstecsnlllqygsfctqlnraltgiave 773 (1273)
6693 .|++.+-. ..+.+++..|.||+||||+|++|.++++|.|.+|||.+|+||++.+|.+||.|||+||..+|++|.|.+.+
6694 T Consensus 12 ~~~~p~~~-~~~~~~~~~i~IP~nFtl~v~~EyiQt~~~kV~IDC~~YVC~~~~~C~~LL~QYgs~C~~I~~aL~~~~~~ 90 (472)
6695 T 6PZ8_A 12 AFNHPIQV-DQLNSSYFKLSIPTNFSFGVTQEYIQTTIQKVTVDCKQYVCNGFQKCEQLLREYGQFCSKINQALHGANLR 90 (472)
6696 T ss_dssp CCCCCEEC-CCCCTTEEEEEECCEEEEEEEEEEEECCCCCEEECHHHHHSSSCHHHHHHHGGGHHHHHHHHHHHHHHHHH
6697 T ss_pred eccCCcee-ccccCCCeeEEeccceEEEEEEEEEEecCCceEEechhhccCCCHHHHHHHHHHHHHHHHHHHHHHHHHhh
6698 Confidence 56666554 67788899999999999999999999999999999999999999999999999999999999999999999
6699
6700
6701 Q sp|P0DTC2|SPIK 774 QDKNTQEVFAQVKQIYKTPPIKDF-GGFNFSQILPDPS---KPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDI--AAR 847 (1273)
6702 Q Consensus 774 qdkntqevfaqvkqiyktppikdf-ggfnfsqilpdps---kpskrsfiedllfnkvtladagfikqygdclgdi--aar 847 (1273)
6703 +|....+++...++-+..|-+..| |+|||+.++|.+. ++++||+||||||+||..+|.|+.+.|..|.... ..|
6704 T Consensus 91 ~d~~~~~~~s~~~~~~~~~~~~~~~g~fN~s~ll~~~~~~~~~~~RS~IEDLLF~KV~t~glG~~~~Yk~Ct~~~g~~i~ 170 (472)
6705 T 6PZ8_A 91 QDDSVRNLFASVKSSQSSPIIPGFGGDFNLTLLEPVSISTGSRSARSAIEDLLFDKVTIADPGYMQGYDDCMQQGPASAR 170 (472)
6706 T ss_dssp HHHHHHHHHHHHCCSEECCCCTTTTTTSCCTTSCCC--------CCCHHHHHHHHHSCCCCCCSSSCGGGGSSSSCTTCC
6707 T ss_pred ccHHHHHHHHhccccccCCCcCCCCCCcccceeccCcCCCCCCcceeHHHHHHcCceeecCCcchHhHHHHHhcCCccHH
6708 Confidence 999999999999999988887777 5799999999775 4458999999999999999999999999999544 899
6709
6710
6711 Q sp|P0DTC2|SPIK 848 DLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQF 927 (1273)
6712 Q Consensus 848 dlicaqkfngltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqf 927 (1273)
6713 ||+|||.|||+.||||.+++||++.||++|.+|....|||+|..+|..||||+||.||+||+|+||+||.||||+|||.|
6714 T Consensus 171 DL~CaQyyNGi~VLPpv~d~~~~a~YTasL~g~ma~gg~T~GitsaaaIPFa~~vq~RlN~v~lt~~VL~~NQk~iA~sF 250 (472)
6715 T 6PZ8_A 171 DLICAQYVAGYKVLPPLMDVNMEAAYTSSLLGSIAGVGWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKLIANKF 250 (472)
6716 T ss_dssp CTTTTHHHHTEEECCCSSHHHHHHHHHHHHHTTCSCSCSSCCSSCBCCCCHHHHHHHHHHTTTCCHHHHHHHHHHHHHHH
6717 T ss_pred HHhcccccCcEEEeCCCCCHHhHHHHHHHHHHHHHhcchhccchhhccCchHHHHHHHhhhhcccHHHHHHHHHHHHHHH
6718 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6719
6720
6721 Q sp|P0DTC2|SPIK 928 NSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTY 1007 (1273)
6722 Q Consensus 928 nsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrlitgrlqslqty 1007 (1273)
6723 |.|||.||+.++++++||.|+|||||++++||++|++||+.|||||||.++||++|||++||++|+||||+|||.+|.+|
6724 T Consensus 251 N~Aig~iq~gf~tt~~AL~KiQ~VVN~q~~aL~~L~~qL~nnFgAISssI~dIy~RLD~leAdaQVDRLItGRL~aLnaf 330 (472)
6725 T 6PZ8_A 251 NQALGAMQTGFTTTNEAFHKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQDAQIDRLINGRLTTLNAF 330 (472)
6726 T ss_dssp HHHHHTHHHHSSTTCHHHHHHHHHHHHHHHHHHHHHHGGGCCSSSSCSCHHHHHHHSCHHHHHHHHHHHHHHHHHHHHHH
6727 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHchHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHH
6728 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6729
6730
6731 Q sp|P0DTC2|SPIK 1008 VTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHD--- 1084 (1273)
6732 Q Consensus 1008 vtqqliraaeirasanlaatkmsecvlgqskrvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichd--- 1084 (1273)
6733 |+|+|.|++|+|+++.||..|+.|||..||+|.+|||.|.|++|+||.||+|++|+|.+|+|.+..+.++.|.+|++
6734 T Consensus 331 Vsq~l~~~~~v~~sr~LA~qKiNECVKSQS~R~gFCGnGtHi~Si~q~APnGi~F~H~~y~Pt~~~~V~a~~GlC~~~~~ 410 (472)
6735 T 6PZ8_A 331 VAQQLVRSESAALSAQLAKDKVNECVKAQSKRSGFCGQGTHIVSFVVNAPNGLYFMHVGYYPSNHIEVVSAYGLCDAANP 410 (472)
6736 T ss_dssp HHHHHHHHHHHHHHHHHHHHHCCCCCSSCCCCSSSSSSSSCEEEEEEEETTEEEEEEEEEEEECCEEEEEESCEEETTEE
6737 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHhcccccCCCCCCeeEEEEeeccCCeEEEEEEEEccCceeEEEEEeEEeecCCC
6738 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999995
6739
6740
6741 Q sp|P0DTC2|SPIK 1085 GKAHFPREGVFVSNG-----THWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDP 1140 (1273)
6742 Q Consensus 1085 gkahfpregvfvsng-----thwfvtqrnfyepqiittdntfvsgncdvvigivnntvydp 1140 (1273)
6743 +++..|+.|+|+.+. ++|++|.|++|+|..||.+|+.. -.|||....+|+++++|
6744 T Consensus 411 ~~~~~p~~g~fv~~n~t~~~~~w~~T~r~~Y~P~~iT~~n~v~-~sc~vny~nv~~~~~~p 470 (472)
6745 T 6PZ8_A 411 TNCIAPVNGYFIKTNNTRIVDEWSYTGSSFYAPEPITSLNTKY-VAPQVTYQNISTNLPPP 470 (472)
6746 T ss_dssp EEEEEESSEEEEECCCTTCCSSEEEEESSSCCCEECCGGGEEE-CCCCTTSEEESSCCCTT
6747 T ss_pred CceEeecCceEEEeCCccccceEEEeccccccCcCCCccceEE-ecCcceEEEccccCCCC
6748 Confidence 578999999999866 46999999999999999999888 78899999999999998
6749
6750
6751 No 22
6752 >6PZ8_F S protein, G2 heavy chain; MERS-CoV, coronavirus, DPP4, receptor-binding, membrane; HET: BMA, MAN, NAG; 4.19A {Middle East respiratory syndrome-related coronavirus}
6753 Probab=100.00 E-value=3.1e-74 Score=636.33 Aligned_cols=621 Identities=20% Similarity=0.314 Sum_probs=345.6 Template_Neff=4.300
6754
6755 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
6756 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
6757 .|... -...-+++.++ -+-.+|+||||..++++..+-.|+||.+.-++.+-.- ++|++. + -.+
6758 T Consensus 12 ~C~~~~~~~~~~~~~~s~~idvs~~~G~yYp~~rvysN~tll~~glfp~~gs~~~~y~---~~~~~~~~~~~~~~~~~~y 88 (726)
6759 T 6PZ8_F 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (726)
6760 T ss_dssp BCCCEEECGGGGCCCCCCCCCGGGTTTCBCCSSCEECSEEEEEEEEECCTTCCCEEEC---CEECCBCSSSBCSEEECSC
6761 T ss_pred ceEEecccccccCCCCCcceecccCceeEeeCCeeEeeeeeeecccccCCCCcceEEE---EeecCCCCCCCccceeecC
6762 Confidence 36655 23334445555 3446899999999999999999999999988876532 333332 2 356
6763
6764
6765 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIR-----------------GWIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
6766 Q Consensus 80 dnpvlpfndgvyfasteksniir-----------------gwifgttldskt---q------sllivnnatnvvi----- 128 (1273)
6767 +.+..||+||+++...+..|.-. .++||+|.+... + +++|+++-.+.++
6768 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~t~~~~~~~~~~~~~~~~ypa~~fGstf~n~s~~~~~~~~~~tlvI~P~~~g~~~~~~~c 168 (726)
6769 T 6PZ8_F 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (726)
6770 T ss_dssp TTCCEECTTCEEEEECTTTTCEEECSSSTTCEEEEECCCCCEEEESCEECCTTSCSCEECSEEEEEEEETTTTEEEEEEE
6771 T ss_pred CCChHHccCeEEEEEeeeeccCCCeeeCCCcccchhhcccceEEeccccCCCCccceeeeceEEEEecCCCCccceeeee
6772 Confidence 77889999999998887666532 256999998766 6 8999999887654
6773
6774
6775 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWME---------SEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
6776 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswme---------sefrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
6777 ...+..-|..|..-+++.-+. .+|-. -+++.|....||+|.|. +.|-+|... ..|- |.|
6778 T Consensus 169 ~~~prt~t~C~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c~~~~~-~nft~d~~~--~wf~----~~F 241 (726)
6779 T 6PZ8_F 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDEIL--EWFG----ITQ 241 (726)
6780 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHEETTEECTTHHHHHHHHHEEEEEEEEEEE-EECCCCCCC--EEEE----EEE
6781 T ss_pred ecccCccccCCCCCeEeeecccCCCCccCCCCcccccccccchhhheecCCcEEEEe-eecCcchhh--heEE----EEE
6782 Confidence 323344555666655542221 23422 36788899999999875 344333211 1111 999
6783
6784
6785 Q sp|P0DTC2|SPIK 195 KNID-GYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
6786 Q Consensus 195 knid-gyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
6787 +..| |.|-+|..++..+. ..-+| |...+.+.. .+-|+..++ .+.+. .-++|||++|
6788 T Consensus 242 ~~~~~G~f~~Y~~d~~~~~~f~f~~~~-~~~~~~yy~---------------vip~~~~~~---~~~~~-~~~~~yV~~L 301 (726)
6789 T 6PZ8_F 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYS---------------IIPHSIRSI---QSDRK-AWAAFYVYKL 301 (726)
6790 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEE---------------ECCEEECCC---GGGCC-EECCEEEEEC
6791 T ss_pred eeCCceeEEEEEEecCCCcceeccccc-ceeccceee---------------eeeeeecCC---cccce-eEEEEEEEEc
6792 Confidence 9999 99999877655442 22233 444444443 333444444 45566 7889999999
6793
6794
6795 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITNLCPFGEVFNATRFASV 350 (1273)
6796 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksftvekgiyqtsnfrvqptesivrfpnitnlcpfgevfnatrfasv 350 (1273)
6797 .+|+|||+|+.||.|++||||+-|+++|-||..+||.+++|+|++|+||+||....+|.++. ..|+|.++++ .++.++
6798 T Consensus 302 ~~~~yLl~Fd~nG~It~AvDCa~d~~sEL~Cst~Sf~p~tGVY~lS~y~aqP~g~V~~~~~~-~~C~~~~~~~-~~~Psp 379 (726)
6799 T 6PZ8_F 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESFDVESGVYSVSSFEAKPSGSVVEQAEG-VECDFSPLLS-GTPPQV 379 (726)
6800 T ss_dssp EEEEEEEEECTTSCEEEEEETTSSHHHHHHHHTSSSSSSCSCEEEEEECCCCEEEEEECCC-------------------
6801 T ss_pred ccceEEEecCCCCeEEEEEeccCCccccceeEeeeecCCCCeeecCcEEEEeeeEEEEecCC-CCCCChHHhc-CCCCCc
6802 Confidence 99999999999999999999999999999999999999999999999999999999999999 9999999999 889999
6803
6804
6805 Q sp|P0DTC2|SPIK 351 YAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFT 430 (1273)
6806 Q Consensus 351 yawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgqtgkiadynyklpddft 430 (1273)
6807 +.|.|+.++||..|+++|++....+.|+||||+|.||.+.||..|++|.|.|..+..++++||++|-|++||||+|++|+
6808 T Consensus 380 ~~w~R~~fsNCnfN~s~Lls~~~~~~f~C~gIspskLa~mCfsSvtiD~Faip~s~~~~L~~g~~g~i~~yNYkld~~~~ 459 (726)
6809 T 6PZ8_F 380 YNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSSAGPISQFNYKQSFSNP 459 (726)
6810 T ss_dssp --------------------------------------------------------------------------------
6811 T ss_pred ceeeEEEEecccccHHHHHhccceeeeeecCCCHHHHhhhccceeeEEEEEcchhhccccCCCCCccchhccccCCCCCC
6812 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999999999
6813
6814
6815 Q sp|P0DTC2|SPIK 431 GCVIAWNSNNLDSK--VGGNYNYLYRLFRKSNLKPFERDISTEIYQAG--STPCN--GVEGFNCYFPLQS---------- 494 (1273)
6816 Q Consensus 431 gcviawnsnnldsk--vggnynylyrlfrksnlkpferdisteiyqag--stpcn--gvegfncyfplqs---------- 494 (1273)
6817 ||+++|+-.+++.. --.+|+|+-|-.+... ++. +++-|-- .+-|+ ... -+|+.+...
6818 T Consensus 460 ~C~l~~~~~~~~~n~t~~~~~~~i~~~~~~~~-----~~~-~~~~~~~~~~~~cpc~~~~-~~~~~~~~~~~~~~~~~~~ 532 (726)
6819 T 6PZ8_F 460 TCLILATVPHNLTTITKPLKYSYINKCSRLLS-----DDR-TEVPQLVNANQYSPCVSIV-PSTVWEDGDYYRKQLSPLE 532 (726)
6820 T ss_dssp --------------------------------------------------------------------------------
6821 T ss_pred ceEEEEEcCcccccCCCcccceeeeeeccCCC-----CCC-cchhhhccccccCCCcccC-CccccCCCCcccccccccc
6822 Confidence 99999985442222 2567777776666443 222 2221100 11111 000 112221111
6823
6824
6825 Q sp|P0DTC2|SPIK 495 -YGFQP----TNGVGYQPYRVVVLSFELLHAPATVCGPK-----KSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQ 564 (1273)
6826 Q Consensus 495 -ygfqp----tngvgyqpyrvvvlsfellhapatvcgpk-----kstnlvknkcvnfnfngltgtgvltesnkkflpfqq 564 (1273)
6827 -+..+ ..++++|.+.+++++++..-.+.|||..+ ..++++.++||++|..|.+|+||++++|..+...+.
6828 T Consensus 533 ~~~~~~~~~~~~~~~~~c~~lvvIt~~~gs~~~TvcP~~~~~~~~~s~i~l~~Cv~YnIYG~tG~GvI~~~n~~~~~gl~ 612 (726)
6829 T 6PZ8_F 533 GGGWLVASGSTVAMTEQLQMGFGITVQYGTDTNSVCPKLEFANDTKIASQLGNCVEYSLYGVSGRGVFQNCTAVGVRQQR 612 (726)
6830 T ss_dssp -------------------------------------------CCSCSCCCSSSEEEEETTEEEEECEEECCCCSCTTSC
6831 T ss_pred CCccccccccceecccceeEEEEEEeecCCCccccccccccccCCceeeeeCeeeeEEeCCceeeEEEEecCeeeeCCEE
6832 Confidence 12222 34889999999999999999999999442 247999999999999999999999999999999999
6833
6834
6835 Q sp|P0DTC2|SPIK 565 FGRDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAIHADQLTPTWRV--YSTGSNV 642 (1273)
6836 Q Consensus 565 fgrdiadttdavrdpqtleilditpcsfggvsvitpgtntsnqvavlyqdvnctevpvaihadqltptwrv--ystgsnv 642 (1273)
6837 +..+.+.-.-++++ .++++..|+||..+.++++..|+ ++.++.||..++|+.+....+..+.+|.||+ +++..+.
6838 T Consensus 613 ~~~s~sg~l~~fk~-~~g~~Y~V~PC~~v~~qvvv~~~--s~~~vgl~ts~nc~~v~~~~~~~~~s~~~~~~~~~~~~~~ 689 (726)
6839 T 6PZ8_F 613 FVYDAYQNLVGYYS-DDGNYYCLRACVSVPVSVIYDKE--TKTHATLFGSVACEHISSTMSQYSRSTRSMLKRRDSTYGP 689 (726)
6840 T ss_dssp EEECTTSCEEEEEC-TTSCEEEECCCCCEEEEEEEETT--TTEEEEECGGGCGGGCCSSCSSCSSSCCHHHHHHHTTSCC
6841 T ss_pred EEecCCCCEEEEEe-CCCCEEEEecCcccceeEEEeCC--CCCEEEEEecccCccccccceeeccCCchhcccccCCCCC
6842 Confidence 97788888999999 99999999999999999999997 7889999999999999999999999999998 8888899
6843
6844
6845 Q sp|P0DTC2|SPIK 643 FQTRAGCLIGAEHVNN-SYECDIPIGAGICASYQT 676 (1273)
6846 Q Consensus 643 fqtragcligaehvnn-syecdipigagicasyqt 676 (1273)
6847 |||-+||++||++.+. ..|||+|+|+|+||.|.+
6848 T Consensus 690 fdT~~GCV~na~n~t~~V~~C~LplG~slC~~~~~ 724 (726)
6849 T 6PZ8_F 690 LQTPVGCVLGLVNSSLFVEDCKLPLGQSLCALPDT 724 (726)
6850 T ss_dssp EECSSCEEETCCEEEEEESCCSSEEETTEEEECCC
6851 T ss_pred CCCchheeeeeecCCCceeeCCCCCCcceecCCCC
6852 Confidence 9999999999999998 999999999999999976
6853
6854
6855 No 23
6856 >7BZ5_A Spike protein S1, Heavy chain; covid-19 antibody, VIRAL PROTEIN, VIRAL; HET: NAG; 1.84A {Severe acute respiratory syndrome coronavirus 2}
6857 Probab=100.00 E-value=3.5e-52 Score=416.50 Aligned_cols=225 Identities=99% Similarity=1.598 Sum_probs=190.3 Template_Neff=4.100
6858
6859 Q sp|P0DTC2|SPIK 319 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 398 (1273)
6860 Q Consensus 319 rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyad 398 (1273)
6861 |+||...++|++++++.|+|.++|+|.++.++|+|.|+.++||..|+++|++..++++|+||||||+||.++||.+|++|
6862 T Consensus 1 raqP~g~V~r~~~~~~~C~~~~~l~~~~~Psp~nW~R~~fsNCnfn~s~Lls~~~~~sf~C~gIspskL~~mCfsSvtiD 80 (229)
6863 T 7BZ5_A 1 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 80 (229)
6864 T ss_dssp ---------------CBCCHHHHHTCSSCCBGGGCEEEEECSEECCCHHHHSCSCCSEEEEESSCSTTCTTCEESEEEEE
6865 T ss_pred CcccceEEEECCCCCCCCChHHHhcCCCCCCchheEEeEEecCCCcHHHHhhcceeceeeEeCCCHHHHcccccCeeEEE
6866 Confidence 78999999999999999999999999999999999999999999999999999999999999999999999999999999
6867
6868
6869 Q sp|P0DTC2|SPIK 399 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGST 478 (1273)
6870 Q Consensus 399 sfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagst 478 (1273)
6871 .|.|+++++++++||++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++|||||++.++|+++.+
6872 T Consensus 81 ~Faip~s~~~~L~~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~~~vt~~~~y~~rr~~~~~~~~f~~~~~~~~y~~~~~ 160 (229)
6873 T 7BZ5_A 81 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGST 160 (229)
6874 T ss_dssp EEEEEGGGGGGSSTTCCSHHHHHTCCCCTTCCEEEEEEECHHHHCCTTCBCCCEEECCCSSCCCTTCCCCCCCCEECSSS
6875 T ss_pred EEEecccceeecCCCCCcHHHhcccCCCCCCCCeEEEEEeCCcccccccchHHHHHhccccCCCccccCCccceeccCCC
6876 Confidence 99999999999999999999999999999999999999999999888899999999999999999999999999999999
6877
6878
6879 Q sp|P0DTC2|SPIK 479 PCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNF 543 (1273)
6880 Q Consensus 479 pcngvegfncyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlvknkcvnfnf 543 (1273)
6881 .|++..+.+|+.|+..|++|++.|+|+|+|+|+|++++...+++|||++|.+|++++++||||..
6882 T Consensus 161 ~c~~~~~~~c~~p~~~~~~~~~~g~g~~c~g~~Vis~k~~~~s~TVC~~~~~T~~v~g~~~~~~~ 225 (229)
6883 T 7BZ5_A 161 PCNGVEGFNCYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFHH 225 (229)
6884 T ss_dssp CCTTCCBTTEECSEEECCBCTTBCGGGSEEEEEEEEEECC-CCCCEECCC---------------
6885 T ss_pred CCCCCCcccceeccCCCCCcccccccccceEEEEEEEEccCCCCccCCCCCCHHHhcCeeecCCC
6886 Confidence 99955599999999999988899999999999999999999999999999999999999999964
6887
6888
6889 No 24
6890 >6YZ5_E Spike glycoprotein, Nanobody H11-D4; nanobody, complex, SARS-Cov-2, VIRAL PROTEIN; HET: NAG, EDO, ACT; 1.8A {Severe acute respiratory syndrome coronavirus 2}
6891 Probab=100.00 E-value=3.5e-51 Score=405.64 Aligned_cols=205 Identities=99% Similarity=1.601 Sum_probs=193.3 Template_Neff=3.900
6892
6893 Q sp|P0DTC2|SPIK 330 PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQ 409 (1273)
6894 Q Consensus 330 pnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrq 409 (1273)
6895 ||+++.|+|.++|+|.++.|+|+|.|+.++||+.|+|+|+++.++++|+||||||+||.++||.+|++|.|.|+++++++
6896 T Consensus 1 ~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfNlS~Lls~~~~~sF~C~gIspskLa~mCfsSVtiD~Faip~s~~~d 80 (210)
6897 T 6YZ5_E 1 PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQ 80 (210)
6898 T ss_dssp ----CBCCHHHHHTCSSCCBGGGCEEEEECSEECCTHHHHTCSSCSEEEEESCCHHHHTTCEESEEEEEEEEEEGGGGGG
6899 T ss_pred CCCcCCCCHHHHhcCCCCCCchheEEeEEecCCCcHHHHhhcceeceeeeeCCCHHHHcccccCeeEEEEEEecccceee
6900 Confidence 78899999999999999999999999999999999999999999999999999999999999999999999999999999
6901
6902
6903 Q sp|P0DTC2|SPIK 410 IAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCY 489 (1273)
6904 Q Consensus 410 iapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncy 489 (1273)
6905 ++||++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++||||+++.++|+++.+.|++..+.||+
6906 T Consensus 81 Lq~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~vnvts~yny~~rr~~~~~~~~f~~~~~~~~y~~~~~~c~~~~~~~c~ 160 (210)
6907 T 6YZ5_E 81 IAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCY 160 (210)
6908 T ss_dssp SSTTCCSHHHHHTCCCCTTCCEEEEEEECHHHHCCTTCBCCCEEECCCSSCCCTTCCCCCCCCEECSSSCCTTCCBTTEE
6909 T ss_pred cCCCCCcHHHhcccCCCCCCCCeEEEEEeCCccccccccHHHHHHhcccCCCCccccccccchhccCCCCCCCCccccce
6910 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999955599999
6911
6912
6913 Q sp|P0DTC2|SPIK 490 FPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLV 534 (1273)
6914 Q Consensus 490 fplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlv 534 (1273)
6915 .|+..|++|.+.|+|+|+|+|+|++++.+++|+||||||+|||.-
6916 T Consensus 161 ~p~~~~~~~~~~g~g~~c~gv~Vis~k~~~~~~t~~~~~~~~~~~ 205 (210)
6917 T 6YZ5_E 161 FPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNKH 205 (210)
6918 T ss_dssp CSEEECCBCTTSCGGGSEEEEEEEEEECCSSCCCEECCCCT----
6919 T ss_pred ecccCCCCCCcccCCccceEEEEEEEEcCCCceEEeCcccccCCC
6920 Confidence 999998988899999999999999999999999999999999853
6921
6922
6923 No 25
6924 >6YLA_E SARS-CoV-2 RBD, Heavy Chain, Light; SARS-CoV-2 Spike protein, RBD, CR3022; HET: DMS, MLI, 1PE, NAG; 2.42A {Severe acute respiratory syndrome coronavirus 2}
6925 Probab=100.00 E-value=3.8e-51 Score=406.04 Aligned_cols=207 Identities=98% Similarity=1.577 Sum_probs=201.0 Template_Neff=3.900
6926
6927 Q sp|P0DTC2|SPIK 328 RFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEV 407 (1273)
6928 Q Consensus 328 rfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdev 407 (1273)
6929 .||++++.|+|.++|||.++.|+|+|.|+.++||+.|+|+|+++.++++|+||||||+||.++||.+|++|.|.|+++++
6930 T Consensus 2 ~~~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfNlS~Lls~~~~~sF~C~gIspskLa~mCfsSVtiD~Faip~s~~ 81 (213)
6931 T 6YLA_E 2 TGPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEV 81 (213)
6932 T ss_pred CCCCCcCCCCHHHHhcCCCCCCchheEEeEEecCCCcHHHHhhcceeceeeeeCCCHHHHcccccCeeEEEEEEecccce
6933 Confidence 47999999999999999999999999999999999999999999999999999999999999999999999999999999
6934
6935
6936 Q sp|P0DTC2|SPIK 408 RQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFN 487 (1273)
6937 Q Consensus 408 rqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfn 487 (1273)
6938 ++++||++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++||||+++.++|+++.+.|++..+.|
6939 T Consensus 82 ~dLq~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~vnvts~yny~~rr~~~~~~~~f~~~~~~~~y~~~~~~c~~~~~~~ 161 (213)
6940 T 6YLA_E 82 RQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFN 161 (213)
6941 T ss_pred eecCCCCCcHHHhcccCCCCCCCCeEEEEEeCCccccccccHHHHHHhcccCCCCccccccccchhccCCCCCCCCcccc
6942 Confidence 99999999999999999999999999999999999999999999999999999999999999999999999999555999
6943
6944
6945 Q sp|P0DTC2|SPIK 488 CYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNLV 534 (1273)
6946 Q Consensus 488 cyfplqsygfqptngvgyqpyrvvvlsfellhapatvcgpkkstnlv 534 (1273)
6947 ||.|+..|++|.+.|+|+|+|+|+|++++.+++|+||||||+|||.-
6948 T Consensus 162 c~~p~~~~~~~~~~g~g~~c~gv~Vis~k~~~~~~t~~~~~~~~~~~ 208 (213)
6949 T 6YLA_E 162 CYFPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGPKKSTNKH 208 (213)
6950 T ss_pred ceecccCCCCCCcccCCccceEEEEEEEEcCCCceEEeCcccccCCC
6951 Confidence 99999998988899999999999999999999999999999999853
6952
6953
6954 No 26
6955 >6ZFO_A SARS-CoV-2 RBD, Nanobody, EY6A heavy; EY6a, RBD, Spike glycoprotein, SARS-CoV-2; HET: NAG;{Severe acute respiratory syndrome coronavirus 2}
6956 Probab=100.00 E-value=2.3e-47 Score=375.21 Aligned_cols=194 Identities=100% Similarity=1.634 Sum_probs=189.3 Template_Neff=4.100
6957
6958 Q sp|P0DTC2|SPIK 333 TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP 412 (1273)
6959 Q Consensus 333 tnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiap 412 (1273)
6960 |+.|+|.++|||.++.++|+|.||.++||+.|+|+|+++.++++|+||||+|+||.++||.+|++|.|.|+++++++++|
6961 T Consensus 1 ~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfn~S~Lls~~~~~sf~C~gIspskL~~mCfsSvtiD~Faip~s~~~~L~~ 80 (194)
6962 T 6ZFO_A 1 TNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAP 80 (194)
6963 T ss_dssp CCBCCCHHHHSCSSCCCSTTCEEEEECSEECCTHHHHHCCCCSEEEEESSCSGGGTTCCBSEEEEEEEEEEHHHHTTSST
6964 T ss_pred CCCCCHHHhhccCCCCCchheEEeEEecCCCcHHHHhhcceeceeeeeCCCHHHHcccccCeeEEEEEEecccceeecCC
6965 Confidence 57899999999999999999999999999999999999999999999999999999999999999999999999999999
6966
6967
6968 Q sp|P0DTC2|SPIK 413 GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL 492 (1273)
6969 Q Consensus 413 gqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncyfpl 492 (1273)
6970 |++|.|++||||||+||+||+|+|+..+++..+.++|||++|.+++++++||||+++.++|+++.+.|++..+.||+.|+
6971 T Consensus 81 G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~~nvt~~y~y~~~~~~~~~~~~f~~~~~~~~y~~~~~~c~~~~~~~c~~p~ 160 (194)
6972 T 6ZFO_A 81 GQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPL 160 (194)
6973 T ss_dssp TCCSHHHHHTCCCCTTCCEEEEEEECTTTSCCTTCBCCCEEECCCSSCCCTTCCCCCCCCEECSSSCCSSCCBTTEECSE
6974 T ss_pred CCCcHHHhcccCCCCCCCCeEEEEEeCCccccccccHHHHHHhcccCCCCccccccccchhccCCCCCCCCccccceecc
6975 Confidence 99999999999999999999999999999999999999999999999999999999999999999999955599999999
6976
6977
6978 Q sp|P0DTC2|SPIK 493 QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCG 526 (1273)
6979 Q Consensus 493 qsygfqptngvgyqpyrvvvlsfellhapatvcg 526 (1273)
6980 ..|++|++.|+|+|+|+|+|++++.+|+|+||||
6981 T Consensus 161 ~~~~~~~~~g~g~~c~g~~Vis~k~~~~~~t~~~ 194 (194)
6982 T 6ZFO_A 161 QSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCG 194 (194)
6983 T ss_dssp EECCBCTTSCTTTSEEEEEEEEEECCSSCCCEEC
6984 T ss_pred cCCCCCCcccCCccceEEEEEEEEcCCCcceecC
6985 Confidence 9989888999999999999999999999999998
6986
6987
6988 No 27
6989 >2GHV_C Spike glycoprotein; SARS, S protein, VIRAL PROTEIN; 2.2A {SARS coronavirus} SCOP: d.318.1.1
6990 Probab=100.00 E-value=3.9e-37 Score=305.00 Aligned_cols=197 Identities=71% Similarity=1.226 Sum_probs=171.8 Template_Neff=4.000
6991
6992 Q sp|P0DTC2|SPIK 330 PNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQ 409 (1273)
6993 Q Consensus 330 pnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrq 409 (1273)
6994 |+++..|+|.++|+|.++.++|+|.|+.++||..|+|+|++..++++|+||||||+||.++||..|++|.|.|..+++++
6995 T Consensus 4 ~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfnls~Lls~~~~~sf~C~gIspskLa~mCfsSvtiD~Faip~s~~~~ 83 (203)
6996 T 2GHV_C 4 PNITNLCPFGEVFNATKFPSVYAWERKKISNCVADYSVLYNSTFFSTFKCYGVSATKLNDLCFSNVYADSFVVKGDDVRQ 83 (203)
6997 T ss_dssp ---CCBCCCHHHHSCSSCCBGGGCEEEEECSSBCCGGGSCSCCBCSEEEEESCBGGGGGGGGCSSEEEEEEEEEGGGGGG
6998 T ss_pred CCccCCCCHHHHhcCCCCCCcceeEEeEEecCCCCHHHHhhccccceeeeeCCCHHHHcccccCeeEEEEEEeccchhhh
6999 Confidence 67789999999999999999999999999999999999999999999999999999999999999999999999999999
7000
7001
7002 Q sp|P0DTC2|SPIK 410 IAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCY 489 (1273)
7003 Q Consensus 410 iapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdisteiyqagstpcngvegfncy 489 (1273)
7004 ++||++|-|++||||||+||+||+++|+-.+++..+.+|||+.++-.|...++|+++|++.-.+-.+..||....-.+|+
7005 T Consensus 84 Lq~G~sG~i~~yNYKlp~~f~gC~l~~~~~~~~vn~t~~~nps~~~~r~~~~~~~~~~~c~c~~~~~~~~c~~~~~~~p~ 163 (203)
7006 T 2GHV_C 84 IAPGQTGVIADYNYKLPDDFMGCVLAWNTRNIDATSTGNYNYKYRYLRHGKLRPFERDISNVPFSPDGKPCTPPALNCYW 163 (203)
7007 T ss_dssp SSTTCCSHHHHHTCCCCTTCCEEEEEEECHHHHCBTTCBCCCEEECCCSSCCCTTCCCCCCCCBCTTSCCCCTTSTTCBC
7008 T ss_pred cCCCCCcHHHhcccCCCCCCcceEEEEEeCccccccCCccCcccchhcccccccCCCccCCCCCCCCCCCCCCCCccccc
7009 Confidence 99999999999999999999999999999888888888788777665555689999999986664444566543333334
7010
7011
7012 Q sp|P0DTC2|SPIK 490 FPLQSYGFQPTNGVGYQPYRVVVLSFELLHAPATVCGP 527 (1273)
7013 Q Consensus 490 fplqsygfqptngvgyqpyrvvvlsfellhapatvcgp 527 (1273)
7014 .|-. +++..+.|+|+|+|+|+|++++.+.+|+||||-
7015 T Consensus 164 ~~~~-~~~~~~~g~g~~c~g~~Vis~k~~~~~~t~~~~ 200 (203)
7016 T 2GHV_C 164 PLND-YGFYTTTGIGYQPYRVVVLSFELLNAPATVSGL 200 (203)
7017 T ss_dssp CEEE-CCBBSSSCGGGSEEEEEEEEECSGGSTCBTTCC
7018 T ss_pred CCCc-CCceecccCCccceEEEEEEEEcCCCceEEeee
7019 Confidence 4322 556677899999999999999999999999994
7020
7021
7022 No 28
7023 >1WYY_A E2 Glycoprotein; membrane fusion, severe acute respiratory; 2.2A {SARS coronavirus} SCOP: h.3.3.1
7024 Probab=100.00 E-value=2.3e-36 Score=288.46 Aligned_cols=99 Identities=89% Similarity=1.142 Sum_probs=83.9 Template_Neff=2.300
7025
7026 Q sp|P0DTC2|SPIK 903 AYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 982 (1273)
7027 Q Consensus 903 ayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndils 982 (1273)
7028 +||+|++|++++||.||||+||+.||.|++.|+..++++++||.|+|||||++++||+.|+.||+.|||||||.++||.+
7029 T Consensus 3 ~~RlNyvalqt~VLq~NQk~iA~sFN~Ai~~i~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSI~dIy~ 82 (149)
7030 T 1WYY_A 3 AYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 82 (149)
7031 T ss_dssp -----CCSCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
7032 T ss_pred ccccchhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHH
7033 Confidence 69999999999999999999999999999999999999999999999999999999999999999999999999999999
7034
7035
7036 Q sp|P0DTC2|SPIK 983 RLDKVEAEVQIDRLITGRL 1001 (1273)
7037 Q Consensus 983 rldkveaevqidrlitgrl 1001 (1273)
7038 |||++||.+|+|||||||+
7039 T Consensus 83 RLD~leAdaQVDRLItGR~ 101 (149)
7040 T 1WYY_A 83 RLDKVEAEVQIDRLITGGR 101 (149)
7041 T ss_dssp HHHHHHHHC----------
7042 T ss_pred HHHHHHHHHHHHHHHhcCC
7043 Confidence 9999999999999999985
7044
7045
7046 No 29
7047 >1WYY_B E2 Glycoprotein; membrane fusion, severe acute respiratory; 2.2A {SARS coronavirus} SCOP: h.3.3.1
7048 Probab=100.00 E-value=2.3e-36 Score=288.46 Aligned_cols=99 Identities=89% Similarity=1.142 Sum_probs=81.9 Template_Neff=2.300
7049
7050 Q sp|P0DTC2|SPIK 903 AYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 982 (1273)
7051 Q Consensus 903 ayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndils 982 (1273)
7052 +||+|++|++++||.||||+||+.||.|++.|+..++++++||.|+|||||++++||+.|+.||+.|||||||.++||.+
7053 T Consensus 3 ~~RlNyvalqt~VLq~NQk~iA~sFN~Ai~~i~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSI~dIy~ 82 (149)
7054 T 1WYY_B 3 AYRFNGIGVTQNVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILS 82 (149)
7055 T ss_dssp -------CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
7056 T ss_pred ccccchhhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHH
7057 Confidence 69999999999999999999999999999999999999999999999999999999999999999999999999999999
7058
7059
7060 Q sp|P0DTC2|SPIK 983 RLDKVEAEVQIDRLITGRL 1001 (1273)
7061 Q Consensus 983 rldkveaevqidrlitgrl 1001 (1273)
7062 |||++||.+|+|||||||+
7063 T Consensus 83 RLD~leAdaQVDRLItGR~ 101 (149)
7064 T 1WYY_B 83 RLDKVEAEVQIDRLITGGR 101 (149)
7065 T ss_dssp HHHHHHHHC----------
7066 T ss_pred HHHHHHHHHHHHHHHhcCC
7067 Confidence 9999999999999999985
7068
7069
7070 No 30
7071 >5X4S_A Spike glycoprotein; SARS-CoV, spike, N-terminal domain, VIRAL; HET: NAG; 2.2A {Human SARS coronavirus}
7072 Probab=100.00 E-value=1.1e-34 Score=297.96 Aligned_cols=261 Identities=56% Similarity=1.068 Sum_probs=238.0 Template_Neff=4.200
7073
7074 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIRGWIFGTT 109 (1273)
7075 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtngtkrfdnpvlpfndgvyfasteksniirgwifgtt 109 (1273)
7076 -|-.+|+||||..+||+..+-.|+||.++-++++-+|. .--.+++++.||+||+++...+++|.-++|+||+|
7077 T Consensus 21 ~s~~~G~yYPd~~~ysN~t~L~qglfp~~gs~~~~~~~-------~~~~y~~~~~~F~dGifv~v~~~~n~t~a~~fGst 93 (285)
7078 T 5X4S_A 21 TSSMRGVYYPDEIFRSDTLYLTQDLFLPFYSNVTGFHT-------INHTFDNPVIPFKDGIYFAATEKSNVVRGWVFGST 93 (285)
7079 T ss_pred cccCceeEecCCeeeecceeeeecccCCCCCCccccCC-------cceecCCCccccCCeEEEEeeeecCCCCceeeeec
7080 Confidence 34568999999999999999999999999999998555 23568899999999999999999999889999999
7081
7082
7083 Q sp|P0DTC2|SPIK 110 LDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNL 189 (1273)
7084 Q Consensus 110 ldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmdlegkqgnfknl 189 (1273)
7085 .+.++++++|+++-+...|.+|.|+.|..|.+.++..-.| --++..|..+.||+|+|.|+.|-+|...+-.+....
7086 T Consensus 94 f~N~s~tviI~p~~~~~~it~C~~~vC~~p~~~~~~~~g~----~~~~~~f~~~~nc~~~~~~~nfT~d~~~~~~~~~~r 169 (285)
7087 T 5X4S_A 94 MNNKSQSVIIINNSTNVVIRACNFELCDNPFFAVSKPMGT----QTHTMIFDNAFNCTFEYISDAFSLDVSEKSGNFKHL 169 (285)
7088 T ss_pred ccCCcEEEEEcCCCCcceEEEeEEEeCCCCeeEEcCCCCc----ccccceeeecCCCeEEEcccccccccCcceeeeeeE
7089 Confidence 9999999999999999999999999999999998874333 567888999999999999999999988888888889
7090
7091
7092 Q sp|P0DTC2|SPIK 190 REFVFKNIDGYFKIYSKHTPINLVRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGY 269 (1273)
7093 Q Consensus 190 refvfknidgyfkiyskhtpinlvrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgy 269 (1273)
7094 ++|+|++.||+|-+|....+.+..+.+|.|+..|.|..-+|..|+||.|...+ |.|-++ .+.|..+.++|||++
7095 T Consensus 170 ~~f~F~~~dG~f~~Y~~~~~~~~f~~~p~~~~~l~yy~vip~s~~~~~~~~~~---~~~~~~---~~~~~~~~~a~yV~~ 243 (285)
7096 T 5X4S_A 170 REFVFKNKDGFLYVYKGYQPIDVVRDLPSGFNTLKPIFKLPLGINITNFRAIL---TAFSPA---QDTWGTSAAAYFVGY 243 (285)
7097 T ss_pred EEEEEEeeCCeEEEEEecCCCcccccCCCccccceeeEeeeeecccccccCCC---CCCCCC---CcccceeeEEEEEEe
7098 Confidence 99999999999999999888887999999999999999999999999997766 777776 678889999999999
7099
7100
7101 Q sp|P0DTC2|SPIK 270 LQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSFT 307 (1273)
7102 Q Consensus 270 lqprtfllkynengtitdavdcaldplsetkctlksft 307 (1273)
7103 |.||+|||+|++||+|++||||+-||++|-||..||-.
7104 T Consensus 244 L~~~t~Ll~fd~nG~It~AvDCa~~~~sELkCs~~~~~ 281 (285)
7105 T 5X4S_A 244 LKPTTFMLKYDENGTITDAVDCSQNPLAELKCSVKSHH 281 (285)
7106 T ss_pred cceeeEEEeecCCCeEeeEEEcccCcchhceeeecCCC
7107 Confidence 99999999999999999999999999999999998753
7108
7109
7110 No 31
7111 >5KWB_A Spike glycoprotein; Coronavirus spike protein, S1-CTD, receptor; HET: NAG, SUC; 1.91A {Human coronavirus HKU1 (isolate N1)}
7112 Probab=99.95 E-value=1.2e-33 Score=297.87 Aligned_cols=271 Identities=23% Similarity=0.387 Sum_probs=226.6 Template_Neff=3.700
7113
7114 Q sp|P0DTC2|SPIK 316 SNFRVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNV 395 (1273)
7115 Q Consensus 316 snfrvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnv 395 (1273)
7116 |+|||||...++|.+.....|+|.++++|.+..+++.|.||.++||..|+|+|++......|+|||++|.||.+.||..|
7117 T Consensus 1 S~y~vqP~g~V~r~~~~~~~C~~~~~l~~~~~Psp~nWeR~~fsNCnfNls~Lls~v~~~sf~C~~i~pskl~~mCfsSv 80 (371)
7118 T 5KWB_A 1 SGFTVKPVATVHRRIPDLPDCDIDKWLNNFNVPSPLNWERKIFSNCNFNLSTLLRLVHTDSFSCNNFDESKIYGSCFKSI 80 (371)
7119 T ss_dssp ----CCCCCSEEECCTTCCBCCHHHHHTCSEEECGGGCEEEEECSEEECHHHHHHHTEEEEEEEESSCGGGTTTCEESEE
7120 T ss_pred CCceeeeeeEEEEeCCCCCCCCHHHHHhCCCCCCccccEEeEEecCCCCHHHHHhhceeceeeeeCCCHHHhcccccCee
7121 Confidence 68999999999999999999999999999999999999999999999999999999999999999999999999999999
7122
7123
7124 Q sp|P0DTC2|SPIK 396 YADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGG----NYNYLYRLFRKSNLKPFERDISTE 471 (1273)
7125 Q Consensus 396 yadsfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvgg----nynylyrlfrksnlkpferdiste 471 (1273)
7126 +.|.|.|..+..+++++|.+|-|++||||+|++|++|+++|+-..++..+.+ +|| |.++..+ |+......
7127 T Consensus 81 tiD~Faip~s~~~dLq~g~sG~i~~~NYKid~~~~sC~l~y~~~~~nvt~t~~nps~~n---~ry~~~~---f~~~~hdv 154 (371)
7128 T 5KWB_A 81 VLDKFAIPNSRRSDLQLGSSGFLQSSNYKIDTTSSSCQLYYSLPAINVTINNYNPSSWN---RRYGFNN---FNLSSHSV 154 (371)
7129 T ss_dssp EEEEEECCGGGGGGGSTTCCSHHHHHTCCCCSSSCEEEEEEEEEGGGCEEECCCCCHHH---HHTTCCC---CCCCTTEE
7130 T ss_pred EEEEEecCcccchhccCCCCcHhHhccccCCCCCCceEEEEEcccceeeecCCCcccch---hhccccC---cCccccce
7131 Confidence 9999999999999999999999999999999999999999997665555443 454 2223222 55555555
7132
7133
7134 Q sp|P0DTC2|SPIK 472 IYQ-----AGSTPCN---------------------------------------------GVEGFNCYFPLQSYGFQPTN 501 (1273)
7135 Q Consensus 472 iyq-----agstpcn---------------------------------------------gvegfncyfplqsygfqptn 501 (1273)
7136 +|. ++.+-|. +..++.|+-+...+.....-
7137 T Consensus 155 vYs~~cf~~~~~yCPC~~p~~~~~c~~~~~~~~~~~~~t~~r~c~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~q~~~~~ 234 (371)
7138 T 5KWB_A 155 VYSRYCFSVNNTFCPCAKPSFASSCKSHKPPSASCPIGTNYRSCESTTVLDHTDWCRCSCLPDPITAYDPRSCSQKKSLV 234 (371)
7139 T ss_dssp EEESCCEECCTTCCCSBCHHHHTTCCBSCCCBCBCCTTCCCCCEEEEEETTEEEEEEESSCSCTTTCSCGGGCSSEECCC
7140 T ss_pred eeeeeeeecCCCccCCCCccccccccCCCCCCCCCCCCccccccccccccccccccccccCCCCCcccCCCCccCceeee
7141 Confidence 554 2222221 11234455454444445567
7142
7143
7144 Q sp|P0DTC2|SPIK 502 GVGYQPYRVVVLSFEL-----------------------------------------LHAPATVCGP---KKSTNLVKNK 537 (1273)
7145 Q Consensus 502 gvgyqpyrvvvlsfel-----------------------------------------lhapatvcgp---kkstnlvknk 537 (1273)
7146 |+|++.+.+.|++.+. .-.++|+|.. +..++++.++
7147 T Consensus 235 gvg~~c~gl~v~~~kcg~~~~~~~~~C~C~~~af~gws~dsc~~~~~c~~f~n~~~~~~~T~t~cP~~~~~~~s~I~l~~ 314 (371)
7148 T 5KWB_A 235 GVGEHCAGFGVDEEKCGVLDGSYNVSCLCSTDAFLGWSYDTCVSNNRCNIFSNFILNGINSGTTCSNDLLQPNTEVFTDV 314 (371)
7149 T ss_dssp CTTCCCCCCCBCGGGBSBTTCCTTSBCCBCGGGBCSEEEEECEETTEEEEEEEEEEESTTCSSEEECSSCCCCCCCCCSS
7150 T ss_pred ccccccceEEEeeeeccCCCCCCCcccccCCCccccccccccccCCceeeccceeccCCCCCCcCCCcccCCCceEEeCe
7151 Confidence 9999999999999998 5668999998 6779999999
7152
7153
7154 Q sp|P0DTC2|SPIK 538 CVNFNFNGLTGTGVLTE-SNKKFLPFQQFGRDIADTTDAVRDPQTLEILDITPCSF 592 (1273)
7155 Q Consensus 538 cvnfnfngltgtgvlte-snkkflpfqqfgrdiadttdavrdpqtleilditpcsf 592 (1273)
7156 ||++|..|.+|+|++++ +++.++..|.+..+.+.-..+++++.++++..|+||..
7157 T Consensus 315 CVdYnIYG~tGqGvItnvT~~~~l~~~gL~yS~sgdl~~fk~~~tg~~Y~V~PC~~ 370 (371)
7158 T 5KWB_A 315 CVDYDLYGITGQGIFKEVSAVYYNSWQNLLYDSNGNIIGFKDFVTNKTYNIFPCYA 370 (371)
7159 T ss_dssp EEEEEETTEEEEEEEEEECGGGCCCSSSEEECTTSCEEEEECTTTCCEEEEECC--
7160 T ss_pred eeeEEeCCCeeeEEEEeccCceeecCCcEEEcCCCCEEEEEcCCCCcEEEEeeccc
7161 Confidence 99999999999999999 99889999999999999999999999999999999975
7162
7163
7164 No 32
7165 >6LXT_F Spike protein S2; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {Severe acute respiratory syndrome coronavirus 2}
7166 Probab=99.90 E-value=2.8e-28 Score=230.50 Aligned_cols=112 Identities=72% Similarity=0.855 Sum_probs=97.2 Template_Neff=2.500
7167
7168 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEA 989 (1273)
7169 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkvea 989 (1273)
7170 |+|++||.||||+||+.||.|++.|++.++++++||.|+|||||++++||+.|++||+.|||||||.++||.+|||++||
7171 T Consensus 1 gltt~VLq~NQk~iAnsFN~AignI~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~~NFgAISSSI~DIy~RLD~leA 80 (132)
7172 T 6LXT_F 1 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVES 80 (132)
7173 T ss_dssp ---CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-
7174 T ss_pred CCchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHc
7175 Confidence 68999999999999999999999999999999999999999999999999999999999999999999999999999999
7176
7177
7178 Q sp|P0DTC2|SPIK 990 EVQID-RLITGRLQSLQTYVTQQLIRAAEIRAS 1021 (1273)
7179 Q Consensus 990 evqid-rlitgrlqslqtyvtqqliraaeiras 1021 (1273)
7180 ..|+| |||||||.+|..||+|.+.+.++...-
7181 T Consensus 81 daQvD~RLItGRLaaLna~v~q~~~~~~~~~~~ 113 (132)
7182 T 6LXT_F 81 GGRGGPDVDLGDISGINASVVNIQKEIDRLNEV 113 (132)
7183 T ss_dssp ---------CCCCTTCCCCCCCCHHHHHHHHHH
7184 T ss_pred cccCCcchhcccHHHHHHHHHHHHHHHHHHHHH
7185 Confidence 99999 799999999999999999998887543
7186
7187
7188 No 33
7189 >6LXT_C 2019-nCoV S2 subunit; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {COVID-19 virus}
7190 Probab=99.90 E-value=2.8e-28 Score=230.50 Aligned_cols=112 Identities=72% Similarity=0.855 Sum_probs=100.9 Template_Neff=2.500
7191
7192 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEA 989 (1273)
7193 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkvea 989 (1273)
7194 |+|++||.||||+||+.||.|++.|++.++++++||.|+|||||++++||+.|++||+.|||||||.++||.+|||++||
7195 T Consensus 1 gltt~VLq~NQk~iAnsFN~AignI~~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~~NFgAISSSI~DIy~RLD~leA 80 (132)
7196 T 6LXT_C 1 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVES 80 (132)
7197 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-
7198 T ss_pred CCchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHc
7199 Confidence 68999999999999999999999999999999999999999999999999999999999999999999999999999999
7200
7201
7202 Q sp|P0DTC2|SPIK 990 EVQID-RLITGRLQSLQTYVTQQLIRAAEIRAS 1021 (1273)
7203 Q Consensus 990 evqid-rlitgrlqslqtyvtqqliraaeiras 1021 (1273)
7204 ..|+| |||||||.+|..||+|.+.+.++...-
7205 T Consensus 81 daQvD~RLItGRLaaLna~v~q~~~~~~~~~~~ 113 (132)
7206 T 6LXT_C 81 GGRGGPDVDLGDISGINASVVNIQKEIDRLNEV 113 (132)
7207 T ss_dssp ------CCCCCCCTTCCCCCCCCHHHHHHHHHH
7208 T ss_pred cccCCcchhcccHHHHHHHHHHHHHHHHHHHHH
7209 Confidence 99999 799999999999999999998887543
7210
7211
7212 No 34
7213 >6C6Z_A Spike protein, CDC2-C2 heavy chain; immune system, antibody, fusion glycoprotein; HET: NAG; 2.1A {Middle East respiratory syndrome-related coronavirus}
7214 Probab=99.85 E-value=6.9e-26 Score=228.84 Aligned_cols=148 Identities=22% Similarity=0.358 Sum_probs=108.8 Template_Neff=3.300
7215
7216 Q sp|P0DTC2|SPIK 319 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 398 (1273)
7217 Q Consensus 319 rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyad 398 (1273)
7218 |+||...++|+++. ..|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||+|.||.++||..|++|
7219 T Consensus 1 rAqP~g~V~r~~~~-~~C~~~~~l~-~~~Psp~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD 78 (231)
7220 T 6C6Z_A 1 EAKPSGSVVEQAEG-VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILD 78 (231)
7221 T ss_dssp ---------------CBCCCHHHHS-BCCCBGGGCEEEEECSSBCCHHHHHTTSEEEEEEEC-----------CCEEEEE
7222 T ss_pred CccceeEEEEecCC-CCCCchHHhc-CCCCCcceeEEEEEecCCccHHHHHhcceeeeeeecCCCHHHHhhhccceeeEE
7223 Confidence 68999999999999 9999999999 999999999999999999999999999999999999999999999999999999
7224
7225
7226 Q sp|P0DTC2|SPIK 399 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRKSNLKPFERDISTEI 472 (1273)
7227 Q Consensus 399 sfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrksnlkpferdistei 472 (1273)
7228 .|.|..++.++++||++|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|. +|..|-++|.
7229 T Consensus 79 ~FaIp~s~~~~Lq~G~sG~i~~yNYKlp~~f~gC~l~y~~~~~~vnvt~p~~y~yia~r~----~~~~~~~~~~ 148 (231)
7230 T 6C6Z_A 79 YFSYPLSMKSDLSVSSAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS----RFLSDDRTEV 148 (231)
7231 T ss_dssp EEECCGGGGGGSSSSCCSHCCCCCCCCCSSSCEEEEEEECCTTCTTBCCCSEEEEEEEEE----EECTTSSCEE
7232 T ss_pred EEecChhhhhhccCCCCCchhhccccCCCCCCceEEEEEcCccccccCCCccceeeeeee----ccCCCCceEE
7233 Confidence 999999999999999999999999999999999999999777666555566666655544 3334445554
7234
7235
7236 No 35
7237 >5XGR_H Spike protein S1; MERS-CoV, BatCoV HKU5, CTD, evolution; HET: NAG; 2.1A {Bat coronavirus HKU5}
7238 Probab=99.85 E-value=9.7e-26 Score=224.72 Aligned_cols=181 Identities=21% Similarity=0.336 Sum_probs=148.3 Template_Neff=4.000
7239
7240 Q sp|P0DTC2|SPIK 335 LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQ 414 (1273)
7241 Q Consensus 335 lcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgq 414 (1273)
7242 .|+|.++++ .++.++|.|.|+.++||..|+++|++..++++|+||||+|.||.+.||..|++|.|.|..+..++++||+
7243 T Consensus 2 ~C~~~~~l~-~~~Psp~nWeR~~fsNCnfNls~Lls~v~v~sF~C~~IspskLa~mCfsSvtiD~Faip~s~~~dLq~G~ 80 (204)
7244 T 5XGR_H 2 ECDFTPMLT-GTPPPIYNFKRLVFTNCNYNLTKLLSLFQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGS 80 (204)
7245 T ss_dssp BCCCGGGGS-BCCCCGGGCEEEEECSEEECHHHHHTTSEEEEEEEESCCHHHHSSCCBSEEEEEEEECCGGGGGGGSTTC
7246 T ss_pred CCCChhHhc-CCCCCccceeEEEEecCCCCHHHHHhhceeeeeEeeCCCHHHhcccccceeEEEEEEecCccchhcCCCC
7247 Confidence 599999999 9999999999999999999999999999999999999999999999999999999999999999999999
7248
7249
7250 Q sp|P0DTC2|SPIK 415 TGKIADYNYKLPDDFTGCVIAWNSNNLDSK--VGGNYNYLYRLFRKSN-----LKPFERDISTEIYQAGSTPCNGVEGFN 487 (1273)
7251 Q Consensus 415 tgkiadynyklpddftgcviawnsnnldsk--vggnynylyrlfrksn-----lkpferdisteiyqagstpcngvegfn 487 (1273)
7252 +|-|++||||+|++|+||+++|+-...+.. --++|+|+-|..+++. +.++++|++. |-... -+
7253 T Consensus 81 sG~i~~yNYKld~s~~sC~l~~~~p~~~vnvt~ps~y~y~~~r~~~~~~~~~~~~~~~~~~cp---------c~~~~-~~ 150 (204)
7254 T 5XGR_H 81 AGAIVQFNYKQDFSNPTCRVLATVPQNLTTITKPSNYAYLTECYKTSAYGKNYLYNAPGAYTP---------CLSLA-SR 150 (204)
7255 T ss_dssp CSHHHHHTCCCCTTSCEEEEEEECCTTCCSBCCCSEEEEEEEEEEECSSSEEECCCCTTCCCT---------THHHH-TT
7256 T ss_pred CchhHhcccCCCCCCCccEEEEEcCchhcccCCccchheeeceeccccccccceeeCCCCccc---------ccccc-cC
7257 Confidence 999999999999999999999995543321 2567777777777665 5555555543 11000 23
7258
7259
7260 Q sp|P0DTC2|SPIK 488 CYF---PLQS----YGFQ--PTNGVGYQPYRVVVLSFELLHAPATVCGPK 528 (1273)
7261 Q Consensus 488 cyf---plqs----ygfq--ptngvgyqpyrvvvlsfellhapatvcgpk 528 (1273)
7262 |+- |+.. +++| ...|+|+| +++|++++....+-|||.-.
7263 T Consensus 151 ~~~~~~~~~~~~~~~~~~~~~~~~~~~~--g~~Vis~k~g~~~~~~~~~~ 198 (204)
7264 T 5XGR_H 151 GFSTKYQSHSDGELTTTGYIYPVTGNLQ--MAFIISVQYGTDTNSVCPMQ 198 (204)
7265 T ss_dssp CCSSTTCEEECSSEEEEEEEEECCSSCE--EEEEEEEECCSCTTSEEECC
7266 T ss_pred CcccCccccCCCcccccCeEeeecCccc--EEEEEEEEeCCCCCcccccc
7267 Confidence 333 3222 4453 24588888 99999999999999999643
7268
7269
7270 No 36
7271 >4QZV_B Dipeptidyl peptidase 4 (E.C.3.4.14.5), Spike; 8-BLADED BETA-PROPELLER DOMAIN, ALPHA/BETA HYDROLASE; HET: NAG, BMA; 2.592A {Homo sapiens}
7272 Probab=99.83 E-value=4.1e-25 Score=224.70 Aligned_cols=137 Identities=24% Similarity=0.439 Sum_probs=111.3 Template_Neff=3.300
7273
7274 Q sp|P0DTC2|SPIK 319 RVQPTESIVRFPNITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYAD 398 (1273)
7275 Q Consensus 319 rvqptesivrfpnitnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyad 398 (1273)
7276 .+||...++|+++. ..|+|.++|+ .++.++|.|.|+.++||..|+++|++...+++|+||||||.||.++||..|++|
7277 T Consensus 1 ~AqP~g~V~r~~~~-~~C~~~~~l~-~~~Psp~nWeR~~fsNCnfN~S~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD 78 (246)
7278 T 4QZV_B 1 EASATGTFIEQPNA-TECDFSPMLT-GVAPQVYNFKRLVFSNCNYNLTKLLSLFAVDEFSCNGISPDSIARGCYSTLTVD 78 (246)
7279 T ss_dssp ---------------CBCCCCTTTS-SCCCCGGGCEEEEECSCBBCHHHHHTTEEEEEEEEESSCTTGGGTCCBSEEEEE
7280 T ss_pred CceeeeEEEEcCCC-CCCCChHHhc-CCCCCcceeEEEEEecCCCcHHHHHhhceeeeeEecCCCHHHHcccccceeeEE
7281 Confidence 37899999999999 9999999999 999999999999999999999999999999999999999999999999999999
7282
7283
7284 Q sp|P0DTC2|SPIK 399 SFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKV--GGNYNYLYRLFRK 458 (1273)
7285 Q Consensus 399 sfvirgdevrqiapgqtgkiadynyklpddftgcviawnsnnldskv--ggnynylyrlfrk 458 (1273)
7286 .|.|..+..++++||++|-|++||||||+||+||+++|+-.+ +..+ -++|+|+.|..++
7287 T Consensus 79 ~FaIp~s~~~~Lq~G~sG~i~~yNYKlp~~f~gC~l~y~~~~-nvn~t~p~~y~yia~r~~~ 139 (246)
7288 T 4QZV_B 79 YFAYPLSMKSYIRPGSAGNIPLYNYKQSFANPTCRVMASVLA-NVTITKPHAYGYISKCSRL 139 (246)
7289 T ss_dssp EEECCGGGGGGGSTTCCCHCCCCCCCCCCSSCEEEEEEEECT-TSCCCCCSEEEEEEEEEEE
7290 T ss_pred EEEcchhhhhhcCCCCCCchhhccccCCCCCCceEEEEEecc-ccccCCcccceeeeeeecC
7291 Confidence 999999999999999999999999999999999999999555 2222 3455555554433
7292
7293
7294 No 37
7295 >4L3N_B S protein; beta-sheet fold, VIRAL PROTEIN; HET: NAG; 2.13A {Human betacoronavirus 2c Jordan-N3/2012}
7296 Probab=99.81 E-value=2.3e-24 Score=216.33 Aligned_cols=124 Identities=20% Similarity=0.356 Sum_probs=116.1 Template_Neff=3.200
7297
7298 Q sp|P0DTC2|SPIK 334 NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPG 413 (1273)
7299 Q Consensus 334 nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapg 413 (1273)
7300 ..|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||||+||.++||..|++|.|.|..+++++++||
7301 T Consensus 3 ~~C~~~~~l~-~~~PsP~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD~FaIp~s~~~~Lq~G 81 (216)
7302 T 4L3N_B 3 VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVS 81 (216)
7303 T ss_dssp CBCCCGGGGS-BCCCCGGGCEEEEECSEEECHHHHHHTSEEEEEEEESSCHHHHTTCCBSEEEEEEEECCGGGHHHHHTG
7304 T ss_pred CCCCchHHhc-CCCCCcceeEEEEEecCCccHHHHHhcceeeeeeecCCCHHHHhhhccceeeEEEEecChhhhhhccCC
7305 Confidence 5799999999 999999999999999999999999999999999999999999999999999999999999999999999
7306
7307
7308 Q sp|P0DTC2|SPIK 414 QTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRK 458 (1273)
7309 Q Consensus 414 qtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrk 458 (1273)
7310 ++|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|.
7311 T Consensus 82 ssG~i~~yNYKlp~df~gC~l~y~~~~~~vnvt~p~~y~yia~r~ 126 (216)
7312 T 4L3N_B 82 SAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS 126 (216)
7313 T ss_dssp GGSHCCCCCCCCCSSSCEEEEEEECCTTCCSBCCCSEEEEEEEEE
7314 T ss_pred CCCchhhccccCCCCCCccEEEEEcCccccccCCCcccceeeeee
7315 Confidence 999999999999999999999999877766666677777666555
7316
7317
7318 No 38
7319 >5YY5_B MERS-CoV RBD, Heavy chain, Light; MERS-CoV, spike glycorptotein, neutralizing antibody; HET: NAG; 2.8A {Middle East respiratory syndrome coronavirus}
7320 Probab=99.81 E-value=3.5e-24 Score=214.39 Aligned_cols=124 Identities=20% Similarity=0.356 Sum_probs=115.2 Template_Neff=3.300
7321
7322 Q sp|P0DTC2|SPIK 334 NLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPG 413 (1273)
7323 Q Consensus 334 nlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapg 413 (1273)
7324 ..|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||+|.||.++||..|++|.|.|..+++++++||
7325 T Consensus 2 ~~C~~~~~l~-~~~Psp~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD~FaIp~s~~~~Lq~G 80 (209)
7326 T 5YY5_B 2 VECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVS 80 (209)
7327 T ss_dssp CBCCCGGGGS-BCCCBGGGCEEEEECSEEECHHHHHHTSEEEEEEEESSCHHHHTTCCBSEEEEEEEECCGGGGGGSSTT
7328 T ss_pred CCCCchHHhc-CCCCCcceeEEEEEecCCccHHHHHhcceeeeeeecCCCHHHHhhhccceeeEEEEecChhhhhhccCC
7329 Confidence 4799999999 999999999999999999999999999999999999999999999999999999999999999999999
7330
7331
7332 Q sp|P0DTC2|SPIK 414 QTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRK 458 (1273)
7333 Q Consensus 414 qtgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrk 458 (1273)
7334 ++|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|.
7335 T Consensus 81 ~sG~i~~yNYKlp~~f~gC~l~y~~~~~~vnvt~p~~y~yia~r~ 125 (209)
7336 T 5YY5_B 81 SAGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS 125 (209)
7337 T ss_dssp CCSHCCCCCCCCCSSSCEEEEEEECCTTCTTBCCCSCEEEEEEEE
7338 T ss_pred CCCchhhccccCCCCCCccEEEEEcCccccccCCCcccceeeeee
7339 Confidence 999999999999999999999999777666655666666665554
7340
7341
7342 No 39
7343 >4L72_B Dipeptidyl peptidase 4 (E.C.3.4.14.5), MERS-CoV; alpha/beta hydrolase beta-propeller, Glycolation, virus; HET: BMA, NAG; 3.005A {Homo sapiens}
7344 Probab=99.81 E-value=4e-24 Score=213.42 Aligned_cols=123 Identities=20% Similarity=0.365 Sum_probs=115.1 Template_Neff=3.300
7345
7346 Q sp|P0DTC2|SPIK 335 LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIAPGQ 414 (1273)
7347 Q Consensus 335 lcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqiapgq 414 (1273)
7348 .|+|.++++ .++.++|.|.|+.++||..|+++|++...+++|+||||+|+||.++||..|++|.|.|..+++++++||+
7349 T Consensus 1 ~C~~~~~~~-~~~Psp~nWeR~~fsNCnfNlS~Lls~v~v~sF~C~gIsPskLa~mCfsSVtiD~FaIp~s~~~~Lq~G~ 79 (204)
7350 T 4L72_B 1 ECDFSPLLS-GTPPQVYNFKRLVFTNCNYNLTKLLSLFSVNDFTCSQISPAAIASNCYSSLILDYFSYPLSMKSDLSVSS 79 (204)
7351 T ss_pred CCChhHHhh-cCCCCcceeEEEEEecCCCCHHHHHhhceeeeeEeeCCCHHHHcccccCeeeEEEEeccccchhhcCCCC
7352 Confidence 489999999 9999999999999999999999999999999999999999999999999999999999999999999999
7353
7354
7355 Q sp|P0DTC2|SPIK 415 TGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYNYLYRLFRK 458 (1273)
7356 Q Consensus 415 tgkiadynyklpddftgcviawnsnnldskvggnynylyrlfrk 458 (1273)
7357 +|-|++||||+|+||+||+++|+-.+++..+.++.+|-|+..|.
7358 T Consensus 80 sG~i~~yNYKlp~~f~gC~l~y~~~~~~vnvt~p~~y~yia~r~ 123 (204)
7359 T 4L72_B 80 AGPISQFNYKQSFSNPTCLILATVPHNLTTITKPLKYSYINKCS 123 (204)
7360 T ss_pred CchHHhccccCCCCCCceEEEEEcCcccccCCCccccceeeeec
7361 Confidence 99999999999999999999999877666666677777666555
7362
7363
7364 No 40
7365 >3R4D_D CEA-related cell adhesion molecule 1; immunoglobulin, beta-sandwich, mCEACAM1a - immunoglobulin; HET: NAG; 3.1A {Mus musculus}
7366 Probab=99.80 E-value=5.2e-24 Score=219.92 Aligned_cols=240 Identities=20% Similarity=0.268 Sum_probs=141.9 Template_Neff=4.700
7367
7368 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNI------ 100 (1273)
7369 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksni------ 100 (1273)
7370 -|-.+|+||||..++|++.+-.|+||.++-++.+-.-. +|++- --.+++++.||+||+++...+++|.
7371 T Consensus 30 vs~~~G~yYp~~rvysN~t~L~qglfp~~gs~~~~y~~---t~~~~~~~~~~y~~~~~~F~dGifv~v~~~~n~~~~~~~ 106 (288)
7372 T 3R4D_D 30 VSQGLGTYYVLDRVYLNATLLLTGYYPVDGSKFRNLAL---TGTNSVSLSWFQPPYLSQFNDGIFAKVQNLKTSTPSGAT 106 (288)
7373 T ss_dssp ---------------------CEEECCCTTCCCEECCC---EESSEEEGGGSSTTTSEECTTEEEEEEECGGGGSCTTCC
7374 T ss_pred eecCeEEEEeCCeEEeceeeeecccccCCCCceEEEEe---ecCCCCccceecCCcchhcCCeEEEEeeecccCCCCccc
7375 Confidence 45578999999999999999999999999988875422 34332 2467888999999999999998875
7376
7377
7378 Q sp|P0DTC2|SPIK 101 --IRGWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEYVSQPFLMD 178 (1273)
7379 Q Consensus 101 --irgwifgttldsktqsllivnnatnvvikvcefqfcndpflgvyyhknnkswmesefrvyssannctfeyvsqpflmd 178 (1273)
7380 -..++||+|.+..+++++|+++-+...|.+|.|+.|..|.+.++..-+|.+.. +++. ..+.||+|.+. +.|-+|
7381 T Consensus 107 ~~ypa~~fGstf~n~s~tvvI~P~~~~~~it~C~~~vC~~p~~~~~p~~g~~~~~--~~~~-~~~~~c~~~~~-~nfT~d 182 (288)
7382 T 3R4D_D 107 AYFPTIVIGSLFGYTSYTVVIEPYNGVIMASVCQYTICQLPYTDCKPNTNGNKLI--GFWH-TDVKPPICVLK-RNFTLN 182 (288)
7383 T ss_dssp CCSCCEEEESSCSSSSEEEEEEEETTEEEEEEEECCBBSSCCEESSCCCTTCTTC--CSSB-CCSSCCCEEEE-EEEECC
7384 T ss_pred eecceEEEecccCCcceEEEEeCCCceEEEEEEEEEEcCCCeeEEccCCCCCcee--eeee-ecCCCCEEEEe-eeeccC
7385 Confidence 46788999999999999999999999999999999999999888744332222 3445 67889999764 445444
7386
7387
7388 Q sp|P0DTC2|SPIK 179 LEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSS 255 (1273)
7389 Q Consensus 179 legkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdss 255 (1273)
7390 ...+ .|. |+|++.||.|-+|-.+...+. .+.+| |+..+.+. .+-|+..++ +
7391 T Consensus 183 ~~~~--~~~----f~F~~~~G~f~~Y~~~~~~~~~f~f~~~~-g~~~~~yy----------------vip~~~~~~---~ 236 (288)
7392 T 3R4D_D 183 VNAD--AFY----FHFYQHGGTFYAYYADKPSATTFLFSVYI-GDILTQYY----------------VLPFICNPT---A 236 (288)
7393 T ss_dssp TTCS--EEE----EEEEEETTEEEEEEESSSSCCEEEEEEEC-SSCCCEEE----------------ECCEECCCS---S
7394 T ss_pred cChh--eee----EEEEEcCCEEEEEEECCCCCceeeeccee-ccccceeE----------------EeeeeecCC---C
7395 Confidence 3321 122 999999999988877766553 55555 66555555 334444444 4
7396
7397
7398 Q sp|P0DTC2|SPIK 256 SGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLK 304 (1273)
7399 Q Consensus 256 sgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlk 304 (1273)
7400 ++| ..++|||++|.+|+|||+|++||.|++||||+-|+++|-||...
7401 T Consensus 237 ~~~--~~~~~yV~~L~~r~yLl~Fd~nG~It~AvDCa~~~~sEL~~~~~ 283 (288)
7402 T 3R4D_D 237 GST--FAPRYWVTPLVKRQYLFNFNQKGVITSAVDCASSYTSEIKCKTH 283 (288)
7403 T ss_dssp CSC--CCCCEEEEECCEEEC-----------------------------
7404 T ss_pred CCc--cccEEEEEeceeeeEEEeecCCCeEeEEEEcccCcccccccccC
7405 Confidence 455 78899999999999999999999999999999999999999743
7406
7407
7408 No 41
7409 >4NJL_A S protein; six-helix-bundle, coronavirus, MERS-Cov, fusion inhibitor; HET: PGE; 2.3A {Middle East respiratory syndrome coronavirus}
7410 Probab=99.79 E-value=1.2e-23 Score=199.38 Aligned_cols=122 Identities=42% Similarity=0.571 Sum_probs=111.0 Template_Neff=2.500
7411
7412 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEA 989 (1273)
7413 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkvea 989 (1273)
7414 |+||+||.||||+||+.||.|+|.|++.+.++++||.|+|||||++++||+.|+.||+.|||||||.++||.+|||++||
7415 T Consensus 2 gltq~VLq~NQk~iA~sFN~AignIq~gf~tts~AL~KIQdVVN~q~~aL~~Lt~QL~nNFgAISSSIqdIy~RLD~LeA 81 (131)
7416 T 4NJL_A 2 GITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLEQ 81 (131)
7417 T ss_dssp -CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
7418 T ss_pred CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHHh
7419 Confidence 78999999999999999999999999999999999999999999999999999999999999999999999999999999
7420
7421
7422 Q sp|P0DTC2|SPIK 990 EVQIDRLI--TGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLG 1035 (1273)
7423 Q Consensus 990 evqidrli--tgrlqslqtyvtqqliraaeirasanlaatkmsecvlg 1035 (1273)
7424 .+|++|+| .||++-+.+ +|....-+..|+.-+..|..||...
7425 T Consensus 82 Daqrl~~l~~~~~~~~~n~----~l~d~t~~~~s~~q~~~~~ne~~~~ 125 (131)
7426 T 4NJL_A 82 SGGRGGSIPNFGSLTQINT----TLLDLTYEMLSLQQVVKALNESYID 125 (131)
7427 T ss_dssp SSSCSCCCCCCCCCCCCCC----CCCCCHHHHHHHHHHHHHHHTTCCC
7428 T ss_pred HhcccchhhhhhhHHHHhH----hHHHHHHHHhhHHHHHHHHHHhccc
7429 Confidence 99999988 888776665 6666666777887788888888653
7430
7431
7432 No 42
7433 >6QFY_A Spike glycoprotein; sialic acid binding, beta-sandwich, viral; HET: NAG, BMA; 2.97A {Porcine hemagglutinating encephalomyelitis virus}
7434 Probab=99.78 E-value=2.6e-23 Score=214.69 Aligned_cols=236 Identities=20% Similarity=0.276 Sum_probs=176.2 Template_Neff=4.800
7435
7436 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNII----- 101 (1273)
7437 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksnii----- 101 (1273)
7438 -|-.+|+||||..++|+..+-.|+||.++-++.+-.-. +|++- --.+++++.||+||+++...+++|.-
7439 T Consensus 29 vs~~~G~yYp~~r~ysN~t~L~qglfp~~gs~~~~y~~---t~~~~~~~~~~y~~~~~~F~dGifv~v~~~~n~~~~~~~ 105 (288)
7440 T 6QFY_A 29 VTNGLGTFYVLDRVYLNTTLLLNGYYPISGATFRNMAL---KGTRLLSTLWFKSPFLSPFNDGIFAKVKNSRFSKDGVIY 105 (288)
7441 T ss_dssp CTTSTTCBCCTTCCCCSEEEEEEEEEECTTCEEEECCC---EESSCEEGGGGSTTTSEECSSEEEEEEECBCCEETTEEC
7442 T ss_pred cccCceeEecCCceeccceeeeeceecCCCCCceeeee---ecCCCCCcceecCCCcccccCcEEEEeEEeecCCCCCce
7443 Confidence 45568999999999999999999999999888875422 33332 34678889999999999999988863
7444
7445
7446 Q sp|P0DTC2|SPIK 102 ---RGWIFGTTLDSKTQSLLIVNNATNV-----V---IKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEY 170 (1273)
7447 Q Consensus 102 ---rgwifgttldsktqsllivnnatnv-----v---ikvcefqfcndpflgvyyhknnkswmesefrvyssannctfey 170 (1273)
7448 -.++||+|.+..+++++|+++-+++ . |.+|.|+.|..|...++..-.| + --+++. ..+.+|+|.+
7449 T Consensus 106 ~~yp~~~fGstf~n~s~tvvI~P~~~g~~~~~~~~~~it~C~~~vC~~p~~~~~p~~g~-~--~~~~~~-~~~~~c~~~~ 181 (288)
7450 T 6QFY_A 106 SEFPAITIGSTFVNSSHSIVVKPHTSFINGNLQGLLQISVCQYTMCEYPHTICHPNLGN-Q--RIELWH-YDTDVVSCLY 181 (288)
7451 T ss_dssp CBCCCEEEESSCSTTSCEEEEEEEE----EEEEEEEEEEEECCCEEEEEEEECCGGGCC-S--SCCEEE-CC----CSEE
7452 T ss_pred eecCceeeeccccCCceEEEEcCCCCCeeccccccceeeeeeEEecCCCeeEEcCCCCC-c--cceeeE-EecCCceEEE
7453 Confidence 3677999999999999999998864 3 6799999999999988874443 3 234555 7789999976
7454
7455
7456 Q sp|P0DTC2|SPIK 171 VSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRS 247 (1273)
7457 Q Consensus 171 vsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrs 247 (1273)
7458 . +.|-+|...+ .|. |+|++.||.|-+|-.+...+. .+.+| |+..+.+. -+|..++
7459 T Consensus 182 ~-~nfT~d~~~~--~~~----f~F~~~~G~f~~Y~~~~~~~~~f~f~~~~-~~~~~~yy-vip~~~~------------- 239 (288)
7460 T 6QFY_A 182 K-RNFTYDVNAD--YLY----FHFYQEGGTFYAYFTDTGFVTKFLFKLYL-GTVLSHYY-VMPLTCD------------- 239 (288)
7461 T ss_dssp E-ECCBCCTTCS--EEE----EEEEEETTEEEEEEESSSSSBEEEEEEEC-SSCCCEEE-ECCEECS-------------
7462 T ss_pred e-eeeccccccc--eEE----EEEEEcCCeEEEEEeccCCcceeeecCCc-ccccceeE-EceecCC-------------
7463 Confidence 4 4554444332 222 999999999988877766553 55566 66666665 2232222
7464
7465
7466 Q sp|P0DTC2|SPIK 248 YLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLKS 305 (1273)
7467 Q Consensus 248 yltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlks 305 (1273)
7468 ++ ..++|||++|.+|+|||+|++||.|++||||+-|+++|-||..+|
7469 T Consensus 240 --~~---------~~~~~yV~~L~~~~yLl~Fd~nG~It~AvDCa~~~~sEL~Cst~S 286 (288)
7470 T 6QFY_A 240 --SA---------LSLEYWVTPLTTRQFLLAFDQDGVLYHAVDCASDFMSEIMCKTSS 286 (288)
7471 T ss_dssp --S-------------CEEEEEEEEEEEEEEECTTCCEEEEEETTSCHHHHHHHHCCS
7472 T ss_pred --Cc---------cceeEEEEEcceeeEEEeecCCCeEeeEEEcccCcchhhccccCC
7473 Confidence 22 668999999999999999999999999999999999999998776
7474
7475
7476 No 43
7477 >4H14_A Spike glycoprotein; beta-sandwich, sugar binding, VIRAL PROTEIN; HET: NAG; 1.55A {Bovine coronavirus}
7478 Probab=99.78 E-value=3.5e-23 Score=214.01 Aligned_cols=235 Identities=21% Similarity=0.266 Sum_probs=184.1 Template_Neff=4.700
7479
7480 Q sp|P0DTC2|SPIK 30 NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG---TKRFDNPVLPFNDGVYFASTEKSNI------ 100 (1273)
7481 Q Consensus 30 nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng---tkrfdnpvlpfndgvyfasteksni------ 100 (1273)
7482 -|-.+|+||||..++|+..+-.|+||.++-++.+-.-. +|++- --.+++++.||+||+++...+++|.
7483 T Consensus 29 vs~~~G~yYp~~rvysN~t~L~qglfp~~gs~~~~y~~---t~~~~~~~~~~y~~~~~~F~dGifv~v~~~~n~~~~~~~ 105 (290)
7484 T 4H14_A 29 VTNGLGTYYVLDRVYLNTTLLLNGYYPTSGSTYRNMAL---KGTLLLSRLWFKPPFLSDFINGIFAKVKNTKVIKKGVMY 105 (290)
7485 T ss_dssp CTTSTTCBCCTTCCCCSEEEEEEEEECCTTCCCEECCC---EESSCEEGGGGSTTTSEECSSEEEEEEECEEEEETTEEE
7486 T ss_pred cccCeeEEEeCCeEEeeeeeeecceecCCCCceeeeee---eeccccccccccCCccccccCcEEEEEEeecccCCCcee
7487 Confidence 45578999999999999999999999999988875422 34332 2467888999999999999998875
7488
7489
7490 Q sp|P0DTC2|SPIK 101 --IRGWIFGTTLDSKTQSLLIVNNATNV-----V---IKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVYSSANNCTFEY 170 (1273)
7491 Q Consensus 101 --irgwifgttldsktqsllivnnatnv-----v---ikvcefqfcndpflgvyyhknnkswmesefrvyssannctfey 170 (1273)
7492 -..++||+|.+..+++++|+++-+++ . |.+|.|+.|..|.+.++..-.| + --+++. ..+.||+|.|
7493 T Consensus 106 ~~ypa~~fGstf~n~s~tvvI~P~~~g~~~~~~~~~~it~C~~~vC~~p~~~~~p~~g~-~--~~~~~~-~~~~~c~~~~ 181 (290)
7494 T 4H14_A 106 SEFPAITIGSTFVNTSYSVVVQPHTTNLDNKLQGLLEISVCQYTMCEYPHTICHPKLGN-K--RVELWH-WDTGVVSCLY 181 (290)
7495 T ss_dssp EECCCEEEESSCSTTSCEEEEEEEEEESSSSEEEEEEEEEECCCEEEEEEEECCGGGCC-S--SCCEEE-CCCSCCCEEE
7496 T ss_pred eecCeeEEeccccCCeeEEEEcCCCCCccchhcceeEeeeeeEEecCCCeEEEeccCCC-c--eeeeeE-EecCCceEEE
7497 Confidence 46788999999999999999998864 3 6799999999999988874443 3 234455 7789999976
7498
7499
7500 Q sp|P0DTC2|SPIK 171 VSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRS 247 (1273)
7501 Q Consensus 171 vsqpflmdlegkqgnfknlrefvfknidgyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrs 247 (1273)
7502 . +.|-+|...+ .|. |+|++.||.|-+|-.+...+. .+.+| |+..+.+. -+|..++.
7503 T Consensus 182 ~-~nfT~d~~~~--~~~----f~F~~~~G~f~~Y~~~~~~~~~f~f~~~~-~~~~~~yy-vip~~~~~------------ 240 (290)
7504 T 4H14_A 182 K-RNFTYDVNAD--YLY----FHFYQEGGTFYAYFTDTGVVTKFLFNVYL-GTVLSHYY-VLPLTCSS------------ 240 (290)
7505 T ss_dssp E-EEEECCTTCS--EEE----EEEEEETTEEEEEEESSSSSBEEEEEEEC-SSCCCEEE-ECCEECSS------------
7506 T ss_pred e-eeeccccccc--eee----EEEEEeCCeEEEEEEccCcccceEeccee-eeecceeE-EceeecCC------------
7507 Confidence 4 4554544332 222 999999999988877766553 55566 66666665 23333332
7508
7509
7510 Q sp|P0DTC2|SPIK 248 YLTPGDSSSGWTAGAAAYYVGYLQPRTFLLKYNENGTITDAVDCALDPLSETKCTLK 304 (1273)
7511 Q Consensus 248 yltpgdsssgwtagaaayyvgylqprtfllkynengtitdavdcaldplsetkctlk 304 (1273)
7512 + ..++|||++|.+|+|||+|++||.|++||||+-|+++|-||...
7513 T Consensus 241 ---~---------~~~~~yV~~L~~r~yLl~Fd~nG~It~AvDCa~~~~sEL~c~~~ 285 (290)
7514 T 4H14_A 241 ---A---------MTLEYWVTPLTSKQYLLAFNQDGVIFNAVDCKSDFMSEIKCKTH 285 (290)
7515 T ss_dssp ---C---------CCCCEEEEEEEEEEEEEEECTTSCEEEEEETTSSHHHHHHHHSC
7516 T ss_pred ---c---------cceeEEEEeceeeeEEEEecCCCeEeEEEecccCcchhhhcccC
7517 Confidence 1 66899999999999999999999999999999999999999753
7518
7519
7520 No 44
7521 >4MOD_B HR1 of S protein, LINKER; MERS-CoV, Viral envelope proteins, Spike; 1.901A {Human betacoronavirus 2c EMC/2012}
7522 Probab=99.75 E-value=1.9e-22 Score=191.27 Aligned_cols=118 Identities=35% Similarity=0.489 Sum_probs=66.4 Template_Neff=3.100
7523
7524 Q sp|P0DTC2|SPIK 918 ENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKV--EAEVQIDR 995 (1273)
7525 Q Consensus 918 enqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkv--eaevqidr 995 (1273)
7526 ||||+||+.||.|+|.|++.+.++++||.|+|||||+++++|+.|.+||..|||+|||.++||..|||++ ||.+|+||
7527 T Consensus 2 ~NQk~iA~sFN~A~~~i~~~~~t~~~Al~kiQ~VVN~q~~aL~~l~~EL~knFkAISSsI~dIy~rld~~~~~ad~qvdr 81 (129)
7528 T 4MOD_B 2 ENQKLIANKFNQALGAMQTGFTTTNEAFQKVQDAVNNNAQALSKLASELSNTFGAISASIGDILVPRGSGGSGGSGGLEV 81 (129)
7529 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC--------------------------------
7530 T ss_pred hHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhCcchhhHHHhhhccCCCCCCccccchh
7531 Confidence 7999999999999999999999999999999999999999999999999999999999999999999997 89999999
7532
7533
7534 Q sp|P0DTC2|SPIK 996 LITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKR 1039 (1273)
7535 Q Consensus 996 litgrlqslqtyvtqqliraaeirasanlaatkmsecvlgqskr 1039 (1273)
7536 ||+|||.+|.++++.--...++++ -...+.-||+..+.+-
7537 T Consensus 82 LitgrL~~LNa~~~dl~~em~~l~----~vvk~LNes~idlkel 121 (129)
7538 T 4MOD_B 82 LFQGPLTQINTTLLDLTYEMLSLQ----QVVKALNESYIDLKEL 121 (129)
7539 T ss_dssp -------CCCCCCCCCHHHHHHHH----HHHHHHHTTCCC----
7540 T ss_pred hcCCChHHHHHHHHHHHHHHHHHH----HHHHHHHHHhhcHHHH
7541 Confidence 999999999999876544333333 3667788888766543
7542
7543
7544 No 45
7545 >5X4R_A S protein; MERS-CoV, spike, N-terminal domain, VIRAL; HET: NAG; 1.5A {Middle East respiratory syndrome coronavirus}
7546 Probab=99.71 E-value=2.2e-21 Score=204.51 Aligned_cols=263 Identities=21% Similarity=0.314 Sum_probs=191.1 Template_Neff=4.200
7547
7548 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
7549 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
7550 .|... ....-+++.++ -+-.+|+||||..++++..+-.|+||.+.-++.+-.- ++|++. + -.+
7551 T Consensus 12 ~C~~~~~~~~~~~~~~~~~idvs~~~G~yYp~~rvysN~tlL~qglfp~~gs~~~~y~---~~~~~~~~~~~~~~~~~~y 88 (342)
7552 T 5X4R_A 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (342)
7553 T ss_dssp BCCCEEECGGGGCCCCCCCCCGGGTTTCBCCTTSCCCSEEEEEEEEECCTTCCCEEEC---CEECCBCSSCBCSEEECSG
7554 T ss_pred ceEEeccCccccCCCCCcceecccCceeEeeCCeeEeeeeeeeeccccCCCCcceEEE---EEecCCCCCCCcceeeecC
7555 Confidence 36665 23333444555 3446899999999999999999999999988887543 333333 2 356
7556
7557
7558 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIRG-----------------WIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
7559 Q Consensus 80 dnpvlpfndgvyfasteksniirg-----------------wifgttldskt---q------sllivnnatnvvi----- 128 (1273)
7560 +.+..||+||+++...+++|.-.+ ++||+|.+... + +++|+++-++.++
7561 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~t~~~~~~~~~~~~~~~~ypa~~fGstF~N~s~~~~~~~~~~tlvI~P~~~g~~~~~~~c 168 (342)
7562 T 5X4R_A 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (342)
7563 T ss_dssp GGCCEECTTCEEEEESTTTTSEEECSSSTTCEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEE
7564 T ss_pred CCChhhccCeEEEEEeeeeccCCCeeecCccccchhhcccceEEecccccCCCccceeecceEEEEecCCCCceeeeEee
7565 Confidence 788999999999998887776443 57999999777 6 8999999888765
7566
7567
7568 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
7569 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
7570 ..++..-|..|..-+++--+. -+|+.+ +++.|..+.||+|.+. +.|-+|. +.+.|. |.|
7571 T Consensus 169 ~~~prtit~C~~p~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~f~~~~nc~f~~~-~nfT~d~--~~~wf~----~~F 241 (342)
7572 T 5X4R_A 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYT-YNITEDE--ILEWFG----ITQ 241 (342)
7573 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHSCTTCCCTTHHHHHHHHHEEEEEEEEEEE-EECCCCC--CCEEEE----EEE
7574 T ss_pred eeccCccccCCCCCeEeeeeecCCCCccCCCccccccccccchhhhcccCCcEEEEe-eecCcch--hhheEE----EEE
7575 Confidence 333344566666655542221 345444 6778899999999875 3444443 333444 999
7576
7577
7578 Q sp|P0DTC2|SPIK 195 KNID-GYFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
7579 Q Consensus 195 knid-gyfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
7580 ++.| |.|-+|-.++..+. ...+| |...|.+..-+|..++ ++ .+.|. ..++|||++|
7581 T Consensus 242 ~~~~~G~f~~Y~~d~~~~~~f~f~~~p-g~~~l~yy~viprs~~---------------~~---~~~~~-~~~ayyV~~L 301 (342)
7582 T 5X4R_A 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYSIIPHSIR---------------SI---QSDRK-AWAAFYVYKL 301 (342)
7583 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEEECCEEEC---------------CC---GGGCC-EECCEEEEEC
7584 T ss_pred EeCCceeEEEEEEecCCCcceeccccc-cccccceeEeeeeeec---------------CC---cccce-eEEEEEEEEc
7585 Confidence 9999 99999988776653 55566 7777777664554443 22 45566 7899999999
7586
7587
7588 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKSF 306 (1273)
7589 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlksf 306 (1273)
7590 .+|+|||.||+||.|++||||+-|+++|-||..+|-
7591 T Consensus 302 ~~r~yLl~Fd~nG~It~AvDCa~d~~sELkCs~~~~ 337 (342)
7592 T 5X4R_A 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYESH 337 (342)
7593 T ss_dssp EEEEEEEEECTTSCEEEEEEGGGCHHHHHHHC----
7594 T ss_pred ceeeEEEeccCCCeEEEEEecCCCcchhhcceecCC
7595 Confidence 999999999999999999999999999999998875
7596
7597
7598 No 46
7599 >6J11_C Spike glycoprotein, VH of 7D10; MERS-CoV, Antibody, VIRAL PROTEIN; HET: MAN, NAG, BMA; 3.0A {Middle East respiratory syndrome-related coronavirus}
7600 Probab=99.70 E-value=2.8e-21 Score=203.44 Aligned_cols=262 Identities=21% Similarity=0.313 Sum_probs=192.3 Template_Neff=4.300
7601
7602 Q sp|P0DTC2|SPIK 14 QCVNL-TTRTQLPPAYT----NSFTRGVYYPDKVFRSSVLHSTQDLFLPFFSNVTWFHAIHVSGTNG--T-------KRF 79 (1273)
7603 Q Consensus 14 qcvnl-ttrtqlppayt----nsftrgvyypdkvfrssvlhstqdlflpffsnvtwfhaihvsgtng--t-------krf 79 (1273)
7604 .|... ....-+++.++ -+-.+|+||||..++++..+-.|++|.+.-++.+-.- ++|++. + -.+
7605 T Consensus 12 ~C~~~~~~~~~~~~~~~~~idvs~~~G~yYp~~rvysN~tlL~qglfp~~gs~~~~y~---~~~~~~~~~~~~~~~~~~y 88 (336)
7606 T 6J11_C 12 ACIEVDIQQTFFDKTWPRPIDVSKADGIIYPQGRTYSNITITYQGLFPYQGDHGDMYV---YSAGHATGTTPQKLFVANY 88 (336)
7607 T ss_dssp BCCCEEECGGGGCCCCCCCCCGGGTTTCBCCSSCCCCSEEEEEEEEECCTTCCCEEEC---CEECCBSSSCBCSEEECSC
7608 T ss_pred ceEEeccCccccCCCCCcceecccCceeEeeCCeeEeeeeeeeeccccCCCCcceEEE---EEecCCCCCCCcceeeecC
7609 Confidence 36664 23333444554 3446899999999999999999999999988877543 233332 2 356
7610
7611
7612 Q sp|P0DTC2|SPIK 80 DNPVLPFNDGVYFASTEKSNIIRG-----------------WIFGTTLDSKT---Q------SLLIVNNATNVVI----- 128 (1273)
7613 Q Consensus 80 dnpvlpfndgvyfasteksniirg-----------------wifgttldskt---q------sllivnnatnvvi----- 128 (1273)
7614 +.+..||+||+++...+++|.-.+ ++||+|.+... + +++|+++-++.++
7615 T Consensus 89 ~~~~~~F~dGifvkv~~~~n~t~~~~~~~~~~~~~~~~ypa~~fGstf~N~s~~~~~~~~~~tlvI~P~~~g~~~~~~~c 168 (336)
7616 T 6J11_C 89 SQDVKQFANGFVVRIGAAANSTGTVIISPSTSATIRKIYPAFMLGSSVGNFSDGKMGRFFNHTLVLLPDGCGTLLRAFYC 168 (336)
7617 T ss_dssp TTCCEECTTCEEEEESTTTTSEEECSSSTTCEEEEECCCCCEEEESCEEECTTSCEEEECSEEEEEEEETTTTEEEEEEE
7618 T ss_pred CCChhhccCeEEEEEeeeeccCCCeeecCccccchhhcccceEEecccccCCCCcceeecceEEEEecCCCCceeeeEee
7619 Confidence 788999999999999887776443 57999999777 6 8999999888765
7620
7621
7622 Q sp|P0DTC2|SPIK 129 --KVCEFQFCNDPFLGVYYHKNN---KSWMES---------EFRVYSSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVF 194 (1273)
7623 Q Consensus 129 --kvcefqfcndpflgvyyhknn---kswmes---------efrvyssannctfeyvsqpflmdlegkqgnfknlrefvf 194 (1273)
7624 +.++..-|..|..-+++.-+. -+|+.+ +++.|..+.||+|.+.. .|-+|. +.+.|. |.|
7625 T Consensus 169 ~~~~rtit~C~~p~~~~~p~~~~~~~~~~~~~~~~~~~~~~~~~~f~~~~nc~f~~~~-nft~d~--~~~wf~----~~F 241 (336)
7626 T 6J11_C 169 ILEPRSGNHCPAGNSYTSFATYHTPATDCSDGNYNRNASLNSFKEYFNLRNCTFMYTY-NITEDE--ILEWFG----ITQ 241 (336)
7627 T ss_dssp EEEECCSBTSTTSTTCCCCCEEECHHHHCSSSSCCTTHHHHHHHHHEEEEEEEEEEEE-ECCCCC--CCEEEE----EEE
7628 T ss_pred eeccCccccCCCCCeEeeeeecCCCCccCCCccccccccccchhhhcccCCcEEEEee-ecCcch--hhheEe----EEE
7629 Confidence 333344566666655542221 345444 67788999999998753 444443 333443 999
7630
7631
7632 Q sp|P0DTC2|SPIK 195 KNIDG-YFKIYSKHTPINL---VRDLPQGFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYL 270 (1273)
7633 Q Consensus 195 knidg-yfkiyskhtpinl---vrdlpqgfsaleplvdlpiginitrfqtllalhrsyltpgdsssgwtagaaayyvgyl 270 (1273)
7634 ++.|| .|-+|--++..+. ...+| |...|.+..-+|..++ ++ .+.|. ..++|||++|
7635 T Consensus 242 ~~~~G~~f~~Y~~d~~~~~~f~f~~~~-g~~~l~yy~vip~s~~---------------~~---~~~~~-~~~ayyV~~L 301 (336)
7636 T 6J11_C 242 TAQGVHLFSSRYVDLYGGNMFQFATLP-VYDTIKYYSIIPHSIR---------------SI---QSDRK-AWAAFYVYKL 301 (336)
7637 T ss_dssp ETTEEEEEESTTTCTTTCCBEEEEEEC-CCSCCCEEEECCEEEC---------------CC---STTCC-EECCEEEEEC
7638 T ss_pred EeCCeeEEEEEEEccCCCcceeccccc-ceeccceeEeeeeeec---------------CC---cccce-eEEEEEEEEc
7639 Confidence 99999 9999887766653 55566 7777777664554443 22 45566 7899999999
7640
7641
7642 Q sp|P0DTC2|SPIK 271 QPRTFLLKYNENGTITDAVDCALDPLSETKCTLKS 305 (1273)
7643 Q Consensus 271 qprtfllkynengtitdavdcaldplsetkctlks 305 (1273)
7644 .+|+|||.||+||.|++||||+-|+++|-||..+|
7645 T Consensus 302 ~~~~yLl~Fd~nG~It~AvDCa~d~~sELkCst~S 336 (336)
7646 T 6J11_C 302 QPLTFLLDFSVDGYIRRAIDCGFNDLSQLHCSYES 336 (336)
7647 T ss_dssp EEEEEEEEECSSSCEEEEEETTSSHHHHHHHHHCC
7648 T ss_pred ceeeEEEeccCCCeEEEEEecCCCcchhheeeecC
7649 Confidence 99999999999999999999999999999998764
7650
7651
7652 No 47
7653 >5GYQ_A Spike glycoprotein; bat coronavirus HKU9, putative receptor; HET: NAG; 2.1A {Bat coronavirus HKU9}
7654 Probab=99.70 E-value=4.2e-21 Score=188.88 Aligned_cols=108 Identities=29% Similarity=0.580 Sum_probs=104.5 Template_Neff=2.900
7655
7656 Q sp|P0DTC2|SPIK 332 ITNLCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCFTNVYADSFVIRGDEVRQIA 411 (1273)
7657 Q Consensus 332 itnlcpfgevfnatrfasvyawnrkrisncvadysvlynsasfstfkcygvsptklndlcftnvyadsfvirgdevrqia 411 (1273)
7658 |...|+|.++++ .++.+++.|.|+.++||..|+++|++.....+|+||||||.||.+.||..|+.|.|.|..+..++++
7659 T Consensus 2 ~~~~C~~~~~l~-~~~PsP~nWeR~~fsNCnFN~S~Llslv~v~sf~C~gISPskLasmCfsSVTiD~FaIp~s~~~~Lq 80 (176)
7660 T 5GYQ_A 2 IQSYCTPPYSVL-QDPPQPVVWRRYMLYDCVFDFTVVVDSLPTHQLQCYGVSPRRLASMCYGSVTLDVMRINETHLNNLF 80 (176)
7661 T ss_dssp CCEECCCCHHHH-HSCCCGGGCEEEEECSEEECGGGGTTSSCEEEEEEESSCHHHHTTSCBSEEEEEEEEECHHHHHHHH
7662 T ss_pred CCCCCCCChHhc-CCCCCCceeEEEEEeccCCchHHHHhhceeeeeeeeCCCHHHHhhcccceeEEEEEEeChHHHHhhc
7663 Confidence 567899999999 9999999999999999999999999999999999999999999999999999999999999999999
7664
7665
7666 Q sp|P0DTC2|SPIK 412 PGQTGKIADYNYKLPDDFTGCVIAWNSNN 440 (1273)
7667 Q Consensus 412 pgqtgkiadynyklpddftgcviawnsnn 440 (1273)
7668 +|++|-|++||||+|+||+||+++|+-+.
7669 T Consensus 81 ~GssG~i~~yNYKlp~~f~gC~l~y~l~~ 109 (176)
7670 T 5GYQ_A 81 NRVPDTFSLYNYALPDNFYGCLHAFYLNS 109 (176)
7671 T ss_dssp HTCCCHHHHHTCCCCTTCCEEEEEEEEEE
7672 T ss_pred CCCCcHHHhccccCCCCCCceEEEEEcCC
7673 Confidence 99999999999999999999999997653
7674
7675
7676 No 48
7677 >5ZVK_A Human Coronavirus MERS HR1 motif; MERS, Spike protein, S2 domain; 3.31A {Middle East respiratory syndrome-related coronavirus}
7678 Probab=99.68 E-value=7.3e-21 Score=169.61 Aligned_cols=79 Identities=56% Similarity=0.816 Sum_probs=69.9 Template_Neff=3.000
7679
7680 Q sp|P0DTC2|SPIK 910 GVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVE 988 (1273)
7681 Q Consensus 910 gvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkve 988 (1273)
7682 |+|++||.||||+||+.||.|+|.|++.+.++++||.|+|||||++++||+.|+.||+.|||||||.++||.+|||++|
7683 T Consensus 2 glt~~VL~~NQk~iA~sFN~A~~~i~~~~~t~~~AL~kiQ~VVN~q~~aL~~L~~qL~~NFgAISssI~dIy~RLd~le 80 (80)
7684 T 5ZVK_A 2 GITQQVLSENQKLIANKFNQALGAMQTGFTTTNEAFRKVQDAVNNNAQALSKLASELSNTFGAISASIGDIIQRLDVLE 80 (80)
7685 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-------
7686 T ss_pred CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHhcC
7687 Confidence 7899999999999999999999999999999999999999999999999999999999999999999999999999986
7688
7689
7690 No 49
7691 >2BEZ_C E2 GLYCOPROTEIN; MEMBRANE FUSION, SEVERE ACUTE RESPIRATORY; 1.6A {SARS CORONAVIRUS} SCOP: h.3.3.1
7692 Probab=99.63 E-value=8.5e-20 Score=162.03 Aligned_cols=77 Identities=88% Similarity=1.101 Sum_probs=75.2 Template_Neff=3.000
7693
7694 Q sp|P0DTC2|SPIK 914 NVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAE 990 (1273)
7695 Q Consensus 914 nvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveae 990 (1273)
7696 +||.||||+||+.||.|++.|+..++++++||.|+|||||++++||+.|+.||+.|||||||.++||.+|||++||.
7697 T Consensus 1 ~VL~~NQk~iA~sFN~A~~~i~~~~~t~s~AL~kiQ~VVN~q~~aL~~L~~qL~~nFgAISssI~dIy~RLd~leAd 77 (77)
7698 T 2BEZ_C 1 NVLYENQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAE 77 (77)
7699 T ss_dssp CCSSSHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
7700 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHHHHHHHHHHHHHHHHhcC
7701 Confidence 58999999999999999999999999999999999999999999999999999999999999999999999999984
7702
7703
7704 No 50
7705 >6M1V_A spike protein; 2019-nCoV, spike protein, fusion core; 1.5A {Severe acute respiratory syndrome coronavirus 2}
7706 Probab=99.60 E-value=2.8e-19 Score=168.19 Aligned_cols=98 Identities=56% Similarity=0.575 Sum_probs=68.4 Template_Neff=3.400
7707
7708 Q sp|P0DTC2|SPIK 917 YENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEVQIDRL 996 (1273)
7709 Q Consensus 917 yenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndilsrldkveaevqidrl 996 (1273)
7710 .||||+||+.||.|+|.|++.++++++||.|+|||||++++||+.|+.||+.|||||||.+. |++||.+|+||+
7711 T Consensus 1 ~~NQk~lA~sFN~A~~~i~~~~~t~~~Al~kiQ~VVN~q~~aL~~L~~qL~~nf~aisssi~------~~lea~~q~drl 74 (119)
7712 T 6M1V_A 1 MENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLLVPRGSGGSGGS------GGLEVLFQGPDV 74 (119)
7713 T ss_dssp CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCC--------------------------
7714 T ss_pred ChHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhccCCCcchhh------hhHHHhhcCCCc
7715 Confidence 38999999999999999999999999999999999999999999999999999999999977 899999999999
7716
7717
7718 Q sp|P0DTC2|SPIK 997 ITGRLQSLQTYVTQQLIRAAEIRA 1020 (1273)
7719 Q Consensus 997 itgrlqslqtyvtqqliraaeira 1020 (1273)
7720 ++|||..+..++++-....++++.
7721 T Consensus 75 itgrLsaLNatvldL~~Ei~~Lqe 98 (119)
7722 T 6M1V_A 75 DLGDISGINASVVNIQKEIDRLNE 98 (119)
7723 T ss_dssp ----CTTCCCCCCCCHHHHHHHHH
7724 T ss_pred CCCChHHhhHHHHHHHHHHHHHHH
7725 Confidence 999999999999887666655543
7726
7727
7728 No 51
7729 >5ZUV_A Spike glycoprotein,EK1, Spike glycoprotein,inhibitor EK1; Human Coronavirus 229E, Spike protein; 2.21A {Human coronavirus 229E}
7730 Probab=99.56 E-value=1.2e-18 Score=166.05 Aligned_cols=83 Identities=47% Similarity=0.646 Sum_probs=77.2 Template_Neff=2.400
7731
7732 Q sp|P0DTC2|SPIK 914 NVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLND 979 (1273)
7733 Q Consensus 914 nvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlnd 979 (1273)
7734 +||.||||+||+.||.|||.|+.. ++++++||.|+|||||++++||+.|++||+.|||||||.++|
7735 T Consensus 2 dVLq~NQkiiA~SFN~AignI~~aF~~vn~ai~qts~~~~Tva~AL~KIQdVVN~qg~AL~~Lt~QL~nNFqAISSSIqD 81 (133)
7736 T 5ZUV_A 2 DVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQA 81 (133)
7737 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
7738 T ss_pred cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
7739 Confidence 689999999999999999999966 566779999999999999999999999999999999999999
7740
7741
7742 Q sp|P0DTC2|SPIK 980 ILSRLDKVEAEVQIDRL 996 (1273)
7743 Q Consensus 980 ilsrldkveaevqidrl 996 (1273)
7744 |.+|||++||.++.++|
7745 T Consensus 82 IY~RLD~leAd~~~gsl 98 (133)
7746 T 5ZUV_A 82 IYDRLDTIQSGGRGGSL 98 (133)
7747 T ss_dssp HHHHHTCSSCCCCSCCC
7748 T ss_pred HHHHHHHHHhhhccCcc
7749 Confidence 99999999999998776
7750
7751
7752 No 52
7753 >5YL9_A Spike glycoprotein; Spike protein, 6-helical bundle, post-fusion; 1.861A {Human coronavirus 229E}
7754 Probab=99.49 E-value=1.1e-17 Score=151.89 Aligned_cols=74 Identities=51% Similarity=0.726 Sum_probs=70.0 Template_Neff=2.900
7755
7756 Q sp|P0DTC2|SPIK 914 NVLYENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLND 979 (1273)
7757 Q Consensus 914 nvlyenqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlnd 979 (1273)
7758 +||.||||+||+.||.|||.|+.. ++++++||.|+|||||++++||+.|.+||+.|||||||.++|
7759 T Consensus 2 ~VLq~NQk~iA~sFN~Aigni~~af~~vn~ai~qts~~~~tva~AL~KiQ~VVN~q~~aL~~Lt~QL~~NF~AISsSI~d 81 (89)
7760 T 5YL9_A 2 DVLQENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQAISSSIQA 81 (89)
7761 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
7762 T ss_pred cHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
7763 Confidence 689999999999999999999977 556679999999999999999999999999999999999999
7764
7765
7766 Q sp|P0DTC2|SPIK 980 ILSRLDKV 987 (1273)
7767 Q Consensus 980 ilsrldkv 987 (1273)
7768 |.+|||++
7769 T Consensus 82 Iy~RLd~l 89 (89)
7770 T 5YL9_A 82 IYDRLDTI 89 (89)
7771 T ss_dssp HHHHHHHC
7772 T ss_pred HHHHHhcC
7773 Confidence 99999974
7774
7775
7776 No 53
7777 >1WDF_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.5A {Murine hepatitis virus} SCOP: h.3.3.1
7778 Probab=99.16 E-value=2.7e-14 Score=131.27 Aligned_cols=62 Identities=60% Similarity=0.836 Sum_probs=58.6 Template_Neff=2.400
7779
7780 Q sp|P0DTC2|SPIK 919 NQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDI 980 (1273)
7781 Q Consensus 919 nqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaissvlndi 980 (1273)
7782 |||.||+.||.|||.||+.++++++||.|+|||||++++||+.|+.||+.|||||||++.|.
7783 T Consensus 1 NQkiLAnsFN~AignIq~af~tts~AL~KIQdVVN~qg~AL~~Lt~QL~~NFgAISSsi~d~ 62 (95)
7784 T 1WDF_B 1 NQKMIASAFNNALGAIQDGFDATNSALGKIQSVVNANAEALNNLLNQLSNRFGAISDLSLDF 62 (95)
7785 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTCC--CCCCCG
7786 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhHchHHHHHHHH
7787 Confidence 79999999999999999999999999999999999999999999999999999999999875
7788
7789
7790 No 54
7791 >1ZVA_A E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.5A {SARS coronavirus} SCOP: h.3.3.1
7792 Probab=99.05 E-value=1.7e-13 Score=121.91 Aligned_cols=58 Identities=66% Similarity=0.811 Sum_probs=47.6 Template_Neff=4.100
7793
7794 Q sp|P0DTC2|SPIK 1144 ELDSFKEELDKYFKNHTSPDVDLGD-----ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 1201 (1273)
7795 Q Consensus 1144 eldsfkeeldkyfknhtspdvdlgd-----isginasvvniqkeidrlnevaknlneslidlq 1201 (1273)
7796 .|..|++||+|+||+++|.-.|+.+ ++++|+++++++.||+||+||+|+||||+|||+
7797 T Consensus 15 ~L~~f~~eL~~~FkaiSSsi~di~~rl~grLs~lNa~vl~l~~Ei~~L~~vik~LN~S~IdLk 77 (77)
7798 T 1ZVA_A 15 ALNTLVKQLSSNFGAISSVLNDISGGRGGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 77 (77)
7799 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHTTSCCCCTTHHHHHHHHHHHHHHHHHHHHHHHHHHHC--
7800 T ss_pred HHHHHHHHHHHHhchhhhchhhhcCCCCCChhhhcHHHHHHHHHHHHHHHHHHHHHHhhhccC
7801 Confidence 4566777777777777776655554 999999999999999999999999999999985
7802
7803
7804 No 55
7805 >5ZHY_D Spike glycoprotein,Spike glycoprotein; membrane fusion, broad-spectrum inhibitor design; 2.441A {Human coronavirus 229E}
7806 Probab=98.79 E-value=7.4e-12 Score=121.97 Aligned_cols=59 Identities=47% Similarity=0.667 Sum_probs=37.2 Template_Neff=2.300
7807
7808 Q sp|P0DTC2|SPIK 918 ENQKLIANQFNSAIGKIQDS--------------LSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSV 976 (1273)
7809 Q Consensus 918 enqklianqfnsaigkiqds--------------lsstasalgklqdvvnqnaqalntlvkqlssnfgaissv 976 (1273)
7810 ||||+||+.||.|||.|+.. ++++|+||.|+|||||+.++||+.|.+||+.||||||+-
7811 T Consensus 1 ~NQkiLAnSFN~AignIt~aF~~Vn~Ai~qts~~~~Tva~AL~KIQdVVN~Qg~ALs~Lt~QL~nNFqAIS~~ 73 (148)
7812 T 5ZHY_D 1 ENQKILAASFNKAMTNIVDAFTGVNDAITQTSQALQTVATALNKIQDVVNQQGNSLNHLTSQLRQNFQLVPRG 73 (148)
7813 T ss_dssp -----CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCC--------------
7814 T ss_pred ChHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCcccc
7815 Confidence 69999999999999999966 555679999999999999999999999999999999974
7816
7817
7818 No 56
7819 >5XJK_A Spike protein S2; VIRAL PROTEIN; NMR {Human SARS coronavirus}
7820 Probab=98.74 E-value=1.4e-11 Score=106.98 Aligned_cols=62 Identities=85% Similarity=1.326 Sum_probs=57.8 Template_Neff=4.400
7821
7822 Q sp|P0DTC2|SPIK 777 NTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYG 838 (1273)
7823 Q Consensus 777 ntqevfaqvkqiyktppikdfggfnfsqilpdpskpskrsfiedllfnkvtladagfikqyg 838 (1273)
7824 +..+++..+|+-+++|-+..|+||||+.+||.+++++.||+||||||+||.++|.||++.|.
7825 T Consensus 3 ~~~~~~s~~~~~~~l~~~~~~~~fN~s~lL~~~~~~~~RSaIEDLLF~KV~t~~~G~v~~Yk 64 (65)
7826 T 5XJK_A 3 NTREVFAQVKQMYKTPTLKYFGGFNFSQILPSPLKPTKRSFIEDLLFNKVTLADAGFMKQYG 64 (65)
7827 T ss_dssp TTGGGHHHHTTCCCCCCCSSSCCCCGGGSSCCCCCCCGGGGGGHHHHTTTSSTTHHHHHGGG
7828 T ss_pred cHHHHHHHHHHHhcCCcccccCCccccccCCCCCCCCCccHHHHHhccceeecCcchhhhhc
7829 Confidence 34678899999999999999999999999999999999999999999999999999998885
7830
7831
7832 No 57
7833 >1ZV8_K E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.94A {SARS coronavirus} SCOP: h.3.3.1
7834 Probab=98.55 E-value=1.2e-10 Score=98.26 Aligned_cols=50 Identities=82% Similarity=0.987 Sum_probs=48.5 Template_Neff=3.100
7835
7836 Q sp|P0DTC2|SPIK 919 NQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS 968 (1273)
7837 Q Consensus 919 nqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlss 968 (1273)
7838 |||+||+.||.||+.|++.++++++||.|+|||||++++||+.|..||+.
7839 T Consensus 1 NQk~iA~sFN~Ai~~i~~g~~t~~~AL~KiQ~VVN~q~~aL~~Lt~qL~~ 50 (50)
7840 T 1ZV8_K 1 NQKQIANQFNKAISQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLSS 50 (50)
7841 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
7842 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhC
7843 Confidence 79999999999999999999999999999999999999999999999963
7844
7845
7846 No 58
7847 >2IEQ_B Spike glycoprotein; Human coronavirus membrane fusion; 1.747A {Human coronavirus}
7848 Probab=98.54 E-value=1.3e-10 Score=109.56 Aligned_cols=84 Identities=33% Similarity=0.293 Sum_probs=64.1 Template_Neff=3.500
7849
7850 Q sp|P0DTC2|SPIK 921 KLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISS-VLNDIL--------SRLDKVEAEV 991 (1273)
7851 Q Consensus 921 klianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlssnfgaiss-vlndil--------srldkveaev 991 (1273)
7852 .+-.+.||.||+.||+.++++++||.|+|||||+.+++|+.|..||..||++|+. .+ ||. +|+|+.|++.
7853 T Consensus 7 t~a~~~fn~Ai~~i~~g~~tt~~AL~KIQ~VVN~q~~tL~~Ll~QL~nNF~Ais~~~l-difN~T~LNLT~Ei~~LE~ra 85 (109)
7854 T 2IEQ_B 7 VASFSSVNDAITQTAEAIHTVTIALNKIQDVVNQQGSALNHLTSQLRHNFQSGGRGSG-RGGNLTYLNLSSELKQLEAKT 85 (109)
7855 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-----------------CCCCCCHHHHHHHHHHH
7856 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcccCCCCccCC-cchHhhhcchhHHHHHHHHHH
7857 Confidence 3456899999999999999999999999999999999999999999999999999 67 999 9999999999
7858
7859
7860 Q sp|P0DTC2|SPIK 992 QIDRLITGRLQSLQ 1005 (1273)
7861 Q Consensus 992 qidrlitgrlqslq 1005 (1273)
7862 +-=+-++-.||.+-
7863 T Consensus 86 ~~L~~~~~eLq~~I 99 (109)
7864 T 2IEQ_B 86 ASLFQTTVELQGLI 99 (109)
7865 T ss_dssp HHHHHHHHHHHHHH
7866 T ss_pred HHHHHHHHHHHHHH
7867 Confidence 88888888877653
7868
7869
7870 No 59
7871 >2FXP_A Spike glycoprotein; Prefusion Intermediate, Trimer, Coiled-coil, VIRAL; NMR {SARS coronavirus} SCOP: h.3.3.1
7872 Probab=98.52 E-value=1.6e-10 Score=98.19 Aligned_cols=54 Identities=98% Similarity=1.317 Sum_probs=52.8 Template_Neff=4.100
7873
7874 Q sp|P0DTC2|SPIK 1158 NHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIK 1211 (1273)
7875 Q Consensus 1158 nhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyik 1211 (1273)
7876 |||+|+.++.++..+|++++|++.||++|+++.|+||+++|||++|++||+|||
7877 T Consensus 2 n~t~~~~~~~~l~~~N~t~LnLt~Ei~~Lq~~I~~LN~s~IdLe~Ln~~etYiK 55 (55)
7878 T 2FXP_A 2 SHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIK 55 (55)
7879 T ss_dssp CSCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTTTTCCC
7880 T ss_pred CCCCCCCCCCccccccccccchHHHHHHHHHHHHHHhhcCCCHHHhccceeecC
7881 Confidence 799999999999999999999999999999999999999999999999999998
7882
7883
7884 No 60
7885 >1WDG_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.06A {Murine hepatitis virus} SCOP: h.3.3.1
7886 Probab=98.49 E-value=2.2e-10 Score=106.06 Aligned_cols=54 Identities=57% Similarity=0.760 Sum_probs=48.6 Template_Neff=3.000
7887
7888 Q sp|P0DTC2|SPIK 919 NQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS--NFGA 972 (1273)
7889 Q Consensus 919 nqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvkqlss--nfga 972 (1273)
7890 |||+||+.||.|||.||+.++++++||.|+|||||++++||+.|..||+. |++.
7891 T Consensus 1 NQk~iA~sFN~Aigni~~~f~~~~~AL~kiQ~VVN~q~~aL~~LtNQLS~~pn~~~ 56 (94)
7892 T 1WDG_B 1 NQKMIASAFNNALGAIQDGFDATNSALGKIQSVVNANAEALNNLLNQLSLVPRGSG 56 (94)
7893 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCC------
7894 T ss_pred ChHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcCCCCCC
7895 Confidence 79999999999999999999999999999999999999999999999998 7777
7896
7897
7898 No 61
7899 >2BEQ_D E2 GLYCOPROTEIN; VIRAL PROTEIN, COILED COIL, MEMBRANE; HET: ACE; 1.6A {N/A}
7900 Probab=98.41 E-value=5.2e-10 Score=93.68 Aligned_cols=47 Identities=98% Similarity=1.271 Sum_probs=44.9 Template_Neff=3.400
7901
7902 Q sp|P0DTC2|SPIK 1166 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKW 1212 (1273)
7903 Q Consensus 1166 lgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikw 1212 (1273)
7904 ++|++.+|++++|++.||++|+++.|+||+|+|||++|++||+||||
7905 T Consensus 2 ~~~l~~~N~t~LnLs~Ei~~Lq~~I~~LN~s~IdLe~Ln~~etYiKW 48 (48)
7906 T 2BEQ_D 2 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKX 48 (48)
7907 T ss_dssp CCSCTTCCCCCCCCHHHHHHHHHHHTTGGGGEECHHHHHHHHHHHC-
7908 T ss_pred CCCccccccccccHHHHHHHHHHHHHHHHhcCCCHHHhcccchhcCC
7909 Confidence 67889999999999999999999999999999999999999999999
7910
7911
7912 No 62
7913 >2BEQ_E E2 GLYCOPROTEIN; VIRAL PROTEIN, COILED COIL, MEMBRANE; HET: ACE; 1.6A {N/A}
7914 Probab=98.41 E-value=5.2e-10 Score=93.68 Aligned_cols=47 Identities=98% Similarity=1.271 Sum_probs=44.3 Template_Neff=3.400
7915
7916 Q sp|P0DTC2|SPIK 1166 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKW 1212 (1273)
7917 Q Consensus 1166 lgdisginasvvniqkeidrlnevaknlneslidlqelgkyeqyikw 1212 (1273)
7918 ++|++.+|++++|++.||++|+++.|+||+|+|||++|++||+||||
7919 T Consensus 2 ~~~l~~~N~t~LnLs~Ei~~Lq~~I~~LN~s~IdLe~Ln~~etYiKW 48 (48)
7920 T 2BEQ_E 2 LGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKX 48 (48)
7921 T ss_dssp -CTTTTCCCCCCCCHHHHHHHHHHHHTGGGTEEEHHHHHHHHHHHC-
7922 T ss_pred CCCccccccccccHHHHHHHHHHHHHHHHhcCCCHHHhcccchhcCC
7923 Confidence 67889999999999999999999999999999999999999999999
7924
7925
7926 No 63
7927 >6LXT_F Spike protein S2; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {Severe acute respiratory syndrome coronavirus 2}
7928 Probab=97.71 E-value=1.4e-07 Score=91.83 Aligned_cols=45 Identities=98% Similarity=1.275 Sum_probs=36.7 Template_Neff=2.500
7929
7930 Q sp|P0DTC2|SPIK 1163 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYE 1207 (1273)
7931 Q Consensus 1163 dvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkye 1207 (1273)
7932 .+..|.++.+||.|...|.|+.+|||||||||||||||||||||.
7933 T Consensus 87 RLItGRLaaLna~v~q~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 131 (132)
7934 T 6LXT_F 87 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYG 131 (132)
7935 T ss_dssp ---CCCCTTCCCCCCCCHHHHHHHHHHHHHGGGGSCCCCC-----
7936 T ss_pred chhcccHHHHHHHHHHHHHHHHHHHHHHHHHhHHhchHHHhHhcC
7937 Confidence 467899999999999999999999999999999999999999994
7938
7939
7940 No 64
7941 >6LXT_C 2019-nCoV S2 subunit; 2019-nCoV, HR1 and HR2 domain; HET: PG4; 2.9A {COVID-19 virus}
7942 Probab=97.71 E-value=1.4e-07 Score=91.83 Aligned_cols=45 Identities=98% Similarity=1.275 Sum_probs=38.5 Template_Neff=2.500
7943
7944 Q sp|P0DTC2|SPIK 1163 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYE 1207 (1273)
7945 Q Consensus 1163 dvdlgdisginasvvniqkeidrlnevaknlneslidlqelgkye 1207 (1273)
7946 .+..|.++.+||.|...|.|+.+|||||||||||||||||||||.
7947 T Consensus 87 RLItGRLaaLna~v~q~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 131 (132)
7948 T 6LXT_C 87 DVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYG 131 (132)
7949 T ss_dssp CCCCCCCTTCCCCCCCCHHHHHHHHHHHHHGGGGCCCCCC-----
7950 T ss_pred chhcccHHHHHHHHHHHHHHHHHHHHHHHHHhHHhchHHHhHhcC
7951 Confidence 467899999999999999999999999999999999999999994
7952
7953
7954 No 65
7955 >4MOD_B HR1 of S protein, LINKER; MERS-CoV, Viral envelope proteins, Spike; 1.901A {Human betacoronavirus 2c EMC/2012}
7956 Probab=97.52 E-value=4.8e-07 Score=88.04 Aligned_cols=64 Identities=33% Similarity=0.482 Sum_probs=36.9 Template_Neff=3.100
7957
7958 Q sp|P0DTC2|SPIK 1142 QPELDSFKEELDKYFKNHTSPDVDL--------------------GDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 1201 (1273)
7959 Q Consensus 1142 qpeldsfkeeldkyfknhtspdvdl--------------------gdisginasvvniqkeidrlnevaknlneslidlq 1201 (1273)
7960 ...|..|++||+++||+++|.-.|+ |.++.+|+++++++.|+.+|++|.|.||||.|||+
7961 T Consensus 40 ~~aL~~l~~EL~knFkAISSsI~dIy~rld~~~~~ad~qvdrLitgrL~~LNa~~~dl~~em~~l~~vvk~LNes~idlk 119 (129)
7962 T 4MOD_B 40 AQALSKLASELSNTFGAISASIGDILVPRGSGGSGGSGGLEVLFQGPLTQINTTLLDLTYEMLSLQQVVKALNESYIDLK 119 (129)
7963 T ss_dssp HHHHHHHHHC---------------------------------------CCCCCCCCCHHHHHHHHHHHHHHHTTCCC--
7964 T ss_pred HHHHHHHHHHHHHHhCcchhhHHHhhhccCCCCCCccccchhhcCCChHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcHH
7965 Confidence 3568899999999999999987776 45777999999999999999999999999999999
7966
7967
7968 Q sp|P0DTC2|SPIK 1202 ELGK 1205 (1273)
7969 Q Consensus 1202 elgk 1205 (1273)
7970 ||-.
7971 T Consensus 120 el~~ 123 (129)
7972 T 4MOD_B 120 ELLE 123 (129)
7973 T ss_dssp ----
7974 T ss_pred HHHh
7975 Confidence 9854
7976
7977
7978 No 66
7979 >1ZVB_A E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.7A {SARS coronavirus} SCOP: h.3.3.1
7980 Probab=97.29 E-value=1.9e-06 Score=69.03 Aligned_cols=34 Identities=100% Similarity=1.192 Sum_probs=32.0 Template_Neff=3.100
7981
7982 Q sp|P0DTC2|SPIK 958 ALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEV 991 (1273)
7983 Q Consensus 958 alntlvkqlssnfgaissvlndilsrldkveaev 991 (1273)
7984 ||+.|+.||+.|||||||.++||.+|||++||.+
7985 T Consensus 1 al~~L~~qL~nnF~aISssI~di~~RLD~leA~~ 34 (34)
7986 T 1ZVB_A 1 ALNTLVKQLSSNFGAISSVLNDILSRLDKVEAEV 34 (34)
7987 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTC
7988 T ss_pred CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhcC
7989 Confidence 5889999999999999999999999999999864
7990
7991
7992 No 67
7993 >1WDG_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.06A {Murine hepatitis virus} SCOP: h.3.3.1
7994 Probab=97.10 E-value=5.1e-06 Score=77.92 Aligned_cols=47 Identities=30% Similarity=0.468 Sum_probs=29.3 Template_Neff=3.000
7995
7996 Q sp|P0DTC2|SPIK 1156 FKNHTSPDVDLGD----ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQE 1202 (1273)
7997 Q Consensus 1156 fknhtspdvdlgd----isginasvvniqkeidrlnevaknlneslidlqe 1202 (1273)
7998 .-++++...++++ +++||++.+++++|+++|+||.|.||||.|||+|
7999 T Consensus 44 LtNQLS~~pn~~~~~~~~~~iN~t~lDl~~Em~~lq~vvk~LNeS~IdLKe 94 (94)
8000 T 1WDG_B 44 LLNQLSLVPRGSGGSGGSGGLNVTLLDLTYEMNRIQDAIKKLNESYINLKE 94 (94)
8001 T ss_dssp HHTTCCC-------------------CCHHHHHHHHHHHHHHHTTCCCTTC
8002 T ss_pred HHHHHhcCCCCCCCCCCcccchhhhHHHHHHHHHHHHHHHHHHHHhhcccC
8003 Confidence 4577777777777 9999999999999999999999999999999986
8004
8005
8006 No 68
8007 >6M1V_A spike protein; 2019-nCoV, spike protein, fusion core; 1.5A {Severe acute respiratory syndrome coronavirus 2}
8008 Probab=96.99 E-value=8.6e-06 Score=78.78 Aligned_cols=49 Identities=86% Similarity=1.074 Sum_probs=35.8 Template_Neff=3.400
8009
8010 Q sp|P0DTC2|SPIK 1157 KNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGK 1205 (1273)
8011 Q Consensus 1157 knhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqelgk 1205 (1273)
8012 .+-+.+..++|+++.+|+++++++.||++|+||.|+||||+|||+||..
8013 T Consensus 67 a~~q~drlitgrLsaLNatvldL~~Ei~~LqevIk~LN~S~IDLk~~~~ 115 (119)
8014 T 6M1V_A 67 VLFQGPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELHH 115 (119)
8015 T ss_dssp ------------CTTCCCCCCCCHHHHHHHHHHHHHGGGGSCCGGGSCC
8016 T ss_pred HhhcCCCcCCCChHHhhHHHHHHHHHHHHHHHHHHHHHHHcccHHHhhc
8017 Confidence 3456677888999999999999999999999999999999999999864
8018
8019
8020 No 69
8021 >2BEQ_C E2 GLYCOPROTEIN; VIRAL PROTEIN, COILED COIL, MEMBRANE; HET: ACE; 1.6A {N/A} SCOP: h.3.3.1
8022 Probab=96.96 E-value=9.9e-06 Score=66.07 Aligned_cols=36 Identities=81% Similarity=0.995 Sum_probs=34.2 Template_Neff=3.500
8023
8024 Q sp|P0DTC2|SPIK 932 GKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLS 967 (1273)
8025 Q Consensus 932 gkiqdslsstasalgklqdvvnqnaqalntlvkqls 967 (1273)
8026 +.||+.++++++||.|+|||||++++||+.|.+||+
8027 T Consensus 2 ~~iq~gf~tta~AL~KIQ~VVN~qg~aL~~Lt~QL~ 37 (38)
8028 T 2BEQ_C 2 SQIQESLTTTSTALGKLQDVVNQNAQALNTLVKQLS 37 (38)
8029 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
8030 T ss_pred CchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhC
8031 Confidence 568999999999999999999999999999999996
8032
8033
8034 No 70
8035 >5ZVM_c Human Coronavirus SARS HR1 motif; SARS, Spike protein, S2 domain; 3.3A {Human SARS coronavirus}
8036 Probab=96.74 E-value=2.6e-05 Score=65.26 Aligned_cols=41 Identities=39% Similarity=0.648 Sum_probs=38.1 Template_Neff=3.500
8037
8038 Q sp|P0DTC2|SPIK 1165 DLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGK 1205 (1273)
8039 Q Consensus 1165 dlgdisginasvvniqkeidrlnevaknlneslidlqelgk 1205 (1273)
8040 .++|+..+|++++|++.||++|+++.|+||+++|||++|++
8041 T Consensus 4 ~~~~l~~~N~t~LnLt~Ei~~Lq~~Ik~LN~s~IDLe~Lnr 44 (44)
8042 T 5ZVM_c 4 RGGSLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKELGG 44 (44)
8043 T ss_dssp HHHCCTTCCCCCCCCHHHHHHHHHHHHHHHTTCCCCCCCTT
8044 T ss_pred CCCChhhccccccchHHHHHHHHHHHHHHHhhcCCHHHhCC
8045 Confidence 46788899999999999999999999999999999999874
8046
8047
8048 No 71
8049 >5ZVM_b Human Coronavirus SARS HR1 motif; SARS, Spike protein, S2 domain; 3.3A {Human SARS coronavirus}
8050 Probab=96.74 E-value=2.6e-05 Score=65.26 Aligned_cols=41 Identities=39% Similarity=0.648 Sum_probs=38.1 Template_Neff=3.500
8051
8052 Q sp|P0DTC2|SPIK 1165 DLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGK 1205 (1273)
8053 Q Consensus 1165 dlgdisginasvvniqkeidrlnevaknlneslidlqelgk 1205 (1273)
8054 .++|+..+|++++|++.||++|+++.|+||+++|||++|++
8055 T Consensus 4 ~~~~l~~~N~t~LnLt~Ei~~Lq~~Ik~LN~s~IDLe~Lnr 44 (44)
8056 T 5ZVM_b 4 RGGSLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKELGG 44 (44)
8057 T ss_pred CCCChhhcccccccHHHHHHHHHHHHHHHHhhccChHHhcC
8058 Confidence 46788899999999999999999999999999999999874
8059
8060
8061 No 72
8062 >2BEZ_F E2 GLYCOPROTEIN; MEMBRANE FUSION, SEVERE ACUTE RESPIRATORY; 1.6A {SARS CORONAVIRUS}
8063 Probab=96.44 E-value=8.7e-05 Score=61.42 Aligned_cols=42 Identities=100% Similarity=1.270 Sum_probs=37.4 Template_Neff=4.100
8064
8065 Q sp|P0DTC2|SPIK 1160 TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 1201 (1273)
8066 Q Consensus 1160 tspdvdlgdisginasvvniqkeidrlnevaknlneslidlq 1201 (1273)
8067 ||+..++.++..+|++++|++.||++|+++.|+||+++|||+
8068 T Consensus 1 ts~~p~~~~l~~~N~t~LnLt~Ei~~Lq~~I~~LN~slIdLe 42 (42)
8069 T 2BEZ_F 1 TSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQ 42 (42)
8070 T ss_dssp CCCCCCCCCCTTCCCCCCCCHHHHHHHHHHHHHTSTTSCCCC
8071 T ss_pred CCCCcCcccccccccccccHHHHHHHHHHHHHHHHhccccCC
8072 Confidence 455566666889999999999999999999999999999985
8073
8074
8075 No 73
8076 >6LVN_B 2019-nCoV S2 subunit; 2019-nCoV, HR2 domain, VIRUS, VIRAL; 2.47A {COVID-19 virus}
8077 Probab=96.21 E-value=0.00019 Score=58.12 Aligned_cols=35 Identities=100% Similarity=1.213 Sum_probs=32.6 Template_Neff=3.900
8078
8079 Q sp|P0DTC2|SPIK 1169 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
8080 Q Consensus 1169 isginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
8081 +..+|++++|++.||++|+++.|+||+|+|||++|
8082 T Consensus 2 ~~~~N~t~Lnlt~Ei~~lq~~I~~LN~s~IdLe~L 36 (36)
8083 T 6LVN_B 2 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 36 (36)
8084 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTC
8085 T ss_pred CcccccccccHHHHHHHHHHHHHHHHhhcCChhhC
8086 Confidence 45689999999999999999999999999999875
8087
8088
8089 No 74
8090 >1ZV8_B E2 glycoprotein; SARS coronavirus, membrane fusion, S2; 1.94A {SARS coronavirus}
8091 Probab=96.21 E-value=0.00019 Score=58.12 Aligned_cols=35 Identities=100% Similarity=1.213 Sum_probs=26.7 Template_Neff=3.900
8092
8093 Q sp|P0DTC2|SPIK 1169 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
8094 Q Consensus 1169 isginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
8095 +..+|++++|++.||++|+++.|+||+|+|||++|
8096 T Consensus 2 ~~~~N~t~Lnlt~Ei~~lq~~I~~LN~s~IdLe~L 36 (36)
8097 T 1ZV8_B 2 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 36 (36)
8098 T ss_dssp ---CCCCCCCCHHHHHHHHHHHHHGGGGCC-----
8099 T ss_pred CcccccccccHHHHHHHHHHHHHHHHhhcCChhhC
8100 Confidence 45689999999999999999999999999999875
8101
8102
8103 No 75
8104 >6LVN_A Spike protein S2; 2019-nCoV, HR2 domain, VIRUS, VIRAL; 2.47A {Severe acute respiratory syndrome coronavirus 2}
8105 Probab=96.21 E-value=0.00019 Score=58.12 Aligned_cols=35 Identities=100% Similarity=1.213 Sum_probs=32.0 Template_Neff=3.900
8106
8107 Q sp|P0DTC2|SPIK 1169 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 1203 (1273)
8108 Q Consensus 1169 isginasvvniqkeidrlnevaknlneslidlqel 1203 (1273)
8109 +..+|++++|++.||++|+++.|+||+|+|||++|
8110 T Consensus 2 ~~~~N~t~Lnlt~Ei~~lq~~I~~LN~s~IdLe~L 36 (36)
8111 T 6LVN_A 2 ISGINASVVNIQKEIDRLNEVAKNLNESLIDLQEL 36 (36)
8112 T ss_dssp CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC-
8113 T ss_pred CcccccccccHHHHHHHHHHHHHHHHhhcCChhhC
8114 Confidence 45689999999999999999999999999999875
8115
8116
8117 No 76
8118 >5YL9_B Spike glycoprotein; Spike protein, 6-helical bundle, post-fusion; 1.861A {Human coronavirus 229E}
8119 Probab=91.73 E-value=0.063 Score=48.02 Aligned_cols=41 Identities=29% Similarity=0.567 Sum_probs=34.5 Template_Neff=3.600
8120
8121 Q sp|P0DTC2|SPIK 1158 NHTSPDVDLGDISGINASVVNIQKEIDR--------------LNEVAKNLNESLIDLQ 1201 (1273)
8122 Q Consensus 1158 nhtspdvdlgdisginasvvniqkeidr--------------lnevaknlneslidlq 1201 (1273)
8123 .|+.||.+ +...|+.+.|+..||++ |.++.++||.+++||+
8124 T Consensus 4 ~~t~pdl~---ld~yN~tiLNLt~EI~~Le~rs~~L~~~~~~Lq~~I~nLN~TlVDLE 58 (59)
8125 T 5YL9_B 4 RGGVPDLV---VEQYNQTILNLTSEISTLENKSAELNYTVQKLQTLIDNINSTLVDLK 58 (59)
8126 T ss_dssp -CCCCCCC---CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTTCCCCC
8127 T ss_pred CCCCCCcc---cccccceecccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhccccC
8128 Confidence 57888884 57789999999999999 7788888888888875
8129
8130
8131 No 77
8132 >5ZUV_A Spike glycoprotein,EK1, Spike glycoprotein,inhibitor EK1; Human Coronavirus 229E, Spike protein; 2.21A {Human coronavirus 229E}
8133 Probab=89.53 E-value=0.16 Score=51.20 Aligned_cols=44 Identities=36% Similarity=0.593 Sum_probs=41.1 Template_Neff=2.400
8134
8135 Q sp|P0DTC2|SPIK 1161 SPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
8136 Q Consensus 1161 spdvdlgdisginasvvniqkeidrlnevaknlneslidlqelg 1204 (1273)
8137 ..|+..|....||.....+.-|+.||.++.|+||||.|||.|+|
8138 T Consensus 90 eAd~~~gsl~~~n~t~ldl~yem~~~~~~~k~l~~syi~lke~g 133 (133)
8139 T 5ZUV_A 90 QSGGRGGSLDQINVTFLDLEYEMKKLEEAIKKLEESYIDLKELG 133 (133)
8140 T ss_dssp SCCCCSCCCCCCCCCCCCCHHHHHHHHHHHHHHTTCCCCHHHHC
8141 T ss_pred HhhhccCccccceeeeHHHHHHHHHHHHHHHHHHHhhcchHhhC
8142 Confidence 45788899999999999999999999999999999999999987
8143
8144
8145 No 78
8146 >6MAR_D Immunoglobulin G PGT151 Fab, Heavy; Fusion protein-Fab complex, MEMBRANE PROTEIN; HET: NAG, MAN, GAL, FUC, BMA;{Homo sapiens}
8147 Probab=71.20 E-value=3 Score=42.93 Aligned_cols=29 Identities=34% Similarity=0.603 Sum_probs=12.5 Template_Neff=7.100
8148
8149 Q sp|P0DTC2|SPIK 1199 DLQELGKYEQYIKW-PWYIWLGFIAGLIAI 1227 (1273)
8150 Q Consensus 1199 dlqelgkyeqyikw-pwyiwlgfiagliai 1227 (1273)
8151 |+++|.+.+....| +|-.|++.|..++.+
8152 T Consensus 154 ~l~~l~~~~~l~~wf~~~~wl~~iki~i~i 183 (220)
8153 T 6MAR_D 154 DLLALDKWASLWNWFDISNWLWYIKIFIMI 183 (220)
8154 T ss_pred HHHhhHHHHHHHHhcChHHHHHHHHHHHHH
8155 Confidence 44444444444333 334444444433333
8156
8157
8158 No 79
8159 >6DCQ_D Envelope glycoprotein gp160, Immunoglobulin G; HIV-1, Glycoprotein, Env, VIRAL PROTEIN; HET: NAG, GAL, BMA, FUC, MAN;{Human immunodeficiency virus 1}
8160 Probab=68.19 E-value=3.9 Score=45.14 Aligned_cols=49 Identities=29% Similarity=0.335 Sum_probs=25.2 Template_Neff=6.700
8161
8162 Q sp|P0DTC2|SPIK 1197 LIDLQELGKYEQYIKW-PWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLK 1245 (1273)
8163 Q Consensus 1197 lidlqelgkyeqyikw-pwyiwlgfiagliaivmvtimlccmtsccsclk 1245 (1273)
8164 ..|++++.+......| .+..|++.|-.+|.||+..|.|-|+..|.+|..
8165 T Consensus 146 ~~~l~~l~~w~~~~~wf~i~~wl~yiki~i~iv~gli~lri~~~~~~~~~ 195 (352)
8166 T 6DCQ_D 146 EKDLLALDKWTNLWNWFGISNWLWYIRIFIMIVGGLIGLRIIFAVLSVIN 195 (352)
8167 T ss_pred HHHHHHhHhhhhhHhhhCHhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8168 Confidence 3455555555554333 334455554444555555555655555555543
8169
8170
8171 No 80
8172 >6NIJ_B PGT145 Fab heavy chain, PGT145; HIV-1, antibody, glycoprotein, IMMUNE SYSTEM; HET: NAG, BMA; 5.7A {Homo sapiens}
8173 Probab=68.17 E-value=3.9 Score=44.93 Aligned_cols=51 Identities=27% Similarity=0.312 Sum_probs=26.1 Template_Neff=6.800
8174
8175 Q sp|P0DTC2|SPIK 1197 LIDLQELGKYEQYIKW-PWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGC 1247 (1273)
8176 Q Consensus 1197 lidlqelgkyeqyikw-pwyiwlgfiagliaivmvtimlccmtsccsclkgc 1247 (1273)
8177 ..|++++.+......| .|..|++.|-.++.||+..|.|-|+..|.+|...+
8178 T Consensus 146 ~~~l~~l~~w~~~~~wf~i~~w~~yiki~i~iv~gli~lrii~~~~~~~~~~ 197 (345)
8179 T 6NIJ_B 146 EQELLELDKWASLWNWFDITKWLWYIKIFIMIVGGLIGLRIVFTVLSIVNRI 197 (345)
8180 T ss_pred HHHHHHHHHhhhHHhhcChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8181 Confidence 3455555555554443 34445555544555555556666655555554443
8182
8183
8184 No 81
8185 >1WDF_B E2 glycoprotein; MHV, coronavirus, heptad repeat, fusion; 2.5A {Murine hepatitis virus} SCOP: h.3.3.1
8186 Probab=63.13 E-value=5.7 Score=39.08 Aligned_cols=56 Identities=27% Similarity=0.481 Sum_probs=44.4 Template_Neff=2.400
8187
8188 Q sp|P0DTC2|SPIK 1144 ELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQE 1202 (1273)
8189 Q Consensus 1144 eldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnevaknlneslidlqe 1202 (1273)
8190 .|......|.+-|..-.|. +.|...||.....+--|+.|+..+.|.||||.|||.|
8191 T Consensus 40 AL~~Lt~QL~~NFgAISSs---i~d~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ 95 (95)
8192 T 1WDF_B 40 ALNNLLNQLSNRFGAISDL---SLDFEKLNVTLLDLTYEMNRIQDAIKKLNESYINLKE 95 (95)
8193 T ss_dssp HHHHHHHHHHHHTCC--CC---CCCGGGCCCCCCCCHHHHHHHHHHHHHHHTTCCCTTC
8194 T ss_pred HHHHHHHHHHHhHchHHHH---HHHHHHHchHHHHHHHHHHHHHHHHHHHHHHhhcccC
8195 Confidence 4555666777777666553 5667788999999999999999999999999999975
8196
8197
8198 No 82
8199 >6GY6_C XaxA, XaxB; bacterial toxin, pore forming-toxins, TOXIN; 4.0A {Xenorhabdus nematophila ATCC 19061}
8200 Probab=57.97 E-value=8.2 Score=41.00 Aligned_cols=24 Identities=17% Similarity=0.426 Sum_probs=14.9 Template_Neff=9.300
8201
8202 Q sp|P0DTC2|SPIK 1172 INASVVNIQKEIDRLNEVAKNLNE 1195 (1273)
8203 Q Consensus 1172 inasvvniqkeidrlnevaknlne 1195 (1273)
8204 +++.+..++++|++|++-.+.++.
8205 T Consensus 232 l~~~i~~L~~~I~~l~~~I~~~~~ 255 (424)
8206 T 6GY6_C 232 LSTTIKDLQSKIDEKNKEIDQFQK 255 (424)
8207 T ss_pred chHHHHHHHHHHHHHHHHHHHHHH
8208 Confidence 355666777777777666555443
8209
8210
8211 No 83
8212 >6OJ7_A Fusion glycoprotein F0; Fusion protein, fusion inhibitor, six-helix; 1.45A {N/A}
8213 Probab=57.49 E-value=8.5 Score=34.15 Aligned_cols=29 Identities=17% Similarity=0.297 Sum_probs=22.5 Template_Neff=4.500
8214
8215 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8216 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8217 =|.|+.+++++++.++-|+.++||.+|.+
8218 T Consensus 17 TNeAV~~L~~g~~~l~~Av~~iQd~IN~~ 45 (53)
8219 T 6OJ7_A 17 TNKAVVSLSNGVSVLTSKVLDLKNYIDKQ 45 (53)
8220 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8221 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHhhh
8222 Confidence 36778888888888888888888877753
8223
8224
8225 No 84
8226 >1G2C_W TWO HEPTAD REPEATS OF HRSV; membrane fusion, pneumovirus, HRSV, Viral; 2.3A {Human respiratory syncytial virus} SCOP: h.3.2.1
8227 Probab=57.47 E-value=8.5 Score=34.10 Aligned_cols=29 Identities=17% Similarity=0.297 Sum_probs=22.4 Template_Neff=4.400
8228
8229 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8230 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8231 =|.|+.+++++++.++-|+.++||.+|.+
8232 T Consensus 17 TNeAV~~L~~g~~~~~~Av~~iQd~IN~~ 45 (52)
8233 T 1G2C_W 17 TNKAVVSLSNGVSVLTSKVLDLKNYIDKQ 45 (52)
8234 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHCCCCC
8235 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHhhh
8236 Confidence 46778888888888888888888877753
8237
8238
8239 No 85
8240 >6NYX_H Fusion glycoprotein F0; Fusion protein, fusion inhibitor, six-helix; HET: PEG, PG4; 1.85A {N/A}
8241 Probab=57.31 E-value=8.6 Score=34.12 Aligned_cols=29 Identities=31% Similarity=0.434 Sum_probs=23.7 Template_Neff=4.500
8242
8243 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8244 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8245 =|.|+.+++++++.++-|+.++||.+|.+
8246 T Consensus 17 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 45 (53)
8247 T 6NYX_H 17 TNKAVQSVQSSIGNLIVAIKSVQDYVNKE 45 (53)
8248 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
8249 Confidence 47788888888888888888888888754
8250
8251
8252 No 86
8253 >6O40_A Fusion glycoprotein F0; Fusion protein, fusion inhibitor, six-helix; 1.2A {N/A}
8254 Probab=57.31 E-value=8.6 Score=34.12 Aligned_cols=29 Identities=31% Similarity=0.434 Sum_probs=23.7 Template_Neff=4.500
8255
8256 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8257 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8258 =|.|+.+++++++.++-|+.++||.+|.+
8259 T Consensus 17 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 45 (53)
8260 T 6O40_A 17 TNKAVQSVQSSIGNLIVAIKSVQDYVNKE 45 (53)
8261 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
8262 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
8263 Confidence 47788888888888888888888888754
8264
8265
8266 No 87
8267 >6GY8_A XaxA; bacterial toxin, pore forming-toxins, TOXIN; 2.5A {Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 / LMG 1036 / NCIB 9965 / AN6)}
8268 Probab=54.96 E-value=10 Score=39.70 Aligned_cols=22 Identities=18% Similarity=0.404 Sum_probs=13.4 Template_Neff=9.700
8269
8270 Q sp|P0DTC2|SPIK 1173 NASVVNIQKEIDRLNEVAKNLN 1194 (1273)
8271 Q Consensus 1173 nasvvniqkeidrlnevaknln 1194 (1273)
8272 ++.+..++++|++|++-.+.++
8273 T Consensus 233 ~~~i~~L~~~I~~l~~~I~~~~ 254 (408)
8274 T 6GY8_A 233 STTIKDLQSKIDEKNKEIDQFQ 254 (408)
8275 T ss_dssp HHHHHHHHHHHHHHHHHHHHHH
8276 T ss_pred hHHHHHHHHHHHHHHHHHHHHH
8277 Confidence 5556666777776666555443
8278
8279
8280 No 88
8281 >6PWU_E Envelope glycoprotein gp160, Antibody PG16; HIV-1, ENV, VIRAL PROTEIN; HET: NAG, MAN, BMA, FUC, GAL;{Human immunodeficiency virus 1}
8282 Probab=52.04 E-value=12 Score=46.57 Aligned_cols=53 Identities=26% Similarity=0.308 Sum_probs=30.8 Template_Neff=5.500
8283
8284 Q sp|P0DTC2|SPIK 1196 SLIDLQELGKYEQYIKW-PWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCC 1248 (1273)
8285 Q Consensus 1196 slidlqelgkyeqyikw-pwyiwlgfiagliaivmvtimlccmtsccsclkgcc 1248 (1273)
8286 ...||++|.+....-.| .|-.|++.|-.+|.|+...|.|-++..|+++...++
8287 T Consensus 651 nek~l~~Ld~w~~l~~Wf~it~Wl~yIKi~i~Iv~gliglrii~~v~~~v~~~r 704 (858)
8288 T 6PWU_E 651 NEQELLELDKWANLWNWFDISNWLWYIKIFIMIVGGLIGLRIVFAVLSVINRVR 704 (858)
8289 T ss_pred HHHHHHchHHHHHHHHhhcHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
8290 Confidence 34566667666665444 344566666666666666666666666666554443
8291
8292
8293 No 89
8294 >3EUH_B Chromosome partition protein mukF, MukE; Chromosome condensation, condensin, non-SMC subunit; HET: GLY; 2.9A {Escherichia coli}
8295 Probab=52.03 E-value=12 Score=44.15 Aligned_cols=126 Identities=22% Similarity=0.336 Sum_probs=81.9 Template_Neff=3.500
8296
8297 Q sp|P0DTC2|SPIK 858 LTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLI--------ANQFNS 929 (1273)
8298 Q Consensus 858 ltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqkli--------anqfns 929 (1273)
8299 |+++-..+.+|+-.-..+| ..|.-...|--..-+-|.+ -.+--|.||-.+|.++-|.|..+ ...+.+
8300 T Consensus 125 LS~~l~~va~eL~~a~~aA-~e~~~e~~W~~~V~apLky----SV~ei~d~Id~~QR~mDeqq~~vk~eIa~LL~qDW~~ 199 (440)
8301 T 3EUH_B 125 LSMQLSIVAGELKRAADAA-EEGGDEFHWHRNVYAPLKY----SVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRA 199 (440)
8302 T ss_dssp HHHHHHHHHHHHHHHHHHH-HTCCCHHHHCCCCCHCCCC----CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHGGG
8303 T ss_pred HHHHHHHHHHHHHHHHHHH-HhcCCHHHHHhhccccccc----cHHHHHHhcchhHHHHHHHHHHHHHHHHHHHHHHHHH
8304 Confidence 3344444455554444444 3333455676665555544 44567899999999999988543 345667
8305
8306
8307 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSS------NFGAISSVLNDILSRLDKVE 988 (1273)
8308 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvkqlss------nfgaissvlndilsrldkve 988 (1273)
8309 ||..-+.-|+.|++.|..|||.+......|.++...+.+ ....+..++-++..+||.+.
8310 T Consensus 200 AI~~Ce~LL~eTs~tLrELqdtL~aagd~lq~~Ll~IQ~~~~~~~~l~~v~~~~~~Lq~kLDrI~ 264 (440)
8311 T 3EUH_B 200 AISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRII 264 (440)
8312 T ss_dssp GHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHSCSCGGGHHHHHHHHHHHHHHH
8313 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHcCCcchHHHHHHHHHHHHHHHHHH
8314 Confidence 888999999999999999999999888777766655432 22224445555555555544
8315
8316
8317 No 90
8318 >3MAW_A Fusion glycoprotein F0; Fusion protein, class I, paramyxovirus; HET: NAG, NDG; 3.5A {Newcastle disease virus}
8319 Probab=50.68 E-value=13 Score=43.97 Aligned_cols=76 Identities=29% Similarity=0.351 Sum_probs=26.5 Template_Neff=4.900
8320
8321 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8322 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8323 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.++++ .-|.-...=|.|+.++++.++.++.|+.++||-+|.
8324 T Consensus 83 ~~Rf~G~iig~~ALGVAtaaqiTA~vAl~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Av~~lQd~IN~ 157 (483)
8325 T 3MAW_A 83 QGRFIGAIIGSVALGVATAAQITAASALIQANQ---NAANIL--RLKESITATNEAVHEVTDGLSQLAVAVGKMQQFVND 157 (483)
8326 T ss_dssp -------------------------------CC---THHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8327 T ss_pred cceeeeehHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8328 Confidence 345678888888888888888876544321100 001111 011112345778888888888888888888888875
8329
8330
8331 Q sp|P0DTC2|SPIK 955 N 955 (1273)
8332 Q Consensus 955 n 955 (1273)
8333 +
8334 T Consensus 158 ~ 158 (483)
8335 T 3MAW_A 158 Q 158 (483)
8336 T ss_dssp H
8337 T ss_pred h
8338 Confidence 4
8339
8340
8341 No 91
8342 >6EK7_A YaxA; pathogens, pore forming toxins, alpha-helical; HET: MPD; 1.8A {Yersinia enterocolitica}
8343 Probab=49.86 E-value=14 Score=39.26 Aligned_cols=23 Identities=13% Similarity=0.316 Sum_probs=12.9 Template_Neff=9.300
8344
8345 Q sp|P0DTC2|SPIK 1172 INASVVNIQKEIDRLNEVAKNLN 1194 (1273)
8346 Q Consensus 1172 inasvvniqkeidrlnevaknln 1194 (1273)
8347 .+..+..++++|++|++-.+.++
8348 T Consensus 234 ~~~~i~~L~~~I~~l~~~I~~~~ 256 (410)
8349 T 6EK7_A 234 MRKSIKELDEKIKEKRQRIEQLK 256 (410)
8350 T ss_dssp CHHHHHHHHHHHHHHHHHHHHTH
8351 T ss_pred chHHHHHHHHHHHHHHHHHHHHH
8352 Confidence 34455666666666665544443
8353
8354
8355 No 92
8356 >1SVF_C SV5 FUSION PROTEIN; PARAMYXOVIRUS, FUSION, SV5, COILED-COIL, Viral; 1.4A {Simian virus 5 (strain W3)} SCOP: h.3.2.1
8357 Probab=49.38 E-value=14 Score=34.05 Aligned_cols=29 Identities=24% Similarity=0.340 Sum_probs=21.7 Template_Neff=4.200
8358
8359 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8360 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8361 =|.|+.+++++++.++.|+.++||.+|.+
8362 T Consensus 26 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 54 (64)
8363 T 1SVF_C 26 TNAAVADVVQATQSLGTAVQAVQDHINSV 54 (64)
8364 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
8365 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
8366 Confidence 46677777888888888888888877653
8367
8368
8369 No 93
8370 >1SVF_A SV5 FUSION PROTEIN; PARAMYXOVIRUS, FUSION, SV5, COILED-COIL, Viral; 1.4A {Simian virus 5 (strain W3)} SCOP: h.3.2.1
8371 Probab=49.38 E-value=14 Score=34.05 Aligned_cols=29 Identities=24% Similarity=0.340 Sum_probs=21.7 Template_Neff=4.200
8372
8373 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8374 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8375 =|.|+.+++++++.++.|+.++||.+|.+
8376 T Consensus 26 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 54 (64)
8377 T 1SVF_A 26 TNAAVADVVQATQSLGTAVQAVQDHINSV 54 (64)
8378 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
8379 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
8380 Confidence 46677777888888888888888877653
8381
8382
8383 No 94
8384 >2FYZ_E Fusion glycoprotein F0; Mumps virus fusion protein core; 2.2A {Mumps virus}
8385 Probab=48.54 E-value=15 Score=33.83 Aligned_cols=29 Identities=24% Similarity=0.274 Sum_probs=22.0 Template_Neff=4.200
8386
8387 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8388 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8389 =|.|+.+++++++.++-|+.++||.+|.+
8390 T Consensus 29 TNeAV~~l~~g~~~~~~Av~~iQd~IN~~ 57 (63)
8391 T 2FYZ_E 29 TNRAVFEVKEGTQRLAIAVQAIQDHINTI 57 (63)
8392 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHTTT
8393 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHh
8394 Confidence 46777788888888888888888877753
8395
8396
8397 No 95
8398 >2B9B_B Parainfluenza Virus 5 F Protein; fusion protein, pre-fusion conformation, VIRAL; HET: NAG; 2.85A {Simian virus 5}
8399 Probab=48.31 E-value=15 Score=43.73 Aligned_cols=76 Identities=21% Similarity=0.253 Sum_probs=40.5 Template_Neff=4.600
8400
8401 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8402 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8403 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.++++ .-|.-...=|.|+.++++.++.++-|+.++||-+|.
8404 T Consensus 79 ~~Rf~G~iig~~ALGVATaAqiTA~vAL~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Av~~iQd~IN~ 153 (497)
8405 T 2B9B_B 79 RRRFAGVVIGLAALGVATAAQVTAAVALVKANE---NAAAIL--NLKNAIQKTNAAVADVVQATQSLGTAVQAVQDHINS 153 (497)
8406 T ss_dssp --CCCSCCCCGGGGCEEEHHHHHHHHHHHHHHH---HHHHHT--TSHHHHHHSCCSECEEE--------EECSSHHHHHH
8407 T ss_pred chhhHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8408 Confidence 445788888888999998888876554321100 001110 001112245778888899999999999999988875
8409
8410
8411 Q sp|P0DTC2|SPIK 955 N 955 (1273)
8412 Q Consensus 955 n 955 (1273)
8413 +
8414 T Consensus 154 ~ 154 (497)
8415 T 2B9B_B 154 V 154 (497)
8416 T ss_dssp H
8417 T ss_pred c
8418 Confidence 4
8419
8420
8421 No 96
8422 >5YZC_B glycoprotein F2, glycoprotein F1,measles virus; glycoprotein, viral protein, fusion protein; HET: NAG, 95C; 2.334A {Measles virus (strain Ichinose-B95a)}
8423 Probab=47.22 E-value=16 Score=42.71 Aligned_cols=73 Identities=23% Similarity=0.281 Sum_probs=47.9 Template_Neff=4.700
8424
8425 Q sp|P0DTC2|SPIK 878 LAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8426 Q Consensus 878 lagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8427 ++|.|..+..+|.+.|.||--|..+.--- --.++++ .-|.-...=|.|+.++++.++.++.|+.++||-+|.+
8428 T Consensus 1 ~~g~~ig~~algvataaqita~~al~~a~---~na~~i~--~lk~si~~tn~AV~~L~~g~~~~~~AV~~lQd~IN~~ 73 (419)
8429 T 5YZC_B 1 FAGVVLAGAALGVATAAQITAGIALHQSM---LNSQAID--NLRASLETTNQAIEAIRQAGQEMILAVQGVQDYINNE 73 (419)
8430 T ss_dssp --CEEECHHHHCCCCHHHHHHHHHHHHHS---CCHHHHH--HHHHHHHTCCCSEEEECCTTSCCEEEEETTHHHCCCC
8431 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHh
8432 Confidence 46778888889988888887655432110 0011111 1111223458899999999999999999999999854
8433
8434
8435 No 97
8436 >1T98_B Chromosome partition protein mukF; WINGED HELIX, HELIX-TURN HELIX, DOMAIN; HET: MSE; 2.9A {Escherichia coli} SCOP: a.47.6.1, a.4.5.65
8437 Probab=46.81 E-value=16 Score=41.26 Aligned_cols=104 Identities=23% Similarity=0.322 Sum_probs=67.4 Template_Neff=3.500
8438
8439 Q sp|P0DTC2|SPIK 858 LTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIAN--------QFNS 929 (1273)
8440 Q Consensus 858 ltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian--------qfns 929 (1273)
8441 |+++-..+.+|+-.-..+|. .|.=-..|--..-|-|.+ -.+--|.||..+|-++-|.|..+.+ .+.+
8442 T Consensus 125 LS~ql~~va~eL~~a~~AA~-e~gde~~W~~~V~apLky----SV~eifd~Id~~QR~mDeqQ~~vk~eIA~LL~~DW~~ 199 (287)
8443 T 1T98_B 125 LSMQLSIVAGELKRAADAAE-EGGDEFHWHRNVYAPLKY----SVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRA 199 (287)
8444 T ss_dssp HHHHHHHHHHHHHHHHHHHH-SCCSHHHHCCCCCHCCCC----CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHTC-----
8445 T ss_pred HHHHHHHHHHHHHHHHHHHH-hcCCHHHHHhhccccccc----cHHHHHHhcchHHHHHHHHHHHHHHHHHHHHCccHHH
8446 Confidence 34444445555444434443 333345676665555544 3456789999999999999865443 3457
8447
8448
8449 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQL 966 (1273)
8450 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvkql 966 (1273)
8451 ||..-+.-|+.|++.|..|||........|.++...+
8452 T Consensus 200 AI~~Ce~LL~eTs~tLrELqdtL~aagd~lq~~Ll~I 236 (287)
8453 T 1T98_B 200 AISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRI 236 (287)
8454 T ss_dssp -CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8455 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8456 Confidence 8888899999999999999999887776666554443
8457
8458
8459 No 98
8460 >1T98_A Chromosome partition protein mukF; WINGED HELIX, HELIX-TURN HELIX, DOMAIN; 2.9A {Escherichia coli} SCOP: a.47.6.1, a.4.5.65
8461 Probab=46.81 E-value=16 Score=41.26 Aligned_cols=104 Identities=23% Similarity=0.322 Sum_probs=70.3 Template_Neff=3.500
8462
8463 Q sp|P0DTC2|SPIK 858 LTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIAN--------QFNS 929 (1273)
8464 Q Consensus 858 ltvlpplltdemiaqytsallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklian--------qfns 929 (1273)
8465 |+++-..+.+|+-.-..+|. .|.=-..|--..-|-|.+ -.+--|.||..+|-++-|.|..+.+ .+.+
8466 T Consensus 125 LS~ql~~va~eL~~a~~AA~-e~gde~~W~~~V~apLky----SV~eifd~Id~~QR~mDeqQ~~vk~eIA~LL~~DW~~ 199 (287)
8467 T 1T98_A 125 LSMQLSIVAGELKRAADAAE-EGGDEFHWHRNVYAPLKY----SVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRA 199 (287)
8468 T ss_pred HHHHHHHHHHHHHHHHHHHH-hCCCHHHHHhhccccccc----cHHHHHHhcchhHHHHHHHHHHHHHHHHHHHcccHHH
8469 Confidence 34444445555444434443 333345676665555544 3456789999999999999865443 3457
8470
8471
8472 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQL 966 (1273)
8473 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvkql 966 (1273)
8474 ||..-+.-|+.|++.|..|||........|.++...+
8475 T Consensus 200 AI~~Ce~LL~eTs~tLrELqdtL~aagd~lq~~Ll~I 236 (287)
8476 T 1T98_A 200 AISSCELLLSETSGTLRELQDTLEAAGDKLQANLLRI 236 (287)
8477 T ss_pred HHHHHHHHHHHHhhHHHHHHHHHHHhHHHHHHHHHHH
8478 Confidence 8888899999999999999999887776666554443
8479
8480
8481 No 99
8482 >1G5G_F FUSION PROTEIN; fusion protein, NDV, Newcastle disease; HET: BMA, NAG; 3.3A {Newcastle disease virus} SCOP: f.12.1.1, h.3.2.1
8483 Probab=45.56 E-value=18 Score=42.92 Aligned_cols=76 Identities=30% Similarity=0.372 Sum_probs=15.9 Template_Neff=4.900
8484
8485 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8486 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8487 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.++++ .-|.-...=|.|+.++++.++.++-|+.++||-+|.
8488 T Consensus 83 ~~Rf~G~iig~~ALGVAtaAqiTA~vAl~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Av~~iQd~IN~ 157 (481)
8489 T 1G5G_F 83 QGRLIGAIIGGVALGVATAAQITAASALIQANQ---NAANIL--RLKESIAATNEAVHEVTNGLSQLAVAVGKMQQFVND 157 (481)
8490 T ss_dssp --------------------------------------------------------------CHHHHHHHHHHHHHHHHH
8491 T ss_pred cceehhhHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8492 Confidence 345678888888889888888876544321100 001110 011112234778888888888888888888888875
8493
8494
8495 Q sp|P0DTC2|SPIK 955 N 955 (1273)
8496 Q Consensus 955 n 955 (1273)
8497 +
8498 T Consensus 158 ~ 158 (481)
8499 T 1G5G_F 158 Q 158 (481)
8500 T ss_dssp H
8501 T ss_pred h
8502 Confidence 4
8503
8504
8505 No 100
8506 >5EVM_F Fusion glycoprotein F0; fusion protein, Nipah, prefusion, paramyxovirus; HET: MAN, NAG, MLI, BMA; 3.367A {Nipah virus}
8507 Probab=45.38 E-value=18 Score=43.38 Aligned_cols=76 Identities=29% Similarity=0.344 Sum_probs=44.9 Template_Neff=4.700
8508
8509 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8510 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8511 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.+++. .-|.-...=|.|+.++++.++.++.|+.++||-+|.
8512 T Consensus 107 ~~RF~G~vig~vaLGVATaAqiTA~vAL~~a~~---na~~I~--~lk~si~~TN~AV~~l~~~~~~~~~Avq~iQd~IN~ 181 (529)
8513 T 5EVM_F 107 DVRLAGVIMAGVAIGIATAAQITAGVALYEAMK---NADNIN--KLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINT 181 (529)
8514 T ss_dssp ------EEEEHHHHCSEEHHHHHHHHHHHHHHH---HHHHHH--TTHHHHHHCCSSEEECCCSSSSCCEEEETTHHHCCC
8515 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8516 Confidence 345678888888899888888876554432110 001110 011112345788888888999999999999988876
8517
8518
8519 Q sp|P0DTC2|SPIK 955 N 955 (1273)
8520 Q Consensus 955 n 955 (1273)
8521 +
8522 T Consensus 182 ~ 182 (529)
8523 T 5EVM_F 182 N 182 (529)
8524 T ss_dssp C
8525 T ss_pred c
8526 Confidence 4
8527
8528
8529 No 101
8530 >6T3F_F Fusion glycoprotein F0, Fab66 light; Fusion Protein, Glycoprotein, Antibody, Fab; HET: NAG; 3.2A {Nipah virus}
8531 Probab=42.88 E-value=21 Score=42.66 Aligned_cols=76 Identities=29% Similarity=0.344 Sum_probs=49.9 Template_Neff=4.700
8532
8533 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8534 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8535 ..-++|.+..|-.+|.+.|.||--|..+.--.. -.+++. .-|.-...=|.|+.++++.++.++.|+.++||-+|.
8536 T Consensus 85 ~~Rf~G~iig~~ALGVAtaAqiTAgvAL~~a~~---na~~I~--~lk~si~~TN~AV~~l~~g~~~~~~Avq~iQd~IN~ 159 (502)
8537 T 6T3F_F 85 DVRLAGVIMAGVAIGIATAAQITAGVALYEAMK---NADNIN--KLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINT 159 (502)
8538 T ss_dssp CSSCCSCEECHHHHCSCCHHHHHHHHHHHHHHH---HHHHHH--TTHHHHHHCCSSEEEECSSSSSCEEEEETTHHHCCC
8539 T ss_pred ChhHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8540 Confidence 445678888888888888888876544321100 011111 011112345889999999999999999999999886
8541
8542
8543 Q sp|P0DTC2|SPIK 955 N 955 (1273)
8544 Q Consensus 955 n 955 (1273)
8545 +
8546 T Consensus 160 ~ 160 (502)
8547 T 6T3F_F 160 N 160 (502)
8548 T ss_dssp C
8549 T ss_pred c
8550 Confidence 4
8551
8552
8553 No 102
8554 >3N27_B Fusion glycoprotein F0, linker, Fusion; Fusion protein, Chimera protein, fusion; HET: CIT, TBU; 1.8A {Hendravirus, Nipahvirus}
8555 Probab=42.74 E-value=21 Score=34.63 Aligned_cols=28 Identities=32% Similarity=0.335 Sum_probs=18.2 Template_Neff=2.800
8556
8557 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8558 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8559 -|.|+.+++++++.++-|+.++||.+|.
8560 T Consensus 18 TNeAV~eL~~gl~q~avAIqaIQd~IN~ 45 (80)
8561 T 3N27_B 18 TNEAVVKLQETAEKTVYVLTALQDYSGG 45 (80)
8562 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHSSS
8563 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHhcC
8564 Confidence 3556666666666666666666666654
8565
8566
8567 No 103
8568 >1ZTM_C Fusion glycoprotein; fusion protein, 6-helix bundle,trimer, post-fusion; HET: NAG; 3.05A {Human parainfluenza virus 3}
8569 Probab=42.53 E-value=21 Score=42.44 Aligned_cols=75 Identities=20% Similarity=0.251 Sum_probs=29.7 Template_Neff=4.800
8570
8571 Q sp|P0DTC2|SPIK 876 ALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8572 Q Consensus 876 allagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8573 .-++|.|..|-.+|.+.|.||--|..+.-.- --.++++ .-|.-...=|.|+.++++.++.++.|+.++||-+|.+
8574 T Consensus 90 ~r~~g~iig~~algvataaqita~~al~~a~---~na~~i~--~lk~si~~tn~AV~~L~~g~~~~~~Avq~iQd~IN~~ 164 (490)
8575 T 1ZTM_C 90 KRFFGGVIGTIALGVATSAQITAAVALVEAK---QARSDIE--KLKEAIRDTNKAVQSVQSSIGNLIVAIKSVQDYVNKE 164 (490)
8576 T ss_dssp ----------------------------CCC---CCCSHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
8577 T ss_pred ccchhHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhc
8578 Confidence 3467778888888888888887654432110 0011111 1122223458899999999999999999999998864
8579
8580
8581 No 104
8582 >4GIP_D Fusion glycoprotein F2, Fusion glycoprotein; PIV5, viral fusion protein, membrane; HET: NAG; 2.0A {Simian virus 5}
8583 Probab=42.00 E-value=22 Score=41.54 Aligned_cols=72 Identities=22% Similarity=0.278 Sum_probs=47.3 Template_Neff=4.800
8584
8585 Q sp|P0DTC2|SPIK 878 LAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVL-YENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQN 955 (1273)
8586 Q Consensus 878 lagtitsgwtfgagaalqipfamqmayrfngigvtqnvl-yenqklianqfnsaigkiqdslsstasalgklqdvvnqn 955 (1273)
8587 ++|.+..|..+|.+.|.||--|..+.- ..||.- ...-|.-...=|.|+.++++.++.++.|+.++||-+|.+
8588 T Consensus 1 ~~g~~ig~~algvataaqita~~al~~------a~~na~~i~~lk~si~~tn~AV~~L~~g~~~~~~Av~~lQd~IN~~ 73 (409)
8589 T 4GIP_D 1 FAGVVIGLAALGVATAAQVTAAVALVK------ANENAAAILNLKNAIQKTNAAVADVVQATQSLGTAVQAVQDHINSV 73 (409)
8590 T ss_dssp CCSCEECGGGGCEEEHHHHHHHHHHHH------THHHHHHHHTTHHHHHHCCCSEEEEEETTEEEEEEECTTHHHHHHH
8591 T ss_pred CchHHHHHHHHHHHHHHHHHHHHHHHH------HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHc
8592 Confidence 467888888899888888876554321 111110 000111223457889999999999999999999988754
8593
8594
8595 No 105
8596 >6H2E_Q AhlB; Tripartite pore-forming toxin, TOXIN; 2.35A {Aeromonas hydrophila}
8597 Probab=41.72 E-value=22 Score=35.49 Aligned_cols=23 Identities=22% Similarity=0.426 Sum_probs=11.9 Template_Neff=9.500
8598
8599 Q sp|P0DTC2|SPIK 1173 NASVVNIQKEIDRLNEVAKNLNE 1195 (1273)
8600 Q Consensus 1173 nasvvniqkeidrlnevaknlne 1195 (1273)
8601 +..+..++++|++|++-.+.++.
8602 T Consensus 128 ~~~i~~l~~~I~~l~~~i~~~~~ 150 (274)
8603 T 6H2E_Q 128 QATIAGLQSNLDGARQELDSLNK 150 (274)
8604 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHH
8605 T ss_pred HHHHHHHHHHHHHHHHHHHHHHH
8606 Confidence 34445555556555555544444
8607
8608
8609 No 106
8610 >5IJO_G Nuclear pore complex protein Nup155; Nuclear pore complex, Nucleocytoplasmic transport; 21.4A {Homo sapiens}
8611 Probab=40.35 E-value=24 Score=42.67 Aligned_cols=55 Identities=18% Similarity=0.345 Sum_probs=33.8 Template_Neff=5.300
8612
8613 Q sp|P0DTC2|SPIK 1133 VNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEV 1189 (1273)
8614 Q Consensus 1133 vnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnev 1189 (1273)
8615 ..++-|+.|.+|+....|+||||+|....-.-++...+. ..+.+|+++|++|...
8616 T Consensus 239 sk~~K~~dLP~eIqk~VE~LdkfIK~QkqisdEIsr~Ss--~~l~kV~~DIe~L~q~ 293 (599)
8617 T 5IJO_G 239 SKALKDENLPPVICQDVENLQKFVKEQKQVQEEISRMSS--KAMLKVQEDIKALKQL 293 (599)
8618 T ss_dssp ---------CHHHHHHHHHHHHHHHHHHHHHHHHHHHCC--SHHHHHHHHHHHHHHH
8619 T ss_pred chhhhhccCCHHHHHHHHHHHHHHHHHHHHHHHHHhcCH--HHHHHHHHHHHHHHHH
8620 Confidence 346778888889988899999999988776666665553 3466777777766543
8621
8622
8623 No 107
8624 >1WP7_A fusion protein; Nipah Virus, Fusion Core, heptad; 2.2A {Nipah virus}
8625 Probab=40.33 E-value=24 Score=34.77 Aligned_cols=28 Identities=32% Similarity=0.322 Sum_probs=18.7 Template_Neff=2.700
8626
8627 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8628 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8629 -|.|+.+++++++.++-|+.++||-+|.
8630 T Consensus 18 TNeAV~eL~~gl~qtavAIqaIQD~IN~ 45 (89)
8631 T 1WP7_A 18 TNEAVVKLQETAEKTVYVLTALQDYGGS 45 (89)
8632 T ss_dssp HHHHHHHHHHHHHHHHHHHHHCCC----
8633 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHccC
8634 Confidence 4677777888888888888888877763
8635
8636
8637 No 108
8638 >1WP8_C fusion; Hendra Virus, Fusion Core, heptad; 2.2A {Hendra virus}
8639 Probab=39.60 E-value=25 Score=34.65 Aligned_cols=28 Identities=32% Similarity=0.322 Sum_probs=18.4 Template_Neff=2.700
8640
8641 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8642 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8643 -|.|+.+++++++.++-|+.++||-+|.
8644 T Consensus 18 TNeAV~eL~~gl~qtavAIqaIQD~IN~ 45 (89)
8645 T 1WP8_C 18 TNEAVVKLQETAEKTVYVLTALQDYGGS 45 (89)
8646 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHTC----
8647 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHccC
8648 Confidence 4667777777777777777777777763
8649
8650
8651 No 109
8652 >6R1J_J AhlB; Tripartite pore-forming toxin, TOXIN; 1.92A {Aeromonas hydrophila J-1}
8653 Probab=39.16 E-value=26 Score=34.77 Aligned_cols=24 Identities=21% Similarity=0.447 Sum_probs=12.5 Template_Neff=9.700
8654
8655 Q sp|P0DTC2|SPIK 1172 INASVVNIQKEIDRLNEVAKNLNE 1195 (1273)
8656 Q Consensus 1172 inasvvniqkeidrlnevaknlne 1195 (1273)
8657 ++..+..++++|+.|++-.+.++.
8658 T Consensus 127 ~~~~i~~l~~~I~~l~~~I~~~~~ 150 (272)
8659 T 6R1J_J 127 LQATIAGLQSNLDGARQELDSLNK 150 (272)
8660 T ss_pred chHhHHHHHHHHHHHHHHHHHHHH
8661 Confidence 344445555566655555554444
8662
8663
8664 No 110
8665 >6C14_A Protocadherin-15, LHFPL tetraspan subfamily member; PCDH15, LHFPL5, protocadherin, tip link;{Mus musculus}
8666 Probab=38.64 E-value=27 Score=35.39 Aligned_cols=26 Identities=35% Similarity=0.680 Sum_probs=13.7 Template_Neff=10.000
8667
8668 Q sp|P0DTC2|SPIK 1108 NFYEPQIITTDNT--FVSGNCDVVIGIV 1133 (1273)
8669 Q Consensus 1108 nfyepqiittdnt--fvsgncdvvigiv 1133 (1273)
8670 ..|+-.+..+|+. -.+..+.|.|-++
8671 T Consensus 82 ~~~~l~V~A~D~~~~~~~~~~~v~I~V~ 109 (337)
8672 T 6C14_A 82 SYFKFQVIATDDYGKGLSGKADVLVSVV 109 (337)
8673 T ss_dssp CCEEEEEEEEHHHHTSCEEEEEEEECEE
8674 T ss_pred CeEEEEEEEEcCCCCCCCeEEEEEEEEe
8675 Confidence 4556666667764 2334455555443
8676
8677
8678 No 111
8679 >5EJB_D Fusion glycoprotein F0; prefusion form, viral glycoprotein, ectodomain; HET: NAG, SO4; 3.2A {Hendra virus}
8680 Probab=38.02 E-value=28 Score=41.68 Aligned_cols=76 Identities=28% Similarity=0.344 Sum_probs=45.1 Template_Neff=4.700
8681
8682 Q sp|P0DTC2|SPIK 875 SALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQ 954 (1273)
8683 Q Consensus 875 sallagtitsgwtfgagaalqipfamqmayrfngigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnq 954 (1273)
8684 ..-++|.+..|..+|.+.|.||--|..+.--.. -.+++. .-|.-...=|.|+.++++.++.++.|+.++||-+|.
8685 T Consensus 82 ~~Rf~G~iig~~AlgVAtaaqita~vAl~~a~~---na~~i~--~lk~si~~tn~AV~~L~~g~~~~~~Avq~lQd~IN~ 156 (501)
8686 T 5EJB_D 82 DVKLAGVVMAGIAIGIATAAQITAGVALYEAMK---NADNIN--KLKSSIESTNEAVVKLQETAEKTVYVLTALQDYINT 156 (501)
8687 T ss_dssp -------CEEHHHHCSEEHHHHHHHHHHHHHHH---HHHHHH--TTHHHHHTCCSSEEEEECSSSCEEEEEETTHHHCCC
8688 T ss_pred CcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHH---HHHHHH--HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8689 Confidence 345678888888888888888765543321100 001111 011112345889999999999999999999999886
8690
8691
8692 Q sp|P0DTC2|SPIK 955 N 955 (1273)
8693 Q Consensus 955 n 955 (1273)
8694 +
8695 T Consensus 157 ~ 157 (501)
8696 T 5EJB_D 157 N 157 (501)
8697 T ss_dssp C
8698 T ss_pred c
8699 Confidence 4
8700
8701
8702 No 112
8703 >2M8R_A Syntaxin-1A; syntaxin, SNARE, Prefusion, membrane protein; NMR {Rattus norvegicus}
8704 Probab=36.65 E-value=30 Score=29.72 Aligned_cols=12 Identities=8% Similarity=0.033 Sum_probs=5.6 Template_Neff=9.700
8705
8706 Q sp|P0DTC2|SPIK 1211 KWPWYIWLGFIA 1222 (1273)
8707 Q Consensus 1211 kwpwyiwlgfia 1222 (1273)
8708 +|-|++.+++++
8709 T Consensus 84 ~~~~~~~~~~~~ 95 (109)
8710 T 2M8R_A 84 RKKIMIIICCVI 95 (109)
8711 T ss_dssp HHHHHHHHHHHH
8712 T ss_pred HHHHHHHHHHHH
8713 Confidence 355555444333
8714
8715
8716 No 113
8717 >3HD7_B Vesicle-associated membrane protein 2, Syntaxin-1A; MEMBRANE PROTEIN, COILED-COIL, 4-HELICAL BUNDLE; HET: SO4, GGG; 3.4A {Rattus norvegicus}
8718 Probab=36.65 E-value=30 Score=29.72 Aligned_cols=12 Identities=8% Similarity=0.033 Sum_probs=5.6 Template_Neff=9.700
8719
8720 Q sp|P0DTC2|SPIK 1211 KWPWYIWLGFIA 1222 (1273)
8721 Q Consensus 1211 kwpwyiwlgfia 1222 (1273)
8722 +|-|++.+++++
8723 T Consensus 84 ~~~~~~~~~~~~ 95 (109)
8724 T 3HD7_B 84 RKKIMIIICCVI 95 (109)
8725 T ss_dssp HHHHHHHHHHHH
8726 T ss_pred HHHHHHHHHHHH
8727 Confidence 355555444333
8728
8729
8730 No 114
8731 >5C3L_B Nucleoporin Nup54, MGC84997 protein, Nucleoporin; nucleoporin, heterotrimeric coiled coils, kink; 2.9A {Xenopus laevis}
8732 Probab=34.34 E-value=35 Score=32.07 Aligned_cols=57 Identities=16% Similarity=0.251 Sum_probs=31.9 Template_Neff=8.500
8733
8734 Q sp|P0DTC2|SPIK 1131 GIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEV 1189 (1273)
8735 Q Consensus 1131 givnntvydplqpeldsfkeeldkyfknhtspdvdlgdisginasvvniqkeidrlnev 1189 (1273)
8736 ++--+|-|+.|.|++....++|+++++....-.-++...+- ..+..+..++++|..-
8737 T Consensus 6 ~~~~~tkf~dLp~~~q~~l~~ld~~I~~q~~~~~el~~~~~--~~~~~i~~di~~l~~~ 62 (142)
8738 T 5C3L_B 6 EDSKALKDENLPQLLCQDVENFQKFVKEQKQVQEEISRMSS--KAMLKVQEDIKALKQL 62 (142)
8739 T ss_dssp ------------CCSGGGGGGGTHHHHHHHHHHHHHHHCCS--HHHHHHHHHHHHHHHH
8740 T ss_pred ccccccccccCCHHHHHHHHHHHHHHHHHHHHHHHHHhhch--HHHHHHHHHHHHHHHH
8741 Confidence 34557889999999999999999999987766655555443 3566666666655443
8742
8743
8744 No 115
8745 >5G6U_A LANGERIN; CARBOHYDRATE BINDING PROTEIN, LANGERIN, CD207; HET: TRP, CL, YJM; 1.844A {HOMO SAPIENS}
8746 Probab=32.97 E-value=38 Score=33.48 Aligned_cols=42 Identities=17% Similarity=0.467 Sum_probs=25.7 Template_Neff=9.700
8747
8748 Q sp|P0DTC2|SPIK 1038 KRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFP 1090 (1273)
8749 Q Consensus 1038 krvdfcgkgyhlmsfpqsaphgvvflhvtyvpaqeknfttapaichdgkahfp 1090 (1273)
8750 .....|..||.... |..| |+....++|..|-..|.+-.+|..
8751 T Consensus 123 ~~~~~c~~~w~~~~-------~~cy----~~~~~~~tw~~A~~~C~~~g~~L~ 164 (261)
8752 T 5G6U_A 123 DILQVVSQGWKYFK-------GNFY----YFSLIPKTWYSAEQFCVSRNSHLT 164 (261)
8753 T ss_pred cccccCCCCeEEEC-------CEEE----EEEeceeCHHHHHHHHHHcCCEee
8754 Confidence 44567877776531 2211 222346788899999988766654
8755
8756
8757 No 116
8758 >3IPD_E Vesicle-associated membrane protein 2, Syntaxin-1A; MEMBRANE PROTEIN, COILED COIL, 4-HELICAL; 4.8A {Rattus norvegicus}
8759 Probab=26.85 E-value=56 Score=28.69 Aligned_cols=9 Identities=33% Similarity=0.386 Sum_probs=3.8 Template_Neff=8.400
8760
8761 Q sp|P0DTC2|SPIK 1212 WPWYIWLGF 1220 (1273)
8762 Q Consensus 1212 wpwyiwlgf 1220 (1273)
8763 +-|++.+++
8764 T Consensus 68 ~k~~iii~~ 76 (91)
8765 T 3IPD_E 68 LKMMIILGV 76 (91)
8766 T ss_dssp HHHHHTTTT
8767 T ss_pred HHHHHHHHH
8768 Confidence 344444443
8769
8770
8771 No 117
8772 >3HD7_A Vesicle-associated membrane protein 2, Syntaxin-1A; MEMBRANE PROTEIN, COILED-COIL, 4-HELICAL BUNDLE; HET: SO4, GGG; 3.4A {Rattus norvegicus}
8773 Probab=26.85 E-value=56 Score=28.69 Aligned_cols=9 Identities=33% Similarity=0.386 Sum_probs=3.8 Template_Neff=8.400
8774
8775 Q sp|P0DTC2|SPIK 1212 WPWYIWLGF 1220 (1273)
8776 Q Consensus 1212 wpwyiwlgf 1220 (1273)
8777 +-|++.+++
8778 T Consensus 68 ~k~~iii~~ 76 (91)
8779 T 3HD7_A 68 LKMMIILGV 76 (91)
8780 T ss_dssp HHHHHHHHH
8781 T ss_pred HHHHHHHHH
8782 Confidence 344444443
8783
8784
8785 No 118
8786 >6BP2_B Envelope Glycoprotein GP1, Envelope Glycoprotein; Marburg, Ravn, Glycoprotein, Complex, VIRAL; HET: NAG, BMA, MAN; 3.172A {Marburg marburgvirus}
8787 Probab=24.89 E-value=64 Score=35.25 Aligned_cols=40 Identities=13% Similarity=0.088 Sum_probs=26.5 Template_Neff=4.200
8788
8789 Q sp|P0DTC2|SPIK 925 NQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
8790 Q Consensus 925 nqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
8791 .+....+....++++.....+..+..+|-||..||.-|.-
8792 T Consensus 122 ~~l~k~~N~Ts~ALs~L~~ql~SLr~vvLQNR~ALD~LLa 161 (202)
8793 T 6BP2_B 122 CRLRRLANQTAKSLELLLRVTTEERTFSLINRHAIDFLLT 161 (202)
8794 T ss_dssp HHHHHHHHHHHHHHHHHHHHCCCCSCCCHHHHHHHHHHHH
8795 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHhHHHH
8796 Confidence 3334444445555556666666678899999999987654
8797
8798
8799 No 119
8800 >6QD8_D Light chain, Virion spike glycoprotein,EBOV-GP1; Antibody, immune response, viral infection; HET: NAG, BMA;{Homo sapiens}
8801 Probab=23.45 E-value=72 Score=33.90 Aligned_cols=34 Identities=18% Similarity=0.191 Sum_probs=21.5 Template_Neff=4.700
8802
8803 Q sp|P0DTC2|SPIK 931 IGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
8804 Q Consensus 931 igkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
8805 +....++++.....+..+..+|-||..||.-|.-
8806 T Consensus 61 ~N~T~~aL~~L~~ql~Slr~vvLQNR~ALD~Ll~ 94 (168)
8807 T 6QD8_D 61 ANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (168)
8808 T ss_dssp HHHHHHHHHHHHHHCCCSEECCHHHHHHHHHHHH
8809 T ss_pred HHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
8810 Confidence 3334444444445555567788999999887643
8811
8812
8813 No 120
8814 >4NJL_A S protein; six-helix-bundle, coronavirus, MERS-Cov, fusion inhibitor; HET: PGE; 2.3A {Middle East respiratory syndrome coronavirus}
8815 Probab=22.64 E-value=76 Score=33.23 Aligned_cols=27 Identities=52% Similarity=0.736 Sum_probs=14.8 Template_Neff=2.500
8816
8817 Q sp|P0DTC2|SPIK 1178 NIQKEIDRLNEVAKNLNESLIDLQELG 1204 (1273)
8818 Q Consensus 1178 niqkeidrlnevaknlneslidlqelg 1204 (1273)
8819 .+--|.-.+..+.|.+||+.|||.|||
8820 T Consensus 104 d~t~~~~s~~q~~~~~ne~~~~~~~~~ 130 (131)
8821 T 4NJL_A 104 DLTYEMLSLQQVVKALNESYIDLKELG 130 (131)
8822 T ss_dssp CCHHHHHHHHHHHHHHHTTCCCGGGSC
8823 T ss_pred HHHHHHhhHHHHHHHHHHhcccHHHhc
8824 Confidence 333333444555566666666666665
8825
8826
8827 No 121
8828 >4LWS_B Uncharacterized protein; ESX Secretion, Signal Sequence, Type; HET: ACT, GOL; 2.0A {Thermomonospora curvata}
8829 Probab=22.18 E-value=79 Score=26.31 Aligned_cols=32 Identities=9% Similarity=0.094 Sum_probs=19.5 Template_Neff=10.300
8830
8831 Q sp|P0DTC2|SPIK 955 NAQALNTLVKQLSSNFGAISSVLNDILSRLDK 986 (1273)
8832 Q Consensus 955 naqalntlvkqlssnfgaissvlndilsrldk 986 (1273)
8833 .++++..+.+++...+..+...|+++-..|..
8834 T Consensus 54 a~~~~~~~~~~~~~~~~~~~~~l~~~~~~l~~ 85 (103)
8835 T 4LWS_B 54 AQAAYWNYQKEWDAAAKDMQNVVAQLGVAIRE 85 (103)
8836 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8837 Confidence 45556666666666666666666666555544
8838
8839
8840 No 122
8841 >2NRJ_A Hbl B protein; Enterotoxin Hemolysis Transmembrane; 2.03A {Bacillus cereus} SCOP: h.4.4.2
8842 Probab=21.90 E-value=80 Score=32.38 Aligned_cols=15 Identities=20% Similarity=0.202 Sum_probs=6.3 Template_Neff=9.900
8843
8844 Q sp|P0DTC2|SPIK 1205 KYEQYIKWPWYIWLG 1219 (1273)
8845 Q Consensus 1205 kyeqyikwpwyiwlg 1219 (1273)
8846 +|+.++..-|++++|
8847 T Consensus 194 ~~~~~~~~~~~~~~g 208 (346)
8848 T 2NRJ_A 194 YYKQLESDGFNVMKG 208 (346)
8849 T ss_dssp GGGCCC--CCGGGTS
8850 T ss_pred HHHHHhhccchhchH
8851 Confidence 455554444544444
8852
8853
8854 No 123
8855 >2N2A_B Receptor tyrosine-protein kinase erbB-2; HER2, ErbB2, Tyrosine kinase, Activation; NMR {Homo sapiens}
8856 Probab=21.75 E-value=81 Score=26.93 Aligned_cols=23 Identities=22% Similarity=0.033 Sum_probs=13.7 Template_Neff=7.000
8857
8858 Q sp|P0DTC2|SPIK 1206 YEQYIKWPWYIWLGFIAGLIAIV 1228 (1273)
8859 Q Consensus 1206 yeqyikwpwyiwlgfiagliaiv 1228 (1273)
8860 |||-.+-...|+.|.++|+++++
8861 T Consensus 1 ~~~~~~~~~~I~~~Vvg~l~~~~ 23 (58)
8862 T 2N2A_B 1 AEQRASPLTSIISAVVGILLVVV 23 (58)
8863 T ss_dssp CCCCCCHHHHHHHHHHHHHHHHH
8864 T ss_pred CCcccCChHHHHHHHHHHHHHHH
8865 Confidence 34555545557777777776443
8866
8867
8868 No 124
8869 >6F5U_B Envelope glycoprotein,GP1, Envelope glycoprotein; EBOLA VIRUS, FILOVIRIDAE, ENVELOPE GLYCOPROTEIN; HET: NAG, GOL, CQN, DMS, BMA, MAN; 2.07A {Zaire ebolavirus (strain Mayinga-76)}
8870 Probab=21.41 E-value=83 Score=33.10 Aligned_cols=38 Identities=16% Similarity=0.183 Sum_probs=24.4 Template_Neff=5.300
8871
8872 Q sp|P0DTC2|SPIK 927 FNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
8873 Q Consensus 927 fnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
8874 ....+....++++.....+..+..+|-||..||.-|.-
8875 T Consensus 57 l~~~~n~T~~al~~L~~~l~slr~vvLQNR~aLD~Ll~ 94 (168)
8876 T 6F5U_B 57 LRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (168)
8877 T ss_dssp HHHHHHHHHHHHHHHHHHCCCSEECCHHHHHHHHHHHH
8878 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
8879 Confidence 33334444555555555556677889999999887653
8880
8881
8882 No 125
8883 >5F1B_B GP1, GP2, Niemann-Pick C1 protein; Ebola virus, glycoprotein, NPC1-C, VIRAL; HET: NAG; 2.3A {Zaire ebolavirus}
8884 Probab=21.40 E-value=84 Score=31.95 Aligned_cols=37 Identities=16% Similarity=0.180 Sum_probs=24.1 Template_Neff=5.300
8885
8886 Q sp|P0DTC2|SPIK 929 SAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQ 965 (1273)
8887 Q Consensus 929 saigkiqdslsstasalgklqdvvnqnaqalntlvkq 965 (1273)
8888 ..+....++++.....+..+..+|-||..||.-|.-+
8889 T Consensus 52 ~~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Ll~~ 88 (130)
8890 T 5F1B_B 52 QLANETTQALQLFLRATTELRTFSILNRKAIDFLLQR 88 (130)
8891 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHhhhHHHHHHHHHh
8892 Confidence 3344445555555555666778889999998876543
8893
8894
8895 No 126
8896 >6HS4_B Envelope glycoprotein,Envelope glycoprotein,Envelope glycoprotein, Envelope; Ebola Glycoprotein, Structure-based In Silico; HET: BMA, GON, NAG, GOL, MAN; 2.05A {Zaire ebolavirus (strain Mayinga-76)}
8897 Probab=21.34 E-value=84 Score=33.08 Aligned_cols=40 Identities=15% Similarity=0.150 Sum_probs=25.9 Template_Neff=5.300
8898
8899 Q sp|P0DTC2|SPIK 925 NQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
8900 Q Consensus 925 nqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
8901 .+....+....++++.....+..+..+|-||..||.-|.-
8902 T Consensus 55 ~~l~~~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Ll~ 94 (168)
8903 T 6HS4_B 55 CGLRQLANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (168)
8904 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
8905 Confidence 3333444445555555566666677889999999987653
8906
8907
8908 No 127
8909 >2KG7_A Uncharacterized protein esxG (PE family; Protein complex, UNKNOWN FUNCTION; NMR {Mycobacterium tuberculosis}
8910 Probab=21.11 E-value=85 Score=25.82 Aligned_cols=66 Identities=11% Similarity=0.201 Sum_probs=38.0 Template_Neff=10.300
8911
8912 Q sp|P0DTC2|SPIK 923 IANQFNSAIGKIQDSLSSTASALGKLQDVVN-QNAQALNTLVKQLSSNFGAISSVLNDILSRLDKVE 988 (1273)
8913 Q Consensus 923 ianqfnsaigkiqdslsstasalgklqdvvn-qnaqalntlvkqlssnfgaissvlndilsrldkve 988 (1273)
8914 .++++.+..+.|++.++.....+..|...-. ..+.+......++...+..+...|+++-..|.+..
8915 T Consensus 14 ~a~~~~~~~~~l~~~~~~l~~~~~~l~~~W~G~a~~af~~~~~~~~~~~~~~~~~L~~~~~~l~~~~ 80 (97)
8916 T 2KG7_A 14 SQSAFAAKAGLMRHTIGQAEQAAMSAQAFHQGESSAAFQAAHARFVAAAAKVNTLLDVAQANLGEAA 80 (97)
8917 T ss_dssp TTCHHHHHHHHHHHHHHHHHHHHHHHGGGTCSSCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHSTTC
8918 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHhhcchHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8919 Confidence 4555666666666666555555554432222 23445666666666666666666666666665543
8920
8921
8922 No 128
8923 >6W08_B NSP15 endoribnuclease; Tripartite pore forming toxin, Cytotoxin; HET: EDO; 1.75A {Vibrio cholerae O1 biovar El Tor str. N16961}
8924 Probab=20.88 E-value=87 Score=32.75 Aligned_cols=55 Identities=15% Similarity=0.317 Sum_probs=27.7 Template_Neff=9.500
8925
8926 Q sp|P0DTC2|SPIK 1139 DPLQPELDSFKEELDKYFKNHTSPDVDLGD--------ISGINASVVNIQKEIDRLNEVAKNL 1193 (1273)
8927 Q Consensus 1139 dplqpeldsfkeeldkyfknhtspdvdlgd--------isginasvvniqkeidrlnevaknl 1193 (1273)
8928 +.++.+++.|+..|..+...-..-.-++.. ..+.++.+..++++|++|++-.+.+
8929 T Consensus 122 ~~~~~~~~~~~~~l~~f~~~~~~~~~~l~~~~~~~~~~~~~~~~~i~~L~~~I~~l~~~i~~~ 184 (359)
8930 T 6W08_B 122 QSLTSNIKRYDEGLNAWARQVEDAHNTLQQTIAQIQQEEVSIQAEIIATNAQIDLMKQQIAAF 184 (359)
8931 T ss_dssp HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCGGGHHHHHHHHHHHHHHHHHHHHH
8932 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8933 Confidence 456666667777666554442222222322 1334445556666666665544433
8934
8935
8936 No 129
8937 >3OGI_C Putative ESAT-6-like protein 6, Putative; Structural Genomics, PSI-2, Protein Structure; HET: MSE; 2.549A {Mycobacterium tuberculosis}
8938 Probab=20.43 E-value=90 Score=26.79 Aligned_cols=66 Identities=14% Similarity=0.137 Sum_probs=31.7 Template_Neff=9.500
8939
8940 Q sp|P0DTC2|SPIK 921 KLIANQFNSAIGKIQDSLSSTASALGKLQDV-VNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDK 986 (1273)
8941 Q Consensus 921 klianqfnsaigkiqdslsstasalgklqdv-vnqnaqalntlvkqlssnfgaissvlndilsrldk 986 (1273)
8942 .-.++.+....+.|++.++.....+..|.+. ....+++......++...+..+...|+++-..|+.
8943 T Consensus 11 ~~~a~~l~~~~~~l~~~~~~l~~~~~~l~~~W~G~a~~af~~~~~~~~~~~~~~~~~l~~~~~~l~~ 77 (101)
8944 T 3OGI_C 11 DAHGAMIRAQAGLLEAEHQAIVRDVLAAGDFWGGAGSVACQEFITQLGRNFQVIYEQANAHGQKVQA 77 (101)
8945 T ss_dssp --CHHHHHHHHHHHHHHHHHHHHHHHHTGGGTTCTTSHHHHHHHHHHHHHHHHHTTCC---------
8946 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhccHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
8947 Confidence 3455666666666666666555555555332 22345555566666666666666666666555544
8948
8949
8950 No 130
8951 >5HJ3_L Envelope glycoprotein, KZ52 Antibody Fragment; Ebola virus, EOV, Ebolavirus, GP; HET: MAN, NAG, BMA; 3.3A {Ebola virus sp.}
8952 Probab=20.10 E-value=93 Score=31.85 Aligned_cols=35 Identities=17% Similarity=0.174 Sum_probs=23.0 Template_Neff=5.300
8953
8954 Q sp|P0DTC2|SPIK 930 AIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
8955 Q Consensus 930 aigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
8956 .+....++++.....+..+..+|-||..||.-|.-
8957 T Consensus 60 ~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Lla 94 (136)
8958 T 5HJ3_L 60 LANETTQALQLFLRATTELRTFSILNRKAIDFLLQ 94 (136)
8959 T ss_pred HHHHHHHHHHHHHHHHHHHHHHHhhchHHHHHHHH
8960 Confidence 33444455555555566677888999999887653
8961
8962
8963 No 131
8964 >6RX1_A Syncytin-1; HUMAN PLACENTAL PROTEIN, MEMBRANE FUSION; 2.1A {Homo sapiens}
8965 Probab=20.03 E-value=93 Score=30.99 Aligned_cols=53 Identities=26% Similarity=0.386 Sum_probs=30.7 Template_Neff=5.000
8966
8967 Q sp|P0DTC2|SPIK 908 GIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVK 964 (1273)
8968 Q Consensus 908 gigvtqnvlyenqklianqfnsaigkiqdslsstasalgklqdvvnqnaqalntlvk 964 (1273)
8969 |.|+++.-+. .+..+....+....++++.....+..+..+|-||..||.-|.-
8970 T Consensus 12 ~~~~~~~~l~----~L~~~l~~~~n~t~~al~~L~~~l~sl~~vvLQNR~aLD~Ll~ 64 (108)
8971 T 6RX1_A 12 FQSTSTQFYY----KLSQELNGDMERVADSLVTLQDQLNSLAAVVLQNRRALDLLTA 64 (108)
8972 T ss_dssp ------CHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHTG
8973 T ss_pred ccchhhHHHH----HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHhhchhHHHHHHH
8974 Confidence 5555553222 2333444445556666777777777788899999999887653
8975
8976