Mercurial > repos > iuc > cnvkit_scatter
diff scatter.xml @ 5:64960243c9e1 draft default tip
planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/cnvkit commit fc1282ec68b346988203ead860e9b9d6a47e9efb
author | iuc |
---|---|
date | Sat, 01 Mar 2025 12:04:46 +0000 |
parents | 02446206f574 |
children |
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--- a/scatter.xml Mon Jan 20 16:40:44 2025 +0000 +++ b/scatter.xml Sat Mar 01 12:04:46 2025 +0000 @@ -72,7 +72,7 @@ #end if ]]></command> <inputs> - <param name="input_cnr_file" type="data" format="tabular" label="Bin-Level log2 Ratios/Coverages cnr file" help="" /> + <param name="input_cnr_file" type="data" format="cnr" label="Bin-Level log2 Ratios/Coverages cnr file" help="" /> <section name="advanced_settings" title="Advanced settings" expanded="false"> <expand macro="scatter_optional" /> <section name="plot_aesthetics" title="Plot aesthetics" expanded="false"> @@ -88,7 +88,7 @@ </outputs> <tests> <test expect_num_outputs="1"> - <param name="input_cnr_file" ftype="tabular" value="tumor.cnr" /> + <param name="input_cnr_file" ftype="cnr" value="tumor.cnr" /> <section name="advanced_settings"> <section name="additional_SNP_allelic_process"> <param name="zygosity_freq" value="0.25" /> @@ -105,6 +105,41 @@ <help><![CDATA[ Plot bin-level log2 coverages and segmentation calls together. Without any further arguments, this plots the genome-wide copy number in a form familiar to those who have used array CGH. + +----- + +**Bin-level log2 ratios (.cnr)** + +Tabular file containing normalized log2 ratios for small genomic bins (divided regions of the genome). Used to detect raw copy number variations (CNVs) before segmentation. + +.. csv-table:: + :header-rows: 0 + + "chromosome","Genomic chromosome (e.g., chr1, chrX)" + "start","Start position of the bin." + "end","End position of the bin." + "gene","Gene name(s) overlapping the bin (if applicable)." + "log2","Normalized log2 ratio (sample coverage / reference coverage)." + "depth","Average read depth in the bin." + "weight","Reliability weight of the bin (higher = more reliable)." + +----- + +**Segmented log2 ratios (.cns)** + +Tabular file with smoothed, merged segments of stable copy number, derived from the .cnr file. Represents final CNV calls. + +.. csv-table:: + :header-rows: 0 + + "chromosome","start, end: Genomic coordinates of the segment" + "gene","Gene(s) overlapping the segment." + "log2","Mean log2 ratio of the segment." + "probes","Mean log2 ratio of the segment." + "depth","Average read depth." + "weight","Reliability weight." + "p_value","Statistical confidence (lower = more significant)." + ]]></help> <expand macro="citations" /> </tool>