Mercurial > repos > iuc > cnvkit_segment
diff segment.xml @ 5:bdd0e8e05933 draft default tip
planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/cnvkit commit fc1282ec68b346988203ead860e9b9d6a47e9efb
author | iuc |
---|---|
date | Sat, 01 Mar 2025 12:06:19 +0000 |
parents | 33be231ce128 |
children |
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--- a/segment.xml Mon Jan 20 16:37:32 2025 +0000 +++ b/segment.xml Sat Mar 01 12:06:19 2025 +0000 @@ -50,7 +50,7 @@ #end if ]]></command> <inputs> - <param name="filename" type="data" format="tabular" label="Bin-Level log2 Ratios/Coverages cnr file" help="Use the output of the CNVkit fix" /> + <param name="filename" type="data" format="cnr" label="Bin-Level log2 Ratios/Coverages cnr file" help="Use the output of the CNVkit fix" /> <section name="additional_SNP_allelic_process" title="additional process for SNP b_allele frequencies" expanded="false"> <expand macro="additionally_SNP_process" /> </section> @@ -59,11 +59,11 @@ </section> </inputs> <outputs> - <data name="out_sample_segment" format="tabular" label="${tool.name} on ${on_string}: Sample segment" from_work_dir="sample.cns" /> + <data name="out_sample_segment" format="cns" label="${tool.name} on ${on_string}: Sample segment" from_work_dir="sample.cns" /> </outputs> <tests> <test expect_num_outputs="1"> - <param name="filename" ftype="tabular" value="tumor.cnr" /> + <param name="filename" ftype="cnr" value="tumor.cnr" /> <section name="advanced_settings"> <param name="method" value="hmm" /> <param name="threshold" value="2" /> @@ -81,6 +81,41 @@ Segmented log2 ratios (.cns) output file contains those columns chromosome, Start, end, gene, log2, depth, weight and number of bins covered by the segment (probes) + +----- + +**Bin-level log2 ratios (.cnr)** + +Tabular file containing normalized log2 ratios for small genomic bins (divided regions of the genome). Used to detect raw copy number variations (CNVs) before segmentation. + +.. csv-table:: + :header-rows: 0 + + "chromosome","Genomic chromosome (e.g., chr1, chrX)" + "start","Start position of the bin." + "end","End position of the bin." + "gene","Gene name(s) overlapping the bin (if applicable)." + "log2","Normalized log2 ratio (sample coverage / reference coverage)." + "depth","Average read depth in the bin." + "weight","Reliability weight of the bin (higher = more reliable)." + +----- + +**Segmented log2 ratios (.cns)** + +Tabular file with smoothed, merged segments of stable copy number, derived from the .cnr file. Represents final CNV calls. + +.. csv-table:: + :header-rows: 0 + + "chromosome","start, end: Genomic coordinates of the segment" + "gene","Gene(s) overlapping the segment." + "log2","Mean log2 ratio of the segment." + "probes","Mean log2 ratio of the segment." + "depth","Average read depth." + "weight","Reliability weight." + "p_value","Statistical confidence (lower = more significant)." + ]]></help> <expand macro="citations" /> </tool>