--- a/samples_macros.xml	Fri Oct 27 19:44:40 2023 +0000
+++ b/samples_macros.xml	Sat Mar 23 22:06:45 2024 +0000
@@ -1,6 +1,6 @@
 <macros>
     <xml name="checklist_input_macro">
-        <param type="select" name="checklist_id" label="Select the metadata checklist" help="You can find metadata templates for each checklist at: https://github.com/ELIXIR-Belgium/ENA-metadata-templates">
+        <param type="select" name="checklist_id" label="Select the ENA sample checklist" help="You can find metadata templates for each checklist at: https://github.com/ELIXIR-Belgium/ENA-metadata-templates">
             <option value="ERC000011">ENA default sample checklist (ERC000011)</option>
             <option value="ERC000012">GSC MIxS air (ERC000012)</option>
             <option value="ERC000013">GSC MIxS host associated (ERC000013)</option>
@@ -44,37 +44,39 @@
         </param>
     </xml>
     <xml name="test_submit_section">
-        <section name="test_submit_parameters" expanded="True" title="Testing options">
-            <param name="submit_dev" type="boolean" truevalue="True" falsevalue="False" label="Submit to test ENA server?" help="By selecting yes the reads will be submitted to the ENA test server. Uploads to test platform will not be public and will be removed in 24hrs. Performing a preliminary test upload is advised to check for errors with metadata structure. You can find the uploads to the test platform at https://wwwdev.ebi.ac.uk/ena/" />
-            <param name="dry_run" type="boolean" truevalue="True" falsevalue="False" label="Print the tables but do not submit the datasets" help="If yes is selected then NO submission will be performed."/>
+        <section name="test_submit_parameters" expanded="True" title="Submissions options">
+            <param name="center" type="text" optional="False" label="Affiliation center"/>
+            <param name="submit_dev" type="boolean" truevalue="True" falsevalue="False" label="Submit to ENA test server" help="Uploads to the test server of ENA will not be made public and will be removed automatically in 24 hours. Performing a preliminary test upload is advised to check for errors with metadata structure. You can find these uploads at https://wwwdev.ebi.ac.uk/ena/." />
+            <param name="dry_run" type="boolean" truevalue="True" falsevalue="False" label="Create test outputs without submitting (meta)data to ENA" help="If yes is selected then NO submission will be performed."/>
         </section>
     </xml>
     <xml name="run_inputs_macro">
         <conditional name="run_input_format_conditional">
-            <param name="run_input_format" type="select" label="Select runs input format">
-                <option value="multiple_selection_list" selected="True">Select individual datasets or datasets collection</option>
-                <option value="paired_list" selected="False">Input from a paired collection</option>
+            <param name="run_input_format" type="select" label="Select input data">
+                <option value="multiple_selection_list" selected="True">Dataset or dataset collection</option>
+                <option value="paired_list" selected="False">Paired dataset collection</option>
             </param>
             <when value="multiple_selection_list">
-                <param name="add_extension" type="boolean" checked="False" label="Add .fastq.(gz,.bz2) extension to the Galaxy dataset names to match the ones described in the input tables?"/>
-                <param name="data" type="data" format="fastq,fastqsanger,fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" multiple="True" label="Select individual datasets or a dataset collection" help="Names should match the compressed run's files names defined in the metadata"/>
+                <param name="add_extension" type="boolean" checked="False" label="Add .fastq (.gz, .bz2) extension to the Galaxy dataset names to match the ones described in the input tables?"/>
+                <param name="data" type="data" format="fastq,fastqsanger,fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" multiple="True" label="Select dataset or dataset collection" help="Names should match the compressed run's files names defined in the metadata"/>
             </when>
             <when value="paired_list">
-                <param name="paired_end_collection" collection_type="list:paired" type="data_collection" format="fastq,fastqsanger,fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" label="List of paired-end runs files" help="Names should match the compressed run's files names defined in the metadata" />
+                <param name="paired_end_collection" collection_type="list:paired" type="data_collection" format="fastq,fastqsanger,fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" label="List of paired-end sequencing data files" help="Names should match the compressed run's files names defined in the metadata" />
             </when>
         </conditional>
     </xml>
     <xml name="table_inputs_macro">
         <conditional name="input_format_conditional">
-            <param name="input_format" type="select" label="Would you like to submit pregenerated table files or interactively define the input structures?">
-                <option value="excel_tables" selected="True">User generated metadata tables based on Excel template</option>
-                <option value="build_tables" selected="False">Interactive generation of the study structure (only recommended for small studies)</option>
-                <option value="user_generated_tables" selected="False">User generated tabular files (studies - samples - experiments - runs) </option>
+            <param name="input_format" type="select" label="Select the metadata input method">
+                <option value="excel_tables" selected="True">Excel file</option>
+                <option value="user_generated_tables" selected="False">Tabular files (studies - samples - experiments - runs)</option>
+                <option value="isa_json" selected="False">ISA json file</option>
+                <option value="build_tables" selected="False">Interactively (only recommended for small studies)</option>
             </param>
             <when value="excel_tables">
                 <!--<param name="viral_submission" type="boolean" label="Does your submission data belong to a viral sample?" help="If you select yes then your data will be submitted using the ENA virus pathogen reporting standard checklist (see: https://ena-browser-docs.readthedocs.io/en/latest/help_and_guides/sars-cov-2-submissions.html)" />-->
                 <expand macro="checklist_input_macro"/>
-                <param name="xlsx_file" type="data" format="xlsx" label="Select Excel (xlsx) file based on template" />
+                <param name="xlsx_file" type="data" format="xlsx" label="Select Excel (.xlsx) file based on template" />
                 <expand macro="run_inputs_macro" />
             </when>
             <when value="user_generated_tables">
@@ -87,7 +89,7 @@
                 <param name="runs_users_table" type="data" format="tabular" multiple="False" label="Runs table" help="Runs metadata file"/>
             </when>
             <when value="build_tables">
-                <param name="add_extension" type="boolean" checked="False" label="Add .fastq.(gz.bz2) extension to the Galaxy dataset names to match the ones described in the input tables?"/>
+                <param name="add_extension" type="boolean" checked="False" label="Add .fastq (.gz, .bz2) extension to the Galaxy dataset names to match the ones described in the input tables?"/>
                 <conditional name="conditional_viral_metadata">
                     <param name="viral_sample" type="select" label="Select your sample type" help="Non-viral interactive submissions lack specific sample checklist attributes and are suboptimal. It's highly recommended to use Excel or TSV templates as input for a more comprehensive submission.">
                         <option value="True" selected="True">Viral</option>
@@ -101,8 +103,13 @@
                     </when>
                 </conditional>
             </when>
+            <when value="isa_json">
+                <param name="isa_json_file" type="data" format="json" label="Select ISA json file" />
+                <param name="isa_assay_stream" type="text" optional="False" help="List the assay_stream values from the comment field in the assays list of the ISA-json you want to submit." label="Specify the ISA json assay stream(s)" />
+                <expand macro="run_inputs_macro" />
+            </when>
         </conditional>
-        <param name="center" type="text" optional="False" label="Affiliation center"/>
+        
     </xml>
     <xml name="viral_samples">
         <repeat name="rep_study" title="Study" min="1">