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changeset 0:382518f24d6d draft

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"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/ena_upload commit 57b434bcf493554d060a99b65e66f274d5c00e0a"
author iuc
date Sat, 28 Nov 2020 09:45:44 +0000
parents
children 57251c760cab
files README.md ena_upload.xml extract_tables.py process_xlsx.py samples_macros.xml test-data/1.fastqsanger.gz test-data/metadata_test_nonviral.xlsx test-data/metadata_test_viral.xlsx test-data/sample.fq tool-data/geographic_location_1.loc.sample tool-data/host_health_state_1.loc.sample tool-data/host_sex_1.loc.sample tool-data/instrument_model.loc.sample tool-data/library_layout.loc.sample tool-data/library_selection.loc.sample tool-data/library_source.loc.sample tool-data/library_strategy.loc.sample tool-data/study_type.loc.sample tool_data_table_conf.xml.sample tool_data_table_conf.xml.test
diffstat 20 files changed, 1902 insertions(+), 0 deletions(-) [+]
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--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/README.md	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,31 @@
+# ena-upload-wrapper
+Galaxy wrapper for ena-cli-upload
+
+This tool is shipped in a ready to use Galaxy container found [here](https://github.com/ELIXIR-Belgium/ena-upload-container).
+
+## Setting up credentials on Galaxy
+
+The admin of the server can set up global credentials through a file with the format:
+```
+username: webin_id
+password: webin_password
+```
+
+The path to this file must be exported as an environment variable called $GALAXY_ENA_SECRETS
+
+Alternatively, the admin can enable users to set their own credentials for this tool.
+To enable it, make sure the file `config/user_preferences_extra_conf.yml` has the following section:
+
+```
+    ena_webin_account:
+        description: Your ENA Webin account details
+        inputs:
+            - name: webin_id
+              label: ENA Webin ID
+              type: text
+              required: False
+            - name: password
+              label: Password
+              type:  password
+              required: False
+```
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/ena_upload.xml	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,549 @@
+<tool id="ena_upload" name="ENA Upload tool" version="0.3" profile="20.01" license="MIT">
+    <macros>
+        <token name="@VERSION@">0.2.4</token>
+        <import>samples_macros.xml</import>
+    </macros>
+    <requirements>
+        <requirement type="package" version="@VERSION@">ena-upload-cli</requirement>
+        <requirement type="package" version="1.2.0">xlrd</requirement>
+    </requirements>
+    <command detect_errors="exit_code"><![CDATA[
+mkdir ./submission_files; 
+
+#set working_dir = os.getcwd()
+#set $dry_run_option = "False"
+#set viral_submission = "False"
+#if $action_options.input_format_conditional.input_format == "build_tables":
+  python '$__tool_directory__/extract_tables.py' --action $action_options.action --out_dir ./submission_files --studies $studies_json;
+  #set $studies_table_path = './submission_files/studies.tsv'
+  #set $samples_table_path =   './submission_files/samples.tsv'
+  #set $experiments_table_path = './submission_files/experiments.tsv'
+  #set $runs_table_path =  './submission_files/runs.tsv'
+#end if
+
+#if $action_options.input_format_conditional.input_format == "excel_tables":
+    python '$__tool_directory__/process_xlsx.py'
+    #if $action_options.input_format_conditional.viral_submission == "true":
+        --vir 
+    #end if
+    --action '$action_options.action' --form '$action_options.input_format_conditional.xlsx_file' --out_dir ./submission_files ;
+    #set $studies_table_path = './submission_files/studies.tsv'
+    #set $samples_table_path =   './submission_files/samples.tsv'
+    #set $experiments_table_path = './submission_files/experiments.tsv'
+    #set $runs_table_path =  './submission_files/runs.tsv'
+    #if $action_options.input_format_conditional.dry_run == "true":
+      #set $dry_run_option = "True"
+    #end if
+#end if
+
+#if $action_options.input_format_conditional.input_format != "user_generated_tables":
+    cp $studies_table_path $studies_table_out;
+    cp $samples_table_path $samples_table_out;
+    cp $experiments_table_path $experiments_table_out;
+    cp $runs_table_path $runs_table_out;
+    #if $action_options.input_format_conditional.dry_run == "true":
+      #set $dry_run_option = "True"
+    #end if
+#end if
+
+
+#if $dry_run_option == "False" and $action_options.test_submit == "False":
+    webin_id=`grep 'username' $credentials`;
+    if [ "\$webin_id" = "" ]; then
+      ## No credentials in user defined preferences    
+      ## Fallback to global defined credentials (if exist)   
+      #import os
+      #if os.path.isfile(os.environ.get('GALAXY_ENA_SECRETS', '')):
+          credentials_path=\${ENA_SECRETS};     
+          webin_id=`grep 'username' \$GALAXY_ENA_SECRETS`;
+          if [ "\$webin_id" = "" ]; then
+              echo "No global credentials defined. Check your GALAXY_ENA_SECRETS file or set your credentials via: User -> Preferences -> Manage Information";
+              exit 1;
+          fi;
+      #else:
+          echo "No ENA credentials defined. Set your credentials via: User -> Preferences -> Manage Information";
+          exit 1;
+      #end if
+    else
+      credentials_path='$credentials';
+    fi;
+#end if
+
+#if $action_options.test_submit == "True":
+    credentials_path='test_fake_path';
+#end if
+
+## create the list of files to upload and make the symlinks 
+#import re      
+#set $files_to_upload = list()
+#if $action_options.input_format_conditional.input_format == "build_tables":
+    #for $study in $action_options.input_format_conditional.conditional_viral_metadata.rep_study:
+      #for $sample in $study.rep_sample:
+        #for $experiment in $sample.rep_experiment:
+          #for $run in $experiment.rep_runs:
+            #for $file in $run.upload_files:
+                #set $safename_reads_file = re.sub('[^\w\-_\.]', '_', $file.element_identifier)
+                ln -s '$file' $safename_reads_file &&
+                $files_to_upload.append(str($safename_reads_file))
+            #end for
+          #end for
+        #end for
+      #end for
+    #end for
+#else:
+    #for $file in $action_options.input_format_conditional.data:
+        #set $safename_reads_file = re.sub('[^\w\-_\.]', '_', $file.element_identifier)
+        ln -s '$file' $safename_reads_file &&
+        $files_to_upload.append(str($safename_reads_file))
+    #end for
+#end if
+
+
+#if $dry_run_option == "False":
+ena-upload-cli
+    --tool 'ena-upload-cli v@VERSION@ @ Galaxy'
+    --action '$action_options.action'
+    --center '$action_options.center'
+    --secret \${credentials_path}
+    --data
+    #for $dataset in $files_to_upload:
+        '$dataset'
+    #end for
+#if $action_options.input_format_conditional.input_format == "user_generated_tables":
+    --experiment '$action_options.input_format_conditional.experiments_users_table'
+    --study '$action_options.input_format_conditional.studies_users_table'
+    --run '$action_options.input_format_conditional.runs_users_table'
+    --sample '$action_options.input_format_conditional.samples_users_table'
+    #if "$action_options.input_format_conditional.viral_submission" == "true":
+        --vir
+    #end if
+#else:
+    --experiment '$experiments_table_path'
+    --study '$studies_table_path'
+    --run '$runs_table_path'
+    --sample '$samples_table_path'
+    #if $action_options.input_format_conditional.input_format == "build_tables":
+        #if $action_options.input_format_conditional.conditional_viral_metadata.viral_sample == "true":
+          --vir
+        #end if
+    #else:
+        #if $action_options.input_format_conditional.viral_submission == "true":
+          --vir
+        #end if
+    #end if
+#end if
+
+#if $action_options.submit_dev == "true":
+    -d
+#end if
+  > '$output'
+#else:
+    echo ""
+    exit 0;
+#end if
+
+]]></command>
+    <configfiles>
+        <configfile name="credentials"><![CDATA[
+#set $webin_id = $__user__.extra_preferences.get('ena_webin_account|webin_id', "").strip()
+#set $password = $__user__.extra_preferences.get('ena_webin_account|password', "").strip()
+#if $webin_id != "":
+    username: "$webin_id"
+    password: "$password"
+#end if
+        ]]></configfile>
+        <configfile name="studies_json">
+#import json
+#import re
+#if $action_options.input_format_conditional.input_format == "build_tables":
+  #set $files_to_upload = list()
+  #set $studies = list()
+  #for $study in $action_options.input_format_conditional.conditional_viral_metadata.rep_study:
+    #set samples = list()
+    #for $sample in $study.rep_sample:
+      #set experiments = list()
+      #for $experiment in $sample.rep_experiment:
+        #set runs = list()
+        #for $run in $experiment.rep_runs:
+            #set run_files = list()
+            #for $file in $run.upload_files:
+              #set $safename_reads_file = re.sub('[^\w\-_\.]', '_', $file.element_identifier)
+              $run_files.append(str($safename_reads_file))
+            #end for
+            $runs.append($run_files)
+        #end for
+
+$experiments.append({'title':str($experiment.experiment_title),'experiment_design':str($experiment.experiment_design),'library_strategy':str($experiment.library_strategy),'library_source':str($experiment.library_source),'library_selection':str($experiment.library_selection),'library_layout':str($experiment.library_layout),'insert_size':str($experiment.insert_size),'library_construction_protocol':str($experiment.library_construction_protocol),'platform':str($experiment.platform),'instrument_model':str($experiment.instrument_model),'runs':$runs})
+      #end for
+      #if $action_options.input_format_conditional.conditional_viral_metadata.viral_sample == "true":
+
+$samples.append({'title':str($sample.sample_title),'description':str($sample.sample_description),'tax_name':str($sample.scientific_name),'tax_id':str($sample.tax_id),'collection_date':str($sample.collection_date),'geo_location':str($sample.geo_location_country),'host_common_name':str($sample.host_common_name),'host_subject_id':str($sample.host_subject_id),'host_health_state':str($sample.host_health_state),'host_sex':str($sample.host_sex),'host_scientific_name':str($sample.host_scientific_name),'collector_name':str($sample.collector_name),'collecting_institution':str($sample.collecting_institution),'isolate':str($sample.isolate),'experiments':$experiments})
+      #else:
+
+$samples.append({'title':str($sample.sample_title),'description':str($sample.sample_description),'tax_name':str($sample.scientific_name),'tax_id':str($sample.tax_id),'experiments':$experiments})
+      #end if
+    #end for
+    $studies.append({'title':str($study.study_title),'type':str($study.study_type),'abstract':str($study.study_abstract),'pubmed_id':str($study.study_pubmed_id),'samples':$samples})
+  #end for
+  #echo $json.dumps($studies)
+#end if
+        </configfile>
+    </configfiles>
+    <inputs>
+        <conditional name="action_options">
+            <param name="action" type="select" label="Action to execute">
+                <option value="add" selected="True">Add new data</option>
+                <option value="modify">Modify metadata</option>
+            </param>
+            <when value="add">
+                <param name="submit_dev" type="boolean" label="Submit to test ENA server?" help="By selecting yes the reads will be submitted " />
+                <param name="test_submit" type="hidden" value="False" />
+                <expand macro="table_inputs_macro" />
+            </when>
+            <when value="modify">
+                <expand macro="table_inputs_macro" />
+            </when>
+        </conditional>
+    </inputs>
+    <outputs>
+        <data name="output" format="data" label="${tool.name} on ${on_string}: Upload summary"/>
+        <data name="studies_table_out" format="tabular" label="Studies table">
+            <filter> action_options['input_format_conditional']['input_format'] == "build_tables" or action_options['input_format_conditional']['input_format'] == "excel_tables"</filter>
+        </data>
+        <data name="samples_table_out" format="tabular" label="Samples table">
+            <filter> action_options['input_format_conditional']['input_format'] == "build_tables" or action_options['input_format_conditional']['input_format'] == "excel_tables"</filter>
+        </data>
+        <data name="experiments_table_out" format="tabular" label="Experiments table">
+            <filter> action_options['input_format_conditional']['input_format'] == "build_tables" or action_options['input_format_conditional']['input_format'] == "excel_tables"</filter>
+        </data>
+        <data name="runs_table_out" format="tabular" label="Runs table">
+            <filter> action_options['input_format_conditional']['input_format'] == "build_tables" or action_options['input_format_conditional']['input_format'] == "excel_tables"</filter>
+        </data>
+    </outputs>
+    <tests>
+        <!--Test excel input of VIRAL samples -->
+        <test>
+            <conditional name="action_options">
+                <param name="action" value="add"/>
+                <param name="submit_dev" value="False"/>
+                <conditional name="input_format_conditional">
+                    <param name="input_format" value="excel_tables"/>
+                    <param name="viral_submission" value="True"/>
+                    <param name="dry_run" value="True"/>
+                    <param name="xlsx_file" value="metadata_test_viral.xlsx"/>
+                    <param name="data" value="sample.fq"/>
+                </conditional>
+            </conditional>
+            <param name="center" value="Some research center"/>
+            <output name="experiments_table_out">
+                <assert_contents>
+                    <has_n_lines n="5"/>
+                    <has_n_columns n="17"/>
+                    <has_line_matching expression="alias\tstatus\taccession\ttitle\tstudy_alias\tsample_alias\tdesign_description\tlibrary_name\tlibrary_strategy\tlibrary_source\tlibrary_selection\tlibrary_layout\tinsert_size\tlibrary_construction_protocol\tplatform\tinstrument_model\tsubmission_date" />
+                    <has_line_matching expression="e_(.*)_026\tadd\taccession_ena\tNanopore sequencing\tSARS-CoV-2_genomes_01\ts_(.*)"/>
+                </assert_contents>
+            </output>
+            <output name="studies_table_out">
+                <assert_contents>
+                    <has_n_lines n="2"/>
+                    <has_n_columns n="8"/>
+                    <has_line_matching expression="alias\tstatus\taccession\ttitle\tstudy_type\tstudy_abstract\tpubmed_id\tsubmission_date"/>
+                    <has_line_matching expression="SARS-CoV-2_genomes_01\tadd\tENA_accession\tWhole-genome sequencing of SARS-CoV-2 from Covid-19 patients\tWhole Genome Sequencing\tWhole-genome sequences of SARS-CoV-2 from oro-pharyngeal swabs obtained from Covid-19 patients(.*)"/>
+                </assert_contents>
+            </output>
+            <output name="samples_table_out">
+                <assert_contents>
+                    <has_n_lines n="5"/>
+                    <has_n_columns n="18"/>
+                    <has_line_matching expression="alias\tstatus\taccession\ttitle\tscientific_name\ttaxon_id\tsample_description\tcollection_date\tgeographic_location\thost_common_name\thost_subject_id\thost_health_state\thost_sex\thost_scientific_name\tcollector_name\tcollecting_institution\tisolate\tsubmission_date"/>
+                </assert_contents>
+            </output>
+            <output name="runs_table_out">
+                <assert_contents>
+                    <has_n_lines n="5"/>
+                    <has_n_columns n="8"/>
+                    <has_line_matching expression="alias\tstatus\taccession\texperiment_alias\tfile_name\tfile_format\tfile_checksum\tsubmission_date"/>
+                    <has_line_matching expression="r_(.*)_026\tadd\tena_run_accession\te_(.*)_026\tC026_exp5_clean.fastq.gz\tfastq\tfile_checksum\tsubmission_date_ENA"/>
+                </assert_contents>
+            </output>
+        </test>
+        <!--Test excel input of NON-VIRAL samples-->
+        <test>
+            <conditional name="action_options">
+                <param name="action" value="add"/>
+                <param name="submit_dev" value="False"/>
+                <conditional name="input_format_conditional">
+                    <param name="input_format" value="excel_tables"/>
+                    <param name="viral_submission" value="False"/>
+                    <param name="dry_run" value="True"/>
+                    <param name="xlsx_file" value="metadata_test_nonviral.xlsx"/>
+                    <param name="data" value="sample.fq"/>
+                </conditional>
+            </conditional>
+            <param name="center" value="Some research center"/>
+            <output name="experiments_table_out">
+                <assert_contents>
+                    <has_n_lines n="5"/>
+                    <has_n_columns n="17"/>
+                    <has_line_matching expression="alias\tstatus\taccession\ttitle\tstudy_alias\tsample_alias\tdesign_description\tlibrary_name\tlibrary_strategy\tlibrary_source\tlibrary_selection\tlibrary_layout\tinsert_size\tlibrary_construction_protocol\tplatform\tinstrument_model\tsubmission_date" />
+                </assert_contents>
+            </output>
+            <output name="studies_table_out">
+                <assert_contents>
+                    <has_n_lines n="2"/>
+                    <has_n_columns n="8"/>
+                    <has_line_matching expression="alias\tstatus\taccession\ttitle\tstudy_type\tstudy_abstract\tpubmed_id\tsubmission_date"/>
+                </assert_contents>
+            </output>
+            <output name="samples_table_out">
+                <assert_contents>
+                    <has_n_lines n="5"/>
+                    <has_n_columns n="8"/>
+                        <has_line_matching expression="alias\tstatus\taccession\ttitle\tscientific_name\ttaxon_id\tsample_description\tsubmission_date"/>
+                </assert_contents>
+            </output>
+            <output name="runs_table_out">
+                <assert_contents>
+                    <has_n_lines n="5"/>
+                    <has_n_columns n="8"/>
+                    <has_line_matching expression="alias\tstatus\taccession\texperiment_alias\tfile_name\tfile_format\tfile_checksum\tsubmission_date"/>
+                    <has_line_matching expression="r_(.*)_026\tadd\tena_run_accession\te_(.*)_026\tC026_exp5_clean.fastq.gz\tfastq\tfile_checksum\tsubmission_date_ENA"/>
+                </assert_contents>
+            </output>
+        </test>
+        <!--Test build tables from user input fields NON-VIRAL samples-->
+        <test>
+            <conditional name="action_options">
+                <param name="action" value="add"/>
+                <param name="submit_dev" value="False"/>
+                <conditional name="input_format_conditional">
+                    <param name="input_format" value="build_tables"/>
+                    <param name="dry_run" value="True"/>
+                    <conditional name="conditional_viral_metadata">
+                        <param name="viral_sample" value="False"/>
+                        <repeat name="rep_study">
+                            <param name="study_title" value="Test study title"/>
+                            <param name="study_abstract" value="Test study abstract"/>
+                            <param name="study_type" value="Epigenetics"/>
+                            <param name="study_pubmed_id" value="Test study pubmedID"/>
+                            <repeat name="rep_sample">
+                                <param name="sample_title" value="Test Sample title"/>
+                                <param name="sample_description" value="Test Sample description"/>
+                                <param name="scientific_name" value="Test Sample scientific name"/>
+                                <param name="tax_id" value="Test Sample tax_id"/>
+                                <repeat name="rep_experiment">
+                                    <param name="experiment_title" value="Test experiment title"/>
+                                    <param name="experiment_design" value="Test experiment design description"/>
+                                    <param name="library_strategy" value="CTS"/>
+                                    <param name="library_source" value="GENOMIC"/>
+                                    <param name="library_selection" value="PCR"/>
+                                    <param name="library_layout" value="SINGLE"/>
+                                    <param name="insert_size" value="150"/>
+                                    <param name="library_construction_protocol" value="Test library construction"/>
+                                    <param name="platform" value="ILLUMINA"/>
+                                    <param name="instrument_model" value="Illumina HiSeq 4000"/>
+                                    <repeat name="rep_runs">
+                                        <param name="upload_files" value="1.fastqsanger.gz,sample.fq" ftype="fastqsanger"/>
+                                    </repeat>
+                                </repeat>
+                            </repeat>
+                        </repeat>
+                    </conditional>
+                </conditional>
+            </conditional>
+            <param name="center" value="Some research center"/>
+            <output name="experiments_table_out">
+                <assert_contents>
+                    <has_n_lines n="2"/>
+                    <has_n_columns n="17"/>
+                </assert_contents>
+            </output>
+            <output name="studies_table_out">
+                <assert_contents>
+                    <has_n_lines n="2"/>
+                    <has_n_columns n="8"/>
+                    <has_line_matching expression="alias\tstatus\taccession\ttitle\tstudy_type\tstudy_abstract\tpubmed_id\tsubmission_date"/>
+                </assert_contents>
+            </output>
+            <output name="samples_table_out">
+                <assert_contents>
+                    <has_n_lines n="2"/>
+                    <has_n_columns n="8"/>
+                </assert_contents>
+            </output>
+            <output name="runs_table_out">
+                <assert_contents>
+                    <has_n_lines n="3"/>
+                    <has_n_columns n="8"/>
+                    <has_line_matching expression="alias\tstatus\taccession\texperiment_alias\tfile_name\tfile_format\tfile_checksum\tsubmission_date"/>
+                </assert_contents>
+            </output>
+        </test>
+        <!--Test RUN failing build tables from user input fields NON-VIRAL samples-->
+        <test expect_failure="true">
+            <conditional name="action_options">
+                <param name="action" value="add"/>
+                <param name="submit_dev" value="True"/>
+                <conditional name="input_format_conditional">
+                    <param name="input_format" value="build_tables"/>
+                    <param name="dry_run" value="False"/>
+                    <conditional name="conditional_viral_metadata">
+                        <param name="viral_sample" value="False"/>
+                        <repeat name="rep_study">
+                            <param name="study_title" value="Test study title"/>
+                            <param name="study_abstract" value="Test study abstract"/>
+                            <param name="study_type" value="Epigenetics"/>
+                            <param name="study_pubmed_id" value="Test study pubmedID"/>
+                            <repeat name="rep_sample">
+                                <param name="sample_title" value="Test Sample title"/>
+                                <param name="sample_description" value="Test Sample description"/>
+                                <param name="scientific_name" value="Test Sample scientific name"/>
+                                <param name="tax_id" value="Test Sample tax_id"/>
+                                <repeat name="rep_experiment">
+                                    <param name="experiment_title" value="Test experiment title"/>
+                                    <param name="experiment_design" value="Test experiment design description"/>
+                                    <param name="library_strategy" value="CTS"/>
+                                    <param name="library_source" value="GENOMIC"/>
+                                    <param name="library_selection" value="PCR"/>
+                                    <param name="library_layout" value="SINGLE"/>
+                                    <param name="insert_size" value="150"/>
+                                    <param name="library_construction_protocol" value="Test library construction"/>
+                                    <param name="platform" value="ILLUMINA"/>
+                                    <param name="instrument_model" value="Illumina HiSeq 4000"/>
+                                    <repeat name="rep_runs">
+                                        <param name="upload_files" value="1.fastqsanger.gz,sample.fq" ftype="fastqsanger"/>
+                                    </repeat>
+                                </repeat>
+                            </repeat>
+                        </repeat>
+                    </conditional>
+                </conditional>
+            </conditional>
+            <param name="center" value="Some research center"/>
+            <assert_stdout>
+                <has_text_matching expression="No ENA credentials defined"/>
+            </assert_stdout>
+        </test>
+        <!--Test with submit_test to skip credentials checksRUN failing build tables from user input fields NON-VIRAL samples-->
+        <test expect_failure="true">
+            <conditional name="action_options">
+                <param name="action" value="add"/>
+                <param name="submit_dev" value="True"/>
+                <param name="test_submit" value="True"/>
+                <conditional name="input_format_conditional">
+                    <param name="input_format" value="build_tables"/>
+                    <param name="dry_run" value="False"/>
+                    <conditional name="conditional_viral_metadata">
+                        <param name="viral_sample" value="False"/>
+                        <repeat name="rep_study">
+                            <param name="study_title" value="Test study title"/>
+                            <param name="study_abstract" value="Test study abstract"/>
+                            <param name="study_type" value="Epigenetics"/>
+                            <param name="study_pubmed_id" value="Test study pubmedID"/>
+                            <repeat name="rep_sample">
+                                <param name="sample_title" value="Test Sample title"/>
+                                <param name="sample_description" value="Test Sample description"/>
+                                <param name="scientific_name" value="Test Sample scientific name"/>
+                                <param name="tax_id" value="Test Sample tax_id"/>
+                                <repeat name="rep_experiment">
+                                    <param name="experiment_title" value="Test experiment title"/>
+                                    <param name="experiment_design" value="Test experiment design description"/>
+                                    <param name="library_strategy" value="CTS"/>
+                                    <param name="library_source" value="GENOMIC"/>
+                                    <param name="library_selection" value="PCR"/>
+                                    <param name="library_layout" value="SINGLE"/>
+                                    <param name="insert_size" value="150"/>
+                                    <param name="library_construction_protocol" value="Test library construction"/>
+                                    <param name="platform" value="ILLUMINA"/>
+                                    <param name="instrument_model" value="Illumina HiSeq 4000"/>
+                                    <repeat name="rep_runs">
+                                        <param name="upload_files" value="1.fastqsanger.gz,sample.fq" ftype="fastqsanger"/>
+                                    </repeat>
+                                </repeat>
+                            </repeat>
+                        </repeat>
+                    </conditional>
+                </conditional>
+            </conditional>
+            <param name="center" value="Some research center"/>
+            <assert_command>
+                <has_text_matching expression="ena-upload-cli"/>
+                <has_text_matching expression="--data '1.fastqsanger.gz' 'sample.fq'"/>
+                <has_text_matching expression="--action 'add' --center 'Some research center'"/>
+            </assert_command>
+            <assert_stderr>
+                <has_text_matching expression="ENA_upload: error: Oops, the file test_fake_path does not exist"/>
+            </assert_stderr>
+        </test>
+        <!--test viral submission - User input metadata-->
+        <test expect_failure="true">
+            <conditional name="action_options">
+                <param name="action" value="add"/>
+                <param name="submit_dev" value="False"/>
+                <param name="test_submit" value="True"/>
+                <conditional name="input_format_conditional">
+                    <param name="input_format" value="build_tables"/>
+                    <param name="dry_run" value="False"/>
+                    <conditional name="conditional_viral_metadata">
+                        <param name="viral_sample" value="True"/>
+                        <repeat name="rep_study">
+                            <param name="study_title" value="Test study title"/>
+                            <param name="study_abstract" value="Test study abstract"/>
+                            <param name="study_type" value="Epigenetics"/>
+                            <param name="study_pubmed_id" value="Test study pubmedID"/>
+                            <repeat name="rep_sample">
+                                <param name="sample_title" value="Test Sample title"/>
+                                <param name="sample_description" value="Test Sample description"/>
+                                <param name="scientific_name" value="Test Sample scientific name"/>
+                                <param name="tax_id" value="Test Sample tax_id"/>
+                                <param name="collection_date" value="2020"/>
+                                <param name="geo_location_country" value="Belgium"/>
+                                <param name="host_common_name" value="Human"/>
+                                <param name="host_subject_id" value="Patient_001"/>
+                                <param name="host_health_state" value="healthy"/>
+                                <param name="host_sex" value="female"/>
+                                <param name="host_scientific_name" value="homo sapiens"/>
+                                <param name="collector_name" value="John The Collector"/>
+                                <param name="collecting_institution" value="Hospital 01"/>
+                                <param name="isolate" value="sample_001"/>
+                                <repeat name="rep_experiment">
+                                    <param name="experiment_title" value="Test experiment title"/>
+                                    <param name="experiment_design" value="Test experiment design description"/>
+                                    <param name="library_strategy" value="CTS"/>
+                                    <param name="library_source" value="GENOMIC"/>
+                                    <param name="library_selection" value="PCR"/>
+                                    <param name="library_layout" value="SINGLE"/>
+                                    <param name="insert_size" value="150"/>
+                                    <param name="library_construction_protocol" value="Test library construction"/>
+                                    <param name="platform" value="ILLUMINA"/>
+                                    <param name="instrument_model" value="Illumina HiSeq 4000"/>
+                                    <repeat name="rep_runs">
+                                        <param name="upload_files" value="1.fastqsanger.gz,sample.fq" ftype="fastqsanger"/>
+                                    </repeat>
+                                </repeat>
+                            </repeat>
+                        </repeat>
+                    </conditional>
+                </conditional>
+            </conditional>
+            <param name="center" value="Some research center"/>
+            <assert_command>
+                <has_text_matching expression="ena-upload-cli"/>
+                <has_text_matching expression="--data '1.fastqsanger.gz' 'sample.fq'"/>
+                <has_text_matching expression="--action 'add' --center 'Some research center'"/>
+                <has_text_matching expression="--vir"/>
+            </assert_command>
+            <assert_stderr>
+                <has_text_matching expression="ENA_upload: error: Oops, the file test_fake_path does not exist"/>
+            </assert_stderr>
+        </test>
+    </tests>
+    <help><![CDATA[
+        This is a wrapper for the ENA upload tool in https://github.com/usegalaxy-eu/ena-upload-cli
+        The input metadata can be submitted following the tabular format of the templates in https://github.com/usegalaxy-eu/ena-upload-cli/tree/master/example_tables
+        It is also possible to submit an excel file by following the template in https://drive.google.com/file/d/1ncC22--tW2v-EI-te_r86sAZujIPAjlX/view?usp=sharing
+        For viral submissions a larger set of metadata is required, you can find the template in https://drive.google.com/file/d/1U4VdcczsIecIXxseV8svE1zO_CBUadog/view?usp=sharing 
+    ]]></help>
+    <citations>
+    </citations>
+</tool>
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/extract_tables.py	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,93 @@
+import argparse
+import json
+import pathlib
+from datetime import datetime
+
+FILE_FORMAT = 'fastq'
+
+parser = argparse.ArgumentParser()
+parser.add_argument('--studies', dest='studies_json_path', required=True)
+parser.add_argument('--out_dir', dest='out_path', required=True)
+parser.add_argument('--action', dest='action', required=True)
+args = parser.parse_args()
+
+with open(args.studies_json_path, 'r') as studies_json_file:
+    studies_dict = json.load(studies_json_file)
+studies_table = open(pathlib.Path(args.out_path) / 'studies.tsv', 'w')
+studies_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'study_type',
+                               'study_abstract', 'pubmed_id', 'submission_date']) + '\n')
+samples_table = open(pathlib.Path(args.out_path) / 'samples.tsv', 'w')
+experiments_table = open(pathlib.Path(args.out_path) / 'experiments.tsv', 'w')
+experiments_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'study_alias',
+                                   'sample_alias', 'design_description', 'library_name',
+                                   'library_strategy', 'library_source', 'library_selection',
+                                   'library_layout', 'insert_size',
+                                   'library_construction_protocol', 'platform', 'instrument_model',
+                                   'submission_date']) + '\n')
+runs_table = open(pathlib.Path(args.out_path) / 'runs.tsv', 'w')
+runs_table.write('\t'.join(['alias', 'status', 'accession', 'experiment_alias', 'file_name',
+                            'file_format', 'file_checksum', 'submission_date']) + '\n')
+
+action = args.action
+
+dt_oobj = datetime.now(tz=None)
+timestamp = dt_oobj.strftime("%Y%m%d_%H:%M:%S")
+for study_index, study in enumerate(studies_dict):
+    study_alias = 'study_' + str(study_index) + '_' + timestamp
+    studies_table.write('\t'.join([study_alias, action, 'ENA_accession', study['title'],
+                                   study['type'], study['abstract'], study['pubmed_id'],
+                                   'ENA_submission_data']))
+    if "geo_location" in study['samples'][0].keys():           # sample belongs to a viral sample
+        samples_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'scientific_name',
+                                       'taxon_id', 'sample_description', 'collection_date',
+                                       'geographic_location', 'host_common_name', 'host_subject_id',
+                                       'host_health_state', 'host_sex', 'host_scientific_name',
+                                       'collector_name', 'collecting_institution', 'isolate',
+                                       'submission_date']) + '\n')
+    else:
+        samples_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'scientific_name',
+                                       'taxon_id', 'sample_description', 'submission_date']) + '\n')
+    for sample_index, sample in enumerate(study['samples']):
+        sample_alias = 'sample_' + str(sample_index) + '_' + timestamp
+        if "geo_location" in sample.keys():  # sample belongs to a viral sample
+            if sample['collector_name'] == '':
+                sample['collector_name'] = 'unknown'
+            samples_table.write('\t'.join([sample_alias, action, 'ena_accession', sample['title'],
+                                           sample['tax_name'], sample['tax_id'],
+                                           sample['description'], sample['collection_date'],
+                                           sample['geo_location'], sample['host_common_name'],
+                                           sample['host_subject_id'], sample['host_health_state'],
+                                           sample['host_sex'], sample['host_scientific_name'],
+                                           sample['collector_name'],
+                                           sample['collecting_institution'], sample['isolate'],
+                                           'ENA_submission_date']) + '\n')
+        else:
+            samples_table.write('\t'.join([sample_alias, action, 'ena_accession', sample['title'],
+                                           sample['tax_name'], sample['tax_id'],
+                                           sample['description'], 'ENA_submission_date']) + '\n')
+        for exp_index, exp in enumerate(sample['experiments']):
+            exp_alias = 'experiment_' + str(exp_index) + '.' + str(sample_index) + '_' + timestamp
+            lib_alias = 'library_' + str(exp_index) + '_' + str(sample_index)
+            experiments_table.write('\t'.join([exp_alias, action, 'accession_ena', exp['title'],
+                                               study_alias, sample_alias, exp['experiment_design'],
+                                               lib_alias, exp['library_strategy'],
+                                               exp['library_source'], exp['library_selection'],
+                                               exp['library_layout'].lower(), exp['insert_size'],
+                                               exp['library_construction_protocol'],
+                                               exp['platform'], exp['instrument_model'],
+                                               'submission_date_ENA']) + '\n')
+            run_index = 0
+            # exp['runs'] is a list of lists
+            for run in exp['runs']:
+                run_index += 1
+                run_alias = '.'.join(['run_' + str(run_index), str(exp_index), str(sample_index)]) \
+                            + '_' + timestamp
+                for file_entry in run:
+                    runs_table.write('\t'.join([run_alias, action, 'ena_run_accession', exp_alias,
+                                                file_entry, FILE_FORMAT, 'file_checksum',
+                                                'submission_date_ENA']) + '\n')
+
+studies_table.close()
+samples_table.close()
+experiments_table.close()
+runs_table.close()
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/process_xlsx.py	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,173 @@
+import argparse
+import pathlib
+import sys
+
+import xlrd
+
+
+FILE_FORMAT = 'fastq'
+
+
+def extract_data(xl_sheet, expected_columns):
+    """
+    1. Check that the columns I expect are present in the sheet
+    (any order and mixed with others, it's just a verification that
+    the user filled the correct template)
+    2. Fill a dictionary with the rows data indexed by first column in list"""
+    sheet_columns = {}
+    for sh_col in range(xl_sheet.ncols):
+        if xl_sheet.cell(0, sh_col).value in expected_columns:
+            if xl_sheet.cell(0, sh_col).value in sheet_columns.keys():
+                sys.exit("Duplicated columns")
+            else:
+                sheet_columns[xl_sheet.cell(0, sh_col).value] = sh_col
+    for col in range(len(expected_columns)):
+        assert expected_columns[col] in sheet_columns.keys(), \
+            "Expected column %s not found" % expected_columns[col]
+
+    # fetch rows in a dict
+    data_dict = {}
+    # the first of the expected columns will be the index
+    index_col = sheet_columns[expected_columns[0]]
+    # skip first 2 rows: column names + comments rows
+    for row_id in range(2, xl_sheet.nrows):
+        row_dict = {}
+        for col in range(1, len(expected_columns)):
+            sheet_col_index = sheet_columns[expected_columns[col]]
+            row_dict[expected_columns[col]] = xl_sheet.cell(row_id, sheet_col_index).value
+        # should check for duplicate alias/ids?
+        data_dict[xl_sheet.cell(row_id, index_col).value] = row_dict
+    return data_dict
+
+
+parser = argparse.ArgumentParser()
+parser.add_argument('--form', dest='xlsx_path', required=True)
+parser.add_argument('--out_dir', dest='out_path', required=True)
+parser.add_argument('--action', dest='action', required=True)
+parser.add_argument('--vir', dest='viral_submission', required=False, action='store_true')
+args = parser.parse_args()
+
+xl_workbook = xlrd.open_workbook(args.xlsx_path)
+
+# PARSE STUDIES
+#################
+xl_sheet = xl_workbook.sheet_by_name('ENA_study')
+if xl_sheet.nrows < 3:
+    raise ValueError('No entries found in studies sheet')
+studies_dict = {}
+studies_col = ['alias', 'title', 'study_type', 'study_abstract']
+studies_dict = extract_data(xl_sheet, studies_col)
+
+# PARSE SAMPLES
+#################
+xl_sheet = xl_workbook.sheet_by_name('ENA_sample')
+if xl_sheet.nrows < 3:
+    raise ValueError('No entries found in samples')
+if args.viral_submission:
+    samples_cols = ['alias', 'title', 'scientific_name', 'sample_description',
+                    'geographic location (country and/or sea)', 'host common name',
+                    'host health state', 'host sex', 'host scientific name', 'collector name',
+                    'collection date', 'collecting institution', 'isolate']
+else:
+    samples_cols = ['alias', 'title', 'scientific_name', 'sample_description']
+samples_dict = extract_data(xl_sheet, samples_cols)
+
+# PARSE EXPERIMENTS
+#################
+xl_sheet = xl_workbook.sheet_by_name('ENA_experiment')
+if xl_sheet.nrows < 3:
+    raise ValueError('No experiments found in experiments sheet')
+exp_columns = ['alias', 'title', 'study_alias', 'sample_alias', 'design_description', 'library_name',
+               'library_strategy', 'library_source', 'library_selection', 'library_layout',
+               'insert_size', 'library_construction_protocol', 'platform', 'instrument_model']
+experiments_dict = extract_data(xl_sheet, exp_columns)
+
+# PARSE RUNS SHEET
+#################
+xl_sheet = xl_workbook.sheet_by_name('ENA_run')
+if xl_sheet.nrows < 3:
+    raise ValueError('No entries found in runs sheet')
+run_cols = ['alias', 'experiment_alias', 'file_name', 'file_format']
+runs_dict = extract_data(xl_sheet, run_cols)
+
+# WRITE HEADERS TO TABLES
+studies_table = open(pathlib.Path(args.out_path) / 'studies.tsv', 'w')
+studies_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'study_type',
+                               'study_abstract', 'pubmed_id', 'submission_date']) + '\n')
+samples_table = open(pathlib.Path(args.out_path) / 'samples.tsv', 'w')
+if args.viral_submission:
+    samples_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'scientific_name',
+                                   'taxon_id', 'sample_description', 'collection_date',
+                                   'geographic_location', 'host_common_name', 'host_subject_id',
+                                   'host_health_state', 'host_sex', 'host_scientific_name',
+                                   'collector_name', 'collecting_institution', 'isolate',
+                                   'submission_date']) + '\n')
+else:
+    samples_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'scientific_name',
+                                   'taxon_id', 'sample_description', 'submission_date']) + '\n')
+
+experiments_table = open(pathlib.Path(args.out_path) / 'experiments.tsv', 'w')
+experiments_table.write('\t'.join(['alias', 'status', 'accession', 'title', 'study_alias',
+                                   'sample_alias', 'design_description', 'library_name',
+                                   'library_strategy', 'library_source', 'library_selection',
+                                   'library_layout', 'insert_size', 'library_construction_protocol',
+                                   'platform', 'instrument_model', 'submission_date']) + '\n')
+
+runs_table = open(pathlib.Path(args.out_path) / 'runs.tsv', 'w')
+runs_table.write('\t'.join(['alias', 'status', 'accession', 'experiment_alias', 'file_name',
+                            'file_format', 'file_checksum', 'submission_date']) + '\n')
+action = args.action
+
+# WRITE  DICTIONARIES TO TABLE FILES
+
+# ADD A TIMESTAMP TO THE ALIAS? SEEMS LIKE ENA REQUIRES ALL ENTRIES FOR A WEBIN TO HAVE UNIQUE IDS?
+# dt_oobj = datetime.now(tz=None)
+# timestamp = dt_oobj.strftime("%Y%m%d_%H:%M:%S")
+for study_alias, study in studies_dict.items():
+    # study_alias = study_alias + '_' + timestamp
+    studies_table.write('\t'.join([study_alias, action, 'ENA_accession', study['title'],
+                                   study['study_type'], study['study_abstract'], '',
+                                   'ENA_submission_data']) + '\n')  # assuming no pubmed_id
+for sample_alias, sample in samples_dict.items():
+    # sample_alias = sample_alias + '_' + timestamp
+    if args.viral_submission:
+        if sample['collector name'] == '':
+            sample['collector name'] = 'unknown'
+        samples_table.write('\t'.join([sample_alias, action, 'ena_accession', sample['title'],
+                                       sample['scientific_name'], 'tax_id_updated_by_ENA',
+                                       sample['sample_description'], sample['collection date'],
+                                       sample['geographic location (country and/or sea)'],
+                                       sample['host common name'], 'host subject id',
+                                       sample['host health state'], sample['host sex'],
+                                       sample['host scientific name'], sample['collector name'],
+                                       sample['collecting institution'], sample['isolate'],
+                                       'ENA_submission_date']) + '\n')
+    else:
+        samples_table.write('\t'.join([sample_alias, action, 'ena_accession', sample['title'],
+                                       sample['scientific_name'], 'tax_id_updated_by_ENA',
+                                       sample['sample_description']]) + '\n')
+    for exp_alias, exp in experiments_dict.items():
+        # should I check here if any experiment has a study or sample alias that is incorrect?
+        # (not listed in the samples or study dict)
+        # process the experiments for this sample
+        if exp['sample_alias'] == sample_alias:
+            lib_alias = 'library_' + exp_alias + '_' + exp['sample_alias']
+            experiments_table.write('\t'.join([exp_alias, action, 'accession_ena', exp['title'],
+                                               exp['study_alias'], sample_alias,
+                                               exp['design_description'], lib_alias,
+                                               exp['library_strategy'], exp['library_source'],
+                                               exp['library_selection'],
+                                               exp['library_layout'].lower(),
+                                               str(int(exp['insert_size'])),
+                                               exp['library_construction_protocol'],
+                                               exp['platform'], exp['instrument_model'],
+                                               'submission_date_ENA']) + '\n')
+            for run_alias, run in runs_dict.items():
+                if run['experiment_alias'] == exp_alias:
+                    runs_table.write('\t'.join([run_alias, action, 'ena_run_accession', exp_alias,
+                                                run['file_name'], FILE_FORMAT, 'file_checksum',
+                                                'submission_date_ENA']) + '\n')
+studies_table.close()
+samples_table.close()
+experiments_table.close()
+runs_table.close()
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/samples_macros.xml	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,191 @@
+<macros>
+
+    <xml name="table_inputs_macro">
+        <conditional name="input_format_conditional">
+            <param name="input_format" type="select" label="Would you like to submit pregenerated table files or interactively define the input structures?">
+                <option value="excel_tables" selected="True">User generated metadata tables based on Excel templates</option>
+                <option value="build_tables" selected="False">Interactive generation of the study structure (recommended for small studies)</option>
+                <option value="user_generated_tables" selected="False">User generated tabular files (studies - samples - experiments - runs) </option>
+            </param>
+            <when value="excel_tables">
+                <param name="viral_submission" type="boolean" label="Does your submission data belong to a viral sample?" help="If you select yes then your data will be submitted using the ENA virus pathogen reporting standard checklist (see: https://ena-browser-docs.readthedocs.io/en/latest/help_and_guides/sars-cov-2-submissions.html)" />
+                <param name="dry_run" type="boolean" label="Print the tables but do not submit the datasets" help="If yes is selected then NO submission will be performed."/>
+                <param name="xlsx_file" type="data" format="xlsx" />
+                <param name="data" type="data" format="fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" multiple="true" label="Select all datasets to upload" help="Compressed reads files listed in the runs table"/>
+            </when>
+            <when value="user_generated_tables">
+                <param name="viral_submission" type="boolean" label="Does your submission data belong to a viral sample?" help="If you select yes then your data will be submitted using the ENA virus pathogen reporting standard checklist (see: https://ena-browser-docs.readthedocs.io/en/latest/help_and_guides/sars-cov-2-submissions.html)" />
+                <param name="data" type="data" format="fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" multiple="true" label="Select all datasets to upload" help="Compressed reads files listed in the runs table"/>
+                <param name="studies_users_table" type="data" format="tabular" multiple="false" label="Studies table" help="Studies metadata file"/>
+                <param name="samples_users_table" type="data" format="tabular" multiple="false" label="Samples table" help="Samples metadata file"/>
+                <param name="experiments_users_table" type="data" format="tabular" multiple="false" label="Experiments table" help="Experiments metadata file"/>
+                <param name="runs_users_table" type="data" format="tabular" multiple="false" label="Runs table" help="Runs metadata file"/>
+            </when>
+            <when value="build_tables">
+                <param name="dry_run" type="boolean" label="Print the tables but do not submit the datasets" help="If yes is selected then NO submission will be performed."/>
+                <conditional name="conditional_viral_metadata">
+                    <param name="viral_sample" type="boolean" label="Does your submission contains viral samples?" />
+                    <when value="true">
+                        <expand macro="viral_samples" />
+                    </when>
+                    <when value="false">
+                        <expand macro="nonviral_samples" />
+                    </when>
+                </conditional>
+            </when>
+        </conditional>
+        <param name="center" type="text" optional="False" label="Affiliation center"/>
+    </xml>
+    <xml name="viral_samples">
+        <repeat name="rep_study" title="Study" min="1">
+            <param name="study_title" type="text" optional="False" label="Please provide a short descriptive title for the study"/>
+            <param name="study_abstract" type="text" optional="True" label="Please provide an abstract to describe the study in detail"/>
+            <param name="study_type" type="select" label="Please select the type of study">
+                    <options from_data_table="study_type">
+                        <column name="value" index="0"/>
+                    </options>
+            </param>
+            <param name="study_pubmed_id" type="text" optional="True" value="" label="Please provide the PubMed id if exists (or leave it blank)"/>
+            <repeat name="rep_sample" title="Samples associated with this study" min="1" >
+                <param name="sample_title" type="text" label="Sample title"/>
+                <param name="sample_description" type="text" help="e.g: liver cells" label="Describe the type of sample"/>
+                <param name="scientific_name" type="text" label="Enter the species of the sample" help="e.g Severe acute respiratory syndrome coronavirus 2"/>
+                <param name="tax_id" type="text" label="Enter the taxonomic ID corresponding to the sample species" />
+                <param name="collection_date" type="text" label="Collection date" optional="True" help="options are: YYYY, YYYY/MM, YYYY/MM/DD, not collected, restricted access or leave blank">
+                    <validator type="regex"  message="Data format is not valid">(^[0-9]{4}(-[0-9]{2}(-[0-9]{2}(T[0-9]{2}:[0-9]{2}(:[0-9]{2})?Z?([+-][0-9]{1,2})?)?)?)?(/[0-9]{4}(-[0-9]{2}(-[0-9]{2}(T[0-9]{2}:[0-9]{2}(:[0-9]{2})?Z?([+-][0-9]{1,2})?)?)?)?)?$)|(^not colected$)|(^not provided$)|(^restricted access$)</validator>
+                </param>
+                <param name="geo_location_country" type="select" label="Select the country where the sample was obtained">
+                    <options from_data_table="geographic_location_1">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <param name="host_common_name" type="text" label="Host common name" help="e.g human"/>
+                <param name="host_subject_id" type="text" label="Host subject id"/>
+                <param name="host_health_state" type="select" label="Host health state">
+                    <options from_data_table="host_health_state_1">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <param name="host_sex" type="select" label="Host sex">
+                    <options from_data_table="host_sex_1">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <param name="host_scientific_name" type="text" label="Host scientific name" help="e.g Homo sapiens"/>
+                <param name="collector_name" type="text" label="Collector name" help="Leave blank if unknown"/>
+                <param name="collecting_institution" type="text" label="Collecting institution"/>
+                <param name="isolate" type="text" label="Isolate"/>
+                <repeat name="rep_experiment" title="Sequencing experiments performed with this sample" min="1" >
+                    <param name="experiment_title" type="text" label="Specify an experiment title" />
+                    <param name="experiment_design" type="text" label="Describe the experiment design" />
+                    <param name="library_strategy" type="select" label="Library strategy" help="The library strategy specifies the sequencing technique intended for this library">
+                        <options from_data_table="library_strategy">
+                            <column name="value" index="0"/>
+                        </options>
+                    </param>
+                    <param name="library_source" type="select" label="Select library source" help="The library source specifies the type of source material that is being sequenced">
+                        <options from_data_table="library_source">
+                            <column name="value" index="0"/>
+                        </options>
+                    </param>
+                    <param name="library_selection" type="select" label="Library selection" help="The library selection specifies whether any method was used to select for or against, enrich, or screen the material being sequenced">
+                        <options from_data_table="library_selection">
+                            <column name="value" index="0"/>
+                        </options>
+                    </param>
+                    <param name="library_layout" type="select" label="Library layout">
+                        <options from_data_table="library_layout">
+                            <column name="value" index="0"/>
+                        </options>
+                    </param>
+                    <param name="insert_size" type="integer" value="0" label="Specify the insert size"/>
+                    <param name="library_construction_protocol" type="text" label="Please describe the library construction protocol"/>
+                    <param name="platform" type="select" label="Select the sequencing platform used">
+                        <option value="LS454">LS454</option>
+                        <option value="ILLUMINA">Illumina</option>
+                        <option value="HELICOS">Helicos</option>
+                        <option value="ABI_SOLID">ABI Solid</option>
+                        <option value="COMPLETE_GENOMICS">Complete Genomics</option>
+                        <option value="BGISEQ">BGI Seq</option>
+                        <option value="OXFORD_NANOPORE">Oxford Nanopore</option>
+                        <option value="PACBIO_SMRT">PacBio</option>
+                        <option value="ION_TORRENT">Ion Torrent</option>
+                        <option value="CAPILLARY">Capillary sequencing</option>
+                    </param>
+                    <param name="instrument_model" type="select" label="Instrument model">
+                        <options from_data_table="instrument_model">
+                            <column name="value" index="0"/>
+                        </options>
+                    </param>
+                    <repeat name="rep_runs" title="Runs executed within this experiment" min="1" >
+                        <param name="upload_files" type="data" format="fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" multiple="true" label="File(s) associated with this run"/>
+                    </repeat>
+                </repeat>
+            </repeat>
+        </repeat>
+    </xml>
+    <xml name="nonviral_samples">
+    <repeat name="rep_study" title="Study" min="1">
+        <param name="study_title" type="text" optional="False" label="Please provide a short descriptive title for the study"/>
+        <param name="study_abstract" type="text" optional="True" label="Please provide an abstract to describe the study in detail"/>
+        <param name="study_type" type="select" label="Please select the type of study">
+                <options from_data_table="study_type">
+                    <column name="value" index="0"/>
+                </options>
+        </param>
+        <param name="study_pubmed_id" type="text" optional="True" value="" label="Please provide the PubMed id if exists (or leave it blank)"/>
+        <repeat name="rep_sample" title="Samples associated with this study" min="1" >
+            <param name="sample_title" type="text" label="Sample title"/>
+            <param name="sample_description" type="text" help="e.g: liver cells" label="Describe the type of sample"/>
+            <param name="scientific_name" type="text" label="Enter the species of the sample" help="e.g Severe acute respiratory syndrome coronavirus 2"/>
+            <param name="tax_id" type="text" label="Enter the taxonomic ID corresponding to the sample species" />
+            <repeat name="rep_experiment" title="Sequencing experiments performed with this sample" min="1" >
+                <param name="experiment_title" type="text" label="Specify an experiment title" />
+                <param name="experiment_design" type="text" label="Describe the experiment design" />
+                <param name="library_strategy" type="select" label="Library strategy" help="The library strategy specifies the sequencing technique intended for this library">
+                    <options from_data_table="library_strategy">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <param name="library_source" type="select" label="Select library source" help="The library source specifies the type of source material that is being sequenced">
+                    <options from_data_table="library_source">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <param name="library_selection" type="select" label="Library selection" help="The library selection specifies whether any method was used to select for or against, enrich, or screen the material being sequenced">
+                    <options from_data_table="library_selection">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <param name="library_layout" type="select" label="Library layout">
+                    <options from_data_table="library_layout">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <param name="insert_size" type="integer" value="0" label="Specify the insert size"/>
+                <param name="library_construction_protocol" type="text" label="Please describe the library construction protocol"/>
+                <param name="platform" type="select" label="Select the sequencing platform used">
+                    <option value="LS454">LS454</option>
+                    <option value="ILLUMINA">Illumina</option>
+                    <option value="HELICOS">Helicos</option>
+                    <option value="ABI_SOLID">ABI Solid</option>
+                    <option value="COMPLETE_GENOMICS">Complete Genomics</option>
+                    <option value="BGISEQ">BGI Seq</option>
+                    <option value="OXFORD_NANOPORE">Oxford Nanopore</option>
+                    <option value="PACBIO_SMRT">PacBio</option>
+                    <option value="ION_TORRENT">Ion Torrent</option>
+                    <option value="CAPILLARY">Capillary sequencing</option>
+                </param>
+                <param name="instrument_model" type="select" label="Instrument model">
+                    <options from_data_table="instrument_model">
+                        <column name="value" index="0"/>
+                    </options>
+                </param>
+                <repeat name="rep_runs" title="Runs executed within this experiment" min="1" >
+                    <param name="upload_files" type="data" format="fastqsanger.gz,fastqsanger.bz2,fastq.gz,fastq.bz2" multiple="true" label="File(s) associated with this run"/>
+                </repeat>
+            </repeat>
+        </repeat>
+    </repeat>
+    </xml>
+</macros>
Binary file test-data/1.fastqsanger.gz has changed
Binary file test-data/metadata_test_nonviral.xlsx has changed
Binary file test-data/metadata_test_viral.xlsx has changed
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/sample.fq	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,400 @@
+@M01368:8:000000000-A3GHV:1:1101:6911:8255/1
+ATCTGGTTCCTACTTCAGGGCCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATT
++
+BCCCCFFFFFFFGGGGGGGGGGGHHHHGHGHHHHHHHHHGGGGGGHHHHGHHHHHHHHHHGHHHHHHGGHGGHHHGHHHHFHHGHHHHHHHHHGHEHEFFGHHEGGCEFGGFHHHBGHHGHHHHGHFHHHGHGHGHGGCDFDDACGGGGGGGAAFFFFFFFFFBAFFFFFB;FFFFFFADDFFFFFFFFFFEFFFFFFFFFFBFFFFFFFFFFFFFFEFFFFFFFFBFEFFFFEFE;DFFFDFBFF/9BFB
+@M01368:8:000000000-A3GHV:1:1101:14518:9998/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGAT
++
+AAAAAFFFFFFFGGGGGGGGGGHGGHHHHGHHHHHHHGCGHHHHHHHHHHHHHHHGGGGGHHHHHHHHHGHHGFHFE5BGEEHFGGGHHHHHHHHFBHHGGGGFHGHHFGHHHHGHHHHHHGEGGGGFHFHGEGHHGGCDGDGHGGGDGGHGGCGGGHGHHH/ACDG?.1FGCDCCGCA.CC@CDCHFHGFFGGGEBFGAB//CEFBFGG.:;D;;A0AFFFFFB..:@ABFF//;BFFFFFBF/9D:A//
+@M01368:8:000000000-A3GHV:1:1101:18422:19051/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+CCCCCFDDDDDFGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGHHHHHHHHHGHHHHHHHHHHHHGGHGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHGCGGGHHHHHHHHHHHHHHHHHHHHHHGFDHGFHCFGGGGFGGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF;FFFFFFFFFFFFFFFFFFFFFFFFFFFFEFBFFFFFFFFFF:FFF.
+@M01368:8:000000000-A3GHV:1:1101:25545:21098/1
+ATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATAAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGGCTTATTTAAGGGGAACGGGTGGGG
++
+33AA?DFD5BDFGGGFEBDGEGHEGHGEGHCEGGHHCHGHHFFHHGFGAGE53FF2FAFFGDE5FFFE5GFBFGAEE1GHHHGHHHEHE3FGHF@GEGEGGHHGG3FAGFFDE?EEE3GFEGFGFGGCG?GHHHFHGGGC@DHFFHD/A<C@EGFDCGGGHFHHHEGFGHBFHG0:CEHFCHGGED.;0CEF.F99B0CFFEEFGGG0FBFBBF0F/FFBDE?/9//9B.FFBFFFFFFBF..A..;@B--
+@M01368:8:000000000-A3GHV:1:1101:5446:12248/1
+AATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTAT
++
+CCCCDFFFFCCFGGGGGGGGFGHHHHHGGGGHHHHHHHHHHHHHHHHGBGHGGHGGHHHHHHHHHHGHGHGGGGGHHHHHHHHGHHHHHHHHHGGGGGHHHHFFGHHHGGGGGGHHHGFGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGGHHHHHHHHHHHHHFHGGGHHHHGGGGGG:FE;EGEGGGGG/;?FGGGGGGGFFFFGGFFFFFFFFFBFFFFFFFFFFBFFFFFFEFFFFFEFFF
+@M01368:8:000000000-A3GHV:1:1101:5861:6452/1
+ATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTT
++
+ABCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHGHHHHGHHHHHHHHHHHGGGGHHHHHHHHFHHHHHHGGHGHGGHGGHHHHHHHGGHFHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHHEGGHHGGGGGGHHHGGGGHGGGGGHHHHHHGGGDCGHHHHGGGGGGGHEFGGGGHGHHHGHGGGFGGGGGGGEGGGGGGG?E0CEFGGGGGFEE9EEFFFFFBFFFFFFFBFFBD.AFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1102:10403:6021/1
+CGCTCCGGGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTG
++
+>A@AAAAD2ADDFFGGGGGFGGHA?EAEFBEAGHFABFGG5FDF5DB1EEGAFDFB53FF5FH@G5FFEHGHEFHFFHBE333GF43GCGGGGE@0?BFGGB0B?FHGFDGGHHHBFFDEGGHGFFFDFE@<1>@FFFGHHHHFHEFGDABFFGG/@DCE<CG1<GF0/DD000=<DHGBDFDCECE/:AC?-;-;9B/ABBB-AD9BFB99AB?BDFBAD-.9..@;=;;..9..9/9;BEF;A:9/BFF
+@M01368:8:000000000-A3GHV:1:1102:10677:23253/1
+CCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTGTCTCTTATACACA
++
+ABBBBFFFFFFFGGGGGGGCGGGHHHHHGHHHHHHHHHGHHHHHHHHHHHGHHHHHGGGGGHGHHHHHHHHHHHHHBGFHHHHGHGHGGHGGGCGGGHHHGGGGGGGHHHGHGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFFFFFFFFFEDBDFFFFFFFEFFFE0F0FBFFFF0FFFFFFFFFFFFFFFFF:
+@M01368:8:000000000-A3GHV:1:1102:13809:1733/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGAGGGCTATTTAGGTTTTATGCTGTCTCTTATACACATCTCCG
++
+BCCBCFFFFFBFGGGGGGGGGGHHHHHHHHHHHGHHGGGGGH3EHHHGHGHHHHHHHHHGGCEGGGHHHGGGFHGGGGGGHHGEAEFHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGCFFGHHFGHHHGHHHHHHCHGFHHHHGGHGGG00EHGHHHGFHHGEHGHFFFHHGGFHHHGGGGGGGGGB;;CFFGGFGFFBFFDFED;E.:A?DFFFFFFFF:FFFFF0BFFBBBFFFFFBFF0BFBF9F.
+@M01368:8:000000000-A3GHV:1:1102:17584:10050/1
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCT
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHHGGHHHGGGGGGHHHGFGDHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGEGGHHHHHHHGHGHHGHHHHGHHHHGGGGFDGHFHGEHHHHHHGFFHHHHHHHHHHHHHHHHHGGHHHHHHHHHHFHHHHHHGGGGGHHHHGGGHHGHHHGGGGGGGGGGGFGFFGGGGGGGCFGGGFGGGGGGGFFFFFFFFFFFFFFFFFFF;.BF9ADF/9;A;DFFF0
+@M01368:8:000000000-A3GHV:1:1102:18842:24844/1
+CACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCT
++
+BBBCBFF@CCBBGGGGGGGGGGHHGHGGHHHGGGGGHHHHHHHHHHHHHHHHHHHHHHHHHHHGHHHHHHFHHHHGGGGGHHHHHHHHHHHHHHHHHHHHGGGHGGHHHHHHGHBFGHHHHHHHHBGHHHHHHGHGGGHFGCGGFHHFHFFHHBHHHHFFHFHHHHGGDHGGBC?;@DFBFFFFFFFFFBFFFFFFFFFFFFFF.B?FB.@;;DFFFFFFFFFFFEE-A./BBBFBFBFFF//BFB/BFF/
+@M01368:8:000000000-A3GHV:1:1102:21788:11027/1
+GCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGTGTTAATTCTG
++
+ABCCBCCBBFFFGGGGGGGGGGGHGHHHHHHGGHGGHHHHHHHHGHHHHHHHHHHHHHHHHHHGHHHHHFGGGGHHHHHHHHHHHHHHHHHHHHHHGHGHGGFCGGCGGGHHHGGGGGGGGGGGGGGGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEF9EFFFFFFFFFFFBFF0FFBBBBFBFBFFFF0
+@M01368:8:000000000-A3GHV:1:1102:5728:8777/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+BBBBBFFFFFAFGG5GGGGGGGHHHGHHHHHHHHHHGGGGGHHHHHHGHHHHHHFGHHHGGGGGFHGHGGGHHHGGGCEGHHGG?F1BGGGGGHHHHHGGGGEGGHHHHGGGGGCGHGGGGCGHHHHHHHHHHHHHHHHGGHHHHGGCEEDFDEGGHHHHHHHCEHHFHHHHGHGFHHHFFGGGFFFGGFGBGFFFFFFFFGFDGGD9EFA.DAFA/;FEFF9FB?/BBF/FFFFBBFFFFF/FFEFFFBB
+@M01368:8:000000000-A3GHV:1:1102:5983:21093/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+AAABCFCABBCFGGGGGGGGGGHHHHHHGFHHHHHHHHGGHHHGHGHHHGGGGFHHHHHHHHGHHHHHHHHHHHHHGGHGGHHHHHHFHGGHHHHFHGHHEHHHHHHHGHHHHHD@FGGHHHHHFFFHHGGHGH?DHHHHHGHGHEGG/@?ADGFGGFFFFAFFFFFFFFFFFFFFFFFFFFFFFAAFFFFFFDFFFFFFFF;D9BFFFFFFFFFFFFFFFFFEFFFBBFFF0BFFFBBFF0EFFFFFFFA
+@M01368:8:000000000-A3GHV:1:1102:7765:18353/1
+CTCCGGGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTC
++
+CCDCCCCCCBCFGGGGGGGGGGGGGGGHHHHHHDHHHHHHHHHHHGGGGGHHGHGHHHGHHHHHHFHHHHGHHHHHHGHGHHHGHHHHHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHGFFHHHHHGHHHHHHHHHHHGHHHHHGCFGGHGHFHHGHGHGHHHHGGFHHHHGGGHGBFGCC=BFFFFFFFF-@DFFFFFFFFFFFFFFFFFFFFFFAFFAEF.::FBFBFFE-A9:BFFFF0
+@M01368:8:000000000-A3GHV:1:1103:10405:17879/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+CBCCCFCCCCCFGGGGGGGGGGHHHHHHHHHHHHGHHHGHHHHHHHHHHHGGGGGGHHHHHHHHHHHHHHHHHHHHGGHGGHHHGHHGHHGHHHHHHHHHCGGFHHHHGHHHHHGCFGGHHGHHHHHHGFHHHGHHHHHHHGHGHGFF/CC?ADAFGFFFFFFFFFFFFFFDFFFFFFFFAFFFFFFFFFFFEDFFFFFFFFFFAFFFFFFFFFFFFFFFFFFFFFFBBFBFBFFFFFFFFFFFFFFFFF?
+@M01368:8:000000000-A3GHV:1:1103:13493:8205/1
+GTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATT
++
+CCCCCFFFFFFFGGGGGGGGGGGGGGGHFHHHHHHHHHHHHHHHHGHHHHHHHHGHHHIHHHHHHHGGGGFHHHHHHHHHHHHHHHHHHHGHGGHGGHHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHH/FGGGGHHHHHHHGGEHHHHHGHHHHHHGHGHEFEFGGFFFFFFFFFFFFFFFFFFFFFAFDFFFFFAFFFF;;@FFEFFFFFFFFFFE=?AFFFFFFFFFFFFFFFFFFBFBBBFFFFEFF
+@M01368:8:000000000-A3GHV:1:1103:14060:21273/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTACTGTCTCTTATACAC
++
+AAABAFCCCCCFGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGFHHHHHHHHHHHHHHHGHHHHGGHGGHHHHHHHHHHHHHHHHHH?GGHHHHHHGHHHHHFEGGGHHHHHHHHHHHHHHHGFHHHFHGHGHGFGCGG@@BCFGFFFFFFF?FFFFFFFFAFFFAD?@FFEEFFFFFFFFFFFFFFFFFFD9BFF/B/FFF/:/9FB9/BFA//;BFB:FFFBB/BFFFFFBFFFFB/
+@M01368:8:000000000-A3GHV:1:1103:14528:12993/1
+GCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGAT
++
+BBBBBFFFBDFFGFBCG2EGFFGHHCF5AFHHHFHFHHHGG?CEHBHHDGFHHGHHGHBGHABFFBGHGDGGGFHGHHGGHHHGGG@E1GEHHHGHHFHH3FEDHHHHGFGHGFHHGHFBGA?FGHHHHHGHHFFGHFDFGGHHH2??<ECFHHGHHHHHHHHHGHH<1DFGHGC<.FCB/<=@DCFFFFFEDA=-AAB9B/9B9B-@?.-;A-AFF.=-=BFEFEDEFFFBFEA-A.B//9F9F//;BBB
+@M01368:8:000000000-A3GHV:1:1103:17657:20856/1
+AAAGCGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTAT
++
+ABB?AABBBBFFGGGGGGGGGGHHHHHHHHGHHHHHHHHHHHHHHHHHGHHHHHHGHHHHGGGGGHHHHHHHGHHFHHHHHHHHHHGGGGGHHHHHHHH3BGGHHHHHHHEHHHHHHHGHHHHGEEGGGHHHHHHHHGHHFHGHGHGHGHHCHGGECCDFGB@AFFFFFFFFFFFFFFFFFDAFFFFFFFFFFFFFCAF;AFFFFEFFBBEFFF9FBBFFFFFFFFFFEFFFFFFFFFFFFF/FFFFBFF9
+@M01368:8:000000000-A3GHV:1:1103:23099:3794/1
+AAGACAGATACTGCGACATAGGGTGTTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCTCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGGATGCCGTCT
++
+BBBBBFFFFFFFGGEEGGFGGGGCFGEHCGGGGGGFHFFEDEHFGGDEHHHHHHGGFECGHHHHGFEFGCGHGGFGGGHBGFH3/BF3GGGHHEEEHHG22???BCFFFFFFHHFHFF@FGHH11GHHHHFGFHHHHGGHHHHEFFGFGHFG1DGFGGGGEDCCCAEGGFFHHFHHHHHHCFBBFGBFFF/0;B0B00;B0BBFGBB9BFGEFGGGFFDEEAB;BDDBFBFFFFF@;.9BF..;-./-A=F
+@M01368:8:000000000-A3GHV:1:1103:25465:20010/1
+GACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATCGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGAAAAAAAAAAAACAACAGAC
++
+ABBBBFFFFBAAGGGFEFGGGGHHFEFFHFGGGGGHHHGHFGGGGGHHHGGGGGGGGHGEEEGGHHHGFHEHFHDGHGHEHGF?FGG?GGGGHHGHF4F?2?DDCDHGHHHHHFG2@FGHHHGH?CFGGHFHFHHHHGDDGGHGGGGGHGFH.<AFAGHHHFHGHHFCGFHHHHHGHHHHBGHHGGDGAGF.CEGCFDGGGGGEFFF=B.FFFEFFFFFFADF?/9//BFF.B/;:>---;--..;.../9
+@M01368:8:000000000-A3GHV:1:1103:25519:6301/1
+AAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGCATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATTTCGT
++
+3A3AAFFFFBFFGGG2CF?4FGHGHHCHGGHHBHGFFAGGHHFFHHCGHFEGCECEGHFFFHGHHGFGHFGDAFDGFFEEFEGGBECC/<A@DFBBEGC--:;GHHHGBECG@:9-9.-9C/ABB?B@?.EDAFFFFBAFBFBFBFFFFF//;BBFFFF/;/9BBF/BBFBFFFFFFFFFEFF??BF/.AF./;B/9FFFFFFBFBFFFBFFFBFFFFF/BF/A---9.9A-B?DFFF/B/B?---.//;.
+@M01368:8:000000000-A3GHV:1:1103:6074:6549/1
+TAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+CCCBCFFFFFCCGGGGGGGGGG5GFHHHHHGHHHGGGGGHHHGHHHHHHHHHHHHGHHHHHHHHHGGHHHHGHHHHHHGGGGHHHHHHHHHHHHHHGHHHHHHHGGHGGHHHHHHHFGHHGHGHHHHHHHHHHHHHGHHHHHGGGGCHHHHEHGHHHEGHHHFGGHHHHGHGHGHF@CCBDFAFFFFFF-CDFFFFFFFFFFFFFAFFFFFEFF;BFF?FEDFFFFFFFF-A./FFFFFFFFFFFF/BFF/
+@M01368:8:000000000-A3GHV:1:1104:11572:8264/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+BABCBFBACCCFGGGGGGGGGGGHHGHHGHHHHGFGCHGHHGFFHEHHHHGGGGFGHHHHHHHHHHHHGHHHHHHHGGGGGHHHFFHHGHHHHHHHHHHHEHHHHHHHGHHGHGGEGEGHHHFHHHHGHHHHHHGGHHHHHGHGEGEHCGG-BGDFGFFFFAFFDFFFFEFFCFFDDFFFFFFFEC>;>=EF?AEFFFF;9;=DAFFFFBBFFFBFFF//;BFB.:FBFFBB/BFFFF/BFFE?EFAFEF9
+@M01368:8:000000000-A3GHV:1:1104:11928:24197/1
+ACGTAGGTGCGATAAATAATGGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATA
++
+CDDCCFCFFFBCGGGGGGGGGGHHHGHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHGHHHHGHHGHHHHGGHGEEGGGGFHHFHHHGHGEHHHHHHHHHHHHHHHHHGGGGGGFGGGGGGGGFFGGGFGFGAEFEFGFEAFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF@D9
+@M01368:8:000000000-A3GHV:1:1104:12288:20635/1
+CACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGCCGCAGCATCTGTCTTTGATTCCTGCCT
++
+ABA?AFBAB2>AFGGGGFFGD5GGHGFFHGHEGGGGHHHHFFHH5FHGHHHFFHEFHHHHHHGGHHHHHGFHGGHGGGGFHGGGFBHHHFGEGHHHHGHGGGGECEHHFHHGHHFFHFGGGHHHEGHDGHHGHGHFHHHECGCBCHHGFHHFHD1GFHEFHEF?GDCFFEFE0A@;@>BD/9BFBBBBFDFFFF99D=?>DDBFF-AFFEBB9BBEFEFAFFF//-@---;;FBBFBFB///;99999BA9
+@M01368:8:000000000-A3GHV:1:1104:13832:4398/1
+CACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGACAAAAAAAAACACACAACAACCAACACCCAGTAGACTAGTGCGTC
++
+AAABABCAFFFFGGGGGGGGGGHFHHHHHHHHHGFFHHGGHGGGGGHHHHHHHHHHFHHHHGHHHHHGGHGHGGHGGGGGGGHGFFGGGGDGGHHHHGGGGFGGGGGCFGGEGCDGGGGGGGGGGGGEGF?;BFFFFFFFFFFFFFFFFFF:FFFFFFFFFFFFFFFFFFFFFFF/FFFFFFC.;BFEAFFFFF;@FFBFFFFEF?/FFFFE----:...:...9....9.9...:.9//9////;/9-.-
+@M01368:8:000000000-A3GHV:1:1104:23670:4161/1
+ATTCAATTGTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCC
++
+AAAABFFFFFFFGGGGGGGCGBBGGHHHHHHHHHGHHHHHHHHHHFGGHHHHHHGGFHHHHHHHGGGGGFHHHGHHHHHGHHHHGHHGGGHGGGGHHHHHGHHHHHHEGGGFHHHGFFDGEGHGHFHGHHGEGGGHHBGHGGHGHGGGGG/@FCDFDGFHGGGDFFHFGFFGGGGGHHHHGGGGGGGEGCDG?GGBFFFEE00BFFGABBBAFGGGEGEA.9FFF/./;BFBF./AAF/BFFBBF/F/BFB
+@M01368:8:000000000-A3GHV:1:1104:24927:22253/1
+AGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTAT
++
+AAA?AFFF3DFFFGGBGFF3EAEEEHFHHFHHHGHHHHDGHHGAEFGHHHGFCHHGHHHBGHHHAEGGHGGFHFBFHHHHHHHHHHFHH1EEHEEHH1FFDEEFCGHBGHHFHEHHHHHH1FCGHHHHEEFGEEGFFCHHH11>GHHF/FG2DGGCGAGGHGGGG@@@BEFFF?@@@FFEFFFFFF?@@FB@BB@FFFE=;==---A9EFBBB/;E;A9B/B/FFFEF/B///;/;9/A/;/9BFFFBFBB
+@M01368:8:000000000-A3GHV:1:1104:4705:7727/1
+CTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGG
++
+BBBBBFFBFFFFGGGGGGGGGGHHHGHHHGHHHHH6GHHHHFFGGGHHHHHHHHHHHHHHHGGFGGGEGGGHHHHHHHHHHGHE3FGGGGHHHHHFHHHHHHHHHHHHGGGGGHHFHFCGFHHGGGGGGGHHGGGGHHGGGGGGHHHHGGGADCHHHHGDGGGGGGGGC@DGFHEHHHHHHGHHHHGFGDEGFGFFGGGGCFGBEGFGGGFG;C.BFFFFFFFBFBFFFF/F?.AFFF/BFFEFFFFFEFF
+@M01368:8:000000000-A3GHV:1:1104:7756:4776/1
+GGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGA
++
+CCCCCCFFFFFFGGGGGGGEEFHHHHGHGHHHHHHGGHHHGGGGGGHHGHHHHHGHHGHHHGGFHHHHHHHHGHHHFHHGHHGFGGGGHHHHHHHHGHGHFFHFHHHHHHGGHGFGFHHHGHG?FGHHHHHHHHHHHHHHGHGHHGHGGCDGFFHHHHGHHHHHGHHHGFHGHFHGHGHGH/@CABFFFFFFFACAFF?BBFFBFD-@-.D>FFAF.F.:9---;AADFFFFFBEFFF:9FFFFBBFFFF/
+@M01368:8:000000000-A3GHV:1:1105:11310:21761/1
+ATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTTCACTTT
++
+CCCCBFFFFFFFGGGGGGGGGGGHHHHHHHHHHHHGHHHHHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHGHHHGHHHGHGHHGHHHHGGHGGG=FFGEHHHHHGHFGGHHGHHHHHFHHHHHHHGGHHHHHHHGHEHHGHHHHHGGGGF9AGE?DEGFFGGGGGGGGGGGGGGFFFF/9FFBFFFFFFFEFFFBFFFFFFFFFFFFEFFF0
+@M01368:8:000000000-A3GHV:1:1105:11578:14676/1
+ATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTC
++
+CDDDDFFFBFFCGGGGGGGGGGHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHFGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGHHHHGGGGGGHGGHGHHHHHHH;CHHHHHHHHHHHHHHHGHGGGGFGGGFGGGGGGGGGGGGFGGGEGGFFFFFFFFFFFFFFFFFFFFFFFFF/FFFFFFFFFFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1105:13575:19255/1
+TTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGTTCCCGTGAGTGGTTAATAGGGTGATAGGCCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+AA1A1DFFFFFBGG3A111FFAEGDDBGFDHF00F01BBA00BFGEHFBFFA1FABB0FAE?CFHF1BGFHFB0011F121E//>>1F10>B?EFHGCC/?/BFG/EEGFFEE//BCFDE0?E@@B/?11</?//<@?/F<<<A-<FBGH0.00=G0<<C//./0;;GC....<C.=.00;;BB./:.900////.C000;0090;..//000;C/;;/B/9BA9A9-AEEFF?B---;B99//9/;A//9
+@M01368:8:000000000-A3GHV:1:1105:15502:11453/1
+GTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCTGTCTCTTATACACATCTC
++
+A3AAAFFFFFCFGGGGGGGGGGHHGHHHGHHHHHHHHHFGHHHHHGGGGHGHHHHHGFHHHHGHGGGHHGGHGGHHHHHHHHHHHHHHGGGGGFHGHHHGHHHHHGHHHHGGGGGGHGEGFECHEHGGGGGGHHHGADFHHGGGGHHHHH<ECGGGGHHHHGGGGGGGHGGGGGGHHHGHGHHGEHBFFFGFGEGGGGGEDEGF0C;;BFFFGGGBEFFE/FFFFFFFFFFFFFFEFFFFFFFFBFFFBFF
+@M01368:8:000000000-A3GHV:1:1105:16787:9771/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+AABCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIHHHHHDHHHHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHGGGHHHGGGGGGHHHGGGGHHGGGGGHHHHHGGGGGGHHGHGGGGGGGEEGEGFGHHHGGGGFFGGGGGGGGGGGGGGGEG?G;:EFFFFFFFFF:AEFFFFFFFFBFFFFFFFFFEFF/
+@M01368:8:000000000-A3GHV:1:1105:17564:15723/1
+TATGCTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAA
++
+EDCCDFFCEEDCGGGGGGGGGGHHHHHGFGHGGHGGHHHHHHHHGHHEHHGGGGGHHHHHHHHHGHHHGHHHHGGGGGHHHHFFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHFEHHHHHHHHHHGHHGHGGHGGGCGGGGHHH1FGGGFGGFGGGGGGGGGGEFGGGGGGGGGGGGGGGGGFFFFFFFFFFAEFFFFFFFFFFBBFBBFFFFFE1:BFFB0
+@M01368:8:000000000-A3GHV:1:1105:18108:12091/1
+TAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACAC
++
+CCCCCFBFFFFFGGGGGGGGGGHHHHHHHHHHHHHGGGGGGFHHHBFGHHHGGGGGGHHGGGGGHHGFGGHHHHHHGGGGGGHGHFGGGGGGDGEGEFGCHHHHHHHHHHGHHHHGEDHHHGGGCDGGGGFHFHGHHHGHHGHFGHHHFHHGFHHHFHHGGHFHFHHGB0CGHGFHCBGGGGEDEE9ADFEFFFGFBFGFFGGFFFFFGGFGFFFFFFFF/A?FEFFFFFEF-A.B//;BFFEF//BB///
+@M01368:8:000000000-A3GHV:1:1105:18331:16683/1
+TCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTA
++
+BABA?DFFFFFFGGGGGGGGGGHHHHHHGHGHHGGGHHGHGGGGFFHHGHHHGHHHHHHH3FGHHGGGHGGHHHHFHHHFHGHHHGHHHHHHHHHHHHGHHHHGGCGGGHHGHHHHHHHHHHHHHFHHGHHGHGHEFGGGGABFFFGBEGGAFFFFFFFFFFFFFDDFF?DFFFFFFFFAEFFFFFFFFFFFFB;9FFFFFEFFFFFFFFFFFF?FFFFFFF/BFFFFFFFB.DABFFFFFFB.//:FB//
+@M01368:8:000000000-A3GHV:1:1105:20577:18421/1
+GGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCC
++
+ABB@3>AAFFFFFEAGGGFGGAA6FHDGGCGFHFFHFHFHHHHHGDDDFFFHGFFHGBEGEGHHHFFFHGEEAEGHHHHHFHHHFHGHFEDGGEGBEAGEFHHFFHHHHHHGGHHHGHHGBGHHFHHFGHHHHG?CG?AFHH1FHHHGHFHHHF?DGHFFHCGAGEFHGCBBBB?BFFF?B-B.9/BFFFFFB=-AD?..@FFFF@@-@@?AFD.FFFBBEEBD9/:FFFFFBB/:FF9BF/BF.BBFF/:
+@M01368:8:000000000-A3GHV:1:1105:21099:2895/1
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTT
++
+CBCBBFFFFFFFGGGGGGGGGGGGGFHHHHFHGHHHHHHFHHHHFGFHHHHHHGHHHHHHGHHEHGGGGHHHHHHHHHHHHHHHHHHHHHHGGHGGHHHHHHHHFHHHHGHGHHHGGHHHHHGGHFFGHGCGGGHGHHGHHHFGHHFHH/FGGGHFGFEGGCFCCD;B@DFFFFFFFFFFFFFFFFFFFFFFFFF;F.BEFADFFFF.AEFFFFFFE;D.;:B00099:09BFBFFBFF.0:000BFFBF0
+@M01368:8:000000000-A3GHV:1:1105:26469:19245/1
+TTATGATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCAAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATG
++
+BAAAAFFFBFFFGGGGGGFFGGHHHHHHHHHHHHGGHHGHHHGGHHHHHHHHHHHDEGGHGHHHHHGEDHFHGFHGGHHGGHGGEHHHGHHGHHGHHHGGEGGGHGHGHHHHHHGHHHHGHGGGGGHFHGGGGHHGGGGCDGHHHGD<EHHGGGGGHHGHH?EDCCDHHHHDGFFGGGHGGFCGGHHHHFG.CFGGGGGGGGGGGBFGDEG.AFFG;AFFFFEB?/A9BBBFFFFFFF/9FFFFBDEFFFF
+@M01368:8:000000000-A3GHV:1:1105:7169:17145/1
+AACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAAAGTGT
++
+CCCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHBHHHHHHHGGHGGHHHHHHFHHHHHHHHHHHHHHHHHHHHGHHHHHGGGGCHHHHHHHHGHHHHHHHFHHHHHGHGHGHHGGGGGFGGHHGGGGGGGGGGGGEGGFGGGFFFFFFFFFFFFFFFFFFFFFFFFFFFDFFFFFFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFFFFFFFF-9@DDBFFFFFFFFBBFFF0
+@M01368:8:000000000-A3GHV:1:1106:15481:16176/1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTT
++
+ABBBBFFFFFFFGGGGGGGGGGHHGHGHHHGHHHFGHGFGHFEHGGHGGHHHGHHHHFGHGGFGFFHHFHHHHEGHFHHHHHFGGGGGHGGGHGFHGHGGGGGGHHHGGGGHHGGGGHHHGGHGGGGGGHHHHGGGGGCFHGGGCDGHGHHHFHEHHHHHHHHHEEFHHGG:C:?0<EFGBFGGGGGFE.BFGEFFFGFFGGGGGGFDEF/FFGFFFFFFF;BBFA;.:EFFE:AAFEF.BFFFFF;9FF.
+@M01368:8:000000000-A3GHV:1:1106:17389:18671/1
+CCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGGCTTTGATTC
++
+3>>A@FFFFFFFGGGFEECFGGFFB5GBHH5DFH5GBEEAEFHFHHF3F3GHFHHHEF3GAEHBGFHFFEFFHHHHFFB31FGGEGFHGEHHHHHHHHHHHHHHHHHEEEEGHHHFFF3GF3FGF44BBGEHHHHGG2B/BGGHE</ECDFHHBF1DGBFBFGFH<1GHGDGGFDFE0/<--;-9./BBED;BFBD/BF9BFFFDBFDADD;FFF?->;B=.9.;.BBFFF..;A;/B/;B//;;//BBF/
+@M01368:8:000000000-A3GHV:1:1106:22927:3863/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGACTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAA
++
+A>ABAFA?D@AFGGGGFGGGFGFHHHFFH4BCBGHHHHGFFF3G5BF3322EEAFHHHHHHAB5GHFHEHFHHH3BEEHFGF5@13FDF3GDGFHHFGHHHGHHHGFGGHHFCG//?/EGHHHG3F4BFFGHHHEDGFHHB/B/?FBF<@-9?BDEFFF?B--?DFFFB9FA>B;A.BFDB?AB.--@;-.FFAEFFFF9AE;DDFFFFB/9BFFFFFFFB:BF/BB/BFF//FFF-=--.99=--.9///
+@M01368:8:000000000-A3GHV:1:1106:23625:4236/1
+TAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTA
++
+@?AAAFFBFBFFFGGFGFGGGEFCGGHHHHFGHGHFHGHHHHGGFGGFGHHGHGHHHHGHGFFHHGGGGGHHHHHHHHHBFHHEFHHHHHHGF?FAGHGFHHHGDGFHHGGGHGHFHHHGHHHGHHFHHGFFGFHHHGHHHHFFHHHHH/FGHHHHGHGHG<C???B=@ABBFEF@=-AFFFFFFBFAFFDFFFFA?AFFCFFABEFFFFFFFFF?FFFDFFBFF;FFEFFEFFFFFFFAF///9FF/BB/
+@M01368:8:000000000-A3GHV:1:1106:26031:14826/1
+GATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGTCTTCTGCTTGA
++
+ABBAAFFF@FFFGGGGGGGGGGHHHHHHGHHHHHGGGGGHHHHHHHHGHGHHHHHHHHHHHGHGHFHFGE?CGDGGHHGGGGGGGHHHHGHGGGGGGFGGGHGHGGGGGGGGGGGGGGGGGGDGAFFGFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFEFFB/9FFBFFFFFFFFFFFFFD@D=BEFFF;FDDB////B=CF-.;BAFFFFFF;;BFE/BFFFFB:
+@M01368:8:000000000-A3GHV:1:1106:27607:15990/1
+GACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGACTTCTGCTTGAAAAAAAAAAACTACAACCCACGGACGCA
++
+BBBBBFFFFFFFGGGGGGGGGGGGHHHGGGGGGHHHGGGGGFCEGGHHHGHHGGGEGGHHHAFGGGGGGAFG//EGHHHHCGEHHHHEEHHFHGHFHHGGEF/FGGC?FDFH2DHHFFGGFGHHHHGGHHFGHHGHGHHGFHDHBGBBGHHFHHGGCCDC<=D<DGHHC;CGFCCFBECDG?FGGA-;EB9FBGFFBBF>DFFFE?FFF/--;;9/:BFFFBA///9----;B.//////;...---9---
+@M01368:8:000000000-A3GHV:1:1106:6455:17124/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACG
++
+BBBAAFABDBBFGGGGGGGGGGHHHGHHGHHHHHHHHHGHHGHHGHHHGHGGGEGHHHHHHHHHHHHHGHHHGHHHGGHGGHHHHHHHHHHHHHHHHHHGHHHHHHHHGHHHHHGGCFEHHHGFHHHHGHHFFH?GGHHHHGHGHGHHCFGGGGGGGFFFFFFFFFFFFFFFFFFFFADFA?.FEFAFFFEFFFFFFFFFFFFDABFBBFFFFFFFFEFFBFFFFFFFFFFF/FFBFFFFFFADE>BFFF9
+@M01368:8:000000000-A3GHV:1:1107:14451:26748/1
+GTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGA
++
+BABBBFFDABBBGGGGGGGGGGHGHHHHGAGHGGGGGHHHHHHHHGHHHHHGGGGGGFFHHHHHHHHHFHHHHHGGGGCHFHH3FEHHGCGGGDGHHHGFGGHHGGGGHHHHHHG/DGGGHHHHGGGGGCCHGG?CGG1GHHGHHHHBGHHHFHHGHHHHGGADAD00ECEGHEFHHFFAEFFFFFGGFBFBFFFGFFG.;B/99;BCFGGGGEFFFFFFEDA./:ADEB?FBFFFF;FFEBFBFFB./9.
+@M01368:8:000000000-A3GHV:1:1107:18714:24788/1
+GTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGA
++
+BBBCCFFFDEDEGGGGGGGGGGHHHHHHGGHHGGHGGHHHHHHHHHHHHHHGGGGGHHHHHHHHHHHHHHHHHHGGGGGHHHHCFGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHHHHHGHHHHHHHHHHHGHHHHGGEGEGCCEGGHHHHHHG:CAFFGGGGGGBFEFGGGGHGAFFGGFGGGGGGGEFFFFFFFFFEF/EDDFFFFFFFFFBFFFFFBBFFBBF/
+@M01368:8:000000000-A3GHV:1:1107:21355:8333/1
+ATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATG
++
+ABCBBFFFFFAFGGGGGGGGGGHHHHHHHHFHHHHHGGGGGHHHHHHFHHHGHHHHHHHGGGGGHHHHFFGHGHGGGGGGGHGGEGGGHGGGGHHHHHHGGGGGGHHHHGGGGGGGHGGGGGGHGHHHFHHHHHHHHGHFFHHHHGGHGEGHHGHGFHHFHGHCEFHEGHGHHHGHHHGGGGGGCFFFFBFGGFGGGGFBG?FDGGGEGFFFFEFFFFFFFFFFFFFFFFFFFFFFFFFFFFFBFF.AA/9
+@M01368:8:000000000-A3GHV:1:1107:22864:15712/1
+AATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATG
++
+BBBBBFBBFFFFGGGGCEGGGGHGHHDGFHHHHHHHHHHHHHCHHGHFGBGDFGE?GHHGHFBHHFHHHHHHHHHGHFGFGHGHHGGC@DCFGHHGGGGGGGHHHHHHGGGGGFGGGGFFGGGGFADGFEFFFFFFFFFFF9;FFFF/BFFFFFFFFFFFFFFFFFFFFFFFEFFFFFFEAECDFFFFFFFFFBFFFFFFFFFFFFFFEFBFBFFF/FFFDF-;-9;E@>-9DFFF/FFBF;-.:;.9A//
+@M01368:8:000000000-A3GHV:1:1107:24817:14233/1
+CTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACAT
++
+3AABABFFBFFFGCFGGGGGGGHHHFGCFGGGFFGHHCGHHHGHGHGHBFFHHHEDGGFGFGHHFFFHGGEGHFHHGHFHGFFHHHFGHHHFHACECEHHHBGFHGFHHHFHHF4GFHFHFHEHGGE/EG:A-CFGGFGADGGGGFGGGGDAAAADFA.-AFFECFDAAFFFFEFFFFBFF;D;BFFFB/;BFFFFFFFFFFFFFFBFFBF/;//;BFFFF?FFFFFFEDAFFFFFBF//:BFBACF--9/
+@M01368:8:000000000-A3GHV:1:1107:24830:14440/1
+AACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACC
++
+ABBBA@FFFFBBGGGGGGGGGGHGHHGHHGHHHGGHHHHHGHGHHGDHHHHHHAGGGGFHHGHHHHHHGHHHHHHHHHHHEGAFGFHFHHHHGEGHHHHHHHHHHHHHHHHHGGHHHGEFEGGHHGHHHHHGGHGFHH/?GHHHHGFGHGFHCGGBBDAFFFEFFFFFFFFFFFFFF=CDDADDFFFFEF=BFFFEFFFBFFFFEEBF./:FFFFFFFFFFFFFFFFFFFEFFFFFFFFFFF/BFBEFFC-
+@M01368:8:000000000-A3GHV:1:1107:26478:23602/1
+GCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATCTGTCTCTTATACACCTCTC
++
+1AAAAF1B13BBBEGGGFGGGGGGHHDB1BGFHHHFGFGGG0F00BGBGFGGF1GBGB1BGCGAEE/FGFHGHFHHHHHBFF1B0FGGF//F//FGFGFFF/1@B1DFHHHGGEFEDHFDFAFF0B//</ECCC>1FDD1GFFHHDF?1BD>GF/GCAC0C@?@-;99BBB->@--;-B//99B--9-BF=A--A-:A----9AA9AFBFBBB?E@BBFFFFFFFBFFFFFBFFFBBFFF//B/////-;9
+@M01368:8:000000000-A3GHV:1:1108:11059:23181/1
+GTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGAT
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHHHHHHHHHHHHHGHHHHHHHHHHHHHGHHGGGGHIIIHHHHHHHGHHHHGHHHGGHGGHHHHHHHHHHHHHHGGGGGHHGHHHHHHHHHHHHHHHGGGGGHHHHHFGHHHGGGGGGHHHGGGGGHGGGGHHHHHHGGGGGGHGGHEFGGGGGHGGG-ECHHHGGGGGGGGGFGFFGGGGFGGGCF?EFGG0;BFFFFB?9AAFFFFFFBF;BBFFBFFFFE?F/
+@M01368:8:000000000-A3GHV:1:1108:12233:13498/1
+TAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCCTGTCTCTTATACAC
++
+BCCBAFFBCCCCGGGGGGGGGGHHHHGGGGGHHHHHHGHGHBGFHHHHHGGGGGHHGGBFGHHGGGGGGGHHHGGGGHHGGGFHHHHHHGGGGGGHGHHGGGGGGGGGGGGGGHHHHFHHHGHGHHHHHHGHGHHGGFGGGDFFGGHHHGHGH/<GHHFGBGFHFBGHHHGHHGEFHFHFGBF0BFGGGFGGGGGEFFF;A?EEG?CFFFFF0:BEFFFFFBFFFFFF0FFEFF?EFFFF0BFFFFBBB00
+@M01368:8:000000000-A3GHV:1:1108:14328:14751/1
+ATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACA
++
+BCCCBFFFFFFFGGGGGGGGGGHHHHHHHGHGHHHHHGGGGGFHHHFFDGHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGGGCFGHHHHHHHHHHHHHHHHHGHHHHGGGDGGFGGFGGHHHHHH>FHHHFHGHGHHGHHHGHHBA<CGFHHHHHHHHHHGFHHGDDEGCEGGGGEEFBFGGGGFGGGB0CFF:FFFFFBBFFFFBFEFA.BFFFEFFFBF/BF/FFEFFBFFF/
+@M01368:8:000000000-A3GHV:1:1108:16350:22621/1
+TTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATG
++
+AAAACFFFFFFFGGGFGGGGGGHHHHHHGBGGGFGGGHFGGGGGHHHHHGGHHHHFHGGGGGGHHGFHHHHHGEFHHFFHHGFCEFHHHGFF?GHHEE@ECFHHEGGGGBFFEGGGHFDHHGFG/BFEHHFCDGGGCDEGGGCGFFFHHHFEGHFHHHHGHHDGHHHGGHDED0CE;CFFFFBFF/;CBFFFGG0/FFF0B0:BB?.;BFF0FGFBFFFFFEFE;ADED.;BE.99FAFFFFFFF/;EFF/
+@M01368:8:000000000-A3GHV:1:1108:21791:23272/1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTA
++
+3ABBBFFFFF@FGGGGGGGCGGGHHHHHHHHGHHACGDAGFEEHGGHHGHHHHHHHHHHHGGGGGGHHHHGFHFGHGFDDGFFFGGFGHHFF?FEGHHGGGGGGHHHGFFDHHFGG?HEFGHHGGGDDCGFFC?ECCFGDEFGGGGGGFHHHHHHHEFHFCGHHGEGGGGD.:.A;CECAFFFFBFF/;EFFBFFBFB;;BFFFFBBAA./BFFEBB//BFFFFFFFDFFFEEFEFFFBFBFBBFFFFF./
+@M01368:8:000000000-A3GHV:1:1108:23314:26089/1
+ATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTG
++
+BBBBBFFF?FFAGFBFGGEGGGGHGHHFHHHGHHGFGGFHHHHHHHHFHHFHHGHHHGGGGGHHHHFFEHHHGGGGGGHFHGEEGF3FEFGHHHHHFFDEEEEHHHGEEGGGGGHFGGDADGFFFFFHHFGHHHFGBHGHHGBCEHDEDDGADCFFHHHGG/:GCCCGHFGHFFGG0CGFGF.FB/9;BFBB0FFBFG0A-..;C:E/.A9.FFFFFFFF9BFFFFFFBFBBB./:BFFF/F;AA?F////
+@M01368:8:000000000-A3GHV:1:1108:25084:18127/1
+TTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGAGATAGACCTGTGATCCATCGTGATGTCT
++
+CCBBCFFFFFFFGGGGGGGGGGHHHHHGHHHHGFGGFHHHHGHHGGFHEHHHCGGGHBHHHHHHFHHGHHHHGGHHGGHGGGHHHEFHHHHEHGHGGGCFHFHHHHHHHHHHHGHEFGDEGGGHFHHCGGHHGGGGGFGHHGGEGDFHEGG/?GFHGHDGGGGGHHHHADFGGGGGEGCGGGEFGHHFEBFFGGG?GGGGEGGFEFAA?.0:A0;BFFFBFF/;9BFFFFEFF9FBFFB/F/.;FFFF/BB
+@M01368:8:000000000-A3GHV:1:1108:7626:10048/1
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGAA
++
+CCCCCFFFFFFFGGGGGGGGGGGHHHHEFEFHHGGGGGGHHHGEF?GGGGGGHHHHHHGGGEGEHHHHGGGGGGGGGGGGGGHHHHHHHHHHHHFFCGHGHHHHGG/BFGDGG2FFHFHGHH0FHFGFHHHHFFHHHHHHHGG<FHHHFGHHGGGGFHHHGGGGGGHGGHGGGHHHHHHFGGGGGGGFFFGGFGGBFGGGGGGGGGGGFGFFFCFFDFFFFFFFFF;./;AAAFFFFFFAFABBFFFB/;;
+@M01368:8:000000000-A3GHV:1:1109:11270:12255/1
+AATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAGGTAGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTT
++
+CCCCCFFFFFFFGGGGGGGGGGGGHHHHFFFHHHGGGFGGFFHGEGCHHGGGGHHHHHHGGGGGGHHGHGGGGGGGGGCEGFCHHHHHGFHFHHHHGFHHGGFHGGGFD/EFGEFFDGFHHGEFCEHFFGHHHGHHHHHHHHHGCGHHHGGFGHHHHGHEHHCFFADGHHHD?CG.CGHBCBFBFFGGFFFGFFFFF.CFBFBCFFFFGFFFFFGGGFFFFFDFAFFFFFF-@DBFFFFBFD---.;BAA.
+@M01368:8:000000000-A3GHV:1:1109:19224:11655/1
+AAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGCATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCTGTCTCTTATACACATCTCCGAGCC
++
+BBB@A4FFFBBBGGGGGGGGGGHHHHHHHHFHHHHGFGHGGGFFAGFHHHFHHHGHHHHHHHHHHHFHGGHGHHGCFFGHHHGHHHGHHFHGGH3BFFGHHGHGEFFH/EG@-CFGGCC@-;BD?FGGGGGG??FGDAGDFFFFEFF@BAAFEFFBFFFFF?FD9BBFFFF/FFFFBFFFFFFF?FFBFFFF/FBBFFBFFFE?F;@B//AFFFFFFFFF//;BFFEF.BFFFB/;F/99/FBFFBDCF;B
+@M01368:8:000000000-A3GHV:1:1109:21978:9490/1
+GGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCAGTT
++
+?A3AA?DFFFFFGGGGGGGFFGHFGCEGGFHHHHHHHHHGHCBGFEGGHHDEGAFGHGHFGDGBCGHHHHHFHHGHHHHHHHGHHHH1E?EGGGHHHHFGFHFHHHHHEDHHGHH@GGHGHHCGG?CFGFGGGGGFGB.BFGGFFGGFFFBDDBFFFFFF9-;DEFFDFBFFBB.EFF;BFBFFFFFFFFFFFFFFFFFFFFFFFFF/B9/FFFFFFFAFFFF--99AFFFFFFFA;;;FF..9//;/;;/
+@M01368:8:000000000-A3GHV:1:1109:22910:4079/1
+TAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTCCACTTTAGCTA
++
+CCCCCFFFFFFFGGGGGGGGGGHHHHHHHHHHHHHHGGGGGHHHHGGEHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGFHHHGGGGGGGHGGGGGGHHHHHHHHHHHHHHHHHGGHHHGGHGGGHHGHGHHHHHHHGFHHHHHHHHHHHHHHHHHHGGHHHHHHHHHHGHHHHHHGGGGGGGGGGGGGGGGGGGGFFGGGGGGGGGGGFFFFFFFFFFFFFFFFFFFCCDFFFFFFF0BFFFFFFF0
+@M01368:8:000000000-A3GHV:1:1109:24217:19077/1
+AAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGCCTTTGATTCCTGCCTCATCCTATTACTGTC
++
+>AAA3BDFFFFDGBFFEEGGGGHHGHFHHCFHGHGHHHGF3BFGFHGFEFHFHGH3EGFC1EEGBFGBHFGGFFHHHGHFHGHHGHGGHCEHEBCFF3ED3@GH4FDEG12FFHFFHG/G3FGA/@EFEFCG33FFGBBGHFHH/?BFBGFGFAGC2C/@-;@-;BFFEFADF?DFFFFFF?;AFFA;AD;..FEFFA--;9;D.9BFFBE?;.;///://///99//BB/9;F./B//BBFB9////99/
+@M01368:8:000000000-A3GHV:1:1109:25237:11722/1
+CCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATATCGTATGCCGT
++
+AABBBFFFFFBBF5BGGFGABGHGGAEFGFHHHHFHCHFHHBFGGGEHBGGHFFFFGFAEF5FHH?EGGF5AEG3?EBFHD?C/EFHFFEGEE?CFGGGHHFHB3EEFG?EEGHCFGGGGGGGEC<CDFHHHHHE.FD11FFAGBGD.DGHEA<.<<0<EHAHCFHHF./;CC0GFH0::0CFGG0FBFD;9/90BFF0CBBFGB09;B:0;CFF0.-;@AFEEF--;AFFBF/99D-;.//.../9;B-.
+@M01368:8:000000000-A3GHV:1:1109:27103:7153/1
+GTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGCTGTCTC
++
+33>A?FFFDFBFGCG4EGFG??GACFGGHFHCFHCHBECDEFCEGHHHHHFFGGF3AFFHHFGEGCGHHGEHGFGHHEGG?EFHHH?EGGHHGGGGHHHHHHEGGGGGHFHHGFDDGGACFCC@?/FDDGHHHGHEFFHHH0FDHHFFEDCD.<GGEHGF0CHHHF/CAGC000CCGFHFGFGFFG?:CB990;F09;FB0BBGGGGGG?;A9EBDEFA///;FF/:F?BFBBFFBFFFF///;/9B;///
+@M01368:8:000000000-A3GHV:1:1109:8763:7859/1
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGCTTTATGC
++
+BABAADFFFFFFGGGGGGGGFBGFGHHFBHHHHGGHHGGEHGDHHHFGHEHHHHGHHGGGGAGHHFBHHGHFHHHHHHHHGGGCEFGFFFFEHHH?FFG1FFHHFEGGGHGFEEHHHHHGGGFGGGHHHHGGGGG/C/FG-<A<GFHHFFCGHHFHGE0<<CGHHHGCHG.CCCCCE00BBFGFFG.BB0FFBFBCF0;CBFFFEEGBBBFFBF/FFF9BF/9BAFFD9AFEDAA.A/BFFFFFFFFFEB/
+@M01368:8:000000000-A3GHV:1:1110:12808:18367/1
+AATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCCTG
++
+BBBBBFFFFBBFGGGGGGGGFGFGHHGGGGGHHHHHHHHGFHHGEGGGHHGFGHEEGGHHHHGHHGFFHHGGGGGHHHHGHGHGHHHFGGFHHGGGGGHHFFFGGHHHE?@EGGHFHEGGGHHGGGGHGEFHHGD?/>CFHHGDFGGGGGEFGC?EGHHHB0CGHHGCGHHHHBEHGHH.::ACA;FECFGGGGGFFFEFGGGGGGGFFBBBFGBFFFEFFFFBFFFFFFBBFBFFB9..AF?FFFFFFF9
+@M01368:8:000000000-A3GHV:1:1110:14751:26540/1
+TAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACTGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGTTGTGCACGCGATAGCATTGCGCGACGCTGGCGCCGGCGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTG
++
+AAA?1CFFFFADGEEGFGB1112DGDGHGFGHHCG/ECEBGGHDFGHHFHGHEB1BCGFFE2EGHHGHFFFHHBFFHEFCGGHHFHHHHH111BFFHGHEHBEHGGECEFHGFHFGGDBBGHHBHHHH0GH22FGHGFFFH1BFCG0F@FGG11@GDHFG1D/1FGFHH/FCG.>0><-<@CCFFG.CC-@C?C9FFF0C---;------;9----9-9@-AAFF9B9---9-/;B9BF/9BB//B/;///
+@M01368:8:000000000-A3GHV:1:1110:15519:10008/1
+CTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACC
++
+BBBBBFFFFFFFGGGGGGCBGGE?GGGHHHHHGHHBEGGHHGGGGGHHHHHHHHHHHGGHHHHGFGGGGHGHGCFGHHHGGGCGGHGHGGGGGHFGGGHHHHHHGCEFGGHHHHGGGGGGGHGG/CEGHHHHGFHHHGFHHGFFHGHGHFGGEGFDDGGBCGHHGFHH/CHHHHGHGHF0CFGGGGGGGFFFFFBFFFFFFGFFGGF?DGEDEEFEFFFF?FFFFFFFFFFFFFFFBFFF.BFFFBFBBA;
+@M01368:8:000000000-A3GHV:1:1110:16559:7507/1
+CATTCAATTGTTATTATTATGTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAACTGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATC
++
+ABBBAFFFFFFFFGGGGGGGFGGGGAGHHGCHHGHHHHHHHHHHHGHHGHHHHHHHHHHHHHHHHFGGGHHHHHHHHBDHHHHHGGHFEEGHGGHHHHHHHGHHHEHFGGGGGGHHHF33FGHHG3GDDGH//EEGHHFFBF?GHHFCC@DGFCGGB?DGHAFGGHHGFH0E??<@DGHGGCFGGF?DGGGFFGGGGGGGG.C/0BBF?FBBEGG0FFF.AA9;B9/E////99;;:.//:FFFFBBF//9
+@M01368:8:000000000-A3GHV:1:1110:16700:6843/1
+AAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCTGTCTCTTATACACATCTCCGAGCC
++
+BBBBBFFFFFFFGGGGGGGGGGHHHHGHHHHHHHHHHHHGGGGGHHHHHGGHGHGGGGGGHHHGFFGHHGGGGHHHHHHCGG@FGHFHFEGGGGGGHGGGGDGHHHHHHHHHHHHHHGHHGHGHHGGGGGCGHEHGHHHFHHHFF.DGHHHHHHGHHHHHHGFGHGCGHGHHHHHHHHGHHHCD?:A::FCDGEGFGFFBFGBFGGGF00CBFFFF/BFBFFFFAE.FBBFBFFFFB/BFFBFFF/ADCAD
+@M01368:8:000000000-A3GHV:1:1110:18014:7856/1
+ATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGGGATAGACCTGTGATCCATCGTGATGCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAAAAAAAAAATAG
++
+AABBBFFFFFFFCGGGCGGGGGGHHHHHGFHHHHHHGHHHGGGGGFHHGHFGGHHHGGFGGGHHGGGGGHHGGGGHGGHHHGGGGGGHHGHGDGGGGGGGGB/A<GFHFHHHGHBBGFEGGGGHFFFEF/EEGGHGGFEHFHHBA.<ADFFHFHB/CCGHFEFHHGHGEFFGGGGGFFFGGFGFFBFFGGBFGG??DGG?@9-ADFFFFB/@BD;./BFE?BFE/>99FE//BBFFF.9/FF?DA=@9./9
+@M01368:8:000000000-A3GHV:1:1110:23303:11846/1
+ACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGTGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTC
++
+3ABB?FAB?DAAGGGFBGGBB5AFFFGFHHGGGEGHHHFHHF3EGFHHHHEFHHGGHHHGH3EFHHHHHBDGHHE?ECHGHGHHHHHHFHHHGHHHHHHHGGHGGFHHHFHHGFFHHFEGFHHHHHHEHHFDAGHHHH/BDDFGGH1FDBGHHHHHHHCGHHHFH?0CGCF>CC=@--AFBFFB?=BFDFFF//FDB;-9A-AD-.A.A=?-9-:B/AEB/BFF.A;DDFFFBBFFFF/BBFFFFBFF9B;
+@M01368:8:000000000-A3GHV:1:1111:13195:14562/1
+ATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACCTGTCTCTTATACACATCTCCGAGCCCACGAGA
++
+ABAAAFFFFFFFGGGGGGGGGGGHHGG4FDFGFGGCGGGHGHG?EGHEGFFDHFHHHHGGFE@EHHGEEEGFCCEFFGFG/EHHHHHBFBGGHFHFHEHGHEFGGGED/EFDEFFEHHBGHHCFFFDFGGHHGFFFHHHHGFG>0<0DGGFHBGHFBDFGHGFFGGAGHHGCGBHFFHHHFFFBFGGGGF/:FFFCB9F9FF0FEFE?FF0BED-D.//BF9//BBFF/BFFFEFFFFED-DCFF?.:BFA
+@M01368:8:000000000-A3GHV:1:1111:14287:20817/1
+GCCAACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTCATCGCACCTACGTTCACTATTACAGGCGAACATACTTATTAAAGTGTGTTAATTAAT
++
+>>A3>AAAACFFFGFGFGGGGGHGHHHHHHHGGGGGHGHFFCGHHGBGHFHHHHAGHHHHEHHAGFFEHEAE?GHHHHEGFFFDGHGHBFFHFHHHGHGHGHBECG@@@EHGGEGCGGGGFFGGGG?BGGGGGG.-C.FEDCFFFEFFFAF/99BEFA.:9BFB/9FFFEFFFFFFEFFF/FBBFFFFFFFFFFFB//;.@@//;DFFFF//BBFFFBF;A;DF=>B//;9B//B/;/;9//9//;B/:B9
+@M01368:8:000000000-A3GHV:1:1111:23624:14516/1
+GTCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGGGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAG
++
+3>3AAFFFFFAFGGGGGGGGBGHHHHHHGGHGGHEHGHADFHHHHEGGGHBGHFFHHEHHGHFHGG5FBEEGEGHHHGHHHEFDGHHFFGFGGHHGHHHGHBHGHFHFHHGGGGFCFBGFGE?GFBECEGDGHEHGDGCGHGC/DF@GHGFFCGGGGFFFFDD?@C@GFEC?-ADHFFHBGHFBHFG0CC//.;B0/CA.;AA.;@.AB/9BB/A/.AFFFE/BFFF///9B/FBDE9/;99/B/BFFEF/
+@M01368:8:000000000-A3GHV:1:1111:7437:24508/1
+ACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTGTCTCTTATACACATCTCCGAGCCCACGAG
++
+CBCCDCFFFFFFGGGGGGGGGGGGGGHHHHHHHHHHHHHHHHGGGFFEHGGHHHHHHHHHHHGHHGGGGGHHHHHHFHHHHGHHHHGHGGGGGHHHHHGGHHHGGGGGGHHHGGGGHHGGGGHHHHHHGGGGGGHGHHGGGGGGGHGGGGGCGHHHHGHHGHHHHHHHEDHHGHGGGGGD;BEGGGFFGGGGC:CFGGGGGGGGGFGGGFFFGFFFFF;FFF;BFFFFFFFFFFFB:FFFFD=CAEEEF>-
+@M01368:8:000000000-A3GHV:1:1111:8665:25542/1
+TCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTGTCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCG
++
+AA3AAFFFFFFFGGGFGFFGGGGHGH4AGGGFHHCGEE2FGHHHHHHHHHHGFHGF53FHEGGFAF5CFHHGGFGHFHHGGHHHCHHHHHHHFHHGH?EEEG1FFFEHHFHFGGHHGG?F4FBGHGHCHEF0//-9--;0CFGG?@BGDGFFFFEFBBBDA?FFBFFFF=B;-9.AA9EFFFF/;9BD.//;9/9/B:/:BFBFFBFFF/B:BFF//;/B/FFFBFF.A-BFFFBA/F//BFFFBF/;/A-
+@M01368:8:000000000-A3GHV:1:1111:9655:13916/1
+GGCCCATAACACTTGGGGGTAGCTAAAGTGAACTGTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGCGGTGTCCACGCAATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGA
++
+1>>1AAFFFFFBGGFE1EEEEGGHGHHH2FGHHHFGFGHGCFGGGEFHGGEGGHHHHGHEFBFEGHHHGHHBEHHHHGHGFHHHGGGGHHEGGGGHHHGFHGHHHH1FHHG?G/AGF1GBFGEFFHF2FDD0FG<GDHBFDGFFCGH//B//?0GFFGFGGHHHFHFB.=1FDFB?FGH.C/.-:::CH0;CAB@-.;0CGFFFGG--9.A@GB>--99@=---AAABA-BF/B?A@F-9BBFF//BB/9/
+@M01368:8:000000000-A3GHV:1:1112:10272:7828/1
+GTATCCGACATCTGGTTCCTACTTCAGGGTCATAAAACCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTT
++
+AAABABBBBBBFGGGGGGGGGGHGHHGHGHHHHHHHHHGHHHGGHDGHHHGGGGHHHHHHHHHHHHHHHFHGHHHHGGHGGHHHFHHHHHCGHFFHHHHHHHHHHHHHGHGEFGAEEEEHHGHHGHGHHHHHHHGHHHHHHGHGHFFBC/BA?BGGGFFFFFFFFFFFFFFFC-@DDFFFFFFFEFAFFFFFFBFBFFFFFFFFFFFFFFFFBFF->@FFFFFFFFFFBFBFAD--.99;A?////:.9A.
+@M01368:8:000000000-A3GHV:1:1112:9832:16531/1
+CTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGGGCTGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCTTGAAGTAGGAACC
++
+AABABFFFFFFFF4GGGGEBGEFGHGGHGHGHHHGGHFBGFGGGGGHHEFHGEHFHFHEHHHHHGCGGGHFHHCFGHE@1EEEFFGB?EEEEHBGGGCHHGHHBEE@>EAHHFAEBDGGGCEFF?CEGFFHHHHHFHHHFHGHCGCAHHF<..C.D=0CD.GFHHHG.CAGHC:CHB0GGGFFB0:CFA.A-;9.;000CBBFFBFGA.9AA;A;EDDE.ABBFFFF9;BEFFF/BF//9/B//9:B//..
+@M01368:8:000000000-A3GHV:1:1112:9832:6701/1
+CGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGA
++
+AABBBBFFFFFFGGGFGGGGGGHHHGGHGGHHHHHHHHHHHGHHGGGGGHHHHHHHHHHHHHHHHHHGGCGDHHHHFGGHHHGGGGGFGGHGGGGHHGGGGHHHHHHGGGGGGHHGGGGDGGFGHGGFCDCHHHHGHHHHGHHFAGFGGEHFGEG.C<EGCECEFCFFHBGHE:GHHGFF0FFFB0CFGGGGAGFFF0;;FFGGGFFGFFCDD.DEFBEDD?9FFFFFFFFFFFFFFF/B./FB///;BF/
+@M01368:8:000000000-A3GHV:1:1113:13532:8618/1
+GGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGCTACAGTTCACTTTAGCTACCTCCAAGTGTTATG
++
+AA?AAFFFFFFFGGGGGFBFGGGGGGH5GHFEDHHGGGGCGFBGH?AEEHFFEEGHGHHHHGGG?0EHGHHGGGGGC?GEE/EE?GHHHGBHFHHHHHHGHHGHHHGGGCG/A@<FGGHHHHHHHFF/GFDGHHHHHHGFFFGHGGHABGHFHHHHHFHEGDGHGDDEEHHBEDDEGFGHGBFFBFFEGGGEFGFGFB000;F0F;FGGEGGEFFF;-.9//B///B9FFFFF/BFFB/:.BB//;FBFFF
+@M01368:8:000000000-A3GHV:1:1113:21679:18011/1
+GATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGAGGGTGTGCACGCGATAGCATTGCGAGACGCTTGAGCCGGAGCACCCTATGTCGCAGTATATGTCTTTGATTCCTGCCTCTTCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACTGTCTCTTATACACATATCCACGCCCACGAGACTAAGGCGAAGTTCATT
++
+AA>1>11F1D1DDFFFFGGG1FH3GHGHGHGHFHEC?EC0B1FBGFB1GHHH21AF2HH2FEGEHAE10AAE/>/FFHE?/E/?E1@EFFH?E@/EGGG//B11B//<@@C0F/<0<FFDGGCC?FF221<BDD11@<11@DDCGEF1<111F1<F1FBGHGHCF-CHHFA./</0CGHF<0CC/;C-:-;;09;FFBFBBFFBC0FFFGGFC0009C00090/-:--9--;-;AFFE;/99-9--/;///
+@M01368:8:000000000-A3GHV:1:1113:25528:14016/1
+CCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGG
++
+>AAAAFFFBFFFGGGGGGGGGGHHFHGHHHHGHHHHHHHHHHHGGGGHHHHFHHHHFHGHHHHGAFFEFHEGHHHHHHHHGHEHHGGFGGGHHHHHHFHHHHHGGHHHHGGGGGHFHHFF?HHGGFECEFFGHFFGFHGECDGHGBGFHGDF@@?CGFHCEGGGFD.CCC?EGHBHHHFHHFBCFFGEB/CEGGGGDAA.90C9CEBFGGBBF/9.9FBFFFBBFF//99FFFFEABF//99FFEFFFBFF
+@M01368:8:000000000-A3GHV:1:1113:5741:16959/1
+TAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGA
++
+ABBBBFFFFFFFGGGFGGGGGGHHHGHHGGHBGHGAGFFCAFGHGFFGHHGFHHHHHGGGGGHGHHHHHHHHE3BFFHHHGG0EDF@GHFFGGGHGGGGGGGGGGGGGHHGGEEFHGFHHDDG@DGGGHHGDGGGGGHGG?CF?HHGHHHGHGHHHFFHGGGHHHHGGCD.;0<C;CGGGGEFF/.;0;FFFBF/0;0CFGFFB..9B/;0CBFFBBFFFFBAC?DED9;B9AD;.FFFB/B/;FBA/B//
+@M01368:8:000000000-A3GHV:1:1114:10130:11959/1
+CGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTCTGATCTGTCTCTTATACACATCTCCGAGCCCACGAGACTAAGGCGAATCTCGTATGCCGTCTTCTGCTTGCAACAAACACACATCCAGA
++
+>A33>FFFFFF@FFFGGGGFGGD4EGGGGGHHGFFGHFGGHHHFEFHECFHHHEHGAGBCCGCCEGGHGHEGFBFHFHHHHGGGHFHGHEGGGFEGEGG??@DBGHGGC-@FFGHFHFHB-??DA-DD@9:BEBG@B?E?A.ABBFBFA??F.FF/BFFB/B9B/9;BF9FF9FFFFFFFFFFFFFF?BB?;9EE;-;DDB9//;B-B@;ABFFEFFFF/-.9A.;//9/BF./B/..9.9:...//////
+@M01368:8:000000000-A3GHV:1:1114:14540:5315/1
+CTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGGGGGCTATTTAGGTTTTT
++
+AABCCFFFFFFFGGGGGGGGGGHHHHHHHFHHHHGHHGHHGGGHGGHHHHHHHGHHHHHHGGGGGHHFHHHFGHHGGFHHHHHGGGGGHHHGHGGHHHGGGGGGHGHGGGGHHGGGGHHHHHEGDDFGFFFHHGGGGGCDAFCFGFDHHHHGGHGHHHHHHBCGEHHHHGGHG.ACGEHGG0CBFFF:A;BB0;09CGF00CFFFE0AA?//CFFFFFFFFFFFFFFFBEF;A.-=A--:BBFB90;;FE.
+@M01368:8:000000000-A3GHV:1:1114:15066:16302/1
+TAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGTGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTTCAATATTACAGGCGAACATACTTACTAACGGTTGTTAATTAATTATTGCTTGTAGGACA
++
+BBBBAFFBDFBFBGGGGGFGGGBGFFFHGFHHGFFFHGHHHGHHHHFFHHHGHGC?AEFFHEFBFFFGHHHHH1FDGFFHGHGHFEGCGC-<<AHHHGGGGGGGFHH0GHFCCCADGGG?.9/A-???DGGFFF.9F9/EE-;;BBBFFBFFFFFFFFFEFFFFBFFBBFFFFF/BFFBFFFFF-DBFFF;/BFF//BB//9/BEA---9:BFFFFFF/F/.;.:@9.BBFF/;BFF/;/////9/////.
+@M01368:8:000000000-A3GHV:1:1114:16639:15258/1
+CCTAAATAGCCCACACGTTCCCCTTAAATAAGACATCACGATGGATCACAGGTCTATCACCCTATTAACCACTCACGGGAGCTCTCCATGCATTTGGTATTTTCGTCTGGGGGGTGCGCACGCGATAGCATTGCGAGACGCTGGAGCCGGAGCACCCTATGTCGCAGTATCTGTCTTTGATTCCTGCCTCATCCTATTATTTATCGCACCTACGTCCAATATTACAGGCGAACATACTTACTAAATTGTGT
++
+11>>ABFFFFFFGGCGC1BBF1GHHHBHHHHGFHGH1A100AA/GGEHGFBAA1FFD2FHHHHECG2F1BB/E0FC/A>EE/FGGFGEF1EGBBEHHCGGGHBGEHFHE0B?E--;C?CCGGG@A@GBFBBBB09?@??A-AB--ABE@=-=-9AE9A;FFFFFE=9-//;//;9FF/////;;///9B///;/B////9FFBB;--A@-;/9;9-:-/;;FFFE9BF?@;-9-99/B9F/://///99/;
+@M01368:8:000000000-A3GHV:1:1114:2404:13066/1
+TCCTACAAGCATTAATTAATTAACACACTTTAGTAAGTATGTTCGCCTGTAATATTGAACGTAGGTGCGATAAATAATAGGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCTGTCTATTATACACATC
++
+CCCCCFFFFCFFGGGGGGGGGGHHHHHGHHHHHHHHHFFHHHHHGGGGHHHHHHHHFHHHHHHFGGHHGGHGGHHHHHHGHHFHHHHGGGGGGHHHHHHGHHHHHHHHHHGGGGGGGHH?FGHHHGGGGGGHHGGFGGHHGGGGHHHHHFGGGGFGHGHHGGGGGGGHGGGEGGHHGHHHHHHHHHGFBFFDA0FGGGFFGG0:EFGGGGGGGG;AEBF0B0BFFBFFFFFFFFFFFFFFFFFFFFFEFF0
+@M01368:8:000000000-A3GHV:1:1114:9184:6959/1
+GGATGAGGCAGGAATCAAAGACAGATACTGCGACATAGGGTGCTCCGGCTCCAGCGTCTCGCAATGCTATCGCGTGCACACCCCCCAGACGAAAATACCAAATGCATGGAGAGCTCCCGTGAGTGGTTAATAGGGTGATAGACCTGTGATCCATCGTGATGTCTTATTTAAGGGGAACGTGTGGGCTATTTAGGTTTTATGACCCTGAAGTAGGAACCAGATGTCGGATACAGTTCACTTTCTGTCTCTTA
++
+AABBBFFFCCCBFGGGGGGGGGHHHHHHHHGGGGGGHHHG3FFHHHFGFGGGHHHGGGEHHGGGGHHHHHHGGGGGGHGHGGGGGGGDEGGGGEGGFHHHHHHHHHHHHGGGFGEHHGGFDGGGDFFGFHHHHGFCFHHHHHEFHFHGGFFGHHGGGHHHHDGHHHFHHHFFFFGFGGG.EFGGGGFGEBFGGGFGFGGGGFFBFGGBBFFFFFB/FEFF?///;A::AABBFFFBFFFFFFFFFBFFFF/
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/geographic_location_1.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,279 @@
+not applicable
+not collected
+not provided
+restricted access
+Afghanistan
+Albania
+Algeria
+American Samoa
+Andorra
+Angola
+Anguilla
+Antarctica
+Antigua and Barbuda
+Arctic Ocean
+Argentina
+Armenia
+Aruba
+Ashmore and Cartier Islands
+Atlantic Ocean
+Australia
+Austria
+Azerbaijan
+Bahamas
+Bahrain
+Baker Island
+Baltic Sea
+Bangladesh
+Barbados
+Bassas da India
+Belarus
+Belgium
+Belize
+Benin
+Bermuda
+Bhutan
+Bolivia
+Borneo
+Bosnia and Herzegovina
+Botswana
+Bouvet Island
+Brazil
+British Virgin Islands
+Brunei
+Bulgaria
+Burkina Faso
+Burundi
+Cambodia
+Cameroon
+Canada
+Cape Verde
+Cayman Islands
+Central African Republic
+Chad
+Chile
+China
+Christmas Island
+Clipperton Island
+Cocos Islands
+Colombia
+Comoros
+Cook Islands
+Coral Sea Islands
+Costa Rica
+Cote d'Ivoire
+Croatia
+Cuba
+Curacao
+Cyprus
+Czech Republic
+Democratic Republic of the Congo
+Denmark
+Djibouti
+Dominica
+Dominican Republic
+East Timor
+Ecuador
+Egypt
+El Salvador
+Equatorial Guinea
+Eritrea
+Estonia
+Ethiopia
+Europa Island
+Falkland Islands (Islas Malvinas)
+Faroe Islands
+Fiji
+Finland
+France
+French Guiana
+French Polynesia
+French Southern and Antarctic Lands
+Gabon
+Gambia
+Gaza Strip
+Georgia
+Germany
+Ghana
+Gibraltar
+Glorioso Islands
+Greece
+Greenland
+Grenada
+Guadeloupe
+Guam
+Guatemala
+Guernsey
+Guinea
+Guinea-Bissau
+Guyana
+Haiti
+Heard Island and McDonald Islands
+Honduras
+Hong Kong
+Howland Island
+Hungary
+Iceland
+India
+Indian Ocean
+Indonesia
+Iran
+Iraq
+Ireland
+Isle of Man
+Israel
+Italy
+Jamaica
+Jan Mayen
+Japan
+Jarvis Island
+Jersey
+Johnston Atoll
+Jordan
+Juan de Nova Island
+Kazakhstan
+Kenya
+Kerguelen Archipelago
+Kingman Reef
+Kiribati
+Kosovo
+Kuwait
+Kyrgyzstan
+Laos
+Latvia
+Lebanon
+Lesotho
+Liberia
+Libya
+Liechtenstein
+Lithuania
+Luxembourg
+Macau
+Macedonia
+Madagascar
+Malawi
+Malaysia
+Maldives
+Mali
+Malta
+Marshall Islands
+Martinique
+Mauritania
+Mauritius
+Mayotte
+Mediterranean Sea
+Mexico
+Micronesia
+Midway Islands
+Moldova
+Monaco
+Mongolia
+Montenegro
+Montserrat
+Morocco
+Mozambique
+Myanmar
+Namibia
+Nauru
+Navassa Island
+Nepal
+Netherlands
+New Caledonia
+New Zealand
+Nicaragua
+Niger
+Nigeria
+Niue
+Norfolk Island
+North Korea
+North Sea
+Northern Mariana Islands
+Norway
+Oman
+Pacific Ocean
+Pakistan
+Palau
+Palmyra Atoll
+Panama
+Papua New Guinea
+Paracel Islands
+Paraguay
+Peru
+Philippines
+Pitcairn Islands
+Poland
+Portugal
+Puerto Rico
+Qatar
+Republic of the Congo
+Reunion
+Romania
+Ross Sea
+Russia
+Rwanda
+Saint Helena
+Saint Kitts and Nevis
+Saint Lucia
+Saint Pierre and Miquelon
+Saint Vincent and the Grenadines
+Samoa
+San Marino
+Sao Tome and Principe
+Saudi Arabia
+Senegal
+Serbia
+Seychelles
+Sierra Leone
+Singapore
+Sint Maarten
+Slovakia
+Slovenia
+Solomon Islands
+Somalia
+South Africa
+South Georgia and the South Sandwich Islands
+South Korea
+Southern Ocean
+Spain
+Spratly Islands
+Sri Lanka
+Sudan
+Suriname
+Svalbard
+Swaziland
+Sweden
+Switzerland
+Syria
+Taiwan
+Tajikistan
+Tanzania
+Tasman Sea
+Thailand
+Togo
+Tokelau
+Tonga
+Trinidad and Tobago
+Tromelin Island
+Tunisia
+Turkey
+Turkmenistan
+Turks and Caicos Islands
+Tuvalu
+USA
+Uganda
+Ukraine
+United Arab Emirates
+United Kingdom
+Uruguay
+Uzbekistan
+Vanuatu
+Venezuela
+Viet Nam
+Virgin Islands
+Wake Island
+Wallis and Futuna
+West Bank
+Western Sahara
+Yemen
+Zambia
+Zimbabwe
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/host_health_state_1.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,6 @@
+not applicable
+diseased
+healthy
+not provided
+not collected
+restricted access
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/host_sex_1.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,9 @@
+other
+not applicable
+not provided
+neuter
+not collected
+female
+restricted access
+male
+hermaphrodite
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/instrument_model.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,58 @@
+minION
+GridION
+PromethION
+454 GS
+454 GS 20
+454 GS FLX
+454 GS FLX+
+454 GS FLX Titanium
+454 GS Junior
+Illumina Genome Analyzer
+Illumina Genome Analyzer II
+Illumina Genome Analyzer IIx
+Illumina HiSeq 1000
+Illumina HiSeq 1500
+Illumina HiSeq 2000
+Illumina HiSeq 2500
+Illumina HiSeq 3000
+Illumina HiSeq 4000
+Illumina iSeq 100
+Illumina HiScanSQ
+Illumina NextSeq 500
+Illumina NextSeq 550
+Illumina NovaSeq 6000
+Illumina HiSeq X Five
+Illumina HiSeq X Ten
+Illumina MiSeq
+Illumina MiniSeq
+AB SOLiD System
+AB SOLiD System 2.0
+AB SOLiD System 3.0
+AB SOLiD 3 Plus System
+AB SOLiD 4 System
+AB SOLiD 4hq System
+AB SOLiD PI System
+AB 5500 Genetic Analyzer
+AB 5500xl Genetic Analyzer
+AB 5500xl-W Genetic Analysis System
+Ion Torrent PGM
+Ion Torrent Proton
+Ion Torrent S5
+Ion Torrent S5 XL
+Complete Genomics
+PacBio RS
+PacBio RS II
+Sequel
+Sequel II
+AB 3730xL Genetic Analyzer
+AB 3730 Genetic Analyzer
+AB 3500xL Genetic Analyzer
+AB 3500 Genetic Analyzer
+AB 3130xL Genetic Analyzer
+AB 3130 Genetic Analyzer
+AB 310 Genetic Analyzer
+BGISEQ-500
+DNBSEQ-T7
+DNBSEQ-G400
+DNBSEQ-G50
+DNBSEQ-G400 FAST
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/library_layout.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,2 @@
+SINGLE
+PAIRED
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/library_selection.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,27 @@
+RANDOM
+PCR
+RANDOM PCR
+RT-PCR
+HMPR
+MF
+repeat fractionation
+size fractionation
+MSLL
+cDNA
+ChIP
+MNase
+DNase
+Hybrid Selection
+Reduced Representation
+Restriction Digest
+5-methylcytidine antibody
+MBD2 protein methyl-CpG binding domain
+CAGE
+RACE
+MDA
+padlock probes capture method
+Oligo-dT
+Inverse rRNA selection
+ChIP-Seq
+other
+unspecified
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/library_source.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,7 @@
+GENOMIC
+TRANSCRIPTOMIC
+METAGENOMIC
+METATRANSCRIPTOMIC
+SYNTHETIC
+VIRAL RNA
+OTHER
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/library_strategy.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,38 @@
+WGS
+WGA
+WXS
+RNA-Seq
+ssRNA-seq
+miRNA-Seq
+ncRNA-Seq
+FL-cDNA
+EST
+Hi-C
+ATAC-seq
+WCS
+RAD-Seq
+CLONE
+POOLCLONE
+AMPLICON
+CLONEEND
+FINISHING
+ChIP-Seq
+MNase-Seq
+DNase-Hypersensitivity
+Bisulfite-Seq
+CTS
+MRE-Seq
+MeDIP-Seq
+MBD-Seq
+Tn-Seq
+VALIDATION
+FAIRE-seq
+SELEX
+RIP-Seq
+ChIA-PET
+Synthetic-Long-Read
+Targeted-Capture
+Tethered Chromatin Conformation Capture
+ChM-Seq
+GBS
+OTHER
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool-data/study_type.loc.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,14 @@
+Whole Genome Sequencing
+Metagenomics
+Transcriptome Analysis
+Resequencing
+Epigenetics
+Synthetic Genomics
+Forensic or Paleo-genomics
+Gene Regulation Study
+Cancer Genomics
+Population Genomics
+RNASeq
+Exome Sequencing
+Pooled Clone Sequencing
+Transcriptome Sequencing
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool_data_table_conf.xml.sample	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,13 @@
+<?xml version="1.0"?>
+    <tables>
+        <table name="study_type" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/study_type.loc" /></table>
+        <table name="library_layout" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/library_layout.loc" /></table>
+        <table name="library_selection" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/library_selection.loc" /></table>
+        <table name="instrument_model" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/instrument_model.loc" /></table>
+        <table name="library_source" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/library_source.loc" /></table>
+        <table name="library_strategy" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/library_strategy.loc" /></table>
+        <table name="geographic_location_1" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/geographic_location_1.loc" /></table>
+        <table name="host_sex_1" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/host_sex_1.loc" /></table>
+        <table name="host_health_state_1" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="tool-data/host_health_state_1.loc" /></table>
+    </tables>
+
--- /dev/null	Thu Jan 01 00:00:00 1970 +0000
+++ b/tool_data_table_conf.xml.test	Sat Nov 28 09:45:44 2020 +0000
@@ -0,0 +1,12 @@
+<!-- Paths are relative to the value of `tool_data_path` in galaxy.ini -->
+<tables>
+    <table name="study_type" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/study_type.loc.sample" /></table>
+    <table name="library_layout" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/library_layout.loc.sample" /></table>
+    <table name="library_selection" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/library_selection.loc.sample" /></table>
+    <table name="instrument_model" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/instrument_model.loc.sample" /></table>
+    <table name="library_source" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/library_source.loc.sample" /></table>
+    <table name="library_strategy" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/library_strategy.loc.sample" /></table>
+    <table name="geographic_location_1" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/geographic_location_1.loc.sample" /></table>
+    <table name="host_sex_1" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/host_sex_1.loc.sample" /></table>
+    <table name="host_health_state_1" comment_char="#" allow_duplicate_entries="False"><columns>value</columns><file path="${__HERE__}/tool-data/host_health_state_1.loc.sample" /></table>
+</tables>