Mercurial > repos > iuc > gatk2
diff readme.rst @ 0:340633249b3d draft
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author | bgruening |
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date | Mon, 02 Dec 2013 06:18:36 -0500 |
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children | 8bcc13094767 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/readme.rst Mon Dec 02 06:18:36 2013 -0500 @@ -0,0 +1,84 @@ +Galaxy wrapper for GATK2 +======================== + +This wrapper is copyright 2013 by Björn Grüning, Jim Johnson & the Galaxy Team. + +The Genome Analysis Toolkit or GATK is a software package developed at the +Broad Institute to analyse next-generation resequencing data. The toolkit offers +a wide variety of tools, with a primary focus on variant discovery and +genotyping as well as strong emphasis on data quality assurance. Its robust +architecture, powerful processing engine and high-performance computing features +make it capable of taking on projects of any size. + +http://www.broadinstitute.org/gatk +http://www.broadinstitute.org/gatk/about/citing-gatk + + +GATK is Free for academics, and fee for commercial use. Please study the GATK licensing website: +http://www.broadinstitute.org/gatk/about/#licensing + + +Installation +============ + +The recommended installation is by means of the toolshed_. + +.. _toolshed: http://toolshed.g2.bx.psu.edu/view/bjoern-gruening/augustus + +Galaxy should be able to automatically install samtools dependencies automatically +for you. GATK2, and its new licence model, does not allow us to distribute the GATK binaries. +As a consequence you need to install GATK2 by your own, please see the GATK website for more informations: + +http://www.broadinstitute.org/gatk/download + +Once you have installed GATK2 you need to edit the env.sh file that is installed with these wrappers. +You will find this env.sh file under: + +<tool_dependency_dir>/gatk2/<version>/iuc/<hash_string>/env.sh + +You should edit the GATK2_PATH environment variable to point to the folder you have installed GATK2 +and if you want to deactivate the 'call home feature' from GATK you can set + +GATK2_SITE_OPTIONS='-et "NO_ET" -K "/data/gatk2_key_file"' + +GATK2_SITE_OPTIONS can be used to insert specific options into every GATK2 wrapper +during runtime, without changing the actuall wrapper. + +Read more about the "Phone Home" problem under: +http://www.broadinstitute.org/gatk/guide/article?id=1250 + + +Finally, you should fill in additional information about your genomes and +annotations in the gatk2_picard_index.loc and gatk2_annotations.txt. +You can find them under ./tool-data/. + + + +History +======= + +v0.1 - Initial public release + + +Licence (MIT) +============= + +Permission is hereby granted, free of charge, to any person obtaining a copy +of this software and associated documentation files (the "Software"), to deal +in the Software without restriction, including without limitation the rights +to use, copy, modify, merge, publish, distribute, sublicense, and/or sell +copies of the Software, and to permit persons to whom the Software is +furnished to do so, subject to the following conditions: + +The above copyright notice and this permission notice shall be included in +all copies or substantial portions of the Software. + +THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR +IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, +FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE +AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER +LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, +OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN +THE SOFTWARE. + +