Mercurial > repos > iuc > gemini_recessive_and_dominant
diff gemini_autosomal_recessive.xml @ 0:69ec574f6f41 draft
planemo upload for repository https://github.com/bgruening/galaxytools/tree/master/tools/gemini commit 4bbfca6f0e9cae9a8f263aad4eab7304c96358c4
| author | iuc |
|---|---|
| date | Thu, 18 Feb 2016 08:53:48 -0500 |
| parents | |
| children | 4086bb81f52a |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/gemini_autosomal_recessive.xml Thu Feb 18 08:53:48 2016 -0500 @@ -0,0 +1,100 @@ +<tool id="gemini_recessive_and_dominant" name="GEMINI autosomal recessive/dominant" version="@VERSION@.0"> + <description>Find variants meeting an autosomal recessive/dominant model</description> + <macros> + <import>gemini_macros.xml</import> + </macros> + <expand macro="requirements" /> + <expand macro="stdio" /> + <expand macro="version_command" /> + <command> +<![CDATA[ + gemini + + #if str($rec_or_dom) == 'recessive': + ## start autosomal_recessive + autosomal_recessive + #else: + ## start autosomal_dominant + autosomal_dominant + #end if + + #if str($report.report_selector) != 'all': + --columns "${report.columns}" + #end if + + @CMDLN_SQL_FILTER_FILTER_OPTION@ + + -d $d + #if int($min_kindreds) > 0: + --min-kindreds $min_kindreds + #end if + + #if str($families).strip(): + --families "$families" + #end if + + $lenient + $allow_unaffected + + #if int($min_gq) > 0: + --min-gq $min_gq + #end if + + #if int($gt_pl_max) > -1: + --gt-pl-max $gt_pl_max + #end if + + "${ infile }" + > "${ outfile }" +]]> + </command> + <inputs> + + <param name="rec_or_dom" type="select" label="Autosomal ..." help=""> + <option value="recessive">recessive</option> + <option value="dominant">dominant</option> + </param> + + <expand macro="infile" /> + <expand macro="column_filter" /> + <expand macro="filter" /> + <expand macro="min_sequence_depth" /> + <expand macro="family" /> + <expand macro="lenient" /> + <expand macro="unaffected" /> + <expand macro="min_kindreds" /> + <expand macro="min_gq" /> + <expand macro="gt_pl_max" /> + + </inputs> + <outputs> + <data name="outfile" format="tabular" /> + </outputs> + <tests> + <test> + <param name="infile" value="gemini_autosomal_input.db" ftype="gemini.sqlite" /> + <param name="rec_or_dom" value="dominant" /> + <param name="report_selector" value="column_filter" /> + <param name="columns" value="gene,chrom,impact" /> + <param name="lenient" value="true" /> + <output name="outfile" file="gemini_autosomal_dominant_result.tabular" /> + </test> + <test> + <param name="infile" value="gemini_autosomal_input.db" ftype="gemini.sqlite" /> + <param name="rec_or_dom" value="recessive" /> + <param name="report_selector" value="column_filter" /> + <param name="columns" value="gene,chrom,impact" /> + <param name="lenient" value="true" /> + <output name="outfile" file="gemini_autosomal_recessive.tabular" /> + </test> + </tests> + <help> +**What it does** + +Assuming you have defined the familial relationships between samples when loading your VCF into GEMINI, one can leverage a +built-in tool for identifying variants that meet an autosomal recessive or dominant inheritance pattern. +The reported variants will be restricted to those variants having the potential to impact the function of affecting protein coding transcripts. + + </help> + <expand macro="citations"/> +</tool>
