annotate hmmemit.xml @ 1:b5066aa77fea draft

planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit f7d83adb11624763b9b113f938a1d5f311c8f9fa-dirty
author iuc
date Sat, 19 Sep 2015 17:05:45 -0400
parents 62479bdcc059
children
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62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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1 <?xml version="1.0"?>
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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2 <tool id="hmmer_hmmemit" name="hmmemit" version="@WRAPPER_VERSION@.0">
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3 <description>sample sequence(s) from a profile HMM</description>
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4 <macros>
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5 <import>macros.xml</import>
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6 </macros>
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7 <expand macro="requirements"/>
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8 <expand macro="stdio"/>
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9 <command><![CDATA[
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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10 hmmemit
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11
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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12 #if $oformat.oformat_select == "fasta":
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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13 -N $oformat.N_fa
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14 #elif $oformat.oformat_select == "aln":
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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15 -N $oformat.N_aln
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16 -a
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17 #elif $oformat.oformat_select == "mrcs":
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18 -c
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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19 #elif $oformat.oformat_select == "mrcsf":
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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20 --minl $oformat.minl
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21 --minu $oformat.minu
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22 -C
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23 #else:
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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24 -N $oformat.N_smp
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25 -p
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26 #if $oformat.L:
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27 -L $oformat.L
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28 #end if
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29 $oformat.emission_profiles
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30 #end if
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31
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32
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33 @SEED@
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34
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35 $hmmfile
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36 > $output
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37 ]]></command>
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38 <inputs>
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39 <expand macro="input_hmm" />
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40
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41 <conditional name="oformat">
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42 <param name="oformat_select" type="select" label="Output Format">
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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43 <option value="fasta" selected="true">Fasta</option>
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44 <option value="aln">Alignment</option>
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45 <option value="mrcs">Majority-Rule Concensus Sequence</option>
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46 <option value="mrcsf">Fancier Concensus Sequence</option>
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47 <option value="sample">Sample sequences from profile, not core model</option>
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48 </param>
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49 <when value="fasta">
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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50 <param name="N_fa" type="integer" value="1" min="1" help="(-N)"
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51 label="Number of sequences to generate"/>
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52 </when>
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53 <when value="aln">
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54 <param name="N_aln" type="integer" value="1" min="1" help="(-N)"
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55 label="Number of sequences to generate"/>
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56 </when>
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57 <when value="mrcs">
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58 </when>
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59 <when value="mrcsf">
62479bdcc059 planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 4164b44c651bcbdac6637eccce61b2a802c9b569
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60 <param name="minl" type="float" value="0.7" help="(--minl)"
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61 label="show consensus as 'any' (X/N) unless >= this fraction"/>
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62 <param name="minu" type="float" value="0.2" help="(--minu)"
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63 label="show consensus as upper case if >= this fraction"/>
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64 </when>
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65 <when value="sample">
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66 <param name="N_smp" type="integer" value="1" min="1" help="(-N)"
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67 label="Number of sequences to generate"/>
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68 <param name="L" type="integer" optional="True" help="(-L)"
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69 label="Expected length of profile"/>
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70
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71 <param name="emission_profiles" type="select" label="Emission profile options">
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72 <option value="--local" selected="true">configure profile in multihit local mode</option>
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73 <option value="--unilocal">configure profile in unilocal mode</option>
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74 <option value="--glocal">configure profile in multihit glocal mode</option>
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75 <option value="--uniglocal">configure profile in unihit glocal mode</option>
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76 </param>
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77 </when>
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78 </conditional>
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79
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80
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81 <expand macro="seed"/>
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82 </inputs>
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83 <outputs>
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84 <data format="fasta" name="output" label="Sequences generated from $hmmfile.name">
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85 <change_format>
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86 <when input="oformat_select" value="aln" format="stockholm"/>
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87 <!-- the rest are fasta -->
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88 </change_format>
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89 </data>
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90 </outputs>
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91 <tests>
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92 <test>
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93 <param name="hmmfile" value="globins4.hmm"/>
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94 <param name="oformat_select" value="aln"/>
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95 <param name="N_aln" value="10"/>
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96 <expand macro="seed_test" />
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97 <output name="output" file="globins4-emit.sto" lines_diff="4"/>
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98 </test>
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99 <test>
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100 <param name="hmmfile" value="globins4.hmm"/>
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101 <param name="oformat_select" value="fasta"/>
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102 <param name="N_aln" value="10"/>
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103 <expand macro="seed_test" />
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104 <output name="output" file="globins4-emit-1.sto" lines_diff="4"/>
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105 </test>
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106 </tests>
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107 <help><![CDATA[
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108 @HELP_PRE@
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109
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110 The hmmemit program samples (emits) sequences from the profile HMM(s) in
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111 hmmfile, and writes them to output. Sampling sequences may be useful for a
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112 variety of purposes, including creating synthetic true positives for benchmarks
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113 or tests.
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114
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115 The default is to sample one unaligned sequence from the core probability
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116 model, which means that each sequence consists of one full-length domain.
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117 Alternatively, with the -c option, you can emit a simple majority-rule
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118 consensus sequence; or with the -a option, you can emit an alignment (in which
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119 case, you probably also want to set -N to something other than its default of 1
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120 sequence per model).
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121
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122 As another option, with the -p option you can sample a sequence from a fully
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123 configured HMMER search profile. This means sampling a ‘homologous sequence’ by
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124 HMMER’s definition, including nonhomologous flanking sequences, local
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125 alignments, and multiple domains per sequence, depending on the length model
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126 and alignment mode chosen for the profile.
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127
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128 The hmmfile may contain a library of HMMs, in which case each HMM will be used
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129 in turn.
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130
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131 @HELP_PRE_OTH@
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132
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133 Output Formats
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134 --------------
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135
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136 Several output formats are available, each with different options.
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137
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138 **Fasta**
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139
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140 Fasta option is the easiest to understand, given an input model, it will produce N sequences in fasta format from that model.
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141
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142 **Alignment**
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143
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144 Produces a stockholm alignment, of what the Fasta output would have produced.
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145
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146 **Majority-Rule Concensus Sequence**
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147
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148 Emit a plurality-rule consensus sequence, instead of sampling a sequence from
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149 the profile HMM’s probability distribution. The consensus sequence is formed by
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150 selecting the maximum probability residue at each match state.
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151
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152 **Fancier Concensus Sequence**
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153
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154 Emit a fancier plurality-rule consensus sequence than the -c option. If the
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155 maximum probability residue has p < minl show it as a lower case ’any’ residue
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156 (n or x); if p >= minl and < minu show it as a lower case residue; and if p >=
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157 minu show it as an upper case residue. The default settings of minu and minl
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158 are both 0.0, which means -C gives the same output as -c unless you also set
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159 minu and minl to what you want.
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160
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161 **Sample**
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162
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163 Sample unaligned sequences from the implicit search profile, not from the core
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164 model. The core model consists only of the homologous states (between the begin
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165 and end states of a HMMER Plan7 model). The profile includes the nonhomologous
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166 N, C, and J states, local/glocal and uni/multihit algorithm configuration, and
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167 the target length model. Therefore sequences sampled from a profile may in-
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168 clude nonhomologous as well as homologous sequences, and may contain more than
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169 one homologous sequence segment. By default, the profile is in multihit local
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170 mode, and the target sequence length is configured for L=400.
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171
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172 @ATTRIBUTION@
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173 ]]></help>
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174 <expand macro="citation"/>
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175 </tool>