# HG changeset patch # User iuc # Date 1626876608 0 # Node ID be072920a53ebde9fb68f2608da4feffa9353337 # Parent d92dd2f040cdb44aa17c725ef2a483cbb9f112b8 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hmmer3 commit 0bccf5220ed6549db7e053f85bbe917326b0a0be" diff -r d92dd2f040cd -r be072920a53e hmmscan.xml --- a/hmmscan.xml Thu Jan 14 15:43:54 2021 +0000 +++ b/hmmscan.xml Wed Jul 21 14:10:08 2021 +0000 @@ -1,5 +1,5 @@ - + search protein sequence(s) against a protein profile database macros.xml @@ -26,7 +26,7 @@ - + @@ -41,7 +41,7 @@ - + diff -r d92dd2f040cd -r be072920a53e macros.xml --- a/macros.xml Thu Jan 14 15:43:54 2021 +0000 +++ b/macros.xml Wed Jul 21 14:10:08 2021 +0000 @@ -6,7 +6,7 @@ - 3.3 + 3.3.2 diff -r d92dd2f040cd -r be072920a53e test-data/MADE1.hmm --- a/test-data/MADE1.hmm Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/MADE1.hmm Wed Jul 21 14:10:08 2021 +0000 @@ -1,4 +1,4 @@ -HMMER3/f [3.3 | Nov 2019] +HMMER3/f [3.3.2 | Nov 2020] NAME MADE1 ACC DF0000629.2 DESC MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon @@ -10,7 +10,7 @@ CONS yes CS no MAP yes -DATE Thu May 14 18:28:16 2020 +DATE Fri Jul 16 10:31:17 2021 NSEQ 1997 EFFN 4.772646 CKSUM 3015610723 diff -r d92dd2f040cd -r be072920a53e test-data/MADE1.nhmmscan_out --- a/test-data/MADE1.nhmmscan_out Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/MADE1.nhmmscan_out Wed Jul 21 14:10:08 2021 +0000 @@ -1,17 +1,17 @@ # nhmmscan :: search DNA sequence(s) against a DNA profile database -# HMMER 3.3 (Nov 2019); http://hmmer.org/ -# Copyright (C) 2019 Howard Hughes Medical Institute. +# HMMER 3.3.2 (Nov 2020); http://hmmer.org/ +# Copyright (C) 2020 Howard Hughes Medical Institute. # Freely distributed under the BSD open source license. # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -# query sequence file: /tmp/tmpqydies2m/files/f/a/5/dataset_fa559c91-0436-48cb-a47d-20062d4af284.dat +# query sequence file: /tmp/tmp2vk0_a8v/files/7/d/6/dataset_7d62e9c6-1db3-4a28-9770-d56c56ccfb17.dat # target HMM database: localref.hmm -# per-seq hits tabular output: /tmp/tmpqydies2m/files/4/7/2/dataset_4723128d-8711-4edb-8afe-a68476a6c127.dat -# hits output in Dfam format: /tmp/tmpqydies2m/files/1/a/e/dataset_1aeea50b-1263-4750-8237-4fc3f10c0999.dat +# per-seq hits tabular output: /tmp/tmp2vk0_a8v/files/7/0/4/dataset_70487df9-4948-42c0-a250-638bcc64487a.dat +# hits output in Dfam format: /tmp/tmp2vk0_a8v/files/8/0/f/dataset_80fdcb47-0041-4a2c-bc0a-4820ac3c27d0.dat # max ASCII text line length: unlimited # Vit filter P threshold: <= 0.001 # Fwd filter P threshold: <= 1e-05 # random number seed set to: 4 -# number of worker threads: 1 +# number of worker threads: 0 # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: humanchr1/239220001-239550000 [L=330000] @@ -103,7 +103,7 @@ Residues passing Vit filter: 1612 (0.00244); expected (0.001) Residues passing Fwd filter: 1194 (0.00181); expected (1e-05) Total number of hits: 5 (0.000405) -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 2289.06 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2765.21 // [ok] diff -r d92dd2f040cd -r be072920a53e test-data/MADE1.nhmmscan_out.tblout --- a/test-data/MADE1.nhmmscan_out.tblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/MADE1.nhmmscan_out.tblout Wed Jul 21 14:10:08 2021 +0000 @@ -6,12 +6,12 @@ MADE1 DF0000629.2 humanchr1/239220001-239550000 - 43 80 174493 174456 174513 174456 80 - 4.9e-06 25.0 7.0 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon MADE1 DF0000629.2 humanchr1/239220001-239550000 - 41 71 304073 304103 304053 304109 80 + 2.2 6.9 7.2 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon # -# Program: hmmscan -# Version: 3.3 (Nov 2019) +# Program: nhmmscan +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SCAN -# Query file: /tmp/tmpqydies2m/files/f/a/5/dataset_fa559c91-0436-48cb-a47d-20062d4af284.dat +# Query file: /tmp/tmp2vk0_a8v/files/7/d/6/dataset_7d62e9c6-1db3-4a28-9770-d56c56ccfb17.dat # Target file: localref.hmm -# Option settings: nhmmscan --tblout /tmp/tmpqydies2m/files/4/7/2/dataset_4723128d-8711-4edb-8afe-a68476a6c127.dat --dfamtblout /tmp/tmpqydies2m/files/1/a/e/dataset_1aeea50b-1263-4750-8237-4fc3f10c0999.dat --notextw -E 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --B1 110 --B2 240 --B3 1000 --cpu 1 localref.hmm /tmp/tmpqydies2m/files/f/a/5/dataset_fa559c91-0436-48cb-a47d-20062d4af284.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/20/working -# Date: Thu May 14 18:55:28 2020 +# Option settings: nhmmscan --tblout /tmp/tmp2vk0_a8v/files/7/0/4/dataset_70487df9-4948-42c0-a250-638bcc64487a.dat --dfamtblout /tmp/tmp2vk0_a8v/files/8/0/f/dataset_80fdcb47-0041-4a2c-bc0a-4820ac3c27d0.dat --notextw -E 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --B1 110 --B2 240 --B3 1000 --cpu 0 localref.hmm /tmp/tmp2vk0_a8v/files/7/d/6/dataset_7d62e9c6-1db3-4a28-9770-d56c56ccfb17.dat +# Current dir: /tmp/tmp2vk0_a8v/job_working_directory/000/6/working +# Date: Fri Jul 16 11:22:43 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/MADE1.out --- a/test-data/MADE1.out Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/MADE1.out Wed Jul 21 14:10:08 2021 +0000 @@ -1,79 +1,45 @@ # hmmscan :: search sequence(s) against a profile database -# HMMER 3.3 (Nov 2019); http://hmmer.org/ -# Copyright (C) 2019 Howard Hughes Medical Institute. +# HMMER 3.3.2 (Nov 2020); http://hmmer.org/ +# Copyright (C) 2020 Howard Hughes Medical Institute. # Freely distributed under the BSD open source license. # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -# query sequence file: /tmp/tmpqydies2m/files/5/d/3/dataset_5d34ccc7-9920-470e-9f13-678ab2ecd29d.dat +# query sequence file: /tmp/tmpgjabmh94/files/d/c/f/dataset_dcfa47ad-e0da-4c8c-a808-c5bbd7eb2eda.dat # target HMM database: localref.hmm -# per-seq hits tabular output: /tmp/tmpqydies2m/files/1/d/a/dataset_1da10e33-3e1c-48fc-abfb-7e3c263ec0df.dat -# per-dom hits tabular output: /tmp/tmpqydies2m/files/7/2/3/dataset_723f3cf1-e0de-4616-aec7-dd16680f3be3.dat -# pfam-style tabular hit output: /tmp/tmpqydies2m/files/7/3/4/dataset_734c7f25-0a22-431b-9a7a-58849fcd6009.dat +# per-seq hits tabular output: /tmp/tmpgjabmh94/files/9/8/3/dataset_9834554f-8f1e-4161-9c16-f4bd5042207c.dat +# per-dom hits tabular output: /tmp/tmpgjabmh94/files/8/e/b/dataset_8ebf81cb-d0c9-41a3-a725-c9e2f0d65d82.dat +# pfam-style tabular hit output: /tmp/tmpgjabmh94/files/1/f/0/dataset_1f08bd39-0984-447e-b71e-7bf3442d708d.dat # max ASCII text line length: unlimited # Vit filter P threshold: <= 0.001 # Fwd filter P threshold: <= 1e-05 # random number seed set to: 4 -# number of worker threads: 1 +# number of worker threads: 0 # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -Query: humanchr1/239220001-239550000 [L=330000] +Query: humanchr1/239220001-239550000 [L=59940] Scores for complete sequence (score includes all domains): --- full sequence --- --- best 1 domain --- -#dom- E-value score bias E-value score bias exp N Model Description ------- ------ ----- ------- ------ ----- ---- -- -------- ----------- - 9.3e-18 51.2 26.3 1.3e-12 34.8 0.7 8.6 4 MADE1 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon + + [No hits detected that satisfy reporting thresholds] Domain annotation for each model (and alignments): ->> MADE1 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon - # score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc - --- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ---- - 1 ! 27.4 0.6 2.4e-10 2.4e-10 1 43 [. 174456 174498 .. 174456 174520 .. 0.93 - 2 ? -8.4 5.8 1 1 12 79 .. 197274 197341 .. 197272 197342 .. 0.86 - 3 ! 34.8 0.7 1.3e-12 1.3e-12 2 80 .] 302388 302466 .. 302387 302466 .. 0.87 - 4 ? 1.4 0.4 0.033 0.033 27 74 .. 304060 304106 .. 304029 304108 .. 0.71 - Alignments for each domain: - == domain 1 score: 27.4 bits; conditional E-value: 2.4e-10 - xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF - MADE1 1 ttaggttggtgcaaaagtaattgcggtttttgccattactttt 43 - ttaggtt gtgcaaaagtaattg+ggtttttg cattactttt - humanchr1/239220001-239550000 174456 TTAGGTTAGTGCAAAAGTAATTGTGGTTTTTGTCATTACTTTT 174498 - 79**************************************997 PP - - == domain 2 score: -8.4 bits; conditional E-value: 1 - xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF - MADE1 12 caaaagtaattgcggtttttgccattacttttaatggcaaaaaccgcaattacttttgcaccaaccta 79 - caa gtaatt + tttt c att ttt t c aaa c c tta tt t ac a cta - humanchr1/239220001-239550000 197274 CAATGGTAATTTTATTTTTAACTATTTTATTTTTTAACTAAACTCACTTTTATTTATTTACATATCTA 197341 - 567789*******************999999999999*****99999999999988877777776666 PP - - == domain 3 score: 34.8 bits; conditional E-value: 1.3e-12 - xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF - MADE1 2 taggttggtgcaaaagtaattgcggtttttgccattacttttaatggcaaaaaccgcaattacttttgcaccaacctaa 80 - t ggt ggtgcaaaa aattg+ggtttttgccatt cttttaat gc a a t ctttt caccaa ctaa - humanchr1/239220001-239550000 302388 TTGGTCGGTGCAAAATCAATTGTGGTTTTTGCCATTGCTTTTAATTGCTTTTAAAAGTAATGCTTTTACACCAATCTAA 302466 - 6799*****************************************99953333333345578**************997 PP - - == domain 4 score: 1.4 bits; conditional E-value: 0.033 - xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx RF - MADE1 27 tttttgccattacttttaatggcaaaaaccgcaattacttttgcacca 74 - tttt g c ta tt a tgg aaaaa + ca tta ttttgca a - humanchr1/239220001-239550000 304060 TTTTAGACTATA-GTTAAGTGGGAAAAAATACACTTATTTTTGCATTA 304106 - 334444443333.356788*************************9766 PP - + [No targets detected that satisfy reporting thresholds] Internal pipeline statistics summary: ------------------------------------- -Query sequence(s): 1 (330000 residues searched) +Query sequence(s): 1 (59940 residues searched) Target model(s): 1 (80 nodes) -Passed MSV filter: 1 (1); expected 0.0 (0.02) -Passed bias filter: 1 (1); expected 0.0 (0.02) -Passed Vit filter: 1 (1); expected 0.0 (0.001) -Passed Fwd filter: 1 (1); expected 0.0 (1e-05) +Passed MSV filter: 0 (0); expected 0.0 (0.02) +Passed bias filter: 0 (0); expected 0.0 (0.02) +Passed Vit filter: 0 (0); expected 0.0 (0.001) +Passed Fwd filter: 0 (0); expected 0.0 (1e-05) Initial search space (Z): 1 [actual number of targets] -Domain search space (domZ): 1 [number of targets reported over threshold] -# CPU time: 0.21u 0.01s 00:00:00.22 Elapsed: 00:00:00.22 -# Mc/sec: 117.29 +Domain search space (domZ): 0 [number of targets reported over threshold] +# CPU time: 0.00u 0.00s 00:00:00.00 Elapsed: 00:00:00.00 +# Mc/sec: 7920.43 // [ok] diff -r d92dd2f040cd -r be072920a53e test-data/MADE1.out.domtblout --- a/test-data/MADE1.out.domtblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/MADE1.out.domtblout Wed Jul 21 14:10:08 2021 +0000 @@ -1,17 +1,13 @@ -# --- full sequence --- -------------- this domain ------------- hmm coord ali coord env coord -# target name accession tlen query name accession qlen E-value score bias # of c-Evalue i-Evalue score bias from to from to from to acc description of target -#------------------- ---------- ----- -------------------- ---------- ----- --------- ------ ----- --- --- --------- --------- ------ ----- ----- ----- ----- ----- ----- ----- ---- --------------------- -MADE1 DF0000629.2 80 humanchr1/239220001-239550000 - 330000 9.3e-18 51.2 26.3 1 4 2.4e-10 2.4e-10 27.4 0.6 1 43 174456 174498 174456 174520 0.93 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon -MADE1 DF0000629.2 80 humanchr1/239220001-239550000 - 330000 9.3e-18 51.2 26.3 2 4 1 1 -8.4 5.8 12 79 197274 197341 197272 197342 0.86 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon -MADE1 DF0000629.2 80 humanchr1/239220001-239550000 - 330000 9.3e-18 51.2 26.3 3 4 1.3e-12 1.3e-12 34.8 0.7 2 80 302388 302466 302387 302466 0.87 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon -MADE1 DF0000629.2 80 humanchr1/239220001-239550000 - 330000 9.3e-18 51.2 26.3 4 4 0.033 0.033 1.4 0.4 27 74 304060 304106 304029 304108 0.71 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon +# --- full sequence --- -------------- this domain ------------- hmm coord ali coord env coord +# target name accession tlen query name accession qlen E-value score bias # of c-Evalue i-Evalue score bias from to from to from to acc description of target +#------------------- ---------- ----- -------------------- ---------- ----- --------- ------ ----- --- --- --------- --------- ------ ----- ----- ----- ----- ----- ----- ----- ---- --------------------- # # Program: hmmscan -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SCAN -# Query file: /tmp/tmpqydies2m/files/5/d/3/dataset_5d34ccc7-9920-470e-9f13-678ab2ecd29d.dat +# Query file: /tmp/tmpgjabmh94/files/d/c/f/dataset_dcfa47ad-e0da-4c8c-a808-c5bbd7eb2eda.dat # Target file: localref.hmm -# Option settings: hmmscan --tblout /tmp/tmpqydies2m/files/1/d/a/dataset_1da10e33-3e1c-48fc-abfb-7e3c263ec0df.dat --domtblout /tmp/tmpqydies2m/files/7/2/3/dataset_723f3cf1-e0de-4616-aec7-dd16680f3be3.dat --pfamtblout /tmp/tmpqydies2m/files/7/3/4/dataset_734c7f25-0a22-431b-9a7a-58849fcd6009.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 localref.hmm /tmp/tmpqydies2m/files/5/d/3/dataset_5d34ccc7-9920-470e-9f13-678ab2ecd29d.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/8/working -# Date: Thu May 14 18:53:22 2020 +# Option settings: hmmscan --tblout /tmp/tmpgjabmh94/files/9/8/3/dataset_9834554f-8f1e-4161-9c16-f4bd5042207c.dat --domtblout /tmp/tmpgjabmh94/files/8/e/b/dataset_8ebf81cb-d0c9-41a3-a725-c9e2f0d65d82.dat --pfamtblout /tmp/tmpgjabmh94/files/1/f/0/dataset_1f08bd39-0984-447e-b71e-7bf3442d708d.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 0 localref.hmm /tmp/tmpgjabmh94/files/d/c/f/dataset_dcfa47ad-e0da-4c8c-a808-c5bbd7eb2eda.dat +# Current dir: /tmp/tmpgjabmh94/job_working_directory/000/3/working +# Date: Fri Jul 16 11:01:18 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/MADE1.out.pfamtblout --- a/test-data/MADE1.out.pfamtblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/MADE1.out.pfamtblout Wed Jul 21 14:10:08 2021 +0000 @@ -3,24 +3,19 @@ # # name bits E-value n exp bias description # ------------------- ------ --------- --- ----- ----- --------------------- -MADE1 51.2 9.3e-18 4 8.6 26.3 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon # Domain scores # ------------- # # name bits E-value hit bias env-st env-en ali-st ali-en hmm-st hmm-en description # ------------------- ------ --------- ----- ----- ------ ------ ------ ------ ------ ------ --------------------- -MADE1 34.8 1.3e-12 3 0.7 302387 302466 302388 302466 2 80 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon -MADE1 27.4 2.4e-10 1 0.6 174456 174520 174456 174498 1 43 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon -MADE1 1.4 0.033 4 0.4 304029 304108 304060 304106 27 74 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon -MADE1 -8.4 1 2 5.8 197272 197342 197274 197341 12 79 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon # # Program: hmmscan -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpqydies2m/files/5/d/3/dataset_5d34ccc7-9920-470e-9f13-678ab2ecd29d.dat +# Query file: /tmp/tmpgjabmh94/files/d/c/f/dataset_dcfa47ad-e0da-4c8c-a808-c5bbd7eb2eda.dat # Target file: localref.hmm -# Option settings: hmmscan --tblout /tmp/tmpqydies2m/files/1/d/a/dataset_1da10e33-3e1c-48fc-abfb-7e3c263ec0df.dat --domtblout /tmp/tmpqydies2m/files/7/2/3/dataset_723f3cf1-e0de-4616-aec7-dd16680f3be3.dat --pfamtblout /tmp/tmpqydies2m/files/7/3/4/dataset_734c7f25-0a22-431b-9a7a-58849fcd6009.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 localref.hmm /tmp/tmpqydies2m/files/5/d/3/dataset_5d34ccc7-9920-470e-9f13-678ab2ecd29d.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/8/working -# Date: Thu May 14 18:53:22 2020 +# Option settings: hmmscan --tblout /tmp/tmpgjabmh94/files/9/8/3/dataset_9834554f-8f1e-4161-9c16-f4bd5042207c.dat --domtblout /tmp/tmpgjabmh94/files/8/e/b/dataset_8ebf81cb-d0c9-41a3-a725-c9e2f0d65d82.dat --pfamtblout /tmp/tmpgjabmh94/files/1/f/0/dataset_1f08bd39-0984-447e-b71e-7bf3442d708d.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 0 localref.hmm /tmp/tmpgjabmh94/files/d/c/f/dataset_dcfa47ad-e0da-4c8c-a808-c5bbd7eb2eda.dat +# Current dir: /tmp/tmpgjabmh94/job_working_directory/000/3/working +# Date: Fri Jul 16 11:01:18 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/MADE1.out.tblout --- a/test-data/MADE1.out.tblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/MADE1.out.tblout Wed Jul 21 14:10:08 2021 +0000 @@ -1,14 +1,13 @@ -# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- -# target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target -#------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- -MADE1 DF0000629.2 humanchr1/239220001-239550000 - 9.3e-18 51.2 26.3 1.3e-12 34.8 0.7 8.6 4 0 0 4 4 4 2 MADE1 (MAriner Derived Element 1), a TcMar-Mariner DNA transposon +# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- +# target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target +#------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- # # Program: hmmscan -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SCAN -# Query file: /tmp/tmpqydies2m/files/5/d/3/dataset_5d34ccc7-9920-470e-9f13-678ab2ecd29d.dat +# Query file: /tmp/tmpgjabmh94/files/d/c/f/dataset_dcfa47ad-e0da-4c8c-a808-c5bbd7eb2eda.dat # Target file: localref.hmm -# Option settings: hmmscan --tblout /tmp/tmpqydies2m/files/1/d/a/dataset_1da10e33-3e1c-48fc-abfb-7e3c263ec0df.dat --domtblout /tmp/tmpqydies2m/files/7/2/3/dataset_723f3cf1-e0de-4616-aec7-dd16680f3be3.dat --pfamtblout /tmp/tmpqydies2m/files/7/3/4/dataset_734c7f25-0a22-431b-9a7a-58849fcd6009.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 localref.hmm /tmp/tmpqydies2m/files/5/d/3/dataset_5d34ccc7-9920-470e-9f13-678ab2ecd29d.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/8/working -# Date: Thu May 14 18:53:22 2020 +# Option settings: hmmscan --tblout /tmp/tmpgjabmh94/files/9/8/3/dataset_9834554f-8f1e-4161-9c16-f4bd5042207c.dat --domtblout /tmp/tmpgjabmh94/files/8/e/b/dataset_8ebf81cb-d0c9-41a3-a725-c9e2f0d65d82.dat --pfamtblout /tmp/tmpgjabmh94/files/1/f/0/dataset_1f08bd39-0984-447e-b71e-7bf3442d708d.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 0 localref.hmm /tmp/tmpgjabmh94/files/d/c/f/dataset_dcfa47ad-e0da-4c8c-a808-c5bbd7eb2eda.dat +# Current dir: /tmp/tmpgjabmh94/job_working_directory/000/3/working +# Date: Fri Jul 16 11:01:18 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/dna_target2.fa --- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/dna_target2.fa Wed Jul 21 14:10:08 2021 +0000 @@ -0,0 +1,1000 @@ +>humanchr1/239220001-239550000 +CCAAAAATACGAAAAAGTAGCCAGGCATAATGGCACACATGTGTGGTCCCGCTGCTTGGG +AGGCCGAGGTGGGAGGATCGCTTGAGCTCGGAAGGCAGAGATTGCAGTGAGCTGAAATCC +CACCACTGCACTCCAGCATGGGTGACAAAGCAAGACTCTGTCTCACCAAAAAAAAAAAAA +AAAAGAAGGAACTGGCAGAGTCCCAACTGACAGGTATATTTTCTGTTGACCAAAATACGG +TTCTTACTGATATTTGATACTGACTCATAGTCACAACTGCCATATGAAAAGAGAGAGATC +ATTTTTTTTTCCTGGCAATATGTGATGGTGGAAGATACTTAGTGTGGTGTCCTGATAAGA +TAAGTAAGCAACAATGAGGAGGGAACCCCAGGGAGGGAGGACCATTGTTCCGAGAGAACA +GCTAATCACAGACAACCTGTTGGCAGGACATCCTGTTCCCAAATGCCTTGCTTGGCAAGT +AGGCCCAGCAGCAGGACCTCATTGTGCAGGTGGCCCCCTCCAGCATGATCCTATAAAACT +TCCCTCCAGCCCCCGCCTCTTGGCGGACAGACTTCTCTCTGCTGCACTGCCCATTGCTTT +CTTGCAATCTTTGTACTTTCCCTAATAAATCTGCCTTTCCTTACCCATGACTGTCTGTCT +TGGTAAATTCTTTTACCTCCCACGACACCAGCCACAGCCAGTTGCACTCACAGCACTTAG +GAAAATAAAAAAAATCAAGGCTGACACTCTGGATACCAATATGTAATGAAGTGTTCTTCT +TACAAGAGCTTATGAGATAAATAGAAACGTAACAACAATTTTTATTAAGCAAGATATAAA +AACTTCACCATAGGCTGATCCTGTTTTCATTCATGGAAGATAAATACTATCCCTCACTTA +AGAGCTTTTTGTGTAGGAATTCTTCTTCCTTATTTTTTCACGAATAAAGATAGGGATGTC +CTTAGCATCCAAAATCAGTCAAAAAAAAATTGACATTTCATGTCCTGGTTAGACTACTCT +GGCAGCTTGCTGGAATGGTCACTTGCTTCTCCCAACTGGATCTCAAGTCCAGACCCCTTT +GTTGTCGGCCCCCCTCCTGGCCACCCCCACCACAATCACTTAATAAGAAATACCAGCTGT +AGAGCTCAGAACTGCTATGACAATTAAAGCTTCCCACCTTCATGAAAACTGTTGAAAATG +GGGCAGAACAAAAAGTAGTGTGACAGAATTTCTCTATACTGTCTGATGCATTGCTTCCAA +TGTAGGGAGACCTTTAATTGGTTCTCTGGCTTTTGGTTCCATCCTATTGTAAACAAAGAA +TCAAAGTATAGTAAGGTTCAAAGAAGTAGGGAGTGCTGAATTTGGCAGATGGCACAAGAC +ATGGTTAGAAAGAAAGCATCCTCAGAGGAGATGAGAATGATGCTGAGCCTTGGCAAATTG +CAAGGAATGCGTAGTTAAGCAGAGCAACTTTTCACAGTCAGATTTAGAGTATAACTAACT +CTGGAATGACGAGACACACAAAAAGATAAATGCTATTTATCACCACTGCTCACAATGAGG +AATCAGTAAGCAGCCATAACAGATGCTGCGCTGCCCAGATCCCCTCCTTAGGACTGAGGT +GCTCACTTGCCAGCTGCAAAGACTCGTGCCTGAGTCTCTCTCCAGGCAATGTTCTCAGGT +CAAAAGGCAGCTGCCCTGCTGGAGGTTATAGCTCCATCCAGCGGCATGCAGAATCCATTG +ATTAGCAGATGTGGGCATATGAAGACAATGTCTTGGCTCAAATTAGAACGGTTCTAAAAT +TGCTGCGACCCTGGCTAGAATTACATTGCAGGTGAGCTTCTTCCTCCATCCAGTCCTGTT +TCTCTCACTCCATTACAGTTGTGATTCCCAAGAGCACTTCACAATAAACCTCCAGCACAC +AGTCTCCTTCTCTGAGTCTCTTTCTAGGAAAGCCTGACCTAAGACAACAGCCTCCCTATG +GCAAAAATGTCCAAATTAATAGCTTCTTTATATAGGGGGCAAAACCACCAGCAACCAAAA +CTTTTATTTAAAAAAATGACAATTGTATGACTAATCAGCGTACATTTAACTTCAGGATTG +AAAATGTTGCATCCTGAGCTTAATTTCCTTGATTTTACTTTGAACACTCTTTGAGTTGTG +TTTCTATTTTTAGACCACAGAATTTAAGATAAATGTGCATAATTTAGAGAGGTTTCAAAG +AAAGGCAAGTCAAGTGATTAAATAATGAGAATAAAATTAGTATAAAAAGTGCCAGGAACA +TTTGGTCTTTTGAAAGGAAGGGCAAGGGGGCCATTTTAATAACAGCCTTCACATACATGC +CTACTTATTCAGATAGACGGTTGTGAGGTCAAGCTGGAGGGGCAGATAGGGATCCGATCA +CTATAGACCCAGATTCCTGCGGTAGCTTCCTACATTATCTCCCAGCTTTCACCCTCCTGG +CAACATCCAGAGTGATCCTTGAGAAACCATAACAAATCACATCGCTCTTCACCTCCAATC +CACCTCTTCACTCTCCATCAGTCCTTCTTATGAACTACACACACTCTGTGATCAAGCCCT +GGCTGCCTCTAGGGATTGTCTCCTCCCATTCACCACTACAAAACTTCTTCCTCGAAGGTG +TCCAGCAGGCCAAGCCACGCTGGACTCAGGGATCTCCCCACGGCTGTGTTCTTCCCATAG +TACCACAAACCCTCCACTCCATTCACTTATCTGCTCAATGGCACCTCCTGTGAAAGGATT +TAAAGTAGCCCTCCTCGTGATGTTTTATTCCCTTACTTTGCTTTACAAGCCATCAGAGCA +TTTATTACTTCTTGATATTCTAATTCTAATATGCTAACGTTATATTTTCTATATATACCA +TTAAATATGGAGAGAATGGATAGATATAGATTTAGATAGCTGATACAGGTAAATATAGAC +AGAGGTAAAAATATAGATAGAGACTCTTTCATTTAGTCCTACGTGCCCATCAAAATGTAA +GCTCCGTAAGGGTAGGATCTTTGTCTCTTAGTTAACTCCTCTATGGTGGAGGAGATGTGA +GACAACCAGAAATTTCTGTCTAAAAAAAAAAATCACACACTCGATCACACACTCGATAGG +TGTTCAATCAATATTTGGTGACTGAATGAATGGATGAATGTGATCCCTTTAAATCTGTAT +CCTCACTATACAAACTTCCTTAAATATCTATTAGGTAATTTAGCTAAACTTTTCTTACTC +GCTCCAGTGTGGTGTGTGTTTGTCTTTTCTTCCTCCTTGACCTATAACTATTGACAGTTA +TACAATATGGTGGTTCCACAGCCACCAGCCTCCTTTTCCTATTCTCTAGAAAGAACGAGG +ATGAGCTATAAAATTCATCTAACCCTATCATCTTTTTAAGGGGTATAATATTAAGTGGAA +ATTCTTTACAAATTTAAAGTTATATTCAATTTGTAAATAAGAATAATTATTATTGCCTGT +AACTTTTGAACTTGGCCCATCTCGTTTCTGCCTTCTTGAAATTCGGTATTTTTTATTAGA +GCTTTCAGAGTCAGCTTTTGATTTTATTGATCTTTTTTGTTTTGTTTTTATTTATGTTCT +TGTCTTTTTAACTTACATTGTGTGTGTATTCTTATTTATGTTCTTGTCTTTTTAACTTAG +ATTTTTGTATGTATTCTTTTCTTTATTTCTACCTCCTACAATGGAATACCCAGTTATTTT +TTATATATATGATATATATATGGCATATATATGACATATATGTATGTCTTTCTTACTTAT +ATTTTTAAGTCTTTACTTCTAACTTCTAGAATGGAATATATATAAACCAAATATTTGAAG +CAGCCTGTGTATTATGGATAAATATTTCTCTTGGATAGACACCAGTAAGTTTTATATATA +TATATATATATATATATATATATATATATATATATATATATACACACACACACTCACACA +CACACACACACGATTAAAATTCTCTTGTTTTTAATACATGTGGGTATGACTATGCATTCT +TCTGTAAATACTACTTTATCTCATAAATGTTAATGAATAAGAAGTTTATTGTTTTGGCTT +TAAGTTCATTTTGATATCCACTCTAATTCATTAATTCTTCAGTCACATATTGTTTTAAAA +TACATAAGGTGTTATTGTTTTTAATTTTGGTATGTATTTTAATCGTGGTGAGAGACTATT +ATCTGCGTTATATCATGTATTTGACATTAGCTGAGACTTCCTCAGTGACCATCAATATAA +TCAATTTTGAAAATGTCCAAAAAAAAAAAAAGGGGGGGTTCCCTCTCTTGGCTTTGGAGC +CCCCCTCCCTCTGTCTCTGTTCAGGGGGGAGCGTCTTCCTTCTTTCTTCCCCCTTCTACC +TTGCCCATTAAACTCTCTGCTCCTTAAAACCAAAAAAAAAAAAAAAAAAAGGAAATAAAA +TGTCTTCTGGTTTCTTGAAAAGAAAATATCTGCATTTACATTGTGCAGTGTTCTGTGTAT +TTTTAAGTTTTTTAATTATATTGTTCAATTCTATTACACACTTAATATTTTGTATTTGCT +TGATCAGTTTCCAGTAGACTAATATTAAAATCAATATTATAATAGTAAGTACATCCTCAA +GATCCTAAAGGATTATTTATTTTTAAAAATGTTTTATTTAGATAGTCCTTACTATGTTCC +AGACATTCTTAGCACTTTGCACATATTAACTCACACAACGTCACAATTGTTGCATTTTCT +TGGAGGATTTTTCCAATTGTTATTAAATACTTTCCCTATCACTTTGGATTAAAATTGTTG +GAGTTTTTAAATAAGAGGCTTATAACATATAATTATTGTCTTAGCCATGATGCCTTTTTA +CAGGTAGTTTTTAGCAGTAGTAGTTTTAGTGTGAAAGTCTGGATATTTCAGTCTCTTTTA +CCTTGCCCTCATTCTTTTTTTTCCCCCTCATTCTTAAAGCATATTTTACCAGTGCATAGA +TTTCTAAATTAGATATCTATTGTCTTTTGACGTCAAATCTACTATTACTGTCATTGCTGT +GGCTTTGCAGACAACCTTTTTTTAGGTAGTTTTTAAGAAACTTTTTTCTTTATCCTTGAT +ACTGTGAGATTTCACTGCATTGTGTCTAGGCGTGGGTTTATTTTAGTTACCTTGCACGAT +GCTTGTATTAGTGAGCTATTGTTATGTAAAAACTCAAACTCCAAACTCAACAGTTTAAAA +CACCGTCGTTCATTCATTCATGCGCATACATTCACAGGAAGTTTGGGGATCATCTGACCC +AGTCAGGATTTGGCAAGGCATACCACGAAGCTGTAGCTTGGGGTCAGGAGTAACATTTCA +CATCTTTCCACCTATGGACAAACCCAGACACATGGCCAATGCCAAAGTCCAGAGGTAGGA +AAGTACACTCTCCCTCTAAGCAGAGAAACTACAAAGTCTGACAATAGGCAGGTTACAATA +CGGGGGGCAAGAATTCATTCTGCCATACTCTTTGATTTCAGTCTGAAAACATATATATCT +ACTCATTATCAAAAAACATTTAGTCTTCATCCTTTTTTTTTTTTTTAGATGAAGTCTCCC +TCTTTTTGCCCGGGTTGGAGTGCAGCGGCACGATCTTGGCTCACTGTAACCTTTGCCTCC +CAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGTACGTGCC +ACCATGCCCAGCTAATTTTTCTATTTTAGTAGAGACAGGGTTTCACCATGATGGCCAGGC +TGCATCCTTTTGAATATTGTTTCAAACTATTCCCTCTATTTTCAGCTTTTGTAGCTTCTT +TTAGATGTATATTTCAGACTATCAAAATGTCCTCAATGTCTCTATTTTATTTTTAATAAT +TGTTCTATTGATTTTGCATCCTTTCTATACCTGACAAGACAATGAAATTCTGCTAAAGAT +TTTCTTTTGCCTTTTTGGACTTCCTAAAATTTACATTTTATTTAAATTACGTAAATAATA +AATAATATAATAACATATTTATTTTACAGAAATCTTATGATATATACAATTAAGTCTCCA +TCAAATTTTTCCTAGCTCTACACTGACCTCTAAAAGTTAAATACCCACTCCAAAGATAAT +CACTCTTATGTATTCAGCATATATTCTTTCTGATCTATCTGCTGGAATATATGTGTGTGT +GTGTGTGTATATATATATATTTATTTATATACACACACGAACATAGAGGAATATGCATTT +GTTTATGAGAACCTTTTTTTTCACATATGTGGCTATAATTTTCATGTTTTTAGGAGACGT +TTAGGTTTTGTGGAGAGTGAAGAAAAATTTGGTCTAAAGGCTTGACGAAGCCCCATGCAA +GTGAAGGGCTCTCTGCATTTTACACGTCATTTCCTTTGTGGTAAATCTGCTCTTCTGTAT +TTCTGTAAATGTATCTTCTGCACTTTGTTTTTTCACTAAAAAATTTACATTGGCTATCTT +TCCATTCCTAAAACAAAAATCTAGCCAACATAACTCATTTCAAATATTGCATATAAGTGG +TTTTATCGGTATTAAATCATCATATTATAGCTCTTAACCAAATGTTTGAAGCAGCCTCTG +GGTTATGGATAAGTAGTTCTCTGGGATAAACAGCAACGAGGCCAATGCTTTTATGAAAGA +TATATATTTGTAACTGGAATATATACTGTGAAATTGTTCTCAAAAAAGCTGTTCTATTTT +ATACACTTGCCAATAATTGATATTATTAATCATTTTGCCTAGCTTTAAAGCATTGTACTA +ACTGGTACCTCTTAATGCTTTGAAGTCTATATTGATAAATTTAATTTAAAAGTGTGTTTT +TCTTTGATAACATAAAGGAAACTGGAGAGGTGAGATGGAGAATAAAAATAAGACATATAT +TATTTAATGAACTTTAAAAACAAAACCCTAAATGAGATAAGTCCCATTTCACTACTTCAA +AAAAATATATAATGCAAAGGGAATACTTATACATACACTTGGGAATACTCTGGAATTATC +TATGAATGCTGATGATACACATAAACCTAGTCTGCCCACAGTCTCAAGTCATTTGTAGTC +CTAACATTCCACCTCATTTGGTACTTGCCCCAGTATTTTTTTCATTTTTAACAATAATTT +TTATTAATTGTTGCACTTAAATAATCCAGATGGACTGGAGAAAACTCCACTTTGTATTTT +CAGCTTCTCATATGCTCTTTTCCACCAGTATATGAGACACATTAGCAGAAAACAAAATTC +TTATGTGAACACATGCTGAAATCTGAAAAAAAATAATAAGTGAGAACTAATCTCTAGTTC +TCAACTCTTTCCAGATACACTATAGCTAATACCTCACTTTCAGTAACAGTATAAAGTGAA +TTCACTGATAATAACCAGTGCAGCTAAGTCCTTCTGGTCTAGGGCAGTGGTCGGAGTGGT +GTTTAATATCGGTGCCCTTGCAGCCACTTTGCTTACCAGCTAGTTCTCCCTGAACCAGTA +CTGCAACCTGCAAGAGTCAAAAGCTTATAGGCAACCCATTGGTGAGGTCAGTGGGAAATG +CAGGGAATGATAGTTAAGATAGAAGTGACACGTGTGGGAAATAGAGACTGGGACATCCCG +CCATAGAGTTCTAAAAACAATTTCAATATTCTCGCTACAGTTCTTTTAGTATTTATCATA +TGCCGTATATCTTCAACTATTTATTTTACGTATTTGATTGCTTGATATGTGGGACCAACC +CCTTTCAAGAGAAATGACTCAATGTCAAAAGTTACGTATGAGCTGAGAGTAATATAAATA +AAACATTAAGTCTGAAATTTCCATTTCATAGAACGTTTAGAGAAACTTTTTAAAAATATT +TATGAATACTTACAATCTTCCTATGTGCTATAGTAACATTGCTGTCCACATTAAAAAAAC +AATATGACATAACTCTGTTGAAGGAAACTCAACATCCACTTTAAAGTTAGTACATTTAAC +AAGGCTGCCCTCAAAATGATTATTTAACACATAAAAATAAAGAAGATGCATTTACATGTA +AACCATGTAAGTCTGTGAAGCTTGAATTTTTCATTTAGATCAAACGACTATTTCTTAAAT +AAATTCTGCTTGCGTCCATGTTCTATTGTGAATTATTAAAAAGTGAAGTAATAACTGTTA +AGGTATTAACTTCATTGGTAGAAAAACTTTATAGTTAAAAGATTGCTGGTTTTATCAATT +TCATCAAATGCTTTGAATACAAATTGGTTAAGTTTATTCCAATAACATTGTTTTTACATT +TTTAAAATTTTCATTCATGAAGTAGAGGAAAGATAAAATTATTTAGGAGTTCATTCTGAC +AAAGGTGAAACATCCAACTTTACAATAAATATTTTCATAAGTTTATCAAAAAGTTTAACA +CTGAATAATAGTAAAATTACTCATTTTGTGGTAATAATAAAAATATAAATTTTGATGGAA +TACAGCATCACGGTAAACACGATTTTCTTGCTAATTCAACAAACCTGGGAAGCAGAAATG +TACTTGGATTTGCAATGCATACAAAATTCATAATTGCATGTAAGCAAGTTATAATATCCC +AATGGCTAAATAGAAACTCTGTTTGTCTTTTTTTTTTTTTTATCACACACACAATTTGAG +TAACTAAACTACAACATTTTTATGATAAAGTTGATGTTGGAAACAAACCAAAAAATCATT +TTTCAGCATGGCAATGTGCTCCACTCATTGGATTTTACAAATGTCTGAACATGTGAAGAA +TTATTTCATAAATCAACTTAAACATGTGACAATTGTATTGAGCTTTTTTTTTGGTATGTG +GGTACTCTAAAGATGAGTATCCTTTGTTTTTGCAAAACCAGTAAAAATATTTAATAAATT +TTTTCTATAAATGTAGTACCAAAATGTTTGAAGTTTCTACTGAACCATTGAAAACAAAAT +ACGTAAGCAGAAATATATGACAAAGTCAAGAGAGAAACTGAACAGATTAAACAAAGGACA +TGCAACGTGTTATATGATTTCATTTCTCAATTTTATAATCCCTTTCTATAATATCTTGAC +TTGCAGAGAAAATTTTTGTTGGAGTTTCTATGTTTAATAAAATAAATGGATATATTTACT +AGAATGAAATGAAATTAGGAAGGCCTATGATTTTGCAGCATAAACGAAGCAATTTATTTT +AATTGCTTTTTCCTAATTAAACTAAGAAAGGTATACATAGAAGGACAATATCTGTAAAAA +TATTTAGCATACAGTATTAAAAATTTTCAATACACAATATTCTCCAGAGAGCAAAAGTTT +CTCTGAGTGTAGAATTTATATCAATATCTGTGAAGATAATATTTTTCTCAATTATAGATG +AGTCAAAAATTTTGAAATTTATTAACCCACAAGATCAAATTTCAAACTTAAAACAATTTT +ATGAAAAAAAGTCCAAAAATAGTAAGACCAAGTTGAAAAAAATACATTTAATACACAAAT +GGTGATGACTCAATTGATTAGTATAAGTTAATATCTCTAATACTTGATTAACTATTTCAT +TTATCATAAGCCCATTTAAATGAGTGGACTTTGTCCTAATTGTCTTCAGTGTAGACAAAT +GTTATTATATTTTAGACATAATTTGATCTCTGAAAACACTTTTAGGATAAGACTATTGAG +TTGGCAAGCCAATATATTAATAATCAATTTATCAGTCAATATCTTAATTCAAGCTACTAT +AACAGAGTACCATAGACTGGGTGGTTTATAAATAACAGATATTTATTTCTCACAGTTTTG +GAGGCTGAAATTCCAAGATCAGGATATAGCATGGTTGGGTTCTAGTGAAGGCCTCTTCAC +TCAGAAGACTACTGTCTTTTTGCTGTATCCTTACATGGTAGAAAGAAGTCAAGAGAGCTC +TCTGAGTTCCTTTTTATAAGGGCATTAATCCCATTCATGAGAATTCCACCCTCATGACCT +AAAAACTCCCCTATTCCCCACCTTCTAATAGCACCCCACTGGGGTTTAGGATTTCAACAT +GTGAATTTTGGAGTCACAGACATTCACTCCAAATAAGTTAGTAAATACCAGTTTGATTTA +CATAATGTCAAGTATTTGATAACGCCCTTTAACTCTCAAAATGTCCCTATGTGTACAATA +ACTTACATGGTAAATTTGCCTATGATTGAGTAATTCCTTTCTTAGTTATTTACCCAGGGG +ATTGCAGGCACAGCAACACTAAGAGACAGGTTAAAAAAATGTTCACAGCTATGTCATAAT +AACTTAAAATTAGGAACAATCCAAATATCCAAACACAACAGAATGGATAAATAATATAGT +TTAGTCTTAGCATTGACTGGTATGGAAATTAACAGGAAAAATGCAACTATGTGGATAAAT +CACACATATATACCACTAAGGGAACGAGATTAATACAAAAAATATATAGTCTATGAAAGA +AATATAAATGTCAAAATGAGACTACACTGTCACTATTATTCAAACATCTGTACACAGTGA +AACTATATAAAAAAGAAAGAAAATACTGACCACAATTTCAAGATTGTTGTTACTTATAAG +GAGAGAAAAGAGTCAGCAGTTCTGGGGCTCTGAAAGTATTCTATTTCTTGACTTTGATAA +GGTTTAGACAATTGTTGGCCTCATTTTTTTTAAAAAAAGCCTACATTTGAGGTTCATTTT +GTTTTTCCTGTATATGTGCCAAATTTTAATTTTTTAAAAAAAGTAGGTGAACAATCTGAA +ATTAAAAGTTTTTATTCTAAGGCCTCTTTGTCATTTACTAGAGTAGTTGATACTTTTAAA +ATGTAAAGCTGTTAAACAATTATAAATTATATTTATATCAAGGTGATTTTCCCAATCTAG +TGAGCACATGTGAATATGTATGTATCTAATCTAGTGAGCATGTGTGAATATGTATGCATC +TGTTGGGGGGAGGTTTATGTGTGTGCCTATGTGTTTGCTTTTTATGTCTGTGTAGTTGTA +AGCATGTGTACATGTATTTAGGTGTGTGCATTTATTTGTGTGCCTGTCTGTGTGTGCATG +TATGTTTTGTAGGAAGGTGAGGATACATTTTTTTTTGGTGTAGAAGATATGATCATCACA +GAAATAATTAAAATGAGCAGGTTTTTGAAAATAAAAACCCCAAAACAGAAATAAAATTTC +AAGTAAATGAAATAAAATGAATAAATATATTTTTTCATCAAGTTAGATGTTTCAAAACAC +AGACTTCAATGTTAGCTTATTTCCAGCTTTTTGTTTTCTCAGTATGTGGTTCACGCAGCT +ATAATGCTTTTGAGAACACAGAGCGCCAGTTGTGGGAAAAGAAGCTCTGTTCATTATCCT +CAGGTTGTCTTCATTTCGTAATTCTTTTCACTACCTCTTTATGAGTATTATCACAAAACA +AAAACAAGAAACACCTGCTGTATTGTACACATGATTTTCAATCAATTCATCAGCAGCTTC +AGAGTAAAAGAAAGAAATCAAGCAAATTATTAGTCCACTTGGGAACTATGAGAACACATT +TAAAGGATGTGAATATTTTCATTTCAAAGTAATTTTGTTTCTTTGCCTTTTGGAATCATC +GGCACCAAATGCTTTTTGGCTTGCTGCTTACACTTTTCATCATCGCCTTTTAGATATTTA +TTGGAAAAAGGCTCTGAATTTTGGGGGCTGCGAAATATGAAGATGCACACAAACACACCC +CACATACAAAGATATAATGTTCATTATAATGTGACCATTAATTCTGCCATTCTTTCAAAT +TCTGAATTCACTTCTTTAATCCTTTCAGCTTAAAATTTGATATTTTGATTCTTGGGTAGA +AAAATTCACTTAAATATAACAAAGATTTATTGAACCCCTGTTATATAACATATTGGATAA +ATGCTCTAGCTCTGAAGTTTACAGACCTGGTTTTGAATTTTAGCTCTACAAATAATTATG +TCAGCTTTGGGCACATTGCTTAACTTCCATTCAATTCCATTTCCTCACCTGTAAAACAGT +TACAGTGTCCTGAGATAAAACATTAGTAACCCAGAAACAAGCATAAAATCAAGAAAAATG +AAATTATTATTAGAAAGGTAGTCATGTAACATTACTGAGCAATTGTCACATCCTCGACTT +TGTATAGTAATGCAAACATTTGGTGAAAACTTTTGTGTTGCTTTCAACTTACATGAATTG +AATGCCAATCAGAATATTTCTAGGATTACATCAAAATTAGTACATAAATTGTGATAAGCT +GAGAAAATAACTTATTTTTTCACCAAAACAAGTTACCCACATTGTATTTTTGCATTGCTT +AATGTATATATAAATGCAAGCCATATACCAATTACTAATAAATGCAATAGAATAGGACAA +ATTCAAAGCTCTTCTCTCTCTCCAGTTCCAACAGGAAAAAGAAATCCATTTTTATTTTAT +AACATTGGCTGAGTAAAAAAAAAAAAAGTGAATGAAGTAAAAAGATAGACCTTAATGTTT +TAATATAACATAATTATGGAGTTCTATTTTTTAAAAAAATTCATAATGCATGGAGTTCAT +TTTATAAATACATATTAATATCTATAGCATAGTAAAATTAAAATAGAACAAGTATTTATC +TTGAGAATTATGCTGTCATATTCAAAGTCCATATTGAATTAGAAAATGTTAAGCTCAATC +TTTCTAGCCATGGAGATTGATAGGTCATCAGATCATCTAGTGTAATCATCTATATGATCA +GCACCTCTGTTGCCTCGTTCAGCACAACAGATCAACTAGAAGTTACTAGTTTAGGTAACA +GGTAAAGGGATCTCACTGGAGGAGGACAATCACAACCAAACAAATAAATGAAGACTGTGA +TGAACCAACCAACACTGACAGCAATCAGTGAAAGTCTGGGATAATTCCCCAAATTCTGAA +TCCTGGTGTTTTTCTTAGTAAATTGATGTAGTAATTATTGTGGTGACTATGTGGTCTGCG +TTTTTACTTTTAGTCCAAATTTGCTTCTTTCAGGGAAGTTATGGGCTTGCTACTCTGGAC +TATGAATACTGAGGCCCTCATGCAGATACAAAGGAATGTCCTGTTATAGTCTGTGATATG +GTTTGTGGACAGCCTTGCTTGTGGGTGCAGGGAATTAAGAGCACACAAGTACTAATGGAA +TAAGAAGGTAAGCATGATATACTCTGGAGTTCAATATTCTAACCTTCTTCTTGAAAACAA +AATTAGATATAAAAGTGGCAGCAACTCTGGTAAAGTCATGGGAAAAGAGTACTGCCAGTG +ACCCTGTTATTCCAGCAGGATCTCATAGAGCATGCCATTAACCTCAGTCCACAAGAGAGT +ATATTATACAAGGAAGCAATTAAAAATGGCTGGTGTCTAATCTCTTGTGACTTTTGGGTG +CTGGATTTTCCATAAAACAAAGGCACATCAATTTCACTGAGGAAAACTCCACCCTTCAGG +GACTTAGTTTGGACTTGCTCCCATTGATGTGTGGAAGTGAAAAAGTCAGCTCTTTGTTCT +TGGTGTTTATTGGTTTATCACAGTCATCATTCTCTTATTCAGCAAACGTTTATGCAGAAA +TGTCTATACATAAGGCTTTGATTTAGGTGTTCAACTACAAGTGAAATAGACATTTTCTTC +TTTGTTAGAGCTTATTGTCTAGAGGAATATGGAGATAACATACAGGTAAATGATCAAACA +AAAATATGAAATAACCTGAGAATGATGCTATGATACAATCAAATTAGAAGCTAAGCAAAT +AATTAGAAGGAAAGAACACATGTGAACAGCTTAGACAGGTCGGAGCTCTCGGAGGAGTTG +GAATTTGAAGACCTTGAAGGAGCTAGCCATGCAATGTGCAGGGAGAAGGAAGAGAGGCAG +GCTCAGGGGCTCTCATGGTGTCCTATCAACTTTATGGTGATGTTCACTAAATCTATATAA +ATTTTCTTGACATCACCAAAGTCTTCAGGTTAACAATATGAACTGTGTTATCCAATTAAT +TATTTTACCATCATCACAAATAAATATACAAAACTAAATCATTATGTCATCATCCCATGC +TCGAGAGTGCTCCACCTCAAAACTCAAATTTTCTATGACTAGCTGTGTTTTATTTATTAT +TCCAGATAGTATATTTCATAAACATACATTGAAAGACACTATTTAGCTTATAAAACAGAA +CATTAGCAATATTGTTGATGCCCTTTGAGTGCTTCTCCCCAATTTAATTGTCCTTTCTAC +CCACCGAAGCTATCCATTACTTTGTGCTCTGTACTTGTCATTTTTTTCATTGTTGTTTGT +CTCCCTAGTTTGTATCCTTAAATGAGATATTGTTTAGTTTGGTTTGTATTCAAAGCTTGG +TAAATACAAATGTATAGATTCTCCACTGACTTGCTTTATTTTATTGAATTTTATTCAATA +TTATGCTTCTGAGGGTCTGTTAACTTCTGTAGCTATATTTCATTCAATTTCACTGTTGTG +CACAGTTCCATTTTAAGAATTTGCCCAAATGGGTATATCTATTTTTCCATTAACAGACAG +TAGGTGGTTTCCAATTTTTTCTTACAATCAACAATATTACTATGTTCATATTCTTCTTGT +GAATATGAAAATGGTTTCCAGAGGGTATATATTTAGTAGCTAAATTTCTAGGTCTGTGTT +AGATCATGTGCAAATTACTAGGTAATATCATCAGGCTTTTCAAAAAGAATGTACCAATCT +ACATTCCCACAGGCAGATTTCAAATCGTCTACTATTCCACATACCTATCATTTTCATATT +TTTAAGTTTCTTTCAATATATTAGATATAAACAGGTATCTCATTTTTATTTTAAGTTTGC +ATTTCTCTGATGACTCTTGATATTGTGAGCATTTTCATTTGTTTATGAGTCATTGCTATG +TCTTCTATGAAATGTCTGAGCATGTCTTCCGCTATTTCATCTTCTAGACTTATTGTCACT +TCCTTATTGAGTTTTAAAAGTTTATATATTCTTCATATGATTTAATTTTTGAACAGAAAT +TTTACTTTGAATGTAACTAGATTTATAAATACTTCCTTTAAAAGTTTTTGCTACTTTGTT +TGGTTTAGGAAATCTCCATAACTCAGTTAATTTTCTGCTGAAACTTTGAAATTTTGCCTT +TCACATTTGTCTTTGACTTAGGCAAATTACTCCTTTTTGTGTATTGTGTGGGAGAATCCT +ATTAAATATATCTTGTCAGAACGACCTGTGGATCAGCTGTGGCTGTGGCAACCACTGCTT +GTGGAAAGTGGAGGAAAGAGTATGAAGGGTTTTGTATTGTGGTTTGAGTATCAGCTTAGT +CACAGTAGACTAGAACATCAGGTAAATTGCTAAGGTTTTTGACTCGAATCCCTAGCTCTC +AGACAGCATCTCTGGACACATACAGGGCCTGGGGAATCTCACTCCCCTTGAAGGGAAGGA +ACTTAGGCAAAGTCCAGTGCTGTGCAGGTTTCAGGTTTGACCCAGCAGAGTCCCAGTGGT +GATGGCCACAGGGGTGCTTGCATCACCACACACTTAGTTCCAGGTGGCCCAGCACAGAGA +GAGAAACTCCATTTGTTTGGGAGAAAGCAACAGAAAGAACAAAAGTCTCTGCTTGGTAGT +CATGAGAATTATTCTGGATCTTACACAAGATCACCAAGGTGGTACTTCTACAAGTCTGCA +AAACATATACTTATTGGGTTTGCAGCTTAAGTCTCTTTGAATACCCACAAAGCCTTCCCA +GGAAGGACAGGCACAAACAAGCTCAGACTGTGAAGACTACAACAAATACCTAACTCATCA +ATGCCCAGACACAGACAAACATCTACAAGCATCAACACCATTCACAAAAACATGGCCTTG +CCAAATGAAGTAAATAATGCAGCATGGTCCAATCCTAGAGAAACAGAGATATATGATGTA +TCAGACAGAGAATTCAAAATAGCTGTTTTGAGAAAATTCAAAGAAATTTAAGATAACACA +GAAGAAATTCACAATTCTGTCAGAAAAATTTAACAAAAAGATTGAAATAATTTAAAAGAA +TCACACATTCTAGAACTGAAAATTGCAATTGACATGCTGAAGAATGCATCAGAATCTCTT +AATAGAGAATTGATCAAGAAAAAAAATTAGCGTGTTTTAAGACAGACTATTTGAAAATAC +CATTCAGATGAGACAAAATAAAATAATAAAAACAATGAAGCACACCTACAAGATCTAGAA +AATAGCCTCAAAGGGGTTAATCTAACAGCTCTTGGACATAAAGAGGAGGTAACAAAAATA +TAGAGGTAGAAAGCTTATTCAAAGGAATAATATCAGAGAACTTCCTAAACCTAGAGAAAG +ATATCCACATTCAAGTGCCAGAAGGTTATAGAATACCAAACAGATTTAACCCAAAGAAGA +CTACCTCAAGGCATTTAATAATTAAACTCCCAATGGTCAAAGATAAAGAAAGGACCCTAA +ACACAGCAAGAAAAAAGAAACAAATAACATACAGTGGAGTTCCAATATGTCTGGCAGCAG +ACTTTTCAGGGAAACTTTACAGGCCAGCAGGCTAGGAGACAGTGGTGTGACATATTTAAT +GTGCTGAAGGAAAAAAACTTTTACCCTAGAATCATATATCTGATAAAATATCTCTTAAGT +ATGAAGAAATAAAGACTTTCCTAGAGAAGCAAAAGCTGAGGGATTTAATCAATCCGAGAC +CTTTTCTACAAGAAATGCTAAAGCGAGTTCTTCGATCTGAAAGAAAAAGATAATAGTGAG +CTATAAGAAATCATGGGAACGTATACAACTGACTGGTAATAGTAAGCACACAAAAAAACA +CAGACTAATATAACACTCTTCTTGTGGTGTGTAAACTATTCTTAAGTAGAAAAACTAAAC +TATGAACCAATCTAAAATGATAACTACAACAACTTTTTAAAATACAGACAGTACAATAAG +ACATACAGAGAAACAACAAAAAGTTAAAAAGTAGGAAGATAAAGATAAAGTGTGGAGTTT +TTATTAGTTTTATTTCTGCATATCAGTTTGTTTATGCAATTAGTGGTAAGTTGTCATCAG +TTTAAAATAATGGGTTGTATTTGCAACCCTCATGGAAAACTCAAATCAAAAAACATACAA +CAGATATACAAAAAATAAAAAACAAGAAACTAAATTATATCACCAGAGAAAATCACCTTC +ACCAAAAGGAAGACAGGAAGAAAGGAAAGAAGGAAGAGAAGGTTGCAAAATAACCAGAAA +ACAAATAATGAATGAAAGGAGTAAATCTGTATTTATCACTAATAACATTAAAAGTAAATG +GAATAAACTCTCCGATAAAAATACATAGAATGGCTGAGTGGATAAAAATAAACAAGACCC +ATTGATCTATTGCCCGCACGAAATGCAGTCCACCTATAAACATGCACATAGACTAAAAAT +AAAGGGATAGAAAAAGATATTCCATGCCAATGGAAACCAAAAGACAGCAGAAGTAGCTAT +TCTTATATCAGACAAAATAGACTTCAAGACAAAAACTGTAAGAGACAAAGAAGTTCCTTA +TATAATGATAAAGTGGTCAATTCAGCAAGAGATATAATGATTGTTTATATATGCACCCAA +TACTGGAACATCCAAATATATAAAGCAAATATTGTTAGAGCTAAAAAGAGATAGACACCA +ATACAATAATAGCTGTAGACTGCAACACCTCACCTTAAGCATTGGACAGACCTCCCAGAC +AGAAAATTAACAAACATCAGATTTAATCTGCACTACTGAACAAATGGACCTAATAGATAT +TTACAGAACATTTCATTCAATGGTAGAGAATACACATTTTTCTCCTCAGCACATGGAGCA +TTCTCAAGGACAGACCATATGTTATGTCAAAAAACAAGTCTTAAAACATTCAAAAAATGA +AACAATATCAAGCATCTTCTCTGGCCACAATAGACTATAACTAGAAATCAATAACAAGAG +GAATTTTGGAAACTATACACATGGGAACTTAAAAATATGCTCCTGAATGACCAGTTGATC +ACAGAAGAAATTAAGAAGGAAATTGAAACTTTTCTTAAAACAATGATAATGGAAACACAG +CCTACCAAAACCTCTGGGATACAGCAAAAGCAGTACTAATAGGGGAGTTTAGAGCTGTAA +GGGCCTACATCAGAAAAAAAGAAAAACTTTAAATAAATAACCTAATGATGCATCTTAAAG +AACTGGAAAAGCAAGAGCAAACCAAATCCAAAATTAATAGAAGAAATAAAAAACATGAGA +GTAGAAATAAATAAGTTTGAAATAAATAAAACAATCCAAAAGATCAATGAAACAAAAAGT +TTGTTTTTCAAAAAGATAAACAAAACTGAAAAACCATTAGCCAGACTAACAAAGAAAAAA +AAAAGAGAGAAGACCCAAATAAATAAAATCAGAGGTGAAAAGGAGACATTACAGTTGATA +CTGCAGAAATTCAAAGGATAATTAGTGGCTACTATGAGCAACTATATGCCAATGAATTGG +AAATATCAAAAAGGAATGGATAAATTTCCAGATGCATACAACATACCAAGACTGAACCAG +GAAAAAATCCAAAACCTGAACATACCGATAACAAATAGTGAGATAGACACTCATAAAACA +TCTACCGGTAAAAAAAAAGCATGGGAACTGATGGTTTCACTGCTGAATTCTACCAAACCT +TAAAAGAAGAATTAATACCAATCCCACTCAAATTGTTCCAATACAGCAGGAAGAATTACT +TTCAAACTCATTCTATGAGGCCAGTGTTACCCTGATACCAAAACCAGACAAAAACACATC +AAAAAAAGAAAACTACAGGTCAATATCCCTGATGAATATTGATGTAAAAATCCTCAACAA +AATACTAGCATATCAGATTCAACAACACATTAGAAGGATCATTAGTCATGACCAAGTGGG +ATTTATCCCTGGGATGCAAGAATGGTTCAAAATATGCAAATCAATATCATACATCATATC +AACAGAATGAAGGACAAAAACCATATGATTATTTTAATCGATTCTGAAAAAGCATTCGAT +AATGTTCAATATCTCTCCATGGTCAAAACCTAAGAAAACTGAAGATAGAAGGAACATACC +TCAAAATAATAAAAGCCACATATAACAAACCCACAGCTAGTATCATACTGAATGGGGAAG +AACTGAAAGCATTTCCTCTAAGATCTGGAACACAATGAGGATGCCAACTTTTACCACTGT +TATTCAACATAGTACTGGAAGTTCTAAGAGAGCAATCAGATAAGAGAAAGATATAAAGGG +CATCCAAAATTGGAAAACAGAAATCAAATTATCCTGTTTGCAGATAATATTATCTTACAT +TTGCAAAATCCTAAAGACTACCAAAAAACTATGAGAACTTATAAACAAATTCAGTAAAGT +TGCAGGATACAAAGTTCACAAGAATTAGTAGCATTTCTATATGCCAACAGTGAATAGGAA +AAAGAAATCACAAAAGTAATCCTATTTACAATAGACACAAAATTAAATGCCTAGGAATTA +ACCAAAAAAGTGAAAGATCTCTACAATGAAAACTATAAAACATTAATAAAATAAATTGAA +GAGGACCCCAAAAAATGGAAAGGTATTCAATGTTCACGAATTGGAAGAAGCAAAAATTGT +TAAAATGCTCATACTAGCCAAAGCAACCCACAAGTTCAATGCAATCCGTATCAAAATACC +AATGACATTCTTCACAGAAATAGAAAAAAAATTCTAAAATTTATATAGAATTACAACAAG +ACTTGGAATAGTAAAAACTATTCTGAACAAAAAGAGCAAAACTGGAGGAACCACACTACC +AGACTTCAAATTATACTACAGAGCTATAATAATTAAAACAGCATGGTACTGGCATATAAA +TAGACACACTGACCAATGAAACAGAATATAAAACCGAAAAGCAAATTCACACACCCACTG +TGAACTCATTTGCAACAAGAGTGCCAATAACATACCCTGGGGAAAAGACATTCTCTTCAA +TAAATGGTGCTGGGAAAACTGGATATCGATATGCAGAAGAAAGAAATTAGATCCCTATCT +CTCCCTTGTACAAAAATTAAATCCAAATGGGTTAAAGACTTAAGCCTAGGACCTCAAACT +ATGAAACTGCTACAAGAAAACATTGAGGAATCTCTCCACAACATTGATCTGGGCAAAATT +TTCTTGAGTAATATCCCACAAGCAAAGGCAACCAAAGCAAAAATGGACAAAGAAGATCAC +ATCCAGTTAACAAGCTTCTGCAGAGCAAAGGAAATAATCAACAAAGTGAAGAGACAACCC +ACCAAATGGGAGAAAATATTTGAAAACTATCTGTCTGACAAGGAACTAATAACCAGAATA +TTTAAGAAGCTCAAACAACTCTATAGGAAAAAAAGCTATTAATTCAATTTAAAAATGGGC +AAGATTTGAATGGATATTCTCAAAAGAAAACACACAAATGGCAAACAGGCATATGAAAAA +GTGCTCAACATCACTGATCATCACAGAAATGCAAATCAAAACTACAATGAGACATCATCT +CACTCCAGTTAAAATGGTTTGTATCCAAAAGACAGGCAACAACAAATTCTGGCAAGAATG +TGGAGAAAAGGGAATCCTCATAAACCTCTGATGAGAATGCAAATTAATATATCCGCTATG +CAGAAGACTTTGGAGGTTCCTCAAAAAACTAAAAATAGAACTACCATATGATCCAGCAAT +CCCACCGCTGGGTATATACCCAAAAGAAGGGAAAGAAATATATTGAAGAGATATCTGCAC +TCCCATGTTTGTTGCAGCACCTTTCCAATAGCCAAGATTTGGAAGCAACCTAGTTGTCAA +TCAACAGATAAATGGATGAAGAAAATATAGTACTTATACACAGAATACTATTGAGCCATA +AAAGAGAATGAGATTTAGTCATTTGCAACAACATAGATAGAACTGGAGGTTATTCTGTTA +AGTGACATAAGCCAGGCATAGAAAGACAAACATCACATGTTCTCACTTATTTGTGGAATC +TGAAAATCCAAACAATTGAACTCATGGTGATAGAGAATAGAAGGATGGTTAACAGAGGCT +GAGAATTGTGGTGGTGGTAGGGGTGGATTGGGGATCATTAATAGGTGTAAAAAAATTAGG +AAGAATAAATAAGAACTAGTATTTGCTAGCACAGCAAGGGACCATGATTAATAATAATTG +TACATTTTAAAACTAACTAAAAGAGTATGATTGGATTATTTGTAACACAAAGACAGGATA +AATGCTTGAGGGGATGAATACTCAATGTTCCATGATGTGACTATTACACATTGCATGCCT +GTACAAAAATACCTCATGTATTCCATTAATATATCCATCTATGTATCCACAAATATTTTT +GAATCACATTTTCACATAAATACATAAATTTTTATCTATAAATTAAACAGAAATTTATAA +AACATATTAAAAAAATGGCAGTGTTCCAAAAAAAATTCTGTCAGCTAGATAATTATTATT +GAGCAGTATGCCCCTTCACACTGGTCAGCAATACCATCCCATTTACATGCCACAGTCCAA +CATTCGTCTGGGTCTGACCTTGGGCTTTTTTTTTTCTGTCTTATTGTCCACTTTTTCTAC +TACGTAATCAAAAGAACACTGCCTCAGTTGCTGCATTTTATATTAACTTTTACACCAAAT +ACAGTCTCATCTATGTTTTTGTGTACATTTTTAAATGAGCTTTTCAAGTTAGAAAAAAAC +AGTGTTTGCATTCTGATTGGGATATTTCAGACTCTGAGATTTTCAGGAAATTTGACATTA +TTACAGTTAATGAACTTTGTGTCTCTCTCCAGTCAATTTAGGTCATGTTTAATATCTTCA +ACAAGGTTTTATCATTTTCTCCATAAGAACTTTGCCTATCTTCATTATGCATATTTAGAG +ATACTTATGATCATTGATATTGTCATGCAAAGTAGCTTTTTTATTTAATAATGTCCCCAT +GCTTTTAACAGCATTCAGATATACCATTTGGTGTTTCAGTATTTTATTTTGCTGTTCATG +TTTTTATTCTGCTTTAATATAAAATACACTTCAAAGTATACCATTTTAATATGTGACAGA +AAACATTTATTTTAAACATGTTCTCAAAATCACTCAAAATCCTAAAACAGGAGCAACATG +GAGACTCTAGGCTTTTTCTCTGAGTTAATTATGCATTTGCAGGAGATCTTCTCTCATAGA +CCTCTACATTTTTCCCTCCGAATTTGTTTTTTTGGCTTAAGCAATAGAAATCTATTTCTC +ACACTTCTGGAGGCTGGGAAGTCCAAGATCAAAGCGCTGGCCAATTTGCCTGAAGGCCTT +CTTCCTGACTTGCAGAGAGTCAGTCTCCTTCTCCCCATGTTCTCATGTGGCAGAGAGATC +TGTCTCTCTTCCTCTTTTTTTTTTTTTTTTGTGTGTTTTTAGTAGAGATGGGGTTTCACC +GTGTTGGCAAGACTGGTCTAAAACTACTGACCTCCAGTGATCCTCCTGCCTTGGCCTCCC +AAAGTGATTGGATATCTTTCTCTTTTTTTAAAAAAAAAATTTTATTTCCATAGGTTTTTG +GGGAACAGGTGGTATTTCATTACGTAAGTTCTTTAGTGGTGATTTGTGAGATCGTGGTAC +ACTCATCACCTGAATAGTATACATTGAACCCATTTCATAGTCTTTTATCCCTTAGCCGCT +CCCCATGCTTTCCCCTGAGTCCCCAAAGTCCACTGTGTCATTCTTATGCCTTTGCATCCT +TATAGCTTAGCTCCTGCTTACCACTGAGAACATACGATGTTTGGTTTTCCATTCCTGAGT +TACTTCACTTAGGTTAATAGTCTCCAATCCCATCCAGCGTGCTGCAAATTAATTAATTTC +TTTTTATGGCTGAGTAGTATTCGATCATATATCACAGCTTCTTTATCCACTCATTGATTG +ATGGGCATTTGGGTTGGTTCCATGTTTTTGCTATCGCGAATCGTGCTGCTATAACCATGT +GTGTGCAAATATCTTTTTTCTATAATGACTTCTTTTCCTCTGGGTACATACCCAATAGAG +GGATTGCTGGATCAAATGGTAGGTCTACTTTCAGTTCTTTAAGGAATCTACACACTATTT +CCCATAGTGGTTGTACTAGTTTACATTCCCACCAGCAGTGTAGAAGTCTTCTCTTTTCAC +CACATCCATGCCAAAATCTATTATTTTTTTATTATGGCCATTCTTGCAGGAGTAAGGTGG +TATCACATTGTGGTTTTGATTTGCATTTCCCTGATCTTTAGTGATGCTAAGCATTTTTTC +ATATGTTTGTTGGCCATTTGTATATCCTCTTTTGCTTATTGTCTATTCATGTCCTTAGCC +CACTTTTTGATGGGATATTTTTTTCTTGCTAATTTGTTTGAGTACGTTGTAGATTCTGGA +TATCAGTCGTTTGTCAGATGTATAGATTGTGAAGATTTTATCCCACTCTGTGGGTTGTCT +GTTTACTCTGCTGTTTCTTTTGCTGTGTAGAAACTCTTTAGTTTAATTAAGTTCCAGCTA +TTTATATTTGTTTTTATTGCACTTGCTTTTGGGTTCTTCATCATGAAATCCTTGCCTAAG +CCAATGACTAGAAGGATTTTTCTGATGTTATCTTCTAGAATTTTTATAGCTTCATGTCTT +AGATTTAAGTCTTTGATCCATCTTGAGTTGATTTTTATATAAGGTGAGAGATGAGGATCC +AGTTTCATTCTCCTACTTGTTTGCCAATTATCTCAGCACCATTTGTTGAATAGGGTGCCC +TTTCCCCACTTTATGTTTTTGTTTGCTTTGTTGAAGATCAGTTGGCTATAAGTATTTGAC +TTTATTTCTGGGTTATCTATTCTGTTTCATTGGTCTATGTGGCTATTTTTATACTAGTAC +CATGTTGTTTTGGTGACTATGGCCTTATAGCATAGTTTGAAATCAGGTAATGTGATGCTT +CCAGATTTGTTCTTTGTGCTTAGTCTTGTTTTGGCTGTGTGGGCTCTTTTTTGGTTCTAT +ATGAGTTTTAGGATTTTTTTTTCTAGTTCTGTGAAGAATGATGGTGGTATCTTGATGAGA +ATTGCATGGAATTTGTAGACTGCTTTTGGCAGTATGCTTATTTTCACAGTATTGATTCTA +CCCATCTATGAGCATCAGATGTGTTTCCATTTGTTTGTGTCATCTATGATTTCTTTCAGC +AATGTTCTGTAGTTTTCTTTGTAGAGGTCTTTCACCTCCTTGGTTAGATATATTTCTAAG +TATTTTATTTTATTTTATTTTTTGCTGCTATTAGAAAAGGAGTTGAGTTCTTGATTTGAT +TCTCAGCTTGGTTGCTGTTAGTGTAAAGCAGAGCTACTGATTTGCATATATTAATTTTGT +ATCCTGAAACTTTGCTGGATTCATTTATCAGTTCTAGGAGCTTTTTGGAGGAGTCTTTAG +GGTTTACCAGGTATAGAATTATATTATCCGCAAACAGCGACAGTTTGTCTCCCTCTTTAC +CAATCCGATTGGTCTGCCTATGACTTCCAGTACTTCACTGAATAGAACTGGTGACAGTGG +GCATGTCTTGTTCCAGTTCTCAAAGGGAATGCTTTCAACTTTTCCCCATTCAGTATTATG +TTGGCTGTGGGTTCGCCATAGATGGCTTTTATTGCCTTGAGGTATGTCTCTTGTATTCCA +ATTTTACTGAGAGTTTTCATCATAAATGGATGCTGGATTTTGTTGAATGTTTTTTCTGTG +TCTATTGAGATGATCATGTGATTTTTGTTTTTAATTGTGTTTATGTGGTGTATCACATTT +ATTGACTTGGATATGTTAAACTACCCCTGCATCCCTGGTATGAAACCCACTTGATCATAG +TGGATTATTTTTTTTTGATACGTTGTTAGATTTGGTTAGCTAGCATTTTGTTAAGGAATT +TTTCACCTATGTTCATCAGGGATATTGGTCTGTAGTTTTCATTTTTGGTTATGTCCTTTC +CTGGTTTTGGTATTAGGGTGATACTGGCTTCATAGAATGACTTAGGGAGGATCCCCTCTT +TCTCTATCTTGTGTAATAGTGTCAATAAGATTGGTACCAATTCTTCTTCGAATGTCTGGT +AGAATTCAGCTGTGAATCTGTCTGATCTTGGACTTTTTTTGTTTTTGTTGTTGGTAATCT +TTTAACTACCATTTCAATCTCACCACTTGTTATTGGTCTGTTTAGGGTATCTAATTCTTT +CTGATTTAAGATAGGAAGGTTTTATCTTTCCAGGAATTTATCCATCTCCTCTAGGTTTTC +TAGTTTATGTGCGTAAAGGTGTTCATAGTAGCCTTGAATGATCTTTTATATTTCTATGGT +GTCACATAATATTTTCTGTTTCATTTGTAATTGAGCTGATTTGGATTTTCTCTCTTCTGT +GCTTGGTTAATCTTGCCAATGGTCAATCCTTATTTATCTTTTCAAAGAACCAGCTTTCTG +TTTCATTTATCTTTCGCATTTTTTTGTTTCAATTTCATTAGTCCTGACCTGATCTTGGTT +ATTTCCTTTCTTTTGCTGGGTTTGGGTTTGGTTTGTTCTTGTTTCTCTACTTCCTTGAGG +TGTGACCTTAGATTATCTATTTGTGCTTTTTTATACTTTCTGATGTCGGCATTTAGGGCT +ATAAAATTTCCTCTTAGCACTGCCTTTGCTGTGTCCCAGATATTTTGATAGGTTGTGTCA +CTATTGTCTTTCAGTTCAAAGAATTTTTTAATTGACATCTTGATTTCATTGTTGACCCAA +TGATCATTCAGGAGCAGGTTATTTAATCTACATATATTTGCATGGTTTTGAAGGTTCCTT +TTGGCATTGATTTCCAGTTTTATTCCACTGTGGTCTGAAAGAGTACTTGATATAATTTCA +GTTTTCTTAAATGTATTGAGACTTGTTTTGTGGCCTATCATATAGGCTGTCTTGGAGAAA +ATTCCATGCACTGATGAGTAGAATGTATATTCTGCAGTTGTTGGGTAGAATGCTCTGTAA +ATATCTAGTAAGTCCATTTGTTCCAGGGCATAGTTTAAATCGATTGTTTCTTTGTTGACT +TTCTGTCTTGATGATCGGTCTAGTGCTATCAGTGGAGGATTGGAGTCCCCCACTATTATT +ATGTTGCTGTTCATCTCATTTCTTAGGTCTAGTAGTAATTGTTTTATAAATTTTGGAGCT +CCAGACTTAGGTGCATATATAGTTAGGATTGTGATATTTTCCTGTTGGACAAGGACATTT +ATCATTATATAATGTCCCTCTCAGTCTTTTTTAACTGCTGTTGCTTTATAGTTTATCTGT +TATCATAGAATATCTTTTTCCACCCATTTACCTTAAGTTTATGTGAGTCCTTATGTGTTA +GTTGAGTCTCTTGAAGCAGTGGATAGTTGGTTGATGAATTCTTATCCATTCTGCAATTCT +GTGCCTTTTAAGTGGAGCATTAAGGCCATCTACATTCAATATTGAGCACTGAGATGTTAG +GTACTATTCCATTCATTGTGCTATTTGTTGCCTGTATACCTTGTTTGTTTTTTATTTATT +TTTGTTTTATAGGTCCTGTGAGATTTATGCTTTAAAGAGGTTCTGTTTTGATGTGTTTTC +AGGATTTGTTTCAAGATTTGGATCTCCTTTTAGCAGTTCTTGTAATGCTTGTAATGCAGT +TCTTGTAATGGTCGCGGTGAATTCTCTCAGTATTTCTCCGAAAAAGACTATCTTTCCTTC +ATTTATGAAGCTTAGTTTTGCTGGATACAAAATTCTTGGCTGATAATTGCTTTGTTTAAG +GAGGCTGAAGATAGGGATCCAATCCCTTCTAGATTGTCAGGTTTCTGCTGAAAAATCTGC +TGTTGATCTGATAGGTTTGTCTTTTTTTTTTTTTTTTTTTTTTAGGTTTTATCAAGTTAC +CTGGTGCTTTTGCCTCACAATTCTTAAGATTCTTTCCTTTGTCTTAACTTTAGATAACTT +GGTGAAATGTGCCTAGGTGATTATCTTTTTGCAATGAATTTCCCAGGTGTTCTTTGAGCT +TCTTGAATTTGGAAGTCCAGGTCTCTAGCAAGGCCAAGGAAGTTTTCCTCGAATGTTCCC +TCAAACACGTTTTCCAAACTTTTAGATCTCTCTTCTTCCTCAGGAACACCAATTATTCTT +AGGTTTGGTCATTTAACATAATCCCAAACTTCCCTGATACTTTGCTCATTTTTTCTTATT +TTTTTTATTTGTCTTTGTCAGATTGGGTTAATTTAAAAACCTTGTCTTCGAGCTCTAAAG +TTCTTTCTTCTGCATGTTCAATTCTATTGCTGAGACTTTCCAGAACACTTTGCATTTCTC +TAAGTGCATCCATCATTTCCTGAAATTTTGATTGTTTTTATTTATGCTACCTATTTCACT +GAAGATTTCTCCCCTCATTTCTTGTATCATTTTTTTGATTTCCTTAACTTGGACATCATC +TTTCTTTGTGCCTTCTTGATTAGCTTAATAACTGACCTTCTGAATTATTTTTCAGGTAAA +TCAAAGATTTCTTTTTAGTTTGGATCCATTGCTGGTGAGCTAGTGTGATTTTTTGGGTGT +GTCAAAGAACTGTATTTTGTCATATTACCAGAATTCTTTTTCTGGTTCCTTCTCATTTGG +GTAGGCTATGCCAGAGGGAAGGTCTACGGCTTAAGGCTGCTATTTGGATTCTCTTGTCCC +ATAGGGTGTTCCCTTGATGTAGTACTCGCACCCTTTTCCTAAGGATGTGGCTTCTTGAGA +GTGGAGCTGTAGAGATTGTTATCTCTTTTCTGGATCTAGCCACCCAATAGGTCTACCAGG +CTCTAGGCTGGTACTGGGGGTTGTCTGTACAGTCCTGTGATGTGAACCATCTCCAGGTCT +CTCAGCCCAGGATACCAGCACCTGCTCTGGCGTAGGTTGCAAGGGGGTGAATTGTACTCT +GTGAGGGTCCTTAGTTTTGGTTGTTTAATGCACTATTTTTGTGCTGGTTGGCCTCCTGCC +AGGAGGTGGCGCTTTCAAGAGCCATCTGTTGTGGTAGTGTAGGGATGATCAGGCAGTGTG +TTGGGGCCCTAGAACTCCAAAGAGTATATGCCCTTTGTCTTCAGCCACCAGGGTGGGTAG +GGAAGGACCCTCAGATGGAGGCAGGGCTAGGCATGTCTGAACTCAGACTCTCCTTGGGTG +GGTCTTTTTTGCTGCAGCTGCTGTGGGGATGAGGATGTGGTTCCCAGCTCAATGGACTTA +TGATCCCAGGAGGATTGTGGCTGCCTTTGCCATGTCATGCAGGTTGTCAGGGAAGTGGGG +GAAAGCCAGAAGTCACAGGCTTCATCCAGCTTCCACACAACCCCAGAGGCCAGCCTCACT +CCCACCATGCCCCCACCAAGAGGGCTGAGTCTGTTTCCAGGCAGTGGGTGAGCAGGGCTG +AGGATTTCACCAGCCTCCCAGCTGTGAAAGGAAGCAGGCCTTTTGTGCCTCCCTGCGTGT +GGAGTCAGCACACCAGATTCACCCCCTCCCCGAGTTCTGGCCAGGAGACTTAGCATTCAG +TTGGAATTGTTACAAAGTTCAGTTCGGTTGGAGGTGTCCTTCTCCCTGTGGTCTTTTCCC +CATACCTCTGGCAGCCATCCCCAAGGACCCCTATAAGGCAAGGCAGAAATGACTTCCCAG +AGGACCCAGAGAGCCCACAGGGCTTTTCCTGCTGCTTCCTCTACCTCTTGATTTCTTAAG +TATTTTTTTGTTATTCCTATTTTAAGCAGTATTTTTCTTTTAATAGCTTGAGTAGAAATG +AATTTGATTGCTTTGTATCAACCTTACAGTCAGTAAATTTGCTATTTGAATAATTTTAGT +AATTTGTAAGTCTTATGGCATTTGTCTTTGAAATGTCCTCACATCTGTCCCATCCTTCTG +CCTAACTAGCTTGCACACTACCTGGTACTCCCTTTCACTAGGCCCTCATTCACATCAGCC +CTGCATTTCCAGAAGAGCTTCTCAAATCTATTCATTGTCTAGTAATTTACCAAACTCTAA +TTTAGTCTTAAAGAGCATTTCTTAGTGAATGGAAATGGGCCTGGTTCCTAGATAAAAATA +AAAGTGTTCAAAATCTAAGATCCGTATCTTATTCGATTTTCCTGCCTTTCATTTAAATTC +CTCTAAAAAAATTTCATACTATATATTTATAATCTCAATTTCCAACCTGCTATCTTCCAT +TGCTGTCCAACAACCATCCTTTGCTATCTTCCTCCCTTTACTCCAACCTGCTACATATCT +CTCTAAATATTTCTGTTGTAAGCATTAGTCTCTGCTTTCTAAAGTTTTTCTTATTACCCA +TATCAAAAACTCCTCTCACCCTCAAAACAGTAGTTAAGCCCCTCTTCTATTTGAAGATCT +TCTGTGTTCCAATCCACTTTGATAGCTCACTGCCCTTAGTAATTACTCTTTGCATTTTTA +TATTGTTAGATTGGTTTTTTTTATGTTTTTACTTTTCATCTGTCAATGATAATTTACTGA +ATGTCTCACATGTGTCAGGCACTGTGTCCCGCAGCAAAGCCTCTTTCATAGGTTGCAAAT +ATGTCACTAAGTATCTCAAAAATAGCCTAAAGTTAACCTCAGCAATTATAGCTGTTCAAT +CAATATCTCTTTATTAATTTCCCTTTTTACACAATTTCTTTCAGAGCAATTCTGCACATG +ATAAACATTTAATGTACATATTTGTTTAATACAAATTAATGAATACATTTTATTAAGAAA +ATAAGACATTCTCCTGAAGGCAAAGCGAGTTGTATTTTTTCCAATGTAACTTGGGAAGTT +CTGGTGGCTATGACAGGATTTCTTTGGGGAAAAAAAAGTATATGATGTGCTGCAAATTCC +AGAATCCTGATATATATTTTCCCTGGTTTGCCTAATTTCTATTAAAATAAACTGTCTTAT +TCCAAATCAACTTAACATAATTTAGGATAAATCACTGTAACTTTGTTTGATGTTAGCATT +AAGTGGCCTATGTTATCACTTCATTATAAGGTATCTTGTGGATTTCTCTCTCCAAGTTTT +ATCAAGAAGGAGGATATAAGCCTGCGATTGTCAAACACCTTGTCTGTAAAAGAATTTTTT +AATTTTGCATTTTACAGAGAACCATTTAGAAAGTACAAGTTCTACAACCCAACTATTTAC +TCAAGAAACAATTAATTAGCTTTCAATGACCTTCATTAATGATCGTAGTATTTCTAATTT +CACCTACTGTTTAACCTTTTGAATTTCAGTCAAGACAAACAGCTCCACATGATACAACAC +TTAATCAGAATGAATGCCTCAAATGGAAAAAGACTTTTGTAATCTCAAGTATTAACATTA +ATAATACAATTGAATGACAAATATTTGCACAAATAAAGGAACAATAATCTATATTTTCTG +TCCATTTTATTTCTGGGAAGTAGTGGATGCCAAGAATGTATGATTCTAATTATAGATTCC +ATCATTCCAGAAAATATGGATATAGATAATTAAGCTCCATAGAAATACTCTTACATGTAT +TGAAAACTTATAAATAATTAGTTTATACTCTCTTAATAGCTTCCTATGAGCTACATTTAT +TTCTATAGTAATGGCTATGATATTTCATCATATTTTTAGCCAGTGATATAATTTCTTTTA +CTATGACAATAGTGAATTTTTTCTGCCATTATCCCTGCACATTTTAAAAACCTTTCTAAA +ACCGATATGAAAGCTTCAATAAAGCCTTTTTTTTCCCTTTATTTTATATTTTCCAGAAAG +GTAAATAATGACTTTCAAATAATTTTTAAAAATTCTTTTTAAGGTTTCTTTTAAAATTTA +AAAGGATTTCCTTTTTCCTTTTTAGTTTTTTTGTTTTAAAGACTCATTTAAAATGACTTT +ATAATATCACCACAGGGACAATAATGCTAAAATAACAGAGCTAGACTCTTCTTCTTCCAC +TTTGTGAATAATGGAGGGATCAAAGTCATTCATACCCAGATTTCCTTTCCTAAGCTATAC +AACGTTACAAAACAAACTAAACACTGAGATTACTTGTCTTATTATCTTATTTAAGTAAAA +GGCTATTACTCATTGTGACTAGAATTGTAACAATTAGACTTATTCTCTGAATGCATTAAA +ATAAATTTCTATAATTAAAACAAGTATACTATTTCTATAGCAAATGTGGAAAGTATGCCT +CTATCTTCACTTAAATTCAGAATAATTTTAGTAACCCCTATTTAAATAAATGCAGGTTAA +TAAATCAAAATACCATTAACTGGGTAGCTTGTAAACAACAGAAATTCTTTTGTTACAGTT +CTAGACACTGAGAAGTTCAAGATCAAAATACTAGCAGATTCAGTGTCTGGCAAGGACTCA +GTTTCTTATAGATAGCCCCTTCTCACTGAGTTCTCACATGGGGGAAGAGGCAAAGCAGAT +CCCTGGGGACACTTTGGGCAACTAATCCCCTTCATGAGGGGTTTACCCAAAAACCTTACT +TCTGATTACCTTTCAAAGACTTCACCTTCCCATTACAAAGATGCTGGGGATTAGGATCCT +CATATAAATTTAGGGGGGATATAAACTTTCAAATCGTATCAACCCTATCCTTGCTTTTTT +AGCACTTCAGAAAGCAGTAATATTAAGGCACATTTTCCATAGGTGCAGAATCTCCATTAT +ATGATTATATATATGTGTGTGTGTACATATATATATTTACATTTACTTCTGTCAAAGTTT +TTTTTTAATACTTTAAGTTTTAGGGTACATGTGCACCATGTGCAGGTTTGTTACATATGT +ATACATGCGCCATGTTGGTGTGCTGCACCCATTAACGCGTCATTTACATTAGGCATATCT +CCTAATGCTATCCCTCCCCGCTCCCCCCACCCCACAACAGGCCCCGGTGTGTGATGTTCC +CCTTCCTGTGAACAATGAGTACACATGGACACACGATAAAGCCTTTTTGAGAAATGCTGA +CAGAAACAAAGTTAGAACAAATGTGAAACAAAAAGTTTCATCAGAGATTTTAGTATCTTA +ACATGCCTTACAAAAGTTCGGGAGGGGCAATAATATGTATGAAACTTCCTAAAAATCTTT +AACCATGGAACCCTTCTTTTTTCAACTTTCCCATAGGACTGAAGACATGTTTTGAAATAC +ATTGGTAGAGTGAAAATGATTCATTAAGATTACATTTGAATCCCAATTTCTCTCAGTTCT +GCCTCTGTTCGTTTTTGTGTTTTTTTTTTTTTTTTGCCTTGATATCATCATATGTAAGCA +GGAAGTATTATTGACCTAATGGGGCATTGTATAAATGCAATAAGCGATTTCAATTGACTT +AATTCAACAAACGTTTACCTAGGTTCTAGTAAATGATCAGTATTTAGTTAGGAGCTGGAG +ATAAAGAAACTAATAAAACATAACCCCTGACCTCAAAGAGTTATTGTTTTAAAATTCATC +GGCCATTTGCTGCCGTGGGAATTTTCTCTGGCCACATTCTTCTTTGGTTCCCATTTACTA +CACGTTTTCTTTGCATTTTTCACTCTTCTCTGGCCGTCAGCTGCAGACTGTTATAGTCCT +AACCAGAGTAATTTAACCTTCCATTTCCCCAAACCAGCTATCCTTGAAAGTCCAAAAACT +CATAGATGGCAAACAATAAGCCATATATGCTGGATATCTGTCCTTACAAATACAAAAACA +ATAAAATGATTGAAATGAAAGATTTTTCTTGAACACACACCAGATCAAATTCTTAACACT +TCTCTCATCCAGACGTCTCATTCACGAGAGAAACAACGGAAACATATAGTGTCCTGAGGG +CTCTGTGGTCATCAAGAAAGGTGATTGTTATTATTATTAATTGTGTACACTTTCATTTAT +TCTTATACAAAATGAAATCTTCAACCAAATACTACACATACAGAGGTTAGACCTCTTATC +TCTAATAATCAGCATTTGTTGCCATCACTATTGGGAGTACACTCAATTGAAGAAAGGAAA +GAAAGGTAGGCATATAACCGTGAATGAACAAAACAAACATGTTCTTATGAACATTGAATG +TTTCTGGCTGAGTGCAATGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGTCAAGGCAG +GTGGCTCATTTAAGGTCAGTAGTTCGAGACCAGCAAGGCCCACATAGTGAAATCCCGTCT +CTACTAAAAATACAAAAATTAGCTGGGTGGTAGTAGCACACACCTGTAATCCCAGCTACT +CGGGAGGCTGAGGCAGGAGAATCGCTTGAGCCTGGGAGATGGAGGTTGCAGTGAGCTGAG +TTCACACCACTGCACTCCAGCGAGGGTGACAGAGAGAGACCCTATCTCAAAAAACAAAAC +AAAGCAAAACAAAAAATAACAAAAAATTAAATGTTTCTCAGCTAACCAAATTAGAATGTC +TTCAGCTGAAGAAATAATAATTTATTCCAATTCAAAATAAATTTTTGACTACTACATCAA +AAAAGAGGCAGTTAAAAATATACAAAAATGAAAACACAACCTCAATTTAAATTTTGCTGA +AGCAATAATCTCAACTTTTAAAATACAAGCTTAAATTTTATACTGATAAATAGTTAACTA +TTTATTGAAGCAATGCTCTCTGTTTAGAATTGTCAAATGATTTTTCTATTTTGTTTGCTT +TGTATTTGAGAAAAAACCTTAGATTAGAAGCTTGAAGGTACAGATTACAATCTGCAGAAT +GTAAACAGAGTAAATTCTGCAAAAAACAGCTCAAAGTAGAATGCCAGATTCTCTGGAGCA +CTTGGAAAATTCTGACTACCTCAAGTAATTCCAGAGGATTCTTCCTTACTAAGTTCACTT +GAATTTTTCATAGAAGACATTCATCTACCTGGTCAGAACACGAGCCCATAATTTCTGAAA +AAGCATTATTAGTGTTTTGTAGATATCCAGAAATATTCATATTTACAAATATTTACAAAT +ATCCAGAAATATGAATATTTCTGGATATCTACTCTCTCTTGCTTCACACACCCAATGTTG +TGTTATTCTGTTTTGTGATTCCAGAATGAGATTAGATAATCTAATCAGGCATCATGTAAA +AATTAAAGATTAATAGGGTCCCCTTTTCTTCCAACCTTATATCTTGGTGTAATGCTGATT +GCCTCTTGATATGCTTGGCTGTGTGTCCCCATCCAGATCTCATCTTGAACTGGAATCCCC +ACATGTCAAGGGAGGGAGGTGATTGAATCATGGGTGTTGTTTTCCCCATGCTGTCCTTGT +GATAGTGAGTGAGTTCCCATAAGGTCTGCTGGTTTTCTAAGTGTTTGGCAGTTCCTCCTT +CACATGCTCACACTATCTCTTGCTGCCTTGTGAAGAAGGTGCCTGGTTCGCCTTCCACCA +TGATTGTAAGTTTCCTGAGGCTTCCCCAGCCATGTGGAACTGTGAGTCAATTGAATCTCC +TTTGTTTATAAATTACCCGGTCTCAGATAATGTCTTCATAGCAGTGAGAAAATGGGCTAA +TATACCTCTTATTAACATACATAATATACCTCTTATTAACATACATAAGATAATATACCT +CTTATTAATATACATAAGACAACCTCTTATCTACATAAGATACTACTGACAAATAAGACA +GTTTTCAGGGTTTATCTTTCTTTGATAGAGAGGAGAGTTTAGAAAAGTAAATGTAATAAA +GATCATGGGTAAACACATTCTGATATGTTACATAGGTATGATGTAGAGTTACCAGAACAG +TTCACAAATATTATCAAATACTTTTCTTGATTATTTTTTGTGCCCAAGAAAACATCATAG +TCATTTTCTTTAAAATTACTTTATCTTCTTCTAGGGAACCTTTTATTTTTTTTAACTGTA +CAATCACCAAAATAAAATTTCTAGATTTAGGTTCTTACTGATGAGATTAGTAAAATGGCT +AAAGCTTTACGTACATTTACCCTAAGAGGGTACTATATCTTTTTCCAAAGAAAGAGGACC +TGCCTGCCTAATAATTATACCCATGTTTCAGAGGCAGCTAAACAGAAGAAGGAAATGAGT +GTTCCATCCCTGCACCCTCCCTCAGGGCAGTGAGAGAGTCGAAGGTCAGTTTTCTTCTTG +ATGGTCCCTTCTCAAAACTTGCCTTGAACTTTGAATTATGACGTGTGTTAACTATCACTT +CTGCCTCCAAAGTACTTCAGGTCAGTAGTCTGTTAAGATACTGCTTGCTATTAGACTATG +AATTTAAACATAACAATACATTCCACAAATGATAATATTCTGTCACTTTTGTATACCCTT +TATGTGCTTATCAACAATTGTAAAAACTGAACACATAATGCATATATCTAGTTCTTCATC +TTTTTTGGGGGGAGTGAAGTCTTTTCAGCACACATAGATGAAAAATGACGTAAGGGAAAA +CTCCACTCACTTCTTTTGTGTATGCAGGATCCAAAAGTAAACTATAATCCCCATTCCAGG +CTGCAGTGTATATTTTACTCATGTGTCTAGATAAGTGCACTGTATATGTTATCCCATATA +ACACAGAAAATATATCACTGCAAAGCTTTAAAAAGTCATTCTGTCATTTTGAATCAAAAG +TTGGGGGAGCAGATGGGTAACTAGCTTGGAGGAGAGAGACGGGGTTACTATTGGCCAAAT +GCAAGAGGAAGTATGAGAGTCTAATGATGAGGGCATTCTACTGCTAAGCATGTACAAAAT +TTAGTTTTGGTAATAACTTTTCTACTCGGCGTGCATTTTATAGCTTGGGGTTATCTGCTG +ACAATGTAAGAATTGAACATCAAGTGGAAGCTCTAAGGAATCAGAGTGGATATTTTGAAA +GTTGCTAACAGAAGTAAATATAATTTTGAGTAAGAACATAGGTGTTTATCCAGCACAGAG +AGCGCATGATGTGTTGGATTGGAAGTTACCCTCTGTATTATCAAGGCTGTCCTCAGTAGT +TTCTATCTGTACAGTGTTTGACATCAAGATTACCATGTGTTCTTCACAGCCAGCTAGTGA +GTAGGTTAATAATTTTTGTGCTGTTGTATAAATGGTCCAACTGAAACAGATAGGTTCTAC +AAACCTTGGAACAAATACAGAATGGAGTGTGTTATTTAAAATATGTCAAAAGCTATATGA +GAAGCTATATTATTATAAGTATATAAAGTACCAAATAAGGTTAAGTAGATATCCTCTTAA +TTTTGAGGTTCCGTTTAATCAAGATGGAAATTCAATCAGTAATAGAATGTCGGCGTTTAA +GATTTTTTTTTTGGATTAATTTAACTAAAGTAGTTGTGTAAGCTCCATAAATTAAATTTA +TGATGATGTGGGTCAAATGAAAATATGTGACTTTACGGTAAAGCTGTAATCATAAAAAGG +TGAACATTGCCTATGTTGTCTTCCAACTGAAATAAATTGGTTACCTAAAAATCTCTTCCC +AATCCTTCTGACTTCAGCTCAGTCATATAAGAGCTCAGAAAGCAACAACTCCATTTTTAC +AATAAGAAAAAAAAGATTAACTTAAAAAATCAATGACTTTTTAAGACTCATCTGAGAATT +AAGGTCACATGGCAAACTGCTACCCCAAATTCTGTAGACAAATGAATGTAGACAATCACA +GCACAGAGCAACTGACTTGGAGCAGAAACCACTGCACCCAGACACTGGCAGGAACACTCG +CCTTGTAATTTTGATATTTATTTCCTGAGGCTGAGTGTGGATTAGATTGAGAAAGAAAAA +CCCTGGATGGTTTCCATCTTATGGGGACCCCACACTTTTATAAATTTTACCTCCAGGAAT +TCTACAATATTCTCATGGTAAAGAGTTAAAAAAAAAAAAAATCCCTTCTTGGCTCTGGCA +GGAGGAGGTGAAAGTGGCCATCTGGAAATACACATTCCATAATGAAGGCCTGCTCTCCAG +AGGAAGGGCTATTACCCAACTCCAGGCCACTCTAGAGTCACCTAGTGTGAGAAAATCAGG +GAGAAAAGTGTTAAATATACTTGTAAAGGTCATACACCAGGCCCGAAGCCTACTAAAAGA +CAGATTTAATCCTAAAATTACTTAACACTTAAAGCTCCTTCACCTCATCCTTTCCTTACC +ACTACACCAACTAGCTCCAGTCTGATACCAGTGGATACAGATGAAAGAACTGTAAGACAC +AGACTCCAAGAAGTTCTTGGGGGAAACTCAAAGACAACAGGAGAGACAAAAACAAGGACA +CTAGAGGAATTTGCAGATCCTAGAACCTACAGCTATTGGAAATACTATGCATAGCCAAGC +TCCTACCCCAACAAACTTAAAAACTCACATTGAAAGCCTATTTTACCCTATTCCTGTAAC +TCAGTATGTCACGTCCAACTTCCAAAAAAATTACAAGGATAGGCTAACAGGGAAGAGAAA +ACACAATCTGATGAGACAAAGCAAACCTCAGAATCAGACTCAAATATAATACCAAATTTG +GAATTATCGAATAAGGATTTAAGAGAACTATAATTAATATAATAAAAATTCTAATAGAAA +AAGCAGAACAAATGGATAATATAAGCAGAAAGAATGAAACATTAAGAAAGAATCAAAAGG +AAATGCTGGAAATACAAAACACAGTTACAAATGAAGAATGTCTTTGGATGGACCTATCAG +GAAAATACGTGAGCTTGAAGCAATGTCAACAAAAATTTCACAAGCTGAAATAGAAAGAGA +AAAACATAATGAATCAATAGAGGATCCAAGAACTGCGAGACAATTTCCAAAGGTCTAATA +TACCTTTAGAAATTGGAATACCAGAGGGAAAAGAAAGAATAGAGCACAAGGAATATTTGA +AGTAATAATGGCTGAAAACTTTCAAAAGTTAATGACATACACTAATTCACAGACTCAGGA +AGTTCAGACAACACCACACAGAATAATTCCCCCCCAAAAATCTACAATTAGGCATGCCAT +ATCCTACTGTGGAAGCCCAACATTGTATTCATTGTATTTCATTTGAAATACAATGAAAAA +AAGAGAGAAAAAAATGCCTTACTAACAAAGAAAAGAGATGAGAAATATTGTCTACTCATG +AGAAACCACGCAAACAAGGAGCTAATTTAAAAAAAAAACAAACAAACCTAGAATTCTAAA +ACCAGCAAAATTATCCTTCAAAAGTGAAAGAGAAATACCTCTTGGAAAAACAAAAAGTAA +GAAATTCATTGTAAGCAAACCAGCCCTGTAAGATGTTAAAGAAGTTCTGCAAGAAGGAAA +GTGATATGGGTCATAAGCTTAGATCTACACAAATAAAGAAAAATATTTAGGAAAAGAATT +ACGGAAGGTAAATAATTTACTTTTTAAATTATCATTTGATATAGTAGATAACTGTTCAAA +GTAATCATGGTACTAATGCATTATGTAATTATAGTATGTGATAAGTGAAATGACTCCTAA +GAATAACATAAGAAATAGAGGGAAGAATTGAAAATACTATGTTTTAAGTTATCTGTACAA +CCCATGAAGTGGTATAGTGGTATTTGAATGTGAAGTTGGATTAGTTAATAGTATACTGCA +AGATGTAGGGCAAAATACAATAAAATAATACGCAAAGAGAAGAGAGAAAATAGAATCATA +AAGTGCTCATACAGATACCCTTTGGAAGACAGTTTTTCAATTTCTAATAAAATTAAACAT +AATCTTACCATGTAAGCCAACAATTGCACTCTGATATTTTATGAAAACTTAAGGCTTTAG +AAAAACCTGCACACAGATGTTTATATAGAACGTTTATTTATAAATTACCAAGACTTGGAA +GCAACCAAGATGTCCTTCAGTAGGTGAATGGATAAAAAATGAAGTACATGCAGACAATGA +AATATTATTCAGCATTAAAATGAAATGAGCTATCAAGCCATGCAAAGACACAGAAGAAAT +GTAAAGGCATAAATCTAAGTGAAAGAAGCCATTTTGAAAAATCTACATACTACATGATTC +CACCTATATGACATTCTGGAAAAAAAGTGGTTCCCAAGGGTGAAAGGGGAGGGAAGGATG +AATAGGCAGAGCACAGAGGATTTTTAGGTCAGTGAAACTACTCTGTATGATACTGCAATG +GTGGATACATGTAATTACACATTTATGCAAAGAATGTTCAAACCCAGAAATTAACTCTAC +TGTAAACTATGGAATTCAGATGATAATGATGTATCAATGTAGGCTGATCAATTGTAACAA +ATTTACCACACTGATGGGGTTGATAATGGGGTAGGCTTTGCATCTGGGCACATGGGGTAT +ATGAGAAACATCTGTGCCTGCCTCTCAATTTTGCTGTGAACATATATCCACTCTACAAAC +AGGCTTAAACCTGCTCAATTGTGAAAGAAACAAAGAATAACAAATAGAAAAGAAAACATG +GTACACACTTGCACATATACACACACATACACACACACATTATACATATATGATGTGCAC +ATGATATAAACAAATACTAAATAGACTGAATATACAACCATTCCTCAATATCCATGGGCA +TTGCTTCCAGAACCCTCTTGCAGATACTAAATTTTGCAGATATTCAAGTCTCTCATATAA +AATTATGTAGTATTTGCATATAACCTAGGAACATCCTCCTGTATACTTTAAAACATCTCT +AGATCATTTATAGTATCTAATACAATGCAAATGCTATGTAAATAGTTGTTATATTGTATT +TTTTAATTTGTATTATGTTTTACTTCTGTATTTTTTTCCCGAATATTTTCTATCCATGGT +TGGTTGAATCTGCTGATGCAGTCCCTGGGGAAAGAGAAGGCTGACTGTATAAATAAATAG +GGGAGAAGAGACAAATTTCCATTGCAGACAAATTCTGCACAATTTATGCATATACGCTGC +ATAAATCTGCACTTTTAAAATGTGGGCTGTAGATAATGACTTTGCTCCACAAAAGTCTCT +ATAGAAAAGGGAGGCAAAAAAGATTACAGTGGAGAAAACTGATAAACACAACTTTAGCCA +GGTGGCCAAGGTCAACGTCAAGAGTGATAAGTCATGCTAACAGTATGTATCTTGATTTGT +TGTTGGGGAAGCAGCCATCACCACCTGTCCCACTCTAGGAGTTTGCTGAATCGAGGCTCT +GGGTCTGGAAAGTTCCCCAGTATGGAAGTTGGCCCCAGATTCTTCTTACTTATTAGGATA +AACTTTCCCTTCTTGTATGTGGTGAACTTCTTTGTGTTGCTTAAGCACGTGCACCAGATG +GTACCTGCCCAGCCCCACCAGTATATCTGCACCCCCAGGGAAGGGAGAGAGTCTCTTGAC +TATGGCATAAGAAGGGTTCATTCTGTCCATCACTCTGCATCAGCTCCTGGTAGGGACCCA +CTTGCCCTGGAAGACTGAGCCCACTACAGATGTTGATCTTGCTGCAGCTCTTCTCATTTT +TGTGAGTACAGAGTTGTTCTAACCAGTGCCTGGTATGTCAAGTCCTCCTTGGCAACTCCT +CATCCTTAGAATATGCAGTGGGCTGAGGTCTGGGGCCTCCTACTGCTGGTGGTTGGCATT +GCTATGATCTTTGCTGCCCTCCATGTGGTGGGGACTCTTCCCTCAAATTGGTTGCTGAAT +CTTCCTGTTTGGTAGTAGGATATGATTGACTTGGCACTTTATCTTTGTGATCTTCCTCAT +AAAAACCAATTACTCTAGTTGAATTATGAGAAAAATATCAGGCTAATTCCAAGACAAGGG +CATCCTATAAAGTAGTTGACTGGTATTTCTCAAAACTGTCAAGGTCATGGAAAGCATGGA +AAGTTTGAGGAACTATTCCAGCCAAAAGGAATCTAAGATGATATGACTATTAAACGTAAT +GTGATAACCAGGATGGGGTCCTGGCATGGAAAACGACGTTAGGTAAAGCTAAAAAAACTG +GAACAAACTATGGATTTTAGTTAACTATAATGTATCAATATTGGTTCATTAATGGTAACA +AATGTACCATAGCAATATAAGATGTTAATTATGTGAGCAGGTATGAGGAAACTCTATGTA +CTATCTTTTCAATTTTTTTCACAAATCTAAAACTATCTTGAAAAATAAAGTCTATTATTT +TAAAATATTTTTGTTATATGGTAGCAGTTGGATACAATGTTTTCACTGAAGCTCTGAAAG +AATATATGCCTGTATTCCCTTTTGAAGGCATATAGGCAACAATGTTTTAATATTATTTTC +GTGTCATTAGTATTTATAGTATAGATAGCTAAACGAACATAAAAGTGAGTTTATTTAAGA +AATGAAAAAATGACTGCTTCTCATATTTTGACCAGTGGCCAAATATGTCTATCTGGAGAT +TACTCCTAGAACAGCTCACGTGTGAACCTAGGAGCTAGTCTCGAACCTGAGTGAGAAAGA +AAGCCTGTGTGTTAGCTTAAAAGTGTGGATCTTGGTGTTCTTCAAAGCACAGTCCATGAG +AGCTGAGAGCCCTGACTTAGAGGAATTCACTCTGGAAAGAAAATGGGGAAGACACAAAGC +ACAGCACTTTCATGTGAAAGTGGACGTGAAGCTGATGAAACTGTTCCCGGGACTGAATCT +GGCTTTCTGCACAGCAGAAGCAATGACTGCCTATGTGTGAAATGACACGCTGGAGCCCTT +GCTAGGATAGAAAGGGCTTAAGGAATCCCTCTTTAATGTTCTGCTTATGAAATTTGAGGA +GACAAATTTTTCCTTAACAGGAATAACTTTTAAAAGATGAAAGAAAGCATAAAATAGATG +CTCTGAGCTAAGGCAGAACGATCAAATGCAGCATCTGGGAAACTTGGTGGTGAGCAGTGT +GTGTCTGAGAGGAGGAAGGGAAATGCTGAGTCTCTGTGGATTGTATTAAGAGTACAAAAC +TCCTTAACACACAGAGGGTGAATCCCCCCGTAAAATATGTCGTAGATACCAACCAGGTAG +GAGCAATGCCTCTTGGGGAGGTGGGGTACAGATGCCACACTTTAAAACTGGACTATCTTC +TGTACTGCGTGTACATCAGAGATGACTAAGCTACTAGGTGTGAGGTCACACAAATACTGC +TGTGGAGGATCTATGCTACGCCCAGAAGAAGGAGAGGTAACTGAAGGCCCTGGGGACAGA +GATGGTGTTTTAAATTTTTATTCCATCAGGAGGTTGAGAGTCAGAAAAGAAAGAAGTATT +TGGAAAGAGAAGAGCAATGTGTACAGGACTTGTGAAAGAACAGGAAGTGGTTTGCAGTGT +GAGGACTGCCTTGGAAGGGCATGGGCACTTTTTCATGTCCAGCCTCTTCTGTCCTGCCCT +TTATCCTCACTTCTAGTGTAGCTGTGAAATGGTACGTGCTCACAAAAGCCTGTGCATTTG +TCGGTCATTGCACTTGCAGCTGACATTGTCACTGTGTAGTAGACTGTATTAAGGGATGGA +GATGGCTGTTGTACTCCCCGACTTGACTTACAAGGAGTTCTCTGCTTACGCATTTATGAA +GGATGAACTTATGAACAGGAGAAGTCAGTCTGGAAAGGGAAGGATTAGACTGAATGAAAA +TCCCAGGAAGATGGAAGTTTCCATCTGTAACTTCAGCATCTAGTATCATGCCTGACATAG +AGCACAGTCTCAGTAGATTTGTATTTAATTAATCATTTACTTAATTAGTTACTGTGAACT +ACAGTGTACATTTAGAAAAGAGAAAAATCATTGTAGTCAAGGGAGGATGGATTTGAATTC +TAGATCTTCCACGTCTTAGTACTGTGACTTACGGGAAGTTTTTAGAAACTTGCTTTCTAC +ATGTACAAAAGAACAATATTCATATTTATTTCACAATGTTGTAAAGAGAATTACATAATG +TAGAAATAGATAGACAGACACATACCATTCTTTAAAAGGCCAGTTAGAGCAGGTACAGAT +ATTAGAATTGTAGTTATGATTGCTTTTATTATTATTTCATGGCTTTTTCCCACATTGGCA +TAGGTTATATGTCATCAAGGGCAGAGAAAATATCTTTTTCCCTCTTTTGTGTTCCTTGGT +ATAACGTAGCCAAGTATGCATTTATTTCTATTTATCTAAATCTGTGTAACTGTGAGCAAA +ATTAATTTTACTACAATGTAAATTTGATAGTGAAAATATACAAAAATATTATAATTCCAC +ATTATAAAAATATTATAATTCCACAATATAAAATATTATAATTCCACAAAGTATGTAGAT +GTCACCCAATGATAAAGATAGGACACATATCAATATACAGCTACCCCACCTTAGGACTCA +TAACCAGTTTACCTATACATTTCAGAGTTAATTCACTGCACTTGCTAACCCACTGAAATT +TCATAGGAGCATGCAACCACAAAGTCATCACAATTCAGTCATTTTCCAGCTATCACTTTG +AAGACTTTCATTTATCACAGTTTTGGGAAATAAGATTTTCAGTTTCTCTGACTTCCTCAA +TAAATAATGTGACCATTTAATAAATATGTGTTTCTTTAGTAAGCAGGCTCTGCCCATGTT +GAAGAAAGTCTTTTGGGATCATTTATTCCTACACACCGGGGAGGGCTGGCACTACATACC +AATTTAATGCCAGTATTCTCTTTCCATGACTACAAATAATAAAAATAGCCTTTTGCTTTT +AAAGTTTGTTCTCCAATAAAATATGTAAAAAATAGAAACAAATGTCTTATTAGTTTCATG +TAGGTATTGTTTTACTATTTATTATTGTGCTTGCATTTCAAGAAAAAGTCAAAGATACAA +AGGTATAAAGAAAAACCAGAATGTTTCTCTCTATCTCTCTCTCCCTCATAGCATCCTTTT +GAATGTTTATTACCAATTCTGAGAAAAATAAACCTCAAAGAATACCTAGCCCTTTCTTTA +CCATTGCTTTCTCTCAAATTCACACACACACACACACACACACACACACACACACACACA +CACGGGCTCCTTGTCAATGAGGCTGGCTGATAACAAAGGAAGACATGGTGACTTTGCTTA +GTGCTTGCATGAAAACATCCTTCCTTTCTGCCCACCCTGCCACTCACCGTCAAGCTACAA +GAAAAGCTATGGGCCTCAAAATCTTTGGTTAGTGCTAGGCGAAAGGCAGAAGAGGAAGAT +AGATGCTAACGTTTTGAAGTGACTAGATAGAATTCAGATAAACCAAAAGGAAAATATTAA +CATTTTGAAGAAAGAAAAATCAGTTTTTATCTTTACACAGAAAAGTTGGGTGGAATTTTT +CTATTTCCATATTTCTCTATAGGACCATGGGAACATTGCACATTACATCTTGTGTGTGCA +TGCACACACACACACGTACATGTGCTTTTGTGCATGCGTGCACATGTTCAGCTAATTTAC +GTGGTAAATACAACTCTTCCTTCTGATTTCAATATGCATAATCTCATTTAATATTTGAGC +TCTCCTGACAGACAGTTTGTTCAGCAAATACTGAGAAACACTCACCATCAGTTTAGAATA +TAAAATTCCCTTAACACCCATCTGAGTTATTTGTCTGAATGTCTTCTACAAAGGCCTCAG +CCCTATAACTAAAATGAGATAGACATGAGTGCACAGTTGTTCATTGTTCTTTCACTTGAC +TTATTAATCGTTATATGATTTACTGGATTTGCTTCTTTTTTTTACAATAGCTTTATTGAG +ATATAGTTTACATACTGTCAGGCCTCTGAGCCTAAGCTAAGCCATCATATCCCCTGTGAC +CTAAATGTACACATGTAGGTGGCCTGTTCCTGCCTTAACTGATGACATTCTACCACAAAA +GAAATGAAAATGGCCTGTTCCTGCCTTAACTGATGGCATTATCTTGTGAAATTCCTTCTT +CTGGCTCAAAAGCCCCTTTACTGAGCACCTTGTGACCTCTACTCCTGCCTGCCAGAGAAC +AACCTCCCTTTTTCCTTTACTTACCTAAATCCTATAAAACGGTCCTACCCCATCTCCTTT +CGCTGACTCTCTTTTCGGACTCAGCTTGCCTGCACCTAGGTGATTAAAAGCTTTATTGCT +CACACAAAGCCTGTTTGGTGGTCACACAGACACACATGAAATTTGGTGCCGTGACTCGGA +TCAGGGGACCTCCCTTAGGAGACCAATCCCCTGTCCTCCTGTTCTTTGCTCCGGAAGAAA +GATCCACCTACGACATCAGTTCCTCTGACCAACCAGCCCAAGGAACATCTCACCGATTTT +AAATCCGGTAAGCAGCCTCTTTTTACTCTCTTCTCCAACCTCCCTCACTATCCCTCAACC +TCTTTCTCCTTTCAATCTTGGCGCCACACTTCAATCTCTCCCTTCTCTTAATTTCAATTC +CTTTCATTTTCTGGTAGAGACAAAGGAGACACGTTTTATCCCTGGACCCAGAACTCCGGC +GCTGGTCACGGACTGGGAAGGCAGGCTTCCCTTGGTGTTTAATCATCGCAAGGACGCCTC +TGATTATTCACCCACGTTTCAGAGGTGTCAGACCACGCAGGGACACCTGCCTTGGTCCTT +CACCCTTAGTGGCAAGTCCCACTTTTCTGGGGGAAGGGCAAGTACCCCAGCCCCTTCTCT +CCGTGTCTCTACCCCTCTCCGCTTTTCTGGAGGAGGGTTAAGAACCCCTCAACCCCTTCT +CCTTCACTCTTAGCGGCAAGTCCCGCTTTTCTAGGGGGCAAGAACCCCCAATCCCTTATT +TCTGTGCCCTGACCTCTTATCTCTGCACCCCAATCCCTTATTTCCATGCCCCAGCCTCTT +ATCTCTGTACCCCATCCCTTATTTCTGCACTCTGACCTCTTATCTCTGTGCCCCAATCCC +TTATTTCTGCACCCCGACCTCTTATCTCTGCACCCCGATCCCTTATTTCCATGCCCAGAT +CTCATCTCTGCGCCCCCATCTCTTATTTCCACACTCCGACCTCTTATCTCTGCGCCCCAA +CCCCTTATTTCTGCACCCCGACCCCTTTCTCGCTTTTCTGGAGGGTAAGAACCCCCGAAC +CCCTTCCCTCCGTGTCTCTACTCTCTCTTTTCTCTGGGCTTGCCTCCTTCACTATAGGCA +ATCTTCCACCCTCCATTCCTCTTTCTTCTCCCTTAGCCTGTGTTCTTAAGAACTTAAAAC +CTCTTCAATTCTCACCTGACCTAAAATCTAAGCATCTTATTTTCTTCTGCAATGCCGCTT +GACCCCAATACAAACTCGACAGTAGTTCCAAATAGTCAGAAAATGGCACTTTCAATTTTT +CCATCTTGCAAGATCTAAATAATTCTTGTCGTAAAATAGGCAAACTGTCTGAGGTGCCTG +ACGTCCAGGCCTTCTTTTACACATCAGTCCCTCCCTAGTCTCTGTGCCCAGTGCAACTCA +TCCCAAATCTTCCTTCTTTCCCTCCCGCCTGTCCCCTCAGTCCCAACCCCAAGCGTCTTT +GAGTCTTTCTAATCTTCCTTTTCTACAGACCCATCTGACCTCTCCCTTCCTCCCCAGGCT +GCTCCTCGCCAGGCTGAGCTATGTCCCAATTCTTCCTCAGCCTCTGCTCCTCCACCCTAT +AATCCTTCTACCACCTCCCCTCTTCACACCTGGTCCGGCTTATAGTTTCGTTCAGTGACT +AGCCCTCCCTCACCTGCCCAGCAATTTACTCTTAAAAAGGTGGCTGAAGCTAAAGGCATA +GTCAAGGTTAATGCTCCTTTTTCTTTATCAGACCTCTCCCAAATCAGTGAGCGTTTAGGC +TCTTTCATCAAATATGAAAAACCCAGCCCGGTTCATGGCTCATTCGGCAGCAACCCTGAG +ACGCTTAACAGCCCTAGACCCTAAAAGGTCAAAAGGCCGTCTTATTCTCAATATACATTT +TATTACCCAATCTGCTCCCGACATTAAATAAAACTCCAAAAATTAAATTCCGGCCCTCAA +ACCCTACAACAACACTTAATTAACCTCACCTTCAAGGTGTACAATAATAGAGGCAGCCAA +GTAGCAACATATTTCTGAGTTGCAATTCTTTGCCTCCACTGTGAGACAAACCCCAGCCAC +ATCTCCAGCACACAAGAACTCCAAACTCCTAAACTGCAGCTGCCAGGGGTTCCTCTAGAA +CCTCCTCCCCCAGAGGCTTGCTACAAGTGCCAGAAATCTGGCCACTGGGCCAAGGAATGC +CCACAGCCCGGGATTCCTCCTAAGCCATGTCCCATCTGTGCGGGACCCCACTGAAAATTG +GACTGTTCAACTCACCTGGCAGCCACTTCCAGAGCCCCTGGAACTCTGGCCCAAGGCTCT +CTGACTCCTTCCCAGATCTTCTCAGCTTAGCAGCTGAAGACTGACACTGCCCGATGGCCT +CAGAAACCTACAGGACCATCACAGACGTTCTAGGTAACTCTCACAGTGGGGGGTAAGTCC +GTCCCCTTCTTGATCAATACGGAGGCTACTCACTCCACATTACTTTGTTTTCAAGGGCCT +GTTTCCCTTGCTTCCATAACTGTTGTGCGTACTGACAGCCAGGCTTCTAAACCTCTTAAA +ACTCTGCAACTCTGGTGCCAACTCAGGCAATACTCTTTTAAGCACTCCTTTTTAGTTATC +CCCACCTGCCCGGTTCCCTTATTAGGCCAAGACACTTAAACTAAATTATCTGCTTCCCTG +ATTATTCCTGGGCTACAGCCACACCTCATTGCCACCTTTTCCCCCAGTTCAAAGCCTCCT +TCACATCCTCCCCTTGTATCTCCCCACCTTAACCCACAAGTATAAGACACCTCTACTCCC +TCCTTAGCGACCGATCATGCACCCCTTACCATCCCATTAAAACCTAATCACTCTTACCTC +GCTCAGTGCCAATATCCCATCCCACAGCATGCTTTGAAAGGATTAAAGCCTGTTATCACT +CGCCTGTTACAGCATGGCCTTTTAAAGCATATAAACTCTTCTTACCATTCCCCCATTTTA +CCTGTCCTAAAACCAGACAAGCCTTACAAGTTAGTTCAGGATCTGCGCCTTATCAACCAA +ATTGTTTTGCCTATCCACCCCATGGTGCCAAACCCGTATACTCTCCTATCCTCAATACCT +CCCTCTACCACCCGTTATTCTGTTCTGGATCTCAAACATGCTTTCTTTACTGTTCCTTTG +CACCCTTCATCCCAGCCTCTCTTTGCTTTCACTTAGACTGACCCTGACACCCATTAGGCT +CAGCAAATTACCTGGGCTGTACTGCCGCAAGGCTTCACAGACAGCCCCCATTACTTCAGT +CAAGCCCAAATTTCATCCTCATCTGTTACCTATCTTGGCATAATTCTCATAAAAACACAT +GTGCTCTCCCTGCTGATCGTGTCCGATTAATCTCCCAAACCTCAATCCCTTACAAAACAA +TAACTCCTTTCCTTCCTAGGCTTGGTTAGTGCGGTCAGAATTCTTACACAAGAGCCAGGA +CCGCACCCTGTAGCCTTTCTGTCCAAACGACTTAACCTTACTGTTTTAGCCTAGCCCTCA +TGTCTCCATGCAGCGGCTGCTGCCGCCCTAATACTTTTAGAGGCCCTAAAAATCACGAAC +TATGCTCAACTCACTCTCTACATTTCTTATAACTTCCAAAATCTATTTTCTTCCTCATAC +CTGACGCGTATACTTTCTGCTCCCCGGCTCCTTCAGCTGTACTCACTCTTTGTTAAGTCC +CACAATTACCATTGTTCCTGGCGTGGACTTCATTCTGGCTCCCACATTACTCCTGATACC +ACACCTGACCCCCATGCCTGTATCTCTCTGATCCACCTGACATTCACCCCATTTCCCCAT +ATTTCCTTCTTTCCTGTTCCTCACCCTGATCACGCTTGATTTATTGATGGCGGTTCCACC +AGGCCTAATCGCCACACACCAGCAAAGGCAGGCTATGCTATAGTACAAGCCACTAGCCCG +CCTCTTAGAACCTCTCATTTCCTTTCCATCGTGGAAATCTATCCTCAAGGAAATAACTTC +TCAGTGTTCCATCTGCTATTCTACTACTCCTCAGGGATTATTCAGGCCCCCTCCCTTCCC +TACACATCAAGCTCGAGGATTTGCCCCCACCCAGGACTGGCAAATTAGCTTTACTCAACA +TGCCCCAAGTCAGAGAACTAAAATACCTCTTAGTCTAGGTAGACACTTTCACTGGATAGG +TAGAGGCCTTTCCTACAGGGTCTGAGAAGGCCACCGCAGTCATTTCTTCCCTTCTGTCAG +ACCTAATTCCTCAGTTTAGCTTTCCCATCTCTATACAGTCTGATAACAGACTAGCCTTTA +TTAGTCAAATCAGCCAAGCAGTTTTTCAGGCTCTTGGTATTCAGTGAAACCTTTATATCC +CTTACAGTCCTCCGTCTTCAGGAAAGGTAGAATGGACTAATGGTCTTTTAAAAACACACC +TCACCAAGCTCAGTCACCAACTTTAAAAGGACTGGACAATACTTTTACCTTTTTCTTTTC +TCAGAATTCAGGCCTGCCCTCGGAATGTTACAGGGTACGGTCCATTTGAGCTCCTGTATG +GATGCTCCTTTTTATTAAGCCCCAGTCTCATTTCAGACACCAGACCAACTTAGACTGTGC +CCCCCAAAAAACTTGTCATCCCTACTATCTTCTGTCTAGTCATACTCCTATTCACCATTC +TCAACTACTCATACATGCCCTGCTCTTGTTTACACTGCTGGCTTACACTGTTTTTCCAAG +CTGTCACAGCTGATATCTCCTGGTGCTATCCCCAAACTGCCACTCTTAACTCTTGAAGTA +AATAAATAATCTTTGCTAGCAGGACTATGCTGAATCTCCTTAGGCACTCTCTAATTAGAT +GTCCTGGGTCCTCCCAATTCTTAGACCTTTAATACCTGTTTTTCTCCTCCTCTTATTCCG +TTTAGTTTTTCAATTCATACAAAACCGTATCCAGGCCATCACCAATAATTCTAAATGACA +AATGTTTCTTCTAACAGTCCCACAATATCACCCCTTACCACAAAATCTTCCTTCAGCTTA +ATCTCTCCCACTCTAGGTTCCCGTGCCGCCCCTAATCCCGCTCGAAGCAGCCCTGAGAAA +CATCGCCAATTATCTCTCCATACCATCCCCCAAAATTTTCGCCATCCCAACGCTTTACCA +CTATTTCCTTTTATTTTTCATATTAATATAAGAAGACAGGAATGTCAGGCCTCTAAGCCC +AAGCTAAGCCATCATATCCCCTGTGACCTGCACTTACACATCCAGATGGCCGGTTCCTGC +CTTAACTGATGACATTCCACCACAAAAGAAATGAAAATGGCCTGTTCCTGCCTTAACTGA +TGGCATTATCTTGTGAAATTCCTTCTCCTGGCTCATCCTGGCTCAAAAGCTCCCCTACTG +AGCACCTTGTGACGACCACTCCTGCCTGCCAGAGAACAACCCCCCTTTTTCCTTTACCTA +CCCAAATCCTATAAAACGGCCCCGCCCCTATCTCCCTTTGCTGACTCTCTTTTCGGACTC +AGCCCGCCTGCACCCAGGTGATTAAAAGCTTTATTGCTCACACAAAGCCTGTTTGGTGGT +CTCTTCACACAGATGCGCATGAAACATACTATACCATTTATCCTTTTAAAATGTACTATC +CGATGGTTTTTAGTGTATTCAGGGTTGCTCTAATTTTAGAATTAGTATCTAATTAGATAA +TCAGTATCTAATTTTAGAATATTTCACCCCCAAAAGCCTCATTTTTATTAACAGCCACTC +CCCCTTTCTTTCACCCCAGCCCCTGGCAAACACTAATCTACTTTCTGACTCTATGGATTT +TCCTCTTCTGGTGTATTTCGCCTTTTCTTTCACAGAATTACACAAATTATCTCAACCCCA +ATCAGTCACCTGGCATGTTTCACTTGGGGATTCAAGTCAGAGCTATATCTCCATTAATAG +GAAAAATGTATATTTAAAAATCTCTTTTAAGAGAAAATAATCTTGAGCTTATGGCTTAAA +GAATAGTGTCTTATAAATGATGAAGCTTCCTTAGATGCGTTAATTAATTTCAACAAATAT +TCACTGAGGCACTGAACCAGTGGGTCTCCAGGTGTGGTTTTTAATGGCCTACATCACAAC +CACCTGGGGATACTTATTAAGGATGTAGATACTTGGGATTTGCCTCACATCTACTAAATT +AGATGTTCAGGGAAGGGGCAAGGGAATCATCATCTTTTTTTTTTTTTTTTTTTTTTTTAG +ACGGAGTCTGGCTGTGTCGCCAGGCTGGAGTGCAGTGTGATGATCTTGGCTCACTGCAAC +CTCCGCCTCCTGGGTTCAAGCGACCGGGTTTCACCATGTTGGCCAGGAGGGTCTAATCCT +CTAACCTCGTGATCCGCTTGCCTTGGCCTCCCAAAGTGCTGGGATTACAAGTGTGAGCCC +CTGCACCTGGCTGGGAATCATCATCTTAACAGGGCCCCTGTGTGCTATTCTTATGCACAC +TAACATTTGCCAATCAGAGGTCCACCCTGTACTAAGGTCTGGGGGTAAAATAGATGATTA +AGACACAGAATTTGATATCAGGTCATTTCAACACACTTAGCCTACACATTATGCCAATGA +TATTTTAGCAAAATTATATAAATACATTGATAGGGGAAGGAGCACTGAAAGAAAAGATTC +CCGGTGATCAACCACTTTCTGCGTCTTACAAAGTACTTTACAAATACTGTTTCTCTTATG +AAGTGCATCACCCAGTACCAGTTGCTGTGACATATATGTTTCCCATATTAGACCTTGCAC +AGAAATACTCATATTAGCATAAATTTATTCATTTATTTAAGAAATGAATATCCATTGAGT +TACAACTATGTGTTCAGCCCTGCTAAGGCAGCAAACAAAATAAAGTCTCTAAACTGTAAA +ACTAAGGAAAGGAGAAGACCAATACAAGAAAGAAAGAACGCTGTGAATAGGGGAAGTCTT +CCTGGAAAGACTAAAATGAACTCCTTCTCAGAGGATATGTAGGATTTGTGTGGGAACAAG +TAGAGGCAACTCCTGTAGTGGAAGATACATAATAAAAGTATGTATAGCACCAAAAAAAAG +AAGCATTTGATTCAGGTTAGATCCAACCAGCAGTCAAGTATCTGCTGGTGTCTGGAATAT +ATGAGAGAGGCTTGAAGAAAATAACTGGAGCAGGACTGTTATTATGTATTGGAGAGCCAT +GTAAGAATCTACAGACAGTACTGAAAATACCTAAGGAATGGCTCTTAACGGAGTGTGTCC +TGATGAAAACTTAGTCACCCCAGGGGAAAATGCATCCATTTAACTCCAAGGGAACATCTA +TACACCTATCAGCATCTATACATCTATCAGCATCTGTACATCTATCTGCATCTGTACATC +TATCAGCATCTATACATCTATCAGCATGAATGAGCTTGAGCTTCCCACTCCGAAAGATCT +GGGAAGCTAAATGACGGTCTCAATCCTCTGTATAGATAAGAGAGGGATGAGCGCTGGAAA +ACAAAGTGGTATCTTTGGTGCACTGATGGTGGAATTCACAACCTGCCGCTGCTCAAATAC +TGGCCCATAAGATTCTGTTCATTCTGCCACTAATCTGGCTATTTTCACTGCAGGTACCTC +AGAATACGGATCTGAACATTAATAAGCAAGGAAAGAACAATAATGGTACACTAAGGTGCC +AGCAGGCAGAGAGAGAGGGAGGAGAAAAACAAAAACCTAGATTAAGCGCATAAAAAATAA +AAATTTTGGAGGACACAGACCAGAACATGAGCATTAATGAGCATTTAGTGAGCTTCAAGT +ACAGTACAAAGACTTTATAGAAATATAAAACTAAAAAAAAACAAAAAACATTGGCTGGGC +GCACTGGCTCACGCCTGTAATCCCAGAGCTTTGGGAGGCCAAGGCGCGTGGATCACATGA +GGTCAGGAGTTCGAGACCAGCCTGGCCGATATGGTGAAATCCCGTCTCTACTAAAAATAC +AAAAAATTAGCCAGGGACAGTGGTGGGTGCCTGTAATCCCAGCTACTTGGAAGGCTGAGG +CAGGAGAATCACTTGAATCCAGGAGGTGGAGGTTGCTGTGAGCCGAGATCGTACCATTGC +GTTCCATCCAGCTTGGGCAACAAGAGTGAGACTGTCTCAAAAAAAAAAAAAAAAAGATAG +TCACTGTTAAGATCAGACCTGGTGGCCTCGATGACACAATGTAAGAAATATCTTAAAGTA +CAGGGTCACAAATATGAAGAGATGAAAAATGATACAGGAAACGTGAGAACTGGACGAGAG +ATCTGAGAGAACTAAGTGTGAATTGTAGGAGTTTCAGAGGGAGGAACAGAAACAGATGGA +TGACTCAAAATAATAAAATCAAACATGTATTTTTGTTTTTCATTTGAACTGAAGAAAGAG +CTGGGCCTTCGGACGAAATTGTTCAATGCACAATCCAGGCAAAGTTAATGACTTTTTAAA +AAGGGTTGGAGAAATTGTGGAGCTTCCAATACAAAAATAAAAAGAAGTGTTTACAAGCTT +CTAGAGACAAGAAACAGGTCACCTTAAAAAAGGAACAAATCAGACCAGTCACAGGCAACT +AATTTGCTTCATCAGAAGTGAGAAAGTAGCAGAAAGCCACTCATAGAATATTGAGAAATT +AGAATTGTAACCTAATTATTTCGTTCCTAAACAAGATAGTAATCCCTGATAGAAGTAAAA +AAAGATGTACGTGGATGGTCTATGCTTTAGGGACTATATCATTCTTGTTCTTTGTGTAAC +CAACAAAATTATCCCAGGAAAAGTGGAGTCAAGGAGATGAACAATGGGGAGGGGTGGGGA +CAGACCGCAGGCTTCATATACATATAATTAAAATGGATAATGAGACACTTGAGAAACGCA +ATAAAACAACCATAAGAGTGCTGAAAATTAATGAGAAACTCTTGAAATCAAATGAGTGTA +AATGCTTAAAATTGAAAAGAAATTCTTGACATTGAAAGGAAAATCATAAAAAGAACCTGG +GATTAAAAATATTAATGTTAAACTCTCCCAATTAAAACTCTGAGTTAAGGTGGGTGAAGG +AAAAGAGAATTTTAAAATTCTCTTTCAGGTTGTGATGATGAGGAAAGGAGGGGAGTAAAT +ACTTTTTTTTTTTCAGACAAACTCTCACTCTGTCACCAGGCTGGAGTGCAGTGGCACGAT +CTCAGCTCACTGCAACTTCCGCCTCCCGTGTTCAAGCGATTCTCCTGCCTCAGCCTTCCG +AGTAGCTGGGATTACAGGTGCCCACCACCACACTCAGCTAATATTTGTATTTTCAGTAGA +AACAGGGTTTCACCATGTTGGTCAGGCCAGTCTCGAACTCCTGACCTCATGTGATCCGCC +CACCTTGACCTCCCCAAGTGCTGGGATTACAGATGTAAGCCACCGTGTCCAGCTGTAAAT +ACGTTCAAAAGAGCTCAATTTTACCGGCGAGGTGACAAGCAGGGTAAAGTTCTTGTTAGA +GAATAACTAGCACTTGTGTCCAGGTATAGTAGTGTGACTATAAGAGTTGATAGAAATGAT +GATCACTCATTAAATAAAGGCAACAGTAAATATAAATACAAGTTGTTCAAGGTTTCATAT +TTTTAAAAAAGATGAAGACAAAAGAAGAAATTGGAGAGAAACAGGTAGATTTTGTAGCAT +AAGTAAAGATAAAAAGGGGGAGAGAAGCAGAAAGGATAACCATTGGGTACTGGGTTTAAT +ACCTGGGTGATGACATACTATGTAAAACGAACCCATGTGACACATGTTTACTTATGTGAC +AAACCTTCGTATGTACCCCAAACCTAAAATAAAAGTTAAAAATAAAAAAGAAAAGCAATT +GAGTAAAATAATAATTTTGTATATTTATATACATATACAACATATATATGCGTGTATATA +CATATATGAGGGAGAAAGAAATGTCACATTGTTATAAACCAATGAAATTGGAAATAAAGT +ATTAAAAAAACAAGTTTTTTATTTTATTTAACATAATCGTATCTGCTTAGAAATGAAAAA +ACACAATACTTGATAAATCTTGGATCAAAAAAGAAAATGCCCTCAATTTATAAAGCTACA +GAGCAAAGAATGCATCTACCAGAATTTATATGACATAGCAAAACTATACTTAGAAAATTG +ATATTGCCTTAAGTGTCTTTATAATTAAAGAAATTTTCTGTATTAAAATTTCTATCAGAT +TATAATTGTAAATATTTTAAATTGAATCAAATTCAAACAATATCCGTTAAGATTCATGAT +TTTCTGTTTTAATATTTAAAGGTAATCAGCTCCATCAGTTGAATAATTTCAGCAAGAGTT +TTTTCTTAAGGCAAAAGAAAAGGCATTGATAAAAATTCAGGATAGTAGAGTTTTGTATGA +AAGCTGACATTCATTAGAATGTTAAAATCAGAACTCTTTACTAACTGGATAACTTTGTAA +GTTTGTATTGCCCATTATGGACTTTGTATTGTTTCCTTTCTGTGGAACATCCATTCAATT +TAAAATGAATCCAGTGGGGTACTCAAGCACAATAACAATTTTGCAATATACGTCAATGTT +ATTATTAATGTTTATGTGTGCAATGAGTTCACCTATCATTTTATTAGCTAAGCTGTAATT +TTAAACATACTTCCTGCATATAGCCAAGGAAGGACTTTGATATGTATGTAGTTATATTCC +TTCAAGTACACTCTTTCTTCAAAAGCTTTCTAAAACCAGTGCACAAACTAAACATGGCCA +GCTGTTAAATGTATCTCTTAAATATTAACTTCTCCAGTTAAAATTAGCACAATACAGGCC +TTACACATAAGAAGCTATCTCTGAGATTATTATCGTATACTTAACTACATTGCTAACAAT +GGATGAGAGCTTAGCAGCTAATAAACCTGCTGTTCCAGCTATAACAAAGGCAAGTTAATG +TATTTGAAAGGAGAGTGATAAAATAACCAAGGCATCATAAACCTAAGATAAACAAAATCA +CCTAGTGGTGACTAATTAACGTAACACATGCAAATCTTCAATATTTTCACTGCTTGAAAT +CCCTTATAATGAATAATTGTATGAGACATTCATATATAAGGACTTCATTTGATTCTTTAT +ATGAAATAAAGTTTCTTCTTCTGTTATGTGAAAATAAAGCCCACTCAAATGAGAACAAAC +AAAAGCTATTTATTCAGAGCTTGTTACAGCAAGAGAGTCAGCCACCATCACTTGCGTTTG +GCAGAAGCTCACAAGCAGGCAGAGGAGAGGGAAAGCTTCATAGCGGAAAAAATAGAAGGC +TTCAGGTGCACCCTGACAAGAGGTTGTTGGCATGGAGAAGCTGGAGGTGGGCAAAAGTAG +AAGTGGGACTTCCTATGCGACTGGGTGGGGGAGCATATTTGGCTTTCTTTGGTTGGTTTT +AAGGTGGAAGCAGGAGCAAAAATTATGGAAGCTGGCAGTTATTGATTACTTGCATTTTTA +GCTGATTGCTACAGAGGTTGTTGTCTGCCTTCCTGGACTGGTTGCTGCAAACTGTTTAAT +TTTTTAAATATGGTCAGAGTTCTGTTTTAAAATACGGTCTGGTGGTTATCTGTTTGCATA +TTTAGTCTCTCAGCTCCCATCCTGTGTCTGAAAAATATTACCTCAATAGAATTTGAATTC +ATAATGGTTTTTAGCAGTATCAGAAGAAACAGACAAGTCTGGCTTCTGAGTAAATATGAT +CAATCTGATCATCCCTTATTTTATATATTTTCTATAATCATACGAATTCCTTCTTGTGAT +AATTTCTGCTATCTCCTATAGTATCTAAATATTTTCCAAGCACATAATTTAAACCCATGA +AAATGGATATGGAAAGCTAAAATAGTCCTGTTTTATTATAAAGCATGTATATGCATTCTA +AAAAAAATTCAGACTATATACAGTCTTGTCTTTGACCAGTATCACAAATAAATTCTTAAG +GGCTAAAGCATATGACATGTATTGATGGAGAATGCATTATAGGTGCAGATTTTCAATTCA +CTTGAATGAAACTTTCAGTAACTTCAGACGTTCAGACCTACACAGATAACTATTCCACGG +CCTACAGCCAAAGGGCCAATGTTAGCTTCATAGTAACAAAAACAACCACCACCATAAGGA +CAATTATTATTACTATTTATGAAACCACTACTGTCATTCAGGGTCTCTGTGTATATTCAT +ATTTAAGTTTATTTAATCTTTGCAACACTTTAAATGTAATGTAAAACAGAAAGATAAGTT +ATATTGACCCATTCATTCACTCAAAAATTAAAATAGTACTTGAACCATTTTTCTTTGAAA +TAAATTTAAGTCTATTCATTTCAATTTGTTTGAATTTCAATTCATATAAATTAATGTATT +CAGGGGCTCTTGAATGAGTCTGTCTGAGGCCCAAAGACAATTGTTTGACGTGGACGAGTC +AGGAGTCAAATCCAAACCTGTCTGCATCCACTGTTTGTGTTCCTAGTCTAATATGTCCAA +AGTTTCCTGTGAACTGAGGCTTATTCAAAGAAAATAAATGTTTTAAATTATCGGCTCCAA +ATAATGATCAAGTTTTTCTACCATTGAAAAGTCAGTGCATAGAGCATATTAAAAAATTAG +AAACATCCAAGGACTACAGGTTTATAGTCTTCCATATTTTCTTCTAAACTGATATTTTGT +TTTCCAGTTGACACAGAGTAATCTTGACATGCAACTTGAAGATGTTAAGTAGGTATTCAT +ATGAGATATGATGCTGACCAGAAGACAGATGTTCATATGTAGTAAAAAATATATTCCATT +ATTAAAATGTATCAAATTAGAAAAATCAAAACTCAACCATCTTCATTCCTTGTTGATGGC +AGAGAGTAAGAGCACACTCTTTATAAAAGACAACTGAGATGCTCATTTTTAAAAAAGCAT +TTTTTAAAAGATCATGCATTTTAAAGGTGTTTCCAATTCACAGATCTACCATAAAAAACT +TAAAACATGCACAAAAATGTGTTTAGAAAGAGACTTATTGCAATGATATTTATGACTACA +ATAATATTCTTCAAGTATATAACATAGATATACAATGATAGAAGAATGGTAAATAAAATG +TAGAATAGCCAAGTGGGGAAATACTATGCAGTGATAAATACCATGTTTACAAAATCAAAT +TATATGTTAATATCCGGATATTTTTTGCTGGTTTTGTTTTTCTTTATTGTAGTAATTTCT +CTTTGTAAATAGTCACAGTACTTTTCAACATCTCCCTTGAAGAATTGGAGTCCATTTCTC +CAACTTCTAGATCTGGGATTGGACATGCGAAAAACTTTTAGAAACAAAAAATTTAGTATT +AATACAATGTTTAGAAGTATACATGTAGTATATTATCATTTTGCAAAGTATAAAACATAT +GAAATAACACTGTGTGGCCAGGCACGGTGGTTCACGCCTGTAATCCCAGCACTTTGGGAG +GCCCAGACGGGCAGATCACGAGGTCAGGGGATCGAGACCATCCTGGCTAACACGGTGAAA +CCCCGTCTCTACTAAAAATACAAAAAAATTAGCCGGAAGTGGTGGCGGGTGCCTGTAGTC +CCAGCTACTCAGGAGGCTGAGGTAGGAGAATGGCATGAACTCGGGAGGCGGAGCTTGCAG +TAAGCCGAGATCGTGCCACTGCACTCTAGCCTGGGCAACAGAGCGAGACTCCGTCTCAAA +AAAAAAATAAAAAAAATTGTGCATTGTTTATGGACAAATGCATAGGTAACAAAATTATTA +AATCACAGGTGGGAAAGGTACACAATTACTTAAAAAATGTAGGTATTTTTCTGGTAATAA +ATGAGAAGGAATAAGGCTGAGAAGTATAAAAGGGATTTCAACTACATTTATAGCTTTTTT +TTTTTTTTTTTGAGATGGAGTCTCGCTGTGTTGCCCAGCCTAGAGTGCAGTGGCGCGATC +TCAGCTCACTGCAAACTCAGCCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGA +GTAGCTGGGATTACAGGCAGCCGCCACCATGCCCAGCTAATTTTTGTATTTTTTAGTAGA +AAAGGGGTTTCACCATCTTGGCCAGGCTGGTCTCAAACTCCTGATCTCATGATCCACCCA +CTTCAGCCTCCCAAAATACTGGGATTACAGGAGTAAGCCACCATGCCTGGCCCATTTATA +GCTTTTAAAATACCAAAAGCATATAAGCTGAATATCATTTTTAACAGACTATTAGAATTG +TTATATTAGTTTGTGTGTGTGAAATATGTCTAACATAAATTTAAAAAGACAGTAAACTTA +GCTGAAAGACAGAAGGAGGAAATGTGTAAGATGAACATTTGCCAGTCAGTATATGAAACA +CCAAATGTTTCTCAGATAAGTTTTAACCAAATAGAATGTACGATGGAAAAAAATCTCATT +CAAAATAATAACCAAGTATACAGCTCCTGGGGATATTTAACAAGAAATTTTTAAAACACA +AATTCTTCAGTCAAATGGTTCTATATAATCTCAAATAAATCTCAGTGGAGATTACTTTGA +TATCCCACAGTGAGACTAGAAATTTCAGTGATATTGTAGATAGTCACAATAGATAAGATC +ATTTTCAATAAGAAGAAATAAAAAGAAAGGTTTTGAAATCTCAATAATTAAACAAATATG +TTACTGATATAGTTTGGATATTGGCCACATCCAAATTTTATGTTGAAATGTAATCTCTAG +TGTTGGAGGTGGGGCCTGGTGGAAGCGGATTGGATCATGGGGTGGATTTCTTGTGAATGG +TTTACCACTGTTCCCTTGGTGCTGTCCTCATGAGATCTGGTGTTTTCAAAGTGTGGCTTC +TCCCCAACACCCGCTTGCTTATGCTTTCGCCATGTGAGAGACCTGCTCCCCCTTCCCCTT +CCGCCATGATTGTAAGCTTCCTGAGGCCTCCCCAGAAGCCGATGCTGCTATACTTCCTGT +ACAGCCTGCAGAAGTGTGAGACAATTAAACCTTTTTCCTTTATAGATTACCCAGTCTCAG +GTATTTATAGCAATGTGAGAACAAACTAATGCAGTTACTTATGCACGGTAATTAATAAAA +CCTCAATGGATCACGATTCTGAAGAAATACAACTTAGTAAAACTTAGTGCCCTCATTTAT +AAGAATTTATTTTTATATTTATTAACAATATGTAATAATTAACTATTCATTTCAAATAGC diff -r d92dd2f040cd -r be072920a53e test-data/fn3.hmm --- a/test-data/fn3.hmm Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/fn3.hmm Wed Jul 21 14:10:08 2021 +0000 @@ -1,4 +1,4 @@ -HMMER3/f [3.2 | June 2018] +HMMER3/f [3.3.2 | Nov 2020] NAME fn3 ACC PF00041.13 DESC Fibronectin type III domain diff -r d92dd2f040cd -r be072920a53e test-data/globins.domtblout --- a/test-data/globins.domtblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/globins.domtblout Wed Jul 21 14:10:08 2021 +0000 @@ -5,11 +5,11 @@ sp|P02185|MYG_PHYCD - 154 dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2 - 149 5.8e-70 221.1 3.3 1 1 6.4e-70 6.4e-70 220.9 3.3 2 149 2 148 1 148 0.99 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2 # # Program: hmmsearch -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpqydies2m/files/6/d/6/dataset_6d69e63c-e7d8-450d-b7f8-3e08a51472f0.dat -# Target file: /tmp/tmpqydies2m/files/8/2/8/dataset_8282288a-91ea-4a46-89c2-d1f3b4e67c52.dat -# Option settings: hmmsearch --tblout /tmp/tmpqydies2m/files/4/6/b/dataset_46bff7ad-a6de-481d-adb4-50ccab8aacb8.dat --domtblout /tmp/tmpqydies2m/files/b/2/5/dataset_b258e52b-de8c-4e23-86d8-c69ebf229c95.dat --pfamtblout /tmp/tmpqydies2m/files/f/b/8/dataset_fb8cde04-dee0-4b38-9125-bf4766986c0c.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpqydies2m/files/6/d/6/dataset_6d69e63c-e7d8-450d-b7f8-3e08a51472f0.dat /tmp/tmpqydies2m/files/8/2/8/dataset_8282288a-91ea-4a46-89c2-d1f3b4e67c52.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/11/working -# Date: Thu May 14 18:54:00 2020 +# Query file: /tmp/tmpzdnl83p_/files/d/7/1/dataset_d71f3df3-1c51-496d-850e-764bcbc1d02f.dat +# Target file: /tmp/tmpzdnl83p_/files/a/a/2/dataset_aa22e5e1-53c6-4de4-93db-352fe45c0b7c.dat +# Option settings: hmmsearch --tblout /tmp/tmpzdnl83p_/files/b/3/0/dataset_b30af9dd-9ae0-4a21-b3b4-7f5c6faf9474.dat --domtblout /tmp/tmpzdnl83p_/files/1/3/b/dataset_13ba9c25-323d-45ff-9914-8a2b298330ee.dat --pfamtblout /tmp/tmpzdnl83p_/files/4/4/6/dataset_446d7608-0577-4f0f-a313-8ef4014324ac.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/d/7/1/dataset_d71f3df3-1c51-496d-850e-764bcbc1d02f.dat /tmp/tmpzdnl83p_/files/a/a/2/dataset_aa22e5e1-53c6-4de4-93db-352fe45c0b7c.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/24/working +# Date: Fri Jul 16 10:33:07 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/globins.pfamtblout --- a/test-data/globins.pfamtblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/globins.pfamtblout Wed Jul 21 14:10:08 2021 +0000 @@ -15,11 +15,11 @@ sp|P02185|MYG_PHYCD 220.9 6.4e-70 1 3.3 1 148 2 148 2 149 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2 # # Program: hmmsearch -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpqydies2m/files/6/d/6/dataset_6d69e63c-e7d8-450d-b7f8-3e08a51472f0.dat -# Target file: /tmp/tmpqydies2m/files/8/2/8/dataset_8282288a-91ea-4a46-89c2-d1f3b4e67c52.dat -# Option settings: hmmsearch --tblout /tmp/tmpqydies2m/files/4/6/b/dataset_46bff7ad-a6de-481d-adb4-50ccab8aacb8.dat --domtblout /tmp/tmpqydies2m/files/b/2/5/dataset_b258e52b-de8c-4e23-86d8-c69ebf229c95.dat --pfamtblout /tmp/tmpqydies2m/files/f/b/8/dataset_fb8cde04-dee0-4b38-9125-bf4766986c0c.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpqydies2m/files/6/d/6/dataset_6d69e63c-e7d8-450d-b7f8-3e08a51472f0.dat /tmp/tmpqydies2m/files/8/2/8/dataset_8282288a-91ea-4a46-89c2-d1f3b4e67c52.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/11/working -# Date: Thu May 14 18:54:00 2020 +# Query file: /tmp/tmpzdnl83p_/files/d/7/1/dataset_d71f3df3-1c51-496d-850e-764bcbc1d02f.dat +# Target file: /tmp/tmpzdnl83p_/files/a/a/2/dataset_aa22e5e1-53c6-4de4-93db-352fe45c0b7c.dat +# Option settings: hmmsearch --tblout /tmp/tmpzdnl83p_/files/b/3/0/dataset_b30af9dd-9ae0-4a21-b3b4-7f5c6faf9474.dat --domtblout /tmp/tmpzdnl83p_/files/1/3/b/dataset_13ba9c25-323d-45ff-9914-8a2b298330ee.dat --pfamtblout /tmp/tmpzdnl83p_/files/4/4/6/dataset_446d7608-0577-4f0f-a313-8ef4014324ac.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/d/7/1/dataset_d71f3df3-1c51-496d-850e-764bcbc1d02f.dat /tmp/tmpzdnl83p_/files/a/a/2/dataset_aa22e5e1-53c6-4de4-93db-352fe45c0b7c.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/24/working +# Date: Fri Jul 16 10:33:07 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/globins.tblout --- a/test-data/globins.tblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/globins.tblout Wed Jul 21 14:10:08 2021 +0000 @@ -5,11 +5,11 @@ sp|P02185|MYG_PHYCD - dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2 - 5.8e-70 221.1 3.3 6.4e-70 220.9 3.3 1.0 1 0 0 1 1 1 1 Myoglobin OS=Physeter catodon GN=MB PE=1 SV=2 # # Program: hmmsearch -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpqydies2m/files/6/d/6/dataset_6d69e63c-e7d8-450d-b7f8-3e08a51472f0.dat -# Target file: /tmp/tmpqydies2m/files/8/2/8/dataset_8282288a-91ea-4a46-89c2-d1f3b4e67c52.dat -# Option settings: hmmsearch --tblout /tmp/tmpqydies2m/files/4/6/b/dataset_46bff7ad-a6de-481d-adb4-50ccab8aacb8.dat --domtblout /tmp/tmpqydies2m/files/b/2/5/dataset_b258e52b-de8c-4e23-86d8-c69ebf229c95.dat --pfamtblout /tmp/tmpqydies2m/files/f/b/8/dataset_fb8cde04-dee0-4b38-9125-bf4766986c0c.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 1 /tmp/tmpqydies2m/files/6/d/6/dataset_6d69e63c-e7d8-450d-b7f8-3e08a51472f0.dat /tmp/tmpqydies2m/files/8/2/8/dataset_8282288a-91ea-4a46-89c2-d1f3b4e67c52.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/11/working -# Date: Thu May 14 18:54:00 2020 +# Query file: /tmp/tmpzdnl83p_/files/d/7/1/dataset_d71f3df3-1c51-496d-850e-764bcbc1d02f.dat +# Target file: /tmp/tmpzdnl83p_/files/a/a/2/dataset_aa22e5e1-53c6-4de4-93db-352fe45c0b7c.dat +# Option settings: hmmsearch --tblout /tmp/tmpzdnl83p_/files/b/3/0/dataset_b30af9dd-9ae0-4a21-b3b4-7f5c6faf9474.dat --domtblout /tmp/tmpzdnl83p_/files/1/3/b/dataset_13ba9c25-323d-45ff-9914-8a2b298330ee.dat --pfamtblout /tmp/tmpzdnl83p_/files/4/4/6/dataset_446d7608-0577-4f0f-a313-8ef4014324ac.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/d/7/1/dataset_d71f3df3-1c51-496d-850e-764bcbc1d02f.dat /tmp/tmpzdnl83p_/files/a/a/2/dataset_aa22e5e1-53c6-4de4-93db-352fe45c0b7c.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/24/working +# Date: Fri Jul 16 10:33:07 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/globins4-emit-1.sto --- a/test-data/globins4-emit-1.sto Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/globins4-emit-1.sto Wed Jul 21 14:10:08 2021 +0000 @@ -1,4 +1,4 @@ ->dataset_x-sample1 -CLDDGAENDNVLTGVLDLNPDEPSEAEPLILILVQSAPTTKAHFQKFVLLTTNMQVEFDT -EIKAHTTMIIGASRAILSSIVQNRMNYYLLLLAKENHSGKERATRKKTDRECLHILGEVI -TITLKREFPMDSNPAHSSRDGTFDLLVSLYRKALRNLY +>dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample1 +CLDDGAENDNVLTGVLDLNNDEPSEAEPLILILVQSAPTTKAHFQKFVLLTTNMQVEFDT +FIKAHTTLIIGASRAILSSIVHNLTRLQKLDKANHSGKDSHTVELNFQEDLGEKIIVGTG +QKLPDDLSARNQACSSRFKSEFQMVSKYLKAKYNPSEKPGLPDSLHTFSSDRQNK diff -r d92dd2f040cd -r be072920a53e test-data/globins4-emit.sto --- a/test-data/globins4-emit.sto Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/globins4-emit.sto Wed Jul 21 14:10:08 2021 +0000 @@ -1,26 +1,26 @@ # STOCKHOLM 1.0 -dataset_x-sample1 -.CLD.DgAENDNVL..TGV.LDLNPD...EPSEAEPLILILVQ.SAPTTK.AH...........FQKFVLLTTN.MQVEFDTEI..KAHT.T.MIIGASRAILSSI.VqNRMN.Y.YLLLLAkEnhsgkE.R..ATRKKTDRECLHILGEVITITL..KREFPMDSNPAHssrDGTFDLLVSLYRKALRNL.Y-..... -dataset_x-sample2 K.PLS.P.AQKKTIR..SAW.LLPGHS...KNDLGQEALVHLDL.AVPAMQ.TMishmlllylhkFPQFEHLSPNvKKLAYAELM..RVGA.I.TTL--LSKQWDTLeA.DATR.R.IPLEEN.D.....V.H..LQKYGLIRKKLQVISALVAKVI..LAGHPENFGPKV...SSAF----IVFYKG--EI.YK..... -dataset_x-sample3 S.MIS.K.RFKVLVE..NLW.LKV-AT...AGDIGSDQLVTFKA.VFTKIY.LT...........FDEFKGEKV-.---HREIAI..KLYTlS.AIAAILNPPLLNL.R.RIYN.H.ELSQLS.A.....L.H..CTQMQSNQEYFLV--NLTVDTI..YETKPTQYREKS...EASENKVTNLVSNALTAN.YR..... -dataset_x-sample4 IsTEC.L.EENEAAK..DVRqEHIVSEmglVDVYSQLLGVLMTT.SIPPTElNR...........MKEKRKLMTR.AGMTTSYAI..RMRG.NhVIHEALSSSAGR-.N.--NQcD.DVVQLS.Q.....K.Y..VTKIYVHPQKIEHITRVLVII-..PYE---THAAEE...DANMEKAVLSVRSRIVTK.FD..... -dataset_x-sample5 -.LIS.E.ASFPLVQnvEIW.VKVFNH...YAEAGNESLIKIVV.TYPDGS.KL...........NHCF-HGK-A.TTCQAANDW..KYDK.E.TFVSTLRKVLASR.K.TRFI.KgKILTVE.N.....E.H..KNSVSVALMRPKLGSNCT--TL..LEVIPSWAGPYE...ESAADKCIPLCASILTSE.YR..... -dataset_x-sample6 -.ALPgD.TGKQYSH..VCW.AN-HAR...--ESGLDILVRYYL.SLPQTL.NF...........FPKFVDITPK.PIMTNNARL..KEEG.A.AVLDA-MNSLLKI.V.QTIE.N.QFWALK.K.....S.F..AHALHVD-KIYKMLNELLIVIV..AAMEPEHDRPHA...DTAMYKVLQKLRKQLGEGrSLiygfp -dataset_x-sample7 P.KFH.N.STKGEVE..RSY.VKVVSK...VDNEGMEYLKDFLSfSRPHAQ.GK...........FGMLKSLQTL.PGLH-VESC..TTME.I.EVLQNLSTPVTGL.D.SQKG.N.EIKELC.R.....V.HldRRTAHVADETFKTYNNSTILRVaqKVHTMRRFDFAA...ADALESFLSYVPCLIEAQ.YQ..... -dataset_x-sample8 V.ALS.K.MEQTRVK..ALY.YQV---...SARSGAQALAEMLVrAHPDSR.ML...........FNQAEVIQTR.LTLAENAQI.qRGWG.K.MVVKADSKNMTRV.EgEKHG.M.EPKASA.R.....N.H..IPRENVINGFFKLSALKVVKTV..DVELARGITFSG...NAPVCPYFKGFAAVLSEP.YE..... -dataset_x-sample9 A.PLN.A.PGWQDVE..-IW.EYV---...-FHRTIRILRNLLK.EIPWER.RH...........FIKTSTVCLP.IICMGNAKLpwRDGG.T.QGRRALNPSVKQC.QfAKTS.G.SLRQCY.D.....R.QhvAIKDRVLINYFQIVGDLVVDYV..DVKLPQDFNPNL...EADIDRRLFISQRSLNCK.W-..... -dataset_x-sample10 -.TLE.M.QLRTDLS..NVA.VKSLAD...LE-VGLEKLMKLYN.SAKLLH.ALr.........cFEPTTKIVTA.SAPKGLRFV..KHQG.T.KVMTAINQAFADM.E.TNYE.Q.KYQSLR.E.....KyK..IEELSIDPRNFQLLAGRVVVRS..AKPLPILLSRQF...ERVLEEHLHLIGKDLQHK.Y-..... -#=GC RF x.xxx.x.xxxxxxx..xxx.xxxxxx...xxxxxxxxxxxxxx.xxxxxx.xx...........xxxxxxxxxx.xxxxxxxxx..xxxx.x.xxxxxxxxxxxxx.x.xxxx.x.xxxxxx.x.....x.x..xxxxxxxxxxxxxxxxxxxxxx..xxxxxxxxxxxx...xxxxxxxxxxxxxxxxxx.xx..... +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample1 .............-CLDDgAENDNVLTGVLDLNNDEPS.E...........AE.PLILILVQSAPTT.KAH.FQKF...VLL.TTNMQVEFDT..F.I..KAH..TTLIIGASRAILSSIV..-HNLTR---LQKLDkAnhsgkDSHTVELNFQEDLGEKIIVGTGQ.KL....PDDLSARNQACssrFK....SEFQMV +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample2 .............SVLVR.ASTLRVSHAKAKF-ACLNT.QishmlllylhkGR.KKILKQIQVQPKA.YAI.GKRY...EDL.TTH--LRKSV..E.V..KEA..AATVRGRLGAIIVIMK..HTHKMSLHPLTERE.E.....VDLTIMEELMESIGNMVVTII--.--....MVDYLE--EAI...ID....KGFELL +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample3 .............IVEST.DGKSEVQLVWGKVKTGAGEtC...........GA.DALEKFFYVKPAM.GTF.FASY...AEQ.VTAVILMKSE..K.L..GLHanGEEIAEAMQSNVKTKDapGHMKYKFTSLSAA-.A.....TKRTVVPGNLIIRALTTVNMSSN.AL....SALITAVGNQI...KS....KSLSKI +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample4 .............-SLEP.EEKSDVQHVYEQVKSSAIV.L...........GA.QRGNRLLESVPAT.KRSeFTKY..lVVLiTTEFFLAKGS..S.V..VQI.cAETVNKNVGVWVEIYR..HNNGIEIGTMSPWH.A.....-RYE---VNFEIIAESLIIAVKS.TN....QQDYTPCAQEA...QE....EVIKMV +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample5 .............LSVVK.TTVQKVRSVLGEVGFVSAN.M...........GW.EALFKLQAEVMTDfQ-A.KDTFystKNL.VSDSQMTREE..KgM..KKS..VEQIKNGVTSTAIKMQ..EKERNDS--LINHW.C.....NSYAIPYEFSGAIGDCLLAATFK.TTfqrsANE-AISSDN-...LE....VFVAM- +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample6 .............LPTIQ.-YKQKVQPLWAGVHEVADT.K...........GR.EMTQLASLLFFNA.ATK.FK-F...QQL.RSDVRVHFSP..D.W..AQH..GREAIAIIRD-LDTLL.qKELNFVISAISDRH.H.....ANLKADVEQYKVLSGMMLQTLAErHL....IYDFSEKREAT...LD....KLMKSV +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample7 pedlnypkaerrfSQMMA.LEKQKPRKVWGPVRFIH-V.K...........SA.TTMGKFVQSTPTV.QSY.FKHV...QGL.SGEDEMGSVHldQ.V..TAH..IADIPGASYKMPRI-R..EVRGKKFNTLADLQ.N.....KRLEVPFKAQ---QAMIIAVNNL.EV....ETEEKEPVTAA...LDgatrKASQLA +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample8 .............AHLEN.RELQMVAAWLGLVQTGADH.A...........GEqNIVLKLYVQFDSR.QPY.LTKF...GGK.KTERHFSASM..D.S..QSE..GRNNIDALKRAMHSVI..NSITCNASNLSESH.I.....HQVDVVDMGFEAVSRDLVDEIES.GH....APNYREYIKCY...MQ....KLLNVI +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample9 .............VVLNE.KEKRRIAAAWGSVTTPLME.L...........VN.EILIKLFVMTPQA.RKY.YDRI...DKL.ETKNSKQA-A..Q.VhvKIH..ASQVIMRIRDVLAK--..---F----HLSQDH.I.....RKIQIDDVQLSALALHAFSMKAS.SV....RGDHTPQVDGS...MQ....AYLHLI +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample10 .............LRLSE.REHLAEVHYWFAVGLHADE.R...........GH.TAINKVFVIYPEV.TTF.LDGF...GNF.NEEAAMNVSE..I.V..KAH..TY-VLEALTDAMRKEM..IMDKNTVTKLAIPH.I.....KQNQVPIEWYKLFGHKLIGNIEN.HI....S--QASSVAEG...IT....RIFNIV +#=GC RF .............xxxxx.xxxxxxxxxxxxxxxxxxx.x...........xx.xxxxxxxxxxxxx.xxx.xxxx...xxx.xxxxxxxxxx..x.x..xxx..xxxxxxxxxxxxxxxx..xxxxxxxxxxxxxx.x.....xxxxxxxxxxxxxxxxxxxxxxx.xx....xxxxxxxxxxx...xx....xxxxxx -dataset_x-sample1 ... -dataset_x-sample2 ... -dataset_x-sample3 ... -dataset_x-sample4 ... -dataset_x-sample5 ... -dataset_x-sample6 gmp -dataset_x-sample7 ... -dataset_x-sample8 ... -dataset_x-sample9 ... -dataset_x-sample10 ... -#=GC RF ... +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample1 S..KYL..KAKYnpseKpglpdslhtfssdrqnk +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample2 R..IVL..NNEF....L................. +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample3 S..EYL..SEAF....R................. +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample4 QnvGIM..WHMM....N................. +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample5 I..HS-..-DNW....K................. +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample6 M..TDLthLDQH....Kp................ +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample7 S..AEF..ARPY....-................. +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample8 T..KHL..KNKS....E................. +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample9 C..KG-..TRKW....M................. +dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2-sample10 R..WLA..ADQL....K................. +#=GC RF x..xxx..xxxx....x................. // diff -r d92dd2f040cd -r be072920a53e test-data/globins4.hmm --- a/test-data/globins4.hmm Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/globins4.hmm Wed Jul 21 14:10:08 2021 +0000 @@ -1,5 +1,5 @@ -HMMER3/f [3.3 | Nov 2019] -NAME dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2 +HMMER3/f [3.3.2 | Nov 2020] +NAME dataset_4d0de504-1e4d-41c4-aebc-164c97efd566 LENG 149 ALPH amino RF no @@ -7,7 +7,7 @@ CONS yes CS no MAP yes -DATE Thu May 14 18:27:55 2020 +DATE Fri Jul 16 10:31:05 2021 NSEQ 4 EFFN 0.964844 CKSUM 2027839109 diff -r d92dd2f040cd -r be072920a53e test-data/globins4.hmm2 --- a/test-data/globins4.hmm2 Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/globins4.hmm2 Wed Jul 21 14:10:08 2021 +0000 @@ -1,4 +1,4 @@ -HMMER2.0 [converted from 3.3] +HMMER2.0 [converted from 3.3.2] NAME dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2 LENG 149 ALPH Amino diff -r d92dd2f040cd -r be072920a53e test-data/jackhmmer.domtblout --- a/test-data/jackhmmer.domtblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/jackhmmer.domtblout Wed Jul 21 14:10:08 2021 +0000 @@ -93,11 +93,11 @@ MYG_MUSAN - 148 sp|P02024|HBB_GORGO - 147 1.6e-44 142.7 0.3 1 1 1.8e-44 1.8e-44 142.6 0.3 8 146 2 141 1 142 0.96 - # # Program: jackhmmer -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpfvu1k4r6/files/e/a/d/dataset_ead1ef79-dd40-459b-b072-01fc401e229a.dat -# Target file: /tmp/tmpfvu1k4r6/files/c/9/e/dataset_c9eb6990-14c2-41da-9304-1bdf155f29e9.dat -# Option settings: jackhmmer -N 5 --tblout /tmp/tmpfvu1k4r6/files/c/c/a/dataset_cca87e56-6fd4-49f3-b29f-dca9b665fb4e.dat --domtblout /tmp/tmpfvu1k4r6/files/a/9/3/dataset_a93530ef-2a8d-4611-9764-b317aa42a6b4.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --wpb --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpfvu1k4r6/files/e/a/d/dataset_ead1ef79-dd40-459b-b072-01fc401e229a.dat /tmp/tmpfvu1k4r6/files/c/9/e/dataset_c9eb6990-14c2-41da-9304-1bdf155f29e9.dat -# Current dir: /tmp/tmpfvu1k4r6/job_working_directory/000/3/working -# Date: Thu May 14 18:30:01 2020 +# Query file: /tmp/tmpzdnl83p_/files/0/1/5/dataset_0156c4e5-db19-44b9-9720-26a662d40967.dat +# Target file: /tmp/tmpzdnl83p_/files/4/1/d/dataset_41d1e750-65d7-48a9-819a-f7188b5b01b8.dat +# Option settings: jackhmmer -N 5 --tblout /tmp/tmpzdnl83p_/files/7/d/e/dataset_7de0eeb5-83b6-418a-88c5-21c3999368bb.dat --domtblout /tmp/tmpzdnl83p_/files/a/0/b/dataset_a0b2025a-6ab0-46b2-b566-fa012cd86bf9.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --wpb --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/0/1/5/dataset_0156c4e5-db19-44b9-9720-26a662d40967.dat /tmp/tmpzdnl83p_/files/4/1/d/dataset_41d1e750-65d7-48a9-819a-f7188b5b01b8.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/30/working +# Date: Fri Jul 16 10:33:43 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/jackhmmer.out --- a/test-data/jackhmmer.out Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/jackhmmer.out Wed Jul 21 14:10:08 2021 +0000 @@ -1,15 +1,15 @@ # jackhmmer :: iteratively search a protein sequence against a protein database -# HMMER 3.3 (Nov 2019); http://hmmer.org/ -# Copyright (C) 2019 Howard Hughes Medical Institute. +# HMMER 3.3.2 (Nov 2020); http://hmmer.org/ +# Copyright (C) 2020 Howard Hughes Medical Institute. # Freely distributed under the BSD open source license. # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -# query sequence file: /tmp/tmpfvu1k4r6/files/5/c/1/dataset_5c1435bb-ab6c-4203-863c-578c4a331ea1.dat -# target sequence database: /tmp/tmpfvu1k4r6/files/0/c/2/dataset_0c23de62-c430-473e-92ee-a18da9f58231.dat +# query sequence file: /tmp/tmpzdnl83p_/files/2/7/9/dataset_27979eae-6ed4-4ade-aa69-7ece7b993e22.dat +# target sequence database: /tmp/tmpzdnl83p_/files/e/6/d/dataset_e6d4b38b-8770-49ed-98bb-842ce026d3c8.dat # max ASCII text line length: unlimited # Vit filter P threshold: <= 0.001 # Fwd filter P threshold: <= 1e-05 # random number seed set to: 4 -# number of worker threads: 1 +# number of worker threads: 0 # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: sp|P02185|MYG_PHYCD [L=154] @@ -606,8 +606,8 @@ Passed Fwd filter: 44 (0.977778); expected 0.0 (1e-05) Initial search space (Z): 45 [actual number of targets] Domain search space (domZ): 44 [number of targets reported over threshold] -# CPU time: 0.04u 0.00s 00:00:00.04 Elapsed: 00:00:00.04 -# Mc/sec: 20.54 +# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.03 +# Mc/sec: 28.10 @@ New targets included: 44 @@ New alignment includes: 45 subseqs (was 1), including original query @@ -1268,8 +1268,8 @@ Passed Fwd filter: 45 (1); expected 0.0 (1e-05) Initial search space (Z): 45 [actual number of targets] Domain search space (domZ): 45 [number of targets reported over threshold] -# CPU time: 0.22u 0.00s 00:00:00.22 Elapsed: 00:00:00.22 -# Mc/sec: 4.45 +# CPU time: 0.13u 0.00s 00:00:00.13 Elapsed: 00:00:00.13 +# Mc/sec: 7.65 @@ New targets included: 1 @@ New alignment includes: 46 subseqs (was 45), including original query @@ -1930,8 +1930,8 @@ Passed Fwd filter: 45 (1); expected 0.0 (1e-05) Initial search space (Z): 45 [actual number of targets] Domain search space (domZ): 45 [number of targets reported over threshold] -# CPU time: 0.20u 0.00s 00:00:00.20 Elapsed: 00:00:00.20 -# Mc/sec: 5.00 +# CPU time: 0.14u 0.00s 00:00:00.14 Elapsed: 00:00:00.13 +# Mc/sec: 7.59 @@ New targets included: 0 @@ New alignment includes: 46 subseqs (was 46), including original query @@ -2547,8 +2547,8 @@ Passed Fwd filter: 45 (1); expected 0.0 (1e-05) Initial search space (Z): 45 [actual number of targets] Domain search space (domZ): 45 [number of targets reported over threshold] -# CPU time: 0.05u 0.00s 00:00:00.05 Elapsed: 00:00:00.04 -# Mc/sec: 20.84 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 +# Mc/sec: 33.36 @@ New targets included: 45 @@ New alignment includes: 46 subseqs (was 1), including original query @@ -3209,8 +3209,8 @@ Passed Fwd filter: 45 (1); expected 0.0 (1e-05) Initial search space (Z): 45 [actual number of targets] Domain search space (domZ): 45 [number of targets reported over threshold] -# CPU time: 0.22u 0.00s 00:00:00.22 Elapsed: 00:00:00.24 -# Mc/sec: 3.96 +# CPU time: 0.13u 0.00s 00:00:00.13 Elapsed: 00:00:00.12 +# Mc/sec: 7.64 @@ New targets included: 0 @@ New alignment includes: 46 subseqs (was 46), including original query diff -r d92dd2f040cd -r be072920a53e test-data/jackhmmer.tblout --- a/test-data/jackhmmer.tblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/jackhmmer.tblout Wed Jul 21 14:10:08 2021 +0000 @@ -93,11 +93,11 @@ MYG_MUSAN - sp|P02024|HBB_GORGO - 1.6e-44 142.7 0.3 1.8e-44 142.6 0.3 1.0 1 0 0 1 1 1 1 - # # Program: jackhmmer -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpfvu1k4r6/files/e/a/d/dataset_ead1ef79-dd40-459b-b072-01fc401e229a.dat -# Target file: /tmp/tmpfvu1k4r6/files/c/9/e/dataset_c9eb6990-14c2-41da-9304-1bdf155f29e9.dat -# Option settings: jackhmmer -N 5 --tblout /tmp/tmpfvu1k4r6/files/c/c/a/dataset_cca87e56-6fd4-49f3-b29f-dca9b665fb4e.dat --domtblout /tmp/tmpfvu1k4r6/files/a/9/3/dataset_a93530ef-2a8d-4611-9764-b317aa42a6b4.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --wpb --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpfvu1k4r6/files/e/a/d/dataset_ead1ef79-dd40-459b-b072-01fc401e229a.dat /tmp/tmpfvu1k4r6/files/c/9/e/dataset_c9eb6990-14c2-41da-9304-1bdf155f29e9.dat -# Current dir: /tmp/tmpfvu1k4r6/job_working_directory/000/3/working -# Date: Thu May 14 18:30:01 2020 +# Query file: /tmp/tmpzdnl83p_/files/0/1/5/dataset_0156c4e5-db19-44b9-9720-26a662d40967.dat +# Target file: /tmp/tmpzdnl83p_/files/4/1/d/dataset_41d1e750-65d7-48a9-819a-f7188b5b01b8.dat +# Option settings: jackhmmer -N 5 --tblout /tmp/tmpzdnl83p_/files/7/d/e/dataset_7de0eeb5-83b6-418a-88c5-21c3999368bb.dat --domtblout /tmp/tmpzdnl83p_/files/a/0/b/dataset_a0b2025a-6ab0-46b2-b566-fa012cd86bf9.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --wpb --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/0/1/5/dataset_0156c4e5-db19-44b9-9720-26a662d40967.dat /tmp/tmpzdnl83p_/files/4/1/d/dataset_41d1e750-65d7-48a9-819a-f7188b5b01b8.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/30/working +# Date: Fri Jul 16 10:33:43 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/nhmmer.out --- a/test-data/nhmmer.out Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/nhmmer.out Wed Jul 21 14:10:08 2021 +0000 @@ -1,20 +1,17 @@ # nhmmer :: search a DNA model, alignment, or sequence against a DNA database -# HMMER 3.3 (Nov 2019); http://hmmer.org/ -# Copyright (C) 2019 Howard Hughes Medical Institute. +# HMMER 3.3.2 (Nov 2020); http://hmmer.org/ +# Copyright (C) 2020 Howard Hughes Medical Institute. # Freely distributed under the BSD open source license. # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -# query file: /tmp/tmpqydies2m/files/c/4/e/dataset_c4e67f40-cb86-438e-8bc0-6020ada9fc86.dat -# target sequence database: /tmp/tmpqydies2m/files/a/1/b/dataset_a1b4364c-0e9a-4709-b4ef-ab7e5661d9e9.dat -# hits tabular output: /tmp/tmpqydies2m/files/b/d/d/dataset_bdd87d82-1ce1-4051-8d5f-f7251bf7fd18.dat -# hits output in Dfam format: /tmp/tmpqydies2m/files/d/8/e/dataset_d8ee0d50-d171-4e8a-9c7d-1cbd4394296f.dat -# alignment scores output: /tmp/tmpqydies2m/files/5/1/3/dataset_5139892f-c507-40c4-b43d-f73023c634f4.dat +# query file: /tmp/tmpzdnl83p_/files/9/7/3/dataset_973ac44a-c86b-42ed-b8fe-f747795642c7.dat +# target sequence database: /tmp/tmpzdnl83p_/files/6/5/6/dataset_65678542-5e91-4d72-9409-b7213a529ca0.dat # max ASCII text line length: unlimited # SSV filter P threshold: <= 0.02 # Vit filter P threshold: <= 0.001 # Fwd filter P threshold: <= 1e-05 # input query is asserted as: DNA # random number seed set to: 4 -# number of worker threads: 1 +# number of worker threads: 0 # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MADE1 [M=80] @@ -108,7 +105,7 @@ Residues passing Vit filter: 1612 (0.00244); expected (0.001) Residues passing Fwd filter: 1194 (0.00181); expected (1e-05) Total number of hits: 5 (0.000405) -# CPU time: 0.04u 0.00s 00:00:00.04 Elapsed: 00:00:00.05 -# Mc/sec: 1031.54 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 +# Mc/sec: 2197.54 // [ok] diff -r d92dd2f040cd -r be072920a53e test-data/nhmmer.out.tblout --- a/test-data/nhmmer.out.tblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/nhmmer.out.tblout Wed Jul 21 14:10:08 2021 +0000 @@ -7,11 +7,11 @@ humanchr1/239220001-239550000 - MADE1 DF0000629.2 41 71 304073 304103 304053 304109 330000 + 2.2 6.9 7.2 - # # Program: nhmmer -# Version: 3.3 (Nov 2019) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpqydies2m/files/c/4/e/dataset_c4e67f40-cb86-438e-8bc0-6020ada9fc86.dat -# Target file: /tmp/tmpqydies2m/files/a/1/b/dataset_a1b4364c-0e9a-4709-b4ef-ab7e5661d9e9.dat -# Option settings: nhmmer --tblout /tmp/tmpqydies2m/files/b/d/d/dataset_bdd87d82-1ce1-4051-8d5f-f7251bf7fd18.dat --dfamtblout /tmp/tmpqydies2m/files/d/8/e/dataset_d8ee0d50-d171-4e8a-9c7d-1cbd4394296f.dat --aliscoresout /tmp/tmpqydies2m/files/5/1/3/dataset_5139892f-c507-40c4-b43d-f73023c634f4.dat --notextw -E 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --dna --seed 4 --cpu 1 /tmp/tmpqydies2m/files/c/4/e/dataset_c4e67f40-cb86-438e-8bc0-6020ada9fc86.dat /tmp/tmpqydies2m/files/a/1/b/dataset_a1b4364c-0e9a-4709-b4ef-ab7e5661d9e9.dat -# Current dir: /tmp/tmpqydies2m/job_working_directory/000/17/working -# Date: Thu May 14 18:54:51 2020 +# Query file: /tmp/tmpzdnl83p_/files/8/6/7/dataset_867699d1-2c6c-4367-8540-aa72655041fb.dat +# Target file: /tmp/tmpzdnl83p_/files/1/a/1/dataset_1a1fb3d8-05ff-474e-b627-c162ff1aa7a5.dat +# Option settings: nhmmer --tblout /tmp/tmpzdnl83p_/files/0/a/c/dataset_0ac8367e-7ecc-41a5-a995-09d458438754.dat --dfamtblout /tmp/tmpzdnl83p_/files/d/6/0/dataset_d60239d4-a95a-45fb-9b76-7ccedc277d9e.dat --aliscoresout /tmp/tmpzdnl83p_/files/f/6/e/dataset_f6e4f662-4b72-4e7a-9f18-de39b61bce27.dat --notextw -E 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --dna --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/8/6/7/dataset_867699d1-2c6c-4367-8540-aa72655041fb.dat /tmp/tmpzdnl83p_/files/1/a/1/dataset_1a1fb3d8-05ff-474e-b627-c162ff1aa7a5.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/36/working +# Date: Fri Jul 16 10:34:18 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/phmmer.domtblout --- a/test-data/phmmer.domtblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/phmmer.domtblout Wed Jul 21 14:10:08 2021 +0000 @@ -92,11 +92,11 @@ sp|P02024|HBB_GORGO - 147 HBB2_TRICR - 145 2.7e-46 144.3 0.0 1 1 1.5e-46 3e-46 144.1 0.0 1 145 2 146 2 146 0.98 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2 # # Program: phmmer -# Version: 3.2 (June 2018) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpp4O0Ju/files/000/dataset_45.dat -# Target file: /tmp/tmpp4O0Ju/files/000/dataset_46.dat -# Option settings: phmmer --tblout /tmp/tmpp4O0Ju/files/000/dataset_48.dat --domtblout /tmp/tmpp4O0Ju/files/000/dataset_49.dat --pfamtblout /tmp/tmpp4O0Ju/files/000/dataset_50.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpp4O0Ju/files/000/dataset_45.dat /tmp/tmpp4O0Ju/files/000/dataset_46.dat -# Current dir: /tmp/tmpp4O0Ju/job_working_directory/000/36/working -# Date: Fri Jun 8 12:19:38 2018 +# Query file: /tmp/tmpzdnl83p_/files/6/e/b/dataset_6ebbde12-ebc2-45e1-bca1-5b28034097f2.dat +# Target file: /tmp/tmpzdnl83p_/files/f/5/8/dataset_f5890da8-ad9f-4fc0-908d-0b9dc0c44e28.dat +# Option settings: phmmer --tblout /tmp/tmpzdnl83p_/files/0/d/1/dataset_0d12c973-afff-4faa-9147-e31051f4f5ca.dat --domtblout /tmp/tmpzdnl83p_/files/d/b/2/dataset_db25fae1-b539-436c-860b-dae65bd95d8a.dat --pfamtblout /tmp/tmpzdnl83p_/files/c/1/0/dataset_c100c9b8-9cdb-4b7f-ac1b-0a7658854933.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/6/e/b/dataset_6ebbde12-ebc2-45e1-bca1-5b28034097f2.dat /tmp/tmpzdnl83p_/files/f/5/8/dataset_f5890da8-ad9f-4fc0-908d-0b9dc0c44e28.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/45/working +# Date: Fri Jul 16 10:35:18 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/phmmer.out --- a/test-data/phmmer.out Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/phmmer.out Wed Jul 21 14:10:08 2021 +0000 @@ -1,18 +1,15 @@ # phmmer :: search a protein sequence against a protein database -# HMMER 3.2 (June 2018); http://hmmer.org/ -# Copyright (C) 2018 Howard Hughes Medical Institute. +# HMMER 3.3.2 (Nov 2020); http://hmmer.org/ +# Copyright (C) 2020 Howard Hughes Medical Institute. # Freely distributed under the BSD open source license. # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -# query sequence file: /tmp/tmpp4O0Ju/files/000/dataset_45.dat -# target sequence database: /tmp/tmpp4O0Ju/files/000/dataset_46.dat -# per-seq hits tabular output: /tmp/tmpp4O0Ju/files/000/dataset_48.dat -# per-dom hits tabular output: /tmp/tmpp4O0Ju/files/000/dataset_49.dat -# pfam-style tabular hit output: /tmp/tmpp4O0Ju/files/000/dataset_50.dat +# query sequence file: /tmp/tmpzdnl83p_/files/f/3/7/dataset_f37673ce-2825-4214-827f-9fd8798aa730.dat +# target sequence database: /tmp/tmpzdnl83p_/files/4/8/e/dataset_48ee2b1d-0f10-4a66-bc8d-a3f4938d2e4a.dat # max ASCII text line length: unlimited # Vit filter P threshold: <= 0.001 # Fwd filter P threshold: <= 1e-05 # random number seed set to: 4 -# number of worker threads: 1 +# number of worker threads: 0 # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: MYG_ESCGI [L=153] @@ -62,7 +59,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.67 +# Mc/sec: 2.88 // Query: MYG_HORSE [L=153] Scores for complete sequences (score includes all domains): @@ -111,7 +108,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.81 +# Mc/sec: 3.02 // Query: MYG_PROGU [L=153] Scores for complete sequences (score includes all domains): @@ -159,8 +156,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.81 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 3.01 // Query: MYG_SAISC [L=153] Scores for complete sequences (score includes all domains): @@ -208,8 +205,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.78 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 3.04 // Query: MYG_LYCPI [L=153] Scores for complete sequences (score includes all domains): @@ -257,8 +254,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.74 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 3.06 // Query: MYG_MOUSE [L=153] Scores for complete sequences (score includes all domains): @@ -306,8 +303,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.78 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 3.08 // Query: MYG_MUSAN [L=148] Scores for complete sequences (score includes all domains): @@ -355,8 +352,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.88 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 3.08 // Query: HBA_AILME [L=141] Scores for complete sequences (score includes all domains): @@ -404,8 +401,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.80 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 3.00 // Query: HBA_PROLO [L=141] Scores for complete sequences (score includes all domains): @@ -453,8 +450,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.73 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 3.00 // Query: HBA_PAGLA [L=141] Scores for complete sequences (score includes all domains): @@ -503,7 +500,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.33 +# Mc/sec: 3.03 // Query: HBA_MACFA [L=141] Scores for complete sequences (score includes all domains): @@ -552,7 +549,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.65 +# Mc/sec: 3.00 // Query: HBA_MACSI [L=141] Scores for complete sequences (score includes all domains): @@ -600,8 +597,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.73 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 3.03 // Query: HBA_PONPY [L=141] Scores for complete sequences (score includes all domains): @@ -650,7 +647,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.67 +# Mc/sec: 2.97 // Query: HBA2_GALCR [L=141] Scores for complete sequences (score includes all domains): @@ -699,7 +696,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.68 +# Mc/sec: 3.01 // Query: HBA_MESAU [L=141] Scores for complete sequences (score includes all domains): @@ -748,7 +745,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.41 +# Mc/sec: 3.00 // Query: HBA2_BOSMU [L=141] Scores for complete sequences (score includes all domains): @@ -796,8 +793,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.64 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 3.02 // Query: HBA_ERIEU [L=141] Scores for complete sequences (score includes all domains): @@ -846,7 +843,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.76 +# Mc/sec: 2.92 // Query: HBA_FRAPO [L=141] Scores for complete sequences (score includes all domains): @@ -895,7 +892,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.70 +# Mc/sec: 2.60 // Query: HBA_PHACO [L=141] Scores for complete sequences (score includes all domains): @@ -944,7 +941,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.56 +# Mc/sec: 2.51 // Query: HBA_TRIOC [L=141] Scores for complete sequences (score includes all domains): @@ -993,7 +990,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.35 +# Mc/sec: 2.58 // Query: HBA_ANSSE [L=141] Scores for complete sequences (score includes all domains): @@ -1041,8 +1038,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.52 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.51 // Query: HBA_COLLI [L=141] Scores for complete sequences (score includes all domains): @@ -1091,7 +1088,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.79 +# Mc/sec: 2.44 // Query: HBAD_CHLME [L=141] Scores for complete sequences (score includes all domains): @@ -1139,8 +1136,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 1.87 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.83 // Query: HBAD_PASMO [L=141] Scores for complete sequences (score includes all domains): @@ -1188,8 +1185,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 2.10 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.91 // Query: HBAZ_HORSE [L=141] Scores for complete sequences (score includes all domains): @@ -1238,7 +1235,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.21 +# Mc/sec: 2.95 // Query: HBA4_SALIR [L=142] Scores for complete sequences (score includes all domains): @@ -1287,7 +1284,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.72 +# Mc/sec: 2.98 // Query: HBB_ORNAN [L=146] Scores for complete sequences (score includes all domains): @@ -1336,7 +1333,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.63 +# Mc/sec: 2.92 // Query: HBB_TACAC [L=146] Scores for complete sequences (score includes all domains): @@ -1384,8 +1381,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.82 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 3.01 // Query: HBE_PONPY [L=146] Scores for complete sequences (score includes all domains): @@ -1433,8 +1430,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.02 -# Mc/sec: 1.68 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 3.03 // Query: HBB_SPECI [L=146] Scores for complete sequences (score includes all domains): @@ -1482,8 +1479,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 2.16 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.97 // Query: HBB_SPETO [L=146] Scores for complete sequences (score includes all domains): @@ -1532,7 +1529,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.50 +# Mc/sec: 2.97 // Query: HBB_EQUHE [L=146] Scores for complete sequences (score includes all domains): @@ -1580,8 +1577,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 2.16 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.98 // Query: HBB_SUNMU [L=146] Scores for complete sequences (score includes all domains): @@ -1629,8 +1626,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 2.00 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.91 // Query: HBB_CALAR [L=146] Scores for complete sequences (score includes all domains): @@ -1678,8 +1675,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.01s 00:00:00.03 Elapsed: 00:00:00.02 -# Mc/sec: 1.87 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.78 // Query: HBB_MANSP [L=146] Scores for complete sequences (score includes all domains): @@ -1727,8 +1724,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 1.86 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.75 // Query: HBB_URSMA [L=146] Scores for complete sequences (score includes all domains): @@ -1776,8 +1773,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 1.65 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.74 // Query: HBB_RABIT [L=146] Scores for complete sequences (score includes all domains): @@ -1825,8 +1822,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.57 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.56 // Query: HBB_TUPGL [L=146] Scores for complete sequences (score includes all domains): @@ -1875,7 +1872,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.80 +# Mc/sec: 2.49 // Query: HBB_TRIIN [L=146] Scores for complete sequences (score includes all domains): @@ -1923,8 +1920,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 -# Mc/sec: 2.80 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.55 // Query: HBB_COLLI [L=146] Scores for complete sequences (score includes all domains): @@ -1973,7 +1970,7 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 -# Mc/sec: 2.22 +# Mc/sec: 2.43 // Query: HBB_LARRI [L=146] Scores for complete sequences (score includes all domains): @@ -2021,8 +2018,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 1.82 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.45 // Query: HBB1_VAREX [L=146] Scores for complete sequences (score includes all domains): @@ -2070,8 +2067,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 1.75 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.70 // Query: HBB2_XENTR [L=146] Scores for complete sequences (score includes all domains): @@ -2119,8 +2116,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.03u 0.00s 00:00:00.03 Elapsed: 00:00:00.02 -# Mc/sec: 1.82 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.72 // Query: HBBL_RANCA [L=146] Scores for complete sequences (score includes all domains): @@ -2168,8 +2165,8 @@ Passed Fwd filter: 2 (1); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 1.80 +# CPU time: 0.01u 0.00s 00:00:00.01 Elapsed: 00:00:00.01 +# Mc/sec: 2.69 // Query: HBB2_TRICR [L=145] Scores for complete sequences (score includes all domains): @@ -2204,7 +2201,7 @@ Passed Fwd filter: 1 (0.5); expected 0.0 (1e-05) Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 1 [number of targets reported over threshold] -# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.02 -# Mc/sec: 1.87 +# CPU time: 0.02u 0.00s 00:00:00.02 Elapsed: 00:00:00.01 +# Mc/sec: 2.57 // [ok] diff -r d92dd2f040cd -r be072920a53e test-data/phmmer.pfamtblout --- a/test-data/phmmer.pfamtblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/phmmer.pfamtblout Wed Jul 21 14:10:08 2021 +0000 @@ -673,11 +673,11 @@ sp|P02024|HBB_GORGO 144.1 3e-46 1 0.0 2 146 2 146 1 145 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2 # # Program: phmmer -# Version: 3.2 (June 2018) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpp4O0Ju/files/000/dataset_45.dat -# Target file: /tmp/tmpp4O0Ju/files/000/dataset_46.dat -# Option settings: phmmer --tblout /tmp/tmpp4O0Ju/files/000/dataset_48.dat --domtblout /tmp/tmpp4O0Ju/files/000/dataset_49.dat --pfamtblout /tmp/tmpp4O0Ju/files/000/dataset_50.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpp4O0Ju/files/000/dataset_45.dat /tmp/tmpp4O0Ju/files/000/dataset_46.dat -# Current dir: /tmp/tmpp4O0Ju/job_working_directory/000/36/working -# Date: Fri Jun 8 12:19:38 2018 +# Query file: /tmp/tmpzdnl83p_/files/6/e/b/dataset_6ebbde12-ebc2-45e1-bca1-5b28034097f2.dat +# Target file: /tmp/tmpzdnl83p_/files/f/5/8/dataset_f5890da8-ad9f-4fc0-908d-0b9dc0c44e28.dat +# Option settings: phmmer --tblout /tmp/tmpzdnl83p_/files/0/d/1/dataset_0d12c973-afff-4faa-9147-e31051f4f5ca.dat --domtblout /tmp/tmpzdnl83p_/files/d/b/2/dataset_db25fae1-b539-436c-860b-dae65bd95d8a.dat --pfamtblout /tmp/tmpzdnl83p_/files/c/1/0/dataset_c100c9b8-9cdb-4b7f-ac1b-0a7658854933.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/6/e/b/dataset_6ebbde12-ebc2-45e1-bca1-5b28034097f2.dat /tmp/tmpzdnl83p_/files/f/5/8/dataset_f5890da8-ad9f-4fc0-908d-0b9dc0c44e28.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/45/working +# Date: Fri Jul 16 10:35:18 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/phmmer.tblout --- a/test-data/phmmer.tblout Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/phmmer.tblout Wed Jul 21 14:10:08 2021 +0000 @@ -92,11 +92,11 @@ sp|P02024|HBB_GORGO - HBB2_TRICR - 2.7e-46 144.3 0.0 3e-46 144.1 0.0 1.0 1 0 0 1 1 1 1 Hemoglobin subunit beta OS=Gorilla gorilla gorilla GN=HBB PE=1 SV=2 # # Program: phmmer -# Version: 3.2 (June 2018) +# Version: 3.3.2 (Nov 2020) # Pipeline mode: SEARCH -# Query file: /tmp/tmpp4O0Ju/files/000/dataset_45.dat -# Target file: /tmp/tmpp4O0Ju/files/000/dataset_46.dat -# Option settings: phmmer --tblout /tmp/tmpp4O0Ju/files/000/dataset_48.dat --domtblout /tmp/tmpp4O0Ju/files/000/dataset_49.dat --pfamtblout /tmp/tmpp4O0Ju/files/000/dataset_50.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 1 /tmp/tmpp4O0Ju/files/000/dataset_45.dat /tmp/tmpp4O0Ju/files/000/dataset_46.dat -# Current dir: /tmp/tmpp4O0Ju/job_working_directory/000/36/working -# Date: Fri Jun 8 12:19:38 2018 +# Query file: /tmp/tmpzdnl83p_/files/6/e/b/dataset_6ebbde12-ebc2-45e1-bca1-5b28034097f2.dat +# Target file: /tmp/tmpzdnl83p_/files/f/5/8/dataset_f5890da8-ad9f-4fc0-908d-0b9dc0c44e28.dat +# Option settings: phmmer --tblout /tmp/tmpzdnl83p_/files/0/d/1/dataset_0d12c973-afff-4faa-9147-e31051f4f5ca.dat --domtblout /tmp/tmpzdnl83p_/files/d/b/2/dataset_db25fae1-b539-436c-860b-dae65bd95d8a.dat --pfamtblout /tmp/tmpzdnl83p_/files/c/1/0/dataset_c100c9b8-9cdb-4b7f-ac1b-0a7658854933.dat --notextw -E 10.0 --domE 10.0 --F1 0.02 --F2 0.001 --F3 1e-05 --EmL 200 --EmN 200 --EvL 200 --EvN 200 --EfL 100 --EfN 200 --Eft 0.04 --seed 4 --cpu 0 /tmp/tmpzdnl83p_/files/6/e/b/dataset_6ebbde12-ebc2-45e1-bca1-5b28034097f2.dat /tmp/tmpzdnl83p_/files/f/5/8/dataset_f5890da8-ad9f-4fc0-908d-0b9dc0c44e28.dat +# Current dir: /tmp/tmpzdnl83p_/job_working_directory/000/45/working +# Date: Fri Jul 16 10:35:18 2021 # [ok] diff -r d92dd2f040cd -r be072920a53e test-data/uniprot_globins_match.out --- a/test-data/uniprot_globins_match.out Thu Jan 14 15:43:54 2021 +0000 +++ b/test-data/uniprot_globins_match.out Wed Jul 21 14:10:08 2021 +0000 @@ -1,15 +1,15 @@ # hmmsearch :: search profile(s) against a sequence database -# HMMER 3.3 (Nov 2019); http://hmmer.org/ -# Copyright (C) 2019 Howard Hughes Medical Institute. +# HMMER 3.3.2 (Nov 2020); http://hmmer.org/ +# Copyright (C) 2020 Howard Hughes Medical Institute. # Freely distributed under the BSD open source license. # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -# query HMM file: /tmp/tmpqydies2m/files/1/e/c/dataset_1eca2f81-02d4-4cd0-9081-3ea0f7eb36d7.dat -# target sequence database: /tmp/tmpqydies2m/files/a/4/d/dataset_a4d3f992-2c56-4231-9590-fe0ab1f6413b.dat +# query HMM file: /tmp/tmpzdnl83p_/files/f/6/6/dataset_f66fafa4-758d-4ace-89be-ff71fce4f56c.dat +# target sequence database: /tmp/tmpzdnl83p_/files/0/d/9/dataset_0d912a57-511c-4a51-a642-30fdf00f581c.dat # max ASCII text line length: unlimited # Vit filter P threshold: <= 0.001 # Fwd filter P threshold: <= 1e-05 # random number seed set to: 4 -# number of worker threads: 1 +# number of worker threads: 0 # - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - Query: dataset_a435d3bd-3e95-4c54-859f-736e9bc413b2 [M=149] @@ -59,6 +59,6 @@ Initial search space (Z): 2 [actual number of targets] Domain search space (domZ): 2 [number of targets reported over threshold] # CPU time: 0.00u 0.00s 00:00:00.00 Elapsed: 00:00:00.00 -# Mc/sec: 18.86 +# Mc/sec: 34.40 // [ok]