Mercurial > repos > iuc > hyphy_fade
annotate hyphy_fade.xml @ 23:17ac281a46d9 draft
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
author | iuc |
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date | Tue, 20 Apr 2021 10:25:54 +0000 |
parents | 7dbcce65a8ff |
children | 5e8d0e777033 |
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0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
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1 <?xml version="1.0"?> |
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7dbcce65a8ff
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit f6cabbd9eb2eea9f5d44fe9836cc5f6d6087a839"
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2 <tool id="hyphy_fade" name="HyPhy-FADE" version="@VERSION@+galaxy0" profile="19.09"> |
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6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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3 <description>: FUBAR* Approach to Directional Evolution (*Fast |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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4 Unconstrained Bayesian Approximation)</description> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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5 <macros> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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6 <import>macros.xml</import> |
23
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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7 <token name="@OPERATION@">FADE</token> |
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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8 <token name="@operation@">fade</token> |
0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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9 </macros> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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10 <expand macro="requirements"/> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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11 <command detect_errors="exit_code"><![CDATA[ |
23
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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12 @SYMLINK_FILES@ |
2
f65e8fe7d5b8
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit f14f2bae2b27dc04e574803c7d4442a64cfe43e4"
iuc
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13 hyphy fade |
23
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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14 --alignment ./$input_file |
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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15 #if $input_nhx: |
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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16 --tree ./input.nhx |
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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17 #end if |
0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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18 --branches '$branches' |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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19 --model '$model' |
5
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
iuc
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20 --method '$posteriorEstimationMethod.method' |
0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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21 --grid '$grid_points' |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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22 --concentration_parameter '$concentration' |
5
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
iuc
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23 @posteriorEstimationMethod_cmd@ |
2
f65e8fe7d5b8
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit f14f2bae2b27dc04e574803c7d4442a64cfe43e4"
iuc
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24 --output '$fade_output' |
23
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
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25 > '$fade_log' ; |
17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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26 @CATCH_ERROR@ |
0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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27 ]]></command> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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28 <inputs> |
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17ac281a46d9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2742ee3b4e90f65352845265d2f85c4263e0eabb"
iuc
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29 <expand macro="inputs"/> |
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6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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30 <expand macro="branches"/> |
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16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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31 <expand macro="substitution"/> |
0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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32 <expand macro="branches"/> |
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16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
iuc
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33 <expand macro="conditional_posteriorEstimationMethod" /> |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
iuc
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34 <param name="grid_points" type="integer" value="20" min="5" max="50" label="Grid points"/> |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
iuc
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35 <param name="concentration" type="float" value="0.5" min="0.001" max="1" label="Concentration parameter of the Dirichlet prior"/> |
0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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36 </inputs> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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37 <outputs> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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38 <data name="fade_log" format="txt"/> |
2
f65e8fe7d5b8
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit f14f2bae2b27dc04e574803c7d4442a64cfe43e4"
iuc
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39 <data name="fade_output" format="hyphy_results.json" /> |
0
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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40 </outputs> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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41 <tests> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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42 <test> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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43 <param name="input_file" ftype="fasta" value="fade-in1.fa"/> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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44 <param name="input_nhx" ftype="nhx" value="fade-in1.nhx"/> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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45 <output name="fade_output" file="fade-out1.json" compare="sim_size"/> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
iuc
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46 </test> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
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47 </tests> |
6164d9298db9
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 2c7a7ff8a55e7584e84335baa3159a63ce7a590c"
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48 <help><![CDATA[ |
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"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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49 |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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50 FADE : FUBAR Approach to Directional Evolution |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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51 ============================================== |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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52 |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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53 What question does this method answer? |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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54 -------------------------------------- |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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55 |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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56 Which site(s) in an alignment evolve towards to or away from a particular residue. |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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57 |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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58 Recommended Applications |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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59 ------------------------ |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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60 |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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61 Screen protein sequence alignments where the direction of evolution can be resolved |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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62 (via tree rooting, e.g. using an outgroup) to find sites which evolve differently from |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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63 a standard protein model (selected by the user), or a gene-average model (GTR) to find |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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64 evidence of directional selection. |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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65 |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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66 Brief description |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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67 ----------------- |
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68 |
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69 FFADE (FUBAR Approach to Directional Evolution) is a fast method to test |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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70 whether or not a subset of sites in a protein alignment evolve towards a |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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71 particular residue along a subset of branches at accelerated rates |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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72 compared to reference model. FADE uses a random effects model and latent |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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73 Dirichlet allocation (LDA) - inspired approximation methods to allocate |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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74 sites to rate classes. |
16b4a3869bd5
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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75 |
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"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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76 Input |
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"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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77 ----- |
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"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 8d5ae1d04c43988fdcc458f4f08376a15e72db8e"
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78 |
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79 1. A *FASTA* sequence alignment of protein sequences. |
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80 2. A *rooted* phylogenetic tree in the *Newick* format |
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81 |
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82 Note: the names of sequences in the alignment must match the names of the sequences in the tree. |
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83 |
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84 |
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85 Output |
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86 ------ |
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87 |
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88 A JSON file with analysis results (http://hyphy.org/resources/json-fields.pdf). |
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89 |
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90 A custom visualization module for viewing these results is available (see http://vision.hyphy.org/FADE for an example) |
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91 |
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92 Further reading |
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93 --------------- |
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94 |
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95 http://hyphy.org/methods/selection-methods/#FADE |
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96 |
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97 |
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98 Tool options |
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99 ------------ |
1
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100 |
5
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101 :: |
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102 |
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103 |
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104 --model The baseline substitution model to use |
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105 [default] use GTR |
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106 |
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107 --branches Which branches should be tested for selection? |
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108 All [default] : test all branches |
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109 |
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110 Internal : test only internal branches (suitable for |
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111 intra-host pathogen evolution for example, where terminal branches |
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112 may contain polymorphism data) |
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113 |
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114 Leaves: test only terminal (leaf) branches |
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115 |
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116 Unlabeled: if the Newick string is labeled using the {} notation, |
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117 test only branches without explicit labels |
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118 (see http://hyphy.org/tutorials/phylotree/) |
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119 |
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120 --grid The number of grid points |
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121 Smaller : faster |
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122 Larger : more precise posterior estimation but slower |
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123 default value: 20 |
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124 |
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125 --method Inference method to use |
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126 Variational-Bayes : 0-th order Variational Bayes approximation; fastest [default] |
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127 Metropolis-Hastings : Full Metropolis-Hastings MCMC algorithm; orignal method [slowest] |
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128 Collapsed-Gibbs : Collapsed Gibbs sampler [intermediate speed] |
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129 |
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130 |
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131 --chains How many MCMC chains to run (does not apply to Variational-Bayes) |
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132 default value: 5 |
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133 |
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134 --chain-length MCMC chain length (does not apply to Variational-Bayes) |
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135 default value: 2,000,000 |
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136 |
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137 --burn-in MCMC chain burn in (does not apply to Variational-Bayes) |
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138 default value: 1,000,000 |
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139 |
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140 --samples MCMC samples to draw (does not apply to Variational-Bayes) |
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141 default value: 1,000 |
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142 |
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143 --concentration_parameter |
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144 The concentration parameter of the Dirichlet prior |
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145 default value: 0.5 |
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146 |
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147 |
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148 |
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149 ]]> |
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150 </help> |
0
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151 <expand macro="citations"> |
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152 </expand> |
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153 </tool> |