Mercurial > repos > iuc > hyphy_prime

annotate hyphy_prime.xml @ 0:725ef5f6d749 draft

Find changesets by keywords (author, files, the commit message), revision number or hash, or revset expression.
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
author iuc
date Fri, 27 Mar 2020 13:15:01 -0400
parents
children 8f66e659530b
Ignore whitespace changes - Everywhere: Within whitespace: At end of lines:
rev   line source
0
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
1 <?xml version="1.0"?>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
2 <tool id="hyphy_prime" name="HyPhy-PRIME" version="@VERSION@+galaxy0">
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
3 <description>Property Informed Models of Evolution</description>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
4 <macros>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
5 <import>macros.xml</import>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
6 </macros>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
7 <expand macro="requirements"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
8 <command detect_errors="exit_code"><![CDATA[
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
9 ln -s '$input_file' prime_input.fa &&
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
10 ln -s '$input_nhx' prime_input.nhx &&
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
11 @HYPHYMPI@ prime
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
12 --alignment ./prime_input.fa
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
13 --tree ./prime_input.nhx
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
14 --code '$gencodeid'
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
15 --branches '$branches'
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
16 --pvalue '$p_value'
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
17 --properties '$prop_set'
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
18 --output '$prime_output'
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
19 > '$prime_log'
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
20 ;
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
21 @CATCH_MPIERR@
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
22 ]]></command>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
23 <inputs>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
24 <expand macro="inputs"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
25 <expand macro="gencode"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
26 <expand macro="branches"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
27 <param name="prop_set" type="select" label="Biochemical properties to use">
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
28 <option value="Atchley">Atchley</option>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
29 <option value="LCAP">LCAP</option>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
30 </param>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
31 <param name="p_value" type="float" value=".1" min="0" max="1" label="P-value threshold"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
32 </inputs>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
33 <outputs>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
34 <data name="prime_log" format="txt"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
35 <data name="prime_output" format="hyphy_results.json" />
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
36 </outputs>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
37 <tests>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
38 <test>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
39 <param name="input_file" ftype="fasta" value="prime-in1.fa"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
40 <param name="input_nhx" ftype="nhx" value="prime-in1.nhx"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
41 <param name="branches" value="All"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
42 <param name="p_value" value="0.1"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
43 <param name="prop_set" value="Atchley"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
44 <output name="prime_output" file="prime-out1.json" compare="sim_size"/>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
45 </test>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
46 </tests>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
47 <help><![CDATA[
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
48 PRIME: Property Informed Model of Evolution
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
49 ===========================================
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
50
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
51 What question does this method answer?
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
52 --------------------------------------
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
53
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
54 Does evolution at specific sites in a coding alignment preserve or alter some biochemical properties?
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
55
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
56 Recommended Applications
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
57 ------------------------
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
58
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
59 Identify biochemical evolutionary constraints or changes with site level resolution: e.g. site 23 is
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
60 evolving to conserve residue polarity, but alter it's volume.
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
61
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
62
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
63 Brief description
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
64 -----------------
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
65
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
66 Most methods of coding sequence analysis do not take direct account of the fact that
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
67 the rate at which amino-acids are exchanged is different depending on the amino-acids.
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
68 While this seems obvious (e.g. radical changes should happen slower), there are many technical reasons
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
69 for why the standard assumption of "one-rate for all residues" holds.
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
70
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
71
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
72 Given a set of N amino-acid properties, fit a site-level model where non-synonymous rates
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
73 depend on how much a non-synonymous substitution changes the properties
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
74 of the residue, beta (X,Y) = Exp (log_omega - lambda_1 * diff_1 (X,Y )-
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
75 lambda_2 * diff_2 (X,Y) -...). When lambda_k > 0, changes in property k
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
76 are disfavored and when lambda_k < 0 -- they are promoted. At each site,
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
77 N+1 tests are performed (one for each property, and an omnibus test).
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
78
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
79 Input
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
80 -----
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
81
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
82 1. A *FASTA* sequence alignment.
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
83 2. A phylogenetic tree in the *Newick* format
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
84
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
85 Note: the names of sequences in the alignment must match the names of the sequences in the tree.
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
86
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
87
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
88 Output
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
89 ------
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
90
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
91 A JSON file with analysis results (http://hyphy.org/resources/json-fields.pdf).
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
92
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
93 A custom visualization module for viewing these results will soon be available at http://vision.hyphy.org/
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
94
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
95 Further reading
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
96 ---------------
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
97
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
98 http://hyphy.org/methods/selection-methods/#PRIME
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
99
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
100
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
101 Tool options
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
102 ------------
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
103 ::
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
104
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
105
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
106 --code Which genetic code to use
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
107
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
108 --branches Which branches should be tested for selection?
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
109 All [default] : test all branches
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
110
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
111 Internal : test only internal branches (suitable for
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
112 intra-host pathogen evolution for example, where terminal branches
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
113 may contain polymorphism data)
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
114
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
115 Leaves: test only terminal (leaf) branches
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
116
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
117 Unlabeled: if the Newick string is labeled using the {} notation,
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
118 test only branches without explicit labels
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
119 (see http://hyphy.org/tutorials/phylotree/)
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
120
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
121 --pvalue The significance level used to determine significance
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
122
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
123 --properties Which property set to use
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
124 Atchley : Use the five properties derived from a factor analysis of 500 amino-acid properties [Table 2 in PNAS (2005) 102(18) 6395-6400 doi: 10.1073/pnas.0408677102]
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
125 LCAP: Use the five properties defined in the Conant and Stadler LCAP model [Mol Biol Evol (2009) 26 (5): 1155-1161. doi: 10.1093/molbev/msp031]
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
126
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
127
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
128 ]]></help>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
129 <!--<expand macro="citations">
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
130 <citation type="doi">10.1371/journal.pgen.1002764</citation>
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
131 </expand>-->
725ef5f6d749 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
iuc
parents:
diff changeset
132 </tool>