# HG changeset patch
# User iuc
# Date 1585329423 14400
# Node ID 6cf8d753e93e064d64f77db0f7b3e23b1b8f084d
# Parent 1cd3060a8504ba11a98c19aa1a14d05b3131aa8d
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/hyphy/ commit 751182d5067ac8378199058d9152ebfcaeb4c4b5"
diff -r 1cd3060a8504 -r 6cf8d753e93e macros.xml
--- a/macros.xml Thu Mar 19 10:16:01 2020 -0400
+++ b/macros.xml Fri Mar 27 13:17:03 2020 -0400
@@ -106,7 +106,7 @@
- 2.5.7
+ 2.5.8
hyphy
@@ -114,6 +114,13 @@
\${GALAXY_MPIRUN:-mpirun -np \${GALAXY_SLOTS:-1}} HYPHYMPI
+ &2 ;
+ fi ;
+ exit \$EC
+ ]]>
HUMAN_VIETNAM_CL105_2005
ATGGAGAAAATAGTGCTTCTTTTTGCGATAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCCCAAGACATACTGGAA
>CHICKEN_HEBEI_326_2005
ATGGAGAGAATAGTGCTTCTTCTTGCAATAATCGGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCTCAAGACATACTGGAG
>CHICKEN_HONGKONG_915_97
ATGGAGAAAATAGTGCTTCTTCTTGCAACAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAATGTTACTGTTACACATGCCCAAGACATACTGGAA
>HUMAN_VIETNAM_3062_2004
ATGGAGAAAATAGTGCTTCTTTTTGCAATAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCCCAAGACATACTGGAA
>GOOSE_HONGKONG_W355_97
ATGGAGAAAATAGTGCTTCTTCTTGCAACAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAATGTTACTGTTACACATGCCCAAGACATACTGGAA
>MALLARD_VIETNAM_16_2003
ATGGAGAAAATAGTGCTTCTTTTTGCAATAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCCCAAGACATACTGGAA
>CHICKEN_CK_160_2005
ATGGAGAAAATAGTGCTTCTTTTTGCAATAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCAACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCCCAAGACATACTGGAA
>CK_HK_WF157_2003
ATGGAGAAAATAGTGCTTCTTCTTGCAATAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCCCAAGACATACTGGAA
>SWINE_ANHUI_1_2004
ATGGAGAAAATAGTGCTTCTTCTTGCAATAGTCAGTCTTGTTAAAGGTGA
TCAGATTTGCACTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCTCAAGACATACTGGAA
>HONGKONG_1_97_98
------------------------------------------------GA
CCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGATA
CAATAATGGAAAAGAATGTTACTGTTACACATGCCCAAGACATACTGGAA
>GOOSE_SHANTOU_2216_2005
ATGGAGAAAATAGTGCTTCTTCTTGCAATAATCAGCCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAACGTTACTGTTACACATGCCCAAGACATACTGGAA
>PEREGRINEFALCON_HK_D0028_2004
ATGGAGAAAATAGTGCTTCTTCTTGCAATAGTCAGTCTTGTTAAAAGTGA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAATGTTACTGTTACACATGCCCAAGACATACTGGAA
>HONGKONG_1_538_97
------------------------------------------------GA
TCAGATTTGCATTGGTTACCATGCAAACAACTCGACAGAGCAGGTTGACA
CAATAATGGAAAAGAATGTTACTGTTACACATGCCCAAGACATACTGGAA
\ No newline at end of file
diff -r 1cd3060a8504 -r 6cf8d753e93e test-data/prime-in1.nhx
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/prime-in1.nhx Fri Mar 27 13:17:03 2020 -0400
@@ -0,0 +1,1 @@
+((((((CHICKEN_HEBEI_326_2005:0.02100885319673648,(SWINE_ANHUI_1_2004:0.007702393698306516):0.002095219592954275):0.003887237703073042):0.003404921392531202,(((CHICKEN_HONGKONG_915_97,(GOOSE_HONGKONG_W355_97):0.002899766890966483):0.001306376767766534,HONGKONG_1_97_98:0.003844928589233716):0.000182535836694054,HONGKONG_1_538_97):0.02096173714686362):0.003130608143291779,(((GOOSE_SHANTOU_2216_2005:0.006207842095177651):0.002530613798219486,PEREGRINEFALCON_HK_D0028_2004:0.003608296348267232):0.003288900909856382,CK_HK_WF157_2003:0.00663129750258774):0.004655295319725731):0.0116808817874948,(((HUMAN_VIETNAM_CL105_2005:0.006521522005742001):0.001967887030302483,HUMAN_VIETNAM_3062_2004:0.001641397323851184):0.0003125512332168847,MALLARD_VIETNAM_16_2003:0.003244216605281072):0.0004125980823087554):0.0003400912533471183,CHICKEN_CK_160_2005:0.006168335080088849)
diff -r 1cd3060a8504 -r 6cf8d753e93e test-data/prime-out1.json
--- /dev/null Thu Jan 01 00:00:00 1970 +0000
+++ b/test-data/prime-out1.json Fri Mar 27 13:17:03 2020 -0400
@@ -0,0 +1,391 @@
+{
+ "MLE":{
+ "content":{
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+ [0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0],
+ [0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0],
+ [0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0],
+ [0, 0, 0, 0, 0, 1, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0, 0, 1, 0],
+ [7.592268336906083, 0, 0.5357744224661302, -5.63867473098278, -5.638674842181149, 1, -0.06122935182163709, 1, -5.638674730981298, -0.06122935182163709, 1, -5.638674730981298, -0.06122935182163709, 1, -5.638674730981298, -0.06122935182163709, 1, -5.638674730981298, -0.06122935182163709, 1, -5.638674730981298]
+ ]
+ },
+ "headers": [
+["alpha;", "Synonymous substitution rate at a site"],
+ ["β", "Log of property independent non-synonymous rate a site"],
+ ["Total branch length", "The total length of branches contributing to inference at this site, and used to scale dN-dS"],
+ ["PRIME LogL", "Site Log-likelihood under the PRIME model"],
+ ["FEL LogL", "Site Log-likelihood under the FEL model"],
+ ["p-value", "Omnibus p-value (any property is important)"],
+ ["λ1", "Importance for Factor I bipolar"],
+ ["p1", "p-value for non-zero effect of Factor I bipolar"],
+ ["LogL1", "Log likelihood when there is no effect of Factor I bipolar"],
+ ["λ2", "Importance for Factor II secondary structure"],
+ ["p2", "p-value for non-zero effect of Factor II secondary structure"],
+ ["LogL2", "Log likelihood when there is no effect of Factor II secondary structure"],
+ ["λ3", "Importance for Factor III volume"],
+ ["p3", "p-value for non-zero effect of Factor III volume"],
+ ["LogL3", "Log likelihood when there is no effect of Factor III volume"],
+ ["λ4", "Importance for Factor IV composition"],
+ ["p4", "p-value for non-zero effect of Factor IV composition"],
+ ["LogL4", "Log likelihood when there is no effect of Factor IV composition"],
+ ["λ5", "Importance for Factor V charge"],
+ ["p5", "p-value for non-zero effect of Factor V charge"],
+ ["LogL5", "Log likelihood when there is no effect of Factor V charge"]
+ ]
+ },
+ "analysis":{
+ "authors":"Sergei L. Kosakovsky Pond",
+ "citation":"TBD",
+ "contact":"spond@temple.edu",
+ "info":"PRIME (PRoperty Informed Model of Evolution). Given a set of N amino-acid properties,\n fit a site-level model where non-synonymous rates depend on how much a non-synonymous substitution changes the \n properties of the residue, beta (X,Y) = Exp (log_omega - lambda_1 * diff_1 (X,Y )- lambda_2 * diff_2 (X,Y) -...).\n When lambda_k > 0, changes in property k are disfavored and when lambda_k < 0 -- they are promoted.\n At each site, N tests are performed\n A subset of branches can be selected\n for testing as well, in which case an additional (nuisance) parameter will be\n inferred -- the non-synonymous rate on branches NOT selected for testing. Multiple partitions within a NEXUS file are also supported\n for recombination - aware analysis.\n ",
+ "requirements":"in-frame codon alignment and a phylogenetic tree",
+ "version":"0.0.1"
+ },
+ "branch attributes":{
+ "0":{
+ "CHICKEN_CK_160_2005":{
+ "Global MG94xREV":0.006875905528136641,
+ "Nucleotide GTR":0.006740765844759078,
+ "original name":"CHICKEN_CK_160_2005"
+ },
+ "CHICKEN_HEBEI_326_2005":{
+ "Global MG94xREV":0.03000509055831138,
+ "Nucleotide GTR":0.02817726192677478,
+ "original name":"CHICKEN_HEBEI_326_2005"
+ },
+ "CHICKEN_HONGKONG_915_97":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0,
+ "original name":"CHICKEN_HONGKONG_915_97"
+ },
+ "CK_HK_WF157_2003":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0,
+ "original name":"CK_HK_WF157_2003"
+ },
+ "GOOSE_HONGKONG_W355_97":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0,
+ "original name":"GOOSE_HONGKONG_W355_97"
+ },
+ "GOOSE_SHANTOU_2216_2005":{
+ "Global MG94xREV":0.008912012248907763,
+ "Nucleotide GTR":0.007985902570718373,
+ "original name":"GOOSE_SHANTOU_2216_2005"
+ },
+ "HONGKONG_1_538_97":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0,
+ "original name":"HONGKONG_1_538_97"
+ },
+ "HONGKONG_1_97_98":{
+ "Global MG94xREV":0.02020234274992877,
+ "Nucleotide GTR":0.02001220163799822,
+ "original name":"HONGKONG_1_97_98"
+ },
+ "HUMAN_VIETNAM_3062_2004":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0,
+ "original name":"HUMAN_VIETNAM_3062_2004"
+ },
+ "HUMAN_VIETNAM_CL105_2005":{
+ "Global MG94xREV":0.006025788919462983,
+ "Nucleotide GTR":0.005802088014335368,
+ "original name":"HUMAN_VIETNAM_CL105_2005"
+ },
+ "MALLARD_VIETNAM_16_2003":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0,
+ "original name":"MALLARD_VIETNAM_16_2003"
+ },
+ "Node10":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node11":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node13":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node17":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node18":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node19":{
+ "Global MG94xREV":0.004922199772633382,
+ "Nucleotide GTR":0.005534464552270369
+ },
+ "Node2":{
+ "Global MG94xREV":0.006872306486383904,
+ "Nucleotide GTR":0.006718147482064949
+ },
+ "Node23":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node24":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node25":{
+ "Global MG94xREV":0.0008268367968756879,
+ "Nucleotide GTR":0.0009189593587976459
+ },
+ "Node3":{
+ "Global MG94xREV":0,
+ "Nucleotide GTR":0
+ },
+ "Node4":{
+ "Global MG94xREV":0.002648185777377607,
+ "Nucleotide GTR":0.00251461257430795
+ },
+ "Node5":{
+ "Global MG94xREV":0.003268514528883674,
+ "Nucleotide GTR":0.003965274251091903
+ },
+ "Node7":{
+ "Global MG94xREV":0.005023432525711092,
+ "Nucleotide GTR":0.004793454999477672
+ },
+ "Node9":{
+ "Global MG94xREV":0.01391813691986412,
+ "Nucleotide GTR":0.01351408611669037
+ },
+ "PEREGRINEFALCON_HK_D0028_2004":{
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+ "original name":"PEREGRINEFALCON_HK_D0028_2004"
+ },
+ "SWINE_ANHUI_1_2004":{
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+ "Nucleotide GTR":0.009150633137551082,
+ "original name":"SWINE_ANHUI_1_2004"
+ }
+ },
+ "attributes":{
+ "Global MG94xREV":{
+ "attribute type":"branch length",
+ "display order":1
+ },
+ "Nucleotide GTR":{
+ "attribute type":"branch length",
+ "display order":0
+ },
+ "original name":{
+ "attribute type":"node label",
+ "display order":-1
+ }
+ }
+ },
+ "data partitions":{
+ "0":{
+ "coverage": [
+[0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49]
+ ],
+ "name":"prime.filter.default"
+ }
+ },
+ "fits":{
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+ [0.006507708080284218],
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+ "Log Likelihood":-277.7176481414617,
+ "Rate Distributions":{
+ "non-synonymous/synonymous rate ratio for *test*": [
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+ },
+ "display order":1,
+ "estimated parameters":43
+ },
+ "Nucleotide GTR":{
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+ "Log Likelihood":-292.5311130078037,
+ "Rate Distributions":{
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+ "Substitution rate from nucleotide A to nucleotide G":1,
+ "Substitution rate from nucleotide A to nucleotide T":0,
+ "Substitution rate from nucleotide C to nucleotide G":0,
+ "Substitution rate from nucleotide C to nucleotide T":1.816257034982832,
+ "Substitution rate from nucleotide G to nucleotide T":0
+ },
+ "display order":0,
+ "estimated parameters":36
+ }
+ },
+ "input":{
+ "file name":"/Users/sergei/Development/tools-iuc/tools/hyphy/test-data/prime-in1.fa",
+ "number of sequences":13,
+ "number of sites":50,
+ "partition count":1,
+ "trees":{
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+ }
+ },
+ "tested":{
+ "0":{
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+ "CHICKEN_HEBEI_326_2005":"test",
+ "CHICKEN_HONGKONG_915_97":"test",
+ "CK_HK_WF157_2003":"test",
+ "GOOSE_HONGKONG_W355_97":"test",
+ "GOOSE_SHANTOU_2216_2005":"test",
+ "HONGKONG_1_538_97":"test",
+ "HONGKONG_1_97_98":"test",
+ "HUMAN_VIETNAM_3062_2004":"test",
+ "HUMAN_VIETNAM_CL105_2005":"test",
+ "MALLARD_VIETNAM_16_2003":"test",
+ "Node10":"test",
+ "Node11":"test",
+ "Node13":"test",
+ "Node17":"test",
+ "Node18":"test",
+ "Node19":"test",
+ "Node2":"test",
+ "Node23":"test",
+ "Node24":"test",
+ "Node25":"test",
+ "Node3":"test",
+ "Node4":"test",
+ "Node5":"test",
+ "Node7":"test",
+ "Node9":"test",
+ "PEREGRINEFALCON_HK_D0028_2004":"test",
+ "SWINE_ANHUI_1_2004":"test"
+ }
+ },
+ "timers":{
+ "Model fitting":{
+ "order":1,
+ "timer":3
+ },
+ "PRIME analysis":{
+ "order":2,
+ "timer":86
+ },
+ "Total time":{
+ "order":0,
+ "timer":89
+ }
+ }
+}
\ No newline at end of file