--- a/iedb_api.py	Sat Feb 13 00:06:36 2021 +0000
+++ b/iedb_api.py	Fri Nov 07 18:26:22 2025 +0000
@@ -250,7 +250,7 @@
     length = ','.join(lengths) if lengths else None
     method = args.method
     proteasome = args.proteasome if args.prediction == 'processcing' else None
-    url = 'http://tools-cluster-interface.iedb.org/tools_api/%s/' %\
+    url = 'https://tools-cluster-interface.iedb.org/tools_api/%s/' %\
         args.prediction
 
     # results

--- a/iedb_api.xml	Sat Feb 13 00:06:36 2021 +0000
+++ b/iedb_api.xml	Fri Nov 07 18:26:22 2025 +0000
@@ -1,6 +1,9 @@
-<tool id="iedb_api" name="IEDB" version="2.15.2">
+<tool id="iedb_api" name="IEDB" version="@TOOL_VERSION@+galaxy@VERSION_SUFFIX@" profile="@PROFILE@">
     <description>MHC Binding prediction</description>
     <macros>
+        <token name="@TOOL_VERSION@">2.15.3</token>
+        <token name="@VERSION_SUFFIX@">0</token>
+        <token name="@PROFILE@">24.2</token>
         <xml name="alleles" token_hla_regex="" token_hla_examples="" token_hlalen_examples=""> 
             <conditional name="alleles">
                <param name="allelesrc" type="select" label="Alleles">
@@ -129,7 +132,7 @@
                     <option value="comblib">comblib</option>
                     <option value="tepitope">tepitope</option>
                 </param>
-                <expand macro="alleles" hla_regex="(DPA1\*0[1-3](:0[1-3])?/DPB1\*0[1-6]:0[12]|DQA1\*0[1-5]:0[12]/DQB1\*0[2-6]:0[12]|(HLA-)?DRB[1-5]\*[01][1-9]:0[1-5]|H2-IA[bd])(,(asis|[1-2][0-9]|30))*" hla_examples="DPA1*01/DPB1*04:01 HLA-DRB1*01:01 H2-IAb" hlalen_examples="DPA1*01/DPB1*04:01,11,15"/>
+                <expand macro="alleles" hla_regex="(DPA1\*0[1-3]:0[1-3]/DPB1\*0[1-6]:0[12]|DQA1\*0[1-5]:0[12]/DQB1\*0[2-6]:0[12]|(HLA-)?DRB[1-5]\*[01][1-9]:0[1-5]|H2-IA[bd])(,(asis|[1-2][0-9]|30))*" hla_examples="DPA1*01:03/DPB1*04:01 HLA-DRB1*01:01 H2-IAb" hlalen_examples="DPA1*01:03/DPB1*04:01,11,15"/>
                 <param name="lengths" type="select" multiple="true" optional="false" label="peptide lengths for prediction">
                     <help>Used for any alleles which don't include specified lengths</help>
                     <option value="asis">asis</option>
@@ -309,7 +312,7 @@
                 <param name="method" value="recommended"/>
                 <conditional name="alleles">
                     <param name="allelesrc" value="entry"/>
-                    <param name="allele_text" value="DPA1*01/DPB1*04:01"/>
+                    <param name="allele_text" value="DPA1*01:03/DPB1*04:01"/>
                 </conditional>
                 <param name="lengths" value="asis"/>
             </conditional>
@@ -319,7 +322,7 @@
             </conditional>
             <output name="output">
                 <assert_contents>
-                    <has_text text="LYNTVATLY" />
+                    <has_text text="VATLYCVHQ" />
                 </assert_contents>
             </output>
         </test>
@@ -403,7 +406,7 @@
 The IEDB is a free resource, funded by a contract from the National Institute of Allergy and Infectious Diseases. It offers easy searching of experimental data characterizing antibody and T cell epitopes studied in humans, non-human primates, and other animal species. 
 
 This tool retrieves epitope binding information about input peptide sequences by using the RESTful web services provided by IEDB.  
-The webservices are described at:  http://tools.immuneepitope.org/main/tools-api/
+The webservices are described at:  https://tools.iedb.org/main/tools-api/
 That page also describes how to retrieve the available HLA alleles for class of epitope binding.
 
 **INPUTS**