- 4.12.0
+ 5.0.5
- graphicsmagick
- meme
+ meme
diff -r c1a9a297ba8b -r 0c5239d1aa65 test-data/dreme_output_test1.html
--- a/test-data/dreme_output_test1.html Wed Dec 12 02:50:48 2018 -0500
+++ b/test-data/dreme_output_test1.html Wed Dec 11 18:05:35 2019 -0500
@@ -7,10 +7,9 @@
// @JSON_VAR data
var data = {
"program": "dreme",
- "version": "4.12.0",
- "release": "Tue Jun 27 16:22:50 2017 -0700",
+ "version": "5.0.5",
"cmd": [
- "dreme", "-o", "./dreme_test1_out", "-p", "dreme_test_sites.fa",
+ "dreme", "-o", "./dreme_out", "-p",
"-norc", "-rna", "-s", "1"
],
"options": {
@@ -20,95 +19,19 @@
"seed": 1,
"stop": {
"evalue": "0.05"
- }
- },
"alphabet": {
"name": "RNA",
"like": "rna",
"ncore": 4,
"symbols": [
- {
- "symbol": "A",
- "name": "Adenine",
- "colour": "CC0000"
- }, {
- "symbol": "C",
- "name": "Cytosine",
- "colour": "0000CC"
- }, {
- "symbol": "G",
- "name": "Guanine",
- "colour": "FFB300"
- }, {
- "symbol": "U",
- "aliases": "T",
- "name": "Uracil",
- "colour": "008000"
- }, {
- "symbol": "N",
- "aliases": "X.",
- "name": "Any base",
- "equals": "ACGU"
- }, {
- "symbol": "V",
- "name": "Not U",
- "equals": "ACG"
- }, {
- "symbol": "H",
- "name": "Not G",
- "equals": "ACU"
- }, {
- "symbol": "D",
- "name": "Not C",
- "equals": "AGU"
- }, {
- "symbol": "B",
- "name": "Not A",
- "equals": "CGU"
- }, {
- "symbol": "M",
- "name": "Amino",
- "equals": "AC"
- }, {
- "symbol": "R",
- "name": "Purine",
- "equals": "AG"
- }, {
- "symbol": "W",
- "name": "Weak",
- "equals": "AU"
- }, {
- "symbol": "S",
- "name": "Strong",
- "equals": "CG"
- }, {
- "symbol": "Y",
- "name": "Pyrimidine",
- "equals": "CU"
- }, {
- "symbol": "K",
- "name": "Keto",
- "equals": "GU"
- }
- ]
- },
"background": {
"freqs": [0.221, 0.245, 0.221, 0.312]
- },
- "sequence_db": {
- "name": "dreme test sites",
- "file": "dreme_test_sites.fa",
- "lmod": "Thu Apr 26 15:09:03 CEST 2018",
- "count": 1000
- },
"control_db": {
"name": "shuffled positive sequences",
"from": "shuffled",
"count": 1000,
"freqs": [0.221, 0.245, 0.221, 0.312]
- },
"motifs": [
- {
"db": 0,
"id": "UUYUCY",
"alt": "DREME-1",
@@ -126,9 +49,7 @@
[0.000000, 0.000000, 0.000000, 1.000000],
[0.000000, 1.000000, 0.000000, 0.000000],
[0.000000, 0.474946, 0.000000, 0.525054]
- ],
"matches": [
- {
"seq": "UUUUCC",
"p": 147,
"n": 75,
@@ -140,6059 +61,53 @@
"n": 94,
"pvalue": "2.2e-005",
"evalue": "1.0e+000"
- }, {
"seq": "UUCUCU",
"p": 94,
"n": 51,
"pvalue": "1.3e-004",
"evalue": "6.1e+000"
- }, {
"seq": "UUCUCC",
"p": 75,
"n": 42,
"pvalue": "1.1e-003",
"evalue": "5.0e+001"
- }
- ]
- }, {
- "db": 0,
- "id": "YAGG",
- "alt": "DREME-2",
- "len": 4,
- "nsites": 793,
- "evalue": "5.1e-012",
- "p": 600,
- "n": 416,
- "pvalue": "1.1e-016",
- "unerased_evalue": "2.4e-012",
- "pwm": [
- [0.000000, 0.692308, 0.000000, 0.307692],
- [1.000000, 0.000000, 0.000000, 0.000000],
- [0.000000, 0.000000, 1.000000, 0.000000],
- [0.000000, 0.000000, 1.000000, 0.000000]
- ],
- "matches": [
- {
- "seq": "CAGG",
- "p": 441,
- "n": 304,
- "pvalue": "1.5e-010",
- "evalue": "6.6e-006"
- }, {
- "seq": "UAGG",
- "p": 232,
- "n": 165,
- "pvalue": "1.1e-004",
- "evalue": "4.7e+000"
- }
- ]
- }, {
- "db": 0,
- "id": "GAAGAW",
- "alt": "DREME-3",
- "len": 6,
- "nsites": 89,
- "evalue": "3.4e-005",
- "p": 81,
- "n": 22,
- "pvalue": "8.2e-010",
- "unerased_evalue": "3.5e-004",
- "pwm": [
- [0.000000, 0.000000, 1.000000, 0.000000],
- [1.000000, 0.000000, 0.000000, 0.000000],
- [1.000000, 0.000000, 0.000000, 0.000000],
- [0.000000, 0.000000, 1.000000, 0.000000],
- [1.000000, 0.000000, 0.000000, 0.000000],
- [0.494382, 0.000000, 0.000000, 0.505618]
- ],
- "matches": [
- {
- "seq": "GAAGAU",
- "p": 45,
- "n": 7,
- "pvalue": "2.4e-008",
- "evalue": "9.9e-004"
- }, {
- "seq": "GAAGAA",
- "p": 40,
- "n": 16,
- "pvalue": "7.9e-004",
- "evalue": "3.3e+001"
- }
- ]
- }, {
- "db": 0,
- "id": "SMUGGA",
- "alt": "DREME-4",
- "len": 6,
- "nsites": 119,
- "evalue": "3.7e-003",
- "p": 110,
- "n": 47,
- "pvalue": "9.1e-008",
- "unerased_evalue": "2.6e-005",
- "pwm": [
- [0.000000, 0.529412, 0.470588, 0.000000],
- [0.428571, 0.571429, 0.000000, 0.000000],
- [0.000000, 0.000000, 0.000000, 1.000000],
- [0.000000, 0.000000, 1.000000, 0.000000],
- [0.000000, 0.000000, 1.000000, 0.000000],
- [1.000000, 0.000000, 0.000000, 0.000000]
- ],
- "matches": [
- {
- "seq": "GAUGGA",
- "p": 22,
- "n": 6,
- "pvalue": "1.7e-003",
- "evalue": "7.1e+001"
- }, {
- "seq": "GCUGGA",
- "p": 33,
- "n": 14,
- "pvalue": "3.6e-003",
- "evalue": "1.5e+002"
- }, {
- "seq": "CCUGGA",
- "p": 32,
- "n": 15,
- "pvalue": "8.6e-003",
- "evalue": "3.5e+002"
- }, {
- "seq": "CAUGGA",
- "p": 29,
- "n": 13,
- "pvalue": "9.1e-003",
- "evalue": "3.7e+002"
- }
- ]
- }
- ],
- "runtime": {
- "host": "ThinkPad-T450s",
- "when": "Thu May 03 13:22:29 CEST 2018",
- "cpu": 13.95,
- "real": 13.95,
- "stop": "evalue"
- }
- };
-
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The name of the motif uses the IUPAC codes for nucleotides which has
a different letter to represent each of the 15 possible combinations.
-
-
The name is itself a representation of the motif though the position
- weight matrix is not directly equalivant as it is generated from the
+ weight matrix is not directly equivalent as it is generated from the
sites found that matched the letters given in the name.
-
-
-
- Read more about the MEME suite's use of the IUPAC alphabets.
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The logo of the motif.
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The logo of the reverse complement motif.
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-
The E-value is the enrichment p-value times the number of candidate
motifs tested.
The enrichment p-value is calculated using Fisher's Exact Test for
enrichment of the motif in the positive sequences.
Note that the counts used in Fisher's Exact Test are made after
erasing sites that match previously found motifs.
-
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-
The E-value of the motif calculated without erasing the sites of
previously found motifs.
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Show more information on the motif.
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-
Submit your motif to another MEME Suite program or download your motif.
Supported Programs
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Tomtom
Tomtom is a tool for searching for similar known motifs.
-
MAST
MAST is a tool for searching biological sequence databases for
sequences that contain one or more of a group of known motifs.
-
FIMO
FIMO is a tool for searching biological sequence databases for
sequences that contain one or more known motifs.
-
- GOMO
- GOMO is a tool for identifying possible roles (Gene Ontology
+ GOMo
+ GOMo is a tool for identifying possible roles (Gene Ontology
terms) for DNA binding motifs.
-
SpaMo
SpaMo is a tool for inferring possible transcription factor
complexes by finding motifs with enriched spacings.
-
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# positive sequences matching the motif / # positive sequences.
-
Note these counts are made after erasing sites that match previously
- found motifs.
-
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# negative sequences matching the motif / # negative sequences.
-
Note these counts are made after erasing sites that match previously
- found motifs.
-
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-
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The p-value of Fisher's Exact Test for enrichment of the motif in
- the positive sequences.
-
Note that the counts used in Fisher's Exact Test are made after
- erasing sites that match previously found motifs.
-
-
-
-
The E-value is the motif p-value times the number of candidate motifs
- tested.
-
Note that the p-value was calculated with counts made after
- erasing sites that match previously found motifs.
-
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-
The E-value of the motif calculated without erasing the sites of
- previously found motifs.
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All words matching the motif whose uncorrected p-value is less than
- .
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# positive sequences with matches to the word / # positive sequences.
-
Note these counts are made after erasing sites that match previously
- found motifs.
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# negative sequences with matches to the word / # negative sequences.
-
Note these counts are made after erasing sites that match previously
- found motifs.
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The p-value of Fisher's Exact Test for enrichment of the word in
- the positive sequences.
-
Note that the counts used in Fisher's Exact Test are made after
- erasing sites that match previously found motifs.
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The word p-value times the number of candidates tested.
-
Note that the p-value was calculated with counts made after
- erasing sites that match previously found motifs.
-
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The sequence file used by DREME to find the motifs.
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The alphabet of the sequences.
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The count of the sequences.
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The name of the alphabet symbol.
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The frequency of the alphabet symbol in the control dataset.
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Details
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- Positives
- Negatives
- P-value
- E-value
- Unerased E-value
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- /
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Enriched Matching Words
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DREME
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Discriminative Regular Expression Motif Elicitation
-
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- For further information on how to interpret these results or to get a
- copy of the MEME software please access
- http://meme.nbcr.net .
-
-
- If you use DREME in your research please cite the following paper:
-
- Timothy L. Bailey, "DREME: Motif discovery in transcription factor ChIP-seq data", Bioinformatics , 27 (12):1653-1659, 2011.
- [full text]
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- Javascript is required to view these results!
- Your browser does not support canvas!
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No motifs were discovered!
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Sequences
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Control Sequences
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Background
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Other Settings
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DREME version
-
- (Release date: )
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Reference
-
- Timothy L. Bailey, "DREME: Motif discovery in transcription factor ChIP-seq data", Bioinformatics , 27 (12):1653-1659, 2011.
- [full text]
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Command line
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