Mercurial > repos > iuc > nanocompore_sampcomp
changeset 0:557cf45ff2c8 draft
"planemo upload for repository https://github.com/galaxyproject/tools-iuc/tree/master/tools/nanocompore commit 8fa5ff35b45c2b046c7f4800410cf39cb89a299a"
author | iuc |
---|---|
date | Tue, 05 May 2020 06:57:10 -0400 |
parents | |
children | c43f4b80f5a9 |
files | macros.xml sampcomp.xml test-data/reference.fa test-data/sample1.tsv test-data/sample1.tsv.idx test-data/sample2.tsv test-data/sample2.tsv.idx |
diffstat | 7 files changed, 1466 insertions(+), 0 deletions(-) [+] |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/macros.xml Tue May 05 06:57:10 2020 -0400 @@ -0,0 +1,31 @@ +<?xml version="1.0"?> +<macros> + <token name="@TOOL_VERSION@">1.0.0rc3.post2</token> + <token name="@WRAPPER_VERSION@">galaxy0</token> + <token name="@DESCRIPTION@"></token> + <xml name="requirements"> + <requirements> + <requirement type="package" version="@TOOL_VERSION@">nanocompore</requirement> + </requirements> + </xml> + <xml name="citations"> + <citations> + <citation type="bibtex">@online{Nanocompore, + author = {Adrien Leger, Tommaso Leonard}, + title = {Nanocompore}, + year = 2019, + url = {https://nanocompore.rna.rocks/}, + urldate = {2020-04-30} + }</citation> + </citations> + </xml> + <token name="@WID@"><![CDATA[ +Nanocompore identifies differences in ONT nanopore sequencing raw signal corresponding to RNA modifications by comparing 2 samples + +Nanocompore compares 2 ONT nanopore direct RNA sequencing datasets from different experimental conditions expected to have a significant impact on RNA modifications. It is recommended to have at least 2 replicates per condition. For example one can use a control condition with a significantly reduced number of modifications such as a cell line for which a modification writing enzyme was knocked-down or knocked-out. Alternatively, on a smaller scale transcripts of interests could be synthesized in-vitro. + ]]></token> + + <token name="@REFERENCES@"><![CDATA[ +More information are available on the `project website <https://nanocompore.rna.rocks/>`_ and `github <https://github.com/tleonardi/nanocompore>`_. + ]]></token> +</macros> \ No newline at end of file
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/sampcomp.xml Tue May 05 06:57:10 2020 -0400 @@ -0,0 +1,220 @@ +<?xml version="1.0"?> +<tool id="nanocompore_sampcomp" name="SampComp" version="@TOOL_VERSION@+@WRAPPER_VERSION@"> + <description>to compare Nanopolished datasets</description> + <macros> + <import>macros.xml</import> + </macros> + <expand macro="requirements"/> + <version_command><![CDATA[nanocompore --version]]></version_command> + <command detect_errors="exit_code"><![CDATA[ + ## initialize + ## requires a minimum of 3 threads + threads=\$((3 > \${GALAXY_SLOTS:-3} ? 3 : \${GALAXY_SLOTS:-3})) && + ## same name pattern required + #for $i, $current in enumerate($file1_rep) + ln -s '$current.file' 'sample_1_${i}.tsv' && + ln -s '$current.index' 'sample_1_${i}.tsv.idx' && + #end for + #for $i, $current in enumerate($file2_rep) + ln -s '$current.file' 'sample_2_${i}.tsv' && + ln -s '$current.index' 'sample_2_${i}.tsv.idx' && + #end for + + ## run + nanocompore sampcomp + ## required + --label1 '$label1' + #set files1 = ','.join(['sample_1_' + str(item) + '.tsv' for item in range(len($file1_rep))]) + --file_list1 '$files1' + --label2 '$label2' + #set files2 = ','.join(['sample_2_' + str(item) + '.tsv' for item in range(len($file2_rep))]) + --file_list2 '$files2' + --fasta '$fasta' + ## optional + #if $ap.bed + --bed '$ap.bed' + #end if + --max_invalid_kmers_freq $ap.max_invalid_kmers_freq + --min_coverage $ap.min_coverage + --min_ref_length $ap.min_ref_length + --comparison_methods '$ap.comparison_methods' + --sequence_context $ap.sequence_context + --sequence_context_weights '$ap.sequence_context_weights' + --pvalue_thr $ap.pvalue_thr + $ap.logit + $ap.allow_warnings + --outpath 'results' + --nthreads \$threads + --log_level debug + + && tar -cf 'results/db.tar' 'results/out_SampComp.db.bak' 'results/out_SampComp.db.dir' 'results/out_SampComp.db.dat' + ]]></command> + <inputs> + <param argument="--label1" type="text" value="Condition 1" label="Set label of first condition"/> + <repeat name="file1_rep" min="1" title="First condition files"> + <param name="file" type="data" format="tabular" label="Select NanopolishComp file" help="(--file_list1)"/> + <param name="index" type="data" format="tabular" label="Select index file"/> + </repeat> + <param argument="--label2" type="text" value="Condition 2" label="Set label of second condition"/> + <repeat name="file2_rep" min="1" title="Second condition files"> + <param name="file" type="data" format="tabular" label="Select NanopolishComp file" help="(--file_list2)"/> + <param name="index" type="data" format="tabular" label="Select index file"/> + </repeat> + <param argument="--fasta" type="data" format="fasta" label="Select mapping file"/> + + <section name="ap" title="Advanced parameters"> + <param argument="--bed" type="data" format="bed" optional="true" label="Select mapping file with annotation of transcriptome"/> + <param argument="--max_invalid_kmers_freq" type="float" value="0.1" min="0.0" max="1.0" label="Set max fequency of invalid kmers"/> + <param argument="--min_coverage" type="integer" value="30" min="0" label="Set minimum coverage required in each condition to do the comparison"/> + <param argument="--min_ref_length" type="integer" value="100" min="0" label="Set minimum length of a reference transcript to include it in the analysis"/> + <param argument="--comparison_methods" type="select" multiple="true" label="Select comparison methods"> + <option value="GMM" selected="true">GMM</option> + <option value="KS" selected="true">KS</option> + <option value="TT">TT</option> + <option value="MW">MW</option> + </param> + <param argument="--sequence_context" type="integer" value="0" min="0" max="4" label="Set sequence context for combining p-values"/> + <param argument="--sequence_context_weights" type="select" label="Select type of weights to use for combining p-values"> + <option value="uniform" selected="true">Uniform</option> + <option value="harmonic">Harmonic</option> + </param> + <param argument="--pvalue_thr" type="float" value="0.05" min="0.0" max="1.0" label="Set adjusted p-value threshold for reporting significant sites"/> + <param argument="--logit" type="boolean" truevalue="--logit" falsevalue="" label="Use logistic regression testing also when all conditions have replicates?"/> + <param argument="--allow_warnings" type="boolean" truevalue="--allow_warnings" falsevalue="" label="Should runtime warnings during the ANOVA tests raise an error?"/> + <param name="out" type="select" multiple="true" optional="false" label="Select output file(s)"> + <option value="results" selected="true">Results</option> + <option value="shift" selected="true">Shift stats</option> + <option value="db" selected="true">Database (*.db.dir, *.db.bak, *.db.dat)</option> + <option value="log">Log</option> + </param> + </section> + </inputs> + <outputs> + <data name="out_results" format="tabular" from_work_dir="results/out_nanocompore_results.tsv" label="${tool.name} on ${on_string}: Results"> + <filter>'results' in ap['out']</filter> + </data> + <data name="out_shift" format="tabular" from_work_dir="results/out_nanocompore_shift_stats.tsv" label="${tool.name} on ${on_string}: Shift stats"> + <filter>'shift' in ap['out']</filter> + </data> + <data name="out_db" format="tar" from_work_dir="results/db.tar" label="${tool.name} on ${on_string}: Database"> + <filter>'db' in ap['out']</filter> + </data> + <data name="out_log" format="txt" from_work_dir="results/out_SampComp.log" label="${tool.name} on ${on_string}: log"> + <filter>'log' in ap['out']</filter> + </data> + </outputs> + <tests> + <!-- #1 --> + <test expect_num_outputs="3"> + <repeat name="file1_rep"> + <param name="file" value="sample1.tsv"/> + <param name="index" value="sample1.tsv.idx"/> + </repeat> + <repeat name="file2_rep"> + <param name="file" value="sample2.tsv"/> + <param name="index" value="sample2.tsv.idx"/> + </repeat> + <param name="fasta" value="reference.fa"/> + <output name="out_results"> + <assert_contents> + <has_n_lines n="3"/> + <has_text_matching expression="pos	chr.+"/> + <has_text_matching expression="22102	NA.+"/> + </assert_contents> + </output> + <output name="out_shift"> + <assert_contents> + <has_n_lines n="3"/> + <has_text_matching expression="ref\_id	pos.+"/> + <has_text_matching expression="chr	22102.+"/> + </assert_contents> + </output> + <output name="out_db"> + <assert_contents> + <has_size value="5408256"/> + </assert_contents> + </output> + </test> + <!-- #2 --> + <test expect_num_outputs="4"> + <param name="label1" value="C1"/> + <repeat name="file1_rep"> + <param name="file" value="sample1.tsv"/> + <param name="index" value="sample1.tsv.idx"/> + </repeat> + <param name="label2" value="C2"/> + <repeat name="file2_rep"> + <param name="file" value="sample2.tsv"/> + <param name="index" value="sample2.tsv.idx"/> + </repeat> + <param name="fasta" value="reference.fa"/> + <section name="ap"> + <param name="max_invalid_kmers_freq" value="0.2"/> + <param name="min_coverage" value="31"/> + <param name="min_ref_length" value="101"/> + <param name="comparison_methods" value="GMM,KS,TT,MW"/> + <param name="sequence_context" value="1"/> + <param name="sequence_context_weights" value="harmonic"/> + <param name="pvalue_thr" value="0.06"/> + <param name="logit" value="true"/> + <param name="allow_warnings" value="true"/> + <param name="out" value="results,shift,db,log"/> + </section> + <output name="out_results"> + <assert_contents> + <has_n_lines n="3"/> + <has_text_matching expression="pos	chr.+"/> + <has_text_matching expression="22102	NA.+"/> + </assert_contents> + </output> + <output name="out_shift"> + <assert_contents> + <has_n_lines n="3"/> + <has_text_matching expression="ref\_id	pos.+"/> + <has_text_matching expression="chr	22102.+"/> + </assert_contents> + </output> + <output name="out_db"> + <assert_contents> + <has_size value="5410304"/> + </assert_contents> + </output> + <output name="out_log"> + <assert_contents> + <has_n_lines n="31"/> + <has_text_matching expression=".+package\_name.+"/> + </assert_contents> + </output> + </test> + </tests> + <help><![CDATA[ +.. class:: infomark + +**What it does** + +@WID@ + +SampComp provides a very flexible analysis framework with a few mandatory options and many optional parameters. + +First, SampComp parses the sample eventalign collapse files and then the observed results are piled-up per reference at position level. In a second time, positions are compared using various statistical methods and the statistics are stored in a shelve DBM database containing the results for all positions with sufficient coverage. + +**Input** + +SampComp requires sample files obtained with NanopolishComp EventalignCollapse as explained before (see data preparation) for both the control and the experimental conditions. 2 conditions are expected and at least 2 replicates per conditions are highly recommended. + +A transcriptome FASTA reference file is required to extract kmer sequences during the analyses. The reference has to be the same as the one used at the mapping step. + +Optionally, a BED file containing the genome annotations corresponding to the transcriptome fasta file can be provided. In that case Nanocompore will also convert the transcript coordinates into the genome space. + +**Output** + +The database object returned by Sampcomp is a Python GDBM object database indexed by reference id and can be be used with SampCompDB. + +.. class:: infomark + +**References** + +@REFERENCES@ + ]]></help> + <expand macro="citations"/> +</tool> \ No newline at end of file
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/reference.fa Tue May 05 06:57:10 2020 -0400 @@ -0,0 +1,417 @@ +>chr +ATTAAAGGTTTATACCTTCCCAGGTAACAAACCAACCAACTTTCGATCTCTTGTAGATCTGTTCTCTAAACG +AACTTTAAAATCTGTGTGGCTGTCACTCGGCTGCATGCTTAGTGCACTCACGCAGTATAATTAATAACTAAT +TACTGTCGTTGACAGGACACGAGTAACTCGTCTATCTTCTGCAGGCTGCTTACGGTTTCGTCCGTGTTGCAG +CCGATCATCAGCACATCTAGGTTTCGTCCGGGTGTGACCGAAAGGTAAGATGGAGAGCCTTGTCCCTGGTTT +CAACGAGAAAACACACGTCCAACTCAGTTTGCCTGTTTTACAGGTTCGCGACGTGCTCGTACGTGGCTTTGG +AGACTCCGTGGAGGAGGTCTTATCAGAGGCACGTCAACATCTTAAAGATGGCACTTGTGGCTTAGTAGAAGT +TGAAAAAGGCGTTTTGCCTCAACTTGAACAGCCCTATGTGTTCATCAAACGTTCGGATGCTCGAACTGCACC +TCATGGTCATGTTATGGTTGAGCTGGTAGCAGAACTCGAAGGCATTCAGTACGGTCGTAGTGGTGAGACACT +TGGTGTCCTTGTCCCTCATGTGGGCGAAATACCAGTGGCTTACCGCAAGGTTCTTCTTCGTAAGAACGGTAA +TAAAGGAGCTGGTGGCCATAGTTACGGCGCCGATCTAAAGTCATTTGACTTAGGCGACGAGCTTGGCACTGA +TCCTTATGAAGATTTTCAAGAAAACTGGAACACTAAACATAGCAGTGGTGTTACCCGTGAACTCATGCGTGA +GCTTAACGGAGGGGCATACACTCGCTATGTCGATAACAACTTCTGTGGCCCTGATGGCTACCCTCTTGAGTG +CATTAAAGACCTTCTAGCACGTGCTGGTAAAGCTTCATGCACTTTGTCCGAACAACTGGACTTTATTGACAC +TAAGAGGGGTGTATACTGCTGCCGTGAACATGAGCATGAAATTGCTTGGTACACGGAACGTTCTGAAAAGAG +CTATGAATTGCAGACACCTTTTGAAATTAAATTGGCAAAGAAATTTGACACCTTCAATGGGGAATGTCCAAA +TTTTGTATTTCCCTTAAATTCCATAATCAAGACTATTCAACCAAGGGTTGAAAAGAAAAAGCTTGATGGCTT +TATGGGTAGAATTCGATCTGTCTATCCAGTTGCGTCACCAAATGAATGCAACCAAATGTGCCTTTCAACTCT +CATGAAGTGTGATCATTGTGGTGAAACTTCATGGCAGACGGGCGATTTTGTTAAAGCCACTTGCGAATTTTG +TGGCACTGAGAATTTGACTAAAGAAGGTGCCACTACTTGTGGTTACTTACCCCAAAATGCTGTTGTTAAAAT +TTATTGTCCAGCATGTCACAATTCAGAAGTAGGACCTGAGCATAGTCTTGCCGAATACCATAATGAATCTGG +CTTGAAAACCATTCTTCGTAAGGGTGGTCGCACTATTGCCTTTGGAGGCTGTGTGTTCTCTTATGTTGGTTG +CCATAACAAGTGTGCCTATTGGGTTCCACGTGCTAGCGCTAACATAGGTTGTAACCATACAGGTGTTGTTGG +AGAAGGTTCCGAAGGTCTTAATGACAACCTTCTTGAAATACTCCAAAAAGAGAAAGTCAACATCAATATTGT +TGGTGACTTTAAACTTAATGAAGAGATCGCCATTATTTTGGCATCTTTTTCTGCTTCCACAAGTGCTTTTGT +GGAAACTGTGAAAGGTTTGGATTATAAAGCATTCAAACAAATTGTTGAATCCTGTGGTAATTTTAAAGTTAC +AAAAGGAAAAGCTAAAAAAGGTGCCTGGAATATTGGTGAACAGAAATCAATACTGAGTCCTCTTTATGCATT +TGCATCAGAGGCTGCTCGTGTTGTACGATCAATTTTCTCCCGCACTCTTGAAACTGCTCAAAATTCTGTGCG +TGTTTTACAGAAGGCCGCTATAACAATACTAGATGGAATTTCACAGTATTCACTGAGACTCATTGATGCTAT +GATGTTCACATCTGATTTGGCTACTAACAATCTAGTTGTAATGGCCTACATTACAGGTGGTGTTGTTCAGTT +GACTTCGCAGTGGCTAACTAACATCTTTGGCACTGTTTATGAAAAACTCAAACCCGTCCTTGATTGGCTTGA +AGAGAAGTTTAAGGAAGGTGTAGAGTTTCTTAGAGACGGTTGGGAAATTGTTAAATTTATCTCAACCTGTGC +TTGTGAAATTGTCGGTGGACAAATTGTCACCTGTGCAAAGGAAATTAAGGAGAGTGTTCAGACATTCTTTAA +GCTTGTAAATAAATTTTTGGCTTTGTGTGCTGACTCTATCATTATTGGTGGAGCTAAACTTAAAGCCTTGAA +TTTAGGTGAAACATTTGTCACGCACTCAAAGGGATTGTACAGAAAGTGTGTTAAATCCAGAGAAGAAACTGG +CCTACTCATGCCTCTAAAAGCCCCAAAAGAAATTATCTTCTTAGAGGGAGAAACACTTCCCACAGAAGTGTT +AACAGAGGAAGTTGTCTTGAAAACTGGTGATTTACAACCATTAGAACAACCTACTAGTGAAGCTGTTGAAGC +TCCATTGGTTGGTACACCAGTTTGTATTAACGGGCTTATGTTGCTCGAAATCAAAGACACAGAAAAGTACTG +TGCCCTTGCACCTAATATGATGGTAACAAACAATACCTTCACACTCAAAGGCGGTGCACCAACAAAGGTTAC +TTTTGGTGATGACACTGTGATAGAAGTGCAAGGTTACAAGAGTGTGAATATCACTTTTGAACTTGATGAAAG +GATTGATAAAGTACTTAATGAGAAGTGCTCTGCCTATACAGTTGAACTCGGTACAGAAGTAAATGAGTTCGC +CTGTGTTGTGGCAGATGCTGTCATAAAAACTTTGCAACCAGTATCTGAATTACTTACACCACTGGGCATTGA +TTTAGATGAGTGGAGTATGGCTACATACTACTTATTTGATGAGTCTGGTGAGTTTAAATTGGCTTCACATAT +GTATTGTTCTTTCTACCCTCCAGATGAGGATGAAGAAGAAGGTGATTGTGAAGAAGAAGAGTTTGAGCCATC +AACTCAATATGAGTATGGTACTGAAGATGATTACCAAGGTAAACCTTTGGAATTTGGTGCCACTTCTGCTGC +TCTTCAACCTGAAGAAGAGCAAGAAGAAGATTGGTTAGATGATGATAGTCAACAAACTGTTGGTCAACAAGA +CGGCAGTGAGGACAATCAGACAACTACTATTCAAACAATTGTTGAGGTTCAACCTCAATTAGAGATGGAACT +TACACCAGTTGTTCAGACTATTGAAGTGAATAGTTTTAGTGGTTATTTAAAACTTACTGACAATGTATACAT +TAAAAATGCAGACATTGTGGAAGAAGCTAAAAAGGTAAAACCAACAGTGGTTGTTAATGCAGCCAATGTTTA +CCTTAAACATGGAGGAGGTGTTGCAGGAGCCTTAAATAAGGCTACTAACAATGCCATGCAAGTTGAATCTGA +TGATTACATAGCTACTAATGGACCACTTAAAGTGGGTGGTAGTTGTGTTTTAAGCGGACACAATCTTGCTAA +ACACTGTCTTCATGTTGTCGGCCCAAATGTTAACAAAGGTGAAGACATTCAACTTCTTAAGAGTGCTTATGA +AAATTTTAATCAGCACGAAGTTCTACTTGCACCATTATTATCAGCTGGTATTTTTGGTGCTGACCCTATACA +TTCTTTAAGAGTTTGTGTAGATACTGTTCGCACAAATGTCTACTTAGCTGTCTTTGATAAAAATCTCTATGA +CAAACTTGTTTCAAGCTTTTTGGAAATGAAGAGTGAAAAGCAAGTTGAACAAAAGATCGCTGAGATTCCTAA +AGAGGAAGTTAAGCCATTTATAACTGAAAGTAAACCTTCAGTTGAACAGAGAAAACAAGATGATAAGAAAAT +CAAAGCTTGTGTTGAAGAAGTTACAACAACTCTGGAAGAAACTAAGTTCCTCACAGAAAACTTGTTACTTTA +TATTGACATTAATGGCAATCTTCATCCAGATTCTGCCACTCTTGTTAGTGACATTGACATCACTTTCTTAAA +GAAAGATGCTCCATATATAGTGGGTGATGTTGTTCAAGAGGGTGTTTTAACTGCTGTGGTTATACCTACTAA +AAAGGCTGGTGGCACTACTGAAATGCTAGCGAAAGCTTTGAGAAAAGTGCCAACAGACAATTATATAACCAC +TTACCCGGGTCAGGGTTTAAATGGTTACACTGTAGAGGAGGCAAAGACAGTGCTTAAAAAGTGTAAAAGTGC +CTTTTACATTCTACCATCTATTATCTCTAATGAGAAGCAAGAAATTCTTGGAACTGTTTCTTGGAATTTGCG +AGAAATGCTCGCACATGCAGAAGAAACACGCAAATTAATGCCTGTCTGTGTGGAAACTAAAGCCATAGTTTC +AACTATACAGCGTAAATATAAGGGTATTAAAATACAAGAGGGTGTGGTTGATTATGGTGCTAGATTTTACTT +TTACACCAGTAAAACAACTGTAGCGTCACTTATCAACACACTTAACGATCTAAATGAAACTCTTGTTACAAT +GCCACTTGGCTATGTAACACATGGCTTAAATTTGGAAGAAGCTGCTCGGTATATGAGATCTCTCAAAGTGCC +AGCTACAGTTTCTGTTTCTTCACCTGATGCTGTTACAGCGTATAATGGTTATCTTACTTCTTCTTCTAAAAC +ACCTGAAGAACATTTTATTGAAACCATCTCACTTGCTGGTTCCTATAAAGATTGGTCCTATTCTGGACAATC +TACACAACTAGGTATAGAATTTCTTAAGAGAGGTGATAAAAGTGTATATTACACTAGTAATCCTACCACATT +CCACCTAGATGGTGAAGTTATCACCTTTGACAATCTTAAGACACTTCTTTCTTTGAGAGAAGTGAGGACTAT +TAAGGTGTTTACAACAGTAGACAACATTAACCTCCACACGCAAGTTGTGGACATGTCAATGACATATGGACA +ACAGTTTGGTCCAACTTATTTTGATGGAGCTGATGTTACTAAAATAAAACCTCATAATTCACATGAAGGTAA +AACATTTTATGTTTTACCTAATGATGACACTCTACGTGTTGAGGCTTTTGAGTACTACCACACAACTGATCC +TAGTTTTCTGGGTAGGTACATGTCAGCATTAAATCACACTAAAAAGTGGAAATACCCACAAGTTAATGGTTT +AACTTCTATTAAATGGGCAGATAACAACTGTTATCTTGCCACTGCATTGTTAACACTCCAACAAATAGAGTT +GAAGTTTAATCCACCTGCTCTACAAGATGCTTATTACAGAGCAAGGGCTGGTGAAGCTGCTAACTTTTGTGC +ACTTATCTTAGCCTACTGTAATAAGACAGTAGGTGAGTTAGGTGATGTTAGAGAAACAATGAGTTACTTGTT +TCAACATGCCAATTTAGATTCTTGCAAAAGAGTCTTGAACGTGGTGTGTAAAACTTGTGGACAACAGCAGAC +AACCCTTAAGGGTGTAGAAGCTGTTATGTACATGGGCACACTTTCTTATGAACAATTTAAGAAAGGTGTTCA +GATACCTTGTACGTGTGGTAAACAAGCTACAAAATATCTAGTACAACAGGAGTCACCTTTTGTTATGATGTC +AGCACCACCTGCTCAGTATGAACTTAAGCATGGTACATTTACTTGTGCTAGTGAGTACACTGGTAATTACCA +GTGTGGTCACTATAAACATATAACTTCTAAAGAAACTTTGTATTGCATAGACGGTGCTTTACTTACAAAGTC +CTCAGAATACAAAGGTCCTATTACGGATGTTTTCTACAAAGAAAACAGTTACACAACAACCATAAAACCAGT +TACTTATAAATTGGATGGTGTTGTTTGTACAGAAATTGACCCTAAGTTGGACAATTATTATAAGAAAGACAA +TTCTTATTTCACAGAGCAACCAATTGATCTTGTACCAAACCAACCATATCCAAACGCAAGCTTCGATAATTT +TAAGTTTGTATGTGATAATATCAAATTTGCTGATGATTTAAACCAGTTAACTGGTTATAAGAAACCTGCTTC +AAGAGAGCTTAAAGTTACATTTTTCCCTGACTTAAATGGTGATGTGGTGGCTATTGATTATAAACACTACAC +ACCCTCTTTTAAGAAAGGAGCTAAATTGTTACATAAACCTATTGTTTGGCATGTTAACAATGCAACTAATAA +AGCCACGTATAAACCAAATACCTGGTGTATACGTTGTCTTTGGAGCACAAAACCAGTTGAAACATCAAATTC +GTTTGATGTACTGAAGTCAGAGGACGCGCAGGGAATGGATAATCTTGCCTGCGAAGATCTAAAACCAGTCTC +TGAAGAAGTAGTGGAAAATCCTACCATACAGAAAGACGTTCTTGAGTGTAATGTGAAAACTACCGAAGTTGT +AGGAGACATTATACTTAAACCAGCAAATAATAGTTTAAAAATTACAGAAGAGGTTGGCCACACAGATCTAAT +GGCTGCTTATGTAGACAATTCTAGTCTTACTATTAAGAAACCTAATGAATTATCTAGAGTATTAGGTTTGAA +AACCCTTGCTACTCATGGTTTAGCTGCTGTTAATAGTGTCCCTTGGGATACTATAGCTAATTATGCTAAGCC +TTTTCTTAACAAAGTTGTTAGTACAACTACTAACATAGTTACACGGTGTTTAAACCGTGTTTGTACTAATTA +TATGCCTTATTTCTTTACTTTATTGCTACAATTGTGTACTTTTACTAGAAGTACAAATTCTAGAATTAAAGC +ATCTATGCCGACTACTATAGCAAAGAATACTGTTAAGAGTGTCGGTAAATTTTGTCTAGAGGCTTCATTTAA +TTATTTGAAGTCACCTAATTTTTCTAAACTGATAAATATTATAATTTGGTTTTTACTATTAAGTGTTTGCCT +AGGTTCTTTAATCTACTCAACCGCTGCTTTAGGTGTTTTAATGTCTAATTTAGGCATGCCTTCTTACTGTAC +TGGTTACAGAGAAGGCTATTTGAACTCTACTAATGTCACTATTGCAACCTACTGTACTGGTTCTATACCTTG +TAGTGTTTGTCTTAGTGGTTTAGATTCTTTAGACACCTATCCTTCTTTAGAAACTATACAAATTACCATTTC +ATCTTTTAAATGGGATTTAACTGCTTTTGGCTTAGTTGCAGAGTGGTTTTTGGCATATATTCTTTTCACTAG +GTTTTTCTATGTACTTGGATTGGCTGCAATCATGCAATTGTTTTTCAGCTATTTTGCAGTACATTTTATTAG +TAATTCTTGGCTTATGTGGTTAATAATTAATCTTGTACAAATGGCCCCGATTTCAGCTATGGTTAGAATGTA +CATCTTCTTTGCATCATTTTATTATGTATGGAAAAGTTATGTGCATGTTGTAGACGGTTGTAATTCATCAAC +TTGTATGATGTGTTACAAACGTAATAGAGCAACAAGAGTCGAATGTACAACTATTGTTAATGGTGTTAGAAG +GTCCTTTTATGTCTATGCTAATGGAGGTAAAGGCTTTTGCAAACTACACAATTGGAATTGTGTTAATTGTGA +TACATTCTGTGCTGGTAGTACATTTATTAGTGATGAAGTTGCGAGAGACTTGTCACTACAGTTTAAAAGACC +AATAAATCCTACTGACCAGTCTTCTTACATCGTTGATAGTGTTACAGTGAAGAATGGTTCCATCCATCTTTA +CTTTGATAAAGCTGGTCAAAAGACTTATGAAAGACATTCTCTCTCTCATTTTGTTAACTTAGACAACCTGAG +AGCTAATAACACTAAAGGTTCATTGCCTATTAATGTTATAGTTTTTGATGGTAAATCAAAATGTGAAGAATC +ATCTGCAAAATCAGCGTCTGTTTACTACAGTCAGCTTATGTGTCAACCTATACTGTTACTAGATCAGGCATT +AGTGTCTGATGTTGGTGATAGTGCGGAAGTTGCAGTTAAAATGTTTGATGCTTACGTTAATACGTTTTCATC +AACTTTTAACGTACCAATGGAAAAACTCAAAACACTAGTTGCAACTGCAGAAGCTGAACTTGCAAAGAATGT +GTCCTTAGACAATGTCTTATCTACTTTTATTTCAGCAGCTCGGCAAGGGTTTGTTGATTCAGATGTAGAAAC +TAAAGATGTTGTTGAATGTCTTAAATTGTCACATCAATCTGACATAGAAGTTACTGGCGATAGTTGTAATAA +CTATATGCTCACCTATAACAAAGTTGAAAACATGACACCCCGTGACCTTGGTGCTTGTATTGACTGTAGTGC +GCGTCATATTAATGCGCAGGTAGCAAAAAGTCACAACATTGCTTTGATATGGAACGTTAAAGATTTCATGTC +ATTGTCTGAACAACTACGAAAACAAATACGTAGTGCTGCTAAAAAGAATAACTTACCTTTTAAGTTGACATG +TGCAACTACTAGACAAGTTGTTAATGTTGTAACAACAAAGATAGCACTTAAGGGTGGTAAAATTGTTAATAA +TTGGTTGAAGCAGTTAATTAAAGTTACACTTGTGTTCCTTTTTGTTGCTGCTATTTTCTATTTAATAACACC +TGTTCATGTCATGTCTAAACATACTGACTTTTCAAGTGAAATCATAGGATACAAGGCTATTGATGGTGGTGT +CACTCGTGACATAGCATCTACAGATACTTGTTTTGCTAACAAACATGCTGATTTTGACACATGGTTTAGTCA +GCGTGGTGGTAGTTATACTAATGACAAAGCTTGCCCATTGATTGCTGCAGTCATAACAAGAGAAGTGGGTTT +TGTCGTGCCTGGTTTGCCTGGCACGATATTACGCACAACTAATGGTGACTTTTTGCATTTCTTACCTAGAGT +TTTTAGTGCAGTTGGTAACATCTGTTACACACCATCAAAACTTATAGAGTACACTGACTTTGCAACATCAGC +TTGTGTTTTGGCTGCTGAATGTACAATTTTTAAAGATGCTTCTGGTAAGCCAGTACCATATTGTTATGATAC +CAATGTACTAGAAGGTTCTGTTGCTTATGAAAGTTTACGCCCTGACACACGTTATGTGCTCATGGATGGCTC +TATTATTCAATTTCCTAACACCTACCTTGAAGGTTCTGTTAGAGTGGTAACAACTTTTGATTCTGAGTACTG +TAGGCACGGCACTTGTGAAAGATCAGAAGCTGGTGTTTGTGTATCTACTAGTGGTAGATGGGTACTTAACAA +TGATTATTACAGATCTTTACCAGGAGTTTTCTGTGGTGTAGATGCTGTAAATTTACTTACTAATATGTTTAC +ACCACTAATTCAACCTATTGGTGCTTTGGACATATCAGCATCTATAGTAGCTGGTGGTATTGTAGCTATCGT +AGTAACATGCCTTGCCTACTATTTTATGAGGTTTAGAAGAGCTTTTGGTGAATACAGTCATGTAGTTGCCTT +TAATACTTTACTATTCCTTATGTCATTCACTGTACTCTGTTTAACACCAGTTTACTCATTCTTACCTGGTGT +TTATTCTGTTATTTACTTGTACTTGACATTTTATCTTACTAATGATGTTTCTTTTTTAGCACATATTCAGTG +GATGGTTATGTTCACACCTTTAGTACCTTTCTGGATAACAATTGCTTATATCATTTGTATTTCCACAAAGCA +TTTCTATTGGTTCTTTAGTAATTACCTAAAGAGACGTGTAGTCTTTAATGGTGTTTCCTTTAGTACTTTTGA +AGAAGCTGCGCTGTGCACCTTTTTGTTAAATAAAGAAATGTATCTAAAGTTGCGTAGTGATGTGCTATTACC +TCTTACGCAATATAATAGATACTTAGCTCTTTATAATAAGTACAAGTATTTTAGTGGAGCAATGGATACAAC +TAGCTACAGAGAAGCTGCTTGTTGTCATCTCGCAAAGGCTCTCAATGACTTCAGTAACTCAGGTTCTGATGT +TCTTTACCAACCACCACAAACCTCTATCACCTCAGCTGTTTTGCAGAGTGGTTTTAGAAAAATGGCATTCCC +ATCTGGTAAAGTTGAGGGTTGTATGGTACAAGTAACTTGTGGTACAACTACACTTAACGGTCTTTGGCTTGA +TGACGTAGTTTACTGTCCAAGACATGTGATCTGCACCTCTGAAGACATGCTTAACCCTAATTATGAAGATTT +ACTCATTCGTAAGTCTAATCATAATTTCTTGGTACAGGCTGGTAATGTTCAACTCAGGGTTATTGGACATTC +TATGCAAAATTGTGTACTTAAGCTTAAGGTTGATACAGCCAATCCTAAGACACCTAAGTATAAGTTTGTTCG +CATTCAACCAGGACAGACTTTTTCAGTGTTAGCTTGTTACAATGGTTCACCATCTGGTGTTTACCAATGTGC +TATGAGGCCCAATTTCACTATTAAGGGTTCATTCCTTAATGGTTCATGTGGTAGTGTTGGTTTTAACATAGA +TTATGACTGTGTCTCTTTTTGTTACATGCACCATATGGAATTACCAACTGGAGTTCATGCTGGCACAGACTT +AGAAGGTAACTTTTATGGACCTTTTGTTGACAGGCAAACAGCACAAGCAGCTGGTACGGACACAACTATTAC +AGTTAATGTTTTAGCTTGGTTGTACGCTGCTGTTATAAATGGAGACAGGTGGTTTCTCAATCGATTTACCAC +AACTCTTAATGACTTTAACCTTGTGGCTATGAAGTACAATTATGAACCTCTAACACAAGACCATGTTGACAT +ACTAGGACCTCTTTCTGCTCAAACTGGAATTGCCGTTTTAGATATGTGTGCTTCATTAAAAGAATTACTGCA +AAATGGTATGAATGGACGTACCATATTGGGTAGTGCTTTATTAGAAGATGAATTTACACCTTTTGATGTTGT +TAGACAATGCTCAGGTGTTACTTTCCAAAGTGCAGTGAAAAGAACAATCAAGGGTACACACCACTGGTTGTT +ACTCACAATTTTGACTTCACTTTTAGTTTTAGTCCAGAGTACTCAATGGTCTTTGTTCTTTTTTTTGTATGA +AAATGCCTTTTTACCTTTTGCTATGGGTATTATTGCTATGTCTGCTTTTGCAATGATGTTTGTCAAACATAA +GCATGCATTTCTCTGTTTGTTTTTGTTACCTTCTCTTGCCACTGTAGCTTATTTTAATATGGTCTATATGCC +TGCTAGTTGGGTGATGCGTATTATGACATGGTTGGATATGGTTGATACTAGTTTGTCTGGTTTTAAGCTAAA +AGACTGTGTTATGTATGCATCAGCTGTAGTGTTACTAATCCTTATGACAGCAAGAACTGTGTATGATGATGG +TGCTAGGAGAGTGTGGACACTTATGAATGTCTTGACACTCGTTTATAAAGTTTATTATGGTAATGCTTTAGA +TCAAGCCATTTCCATGTGGGCTCTTATAATCTCTGTTACTTCTAACTACTCAGGTGTAGTTACAACTGTCAT +GTTTTTGGCCAGAGGTATTGTTTTTATGTGTGTTGAGTATTGCCCTATTTTCTTCATAACTGGTAATACACT +TCAGTGTATAATGCTAGTTTATTGTTTCTTAGGCTATTTTTGTACTTGTTACTTTGGCCTCTTTTGTTTACT +CAACCGCTACTTTAGACTGACTCTTGGTGTTTATGATTACTTAGTTTCTACACAGGAGTTTAGATATATGAA +TTCACAGGGACTACTCCCACCCAAGAATAGCATAGATGCCTTCAAACTCAACATTAAATTGTTGGGTGTTGG +TGGCAAACCTTGTATCAAAGTAGCCACTGTACAGTCTAAAATGTCAGATGTAAAGTGCACATCAGTAGTCTT +ACTCTCAGTTTTGCAACAACTCAGAGTAGAATCATCATCTAAATTGTGGGCTCAATGTGTCCAGTTACACAA +TGACATTCTCTTAGCTAAAGATACTACTGAAGCCTTTGAAAAAATGGTTTCACTACTTTCTGTTTTGCTTTC +CATGCAGGGTGCTGTAGACATAAACAAGCTTTGTGAAGAAATGCTGGACAACAGGGCAACCTTACAAGCTAT +AGCCTCAGAGTTTAGTTCCCTTCCATCATATGCAGCTTTTGCTACTGCTCAAGAAGCTTATGAGCAGGCTGT +TGCTAATGGTGATTCTGAAGTTGTTCTTAAAAAGTTGAAGAAGTCTTTGAATGTGGCTAAATCTGAATTTGA +CCGTGATGCAGCCATGCAACGTAAGTTGGAAAAGATGGCTGATCAAGCTATGACCCAAATGTATAAACAGGC +TAGATCTGAGGACAAGAGGGCAAAAGTTACTAGTGCTATGCAGACAATGCTTTTCACTATGCTTAGAAAGTT +GGATAATGATGCACTCAACAACATTATCAACAATGCAAGAGATGGTTGTGTTCCCTTGAACATAATACCTCT +TACAACAGCAGCCAAACTAATGGTTGTCATACCAGACTATAACACATATAAAAATACGTGTGATGGTACAAC +ATTTACTTATGCATCAGCATTGTGGGAAATCCAACAGGTTGTAGATGCAGATAGTAAAATTGTTCAACTTAG +TGAAATTAGTATGGACAATTCACCTAATTTAGCATGGCCTCTTATTGTAACAGCTTTAAGGGCCAATTCTGC +TGTCAAATTACAGAATAATGAGCTTAGTCCTGTTGCACTACGACAGATGTCTTGTGCTGCCGGTACTACACA +AACTGCTTGCACTGATGACAATGCGTTAGCTTACTACAACACAACAAAGGGAGGTAGGTTTGTACTTGCACT +GTTATCCGATTTACAGGATTTGAAATGGGCTAGATTCCCTAAGAGTGATGGAACTGGTACTATCTATACAGA +ACTGGAACCACCTTGTAGGTTTGTTACAGACACACCTAAAGGTCCTAAAGTGAAGTATTTATACTTTATTAA +AGGATTAAACAACCTAAATAGAGGTATGGTACTTGGTAGTTTAGCTGCCACAGTACGTCTACAAGCTGGTAA +TGCAACAGAAGTGCCTGCCAATTCAACTGTATTATCTTTCTGTGCTTTTGCTGTAGATGCTGCTAAAGCTTA +CAAAGATTATCTAGCTAGTGGGGGACAACCAATCACTAATTGTGTTAAGATGTTGTGTACACACACTGGTAC +TGGTCAGGCAATAACAGTTACACCGGAAGCCAATATGGATCAAGAATCCTTTGGTGGTGCATCGTGTTGTCT +GTACTGCCGTTGCCACATAGATCATCCAAATCCTAAAGGATTTTGTGACTTAAAAGGTAAGTATGTACAAAT +ACCTACAACTTGTGCTAATGACCCTGTGGGTTTTACACTTAAAAACACAGTCTGTACCGTCTGCGGTATGTG +GAAAGGTTATGGCTGTAGTTGTGATCAACTCCGCGAACCCATGCTTCAGTCAGCTGATGCACAATCGTTTTT +AAACGGGTTTGCGGTGTAAGTGCAGCCCGTCTTACACCGTGCGGCACAGGCACTAGTACTGATGTCGTATAC +AGGGCTTTTGACATCTACAATGATAAAGTAGCTGGTTTTGCTAAATTCCTAAAAACTAATTGTTGTCGCTTC +CAAGAAAAGGACGAAGATGACAATTTAATTGATTCTTACTTTGTAGTTAAGAGACACACTTTCTCTAACTAC +CAACATGAAGAAACAATTTATAATTTACTTAAGGATTGTCCAGCTGTTGCTAAACATGACTTCTTTAAGTTT +AGAATAGACGGTGACATGGTACCACATATATCACGTCAACGTCTTACTAAATACACAATGGCAGACCTCGTC +TATGCTTTAAGGCATTTTGATGAAGGTAATTGTGACACATTAAAAGAAATACTTGTCACATACAATTGTTGT +GATGATGATTATTTCAATAAAAAGGACTGGTATGATTTTGTAGAAAACCCAGATATATTACGCGTATACGCC +AACTTAGGTGAACGTGTACGCCAAGCTTTGTTAAAAACAGTACAATTCTGTGATGCCATGCGAAATGCTGGT +ATTGTTGGTGTACTGACATTAGATAATCAAGATCTCAATGGTAACTGGTATGATTTCGGTGATTTCATACAA +ACCACGCCAGGTAGTGGAGTTCCTGTTGTAGATTCTTATTATTCATTGTTAATGCCTATATTAACCTTGACC +AGGGCTTTAACTGCAGAGTCACATGTTGACACTGACTTAACAAAGCCTTACATTAAGTGGGATTTGTTAAAA +TATGACTTCACGGAAGAGAGGTTAAAACTCTTTGACCGTTATTTTAAATATTGGGATCAGACATACCACCCA +AATTGTGTTAACTGTTTGGATGACAGATGCATTCTGCATTGTGCAAACTTTAATGTTTTATTCTCTACAGTG +TTCCCACCTACAAGTTTTGGACCACTAGTGAGAAAAATATTTGTTGATGGTGTTCCATTTGTAGTTTCAACT +GGATACCACTTCAGAGAGCTAGGTGTTGTACATAATCAGGATGTAAACTTACATAGCTCTAGACTTAGTTTT +AAGGAATTACTTGTGTATGCTGCTGACCCTGCTATGCACGCTGCTTCTGGTAATCTATTACTAGATAAACGC +ACTACGTGCTTTTCAGTAGCTGCACTTACTAACAATGTTGCTTTTCAAACTGTCAAACCCGGTAATTTTAAC +AAAGACTTCTATGACTTTGCTGTGTCTAAGGGTTTCTTTAAGGAAGGAAGTTCTGTTGAATTAAAACACTTC +TTCTTTGCTCAGGATGGTAATGCTGCTATCAGCGATTATGACTACTATCGTTATAATCTACCAACAATGTGT +GATATCAGACAACTACTATTTGTAGTTGAAGTTGTTGATAAGTACTTTGATTGTTACGATGGTGGCTGTATT +AATGCTAACCAAGTCATCGTCAACAACCTAGACAAATCAGCTGGTTTTCCATTTAATAAATGGGGTAAGGCT +AGACTTTATTATGATTCAATGAGTTATGAGGATCAAGATGCACTTTTCGCATATACAAAACGTAATGTCATC +CCTACTATAACTCAAATGAATCTTAAGTATGCCATTAGTGCAAAGAATAGAGCTCGCACCGTAGCTGGTGTC +TCTATCTGTAGTACTATGACCAATAGACAGTTTCATCAAAAATTATTGAAATCAATAGCCGCCACTAGAGGA +GCTACTGTAGTAATTGGAACAAGCAAATTCTATGGTGGTTGGCACAACATGTTAAAAACTGTTTATAGTGAT +GTAGAAAACCCTCACCTTATGGGTTGGGATTATCCTAAATGTGATAGAGCCATGCCTAACATGCTTAGAATT +ATGGCCTCACTTGTTCTTGCTCGCAAACATACAACGTGTTGTAGCTTGTCACACCGTTTCTATAGATTAGCT +AATGAGTGTGCTCAAGTATTGAGTGAAATGGTCATGTGTGGCGGTTCACTATATGTTAAACCAGGTGGAACC +TCATCAGGAGATGCCACAACTGCTTATGCTAATAGTGTTTTTAACATTTGTCAAGCTGTCACGGCCAATGTT +AATGCACTTTTATCTACTGATGGTAACAAAATTGCCGATAAGTATGTCCGCAATTTACAACACAGACTTTAT +GAGTGTCTCTATAGAAATAGAGATGTTGACACAGACTTTGTGAATGAGTTTTACGCATATTTGCGTAAACAT +TTCTCAATGATGATACTCTCTGACGATGCTGTTGTGTGTTTCAATAGCACTTATGCATCTCAAGGTCTAGTG +GCTAGCATAAAGAACTTTAAGTCAGTTCTTTATTATCAAAACAATGTTTTTATGTCTGAAGCAAAATGTTGG +ACTGAGACTGACCTTACTAAAGGACCTCATGAATTTTGCTCTCAACATACAATGCTAGTTAAACAGGGTGAT +GATTATGTGTACCTTCCTTACCCAGATCCATCAAGAATCCTAGGGGCCGGCTGTTTTGTAGATGATATCGTA +AAAACAGATGGTACACTTATGATTGAACGGTTCGTGTCTTTAGCTATAGATGCTTACCCACTTACTAAACAT +CCTAATCAGGAGTATGCTGATGTCTTTCATTTGTACTTACAATACATAAGAAAGCTACATGATGAGTTAACA +GGACACATGTTAGACATGTATTCTGTTATGCTTACTAATGATAACACTTCAAGGTATTGGGAACCTGAGTTT +TATGAGGCTATGTACACACCGCATACAGTCTTACAGGCTGTTGGGGCTTGTGTTCTTTGCAATTCACAGACT +TCATTAAGATGTGGTGCTTGCATACGTAGACCATTCTTATGTTGTAAATGCTGTTACGACCATGTCATATCA +ACATCACATAAATTAGTCTTGTCTGTTAATCCGTATGTTTGCAATGCTCCAGGTTGTGATGTCACAGATGTG +ACTCAACTTTACTTAGGAGGTATGAGCTATTATTGTAAATCACATAAACCACCCATTAGTTTTCCATTGTGT +GCTAATGGACAAGTTTTTGGTTTATATAAAAATACATGTGTTGGTAGCGATAATGTTACTGACTTTAATGCA +ATTGCAACATGTGACTGGACAAATGCTGGTGATTACATTTTAGCTAACACCTGTACTGAAAGACTCAAGCTT +TTTGCAGCAGAAACGCTCAAAGCTACTGAGGAGACATTTAAACTGTCTTATGGTATTGCTACTGTACGTGAA +GTGCTGTCTGACAGAGAATTACATCTTTCATGGGAAGTTGGTAAACCTAGACCACCACTTAACCGAAATTAT +GTCTTTACTGGTTATCGTGTAACTAAAAACAGTAAAGTACAAATAGGAGAGTACACCTTTGAAAAAGGTGAC +TATGGTGATGCTGTTGTTTACCGAGGTACAACAACTTACAAATTAAATGTTGGTGATTATTTTGTGCTGACA +TCACATACAGTAATGCCATTAAGTGCACCTACACTAGTGCCACAAGAGCACTATGTTAGAATTACTGGCTTA +TACCCAACACTCAATATCTCAGATGAGTTTTCTAGCAATGTTGCAAATTATCAAAAGGTTGGTATGCAAAAG +TATTCTACACTCCAGGGACCACCTGGTACTGGTAAGAGTCATTTTGCTATTGGCCTAGCTCTCTACTACCCT +TCTGCTCGCATAGTGTATACAGCTTGCTCTCATGCCGCTGTTGATGCACTATGTGAGAAGGCATTAAAATAT +TTGCCTATAGATAAATGTAGTAGAATTATACCTGCACGTGCTCGTGTAGAGTGTTTTGATAAATTCAAAGTG +AATTCAACATTAGAACAGTATGTCTTTTGTACTGTAAATGCATTGCCTGAGACGACAGCAGATATAGTTGTC +TTTGATGAAATTTCAATGGCCACAAATTATGATTTGAGTGTTGTCAATGCCAGATTACGTGCTAAGCACTAT +GTGTACATTGGCGACCCTGCTCAATTACCTGCACCACGCACATTGCTAACTAAGGGCACACTAGAACCAGAA +TATTTCAATTCAGTGTGTAGACTTATGAAAACTATAGGTCCAGACATGTTCCTCGGAACTTGTCGGCGTTGT +CCTGCTGAAATTGTTGACACTGTGAGTGCTTTGGTTTATGATAATAAGCTTAAAGCACATAAAGACAAATCA +GCTCAATGCTTTAAAATGTTTTATAAGGGTGTTATCACGCATGATGTTTCATCTGCAATTAACAGGCCACAA +ATAGGCGTGGTAAGAGAATTCCTTACACGTAACCCTGCTTGGAGAAAAGCTGTCTTTATTTCACCTTATAAT +TCACAGAATGCTGTAGCCTCAAAGATTTTGGGACTACCAACTCAAACTGTTGATTCATCACAGGGCTCAGAA +TATGACTATGTCATATTCACTCAAACCACTGAAACAGCTCACTCTTGTAATGTAAACAGATTTAATGTTGCT +ATTACCAGAGCAAAAGTAGGCATACTTTGCATAATGTCTGATAGAGACCTTTATGACAAGTTGCAATTTACA +AGTCTTGAAATTCCACGTAGGAATGTGGCAACTTTACAAGCTGAAAATGTAACAGGACTCTTTAAAGATTGT +AGTAAGGTAATCACTGGGTTACATCCTACACAGGCACCTACACACCTCAGTGTTGACACTAAATTCAAAACT +GAAGGTTTATGTGTTGACATACCTGGCATACCTAAGGACATGACCTATAGAAGACTCATCTCTATGATGGGT +TTTAAAATGAATTATCAAGTTAATGGTTACCCTAACATGTTTATCACCCGCGAAGAAGCTATAAGACATGTA +CGTGCATGGATTGGCTTCGATGTCGAGGGGTGTCATGCTACTAGAGAAGCTGTTGGTACCAATTTACCTTTA +CAGCTAGGTTTTTCTACAGGTGTTAACCTAGTTGCTGTACCTACAGGTTATGTTGATACACCTAATAATACA +GATTTTTCCAGAGTTAGTGCTAAACCACCGCCTGGAGATCAATTTAAACACCTCATACCACTTATGTACAAA +GGACTTCCTTGGAATGTAGTGCGTATAAAGATTGTACAAATGTTAAGTGACACACTTAAAAATCTCTCTGAC +AGAGTCGTATTTGTCTTATGGGCACATGGCTTTGAGTTGACATCTATGAAGTATTTTGTGAAAATAGGACCT +GAGCGCACCTGTTGTCTATGTGATAGACGTGCCACATGCTTTTCCACTGCTTCAGACACTTATGCCTGTTGG +CATCATTCTATTGGATTTGATTACGTCTATAATCCGTTTATGATTGATGTTCAACAATGGGGTTTTACAGGT +AACCTACAAAGCAACCATGATCTGTATTGTCAAGTCCATGGTAATGCACATGTAGCTAGTTGTGATGCAATC +ATGACTAGGTGTCTAGCTGTCCACGAGTGCTTTGTTAAGCGTGTTGACTGGACTATTGAATATCCTATAATT +GGTGATGAACTGAAGATTAATGCGGCTTGTAGAAAGGTTCAACACATGGTTGTTAAAGCTGCATTATTAGCA +GACAAATTCCCAGTTCTTCACGACATTGGTAACCCTAAAGCTATTAAGTGTGTACCTCAAGCTGATGTAGAA +TGGAAGTTCTATGATGCACAGCCTTGTAGTGACAAAGCTTATAAAATAGAAGAATTATTCTATTCTTATGCC +ACACATTCTGACAAATTCACAGATGGTGTATGCCTATTTTGGAATTGCAATGTCGATAGATATCCTGCTAAT +TCCATTGTTTGTAGATTTGACACTAGAGTGCTATCTAACCTTAACTTGCCTGGTTGTGATGGTGGCAGTTTG +TATGTAAATAAACATGCATTCCACACACCAGCTTTTGATAAAAGTGCTTTTGTTAATTTAAAACAATTACCA +TTTTTCTATTACTCTGACAGTCCATGTGAGTCTCATGGAAAACAAGTAGTGTCAGATATAGATTATGTACCA +CTAAAGTCTGCTACGTGTATAACACGTTGCAATTTAGGTGGTGCTGTCTGTAGACATCATGCTAATGAGTAC +AGATTGTATCTCGATGCTTATAACATGATGATCTCAGCTGGCTTTAGCTTGTGGGTTTACAAACAATTTGAT +ACTTATAACCTCTGGAACACTTTTACAAGACTTCAGAGTTTAGAAAATGTGGCTTTTAATGTTGTAAATAAG +GGACACTTTGATGGACAACAGGGTGAAGTACCAGTTTCTATCATTAATAACACTGTTTACACAAAAGTTGAT +GGTGTTGATGTAGAATTGTTTGAAAATAAAACAACATTACCTGTTAATGTAGCATTTGAGCTTTGGGCTAAG +CGCAACATTAAACCAGTACCAGAGGTGAAAATACTCAATAATTTGGGTGTGGACATTGCTGCTAATACTGTG +ATCTGGGACTACAAAAGAGATGCTCCAGCACATATATCTACTATTGGTGTTTGTTCTATGACTGACATAGCC +AAGAAACCAACTGAAACGATTTGTGCACCACTCACTGTCTTTTTTGATGGTAGAGTTGATGGTCAAGTAGAC +TTATTTAGAAATGCCCGTAATGGTGTTCTTATTACAGAAGGTAGTGTTAAAGGTTTACAACCATCTGTAGGT +CCCAAACAAGCTAGTCTTAATGGAGTCACATTAATTGGAGAAGCCGTAAAAACACAGTTCAATTATTATAAG +AAAGTTGATGGTGTTGTCCAACAATTACCTGAAACTTACTTTACTCAGAGTAGAAATTTACAAGAATTTAAA +CCCAGGAGTCAAATGGAAATTGATTTCTTAGAATTAGCTATGGATGAATTCATTGAACGGTATAAATTAGAA +GGCTATGCCTTCGAACATATCGTTTATGGAGATTTTAGTCATAGTCAGTTAGGTGGTTTACATCTACTGATT +GGACTAGCTAAACGTTTTAAGGAATCACCTTTTGAATTAGAAGATTTTATTCCTATGGACAGTACAGTTAAA +AACTATTTCATAACAGATGCGCAAACAGGTTCATCTAAGTGTGTGTGTTCTGTTATTGATTTATTACTTGAT +GATTTTGTTGAAATAATAAAATCCCAAGATTTATCTGTAGTTTCTAAGGTTGTCAAAGTGACTATTGACTAT +ACAGAAATTTCATTTATGCTTTGGTGTAAAGATGGCCATGTAGAAACATTTTACCCAAAATTACAATCTAGT +CAAGCGTGGCAACCGGGTGTTGCTATGCCTAATCTTTACAAAATGCAAAGAATGCTATTAGAAAAGTGTGAC +CTTCAAAATTATGGTGATAGTGCAACATTACCTAAAGGCATAATGATGAATGTCGCAAAATATACTCAACTG +TGTCAATATTTAAACACATTAACATTAGCTGTACCCTATAATATGAGAGTTATACATTTTGGTGCTGGTTCT +GATAAAGGAGTTGCACCAGGTACAGCTGTTTTAAGACAGTGGTTGCCTACGGGTACGCTGCTTGTCGATTCA +GATCTTAATGACTTTGTCTCTGATGCAGATTCAACTTTGATTGGTGATTGTGCAACTGTACATACAGCTAAT +AAATGGGATCTCATTATTAGTGATATGTACGACCCTAAGACTAAAAATGTTACAAAAGAAAATGACTCTAAA +GAGGGTTTTTTCACTTACATTTGTGGGTTTATACAACAAAAGCTAGCTCTTGGAGGTTCCGTGGCTATAAAG +ATAACAGAACATTCTTGGAATGCTGATCTTTATAAGCTCATGGGACACTTCGCATGGTGGACAGCCTTTGTT +ACTAATGTGAATGCGTCATCATCTGAAGCATTTTTAATTGGATGTAATTATCTTGGCAAACCACGCGAACAA +ATAGATGGTTATGTCATGCATGCAAATTACATATTTTGGAGGAATACAAATCCAATTCAGTTGTCTTCCTAT +TCTTTATTTGACATGAGTAAATTTCCCCTTAAATTAAGGGGTACTGCTGTTATGTCTTTAAAAGAAGGTCAA +ATCAATGATATGATTTTATCTCTTCTTAGTAAAGGTAGACTTATAATTAGAGAAAACAACAGAGTTGTTATT +TCTAGTGATGTTCTTGTTAACAACTAAACGAACAATGTTTGTTTTTCTTGTTTTATTGCCACTAGTCTCTAG +TCAGTGTGTTAATCTTACAACCAGAACTCAATTACCCCCTGCATACACTAATTCTTTCACACGTGGTGTTTA +TTACCCTGACAAAGTTTTCAGATCCTCAGTTTTACATTCAACTCAGGACTTGTTCTTACCTTTCTTTTCCAA +TGTTACTTGGTTCCATGCTATACATGTCTCTGGGACCAATGGTACTAAGAGGTTTGATAACCCTGTCCTACC +ATTTAATGATGGTGTTTATTTTGCTTCCACTGAGAAGTCTAACATAATAAGAGGCTGGATTTTTGGTACTAC +TTTAGATTCGAAGACCCAGTCCCTACTTATTGTTAATAACGCTACTAATGTTGTTATTAAAGTCTGTGAATT +TCAATTTTGTAATGATCCATTTTTGGGTGTTTATTACCACAAAAACAACAAAAGTTGGATGGAAAGTGAGTT +CAGAGTTTATTCTAGTGCGAATAATTGCACTTTTGAATATGTCTCTCAGCCTTTTCTTATGGACCTTGAAGG +AAAACAGGGTAATTTCAAAAATCTTAGGGAATTTGTGTTTAAGAATATTGATGGTTATTTTAAAATATATTC +TAAGCACACGCCTATTAATTTAGTGCGTGATCTCCCTCAGGGTTTTTCGGCTTTAGAACCATTGGTAGATTT +GCCAATAGGTATTAACATCACTAGGTTTCAAACTTTACTTGCTTTACATAGAAGTTATTTGACTCCTGGTGA +TTCTTCTTCAGGTTGGACAGCTGGTGCTGCAGCTTATTATGTGGGTTATCTTCAACCTAGGACTTTTCTATT +AAAATATAATGAAAATGGAACCATTACAGATGCTGTAGACTGTGCACTTGACCCTCTCTCAGAAACAAAGTG +TACGTTGAAATCCTTCACTGTAGAAAAAGGAATCTATCAAACTTCTAACTTTAGAGTCCAACCAACAGAATC +TATTGTTAGATTTCCTAATATTACAAACTTGTGCCCTTTTGGTGAAGTTTTTAACGCCACCAGATTTGCATC +TGTTTATGCTTGGAACAGGAAGAGAATCAGCAACTGTGTTGCTGATTATTCTGTCCTATATAATTCCGCATC +ATTTTCCACTTTTAAGTGTTATGGAGTGTCTCCTACTAAATTAAATGATCTCTGCTTTACTAATGTCTATGC +AGATTCATTTGTAATTAGAGGTGATGAAGTCAGACAAATCGCTCCAGGGCAAACTGGAAAGATTGCTGATTA +TAATTATAAATTACCAGATGATTTTACAGGCTGCGTTATAGCTTGGAATTCTAACAATCTTGATTCTAAGGT +TGGTGGTAATTATAATTACCTGTATAGATTGTTTAGGAAGTCTAATCTCAAACCTTTTGAGAGAGATATTTC +AACTGAAATCTATCAGGCCGGTAGCACACCTTGTAATGGTGTTGAAGGTTTTAATTGTTACTTTCCTTTACA +ATCATATGGTTTCCAACCCACTAATGGTGTTGGTTACCAACCATACAGAGTAGTAGTACTTTCTTTTGAACT +TCTACATGCACCAGCAACTGTTTGTGGACCTAAAAAGTCTACTAATTTGGTTAAAAACAAATGTGTCAATTT +CAACTTCAATGGTTTAACAGGCACAGGTGTTCTTACTGAGTCTAACAAAAAGTTTCTGCCTTTCCAACAATT +TGGCAGAGACATTGCTGACACTACTGATGCTGTCCGTGATCCACAGACACTTGAGATTCTTGACATTACACC +ATGTTCTTTTGGTGGTGTCAGTGTTATAACACCAGGAACAAATACTTCTAACCAGGTTGCTGTTCTTTATCA +GGATGTTAACTGCACAGAAGTCCCTGTTGCTATTCATGCAGATCAACTTACTCCTACTTGGCGTGTTTATTC +TACAGGTTCTAATGTTTTTCAAACACGTGCAGGCTGTTTAATAGGGGCTGAACATGTCAACAACTCATATGA +GTGTGACATACCCATTGGTGCAGGTATATGCGCTAGTTATCAGACTCAGACTAATTCTCCTCGGCGGGCACG +TAGTGTAGCTAGTCAATCCATCATTGCCTACACTATGTCACTTGGTGCAGAAAATTCAGTTGCTTACTCTAA +TAACTCTATTGCCATACCCACAAATTTTACTATTAGTGTTACCACAGAAATTCTACCAGTGTCTATGACCAA +GACATCAGTAGATTGTACAATGTACATTTGTGGTGATTCAACTGAATGCAGCAATCTTTTGTTGCAATATGG +CAGTTTTTGTACACAATTAAACCGTGCTTTAACTGGAATAGCTGTTGAACAAGACAAAAACACCCAAGAAGT +TTTTGCACAAGTCAAACAAATTTACAAAACACCACCAATTAAAGATTTTGGTGGTTTTAATTTTTCACAAAT +ATTACCAGATCCATCAAAACCAAGCAAGAGGTCATTTATTGAAGATCTACTTTTCAACAAAGTGACACTTGC +AGATGCTGGCTTCATCAAACAATATGGTGATTGCCTTGGTGATATTGCTGCTAGAGACCTCATTTGTGCACA +AAAGTTTAACGGCCTTACTGTTTTGCCACCTTTGCTCACAGATGAAATGATTGCTCAATACACTTCTGCACT +GTTAGCGGGTACAATCACTTCTGGTTGGACCTTTGGTGCAGGTGCTGCATTACAAATACCATTTGCTATGCA +AATGGCTTATAGGTTTAATGGTATTGGAGTTACACAGAATGTTCTCTATGAGAACCAAAAATTGATTGCCAA +CCAATTTAATAGTGCTATTGGCAAAATTCAAGACTCACTTTCTTCCACAGCAAGTGCACTTGGAAAACTTCA +AGATGTGGTCAACCAAAATGCACAAGCTTTAAACACGCTTGTTAAACAACTTAGCTCCAATTTTGGTGCAAT +TTCAAGTGTTTTAAATGATATCCTTTCACGTCTTGACAAAGTTGAGGCTGAAGTGCAAATTGATAGGTTGAT +CACAGGCAGACTTCAAAGTTTGCAGACATATGTGACTCAACAATTAATTAGAGCTGCAGAAATCAGAGCTTC +TGCTAATCTTGCTGCTACTAAAATGTCAGAGTGTGTACTTGGACAATCAAAAAGAGTTGATTTTTGTGGAAA +GGGCTATCATCTTATGTCCTTCCCTCAGTCAGCACCTCATGGTGTAGTCTTCTTGCATGTGACTTATGTCCC +TGCACAAGAAAAGAACTTCACAACTGCTCCTGCCATTTGTCATGATGGAAAAGCACACTTTCCTCGTGAAGG +TGTCTTTGTTTCAAATGGCACACACTGGTTTGTAACACAAAGGAATTTTTATGAACCACAAATCATTACTAC +AGACAACACATTTGTGTCTGGTAACTGTGATGTTGTAATAGGAATTGTCAACAACACAGTTTATGATCCTTT +GCAACCTGAATTAGACTCATTCAAGGAGGAGTTAGATAAATATTTTAAGAATCATACATCACCAGATGTTGA +TTTAGGTGACATCTCTGGCATTAATGCTTCAGTTGTAAACATTCAAAAAGAAATTGACCGCCTCAATGAGGT +TGCCAAGAATTTAAATGAATCTCTCATCGATCTCCAAGAACTTGGAAAGTATGAGCAGTATATAAAATGGCC +ATGGTACATTTGGCTAGGTTTTATAGCTGGCTTGATTGCCATAGTAATGGTGACAATTATGCTTTGCTGTAT +GACCAGTTGCTGTAGTTGTCTCAAGGGCTGTTGTTCTTGTGGATCCTGCTGCAAATTTGATGAAGACGACTC +TGAGCCAGTGCTCAAAGGAGTCAAATTACATTACACATAAACGAACTTATGGATTTGTTTATGAGAATCTTC +ACAATTGGAACTGTAACTTTGAAGCAAGGTGAAATCAAGGATGCTACTCCTTCAGATTTTGTTCGCGCTACT +GCAACGATACCGATACAAGCCTCACTCCCTTTCGGATGGCTTATTGTTGGCGTTGCACTTCTTGCTGTTTTT +CAGAGCGCTTCCAAAATCATAACCCTCAAAAAGAGATGGCAACTAGCACTCTCCAAGGGTGTTCACTTTGTT +TGCAACTTGCTGTTGTTGTTTGTAACAGTTTACTCACACCTTTTGCTCGTTGCTGCTGGCCTTGAAGCCCCT +TTTCTCTATCTTTATGCTTTAGTCTACTTCTTGCAGAGTATAAACTTTGTAAGAATAATAATGAGGCTTTGG +CTTTGCTGGAAATGCCGTTCCAAAAACCCATTACTTTATGATGCCAACTATTTTCTTTGCTGGCATACTAAT +TGTTACGACTATTGTATACCTTACAATAGTGTAACTTCTTCAATTGTCATTACTTCAGGTGATGGCACAACA +AGTCCTATTTCTGAACATGACTACCAGATTGGTGGTTATACTGAAAAATGGGAATCTGGAGTAAAAGACTGT +GTTGTATTACACAGTTACTTCACTTCAGACTATTACCAGCTGTACTCAACTCAATTGAGTACAGACACTGGT +GTTGAACATGTTACCTTCTTCATCTACAATAAAATTGTTGATGAGCCTGAAGAACATGTCCAAATTCACACA +ATCGACGGTTCATCCGGAGTTGTTAATCCAGTAATGGAACCAATTTATGATGAACCGACGACGACTACTAGC +GTGCCTTTGTAAGCACAAGCTGATGAGTACGAACTTATGTACTCATTCGTTTCGGAAGAGACAGGTACGTTA +ATAGTTAATAGCGTACTTCTTTTTCTTGCTTTCGTGGTATTCTTGCTAGTTACACTAGCCATCCTTACTGCG +CTTCGATTGTGTGCGTACTGCTGCAATATTGTTAACGTGAGTCTTGTAAAACCTTCTTTTTACGTTTACTCT +CGTGTTAAAAATCTGAATTCTTCTAGAGTTCCTGATCTTCTGGTCTAAACGAACTAAATATTATATTAGTTT +TTCTGTTTGGAACTTTAATTTTAGCCATGGCAGATTCCAACGGTACTATTACCGTTGAAGAGCTTAAAAAGC +TCCTTGAACAATGGAACCTAGTAATAGGTTTCCTATTCCTTACATGGATTTGTCTTCTACAATTTGCCTATG +CCAACAGGAATAGGTTTTTGTATATAATTAAGTTAATTTTCCTCTGGCTGTTATGGCCAGTAACTTTAGCTT +GTTTTGTGCTTGCTGCTGTTTACAGAATAAATTGGATCACCGGTGGAATTGCTATCGCAATGGCTTGTCTTG +TAGGCTTGATGTGGCTCAGCTACTTCATTGCTTCTTTCAGACTGTTTGCGCGTACGCGTTCCATGTGGTCAT +TCAATCCAGAAACTAACATTCTTCTCAACGTGCCACTCCATGGCACTATTCTGACCAGACCGCTTCTAGAAA +GTGAACTCGTAATCGGAGCTGTGATCCTTCGTGGACATCTTCGTATTGCTGGACACCATCTAGGACGCTGTG +ACATCAAGGACCTGCCTAAAGAAATCACTGTTGCTACATCACGAACGCTTTCTTATTACAAATTGGGAGCTT +CGCAGCGTGTAGCAGGTGACTCAGGTTTTGCTGCATACAGTCGCTACAGGATTGGCAACTATAAATTAAACA +CAGACCATTCCAGTAGCAGTGACAATATTGCTTTGCTTGTACAGTAAGTGACAACAGATGTTTCATCTCGTT +GACTTTCAGGTTACTATAGCAGAGATATTACTAATTATTATGAGGACTTTTAAAGTTTCCATTTGGAATCTT +GATTACATCATAAACCTCATAATTAAAAATTTATCTAAGTCACTAACTGAGAATAAATATTCTCAATTAGAT +GAAGAGCAACCAATGGAGATTGATTAAACGAACATGAAAATTATTCTTTTCTTGGCACTGATAACACTCGCT +ACTTGTGAGCTTTATCACTACCAAGAGTGTGTTAGAGGTACAACAGTACTTTTAAAAGAACCTTGCTCTTCT +GGAACATACGAGGGCAATTCACCATTTCATCCTCTAGCTGATAACAAATTTGCACTGACTTGCTTTAGCACT +CAATTTGCTTTTGCTTGTCCTGACGGCGTAAAACACGTCTATCAGTTACGTGCCAGATCAGTTTCACCTAAA +CTGTTCATCAGACAAGAGGAAGTTCAAGAACTTTACTCTCCAATTTTTCTTATTGTTGCGGCAATAGTGTTT +ATAACACTTTGCTTCACACTCAAAAGAAAGACAGAATGATTGAACTTTCATTAATTGACTTCTATTTGTGCT +TTTTAGCCTTTCTGCTATTCCTTGTTTTAATTATGCTTATTATCTTTTGGTTCTCACTTGAACTGCAAGATC +ATAATGAAACTTGTCACGCCTAAACGAACATGAAATTTCTTGTTTTCTTAGGAATCATCACAACTGTAGCTG +CATTTCACCAAGAATGTAGTTTACAGTCATGTACTCAACATCAACCATATGTAGTTGATGACCCGTGTCCTA +TTCACTTCTATTCTAAATGGTATATTAGAGTAGGAGCTAGAAAATCAGCACCTTTAATTGAATTGTGCGTGG +ATGAGGCTGGTTCTAAATCACCCATTCAGTACATCGATATCGGTAATTATACAGTTTCCTGTTCACCTTTTA +CAATTAATTGCCAGGAACCTAAATTGGGTAGTCTTGTAGTGCGTTGTTCGTTCTATGAAGACTTTTTAGAGT +ATCATGACGTTCGTGTTGTTTTAGATTTCATCTAAACGAACAAACTAAAATGTCTGATAATGGACCCCAAAA +TCAGCGAAATGCACCCCGCATTACGTTTGGTGGACCCTCAGATTCAACTGGCAGTAACCAGAATGGAGAACG +CAGTGGGGCGCGATCAAAACAACGTCGGCCCCAAGGTTTACCCAATAATACTGCGTCTTGGTTCACCGCTCT +CACTCAACATGGCAAGGAAGACCTTAAATTCCCTCGAGGACAAGGCGTTCCAATTAACACCAATAGCAGTCC +AGATGACCAAATTGGCTACTACCGAAGAGCTACCAGACGAATTCGTGGTGGTGACGGTAAAATGAAAGATCT +CAGTCCAAGATGGTATTTCTACTACCTAGGAACTGGGCCAGAAGCTGGACTTCCCTATGGTGCTAACAAAGA +CGGCATCATATGGGTTGCAACTGAGGGAGCCTTGAATACACCAAAAGATCACATTGGCACCCGCAATCCTGC +TAACAATGCTGCAATCGTGCTACAACTTCCTCAAGGAACAACATTGCCAAAAGGCTTCTACGCAGAAGGGAG +CAGAGGCGGCAGTCAAGCCTCTTCTCGTTCCTCATCACGTAGTCGCAACAGTTCAAGAAATTCAACTCCAGG +CAGCAGTAGGGGAACTTCTCCTGCTAGAATGGCTGGCAATGGCGGTGATGCTGCTCTTGCTTTGCTGCTGCT +TGACAGATTGAACCAGCTTGAGAGCAAAATGTCTGGTAAAGGCCAACAACAACAAGGCCAAACTGTCACTAA +GAAATCTGCTGCTGAGGCTTCTAAGAAGCCTCGGCAAAAACGTACTGCCACTAAAGCATACAATGTAACACA +AGCTTTCGGCAGACGTGGTCCAGAACAAACCCAAGGAAATTTTGGGGACCAGGAACTAATCAGACAAGGAAC +TGATTACAAACATTGGCCGCAAATTGCACAATTTGCCCCCAGCGCTTCAGCGTTCTTCGGAATGTCGCGCAT +TGGCATGGAAGTCACACCTTCGGGAACGTGGTTGACCTACACAGGTGCCATCAAATTGGATGACAAAGATCC +AAATTTCAAAGATCAAGTCATTTTGCTGAATAAGCATATTGACGCATACAAAACATTCCCACCAACAGAGCC +TAAAAAGGACAAAAAGAAGAAGGCTGATGAAACTCAAGCCTTACCGCAGAGACAGAAGAAACAGCAAACTGT +GACTCTTCTTCCTGCTGCAGATTTGGATGATTTCTCCAAACAATTGCAACAATCCATGAGCAGTGCTGACTC +AACTCAGGCCTAAACTCATGCAGACCACACAAGGCAGATGGGCTATATAAACGTTTTCGCTTTTCCGTTTAC +GATATATAGTCTACTCTTGTGCAGAATGAATTCTCGTAACTACATAGCACAAGTAGATGTAGTTAACTTTAA +TCTCACATAGCAATCTTTAATCAGTGTGTAACATTAGGGAGGACTTGAAAGAGCCACCACATTTTCACCGAG +GCCACGCGGAGTACGATCGAGTGTACAGTGAACAATGCTAGGGAGAGCTGCCTATATGGAAGAGCCCTAATG +TGTAAAATTAATTTTAGTAGTGCTATCCCCATGTGATTTTAATAGCTTCTTAGGAGAATGACAAAAAAAAAA +AAAAAAAAAAAAAAAAAAAAAAA
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/sample1.tsv Tue May 05 06:57:10 2020 -0400 @@ -0,0 +1,236 @@ +#f30a0489-ec1e-4f6e-829e-fa6d16dbee2e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00664 0.0 0.0 124.18560791015625 122.90550231933594 20 +22102 GGAAA 2 0.00564 0.0 0.0 127.36959838867188 130.8000030517578 17 +#e924b30f-22dc-4156-8e5c-ba664abbe7a7 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0073 0.0 0.0 118.83446502685547 119.46699523925781 22 +22102 GGAAA 2 0.0249 0.0 0.0 124.0261459350586 123.86900329589844 75 +#d4988330-6f34-498a-b1e3-6574d8b3dae2 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.020249999999999997 0.0 0.0 118.07210540771484 119.5469970703125 61 +22102 GGAAA 1 0.00531 0.0 0.0 125.96463012695312 129.28799438476562 16 +#0f8c0aae-a5ce-47ae-af66-a762f44a9d3a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.02025 0.0 0.0 115.89058685302734 116.44599914550781 61 +22102 GGAAA 5 0.032529999999999996 0.0 0.0 123.7591552734375 123.37649536132812 98 +#43000cf1-c697-4e0b-8414-5aed3db85976 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00863 0.0 0.0 115.45061492919922 115.2125015258789 26 +22102 GGAAA 5 0.03153 0.0 0.0 123.54806518554688 124.41400146484375 95 +#1a0779f0-4d51-4400-8b0e-29363ea9aa91 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00332 0.0 0.0 121.51219177246094 122.51849365234375 10 +22102 GGAAA 1 0.00664 0.0 0.0 127.57340240478516 126.875 20 +#85462d40-9227-4f0a-ad25-c4c5abb6b7e6 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00232 0.0 0.0 118.0605697631836 117.97699737548828 7 +22102 GGAAA 3 0.01792 0.0 0.0 125.30520629882812 124.95249938964844 54 +#5bf2cef1-ec1f-4b1f-bf9f-e79dccb33836 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01129 0.0 0.0 123.4063491821289 123.86349487304688 34 +22102 GGAAA 6 0.03785 0.0 0.0 127.39415740966797 127.95649719238281 114 +#db70549e-4650-4e64-904d-7929f4701b4d chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00896 0.0 0.0 113.59844970703125 113.57099914550781 27 +22102 GGAAA 2 0.02922 0.0 0.0 123.96391296386719 123.3489990234375 88 +#34c8247e-6fbd-4a8c-a17e-8c740d3bfb08 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.02623 0.0 0.0 116.989013671875 117.33599853515625 79 +22102 GGAAA 4 0.05378 0.0 0.0 128.04013061523438 128.47850036621094 162 +#0eb8f174-1680-41ca-a098-b762e6ee7b76 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.017589999999999998 0.0 0.0 121.86357879638672 121.02200317382812 53 +22102 GGAAA 5 0.030549999999999997 0.0 0.0 120.92530059814453 122.95249938964844 92 +#77489463-5e96-43b5-ba97-aad51f918336 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.01726 0.0 0.0 115.67981719970703 115.3905029296875 52 +22102 GGAAA 7 0.04051 0.0 0.0 125.22063446044922 126.13650512695312 122 +#4e6ece57-2cb1-4f12-8410-ae9696be4e43 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.01494 0.0 0.0 118.05428314208984 119.79900360107422 45 +22102 GGAAA 3 0.01594 0.00299 0.0 122.89998626708984 121.07949829101562 48 +#578c1cbf-e9c0-47b0-b5ad-eeeec8cacaa2 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00232 0.0 0.0 112.2434310913086 111.82099914550781 7 +22102 GGAAA 5 0.02323 0.0 0.0 124.31827545166016 124.66299438476562 70 +#ff72f771-8174-4950-9ede-40ffb052d044 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0249 0.0 0.0 125.5434799194336 125.35199737548828 75 +22102 GGAAA 1 0.00299 0.0 0.0 123.20488739013672 123.60900115966797 9 +#97b0f9b2-48c6-4928-b366-b1e7b8721271 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00697 0.0 0.0 110.35895538330078 110.57499694824219 21 +22102 GGAAA 1 0.01959 0.0 0.0 123.4191665649414 123.74299621582031 59 +#136f4584-fa85-47b5-965d-2bc88fa15e4a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00531 0.0 0.0 124.88868713378906 124.70849609375 16 +22102 GGAAA 3 0.027880000000000002 0.0 0.0 125.20147705078125 126.15149688720703 84 +#8a7c1cbe-453b-44a4-82aa-ad2305025760 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00664 0.0 0.0 124.76188659667969 126.17649841308594 20 +22102 GGAAA 3 0.02225 0.0 0.0 124.54386138916016 125.24800109863281 67 +#a77db53e-9553-4045-858a-9953b6a42523 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00465 0.0 0.0 119.87113952636719 118.6865005493164 14 +22102 GGAAA 1 0.01926 0.0 0.0 124.49884796142578 124.62000274658203 58 +#085929b9-c69c-4245-99dc-de3e01b24557 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.01593 0.0 0.0 119.85005950927734 119.84649658203125 48 +22102 GGAAA 6 0.037169999999999995 0.0 0.0 123.7125473022461 125.9010009765625 112 +#b03e37d7-1199-43e4-ad8e-90d5f65484ba chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01793 0.0 0.0 121.78507232666016 122.52549743652344 54 +22102 GGAAA 4 0.02224 0.0 0.0 122.82258605957031 125.08599853515625 67 +#66e23a5c-4fde-4b66-9b25-ff5bade5ebf6 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0093 0.0 0.0 126.21585845947266 126.08549499511719 28 +22102 GGAAA 3 0.027889999999999998 0.0 0.0 123.52474212646484 123.28099822998047 84 +#7931a9dc-02fd-4dfd-a8e1-92d6fe1a2e9a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00664 0.0 0.0 118.2801513671875 118.9739990234375 20 +22102 GGAAA 1 0.00332 0.0 0.0 129.04949951171875 130.56199645996094 10 +#679e2499-ffd9-4d91-bd03-5fa5228fb2b0 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01062 0.0 0.0 110.985595703125 111.28700256347656 32 +22102 GGAAA 1 0.00232 0.0 0.0 113.77471160888672 114.50599670410156 7 +#d6e01353-c2f7-4051-b49d-b77f23df84db chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00697 0.0 0.0 115.85037994384766 113.0459976196289 21 +22102 GGAAA 5 0.0508 0.0 0.0 122.7002944946289 123.38300323486328 153 +#593e8df7-d17f-45dc-97e9-7dd9f17eccc5 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01029 0.0 0.0 117.29468536376953 117.91200256347656 31 +22102 GGAAA 5 0.06407 0.0 0.0 124.26748657226562 123.34200286865234 193 +#6781c476-1d7d-424f-be2f-7272f2293816 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.0073 0.0 0.0 121.75825500488281 123.20500183105469 22 +22102 GGAAA 1 0.00863 0.0 0.0 125.20330047607422 125.80999755859375 26 +#24561b20-06f9-4395-bb5d-06df8c7af304 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00697 0.0 0.0 124.23766326904297 124.52899932861328 21 +22102 GGAAA 2 0.00896 0.0 0.0 120.3904800415039 120.44999694824219 27 +#dc6b006e-8002-4f07-8ec5-e5256be95278 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00199 0.0 0.0 113.41716766357422 113.08300018310547 6 +22102 GGAAA 1 0.00697 0.0 0.0 110.49089813232422 111.22100067138672 21 +#79f6a527-ae56-4f0c-9374-80ec5312d014 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00299 0.0 0.0 114.39022064208984 115.25900268554688 9 +22102 GGAAA 1 0.02025 0.0 0.0 123.9005126953125 123.66100311279297 61 +#da09104c-079f-4258-8c19-7c9d5cc89538 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00764 0.0 0.0 118.37809753417969 115.08300018310547 23 +22102 GGAAA 2 0.01792 0.0 0.0 118.81961059570312 112.66899871826172 54 +#39db71ed-6c5a-4ede-a358-e81f0e6bf313 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00432 0.0 0.0 124.07276153564453 124.88800048828125 13 +22102 GGAAA 4 0.021249999999999998 0.0 0.0 122.57406616210938 124.53500366210938 64 +#36e065cf-3fd1-4960-a8fb-e49eab5350c1 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.02125 0.0 0.0 114.66856384277344 114.3759994506836 64 +22102 GGAAA 4 0.02192 0.0 0.0 126.02337646484375 126.36900329589844 66 +#4f330c34-6e05-41aa-b867-90bbd125e829 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01295 0.0 0.0 122.01708984375 122.65399932861328 39 +22102 GGAAA 7 0.06972 0.00764 0.0 123.195068359375 124.55599975585938 210 +#5454e135-40bd-416c-836f-78c02e508a3c chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 5 0.02954 0.0 0.0 120.00120544433594 120.44499969482422 89 +22102 GGAAA 1 0.00896 0.0 0.0 124.81151580810547 126.86799621582031 27 +#539baf2c-e615-463f-950e-938f9370f66d chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00697 0.0 0.0 122.3088150024414 122.6449966430664 21 +22102 GGAAA 2 0.0069700000000000005 0.0 0.0 119.58319091796875 121.76200103759766 21 +#082d338f-2d9d-48da-9308-9031ffc98e33 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.01129 0.0 0.0 120.01493835449219 119.44950103759766 34 +22102 GGAAA 2 0.0083 0.0 0.0 122.33280181884766 123.35900115966797 25 +#905dc486-7e27-423d-bd9e-1ef91f051f5e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0093 0.0 0.0 121.48035430908203 122.12300109863281 28 +22102 GGAAA 4 0.017929999999999998 0.00332 0.0 126.76508331298828 130.45199584960938 54 +#2e0984c3-ab2e-4f67-bcdf-2f83731e9b33 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00963 0.0 0.0 120.62188720703125 120.8550033569336 29 +22102 GGAAA 2 0.00431 0.00232 0.0 128.32029724121094 127.6259994506836 13 +#ca36cae0-9b99-4bc7-b542-5ceafd7fe08e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00232 0.0 0.0 120.32000732421875 120.10199737548828 7 +22102 GGAAA 1 0.01527 0.0 0.0 126.6950454711914 127.17149353027344 46 +#20efbede-e82d-497d-837a-a504f23daa7a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00398 0.0 0.0 112.75125885009766 112.59500122070312 12 +22102 GGAAA 1 0.00299 0.0 0.0 122.87911224365234 125.55000305175781 9 +#e33453d3-70da-4985-b718-581993fffe54 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00332 0.0 0.0 124.25199127197266 125.18699645996094 10 +22102 GGAAA 2 0.02889 0.0 0.0 121.79318237304688 123.06199645996094 87 +#3bcf4483-16f3-4ad3-9109-67138290cca3 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.00731 0.0 0.0 119.68036651611328 120.87349700927734 22 +22102 GGAAA 1 0.01029 0.0 0.0 121.55876922607422 121.3010025024414 31 +#7bb71d53-9b4a-4571-83f3-2aebd1fcbac1 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.01892 0.0 0.0 120.60784149169922 120.17900085449219 57 +22102 GGAAA 4 0.01361 0.0 0.0 122.4340591430664 123.13600158691406 41 +#501e4486-c0c2-4d1f-938b-af2449132fb0 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00498 0.0 0.0 122.9534683227539 122.7490005493164 15 +22102 GGAAA 2 0.0166 0.0 0.0 122.6683578491211 124.07249450683594 50 +#7e6a64b0-7d43-4f78-a72c-d053eaac2b71 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.01693 0.0 0.0 114.24336242675781 113.62000274658203 51 +22102 GGAAA 4 0.01129 0.0 0.0 124.12264251708984 124.63099670410156 34 +#8b682e72-00ee-4a1a-98bf-362841494e57 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01494 0.0 0.0 121.48255920410156 120.88600158691406 45 +22102 GGAAA 8 0.05246 0.0 0.0 124.7437973022461 125.19549560546875 158 +#be2461c2-1165-47fc-ba73-2aadcfa12b5f chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00896 0.0 0.0 119.70619201660156 120.0780029296875 27 +22102 GGAAA 1 0.00232 0.0 0.0 129.27142333984375 128.3769989013672 7 +#c395d12e-07b3-4a1d-88cc-d3f7a8603d64 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.00863 0.0 0.0 119.27664947509766 119.33699798583984 26 +22102 GGAAA 3 0.011290000000000001 0.0 0.0 122.20012664794922 121.69549560546875 34 +#af037c78-1908-4828-8e39-481c69de7afc chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.02357 0.0 0.0 115.24366760253906 115.1719970703125 71 +22102 GGAAA 3 0.01328 0.0 0.0 124.0596923828125 124.27850341796875 40 +#d1262e2d-f7d5-4afc-8e66-98c77bdf21b7 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.023239999999999997 0.0 0.0 114.12039947509766 113.22699737548828 70 +22102 GGAAA 4 0.05013 0.0 0.0 123.6082763671875 123.87899780273438 151 +#6b779e7d-26fb-4863-9082-04068823a29d chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00863 0.0 0.0 125.01396179199219 124.99749755859375 26 +22102 GGAAA 1 0.00232 0.0 0.0 133.4332733154297 134.6649932861328 7 +#e8da2741-03f5-416a-a7f0-96250a49ddd6 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.02358 0.0 0.0 122.79644775390625 122.7229995727539 71 +22102 GGAAA 9 0.04183 0.0 0.0 123.63143920898438 124.23600006103516 126 +#484f63e8-a501-4edd-8c0e-fba261ed96e1 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00764 0.0 0.0 118.35243225097656 120.302001953125 23 +22102 GGAAA 2 0.01095 0.0 0.0 126.8102035522461 126.19499969482422 33 +#0f18df3d-e006-4d83-9c00-d2b6e2b668af chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00896 0.0 0.0 123.11996459960938 123.06900024414062 27 +22102 GGAAA 1 0.00631 0.0 0.0 129.66537475585938 131.13299560546875 19 +#a7b0744a-4f4a-4d45-907d-b0eed99d2e98 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00598 0.0 0.0 118.61209869384766 117.44599914550781 18 +22102 GGAAA 2 0.01726 0.0 0.0 124.54773712158203 125.95449829101562 52 +#30f0513c-dc44-44d4-ac18-1bfd7a9a28bb chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00996 0.0 0.0 115.39576721191406 114.21499633789062 30 +22102 GGAAA 6 0.03054 0.0 0.0 124.31990051269531 125.22949981689453 92 +#6057e4db-745d-407d-98bb-83a8e9a5f0ce chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.04349 0.0 0.0 113.60332489013672 113.35299682617188 131 +22102 GGAAA 5 0.05743 0.0 0.0 120.23699188232422 121.44599914550781 173 +#55fb9fbe-c25a-486b-9fed-b50328c70e5a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22102 GGAAA 1 0.00631 0.0 0.0 127.09893798828125 128.00999450683594 19 +#
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/sample1.tsv.idx Tue May 05 06:57:10 2020 -0400 @@ -0,0 +1,60 @@ +ref_id ref_start ref_end read_id kmers dwell_time NNNNN_kmers mismatch_kmers missing_kmers byte_offset byte_len +chr 22101 22103 f30a0489-ec1e-4f6e-829e-fa6d16dbee2e 2 0.01228 0 0 0 0 282 +chr 22101 22103 e924b30f-22dc-4156-8e5c-ba664abbe7a7 2 0.0322 0 0 0 283 280 +chr 22101 22103 d4988330-6f34-498a-b1e3-6574d8b3dae2 2 0.025559999999999996 0 0 0 564 295 +chr 22101 22103 0f8c0aae-a5ce-47ae-af66-a762f44a9d3a 2 0.052779999999999994 0 0 0 860 295 +chr 22101 22103 43000cf1-c697-4e0b-8414-5aed3db85976 2 0.04016 0 0 0 1156 282 +chr 22101 22103 1a0779f0-4d51-4400-8b0e-29363ea9aa91 2 0.00996 0 0 0 1439 272 +chr 22101 22103 85462d40-9227-4f0a-ad25-c4c5abb6b7e6 2 0.020239999999999998 0 0 0 1712 281 +chr 22101 22103 5bf2cef1-ec1f-4b1f-bf9f-e79dccb33836 2 0.04914 0 0 0 1994 283 +chr 22101 22103 db70549e-4650-4e64-904d-7929f4701b4d 2 0.03818 0 0 0 2278 282 +chr 22101 22103 34c8247e-6fbd-4a8c-a17e-8c740d3bfb08 2 0.08001 0 0 0 2561 282 +chr 22101 22103 0eb8f174-1680-41ca-a098-b762e6ee7b76 2 0.048139999999999995 0 0 0 2844 309 +chr 22101 22103 77489463-5e96-43b5-ba97-aad51f918336 2 0.05777 0 0 0 3154 283 +chr 22101 22103 4e6ece57-2cb1-4f12-8410-ae9696be4e43 2 0.030879999999999998 1 0 0 3438 287 +chr 22101 22103 578c1cbf-e9c0-47b0-b5ad-eeeec8cacaa2 2 0.02555 0 0 0 3726 281 +chr 22101 22103 ff72f771-8174-4950-9ede-40ffb052d044 2 0.027889999999999998 0 0 0 4008 280 +chr 22101 22103 97b0f9b2-48c6-4928-b366-b1e7b8721271 2 0.02656 0 0 0 4289 282 +chr 22101 22103 136f4584-fa85-47b5-965d-2bc88fa15e4a 2 0.033190000000000004 0 0 0 4572 293 +chr 22101 22103 8a7c1cbe-453b-44a4-82aa-ad2305025760 2 0.02889 0 0 0 4866 283 +chr 22101 22103 a77db53e-9553-4045-858a-9953b6a42523 2 0.02391 0 0 0 5150 282 +chr 22101 22103 085929b9-c69c-4245-99dc-de3e01b24557 2 0.053099999999999994 0 0 0 5433 295 +chr 22101 22103 b03e37d7-1199-43e4-ad8e-90d5f65484ba 2 0.04017 0 0 0 5729 283 +chr 22101 22103 66e23a5c-4fde-4b66-9b25-ff5bade5ebf6 2 0.03719 0 0 0 6013 295 +chr 22101 22103 7931a9dc-02fd-4dfd-a8e1-92d6fe1a2e9a 2 0.00996 0 0 0 6309 281 +chr 22101 22103 679e2499-ffd9-4d91-bd03-5fa5228fb2b0 2 0.01294 0 0 0 6591 280 +chr 22101 22103 d6e01353-c2f7-4051-b49d-b77f23df84db 2 0.057769999999999995 0 0 0 6872 281 +chr 22101 22103 593e8df7-d17f-45dc-97e9-7dd9f17eccc5 2 0.07436000000000001 0 0 0 7154 284 +chr 22101 22103 6781c476-1d7d-424f-be2f-7272f2293816 2 0.01593 0 0 0 7439 282 +chr 22101 22103 24561b20-06f9-4395-bb5d-06df8c7af304 2 0.01593 0 0 0 7722 282 +chr 22101 22103 dc6b006e-8002-4f07-8ec5-e5256be95278 2 0.00896 0 0 0 8005 282 +chr 22101 22103 79f6a527-ae56-4f0c-9374-80ec5312d014 2 0.02324 0 0 0 8288 281 +chr 22101 22103 da09104c-079f-4258-8c19-7c9d5cc89538 2 0.02556 0 0 0 8570 283 +chr 22101 22103 39db71ed-6c5a-4ede-a358-e81f0e6bf313 2 0.02557 0 0 0 8854 296 +chr 22101 22103 36e065cf-3fd1-4960-a8fb-e49eab5350c1 2 0.04317 0 0 0 9151 282 +chr 22101 22103 4f330c34-6e05-41aa-b867-90bbd125e829 2 0.08267000000000001 1 0 0 9434 283 +chr 22101 22103 5454e135-40bd-416c-836f-78c02e508a3c 2 0.0385 0 0 0 9718 283 +chr 22101 22103 539baf2c-e615-463f-950e-938f9370f66d 2 0.013940000000000001 0 0 0 10002 295 +chr 22101 22103 082d338f-2d9d-48da-9308-9031ffc98e33 2 0.01959 0 0 0 10298 282 +chr 22101 22103 905dc486-7e27-423d-bd9e-1ef91f051f5e 2 0.027229999999999997 1 0 0 10581 299 +chr 22101 22103 2e0984c3-ab2e-4f67-bcdf-2f83731e9b33 2 0.01394 1 0 0 10881 285 +chr 22101 22103 ca36cae0-9b99-4bc7-b542-5ceafd7fe08e 2 0.01759 0 0 0 11167 281 +chr 22101 22103 20efbede-e82d-497d-837a-a504f23daa7a 2 0.0069700000000000005 0 0 0 11449 282 +chr 22101 22103 e33453d3-70da-4985-b718-581993fffe54 2 0.03221 0 0 0 11732 283 +chr 22101 22103 3bcf4483-16f3-4ad3-9109-67138290cca3 2 0.0176 0 0 0 12016 282 +chr 22101 22103 7bb71d53-9b4a-4571-83f3-2aebd1fcbac1 2 0.03253 0 0 0 12299 282 +chr 22101 22103 501e4486-c0c2-4d1f-938b-af2449132fb0 2 0.021580000000000002 0 0 0 12582 279 +chr 22101 22103 7e6a64b0-7d43-4f78-a72c-d053eaac2b71 2 0.028220000000000002 0 0 0 12862 283 +chr 22101 22103 8b682e72-00ee-4a1a-98bf-362841494e57 2 0.0674 0 0 0 13146 283 +chr 22101 22103 be2461c2-1165-47fc-ba73-2aadcfa12b5f 2 0.011279999999999998 0 0 0 13430 280 +chr 22101 22103 c395d12e-07b3-4a1d-88cc-d3f7a8603d64 2 0.01992 0 0 0 13711 296 +chr 22101 22103 af037c78-1908-4828-8e39-481c69de7afc 2 0.03685 0 0 0 14008 281 +chr 22101 22103 d1262e2d-f7d5-4afc-8e66-98c77bdf21b7 2 0.07336999999999999 0 0 0 14290 296 +chr 22101 22103 6b779e7d-26fb-4863-9082-04068823a29d 2 0.010950000000000001 0 0 0 14587 280 +chr 22101 22103 e8da2741-03f5-416a-a7f0-96250a49ddd6 2 0.06541 0 0 0 14868 283 +chr 22101 22103 484f63e8-a501-4edd-8c0e-fba261ed96e1 2 0.01859 0 0 0 15152 280 +chr 22101 22103 0f18df3d-e006-4d83-9c00-d2b6e2b668af 2 0.015269999999999999 0 0 0 15433 283 +chr 22101 22103 a7b0744a-4f4a-4d45-907d-b0eed99d2e98 2 0.02324 0 0 0 15717 283 +chr 22101 22103 30f0513c-dc44-44d4-ac18-1bfd7a9a28bb 2 0.0405 0 0 0 16001 283 +chr 22101 22103 6057e4db-745d-407d-98bb-83a8e9a5f0ce 2 0.10092000000000001 0 0 0 16285 285 +chr 22102 22103 55fb9fbe-c25a-486b-9fed-b50328c70e5a 1 0.00631 0 0 0 16571 212
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/sample2.tsv Tue May 05 06:57:10 2020 -0400 @@ -0,0 +1,401 @@ +#7f1aeec8-0acc-4a78-8ff2-12116de7906f chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00531 0.0 0.0 121.67037963867188 121.23699951171875 16 +22102 GGAAA 4 0.01892 0.0 0.0 124.56398010253906 124.41100311279297 57 +#3fb36f87-41a9-4053-bba0-e9c99c0f3af4 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00764 0.0 0.0 117.99856567382812 118.55400085449219 23 +22102 GGAAA 4 0.01693 0.0 0.0 124.62902069091797 125.23799896240234 51 +#d6da51fb-29a9-4f08-a538-ad7a52d6e1e2 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01228 0.0 0.0 123.177734375 123.62699890136719 37 +22102 GGAAA 5 0.02124 0.0 0.0 120.51213836669922 123.08799743652344 64 +#833fd518-978e-4044-8640-a9d7c95c4783 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0073 0.0 0.0 123.09036254882812 123.49099731445312 22 +22102 GGAAA 2 0.00697 0.0 0.0 124.90296173095703 125.5459976196289 21 +#1c883a73-b331-4419-b280-d153eb932ba5 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.034870000000000005 0.0 0.0 122.48480987548828 122.57599639892578 105 +22102 GGAAA 3 0.022899999999999997 0.0 0.0 125.73690795898438 125.30000305175781 69 +#4b24388e-8804-421d-a416-6e84f24b437d chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00797 0.0 0.0 113.0198745727539 112.69200134277344 24 +22102 GGAAA 1 0.01195 0.0 0.0 123.59333038330078 123.98100280761719 36 +#0a1578b4-b82c-48c3-934b-803f4bc9cb7e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00664 0.0 0.0 120.83223724365234 121.28500366210938 20 +22102 GGAAA 1 0.00365 0.0 0.0 125.82282257080078 124.02899932861328 11 +#27085b2d-47a1-4eb2-a6fe-d56385977a83 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.01959 0.0 0.0 117.96282196044922 119.27300262451172 59 +22102 GGAAA 2 0.00796 0.0 0.0 122.18533325195312 123.54949951171875 24 +#480de004-a586-4af7-b622-a805c27d079f chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.00597 0.0 0.0 122.96639251708984 122.85050201416016 18 +22102 GGAAA 1 0.02092 0.0 0.0 124.03636169433594 125.01100158691406 63 +#2e873328-dcad-4a50-a7bf-d1df635ea4ae chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00863 0.0 0.0 121.93891906738281 121.90950012207031 26 +22102 GGAAA 1 0.01062 0.0 0.0 125.28668212890625 123.88850402832031 32 +#f15e9f80-aeba-4e3f-af6e-af9844913cd5 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.00963 0.0 0.0 120.74498748779297 120.75499725341797 29 +22102 GGAAA 6 0.05378 0.0 0.0 122.99015045166016 124.61299896240234 162 +#30636390-aa9f-44d3-a266-93e4e2678473 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.030539999999999998 0.0 0.0 120.44935607910156 121.31599426269531 92 +22102 GGAAA 1 0.00299 0.0 0.0 126.57222747802734 126.14600372314453 9 +#d21823f1-8123-4a8c-80d9-405da871be9a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01494 0.0 0.0 113.35908508300781 113.60199737548828 45 +22102 GGAAA 2 0.00963 0.00631 0.0 123.0432357788086 123.51599884033203 29 +#61978e0e-8af4-4cdd-bada-4cf5388a769a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00498 0.0 0.0 117.7689437866211 118.45099639892578 15 +22102 GGAAA 10 0.06774000000000001 0.0 0.0 122.64175415039062 124.68000030517578 204 +#6d7545e1-c6db-4fd2-8ac5-5761352f8ffe chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00996 0.0 0.0 115.277099609375 114.93600463867188 30 +22102 GGAAA 4 0.015279999999999998 0.0 0.0 125.7061996459961 126.9209976196289 46 +#a26d4020-651b-46d6-aea4-992e5ea6240c chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00963 0.0 0.0 122.77800750732422 123.0530014038086 29 +22102 GGAAA 1 0.01926 0.0 0.0 121.49858093261719 122.54499816894531 58 +#1fbca3f2-965c-4125-80f4-20093835e37e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0093 0.0 0.0 120.09568786621094 120.6875 28 +22102 GGAAA 2 0.0093 0.0 0.0 123.17460632324219 124.97599792480469 28 +#310da5d9-d91e-42a9-98e0-edd2faa6c35a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00232 0.0 0.0 116.09685516357422 114.8949966430664 7 +22102 GGAAA 3 0.02291 0.0 0.0 123.7055435180664 125.04399871826172 69 +#a411aab8-428e-4226-88e6-b43ca3867bc6 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.0069700000000000005 0.0 0.0 118.27794647216797 120.37000274658203 21 +22102 GGAAA 1 0.02058 0.0 0.0 122.61747741699219 124.44300079345703 62 +#de113ee4-1dba-4944-a316-2ca1fce725c4 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00764 0.0 0.0 119.49696350097656 118.93800354003906 23 +22102 GGAAA 2 0.00763 0.0 0.0 127.0856704711914 127.45600128173828 23 +#d6bed947-c3a4-40a5-924c-b7d1819be0c9 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00299 0.0 0.0 124.054443359375 124.02100372314453 9 +22102 GGAAA 2 0.01859 0.0 0.0 124.58502960205078 124.77349853515625 56 +#5b6891eb-2494-4bf8-9c17-f8571560d4fb chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.02889 0.0 0.0 116.65760040283203 117.64900207519531 87 +22102 GGAAA 2 0.01694 0.0 0.0 124.21409606933594 124.2959976196289 51 +#3f102f7e-1248-4711-8f7d-00c52db6d5fc chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.01029 0.0 0.0 115.38471984863281 113.75 31 +22102 GGAAA 8 0.041819999999999996 0.0 0.0 122.25516510009766 123.08300018310547 126 +#181d2b5d-74e6-4c68-a6c9-324089b7f240 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00199 0.0 0.0 110.49484252929688 106.01950073242188 6 +22102 GGAAA 3 0.011949999999999999 0.0 0.0 120.17435455322266 123.89550018310547 36 +#86be4133-d483-44bd-b5c2-6909afc50eae chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00498 0.0 0.0 118.86853790283203 120.5770034790039 15 +22102 GGAAA 1 0.0166 0.0 0.0 125.48129272460938 125.49299621582031 50 +#1772961d-b04e-464e-8ed3-4899924ef650 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.0176 0.0 0.0 119.79141235351562 120.39399719238281 53 +22102 GGAAA 4 0.03485 0.0 0.0 122.99738311767578 124.11299896240234 105 +#c8d56420-ad47-4d46-85a7-dc12f7e026ad chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01361 0.0 0.0 121.38304901123047 122.072998046875 41 +22102 GGAAA 2 0.03121 0.0 0.0 123.4777603149414 125.11499786376953 94 +#2baae8e2-eae6-4772-afb0-ad461eddf0f3 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.02191 0.0 0.0 112.87773895263672 112.31849670410156 66 +22102 GGAAA 6 0.048139999999999995 0.0 0.0 123.20703125 123.47200012207031 145 +#81157c06-2ff9-4258-af13-32e687dbb5a2 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.012289999999999999 0.0 0.0 120.21159362792969 121.0009994506836 37 +22102 GGAAA 1 0.01262 0.0 0.0 124.30326080322266 125.03199768066406 38 +#cd18f101-5eb1-42f0-8b56-b6352f1ba69e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01062 0.0 0.0 122.727783203125 121.71600341796875 32 +22102 GGAAA 1 0.01959 0.0 0.0 120.3940200805664 120.60700225830078 59 +#c213db3c-0250-43a5-bf8d-6f95cf17644c chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.01294 0.0 0.0 120.97591400146484 120.86499786376953 39 +22102 GGAAA 3 0.020249999999999997 0.0 0.0 124.69209289550781 124.89800262451172 61 +#981b494a-df51-42dd-b646-0df070f4efae chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00432 0.0 0.0 122.0478515625 122.28700256347656 13 +22102 GGAAA 1 0.00465 0.0 0.0 111.81329345703125 111.86599731445312 14 +#d2496ef6-c607-40d4-a6b3-b7c2b7871a1e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.028220000000000002 0.0 0.0 121.14704895019531 121.98200225830078 85 +22102 GGAAA 2 0.00697 0.0 0.0 118.77301025390625 120.10600280761719 21 +#9c086e36-4d1c-4d1c-9917-db50c34c945c chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.03453 0.0 0.0 120.37749481201172 121.01799774169922 104 +22102 GGAAA 1 0.00465 0.0 0.0 120.1751480102539 120.29850006103516 14 +#eff0a3fc-6235-4bec-be1a-34ae44096120 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00199 0.0 0.0 118.11365509033203 119.47700500488281 6 +22102 GGAAA 4 0.01593 0.0 0.0 125.0530776977539 125.97799682617188 48 +#0a70340e-9ecd-429a-98f3-26073faa5e29 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.03353 0.0 0.0 123.81767272949219 123.64399719238281 101 +22102 GGAAA 1 0.00797 0.0 0.0 119.3930892944336 119.14500427246094 24 +#d5cc0d32-d080-414c-97f1-2dab62fac7b0 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01494 0.0 0.0 120.5522232055664 120.72799682617188 45 +22102 GGAAA 1 0.00863 0.0 0.0 124.40823364257812 123.53799438476562 26 +#6e1f3278-9f34-4695-b2d6-e29f7c66c6c9 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00465 0.0 0.0 121.79956817626953 122.62750244140625 14 +22102 GGAAA 4 0.01825 0.0 0.0 123.23145294189453 124.75399780273438 55 +#3bbffd17-d7c8-486a-86fd-c10beb04e549 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.03188 0.0 0.0 116.90436553955078 118.60499572753906 96 +22102 GGAAA 1 0.00199 0.0 0.0 126.45266723632812 127.84600067138672 6 +#cb7181c8-3fe4-46cd-86f3-419ed9fc43ea chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00299 0.0 0.0 116.83921813964844 117.69599914550781 9 +22102 GGAAA 1 0.0093 0.0 0.0 123.21795654296875 124.35250091552734 28 +#4b65f723-7a3e-41d2-99b8-b532f33b431d chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.00963 0.0 0.0 115.38372039794922 113.71399688720703 29 +22102 GGAAA 1 0.0083 0.0 0.0 125.73639678955078 126.37999725341797 25 +#34f3b477-fee8-4c5c-9d5e-878d3233c5ac chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00398 0.0 0.0 116.50399780273438 115.82400512695312 12 +22102 GGAAA 1 0.00365 0.0 0.0 124.93991088867188 125.7509994506836 11 +#62955596-a9c8-4aae-80e9-68526b3c61e6 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00863 0.0 0.0 109.37800598144531 109.08450317382812 26 +22102 GGAAA 1 0.00232 0.0 0.0 114.31342315673828 114.87899780273438 7 +#9be5fd79-c56b-43a3-9fcd-a7f99a6e8aa2 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00365 0.0 0.0 118.08637237548828 117.99800109863281 11 +22102 GGAAA 2 0.02124 0.0 0.0 123.51392364501953 124.32949829101562 64 +#bff00f41-c3c5-4f10-8caa-3bfe1221f3a3 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.02457 0.0 0.0 123.35858154296875 123.14199829101562 74 +22102 GGAAA 1 0.00266 0.0 0.0 129.6371307373047 131.89950561523438 8 +#58264997-9ac8-4d8c-8dd5-837e5132646a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01328 0.0 0.0 112.2530746459961 111.28250122070312 40 +22102 GGAAA 4 0.03985 0.0 0.0 122.02442932128906 122.41500091552734 120 +#74838d35-d7a0-4a2e-b5c2-53b68ba407a8 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.02158 0.0 0.0 112.81644439697266 111.77899932861328 65 +22102 GGAAA 3 0.0166 0.0 0.0 124.40725708007812 124.14800262451172 50 +#a0e528ef-2a70-445c-9bed-cf6e93e8c3a8 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00498 0.0 0.0 117.61319732666016 115.46900177001953 15 +22102 GGAAA 5 0.030209999999999997 0.0 0.0 124.89049530029297 125.47200012207031 91 +#9a0198f3-8a28-4724-a36d-4bb7f66e6951 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00498 0.0 0.0 124.09786224365234 124.40299987792969 15 +22102 GGAAA 1 0.01726 0.0 0.0 112.98601531982422 109.63150024414062 52 +#5885e81a-2438-46b9-b688-9b9982f8570a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.02357 0.0 0.0 114.32921600341797 113.5719985961914 71 +22102 GGAAA 1 0.00963 0.0 0.0 123.89031219482422 124.80999755859375 29 +#667bd035-80ca-40f2-b972-9f4407e172e6 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00332 0.0 0.0 120.4215087890625 121.35050201416016 10 +22102 GGAAA 6 0.02922 0.0 0.0 121.31499481201172 122.92399597167969 88 +#3e9c6592-c128-48f5-9612-7dc484b9e44e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0073 0.0 0.0 113.30953979492188 112.24349975585938 22 +22102 GGAAA 1 0.01992 0.0 0.0 121.91053771972656 122.43099975585938 60 +#2fd8c241-c12b-4875-8d0c-c5fc81bb09b9 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00266 0.0 0.0 120.62987518310547 119.20050048828125 8 +22102 GGAAA 3 0.02524 0.0 0.0 125.9267807006836 125.072998046875 76 +#49ec73c1-6e4a-430a-a005-528c84080a97 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01129 0.0 0.0 119.94082641601562 119.76899719238281 34 +22102 GGAAA 5 0.0581 0.0 0.0 121.55810546875 120.93599700927734 175 +#efacaac8-54ba-4a97-a693-f281d840244e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00797 0.0 0.0 115.44463348388672 115.4384994506836 24 +22102 GGAAA 3 0.035519999999999996 0.0 0.0 125.2180404663086 125.09200286865234 107 +#bb314309-4158-4609-87ce-51c2d726bf8c chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01992 0.0 0.0 120.22622680664062 120.79100036621094 60 +22102 GGAAA 3 0.01295 0.0 0.0 122.62750244140625 125.00499725341797 39 +#985fd02c-339f-48f1-84f3-a6b97ec7ea00 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00398 0.0 0.0 120.4280776977539 119.00149536132812 12 +22102 GGAAA 2 0.02324 0.0 0.0 123.06693267822266 122.00499725341797 70 +#05408a96-d1a6-4b61-8db0-33ad56798cf3 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00398 0.0 0.0 118.63642120361328 119.75 12 +22102 GGAAA 1 0.01195 0.0 0.0 124.39945220947266 123.87800598144531 36 +#842c3bbc-b856-49b8-bd6a-2f53af0f7025 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.01892 0.0 0.0 114.64570617675781 115.4800033569336 57 +22102 GGAAA 3 0.014929999999999999 0.0 0.0 127.22561645507812 127.19000244140625 45 +#f5f10a73-9076-4593-9dac-4be9be7acff9 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.01063 0.0 0.0 114.28762817382812 114.34700012207031 32 +22102 GGAAA 5 0.06043 0.0 0.0 123.19096374511719 122.45099639892578 182 +#48e172d4-b919-4a98-864e-b475897444fb chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00764 0.0 0.0 121.75609588623047 120.88400268554688 23 +22102 GGAAA 4 0.01727 0.0 0.0 123.93626403808594 126.46700286865234 52 +#bfd1efac-c38a-4140-8e44-6dd000f28d73 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.02888 0.0 0.0 119.41011047363281 120.16799926757812 87 +22102 GGAAA 3 0.01129 0.0 0.0 122.53277587890625 124.68499755859375 34 +#dc162623-c4b8-4b4a-bbb7-4f9e7112f0ad chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.01162 0.0 0.0 119.62611389160156 120.25700378417969 35 +22102 GGAAA 1 0.0073 0.0 0.0 125.10968780517578 124.38099670410156 22 +#f8f8bfed-8440-4e31-a8cd-cebe450bfa4e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00232 0.0 0.0 126.36258697509766 127.28700256347656 7 +22102 GGAAA 1 0.00764 0.0 0.0 117.92695617675781 120.9729995727539 23 +#c8bea253-ba31-4a0c-af06-7eb37c4a9623 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0073 0.0 0.0 113.8670883178711 114.2239990234375 22 +22102 GGAAA 6 0.027549999999999998 0.0 0.0 124.2974624633789 124.15799713134766 83 +#989d7bda-cedb-42d2-b5e2-c4d17e41efca chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00896 0.0 0.0 119.91421508789062 119.59200286865234 27 +22102 GGAAA 1 0.00498 0.0 0.0 126.19140625 125.49299621582031 15 +#7a23ce30-3227-4e9a-a5ba-1db7bdee9ced chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00465 0.0 0.0 120.05058288574219 120.54450225830078 14 +22102 GGAAA 3 0.01395 0.0 0.0 123.38021850585938 124.989501953125 42 +#dd2f645b-8681-48f0-9b62-4b32e0d7c9be chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00232 0.0 0.0 118.63227844238281 118.29399871826172 7 +22102 GGAAA 2 0.01328 0.00299 0.0 127.2238998413086 127.76000213623047 40 +#b05e5251-cfa8-4288-bf67-5c5410967df8 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00531 0.0 0.0 114.69400024414062 114.52549743652344 16 +22102 GGAAA 6 0.05112 0.0 0.0 124.33245086669922 125.55500030517578 154 +#15c009c3-be67-4bc5-8a6a-23d00002c4b1 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00697 0.0 0.0 113.09381103515625 112.5459976196289 21 +22102 GGAAA 4 0.040510000000000004 0.0 0.0 125.3769760131836 125.98699951171875 122 +#da9b7780-e640-400b-b8c9-6101df31d9a7 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00764 0.0 0.0 116.86439514160156 115.99400329589844 23 +22102 GGAAA 5 0.0146 0.0 0.0 125.28166198730469 124.54750061035156 44 +#22677b8e-1d20-40a9-946c-7539493679ab chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00764 0.0 0.0 114.1315689086914 112.62799835205078 23 +22102 GGAAA 9 0.051460000000000006 0.0 0.0 122.88359069824219 123.25900268554688 155 +#a04813a6-f9a5-40b7-8e76-331b2ebdae49 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01162 0.0 0.0 120.02557373046875 119.88400268554688 35 +22102 GGAAA 3 0.02191 0.0 0.0 124.6802978515625 125.34449768066406 66 +#104a2b7e-3ae3-44ae-8779-c2adeff6c76f chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00398 0.0 0.0 111.1777572631836 110.14350128173828 12 +22102 GGAAA 3 0.01327 0.0 0.0 124.52412414550781 125.97100067138672 40 +#e998fbe2-8c0d-4c5c-bf4f-7185e18ebc07 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01627 0.0 0.0 114.25140380859375 113.31400299072266 49 +22102 GGAAA 1 0.03386 0.0 0.0 118.84562683105469 123.43800354003906 102 +#cb76917c-aa84-4282-ade3-d7375a4e6424 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.0166 0.0 0.0 119.22343444824219 118.53399658203125 50 +22102 GGAAA 3 0.02257 0.0 0.0 124.56883239746094 126.75599670410156 68 +#5a627c4a-2572-4efe-95da-8a3aac4869ea chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00199 0.0 0.0 113.36066436767578 114.01950073242188 6 +22102 GGAAA 1 0.01859 0.0 0.0 115.74459075927734 118.41099548339844 56 +#6ce91c6b-2aa2-4478-a673-e5fd15c6e47b chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00332 0.0 0.0 122.9114990234375 122.49699401855469 10 +22102 GGAAA 1 0.00797 0.0 0.0 120.73748779296875 123.0895004272461 24 +#a4ddc34d-d8cc-4e3d-80cb-f81e72e1f2c8 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01926 0.0 0.0 116.76274871826172 116.78599548339844 58 +22102 GGAAA 4 0.03319 0.0 0.0 125.60735321044922 125.5979995727539 100 +#8c1f3066-b069-4135-a723-b96f36d38a15 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0156 0.0 0.0 116.21473693847656 115.66100311279297 47 +22102 GGAAA 1 0.01693 0.0 0.0 124.2059326171875 123.71800231933594 51 +#c5d34993-bd1a-4b18-a428-d78454cd7ccb chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01195 0.0 0.0 120.46487426757812 119.35200500488281 36 +22102 GGAAA 1 0.00398 0.0 0.0 127.66741943359375 128.31700134277344 12 +#4f01921d-c683-4e85-8597-810c109eb4fd chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01228 0.0 0.0 120.86013793945312 120.5739974975586 37 +22102 GGAAA 5 0.04183 0.0 0.0 123.29005432128906 124.22250366210938 126 +#fcf407e9-9252-4255-af72-61893b319e0f chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.0083 0.0 0.0 115.4833984375 114.96199798583984 25 +22102 GGAAA 3 0.02888 0.0 0.0 125.10005950927734 125.20800018310547 87 +#a9313b9f-c533-4b3f-88bb-1d8e009855f4 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00432 0.0 0.0 122.10530853271484 122.63099670410156 13 +22102 GGAAA 3 0.04216 0.0 0.0 123.6193618774414 123.34300231933594 127 +#e8f7ee19-62e2-4096-95ee-428acd6c366f chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.02058 0.0 0.0 118.2440414428711 118.25399780273438 62 +22102 GGAAA 8 0.028529999999999996 0.0 0.0 122.49427795410156 124.09200286865234 86 +#96781b24-815e-40ad-b2d5-8557fb102427 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.02789 0.0 0.0 122.49520874023438 122.72000122070312 84 +22102 GGAAA 3 0.01261 0.0 0.0 126.70362854003906 127.14100646972656 38 +#554e41cc-2fbf-419d-ba17-421a50fdb706 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00465 0.0 0.0 118.911865234375 119.05000305175781 14 +22102 GGAAA 4 0.042499999999999996 0.0 0.0 124.17623901367188 124.5510025024414 128 +#11a7069d-f176-41a3-a1af-799a2115de20 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.0166 0.0 0.0 118.78388977050781 118.46099853515625 50 +22102 GGAAA 1 0.01627 0.0 0.0 123.67282104492188 124.55000305175781 49 +#ccf05612-40af-4cdb-a7dd-940c9129d4f3 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 3 0.01859 0.0 0.0 114.39768981933594 114.64700317382812 56 +22102 GGAAA 6 0.06108 0.0 0.0 122.79985046386719 122.40299987792969 184 +#46b7c4ff-9ab5-40c8-9792-d7523178afbc chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00564 0.0 0.0 121.00617218017578 120.33799743652344 17 +22102 GGAAA 2 0.015279999999999998 0.0 0.0 125.62187957763672 124.88099670410156 46 +#cabb84ef-c6c0-4e07-beff-e5eed05198d5 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00398 0.0 0.0 121.41592407226562 121.20050048828125 12 +22102 GGAAA 2 0.01826 0.0 0.0 118.0160903930664 121.2760009765625 55 +#caeb4080-a076-4b28-87ff-71c109ccfc8e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01793 0.0 0.0 118.19371795654297 118.68350219726562 54 +22102 GGAAA 2 0.010620000000000001 0.0 0.0 126.31681823730469 126.3699951171875 32 +#c2d50882-3d64-4dd0-895e-017e2c40782e chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00465 0.0 0.0 116.38756561279297 116.92999267578125 14 +22102 GGAAA 6 0.03087 0.0 0.0 125.23326873779297 125.06199645996094 93 +#7e834f65-217d-4f76-9294-99bcb7319211 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.01062 0.0 0.0 113.27202606201172 114.08000183105469 32 +22102 GGAAA 1 0.00199 0.0 0.0 108.19467163085938 108.24749755859375 6 +#ee04c7b7-669f-4d84-a589-63e8195cd11d chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00232 0.0 0.0 119.85729217529297 119.68800354003906 7 +22102 GGAAA 6 0.06506999999999999 0.0 0.0 123.23933410644531 124.06050109863281 196 +#df7fde92-d62a-480d-a573-5568a21baf4a chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.0069700000000000005 0.0 0.0 115.64581298828125 114.62200164794922 21 +22102 GGAAA 1 0.04615 0.0 0.0 120.60552215576172 122.14099884033203 139 +#7e7c3159-d7ba-415c-aafd-5b6101cce083 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 4 0.02457 0.0 0.0 117.3227310180664 116.90249633789062 74 +22102 GGAAA 5 0.024239999999999998 0.0 0.0 127.60884094238281 128.68699645996094 73 +#2ead04b2-a520-4623-bed1-c58b2de4ad13 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.00996 0.0 0.0 123.75735473632812 123.76800537109375 30 +22102 GGAAA 1 0.0073 0.0 0.0 124.35718536376953 125.03250122070312 22 +#1b7e8d9c-dbc7-4131-87da-76ab5c31cef5 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 2 0.02922 0.0 0.0 121.81069946289062 120.7969970703125 88 +22102 GGAAA 1 0.00365 0.0 0.0 128.2813720703125 129.61500549316406 11 +#44f13b68-e386-4e9c-ba0d-eb9b8afe07a4 chr +ref_pos ref_kmer num_events dwell_time NNNNN_dwell_time mismatch_dwell_time mean median num_signals +22101 AGGAA 1 0.00498 0.0 0.0 115.5508041381836 115.84200286865234 15 +22102 GGAAA 3 0.04747 0.0 0.0 123.99502563476562 124.28800201416016 143 +#
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/sample2.tsv.idx Tue May 05 06:57:10 2020 -0400 @@ -0,0 +1,101 @@ +ref_id ref_start ref_end read_id kmers dwell_time NNNNN_kmers mismatch_kmers missing_kmers byte_offset byte_len +chr 22101 22103 7f1aeec8-0acc-4a78-8ff2-12116de7906f 2 0.024229999999999998 0 0 0 0 283 +chr 22101 22103 3fb36f87-41a9-4053-bba0-e9c99c0f3af4 2 0.02457 0 0 0 284 283 +chr 22101 22103 d6da51fb-29a9-4f08-a538-ad7a52d6e1e2 2 0.033519999999999994 0 0 0 568 278 +chr 22101 22103 833fd518-978e-4044-8640-a9d7c95c4783 2 0.01427 0 0 0 847 281 +chr 22101 22103 1c883a73-b331-4419-b280-d153eb932ba5 2 0.05777 0 0 0 1129 310 +chr 22101 22103 4b24388e-8804-421d-a416-6e84f24b437d 2 0.01992 0 0 0 1440 282 +chr 22101 22103 0a1578b4-b82c-48c3-934b-803f4bc9cb7e 2 0.01029 0 0 0 1723 283 +chr 22101 22103 27085b2d-47a1-4eb2-a6fe-d56385977a83 2 0.027549999999999998 0 0 0 2007 283 +chr 22101 22103 480de004-a586-4af7-b622-a805c27d079f 2 0.02689 0 0 0 2291 283 +chr 22101 22103 2e873328-dcad-4a50-a7bf-d1df635ea4ae 2 0.01925 0 0 0 2575 283 +chr 22101 22103 f15e9f80-aeba-4e3f-af6e-af9844913cd5 2 0.06341 0 0 0 2859 284 +chr 22101 22103 30636390-aa9f-44d3-a266-93e4e2678473 2 0.03353 0 0 0 3144 295 +chr 22101 22103 d21823f1-8123-4a8c-80d9-405da871be9a 2 0.02457 1 0 0 3440 286 +chr 22101 22103 61978e0e-8af4-4cdd-bada-4cf5388a769a 2 0.07272 0 0 0 3727 296 +chr 22101 22103 6d7545e1-c6db-4fd2-8ac5-5761352f8ffe 2 0.02524 0 0 0 4024 292 +chr 22101 22103 a26d4020-651b-46d6-aea4-992e5ea6240c 2 0.02889 0 0 0 4317 282 +chr 22101 22103 1fbca3f2-965c-4125-80f4-20093835e37e 2 0.0186 0 0 0 4600 271 +chr 22101 22103 310da5d9-d91e-42a9-98e0-edd2faa6c35a 2 0.02523 0 0 0 4872 280 +chr 22101 22103 a411aab8-428e-4226-88e6-b43ca3867bc6 2 0.02755 0 0 0 5153 297 +chr 22101 22103 de113ee4-1dba-4944-a316-2ca1fce725c4 2 0.015269999999999999 0 0 0 5451 282 +chr 22101 22103 d6bed947-c3a4-40a5-924c-b7d1819be0c9 2 0.02158 0 0 0 5734 280 +chr 22101 22103 5b6891eb-2494-4bf8-9c17-f8571560d4fb 2 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