# HG changeset patch # User iuc # Date 1571164547 14400 # Node ID c2656b729ee951c47187dccd822e35d0cfc72a10 # Parent 19793eecc9f0e33c5b21de2c66438793d3f409c8 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/blob/master/tools/tb-profiler commit a51548708ea975c0a7b135a2cbaa5d094f3c5602" diff -r 19793eecc9f0 -r c2656b729ee9 macros.xml --- a/macros.xml Fri Aug 16 16:26:31 2019 -0400 +++ b/macros.xml Tue Oct 15 14:35:47 2019 -0400 @@ -1,3 +1,3 @@ - 2.6 + 2.6.1 diff -r 19793eecc9f0 -r c2656b729ee9 tb_profiler_profile.xml --- a/tb_profiler_profile.xml Fri Aug 16 16:26:31 2019 -0400 +++ b/tb_profiler_profile.xml Tue Oct 15 14:35:47 2019 -0400 @@ -41,6 +41,7 @@ --threads "\${GALAXY_SLOTS:-1}" #if $advanced.options == 'yes' + '${advanced.call_whole_genome}' --call_method '${advanced.call_method}' --min_gene_frac '${advanced.min_gene_frac}' --mapper '${advanced.mapper}' @@ -58,7 +59,7 @@ #if str($fastq_or_bam.input_select) != "bam" && mv bam/tbprofiler.bam '${output_bam}' #end if - && bcftools view -Ov -o'${output_vcf}' vcf/tbprofiler.targets.csq.bcf + && bcftools view -Ov -o'${output_vcf}' vcf/tbprofiler.targets.csq.vcf.gz #if $output_format == "pdf" && mv results/tbprofiler.results.pdf '${output_pdf}' #else if $output_format == "txt" @@ -109,6 +110,8 @@ + @@ -173,7 +176,7 @@ Summary ======= -The pipeline aligns reads to the H37Rv reference using bowtie2, BWA or minimap2 and then calls variants using SAMtools. These variants are then compared to a drug-resistance database. We also predict the number of reads supporting drug resistance variants as an insight into hetero-resistance (not applicable for minION data). +The pipeline aligns reads to the H37Rv reference using bowtie2, BWA or minimap2 and then calls variants using GATK. These variants are then compared to a drug-resistance database. We also predict the number of reads supporting drug resistance variants as an insight into hetero-resistance (not applicable for minION data). Produces a JSON output file by default.