# HG changeset patch # User iuc # Date 1621703413 0 # Node ID e1a9d6fd258d1420ec1672227ee6a68e502643d2 # Parent 037a116821767eb437caa101726ae375ac81ddc0 "planemo upload for repository https://github.com/galaxyproject/tools-iuc/blob/master/tools/tb-profiler commit 9fa7ac6aaaf97db392a1bf93741a6d271b619ed3" diff -r 037a11682176 -r e1a9d6fd258d macros.xml --- a/macros.xml Wed Jan 06 14:42:20 2021 +0000 +++ /dev/null Thu Jan 01 00:00:00 1970 +0000 @@ -1,3 +0,0 @@ - - 2.8.14 - diff -r 037a11682176 -r e1a9d6fd258d tb_profiler_profile.xml --- a/tb_profiler_profile.xml Wed Jan 06 14:42:20 2021 +0000 +++ b/tb_profiler_profile.xml Sat May 22 17:10:13 2021 +0000 @@ -1,7 +1,7 @@ - + Infer strain types and drug resistance markers from sequences - macros.xml + 3.0.4 tb-profiler @@ -91,7 +91,7 @@ - + @@ -128,7 +128,7 @@ - + @@ -136,14 +136,14 @@ - + - + @@ -151,14 +151,14 @@ - + - + @@ -169,7 +169,7 @@ - + @@ -181,19 +181,15 @@ Summary ======= -The pipeline aligns reads to the H37Rv reference using bowtie2, BWA or minimap2 and then calls variants using GATK. These variants are then compared to a drug-resistance database. We also predict the number of reads supporting drug resistance variants as an insight into hetero-resistance (not applicable for minION data). +The pipeline aligns reads to the H37Rv reference using BWA, bowtie2 or minimap2 and then calls variants +(using bcftools, GATK4 or freebayes). These variants are then compared to a drug-resistance database. +TB-Profiler also predicts the number of reads supporting drug resistance variants as an insight into +hetero-resistance (not applicable for MinION data). Produces a JSON output file by default. ]]> - -@UNPUBLISHED{Phelan2016, - author = {Phelan, Jody}, - title = {TBProfiler}, - year = {2016}, - url = {https://github.com/jodyphelan/TBProfiler}, -} - + 10.1186/s13073-019-0650-x