Mercurial > repos > jasonxu > matrixeqtl
diff MatrixEQTL/man/plot.MatrixEQTL.Rd @ 0:cd4c8e4a4b5b draft
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author | jasonxu |
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date | Fri, 12 Mar 2021 08:12:46 +0000 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/MatrixEQTL/man/plot.MatrixEQTL.Rd Fri Mar 12 08:12:46 2021 +0000 @@ -0,0 +1,112 @@ +\name{plot.MatrixEQTL} +\alias{plot.MatrixEQTL} +\title{Plot histogram or QQ-plot of all p-values +} +\description{ +This method plots a histogram or QQ-plot of p-values +for all tests performed by \code{\link{Matrix_eQTL_engine}}. +} +\usage{ +\method{plot}{MatrixEQTL}(x, cex = 0.5, pch = 19, xlim = NULL, ylim = NULL,...) +} +\arguments{ + \item{x}{ + An object returned by \code{\link{Matrix_eQTL_engine}}. + } + \item{cex}{ + A numerical value giving the amount by which plotting text and symbols should be magnified relative to the default. + } + \item{pch}{ + Plotting "character", i.e., symbol to use. See \code{\link[graphics]{points}}. + } + \item{xlim}{ + Set the range of the horisontal axis. + } + \item{ylim}{ + Set the range of the vertical axis. + } + \item{\dots}{ + further graphical parameters passed to \code{\link[graphics]{lines}} and \code{\link[graphics]{points}}. + } +} +\details{ + The plot type (histogram vs. QQ-plot) is determined by the \code{pvalue.hist} parameter in the call of \code{\link{Matrix_eQTL_engine}} function. +} +\value{ + The method does not return any value. +} +\references{ + The package website: \url{http://www.bios.unc.edu/research/genomic_software/Matrix_eQTL/} +} +\seealso{ + See \code{\link{Matrix_eQTL_engine}} for reference and sample code. +} +\note{ + The sample code below produces figures like these: + + Histogram: \figure{histogram.png} + + QQ-plot: \figure{QQplot.png} +} +\author{ + Andrey Shabalin \email{ashabalin@vcu.edu} +} +\examples{ +library(MatrixEQTL) + +# Number of samples +n = 100; + +# Number of variables +ngs = 2000; + +# Common signal in all variables +pop = 0.2*rnorm(n); + +# data matrices +snps.mat = matrix(rnorm(n*ngs), ncol = ngs) + pop; +gene.mat = matrix(rnorm(n*ngs), ncol = ngs) + pop + snps.mat*((1:ngs)/ngs)^9/2; + +# data objects for Matrix eQTL engine +snps1 = SlicedData$new( t( snps.mat ) ); +gene1 = SlicedData$new( t( gene.mat ) ); +cvrt1 = SlicedData$new( ); +rm(snps.mat, gene.mat) + +# Slice data in blocks of 500 variables +snps1$ResliceCombined(500); +gene1$ResliceCombined(500); + +# Produce no output files +filename = NULL; # tempfile() + +# Perform analysis recording information for a histogram +meh = Matrix_eQTL_engine( + snps = snps1, + gene = gene1, + cvrt = cvrt1, + output_file_name = filename, + pvOutputThreshold = 1e-100, + useModel = modelLINEAR, + errorCovariance = numeric(), + verbose = TRUE, + pvalue.hist = 100); + +plot(meh, col="grey") + +# Perform analysis recording information for a QQ-plot +meq = Matrix_eQTL_engine( + snps = snps1, + gene = gene1, + cvrt = cvrt1, + output_file_name = filename, + pvOutputThreshold = 1e-6, + useModel = modelLINEAR, + errorCovariance = numeric(), + verbose = TRUE, + pvalue.hist = "qqplot"); + +plot(meq) +} +\keyword{ QQ-plot } +\keyword{ histogram }