Mercurial > repos > jjkoehorst > sapp
diff sappDocker/crt.xml @ 31:957156367442 draft
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author | jjkoehorst |
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date | Wed, 29 Jun 2016 01:36:58 -0400 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/sappDocker/crt.xml Wed Jun 29 01:36:58 2016 -0400 @@ -0,0 +1,90 @@ +<tool id="DCRT" name="CRISPR detection" version="0.1"> + <description></description> + <requirements> + <container type="docker">jjkoehorst/sappdocker:CRT</container> + </requirements> + <command interpreter="docker">java -jar /crt/target/CRT-0.0.1-SNAPSHOT-jar-with-dependencies.jar + '-input' '$input' -output '$output' -format TURTLE + </command> + <inputs> + <param name="input" type="data" format="ttl" label="genome ttl file" /> + </inputs> + + <outputs> + <data format="ttl" name="output" label="CRISPR: ${input.name}" /> + </outputs> + <help> + CIRSPR prediction using CRT. Requires a converted + FASTA/EMBL/GenBank file. + </help> + <citations> + <citation type="bibtex"> + @article{Bland2007, + abstract = {BACKGROUND: + Clustered Regularly Interspaced Palindromic Repeats + (CRISPRs) are a + novel type of direct repeat found in a wide range of + bacteria and + archaea. CRISPRs are beginning to attract attention + because of their + proposed mechanism; that is, defending their hosts + against invading + extrachromosomal elements such as viruses. Existing + repeat detection + tools do a poor job of identifying CRISPRs due to + the presence of + unique spacer sequences separating the repeats. In + this study, a new + tool, CRT, is introduced that rapidly and + accurately identifies + CRISPRs in large DNA strings, such as genomes + and metagenomes. + RESULTS: CRT was compared to CRISPR detection tools, + Patscan and + Pilercr. In terms of correctness, CRT was shown to be + very reliable, + demonstrating significant improvements over Patscan + for measures + precision, recall and quality. When compared to Pilercr, + CRT showed + improved performance for recall and quality. In terms of + speed, CRT + proved to be a huge improvement over Patscan. Both CRT and + Pilercr + were comparable in speed, however CRT was faster for genomes + containing large numbers of repeats. CONCLUSION: In this paper a new + tool was introduced for the automatic detection of CRISPR elements. + This tool, CRT, showed some important improvements over current + techniques for CRISPR identification. CRT's approach to detecting + repetitive sequences is straightforward. It uses a simple sequential + scan of a DNA sequence and detects repeats directly without any major + conversion or preprocessing of the input. This leads to a program + that is easy to describe and understand; yet it is very accurate, + fast and memory efficient, being O(n) in space and O(nm/l) in time.}, + author = {Bland, Charles and Ramsey, Teresa L and Sabree, Fareedah + and Lowe, Micheal and Brown, Kyndall and Kyrpides, Nikos C and + Hugenholtz, Philip}, + doi = {10.1186/1471-2105-8-209}, + file = + {:Users/koeho006/Library/Application Support/Mendeley + Desktop/Downloaded/Bland et al. - 2007 - CRISPR recognition tool + (CRT) a tool for automatic detection of clustered regularly + interspaced palindromic repeat.pdf:pdf}, + isbn = {1471-2105 + (Electronic)$\backslash$n1471-2105 (Linking)}, + issn = {14712105}, + journal = {BMC bioinformatics}, + mendeley-groups = {VAPP Application + note}, + pages = {209}, + pmid = {17577412}, + title = {{CRISPR recognition + tool (CRT): a tool for automatic detection of + clustered regularly + interspaced palindromic repeats.}}, + volume = {8}, + year = {2007} + } + </citation> + </citations> +</tool>