view test-data/gbsx_demultiplex_data.R1.fastq @ 23:3b325560887b draft default tip

new version of gbsx: v1.2 with barcodeGenerator, demultiplex and digest
author koen
date Tue, 26 Jan 2016 07:56:34 -0500
parents 9819913262ec
children
line wrap: on
line source

@>chr21:9411295-9411494-0
ACCACTATGTCAGCTCGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCCTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCC
+
IA?FIA?G@BDEIC@<BIDABFI@EIEF?BGGEBAHEHCCGHC@IFFG@@DDD*HIBFHII?BFAD?ADHB@ACBEDCIB?E@DBBDBAEBGCDHDCH@C
@>chr21:9411295-9411494-1
ACCACTATGTCAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATTCCTAGGGAGATTTCTAGGTCCTCTGTTCC
+
@?B@CHIGHH?I@IIIEG?AIF@HHFEGDHGIHCICFDBHCDBI@CAIGHDE??EIIDBCIHI@CCCEBD<HDFG@E@?IEDHID@?D?BCAD@I?I@GD
@>chr21:9411295-9411494-2
ACCACTATGTCCGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCC
+
AE?A@B@@@AC#EHC?F@C?AHAHDEHEC?CBEBB@A?FDDGF??A@FDHC@DAAIA?CCBCBFHFFIDEHABDEC@GGD@BHAEEEB@@?EECHFFE?E
@>chr21:9411295-9411494-3
ACCACTATGTCTGCAGAAGGTGAGCAACTAAGAAGCTTAGCATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTTAGCAAAAGGATAGA
+
CAAIIGB?@DFFHCIFCBAIGAEDFACGFHFBBD@G?HAGHFAGDDAGEGGBHEFC?AC@GHAFDFF@DGEDACAABFEIAIEGI%DA?C@EI?@IHAIF
@>chr21:9411295-9411494-4
ACCACTGTGTCTGCAGAAGGTGAGCAACTAAGAAGCTTCGCATAAAATGGAGCTACCTGACTAAAGGGAAGTTAAGCAGACCTCTCAGCAAAAGNATAGA
+
?HBDFF>DEABAEBB@IEHEDCIDBDACHI@D?HBCGB&FBDCDIBHIHIIHEHHCDB?GGCGBA'E@HDE?CCGFCAH@CFIEDD?E@EEAF?"FCABI
@>chr21:9411295-9411494-5
ACCACTATGTCTGCAGAAGGTGAGCAACTAAGAAGCTTAGCATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAGA
+
IGA?@@A@GCGABAHG@FCECAGHIFGHCHBD?CBDIEFIGEFFGBCG@EFBAFCCHE@A?GICFCHE@GDEGEB???G@BBFG?CFDB@GCGEIAHBA?
@>chr21:9411295-9411494-0
CTCATACCACGCAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGATCCCAATGACTAGGGAGATTTCTAGGTCCTCTGTTC
+
GGGC@G@DEAGAGCBAHFCHABIBHEIGEHEG?AAGEH?HDDDBA@EIA?IC?FDE@BFEGB?&GGCHCCA?/FHGEDCFGCDBEADAFIGA@CHFEAF@
@>chr21:9411295-9411494-1
CTCATACCACGCAGCTGGTTAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTC
+
F?HC3EEFCIIB@ECGIFB"EHCG?CAHCIH?DI?EDIEIGGH?IDCBIIAFE@CIFGAHHHGH?IAGAA@D@BECEBGDCB@D?AHFH??EGA?IBDE@
@>chr21:9411295-9411494-2
NTGATACCGCGGAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAAGGCCNTGGGAGATTTCTTGCTCCTCTGTTC
+
+B.@ABBI-AC9IBG?HF@?GCEIGFDDEFCD@FHDFI@FDG?DEAIDD@DGIGIFIDFEGH?IGABIGF0IFG-7H@DCGFA?GIE*F>CIDACCGCCD
@>chr21:9411295-9411494-3
CTCATACCACGCTGCAGAAGGTGAGCAACTAAGAAGCTTAGTATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAG
+
EDHAA?ICGBEFIA?B@@GIEDGFEIGEDIAHB?EBDDDDEI@AEIBI@C@CFFCFIHCBII?GAE?C@ABADAHIBAFHDH??GGGEIHEG@I?D@FCA
@>chr21:9411295-9411494-4
CTCATACCACGCTGCAGAAGGTGAGCAACTAAGAAGCTTAGTATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAG
+
AIIFGAEAABIHDAE@HCE?CH@EE??A?DHFBAADFC?BGDDCFFDEIC?I?GAIAAI@AF@@ADEIEHICDEHGHDD@HADDEBCAEHIBEFE@A@BA
@>chr21:9411295-9411494-5
CTCATACCACGCTGCAGAAGGTGAGCAACTAAGAAGCTTAGTATAAAAGGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAG
+
CEBFD@CAIDEDGBFFGCB@?GBIDFDDGDEHADHF@FH?F?IIB@GC#?A?AI?BCHD@GDEBF?EG@A?C?D@EIHBA@DD@IHHCH@FDBIH?IHDE
@>chr21:9411295-9411494-0
GAAGGTCCTCAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCCT
+
GEIEDAAAC?HH@CBAHA@FAIEFEE@DEGGEFHDF?GA?IHHEED@ABGG?@EBEGGIHEFFGDIDGF?IBB@GDDAHIHCCEHFEH?EEEBFFHID?F
@>chr21:9411295-9411494-1
GAAGGTCCTCAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCCT
+
IGICFCADHGE@HICFIIBGB?IDCBHGBHG@A@H?@DEHDDEE@?EDEEFBGHDHGGDIA?GIA?D?HHBCH?GDBDHE@IE@C?BA@FFDGCCCF@HG
@>chr21:9411295-9411494-2
GAAGGTCCTCAGCTGCTGAATTTCTAGTTTGCCTTTTCAGCTTGGGATTAGCTTTTCAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCCT
+
BDGDFCBIBEG?CFG4GHIIEE@A@GD?F@HEI?D@GBI?E?,EIGIEAADG@BB?'@BBDABHDAIEADE?EIDFHIIE?B?AA?FGFIIGGF?FHHEE
@>chr21:9411295-9411494-3
GAAGGTCCTCTGCAGAAGGTGAGCAACTAAGAAGCTTAGTATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAGAC
+
BADC?IDAAGI@EGA@?CEEDIDF@GGE?B@BBIAIBEBDA@GIEGFGBIBE?DGI?EA?FGCDBCABDH?G?ADBEIBHAFE?AAHI@BACHDDGFEID
@>chr21:9411295-9411494-4
GAAGGTCCTCTGCAGAAGGTGAGCAACTAAGAAGCTTAGTATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAGAC
+
@H?@AAGBCIH?DCCC?IABE@?EH?BHFDD?BC@@BI?GEAFD??I@AEEEBECA@GI?FHHGF@CIHD?EGH?IHAHHFEH?@ADFEGIBICCBIDEA
@>chr21:9411295-9411494-5
GAAGGTCCTCTGCAGAAGGTGAGCCACTAAGAAGCTTAGTATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACNTCTCAGCAAAAGGATAGAC
+
I?GB?CH@IB?B?D@@@HID?HCH)EGEEGB@E?@EEBACEFICB@@I?EEIDF=BDFIGGBCBHDDFDIHCEEFGHBFI5AB?IAAIG?IDABHI?BDI
@>chr21:9411295-9411494-0
GCGGCGTACAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCCTT
+
AFI@H@GIEDD?CI?@GACH@E??@HDBDGIH@BBBCAICDBED@IHA?BBBDH?BHCF?GFCAFFFAEFEHFDAHGE@?E?IC?AC@FEFAHGCABDCA
@>chr21:9411295-9411494-1
GCGGCGTACAGCTGGTGAATTTCTAGTTTGCCTGTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCCTT
+
F@ACC@HAGIBFDEF?AGFFEAGBHDDF?D?AD(@??2DDF?GADHHCBFHBBH@HFHAGFCFH@CIADHEEAAAID?@BGB@AADIDBACICGG@??@H
@>chr21:9411295-9411494-2
GCGGCGTACAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTTCCTT
+
C?G@H@C@@CD?EA@AFAEFBGHIIAHCAIF@HCICDBDGA@GFC?G@E@G@DD@A??GBGDIHC?@DEEGEHG?BDIGHBIGBDA??B?EGEDCIBBCI
@>chr21:9411295-9411494-3
GCGGCGTACTGCAGAAGGTGAGCAACTAAGAAGCTTAGCATAAAATGGTGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAGACA
+
FH??FDFEIGBDHDDAHGD?BEHDDGHEEDDCD@GEGF?B?BIIDCIC$CIDE?FD??HGFBGDAIGHCGAICIHHC?HDIGCDII?HCIFHCCGBDCEE
@>chr21:9411295-9411494-4
GCCGCGTACTGCAGAAGGTGAACAANTAAGAAGCTTAGCATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAGACA
+
FB3GFDBFDA@EICD?AH@HE7DFA$CEFIG@@&FGADBBBIIG@DCCG@HE@?EGHIEIBI?GFIFAEGGGC?GADHCFB@BED?CCHBBEH@GFEGF@
@>chr21:9411295-9411494-5
GCGGCGTACTGCAGAAGGTGAGCAACTAAGAAGCTTAGCATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATAGACA
+
@@?HHEGICH?FEBF@?BFF?@GFGFAH?CEBGBBH?HHFGBEI@AAGHCGBDD@FBBHFGAH?EHBHA@FF@DGFBE@@EIFCHEIAA?@IIGEBC??A
@>chr21:9411295-9411494-0
TCAGACGGTAATCAGCTGGTGTATTTCTAGTTTGCCTTTTCACCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTT
+
B@FHCGAHGABAAAGHIBHBE.B@?F@FFECD@FCFHA?EDE)?CFCIFFECBD@EACC?FCDEB@DCIBBAGEDEEC?D?EBDDBCABEIHFA?F@@GC
@>chr21:9411295-9411494-1
TCAGACGGTAATCAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTAGCTTTTTAGGGGTCCCAATGCCTAGGGAGATTTCTAGGTCCTCTGTT
+
?G?@IHEHIDCGDIB?E@I@?EHIH?HIABEF@@IH@ACBHHIHDAFB@E@@GBBCIC@IEG@FBB?EADC@@HD@IFFHCFDICG@AE?BEFFEB?BG?
@>chr21:9411295-9411494-2
TCAGACGGTAATCAGCTGGTGAATTTCTAGTTTGCCTTTTCAGCTAGGGATTTGCTTTTTAGGNGTCCCAATGCGTAGGGAGATTTCTAGGTCCTCTGTT
+
?B@HCIDFIFADFIBHAGEA?GDACHHEGEFIE@DA@EA@FAGD@@CIGB?D9??CAEGIGIB7IB@BGAAIGG#CHEHICB??A?GCHCI@CCBAG@BA
@>chr21:9411295-9411494-3
TCAGACGGTAATCTGCAGAAGGTGAGCAACTAAGAAGCTTAGTATAAAATGGGGCTACCTGACTAAAAGGAAGTTNAGCAGACCTCTCAGCAAAAGGATG
+
CDEDFGIBA?G?FCHEGIFFBBE@?HCIEH?E?D?BAIF@@EBHH?AFICCI%IHBGFBIFFI?IDEEGGGEG@A,B@DB@EHAEHIDA@BG@C?IEBF2
@>chr21:9411295-9411494-4
TCAGACGGTAATCTGCAGAAGGTGAGCAACTAAGAAGCTTAGTATAAAATGNAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATA
+
A?ADCBFA?DGI?BGHECHAFG@I?CCCFAHG@HHHCIEI?FFIHBABCG?.CIBBEDGE??@?B@/EDGC?DAEEBBBHBBDFC@AFD@H?HC?GEIAD
@>chr21:9411295-9411494-5
TCAGACGGTAATCTGCAGAAGGTGAGCAACTAAGAANCTTAGTATAAAATGGAGCTACCTGACTAAAAGGAAGTTAAGCAGACCTCTCAGCAAAAGGATA
+
EEFDGG?D6GAAFFD@ACHFBGGDFAC@I?ACBIF@7FIIBIAAI@FB?@E?FBAIHDIIGFHFHEGDAEFFHH?HE?C@AGA@DBIAEIHH?GCG?A@@
@>chr21:9430880-9431000-0
ACCACTATGTCAGCCCACATGGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGGTTTCATATGAGTAAAAANCTAAGA
+
?I@ADIFCAHE?AA?DDBE@0DDCGC?EACCIFHEH@FACHFFH@BF@GFDEDIEBGB?AAAIIBBBABIFIBFBDH7FGHBGDICCCEC@EI7?CAEEE
@>chr21:9430880-9431000-1
TCCACTATGTCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATNAGACAAGGTATCATATGAGTAAAAACCTAAGA
+
8DBGFFIEFIDIGBEBIGAHHIHCEBB@DIB@BDCH?EAGEH@CFCEGDDE?EIH@IHBDBDED@F@#IDG@?@DACGEEFID@D@DHAIAFF@EAIBFB
@>chr21:9430880-9431000-2
ACCACTATGTCAGCCCACTTTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGGTATCATATGAGTAAAAACCTAAGA
+
AHHHCGH@CBBFHAIG??)@CGHC@@@?FHDHABG?GDD?@B@@BGF@@?GBAAGCHGABGCIBIBCGG?@IGBEABHFGAEDEHFD?CDB?FDEFDFFD
@>chr21:9430880-9431000-3
ACCACTATGTCTGCTCCAATGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAAGG
+
EECEDHDGHAAEBABFACCGDBEDHEAIIEFBIA@GF@GG@BD?FHHGBFBH@E?A??@GEADH@?C@IF?ICH@IEFFECC?I@II?F?BIGIDICFHD
@>chr21:9430880-9431000-4
ACCACTATGTCTGCTCCAATGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGCCTGATACTATCTTTACCTATCAAATAAAGG
+
F@C@DBEEEGBFDADIDABFBG@IBGCGBD@B?C?EEEGAD@IH?FEHFFFEBBBA?F@I?GFAGIF?D6CBDAEDAG@DAEBIG1FCICBIFDFFGGCI
@>chr21:9430880-9431000-5
ACCACTATGTCTGCTCCAATGTAAAATGATCACACACAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATCAAGG
+
IABDEDB@EAI?A@IEEBEBFA@HGG@DFCDFF@AE2AICC@@@H@CE@?IEIAHADDDCCHHDABDDI@@GH?BEDBDHFCHEBDEBED?BEHE>EACB
@>chr21:9430880-9431000-0
CTCATACCACGCAGCCTACTTTGACTAAGAAAATACTAAACCCTTTATTTGATAGAGAAAGATAGTATCAGACAAGGTATCACATGAGTAAAAACCTAAG
+
HH@@@DCEACGDEEID0BH+?HBGDBCAHIH@AAD@ABIAD@A@GGHIE@IDEBFH2F?@?EDDCDIDF@IIC@DCA'CHC?,DADDHC4F@FEEDBAFF
@>chr21:9430880-9431000-1
CTCATACCTCGCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGGTATCATATGAGTAAAAACCTAAG
+
GFIAG@?@!CB@GBCC?DBDIDG?FFF?E@??B@ACIACCCEBCCIHHBFFECD?C@?@HFDHDIEHHGEAC?GED?DEGHFBFBHFB?CFFB@IGCBFC
@>chr21:9430880-9431000-2
CTCATACCACGCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAAGTATCATATGAGTAAAAACCTAAG
+
EGIFF?E@FBDEFFA@?GI@HCF?CBGH?BIIABGAABCIAADDA@ABB@CGDIIGBECHEEHH?BF@IFGAHDC;@GH@HBF@FCFBGCGIFCAG?C@H
@>chr21:9430880-9431000-3
CTCATACCACGCTGCTCCAATGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAAG
+
GCBDC?IB@EEE@GD&@FBCCCHAHECIGCCIDEGEEEDCDABCAHHBHC@AC@CHACDFGEAGCBIGGDHHH@G@IEBCBGIHDFAICIFI@AEAACE@
@>chr21:9430880-9431000-4
CTCATACCACGCTGCTCCAACGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAAG
+
BEGBI@BCCIGCB@BDHFFED@BBFIFCFH@ECDFI@?IAC?@A?HHB@GBIBDE@FCCAGFAIB@HFAIEGFE@B@G@EE@F?AEEIHBFH?@I?@HHB
@>chr21:9430880-9431000-5
CTCATACCACGCTGCTCCAACGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATCCTATCTTTATCTATCAAATAAAG
+
FEBICC@AGHDDC@FBAEGED?EBAG@?IAD?GBD?IDAAD@BAHF?EC?ACFE?CF?I@ABABHAI@B@A?FCIB8@F??EHFBABGDDFCGFFHIBCD
@>chr21:9430880-9431000-0
GAAGGTCCTCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGTTATCATATGAGTAAAAACCTAAGAT
+
F?AF?CICGFD@@DH?@HEHDGDE@ADCB?GEI?HI?EHBF@AEDIDDI?CEIFEE@AIBA@EBICGBFCHBIH%@EBGA?CD@DBAGHAGHG@AGC@I-
@>chr21:9430880-9431000-1
GAAGGTCNTCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGGTATCATATGAGTAAAAACCCAAGAT
+
EFDFGHH6?DGCIG?IBDDAFG?HAGDGFICHGHADF@?FCFADIE?BB@DDAHDHEFGFCGEIC@@@BAGCIC@BD?AD*DFEFAFCDAEAIA!@IC?F
@>chr21:9430880-9431000-2
GAAGGTCCTCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGGTANCATATGAGTAAAAACCTAAGAT
+
EAADCFG?G@IFEID?AB@GI?G@DHAH/E@DCAH?CACGBAGEFB?CDID??HDFHFGCEIHDGGHCHAE@HCFIE.BH@FGG?DAIIAGHEBGBHGDE
@>chr21:9430880-9431000-3
GAAGGTCCTCTGCTCCAATGNAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAAGGG
+
BHBEHBI?BFC@IGDFCFA&"BHGHBG@E?AGIIA@H??HAI@IFI??FE@A?GCIAH?AFCHCBCCIBIBCBIDAG@GGCHI@DBDACA?DCD@CICGI
@>chr21:9430880-9431000-4
GAAGGTCCTCTGCTCCAATGAAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTANCTCTCAAATAAAGGG
+
?EE@AAFCHB@HFGBBFI@C+AIDHBGA@?E?BGDFB?DI?GEBDB?AE?ACC?FEBGDEI9DDGIAIFFG@AFB@HI?CAGGF0?@4EGHC@BAGAFDC
@>chr21:9430880-9431000-5
GAAGGTCCTCTGCGCCAATGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAAGGG
+
HH@??G@B?CGCD#FAID?IDGFDHEEEHFCGF?GEHAHIACEE@EFFBHCEGCIA?@EIGIHC@@DFCGFC@G@BHIBEFHD?HE?G@AC@BD?EE?EC
@>chr21:9430880-9431000-0
GCGGCGTACAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTTATAGATAAAGATAGTATCAGACAAGGTATCATATGAGTAAAAACCTAAGATT
+
FD@F@F@FCCBAF??FBGIGE@B?G@DGGH?H@?HC@FHHHF?H@?A:HB@ICD@IAEBCBFFCIIIBGBDABICDB?EFABE?HBABBG?GIBFB?IAG
@>chr21:9430880-9431000-1
GCGGCGTACAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGGTATCATATGAGTAAAAACCTAAGATT
+
DCHHC?B@@HG@C?FG?GGDICGAB@FCEEEF?IBDEHAFIGFBGHCCIADFIAEGAFACD@HF?AHDHB?FDFBB?@@CB?FGCHEH@H@EH?CGIHAF
@>chr21:9430880-9431000-2
GCGGTGTACAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAACGATAGTATTAGACAAGGTATCATATGAGTTAAAACCTAAGATT
+
@BH@3?EEDE?CIAA?HAG$HIEDD?GIAEEEBA???@AHAAAEFCFA?BAHAA@E>BHCFCIEA"BHGAEABHFDAGAAH?BCE?'EB?GA?FIEAEC@
@>chr21:9430880-9431000-3
GCGGCGTACTGCTCCAATGTAAAATGAACACACATAAATCTTAGGTTTTTATTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAAGGGT
+
AF?AIFBF@FCIHHIDFICIHACB?I@:?CE?@A@@@DGBE@CAGCIABBG=DF?ICEHI@E@C@FECIEB?I@DDAIC@@?CHH?@HC?FA@FIEEC@C
@>chr21:9430880-9431000-4
GCGGCGTACTGCTCCAACGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAAGGGG
+
G@AAEFBDIGI@F@@EC@ACDF?GB@E@DFG?HDCI?@ECACFDHB@D?AF@@@A@@GBDC?DB?BD?AI??EGGFD?FHDDGBCHGGD@H@AIEEA@H/
@>chr21:9430880-9431000-5
GCGGCGTACTGCTCCAACNTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATCATACCTTGTCTGATACTATCTTTATCTAGCAAATAAAGGGT
+
I?IDIBED?GCDEDIBBH*E@@HH@@BFH@?CHBHHIIB@?BCDGE?D?H@BHBAFF?&?H?G?CHAFDIDF?GEDCHAGDC@GFEE$@DBEDCAIEIGG
@>chr21:9430880-9431000-0
TCAGACGGTAATCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATGGTATCAGACAAGGTATCATATGAGTAAAAACCTAA
+
CGEBG??DEFD@EEDBCFBHGDAIBE@B???@CCAH@EAICEHH??DCCC7HCDAADH?IICGC:EGHICCH@@GDAEC@AC?CI@GDI?CGFHG@HGBB
@>chr21:9430880-9431000-1
TCAGACGGTAATCAGCCCACATTGACTAAGAAAATACTAAACCCTTTATTTGATAGATAAAGATAGTATCAGACAAGGTATCATATGAGTAAAAACCTAA
+
IF@?CBD?GGGIAACH?BEI?E@EFIIF?AGFD?@DICADCEACD@CEF?FAID@ICAGHHCF@AFA@FIAHBBDBIGAFBIGC?GDBGBFE@@GAEBBH
@>chr21:9430880-9431000-2
TCAGACGGTAATCAGCCCACATTGACTAAGAAAATACTAAACCCTTTANTTGATAGATAAAGATAGTATCAGACAAGGTATCATATGAGTAAAAACCTAA
+
AHF?E?G@AD@@FDIC?GBEGFGBADEDEEAAA?H@ICD?I@BCBDC@7BGEIAEHC?EB@CEFCEG@IDGICBF??BCBFCBD@GI?BGAAH@GAEBIE
@>chr21:9430880-9431000-3
TCAGACGGTAGTCTGCTCCAATGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGGTTCCTTGTCTGATACTATCTTTATCTATCAAATAAA
+
FGBGGH@?IC)CCFEHE?@I(CA@?AE@I?HGCGEDDIBEEDBGIDGE?@@I?ABDD?F?GBE>@:GBH?DIGDDAD?FAFDAEIFDFFFBFEHDEDHF?
@>chr21:9430880-9431000-4
TCAGACGGTAATCTGCTCCAAAGTAAAATGATCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTATCTATCAAATAAA
+
?EACHBHACE?GIHF???EGD&BGAIHCCFCBEDHCHIC@ICCHHEGCEI?H@CDBHFAEEC@DCHDD?AGG?AH?AFHDHGAE?DEA??AFBFH@GF?C
@>chr21:9430880-9431000-5
TCAGACGGTAATCTGTTCGAATGTAAAATGTTCACACATAAATCTTAGGTTTTTACTCATATGATACCTTGTCTGATACTATCTTTTTCTATCAAATAAA
+
AAHBBFI?ADHAIA?'@?7HBD?GACI@?F.GGGEADAEG?EC@DDHHDBDADCDIGBECIGIE?BCFBEI?FACI?B?E?H??AI'FICGDBD??BDD?
@>chr21:9431204-9431260-0
ACCACTATGTGTGCAATCCTAATTCNAGATCTAGCTTCAAGTCTGGGTCACTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
GDEFB?F??I2#IABFEGGHFIBBC.IIAEGFG,AAFC@?IFH@@FBEAB@D?@CIHBFFDAIA?DBDHEHH?BF?BHDH?BCADHB@FHHHHIC?AHE@
@>chr21:9431204-9431260-1
ACCACTAGGTCAGCAATCCTAATTCCAGATCTACCTTCAAGTCTGGGTCACTGTTCTCAACTGCTGAGATCGGAAGAGCGAGAAAAAAAAAAAAAAAAAA
+
BDD@HEG>?DCC??@CAFGCH@@?FDGAGFBII+FD@@HICHH5*BEDABFHGD?FGIIF,HD@DGF@B?IEDDIEAAFI?(GDHEG@A?@IIBGDBHF?
@>chr21:9431204-9431260-2
ACCACTATGTCAGCAATCCTAATTCCAGATCTACATTCAAGTCTGGGTCACTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
GA?FIAG?EHIDIDGBFHDDGAFIGAEHBHEIGB%DDFF?DDHIECBAIFCB?IHEEGACH?DGAB@IF?EHD@?G@?IECBFFHDEDHECFCIAHHEG@
@>chr21:9431204-9431260-3
ACCACTATGTCAGCATTTGAGAACAGTGACCCAGACTTGAAGGTAGANCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
E@@C@HHIAB?AFAI@@FH?CFFEB@ICEBHGECGGGAI?IIHDEBA$I?@@FBDBAHIABAC@EGHF@CD?DGHDDEHDFEEFHIH?GG@@GFEFCG?D
@>chr21:9431204-9431260-4
ACCACTATGTCAGCAATTGAGAGTAGTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAGAAAAAAAAAAAA
+
BAH)BBEHFFACAFH-BF?@IB82BDBBDD@HG?AI?A?HBIG?EGI?ABHFFC?@E?E?B@GFAF@FHFIA?@GBAIC?DG@CFD?$E?EIHBFCBHFI
@>chr21:9431204-9431260-5
ACCACTATGTCAGCATGTGAGAACAGTGACCCAGACTTGAAGGTAGATCTNGAATTAGGATTGCTNAGATCGGAAGAGCGAAGAAAAAAAAAAAAAAAAA
+
F?GIEFCAGAIAA@@@/I@IBIGGBDCAC?GIFB@AEG??GGDIGFDCID&BIIACHCB?BBA?E0CB@GBEAEGG?ABFC?3?FEABH@D@HBCFEAHD
@>chr21:9431204-9431260-0
CTCATACCACGCAGCAATCCTAATTCCAGATCTACCTTCAAGTCTGGGTCACTGTTCTCAAATGCTGAGATCGAAAGAGCGAAAAAAAAAAAAAAAAAAA
+
A??@IHACEAEICGFBDGID@EBGEDDEGFGICFCHFH@FE@IIC?I?D@?EAC?HEA?AGFIIE@AIIFCEA8CDBDCI?DCGCHB@CHAAGCA?GFGH
@>chr21:9431204-9431260-1
CTCATACCANGCAGCAATCCTAATTCCAGATCTACCGTCAAGTCTGGGTCACTGNTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
?EHD@D@?B.ECFAG?GEFGFDDC?E?@FDG@?@@A"EAA?CC?GDDCHAAGIE%@@AIAECE$CEFHCECEGFB?AHGEGFAG@E@BF@ICIEDHAGBD
@>chr21:9431204-9431260-2
CTCCTACCACGCAGCAATCCTAATTCCAGATCTACCTTCAAGTCTGGGTCACTGTTCTCAAATGCTGAGATCTGAAGAACGAAAAAAAAAAAAAAAAAAA
+
IBA%DHBHHBFCDGCBG?D?HBEDGCIEHFCE?HGECBDA@FECHDFIECF@EBBCIGH?F@G?GHCG?E@I%I@?B8+EGDDIBIDAEAC@IFIGGFBH
@>chr21:9431204-9431260-3
CTCATACCACGCAGCATTTGAGAACAGTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
HAGHCD@BEFHAGI?@E?CABC@@HHC@AHDFACBGIFAHI???GFB@A@DBEF??AGDBCFI@@AFCAA?II?HI?IHCI?>CGFFEI??BD@CCIDAH
@>chr21:9431204-9431260-4
TTCATACCACGCAGCATTTGAGAACAGTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
2IAIA@FC@BBC@CDB@EDDECG@?EAGCEFH@IHBAIBCAD@@AEAH@HHHD?AG@AI?EF?GIB?AICHFBGFDGBB?@FIGGBFEGCFA?HAIEIHA
@>chr21:9431204-9431260-5
CTCATACCACGCAGCATTTGAGAACAGTGACCCAGACTTNAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
FCFGBGD?AID@@?HFDFA@DGHBCHBB1EACD?FGH@G9FC@CB?DGAECIFC@IGGCDCCB@CGICB?AICBGCEEBBI?BFICGG@EG?EDDEI?FE
@>chr21:9431204-9431260-0
GAAGGTCCTCAGCAATCCTAATACCAGATCTACCTTCAAGTCTGGGTCACTGTTCTCAAATGCTGAGATCGGAAGAGCGTAAAAAAAAAAAAAAAAAAAA
+
EEGC?AEDFDAAIB?I?CCIDI4BIDBII@FGCGECEFIEHC?G,BBBIG?BGF??ECGD@EAB@EFB?FCE@E?IAF@(EIBCBHGA@FIGDEDB@C?H
@>chr21:9431204-9431260-1
GAAGGTCCTCAGCAATCCTAATTCCAGATCTACCTTCAAGTCTTGGTCAGTGTTCTCAAATGGTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
CA?A?IFCH@DBEHED?HEH@H?EIHCACBICEHHACF@IHIE3HIF@EIFA@FECHBCCAB0HA?BFDI?DBDFHH?IHC@ECHEG?F?B?@AEGDDBA
@>chr21:9431204-9431260-2
GAAGGTCCTCAGCAATCCTAATTCCAGATCTACCTTCAAGTCTGGGTCAGTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
FADCDGHIABGBCAGDD?DEIE@FHA?ADGBIEDDAABCI@H@DC?G?@GDADCEBFGIBCADGEBG??AG@CE@?CDCGFIBFDDI@CFCAGGGEHGA@
@>chr21:9431204-9431260-3
GAAGGTCCTCAGCATTTGAGAACACTGACCCAGANTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
CCC?HEBHB@?FGEA@DBB?ICDC@?BH?E@EEE.GEIGGGHGGFEABCIDB@?DAIIDDBB@BCCHFDIFCEBAGGBFI?@FAGHIFCF?FAC?CHIC@
@>chr21:9431204-9431260-4
GAAGGTCCTCAGCATTTGAGAACAGTGACCCAGACTTGAAGGTGGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAACA
+
EHHECCEE@CBA?BBCB?DAD?DH@G@??F@IA?DADEI@ABE.FDAFDHEFHH?@GFF@E?E?GFAAI@EH?HFC?AGB?IEIGG@@H?@A@I@?EE$H
@>chr21:9431204-9431260-5
GAAGGTCCTCAGCATTTGAGAACAGTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGTTCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
CCBGIFGD?FBHABHGHGH?F@@FDDAF?EFFACBB?AHEIBBAE@@FAFEDBIBBDICBGHCFDBF2GB?DIC@@EHAFA?FFIIICBABBDCA??HDB
@>chr21:9431204-9431260-0
GCGGCGTACAGCAATCCTAATTCCAGATCTACCTTCAAGTCTGGGTCAGTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
@CEHHF@@G?EHIBDFEC@DC??E?ID@E?C@?AFDACD@BEGHBC@A??GBB?ADEGGIHEGB??DD?DIAFBABBB?ADGGFEI@GCDHGI@?CIFHG
@>chr21:9431204-9431260-1
GCGGCGTACAGCAATCCTAGTTCCAAATCGACCTTCAAGTCTGGGTGAGTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
?D?GIHAHBDHDBECCD@G,HBCA@*@HB8CG?A@?HE@GCDBB@C;IGC@@?IIBBCEF?GFAE?HGAFBE@@H?FAAHCEIAEFCEIDDHDE@BF@FG
@>chr21:9431204-9431260-2
GCGGCGTACAGCAATCCTAATTCCAGATCTATCTTCAAGTCTGGGTCAGTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
IGHGE?BBDFH@IIBIBHHI??A@H@CHFG@8C?AHAFAD@A@?FDBFDEG@BDAAFEC@GEFFFF?GB?BDAAC?@ECBGFGBHDBFEDIHEBCIFE?H
@>chr21:9431204-9431260-3
GCGNCGTACAGCATTTGAGCACACTGAACCATACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
ABF+FFBDAEHIHFEACCF!@GDIDHG.I?G"HGDGI??EDICH?CI?FFDHDGHCHE?FGACDHIADICC@DGEBF?AEGAEF@DHAGI@IFBFBFCAH
@>chr21:9431204-9431260-4
GCGGCGTACAGCATTTGAGAACACTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
??@BFBGIC??C?FFD@A?GF@DF?AGFIIFEIBHD?GBAECF?I@?@??D@CEGIHHABHDBBC?BEBEI?ACCHBBEIEHFHADA@EDDH?HC?HHFH
@>chr21:9431204-9431260-5
GCGGCGTACAGCATTTGAGAACACTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
DB@GCBD?EEDGA@CHE@?CDFAGCDH?EBBBIEH?AD?HCCGAHAIGFB@HFAFHHIFFADBHB?CFH?EA?C@BDA@A?H?I?EI@CBFBAG@A@EEB
@>chr21:9431204-9431260-0
TCAGACGGTAATCAGCAATCCTAATTCCAGATCTACCTTCAAGTCTGGGTCACTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
CDG?IEDACAGAGGAI@HBIGGGHCFBC@?EH?CHBECDA?CGD@ACBEAF?EEEFEHFDIHAF?CD@GIIF?I@DG@DABIEGFEHF@GFH@C?CB?IG
@>chr21:9431204-9431260-1
TCAGACGGTAATCAGCAATCCTAATCCCAGATCTACCTTCAAGTCTGGGTCAGTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
A@H@H?CHIC@D@CBIFB?EB@E?E:FDICEFIIGGH?AEAIA?CHFEHIADDBCCDFCCAF?EFFBAGGIH@FFFI?AE@CBHCGAAEA?H?HA@?C@@
@>chr21:9431204-9431260-2
TCAGACGGTAATCAGCAATCCTGAATCCAGATCTACCTTCAAGTCTGGGTCAGTGTTCTCAAATGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
CB?CAEE@BF?ACDE?I?FCIE3D;GDA@?BHE?DEFA?H?AI@IC@@IGDGBA@CAIEHGEBI@AIC@@I@HI?EGCDH?EIFDID??AA?IFA?CGHB
@>chr21:9431204-9431260-3
TCAGACGGTAATCAGCATTTGAGTACACTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGGGAAAAAAAAAAAAAAAAAA
+
C@F?EIFFEHAG@I@?DEF?EFI6HH@HIBED@;?FCEBADHDCD?C@AAEC??@H@DBFEGGGAED@FDFEHEFDEGBC6CGGCFIDBGHHGBBHCG@@
@>chr21:9431204-9431260-4
TCAGACGGTAATCAGCATTTGAGAACAGTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAANAAAA
+
BCCCAABAFFDDHCGHB?G?AECF?A?DGCC?@?GH@?H?B?GHDH?@HEH@DBAAIHE?DEIBF?EFBAACA@ID?FIAFG@IACFEGADAIHC"AEIB
@>chr21:9431204-9431260-5
TCAGACGGTAATCAGCATTTGAGAACAGTGACCCAGACTTGAAGGTAGATCTGGAATTAGGATTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAGAAAA
+
@?IFDICHI@FEACBIADGB?GAAEEBBBGC?EDCBA@IH??DFCA?IBG??@?FHEDFCHC?@I???CIIACEACD@?F?HCGB?DH@?G@IDD'@EDH
@>chr21:9431992-9432055-0
ACCACTATGTCAGCCATGGGCGGGCCCAGGAAAACGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
@@ACA@@BI@HDEHCBB?DEGAEG?DB@EFDA?C3EA?BBCFH?CGCIHA@@ICAIC@AGHHDIEIIDA@CEAFCFGI?BB?E?EDDE@FAEHGBEIC?E
@>chr21:9431992-9432055-1
ACCACTATGTCAGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCACTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
A?H?GBC?DCHDEHCF?BD@B@I?EECE@CC?IFEBAECDH@@E?FCD?GIFHHAI=F@IGBBBIA@A@FBEBG?@C?I?FG@EH?@DGHE?FGEBABCF
@>chr21:9431992-9432055-2
ACCACTATGTCAGCCATGGGCGGCCCCAGGAAAAAGAACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
GGB@B?EAEEIFDGGCCHGFCG@-IB@BDBAI?EFH&EHE?F@HIHIIIHCAIDFGHHI?DB@AC@FIG?CD?A?CB@AEG?EBFFGGH@BADFHDC?GD
@>chr21:9431992-9432055-3
ACCACTATGTCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
IDADGGHGGHFG??GGCICEHEGHGDBFH@FCCGDCGDHD?@DHBHBABE?IF@DGBACAHDEHAFE@GHB@H?GC@BHGE?EAD@HE?@DAFI@CHFB?
@>chr21:9431992-9432055-4
ACCACTATGTCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCGTGGGCCCGCNCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
FBICICBGEGABFGABB?AHDGHEFAH@CIFCADDFIGIGHHGHBDHBFDI@BA*AHDI??IH@:GD@CCB@BDEII??IBDGGHIEBCCHGGBFBBIDB
@>chr21:9431992-9432055-5
ACCACTATGTCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
HEHACGGCH@I?ED@@@G@IEGGD@DIDHCFADFD@BCICC?FIGGGBCAAIEEBC@IDIECA?FGDAFDGEBAGDG?HHAHHC?@H?CFH?DFFFCBAC
@>chr21:9431992-9432055-0
CTCATACCACGCAGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCATAGATCGGAAGAGCGAAAAAAAAAAAA
+
FID?DBEDECDGCFF@ABEB@?IA@IEDGGGBBHH?DCEEE@F?DCDIC@DDHIDHBE@CFBGDE?CF@D@AB)EDDADBHFICGFC?GACGBIE@@FFD
@>chr21:9431992-9432055-1
CTCATACCACGCAGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
EID9@ICHD@FE?HIF?HFDCHAA?FB@A??IHHGE@AI@G??HDCCGIG?EGDC?CI@F@CIGDBEABGBGGBCAFBFBHB@IFDHCH@DGBBIEHEBG
@>chr21:9431992-9432055-2
CTCATACCACGCAGCCATGGGCGGGCCCAGGAACAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAACAAA
+
??AECGHGI?DA@CEFIIHBIEIEFFGECCGDB'FAAA@BAHI?E?GIHIACDCCGAII?HH@%GEGBFAHCAI?AEHGED??GBBCD?E?ICI@@6FFG
@>chr21:9431992-9432055-3
CTCATACCACGCTGCCAGTCGTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
CBGFFGCCGE?DD?HBH@GC0@??HA?F?D@@FA@HCACBHI??HFADGHAIBCFIFCEFIG@I@?@@IADHBBBHEIGAB?A?GDBACFI@CECIHEGG
@>chr21:9431992-9432055-4
CTCATACCACGCTGCCNGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
CHAIC@FBHHDD@?CF=@FHCBFFGG@EIF?BEBHGFCBB?B?BACCIE@IB?I@GIDHCD@G?@HBDCAEC?D?BB@@I@GAEGGDF@HBAHBIIECC@
@>chr21:9431992-9432055-5
CTCATACCACGCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCAATTGCTGAGATCGGATGAGCGAAAAAAAAAAAA
+
H@AB?BD?HG?IE@DBFADEGD??AAFGCFAACBHADAC?BDGABECFCHAEFA?GGIE@F?DAGF4HA4?HBGA@F?A@IA/FEEGCAFDGFDAGA?HH
@>chr21:9431992-9432055-0
GAAGGTCCTCAGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
??H@GD@DF?AGCAIC@FB@GFI@??FCDE1CBIIGH?FCDH@@HC?FADEI@AI@?EBFHCAEEDD@CHB?IBI@DI@FBAEADGBGHAIII?EI@F@@
@>chr21:9431992-9432055-1
GAAGGTCCTCAGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
IECCB@DFECBDIIB@AEFBHHDH@GCEC@A?CC?C@CGB?B@CEIBHHC?FEIEAIB?E@B@BBHDF?E?E?D@IGE?HEHEAEHGEC@?B?F?E?EAB
@>chr21:9431992-9432055-2
GAAGGTCCTCAGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
ECDAHICDAAIAI@FFBDFAG?HIE@AICGH@@G@G?CAABEE?GHFABGD?FB?DEBIGBCH@EIADFEEHG@GDEGBD@FFFC?@HEDF?D@GBIEAC
@>chr21:9431992-9432055-3
GAAGGTCCTCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
I@DAGG@HFC@@IBFE@BFFEEDGCD@BDACD?FIIAABDDDE@EGCDBEBDEBGIH@AGEFE@CEEA?ICD@GAEFE??HAB@DA@EE@E@FCIA@DAG
@>chr21:9431992-9432055-4
GAAGGTCCTCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCATGGGCCCGCCCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
BGIEDGFFFAEEIHFGE?IACBFH@CAA?AFIHD?FDFDHICECAHCEG?HHB,IFDAH?BGGGAADD?HEIDAIGGAA@DD@CCAEEE@IHACFCHGFE
@>chr21:9431992-9432055-5
GAAGGTCCTCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCNGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
CE@??CHCHEIC@IFFAICD?GD?AC@DHHF@C?HCGFBA@FH@@@HAAHEDIADC@GAHH?HFHAGCIE.EBCFGII?@@ADBAECBIE@IHCE@ADD@
@>chr21:9431992-9432055-0
GCGGCGTACGGCCATGCGCGGACCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGAGAAAAAAAAAAAAAAA
+
@DDHFHFFI?E?@GD?)FFFF$?HIIBBCBA?H?IGB?GHA@?GFGDGD@BHHI?F?CEIBA@FIGICDB?CD?HFC?BIAHG'DEECDAFCBC@?ICFA
@>chr21:9431992-9432055-1
GCGGCGTTCAGCGATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGGCTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
HHHEDCH&EDBC:AHEEADGGBG?IA@EFGCCDAEFB@AICFFGB?EC@DDCHBDABA@CCGI%DEACHDHH@CBBGGCHCCGHG?C@CFCE?@BBB?DG
@>chr21:9431992-9432055-2
GCGGCGTACAGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCNGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
FHCB?HICIA@AABCDCGDHGE?GA?CAAECIFIIIDHCGBAEAAAFECH@IBCAEE(I?BF?GDFEEDG?F?EIBDIBE?FAD??F@@BDHGGHHEIBH
@>chr21:9431992-9432055-3
GCGGCGTGCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
GDCFH@@9BAE?@IGIFIH@IDI@HCCI?BHDI?FHG??EDDIHID@H@IBE?B@@HI?FE?AFG?FH@GFHDH?ACEC@AFE?DA@I@ADG@EIGIDF?
@>chr21:9431992-9432055-4
GCGGCGTACTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCCGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
?CGAEACHAAIBG@GB@DH4HFDF@EA?BIBHIGA?CB@??@HFAHDBA@@C%AGGED@CG@C@@EH?BIEBC@FDF@B@@DHIC@ABHIGD@A?DADEA
@>chr21:9431992-9432055-5
GCGGCGTACTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCCGGGCCCGCCCATGGCCGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
?HBIDIEFFF?C@HFDGCDAA?HFE?C?G@AICABDCHDCG?HH@IC?F@?AI1IB@DDDG@EE?AHFCBFHHAH?BH@HICFBEGHEH@I@GH?@A?HF
@>chr21:9431992-9432055-0
TCAGACGGTAATNGGCCATGGGCGGGCCCAGGAAAAAGCACCATGAGTTTTGCCTCCAGTCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
CBHIA@IC@BID>IC@FD?D@CEEEFIFFCCIII?@IBDHIHEEHFI?FDD?F@BGBAGCACC?BCI@?CFCHE@?HFFFCICCCBDIDG?EBAFFB?DD
@>chr21:9431992-9432055-1
TCAGACGGTAATCGGCCATGGGCGGGCCCAGGNAAAAGCAACATGAGTTTTGCCTCCAGGCTGCAGGACTGGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
??DEDGEHE@?IBHEA@?E@EHFE?GIEE@CG7IA@BFBB/HB@@CABHDAD@HAACHI9@GHDIEBG??IFBECGD@AE@FAHEEGE?IH??AAGDH@C
@>chr21:9431992-9432055-2
TCAGACGGTAATCGGCCATGGGCGGGCCCAGGACAAAGCACCATGAGTTTTGCGTCCAGTCTGCAGGACTGGCAGAGATCGGATGAGCGAAAAAAAAAAA
+
AFECHH<GHEACFD?FEFCDD??B?CHGGI@@B.I@@CFCDHHBB@BI@HAGB,HBCAB?AFIDA@HIADHHAFDFDEI??HC2IGHDCGDHE@?DCA@I
@>chr21:9431992-9432055-3
TCAGACGGTAATCTGCCAGTCCTGCAGACTGGAGGCAAAACTCAAGGTGCTTTTTCCTGGGCCCGCCCATGGCCGAGATCGGAAGAGCGAAAAAAAAAAA
+
CH?CGAGGDGGI@FEIH?@CFDHBG@IFGC?I@FGHCH@IDGCI/E?IBDBGC@FE?CDEEDFBDDGBEFEHDAFE?BAEFCIF@DIG@DD@EHA@@@I@
@>chr21:9431992-9432055-4
TCAGACGGTAATCTGCCAGTCCTGCAGACTGGAGGCAAATCTCATGGTGCTTTTTCCTGGGCCCGCCCATGGCCGAGATCGGAAGAGCGAAAAAAAAAAA
+
EABIFDIGHDI@DDA?BBG?C@@CFAF@E?EFHH@??BC#BF?IAD@HDGEAGDF@BABEEHC?GG?DFABFFIAAHBF?H@?IAECFB@AACDHBEEDI
@>chr21:9431992-9432055-5
TCAGACGGTAATCTGCCAGTCCTGCAGACTGGAGGCAAAACTCATGGTGCTTTTTCCTGGTCCCGCCCATGGCCGAGATCGGAAGAGCGAAAAAAAAAAA
+
HG@IC@@CFFCB@GIIADD?HADHB??F??ABIGC?DDDC?BEB?CDC@B??B?DEDIAC!FH?IGICGFDB?BAF@GHBFFFFDDDAAEADGBGFC@?A
@>chr21:9432052-9432146-0
ACCACTATGTCAGCCTAGCCTGCAGGTGGGGCTTCACTGGGGACCAATCACCTTCCACCCAGGAGCCTGTCTGCCTCGCACAACCATCCATGGCACCCAG
+
IHEBBBAFEHD@@?DC@DFIFBGI?EAH@EAAE@CGECC?AB?HH>GGGHA@A?AFBACD@E??EAE?HBEDGIHCF!CCGFIHEAC??HC@C@C@GF@?
@>chr21:9432052-9432146-1
ACCACTATGTCAGCCTAGCCTGCAGGTGGGGCTTCACTGGGGACCCAGCACCTTCCACCCAGGAGCCGGTCTGCCTCCCACAACCATCCATGGCACCCAG
+
HAFEI?GFAA?BH??IEC@CIFCDIIEIDBCI@DDIGGAA@G@FDAD=DA?BFFC?GDHB?D?@?I@6@?AACDHDIE@HEFDDHIGIGACF?FD8FB@>
@>chr21:9432052-9432146-2
ACCACTATGTCAGCCTAGCCTGCAGGTGGGGCTTGACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCCAG
+
CE@F?@AF@AHADHBICEEIFHC@BAH?BFDEDG0?DDFHFIIBEDGGAC?AHBAI??FDICGDHEGAHAFHA@B@IE@CHHIFCEHBCBGCIH?FCEBE
@>chr21:9432052-9432146-3
ACCACTATGTCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGTAAGGTGATGGGTCCCCAGTGAAGCCCGACCTGCAGGCTAG
+
DHBDBIGCEECEHDHBIFDGGFH?AGBIEAFDGHCEA?IAIGDHEHDBBA?BD?IBFH?3DBICGGFGDH@HGGADEHFA,D?HF@6GEGGFAFAFFG?A
@>chr21:9432052-9432146-4
ACCACTATGTCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGCCCCANCTGCAGGCTAG
+
9CABFIGADCF?@@AHIH??GDIA0DHDAIFCB?ICIBE@E@BD?BICE?@HBA@BGAB@FDAD??GADCACGBIF?GEBGIHFBDAE7DABFFCCHIAH
@>chr21:9432052-9432146-5
ACCACTATGTCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGGGANGGGTCCCCAGTGAAGCCCCACCTGCAGCGTAG
+
?GBIEEBHBHACI?I?HHD@EDIECBHABE?C@HGIIDBDBDDEE4GB?HEEHF?AIHCHBGHH=EG(CFA?GCBBHAFHAIACEFAG?DCFFA?72?CF
@>chr21:9432052-9432146-0
CTCATACCACGCAGCCTAGCATGCAGGTGGGCCTTCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCCA
+
GAAGEHICGDEBHIAGIH@F&AG@?@HDAAC?E@IIADHEDIFHFAE@DG?GGAAB@GHH?ACHACDFC@ID?GCCAEB@GBI?GDIECIG?@B@@HBDG
@>chr21:9432052-9432146-1
CTCATACCACGCAGCCTAGCCTGCAGGTGGGCCTTCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCAACCATGGCACCCA
+
?EHIGHAAAC@FFDDI?DIEC@AADDE@HHAGIGE?@?A=C?BIHHCDFGBHHGBHICE@EAHIFHD@@FAF@DHBBBHHDE@@BFE<CBC?B?GBGBFE
@>chr21:9432052-9432146-2
CTCATACCACGCAGCCTAGCCTGCAGGTGGGCCTTCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCCGCCTCCCACAACCATCCATGGCACCCA
+
CDC@@C?B?FIGBEBBGCAA@IGH??IDGA??CD@GCAEF?BDBEH?DBGBGIC.BDAAAFIHGDBFGDDBG;CI@GECC@?EFC@?IDDHFE?EH?CD@
@>chr21:9432052-9432146-3
CTCATACCACGCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGGAGGTGATGGGTCCCCAGTGAAGGCCCACCTGCAGGCTA
+
IGHD@FDHDI@@B?CFD@EDBIFGA@ECICEBCHCHAHAADF?@I?A@EA?'B?BD@AGHE:IEDFAC@G@CCHHEDIA?I@@AGIH@CCC@FAI@@@F@
@>chr21:9432052-9432146-4
CTCATACCACGCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGGCCCACCTGCAGGCTA
+
ABA?IGECGBFDAGGA@FC@CEICI?@EID?C?IACFGC@DGCFGFHBBGIG@BD@HHBBGDCAB@IBCF?E@FECGH@F?AECIEIGDEDHHHEI@CAG
@>chr21:9432052-9432146-5
CTCATACCACGCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAACGCCCACCTGCAGGCTA
+
@BGGHHDDGHDFFGBBEGAD?@EAHF??@@F??@?FII@ADFBB@IECAHI?B@?C@HFAHGAAD?IFACIFABICEHEIBGA)DDAECFEGDDFBEB@G
@>chr21:9432052-9432146-0
GAAGGTCCTCAGCCTAGCCTGCAGGTGGGCCTTCACTGGCGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCATAACCATCCATGGNACCCAGG
+
AAGCGA@CI@EIB?B?CAF?IBDDHIDCCBGAEBHIE@E/H?HGFIG@HDG?B@HIEGCEIIHB?DIBE?I?AG?@AGI/CDIIB??FFDCI%FH@FBH?
@>chr21:9432052-9432146-1
GAAGGTCCTCAGCCTAGCCTGCAGGTGGGGCTTCACTGGGGACCCATCACCTTCCACCAAGGAGCCTGTCTGCCTCCCACAACCATCCATGNCACCCAGG
+
@?ADA?ABCHF@HDIF@DHFED?@BGHEBGGDIGI?AC?CDEA@GCACFIICFDFGHC-EAAA?FCFHH?DCIAHHI?E?EA@ACHBCICH1DCICHII@
@>chr21:9432052-9432146-2
GAAGGTCCTCAGCCTAGCCTGCAGGTGTGGCTTCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACTACCATCCATGGCACCCAGG
+
CIEDIIG@??@?CGHI@FFB@CABC@E9G?FDI?IFCCBECA?BGH?GICICECCHIHGFHEGIAI@@?DCDGIAEEHC?*?AC??G??CB@HHHH@BFI
@>chr21:9432052-9432146-3
GAAGGTCCTCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACNGGATCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGCCCCACCTGCAGGCTAGG
+
HCHEIIE?HC@@BABGADAGCIH@HAD??FECF@EHA@EIDDDAD=EI8G?CBCDGGHEDABDEH?EFG?EFHGE@I@DGFDCIIGB?FHFIA?IED@F?
@>chr21:9432052-9432146-4
GAAGGTCCTCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGGCCCACCTGCAGGCTAGG
+
CEI?EFBI??EHIAHFGAAFDBCAEGBDIF?HC3IGHBFC@ADDDBH?C@A@ECDC?ED@AF@ID?E*FCB@EHFHAGDBIBBGG?EECA@FA@?HADB@
@>chr21:9432052-9432146-5
GAAGGTCCTCAGCCTGGGTGCCATNGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGGCCCACCTGCAGGTTAGT
+
BDFBF??FIGCECACBE??@?IFH4@FCCFCFEBC@CFHGAF?EIE@??GDGEIBFGHAAIIAG?IEID@D?HE@GADDBFAFCG@@DEBGAAEE#BAF;
@>chr21:9432052-9432146-0
GCGGCGTACAGCCTAGCCTGCAGGTGGGGCTTAACTGGGGANCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCCAGGC
+
@ABGFHCIBIGGAEIAHEI@BEGCADECFFAF:IFGII@FG=GEB?EBGEECGDBIBFCFGIA@CI?IIBDIHFGDFBB@AG@H@@@BBHEIC@IE?H@A
@>chr21:9432052-9432146-1
GCTGCGTACAGCCTAGCCTGCAGGTGGGGCTTCACTGGGGACCCATGACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCCAGGC
+
F@"BH?HIHIAF@?FDBDC?GGHIF?AH?HHE@EAFDDG@GFC?EH,EIC@DF?C@AAGDFHAFA?AAFG??BBE@@CBAI@HFFD@GCGIB?CIDFIIE
@>chr21:9432052-9432146-2
GCGGCGTACAGCCTAGCCTGCAGGTGGGGCTTCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCCAGGC
+
?HIIGHHI?HEHFAGIHDA@GGH7@AFDBHBFFFG?FIFC?@E?F@BAEDDBGEH@FCEHHHABFB@FBGFIAHI?GBHGAG@@DGEEEAID?CICA?G?
@>chr21:9432052-9432146-3
GCGGCGTACAGCCTGGGTGCCATGGATCGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGCCCCACCTGCAGGCTAGGC
+
H?BIIGB@FAGBDAAGCAEIFEECCAF)?GDBDHF?BF@IAD@AH?A?FCI?ED@EDCBIGAAFCFDI?EIDIG@FBG@@F?AAAG@FEABBFBHHBCHD
@>chr21:9432052-9432146-4
GCGGCGTACAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGCCCCACCTGCAGGCTAGGC
+
GB@?GFCCFDGI@?DIDF0BG@?ED??BHG@BEIDFGDIDAF?I?I@@DED@A@HCGAGDACB@AABEIDGCEBHIBICIC@C@?I@IGDAGBBBAFCFI
@>chr21:9432052-9432146-5
GCGGCGTACAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGCCCCACCTGCAGGCTAGGC
+
ED?II?GG?DHG@IAD@CHAGC?@?BACDFDFC@HDHFC?FCBIDFCDEFG@DEIEAEBHEF@ECAFFGF@@GADIG@BHHEDIE@FIGGDFICDAHIC@
@>chr21:9432052-9432146-0
TCAGACGGTAATCAGCCTTGCCTGCAGGTTGGCCTTCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCC
+
H?F@*@EEH@H?@EFFHI.FCHDBAIEC@(HDIDHF@E@CICG@BEBIH?E@D@HBH?IIACGEGA?@CIDCD@FBBGGE@H?HIHACCFABAAIDACGH
@>chr21:9432052-9432146-1
TCAGACGGTAAACAGCCTAGCCTGCAGGTGGGGCTTCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCC
+
?HCFFEI?DEE"?BGCFCABDCCC@H@GBHBHEFD?ADDDICCIFDB?IIBHI?BFEIHBBBFEIEHIGBDH/GIHE?IAEE@EGFDCAD@@FHGAAFHC
@>chr21:9432052-9432146-2
TCAGACGGTAATCAGCCTCGCCTGCAGGTGGGCCTNCACTGGGGACCCATCACCTTCCACCCAGGAGCCTGTCTGCCTCCCACAACCATCCATGGCACCC
+
ECBGGIIDAA?C@E@C?H0GAEF?HG@BFAIB;AI9F?A?BEEBHGGBECBAA?E?H@EFBADICFIGEHHACAH?FAHD@FFFIIF?BHFBC?AIF?@I
@>chr21:9432052-9432146-3
TCAGACGGTAATCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGCCCCACCTACANGCT
+
CAAGGA@@HFCDEABD@EBIEAEBBGCCD@I?BIAIDDHB@H@FDABF?@IBGBGC@D@IACEID?FGEICIGEAEACB@GGA@IFIIB@ABE2BD-IFI
@>chr21:9432052-9432146-4
TCAGACGGTAATCAGCCTGGGTGCCATGGATGGTTGTGGGGGGCAGACAGGCTCCGGGGTGGAAGGTGATGGGTCCCCANTGAAGGCCCACCTGCAGGCT
+
?EBE@F?EIGECFDCGBEDFHBEC@?AIGHCADIAIFHGA"EBCHEEHAHGEGD@=G@ADDH@?DHAGCH@IHGD?I@I2HCAIA@F@HBDD?CIDHCAF
@>chr21:9432052-9432146-5
TCAGACNGTAATCAGCCTGGGTGCCATGGATGGTTGTGGGAGGCAGACAGGCTCCTGGGTGGAAGGTGATGGGTCCCCAGTGAAGGCCGACCTGCAGGCT
+
H@HFCE4HIBGE?@D'AACE@@C@AFHIBBAHCHCDCEHEGCBBACIEG?BHABBAIIHBACEC/CF?EDF?BHD?@@BDBBGBEF??2DCHAB?C?@@I
@>chr21:9432384-9432471-0
ACCACTATGTCAGCAGGAAGAGGTGCCTCCAAGCCTGCAAGGGGCAGNGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAGA
+
IFA@@@??BHECEFEEGCIHABFGCICAD@CBEAEIBCIIGAGCHBE)AEFG?H?CGB?CGI?BFH?A@B?IACED@C?@HG@BACDBBH@IAA?IFFHI
@>chr21:9432384-9432471-1
ACCACTATGTCAGCAGGAAGAGGTGCCTCCAAGCCTGCATGGGGCAGGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAGA
+
BE?B@CF?H?HFFIBBCCFBDIEBIGDGHEGC?GHGGAE%BEGGEIAECDGIEF@HDADEGCD@ABCCIFFEFBHFH@AG?@AGGHA@CBCICBECHDBF
@>chr21:9432384-9432471-2
ACCACTATGTCAGCAGGAAAAGGTGCCTCCAAGCCTGCAAGGGGCAGGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAGA
+
HCBHAGBEBGD'E?A@G@F*@A@DAHIGBB?DC@?E@HICIII@FCB?FBGF?GD?AF@CAGE?IEDDICDHFF@@D@AGIHIBEE?B?HDHFDIC?@AG
@>chr21:9432384-9432471-3
ACCACTACGTCTGCAGACNCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCCTGCCCCTTGCAGGCTTGGAGGCACCTCTTCCTGCTGAGA
+
ICB?FCB,@B?AA@?H@I#FDEGBFE?GC@ABBEIFIBDFGA?FA@@AB?FIDECDDEFBCEH??@HH?AIHHIHABDDEHEAFH@HAIGDEC@BDABFI
@>chr21:9432384-9432471-4
ACCACTATGTCTGCATACTCAGGCCTCCCTGCNCTCTTGGGGAGNCNGGGAACGCCCCCCCTGCCCCTTGCAGGCTTGGAGGCACCTCTTCCTGCTGAGA
+
HH????BGDCI?A?F=ADGC@IGEHG?@G@EG5G?HHD@BD?G?$?9BC?@FFDCGGEEFDGECAIAEEC?DD?EC@DE@HDGFHE@BCCEEHE/HECHA
@>chr21:9432384-9432471-5
ACCACTATGTCTGCAGACTCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCCTGCCCATTGCAGGCTTGGAGGCACCTCTTCCTGCTGAGA
+
HDIHIE?@AIFC?FCG@FDBIHIGG@GI?CBIGEBE@HCGGCAGF@GABBHC@CDHA@HICHCCBG>DD?CBAEFECBIBA?EIIGAHC?FEGEH?HF@C
@>chr21:9432384-9432471-0
CTCATACCACGCAGCAGGAAGAGGTGCCTCCAAGCCTGCAAGGGGCAGGGGGGGNATTCCTAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAG
+
FDEFHC@ADDEGGCBBED?@FBHHEFD?HAIHBIGEFHBHDCIEIEEIF@FFEB!=B?BA(@@FDFDF@?@ED?AI@?IGDA?GCIAGCH@7EG?CGCDE
@>chr21:9432384-9432471-1
CTCATACCACGCAGCAGGAAGAGGTGCCTCCAAGCCTGCAAGGGGCAAGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAG
+
EHEBCIEBEDF?IEAHBCBIGEC9GAIBEHIE?DEIDCCAHHA@HB??HC?BHA@DBII@F?GGBHGDBCGAAII@F?DGCFCCHDIFDFAH???CB@?A
@>chr21:9432384-9432471-2
CTCATACCACGCAGCGGGAAGAGGTGCCTCCAAGCCTGCAAGGGGCAAGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAG
+
@E@AFDBD@HDFAEB>C@DF?EBDIIGIIBF@IGI@ABH?IIB@FCHHBH?CAEE?EEFCA@HHFG?EIIHA@@FBBBGF??CDBEFEHGIBEHDHIFDC
@>chr21:9432384-9432471-3
CTCATACCACGCTGCAGACTCAGGCCTCCCTGGACNCTTGGGGAGCCTGGGAACGCCCCCCTTGCCCCTTGCAGGCTTGGAGGCACCTCTTCCTGCTGAG
+
DAA@IHGEGHC?GGIICGHGH@FEAACFIDCE4DB)@FF?HCCHIA?CGC=IFCFIEACBBDF?GCCEG?FIH?GI?BI?CGGDFAE@C@IIAGHCB@/G
@>chr21:9432384-9432471-4
CTCATACCACGCTGCAGACTCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCCTGCCCCTTGCAGGCTTGGAGGCACCTCTTCCTGCTGAG
+
'CCDI@A@?F?BFIGDBCIIADHGHF?BDEG@DHAAIE@DAAEAEHGHAGAB?D?IDA?GADHEEB@EFGEDBA??G@IFFCEB@A?IC?FIDDACCG?E
@>chr21:9432384-9432471-5
CTCATACCACGCTGCAGACTCAGGCCTCCCTGCACTCTTGNGGAGCCTGGGAACGCCCCCCCTGTCCCTTCCAGGCTTGGACGCACCTCTTCCTGCTGAG
+
@B@BDAAHB?I?@ADIECIBICCFEHG@?FCDH?A?@HFE5?H?HGHEFF??DHGED?@BGGII'CBI?G9HHBEDG?DD?5?AGDA@GD@GEIHGEDDI
@>chr21:9432384-9432471-0
GAAGGTCCTCAGCAGGAAGAGCTGACTCCAAGCCTGCAAGGGGCAGGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAGAT
+
BCHCFIAGEBFC?CCCCE?FE=?D"IDBBA@I?IIE@@FDHIH@FGBFGGG@?D@BBH?DBHGI@??DEEFFF>A?BDB?EBFG@HAD@HCIDEEBEAHF
@>chr21:9432384-9432471-1
GAAGGTCCTCAGCAGGAAGAGGTGCCTCCAAGCCTGCAAGGGGCAAGGGGGGCGTTCCCAGGCTCCCCAGGAGTGCAGGGAGGCCTGAGTCTGCAGAGAA
+
D?GIEGHFBEIBCIHH?G?@CF@BCBFGEIH@ADIBC?HIIAICCGE@@BDG?EGA@IGGBGEI??AEA;EDI?A(I?DFBFAH?HGDG@GACFD?GA&3
@>chr21:9432384-9432471-2
GAAGGTACTCAGCAGGAAGTGGTGCCTCCAAGCCTGCAAGGGGCAAGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGAAAGGCCTGAGTCTGCAGAGAT
+
FF@?FH;BICH@HHHFC?E+GIFGID?BFB?BECC@GHDIECHE@HAGDB!EG?DDB@B@C?GAHBIDHH@@CGI6?C2)IFFAHGD?IDD?IDB@?@ED
@>chr21:9432384-9432471-3
GAAGGACCTCTCCAGACTCAGGACTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCTTGCCCCTTGCAGGCTTGGAGGAACCTCTTCCTGCTGAGAT
+
AHFHC=@HEA@%A@CAABAABC5BABGEGE?CIEAGG@BGIHCEHGC@HEA?HEG?@@BAABD?D?F@FGEBGICHDGDFA*C??HBD@AEAH@FF?AEI
@>chr21:9432384-9432471-4
GAAGGTCCTCTGCAGACTCAGGACTCCCTTCACTCTTGGGGAGCCTGGGAACGCCCCCCCTGCCCCTTGCAGGCTTGGAGGCACCTCTTACTGCTGAGAT
+
A?BFIH@?/HIHGIDGIDC???;ABDD?D+GHGHBF@GFFGFECEAGG@E@FHBGDE?EDFHIDFDGI@D@@BCADA?CFFAEEGHB@@$HCCAGFE@GD
@>chr21:9432384-9432471-5
GAAGGTCCTCTGCAGACTCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCCNGCCCCTTGCAGGCTTGGAGGCACCTCTTCCTGCTGAGAT
+
CIHDIAGFHFEIAI?IEE@?HEAABA?ACDFHCIHAID@@DIBBAFIFI?HBI@HBGHBH:EBEE@?F?AFAIDHAED?E@@CEIIHHEHFD???GBACC
@>chr21:9432384-9432471-0
GCGGCGTACAGCAGGAAGAGGTGCCTCCAAGCCNGCAAGGGGCAGGGGGGGCGTACCCACGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAGATC
+
BB@AIEHFCAGBB@?GHGEDDFIBFCCAHHHCH$@DCHACIFDEEBAHAC@DFB9CIHH*GC@AEFHCBHB@FEAAFBEGDDFEDF@@D@BA?CCHBHAA
@>chr21:9432384-9432471-1
GCGGCGTACAGCAGGAAGAGNTGCCTCCAAGCCTGCAAGGGGCAAGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGAGATC
+
E?EHA?ECHFID"EE?@IA@(DFDEAIC?ADDE?EDBBCGI@AICFED?G?I?GDC@EEGDIFID?IDEB@@@CFIAGFHADDGGEB@FDHBBCH@EH?F
@>chr21:9432384-9432471-2
GCGGCGTACAGCAGGAAGAGGTGCCTCCAAGCCTGCNAGGGGCAAGGGGGGCGTTCNCAGGCTCCCTAAGAGTGCAGGGAGGCCTGAGTCTGCAGAGATC
+
HECEG@BGB?I?IEB?D@CECFGDAEACBHIBBGEA"H?G@BGBF?FEHAI@CH?A'CGF?FBA@G8EGIIEBFF@IB@??HH@CFCGACFCI??CH@D?
@>chr21:9432384-9432471-3
GCGGCGTACTGCAGACTCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCTTGCCCCTTGCAGGCTTGGNGGCACCTCTTNCTGCTGAGATC
+
BHFBGDBG@IIA@<?FD@FA:IADDFCGHDF?@IIIIFEGIB@DG?EGB@FC?I?IFIHBH@FHB@H?FDECIHHCC+HCCEIHAHDE&@@ADFD@BD?G
@>chr21:9432384-9432471-4
GCGGCGTACTGCAGACTCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCCTGCCCCTTGCAGGCTTGGAGGCACCTCTTCCTGCTGAGATC
+
CGG@IG?A@F@GFGEHEIDEBDIFAAA?BBDBF@AFAHFAHDICHDA@?F@HI@IECDIDGHDAFDDDI@HF?FIDBIAFICHBI@C?IA?ACICDD?IH
@>chr21:9432384-9432471-5
GCGGCTTACTGCAGACTCAGGCCTCCATNCACTCTTGGGGAGCCTGGGAACGCCCCCCCTGCCCCTTGCANGCTTGGAGGCACCTCTTACTGCTGAGATC
+
GCFHF%HIGHHCCAD??FHI?CEFDE%?4GIIBDCB@C?E?BFCE@?CAHA@FEIDGFACEIBCB?GEDG1FF@FBHE!CD??E?EH@2EEDBAHEI?AA
@>chr21:9432384-9432471-0
TCAGACGGTAATCAGCAGGAAGAGGGGCCTCCAAGCCTGGAAGGGGCAGGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGGAGGCCTGAGTCTGCAGA
+
HEGAFG?BC?F?ABIB@HBB?GFIG2DGHEFDCGA@CDA1D@DD@II?BDCC?AFECBBDEFGIC?CGCDFBACCC??AG?F@@EHBGGEAIDD??CCBI
@>chr21:9432384-9432471-1
TCAGACGGTAATCAGCAGGAAGAGGTGCCCCCAAGNCTACAAGGGGCAGGGGGGGCGTTCCCAGGCTCCCCAAGAGTGCAGGNAGGCCTGAGTCTGCAGT
+
IIGCCB@FC@B@G@?AIA@GBAI@GAEEG,DBEFG;DI)E@H@BG?@E?DDC@IFCHCGCD@IBDEEAFADEFHEEAEHDHI-IDD@BA@@BFFEECHG&
@>chr21:9432384-9432471-2
TCAGACGGTAATCAGCAGGAAGAGGTGCCTCCAAGACTGCAAGGGGCAGGGGGGGCGTTCCCAGGCTCCCGAAGAGTGCAGGGAGGCCTGAGTCTGCAGA
+
HFIFE?HAFBGHCHG?GHFGD?DCDGGFHA@FF?F-GEBABCF?A@BBCHHC@?AEDFB@DAEIIFHAHH3D?6E@@EEHBF@FGDI?IE?EECF@EAGE
@>chr21:9432384-9432471-3
TCAGACGGTAATCTACAGACCCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGNACACCCCCCCTGCCCCTTGCAGGCTTCGAGGCACCTCTTCCTGCTGA
+
@GBBCBCBD?EBBD2BDAFD7BGEBACGAE@??F?FFGIAII?HAFFCF?FG&BE1IEBE@IEI?F?@I?DG@D?ACHE)F@AD???H@GFFIGDAIBDI
@>chr21:9432384-9432471-4
TCAGACGGTAATCTTCAGCCTCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCTCCCCTGCCCCTTGCAGGCTTGGAGGAACCTCTTCCTGCTGA
+
@BEIFEDE@I%GHI>CBD7CIBI@B?C?GCD@?IAHAD?EGDDFA@BEFBD@II?CDE5D?@ECDGBICEH?E@@HDEEC@HID3DG@HCC?EGH@GCCH
@>chr21:9432384-9432471-5
TCAGACGGTAATCTGCAGACTCAGGCCTCCCTGCACTCTTGGGGAGCCTGGGAACGCCCCCCCTGCCCCTTGCAGGCTTGGAGGCACCTCTTCCTGCTGA
+
DI?@GAFEBD@DBBIDHFI???ECCHIGFBI@GD?G??I?AFIDBGH?GEBII?B?GG1HDAE@ICGEFFEFEABGHACGH?FCDA@ABIHCDIEB@H?B
@>chr21:9432468-9432581-0
ACCACTATGTCAGCATTGGTTTGGGTAGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCNGTCTGCTCCATGGAGTGGGAG
+
GACHFBGABDGAB?DBIDHIHGDCFC@BH/DD5FEIDHADEDAH?DABCGCA?G@IC?GGBBGFD@FGAEGFAIB?GE2GHHF@CEDG@FGBBCAGIBHD
@>chr21:9432468-9432581-1
ACCACTATGTCAGCATTGGTTTGGGTAGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTNGCGTCTGCTCCATGGAGTGGGAG
+
D7H@FEGCIEGCCGIGBHIH@?B@DF?C?BCA?AHICAG?@C?CFBFIGEHFB?IAEBH?F@IBHH@AC@EDGHBC8!FBDFDGBAFEBH@@@AIGACFF
@>chr21:9432468-9432581-2
ACCACTATGTCAGCATTGGTTTGGGTAGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGACTGCTCCATGGAGTGGGAG
+
?HBHIC?DDH?@A@CIIDFB?EGBEG@BFCHFCHCDGF?FIBAB@IFFADEDFCCDAF@DGDCD?ACABIEAAFCCBAI@,I@DCECBCC@F@GFDGCAC
@>chr21:9432468-9432581-3
ACCACTATGTCAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTCCCCACCCTAGCCCACCA
+
D@BBCG@FCACDF@ACBF@IDF?FB?DHAG@?IDGFHF@@@ECH?CEDCF?CBIAAIHADDHEBBDEI?AGF@FIBE??AEIDFEDC@?@H@ACFEA@AD
@>chr21:9432468-9432581-4
GCCACTATGTCAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATACAACTCCCCTACTCTGTCCCGACCCTAGCCCACCA
+
2FGIDFEF/DAIAHBAEC?HCB?DEHECEE?BGA@AFG?GFFC??FFCA?IBAA?IEAEB@FIC1FA@HADDDGGGCAFHDG?ED$GACABI?ICGDDFC
@>chr21:9432468-9432581-5
ACCACTATGTCAGCTGTAGCTNTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTCCCCACCCTAGCCCACCA
+
ICEFD@AHA?DECG?IFCEA?.GIEC?DEFHBFEHD?HDE?GAAEAHAEFFFEIH?DGC??GAFEF?GCADIDFBHI?FFIGFGEHEI@IDDCF?ECCAI
@>chr21:9432468-9432581-0
CTCATACCACGCAGCATTGGTTTGGGTGGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGGA
+
@IC@IIAE@HB@HDDE@D@D@AACBIGHIHBF@BACHHFACHG@@IFFCGAAEFEFDG?GBDC?D@E?FIA@GC@FGBCEDDIIFB@EB?GDDG@ADBB@
@>chr21:9432468-9432581-1
CTCATACCACGCGGCATTGGTTTGGGTGGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGGA
+
@BAHEBHCDCAF0AH@DGFAI?BHHCIGGEIC?EC@CBED?ADHDI?FEAGEFG@EE?DA@ED?HIIC@DE?@HHI?HEABI@ADIDF?GIHG@DCCHFE
@>chr21:9432468-9432581-2
CTCGTACCACGCAGCATTGGTTTGGGTGGCTGGGTGGTGGGCTAGGGGGGGGACAGAGTAGGGGAGTTGGATAACCTCCCGTCTGCTCTATGGACTGGGA
+
DFG%DDBDIDDBGADCE?HAEC?BGBGGIG@EAHFA?IIBFAAIDA?3HAEG??GFBEC@CBCFFHGC@E@GIA-D@BB?HIAFC@HI+DD@?@"CDCEG
@>chr21:9432468-9432581-3
CTCATACCACGCAGCTGTCGCTGTAGGCCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTCCCCACCCTAGCCCACC
+
ABEGEG@DACIC?DH?BF8DG@FDGC;DBABECIACCAHADFIH?EBCDCB<IGFEBHGGFE@CIBHEGCCEA?@@GAII@FE@GFDACE@EDDIDD@$A
@>chr21:9432468-9432581-4
CTCATACCACGCAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTTCCCACCCTAGCCCACC
+
HAGGIHAC@D?GCFDCDFAAH@GAAAAEGEGCD?DFE?B?@GAIBDCICAGGGBIH@HIHECG@@?@DE@??GIF@E@?FEBB3E?DD?GIEAAE@HEDE
@>chr21:9432468-9432581-5
CTCATACCACGCAGCTGTAGCTGTAGACTTGGACCTCCCACTCCATGGAGCAGACGGGACTTTATCCAACTCCCCTACTCTGTCCCCACCCTAGCCCTCC
+
IG@ACE@GDCGI?E?GIC?HEBGHHHH@-CHH?A?DI@FH@H?F?HE@@E??DAEE?E@!G@I?CECDIGIH@FDF@A@@E@?DFFFEIBFHGABEG8H?
@>chr21:9432468-9432581-0
GAAGGTCCTCAGCATTGGTTTGGGTAGCTGGGTGGTGGGCTAGGGNGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGGAGG
+
CDDGI?CDACACIHD?ADBAGFIEEEHIAABFEEAGCBDE?C?I?/?II??HHBFDHHDBG@GHDDDFII??ICIGIHFI@GAEEFIIABEHABEGBCFI
@>chr21:9432468-9432581-1
GCAGGTCCTCAGCATTGGTTTGGGTAGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGGAGG
+
A>CF??EBHGEFACE@ECBFFDFCI@CC???HBGI?DBE@G@CAIDHICACE?IBGDDHDHH?AEIBEGE@B@F?CE@D@CFGHAG?A?HFBI?FHDIHF
@>chr21:9432468-9432581-2
GAAGGTCCTCAGCATTGGTTTGGGTAGCTGGGTGGTGGGCTAGGGTGGGGACGGAGTAGGGGAGTTGGAGAAACTCCCGTCTGCTCCATGGAGTGGGAGG
+
GFBIAHFGGAH:?CBH?@??AB@HA@GB@AFDEDH?EBCB@@GA??DGAEFB>@EFHH?AGIHHFDDG@7HCFIDAEFGHGCH@BFF?EDADEFEGADHH
@>chr21:9432468-9432581-3
GAAGGTCCTCAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGTCGGGAGTTTATCCAACTCCCCTCCTCTGTCCCCACCCTAGCCCACCAC
+
??@FAIABHAIH?BE??F?@CGDICFCECIEGBDAF?EFIE?IIF@CD@HF'FAG@@GABG?IEHFBEHB@?BF;E@GFIBADBHGCBHCAHGHDECAGH
@>chr21:9432468-9432581-4
GAAGGTCCTCAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTCCCCACCCTACCCCACCAC
+
B@FBHD@@HBDDDCA?BHIBEFHDBBIC@HCEIF?HDAEG@FEA*DGBH@HFFBHIFCIGBDEHAICC@A@CHIA?HH@H?HIB?G@GAHF"ED@EGDCC
@>chr21:9432468-9432581-5
GAAGGTCCTCAGCTGTAGCTGTAGACCTGGAACTCNCACTCCATGGAGCAGACGGGATTTTATCCAACTCCCCTACTCTGTCCCCACCCTAGCCCACCAC
+
FEBEGHB?DFCGADB@AFE@EGIDBFG@@A?6F?A;?AAAIFGHHBBF?@IE?IHI?3?ABAIGEFGHIG@HI?GI@@EGI?DEAD?FGGEBC?IGFCHA
@>chr21:9432468-9432581-0
GCGGCGTACAGCATTGGTTTGGGTGGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGGAGGT
+
BCD@HFDEBGDA?AFFHIGHEIF?CGI?EGAIB@0FCDGCHFED?GAADGE??FC@GBBGCDADGHI@CBGFEEAEFC?GC@HGID?EABC?EA?HBCDD
@>chr21:9432468-9432581-1
GCGGCGTACAGCATTGGTTTGGGTGGCTGNGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTGCCGTCTGCTCCATGGAGTGGGAGGT
+
HDGDIGHGCI?BGCD?HEEHIFB@FFFB?0FIB?DFGDHEDHHGHGCHH@FFFGHEDGAEDHFF@BBHAAGCEI*CEE@GBB@EBADFHDCAIHD@GHEI
@>chr21:9432468-9432581-2
GCGGCGTACAGCATTGGTTTGGGTGGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGGAGGT
+
??ACBCDIBBAACDIA?H@DHHFEAEFDEG?IBHGDHDFBBG1@ECGFDDC?HDHB@IC?IEE??GGIBGHBE?EGBGBFFF@G?BI?@A@ABGFEE?A@
@>chr21:9432468-9432581-3
GCGGCGTACAGCTGTAGCTGTAGACCTGGACCTCACACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTCCCCACCCTAGCCCACCACC
+
FA?HIHDABBCAFADGDEFDI?!BI??FFABF?H2GHBCGIBEFF?DIEFC@ECBDEAEF?CCB@IICHF@ECHI@DHEIDHIDDCFEGAF@FHEDGIDA
@>chr21:9432468-9432581-4
GCGGCGTACAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATACAACTCCCCTACTCTGTCCACACCCTAGCCCACCACC
+
AICHCH?BEIHIEFEHCDGC@H@@IDDCHI@F?DGICAB?@CDFHGHIA@?GB?FFDIH@IE4A@IAG?@IAACDIAG@GGC<DFGEHHHCH@DHGFIIC
@>chr21:9432468-9432581-5
GCGGCCTACAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATNGAGCAGACGGGAGTTTATCCAACTCCACTACTCTGTCCCCACCCTAGCCCACCACC
+
?CF@@.@HHBBIBFC@HDC?ICDEBCAHIDFDFFGFAE?EGID#ICB@FCHICAFBGH??CAGFCBFHBD*E?CHAFAG@DHDAFB@AD?AHEEGCB@I@
@>chr21:9432468-9432581-0
TCAGACGGTAATCAGCATTGGTTTGGGTGGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGG
+
DCABB@FFE@E?BFAA?BDBFI?GGHIEICAGDACDHHIEDIG?G???H@GFEBDCGAH?BG@I@EDE@IFGDAICDC?DGHIAFGAE?IG?@FI@AAFF
@>chr21:9432468-9432581-1
TCAGACGGTANTCAGCATTGGTTTGGGTGGCTGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGGTGGATAAACTCCCGTCTGCTCCATGGAGTGGG
+
ICD?@D?DDF)DGBHIIFCIGE@?EAF?BFDCFGHBIDCAACGBG@G?GHFDECIFHIFF@F?BBEC!GIIDGDIG@BHBDIBE?EIEBIECHGFAAHIE
@>chr21:9432468-9432581-2
TCAGACGGTAATCAGCATTGGTTTGGGTGGCGGGGTGGTGGGCTAGGGTGGGGACAGAGTAGGGGAGTTGGATAAACTCCCGTCTGCTCCATGGAGTGGG
+
EIDBCCAEBBIFFGIFGGADDIHIHI@?BDA5DA?EDGH@DAAGGBFCBHBIACB?FDECIDHCACBEADDI?GGAEA?FBCEGB?BGIBAACEB@HBFG
@>chr21:9432468-9432581-3
TCAGACGGTAATCAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTCCCCACCCTAGCCCAC
+
@FI?CHHDGFD@?BI?EGFAEDF?E?IHCIGCFIEICAB@?DFHEEAD@C?C@CDB@?H<EIFFCI?HIB@F@@GGC?BEF?DIDBGBFIDCEHFCBDCD
@>chr21:9432468-9432581-4
TCAGACGGTAATCAGCTGTAGCTGTAGACCTGGACCTCCCACTCCATGGAGCAGACGGGAGTTTATCCAACTCCCCTACTCTGTCCCGACCCTAGCCCAC
+
GD8ED@BHEB@GBHBCAICAGE@CHEH@BA@IGFBHF?FBGGE?GABB@GBCGG@E@ACH@FH@BB@IFEADF?CBFCBCFHA@CHA1IDAACAG@EEB?
@>chr21:9432468-9432581-5
TCAGACGGTAATCAGCTGTAGCTGTAGACCTGCACCTCCCACTCCATGGAGCAGACGGGAATTTATCCAACTCCCCTACTCTGTCCCCACCATAGCCCAC
+
B@A?IBDGBIH?FE@HIHDCIB@FGDBE@H@C$ABF?H@CCDECAG@A@CI?IDCCG@@I*BIB@CIE?H@I?F@GAICEIA??@CDIGAI*@IIDBBIE
@>chr21:9432596-9432707-0
ACCACTATGTCAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGAAGCATACGACCCT
+
HGFABFHAABH@A@A?IDIF?AIA?E?BAEAEF?FIHBBGDHDA?BBB?BIHCGHFCBEACC?G?FFECHCGCEICIIF??BDA?ECEBHHCEE;IHA@A
@>chr21:9432596-9432707-1
ACCACTATGTCAGCAGCATCCAGGGAGCTCCCATTCCAGTTCTGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGAAAGCATACAACCCT
+
@GBHAGHBDGDGAAEEAAEC??@IEDFDG?AECG?D@?$CHC.ICCFHHEGAIHIHDFCICB@@AF?E?GCE?CDH?FIE@GIA?=EIECAAF?@@CA@E
@>chr21:9432596-9432707-2
ACCACTATGTCAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGAAGCATACAACCCT
+
??@F2@FCH?H@GGH@GH@ADGBHGICID@@B@E@EAFBID?GIAADFC@GCDBHC?@CC?IB?GHGEEABFCFCCGAFCEBD?@E?DE?BAIBGADBIE
@>chr21:9432596-9432707-3
ACCACTATGTCTGCAGGGGAGATGTGTGGCCAGGGTTGTNTGCTTCCTGGATTTGGCAGGNTGNGGACAAGTGGGAGCCCTGCCCTTCCGAATTGGNATG
+
AHA@HHFH@?@@FIH@BE?HA?2IEC?C?BGIDIBB?AI#EHHGACAIGDHHCEAAHAED+G@!?EGDFFIDCA@HHA@BB?GBHDAFICDCIGHE-HA@
@>chr21:9432596-9432707-4
ACCACTATGTCTGCAGGGGAGAGGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGGCCTGCCCNTCCGAATTGGAATG
+
D?EHCH;BIHAIBEFEBHD@E?FDBGC@IAA??EGIDDB@ECBHDC@BFADFGDAH?@A@ADBCCH?B?BA@FCCFG*I?C@EFE(BHH?I@HB@BEDEE
@>chr21:9432596-9432707-5
ACCACTATGTCTGCAGGGGAGAGGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCTTCCGAATTGGAATG
+
EEABB?H?CAICEDIIDEE@IBEECAADAE?@ADFFBFIBF@@AEAGIBEFDIIFB?CDABD@@IGA?BCDEG?GDBDCBCEDCGEGC?BCCACEDADHH
@>chr21:9432596-9432707-0
CTCATACCACGCAGCAGCATCCAGGGAGCTCCCATTCCAATACGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCATGAAGCATACAACCC
+
FCICD@ICAHC?GIF?HED?ECIF@GDHEGGGAB?AC@AAG)GFFDHIB?FGA@@EBFDFA?AH?@DB?HHGHDF?C@HEGDDC?:@?FECB@DFFEICE
@>chr21:9432596-9432707-1
CTCATACCACGCAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGGAGCATACAACCC
+
@CEHEIH?FDGBACIHDFIDEFAB?@CBAIEAGGDEIBDDH@GCGFABGFEE?EI@AADCEGBEDHHFBHHGHBC@GA??EFC@@HADIABBE@DECAAF
@>chr21:9432596-9432707-2
CTCATACCACGCAGNAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCANCATGCCAAATCCAGGGAGCATACAACCC
+
@B@GDF?IACCBGH9@EEAC?DEG?D@CEFFCD@HBGDIIFDE?HFF?B?GCIHDEHIIA@ECEHCCDD@F9@>HA?CBAEFIF@DF@AAFIA@C@CBBD
@>chr21:9432596-9432707-3
CTCATACCACGCTGCAGGGGAGAGGTGTGGCCAGGGTTGTATGCTCCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCTTCCGAATTGGAAT
+
HDGCDDGEAIGCHEICABIDCDGCFHBDAA@?DIFGFBF??ADCAHIABDDED@?GCEDFICGIHI@FFHE?EG?DH?B@GH?FFHAGIIBFDEBIIBGI
@>chr21:9432596-9432707-4
CTCATACCACGCTGCAGGGGAGAGGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCTTCCGAANTGGAAT
+
BCEH@IAAIFHDFCEG?E?A@HHHDICDEHCI@A?HABHDGIHI@@D@DEGDABGHEIDEA?BE?B@GACHEI@E?AFIGCBH??EF@DH?AB+HF@HIF
@>chr21:9432596-9432707-5
CTCATACCACGCTGCAGGGGAGAGGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCCTCCGAATTGGAAT
+
G@FEGCEIBGBHFDHHADD@IA@DBFCEG@AEGEF?C@HC@?CDCEDIB@A@I@I??@HE@DBH?@BCAGGI?GGI?GF@E@FFFB7AFI?ACDDGECFI
@>chr21:9432596-9432707-0
GATGGTCCTCAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGAAGCATACAACCCTG
+
HH2D@@CCGI@IEDGHAAH?HAHAHEEGAFG@HGBIIDHADHBCICDBBA?FB?IACEHDI?IAIACFDAEDHB@G@GECIHH@I@IH?AH@BAD>?CAB
@>chr21:9432596-9432707-1
GAAGGTCCTCAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGAAGCGTACAACCCTG
+
AFABIGCE@HA?I@?GF?IIFEED@?;@IDIEGFEHHBHDEBFFDDGDG@?@@E?I@H@ECI@?GFG?I?FHH@AABD?EFFGECAFII3EHADIBCCEI
@>chr21:9432596-9432707-2
GAAGGTCCTCAGCAGCATCCAGNGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGAAGCATACAACCCTG
+
GGCD@ED@GDACIHAGAIHD@G;DAFAD@@GBH?DDAEEI?AAG?DDDFHGEA?CFIBHDGEHFCIHCBEBAFGICHAFAFDDBF?HBBDE@D?DCA@II
@>chr21:9432596-9432707-3
GAAGGTCCTCTGCAGGGGAGACGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGTCCTTCCGAATTGGAATGG
+
E@H?ADICCGHB@BAEIGG@?4AFAEHBIFHHI?G?AEEDAID?A?GBCCFFAIEGIGCDAIDHBE?BA@?ICE@CGGBDH2@FIIBCG??BEIC?IAI@
@>chr21:9432596-9432707-4
GAAGGTCCTCTGCAGGGGAGAGGTGAGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGCACAAGTGGGAGCCCTGCCCTTCCGAATTGGAATGG
+
HF?BG?IHDBFBEBCDGCEG@CCGF+GHHHHBFI@HIAC?CFICDCCHIF@AFCBBF?@GHBAH$H@HHDFGFIIGAFDAICFB?BFE@IDCC?FGCGHF
@>chr21:9432596-9432707-5
GAAGGTCCTCTGCAGGGGAGAGGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCTTCCGAATTGGAATGG
+
CF@??HEIBGEBFBAHHEFDC@?HHIH@G@CC?CAGEGAHEFAEGCDBAA@GAAIHII?DHGG@F?ECGD@ICD?B?HGCFD@BB?G?EFCF@BHDIDGI
@>chr21:9432596-9432707-0
GCGGCGTACAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGAAGCATACAACCCTGG
+
IGAECIACICEEADE?HGCHAHH@CFAH?@C@HID@?AAB@?IHG?FCFF@E??GIBCHFHIEC?DC?A?ED@IBD@A?AC6GFDABAACI?GGCDFD@F
@>chr21:9432596-9432707-1
GCGGCGTACAGCAGCATCCAGGGAGATCCCATTCNAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGAAAGCATACAACCCTGG
+
BHCCCFEFHIE?IBDIGEGHGEDDH=GGIGCEEH-FIE@ICAHGE@F?IHGIEFH?@GAHGDD@@?G?BDFAGIGAFCAFIFD;EEF@CFDG@CADFE@A
@>chr21:9432596-9432707-2
GCGGCGTACAGCAGCATCCAGGGAGCTCCCATTCCAAATCGGAAGGGCAGGGCTCCCACTTGTNCTCATCCTGCCAAATCCAGGAAGCATACAACCCTGG
+
GBGA!FEAAA@DFICGIBBDIC?@@GE2II@AIEH@I$CI@FHA@AHBE?@CBIHGEEE?GFD9FGGCBGAG@EHHGB@IGIEFGI?E@IBDC@@A@GEH
@>chr21:9432596-9432707-3
GCGGCGTACTGCAGGGCAGAGGTGTGGCGAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCTTCCGAATTGGAATGGG
+
BGHDICB@BEGFDBCE5DE@EIGHBIBC7ACAHAGF@IHBCAHF@IBD@DIFEFIAI@B@HIAADDHCAAFGDH?FI?IH@@B@DB?F@DHHBIDH#HBI
@>chr21:9432596-9432707-4
GCGGCGTACTGCAGGGGAGAGGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGAAGGATGAGGACAAGTGGGAGCCCTGCCTTTCCGAATTGGAANGGG
+
EFIHA?AIGGDCIDHEBA??CCHCIE/G@FD@BBBCHA@CC@BCFEGIHE@C?G%C?IIC?EHI?CHEIDGFEH?DIBECDF4EFFA??DICDFEF,FHB
@>chr21:9432596-9432707-5
GCGGCGTACTGCAGGGGAGANGTGTGGCCAGGGTTGTATGCTTCGTGGATTTGGCAGGATGAGGACAAGAGGGAGCCCTGCCCTTCCGAATTGGAATGGG
+
IDEBDFHG?GDGH@@@AEEH4D@EACEDEBFFH?CCEBCH@@IG+FGEDCEDHDHAAFBF?@@GIFG@F5DG?B?H@ADF@HCC?IBAHDEIFEEIGBC?
@>chr21:9432596-9432707-0
TCAGACGGTAATCAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGAAGCATACAACC
+
@ACBCHGFEECGAGDFACAIA@CAICFI?FIFIIDC@B@HFDCH?@D@HCG@ECBIAEHAHHEDB??IB@AI@HGC@IEDA?H@BBD??EHFDDD?AGDI
@>chr21:9432596-9432707-1
TCAGACGGTAATCAGCAGCATCCAGGGAGCTCCCATTCCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTCATCCTGCCAAATCCAGGGAGCATACAACC
+
@F@?HB?BI?BDCBIIIDIGICHGCG@BHE@+DFFE?EBGEBEACGH??DDHCEHHIAEIHGHC@DICIGECEG@GBBDHBBFBABIFAHBC?DDC@CFC
@>chr21:9432596-9432707-2
TCAGACGGTAATCAGCAGCATCCAGGGAGCTCTCATTTCAATTCGGAAGGGCAGGGCTCCCACTTGTCCTGATCCTGCCAAATCCAGGGAGCATACAACC
+
IA@IIFCCHADEHEHG?E@CGFGHF?DDCFFG3GCIE&IBDDACI?CI@BHE?GA@EBEA?CG?EEA?EC%DGDGBEAI@ICAFCDDAHID?HCF?HFCC
@>chr21:9432596-9432707-3
TCAGACGGTAATCTGCAGGGGAGCGGTGTGGCCAGNGTTGTATGCTCCCTGGATTTGGCAGGATGAGNAGAAGTGGGAGCCCTGCCCTGCCGAATTGGAA
+
F@GHHGHAEDGI@@DAEFI@F?D=GDEIFD@ECBH1GII@H@ECII?CIID?@AGFBDIFDB@GAHF>E#A@FDED?@HEGC?DHF?H>GEIEB?FC@FH
@>chr21:9432596-9432707-4
TCAGACGGTAATCTGCAGGGGAGAGGTGTGGCCNGGGTTGGATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCTTCCGAATTGGAA
+
AFBABGBB@DEEDEFI?CBCGBG?IBIDE?A?G1FDIIBG$HAIIDE?FBC@GDDFD@HEHGGHACG??BAA@G@BGCAHECBG?BHIBCDFAIAIF?D@
@>chr21:9432596-9432707-5
TCAGACGGCAATCTGGAGGGGAGAGGTGTGGCCAGGGTTGTATGCTTCCTGGATTTGGCAGGATGAGGACAAGTGGGAGCCCTGCCCTTCCGAATTGGAA
+
@CAGBIID9ACG?DE'?@HIIIDC?EHEGDAFI?FIBBGHCDDFBD?EG@FCAI?C@D?BHCHA@??CEDGEBEC@@EEIDIDGGDDIBD?E@C?BHF?F
@>chr21:9437640-9437782-0
ACCACTATGTCTGCCGCGGCTTTTTGCGCCCCNCCGCGGCGACTTTTTGCTACCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCCGTTTTTGCGGCTT
+
I?DFIFHCAICDCDDB?@DEDA?IFAHEH@CE/HADIEEE@BDBGG?DAEG4GDECFCC@G?@AA@CE?CII??@BFFI@ED?CHE=?GCEE@BDHHHAC
@>chr21:9437640-9437782-1
ACCACTATGTCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTGTGCGGCTT
+
IG?DEE@HBCHBAHBCC@GADBEDDICFHB?CFH@?EFC?GACDB@CDCEBFECBIEDGEBB?D@HA?EFGEDFGC?DDH@DEA?@CHCGA<@@?IAIH?
@>chr21:9437640-9437782-2
ACCACTATGTCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCGCCGCCTCCGCGGCTTTTTGCGCCNCGCCTCCGCGGTTTCTGCGGCTT
+
IG@ECCFIDDAIGHDDIF?IG@EGEHCEBHAA?EDFE?ACCFFFEDE@IIDC-H?EDHGBCAIGC@@FEE@?B@D?"BEIB:EFH?@HECF!CFCFBA?C
@>chr21:9437640-9437782-3
ACCACTATGTCAGCGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCGGGGCGCAAAAAGCCG
+
@H?A?EIFDFEFGGDI@DHCFHIC?EICBHIHHI@D?ABADCA@ICFEAE@IEEFB?BIE@AFDFDHHEGFCGEA@@BDBEIAIEHFI?BH@CCED?BDD
@>chr21:9437640-9437782-4
ACCACTATGTCAGCGGGGGGTAAAANGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCGGGGCGCAAAAAGCCC
+
FHCAB?FHII@CHDCHIBGIGI?FG"DDAIFBFG?B@DFHBGDIA@IDBFHA@FABDBBAEFC?DA?F?@EF@CGIAHGDIE@BHCFABGFFFE?HDFE:
@>chr21:9437640-9437782-5
ACCACTATGTCAGCGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCGAGGCGCANAAAGCCG
+
?BFB@HBBHA@A??C@@GAAAEDBGB?HC?C:EEHACBGFDHGCEE@F?HIID@CAC?@H?G?@FHIBIBII??H@BF?ABIEDF1IH@G@@)@FFCCCI
@>chr21:9437640-9437782-0
CTCATACCACGCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCACGGCTTTTGCGGCT
+
G?DF?BC@@EBEF?@@FI?GDAG&??ADEBCGIADEDBFEBBEFDIHHGBHH@IH@BE?ABE@@DAIHBEGG@BEFFAH@AHHFI3CIB"H?HEB@DFFE
@>chr21:9437640-9437782-1
CTCATACCACGCTGCCGCGGCTTTTAGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGCT
+
?H@GBG?HIGCBCDI?DIHDD?IEI2EAA?BBGDFDIDCC?G?IBIF@?IB?BFDIFBED?DDDE??DH@H@AE@CGAFFE?FE??DB?BFBGD?CH@GE
@>chr21:9437640-9437782-2
CTCATANCACGCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGCT
+
GFI?AI'HGCGEAHGFFE@HBBFE?FFCDIFHCIFF?@H@BFD@EAGFEBAH?C?EEAAIBHGHIG#FFAFIIB?EFBDHCIFCBEBI?EHFIEIEEGGI
@>chr21:9437640-9437782-3
CTCATACCACGCAGCGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAATACCGCGGCGGCGGGGCGCAAAAAGCC
+
IGG@EEGCGFFIAEEIAIGGH?DDE?E@?B?@FIIEE@EBDEGCF@FBD?B?GHHIIB@B?FHCC?B?F@BIC>GHBBCDDC@?D?@EGA?@DIDGIA@D
@>chr21:9437640-9437782-4
CTCATACCACGCAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCGGGGCGCAAAAAGCC
+
CDEAFGDIEHIG?G@DDHGGEDAGFCDECI?@?CDHGAEFI@GGFDCFFE?FEDCDGGCFIFHFIF?EHGGCBCFD?GIIB?CDIBD?B@?@@@?FEDIA
@>chr21:9437640-9437782-5
CTCATACCACGCAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGTGGGGACCAAAAAGCCGCAAAAACCGCGGCGGAGGGGCGCAAAAAGCC
+
FCHBG?BB@II?FBC@FC@H@FBDHIGCABBH?GABEFFGFI@E@IHIIGG@)CFB?BCIG?@@AHEICDIEAEAHIDFHEGHA1@IDGCHGF?BDABEE
@>chr21:9437640-9437782-0
GAAGGTCCTCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCACGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTTCGGCTTT
+
CEFBBEAAEBIIG?DCE?BDDEBFICCA@DA@G@@FGDGAI@DADGBAA@I@HGGDHGE@:BHCCCGEDHID?GFIDGDCC@@@EE?DEHB@(@FDFCIC
@>chr21:9437640-9437782-1
GAAGGTCCTCTGCCGCGGCTTTTTTCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGCTTT
+
FABEAF@B?EBEGACBDDAC?@IF/IBEDAIAHI@ICD@B@B?G@EFGBAD@G???AIGBFGH?CA@EADFEGFFDBDICC7AIHFDG@EBFE?DAFDG@
@>chr21:9437640-9437782-2
GAAGGTCCTCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGCTTT
+
CEBGCICFGICDID?A@F?DIF@HEAAH?AFDBEAGG?CC?@D?AGA?IF)EICEEIFAHB?BHA?CBFGIC@IEBB?BCIIGHIHGB??FD?ABBFH@@
@>chr21:9437640-9437782-3
GAAGGTCCTCAGTGGAGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGTGGCGGGGACCAAAAAGCCGCAAAAACCGCGACGGCGGGGCGCAAAAAGCCGC
+
C@CIF?GGGIH@AFG"B@ADACA@HIFGCI?@CE@@?@I?I?AG@GD/@DCCGCF@D@IBFGFBCDBA@GADCCBEDC:HBDBF@?@CCA?DEFAFEAIF
@>chr21:9437640-9437782-4
GAAGGTCCTCAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGACGGGGCGCAAAAAGCCGC
+
BG?GACIGBI@@CG@BEBBBFIC?B?DCFFAE@C@CE@GBFID?E??FHI@@BFABIGCB?EFHIFD?EDEADBFAH@FEH-DDDF@FF@I?D@EEBBBA
@>chr21:9437640-9437782-5
GAAGGTCCTCAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAATAGCCGCAAAAACCGCGGCGGCGGGGAGCAAAAAGCCGC
+
EDCHDGIF?HCCBECB@AGHIAG?CGBBF?ICCBIBFICB?DGCDHDAHDEDBGGC@GHCE5DGHIAIGD@A@?HDFD?CIDIED?D8DGH?ABECG@HG
@>chr21:9437640-9437782-0
GCGGCGTACTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGCTTTT
+
ADIDGF?@ID?IDFA?IEIB?@@HIEIBECAHFHIIDI??AFEIAD@IIHAF?@HIBI?ABEA@AHG@?IAHA?G?GGCAHFAGC@C?IBDAHFBC@HBF
@>chr21:9437640-9437782-1
GCGGCGTACTGCCGCGGCTTTTTGCGCCCCGCCGCCGCGACTTTTTGCTCCCCGCNTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGCTTTT
+
IBC@I@AC@GA@CCF?GH@@DEIB@@@BGB@DEFE"D@HEICB@DFE?BBIA@HA8GCE??@G?AIAFDGHB?CDIDGCBAC?G@@HG@F@?B@C@GBE?
@>chr21:9437640-9437782-2
GCGGCGTANTNCCGAGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCAGCCTCAGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGCTTTT
+
AC?BIHC@9?9DF?;G?DHE?HIDHHHGFAF@GFDI?HGEDFDAEBAEDEEB2BIGAF=CAAEE@FHFIGBHHCAGECFDG@ABADBHCGFCAD??CHAH
@>chr21:9437640-9437782-3
GCGGCGTACAGTGGGGGGTAAAAAGCCGTGTNGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCAGGGCGCAAAAAGCCGCG
+
BG@DD?GHHHI?IGI??E@DHGAB?EDAEHH2IEFEH?DDA@BAHCHIICCE?ACDFBFBEDDAB?EGEEFGDF?DHIFGGC(EIFCF??BIAIFIGIE@
@>chr21:9437640-9437782-4
GCGGCGTACAGTGGGGGGTAGAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCGGGGCGCAAAAAGCCGCG
+
HH@B@@C@GDAEH4CH@AC?.DC@@DAIEEDHFBBA@GC?DIHGI??BD@IGIFIEAF@B@CHHEG?@ABC@@FF@@IFG?GECAF@BBG@C?EI@FE4?
@>chr21:9437640-9437782-5
GCGGCGTACAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCTAAAAGCCGCAAAAACCGCGGCGGCGGGGCGCATAAAGCCGCG
+
CHCEEDH@EE???CCG@C@EBGGDBIF?FBB?EDFBGBDCG@DGEBCD*I?GGAFEC.ED?@G@BAHHFC?BAGCEDFH@CIFEBHHGF?8AE@IEI@@G
@>chr21:9437640-9437782-0
TCAGACGGTAATCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGC
+
EDIFFH?B?BCIF?IABIAHBGHD@EA?FHCB?CA?IGCAIA?D@BGGFACHGFCCABE??EHE?IAI@AFAH?D?GC@ID?CBGCFIFB?ICGCA?FGA
@>chr21:9437640-9437782-1
TCAGACGGTAATCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTTGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGC
+
FEGA2BBBEFFEEHA@ADH??HFCIHFECHGGDDFIEF@HHCEBACIGAIDA?DEEG@EEIHFDCHIH@?BBDBGB*@FFFBCHFDIIF@AHIIC@IEEE
@>chr21:9437640-9437782-2
TCAGACGGTAATCTGCCGCGGCTTTTTGCGCCCCGCCGCGGCGACTTTTGGCTCCCCGCCTCCGCGGCTTTTTGCGCCCCGCCGCCGCGGTTTTTGCGGT
+
AIG@@ECDAAIHBDFDBIEC?EAEI?H?G?@AAGBFAFGBDBHCIBAIC;CBAA@DGHC?EGE@?H@I@GA@?BGGCC?@EBG@ABABC@BEEIAF?BG>
@>chr21:9437640-9437782-3
TCAGACGGTAATCAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCGGGGCGCAAAAAGC
+
HHA@ABIDCIGEHFDBFEIFB@GDFCFB$HG@GGDEA?BA?CHACGG?GCIAGAF@AG@BABB?GBFI?HEI?BA@GF@FDHDEG@HGG@GFAIHDI?EC
@>chr21:9437640-9437782-4
TCAGACGGTAATCAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAAAAGCCGCAAAAACCGCGGCGGCGGGGCGCAAAAAGC
+
FFECCDFHFDB?A@G@HD@DC?@EADAICDBH@HBDCIABHE@?@AA@?DEFE@ECD@GEABIDAFCGH@GBGEAAGFG?@?IGAI?G?HGGDDGCAHGC
@>chr21:9437640-9437782-5
TCAGACGGTAATCAGTGGGGGGTAAAAAGCCGTGTTGGCAAAAGCCGTGGCGGCGGGGACCAAACAGCCGCAAACACCGCGGCGGCGTGGCGCAAAAAGC
+
?CIEBEH?IHC?EHD@@@BHAH?C@IGAHAFHABBAFAEGIIECIEI@IBGFFICEEII?HIFI0GD@DGEI?@8ID@@F?CAFCH@6IDAAIE?GH@@I
@>chr21:9438140-9438338-0
ACCACTATGTCGGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTT
+
EFEFC?DDECA??FIDGFGFECIH@ICGBA@E?D?@FHI?EIFBFFA@DHIHCI@AGCBGGBBECG?@@DC@@FIHFDDFDAIBHDHDD@EFD@EGBF@H
@>chr21:9438140-9438338-1
ACCACTATGTCGGCTTTTTACTCCCACTGCCACAACTTTTTGCGCCCACCGCCACNCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTT
+
H??AHGBF@EHDHECFBCFECDCFB?BCCHID@4FCAF@H@CAEBB???E@HG@H6EB@DBBAI@BIBG?BEDCGFDGBB@FEBG?F?AHABEA@DDI@?
@>chr21:9438140-9438338-2
ACCACTATGTNGGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTT
+
CBEEE??FE?&BBDBCGD@IAEAAIHCBHDFAFHGFI@BGHGFEFCCAAIEABFAI?FBD@@AGHD@HFD@FAH@EHEECIEEHE@AGBACCI?@AG@AC
@>chr21:9438140-9438338-3
ACCACTATGTCTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAACAAGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGNAAAA
+
E@FEIGEG?EB?AHH?HICDHG@F?CDI?@?CABIDDCAE??EHHDCADA@HAG+BDIF@IDDB?B@F@HIDGHCDCHAHFFD??E@A@@@FDED<GC?G
@>chr21:9438140-9438338-4
ACCACTATGTCTGCGGCGGCGGGGGCCGAAANCATCGGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAAAA
+
GIIBCBA@F?CGDH?ADDBIDHHCHHCAAHH9FAHEAHAA?@@IHEAEGDI@D@?BG@BFHFDFGABBHAEHECBB?HDFC?HE?HG@?DFBGCHDEFEI
@>chr21:9438140-9438338-5
ACCACTATGTCTGCGGCGGTGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAANCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAAAA
+
BF@CDF@GA?EDIH?FFGG+G@@HFFG?GBHCBAFEHD?@IB@BDDDH@ADFFHHFI*GC?AADBAFCG?HH@H@BGDBGEADACFHCIGBAFEBGBCCG
@>chr21:9438140-9438338-0
CTCATACCACGCNGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTT
+
D?IHEABFFCH?#HHEEFEAEHCECBCIADDFI@EA@GGED@IFA@EDHGBHD?FBDF@EAHGFGA@DDHAF@A@GHGCEFHGHCGGBD@C?AD?A@F@@
@>chr21:9438140-9438338-1
CTCATACCACGTGGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTNT
+
CDA?CEF@DDB!DDAG@@AH?D?EAIHBI?BCEEAFFI@C?AII??@AB@DDACHHCGFDF@HD?DHDBICCFEFA@E?BDHHFHF@?D@CCFCGB@C;A
@>chr21:9438140-9438338-2
CTCAAACCACGCGTCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTT
+
?IFD=EFE?CDBF8?FIADE@GGFAGAEGA?CCIFA@G@I?HGCBB?GCC?AFFEFC@GB?EB?AICAA@E@EEGFAI?GA?FBADHHHHIIDIAEDCBF
@>chr21:9438140-9438338-3
CTCATACCACGCTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGAAAAAACCCGCGCCGGCGGTGGCAAA
+
BFH?IDFHCABACI@EB??HEC?AAF@DAIBC@IIIDH@GI@ICHEBFFHA?E?GDCEHIGHEIE?AIHAIGG?ECEEBDADAFDD,IH?EBCDAIDDCD
@>chr21:9438140-9438338-4
CTCATACCACGCTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAAA
+
GEF@F?CBEHDBGE?F@FIBCAF?@F?IIF?B?GAC?EHEE?IBGDAABCE@BHAEIGH?CAA?G??HCGDHCAC@GAFCHFFBDCCHB@G@GBH@I?GC
@>chr21:9438140-9438338-5
CTCATACCACGCTGAGGCGGCGGGGGCCGAAAGCATCNGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAAA
+
DBIIE?HDCFF@@@'B@IEGCFGGIDBGEDIIIB@AB#CDF?BDBBBFBIC?HDBDAEFEFFI@HDBAABBHBIEGD@??EGHAC?I@A?IC@C@ID?IA
@>chr21:9438140-9438338-0
GAAGGTCCTCGGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTTA
+
HI@E?@GGAHACF!HIBGCB??AEBEBBDDHIDHBFGDBGFABE@B?H?HF?DAB@IG??F?IHCCDDIIABFHHHCDFBAFC@BHGGDCGA?AHDBFAE
@>chr21:9438140-9438338-1
GAAGGTCCTCAGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACTTGATTTTTTA
+
GBGBAEF@FB?E?CF?FEBEIIDDCBAC@CGFG?BEF?G@EEGCCIDDFAGEEDDBE?D@@BHFGACFCGDDFHICACDIE?DA?BFEF2DID0?G?BAA
@>chr21:9438140-9438338-2
GAAGGTGCTCAGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACNCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTTA
+
?=E?HH%@AAGIDIAABC@GBADBFCFEE@E?@BE@@GAD@BDGEI@HEHEAHF0HCDBF?I@?AD@D-BHFIICCEDDHIEA@CCGGE??EAAD@EGC?
@>chr21:9438140-9438338-3
GAAGGTCCTCTGCGGGGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGANAAAACCCGCGGCGGCGGTGGCAACAA
+
EHIBDH@GGB@EAFI>BHDCIE@DF@GGIGFDF@B@BGIGHBA?@FIFDHIGFHHAEGCC?B?IIBAGG?DEF9HI?DBH@FDCFFCBFIFHFDHCA6BE
@>chr21:9438140-9438338-4
GAAGGTCCTCTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAAAAA
+
GBBGFEEABBDFGE?I?CDGHF@DGGGIBDIG?IF@@AIFB@FAGIHEAA??BHDCIGGF@AGEC?CIBHDAAHE?E?@IEGG?ICEAC@CIGBEHIBA@
@>chr21:9438140-9438338-5
GAAGGTCCTCTGCGGCGGCGGNGGCCNAAAGCATCGGGGGCAAAAAAACACAAACAGCCGCGGCGGCGGGGGAAAAAACCCGCGGTGGCGTTGGCAAAAA
+
DCBI@EBDC@I?HFA?FEI@I7IBHC7@CCIIG@IFHH?EIHGH??DCCAE?AA8AFFICAB@BEFFEAAFEEHCAI@DFGI?IG8E??I>CBIEHI?FE
@>chr21:9438140-9438338-0
CCGGCGTACGGCTTTTTACTCCCACTGCCACGACTTTTTGCGNCCACCGTCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTTAC
+
4EBE?HEADH@C@BGFGH@GBGI?CEI?H?EI@E?C?HDAIB)@DEBE?3@DGBI?DH@H?DAFIAFFFCICAB?CA@DEE@BF?EEACI@A@AGDHGBH
@>chr21:9438140-9438338-1
GCGGCGTACGGCTTTTTTCTCCCGCTGCCACGATTTTTTGCGCCCACCGCCACGCCTTGTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTTAC
+
DAGAIDGECFGIIIDHF0GDAGF9HIHFBEHAE'G@H@BCEHGHBIB@HECFCCCEF?/?GHDAEIEGG?EFGGCEGFHBGFEFDIBDBGDD@BBGEB@I
@>chr21:9438140-9438338-2
GCGGCGTACGGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGGACGCCAAGGCTTTTGCCGACGTGATTTTTTAC
+
ID?FI?@@CDAC@?D@I?DGF@GGEACE?FCHEHBF@CAEBDIEDBIA??@DCC@FIHACBFCIFD@IHEEHGFG??B?GDGEDDGCAE@FEEIFDHFID
@>chr21:9438140-9438338-3
GCGGCGTACTGCGGCGGCGGGGGCCGAAAGGATCGGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGAGAAAACCCGCGGCGGCGGTGGCAAAAAG
+
BI?CFAFIGCBBH@IBFHDAB@I@BB@HA?>A?BIG@B?G?DB@FH@?BC@BCGHBFFIIHI?EDEBBEBFD,BA@CE@CBHFCEAHHFFEIC@?EGG?H
@>chr21:9438140-9438338-4
GCGGCGTACTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAAGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAAAAAG
+
FFEIHDIFD@BIGBGCHCCFBICDBHEFFIE@IGC@A@A@F?I?AGFG@HDCDIGGFDEBCEDGBFDGDBCB?BDAHG@BGFHAHDFHACAE@EAF?D@F
@>chr21:9438140-9438338-5
GCGGCGTACTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACANAAAAAGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAAAAAG
+
FEHGBDEI?C@DEBEG?HBFA@HBE@G@A@FEIDFEAFIDHIBF?AID?&FCI?FAAAIBCBAB@FIBGEBBACGCIEIIFGF@DCADHI?EADGIBC?@
@>chr21:9438140-9438338-0
TCAGACGGTAATCGGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCAGCGCCACGCCTTTTTGCCCTGGACNCCAAGGCTTTTGCCGACGTGATTTT
+
DFHDDAB?EHC@HACCADICFBEDAIDDFBGDG@ECDFBBG@?FGCFEDH&A?E??HCFHCCBFIH?GIAEHBI,HI?CDC@CGD?I@?AIH@AFBEIDD
@>chr21:9438140-9438338-1
TCAGACGGTAATCAGCTTTTGACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTGTTTGCCCTGGACGCGAAGGCTTTTGCCGACGTGATTTT
+
@A@@?HDBB@A@ADADDEC@!AGFGCHFEBG@?HCHDF@FG@HDC?EGDAHGBIFH@ED??;@DHBHFECHAAB@@)DHE@IFE@FE?AIIEA@EDI@DE
@>chr21:9438140-9438338-2
TCAGACGGTAATCAGCTTTTTACTCCCACTGCCACGACTTTTTGCGCCCACCGCCACGCCTTTTTGCCCTGNACGCCAAGGCTTTTGCCGACGTGATTTT
+
D?DICIED@AEGIBEDDAAFH@AFFIAFH?CB?EACGCIC@GC@BD?E@IDADBIHEGEIFHHA?C??EGD-I?F?DE?CCG@I?GFBGG?GEEII?AD@
@>chr21:9438140-9438338-3
TCAGACGGTAATCTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAAACCGCGGCGGCGGGGGAAAAAACCCGCGGCNGCGGTGGCAA
+
GE@ICHDA@?GF@?DEGGBDC?IFGFEECFFAHAF6A@@HDFHGCHBICB@FIC??EHA8DH@DHEC@CI@AEDD@FAEGAIHCHG?EA,HICGDC@@A?
@>chr21:9438140-9438338-4
TCAGACGGTAATCTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAAAGCCGCGGTGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAA
+
A???C?DH@?BF@AI@HBACI?FIGIBHBG@IEHDAAG@HBFGGD@ICGIHBICEFI?BAFCBEGD7GDFH?@H?IE@EFGHA?GBEH@AH@CBC@BIFB
@>chr21:9438140-9438338-5
TCAGACGGTAATCTGCGGCGGCGGGGGCCGAAAGCATCGGGGGCAAAAAAACACAAAACGCCGCGGCGGCGGGGGAAAAAACCCGCGGCGGCGGTGGCAA
+
BDDI@D?GD@@@EIFBCDIE?CD?ECAB@CDFED?AIEHFBI@ECGEDG@FDCECBD?9HIBEA?DBAIGFFHCGEB@GA?AAIDCDGBGGCCEFFIIIG
@>chr21:9438699-9438824-0
ACCACTATGTCAGCTTTTTCCCCCACCGCCGCGGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTC
+
?CBE@?BHBHBDAD?DH?CECIBE?AF?DFGAEHHF@CD@?BAGHBDHAFAFD?@B@EGCGEFEHD@IBAG@F?ICGABB?@AE@FECAAD@GE@D?DFD
@>chr21:9438699-9438824-1
ACCACTATGTCAGCTTTTTCCCCCACCGCCGCGGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCNCGTTTTTGTC
+
EACFGIEDGE?HGIACG?ACAFIF@DBG?CHEGAGEF@IHC@?DIBFAHBFDABFH?DGGIFDFAHI@GBGAFEHIF?EHGEEC@?A?C$B@B-ACGBH@
@>chr21:9438699-9438824-2
ACCACTATGTCAGTTTTTTCCCCCACCGCCGCGGGTTTTGCGGACGCGGATTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTC
+
IFI@@D@?@B@D@.D?FDI?IIGAFBEFA?@BGIBCIIEHDB@@?GEID.?GDICH?G?EGC@HCBGED@AF?GEBDHC?CCADG?DGDFD@GH@D?@FG
@>chr21:9438699-9438824-3
ACCACTATGTCTNCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAACAAGCCGCGGCGGGGGGCGCAAAAAGCCGC
+
CBCDA@DHIGH@:HDIIFCFA@?BCFBA@I@C@CDAGE@BCGFEIDH@DCH?GCGCHC?GI@FGCEFG@C%FIAI@IECD?H?:GCGIBEGCIEDG?D@@
@>chr21:9438699-9438824-4
ACCACTATGTCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCGC
+
FBCFEI@HI@CIG@@HCI?GG?IE@@BHBB@IB?IEFC@GCBFHAAICF@F@DA@@I?BBEID@DDDA?IDH@CGC?G?I?ABEGEAHGA?D@B?@CDEC
@>chr21:9438699-9438824-5
ACCACTATGTCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGNGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCGC
+
?AHAIEIDC?)BBHECIICI?G9CIBCB?ICBIEHGDDH@F@DDGIIHBDAHHBGCC?F@?ACD@:BFC?FAFGD%AGFEB?IDDFFAAI?@GG?@EE@A
@>chr21:9438699-9438824-0
CTCATACCACGCAGCTTTTTCCCCCACCGCCGCTGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGT
+
EBC?CFD@ADI?DIA@HF$?EI?GEAB?@DA@EHBH?HD?HHIA@F@?BEGADHIH??H@HAGEBBC@C@?AHGIGB@E?@IFICEAHEDICHG@??AHF
@>chr21:9438699-9438824-1
CTCATACCACGCAGCTTTTTCCCCCACCGCCGCTGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTNTGCTCCGTGCCGCTCGTTTTTGT
+
0EEA@A@BGE?BG?CCHEB@HHGGDB?@CDFC?B@FAGF?B@@@?GDAIDEIBB@EBHECC?EIIHA.EH?EC@CE'BEGEFDDGCCAGBGIBA@AGIBH
@>chr21:9438699-9438824-2
CTCATACCACGCAGCTTTTTCCCTCACCGCCGCTGGTTTTGCTGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGT
+
?CG?DAFDG@?F?EGACCCB@D@5@HI?CCDBBCBF?GGAEE'IB@D@EB@ADAHABIA@FG?ECFGABEAGBHFI@CGE@GBEFG@FBDHCB?FGC?BB
@>chr21:9438699-9438824-3
CTCATACCACGCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCG
+
FFA@GDIEH@AAFFFCGCBGABDIEFGBHAB@HHHFEBAGAC?HA?HIIE@HAHH@AFF@A?BFG?H@FIHEIA@IIDDBEAAFBAHCF@DBB?GAAF@?
@>chr21:9438699-9438824-4
CTCATACCACGCTGCGGCGGCGGGGTCNAAAAGCCGCGGCGGCGGGGACNAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCG
+
IGBA?CFHDDG?@AECCBBBIDDEDIB,DHEFGGFECA@H?AG?CBE?I%CCH@C@I:EEBHHGIFHH@GDGEFEHAEIHFDEBA@FDEDEEFIBCEABD
@>chr21:9438699-9438824-5
GTCATACCACGCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAATGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCG
+
4D?@B@FIFIEDGII?AF?DFI?IDFHADCH@C?G?EGDFFFBHGIFCABDCIB4@?F@IDF@GD@ABI?FBICCHFHACBH?IEGCI?A?AD?HH?EDH
@>chr21:9438699-9438824-0
GAAGGTCCTCAGCTTTTTCCCCCACCGCCGCTGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTCC
+
IBEFHBBFDBEGFCB?BADBGHEEGF@DH@AEGDDHFI@G?BBA??ACF@EDCCE?FIGHE@D>?B@AF?BEI@BHGI?FCF?CEGDAAD@DE?AB?H@F
@>chr21:9438699-9438824-1
GAAGGTCCTCAGCTTTTTCCCCCACCTCCGCGGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTCC
+
HIFB?DBBFAG?CGAIGAGBI?GE@B6@A@BEFGIGDFFH@CB@FBD?CAGGAGE??DIHHEDEAGC@EFFHAFHCAE?DF@FHB?AFIABBGADHEFFF
@>chr21:9438699-9438824-2
GAAGGTCCTCAGCTTTTTCCCCCACCGCCGCGGGTTTTGCGGGCGNGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTCC
+
GHH@CFFDAIEH?ADGHADB?@FDCE??HDFCIE@@IFEBBF/C@.ABGDBFEEFEDFI?A?DC?DC@@FDAI?CCIBA?FABGFGCEHIHHABF@AH@H
@>chr21:9438699-9438824-3
GAAGGTCCTCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCGCG
+
BDC@AIEEFECEEGGCDDGGIFFFHBGIEGEHIDBAII@BFGFFIHHDDBDAGGAGFDCBDGEHEG???BC@HIC?@@B@EEF@HABAGFCHC@IIBD@A
@>chr21:9438699-9438824-4
GAAGGTCCTCTGCGGCGGCGGGGTCAAAAAGCCGCCGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCGCG
+
I?IDFIAI@HFHDG@GHHFHCA@FCHFHAHDBEC?1CGIFGEAECE?E@IHGGGCGABFACIHE@DH?FEBA?FIA?GFCFH?DAFFIDHFHFFDFAE?A
@>chr21:9438699-9438824-5
GAAGGTCCTCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGNGCGCAAAAAGCCGCG
+
DCBCE@@BDHII?IDIG?CDB@?DIFHDA?FIBFCCFIAIFDH@DAG@ICIA?CEBI@FAEGEI?@GFCEBDAC?GAFDD@IGB&BEH@?B?AHBF?HCB
@>chr21:9438699-9438824-0
GCGGCGTACAGCTTTTTCCCCCACCGCCGCTGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTCNC
+
CB@IBA7CHDD?F@DFIAEHHGHAH?DDIAEICCFCGG@IBFGEAHI?I?AHFGGABA@?BDF@A@FIFHGHGD?@@FACGCHHGCCIDGHF??B@A?+@
@>chr21:9438699-9438824-1
GCGGCGTACAGCTTTTTCCCCCACCGCCGCTGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTCCC
+
AI@B?C@@GA@E@#@DCGE?G?H@?BFFBFCFDCH?BBBB@?I@BEE?FGCEGEBGHICEDGDEDHGEHAGCDCDA@@I@EEFHDCC?HBE@DC@I?@IE
@>chr21:9438699-9438824-2
GCGGCGTACAGCTTTTTCCCCCACCGCCGCTGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTGTCCC
+
GDCC?FAEDDFHBGIBFFBIHFD@CB?C@FFD?C@IF@B?HDFHHB?H@GGIHBBH@EDB?@AIIBIDA@?@EG@DFA?#A?BDHCHABCAAFE??DCHF
@>chr21:9438699-9438824-3
GCGGCGTACTGCGGCNGCGGGGTAAAAAAGCCGCGGCGGCGGGGACAACAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCGCGT
+
G??I?C@EDDDDE??=I@GEHCA!FHCCGAADCHGC?CDFEDECFCBC+F@DGDABAGCICCHE?E?F@?EED@FE@G@IDDCIHDAAE?@FFAIEIHAI
@>chr21:9438699-9438824-4
GCGGCATACTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCCGTGT
+
?G@FE8@@?DAA?FH?FGHGACDIE?FF?DDFEH?IFEAHHHCI@D@HHBI@EACDE@@ACBB?HFIIGIEAEEGFII@HCBII?EEAADCEBDH?B(FB
@>chr21:9438699-9438824-5
GCGGCGTACTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGCACAAAAACGAGCGGCACGGAGCAAAGAGCCGCGGCGGTGGGCGCANAAAGCCGCGT
+
H#BB@ACFA?D?@FIEGFA?AIFIGD?G@BA@DHDFFE?HF?B$A@AD@B??BGEACBI@CBAFAC@GG*HCECCFFAIGE?FCBCCAF!?EGDFFEGB@
@>chr21:9438699-9438824-0
TCAGACGGTAATCAGCTTTTTCCCCCACCGCCGCTGGTTTTGNGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTG
+
@AGBDHBAEICDHA?DCHGGAFHCBDADBCH@DDFIH?FHHB)AA?B@HHIC@IHEFB?@FDGD@CDDD@CF??EIIBADCGDA@C?BI?FBIHIHCBHC
@>chr21:9438699-9438824-1
TCAGACGGTAATCAGCTTTTTCCCCCACCGCCGCGGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCCGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTG
+
C?IC@C?B@AGE?DFFADAGIHICIEH?GHD?FH@DCGEGDEAD?BHGHCDEEIIH?HAFEFFGAE?F?FBHAG@I?BDBABI7HAGG?AGB@CGAAGHD
@>chr21:9438699-9438824-2
TCAGACGGTAATCAGCTTTTTCCCCCACCGCCGCGGGTTTTGCGGACGCGGCTTTTTGCGCCCACCGCNGCGGCTTTTTGCTCCGTGCCGCTCGTTTTTG
+
FFEACIDG@ECGIHDBEAC?D@ICI?DEIHGHABIFCAH@GDFIAFDDD@BFFGHHFICFCABF@D@G#?I??A?ABACFIHDHI?DC?HG?BFBFAFFD
@>chr21:9438699-9438824-3
TCAGACGGTAATCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACNGAGCAAAAAGCCGCGGCGGTGTGCGCAAAAAGCC
+
?HFEHIHED@CBBEBCGBH?*HABHD?FFIIIBFFD?@BB@EADIH?GA?CC?FDE@DF@HE@CH3@IGDFC?GCIFEACAAEGH@G'CBFGGH@DADAA
@>chr21:9438699-9438824-4
TCAGACGGTAATCTGCGGCGGCGGGGTCAAAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGTTGGGCGCAAAAAGCC
+
CFB?ECBHEA?DBD?CCHDI@BDBC@H?HAC@EEGC#GCEAB@A@?FGFGG?E@HGIAE@HAEFDAAF@HAG?HAGEIAADI?C&IC?HDCBDFGADE@A
@>chr21:9438699-9438824-5
TCAGACGGTAATCTGCGGCGGCGGGGTCANAAAGCCGCGGCGGCGGGGACAAAAACGAGCGGCACGGAGCAAAAAGCCGCGGCGGTGGGCGCAAAAAGCC
+
?F?FI?@DGHEAEC@EACGFDAFAIHI?E!@D?I?FCH?GE@A?CBDBEB@HIFGIHDGFF@@BIIFHIIFIBEI@FEI@@E??DHGFBIIA??IHCCHE
@>chr21:9439135-9439219-0
ACCACTATGTCTGCTTTTTGCTCCTGCCACCGCGNCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATCG
+
IABH?@EAIBF?HGECB?@@CEGGGCHD?EAFI@.EABGA@GBFEFBCGIAEBFIB@AEGFGBCECCEGC?@?IGCIDIHFA?IAGAEA?FBFGD?HADC
@>chr21:9439135-9439219-1
ACCACTATGTCTGCTTTTTGCNCCTGCCACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATCG
+
HCGADC?FCFE@I?GGEEHG@%DIDEFAEFDHE@CCBAECIB?BEAHBIGACFFIAHH??F@?@@EAA?DDFFB@H@BF?BCFADCDBIHHD&G?I?H@F
@>chr21:9439135-9439219-2
ACCACTATGTCTGCTTTTTGCTCCTGCCACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATCG
+
@IHD@FFBFIGDFBHGDBIIAFDB@HBA?AI??A?IGEFAIHEDFEAHHD?DCIHBHAIC?EHBAF@DBHDDG?DIHAB??EGHECHGBBHG@GAAB?AC
@>chr21:9439135-9439219-3
ACCACTATGTCAGCACCAGGGGAAAAATCATCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGGCAGGACCAAAAAGCAGAGATCG
+
ECIFD<FGFBA@GFBE@F??BFH?AIAIF&CHGCFHBI@FE@GG$CHCEHBCFBGEAF?@??D?IFIAIGHB@AA???CEEAB#BBAGCCG?HHFGG@FA
@>chr21:9439135-9439219-4
ACCACTATGTCAGCACCAGGGGAAAANTCCTCCGCGGTGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGGCAGGAGCAAAAAGCAGAGATCG
+
?@HF@HBEIHIDEFFIB?FFDAAFAE"IEFCCEDCHB%EGAI?FID?D?E?B?HAFCI?C@?G@DD@IGCGCEEEDBA@AIBBG?IC?E@?BBG?@?A?F
@>chr21:9439135-9439219-5
ACCACTATGTCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGGCAGGAGCAAAAAGCAGAGATCG
+
CFEB@CBE@@A?DCFCGEGF@ABC@BB@C@?DCB@IGBG?FGFC@G?DGBCAFDB@GCHCEDAGCCDAAHBCC@?G@FI?GHCEGDAAFE?EEFIDACFH
@>chr21:9439135-9439219-0
CTCATACCACGCTGCTTTTTGCTCCTGGCACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATC
+
GCAC?DH@GHFIFBCEEDE@EIHFB@@=GIGHCAGEAE@DAGC@ECHGFFBB?BG@CCAABC@EI@IBECHFAEAHGBCEGDGIIIHACCDEEECHDFG?
@>chr21:9439135-9439219-1
CTCATACCACGCTGCTTTTTGCTCCTGCCACCGCTGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTACCCTGGTGCTGAGATC
+
DIHFBG?GDHH?ECC@IGDFI?FGDBBGD@GGDF7FEFE@HB?@?E@DA@BFGGCD?B?E@B?FDCHEBCHEFC??FG?@BDC!?CI@BBHD@ACC@CEH
@>chr21:9439135-9439219-2
CTCATACCACGCTGCTTTTTGCTCCTGCCACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATC
+
BBHBF??AABA?BCBIBF@E?DGG@A?@BHIHEADAHEIGEEHECGACAHBEAG@C@BEFA@AG?BGBD@GGCDDGFAF@CEHEDEBHCIEICCE@GDH@
@>chr21:9439135-9439219-3
CTCATACCACGCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGGCAGGAGCAAAAAGCAGAGATC
+
D@@EHFEDCG@F@CHB?DBAGADFBF@@@H?HEGDGE?AFIHFFH@DBHGFGFCEI@@@?IIA?AD?BI?AFEGHAB??DHCAD@CCGGAHC@H@?GDCA
@>chr21:9439135-9439219-4
CTCATACCACGCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGTCAGGAGCAAAAAGCAGAGATC
+
@?EEEAEHIE?CAEB??GA@HFDEDFAGECGIGC@@ABCAHIBGBCAI@IGDDDDHGBDDHC?FH??H@DHHEDDCA@HIGGIG@DA?EAG@?@@GD@GA
@>chr21:9439135-9439219-5
CTCATACCACGCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGTCAGGAGCAAAAAGCAGAGATC
+
FFGEIBFBEBACFFDI@ADFA?DB@BIFHGIDCHGEEAHGH?HFE?BBIGFD?DAGAI?@CDC?AHAA@BGA?H@I@HB@?HF?IGHCACCACD@HGBI?
@>chr21:9439135-9439219-0
GAAGGTCCTCTGCTTTTTGCTCCTGACACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATCGG
+
BGFADBD@?CCB??EHCGHAEE?FAFGIDC?DAF@BHEHI@C??CGFICECAE@GE@CGA?A@AAEE?CDIGBBCAI?IAA@BGIAAC??IBHACDIHGC
@>chr21:9439135-9439219-1
GAAGGTCCTCTGCTTTTTGCTCCTGACACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCNGCGGAGGATTTTTCCCCTGGTGCTGAGATCGG
+
B@HBFCAGDAHBCFF?EDGIDBAI@BB@H@G@?BEICAGEHAA@HHC?II?ACIABG@E?EHGCHCF:DGAFDB?HGGFIIED@A?GIAHAHE@DCIAIA
@>chr21:9439135-9439219-2
GAAGGTCCTCTGCTTTTTGCTCCTGACACCGCGGCTTTTTGCCCCCGCCGCGGATCTTTACCCCCGCCGCGGAGGATTTTTCCCTTGGTGCTGAGATCGG
+
A@F?BGIC?B@@GFAG@GGFE@DEGCGECIHCI?IEDH?IFE?IEHIEDFBIADA.G@EIG?BB@BBDEDDCGCHIAAHGBABC(AAFEEAIBI@??EFH
@>chr21:9439135-9439219-3
GAAGGTCCTCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGTCAGGAGCAAAAAGCAGAGATCGG
+
?GB?IIII?BAIHEIC@D@DHBHCH?BAE?@HIIG?IBAAG??FHFDH?FFH@G?E?CBD?FBEAHFDCA?FC?G@B@B?@B?DFHCCGB@IDA@ACFDI
@>chr21:9439135-9439219-4
GAAGGTCCTCAGCACCTGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGCGTCAGGAGCAAAAAGCAGAGATCGG
+
HIH@HCAAFEDIG?HH2EGICHAECDGHAHHIF?I@?EDGADF@DHCECCBBE@FAG?F?CG@D@IDGGGFCIC4@IIG@BBAAHBDHA?EAB@@?AAAB
@>chr21:9439135-9439219-5
GAAGGTCCTCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGTCAGGAGCAAAAAGCAGAGATCGG
+
IA@FEGDG?CEA??FIICHFFFCE?DCIH?DHCFHIACGD@CCCEAFEEE@H?BEFEF?FABCDBGCFEHF@I?FFCH??CBFFDHGDDFFABGHFCBEH
@>chr21:9439135-9439219-0
GCGGCGTACTGCTTTTTGCTCCTGACACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGANGATTTTTCCCCTGGTGCTGAGATCGGA
+
HDC@DBEAFIDAEC@E??E?GGG@CHACCFCDBBECIDHDFA?D@AHBBFHEAFADAIEACABB?GAAFA@F>HIA?I?FD?CCFE??C?FHGAG?D@HC
@>chr21:9439135-9439219-1
GGGGCGTACTGCTTTTTGCTCCTGCCACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATCGGA
+
B+DFD%?C?FDHFBAHD?@HAAI@DDCDGB@BDFAC@DDFH?AAFAHBB@IGAI@AIBBIAIEFEAGDA@EADDADFAFDBBFAAAB?AEFDAD?DDIII
@>chr21:9439135-9439219-2
GCGGCGTACTGCTTTTTGCTCCTGCCACCGCGGGTTTTTGCCCCCGACGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGATCGGA
+
IGGCFDEE@FFBB@@FAG@DCHA@FHBIGEIG@&EGB?F@D@CHAG*EGFIIEGFCGFDHIA@CAFEBECHBDBHIIDCHBDEDGBBGBIFEEAF?IBCH
@>chr21:9439135-9439219-3
GCGGCGTACAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGGCAGGAGCAAAAAGCAGAGATCGGA
+
B@?@CIIGHECD?CDB@FBCBEGCDFIHF@IF?EID?EG@@@BBIFI?CHADGI@EEE@@CC@FC??<EDFAB@@DG?A@GAFBE?DEIIACCDEEABGE
@>chr21:9439135-9439219-4
GCGGCGTACAGCACCAGGTGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAANAAGCCGCGGTGTCAGGAGCAAAAAGCAGAGAGCGGA
+
@BAFICE?GFDIGIE@HA)G?@@BH?HGGIE?IFADFAAEDBE@?GHDB@EBICCBGDCFHCD<D?GAG@G?GFGFIEECGBCGI???IHEIGBC;H)G?
@>chr21:9439135-9439219-5
GCGGCGTACAGCACCAGGGGAAAAATCGTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGTCAGGAGCAAAAAGCAGAGATCGGA
+
CAHBHIFEB?IGEB@AF?@IH0IHAHH0BDFHDEECDD?CEG@BDCHGDHBBC?ECEFCFGIGABFIBFBIFC@BD?BGAIG?@AFDCFIFG@IF@EDD?
@>chr21:9439135-9439219-0
TCAGACGGTAATCTGCTGTTTGCTCCTGCCACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGAT
+
GFHE??I@EEHEHIEGI!?BECAE?@?CCGI??@FFG@DGAE@CCHH@E?EDIBF?DG?BIHECFCE?BC@GCAEAHIEGAEHDAI?H@FAHCGBAE?GG
@>chr21:9439135-9439219-1
TCAGACGGTAATCTGCTTTTTGCTCCTGCCACCGCGGCTTTTTNCCCCCGCCGCGGATTCTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGAT
+
?A@A?HG?F@CEGGFBHHAB?EEHHIECHEACD?BHGCDBHCD6FEFHEEC+DGFBF@H.IBIGCFCDBHBHECEIB?I?BDGB?@G?DGI?@II@IIHH
@>chr21:9439135-9439219-2
TCAGACGGTAATCTGCTTTTTTCTCCTGCCACCGCGGCTTTTTGCCCCCGCCGCGGATTTTTACCCCCGCCGCGGAGGATTTTTCCCCTGGTGCTGAGAT
+
EBEGICAFFGBDGED@BGI@G3BDI?CEGGBB?CDACBABHD?AHFEIGFG?AD?CFEHIIA@HGGDBA@?B@E@BEDFEFD=CCFF?HDIDB@DBIA@H
@>chr21:9439135-9439219-3
TCAGACGGTAATCAGCACCAGGGGGAAAATCCTCCGCCGCGGGGGTAAAAATGCGCGGCGGTGGCAAAAAGCCGCGGTGGCAGGAGCAAAAAGCAGAGAT
+
AB@HHDHGBCHDAIHFGG@I?FHF0DC@EBBDGF?C@<BE@IBEGAHIAHID8AB@?CI?D&A@HD&BBECGECE@IGAEECC?EFDEFICDGFCHHI@A
@>chr21:9439135-9439219-4
TCAGACGGTAATCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTGGCAGGAGCAAAANGCAGATAT
+
FC:EFICBDC?GAH@C@EDHGDADDIAHHFGB@FGE@FCIII@DC?EDH@CHFCHHGAEBICGAEAGGABIDGEICIGHFHFIF?IABFIF$FD@DG;HC
@>chr21:9439135-9439219-5
TCAGACGGTAATCAGCACCAGGGGAAAAATCCTCCGCGGCGGGGGTAAAAATCCGCGGCGGGGGCAAAAAGCCGCGGTNGCAGGAGCAAAAAGCAGAGAT
+
AG@DE@ADIIBIAFDDFHEGHEICAD?DHIC?HAE?FA?H?GIFF?HBAGHFBCHBHBIFIFCD@C@ADHFFCFA?AD"@DFG?AH?D?GIC@F@ADCFB
@>chr21:9439279-9439392-0
ACCACTATGTCAGCGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTCTGCCTAGGCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCTCT
+
D@AFIAGGIFG@GHCAGCBEF?@GD?HIB?GE@GAEIFFHD@E@CDAEBDF@FAFEDG2H?CEDECFEHIAAIC@CFB@DAF@@C@BAB?A@FCDEAHHC
@>chr21:9439279-9439392-1
ACCACTATGTCAGCGCCGAGGGGCGCTACTGGTCCAGCTCTCGTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCTCT
+
II?CH?@EBG@FI???CHEBCICAHCH'??FI???HIAIB?D,?CFAGBG@FF@EEG?CHGCF@EGDIDA?BCAD@????F?AGD?GEHEDAAADAAHCB
@>chr21:9439279-9439392-2
ACCACTATGTCAGCGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTTTGGCTAGGCGCCGGCGCCCCGAGCTCCCTGCCTCGGCCTCT
+
?CDGDAH?D?GH?E@GCHA@@IA?CB)@A?CH@?GGBH@IFEDBDEFBIB?ECIGFFHEBA.IEB?FEE?E@HFFDI@DC"DEGIADGAEEIBDFECDDA
@>chr21:9439279-9439392-3
ACCACTATGTCAGCGCCGCTCTATGCAGGCCNCAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCTGG
+
FGFIIBIIAFBDG?ICDFE??EDCFHGIDCI+??I?IEDE?EEFD@BHAIBFCGCB?FD@BBDAGE@A?B?EBDC@FDAC?AA??BFCBHIACDFGFAID
@>chr21:9439279-9439392-4
ACCACTATGTCAGCGCCGCTCTATGCAGGCCACAGAGGCTGAGGCAGGGAGCCCGGGGCGCCGGCGTCTAGGCGAAGAACCCCCGAGCCAGGAGAGCTGG
+
GDD@GGGHCCGGFGBAGDBGBBIF3CHCDBHHDGBAH?H-H?EGDCDHIDAF@@A@?EACC?@?IG/??H?EH'C@E@IICCIBEAFACBBFGCGFFIA?
@>chr21:9439279-9439392-5
ACCACTATGTCAGCGCCGCTCTATGCAGGCCACAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCTGG
+
GBDIA@CH@AGFHIHCBE?DE?F@GCCFGGHA?AFBHFHAG?G@G?EEA!BEG@@DHGE@AFDH@DF@BGEHG?GA@EEIIBDIEFG7GACH@EI??BGD
@>chr21:9439279-9439392-0
CTCATACCACGCAACGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTTGGCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCTC
+
IE@IA?BAEHD@B5HIAD?BGE?III??DIDCFCCACBEED@GHAADICDBIIDACCBAHHBFEF<A@?HE@GCDFFCIFAIHDHH?@DBGHFHFACI@C
@>chr21:9439279-9439392-1
CTCATACCACGCAGCGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGNGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCTC
+
AEIHA@GDAHHCEFGEAAD?E@D@DCFBCD@DCECCBEI?CIAHB?DBAGBA/B@D?@I?I@HB@?BBADFFDHE?HI@@DCAH@EFCGCGGAIBGGFHE
@>chr21:9439279-9439392-2
CTCATACCACGCAACGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCNGGGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCTC
+
HFED@EEGCG@AG$@HB?DBC??GA??F@F@FIIEAB?@FBC@?GDDGCD8AADA@FE@AAI?@FEFHFHGDCCIHHDBGGEBECFB?FD@IBFHI??AE
@>chr21:9439279-9439392-3
CTCATACCACGCAGCGCCGCTCTATGCAGGCCACAGAGGCCGANGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCTG
+
EBFFE@I@I@@@ICAEFDEACCFDACECIB@AGGCFF@F@BCA7EEIIHD?FH@@IB@CDFGCFCCDFDD@HIDCC?AI@CCFGHBDB??GACA?HCBGE
@>chr21:9439279-9439392-4
CTCATACTACGCAGCGCCGCTCTATGCAGGCCACAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCATAGGCAAAGAACCCCCGAGCCAGGAGAGCTG
+
CF@EFGF)ECCI?E@F@*A@G??GC?AC?G?CCCID?A@A@BEIGI@ABF@EBDHG?HF??BIEH@G?#EFAG??AHEAI?EDCDHG?CIHF@)FBDEGD
@>chr21:9439279-9439392-5
CTCATACCACGCAGCGCCGCTCTATGCAGGCCACACAGGCCGAGGCAGGGAGGCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCTG
+
ADEBDBECCIGADDIIEI@@IECA?@DEFG@BHEC1AHFDF@HD?BGEFBBG=@IG@??FI?GGAI@BHGE?G?BEHCE@GIHDFCDDI@?EBIG?FHAG
@>chr21:9439279-9439392-0
GAAGGTCCTCAGCGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCCCGGCTCCCTGCCTCGGACTCTG
+
FEAGCFI@ECCB@GCBBABFGF?IB?BGBFIGCDE@GCI?ICD?IB@GIBHAADBG@ABACEH?DEBADFDGGFAF@I(G?A@HGIBIEDB@IH$CAFI?
@>chr21:9439279-9439392-1
GAAGGTCCTCAGCGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCTGGGCTCCCTGCCTGGGCCTCTG
+
?DCI?HGEIDDAGEBDCD?IBDED@HCHHC@?AEFGIBGF?B?HGB@AFDCGD@HH?DEIAC@HBGCCCBAG?FADB%?FE@DEED?DA?E>IIAHFF@C
@>chr21:9439279-9439392-2
GAAGGTCCTCAGCGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCCTGACTCGGCNTCTG
+
EFHFBDCAABAGAIGA@DAHI?GAHEE?BFEG?CIHAD?HFEC?IHAFH@C?AC?CG@@HHB?@AE@@GBDADBCB@BICH@HACHFC*IDCCAE6A?FA
@>chr21:9439279-9439392-3
GAAGGTCTTCAGCGCCGCTCTATGCAGGCCACAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCTGGA
+
EHG?H@C)HDHAAC?BADEGAGHBCD?IGCHF?DAEE@?AACDBADCEB?@BIIIBBIBIEBHG?DHH@CDAF@FE?GEGA?ADBHGAEGBB@EAEEA@?
@>chr21:9439279-9439392-4
GAAGGTCCTCAGCGCCGCTATATGCAGGCCACAGAGACCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCTGGA
+
I@E?HC?D@CADGD@DFFI7ICI??IEACIAAFE?H$FAAE?HAG@@BBH@AGAHI?IH@GI@GIG?EIAD@B?ADEE@AHA@DCHHB?DICGBFGBAHI
@>chr21:9439279-9439392-5
GAAGGTCCTCAGCGCCGCTCTATGCAGGCCACAAAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAAGAGAGCTGGA
+
HEH@BACH=BFIADFCBBI?II?EFDHDBD?FA!EGHADBEHDA@IFFC@BFBAGD?G?@@EADBHA@GEDD@?AACGFDCEFCGHBHH=?DEIDGEEFF
@>chr21:9439279-9439392-0
GCGGCGTACAGCGCCGAGGGGCGCTCCTGGTGCAGCTCTCCTGGCTCGGGGGTTCTTTGCCCAGACGCCGGCGCCCCGGGCTCCCTGCCTCGGCCTCTGT
+
D@FDFFDICD@G@GC?GCHIDHAIEBDDIBDCCCDCCIGFGIAHIADFG@AIGEHBG?IEH-C?$CD?ADDDBIGHDCBE?GEHIIAA@FFHIIDFCCEC
@>chr21:9439279-9439392-1
GCGGCGTACAGCGCCGAGGGGCGCTCCTGGTGCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCCGGCCTCGGCCTCTGT
+
DEDDADHAC@DD@??CIEGADDBCCICA@HCACGGGAHHDFHD@HC?IDEHA@EGBGC?BBDEEEGDB?E@C?FFGA?BEFDI?D"EEC@@IC@HAHEF?
@>chr21:9439279-9439392-2
GCGGCGTAAAGCGCCGAGGGGCGCTCCTGGTGCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCTCTGT
+
EGDFHDBD/A@DHHEBD?H?ED?H?G?B@FG@DFI?CEE?CGHHH@IFGF?@@AHIDG@EDGFGF@E@?IC@EC@HHECE@A@AGF@CEE?AHFG?@A?@
@>chr21:9439279-9439392-3
GCGGCGTACAGCGCCGCTCTATGCAGGCCACAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGTAAAGAACCCCCGAGCCAGGANAGCTGCAC
+
ABI@IABDAGHC?E@BCGH@HAFH@HE?IH@EAIHECG??DCEDAFHC@CABD?@BGHEDDDBADCIIDH-EHCG@@DAEF@HGIIHHG@?2AFFHFHEG
@>chr21:9439279-9439392-4
GCGGCGTACAGCGCCGCTCTATGCAGGCCACAGAGCCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCGCCGAGCCAGGAGAGCTGCAC
+
@FAIFICAEFFCFF?FBAI@HAGAGDDBDA?HADA*F@ACDC?BHCE?HI?HICBBIC?@IF@C?E@BFECG?@F?GDD$BDCIBHABEHHCEDHFHH?C
@>chr21:9439279-9439392-5
GCGGCGTANAGCGCCGCTCTATGCAGGCCAGAGAGGCCGAGGCAGGGAGCCCGGGACGCCGCCGCCTGGGCAAAGAACCCCCGAGCCAGGAGAGCTGCAC
+
?FCEAAEC(G?BE@F?E@EGGCEC@FHA@H'BHFFHIFHCHGADIICEEGB@IDG.ABCCG)B?BFA3IAHHIEFF@FIDI??AFEI?AAHIDIDCFABI
@>chr21:9439279-9439392-0
TCAGACGGTAATCAGCGCCGAGGTGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCNTGCCTCNGNCT
+
D?AEHBGDDFAFGBH??ECEGA@-GAHGGIG?FHIFG@FGCGD@HBIDH@I?FE?A?EDDHCC@CHFBE@@CAF?I?HEC@DI?CFHC5?FGIFH8?)CH
@>chr21:9439279-9439392-1
TCAGACGGTAATCAGCGCCGAGGGGCGCTCCTGGTCCAGCTCTCCTGGCTCGGGGGTTCTTTGCCTGGTCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCT
+
CAFH??EBGD@EHHDE@GDDG@ICG@'GEEGAEA@@CBI?EEFEI@IFB@GDAAIG@CCDGDH@HB.F8CAIGFB@-HFE@GEBIII@FBEBBGF@?EEE
@>chr21:9439279-9439392-2
TCAGACGGTAATCAGCGCCGAGGGGCGGTCCTGGTCCANCTCTCCTGGCTCGGGGGTTCTTTGCCTAGGCGCCGGCGCCCCGGGCTCCCTGCCTCGGCCT
+
CEGF?HECBEADIHHH@@C?HIEFD@C!B?CDCEHAIG"IEDF?@FDAADFHIIEGICAIDB?CAGFI?HGEB?CBBBAHHGCFFCHAAE@@HEEEICBG
@>chr21:9439279-9439392-3
TCAGACGGTAATCAGCGCCGCTCTATGCAGGCCACAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTATGCAAAGAACCCCCGAGCCAGGAGAGCT
+
HACIGD@BDICC@?FFAHCICHHBI?CEFHE?GBE@FBAAIIHIG?GAGB@?BAHEFAD@CBA@HA?IHDGA!EBHEGDIAEF@IAAB@?GIGI?FIBFB
@>chr21:9439279-9439392-4
TCAGACGGTAATCAGCGCCGCTCTATGCAGGCCACAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCT
+
EIGHCAEBAGCHAA@A@DCIBDCHHDGEFCE?A?CFDG?ACII?BCEAHABEFABHGAFBEDD??ABDDBC?DEHAAGIAG?F?GE?@I@G?AHG?IFGG
@>chr21:9439279-9439392-5
TCAGACGGTAATCAGCGCCGCTCTATGCAGGCCACAGAGGCCGAGGCAGGGAGCCCGGGGCGCCGGCGCCTAGGCAAAGAACCCCCGAGCCAGGAGAGCT
+
ACCEDBC@@?EAH@D?GEDBGDFAD?GHB@HG@ABFBHEGG@B@AHIHFI?A?CEIEFIAHBHGEIECDBDCI@GA@GCDIAEEICG?HIBAFHGEGCFG
@>chr21:9439389-9439478-0
ACCACTATGTCTGCGCGCAGAGGCGATGGGAGAGAAGAAGGAGGGTGGTGGAGGGGGTGATGCGGCATTAGCGCAAGGTGGCGCAGGGGCCGCGGGCAGA
+
FDD@BCDHEGBDE@GFFDEB?HGCEDFAAIC@@DIAFC?I@ADIEAC@?DI9AAC?FCFEC@@HCC@GBIF@GD??FCE?@DIH@EA?GCC?HI?F?AII
@>chr21:9439389-9439478-1
ACCACTATGTCTGCGCGCAGAGGCGATGGGAGAGAAGAAGCAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGGAAGGTGGCGCAGGGGCCGCGGGCAGA
+
AHDCIDC??H?GFHFBF@AED@IG@HG?GEGIHDDGB"FF;IC@GEHIEEGDBCIB@DHCCCIHGIFC?GEF@DDIAADIFACGFDB?GBEIFA?DGHIB
@>chr21:9439389-9439478-2
ACCACTATGTCTGCGCGCAGAGGCGATGGGAGAGAAGAAGGAGGGTGGTGNCGGGGGTGATGCGGCATTAGCGGAAGGTGGCGCAGGGGCCGCGGGCAGA
+
IGABEI8DCGBBHGE*EB@ACH?IEIB?@IF@FCHADGHA@AF@G?AFEE9HGACCCF?GGABAB@?EH?HHCAD?CBBGGCDADCGBACIICBEGEHCD
@>chr21:9439389-9439478-3
ACCACTATGTCTGCCCGCGGCCCCTGCGCCACCTTCCGCTAACGCCGCATCACCCCCGCCACCCCCCTCCTTCTTCTCTCCCANCGCCTCTGCGCGCAGA
+
DHEDCDBBBEEEEEEGBHIHGFIBBBCFB?@AEGB@ECBAHE,GBHAH@AAEEHGF?HFG??F4?DBGADGD@HHBADHDBCF"CAHIBAEFC@?HA?AB
@>chr21:9439389-9439478-4
ACCACTATGTCTGCCCGCGGCCCCTGCGCCACCTTGCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAGA
+
DFDDC?F@?@@IHAAHCHGFBF?#FDCIFBADEEDBFE?@HGAFDC?@FFCICG@F?HDDE?F?ABB?IF?@BC?GE?ED@HAFHFAADE?@$FE?HG?F
@>chr21:9439389-9439478-5
ACCACTATGTCTGCCCGCGGCCCCTGCGCCACCTTGNGCTAATGCCGCATCACCCCGGCCACCACCCTCCTTCTTCTNTCCCATCGCCTCTGCGCGCAGA
+
@FGBGFCGDGFFFFAIEHCEBIEGHBEEDID@ADAH5?@F?@BFIEFIEFEEF@EE5AA@CGFB?EDDDHF@IFIIB-H@FDABDABBECDACIIAH?D?
@>chr21:9439389-9439478-0
CTCATACCACGCTGCGCGCAGAANCGATGGGAGAGAAGAAGGAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGGAAAGGGGCGCAGGGGCCGCGGGCAG
+
GHIA?CA@?BFH?@EEBFDCH?02HFD@BIHDFDI@D@??HHIFIHEEDE@EE?IFHHC?CBDBBAB@BG?@ICIGH"@5@@GFFBAFH@FCF?BFHDFI
@>chr21:9439389-9439478-1
CTCATACCACGCTGCGCGCAGAGGCGATGGGAGAGAAGAAGGAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGGAAGGTGGCGAAGGGGCCGCGGGCAG
+
DA?IBFBI?HEBEIEFFI@HFBA?IDGCGBE@FHBFG?FD@IE@.E?EADGHBEAI?A@BBHB@C@AGEFDEBC?BH?GHGGID=ICBCFDGIFIAIHHD
@>chr21:9439389-9439478-2
CTCATTCCACGCTGCGCGCANAGGCGATGGGAGAAAAGCAGGAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGGAAGGTGGCGCAGGGGCCGCGGGCAG
+
IBA@@<BEAHHBA?DCBEBG#GB??CFF?GHDIC+@BH4A@AH@BEH?DCIBB@FBGF%GCIDCGG@D?HICFAB@IBA@AHEAEFFHHGEBFGHHC?GF
@>chr21:9439389-9439478-3
CTCATACCACGCTGCCCGCGGCCCCTGCGCCACCTTCCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAG
+
@H@H?A@EBCE?EACDHB?G??FAG?GGCCHDHB??FH?@IF@EGFHIGEDIEF?IFDAGHHDB$CCCC?GIGHGDFB@HGCEEAB?HFCI?FGFF?CAA
@>chr21:9439389-9439478-4
CTCATACCACGCTGCCCGCGGCCCCTGCGCCACCTTCCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAG
+
GAECECGFG@??B?I@@GBC?GCAC=DAF@?FHFEHBEG@FFI?GBDGFEEDIDAAEFICABA?BHBCB@EADHHBA@CC?G@FGC?AGDDBACFD@CC?
@>chr21:9439389-9439478-5
CTCATACCACGCTGCCCGCGGCCCCTGCGCCACCTTCCGCTAATGCCGCNTCACCCCCCCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAG
+
EEG@G?BEIIAEIHCGG?BF?CAI?ACHFHC?FIDAB?HIHAEHF?EIH>DI?IHAE?6CD@DGGCAAFIH@IC@F?FEDBEGGHH?IIDAEEB@ACFEA
@>chr21:9439389-9439478-0
GAAGGTCCTCTGCGCGCAGAGGCGATGGGAGAGAAGAAGGAGGGTGGTGGCGGGAGTGATGCGGCATGAGCGCAAGGTGGCGCAGGGGCCGCGGGCAGAG
+
DDHGD?AHDABGFHFAHIC&DHAG??@@AIB@H?AACCEBIHEFBHIBI@FHAB"GGAB@?CBDAHD)IGBI@F?DC?@?@GBFHDBEACFCCHHGG?E@
@>chr21:9439389-9439478-1
GAAGGTCCTCTGCGCGCAGAGGCGATGGGAGAGAAGAAGGAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGCAAGGTGGCGCAGGGGCCGCGTGCAGAG
+
IHCDHGD???CBGFHB@GGHEC?G?FIHHGB?@?ECDAGCD?EDGHIBDF?GDB?ECCF??AAEGFIF@AAIGAHAEGEC?C?HCEI@@CHHI(?B@DCA
@>chr21:9439389-9439478-2
GAAGGTCCTCTGTGCGCAGAGGCGATGCGAGTGAAGAAGGAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGCAAGGTGGCGCAGGGGCCGCGGGCAGAG
+
BGC?CEH@CG:D"IG?BE?BHA@(@@B;DFI6DHIFBIFEADHEACCHACIIE@E?ICIA?DFHAAFB@DH@BGDCCIICCICGFGBAFGCHGFCHGDH?
@>chr21:9439389-9439478-3
GAAGGTCCTCTGCCCGCGGCCCCTGCGCCACCTTGCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAGAG
+
IG@HICDCCHAAHCDHHDF?HAB?C?GHBACDBGCEHBCBDG?DAIHBGC?CBFAG?A??ICBBGGA@BDDGCHIC?IBAIDA?GAFIDGDGFCDGIAII
@>chr21:9439389-9439478-4
GAAGGTCCTCTGCCCGCGGCCCCTGCGCCACCTTGCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTGCCATCGCCTCTGCGCGCAGAG
+
BA?DBA?ECHGHBIE@IBHCA@?GGHC@GACA?EA??F@?FDEDIGIGC@AEAEAAGD?EEIG?E?DAG?HHAB?AFA0FHFBCBEB@BGECEIAC?:BG
@>chr21:9439389-9439478-5
GAAGGTCCTCTCCCCGCGGCCCCTGCGCCACCTTGCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAGAG
+
FEIFIDFHH@I$?DCBGHECEC?GBGHHGFAIFDACIEECBGEECGH?ACEIDA@IBF?HCE?CIAHFAEIGIF?CIC?BAB@AHED??BIGH?DFIIEG
@>chr21:9439389-9439478-0
GCGGCGTACTGCGCGCAGANGCGATGNGAGAGAAGAAGGAGGGTGGTGGCGGGGGTGAAGCGGCATTAGCGCAAGGTGGCGCAGGGGCCGCGGACAGAGA
+
DHCHECGEG@@FGGHGGAD'I@FCBA9DD?H?HECF@?CIFGGDEDHACIDFFGGFEH&@H?CEI@FE?HFB?CE?DFGCG?@CIF?BBGECB.CG?BDC
@>chr21:9439389-9439478-1
GCGGCGTACTGCGCGCAGAGGCGATGGGAGAGAAGAAGGAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGCAAGGTGGCGCAGGGGCCGCGGGCAGAGA
+
FHECGBEGAE@AHEDCEB@?HF?I@@@?@IHI@AIFHGFE??C@CGHGGHFHFFAFBFI?FDGC@?BEGBGFG@DFD?BFE@F@A?CE?ED@ABBGH?BB
@>chr21:9439389-9439478-2
GCGGCGTACTGCGCGCAGAGGCGATGGGAGAGAAGANGGAGGGTGGTGGCGGGGGTGATGCGGNATTAGCGCAAGGTGGCGCAGGGGCCGCGGGCAGAGA
+
AEGDEEBGGCH@HDDEDHCFEBAHAE??EDDDIE@F1HC@HIAC?BEG?FIGADFHDEAIGAE<ADIAGEFB?B?GEAACCG@GCF@DG@FACEHAF?GF
@>chr21:9439389-9439478-3
GCGGCGTACTGCCCGCGGCCCCTGCGCCACCTTGCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAGAGA
+
@IHGDE?F?AHECFCBDCECDF@GCEA?CA@1G?FDGBG?F@?IE@DEGAAAE?D;IAIEBHAI@IA?HBDHGEDHAIG@?HHDIDAHEDEBHFGIBDHC
@>chr21:9439389-9439478-4
GCGGCGTACTGCCCGCGGCCCCTGAGCCACCTTGCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCNCAGAGA
+
HDH?@DEGGBIDCAEHEHCEDCHH%FIDDBBHDBE@BBAHHDEHDECAA?GHBG@D@@DGDC,?B@GIGHB@BFHHHFA@@BBAGCGBGIEBF(IBHAG?
@>chr21:9439389-9439478-5
TCGGCGTACTGCCCGCGGCCCCTGCGCCACCTTGCGCTAATGCCGCATCACACCCCCCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCAGAGA
+
+HD@HDIGHBDFC?I?GBHCBDEBD@CADCA@EH@I@ABFB?G?DAD@BH@(EBH,AF@IHF@I@E@GA??DGGC?CGIGDDEIABFIEFD@FG??FDFE
@>chr21:9439389-9439478-0
TCAGACGGTAATCTGCGCGCAGAGGCGATGGGNGAGAAGAAGGNGGGTGGTGGCGGGGGTGATGCGGCATTAGCGCAAGGTGGCGCAGGGGCCGCGGGGA
+
ABHEB?IGDE@IHAF?IIH??FBABHBEA??B(@BICCGE@DI,??BAEIFC?CBB@H@@B?HAACEGCIFBGBGCDA@IEC?BGGHEACFAEAED??0D
@>chr21:9439389-9439478-1
TCAGACGGTAATCTGCGCGCAGAGGCGATGGGAGNGAAGAAGGAGGGTGGTGGCGGGGGTGATGCGGCATTAGCGGAAGGTGGCGCAGGGGCCGCGGGCA
+
H@H?EBIEEGHFFFAGDG@GA@BEEDEBBEABHF4AF@H$@E?BGCAIHADBC?I@D%CBAEDAHG@IAFDAB@?F@CE??GD@?DIIIHBFADHE@D@?
@>chr21:9439389-9439478-2
TCAGACGGTAATCTCCGCGCAGAGTCGATGGGAGAGAAGAAGGAGGGTGGTGGCGGGGGTGATGCGCCATTAGCGGAAGGTGGCGCAGGGGCCGCGGGCA
+
ID0B?DHFDCFAEE9@?@B@@BHD3?EDFI@DDDDHAHCHGAB?EBFECHDD@?CA?CH@?CEHIB7FI@@?EFDBFFCEC@I?H??CHEDGGB@I?FAD
@>chr21:9439389-9439478-3
TCAGACGGTAATCTGCCCGCGGCCACAGCGCCACCTTCCGCTAATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGCCCCTGCGCGCA
+
CIH@CACB@D?@HCG@HGD?CBEC4F$AAGF@A?EAG@BEGAGDHE?HF@G?DAE?CDDFAHBBGAGBFHDCECCC?@@??HIDIBE?BI<II?B?BHI?
@>chr21:9439389-9439478-4
TCAGACGGTAATCTGCCCGCGGCCCCTGCGCCACCTTGCGCTNATGCCGCATCACCCCCGCCACCACCCTCCTTCTTCTCTCCCATCGNCTCTGCGCGCA
+
A??GICC@ACHD?I?BCG?DF@@@@C@?F@EFD?AEHDAGDC9CDBE?IEG@DE@CCEDBGHAFGH@ACHFH?.IDD?E@DGFEFBEA-ICDFE?DAFIG
@>chr21:9439389-9439478-5
TCAGACGGTAATCTGCCCGCGGCCCTTGCGCCACCTTGCGCTAATGCCGCAACACCCCCGGCACCACCCTCCTTCTTCTCTCCCATCGCCTCTGCGCGCA
+
CDGEG@AI@A@GIH?E8E@BGIEFI3E?CDHADCGGBEHBACFAGIBIGD?)D@E?DEF?!FIIBBBCED?A@@BHFBHCDGDCFBE@DAADFIEH@EDF
@>chr21:9441895-9441956-0
ACCACTATGTCAGCCTTTCTGTATCTCATACTGTATTCTGCAATGTACTCCTGTGAAAGANAGTTGTGCTGTGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
AABBDCEAFHBFGIAHBC?A@FCFGDHFADCBBHGHE@AGA;CGGDBG?EIFB?DGHC@I4CI@DGAGI@E$@?@FHBBGFIEG@EGFH@HAAGGGEG?G
@>chr21:9441895-9441956-1
ACCACTATGTCAGCCTTTCTGTATCTCATACTGTATTCTGCAAGGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
D@GFI@BCEBHG?@BBA@@GEEGAFD@EHBBEIIECHACCCCEGBDBBHI@HDFC@D?DB@D?DEB?BDIHH@IC?FECBHAGBE@AIGBA???BGC@CE
@>chr21:9441895-9441956-2
ACCACTATGTCAGCCTTTCTGTATCTCATACTGTATTCTGTAAGGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
HHE@?AFAHFHBDHEFBEEI@?IICCFHFIHCHGAH"DCB2E?H&E@?DBAE?AA@B@B@CFDDIC#@HCHBD?GGCDGHCH@HFGCFBECDCBDEAAD@
@>chr21:9441895-9441956-3
ACCACTATGTCAGCACAACTTTCTTTCACAGGAGTTCCTTGCAGAATACAGTATGAGATACAGATAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
G?A@FHIHFBG?CIC?FGCD?FGIBCADB?FHEAD%?DFECIEEHGHAGAIGAI?HBAFE?BC?,E@??CCC@GCDH@GFGBIDDF?DIB?A?EAHEG@D
@>chr21:9441895-9441956-4
ACCACTATGTCAGCACAACTTTCTTTCACAGGAGTACATTGCAGAATGCAGTATGAGATACAGAAAGGCTGAGATCGGAAGAGCGAAACAAAAAAAAAAA
+
BE@CC?BHB@HFECC@@FB?ICABBBEC@C5IGCABCEAGCFHCBBI,GGFHEBAHEAFBGDCDDCH@IAICEE@EIDHCI?AHBCIH"@DBCDBAG@GH
@>chr21:9441895-9441956-5
ACCACTATGTCAGCACAACTTTCTTTCACAGNAGTACATTGCAGAATACAGTATGAGATACANAAAGGCTGAGATCGGAAGAGCGAAAAAACAAAAAAAA
+
C@DE@EDI@AEBCE@GFIEDDFG?@CCCE?E>?D?DEDAAG@GBDBE@BBAAHCHCIEEF?G1CHA?DDHGHD@BAFE@CEDHFG?HBDID"HC?@DGBA
@>chr21:9441895-9441956-0
CTCATACCACGCAGCCTTTCTGTATCGCATACTGTATTCGGCAATGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGANCGAAAAAAAAAAAAAA
+
HBAFGD?GBCD?DIBBHHEGCIDDFA5D@IHHFC?BABE9EHIIFCDFC@E@??EADGAH@IA?A?EBCACI@DIACF?CDFI:BACE?EHDBICF?FCE
@>chr21:9441895-9441956-1
CTCATACCACGCAGCCTTTCTGTATCTCTTACTGTATTCTCCAATGTACTCCNGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
IH?H@H?@D@H?HEIDHCHFH?BAFAD?-I?IGHC@?EF@$ABC?GHFGAEB6FDHHHAG@I@DDFEFIBFGHBEHD?@BEHGBGEDACBBCAAEAHGBF
@>chr21:9441895-9441956-2
CTCATACCACGCAGCCTTTCTGTATCTCATACTGTATTCTGCAATGTACTCNTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
?HEI@FCE@EGFIFDFAIAIBGDGFGDGAHEDIIHH@GGCEBDIBIIIGB?-IEGI??IHIA?IDGHCIHH@ICB?@BI?FDHFCDCHFHCAAA@?C?FF
@>chr21:9441895-9441956-3
CTCATACCATGCAGCACAACTTTCTTTCACAGGAGTACATTACAGAATACAGTATTAGATACAGAAAGGCTGAGATCGGAAGAGCCAAAAAAAAAAAAAA
+
FCDFIEDBD+EFIDB?A?DHF3@I?CACC@FCIICEAEEDD!@AHIEDG@BBHF@,FI?HIDIB??CDI@BC@ECEFBAFF?DGA'E@BGF@DFACBBAE
@>chr21:9441895-9441956-4
CTCATACCACGCAGCACAACTTTCTTTCACAGGAGTACATTGCAGAATACANTATGAGATACAGAAAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
IFF@EB@GGC@AHBG@IFE@?HIAHCFFDDIBBDFEACG??C?FEF@IDGG12@AHB?HAIH@??@BGIEHACAE?IC?ICG?DICEE@GAHCABDBFEB
@>chr21:9441895-9441956-5
CTCATACCACGCAGCACAACTTTCTTTCACAGGAGTACATTGCAGTATACAGTATGAGATACAGAAAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
HBD@@FGAHBEBFFFFDHDDHFBEC?B@AI?BBADBFAHDACECE'HCDBFDFEACHEIAEGEBBCGIAHI@H@@AFBECBDDGBGIB@EEBE?CFGAA?
@>chr21:9441895-9441956-0
GAAGGTCCTCAGCCTTTCTGTATCTCATACTGTATTCTGCAAGGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
D?FACHHIIIHDB@CGCGFBHH?HCEEEAIFHGHGEDAGAF?CHC?@GBAGFHC@@?IBIG?IFII@CBA@AHCHEI?IGIIG?AGI@FEFGEAEBIDIA
@>chr21:9441895-9441956-1
GAAGGTCCTCAGCCTTTCTGTATCTCATACTGTATTCTGCAAGGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
@BCF?BH?D@DBFAAEAHGFEB@A?@CEGA@B?ICGDECHBDEH?ADCIAFH@B?IA?DACFABHABDDCAHEADFEGE@DHCB?I?D@?IEAF@AHDCH
@>chr21:9441895-9441956-2
GAAGGTCCTCAGCCTTTCTGTATCTCATACTGTATTCTGCAAGGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
D?A?G?F??GHACC?CFFCBEGBFIDIE?CFFCF@IG@AC@CAEAFB@GGF?EAFFHGEFFHH@GAFFCBCBFDCGDAHD@D@CFF?@A@@EGDHDEAIG
@>chr21:9441895-9441956-3
GAAGGTCCTCAGCACAACTTTCTTTCACAGNAGNACCTTGCAGAATACAGTATGAGATACAGAAAGGCTGAGAACGGAAGAGCGAAAAAAAAAAAAAAAA
+
HCA?IF%GDHIA?F?@DIAEIBBAABIBEI0EF$ED@EG@DIGAIAIBIDGHBE@IGGE@CAIFEBEFFCFBE+GIECDBB@@CDGEHGGBFD@@IFDDE
@>chr21:9441895-9441956-4
GAAGGTCCTCANCACAACTTTCTTTCACAGGAGTACCTTGCAGAATACAGAATGAGATACAGAAAGGCTGAGATCGGCAGAGCGAAAAAAAAAAAAAACA
+
?EHBEACB@BC3FBADIHHAAGBH@IFGCCAEDAEGHH@DDHAAG?GHDD$EEAG?CIAACADCDDGI@BGGED@I@+D@E@G@GFIBCEBA@GC@BH7@
@>chr21:9441895-9441956-5
GAAGGTCCTCAGCACAACTTTCTTTCACAGGAGTACCTTGCAGAATACAGTATGAGATACAGAAAGGCTGAGATCGGAAGAGCGAAAAAAGAAAAAAAAA
+
DDCBDHCFACIC?@ECAE@CCCAEABBIBIDB?IFF@D@FFI@@GCDE@?HCIAGFIH@ICIEAIGG@DHG?F?I@GIGDHEGEBFHCFE*CEGHFGAD@
@>chr21:9441895-9441956-0
GCGGCGTACAGCCTTTCTGTATCTCATACTGTATTCAGCAATGTACTCCTCTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
EDD?CIE@FHGFDIAABGIBDCFDHAC?D8EFF?AC'DD?DCF?ED@IDD#AECBHGAIEABDH@BC?IHFBH@I?EABB@@@DDIGE@IDEGBAHDGF?
@>chr21:9441895-9441956-1
GCGGCGTACAGCCTTTCTGTATCTCATACTGTATTCTGCAATGTACTCCCGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
DGFIECCIE@FCBGAH@AGDGHFHHDAFBHD?HACFFAHAG@GE@DHEB(EFFDEBFIHBDEACFFIDBA?DIAGGEDIB??FA?BHFBBDC?IIG@FGH
@>chr21:9441895-9441956-2
GCGGCGTACAGCCTTTCTGTATCTCATACTATATTCTGCAATGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
@EBIFGDH@BG??GF2I@?EBBAEADGIE?7D?IHHA@EH@?ABGHGCHABIGDBDGGCAB@GIFEEA@EHHCG?FCIIDIAIDIIGHFIF@GG@?GEGG
@>chr21:9441895-9441956-3
GCGGCGTACAGCACAACTTTCTTTCACAGGAGTACATTGCAGAATACAGGATGAGATACAGAAAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
GDABFG?AIFB@HD@DACHCHA.BF@HGDCEFECFE??FHE@GD@@HHD)?BDBECEH?F?CA?EGDCH?FIF?A?CFBADFB?DDDHBCIC?AHEFCB@
@>chr21:9441895-9441956-4
GCGGCGTACAGCACAACTTTCNTTCACAGGAGTACATTGCAGAATACAGTATGAGATACAGAAAGNCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
AABHGC@?GIHHIHHBBBBG@*@D@CC@@IGGH@EID?@IEDH?DDGIA?F?IHGBHEAHE@HAF6GBAHFIFHCFAB@BDFCGBBBI?HF@H@GCIBCF
@>chr21:9441895-9441956-5
GCGGCGTACAGCACAACTTTCTTTCACAGGAGTACATTGCAGAATACAGTATGAGATACAGAAAGGCTGTGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
IBCAI?FIB?IF?GDB@GEEIHIDHDG?HA@?I@DEACAHBDAIACH@ABH@ABC?FECBFDH?BCH@D(GCEFCAGEFACF?GGHHBCCCDECH?HFHG
@>chr21:9441895-9441956-0
TCAGACGGTAATCAGCCTTTCTGTATCTCATACTNTATTCTGAAATGTACTCCTTTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
BB@CBGHCE@EGIDI?DB@F@IFCABHHG@F?FB)CBEAHFD=CID@FEIECFB:BBH@DAHGIDHCBFGGAG@GCGCCFDFDHBBFD5BC@BDDIIGAC
@>chr21:9441895-9441956-1
TCAGACGGTAATCAGCCTTTCTGTATCTCATACTGTATTCTGCAATGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
GGFAFC@A@@IHHACFH@E?G?H?CEI@HBCF??@G@@ADEDHFBBIAEIGIF@@FFDEGAIBAHB%GDD?GGHBI@ECFBECGIECDHCGHGCAEBAFH
@>chr21:9441895-9441956-2
TCAGACGGTAATCAGCCTTTCTGAATCTCATACTGTATTCTGCAATGTACTCCTGTGAAAGAAAGTTGTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
CEFB?A?B@AHH@BABECH@DE?!@HBAGCDBEG?I@F?G@EI@EDDCAF?@BCCD@GFHDGHDFEFICEHGEHAAG@@@@?HHH?GECDBFADEF?D?G
@>chr21:9441895-9441956-3
TCAGACGGTAATCAGCANAACTTTCTTTCCCAGGAGTACATTNCAGAATACAGTATGAGATACAGAAAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
?BIBHHBFHEIA@BBAH/I@ACIGBFHEG&F?FBC@D7CCAI#?DEIG?FAEEAE?@?DI@BD@E@BED@CIBEHCGCB@GHDAGDIFF@@CBBDHGAA@
@>chr21:9441895-9441956-4
TCAGACGGTAATCAGCACAACTTTCTTTCACAGGAGTACATTGCAGAATACAGTATGAGATACAGAAAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
EHEE?CDBII?ADAH?EGI?DFE?IFBCDHFAIFGEFFCDA?HC@CACGFHF@FIBIIDC@IFCF@HB@IIFECCGHDHC@?DDAFE?BB@CBACGDFD@
@>chr21:9441895-9441956-5
TCAGACNGTAATCAGCCCAACTTTCTTTCACAGGAGTACATTGCAGAATACAGTATGAGATACAGAATGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
BHAIEH-CBFEGFE@H2@H?AF?B;D?AEDBACC@EDGEACGAC?0B?G?D@IC@GGGCFEDBD?HF(AG?HIIHDIDEIF?CEIAGFG@HIBAICCEII
@>chr21:9452109-9452197-0
ACCACTNTGTCTGCTAGAGNAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGAG
+
@IFHIF0AIG@FABAID?D)AFG?BDBHBEHAEH?GBCH@FBDBCF?FC@EFH?G?D@F?EAG?HHBFDFHFAIABGDGE?BH?@?EHE@DGC@BFCGII
@>chr21:9452109-9452197-1
ACCACTATGTCTTCTAGAGAAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGAG
+
?D?FAAGABIEG%GAEGEEC?H@HI?ACAI?GHF?B@@I@FCIIC?HGCHFF?D?ABI@EHDFH?BFHCIHAGB?F@FEI6IG?DG?IC@B@FI@@GIDA
@>chr21:9452109-9452197-2
ACCACTATGTCTGCTAGAGAAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTAGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGAG
+
FEHGDCAIBF@BHAFFC?IIDFHHEIDGEEEDD@A@G@FI?FGDG?CBIACECBGHDG?IGGEH$EGFIDFEBF@@BAIEDBGHAIAGICHB@IHIBDEH
@>chr21:9452109-9452197-3
ACCACTATGTCTGCTGGGAAGAAAACCATTCTTAAAACTCTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTACNCTAGCAGAG
+
GIF@AC?FG?@@DIGGHAF@?DH@?@HHDGEIG@G2?FI?@A@IHC?D@FGFBFEBED?FFHGDE@DA?DEDFHC@FGAEEBGBDCF06G8E?H?AFF@E
@>chr21:9452109-9452197-4
GCCACTATGTCTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTTCTCTAGCAGAG
+
(CIHDCIHBEGFFCFHFAE??C?GFC??EFHBAD?@IEIA?DC?AFC?GBGHA?@?AGDIBBGHI?BC@FIAFBH?AFEAA?G@DDCAECHE@GEIBEDG
@>chr21:9452109-9452197-5
ACCACTCTGTCTGCTGGGAAGAAAACCAGTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTTCTCTAGCAGAG
+
DACCD@$?DD@GIIGFCDCFGAHFFBGI*EH@CABAEFEBHIAA@ACBIIBI@HFFDBAGCCGD@CCDHBCEEG@IHIBC?IDI@HGAHGB?EHA@GFBD
@>chr21:9452109-9452197-0
CTCATACCACGCTGCTAGAGCAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGA
+
EGCDCECEA?GFH?@B?CIAHFB@BF?CEH@FDG@BGHAA@DIDHIAHDDGCABIHD@BGH?E?HEFEA@EHADAI,?HF?FEH@@AFFDI@EE?@FDBH
@>chr21:9452109-9452197-1
CTCATACCGCGCTGCTAGAGCAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGA
+
IAGBIHHC-GA?EFFHHIGC?@@HCFDGAEBFHHGB@DAB??ECB@FACDB@EI?HBHAHFECIIC?I@HIII@HBIDGEG'EHDD@EBEH?CCFDBBDG
@>chr21:9452109-9452197-2
CTCATACCTCGCTGCTAGAGCAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTTAGAATGGTTTTCTTCCCAGCAGA
+
GAA?HAGF=GDHIGBHI?HIBI?HDBCECBAFFGG?:?HG@GHEEI@?F?CEIE@AFHH<BFCBGCGEF?GB@@DH$E??GGIAGA@DE@?BAFC@BBCB
@>chr21:9452109-9452197-3
CTCATACCACGCTGCTGNGAAGAAAACCATTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTGCTCTAGCAGA
+
AAGCI?IICIIDA@HB@2ECF?IHFCIA@EHEG?@DCGDC@FFDEIHGAHHBAEBB??GH?DII@DII?DCB?DDAFHGGD@C?@GEABHII?GFCIF?H
@>chr21:9452109-9452197-4
TTCATACCACGCTGCTGGGAAGAAAACCATTCTTAACACTCTTCNAGGTCTCATCTTCAGAATTTGCACCTGTTTCTAGCTGAGGACTTGCTCTAGCAGA
+
>EECBAA?A@FBCD?FC@IHCH?CIHDDF?DIBCI?AE?E@H<I(IAH@FAHCFHA%CIF@BICBIBGBIEG@@ECEAB@A@FCECG@AFEHDA?DDBHA
@>chr21:9452109-9452197-5
CTCATACCACGCTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCAACTGTTTCTAGCTNAGGACTTGCTCTAGCAGA
+
IHE?FFHIDI%GBCAHH@ACBGG?F@G@?CEHD@@DB@DDC?HHAIBB@@IEHGDHGI?E?E@EHGHH-FII?BBGHB?IB(F?G@?ADBCC??CIBEAF
@>chr21:9452109-9452197-0
GAAGGTCCTCTGCTAGAGCAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTTCCAGCAGAGA
+
?BBHIC?DICFFIH@FI@GE@FEEFABDIBDAD@?EIIFB@EDHEIDC@@CGB?FDBFH?E9BBDAFBFEEC???FAGIDBDBDEFGFF0EADA?BABIB
@>chr21:9452109-9452197-1
GAAGGTCCACTGCTAGAGCAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGAGA
+
H?D@A@A@9?IFIC@AA?E?G@H?HABDCC@@IF?@E@AFDHFBGGDGDHGIAGF?@CGBFEFAADID?CD?GIEEABFEBEIED??A@FHACE?AHCF?
@>chr21:9452109-9452197-2
GAAGGTCCTCTGCTAGAGCAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGGAGAGTGTTAAGACTGGTTTTCTTCCCAGCAGAGA
+
IF@IAA?@IIEFBBEFDCABFCBCEGB?CDBDAFGF@BHA?FFECB@H@IFG@GHB@HIBGCGAI!FIG@A?EIIDHF"HEHEI@@GGD?CGH@BHHFG@
@>chr21:9452109-9452197-3
GAAGGTCCTCTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTGCTCTAGCAGAGA
+
IDH?DI@D@AGAHBB@DHEDIH@?DH?DFGE@CDIBBA?C@??DDFHIIAA@BA@F?@HHFFBEGC?HAH@E@ED@?@H?FEC?F@AIABFHCEEGCEAA
@>chr21:9452109-9452197-4
GAAGGTCCTCTGCTGGCAAGAAAACCATNGTTAACAAACTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTGCTCTAGCAGAGA
+
AADAF@FGIEHBGIG@=H?GCGDFCBBB$.?ADGB?*9F?DGFCDCDCFDHBEFHA?DCBAFIGBECIFHGCD?@BEBCDEF?HIGADGBCDEB??I@H@
@>chr21:9452109-9452197-5
GAAGGTCCTCTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTCANCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTGCTCTAGCAGAGA
+
?GAEEHC?F?BC@FHFBBCDDDEGAAAA@EA@DHHA?CFB@?AACDD?FDE6A?BGIBCFI@GAEIIDCDE?AFAFECFDF?HFDFEH?ED@EIBHDFE@
@>chr21:9452109-9452197-0
GCGGCGTACTGCTAGAGAAAGTCCTCAGCTACAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTAAAGAATGGTTTTCTTCCCAGCAGAGAT
+
?DGCAHIHDHFF?HD@A?HEHDFFFIHBBEE8I@G@CA<GCEBF?A@?DDFFAGIA@HGFBBGIHDCE?FCC*DADCD@BFCHIGDIAEF@?GCC2FB?I
@>chr21:9452109-9452197-1
GCGGCGTACTGCTAGAGAAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGAGAT
+
CEABGCIEGHIAH?@FIB?G@DBAFIACEDHDBAABFHHBCEDCGGIEEH?GI@BCGGFBDFA@IDAF@IFCE@@A??@?GCAHBAGHDBDBICG?IAED
@>chr21:9452109-9452197-2
GCGGCGTACTGCTAGAGAAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAGAGAT
+
HFHBEHFH?GHBECGB?FFGGD?BHB@GCDDCGGIIGAC@DD?GAA@AEE@IFAH@D@ACGAFG@EEB@AD?EDIGIDDF@GI?C@AGIGGBE?GBIBHI
@>chr21:9452109-9452197-3
GCGGCGTACTGCTGGGAAGAAAACCAATCTTAACACTCTACAAGGTCTCTTCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTTCTCTAGCAGAGAT
+
AB@GFHCHFBAHIG?DAFGEDCGDHA6IEBFAIAE?CICBDBCGBGCBB>C@D@?BD@@CID??@@EC@@:EIFFEABGFCDC@CGEG@?E@CEF@EABD
@>chr21:9452109-9452197-4
GCGGCGTACTGCTGGGAAGAAAACCATTCTTAACACTCTATAAGGTCTCAGCTCCAGAATTTGCACCCGTTTNTAGCTGAGGACTTTCTCTAGCAGAGAT
+
?DGBI?FDEE@9G@ADHEBIGD@DCGCF?G8@EEE@DD?H,D?BFFCAB?4F@FFBIDDBECAI@B@3CCIH<C?HGHEHFCBIFCDGGE@BHHDEECHA
@>chr21:9452109-9452197-5
GCGGCGTACTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTNATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTTCTCTAGCAGAGAT
+
@@@@GGB?CDC@HEAD?BD@CI?AEFABAC@?@GIIFCDIEG@@EEBF!EHGIAIBHFCICA&?@BBFF?EIGBF@AIFDIHABCG@C?DIEB?@A@AAD
@>chr21:9452109-9452197-0
TCAGACGGTAATCTGCTAGAGCATGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAT
+
DCGDGGECH@GDFGCIFH@BFAG0F?BAFEIDC0I@?BGD?CG@IFEAID?FDDCCDAICHD?@H?BH?IB?BED@EEAHG@IA?DBCBE?C@?HAEAD;
@>chr21:9452109-9452197-1
TCAGACGTTAATCTGCTCGAGAAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGGCTGTTAAGAATGGTTTTCTTCCCAGCAG
+
HB@D?@I,@GF?BAIIF%H?CHIDFBHFHFGBHIBD?@EFA?FBFDICCGHD1HHAABGAH@B?ABC?AHD<-A@?ADCEAEBGC@FH@B@IHGEB?EI@
@>chr21:9452109-9452197-2
TCAGACGGTAATCTGCTAGAGAAAGTCCTCAGCTAGAAACAGGTGCAAATTCTGGAGATGAGACCTTGTAGAGTGTTAAGAATGGTTTTCTTCCCAGCAG
+
HG??FIIFGF@?AFEFGA@H?FIABAIH?E@AE?ICHBEGEI?ADFAICHHCIDB@IH?DGDDAGEBEE?HIDC@ADCHEEHHFAE@CGIHE@BBEAF@H
@>chr21:9452109-9452197-3
TCAGNCGGTAATCTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTTCTCTAGCAG
+
@?@I%?DFD@CCE@I?BH?CACIGIBFBB@DI@@EDIEBBIGGCG?HEDFGCFIG:?DEFID@ADCHGIDHGE6BIIAI@HH@?@G?IFEGEFBDFCI@D
@>chr21:9452109-9452197-4
TCAGACGGTAATCTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCACCTATTTCTAGCTGAGGACTTGCTCTAGCAG
+
AGB@BGAHBDAE?I?FAB?DDFH@C@GB?DIEGCABH@D@HEBIFCDG?I@GBDGD@HCGAED@G@DAI@FE;AIAGDGEAC+A@?D?GHBDDEBIIHD?
@>chr21:9452109-9452197-5
TCAGACGGTAATCTGCTGGGAAGAAAACCATTCTTAACACTCTACAAGGTCTCATCTCCAGAATTTGCACCTGTTTCTAGCTGAGGACTTGCTCTAGCAG
+
AIGHABGGCF<A@DFE?FFH@EHF?C@HHDEFDD@I@IFFHAEBGGAHHI?CG@DBH?F@FHBBCGGHCEBGB?DIDHF?IFBCBCC@EFFHEAI@IAIB
@>chr21:9452194-9452316-0
ACCACTATGGCAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAATGT
+
HGD?E+HGI(GIHFA@A@EDHH??G@EBECADHEDFCFAGB?FCC@@HED@CHBDFFFGHGABBFH@H?IGAEDIACHGI@A?HFECGCHHB@GAFAGGG
@>chr21:9452194-9452316-1
ACCACTATGTCAGCTACAGGTAAGGAATAGGAGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTACGCTCCTTTTGGTGATCGAGAATGT
+
H?BCEEBG?GIFAACFFBI@D?HB@FEAIHG7ECI@EG@DDA?EI!G?ECF?HCAA@B?FCAB?GICFEEICAC?3FFF@HFBGCD@FBF?@AFEHE?B@
@>chr21:9452194-9452316-2
ACCACTATGTCAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTNCTACAAACCAATGAANCCCTTATGCTCCTTTTGGTGATCGAGAATGT
+
HHEBA@?CD??ADCHIFDHBABCI@AG?EEFH?FGACIBDHAEBAIC@@EIE.IEG@BGI@E?GBHFI4BFHF@@GI@IEIGFFI@HACGEFGGEHHHI@
@>chr21:9452194-9452316-3
ACCACTATGTGAGCCCTTCTTGATCAACTAATATTTTTAAACACATTCTCGATCACCAAAAGGACCATAAGGGCTTCATTGGTTTGTAGCAGATGTATTA
+
ADDDHAAGGE;IA'GH?AIHA@ECGC(AGIDEFGBHBIHBFGDBFADHABIIFCBDA1I@@AIC=C?EAFAA?IFB@?@HHGEE?EDB?I@?E@BFCGEG
@>chr21:9452194-9452316-4
ACCACTATGTCAGCCCTTCTTGATGGTCTAATATTTTTAAACACATTCTCGATCACCAAAAGGACCATAAGGGCTTCATTGGTTTGTAGCAGATGTATTA
+
@E@EDIGHCA?CGBAGGHAE?F@C$I@CHHF?IADEABDIG@HEG@BC??EBAGGEEICDBIHE(HDE@HEBDEIICGIGIGD@FHEGIDAFIE*C?I?G
@>chr21:9452194-9452316-5
CCCACTATGTCAGCCCTTCTTGATCGTCTAATATTTTTAAACACAGTCTTGATCACCAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGAATTA
+
+AEFG?HFBFIACBE@ADB@@HAA?ACFC?HBBFAI?BAEFGI@D7HFC5D?FGBHIBBI?CDIE@ED@FB?CBF?EEFD@E@GI?HAFBFD@?C6CECD
@>chr21:9452194-9452316-0
CTCATACCACGCAGATACAGGNAAGGAATAGGGGCTGGGCTATTAATACATCCGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAATG
+
@GAIB@BFIEAFG?1G@CGBA/IEICCFECG0DCHBIGAEC@F?IF@FEF@F$GCGCDIDBCI@IH@CHHAGHBIE?H?DIEIFFGBH@@?HEFAB?CDD
@>chr21:9452194-9452316-1
CTCATACCACGCAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTGCTACAATCCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAATG
+
@E?DFGD?EI?EH@CA?BIBCBI??ACHE?I@@GDE?IHIA?DDDF?EDGIHAHDC@@B@(HFIF@EHA@@GDGBD?G@DIH?@CGBD?AA@?CH@F?CA
@>chr21:9452194-9452316-2
CTCATACCACGCAGCTACAGGTAAGGAATAGGGGCTGGACTATTAATGCATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAATG
+
@DAFHEHCEHFGCHCDI?CIFECHA?2DH@G@IAIAGF4H?HBDFAC/IEFBFFE?E@BFBGD@A@?IDCFECFGHGEBEFGIEB@IG?IFFHBIB@CGE
@>chr21:9452194-9452316-3
CTCATACCACGCAGCCCTTCTTGATCGTCTAATATTTTTCAACACATTCTCGATCACCAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGTATT
+
GDAIFAAAEIBA@FBBADG?AACFFIIEEG@GDHH?IGG5HIACI@EAAG??GICDCADHC@G@GCBC@?BAFEI?C?@BEHFADCCIH?GCDBI?BAEG
@>chr21:9452194-9452316-4
CTCATACCACCCAGCCCTTCTTGATCGTCTAATATTTTTAAACACATNGTCGATCACTAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGTATT
+
@FD@CIGGE?:BEI?G?@BH!BF@?IB@DFAAFCIFGG@E@@?FHIG%0HIE?EBH?:@?EBHADBII@?D@EHCBIDH?@IFAHB@ECD?EBBGH?BCD
@>chr21:9452194-9452316-5
CTCATACCACGCAGCCCTTCTTGATCGTCTAATATTTTTAAACACATTCTCGATCACCAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGTATT
+
DBDA@GBIBIFFHIFHIE@@AEHIDFGGAG@CIHADHHGA?AAG@GC@DG?DABEGH.EFD@EIGCH?CBCDHEGB?AIAIGE@FCAHBE?BFAAGEDAB
@>chr21:9452194-9452316-0
GAAGGTCCTCAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAATGTG
+
@B?A?IHF@@HCBH?@HEGIBABFCIID@EBDIHEHCBHHIH@CIDCE?HC@@E@B?BIDH@CI?F?FB@?AEBF@IBCAH?EACHGEBBEHAFBC@DI?
@>chr21:9452194-9452316-1
GAAGGTCCTCAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTATGCTCATTTTGGTGATCGAGAATGTG
+
@CCIDADGI@ICA?HA@?@?BFIDGAAHEB?GIBACBE@B@HHHEGAAB?EB@HG@IACHGDF@?B@EBEEH?E?BBH?1AFDHEBA@EDFDHFHBBBCI
@>chr21:9452194-9452316-2
GAAGCTCCTCAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATANATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTAATCGAGAATGTG
+
HBCC"B?@CDGEDECACGICIGB?AHAHD@ADIIEBAI?CHFH?GA!B?GIDDAC?G?C?HEGDI?@ACBCCF???@FD?HFBDA?B8ICCHCIGI@BAB
@>chr21:9452194-9452316-3
GAAGGTCCTCAGCCCTTCTTGANCATCTAATAGTTTTAAACACATTCTCGATCACCAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGANGTATTAA
+
FC?HADDEC??IBBFAIH@@I@2@?BB@@HFA.DG@EEC@EIHEACAH@IB?FA?B?@GBEA??FECEFAIB@ICDAGGIF@@E@CAFGEDA<BBDGHC?
@>chr21:9452194-9452316-4
GAAGGTCCNCAGCCCTTCTTGATCATCTAATATTTTTAAACACATTCTCGATCACAAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGTATTAA
+
E?C?IDBC<EABGBBCCGDCH@DBFICFE?CCGH@HHCHDF?B@F?EGH?F@EIC!@ECFFABEDICAF@GDH?GHG@@E?D?IF?C4BCHHGFA@CABE
@>chr21:9452194-9452316-5
GNAGGTCCTCAGCCCTTCTTGCTCATCTAATAGTTTTAAACACATTCTCGATCCCCAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGTATTAA
+
@,FAACDDDHDIB?FBFDBAI+@GC@@IA?D@(IFIIG@HC?G@GA?BEHACA1FHEDEFAHDABE@CFCEA?HC@AA?BBEAE@?CCDEB@GI@FBH?H
@>chr21:9452194-9452316-0
GCGGCGTACAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGAACGAGAATGTGT
+
?@GBDGA?HII@HE@@E@GF1??HFDDCBIIECI?AGGCCDIGH?HFHDFHEGEAGAHE@G@EBAIDIHGIGDFHF@?D@E?@B@FHD9C@ABCFIBCDA
@>chr21:9452194-9452316-1
GCGGCGTACAGCTACAGGTGAGGAATAGGGGCTGGGCNATTAATACATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAATGTGT
+
@CG?@FFFBBEAEIIH@HI-GHB@?DI?IEIA?I@?@&CFA@IICEC?BEEFBDCCF@ABEI??BAHFA?GAC@AHDDI?DHAD?C?A?GBGDG?BAC@D
@>chr21:9452194-9452316-2
GCGGCGTACAGCTACAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAATGTGT
+
@CFBF@AD@?CIA?FECHA?@IICB"GCH?@?CICGBBH???CDIDIH@CFBEII?AFCADB??BBH?DD?GHGA?@?DHFAEEA?GCED@@?DDBGEBA
@>chr21:9452194-9452316-3
GCGGCGTACAGCCCTTCTTGATCATCTAATATTTTTAAACACATTCTCGATCACCAAAAGGAGCATAAGGGGTTGATTGGTTTGTAGCAGATGTATTAAT
+
EHFDAHBGDFCCA?DABBGEA@EEIDIE?CHGFEEI@@GEGBCDDAG?CFBICEHDA???HFCBID@AHHE<CH;IHABADG?CACABEIDGIDFBB?@@
@>chr21:9452194-9452316-4
GCGNCGTACAGCCCTTCTTGATCGACTAATATTTTTAAACACATTCTCGATCACCAAAAGGAGCATAAGGGCTTCATTGGTGTGTAGCAGATGTATCAAT
+
?ID4AIEEGE?D?@@BEFEFAADG(CHCAHB@C?GAAFC@FAB?D??D@H?EA?EE?HIC@@EEFH?CBCFI?III@?FCG>DGBBHABAE?BAHF;EGA
@>chr21:9452194-9452316-5
GCGGCGTACAGCCCTTCTTGATGGTCTAATATTTTTAAACACATTCTCGATCACCAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGTATTAAT
+
ADCAAE@?@F??@??D@?C?H@)CGGAAHDABC@DHEBIAHIB??GGHFG@I?AHGB?ED?@AEHG?@FEE?DEGADDD?CG?HIEEADFEEECHHABIE
@>chr21:9452194-9452316-0
TCAGACGGTAATCAGCTGCAGGTAAGGAATAGGGGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTGTGCTCCTTTTGGTGATCGAGAAT
+
@IDCIGIH?ACEEBEH?=HE@CBDHA?CA@ICDE@DIGCAAGACGBBDEDDI@C@GIEGFEGDFADCICE?IECIC7GDIAAHFCCDFIDHE?HDGECBG
@>chr21:9452194-9452316-1
TCAGACGGTAATCAGCTACAGGTAAGGAATAGTGGCTGGGCTATTAATACATCTGCTACAAACCAATGAAGCCCTTATGCTCCTTTTGGTGATCGAGAAT
+
?D?D?@EDFE@FC@EHGHIIDDDACEHEGBCB:B?EDAFDGD?I@IHB?B?@@?DB@EBIB@CGCHE@A@EICHFBEHAC@AC@D@BIEHAECDFHBHEG
@>chr21:9452194-9452316-2
TCAGACGGTAATCAGCTACAGGAAAGGAATAGGGGCTGGGCTATTAATNCTTCTGCTACAAACCAATGAAGACCTTATGCTCCTTTTGGTGATCGAGAAT
+
CBFDBCCCHHHD/GI?D?CC?H.BFC?HB?BDDHIHGBFF@GEDHIHB.F=CA@GGAF?GFHCBFDEFACH*I@EHDEGACHDIGCDAI?HGIB@G@DCI
@>chr21:9452194-9452316-3
TCAGACGGTAATCAGCCCTTCTTGATCGTCTAATATTTTTCAACACATTCTCGATCACCAAAAGGAGCATAAGGGCTTCATTGGTTTGTAGCAGATGTAT
+
DHDCHEHFDGHDFGAAIHE@FCEH?H?CBD@CDBBCA?DF6DHCFABEG??C??BCC@CHHFGIDDEHIB?DDCB?BA@ICHC?C@ACIFEFFBEIHIGI
@>chr21:9452194-9452316-4
TCAGACGGTAATCAGCCCTTCTTGATCGTCTAATATTTTTAAACACATTCTCGATCACCAAAAGGAGCATAAGGGCTTCATTGGTTTGCAGCAGATGTAT
+
D?B?HAEEGAE?HHI?CAC?FEGBEDIHH@GABEGGD?DF??ECABGGE?H@F?FBIGEDE?EDGG@'FGFF?@B@GHAEA?AAFC@I7CHHFIFEFEGG
@>chr21:9452194-9452316-5
TCAGACGGTAATCGGCCCTTCTTGATCGTCTAATATTTTTAAACACATTCTCGATCACCAAAAGGNGCATAAGGGCTTCATTGGTTTGTAGCAGATGTAT
+
@?DEA@HIEC@ID+FECBF?AEI@EFIHIACCI?H?IH??CAGHF@CCGAF?DIFA@BI@?BAIH0BC?@@EF@@@??CEAIAAFIABCIHIIBIGADH@
@>chr21:9455886-9455942-0
NCCNCTATGTCTGCAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
7I?$I*IEAHIBAE?HBFHB?@?CAGGIAA@FG@HBBIC@DHCEHF??DBCAH@IDG@IHE?BAIEEH?HHF@FC@B?FEBDEA??GCGACEDFHFIGEG
@>chr21:9455886-9455942-1
ACCACTATGTCTGCAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTGAGATCGGTAGAGCGAAAAAAAAAAAAAAAAAAAA
+
IEE6AEFD@@H?CFF?ADE@@?C@AGDADHFDDIH?DAH?AEBFF?BHDCAFGE??BIA@GGEHFG@BDD?EH2EGDFAEF??DH@G?CHIHADBFHCGG
@>chr21:9455886-9455942-2
ACCACTATGTCTGCAAAGTCAACACGAGACTTCTGGCCCAAATAGTGCAGAGTTTGCGTCCAGCTGAGATCGGAAGAGCGAAANAAAAAAAAAAAAAAAA
+
GBC@I=IGADDIIEFHGGB??@EEAHFHHI4HGGDADGIA@FC:AABFF?EBAG@AAHAD@?AC?FHGCH@EIHFGAB?IHID*@@IBECE@@@?IFH??
@>chr21:9455886-9455942-3
ACCACTATGGCAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
?EE?EE@BD+G@FBDIBDCCEACG?DCG@HFGFEAIHH?@?@+GFFGFGEHEFF@GIAIGF?F@DFDE@@IFI?ACDIEFA?GBHGGGBCCGGG@IEEGE
@>chr21:9455886-9455942-4
ACCACTATGTAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAACTCTCGTGTTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
FG?BHH@D?DFDCAFCDG?FCCC?BGFBAHAAGF?ECDHCB@@@HF=BEE@DC@@EGB4AC?CGB@CE@EDDE?DEID??AHA?1FIDEDCEIIED@GBF
@>chr21:9455886-9455942-5
ACCACTGTGTAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAACAAA
+
BBIDGE$ICIC@HGB@ADG@?CA@?BFAHIBAFCGHFFECBHGA?CB@F@BEDED@EHHIFDIDFBD?CAC?CGC@AGFCBDHFH?II@AEHI?FD)EBD
@>chr21:9455886-9455942-0
CTCATACNACGCTGCAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
@HGE@A/!GDHA@IBDFA@FF?FAIAB?BF?A?IIIGEHI?AHIFH??IDAC?DBBDFD@DC?CHGAAHGAACDDH@@EICDAD?IG?DEFFG@FCHGCE
@>chr21:9455886-9455942-1
CTCATAGCACGCTGCAANGTCAACACGAGACTTCTGGCCCAAATTGTGCAGGGTTTGCGTCCAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
EFF@?A6EFD@BHHI?B/IHCGIIICCCFIFAAAHDCG@B@F?GAAIBGBF<E?GG?A@FBEI@H?HHCG?FHCACAAFEHH?@HI7EIF?CAHDBI?AC
@>chr21:9455886-9455942-2
CTCATACCACGCTGGAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTGAGATCGGAAAAGCGAAAAAAAAAAAAAAAAAAA
+
FCFADHE@BGIE@F!BG?ACCD??ECDHIGHDEGBFEEHB?EHGB@HCECIFDCG@GFBCGBG?@CHCD?CH@HD?=@@?AHIEHDG@ABF@GI?A@@?A
@>chr21:9455886-9455942-3
CTCATACCACGCAGCTGGACGCAAACTCTGCACAAATTGGGCCAGAAGTCTCGTGTTGCCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
ICG@I@@CFCIGGFH@GBH@BGCIAADF?DBBHD?%BI@EEDDIIGGA@@DDBGECDG%E@CGEGCHHIDACCFBIFFFHHGA?AD@BB@ICCD?GHAG@
@>chr21:9455886-9455942-4
CTCANACCACGAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTNGCAGAGATCGGAAGACCGAAAAAAAAAAAAAAAAAAA
+
CIFD+F@?ADG?FIAGDC?CAIDDHG?E@DBEBEIDEAGGCAIAEID?AD@DEHBCCHBH?A(IDGGBEICAC?IBA@6E@CH?G@BEF?EFBHA?FFCE
@>chr21:9455886-9455942-5
CTCATACCACGAAGCTGGACGCGAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTTGCAGAGATCGGAAGAGCGAANAAAAAAAAAAAAAAAA
+
H@E@GIFFDHBIACCIGHHDEA0H?DIICCIFAIA?H?IEGB?@CFB??@DADHFI@IAH@BD?BECG@@?IHA@ECIDDBHE-@@GI@A?DE@IGBF@?
@>chr21:9455886-9455942-0
GAAGGTCCTCTGCAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTTCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
GGHGBFFFCCHCG@@AIFFFHECGDF?F@?FBFAGEDFEFHIFI?@G@GIIBHI5EFFDADAF@BGGA@IBFEIIBAIFCGIE?C??GH?DHGIFDFFCH
@>chr21:9455886-9455942-1
GAAGTTCCTCTGCNAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
ECH?.DCHG?GBD(DH@IFE@BFEG@@BHEFEC@EFFGAH?4H@CBFIDFDDFHDD@AFHHEEAHG@CF?IE@FD@G@.DBEC@BE@@EGFC@CGEI@BC
@>chr21:9455886-9455942-2
GAAGGTCCTCTGCAAAGTCAACACGAGTCTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
?C???IG?HDA@FBBD?HGHGGDAEAC2EH@?D@AECE@BIAB@AHAB@BEBII?BBBCBIIGH?AFCACBAGGE@E@DFIFGAEABCD?IACG.GHCEE
@>chr21:9455886-9455942-3
GAAGGTCCTAAGCTGGACGTAAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTTACAGAGATCGGAAGAGCGAAAAAAAAAAAAAAATAAAAA
+
BDF?IFG?FD?G?IHHDBD9ACIGH?C@GCGF?@BF@AED@B?IFGHBGADBHHH@F@@D?8EHG?BIF@B?IBBBD?HC@2DHGECAC@HBGI3?AIBD
@>chr21:9455886-9455942-4
GAAGGTCCTAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
EE@H@@BFABAAHAFFB@FEDGF@@?BDBG@GIHFEHACBDC?FDAGFC?ECGD@@IEDFHDD?E@GF@EIFB?AHA?IBI?@AICB?DH@F@?B?BAIF
@>chr21:9455886-9455942-5
GAAGGTCCTAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCATGTTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
FAG@@D@DIC?HDHCGFCAFCGAIICBAHDIFCID?BDGE?CF@@FFCHB-EFIE?CHHEC?DCB@AB@IFECB?G@FCGGB?II?GDABAHHACHBIBF
@>chr21:9455886-9455942-0
GCGGCGTACTGCAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
?FCE@BB@AFAABBEIGDECACIBCDHC?AF@IHFIAB?CB??ADEF@FHCECBI?HDAAFHGHBBA1@CDF?FGA?F@CGEHGA@FGCADF?G@BIBBE
@>chr21:9455886-9455942-1
GCGGCGTACTGCAAAGTCAACACGAGACTTCTGGCCAAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
IAEACIBEHIBAGFAD?IAEG@CACGDG@@?FIBAF9?D@C@CDFDACDIIF?II@IABBGDHI@GAI?FCDFIH@DFBHCFEFI@CAHCIGD?HGB?DF
@>chr21:9455886-9455942-2
GCGGCGTACTGCAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAACAAAAAAAAAAAAAAAAA
+
ICBEAIH@G?CFGCIBFEEIF?CFABIH@FHH?DI@AFE@DHACCIDE?EC?#BAAFGBDFIE%DIF>EGG?DCEEDFHFIC#AGFDAEDCH@C@BFDID
@>chr21:9455886-9455942-3
GCGGCGTAAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTTTCGTGTTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
FCH?ADGHIC?HA?BGCGBH@HG@GBDB@HGAAF@?DDFF@GFBCG,IAIHIE@DDIAEDED@HCBDFD@FIFIAFG@HHEHEFEFFFFBGA@IAAEGBG
@>chr21:9455886-9455942-4
GCGGCGTAAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTTGCNGAGATCGGAAGTGCGAAAAAAAAAAAAAAAAAAAAAA
+
AF@C?F@G?G?@C@IDDIEGABDAHBIDBGEEECCC?ECBGAIE?BF@BIFC@BBGEAABGA0@IIIE?BIG@B=HC@GGGDCE?DC?F?GDFEADBADD
@>chr21:9455886-9455942-5
TCGNCGTAAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAATTCTCGTGTTGACTTTGCAGAGATCGGAGGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
<?B,CBBCCGEECEFBC@CEH?DA??CFAGIH?BCB@FCFB@AB$HIECD?ADBABHGEAHICFEIFBEIDA9ABCGEA@FCCDGBHHHIGI?CIFB?IH
@>chr21:9455886-9455942-0
TCAGACGGTAATCTGCCAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAACAAAAAAAA
+
@HH?BFH?EEF?GAGB0AAHCDBEGGEGF@I@?F@DCFHFAIDHA@AEBIBE?GDAGAIHEBEBAFB?GC@BAIFCCDFDGEGIDHBFHAG7?F@@BGCD
@>chr21:9455886-9455942-1
TCAGACGGTAATCTGCAAAGTCAACACGAGACTTCTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGACAAAAAAAAAAAAAAAA
+
BBBG@CIHC?D?A???FCFCAEBEGCBCFAEHH??@CH?AADIGE@EF?CBIACEHAHC?H?IDG@GHAG?@4GI?I@C?IIF7BCGCIHHFCGA@@I?H
@>chr21:9455886-9455942-2
TCAGACGGTAATCTGCAAAGTCAACACGAAACTTTTGGCCCAAATTGTGCAGAGTTTGCGTCCAGCTTAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
G?G?FHG?FIEEBFECDG??DGCIAHBBE&?IID8@AEHHDBCC@5CIFID@A?GDAICGG@HICIHI@?ABAGI@DAIDFDDFECBC@FA@I?CCCBID
@>chr21:9455886-9455942-3
TCAGACGGTAATAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCGTGTTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
HB@HDBDDE?@GIE@F?@BGBEH??DFD?C@IEG@IDDEHCFCEEGAHCFGCB??EA@C?AHG@?AD@HCAHCDEEF??$CHICIIHDIEEB@GEFI?EE
@>chr21:9455886-9455942-4
TCAGACGGTAATAAGCTGGACGCAAACTCTGCACAATTTGGGCCAGAAGTCTCGTATTGACTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAANA
+
FGCHBAFIAHAI?I@HEGDF@AGGH?GGFD?IIDICGAIIIGCEA@AG?CHCBDF;IEGGBAE?DHHDG@EGDI@HEEHAFDGDD?@DBED@AFH?E@2G
@>chr21:9455886-9455942-5
TCAGACGGTAATAAGCTGGACGCAAACTCTGCACAATTTCGGCCAGAAGTCTCGTGTTGACTTTGCAGAGATCTGAAGAGCGAAAAAAAAAAAAAAAAAA
+
AGFDFH@CCEHBCA?ACDDGDBIG?@C?ABF@ADH@IFF:BEI??BGCE?FI@BADFFHG@DA?IDI?@BBHG/CFBBG?D@AEDHB@H@FIGBA@D?@@
@>chr21:9458857-9459010-0
ACCACTATGTCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAAGGTGAAGTTTCAGTAAAGAATTGAGGAAGTTGAATGAGCTGATCAA
+
I@G@CCGEH@B?AAIIHCCA??AAABDABBAFDABFAFCAGEG?D@?H@AH@E@EAAECIDIFDDGHB@DH?G'GDACHBCDDBBGFBGI??CDIACAAH
@>chr21:9458857-9459010-1
ACCACTATGTCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGGAGTTGAATGANCTGAGCAA
+
BCAAC@GDAEAHDFCFHCD?HGAHCHH?@IHCIA?F?G?GAIHBDGGF@CEF?GIGBB??GI?BCHGC?ECIABFA?GIF2IAFCBDAA?E)BI@?9AHI
@>chr21:9458857-9459010-2
ACCACTATGTCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCAA
+
AII@C@@?AD@EEFDI?DE@E?@@DA@AGHIAGG?C(G?IHFEAAE?IGD?B?DICGB???IFIE@FG8I?D@GIEAB@@C??DDCDF@GE@IBIFFAHE
@>chr21:9458857-9459010-3
ACCACTATGTCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCANTGATCAGCTCATTCAACTTCCTCAAG
+
HBFBEDIHEBECHEHIBC?F@FDGBEHCC?BF@@?FDCGBD@E?I@BEBIHICIIBFCCFBC@FBHGH?CBA?:GIHE@@DCGI?ACCFBDBA??@GADC
@>chr21:9458857-9459010-4
ACCACTATGTCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCATTGATCACCTCATTCNACTTCCTCAAG
+
BEHHFHAIGE@AFDGF?HFC?C@BEFCB??IHHEECE@G?HBCGA?@@@B?DDIHBAD@F?EEGEACFA?CHECEFDAFD<FCBBEHD=H@AHFIIIAGG
@>chr21:9458857-9459010-5
ACCACTATGTCTTCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCAAG
+
D?C@BAIECFAB#FDA?HHACG@@I?CIFECC@DCIDABBD@CGCAGDAGFHAC@EGEIHIFIFFI@?HA@AIGE?G@ED?HEEE@ABIIHC?GAHEBG?
@>chr21:9458857-9459010-0
CTCATACCACGCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCA
+
BFB@@@HEIEBE?FDEHFDD?E@FIB?G?FHHH?DE?HBGEB@IF?DF@H?EFADFFG@C?EGCFEBIAFAIACBCHH6@I?GGHHFDI??GCGGBDIID
@>chr21:9458857-9459010-1
CTCATACCACGCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCA
+
HIGBD?@GB?@IDFGFFDDE?BBAGHGIEAEEE?IAHEBHBCC@AGDIG@I@G?FHDCF?G?@EA?ADD@@B?@CC?DIB@CEDFH?BE@BEFBA@BCIG
@>chr21:9458857-9459010-2
CTCATACCACGCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAATGTNAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCA
+
FDF?F@IFBD@IDAG?AIG?IGFGID@EBBICF@GFEGBIDDAF?FGDACEEDBDGFG-DIB@@GAFHHGCBIH@HCB?IG?ICGDD@DFCBA@A?DIG@
@>chr21:9458857-9459010-3
CTCATACCACGCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTNGAAAGATAGCCCTCCATATATCNATTGATCAGCTCATTCAACTTCCTCAN
+
GH@ABH?C@GFD@GHAFFAE?DADBCHAHIIFHGE?HFEGBDE@A?IAF*??EBBCDD?CBAIF?DIFEEBB9AHAD@F@<@GAIH@DFC?@F@?GDHF.
@>chr21:9458857-9459010-4
CTCCTACCACGCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGNTTGGAAAGATAGCCCTCCANATATCCATTGATCAGCTCATTCAACTTCCTCAA
+
?GA8@F?BFDEA@BIH@HCCEBBB@GGEGGG@?@BFA@?@IGG??F2HBFAFF@?F?AFIEF@@GB:@DDEBG@DE@??D@DCCIGC?HDDAHDECA?DC
@>chr21:9458857-9459010-5
CTCATACCACGCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCAA
+
GHCH@@?FB@@H?E?BGDBDBC@DF@D@CH?FEDDDI@GCI?BICAIHB@HCG@B?ACA1@GIIDI@D?DHDG@?AG@@IDHD@?IB?GG?H?DBGIED?
@>chr21:9458857-9459010-0
GAAGTTCCTCAGCTGGGAGGCAGTTTGAAATACTGAATAGACCTCATCGAGAAGGTGAGGTTTCAGTAAAGACTTGAGGAAGTTGAAGGAGCTGATCAAT
+
AIAA>IEI??CGGGIFH@?DDHG?HHDGHCBBDCBDAGHB!HDAAFC@@BB?G?BAAC:CHCCEIGA@HFAEFCE@?CHIC@CHFHC%IE@BAFBGIA@D
@>chr21:9458857-9459010-1
GAAGGTTCTCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCAAT
+
HH@I@E3BEGAABAABAFHCHFEADIBFACEIFBC@FHGCCCDBEBEGDAICCIDEGHB@??IHEE?B?CGFCGDCBCHGBBBG@AECFEADGAGFED@B
@>chr21:9458857-9459010-2
GAAGGTCCTCAGCTGGGAGGCAGTTTGAAAAACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCAAT
+
IG@CEEIBBGDBCIIBDIBHCGHGHFDGGC/HGHHAIBDGIHBDA?IFBGC?AIHFB@@HFDHCFDFHAD@EHD@AA?HHI@ECAFA@FCGAI@ICCIEH
@>chr21:9458857-9459010-3
GAAGGTNCTCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCATTGCTCAGCTCATTCTACTTTCTTAAGT
+
GB@@HE3?EFDDHHEBICCGD??FIE?IIHI?AFEFHAC@AFFFIAACHE??ADDDIIFE@GBAFICI?EE@BGC;DABEABE*CCF3?I?D/DE;CFHA
@>chr21:9458857-9459010-4
GAAGGTCCTCTGCCTTATGACAAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCAAGT
+
EEB?AHEI@EEG?HHAB?C@@.I@HGGEBGHB@BAHEHGDD?CG?H@DICBIAGAF?HFAIECG@@HAGAHICDD?D?ICFD?@?GEICC?F?IIGF@HC
@>chr21:9458857-9459010-5
GGAGGTCCTCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGAGAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCAAGT
+
C*HDFAIG?A@DA?C?GEA?IFID@F@IGCCIHHE?IDGAG?FEHCAC@D@HIC$BCD?A@?DGEIGG?HGCAAGHAIBDFEIIAAAHA?B?B?HBD?H@
@>chr21:9458857-9459010-0
GCGGCGTACAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAAGGTGAAGTTTCAGTNAAGACTTGAGGAAGTTGAATGAGCTGATCAATG
+
CDGD?DGDCIDHIGDGCECIAGEI?DIF?@GCHHGCEECG?B?FH?CE@EAAEE?GBCEI@?E?FF<IGCIAH?GGAF@HAFBD@DAIB@BC@EDCFHIB
@>chr21:9458857-9459010-1
NCGGCGTACAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAAGNTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCAATG
+
<I?EBI@IEDC@DBDFBAG@EE!CADC@@@CHFFG??CEDC@?HDAI@IHCG?>FEAFGHA@AD??EDDIDDEAAIGAFGABBC?CGA@FBEIFBGEGE7
@>chr21:9458857-9459010-2
GCGGCGTNCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAAGGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATCAATG
+
?@FCBC@)FFCFIDIIGAHI@FBE?BFIAIEFCE@DD@GDGCGBD?G@BIIHCG?H@FCE?C??@EFHDDA@ED@CDDIBI?CB?FE@?I?@FD@FBGFD
@>chr21:9458857-9459010-3
GCGGCGTACTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGNCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCAAGTC
+
D?GBGFFAGAECDGC@@CCCCBCDHCHHBFE@EHDBAEICGCBDBI?CGIDACIGD6@FBGHFIGBCBFGD@GB@C?HEIHGFI?IACIEH@?G@BDAGB
@>chr21:9458857-9459010-4
GCGGCGTACTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCAAGTC
+
E?F@G@A?BBBCDD@AAFEGCGBBDF?B?BIHAD?GEECHF@HHAABCCFHBD@EABE?GDG?ABHCAF?CA?@E@?FEBI@G?ICIFGCFE??G?@HGG
@>chr21:9458857-9459010-5
GCGGCGTACTGCCTTATGACCAAGACTCTAGTTAATTTCTTCGCTTGGCAAGATAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCAAGTC
+
FHA?EGHGABD?HFE?DIC?@@IBH@GGA@EGG@BGGGGCE%G@AHAD>A?CB@DBG?DDE@A@EIIHB?B@@E?GG@AD?H?HGE?I?I?CBBEEDFBC
@>chr21:9458857-9459010-0
TCAGACGGTAATCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAAAATGTGAAATTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATC
+
AGE@BGCHIE?IEHEDCGCBGFEGEHFDAH?@FGF@?BEDGBHBFCIH?I@F@&BCIIFA@I.C?GDIBE@FF@CH@?CBFFBE?@HAGDFIAGIAFDGH
@>chr21:9458857-9459010-1
TCAGACGATCATCAGCTGGGAGGCAGTTTGAAATACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATNAGCTGATC
+
?H?EHHI#@6?DFG?CH?DHBEAIC@@ACEHECC?G?EGI@EDBGB@II@I@?BEABB@@EFIIIDEB@@BFBHAID@GE@DADGF%@BA@0HECDI@CB
@>chr21:9458857-9459010-2
TCAGACGGTAATCAGCTGGGAGGCAGTGTGTAATACTGAATAGGCCTCATCGAGAATGTGAAGTTTCAGTAAAGACTTGAGGAAGTTGAATGAGCTGATC
+
IBDCFIB?HBCHHA@BG?@?CB@CBBH=E?<GFH?ABD?A@GGB@IBGB@IGFCHGIFIH??FD@CABID@EBADFDBB?@EFGBECC@G@EI???DDBI
@>chr21:9458857-9459010-3
TCAGACGGTAATCTGACTTATGACCAAGACTCTTGTNAATTTCTTGGCTTGGAAAGATAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCA
+
IID@@CBEGGEDHBE#@@?EFIFDGA?BI?G@C/@?5HGHAGIGH?DEFDGCFDA@DFBHA?AE?G??F?GCHHIE&IFFBEIIFC@CIDGBB??G@AEB
@>chr21:9458857-9459010-4
TCAGACGGTAATCTGCCTTATGACCAAGACTCTAATTAATTTCTTGGCTTCGAAAGATAGCCCTCCATATATCCATTGATCAGCTCATTCAACTTCCTCA
+
CE?HAEGFEH@?I?5HEIEAICDFB@@BHAAEBA%CEHI?E@@GHFCE@F'BECA@FAA?DF?DA?A@DEHCDCBBFCAFFC?GICF?DBHEBBCADHED
@>chr21:9458857-9459010-5
TCACACGGTAATCTGCCTTATGACCAAGACTCTAGTTAATTTCTTGGCTTGGAAAGATAGCCCTCCATATANCCATTGATCAGCTCATTCAACTTCCTCA
+
C@C6GG?@EBF@AEHBEFCF?HA@A@?FFDHEB?EFAAGI?G??H3HIDEHGA@B??D@I@D@@EDI?@FI+E?ECAIFIFDIIEDD??EIB@DGH?@IH
@>chr21:9466639-9466693-0
ACCAGTATGTCTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
CABC6EGBIEBEFHEFDH?C@FDD?GFIHADDI?DEAHGEEDHBGAEIFDGEFB?C@EA@?FAHI@ECHA@IB@HEFCFG?EHGFHA?A@??DHHC?AEE
@>chr21:9466639-9466693-1
ACCACTATGTCTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGACAGCTTTGCAGAGATCGGAAGAGCAAAAAAAAAAAAAAAAAAAAAAA
+
DC@@BEGHAEHF@IAACBGBF?CF@IHAA@HFIDIIEFBCHFFG?IIBCD?G@I@IDGB@B?ACIEI?@@E?GEFC@1DBD?HEF@?DEAE?IH?FHCCG
@>chr21:9466639-9466693-2
ACCACTATGTCTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGACAGCTTTGCAGAGATCGGAAGAGNGAAAAAAAAAAAAACAAAAAAAA
+
EAH@?FDGIF?A@FHCEDEHHHC@H@?BIBGDAIIHAD?C?I@AIB?FEACFFGIABADBG"?IIADFA>CDCEGC)HH@CCCAA?AEBIC,ECCCC?EI
@>chr21:9466639-9466693-3
ACCACTATGTCTGCAAAGCTGTCTTGGGGAGATTTGCACCGTTAGAGAATCTGGCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
@DG@AIBGAFB@FA@IC@AFHFEDFBBE@IFIAEB@?@GCGHIDEBBFIHH?G+BFIDF@DDGHAEIFIGDAICEHGCEHHEGDHFAECCD@E??GIIAF
@>chr21:9466639-9466693-4
ACCACTATGTCTGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATGTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
EIBFGGAEBCFCHIEAAB@@EH@GCCHADDBB?@BGGC@BFBBDFFACA?<FFIHBHA@DB?EDIGG@@HDIFCH?GCHCFII?GHEIDCBIGBBIBFCG
@>chr21:9466639-9466693-5
ACCACTATGTCTGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAACAAAAAAAAAAAAA
+
EHEGIGGAIEIG@BD???HF@IHIDCHIGBCGHC?E@ICIGIB?@F@H?CFGEFGBIHFDH@FA@@?B?@AAFFBH@AEID?DCBA-HEGHFBHEHEGEG
@>chr21:9466639-9466693-0
CTCATACCACGCTGCATCAAGGCAGATTCTCTAACGGTGCTAAACTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
FCCEAHCFGHCEGBGI@DIGGGH@GA?FD?DHDIDDBFD@)IH0@?@?G@D?CGBDIIH3IE@BHGEC@ID@HBEB?GDGGBCFBCDHGACHBHBF@DBC
@>chr21:9466639-9466693-1
CTCATACCACGCTGCATCAAGGCAGATTCTCTNACGGTGCAATTCTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
HIBGA@DAE@IFCHHHEB?FEEDDB@C?B@HD'EDCFAH?AG,BCFHGGGIHIGIA@HAHADG@DFGAD??HIAHH?BFEIF?GAEE1?GH@I@@GC@IA
@>chr21:9466639-9466693-2
CTCATACCACGCTGCATCAAGGCAGATTCTCTAACGGTGCTAATCTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
B?HGGBGBE@CCCAF@C@HDACB@?F?DEEIHCCC??HHE5HBFBDDA@FEHHIIAEICAIBBEEFIIBHECDGICHD?EACBDGAFAIHABIDHE@C?E
@>chr21:9466639-9466693-3
CTCATACCACGCTGCAAAGCTCGCTTGGGAAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
IBIEHAIIBFICFFAFDCIAE/AHCIF?C#BHDGCEIEDEGE?AB?A@CEIGDH@BGGEBFIH?IEHGHGGEC?B@EAF?EIBGFHFA@@HBIFHGBIAE
@>chr21:9466639-9466693-4
CTCATAACACGCTGCAAAGCTGGCTTGGGGAGATTTTCACCGTTAGAGAATCTACCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
IHHDAF)@H?ICFB?FB@FFGF@G@DIG?ACD?H@A*ABEA@"CIC@@D?IFI%FDHA?BDHEED?DGAEC?BCB?G@HEGB?DBB??7GIFAHC@@GBD
@>chr21:9466639-9466693-5
CTCATACCACNCTGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
HGBFEBG?AE/GGC?BH@AC?CIE@BAGBA?CICIBBC?@BDH?@E@@@A@GDDH??HDHDD?HFHCE?@AA?FE@IHFIFCABDADFGDCIHADBH?EA
@>chr21:9466639-9466693-0
GAAGGTCCTCTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
GCGBCFBDGEI@?FFIHDGIEHEBCDFBE@A?I@BHFBBCIACADCCIEDCCAECHGG@CGIFD@E?H?FEBCIF?CEDECECEIGGHFFAHFGDFCBEC
@>chr21:9466639-9466693-1
GAAGGTCCTCTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
@@G?EFD@AIF@HHAHHI@HIDFH@F@DGFA?AE?ID@HFD?@I?D@?EDFGIEAC?HEHEAGAAEGCA?I@@HGFFBEEC?E@IA@EB@AAIHE@IFGB
@>chr21:9466639-9466693-2
GAAGGTCCTCTGCATCAAGGCAGTTTCTCTAACGGTGCAAATCTCCCCAAGCCAGCTTTGCAAAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
F?FBFAI@E?ADGDEFAH@CE?E;@HD?BIEAF@IIDAHCBCAGHFGFACBB@CD?EG9A?I9FFIEBDHBGAEEDFDADIGHCICC@DAAAB?CFDCII
@>chr21:9466639-9466693-3
GAAGGTCCTCTGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
HHAAEICEDFCBACCACFDF?H@D?EDGAD@HBAACI@@?IAG@CDDIG?BBCHHIHDGBC?GADFIIIDB?CFF@EAFCFCFGCCFCHA@CIA@HC@EG
@>chr21:9466639-9466693-4
GAAGGTCCTCTGCAAAGTTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAAAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
CH@EAF?C@FGGIII@H1FAAGFH@H?H@IBA??C@D?CHGHCI?HBDFB@ECFFB@D?CAHBGHHE@GIED6B@DIICIBBACG?HCEFH@B@EHGHAE
@>chr21:9466639-9466693-5
GAAGGTCCTCTGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
@HH?IEBHIEEHIGHFH?IDICDCGAACEB?FFHI?@FIGBDGGFBFHCB@??BGG@HCAA?ABIHDICH?DFE?EIFBHDCAB?FID@HADFFEFIBB?
@>chr21:9466639-9466693-0
GCGGCGTACTGCATCAAAGCAGATTCTCTAACGGTGCAAATCTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAA
+
GGGHHCIFI@II@BDBG,CHICDBG?HCAIHDID@BG@FDIGABCIHHACI@CCGFAICE?CHAIGGGHG@AH?EAHAFEIGDBHG?ACHHDB@ICEHBE
@>chr21:9466639-9466693-1
GCGGCGTACTGCATCAAGGCCGATTCTCTAACGGTGCAAATCTCCCCAAGACAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAA
+
@HH?D?CBIHBEFDI?EABA"BEGDIDHCFDFDEDGFDDDHFCCAHFBHCGEB@@HGD@AEDDEHHF@ID@??F?B@A?IIHECFFAC?DCFACEE@?HH
@>chr21:9466639-9466693-2
GCGGCGTACTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGACAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAGAAAAAAAAAAAAAAA
+
B@CAAIGB@?AGAD?ECA@D@I?CF@?CA@ABHGGAHEID@H??AG@G@DF@I?HI?HEE@E?BCHH?IAGG@BBEIDEEBCEC%EIGG@DBHG@FFGDG
@>chr21:9466639-9466693-3
GCGGCGTACTGCAAAGCTGTCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAA
+
IHEDBAGCBCHCCGAH@EDIHB?CDDBI@HH?@D@?ECICBGDFDE@AEGECIDBD?HCCI@IBHFFABI?B@BC?CHI?GHFBDFBA?G?E@HC@FEGC
@>chr21:9466639-9466693-4
GCGGGGTACTGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGACGCAGAGATCGGAAGAGCGACAAAAAAAAAAAAAAAAAAAAAA
+
?ABE,?AID@AEECGBHCAEBHHCGG@@FCGIHFFBHD@AAG@FF@HCBGFDDB@CE,F/HBFA@?BH@BEBI?ECH;H@AAFG?EIG@I@AADFGEHAF
@>chr21:9466639-9466693-5
GCGGCGTACTGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAANAAAAA
+
DG?AIHAH?IF@EA@EFICAFDFEHGDHFC@ABAHEEEHBBFEGDGF?@EDFAGAADBFDAIAD@DDHBGB?IDAE?BDFDA@FAHHIBFGIE@:DCIGH
@>chr21:9466639-9466693-0
TCAGACGGTAATCTGCATCAAGGCAGATTCTCTAACGGTGCAGATCTCCCAAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
@CHCFCG@GIDADC@IICDGB?@AA@FB?BHFFGDCHIFB?I'EHCG@7E*@DGHDCAIHGAF?D?DIICG?CEGHH?GC?AGBHEEBDGFHHEHBF?CH
@>chr21:9466639-9466693-1
TCAGACGGTAATCTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGCCAGCTTTCCAGGGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
?ICFHIEAAFC@?@AFGDCDFAAHIECACDCIG@GCBHFDI@@DEFCF?AE?AAGDIHHIA@;DHC7GC??EAHAFGB@@H@IBDBH?AC@CB@IAHHGG
@>chr21:9466639-9466693-2
TCAGACGGTAATCTGCATCAAGGCAGATTCTCTAACGGTGCAAATCTCCCCAAGCCAGCTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
A?E?AICBHFG?EB?DCBCI?CBD?@FEEAG?IFI??G@GIBCH@GG?G@HFAFAD%HH?DIFAFAFI@G@GHAD?DHGB@DH@GFFCHCABGDE?C@@?
@>chr21:9466639-9466693-3
TCAGACNGTAATCTGCAAAGCTGGCTTGGGGAGATTTGTACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
G?GC@?2??IFBGH?AF?CD@IBBEA@GGGGHIHGFCE<FICBDFCBHG?GGIDH@@A?DDIAD?AGAIFI?@IHHGGB?EFEGCHAH?CHEFGBCGHFC
@>chr21:9466639-9466693-4
ACAGACGGTAATCTGCAACGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
<IEA@II@FB??@H?GGE)@ECGIABC?@ECABEB?HCAE@D@DFBFDCAGIGDCCAEBIDAEA?BDIDCAIIDI@FIBEAHF@G@F@@?ABGB@DCD@A
@>chr21:9466639-9466693-5
TCAGACGGTAATCNGCAAAGCTGGCTTGGGGAGATTTGCACCGTTAGAGAATCTGCCTTGATGCAGAGATCGGAAGAGCGAAAAAAAAAAANAAAGAAAG
+
GFF@@AHIF@G?F*CGGF?AGAGHEF@@@ACECCHHIAHC@BGAABBB@AGFBEDACIE@?BHHGCDGEBHH>ECFHD?BEC?@IIECBHG8H?@/DB@-
@>chr21:9468390-9468562-0
ACCACTAGGTCAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTACAAATGTCTTCTACCC
+
I?ID?HA%HCGFDCCEF@IDE?CGADIAIFBEEF?@DDDFCBFIIIHE?@EIAE@GDIGDDEHB?DD?GC?HE,ED@@HBGEG?@@HHHHBHEDBIHCED
@>chr21:9468390-9468562-1
ACCACTATGTCAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCAGTTTTTAATGTACTAGAGGTTATAGGGTTACAAANGTCTTCTACCC
+
@AAIFICIBDCDFAEDEICC?FDHIBEF@CCAACHD??@ECADFBFIGBGHGC$?D?DCFABIHA@ABIFHHHHAF@?ACGDFFFADH7A@F?FB??BHF
@>chr21:9468390-9468562-2
ACCACTATGTCAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTACAGGGTTACAAATGTCTTCTGCCC
+
DDHCIGA?GFBFIAAAECI?IAECAFCHDGDAIHHD@H@EGD6GEFDFBG@@@DBC@GIAFF@FEIHBFCGDDCB?3BIECBEBDHEGB@?BDDCI"HHF
@>chr21:9468390-9468562-3
ACCACTATGTCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTTTTTGCACCATNAGACAAAAGACAAGGGTAGAA
+
BEC?FDIDF@IDDGGDGGH@GIEFH@FFEB@ABHIHB@FC?EBEGIHDA@?HDD@DEC?BBA@BEBFIBGADGAFEAI)A??AG?AIIBFCFIFAHB?@B
@>chr21:9468390-9468562-4
ACCACTATGTCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATNAAATTTTTTTGCACCATCAGACAAAAGACAAGGGTAGAA
+
GE?FEEGGH?AHAGGDCCIBFI@D?FACF@BIDHIBHFDECACCDHIAGDHIHF?FDFGE%FH?E.CEEAFDG@DEFADG@I?B??F@?@DFGI#FDCFE
@>chr21:9468390-9468562-5
ACCACTATGACAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTTTTTGCACCATCAGACAAAAGACAAGGGTAGAA
+
HIBC@H@IA6FCIADAHDIIFHG?EDA?ABIEIEBBH@AHBGB?F?FACFFF?CCDGDADB@@A?G@GHECAFIEAEGBBAGA@BGH@?EFEFAEEFA?C
@>chr21:9468390-9468562-0
CTCATACCACGCAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTACAAATGTCTTCTACC
+
D??DG?CBCFAIAADHGAGFDFCGAFACEBFHDFCEFGAEDFH@HC@FHCCFIBH@EFGEHC?@DBFGAAFCABCD?FB?DGGHDIEB?C?CEIHFE?IA
@>chr21:9468390-9468562-1
CTCATACCACGCAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATTGGGTTACAAATGTCTTCTATC
+
@IAGHCCD@GEC3BB?CFCEGAEIHCA@BD?BIAH@?EAB?EIHA?GFBICEBDDCEFHE?BDEDCCCB?BGIA@CFC2EGHDHCCC@IBACC?IIGF9@
@>chr21:9468390-9468562-2
CTCATACCACGCAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTTCTAGAGGTTATAGGGTTACAAATGTCTTCTACC
+
EEHHA@@HD@AF?FBBCBHH@CDFFC?DF?EGA?FAHGCHBIB@EAEEEGHDCCA?EAB?AAIIEC1CDF@?G?IIF?IEGCEHED@AB?DG@EHG@IFI
@>chr21:9468390-9468562-3
CTCATACCACGCAGCATATTATATATGTCAATCCATCAGGCATTAAGAAATACATCCTTATGATATTTTTTTGCACCCTCAGACAAAAGACAAGGGTAGA
+
GHF?EAFC@CIFC@C@AB@BDGGBDHFCBI?FCCCD@CHIDI@I.@@G?ICCAHE-@?@FBHB7GCFBHDGFFFI@I(IDIBGICCGDF?FEECFEDBGF
@>chr21:9468390-9468562-4
CTCGTACCACGCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAAGACATGCTTATGAAATTTTTTTGCACCATCAGACAAAAGACAAGGGTANA
+
IBC1ACDICG?GBGBIGBAF??IHACA@GIGHFGEAEIIFHHB@AIIB@B0ECI?FH@AC@FBH@H@BABEH@HEFCA?IBEAAAIIHDEEFDGHGFB0H
@>chr21:9468390-9468562-5
CTCATACCACGCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTTTTTGCACCATCAGACAAAAGACAAGGGTAGA
+
CGHIGF@CA?7FEBDGIGGAGIGDCBGAHBACIBBDIFG@CEFBAHGCGFEADDFBD?DGBHGGHFA?FI@AIFAHAECGADGAFC?HA?G??FFBGGHA
@>chr21:9468390-9468562-0
GAAGGTCCTCAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTATTATGTACTAGAGGTTATAGGGTTACAAATGTCTTCTACCCT
+
FF?EAAIFEB@@HEB?FAIAFBDEDEHIGCD@?IAB@@AGFI@AF@DCIAGFEEBEF?G-EI?DG@@BIBDBDFHEAAIIGHBHGIBHIBHI@?DF@DIB
@>chr21:9468390-9468562-1
GAAGGTCCTCAGCCTTTCACAACACATATATGTTAGGACATAAAGGTCCTACCCTTTTTCATGTACTAGAGGTTATAGGGTTACAAATGTCTTCTACCCT
+
@GEB?HC@HCB?CFEEIFCA@EGIBF8BB?CFG??DCHFA?EADDG@EF?2H=$G?GFA:@CIH9BIAIDFEFHFHI@HE@@FBHGE?CIIC?GH@?HIG
@>chr21:9468390-9468562-2
GAAGGTCCTCAGCCTTTCACAACTCAGATATGTTTGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTACAAATGTCNTCTACCCT
+
AGI@CG@IGA@H@IGA@ECHCFF'CDIBHAIH@@=?DHAE??GBIFGE@A@IBCFGCIGD@F@BIABDDHBAD?BHAFDFDF?FICGFHHI;EBFI@D@C
@>chr21:9468390-9468562-3
GAAGGTCCTCAGCACATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTTGTTGCACCATCAGAGAAAAGACAAGGGTAGAAG
+
DEDAFAGB?IAFBB%FEIBEECD?H?IDBFABEHEG@AACDH@AHACBFFBHGDB)EFAFHEE?DIE'A?H?@HDHAD@BH*C@BB?BFEECDDHAGHGF
@>chr21:9468390-9468562-4
GAAGGTCCTCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTTTTTGCACCATCAGACAAAAGACAAGGGTAGAAN
+
BEBBDEDHG?BHACCI?ABACF@AFEH?H?E@??HADAB@HICH?BIIB?HBCA@HF@GGIH?@EHEAACICHFD?FHFHCIGHA?GDH?I@@CAB?@C>
@>chr21:9468390-9468562-5
GAAGGTCCTCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTTTTTGCACCATCAGTCAAAAGACAAGGGTAGAAG
+
AEAB?CEDAAGDABBBGHGAAAF@BCEHGIIBBACGDGDBH+DD@DDIAA?G?@?AEGBED?IEGGA@@CHHA@B?GGDB1CGDGDIDBGH@GAEDDCHH
@>chr21:9468390-9468562-0
GCGGCGTACAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTACAAATGTCTTCTACCCTT
+
IDHDACH@IBEBAEHAEGHBBAICHC@DGAGGE?FDEIFEHDBIIGDEGHFI?F?HECH?BEDAGIEAABDFHIFBDHFIIBA?F?F?AEEEBIE@FGEG
@>chr21:9468390-9468562-1
GCGGCCTACAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTNTTAATGTACTAGAGGTTATAGGGTTACAAATGTCTTCTACCCTT
+
B@C?G&AF?@GHGH@@H@F@GD@GABA@GB@?HAFA@EDEHBDEDIDBIHBD?FC7?@?AAABEEGGHCHCAFACC?DBII?EBHBECHIC?E@@F@@?F
@>chr21:9468390-9468562-2
GCGGCGTACAGCCTTTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTCCAAATGTCTTCTACCCTT
+
D@ADAI?CHF?DABEGGC??EFHCG?GCCEGA@DC?HF@EEEHCH@C?EHAAI?EFGC@AA?IBI?EEIHHGAC@IGBFH?'GEFCFGAACFBFI?IEDF
@>chr21:9468390-9468562-3
GCGGCGTACAGCATATTATATATGTCAATCCATCAGGCNTTCAGAAATACATGCTTATGAAATTTTTTTGCACCATCAGACAAAAGACAAGGGTAGAAGA
+
AGDBCCDE@I?DB?CBE@CAEACC@AIEIFACBA@G@A*DCED?GBEA@CI?@CACEEGBAA@HHBCCDHDA?EHAI?FFFEC@HBGA?@IAEEAH@BFA
@>chr21:9468390-9468562-4
GCGGCGTACAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTGTTTGCACCATCAGACAAAAGACAAGGGTAGAAGA
+
GGI?F@AIGBDHCE@FAHHCIE@HHAHDIH?DF?H@ADDG?IB@HAH?GGDEH@CEDGGIG?FEH5IGAF@@FFEF?HHAGG?CFABH@AIADEF@BBAG
@>chr21:9468390-9468562-5
GCGGCGTAAAGCATATTATATATGTCAATCAATCAGGCATTCAGAAATACATGCTTATGAAATTTTTTTGCACCATCAGACNAAAGACAAGGGTAGAAGA
+
CBICDFBH>DDGD@DBFFCIC@EFIBA@@?-?GCFEHIB?@FHA@BEHAHFIFFCHHGI?@CBEF@HHDHBDCGEAA@EBI8AHHHFBCI@B?@D@BGDC
@>chr21:9468390-9468562-0
TCAGACGGTAATCAGCCTTTCTCAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTACAGATGTCTTCTAC
+
DHDI?FG??ECB@@HEFBAI@3FACFIGFC?FCF@ABBDFHA??BBBEE?@FDGHFBB?EIIAIE?FAEA?CGA?IAEBHIGFIIFCE-D??EFI@GEFD
@>chr21:9468390-9468562-1
TCAGACGGTAATCAGCCTTTCACAACACAGATATGTTACGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTACAAATGTCTTCTAC
+
DH?IIIDB?F?HDFIAICAGGCF?GIHGE?CAHI?GAD(EHDGFB@@HAE??E@@@@@AGDC@EDIGHGCFGHDFDCEBHDFBAAAHIEBAHF@B@@D@E
@>chr21:9468390-9468562-2
TCAGACGGTAATCAGCCTCTCACAACACAGATATGTTAGGACATAAAGGTCCTTCTGTTTTTAATGTACTAGAGGTTATAGGGTTACACATGTCTTCTAC
+
1ECIGIBHF??GIB@EHC;GABHICCCHHA@CGCABHFDAIDE?ADHD?CGBE@?IAF?GFC@CBHC?FCGGEEDEBI@EHAB?EGAF9CBADC@CFHI@
@>chr21:9468390-9468562-3
TCAGACGGTAATCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATATATGCTTATGANATTTTTTTGCACCATCAGACAAAAGACAAGGGTAG
+
@E?F@F?G@@?CGCBBCDCEAIGA?BCD?@BAB?A?AAHGEFAFBEHHA@EDI#AEB?A??A??'EFG@@FIGA@FHGC@B@FIH?GII@IBFDDH@FCI
@>chr21:9468390-9468562-4
TCAGACGGTAATCAGCATATTATATATGTCAATCCATCAGGCATTCAGAAATACATGCTTATGAAATTTTTTTGCACCATCAGACAAAAGACAAGGGTAG
+
@E@D@AEE@?DBG@GIC@IACEEBBHGGGECECG@DIBCB@@IGGCCICH@?BIHIGBBBG?HFCAG?C?ACICEDACF?FC@DDG@GE@BGGI?CBECE
@>chr21:9468390-9468562-5
TCAGACGGTAATCAGCATATTATATAGGTCAATCCATCAGGCATTCAGAAATACATGCTTATGACATTTTTTTGCACCATCAGACAAAAGACAAGGGTAG
+
G?IBDAGGHIEFIDEE@IB@I?AB??,G??DIGGBEHDGDIA@DCHEHGG@EHE?@AB@BDEFG<G?FGGIIIGE@BBDAIBHBF@FGIHGCHCEIBCCI
@>chr21:9472322-9472450-0
ACCACTATGTCTGCTGTAACCAATTACTACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAAC
+
@H@?HBH@ECA@FGDCAI?DACBEDFDIADGG@DHDC@ED?C@EF@C?EGGC@?IH@B@?EI??AAD@@AEA@CHF@BD??EAFCBDEEDIIED@?H@?B
@>chr21:9472322-9472450-1
ACCACTATGTCTGCTGTAACCAATTACTACAAACTTCATATCTTACAANAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAAC
+
?DHH@EHECDD?FHEBHDCC?EGI@AIA@IAECF@HDCGFHBDCFC??1G@DACCEHBACF@F@BEACDCFE@FAGEDEAHGHCEEDIAFGGBE?IADDC
@>chr21:9472322-9472450-2
ACCACTATGTCTTCTGTAACCAATTACTACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAAC
+
E@HA@CH@E?HH#CCHFGIFIIGFIDB?D?@EGC=HDH@HFHBCDBD@E@F?HFGEIIEHII@@HCBAGFIA?ED?@@GCBI@GHACCE@IAHDFC?E?H
@>chr21:9472322-9472450-3
ACCACTATGTCAGCCCTGCCCAAAACTTGAGGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCGGAGGATTAACGGTCACTTTA
+
AHCDFGAHAHBEAA/G@GGIGCGGIAD@ABGHDBAA?BEFHC?BEHFF@CDEEDGHCIDGGADCECBH@EEICGBCGEIC"IHABIBEHG@BAG?HED?G
@>chr21:9472322-9472450-4
ACNACTATGTCAGCCCTGCCCAAAACTTGAGGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCGTAGGATTAACGGTCACTTTA
+
AI1DFCCBFD@AHBDA?GCEHFDGIIF@ADAEF@G?GGFBB@EAFIFEGFFCBA?IBAECHID@DBDIAFCFHGFIGFFIGDBHAEIF?GBGE@?AAG@I
@>chr21:9472322-9472450-5
ACCACTATGTCAGCCCTGCCCAAAACTTGAGGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCGTAGGATTAACGGTCACTNTA
+
DIGAGG?DBEDEAGG@CF@?FFA?I(BGHEGGCDGAHEFIIIHGFCEFEFEFED??DIEI@HDHGAADHGD@ACCH@?@GHIBGAH??BCGBG?ACA)@F
@>chr21:9472322-9472450-0
CTCATACCACGCTGCTGTAACCAATTNCTACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAA
+
FAEDED?GAFBAIH??FF?G?H?CID8H?B@EEIDG@@ID@DIG?DHIBHBI?C@IDGDC?FBDGBHB@EBG@?F@D@CHB@BFGAGHI??FDCC?DHD?
@>chr21:9472322-9472450-1
CTCATACCACGCTGCTGTAACCAATTACTACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAA
+
A@ECGDIAFAHF?@CFDI?AIBD?CCEFH?IIGFBH?@FFIGGFFHDGDEG@EB@G?EED?IHFCGBE?AHDFGFFFBAGGHGDIABAGIDD?=GBFDGC
@>chr21:9472322-9472450-2
CTCATACCACGCTGCTGTAACCAATTACTNCAAACTTCATATCTTACAATAAAGTGACCGTTNATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATNAAA
+
DHG?EHIEDICBDE@?IF?CDI@EI@??F,ICHGB?I?F?AC@IEEAD?@CEIFD?G?H??A4AIG@?GHBEADFDGBBCBGEC@BDEIIABGC?C>IEF
@>chr21:9472322-9472450-3
CTCATACCACGCAGCCCTGCCCAAAACTTGTCGTTANTTAGCCCTGTGAGTTTCATTTAAGGCTNCTGAACTACAGAACCGTANGATTAACGGTCACNTT
+
A?GCGIEEFE?EBECFBCFCABBBD@CGIB,CBBAI+H?AACHCI@GHDCABFHIIFICGFE?G(IICCIHCHGIFIFEDFFF%?C?AIAFFBHEAH>B?
@>chr21:9472322-9472450-4
CTCATACCACGCAGCCCTGCCCAAAACTTGACGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAAGCGTAGGATTAACGGTCACTTT
+
A?DADBB@BC@?EGGA@?D@@?GH@?DEG?IBGB?B?DIFEDBEFBAGCBHH:BIAADCDG?AFIE@HICIDBFCFIG9EIIBAHDADGCICA?HEG@AI
@>chr21:9472322-9472450-5
CTCATACCACGCAGCCCTGCCCAAAACTTGACGTTAGTTAGCCCTGCGAGTTTCATTTAAGGCTCCTGAACTACAGAACCGTAGTATTAACGGTCACTTT
+
FDEEI?F?@GEGDE@AEEAGBBGFIGBCDBE?HIG?C@B?DDC?DA5ED?HBAF@FHABAG?D@.CIG@EEHEDBDIIA@?I@H=GFHB@IB?DEGHDE?
@>chr21:9472322-9472450-0
TAAGGTCCTCTGCTGTAACCAATTACTACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAACT
+
3F?AA?CCCF@ABHH@@HBDFCAIB?CH?IGCCDGAEIBAEHC?A@D@BFFCCB?BIAH@IIH@IC?CG?IIIICAFHBGIHHFIIGBIICIAIGIB?IB
@>chr21:9472322-9472450-1
GAAGGTCCTCTGCTGTAACCANTTACTACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGNTCAGAAGCCTTAAATGAAACT
+
DFABHHCDCI@A?@FHI@GCB3@BF?GAACCG?HHEGHEBC@E?BG?GE@?DEEBCIDGAF?HIDCAIFB?5ICBIEA>DGEAIDC@?EIHCG@EGAHE?
@>chr21:9472322-9472450-2
GAAGGTCCTCTGCNGTAACCAATTACNACAAACTTCATATCTTACAATAAAGAGACCGTTAATCCTACGGTTCTGTACTTCAGAAGCCTGAAATGAAACT
+
ABBC@?F?DFDEE*@GGABBBBIB?B1GDG@B@AFBACF@DGD?DI?CIG@@.EHFBH@BFGBFGFHBCDC??GDEB!GDG@CF??A?H6?DA@IADH?B
@>chr21:9472322-9472450-3
GAAGGTCCTCAGCCCTGCCCAAAACTTGACGATAGTTCGCCCTGTGNGTTTCATTTAAGGCTTCTGAACTACAGAACCGTAGGATTAACGGTCACTTTAT
+
??IACDEIBFFCDDBEBACAIIGE@DDEHFG,?BA?H%HHAGCDDI(G??EIBBI@?@FFICEI@IBBCBE@CHACDAFEE@?HHC@GDIBEGEAH?@D?
@>chr21:9472322-9472450-4
GAGGGTCCTCAGCCCTGCCCAAAACTTGAGGTTAGTTAGCCCGGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCATAGGATTAACGGTCACTTTAT
+
BE.HAEICHHHCF@E?FFHAFHAEE?H?B@@AC@C?DFHCGC=DGBHHD?DA?DFAHEB??FEF@GFHE@HBC?HBD@&FFAGFD@A?CFEHHGECEGDI
@>chr21:9472322-9472450-5
GAAGGTCCTCAGCCCTGCTCAAAACTTGAGGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTTAACTACAGAACGGTAGGATTAACGGTCACTTTAT
+
IADIAH?HBFAFABE?BF!B@IG@BFCE@A?HACEE@BCFBGHBGFIGAI??ECGCAFCEHGGDI/F?ACHA@GDCC)CAAH@FDAABBFF@@?BACDIF
@>chr21:9472322-9472450-0
GCGGCGTACTGCTGTAACCAATTACTACAAACTTCATATCTTACAATAAAGTGACGGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAACTC
+
BCIBIECHAE'I?EDDEB@BBGICAIB?G?H?@HAIFCHI@ACFABE?IAGBDC@#GF@DB??HEIFGBG?EEF@@BADGEDB@GEEGCIHIGHC?IIED
@>chr21:9472322-9472450-1
GCGGCGTACTGCTGTAACCAATTAATACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAACTC
+
I@GAGDHDHDBGDC?FCI?BGA?@7CG?@AB@ADEFDEA@?DHGECEDGB@HFFFDEEGAIHDBEII?GBAAII@FDIGDA?DC@FCHG?@IBHIDBFIE
@>chr21:9472322-9472450-2
GCGGCGTACTGCTGTAACCNATTACTACAAACTNCATATCTTACAATAAAGTGACCNTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAAACTC
+
HBECABHDFC?FHECCG?F9FCAFAGCAHCCBD+@BHID@B@ICAH@@A?C??GF?8GH?DBH@DDFFHG?A?AF@EDEFEG?FI?IF?GGFI?CBIG?B
@>chr21:9472322-9472450-3
GCGGCGTACAGCCCTGCCCAAAACTTGACGTTANTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACCGAACCGTAGGATTAACGGTCACTTTATT
+
HEA?AEBGBD?@HHHD?FEAHCB@AEDB@BE?G;CBDBAGFHEFD@DHG?ECBC?F?GG@ID@?DC@@@BE5E?B??IA@HFFIHBBDBBAHDEA?EGB@
@>chr21:9472322-9472450-4
GCGGCGTACAGCCCTGCCCAAAACTTGACGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTNCAGAACCGTAGGATGAACGGTCACTTTATT
+
DH@BFGG@GEICECDA@A@GBIFHDHAEDBDG@DCABDEEHBEGAACBCH???@@@FFAEI?EHDIFBH2B?H?@DI?HG$ACB'@BEDHEBB@ACAADB
@>chr21:9472322-9472450-5
GCGGCGTACAGCCCTGCCCAAAACTTGACGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCGTAGGATTAACGGTCACTTTATT
+
GF?@GFADHBE@HGIABFIEAHEICHF@C?FHAFDEE@DII?FAFBEEIDIH@ECEAFFDGDE@HI@HFGG@HG@?ACI?DDH?BB??BI@IBGF@ICA?
@>chr21:9472322-9472450-0
TCAGACGGTAATCTGCTGTAACCAATTACTACAAACTTCAGATCTTACAATAAAGTGACCGTTAATCCTACGNTTCTGTAGTTCAGAAGCCTTAAATGAA
+
DB?B@ACAA??IF@IFE@I@IDAFG@HG@HHECFCCCBHB6ID?@IHIC@G??EAB?CDCHDEDBBCHDFDD&DDCIH@BHAB@CCGGGD@D@D??BG?B
@>chr21:9472322-9472450-1
TCAGACGGTAATCTGCTGTAACCAATTACTACAAACTTCATATCTTACAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTTCAGAAGCCTTAAATGAA
+
FFA@@DEADDB?CIBFDEIAGFI?ECB?HHA@FCDCBIBHE@BHBFBGEGCEFBGFBGHI@@D@@FGEAAEDGGHGICGF?DC?I@G@D@FE?B@B?BBB
@>chr21:9472322-9472450-2
TCAGACGGTAATCTGCTGTAACCAATTACTACAAACTTCATATCTTAGAATAAAGTGACCGTTAATCCTACGGTTCTGTAGTCCAGAAGCCTTAAATGAA
+
EB@DCDADFG??IDIECGF?@AEGC@IGCHEHAADBFGBEBIGHB@G.EHAIDBIACIH?I@IB?IAFF?AGA?@GBIBC?G3BBBAICFC?BIBG@C?B
@>chr21:9472322-9472450-3
TCAGACGGTAATCAGCCCTGCCCAAAACTTGACGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCGTAGGATTAACGGTCACTT
+
I?@@FCFAB?BHBICB?HCAHEIEG?IIGHEA?@FIHFD?ABCFFBIGBHAE@IAIDA@FFD?AGEDA?DA@FIABGCGCGI@HFEA@@DBADG@?@@G@
@>chr21:9472322-9472450-4
TCAGACGGTAATCAGCCCTGCCCAAAACTTGAAGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCGTAGGATTAACGGTCACTT
+
DECABDGAICFG@F@CBFIDFCFIEEIHCH@?%I?DHIIF?HDEFCIFFG?GFCHEB??EFD@F?A?G?EDE@@A?B?H@GBDBD?EIEGAAIACCB?GI
@>chr21:9472322-9472450-5
TCAGACGGTAATCAGCCCTGCCCAAAACTTAAGGTTAGTTAGCCCTGTGAGTTTCATTTAAGGCTTCTGAACTACAGAACCGTAGGATTAACGGTGACTT
+
DE?HECFE@DF@IEG@HI@CFFBAC@EAEA*CBGA?ABFHAHE@H@HCEHFH@EHEHGE?IA@CC@BIBEDFHDIDDACBB?FCGGA?IDDFH?D,CIAF
@>chr21:9478302-9478472-0
ACCACTATGTCTGCAATCTTTTATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAA
+
AC@AH@CEBICIAB??AF?GH/CDCDIBGCH?BGDHGIBBCH@E?AA@@FEFHI@CEC?AHACAHCFIHBB?EEGGCEA@ECF@AAIHFCHCADAED@B@
@>chr21:9478302-9478472-1
ACCACTATGTCTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAA
+
F?DHIEGEDA?HI?A@@HDACGEE@HB@AAFBGHCGCGA@GEICADHHHEEDF?II?FAEHBBA?FD;DAHH??@HDED@ECGDH@AC?BE?@?B?BHAC
@>chr21:9478302-9478472-2
ACCACTCTGTCTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAA
+
BF@AHA&@BCGDAG@G?DE?@IHHECEFGFBA?HGCDHEFBDIB??@BC?FDIGEIII?HGI?@BE?GE@A?ECFAAFEI?EHEIEAA?EDEH@HE@ABE
@>chr21:9478302-9478472-3
ACCACTATGTCTGCAAAGACAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCAT
+
DIGGCI?F?G@AD@?CAAEIAGEGHI?EFGC?@FAD?BIH@BGCGFHHCI?EH@FC@?(BAGAA?DI@ABFBGFDEAD?ECHHEHDHFCIEGBD?@BBEH
@>chr21:9478302-9478472-4
ACCACTATGTCGGCAAAGACAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGTTTTCACTTGGTTATTGTAATCTTTTGACCAT
+
H@HGHGCGIIE#EDBEHDEHEGCDAFBGBI@BFBFB?G@B??HBBDBEBC@I@I?IEH@AI@GACGGG1B?HEAIBHF?D@=C?HIC?DEBIGGGGGCCF
@>chr21:9478302-9478472-5
ACCACTATGTCTGCAAAGACAAGNTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCAT
+
EAFD?@EDIEGAF@EHE?C@ECC(AFECBBG@BIII?CCGF@IH?HI?I?EGFEGF@?G?HEHDBAAIBC??BABG@F@FF@AAIB@EAGDHFIFFHDGC
@>chr21:9478302-9478472-0
CTCATACCACGCTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAA
+
GDH?A@IADA@F?ADHGAEDHDC?GEEGBC?AHIBEBHIAI@DGEGBCBCIDGEGDAG@DHCGCBHDCE@GF?GGEGHHIGCCIIIHFC?HHAHEABF?A
@>chr21:9478302-9478472-1
CTCATACCNCGCTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCACA
+
HCCEDF?D6AGGICIGBDADCIHAC@?DCB@@HEGDDABDAIBF@?@HAGEA?IACB@DEBDG@EF@BG??F@I?HAGEIADE?GDE@BIGHHEGFC?!H
@>chr21:9478302-9478472-2
CTCATACCACGCTGCNATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAATCTTTGCCAAAACTCTGGAAAATGGTCAAA
+
GEI?DBEECDAIBGE6CAI?FIGB?@AC@DDCGGG@??EBHIHD@HIGBEED?GIC+GDBC?CECBB@?B0FICB?@B@BGFEEIEFGGE@AEEIGHFHH
@>chr21:9478302-9478472-3
CTCATACCACGCTGCAAAGGCAAGTTAAAAATNTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCA
+
C@HD@HCBDHIG?A?EHBGCGFD@E?F@?BBA#DAGDCCHDDIFCB@HF?F@@?CHCBHDHAIBCFBCF@EGG?BG@AF@?E?AIGBFDGABEFD?AGAB
@>chr21:9478302-9478472-4
CTCATACCACGCTGCAAAGGCAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCA
+
C?FB@AEDCIAHC@HAGCHH@?@DEGDAHBE??DBABADB@GEB??FCEHCC?EIC@E?GHGIADI@HBB@CFF?GEI??GHIFEC?EABB@B??EIA@F
@>chr21:9478302-9478472-5
CTCATACCACGNTGCAAAGGCAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCA
+
AIDB@@FIFD@#DEDEBDIFGDHACAACCC?FFIFECIGHFAIAHFABHB?E@D?C@HEEEAHII?DAAHE@@DG@A?@ICIDABA@FEEIHFCC?IDI@
@>chr21:9478302-9478472-0
GAAGGTCATCTGCAATCTTTCATTTCCCCACAGAAACATCACGCAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAAG
+
EDF@ICE(BEHDHHB@HEHFHCACHC?B/BCCAHDCCHHIAB=F@GG?BCFDEEECEAABHADG@@HHIAFGBGF@?@GGCACACIACAAI??@BDAHBF
@>chr21:9478302-9478472-1
GAAGGTCCTCTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAAG
+
CII@DG@?B?FAEGFFIDGEC@FDIACBE@ECCA?ID?IBIFIHAFHGAF@ACBCAFIGIGAHEHE?EBEGIECFBDHIBHDIFG@D@EB5DDF?A?IAC
@>chr21:9478302-9478472-2
GAAGGTCCTCTGCAATCTTTCATTTACCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAAG
+
BIB@?@GHFII@CIGFFIC@DFCFE4?DFGCADFI?FIEADAGIG@IG@DEIHICBGFGCC?FDG@IG@?@BHBGCH@CFD?IHFFAEIHG?CG@EEDEH
@>chr21:9478302-9478472-3
GAAGGTCCTCTGCAAAGACAAGTTAAAANTGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCATTTGGTTGTTGTAATCTTTTGATCATG
+
IGAGFEGBD?CAC?BFGBE?IBH@DF@A7FGAICG@C?AIIC??BH@CBACCCGFII@IEDFGIFI@FBECGD7CHCII@FCEBIDFGII?@HF@5C?E6
@>chr21:9478302-9478472-4
GAAGGTCCTCTGCAAAGACAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCCTTTGNCCATT
+
HICDGGG@@@HHDFC?ABHA?IFED?G@@AGCCEG@FDI?F?AAHHDCHFAHEBEAI@HFIEHIEEAHFAHFBE?BD@?EFDDFEG?G?!?DED$A?FIG
@>chr21:9478302-9478472-5
GAAGGTCCTCTGCAAAGACAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCATT
+
?@CFC?IDFAC@IB?FBGB@HFEDH?@@BHG@@BADFEB@BEEGA?FGHDACAFH?BH?BAFABI?AICBC?CHDIE@?II@IFGBBFIIAF?C@?CCCD
@>chr21:9478302-9478472-0
GCGGCGNACTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAANTCTGGAAAATGGTCAAAAGA
+
H@HHIC*A@FBCDAIEGEHEEA@GCBH?H?IGAC@IIAHHBFFHFG?HEH@GAAEFEFHEEAD?EA?E?F?IFGBIHE@;EFAD?@CA@HHA?ADCCFAH
@>chr21:9478302-9478472-1
GCGGCGTACTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAAGA
+
E?BDGDCGA?DIC?ACCDD?BFD@HIFH@GIIF@FAH@DCCG@IHGHGEIIDAEIG?@CCADHG?CICE?@E@II?DECF?BECBFG@AGCDICBGI@?E
@>chr21:9478302-9478472-2
GCGGCGTACTGTAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAAAAGA
+
AH@DIAIDHDI'FCFBAEFDD?B@IB?HFCEIIFG??GDF?CAAC?EAIIHDBH?EDDFB@DA?IFFIDADCCFDF@BDGG?EAHFDA??DH?AFBCCEE
@>chr21:9478302-9478472-3
GCGGCGTACTGCAAAGGCAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCATTT
+
@EFCIDEFIDCH@IEIEFH@CAG?HH@IHFCAA@FCD@G?FDACEIIAC?FFHD?DC@GGIEA@ECAA?DAEGD?DA@FA@CFHG@FDD?CFE?HECA?I
@>chr21:9478302-9478472-4
GCGGCGTACTGCAAAGACAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTCCTTGAGTCTGCTTTCACTTGGTTGTNGTAATCTTTTGACCATTT
+
GDHIFDAEA?CFII@GGCHABGEGICH?CGHCI@DI@?FDFDFAAGC?CDHGGGA4A??GHB?AIAF?CBDIEAI?HHBFB9@ID"EABGBD?BGE?DBC
@>chr21:9478302-9478472-5
GCGGCGTACTGCAGAGACAAGTGAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACCATTT
+
HEEACG??AG?@F(HD?EBI?I/?CAEIEADBHG??F?EAC?AFE@I?A@DII?C?AIAIDFGBEFBAIADD?@DEAFGBBHHIF?B@CF@HFHDGIGGE
@>chr21:9478302-9478472-0
TCAGACGGTAATCTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAA
+
@G?AF@AHF@IHHIAEBAFF?IEEGFEIA?HH@HEDI@?@@BHBHGCDDICHCBHDCFA?HFA@EGGDHEBAFCA?C@BICAIDHHCFAHA?ECBGAC@B
@>chr21:9478302-9478472-1
TCAGACGGTAATCTGCAATCTTCCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTNTCCGAATAAACTTTGCCAAAACTCTGGAAAATGGTCAA
+
IAHBE?@BI@DAFDGEGCDFG@"FCHI@ABBI?HG?@FFDEGA@AEAHIEIF?BH@AH?@G-?IHIGD???FCICB?CIAGE?HGFIE@DFGBEGDIAC,
@>chr21:9478302-9478472-2
TCAGACGGTAATCTGCAATCTTTCATTTCCCCACAGAAACATCACACAACTAAGAGAAACTGTCCGAATAAACTTTGCCACAACTCTGGAAAATGGTCAA
+
IBCFADEIIB@GGBE@IAH?BICB@?GCCE?IIEDFHABD@FEDIE@DCIGFFFGB?GEIBEFEFDAFE?H@DIG?EIHF*DBBAGBF?DAIFI?@I?AC
@>chr21:9478302-9478472-3
TCAGACGGGAATCTGCACAGGCAAGTTAAAAACGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACC
+
GA?GIBAF(IB:?@BEH4EDDDB@EHCAFFDC"DBH@B@FE?FGBACEDBBCFF@??DHG?IFCCH?CEAF?@?BF?BIBGBEIGFECDE@EAAHHEAGA
@>chr21:9478302-9478472-4
TCAGACGGTAATCTGCAAAGACAAGTTAAAAATGTCATAAAGTTTTCAAGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACC
+
EAFC?GID@CDCFFC?HGFCA?FBCFBEDIAH?GDEFCCFHE@C?@H@BAIIFBE@BIAGICIEBEEACG?AAI?FGE?ACICBC?ACG??BGB?@IFDG
@>chr21:9478302-9478472-5
TCAGACGGTAATCTGCAAAGACAAGTTAAAAATGTCATAAAGTTTTCATGTTGTCTTTTTCTTGAGTCTGCTTTCACTTGGTTGTTGTAATCTTTTGACC
+
I@C?DFFICFH?FB6BBCDI@BB?BHA?GHB?DFFE?DIIDEHDGAEC(BF@GHEAEG@IGFFDF@?FCI?FCFG??FI??FFD@HDH@FDEBHHCDIFA
@>chr21:9488438-9488522-0
ACCACTATGTCAGCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCTCCTCTGCCATNCCCATCTCTTTGACTCAGTCCTCGCTTGCAGAGATCG
+
D?@GIEFEAHD@DDE?DC@@BBEGEDEAGCDDIBGGDDIDEABFGEHIG@IIF@FH@EGFCG5F@F?EDG@G,DGHABG?GBDGGFAHDDIFEF@F??GF
@>chr21:9488438-9488522-1
ACCACTATGTCANCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCCGACTCAGTCCTCGCTTGCAGAGATCG
+
I@FAECGHGI@?+E?AC@HEGD@@FBG?EH?HEAGBCDFHGGGF@CDICIHCAE@@DCICFD?A@DGGFDDAD<EG@B@BGACHBFDH@CCEEGGAHFEA
@>chr21:9488438-9488522-2
ACCACTATGCCAGCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCTCGCTTGCAGAGACCG
+
HICBBDADD(A@@BG?CDEFECGBE@D@EC?C@ECECHGIBAEHDCEDFCCFEHIFF@GIACDBECAFDCFC@DDGD??IAD?ECEEE?G?A?FA@C+?E
@>chr21:9488438-9488522-3
ACCACTATGTCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTCAGGGCCGTGTAAGATGTGACCCTGCTGAGATCG
+
GAEFHH?GDHICIIEHBHGGDCD@HAAIIFB?HHAGEAG?HBBBAIFCDBB@EEGDAC@EF?HEH?AHF?@?BBGA?@D@AEICH@FGIEG@HFGHBDF@
@>chr21:9488438-9488522-4
ACCACTATGTCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATATGGTCAGGGCCGTGTAAGATGTGACCCTGCTGAGATCG
+
AEEDFH?GH@IEIIFC?@?ADDHADEGHAGBDC?F@FC@HECGBBGFDHECD?ABDIDBFH/B?HEGDID@D@BDFBDHHA@GCHIHBEHAGBC@EFHIG
@>chr21:9488438-9488522-5
ACCACTATGTTTGCAAGCGAGCACTGAGTCAGAGAGAGGGGGATGGCCGAGGAGACAAAAAGTGGTCAGGGCCGTGTAAGATGCGAACCTGCTGAGATCG
+
AHBGHG@@AI2IAD7AH@B?H3HFCDDAGCIBBICA?"CFFAAABCE-IIDBHGE?ABGG&EIG@CD?CCDCIICCGCFIGI?)AH>CDFFF?HEFFIBG
@>chr21:9488438-9488522-0
CTCATACCACGCAGCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTTTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCACGCTTGCAGAGATC
+
@BFFEHDFFCCIADE@BDB?A?E?FF?FAHBEE@B@IDABDHE?CC@GCBF8@DH?AC@DBIFAE@IBHCECCCDIHIGCCD??B-DBFCCF@HFHFHHG
@>chr21:9488438-9488522-1
CTCATACCACGCAGCAGGGTCACATCTTACACGGCCCTGGCCACATTTTGTCTCCTCTGCCGTCCCCATCTCTCTGACTCAGTCCTCGCTTGCAGAGATC
+
BIE?GHBAFBH?GHBI?CCEFI@AEEAA@BFGCEAGIG?>AEGHGECFDCFAEFFCHIG?A)8CFAHEIH@H?FG?CICHHGBICAB@ACEC?GB@GHG?
@>chr21:9488438-9488522-2
CTCATACCACGCAGCAGGGTCACATCTTACACGGCCCNCACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCTCGCTTGCAGAGATC
+
FI?B@EHFGF@AE?BBBABIFDHHGBGABFBC?FBBC+%D@ABDA@?FIICEBAAIGEFC@H@GHF?HBBGCDFGAHA?DGDIGIH@FAG?C=G@@?FG@
@>chr21:9488438-9488522-3
CTCATACCACGCTGCAAACGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTCAGGGCCGTGTAAGATGTGACCCTGCTGAGATC
+
??HCAAAHGCAEHDGBI&DDA@?GFEEGG?CHH?B@G?CAAAF@?H@EDGHFIADEACFADCGB@A@?GGFCHHCGGI??@IA?FFD?B?BFBBFID?GC
@>chr21:9488438-9488522-4
CTCATACCACGCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTCAGGGCCGTGTAAGATGTGACCCAGCTGAGATC
+
FAIECCFFBBEID@D@@BFAFICDAHAFI?HHDE@HFCAG?ECCGADFECHDC?AGAGFGBBBB@H?@DA??BG@B?C?B@FGAEH??HE&?F?FBDHAA
@>chr21:9488438-9488522-5
CTCATACCACGCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTCAGGGCCGTGTAAGATGTTACCCTGCTGAGATC
+
HCIBCHAG@HF?DFECG?CF@BIEDEFHA??EFDAEDBDAI?DGIHHFI??DGAHFIDCF@BAIHC?GFHEGGBBG@EAIFCDFI#DDAA@CBCHGIB?A
@>chr21:9488438-9488522-0
GAAGGTCCTCAGCAGGGTCACATCTTACACGGCACTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCTCGCTTGCAGAGATCGG
+
?CC@CIAICFA@FFBDGHG?@BCFHA@C?ADFBBCEGIIHBCCFIDAFB?HH?HBAGDGAFEE@AG?CGFGIBBF@EFBA?A@IHFFCECE@IHGDD?CB
@>chr21:9488438-9488522-1
GAAGGTCCACAGCAGGGTCACATCTTACACGGCACTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTNTGACTCAGTCCTCGCTTGCAGAGATCGG
+
DGHBGEDD8IGDFB@GEFFAD?HAFBFEBBAAFIIGBDHE?IHD?FD?AGHBAI@B@IEAIBC@G@GGHCH!@"HGFEECAI??EHAAHIAHBBFEE@@H
@>chr21:9488438-9488522-2
GAAGGTCCTCAGCAGGGTCACATCTTACACGGCACTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCTCGCTTGCANAGATCGG
+
IEIHEIAC@@F?HI@FFIEH@DDABCBCHB@IAG?E@G?DDEGFCEIBEHACEBHHBH?IIBB@IDCGG@CA@HIHFFF@?I@CBD@DEA?@9CAIADHI
@>chr21:9488438-9488522-3
GAAGGTCCTCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGANGGCAGAGGAGACAAAATGTGGTCAGTGCCGTGTAAGATGTGACCCTGCTGAGATCGG
+
GHCGAEAH@HCEICBIHBBFA?HE@GEEHGDBIHHAHHFDGD%BBHGCI@GEBB??EHABFGDDFBHBFG@HA??@EAEBGG?II?CB?EC@CGGEHEGI
@>chr21:9488438-9488522-4
GAAGGTCCTCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTTAGTGCCGTGTAAGATGTGACCNTGCTGAGATCGG
+
IG?DIGEADGFEBCH@?BI@I?DIACEGIB?FBEA@AIFAHHH@BAHIECCAE?GDBD@DIGEBE3@EID?@ECH@DE?A@@BGCEH-D?BACADGCBGG
@>chr21:9488438-9488522-5
GAAGGTCCTCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTCAGTGCCGTGTAAGATGTGACCCTGCTGAGATCGG
+
G@HE@EBEADHHCIIFDEDEACFF@CBFGA?EGED@@FFCCEGAG@@BE@EBHGFFGIH???@HF@CECDGIDIG?ADCDADGC@@BEGEEEH?HII@AC
@>chr21:9488438-9488522-0
GCGGCGTACAGCAGGTTCACATCTTACACGGCACTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCTCGCTTGCAGAGATCGGA
+
GFIAECIFEDACAEB'@@?DAAHDCAEABDCCIBDAFCI@EBHF?C@CBFAA@BHFGA?EC@BHCE?@EGC?AAFDBA??EHDBBIC?FIECHBHCFAAD
@>chr21:9488438-9488522-1
GCGGCGTACAGCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCTCCTCTGCCATCCCCATCACTCTGACTCAGTCCTCGCTTGCAGAGATCGGA
+
D>F?GBB?AEAFAIHAHE?E?AFAAGBEDH?BHFG@C@ACC??BDEBI@AE?CBCFIFGIF?ED@AA+EAGC@CIDIHH@ADHGA?FIEEG?@FA??DGH
@>chr21:9488438-9488522-2
GCGGCGTACAGCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCGCGCTTGCAGACATCGGA
+
?HF@G?GGG?FBHGC@@HFBDCFGIF@IAIEAEAHDHF"I?H?BFIBIGIIBDGIG?HADH@@HIAC@DHE@C@GECCHAEF5HDEB@@CFII:BA?FBE
@>chr21:9488438-9488522-3
GCGGCGTACTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGACAGGGCCGTGTAAGATGTGACCCTGCTGAGATCGGA
+
@I?CC@CBB@BEEFI@FDF?FC@AI@FGHFEBIIFIBF?ACFHBFHH@CG???HGB@F?EBEH0C@IAC@C?EIBEDCAEAAF@EAECAEDED?IIBD?B
@>chr21:9488438-9488522-4
GCGGCGTCCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGAGAGAGGAGACAAAATGTGGTCAGTGCCGTGTAAGATGTGACCCTGGTGTGATTGGA
+
HEGCEGD7?ECBG?BIEBHCBE@G@A@GCACHHIBGAHE@ECI*:?CEFDDEE?BF??E@@D?@CHCC@ADFAEIG@CICFECI@EFFC-FF9AAF$CDH
@>chr21:9488438-9488522-5
GCGGCGTACTGCAACCGATGACTGAGCCAGAGAGATAGGGATGGCAGAGGAGACAAAANGTAGTCAGTGCCGTGTAAGATGTGACCCTGCTGAGATCGGA
+
EBFF@ADBHIDHIE=AG@&H@IBFGI6?IGHBBEGC7BI?AEAFEDGABAGF1EEBCF$I?$HEG?FF@@?HCHEF@?DC@@?EGF?FFGCDIGCB?AAI
@>chr21:9488438-9488522-0
TCAGACGGTAATCAGCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCNCCTCTGCCATCCCCATCTCTCTNACTCAGTCCTCGCTTGCAGAGTT
+
@@EBHHAE@F??GEFBCBAC@?@FGCCEE@CHAIEAHEECIABECHHACFACE,E?FIBDG?HIACICGDACFBEA8ADFDGB?F@@BEII?IBI@DG9E
@>chr21:9488438-9488522-1
TCAGACGGTAATCAGCAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCTCCTCTGCCATCCCCATCTCTCTGACTCAGTCCTCGCTTGCAGAGAT
+
GEIDCDGABCIAI@ACGIDDBBDB@A7FDDG@E?FFF@??A@C?ADHACI??BFDHCCDCCAABIA@ADIB?DGEEBDHB??CGDE?AIFADBCCGA??H
@>chr21:9488438-9488522-2
TCAGACGGTAATCAGNAGGGTCACATCTTACACGGCCCTGACCACATTTTGTCTCCTCTGCCATCCACATCTCTCTGACTCAGTCCTCGCTTGCAGAGAT
+
H?BAIGFI??CIBF?>DBHAFDAFFACDBFHHACGFFHA?BAHHG?GC@BA*C?CDBAE?CF@B?C;DGH@DFDAHAHBIDIDBEAHGA??DEDIH@EAG
@>chr21:9488438-9488522-3
TCAGACGGTAATCTGCAAGCGTGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTCAGGGCCGTGTAAGATGTGACCCTGCTGTGAT
+
IDF@GA@FABFDGCDFHAD?D*FB3@DCHIA?BIDDEEHH@?ECBFCFHFAB@?A?FFB?DECFGI@IGA@?C?EACBFFGHECIIIECFC?DB?@1H?D
@>chr21:9488438-9488522-4
TCAGACGGTAATCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGGCAGAGGAGACAAAATGTGGTCAGGGCCGTGTTAGATGTGACCCTGCTGAGAT
+
DIDE@DHEAGG@IHCCBGCF?GC@G@GCEAFGAFBGED@HGFHH@GGACEH?HCDBFGIGB@?EDECGDHID@CIIBDD.CHGIHEB@HC@GAICDGGAA
@>chr21:9488438-9488522-5
TCAGACGGTAATCTGCAAGCGAGGACTGAGTCAGAGAGATGGGGATGACAGAGGAGACAAAATGTGGTCAGGGCCGTGTAAGATGTGACCCTGCTGAGAT
+
CG@@GFFGHCDD@BEIHC)HEGEHFBGFBGFDGGBIHIBEB@AGF?F4C@CEICDEDCHEEHBADHHDDCE@EEBBHEFBHIAB?CE?AFB?AH@ED?@@
@>chr21:9501965-9502114-0
ACCACTATGTCTGCCTATATTAATTTCTATTTTTNTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTAAG
+
I@AC@CFIABG?FCIHCIHDBA0GIGI?FHACDG3HCIH?F@FFHC?HFCE?BHD?EFAE??C@?FI@E@CD?IEGGGAFD?ADBCACG@FDDIEFAIBD
@>chr21:9501965-9502114-1
ACCACTATGTCTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTAAG
+
F@EGECEDFICC@ACHA?FF@??@E@@EB?E??HG@D?@ICFG@CIEHD?DC@AIFH?IHABFI?DEI?EDH?CI?DF?GDD?@CDIEHG@@?IGF?A?D
@>chr21:9501965-9502114-2
ACCACTATGTCTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTAAT
+
B@CHGFDFIFCDHBE?BHDH@EB@BFI@?GABAIHEEHIEAEGFGGHAIEDI?@DBIGHIDBGDCIGACBCDIIECG?BEABHEDBEC??A@IF@CB@H6
@>chr21:9501965-9502114-3
ACCACTATGTCAGCANAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAGTTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACAG
+
A@FDFHDFC?GHBBG:CAFCDBD@GDFHBIFHHCAIDEI@CGB?EBCFDAIAFBDAAHHBEI@D@IG@BDCFFACHAIADAHDEGB?IDCHH@C@H@FDG
@>chr21:9501965-9502114-4
ACCACTATGTCAGCATAATATTNAACTTTAGAAGAAAAAGCAGCTTGGACCAAAAAGAAATTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACAG
+
I@C?IG?DGFG@?CA?AGCCFG3FHIBF@CHDIFHFHBE?>?GE?C@GBGC@HEICGBCABH?ICDAFDGCBIFHCEIFIB?BD??D?DEADI@I@@C@E
@>chr21:9501965-9502114-5
ACCACTATGTCAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAATTCCTTGCCCTCAAAAATGAGCANACCATAATAGACACAG
+
H@@ACF@?FBHIGH?DFB@C@?EAB@BHH??HBFIIE?D@FGFE?IA?I@BHD?CH@FC@B?FFFIGBAHH6EFFIE@AE@BD0GG??GGECI@CIHBGC
@>chr21:9501965-9502114-0
CTCATACCACGCTGCCTATATTATTTTCTATTTATTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCNATTATGGTATGCTCATTTTTAA
+
BHFH@IGEFACEF?@?HH?A@CBCB?FEDC?BG#HIDCE?BCGGCAEBE?GFGAIDA@CBA?@ECH?A@FG?HA?GF0@HGDAA?HAIDH@?EI@CAAGH
@>chr21:9501965-9502114-1
CTCATACCACGCTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTAA
+
E?BG?ED?E?BBCEE@CFAAEGFCA?CE?CCADGFEGFDEGC?@FHGA?CDBBDD?FCECG?BFC?AB?BFGBHE@I@?CG@FFAEBG?A?FFIGA@I?B
@>chr21:9501965-9502114-2
CTCATACCACGCTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCNTCTTCNCATGTCNGTGTCTATTATGGTATGCTCATTTTTAA
+
@AAIG?CBBEIEIFBHC?BDDI?@BGFBAAFBBCAFI?GGEAGFA@?BH@FA?CBIH@/IHFBB<EDA@DB.ABBF?GA?AEAGBA@BBG?H?DGIG@EF
@>chr21:9501965-9502114-3
CTCATACCACGCAGCATAATATTGATCTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAGTTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACA
+
CDFGC?A@DAHGI?@HFDAIBD@HH7G/B?ICCC@BFCCDDHBDDADFDDFA?CH@DEHE@IBBE?GCFD@DIHEHG@IBII?B@BHH@HECCGEEFIBH
@>chr21:9501965-9502114-4
CTCATACCACGCAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAATTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACA
+
FCDIAGBBFEHBF?DFHI@BDAE?GBFBIAEFDIHA?FD?CF?FACDA@?DDA@GCHFIABFC?FBHIGICGCHG@GBDDFF??BC@DFIHFBFEDFBGA
@>chr21:9501965-9502114-5
CTCATACCACGCAGCATATTATTGAACTTTAGAAGAAAAAGAAGCTTGNACCAAAAAGAANTTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACA
+
HDADGFGIH@E?DAGIFH%BGCAFGG?G?EBEAGDGH@DCCGDFFGE?)EIFG?CCGFCA%GAIDBECHE@CC?FGG@H?@FGFFH@HGEICHHBEIHBE
@>chr21:9501965-9502114-0
GAAGGTCCTCTGCCTATATTATCTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCGATGTCTGTGTCTATTATGGTATGCTCATTTTTAAGG
+
BCBCBAGAC?HFIA@FE?IBGG!HHEBI?FDBEI??A<HCGACHDFA?D@H@EEC@??BBBH!5CGHHA?ECHA?BHDHBFGBGECEF@CFI@DGBIBDE
@>chr21:9501965-9502114-1
GAAGGTCCTCTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTAAGG
+
H?EEEABIDABF@@CIIEDBDBAEAIBA@@DC@BCA?E@D?DIDFBEAIGEHGCGIIFABEIIFFCEE?FF?F?HHFF?@I?C=IBEGDD?IBIEG?F?B
@>chr21:9501965-9502114-2
GAAGGTCCTCTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCNTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTAAGG
+
G?DAGADFDABG????BFD@DI?BDGGCIH?BB?AABDIECBCCGCFCDA5DDFDIGGII?EIB?EA?@DEAAAG@DHD@?IAIGHIH?@EAEEE?GBDI
@>chr21:9501965-9502114-3
GAAGGTGCTCAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGAACCAAAAAGAAGTTCCTTGCCCTTAAAAATGAGCATTCCATAATAGACACAGA
+
AC?FC?7FI@GI@GBGAEH"@IHFBF?BDB@BCDF?FCEBBEFCGF0FE?E?C?GICBIFG?FI@HI?HGDBFIIBABF?B@H.@@B@?HBAD@FG@BHC
@>chr21:9501965-9502114-4
GAAGGTCCTCAGCATAATATTAAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAGTTCCTTGCCCTTAAAAATGAGCATTCCATAATAGACACAGA
+
DDFFDDHAICE@EF@FAAFFD-IH?IAI??IA@D?HHDEEECDED?B@FHFBD?FB?ICIH?@CGBI??AFBIDGCADHCBGC0II@ICCAA@B?BEAGE
@>chr21:9501965-9502114-5
GAAGGTCCTCAGCATAATATTGAACTTTCGAAGAACAAGAAGCTTGGACCAAAAAGAAGTTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACAGA
+
AABICGAI@A@F?@BGFEFBACE?EDFA%A@@@BD5ICBEHC?HH?CC??I?DEH@C@G?GBFGGDDC@GCBA@ABBD@IACHGHACA@CCBCC@ACGFD
@>chr21:9501965-9502114-0
GCGGCGTACTGCCTATATTATTTTCTANTTTTTTTCTTCTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTCTGCTCATTTTTAAGGG
+
?AHEIGDHIGIF?AEBICEDCEHG@DD$EGFI?FCFF8E?IGFIBEF@A?FGEEDEFFIIH?GDB?IDCDI?AFIHIAI?GEA&E@?EICF??IB@BDDA
@>chr21:9501965-9502114-1
GCGGCGTACTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTAAGGG
+
F@GBCCDHI?HHGAHEHIIGCIHBC?@GHEBCFFCAFBFCAFAFA?DCC@IBI@@GFH@6EHIHEDFHC@@HDGCFDE?G?@?CFCFHIADCE@ADAABA
@>chr21:9501965-9502114-2
GCGGCGTACTGCCTATATTATTTTCTATTTTNTNTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGNTCATTTTTAAGGG
+
HI?DCHDEBGCDGBEH?@ABFEBIF?FEHFB;D)FIEAFIFADEICC?@?HBCDG@@EAACFD?HIFIC@@GF@IBE?@@GICE?B4FA?FDB@AICBDA
@>chr21:9501965-9502114-3
GCGGCGTACAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAATTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACAGAC
+
ICBAAAG?FCHAFEDDADIBGDAID?FCG@BHDGD@E@FII@G@GBA@EE?DCFCG?HIFHDHCFFDFIDH@GF?AAAAEBIEBEGD@B@IGHICGHFAD
@>chr21:9501965-9502114-4
GCGGCGTACAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAGGAAATTTCTTGCCCTTAAAAATGAGCATACCATAATAGACACAGAC
+
F?DID?FEEFG@AHFG@GEEBGCGEEEIHGI?EBEI?AII@GDA@GIAIE@@C-DCICDA(CFG@HACGCDFIBDFCGAIGA@EFI@HGAAFDIHD?DEF
@>chr21:9501965-9502114-5
GCGGCGTACAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAATTCCTTGCCCTTAAAAATGAGCATACCATAATAGACACAGAC
+
AB@ICCEIGCAEG?CHFCEGGHGCDC@HDEC@ACCBHIDF?IIDAIIFI@I?FDADBD@EDII@CIBIF@@FCIDHGC?CAEHAEDIHFIAAFBDBID?I
@>chr21:9501965-9502114-0
TCAGACGGTAATCTGCCTATATTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTA
+
@?GA?@@FA?FEGEAEGAAADD=CH??FIIABHCBC?FGBACCFE@@FH?@BEADAGH@IGFCBHBII@E?F*@@EGCHDCFFICIBBCCEBG@IC@FIA
@>chr21:9501965-9502114-1
TCAGACGGTAATCTGCCTATATTATTTTCTATTTTTTGTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTA
+
?HHBCECGGEFGABF@HIHDCCDIG?EI?FABGDIF@6CG?EGIBIBFBE?@I?H?@EI@E@F@GH@HAGEIFFI?EDGHEFH?BE@FB?AFIDGA?ECI
@>chr21:9501965-9502114-2
TCAGACGGTAATCTGCCTATANTATTTTCTATTTTTTTTCTACTTAATACATCGTGAGCATCTTCCCATGTCTGTGTCTATTATGGTATGCTCATTTTTA
+
H@@I@@?EBDFDF@EFGDEBE*A?IBHFB@@B@EAHH?GFCFEE@?HHHIDHBDFAG@H?I@B@?IAA?GBD@CDG@AE@FIC?HEIAADHCGGGB@FDF
@>chr21:9501965-9502114-3
TCAGACGGTAATCAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAATTCCTTGCCCTTAAAAATGAGCATACCATAATAGACAC
+
ABDFCDAFAA?IHHCBEHEF@@?CCG?H@A@BCB@@AA@EA?@FFBDDGFH?A@?CH?FCCH?IBC@D@GGGC?ABFEDEDFCIC@@*FGFAHHFHIAIE
@>chr21:9501965-9502114-4
TCAGACGGTAATCAGCATAATATTGAACTTTAGAAGAAAAAGAAGCTTGGACCAAAAAGAAATTCCTTGCCCTTAAAAATGAGCATACCATAATAGACAC
+
GHGHH@BEBFF?B@IBAICCB@@HDG?@E@EGGC@FDB@EAIF@GCCB@??CBBCHGBCDBBHG?FBABEHIA?GAAGA@@AE@IFEIIEHACC@GB@FE
@>chr21:9501965-9502114-5
TCAGACGGTAATCAGCATAATATTGAACTTTAGAAGAAAAAGAAGCNTGGACCAAAAAGAACTTCCTTGCCCTTAAAAATCAGCATACCATAATAGACAC
+
?BHHHIFEBHFE?BH?@FIAGGB?FAA?AA@DFAAGI?DHDEIEDF/A@D@?HFBH@E?@D+FCBCI@@CGDIA?EHEHD:A?DDCDFFCFD@@GCCBH?
@>chr21:9515760-9515895-0
ACCACTGTGTCTGCGGGAAATTGCCCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCACGAAACAAGATCAGCAAAT
+
@BC@E@&@IIBIGABG?E@@D??(BE@BIEA@B?FF?BI?GEE@?IIFH?BAFBF@DA??CIAB?I?ABBFH@@DGACAGAI"?DGIIEA?HG@BDIAEF
@>chr21:9515760-9515895-1
ACCCCTATGTCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGGGGTATCGAGGTTTTATGTGGATCTTTGTGAAGCACAAAACAAGATCAGCAAAT
+
GIG"DG@GADIGGECAID@GC@GDCDF?G?B?H@FDHB@?DDHGHAH?GEFGDDG*GHC?C?@I?FIIDBD@GGCE@BHAHHIGI?EFDFAIHHAB?HGA
@>chr21:9515760-9515895-2
ACCACTTTGTCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGGGTTATCGACGTTTCATGTGGATCTTTGTGAAGCACAAAACAAGATCAGNAAAT
+
GGABGD/AHBD?EI@G@@F@CCBFB@?@HDEGA?HDFCD??@?BAEDG,CIABCFACD@H3EI@?EA@HG@@HHAC@GDCGCFHCA?HIEHA@IG>BHAI
@>chr21:9515760-9515895-3
ACCACTATGTCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTNTGTGCTTCACAAAGATCCACATAGAACG
+
DHGDCHCGFID@C@E?HAE<BCC?BHAAD?BFCIAF?DF@FBHEHF?HH@FCC@FBGEGFC?FI@IGHBBB,BBBIFDF???FAE@G?II?H(EC;CCEA
@>chr21:9515760-9515895-4
ACCACTATGTCAGCCTGAACCAACTTAGTCAGCTTTCATTATTAGTTTCTTTATGATTTGCTGATCTTGTTTTGTGCTTCACAAAGATCCACATAAACCG
+
@BAA@BC@FGGFDEDBE@FABFI2B=IHDBFAECIEICBECAA*@@CCHGIHFBEGICICBEEGAFADCCDHFDFDFAFEBGCG@CIGAFBBAGG??"EA
@>chr21:9515760-9515895-5
ACCACTATGGCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTGTGCTTCACAAAGATCCNCATAAAACG
+
GGFBD?B@?9BE@IBDC@GGE@GF=EH@FFIC?HFIE?A?FFFE@CAGC?A@GDHFHDFIIDBG@EIEAF?CE@AFCCA?GHGDAHEECA'FEAEAG?FF
@>chr21:9515760-9515895-0
CTCATACCACGNTGCGGGAAATTGACCAACTGCATGTGAACTACTGGGGGTATCGACGGTTTATGTGGATCTTTGTGAAGCACAAAACAAGATCAGCAAA
+
BAFCB?CG??G3G?EIC@?CGEDCDHAHFCA?F?"BDBIHGFGFFHFACIDFFDH@D?1?FIBFC@B?DBDIAA@AIIACACH?A?IIIFIFC!@GFC@C
@>chr21:9515760-9515895-1
CTCATACCACGCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGACGNACAAAACAAGATCAGCAAA
+
HG?BCF?GCGIDHEBACDHC@BDD@@BAH?@@?C?CDGH@FHDEDCDDCIH@B@@CBDD@EFCAB?IFICDIC??AC@=A3@BGHBHE@@@@??FI@CEH
@>chr21:9515760-9515895-2
CTCATACCACGCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCACAAAACAAGATCAGCAAA
+
CAH?DAAFABBF??DDGIEABAICDB?EIDFBABD?BHAFCHEICB?GI@FBIHAFDFGDBIHIHAEBIEFIHBDDBCBGE@C@FHFBIG?AF@BBHIGI
@>chr21:9515760-9515895-3
CTCATACCACGCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTGTGCTTCAAAAAGATCCACATGAAAC
+
CFCEA?@DDCAHDFBAHDA?@B?BFDE?A?BDDCDBCAIBCIDIG@??CEAHB?FG@HHHHH?BDA?FAC@FHFE@GI?CC@'ADE?DGCFAFIF%CIIC
@>chr21:9515760-9515895-4
CTCATACCACGCAGCCTGAACGAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTGTGCTTCACAAAGATCCACATAAAAC
+
AIFBCHBHAACF?GGFG@BFF3@DF@?BAIAEEF?CFI@G@AC@?IEIECCGIGEFI@IB@FEGFDIAIFEFCEIIDBBDCEGHCI@HEGFHIA@EIBIC
@>chr21:9515760-9515895-5
CTCATACCACGCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTCGTTTTGTGCTTCACAAAGATCCACATAAAAC
+
CEGAICIBF@?FAAICIBCFHB?DCBGHFCGEF@AF@I?GE@E?EBBFHHGBABG@CB@AGAFEGGGF%F@EBIDEGFFEIFDH?C@HFAFB@GIEGCDI
@>chr21:9515760-9515895-0
GAAGGTCCTCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCAGAAAACAAGATCAGCAAATC
+
EB@D?IAGBIFIBH?BIGH@FB@BFCABH?II@EG@IEAAB@DGAEDHCBD?AF?AHHADGEDAAAI@EAGIIE@HBFHB?CAH@A??BAAE?BIB@@DH
@>chr21:9515760-9515895-1
GAAGGTCCTCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCACAAAACAAGATCCGCAAATC
+
BCEIGCAIIA@DIEID??G@HFHF?FBCFHADFCDBFHHI@IAI@CDGEBDBEHC@CIFHAEGBEIGG?AFDIB@H?GDEEHDDGFHFICHF;BEF@DHE
@>chr21:9515760-9515895-2
GAAGGTCCTCTGCGGGAANTTGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCACAAAACAAGATCAGCAAATC
+
AIEIEGHGDG@BE?@EHI:@CIF?AHDD@H?HAIHAAB@HFBCDH@@?@AI@EDI@GHB@?F@B@BAFHA??HBCDHHAEHHCFGDHABFBAHGBCAIEC
@>chr21:9515760-9515895-3
GAAGGTCCTCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTGTGCTTCACAAGGATCCACATAAAACGT
+
GEDHAIEIHEHDCGBGA?E?C@BFCAHEIEHE@GII@GDCAEFDD3AGGBED@FCBICA@EEFIFIFEI@B@@E?HCD?IIG?$DI@BF?IIACH?FDED
@>chr21:9515760-9515895-4
GAAGGTCCTCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTCTGCTTCACAAAGATCCNCATAAAACGT
+
HA@FAHCH@H?HG@EHGE?FHFCGDIGCBDC@AGAHACGBACDABDDAIIEHG@EF?FHI?CEDDADE??BGFE@AEDE?ABAGEFEDD&DDDAEGAG@G
@>chr21:9515760-9515895-5
GAAGGTCCTCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTCTGCTTCACAAAGATCCACATAAAACGT
+
DHDCEC?CGAACGDCC@GHCCHFGDHHCG?F?DGBCAEBA@?FEEI?FD?HC@FHD@B?B@GI?HFI?FEE@IBHEDAGA?ACAEGDEDB@@CGEAAIGF
@>chr21:9515760-9515895-0
GCGGCGTGCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGNGAAGCAGAAAACAAGATCAGCAAATCA
+
BHIBEFA*EB??DD?GHEAFF?E@BFF?@CHBGIC?C@?CHAHCADHAEGDDID?@B?CDABBIGA@GIHEI0FA?GGFHGIGHHE?ICDAII?GCA@BB
@>chr21:9515760-9515895-1
GCGGCGTACTGGGGGAAATTGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCAGAAAACAAGATCAGCAAATCA
+
ABHFA?BHGBC0@@A?HBHDGAEB?AEIE@HBF?FFHIEICE?@@EBBID@H?EEDFBHIFA?HCC?IIAA?DCAE?@?GGIE?@IFFBCBB?IHE?@BA
@>chr21:9515760-9515895-2
GCGGCGTACTGCGGGAAATGGACCAACTGCAAGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGGAGAAAACAAGNTCAGCAAATCA
+
GBAFCDGEE?EAGCGDHFB$GAFC?H"BA?IBF@?H@FAAAHHGFHAGGDCGGA@CICE@HB?E@IDEGCIBIICHD,GGFGFGD?DC%AB@C?HCEBH?
@>chr21:9515760-9515895-3
GCGCCGTACAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTCTGCTTCACAAAGATCCACATACAACGTC
+
HC6!@IEEGIAG@HCGHC@AG@A@AFGCGHGGGBCCAFAGEAC@DHGFBHF?EHBCHBGCI?G??HI@?AFC@IDGGHIBEAGCAGCIEHHII:@IFHC@
@>chr21:9515760-9515895-4
GTGGCGTACAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTCTGCTTCACAAAGATCCACATAAAACGTC
+
@(?BB?C@I@EHDBGEDH?DDFEFGIADI@GGG@GCF@EIEDH??GGHBEBFH@E@FIEGGGHIAB@H?GIAFE?@CH?FHGHF@@CCC@FHFDGBDA@D
@>chr21:9515760-9515895-5
GCGGCGTACAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTATGCTTCACAAAGATCCACATAACACGTC
+
IGEF?CF?HABAB?IBGAHH?CED@?@A?AHGIBCDFEGGAHG@CCAB?GCCEEC?IAGIEAGCA?HIDE@>CBAC@@BDEDGFIAE@HDIGDG:II?EB
@>chr21:9515760-9515895-0
TCATACCGTAATCTGCGGGAAATTGACCAACTGCAAGTGAACTACTGGCGGTATCGACGTTTTATGTGGATCTTTGTGAAGCAGAAAACAAGATCAGCAA
+
?EC<@G;BCABED?FFIGEAHAAGFIEDHFDHCFCIABFDFHCFFIBH8@FFIE@HHBFBCAHHH@CAEHFA?BD@AB?IEC@AHCC@?H?CF?@F@CC@
@>chr21:9515760-9515895-1
TCAGACGGTAATCTGCGGGAAATTGACCAACTGCATGTGAACTACTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCACAAAACAAGATCAGCAA
+
GEI?HCIADEDEC?EIGGIICC??DFEFFIGFDAF,BHEEDFCD@@E?A@CC@ICHGCFDD?@BEIBB?BI?BIBF?EDHGFB+BC@BIIH@AGDGG?HH
@>chr21:9515760-9515895-2
TCAGACGGTAATCTGCGGGAAATTGACCAACTGCAAGTGCACTNCTGGGGGTATCGACGTTTTATGTGGATCTTTGTGAAGCAGAAAACAAGATCAGCAA
+
HDAH%A?B@BDAH@A@CI?GIDC@DIIBBD?AGCHBHE@5CHC'G@GDAIAEIC@CCDF@FEIACHG@?IEAEDBDACDBCG@GHHDCAGBHACFBFEHH
@>chr21:9515760-9515895-3
TCAGACGGTAATCAGCCNGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCNTGTTTTCGGCTTCACAAAGATCCACATAAAA
+
AFI?CDDFH@FE?HAEF0ED@GHEEBGAGEF@DIBE@FFHD?AADGCHE@IA?GAGA@@IF?@CBEGI.DCCEEAH6DAH@@A@GIBF?HCIBABIFADC
@>chr21:9515760-9515895-4
TCAGACGGTAATCAGCCTGAACCAACNAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTCTGCTTCACAAAGATCCACATAAAA
+
E?HF?DB?ADABA@ED@CBEFHGDIG9?BEFFFC@IAGBFD?HHFC@AC?CBHBCAGIHD?CBBI@@G@GFDCIBAGHEEHDCGF?CC?CHF?GDHHGE?
@>chr21:9515760-9515895-5
TCAGACGGCAATCAGCCTGAACCAACTAAGTCAGCTTTCATTATTTGTTTCTTTATGATTTGCTGATCTTGTTTTCTGCTTCACAAAGATCCACATAAAA
+
G?B?F@IE3FDBIEEIEAIDADAAF@HIA@DAGEB@AEHFID:FEBGGAF@CEGCHGBBAEEDBCDAEAG?C@AHAG4IBGFFBIBIBF@IAGGACHDC@
@>chr21:9528546-9528614-0
ACCACTATGTCAGCTGGAGATCTGAGAACTGNGAGACTGCCTCCTCAAGTGGGTCCCTGACCCCTGACCCCCGAGCAGAGATCGGAAGATNGAAAAAAAA
+
GICCD@ICABF?@FBC?GEIEE@DFHHEFGA#"?CCDHHFBCDHGEIGABEEE?D@BG?@@FHFD?BAC@IIEHA?AE@B@@?FAD?(D%!GE@A?B?CE
@>chr21:9528546-9528614-1
ACCACTATGTCAGCTGGAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCCTGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAAA
+
EGBB?HCBFIGD@CGCEGCABCEEECDGFHGF@GG@D?HEECDDIECCI?B@CDA?BBFCCCDDBDAE?A@BG@2?IGBIECAHHGAHCIBIFB@A?ID@
@>chr21:9528546-9528614-2
ACCACTATGTCAGCTGGAGATCTCAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCCTGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAAA
+
CFB?BA@@BIDFAIDBFGE?IDH;DHCGIFIFHHIC@BAFIBDECFEF@FCCABDDIDH?F?I@BBABA?@HAFHII?A?FEDE?GGGBBACGI@HG?FB
@>chr21:9528546-9528614-3
ACCACTATGTCTGCTCGGGGGTCAGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAA
+
FA@GHBCGFAFAAA@@BAAEGIIF@EHICAAGHCIFEFEDIIEI@I?CG@CAC?CDGFGDHBEID@I@AAGGFHGIHHHAGBDEAFCEI@E?IIB@EE@H
@>chr21:9528546-9528614-4
ACCACTATGTCTGCTCGGGGGTCAGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCTAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAA
+
HIHCCABB?A?DDBFEBDGFBGDEDABDAFH@AADBA@?HHEGEFFFHF@HHD@ECD7D@G?DDAGF??IF?FDAB@DIBDGE@HADAEBD@FGCAFEI@
@>chr21:9528546-9528614-5
ACCACTATGTCTGCTCGGGGGTCAGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAA
+
B@DGD@BB@GIHHEI?HGECEDF@CCCEFDABD?@CI?IBCBACA@@HEABEBDCGCAEEA?HF@?GEEGCEFC?GC?C@?BAECGEGACCE@IBH?@HD
@>chr21:9528546-9528614-0
CTCATACCACGCAGCTGGAGATCTGAGAACTGGCANACTGCCTCCTCAAGTGGGTCCCTGACCCCGGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAA
+
?BBBCBH?I@AGHE?@HBHHFFIEIACBHACEADG9@CCB??@?E@FCEDHCAIICDGHHGIB?HFGGEIFGFGCFGAHGDACGEFAIHHCHACBICHAB
@>chr21:9528546-9528614-1
CTCATACCACGCAGCTGGAGATCTGAGATCTGGCAGACTGCCTCCTCATGTGGGTCCCTGACCCCGGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAA
+
FGDDBFIIIEIEIBDGF?HBIICBA@DA=IEIFCAFBE?CAFAB?DEC<B?@EG@EGDHH?AI?HC@H@@@BFCHFFBGCBAA?GDHBF?CHHFICIEEE
@>chr21:9528546-9528614-2
CTCATACCACGCAGCTGTAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCCGGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAA
+
HDGAEEGG@HDIAIGGH;@DAHGAGDIDAIHAFAHGEAGCFFF?F?BDBICHCEDBB:FEAIADFICDBG?BGB@BBI?EC@A@D?AGIHHA?HAB@AIA
@>chr21:9528546-9528614-3
CTCATACCACGCTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAA
+
IGGGIBICIHFCHAIHHI@CDCFHCEIGG@GAEI??GFIFE@FCEG?ABAA@@DG@B??F@F?GAC?E?AEIDFHECHFGFBB?IFAFHBC@CEADAFH@
@>chr21:9528546-9528614-4
CTCATACCACGCTGCTCGGGGGTCCGGGGTCAGGGACCCTCCTGAGGCGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAA
+
A@GDDDIIF@IFCEBABEH@@EI??DADBGI?HC?CFCB/E#HCIGG8HGEFHGDDFDF5CF@A@IAIDDAAECH@IBCF?GBE?B@AGFI@@I@FCHDI
@>chr21:9528546-9528614-5
CTCATACCACGCTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAATAAAA
+
EGECG?BGIBB??IHHGBACGGAACE?CF@CFICEI@ECA@BEEDADAICDCDIDBF@CBGBICAHBHCFEG@IHCIGHEFIAIBE?@HDCB@EC4HDHC
@>chr21:9528546-9528614-0
GAAGGTCCTCAGCTGGAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCCGGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
?@EECCD?GDA@A@BEFCDIGBCHICFF@B@GF?IIG@GIIGIC?ID?AFAFI??IBDD?FIHHGDBAFDCICEECHIABFII@IHFFEHHA?CFDIEHE
@>chr21:9528546-9528614-1
GAAGGTCCTCAGCTGGAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCCGGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
HF@HA@DIFIAFF@AC@CD@HFAFHAG?HCCBIAEFGH@?HBDGHI?IGEFFDEA@B?FABAHC6IBEECHIHEHH?C?GGCDFAG?IEBHF@A5EGFEB
@>chr21:9528546-9528614-2
GAAGGTCCTCAGCTGGAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCCGGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
F?EFBDDF?@GDE@DIII?EGEF?GAFDGIC@CC@B<CCC@FEDGBEADGIFIDCGEIBHIIECBFEAHDDI?HC?D@ADDHCDHIBFGBAFIGDICHIB
@>chr21:9528546-9528614-3
GAAGGTCCTCTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTGCAGCTGAGTTCGGAAGAGCGAAAAAAAAA
+
DBHCHIHG@GD@IBHFEHA??H?@C?EH?FI?HD@C@??CHG?GFHHEGIBA?CFHICADF?CEDAEBHE#A@FBE@IH"?ADGFCG@CDHDE?EHHBGE
@>chr21:9528546-9528614-4
GAAGGTCCTCTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
I?BBABFAGDFCA?DIAA?IHHAIFIDBIHHHCDBI?@EE?IADCIAGHEHFBGFAFDCIBCEC@AIHFFFIGBB@AFGIHFAEBADIDGHCGDBFIIE?
@>chr21:9528546-9528614-5
GAAGGTCCTCTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGACATCGGAAGAGCGAAAAAAAAA
+
D@EH@CCI@D@?I@FGFGCF??HBEEHAEBCD@I??HBEIIDBBEEDADDA@GAIAEDHBCAEFHIH?FG@DIFGFGA6GDBGGDFAHG@DDBGFACFI@
@>chr21:9528546-9528614-0
GCGCCGTACAGCTGGAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCCGGAGCCCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
CF?)BFFFDEFGGA@?BE@AABEI@HBIADGACAI?B@@BDFDHADHFBCCA?DHEFHG@E@GHE+GB?HA?GAEGBA?H?HFAA@@D?DGH@FBIDB@?
@>chr21:9528546-9528614-1
GCGGCGTACAGCTGGAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGACGCCGGACCCCCGAGCAGAGATAGGATGAGCGAAAAAAAAAA
+
@IIDDDHGEFA?E@IHDC???C??IGEEAC?CIIDFCCECAF?IFGHCAHABHFFA/H?%H@@DEBDIEG@CFI?@I?FF;BHB=@BBHACIGCBBCDDI
@>chr21:9528546-9528614-2
GCGGCGTACAGCTGGAGATCTGAGAACTGGCAGACTGCCGCCTCAAGTGGGTCCCTGACCCCGGACCCCCGAGCAGAGATCGGAAGANCGAAAAAAAAAA
+
IAGIIGB@HH@?HICDBEE@?H?G?HDG?@FEDAAEEHI6GGDBGD?CI?D??HAH@HA?ICC@?DGGGBAGFEHEAF@BICCDFDD3A@GHE?BHGC1I
@>chr21:9528546-9528614-3
GCGGCGTACTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGTTCNCCAGCTGAGATCGGAAGAGCGAAAACAAAAA
+
GAG@??EBEGIIHF?@B?IEIBBAI?IFHFGA:BEGAFFDAEI?FBGBFFACFC@IBCDCHGE@E7@@3?BF?FEB@A?HI?@HFD@CAF?DGG9DBCHD
@>chr21:9528546-9528614-4
GCGGCGTACTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
DDBF??DBH?ACFFDFEGD@DHFCCIA?HDB??@CAF?GCGIH@BAHEFI?IF@@DACG??E?IIDC?CDG?IHI@FAFHC?H@A@ABC?IHHGIFFIAE
@>chr21:9528546-9528614-5
GCGGCGTACTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATNTCCAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
IDECEA@BIFDDFEDHDCG?F@IDBEHHE?IDG?FB?FHDICDGEC?@?G@DFE?@FFEF?AEHG?E>GEGFHED?DEGGGBGBA?G?D?HD?@GA?ACH
@>chr21:9528546-9528614-0
TCAGCCGGTAATCAGCTGGAGATCTGAGAACTGGTAGACTGCCTCCTCAAGTGGGTCCCTGACCCAGGACCCCCGAGCAGCGATCGGAAGCGCGAAAAAA
+
@IIF;HI@CBGFGI?FDI?AGHDH@EAH?GDIIF9IGICE??FEFEECG@EDEGGAD?C?EBDBI7?@GBBHFHFCEEDH$GF?HFIBHC%BD@A@?A)I
@>chr21:9528546-9528614-1
TCAGACGGTAATCAGCTGGAGATCTGAGAACTGGCAGACTGCCTCCTCAAGTGGGTCCCTGGCCCCTGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAA
+
ED@DF?EGHCHC@?BI?GBAGDADIEEE@C@GEF?ADA@AABFDEF@IGD@HAE?BDBHAI2B@CAIGGCFF@HIHE@@HGB@ICGGEBEEBHF?@DE?G
@>chr21:9528546-9528614-2
TCAGACGGTAATCAGCTGGAGATCTGAGAACTGGCNGACTGCCTCCTCAAGTGGGTCCCTGACCCCTGACTCCCGAGCAGAGATCGGAAGAGCGAAAAAA
+
ECICIF@EB?@CFDA@GH@EE?@?ICFAFCBCCIF)GACBEEB?GDCFHFFAHEBCDB@IEF@B?HA?AC:DDBBBEDGHHFCIDI@HCC?EI@HHEI@I
@>chr21:9528546-9528614-3
TCAGACGGTAATCTGCTCGGGGGTCAGGGGTCCGGGACCCACTTGAGGAGGCAGTCTGCCAGTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAA
+
A@I@?AGFEIEGHHGHGAFEIFBD?DHBEIFC.??BFEE@AI?GFAHECG@DIG@?EFC@G@B??EAEIIAG?GI@BCHDF?EE?FI??E@D?IBGEHHB
@>chr21:9528546-9528614-4
TCAGACNGTAATCTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAAGCAGTCTGCCAGTTCTCAGATTTCCAGCTGAGATCGGAAGAGCGAAAAAA
+
FB?F@C&DFAHD@E?@AHI@EGHIGBGBDGEC@@FF?BBGDGHID@G@F$I?BIGF@F@BI?BF@AEICDH6H@BCFHHH@BGEA!ECD?FGACHE??DB
@>chr21:9528546-9528614-5
TCAGACGGTAATCTGCTCGGGGGTCCGGGGTCAGGGACCCACTTGAGGAGGCAGTCAGCCAGTTATCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAA
+
?FBIFBCDEAHHHAAA@C?C?DFDHBB?@AHI@GHHCEHAD@H?CHBABDHBAI@@$BACFI?I:?BGGBG?C??@HC6BBFB@HCDDE@HAA?ACA?BG
@>chr21:9528611-9528711-0
ACCACTATGTCCGCCTATCTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACTAT
+
HADCEIEBDEFCED@G@*CADAG?@GB@CHA?A?AFD??GFEDFADHBBGDFE?DI?DDFE@IBBIHHCGAHG@ICB@BIEGBFD?DHIDE@CEA@B5G@
@>chr21:9528611-9528711-1
ACCACTATGTCCGCCTAACTGGGNGGCACCCCCCAGTNGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTGCAGAGGAACGAT
+
CDHEAEGAGCDEEGGIH@FCIA?+BHF?GIAI@IA@F6?HEDIC?DD?AIAIBF??GBFHBGCECFDEAFG@BAFA?HCHCDCEID@$H@DDBG??H?ED
@>chr21:9528611-9528711-2
ACCACTATGTCCGCCTAACTGGGAGGCACCCCCCAGTAGGGGTAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGAT
+
@B?ABHEBCHHFBDHEIHAHGHEBDGIFA@EDCHB@GAAFD@%IEGEADAFBI?BEBGBIHE@CFDFB?C@BBF?DCBI@F@CE?AIABCDDGD?GDCIB
@>chr21:9528611-9528711-3
ACCACTATGTCTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTNTGAGGTNTCAGTCTGCCCCTACTGGGGGGTACCTCCC
+
@HEF@IDAAGBFA?IEBCC@FAFCHIDA?B@EEAFEHADDFBFE?@BICAEC@CD?AE?DHD(?@@CDE5E?BAD?AHAF@DEDFDAEHBDIF-G?CDF@
@>chr21:9528611-9528711-4
ACCACTATGTCTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGCGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCCC
+
EB@BGEA@EFCHE@GEI?IBCGCHCHF4AHCEHHHD@CGHGEABDCD+H@E@CDAIIIFBDDAD?CACD@FEBCBI?@?HEFADCDHI@?@HBEGB??CD
@>chr21:9528611-9528711-5
ACCACTATGTCTGCTGTCNGATCGTTCCTCGGGAAGTTTTGTCTCAGAGGNTTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCCC
+
HAEABABADCH?GI@@HI+?@IAA@GCFFA-E?ECFGH?FIH?@E?BEHA0ACEE@FF?AID?DDFGGADGGCE?AIDD@EFDFABHFECD?HIBDDEBE
@>chr21:9528611-9528711-0
CTCATACAACGTCGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCACTGAGACAAAACTTCCAGAGGAACGA
+
IEIDHDF"?AD*AFBDIHDBDFEECHB?IHFIGDGDECAHBGC@EGHE?BGHEA?D@ADB@?ICGGH1=GBEH#HIDBC?IEC6BFDAIBFHCECCDGFD
@>chr21:9528611-9528711-1
CTCATACCACGCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGA
+
?DFCCIAHEAFGAA@FHFF?DCAAIEA?FEFF@E?@I@?H@??FICIBIHF@A@?CEB?FG?ADFCECDE/G?HE@CEHAGBG@GF@?BGC?BADGBC?F
@>chr21:9528611-9528711-2
CTCATACCACGCTGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGA
+
?DIGDGI@BHDF>BEIADI??AC?DDAIGAA@*@@EGBDGD?HAHF@IGHIADGIACDID@?DD?BBCBAFHEHI@DBHHD?I?E@AEBIBGB?DBDHCE
@>chr21:9528611-9528711-3
CTCATACCACGCTGCTGTCCAATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCC
+
BIHFADACGIIEH@?EGCB0!EFC?GEFAFHFGFD?F?G@GEIGBEG?BGECICIHHEGF?FAAICG??F@?B@FCAEIFBHFHCEBH@HAH@DBCHFI@
@>chr21:9528611-9528711-4
CTCATACCACGCTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATAACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCC
+
GFFII@?IB?GH@AB?B@GEEBCII?IIFFEBEB@DHA@?EFDHIGIICIIFA7AE?HIIICACDED@)HFIF@BEFEDEFHGCEHEEC@?@?CBC@BGB
@>chr21:9528611-9528711-5
CTCATACCACGCTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCC
+
?IDGAHIBHGCDBFAEFGGCHIGA?GEBA@FF@BGHCCDDD?IIAFBFIEGAHDE?@@ACFBBHFHAIIGFCEGAE@?F?@FEDHHCAFF@AFAHACCBE
@>chr21:9528611-9528711-0
GAAGGTCCTCCGCCTAACTGCGAGGCANCCCCCAGTAGNGGCAGACTNACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGATC
+
@DH@FB@DEIG?DABFE@G?:EFCD??6E?G?HGGBH@"@CEFEEED'A?CE?EGHCF@ICB@HCF?FEB@DAGAHHE@?FFCDHAEHFBEAE?H?BHC@
@>chr21:9528611-9528711-1
GAAGGTCCTCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGANTGACACCTCACACAGTGGGTAATCNTCTGAGACAAAACTTCCAGAGGATCGATC
+
BFEAE?EHHGBDEA@BGC@ABGGGEGDCCIB?CEHFAEIH@@DAD-CCC??DE@AHAAD@HDIDBBID?@'GCEIC@HD?GGIEDFHIDBG??D"IGHHA
@>chr21:9528611-9528711-2
GAAGGTCCTCAGCCTAACTGGGCGGCACCCCCCAGNAAGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGATC
+
ECEGDEFEE?EABHDA?@IIBH(GHBDHDFIHHEH0I$?ICCA?EAGCF?@CCBI??DCGGBCEAGFDIAICFBEICDE?DIBA?ICDC?FBBI@IHFDF
@>chr21:9528611-9528711-3
GAAGGTCCNCTGCTGTCTGATCGTTCCNCTGGAAGTGTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCGACTGGGGGGTGCCTCCCA
+
HB?G@?H?+G?BIDG@?D?G@DCA@BD*AGCEFAIE(GFH@FEBIHGIECIEBFE@BI@C??AHEFADAACH???F?ABA?#FG?EIABCIHIHCHFHG?
@>chr21:9528611-9528711-4
GTNGGTCCTCTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCCCA
+
?+&IDEBH?@GG?CHG?H@EFHI?IAH?A?BHC?IFG@FBD??A@BBEIDAGHFFD@FG@?BCFBCFFGDBB?IIAB??AHIFCABDAFA?DECC@CACI
@>chr21:9528611-9528711-5
GAAGGTCCTCTGCTCTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCACTCTGCCCCTACTGGGGGGTGCCTCCCA
+
IIEFFDGCCB@CGF;?IE?BCB?CE?IF?GDB@DADBHGCA@?EEE?GBFEDIHGH?G@HH?EGBGA@EHGC4=CGCHDGFHG??EGDG@F@AG@BDCIH
@>chr21:9528611-9528711-0
GCGGCGTACCGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGATCA
+
?G@F@GAI@@EBEDDCCGED@HAHIBFBFGA@EGHFDABB?F?DDEGHBBGFCI?GIGAEGCEHDHIEDA@GDGB@AFEE?IGCBGD@?A?AHAEBD?BA
@>chr21:9528611-9528711-1
GCGGCGTACCGCCTAACTGGGCGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGATCA
+
FE?BB??B?DCAGHB@@HGBE<E@CFB?FF@CGEB???BAHHI?AGIDA@EFHHEFFDG@?@CGHFACABBEG?GAHID@GCGF@?HAAIBEAA@@G@GC
@>chr21:9528611-9528711-2
GCGGCGTACCGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACGATCA
+
D@?GFIHIC?FE?BCGBIAGDDG?BCAFDIGCA@EGAAEC@HIG@DG@?HEHDBGIADGEFAI@E?D@CHIFD@@EDGCAFAECF??AEI??FIGAHB@D
@>chr21:9528611-9528711-3
GCGGCGTACTGCTGTCTGATCGTTCCTCTTGAAGTTTTGTCTCAGAGGATTACCCTCTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCCCAG
+
G@D?IBECAAHI?@?IFED@CECBIAGEH1A@D?EDDBBDDHF?GIDAAIEDGEC7BC@DF@HFFEEF?@EDDG?GAEGBIDIAG?BFGBGA?HIGE?GF
@>chr21:9528611-9528711-4
GCGGCGTACTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCGACTGTGTGAGGTGTCAGTCTGNCCCTACTGGGGGGTGCCTCCCAG
+
CC@CACBHC?DE?CDAFF?HID@?@FEIAEIHBG@BCHHFEDAFAIDEFGCFCG"AD?F@ICCDGCIICBDF@EFD;BIIDD@DFI?F@IFE?EECE?DC
@>chr21:9528611-9528711-5
GCGGCGTACTGCTGTCTGTTCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTCCCAG
+
@GAAI?E@@@GIAF?@FC-GCFAIEEIF@AG?DIDBIFCAH@FF@FGHGGEB@ED?CCDEIHH?CCID@A@EHFC?@?ABDICA@DGBCGGIE@DAFAAD
@>chr21:9528611-9528711-0
TCAGACGGTAATCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACG
+
@FI@C@@@BI?CAG@ABBG?DGADDC@@EBE@GCBAIHI?GIGEFBCGE@?H?GI@AHIE??ICHC?HA?FIDHGC@DE?CGHDEGBFEFHHGGBFAD?G
@>chr21:9528611-9528711-1
TCAGACGGTAATCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGTAATCCTCTGAGACAAAACTTCCAGAGGAACG
+
EBF??HAD)?IBH@DFFIAIE?IAEIAFC@IBEDIFHFBBGHAIHBAGGCIAH?I@HGIBGIHGGGIGAC?CC@@DCBGHGF?GIG?I?HHGE?IDDEBE
@>chr21:9528611-9528711-2
TCAAACGGTAATCAGCCTAACTGGGAGGCACCCCCCAGTAGGGGCAGACTGACACCTCACACAGTGGGNAATCCTCTGAGACAAAACTTCCAGAGGAACG
+
HDI"GEEAFCCIBHCA?IDE?AFGBDIDGCBIAHBGGCBFEAD?A??CFBA?GEC@?A??@F@HGE?G6CBE?GCID@@C@CF?HHE@AIE@EBBIFA@C
@>chr21:9528611-9528711-3
TCAGACGGTAATCTGCTGTCTCATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTC
+
I?EBIHIAIIBD?C?HAHCEH9GBIFGEFADHDIGGHECIHFIBFFEFEHDGBE@BGD@GIGCEFI?DCGHHBI?FE@ICCDGHEICDHDIFBFH@@CFC
@>chr21:9528611-9528711-4
TCAGACGGTAATCTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGTGCCTC
+
CG@H@HBBAB?@HAFADDEC@DG@DIABECGAB?I?DHAFI?@GG@GEED?FC?IH?BI@HE@@BFIIABEDCCGCHFCAG@ACFDDGBHDBFG@@EGA?
@>chr21:9528611-9528711-5
TCAGACGGTAATCTGCTGTCTGATCGTTCCTCTGGAAGTTTTGTCTCAGAGGATTACCCACTGTGTGAGGTGTCAGTCTGCCCCTACTTGGGGGTGCCTC
+
DGHIFA?D?@CGGH@AAH?EG?C??CE?BGHA@I??G@CDD@AFC@CIEEDAEDIBGA@?GH@BHDHC@GDEF?G?BFBGAIHAIHGA5A?FBFGBCCBE
@>chr21:9528751-9528814-0
ACCACTATGTCTGCTGGTACCCAGGCAAACAGCGTCTGGAGTGGACCTCTAACAAACTCCAACAGATCTGCAGAGATAGGAAGAGAGAAAAAAAAAAAAA
+
BHDDDBBGEFD@AAAHGI?HCCA?FBCBEDIIEDC?HEF?HCHIGDB@C??EH?CEHFGBAGG@?CF?CFGADBDBF'@FCBCAE"@GGDBDDHHGFBFB
@>chr21:9528751-9528814-1
ACCACTATGTCTCCTGGTACCCAGGCAAACAGCGTCTGGAGAGGACCTCTAACAAACTCCAACAGACCTGCAGAGATCGGATGAGCGAAAAAAAAAAAAA
+
HEDEIC@CBBDG#B?CIICE@@EHBEF?EEBICB@IHDEAG7HIHDDDEEHGFEDE@A@G@AH?DBHB@DC@D?BCBGHBH3DDFEBBH@AFAGEAGC?I
@>chr21:9528751-9528814-2
ACCACTATGTCTGCTGGTACCCAGGCAAACAGCGTCTGGAGTGGACCTCTAACAAACTCCAACAGACCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAT
+
EFGFAFFBAFHECFFHA@HGEG?HFEIEID@D<H@B?@GBDAB?DDBEAFAFFAHCII?GI?FIF?A??HGDHCEB?FBFFBDIGE@AH@DCIDECG@D'
@>chr21:9528751-9528814-3
ACCACTATGTCTGCAGGTCTGTTGGAGTTCGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGAGATCGGAAGAGCGAAAACAAAAAAAA
+
@ADI?GIBE@CBAHEDE@IBCIEIAI?I?,?BAGDBH9@HBAH?DEACH@AG@?DBB@GBBIFBBDEGHADED?BEF?GGBBBCECC@HEC%@DEADGGC
@>chr21:9528751-9528814-4
ACCACTATGTCTGCAGATCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGGGATCGGAAGAGCGAAAAAAAAAAAAA
+
IAFCHBEGF@"BC?AAAEH@HCECCH?AB??BB?DDIFADGDHID?ABDC@BBIGB?DFI@?CEHFICFEGHA9E?BG@@CGIB?DDFADCG?HH?BDFG
@>chr21:9528751-9528814-5
ACCACGATGTCTGCAGATCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGAGATCNGAAGAGCGAAAAAAAAAAAAA
+
IF@GA:GACDGEAA@EFAAD?GA?AE@FFBEHEDEF@D@AFEBBI@BDACG?EHFHACD@AE?GB@AFFDGBEBA@@A$ID??@A?CDI?CDEEA@AHE?
@>chr21:9528751-9528814-0
CTCANACCACGCTGCTGGTACCCAGGGAAACAGCGTCTGGAGTGGACCTCTAACAAACTCCAACAGACCTGCAGATATCGGAAGAGCGAATAAAAAAAAA
+
ACED>@?BADE@BDHBAD?I@DIB@F5?CGD@AEAAAIGFFGICEFHFBGBFDEHGFBGFA@IGAB?@EDA@GEF-B@@?GB@IDEEBFB6BBHB?GIBC
@>chr21:9528751-9528814-1
CTCATACCACGCTGCTGGTACCCAAGCAAACAGCGTCTGGAGTGGACGTCTAACAAACTCCAACAGACCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
HBI@?IA@CA?GEBBAD@GBIFBF7EG@BFIE?F?@H@CABCBBEHG9BIGGCBEACBGBD@@ABIHBGACDCACHEBHH?DBHDCI?AFHEF?G?FE@@
@>chr21:9528751-9528814-2
CTCATACCACGCTGCTGGTACCCAGGCAAACAGCGTCTGGAGTGGACCTCTAACAAACTACAACAGACCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
F?FAHDEHGFCIEACFABC?FAG@DAEFI@AEGHICBHEHAIIF?FE@@FGDGE@IECB+GDDIH@DDIHDD@?D?FBBIF?IDEHFAG?HCBFBH?FEB
@>chr21:9528751-9528814-3
CTCATACCACGCTGCAGGTCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGAGATCGGAAGAGCGAAANAAAAAAAA
+
ABFIIDHF?BAAFDG@DHEBAFDABDIBDGA?G?DCBCACI?D??EGIAEBG@@GB@?CC?DEHH@@BBFIB@GG?G?ECGEBCCE?CD@C%AHBDCGFA
@>chr21:9528751-9528814-4
CTCATACCACACTGCAGGTCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCGTGGGTACCAGCAGGGATCGGAAGAGCGAAACAAAAAAAA
+
FEFBDDGGDC<@?GEDDI@H@?IA@CAIHICHFII@HIFFEDIAIIC?@FCI@AAHF?@B*GD?CC@IBEDBB?-GC?HEIAA@AC?ADDD*CDGEC@@E
@>chr21:9528751-9528814-5
CTCATACCACGCTGCAGGTCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGTCTGGGTACCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
CAHHDIDB?G@IA??D@DFIB@?EF@CBAFEIBD@HF@@FB?GDHFCE??FGCHICDG?-CEAAGEIHHGFBCI@EGF?@@FEFDA?F??BAACFFHHIE
@>chr21:9528751-9528814-0
GAAGGTCCTCTGCTGGTACCCAGGCAAACGGCGTCTGGAGTGGACCTCTAACAAACTCCAACAGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
G?IDFBABEBCAFEDHIEEBGDGGC??EG)DBGFCIEEIFD@DFFHC@ADCFBBHABEB@HACFEFD@FBCEA?IHGDDBBEC?BCHHF@@EF@DHBF@I
@>chr21:9528751-9528814-1
GAAGGTCCTCCGCTGGGACCCAGGCAAACAGCGTCTGGAGTGGACCTCTAACAAACTCCAACAGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
B@@GBACEIF9ABCBA-@@CB@F@IGADHGBFACIB?FB@DFCIDB?EGFCIGAEBCHGDE@?E@CCGDFG@@I???AAHBD?E@GHHAEFEF@IADBEI
@>chr21:9528751-9528814-2
GAAGGTCGNCTGCTGGTACNCAGGCAAACANCGTCTGGAGTGGACCTCTAACAAACNCCAACAGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
A@@GIBI(5GB?CH@AB?F,C@BIDGHFEC,HEI?CEHI?,HAE?FAIEEB@?DFC0GIDGIFCDCFAEGCEHIDAAB@IHCDHEA@HGA@GABI@CHCC
@>chr21:9528751-9528814-3
GAAGGTCCTCTGCAGATCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGNTGTTTGCCTGGGTACCAGCAGAGATCGGAAGAGCGAAAAAAAATCAAAA
+
DEH@HEBB?EGB@E?HHHHC@D?B.FABEAI?AFECGE@GHEAG?HGIGD&HFDDGD?CIEHCBGB?ADGFGACEIEEEFE5DHI@?@AIADDH(0@AEI
@>chr21:9528751-9528814-4
GAAGGTCCTCTGCAGATCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
F?@CCF?HHACG?AF0FHF?IHDEDDIIBH@DAGGHEEIABIHIHD?EDBAEAGBHBDHAGCEIBBCAGIE?EDB@GFB?CGDGH?D@F@IIEG@AGDFG
@>chr21:9528751-9528814-5
GAAGGTCCTCTGCAGATCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTATGCCTGGGTACCAGCAGCGANCGGAAGAGCGAAAGAAAAAAAAAA
+
E?B?DA@GFIDB?CHBF?EHB??EGAHDIBDCE@GEDBHBDAI@BEEDBHB@AD4@DE@AFCBGDIHFACGB*@I<HHEIFCF?@@E@E.BEDIBFEBHE
@>chr21:9528751-9528814-0
GCGGCGTACTGCTGGTACCCAGGCAAACAGCGTCTGGAGTCGACCTCTAACAAACTCCAACAGACCTGCAGAGATCGGCAGAGCGAAAAAAAAAAAAAAA
+
GHFGD???FAHEA@GFDEB?GBFCBDD?B?H?0AFDDFAD-CGDB?FH?C0??GEIFDHHAGCBGIGAA?FIHAHGHC'A?GGFCBCFCCDAEBBF@C?H
@>chr21:9528751-9528814-1
GCGGCGTACTGTTGGTACCCAGGCAAACAGCGTCTGGAGTGGACCTCTAACAAACTCCAACAGACCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAATAG
+
BEHHBGBDBAB=FHDBBHDDDAAIGECD?FIHC@CABCG@CBIGA?AEFA@HHADDD,HD?AHGI@DG@CG@GCFAEBIHCHFF?HGHIGE@?FII@'@,
@>chr21:9528751-9528814-2
GCGGCGTACTGCTGGTAGCCAGGCAAACAGCGTCTGGAGTAGACCTCTAACAAACTCCAACAGACCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
E@A?BEAEEGEHDABFE6HB?FAD@IIBDAB@HGE?DDIE.GB??HH@CAB?@BBD@BIFIGH@DEDDCB@AFIBDFEEDCBFEAI@?FBECGDF@ECI?
@>chr21:9528751-9528814-3
GCGGCGTACTGCAGGTCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCNGCAGAGATCGGAAGAGCGNAAAAAAAAAAAAAA
+
?@IIIE@?@AEF?D@CFHIC@EHC?A@IF??B?BIEB??AD@IF@BAICBHFGDABA@H?@AHBC@)I@GGC@?IHHDHAGD?B@2@IGBI@GDAFB@EG
@>chr21:9528751-9528814-4
GCGGCGTACTGCAGGTCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGAGATCGGAAGAGCGAANAAAAATAAAAAA
+
?@B@HFHFBC@IBCHDEBGBFGHHD@FEECHCIIIGBGHHHI;IIFH@@IG??EFCED@ICC@IBG??CE?EE?FFFH?DICIAGE@%IBBBD*IB?CFA
@>chr21:9528751-9528814-5
GCGGCGTACTGCAGGTCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGAGATCGGAAGAGCGAAAAAAAAAATAAAA
+
EGCCGGDAHCEIABCHHEAABCB?BG@@?FFICDIGEBB@?HDGBBHBGFDHGEGCGIAIDGDFECCD?EBEI?FGCH@DDEDBG?IBHA@FADI$GBCH
@>chr21:9528751-9528814-0
TCAGACGGTAATCTGCTGGTACCCAGGCAAACAGCGTCTGGGGTGGACCTCTAACAAACTCNAACAGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
@?D?E@IEI?FIAEFDAIBHHEHBDFHGBED??G?EHF?FB3B?GAIDAFGA@FHD@FHGA$HHEE@CDEC@F?CDICAAIA@HEC@A@GB?CAIDIFGD
@>chr21:9528751-9528814-1
TCAGACGGTNATCTGCTGGTACCCAGGCAAACAGCGACTAGAGTGGACNTCTAACAAACTCCAACACACCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
FF@I@BAHE4C?GAE@?GHFACDCF?@HCIAG?CAD7EE/@B@FB?BG%?AHFF?DGDFDEG@DAH=H/B@?BHE@DDB?HIFAF@IGFHCEG@?ECCB@
@>chr21:9528751-9528814-2
TCAGACGGTAATCTGCTGGTACCCAGGCAAACAGCGTCTGGAGTGGACCTCTAACAAACTCCAACAGACCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
DEBGGACAHAA@BGEFECIHDFADCEAB@@@?GCHFCEBIE?FG?DGD?HEHDGBCGAHHBH@EGEIEC?IDCCGBIBBFEBHBFGAEEA?BCCBG?D?I
@>chr21:9528751-9528814-3
TCAGACGGCAATCTGCAGGTCTNTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGTGTACCAGCAGAGAGCGGAAGAGCGAAAAAAAAAAA
+
BAAGB?EI-DIEGECAAHGBCB1AEHDEBDDCIACEEEDFCAFAG?DG??BEC@GEDAABAHHG.BGCGHFGDFDB@F)@GEFGF@DHA@BC@AAIEGDE
@>chr21:9528751-9528814-4
TCCGACGGAAATCTGCAGATCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACCCTGTTTGCCTGGGTACCAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
DF;EEHDB=??ACACFHDAIHCF?IGDAFH?F@AI?DBHBCHDFCEEDDAEG'ADEIIECAIFBEBGI?BC@?H?HECEAIGDAH@ECHIGEEEHBB@FE
@>chr21:9528751-9528814-5
TCAGACGGTAATCTGCAGATCTGTTGGAGTTTGTTAGAGGTCCACTCCAGACGCTGTTTGCCTGGGTACCAGCAGAGATCGGAAGCGCGAAAAAAAAAAA
+
ECGBEDBEEA?CEGGDEFGAHCCBIHGEH?E@?FAIAGDGGAAGBEBAIBA@IHI?DIFHFACIC@?AA?FCECHICDBHB@BDG<@EHI?AFIB@CGIH
@>chr21:9528811-9528998-0
ACCACTATGTCAGCTGACGGTCCTGTCTGTTAGAAGGCAAACTAACAAACAGGAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAAAG
+
HDCDDDFCEGADHFC?F!DHGGI?H@FEDFF@?GGBF?@DAFEBCCDHDDE@2?@HF?G?BBBADIGCIBB?GE?FDE@CD?DHBGEDIAHDB@?FE@@D
@>chr21:9528811-9528998-1
ACCACTATGTCAGCTGAGGGTCCTGTCTGTTAGAAGGCAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAAAG
+
ECA?F@EGEFCCEG?GAG?BCECAEIHCEGIGFI@EB@G?AACHCCFAEF@?GIBEH@CCFIHIGAEHBGBH?CDFHFIE@FH@FAHCA@F@BD@E?H?E
@>chr21:9528811-9528998-2
ACCACTATGTCAGCTGAGGGTCCTGTCTGTTAGANGGCAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAAAG
+
I?BF?BGEHIB?IFCG?B?HICED@DF@@IA@BI3CEHI?CCH@B?AAHFBE?AEADIEBBGCGG@HIHI@GB@D@CEEIDIG?BF?EFHGCE-IFDHCF
@>chr21:9528811-9528998-3
ACCACTATGTCTGCGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTTCCNCATCTTTGTGGTTTTATCTAC
+
GA?GGFDIB@EEGC@DEFABC@@C?HACD?GE@@HBAF?D?IA?IGI@@CEC@@F@@ECACHH?II?D@AF?DCCBBA*EEEIFIAEH?IAAIGCIEFEC
@>chr21:9528811-9528998-4
ACCACTATGTCTGCGTTCCTTTGGAGGAGGAGAGGCGCACTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTNTCCCCATCTTTGTGGTTTTATCTAC
+
C@BBIF@@FFI??HCDGDDDIIFIGI@?AAGF?CGGHI3GDGAAA?BFCH?EDGB?@?CEEIGI?ADCECE@@D:BABGBEEFHCB@IGB@AHGFFG@EC
@>chr21:9528811-9528998-5
AGCACTATGTCTGCGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCTAC
+
A3HBACHADGHCFBBC?FA@IAII?FGHHDEDEI?GGEEAAA?ICCFI9FGFGC?GDB?GEDHFGAHGEA?CC?D@IC?GFCHDF?HB?@FFGHIABDDF
@>chr21:9528811-9528998-0
CTCATACCACGCANCTGAGGGTCCTGTCTGTTAGAAGGAAAACTAACAGACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAAA
+
GCACAE?ADEIFH.B?@GCICC@I@!AGEBEHFFEGGHFEEGBIFFIA#CDGF?FHA@EBDHBFIIIDH?DGFICECE?EABFE@GHGHABBHC@GCGDB
@>chr21:9528811-9528998-1
CTCATACCACGCAGCTGAGGGTCCTGTCTGTTAGAAGGAAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTATACATCACCATCATCAAA
+
FBIF?EBADCI?FBFIEAG@D@HGBGDC?BBHAAHHG?D@?@FGGFBCDBA@CFAE@BDDIH??AEEF@?EFED@C?AFDE#?B?E@GCFFFDHFBFA?C
@>chr21:9528811-9528998-2
CTCATACCACGCAGCTGAGGGTCCTGTCTGTTAGAAGGAAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCNTCTGTACATCACCATCATCAAA
+
EBHGIDHHFD@???CEEGCHBCBC?DEHDE@EFADCAEADE@CH@HA?G?IGAFAFC@@GCFBHGE?HDDBFBIBIE4@D@@C@BHBIFDHF:BEF?B@G
@>chr21:9528811-9528998-3
CTCATAGCACGCTGGGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTACCCCATCTTTGTGGTTTTATCTA
+
DAGCAA!AA??IFE3DFFC?FAGBC?DHDD@CIABGIGCAGIGG?FG?ICB@AG?AHDIFAFIFB?HAA@HAB@?I/IHADHDDHEEACCFEE@AHFC?C
@>chr21:9528811-9528998-4
CTTATACCACGCTGCGTTCCTTTGGAGCAGGAGAGGCGCTCTGCTTTTTAGAGTTGCCAGTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCTA
+
HI*H@FAGF@IFGHA?C??C%IIDCEH9?CGHFB@FD?@FCG@D@?A@?EG?FEB#GDAGDE??BF?HGABCDFDIDBBGEBCFHFIAI@ACCFGGIAFI
@>chr21:9528811-9528998-5
CTCATACCACGCTGCGTTCCTTTGGAGGAGGAGAGGCGCTCGGCTTTTTAGAGTTTCCAATTTTTCTGCTGTTCTTTCCCCATCTTTGTGGTTTNATCTA
+
CBFHACIEEFCFGHHBD?EACEIA@??CGGDIA@FGECBA@=HEAHHBGGFFCHF?AB?&HEF?GGGDAAIDD$AECAHBBA?EFCBCB@HG?E;III@A
@>chr21:9528811-9528998-0
GAAGGTCCTCAGCTGAGGGTCCTGTCTGTTAGAAGGCAAACTAACAAACAGAAAGGACATCAACACTAAAAACCCATCTGTACATCACCATCATCAAAGA
+
BGCA?HHHIIG??DFGC?DHHECACD??DDBDDCHCGD@BGFCDACIEI?AF?AI@B?II@:IE@HGHAHDIEFE?@EAFAFC3FCD??FD@FDFDFEFC
@>chr21:9528811-9528998-1
GAAGGTCCTCAGCCGAGGGTCCTGTCTGTTAGAAGGCAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCGTCATCAAAGA
+
BBCH@BAIGFHDB,BAEI?G@D@?FBHIG?FDHFFE@GDFC@EHEF?A?AHACAABEDAAEBFDHB>BEF?AEGBD?AFDGEG?GIG?F&CHGI@EH@FF
@>chr21:9528811-9528998-2
GAAGGTCCTCAGCTGAGGGTCCTGTCTGTTAGAAGNCAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAAAGA
+
FIFCC?H?DACD@@C?EIDFHGBB?CIGDACAH@@:DCH@FECABFGAI@?GBABEC@GDHACEH?@?CEFD@H@@FIEBDGDEEGC@@ICCGC?C?E@F
@>chr21:9528811-9528998-3
GAAGGTCCTCTGCGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTANTTTCCCCATCTTTGTGGTTTTATCTACT
+
IC?GFFDFHBA@EGADBDDA@@?FEDGEABA@@FHI?ICDHE?BCE@GB?EII@C?BI@BBFEHC@H@AA%8@GCB?AH??GDFIACECGFAIIAHFC@?
@>chr21:9528811-9528998-4
GAAGGTCTTCTGCGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCTACT
+
CIG??EH.IGEB@CAIBEHA@?AE@GB@?A@IAADCCACDI?BFCIIC?ICHAAII?@C?EC@IGH?CFE??BIDIGGCAIGEII?B??IFIEDIA?IDC
@>chr21:9528811-9528998-5
GAAGGTCCTCTGCGTTCCTTTGGAGGACGAGAGGCGCTCTGCTTTTTAGAGTTTCNANTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCTACT
+
HAHDCGDBHC@BDHBCF?DE?BG@C??+HHDEDEEEEFDBEGFC@FGIA?AFFC@3D5IDF@@AGBDIE?@BB?BDI?B?@D@I@D@DBG??CC?DCI?F
@>chr21:9528811-9528998-0
GCGGCGTACAGCTGAGGGTCCTGTCTGTTAGAAGGCAAACTAACAAACAGAAAGGACATCCACACTAAAAACNCATCTGTACATCACCATCGTCAAAGAC
+
?CC@D?G??E?CFC?DGDBB@@EFIEF?BIAIH?B?BCDCHG@?@BEFI?IFBDAC@C@IF@CBIAAIIG@F6BA?I@ACGB@@GFEGCFD'GBAGDBGC
@>chr21:9528811-9528998-1
GCGGCGTGCAGCTGAGGGTCCTGTCTGTTAGAAGGAAAACTAACAAACAGAAAGGACATCCACACTAAATACCCATCTGTACATCACCATCATCAAAGAC
+
@C@HGDD%H@?I@G@?CFFBFGF@??BHIEEDFIDCGBAHBHACDCH@I@@DFGCGDCDAIDHHE@EE?'FHDEEDHI@IHHFCFGGFFF?FBDHFECAA
@>chr21:9528811-9528998-2
GCGGCGTACAGCTGAGGGTCCTGTCTGTTAGAAGGAAAACTAACAAACAGNAAGGACATCCACACTAAACACCCATCCGTACATCATCATCATCAAAGAC
+
?DICAEACG?D?HIFFIIGBGCGDDDCDHFH@IBAFAD@@HHC?HHDHF?.DCCEDD?CE@AIC?GIA@>F?BGCHH5BD?ICI?G<AF@GFCC?@DFDI
@>chr21:9528811-9528998-3
GAGGCGTACTGCGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCTACTT
+
C)?DI?DHG?IHD@CEFBIFFA@A@?HBAC?CCIEICHDFHHDBBH?AFAAE@BA@IACIAF?FCFGCCEGEHAGADEC?FF?@EBDD@HHAI?I@DFAC
@>chr21:9528811-9528998-4
GCTGCGTACTGCGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCTACTT
+
ID'?BH?GGHD?AAGBFBFIFFACEDDFHHEG?E@AGIIDDHIGCE@FCIIBBC?IGAIFG?HI?A@DH??@@HIC??HBHHCCBFCDFGIABCAB?G@D
@>chr21:9528811-9528998-5
GCGGCGTACTGCGTTCCTTTGGANGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCTACTT
+
G??IDDIFFE?@?ED?DBCHAFD<AEFH@?IH?BHFCCIAAFB@I@F@?HAFEB@@ABB?D?GICHDCIICCEF?IGC?BIHBGIC@BH?)CDC?HACFA
@>chr21:9528811-9528998-0
TCAGACGGTAATCAGCTGAGGGTCCTGTCTGTTAGAAGGCAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAA
+
FIH?DFFFHH?E@FDHGIDGED?ICGFBCGABEGABB?DDBBACAIEC@ACBEF@E?ECEDCH@G?CF?@AIICFGBFAB@?G@EAI@HA@A?A?IF?IA
@>chr21:9528811-9528998-1
TCAGACGGTAATCAGCTGAGGGTCCTGTCTGTTAGAAGGCAAACTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAA
+
CGEHDACDA??GAA??FBGIHFF?IEBGFCD?EBDBDB?IHHG??@FDADBAHAECFBI@I@@GBIDHDCIE@AA??IBABAAHDCGABA?BHI@AGFD@
@>chr21:9528811-9528998-2
TCAGACGGTAATCAGCTGAGGGTCCTGNCTGTTAGAAGGCAAANTAACAAACAGAAAGGACATCCACACTAAAAACCCATCTGTACATCACCATCATCAA
+
@BI;FGECBGFCGAE?FHDFBB?EHCD!;GIIHFGIEE?DBE?6EBC@HGCIEIEICCHGB@GDC@ECC@GD?BFAAFBHBEB?HG@FBDAHFAEGHCCC
@>chr21:9528811-9528998-3
TCAGACGGTAATCTGCGTTCCTTGGGAGGAGGAGAGGCGCTCTGCTTNTTAGAGTTTCCAGTTTTTCTGCTGTTTTTTCCCCATCTTTGTGGTTTTATCT
+
F@IFD@DA(AHEG@@F?HEIBGF5EHEAACG@?GADGCGECBCBACH>I?GHGDEGHCHGHDGECBEHBEFEDCB@D1@IAGG?CCF?IGDIBFAICFHI
@>chr21:9528811-9528998-4
TCAGATGGTAATCTGCGTTCCTTTGGAGGAGGAAAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTGCTGTTTTTACCCCATCTTTGTGGTTTTATCT
+
C@A?B;DEHCHEFCDGH@HIBCHBE@?CE@BGD!@ACF@CHCAI@FBEABFAEDABB?ADHB?GEBEEEAB@GHIHA4IIGGIIICBHFFDE@CE?A?FB
@>chr21:9528811-9528998-5
TCAGACGGTAATCAGCGTTCCTTTGGAGGAGGAGAGGCGCTCTGCTTTTTAGAGTTTCCAGTTTTTCTCCTGTTTTTTCCCCATCTTTGTGGTTTTATCT
+
BDEAAHH@?F??7'CFB@FIAFG?IFFIDEGH@BDFEA?EAGAHE@BEGF@GBGAHCC@HA?EGAG?C'@HFDIBCFIF@DEIFG??HGGAC@@DDFA?I
@>chr21:9536511-9536665-0
ACCACTATGTCTGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATACA
+
GA@IIABG?DHIE?FBG@@DC@FD?CACAIIHFH@FA?CGCDE@@@BDFII?IGIIH?DA@IC@DGAIGI?EDECBCABIBDDAABEFFEE?I@EF@AII
@>chr21:9536511-9536665-1
ACCACTATGCCTGCAGGGTAGCATCAGTCCATCTACTGTAGTCCGATTCAGATTCAGATGGCCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATACA
+
CE?@C?F?A)D?GB?DGD@??DEBFHHAAIBDH$DFI8E@EFHEHCFHIBI?@@C?GGFAB*I?GEDADIH@HE?IGBCAEIGDGHAFICACG?DBBCCD
@>chr21:9536511-9536665-2
ACCACTATGTCTGCAGGGTAGCATNAGTCCATCCACTAAAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGAGGAATTCCTAGTATAATACA
+
EDC@FBCIAGB?CDGEBEG@CBCA,HBFEBDAEEDEHD5G@@?AIIDEI?CBHEI?F@?HH???BHBCBCBD?HI?@BA)GGCHADG?C@@HAHIIAFAI
@>chr21:9536511-9536665-3
ACCACTATGTCTGCTTGAACAGTGCCAACGTAAAGGATAAAAATCCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTA
+
DGHIE@AG@@CBEHB?CHFF@IFDI@HGBADEHH@@EHE?HEF,HG@A@BH@@?FDBHDF@H@@EDGBDGH6FIGDBAADA@@GCHAFEBCIAG?F@ED@
@>chr21:9536511-9536665-4
ACCACTATGTCTGCTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTA
+
@FAEHBC?ADGADFBACHH@FGGFDBFIEB@AHGEAIC@H@AG@AECH?ECHDIHAGIED?EGC?ICDH@EBE?ACDDGCHDAHEIHBEG?GI?I?EFFG
@>chr21:9536511-9536665-5
ACCACTATGTCTGCTTGGACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATNTTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTA
+
#EEEEBBHHHED?BGII+BIGFHCDFFFHFCAH@BFHBDGGGGBFHHEB?F@BA?#G@AGDI?HIAEG?GI@GGEB?BBGGC?ABCHIA@HFDII@HH?F
@>chr21:9536511-9536665-0
CTCATACCACGCTGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGGATAATAC
+
CHAFDEDBACHHHGFDHDIDCIIGB@@IBFFGEFCBA@?CFAAEDB@GDIHA@E?EBCF?BFC?CC?IFBH?BI@@GFFIDBDCFI?BCACD7@EBEHI?
@>chr21:9536511-9536665-1
CTCATACCACGCTGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATNCAGATGGTCAGATTGGACTCTAAAGTCGAATTCCTAGTATAATAC
+
DG@DAIFG@ICIEGAA@HDBH@GHGFBACEIGAH?GBABAAHDC%??CGCEE@E%ABEECDBFIHCBFHD?C?I@H@DB?G$FADCDI@?DBH@GHBDGD
@>chr21:9536511-9536665-2
CTCATACCACGCTGCAGGGTAGCATCAGTCCATCCACTNTAGTCCGATTCAGATTCAGNTGGTCAGATTGGACTCTANAGTGGAATTCCTAGTATANTAC
+
FGGHICIH@ICEGG@DDHBA?CIGBIGEEBFHHA?DHE>@EBE@HF@HGDGFDC??EG*CIE?CHFA@??@BB?EEA0BCGDIG?IBA@E?FB@ID6?EF
@>chr21:9536511-9536665-3
CTCATACCACGCTGCTTGAACAGTACCAACGTAAAGGATAAAAAACCAGAAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTT
+
HC@CIFHDA?G?AEAFDDAGHH@EDCDBDDIEC@IBGGE?BGEGFC@B@/FDGBAAHBFBFB1FCI?AAEEBECBFFHCHGHBAGAH@?A?AIDFEICGC
@>chr21:9536511-9536665-4
CTAATACCACGCTGCTTGAACAGTACCAACGTAAAGGATAAAAAAGCAGGAACCATATTGTNAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTT
+
EA1EF@I@AIGIACAG?E?F@BCH@DDFG@@CG?BH?FHAFI?CF6CFCB@A?EBAFDFFG!D?C?BD?ADBC?HDF@BGDCCGDDEGFF@FHAAHHA@C
@>chr21:9536511-9536665-5
CTCATACCACGCTGCTTGAACAGTACCAACATAAAGGATAGAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTT
+
FB@DFFGA@B?C@GI??@?CH@BH?E?BDC*C?BIFE?AG6IACEBEEHDAFAFI?GGFC?GGADECDDIBCG@E@EICEGAIHCA?@BIA@DA?CDFBH
@>chr21:9536511-9536665-0
GAAGGTCCTCTGCAGGGTAGCATCAGTCCATCCACTATAGCCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATACAG
+
GF??E?G?D?BC?HDH@F@IADI?HBCAHF@BCEAHBAAE)IAGDA@BICAAIBEHD?CCBI?HBDGCHDDCHEGBG?HGHBGFCDA?HBAG@HABIEHD
@>chr21:9536511-9536665-1
GAAGGTCCTCTGCAGGGTAGCATCAGTCCATCCACTANAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATACAG
+
H@D@CEBDDBFFAIIE?HFCHI?@DEEHHEHDFBGDG:E??CGFIGDC?FI?H@ECB?IAHFIGCIEGDFICFC?HEAI?FIBGB?AIAFEB?CDC?HCF
@>chr21:9536511-9536665-2
GAAGGTCCTCTGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATACAG
+
BCD?ED?CCF@AGGIHGH?IG@GFF@FDFBGCIEIBBACG?@?FFBECHEECGHACBCA?AGIADIAD@EFF?I?IG@D@CFEF??E@AE@HHGCGEHBE
@>chr21:9536511-9536665-3
GAAGGTCCTCTGCTTGAACAGTGCCAACGCAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTAG
+
C@AIG?CCB@@@G?CA@BBIFEFF@DIAD$C?CAA@?FGHGBEEFABDGEAEFHABIF@CF?DBB@GAGGIAFIH@ADF@CFGFBBFHB?GG?F?F@HCG
@>chr21:9536511-9536665-4
GAAGGTCCTCTGCTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTANTATACTAGGAATTCCACTTTAG
+
HCG?I?CHFBBA@H?@FDCHFICA?EGEHFDA@AE?DFAE?BAG?HEBIBCIGHB??C@GDE@AIBHIEACDGHAAA1DAFCAGHCBGA?@CHG?ICD?A
@>chr21:9536511-9536665-5
GAAGGTCCTCTGCTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTAG
+
GBBDIECAGAD?FFGHC?GI?IIEDCHIA?H?GHD??G@GCBB@IB??F?BFEDEBEGD?FF?DAH?AGC?GF?F@?IFE@IGBFBAAIH@C?DIDDADD
@>chr21:9536511-9536665-0
GCGGCGTACTGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATACAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATACAGT
+
DDE?GBH?BIH@GI@=CD?%DIHA?BBCB@@EAAB@@?AACGFHAFC@CDG.GEIIIBIGIGBDFAIA@B?@EH?AHIF@FABG?IHHDCIE?EG@IGFH
@>chr21:9536511-9536665-1
GCGGCGTACTGCAGGGTAGCNTCAGTCCATCCACTATAGTCCGGTTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATACAGT
+
DAEIEG@BCD?GFGHCGI@@*GIEFDFIDBD@GHHAFEBED??;IA?H@BIDEGHIG?BGIIECHCBBE?ACC@H??BECFHGHEHAGIEDDCGA?ADGD
@>chr21:9536511-9536665-2
GCGGCGTACTGCAGGGTAGCATCAGTCCATCCACTATAGTCCAATTCAGATTCAGATGGTCAAATTGGACTCTAAAGTGGAATTCCTAGTATAATACAGT
+
?AEFDEHG@IC@HEGHI@EBC?HFCCII@CACD@CD@D?@FH+AF?CIGDA@AA?IBBI@AH<GFE@@?H?EDB@@FCCDBE@ABHEE??@CH@GBII?@
@>chr21:9536511-9536665-3
GCGGCGTACTGCTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTAGA
+
A??B?G?ADGIGDC?A@CH@F?IGEBGACCGHCCGF)I??IHCBHFB@B@BC@GECFCDC@?GEDBC@E?AFEFAEAGAD????BAIGHE??E?D?GBFC
@>chr21:9536511-9536665-4
GCGGCGTACTACTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACAATATTGTGAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTAGA
+
CHD@EIEAEI9?H@AHFGDHCCFIF?GFA?C@@BBDGI?BD@BA??G?@D/@?ECB?B%CCCIIGE?@BHA@FB@BGG?CBH?C?AEIDF?HDHHGAFF?
@>chr21:9536511-9536665-5
GCGGCGTACTGCTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTAGGAATTCCACTTTAGA
+
?C@GADIIIAIHGIEFAG?CG?IIBH@F@CHCBHIAHHDCDGIA@HABC@I??@IG??HAG@FGI@A?HIE@BH?@FBEBEDEH?DCGGIHI?EAEEGGC
@>chr21:9536511-9536665-0
TCAGACGGTAATCTGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATA
+
?BIFC@HEDI@@GDCIHGH?EIAGFI@E?I?BCCBECIC@DGDHGH??EGBFI@CHDFEAGI?EHACCCIGCG@IIHBHI?@@GI@@GHGCB?A@EB@CC
@>chr21:9536511-9536665-1
TCAGACGGTAATCTGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATA
+
IDAIGI?A?AI?C@EDFHGE@C@AHBAG?IIHC?HDEACHEIIHBBCE?DC@AEEFA@@EG@BEFIBFDIFBBD@@CAHDFDHCGBH@BCGHEFIB?AAA
@>chr21:9536511-9536665-2
TCAGACGGTAATCCGCAGGGTAGCATCAGTCCATCCACTATAGTCCGATTCAGATTCAGATGGTCAGATTGGACTCTAAAGTGGAATTCCTAGTATAATA
+
?CD@ABA@ICGIB#FEEB?CEDCFC?HHBAE?IBBFI@GBA?EGGF@@FGACCAGFDIGAID?HA?FGIHF@?EFI@CIAEAFBFIH?AG@DDFGIFF@A
@>chr21:9536511-9536665-3
TCAGACGGTAATCTGCTTGAACAGAGCCAACGTAAAGGATCAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTATACTATGAATTCCACTT
+
HBBIFFI@IDB@G@?CFAA@CGD@,A?ADAAEBCHFFDG@*GDE@?DI@@CHCAAE@GFCE??C?@@II@?BEI@HGBC@IADDBB@C6G??HCAH?FD@
@>chr21:9536511-9536665-4
TCAGACGGTAATCTGCTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATTACACTAGGAATTCCACTT
+
AACFFBHC@AHAFC?A?AFICHG?IEIHAHDHACC@I??DHCCECD?IHACEFEE?GDFBIBHEHBDIGCBGII@FAGDBHHH3?B@@EEGFA@BECCB@
@>chr21:9536511-9536665-5
TCAGACGGTCATCTGCTTGAACAGTGCCAACGTAAAGGATAAAAAACCAGGAACCATATTGTAAGGAAGTGAAGACTGTATNATACTAGGAATTCCACTG
+
FHBDAFIBB+IB@GB?HCGFG?AIED@GF?D@EA@GDDGAFE@GDIF@HH@@AEHAHFBAGADBHH?B?H?CFIGB?IEDE1BHDGE@HH@AFGABGEA;
@>chr21:9540767-9540907-0
ACCACTATGTCTGCGTTCTCCTAGGCACAGACCCGGGGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTG
+
FGEHG?BCD?AHBEAEFBIDBGH@HG??HEE?FFGA9GAFC?ADAI@CDDD@FHBDDH@DHFCH@IAADDFBDDIFH@AHBIBDDDDHBICEDCACBG@E
@>chr21:9540767-9540907-1
ACCACTATGTCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTG
+
A?CCCIDDHGBF?B@DHFDBBCCGGFD??@CB@AEC?H@BC@@A?AGDG?CCAH?I?EEHAG@@A?BHICE?II?7BD@ED@@?DCFHCDF@IF?HEDIE
@>chr21:9540767-9540907-2
ACCACTATGTCTGCGTTCTCCTAGGCACAGACCCGGAGNGCGTTGCGAGGCCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTG
+
?IECIF@EDCDGCAFIEIEGFHE?CDB?F?HBHDAEGD8DB;IHG@@BFD;F@A?F?CFDGC@GBGIAHIDFH?DBHE#CDAGDHAC?AD?GAHHAGFH@
@>chr21:9540767-9540907-3
ACCACCATGTCTGCAAACAGGAAGGAGTTTANTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGAAC
+
I?EFE6DICDFDHIHHBHDGDIAFFA(BAC@0CHCFGFFFGE@@IDGE?CC@BGI?GGH?FI@?E@GCG@BDC?H?ABGCBGDB@BGHAFEIB@FGAH?A
@>chr21:9540767-9540907-4
ACCACTATGTCTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGNTCTGTGCAGAGCAGAAC
+
FCI@F@GAAFFHCGAIAGDAEEGFA@DGE@ACADADCAF?IBEHEGAC?EBC@IBD??DIGFA@EIHFE?HGHHE@?@GFIE5IIBAGB@DFI@FB?@HI
@>chr21:9540767-9540907-5
ACCACTATGTCTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGAAC
+
ECGDAAIIBGBGIIGFCHH?EGG?BA@GCIFFHGI@HDDBGACBGDACEBDHC@DIDGBEIIGH@BI?AG@IAHC?CDDAGGGAADH@FAFBI@E@?HH?
@>chr21:9540767-9540907-0
CTCATACCACGCTGCGTTCTCCTAGGCACAGACNCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTACTCTGCACAGACCTTGGGGCACTGCCTCGCTTT
+
CAICBH@CEG?BEGFICDECAFBAC?E@F@FC@=B?GFHBCAG?CIBCA?IHAFIDAF?GI?GFDA=BIEE?@CGCDICI@CG?IFHGGGHHFFAHEDAC
@>chr21:9540767-9540907-1
CTCATACCACGCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTT
+
?@FIGHC?@CGEHBHFD@FF@B@?CEB?FD?GBFAGEFHDDG?CH?IGB@?G@HIAFA@CBH@FAD?GBI?@EHCCHBFH?AHDDCHGGHFFBH?AFFE?
@>chr21:9540767-9540907-2
CTCATACCACGCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAACCGCGTTCTGCTCTGNACAGACCTTGGGGCACTGCCTCGCTTT
+
CBBG@BCCA@AHBGFFH?BADCHEHBAACGABHEHDEAE@CACHFGEIIDEHIIFA)CHBEGEFIGEHI@DH(EH?DIAFDEDHBAHIFIFBFIFCI@DG
@>chr21:9540767-9540907-3
CTCATACCACGCTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGCTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGAA
+
BAHHIH@IFDDFGEBBFH@?FEHBFII@@BGCHDD?BAF?IGABEHEG??GIG@?&AHHH@@FEIHCEH?GBI@ABFHFCIDIFHGCA?EDFG?HDADIB
@>chr21:9540767-9540907-4
CTCATACCTCGCTGCAAACAGGAAGGATATTATTCACCGTCGATGCGGCCCCGGGTTNTCCCAAAGCGAGGCAGTGCCCCAAGGTTTGTGCAGAGCAGAA
+
??BGDBGA;B@?@GDED@DG@CBF?@?D<ACDADABCGHDHE?I@ICBDDBEADI?@*EG@HC@GC@CFAADHGEDBACE?CBCI%E?@EH@GFBCDCHG
@>chr21:9540767-9540907-5
CTCATACCACGCTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGAA
+
H?EEFD?BAGICD@?HA@ADIIHHFIFEAHADEDH@A@IAE@@A?AECHB@CFFC@@DBFFFGH@@?GIDGIACDICCFDD@DCDIDG?CH?CA?@CFID
@>chr21:9540767-9540907-0
GAAGGTCCTCTGCGTTCTCCTAGGCATAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGGTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTGG
+
GHBCDHADCEEDFBDBI?F?GD?CID8@D?HBABC?GADBDCICIBI?CG?GEDF?HCE?1?*EGEHI@GBFCGAGH@B??@?GG@FDH?FGFI@EEGAH
@>chr21:9540767-9540907-1
GAAGGTCCTCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTCG
+
@@FECHAI@GBBABCE@AFIGCBAABA?EFEBCGAACAIHGFABIEGEEGGF@EC@B#?A@DIEBI?EG?DBC?CDECFHCCHGHHBEDHDHFGHB?H=?
@>chr21:9540767-9540907-2
GAAGGTCCTCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTACGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTGG
+
GE?D?GCFE@CCF@F@G@DAFF?E?@BB??FBEABFDGCHHCH/BGHBCBCFCDCA@B?EFII?CF@H?GEEGADG@D@I?FF?BIDBDCCDGC?HFDC@
@>chr21:9540767-9540907-3
GAAGGTCCTCTGCAAACAGGAAGGATGTTATTCACCGTCGATGCGGCCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGAACG
+
F@G?BCH?HDBEIFG?ECAIHIEEDA&GFAGH@FCCDFID?AHE?EBEBDE?IADFBC@HCBBG@EIAIIDGA?FGABEFE?BECBEDGIFBBGDIAFHD
@>chr21:9540767-9540907-4
GAAGGTCCTCTGCNAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGGCTGTGCAGAGCATAACG
+
EBGGGBFH@BAA?-CGGCAEECDGAEFG@FID@IIE?@BCHCFGEFE@IICHB?FD?@AECD?AFIDAIBGC@?GGGBE?CF=@@HDFHHDFCDA3EDG?
@>chr21:9540767-9540907-5
GAAGGTCCTCTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGAGTTGNCCCAGAGCGAGGCAGTGCCCCAAGGTCTGAGCAAAGCAGAACG
+
FFAHHACGAIGDFIHCHAGB?H?HACGBDH?GFCIAAHCIDIDIGA@BAI@IF@C@/?@GF2@HDCGDEBHGEBCDE?AAHFC?@D>EID;F?CHHGC@C
@>chr21:9540767-9540907-0
GCGGCGTACTGCGTTCTGCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGTCACTGCCTCGCTTTGGG
+
A?IFCC?BDIECECEHI+?ADIF?G@IGFAAIIA@CAC@ACFDABHAIIADAIAHIHAD??BGCEEDCGFH@DGHECD?E@?.HECBHGH?@FHHGDCFI
@>chr21:9540767-9540907-1
GCGGCGTACTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCNGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTGGG
+
FBHAFC@DIBA@AD?GBEHAFACI@CIHBAI@AC?DIGIABHDEGGG?CD@AIH@+EDIDI@EIBAEB?IFGE??HADEAIAI@F?DEHIEFF@FHDFGG
@>chr21:9540767-9540907-2
GCNGCGTACTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTTTGGG
+
II1@?@EADAH@@EFHA@@?D@AIIHC@IHADHHCFHEEB?IA?DCHCIE@CFHDEE?DB@D?F@AFBEGI?G@A@CGAAF?AA?GEDAD@EACBGG@?A
@>chr21:9540767-9540907-3
GCGGCGTACTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCNAAGCGAGGCAGTGCCCCAAGGTCTGTACAGAGCAGAACGC
+
CFH?CFCB@H@?=ID@=@@EAFD?HI@7EHA@ECDC@IEGD?@HHDIEI@ACBFGAB=E#?ABGCHIBI??HBFACHFFEHEBICB:A@ICFCG?CDAGC
@>chr21:9540767-9540907-4
GCGGCGTACTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGAACGC
+
BEBIAGBAHFIFIFCD?@,?DEABH@DCGAB@EBHCEGD?F?AGBEC@FIBCCEABCEHHH?EB@EDD@@FDFCGA?H@B@?FABCCGBHDIDDIBG?AC
@>chr21:9540767-9540907-5
GCGGCGTACTGCAAACAGGAAGGATTTTATTCACCGTCGATGNGGCCCCGGTTTNTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGAACGC
+
@IAAHI@DBACHHGECBHF@?ICHA/BCGIAIBB@AHHC?AI!EBFEADEC7HI9@?F?BAAEDAGDB?EG?EADEG@FACCIB@BCECGIICHE?FFEE
@>chr21:9540767-9540907-0
TCAGACGGTAATCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTATGCACAGACCTTGGGGCACTGCCTCGCTT
+
IDCGFEHEBAEEAFDECFG?H@HEEGDE?HBBAG@ABCDBBDIG?E?ECE?DBAHE@AAHGE@E@D?AEI,I?CDCB@A??@CAADBD@@@EFBBAGH?I
@>chr21:9540767-9540907-1
TCAGACGGTAATCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTGCGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCTCGCTT
+
FCICBDCFGD@?GG@EIHA@CDFGH?IEAGGB?CC?CFBIG?@BHB@GHI@E@IB@@AEIEIB@IAHC?FAGG?EDCB@@IIIDAGBAIC?GCCGAF?@D
@>chr21:9540767-9540907-2
TCAGACGGTAATCTGCGTTCTCCTAGGCACAGACCCGGAGAGCATTACGAGGGCGGAGCCGCGTTCTGCTCTGCACAGACCTTGGGGCACTGCCACGCTT
+
DHBAFG@HC?@A@B?IDDEFD@CAD@IHD?ICB?CD?A@DE??EEH"GEDDAF@@DCIC@DAEF?AGACDGIDCBADIFHI?@GHBHD?B?AGB#@I??I
@>chr21:9540767-9540907-3
TCAGACGGTAATCTGCAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGA
+
HHA@H@DBCIABIEAIG?B?ABDFCADG?@?H@?B@@?ABFHEFEE?AFIIGC@GEEAHA?AA?GFBDFACEIFIFICG?EEIF?HE?IFC@DEI?@@CD
@>chr21:9540767-9540907-4
TCAGACGGTAATCTGCAAACAGGATGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGCGCAGAGCAGA
+
GABCG?@DDCF?CICHDHGDBA?C*FEA?EF@EAGH?GACEDED?GIIFBDAG@EBEI@?BHCEHBGGCGADADGIAEADDACE@FB@I)CDDFHCB@HB
@>chr21:9540767-9540907-5
TCAGACGGTAATCTGGAAACAGGAAGGATTTTATTCACCGTCGATGCGGCCCCGGGTTGTCCCAAAGCGAGGCAGTGCCCCAAGGTCTGTGCAGAGCAGA
+
BBFDFB@GFHCFI@G4DGEHIDH@ECG?GCH@IIBBCBG?DIH@DIAH?IGCH@CCB?BH?GGIBFCIGBFE@I@HCHA?GBGFHF?A@?GHAIEDIE?I
@>chr21:9540989-9541087-0
ACCACTAGGTCTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCANGTNTCACTGCCCGTCTTGGGTGGCTGGTTGGGTTTGCTATCCGAGG
+
A@AD@?E8HFEE@DBB@H@EFEEF@DFH@BHCECE?@H?@HFC?ECG@EBIEB=I?-@BCEHHIGHB?ECCAA@BFDBI?BEH?ICA)HFIADIF#GEI?
@>chr21:9540989-9541087-1
ACCACTATGTCTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTGTCACTGCCCATCTTGGGTGGCTGGTTGGGTGTGCTATCTGAGG
+
C?B@I?EIHDGEIIDHAFDD?HCABBEFII@AA@@IACHGFGCA?B?E@@EAEHIHGG@?E?IF?@C@AEAIHIE@EIGB@CAFGGHAE?BBHFFBF?F@
@>chr21:9540989-9541087-2
ACCACTATGTCTGCACTGCGGGTGGCCTGTGACGGGTTGGGAGCCCTATCTCAGGTGTCACTGCCCATCTTGGGTGGCTGGTTAGGTGTGCTATCTGAGG
+
HEBAHEHI@??FG?@FAB?DCG??IBGID+?ICB?F??HGICDA@EAIAIDHGEF?DFIAEEH@@DC??AGBHIF)EF;G?EF3FDGBDCBEB?DCFE@I
@>chr21:9540989-9541087-3
ACCACTATGTCAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGATGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACCCG
+
DF?FDAHIDFEIAG@HBHFEGGIAGFGFCFCB?FCAGH?EBDCC?B@@HAFDHGBFDBGIFGCEBCHEE?DBBHDCGDCFAHGBE?CAIHGEB?CG@@@F
@>chr21:9540989-9541087-4
ACCACTATGTCAGAACAGGCTCAGATAGCACACCCAACCAGCCACCCAAGATGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGTCACCCG
+
?I@IACFCBC?@E:AAIC2IGIH@ICEDBBGEBBI?CHFEBGFFA??DE@I%EEHDHB@FIC?BAFIIGF?BIEEEE?EGFG@AH@EFHBGGE,IAFI?E
@>chr21:9540989-9541087-5
ACCACTATGTCAGCACAGCCTCAGATAGCACAGCCAACCAGCCACCCAAGACGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCGGGCCACCCG
+
IEEHGDEDEDIE@DAHEHBB@EH#?BF@GAIA=F@E?@BAHDDADC?GH@DHDECI@IFIHFEIEB@BA?@BAGHIB?@B@?D?CAFIDF(DCAABA?CB
@>chr21:9540989-9541087-0
CTCATACCACGCTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTGTCACTGCCCATCTTGGGTGGCTGGTTGGGTGTGCTATCTGAG
+
BAB?AFIDECG@HDCCHH@HHIABHGG??DHIGHGCBE?F@B@A@I@GFCGBA?AD?@A!D@?DGGGCCEIHB5FIEG@CH?B@@GH@ACCCHDCBDAFB
@>chr21:9540989-9541087-1
CTCATACCACGCTGCACTGCGGGTGACCTGGGACGGGTTGGCAGCCCTATCTCAGGTGTCCCTGCCCATCTTGGGTGGCTGGTTGGGTGTGCTATCTGAG
+
HGIIF??EGDE@IHE?H?DFBDHBG*CADB?@?DEDIBAAD3DFAEB@ACG@@CCFAHEF:ECBG?@I?EAHE??D?D?FG@CGHEHEBC@CDAC?EA?F
@>chr21:9540989-9541087-2
CTCATACTACGCTGAACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTCTCACTNCCCATCTTGGGTGGCTGGTTGGGTGTGCTATCTGAG
+
@FHC?@C2A@CED@-DIH?ECEEGEBDFG@AEACBCEIBFCDFAAHEBH(CBGEEBF<@BHGD8@HECF?CDH?BAA@CDDCC@FIGF@HAFB?CCBGBE
@>chr21:9540989-9541087-3
CTCATACCACGCAGCACAGCCTCAGATAGCACACCCNACGAGCCGCCCAAGATGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACCC
+
?BCHABEH?I?H@BDEBDBHIFCGB?-?CFI@CCCE#?G)FB?I:GI@H@CHGA@GECDECFCC@IFHHHGHDDDBGFB?FIBEH??IGC?CH?FHHC@?
@>chr21:9540989-9541087-4
CTCATACCACGCAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGATGGGCAGTGACACCTGAGATAGGCCTCCCAACCCGTCCCAGACCACCC
+
ID?EA@DG?DHCADBFGGBAIGGA?CIHFG+DEAEB@HHCEEIDB@CBGDFID?I@DHAGF@AIFACC?CHGD@I-@I?A?DCADCDAEHCIE6GHHACA
@>chr21:9540989-9541087-5
CTCATACCACGCAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGATGGGCCGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACCC
+
AHH@DBEFB@GD?E@FFD@EHIFEGBHH??EIBB?BEBIF?CEGAACDC?ID@DAFB8?EGCIDAADAGEAGEBHEEA@E@B@H@I?DAFEDB@BB?CHD
@>chr21:9540989-9541087-0
GACGGTCCTCTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTGACACTGCCCGTCTTGGGTGGCTGGTTGGGTGTGCTATTTGAGGC
+
B@3@@IEFBDAIAFAAG@DC@GB@AIEFGGDCCD?EB?IBAEFDC??C@F?HBG@B<AAC@BC@IBBADHBDAG?DIBDE@FF?H@AA?IAD?&ABEHF@
@>chr21:9540989-9541087-1
GAAGGTCCTCTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTGTCACTGCCCATCTTGGGTGGCTGGTAGGGTGTGCTATCTGAGGC
+
BBEHGEB@@@ABDABFECBABHCC??E?HH?AGBIFIGHCAHHIDBDEHCGEDDGEE?HBCACICHGHF?@D@?E@@?EHE$HBHFIGF@FI@GD?A@BH
@>chr21:9540989-9541087-2
GAAGGTCCTGTGCACTGCGGGTGGCCTGGGACGGGTTGCGAGCCCTATCTCAGGTGTCACTGCCCATCTTGGGTGGCTGGTTGGGTGTGCTATCTGAGGC
+
IEGDH?DC@=ABHIIBC@AIGBHEEDFHBHBEBICIDF9DB??IIC?@EGIE@FI@I@H??GEC??HDIHGI@EDDBC?AFHBD@@EHFED@CI?IG@CF
@>chr21:9540989-9541087-3
GAAGGTCCTCAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGATGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACCCGC
+
HHGHBHFB@?CE?IEIDDA@F??AIE?@A@EEBCE?EICEFACDCGAHHEBBCEFGAIFGHEHGGC@DI?HGG@@F@GCBDDCIB?GCCH?IBBHIDHEH
@>chr21:9540989-9541087-4
GAAGGTCCTGAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGACGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACCCGC
+
FCB?DBIBI%HCAHEIF??BFHFCDDIIG@H?C?CGH@AHDEI??FC?C@DIDBA@H??GEGFFIDFAF?@A?FCGBCFF@E@GIH@@FGDCHDCAIFFF
@>chr21:9540989-9541087-5
GAAGGTCCTCAGCACAGCCTCAGATAGCACACCCAACCAGCAACCCAAGACGGGGAGNGACTCCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACCCGC
+
IDCHGF@HGGB@?GAHIHCBFC@F?IIDDGCHCADB?@@I?5@??EHGC@HGCA0CG$BFB"ACDI@HE@IFHFCHA@DBFG?@?GGFFIDDBA?A@FC?
@>chr21:9540989-9541087-0
GCGGCGTACTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCAATCTCAGGTGTCACTGCCCGTCTTGGGTGGCTGGTTGTGTGTGCTATCTGAGGCT
+
F@CGH?E@HA?IA@BIAHAG@CC@GADCA@GFFGIIDEH@HIIG=H?BAEABCE@CDDBHCFF?CA@DD@@C@GHFBEEHGB8DH@EAECDEBA?FD@EE
@>chr21:9540989-9541087-1
GCGTCGTACTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTGTCACTGCCCATCTTGGGTGACTGGTTGGGTGTNCTATCTGGGGCT
+
DHF6@HHAHCIAHIE@HDGDFAFDHDHG?DHF?FGBDHH@GFFB@AIIH?AE@@AGGGED@AGAHF?IFACFDC6DD@DFGCAEDH?4IHHACII0DFDE
@>chr21:9540989-9541087-2
GCGGCGTACTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTGTCAGTGCCCATCTTGGGTGACTGGTTGGGTGTGCTATCTGCGGCT
+
?IBDB?FGAIECHGHIEBI@BCDI?IHDHDHA@H@GIED?@IA?IH@FCD@DFIHEGD2?DE@DFD?BG?@FHH*GBBFHAAEBEI??E@DEFEC:C?FA
@>chr21:9540989-9541087-3
GCGGCGTACAGCCCAGCCTCAGATAGCACACCCAACCAGCCACCCAAGATGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCTCAGGCCACCCGCA
+
AHHHAHGDHCAA<FA?AEBHAIGG?GCIFDDD?GDIHCFB?CII@?E?FIFHHBBHIDAEFHFHEGEGDDDF@GFCGEEC@AFHEI=CEBDI?6@GF?AG
@>chr21:9540989-9541087-4
GCGGCGTACAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGACGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACCCGCA
+
BEDAA@?EADFHDF@B?HG@DIIIEDBDBG?GEBCIEA?DHA?EHHEF@FHBDB@GFCHHB@+E@CD@BIGB?DFH@?CEDHI??A?EBCFGGICHHEFH
@>chr21:9540989-9541087-5
GCGGCGTACAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGACGGGCAGTGACACCTNAGATAGGGCTCCCAACCCGTCCCAGGCNACCCGCA
+
??CFEE?H?D?A?AACH?EGFGI@E?H@@IEIEBF@I?CCH@HC?CBBHFC?GII@B?II=EGB=BG?ECEGECAFFF?EGEC@GFA@GEEF(C@@?@E@
@>chr21:9540989-9541087-0
TCAGACGGTAATCCGCACTGCGGGTGGCCTGGGACGGGATGGGAGCCCTATCTCAGGTGTCACTGCCCGTCTTGGGTGGCTGGTTGGGTGTGCTATCTGA
+
IG?CEHGBBACIG<HFEGIEI?A??GIEIAHFEFBBGF#?ICHDDBIHBG?EFIGCHH@A@?I@HHAEE?@A4HBIICAHCB?GAIIC?D?FFE?@F?G?
@>chr21:9540989-9541087-1
TCAGACGGTAATCTGCACTGCGGGNGGCCTGGGACGGGTTGGGAGCCCTATCTCAGGTGTCACTGCCCGTCTTGGGTGGCTGGTTGGGTGTGCTGTCTGA
+
G??CICH@@GEHFHAD??CDCIFB-GD@GEHIB@H?C?CD@BAFIDDE@BHE?AHBCBDCDDIEC?FEEEH?@IGAFF?AFIAGHFIEHEGGAE#AFCDH
@>chr21:9540989-9541087-2
TCAGACGGTGATCTGCACTGCGGGTGGCCTGGGACGGGTTGGGAGCCCTATCTCGGGTGTCACTGCCCGTCTTGGGTGGCTGGTTGGGTGTGCTATCTGA
+
HFFEIBIDE;GB?BEBG@DHGBGG?HFI?G?BB@?@BIGGC@GFDEGDIBCIIE"GFGG@HCA?D??IFBI@HCDAEGDAIBIHAGACEC?GAFHHH?EH
@>chr21:9540989-9541087-3
TCAGCCGGTAATCACCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGACGGGCAGTGACACCTGAGATAGGGCTCCCAACCCGTCCCAGGCCACC
+
I?AC*AEDDGE@GH2D@AHFCBFCAABIAIAAHEHE@BA@EII@DD@HIBFBADABHBDCACABDAC??IIDFHDG@BEICCFDGEBAFEEBFHA?FIDF
@>chr21:9540989-9541087-4
TCAGACGGTAATCAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGACGGGCAGTGCCACCGGAGATAGGGCTCCCAACCCGTCCCAGGCCAAC
+
@FGBE?CGED@B@CFAAFBGCHDHIGDA@C@CICA@EHAEGHHGIIGDIGC?H?IAIEAHF?!IH@I=?DGGHDIDHFAABDFC@BG???ABA@HBBH'I
@>chr21:9540989-9541087-5
TCAGACGGTAATCAGCACAGCCTCAGATAGCACACCCAACCAGCCACCCAAGACGGGCAGTGACACATGAGATAGGGCTACCAACCCGTCCAAGGCCACC
+
IGEAF@DIIHGEFCBGCG?GIDDF?DECIG?@D?H?7H@CHH@CH@@HIFGC@@CIBGBEDF@GHC4@@?CIFICGIE@=CIB?HIGBFFH>CCI?EAEF
@>chr21:9541125-9541219-0
ACCACTATGTCGGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTGCGCTATCCGGG
+
G?IBDGDBICG*FEIEH@BFAGEH@@FBE@EGII@BAH?CHIDF?HCHAGB??BFFEADCFIGI@ACGC@HHF@AAA??DDBHGI@E?A9BBF@GCCCAC
@>chr21:9541125-9541219-1
ACCACTATGTCTGCACTGCCTTTGGCGGGGCGCCGGCTGGGGGCANTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTNTGCTATCCGGG
+
??GF?HFD@BCCGCHBICE?C:?FA@ICGA(C@BDG0GHE?@FEB/@DEG?EB@@AF@FIGH?IEEECFHDFED@FGB?EEIHGBHD?'?A@EGEDHH?B
@>chr21:9541125-9541219-2
ACCACTATGTCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTAACCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTGTGCTATCCCGG
+
GFE?AIHBBAB?IADBH@I?AHFD@IAFH@EBED@CFCI@EFEEGICC.E@EDI@GEEBFGDD?DF?ABB@EA@C?IEFEGHBFG??HFG?FFCE?E-HA
@>chr21:9541125-9541219-3
ACCACTATGTCAGCCCCGGATAGCACACTTAGCCCACATCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCAGT
+
AA?CHDBE@GE?AI?BCIHIECAEBCHIHC?EGEIHC8AGIGFHB@?D@DFEAACAFG?BCCFHFAG@@FEFCHDG??BDH?ADBDDEEDICIEHD?DCB
@>chr21:9541125-9541219-4
ACCACTATGTCAGCCCCGGATAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCNGT
+
DBGFAI@B@BAHGEA?BG??G@@BAHAFICFGACADBE@HA?B?HBH@HAEFBABEEABHEHAFG?GH@HI?H@DF?BGBF??GGBAHGCEDB@CEI*IF
@>chr21:9541125-9541219-5
ACCACTATGTCAGCCCCGGATAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGCCTGGGATAGTGCCCCCAACCGGCTTNCCGCCAAAGGCAGT
+
B@B??HBCGFADHDGBIFEF@CI@AAD@ACDAEFAGAGHAHCF?I@?@@/G<DDE*B?H6BCEAAEHEGDHG?CCF@HCEB?EE$"@CG@?H?GHI@IGF
@>chr21:9541125-9541219-0
CTCATACCACGCTGCACTGCCTGCGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACGGTGAGGTGGGCTAAGTGTGCTATCCGG
+
AIGDB@AEFFABDAHDFAHBAF*:CHAGFAFEFGCDFE?EI?DC@?C?DEFCE@IHI@&BGAFHCIGBEF@D$DAGGBDHECADBAAHI?BIE?@@AG@C
@>chr21:9541125-9541219-1
CTCATACCACGCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTGTGCTATCCGG
+
AI@IGDHDFA??B?HDG@HIH?IEBAEDDACDGHC?@HHDGICHEGAGEHC@F?BBA5FIAH?EIFGCBIFFFE?CE@F?IIGB@@FBEIIFGIFHCD@D
@>chr21:9541125-9541219-2
CTCAAACCACGCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTGTGCTATCCGG
+
CE?B"AH@?BF?DFCEEHDEFH@FGBFADA@AH@IEI@CHFGG??HDGI@?GCHIGAABGDB@IGD@IACDBFGCB?IDEAGEDBDFHCD@GEEAE@GID
@>chr21:9541125-9541219-3
CTCATACCACGCAGCCCCGGATAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCAG
+
FE?IGAHCDGEIBH@HE?EI@HDDIC?ADFEBAII?CCBHG?@F?BFIHCEAAFC??EIFDH@@FH)GEDEIGB@DEHACCHFI@FE@EICGBHFD?BIF
@>chr21:9541125-9541219-4
ATCATACCACGCAGCCCCGGATAGCACACTCAGCGCACCTCACTGTTGCCAGCAATACCGTCGGGGATAGTGNCCNCAACCGGCTCCCCGCCAAAGGCAG
+
,G?ABHFHCAGC@EAD?HCBGBGFHDFG?D%FIF=CEG@D?I@BABEH@@?D?HI?CGAE@E7HAG?EAE?A*BB)D?BHGIEAHACFEE@I@GHED?CE
@>chr21:9541125-9541219-5
CTCATACCACGCTGCCCCGGATAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCAG
+
GIFCDBBGEEF@$IGABGEDHDEG?ID??F@GHG?GIIHBIEE@AF@@?HFHA?HAG@ED@FCGFDDGIGH?DD@GCHE?DDCCE@FIFHCAD?DGHA@H
@>chr21:9541125-9541219-0
GAAGGTCCTCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGCGCTAAGTGTGCTATCCGGGG
+
GFGFA@HFIBDAE@HFHDI?GEHDCIHBIDGFBBIFBFIIHDIFH??CBIG?FGHEHCFBCII@H@AH@I@HICGIC@?EHIDFC@?BAAHEIC@D@DCC
@>chr21:9541125-9541219-1
GAAGGTCCCCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAANAGTGAGGTGGGCTAAGTGTGCTNTCCGGGG
+
?B@CAIG@"CFI?CEHHC??FAIFIB@CHGICGA?C@IGBB@FBGCFFBCFBICCG@FBC?DFBHE@GE;A@IAEAB@DDBEIEGIFDH@DF0E?A?IDB
@>chr21:9541125-9541219-2
GAAGGNCNTCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGNGGTGGGCTAAGTGTGCTATCCGGGG
+
@FDEF%B3CAB?B@IDH@GHCDBGG@FGIABI@GHEAG?BHFAEBHIB?@FHCDDABAGH??FBEFHFDCBCA?6?HF@E@IHEFGIC?GAAE?EGIBA&
@>chr21:9541125-9541219-3
GAAGGTCCTCAGCCCCGGANAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCAGTG
+
AECG"HBFDDAIDGGCIIH7AIH@@?FI@EHBAABDH?BEBAAII?I?@H'ICGFCFADI@IEBIAFDEAG@CED?EEFEAH??DB@?D?@D?CEHED?G
@>chr21:9541125-9541219-4
GAAGGTCCTCAGCCCCGGATAGCACTCTTAGCGCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCACAGGTAGTG
+
?GAHADBGAI@@BGGIIBHBCIEAC4AEA??@@AEFGC?B@DCHBH@FCCDBEACFEGCDIFGCE?@BDH?H?CAB?CCBGBB?@CEE@@H(FC?=IHD?
@>chr21:9541125-9541219-5
GAAGGTCCTCAGCCCCGGATAGCACACTTAGCGCACCTCACTNTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGACAGTG
+
DDAAIDH@@GC??DIFHDBCIFFAEDFIABIEA@?IGF@CDI!IGF@?IBGCI@AHCEHIDCEE@DCGIIGDA?B?IHFG?H@C?II@?IGBIB%DHFFF
@>chr21:9541125-9541219-0
GCGGCGTACTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTGTGCTATCCGGGGC
+
EBBBIHHBB?DADCIIHAIIDABAHG?GAH?@?IHHGH-IIHBG@F?CADHDGEHIBH?HGEFDGFHCC@I@AGAGCBDDD@B?FF@FGDDIFBCAHED@
@>chr21:9541125-9541219-1
GCGGCGTACTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTGTGCTATCCGGGGC
+
IIHI?H?CCCC?EGIEAADA??@BCGEEGBGH@BABGCBC@E@BC?GBG?B?AAHE?AAA?FB@G@I@@BFEBFBB@?A?FDCFHFDFGHHEFHDH?CBC
@>chr21:9541125-9541219-2
GCGGCGTACTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGTGTGCTATCCGGGGC
+
HECEE?@GCFFB@BEHBIHIG?E@GHBIHEBDB?F@B@BD?BIEHAHA@@@EECGBFHCDGAE@?C@D@G?FBHBFEH?D@@DCHII???B@AGC?DGCG
@>chr21:9541125-9541219-3
GCGGCGTACAGCCCCGGATAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACGGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCAGTGC
+
?EIH@GH??ABGIDBFAIAF@H@FACGBEHABGBG@GCBFIEEFFE?DBFFGDG?8EHA?GDH@@HFHEIICEF@CEGBC@?FEADG?EC@D?IBHDH@F
@>chr21:9541125-9541219-4
GCGGCGTACAGCCCCGGATAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCAGTGC
+
GCIICBE?BE??AFIH??EBH?CF?E?A?IFDC@?E?EEFHB?DF@A@@HBDDGIFE@??FHFEEGH??G@IE@AACAGD@?IFIHBDAIDCGFIH@CB@
@>chr21:9541125-9541219-5
GCGGCGTACAGCCCCGGATAGCACACTTAGCCCACCTCACAGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCAGTGC
+
FD?AAIBDBICHAGFIIGADDIAIE@CGFDHB?EDEHEGI!A?FGECHIII?EH@@HEEB@I?@AA??FECGDFF?DGBDEDF?DDD?+?@ABE?ACCDG
@>chr21:9541125-9541219-0
TCAGACGGTAATCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTAGTGCTGGCAACAGTGAGGTGGGCTAAGTGTGCTATCCG
+
CGEEIA?I@HHGF?A@IF?D@AE@IFDAIDBEAGCGE?CBFHG@BCABAE?CICDHFHGFBB!??BDBCGCCH??DDFG??ADCGDEIEH?EDEH@HBEF
@>chr21:9541125-9541219-1
TCAGACGGTAATCTGCACTGCCTTTGGCGGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCAAAGTGTGCTATCCG
+
IG?CDFB?HADDEGFAGEE#BIE?HGEAHGBEA?CAF?E?B@IADHIFAEGHEBICBHE@ICBDEH@@A?IEDCEHBIA?HCGCC=FAEDBHDGFDI?EI
@>chr21:9541125-9541219-2
TCAGACGGTAATCTGCACTGCCTTTGGCAGGGAGCCGGTTGGGGGCACTATCCCAGACGGTATTGCTGGCAACAGTGAGGTGGGCTAAGCGTGCTATCCG
+
IDEIAA?BIFC?FGDAD@GDBIEFDF?H;?CAGA@HBFABGDE@A@AAEGEECGBBEADDIH@GGFGDIBHG?IAICBAFDC@@DEIEA&?GBHCBIHGI
@>chr21:9541125-9541219-3
TCAGTCGGTAATCAGCCCCGGATAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGGGCCCCCAACCGGCTCCCCGCCAAAGGCA
+
C@AE1H@EGDEB@BDAAGCI??@IB@H?D?FACDAFD@ABG?FHCDHEAIHEBE?@CHBFCCIDEFI@?AF.?HGADHEI@@H@?CF@DGBF@AFAIC@A
@>chr21:9541125-9541219-4
TCAGACGGTAATCAGCCCCGGATATCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGCCCCCAACCGGCTCCCCGCCAAAGGCA
+
?FIBHA@@GBCCFEBCFIA@BB?E<BFCCFGFHCHFIG@BIDIDIH?GFAIEBDIFGDCAGEA@CI@@?IEBICH@@E?CB?CDCICC@FBA?I@I@B?A
@>chr21:9541125-9541219-5
TCAGACGGTAATCAGCCCCGGGTAGCACACTTAGCCCACCTCACTGTTGCCAGCAATACCGTCTGGGATAGTGNCCCCAACCGGCTCCCCGCCAAAGGCA
+
DEBACIIB?CIB@IFAH@EG?%@EAIHCBD?BHIGAIAIGDEEFBCB@EAHH@@GBFBDFADGIHA@IBDIFA,BDE?@?B?AFAHF?@EHH?EFABABA
@>chr21:9541216-9541394-0
ACCACTATGTCTGCACTGTGCNGCTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGGAGGCGAGG
+
FI?H?DFHA??H@GHAAIEFC<@HFDD?F?FDE?IFA@EIDIHAI@GEIG@GCIBEI@GG?DEEDEAE@BCDC?IDIC?@EIA@FCAGAA@DHHAGA;AC
@>chr21:9541216-9541394-1
ACCACTATGTCTGCACTGTGCGGCTGTGGGGTGGGGGGTGGCTGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGNAGGCGGTG
+
EH??HDF?FDCCEDHG?DFCD@GAIIHF?II@?DHDII@BHE-G2EDB?ABC@@I@ED?A?F@BH?CDHECIDEFGBB@?CF?BFBCF?AI3@DF@GA#G
@>chr21:9541216-9541394-2
ACCACTATGTCTGCACTGTGCGGCTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGCGAGGCGGGG
+
BAGBF@D@D@HDBGAIHI@@AFIBD@DGE@DHCC?@?C@GCCAGIFDEIDDCICAHCAIEHCCEIDAFEFGC@I@CGEAHHBFIEGEFBH4FIEIF?B?D
@>chr21:9541216-9541394-3
ACCACTATGTCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACGCACCCTAACCGCC
+
EAD@HFGIADEEHDDF?HCDFAAFI@@FDEABHG@GAED"GDH??DHIHFA?BF?DCBGBDFHADC?BADHB?FHEAEBDA@HHBB9=?@@?GH?CFBBA
@>chr21:9541216-9541394-4
ACCACTATGTCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCTGCAGTGTCGCCCGCCGCANTAGCACACCCAACATACCCAAACCGCC
+
GF?AAHEADDHCHCAFIAACHA@CE@??AC6A??@FAEIIGEHEEE@HFGIH?<HGAF?@?BFGHE6A?@IA5CBAEIG@?EICE@?GGI?HCEHA?G?A
@>chr21:9541216-9541394-5
ACCACTATGNCAGCCCCTGATATGGCCCCCAAACCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCAAACCGCC
+
HII??@C@A3?EA?AGBFH@DDFBDEGEGB@G/CBFGDFGCG@A@D@???BAGAFHGD@?@EEB??IHDGF@EAHBBHFBAAH@H?C@EHEB@FH@@IEF
@>chr21:9541216-9541394-0
CTCATACCACGCTGCACTGTGCGGCTNTGGGGTGGGGGGTGGCAGTTCCGGGTTGGGGGCACTATGGGGTGCTGTANTGCCCATGGTGCGGGGAGGAGGG
+
EEFCC?HHA@BGDCBH?GEB@FE@CB:DFHA@?BAIC@FCBFBBHB@2DHIAEAE&@F?DBICDF@CDA@HFIBD?$@@IGH??EFCEAEFIAE?A'IEE
@>chr21:9541216-9541394-1
CTCATACCACGCTGCACTGTGGGGCTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGCGAGGCGGG
+
DBEG@FDFIDIGDBCCBG@EC5HFAGH@@AEIDI?FGDCIEH?IFHB?@BEDHE?GAECHIB?G@?AEABC@A@HBEHBDBBEADB@FDAG&HGCIEH@H
@>chr21:9541216-9541394-2
CTCATACCACGCTGTACTGTGCGGCTGTGGGGTGGGGGGTGGNAGTTTCGGGTTGAGGGCACTATGGGGTGCTGAAATGCCCATGGTGCGGGGAGGCGGG
+
F?@@ABGAGEDH@I,BIBH?BHDIH@B@AE+DCGABBBB@GI8FHAC@CFADE?I?BAADGF@@EBD@GEEFEB9DABG?EBFCDI?AHHDEDCBIBCII
@>chr21:9541216-9541394-3
CTCATACCACGCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCAAACCGC
+
FBI@GGBBABGGH@E?@BGHCBHIAGF@?HDHFHB?F?AEFFEC@AHBDF?@??DFD?G?C??FDF?CHID?C@CBHAHICCBFEA@DFFCDCEGBH@G@
@>chr21:9541216-9541394-4
CTCATACCACGCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCAAACCGC
+
A?EBDBDHFHHDAGG@HIBAHB?CCCHAI@F@HA@IE?BIEDDI@HDEABBACBB@GF?GI?@???CHBCAG?F?FB?DHCFDAEBG?HECB?HCH?@ED
@>chr21:9541216-9541394-5
CTCATACCACGCAGCCCGTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTTGCCCCCCGCAATNGCACACCCAACATACCCAAACCGC
+
AAFG?CDHGDIBIGBCF!FEBHIFADCDGEFBCG@FBFHHED@DFHF?H@DGEFCIBGA@@C#FDBHFCB@H?GG-?DIGCEBBEBGEBFIBDDD@GEGH
@>chr21:9541216-9541394-0
GAAGGTCCTCTGCACTGTGCGGCTGTGGGGTGGGGGGTGGCAGTTTCNGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGGAGGCGGGGC
+
?HDBCBDFFBE@FBHEAIGH??EDIHAHAFAIF@AFBCGIGAEADIF3FE@D?@GI?HGGICADDICEFEFFCGEHDEIH@DIIC?H@I@DBE@BBIIH@
@>chr21:9541216-9541394-1
GAAGGTCCTCTGCACTGTGCGGCTGTGGGGTGGGGGGTGGGAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATACCCATGGTGCGGGGAGGCGGGGC
+
@CC3EFCECDGHAI?GGBGEADCHB?HF?GE?B??CBB@H=AIIAIG?BGFHDEFEICC??G?AHIC?ECHCDBHA2ADCHF@?HBHAAIE?BFBEEAB?
@>chr21:9541216-9541394-2
GAAGGTCCTCTGCACTGTGCAGCTGTGGGGTAGGGGGTGGCAGTTTGGCGTTGAGGGCACTATGGGCTGCTGTAATGCCCATGGTGCGCGGAGGCGGGGC
+
@HD?GI@EDG?CFG@ABAIC+A@EIGF?ACI'DF?HIIH?BA@GH@*D+HHDIF@DDB@@GHEI@H.?FAEEBAFAEFE@BEHCD?E?1AE@?IDAEAA?
@>chr21:9541216-9541394-3
GAAGGTCCTCAGACCCTCATATGGCCCCCAACCCATGCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCAAACCGCCC
+
BEBHBA?I??BH&BH?A3AH@ECGIBDBIAI?HIBA&GF?GCG?DEIBI?FDG?BHDIE@D@BF?EAEEGICAAAE?DFADC?IGF?@FH?AII?HF?EH
@>chr21:9541216-9541394-4
GAAGGTCCTCAGCCCCTGATATGGCCCCCAACCCATCCTGCACCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCAAACCGCCC
+
CD?@G@DD@C?HFA?BEGDGICDAHCEICBFEDF?IDCFCD-A@BAECEIIFHBBHE?BBE?IC?AGDHHEHBACHD@?D@DACAAIF@DDIIFIB@D?@
@>chr21:9541216-9541394-5
GAAGGTCCTCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCTCCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCAAACCGCCC
+
G@E.HFBEB@DI?HEIEFBGBE??BA@FHIFGEEIDFAGBIHCHHFABE0HG?D@HFCHE@B%@@BBH<@B@EIFEBGHB?AFC?DED@FCFBHEEDEIA
@>chr21:9541216-9541394-0
GCGGCGTACTGCACTGTGCGGCTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGGAGGCGGGGCG
+
EDFF?IHCGBIGHCICCEFIDFI?GFFBBFHDH?I?CB?DFGHC?FFEF?HHEEFIGGCDEFIEIHE?A?HH?F?DCIC@CBDAFBAGBAG@FCGC?FCB
@>chr21:9541216-9541394-1
GCGGCGTACTGCACTGTACGGCTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCTATGGTGCGGGGAGGCGGGGCG
+
@C?D?AHDD@D?DDFDB!ICCAFAHHIFD@@HIF?$DBACAGBC@C@@BGH?GIGDIHC@GEGF@?C@@BHHDFDDG@.AHAC@DHHFC?DD@EECGHHG
@>chr21:9541216-9541394-2
GCGGCGTACTGCACTGTGCGGCTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGGAGGCGGGGCG
+
CGDCF@DFF?GCC@FEFFFD@C?D.AICHEG?BGAIIE?ACFD@EIG?CBBGECDBFDGEFDDGEHD?IFGH??@?IIBHBE@@DHF@BB?H@GCF@EBG
@>chr21:9541216-9541394-3
GCGGCGTACAGGCCCTGATATGGCCCCCAACCCATCCTGCCNCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCTAACCGCCCC
+
?CIGDC@FICG'AEEBBCBIFDGFAEEGAEGFFBGGD?FD@)@BGAHHBDFFIBDHBEIBEIEGCA@?IADAC?FECABCBCHEFIIAICECCHE?@CDE
@>chr21:9541216-9541394-4
GCGGCGTACAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCTAACCGCCCC
+
IGHDI@A@BGEAD@DHADFIBCDEADDACCACI@?DHEAC?I??EAAFBDBIB?DFDBBB@FHBCBBFEE?FBGDBB?AH?BBGB?GDHFHG@HIEAEB?
@>chr21:9541216-9541394-5
GCGGCGTGCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCTCTCCGCCCA
+
?AFG?EB9BAFGE?ECI?HBAFAD?EC@BG?BCHG?@CEDEA?H@I?ADABA@EG?GDCHFDCDEB@FIGHGHCDBG?ABAGAG?G@?EAG);A??HAA3
@>chr21:9541216-9541394-0
TCAGACGGTAATCTGCACTGTGCGGTTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGGAGGCGG
+
IBDDIHICEAG@IB?CA?G?EBIIC8B@AIA?AFBFI@IDAFBDHDABCHCGA?EDI?ICG@@E?CHEDEFFBHEA@AIBABFAA?GBE?BCCACBCE@I
@>chr21:9541216-9541394-1
TGAGACGGTAATCTGCACTGTGCGACTGTGGGGTGGGGGGTGGCAGTTTCGGGTTGAGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGGAGGCGG
+
A;AIF@FHBAGC@ADFCADCHBFC8FCDD?CFF@ADIBHDGI?EHCDHDCC@GIGDIBB?@?EAFBAFF@EIGGB?@GIDHCEGHDBIF?BICC?H@H@B
@>chr21:9541216-9541394-2
TCAGACGGTAATCTGCACTGTGCGGCTGTGGCGTGGGGGGTGGCAGTTTCGGGTTGTGGGCACTATGGGGTGCTGTAATGCCCATGGTGCGGGGAGGCGG
+
ICHC@AIAEIDI@?FDEGFBIEDDE1DHCID=BF@DABID@GC?D@A@CHIAFIDD$IDCHIE@FBCHGEHABIEG?@EG@@GHBGBICCBG@IGD@BAF
@>chr21:9541216-9541394-3
TCAGACGGTAATCAGCCCCTGATAGGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCCCCCCCCGCAATAGNACACCCAACATACCCTAACCG
+
GEABD?@HHECF?IG@EBAIDFDA=?BHFD?AEGBCD?@I@BGBED@FBEBCE@EGCBIDD(F@!ECDCDGFACHCEC<DCBDDCEDFE?DDHEGA?CDA
@>chr21:9541216-9541394-4
TCAGACGGTAATCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCACACCCAACATACCCTAACCG
+
F@EGCBACHDFADDDFB?I@BIDADGFAEBIDHCIEBHIC??@E@?BGADBFDCD?IFBHBF@IHACBGBCBACFA@BB??BDDGH@GFFGFIHBIIGAH
@>chr21:9541216-9541394-5
TCAGACGGTAATCAGCCCCTGATATGGCCCCCAACCCATCCTGCCCCCTACCACCAGCAGTGTCGCCCCCCGCAATAGCAAACCCAACATACCCTAACCG
+
GADBDF@IAGIH?@FB?IGGCBCCGF?D?CAHIB@BG@DHFA?HDFGC?DACFFCEFA@@?GFC@CHEI@HGF@?@DIEB5IHAF@FBCIACGIDFFFDE
@>chr21:9542767-9542841-0
ACCACTATGTCTGCGGGGTGCTAGAGCCTGCGGCCCACTGGCTTGAATCACTGTGGTTGGTGGTGGCGGTAACAGAGACTGCAGAGATCGAAAGAGCGAA
+
BBIIDAIEEH?@IG"?CI?@G@G@AEF@?HGIAFD?@GHEAI@?D:;@B0FGHG?DIHFE@G?FDGEBFFFFBCA?H?@CGCFGBGC?C?>EGAIBCFC@
@>chr21:9542767-9542841-1
ACCACTATCTCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGGTGGTGGCGGTAACAGAGACTGCAGACATCGGAAGACCGAA
+
GHHEIAFC*FEAFBIEE?HFIFCIIBGBCH??AFHGABBAFEFED@?@H@B@FDBCIGBHGHFIH@DA@AEIID?HIHHBCCFED.EHIIEHHHA#HG?H
@>chr21:9542767-9542841-2
ACCACTATGTCTGCTGGGTGCTAGAGCCTGCGGCCCACTTGCTTGCCTCACTGTGGTGGGTGGTGGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGAA
+
CFHIEFH@HHBIFE@BBE@AEF@EBBA@ADH?&@HGC@E9F@?GCEHFA@HC@B@BD/@FEHGF?ACBIDHBG@BGICCCBIBHGAAA@DG@?IFEEHAE
@>chr21:9542767-9542841-3
ACCACTTTGTCTGCAGTCTCTGTTACCGCCACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCGAA
+
B@DE?I:BDC@DFFCBACBAGBCBII@@CGEBDICBHGFGICADCHE@FDHH@@?FEFA@HGDAHHHAEGAB@@EH?FBDEBG?DAA@C?HBIG@@BFAB
@>chr21:9542767-9542841-4
ACCACTATGTCTGCAGTCTCTGTTACCGGCACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCGAA
+
?EAD?EIDFCDCHIIFGAGBDBDAA@I?=DHBB?HBBHAIGGEF@FD?GB@CCEGBH?BA?HGBCBGEBBCIEIDDHE?EHAA?HF?GHHI?BCBCHG@I
@>chr21:9542767-9542841-5
ACCGCTATGTCTGCAGTCTCTGTTANCGCCACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCAGAAGAGCGAA
+
E?@-ACIB?I?FEAFFEICG@ID?@7DCGHB?ABIEAHCIE@FIGFCFAADFAHECA@IGG?GBCGIAI?F?GCC?EIB@AFBE?C@BI9HGHEGCCCDC
@>chr21:9542767-9542841-0
CTCATACAACGCTGCTGGGGGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGGTGGTGGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGA
+
EBICA@F4EGAD?@FFF@A:DD?G?@B@FBADDE?BC@FFACACI@F@ABHDD?GHH@HAGBF?AEGBGA@EGFADIB=FFDBIIEBFGEGBGEDFCFGC
@>chr21:9542767-9542841-1
CTCATACCACGCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGGTGGTGGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGA
+
B@FA@E?AEA@ADAFGDEIEEAFH??FICABCEHGAG@?AEF@?HHHB@EDG??GEEFIACGGBHH?DAGFAEDF@C@CGA?HDBHDDG@DC?GBCACFG
@>chr21:9542767-9542841-2
CTCATACCACGCTGCTGGGTCCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTAGTTGGTGGTGGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGA
+
G@??FG?BCG@GFB@DHIAH3EH?4C@?FHFGH?CECCAAFBI?G@GABCCAE@E:EGEHBGC@I@B??FF?EFHIACD?DADFIHAB@?HCICAIIH&E
@>chr21:9542767-9542841-3
CTCATACCACGCTGCAGTCTCTGTTACCGCCACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCGA
+
@BI@BEH@@HEGC@C?AHCBFHE?EEA?HCBIGH@GAAAEGFB?FEHD??@GEIII@HGDFEIFCDDB@IAIHFIEHI@AGCCB?HHB@HIC?GIAD@@F
@>chr21:9542767-9542841-4
CTCATACCACGCTNCAGTCTCGGTTACCGCCACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCGA
+
CBFIFA@BCHB?H#BCCCHCF.DGII@DHFH?FC?EH?FGEH?D@CHGGG?AC@HC??EFIEDCEIDGBGGEDDIAC?@?HDEGDGAGDGICA@BFFDBA
@>chr21:9542767-9542841-5
CTCATACCACTCTGCAGTCTCTGTTACCGCCACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCGA
+
GG?EA@GCCH1GDF?HHBDIDGHIGEA?E?CCEI@FCHGAIGF@A?FEFHIFEF@CAH@H?ECBCFGEFFEIDIHC?CHIHGHHAEADEICBFGAHEAC?
@>chr21:9542767-9542841-0
GAAGGTCCTCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGGTGGTCGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGAGA
+
?I@AFBIGHBFHEHH@IAFBAFDE?BF?DIF?EA@DABAA?@E?FFCD?DCCEIICCGABDDCI?@FDH?GGH@BHI?GC?B?BCI@CIDBDD@FB??5F
@>chr21:9542767-9542841-1
GAAGGTCCTCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACGGTGGTTGGTGGTCGCGGTAACAGNGACTGCAGAGATCGGAAGAGCGAAA
+
CEBABDEGDGADCHFA?AIHFIC@FDD@CCAFBAG!?AA?AD?HDDFIDI:HGGAAB@B@DF?ICBFBGEGHGD;GBDACDEBFB?EAGHHAEIHAGE@E
@>chr21:9542767-9542841-2
GAAGGTCCTCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGGTGGTCGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGAAA
+
CHGGHDGBHGDGCI@??EB?HHIGCIED?I?BAA?EHI@GBBBG@EIFE@FG@F@GFFIGGHBBEFFEC@CH@AIID@IDDEIDGI?CAFEBBD?@?FHG
@>chr21:9542767-9542841-3
GAAGGTCCTCTGCACTCTCTGTTAACGCGACCACCAACCTCAGTGAGGCAAGCCGGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCGAAA
+
DIAI@I?AEF@IB?;EECI?IFCD9FFIIGI?IBAACFC;@HCEFIBAHAGGG@5I?C@@IBI@HGEEIFCFGIBIBCCECHA?AICGECDE=GACDGCE
@>chr21:9542767-9542841-4
GAAGGTCCTCTGCAGTCTCTGTTACCGCGACCACNAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACNCAGCAGAGATCGGAAGAGCGAAA
+
GGFD?@HDDAEI?CH?CIA@@EDDE@CICA?CBE:AGD?C???B@DAHFCEGFC?D@FC@@?@@BDIED@GFCH@G#G?GEA@GF?CA?ABHF@HGAFG?
@>chr21:9542767-9542841-5
GAAGGTCCTCTGCAGTCTCTGTTACCGCGACCACCAACCACAGCGAGGCAAGCCAGTGGGCCGCAGGCGCTAGCACCCAGCCGAGATCGGAAGTGCGAAA
+
FDIGHAC@CID??CHHIFHAGII?IC?CE?I?EG@?FCG@@HC5@DGFH@IHIEAEDDFD?GDAE@@H6?HH?CEB?F?BG=D?IAGBIEFCH6F?AC@F
@>chr21:9542767-9542841-0
GNGGCGTACTGCTGGGTGCTAGAGCCTGCGGCCCAGTGGCTTGCCTCANTGTGGTTGGTGGTCGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGAAAA
+
H4GFGHE?E@IB@A@ICIIFDBCHBHFBDEC@BAG#??F?CGCBCGEF7FEB?GBEHI?ABCBB?@A@DDCHBGAGHBH?EGAIEB@GFBIC@?GI?A?D
@>chr21:9542767-9542841-1
GCGGCGTACTGCTGGGTGCTAGAGCCTGCGGCCAACTGGCTTGCCTCACTGTGGTTGGTGGTGGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGAAAA
+
A?I@@?DBBGF?EH@?DHFACCCI?HA?F@ABF'@?@IEEIICIHIGGDEDC?BCAHFBHD?FCIDICHCBD@FEAEBFBFB?DC?E?I?DCF?G@CCAH
@>chr21:9542767-9542841-2
GCGGCGTACTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGGTGGTGGCGGTAACAGAGACTGCAGAGATCGGAAGAGCGAAAA
+
FECFHCCGCFEEGH?IAD@EEBFE@IICCBE?AFIF@E?@A?FDEHDFAADI?EEFFIFGGBEFIIHDDCHFHEHG?I?DB?DCE@GAGCDEBDEEI@CB
@>chr21:9542767-9542841-3
GCGGCGTACTGCAGTCTCTGTTACCGCCACCACCAACCACAGTGAGGCAAGCCAGTAGGCCGCAGGCTCTAGCACCTAGCAGAGATCGGAAGAGCGAAAA
+
GBFHIH@BECDIE?@DGHGFHD?EAI@FAD@EFGHEBAEDGBBBDH?HE?HGCCF?4EDCG@?HDCBBDIEBBDF?1EEIID@HBF@@FCCECIICDGID
@>chr21:9542767-9542841-4
GCCGCGTACTGCAGTCTCTGTTACCGCGACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCTGAAGAGCGAAAA
+
FE'GBGACF?@IGF@AE&BBDCA?ICIH?GIGHDD@HIHCI?EBDBE@FHBHE?ADGCDGBDHHCDB@GA?GEEF??FIIGA@F?EB#@IDIAAFFIEH?
@>chr21:9542767-9542841-5
GCGGCGTACTGCAGTCTCTGTTACCGCGACCACCAACCACAGTGAGGCAAGCCAGTNGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCGTAAA
+
?@GEHEHIIBBG@BF?HHGCIBGBFAICE@EH@HHAIBH@?D@G?EECCIEA@IE15G?FDBFDAGCBA?GDDBBEBGGDAACC?@CIIEHAEFHD9BDD
@>chr21:9542767-9542841-0
TCGGACGGTAATCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTNGCCTCACTGTGGTTGGTGGTCGGGGTAACAGAGACTGCAGAGATCGGAAGAGCG
+
G?5BIG@G@CAEH@D@FIB@IDHHGDCB?DAGE@@DDCBDCGGB@#DFDEC@ADAFEC@AFEIDHADG8ECHCABHAGEHBFDI@ID@IFDAFEB?DFHH
@>chr21:9542767-9542841-1
TCAGACGGTATTCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGCTGGTCGCGGTAACAGAGACTGCAGATATTGGAAGAGCG
+
@GBAADIDBC7GG?GE?BBEBCECIBAH?HGHGECG??BAGI?G?DFGGC@BAB?GGBGIF!HI@HDC?AAHCDIDC?DGHHB@?IB&EI>G?CFBF@HD
@>chr21:9542767-9542841-2
TCAGACGGTATTCTGCTGGGTGCTAGAGCCTGCGGCCCACTGGCTTGCCTCACTGTGGTTGGTGGTCGCGGTAACAGAGACTGCAGAGATCGGAAGAGCG
+
B@EGCA??AA!BFIFACDI@@ABGCEG@A@ABI?@EDGCID@?@>IBBGHEFDEBBFGHDC?GD?ADIDDEBCADBCAGGACA@?BCCAF@D?HHEFHAC
@>chr21:9542767-9542841-3
TCAGACGGTAATCTGCAGTNTCTGTTACCGCGACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCANCCAGCAGANATCGGAAGAGCG
+
EBBBCEFBAFDD?B@CEII=BI?BGIEBHIA@BDH@@EEIACFDEFCBFICGH(BHFI?EEHFCEGIADDB@?HBIE?>CCHFGCHF#CGFDG?B@?G@F
@>chr21:9542767-9542841-4
TCAGACGGTAATCTGCAGTCTCTGTTACCGCGACCACCAACCACAGTGAGGCAAGCCAGTGGGCCGCAGGCTCTAGCACCCAGCAGAGATCGGAAGAGCG
+
?FFCF@DAHB?BEA@@?@GDDIDGCFF@@BIHICBFIIDCEIHIG?GEAFECB?CIBB@AGFIHBGF@DGEIHBFCCGFEG?@I?HGDF@?AGBCFBFCD
@>chr21:9542767-9542841-5
TCAGACGGTAATCTGCAGTCTCTGTTACCGCGACCACCAACCACAGTGACGCAAGCCAGTGGTCCGCAGGCTCTATCACCCAGCAGAGATCGGAAGAGCN
+
C@FAB@IIICCFIGDHEH@@BAAEHE?AIAIAFAB@EEAAIGEHHGIH?&BCHBA?FAH@GA,EG@?GABHBHCF;EAE?@@A?EBFIDGGEBCEII?I/
@>chr21:9542876-9542970-0
ACCACTATGTCTGCACCTTTCGCAGTGNGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGCGTTAGGGGTACTGGTTGGTAGCACTCCACAGG
+
GE?HIDF??IGBEA@AG@E??BGG?AF4GHE?FHEIFCDDDEDFAF@HFAH?CGEEACHIAIIIECI?DECGH??F@GADACHFCAGFC@FIHIDAHDGH
@>chr21:9542876-9542970-1
ACCACTATTTCTGCACCTGTCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGCATTAGGGGTACTGGTTGGTAGCACTCCACAGG
+
GACDH?;B%??EIGBDIE;DGC@GBCA?FBH?DCAD?C?FFCBGG@?DGE@EH?AEC?AGAI?H?FI@AFFAHG@?@ACGAIGAGCB@HIAFIDFEHCFH
@>chr21:9542876-9542970-2
ACCACTATGTCTGCACCTTTCGCAGTGTGGGGTGGGTTGTGGGCGCTATCCAGGGTGTCATTGCCTGCATTAGGGGTACTGGTTGGTAGCACTCCACAGG
+
??AEIF@CHIGEIHCCHGBIBAGGEBE2?FHEA@FBHAD%AFD?EHHI@GF@@GFADFEHAC@@HAEAAAHFFI?FGEI?AEAG?AEC@C?EHCGFI@II
@>chr21:9542876-9542970-3
ACCACTATGTCAGCCNTGTGGAGTGCTACCAACCAGTACCCCTAATGCAGGCAATGACACCCTGGATAGTGCCCCCAACCCACCCCACACTGCGAAAGGT
+
I?AECGGHIDECDD@<EHA?GE?EDCBFCABHDGFAIA@DC@@IHDG@BAF?AED??BBCEGIAECHBB(?B?IBGBHA@C@GEAECF?IE?BH@DAGAG
@>chr21:9542876-9542970-4
ACCACTATGTCAGCCCTGTGGAGTGCTACCAAGCAGTACCCCTAATGCAGGCAATGACACCCTGGATAGCGCCCCCAACCCACCCCACACTGCGAAAGGT
+
C?GH?F@@BICDCBABBIGIIG@AFDEIGFDC:A?HEDFGCIFB@!CIDHBECCGDG@CDGEBEDA@ICBHABACAA?FAIHGAE@2IAGFEHE@IFA?F
@>chr21:9542876-9542970-5
ACCACTATGTCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAACGCAGGCAATGACACCTTGGATACCGCCCCCAACCCACCTCACACTGCGAAAGGT
+
IH@EIHBDICIFCEACBFHEAIBBBBEDBDB@IF@CHE@CCDGEBFHCGHCICFCAI?E@B6?D@GDE'CBDE%@GGDEHEFDH0DBIGGBDHFIFACGI
@>chr21:9542876-9542970-0
CTCATACCACGCTGCACCTTTCGCAGTGTGGCGTGGGTTGGGGGCGCTATCCAGGGTGTCATAGCCTGCATTAGGGGTACTGGTTGGTAGCACTCCACAG
+
FCHDC??ICIGAICGH@IAG@IEIAHHFBE?(DFAF@A?@@H@GI@FIGHDCBCAFE@?GDA7B?HCHBCAHEC?HIE@FFFDHE@@@?H@GGDIAB?HB
@>chr21:9542876-9542970-1
CTCATACCACGCTGCACCTTTCGCAGTGTGGGGTGGGTTGGGGGCGCTACCCAGGGTGTCATTGCCTGCATTAGGGGTACTGGTTGGTAGCACTCCACAG
+
@B?CC?@AGGA@G?GI?CGABDGDHFDB?@FA?DAB??ABIE@@BBAFC!CC;AEDA@GC?FE@AE@@GECA?AHBAEEHBFEHGAAFA?IAEAGFAF@@
@>chr21:9542876-9542970-2
CTCATACCACGCTGCACCTTTCGCAGTGTGGGGTGGGATGGGGGCGCTATCCAGGGTGTCATTGCCTGCATTAGGCGTACTGGTTGGTAGCACTCCACAG
+
IA?@EA?FFBHHBBGHDA??FEAHGG@DFFC@E@CIF=BEGG?EDFBCBDDFGIGDICAEAEBFDEH@EBIGCBD6A@C?DCFC@??AEFAEGECC?DB?
@>chr21:9542876-9542970-3
CTCATAACACGCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAATGCAGGCAATGACACCCTGGATAGCGCCCCCAACCCACCCCACACTGCGAAAGG
+
EFHEFE#I@FIFBB??A@AAHBBFC@EGFAA?FDECCHF?E@BIFGBHBFIBEHGCBCHCGDGFIF?DABI?@@CCFAGDE@ICBH@??IF?@AEDHFAH
@>chr21:9542876-9542970-4
CTCATACCACGCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAATGCAGGCAACGACACCCTGGATAGCGCCCCCAACCCACCCCACACTGCGAAAGG
+
GHGICFDIDIBH@HDAH@@@IHIEAACB?BDDHBIBGHA?HCBCDACDB@BFDB?1BAGABIFBAEB?@CFDFBCHAA?D?EB@?FFCABCBHICFGH?B
@>chr21:9542876-9542970-5
CTCATACCACGCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAATGCAGGCAATGACACCCTGGATAGCGCCCCCAACCCACCCCACTCTGCGAAAGG
+
A?GH?FGCBAIHC?ICECBI@IC@IF?DGCFD?IEDGCABAFIIFBABGDIFHIG?ECBGIFD@E?BGCGFHFB?AG??HEAGID@C?C4GA@BHAGAIH
@>chr21:9542876-9542970-0
GAAGGTCCTCTGCACCTTTCGCAGTGTGGGGTGGGATGGGGGCGCTANCCAGGGTGTCATTGCCTGCGTTAGGGGTACTGGTTGGTAGCACTCCACAGGG
+
CG?GGB@AHFCFDIC?A?HCCG@BH?EF@ABE?BA:GFGI?EBGGCI'AFAF@@HGFDC@EAEFADHEABFF?E?DAIDGBGIAABBE@CIGCD??D@A'
@>chr21:9542876-9542970-1
GAAGGTCCTCTGCACCTTTCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGCGTTAGGGGTACTGGTTGGTAGCACTCCACAGGG
+
CBFC@@DCFI?GH?GFH?GAEBBI?EDEFG@?CD@GDDAFHGFFBFCEHFI@I?DIADGABHAFFDGAG?GII@B??IIIIA?IHHFEG?CHDG?IFHIA
@>chr21:9542876-9542970-2
GAAGGTCCTCTGCACCTTTCGNAGTGTGGTGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGCGTTAGGGGTACTGGTTGGTAGCACTCCACAGGG
+
EDIDFDAEI@EEGHI?CBH@C)ID@CFB?!AIAHGDBDIGCEFDIDEEIBAIHAGGEBACCIBHHIAADH@FBHHEDA@A?HFBE@ABF?HBACAGBE@G
@>chr21:9542876-9542970-3
GAAGGTCCTCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAACGCAGGCAATGACACCCTNGATAGCGCCCCCAACCCACCCCACACTGCGAAAGGTG
+
?@HH@DFI?FEA?A@BCIEGCDFDF@D@AHF@BFD@?HB?IHA@HHDF@DBEAHEFDGFGAF3DBADFI@CCEGHECFDDHF@HE@@?B?G@DF@?ICFI
@>chr21:9542876-9542970-4
GAAGGTCCTCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAACGCAGGCAATGACACCCTGGATAGCGCCCCCAACCCACCCCACACTGCNAAAGGTG
+
I?@BGHBGBIA?@@DADHBHBHGFF@IF@C@C@C?CADGB?HGD?HB@H??BB?F@?BE?CIDDHD@ABCCB?FGFBAAGIBCIICF?IIGI0E@DG?H?
@>chr21:9542876-9542970-5
GAAGGTCCTCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAACGCAGGCAATGACACCCTGGATAGGGCCCCCAACCCACCCCACACTGCGAAAGGTG
+
GHFEAI@ADB?I??HHGHDBCDC?CGFCIBBADFIA@?HAEG@DH@HAFDHI@EECA?@DEIHBEDGE>EGBCC?G?CFFIC@AFGIEE?D@DCBFHFEA
@>chr21:9542876-9542970-0
GCGGCGTACTGCACCTATCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGCATTAGGGGTACTGGTTGGTAGCACTCAACAGGGC
+
FAEBFDFADCFIIHE@6IDD?FIDF@EFDHECHHDDIDEAD@AH@H?AACGBG??AD?CFHBGGGA@?DIFEC@D@EG@ECI?AE@EFFEAE)FGCFFB?
@>chr21:9542876-9542970-1
GCGGCGTACTGCACCTTTCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGCATTAGGGGTACTGGTTGGTAGCACTCCACAGGGC
+
HBEEI?FCFBIBBD?FH@CFGDHADI?BC@IEAEICDG@HE?E@HCAHC@??DC?A?EAHB??FED@D?GEEDIIH@?IEF@BHFCEE?GFB?CCDIBG?
@>chr21:9542876-9542970-2
GCGGCGTACTGCACCTTTCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCGTGCATTAGGGGTACTGGTTGGTAGCACTCCACACGGC
+
FACCFEACCADAFAGCE@ADHDGD?CACFFBDHG?BFIBG@BGEGFBDGHGDEHGFDBGECD(I?EB@IDC@DHAEI?D@ECHBFGCE?@HDIBCA.@GF
@>chr21:9542876-9542970-3
GCGGCGTACAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAATGCAGGCAATGACACCCTGGATAGCGCCCCCAACGCACCCCACACTGCGAAAGGTGC
+
ECCHEDAFGAA@DHFDAH?GICGCAHHCIDAA@FIGIHIFEA@BCAEA?C@EIEHF@?CGFGGGBDEIGEHA@ABH?/GDI@?EGGHDCA?DDIII?AHI
@>chr21:9542876-9542970-4
GCGGCGTACAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAATGCAGGCAATGACACCCTGGATAGCGCCCCCAACCCACCCCACACTGCGAAAGGTGC
+
BABFGDFHHHE@GGDBCFBBH@ECGEDBGEHF??CB@DADBD@HEECHIEAFBFIGHDAHAIBAIEEGDBAB?EGBGI@GI@BF?FHGEDD?AFBDFAA@
@>chr21:9542876-9542970-5
GCGGCGTACAGCCGTGTGGGGTGCTACCAACCAGTACCCCTAATGCATGCAATGACACCCTGGATAGCGCCCCCAACCCACCCCACACTGCGAAAGGTGC
+
EBHBIC@HAI?I?/FD@HA"@DIAB@FEIEDFHD?A@HEHGCGBBB@/GE@GBCG?@BDAHBGCH?IC@BID@DCGBEIBGI?B@@FAAFA@IIB@FA?D
@>chr21:9542876-9542970-0
TCAGACGGTAATCTGCACCTTTCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGGGTTAGGGGTACTGGTTGGTAGCACTCCACA
+
?@?HEBGBCA@DBEHDECDAADICHDFGGACGHABAACDAAICB?@@HBCFDHD@?II@DEBAE@E@FG2HC@A?@GDHBFABHIEBEBFIDHHI?I@?H
@>chr21:9542876-9542970-1
TCAGACGGTAATCTGCACCTTTCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATTGCCTGCATTAGGGNTACTGGTTGGTAGCACTCCACA
+
D?CBHIC1?EEBIDEBAFBAECIIFIHE?@IAIICEDGC@@GAGCF@BAIFHDIBC@H?@GCCC@HIEGCD?BAFAD7I?GGDHDEB?GIHIEFFBEACA
@>chr21:9542876-9542970-2
TCAGACGGTAATCTGCACCTTTCGCAGTGTGGGGTGGGTTGGGGGCGCTATCCAGGGTGTCATNGCCTGCATTAGGGGTACTGGTTGGTAGCACTCCACA
+
H?ED?H?GFI@ACBCBFBDBFHGI@DI?FBDECD@EEGA@G?CAE?GEC@EC?FBAIGEI@FE7EGCA@FCI?@HACGGC@DDGGCI?FEHCI@CH?F?B
@>chr21:9542876-9542970-3
TCAGACGGTAATCAGCCCTGTGGAGTGCTACCAACCAGTACCCCTAATGCAGGCAATGACACCCTGGATAGCGCCCCCAACCCACCCCACACTGCGAANG
+
CCF@AAHHEHAED?IC?BIGA@@D@?HFCDBAC?FFC@A???GIAD@AGDEGIF@@HFEEIIAAFFI???F@DHGI?DFIAEDFHAG@A@DGGFCHI?>C
@>chr21:9542876-9542970-4
TCAGACGGTAATCAGCCCAGTGGAGTGCTACCTACCCGTACCCCTAACGCAGGCAATGACACCCAGGATAGCGCCCCCAACCCACCCCACACTGCGAAAG
+
GH?AEBDEIICCIEC?IG*?I@C?EGAICCHG.C@I.GIGCAGBIC@B???BDFD@C@EGCDHC.EFD?G?@CFGDDA?E?AIG@IE?HAIABIB@BCGA
@>chr21:9542876-9542970-5
TCAGACGGTAATCAACCCTGTGGAGTGCTACCAACCAGTACCCCTAACGCAGGCAATGACACCTTGGATAGCGCCCCCAACCCACCCCACACTGCGAAAG
+
GIIIFIAGHEHBAI(BBCCGD@BEAABGDDC@IDGGIICFICGBAGHG@1CC?AIIEGF@GCC0I?BGH@DEHD??DAIB@@IAGCE?BD@IBB@@FFI?
@>chr21:9543014-9543154-0
ACCACTATGTCTGCAACGCCCATCGAGGAGGTCAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGGAGGTGGGGGGCGCTATTGA
+
IIABF?DDE?GIABCI7IEFHAF4EHFDB@E-CHCDEHEGDFII@DDABB@?IIAFFDDHA?H?HG@DIFBEEII@?C?F?AG@I#IFFFDFFAHIC@??
@>chr21:9543014-9543154-1
ACCACTATGTCTGCAATGCCCATGGAGGAGGATAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGGAGGTGGGGGGCGCTATTGA
+
@BH@?HFEAGFGCAAFHFBFDFGHAEHDHBG@,CFH@BCBA@IG@H@GIFECGIEBIFHHIEAIFDDICFA@GAI?FCIIGIAD@AHG@BECGEIFC?DF
@>chr21:9543014-9543154-2
ACCACTATGTCGGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCGTTGGGGGACGGAGGTGGGGGGCGCTATTGA
+
BIAFAFFH?@@=HGD@DBG?IFGEBHAA*DDAEGEBGAIDHCFCBDIABEIB@D@?D@F@IAIIGGHH?8@FFAEEDB?HICEB@?AACEHAFBIEG4FB
@>chr21:9543014-9543154-3
ACCACTATGTCAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGCTATCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCAGT
+
EHAEFHDEGBGEAIDE@AGBGC@BBFEGDACDGIHHIBCFHFHCEF@BHFE;CFE?FHC@@BBDHBBGB@ICGAFEDEDHIHCHCBHF?ADBCIC?D@DH
@>chr21:9543014-9543154-4
ACCACTATGTCAGCCCCTGATAGCACCGAACTCNCCCCCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCAGT
+
G?GHCBF?DAEAAFHC?@DBGDGA@BHGFDCEG#DG?$DHHBEACB@HFDE?BDAFBCEIC?EADEEGDEGHEH@HGDA@FG?DBH?CFGB?EBEHAAF?
@>chr21:9543014-9543154-5
ACCACTATGTCAGCCCCTGATAGCCCCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCAGT
+
HE@HD?IDHCG?HA??EEIFFCHA6@B@?DGFCFGBCIIBEB@A?EHBGFGCD@AH?D@EADIEHFABAAA?F?BB@IIIA$DBCBEECIAAABEBGCHG
@>chr21:9543014-9543154-0
CTCATACCACGCTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTATACGCTACTCGTGGCATTGGGGGACGAAGGTGGGGGGCGCTATTG
+
AAAHHHAB@FGCIEEBDAF@DDHGDGCBCFCCEGBFCF?BG?AEC?HBD@DGIACFIE@CB?HA5CCG@EDI?@DIE@AHAI?F?@E?A@EBFBIFFEGG
@>chr21:9543014-9543154-1
CTCATACCACGCTGCAATGCCCATGGAGGAGCACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGAAGGTGGGGGGCGCTATTG
+
EBHHEBE?EEBAECAAEHIE@)IEFIF@HF?!GH@EDABAB@@FDE@DD@CDD@CBAFABF@C?CDGECE@@E@ECAG?AI?G?GICB?HGB?BGHIE@?
@>chr21:9543014-9543154-2
CTCATACCACGCTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGAAGGTGGGGGGCGCTATTG
+
?@IHGDEE@BIHF??IGEEA?FIHGBC@?CDAFEACFCAHCG@C@AF@AE@BFBEE@IAFGADICCBCIIFBDFIADIAHAICF@E@DHF@GDDHG?BDC
@>chr21:9543014-9543154-3
CTCATACCACGCAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCCCAATAGCGCCACCCACCTTCGTCCCCCAATGCCACCAG
+
F?AGC@BCEDD?DE?EC?CE?ECAH@GAEE?FHBGFHF@DHDBFFDIHHGEDHDAF@C?DE7CHBIHEAHGD/@GEIFGHGFEBFEAABCBCAAI@EEID
@>chr21:9543014-9543154-4
CTCATACCACGCAGCCCCTGATTGCACCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTTCGTCCCCCAATGCCACCAG
+
@CFBHHHDE?@AGDFEE@H?AC,DEDHIGDFCC?HCA@@EHDCGEDHDE@GAGCDBIGHAFG@?FDFAEFF@HFEI?AIFA@HBBAB?BIBB@B?DDIA?
@>chr21:9543014-9543154-5
CTCATACCACGCAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTTCGTCCCCCAATGCCACCAG
+
AIFDBBEEDFDEDIEBCDBAFDHD?FB@?IIBGCEA?F?IFIFBFEII?I@H@@D@CABHADAEGGAACDI?@FBAEB?AAAHHHF@EFHBGDDDE@HHG
@>chr21:9543014-9543154-0
GAAGGTCCTCTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGAAGGTGGGGGGCGCTATTGAG
+
BBGEDBDIHFCDEHBDHFHFDFDHHGECABFBD?AEBICGDG?CHGBD@?I@@FIHHAA@CGAC@IGC?GEIGHA@DFFF@CHDEHFDH@FCABEIE??C
@>chr21:9543014-9543154-1
GAAGGTCCTCTGCAATGCCCATGGAGGAGTACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGAAGGTGGGGGGCGCTACTGAG
+
A@DHFI?ABA@I?AHH?GHC@GAHFFH@G'EG?GIDIBCG?GHH?B/FD?FE@DEH@GHHAEHHDF?AAAEHABHADDD?AEAGHIGC?@BEEID,DEDD
@>chr21:9543014-9543154-2
GAAGGTCCTCTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTTTACGCTACTGGTGGCATTGGGGGACGAAGGTGGGGGGCGCTATTGAG
+
CIAE@DF@@HDGACCDI?F?DAIHAHH<?CFF@EF?DHDB?@DA@IAECFIG3BCCI@H?@EBIEBBACF@?HCDGIE$ABFF?EC?EABEEC+C?CEH?
@>chr21:9543014-9543154-3
GAAGGTCCTCAGCCCCTGATAGCACCGAACTCGCCCTCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTTCGTCCCCCAATGCCACCAGTA
+
AIDC?EAB@FA@?GIBD?G?AFH?CI??BC@H?BFG/BIFGH?CFGHCFD@IF@@CAG?GG@FHC@CABEFACHBBHACBI@B@AABI?ADI@?GFAGEH
@>chr21:9543014-9543154-4
GAAGGTCCTCAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATGGCGCCCCCCACCTTCGTCCCCCAATGCCACCAGTA
+
HCGA@BIDCAHAB@CIEAIBDFHBCB@GIGCEHBBDIF@DC@ICIBII@IHCBEHAFABGFIIC%?FDHFC?@F@IIFIIDHBFAE@C?EDEBGIG@GBC
@>chr21:9543014-9543154-5
GAAGGTCCTCAGCCCCTGATAGCACCGNACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTTCGTCCCCCAATGCCACCAGTA
+
CHD@HEHCDFIGEFF@ADABDGA"DEG0@II?ADCDACCC?AB@@DGF?FI@FAE?IAGBE@C@IHAFFFGHCHCC@@DA?HIFEFIC?BBCFBCC?DHB
@>chr21:9543014-9543154-0
GCGGCGTACTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGGAGGTGGGGGGCGCTATTGAGG
+
FCI@IIGHCCAIGEEDBAEG?CGDBGDGG@I@@BAGBFBGACBID?FCHEHGCACDG@FA@@G?H?GEDGBH@FFDACEHB?HGDBDBDHDDGHIEEAC@
@>chr21:9543014-9543154-1
GCGGCGTACTGCAACGCCCATGGAGGAGGACCGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGCGGACGGAGGTGGGGGGCGCTATTGAGG
+
HFGAGA@AII?C@E)BAHBC?@DDAC@IDE@$I?IHDGA@FACEEIDAHEDHABBIEG?HAEE?EGDGH@I@2EGEGHF?@IDIAI?BE@??@GID@E@C
@>chr21:9543014-9543154-2
GCGGCGTACTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGGAGGTGGGGGGCGCTATTGAGG
+
GCGDFDD?HIBFGDCDGGBDEEGHGGCCH@?E?HIA@GAEED??GGGCA@?CE@DBBFEGB@G@BBBGECB?EBFGAC?A?BHGACGCCF?CH?DGHFIF
@>chr21:9543014-9543154-3
GCGGCGTACAGCCCCTGATAGCACCGAACTCGCCCGCCCACCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCAGTAG
+
HDCIGFHGFEGEEAE?E@EGDC?CGCHIAFAIFCBB@?E7?DHHIHC?CAIHGHCEAIDDBCD@E?@DIGHFEF?AGAF@IF?EG?DED?EDCBGFGBF?
@>chr21:9543014-9543154-4
GCGGCGTACAGCACCTGATAGCACCGAAATCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGACACCAGTAG
+
?EGI?BA?FHGF(A?HHAHBGGIIICC@-A?CAGE@@EHFC@CEIDFEAICBICB@BHEFAEBIHCHDCI@@DGFBHCFDC@AGBFHCG@"BBFBA@DAH
@>chr21:9543014-9543154-5
GCGGCGTACAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGATAGCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCAGTAG
+
BCB@DDFEBCHBGIHEIICIHB?HA?F@BDGHFDIADH?EBICFHF;G@DA@CF@ICG?EHC@B@EHFFHHFBAHGCGIIGA@BA?ABDIGGDF@BA?AD
@>chr21:9543014-9543154-0
TCAGACGGTAATCTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTANCGGGTATACGCTACTGGTGGCATTGGGGGACGGAGGTGGGGNGCGCTATT
+
D@?BFBBDHEBCGCGD?E@IC?DBII?B@DGEEFAHEBIICDABD@EGH$HD?FI@GFCI?HAA@FECFB?IHCBEF@@AFEEIIEGCF?I5DGDI@GA?
@>chr21:9543014-9543154-1
TCAGACGGTAATCTGCAATGCCCATGGAGGAGGACAGGTTAGNGTACTATCGGGTATACGCTACTGGTGGCATAGGGGGATGGAGGTGGGGGGCGCTATT
+
DAD@?DHEA@FIGACGBFAIBDBBD?@GI@GIEDDAD@??AG"?)@EIIHFBEF?CGAHGHF@DHFE?AB?HC;DD?HGG0CFH@BIBHIH@A@GGGEE?
@>chr21:9543014-9543154-2
TCACACGGTAATCTGCAATGCCCATGGAGGAGGACAGGTTAGGGCACTATCGGGTATACGCTACTGGTGGCATTGGGGGACGGTGGTGGGGGGCGCTATT
+
@FB$CDGIHED@B@AAACIACIGBIGGCEBEDA@FCBHCD?IGGC?@E@HE3FHDGICFHDFDHEC@EHEFECCBEE@GFIAD9B@G@AG?HBAC@@?FA
@>chr21:9543014-9543154-3
ACAGACCGTAATCAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCTATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCA
+
6FA?FA5EEBDBCCF@CFFAIBEHHGD@CDFFEEGGAC@GFEFFBIG?DBEGFBFCIIBHAAGF8?IDCDD?@H@GBBEEA?HDB@IFACDGFBF?A?HA
@>chr21:9543014-9543154-4
TCAGACGGTAATCAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCA
+
@BGEACE?EEECF@GIFAB?AHFFIIBGBAGCIIEG@?BDEHD@?HEF@DIIC@6ABH?EH@AEDC@HGHAA?FIDBHABEGDAD?AHEAHHABDAHEDF
@>chr21:9543014-9543154-5
TCAGACGGTAATCAGCCCCTGATAGCACCGAACTCGCCCGCCCTCCACGGCTAGCCCTGCCCTCAATAGCGCCCCCCACCTCCGTCCCCCAATGCCACCA
+
HI?G?FIFEAHHGCBEF?FACABBGAD?FEAEHDHIACD@AGHDE?D@DFHDID@I@I??F@CHE????H?FHAED?B?@?ECCHIAHFGCAFF?C?FAI
@>chr21:9543151-9543274-0
ACCACTATGTCTGCACTGCTGGCGGCGGTCAACANAGTTGGCATCCAAGGAAGGAGTGGTTCTCCTCTGCCTNACTCCACACTCCAGAGGGCGACCCACT
+
AEHF??I@GGDFDFHDH@??IHCDHCC@CDCAFI.?E?AE@HEIFI?FHG?AE-FDBHGHB?D@?@DH9AFG8@CEDBGHEFCBIIG?BD@GC?HDHGBC
@>chr21:9543151-9543274-1
ACCACTNTGTCTGCACTGCTGGCGGCGNTCAACAGAGTTGGCATCCAAGGAAGGAGTGGTTATCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCATT
+
?ED?C?*H?GBCBF?HF?AFCIHEHIB3GEIIHDFEIG'GG@I@B@ADAG?DCGAI??FDG,G@@G?@@GEBD?CD?CDBFAHHICEHCBDDAD?HD?5C
@>chr21:9543151-9543274-2
ACCACTATGTCTGCACTGCTGTTGGCGGTCAACAGAGTTGGCATCCAAGGAAGGAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCNACT
+
EBIFG@?A@EEAG@FCFFDDH<.IAB?EFCC?AAD?B@G@G@I@?DFHEIEDBBDCIGADADDFCEEAED@CBEAEAF?IED@F?BBHEEAAGBGI+DIB
@>chr21:9543151-9543274-3
ACCACTATGTCTGCGTGCCCTGCCACACTCCATTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTCCTTCCTTGGA
+
AGCEDBDIAIDCHBGEIAD@D?AFFIH?GHHA0HI?EGBAG@EFHBFA@BBGFCHAH@D@IFH?HGI@H??FGGFH@HHCHHCDAFA?BF?FHFAD@"FG
@>chr21:9543151-9543274-4
ACCACTATGTCTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGNTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTCCTTCCTTGGA
+
A?B(AFHCF@HCCEICBBIABHF?I?FCEEGIGCDCGACBEBDGFGBI;FGHIACDG?HEADH?EGF@FFGHHFEDBEHHIDCDDHFB@EECBBGD?HBB
@>chr21:9543151-9543274-5
ACCACTATGTCNGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTCCTTCCNTGGA
+
CDF@?IFAADD!DHEECADGCGACH,EDEAGHIDEDHAIG@CDDCCHCBICGED?AF@ICDE@FEFE?EIGFHGGGHBBCGGDCI?EBCEF@BAC>BGIH
@>chr21:9543151-9543274-0
CTCATACCACGATGCACTGCTGGCGGCGGTCATCAGAGTTGGCATCCAAGGAAGAAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCAC
+
AEBBECIIBEE>GIGHBFCBBIDBBGGFA?F@,GEECEEADDCHIGD?BHI@G@ACEG?FEAAIDFIHHA?E@?E@AEHDDGB@AEIC?FI????FGGHI
@>chr21:9543151-9543274-1
CTCATACCACGCTGCACTGCTGGCGGCGGTCAACAGAGTTGGCATCCAAAGAAGAAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCAC
+
FCIADIGEI@FBBC@ADAD@B?BCHFF@HEC@IH@AGEDGDDCFI@IHH4CBABCC?HGCF@@C?<AIHAHEGDB@ECAA?@AABEAGFGDDEDHHEDBE
@>chr21:9543151-9543274-2
ATCATACCACGCTGCACTGCTGGCGGCGGTCAACAGAGTTTGCATCCAAGGAAGAAGTGGTTCTCCTCTCCTTGACTCCACACTCCAGAGGGCGACCCAC
+
#EBCCGF?BEFADFCGHFADFFFGI?@FAFDCG?HFGBFB4AI@@DIFCDEB@@BCBGCGA@AEGB?GFCA<?AFGIBCDCCEIGGA@?GEHFB?DIICE
@>chr21:9543151-9543274-3
CTCATACCACGCTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTTCTTCCTTGG
+
DIBHF?FAFCB@?GEBIDFAHCIIDB@GF?FHBEIBCB@BGDCH@DHBHHHBBE@F??EGFG@DDACIGEHAFDFFG@BI?FDBE@?EBCHF?G?GC@C@
@>chr21:9543151-9543274-4
CTCATACCACGTTGCGTGCNCTGCCACAGTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGNGGAGAACCACTTCTTCCTTGG
+
?HIHADICGFA.E?DEFB@(GBEAEIAB&IEB?CGCF?G??DHAI?ECHAF?I@ACH?@FFDAIGBAI?DIECED?@F(IBAHIB?H?AF@BCACHABFD
@>chr21:9543151-9543274-5
CTCATACCACGCTGCGTGCCATGCCACACTCCATTATGACCAAGAGTGGGTCGCCCTCTGGAGTCTAGAGTCAGGGAGAGGAGAACCACTTCTTCCTTGG
+
?@EFGA?BA?EGACB@FBCD*?HGEBHFAGDFC:BGIH@FFDEA@CBBGH@GFEAB@ICC?FIG:I>?FCF*AHHHHGFBHCDHGA@@AB?H?EGHHCAH
@>chr21:9543151-9543274-0
GAANGTCCTCTGCACTGCTGGCGGCGGTCAACAGAGTTGGCATCCAAGGAAGGAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCACTC
+
@CE:BHGAA?@EE?BDEIE@CIEDHGFGF?FEECIEHFBDHCFH@@HEA?D@H?ED?DI@ABHIA@BDGFEEFDBCDAGFBEB?G@A?E?GDBFG@DA?B
@>chr21:9543151-9543274-1
GAAGGTCCTCTGCACTGCTGGCGGCGGTCAACANAGTTGGCATCCAAGGAAGGAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCACTC
+
F?HFB?IC?B@DICFBB@CBB@EF?I@BGFBIC6AB?I?B@EEDE@HCCAH?EFA??DIFCAC?CG@GDDABI@BAEDB@FI@EEDCG@HDGAA@C?DBB
@>chr21:9543151-9543274-2
GAAGGTCCTCTGCACTGCTGGCGGCGGTCANCAGAGTTGGCATCCNAGGAAGGAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCACTC
+
B?AHFGI@?HFAHEBIBEGF?CHIADBDFG"?F@FFFF??ECDCH5?HCCCBF???E@AI@EHBA?E@??A@IEGBHIFAGGDFHGCCH@BFBDF??BEA
@>chr21:9543151-9543274-3
GAAGGTCCTCTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGACAGGAGAACCACTCCTTCCTTGGAT
+
DABABDFAHB?H@FDA?AACFI?DHHEA@BI@BGAIHDFDCIBAHIF?D?BFGDEEE?IF?GI@G?GGDEBIBEE3?AGEIGDGA@GBFFEGIBICAABA
@>chr21:9543151-9543274-4
GAAGTTCCTCTGCGTGCCCTGCCACACTCCAGTANGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAATCAGGGAGAGGAGAACCACTCCTTCCTTGGAT
+
G@HF'HII@DH?D@?DI?FIHHHIHIHIEIDA?H8IGCGBHIB?GHA@BFCBCF@?II@IDBDCBDB;?GBB@BCIGA??GEB?B?IDFFCB@AE@EIAD
@>chr21:9543151-9543274-5
GAAGGTCCTCTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAAGGAGAGGAGAACCACTCCTTCCTTGGAT
+
III?D@?HIAFFF@DDFDACHG)AB/HEHHEHI?@DIHI?@BFEEAHCFG?ABIGCA?@AFBE?BFDGFFI%BDBCE?BIEC?F?@FF??DBECHCHEAB
@>chr21:9543151-9543274-0
GCGGCGTACTGCACTGCTGGCGGCGGTCAACAGAGTTGGCATCCAAGGAAGAAGTGGTTCTCCTCTCCCTGACTCCACACTCCAAAGGGCGACCCACTCT
+
CG@AGBIFIIC@BBC?DGFIIEII??EACGCF?GBDF@@@EIGDDB?FCFDIHECFFBAIHGEFGF?DB?G8@F@B@AAGCC#H,D@AH?FIDG??H@@H
@>chr21:9543151-9543274-1
GCGGCGTACTGCACTGCTGGCGGCGGTCAACAGAGTTGGCATCCAAGGAAGAAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCACTCT
+
GB?A)@HGC?BB@ADGHCAA??CIDAH?HIHCHGDG@@HD!@FFIEAAE?DDEIFCDIFDGGEAHAADF@@F@BHEDC?DIBCDI??HDF@FIFA@HHBF
@>chr21:9543151-9543274-2
GCGGCGTACTGCACTGCTGGCGGCGGTCAACAGAGTTGGCATCCAAGGAAGAAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGACGACCGACTCT
+
EF@H?C@FC@FFICEFHHH?CIIHDGADDDBEA@DIAAEAE?HAAAEIDEDHCF?@@ICFE@IH@@C?HAIGGCCCEDCAHBHBFFAH<C@ACB:BA@DI
@>chr21:9543151-9543274-3
GCGGCATACTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGGCCCCCTCTGGAGTGTGGAGTCAGGGGGAGGAGAACCACTTCTTCCTTGGATG
+
@ECAG,E?CDCI@DDG@?BEHIE@GA?@DC@@B@DDEE?DF?@@AHE5@7HBEHGGIEADGDIIABGACFBDA8G@CBD@BEIGCHIHHABACFDDCBAG
@>chr21:9543151-9543274-4
GCGGCGTAGTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTTCTTCCTTGGATG
+
CHC??AFA:GDIAFAC@FGECGFBDFFHD@GE@CIDDHA??DA@FCI?EA?AFDE?IAFEFBF?BDHD@GEDFDIGBC?DDACB?EBBHEGEE?BGGAHG
@>chr21:9543151-9543274-5
GCGGCGTACTGCGTGCCCTGCCACACTCCAGTATGACCAAGCGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTTCTTCCTTTGATG
+
ACA?HCHIBHH?HBDFEFFCEH@E?DHE@C?IBEIGG?FGA0@A@CDIHDBEIHC@@EA@GHIC?CI!DI@@ECAAEGAEHBGFAG@FIBF@IDB"EI@F
@>chr21:9543151-9543274-0
TCAGACGGTAATCTGCACTGCTGGCGGCGGTCAACAGAGTTGCCATCCAAGGAAGGAGTGGTTCACCTCTCCCTGACTCCACACTCCAGAGGGCGACCCA
+
CBIADGHI@ABFIHCADF@HAD?CGHGIAHE@EGDDHHFBAI8AFGCFFC9IHEA?A@I??BF@8B?EDDA@@HDDDC@FBIFGCCFADDA?FEIDF?BA
@>chr21:9543151-9543274-1
TCAGACGGTAATCTGCACTGCTGNCGGCGGTCAACAGAGTTGGCATCCAAGGAAGTAGTGGTTCTCCTCTCCCTGCCTCCACACTCCAGAGGGCGACCCA
+
BA@?GBAEHFCCGF@DFIGBH?@%CIEBIFAEAGFCIADAHDB?B?G@IE@GBAH7AC@?C@EFADEEGI?IH?D7EIC@?@AEA?@?E@HBCD@I@EEI
@>chr21:9543151-9543274-2
TCAGACGGTAATCTGCACTGCTGGCGGCGGTCAACAGAGTTGGCATCCAAGGAAGGAGTGGTTCTCCTCTCCCTGACTCCACACTCCAGAGGGCGACCCA
+
I@?F@AI?HIAAAHECFGAI@CIFHBG?GGHBG?B@HA?EIACCDB@@GHCAEHD@A@?DHGIEDGF?HE6DGEHE@HEC@?C?FFEGH?ACCB@AI@DI
@>chr21:9543151-9543274-3
TCAGACGGTAATCTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTCCTTCCTTG
+
FAHFBEFI?FFIFEEE?DAEE?EHGA@DC@DIH@CFBAI@HH@CGEGEBCECECIGHF+AE?CBAD@D@?EABF@FAEEHIGI?CDA@H@AGBGIACGCA
@>chr21:9543151-9543274-4
TCAGACGGTAATCTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGAGAGGAGAACCACTCCTTCCTTG
+
IE?IFABEBACAHIII@CFE?E?BCHI@?HBG?HFDAADGDDACCHBBAFBH@G?HEGE@ADDDHBAG@IIDDDEHHCGFBICIIGHCG?DG@BCID??C
@>chr21:9543151-9543274-5
TCAGACGGTAATCTGCGTGCCCTGCCACACTCCAGTATGACCAAGAGTGGGTCGCCCTCTGGAGTGTGGAGTCAGGGTGAGGAGAACCACTCCTTCCTTG
+
ADCBIII?AFC@HH@@IICIIFDAHBA@CFAGFDBG@GCBB@D?@FDIDB?BGGDIDBHHBAF@@DI@DCEH?BH?I#BFD@A@@FG?@D@HAIGAHADD
@>chr21:9543271-9543364-0
ACCACTATGTCAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCTCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGAGG
+
IHIFBDBIHH@IFB@DFEGFGA@CCIGHEFDFD@CCDCHDBDGCBHGECHBCGAFC@AAEHBAD@CGGIBE@HF?DABEB?AHAGAHCCEIDAAGAGDAI
@>chr21:9543271-9543364-1
ACCACTATGTCAGCGTTTGCATGGGAATCCTGAGCAAGGCAGAGCCCCCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGAGG
+
?HBEDFHAACB?EG???D?EGIFIAD?AI@B1BIFA%HIDI@B?AC@@?IDG??ABAAIBHB?H@ADHIGC?EHA@CDE@?CAGADGC?DIBFBH@G@DI
@>chr21:9543271-9543364-2
ACCACTATGTCAGCGTCTGCATGGGAATCCTGAGCATGGCAGAGCCCCCACACCCACCGTGGTTCCTGGGNCTGTGCACTCTGGGTCTGTGCCTCAGAGG
+
@GE??EBGF@??DA@H:@@FBAIFBC?BBBD@BDHGB@CFBHHGABA?FH?BAHBBCB@GIGDHAIG?I@3GBFDBAHAHB?HA@DCGE@AAEFIGHIIF
@>chr21:9543271-9543364-3
ACCACTATGTCAGCCTCTGAGGCACAGCCCCAGAGTGCACAGGCCCAGGAACAACGGTGGNTGAGGGGGCTCTNCCATGCTCAGGATTCCCATGCAAACG
+
BBHFGHHCF?EEGI?EIGADAFGHEHI*EA??AGB@FAHAA?BCDFHFAEGH!AE?IBBG/@D4B@G?HGEEE3DC?ADI@BHCC?IDABFHADADGHI?
@>chr21:9543271-9543364-4
ACCACTATGTCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTAAGGGCTCTGCCATGCTCAGGATTCCCATGCAAACG
+
?EEDECF@GCCF@DDHFDIF@GF?@@CD@IEFFFEGHAF?FBFHBGEGCE?FBGC?FFAGGAB?,AEIA@FDG?IDAH?GF@CDG@B?@??GCBEEFHAD
@>chr21:9543271-9543364-5
ACCACTATGTCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAACG
+
CAEBCDBHIBDE?GIGFDIDBFCGFI@G'?BBHBFBHF??GHFGI@@C?@GC?@E?EIEFDEADIG@AA@CIIFD@D@?CAEGIHF?HEBAG@AG?IDFC
@>chr21:9543271-9543364-0
CTCATACCACGCAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCTCACACCCACCGTGGTTCCTGGGCCTGTGCACTCNGGGTCTGTGCCTCAGAG
+
?A?DBGHH@FDFIIF@@DAIFEC@BCCABC@DAEIGEAGHG@F@GDAGIDI?BBGD@BGE@DE@GFC@HGCE@HGIG?HGA@5BEDCEE??DDDDFBDAB
@>chr21:9543271-9543364-1
CTCATACCACGCAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCCCACACCCACCGTGGTTCCTCGGCCTGTGGACTCTGGGTCTGTGCCTCAGAG
+
??CDAAHBEAGD?DCBB@GFD?DDIH?FE@GH?DBG@?BBIAACHE?CCHFGH@@HF@DIB?I??CBC:BFA@EFB@<?IDCFEHFHE?@DAIEII?F@A
@>chr21:9543271-9543364-2
CTCATACCACGCAGCGTTTGCTTGGGAATCCTGAGCATGGCAGAGCCCCCACACCCACCGTGGTTCCTCGGCCTGTGCACTCTGGGTCTCTGCCTCAGAG
+
FEGEHAEIGIEFICFEDDBB?9EAIDBIG@IGHG@BC?D@FBDBEDDFHBAHICBC@EEE?HIFG@D?)AC?GH@DACFB@@HGADEFC>E??FGD?<@?
@>chr21:9543271-9543364-3
CTCATACCACGCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGGGGGCTCTGCCATGCTCAGGATTCCCATGCAAAC
+
IAA@DI@?BHD@BC?GCHDIACE?AE?@IDH?AHAAHGHBAADFII?IGH@EAGBHGBADII?IBEA@GAAEA?HFAGA?GCBDDCH?FAEBEA@EDH@@
@>chr21:9543271-9543364-4
CTCATACCACGCAGCCTCTGAGGCACAGACCCAGAGTGCACANGCCCAGGAACCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAAC
+
@@G?@GDBEA?@GBEHBHDGD?ADII@BG@DHDGE?DHCDE?8BIHCBCH@GBGDIEC?FGCGI?AIBECCF@DDI@A?EICIEBEDCGGGAIGGE@HHC
@>chr21:9543271-9543364-5
CTCATACCACGCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAAC
+
GHIA??BFAEFFBCCIH?BIBA??FEEAI@E@ECCCHCEGIEECE@G?GDDG?FDEGAHGEH@E@HBCBAABGC@DICHECABD?CAI@D@ICAAAIGDA
@>chr21:9543271-9543364-0
GAAGGTCCTCAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCTCACACCCACCGTGGTTCCTGGGTCTGTGCACTCTGGGTCTGTGCCTCAGANGC
+
BBH@D?BGDCCHDFAH@BH@G@DGHDEHI?HIECBGHHE@AIG@AFDHDEAIBHHF@C?B?F@BEDG@E"HAEE??HEAAAGC?DB@I@DHH?GC@?"CH
@>chr21:9543271-9543364-1
GAAGGTCCTCAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCCCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGAGGC
+
DBGHIFIDEEDHICGHGI@IFEFF?HIC?BECFFBCACE?@G@GCB?@GAAHFEI@@D?IHF?AAEEGHIEEDA@@FF?CBEEBF@DFIFDAGCAAAFBH
@>chr21:9543271-9543364-2
GAAGATCCTCAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCCCACACCCACCGTGGTTCCTGGGCCTGTGCAATCTGGGTCTGTGCCTCAGAGGC
+
%AGC-?FIB?HAB?HCBIBCIADGEDFI@CACDIFIGBIHBG@AD?E;EAH@EHC@@GFCAAFBDCDF?H@IHDAFG0@IBI@ADFDFGF@IHBIIH??@
@>chr21:9543271-9543364-3
GAAGGTCCTCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGGGGGCTCTGCCGTGCTCAGGATTCCCATGCAAACGC
+
CFGA@@CBEAAHAGHAD?BEDHCGFGBGAHEA@DAIEAGAH@DFGFBIEH?HG@FBI@CEDCG?FDA??BI??G?8A@BE@FDEEFD4FGFCECDF@GF?
@>chr21:9543271-9543364-4
GAAGGTCCTCNGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGNATTCCCATGCAAACGC
+
DEGEGB??B?&HBDCAI?@@G?EIIHIADB??BB@CEGDACC?I@@3FCIABE?GB?GCAHFECGEADF@I@EDEBEEFBBDF=CE?@?EGAAEDBHEBH
@>chr21:9543271-9543364-5
GAAGGTCCTCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGTGTGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAACGC
+
B@CHFE@GEI@FEIFE?A?DGDDGFEFICEDBEAHBFA@D@?BH@GG@BHDDEHECC@,FDCDCEDGFED@HHICFCHAF?EAEFIG?@?EDADAIBGH@
@>chr21:9543271-9543364-0
GCGGCGTACAGCGTTTGCATGNGAATCCTGAGCATGGCAGAGCCCTCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGAGGCG
+
FFD?GEABCFFA?EEBDGCHA+HFIC?@ACGFIHC@@CIIA?FAHAC)@IIHDIAAEDA@E@I+?IDEADGIEHBBHAEGFC?EC@@A@?EGFA@IF@E-
@>chr21:9543271-9543364-1
GCGGCGTACAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCCCACACCCCCCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGAGGCT
+
GHB?GAEAIHA?I?GCHBHH@ACG?DFD?FHCFHGAE@FA@FIGHBFH?DH??1HBCFFIB@EDFAIBHIFEGCB@HAG?D?EDF@H?HDGCH@GFDD?G
@>chr21:9543271-9543364-2
GCGGCGTACAGCGTTTGCATGGGAATCCTGAGCATGGCAGAGCCCCCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGAGGCT
+
AA?C?DI?E@A?HEECC?HBCIF@AF@GDCBDBBHDDG?CGBF??CBAFEICF@CAGDBI?AH@HAFDIB?H?AIABHDE?A@@AGD@CD?A?DAGAEDG
@>chr21:9543271-9543364-3
GCGGCGTACAGNCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGGGGGCTCTGCCATGCTCAGGATTCCCATGCAAANGCT
+
CCDH@HABGGG2EHA@HII?FIFEI?B?CBCGE@FBCEI@FCEDCEAF@E@EB?HD@HC?B@@I?G?BHFIFB?DIH@B?ABIFAFACGF@@F@AB%BF?
@>chr21:9543271-9543364-4
GCGGCGTCCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCGAGGAACCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAACGCT
+
??ACHFI<CIA@E?E?GBICA?BA?IFFCHICIH??DHAAHAG3IAI@ADIBCFCGFGIFBD@AIEADDAHDED@EDACHCCIE@CBDBHIDAHCHIH@H
@>chr21:9543271-9543364-5
GCGGCNTAGAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGCGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAACGCT
+
@EFBI,DB&IED@HDHHA@@FC?EC?AFIICHFFHCADECAFGF@C??GA?EADEEGFG:DGACCEGBCCGHHHFCCHCIIC@BF?D?H?BHDGHACIA@
@>chr21:9543271-9543364-0
TCAGACGGTAATCAGCGTTTGCATGGGAATCCTGAGCCTGGCAGAGCCCTCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGA
+
IFEBA?GDFDI@EFAI@GFF?B?IECDFFHDGGCAGA!DA@DDFBFCCGI?ECH?FAFD@@?CHG@H@AIDADFBGD@GHIACEAE@?CI@HAHG@FAED
@>chr21:9543271-9543364-1
TCAGACGGTAATAAGCGTTTGCATGGGAATCCTGAGCACGGCAGAGCCCTCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGA
+
?FBHECFCIEF?3IICCEHGI@BIIE?ABICH@AADFC*?A@@HB?CAIFDGFE?EHCBC@BGBA@BG@ED@DBCCE??HDFD?CBCDFCFBEEC8FACI
@>chr21:9543271-9543364-2
TCAGACGGTAATCAGCGNTTGCATGGGAATCCTGAGCATGGCAGAGCCCTCACACCCACCGTGGTTCCTGGGCCTGTGCACTCTGGGTCTGTGCCTCAGA
+
AAEEFE?CGHI?CG@F@*D.AGDBFB@ABIGIDGABBHHEI?BEF@I@B@GADBIH@H@D@BFGCF?CIAFF@CDHFAIHBD-AGE@DFD@CD@IFAAGA
@>chr21:9543271-9543364-3
TCAGACGGTAATCAGCCTCTGCGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGGCTTCCCATGCAAA
+
EIIEGCGD@DAACGICIAD@E+@B?@A@BE@AE?D@GIHF?CADGBC@GBB??BE?A?GCBBECHIEHBCE?EIH@F?FHD?G?AAA3IIBBCBABCIAF
@>chr21:9543271-9543364-4
TCAGACGGTAATCAGCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAACCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAA
+
CDFABD@IA?CHBCGHF??@BAAHI??@H?GEGGFIBICFBGEGDHFDBBED?@IEGEF@?IDH@C??BHGC?AFB?AFIEDBBIDFGC?EAHEBH@?@C
@>chr21:9543271-9543364-5
TCAGACGGTAATCATCCTCTGAGGCACAGACCCAGAGTGCACAGGCCCAGGAANCACGGTGGGTGTGAGGGCTCTGCCATGCTCAGGATTCCCATGCAAA
+
IEH?BHGHCAACCG>IAHIHICHGABCFBEFCE?EECBECGFBCBB?@GBHDG&IFEGHIHIHI?FFBHAFHC?AIDG@?F@FG@FHFEAIHEDCBGCBA
@>chr21:9543361-9543498-0
ACCACTATGTCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCACCTGGGTGTGGAGGGCT
+
G?CEIDFHI?F?GA?FHIF@BIFI@FHHFAACFEHEBAEE?DCFHDHGA@IBGAIB?EBBED@CBAGCBGDGIH@CFFEFADDBDC@ED?BA?IBF@EEE
@>chr21:9543361-9543498-1
ACCACTATGTCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCACCTGGGTGTGGAGGGCT
+
?B@EBACHAFCCAEIGA@?FDI?FBE@FDIDFC@GECIC?BC?AACBCBGECAB@D@?BDFGHFF@GGCBFH?I?EHBIIGAEG??CCAGEH@@AACB?H
@>chr21:9543361-9543498-2
ACCACTATGTCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTCTGTGTGGAGGCGTCCGGAACAGGAATTGGCACCTGGGTGTAGAGGGCT
+
GBIIII@?DEGAH?C?DIAF@?FHIACCBCFHDI?IHACIHCCDFBGF?DB;?C,FI?E@FGEHIDE@@DEAE?ECCI@AHCHIBGC@GACG#CE?@BBE
@>chr21:9543361-9543498-3
ACCACTATGTCTGCACTCCTCGGGGAACAGGAGAAGCAGAAAAATTCAGACCCAACCAGCCCTCCACACCCAGGTGCCAATTCCTGTTCCGGACGCCTCC
+
@DF'IIFAFDHA@A@GDCIBECCGA?G@BEBDDDG@DFHD??HBE?@B#DED?BBDFAE?E?CDDDI?BCHB?BBBGFFFDEEE?DDDEDC@CEB?@EBD
@>chr21:9543361-9543498-4
ACCACTATGTCTGCACTCCTCGGGGAACAGGAGAAGCAGACAAATTCAGACCCAACCAGCCCTCCACACCCAGGTGCCAATTCCTGTTCCGGACGCCTCC
+
DIHFH@HDG?GGDGCB?GBGBI@GHAEBDAC?F@CICCAB/@DICDFIIFGEACCECIGAB@CEDGB@@CGDBDBGC??AHH?IH@ICBBGCHBG@AH@@
@>chr21:9543361-9543498-5
ACCACTATGTCTGCACTCCTCGGGGAACAGGAGAAGCAGTAAAATTCAGACCCAACCAGCCCTTCACACCCAGGTCCCAATTCCTGTTCCGGACGCCTCC
+
BEEDEG?F@AAGEIDAA@HFB??@GAEFIGBDCDH@FFF.I?ECICD@?CECEGAID@FIBHF;AEGBDHGCCFD6D?ADCDACEF?FIGBFFDC@GDEA
@>chr21:9543361-9543498-0
CTCATACCACGCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCATNTGGGTGTGGAGGGC
+
EAFGHBA??CC@ID@E??AB@EAE@G@ECDG@GIAEGEDDF@@?D?A@?IGFFIGADECICHDDAAEFGGAD?G@A?DIF@ACG@6CFEIDH?AFBBFGB
@>chr21:9543361-9543498-1
CTCATACCACGCTGTCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCATCTGGGTGTGGAGGGC
+
@?CEGHAH@?@EEA9FEDCEIAEB@EC?HFCAHGI@BD?IIBDIE@IG@HFCHB(@BE?E??I@ECH?@F@FDBAH@AE@D@HBE@EE?HHCBFED?ABF
@>chr21:9543361-9543498-2
CTCATACCACGCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCATCTGGGTGTGGAGGGC
+
@C?@GHFFB1FCFBD?HIHHIFHGA@GI?F?FDF??CCE?EGCCI?DHI?@EBA????@DFDCFI?FDAA?H?BHGIAFI?DCGI+@FBF?FADACE@DD
@>chr21:9543361-9543498-3
CTCATACGACGCTGCACTCCTCGGGGAACAGGAGAAGCAGTAAAATTCAGACCCAACCAGCCCTCCACACCCAGATGCCAATTCCTGTTCCGGACGCCTC
+
IEA@GGB5A?A?EECC@EDGI?DCHDFAF?BAID?CICEC0GB@G?CAE??BFF@GAGBCFDCDGEECFBCGBCAGDB@FIFH@FAHAFIEAAAABGCAE
@>chr21:9543361-9543498-4
CTCATACCACGCTGCACTCCTCGGGGAACANGAGAAGCAGAAAAATTCAGACCCAACCAGCCCTCCACACCCAGATGCCAATTCCTGTTCCGGACGCCTC
+
DBFFBAIHF?DFFDCGGIHGGEB@@BHAFD=HBEBD@BGB?B@CIDGD@G?FEBCE?FA@DFAACB?HBF@BC@?GEAF@HBBIGFCFIA?AGCECAIFB
@>chr21:9543361-9543498-5
CTCATACCACGCTGCACTCCTCGGGGAACAGGAGAAGCAGAAAAATTCAGACCCAACCAGCCCTCCACACCCAGATGCNAAATCCTGTTCCGGACGCCTC
+
IA?CIIG@??ABA@HA?DEAECHBGGGF?DBD@BDFA@BIB?EH@FC?@IG?FA?G@GDDBE?FGFF@EAEBI?EI@D1BI(@I@BDIDCEED@@?GEGA
@>chr21:9543361-9543498-0
GAAGGTCCTCTGCCNGGCACCCCTGGGGACGCCACGGGGGACAGGGCCCTGTGTGTGGAGGCNTCCGGAACAGGAATTGGCATCTGGGTGTGGAGGGCTG
+
C@?CDEAG@,FA?@;CHGBBB@DCBGFGEH1G?CCFH?CHFFAGBI@IE?EGBCICCFABBE.AFII?@=BHFB@CAE@@G@EAEHEFE@BDFE?@DGBA
@>chr21:9543361-9543498-1
GAAGGTCCTCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCACCTGGGTGTGGAGGGCTG
+
GGGGIEBBHCEDGG@ECGI?GBFGE?EIGGGEFH?GHBG?BICDCDDBFEEHG?I@AF@ABIIC?@CICA@DDBH@?EDBEHAGDC@@?IHGFEG?F@CF
@>chr21:9543361-9543498-2
GAAGGTCCTCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCACCTGGGTTTGGAGGGCTG
+
IIEAHG?GDCADIAC?FHCFEB?EFEGGECIFGA?@CC?CAC@@DAECFDAH?I?AAFH?@F?AF??G?BHG?HFFIEBDCGCB?DDBH"DGED@@IEFI
@>chr21:9543361-9543498-3
GAAGGTCCTCTGCACTCCTCGGGGAACAGGAGAAGCAGAAAAATTCAGACCCAACCAGCCCTCCACACCCAGGTGCCAATTCCTGTTCCGGACGCCTCCA
+
@GIHCC@DHCC@CEEFFHGGEEBFHFHE@IEDHIEHI?AAD@ADBHFHDDDBACHD?@GHBCAF?DCBD?B?@IE?EHHIBIFEDBEFDBEIIDDBGDAB
@>chr21:9543361-9543498-4
GAGGGTCCTCTGCACTCCTCGGGGAACAGGAGAAGCAGAAAAATTCAGACCCAACCAGCCCTCCACACCCAGATGCCAATTCCTGTTCCGGACGCCTCCA
+
IH3AG?I?HGB?EHIBGAEDHBCAH@BEIBCD?AA?DHGIE@CDI?GH@GBDBAD?BBCIGBI@BGH?I@GEHIIBI@EC?EI?@EGCFBEA?D@@??H@
@>chr21:9543361-9543498-5
GAAGGTCCTCTGCACTCCTCGGGGAAGAGGAGAAGCAGAAAGATTCAGACCCAACCAGCCCTCCACACCCAGATGCCAATTCCTGTTCCGGACGCCTCCA
+
GDBECAHI@C@DC?EAABGB?@@G@E#DBBCICFIA@GIBC&C@BIGGHCHIFCHGBCDCHA@B8?IACHG?@?@EFBIGHA@GHIEIGBBGHCHADIDB
@>chr21:9543361-9543498-0
GCGGCGTACTGCCAGGCACCCCTGGGGACACCATGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAANTGGCATCTGGGNGTGGAGGGCTGG
+
CBD?@G@?AF@GAIH?@@?A?ECG@EHECEE?H*HHDGF@DFIFGIF@I?CBHFEDD?BCEIHGCEI@GCA@DEC.BFIHIH@ACIA2BH7?G?HCAEE?
@>chr21:9543361-9543498-1
GCGGCGTACTGCCAGGCACCNCTGGGGACACCACGGGGGACAGGGCCCTGTCTGTGGAGGCGTCCGGAATAGGAATTGGCATCTGGGTGTGGAGGGCTGG
+
HFCAA@?H?ACGGE?EFHIA"IHEGF@CBBFIGAGICHCIADDFBIIBB?F+HCFFG?I?EAHGHFHEG6BE@HCIFCIHG@GAHAEH?AACEDEF??CC
@>chr21:9543361-9543498-2
GCGGCGTACTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTNTGTGTGGAGGCGTCCGGAACAGGAATTGGCATCTGGGTGTGGAGGGCTGG
+
@IEGII@G?@HFIDHFE?GFGBCECICF?BBFCCC?AECHAIFI?ACGE9CDECEAIHEBEFHI@@HDH@IACB?IF@HD@BEE?DEHGGGFGBIA?FG?
@>chr21:9543361-9543498-3
GCGGCGTACTGCACTCCTCGGGGAACAGGAGAAGCAGAAAAATTCAGACCCCACCAGCCCTCCACACCCAGATGCCTATTCCTGTGCCGGACGCCTCCAC
+
H?HH@GFFGDAHCGCIHHCF@I?@ICDIIABEFBIEDHHADC??DCB@FHE<AIBDGBB@DBIBFE@E@IDG@@IH6?EFIGICI$DGBHII@HFCICAC
@>chr21:9543361-9543498-4
GCGGCGTACTGCACTCNTCGGGGAACATGAGAAGCAGAAAAATCCAGACCCAACCAGCCCTCCACACCCAGATGCCAATTCCTGTTCCGGACGCCTCCGC
+
IEEHCFAC?GH@ACCH3B?BD@HFFH?>AE?DEEG?I@E?EIG&IH?DBIDA?CDHHBGFBGIGHI?F?C??FIHBGEIAB?I@?GHECDCG?CGCB?3@
@>chr21:9543361-9543498-5
GCGGCGTACTGCACTCCTCGGGGAACAGGAGAAGTAGAAAAATTCAGACCCAACCAGCCCTCCACCCCCAGATGCCAATTCCTGTTCCGGACGCCTCCAC
+
D@FBCDBCH?DDEFBAIAGG@?FAGGADIGAG?B3BACCDCBBB@D?EDEHC@IHHIADD?HBDH-GAHIIBHB@FICCB???CAB?FFI?BH@HHIAAD
@>chr21:9543361-9543498-0
TCATACGGTAATCTGCCAGGCACCCCTGGGGACACCATGGGGGACAGGGCCCTGTGTGTGGAGGCGTCGGGAACAGGAATTAGCATCTGGGTGTGGAGGG
+
CA@(IFEHC@DIADIGHC?AA?E@DFHDCC??DHIEC+?DEAA@D?EICHIEEH?GFDCCABBI?E?A1IICEGCBHI?CD%CB?HGFBAAEIECEF@DI
@>chr21:9543361-9543498-1
TCAGACGGTAATCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGTGTGTGGAGGCGTCCGGAACAGGAATTGGCATCTGGGTGTGGAGGG
+
?@DHBBBHBAEEEBCGHHA@H?HCI@GIBBI@B??I@IDH@GCADG?@@BGFF@DCBCIHGCH?FFHGAFCH@IAHHFAFGF??ADGE?F?FHCIIFE?I
@>chr21:9543361-9543498-2
TCAGACGGTAATCTGCCAGGCACCCCTGGGGACACCACGGGGGACAGGGCCCTGAGTGTGGAGGCGTCCGGAACAGGAATTGGCATCTGGGTGTGGAGGG
+
AECGH@DGAFCCEDBII@??HGGAGAFG?FGFA@E?FCE@DGIHDEAB@????G&EB??GGEDGC?ID?H?B?BGHEBBDIHIDA@?BHCDFHGGEB@HI
@>chr21:9543361-9543498-3
TCAGACGGTAATCTGCACTCCTCGGGGGACAGGAGAAGCAGAAAAATTCAGACCCAACCAGCCCTCCACATCTAGATGCCAATTCCTGTTCCGGACGCCT
+
DICDCEDDCCADG?AEI@IGIF@ECFF/F??FAHE?CBACCBBACIIGFHAE@AIBAHGBGEC?FCEHGA$@%CA@HE?@?FHD??EID@GHABHE?G?H
@>chr21:9543361-9543498-4
TCAGACGGTAATCTGCACTCCTCGGGGAACAGGAGAAGCAGAAAAATTCAGACGCAACCAGCCCTCCACACCCAGATGCCAATTCCTGTTCCGGACGCCT
+
BHFBEHBIFCFEE?FEH?BG?@FIGD@IBCEFG@ABDHC@HCFDC@HH?DIAG+@G@BDAE?E@IAB?A?HEEE@ECDHA@IED?FEDGEE@IF?@F??G
@>chr21:9543361-9543498-5
TCAGACGGTAATCAGCACTCCTCGGGGAACAGGAGAGGCAGAAAAATTCAGACCCAACCAGCCCTCCACACCCAGATGCCAATTCCTGTTCAGGACGCCT
+
?AIFFBDEFD?@H9GDCGDFEADAA@IBA@DC?DD?"E?AC?@CGGCFD?EC@GB?FDH?IBIADBEBBACFIHEHC@CH@IFIDA?@CDI8BFE@@CDF
@>chr21:9543742-9543805-0
ACCACTATGTCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGCGTGCAACCCCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
?CCHC?DCFIHIC?HBCGGFDHI@DEGGDD@EDIC@BBCHIGI@IGBEDBFBE@1BDFEHFD@A@EGE@CBFCHGEHCFA@GFEADFCFCA@?@@@AGHF
@>chr21:9543742-9543805-1
ACCCCTATGTCTGCTCCGTNCCAGGAAGAGGAGGAGACACCTAGAGCCTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
HBA/A@@@E?H?DI@FIDE&?CAACAABEDHE?BGIBI@??CEDAGEEFDEFD??I?CD@CHCE??HDIGIEFE@HBBD@DGBA@?BGFDAAHBDFHAAB
@>chr21:9543742-9543805-2
ACCACTATGTCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGCCTGCAACACCACGGTTCGCCTCGCTGAGATCGGAAGAGCGAAACAAAAAAAAA
+
BAGF@?B@@I@IG?@?FBDDDEG@F?G?H?GIIG@FBFIBDIHEHFBGFGBFGGFBAIDAF#BHAIAI@HICA?FAG@BAHGDHEG@??B6DDDBDAE@I
@>chr21:9543742-9543805-3
ACCACTNTGTCAGCGAGGCGAGCCGTGGTGTTGCAGGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
HFAFGI!EA@CCC@GCCI?EGH@AAH@?AIGBH@C@EIFA?AED@@DEIB@?BBDFA@HG?HBH?ADDFEIII@FCEEAEHGGC??CBCBDDHC@EIHDB
@>chr21:9543742-9543805-4
ATCACTATGTCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
I%BIGAC@DDEBAGA@BHBCF?CIGIE?IF?IEIHEG@EBCEGH?HBED@DI@F@?@HBIFDEDEGCFDGGFAHFAH?BAFEBHGCADEHFEEFCG@@I@
@>chr21:9543742-9543805-5
NCCACTATGTCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
7CIF@EAEABDBDG?GIADHGG?BCBE@@HIEC@@B@I?GBIHEEAI?EACBIEDADEBIGIEAFDH@FHHCAI@AG?EEFA@DDFBAFBCDGCCGC@@H
@>chr21:9543742-9543805-0
CTCATACCACGCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGCGTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
B@FA@FIIBHF@BDFGFEDDG?@BH@I@FAFBEB@HGIHGHID@GA@C@GI@BHFECCBAIHIFCBADAADII?IIBH@FC?IEFDG?@HFAEDCIFEEA
@>chr21:9543742-9543805-1
CTCATACCACGCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAACCTGCANCACCACGGCTCNCCTCTCTGAGATCGGAAGAGCGAAAAAAAAAAAG
+
D?GECGH?EF@H@DEDFGEAH@F@HEIDI@AEB@AH@A@G?DF?IH4HGE0D@'AFABEBEFBFC/GAFE2BB@AF??DFEE@HFIDCCBB@BCF??CI7
@>chr21:9543742-9543805-2
CTCATACCACGCTGCTCCGTGTCAGGAAGCGGAGGAGACACCTAGAGCCTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAT
+
A?BHAAGDICAAHCFAABHII.EEBBICF/A@DE@G?DCE@ACIGECCCCEFH@I@H@G?@FBHACCHHCE@?@GFBFBADEBHF@F??HI@BFDAGE?6
@>chr21:9543742-9543805-3
CTCATACCACGCAGCGAGGCGAGCCGTGGGGTTGCAGGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAGGAGCGAAAAAAAAAAAA
+
?BHEBDCFBHI@IGAAADEIDHECGHCI@.BHHFFDBFBC?GDCAFI?I?CBAG@??DBGFEGEFDDFDCFDBADGI@A@?@%BECCEAGBDDBCEGGEA
@>chr21:9543742-9543805-4
CTCATACCACGCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
DDGG@HBDIHEGAHE@IB@?FH@@E?CICFEH@HEHI?CADGHI@@IFIDA@EG@BBD@IFEBBDEGHGECHHCF@DDBHIACEAI@IBEIA?E???A?D
@>chr21:9543742-9543805-5
CTCATACCACGCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
F@BFA??ICBBCDFHC@@@?@DCBDD?BDFDEEID?DI@IEGEAAGGHH?AA@DBCEEGG@HGAIGBCFBII@A@?GFEA?GH@CFFHC@F?E?B@HBFD
@>chr21:9543742-9543805-0
GAAGGTCCTCTGCTCCGTGCCAGGAAGAGGAGGAGACACATAGAGCGTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
BCEH?@GABEC?CE?B??GHIFHCECBC@BD@HEHHIFC3?FCC@CDCAH@IAAC@FAGI1AAABF@EB?IC?@AHGI?BEB??D??EIIEBHH?@BDIB
@>chr21:9543742-9543805-1
GAAGGTCCTCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGGGTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAATAAAAAAAAAAA
+
BGG?C@DAD?AGCFIBHIAEFAHCGDC?I@DI@D@CCHGC?AGDA>GIHDHDBD??H@H?@HDDBBFF@IHA@CEBDDBABCG?E?@B&ABHFIHF?GGH
@>chr21:9543742-9543805-2
GAAGGTCCTCTGCTCCGTGCCAGGAAGAGGANGAGACACCTAGAGCGTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
FGGDHCHAHBBADDCGGIDCAICFCD?HHE@,@EAEFBGCHDI@EH?A?GF@E?EECBAF?AA?BAEHFEHG?C@HCICFDGB@H?CEBBHCHH?@GE?D
@>chr21:9543742-9543805-3
GAAGGTCCTCAGCGACGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAGA
+
DECHDDCBCF@GIDE,IIEDEGGG@GDGIABIEF?DHGEIAIHFC??BHHDE?CIEBGGHCDGFH@DIF@HFCHBIIIGAGE?@EGGGD?AGC@FC?F,?
@>chr21:9543742-9543805-4
GAAGGTCCTCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGCAGAGCGAAAAAAAAAAAAAA
+
DIFAE?DHF?BI@AF?DE@BADHGABI@DD?BBDBDCE?DGG?EB@EIEIIFIABEABECHAIG;FGCIGH?DF@GFAE!CFFI@IFHBCI?FDD?HEIH
@>chr21:9543742-9543805-5
GAAGGTCCTCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
IA@?@IC@AAA@EHBEABED@5AD?E@ICIGCDEH@DIECCBAGCEAA?FBC@EI?FGI@GDEADBEF?HBDFCI@DGGDECCFGE??GE;ED?HGIBHB
@>chr21:9543742-9543805-0
GCGGCGTACTGCTCCGTGCCAGGAAGAGGCGGAGACACCTAGAGCCTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
CHF@AG@CH??F@I@GHBGFFD@G@@?BA.?GGIBCDAIBEFEHCEHADGGGDFDD@@GBGGIEHGFFDDFD?BCGGH?GIHE?FE?G@FI?FIHDGIHG
@>chr21:9543742-9543805-1
GCGGCTTACTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGCCTGCAACACCACGGCTCGCCTCGCTGAGATCGGAAAAGGGTAAAAAAAAAAAAAA
+
E?@GC'EF?IH?EFGAADDC@?IIAEGBFB?AFB?HACCGFHE?BFIDC@GEFDBH?BIGBEAFC@@II@?FE???B@FC8?I3F*A@CDICEB@A??@H
@>chr21:9543742-9543805-2
GCGGCGTACTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGCCTGCAACACCACTNCTCGCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
FIC?C@EF@EHIIC@HAI@GIGE@F?DF?AEABFGIGFFDAFDHBGEHF?HG@AAGB55C@D@?ECB?H@DIIBAAC@FBH??DCDGHICAHG?CIFGHA
@>chr21:9543742-9543805-3
GCGGCGTACAGCGAGGCGAGCCGAGGTGTTGCAGGCTCTAGGTGCCTCCTCCGCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
IAC@BCHFAHBEA?BHGCI?BBD:@D@IDG?I?C@@DEH?C???.HB@?EFF(HBA@BEIDFEAIID@EGDCIIEEFCEA?ECEA@B@ABIBFAFIDBI@
@>chr21:9543742-9543805-4
GCGGCGTACAGCGAGGCGAGCCGTGGTGTTGCAGGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
GFHD?IGCEIAEBIDDEGE@GF+@@GA?IGECIBEGCCDICGI?G@GH@@EAFA?CEIFFAEFIFHD@IFDBGBIBABAGDG?HCFBAB@CGBIB@GDB?
@>chr21:9543742-9543805-5
GCGGCGTACAGCGCGGCGAGCCGTGGTGTTGCAGGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGTAAAAAAAAAAAAAA
+
C?ED?GBC?@EH?;@DC?CBGHG?GD?I?IGA@IACCBCCC?IFF@HF?@?FHEGCB@H?BBCDHAEDADAF?BBECBBF@@EDA"AAAIFD?AACIAC?
@>chr21:9543742-9543805-0
TCAGACGGTAATCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGCGTGCAACACAACGGCTCGCCTCGCTTAGATCGGAAGAGCGAAAAAAAAAAA
+
EGHIF@HFHE?AAIBIGFHB?CACHGAD?@GGFGFD@GIG?@H@CIEBBGHBDD?BIG.@DA?I@DCFBEBGGG$FFD?GCEIC@GBEF?EHB?@?@G@D
@>chr21:9543742-9543805-1
TCAGACGGTAATCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGGGCCTGCAACACCACGGCTCGCCTCGCTGAGATCGGAATAGCGAAAAAAAAAAA
+
BAG@BFDC@@ABE@EHCI?CIAABGGIDDCFBEEBHDGE?@G?DFE)@@@?BB??CHHGF@BHC?FBIH??IDFCBDCGFBGBG0GHIDHEAHGHG?G?G
@>chr21:9543742-9543805-2
TCAGACGGTAATCTGCTCCGTGCCAGGAAGAGGAGGAGACACCTAGAGCCTGCAGCACCACGGCTCGCCTCGCTGAGATCGGAAGAGCNAAAAAAAAAAA
+
BCH?BCEIHFCB?BHG?@FGCA?IIHH?#DFDBCCE@CFCIDBBCAF?CEEGHF6AAFBIEFBA?AHIAAH?AFIDHBFGAAGCHBHE9IHEFHIBBEBC
@>chr21:9543742-9543805-3
TCAGACGGTAATCAGCGAGGCGAGCCGTGGTGTTGCAGGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
@B@GGIC?CBDDIFIH@@@??FBCGD@@G?FII?IAHGCC@BGBD?DG@ACADICCBHGC??EGGBCIECBCBGFEA??FBDGDFDGCA?ACHDFE?CDC
@>chr21:9543742-9543805-4
TCAGACGGTAATCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCTTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAC
+
AFGAG?BIIE@FG@AAH?@C?@FFFEEGH@?DCIIHEA?C@GAIBH?ADH??;CHAEIIBAG?EECIDGGH?EFFH@GGAC?EFACEGBGBE@IHI?DF4
@>chr21:9543742-9543805-5
TCAGACGGTAATCAGCGAGGCGAGCCGTGGTGTTGCACGCTCTAGGTGTCTCCTCCTCTTCCTGGCACGGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
GHGIFBH@BIAHIEB@EADAIAGEIEDGDGCCFD@AII@@?HBDGAABE@IE?FH??IIFCB@FHHIBH@HEEDF@FC@CDF?C?HA??F@FA?HAFD@A
@>chr21:9562163-9562361-0
ACCACTATGTCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGNAAGTTCTTGCNGGATCAAGAGAGCTCTGCTGGGCCGGCCTG
+
??BDC@@ICIFIAEHF@IDGCA@GEFIGFFBCGA@IEEHBI@H?I?CFFIGICEDEEA,'EHDFDF)F@9ICG?AHBH3@D@ED@EBBFAFG@!I?AIHA
@>chr21:9562163-9562361-1
ACCACTATGTCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGATTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCCTG
+
?BD@?C?BIEBCDBI@CEECA?@BGAHBC??BI@AIIFGDH@ABEIF4I?CIBAG@A@HEGIIBAHHHIII@AECBCFECICAHEHB4FBGB??FCDIIB
@>chr21:9562163-9562361-2
ACCACTATGTCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCCTG
+
DBFGGD@CE@?H?@EHG@GHCDFA?BDBBBBCEHGB@HCFDFFAADIGI@@?DIGDF@I?DADC?AAGE?B@BDBBEG?D@GCIA?GDEEEHIAIDCDFA
@>chr21:9562163-9562361-3
ACCACTATGTCAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAGGTGTC
+
FBI@BHFC@F?ECBAIE?@IEI@DB?CBFAAG@?AB?H@GDHIEHA@@?EAFGGFBCC@IBIHD@EFDIG@@GHD?HEDEGGFBECF?BECBEH@CEA?G
@>chr21:9562163-9562361-4
ACCACTATGTCAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAGGTGTC
+
BEDHAHIE@IBFIECI@CA@?F@BAIAGGHCAIB@B?IAGDHDDGAEDAGH@@GDCG@HHD?@BFCABEDG@C?FFGFBECDEHFIDIABG?G?EHG@G?
@>chr21:9562163-9562361-5
ACCACTATGTCAGCCAGAAGGGGTTGTCTTGCCAGCACGTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTTGCTCCTCAGGTGTC
+
IBFGADIBDI?FEACA@GH??DBCGDC@@2EAGAIBFD+B?EBB@I?DDFCFCB?I?AIGH?IHCEDI?GI@ACH?FFGBAEBE@!ED?E?FG?DDFGD?
@>chr21:9562163-9562361-0
CTCATACCACTCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGTCAGTTCTAGCTGGANCAAGAGAGCTCTGCTGGGCAGGCCT
+
?A@?D@@GFF%?FBBCG?AD?EBH@FE@EDGFFGAIAAGFDAHH?IH@F@DBIECFFIDD@EIGH@CHCAIABG6C?HI@@BC?AFDCDCHF?FF??HHF
@>chr21:9562163-9562361-1
CTCATANCACGCAGCCCATGATGCCGAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCCT
+
AIFHD?4IEHC?EBB@A@AEEDA?B!HGHBIBHIA?IEGCCFCC?EFCA@BEHBDE?AF??DEG@HHCIBDEF?@ECAHDIBBGHGHEDDFF?G@CGCA?
@>chr21:9562163-9562361-2
CTCATACCATGCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCCT
+
D@EIIDB@I.@FB@GBHBAD@FG@AHCFAHHGFCE?@AHGI@DEHBIBG@BFAHC?@@BABGBHHDAEBC?AE?I?FBFIADFFBHFH@GDIDCFEDFGG
@>chr21:9562163-9562361-3
CTCATACCACGCAGCCAGATGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTTAAGCAGGTGGAGGAAATTTCAAACACCTGGCTCCTCAGGTGT
+
?HA@EBCIBAG@GFII?BA,BAACBGBBC@B?ABDBA@CCDEFGFC@*AGECEBAGE3IHFEBFE@BFFEAEB@A@E?G"EDH?@?FHADBCABAHFEDE
@>chr21:9562163-9562361-4
CTCATACCACGCACCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAGGTGT
+
B?DBGGBD?HIHH%EBBCCHEFEE?DBD@@BB?C@GECF?F@BCG@G?GFEEAG??H?CBC?CGHHCA@CFIHD?IFF?FBFH@BIEFHG?HEFIIDICH
@>chr21:9562163-9562361-5
CTCATACCACGCAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCACAGGTGT
+
F?AHEG?@@ED?@EFCDDBHFG?G?IF@ACDABHGEICFEHFIG?EGCCBDACABBDFI@A@?CHCF?FFIBGFBEDB?CCDHDEF??IHEC+CIEG?@I
@>chr21:9562163-9562361-0
GAAGGTCCTCCGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCCTGA
+
FFC??DEAEB"IBGH@@@F?ECCGFDAC@DG?HAE@GDFCGIH@GAAGAB@GDDA@D@?FBGCFHCHIBIC@BBD?@I@CGGDBCHEIFCEDHACC?AAI
@>chr21:9562163-9562361-1
GAAGGTCCTCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCNGCTGGGCAGGCCTGA
+
ACBDA?AFAEBIGBAFEDFFBFDCCFAD?CIE@DAC@HFHHBE?IHFHDFCDIHACC?FBI@HE@HIGEH?ACAIBE@IEECIA"DAB@GGAIHB@@@HI
@>chr21:9562163-9562361-2
GAAGGTCATCAGCCCATGATGCCAATGNCTACACATTCCTGAGTGCGTCAGTTCGGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCCTGA
+
BAAEDDG0BDEEEFF?AFD@@B?EE-I6FIA?B@EEAHDE?DB@D"BDC?G??G;D@IDDGA?GI9BBIGF@E@@@DBFBCE?GGHEIFD?EGD@C@BHB
@>chr21:9562163-9562361-3
GAAGGTCCTCAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAGGTGTCT
+
BHI?IAAHF?A@AGA@FFC@G@D?FAI@IDC?ICHHIEC?@DFEGEDGFGGGIHECDBG@I@@DEFFD??@?ID@F@DE?H?DABCFGG?IH@CAEID?G
@>chr21:9562163-9562361-4
GAAGGTCCTCAGCCAGAAGGGGTTGTCTAGCCGGCACCTGGGCTTTGGCGCGCCTGAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAAGTGTCT
+
ECGBGBB@GHHH??BEDCAICBG@DBI@AEF@0BF??HIGBI@A@I@GHD?7HFB=?AIDBGICEECCA@GAII??GF?HA?BCEIBHB?CE?8DEEGCF
@>chr21:9562163-9562361-5
GGAGGTCCTCAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCNCCTCAGGTGTCT
+
@'@CFBA?A@@AEAIIAECA?GH@EB?FA?HHFGCCACCGICAGFDI@AC@EE?FGAFIA?G?GCEDF??BCCBH?@HCDBFG@CF?)??CH@F?IEDBD
@>chr21:9562163-9562361-0
GCGCCGTACAGCCCATGATGCCAAAGTCTACATATTCCTGAGTGAGTCAGTTCTGGTCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCCTGAA
+
@?@0I?BFBGC?AFEECAB??DAHGDH?F?@C0EBHF@B??IADHCIDH@DHF@CGG?FIGAC@IAHAB?GB@ICB@HG?G@EFBGEGDICBIIFCFHC?
@>chr21:9562163-9562361-1
GCGGCGTACAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAANAGAGCTCTGCTGGGCAGGCCTGAA
+
?@BDAIECCED@DEDBBII@AAAGH@HGDDGHBGEFIC?@DGAEHIEI?HDHFFHD?EFBDBI@GFEEGG?@IDD<AEHCFADIICDDAAFG@EB?ED@F
@>chr21:9562163-9562361-2
GCGGCGTACAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGGGTCAGTTCTGGCCAGTTCTAGCTGGATCGAGAGANCTCTGCTGGGCAGGCCTGAA
+
@IEBDEHFGCFGEHGEICCC?AG?GHG@?CEIGEAEEAHHGGF?"DHDAHEGIIHGEGAECBCHCC?FHA?AC/IDDGD)?C@GDHFEBC@E@FA@BHGC
@>chr21:9562163-9562361-3
GCGGCGTACAGCCAGAAGGGGTTTTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAGGTGTCTG
+
DHAFGGDAHCGCA?EE?@EFBF@)CICAHE@D@B@CEFEBFDECBBFIEDIFIEI@DGCEAHFCGFE@FGDIEHCHDCEB?@@IDBEA?@CCCBACGGGH
@>chr21:9562163-9562361-4
GCGGTGTACAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTNAGGTGTCTG
+
HHE?0DIII@?@A?BFGAFEGCCGBIGABFGGD??CB@EADAC?EI@CB@B?ECGH@AAD@@@@@DE?EHA@GDHDDFB?DC@G@EDAF@)AHEBF@EGI
@>chr21:9562163-9562361-5
GCGGCGTACAGCCAGAAGGGGTTGTCTAGCCAGCACCNGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAGGTGTCTG
+
DE?AGD@HCBI??FBC?7?FIGICICI?GDBCFBHGD.EGHCAC@B@G@?IG@FCBIGFFBGIHFBBFF@B@GCCFAEFGACDBGG@IHB?EIED@BBAI
@>chr21:9562163-9562361-0
TCAGACGGTAATCAGCCCATGATGCCAAAGTCTACACNTACCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCC
+
H@HCHEIF??@ABIICIH@I@HIBABEDCIED??GCD.?#@C@??EDDCHCDFGBAD?GH?DB@@G-AIAHDCHCGC??BCEHH@AE?BCEEC?E@EIEH
@>chr21:9562163-9562361-1
CCAGACGGTAATCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAATTCTAGCTGGATCAAGAGAGCTCTGCTGGGCAGGCC
+
.BDIEDEF@G@@EF@ACGEDCB@BAAICBCEIBFC?E?@@ABGHEBCDCEIDG?@BBIAHBGH&ICEI@IGEADCBICIH?FCDAGB?CID@E@CDEA@B
@>chr21:9562163-9562361-2
TCAGACGGTAATCAGCCCATGATGCCAAAGTCTACACATTCCTGAGTGAGTCAGTTCTGGCCAGTTCTAGCTGGATCAAGAGAGCTCTGCTAGTCAGGCC
+
GEHD@IDBGAFCH?CFCE?BA@H@C?@GDGEF@AH?GB??ADDD?ADDHIHFDIH?DHCB@AF?BFGHI?AACDC@?@@F?AAIHFIBIEF"B0GCG@BF
@>chr21:9562163-9562361-3
TCAGACGGTAATCAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGGGGAGGAAATTTCAGACACCTGGCTCCTCAGGTG
+
?BGCDD?EDHGI@A@BF?HGID@?BFAD@@BBABGFHEBFA@GG?B?GACC??C?HCDB?HHA?IG3IH@ADCBIBHEE@FCFA@G$@GDGD??DFC@GF
@>chr21:9562163-9562361-4
TCAGACGGTAATCACCCAGAAAGGGTTGTCTAGCCAGCACCTGGGCTTTGGCGCTCCTCAAGCAGGTGGAGGAAATTTGAGACACCTGGCTCCTCAGGTG
+
AFI?E@?IBC@ABH*FD@HGD#DF5HEAEHBCAFDECEFDIGFBCCFBG?ABAC?BBFAF?IECAE?CGIIEEGCEFA!BBGF@@E@IDGA?I@CIGFFH
@>chr21:9562163-9562361-5
TCAGACGGTAATCAGCCAGAAGGGGTTGTCTAGCCAGCACCTGGGCTTTGGCCCTCCTCAAGCAGGTGGAGGAAATTTCAGACACCTGGCTCCTCAGGTG
+
BEBE?EIFBAIFIC@AHEEFDHIGFEBACFCCAHCICDHHBEEHAHDBA?@?:IF?EHGGIAHACC@FFIIFI?EEHE@CCEDBFFCID?HEIE?@?GCI
@>chr21:9570080-9570247-0
ACCACTATGTCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGTAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAATT
+
AA?I@IGECCACBDCH@C?EDEFC@IG@@GBHDGBHGDBFCAF@FIF@@DAG-GEGEH@C@IGEHBCIAA?AFDBGEDBBDAG@FHH?EBAI@BDDFH?I
@>chr21:9570080-9570247-1
ACCACTATGTCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAATT
+
G@@IH?@F?GHH?AHD@E?AG@CFGC@D@GGFA@HIHGFGCEDBIG?IEE@CDAFHHDD?GI@DHFH@FGHBE@F@G?IFAEAEGH@@@DA@GB@DGGAC
@>chr21:9570080-9570247-2
ACCACTATGTCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAATT
+
DE@@I?FG@E@?HA@E@A@ECAEHEI@DBFF?BG@FFIF@HHCGBDFHF@FFBCDDEBAIG?GEE?@IEA?DADEIGI@BBDGGEBHBC?FBCDFABIIF
@>chr21:9570080-9570247-3
ACCACTATGTCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACTCCAGCCTCCCTAGTGGCTGGGAGTATTGGCATGCTCAGCTAATTTTTTCCTCC
+
FBEEBDB@CG?DGDBEDBECAEIBABH?@FH?CCFDDED@EIECHI+/AIG?CFIGCBBDBI?GAAGGC@GDEGGBB?HC?BC@HBAFBEFEHGAAAIBD
@>chr21:9570080-9570247-4
ACCAGTATGTCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTGGCTGGGAGTATTGGCATGCTCAGCGAATTTTNTCCTCC
+
BH?C(BHAIGAGHH?DGCCE?GCDDAHI@?DH?ABBFGFGIEHDB??FH?DDIGDEHBBEGBBH?GBCBEGHGCGDBFDEBGH@DG$BGF@ID=AHB@@B
@>chr21:9570080-9570247-5
ACCACTATGTCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCTTCCCTACTGGCTGGGAGTATTGGCATGCTCAGCTAATTTTTTCCTCC
+
I?DCFHADGGGGDCCE@HHGEA@F@AHCDHH?BIID?BCBHCG?CF@CECGD5@FEBID(@?GHHDECAABCCEF?EI@ICBIGCHGFC%BAAAIECEFE
@>chr21:9570080-9570247-0
CTCATACCACGCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAATAGGAGGAAAAAAT
+
I?HCBAIFEAHFDIEDDBBAIEDBCDADF@DDEFBH@A@BGAAB??IEII??IEACII?@@HADE?CCAGD@BIA@DFCID@HFHF7AEDDHEBHB@?AA
@>chr21:9570080-9570247-1
CTCATACCACGCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAANAAT
+
DFGACA@DGDA@@?GHDBH?GDABCB??F?FFGDFD@DCFHHBDHFADGFCB?A?BCIF?H?ACHAF@IGB/IIABGEIIEDGFDF?DGCC??A?/3AEF
@>chr21:9570080-9570247-2
GTCATACCACGCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGNCAACATAATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAAT
+
%DCACBIHHGEDCDFFAHI??E?CDECCDGA@C@EDI?IBD?D?EIFDBCF?<ACABII/GHG??DBDADCHEIHGFFDH?IHE?@DCDFFGFBDI?D?E
@>chr21:9570080-9570247-3
CTCATACCACGCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTAGCTGGGAGTNTTGNCAAGCTCAGCTAATTTTTTCCTC
+
FFEG?FH@FCABCEIDBB@I@C@EDA@DGICC?FBGHH@ADGD@CDGH+?AFI@@IB?@?HHHHCFFG??H@*DIF!BH*AEE??CBDDDDHDAAEDGBI
@>chr21:9570080-9570247-4
CTCAAACCACGCTGCCTTAACCTCCTGGGCTCAAGCAAACGCCTCACCTCAGCCTCCCTAGTGGCTGGGAGTATTGGCATGCTCAGCTAATTTTTTCCTC
+
HE?I2FCBH@FFHEEHG?HIGBIGF?FDBHIAAI?EA?HAB&AFBFBGAIB@BB?@I@FC@BHAEICIICFCEHCAF?CBF?HAGF@@DHDBCIEEI@FD
@>chr21:9570080-9570247-5
CTCATACCACGCTACCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTGGCTGGGAGTATTGGCATGCTCAGCTACTTTTTTCCTC
+
EAICFA@C?FCIF:GF??@AFG?EF@F@BB?FFICD?F?HDEE?IFEIIE?BBG????DED@CD?AFBGAD@FECBHHDB@DHI?EA@F>BCA@AFFFDF
@>chr21:9570080-9570247-0
GAAGGTCCTCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAATTA
+
DGEGBI@ADC@BDIH@AH@IGBE?@B@CGFBD@AIAGFGEEGEAEIG@IA@AH?G?HF@BEI?GAAEBEACEF<GBH@G@?C@A@DB@@GAE?BCFGHBD
@>chr21:9570080-9570247-1
GAAGGTCCTCAGCAGGATTTCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAATTA
+
FFFH@FGC@FAHFFACFCC$IHDD?AB?DADCIHF@G@EFA@BFBBD@AC@??DHHFB?GFH?GFHBHCI??DGCC?CDG@IFB?CF?IEBFIBCC@@@H
@>chr21:9570080-9570247-2
GAAGGTCCTCAGCAGGATTACTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGCCCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAATTA
+
@BIDABBDF@BADFGG?D?&F@AFFA?GG?H@GFC?CBC?IIGC@A@@DABHFFF?BHE@?CA+FEIHGIIBBHDH-FEA??H@AHCBBC@FAC?BBEG@
@>chr21:9570080-9570247-3
GAAGGTCCTCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTAGCTGGGAGTANTGGCATGCTCAGCTGATTTTTTCCTCCT
+
EGEIBGBCFFCFG?E??C?IGHAE?AI@BFHAIEBGIBDAFA@F@FDEEHACF@CH?GFB?DDCDAGIEDD&EIIFFBCH?CB@D?;?CEEGEBEBDCGF
@>chr21:9570080-9570247-4
GAAGGTCCTCTGCCTTAACCTCCTGGGCTCACGCAAACGTCTCACCTCATCCTCCCTAGTAGCTGGGAGTATGGGCATGCTCAGCTAATTTTTTCCTCCT
+
G@@@GCI?H@FCEA@DCACEHE@FGBCCDH@2FAIFD?CE?C@BIIEBA+@FDFEDGD@FI@FFGHIEEAF@,G?A@@FA@B@FDEH@GIDGD@HHDHIG
@>chr21:9570080-9570247-5
GAAGGTCCTCTGCCTTAACCTCCTGGGCACAAGCAAACGTCTCACCTCAGCCTCCCTAGTAGCTGGGAGTATTGGCATGCTCAGCTAATTTTTTTCCCCT
+
E@AHDIE@HDECAAAHA?IIBCGBAGAG1DCHEAEGIHGBB@D@FCIHC??CAG?GC@@??IBF?B@CDBIB@@BECHD?GGG@A?DFAGDF?C=D#BAC
@>chr21:9570080-9570247-0
GCGGCGTACAGCAGGATTGCTTAATCCAAGGAGTCCAAGACCAGCGTGGGCAACATGATGAGACCCTGTCTNTACAAAAAGAAAACTAGGAAAAAATGAG
+
A@A@AGIBD??;IHG@G?FEFD%EFDH@@AF?AAFHEI@AEHHI?$HDI?B@GAHIC@AHADIH@DD@CBD#DB?@BIIAAFDCD=#DECGGHF??F'CC
@>chr21:9570080-9570247-1
GCGGCGTACAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAGGGAGGAACAAATTAG
+
IEIFGACI?EDHGH?EEFG@FAAID?E??G?HDG?IDHCF@D@ACDE@CEAAEDBIB@BDBHI@H?BFHFHAGG@CBHFABBAI)HF@HHBF%FABEBCA
@>chr21:9570080-9570247-2
GCGGCGTACAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGACGAGACCCTGTCTGTACAAAAAGAAAACGAGGAAAAAATTAG
+
BC@CAGF@ACI?I?BCEGACBIDFDIBB?BFCC@EBAGBEE8EHHB@EIFCDGCFEHE6FCEIBG@HCCFDBFBIGE@?GFDCDI3EGBFC@ACI@FEIA
@>chr21:9570080-9570247-3
ACGGCGTACTTCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTGGCTGGGAGTATTGGCATGCTCAGCTAATTTTTTTCTCCTT
+
'EBHF?CADG;HD?BIG?E@@AH@DBDDIEGBHC?IDCCHGH?H?ADIDBDEGIEEFA?DFIDEEDHCGH@A@HGHCIDBCDG@HBBFC?FC@9BHIE?C
@>chr21:9570080-9570247-4
GCGGCGTACTGCCTTAAGCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCATAGTGGCTGGGAGTATTGGCATGCTCAGCTAATTTTTTCCTCCTT
+
EIHGHBHHBGAF@HGBI5IIBIAHAD?IFF@??HF?GECEEI?BDDGCEEGHCB+FEEBICEIFD@?DABDDH?FH@DI@?@CFBCGI@IAGC@FEEIHD
@>chr21:9570080-9570247-5
GCGGCGTACTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTGGCTGGGAGTATTGGCATCCTCAGCTAATTTTTTCCTCCTT
+
FF@CADIEGF@AEFAHIHCEIFCEC?HGAH?HD@DDA?BBBAGEA+DGIBG?HDGFC@AFEGDBEC?BAGABGG?CH4AGC?BBADEBGCD@EBHDG@FC
@>chr21:9570080-9570247-0
TCAGACGGTAATCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAA
+
@IGGHBGIG?HDGFBHIIE?BICABEB@GHHGADG?BIIFABGAA?GIDBDECC@IE@DIAHGCCB@HAAGIFEAIACEDCIHIIEGDAEF@B@FCI?GD
@>chr21:9570080-9570247-1
TCAGACGGTAATCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATAAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAA
+
B??BB?@CFCGHGBIBCABFE@?IGIFBCBHDCAB?CAAB@GDHGBEEGBI@?@CFDDHACD?&GAIGHIHFHH@EGHDIHGBG@F?IFIFDHE?B@AF?
@>chr21:9570080-9570247-2
TCAGACGGTAATCAGCAGGATTGCTTGATCCAAGGAGTCCAAGACCAGCCTGGGCAACATGATGAGACCCTGTCTGTACAAAAAGAAAAGGAGGAAAAAA
+
GG?DDGEI@EI@FA@EFFHBHAH?FFCG@D?G?FDC@D@HIIGGFHHE?DCB@IHECCAHBEAEI?@G@AHD@A@GAEEHIGACA@HDFAGIBEC@@B@E
@>chr21:9570080-9570247-3
TCAGACGGTAATCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCTTAGTGGCCGGAAGTATTGGCATGCTCAGCTAATTTTTTCCT
+
F?@DH?CIBCHHCI?E@FDGDDHAI@ACHBG?@GHHFFG?HIIG?EBGFCHI@I?FBE5@GHFBGF!CB5BHB@HH@E?EGGA@@CAH@?CBAEH?FF@G
@>chr21:9570080-9570247-4
TCCGACGGTAATCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTGGCTGGGAGTATTGGCATGCTCAGCTAATTTTTTCCT
+
EC=H?C@BBECIFHI?GBIEAH?IF@EC?FICDCEC?HIBIFADIFEFCACEECB?F?DEB?FIBHGCIFGAHEIGBAC@GAGID?FFDHBGHADBBG?F
@>chr21:9570080-9570247-5
CCAGACGGTAATCTGCCTTAACCTCCTGGGCTCAAGCAAACGTCTCACCTCAGCCTCCCTAGTGGCTGGGAGTATTGGCGTGCTNAGCTAATTTTTTCCT
+
+GCCC?GACA@C@&F?FCEHAEGHG?BIIDAD?HHEDGF@HGIF?GIIFDAIGF?GBD@C(BICGHHEEAAECHIG@IB.AH@D&?GBHEHCEBCECBH@
@>chr21:9578082-9578218-0
ACCACTATGTCTGCGAATGACAAAATTTCATACTTCTTTGTATCTGACTAGTATTCCATTATGTATATATCTGACTTTTAAAATCTATTCATTTGTTGAT
+
CBICAGB?CECBHBCGD@?EH?ICCBBC@HBHCFCIB??B?HHCH@BBACBIC@FGAFFD??GADGIIDG4B@BGI@H@@@I@@IIHG@@CEF?CCBB@H
@>chr21:9578082-9578218-1
ACCACTATGTCTGCGAATGACAAAATTTCATACTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTGAT
+
C@G?BDBC@H?BD@?FI@C@@HD@DAGGH@IHDBIFDIIEIC@DDE@AHH@HFC?I@DBDDHH@FEBDIHGDFE?EDEB@IGGFBECBGECCIG?GEDAF
@>chr21:9578082-9578218-2
ACCACTANGTCTGCGAATGACAAAATTTCATACTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATGACTTTTAATATCTATTCATTTGTTGAT
+
DFHCDFH3BGIACEI@GC?GH?EHAFEGIHGCDHBFIIBDE@HA?HHGI?@GAADIA@BAEEF??GGAA??FCDDFDGFFB,E?DEIABEACF?G??HBB
@>chr21:9578082-9578218-3
ACCACGATGTCAGCACTATTCACAATAGACAAAATATGGAACCAACATAAGTGCTCATCTACAAATGAATAGATTTTAAAAGTCATATATATACATAATG
+
CAEGE,AFACGHI@BBAFIAG?BACIFDCGHCGDCDIEDIG'D?G?A?DCE@?C@B?DH>ICBGEGEIFFA?DFFCBGC@EB?EBE,F??@IEEEAEFDH
@>chr21:9578082-9578218-4
ACCACTATGTCAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAATG
+
@DGEDHAABHGHIHGFGAD?ABFCCAD@CIIDGBCGFIF@EDIDFHCGIED?BHCFFFAE@?HA@ADIGDGEFFGIBHCCDG?@EFEGF?GHABEICHHG
@>chr21:9578082-9578218-5
ACCACTATGTCAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAATG
+
@@DBA?IEB@F?EIFCB@AGCG:F?I@H@H?FCEHBHICI@@HCFAFDGBIHDAEDFHIDAB&CEDFDFD@CEIB??EBFI?FFIFFGGD?@CDCICDDG
@>chr21:9578082-9578218-0
CTCATACCACGCTGCGAATGACAAAATTTCATTCTTCTTTGTATCTGACTAGTATTCCTTTATGTATATATAGGACTTTTAAAATCTATTCATTTGTTGA
+
GDGI@?DE@DH@FDHDH,EDFC@??@G?GB?FB?F@DHCCDBIE?D?BEDHHEGBIIA;CFCDGG@EDA@AF-?G@FFBFA?H@BBFBBCH?GFFI*GED
@>chr21:9578082-9578218-1
CTCATACCACGCTGCGAATGACAAAATTTCATTCTTCTTTGTATCTGACTAGTATTCGATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTGA
+
BHAG@EG?IHG?CBBHHDGBBDGHDC@B@AI?FDHGB?CDCBFCA?IHGDDEGEBCH6EBCB?@FFB@EFB?BDHFHI@GBCEEAHF@EEF?@C@GB@?A
@>chr21:9578082-9578218-2
CTCATACCACGCTGCGAATGACAAAATTTNATTCTTCTTTTTATCTGACTAGCATACCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTGA
+
FAEHFE@BG@HCIDGACH@BCEE?D?BAE!IFCC?FG@HH'GIDFD@DAHBH$C?9HBGDBIABECD@CD@CCBEFC?@@AIBBGGGBBEHDGEB@CBGA
@>chr21:9578082-9578218-3
GTCATACCACGCAGCACTATTCACAATAGACAATATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAAT
+
&E?I?CG?HA@@BEGEEGIIADCHEDAII@ACA5CDAFDF?FGHIC@DGBFFAGEICDCB:ICADEDAIGCBAEFIB?@ICCHHBDGCABBFG?FFHB@G
@>chr21:9578082-9578218-4
CTCATACCACGCAGAACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAANAGATTTTAAAAGTCATATATATACATAAT
+
AICHCCGDGE?BIF,@?GFCCDBIDDEB?@GB?@ABGBGEHCIDFDE@ID?AHBCBC?ABCHF?A?CAGA-GG@DH?AEC@C?BGFCCHGGDG?HAFCHF
@>chr21:9578082-9578218-5
CTCATACCACGCAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAAT
+
FDAE?FHHD@BBAAI?,?DFC@$GA?GF@A??@IG?GEEHADGEHG@FBFHCG?DACBDEEACBEDGBBEHA@DGDBIFEABB?BH?IDG@IBAHG@BCE
@>chr21:9578082-9578218-0
GAAGGTCCTCTGCGAATGACAAAATTTCATACTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTGATG
+
IGHEAFHFDB?IB?CBBHBIFIBD?DD?@DHCAGFH@@DE@IAGEDFA@CI??BIEBGIDHAIFB??B?H@??EEIIBC?DIB?A?GI?BCBGHHFFCFC
@>chr21:9578082-9578218-1
GAAGGTCCTCTGCGAATGACAAAATTTCATTCTTCTTTGTATCTGACTAGTATTCCATTNTGTATGAATATGACTTTTAAAATCTATTCATTTGTTGATG
+
FGHF?HCIFCG@IAAIDCD@?@CDIEA@H?BDDBEBECGD@@E@FB?FGDHDGEGID@C4GGDFC06HBD?IHEE??DIFICCDADG@CBAEIGF?HFBH
@>chr21:9578082-9578218-2
GAAGGGCCTCTGCGAATGACAAAATTTCATTCTTCTTTGTATCTGGCTAGTATTCCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTGATG
+
FDGGI%IBCFGDCGAHGCA@?DHBD?D@DE?DD@HDHD@?DIH@G5AFDEFIIDCEI??HEGHHIDD@@DFEDEHF?EHI@ACCB@?DBI?DFIBDBDG@
@>chr21:9578082-9578218-3
GAAGGTCCTCAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAATAAATGAATAGATTTTAAAAGTCATATATATACATAATGG
+
C?BC(EDAF@DBIHICFH??GHEHCC??II@CGE?AAICC??FBEECCHFDBBEEBBEDG&DCGFC?EB@FBBGC?@HDGFHHE@@A?GHAGF?GI?HEE
@>chr21:9578082-9578218-4
GAAGGTCCTCATCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACAGAATGG
+
HBEDAFAAGFE>FDFIF?BEHCA?E?C@AIHAHFIFAAEFC?EBEHHI?@IAA@CDIIFFBH@EBDIGFBCIEEIEE@BEGID@A???DHA@H?,ID@C@
@>chr21:9578082-9578218-5
GAAGGTCCTCAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAATGG
+
??CBD@FGEBICE@HHAGA@GEEH@?F?EBFIG?BAH?GAEDBACI?FBABFHIG@BII??CCGGGG?@?AHDBFCIBAFAEC?FDADDGCCIGHG?A@D
@>chr21:9578082-9578218-0
GCNGCGTACTGCGAATGACAAAATTTCATACTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATCAGTTTTAAAATCAATTCATTTGTTGATGA
+
CH7BCIEAA@D?GGBBEBIIFDFCIBBA?FBGIADFI@FEA@GAGB@F@?BIF?@G@A@FFHGFBHGBG?.H%H??FBAHECI;AIIGBDIGA@IBACIE
@>chr21:9578082-9578218-1
GCGGCGTACTGCGAATGACAAAATTTCATTCTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATGACTTCTAAAATCTATTCAGTTGTTGATGA
+
GFIFBH@@HICC?EADAAHAHCHGIFA?IIIA?HBHII?BDIIGGGCIBIEIB@I@EGC?EFBA@IH@HFC@@FE;DCC?BD@?@@AGH!BBIBF?HDIC
@>chr21:9578082-9578218-2
GCGGCGTACTGCGAATGACAAAATTTCATTCTTCTTTGTATCTGNCTAGTATTCCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTGATGA
+
C??BI@AGI?@GH?BI?FABHDBA@GBFGECBDHCEAIBBEFB@!IAGACGBCIIDDGC??ECHAIEIE?IFDCEFHHBBHD?HBF?CE??IEDGCIIHF
@>chr21:9578082-9578218-3
GCGGCGTACAGCACTATTCACAATAGACAAAATNCGGAATCAACATAAGTTCTCATCAACAAATTAATAGATTTTAAAAGTCATATATATACATAATGGA
+
DDE?D?ADAAF@?EADEHIIBIGDIFCCBHHBE7%?HC@DCEEFGBBDGE3D?DIIHEB@DIFF7EFIEIFF?HGB?FAIGCGBI@ADDGGDFDC@@@C@
@>chr21:9578082-9578218-4
GCGGCGTACAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAATGGA
+
HC?GCCHAGF@FIFIDA?G?ECIDHBB?HEHG@EHD@?@G@GF@I*?CGB?GD4@AB?FFABAHD@AHACAG?:AH?A?BGCAH?FFBAHDE?G@EGH?E
@>chr21:9578082-9578218-5
GCGGCGTACAGCANTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCNACAAACGAATAGATTTTAAAAGTCATATATATACATAATGGA
+
DAGDHGDIDE@CD8BBHBBGGCEBCC?EDDBH?A#@CIHE@HBCGDD?C?GC@DFDA#DBHDB=CEA@EHHHBI?CD@I?B@?@H?DHFCGG@F@IHHG?
@>chr21:9578082-9578218-0
TCAGACGGTAATCTGCGAATGACAAAATTTCATACTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTG
+
DFE?GADGA?FBBGBFBCDHFD?EAAH?H@BH?BHBCA?IH?EC@AIDBCAIGDEIAAHHB@?GACIH@FE?DCCC@DDA@D@BGAHDIDAAEEDFH?CA
@>chr21:9578082-9578218-1
TCAGACGGTAATGTGCGAATGACGAAATTTCATTCTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTG
+
?H@?AGFAG?GA"AIBFAA@A?H1C??AEA??CCECH?HFCAE?AC@HDDFFGH!EDDGH?DGEABCDGAGIB@FGBGC@IIEFB@B?AIBHHDFDIHCF
@>chr21:9578082-9578218-2
TCAGACGGTAATCTGCGAATGACAAAATTTCATTCTTCTTTGTATCTGACTAGTATTCCATTATGTATATATATGACTTTTAAAATCTATTCATTTGTTG
+
?@BADBI@GG@A@FFG@CGDBGBI?H@ECEDC?BCII?HD@GC@DHHEC@DGE?DIDB?F?HIBBA?CGGBHGH?BG?ADA?HAED?ICBEAE@DAIIEA
@>chr21:9578082-9578218-3
TCAGACGGTAATCAGCACTATTCACAATAGNCAAAATATGGAATCAACATAAGTGCTCATNAACAAATGAATAGATTTTAAAAGTCATATATATACATAA
+
@AHIA@GHCHBIFDC?IC@I?I@ACEFFAA)GD@@?HGC?ADAB@IH?C?=DHE@HH@HG&EEDAH?FBCFGFI@?@C@7?D?IE@??AAG@CI??H?DI
@>chr21:9578082-9578218-4
TCAGACGGTAATCAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAA
+
HABAFCIGGC@BBID?G?DD@CI?CE?IEBBCFBGCBCIFFFBDBGIE?BECFBEAA@CE?C@@@HGH??A@HED?DBECH?EG@E@@HADFIFFAA@I@
@>chr21:9578082-9578218-5
TCAGACGGTAATCAGCACTATTCACAATAGACAAAATATGGAATCAACATAAGTGCTCATCAACAAATGAATAGATTTTAAAAGTCATATATATACATAA
+
BAACEGBH@G@BIFIFHGBAAFFEG??GGIEFBDFIHCH,H?FGHIGB?A@HDDI@D?GEBBD@?FCD@GGHAFEDA@BEB@@GDG?DGFB@EFE@FF??
@>chr21:9592798-9592882-0
ACTACTATGTCAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCTGAGATCG
+
FD;ECA?EIBEECCFE?A@BAE?GDCI@FI?GFFD?F@CG?BHFIBEA@BAHHEHI@BBDHGCAGDFDIDFAEBEEEEFHBIIH?BEDAEBB$FA?EBFF
@>chr21:9592798-9592882-1
ACCACTATGTCAGCTGGTCAGGTGGTCGTANCTGGTATTCATAACTACTTGCTTCCAATATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGATCG
+
A@DEBEHFGBHFGAG@DGFE?GDGCIC?GE)BCI?IDII2AHBHGECAIG=DCGFCD;?EIAA@BDBC@IBGDEIDCIBFC@BD@H?ICGF?GIEBHDB@
@>chr21:9592798-9592882-2
ACCACTATGTCAGCTGGTCAGGTGGTCGTTGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGATCG
+
BADI@BGFIIIDFAAHIIBBAHGIA@IG?'F?A@AG@IBGBF?GB@AIHEBIFFCGGBAFDEBECDHC@H@EICBEHBDABDCGFC@HCI@EBCHCDDFD
@>chr21:9592798-9592882-3
ACCACTATGTCTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGTTATCAATACCAGCTACTACCACCTCACCAGCTGAGANCG
+
HC?AF?C@AGFGCF@@AF@EACGGFDGGDE@CBE@ACFGBEGGCADACCFICBFD@@BG@BDDHI@?CI?I0DAH@@*CD@GA@@/HFFBEE?@H??.BE
@>chr21:9592798-9592882-4
ACCACTATGTCTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGTTATCAATACCAGCCACGACCACCTGACCAGCTGAGATCG
+
HFDDIII@?DAFBCA?H?IHIIIFIABCIAGFBCCF??AA@AEF@@BBA?GDF@FG@?HICA?F@DCEH?IDAC/CHEF?GHDCEBFDFGB@@CEHFEGC
@>chr21:9592798-9592882-5
ACCACTATGTCTGCTTGCAGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGTTATCAATACCAGCTACGACCACCTGACCAGCTGAGATCG
+
EAGCAGG?DABFAHFII?-?E@GGIAEA?DFACFA@B@@A?BIEGFFE?CEC??ED?CA?GDEI@HE@C?ADDAA?E?ICE?IBHBDIDI@DCAIBABIC
@>chr21:9592798-9592882-0
CTCATACCACGCAGCTGGTCAGGTGGTCGTAGCTGCTATTGATAACTTCTTTCTTCCACTATTCATTTTGTATTCCCTTTGCCGTCAGCAAGCAGAGATC
+
I@??H@DDDDAA@?DGDIAEFGGAIE?@GC?GAIGEFBB?HAIA@FD+BCDAHEBIEEF?ID?DGEE,DHBHAFHCH@GIDCF9HDC?ICGI@B@AIFD@
@>chr21:9592798-9592882-1
CTCATACCACGCAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTCCAGCAAGCAGAGATC
+
ECGCDBF@DCADDEGDHA?HHG@FFFIABGAAGE@2E@D??IGA?E@D?H?FAHFEIEC??IBHFAFD??@EAHIIEEF@@BEG$HCIGEI@@ADCCH@@
@>chr21:9592798-9592882-2
CTCATACCACGCAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCTGAAAGCAGAGATC
+
CGHDHBBGC(@GCFECDCACFEAEEBFIAACEHDEB?HGAC@IIGEC??HHDIFIHDIBCBA@GCCDBADBDEAH@BHB@HIGH@C+G>BHAH@?ADEIB
@>chr21:9592798-9592882-3
CTCATACCACGCTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGNTATCAATACCAGCTACGACCACCTGACCAGCTGAGATC
+
F?@@FED@G??EBDFDE?GI?ACICBDCD@C@DEEFI??AG?BD?DAECIGGGAIDHHGHD;H?BEFHHCIH@DHFAHG?FHCFAGEB"AIICGGI??DE
@>chr21:9592798-9592882-4
CTCATACCACGCTGCTTGCTGAAGGAAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGTTATCAATAGCAGCTACGACCACCTGACCAGCTGAGATC
+
?HEE@G@EIBACDCFBDBECFGG@F#EIG@?@@B@FIDH?HIBFIBIBEHH@C@DCEECHEAHEEHAI?@D@?GGC?IGAADAHAGH??I?FIGIH?E@?
@>chr21:9592798-9592882-5
CTCATGCCACGCTGCTTGCTGAAGCCAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGTTATCAATAGCAGCTACGACTACCTGACCAGCTGAGATC
+
GGBG?1B?AEHIEAHC??E?AHGF<DBAGGBCHI@D@HCGBDG"?CB?CA@@CFHGD?IC@I?CCGCHGAAGBEDIEHEE?)?G?FFEADHGHCHCGBAB
@>chr21:9592798-9592882-0
GAAGGTCCTCAGCTGGTCNGGTGGTCGTAGCTGCTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGGTCGG
+
EH?BDFD?@CC@AIDDCI2ACAEE@GGDIHB?I@@IGBHICD@0GIID?DIHAIHIG?IEAHBCCC@AFDGG?ADBIIFIEAEAAIAHFBFCGGC"CC?A
@>chr21:9592798-9592882-1
GAAGGTCCTCAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTTTGTATTCCCTTTGCCTTCAGCAAGCAGAGATCGG
+
HHBEDCAABCIHEE?D@DD?CHHCC?FBIEAGEDGHDHBHEFCIDEABI?DCGBH@GGHE?FDC?(D?ACC@H@?AEDAIH@ICADAGIIEG@ADBEIF?
@>chr21:9592798-9592882-2
GAAGGTCCTCAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGATCGG
+
?DCADFH?CC@@IBID?GC@G?BCGAHCHIDGFHDHDHAB@?BABD?H?CGD?EFE@@H@=EBBI??BEABDD?D@@BH@B?HGAADHEAIFFCIHF?GF
@>chr21:9592798-9592882-3
GAAGGTCCTCTGCTTGCTGAAGGCAAAGGGAGTACAGAATGAATAGTGGAAGAAAGTAGTTATCNATACCAGCTACGACCACCTGACCAGCTGAGATCGG
+
CCEEABH@@ABG@?DBCF?CEG@@GDIHGA@:DDIEF?I??HBHFIAGGC?DAFFC?HAIFEA@;A@DAHHC?FAHCGFCAIIH?FA@@C@IE@ICB?GB
@>chr21:9592798-9592882-4
GAAGGTCCTCTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAACGTAGTTCTCAACAGCAGCTACGACCACCTGACCAGCTGAGATCGN
+
IFCGG?ADHEEDIBCIECAACGHC?@@CC?AE?EIIFDBDDF?EDAI?IAABED(FDAIHC+I@EI/H@EEHHBECFFFIHDC@C@DEAGFIIBADDIC,
@>chr21:9592798-9592882-5
GAAGGTCCTCTTCTTGCTGAAGGCAAAGGGAATACNGAATGAATAGTGGAAGAAAGTAGTTATCAATAGCTGCTACGACCACCTGACCAGCTGAGATCGG
+
DEE@HCDH8FE7EDCCEFC@@G@ED@ECECH???F8BEEE@AACEEHHAHG?IIHIGBB?BEC?G?FFIA/FA@?ECECDCIFG@?EI??2A@BBEFG?H
@>chr21:9592798-9592882-0
GCGGCGTACAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGATCGGA
+
?D?ED@ECIH@HAGICC?H?ACIHGEHGFGAEIHDGCEACGCFDHGHHC?GDFCHIAI?CGAE?IDIGI?FFEG@?DDEBGEFCFAEBIIICBBCHHHD@
@>chr21:9592798-9592882-1
GCGGCGTACAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTNTTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGATCGGA
+
DCCBCDEIDBF@FHBCFG?IGGI?ACAA@DH@?BICIFE?E!GCEHFICE@FGFFA@,FDDIDBBGI@@GG@?I@G?E?IFICDHEEFIIB?B?BDAI?F
@>chr21:9592798-9592882-2
GCGGCGTACAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGTCTTCAGCAAGCTGAGATCGGA
+
?FCF?FIH@II@IA??F?HEG@BHEG@@?AG?GAHHABDBAGBCFAF@EGHEFFCG@FIACGE?CHHIGDFBF@CDA@=FFIHE?AHE?@4??DBDEAEE
@>chr21:9592798-9592882-3
GCGGCGTACTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGTTATCAATACCAGCTACGACCACCTGACCAGCTGAGATCGGA
+
EEB@CEF@FHEFDCI@ACIIFGBIDCHFDDCIAFGAFCEE@CED@@BIC@I@?GIB@AAG@HBDFIB@H@IHF@F@HDDH?ICGCG?@CAIGGAABCI@B
@>chr21:9592798-9592882-4
GCGGCGTACTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAAGTAGTTATCAATACCAGCTACGACCACCTGACCAGCTGAGATCGGA
+
CIBH?G?FDEIFBCACEBGBHI?EIBAIFI?AEIG?@EFG@GHEDFFF?HEB@IGBEIFIGD@IDI?IFIBH@?BAFHEDHFC*ADGAAGIGE?AH@?FE
@>chr21:9592798-9592882-5
GCGTCGTACTGCTTGCTGAAGGCAAAGGGAATACAGAATGCATAGTGGAAGAAAGTAGTTATCAATACCAGCTACGACCACCTGACCAGCTGAGATCGGA
+
EAG-=G@CIFEDGBIDI!BHF?AAC?@IFHDBGF?FCC?B8GHBHHIEHFGHGHG@AI?EFDD@BCIEFF@D@BGEB"@BIEDDCFDGCDEEC?H@HF?F
@>chr21:9592798-9592882-0
TCAGACGGTAATCAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCCGAGAT
+
DCECEFFGGHB@FD@DBEIECABCFFDE@GFICHBAIC?DCDHBA?ACIE?IADACHG?F?BIACC@ACHEECCGDIDHEHEA?FI@@??@ICG+E@HD?
@>chr21:9592798-9592882-1
TCAGACGGTAATCAGCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCAACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGAT
+
HEGIEEAHABEE?CB?FCFCECDF@FDBDECGCBBGIFAFCGAH@GF@?ABDICAHB"EBE?DGDF?IFIGBAEFB@BBHFGI?3IDDIAIGHGIBD?B?
@>chr21:9592798-9592882-2
TCAGACGGTAATCATCTGGTCAGGTGGTCGTAGCTGGTATTGATAACTACTTTCTTCCACTATTCATTCTGTATTCCCTTTGCCTTCAGCAAGCAGAGAT
+
CGFFG@I@BGC?HI/BH?GFBCAIFHB%HAGIBDGFEBFGIDC@ADDHDIBCFFEHFHBIGBF?HGCFGAB?@EGDEEE@IGAI@IEFGEDAGH?GAAED
@>chr21:9592798-9592882-3
TCAGACGGTAAGCTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAAGNAGTTATCAATACCAGCTACGACCACCTGACCAGCTGAGAT
+
ICDC?@ECC@?5IADHAE?@IIBI?EACBBFE@GGF@AHGBBEGDHI?EDHDECF?IAB;CGG?@FAAGHEEC?HIIBB?CHI?IBIDI?DHAH?ADF@B
@>chr21:9592798-9592882-4
TCAGACGGTAATCTGCTTGCTGAAGGCAAAGGGAATACAGAATAAATAGTGGAAGAAAGTAGTTATCAATACCAGCTACGACCACCTGACCAGCTGAGAT
+
IH?ICAEGDIFCG'E@A@CF@I??DHC?CAIB?@ACAC?DI??,FD5FEC?FFGABIAHHBFG?@IGDFACDC?B?F?GG@@@HBACG@ACHIFIDCBAE
@>chr21:9592798-9592882-5
TCAGACGGTAATCTGCTTGCTGAAGGCAAAGGGAATACAGAATGAATAGTGGAAGAAANTAGTTAACAATACCAGCTACGACCACCTGACCAGCTGAGAT
+
HHHCDGEED@DACEABHEHBEIHFHHBEEH??EGEFEIDDB??HBIDDFHCCAA@EGD!CHA@IF0CE?HECDCFA@ACEC?GEBGCIEBIFB@GA@???
@>chr21:9594626-9594815-0
ACCACTATGTCTGCTGTGNATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTGACT
+
@HH@G@EDBHD@DBBBGH/BBFBBFDCGCICFB@GADH@H@?C?CAI@BEE@?CDGH@AH?IF?FAEAFDD@AAHEDBCCFA@HICGCIH@E@DHFFFBG
@>chr21:9594626-9594815-1
ACCACTATGTCTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCNCCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTGACT
+
D?EBE?HGCIHI?EIBCDIHHFAI?DEGD@AEGDG?@B@@I?I?ED?ACI?EG'IDBCHI@AGEBBCFAG+?DCCDFH@DEFHIFEFHDH?BFBBBCIED
@>chr21:9594626-9594815-2
ACCACTATGTCTACTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTNACT
+
E?DHBEAF@EI@'@HBBBHHDFAD?ICFFAHAFAGBDBHHIBIFD?BDA@B?DB?HGDA@?@DEFICDIHHAHFB?FGCHA?BFECBIFCC?F??G,@DB
@>chr21:9594626-9594815-3
ACCACTATGTCAGCAAGACCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCGCTTGTCCTATACTGGGCTTTTGTGGAAACTGAATAT
+
BHDDC@ACDCEF@BF@C5ICHHEI@@ADIIHHB@DEHBEGDGCDC?DFGBCDHHBBDA?ACHD*HEAFFBFF?AHIBEGBGDF@A@B@?HH@I@CFACDB
@>chr21:9594626-9594815-4
ACCACTATGTCCGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTNTTGTGGAAACTGAATAT
+
EAGGADFEDCA?CIFHHGCEAFCGDCG?BAHDCHIAC?HCEBEHI@CDDIAGFFDC@BBBCCCCDHC@FFAAIDD?E@HEFF<BHEDI?IAHBHI@EEDI
@>chr21:9594626-9594815-5
ACCACTATGTCCGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGTAAACTGAATAT
+
AA?IGEFACCDEEAI?AF@HGFH@I?IGBEB@I@?BD@CI@@B@A@CBIIEDE?HAC@?HDABGDE@AC@?FBB@EA?DBH@?A?B@@+CAFDF@BAIDE
@>chr21:9594626-9594815-0
CTCATACCACGCTGCTGTGCATTACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCAGGGTGACTTGTTGAC
+
BBDHFDHBAHD@F@CEGDF?HC:@DGDFCHAE?EHHCBEAEIHBEEGCCCIIIHFECEFAEGDFGAAFEBGEEF?D@CH?HHBE@<EIGFH?D@E?BGB?
@>chr21:9594626-9594815-1
CTCATACCACGCTGCTGTGCAGGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGAAGTTCAGGTCGCATGGTGACTTGTTGAC
+
?A?DFGHD@DC?EIE@?IFDI<HCIDEHIEDFAB?GD?II?GAHIBBIHBGCAFADAB?CDFCBDIIIH?C-CHBHEE?HAGAIIIIACDHA?GDHDEIA
@>chr21:9594626-9594815-2
CTCATACCACGCTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCATCCAGTTCACGATAGGCAGTNCAGGTCGCATGGTGACTTGTTGAC
+
BIEC@@IGI@DH??HBDC@GC?HCCFCGIEGFEFEF@@FCIBCAIEB?EFDFCBF!HD@BF?IHED?@DAHGHDD,FE@IAFEHBEDFCDAFG@CA?GCH
@>chr21:9594626-9594815-3
CTCATACCACGCAGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTGGTCCTATACTGGGCTTTTGTGGAAACTGAATA
+
FIC@ECCCC@@HCEF?BDH?CCA?@AGFFFHHBGEA@HGEIAIGCGEGIBDAGFBFGICI@@HBBFE)HHFBBHDHDHEHHBHEIACHA?ICGAECCAA?
@>chr21:9594626-9594815-4
CTCAAACCACGCCGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGGAAACTGAATA
+
FEDF)?GEEBHF??BGGHGAGBAFB@HAGF@@CFIBFAIG@GFEEGIE?HIDHBAAGFCIFED?ABB@@FGACCHG@DF?GI?@E?AE@GAGC@FDG?BI
@>chr21:9594626-9594815-5
CTCATACCACGCCGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGGAAACTGAATA
+
?IBIIEFBFI@HBDBEEHGEE@F?FHHI@IAFHACHIE@BF@@AHB4BCIA@FGCF@?DGAH@GIFG@A?GHFC@ED@FG?IIFIF@EAG?DHD?FFB??
@>chr21:9594626-9594815-0
GNAGGTCNTCTGCTCTGCATGACCCACTTTATGGCTNCAAGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTGACTC
+
F)EFDHF(@GA?H?3GE@?EH@FDDIHDB?HAHDFD$AG&BFFIDADIHDABHFIHBAAFF@C@CE@CH@B?IHDHFF@AHGBIAFEHH?G?ABBIBIBI
@>chr21:9594626-9594815-1
GAAGGTCCTCTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTNGTTGACTC
+
CCDBEIFC@?EHEGFHAEC??GHAAHIA?BFG?FCEA?EBEAIDCAFADDEHE@ADEGEEHADHDAAACGG@IGDIAADGAABID?BE@HC'DBDDCHA@
@>chr21:9594626-9594815-2
GAAGGTCCTCTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTGACTC
+
H?BD?IAC?IDDEH@IIBFFA@IHDD?GADF?EBFBCADEHBB@BCG?BAA?B?B@E??GCAEFF@CE?GCCB@GCAACCAI?H?ACFEECH?GG@BDDF
@>chr21:9594626-9594815-3
GAAGGTCCTCAGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCTTATACTGGGCTTTTGTGGAAACTGAATATT
+
CA?BHCC@BEGHIDBIGG@E@ICA@IDIC?CFEA@CCHGBFBH?IGI?DCFGHGEFHAHFDIE@BI?BC*GHI@IBAB@C?BIFDAFIIA?GIHBDGHCG
@>chr21:9594626-9594815-4
GAAGGTCCTCCGCAAGGCCTGGTCATCTTCTCCAGTTAAGTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGGAAACTGAATATT
+
EHHIDIFGCIBBAAEACEBEABCEDC?HIAGBFHCCBA?'AHHEGDIFCHCHAGFBDCFHGE?A@GAGFB?EECFGDGFCIGA?EGAAGDCGFG?HBH?F
@>chr21:9594626-9594815-5
GAAGGTCCTCCGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGTCAGCTCTTGTCCTATACTGGGCTTTTGTGGAAACTGAATATT
+
HEHHAB@DBAAH@HAEH?GFEDC@HIAA@BA?CE?@?GH?H?E@IEAFBHFF?DBHE:BBBCA?FAGHFEG?ICF@I?IIGBABFFFDD?FCAAFE?I?G
@>chr21:9594626-9594815-0
GCGGCGTACTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTGACTCA
+
DHFGHA???D?IEC?CB@BCFDC?IADE?FBGCHI?@EDBIG?@EEGBGDIEICCFEFD?CFDI@DDFFFB??GEECEAIIHCAFGADGEDH5IB?@EAE
@>chr21:9594626-9594815-1
GCGGCGTACTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGCCTTGTTGACTCA
+
GE?E@DHCHIE@DCI?EEFC@CHBD@DAEICIGH?BDAEAGGEGE@CG@A@ABBD?BAHI@FDGA?G0?@EAIHADIAGFCIDEGBA0DGA??ECB@G@G
@>chr21:9594626-9594815-2
GCGGCGTACTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTGACTCA
+
CED@A??HDFB?FGDHHDCIHFEADBHBAIHDHFDI?BCBGEICEHIC@B?FHBDB?CDDGGD?IHEGFFEIBH@@GBADACDCE?GFEDI?CFIBCEHC
@>chr21:9594626-9594815-3
GCGGCGTACCGCAAGACCTGGTCATTTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGGAAACTGAATATTT
+
@EGAFIC@CHEEGFB1C@AI@GDEF&A@@HDD@IA@CCFEHCAAFDCCGDG?IH@?GHHDHBFGIEEICDHIEGIDIIEBGG?I@IEC?DAFHB?ABCFI
@>chr21:9594626-9594815-4
GCGGCGTACCGCAAGGCCTGGTCATCTTCTCCANTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGGAAGCTGAATAATT
+
??IHDF@DI0DFCD@CGE@?DAHGAG@E?@EHH.BA?GCBDGBCFC@@A?BECAFIFAGBGIFHEFEICDD?FCDC?FEHGGCBDEI@?'EGGFDIC<HA
@>chr21:9594626-9594815-5
GCGGCGTACCGCAAGGCCTGGTCATCTTCTCCAGTTAAATACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGGAAACTGAATATTT
+
BAE?C?IIBCDCIFGEIH@B@A@CIFCA@AHECIDFBA"EHE?ABDIAH@ABHD???DBBDC?C?BG@GCHFBIEAA?BA@EDB@?H@@GECAEE@CEAH
@>chr21:9594626-9594815-0
TCAGACGGTAATCTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTTGCATGGTGNCTTGTTGA
+
A@CEIHBF@BAG?CCBEHABCBIE?D?DI?HHEAHEHDIC?ICDII?A@GH?GEFCEDDGHFDAIBGB@FCBHB?F?BHD?@>EADGEHH@(AGICHACC
@>chr21:9594626-9594815-1
TCAGACGGTAATCTGCTGTGCATGACCCACTATATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTNGA
+
FBECCBI?IDE&IIFIBA?D?D@A?HFGFFG#EGGAG@AA?FBGCFACG@IGHFD@FDBH@AAEDAII?@AEDA?BGGB?EIDAHHDGHHAHH?BFA!IF
@>chr21:9594626-9594815-2
TCAGACGGTAATCTGCTGTGCATGACCCACTTTATGGCTACATGAGTCAGAAAGCACCCAGTTCACGATAGGCAGTTCAGGTCGCATGGTGACTTGTTGA
+
D?A@EGGBHGEIHBG@G@ADDBGCHEF?EFHGG?HAG@?DCEBBAIDIB?C@CCBC?BBECBCFAIFHDE?BHF@CAEHHGEBGHDEHAHHADE?II?EH
@>chr21:9594626-9594815-3
TCAGACGGTAATCAGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTGTTGTCCTATACTGGGCTTTTGTGGAAACTGAAT
+
A@DHAE)AGIECIIIHEI??BH?CFGAAIDCCBAHGCFF@B@I?DCDHD?IFDFEEH???GBAGGA2D>F?FBH?F?EEE?ICHBHBGDEHDE?ECABA@
@>chr21:9594626-9594815-4
TCAGACGGTAATCAGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTNAGAGACAGCTCTTGTCCTATACGGGGCTTTTGTGGAAACTGAAT
+
AFA?I@HCB@CE?ACEFEFAH?CEIDBA@?G?IH?DGDD@DG@CIIABC@C@BAF$HACACDFCACCBEBBIAI@AA?:?@DCDHAGG??HCF?BA@DCE
@>chr21:9594626-9594815-5
TCAGTCGGTAATCAGCAAGGCCTGGTCATCTTCTCCAGTTAACTACTCTCCTTTTGAGAGACAGCTCTTGTCCTATACTGGGCTTTTGTGGAAACTGAAT
+
BDAD3?EFBFCHCEAEF?B@DGBAAFGGH??CBFG?HE?@GHGA9GECIIDG@FHFII?FI?BIHABDGGHDEIGGAF@AGIIAF@?FC?EI@FGIIEFA
@>chr21:9594812-9594876-0
ACCACTATGTNTGCAAAATATTAGAGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
CDHE@CHB@F=?ECIGIGB?GIEBGEDEDD?H@FA@FH?ADAFIEDABHBGIIA?BEHHAH@@FGFEHGEFF@IA?E@IHEIGFF?A@CBCHHEHBC@F?
@>chr21:9594812-9594876-1
ACCACTANGTCTGCAAAATATTAGAGGCCTCCACCATGATTCACCNATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAACAAAAAAAAA
+
D@FB@??.@AH?DHDCABF@@AFIIDBEG?CGCAH?HBID?I?GC<FC?AGCBD?DEIACBDICGIGIGCGGF?AF?GFAFCGEHHI@G?&H?EFCFIDA
@>chr21:9594812-9594876-2
ACCACTATGTCTCCAAAATATTAGAGGCCTCCACCATGATTCACCTAAGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
A@?IFD?C?I@?=CDEDHCB?G@?EH?EHAAAIDEFG?@CGGDEGC@0C@?DCGHGIHE@CCAGBE@?B@FBHBEA?EHC@IAEIACDEF?I@FGI@GAF
@>chr21:9594812-9594876-3
ACCACTATGTCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGCCCTCTAATATTTTGCAGAGATCGGAAAAGCGAAAAAAAAAAAA
+
CICFBFBEFFIC@AEFBGFFIG@FIBDCCFIEGAD@?DACABA@IADEA?DHBCAD<???EC@EEEI@F?F?CIDFDI@G?GG1@?@FIDFIHG?@HDEF
@>chr21:9594812-9594876-4
ACCACTATGTCTGCTTTGAGGCTTTGGCAGGCCTCAATAGGTGAATCATGGTGGAGGCCTCTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
FGHIC?CDEFBEHIDBFFGB@A?GG?I@ACAFGHF*DA?CBCHGICCEFHB?GDCBIAHFB@G?AFIB@@AFCACHDI@A?IDIIIEBDDBCAF?F?G@D
@>chr21:9594812-9594876-5
ACCACTATGTCTGCTTTGAGGCTTTGGCNGGCCTCCATAAGTGAATCATGGTGGAGGCCTCTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
B?HCGDDDFEBI@D?ACCBAGEBBGIBF6'I???IF?DD.@FDI@CCBAFFE?BGA?CDACFEFGCDIFAAI?H@A?BG@BFAEDHBD@HB@CIAB@EIG
@>chr21:9594812-9594876-0
CTCATACCACGCTGCAAAATATTAGTGGCCGCCNCCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
@HEAG@HFHIA@CDACDFHEEHDDIFD@FH<B@8EFEDIGB?DCFFEFFGGBBCHEH?ECGBDIIHCHBDFCFD%GBB?DADECFI@ACHHBGFDBDBI@
@>chr21:9594812-9594876-1
CTCATACCACGCTGCAAAATATTAGAGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGTAAAAAAAAAA
+
F?EFAFHD?AHEFFCBDAAII?@BEEI@HEAAFAEBIG@ADIG@AHGGCFDGH?C@FHB?@EACBHDGDHG?CABDCBDDG@FDEE@B?=?CC@IDAHIG
@>chr21:9594812-9594876-2
CTCATACCACGCTGCAAAATATTAGAGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGGAGACCGAAAAAAAAAAT
+
+GHCBEAH@?HFCFC@FCA@?@HIFDCCHFI?CDGEBDCEE@IHBGGD@?FDHAIHBFBAFH@?HACEI?EEEFGDDDBGHD8I@B<DD@?GE?EGE@@2
@>chr21:9594812-9594876-3
CTCATACCACGCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATGATGGTGGAGGCCTCTAATATTTTGCAGAGATCGGAAGAGCGAAAAAACAAAA
+
GACIF@I@HEHHBDE@@GHDEIBGBE?IE@<FFFBFAEEIFEEIEDF-GCD?HEFHA@FHI@E?FBGEIAEBGGE?CHBC@FEGDFGBCF@C?CD'GG@C
@>chr21:9594812-9594876-4
CTCATACCACGCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGGCCACTAATATTTTGCAGAGATCGGAAGAGCGCAAAAAAAAAA
+
EIEE@AFCIB@FDCDBDEFGAFFI?CEBABBEF@HBA?B@@AHCACE?ACAFD?HAEBBIBAD@EFC@GCDAIDED?IBC?BFBFIAGE1EA?B?I'HDA
@>chr21:9594812-9594876-5
TTCATACCACGCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGGCCACTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
#@IDBH@A@HFEGIGF@DFAB?CFEFFB@DC@ICB?BIFA@FHGEDH@IHIDBB?DHIGAD@FC@E@C?@@AFFDGAE@BCCCBBDIIBHCIHFEDH?FE
@>chr21:9594812-9594876-0
GAAGGTCCCCTGCAAAATATTAGTGGCCTCCACGATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGNTCGGAAGAGCGAAAAAAAAAAAAA
+
EEG?CDDB3AFIBF?DCIBCGGEBE@C@IF?HH*?H??@DAFGCAGIGDEED/FCBCI@?F@F@BCIIFCBCEGG&BBCA?HFD?II?BH@BFBDIGHGB
@>chr21:9594812-9594876-1
GAAGGTCCTCTGCAAAATATCAGAGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATTGGAAGAGCGAAAAAAAAAAAAA
+
EE@ED@F@ABIGA?G@?HFA)?FHFEBCGDDEIFCDIHAEHEHIHG?EEBGF?B?BG@FCH@GFGAAA@FH@CCDFG2GEBAEG@?AFB@HGCA@EBDBC
@>chr21:9594812-9594876-2
GAAGGTCCTCTGCAAAATATTAGAGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
AIIBFE?GEB?EF@A@FIB.EIHIHAAA?ECDDAFEIHHD@?FGFDFI@G@BFAHFGDGGIHI?F@EH?CCABF@@HGFHHDCADABECDFGC@EFGEFE
@>chr21:9594812-9594876-3
GAAGGTCCNCTGCTTTGAGCCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGGCCTCTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAANA
+
F?B?AHCI,D?B??DGC@H!BCCFDHBB@??IHFIDDDGG@?GDDB@HCC?C@DAGEC?BC?BCGA?DACI@CHICIFIFCC@?DEGBEHCEADEDIG6A
@>chr21:9594812-9594876-4
GAAGGTCCTCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGGCCACTAANATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAGAAA
+
G@H?GBAFE@GAI?HAEB@BHF@GACAH@HIGCGFCGB?@IA@@E??BGB??G@EHFCBFA?A.BEC@?BA?BEGEF@HDBAFIBC?CB?BBHEDB*?CA
@>chr21:9594812-9594876-5
GAAGGTCCTCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCAAGGTGGAGGCNACTAATATTTTGCAGAGATCGGAAGAGCGAAAAANAAAAAAA
+
IHCBGF@G@HB?CDC@FBAFA?I@DEEGEB@D?BFDIGHH?A@HAGG4IBI@ABDHA+ECG?BIBDBEGCF@GHDGIDI@BIHEIHCIAAHD+FE@AIBI
@>chr21:9594812-9594876-0
GCGGCGTACTGCAAACTATTAGTGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
CDFIIFBB@?AH@B?$IGAC?HCBHACIDHAECIAGCDBFAGBGCGEBDGCDE?ACCG?EG?GHADHBGH?CDCCECCCDHBC@DCE?EFEHFBF@IB?A
@>chr21:9594812-9594876-1
GCGGCGTACTGCAAAATATTAGTGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
ECHEE@GGG@CGF?CHFEF@EHGC@AEHFGGH?C?<BECHCDBGHEAEEI?@IBGHI?HIAH?ECBIICIHH?HBE@AB?FFBC?DHFACA?AB?@HG?I
@>chr21:9594812-9594876-2
GCGGCGTACTGCAAAATACTAGTGGCCTCCACCATGATTCACCTATGGGGGCCTGCCAAAGACTCAAAGCAGAGATCGGAAGAGCGAAAAAAACAAAAAA
+
CCFFCDICFC??FEAH@F1G@BAFBHEC??CD@?A?EGFA?FEBDCF@>@EHEGEHF?@?D-IIIBH@HFDFHEFIA@BD?ED@DIHCBAHEE3@BCE?D
@>chr21:9594812-9594876-3
GCGGCGTACTGCTTTGACGCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGGCCACTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAGAAAA
+
FHEABFFGEC@AH?C?H7I@C?CAA@CF@CBG?G@E@HFECFEDFDHHIDGAAIB@EFDGEHBDEIGIFDIIADB@BB?IIBF@?F?FD?AGG@G/C@FC
@>chr21:9594812-9594876-4
GCGGCGTACTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGGCCACTAATATTTTGCAGAGATCGGACGAGCGAAAAAAATAAAAAA
+
GHA?@DB?A?HF@BECCE@HH@CAAFBFC%GIAGI@ABD?CAGHBG?II@HFABEDA@HC@IHFEIEAGFA@AIFGEAD@3IDGI@GA?@?CD(FCAGAC
@>chr21:9594812-9594876-5
GCGGCGTACTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAAGCATGGTGGAGGCCACTAATATTTTCCAGAGATCGGAAGCGCGAAAAAAAAAAACAA
+
@@H?C@GFDF???DEHH?BAIHBA@AA@IAIF?FD?AHHDF?H+@?EFFDAAGHHCIEDIBI@CI?@H+@?AGDCAIHDD@H4EDA?CFFCDD@ABF-@B
@>chr21:9594812-9594876-0
TCAGACGGTAATCTGCAAAATATTAGTGGCCTCCACCATGATTCACCTATGGAGGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
E@?@@CGHFHCIEI+IEEDADAB@EF?IGABFAHII@IIFEBCCBIIAIDFCA?HEBBDCDIF@BABFBFDCFI@DIEH@I?@IHICHH@IEIAEAECCB
@>chr21:9594812-9594876-1
TCAGACGGTAATCTGCAAAATATTAGTGGCCTCCACCATGANTCACCTATGGAGGCTTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
GDGHHB@CE@EE@IGIHHICGCAECEE?AF?I@CHFEB@BD-?AAACBCIDBGGFF&IBG?EIFHHI@EABCDBCIF?DCFEAEHAIBAEFCBBGIBBE@
@>chr21:9594812-9594876-2
TCAGACGGTNATCTGCAAAATATTAGTGGCCTCCACCATGATTCACCTATGGTAGCCTGCCAAAGCCTCAAAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
@AEDHD?HC4ADIHAECH@EGBIDIICIAG?HDEHBICDBGCFBIEE?A@H@&*F?IBGCCFC?ICFBGIICAADEHECG@AEGFIIBDBICHBD@GECD
@>chr21:9594812-9594876-3
TCAGACGGTAATCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCATGTTGGAGACCACTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
DIDDGG?ABFD?D@H@CACE?CFC?FIBEE?I>CCD@FBIBCECA?GEHG?F4@FGDB-FF?EFD?BBBIDBEIFF@EFHGFA?C??FCHCA@E@FAAAG
@>chr21:9594812-9594876-4
TCAGACGGTAATCTGCTTTGAGGCTTTGGCAGGCCTCCAAAGGTGAATCATGGTGGAGGCCACTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
AGAGI?IEDAA@HIEACADE@CIFEDCF?@BEBI?G@IC9DAG?B@FFIDAHEAG?DICFEHAIFFD?B@FC@GADGDAF?HCD@?FC@@AI?AIBC?@H
@>chr21:9594812-9594876-5
TCAGACGGTAATCTGCTTTGAGGCTTTGGCAGGCCTCCATAGGTGAATCATGGTGGAGGCCACTAATATTTTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
@GHHDEFAGECI-FIAECBAE?DDGFAIEHHDHDHEFG@CHH?IF?IGHIFII?F?@GGDHCCI?@GFI@@HGEHAFHEG@EDIIAFB?B??AA@CE@@E
@>chr21:9646367-9646455-0
ACCACTATGTCAGCTCTACAGAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAGAG
+
FEB@EG@GE@FGIAIA?GGDFA@C?GG?BBDIIICAA@FAHCHDBC?AGCBFGIHDI?G?BEADI@BIF?@AHBI@IFHG@@@?B@?HFBFGH?FFGH@@
@>chr21:9646367-9646455-1
ACCACTATGTCAGCTCTACGGAGGCATTGGCGGTGTTACATCCCTGCATCCACTCCGGCAGAGCAGGGGGCCCTCCGTGGGTTGTGCTCCCAGAGCAGAG
+
ED?BEHFIA@BCBIACFICEFHHIFDCFIEFCFA@@?GAB"E@FI7AE?BHIGE@HECGHI+ECCFGD!HCE?AABGEDDDCFG?GGCBEBI?CHAFIGG
@>chr21:9646367-9646455-2
ACCACTATGTCAGCTCTACGTAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAGAG
+
?IEFBAG?DBHHDDCEH?AE/@BDHEE@I?AGIDHAD??CFIBH@EHEGEI?ABEIDEH@FHCHGCGBGEFAIIC?EEH?C?F@CCC?I?GI@FCEIEA@
@>chr21:9646367-9646455-3
ACCACTATGTCTGCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCCGTAGAGCTGAG
+
IHHEDID@DCGDF???@IHAIFBCH?BHHAABAIAHHBBGDBAGAHGFIHDFGFHGFEIDIAEEHDEADIC@BAABIAHACGFG?CHHDA?@?DCFGEIB
@>chr21:9646367-9646455-4
ACCACTACGTCTGCTCTGGGAGAACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTGAG
+
G?FBGFB$@@DECHFAH@B@GC4HEHGADADBIA?BFHH?@?GD@E?FFHHGC?HC?DAEH??DEAIEIHHGEECFCDHB?H@FI@I@FHBF?GI@DDC?
@>chr21:9646367-9646455-5
ACCACTATGTCTGCTCTGGGAGCACAACCGACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTGAG
+
GEF?H?GGCFBCAHE@DIAE@?G?DAEEC6CFADBHDC@IEGB@EFHDCDD@BHAAIDHD@?IEAEFFAC?G@I?HDIFDHBFCIAABHGAI?FECGICB
@>chr21:9646367-9646455-0
CTCATACCACGCAGCTCTACAGAGGCATTGGCGGTGTTNCAGCCCTGCATCCACTCCGGCAGGGCAGGGTGNCCTCCGTGGGTTGTGCTCCCAGAGCAGA
+
@AIAACAGFIECE?DG?FCGAEBBCIAI@FGHEHBEC?$CEBFECAA?CG@CBAAI@DFDFIEIF?AFEEC>H??AHEBFCI?@AGIB?FH@HCC@GICA
@>chr21:9646367-9646455-1
CTCATACCACGCAGCTCTACGAAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTACCCTCCGTGGGTTGTGCTCCCAGAGCAGA
+
@FAAA?@EBFA?HEABCIH@E8EFCAFIHBBHDEC?A@?DE@FIG?ADD?F?GEA@GDFBAIDIBACHAB6@E@H??BD@CC?FI@BG@HFB@@I?CB?@
@>chr21:9646367-9646455-2
CTCATACCACGCAGCTCTACGGAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGTTTGTGCTCCCAGAGCAGA
+
HB@>IB@GB?GGEBHAC@GCGCCAE?A@FDF@GGBFHDCAB@H@?AFEF@@H@IBHBCFIFFAH?BHCBIBHCEFF@EF@H:IDHFHF@BEDBGEFCD@I
@>chr21:9646367-9646455-3
CTCATACCACGCTGCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGCATGCACGGCTGTAACACAGCCAATGCCTCCGTAGAGCTGA
+
CI?FAGDBD@CC?EBHCBEIBDHA@B?E?EGEDHDDHCBCICEDI@IBEEG@GI?BDBF&C@@CF.ACDEBDEGFAG:C?CFCDEF?EIHCHADG@IHFI
@>chr21:9646367-9646455-4
CTCATACCACGCTGCTCTGGGAGCACAACCCANGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTGA
+
HIHCAHEEEBEAFDEHHGI@HFFG@0B@HFCD;CG?BHFH@ACIDCEBDFIAIEF?E@GDCDIDIBCFAFFG??AC?AACH?GDDADBGII?FD@@AFDC
@>chr21:9646367-9646455-5
CTCATATCACGCTGCTCTGGGGGCACAACCCACGGAGGGCACCCTGCCCTGCCGGACTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTGA
+
?CGGC?!AF@AGD@GAHICDH&FIEIFICHCEDIGD?FCBG?@CDFGECI@DC?DI&ADECGGAD?F@@HFDBDDIICFIDHEDACBFAD@HHGHBDHED
@>chr21:9646367-9646455-0
GAAGGTCCTCAGCTCTACAGAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAGAGA
+
AG@DBECAIFBHBBIFGGF?GCA@CHI@EEDDBF?ECFGB?CGDF@GFCAHAF@@DHI?IIBFDGEDA?EIF?GG?AGCFI@G@CHDC?BB@B???IEDI
@>chr21:9646367-9646455-1
GAAGGTCCTCAGCTCTACGGAGGCATTGGCGGTGTTACAGCCCTGCACACACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTCCTCCCAGAGCAGAGA
+
HCFFECGBGHGFH?FEDBGIB?AH@E?G@@CACECIFA?ACBDCFFI#1FEBBB?I?BD??F@CD@BBFH?H?G@IADBDD@GB=??HGEFF?CBEI?DD
@>chr21:9646367-9646455-2
GAAGGTCCTCAGCTCTACGGAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCCGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAGAGA
+
E?BHBFAIHAAFHCGB@IGGAFCIFDIAG?EGIEBIC@HHIBADGGAIFEFCDGICEF*I@DAB?EI?IGA@BI?GEG@AADGAGIEE@EIEC?BHII@C
@>chr21:9646367-9646455-3
GAAGGTNCTCTGCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCCGTAGAGCTGAGA
+
?@G?G?+?D@@IEEGEEADH@IHFHAGD?GCF@CIGIAGDBDFA@GF?DEAED@D@?@IBG?@C@BDCFG?C@AGHHEAIBEEFHGB@HCB@@D@HIEED
@>chr21:9646367-9646455-4
GAAGGTCCTCTCCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTGTGA
+
FD@C@@BBCC@0AAD@AGHBEF@HIABBGF@EDHHE?B?CHC@?DACD@EDBCFDABABHGDHFBCI@AFICBIGECAHG@A@HCHFFADDHIECIC!EI
@>chr21:9646367-9646455-5
GAAGGTCCTCTGCTCTGGGAGCAAAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTGAGA
+
F?GGGHH?H?B@HEED@IE?B?A;FD@?FAF@@?H@D??EIBIFFFI@I@F@EEBHF?IBD@?@EIB??IIFDIDGGBCDDIA??FF@D?FBIG@GEECD
@>chr21:9646367-9646455-0
GNGGCCTACAGCTCTACAGAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCNCCCAGAGCAGAGAT
+
D:BII;FE?B?DGBHFB?F@HIHIBG@ICBEBHA?B@HDCCA@FHFFCE@C@EICABECFB?DEC@??@C?@G?B@GCCF?HCCE*BIBIBDIBEGD@@A
@>chr21:9646367-9646455-1
GCGGCGTACAGCTCTGCAGAGGCATTGGCGGTGTTACAGCCCTGCATGCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAGAGAN
+
DG@ID?CFEIBB?EI+HDFDBCBGGACAD?G?A?IBB@DIHEDGHGA9HG?FG@DD?DD?E?EICEBC@@CHC@ACHGIAAGCIH?DDIDFACCEEIAI9
@>chr21:9646367-9646455-2
GCGGCGTACAGCTCTACCGAGGCAGTGGCGGTGTTAAAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAGAGAT
+
DDHIBEAAEFGIDGEAC8GGIBDH&CBF?@HFA?CG<FA?@GFGEH?ACAHCHICGECEEFI?D?ECBE??BDBCCCBAADD?IFDIDBGBAEA@FA@?I
@>chr21:9646367-9646455-3
GCGGCGTACTGCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGAGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTGAGAT
+
DECFFBECBIGCFDGBGDEABAFCI@AGHCGGGFIAA?@A@@CB?CACI?BHBB$BEIHI?ADEEH8AAACIHD?@GBDEGHCAGHGAEF@F?FG?CCED
@>chr21:9646367-9646455-4
GCGGCGTACTGCTCTGGGAGCACAACCCACGGAGGGCACCGTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCGCTGTAGAGCTGAGAT
+
DDHCHGF@CBFGECEAAD@FHIDEHBFHDEAHCF@GEGHH8HHID?GIFHIBFHDFBAGCF?IDDGHAFEAAFDGEBCFADBEB>DHBGDD?C@D@I?A?
@>chr21:9646367-9646455-5
GCGGCGTACTGCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCNGAGAT
+
DDGFFH2B@?FEEBGGAC???A?A?@FD?ICHG?DE@E@@@?GFCHHI@IEADA?@AAGBEC?HEECGIDHHC@FFE@HACIIHABD?IFIDHH&@@CGF
@>chr21:9646367-9646455-0
TCAGACGGTAATCAGCTCTACAGAGGCATTGGCGGTGTTACAGTCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAG
+
DHEBGF?@IAGDAFAIDGAHAFEG)D?C@@CBCHCGCAE@CCE!@HC?ICFI??B?DFHDAC??@FCFGBA?GCBBGEH?@BDGCHEGFIGG?EBGICCH
@>chr21:9646367-9646455-1
TCAGACGGTAATCAGCTCTACGGAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAG
+
I@F@CAIGABGE?FHEHHHAAGDDACEEIAHF??CCCFCFCEEEBDEB?B?H?@H@AFDHGDID@IDGEAEDECGFIGE@IDAB@B@I@GHBDCHGGAAF
@>chr21:9646367-9646455-2
TCAGACGGTAATCAGCTCTACGGAGGCATTGGCGGTGTTACAGCCCTGCATCCACTCCGGCAGGGCAGGGTGCCCTCCGTGGGTTGTGCTCCCAGAGCAG
+
II??GC?BCFAEA?CIH?FDGAHA?CADF@BHADD@I3EEBBDHABI@FICAFF@GHHBEDDBIBCHECIEE@I?FBECDB@FIFGACBEABFE@H@F@G
@>chr21:9646367-9646455-3
TCAGACGGTAATCTGCTCTGGGAGCACAACCCACAGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGATGTAACACCGCCAATGCCTCCGTAGTGCTG
+
@CBCE?HACIFADDG@DIC?BGEGEG?AGGHFBG3CI@GH?CFDGID?FFH@@EDFG?CICG@I?AF@B(CAAFG@HH??ECDGIABAAIB@?FE8E@G@
@>chr21:9646367-9646455-4
TCAGACGGTAATCTGCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATCCCTCTGTAGAGCTG
+
IFBCIBEBI?BCDEDHDBH@@BA@BDHFF@H?C?@CB@A@CH@IDHFFEBHIIEHCIEFAAAHBH?F?EBDGEBHAIBEDBBIB@&@?HCAA@FA@FDGF
@>chr21:9646367-9646455-5
TCAGACGGTAATCTGCTCTGGGAGCACAACCCACGGAGGGCACCCTGCCCTGCCGGAGTGGATGCAGGGCTGTAACACCGCCAATGCCTCTGTAGAGCTG
+
AFGCHCBGG?BDEEIABFHIFBGAFBEFDFHCE?AGII?EIDICBED?EEIEGDDB@BA@BBFICGFHD?E@BEDBDGHDHBAB?HIDFEFI@?AACHHE
@>chr21:9656624-9656764-0
ACCACTATGTCTGCATAGTATTCCATGGTGTATATGTGCCATAATTTCTCAATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCTA
+
@CAECFGEFDBEGGBE?!GHGEH@ACBBIFECCD@DHIDHIDCHAFC@DDCE3HAD@C??EF@FFA@ICEDFAEAEDCGEFG?BBGAFHIDGEFHGBDAA
@>chr21:9656624-9656764-1
ACCACTATGTCTGCATAGTATTCCATGGTGTATATGTGCCATAATNTCTCAACCCAGTCTATCTTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCTA
+
CGEBF?FIE@E@?DGBHAG@HIDHAB@FGI@AFAEBBGDAIFIEB.CFIDBI!F@FCD@B?DH>FBEEG?DCDFCIHBF@AIEC?ACCA?BCDAAHCICB
@>chr21:9656624-9656764-2
ACCACTATGTCTGCATAGTATTCCATGGTGTATATGTGCCATAATTTCTCAATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGNCTTTGCTA
+
AG@@GE??HC?CHAIFBFD@CCCC@FC@?C@BC@CG@CDF@BE@GCBECH@AF?@BAHCAGFHFAIB@??AGBHF?@FBD@BBEIECEDF?5IFIIHCFH
@>chr21:9656624-9656764-3
ACCACTATGTCTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGGCTTGGAACCAACACAAATGTCCAACAACGAT
+
IAF@C?EECHEBH?GF?IDCD?HHADFG?@DAI?DBCGGHD@GHDG?DFDEFBHDDGCGAGGAEHE@G6A@GDC@B?FHI?GHCEH@F?BEAFEEIEEAA
@>chr21:9656624-9656764-4
ACCACTATGTCTGCTATAATCACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACGAT
+
:FEB@EABEAI?H@?@HF@!IE?@IBDGG@@CFBIECFGGCA@AA@FCIIEBH@D?CDDFHC?ECDGADG?ED@EEGE?IGF?GDEIEAGFDAB@GFB@H
@>chr21:9656624-9656764-5
ACCACTATGTCTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAAAGTCCAACAACGAT
+
H?BFFGC@C??FCB2@EABGDHECCGIH@@D@IAFACGF?B@BH?@E?HHGCCHA@??FEFABIA?B?FGDFIGBHIAGBAFCADB0DIBD??CBBD?E?
@>chr21:9656624-9656764-0
CTCATACCACGCTGCATAGTATTCCATGGGGTATATGTGCCATAATTTCTCAATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCT
+
GEFCABDD?IEBAFEIIBFFC?D@D?BBC@FBB@BAGC@IDE??B?G?@@BHFCACHH@IECHF@?F?DEFCF?@?AIEF@@ADGIF@DGEB@CFBAEBG
@>chr21:9656624-9656764-1
CTCATACCACGCTGCATAGTATTCCATGGTGTATATGTGCCATAATTTCTCAATCCAGGCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCT
+
IHE@IGBEBHIFGB@@CGDBIGA8??AGE@FECADGEC@EHGAFFH@DIHABIFFEBG$IFEHGHE?@H@@CCDGICDA@EFGCAIAFHDFDG3AGCID@
@>chr21:9656624-9656764-2
CTCATACCACGCTGCATAGTATTCCATGGTGTATATGTGCCATAATTTCTAAATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCT
+
BIC?@H@GAB?HG??DHE@EF@@CFGDDEB@ACHABHA?GDGAIFIEEEG>IDHBED?D?D@@BIEA@FFIDB?FGECE@AHF?IB?CH?DB?@IHGFDI
@>chr21:9656624-9656764-3
CTCATACCACGCTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCATAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACGA
+
GADC??CADDDECHDEHEHH@HGCABFCAHFG?FBFECHGCD???GBDGDIBBAFDB?)IB>DBD?CF?GFAE?GBGCCCEI@BFCGEFHEAICE@I@AA
@>chr21:9656624-9656764-4
CTCATACCACGCTGCTATAANCACACATGCANATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAAGGTCCAANAACGG
+
A?GCFG?EE@FFFH?FDHGA,HHEEDDGDF@>?@DGIGFE@@??DDIBCADGDEHBBICCBAEAIBGIDH@CCCE@EGA??HBBCCF7CEHEGC'EGFD.
@>chr21:9656624-9656764-5
CTCATACCACACTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACGA
+
CCBA@DDCI?#BHAFEEDD@II??ACI@C2EE@EIECI?A?BDCBC@FF?B?A@FAD?DFEIFII@IHAHI??D?FGCGFGB?CCHDHADI?BCDI?EI+
@>chr21:9656624-9656764-0
GAAGGTCCTCTGCATAGTATTCCATGGGGTATATGTGCCATAATTTCTCAATCCAGTCTATGGTTGTTGGACATTTGTGGTGGTTCCAAGTGTTTGCTAT
+
FECHBEDIBEFFHGG@I@AIGHAFABBGFAI@B@HCDBCBIBBIIGC?@H?IFEFHBB?FC-FG?IIDC@@CGEECGFH'@?GI@??@DDF;BID?BC@?
@>chr21:9656624-9656764-1
GNAGGTCCTCTGCATAGTATTCCATGGTCTATATGTGCCATAATTTCTCAATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCTAT
+
E:E@CC@IACF@BBEBABGDGEHHCGIE2@?DHHHAFACI@3CHAE@HDHDDG?BHIFGA@B@IF?FG@G@A@FCGFE?B?H@GEFFCFDDDEFFB?IBH
@>chr21:9656624-9656764-2
GAAGGTCCTCTGCATAGTATTCCATGGTGTATATGTGCCATAATTTCTCNATCCAGTCTATCGTTGTTGGACATTTGTGTNGGTTCCAAGTCTTTGCTAT
+
DFFDHHFI2BAE?ED?FIGHDGBA%CEFEA@AGBGHAGH@EFC@AHIBI<D@CH?EE?BDBIB@AGDCC?AIDFGGGIAH.HHF@@GEHIAG?BD??GCE
@>chr21:9656624-9656764-3
GAAGGGCCTCTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAGTAGCAAAGANTTGGAACCAACACAAATGTCCAACAACGATA
+
DBIFB'?GHDGAFAI@HDGFHFFC@HHGD@G@DGFAF@@FHDGDBA@BFHF?DDICIB1G@AHC?A@C3IECICGCFCAABFCHCEE@ABGG?FHHHBCC
@>chr21:9656624-9656764-4
GAAGGTCCTCTGCTATAAACACTCATGCACATATATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACGATA
+
GBHFIBHBCII@??D?BH@G@E3?G@G?CECF6AA??ECGIAF?GBEABCHEGDEEHI?ACCHAEGIADAB@C@@BBF?HFHEBIADA?GBGID?@GICF
@>chr21:9656624-9656764-5
GAAGGTCCTCTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACAAAAATGTCCAACAACGATA
+
AEDF@CI?C.HEAD?BHDEF?DA?DDAAFEEGEFDGIFEGH@@BIFDGFIAGG@@<?A?GAC@CICCHEHC@@CF?CBII?:CHD??CDGIEECIG?AEH
@>chr21:9656624-9656764-0
GCGGCGTACTGCATAGTATTCTATGGTGTATATGTGCCATAATTTCTCAATCCAGTCTATCGTTGTTGGAGATTTGTGTTGGTTCCAAGTCTTTGCTATT
+
BHGC?ECEBGE?BGG@GFIDA.FC@CAFIG@EDFFEE?C?AHAED@GBECB@EIHDG?DGDHI??@IEEA<@?G?ABDDIBEAI@EB@EDHD?HBE@@?D
@>chr21:9656624-9656764-1
GCGGCGTACTGCAGAGTATTCCATGGTGTATAGGTGCCATAATTTCTCAATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCTATT
+
@D@IAFGCI@EAA6?@CF?FC@ACFI?DDCCB-@ICI??DGE?@H3F?@@IGF??H@GIIGBBCAI@+AFH@HC@GBA?EFAHDEEGBHB?HA?HDF@HA
@>chr21:9656624-9656764-2
GCGGCGTACTGCATAGTATTCCATGGTGTATATGTGCCATAATTTCTCGATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGCTATT
+
GB?DCED@GBHFAH?DGAH@ACAEBDDB@EBAIAHBI@IBEBABA?DB-HGF?I?CD@FBFAFEGFCAICBBBAC@?GIDDI@?ADG@?CFIGGIAAEB0
@>chr21:9656624-9656764-3
GCGGCGTACTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACGATAG
+
BCCCIFGBGHDBHFBBFABIDCEB?EH?GDICCDDADHHFAECCAGIGD@FIBA@DFAFFCDCDBHA@E?HGH?EBD?FCABDICEGGDGC@EACIIBCA
@>chr21:9656624-9656764-4
GCGGCGTACTGCTATAAACACACATGCACATGAATGTTTATTGCCGCACTATTCACAATAGCAAAGACATGGAACCAACACAAATGTCCAACAACGATAG
+
CHCHGDH@FBHBAFD@?CIEBADECHHCFFA@,CB?GFFCBAEB?B?CBEHADABHD?BFHE?@IHI?#B?@H?G?ED?GC@EAFH?HBBBH?FIFFD@H
@>chr21:9656624-9656764-5
GCGGCGTACTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCTACACAAATGTCCAACAACGATAG
+
DDCEI?AEBEEBFDFDHA?IAF@?@FEDGDGDFDDFICADFBAGEDICHGA@HDGDABAHCBBEBHA@A?DFDFFE3@HB@IGEAACED?@IGABA?FEF
@>chr21:9656624-9656764-0
TCAGACGGTAATCTGCATAGTATTCCATGGTGTATATGTGCCATAATGTCTCAATCCAGTCTATGGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGC
+
FE@IAABAI@@FDFHBGEB@FDDEE@IGABE@???@DHHCDF@EGGA<IFB@HBBF@BEEDBD@;FFFIHDF?G?B?BEDG@GA@HHFC?FBEHIC?III
@>chr21:9656624-9656764-1
TCAGACGGTANTCTGCATAGTATTCCATGGTGTATATGTGCCATAATTTCTCAATCCAGTCTATCGTTGCTGGACATTTGTGTTGGTTCCAAGTCTTTGC
+
HBCGFDD@EC5IEG@C?GCEBFAF?DGDHF?BIHEID?F?ECB@C@IDFEG?EAEFGBEDFDIACBD@D,??G@GEFGAHGAID@CD?IIHBEACD@GAD
@>chr21:9656624-9656764-2
TCAGACGGTAATCTGCATAGTATTCCATGGTGTATATGTTCCATAATTTCTCAATCCAGTCTATCGTTGTTGGACATTTGTGTTGGTTCCAAGTCTTTGC
+
HBIDHE@FDHADGCIBFDC?FHAI@F?EBCGDBID@?@G.@CGDHHEFIG?CG?EAF?GB@AG?D??DGEDGFIFHAGD@@I@BHGGAFGAAD?G?HGGC
@>chr21:9656624-9656764-3
TCAGACGGTAATCTGCTATAAACACNCATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACG
+
EEIAFDEDFIHID@BBD?@BGHDHG$FF@EADCEFAF@HAIBAFHBDI?C?GDGGEFBCECB@II@FAFFC?HHIAIBCHBGG@FHCHBG@FADEAH@CF
@>chr21:9656624-9656764-4
TCAGACGGTAATCTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACG
+
CFG@IGDHGB@DACCFG?DCAH@ADHDCC?CH?DBDFC?GA@EID?DBIHIC?E@F@IFBABCAGCGFA@AE@DF?@IEFECFHFCGADHAADAF@DDGF
@>chr21:9656624-9656764-5
TCAGACGGTAATCTGCTATAAACACACATGCACATGTATGTTTATTGCCGCACTATTCACAATAGCAAAGACTTGGAACCAACACAAATGTCCAACAACG
+
@HDHB?GCFEGCBDFCII@E?GGI?ADD?B@GGHBHHBBFBEGBHDDAFBBCIGICABC@@?GDIC?@ID?BBCEDDEA@IGI2IHEC@HAICBC@?ACA
@>chr21:9656761-9656935-0
ACCACNATGTCTGCATNATTTATAGTCCTTTGGTTATACACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCGC
+
IFD@E8HAEHH,?FHD7BDA@DIBDEFBFEBFGICC@B6AIGFAGHACD@GICIIH@BBEFA?AF?IGDGCE@HHEGFDHDDEDEHHFD@IAHE?FGCFF
@>chr21:9656761-9656935-1
ACCACTATGTCAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCGC
+
AGCAIF@ICFE@IAI?D?BHBIF@CAA@BEEAHGC??BEICIIEGAEIAF@EBB@?AH@C?CIABC@BHEI?ADGDDFHFGGFHBIHCC@IAEHFDBBGF
@>chr21:9656761-9656935-2
ACCACTATGTCAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCGC
+
?H?FHHD?HDDIIH?@??EAAFDF@EIBBFFEFHFDGADHHBI@AGI@EDGIBHEACFIHCEBD?ICHBECFGDG?D@AAIAHAHIFGADGEFBBB@EC@
@>chr21:9656761-9656935-3
ACCACTATGTCTGCAGAGGATGTGGAAAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGTGGCGATT
+
B?BHIHDBDD??CF@@EEEEHGFBGD,GI@IGCCGIBIBGEBGDBECBIH?@G@GEH@@?BEFHEBCF?ABG?IGC@FHH@D@HDG@GCCCAI?ECBEFH
@>chr21:9656761-9656935-4
ACCACTATGTCTGCAGAGGATGTGGAGAAATAGAAACACTTTTAAACTGTTGTTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTGAGTGTGGCGATT
+
DI?BEGDADCGFDGB?GCFE?DB?FE@CEGE?IBECECFFG@EII?BDE@CA2GCCDEGI@GFEDHGEFHCD?F?G?@DHCF@CCIA<AGCB@CGFDDID
@>chr21:9656761-9656935-5
ACCACTATGTCTGCAGAGGATGTCCAGAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGGGGCGTTT
+
D??H?GFEDB@CEG@?G?BEIFF#-CAFA@@?DEFC?HD@EFEGBE@@?@FGBEIHEBFHFHE+GGI?IAFIH?H@?GIGAB@AHH?EHCBH,@CDF1HE
@>chr21:9656761-9656935-0
CTCATACCACGCAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCG
+
EGFHFFF?IB@B@GACGIEB?DDDDGDCG?E@E@DFIDCDI@FGHA@HHHFGHIFH?CEDBBHC?A?H?DCD6DHGICGCAI?A@HCCDIB@IEF@IIII
@>chr21:9656761-9656935-1
CTCATACCATGCAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATGGGATGGNTGGAGCAAANGGTATTTCTAGTTCCAGATACTTGAGGAATCG
+
EEEI?G?D?#DI?HFIBIGIB?FDFEIFDH@?HCDADAAFBB@FCH?CH@DCBFECE1HGGD%BGH<-EE?@IGIDEHGC?AEDFEED?@?HBGD?DF@H
@>chr21:9656761-9656935-2
CTCATACCCCGCAGCATGATTTATAGTCCATTGGTTATATACCCACTAATGGGATGGCTGGTTCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCG
+
GDECHE@B*FGA@CFHIEA@BIHIFCFBG9CIHDCG@CCGD?IGFHFAAIICI@HAIDDE@!IDEC@C@G?@CHDIF@@I?DI@B@GDFHGDFF?BDCH+
@>chr21:9656761-9656935-3
CTCATACCACGCTGCAGAGGCTGTGGAAAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGTGNCGAT
+
GBGIHED?IBFI?HDG@AAD.GCGFE?CH?AAABEBG???BCH@H@FAC@EGHHE?IDGFFD?@B?I@IED@HB@EFABFB?AFABCFAICIIAH.IDA?
@>chr21:9656761-9656935-4
CTCATACCACGCTGCAGAGGATGTGGAAAAATAGAAACACTTTTAAACTGTTGGTGGGACNGCCAACTAGTTCAACGATTGTGGAAGTCAGTGTGGCGAT
+
I@EFHGEAAI@A@BCFH?CIAEG??@ABDBCHDB?E@ICEFF??HBHIE@HDCFFE@??A0FG8CIEG@C??CH*BDH?G?E@CI@ADFIFHF@EDDEFG
@>chr21:9656761-9656935-5
CTCATACCACGCTGCAGAGGATGTGGAAAAATATAAACACTTTTAAACTGTTGGTGGGACTGCAAACNAGTTCAACGATTGTGGAAGTCAGTGTGGCGAT
+
?DICA?HBFF?FH@BABHB?@@C?GGBIFFEA?<CH@BBBGG?F?E0HEIA@FDD@CDC@CHBCDFE#E?BBCEGC@EFIGBHDB@IABD@IFEIEAAB@
@>chr21:9656761-9656935-0
GAAGTTCCTCAGCATGATTTATAGTCCTTTGGTTATATACCCACNAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGATTCGCC
+
CHIG/?GFG?@HGFAF@DGFBF?HDF?FFDAFGHIBHFFAG@GH4?B?C?GHCE?ADI@HIHACICI?F?ACFBEHEDAIAB?HHIIIIDIHEB#GI@HI
@>chr21:9656761-9656935-1
GAAGGTCCTCTGCATGATTTATAGTTCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCGCC
+
FFBFEHAE?E!CFBCIEH@@FBAFG#FCGB?GB@H?I:EHHD?C?GIBG?IE?GCGACDC@GHABEFI?G?IE?E@DHBCIADEDD?I?HC?HF@G?FBB
@>chr21:9656761-9656935-2
GAAGGTCCTCAGCATGATTTATAGACCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCGCC
+
IEED?@AFDGFDCDFEDGIB@ABE)A@G?EE?GBCAFEDIE@CAICFGCHDDDBFAIHFAD@HFHDABIEAEIEI?4?EEGGF?@DAAICEBDA??@FCF
@>chr21:9656761-9656935-3
GAAGGGCNTCTGCAGAGGATGTGGAGAAATAGAAACACTTTTAAACTGTTGGTGGGACCGCAAACTAGTTCAACGATTGTNGAAGTCAGTGTGGCGATTC
+
?FG?A$?7AFAH@FFBD@FCFCIF@BA@DDEB@?CE?IGFI?IDBAHCFI(DCC@FED6BIHDFIIDI@EGHIFBHF@CE(EGCEAFCBG@FEFGBIHI?
@>chr21:9656761-9656935-4
GAAGGTCCTCTGCAGAGGATGTGGAAAAATAGAAACACTTTTAAACTGGTGGTGGGACTGCAAACTANTTCAACGATTGTGGAAGTCAGTGTGGCGATTC
+
?FD?HGDCDIEBABAFECHCFCHGFGB?BIIC@FAGICAEBF@HAGDF.FB?FFBIFAF@IHHB@EF<IBBH?DFABDHGHBCFF@?@AG?BDDAIIGBH
@>chr21:9656761-9656935-5
GAAGGTCCTCTGCAGAGGCTGTGGAAAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGTGGCGATTC
+
@AAHI?IHGD@EI?BGBD<DDGAFIGDHCAHAH?GIIBDHGAIGCAIAFD@AHGFAEEFIABGHCCHCCIGB@!EAIGBFDE?HCH@AGBCF?IEBHEGI
@>chr21:9656761-9656935-0
GCGGCGTACAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATCGCCA
+
H?DEAI@DDBHE@DGCIG@G@A@GBCGCIIH?@CHGA@ADCDB@HA?F@AGHGBDFGIIGC@H@EFBIGHBAHAHIGABHHEEHEGFBHBC@IAGAD?HI
@>chr21:9656761-9656935-1
GCGGCGTACAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTCGAGGAATCGCCA
+
FFAHDAIBAAB??A?FCBCCBEF@ICCECD@?FFCC@IEHIADAHGFFIDCIGEG@EEECICC@DBI?@FIAGII@AFF?GEHAEIB!IABDBAFCDCHH
@>chr21:9656761-9656935-2
GCGGCGTCCAGCATGATTTATAGTCCTTTGNTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCCGATACTTGAGGAATCGCCA
+
DDFDBGE8D?HBIDBFHA@FGEI@?II@CF.?DC?FAIHFGD@AFBDCDCCHAFGGAHEED@BFBABFFEGEHHIEDCGB=HGBDFIA@IC@D@GA@A@@
@>chr21:9656761-9656935-3
GCGGCGTACTGCAGAGGATGTGGAGAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCGACGATTGTGGAAGTCAGTGTGGCGATTCC
+
?GF?A@@IIFDFCHBDB?C?DGEC@GCIBIHBCHIBDFBCDFE@CDCBB?DCG@H?FAGC?DABDDHABD$@E@AFBHF@?HFAIEHDGGH??ACE@IDA
@>chr21:9656761-9656935-4
GCGGCGTANTGCAGAGGATGTGGAGAAATAGAAACACTTTTAAACTCTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGTGGCGATTCC
+
EFA@@FCC-F@CDFAHHFDCEHEBFIE@EBFDBDGGAF@EE??EG?<IAIC?E@HC@@@@GHFED@@IF@I?FADIF@IAFFHF@@?GADAADD?HFCAA
@>chr21:9656761-9656935-5
GCGGCGTGCTGCAGAGGATGTGGAGAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGTGGCGATTCN
+
IDI?@@@-CHHFG@FAIG@FIDCICGIAHFDBFD/CGFBHBHDD@EDA@B!?GAIIIIAB@GEGGFFG?HC@B??@GA@HDFGIFBHG?HFBC?FDD@H=
@>chr21:9656761-9656935-0
TCAGACGGTAATCAGCATGATTTATAGTCCTTTAGATATATACCCACNAATGGGATGGCTGGATCCAATGGTATTTCTAGTTCCAGATACTTGAGGAATC
+
HICAIGBIBDBIEHECGHGAD@ADHEBID?GB@1B$HDFHDIHFGHH1FEFEB?DF?CFHD@FGG<DBDHC@DDAIB?ICFADDFCGFCHAGHEHA?AAG
@>chr21:9656761-9656935-1
TCAGACGGTAATCAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATNGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATC
+
IHFH@CC@G?GFAHCFA@CG?DHBB??FFBAHDFGGAAE?EFFA@ICGF?@0?D@?GAGF@E?@G@A@@?@IABBIHAEEGGAHGGI?EHEF?ADDCBHD
@>chr21:9656761-9656935-2
TCAGACGGTAATCAGCATGATTTATAGTCCTTTGGTTATATACCCACTAATGGGATGGCTGGATCAAATGGTATTTCTAGTTCCAGATACTTGAGGAATC
+
CEE?BADABAHFDAGI@BIIA@IB?EDFFBHHAFBFGHA?@FBF?AGEBFG@B@ED@AAGAH?BIEC@GEEHBCBAFCADDHEAI@@A*C@CIBD?DCHH
@>chr21:9656761-9656935-3
TCAGACGGTAATCTGCAGAGGATGTGGAAAAATAGAAACACGTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGTGGCGA
+
BEBIB@FHBGC?@I?BIE?CBGCA?CEIEI?@CEGH@DIFH=DG@IA@DGCF?GIDHG@IHIGFHFBHCBHBCBDIHIH?AIICAG?@BF@GIGB?BABB
@>chr21:9656761-9656935-4
TTAGACGGTAATCTGCAGAGGATGNGGAAAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTTAGTGTGGCGA
+
B;A?DBFGFICDCGBFFFHDE?BI&?@?HDGCGFAHCDAAE@GEI?C?AIGF@?D?GHIFA?GDFEFIGH@GIEGCGAD?ACIFGBAE@!GF@ICB?EFF
@>chr21:9656761-9656935-5
TCAGACGGTAATCTGCAGAGGATGTGGAAAAATAGAAACACTTTTAAACTGTTGGTGGGACTGCAAACTAGTTCAACGATTGTGGAAGTCAGTGTGGCGA
+
CD@?F@IC?GBFC8IGAGHABAHGDE?CADBE@HADGFDEFGIEHDCD@GHEB?DEABH@AA@C??IAIABFEI@IIBBIH@GAGCGBGHD@ICBH)G?I
@>chr21:9656932-9657065-0
ACCACTATGTCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGCATCTCATTGTGGTTTTGATTGGCATTTCTATG
+
GE?CEACI@FHBC?HD@C?CF?IDBFAIGGA?IC?FGECCDGDHC@?EFF@CBHH?FCFFEDGCECF:FBDIBEI?HDGFDCC@D?@B$FFEIE?CGGFB
@>chr21:9656932-9657065-1
ACCACTATGTCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTATG
+
H@DBBI@BHFAIFGG@IAIAIAGCHFDBCABA@F?IIHC?CEGC?D??@GHIGHHGE@AGGFDCEIEBFCAEFHCEAB?AH?A@ADD?ABHG?I??HCI@
@>chr21:9656932-9657065-2
ACCACTATGTCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTATG
+
FICD@G?DB?F?HFHD?FHDFBIII?@AACDCEIAEIABE@DFGGH@BEE@D@EHIDI?DIDBGAHHD@@HIC?CIAHF@A@CGEHIEC??E@@DFC@BA
@>chr21:9656932-9657065-3
ACCAACATGTCAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAAATGCAAATCAAAACCACAATGAGTTACCATCTCACACCAG
+
E?F?!7G?BIHCEDEGAAGDBCEBEIFBHI@E?HBB?I?EH?@?@@@EC??HIDACBC?FACHBC?GGH@HCFIFH@A?BFGH$EGACFCCD@A@@HDGD
@>chr21:9656932-9657065-4
ACCACTATGTGAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAAACGCAAATCAAAACCACAATGAGATACCATCTCACACCAG
+
8FAACCCFDCBCF@GEID@EIB?FICEEGHEGIFGDCIBB@?G@@?HCAFE3ACFGAHA@A1??BGHACIHF@?@?CFEAAIGECEADAIG@CEF@IGA@
@>chr21:9656932-9657065-5
ACCACTATGTGAGCCAAAAGACACATGAAAAAATGCTCATCTTCACTGGCCATCATAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCAG
+
CIGI@@HGCAICBBI@?A@DFACIFE?F?E?@EBDE@DEBD/HGCFFFEAAAHGFDCCGHHF@FE?D?CBFGGA@IHF@@@DHFBB@EH@BBHIHCDFDF
@>chr21:9656932-9657065-0
CTCATACCACGCAGCACCTGTGGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTAT
+
HFE?EFD@HHH?IIE@GEE@I3B?CEGC?@CHBDGCGHEFIIHDIAFH@CDFEEDBBGF@HH?FG@DAIFADB?DHFB@F?GAAEIAFFBGHEBFGDABG
@>chr21:9656932-9657065-1
CTCATACCACNCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTAT
+
ICBGE?F?E?4?BDDEIBDEC?C?A@HCEEC@CAA@?A?DG@??CBDHAACAIEGAI?D@@IIEB?HE?DE?HEGBHICGAF@?A@CH"HAEHF@EDGHC
@>chr21:9656932-9657065-2
CTCATACCACGCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCCTTGTGGTTTTGATTTGAATTTCTAT
+
?CBBAHDGDBBG@BGB@?CCI@AIEFDAGAH@BA?G?DEEEGH??A?FCE?HCIHAI@DCGIEI?@IH??GHDH+GGEGBAACACC?ADDI>CCFB@EEC
@>chr21:9656932-9657065-3
CTCATACCACGCAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCA
+
AB*@IGDAHIDA?@BCAGDFE?H@@BBHEIHICFAHE@IBFIIGHCGCEGF?B@HIDDHHICFGCBGI@F??HHI@?ABGFIAD@HCBCHGIHBGIGBF?
@>chr21:9656932-9657065-4
CTCATACCACGCAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGTCATCATAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCA
+
@FIGCI?AHBBE@H?F?FGGHC?EB?@HFDADBACEH@AGGAABABHF?D0ABCB?BHCBEF@HB?FB@CEI?IHIHFAHD?@CIHAFHFGGBFF?BBHE
@>chr21:9656932-9657065-5
CTCATACCACGCAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCA
+
D@BGHEF?EEADII?FDC@A@G??@EBI?DGHCBA?IICBGHCFFGHDI@ABEAH?FDCCBF@@DAGFAIBACBIH@BDEF@CCFG?IC?CCBHD?EFIE
@>chr21:9656932-9657065-0
GAAGGTCCTCAGCACCTGTTGTTTCCTGACTTTTTAATCATTGCGATTCTAGNTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTATGA
+
@GGEHCCIGDGBF?HGHFDIIHD@HH@EFBCD?ECHH@&@AFEHB@BEGB?:=@D???CBCIBC?DEDG@BC@GCHDDFE?ADAEBF@?HC@DHBIG?FC
@>chr21:9656932-9657065-1
GAAGGTCCTCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTATGA
+
F@FDG?@@@EEFICEA@FE@D?AAFA@IABEBI@@D?@DFG@IIID?DE?GHBFAFGH?IEGEG?IFDF@FIAIDDAAA@FH?IFDAAGBCDBFCAHGIA
@>chr21:9656932-9657065-2
GAAGGTCCTCAGTACCTGTTGTTTCCTGACTTTTTAATGATCGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTATGA
+
EHF@HEG@G@EI(ICBAEADC@@@FC??BCADHF?EEBA9B5IHGGAEAD@E?ABGHHHIG?FBAHD@BE@@@BFA?FEFGEBGGBAHHGCDBFFEBIHC
@>chr21:9656932-9657065-3
GAAGGTCCTCAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAAATGCAAACCAAAACCACAATGAGATACCATCTCACACCAGT
+
DBGF?I@??HIH?BEHGICBGAIADDGCD?EGFEHGIHBHIEGGFEFEBGG@?H?DAEGFI/?@DC%D@@C@AAI&ADIBHEGIHBB?@IDHA@EGB?AA
@>chr21:9656932-9657065-4
GNAGGTCCTCAGCCAAAAGACACATGAAAAAATGCTCATCNTCACTGGCCATGATGGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCAGT
+
A#EHF@BEA?DBEE@EIHEHHEEH??HG@4BIAADG@DII0FG@?H@EFBAC4IF#CBFFA@HBBCBDD@DDEHIFFBE?ACGFG?@G@HGDACAECFGI
@>chr21:9656932-9657065-5
GAAGGTCCTCAGCCAAAAGACACATGAAAAAATGCTCATCATCACCGGCCATCATAGCAATGCAAATCAAAACCACAATGAGATACCATCTCACANCAGT
+
BEGEDGFH?BAGEAC?BEDEH@IFEBH?B@?A?HFFFIA@ECFFC%EBEBICBBGCH7?IBDHHFGD?FIGECH@BFIAFADGE@ECIB??GFC?;?C@D
@>chr21:9656932-9657065-0
GCGGCGCACAGCACCTGTTGTTTCCTGACTNTTTAATGATTGCGATTCTAACTGGTGTGAGNTGGTAGCTCATTGTGGTTTTGATTTGCATTTCTATGAT
+
?@?@B?5E@IBBGHAFAADI@@HFDA@IB?;BFCCCBGCGDGEB??IA?BDI?EG??EEBB:ECAEH+CADBGH@GCBIIEAD?A@B@DIDFE?AB?F?H
@>chr21:9656932-9657065-1
GCGGCGTACAGCACCTGTTGTTTCCAGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGATATCTCATTGTGGTTTTGATTTGCATTTCTATGAT
+
CIEAFFF?AABBFDBB?EIDBAFHC.BHFDID@BDG@@@HCA)BGBE??DH???B?@CBBIBIA!IEIAEHEBIGIEGECIBIGF?F@CICAC?EF@@AB
@>chr21:9656932-9657065-2
GCGGCGTACAACACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTATGAT
+
DDDBEFA@EH9DACAD@GHFCFBHEBHHE@BBBGIIIGI@A?B@@GGI?AFDACDHB?IIADAGBC@C?EDGICI@CECAHDAAF@C??IF???BFC@GH
@>chr21:9656932-9657065-3
GCGGCGTACAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAAATGCAAATCAAAACCACAATGAGATACCATTTCACACCAGTT
+
@II@BDHGGIGICGDAECCFI?EHC@GIEF?DFF?@CI@B?AAABE?ECDFIHE?ACI?CDGA@HE@GBBGCCGCIGB@D@CBIGA?I,C@DG@IG@HI@
@>chr21:9656932-9657065-4
GCGGCGTACAGCCAAAAGACACATGAAAAATTGCTCATCATCACTGGCCATCATAGAAATGCAAATAAAAACCACAATGAGATACCATCTCACACCAGTT
+
CA?IEIICF@I?CCBH?IBDEF??BADFHI7?DGIC?B@FCEAEGDIE@H@H?BEIG@@BG@GCG@6IG?BGCDHB@GICGCIHFF(ECAED@HGGC?EE
@>chr21:9656932-9657065-5
GCGGCGTACAGCCAAAAGACACATGAAAAAATGCTCATCAACACTGGCCATCATAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACCAGTT
+
BHCGBFFDEI@IGGEA?DB??CAGEEEFA@HADEA@C?AH,BD?@CGIDGAICH@C?G@FC@A?FHIEEBFDG?IGEEIAC?CHGECAAIHIIBGC??DB
@>chr21:9656932-9657065-0
TCAGACGGTAATCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGGTTTTGATTTGCATTTCTA
+
AEEABBAED?CHDIFBICBC@@@FFCIFDG@?DABDEGB@BH@HDGHHGHHBE?HEFFHHFDEACDGEFFBBAF??IA@?AFCDHIGGE?IDAHAGCAA?
@>chr21:9656932-9657065-1
TCAGACGGTAATCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTTTGGTTTTGATTTGCATTTCTA
+
HHEHABAFDD@FAICE@CA?@I?EIBFE?@GBH@GBDHHCEG@CGFIF@@ECBE@?AB@H@I@DEGDDDEIGDFBCC@3??D8AEBH@FIFC@@CBFEEH
@>chr21:9656932-9657065-2
TCAGACGGTAATCAGCACCTGTTGTTTCCTGTCTTTTTAATGATTGCGATTCTAACTGGTGTGAGATGGTATCTCATTGTGCTTTTGATTTGCATTTCTA
+
@ABD?CF@IIIEGFHEHDBBDCHD@FCGGAF$EID?AAI?DGD@DBHB@FAFGA@IGHIBICI@CICFG$EAFBFIEAFC@9BGIBCGGBGC?EBEGIDG
@>chr21:9656932-9657065-3
TCAGACGGTAATGAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAACTGCAAATCAAAAACACAATCAGATACCATCTCACACC
+
GCDAGD@B?IFCH@?AGABDE?%HF?@EHICDE@GAI@BA?DE@HC@CH?@@G@IFHH?@H?&@HHIBIDFIDAF'DAG?HC$HDDECB@G?D@EIF@DF
@>chr21:9656932-9657065-4
TCAGACGGTAATGAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGCCATCATAGAAATGCAAATCAAAACCACAATGAGATACCATCTCACACC
+
CHDCBBBEFFHGCBA@I@AAEGFIABGI@?DBIDFDCGAEAIIBC?D?@BB?G@AABAAIIAHCGAEBB?EDBIIEICDGCCDE?EBGEBHDFHGEB@?B
@>chr21:9656932-9657065-5
TCAGACGGTAATGAGCCAAAAGACACATGAAAAAATGCTCATCATCACTGGTCATCATAGAAATGCAAATCAAAACCACTATGAGATACCATCTCACACC
+
GGCBGBHFECEBFGCGDDEHC?ACB?@GDF?DDE?IFGGHFIIECE?BBC@:DCFCB?@AHGGGHGEBIGAIBBEAI?I#H?AEGDI@?FBADFFIDFHI
@>chr21:9661606-9661707-0
ACCACTATGTCTGCTGTATGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTNTCAGTGTGCCCCTACTGGGGGGCGCCTCC
+
AAHEHBD@FGIHCEAED!I?DDGFCDFBEDIHA@CC@GFDGEDADBFHGIEFIBB@ECDGEDGCBA?BFI+EBH@EHDDE?A?BIEI?AHB@FDD??BDI
@>chr21:9661606-9661707-1
ACTACTATGTCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGCCCCTATTGGGGGGCGCCTCC
+
HB/HEGFEFBCHGDBI?DAFIIHDHAFB?@DACI@F@E@@ID@@BEA@F@FDGFD?EDDD@BFHCABECCHA@?GGBH??CD?IF"F@CDFII@??@EHF
@>chr21:9661606-9661707-2
ACCACTATGTCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGANTGTGTGAGGTGTCAGTGTGCCCCTACTGGGGGGCGCCTCC
+
ICIHD?ECECIA@DB?GGAHE?2HCCFHCABIGHIBD?CEGFEHDHCAFEBADGADIH&4BAB@GFECCEEFGAEC?I@CGIDB@HB@EGBDFBEDHG?E
@>chr21:9661606-9661707-3
ACCACTATGTCAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCACACTGACACCTCACACAACCGGGTACTCCTCTGAGACAAAAATTCCAGAGGAACGA
+
@HIIAEHIAGFGGCDFAAAHB@DEDEI?H?F@E?ICCAIGIFIEEH?FBCIEEBDH??EIGEB?IC?C?D@?EFGFGHCHGDCCFDBABBFBBAFDFFDE
@>chr21:9661606-9661707-4
ACCACTATGTCAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCACACTGACACCTCACACAACCGGGTACTCCTCTGAGACAAAAATTCCAGACGAACGA
+
BDA@?I@FIB@CGE@G@HIG@?IICAEAEHFEE@EA@IEAG@G?CGHB???GIBIAC@HFFHC!AE@?FCFB(?ICEBIEHG@E?@?IEAFH@#AFDFH@
@>chr21:9661606-9661707-5
ACCACTATGTCAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCACCCTGACCCCTCACACAAACGGGTACTCCTCTGAGACAAAAATTCCAGAGGAACGA
+
CHAEAAA?IH@E?EI??FADHCEAFIFFIBF??BFCGEH@DAICD5BDG?B#C@DH?G?DBB-@AG?@BDHFEEDGBIFFCIAEFIDGAEDHEEIDGICE
@>chr21:9661606-9661707-0
CTCATACCACGCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTGGTGTGAGGTGTCNGTCTGCCCCTACTGGGGGGCGCCTC
+
IG@HFFAG@I@FBFGFDIBFAFBA@EF?CID@BFCA@?AC@@HGAGGHA?E?AGH?H@FIE5HHFI?H?HHBFA;EEC@BDG?IGBHA@GD?BGBGI?DI
@>chr21:9661606-9661707-1
CTCATACCACGCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTCTTCCCCTACAGGGGGGCGCCTC
+
DFEBEDBICCH??GHDGF(FHG@F?HG@I@ICGA?CBIAI@IE@GE@HFFCEDAGE@IAIGFEHAAHE@?CGC?GHDII$D@?F@GH9D?CCAGEEGGD?
@>chr21:9661606-9661707-2
CTCATACCACGCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTCTGCCCCTACTGGGGGGCGCCTC
+
GBBEGADFEEABIFIIFFEHGBEGBDI@EEACFF@?ABIHDIIHBEGB?GHDEDBD?HDA?BHCBCADAFFHB?EAIID@AG1CFDFE?EFAFDBFCBFD
@>chr21:9661606-9661707-3
CTCATACCACGCAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCAGACTGACACCTCACACAACCGGGTACTCCGCTGAGACAAAAATTCCAGAGGAACG
+
IF@AGIFGIGEI?BBGHHHDF?DIHE?D@EE@DEICDBAHDEDA?CBBDDIEF?CGCFBIB?HF@@@HCD?AHD;?I@CCIEC@A?BBCEADA?GCDFGI
@>chr21:9661606-9661707-4
CTCATACCACGCAGCCTAATTGGTAGGCGCCCCCCAGTAGGGGCAGACTGACACCTCACACAACCGGGTACTCCTCTGAGACAAAAATTCCAGAGGGACG
+
CDFC@FI@HA@AHEH@?FHIAGF6AG@@BEBBCEDBHI?@@A???FB??D@CA@HEE???GCHIAHFEF?AIA@IIB?AFAICDHFGABICGCGEI%G?F
@>chr21:9661606-9661707-5
CTCATACCACGCAGCCTAATTGGGAGGGGCCCCCCAGTAGGGGCAGACTGACACCTCACANAACCGGGTACTCCTCTGAGACAAAAATTCCAGAGGAACG
+
EB@C?@AA?HG?I@IGGCFHEIIHB?D4BEGGGHBDI?BEGEGC?HBEBID@@DGE?H??$B?BHHDDB?BCE@CAHFCFDDCHBGHDHHI@DDIGAD?G
@>chr21:9661606-9661707-0
GAAGGTCCTCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGCCCCTACTGGGGGGCGCCTCCC
+
DA@EF/GEBCBFIBGC?DE?GCDD@@CCGADB@@AE?DGFGAACGHDA@C?I?@I@GDHCCIEDHDG@I??ADBDBDCDCDG@CCBEBIHCBFBD?CE@H
@>chr21:9661606-9661707-1
GAANGTCCTCTGCTGTCAGATCGTTCCTCTGGATTTTTTGTCTCANAGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGCCCCTACTGGGGGGCGCCTCCC
+
B@C:FIGDIIF@DICAC>A@GEECBDIDC?GEG%?AAEHEEH@BD*CGGHAEDCDGHIBCDCEFEEDIBFACGA@I@IF0CB@GH@?E@BH@HABD?CEI
@>chr21:9661606-9661707-2
GAAGGTCCTCGGCTGTCTGATCATTCCTCTGGATTTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGCCCCTACTGGGGGGCGCCTCCC
+
GC?DACCBHE5FBCDBGIGAAA5@GGD@AECIC%G@@I?IEHB?H?BGDEF@B@?HCD?DDCCEIAHDFD?H@@BEIDE?@@AAED,EBFF@CCBG@BHH
@>chr21:9661606-9661707-3
GAAGGTCCTCAGCCTAATTGGGAGGCGCCCCCCAGTAGAGGCACACTGACACCTCACACAACCGGGTACTCATCTGAGACAAAAATACCAGAGGAACGAT
+
HEIGEIACBBFIHDCGII?I@DHCBBBBBDBDAIIEHH:G@CI??BF@AFFD?CBGB?GI@@EIFDD@C?I,CB@@IIEA@?CICB3@ADFIE@GEEG@@
@>chr21:9661606-9661707-4
GAAGGTCCTTAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCACATTGACACCTCACACAACCGGGTACTCCTCTGAGACAAAAATTCCAGAGGAACGAT
+
EF@CEF?HB;E@CAEBA?AD?AC@EGFHIADG@BID@GIAEG@?D4A?BIHGFEBB@BCEHFEHFF@CGA?@CFEGA?AEBGH?E@H?@@??F@@HHCDC
@>chr21:9661606-9661707-5
GAAGCTCCTCAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCACACTGACACCTCACACAACCGGGTACTCCTCTGAGACAAAAATTCCAAAGGAACGAT
+
?G@F!GEFC@FG@ID?HECH(EFEEEBHCDC@ACFEH@?HF?HGFH@?CIEEDA@IBGCB?DA?ADIBDFB@CAIGBHBIGDGHHGIEI?)CAICEIFDG
@>chr21:9661606-9661707-0
GCGGCGTACTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTGCGCCGCTACTGGGGGGCGCCTCCCA
+
CDFEAEFBGA??BGB?EDCDGD?HAICAAAFAICDDFG?FA?FB@@F?EIE?IDAGECBD?C@CDGI@IDEF+HC4@GD%ECDBAEAHDB?GGIH?AFAA
@>chr21:9661606-9661707-1
GCGGCGTACTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGCCCCTACTGGGGGGCGCCTCCCA
+
BFB?CDAI@CFFBHA?@HGBAAFCEEEHAFDAGC@IIIGBDDHCD?FCG?HA?IFFADCHC@D?DEDGEG?@@BDBF?GAA??G@HAAEDIH@EBGAEDH
@>chr21:9661606-9661707-2
GCGGCGTACTGCTGTCTCATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGNCCCTACTGGGGGGCGCCTCCCA
+
EBDFGCCB@EIE?GIDI'B-@DHEDF?BGGD?GIBCH?GGIFAFIBHDIIDADGBFG@CEFCD@CEEFBBA4BCA?F6EEEEAC?FA?CGC?EIHDDAG?
@>chr21:9661606-9661707-3
GCGGCGTACNGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCACACTGACACCTCACACAACCGGGTACTCCTCTGAGACAAAAATTTCAGAGGAACGATC
+
IGBFDC@EG-AIA?HE@DFDGAGGHCBG?BIBGFGEBCH?IDFACABCFCCF?DBIHG@@GAIEHHGCD@GIDDFEGIEAAG?AAB2HHHIBFIGBECB@
@>chr21:9661606-9661707-4
GCGGCGTACAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCATACTGNCACCTCACACAACCGGGTACTCCTCAGAGACAAAAATTCCAGAGGAACGATC
+
E?D?@BFDIB@BBI6ADADDEGEHEAI?@GFIHECBEFHBFB>@IAC.GHIE?AFA?DD@BFA@CCBCH@BH@>IDBI?CD?D,IDBD@ACHFIBAIBAF
@>chr21:9661606-9661707-5
GCGNCGTACAGCNTAATTGGGAGGCGCCCCCCAGTAGGGGCACACTGACACCCCACACAACCTGGTACTCCTCTGAGACAAAAATTCAAGAGGAACGATC
+
FCC8AF@E??F59E?BIICA?@G?IC.CFEGBAG@G@DFGAEEFBFHGDDIC$G?G@FGFIC<G@IA@E?@AHEF??H@@EHEGC@B;BDCEF2HI?CDC
@>chr21:9661606-9661707-0
TCAGACGGTAATCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGCCCCTACTGGGGGGCGCCT
+
??C@?I@BFGCFICG?BEAIH@DGBGFDDIBBDGFHE@EB?BHDC@I?F@EEGIFECE.@DCEFGECB@??CIACBECEHIAF@CEIGDGEDFFCI?C@F
@>chr21:9661606-9661707-1
TCAGACGGTAATCTGCTGTCTGATCGTTCCTCTGGAATTTTTGTCTCAGAGGAGTACCCGGTTGCGTGAGGCGTCAGTGTGCCCCTACTGGGGGTCGCCT
+
C@@ABBBEFHAHICIECGBIHACI@GCDCA@B@BCGECIIFADFEGBHBF?G@GCGC4?IFHFG(C@FGHD,IDFFC?FC@HI?BE?CECBG?B=*HBBI
@>chr21:9661606-9661707-2
TCAGACGGTAATCTGCTCTCTGATCGTTCCTCTGGAATTTTAGTCTCAGTGGAGTACCCGGTTGTGTGAGGTGTCAGTGTGCCCCTACTGGGGGGCGCCT
+
HGIFI?B?BHEEHHCFA0?AEGHAHCBFFCHGGAD@HGFAG!FI?GHHI3EBFCF?5ABG?FF?HGBHDIBIFAHIAC@@CBIDGCIDFDGCAAHFBDGC
@>chr21:9661606-9661707-3
TCCGACGGTAATCAGCCTAATTGGGAGGCGCCCCCCAGTAGGGGCACACTGACACCTCACACAACCGGGTAATCCCCTGAGACAAAAATTCCAGAGGAAC
+
II0CFBHDIDEC@CEHCE?DCED?@?G@HIFBABDDACH?HGBHIEBGDIBIDCHGGBAIAHE?I@ACFC@4ABH'@B@ECA?IIABCGG@CGCGC?G@@
@>chr21:9661606-9661707-4
TCAGACGGTAATCAGCCTAATTGGGCGCCGCCCCCCAGTAGGGGCACACTGACACCTCACACAACCGGGTACTCCTCTGCGACAAAAATTCCAGAGGAAC
+
A?HIHDH@G?BADIFEGFGC?GEGC/A/DAG?CIID@DC?FH?HDAD?AGH?GBGFEB?FECF?BEDCBH?IHE@CACI;EDI?G?AAB?CHHDFEIED?
@>chr21:9661606-9661707-5
TCAGACGGTAATCAGCCCAATTGGGAGGCGCCCCCCAGTAGGCGCACACTGACACCTCACACAACCGGGTACTCCTCTGAGACAAAAATTCCAGAGGAAC
+
GA?CCEIGED@DIDECE6BHCCGCGAACHCBIDIICEAFBF?1BF?I?@ICCHIAAIAEB@AEE@IG???BAG@G@D?ACAGDCE?HFBDHFC?D$@AHD
@>chr21:9661704-9661771-0
ACCACTATGTCTGCTTGGAGGTCAGGATCAGGGACCCACTTGCGGAGGCAGTCTGCCGATTCTCAGATCTCCAGCTGAGATCGCAAGAGCGAAAAAAAAA
+
?HAC???DDGAHGDCFBF+B@CEH@I.D@EH@CHGE@FEEGH?F?GAGD?ABGBAGB)DGBEE@?GGCFCCG?HDH@HAHCE@6A@DB?BD?@HHA??G:
@>chr21:9661704-9661771-1
ACCACTATGTCTGCTTGGGGGTCAGGGTCAGGGACCCACTTGCGGAGGCCGTCTGCCCATTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
G@@I@@B@B?IH@BIAFBACCBAFGI@GECEECFGCD?HIEG?C@FAFI=?EBDAIG@FEFFFAGCHHC?CFAGC?DHBDAAG?BD?@?CBEDCCCH?II
@>chr21:9661704-9661771-2
ACCACTATGTCTGCTTGGGGGTCAGGGTCAGGGACCCACTTGCGGAGGCAGCCTGCCCACTCTCAGATCTCCAGCTGAGTTCGGAAGAGCGAAAAAAAAA
+
BEIAEDFDAHACC@HBEHB?HABACG?GCIHGABFDHGACI@BBIIIFCHB#I@H?EAD=@DCAGF@FDIBADAFIBH@7I@FCG??@BD@EICHEIDDD
@>chr21:9661704-9661771-3
ACCACTATGTCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCGCAAGTGGGTCCCCGACCCTGACCCCCAAGCAGAGATAGGAAGAGCGAAAAAAAAA
+
BHABCCF?AIE@@F?AE@DIHAG?DBC?DHBGIH?DEGC@CEIG?DEI@FIDAH@AA7CGC?IDHH?IDAGI?AID@D?DD5@@E?DGCDG@GAACFFIB
@>chr21:9661704-9661771-4
ACCACTATGTCAGCTGTAGATCTGAGAATGGCCAGACTGCCTCCGCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
F?AH@@FEACIAB?GI2IEABGAF?*?G?GB$F?EICIAG@@?C?B?EBBIDIBEGDDBBBEICCBBEICCAHG?@HGHB?@IEDFGAEBFCEIAC@GF@
@>chr21:9661704-9661771-5
ACCACTATGTCAGCTGGAGATCTGAGAGTGGGCAGACTGCTTCCGCAANTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
HG@EADFIHEB?IAF@??@G?CC?D@F5F?GGI4@E@>HD#CFB@?G?#HCDFD@DFH@GEBFIIE?HIGFD?E?IBHFF?GHBFCE@GCB4EEFCDEB?
@>chr21:9661704-9661771-0
CTCATACCACGCTGCTTGGGGGTCAGGGTCAGGGACCCACTTGCGGAGGCAGTCTGCCCATTCTCAGATCTCCAGCTGAGATCGGAAGANCGAAAAAAAA
+
?@H@BEIH?IAGF?BIDB?FIHC?ABGAFBH@GCHCHAD?CDAF?@AEDBBCFFC?HGDDCCFCBD?ICDIHIFCCIFE@@CIF?HEA@3B??ICDCADH
@>chr21:9661704-9661771-1
CTCATACCACGCTGCTTGGGGGCCAGGGTCAGGGACCCACTTGCGGATGCAGTCTGCCCATTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAC
+
@?BII?AGDACHDFIBDAGEGC<?ECFHABHDAF@GF@IGDGDAGCD=EBIEC?HDFIFFADAIIGECG@BFFBDGEBGHDEIIEAHFCD?GH?GCHCH+
@>chr21:9661704-9661771-2
CTCATGCCACGNTGCTTGGGGGTCAGGGTCAGGGACCCACTTGCGGAGGCAGTCTGCCCATTCTCAGATCTCCAGCTGANATCGGAAGAGCGAAAAAAAA
+
DFBE@!EHEDC1FGA@AEBECCAG?EIGC?AIGGEHC@EF?AADCDHFAFDC?ACECD@HHDABBCIBIFHIFIFHHIA+H?CGE@?@B?@F@HHCGEFB
@>chr21:9661704-9661771-3
CTCATACCACGCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCGCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAAA
+
GFDAE@B@H?CEI@CCGAFICEHGCACHH@??CAFHEACADHFGA@I@D@H?IEDBDIHBEG@F??FHI@CCIE@HFFEHCIIHE@AFIGBAFEFEABCD
@>chr21:9661704-9661771-4
CTCATACCACGCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCGCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAATAAAA
+
EICAGDHHCFAGGG?BCIHICB?ADCICFDBDFD@@AGGIICDDE?ICEA@HAIFB@CE@BDHFIG@ID@?G@?H?DIA?@IAAHBHBHIIBBA?<@EGC
@>chr21:9661704-9661771-5
CTCATACCACGCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCGCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAAA
+
AAF?HCFBF?A?ICFABDFICGEADFBBBH@FGD@GFE@GHCAHADEFCEHDDGAIFFFEIGEFFBEIEDAAI@CE@CAD8FH?@BBA@GGACECCGIDE
@>chr21:9661704-9661771-0
GAAGGTCCTCTGCTTGGNGGTCAGGGACAGGGACCCACTTGCGGAGGCAGTCTGCCCATTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
IHIIIDDBC?EH@H?ED6FGGHEFBD%CIF?FECFHGFFI@@FDG?GCG@HAEBBDHBIFFIBDBHEAD?G?D@ECIHEFECEIGCDDHDDACHH@HICD
@>chr21:9661704-9661771-1
GAAGGTCCTCTGCTTGGCGGTCAGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCCATTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
HBIAHDEEGCGHHGFIC8?BC@BGGI@I@IHGCFCHE?CIAFHFI@?FI@BHGHBHI@D?EBEBCGCE@GIHDGBHHII??@@??FCDCH@FFBEFCIHB
@>chr21:9661704-9661771-2
GAAGGTCCTCTGCTTGGGGGTCAGGGTCAGGGACCCACTTGTGGAGGCAGTCTGCCCNTTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
AFEDH??FHAEHHEC?ECGIGB??CH??EBDHBDA?C?CGF#FADAGIFADACII@@:IBGIDFCCEG??AGGB?DG@IGGEAG?ICFHH@GFDEHEHCG
@>chr21:9661704-9661771-3
GAAGGTCCTCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCTGACCNCCAAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
DCIDHDDH@GGA?FEG@ADFH?@CD@I?DDH?A?B?HDDEGCHBGCBBE@CCA@DA@CFI?@IGIBC(DDIEFICEA?BACE?ADIBBDG@BF@FACHAE
@>chr21:9661704-9661771-4
GAAGGTCCTCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCGCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
AH?CIHC?DHBIIA@ABIIEH?E?AC?EFAI@CDCBEIADIDIFE?BBDFBAHE?D?B???BCGGBAF@DAFDDDEAFAD?DH@BIF@BDCIAIFDDAAF
@>chr21:9661704-9661771-5
GAAGGTCCTCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCGCAAGTGGGTCCCTGAACCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
IC@CDEGE?CDC@@GCDEFFF?FEDHHCIBGA@CFCF?DAHCGFDAIDHGF?CAEFI?D2ADIHBEI?IBBEGID?E?B?CBE?GDHHDGICCBFE@EII
@>chr21:9661704-9661771-0
GCGGCGTACTGCTTGGGGGTCAGGGTTAGGGACCCACTTGAGGAGGCAGTCTGCCCATTCTCAGATCTCCANCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
BI??EAHF@GB@EGCDEDFEBIFFDC$D@@FHICGHAGCG@GGAEFIH@F?HHFE?@FHAEHCFIHHB,CG)DHDBHIADHFCG@I?C??CCFCGHABCC
@>chr21:9661704-9661771-1
GCGACGTACTGCTTGGGGGTCAGGGTCAGGGACCCACTTGAGGAGGCAGTCTGCCCATTGTCAGATCTCCAGNTGACATCGGAAGAGGGAAAAAAAAAAA
+
CGA2DFGIEGHFHIHDD?CI?GGCGICF@GAFA?CBEF?CGAFFHDB?HAIG?FDHI?H-?GCHDDC#?CBF,GDI9FBGIAED?CA&E?CHED@@FHF@
@>chr21:9661704-9661771-2
GCGGCGTACTGCCTGGGGGTCAGGGTCAGGGACCCAATTGAGGAGGCAGTCTGCNCATTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
@@?@@AGICDBB!@IGDHHHCEC?IH?FHCG@C?@F1FGA@EEADHBHGHAAAA3IIEFG?HGCBHBDAH@BC??CF??CDGAE@DII?BAEGHCFIHF@
@>chr21:9661704-9661771-3
GCGGCGTACAGCTGGAGATCTCAGAATGGGCAGACTGCCTCATCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGATGAGCGAAAAAAAAAAA
+
CE@FEDDIE@ADD5HFBGF??<FGHHCBCIEDAD?AIC?FG'?CFCFAABGHIB?BH@AAAAEHC@I?DB@FCCIFG@EADC@2BCIIAEHHDBA@GBGA
@>chr21:9661704-9661771-4
GCGGCGTACAGCTGGAGAGCTGAGAATGGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCTGACCCCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
EFCCEEIFFH@F@BGBDD+@FHFFAA@GFHA@D@DADIC?CCEG@AECF@D@?B@GCA?HEEAFDBCAF,EF@EGICHHBHIE?HBCCFE?BFAFCCEHH
@>chr21:9661704-9661771-5
GCGGCGTACAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCTCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
HBCEBG??EBIGFE??FAGIIFFIEDHA@CFIDBIID?ABGEBD?E?AC?AECCE@GG@GADIDGAIDIIIIBB@HAGEBFDGBEAHDB@BFIFAIBDG?
@>chr21:9661704-9661771-0
TCAGACGGCAATCTGCTTGGGGGTCAGGGTCAGGGACCCACTTGCGGAGGCAGTCTGCCCATTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAANAAA
+
B?@DH?BF-??E?HIHGFH?H?CG@AG@D?H?EEFADF?EEIDHFFHEIH?@?FGFIDHIB@IHGGE?@IG@ICH?FDEECFDAIAHEE?GDICEH*CDE
@>chr21:9661704-9661771-1
TCAGACGGTAATCTGCTTGGGGGTCAGGGTCAGGCACCCACTTGCGGAGGCAGTCTGCCCCTTCTCAGATCTCCAGCTGAGATCGGTAGAGCGAAAAAAA
+
FH??E@BFIGBFC??CCD@DE@EDFCIGDB@?GE2@ABBFE?A@CFHHCEH?CB?AG?DI"CGHFHACFIGHEEAHHFGDG@ABDG/IDGCF@ACCCGBB
@>chr21:9661704-9661771-2
TCAGACGGTANTCTGCTTGGGGGTCAGGGTCAGGGACCCACTTGCGGAGGCAGTCTGCCCATTCTCAGATCTCCAGCTGAGATCGGAAGAGCGAAAAAAA
+
C?IEHBCGBA*D@?IIH@?GD@GHHD@CFCFI?DCFIDI?ECHFI@FCDFFCF@EFDAFGCEAI?F?CAEDGHDFC?CG??@HBAGF@FD@GEAFA??HD
@>chr21:9661704-9661771-3
TCAGACGGTAATCAGCTGGAGATCTGAGAATGAGCAGACTGCCTCCGCAAGTGGGTCCCTGACCCTGCCCCCCANGCAGAGATCGGAAGAGCGAAAAAAA
+
GEDDB?AFDAFBEAD@EIHEDDBGDDHDAIB@!@GCFHDBDEAE@DFF@@?CDGA@HII@HHIFAGH3HDFCE?'EFD@HGC?GDH?EIIDEBHBF?BB?
@>chr21:9661704-9661771-4
TCAGACGGTAATCAGCTGGAGATCTGAGAATGGGCAGGCTGCCTCCGCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAA
+
E?EG?EBGIC@IH@CFBGBCHAG@FIDCD@GAEDFAI)AGGAEF@AH?A?EAAGBD?HAI?@IHGBDBHDCEB?EBFBCGB@@@GHABHHECHFBH@@HB
@>chr21:9661704-9661771-5
TCAGACGGTAATCAGCTGGAGATCTGAGAATGGGCAGACTGCCTCCGCAAGTGGGTCCCTGACCCTGACCCCCAAGCAGAGATCGGAAGAGCGAAAAAAA
+
FG@EDCHBCDHDGB3@HAGFG@F@H@CI?A@E'GCECIGH!DAEBB?BEF@CCCEGCCHHHCBFF@F?ADBIEF?B?GA?B?DI?FIHGGIDGFBAGBEA
@>chr21:9664845-9664970-0
ACCACTATGTCTGCAGCTGTGCCTGNGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCAGCTTCGAG
+
IC?IAAAHE@IFA@CGFHBEHBHAA+I?IH@AH?FE?GAB?FGDIFIIFAIGH@GHA@BH@GAD?HAF@HCFIICBFDGF@@EI?GICIA?EE@EAC@@I
@>chr21:9664845-9664970-1
ACCACTATGTCTGCAGCTGTGCATGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACNCGTTCCTGGCTCCCACCAGCTTCGAG
+
CCFDCBBIEBI@@CAEHBC?EF'HACD@HACH@GGF?DFGABF@C@CD?FEAEGBBCDADHA?AHFCDEFABI%FFC@B@F@AFD?GFGCFEAFD@AEHE
@>chr21:9664845-9664970-2
ACCACTATGTCTGCAGCTGTGAATGTGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGTGTGGGGCTCCCACCCGTTCCTGGCTCTCACCAGCTTCGAG
+
GAGHAEGEDG@?DG@CB@FCB*.IF;CHFCEGFAAF@DHBHIDBB@@GEHDI?EBDEIC;EBBFIACGEGCBFEDCCEBFEF?@@B.DBBBBADACA@BG
@>chr21:9664845-9664970-3
ACCACAATGTCTGCAGTGGGGAGGAGTGGCTGGGGCTGTGCGCTCCTCGAAGCTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTATATTGGC
+
IHB?A4@EDBH?D?@?BDHBECC@??HDFH@CDA@BBIBCBAEHCCHEGHE@FCIDDDEDAHHECI?HAIAI-EH@HHGEGEAHFIFIBBF?D/CFFI@?
@>chr21:9664845-9664970-4
ACCACTATGTCTGCAGTGGGGAGGAGTGTCTGGGGCTGTGCGCTTCTCGAAGCTGGTGGGAGCCAGGAACGGGTGGGAGCGCCACCCCTTCTAAATTGGC
+
BB?DI?HI@B@CIDFDEADGDI@AAGG?=GIBEH@I?BC@GEIC)D@D???HI?CFCFICEFEA@HGG@ADBHGAIBGGA9?FHDBEDD?HDA?D?DBAH
@>chr21:9664845-9664970-5
ACCACTATGTCTGCAGTGGGGAGGAGTGGCTTGGGCTGTGCGCTCCTCGAAGCTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAAATTGGC
+
@HG?ID@?AAAECDGHE@?H?AHHC@FBCAB0DEDB@FDEFEGECHGG?DFGFIAHEC@FAA@?ICEBAG?BI?EGFAI@F@G?BCICBD@BF??I@AE@
@>chr21:9664845-9664970-0
CTCATACCACGCTTCAGCTGTGCCTGGGAGGGCGGNGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCACCTTCGA
+
CCC?I@FCHE?@A(CD@CIE?HIHDH?D?BC?A@F+F@IBH?@BABDD@IFH@?IAD@HCHHFHAIBCGGHGDF?IBF?AEDBIEEACHDAHGG?F@A@A
@>chr21:9664845-9664970-1
CTCATACCACGCTGGAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCAGCTTCGA
+
IGI?ECHH?IEIAD4@GFEHHD?E@EGEFIG?EFIIGEDBEGAIBEIAAHHBA?CBEF@EC?BCADGFDBG?AD@ECACCGFGFC@IEEDDEGA?@BD@B
@>chr21:9664845-9664970-2
CTCATACCACGCTGCAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCAACCGTTCCTGGCTCCCACCAGCTTCGA
+
F?EIG?@GI@GF@EBBAG@CIII?CHHECF@IG?@EGCCEGBAGA?@HEC?AE@?DD@B@@IHGG@ECHCCDF)IC?DA??AA?HHEGD?G@GIIDDG?F
@>chr21:9664845-9664970-3
CTCATACCACGCTGCAGTGGGGAGTAGTGGCTGGGGCTGTGCGCTCCTCGCAGCTGGTGGGAGCCAGGAACGGGTGCGAGCCCCACCCTTTCTAAATTGG
+
HAFBBH@EH@BB??@GE?GCEB?B.DAIEAEDA?IIC??EH@AHFACFG?8IIGEH@ACACC?GFDBFI@H?DBH@=II?B?BAHHDH;@CCHEGDB?EG
@>chr21:9664845-9664970-4
CTCATACCACGCTGCAGTGGGGAGGAGTTGCTGGGGCTGTGCGCTCCTCGAAGGTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAAATTGG
+
B?IIBHBABDC@BCGGBH?BF@GGE@EB>EH?BGAAAG@BC@?GAEAICAAGCI@@EICEH@DCGDFGADGCEGIGAGCCI?HCDGB?FD?FGCGABBB@
@>chr21:9664845-9664970-5
CTCATACCACGCTGCAGTGGGGAGGAGTGGCTGGGGCTGTTCGCTCCTCGAAGGTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAAATTGG
+
F@CADIFEA@GGIDF?FIBBCICHEAAD@IDC?BABHE?@:DIGAGDFHHIGGECBHGIFIIFEE??C?D?BIFBD@FBBEIG?CHHHAAEI@BE@@D@?
@>chr21:9664845-9664970-0
GAAGGTCCTCTGCAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTANAAGGGGTGGGGCACCCACCCGTTCCTGGCTCCCACCACCTTCGACG
+
@AEE?AFIDBBF@HEACEEG@CGDFD?CIC?BBHDIICAIACHFBHBIGBCB?%@BEEAEC@II@E:ED?DDI@CCBIFAEBHIICABEABF@H@GDF9A
@>chr21:9664845-9664970-1
GAAGGTCCTCTGCAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCACCTTCGAGG
+
CIHEF?HAGIHGHDICG?DGGH"IEHHCGHGEAA?G?HCIGHAEHFBB@EDEGBHEBI@??AHHIDBIDAA@D@?B@?GID@BHCAFECEIEHCC@BHGH
@>chr21:9664845-9664970-2
GAAGGTCCTCTGCAGCTGTGCCTGAGAGGGCGGNGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCACCTTCGAGG
+
G?DF@DFCCDGAGFFGFI?H?GEG!@F@B??H@<BFD?@?GEIBFE?7EGADDGCDH@HB?FCCBIAADB??GHCGDBBGHFI?FACCD@AH?I?CF?BH
@>chr21:9664845-9664970-3
GAAGGTCCTCTGCAGTGGGGAGGAGTGGCTGGGGCTGTGCGCTCCTCGACGGTGGTGGGAGCCAGGAACGGGTGAGAGCCCCACCCCTTCTAAATTGGCA
+
IGGA?@CCF@H@EDIBIFCFG?IA?HH?D@?ICIHIDAHDIHICIGE@?3CAGCGGACEBCH@?@IGGFGAEA@$@BC?@FED?EFGABAI@FFCABAD@
@>chr21:9664845-9664970-4
GAAGGTCCTCTGCAGTGGGGAGGAGTGGCTGGGGCTCTGCGCTCCTCGAAGGTGGTGGGAGCCAGGAACGGGTGGGAGCCCCANCCCTTCTAAATTGGCA
+
CADIHC??D@GCFC?@IFDDH@HDA?FEBGAGC?DB2CHBGADDEGF?IFGI@BAAIIHGGHGCDIFDFHGFEBIAIBIB?ED+BE?DGIDFGEDEIDII
@>chr21:9664845-9664970-5
GAAGGTCCTCTGCAGTGGGGAGGAGTGTCTGGGGCTGTGCGCTCCTCGAAGGTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAAATTGGCA
+
BAADIHFI@EBDH?AH,DDHHG@I@GH!HHGI@HCFC?IGCDDC?IBGAFG?BEFF?FH@CEDAB?HHDDCADGEA@A@DIGCDIA@EIH@BAA?IDHAC
@>chr21:9664845-9664970-0
GCGGCGTACTGCAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCACCTTCGAGGA
+
I?DFFA?EEFIBHIGHI@HGD@GHG@FHH@DBD@@HG??@AIHGGGGCHGGCCBBIBEHHBDHG?@DHA@ECBEG@CBDIEECIGFAD?ADID?C@FD?B
@>chr21:9664845-9664970-1
GCGGCGTACTGCAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTNCCAATNTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCACCTTCGAGGA
+
FHF?GGIE@BAF@BF?FECBBH?C'EBA?BAIABCFEGCCDDE6@FFCF-AB@G@@BGGIHEFDDEBBA?A?EDEABDH@DEADBBGDIEF?DAEIFBFA
@>chr21:9664845-9664970-2
GCGGCGTACTGCAGCTGTGCCTGGGAGGGAGGGGCTCCTGCTTGCCAATTTAGAAGGGNTGGGGCTCCCACCCGTTCCTGGCTCCCACCACCTTCGAGGA
+
@CHG?B@B?A?HBFDDGBDGEEDD?AFI?9BCDEIAE?CGCFDCCI@DBB@AGFIDHD/EF@@?@CEAFIFH?DHI?ADBA@FB@@EFG@@I@CHBAE?G
@>chr21:9664845-9664970-3
GCGGCGTACTGCAGTGGGGAGGAGTGGCTGGGGCTGTGCGCTCCTCGAAGGTGGTGGGAGCCAGGAACGGGTGAGAGCCCCACCCCTTCTAAATTGGCAA
+
EEEFACBDIAD?C?CIEF@BBBIE@EB??DDFHBGGCH@AGI??@HIGCCAF@BH@?FB?CGA?CIA@CCHB?#IAEE?CA@BI?A@FH@CDFADI?EII
@>chr21:9664845-9664970-4
GCGGCGTACTGCAGTTGGGAGGAGTGGCTGGGGCTGTGCGCTCCTCGAAGGTGGTGGGAGCCAGGAACGGGTGNGAGCCCCACCCCTTCTAAATTGGCAA
+
?@@IEDDHEED@GII*GACGED@IDHAID?BAG@IDA@BIDA@IAG?G@G@GEG@CI@B@EA?HIABEI?I?B6GGBF?ABI?ID?F?IEFHCHFIC?D@
@>chr21:9664845-9664970-5
GCGGCGTACTGCAGTGGGGAGGAGTGGCTGGGGCTGTGCGCTCCTGGAAGGTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAAATTGGCAA
+
B?CEHE??BHDFIBA?HBDEC@@I@E"EABCHIA@FHC@GAIF?D"IBDFDCAGBHEBEIFD@??GIGAAECBIHHGBA@?BI@CHDEGF?BHAC@G@DG
@>chr21:9664845-9664970-0
TCAGACGGTAATCTGCAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCACCTTCG
+
DFAAFGDEBH???GI??EGDHDHH@ABFHHEE@BIIDECH?CFDAAFAI?IBHDCFAA@BF?GBDBEI@@E@H??HBBFCFHIAFEHG@FCGBAAIBI@I
@>chr21:9664845-9664970-1
TCAGACGGTAATCTGCAGCTGTGCCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCAGCTTCG
+
DB?FEFC?D?BFDBHIHBBBHEFGFD?@?IC@IFHEIDDFD??DHDDHGADBB@GCIEF@EDAFH??GD?AGHA@CIBD?A@ABDHCIHF@IIABBCDCI
@>chr21:9664845-9664970-2
TCCGACGGTAATCTGCAGCTGTACCTGGGAGGGCGGGGCTCCTGCTTGCCAATTTAGAAGGGGTGGGGCTCCCACCCGTTCCTGGCTCCCACCAGCTTCG
+
BH7.EI??@EHG?@DEAD?EAG%FD?DGAEGFFF?HBFBFDCAFCD/CA@@GI:IGFE@GBIEB?FH@FIC@@@DA@@ADD@?DIIIIEEA@HEAAGAFF
@>chr21:9664845-9664970-3
TCAGACGGTAATCTGCAGTGGGGAGGAGTAGCTGGGGCGGTGCGCTCCTCGAAGCTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAAATTG
+
ICC?FH@BD@CB@IEIAGGFIGA@H@EHA+?GGFA?BH9D?DACAH@@AADHHHDHEAH?AGG?E@H??A?EHBABDCHDHBBF@BDB@?CCEIC?AHBE
@>chr21:9664845-9664970-4
TCAGACGGTAATCTGCAGTGGGGAGGAGTGGCTTGGGCTGTGCGCTCCTCGAAGGTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAAATTG
+
DDDCCC@ABBBADDBAF?H??GBBIEHBD?BFG=DAEDHG@F@D@IB??DCFE?FAFGEHBI/IF@BIEA?EHAFEGBEHFIIFGDF@ABCFCFBAHDAH
@>chr21:9664845-9664970-5
TCAGACGGTAATCTGCAGTGGGGAGGAGTGGCTGGGGCTGTGCGCTCCTCGAAGTTGGTGGGAGCCAGGAACGGGTGGGAGCCCCACCCCTTCTAGATTG
+
G?HDECFDE@BFIGHCIGFI?HBFEBCDBD?AHEC?@CIED@ECD@AFFIEBHF4BFBG@FGIEC@DEADEA?DAE@BIHIGHAGCFIEGCGAAB;?C?@
@>chr21:9665938-9666124-0
ACCACTATGTCAGCCAGTGACCCAAAATGGNATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCCT
+
AHGFFEGB&@DAACEGCDA@?B?FCEB@IB<B?@@<EF@?HCBID?CHCEC@BBAAFBH?CE@@)ADB?ECIBDDCDF@FIHAE??ABABEBBE?I@DHE
@>chr21:9665938-9666124-1
ACCACTATGTCAGCCAGTGACCNAAAATGGGATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCCT
+
GIG?IIEGAHB@ABIAEFAGG?#CH@FGDCICBCGICAD?@?FGAGG)?GGAIH@CDCFFIAFGHGDGIHECH?DCAHDHCHGAG@EHIGHHFCEIFGBG
@>chr21:9665938-9666124-2
ACCACTATGTCAGCCAGTGACCCAAAATGGGATTTATTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCCT
+
BB?GHAFGI@CG@IBH?DA??ABCFHAAEFD?BB@)EH@?ECHEDGFC???EABA4EA?HDG?H?E@@D@F?C@@@EDIBBEECFHGACIBCBIIGEBBB
@>chr21:9665938-9666124-3
ACCACTATGTCTGCAGTGAGCCGAGATCACACCACTGACCTNTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAAA
+
AFDEH?CDCFGDA?F@BFIGCBDFGHIFBEE"?CGGB-FGA;BAADIAHDB?GECGCAGDFECHFA?AAB?C@FACHIB@CIFIBDACBAG@H@EBGIBH
@>chr21:9665938-9666124-4
ACCACTATGTCTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTCAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAAA
+
?E@BHHIBFIF?EC?@C?FGGIBCIHDD?F?@?@D?HG@GCB<CBFBD?AEH@AFDBF@FD;EG@EFGB@?FCHABFBHDDD?HDDIAD?EBIIIIBACD
@>chr21:9665938-9666124-5
ACCACTATGTCTGAAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATTAA
+
GHEDEF?EF@CE@)EDGIGIHDH?DBI?EHHCHHCGBGGHDFD??@ACEIDCFE?DFCDDABAHF?CFGAGEE?DHEHHG@BF?CI@CBFEE?HEEH!DE
@>chr21:9665938-9666124-0
CTCATACCACGCAGCCAGTAACCCAAAATGGGAATTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCC
+
BIEFCIBF?BGDG?EIE?C)BDE???CABEAGDE@A@DDIFAIEBEI?EBBEDACFC?ACD?C@EAIDEDAGEG?EEF?F??EHC?ABEEEHAA?EBD?D
@>chr21:9665938-9666124-1
CTCATACCACGCAGCCAGTGACCCAAAATGGGAATTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCC
+
BC?@CD@AC?FA?EFBE?GFCD@IAII@CDBF?GF??HIEC@FG@BDAEACHA@GHDFE@?F?CEFIAD@EF@GABBBACIGIHDIGGGGBFC?IB?FFG
@>chr21:9665938-9666124-2
CTCATACCACGCAGCCAGTGACCCAAAAGGGGAATTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCC
+
GD:@CHCCE@HBBC@HG@DFBHCFIIFG&HFDHF?AF?C@G@B?EI?ACBHFIFBBAF@BEGI?B@BGIH?BAG?AB@ICDAC?IIDCFDGIIHBDIDC@
@>chr21:9665938-9666124-3
CTCATACCACGCTGCAGTGAGCCGAGATCACACCACTGTCCTCTNGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAA
+
DC@I?AA@EDD?EGB?EGEA@DD?EC?FDI?@BBAEBEBBECHI/ABHDCCFG@E@AICBDGGHHCEBIFIA@IHCH?HHFHG@GIDEB?@DFABDDHDC
@>chr21:9665938-9666124-4
CTCATACCACGCTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAA
+
AAACDB@DGFGHAH??EHG@CIGEDEH@AFFBCIH??ADE@D?EDGEBAF?DEHEEHGID?GHBFH@C@DGI?ECG@IFI@AAGH@IHFFB@AFHBHEFD
@>chr21:9665938-9666124-5
CTCATACCACGCTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAATATTAAAAATAA
+
B?FHI?A@@CAGEIEGCH@F@HFBAAHD?@EEGDIGIGBIHHE?CEEACDGE?GHAAGCEB)FHFEAHCIIBDHAFIHBAGIABE?HD,E@EA?E?@AD@
@>chr21:9665938-9666124-0
GAAGGTCCTCAGCCAGTGACCCAAAATGGGAATTCTTCTGGCCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCCTT
+
CHEEFIBGA?FC@AHEBGDCE@CBGHG?ABCGEBED@?EAD,IEIE?FIHA?HAAH@@CFHCGBIDEICABGIIFFBIIFI?AB?@EA?ECFIGE@CFHE
@>chr21:9665938-9666124-1
GAAGGTCCTCAGCCAGTGACCCAAAATGGGATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTAGTTTTGTTTCCTT
+
?IECGBFBCCIFFCEFD@??HFHEEG?G@EFAGHC@ADIGAAAFDBHHCCGFHDE@FDHECCBID@AA?HCGHE@DEIGED?EBCCA+?EBHBEGBCHFI
@>chr21:9665938-9666124-2
GAAGGTCCTCAGCCAGTGACCCAAAATGGGATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTCTCCTT
+
C?GFF?B@BBGEEEC@GGFFCHBEGEICF??@BCFD?DIEBH.CHBC@BF@HECHEIEBEC?FCEHECAD?EBF?DFICHADBI?GBEHGGBGI=FCGGF
@>chr21:9665938-9666124-3
GAAGGTCCTCTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAAAA
+
IAEGAIHCHIFC?@F@@@FCADIAIHFBAFCCH?AIHECCECDE@@?EIAAI?I@D@@HIICFC?IHFBFGAHFAACEBGI@BEH@IIIHD?FDBEFHCC
@>chr21:9665938-9666124-4
GAAGGTCCTCTGCAGTGAGCCGNGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAAAA
+
AGD@?BB?FG?@A@ABEEE@GC/EDC@0GCGDBIFIBI@BI?BCDCD@B?BG;IFIDI?@FF?BGHIGFBIAHBHFBD?H3AD?DBCBD?CHI@HBGHHA
@>chr21:9665938-9666124-5
GAATTTACTCTGCAGTGAGCCGAGATCACACCACTATCCTCTAGCCTGGACAACAAGGGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAAAA
+
?A@:5G:H@???DHDB?1BEDGGFBA?B@?H??BE8FABAHDIEEDID@BADIEADG:BBFGHDGGI@ACBBA'GHCCBH@I?FBBBHGHBFAIDDGG@I
@>chr21:9665938-9666124-0
GCGGCGTACAGCCAGTGACCCAAAATGGGATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTTGTGTCAAGCCTTGTTACTTTTGTTTCCTTG
+
HEBI@BDGE#DACBHICDCFGBHGBHIB?EEHGHI@HHFAHHE@AG@FEB?ABIDFDCBHHFBDBICIH>?IEEBA@HCBIAEBBBB@CA@CEBG?B@CB
@>chr21:9665938-9666124-1
GCNGCGTACAGCCAGTGACCCAAAATGGGATTTCTTCTGGGCTTTTCTTACTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCCTTG
+
AG6AACCGHGCEBIAICAAE7G@GAF?CGHGCF?CHICDBIE?FHC@CA)EBFF@DHAFEDDA?HDEE@CBEB@B?FDGFD?FC@DABFGHI?H@CFFFG
@>chr21:9665938-9666124-2
GCGGCGTATAGCCAGTGACTCAAAATGGGATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTCCCTG
+
F@EI@?D@:FB?AHAHHD?<BF?FAFDHDEA?CB?C?CFBFEABCCF@H?C@ADBBH@IAFIHFE@AEBA@HBF@GA??C?GECFHDFB@AGEIDDA'HB
@>chr21:9665938-9666124-3
GCGGCGTACTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAAAAG
+
B@FGAHAIGFHE@CAHHE??@CIIGGE@I?EAIHIFHBADIFACHIFGIGDHDEFEAIIGECCCFB@@BFFD?D?ABEADHI?ABB@GH@GBGCHDFD@F
@>chr21:9665938-9666124-4
GCGGCGTACTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAATAAAAAAATTAAAAATAAAAG
+
AFIBCFGDBE?CFFE@GFDIBADIAGGHFI?BCFG?ADFCH@@?EGAFHG?AHG??CEIIBGGHEHD?CCIA@D@IAGD*?F?A?@DIGIHDBFGAFGED
@>chr21:9665938-9666124-5
GCGGCGTACTGCAGTGAGCCGTGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATAAAAG
+
@FFIBGDAHD@@DBAGDHFGG6EABG@AEAE?HII?AD@EAEADBHDDFEDCHDEHF?AICBIFBA?ICB?AEBHFCHGF@AEBFAAGHBHBDEEIGCHG
@>chr21:9665938-9666124-0
TCAGACGGTAATCAGCCAGTGACCCAAAATGGGATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTC
+
FIDFF@GHFCFHGAFHEEHGHGHEEI@F@ED@IHG@IB?@BID?CHC;DHIDIHCC?A@?CFEE@EDB?@@DGFGAEAIDIDEECBDA@B?G?FDIB?I?
@>chr21:9665938-9666124-1
TAAGACGGTAATCAGCCAGTGACCCAAAATGGGATTTCTTCTGGGCTTTACTTGCTTAGATTCAGGCTCATCTGGTGTCAAGCCTTGTTACTTTTGTTTC
+
A:GFDHECFIEC?GEHGHGFGDIA?BIAC?ABAIIDFACG@GGF?BAI?2H@ABD;EIAA?EH@HED@D@D?FCCC?IBBE?AA??BECFDEDEIA??A?
@>chr21:9665938-9666124-2
TCAGACGGTANTCAGCCAGTGACCCAAAATGGGATTTCTTCTGGGCTTTTCTTGCTTAGATTCAGGCTCATCTGGTNTCAAGCCTTGTTACTTTTGTTTC
+
DAAC@DIICE7EFDIF@ICB?AE?C@ACF?IHBIF?D?DG?A?@FIF?C?FBFCDG@DD@DHB@BDDFCIDH?H?E6HDC??FDICFIIBBIEG@GAE?F
@>chr21:9665938-9666124-3
TCAGACGGTAATCTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAACAAAATTAAAAATA
+
?C@CIIACBB@ICFAFA?IDDEI?DD@??A@CH@DDHHG?DBC@@BDBDHEH?G@FGIBEEEA@?E@FCF@EE@@HAFH?BFIHED:HEIEE?IBDD@GF
@>chr21:9665938-9666124-4
TCAGACGGTAATCTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATA
+
?DBHDD@@FDCIFADHIFC@C?CF?EF?IGFACGEEDD?E?EEFAHADEGI?C@C@EI?@DFE?G?FGBGBHEAE?G@HGA?@DHD?BDDI?I?FEF@ID
@>chr21:9665938-9666124-5
TCAGACGGTAATCTGCAGTGAGCCGAGATCACACCACTGTCCTCTAGCCTGGACAACAAGAGTGAAACTCTGTCTCAAAAGAAAAAAAAAATTAAAAATA
+
DD?DEEADACC@ACBGGCC?HGI?FBCFAIIEBF?HEGC@AAAAEEI@CIAC??ECHGBGIEGE?AB@EIGDFCA@EFDBI@DCEFFABIHGHEIB?EBD
@>chr21:9667509-9667698-0
ACCACTATGTCAGCAGTCTTTAATAAACCACCGCTTGTCCTCTGGTCGCAAACCATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAAGA
+
FHFIEC@E?IC?G??BA?C?HCHCFEA@BAD+IGEFCIAECD?C(HHACEAGD3@@GGBF@F?AFDHIHGCBHBDH@@BDIF@?C?HADB?A?H?D@DA?
@>chr21:9667509-9667698-1
ACCACTATGTCAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAAATATTACCATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAAGA
+
EIBDEFDCBEI??GHB?FGIECIHFABHDFIEE@CGAHDAF?EHEIICB?C?4@H?A@$GBH@@F?8F@GB@E?EGCAH@B?HH@IBG@AHCCBA@?AF@
@>chr21:9667509-9667698-2
ACCACTATGTCAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAAGA
+
DAACD?GGIDD?EH@B??EBE?FFBB@ECHGEGCB@GBEHFFBF@IE@GAB@EHGBAEIB@E@@GCFBICIEGFADEHHCFEHFDECG?HB@@@G??BEA
@>chr21:9667509-9667698-3
ACCACTNTGTCAGCTGTGTGTGTGTTGGTGCAGANGACAGGCCACTACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCAGAAGGAAAACCA
+
FACADH1BED@IAHACEHECI@FGCHB?HEAIC?-C@CGIGEICGCGC?FIG?HBIFEIG?ECGHH@HEBGBIADDBI@CEGC??EE?.BEIBD@CHH@B
@>chr21:9667509-9667698-4
ACCACTATCTCAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCTCTAGAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACCA
+
A@BE@AII8?H@CG@HBAIHH?CC@?DGI@FDA?HIDB??@D@;IGH&EIIADI?IIFA?BDDC@AG@CGAFEDECFDIDHIBFAAIF?IBD?CEDECEF
@>chr21:9667509-9667698-5
ACCACTATGTCAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCACTACAACCTGATTCAGGATTCAGTTTGGCTACCAGCCAGTGCCATAAGGANAACCA
+
FCIG@FCFHF?GGHGI@I@II@@HEF??HHADACDGIHFAAIBD?EEBCEGGHEAAHFE@CGHDABB@?%GECC@HCIG?GFB@DGCI@EIAAF(?GBHE
@>chr21:9667509-9667698-0
CTCATACCACGCAACAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCNACATGCAAATTATGCTTTGCCCCTCTCAAG
+
FGABHC@EIEBHI'GICEH@CE?BDHC@ICDCFCDGGAGIDE?HCDDDIDH?I?A@IEDED@CI@F@HH1GB?HGBDD@BII?DCACBD?BIFHBDC@@B
@>chr21:9667509-9667698-1
CTCATACCACGCAGCAGTNTATAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAAG
+
ACDIFGFG@D0IBAA@ED#I/?BE@BGBHBIGE?CBFCECA?@HHFCHE?GEHIIB@FEGCCC?CAHHDE?@AGFCA??ICDC?IEGCHHFBACIE?@GB
@>chr21:9667509-9667698-2
CTCATACCACGCAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATACANATTATGCTTTGCCCCTATCAAG
+
I@EAEBH@IHFC?DDHIFHBH@G@D@GAB?BI@@E@EC?@IHF?AIAI?IBAF?FBGDH@ABABIIGEBGEHE?8AG;IHAB@@CBBFG@HH??/GIC?@
@>chr21:9667509-9667698-3
CTCATACCACGCATCTGTGTGTGTGTTGGTGCAGATGACAGGCCACCACAACCTGATTCAGAATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACC
+
GI@IGBC??F??D$@F@GDH@?GCIAD?CA@FB?BAIAGEDGIA@IECG?EDG'AIFGEF@2BAHADBIDHGEBBCGGFC?EDCEG@HC?FBH?ECBCAA
@>chr21:9667509-9667698-4
CTCATACCACGCAGCTGTGTGAGTGTTGGTGCAGATGACAGGCCACTACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACC
+
HH@CDCCFE@BGHAHFHHBB@:ADG?FE@CEG?@CG??@@@EA@B?FDIB@?BCBF@@HE@DEF@GIEAF?BIGBDFGBHF@BHEIEF@CDAA?D@F?CG
@>chr21:9667509-9667698-5
CTCATACCACGCAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCACTACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACC
+
@HII?E@BE@I?EBDGDEC@FFEHBA?BEGCEGBAHHICAGCGIBEAH?DAIAEAEI@IE?ECDFEFCABHC@GDI?A@D??HHFEHGEEHDBCCFGBFG
@>chr21:9667509-9667698-0
GAAGGTCCTCAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAGATTATGCTTTGCCCCTCTCAAGAG
+
AH?B?A0?HB4CA@@@CHFCBBHCC@GFF?ADFHFBGFEI?EFIBHAFDFBH@A?A@A@?IDAIGEBCEFFCCAF;BHHHADGFI?AFDCDBAA?IHGGA
@>chr21:9667509-9667698-1
GAAGGTCCTCAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTAATAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAAGAG
+
?A@A3GHCEIHAHAHHDDFEACHIDHIA@BEBHI@?CGBEC@C?BC@@BABHAH5@IIFBF?IEGEDGIACFCEHFE?GBE?HAIGF@IHDE?GEDEDAH
@>chr21:9667509-9667698-2
GAAGGTCCTCAGCAGTCTTTAATAAANCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCGCCTCTCAAGAG
+
DFDBI?E?DEE?D?H@A-BIFAF?GC6?EIGCBH@A@@HAA@0CB@CGA@FGGCD?CB@GIACGDIG@FD?B+ECGEIGGFDBHCFHB3CGB@@@BGGAE
@>chr21:9667509-9667698-3
GAAGGTCCTCAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCACTACAGCCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACCAT
+
BBCFH?FB+DED?FG?E?6@HDFH@EAFFG@HG?DFFAG@HAGIHADC7GECIH???CIGDFE@DF@BBCBG?CAACIFAH@@?GHCHAHGGBBGBIDFC
@>chr21:9667509-9667698-4
GAAGGTCCTCAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCACTACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACCAC
+
H@IFFC??CD?A?HCIHCCFHBCIDAF?HFAFIHBIHBB@?AGDFCI@EB@DC?EDGFEICBAGCHFFFEID?FEBIFAB?GI@GI@DI?DIFCDAG?B8
@>chr21:9667509-9667698-5
GAAGGTCCTCAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCACTACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCCTAAGGAAAACCAT
+
?IC?@AIBEAFECFG?AEID@HFCIBCG@HAFHCECGD@GEH@HHBGHBB@I@FBA@>CAGCHB@HGDBAIGAIDC?AHBGHDF?B6?DIGAHHFDDHCD
@>chr21:9667509-9667698-0
GCGGCGTACAGCAGTCTTTAATTAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAAGAGC
+
??IICDIHHEC?CH@CCGEABF.?D@IDHE??HCGFDEAD@@?CHHCEICDEHIABFEEBIIDGGFIBAAE?@DE@EAI??D?DEACIHBCHE@CC?HDH
@>chr21:9667509-9667698-1
GCGGCATACAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAAGAGC
+
@DECD9G@D?IIH?EGECEBBIIIBFCHC?IFCB@@@FIGAGAIIEH@?BDBG?A@AH@FEBAHGBBH@?EE?B?AEGCFICEIGIECCFEBEB@B?A?D
@>chr21:9667509-9667698-2
GCGGCGTACAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAANTTATGCTTTGCCCCTCTCAAGAGC
+
B?DH?ID?AECH??E?BDDDAGHI?F@@BAEIGB?HAEECHFIF?HCC@IEIFB@@FCFIFCFBC?HDAIGDEAE5@HCCGBEHFDE??GHCFC@BEBC@
@>chr21:9667509-9667698-3
GCGGCGTACAGCCGTGTGTGTGTTGGTGCAGATGACAGGCCACTACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACCATT
+
@IDAHDCHE?A@$HBB@HGHHBFHG@@?BB?@FCACIH@ECDH@IDEFACCGHEBHICFAGCBF@FDFD@BFA@?BABAAICGHB@HIIG@FBAI@D?@C
@>chr21:9667509-9667698-4
GCGGCGTACAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCACTTCAACCTGATTCAGGATTCAGTTGGGCTACCATCCAGTGCCATAAGGAAAACCATT
+
FDBGHCICHHE?HII?IDIFCEBCCCD?HIHCFD?CBFHA?I@D!C@EAH?AADE?GBID@?BCDDAH@AG@HBDI8CE@?EDDDGFEIBHDDDICGDCC
@>chr21:9667509-9667698-5
GCGGCGTACAGCTGTGTGTGTGTTGGTGCAGATGACAGGCCACTACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAACCATT
+
CGH?IFHHBFHAEBGECIDG?CGG@CDBE?E@BAIFCBFIBBCDGICACEBD?@IHB?IGDIABGIIIEDD?FAIEC@IBFAFGD?ABIE?AHGFEHAEA
@>chr21:9667509-9667698-0
TCAAACGGTAATCAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAA
+
@@D6@IBEDAI@G?HCEHH@BD@AHEH?F?EACHA?IFDB@EFACGFA@IH?HAHEF??HACICCDG@GADBI@H?HCBGEIEEIEEIB?EGCAAD@BFG
@>chr21:9667509-9667698-1
TCAGTCGGTAATCAGCAGTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAA
+
IFBB$IAH?DAHAG@HBC@CEGECDCD?C@E?BGHFEEG??@BCIGGI@DABFFEEDEFHHIEHDCC@GABE?C@ECDBFHCI?ED??HF??@CECCHFF
@>chr21:9667509-9667698-2
TCAGACGGTAATCAGCATTCTTTAATAAACCACAGCTTGTCCTCTGGTCGCAAACTATTAACATTTCTGCTACATGCAAATTATGCTTTGCCCCTCTCAA
+
BIFDCAFBCGFGEDHCI,CDDCGBFGACEFIFGAE?DIGG@@BBEFBBG?ABAGECHHFEB@GIADEBCA?AIG@EICC@BCBCG?AABAHH?IAAAFEI
@>chr21:9667509-9667698-3
TCAGACGGTAATNAGCTGTGTGTGTGTTGCTGCAGATGACAGGCCANCACAACCTGATTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATAAGGAAAAC
+
D?@?D@AA?DG@:F?F@AGGC?@?DAHCE+CGHBAACIFCF?BGHG:AD@H@EAHA?IFBFIFGDDBG?BDBAHFHAG@HB?ACB@EA@BAEGF@DAEAF
@>chr21:9667509-9667698-4
TCAGACGGTAATCAGCTGTGTGTGTGTTGGTGCGGATGACAGGCCACCACAACCTGTTTCAGGATTCAGTTGGGCTACCAGCCAGTGCCATGGGGAAAAC
+
B@HBEBFBIFFII?ABE#CBGCBI@BHHBACGB.HFH?GBA?2CA?CHIGDHBIBE0@DBGGCA@D?GGHE?HH@DEFBBFH?HB@FFBIA5#F?DBDCE
@>chr21:9667509-9667698-5
TCAGACGGTAATCAGCTCTGTGTGTGTTGGTGCGGATGACAGGCCACCGCAACCTGATTCAGGATNCAGTTGGGCTACCAGCCAGTGCCATAAGGAACAC
+
BGGIHBEIE@B??BF?A>@GDF?AB?GFC@CC@*E@EA?AAH@FDB?D2EHHID@BD@IHD@?DE'CFBAG?F@GIDBGHAFD@DE?B?DHIAAI?H0AD
@>chr21:9668603-9668674-0
ACCACTATGTCAGCTCTTTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGGAGAAACCATCCCCAAAACTTGGCNGAGATCGGAAGAGCGAAAAA
+
DA?HCGFAHABECIHACCGDIDEIHBAACCH?CB@I@BFH@IIIEBAA@D?BDHC%HHDAH?F@HIAE?CFA@?FGIGI4??AAABB?AGCF@BIEHB?F
@>chr21:9668603-9668674-1
ACCACTATGTCAGCTCATTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAAA
+
CAHDIC?B?EEBDE@?BDCIH@BIGGH@GGGEHCICFG@AHAFHHIAGHHHIC?@CG?CAEIFHHABC?FAI?@GDDEC?F??HB@?CFAGDGFAH??FA
@>chr21:9668603-9668674-2
ACCACTATGTCAGCTCATTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAAA
+
EE@GAGIDCD?BIFGCBGE?@@@CBF?FHBFGCGCIAI@GEBEBIFEGCA?HGCCBE@HHBFAGBBCGABD?F@DE@BACIICA@FEIDBAHAD?CCDF?
@>chr21:9668603-9668674-3
ACCACTATGTCTGCCAAGTTTTGGGGATGCTTTCTTCAGAATAGAAAACTGGAACAGAATATGACCGCTGGAAATGAGCTGAGATCGGAAGAGCGAAAAA
+
AFHE??GAHHBCHFHIAGFGAHABFE?BD&AEAHG@IAGDGHAFCDCDGFI@C@B?FFCABEFBCBDABDF?@@F?E@HGHFGFED?DE@HHI@HBC?FD
@>chr21:9668603-9668674-4
NACACTATGTCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGACAACTGGAACAGAATCTGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAA
+
->I@ACGBCCBGEGHCF@?F@ACHHBIGI?DD?DBCHDCFFCE?B+HHFGE@CABFBG@H5IFEBBCECGIEHIDIEGGEAIBFH?BA??I?EC=EHIHA
@>chr21:9668603-9668674-5
ACCACTATGTCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAA
+
ECFBF?AGC@DHEEDHA?F?CEBCIEEGFFF@FDIABDI?@GEDF?GB@GHIDBIE?CAAFAHFGD?ACEBFHEABE@@B?GHCGECABDGGEF@@HFBF
@>chr21:9668603-9668674-0
CTCATACCACGCAGCTCTTTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACAATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAA
+
CGECEAE3CFFFEHCF?HFH@GCE@CAAICGDBDE?IDBB?CDBIIHAAGC@F?CF@CGAHEC;CE@?EIB@HGADDA?A@BC??EBAHABEDB@HI?GF
@>chr21:9668603-9668674-1
CTCATACCACGCAGCTCTTTTCCAGCGGTCATATTCTGTTCCAATTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAA
+
@CADIICCCBHHBECGDF?AF?EF?F?GH@HH@H?D?GFIFGI.CCID@FF@GI@BAB?GD?DCBFBIIF?DIHAGDCIGI@E?GB?F?HFDE@EEIB@@
@>chr21:9668603-9668674-2
CTCATACCACGCNGCTCTTTTCCAGCGGTCATATTCTGTTCGAGTTTTCTATTCTGAAGAAACNATCCCCAAAACTAGGCAGAGATCGGAAGAGCGAAAA
+
ACGDBFCBD@CD"HAHHAEGEEG?GCD@GIGCBFEIB@GFG,FCD@??BHDEH?GACEFHF?A2FID?IHGBC@FG/EEIG@FFGFIHAA0CCEEFI@CF
@>chr21:9668603-9668674-3
CTCATACCACGCTGCCAAGTTTTGGGGATGGTTTCNTCAGAATAGAAAACTGGAACAGAATATGACCGCTGGAANAGAGCTGAGATCGGAAGAGCGAAAA
+
@EDIAFG?GG?B@AA@GGCEA??ADH@?HA?FDCH2CG@D@?GDA@FB?D@IH@@D?GFA?BDHDBDBIECEBI)BGA@?BBDHEDB?HIAIB@ECAEGF
@>chr21:9668603-9668674-4
CTCATACCACGCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAAGAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAA
+
DGGCDCGG@@H@HBEAABGG@@D??2HGH??IBH@HB@?GC@HHIDEE?GE@?FB5B?FBFGHBEFDBECBCDE@BE@DBCDD?DE?CDF@IDHIBFIIG
@>chr21:9668603-9668674-5
CTCATACCACGCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAA
+
FAGAHA@EEFGGECIGBEH?GF?FHEBAHHA?BIFDB@IE@?DCCGA@HF?A?BIGCBAGE?CAG??F@@E@IAFACD?AFGDE?HEBGEHFHGDH?C?@
@>chr21:9668603-9668674-0
GAAGGTCCTCAGCTCTTTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCNGAAGAGCGAAAAAA
+
CBIAHH?@E@?DDGCGGIHHG@ACHGDBDFCECE@DFDFBI@F?CG?BIE@GDCBI?AGFDBBCFH?B@FE?AD?IICDFDFIED-AECEB@GBIH?GFD
@>chr21:9668603-9668674-1
GAAGGTCCTCAGCTCTTTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAAAA
+
/<CCFDB@HDB?IDFEH@HCEBC?DDIED@?HGEEA@GG?AIHACFHAC@F@HEEGC?A@GCG?HCFC@EFI@ID?B?ADCGCAIEDAC?DG@B?AA?BB
@>chr21:9668603-9668674-2
GAAGGTCCTCAGCTCTTGTCCAGCGGTCACATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAAAA
+
GI??@IGDEGD?H?DBI<EGEEGCG?BG@3G@ADBBGCCFFHGA?BICHAHFBB??IBDH?C@@C?GHBA?@?BIAH?EEFACDFBBFDIEHCG@GIAEF
@>chr21:9668603-9668674-3
GAAGGTCCTCTGCAAAGTTTTGGGGATGGTTTCTTCAGAANAGAAAACTGGAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAAA
+
BBGAH@GD?IGAD2GDDIGADBDAD@ADGHCGBB?HCIAH#GBACIIFDD@CGCH@FBBCIHEHCI@EIEAIC?BACHECFI@CABCBGD?HA?FC@IBA
@>chr21:9668603-9668674-4
GAAGGTCCTCTGCCAAGTTTTGGGGATGGTTTCGTCAGAATAGANAACTGGAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAAA
+
IFADCAEFAFA@IECEEE@GADGIAA?GB?D@@3GI@A@H?H?F6DAIF??FBHECHG@@IDDCAGEF?@EEACIBHHIABCBAEB@IBE?CHBHAHIEB
@>chr21:9668603-9668674-5
GAAGGTCCTCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGNAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAAA
+
CC?CAFBEAIB?BABEHF@HABCI@HHE??HIAD@ECCIF?EA?ECFCCB-@HHA@HABEA?CBGDDAAGFEEFEIICHIADFECFF@?DE@FDICCDA@
@>chr21:9668603-9668674-0
GCGGCGTACAGCTCTTTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATNCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAAAAA
+
H@BDFIC@A?@IDG@IGAAFHI@HCBIC@DGHACCCEIHE@BDCICDBA?EDD?EADGAE@BE/FE?FF@FGGEGHB?GEA?DCE@@AFIE@B@C?IBHC
@>chr21:9668603-9668674-1
GCGGCGTACAGCTCTTTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAAAAA
+
HH@C@FBGIDAACBAEBADBEBAI?BFG@CIFCIIDFBCCHGHDB?@GF@GBB@DAAGG@CDIEABG??FCGGII@BD@AFDE@GBIDFHHFIA@CAE?I
@>chr21:9668603-9668674-2
GCGGCGTACAGCTCTTTTCCAGCGGTCATATTCTGTTCNAGTTTTCTATTCTGAAGAAAACATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAAAAAA
+
HCCCEGB@GI?B?IGCBHI?C?AGFGCHFBCCGDCIHE+AAHCIAGHBCAFGGE@IGA?:B@DGGIDBDA?IIAEIC@GHG?FDGEFFI@GACB@BHD@?
@>chr21:9668603-9668674-3
GCGGCGTACTGCCAAGTNTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAAAA
+
?GAEHHGCH@@A@E@ID3@CHIHH?BBA@AGHBHCA@EA@BDBIEECDEGB@?B?B??EE?AGGDFAHGHE@BCG@?H@AAD@EIGFCBGCAIAEE?EFD
@>chr21:9668603-9668674-4
GCGGCGTACTGCCAAGTTTCGGGGATGGCTTCTTCAGANTAGAAAACTGGAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAAAA
+
HEEI??@?CGBG@GHGE?C;CCHHDABE5DGBGD@EIE!DEB?EE?BBDAD@CHEAFEHBICIBFEBIG@IBDCGDA?C?FG@B@@AFC?EIAGAFIEBC
@>chr21:9668603-9668674-5
GCGGCGTACTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAACAGAATANGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAAAAAA
+
BFBFFI?HAFDHC?@DGED@IEIB@HCBGEEFBFC?ABCIIDH@@AHBHCAIG@DBCE@6GFGAIFC?HGA@EHAB@FAGAEI@GC@DGAIGCC?DGBCE
@>chr21:9668603-9668674-0
TCAGACGGGAATCAGCTCTTTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAA
+
HC?G?GEB<?BCBHHF??CCE@EE@@FDDIDH!BE@BHBIF@?FDEAIGCBHH?BG?AB@@?F@BBFA@CHCHFAFGIBDFFA?DGB?DEIBHABFHB@@
@>chr21:9668603-9668674-1
TCAGACGGTAATCAGCTCATTTCCCGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCCCCAAAACTTGGCAGAGATCGGAAGAGCGAAA
+
@HADBFH?GEAC?BBGGCGECCFH2BIHI@?E@IIHE@@EE@BFHBAACFB@D?@IH@FHAEGAE?DHBG@?DIGGI?F??AGDG?CFIA@DDIEBF@HG
@>chr21:9668603-9668674-2
TCAGACGGTAATCAGCTCATTTCCAGCGGTCATATTCTGTTCCAGTTTTCTATTCTGAAGAAACCATCTCCAAAACTTGGCAGAGATCGGAANAGCGAAA
+
EDFECDHBAH?AAEIEBAAAEH@H@B@GEDHFEHBHCFEGIGDDGIE?H@@CECCFHIFIGGDBIABA)BGADBG?CIEGHEIICIAG??E@<@BFCGFA
@>chr21:9668603-9668674-3
TCAGACGGTAATCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAACAGAATATGACCGCTGGAAATGAGCTGAGATCGGAAGAGCGAAA
+
HF?G?GAFD@EAHIGEAI@BCE@EBEI?DGIDEIDFBGGICH@GIAFBAFIADHDDAFCFBBCF??EAAEIAAGA@ICCHDFAHIEGIFAHIBIA%H?HD
@>chr21:9668603-9668674-4
TCAGACGGTAATCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAACAGAATACGACCGCTGGAAAATAGCTAAGATCGGAAGAGCGAAA
+
CIEGAC@BBEEE?EIB?D?B@DIG?IFDFEGD?HBCDEB@IDFBCFCEA@AABDHGH?AFBF?-ACAAEIAIGC?BC&GDBB)GBCE@@CBGDCIBDAEE
@>chr21:9668603-9668674-5
TCAGACGGTAATCTGCCAAGTTTTGGGGATGGTTTCTTCAGAATAGAAAACTGGAACAGAATATGACCGCTGGAAAAGAGCTGAGATCGGAAGAGCGAAA
+
@I@ACGHI?BEB?GD?DIIIAHHIHFIAI@BD?CAAHC@<@CDIDHBH?EEGEBHFDD@BGC@BFGGDDFFFFD?ACDFIEIHEG@?ADIH?BFC?C?GD
@>chr21:9668671-9668750-0
ACCACTATGTCAGCTTAAAACAACTCNTTATTACTTGTTTTTTGGCTTTGAGAGTCTCGGTGATCAGCTCATCTCACACACAGTTGCAGAGATCGGAAGA
+
DCC?A@F?B?DB@AB@E?CB?BDE7F4?A@CBCBD?@AIIBDBIAGDGFFIFAAB?E(DCFGCEEG?HFAD@IFEGC?@DHDEA?EGDEIFDDC@CBEA?
@>chr21:9668671-9668750-1
ACCACTATGTCAGCTTAAAACAACTCATTATTACTTGTTTTTTGGCTTTGNGAGTCTTGGTGATCAGCTCATCTCACANACAGTTGCAGAGACCGGAAGA
+
FDDEE?CAEEGEBFCADDC?GAH@@AAHI@BFHGFIBC@HEAAHEEC?CB3FCF@GGCAIEDHIBHCGAEDIH?HC@G3CIAB/?CBB?IEH%CDAD?GD
@>chr21:9668671-9668750-2
ACCACTATGTCAGCTTNAAACAACTCATTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGATCAGCTCATCTCACACACAGTTGCAGAGATCGGAAGA
+
?HGIIBEI??DFIHIC(@CCE@GGB@C@?HFCHDH@I@BCFHEFED?CHBGA@CGFC?GBDGGBE@GEHH??GFEGBDGGHABFDEGE?F?BGHI@A@BG
@>chr21:9668671-9668750-3
ACCACTATGTCTGCAACTGTGTGTGAGATGAGCTGATCACCAAGACTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGATCGGAAGA
+
I@E??FDHCGBCBBH?IBBH@FHBIADIH@@HECIBABI?BGA?C@D@ECADFF@AIFHAA?GDBIB?@BGHAEHBAB?GCBHDCHCFBHDBD@HD@EA?
@>chr21:9668671-9668750-4
ACCACTATGTCTGCAACTGTGTGTGAGATGAGCTGANCACCAAGACTCTCAAAGCNAAAAAACAAGTAATNATGAGNTGTTTTAAGCTGAGATCGGAAGA
+
ID?DHCAHG?F?IAIDC?DDGDF@@DDFBCGFCAFG:F@EDHDDFHB@DF7D?BA-GAIDGCH@CIACBB:IBBB?;IHH?@@I@FAHHAGB?3D@EEIB
@>chr21:9668671-9668750-5
ACCACTATGTCTGCAACTGTGTGTGAGATGAGCTGANCACCAAGACTCTCAAAGCCAAAAAACAAGTTATAATGAGTGGTTTTAAGCTGAGATCGGAAGA
+
?I?@BHBEGGHFIGAIBICAFDEAFHGGGGDGAFDB:CADG?HEGIHCBDHIABGD@ABCF@GAHII.@?BCEAHHB0CICGEDFH?IDC@A@H@EAIGD
@>chr21:9668671-9668750-0
CTCATACCACGCAGCTTAAAACAACTCACTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGGTCAGCTCATCTCACACACAGTTGCAGAGATCGGAAG
+
@E@?HHEAH?D?EIGBH?IID@ECEIAD0ACFDE?IADAA@A@DF?CH?IADF?H?CIHC@BGGAHAECFHA?AI@@CCD@CAABCDDHE?IBA?A@BHE
@>chr21:9668671-9668750-1
CTCATACCACGCAGCTTAAAACAACTCATTATTCCTTGTTTTTTGGCTTTGAGAGTCTTGGTGGGCAGCTCATCTCACACACAGTTGCAGAGATCGGAAG
+
HIFFEEBG?A??GAACB?I?B?CGB?@DBFH?E6CGBHCBCIBIBAGDHBFCDC?HAGD@FEFF-AAHAECDHIFHAFIGB?EFDDGBIEIEGFB???CB
@>chr21:9668671-9668750-2
CTCATACCACGCAGCTTAAAACAACTCATTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGGTCAGCTCATCTCACACACAGTTGCAGAGATCGGAAG
+
IAFHHGAEAA?IDAEDDFCDB?I?BGADCC?FFFGABBAE@C?I?CB@IBG@HIEGGEAB@E?CEDDCBBIDGBIDDDCGHDHGDGDDHDCE@ABEDCI?
@>chr21:9668671-9668750-3
CTCATACCACGCTGCAACTGTGTGTGAGATGAGCTGACCACCAAGACTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGATCGGAAG
+
AIADEDDDIFGGABEF@BGBIGF@GDD?EAFDC?GIH@F?BG@?H@D?BA@FGDBCAG?AB@ECIGDIBEEG@HBFEDIBFFHFBDHGIIHFIBAHGFF?
@>chr21:9668671-9668750-4
CTCATACCACGCTGCAACTGTGTGTGAGATGAGCTGACCACCAAGACTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGATCGGAAG
+
@ABF@BDAA@AAH?CHGAE?E@IIHC??FAFCDAG@IHHCECCC@HDEGEFHDEICB@GC?BH?I???BGFFHFGDFEIDDEFEE@AIGH??@@IH?BBC
@>chr21:9668671-9668750-5
CTCATACCACGCTGCAACTGTGTGTGAGATGAGCTGACCACCANGACTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGATCGGAAG
+
@BED?BBEDFIDG@CHHAEH?DFABHEEDCCGEEHDCAE@FI@3FI@I??@IBADI?BHGGD@HCHEAC?C@I@ACE?BEDB?CHFHFB@GFHAABBF@G
@>chr21:9668671-9668750-0
GAAGGGCCTCAGCTTAAAACAACTCATTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGATCGGCTCATCTCACACACAGTTGCAGAGATCGGAAGAG
+
FGCD@$GA@@FHAGCICBHIHGFAFGGC?GHEI?DGE@HF@GIACEGBBADCIGH?GF?BDII@'AFABADHDA?EEHGE?GA@C@CEHBHAH?FIAEDH
@>chr21:9668671-9668750-1
GAAGGTCCTCAGCTTAAAACAACTCATTATTACTTGTTTTTTGGCTTAGAGAGTCTTGGTGATCAGCTCATCTCACACACAGTTGCAGAGATCGGAAGAG
+
B?DCG?GIBEAGCAFBB?GCEHG@HEIGHDDD@@ACIDDH?IAEAH?7FDEBDCBEI@BDEGIEDC?H?AAFHDFHHCFAGBHIAF@C?GCBDDEGFIBG
@>chr21:9668671-9668750-2
GAAGGTCCTCAGCTTAAAACAACCCATTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGATGAGCTCATCTCACACACAGTAGCAGAGATCGGAAGAG
+
CEEEFA@EIGIAFHEAHICG@?@%FBAD@@HBFHDHABAIEFDIGBFDF@CEHACHHDHFEEF9@GG?D@?FHA?BA?BHEEG:AHGC@@A??BEHBBHI
@>chr21:9668671-9668750-3
GAAGGTCCTCTGCAACTGTGTGTGAGATGAGCTGATCACCAAGNCTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGATCGGAAGAG
+
EGFDED@CG?HHHECAI??ICA?D?IBED?BCDD@CEBG?@?I-FCFIH@BEG@ECCEHACBACBGIB??EAHFDGHBHG@IEBHDCAIAGI??GF?HCA
@>chr21:9668671-9668750-4
GAAGGTCCTCTGCAACTGTGTGTGAGATGAGCTGATCACCAAGACTCTCAAAGCCAAAAAACAAGTANTAATGAGTTGTTTTAAGCTGAAATCGGAAGAG
+
ICI@BHBCBDBG@IEFCCAFBEI@E@@GCEGGH@GC@@E?EHCCFF@H0FEFB?DGFFB/GCIHECC9@GEDI@IEH?IIG@C@CGI?C"FA?DDDHAFB
@>chr21:9668671-9668750-5
GAAGGTCCTCTGCAACTGTGTGTGAGATGAGCTGATCACCAAGACTCTCAAAGCCAAAAAATAAGTAATAATGAGTTGTTTTAAGCTGAGATCGGAAGAG
+
IHGAACH@G?CBIBICCI?GF?I@ICBHBBHI?CHACAICAIC@GCB?BF?BHGFBBHGDE#EABEGBCIC@GCGAHBHGDECGG?GAC??DFHBH?FDC
@>chr21:9668671-9668750-0
GCGGCGTACAGCTTAAAACAACTCATTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGATNAGCTCATCTCACACACAGTTGCAGAGATCGGAAGAGC
+
DBHBA?@GAABBDEIGAFDHCIGIEDHED?CFH?IEDGHCHC?FHAABHEFGECEHD@DDDA.FGEIDAABCDHCCDGGHIIBHFB?BHGE@C@HBGE@D
@>chr21:9668671-9668750-1
GCGGNGTACAGCTTAAAACAACTCATTACTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGGTCAGCTCATCTCACACACAGTTGCAGAGATCGGAAGAGC
+
DIHH4CAB?GAHGFG?FH??DGHHAFHC'@DBEBIIA@?DFD@?@DFFDH?AGEG@EFD@IDFECFCFCBIA@EFB?EI@A@DHG@@HIAGHAHHEBAAC
@>chr21:9668671-9668750-2
GCGGCGTACAGCTTAAAACAACTCATTATTACTTGTTTTTTGGCTTTGACAGCCTTGGTGGTCAGCTCATCTCACACACAGTTGCAGAGATCGGAAGAGC
+
BDI@@AA?FC@HCEGD?BGBHA@CIIDBIAHHIG?BF@DCHEFC@BDAA"GE<?GGIBGHCA?FDIBIHHI@IF@I?@ACC?DAFGHBCGDHF@EEB??A
@>chr21:9668671-9668750-3
GCGGCGTACTGCAACTGTGTGTGAGATGAGCTGACCACCAAGACTCTCAAAGCCAAAAAACAAGTAACAATGAGTTGTTTTAAGCTGAGATCGGAAGAGC
+
DFBDAGFEFG?AICCGCEBCI???IHBB??A@GBHGEE@FIH@@E?IEAFIAIEDEAD@GG??EDGA/FGEHDIH@FF@EEB@IGGHBHE@ECEAF@DAH
@>chr21:9668671-9668750-4
GCGACGTCCTGCAACTGTGTGTGAGATGAGCTGATCACCAAGACTCACAAAGCCAAAAAACAAGTAATAAGGAGTTGTTTTAAGCTGAGATCGGAAGAGC
+
GEB=IB@1DAGEBG@@@HCEC?IIHE?GF@CGFEFEBGGIH@GHBF<F?@FAEHEIBCAFFCBC?DDD@E)@C?CAII?@@D@IFC@HB?ADABB@FIDG
@>chr21:9668671-9668750-5
GCGGCGTACTGCAACTGTGTGTGAGATGAGCTGATTACCAAGACTCTCAAAGCCAAAAAACAAGTAATNATGAGTTGTTTTAAGCTGANATCGGCAGAGC
+
ADF@?FECAF@IAIEDDBHEE?CCA@AG@IHFIGI%I?DI?HFAHIH@I@IGC@C@@A@C@HACEEAA'AEGA@@CHFCEDD@E@DDH2IGFH@-@I@@G
@>chr21:9668671-9668750-0
TCAGANGGTAATCAGCTTAANACAACTCATTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGATCAGCTCATCTCACACGCAGTTGCAGAGATCGGAA
+
BFBFG!E?CDG?G@BA@GDB(CDHCDDEA?EFGC?DAAIH@GD??E@EHA?BAGEDG?DDEBEFCB?GECGHBAEFG?ECA+?A?CD?0FEGIC@CBIF@
@>chr21:9668671-9668750-1
TCAGACGGTAATCAGCTTAAAACAACTCATTATTACTTGTTTTTTGGCTTTGAGAGTCTTGGTGATCAGCTCATCTCACACACGGTTGCAGAGATCGGAA
+
@HCDD?AAD@?A?@I@GCBI@HE@HEDDHCEG&FFFAIHH@HHDIHED?GHFDFD?EHD@FHFGHGCH?IF@??FADFEFHGC.G@CBEBAHEAHH@?HI
@>chr21:9668671-9668750-2
TCAGACGGTAATCAGATTAAAACAACTCATTATTATTTGTTTTTTGGCTTTGAGAGTCTTGGTGATCAGCTCANCTCACACACAGTTGCAGAGATCGGAA
+
C@FCECAIHGGFG?I!@EAGGGFDD@BEAEFHAEG;GBGFCAHBDDCIGD@@HHE?HEA@AHIIC?DGIHDCB2CGGEH@@CH?H?AGA?EB/?FHF?CH
@>chr21:9668671-9668750-3
TCAGACGGTAATCTGCAACTGTGTGTGAGGTGAGCTGATCACCAAGACTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGCTCGGAA
+
GFIEEGGCHA?DCHE@EBCG?CCFAIDHI#CC@HGIG@DCHGFGA@ECCGCEFBEEHDEIICIFA?H?HIBGEBD??BFBFHB?@AGCHF@FB+BHB@AB
@>chr21:9668671-9668750-4
TCAGACGGTAATCTGCAACTGTGTGTGAGATGAGCTCATCACCAAGACTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGACCGGAA
+
CCHEBAEEFGBAADFBFD?D@C?DGBBECEG?BIGG!EA@EHFB?HH>GDFAGC@EC@IHEIDHDD@HCEA?HIFEABCFH?IFDDEBFBF@DA+EHA?H
@>chr21:9668671-9668750-5
TCAGACGGTAATCTACAACTGTGTGTGAGATGAGCTGATCACCAAGACTCTCAAAGCCAAAAAACAAGTAATAATGAGTTGTTTTAAGCTGAGATCGGAA
+
AEGH@GD?CECFA@&@CDA@@DDHHI?E@IDFGECIE?HADAEHIEHFDA??HFC?@DHGBICECAHCHFF?IEBFBEEH@EEDEBFD?G?FBBHBC@@?
@>chr21:9671594-9671708-0
ACCACTATGTCTGCAGGGTATGGATAATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAGA
+
IE@BCCDHIDD?I!EGAEGCE-FF?!IC@HIIIG@FCHFHHEBG?IGE@@C@IBCDCBDEFAAEBI?B@CBD?GEF?@C?DF@HAEIIF?DH?BIBCDAC
@>chr21:9671594-9671708-1
ACCACTATGTCTGCAGGGTATAGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCCAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAGA
+
@HB?ACE@@HE@HEIBC?F*AD?CGBCA@BBHEBADHEFCIACICCIBD?IDEF@@FH?F@"BG?EF??ACEBA?ADABB?EADGDHF?F@BDEEFI@FA
@>chr21:9671594-9671708-2
ACCACTATGTCTGCAGGGTATAGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCNAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAACGAGA
+
BB?G@I@?@D@B?HI@GFDBDHEFEADCBDHAFIBED??AADA@BAIDCHDFI?HB@CBEC#CHA@IECICGCCICIFBFAG@A@ECEEADAGBI4FID?
@>chr21:9671594-9671708-3
ACCACTATATCAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACACTTAGAACCTAGACCCCAATTCTACCTGAAAGTAACAG
+
IIAEHDAF!FCFDEEHA??@B?GAECB@GG@CGBCDFFDB@?IHAHGCIFDAF@DH??GHHH!BG@?ABIHCIIDEI?BEDGDDIDADGH?F?@?HAHB@
@>chr21:9671594-9671708-4
ACCACTATGTCAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTGAAAGTAACAG
+
C?HDAFADI?CABA?@?HCGA?IE?CEC?EA@G?HH@GHCGD?@GDCFGGIGDHFAG?BCB@GDF?FDBBEAFAHE@AGCDD??HICFGF?D@AEBHAHC
@>chr21:9671594-9671708-5
ACCACTATGTCAGCAGAGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTGAAAGTAACAG
+
HDICDA?FDAGGDB?'.GIBGIBBGDC@FIHH@.@HEADFABCFDB??AIIF@?BCICE@?BHDEAHGBADHCCIAGCBHEBBHACH@B?FBEEAFEFIA
@>chr21:9671594-9671708-0
CTCATACCNCGCTGCAGGGTATAGATTATGTTATTCTGTTACTTTTAGGNAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAG
+
H@H?CAFE"HGFC???CBIG@@BGBCAHGGECDHDH?ICCGCCI@HCAD7E@GCAIA@BIACBH@HCBHAGD@IGAHBGD@@FDEAHH@GDE??H@CDFG
@>chr21:9671594-9671708-1
CTCATACCACGCTGCAGGGTATAGATTATGTTAGTCTGTTACTTTTAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAG
+
HEF@@H@?IGFI@EH@@EGA?B@GDFEH@GE?D)BI@?@D@G@@BHI@CEDGFDDBCF@DEBD@BEE@HGEDCC@AGIE?@FCDBHCFBDGIGIDCGHG?
@>chr21:9671594-9671708-2
CTCATACCACGCTGCAGAGTATAGATTAGGTTATTCTGTTACTTTTAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAG
+
DBHGEE@ECBE?HIEAD5AD?GHCHIDF#EF?BBBGF@GHE@BACHCHAEIHIBIIFGHGDGFIGFAAG@AFCBIGEHFEAD?DH?B@BGGHEI@CA?ED
@>chr21:9671594-9671708-3
CTCANACCACGCTGCAGTGGTATACCTCTGCTGATTCTCATTCAGAATCTGAACCTAGAAACAATTAGAACCTAGACCCCAATTCTACCTAAAAGTAACA
+
AA?H4FBEGBAI'@??IFC@G+@AEGFAC??I?I?DCDHGFHF@?GEAHDII@A9F??7CCGDA?DEGAIE@DBADE@ABEICEGHG?@IH?B@@0FDEE
@>chr21:9671594-9671708-4
CTCATACCACGCAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGATCTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTAAAAGTAACA
+
IECCHHFFF?G?BIEH?DAAB@CIEAHD@IIE?FGH?A@CBDEGB@@H?BGI$CG@HFHFHG@EF@IBGAIIA?BBCHAHFDEBHHH?IDI@DED@@AC@
@>chr21:9671594-9671708-5
CTCATACCACGCAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTAAAAGTAAGA
+
CDD@EDCBA@H@FBG?DCCE@CFEDDBE@ECHEHCEIDAFHFCF?D@@@GAGB@?CDE?FFD?FCCAGGG@HG@HA?BCFHHHI@AHHAF@@?DHCAB"F
@>chr21:9671594-9671708-0
GAAGGTCCTCTGCAGGGTATGGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAGAA
+
<H?C?FFH@HBFDDGIFHAB0@?FFCHEDA??BEEEBGFABGIBA?ECB?BBGEGC@EH?AHBI?H?AEDIDIB?IAIDCICIG@GF?AIBIDHGEHEG@
@>chr21:9671594-9671708-1
GAAGGTCCTCTGCAGGGTATAGATTATGTTAATCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAGAA
+
?BDBFBDIHGE@GHAIBBFHGEDFE@FAHI@,I@FIIGDGIF@@BCGCF@ICBA(ICDEICF?EIFHHCIAFAEDIDIBGB?FABECGGE?FDDEFC?FI
@>chr21:9671594-9671708-2
GAAGGTCCTCTGCAGGTTATAGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAGAA
+
IFBHDE?B@FG@G?FI6EB@D@I@?IBDDAFEDG@HHBAGGDCAFIFIAFGDB?AD@@FAF?AFGBCIGBHGGDHDEH?I@@IGHIAIG6ABGBIEHIBD
@>chr21:9671594-9671708-3
GAAGGTCCTCAGCAGNGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTGAAAGTAACAGA
+
@@I?BCICGGCEAGA-D@GGFGCCIAB@F@CD@DIIFICE@C?HGIAFHE@@CADBFE@I?FACDGDBIBAHGAHEA@HHECCHDBHDECBEIG@?E?EG
@>chr21:9671594-9671708-4
GAAGGTCCTCAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCAACCTGAAAGTAACAGA
+
DAAG@BGDAD?D?AAGIG?@??GBH@?GHD?BB@IDDAIFBCGHIGC@ECAG??HHIE@ABGFC@HHEG?BBA?CAFIBBAFH$GB@<ECAGABAIEGGB
@>chr21:9671594-9671708-5
GAAGGTCCTCAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAANCAATTAGAAACTAGACCCCAATTCTACCTGAAAGTAACAGA
+
?CIDG?HICB@EABACCBE?IDCGHGDGEF@DE@GCH@@CIBDIFCBFCDIBFECICE&AFGHF?BDA5GEFIEHFHACIIDHIEAE@CHEC?EBCABH?
@>chr21:9671594-9671708-0
GCGGCGTACTGCAGGGTATAGATTATGTTATTCTGTTACTTTCAGGTACAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAGAAT
+
?H@HE?GEHIE?GE@CEAGHFHDEBHDHDGIGAGIHE@HFG?BFAB@A<AE?FF?AGFIGBEFAEH@HHHAFDFE?FHAFEEBHDCB?FCB@FIHGB?@I
@>chr21:9671594-9671708-1
GCGGCGTACTGCAGGGTATAGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTNCTAAGTTCAGATTCTGAATGAGAAT
+
CAIEGH?HF@?DFG?IHH@GHCDGCCEGA@DGIHEBBAGEDAEBDAGCGHBBHEHIGFFFIE@@EECAE@CC?I5BEI@H?A@D?CA?I??DCB?I?I@D
@>chr21:9671594-9671708-2
GCGGCGTACTGCAGGGTATAGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGAGAAT
+
GG@H@D??CH?@D?GACA3@FDCCHE?FBADAC@C?IIIFDIDDGECE@A@CB?GDHI@GEHGICHH@GD?EEDFI@@H?FIIHCB@GDHI@BHBABBBC
@>chr21:9671594-9671708-3
GCGGCGTACAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTNAGAAACAATTAGAACCTAGACCCCAATTCTACCTGGAAGTAACAGAA
+
E?B@CI@ADFH?IBHGEABGFECA@@CEFHFHCGI?BH?ABDBCF@???C@I=HACE@@?BFBGBHF@BIGBEDBIGFB?@GI?AHI@,EEFE?GH5DA@
@>chr21:9671594-9671708-4
GCGGCGTACAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTGAAAGTAACAGAA
+
?ECCIABDBE?ABDE?EIBAGAID?AI@HFBHADCC@GAFI@@@A@HFCH@C?HBACHBDFEEIIFCCHIBAH@EG@EICACAIB?AEAA?BB?BFGI@D
@>chr21:9671594-9671708-5
GCGGCGTACAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTGAAAGTAACNGAA
+
@GBAGIFC@?G??@BDFHDEAIEFC@II?!HIGF@CDFGB?ICC@?IH@EFCDBB@?@ABF.I@G@@D@DHD?IHHICIBABDE?IDGBE?GAE@@2FAA
@>chr21:9671594-9671708-0
TCAGACGGTAATCTGCAAGGTATAGATTATGTTATTCTGTTACTTTAAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGAATGA
+
B?ABAEE@AEBDGID?G1HDGGHDA?FHCIBH?CE??EECHHG?EB2CBBHAEAADGIDACBHEB?AHGD@IIG@FHBCGDCEHAAIBA@EBBCGEEAIE
@>chr21:9671594-9671708-1
TCAGACGGTAATCTGCAGGGTATAGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCAAAGTTCAGATTCTGAATGA
+
GFEB?EGEG@HH?H?ECGCFBGBCGGECEIBB@?BHC?@F?EDBACI@IEHB@FIFAGFEFIFCHABFGD@BIHB@GBDB-IFFBECC@EIC@@IFF?@A
@>chr21:9671594-9671708-2
TCAGACGGTAATCTGCAGGGTACAGATTATGTTATTCTGTTACTTTCAGGTAGAATTGGGGTCTAGGTTCTAATTGTTTCTAAGTTCAGATTCTGATTGA
+
@ACEFH?C?@FEHFI@F??C@I+GICGBGE?C?FHGHFHIECHHCG@BD@@@FDBFBCIIFBDECDBHBGB??DIHIACIID@E?EEGGGAE@H??=A@?
@>chr21:9671594-9671708-3
TCAGACGGTAATCAGCAGTCGTCTACCTCTCCTGAGTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTGAAAGTAAC
+
IFBCBIGCBADCGFBH?HE1CAEGF@FIBI6BAHI'GF@?AEE@IHB@?HCEH?FG?I@DGCIBDF??EHEEACBBIAG??AHGB?AGAGDGBCCGIEEG
@>chr21:9671594-9671708-4
TCAGACGGTAATCAGCAGTGGTCTACCTCTGCTGATTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCTACCTAAAAGTAAC
+
@CEI-ECBAA?D?@DDE@BCHBCCGBAH@?BBDG?IB?GFEF?IADIIGDD@@A?@HHHHFBHCBGDGBGH@E@@HBH?IFF?AHEHGBD?G?AAAECFC
@>chr21:9671594-9671708-5
TCAGACGGTAATCAGCAGTGGTCTACCTCTGCTGCTTCTCATTCAGAATCTGAACTTAGAAACAATTAGAACCTAGACCCCAATTCGACCTAAAAGTAAC
+
D@IBBCFHCHAHCIFAFAHDBCGFCHBDE?D@G@1F@E@AFAACCGGFI?A?DA?HGDBHBID?@CFAIHIGHEIAC@CBHHAAAD#GEDEGFAE@C@@D
@>chr21:9675322-9675387-0
ACCACTATGTCAGCTATAAGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTCTTAATTAAAGCATCTGCANAGATCGGAAGAGCGAAAAAAAAATA
+
B@FEHGAEH?@EAGE@CCGAB@HGHCBECBE?BD@HF?@@FHCAIEB?IGCED@D#HA@ADD:C@BAGHGACI@!DIGBEB?HHFCH@DDHCEDGI?C6F
@>chr21:9675322-9675387-1
ACCANTATGTCAGCTATAAGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
F?C?/GI@DA?A1ECA@?@AGEEDEFGEC@AC@F?CED@@@GIACDBAC@?CABDEA@DCIG@HBHIFGHIFG@C?GIFCDF@?ED@CEEA@AHFCC@FD
@>chr21:9675322-9675387-2
ACCACTATGTCAGCTATAAGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGNGCGAAAAAAAAAAA
+
?GI?@@AC@E?GGECD@D?EHEAHCGIHGC@@ACBBHF@EIDBFEGHIHEBGGHHBBB?IBCHFEHH?AIF@BFFGHEFHHGHEH!FFBEHHHIH@EIAG
@>chr21:9675322-9675387-3
ACCACTATGTCTGCAGANGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCTTATAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
FDDFCGC@ABDGEE@D@8CIIC?ECIHHIG/ED?GIEBF@B@GIAHB@F@CGHGB@GGE@GGGE@BAH?B@DII?EC?I@?FCB@FID@CCCE@AIBFH?
@>chr21:9675322-9675387-4
ACCACTATGTCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCTTATAGCTGAGATCGTAAGAGCGAAAAAAAAAAA
+
BEF@?C@HAHDAIFCICF@C@GFFBEBC@CHAGC@IDBF?D?@BFHI@HCD@EHICD@?@C@EHADFHBGGICFBD??IB?5E?D@CAIIE@BDDHID?G
@>chr21:9675322-9675387-5
ACCACTATGTCTGCAGATGCTAAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCTTATAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
IH?HCI?@?I@CGCH?C@GGI'FDHHEGAI?@@FHBE?B?@?B?ABA@A@CG@CFAGHF@?BHGFFBDFED@EFA@HFIDGBFDHHHHDF?BBGI@HD?I
@>chr21:9675322-9675387-0
CTCATACCACGCAGCTATAGGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGTTCAGAAGANCGAAAAAAAAAA
+
DA?GDB@@DE@GHFHFFBAA@GGEIHFIFH@AEEHF*CBD@I?D@@BABFG@@IE@HGCCDBG@BCFAH@A@IFF@DI2CH5I??DC=BGGDHC?@@@FE
@>chr21:9675322-9675387-1
CTCATACCACGCAGCTATAGGCTTCCCTTTAGCAAGGGTTTGATATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
GIDGBDIDCD@IDDD?GEIHBGFA@GHDFDCAIBB?FD@BIDE9??FE?IC@@BDACFAABIGFAIEEAFG@EBF?HDGBEHFBEE?@HDCF?DF@@E??
@>chr21:9675322-9675387-2
CTCATACCACGCAGCTATAGGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGGGATCGGANGAGCGAAAAAAAAAA
+
IID??IC?EGBA?CGB@B?ADI@?GICCHFFCBGCGH?H@C?BCIIDBEGHFFAAEFBAHFIH<D@CBEI?HEGHA3GHBDEFG)BBCFFDBH@BH@E@C
@>chr21:9675322-9675387-3
CTCATACCACGCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCCTATAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
I?AIIECGHHIIGGCIAHFA@FF@@BECEBDAEBHDCEAD?ICCF?HGDHHC@FFCHHBIB@@CI?BIHH@DDI@@@EI@@HDBBEGIA@CDICHHBCDH
@>chr21:9675322-9675387-4
CTCATACCACGCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGAGAAGCCTATAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
BB?DDA@C@FBCAFFBFAIG@FHF@BBEIFAABGD?GBAFGGDHEDG?HE@F??@GAHAB?&BC?HGCGAAICAFHCHAFDGECGBAGIBC?GGIFEHD@
@>chr21:9675322-9675387-5
CTCATACCACGCTGCAGATACTTAAATTAAAAAGAAGAAAGATCTCANACCCTTGCTAAAGGGAAGCCTATAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
CG@@?DCGBIEA?F@?BEH6FBFGB@ID@CF@ADDBGHHFCC?BDF?9FCA??BEFI??GEECHIACHFCEDCIFFHAABFAAHEDADFI@GDEB?AC@B
@>chr21:9675322-9675387-0
GAAGGTCCTCAGCTATAGGCTTCCCTTTAGCAAGCGTTTGAGATCTTTCTTCTTTTTAATTTAAGCTTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
FIDDHHHCBCGG?@D?AFDF@FE?GC?@DAHEFH#GC?EBHIHIBCCBFF?FH@DH?IGGCB@GFH/BAIF@AC?HG@F??G@@FAEEA@FCEDBHGD??
@>chr21:9675322-9675387-1
GAAGGTCCTCAGCTATAGGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
??CGFFHDDIEGIDBAC@CAAHFBGFCHDI@HFHDDIICGDHFDBD?CEFADBE?BBBBCCCG@IHHCC??ACB@?AICBIFDI?GCHCADF?FBFFIBC
@>chr21:9675322-9675387-2
GAAGGTCCTCAGCTATAGGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCNGAAGAGCGAAAAAAAAAAAA
+
ED@?EI?CA?BAAF@GC@@CAG?CD@GCGGHCBA?@@GA?IECCHDED?GAD?EDEGGHGGACCADB??E?IIAFHF@D0A?GDE?EDIFFCDEDGDGAB
@>chr21:9675322-9675387-3
GAAGGTCCTCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCCTATAGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
HC?@H@EHIHIBHCA?CIIDGCG?HBCA@?DFEECFHFIG?BED?A@FAE?@ABD?GADF?AH@BDB@CBDC@CICAAIH?I?DIDFAGCF?BAFBGEAH
@>chr21:9675322-9675387-4
GAAGGTCCTCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCACACCCTTGCTAAAGGGAAGCCTATAGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
GB?@A?HBGGDFIDDEE?F?HCBIAAEACICEIAHH@HCAHHHHB$FHBIGCE@DIEAHDHA@GB?ABAEEEIGDBHGHGH?IHGGAGGBEBBHCDCIBA
@>chr21:9675322-9675387-5
GAAGGTCCTCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCCTATAGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
A??BA?AB?BFE@H?C?GHEFABCF@BA?A@F?BHHFBAF?DGCAD?DCHADC@@I@@CCDHHHIABEAE@G?DBGIH?BED?IHAGFAB@B)BGAIBGH
@>chr21:9675322-9675387-0
GCGGCGTACAGCTATAAGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAGTTTATGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
HI@ADBI@C@CFGC?F@IHAF@BICIGEAE@EGFHG@GCFAEDC?@@E@IECADEAC#B@EB2GE@H?IBGB?C@IH?D?HCEC@@F@D@@GBECIH?HI
@>chr21:9675322-9675387-1
GCGGCGTACAGCTATAAGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATNTAAGCATCTGCACAGATCGGAAGAGCGANAAAAAAAAAAA
+
BDIB?FBAA@EIIGEDG?BC?G@FIHIF@@CCAFB@GHCBC?GFH?EDGCG?AFEI@E@>DBA@?H?BEBED'CAD@AIGIACFHGF@-GIEI?HEG?DB
@>chr21:9675322-9675387-2
GCGGCGTACAGCTATAAGCTTCCCTTTCGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
HCCDFIH?HCIEFBEFAEGB??H@G@B+IDHGGCBHDAB@EFII?IAEH?EBGE??GAFHD@BIDBF?AE??AIIIDEDIEABGHF?CFEA@EHEHIC@B
@>chr21:9675322-9675387-3
GCGGCGTACTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCTTATAGCTGAGATCGGAAGAGCGNAAAAAAAAAAAA
+
@ECF@DDII?IFGCICEDI@@IG?D?@?HHG@?ABFA?FEHEE?HACCAHH@BCABH@@AIHGGBCBAA?IEBHCAC@DEIIFGE@E3?B??CCAG?ACH
@>chr21:9675322-9675387-4
GCGGCGTACTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCTTATAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
A@FEDC@CCBICI?BBDFF@EHFH@IF@@FBEGDI@?FD@?AEICA@HBI@DCIEG@FGAGH@FGGDGB@BHDFHABACID??HDCC?HFAFCEEIDIGF
@>chr21:9675322-9675387-5
GCGGCGTACTGCAGACGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCTTATAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
B@?FABEAG@GD?I@=@DDDCFDCEA?EGDDABCHDCICFD@IHBED?EBFDIHBCHBCDEB@FA@EGFE?AIHGHBDA?HI??IIFCE@IAH?@H?GDF
@>chr21:9675322-9675387-0
TCAGACGGTAATCAGCTATAGGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAA
+
?E?AG@BEFC?EEGC?DGA?AHF@?HFGDG@BE?EHCCGD?FDA?EFEI@EHEGDGB@H@FEFC?CHIGCI?AHBDCEF?A@DEBCI?FIFDAFFECCDE
@>chr21:9675322-9675387-1
TCAGANGGTAATCNGCTATAAACTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAA
+
HDAGC#IFA@GBF-B@BBBH?>FI??GAHGE?ID@CHHFF?ECG?BG?@?GDBAFIA@HEIDIE?HDH@HAEII?FFGFA?DAHE?GGA@AG@@EE?HCF
@>chr21:9675322-9675387-2
TCAGACGGTAATCAGCTATAAGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAANAAAA
+
E@@FGBHECC@AFFGEHGI?I?@@BD@FEA?AH@?HCAAEEAHCEIAFIEBH@@ID?BCGBHF?@GGB@HBAIE?F@?CGBCHGGDGEB?BGAAI0CAGE
@>chr21:9675322-9675387-3
TCAGACGGTAATCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCTTATAGCTGAGATCGGGAGAGGGAAAAAAAAA
+
AF@FE@BGCEG?AI?IEFABB@EDFCCGHIIHB@?BHBA@C?HDG@C?CABD?HBGCFFFD??BADD?@HEEBIE<@DBCI@EF$GDIB$?HIIACICFG
@>chr21:9675322-9675387-4
TCAGACGGTAATCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCTTGCTAAAGGGAAGCCTATAGCTGAGATCGGAAGAGCGAAATAAAAA
+
@CH?B?IFAEB?G@@CFDFFFFDDF?G@DHACD?EHHB/CFEGDB@IGHA?HIBIHDAIAEGHCEB@G?I@FB?A?BDCB@IE?ACBHEIDE?C1HAD?F
@>chr21:9675322-9675387-5
TCAGACGGTAATCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCTAACCCTTGCTAAAGGGAAGCCTATAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
IGEDDGA@FDHEEI@CIBECEGHFC??DC@HH@DDC?CDIF@@EA?C0DBGEIBBIHBA?IECCHIAHDCF?@@CA@?GFFA?EC?DC@@IE@@IICF@?
@>chr21:9675384-9675449-0
ACCACTATGTCAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
IHCCIB?B@ECEEIIICEBFI?FIAABFBDIH?FIIHCFCDFHIDF?CHEBB?IEI?GCIACEFCABC@A?BEI9@?@EB?@FHFEGAAGH?B@BFGCBB
@>chr21:9675384-9675449-1
ACCACTATGTCAGCTGTAAGCTTCCCTTTAGCAAGGGTTTGAGATCCTTCTTCTTTTTAATTTATGGATCTGCAGAGATCGGNAGAGCGATAAAAAAAAA
+
?B@AGAAH@EGIBBDGFAFAE?GEIIBDGCAAH>GDGHFIFHAHHG"FC@IE?@IIADFD?GDH)E@I?EIA?@DI?@BAAB-?DCBDIE1?HG?@BI?G
@>chr21:9675384-9675449-2
ACCACTATGTCAGCTGTAAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
@ECIGE??EF?HGBIBFGEC@ADCFFDHEABGB@)@F@F?BIBCHIGCGCHFDIHFFAHHCDC?BHEEGDHDHDHCIGDEGCCFDDCHGHF@CDG?HFH?
@>chr21:9675384-9675449-3
ACCACTATGTCTGCAGATCCTTAAATTAACAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
?GAFBBHHDECHBEHDB?DCH???GI?CG2GAE?GDEDHF@,?DI@DFIBE@GE?HEH@HBCB?A@EAFG@EH7CFE@@@G@FDGABEIC@HHHDC?D?@
@>chr21:9675384-9675449-4
ACCACTATGTCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTGACAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
DGDGIHEH?IAIGEEFGDBCFBFDHI@GGG@@GGIDAHI@CFFEG?B?EIAFD@??E??ACDIGBAG@GDDCBDEH@CFAAHIBC@HFE@EBIBAAEBHF
@>chr21:9675384-9675449-5
ACCACCATGTCTGCAGATCCTTAAATTAAAAAGAGGAAAGATCTCAAACCCGTGCTGAAGGGAAGCTGACAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
C@FEE9HIBG@?CHB?GEGCC?ADAFHHCDC@AC#AABFCI?IHII@?DEAIF?DD5HBHFBCAGIEC?GCHEBA@GEAHHHED?H@H@D?EAGCCEGB@
@>chr21:9675384-9675449-0
CTCATACCACGCAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
CA@ADDHGBF?BA?GGIC?HHDC@?EGCDABCFI@FB?C@EA?ECC?@CIDE@?FCA?2@?GF?HB@E@GAGHCFBGIEGGG@IDHC@BFB?HAHGAHFI
@>chr21:9675384-9675449-1
CTCATACCACGCAGCTGTCAACTTCCCNTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCGGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
AGIB@CDHCFFH?IBCI@IE3F@EHDG1?AIA@AB?@E?IG?CIGA?I?CGHD@BGEG?F@IGIHH@CC?I'DEEG?FF@F@BBICADDCFACEGABF@D
@>chr21:9675384-9675449-2
CTCATACCACGCAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
BB?DEBAEFE?EDAHCCI@?E@@HEBFFC@D?GEHG?DDHBIAECFDHGGHG?A3GIB?IIEDCGEG?AFE,DCGIFHHF@BCIICGF@A?DAHBGAG@I
@>chr21:9675384-9675449-3
CTCATACAACGCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTTAAGGGAAGCTGAGAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
??CCHAI0DBFBHFDFGGHBCEGFBF?AI?IEA?GG@CIHBC??@HF?IEEBGBIDE%CEF?FGC@E?@E3IDBIEFEEBDB@BFDGDFICIG@DD@IDC
@>chr21:9675384-9675449-4
CTCATACCACGCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTGACAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
@H@GGGBEFAI@@G@DIBCADDIGBA?ECDEEI?GEBA@F?DGFAG@FBFAICH?DBEGIBHDFHAH@FD?HB?@DHFIEGGGD@CHGHBI@CIBAEFE?
@>chr21:9675384-9675449-5
CTCATACCACGCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTACAGGGAAGCTGACAGCTGACATCGGAAGAGCGAAAAAAAAAA
+
AHBFBAEHIHEHFG@DBBAAA?@AEB@DFB@DE@?GHIABH?FIHDEFCD?AGCBFF@$G?@DBDEA?AAGI??BHA2EBA@DHFC?F@ICF@HAC@EHI
@>chr21:9675384-9675449-0
GAAGGTCCTCAGCTCTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
@A@DGAICABCGEB.@@IDDGAAEGGGACFBHBGD@EADAIEHIB@IFH?H@ABGG@BAC??HABGI?AHEDCDCE@F@@@CEGFDGGGAAAIH??@@GB
@>chr21:9675384-9675449-1
GAAGGTCCTCAGCTGTCAGCTTCCCCTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGANCGAAAAAAAAAAAA
+
FB??BB?DBGCHC@D@ADBDGBBGD-GIIEHBFGIGAH@?@H@HFDG@HFGDFFAEDGDDFHD@HIGGECFAG@DB.BEIACDIE<A?FAI@HIAG?DD?
@>chr21:9675384-9675449-2
GAAGGTCCTCAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGGAGAACGAAAAAAAAAAAA
+
BI?EDCFB@CBAAIA@GGDBFDBE?DIAFFAEHIHACDIIBDE?@CHH@AIE@HB?@DAEBIHD@DAFIHA@E@HFAAHFE2B@A.EHB?DF??@FFDII
@>chr21:9675384-9675449-3
GAAGGTCCTCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTGACNGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
H?HH@A?GGH%EAI?GBIICABG@FFECFCFA?HBEBEHBCBH?FHBBA?BCHEHHA9H@C?EB?AFAC:?FDBGD@BDCB@A?ICCIDHGHAEBBDDG@
@>chr21:9675384-9675449-4
GAAGGTCCTCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTGACAGCTGAGATCGGAAGAGCGAAGAAAAAAAAA
+
?ICEF@AED@??ABD?GEIAIC?E??D??FBC@HAI@I@?EGEGBC?@BBGDI?FBCIH@?DFE?DIC@CIBBHIC@AF@FCFI@EFHBD+C@GH@IHC@
@>chr21:9675384-9675449-5
GAAGGTCCTCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTGACAGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
IA?CHAF?H?GG@GBBHFBBE@FEHCABAIHHGHCAB?HC@ECEIHICBH?F?BACHCDA@IGHBG?HD@?FHAGBDE@F?HDFCE@GCFDAIDEFFDF?
@>chr21:9675384-9675449-0
GCGGCATACAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGGTCGGAAGAGCGAAAAAAAAAAAAA
+
?@HBG=DFIAACB@?HHCD@EIDG@BG@FBFAEAECGIDFEEA?A@?@@G@HCEG@F@DHG?EH@8@G@B?I@BH&HIHBCFBHDDHDAAIFG@@?ICCI
@>chr21:9675384-9675449-1
GCGGCGTACAGCNGTAAGCTTCCCTTTAGCACGGGTTTAAGATCNTTCTTCTTTTTAATATAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
IAECEFEFG?DH.CDE?FCEFF@?CHCI@DCEHBCHGH8@ID@E$BCAIBF?FHD@AEI-BBGGBFHIDGC@DBDAE@FFHF@HCGFH?E@AGGIGIF@I
@>chr21:9675384-9675449-2
GCGGCGTACAGCTGTNAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
HADCACE?DACHE@A1EGFBH@GC@AAGE@ADCEDGHHIIFGEBC?DCEGHEE@HGHCECBG@EBFDDFEDIEHHEFFGDBHAHI?FHAECAI@@BDAHD
@>chr21:9675384-9675449-3
GCGGCGTACTGCAGATCCTTAAATTAAAAAGANGAAAGATNTCAAACACGTGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
ADEGBBAADHF?FA?HBC?D@EGDHBH?FD?@*?EHIGGG=FADA?E/?HAFD@ICCDIE?HIFDFFICFEABIAFA@HFHFDAHH?GE?AC@?IDHIDD
@>chr21:9675384-9675449-4
GCGGCGAACTGCAGATACTTAAATCAAAAATAAGAAAGATCTCAAACACGTGCTAAAGGGANGCTGACAGCTGAGATCGGAAGAGCGAAAAAAAAAACAA
+
AD@G?I0BACECEDE?2FDAGIGB<I?C@@4??HEGFGCAD@FG?DI+E@GFHBFHEDCHE&??EI?F?B?A?FG@C@DBG@FGBAGDAHGFCBFHC!I@
@>chr21:9675384-9675449-5
GCGGCGTACTGCAGATCCTTAAATTAAAAAGGAGAAAGATCTCAAAACCGTGCTAAAGGGAAGCTGACAGGTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
EEFAIHBEFBAAD?C??CAGCEF?BGBEIBF9HCGIDBH@EHEEFG=EIDBIAECHFHEH@DCGEGHDBD,E@EFCCAFHDC@BF@AHBBAGF@FIBAAD
@>chr21:9675384-9675449-0
TCAGACGGTAATCAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGAGAAAAAAAAA
+
GHA@G?FDE$C?@G@ICBHIA?HGBEDD?FFE@DAHH@?DEAHD@IE?DG@?BHAD?EB@GIFCEGDFCHDBD@IECGAE@EBCACBAI,GFIEIADBDA
@>chr21:9675384-9675449-1
TCAGACGGTAATCAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAA
+
BHADE??FHDGHB?@I@BABEGG?BGIACEHB@I?DIHFCGHDFDD@@?DDCBAC@CB?EFBBEEGFHDHGG?FB@CCCG?AHEIGACEGAB@EA@FICG
@>chr21:9675384-9675449-2
TCAGACGGTAATCAGCTGTCAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGGATCTGCAGAGATCGGAAGAGCGAAAAAAAAA
+
CE@H@?EDIG?HGB@DGDGIHEBCEEFAI?FCHFE@I@IDAI??IEBEIDH?AF@FEGBCHCBGHCE?H@DE@CGBHFBEEFIAEC?@FEACHHI@AIGG
@>chr21:9675384-9675449-3
TCAGACGGTAATCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGATAAAGGGAAGCTGACAGCTGAGATCGGAAGAGCGAAAAAAAAG
+
HC@E?BF@HAFI@DFBCHFFDCEFHB?A?DBE?AFABC@GGBFHACBDG@ACCCDA1BHECIDAGICEC?ADEAIIE@IIBHGACCBGABC@HIGC?@I=
@>chr21:9675384-9675449-4
TCAGACGGTAATCTGCAGATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTGACAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
?B?@FCH@C@AG?@IHC?HECA?CD@BC?IDDBF?@AFBAIEGGAHC@DC@BADCGBEAGDF@GFFHFI?D?BGAIEFBDIGFDIIA@FHGFID?EDCBI
@>chr21:9675384-9675449-5
TCAGACGGTAATCTGCANATCCTTAAATTAAAAAGAAGAAAGATCTCAAACCCGTGCTAAAGGGAAGCTGACAGCTGAGANCGGAAGAGCGAAAAAAAAA
+
HF?AC??EFDIFIHGCE3AEIGB@A?HIHDDAHIFDFADAH@HGEBDBAB@@B?H?B@HH?D??DC@@EFF?HIBGFBAG/FI?HHAHHDADBBCIDIA@
@>chr21:9675446-9675511-0
ACCACTATGTCAGCTGGAAGCTTCCCTTTAGCATGGGTTTGAGATCTTTCTTCNCTTTAATTTTAGCATCTGCAGAGATCGGAAGAGCGGAAAATAAAAA
+
CDI@D?ABCE?F??CH%ACCDEIIDDAGEDFD@IIFGHGAD?F??BE@GFCE@+"GBCABH@@8@@BBEG@IIFCD@H@G@DIG@DHAA%CIBD)DF?2@
@>chr21:9675446-9675511-1
ACCACTATGTCAGCTGTAAGCTTCCCTTTAGCATGGATCTAAGATCTTTCTTCGTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
F?BBF?EFHEHGBAG@BFAG@I@FFHAGGFFBA?GD&?$D#G?GBBHCA@E@E>D?DB@BGBCDEB?EHDCEGI?HFF??CHBIB@A?IHBCFDFHCGIF
@>chr21:9675446-9675511-2
ACCACTATGTCAGCTGTAAGCTTCCCTTTAACATGGGTTTGATATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
FE@DHEFDBDBGBHHFCG@A@DB@DDDBGE9FBIB?GEDIHB*AGEE?CBDHE@FEDECEEDGEFGIIA@EIIAFBAFFBG@AD?EC??@@@FIDDEG?B
@>chr21:9675446-9675511-3
ACCACTATGTATGCAGATGCTTAAATTAAAAAGANGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
CFEDDGHGEF7HHBBE?GGCIIIADFCFHBGIDD9BII@GGIEAIGEBEIBGACIAFH;FD@F?IFIEDIGCDBHFIEIHFHA@CHEEFDGAGD?H@BDH
@>chr21:9675446-9675511-4
ACCACTATGTCTGCAGATGCTTACATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
EHEHDDAIG@FFBA?E?IIIGCA)EHDFBDA@B@IAHAB@@FFABFCBHB@IGCEEFB?CGEA@?DIBI?AI?G?@?EDCAHAB?GIA??@@BBEGIGBF
@>chr21:9675446-9675511-5
ACCACTATGTCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGANCGAAAAAAAAAAA
+
IC?@AEIFH@GCC@E?G?ICI?IE?H@?DDCBG@IEGGFFB?AH?@HGDDDGBAEEC@EE?GAGA?@AB?GA@EAF@GBCA?C?FF"BB@HDFB?I?BIC
@>chr21:9675446-9675511-0
CTCATAACACGCAGCTGTAAGCTTCCCTTTAGCAAGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCTTCTTCAGAGATCGGAAGAGCGAAAAAAAAAA
+
BGGGIA>IFIGDD?BCBIFI@?HDAIDCFBFIDG1H@AGBCBCI?ED?FBAIDG@C@BA=I?DCADCA-EHAGEHG?FE?IHAE?F?A@ECF?ADB@CH@
@>chr21:9675446-9675511-1
CTCATACCACGCAGCTGTAAGCTTCGCTTTAGCATGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTTCAGAGATCGGAAGAGCGAAAAAAAAAA
+
?EEEHI@HD?H@C?EAG@DB?CAHE!FDHEBHBDHF?FGFICGACBIHD@CAAEGHFIBAD@?GFHIBBBCGA?GEDHECE?E@@DEBEHC?AI@GCDDF
@>chr21:9675446-9675511-2
CTCATACCACGCAGCTGTAAGCTTCCCTTTAGCATGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTTCAGAGATCGGAAGAGCGAAAAAAAAAA
+
?DIBA?DDHFCDIDAG@I@AFIHBEI@CHA@A?EDAAHAIHEICDIH@@FB@FBFBFDGG@GBIBIEGGGFI??@IA?FEDIBI?H?GCGA?CDB?FCHD
@>chr21:9675446-9675511-3
CTCATACCATGCTGAAGATGCTTAAATTAAAAAGAATAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGACATCGGAAGAGCGAAAAAAAAAA
+
HDH@@BDCD<FG?AFEIF?HECCDGEFEBEEICHDD=AIACEEFCFHAFICC?ECGE@@CDCDEEFDBBDDEDIGBH9GIFFGDDBB@@A?HIC?@CAGG
@>chr21:9675446-9675511-4
CTCATACCACGCTGAAGATGCTTAGATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCNGAAGAGCGAAAAAAAAAA
+
@CAEEDFIHA@GDAID??BGI?G@%CA?BFFG?AGFBI@CG@EII@B@BHICAGEFB@@HFE?GDCCIDAFB@EB?HDAEA3DCGF@EEBID?A??D?IA
@>chr21:9675446-9675511-5
CGCATACCACGCTGAAGTTGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAC
+
A9ABGIDHFEGDC@BBE=BAIFGDC@GEI?@EHFDFBACHGDDHAAIGAI@@BEIH?BEA?B?ECIEDI@FBGHEEFEFE?AF@FDCEC?CCIIDHFC?5
@>chr21:9675446-9675511-0
GAAGGTCCTCAGCTGTAAGCTTCCCTTTAGCACGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTTCAGAGANCGGAAGAGCGAAAAAAAAAAAA
+
EHGDHEDH?@AI?DHEECBCG?HIAIGEGIIF"@BHEFIFFIIBHBDDFB@@IFAACCE@@CGA?FGBA?IAAF?EI(FDGDFDB?G?DB@CEIHIDHAH
@>chr21:9675446-9675511-1
GAAGGTCCTCAGCTGTAAGCTTCCCTTTAGCATGGGTTTGAGNTCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGAGAAAAAAAAAAAA
+
CFGGEBDABFIGE@DHDDIGB?HEFI@EBCBCAIC@F?@EHC-BHEAFDEG?B?AEEAHHIBDFHBFFIBFF?AEIE?G&BIIG?I*FGBD@GCFCCFID
@>chr21:9675446-9675511-2
GAAAGTCCTCAGCTGTAAGCTTCCCTTTAGCAGGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
BHD4IC?I.C?IF@@ABAAAHEGAG?GHCE?F"FBDDAGH?IGGCIBI?FBEDIGD?BBIIA?AGGAHC@GEA@CEIFGGB?ADAD@D?IF?HEICBED@
@>chr21:9675446-9675511-3
GAAGGTCCTCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATACTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
AB?I@DDE?GDB@DBHE?GFFH@@IFEFG@GGD@AE?G@EHEIEB?F?A@DA,CF?C?B@DEEBICGDEHB@A@CAEHGAIIDCBIC?BDDAFG@DHCHH
@>chr21:9675446-9675511-4
GAAGGTCCTCTGATGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
HHGE@BIH?AI?B5FEIIIBHGB@EAB?I?BIIHHD@EEEFEBBIG@GH@@DIHB@GCBBA?BIEHGEII?IG?EFBDABICIGDAI@??BAEDGHEAF?
@>chr21:9675446-9675511-5
GAAGGTCCTCTGAAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAATAAAAAAAA
+
GBI@AH?HG@AA@?ACFE@?I@ABHFBCIHGGGE@@A@FDFG@FDGAGF?BDFDGDEIBE?HDG@BHHAFBBD?HBD?DBHHDGB?@CACC=HIDAH?FI
@>chr21:9675446-9675511-0
GCGGCGTACAGCTGTTAGCTTCCCTTTAGCATGGGTATGAGATCTTTCTTCTTTTTGATTTAAGCATCTGCAGAGATCGGAAGAGTGAAAAAAAAAAAAA
+
FH@E??GAGGDDD@C;GCFF??F@@@GEF@I@AC@D.BCCAGGBIHB?@??ABB@C;BFGDCECCDAFEFGHIGGI?C@A?CG@I6ABA@IFEBD@FDHE
@>chr21:9675446-9675511-1
GCGGCGTACAGCTGTAAGCTTCCCTTTAGCATGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
FFIHCBC?BGAH@EBEA@ACCF@E?DEG@?D@AHCD?FEAGBCHBBDAC?C????DECBAIFE@@FIFCGEEGGHECA@@G@CDBCAIH?F?CHE?GEAG
@>chr21:9675446-9675511-2
GCGGCGTACAGCTGTAAGCTTCCCTTTAGCATGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCATCTGCAGAGATCGNAAGAGCGAAAAAAAAAAAAA
+
BCII@HGAF@H?HBIC??DIE?BICCI@D@EDBGH@G?IGI?EFDDB@BFF@ICAEBGH@DAA@FIGEEDFCCGGHFIA.CBEFECI@EDADABEABIB?
@>chr21:9675446-9675511-3
GGGGCGTACTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGATATCGGAAGAGCGAAAAAAAAAAAAA
+
H/CGHCDEAIIH@?GFDGCGCHEICDC@C@CIBCCDAA?EAI?G?F@DDF?G?HGF@F@<F?FGDGI?DDDFFE3?CBF?EEHHG?GEFFA?GGHCGEIE
@>chr21:9675446-9675511-4
GCGGCGTACTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGGGCGAAAAAAACAAAAA
+
I@AA?F?BHFFGFHBAHCIBDCHBA@@BBD?GGBA?DCIG@?DGIEGGAFGA@H:CCBFH@IAEFED@?AG@CAGHHC@FB@G!@CG?FBBGB?-@@GIF
@>chr21:9675446-9675511-5
GCGGCGTACTGCAGATGCTGAAATTAAAAANAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
CH@CGGCIFI@C@I@BAD?!CGHA@HDEIE"DDHAAIIHH@CAAEC@B@FA@DBIE?EGEEBHIGHGGDHBF?DAFC@DBB@FDE@EEFCFDIABHEI@A
@>chr21:9675446-9675511-0
TCAGACGGTAATCAGCTGTAAGCTTCCCTTTAGCATGGGTTTGAGATCTTTCTTCTTTTTAATTTGAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAA
+
DHHE@ACFEB@BDB@DGEED@DEEB?DCCABFGFIBDCG@ADEGCB@?DD?FGC?A?BHDDEFCF*?DB?EE?D?@AA@EDFICCHBHC?DF@CAAA@AI
@>chr21:9675446-9675511-1
TCAGTCGGTAATGAGCTGTAAGCTTCCCTTTAGCATGGGTTTGAGATCTTTCTTCTTTTTAATTTAAGCCTCTGCAGAGATCCGAAGAGCGAAAAAAAAA
+
I@HG&CHGB@AA=B@@GHHG?@EHHDBHIHFHFICBG?GH?GEGHFD@DC@(HGIAF@CH@B?HHCCDE:HDIEH@CBDDDG-EGG@@FII@GB?FGACD
@>chr21:9675446-9675511-2
TCAGACGGTAATCAGCTGTAAGCTTCCCTTTAGCATGGGTTTGAGATCTTTCTTCTTTTTAATTGAAGCATCTGCAGAGATCGGAAGAGCGAAAAAAAAA
+
C@@F@HC@???AEFGFFC?BABIDBG@IDACHHIFBACFCDH0FFFIH@FC?G@@CEH?HAC@D,?HCBCDGCIH?CA@F?CHFE@CHH@FBHCCE?GAD
@>chr21:9675446-9675511-3
TCAGACGGTAATCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAG
+
@@?ACGCHBHDBECGA@DF?CFIGIACHH@@?BHAHIGG@BBBHIIBHDEFFIDFDBCIAI@DEBDF@E@HHB@@EHHFAAC?A@ACDDFFDG?@DFH@;
@>chr21:9675446-9675511-4
TCAGACGGTAATCTGCAGATGCTTAAATTAAAAAGAAGAAAGATCTCAAACCCATGCTAAAGGGAAGCTTACAGCTGTGATCGGAAGAGCGAANAAAAAA
+
CIGHGCIFEGBAACE@DDDHIHDABE@HDHICBIF@GEDHI@EFEB?ACHE?DBBBBEHD@EEABAIBHFA@FF@IC2BAFC@GEB?D?BCEE.AIBGEA
@>chr21:9675446-9675511-5
TCAGACGGTAATCTGCAGATGCTTAAATTAAAAAGAAGAAAGATNTCAAACCCATGCTAAAGGGAAGCTTACAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
BCHBIDHGDHE?ACGHDBCAIFEAF?BCEAIC@FECBDAA?GDI6@HIFIFG?ICHGEHEEDCAA?ACGFADEE?DBEEC?DIGBIGDCDADDGFDDECH
@>chr21:9677863-9677927-0
ACCACTATATCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTCAGGCTGGAGTATTTGCAGAGNTCAGAAGAGCGAAAAAAAAAAAA
+
ICG?I@?B0EDB?IAFCHAG?EFFDCDDBHFEBHCFCA??GC@@DIIAE@EFFC@?@E@E@IDAEE@GHBAHHBDG:EH+B@IGIEECH@@IACCC?HD?
@>chr21:9677863-9677927-1
ACCACTATGTCTGCAATCTTTNTTTGTGTGTTTGACAGGGTTTTACTCTGTGGCTCAGGCTGGAGTAATTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
BDCHCGHBIHIBH@BBICIGF:B?E?ICIIF9?@BD?FBGB?CI?FA@EDHGCC@BIHEADFIHBBIDDHEDECI?CC@IIAIACHFAFCEH@@I@@A@I
@>chr21:9677863-9677927-2
ACCACTATGTCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTCAGTCTGGAGTAATTGCAGAGATCGGCAGAGCGAAAAAAAAAAAA
+
GAFBI?H@DDHG@D@5FHDIIIHFE@EECGDHCGEG@EGDD?B?BCF?ABEC@DHBB@*?IA@IBGFAAH@CHDIIGGAE@3HH@??FGE@CGHAHCCHB
@>chr21:9677863-9677927-3
ACCACTATGTCTGCAATTACTCCAGCCTGAGCCACAGAGTAAAACCCTGCCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
@AIH@DHF@C@BBIH@AHDBGFHIDIF@DI?EHGB@II@G?BGGHDCC@,DBFECHDBBHDD@@E?H?IHCBAAIHAEHIHGC?IDCBGBCBIE?IBA?C
@>chr21:9677863-9677927-4
ACCACTATGTCTGCAAATACTCCAGCCTGAGCCACGGAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAANAA
+
DDIFHIEDFFEHA?GFA@@IA?G?GA?DFHC?IBC$IEAGCHBC?CC?EICF?F@G@IBII@CHCAFDDICADDFBHAFHCCH?DCG?F?IAAHBCE3CA
@>chr21:9677863-9677927-5
ATCACTANGTCTGCAAATACTCCAGCCTGAGCCACAGAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGGGCGAAAAAAAAAAAA
+
C=GD?EI<CAI@EHH?HB?CIGDFDDEAGEA?F@HBCEGIHBH?DDFAGGHAGBA?C?H@@GCHGA?GCDFFBHA??G@@IHGB8?CBF?GHBBFFFAAA
@>chr21:9677863-9677927-0
CTCATACCACGCTGCAATCTTTTTTTGTGTNTGTGACAGGGTTTTACTCTGTGGCTCAGGCTGGAGTANTTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
GEDGAIHGBFHA@HIEDHGHBGCFBCGBCD'?FE@?@EAIFBDBEF@EDIECADHCFDEA@I?C@CBH/BGCH?F?EEGHGFBFCCB@FBFGHB?HHCCE
@>chr21:9677863-9677927-1
CTCATACCACGCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTCAGGCTGGAGTAATTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
EBB@AFECFDEDGGCHCGDH.AFG?E?FIFIADDEABEACAGDG@IACA?HEGEFH?@@FIAFGAG?G??ED@IC@HAEF@DDBDDFE@FI@G?CHGHGC
@>chr21:9677863-9677927-2
CTCATACCACGCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTNAGGCTGGAGTAATTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
DD@HIH??BG?BHHH@?CHI?F@HG@EA?GBGGAHBIGBICDFC@AIADFH??GFH)ADAAHFAB@EHAID@B@B?GFG@CIDEFG?HBAGFCHHHG?ED
@>chr21:9677863-9677927-3
CTCATACCACGCTGCAATTACTCCAGCCTGAGCCACAGAGTAAAACGCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
AHE@GCCD@EHIA?ECCBGBDEGC@?DID?A@FHDAEGDGFC?DED%FI?A?CDCEHEFI@?FEHH?IFDF@GBBDCD@AFGCEEBGDGH@A@?C?E@@F
@>chr21:9677863-9677927-4
CTCATACCACGCTGCAATTACTCCAGCCTGAGCCACAGAGTAAAACCCTGTGACACACACAAAAAAGGATTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
IAACADBEDDCCEA@BB?D?HDEDGDHE?EDHIADAICIFDIHFIEEG?AC%BFBEE@CGI?AHBI!DC?DBIIGBEEGHBGGC@?F@BHBFIHIIF@EA
@>chr21:9677863-9677927-5
CTCATACCACGCTGCAATTACTCCAGCCTGAGCCACAGAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGATCCGAAGAGCGAAAAAAAAAAA
+
G@HAEB?ECAIBGGI@CFHDH6GAFEE@IEEAAHHDBA?EAB?@EEDG???HIECB@HAICFDCFEFECC?CIAA?HEED6CIBIG@?H@CGCC@IHCH@
@>chr21:9677863-9677927-0
GAAGGTCCTCTGCAATCTTTTTTTGTGTGTGTGACAGGCTTTTACTCTGTGGCTCAGGCTGGAGTATTTGCAGAGATCGGAAGAGGGAAAAAAAAAAAAA
+
CIF@BGCFAIDG?BA?H@BAH?@AEIHF@DAI/?HD?A%FIHI?EAGH@IECI??DEAH@D???ECHBAF?CGCIFCFAIFGGHA9FDFAAFBIG?HAEE
@>chr21:9677863-9677927-1
GAAGGTCCTCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTCAGACTGGAGTAATTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
GECHICBHIDBIDI?DIFH?@FCHIFEAGACBBFIGCHE/@AEDDEBGEDBGH?@GH%IA?CFC@DHCDF?AEC?FEBHFE?ADGEA@CF?AAFA?BGCI
@>chr21:9677863-9677927-2
CAAGGTCCTCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTCTGGCTGGAGTAATTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
&DHA@AFIHGEDE@FB?GD@FCDGBEFAD@B?D?GAIFFGAHG?CH/?@GEFEDI+?DDFC??HG?AHA@IFFHHAAH@IAHFCDI?CHFEDGIGEI?HH
@>chr21:9677863-9677927-3
GAAGGTCCTCTGCAATTACTCCAGCCTGAGCCACAGAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGAACGGAAGAGCGAAAAAAAAAAAAA
+
G@H@@CIC@CG@GCHBC?F??HDDGII?HG?ACDEFA?GGB@CFBH@E@??HHDGIDG@@?AFCHDG@AFBHC?HF>G?IFFID@BA?ACGBIFA?A?GH
@>chr21:9677863-9677927-4
GAAGGTCCTCTGCAAATACTCCAGCCTGAGCCACAGAGTAAAACCCTGTCACACACAGAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAATAA
+
?GBCCAE?FABFCIBEE?AID?I?AECHCBBD@HDFE?EFD???FFIBHFE@C@HGD<FFCDDF@IB@BI?AFBE?BDCFFG@FICIHIAAHC@?GH3A@
@>chr21:9677863-9677927-5
GAAGGTCCTCTGCCAATACTCCAGTCTGAGCCACAGAGTAAAACCNTGTCACACACACAAAAAAAGATNGCAGAGATCGGAAGAGCGAAAAAAAATAAAA
+
HCHIIDBCHGHBG6HE?D@DGE@C1FC?FI?ABEGFBIA@CBEFB5FHECHAC?AFDAAFFHD@C?EI!CDAIDFGGECEDHBIHG@?IHEF@DH<I@GG
@>chr21:9677863-9677927-0
GCGGCGTACTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTTTGTGGCTCAGGCTNGAGTATTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
FIDDBEA?@?HGBHB?GDECDCIBGC;FHAAH?C@FBFDDBCHFA"IADHCAGIAIC??*F@?HFBEE@DGAC@FBEG@E@IBGAGHBCGHDIEAEHFF?
@>chr21:9677863-9677927-1
GCGGCGTAGTGCAATCTTTTTTTGTGTGTGTGACAGGGGTATACTCTGTGGCTCAGGCTGGAGTATTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
EGBECG@D1DIAHBFBHGAA@DDAEIEFGEI@G??@AC9E=FDBDFHI@C@G@HC?F@ABABCDEIF?GIGCCD@HECCHGIFDA?IIBFIIBBBFIDBC
@>chr21:9677863-9677927-2
GCGGCGTACTGCAATCTTTTTTTGGGTGTGTGACAGGGTTTTACTCTGTGGCTCAGGCTGGAGTATTTGCAGAGATCGGAAGAGCGAACAAAAAAAAAAA
+
FCFG?HCHDDEEECCH?GI?CB?C<IH@ACGBEDGEBAFF@@@CGG@FAIB@C@?GHDEBDI?GFGF,DCDC?DAIFEC??E5C?IDG%?HDHAG?ICBB
@>chr21:9677863-9677927-3
TCGGCGTACTGCAAATACTCCAGCCTGAGCCACAGAGTAAAACCCTGTCACACACACAAGAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
#@EFFAEEG@?GCDCF@CD?AH@CGEB@CFB(C?FGCF?HCEAD@?IDEFICABFIFCG)D@E@DCAHAFGAG?ID@HABCACFGGCAI?5HIB?ACFA@
@>chr21:9677863-9677927-4
GCGGCGGACTGCAAATACTCCAGCCTGAGCCACACAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
AC@HCD8@HGCA?BIA@?GABF?CA@?FHBADEI2??GFBAHDBBDFI?FDECGFIDGHFGHHB@GC@AEBAF?DHGFBCEDDBDI?@HA??BHIEB@DH
@>chr21:9677863-9677927-5
GCGGCGTACTGCAAATACTCCAGCCCGAGCCACAGAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
GB?AFAFCGHI@@CF?B???GAFAI"?F8DFGDCHF?@BB@DGIB?HCEB@CCA?DIEEBCAGAIE@IFEHHGI@HBBH@BC?DE@FBIHDIEDHH@@?E
@>chr21:9677863-9677927-0
TCAGACGGTAATCTGCAATCTTTTTATGTGTGTGTGACANGGTTTTACTCTGTGGCTCAGGCTGGAGTAATTGCAGANATCGGAAGAGCGAAAAAAAAAA
+
GD@F?GAEIDECC@BEDEGDEEGA?8IBBFEBFD@GFH?&@??@DCBDAI@?BDGEABED?EDDDE?E@DE@ECEHC;E?DEEFC@E?BAHEIICICBG@
@>chr21:9677863-9677927-1
TCAGNCGGTAATCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTCAGGCTGGAGTAATTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
CHAH=IBGF?FE??AIEEHHI@DI2A?CAGBCHFEHC?ADBDFBBIH?DGCEHECHCDIHFDAHHBBBIEBEGCDEICGIEDAF?IDEFHFHEAEFA??A
@>chr21:9677863-9677927-2
TCAGACGGTAATCTGCAATCTTTTTTTGTGTGTGTGACAGGGTTTTACTCTGTGGCTCAGGCTGGAGTAATTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
D@DIG?EF?HAF?ECHHEEF?EI?E?B?I@B@EB@@AC?HI?B@HAFCFCH=HBDAF?G@HEHIIB?HCAD@D??HHBHIHC@ICIC@AGIHGACFFGBF
@>chr21:9677863-9677927-3
TCAGACGGTAATCTGCAATTACTCCAGCCTGAGCCACAGAGTAAAACGCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
BDFBDE?FCAHFGHC@HFF@CIGEIEBHCEGFEFDGH?F?B@@BABH#GFDHBICCD@CD?IGHA@FEDFFFHCEIIDIAF?@?DD@BD@A?IFIHE??E
@>chr21:9677863-9677927-4
TCAGACGGTAATCTGCAATTACGCCNGCCTGAGCCACAGAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
?DFD?I@?BIGBFFCFH@FDGE(GD$B4I@??CHC?BD??E@AAGHBGF??ACBFGCHCBCCEBII?H@@CCEBEFE?CEH?IAB@HIB?HFC@HEII?G
@>chr21:9677863-9677927-5
TCAGACGGTAATCTGCAATTACTCCAGCCTGAGCCACAGAGTAAAACCCTGTCACACACACAAAAAAAGATTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
HFH?2@GEIBEFB@IAGCGC@D?EBEGBGEEBFCAAHHBCGDBDGFA@HAAE?ED@HCHC@ICBBHA?FEBHDDCHHFFIGFH@HAADH?HF?AAF?BEF
@>chr21:9679732-9679825-0
ACCACTATGTCTGCTTTATCTTGCGCTTTTATGTTATGAAGAAGACTTTTTTCCTAAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCTG
+
!AE@IGGIGICA@AAHFCA@D@IGAAFEA!G?EIIDDBCIFIF?AICEFAGCGIAIGAEAIGH?C?BDIGGFFCEDAIEHFCHHFE@BH&@DFGBGBI?I
@>chr21:9679732-9679825-1
ACCACTATGTCTGCTGTATCTTGCGCTTTTATGTTATGCAGAAGNCTTTTTTCCTAGAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCTG
+
AD?@IBBBDFI@AEF$BIEHA?HBDGFAFE@IE@?GAA3CCGEH'DEACHDG?@FF5@@DDGCECF@GBBAAG@AA?GDF?EEB@GEGEAH?CGIH?CGH
@>chr21:9679732-9679825-2
ACCACTATGTCTGCTTTATCTTGCGCTTTTATGTTATGAAGAAGACTTTTTTCCTAAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTATTCTTCTG
+
?HAIBGAIEFHCDD@E?GD@HFHE?IBCIH@F?G?G@F?G?F?BEBBCHCIBBIG@IGFAC@C@IAC?HCGAFC@IFFAIH?EFHGBCDDD"?BDHFAD?
@>chr21:9679732-9679825-3
ACCACTATGTCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAGTCTTCTTCATAACATAAAGGCGCAAGTTAAAG
+
EEBA?F@CECFGHFBAE@I??G?@BIEHBAEFB@DA@FECADG@H?C?FHGGDB@B?@I@DE?@?BHIEE@DHIA@AC@EFGEGC@!EI@F@@B"BIDCD
@>chr21:9679732-9679825-4
ACCACTATGTCTGCAGAAGAAGAGACTGAAGCNAGAAGAGCTTGTTTCTTGAAGTTTTCGGAAAAAAGTNTTCTTCATAACATAAAAGCGCAAGATAAAG
+
ICADHFA@CE@@EBBAEG@ED0@F%EBDAH@B#ADB?@FH?IHCAGECDACGBHCCHB9GAHIADHCBH+HFEBIDFCGI?CE?AICIHDCD@AGIEC@A
@>chr21:9679732-9679825-5
ACCACTATGTCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAGTCNTCTTCATAACATAAAAGCGCAAGATAAAG
+
AEB@IAGHCCGBCD?CG@?HE@?EEFHAHF@CGAB@CEDHHF@BIBHAGF@IEDIADBGAGD?FII?A@G$CEDEBHB?C?IE????DH?D@?DCHH@HI
@>chr21:9679732-9679825-0
CTCATACAACGCTGCTTTATCTTGCGCTTTTATGTTAGGAAGAAGACTTTTTTCCTTAAACTTCAAGAAACAGGCTCTTCTAGCTTCAGACTCTTCTTCT
+
@@ICGDF3I?AH@DEEBAFDFFD@I@GDE?@??H@@B7ACEA@FDGBFHGFIDCGACEAIHHBBCEHFGEGA+AH??B?FBBFBBGHFFGGBCDHCFEDF
@>chr21:9679732-9679825-1
CTNACNCCACGCTGCTTTATCTTGCGCTTTTATGTTATGAAGAAGACTTTTTTCCTTAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCT
+
AC'?'6BDDCDCCGCIADBI@IDHG?GFCC?I?AGH?BC@HII?FBGG'EGGBGEDAD?HIBCCFCGAIGHI@IC.@?ABCADICGGFFAI@CDE@I@CE
@>chr21:9679732-9679825-2
CTCATACCACGCTGCTTTATCTTGCGCCTTTATGTTATGAAGAAGACTTTTTTCCTTAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCT
+
AAEAB?H?EDFGEFBBDAACAEEDGCA!DFACBEIFI?DAHCIFCEIAHBI@HIIBHA@E@@CCI?HFCCACDFFHAIH?HEGAAFBCDBB?B@IF?CGB
@>chr21:9679732-9679825-3
CTCATACCACGCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTAAGGAAAAAAGTCTTCTTCATAACATAAAAGNGCAAGATAAA
+
CICEIBEB?D?H@H?H@A@@DBBBDEFAHFAD@DC@@E?HGHGBHGBIC@D@?@EGDAFEGGGCHCF@HFFEBCDDDHCI?AC?FE?EE;FBIDHABDHC
@>chr21:9679732-9679825-4
CTCATACCACGCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTNTAAGGAAAAAAGTCTTCTTCATAACATAAAAGCGCAAGATNAA
+
ADCI?FEIFGACAEIAGAFHED4HEIBI?EFBIHGABDC?I?CIFCEG(CEDEF?I4BIGDCBEE@FFDIB?FCACAGD@@CADDICFG@@BA@?HF*IC
@>chr21:9679732-9679825-5
NTCATACCACGCTGCAGAANAAGAGTCTGAAGCTAGAAGAGCGTGTTTCTTGAAGTTTAAGGAAAAAAGTCTTCTTCATAACATAAAAGCGCGAGATAAA
+
:@@EHDDC@BBGIDIHBGC!ECDCDAC@AFBAAD?HDFA?A@3?IDEBCHHHIGHIHFDGBF@HEFBAHEC?G?EGGAA?FD?H@HHDCFFD&IG??GA?
@>chr21:9679732-9679825-0
GAAGGTCCTCTGCTTTATCTTGCGCTTTTATGTTATGAATAAGACTTTTTTCCTAAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCTGC
+
C@H@AABAGAH@?DIBCIEDABFFIEE@@HCEADA<CC?!GFCIACI@IEG@DBFI@B?ICEED?@CAGDIGBGBEAGDGBAGB?IFGHDCBAFAFFCHD
@>chr21:9679732-9679825-1
GAAGGTCCTCTGCTTTATCTTGCGCTTTTATGTTATGAAGAAGACTTTTTTCCTTAAACTTCAAGAAACAAACTCNTCGAGCTTCAGACTCTTCTTCTGC
+
CBEBFE@?D?B@CIDI?FEI?IIHCCF?GIBH??DGIBAG?AHBBGAGGBEGHCEEBDHAFIFEGEHIAEE4EG?<BH"HAHGFBID2FC@IDBAA?AFC
@>chr21:9679732-9679825-2
GAAGGTCCTCTGCTTAATCTTGCGCTTTTATGTTATGAAGAAGACTTTTTTCCTTAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCTGC
+
HDBG?G?HBFGG?DB<CB?EC?CI?CECEGDFE@@EIFEEAFG@HHFABCCDGGDCIB?@BA@BBIGH?C@EEG?BD@EI?DBAFIBBHFIAEB?B?@@A
@>chr21:9679732-9679825-3
GAAGGTCCTCTGCAGAAGAAGAGNCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTAAGGAAAAAAGTCTTCTTCATAACATAAAAGCGCAAGATAAAGC
+
@I@FAHFGFF?GCE@IABIDD?A3H?H@FFEG?AAGDIDH?CFCHAFG@EEFBBDF@E?ECDAAICFCHIEIIDFBGB?ADFHDC?FAADE?@?BIABEB
@>chr21:9679732-9679825-4
GAACGTCCTCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAGTCTTCTTAATAACATAAAAGCGCAAGATCAAGC
+
?A@)BDGDFFGII@IFCA%HBCFH@CCHEEF?CBFHHFBII@IA@BIAFDHDA?CAEIGAEDA?AG@BBIIDIH$CCEA?BBGBIFBEIGC@EIH/?III
@>chr21:9679732-9679825-5
GAAGGTCCTCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAGTCTTCTTCANAACATAAAAGCGCAAGATAAAGC
+
EG@BHC@DIBH?FIICFADGHECDDFIAGBBBF?AAA@BG@DIB@?DHCB@CBBFCGE?I@ED@?BF<BFG@BIAC8A?CHGDDA@E@GCEEIEIGCG)C
@>chr21:9679732-9679825-0
GCGGCGTACTGCTTTATCTTGCGCTTTTATGTTATGAAGAAGACTTTTTTCNTAAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCTGCA
+
IGEECDHGADBEDGG@BEGCEBADAHIE@ICECFBEA?CGBBC@BH@DGB@4ABHIF?IFCCDAD&GIHDGHBG@BC@FGEAIAGCEFBFIIEHIIFIGD
@>chr21:9679732-9679825-1
GCGGCGTACTGCTTTATCCTGCGCTTTTATGTTATGAAGAAGNCTTTTTTCCTAAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTCTGCA
+
FACABB?G@@CAH@H?BA5DCCBABBDBGDI?F@AGI@IFGB'@ECEIDFAEH?IHGAGADGIF??F@FA@EBHIHHCHDBHGBB@GCEFAACEGIFDHE
@>chr21:9679732-9679825-2
GCGGCGTACTGCTNTATCTTGCGCTTTNATGTTATGAAGAAGACTTTTTCCCTAAAACTTCAAGAAACCAGCTCTTCTTGCTTCAGACTCTTCTTCTGCA
+
@DHI??AH@A@DF=GIHBF?DDGCB@B'GDEGCDIGH?GEE@@B?IIIG5EA?DHHDEBGC??HHGEB1AGDDEBHBE2GFBABDE?IEDH@AEG?FHBG
@>chr21:9679732-9679825-3
GCGGCGTACTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAATCTTCNTCATAACATAAAAGCGCAAGATAAAGCA
+
ACGAEIBCBAF@B@GAGGF@BAHEGEDBGBHI@DC@EAB?I?BDDFIHH??AC@GECF@CIFI@G<ADH@@$AFFCIC@?IGD@ECCCBCGFGDAFGCBG
@>chr21:9679732-9679825-4
GCGGCGTACTGCAGAAGAGGAGTCTGAAGCTAGAGGAGCTTGTTTCTTGAAGTTTTAGGAAANAAGTCTTCTTCATAACATAAAAGCGCAAGAGAAAGCA
+
?H@GBCFFDCDECA@I?@<ABBDECEG?FIAG@C%ID?IHI@D@BBGAFCEC?CGBEHH?BE%DAEAGDHI??E?@HGIHEBAECHG@IGEGF(GEF@AB
@>chr21:9679732-9679825-5
GCGGCGTACTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAGTCTTCTTCATAACACAAAAGCGCAAGATAAAGCA
+
FB?H0DDCE@CGDAIEIDEBCFAC?@H@?B?GAIA??HEHDE@@?EFFFEH?GAAICEI?D?E?AAIBD?@IFB?CDDEG:C?FGF??CCF?B?@FE@CE
@>chr21:9679732-9679825-0
TCAGACGGTAATCTGCTTTATCTTGCGCTTTTATGTTATCAGGAANACTTTTTTCCTAAAACTTCAAGAAGCAAGCTCTTCTAGCTTCAGACTCTTCTTC
+
EGIGADIABB?B?I@IA?B??ED?GGH@DBIEGIEDDH?:I>?E?8B@BHECICDCEE@ABEBAGCGCE@4C@GB?@@AI?D@@@HCDIIE@E?HDGADC
@>chr21:9679732-9679825-1
TCAGACGGTAATCTGCTTTATCTTGCGCTTTTATGTTATGAAGAAGACTTTTTTCCTAAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTC
+
FFHIAFFDCECGD?BGA?EGBFHA@@HFC?BHB?C?HFBFIIEAF@C?GGCIFHAC@AE@DFG@DIGAGDFACEICGEDFEDDFEBCAAAD@?CI??FGC
@>chr21:9679732-9679825-2
TCAGACGGTAATCTGCTTNATCTTGCGCTTTTATGTTATGAAGAAGAATTTTTTCCTAAAACTTCAAGAAACAAGCTCTTCTAGCTTCAGACTCTTCTTC
+
FAIFII?ECCCI?GHFB?%?IBHC@D?EGCAAGACGBFGGAHB?@G@,A?DABHBHF&CA@CA@GFDEGHBIBFIAFAACHAG4ACHF@CDDE?AFDBAE
@>chr21:9679732-9679825-3
TCAGACGGTAATCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAGTCTTCTTCATAACATAAAAGCGCAAGATAA
+
H?A?DGCBAGF?FFEEIFCIFC??E@HC?EFGF6?DE?ICIIDDGEGDGGGI??G??AEFFBAH@EGFFHDBDHEBAHFFDAHG?ABGABD@A@IBE?IE
@>chr21:9679732-9679825-4
TCAGACGGTAATCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTNTTAGGAAAAAAGTCTTNTTCATAACATAAAAGCGCAAGATAA
+
I?EDF?EDDBDCEEBH???FCB@BAA@AEGBIGAI@CEF@DBABCDGCFFF@D@HDH;HH?IGDEDCB@DH?DI)?HBGICBF?@?G?C@EEAIBBA@CC
@>chr21:9679732-9679825-5
TCAGACGGTAATCTGCAGAAGAAGAGTCTGAAGCTAGAAGAGCTTGTTTCTTGAAGTTTTAGGAAAAAAGTCTTCTTCATAACATAAAAGCGCAAGATAA
+
GABAIA.@HHIHGF?A?CAF?E@?E??HHDA@CADFHCGAGCABHFCEEC?F?D?HICECHBCI@C@DHCA?IGHCBBIH@AAAEH@@DDIF@ICAGFGA
@>chr21:9683243-9683338-0
ACCACTATGTCAGCAGTGTTCTGGAATTCTATGTCAGGGACATTCAAATCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCCC
+
BFHDBAH?@C@BGBABEIIGD?BEE@EBIFGF@I.@II?DGGCFIBABAA@?HBAIEA@?H?H?DCEBI?DECHH@DCB?DIDEBAGH@EF?DDFEEG@E
@>chr21:9683243-9683338-1
ACCACTATGTCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGNACAGGCGTTCAGACCCC
+
EDIADGCBH?EBICGCCBECGG@BEH@DGGGEF?BCAI@C??CC@E?;C??F@BGDAE@IEH?I?FHIFBI@FHHGFDG@??>FCIC1FD@GCIDF?AI@
@>chr21:9683243-9683338-2
ACCACTATGTCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGTCGTTCAGACCCC
+
GBAIIHF?CAIAE?B?F@FA?AAHE@EEDH@AD?FC@FI?C?DGC@IECG?AGCHDA@GIG??CFADEHGE?DHFCIHIGFCHECDC3HFCF@?HBGI?@
@>chr21:9683243-9683338-3
ACCACTATGTCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGGTTTGAATGTCCCTCACATAGAATTCCAGAACAC
+
AGHBHADCGIIGAII?DF??FCCFFEI@GDFBAGF@EHAEFGEABHAEA?EG@?ABBB?EGCA?C?HBCIA@4FH?HIFBD@B@B@?H=EEIF@HE@GFF
@>chr21:9683243-9683338-4
ACCACTATGTCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGATTTGAATGTCCCTCACATAGAATTGCAGAACAC
+
BIGGID?IBGFAA?@?CFD@BICH@BEHGC?DHAFFA?GABHHB?@CDE?GBGC@IAD@DBBHIGEHEHFGGHAI@E?CAFBE??EAEHCE,IB@?E@DI
@>chr21:9683243-9683338-5
ACCACTATGTCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGATNTGAATGTCCCTCACATAGAATTCCAGAACAC
+
HDAA@GDBIFFAGDH?HBFBAFH??ABEEG?CHGAGBEI??HHAFFFDIHEI@C@?IIGHF@@G?EDB%IIHDFBFBG?FH?IDAGBDFCICBHG@CHDC
@>chr21:9683243-9683338-0
CTCATACCACGCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAATCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCC
+
FG?HECEAIH?DFFFCABI?EFGFGHF?FC?@AIBAHAEDCFFCF?EIFDDHBFBH?@AIAAEHCCFDADDD@@CDDD?EBIG@AE@DG?I??HGFDDHD
@>chr21:9683243-9683338-1
CTCATACCACGCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCC
+
HHGB??GIAF?F?FD@HEGGGBFCIEECEAA?AG@ABAIBG?DADAA@IBFC?CAIA@ECH@AHE?@@?A@FE?A@@CDFIB?DE?CEIEA:AAGIIHBB
@>chr21:9683243-9683338-2
CTCATACCCCGCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAGTGTTCCAGAATCCTATGTGAGGGACAGACGTTCAGACCC
+
@BFD@BC?2G@DC?CBIEFHI@FF@HEHDBFFEBA??CGAD@@I@FCIEDHIIFBAIFIEDFFEBI,HAFHAAI@GDGDGC@HBCDCE??AFFGBICDC@
@>chr21:9683243-9683338-3
CTCATACCACGCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGGTTTGAATGTCCCTCACATAGAATTCCAGAACA
+
CCEHIEE@IBAFDACID?DECH?EA@HHDBE@DBBB@AIAAA?ICECHFBI@GIGB@AICFE?CCH@GFEIAGIECFE?GA?IDD?BIBFGGI@IG@I@B
@>chr21:9683243-9683338-4
CTCATACCACGCTGCTGGGGTCTGATCGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGATTTGAATGTCCCTCACATAGAATTCCAGAACA
+
@B?ADIG??BAHC?HGHA?FE@??C'HE@CICDC?DBGGB@BGFAIE6ECIGF@?D?FGDFBCAGEEID@CEGEE@FEHE@HFHAIIHDIH@BCEEE@@I
@>chr21:9683243-9683338-5
CTCATACCACGCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGATTTGAATGTCCCTCACATAGAATTCCAGAACA
+
HIBBBB??AC??AGFFDAIFIBHFEFADAFD@ECH?GADDEGCE@FHHAIEHEGH??F?CGAAFHDDDFBGEF@HBEBAHGCHDFEGIBI;I?HAI?DCC
@>chr21:9683243-9683338-0
GAAGGTCCTCAGCAGTGTNCTGGAATTCTATGTGAGGGACATTCAAATCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCCCA
+
@CADG?BF?IBBDA@E?I!HD?EHCDEIDDDBAGGAGF@CEGADBFHDDDIGGBDG?BDCDBCEEFD0@AI@I@FFEEAAFDFFG?A?DGFDCIII@G?I
@>chr21:9683243-9683338-1
GAAGGTCCTCAGCAGTGTTCTGGAATTCTNTGTGAGGGACATTCAAATCCCAACAGCAGTGTTCGAGAATCCTATGTGAAGGACAGACGTTCAGACCCCA
+
DA?@IBF@?BD?GA.DFGG?E??AIBBEI/CA@BCE@EGDG?DCEIFGBICIEIFECFDABBC?/ECD@GIE?GFFCHC0BDB??GHDB?DFAF@?GACG
@>chr21:9683243-9683338-2
GAAGGTCCTCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAATCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCCCA
+
I@FEICCGF@FBIIIDIDFBHHEFH@?IFHDFCBCG?EI?IB?F?IA?GB?GH@@AID@DIGGBGBEBBH@FBB@@@BAGBC?DDHGGH@FAHEIDGCAD
@>chr21:9683243-9683338-3
GAAGGTCCTCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGATTTGAATGTCCCTCACATATAATTCCAGAACACT
+
E@GFI@@HFI@CBIIB@DGAIIHIFGGCG@AHB@E@E?AGA@HGDG@ABAIG@FBHHCIBIE@CA@DHHE?EGIFHE?@EFBCAE<D?BB?DFICC?A?F
@>chr21:9683243-9683338-4
GAAGGTCCTCTGCTGGGGTCTGAACGTCTGTCCCTCANATAGGATTCTAGAACACTGCTGTTGGGATTTNAATGTCCCTCACATAGAATTCCAGAACACT
+
EDBF@GHHGEHGI?FF?CBC@DCDBFEGD?G?DIBDC'?FEHHBBGGFA?GCDADADIIDAE?ABFEFH4DABFBFEDGAFBCDF?@?@HDFD@ADIGFB
@>chr21:9683243-9683338-5
GAAGGTCCTCTGCTGTGCTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGATTTGAATGTCCCTCACATAGAATTCCAGAACACT
+
EAIBGAIBEGBGCEG8E=?AEADBIEIEF@?F@AFHAEIH@HFCF?AHDCGGGBFAB?D?GHGCHICBBGAGE?@D?IBCGFGHE?CCFB?IADGEBGBE
@>chr21:9683243-9683338-0
GCGGCGTACAGCAGTGTTTTGGAATTCTATGTGAGGGACATTCAAATCCCAACAGCGGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCCCAG
+
GIGBDGHHHHIEAFEHIE6CFGEC@GA?GCH@GDDGIICC?GCFFCFGD?F?HEFE+IABDHB?IAEGBBBHFF?@G@?E@DHCA?CBEE@?BEAH@HCG
@>chr21:9683243-9683338-1
GCGGCTTACAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCCCAG
+
C@@AA-ACGBFHD6EEGD?A?CBD@BEHG?EI?AECB@IFF?CFCFHECIA@HFDGHFEHCGFGBFDEIIIDFBF???B?BHAGH?GA@FAFCCBI@AGD
@>chr21:9683243-9683338-2
GCGGCGTACAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAATGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACCCCAG
+
HDI?@?CF?EGAHBIEHEEHFCGEFAG?CG@FBAAICGGICI?CBHCHHBEEEECD?.AC?EB@?IGD@D?BIEFH?ADCCA?H@BDBH@@CE?EAFFBA
@>chr21:9683243-9683338-3
GCGGCGTACTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGGTTTGAATGTCCCTCACATAGAATTCCAGAACACTG
+
IF?F???GDGIBDDDB?EI?G@HGHA?EDC?DECGFBDGAGD@DEBGGC?EGACB?BH?ABDCGGFB@IEF@CFCDHAHEDEAEBEEACID)GHD@H??A
@>chr21:9683243-9683338-4
GCGGGGTACTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGTACACTGCTGTTGGGATTTGAATGTCCCTCACATAGAATTCCAGAACACTG
+
HHEA/AEGAAH?EC?EIADHAICH@DE@?BB@?EBIDI?@AEBBGAIDH=@DEFDHAAFFDGHDIDHBBABCH@C@F@EFIBIICDE@HAG?EAG@G@FA
@>chr21:9683243-9683338-5
GCGGCGTTCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGATTTGAATGTCCCTCACATAGAATTCCAGTACACTG
+
CEF?HFH6HIBHDDDCGE@?FBEHGFCGEFFGGI?F@?GFEFI?GI?I@AD@IEFAHBGDDIHIGE@B@??HEH@I@?BHGB?B?BGGDDBGC5E?@C?@
@>chr21:9683243-9683338-0
TCAGACGGTAATCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACC
+
H?@A?IDDDCHGDGCCHDDADHEE?AAAHAIGIHHGBF?HC@BF?GCCFBA??AHGCEE@FEBGHEDHFBHDCAADFD@?@FF@GBEBD@?EAEBIFGGE
@>chr21:9683243-9683338-1
TCAGACGGCAATCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCCCAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACC
+
?G@BGEDA)BFCGGCDCDIBGIFFBBFHDGECEGI?B%DEDADEEA@AHGICADACD?BE?@@F@FGGBE?DBFAC?AH?AI?HABIE@GH@@FEHCEDE
@>chr21:9683243-9683338-2
TCAGACGGTAATCAGCAGTGTTCTGGAATTCTATGTGAGGGACATTCAAACCACAACAGCAGTGTTCTAGAATCCTATGTGAGGGACAGACGTTCAGACC
+
?F?CGEGBAIHDG??DAFEFAC=CFEHFCIGB?CAIC@I?EEFEE@GGCFCE3GDEAABIDDAEHCI?BE@IFBD?DAG?HBAEICGBAE@A?FFF?DCF
@>chr21:9683243-9683338-3
TCAGACGGTAATCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCGAGAACACTGCTGTTGGGGTTTGAATGTCCCTCACATAGAATTCCAGAAC
+
?EECIBBCAFDGIEEBBDEGEA?B@GACBBDH?CFFEBEGECHI@@DFCB,HDCDEAHB?@CD?BBEBIHEDBIAFICI?GEA?IH?CGCFEGEG?GAHE
@>chr21:9683243-9683338-4
TCAGACGGTAATCTGCTGGGGTCTGAACGTCTGTCCCTCCCATAGGATCCTAGAACACTGCTGTTGGGGTTTGAATGTCCCTCACATAGAATTCCAGAAC
+
ADAG?FBIDB@FGGDC@A?CAIFBB?HHFHBB?AHFDF36G8@GCI@C8FGIDDBAF??@I?B@A@GG?F?HFGFEH?ICEFI???DDCDFA@HDDBFCC
@>chr21:9683243-9683338-5
TCAGACGGTAATCTGCTGGGGTCTGAACGTCTGTCCCTCACATAGGATTCTAGAACACTGCTGTTGGGCTTTGAATGTCCCTCACATAGAATTCCAGAAC
+
DHAB@IIGHGEDGIAEIDFCGAHFCA?GFFEHEEGGHBAEBDG?EGBFHIEBBDB@AAHGAEIDIFDE4?@FGE@CBC@BDAAFIHCFEGB@ABDBA@?F
@>chr21:9684104-9684203-0
ACCACTATGTCAGCAGTGGTCTGGTATCNTATGTGAGGGACAATCATTCACTCCCCAGCAACAGTGTNCTGTAATCGTATGTGCGGGACAAGCATTCAGA
+
?ABI??G?GFCFEEAEIIAAIFA?@EGB8AGIDCD?GGGH@FA"HBFAGEDHGCDC"CAEGFFHFDG"@FABF@IFF@C@CECEHFDBHI@AICAIEGIB
@>chr21:9684104-9684203-1
ACCAGTATGTCAGCAGTGGTCTGGTATCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGAGGGACAAGCAATCAGA
+
EBBI%FDHE@BEEHID@IDBGIBHIFDD?FEGA?DE@DH@HBH@FBEGH?FAII@B@CBIC@IBGBFGGH?HFFGEACIBDBIIE@BCAABEHE4FAA?A
@>chr21:9684104-9684203-2
ACCACTATGTCAGCAGTGGTCTGGGATCCTATGTGAGGGACAANCATTCACTCCCCAGCAACAGTGATCTGTAATCGTATGGGAGGGACAAGCATTCAGA
+
DIAAAHHIBFIBBHGDCI?FACGA=DAH?IEIH??A?HA??H?:FFAACAIACAGCEH?E@EDABB2C?BBBHEIFCE?A@,AEI@EIF?H@EG?HBF??
@>chr21:9684104-9684203-3
ACCACTATGTCTGCTGGGGTCTGAATGCTTGTCCCTCACATACGATTACAGAACACTGTTGCTGGGGAGTGAATGTTTGTCCCTCACATAGGATACCAGA
+
FEAA?IDDGI@EG?GEABIEAFBFBDCHGD?IE@ADIAG?CIEIACGDB@EIIDAFB?CBDAD?HC@@?@FAAI?EHFIFGCHCGGHCGCGBCIFAIC?G
@>chr21:9684104-9684203-4
ACCACTATGTCTGCTGGGGTCTGAATGCTTGTCCCGCACATACGATTACAGAACACTGTTGCTGGGGAGTGAATGTTTGTCCCTCACATAGGATACCAGA
+
CBBCG?BH?F?DCIEGDB?FACAFGAFI@FGAEGHGHIEFCAFIFA?BCF?FGD@F?DC??H@@IAHD?GFIF?@?HGAE??GHC@H?D?EIEHBFCCBI
@>chr21:9684104-9684203-5
ACCACTATGTCTGCTGGGGTCTGAATGCTTGTCCCGCACATACGATTACAGAACACTGTTGCTGGNGAGTGAATGTATGTCCCTCACATAGGATACCAGA
+
HGG?FCFBEDFGIGCEHD@A@AAIE@FI?AIGF@GDEBDHGC@CBBBEIHHBCFCCCBHIBBD?F1GAC?EEIHBH+FC@?GDB@DEBE??B?FHHCIIC
@>chr21:9684104-9684203-0
CTCATACCACGCAGCAGTGGTCTGGTATCCTATGTGAGGGACACACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGCGGGACAAGCATTCAG
+
HAAGHAACHAB?GHD?FBI@BCFDC@DHHECFFIDHABBGBHE3FHHHIFCGBD@EHDAB@H?FDDIBHFAEBH@FDFCICA@C?EGC?AH@IEDGBDG@
@>chr21:9684104-9684203-1
CTCATACCACGCAGCAGTGGTCTGGTATCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGCGGGACAAGCATTCAG
+
ICFGF?E?GCGGGFDIIGEIGEDCEGEAIAIB?C?A?IF@F?GH?H@?I@HDHHGHHAHEED@?DBE@EB@GHBEBEHF?@DG@E@DGDCEIICBDBE?H
@>chr21:9684104-9684203-2
CTCATACCACGCAGCAGTGGGCTGGTCTCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGCGGGACAAGCATTCAG
+
DGABB?G??GCEA?CDBEHE=I@@@F%EAICCIEB@DAIGB@EADIHHICG@EBFFDF?FGEEABH@@C?EFGABGGDEGFAEC@@?IAFGCBIFC@HAI
@>chr21:9684104-9684203-3
CTCATACCACGCTGCTGGGGTCTGAATGCTTGTCCCGCACATACGATTAAAGAACACTGTTGCTGGGGAGTGAATGTTTGTCCCTCACATAGGAAACCAG
+
H?@EADCDBBBBCDHHHHCHIDHD@@DFAFAF@?FIEHDCIB?GFGDIG"@@HGHCH@CB@@CGIAGCEGDFDAAI@GB@D????DGC?HEGHB/IDF@F
@>chr21:9684104-9684203-4
CTCATACCACGCTGCTGGGGTCTGAATGCTTGTCCCGCACATACGATTACAGAACACTGTTGCTGGGGAGTGAATGTGTGTCCCTCACATAGGATACCAG
+
IGDDFEBHAIEFHFHHFBIHEBDIAFHAHIDGDDGEHCHC?E@@CG@HACCDIDCHF@?HA?I?@AEICI?HGD@HB=D@IIAE@ICDCBBBH@GCCDB@
@>chr21:9684104-9684203-5
CTCATACCACGCTGCTGGGGTCTGAATGCTTGTCCCGCACGTACGATTACAGAACACTGTTGCTGGGGAGTGAATGTTTGTCCCTCACATAGGATACCAG
+
DAH?BBBFDCAIDFFG@C@CGE@D@AHEEG@EHIB?IF@D;EDCICAEDIHH@BABI?IG@D?FF@AFHAFE?DEBCDDFGHE?E@GBBABAIFBDIHED
@>chr21:9684104-9684203-0
GAAGGTCCTCAGCAGTGGTCTGGTATCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGCGGGACAAGCATTCAGAC
+
DCDDEHAD?EDCFFE@D@CEACHDADCHEHAD@CII?DG@@ICIBDDGCEBA?FEFBD?AHCFIHDDD?G@HAE?IGCCCDCIGEDFB@HECHHEFA@ID
@>chr21:9684104-9684203-1
GAAGGTCCTCAGCAGTGGTCTGGTATCCTATATGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGAGGGACAAGCATTCAGAC
+
@D@?CD@D@GHGF?E?HGIGDFAFHA?E?AI%EEEDA@BDBCBHGGIHDFAADICDFBIB@HI@FEAGCEGCFDEDECE?DDCAE@AEG@IAAECBGIFC
@>chr21:9684104-9684203-2
GAAGGTCCTGAGCAGTGGTCTGGTATCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGAGGGACAAGCATTCAGAC
+
IDFDGHEII4GFE?D@CBEIAADBI?FIHBF@FF@FDDFDCHF?D?HBAAIFHFDDHE?@AGIACA?AADBHADBB=AHH@@IEEF?FE@BEEEI?IIEH
@>chr21:9684104-9684203-3
GAAGGTCTTCTGCTGGGGTCTGAATGCTTGTCCCTCACATACGATTACAGAACACTGTTGCTGGGGAGTGAATGTTTGTCCCTCACATACGATACCAGAC
+
D@FD?AI3BIBDDDBAFF??CF@FABIHHECCCDDDFID@ECFGHHCAAFC@@DCGAIG?C@@HC@DDHBHDFI@IDHD@GCHD@CDAF#?ABF??FI?F
@>chr21:9684104-9684203-4
GAAGGTCCTCTGATGGGGTCTGAATGCTTGTCCCGCACATACGATTACAGAACACTGTTCCTGGGGAGTGAATGTTTGTCCCTCACATAGGATACCAGAC
+
@CGGC?BFFIHE$@@FBGHGCB?@BI@H??FDAIHHCBCAHDCFICHEGAGFAGGFIIE5?F?HIFBGG?@CHG?CHCCH@G@@FIBAA@FEFAIHF?@B
@>chr21:9684104-9684203-5
GAAGGTCCTCTGGTGGGGTCTGAATGCTTGTCCCGCACTTACGATTACAGAACACTGTTGCTGGGGAGTGAATGTTTGTCCGTCANATAGGATACCAGAC
+
EH?EBEDA?GD?+EECCBADDHE@BFFDHG?EGFDI?C4HFDIHDEDF@@EF@BC?G@BBGFAH?F??C?EIF?HF?EAFF2HCD/GD?@FG?FHB?IGB
@>chr21:9684104-9684203-0
GCGGCGTACAGCAGTGGTCTGGTATCCTATATGAGGGACAAATATTCACTCCCCAGCAACAGTGTTCTGTAATCGTGTGTGAGGGACAAGCATTCAGACC
+
III@CBFHDGCEIFAGICAGHAEBGG?FG?$ECHIBICIHGH3GFG@A?BHDH-F@DB?D?I?IADD@BAIHAA?C0FGCHE@ED@C@FH@CIAB?HBDF
@>chr21:9684104-9684203-1
GCGGCGTACAGCAGTGGTCTGGTATCCTATGTGAGGGACAAACATTCACTCCCCAGCAAAAGTGTTCTGTAATCGTATGTGAGGGACAAGCATTCAGACC
+
FD?EDAA?CDFHGHDBC@CH?GFBA@ACC@G@IIFBFCDHC?@@IGCI@HFBE@FCGFG3GABCBICIHA@I?BAEIH@FAHB?B?CE?AHFHCCCD@GF
@>chr21:9684104-9684203-2
GCGGCGTACAGCAGTGGTCTGGTATCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGAGGGACAAGCATTCAGACC
+
GHCFCEEIFCI@@HCE@FFAEEBAFFFID?BAEEDEDGAG@ED?FH@ADCGD@AC@CA?GGFBGIIFB?E?BHIBEA@?BFBF@@@IIGBABFICABFDA
@>chr21:9684104-9684203-3
GCGGCGTACTGCTGGGGTCTGAATGCTTGTCCCTCACATACGATTACAGAACACTGNTGCTGGGGAGTGAATGNTTGTCCCTCACATAGGATACCAGACT
+
D?FGF@AIBIBEFE?ABBCBEHD?IAADFEGBA@EGCDGIEAGEGFHFD?EH@BED"?HHGHFBCIEDBBBDE>G@C?IH?C@GA?AH?@GEF?GFI@H,
@>chr21:9684104-9684203-4
GCGGCGTCCTGCTGGGGNCTGAATGCTTGTCCCTCACATACGATTACAGAACACTGTTGCCGGGGAGTGAATGTTTGTCCCTCACATAGGATACCAGACC
+
CIGIF@?&FAECG?EDH/BCAEFHHEEGAB?HCHFCDBBHG?BAFBEG?D?AH?GEIG@C'IBAAA?AC@CI?H?GAE@CI@B@B?ABDFG?IEIDE@D?
@>chr21:9684104-9684203-5
GCGGCGTACTGCTGGGGTCTGAATGCTTGTCCCTCACATACGATTACAGAACGCTGTTGCTNGGGAGTGAATGTTTGTCCCTCACATAGGATACCAGACC
+
@DCBAEDHEBB?HA@I?DC@EIDDHCIIIA?H@?@@DADHFACAHAHAF?@A,AEDG@HBH<@CHADEI??C@G?DIB&CCIFEH@FF?GCDE@@DFF?B
@>chr21:9684104-9684203-0
TCAGACGGTAATCAGCAGTGGTCTGGTAGCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGAGGGACAAGCATTCA
+
?DIAEA@C?@?EFDBDGDICDFAD@CCA7GI?DGD?AHHCDBFA?CEBC@GAACBACI?F@??HCA??BA?HFBB?@ICADF??B@BAE@DAECHHGI@G
@>chr21:9684104-9684203-1
TCAGACGGTAATCAGCAGTGGTCTGGTATCCTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATGTGAGGGACAAGCATTCA
+
BDI%@@A@EEECIEACAG?FECADIIFDIFB?EF@@C?BGIIHAEHBEAEF@@FDEEFGH?DBAGAH@HFAHH@GC?FGA@GCCFCGA@@@FGDAAEABG
@>chr21:9684104-9684203-2
TCAGACGGTAATCAGCAGTGGTCTGGTATCTTATGTGAGGGACAAACATTCACTCCCCAGCAACAGTGTTCTGTAATCGTATNTGAGGGGCAAGCATTCA
+
CCHF@AGA?AG@?HAIABIDC@HIHGDAEB5A@IIEDCBEHAHCDE?GECDEFBHCGHDHEI?CA?I?ACA?DG@HBIFGHA#EDABDF:BEFGI@G@DH
@>chr21:9684104-9684203-3
TNAGACGGTAATCTGCTGGGGTCTGAATGCTTGTCCCTCACATACGATTACAGAACACTGTTGNTGGGGAGTGAATGTTTGTCCCTCACATAGGATACCA
+
F/ABFG@CHCHC@??A@I?@BGDCDCDGBBCCHAI?@BGHI?DBD?GFBC@G??@HHD?CCFH4A@@IAG?IDEGGAAI@HFECDEIF@F?D@?@C@@CC
@>chr21:9684104-9684203-4
TCAGACGGNAATCTGCTGGGGTCTGAATGCTTGTCCCTCACATACGAATACNGAAGACTGTTGCTGGGGAGTGAATGTTTGTCCCTCACATAGGATACCA
+
?B@HAF@H9BHCEEEE@FEFCFEGHHGEAA?EECBIIA??CEHD@CI,@DB=BAA5IIHDIBDBB@A@GDEAGCBDC?CCHBGB?AHEEBC?AGB?IBGH
@>chr21:9684104-9684203-5
TCAGACGGTATTCTGCTGGGGTCTGAATGCTTGTCCCTCACATACGATTACAGAACACTGTTGCTGGGGAGTGAATGTTTGTCCCTCACATAGGATACCA
+
HCC@DHA?GD2F?CAAFCBII@?FBFFGGGFHAI@HCD@@IEFC?HGGEAI@GFGBBFA?GGIGHGBB5BD??GCD?@?DGADGIFE@GABAFAAIGHHB
@>chr21:9685108-9685162-0
ACCACTATGTCAGCCGTGTTCAGGAATCCTAAGTGAGGGACCAACAATCAGACCCTCGTAGCCGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
??FEA@EBE@AID?"@GGHBEHBBGIFHAIFEAID0DC@DE?EBFABGHI@EDDG?DBCCIE3DFGG?FI@DBFDCHCEGEFB?FFACDGIACDGFFEG@
@>chr21:9685108-9685162-1
ACCACTATGTCAGCAGTGTGCAGGAATCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
BHDI?FIEFG;@BFIAGC@)DE?DBDCIDFGDGAI@GFI?DGI???CF@GCDG@CCBI@AD@GEEADBCHI?GDH?IC@EBHEIBFEF?IE?B@E?BGCG
@>chr21:9685108-9685162-2
ACCACTATGTCAGCAGTGTTCAGGAATCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
@AHD?AECIE?FF?CA@HCFGDEAGBEBCHHB@AGIDE@EEHHHEFBFIFEGACDECCFBAG@@HHAGDACHHBFHCFBFACIII?A??F?ADA@EF?FI
@>chr21:9685108-9685162-3
ACCACTATGTCTGCTACGAGGGTNTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
FGFHACFCHIHBDCD?=AC?BEC(C@C?IGAGH@GAFFDHFHB?ADDBIE@ACGCEDAEDD@BFHDGGDIDEIEGGED;@?EGGEEEA@@AAIHBCBFAG
@>chr21:9685108-9685162-4
ACCACTATGTCTGCTACGAGGGTCTGATTGTTGGTCCCTGACTTAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
GDEGEAE@@HFBFF@FGBBEBGIAI@ABBBCCC?FDDGG!C?IF?FCCCHHBIHIIHG??EGDIBGGCA?EHHCDDFFCHICBA@?C@G?AGA?FCHB@A
@>chr21:9685108-9685162-5
ACCACTATGTCTGCTACGGGGGTCTGATTGTTGGTCCCTCACTTAGGATTCCTGAACACTGCTGAGATCGGAAGAGCNAAAAAAAAAAAAAAAAAAAAAA
+
H?FDIC@@GDEEEBDF?@#@CHGCGGDEIG?H@IBBHAIADA@I?BEEIG@HHFGBFCCGHADAHDE?GC@ICHCCC<@@IBFBGIGDFEBCC(G.BD@@
@>chr21:9685108-9685162-0
CTCATACCACGCAGCAGTGTTCAGGCATCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
?D?HEFBFAFGGGB$CDEI?HE@HF-@H?A??C?GHDFADH@I@GI?C@GG?EIIAFGD?EFI@EFEEAHDGHGGH@@?FEABIEBFCEBHDFFAE@HHI
@>chr21:9685108-9685162-1
CTCATACCACGCAGCAGTGTTCAGGAATCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
FBH@ECDBAFFIIDGGIFGCFDGIED@??C?GH@GGFBC??GBHFDIGIB@II?@ADFFDDHHGBHBGGGBFDIAEEBICDHGCFHGDBFD?GH?C@@GD
@>chr21:9685108-9685162-2
TTCATACCACCCAGCAGTGTTCAGGAATCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
#B@DADE?DA,HFBFE@@HFAGFE@?GDBIGAGB?BHFC@G?F?@AA@HDBBI??IF@GC@DBEFF?F?EEHFDGGE@?FAC@AEHFB?DA?HCHCDEG?
@>chr21:9685108-9685162-3
CTCATACCACGCTGCTACGAGGGTCTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
IECHAAAHHH@FGEFBG@IC@EED@B@F?BFHBB@DGADGIC@EIGEE@ABHBF@IE?HEIAHCBCHEBAH@AE@@C@IACC@AG?ECEBCB@FHFECCA
@>chr21:9685108-9685162-4
CTCATACCACGCTGCTACGAGGGTCTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
@C?HEA?I@DDIH?EFAEAB@?EEAEDEEGBD@BI?EHEFAEGBBBAHB@@CDFCGE?CHBDIFEG@IHEGACCF@IIG@IIABAFHIIBEAC?@@AGC?
@>chr21:9685108-9685162-5
CTCNTACCACGCTGCTACGAGGGTCTGATTGTTGGTCACTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
EB?)?FD@GFD?@AFDCEDEDC+I@FIFGED@DBDIB3HGDCHG??E?IABCCD?AG@G@GBHEBE@CHA?GDIB?H?HHHDBHEECEC?IF?HHHG@D?
@>chr21:9685108-9685162-0
GAAGGTCCTCAGCAGTGTTCAGNAATCCTAAGTGAGGGACCAACAATCAGACCNTCGTAGCAGAGATCGGAAGAGCGAAAAAGAAAAAAAAAAAAAAAAA
+
BA?G??D@IDCAGG?BDEFCCA$CHGG@HGBEDIEH@?FGF@DCDDHBIHHBI/EAHEIBFBBAFIFEIDCAHEABDEGBGA"AC@FFHEGEBIBA?FIG
@>chr21:9685108-9685162-1
GAAGGTCCTCAGCAGTGTTCAGGAATCCTATGTGAGGGACCAACAATCAGACCCTCGCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAATAAAA
+
GEEFBGEBI@GGF?@EHBD?GIGIF@C?FF??FB?GCHIDH@FED?@>BI??HDF?H)?G?DHDHHBFDBCGHIEECBFBAFAEGFHFFA@AD?G$A@CE
@>chr21:9685108-9685162-2
GAAGGTCCTCAGCAGTGTTCAGGAATCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAANAAAAACAAAAAAAAAAAAAA
+
HIH??CCB?IEBDFCDI??E@EDCCG?@IGE?BCEG@?I@BABABFGGBGEDE?D?GDEFB@AFCBEEC?DFAFCC?I@3BE??8!DCIHFDAC@IAEDD
@>chr21:9685108-9685162-3
GAAGGTCCTCTGCTACGAGGGTCTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
IG?BGAAFG??@CEG@GHAB@?FDBHFGDGI@BCAIDIHAEIAHGGBDGAGEDA?BAIEFHICECBB@BIE?@F??BEIIAHIDGA?@CIFII@AFIGG?
@>chr21:9685108-9685162-4
GAAGGTCCTCTGCTACGAGGGTCTGATTGTTGGTCCCTCACCTAGGATTACTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
AD?BCAA@GFDGB@I?CDGHCABEHF??ADEHAD@@FHGI@,E?BB@@G.FHA?DI@BG?FEAAH@BCBBBHHFBFEEGFCDDCHEIEAAHB?EG?CFAB
@>chr21:9685108-9685162-5
GAAGGTCCTCTGCTACGAGGGTCTGATTGTTGGTCCCTCACTTAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
HFI@FABEGIDIH@CFBHACA@@FFBF@?HD9HHAHFBCCHAHGDEDGCEC@IIBCII@D?FI?GHHGEFEF@GCGEDIHGHBB?EC@BEI?HBGHGFIH
@>chr21:9685108-9685162-0
GCGGCGTACAGCAGTGTTCAGGGATCCTATGTGAGGGACCAACAATCNGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAA
+
?FIDIIBFC?CAECIHAAEF?G%DEF?DGIH@G@HF@E@CIEDDFDC(ADEFF?ACFCAIBGIFEFIHF@BGHHFA@EF@EB?ED@H?HHICFDFICBBD
@>chr21:9685108-9685162-1
GCGGCGTACAGCAGTGTTCAGGAATCCTGTGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAA
+
?FEDCCIIGFFIDCFDIDAIIE@CGB@I/F?EF?@IAA?@FDA?DGE?:I?@??@BGDAH@EDFDEAAH?GBHADIA@BDHFCFI@FCGACGGFD@CIEF
@>chr21:9685108-9685162-2
GCGGCGTACAGCAGTGTTCAGGAATCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGAACGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAA
+
BGCF??@HEHAAGEAEEEC@@???FHIDBDIF?HFIIDDECIACC?DIHGI@DG@G?DCDHECGA6FFBCGFHACGGGBDDI?DADBBI@?B@GCIIGHH
@>chr21:9685108-9685162-3
GCGGCGTACTGCTANTAGGGTCTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAATAAAAAAAAAAAAA
+
@CCE???EGGIGHH8"AE?E@EABHGDGC@CA?ICHG@EHI?HHAFEFC@EIGFGCAAH@DCF?HFFEAFIGFFH@DABIIB@CGB%E?@DHGGHEEHIC
@>chr21:9685108-9685162-4
GCGGCGTACTGCTACGAGGGTCTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAA
+
CCEGDADCAGBB@GDBDI@GHFCGCCDDBCCF@@AGAE?BCG?@CHFBGFBDFDDBA@?@EHAHB?@A@EII?GBIEFEABEFEEBGBIBGHGA@BBICF
@>chr21:9685108-9685162-5
GCGGCGTACTGCTACGAGGGTCTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAAT
+
FAFACFECIBGABADICCCCEHG?A@CB?C@GAGFFFGBCH@E@IAEHCC@CBHIAEH@CFAEBIHE@DDDBAHBEGAFDIDA?@?IEGD?BAFCIADA:
@>chr21:9685108-9685162-0
TCAGACGGTAATCAGCAGTGTTCAGGAATCCTAAGTGAGGGACCANCAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAGAAAAAAAAAAAAAAAA
+
EA@HB@FF@FEI@IGB??@E@CFIDIF@IHFCB?GBEFHCFGEGG5HGIIBGHFDEDIE@BCB?IHCCCDCBFA@?HGI@GIC=IHEEGC?HEI?GHAGE
@>chr21:9685108-9685162-1
TCAGACGGTAATCAGCAGTGTTCAGGAGTCCTATGTGAGGGACCAACAATCAGACCCTCGTAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
@?IACEIGCIBHEG?BCCBIGDHIBAI;HIGFCCIFF@IID@EEIGIFGCGB?DGGABIEEFH@GCF@GFFAG@BCAECI?GCGBEFH?IGEAECGBDB@
@>chr21:9685108-9685162-2
TCAGACGGTAATTAGCAGGGTTCAGGAATCCTATGNGAGGGACAAACAATCAGACCCTCGTAGNAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
?C@DFHIFG@FE0HHEHI,DBAG@AD?ABDAG?EG5A?BH@I@=HDABFEAEDCHHCFFH?A?2F?GDC@CECIE?AHFIE@H@BG?EBCG@F@@ADIDA
@>chr21:9685108-9685162-3
TCAGACGGTAATCTGCTACGAGGGTCTGATTGTTGGTCCCTCACATAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAACAAAAAAAA
+
B@?IEAD?IE?EEIB@?BAHC?HC@ABCGBDG?EEDH?EFIBBDE??CDHCH@@DIDFBGFD@GGED@?EHE@E@EG?BHB,DBG?I@BCC-G@HIFEA?
@>chr21:9685108-9685162-4
TCAGACGGTAATCTGCTACGAGGNTCTGATTGTTGGTCCCTCACTTAGGATTCCTGAACACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAANAA
+
AHA?IDGHC?ECIICGAE?HC?B6?BCGGBIGIAHFACH@C@@@EFDEDBEBFGBGFH@GC*@HDCFDHIA?CH@B@DDBHGDFEBGCGCHCHH@CD(F@
@>chr21:9685108-9685162-5
TCAGACGGTAATCTGCTACGAGGGACTGATTGTTGGTCCCTCACTTAGGTTTCCTGAACACTGCTGAGATTGGAAGAACGAAAAAAAAAAAAAAAAAAAA
+
DACB?GHFDIC??GGCBDBEHIII8ECB?FI?IDHIEEIAI@EDAF?FI%?@@C?@?GDGHFC@DHDDBE<IE@DHE2GEIFDCFHGHIE@DHEAAHEID
@>chr21:9685159-9685255-0
ACCACTATGTCAGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGTCGCAGTGGTCTGGAATCCAATGTGACAGAAAAACATTCCGACCA
+
EIDB?DBB@E?BHHAD@HIIA?IAH@I?FCB@EAE@DFH@?AEFAAGEHCEBC@C%CD?FADC1AHGDAADCFD4FGFEAEAGHGACCEACBGHDH?FCF
@>chr21:9685159-9685255-1
ACCACTATGTCNGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCCGNAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACCA
+
F@D?IIFGHA?=GAFBFCFEDHGBDGCAAEBC?GDF?I?HFCDGHF??AG@BAEHDDG)BEFGAIC@H?GBBIGFCCGGD@?@H?BACBCA@IBACIH?E
@>chr21:9685159-9685255-2
ACCACTATGTCAGCGTACTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCCGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACCA
+
AGGGFA@HAIG@HE?A7EECEDIFHHEIGBFF@CBIIDAC?CD@H?FACH?DBH?ADAGCIGAG??HDHIDAIBEI?FEHCIF?DAH@?ECAGBABAH?@
@>chr21:9685159-9685255-3
ACCACTATGTCTGCTCTGGTCGGAATGTTTTTCTGTCACATAGGATTACAGAACACTGCGGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCAGA
+
FFIB?ABIIDBEAEA$FBGDIG?HF@FDDBGDDHCGAGFCABAB@GA(@@@ICFFI?IC?IHC?DFCG?CA?ID@ABCGDIF?BHBGAFACEAGGAAEII
@>chr21:9685159-9685255-4
ACCACTATGTCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCGGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCAGA
+
DCC?FIG?ABI?GDHHE)DAEEEHA?IGD?B@F@HBDFDHBIHCAIH?HBGBAFCC?CAHI@FAC?BDEHIIHBHEC?B?C@IBHFDCCHGFD@@AEAE@
@>chr21:9685159-9685255-5
ACCACTATGTCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCGGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCAGA
+
HHF?AIDACE@DD?F@ECBEFII?I@HDH?FDG??BHICG@E?AIHDHGAGFIE?CBH?ADBCC@GBGD??GGAA?GHGHABIAHCACBIGF?@EIAGAA
@>chr21:9685159-9685255-0
CTCATACCACGCAGCGTTCTGAAATCCTATGTGAGGGACAGACATTCAGAACCCAGCAGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACC
+
@AAGFAFGGFHAICBCC?IBD@FH@HDGAIDDIGICDF@":@IEAGCDI@@G@GEHDDIFFFDCDEAEG@BFCE?DHAF@CAHGDAAIDD@FCHCAHACH
@>chr21:9685159-9685255-1
CTCATACCACGCAGTGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCAGCAGTGTTCTGGAATCCTATGTGACAGAAAAAGATTCCGGCC
+
@?BAHBBCCBIDBI1FBC@BGFGBEF?HE@A?IAEHEFI@AGHICAIFBFEIFIGI?BA@?FAEHDHC@@@IHEFAHDF@G?AEFDH@FA=HHC@HA3BE
@>chr21:9685159-9685255-2
CTCATACCACGCAGCGTTCTGATATCCTATGTGAGGGACAAACATTCAGANCCCAGCAGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACC
+
@AIEH@GDI@EFI@"HBBCD@C6H@EGFHABBICHEE?FGCDDH?FDEA?'EBF@@HH?HB:BBEBIDHG?DGHDIDC@BHCIDFBG@@IFAEE@G?AEE
@>chr21:9685159-9685255-3
CTCATAGCACGCTGCCGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCTGCTGGGTTCTCAATGTGTGTCCCTCACATAGGATTTCAG
+
III?C@2I?FGICGG3GI@CII?IE@BII@FHHEFGAEIG@HGI?EAGCIGGCCBGCFHE?EA?@IEIGGG>ICAC@+GDFFDAFC?FDCI?IEBAHIHF
@>chr21:9685159-9685255-4
CTCATACCACGCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCTGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCAG
+
AGIHADIBIEDBC@D@I?@ADCAEGGD?IFHFEEFG?IF?HIBHC?FGABECH@@GC?CDA@?FIACDEGGCIC?EFIF@G?F8FE@DA@G?@EEHHECH
@>chr21:9685159-9685255-5
CTCATGCCAAGCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCTGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTGAG
+
GH@E@1CAI,A?FH@F??GHFDGD@?D@EHAHGHCI?D@BBFAIDGGIHIADEFBH?AG@HBBF???FH@FDFH?GBIHFFEGFFGFGCBIDG@?GA$?@
@>chr21:9685159-9685255-0
GAAGGTCCTCAACCTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCCGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACCAC
+
G@AHDIIGGG@)C>@E?FH(F?B?HFIGHI@DA@FDGCI@?FGEBI?IFCHFHBDAFHCIFB?B@BGEDA?@?DFIAHGFCG@CABF?E???AFADHABE
@>chr21:9685159-9685255-1
GAAGGTCCTCAGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCCGCAGTGTTCTCGAATCCTATGTGACAGAAAAACATTCCGACCAC
+
IF@DBBBCIBHAFEFBDDFEHEEEFEBHEF?ABIEH@?HCBAFIAFIIH@BFIGE@DIC@@D?G?F/FBIEEFI?@HHB@HGBDCEGAGH?GEFGA@CEE
@>chr21:9685159-9685255-2
GAAGGTCCTCAGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCCGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACCAC
+
AAAGC@AC?FB@FI@@GDIEBBD?CAHABIBF@HHAEEI@BBFHAD??HGDECAFG?IAH@F@DECDBDGDDH@HE@IHBBFDB?BDIADGIIB7FHGDI
@>chr21:9685159-9685255-3
GAAGGTCCTCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCGGCTGGGTTCTGAATGTTTGTCCTTCACATAGGATTTCAGAA
+
CDHBDG@FHHGB?HGBGBBIAAGHGE@G@DG?@EEIEEBHICI@@GDAHFFGDGHBCE@BH@C@CDG@IDGIEHG?CCBID=B@H@CG?HCHIBAH@BID
@>chr21:9685159-9685255-4
GAAGGTCCTCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCGGCTGGGTTCCGAATGTTTGTCCCTCACACAGGATTTCAGAA
+
C@BHHFGE@FDBCAFDFIEE@@BE@F?IFB@@IIC@IAI@ADHG@EA???FHC@IGGDFEHAI?IEBH8AGIH@IDHBA??GDD?CE#?CA?BIFDEIGC
@>chr21:9685159-9685255-5
GAAGGTCCTCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAANACTGCGGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATCTCAGAA
+
ED@?FCI@CDGGFFBGIACAHHBAGFHHEB@A?@BFEA@FDFGBA@A@@CAF>E?@DB@G@BBDCC@FDFAFGHADD?C@ECCBGCAAFFG?B/A?@@C?
@>chr21:9685159-9685255-0
GCGGCGTACAGCGTTCTGAAATCCTACGTGAGGGACAAACATTCAGAACCCAGCAGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACCACA
+
B@@;@I@HDBAD&ECCEGBFF??HI@-@DICE@HHDCHHGBBDHA@FEBFBFBBFGBF?D@CCCCABBHBCCC??A@?BFD@EAD@?CAHGEDAEC?A@I
@>chr21:9685159-9685255-1
GCGGCGTACAGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCAGCAGTNTTCTGGAATCCTATGTGACAGAAAAACATTCCGACCACA
+
DGI??CBDHHFCG?@BBEGCCACDCHAIHICEHFHAGDCEBFAF?DADGEEI??A?IDB@.CEIGIGDEGHFABIIFHGFEDBAAEGF@?FICH@IHCEG
@>chr21:9685159-9685255-2
GCCGCGTACAGCGTTCTGAAATCCTACGTGAGGGACAAACATTCAGAACCCAGCAGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGACCACA
+
CA$FDBBBBDE@FG?DD?ECHFIDHA0?BEEECEACICG7E@HGAAGFE@FGEGGHGICGAEAIGCABBC?CGA@?CACFBCD@AEA?IHEA?DD?IEHE
@>chr21:9685159-9685255-3
GCGGCGTACTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCTGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCAGAAC
+
FCBB@AAE@G?BHEFI?HCEIAE?II?AFEI?GBHIDADEEFD;IDI??DFIB??IEA?A@@B@IAHDA?BH?@B@GEC?BBHGBE@IEGFHHFFCIDAI
@>chr21:9685159-9685255-4
GCGGCGTACTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTNCTGCTGGGTTATGAATGTTTGTCCCTCACATAGGATTTCAGAAC
+
IIGDCHDIH@EE@?GCBGACGHIEF?IFIECED@?H@I?EAIACHBECIAEADEA:DCGHIFF?BC(IGGAACAEGCCAHCG?HDFAFGC?BA?HIBEGI
@>chr21:9685159-9685255-5
GCGGCGTACTGCTGCGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCTGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCAGAAC
+
IIHGG?HEGEBD@B#DF???H@?GAGII?BGIEHAFAGHI@EII?B@E@GHABFFIFBBD@EGEAIHHIIFHCH@@?HFGDDEEBGACIDGH??G@IABI
@>chr21:9685159-9685255-0
TCAGACGGTAATCAGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCAGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGAC
+
@GEII@HIFE?@HC@EFIHFH?FEABHEAH?BGDCCHII@BHBICHGAHBH@DIA@EHBIIHHHGABG?!CCIGF@GIH@BEFCBGHGH@AAC@?@GIED
@>chr21:9685159-9685255-1
TCTGACGGTAATCAGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCCAGCCGCAGTGTTCTGGAATCCTATGTGACAGAAAAACATTCCGAC
+
EA&DBCBDEBAFCA?DE@DBIH@BEGDBHE@BA@DF?ECEBAIGABIBEGGE?AEDB@DD@DHEBF?G@IDDIA@BAFE?DGIF@DABGBFEGEAA?EAH
@>chr21:9685159-9685255-2
TCAGACGGTAATCAGCGTTCTGAAATCCTATGTGAGGGACAAACATTCAGAACCNAGCCGCAGTGTTCTGGAATCCTATGTGACGGAAAAACATTCCGAC
+
FABA@AA?D@EB@FC?AHF@F@CDCHGDCBEICCEAD?CCHHFH@GBHABGA?C4AFCHBGIEHI?CF@@A??ACD@E??DBGE0D@CGACH@GIHEGAE
@>chr21:9685159-9685255-3
TCAGACGGTAATCTGCTGTGGTCGGAATGTTTTTCTGTCACATAGGATTCCAGAACACTGCGGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCA
+
?A@??EIEEIHAFCIC?G@EHG??AFDDACGFHF@A?C?BFCECEHBBCCFH@C?GCAAGACB?FCBGA+HEAFCIBA?CIECFIC@GHGFBEDFC?ADE
@>chr21:9685159-9685255-4
TCAGACGGTAATCTGCTGTGGTCGGAATGTTTNTCTGTCACATAGGATTCCAGAACACTGCTGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCA
+
AHHDC?CBDFHCAAHGCGIAE??EBDDBF?BG2DBHE?DAECGHFICG@EGI@IDDD@H?DABAA@B@FH@HHHHAED?CI@@CHCIBB?@BAHII?@II
@>chr21:9685159-9685255-5
TCAGACGGTAATCAGCTGTGGTCGCAATGTTTTTCTGTCACATAGGATTCCTGAACACTGCTGCTGGGTTCTGAATGTTTGTCCCTCACATAGGATTTCA
+
D@CA?AFHDGACG'DEEAADC?ED'?F@B@CH@HA?FDBIEDID?EAGDHC&EAEDDBE@IFACFDF?IEI@?C@IEHAABCFCAID@FAAFD?@C?CCF
@>chr21:9686159-9686258-0
ACCACTATGTCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCAGA
+
CEICG@HE???I@C?A?D@AIBIBICBEHCBCAGGHACFHC&ECH@?BHHAICFEBDCIF?H@GB4GED?DGDCAEAAG@ICDCBFHBF@CHFHBAEII@
@>chr21:9686159-9686258-1
ACCACTATGTCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCAGA
+
GD@DFHAD?HF@CAEHGA@CDD@C??I?CDBA@EGBIAAGFBDHHF@@DCD@AF?IDGIHCIIEHEEDB?@?FE?F@?CDEGGEGDEEIHFEGDBGD?DD
@>chr21:9686159-9686258-2
ACCACTATGTCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCAGA
+
CGAAABCACBC@DCGEAAD?CICGFBIFD@FHDBAGCDIAEH?AHHACEI@AI?F?H5BDGA@AC?BGCEAFIEI?A?AEIACF?I@?IAH@C?@CECEH
@>chr21:9686159-9686258-3
ACCACTATGTCTGCTGTGGTCTGAATGTCTGTCCCTCACATAGAATTCCGGAACACCGCTACAAGGGTCTGAATGTTTATCCTTCACATACCATTCCAGA
+
@@C?GD@IGEGDHFDCFCHHHD?GI?@?6GAED@@HEG?HDHDIH@@I@BHHEHBA%FICD?BHI@D@?G@DCI?@ID.HEAEI?GEHBIIAIGICDDIB
@>chr21:9686159-9686258-4
ACCACTATGTCTACTGTGGTNTGAATGTTTGTCCCTCACATAGAATTCCGGAACACTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCAGA
+
HIC?DB?CEIBD=DI@H?HD,ADCADIIAIBEE?DDH@G?HHHBE?AII@DAFBAHCBI@F?HHI?FB@GFGIIE@F?GGF@BB?@AFHA?FFDEG?AFH
@>chr21:9686159-9686258-5
ACCACTATGTCTGCTGTGGTCTGAATGTTTGTCCCTCACATAGAATTCCGGAACACTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCAGA
+
CDDHACEHICBBGIE@BFCCFFEH?DC?HIEBFGCFBB?@CFIIHDFC@HAG@HDCADHGBABI*EB@BAIIB?BEHDDCI@AE?C?IE?@CHHFEHAAG
@>chr21:9686159-9686258-0
CTCATACCACGCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCAG
+
IDAGICECFCEA@ABD?D?HHH?A?IE@FHGBF@FBGEF?IEHIDBCGHHHBHE?F@FCFD@DG@G?FIIG?DB?FECCH???CCGA@HCH?@G?@FG?G
@>chr21:9686159-9686258-1
CTCATACCACGCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCAG
+
CGFBBB@BECBGCECBIGE@EACFF?BH@I@GGFGBF?FIFIE?A?GCDAIAHF@?A?DEFEACI?BFCFGCH?DDHFHBAE?HEIBFGEG?CEF@HFE@
@>chr21:9686159-9686258-2
CTCATACCACGCTGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGAAGTGTTCCGGAATTCTACGTGAGGGACAAACATTCAG
+
DAH@H?FABFDD$@IH@I@B?A?BHG?DIHIHFHHHB?EGE@ADACBECDBHCICCHGIGBD)BE@C@EF@H?GGAFBEA1?I?IABFEHC?@FCFGC@?
@>chr21:9686159-9686258-3
CTCATACCACGCTGCTGAGGTCTGAATGTTTGTCCCTCACATAGAATTCCGGAACACTGCTACAAGGGTCTGGATGTTTGTCCTTCACATACCATTCCAG
+
GDF@HGCCEFFGB@BHD*FD?GDDHEHBGADC8IFCAEIAEACID?BDFG@?AFI@I@HEHIDA?FCDI@D@7DG@IAHGBH?EBDFDECF?H?GFCIFE
@>chr21:9686159-9686258-4
CTCATACCACGCTGCTGTGGTCTGAATGTTTGTCCCTCACATAGAATTCCGGAACACTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCAG
+
CAABE@EEEE?@IBEDFGHCDCFBGHCCHEEBFDICIA?G@GEFF@@ADI@?@@IDIDB@?GEEHBH@DDAGAC@IEDCDB@@FHED@AGAE?H@C?FHB
@>chr21:9686159-9686258-5
CTCATACCACGCTGCTGTGGTCTGAATGTTTGTCCCTCACATTGAATTCCGGAACACTGCTACAAGGGTCTGTACGTTTGTCCTTCACATACCATTCCAG
+
HAB@EGACCBBB?GGHI@EBDFAIBDIE?HC@HFBD?HACEH4A@FIBICEA??)E@ADG@HHIDIIFFA?E0?+@CHFDGGHHGIGHC@?A?DEIH@BI
@>chr21:9686159-9686258-0
GAAGGTCGTCAGCAGNGTTCTGGAATGGTATGTGAAGGACAAACATTCTGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACANACATTCAGAC
+
D@IAI@H,>HBG?DH1FIEDGEDCGFAEGADB@0GCCCG?CDIHGCGC>C@DFD@GBDDDF@?CDE@DDCD@IBGC?BAB?FCCCCEGB#HBEHCIHGE?
@>chr21:9686159-9686258-1
GAAGGTCCTCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCAGAC
+
@BF??@D?DHCFC??@BGAAEFADECBCGEC??DFBH@GC@G@EG@GH?FHGHACHDHFDBEB?GIFFIEGGB?BDFGEGBHFBD?G@AHBBI??@E@?B
@>chr21:9686159-9686258-2
GAAGGTCCTCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCANAC
+
EBABFIAEAFCG?DF?ABGCIEIHFEAFF?FIIEAF@EGDEGEFIE@@FHDCEABE?D?BI@F?EDA?@ECEIDDI@C@HF@?IHHCCDCIBACHI?6IC
@>chr21:9686159-9686258-3
GAAGGTCCACTGCTGTGGTCTGAATGTTTGTCCCTCACATAGNATTCCGGAACACTGCTACAAGGGTCTGAATGTTTGTCCTGCACATACCATTCCAGAA
+
?D?EIF@@5HGDIICACHI?AHCH?EDAB??DBGEFCCBFCD*ADFBDFBIGEBEHGECD?IAHAE?BI?AHD@?HIDDE@C2BIA?I?@HAFCBEAEC@
@>chr21:9686159-9686258-4
GAAGGTCCTCTGCTGTGGTCTGAATGTTTGNCCCTCACATAGAATTCCNGAACACTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCAGAA
+
BD@CED@ICIGIB?BGGBGHA?HI9BHBDF>?I??I?EBH??AAF?BD)IDBGDHEICDHIGIC@FACBF@CBFI?BCID?II??ECEBAGIDEAGFA??
@>chr21:9686159-9686258-5
GAAGGTCCTCTGCTGTGGTCTGAATGTTTGTCCCTCACATAGAATTCCGGAACACTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCAGAA
+
FIDCAD?IBABEIDGHBGGEGHCDH??I@I?E?CE@IBDHA?FF?HAEBDEGA?EAGFECD?BAG??EB?DCFI@G?CAAGAGGFIFC@CD?BFAGAFCE
@>chr21:9686159-9686258-0
GCGGCGTACATCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAATGTTCCGGAATTCTATGTGAGGGACAAACATTCAGACC
+
C@FGI?ICDI9AIFBCH?ADBDGGBDHACHB?DAFGBBE@ICBEHF@I?AE&@BHEC?ADBHECBD@?CGHB@GE?DABADG@FAGBG@CGDA?CH??BB
@>chr21:9686159-9686258-1
GCGGCGTACAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACATTCAGACC
+
IFGCDBBCEEIE?CGFBCEFEGIFGFHE?EADCEA@CHH?FEFIGDDFCFB@@?CGFBFHCAEIBB?GGFCACC@?IEHIAHCD?AEID@I?AFD@@@AI
@>chr21:9686159-9686258-2
GCGGCGTACAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGCAGCAGTGTTCCGGAANTCTATGTGAGGGACAAGCATTCAGACC
+
?IDIHGBIBDGD@IE?@?EDEHABDFH??HHIAB@D@@IFBBBBGG@EE??BBDDD3EADBECBGDI@DFFH,?EHEDGAGCBF?@IED!BIC@FDDEGI
@>chr21:9686159-9686258-3
GCGGCGTACTGCTGTGGTCTGAATGTTTGTCCCTCACACAGAATTCCGGAACACTGCTACAAGGGTCTGAATGTTTGTCCTTGACATACCATTCCAGAAC
+
F?I?AACE@HEEBGGCBIG@DI@?ADAF?EH?BEHDBE)??DACDEH@FDAGA@A@EC?@E@HCIABD?EFFEH@IGEHCFD.B?DEGEIHHGGCI@B@A
@>chr21:9686159-9686258-4
GCCGCGTACTGCTGTGGTCAGAATGTTTGTCCCTCACATAGAATTCCGGAACATTGCTACAAGGGTCTGAATGTTTGTTCTTCNCATACCATTCCAGAAC
+
BE9CI?FE?HIIC?DEFD?=B??FIIEGGCFAHDE@ACEFFCADH?DHCC@F?HHDBHGIDA@BEGEHI@?F?FCICA#HGA@$CGCBEFGFACBG@HCA
@>chr21:9686159-9686258-5
GCGGCGTACTGCTGTGGTCTGAATGTTTGTCCCTCACATAGAATTCCGGAACATTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCAGAAC
+
ADBEFCIG?BBIEF?AA@@F???ECEDAEH?ABC@IDC??BDH@D@F?BIFC?AEGDBIE?CACIAACA@IGG@@D@ACGFEDGCFAGBFHBCDGF@DDI
@>chr21:9686159-9686258-0
TCAGACGGTAATAAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAATGTTCCGGAATTCTATGTGAGGGACAAACATTCA
+
AE?HH?EI?GIE2BHEDDBEF?GAEEDII?FAFBH@@B@?BAG?@@HHCF@BBF@HEFAHAC@IEAFACBIECGAA@@G?@DDACHHCGCH?BBIIBIAI
@>chr21:9686159-9686258-1
TCAGACGGTAATCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATTCTATGTGAGGGACAAACNTTCA
+
BDICA@A@DB?GG@HIA?C?AH?HAH@IFIH@H@FAAEBBFDBBFE?@@DIGCDHGHBEBEDE@ABIFI??C?EBAIDH?FABIGIAGIEIHEA?2HEGB
@>chr21:9686159-9686258-2
TCAGACGGTAATCAGCAGTGTTCTGGAATGGTATGTGAAGGACAAACATTCAGACCCTTGTAGCAGTGTTCCGGAATACTATGTGAGGGACAAACATTCA
+
C?@D@A??DIGFIABHIIAEEGDGAGC@@GDE?C?BGA@@E@HIH@@GGBI??BFCBBEIIEABHFDE@FDEDCF@B=IH?GGHDDFFDIGAEIFIDHCD
@>chr21:9686159-9686258-3
TCAGACGGTAAACTGCTGTGGTCTGAATGTTTGTCCCTCACATAGAATTCCGGAACACTGCTACAAGGATCAGAATGTTTGTCCTTCACATACCATTCCA
+
DAI?ACEHG@G/BGIGAFCF?EACABBCAII@HED?FCIEIFGDIB?GHDGIECCFAFIIIDAHGECI&BD2FHG?C??BHHC?EDCAHFBII?BIEEAA
@>chr21:9686159-9686258-4
TCAGACGGTAATCTGCTGTGGTNTGAATGTTTGTCCCTCACATAGAATTCCGGAACATTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCA
+
HCFG@DAIFDICBG?FIECFCA-?C@GBHBIIFIEACECEFFBCCGGC@IBDACEGHBCFFIF?BAE@HBGCGF@@@GIFHAHH@HA?EBF@AABGFFAI
@>chr21:9686159-9686258-5
TCAGACGGTAATCTGCTGTGGTCTGAATGTTTGTCCCTCACATAGAATTCCGGAACATTGCTACAAGGGTCTGAATGTTTGTCCTTCACATACCATTCCA
+
DHC?DBCEEIEDCHICABH@@?G@@AC?@?BB?@CFC@2@H@DBAFFAAEC?BGGI@EIFBAFEF?EBF@BE@AAFCF@BDBCIE@HGH@AFAEHEHCFA
@>chr21:9686255-9686402-0
ACCACTATGTCAGCAGTGTTCTNGAATCCTATATGACGGACCAACATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGACACA
+
CI@?DE?GFCF?@@ECHBEDBF5E@ADFB@DIH@BH?DCICCBABIEDB@?FBA@HFCHIB?BCHIHGHHBAG@IGIFGEHIIGI?@CHDCFIFGHG?@C
@>chr21:9686255-9686402-1
ACCACTATGTCAGCAGTGTTCTGGAATCCTTTAAGACGGACCAAGATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGACACA
+
A@FE@D@ECHCE?C@DGDHAHFABFHB@B?$HA;DBDF?F@?E@+EG?DC@@IACICFBGI@FGBHICB?FAE@HFIHDHEIFE@I?IGE??FIAAIFCA
@>chr21:9686255-9686402-2
ACCACTATGTCAGCAGTGTTCTGGAATCCTATATGACGGACCAACATTCAGACCCTTGCAACAGTTTTCTGGAATACTAGGTGAGGGAGAAATAGAGACA
+
@C@@DIB?BEDHF?BFIA@DIDGEDI@??GC@ACAFBIDDG?E@ICAEABFBIICGIAAIEFEDC2IGDE@@B@?ECGACFHFHAFBEBFGFGH@@>AGB
@>chr21:9686255-9686402-3
ACCACTATATCTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGTCTATTTCTCCCTCACCTAGTATTCCAGA
+
BBC@BFBA0ECIIBHCDEHCFBIIGCI@IBI?E?FFIDGGED@DCHC??E@AFAICB@F@@CGFIHIGBIGEBF@GCGDEHCDFGBADFBBBFEEICIAF
@>chr21:9686255-9686402-4
ACCACTATGTATGCTGGAGTCTGAATGTTCGTCAGTCACATAGAATTCCAGAACACTGCAACAAGGGTGTGTCTATTTCTCCCTCACCTAGTATTCCAGA
+
AFIA?BD@DA7DBICBFE?@CFCEEAGCI(?@D??@A@GIBAABGIBEDGCFFD?EIHB.CHIC@CC?HBD@I@CEA@ADE?ADD?GDICIE@?)?DAEC
@>chr21:9686255-9686402-5
ACCACTATGTCTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGTCTATTTCTCCCTCACCTAGTATTCCAGA
+
HEH@FB?E?BBC??DIG@BDHHBG?BBGGCEADGAH?ACDHGAACC??CEFDG?CCFHAFEBBC@EE??IAH@@ECHIEEDAC@GHEACACCEFIDIDIA
@>chr21:9686255-9686402-0
CNCATACCACGCAGCGGTGTTCTGGAATCCTATATGACGGACCAAGATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCAC
+
G(EC?EGDHIAEIHI<EHFCHHIEFAF@CEBIIIH?IIDIHADH?0@@CGI@C?@DDCFEDBAIHFABGFG?EAIDDI?@FDCGCFC?@DAH@IGBCECG
@>chr21:9686255-9686402-1
CTCATACCACGCAGCAGTGTTCTGGAATCCTATATGACGGACCAACATTCAGAACCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCAC
+
IBGHAD@G?@EBEHGF@A@CEG@AGHDF@IABG?AFHG?@CFIFBGDEADGHH8G@H@CCAD@I?EHEBCH?EIH@@FCFCE@BFBHADHEBC@?EGBHI
@>chr21:9686255-9686402-2
CTCATACCACGCAGCAGTGTTCTGGAATCCTATATGACGGACCAACATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCAC
+
EIGGBBCGG@CF?CBBDCDFGHFDCAHIA?I@G@CA@HCEAEIBICEFE?BAIICCIFBI@EBE@FHAHBEIIDG?DBI@FHD?F'FBCDAHI@GGEEB@
@>chr21:9686255-9686402-3
CTCATACCACGCTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAC
+
?@ADIGEBDEADEHH@BEF?FGGI@ACHAFEFFFDEGIAGFIDBEHBDA@CIH@?CEHG@GBGGC@EDGFF@GIA?DCGGFFIE@GI@HDBB@DICBB?!
@>chr21:9686255-9686402-4
CTCATACCACGCTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCAAG
+
CHEHDEI?HDFBCGF@IF?IHDEDAHGBGHBHAECGC?I?@+??GIGH@EFEB?CA@E@IGBDBD??@@GCHEDF@GH??FGBGB@GHGB@@DH?GD'BA
@>chr21:9686255-9686402-5
CTCATACCACGCTGCTGGAGACTGAATGTTTGTCAGTTACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAG
+
BFG?FB?DHCGGEH?AHEBE<FAI@HCEH?IDIFFIE6IFE!@CHEHCBAA@G@@A?AI?@B?EFBDDCEBBGIGHCDIBFFHIG?DCHGEFEFDECFHA
@>chr21:9686255-9686402-0
GAAGGTCCTCAGCAGTGTTGTGGAATCCTATATGACGGACCAACATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCACAC
+
DGEG?GFCADE?HHFI?FH&D?IH?IHDA?ADA@BHDICGA?FFACD@CEA?DI@@ECH@HFHH?AFCHDGEGIBH?G?IIGIFIHDH?CIFH?B?CIAI
@>chr21:9686255-9686402-1
GAAGGTCCTCAGCAGTGTTCTGGAATCCTATATGACGGACCAACATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCACAC
+
I@ICF@AG@GCAB?@?AIC@FFHIBEHBHEEI?I?BEIAEEC@E@F?E?AAIE@IC@HFBB?AEBEIE@E?CAEHEHIIBAF@GF??CFEI?EA?HF?H:
@>chr21:9686255-9686402-2
GAAGTTCCTCAGCAGTGTTCTGGAATCCTATATGACGGACCAACATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCACAC
+
A?BH0FBIG??GEHAEI?ECG@D@EFA@?DBEIB?CEG@CAHAD?EEEDB??@BG@@DEFGGHEEHDGBHBIE?FEFC?GIAFGDEECCCFDHFCDCBBE
@>chr21:9686255-9686402-3
GAAGGTCCTCTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAGAA
+
B@?DBIEDGEFI@?DGBBHBBC0B?@FFGAIEGCEFBAAF>HF?BH@IADDDAE@EFIHE@E@C@C??CGE@HGG@IEEGGGGFG?EAAAF@?DIF@GDI
@>chr21:9686255-9686402-4
GAAGGTCCTCTGCTGGAGTCTGAATGTTTGTCAGTCACAGAGAATTCCAGAACACTGCTACATGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAGAA
+
GI@GGCGIAGGI@@@GHH?ECE?EICFGEIAE/EBA@E@%GAHGDD?DI@ECHA@?EDEGCH#FACEEFAHEEE?GGHD?BGEB@CIHCA@GCBHHGCEF
@>chr21:9686255-9686402-5
GAAGGTCATCTGCTGGNGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAGAA
+
B?A@B?A3GEHIG?HH0FHGHF?@EGBDIEBCDABB?AHCAAFEC@BCBBHE@@ECF?AB0@C@FBHCIIBHFF?@HDACHHEI?FHEHG@ICCCHGHHC
@>chr21:9686255-9686402-0
GCGGCGTACAGCAGTGTTCTGGAATCCTATATGACGGACCAGCATTCAGACCCTTGCAACAGTGTTCTGGAATACTAGGNGAGGGAGAAATANTCACACC
+
AAEDG?IIHCIICBDEI?IC6GDICBFG@II@C@@BBHB?G/@CAHCG?DGE@ICD@ECBAEGEGDAIFIHBHFH?DHI$AABABCC?BG/?&@IDFIFF
@>chr21:9686255-9686402-1
GCGNCGTACAGCAGCGTTCTGGAATCCTATATGACGGACCAACATTAAGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCACACC
+
CEA0AEH@?FDBDH/AAAIDGBDCG@FCIGHB@H@HCCEBGEDG@@3BHEGBAHG@IIF@FHHGHF?HDHBC?@E?@GDABC@DC?ECAAGCFICDC?BD
@>chr21:9686255-9686402-2
GCGGCGTACAGCAGTGTTCTGGAATCCTANATGACGGACCAACATTCAGACCCATGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCACACC
+
AC@@BHFAECBCI?@DEIAA?BAHEFBHI1BGDAEBI@?BI@DGAADBBHDDC<@HCIFBDG?GFIACFFEBDBADCHAF?BBA?G@H@B?/?I@HBDAD
@>chr21:9686255-9686402-3
GCGGCGTACTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAGAAC
+
?BA-DG@DHE?EHHGD@@IHCFCIIIBI?D@HCCHCC@ID@AC?GHB0GI@AECIGBIA?BCEDIG@CCADCFDC@?ACGCBG?FD@AFFDDAGDIGH@G
@>chr21:9686255-9686402-4
GCGGCGTACTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAGAAC
+
HF?GIIHFFD?EHEDGG@EDAFFGICGCIIFA@@F@IBBFBEIHEFIDIEGCBGDBCACHEEC@IEGDCCBIECDCHG?C@GE@??E?AIGBA@DAEGHE
@>chr21:9686255-9686402-5
GCGGTNTACTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCAGAAC
+
F?AA;;A?DGIDEIABFBHD?IB@IFEA@G@E?G?AF?FIGCCDDDGC@GAHEAIIEDAIBAAHGGBEFE@GHF@ABGAAEBI,CCAG@GFEEECDCBGB
@>chr21:9686255-9686402-0
TCAGACGGTAATCAGCAGTGTTCTGGAATCCTATATGACGGACCAACATTCAGACCCATGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCA
+
FHE@?CIEIAHFA?HHFAADBFIHC?DGAGGHB@A@D@@@HBDECCFFFHAGIFAE@9AA?DEHGDBCE@BHC??CEDHBHH@GEDBBBHB@FIGFIAIF
@>chr21:9686255-9686402-1
TCAGACGGTAGTCAGCAGTGTTCTGGAATCCTATATGACGGACCAACACTCGGACCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCA
+
IG@CDBH@?@0DG?ABD@EFCHIHECI??@?FF@AC@B?ID@IFHADA;AE2HIHF?C@@GAB??BAIIEH@AIGDFIIHIIEA@E?EHIAGEDA.?B@?
@>chr21:9686255-9686402-2
TCAGACGGTAATCAGCAGTGTTCTGGAATCCTNTATGACGGACCAACATTCAGAGCCTTGCAACAGTGTTCTGGAATACTAGGTGAGGGAGAAATAGTCA
+
HIDAD?FGGF@IDF@BAID?GFF@BGECFDGH0@AF@AB@A@HEEA?CEHAHCF;@HDD@EF@AHDCGFEDIGFI?GFC?C@HFCGIACFG?HBEBDA?B
@>chr21:9686255-9686402-3
TCAGACGGTAATCTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGATACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCA
+
G?CGDGBBIH?G@FDGBFICEC@FA@BGFHCFBDEIBII?BDEG?@AIHEH?FAG?@IEH<BD@IEHCHHIHHI?BI?IIACIGFCHGCIHAGIGDDDID
@>chr21:9686255-9686402-4
TCAGACGGTAATCTGCTGGAGTCTGAATGTTCGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTAGTTCTCCCTCACCTAGTATTCCA
+
BCB?CFGBAIF@@FCGAEHEIGDBBC?ECIF'C@IIBDIHDEI@F?AEA@HCBDB?ACHAEDBGG@DH@@@?AFACH.E@HI@A??A?BIAA@ABH?ADF
@>chr21:9686255-9686402-5
TCAGACGGTAATCTGCTGGAGTCTGAATGTTTGTCAGTCACATAGAATTCCAGAACACTGCTACAAGGGTGTGACTATTTCTCCCTCACCTAGTATTCCA
+
DCHCFCIF@FHEID@BDAFEHH?HDCEHBDCDDF?BAH?AIB?@AEA@HFCG@?CHGDFHEHFAE?BGH?CAHEAAHE?FDDHGADG@AEFH@ADFI@EC
@>chr21:9686782-9686881-0
ACCACTATGTCAGCAGTTTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGAGACAACCATTCAGA
+
DIIABGHBIHHGBF@?G>EGI@FA@GGGHIBIF?@EIGAIF@?@@EHGFBFGIBGAAIHIE?ACEHGIGHCEHA@CIHDADAH?H:??BAFCHCCA@FCB
@>chr21:9686782-9686881-1
ACCACTATGTNAGCAGTGTTCTGGAATCCCATGTNAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAGA
+
FAFC@@@D?B.?GHF?E@BGB@@EFAHE@AICEB4IE@CB@@C?DIDBAF@?A?GH@AD@IAIBBBIIDFDDF?EB?HE?D?BG@HBCBAFAGGEE?I?E
@>chr21:9686782-9686881-2
ACCACTATGTCAGCAGTGTTGTGGNATCCCATGTGAGGGGCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAGA
+
CC@DEEH@IEDIFGBFHDIC+A?@"DI?FDHAEDAE?IA+IE@?EHEGD?EIFEEGI?EAECBDF@BFCAF?DFC@HGGGCFFD@AGHA@FB@EFEEAED
@>chr21:9686782-9686881-3
ACCACTATGTCTGCTGCAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAGA
+
HAH?DDABIDEEDDEDB?D@DA?E?GDAC@?IBIAG@CI?H?FBE@FEA@CEHFIIEGAEDCA@HCFBHDDAEEFH@A?DIA?BHAFD@ICHHAAFA@?F
@>chr21:9686782-9686881-4
ACCACTATGTCTGCTGCAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAGA
+
CAGFAGHHI??@C@GIDC?HGIADFIAAB?CDHFBIHCDGHIHBFIIGDFCFEA@?GIAIGH?E@IBBAHIDHAB@?@IIIADCFDDGA?FGIHHIABG?
@>chr21:9686782-9686881-5
ACCACTATGTCTGGTGCAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAGA
+
ADCEFDDIGA@DF:BH@@GH?DIFADC?B?GED@BBECAGDG@D?B@GBHF@BCBBCDBBEAGC?IEDE?DAC@AEC@BEFHEAFCCEF?DI@GFGFDGA
@>chr21:9686782-9686881-0
CTCATACCACGCAGCAGTGTTCTGGAATCCCATGTGAGGATCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAG
+
DAFEID?EGHBFBHIFAGEFCHIA@AHECEGAH@IBHEI<@ACIFGDH@CIHFCCHGABD?AIIB?FDIAEFEGA@?DH@EBEIBHFAFIEACH?FDH@B
@>chr21:9686782-9686881-1
CTCATACCACGCAGCAGTGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACANCAGTGTTGTGGAATTCTATGTGAGTGACAACCATTCAG
+
A@AIF?FCB@D?@F@@EA@IFIID?BEHE?F?HDCHABG@F?AD?GGIEEFC@H@FAECEH'G?IE@IB*?HGD?BHACBD?FGHG?GCHFDD@@?I@I@
@>chr21:9686782-9686881-2
CTCATACCACGNANCAGTGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAG
+
BE@EFAA@BIG!D3H@DDG?ICDBAH@?HFGHIDDFFGB@GDDID?D?CEDDIEHDFAGA?G?B?@BEFDF@DDGHBED?AEGCE?CCCBGEIHH?E?HE
@>chr21:9686782-9686881-3
CTCATACCACGCTGCTGGAGTCCGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAG
+
HBA?E@IGB@DBGIGED??@IF!DBDE@HIHFDCHCI@@IBHD@IAFDAEBAFBIBH?ACCHC?AGBGFDGICGB@D??ECI@FGBAD?AE?EGCCHBI@
@>chr21:9686782-9686881-4
CTCATANCACGCTGCTGCAGTCTGAATGTTTGTCACTCACATNGAATTNCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAG
+
CGDGCD6G?IDEGFDHD@AB@F@?DA@H<GBEBIG@FABIDF3DDECH<CBAHC@BE@BHBHG@AHGE?AEBEACGCAA@CFCB@CAA?IGFFCAHEFAI
@>chr21:9686782-9686881-5
CTCATACCACGCTGCTGCAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGNTGTGAGGATCTGAATGTTTGGCCCTCACATGGGATTCCAG
+
GIC?HIC?IBICID?AHDGD?FH?DCHH@??DIIDFC?ADACHCEGAHC?H@GFIGEFH/E@CFI?AFDGGFDAC??DF?&BHA?A@HGHCEICCHIIGF
@>chr21:9686782-9686881-0
GAAGGTCCGCAGCAGAGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTNGAATTCTATGTGAGTGACAACCATTCAGAC
+
C?HDIHCE0IA?AA@>DEDDED?I?@?DGBGHHIIGDGHIGCHGEBGB@C?GDHFAH?E?@BADAAAFA;CEGIBCAABGD??H@EGAECCBIAGGIGIA
@>chr21:9686782-9686881-1
GAAGGTCCTCAGCAGTGTGCTGCAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAGAC
+
BFAEHBB?EDIFACHECC%ABE8HFHGB@GH?DEGCFFC@@CFE?FD?HIHCHHFDE@CDEAGBCACDBFDBFFGGGFIEGCG??F?@IFIFIGGFE?EG
@>chr21:9686782-9686881-2
GAAGGTCCTCAGCAGTGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAGAC
+
FIDFHFA?D?DHA?HBFICCH@GGIICFFICGI@GHEIGHICIBD?HBGFADAI@DAFCAC@D?HF@HBIE@C?GDFHH?E@HI?FAAFCEGABG?IHGF
@>chr21:9686782-9686881-3
GAAGGTCCTCTGCTGGAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAGTA
+
EFHBD@FIECEA@DFHBIGGCADGEGCFIFHH?@EGHFEIBHIDAA@B?ADA@?IIBAF@?CAIEB@@?FGCFGCBI@ECHEIDHHBGFA@EG@FCDF$G
@>chr21:9686782-9686881-4
GAAGGTCCTCTGCTGGAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTTAGGATCTAAATGTTTGACCCTCACATGGGATTCCAGAA
+
@IDHIFBIBFHG?@FHB@?AC?CDBEHF@EAAFFEHEFE?BEADCA@A@@DCIHDB@I@@F,DFIEFFD/IC@DHGG??IFFB?ABIGEFB@DEGCDFCA
@>chr21:9686782-9686881-5
GAAGGTCCTCTGCTGGAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAGAA
+
IGFHCCIH@IIEI@DD@IID?CGH??CDCBHFIGAFGCFGFIFIACCAHCIHCACEEC@@@D@@BGA@DBI@?BGEGHHEI@IFEA?@@ADFF?FEG?HI
@>chr21:9686782-9686881-0
GCGGCGTACGGCAGTGATCTGGAATCCCATGTGAGGGTCAAACATTAAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGNCAACCCTTCAGACT
+
?GICBEHDA>G@ED?@;GCGF@GCACDGF?HBCIH@?IHDGADFG@3ABGHFID@?DHGGFAAEFDB@?FFACACCHGECIHFAC>BIDHC8A@ABFIH@
@>chr21:9686782-9686881-1
GCGGCGTACAGCAGTGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACGGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAGACT
+
CFADBCCIHI?E@CHIFC?GBDIDI?AGBBIIAD?GGGDFHC@EFEDHCI@EAECHF;G@C?ICCAE?GI@CDBE@FBGIFI?HCBBDH@IAHBCAEC@F
@>chr21:9686782-9686881-2
GCGGCGTACAGCAGTGTTCTGGAATCCCATGTGAGGGTCAAACGTTCAGATCCTCACATCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCAGACT
+
@IIDDEEE@@EIBCHEBEI@IA??EIDB@C?EFHCD@@GIABA2@II@@G@EEFI@DC9?CC?B@IFHFAEAGGFG?BHH?DHBDGGDGGHFI?EIHG@G
@>chr21:9686782-9686881-3
GGGGCGTACTGCTGGAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGNTCTGAATGTTTGACCCTGACATGGGATTCCAGAAC
+
G4GD?ED@I?DH@AAHCH?DCHFGH?GED@?GIEIEG@BID?BIHABIDFAC?H?GFB?BIFBA4C@ACHD@GD@BHICHBF"E@GFIEFA%DDDCEADA
@>chr21:9686782-9686881-4
GCGGCGTACTGCTCGAGTNTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCAGAAC
+
ABC,?G?FF?GF@/AAFA#ACDI@B@EEFF@G@DDAECBIAAH1?C?CHIGDBAGBGFHIEE?BAFDCI?BHH?AI?DDIDDEFBBHE@ECEI@IACCIA
@>chr21:9686782-9686881-5
GCGGCGTACTGCTGGAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAAGATCTGAATGTTTGACCNTCAGATGGGATTCCAGAAC
+
GG@H?FBIDCG@FAA?ICFABGC@A?ACIDGABFFBEHFADDGEG@BC?G@@CBCC@DIAFG1HE@AIC?FBADGG@DG@!H??5?FFADFBEFGIGDFG
@>chr21:9686782-9686881-0
TCAGACGGTAATCAGCAGTGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCA
+
IBDFIBB?DAG@IFHHCF?GHBIHG?BGFIEHIA?EHHIHDIDIIFIH@DHCHBB@FD@/FFGACGBHE?DAFCBFDBGIB?IIG@D?@FG@HFIECBDE
@>chr21:9686782-9686881-1
TCAGACGGTAATCAGCAGTGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTCTGTGAGTGACAACCATTCA
+
@I@GFDABE?ACEEHDCCGA@ABIGAD@EA@BFHGFD??BIIBHCDEEADDAD?H@?ECBDFGFEBIFFEIGGDFCIGIH%F@EBCHEI?DI?@DII@@C
@>chr21:9686782-9686881-2
TCAGACGGTAATCAGCAGTGTTCTGGAATCCCATGTGAGGGTCAAACATTCAGATCCTCACAGCAGTGTTCTGGAATTCTATGTGAGTGACAACCATTCA
+
@FD@CDFCICHBCHC?ACA?HG?@??IFFHEBBICBH@?DFADBC@AECEEDC@@EG@HICG@@EBBGFDHAGF?DBFD@IDHHBE?FICDGDFFF?HG?
@>chr21:9686782-9686881-3
TCAGACGGTAATCTGCTGGAGTCTGAATGGTTGTCACTCACATAGAAGTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCA
+
BHA@D@E,A@@DEB?CEG?HIBGFECBAEGCCDBEHDHDFCCCDCGE4EAEGBAIAIF@FG@@EFDFEBHBC@BCIBCI?FF@FH@HD??EDEDGIHEIE
@>chr21:9686782-9686881-4
TCAGACGGTAATCTGCTGGAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCA
+
DCDCF?GEGDDFAEAFFIHHAGHHEH?IBBIHHC?CAGBGGCD?FD@CBECHA@DAGBDFIA@FIBHG??CCHIGIIFE?CDBAEH@HGADC@CBHAGGD
@>chr21:9686782-9686881-5
TCAGACGGTAATCTGCTGGAGTCTGAATGGTTGTCACTCACATAGAATTCCAGAACACTGCTGTGAGGATCTGAATGTTTGACCCTCACATGGGATTCCA
+
BGHH?EFABFDFBB@?HGDHGGEGHH@?GC@BFGIHIECHEAIHABHCFBEC?CDHD?IBAFDEIA?DCAHGD?DEFAAI?EAGBGHAGHGC?EEIDFH@
@>chr21:9686878-9687025-0
ACCACTATGTCAGCAGTGTTCGCTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTCTGAAATCATATGTTAAGGGCAAACAAACAGA
+
IH?ABBDEGFE@I?H@AEGIE0;I@GE?HFED@HHE@I?BGFH?G?A?GBD@FFDFHADH??GCIF?D=FGIA@CEB?GEAIHFFC@HE@@CE?4EGBE@
@>chr21:9686878-9687025-1
ACCACTATGTCAGCAGTGTTCTGTATTCCTATGTGAAGAACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACAGA
+
BGHBIFBE?EDB@?BGEFBFHGBED?CEIG@EF@FIDA+AI@FEEICDF?IDBEF?H?BFI@I@AIG?CBI@E@CGCEGF?AHADCCGBGHEGE/D?@EF
@>chr21:9686878-9687025-2
ACCACTATGTCAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCAAATGTTAAGGGCAAACATACAGA
+
EHGIHCE?AD@@CBH@HHBDFIFDBGIHBGDGFHGHEDBD?CC@GDH?EB?EIHCBGH?CFG?IFBFB?HEAH@AE?2IHGGFEEAFHHAC?GHEEIB??
@>chr21:9686878-9687025-3
ACCACTATGTCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCAAA
+
HGCGCGICEAHHEEGHA@??CIFGGGG?HIF?BBDIFEDCFDA?DDBBHGIF@G?IEEAA?BDCAHGAFC@BIA@G?CA@@F@D??EBHI?@BD?DIDEA
@>chr21:9686878-9687025-4
ACTACTATCTCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTATCATATGATTTCAAA
+
DB&EECHH$A?E?GBFFAICEDCHICEDAHIC?D@F?DDEHH?@AICG@IHG@DGD?ICAD@BBEGHIEHDGHEBGFE@ADICGD3?BGGDC@D??A??G
@>chr21:9686878-9687025-5
ACCACTATGTCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCAAA
+
@HEHHAAD@FEEFAE@DDEBAHFGBAIGACGD?BCFAGHIEA?EEIC@HCGAAEDHB@??@?FE@CACIBIGFGEEBHACCD@CD???ACFAB?CAGI@C
@>chr21:9686878-9687025-0
CTCATACCACGCAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACAG
+
BCFIBIHADEIAIFG@BA?DFGBE?HF@GACED@F?BFIDBII@GC@FHI?DDI@HDFCFDI?CC?CGGDB@HFEH?AIEFGH@GBGAHFGBAHEG@IDF
@>chr21:9686878-9687025-1
CTCATACCACGCAGCAGAGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATNCAG
+
C?EFI@DG@HH@@BDG?*AGFCF@?IIIEH@@GIGBHC?HC@@HE?IHIHAFFEFDFBG?A?CAH?AGHAD?@GHEHDDFEHBEHGD?BDBCDEDD&DG?
@>chr21:9686878-9687025-2
CTCATACCACGCAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAACCATACAG
+
EBHFEGFCF@?IDAGHDI?EDBD@DFAD*DIFFABEDECHAFI@G@BHCACIH@?AI@AEHHEFABA@GEIGBBADC?DDA@AB@@AE?E@D3/AEA?HD
@>chr21:9686878-9687025-3
CTCATACCACGCTGCGAAGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTGATGCTAGGGTCTGTATATTTGCCCTTAACATATGATTTCAA
+
AE@CAHCGGF@IICDBA#E?D?EDCFFHEGIGBIACFHDB?FGG?DFBE?C?GHAHEFGEAHCIGH@HCDBHGI@;IGD@HBE?FBFB?I?GFF?EGAAB
@>chr21:9686878-9687025-4
CTCATACCACGCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTGATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCAA
+
GCHGHC+FEB@ABGI@G?HDHIFCF@@?A?CF@GG?CAIABA?FI@DFDCBA@@CFIAD?EBFBECFA?@GD?IDCBDEIABGHGAABAHGCAEAAHIGI
@>chr21:9686878-9687025-5
CTCATACCACGCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTGATGCTAGGGTCTGTATGTTTGCACTTAACATATGCTTTCAA
+
DI?@DIHDCEBCCIFGIFBEB@DDA@@IBBG@AHC?FHD@EBDBGIBHC@BHIHHIEEFDEBA@FFCBGHHH@EDBGHEAC2DFDBEDCG?GC*FIE?HC
@>chr21:9686878-9687025-0
GAAGGTCCTCAGCAGTGTTCTGTATTCCTATGTNAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACAGAC
+
@DBHC?@?@I?@BAFII?@7BEHEF?CFEHFEE4IGEDIB@DIF@BFCCG?AI?HED@GDB@EDEGHGB?E?ADHDIFCC@@FCIEAE?GCB@EEFHHAD
@>chr21:9686878-9687025-1
GAAGGTCCTCAGCAGTGTTCTGTATTCCTTTGTGAAGGACAAACATTCAGAATCCAGGAGGAGTGTTTTGAAATCATATGTTAAGGGCAAACATACAGAC
+
?FDGAIHDHCACHEDFHEI@BA?CGGFCC5BF???GFF?FIECED@CHCIF@ACCAFACF(BFDFD?CBHI?D@FF@C@ACI??B??AAHAGI?GIAHEH
@>chr21:9686878-9687025-2
GAAGGTCCTCAGCAGTGTTCTGTATTCCTCTGTGAAGGACAAACATGCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACAGAC
+
?@F@CHD@FABGI@I?DAGC?EG??EBHB#GHCF@D?DA??FCBGD0FBF@EDC?HFHIFFADH@CF@ICCCID@?@HGDA??FIGEHIBCHF@@HICHF
@>chr21:9686878-9687025-3
GAAGGTCCTCTGCGAGGGTCTGAATGTCTGTCCCTCAGATATGATTCTAGAACATTACTGCTAGGGTCTGTATGTTTGCGCTTAACATATGANTTCAAAA
+
@GBDCDD@ED@HAHDEIFGEFF@EDEHBAC@AHDB?H"GC?HIA@A?BFIEIDBE?A=AFGHAC@?B@BG@AIH?BHD@+ACCGAGBDEEG@;G@FF@DG
@>chr21:9686878-9687025-4
GAAGGTCCTCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCAAAA
+
IBIDE?CIBE-HIC?C@@CHE@ECICIIHF@H?DIFGAAECC?@FH@?A@FCEDHDH?IBBIDH?FBF@BGB?FED@FEBAI@?@D?IBBIAE@CEEFG?
@>chr21:9686878-9687025-5
GAAGGTCCTCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGCTTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCAAAA
+
?EAFF@CHGEBHGA??DAACB?E@CDAC@ICHB>?HDBGIBIH8CHECFDD?ECBEADCFDHAHDGCA?HHFBAIIFBD?BIDAA@EA@D@IGD?GCFC?
@>chr21:9686878-9687025-0
GCGGCGTACAGCAGTGTTCTGTATTCCTATGTGAAGGANAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAGCATACAGACC
+
EBHG??HFCC?HG@?FCEBBFBHC@I@BGIDE?CGBD@<DG?HEBAHFEGB@CAE?FEAADDECDGIB@@GHCG?GG?@GAIDID?C?@.BFIBGIFD?D
@>chr21:9686878-9687025-1
GCGGCGTACAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACAGACC
+
@@@BFH@@?EB@FIE)DFBIG@@EGIGB?DB?GHEI@BIABI@GHE?BHDBDEFB?BE@?HDIE@ABA?GIBFCFECBG?BGCAGBFFBI@@?D@ACBE?
@>chr21:9686878-9687025-2
GCGGCGTACAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAANCATATGTTAAGGGCAAACATACAGACC
+
@EDFDDI?@?I?D?B?ICBBH?EG@F?DHBFAGEFIBCEIBBCHEEDI@GBD?GHBCEDCGDBDCBAG@FBC&@?@FFHEGCF@CG@C?DHADI@HDIAI
@>chr21:9686878-9687025-3
GCGGCGTACTGCGAGGGTCTGAATGTCTGTCCCTCGCATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCAAAAC
+
HBEDGFFHBICDB@BGG?BEGCC?GEEFCCHCHBC+EF?ABHGBHAAC?BI@IEAG?DBHC@?FACCHBGGDICGC2IBFG@G@@H?FGEDA?ABAEIC@
@>chr21:9686878-9687025-4
GCGGCGTACTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCAAAAC
+
BCAE@IIDFACEG?DI@BAHFAH@@EBDGEDAHBI?A@GCIBD@FGI@I?EDAA@@BFF?B?CD@BAG@CG@HECBAIC?GG@A@GCFDFFD@BCC@DDI
@>chr21:9686878-9687025-5
GCGGCGTACTGCGAGGGTCTGAATGTCTGTCCCTCACATATCATTCTAGAACATTAATGCGAGGATCTGAATGTTTGCCCTTAACATATGATTTCAAAAC
+
CCAI?CGBEHBBC?IGI??@CA?DA@ABAFF@?IDFDB@CG.A@DDF?@?IHBIDAADED4IBH/EFGC>H@H?CHHDAAE?ABCI@D?F@IAHG?G?DC
@>chr21:9686878-9687025-0
TCAGACGGTAATCAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACA
+
GBBIC*H??@EBABHEAIEGAFEFBFAEAB@EIGF@ACCF?ECEDIIGC@GAEC??H?AB@?AD@GCEHBCBBH?EAGDGB@DGFBEADFG@CECGGI@?
@>chr21:9686878-9687025-1
TCAGACGGTAATCAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACA
+
F?F?@AICDA?D?DECA@HII@BCCGF?FEGIB?EHCHH?E@DBBBB?HAGHFFFDFFIHIBBDBEIEFC@ID?FB@BGIAFIBDDCB@GIDCH@BCBHH
@>chr21:9686878-9687025-2
TCAGACGGTAATCAGCAGTGTTCTGTATTCCTATGTGAAGGACAAACATTCAGAATCCAGGAGCAGTGTTTTGAAATCATATGTTAAGGGCAAACATACA
+
EFD?DIA?GDD?/@@F@EIBHCEGFIAAHEBI@CIHHGGGIBH?F@DHIFBECBGBAHIEDIACA@ADDADF?FIECI@IAEBGGBEIFBCEBHBCECDG
@>chr21:9686878-9687025-3
TCAGACGGTAATCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTGATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCA
+
AAE??CFDBFGHDHEE?DIDFEEA?E?@EECCAH?ADAHIA?DH?HCFHGFECBBBFDAEC@AEDCG?IGBHCIEECBGAAD?@HCFGDDDAGCFHEFBE
@>chr21:9686878-9687025-4
TCAGACGGTAATCTGCGAGGGTCTGAATGTCTGTCCCTGACATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCA
+
@?IC?CIDC?DC@@??D@FAE@CEH@@DAGCDCEFC@A8EHH@D@C?A?F?HA@ICDBHGE@IBDCAEFCDFAFEABAH@IE@@HFGFGDDBCFCD?C@A
@>chr21:9686878-9687025-5
TCAGACGGTAATCTGCGAGGGTCTGAATGTCTGTCCCTCACATATGATTCTAGAACATTAATGCTAGGGTCTGTATGTTTGCCCTTAACATATGATTTCA
+
@@GCAFIEFCHGD@ABF@FEH@IHGEA?C?IEIAIC?EFEBAAGGIECGFIE?CGAD@BH?@BHD?DIAHBDIFA?ICGAB?BGHDHDID??I?CF@E@?
@>chr21:9687978-9688049-0
ACCACTATGTCTGCAAAAGTCACCACTGACCAAGTAGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGTCTGAGANCGGAAGAGCGAAAAA
+
EICB@IG?@@AIEFBA?BE@B@GDCBIHICHEBBFABFDA?@AIC?CEGFAEI@FF?HBBG?EIAIFBH@@C@II@H7HDIC@C"IIDAHCGI@DFGC?@
@>chr21:9687978-9688049-1
ACCACTATGTCTGCAAAAGTCACCACTGACCAAGTAGTCTCTGACCAGGACGCTACAGATCAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGACAAA
+
BE?FCCECGE?EACC@FGF?CGDHD@HICIEEED@DCBHCFIG0?ACHC?EHDIFADGIF*IA??HCCICBECFI@IGDAG@B@@IA??BCAAEIG"@AB
@>chr21:9687978-9688049-2
ACCACTATGTCTGCAAAAGTCACCACTGACNAAGTAGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAAAA
+
G@@AGGAFHHEGCABBG?AGFDBDIFEBEB2GBDAE@@E?EGA@?FFFG@FHCGBGDE@AE@H,EI@IA@BFCECEECICIGID?FA@GHBDBI??C?IC
@>chr21:9687978-9688049-3
ACCACTATGTCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACTACTTGGTCAGTGGTGACTTTTGCAGAGATCGGCAGAGCGAAAAA
+
BECBAADHHH@CDCE@A?,@@AEIAFCH?FGFE@FGCI@FAIGB@EHAC?IFACC@IBFG@HAFA?EGADIBHHFED@FAFCB#H@H?%DFGA@@@?GHI
@>chr21:9687978-9688049-4
ACCACTATGTCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGATTACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAAA
+
HDBCG@;BCBE?HFCAGA@AHI@EG@BABCIG@HAHHCFBGC?AAEFAD@EGBI*@?AABF?FGCGDG?C@?@CAEG?GGAH?CB@HD??IBFB?HIGH@
@>chr21:9687978-9688049-5
ACCTCTATGTCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACTACTTGGTCTGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAAA
+
DHD"IAEDCCEFC@GAB@CIABBD?HDADFC@FDFC?BCA@HHFFBFDBHDIAHBG@FCABEED.EECECIEBICI@BDAAFHDAIECIDCE?HCIIIHE
@>chr21:9687978-9688049-0
CTCATACCACGGTGCAAAAGTCACCACTGACCAAGTAGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCCGACAAGGCTGAGATCGGAANNGNGAAAA
+
FF??IIHIHHA#CG@@BGDGEGCBH?FIHEA?HDH?HDCHHDFECDG@IA?HHAGHAHDAC@G?IE@GEFG%DA@HFCCFCECDHHAAAIE')@3@I?H?
@>chr21:9687978-9688049-1
CTCATTCCACGCTGCAAAAGTGACCACTGACCAAGTAGTCTCTGACCCGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAAA
+
B?BEA)??H@BH@@@GHHDE@'F?EHDDI@F@HGAAAEACEGGBEC?>BDAEHECCAHF?CCIFIDHGDHEFIDFHGBDGGDFHF@DFEBDAAAIH?ICI
@>chr21:9687978-9688049-2
CTCATACCACGCTGCAAAAGTCACCACTGACCAAGTAGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAAA
+
DAII9B@HGDDC?IH?ABFH@GBBD@I@?G?EI?FHE?@H?IEBICI?EH?EHEC@C?GBBDBHECCGFF@A@GDCFBDGEI@?@@HBCB@HE@AHDICG
@>chr21:9687978-9688049-3
CTCATACCACGCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACTACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAA
+
ICFHBIEFCI@DGGGFGBBDDIAFE*FD?AIIADGE?IHEECHGCECC@IGHHDFIA@GICB?HEE@DBGCE?AFEFF?ABH?AA@AGBDHFD?@>GBBA
@>chr21:9687978-9688049-4
CTCATACCACGCAGCCTTGTCAGAAGGACCTCATCTGTAGCGTCCTGGTCAGAGACTACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAGAA
+
EH?EGEEEEGACGCEHGGAGF?B95EAEHEC)HIG@CDHCEFGI@G@GG@ABIFGE@FIEBCBGGCCAH@HCEBDAEDBBIEHEHCF@AE?F@?EFA"@I
@>chr21:9687978-9688049-5
CTCATACCACGCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACTACTTGGNCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAA
+
GFHDHIHCDA@IGDIAIEICCAHACBFHFGD?BF?HGB??C?F@HADBADFCAHBHEA@HIAH(CB@AI?GGFBFGC@CCAHEHBD?CG@FEHFH?FE@I
@>chr21:9687978-9688049-0
GAAGGTCCTCTGCAAANGTCACCACTGACCAAGTAGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAAAAA
+
D?GI@BI?@G@CDHEH6FD@?B@DD?@AAEIEGEBB?FF?HHH?EA@GEI?EHFIHE@AF@FEE?@HB@HEB??EE@HFB?B?DEI@BDGICCAAIHIF@
@>chr21:9687978-9688049-1
GAAGGTCCTCTGCAAAAGTCACCACTGACCAAGTAGTCTCTGACCAGGACGCTACAGATCAAGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAAAAA
+
ICD?DIGD?IGB?@CI6A@?GDCBEBEEHHH?C?CD?IDB?HAAAEABEIFCFDIHADG*@6FAGFI?@B?BH?AEGHA@IIE@GABEADIDD@DEBAH?
@>chr21:9687978-9688049-2
GAAGGTCCTCTGCAAAAGTCACCACTGACCAAGTAGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCCAAAAAA
+
CCAEIFGHDEBEEAECABICCDFAIBBCGB@A@CHHGHFCCGAH@CB@F@ADCAGCE?@ICHDBI?H@CBDG@ACCII?FDIAIGEDIFGCHD'GEB@IH
@>chr21:9687978-9688049-3
GAAGGTCCTCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACTACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAAAA
+
DGDHD@E@DAACHA?GBAAH?IBCHBCGHED@GAB?DAEDFEDFD?EBFGH4@FHDCAEHFCIIA@H@EB?DIBFA@FBFIAIEE?HCFECA?HFGICBH
@>chr21:9687978-9688049-4
GAAGGTCCTCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACTACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAAAA
+
C?CGIHFDAEGIEBFCHGCIFBAH@F@BI@HI??DAC@AG@EFGFFI@AI@IBDEIAC@EAI?F@ED@DHA@A@CAHD@IDI@AFAE?GHDECFC?BGGD
@>chr21:9687978-9688049-5
GAAGGTCCTCAGCCTTGTCAGCGGGACCTAGTCTGTAGCGTCCTGGTCAGAGACTACTTGGTCAGTGGTGACTTTTGCAGAGATNGGAAGAGCGAAAAAA
+
FIDEADFBFHG@FHGH@GAFHIAFCDHG@B%@AGAEGEIGFCFIDFFCA?@HCIBFDIABDBGDI?DDBEHGEFH@HBICBGAD#HDFDBHCDGICEDD@
@>chr21:9687978-9688049-0
GCGGCGTACTGCAAAAGTCACCACTGACCAAGTCGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAAAAAA
+
EFIEBD@FIFIDDCFICDCI@EEFIFCBB@HADGI@IIAD?H?DCGBIDCEFHGIDCAGDHIAEA@E@D@E?FI@ID@@EEEAEGE?C??@CBHIHDDIA
@>chr21:9687978-9688049-1
GCGGCGTACTGCAAAAGTCACCACTGACCAAGTCGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTAAGATCGGAAGACCGAAAAAAA
+
CAFE?AADEGEDAFDE@A@AIIBBA?GCGACB@ABII?C&BGDGDIHFBDEF@BEGCGGHGFIDIDF@@EIB?AF@C@4GHBHDHAG@E@;I?DHGCGEF
@>chr21:9687978-9688049-2
GCGGCGTACTGCAAAAGTCACCACTGACCAAGTCGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAAAAAA
+
@G?IBFG@BFBCD@?A@GBDHAAGGAI@GCDCBGBI@EBHCABFC@<ADIBHFFCAD?EECEIC?FIIFAED@ACGEGGCFGE?F?IC?FG@EAA?GHDH
@>chr21:9687978-9688049-3
GCGGCGTACAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACGACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAAAAA
+
HABAABA@BBDGFA?I???F@CCB?FFFDFGC@D?EIEIA?CAE?G?DBIICABAG?HFH@DBHDGEAFDE@EBBGEBDIDDA?@GCFDDAF@BHEBBCI
@>chr21:9687978-9688049-4
GCGGCGTACAGCCATGTCGGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACGACTTGGTCAGTGGTGACTTTTGCAGAGATCGANAGAGCGAAAAAAA
+
ICF@?D@AFB?CI#ABI@-AFGF@EBAEGC@IIDD?IGDDGEHD??DCA@HDCEAGGFCCBA?@@CBA@C>B?D?DCHDAGBAGD$8CADCCHH@C@BEE
@>chr21:9687978-9688049-5
GCGGCGTACAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGACAGAGACGACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAAAAAA
+
BIFIBGHIE@IFFAGAEFCCHBEE?BG?DFCCHDABG?ICBG@EB<??AED9FCB?@ABGHHBEEHG?GD??G@EFBAGHIDGEDCHC?BFABIGHCGBB
@>chr21:9687978-9688049-0
TCAGACGGTAATCTGCAAAAGTCACCACTGACCCAGTCGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAA
+
IIB@HDBD@?DI?EGFG?C?AFGD?@GD@FAFG0ABIBGID@F@FCAG?BA@@H?GEA?GGDFFEGBDD?BEIFICDHD?@GDIIBA?DDB@IAIHAFBD
@>chr21:9687978-9688049-1
TCAGACGGTAATCTGCAAAAGTCACCACTGACCAAGTCGTCTCTGACCAGGAAGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAA
+
@ABIB?FAEHGC?III?G?F?GA@G?DCGDCICGF?GC@HBIH?HGA@EFA@>HDE?A@GFFCHDGECHFC?B@@CC?EB?FIC@FFH?BFCFCEGIGHI
@>chr21:9687978-9688049-2
TCAGACGGTAATCTGCAAAAGTCACCACTGACCAAGTCGTCTCTGACCAGGACGCTACAGATTAGGTCCCGCTGACAAGGCTGAGATCGGAAGAGCGAAA
+
IEABAFCAIDBFGCCHAI@EIFCEFI@ID@E?@?C?DGDIH?GECEBCAB@GGEAGBA@FI?FBCFFIIIDGDDCHAADGIAEBIE?HII?EEGHI@GAI
@>chr21:9687978-9688049-3
TCAGACGGTAATCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGACACGACTTGGTCAGTGGAGACTTTTGCAGAGATCGGAAGAGNGAAA
+
?CGAE?EEFHAB@BGIFDDBBHCGDH????BDCCFDEGAH?IAFBFB@FGHBAA#DDADIBHG@ID@?GGI<DFGH?HF@EHIGCGHAC?HEBBA!CEIG
@>chr21:9687978-9688049-4
TCAGACGGTAATCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACGACTTGGTCAGTGGTGACTTTTGCAGAGATCGGAAGAGCGAAA
+
FCAIEHHFBGFHFHCBFG@DHC?FIIIEBDFAHAGFGH?CAIFA?BDCDFEI?A@DFAA@IAIHGAFDFBCFIDIBBAECHCBIIBGICH?CCBEFBIID
@>chr21:9687978-9688049-5
TCAGACGGTAATCAGCCTTGTCAGCGGGACCTAATCTGTAGCGTCCTGGTCAGAGACGACTTGGTCAGTGGTCACTTTTGCAGAGATCGGAAGAGCGAAA
+
@?IAIIIFDIDACFH@EEBCFEGGAHGD@BABAICC.EBEGCFIBD?A??IECHIGBCCBD@EIB@CEG@?G2CIIGFGFEGCH?A@I@CBIIGGED@HB
@>chr21:9690886-9691006-0
ACCACTANGTCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAGCC
+
CEAIC?D,@@HFGGCEHHBI?EEFIGCCGF@?D?CDBBEBH@GF@DIFB@IA?HE?BCFG?GDEHIABB@GIGBBFGGCG?GEA@AEDIBCGI@F@EGAI
@>chr21:9690886-9691006-1
ACCACTATGTCTGCTTTCTGTATTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCNACCAAGAAGCCCGCAGTGCCATATGAGCC
+
ADIEHHBBI@??CGF?CH@A2F9?BFDGDIAECFEGFIEFGDBIB@CBB?BIBII@CCEGEBCA?G?HBB>@CCAFD?EIHHCHAIE?I@F?EGF?EECH
@>chr21:9690886-9691006-2
ACCACTANGTCTGCTTTCTGCACTTCAAAATAAAGACCNACTGAAGATGGCCNGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCANTGCCATATGAGCC
+
AAFFAGC>A@ECHFAADECH?AF@BBBH8GDE@C@I?F+EDHEBFFB@EBDE9CG@GEBD?BI?CDFBHFGGD@AF@B@@@GFHBC=DGHDGCDI?FCCG
@>chr21:9690886-9691006-3
ACCACTATGTCTGCCTTGGGGGCTCCTGTCCATGCCTCAGGGCTCATATGGNACTGNGAGCTTCTTGGTTGCAAAGNGGCAGACCACAGGCCATCTTCAG
+
HBD@HBBI?HHAHGGFAFE?F?AE@@'BCFBFCIIAIC@FIC@DF@B?DHI"DEDD.E+IHHCD???CADACHGF@.AAD?@IEI?GFIHEHBEHEGEEF
@>chr21:9690886-9691006-4
ACCACTATGTCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGNCATCTTCAG
+
FAFCIDFAAI@HF?IFBEEDDIDBIHADHIAF?BF?FEBGDGG@IAEAHIC?ICHDIGH@BEFB@FIFCI@?I@ID?EEADCCG@AEG?C7DECACF?BG
@>chr21:9690886-9691006-5
ACCACTATGTCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAG
+
AFCA?AIBB@AFBAHAGDBBAEFFFFGC@BGBCDGHDI@BHAI?AFBAEBE@@GIFCGIIFEFCDEABED?ID@H?HFIHCAEA@BE?GH@G@EBBHHFD
@>chr21:9690886-9691006-0
CTCATACCACGCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAGC
+
GAIC??BGD?ICBCHBBE?I?A??CI?CDEACDI?DCFDHDGAHB?B?CCAH@F?HHG?CCG@DCCBC?ACFCGFBDEGHACDAC@DBF?IHF@B?B@HI
@>chr21:9690886-9691006-1
CTCATACCACGCTGCTTTCTGCACTTCAACGTAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACNAAGAAGCCCGCAGTGCCATATGAGC
+
HIGFABHFB?HIBDAFH@EIE@IADIEFC?'G?CC?I@CHCGEEGGBIG?EA@EBEGE@@DDDGEAGBFA@EFB*A@C@CIIBGFC??AG?BIHIIEG@F
@>chr21:9690886-9691006-2
CTCATACCACGCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAGC
+
GE?HHDGC?CFHC?IC@DGFDIH@DGC?GCAIGHD@CBH@IGAH?IC@BAE@CDACFCEADBGBC@?BIACDGCB??GE?CA@?BFACHC?ICDICC?G?
@>chr21:9690886-9691006-3
CTCATACCATGCTGCTTTGGGGGCTCGAGTCCATGCATCAGGGCTCATATGGCACTGCGGGGTTCTAGGTTGCAAAGNGGCAGACCACAGGCCATCTTCA
+
@FECFED?H>ECCEB-GEHFIEBDFA"?ICDHCFBHHG@IBHBFCFHGDI?C?AEBEFHA?8@?GD.GD?CG?GEGE/A?ECBAD?CADCHFBGGIC?BA
@>chr21:9690886-9691006-4
CTCATACCACGCTGCCTTGGGGGCTCCAGTCCATGCATCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCA
+
@IH?GACHCCAIG@@?CIDCAI@@ICGGADDIH?GDGB?EGIIHBFHA=@F?EHHIFCHEDHHIAA@GGAEIBC??C?ECHD?EG2EHI@GFIHEIFFBB
@>chr21:9690886-9691006-5
CTCATACCACGCTGCCTTGGGGGCTCCAGTCCATGCATCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCA
+
ECEAC?CBFGIE@ECHG?ADF??AIH@F?BCFD@HGFHAFDE?FHBAIHCEGC?AH@H?@ICCFBG@?IADF@C@@@@AEHIFC?HDBHICHCFHE@BCA
@>chr21:9690886-9691006-0
GAAGGTCCTCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGNCATATGAGCCC
+
A?I?FGIBGG?HGFH@?GACCBCCDAEDD?AEIFAICCCDGGDFDBCD@@BI6IIFIBEIIBCGDDB?BIHHFECCAEBC@?CFACH@"?A?DI?GD@A@
@>chr21:9690886-9691006-1
GAAGGTCCTCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGACTGCCTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAGCCC
+
D?HDEGGCFDEH??@BAAFEFFD?G?DAIGCBFA?@I?FFC?BBGICBFBFHIFDD%CABEH@F?BAFHGIH@@@BB?ABAEFIAFDIFFI?FFBG@AIC
@>chr21:9690886-9691006-2
GAAGGTCCTCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGACCGCAGTGCCATATGAGCCC
+
DAG,EAAAEBIDB?A@EE?EDAH;HAHIEII@AGFAABI?HCHFF??C?FHFBI@HAAB?GIIECGIIH@FH?@B?B?@'HBH@?FDEHHBCGBADDDBE
@>chr21:9690886-9691006-3
GAAGGTCCTCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAGT
+
HGIDBC@HIB??BEBBAIH@@BHHGB@EGB@CGHEDDEGIDDF?CICEABIIB@EBICCCDAADAEBEAF?DB@IBAGHCGDBGCE@?IDDGA@ICCABF
@>chr21:9690886-9691006-4
GAAGGTCCTCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATTTTCAGT
+
BGBGI@CHHA@@HEABDCGBB@CD?CBDGGA?CDICBFBF@B?BF,@AIECA?FDGGH@IHIHF@?GADHEH?A<HGCHECEII?ADB@IHD@;?@@IDA
@>chr21:9690886-9691006-5
GAAGGTCCTCTGCCTTGGGGGATCCAGTCCATGCCTCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAGT
+
F@DGEHBIEFB?IDHFG9E?B5EAF@IDI??GIHGID@DBCD?EG?FDHBFDBHH?B?IAHIHADAI?H@HBB??AIHHBE@AB?EBDAIDBGHDD@EED
@>chr21:9690886-9691006-0
GCGGCGTACTGCTTTCTGCACTTCAACATAAAGACCTACTGGAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAGCCCT
+
HD@CH@AG?FIFD@CBEG?AEFECDC?BBID?EDCCGIGDD,DDAFDECC@@FCDCDIIGHAD?BE@EHA?F?@B??DGAFAEEGE?DAEA@GFIEIE?A
@>chr21:9690886-9691006-1
GCGGCGTACTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCGTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAGCCCT
+
DB@@IHGBCEHEHBHCIDGGEEEEEHHIG/?HDBHCGD?BFICH@CHH@D?BE?BFCGAI1DD@C@CF?BHD@HCFEB@H@G@CEAHAIBGACHCEBBIH
@>chr21:9690886-9691006-2
GCGGCGTACTGCTTTCTGCACTTCTACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAGCCCT
+
BFFAHGID?@DCIFIAI@AHAHDH/AFE@G??CEBCB?/@BBFDAD?HFEDCDIH?FCCB?IECGGE?A?BGAAADHBD?FDBIC@FAF@AEHHAE@HC@
@>chr21:9690886-9691006-3
GCGGCGTACTGCCTTGGGGGCTCCAGTCCATGCATCAGGGCTCATATGGCACTGCGGGCTTCTGGGTTGCAAGGAGGCAGACCACACGCCATCTTCAGTA
+
I?H?GFAFAC@BHG*AHEB@?DFDCDE@GICEGAECG@I@HAI?DDFEIAIGABGHIAF@I@A*CHDD@E@F)DHAGE<DGHAI@?-@FC@FHGIGFEH?
@>chr21:9690886-9691006-4
GCGGCGTACTGCATTGGGGGCTCCAGTCNATGCATCAGGGCTCATATGGCACNGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAGTA
+
I?EEGBG??@DI;IBAGGCFEDGEBE?H5ICFCFHAF@FF@CEFDBBHCIFD1DCAG@IDIEIEHG@CAIEG@FH?AAD?HEEHHADBHBGFCC@D@BDB
@>chr21:9690886-9691006-5
GCGGCGTACTGCCTTGGGGGCTCCAGTCCATGCATCAGGGCTNATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAGTA
+
D@IG@BCFE?AG@@E?G?BIHAFDE?DGDGHBGIAE?HA@?H1A@GB@EIAEH@H?IECGEG@DAFGGGDCEBHI@?GD@AEI@DF@FEECDBIF?EIDE
@>chr21:9690886-9691006-0
TTAGACGGTAATCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGNGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGCCATATGAG
+
D<BG?AIADHCD@??B?C@AFAG@A@CBA@I@AABAI?FEG@@EEEDD?IEIHEHD)IBDBAEGDIIAFHBF?AACBA@IGH?BC?EB?CBGICICIGHG
@>chr21:9690886-9691006-1
TCAGACGGTAATCTGCTTACTGCACTTCAACATAAAGACCTACTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAAAAGCCCGCAGTGCCATATGAG
+
H?GIHF@HCGAEI?FC?H.?FC?HAB?BBFCGHEGG@GIGABFGCBCDDGBE?CIG?BAAE?AECGB?@H@F?CGFH?)FDF?GEDDGBIDCCHH?FGHF
@>chr21:9690886-9691006-2
TCAGACGGTAATCTGCTTTCTGCACTTCAACATAAAGACCTACTGAAGCTGGCCTGTGGTCTGCCTCTTTGCAGCCAAGAAGCCGGCAGTGCCATATGAG
+
F@AAAEFCEAIDICH?BAFHHD@B?ACICH?BGA?EDDCE?D@ADDI?)IGCDH%AAGFA?@DCB?DHBD@@A*IBICAHCFAC>FIBICCBGC@DGHAH
@>chr21:9690886-9691006-3
TCAGACGGTAATCTGCCTTGGGGGCTCCAGTCTATGCCTCCGGGCTCATATGGCACTTCGGGCTTCTTTGTTGCAAAGAGGCAGACCACAGGTCATCTTC
+
EBFDDCB@EG?E@FDH@CF?CAC(HEFCFAI@8?EEDD@D1AG>?EGC?HFCGAA??8EDDIHEFDIF-@G??DGDE@CEIBE??FEAA?EG$AIBFDDB
@>chr21:9690886-9691006-4
TCAGACGGTAATCTGCCTTCGGGGCTCCAGTCCATGCATCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTC
+
BE@IHDEHIC@IFDEDEGH/FGGIGADHIID@BBGABC@FEHBCGFE?AD??FA?EHCEIAECIBCIDGHBB@??D?@FIFEIGE@BEEBHI?HIIECEI
@>chr21:9690886-9691006-5
TCAGAAGGTAATCTGCCTTGGGGGCTCCAGTCCATGCATCAGGGCTCATATGGCACTGCGGGCTTCTTGGTTGCAATGAGGCAGACCACAGGCCATCTTC
+
CI?AE.GIGH?AFFAAAH@CA@EDD?GDEI?B?IF?CGCGGE@?H?BIBEH?B@HIFCH??BFEII??@@HB@?FA(CD@+HAI@FEFG?@DF@B@GFHD
@>chr21:9691029-9691181-0
ACCACTATTTCTGCTCATTTTCTCTGTGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAAAAGCA
+
FIDEEEAE4AH?IG@DHB@AB!BGI@?IF@CAHFG@C@DHBH@GIHCC?E@@@IC@C@CCDIGEHDIHIIAA?AFGFCCHABC?@?DGED?AFFFCIGC?
@>chr21:9691029-9691181-1
ANCACTATGTCTGCTCATTTTCNCTGAGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAAAACCA
+
E/FBFBF?E@ACEDH@IIFH@I(?BF2@BGA@IBGAAEEAIEBBIE@CGAGBADGGHHEABCECGGCFGIEEAD?GABACC@IDH@GFDBECDCH@C2I@
@>chr21:9691029-9691181-2
ACCACTATGTCTGCTCATTTTCTCTGTGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAAAAGCA
+
A?CFEIAI?HGCGC?FIFBID@@?FBFGHIDFHA?CDEACBD@C@GIBDEGBB@DHIGC?B?HCBI@@EGA@HFE??@AICEDI@BIEGI??BGI@D?@B
@>chr21:9691029-9691181-3
ACCACTATGTCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCATTGCAGAGGTGGCCGGTTGCTTTTTGAGCCAGCCTGGCCTTCCTC
+
HDDI?@GEBIEDEEEI4@CDEEEFHI?DA?FFF@@?DG???B@BCCGBABC@I?+AAHGAG@AEDEFHBGFB?HCFEB@BEAFBGFB@H@FFHI?BD?A@
@>chr21:9691029-9691181-4
ACCACTATGTCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTTTTTGAGCCAGCCTGGCCTTCCTC
+
AIG?G@GI@@?CB?EABHBH?FDI?IFAGG@DGIGF@FAD@?D?H@EEFEFEGHIIC?EGAC?GEBD@HGFFAFAFFIG?GDFDFBHBCDDAIHHI@ACE
@>chr21:9691029-9691181-5
ACCACTATGTCANCAAGTCAGGTTGGTGGCTGNTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCNGGTTGCTTTTTGAGCCAGCCTNGCCTTCCTC
+
BEDHA@BGI$AH0?EAHEGHIDF?IED?H@@G7FD?I@CIAAHEHIAAID@AHEFBH??CC?GCHBHH+??EGC??F?A@FGG?H@GAGG#I@@ECC?F@
@>chr21:9691029-9691181-0
CTCATACCACGCTGCTCATTTTCTCTGTGTGGCTCNATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAATAGC
+
CGH@GCI&DE@EECBC@EFECIAFED@B?GDEHC?$CDAFCHAI?HHCDDDF@GFEBHDCHCAACIAIBCCF?AEICHC?HG?@CD@HGFFAIBAA?IHI
@>chr21:9691029-9691181-1
CTCATACCACGCTGCTCATTTTCTCTGTGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAAAAGC
+
HFCBA@I@EFBFC@ADAB?H@?HIF@HDAHHEFIGEG?FCEBHAEHHCDH@AGCIE@GDD?BFEHGEAFDIACFIFHEGCFHCDFCGFC?@EEEHB@@AB
@>chr21:9691029-9691181-2
CTCATACCACGCAGCTCATTTTCTCTGTGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTCCTGGATACTGAGGAAGGCCAGGCTGGCTCAAAAAGC
+
BEIIFFGGC?@B;DEAHAHDIAFAGE@BCEGBEDFIGACHGGACEFHGHC@BHAICAAGGIBB$EDH(CIHACBG@IFDEBAIECIIDHEICIB>DGF@D
@>chr21:9691029-9691181-3
CTCATACCACGCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTTTTTGAGCCAGCCTGGCCTTCCT
+
B?BA?CA?DDHE@FGIGAIEHHEDGGBAII@ADFGAEFB?@BDCGFB?FFHAAGEI@I@BFED?EHIB@FGAFIHF@DGBCGAIDGB?BBCCA?H?ACAA
@>chr21:9691029-9691181-4
CTCATACCACGCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTATTTGAGCCAGCCTGACCTTCCT
+
?CC?GBGD@AH??EDDCBEFGFCCBCEIGDED?DA?B@GGC??IABGDACIIEIAGEHBHAIC@?EEHCCFE@GHBDAHGAHBCDCGF?EHI5FHBIHHB
@>chr21:9691029-9691181-5
CTCATACCACGCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTATTTGAACCAGCCTGGCCTTCCT
+
GHDG?@EAEBFIFCEEFHEGFGIAEC?F?EHFIBHBHAIHABE@IEEIBG?AGBBEBGBFEAB@E?GHFBCIEE@FBAHHFDH/CHDF?@FHDAAFFF?D
@>chr21:9691029-9691181-0
GAAGGTCCTCTGCTCATTTTCTCCGTGTGGATCCATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAACTAGCAA
+
?DC@IAIIBGHACIDC?CFHC@C=IEBHC?%BIEBAGGHFCIDH?EEICDIID?FICD?ICA?HD?@H@HGFHIG?ECDIIA?BIH@HEG@DI7@EEG??
@>chr21:9691029-9691181-1
GAAGGTCCTCTGCTCATTTTCTCTGTGTGGCTCCATTGGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAAAAGCAA
+
FDFBGEC@HBD?EBBFBCBEFGD@FGIAFGGHCB@IA!@A@GG??AI?AAEAAGCH?DGH@EC?FEG?BIBHGHG?BE??AE@CDBE?GABGDA?IGB@G
@>chr21:9691029-9691181-2
GAAGGTCCTCTGCTCATTTTCTCTGTGTGGCTCCATTTGCGTCACAGTTGTTGCATTGACTACTGCATACTGAGTAAGGCCAGGCTGGCTCAAAAAGCAA
+
D?@CHAGBE?HAEACDBDEHF?GBICI??BHG?ICBFB@#GF??GIFFFBHI?AD4FBFIBFAIB?E?GGCIE?>BCI?CF?CHA@DC?IC?GACFDI@?
@>chr21:9691029-9691181-3
GAAGGTCCTCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCGGGCACACCCTTGCAGAGGTGGCCGGTTGCTTTTTGAGCCAGCCTGGCCTTCCTCA
+
CHFDCACACA?AGIA?AHBEGDHEDFIIEBCHF0IFF@GCEGHB-EEBFCHGGAEHDID?ECIBHCFBFG?GDBEGCFIEAHECGE@CFHE@AG@D@ICF
@>chr21:9691029-9691181-4
GAAGGTCCTCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCAGACCCTTGCAGAGGTGGCCGGTTGCTATTTGAGCCAGCCTGGCCTTCCTCA
+
CBFBICFB@EEIFE@@HBAF@FI?@@AB.HB?AFIFECEHA??HCEHAG.ACIBH@@EAE?HAFHAAAFH?HEF@IB@FDIDEFDAGADAH@HCEHAHDF
@>chr21:9691029-9691181-5
GAAGGTCCTCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTATTTGAGCCAGCCTGGCCTTCCTCA
+
HHED?GEG??DGHHABC?C??GI@AGIHCI??AEAIBBBG)BFAIHDFFAIA?E?BD@B@DBACBB@BCICFCBDBD?C@@BI@CEHHCIA@@IE@CFA?
@>chr21:9691029-9691181-0
GCGGCGTTCTGCTCATTTTCTCTGTGTGGCTCCATTTGTCTCACAGTTGTTGCACTGACTACTGCATACTGAGGCAGGCCAGGCTGGCTCAAAAAGCAAC
+
FD@GDG?8?DBDHG?IE?HAIGEFE?HCEAHIHDCFBFC%AIBG)EDACFHIEDDHABA@A@??BEEHHFAHB?.@BBD@BI?EDHA?HBII?CDIDCGG
@>chr21:9691029-9691181-1
GCGGCGTACTGCTCATTTTCTCTGTGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAAAAGCAAC
+
C@GDEAHIHCCFFFHFCAED?D?AI@H@CGABADFADC?EAEGB?@G@C@@@F@BDAD@GAAE?F@FA@@FA@FHEIH@BDADAFEFF@AFHDF?ICCHH
@>chr21:9691029-9691181-2
TCGGCGTACTGCTCATTTTCTCTGTGTGGCTCCATTTGAGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAAAAGCAAC
+
)F@HDBE@HCDE@@G@AEIGEIIFHB@?FCG@DGHAHE,CAIEEFDIECIDEDA?GDA@BCF?@CGGAIG@FBHFH?BECEABF@FIBFDBGEGCGI?@D
@>chr21:9691029-9691181-3
GCGGCGTACAGCAAGTCAGGTNGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTTTTTGAGCCAGCCTGGTCTTCCTCAG
+
G?FBFHEF%F?CH?AFIF??@.HHA?GCF@GG@AE@HBB?D?IIDHAHIAICA?DEIIIHC@?FDG@BB?CGDCHHCB?A?FFBEADBDG5C?H@EI?GC
@>chr21:9691029-9691181-4
GCGGCGTACAGCAAGTCAGGTTGGTGGTTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGNTTTTTGAGCCAGCCTGGCCTTCCTCAG
+
FE?GGCHF?IHF?AEI?AFBBCHCFID$HIH@BGFDGG?HEEIFICHB?CC@?CEGICAHCFHBHI@EBDDH"@AEBHIIIBDCIDC@FFDBHI?7@DGA
@>chr21:9691029-9691181-5
GCGGCGTACGGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTTTTTGAGCCAGCCTGGCCTTCCTCAG
+
HAC@DABA9<CGABEECFFDACEH?HGFADBECIG@@HDCIEBBAAFFGG@?EDCEBCFCBIECF@IC@D?FI@@GF?BFCC?F?AECFFCGGHC@FAHC
@>chr21:9691029-9691181-0
TCAGACGGTAATCTGCTCATTTTCTCGGTGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTAATGCAAACTGCGGAAGGCCAGGCTGGCTCAAATAG
+
?GF@IHH@?I@DEDA@BEGA?GGG?A"CB@@GEHIBEFIHE?HABCH?BHGH?@CBEBB??A@A?"EAGG"AA@B:????IID?FEACEFHBGIHH@C@C
@>chr21:9691029-9691181-1
TCAGACGGCAATCTGCTCATTTTCTCTGTGTGGCTCCATTTGTGTCACAGTTGTTGCACTGACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAATAG
+
IB?IBCDA4AEAIHIDGIA@C@HDFIDAHF@I?CDFGHDA@GBH@@CA@@5?HAH?E?HA@?EGA?AGEICD?G@@@IBEFCIEFIE@BCBB??EA??AI
@>chr21:9691029-9691181-2
TCAGACGGTAATCTGCTCATTTTCTCTGTGTGGCTCCATTTGTGTCANAGTTGTTGCACTCACTACTGCATACTGAGGAAGGCCAGGCTGGCTCAAATCG
+
AFECGCDFHCHFG?H@GHGCIHFEDBFIAFHGGH@A@B?CDIIAID@7ADEGHICIBII@%B@FFABDG?BECIIAEFFGCDGBHC?AG?@ECCBGGH<B
@>chr21:9691029-9691181-3
TCAGACGGTAATCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTATTTGAGCCAGCCTGGCCTTCC
+
@I?DFAAEG@EFFHAAG?IFIDCD?FFCFG?FCHCI?FE@?ACFF@@?GGDCFF@GHBD?CB@F@C?GA@ICDIHAHEIHECDIHIEFBFBHBCIBDAC?
@>chr21:9691029-9691181-4
TCAGACGGCAATCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCNTGCAGAGGTGGCCGGTTGCTATTTGTGCCAGCCTGGCCTTCC
+
C@?DI?FH3A?@G?GBGAD?CCHCGA@I@@ICGBHFHCIGIDIC@CDHC@F@@@@IG:ADEB?+AIBEB?GFH?E@B@B?ADH<@?HEFEEGF@BBHEHE
@>chr21:9691029-9691181-5
TCAGCCGGTAATCAGCAAGTCAGGTTGGTGGCTGGTCCACCAGCTCCAGGCACACCCTTGCAGAGGTGGCCGGTTGCTATTTGAGCCAGCCTGGCCTTCC
+
AHDE(ABEABDIB?BC?@DBHHFID??E@D@@EII@EIBEADEEGEGE?EE@GDF@?FFABCD@E?@?BIBC?@A??C??FADIECE@DEGH@HICBAAG
@>chr21:9691178-9691277-0
ACCACTATGTCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGGTAGGGCCACAGTGCTATCTGCTTNTCCTTAGGCCTCTGCTCCATCAGCCATC
+
BBIICDCGB@@?DBDEEDBACDHCAEEFGIBAHCCHIE@GECIDFIBICCBECGCG??BIF@CFFII@??H)G@CBIII??AFHCE@DCAGCEHAEGFIA
@>chr21:9691178-9691277-1
ACCACTATGTCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGGTAGGGCCACAGTGCTATCTGCTTTTTCTTAGGCCTCTGCTCCATCAGCCATC
+
AABHFI@BFBAIEDFBID@@IGDH?EHBEDGFHHCDEFGBHEECDICFIH?D@I?BHGI?FGEGBBHIFCCGA.B?@??EACCAFIIF@?H@??DCAHAA
@>chr21:9691178-9691277-2
ACCACTATGTCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGGTAGGGCCACAGTGCTATCTGCTTTTCCTTAGGCCTCTGCTCCATCAGCCATC
+
GIHADBC?B@G?IE?ED?DCFGIABBG@?@DCCGCEIA@ADD?G?AG??FEFFAED@EAA?DC@@IG@CEHBDHHH?B?B@HBG@?F?EFDG?@EEHHGI
@>chr21:9691178-9691277-3
ACCACTATGTCTGCCTCCTGACGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTACCTGTAGGGTAGAAGAACTGATGTAACCC
+
AEAAGBHHG??HADH@CBICD0FI@IA?@AAEHFIF?HH@E@E@HBI@IG@BDE?CID@GCIDGHEGHEBGEFACAEBFAHAAI@CCEE@HF?A?@DEI@
@>chr21:9691178-9691277-4
ACCACTATGTCTGCCTNCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTACCTGTAGGGTAGAAGAACTGATGTAACCC
+
I?DCGF@AHBAHBB?F2CF@GEAHDHH@CGDBBCHII@G@BA?AB@BIEBEFFC@DAEAEDE?C@?DBFDBC?FCHI@HG?@BG?A?DEBCCFCD@IEHA
@>chr21:9691178-9691277-5
ACCACTATGTCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTACCTGTAGAGTAGAAGAACTGATGTAACCC
+
F@E?@HBD@ECHBDDA?@HICEFEIBHFH@FDCIAIGDDID@?IGC@?A@FHHIAFEFB?DIDCBGGDHFIIICAGFF+?@EIFIIIGCAHEHH@FA@IB
@>chr21:9691178-9691277-0
CTCGTACCACGCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGGTAGGGCCACTGTGCTATCTGCTTTTCCTTAGGCCTCTGTTCCATCAGCCAT
+
IC@0@GABB@ADCAHHG@ACBIDHE?DC@@DAIIAG?IF@DGGBCCI@CHDFDDF?BB9DDCE?FB?@GAHGHC@FGI@D@DDD?GG=HCFAIBBHIFHH
@>chr21:9691178-9691277-1
CTCATACCACGCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACANGTAGGGCCACAGTGCTATCTGCTTTTCCTTAGTCCTCTGCTCCATCAGCCAT
+
FEA?FAGDFGAH@DCHIGFABBHFD@CHCFHFE?ACEAIEHBGBICH1HIAA@@FG?EBCEGIAG@B?CACGDDE@BFHF)C?EC?BHGDEB<@B@?@?I
@>chr21:9691178-9691277-2
CTCAAACCACGCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGGTAGGGCCACACTGCTATCTGCTTTTACTTAGGCCTCTGCTCCATCTGCCAT
+
DF?G;CF?B@F?GFGB@DIFD@B@CHBC?FDC?FEGHHII@F@AE?I@HDIE?@DFFHH(AC5HEB@I@HG@CB>GBE?IFCFHGDAB@BCBDB7?CFAF
@>chr21:9691178-9691277-3
CTCATACCACGCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTACCTGTAGGGTAGAAGAATTGATGTAACC
+
G?HIIAC?@FAB?CAEGEBGE@C?GE@@ABCFE@?AG@GHFEADBBAID@EFB?C%DEEBAEBCCIBCCCIBDAD?A@BGBC@BGFGB@$DDGFC?BIEA
@>chr21:9691178-9691277-4
CTCATACCACGCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAATGCAGATAGCACTGTGGCCCTACCTGTAGGGTAGANGAACTGATGTAACC
+
CGDDFDH2HG@GBGBFCDGBCGCBBEHAD?AFACIBAGCCF??HAGFIA?0CD?IDCFCD@@ADGFI?FCIH?AFEC@IDABHFF/HE?AHEBEBFAEBE
@>chr21:9691178-9691277-5
CTCATACCACGCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAANAGCAGATAGCACTGTGGCCCTACCTGTAGGGTAGAAGAACTGATGTAACC
+
@IEBBG@H@B?@EA@EDGAD@GIACI%GBDD@FHB@B@FFD@E?HAC?G;HFD?@GFHA.B@EE@D@HAIEG@?GGFHHDHEFIDHF?FHD?@BDG1AIC
@>chr21:9691178-9691277-0
GAAGGTCCTCTGCCGGTCGGGTTACAACAGTTCTTCTACCCTACAGCTAGGGCCACAGTTCTATCTGCTTTACCTTAGGCCTCTGCTCCATCAGCCATCA
+
GDEF@IF@DAHAFHFDEGB?GGHIFE,I@AGBEHEEI?BECBCCIB@?ICFCFBIGHAB:IDFC@ADBGBC5GEA@HCGDI?I?CABAHID@A?CI@HID
@>chr21:9691178-9691277-1
GAAGGTCCTCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGCTAGAGCCCCAGTCCTATCTGCTTTTCCTTAGGCCTCTGCTCCATCAGCCATCA
+
EGHFDGBEIDBEBDAFIFFGDDIH?GBHDI@C@D?FB@CG@GAFFHGI?B&GCB;BBCF2@@GDGIEBF?HDBGEG?CBE@?FCDCEBBFCBEBCAIAIC
@>chr21:9691178-9691277-2
GAAGGTCCTCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGCTAGGGCCACAGTGCTATCTGCTTTTCCTTAGGCCTCTGCTCCATCAGCCATCA
+
@EBE?BDBCD2FGI@GE?EFFGAHDADF?@EAGH@HF?G@BBG@AAD?GG?A@?AFFCHCFAFEBC?GHFEBECCAIDD@HAF?IACH@ACE?BGGAEAH
@>chr21:9691178-9691277-3
GAAGGTCCTCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCNGATAGCACTGTGGCCCTAGCTGTAGGGTAGAAGAACTGATGTAACCCG
+
AHCIHAFAFHFCH?F??H?AEBHF@AIFCGBFHIB@AGH@IE%ACB@?GCG(ICFEGEF?BHHIEE?F?FFI@AHEAIEGDDHC@GAEHFCCI?@FCFBH
@>chr21:9691178-9691277-4
GAAGGTCCTCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTAGCTGTAGGGTAGAAGAACTGATGTAATCCG
+
FICE?FBHHCI?BAABGEIDDGCGACFBDI@CBIACEHDE@CDIB?F?BID@@DFCFADFDFBHDB?7EBB?HFHI?FCCGE?I@CFGDB?IFIAG"A@G
@>chr21:9691178-9691277-5
GAAGGTCCTCTGACTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTAGCTGTAGGGTAGAAGAATTGATGTAACCCG
+
DDEEICHAAEG@;?@GA?CDFHFHA??BIAHE?DH@D?A@?BBHGCHHABH?GBBH?C?GHICAHDHE?D?EFEAH?HI@EEEECBG5EAC@DDGEDIAA
@>chr21:9691178-9691277-0
GCGGCGTACTGCCGGTCGGGTTACATTAGTTNTTCTACCCTACAGCTAGGGCCACAGTGCTATCTGCTTTTCCTTAGGCCTCTGCACCATCAGCCATCAG
+
DFEEDAB@@CE?GC@HAC$DADEFIA-A@CE$GHBCDHGFBIEE@@HDG??BEGCGFID?BDGEIHEDHDGBBDBDACIF@CGBI%H?A@EHDFEIB?FD
@>chr21:9691178-9691277-1
GCGGCGTACTGCCGGTCGGGATACATCAGTTCTTCTACCCTACAGCTAGGGCCACAGTGCTATCTGCTTTTCCTTAGGCCTCTGCTCCATCAGCCATCAG
+
DBA@IG?FCFEGBAIBIGCB,@HECI?GCCEGDDDBC@EHGBD?IGEDCCDDBIGAEGBE@A?GBAHIED?HADHBIBCBHCGICC@?IGI?AE?E?@@E
@>chr21:9691178-9691277-2
GCGGCGTACTGCCGGTCGGGTTACATGAGTTCTTCTACCCTACAGCTAGNGCCACAGTGCTATCTGCTTTTCCTTAGGCCTCTGCTCCATCAGCCATCAG
+
CA@IFGGICBECDG5D??ICCBFICG.FBE@FABIBECDIH@FIGDFA@'BCCAHCEH@DCCFFGBFC?HBCBB?IGBIFHCH?EI?CFBIDFDFFF?GH
@>chr21:9691178-9691277-3
GCGGCGTACTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTAGCTGTAGGGTAGAAGAACTGATGTAACCCGA
+
@DDDDDGHHICI?FACHCFAGDG?AGCDAB?@AFEH@A?FBDHGHFHIF@@DABB@BBDBFC?FECDH?@GABCF?FB?F?IFI@AE?FDBDECF4DDG@
@>chr21:9691178-9691277-4
GCGGCGTACTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTAGCTGTAGGGTAGAAGANCTGATGTAACCCGA
+
EDCABEGI?CHAFBHB@A?HB@H?@EDIHF@CC@@EF@BFI?CBB@HGCFAF@FIFCCCAHHI?H@GIAAFCEF@AIADHHCFFD2FHICBEDADBCFDD
@>chr21:9691178-9691277-5
GCGGCGTACTGCCTCCTGATGGCTGATGGACCAGATGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTAGCTGTAGGGTAGAAGAACTGATGTAACCCGA
+
C?@HHBB?@@GFIC@@@@EFEFEHHEGEFA>H@E@*H@@&ABDAECCFCHEHIAGCB?DIAHIIIAFHFCDBEH@@BDDHF?FBHEBGECEHC?@EBDAE
@>chr21:9691178-9691277-0
TCAGACGGTAATCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGCTAGGGCCACAGTGCTATGTGCTTTACCTTAGGCCTCTGCTCCATCAGCCA
+
?B?@DBCCGBE??CCI@HIB?AGBCIF@HIHFGHIII@GA@DGHFH@EIEB@AF@EHEDI?@HA@FA#@G@EBA>HDE?A?ABD@DFCIGBGG@@EHGGE
@>chr21:9691178-9691277-1
TCAGATGGTAATCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGGTAGGGCCACAGTGCTANCTGCTTTTCCTTAGGCCTCTGCTCCATCAGCCA
+
A?FHA.HDAFIIAB@IFHI@FIEIIFHEAGBAFH?IIEDBBHE@EGG?B@H?CBHB@CB?BCH@B@8HGEFHBBCA?IDH@HIG?EGBC@IFGC@EECGD
@>chr21:9691178-9691277-2
TCAGACGGTAATCTGCCGGTCGGGTTACATCAGTTCTTCTACCCTACAGGTAGGGCCACAGTGCTATCTGCTTTTCCGTAGGCCTCTGCTCCATCAGCCA
+
ABCH@FIGI@CIGBEBCGI%DEHEAHDFCGE@BEBCHFACCGBDD@?AHEAIHH?DDHB?C?GAF@EGCIHA?@IF?$GFIGCBDD?FAHIB?G@@H?EB
@>chr21:9691178-9691277-3
TTAGACGGTAATCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTACCTGTAGTGTAGAAGAACTGATGTAAC
+
@.GEBA@BCC@@DEI?FD?DBEBBEC?CCBFDDEBFE@D??@??GB?C?@HBCBBAAD@?EFCCB?EAE@GGBIGEH?DH.DFHDHCGC?IFBI?HHGE?
@>chr21:9691178-9691277-4
TCAGACGGTAATCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCCCTGTGGCCCTAGCTGTAGGGTAGAAGAACTNATGTAAC
+
BCIH@BHCCDFIDFEDBBEAGAHCCD?D@HCBE?@ADGFFIIE?DC??H?GAHEIDHHEI?9E'G??E@?G@@IICDIADI@F?G?B@CI?D*CHGFG@H
@>chr21:9691178-9691277-5
TCAGACGGTAATCTGCCTCCTGATGGCTGATGGAGCAGAGGCCTAAGGAAAAGCAGATAGCACTGTGGCCCTAGCTGTAGGGTAGAAGAACGGATGTAAC
+
DDDBDEA?DBH@FG@CIDHG@CAC?@@@CFCDD@CC?C@HAFGGF?IDICEEDDIBHGCAIBE8AAHEBBFFF@DHHCIHCIIGACDCCHE<@EI@CEHD
@>chr21:9691274-9691376-0
ACCACTATGTCAGCCCCTCAGGCTGTAGGAATNTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCGCCTGCTCCAGGCACACCCTTG
+
DGE@AAH?B?FD@@BDGBBBFGHG?IE?CB@C'H@IEHACBIIAFB??GADCADFFI?AG?BGF?BI@DHFEIGGFAB#IBFECIGDIB?EB@@ABHEFE
@>chr21:9691274-9691376-1
NCCACTATGTCAGCCCCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTGAGTGNGTGAGGTTGGTGGTCGCTCCACCTGCTCCAGGCACACCCTTG
+
7DHDAEIDBC?DIGCHBF@AEHEH@BHDDDHHEBFFIFBA@IEIBB???FGHC?IA?5CEIFDHI?GBDC@A1CEB?D@ICCI@I@ICA?EDBCGA?GDE
@>chr21:9691274-9691376-2
ACCACTATGTCAGCCCCTCAGGCGGTAGGAATCTGGCCATCCCTTCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCTTG
+
@BHDHFGDEDFE?@DDGB?1?GI>ADHEDEID@EHHFH?AEECH+?HDDCDIGCBDGAHI@?HF?FFHGGCEHECD?HCAE?BF@?FGCA?IB)IA@?F?
@>chr21:9691274-9691376-3
ACCACTATGTCAGCCACCTCTGNAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTAACCCACTCANGGAAGCAGCGATGGCCAGATTCCTACAG
+
AIDIBI?AIFDIEE?IB?@@GH+IDI?@FB@EGB?AHBF@HHCFEHCAABCAAB?ADICAI(DAIGIHG?F)EBFABH?B(CBBC@D??BI@HCG?EGFA
@>chr21:9691274-9691376-4
ACCACTATGTCAGNCACCTCTGCAAGGGTGTGCCAGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTACAG
+
H?F?I?D@EFHBE4IFIIIEEF?DAIHGAIIAGA=CDI@?IHGEEA@EHGH@AFADAFH@EBC@GBDCBCDGFD@IF@FAAHBHCFFCGDEI?FDEEA?F
@>chr21:9691274-9691376-5
ACCACTATGTCAGCCACCTCTGCAAGGGTGTGCCTGGAGCAGGTGNAGNAACCACCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTACAG
+
HCDD?EHHGDEAFEHEIBA@IHEIB@F?DDDCIDEAIFF@HFFBF6CB(?HIG@H?EB@CAICFF?FFAH@CHGHB@AFFEF@GG@@EC?FAIHFH@GIB
@>chr21:9691274-9691376-0
CTCATACCACGCAGCCTCTCAGGCTGTAGGAATTTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCTT
+
G@F?CHFIHBFIBBB@0H@@CAEHFB?GH@HA?%HCIBIDHGDFG?CACD@?A?BFDFBIGDHGFADEHFCC?HIFCFHBFC@?I?FIHDHF@IDDEG@@
@>chr21:9691274-9691376-1
CTCGTACCACGCAGCCCCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCGCCAGGCACACCCTT
+
FBB$@FDBG?AHICCCHBEABHIDFEIFHHGA@GCBF@GAGIC?@G?EHICCBHGCDCGHIA?H@F?GH@FD?EDDFC?BI@IEA-BGHEGC?ABHAE?B
@>chr21:9691274-9691376-2
CTCATACCACGCAGCCCCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCTCACCCCT
+
HAFBGAGGAGAHFDG@BDAI?FGDE@GE?@FAHBIHED?CFCCEGDIEIFGE?@AEBBGHCBE?GCAGEIBHBDGFBHBGG?DFGAFFE?HE1CBDCI&G
@>chr21:9691274-9691376-3
CTCGTACCACGCAGCCACCTCTGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGNTGGCCAGATTCCTACA
+
E@E:HAHI?BI@AHFBIDGBCEEFHGICBAEB?A@EEIHAG@BBFGCIIBEC?BABGFCF@DAB@FHIDGDAIIFADCICB@D5IIH@IIE?GIBEIF@E
@>chr21:9691274-9691376-4
CTCATACCACGCAGCCACCTCCGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAAGCTCACCCACTCAAGGAAGCAGGGATGGCCAGATACCTACA
+
?F?GGGFB?HHB?BDCCHEH@3A?IFHGFCGHIFGGCIDFIDECCBAFHBAFAH@@?FA8GABEIGHBGGGA?ADBEEAFDDG@HCHD@FDHG&B?IGD?
@>chr21:9691274-9691376-5
CTCATACCACGCAGCCACCTATGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTACA
+
6DAAE@EH?C@GIIFH@ECG4?FGDDB@EHFI?FHHDGDBEGGFGEHB@I?EID?C?HEA@@F?FA?F@FIAEIIGDHC@EE@?IBGCB@D@HEGB?FAB
@>chr21:9691274-9691376-0
GAAGGTCCTCAGCCCCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCTTGC
+
DDCEGDE@CC@HEDCEABFEBA@C@IDGAFCIHCEE@AI@CFE@EBFEDDHAAHGICAIGEAAFID?DIFBB?D@D??BBBBH?BI?BFDEDBGFH@GCE
@>chr21:9691274-9691376-1
GAAGGTCCTCAGCCCCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCAAACCCTTGT
+
BAEA?IEBCCG@@?EGFHADFIHGHFFFBEFIDIFIEFA?FIBGEEBDIEAAGBGGABDHFBCFHC@FDHABI?DEFGCIBGHG?BBICII;FHAHG??"
@>chr21:9691274-9691376-2
GAAGGTCCTCAGCCNCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCTTGC
+
@?DC@D@FBDFHDC*IA?FFFAGC6EACIEIH?HB@HGDAF?CA@AGCAHCEDGFECAECDFEDDAADHFE@BDC?AEFA@IGCFC@CCC@GEDEH??HE
@>chr21:9691274-9691376-3
GAAGGTCCTCAGCNACCTCTGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTACAGC
+
@@DDACEEC%IBF4BHB?FC?A?ADBADBBDBHCFBBFHEIFH@EGHAIBH??@DEC@GIGGBDBICCEFIDEFECCG?IFDBDGHBAHHFDHHHEIDBH
@>chr21:9691274-9691376-4
GAAGGTCCTCAGCCACCTCTGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGAGGGCCAGATTCCTACAGC
+
BEBA??+FBIGGE?HEC?DHHG?@BHHE?EA@D@BGFEGDBE@ICBHBDGDBDGGIFGFD?@?I?FDDBGHFBDHGAA?I@E6HEHFHEAGCFICA@I?B
@>chr21:9691274-9691376-5
TAAGGTCCTCAGCCACCTCTGCAAGGGTGTCCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTACAGC
+
2G?ECCGHCIIG@HBBBB@AF@CBHGBGCB/AEHABEIGGHHHBDFEGFDABFAEGGCHGEDEIIHGIEGFE@F@F?HEAHBI?EACBAFG?FC@?@BEE
@>chr21:9691274-9691376-0
GCGGCGTACAGCCACTCAGGCTGTAGGAATCTGGCAATCCCTGCTTCGTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCTTGCA
+
@ADB@HFEGHCFC6HI?BC?ECBIFHHC?BIIGEHCGCCIG??@DHF,AG@EA&CAAIEC@DIEDEBAIABGBAAE?HGDABCADDGBBG@H?IHHGGHD
@>chr21:9691274-9691376-1
GCGGCGTACAGCCCCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTTAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCTTGCA
+
BIG@CDEEACGFEFEGIGH@AA@@AI@?ABDAAA?EB@HHCGAC@C@HEF'EC?C?HIH?BHCD@HBCFHIHDDBCDIG@@BAG@AAD?DED?@@AGHBA
@>chr21:9691274-9691376-2
GCGGCGTACAGCCCCTCAGGCTGTAGGCATCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCTTGCA
+
FF?BEICG@I?DA?@G?HIEFIIGFEE)HFBBD@CE@?GEID?DDEFAB@FG?GHBFB?H@EBCEGE@EB?ECDHFHB@AIBI@E??EC?HHEECDAGCE
@>chr21:9691274-9691376-3
GCGGCGTACAGCCACCTCTGCAAGTGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTACAGCC
+
FICI@HDCC?EBE@HAGDGEAADD1DCGCHAD?BE?BCIH?DEGAHAGD@@AHDCGEDF@AB@DAAGDIBDDE@EC?IEHBBCECDIBFFIHDDB;???@
@>chr21:9691274-9691376-4
GCGGCGTACAGCCACCTCTGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGATTGCCAGATTCCTACAGCC
+
HICHB@AEBHDACA@?ABCDHI@EIBF@AIHDF?BAGBACHB@@BH?AFEBFAI@A@B8FHCDGIGHECBAIGCBAEB@IHFIFD;FIICCIDI?EAFGF
@>chr21:9691274-9691376-5
GCGGCGTACAGCCACCTCTGCAAGGGTGTGCCTGGAGCAGGTGGNGCAACCACCAACCTCACGCACTCAAGGAAGCAGGGANTGCCAGATTCCTACAGCC
+
F1?GBA@@>GBBDA?CDFACCIHFGGEAI??CB@HAGIAHBEBD7DBH@?AIFAF?ABFFBF)@@HEDD&I@IIHCBIIEC)?AA?EEDE@AGG?@CDBC
@>chr21:9691274-9691376-0
TCAGACGGTAATCAGCCCCTCAGGCTGTAGGAAGCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCT
+
IG@BGCACBE?B@EEAG@IGDFHAAICDD@?AH=IEAAFH@?I?CHGGBHDEAA@AABD@@IC?EFIDFCADEDIAFBCFH@H?H?@CCEIHCIAGA?FD
@>chr21:9691274-9691376-1
NCAGACGGTAATCAGCCCCTCAGGCTGTAGGAATCTGGCCATCCCTGCTTCCTTGAGTGGGTGAGGTTGGTGGTTGCTCCACCTGCTCCAGGCACACCCT
+
(DDHCGDCIBGDADBFFHEHGBAHHCBEDDAD@DBGBEDGH?DFCBA@GD@?BG@HFGGEEA?A?HB@DB??BFDC@?BAFEEABE@?BFAIECI@EEHH
@>chr21:9691274-9691376-2
TCAGACGGTAATCAGCTCCTCAGGCTGTAGGAATCTGGCCACCCCTGCTTCCTTGAGTGGGTGAGGNTGGTGGTTGCTCCACCTGCTCCAGGCACACCCT
+
GIHCIDCC?DAID@G@<?EA?FAG?DIDBBHH@A?GFAECE<IDED@@FCCEHBE@AI@DI??GAF&F@@IEAHCH?C?I?AADB?GIBCFCFH?CAA@E
@>chr21:9691274-9691376-3
TCAGACGGTAATCAGCCACCTATGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCATCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTAC
+
<@@ADHHGF?ABI?@IICFCG5EBEDCD@BIED?D?FCB?BADA?CDFGFH@HEEA:GEGECFFBGEGF@DEEHCEBHDE?HHCDFEEBDGFIIFBFAAG
@>chr21:9691274-9691376-4
TCAGACGGTAATAAGCCACGTCTGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCACTCAAGGAAGCAGGGATGGCCAGATTCCTAC
+
H?HEEEDCAAFG6?CI@HB(CHHDBCFGFFBEDDHGHGI?BDEC?D?EEFFIGCDDFHIG?IHF@BG@I?FACGFIIAEEBEEEIDB@AA?@FAHABCAI
@>chr21:9691274-9691376-5
TCAGACGGTAATCAGCCACCTCTGCAAGGGTGTGCCTGGAGCAGGTGGAGCAACCACCAACCTCACCCANTCAAGGAAGCAGGGATGGCCAGATTCCTAC
+
@IEEI@?DCG??FDCCEE@CCDCCFGEGDDBEBFF@?DFGHBFE@IHHB??AEDIIIIE@@CH?@HEDF:DDHIF@CBBFHCAFEIDAIGGHIIDGC@AF
@>chr21:9691373-9691527-0
ACCACTATGTCTGCTTGCTCTTTGATCCAGGTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCTGCTTGTAGTGTGTTG
+
HGGEGEIEH?A@HGA@EHCB?HE?GAHBFE@CI?H@CC@?DGDDFDFFCIABB@H@BDDEAGFG?HD?DDD?@ACAADEGG@GC.HF@IH@AAAHIEE@B
@>chr21:9691373-9691527-1
ACCACTATGTCTGCTTGCNCNTTGATCCAGCTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTNTTG
+
IGIHIAAEGGEBBIEGC?5F%BAHBEGGIICBIG?@GE?EBFDEAEC?H??AACIDFGDBCDDEAFIB@DHH?FHCDDD?FFIAB?DAH?EECHCG7DCD
@>chr21:9691373-9691527-2
ACCACTATGTCTGCTTGCTCTTTGATCCAGCTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTGTTG
+
EEFI@@??DABAF@ED?ADD@GHDCA?BHFCAIEF7FD??AI?CCCHIA?B@ABHHCAIAEDIFDDGBABCFAEDEFEEDIF@GIDCAB@FAEGDGGCED
@>chr21:9691373-9691527-3
ACCACTATGTCAGCCAGGATTAGCACCCAGGGAACTCGGCCTTTTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACTTGGAAC
+
DCBCC@EABDHCCGE@IACBCG?DA?DFCFGI2B?DHC?F??G&EBFACGDABD???C?IF?ACDBGA??B@ABHBAGDHF@IDFGG?BBFBAC@BCCIF
@>chr21:9691373-9691527-4
ACCACTATGTCAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACATACTACAAGCTGCCTTGGAAC
+
@F?ICFE@EACICFAGDHFDDGDCDHHGGE@H@GHFIFECCC?GGHBHBEBABH@IHD@BEHIEBIAIAEBD?C@F@AA>DGDC@FH@DCG:GFFICCDC
@>chr21:9691373-9691527-5
ACCACTATGTCAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACTTGGAAC
+
D@DHDAHCE?@GFFBA@H@HAEFE@@?E@BAF@EFBDAGDC@BD@?DEGGDHHFCGFIIG@@CACBE??GAAFAHCAH@I?BEGAG@IAD@FGE?H@EA@
@>chr21:9691373-9691527-0
GTCATACCACGCTGCTTGCTCTTTGATCCAGGTTGGCCTTGCCTGGCATGCACAGGACCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTGTT
+
-GCDHEFI@CFFGAIGHBB?IGHHGAFG@B?HFC@?BGBCBFCHEGDFAI@@HBDF!FAE?IG@B@BEHE@HFECCB@EIHGAB@AFGBEGIAGFDCGBE
@>chr21:9691373-9691527-1
CTCATACCACGCTGCTTGCTCTTTGATCCAGCTTGGCCTTGCCTGGCATGCACNGGCCNCAGCTACCTATATGCCGTTCCAATTCAGCTTGTAGTGTGTT
+
@?CAIDHIGHDEDAFCAC@B&@IHAFBFF@H?BE@ECBCI?H@B@@BBF@E@B1@IEA:B?HCA?D@GFEDGBCA@@BC@F@/@@EICBBGIGAFG?C@A
@>chr21:9691373-9691527-2
CTCATNCCACGCTGCTTGCTCTTTGAGCCCGCTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTGTT
+
HGA?F"AC@@BF@D?E@GDADDB@?A>HE<H@HACCGHDGHGDCFHGEHHBDIFADBAF@ECF?EIBIGCBBD?@AH@@B?DDHECE??D?D?AFI@ACH
@>chr21:9691373-9691527-3
CTCATACCACGCAGCCAGGAATAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACNAGCTGTCTTGGAA
+
FIGEI?HGDCG?AAA?BH?G0E@I?HAICBCEHE?FEHCEH?HFBIGBCBGB?B@H@G@G?AEBG?@HE?HDHBG@@A?D?GHIHB3CBIHA"HGCFFGE
@>chr21:9691373-9691527-4
CTCATACCACGCAGCCAGGATTAGCACCCAGGGGACTCGGTCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACTTGGAA
+
FDCAG@E@FIHIFFBCFDCBFD@FE@ACCCB@ACHG?IGC%CDEADBFDFAHHHFEDHA??B?C?GB@IDBFA@IG@CDIDHEIDG?G@I@H@?CE@AFB
@>chr21:9691373-9691527-5
CTCATACCACGCAGCCAGGNTTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACTTGGAA
+
BE?IIGHI?@BAED@F@EA>@?I@ACIIGHBGDGHFECACIEBB@GIICACDG?HCC??EBFDDFHDCFEFBCGEC??GIEHGEGCF??EE?@HABI@HF
@>chr21:9691373-9691527-0
GAAGGTCCTCTGCTTGCTCTTTGATCCAGGTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTGTTGG
+
CGDHEIFHHFFCDCADEDCDDBHCECGHG@DHCIIGA?ADAIGC?HEEI?@EBEAEB??BABHIG?HEHIHDCBGFEIABE?CFBIAFBDAGE@B?@HAA
@>chr21:9691373-9691527-1
GAAGGTCCTCTGCTTGCTCTTTGATCCAGCTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAATGTGTTGG
+
@E@HB@HF@CFDGD@E@FGGD?EDBDGAI?HFEB@@CFCGEIBCHD?BA?C?FGA@@HIG@G@HGHEGAF@BAEFC?CBEEHCHDDDAGIF6I?G?IEAC
@>chr21:9691373-9691527-2
GAAGGTCCTCTGCTTGCTCTTTGATCCAGCTTGGCCTTGCGTGGCATGCACAGGCCCCATCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTGTTGG
+
GF@GBAGACGAFEEBIEDBACC@ABIEGGACCGGE@DHGE(GCCAHDFFFB@FH?IFCF0CIEHIAHA@??EDEHFDGF@DDICIIFIGFD@BEG?B@BF
@>chr21:9691373-9691527-3
GAAGGTCCTCAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGNAGAATTTGGCCCAACACACTTCAAGCTGACTTGGAACG
+
@HBG@GCACGEDHF?CFEFIEIH@?GEBGIDBCDHHHEDGADCDBFAIFBAIH?EBBBHH?8?G?IG@?AFIF?BHH@G@GH6B?BEAI@HCAEA?G@??
@>chr21:9691373-9691527-4
GAGGGTCCTCAGCCAGGATTAGNACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACCACAAGCTGACTTGGAACG
+
FH+GIAAEI@?@AECDHBD?IG(DDI?BIGCGGAHCC?DIACCABACEHAI?IHG@GFEF?CCEC?IEIBD@?HBEHHI@I!BBEICFI@FAFHG@CEC@
@>chr21:9691373-9691527-5
GAAGGTCCTCAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACTTGGAAAG
+
G?@FCBBGHC?!GDG@EHDEGHCFC@C?GAAID?GIEAFGBHIBIGBF@F?D@?HBHHI@BCHFECEF@EHAAHIICFECG@EFICIDEGFDAIF@EF3@
@>chr21:9691373-9691527-0
GCGGCGTACTGCTTGCTCTTTGATCCAGCTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAATTCAGCTTGTAGTGTGTTGGG
+
AA@BAIHCGC?HACEHAD?FB@EEDBFIIEBI??BBG@GCAHFFFD?DC?DEIB?E@EI?GHHDBHHG?BB?@@H?AAG7AIHG@FDF@CFCHIECGACH
@>chr21:9691373-9691527-1
GCGGCGTACTGCTTGCTCTTTGATCCAGCTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTGTTGGG
+
GEDA?D@CD@CBI?IHB@DF?EEBCCIIGAHEDHG?A@C?IBAHI?ADGC@HGGDCBC@EEBAHIC?B?HFI?D?E@C?CADEHECCDGE@CG?@GIDFE
@>chr21:9691373-9691527-2
GCGGCGTACTGCTTGCTCTTTGATCCAGCTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTTTATGCCGTTCCAAGTCAGCTTGTAGTGTGTTGGG
+
?GFIBH?ABABEACI@EE@GG?CEG?DADE@IIGAEECDGICIHB@@H?CABHDAD@IIBDAG@@4ACCHCHDD@?IFFAIDFICGHCFDECCGEIECHI
@>chr21:9691373-9691527-3
GCGGCGTACAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGTCCAGAGGTAGAATTTGGCCCAACACACTATAAGCTGGCCTGGAAGGG
+
ECCDDGBFGBEBDD?EDCBA@FGICIAAE@CH@B?D?DCCHGHGEIIIFF?D.FCAICGHE@CBA@I@AGFIB@AIAEEGGF7BGGDFF(F"BG@EB0HA
@>chr21:9691373-9691527-4
GCGGCGTACAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTGGGCCCAACACACTACAAGCTGACTTGGAACGG
+
EHIEDFHEH@IGA@GDG??EAHBBFIDB@IC@DAHCDBCH@B?BFFH?DDCGHD?DE?@AGFHFIAB2EBIHBDH?AEBBHFCBFEEFEFID@EIB@FFG
@>chr21:9691373-9691527-5
GCGGCGTACAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACATGGAACGG
+
GG?BFDFBDC@CGDD@I?AFEHDEIGC@@D?@CEFHICF@FABHEG@EEG?CCB?IF?EHDFACEAABAADFGDFIHBFDHGBDB@CIBCD$FEAGI@GE
@>chr21:9691373-9691527-0
TCGGACGGTAGTCTGCTTGCTCTTTGATCCAGGTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAACTTGTAGTGTGT
+
H@+FD?FDH?6HA?BB@I@HBD?E?HBBDF?AAEFFEEACG?@E@@BHDFDHIBB?EFBI@GFBCIGICFCCC?GGGCHEIBCDDCF7G?@A@DA?AAA@
@>chr21:9691373-9691527-1
TCAGACGGTAATCTGCTTGCTCTTTGATCCAGGTTGGCCTTGCCTGACATGCACAGGCCCCAGCTACCTATATGCCGTTCCAAGTCAGCTTGTAGTGTGT
+
@@HAGFCHCHFGFBHFH?I@FBGFB@HGIH??HE?HIBBBA?IB@>=BAGB@IEBGA@I@GA@FDCHF?FFBF?D?GB?AF?G?B?BII@CD?GBAGC?@
@>chr21:9691373-9691527-2
TCAGACGGTCATCTGCGTGCTATTTGATCCAGGTTGGCCTTGCCTGGCATGCACAGGCCCCAGCTAACTATATGCCGTTCCAAGTCAGCTTGTAGTGTGT
+
???CCBA?C7+DI@CI"DIBF)H@FDDA@GGHH?GGBHHGCEFFIGDDCDHB?H@A?@HACGC?GG/G?IFIAGBE@BCC@BDBDD@EBEHGDHBG@BFH
@>chr21:9691373-9691527-3
TCAGACGGTAATCAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCATGGCCAGAGGTAGAATTTGGCCCAACGCACTACAAGCTGACTTGGA
+
CCACCA@?F@EFIGBFHE@HIEC?FHIECIBIGECI@DEHFAHFC@@DFDIAC!FIHHEBEGFDEDBAICB@G@FEBCCA0FB?EC?EACCHEBEDCHEI
@>chr21:9691373-9691527-4
TCAGACGGTAATCAGCCAGGATTAGCACCCAGGGGACTCGGCCTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACTTGGA
+
EEBFHF?CAIGIB@?DA@CICFC@BAEDI?EDBDGF?BICBAEIFIEC@BIE?D?ABIBGFGEFBA@AGEAA@IC?@F@?IGHAGCIA?GCBCABCE@@C
@>chr21:9691373-9691527-5
TCAGACGGTAATCAGCCAGGATTAGCACCCAGGGGACTCGGCTTTCTGTGGCCCTGGCCAGAGGTAGAATTTGGCCCAACACACTACAAGCTGACTTGGA
+
IDABCECBC?H?ID@GGII@EEGBDIA@FIEDFDBE?@C?HI$?EHIICAEDDFAICDA$?EDFDAGGH@F@AC@IEIHDB@A??B@HHECBBFG??HBG
@>chr21:9692338-9692458-0
ACCACTATGTCTGCTTTCTGCNCTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGTCATATGAGCC
+
HECIA?B?HEB@EF?EAED?E/?DB@CD@H@@EFEB@@BGI@@@GGFC??D@CCGEEBAD@F?FIBHF?HBECEIC@EDBHEB?@H!ECAIEEGA?EBAI
@>chr21:9692338-9692458-1
ACCACTATGTCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTTTGCCTCTTTGCAACCAAGAAGNCCGCAGTGTCATATGAGCC
+
DFABAG@BIED3??EEGFCID?AG@BBDFI?HEAI@BED@BA??AFFCFDEACHAEC;'CCE@IFH?A@F@CCGHHD@?B2FFCDCB?GIBCIDAACCFH
@>chr21:9692338-9692458-2
ACCACTATGTCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGTCATATGAGCC
+
@HG@EGHHCAA??BGGC@G@EI@EFDIIDIBAADB??DBH@BBHHHDEHE&?BC?GHDHD@BIAAC?A@CACBBIA@?GCEBA?AEAF?@CFIHGB?EIB
@>chr21:9692338-9692458-3
ACCACTACGTCTGCCTTGGGGGCTCCAGTCCATGACTCAGGGCTCATATGACNCTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCNCAGGCCATCTTCAG
+
CBI?BBG7I@@EHBAIC@DCIFFCCBCEB@CFI?8@H@F@DC?IA@D@?@CC,GDCGCDGBEBC?G@EAC?EI??CEEAEICA@D1ABHDHI@@@@DEIC
@>chr21:9692338-9692458-4
ACCACTATGTCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAG
+
HAFDCBIAAB?GBCAI?A@GGG@BGG?G@GG?EIBHBIBAH?FHBIHFI@HED@ACIIDEGBAA@F?C?B@GFI@DEIIAFEHDCAIHDBB@IHHGAGEI
@>chr21:9692338-9692458-5
ACCACTATGTCTGCCTTGGGGGCTCCAGTCCNTGCCTCAGGGCTCATATGACACTGTGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAG
+
@EF@@AB@CFECEIFC@DE@BF?ICC@BBEI)HFCCDEB@?HACG@DICG?HH?AF(AGEDGDGBCIDECCDCHBEIE@BFFADGBABID?A?HACGFHA
@>chr21:9692338-9692458-0
CTNATACCACGCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGTCATATGAGC
+
IG,HD@IEFFGIFCHABABHB@EBFGDAB?BBADF@HDGFEGEFDDFEEDAC?(H?BHHFHGEHBIFACHHEDIAGC?EDHFDICEG@G@EC?FCEIEAF
@>chr21:9692338-9692458-1
CTCATACCACGCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGACGGCCTGTGGGCTGCCTCCTTGCAACCAAGAAGCGCGCAGTGTCATATGAGC
+
ICE?CIEADE@@E@G?DC?CIG@HD?HHGFEBBA@A?GDA??FCGH??'@ED@DEEHF8CIHH?HE.?GGEA@IBDE?CDCC;GFA@I@IIFFHGEAAGH
@>chr21:9692338-9692458-2
CTCATACCACGCTGCTTTCTGCACTTCAAAATAAAGGCCTGCTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGTCATATGAGC
+
EIF@F?ABCGBIDAD?AHFAFFI@?BFABA?IEFHCI?AE+?FGICD?BEDFGED?@HGFC@GBD??IHHIFBE?ICHCGDH@B?F?D@HG@DDB@FHBA
@>chr21:9692338-9692458-3
CTCATACCACGCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCACATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCTATCGTCA
+
ABCGBEECDDIIE@CEAH@IAGEBI@FCDDBDHHICEFDHFA?GEG@5CGEBBEBCFH?DF@@@DCDHGDFH@@GE'C?GHAEA@AIAABBC3ECD%CDD
@>chr21:9692338-9692458-4
CTCATACCACGCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCA
+
GIFHBGFB@GGH@CA@EHHIIFAACDCCGHAAEIDCHCBBC?BHGBBGBHB@BB??EE@?B@@B@DEBFCD@@HICHEFHEFHGCCEHI@GEC@ACH@?B
@>chr21:9692338-9692458-5
CTCATACCACGCTGCCTTGGGGGCTCCAGTCCATTCCTCAGGGCTCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCATCA
+
DEDCIFFBHB?DDAFCHIGE@@@DI@@BGBCC@B8IBCAAFGB@GGFIBGGHACCBE@BDHFEGCFG@D?@CICAFC@GG?H@FEGH@EBCBCFEA1?AE
@>chr21:9692338-9692458-0
GAAGGTCCTCTGCTTTCTGCACTTCAAAATAAANGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCGGTGTCATATGAGCCC
+
IGDFBAGDBDBDDAACHBBH@GAIDDA?GCEIA-FFGECED@DBH?E@@EF?IH@BI?AEBEA@@BD?H@@?GEBA@D?AF?HI<FAID@FGIGIIIEGC
@>chr21:9692338-9692458-1
GAAGGTCCTCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGTCATATGAGCCC
+
HEBEEECE@G@HI@FHGEADGEEIDDAF@A?@EEDFFCAFGBB?CHIGAGDH@C?FDHEEAFEA@C?GBBGEIDCEHGEDFH?CFGCFGCEDI@BEE?GI
@>chr21:9692338-9692458-2
GAAGGTCCTCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGAGGGCCTGTGGTATGCCTCTTTGCAACCAAGAAGCCCGCAGTGTCATATGAGCCC
+
EBDIA?@ADGHEGBI?GGCF?GHA?IB@C?DAG@AFBFGF@FHCGG9BBIDD???CG&AEF@CCAID?HIDADHCIIEE@BEDFAHE??HHAEFFDDCAF
@>chr21:9692338-9692458-3
GAAGGTCCTCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAGG
+
?BBA@@@GCEGF?DABG@EGE@@BEHHDIDFGBFCDEDBGF@ACAIF@BGHDFIAG?G?H?F?FGDBBGGEABEHBHCEHECGBBCID?GHIEAI?C?FG
@>chr21:9692338-9692458-4
GAAGGTCCTCTGACTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAGG
+
AI?CCEADEDCC:B?@@DDHEFEIIAIIEDBFAIFIG?EBFHEG@HICCE@EDGF@G@BBGEHIFIEC?AE@IEAEACI?DFGBBBE@I@@IA@DI?@?E
@>chr21:9692338-9692458-5
GANGGTCCTCTACCTTGGGGGCTCCAGTCCATGCCACAGGGCTCATATGACACTGCGGGCTTCTTGGTTGCNAAGAGGCACACCACAGGCCATCTTCAGG
+
D?.HBAFCIFC5HH@BHFFAF@FBFBDDDG?EB?E$DEA??A@?@GDGFBFHFFIDABEABGBHED?CEHF"CH?@FBAF!BID@CFGDDACD@EAIH@I
@>chr21:9692338-9692458-0
GCGGCGTACTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCCGTGGTCTGCCTCTTTGCACCCAAGAAGCCCGCAGTGTCATATGAGCCCT
+
CAHA??CHCIE?GBIGGG@BD@HHHAHHA?E@DIFA@GAIGI?FAGCGAE'HI@?I@DGEC?EIB?BD@BGDC?FC@I?CBI?H@FBH@GAECE?GHIAH
@>chr21:9692338-9692458-1
GCGGCGTACTGCTTTCTGCACNTCAAAATAAAGGTCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCACCCAAGAAGCCCGCAGTGTCATATGAGCCCT
+
?EGI?DEHICB?AHDHAB@I@>EEIHIIBHCCAB=BIDGGBADABBHFB?E@?@HBEAIFBI?GCHFCGA?E?A?@IIECFAGI@HDGE@@@HDGDEHII
@>chr21:9692338-9692458-2
GCGGCGTACTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCACCCAAGAAGCCCGCAGTGTCATATGGGCCCT
+
?CDBDDB?FHEG?CDCGE@?GGDB?GDFBGCAEG@G?CFEAHAEHGAFHFDEID@GHGD?EBFFD?F??ICBICIFCHHGGAB?@DDIDAID@H$AIBDA
@>chr21:9692338-9692458-3
GCGGCGTACTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTCAGGA
+
CAAFEBCFF?CDFDF@F@CFD?GAFIF?EIHCEFGAAH?IACDD?CHAHH?GIEDGAHBIBFFAEI4@A?IEHAG?BIECIGCFFIIBCCIDAIAEH@GI
@>chr21:9692338-9692458-4
GCGGCGTACTGCCTTGGGGGCTCCAGTCCATGCNTCAGGGCTCATATGACACTGCGGGCTTCTTGGGTGCAAAGAGGCAGACCACAGGCCATCTTCAGGA
+
D?CD?ABD?HFB?EFCIB@GGGGHFIECGHAEC0A?D@GAC@AHCCI@?HFDAB@DFDBDIHDHA?AFIGDECAID@BABEIFBGBBFCGAHFGHHD@CA
@>chr21:9692338-9692458-5
GCGGCGTACTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCTCATATGACACTGCGGGCTTCTTGGGTGCAAAGAGGCAGACCACAGGCCATCTTCAGTA
+
BGH@@F@IAFHEDFAGCHEB?FIED@GCI@@@BCII@FF?C?AC?BCB?IABC@FAFDBFEA@HHGBEGGACHEAADDDACAGDI?AFBGCEIFC@CC1@
@>chr21:9692338-9692458-0
TCAGACGGTAATNTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCAACCAAGAAGCCCGCAGTGTCATATGAG
+
CAGBE@BE?F?G>DDCH@H@D?@GBHAI?BFHFB@?DIHHC?EAAAG@DFEH@H@DDBFABEHD?EFGGEH@DI@AHCCGH@AG@G@AFBHGGIGCCAAD
@>chr21:9692338-9692458-1
TCAGACGGTAATCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTAAAGATGGCCTGTGGTCTGCCTCTTTGCACCCAAGAAGCCCGCAGTGTCATATGAG
+
D?FABEIBBDC@BIIHFAGE@CA?IGCEDH@GDH@GDI@DACCE)IDECBAGDE?A@B@FA@AGDIHDG@?HICGFHCHACE@BD@BDGC?EGFEB??ED
@>chr21:9692338-9692458-2
TCAGACGGTAATCTGCTTTCTGCACTTCAAAATAAAGGCCTCCTGAAGATGGCCTGTGGTCTGCCTCTTTGCACCCAAGAAGCCCGCAGTGTCATATGAG
+
E@IE?@BIHBEHB?CEIAGDF?FGG@A@@HBIHBFDDH@?HABBGAB@IDDEH?EDE@GCF$GBFDBEHA??ACDD@IACHGEGGGI@CHIIB?@A?CGA
@>chr21:9692338-9692458-3
TCAGACGCTAATCTGCCTTGGGGGCTCCNGTCCATGCCTCAGGGCTCATATGACACTGCGGCCTTCTTGGGTGCAAAGAGGCAGACCACAGGCCATCTTC
+
GDHHICH>DIGBBDICB?DCC@A?ABD?0DAAGGBDDGIGB?GFGFC@GHFEEBGHFBG@D4@DBF?FFC@BFHED?H?IDBD@FFBH?@@AABHHI??F
@>chr21:9692338-9692458-4
TCAGACGGTAATCTGACTTGGGGGCTCCAGTCCATGCCTCATGGCTCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTC
+
DGBDGABCA@@A?ED7BEED?C?A?B?I?AEC@@CD?IFDI'HEBAAD?IAH@A?IH?ID@CFCEDE@C?HEBDC@DGG?HEHBIEFHBFEBFH@II?F@
@>chr21:9692338-9692458-5
TCAGACGGTAATCTGCCTTGGGGGCTCCAGTCCATGCCTCAGGGCNCATATGACACTGCGGGCTTCTTGGTTGCAAAGAGGCAGACCACAGGCCATCTTC
+
BFADF@CIBHAIABIBDDEBI?FGFBFGGD@?GEBFHEHFA@IAA&GEGD?BA@BD?CCBCG?BGIAB@DCH?@IHFEBCCH@C@@IHIAIB?HGD?CFC
@>chr21:9702397-9702489-0
ACCACAATGTCTGCGGTTTTTTTTCTCCCCCCCAGGTGCCTCGCCTTCGCCTCATTGGCCTTCTGCCTGCTTGGGGGTACCACGANCAGGCCCGAGGCGC
+
E?CBC+@CEGAHEDEAIE@7BHFFBG?C.DCBCEECCG?CA?GF@BCI5GCDHHGGAHDIDB?B?GFDDFFH!?DE@EAEAE?HB4EBD@BHDDFHCHCH
@>chr21:9702397-9702489-1
ACCACTATGTCTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCACCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGCGC
+
GIEFIFBFIGEDBI@@BDA@?ACCAA??@FFG?F@EBEIGGDFFHBBIIAGCDDE?FGC@IE@H@FAHFF@GI@A?@FHHGDC?ICEDFBBCH?GDD@CG
@>chr21:9702397-9702489-2
ACAACTATGTCTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCACCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGCGC
+
?I;EACC@AFCAEDHDADCBIDFAA@@?AFEIFAIAEH??EC?G??I@BCG@@A?AD??CHEFIDBIBCA?@FECFAFDCCBCACCCCCAGEEFHCDCIF
@>chr21:9702397-9702489-3
ACCACTATGTCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAAGCCNATGAGGGGAAGGTGAGGCACCTGGGGCGGAGAAAACAAACCGC
+
HHAAG@EEICEIDCF@E?IEHFAECHFE@II?FCCGGFBFHDFH@CFBE?CA$FGF)CAB?@BA@AFHCB@CGHCI@G@EEHHE?@FEAGI@:FII@GAB
@>chr21:9702397-9702489-4
ACCACTATGTCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGAAAAAAAACCGC
+
CFGFF@DD@FDCFHD@D?GA@HACG?CHE@C@G@ADGAEICGIH?EDC@@@B@HAEBC?G?AH@H?EE?D@FDGGHD@I@ICAB@FDAGI?F@DEDGCGH
@>chr21:9702397-9702489-5
ACCACTATGTCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGAATAAAAACCCC
+
FAEGGB@?@G@CFCHDEGBCEIABHGEDBHFBEFFFIHFAE@AEA?E?DBD@AACIGFCGCAEBHDHAD@IGC?H@@HBEE@CB@@C?GE)ABGGCII0?
@>chr21:9702397-9702489-0
CTCATACCACGCTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCGCCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGCG
+
??DGGFBE)@AGDBFEABGGDHDEII?CDHIE?CCCHIFI?GBC@AEC?@?@CCDICHCBGDBB?@A@@BECF??E?EGFEIF@DDFF@FGCHGDFA@CF
@>chr21:9702397-9702489-1
CTCATACCACGCTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCGCCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGNGCAGGCCCGAGGCG
+
BBHAI?EECBE?@D?@B?FACA?DGD?A@@GCHB@EGE?/CEHDFGAHFCI@@H@AGIEDABB?FIAEHC?BF?G??FAAFBBF?*@CHH@DCIB@F?IE
@>chr21:9702397-9702489-2
CTCATACCACGCTGCGGTTTTTGTTCTCCGCCCCAGGTGCCTCGCCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGCG
+
HE@?AA@HFFGFCDC@DG@EEI4BDCDDHB?HGHHGHBI@FBHBHI@HIE?@AFEDD@BGGCH@?@CH?G?IFDG@HFA@?HADCA@G?IIBDIHG?EFC
@>chr21:9702397-9702489-3
CTCATACCACGCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCACTGAGGGGAAGGTGAGGCACCTGGGGCGGAGAAAAAAAACCG
+
DIABI@FACF?GDHA?DGCG@ED@@?BBHBAD?GEFFIB@GBFH@BAHIBDE?G??BE%E?GHDAHA@DI5EAD@BIGHHFFH@CAEIIAG@@HE?DBDI
@>chr21:9702397-9702489-4
CTCATACCACGCAGCGCCTCGGGCCTGCTAGTGGTACCCCAAAGCAGGCAGAATGCTAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGCACAAAAACCG
+
BDIIGDEHBDGHH?CBIG?IDIE@FHH?A3ED@DAFB?AF@GHECHFGGHHCD+A@(DIC@HGGBFDI?A@IAC@GFHDEIDFGFIB@F6A-DGDD?GDB
@>chr21:9702397-9702489-5
CTCATACCACGCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGAAAAAAAACCG
+
@HAFBEHIBIICE@GIE?GHG?DCFEFGE?H@AGDEDCEB?FCDD?HH?CDBG?DABI@CFBCHBAGAGAFCGDEACC@IEFC@EGD??ABD@CGEDH?C
@>chr21:9702397-9702489-0
GAAGGTCCTCTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCGCCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGCGCAGGCCCGAGGCGCT
+
BHHGBCIGAGA?AE@D?GEFC@CFE;HGD?HG@FC?GAICG?G?GEABGIHBBHHHBIHHAHBDGDCB@CEIGGFHCIHAIEF=AEGG@?ICBH?B?H@D
@>chr21:9702397-9702489-1
GAAGGTCCTCTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCGCCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCNAGGCGCT
+
BFFGH@G?EFDBDBFBCCCC?B?HFCAAH@FIE?CFAADHFIA@HGFDF@AGECIEAIDFDHEDB@IGGC@HFEH?DE??CEDFAECFA@FB$FEFB?CE
@>chr21:9702397-9702489-2
GAAGGTACTCTGCGGTTTTTTTTCTACGCCCTAGGTGCCTCGCCTTCCCATCATTGGCCTTCTTCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGCGCT
+
@IEGI@5?CDCACBCDBAHACHI@@)BI@GI4AAB?FHAEGGCGDACHE.GH??C@HHEEA@B'GA?ED?F?CF?B@@BFF@EBGAFGIADEF?@IACCF
@>chr21:9702397-9702489-3
GAAGGTCCTCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCAATGAGGCGAAGGCGAGGCACCTGGGGCGGAGAAAAAAAACCGCA
+
EDIII?I??AAI?HBDAAA@IA@GG?GBIDH??@GCBE?HAGG@CFACCFH@?BIHCIHCDD:GG?HI?HB@??FIAGDBFD?EDABBDI?DFEDCIEBF
@>chr21:9702397-9702489-4
GAAGGTCCTCAGCGCCTCCGGCCTGCTCGTGGTACCCCAAAGCAGACAGAAGGCCAATGAGGGGAAGGCCAGGCACCTGGGGCGGAGAAAAAAAACCGCA
+
BBIH@G@EIHCH@@DDBB*CFFEGFG?GHCEH@CDCIAFFEBE@?"FH@EI??ACEIABEGCDIFEIHG*HAEDHH??AHAAAGCAGAFBAHDGAGAHF?
@>chr21:9702397-9702489-5
GAAGGTCCTCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGGAGGCAGAAGGCCAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGAAAAAAAACTGCA
+
@G?FGED?EE?G@C??DBEBBDFFF?FDCIGDDHIE?FI@AI!CDF?EG?@?@IFCHEBFGEEGAGGBDAHAGFBHE@G?B@@AHDA@A@DBIBCI%??H
@>chr21:9702397-9702489-0
GCGGCGTACTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCACCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGCGCTG
+
BBBIBAIE?AGCDGEE@@FDEA@GADG?GHHIFDFAGCHBHCG?FBFDIDGCDBGGIHFICHCF@HIFEG?@BDBBH?CIB?CAFDCIB?HHGIACC@EB
@>chr21:9702397-9702489-1
GCGGCGTACTGCGGTTTTTTTTCTCCGCGCCAGGTGCCTCACCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGCGCTG
+
DIBABDFICIHFGABIHBE@GCFGDE?H>D?AA@?I@BFGB@FEGIEID@?DFEE@A@H?EADGDABCBFBI@ICHAC@IGGBGCEGCFG?@GCHDGFG?
@>chr21:9702397-9702489-2
GCGGCGTACTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCACCTTCCCCTCATTGGCCTTCTGCTTGCTTTGGGGTACCACGAGCAGGCCCGAGGCGCTG
+
@CCFGCEDDE@AHGIECCD@?@HGFGF?DBAH?AGA??GBEFHI@HAHFBFHECFCF?@F@HBC0GAHBD@ADH@FIGADCDEF@@HGIACGAEADGEIF
@>chr21:9702397-9702489-3
GCGGCGTACAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGGCAATGAGGGGAAGGTGAGGCACCTGGGGCGGAGAAAAAAAACCGCAG
+
CBIF@IC@GDB?AI@CDDH@??E?EA@HBFEB?EAIFCAGCEGII@BE?BBH,C?F?HBDHIEA@GGHIGBIIEHDACAFDFCII@DHB@ADDG?D?DHI
@>chr21:9702397-9702489-4
GCGGCGTACAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCAATGAGGCGAAGGTGAGGCACCTGGGGCGGAGAAAAAAAACCGCAG
+
CBG?DGI@E?I?@H?IFFIGBIFEFB@EFDG???AHD@EFFAGCE@DA@@HA?AF@E?CD?=@?BDDA@GHB?BB@IDHDD*E?EHB?GGFCEIG@ECFA
@>chr21:9702397-9702489-5
GCGGCGTACAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCAATGAGGGGAAGGTGAGGCACCTGGGGCGGAGAAAAAAAACCGCAG
+
CABGF?E?CG?@DDIBFDI@CCFGHF??@??@DFHFFI?ACHHDFDDAFICICGGAHEHGEIAE?GDECAHAFDFCEIDDDF?GI@CGAEAB?CIBD@??
@>chr21:9702397-9702489-0
TCAGACGTTAATCTGCGGTTTTTTTTCTCCGCCCCAGGTGCCTCGCCTTCGCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGC
+
CEAGGFA1DBGI?GHFIEEB?D@D?IG?EGAHBGID@CFBEGCCBGHEFA=EAB?C@BHFEH??AFDCD@BF@D@IEHA?BGAD?GB@CBEC@CGGBA??
@>chr21:9702397-9702489-1
TCAGACGGTAATCTGCGGTTTTTNTTCTCCGCCCCAGGTGCCTCGCCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGGCCCGAGGC
+
C?DF?FF?CCD?ECECFCBDAA@;G?IDDHCFEIDABCEGDEBAGHG?FFFCAE@@CIE@BC@C@FGEDIDEIEH?HICCCCHBGEBGEEICA@IIF??F
@>chr21:9702397-9702489-2
TCAGACGGTAATCTGCGGTTTTTTTTCTCCGCCCCAGGTNCCTCGCCTTCCCCTCATTGGCCTTCTGCCTGCTTTGGGGTACCACGAGCAGACCCGAGGC
+
D?CADHFC?GGGEC?AHIGFG?IHAFE@@AIEHCFAGAI1H?EFBIEFBFAF@CDI6?FAHEIFACIABEFGE?F?GFBDAEF-IAC?H?C-?IBA?H?D
@>chr21:9702397-9702489-3
TCAGACGGTAATCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCANGCAGAAGGCCAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGAAAAAAAACC
+
HGBEFDEDCBBE@?D@IDDG0FD??IC?CBCFEIB@@BIGEFDHD@@.C@IFAIBIG?FABFB?CGCFAHB?II?D@EDGFCDCIBFEEDB@IEA@IH@A
@>chr21:9702397-9702489-4
TCAGACGAGAATCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAAAAGGCCAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGAAAAAAAACC
+
A@GH@GC"0??FBI?ICHBBIBH@C@F@FDGEI?E@I@EBCFHE@?CH?@G4@E@EEB@BDHIHB@CFIHFBICGFE?GI@FDB?B@AFDEBHEBIAIBA
@>chr21:9702397-9702489-5
TCAGACGGTAATCAGCGCCTCGGGCCTGCTCGTGGTACCCCAAAGCAGGCAGAAGGCCAATGAGGGGAAGGCGAGGCACCTGGGGCGGAGAAAAAAAACC
+
EH@CC???BII@DA@IAFEGCDEGBHCBA@F@FBIFFHIGFH@??DEGI@?ACHIGD?GCDAFBE?GEIBBCA?E?AB@DCII?GBGDEGG?FGHCE?EE
@>chr21:9704388-9704537-0
ACCATTATGTCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGCAGGCGG
+
AIHI-?A@EEHGHHCF?ACDBDFF@D?BGHHIDAGHDHBBCDH@FEEFDICGF?C@FCCBHBDF@FABFE?I@E)AHFBDE@CG?DDBF?IGB1GDGEIH
@>chr21:9704388-9704537-1
ACCACTATGTCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCTTCTGCACAGACTTCAGAGATACAGCGAAGGCGG
+
IDDBFFICAAF@GEDHDD@?DHGHAIFCCIG@H?GHF?DHBIAEGGIHIDGIBA?CDC?@IBBCB@=IFDGB?D@BDBCDI7FCHGD@B@F@C?IDFDFB
@>chr21:9704388-9704537-2
ACCACTATGTCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCTAGGGGGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACTGGGAAGGCGG
+
ABHGDAG@GF@F@FAIAB@DIE@EICA?FCDHC@?BIAAA@?BB?A$DDGD2IF?BFEGD@A@CAIAEFDG?BCF@A?@@CAEH?@@CE3I.DIE?CHC?
@>chr21:9704388-9704537-3
ACCACTATGTCAGCTCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCTGNAGTCTGTGCA
+
I@CAB@EB?EIFIFDHEC???EI@HA@?GBEICCHDA@@GDDHHAEHDDEFACCHAE@?@EFH?EEFB?HFCDB@?IFBC@ADHDEAGB'IEIIDFDF?C
@>chr21:9704388-9704537-4
ACCACTATGTCAGCNCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCTGAAGTGTGTGCA
+
F@@F?B?AH?CHH@6EII?CC@ICFAF?B@C?AIFAAHHHECB@FHDIAII?IB?HIACA?@FFGIH?GF@CCBE?AFFIIDGHIIGH@D@?D*ADFBEB
@>chr21:9704388-9704537-5
ACCACTATGTCACCCCCGCCCTCGCAGTTCCCCCGGCCCGCCTGGGTCTATGCTGAGGAGAACAGTGCTCGGCCTTCGCTGTATCTCTNAAGTCTGTGCA
+
C?GFF@DGH?A?,?GHHEA??EIE?%DB1AEHDGE@HDHHFDHD@C@?I0DHAAAIHGA@H@H@/CFBAE'C?B?AHGDIEHIABFFI2AABA?ADFCCI
@>chr21:9704388-9704537-0
CTCATACCACGCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGCG
+
IEAH@EBAGHIIACH@@C@FGFB?CF@EF@@?BCE?EH@GI@AIAG@I@ID?BDDFDCFB?FCDGG?GHIII@GD?CF@FCF@GBCDBHCCC@ADA?BIB
@>chr21:9704388-9704537-1
CTCATACCACGCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATAGAGCGAAGGCG
+
EDG?DCEHD@H?EGIGAEEBEHBAHGGCECAFFEAHID??G@B@HDCFICC???CF@GBFA@EFIB?F?EI@@HF??@GIDBABC@?DH;ECDA@GGIHC
@>chr21:9704388-9704537-2
CTCATACCACGCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGCG
+
C?A@D?BAIACFGD?FB@IFIIAGHE@BH?FDDGCBIGH@CFCHDDEHEEIDEFE@EEACE@B?DFCE@EBBGFBD@D@HIC@HCCGHCABI@FIB@@EB
@>chr21:9704388-9704537-3
CTCATACCACGCAGCCCCGCCCTCGCGGTGCCCCCGGCCCGCTTGGGTCTGTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCTGAAGTCGGTGC
+
FA?DCHAFDEFDCAEHG@B?D@C@@BE?GI?CB?%GI?E@CB0D@CGDGHHACBHHIDAHGCIGAII?IIHD@@FAE?EBCCAHG?@?G?IHH?H>HBAI
@>chr21:9704388-9704537-4
CTCATACCACGCAGCCCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGGAGAGCACTGCTCCGCCTTCGCTGTATCTCTGAAGTCTGTGC
+
IEB5@BEAGFEHHDCG??I?ABEEGAF@B@D@GCBD@EGFDA)HHFCBFI?G@HCBGHD?CD+BAGEDF@HDCFF??GEE?@GII@ACBCGH?DHFCB?E
@>chr21:9704388-9704537-5
CTCATACCACGCAGCCCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGGAGAACACTGCTCCGCGTTCGCTGTATCTCTGAAGTCTGTGC
+
EGGBGDIG@H?HEHBEIGAFBGBAE?@CHD?BFABHEEGGCH@?BIBABGIHI@B@?HCIGA??BD@GCECC??,@EBF?IBIBAA@HBIB9CB?DCH?I
@>chr21:9704388-9704537-0
GAAGGTCCTCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGCGGA
+
DCAACAFI@I?EI@@BE?BIDEBEDBBGEEFAC?FF?BAB@?BGDBFDBE?@EAD?CDIE@FBC?FCAHFIE??IG@GIHCAHCF@FHDCCHFIIGAFD@
@>chr21:9704388-9704537-1
GAAGGTCCTCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGCGGA
+
@AEHEBAIBHBEHCFD?HHHFDDIGFGGFDFGHHF@EAAD?BD?GHBHEDE?EBDI@GCFIDHBDCIB?GFFCIGEEGCIDDAGBFF??BCABDCCFHGH
@>chr21:9704388-9704537-2
GAAGGTCCTCTCCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCNCCTCTGCACAGACTTCAGAGATACAGCGAAGGCGGA
+
CA@AHBIDEGG<IA@?BAG@DCICCIE@?H?A@B?ABG?GAC@I@EBIBDAGH@DGHIIAFCD"EEDD@CCCCHDCGAHDCCIEGCCFFCH@FD?BCHBH
@>chr21:9704388-9704537-3
GAAGGTCCTCAGCTCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGAAGAACACTGCTCCGCCTTCGCTGTATCTCTGAAGTCCGTGCAG
+
CI??DIH@CBGC?GHGGHEB@CIAEF?C@GHEIACABAHDHIFCEDD@HI?DHGF?1AAEBEFHIDCFD?BE?A@BHFH?DEFAAHD?EFBG?#?GBHCB
@>chr21:9704388-9704537-4
GAAGGTCCTCAGCTCCGCCCTCGCGGTGCCCCCGGCCTGCCTGGGTCTGTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCTGAAGTCTGTGCAG
+
CGAIEGECIH?@@DAGBECD@FCAECIBHFIBB@DIC1I?@I@F?CFIA?GAHCCDCI?HFGCFGF@DGAAH?G@@D?DB@DHB@FBB?CAD@DBCBGGE
@>chr21:9704388-9704537-5
NAAGGTCCTCACCTCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTNTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCTGAAGTCTGTGCAG
+
4GIH@D@HF?E:BF@HB?BEGGH@D@EAF?IHG?HG?IBGHE@?IC?C6EEIEFD@AIDD?GCCH@CEHHCAC?BF@GBHBDD@@GDI?DF@FDAEEFIF
@>chr21:9704388-9704537-0
GCGGCGTACGGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGTTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGCGGAG
+
IFHE?GEIH&BCDDGBH@E@EBFAC@BICIFGE@@HD@FHGDBAEA@BHC?HB@,B??EIHAA@?AAI?EDDH?DF?HIBHA@FE?CI?HEIIFFFEE@D
@>chr21:9704388-9704537-1
GCGGCGTACTGCGTTCTTCCCATCACACACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGCNGAG
+
AACIGDEAEHIBDHABFDE?GA8AF?E2FD@DGGCACEF@I?HF?DBDFGHCFFGDC@HBGI?EHBAHG?IIIAB?B??GECC?IBB?FF?@BHC@*FGE
@>chr21:9704388-9704537-2
GCGGCGTACTGCGCTCTTCNCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGCGGAG
+
DDFBE@CIB@?FC+@HE?F-D?@FCFHF??F@AE?CFC@BEIIEBAFHFBH?I@I@F@BCF8BGA?A?@B@H@GG@DBEDHBACH?HIIAEICCEFAII?
@>chr21:9704388-9704537-3
GCGGCGTACAGCTCAGCCCTCGCNGTGCCCCCGGGCCGCCTGGGTCTGTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCGGAAGTCTGTGCAGA
+
?I@I@@A@?FAGDI<ACDGAFC@7?IFHGCDADB$ICADGHG@EAA?GCFE?CBHIA?DHEBCEBEBHHDG?D?ADABBHC??IG%CGIC?GFFEFEFFG
@>chr21:9704388-9704537-4
GCGGCGTACAGCTCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCTGAAGTCTGTGCAGA
+
BHCHCIDHBBAE@BI?@BA@HEAH?H@?AHDE?EEHHGGCA@IHII?HEGHBHCG@GHHDCHFHG5@F@H@EH?AHEC@DCCBAEIFFF@BFIBFBEGBF
@>chr21:9704388-9704537-5
GCGGCGTACAGCTCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGNTCTGTGCTGCGGAGAACACTGCTCCGCCTTCGCTGTATCTCTNAAGTCTGTGCAGA
+
IBDABEBAB?FF@EBADD@ICABHAI?A?IHEIBGF?EG?BG?2@I?HID@H?9EC?GGG?EECHAEAD@@EF-EFG@HAECHDD?:EBEE@CBFBIIFF
@>chr21:9704388-9704537-0
TCAGACGGTAATCTGCGTTCTTCCCAGCACAGACAAGGGGAGCATCGCCAGGGCGNAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAGCGAAGGC
+
CBGBEFEE@AGH@HF1FAA@A@HAE@BFDDAFHF@?AF.A?AH??FDFI@DCEAB3?I?EECG?CFBFH@DABBGBFCHFFGA?ADFDAECGAHF?HABH
@>chr21:9704388-9704537-1
TCAGACNGTAATCTGCGTTCTTCCCAGCACAGCCAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCATAGATACAGCGAAGGC
+
GIEHFE8EIDACHIHBHIFC?HA@BFDFFHH@6EFDIIBBCBEHGGBAGCEFEHGBGFHGD@?CCD?GCIBICFDGF@3GFDHE;AAF@HHEAGDGIEAF
@>chr21:9704388-9704537-2
TCAGACGGTAATCTGCGTTCTTCCCAGCACAGACAAGGAGAGCATCGCCAGGGCGGAGCTGAGTTCTCCTCTGCACAGACTTCAGAGATACAACGAAGGC
+
AICICDHEB??DDEBHAFFGBDBDDBIBE@FDDCGFDGFCCGHA@HCA@BEB??G@FEHAFIF?BFHAGFBIH8DAGDDAEDB@EFECGACE(HGIB@H?
@>chr21:9704388-9704537-3
TCAGACGGTAATCAGCTNCGCCCTCGCGGTGACCCCGGCCCGCCTGGGTCTGTGCTGAAGAGAACACTGCTCCGCCTTCGCTNTATCTCTGAAGTCTGTG
+
ID@HDGF?BAEHECIGD=HHEH?GGFEA@IF3BDFEIDHI?D?IGEFD??FGAIAA?E)C?IHGI@HF?H@@@HHHGFGIBG;ECB@DHAGBIGIG@CB?
@>chr21:9704388-9704537-4
NCAGACGGTAATCAGCCCCNCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGGAGAACACTGCTCCGCCTTCGCTGTATCTCTGAAGTCTGTG
+
:?DABBCHBHCAGFACD??$AIECGDDDIICHIHE@AB@HD@?HD@FGBAG?FBFDID?@DABC@??@@?D?CBC?GIFCB??BGBEBG?@@EFIEIBFA
@>chr21:9704388-9704537-5
TCAGACGGTAATCAGCCCCGCCCTCGCGGTGCCCCCGGCCCGCCTGGGTCTGTGCTGAGGAGAACACTGCTNCGCCTTCGCTGTATCTCTGAAGTATGTG
+
HDEHFDAEHGCDB@BAD@?I?FIEGI@IDEE?FD?EIHI@AH@I?C@ABE@IDIIAFFD@GFFDHBD?@??)D?IBAGBCFGHGFHAE@IDFFHB2IF@H
@>chr21:9704580-9704675-0
ACCACTATGTCAGCGCTCTCCTCAGCACAGACCTTTGGGGCATTGCCTCGCTTTGGGAAAACTCGGGACCGCATAGACGGTGAATAAAATCCTTCCCTTT
+
AG@HA@ABECD@CGG+?EFGGH@CIAGF@?@?BCBFBEAGCB%IGBIF??CAH@DBEH0BD?DF?EDCD@EGEDCEFI@?H?F@ID?IDGBHI@B@BI?G
@>chr21:9704580-9704675-1
ACCACTATGTCAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACGGTGAATAAAATCCTTCCCTTC
+
EHE?CBCAF@AE?IACCFCDDHDB??DGCH@AECFHIFB?BDE@DDFEIEB@?AH@AGCDCBDDII@AGGIEECHIAIH?FH@EB@I@?FGGDH@@AII5
@>chr21:9704580-9704675-2
ACCACTATGTCAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACGGTGAATAAAATCCTTCCCTTT
+
?@FAEIIFCHGGA?@FDFDBBDHDHHBEGEGABGI@ABH@CDHB???HAC?GGEGHFHCC@I@I??A.FECG@GHIFBEGA?D@A@CHAGDBG?AAD?EE
@>chr21:9704580-9704675-3
ACCACTATGTCTGCAGAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCCAGGCAGTGCCCCAAAGCTNTGTGCTGAGGAGAA
+
DB?DF?IHEB@EGE?(HCBIGAIGBBAFCDDG?DDHE@@9IBAAAFAFAHHFID?D?DEEAII?HC&A?BA@HDDHFCCHFAB:F:@?HFCBH@?@HIB-
@>chr21:9704580-9704675-4
ACCACTATGTCTGCAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCTAAGCNAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGAA
+
?E?CGDIAICBGAIAHHHAGHHDIIHF?EFDHI%@FFAIAFAF?FIBE@HBEAHCCBCDE@4CIEC.?FFHHGCAFAAEEIEBIE@IFFFECHD@HAG?D
@>chr21:9704580-9704675-5
ACCACTATGTCTGCAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGAA
+
EBE@@DIDD?HFBBGAAEEAEBCGGAGG@FC@GI?EEA@G@@BDGE,?CD@DCACGC?ICFDDDEHIHGH@CD@HFHDGIEH?AGIHF??GFFFFCIA@B
@>chr21:9704580-9704675-0
CTCATACCACGCAGCGTTCTCGTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACAGTGAATAAAATCCTTCCCTT
+
G@FHDHDEBHFFFAFHDGH@E3HIBFH@D@FCCEGFAC@DFF?HIDEBGIDBBBE@EA@@DDB@DGDG@IGFCHA@GHD9AA?C?&@D@@GHF?HFFFGG
@>chr21:9704580-9704675-1
CTCATACCACGCAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCATTGGGACAACTCGGGACCGCATAGACGGTGAACAAAATCCTTCCCTT
+
GDGDGA?ABBF?D?IBFBEBGH?CBAG?H@?CEA?@EGDIAAAEAB?AAACH2EEFE?@D@AI@EAIFCAHAG@??@?HGDDB@F!?@ID@EIFGG@GIH
@>chr21:9704580-9704675-2
CTCAAACCACGCAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCCCTTTGGGACAACTCGGGACCGCATAGACGGTGACTAAAATCCTTCCCTT
+
AIII=G?C@AGC@BGEEGDA?FCAHHACI@HIH?ED?CA@BGGF@IIGB?+7?EHGHEH?CBAGH?E?IEGI@HIDE?HCBA0F0?GIECDAC?@HHH?@
@>chr21:9704580-9704675-3
CTCATACCACGCTGCAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGA
+
BDFEB@BAGA<GCG@GEIED?HFEAFGD@EA@B@AEAFB@BAEBBBECD?GG?E?BADHFC@GIFCAEGBFDEEHE@@EEH@DEI@CEBG??IHABAFCC
@>chr21:9704580-9704675-4
CTCATACCACGCTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGA
+
DGEGGC?BB?CHE?@G@@BA?DEIEIE?F@@HDFGHCHC@C??FBIIH?G?IFC?F?AIB3IDDGBCFEFHDGEHGAD@DAGA?FDE@HCCAD??DGH?A
@>chr21:9704580-9704675-5
CTCATACCACGCGGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGA
+
DI@D?EFCHB?B8D@CDDCFGCDDEDGF@EEH@E??IEEIEACHCDF@BGIFE?G??EI@BBHIEIE@EDF@%GCEDBHEI"ACDIIABFBFGGCFGCBC
@>chr21:9704580-9704675-0
GAAGGTCCTCAACGTTCTCCTCAGCACAGACCTTTNGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACGGTGAATAAAATCCTTCCCTTTT
+
CDBBBEDIIGE8?G@CD?@BDFBHA@IEFFHFECC:AEA?CEAAGGBA??@GDHHEIBBFEDC@@HGBIEG@BADBB@D@EBH@EBHGFAFA?HADAEIC
@>chr21:9704580-9704675-1
GAAGGNCCTCAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCTATGGGACAACTCGGGACCGCATAGACGGTGAATAAAATCCTTCCCTTTT
+
CIBFE!?FBFBGGA@AIGGABEGCBHHDAF???AHFB@BEAA@DIFHDD@I+?ECDAIFFIDBC?BBEDABIA?HHAFGBGCEHDIHDG?IHF@ECIB?B
@>chr21:9704580-9704675-2
GAAGGTCCTCAGGGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATCGACGGTGAATAAAATCCTTCCCTTTT
+
B?IA@GFIDIGF8CBIDBED?FEFEBEIG?@IB?E@I@??I@GC@HFCHF?BDAH@FCEIIA?DHCFGBF@HD2?HDED@ECG@HICBA,HI@CBADDF?
@>chr21:9704580-9704675-3
GAAGGTCCTCTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGAAGAAC
+
HHAIECHB?ACD@HCAEEC@CEFGE?DA?HBHDHBHHFH@BDGCIF@DEDFFHDFBFI?DI?F@EBGHE@CEFDIADDHAFAIIC?BFCBEA?G7@I@E?
@>chr21:9704580-9704675-4
GAAGGTCCTCTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGTAGTGCCCCAAAGGTCTGTGCTGAGGAGAAC
+
@HEHFDACHICGEIAFC@DDFHGEEGCFGBHF?E@GGAD@HHGHBDIFEFGGF@H?AIG?AIBFAEFDD(H??CGA?DBH@GC@ABF?GHFB?AC??DBH
@>chr21:9704580-9704675-5
GAAGATCCTCTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCANAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGAAC
+
FIDA*@EEB??D@?IEGDDE?H@CFFFHHBHAFID@@H@@ACG@?HAHD??@BI@HABIE?,?IHDDFIA?EAGAFAFFGGIFCFA??GGAHE?BHG@HC
@>chr21:9704580-9704675-0
GCGGCGTACAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGNCTCGCTTTGGGACAACTCGGGACCGCATAGACGGTGAATAAAATCCTTCCCTTTTC
+
B?FFGAFEDGCBDDIHE?BFGHB?DGDCBBC?FCC@GHEFGFE6BDDEDF@EFBEAABGCIICG@I@?CIFDEABBH@@BCEBDBC@BGGA<D?GDHCI@
@>chr21:9704580-9704675-1
GCGGCGTACAGCGTTCACCTCAGCACAGGCCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACGGTGAAAAAAATCCTTCCCTTTTG
+
AFDEAACH@DG?AF?I/IIEFFB@I*AI;IB@I@GAI@F??@FBCEBAII?ADDBIGIGH?FGF'AD@ICDIFAE@H??A@?8GEDEHI@FDBAG@??A?
@>chr21:9704580-9704675-2
GCGGCGTACAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGAAAACTCGGGACCGCATAGACGGTGAATAAAATCCTTNCCTTTTG
+
H?@G@IEEIBHCGADDB@?A?ADCBBCFCGF?CC@DDGEIGE@?CBBHBIHAF?G?9CB@BECBEIAHF?CAH@CAGIBBACBD@IDAHH?I:H?FC?EC
@>chr21:9704580-9704675-3
GCGGCGTACTGCAAAAGGGAANGATTTTATTCACCGTCTATNCGGTCCCGAGTTGTCCCACAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGAACG
+
ABFBI@EEFCCBDG?DEFF@G7DECGDECG??EFDAFIGGB&?HBDHDAAEBDDIHIB@A.IHHHGF@ADEDGAGFIHHDII?AH@I@?E?FCGA@IA@C
@>chr21:9704580-9704675-4
GCGGCGTACTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGAACG
+
GBADEDEIDIH?G@CIIIBFICBEECHFFCIIGB?H@AIGHACDHIGIADAHFF?B?HEFI@IAECEBI?ECDAAICHB?A@DIII?ADGBBIIB@GGGB
@>chr21:9704580-9704675-5
GCGGCGTACTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAGAACG
+
B@GH?BGABFGDIH@EFGBGAFABHIF?IGFFF@IACEHCCCD?BHCAFBHDC@FFAA@FHAEDHHIIGC?DFBGIHBCCB@BIHHAHICHCGCDCAEIB
@>chr21:9704580-9704675-0
TCAGACCGTAATCAGCGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACGTTGAATAAAATCCTTCCCT
+
C??BD@;ACHAICBAB@CFFFII?DE@D@EAIHACAF?C?GCEBAGF@EIFEI?GIHEAE?BIHGHDGH??G?DBACHBAH+GGC?AEBD?DHFCE@DE,
@>chr21:9704580-9704675-1
TCAGACGGTAATCAGCGTTCTACTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACGGTGAATAACATCCTTCCCT
+
H@GACF?AGFHCFBCB??FFF0AF@AIB@E@ICCDCCC??DC?GGI?G@EACBGG@GHIGE?AFCGHFBBBCHDCDEGCIBG@@HBEDE'EBGF@IHGDE
@>chr21:9704580-9704675-2
TCAGACGGTAATCAACGTTCTCCTCAGCACAGACCTTTGGGGCACTGCCTCGCTTTGGGACAACTCGGGACCGCATAGACGGTGAATAAAATCCTTCACT
+
HG????CGDCAIB@2@FBGBC?AIHFHD@ADDD?AIDICDEGH@BGDFBG?BEBAIAGH?D?II@GAGBB@D@GAC?GIGGHHHG?AIICH?BGBG@2EA
@>chr21:9704580-9704675-3
TCAGACGGTAATCTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCGATTTGTCCCAANGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAG
+
A@F?ACH#E@GCD@?BIADFHHB@HFBECH@DFI?H?CFI@F@FBBBBFHEDCE?%IEI@FGABF#D"DC?CB@EABAHBFCFFGIEC@CBEGDHFFGEG
@>chr21:9704580-9704675-4
TCAGACGGTAATCTGGAAAAGGGAAGGATTTTATTCACCGTCTATGCGGTCCCCAGTTGTCCTAAAGCGAGGCAGTGCCCCAAAGGTCTGTGCTGAGGAG
+
FEBAE?EH?FDCB@ECDH@IAEH?AHIE?GDFDBCBFABAGHIIF?@FICFE@+E?@BIFDF!DBD@@BCBGEDA@@FCBBCGI?@DECA@HGGFDEFDF
@>chr21:9704580-9704675-5
TCAGACGGTAATCTGGAAAAGGGAAGGATTTTGTTCACCGTCTATGNGGTCCCGAGTTGTCCCAAAGCGCGGCAGTGCCCCAAAGGTCTGTGCTGAGGAG
+
AGBDAHI@CDCBEIDGGFE?F?AIGDD??@EG'FIGAHHF@@@IHF3ICF?@A@GBDCDGCEIFAI@!F8GIFD@?FGHH@AE@BBG@HHAIGGGH?GHA
@>chr21:9704672-9704787-0
ACCACTATGTCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGTAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCGAG
+
CDDDH@IEFGHHID@?FCDAEH?CEIAAGADGIEGACDBCD"BGBACA@FA?AEE?IA3@FG?DCEG@CAHAAFHDFCGFGE@EGD@D?HDA?D?B?EDH
@>chr21:9704672-9704787-1
ACCACTATGTCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCGAG
+
GBEEGFCBBHDBBBFHIABAIGEEBD@DBGHHC?EGD?GGBBDA?EDBFE@@B@IB@AGGHID@G?FC@GDGDGDEFBBIIEHA@I@CBB?D@?DAEB?@
@>chr21:9704672-9704787-2
ACCACTATGACAGCCCTGAATAATNAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCGAG
+
AFFFAD?HE2B@I?EDAED@BDDB)@AHB@@EDIABA?CAFA?CBFCABI?A@CHGFCHG?HGHG@@A@HE?FBGAAGGIFADBA?CHBEIA@HFBBCBI
@>chr21:9704672-9704787-3
ATCACTATGTCTGCCTTGGCTTGGCTGGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTATCCACACTGAGCCCTTCTAACTGGT
+
I(@EAGG@@FIDACGA@HGIBII?I@?BE?CICBCBGFIAFBBAHBDFDDIDCCF?GAB?@?CAGEA@GGB@@D;DABFE?HIAHFIHEIDIBGAAA@IB
@>chr21:9704672-9704787-4
ACCACTATGTCTGCCTTGGCTTGGCTTGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTAGTTTCCCTTTTCCACACTGAGCCCTTCTAACTGGT
+
IGEC@I@CF@DCIECHBC?HCIICF?ICFEBFI?HH?@IAFIEFIBADDCE@EA?DDBFADHHH9IHB@BHF?9II@FBCAIBBE@IGEEEI?BG?E@DI
@>chr21:9704672-9704787-5
ACGACTATGTCTGCCTTGGCTTGGCTTGGGAGAACCTCGGTTGGCAGGATTCAGAGCGGCTTTTGGTTTCCCTTTTGCACGCTGAGCCCTTCTAACTGGT
+
@?4H@DBHBIFG?IDIH@@?CDAAGGAF?&CCAIEIEBCD@EH?E@@GFFFDB@CI>@FID@IDGFC?GCDCFCDH(ADH1@HCB?EB?FEAAECHGBBF
@>chr21:9704672-9704787-0
CTCATACCACGCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCTCCTCTGAATCCTGCCAACCGA
+
?IAFAF@IBHAB@AG?EC??EHBEHFB@FIHCBAAIBIDIE?FIIDDGD@FDBCAF?BHIBA?BCACCGBCBBIDEBD>GEIH@?@HBGDB@?HCCBEC;
@>chr21:9704672-9704787-1
CTCATACCACGCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAATGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCGA
+
I@I?G?FGHBEI?HAFAEEBC?ADCEDEABEEEFGHF?IBC?BCIA@FGFF?CH0@?BHH@IDBA@HCEAGHGI@CH?BEEDFAB?ADG@DCBEBBDHE?
@>chr21:9704672-9704787-2
CTCATACCACGCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCGA
+
DA?HGB@BCIFB?FCEEHCD!A?FDCF@GCIAEHIH@EEGCFHBHI?DGAGIDHEI?D@@F@IIE?EEFDC?IBADGFEI@@GC@?FBFCG???HCFBBC
@>chr21:9704672-9704787-3
CTCATACCACGCTGCCTTGGCTTGGCTGGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGNTTTCCCTTTTCCACACTGAGCCCTTCTAACTGG
+
AHGAFEEDD?HHIE@BBEBE?FDGIE@@H@C@IIGDC?BGBHDGECBCABFB@IDDCHCADDIFEE8DEAH??IIHIB?AIFGGHAD@CDAADC?GEB@E
@>chr21:9704672-9704787-4
CTCATACCACGCTGCCTTGGCTTGGCTTGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCCACACTGAGCCCTTCTAACTGG
+
@GFIHBBBEHB@E@GGBGICF@AIAIEE?IB@CAC??C??CCCFECHCFCICCCF@CDHDEAGFCBIHDFCH?BGHDDDBDC4GHF?CBFA?I@BIBG?F
@>chr21:9704672-9704787-5
CTCATACCACGNTGCCTTGGCTTGGCTTGGGAGCACCTCGGTTGGCAGGTTTCAGAGGGGCTTTTGGTTTCACTTTTCCACACTGAGCCCTTCTAACTGG
+
ACC??@CEIH@3AE?AFGH@CFBCI@A@BE?GA,IGEA?GG??H0H?E@$IFBCFHACIIIHIBHF?FHCG!EAGH@IFB@@@@FGFAHIIBCAFHEFHF
@>chr21:9704672-9704787-0
GAAGGTCCTCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAACAGCCCCTCTGAATCCTGCCAACCGAGG
+
EBEDD@ICHH.BICIBIIEGFI@ACDEECF?IC@EDHHF@A?BFEDH?GAA?EF@GBACIBFBFIBFFCBIG$AI@FBHA?FH?FI@BBAICH?GF?FA?
@>chr21:9704672-9704787-1
GAAGGTCCTCAGCCCTGAATAANCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCGAGG
+
CBFIHD@EBFIBADEB??EDFA"BA@E@AGAEFDAGC@CAGAEEA?AAGDA@A@BGCEDBC@IGG?GHCBD@A?DHD?G?B@DBGFGDCGDECDH?EAH?
@>chr21:9704672-9704787-2
GAAGGTCCTCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAANGCCCCTCTGAATCCTGCCAACCGAGG
+
@CBEFCGDAGFHD@DID@AGBBHG?FAB@CBAACG@?ICGHFDCBI?BD??@@HFDD?E??ECD?GF@@A@BC>B@B?ED?EEBEFBG?I@BGBCEGC@C
@>chr21:9704672-9704787-3
GAAGGTCCTCTGCCTTGGCTTGGCTGGGGAGTACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCCACACTGATCCCTTCTAACTGGTC
+
DD?FE?HAAFCG@EHFDIIAEBA@@?C?GDI=@DG?B@ABBECFHIBB?ECE@FDFHF@H???FHDHAF?BA?CCEGA?AIEDB*FEEBC@DIHFBIDGH
@>chr21:9704672-9704787-4
GAAGGTCCTCTGCCTTGGCTTGGCTTGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGCTTCCCCTTTTCCACATTNAGCCCTTCTAACTGGTC
+
HECACAB?E?IHBCFFHHA?DB@CIFBD?I?G?@AFGB?DBCI?AD?F?BFCBE?EIG@HHG@C3?B3DCFIEBDG@EBF!B5FHAAA@CD@I@A@FGE@
@>chr21:9704672-9704787-5
GATGGTCCTCTGCCTTGGCTTGGCTTGGGAGAACCTCGGTTCGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCCACACTGAGCCCTTCTAACAGGTC
+
HD7AHBCHDGABGIHACCBGA?@FI0F@?IAII@CIGDDCI!CCBDC@IBBCE?AFG?HAG?GCBE?AGG@BGD?@EEFHA@AGBIGH?ICGHBB$GEHH
@>chr21:9704672-9704787-0
GCGGCGTACAGCCNTGAATAATCAGGGTCAGAGNCCAGTTAGAAGTGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCGAGGT
+
GHDC?CE@EBEEC,?BID@BIG?CIIBGAIIB@/CEAADCEEEH@2HFI@BGFG?B?BGIFFEE?HD@AGEIAA??DE@CDEHC?E@AAICEEHIGGA@@
@>chr21:9704672-9704787-1
GCGGCGTACAGCCCTGAATAATCAGGGTCAGAGACGAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAAGCGAGGT
+
AAAGIIHD?I?GHEEEIDAF@BDIDEHHEE@CBFD%FF?BB?GHIIC?EEC@?HD@?AEEHBF?IHG?AIDHBEBE?HBIBE??AHH?EDIGH>C??GFD
@>chr21:9704672-9704787-2
GCGGCGTACAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGTGCTCAGTGTGGAAAAGGGAAACCNAAAGCCCCTCTTAATCCTGCCAACCGAGAT
+
AH?B@DDHFCDEHHIAIB@GAEBIIDBFFDBDCBDFB@BH?H?B@,DFFHBDFAA??G@EG??ECEEIA7A@HHI??CIHG9C?ABBDH@9H?GEBB?(?
@>chr21:9704672-9704787-3
GCGGCGTACTGCCTTGGCTTGGCTGGGGAGAACCTCGGNTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCCACACTGAGCCCTTCTAACTGGTCT
+
CCHA?C@D?@?DGIBGIFBEBBFBHADIDICACB?DAF0DGE@A?HFE?@DDFC?ID?C@AADIFGCBH@GCEEDADF@HEADA?C?H@DDHHBI@E@IF
@>chr21:9704672-9704787-4
GCGGCGTACTGCCTTGGCTTGGCTTGGGAGAACCTTGGTTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCCACACTGAGCCCTTCTAACTGNTCT
+
AAA?IIAEGEFICICABD@CAF?EAA?FDA?HHHI4EEA@EHGDE?CBCAAEGEG@CACEH@B?DDGACIHBGF?/IB?IFG@BACEBAHHGFBCG=FG@
@>chr21:9704672-9704787-5
GCGGCGTACTGCCTTGGCTTGGCTTGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCCACACTGAGCCCTTCTAACTGGTCT
+
HBEADAH?GGHA@I@IHDF@@CAEIGGFCEI@B?GCDG@B@EBCIDCHICFAED@FGCDI@EG?FFAIACEABAEADIAFGC?GHBIFI@ED?HAF?CFA
@>chr21:9704672-9704787-0
TCAGACGGTAATCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCG
+
??BHA?HA@A@HCHHF?CEBADFADFE?HGABC@@DDCGBCIF?EHG?BCABD@GCBF?GECHI@CDCGACGEBBEFB@CHG??ADFIEEC?@DEHDEFA
@>chr21:9704672-9704787-1
TCAGACGGTAATCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCG
+
DCBFEA?EFA@AECAHBFFB?FICFABAEBHDIC@CH@DBCDHC?BDGGA@BFIFC?HB@?EIBE?BAFGHCD?@HFCCBCDGFA?BDAEI?C?BFADGC
@>chr21:9704672-9704787-2
TCAGACGGTAATCAGCCCTGAATAATCAGGGTCAGAGACCAGTTAGAAGGGCTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTGCCAACCG
+
GIA?DFDAE?FHABFEBHIDHDGIHE@H@@FHE?HCAGDHF@AFIDDFICDC??@?AAIHCCBDBHC?FAHDHF?IH????B@AGIAEA?EHAIGABADB
@>chr21:9704672-9704787-3
TCAGACGGTAATCTGCCTTGGCTTGGCTGGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTATCCACACTGAGCCCTTCTAACTG
+
BFGEHCHAFFICIICBBA@HEAB?@?D?EDFBHDBG@F?C@HEC@EEE@BDBH@DCCAG@@IAACI@G?DE?DCBH$FCBH?HF@DIEAC?G?BA?GI@?
@>chr21:9704672-9704787-4
TCAGACGGTAATCTGCCTTGGCTTGGCAGGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCCACACTGANCCCTTCTAACTG
+
HICAAA?FEBGCG?BGAIAACDCI?DG8DHBIE?@ECEAHDE?GFA@BHHIBDIA?I@G@BBAEIBC@AI@"C?@GE?HGAEIGECC6@ID?C@BICECF
@>chr21:9704672-9704787-5
TCAGACGGTAATCTGCCTTGGCTTGGCTGGGGAGAACCTCGGTTGGCAGGATTCAGAGGGGATTTTGGTTTCCCCTTTCCACACTGAGCCCTTCTAACTG
+
GCAIHHHDIB@?CFFH@C@ABDCHBDGDDBFIGGH?B?BICIABD@G?BIEDIBH@EAFHI5GBCBB?DCDFBI,@AIEIHEBGFDEG@ACCHFDCDFE?
@>chr21:9704828-9704956-0
ACCACTATGTCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTATAATGCTAATGCACTGCCTCAAT
+
D?FAHC?FFBHAII?@ICDBB?IBFHF?EGBI@@DB?G@EEFIBGGHECBH@IGGGEBDHG@@EEFIIDAIF??CG/DF?CAFDGIDFCG@BBEBFGF?E
@>chr21:9704828-9704956-1
ACCACTATGTCAGCATCCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAANAAGCNCCTGTAATGCTAATGCACTGCCTCAAT
+
GGDCDEIG@FFGDDE?<H?DE@HF@FFIBID?AEG?DADIEBEDCBCC?ADAA@DGHBCFG@DHDAD'C?FF8ABBCGDBCCDECEFHI@IG?CBIEBBB
@>chr21:9704828-9704956-2
ACCACTATGTCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAAG
+
EIICEDI@ECBH@GB@HIFA?AHABIHBDDEHGIIICBECF?AH@?AIHDHHF?@IC?@E@CEAFDIECADFHAEG@AFIDIIADBBAG@CEH@ICC?H:
@>chr21:9704828-9704956-3
ACNACTATGTCAGCAAGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCACTAGCATTACAGGTGCTTGTTTCATGAGGAATGGGGGT
+
F@'BACDD@?EFHGHGG@GIII@BIIIEDDHI??I@ABGGB?@E@BHDFDHI?DFA?B@HEI*DCE?CHDAAAE@BEDADCEB>HIE?FD>CICA?D@CD
@>chr21:9704828-9704956-4
ACCACTATGTCAGCAGGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTANCATTACAGGTGCTTGTTACATGAGCAATGGGGGT
+
CBEACCAIHB?AHEIFF@FI?@IEAEEFDDAG?@DDHCBBHEA?F?IHF@AEIACIFEIHHCAGD+@CFCHIFFG@@?G@GBHEIFBBIB@IB@GB@GHF
@>chr21:9704828-9704956-5
ACCACTATGTCAGCAGGGGGATTGCGGATCTTATAGTAATANTTTAGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGGGT
+
ACBIAIE;I???IFGEHAB@ACFDBHF@@F@?ECF4ADAFF-CH?/?DE?AEAE@DHIGB&AD@?IHBAAH@CDAD@ECB@?DD?EFFA??ICEC@EDFB
@>chr21:9704828-9704956-0
CTCATACCACGCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAA
+
@G?@CAC@H??EBCGDICHB@EFGHHBFGEGC?AICDACCIGF?IDDH?CBBFGHICFBBIHFFI@AFB@G/ADE@GHG?C@CCI@@E@FAF?EA?FH??
@>chr21:9704828-9704956-1
CTCATACCACGCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAA
+
DFCIGGEDHCECHFEI@E@DE@CGCF@FFEFHCEAGIHCACFCIBDF@@HAHH?EEGDBBCHGDEEGECDIGG?AIDDBBHCH@B?CI?BDIAGA@GAFE
@>chr21:9704828-9704956-2
CTCATACCACGCAGCAATCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAA
+
@CB?BBHIF??CHHGF"GAAAB?F@D@CCECFDH@C?EFE?DD?FAIAHGFBD?A@DBD@GH@EDGHD?I?HG?G?@FDHH?@HBIF?BCDGFDGFI@G@
@>chr21:9704828-9704956-3
CTCATACCACTCAGCAAGGGGGTTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTANAGGTGCTTGTTACATGAGCAATGGGGG
+
AFIBEIGAD@%BAAFEF@CID%?BHBBDGDEDC@HCF@AEF@A?EG??AAIGDII@??FIIGHHE@AGD@@C3AA?E?F@HEBBBBG@HEA?H??HE?A?
@>chr21:9704828-9704956-4
CTCATACCACGCAGCAGGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGGG
+
IC?HG@G?AIG@BIFAIC?GHDGHD?BCEFDD?G?GGBCBEEEIDDAICEHBAHAICIBEAAEDGH@IGCC?EGEGACABAIFBHA@FFD@@FHFCHHC@
@>chr21:9704828-9704956-5
CTCATACCACGCAGCAGGCGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATGAGCATTACAGGTGCTTGTTACATGAGCAATGGGGG
+
EHGAEDGFIEHDBHIIA@"CD??EE?DCCGC?@CGDI@HF@CG?H@?BHCEEBFIDAAG?I??@.CIHCDCDEGA?GDC?BABAIFEAFI@AF@@?GAEE
@>chr21:9704828-9704956-0
GAAGGTCCTCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTTCCTCAATA
+
DH@DIG?GE?EIDH?CHFCBA@EIII@FAC?GA??BFAAAIDEAIGCHF@?FDCAHAAEBHH??HIEBI??D@BDCHF@BEGA@GBCADAD1I@F??BDE
@>chr21:9704828-9704956-1
GAAGGTCCTCAGCATTCCTAATGCAGANATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAATA
+
GGCAC@DAC@C@H@IFHBEIIA?HEGI.AAGBIA??FDEH?BF?IG@BECAEDHIEIGBAG@HACFIGEHHCCGH??BECGEHD?CEIC?FEBGIBFAI@
@>chr21:9704828-9704956-2
GAAGGTCCTCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTNATGCTAATGCACTGCCTCAATA
+
HFIEEE?IGCG@BH@DEE??BE+CEHCBD?ED@GHFDEDGDGHABGAFFGHGIAHCCCEIDBH@FFG?FIFG@AFH?;H?CE@AHGA@IH@?H?HII?DF
@>chr21:9704828-9704956-3
GAAGGTCCTCAGCAAGGGGATTGCGGATCTTATATTAATATTTTTGTATTGTGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGGGTG
+
ABH?DAI?@DI?HBFA@C@AIDC@CABCD@BDA?IH?FFCB?E@IEBBIEF(@@CHC?@DHF?HGG@AIG@BHFDFGDF??D@FBBBDBI@D?BD?EFFH
@>chr21:9704828-9704956-4
GAAGGTCCTCAGCAGGGGGATTCCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGGGTG
+
FCFFA@HBI@BCDDFHEFDFIF4ED@IDGICFGI@BBIIECICAE@EFFHHAG@GA@A?@CHBFBGCCHDGCEAG?DHEDCHAFIBGEF?EHDAFA@HAA
@>chr21:9704828-9704956-5
GAAGGTCCTCAGCAGGGGGATTGCGGATCCTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTCACATGAGCAATGGGGGTG
+
AGICDCFBCAGC@BCGCDHGB?FBAD@H@-@HEH?HDGBFCEE@BDCIDAC?ECFDGBEHGHECEHFEHDDEF?A@GGA@E=BAHG@IE?ECEBAEF?I@
@>chr21:9704828-9704956-0
GCGGCNTACAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCANGTAACAAGCACCTGTAATGCTAATGCCCTGCCTCAATAC
+
EHIF@9A@C?@AAIC@IE@FGBFCAF@BFBCGEDFGA@@GF?CEAB@IH@B@DEH@GHDC&B@@I??FGAGHB?DDGHBGIFE?AFI>@DBFGGGBADFB
@>chr21:9704828-9704956-1
GCGGGGTACAGCATTCCTAANGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTANTGCTAATGCACTGCCTCAATAC
+
A@C?!EDBGFAGBBCAHEG@-EHFIAEICFDHHD@@AGFBBFIBEBCFFCGAEEACHCCDDABC??@AHAIEFAIHC(@ADBIHEB?CIDG@BA?ECIH?
@>chr21:9704828-9704956-2
GCGGCGTACAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAATAC
+
IAIF?DDHAFAADIIIIAAEHCA@CEBACAEABFBBDHAFEACAHCEFHI@GECGB?GAEH?G@B@AGH@HGIAEHAGDED?IHGF@FIFIIDBBE?CHB
@>chr21:9704828-9704956-3
GCGGCGTACATCAAGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGGGTCT
+
IE@GBC@EFC9ICHCHAEFGCE*CEBAABF?BCED@BDFBDCDEGDD@AEGHBEHGGI@AHHGAFAHH?CAF@GA@FH?I@IHABC?C@A??HFBCEE6F
@>chr21:9704828-9704956-4
GCGGCGTACAGCAGGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAAGGGGGGTGT
+
?,EFH?DIB?CHCH@@FDGIBHHCHDI@DBGF@HGFF?BDDG@HIID??DDIDEH?IACEDCAIAGGGFI@B?HH"EEFEFCGIA@?FHGD%@EDEHFAG
@>chr21:9704828-9704956-5
GCGGCGTACAGCAGGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGGGTGT
+
CGIDGGAB@HAFDGDGD?GG@F@GF@BAICIFDDG?@I?HDCCAE?IGAI@?@EEGB?AI?FAA@DI@@@GCHA.ABEBDD@DD?ED?IHIABFE?IGDI
@>chr21:9704828-9704956-0
TCAGACGGTAATCAGCATTCCTAATTCAGACATNAAACCCAAAATATGACACCCCCATTGCTCATGTAACACGCACCTGTAATGCTAATGCACTGCCTCA
+
CAE@BCEBFEBHEIHBGCIAEF@IE'??F?HBE/B#HHHGBA?@DDA@GEEAADHECH?EBIHH?CH?H?B3DGEGG?GIEIEIHDDEIDI?IFBFICEF
@>chr21:9704828-9704956-1
TCAGACGGTAATCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCA
+
HCDH@?C?HBFEB?CDIGEG@HFA?@ID?IHAIG@DHIHIBHD?BAB@ID?AH?B@G??CIHGGDDCH?FBH@CGIACB?BCIEBDFABIAFHDEE?HG?
@>chr21:9704828-9704956-2
TCAGACGGTAATCAGCATTCCTAATGCAGACATGACACCCAAAATATGACACCCCCATTNCTCATGTAACAAGCACCTGTAATGCTAATGCACTGGCTCA
+
AD@G@F?G?IA?CGGBFD@FHAB?G@?HB?HB@E@FAC@@BBH??DHHABCI@?@H@(G/GCAEEG?AA@HHHAAEAAIF?B?HDCECBE?HD@?5GCBG
@>chr21:9704828-9704956-3
TCAGACGGTAATCAGCAGGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGG
+
CB?I?ABD@AGDDGAE?DA@@?ECFIHHH@IH@C?EHF?B@EBIFFHCHBEFBB=GBEEHACD?HD?HF?IIEDFE@@H@HADCFGGD@?EDC@BGEC?C
@>chr21:9704828-9704956-4
TCAGACGGTAAACAGCAGGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTANAGGTGCTTGTTACATGAGCAATGGGG
+
CHDCGFAGACA/HB@HBEFD@BBH@B?DBFCFIFHFDF?@@BI?@IAHBD?E@DGIEDCEAAGGBDC?FF?H@>?IC?FFADDHA@ABCCB@??EFAHGE
@>chr21:9704828-9704956-5
TCAGACGGTAATCAGCATGGGGATTGCGGATCTTATATTAATATTTTTGTANTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGG
+
@C?@A@HAD@?FI?D@H8GD?EEFH??CEDF?A@?D?@CHAAFFFHAI?CE2GA@BCB@?ICAE?:EECCE@EIBA@G?BIGGH?IBAFAH?BH?I?@BF
@>chr21:9708161-9708285-0
ACCACTATGTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTTACCCNCAGGCCTGGCGCGCACGCATTCCAGAGGCCACC
+
DFADDG??HACEBABCFD@GB?IHBDDDAAD?GFGFGFFDBBEGEBDHBHF@CI?BH@??G!BGHB!DIBIHAAD?FIA@CFBIEEIIA@@AIAIEIDH?
@>chr21:9708161-9708285-1
ACCACTATGTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCGCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCACC
+
HEGEE?@I?EG?AFEI@DBDDCBDG@EHDHHCAB?HHIF@EDCBAIBGFGA'HHBA?CEAID?BGDGGGHDA@HGGI?EECBDH?DIDAHHCAFCICBHI
@>chr21:9708161-9708285-2
ACCACTATGTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCGTGGCGCGCACGCATTCCAGAGGCCACC
+
GD?AFF@?AFCBGGCEAIBCG?@EGIGHC?CGFGI?FE@?CAHFDEEAEIG?EFABDGAIDEEGGD@C?@EC;EACI?ABIGGDEACBDFDFGECAIDH@
@>chr21:9708161-9708285-3
ACCACTATGTCAGCTTGGGTGCCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGCAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCACA
+
@IGFBAB?CF@CBGAF?FD'CIHFGFDAC@DEFAFCGCAFBIEIBEA??IIIEAI1G?HFIEHHCGF??FBGIFGC@C@AHFGFFC?HBIFCAHGIEEHA
@>chr21:9708161-9708285-4
ACCACTATGTCAGCTTGGGCGCCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCNGAGGGTCACCCTCGTGGGGCCACA
+
D?@HDECHGEEEBCGDAF@A?HG?FBDI?ACCIHFCHAFHEDBGAGI@??@IIAFEDG@DID?@?HA?DDEHHG@-HD@GFDBBC@DA<@EG?BICCFDE
@>chr21:9708161-9708285-5
ACCACTATGTCACCTTGGGCGCCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCACA
+
GB@@CIICDC@I7CH@EHH@AFE?EDFAFAFI?CDEBCEBE@BCGBACAH@EGDFF@?@?C@GC?C??HDDGFAHFDH@I?EHGAEDFEIGG@@HABEAC
@>chr21:9708161-9708285-0
CTCATACCACGCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTCACCCTCGGGCCTGGCGCGCACGCATTCCAGAGGCCAC
+
GGB@?GH@EACFH?AHHFHI@DC@AEICI??@A@DI?B@H?HDFBCHIFCFI?CEGIIHDF?%IFEGA?1FHAFHDBDAHGFCBGIHBCCHAADIEGEDA
@>chr21:9708161-9708285-1
CTCATACCACGCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCAC
+
IDDDAGHCHDFHADHIFH@@?AEI@ADBDGEGBDFA@?C@CE?F?@CHE@IBGCBBDEEEIFGEFDGDGCHEFEADDBGAEGBBGBA?B?@?@D?@HGBE
@>chr21:9708161-9708285-2
CTCATACCACGCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCAC
+
HAFIIAHIHCAABI@"?AEFFF@I?BCE?GAEFFIH?F?HCH?IHDCGF@DCAGBCG?CCCBDAACHCE?GEEIEIGI@?FEE@@CIHCFFIH?@DAAAG
@>chr21:9708161-9708285-3
CTCATACCACGCAGCTTGGGCGCCCAGATGGGAGAGCATGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCAC
+
F@ECIFBACECCHG?FEBEGCGFD@?@?G?A0BH?HD@FFHCA#H?BI?DAGAB@?D?GD?@EEC?CIF??DA?FDBI@IGHIBAD@HD??CA?GADAEC
@>chr21:9708161-9708285-4
CTCATACCACGCAGCTTGGGCGTCCAGATGGCAGAGCATGGTTTGGGTGCCCTCTGGAATGCGTGCGCGCCAGGCCTGAGNGTCACCCTGGTGGGGCCAC
+
AA@?G?DE?AHIDICGCIBHBGFAADC?DCB@EF?B@@HCAF@IG?BBD"BEH?FCHCGI@HBBBH?G@EDD@CBACDGC:?H@FFADED?IEF?GEFGF
@>chr21:9708161-9708285-5
CTCATACCACGCAGCTTGGGCGTCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCAC
+
?EFHFHHHFHEB@B?@EGAG+I?AIGAD@CGD@FAE@AGH@HEHBEHCCFBHFHB??BDBGEBEDB?FHEAIHHHCAE?CDHFFFBGDBC@G?II?HBCC
@>chr21:9708161-9708285-0
GAAGGTCCTCTGCTCCAGGCTCCAGCAGGGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGNCTGGCTCGCACGCATTCCAGAGGCCACCC
+
IDE?GAGEI@IFAD@E?ECFI@H?EIG?>CIAAFDAFDEDCDD?BGDHD@CH@BIEIADBGEFBCCEBHF1IAA@?&HBFCFDACEDCAC?CFHCEF*AI
@>chr21:9708161-9708285-1
GAAGGTCCTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTCACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCACCC
+
B?GCDGDEE@AABBA@?E@EIH?DBDGG?D?BDFHFHD@EDGGCEBHBCHFGGEEBEGHE>B@?GEHDBFHFBIA?@AFIIABHGFBBA@@ECHCHHF@I
@>chr21:9708161-9708285-2
GGAGGTCCTCTGCTCCAGGCTCCNGCAGAGGAAGACCGGGGTATGTGGCCCCACCAAGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCACCC
+
B=BG@EG??FIC?CD?GFI@BC@0CDHDHIHG?B?AFACE?IGICBEA??GE?ECH-IBH@FGEAGE??HCBF@B@DF@C?@ICFBIAACDFHDFDHF@C
@>chr21:9708161-9708285-3
GAAGGTCCTCAGCTTGAGCGCCCAGATGGCAGAGCATGGTTTGGGTGNCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCACAT
+
HCGDA?CEDI@BIIGI,BH?GDEDEA@@BDI?EAE@BGH@C?CCIDI;DC@IB?F@BFA?GBAE?IBD@EBBBDIEEAAECCBF?EED??CEDABFBFG5
@>chr21:9708161-9708285-4
GAAGGTCCTCAGCTTGGGCGTCCAGACGGCAGAGCATGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCACAT
+
FDD@BHFIGEE@AH@GICF@BGAGGC=AGI@GB@BD?FH@@DCGDHFHAFCHGB@@EBCHIAD?HE@DFBHBGE@E?F@DC@HFDEI?HAE?HEEEFHHI
@>chr21:9708161-9708285-5
GAAGGTCCTCAGTTTGGGCGTCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGTAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCACAT
+
DBACDEAGIFIE*CIIADHCCEB?HGFBGA?D@BEBDBFBCGCEIDIFF????D>H@DDFIA?AEFG?ABGDHF@EEEAADE@FEAAG?DIHIFGFDH?I
@>chr21:9708161-9708285-0
GCGGCGTACTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCACCCA
+
GH@@EHAGFBCAEIGCCAC?@FACDACGFEGIAG@G?CIIHH?EEFEG@BHGA@@@HII?EGBHC?DHCE?C?F?EIDB@EDIACAFAEBCBH?ADEEF?
@>chr21:9708161-9708285-1
GCGGCGTACTGCTCAAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCTCCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCACCCA
+
AI?AHBBI@CD@DH9BGIDDABGH?AIGCE@FBC@ABHHF@DH@FEHD6@GCH?DHH?FBAECEFIC?@?IAAIGFE@GB?BDDGDAFBBBACE?EEEHE
@>chr21:9708161-9708285-2
GCGGCGTAGTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCCTGGCGCGCNCGCATTCCAGAGGCCACCCA
+
HGF@GAE?;@AEIDD?EA@?H@FIF@@DF?AGD?B?ICFDCIFDAGC@@AFDDCBE@FADI?@D@H?C?FADG@?CDA@'?CE?DG@CACGGGHEBGC?D
@>chr21:9708161-9708285-3
GCGGCGTACAGCTTNGGCGTCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGCGGGGCCACATA
+
G?EA?D@I@GB?EA<I?G@GHAIG@DAEBAGEDHGGHIECBEBEBGEHADGG@AHEAGGEBGGCGIDCBGCAFG?BCADHF?HI@???,FAGGHEDG@?D
@>chr21:9708161-9708285-4
GCGGCGTAAAGCTTGGGCGTCCAGATGGCAGAGCATGGTTTTGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGCCCACATA
+
BHDHCDIF%FGC@CAGB?IHD@HEAAEDAGG?D?EIHDCI@3IHCFCDDGDAIIBFDIIHBA@CC3@@@?CAHGBGBB@??AHFBI@EC@FD-DIEH@CB
@>chr21:9708161-9708285-5
GCGGCGTACAGCTTGGGCGTCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGCCCTGAGGGTAACCCTGGTGGGGCCACATC
+
AGIBAHFCDAHHIA@IB?AIBGBA?BACABAB?HAD?DBE@HF@DE@HHCAEGCIEFGCA@CFHI???AF$B@@EDI?DH.BAC?E?IGFCBFH?BCFE;
@>chr21:9708161-9708285-0
TCAGACGGTAATCTGCTCCAGGCTTCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCA
+
?HD?DIFIGIHG??ABHEFAAFFH,GGFH?BB?FDCCBDACFIH?ADHA@GGABHD?H?F@CGE?IBB@BIEDGEB@DEDBBHGCAEH?IEHBH?GDAIA
@>chr21:9708161-9708285-1
TCAGACGGTAATCTGCTCAAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCA
+
GHEDADG?B@DGBI@IB@%CHCGICCA@DCEEDA@BBC?FHCACIAAD@HDEC?B@CGEAHH?DB@A@FFACBDBE?E@H?CECF@FEC@@IFCAEAEH?
@>chr21:9708161-9708285-2
TCAGACGGTAATCTGCTACAGGCTCCAGCAGAGGAAGACCGGGGTATGTGGCCCCACCAGGGTGACCCTCAGGCCTGGCGCGCACGCATTCCAGAGGCCA
+
A?@?BDGGADGDII@DB4DHA@CBHBF@EI@GABCB?GIH?ADIEIEB@IIECIABBFCEHCGCIG?G@B?F?HEG?F@FE?HH@@DIFF?F@GHGGDG?
@>chr21:9708161-9708285-3
TCAGACGGTAATCAGCTAGGGCGTCCAGATGGCAGAGCATGGTNTGAGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCA
+
@@CEIC?A@GHC@GGGB)CEHBGA@GBEBAC@DFC?F?ADCEE$G@>DAGGIFEF?FDC@FB??DBG?DAIFID?GHA?IHBHGFFF?HCCADAFB@H?F
@>chr21:9708161-9708285-4
TCAGACGGTAATCAGCTTGGGCGTCCAGATGGCAGAGCAAGGTTTGGGTGGCCTCTGGAATGCGTGCGCGCCAGGCCTGAGGGTCACCCTGGTGGGGCCA
+
E?FIDD@B@H?EHCEBIDDHBAGII@CDD@DBCIAHFDC(E?AHABEF@CIGGD@??BGGHF?HEE@GCIAE@II?F?EEAFEA@G(B?IEH@EBGABGC
@>chr21:9708161-9708285-5
TCAGACGGTAATCAGCTTGGGCGTCCAGATGGCAGAGCATGGTTTGGGTGGCCTCTGGAAGGCGTGCGCGCCAGGCCTGAGGGTCGCCCTGGTNGGGCCA
+
AIEGHCA@DDE@IFB?ADEB@E@I?H?@?FDGDE@@@G@?IFE?EBEHBCGH@AH@FFE?/BF?E?B@B?FB?CCGGC@IIHI?F)G?FG?B?+?BCA@I
@>chr21:9708306-9708383-0
ACCACTATGTCAGCATGTGCCTGGCAACCCACGAGCCCGCTCGCGCTCCTAGCAACACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGANCGGAAGAGC
+
A?@?FAGE?@AFGH?FDEHF?F??HIBIA@8FAB@FBAGCCHG?E?BF?BEDHI1@HIBAFHHHIDDHBF@?AHFCAG@EEACIAEF@GG=CHIGGHE'A
@>chr21:9708306-9708383-1
ACCNCTATGTCAGCATCTGCCTGGCAACCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAGC
+
B?G6D?@C@AICC@HCI@CC?AGA@GFEHGAD?EF?IF@IEED@AB?B@?GBICDBIHBFAD@FCEGC@FIEIED?GBAA@@FIFF?F?B@ICI@AEEAD
@>chr21:9708306-9708383-2
ACCACTATGTCAGCATCTGCCTGGCAACCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGAAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAGC
+
HFGI?C@HIIGICGC?IH@A@DHIBADCEF??@EB??ADFGFIA@DBHAD?FAC@FBC@IIBF*FE?@D@BCD?@GHEAIADEEFFCHFIDHCDBF?IEI
@>chr21:9708306-9708383-3
ACCACTATGTCAGCCACTGGNACACGTGGCCCTGCTTCTGTGATGCTAGGAGCGCGAGCGGGCTCGGGGGTTGCCAGGCAGATGCTGAGATCGGAAGAGC
+
ECGDGEGAAAAIAICEA?DI<DB?DDIAAB?BCDHDFC?B?AHEIIHFEECGBECEIF?BEGAAB@IGBBCHFID@F@@IBCB?IGCBD@GBBFAHACHB
@>chr21:9708306-9708383-4
ACCACTATGTCAGCCACTGGGNCACGTGGCCCTGCTTCTGTGATGATAGGTGCGCGAGCGGGCTCGGAGGTTGCCAGGCACATGCTGAGATCGAAAGAGC
+
BCBHEHIG@FGIDD?G@FEE@/GFD@ACIBE?A@ABFGAF?@DGD.GEEH-FA@BHIEEGBFEIEDE(CBCA?GDDEDFDAC?EIEFB?IFAB'ACICHE
@>chr21:9708306-9708383-5
ACCACTATGTCAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGTGCGCGCGGGCTCGGGGGTTGCCAGGCACATGCTGAGATCGGAAGAGC
+
DDHDDIAH??FFIDGCH??CDDCHHFE@FFGEG@DH@IBHHIBCEEIAEI?G&DHG;HFDEGE@E?AD@DBB?IF?@EG?B@@FCED@DACGACA?DBAC
@>chr21:9708306-9708383-0
CTCATACCACGCAGCATGTGCCTGGCAACCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTNGCTGACATCGGAAGAG
+
?C?GDBBAIFCHAAGFBIDAIIEFAFIICF?CHIF@AIGFAAG?ECCC?HFC@CD@I?DC?CGHIFDIFFG@G@H@ID?@EEA%H?FIH=CCIBA??H@?
@>chr21:9708306-9708383-1
CTCATACCACGCAGCATCTGCCTGGCAACCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAG
+
ACCFEDA@BBHC?BBBDB?I??H@GG?@BBIA@?FGDCAFEHDGI@AII@AICFHFIGGEHCC@B?EBCI?GGBFGI??B@FFHADBIFFE?DDHAGCGC
@>chr21:9708306-9708383-2
CTCNTACCACGCAGCATCTGCNTGGCAACCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAG
+
AFA5FH?DEE?D@CBF@B@?G5?AGHHA@D?CFFDHH@IE@B?IAFA@ECABBEDH?AFEIAH@AI@H?ADD?IIBEE?@HBDD?DBBBC?@DGC?ICCA
@>chr21:9708306-9708383-3
CTCATACCACGCAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGCGCGAGCGGGCTCGGGGGTTGCCAGGCAGATGCTGAGATCGGAAGAG
+
?BB@CDI?CDC@@@EF@F?@C@BF?@?A@FBBBABI@GGFDHF?@AB@D@E@HBBIHHH?FEDCBHAEED@ABBF@G?@?BE@CDEIIIGHCGFDI@AHG
@>chr21:9708306-9708383-4
CTCATACCACGCAGCCACTCGGACACTTGGCCCTGCTTCTGTGATGCTAGGAGCGCGAGCGGGCTCGGGGGTTGCCAGGCNCATGCTGAGATCGGAAGAG
+
HA@EHCCEF?@BE@HFFAD&@CICHA*GED?HDEHIHHE?ID?ACHEB@??FC?HE@IFH@C@FC?AA@FADHDEDEAHE,?CCIDG@?FE@HFBEHBHC
@>chr21:9708306-9708383-5
CTCATACCACGCAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGCTCGAGCGGGCTCGGGGGTTGCCAGGCACATGCTAAGATCGGAAGAG
+
HD@?C@IC??C@?BFCFGGABIIDCDDHC?@BGECAH@EDIG@AIHGGIBIFEI5EI@IBGHCDFHBDD@@FIB@EBF?IEFABEFG4HI@FIB@AFB?F
@>chr21:9708306-9708383-0
GAAGGTCCTCAGCATCTGCCTGGCAACCCCCGAGCCCGCTCGCGGTCCTAGCATCACAGAAGCAGGGCCTCGTGTCCCAGTGGCTGAGATCGAAAGAGCG
+
FH@CCHCDFCBAGA@C?B@DGD@C@IGEACEBEBGHEIE@?HBB1EEH?HAFF@I@HIG?HFCA@EGDD#GDGBDGE?DBCGADEEBHIE?I&??FICH?
@>chr21:9708306-9708383-1
GAAGGTCCTCAGCATCTGCCTGGCACCCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAGCG
+
EGIIBFCBG?FAIGH?EEIHAGC?H&@FIH@?BC?GACEAEHFG@GBHEGBAG@DC?@BAGCCDF?ECBABD@DHCECAHBI@CCFADEGH?EFH@F@AC
@>chr21:9708306-9708383-2
GAAGGTCCTCAGCATCTGCCTGGCAACCCCCGAGCCCGCTCNCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAGCG
+
FAFBFFCD?EFBDC@CGCGFCCABDFHIIHCGBDC?B?IHH5CH@I@?CFHEICDCCDGI@HI@HEFBAEHDFEDFB@EAGCIB@CIGHFBCCABIBC?F
@>chr21:9708306-9708383-3
GAAGGTCCTCAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGCGCGAGCGGGCTCGGGGGTTGCCAGTCAGATGCTGAGATNGGAAGAGCG
+
CHEHAGD?EIDGCACF?FAG?FCGDA@IDHAGHBHCB?EFE)HAFDD?CAAIBADFDIHECIHDFFBCGEDDC@?D%IHH?@C?G?C@CH=CDHGCHDHI
@>chr21:9708306-9708383-4
GAAGGTCCTCAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGNGCGAGCGGGCTCGGGGGTTGCCAGGCAGATGCTGTGATCGGAAGAGCG
+
ECFFGFF?C?H@DBGA@DAFGDHCHBGBIIFHHD?C?C?DIFIABCEGCHE3GIEA?G?DCGD@EFHDGCFAGG?FGEEAEDIGCH*HEFA?H@?EHGGE
@>chr21:9708306-9708383-5
GAAGGTCCTCAGCCACTNGGACACGTGGCCCTGCTTCTGTGATGCTANGAGCGCGAGCGGGCTCGGGGGTTGCCAGGCAGATGCTGAGATCGGAAGAGCG
+
FFHFG?A@FD@IG@I?@$@A@CGF?AEA?HEGBEBCCF@FHCCF?@F:EIGFBEBACFBCD@A@B@CFCGBHBIGFIDAIDIDH?DDHD?GF@GHG@F@H
@>chr21:9708306-9708383-0
GCGGCGTACAGCATCTGCCTGGCAACCCCCGAGCCCGCTCGCGCNCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAGCGA
+
?AA@?FFFBGFF?H@@?IFI?HEDBCFAH@F@GGBEGDFHADAG6?@DEI@GB@IFIICF@DBGBEICHIBADEF??IDGGEHIAB?CHGI?EGGAHI@C
@>chr21:9708306-9708383-1
GCGGCATACAGCCTCTGCCTGGCAACCCCCGNGCCCGCTCGCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAGCGA
+
FFB?D$CFDBEF)@GGDCAHBIEFHBE?I?C)@HBEIDC@F?HF1CDDIEFIHG?IGBIIEBHICF?CF@@AFADBCFABEIIIABG?BFAAAACHB??H
@>chr21:9708306-9708383-2
GCGGCGTACAGCATCTGCCTGGCAACCCCCGAGCCCGCTCGCGCTCCTAACATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGAGCGA
+
BF?@DB@BCIBGIBCGGC?D@IAG@@A@??AHDIDBIEB@AC?@GCFEG'ABGCIEEI@BBI@ECBEDF?AGGHEGH@DFEIHBACGBDCFCCFDCBAC?
@>chr21:9708306-9708383-3
GCGGCGTACAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGCGCGAGCGGGCTCGGGGGTTGCCAGGCAGATGCTGAGATCGGAAGAGCGA
+
B@@ADB@FDCDICD?AGDA@GG?EHHIHBBF@CHB?EED@?HHFEFGAC?A??B?DBD?EA?EIC@FHFE@DBB@@DDBDG@?E@EF@GAFHBBI@@A@G
@>chr21:9708306-9708383-4
GCGGCGTACAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGCGCGAGCGGGCTCGTGGGTTGCCAGGCAGATGCTGAGATCGGAAGAGCGA
+
DHABE@CG@DB@AHAECCHHG@?EH?DHIHFC@CII@BFED??BBE@DBHIFCEFGHI?HI?AE%H@BB@@GAHADBD@AFABFHBBB@EIDEGEFCGCA
@>chr21:9708306-9708383-5
GCGGCGTACAGCCACTGGGACACGTGGCCCTGCTTCTGTGGTGCTAGGAGCGCGGGCGGGCTNGGGGGTTGCCAGGCAGATGCTGAGATCGGAAGAGCGA
+
GDHFBIDCE@FHAEFBICFH@BCEIHECFDGE@GBDGGBA(CAAE?I?B@AGII>?F@EIBE/IEAIGHCIAHE?DIGIE@IC?FBEIGDFFGC@GGFED
@>chr21:9708306-9708383-0
TCAGACGGTAATCAGCATGTGCCTGGCAACCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGCNGGGCCACGTGTCCCAGTGGCTGAGATCGGAAGA
+
III?H?@ACDEFF@GEEDEAFEEFFICEIGEDFDGHBEEB????HFAICFHABAIEHHFFCDI?AH<IBFBBC?AFCGHDEBADIGAEIDAHDFAB?F??
@>chr21:9708306-9708383-1
TCAGACGGTAAACAGCATGTGCCTTGCAACCCCCGAGCCCGCTAGCGCTCCTAGCATCACAGAAGCAGGGCCACGTGTCCCAGTGGCTGAGATCGNAAGA
+
GHBAGB@BB@D3HFADBH@H@HIE$CAFGF??FHCH@B?HBEI6BA@@BEAC?HDEBICEDEB?@?@GBDHF?HIBBEFFGACDF?IBHFHIAEA"DEFF
@>chr21:9708306-9708383-2
TCAGACGGTAATCAGCATGTGCCTGGCAACCCCCGAGCCCGCTCGCGCTCCTAGCATCACAGAAGCAGTGCCACGTGTCCCAGTGGCTGAGATCGGAAGA
+
BH@IDDIBBGFG?@?AIBGF@D?@??BHAFIAI@CAHGE@A?DCHC@AEEGAFHDAFIBIHFDGDGA@2BDFDEGACHC@CABDAG?IFCGGIHAEBGGE
@>chr21:9708306-9708383-3
TCAGACGGTAATCCGCCACTGGGACACGTGGCCCTGCTTCTGAGANGTTAGGAGCGCGAGCGGGCTCGGGGGTTGCCAGGCACATGCTGAGATCGGAAGA
+
?HAHEDBAD?@CI3B@ACFHFCEDH?E@E?AHDD+AAEGI?@9DB;C1DABEEEAE??FGDFCCB@IFBGDIIB@AEGHBBGBIDG@@A@BGECB@F@B@
@>chr21:9708306-9708383-4
TCAGACGGTAATCAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGNGCGCGAGCGGGCTCGGGGGTTGCCAGGCACATGCTGAGACCGGAAGA
+
AH@HIHIAECAGBBFGAA?@?IIHBGC@@HAICBEECAD?A?GACGABDDI?:@ACDDAAIAEDBEGIB@F@CG?D?DG@CHFFEFE@H9?C5HGHAACB
@>chr21:9708306-9708383-5
TCAGACGGTAATCAGCCACTGGGACACGTGGCCCTGCTTCTGTGATGCTAGGAGCGCGANCGGGCTCGGGGGTTGCCANGCACATGCTGAGATCGGAAGA
+
EGAI@@@DG@CEH?I@DH@GIBCHGGEGC@HGEBHAHCCECCEFIE@BDIGIEGIE???8AFBCBHGCHG@EHBCAG?5CEAGGBEDFDDHEIG@HIGHB
@>chr21:9708417-9708616-0
ACCACTATGTCTGCCCAAGAGCCAGAACTGAGAACCCACCGCTCAACCCCACACGAGTTGACTGCCGACTGCCCATATAAACGGCTCCGATCTCCCCCAG
+
?CGA@@?FHHDGBCFIGFEIGF)CFACIBFC@@DA@ECIFC@@BHBIHFGC?BACC?;@EEI?FC@DF)BEG?ICECCGIBHFI@H@E%EHDGCBC1GGF
@>chr21:9708417-9708616-1
ACCACTATGTCTGCCCGAGAGCGAGAACTGAGAACCCAGCGCTCAACCCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCAG
+
BGDDECD@@CEAFHBE7E?ECIBFEFBGAIGGIFFCB@:BICDHC@BH@GIBH?FEDECC?DE@GFCBBEF?G@HG@@HDCIA@??AIBHC@FA?E?GFI
@>chr21:9708417-9708616-2
ACCACTATGTCTGCCCAANAGCGAGAACTGACAACCCACCGCTCAACCCCACTCGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCAG
+
D@AHIGCG?H/?FGFB@E*BE?FHG@CCAFG9HEBFHCHEBAH@HBC??BFA7FGIB@F?AFABDID@IFCCHBCBD@HAEIGIB?DE@FBG@HDD@EFB
@>chr21:9708417-9708616-3
ACCACTATGTCAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCAGAGGGCCCCCAGGCCATGC
+
BD?H?@DC@FCDGIBCEDCDF?A?IHGFD@C?EEED@I@G@BEG9ABI?DACAF???@@FGFC?@HDHE@IHDIHHFDFG"FB@@DG?BFF@HEHD@AAF
@>chr21:9708417-9708616-4
ACCACTATGTCAGCTCGGGTGCCCAAGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCATGC
+
IEFADDB@E?DE@?AG?C@@EBII?-@?@BDHFIG?A?BHAGDG@I?DDAF?EIIAG@D?B@I?IEI?G??ICFC?BAGF?A@CBAE@D@ADHFCHHFD@
@>chr21:9708417-9708616-5
ACCACGATGTCAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTTAGGGCCCCCAGGCCATGC
+
GCA@F%GEFGGIFHGBEIH?@ADHII?IGGDG@EAFCB?IIIDEIIDFI?GCI?H?DFGI?DDHHBFH@DF9BGFEFBDHD'ABIAIGEAI?DC@A?F??
@>chr21:9708417-9708616-0
CTCTTACCACGGTGCCCAAGAGCGATAACTGAGGACCCACCGCTCAACTGCACACGAGGTGACTGCCGAGTGCCCATATTAACGGCTCCGATCTGCCTCA
+
BED8DBFFFB@<CC@IDICIAAI@?#BEDIBHG:IIGBFIGACFCDED&<@DEECEFECFI@HHDAHFIFHDAIIEID?<GCFCGHEHHFHIEC#DBDGB
@>chr21:9708417-9708616-1
CTCATACCACGCTGCCCAAGAGCGAGAACTGAGAACCCACCGCTCAACCCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCA
+
CEGDEIGDFHEFDDHCC@EIB?ABD@GGBIC@EHFBBIIIGAAFICBHAF?DDCA@DAED@G@@DGDDGHCBEA@A?FBFI@CGHCF@?CF?@IF@BGAH
@>chr21:9708417-9708616-2
CTCATACCACGCTGCCCAAGAGCGAGAACTGAGAACCCACCGCACAACCCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCA
+
H@AACCCFFBHDGB@DA@HBCH@BC@BB?IBHG@BGFGH?B@E1DHBGEAA@IE@ECDAI@BAHC@IF@IEE?CBI@AFBHDG?AI@FHFIDGDBBABBD
@>chr21:9708417-9708616-3
CTCATACCACGNAGCTCGGGTGCCCAGGNAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGGGCCAAGCCTGAGGGCCCCCAGNCCATG
+
ACIEFFADIAF3IDI?FDFGDFBDCHDF0ABI@AHHG?CBDBIHBHGIEIGBDFG@AA?@CD?FIEDEAHEA(AAD@BEBIHGHAIEDH?BFBE6DIFB?
@>chr21:9708417-9708616-4
CTCATACCACGCAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCATG
+
CFB@H@IC??DEE?GFBAH?BCHAECB@FDG?IFGCEDBGE????EAF@EDGCDFIFHADD?DDAFHAFICGDBEAHAAABCCCG?DGDFGFB?HBDA@B
@>chr21:9708417-9708616-5
CTCATACCACGCAGCTCGGGTGCCCAGGCAGGCTGGAGGNGCATGGCCTGGTCGGCCTTGGGGTCGCCAGNGCGCCAAGCCTGAGGGCCCCCAGGCCATG
+
BEH@IC?FIC@EEDGED?CIF@@@CA?AEEH?FCHDGBI+DCDFGH?GABGBBCDF@DHHHD=BCBGAEI/EHH@@F@EIH?HHDICFHGGGH?ABF@B?
@>chr21:9708417-9708616-0
GAAGGTCCTCTGCCCAAGAGCGAGAACTGAGAACCCACCGCTCAACCCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCAGG
+
DD?B?GA?II?AIHDCHBFIA@BEICAA@?I?ICAG?GBG@AECA@?@A@@HGCEII@AG?BHCBEHA?DAGIABF??CG@CC?AEIEBH@G@IHADGIG
@>chr21:9708417-9708616-1
GAAGGTCCTCTGCACAAGAGCGACAACTGAGAACCCACCGCTCAATCCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCAGG
+
DCHFIHAADE?FHGB@I?@CFFE$ICFFFB@CIGCFDCFA?@?@C;D?IBEB@C@@GGHAHCAB?B?CEAGE??HADCADEEB?HHCBC?CB?EHA??AC
@>chr21:9708417-9708616-2
GAAGGTCCTCTGCACAAGAGCGAGACCTGAGAACCCACCGCTCAACCCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCAGG
+
@FBE?CBDBIEI??CDE?IEBCF@I7CE@E@AEG?A@ID@EFG>@?GHGEHIG?I@IC@EBAEICHG@ACCD@GFBHCAG@BHAHEIFAG?HIGDGBEID
@>chr21:9708417-9708616-3
GAAGGTCCTCAGCTCGGGTGCCCAGGCAGTCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCATGCC
+
BIIFFC?HAI?IEI@DGBA?DHHIDHIBF.HIGFABEFADFCBHH?CBEA?FEGHBHEGAHCHGDFEGDCBGFFI?GGC?CBHABACFII?EGIHHEEIG
@>chr21:9708417-9708616-4
GAAGGTCCTCAGCTCGGGTGCGCAGGGAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGNGCGCCAAGCCTGAGGGCCCCCAGGCCATGCC
+
@D@FHIEBFCDAFGBF@CDAE)HIG@0A@CDBAAGDCCBIDEF?DGFE?HAB?A@CCBFCEFGACGEE6?CHGACGDDCAH?BEBE?D@CDEEGHEEDBC
@>chr21:9708417-9708616-5
GAAGGTCCTCAGCTCGGGTGCCGAGGCAGGCTGNAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCACCCAGGCCATGCC
+
A?DDIF?BFFFBBEBB@IFICB<IDEID@CGCE*GIIAFGBHGFCA@@@EIDHEHDIEHFCFA@H@DBAEAI@DFCHG?BAAC?HA(AHDFEAD@IFEIA
@>chr21:9708417-9708616-0
GCGGCGTACNGCCCAAGAGCGAGAACTGAGAACCCACCGCTCAACCCCACACGAGGTGACTGCCGAGTGCGCATATAAACGGCTCCGATCTCCCTCAGGT
+
EAFHCG@C?*A@DHGIIHA@EECHFEGHH@DA?IE@@BBBCCG@C?D@D@DIFBAEDG?D?I?F?HAAF?-EIIBEF@@B@CB?C?ICG@IGCGB?AC@B
@>chr21:9708417-9708616-1
GCGGCGTACTGCCCAAGCGCGAGAACTGAAAACCCACCGCTCAAGCCCACACGAAGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTCAGGT
+
B?GICB@BEH?IGHCGE2?AEBIEGCDCD>CH@B@CGBCDFACF%?I$GA@BBD!EC@ACACEF?ABFEB?DI@GGGHE,EADI?AE@EG?F?@IDGHDA
@>chr21:9708417-9708616-2
GCGGCGTACTGCCCAAGAGCGAGAACTGAGAACCCACCGCTCAACCCCACACGAGGTGACTGCCGAGTGCCCTTATAAACGGCTCCCATCTCNCTCAGGT
+
@C?I@IGBDBEI@CABDI?IBFCD@IAFBDEFAEAIHCBEHEHA?CDAGH@BE@ADGFEGFIDCFFDCFHFD!HCIFHHHA??FB?4AHI?A;CCIIBCH
@>chr21:9708417-9708616-3
GCGGCGTACAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATGGCCNGGTCGGCTTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCATGCCT
+
B??FAIGG@FAEE@HIFDHD@HBGBHHCCA?IDGFFFII@HEHD@)FAIIHFI=GC?DAGGDBFBEAEFD@FI@CEAEFEE@?GCA@HG?A?G@H@@CIA
@>chr21:9708417-9708616-4
GCGGCGTACAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGTTCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCCTGCCT
+
AFCHAGD?C?H?GEDCEB?GFFC?BDEBBAFCFGECCC@DFGG?@C?FCC??FDAGB?E;CIDBF?DA?AEGAHDHDEADGIEA@HGIEEEE?D+FHD@C
@>chr21:9708417-9708616-5
GCGGCCTACAGCTCGGGAGCCCAGGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCATGCCT
+
IFBAH$CCEDDDFIIC@0BFFABIDHCHDHFACHFCIIIBEIABFH?GEF@CDBI@EEG@GC@CAAH?FH?IAAEDEABBAEGGC@FFH?@@FCBBG?GI
@>chr21:9708417-9708616-0
TCAGACGGTAATCTGCCCAAGAGCGAGAACTTAGAACCCACCGCTCAACCCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTC
+
EFECG@?HG?HEHAH?GGG@CBCC<G??GEA2AFFAHIAFFEIBCGG??GHICEBBDIE@HHI@CIDH@HGBII@@BEDAABG@IFCFHFEB@HGAFDHF
@>chr21:9708417-9708616-1
TCAGACGGTAATCTGCACAAGAGCGAGAACTGAGAACCCACCGCTCAACCCCCCACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTC
+
E?IGFGBGDG?D(@IIECEBHG?DCGHICCEAHFA?A??@G?CE?DBDAECC6I?EF?FCH@??HAIADDICICGHA?DBF?AA@DD@GDIFIA@@AB?E
@>chr21:9708417-9708616-2
TCAGACGGGAATCTGCACAAGAGCGAGAACTGAGAACCCACCGCTCAACNCCACACGAGGTGACTGCCGAGTGCCCATATAAACGGCTCCGATCTCCCTC
+
BAAHFBHF'HHGAFBGBEIF@BI?GAA@?CC@BHCBCHFIBE@IC?FHI.HECGEDBAA?GCEEIIH@GFGDIDIEBBBEE@DCH?FC?HH@BHCIA@HE
@>chr21:9708417-9708616-3
TCAGACGGTAAACAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCAT
+
BAAFA??@CF@8CAG?FAHGDIBFCHI?EF@BCAGBCFC?DE?HCDDEC?FIICIIE@GDAI@FHACGFD?GEE@FBEBBH?CCBGGEHGBDE?HBII@?
@>chr21:9708417-9708616-4
TCAGACGGTAATCAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATCGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAAGCCTGAGGGCCCCCAGGCCAT
+
B?HFG?GHHAEEBEAFDE@E@FH@BHCBHH?@EADEHE@HAC?EB)I@GAA?BB@HGGA@HFDC@@EB?EFICF@DCFGFHEBEII?IECFCHHGBHAGE
@>chr21:9708417-9708616-5
TCAGACGGTAATCAGCTCGGGTGCCCAGGCAGGCTGGAGGTGCATGGCCTGGTCGGCCTTGGGATCGCCAGCGCGCCAGGCCTGAGGGCCCCCAGGCCAT
+
AEBGH?CCFIHE@IG@GBBG?C@@BI?D?BDFDI??HEIADDBGFDI?CIEIDGC@?FIGIA?AGDDBHBIHFBGBIF#A?D?FFAGFFHHAIDD?FIGD
@>chr21:9708637-9708742-0
ACCACTATGTCAGCACCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCCGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAGN
+
FDAGCEAGGCGCCCDCFICCB?F@B@CGA?DAHE@A?BBGDECGDAC?CGE@?HCBB?ICIABE>HDC@ABE?ABHACFIGGF?GE@HF?DHA??EC@F"
@>chr21:9708637-9708742-1
ACCACTATGTCAGCCGCCTCCAGGCAACTCCCGAGCCGGCCCACACTCCCCACATCTTGNAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAGG
+
?HBEBCBE@??CEE1HHCGFGGHADI?HEEFHBFGFG4?BBCE??IBHHG?EF?AB@G?0EADADID@BHCFAFEFGIACH@CFG@HIIGH?BFGDGDFC
@>chr21:9708637-9708742-2
ACCACTATGTCAGCAGCCTCCAGGCAACCCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAGG
+
GFDCFGCCC?DFG;DAADHDGE?AF@?G0+BDBHD?DIFIBCI@AD@I@=?FIDFDFFB?HI?GE@G?AHBGEDE?FCHEEDBC@@I?BCGFCHEDIEHD
@>chr21:9708637-9708742-3
ACCACTATGTCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGTT
+
ID?IADBEAF?CHBHCGIDDFBIDHHGEDD@FBBCIBH?BCBFCCHEH?AFC@F@?E@GGCEGIAFF@?A?DDCCCGA?BDGIB@HDFEGA?CAG@HADD
@>chr21:9708637-9708742-4
ACNACTATGTCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGTT
+
AE<C?EADDC@D@AB@EBEBDEDDIGBHFHC@AGGCBIFEFHBI?CCFGIEA?B?BGHEC?FEEB??AC?CCIHEG?GC?B@BFIHHBBCB?CGHHGADE
@>chr21:9708637-9708742-5
ACCACTATGTCTGCAGTACAGACCGCCTGGCATGGCCACAGCCACAGGGACATTTGGCCCTGCTTCCAAGATGTGNGGAGTGTGGGCGGGCTCGGGAGTT
+
FDACE?GCAICAEAED@DFDBFBCDIIBDDD$@FGHA@@DHHA@E?D@EGIBFHAFEDEA?3AIGF?BE?AGCE?$CAEIACFBBABAFIGCGB?CD?CF
@>chr21:9708637-9708742-0
CTCATACCACGCAGCACCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAG
+
BIGHBCFEBBIIHBFGH?G@DFGI?BGI?CCGH@GHHE?CDFHHEH?G?ECGIGAHBECCGCEABDEGFEAA@?B@?GCEF@DBCDID?E@?HE?GGDBA
@>chr21:9708637-9708742-1
CTCATACCACGCAGCAGCCTCCAGGGAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGACAG
+
@AGCHG@C@HB?GBA@C@CBGEGHD3BI?A@ADCG?@DHHFFIA@C??GADFHFBGF@HB@?IBFEE@@DEBHGDDGGG@AABHCECGDGCCEABD,DD@
@>chr21:9708637-9708742-2
CTCATACCACGCAGCAGCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAG
+
AE@?GF@FGEIA?ACHDEFIGIFICB@CFIE?@DA7HB??A@HBFEDB@@HBFDACADHH?@AEADEIDBEEBII@IFA@FGGAFIEBE?EECEAI?FH?
@>chr21:9708637-9708742-3
CTCATACCACGCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGT
+
HEEB@@CH@IGDD@DBABHAG??AFAFGGHCF??@IHA?CCEGA?@B@DDGF?BCFDIDHDHH@?HIDBEDHECAC?CG?FI@AGDHB@ECFEHB?IGIE
@>chr21:9708637-9708742-4
CTCATACCACGCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGACCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGG
+
IE@HD?FHDACAAGEAAD@CEGB@BHC@IGCCCICBGE@CA?AAIF@BFIAEH@EFDF$FEFBCBACDAHG@@FHCFGGGIG?I?DEF@?AF?BBG?BB3
@>chr21:9708637-9708742-5
CTCATACCACGCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCAAAGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCGCGGGAGT
+
BGHD?EABH@CBE@@CHFAGDCGAHHFIDCAGHC??AD?AAIHBC=?IAFBABGED?AFFAIGACIAAFC@EE@FHHG?HIHGB@EH@DAEB;I?BAECF
@>chr21:9708637-9708742-0
GAAGGTCCTCAGCAGCCTCCAGGCAACTCCCGAGCACGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAGGC
+
?@CH?BCC?DD?BHIIGAFG@HIGF@@FCFF?B@I#@DGEF?DFDCEIGDH@CB@BH@?FB@CADDACCCF?DG@HAA??DIABCBFEEFHCE?H?ADBG
@>chr21:9708637-9708742-1
GAAGGTCCTCAGCAGCCTCCAGGCAACTCCCGAGCCCGNCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAGGC
+
?FIDDCFCCEFCDDDEB??FAEFH@CFIBFBBGFCFDF3EACFCHA@@DGBE@DBCCBCDD@CEAGF@CFBAIIHHAEBE?GG@D@HHIGCC?GH?AGHE
@>chr21:9708637-9708742-2
GAAGGTCCTCAGCAGCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAGGC
+
IBFIDGIBEFCC@EBCGG@D?CDB@@HCE@GBFEFF@HCCFI@HHD@DFDGEDEFD@?HA@BAIFG?BF@HEI?DBFDB@@BF@I?DEE?DBGAHHHD@B
@>chr21:9708637-9708742-3
GAAGGTCCTCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGTTG
+
EIEFF@CBB?H?AFAHHDB?ACBFHFEE@?EFBDEFF?GDGIBHCIDC@HAHIH?CD@FB?H?F@@C@EDAIAD@HAFCDGGAI?H@IBEBBGIAFHIDF
@>chr21:9708637-9708742-4
GAAGGTCCTCTGCANNACAGACCGCCTGGCTTGGCCACAGCCACTGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGTTG
+
EGFIEBA?ED?DAB;8?ECF?EIGIABBBBEB@E?A@GIBC@?H$F@FIH?EAG@BDA@@BDCAEBCHAF?HCHDHAIF?B?BCGEDBAIBIGC#DCBDB
@>chr21:9708637-9708742-5
GAAGGTCCTCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGTTG
+
DID?ADDECAIDAGBABEG@@BE?GGEFIED@II?H@A?H?A?C@IFG@?BIEAFBFAAAACEFDI@@HBDBEF@D@HIIBCGEE?IGHIEHDBF?EDE@
@>chr21:9708637-9708742-0
GCGGCGTACAGCACCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACATNTTGGAAACAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCAGGCG
+
BIABEFCIABDC?@GG@CHEBGDGHAAD@DI?C?CDIBFCACI?FG@IFDCAG>HB@HEE8IIGFGH?@@E@GHBBCHF?C@?DEIF@@DGD@ABBDABG
@>chr21:9708637-9708742-1
GAGGCGTACTGCAGCCTCCAGGAAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCCGTGGCCGAGCCAGGCG
+
@#DH?BA@E8?CIBIEAHIGAD+?F@ABHBHAC?BFAACIIGHHCED@AGB@FHICBCCIG@(?IH@GDAECI?HFFECHFIE9DDCCFD2AEGAECGHD
@>chr21:9708637-9708742-2
GCGGCGTACAGCCGCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACANCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCNAGCCAGGCG
+
ABEFDCCD?E@D5BCEAG@ECDHHEDDECEEIGDAFCCHEAHDD@IHIE@AI<GDI?GCICEBHBBI?'@DBC?B@DC?A@FHF?FBGDH1IEEDEC@?H
@>chr21:9708637-9708742-3
GCGGCGTACTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGTTGC
+
HBHGFB?@F@DGCBGABABGDCEGFAAA@?@AGGFBGCBIEGIC?GA@DBGA?@BHBA?AHCDDEAAFCHECG@B?HE@HGF?CFAAFF?HFCABG@BCG
@>chr21:9708637-9708742-4
GCGGCGTACTGCAGTACAGACCGCCTGGCTTGGCCACAGACACAGGGACATTTGGCCCTGCTTCNAAGATGTGGGGAGTGTGGGCGGGCTCGGGAGTTGC
+
E?A?A@FCHADFDHIGAF@?AA?FHGHFACICE?@HBDE<GECG@IFEAFACF@AGCHIHGFBA/EHGGEGGDHDFGG?E?HHHAFIAGIHHGDD@DBA?
@>chr21:9708637-9708742-5
GCGGCGTACTTCAGTNCAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTCGGCCCTNCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGAGAGTTGC
+
C??@?CAHBG4A@??6?CDBHAADF@?ABEEGGBCED?D?I?HAC@IDDF?A0C?F?G@+EDDEGHFEEBCFA@HEFEBCIF@DCHHF@@H?)AHA?D?D
@>chr21:9708637-9708742-0
TCAGACGGTAATCAGCACCCTCCCGGCAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCA
+
GGGCCDIFEGHHIAEFED@G?HG6EEBEB@@GBGGBCCIGDG5DFDHFF@H?GB??@E@CCAEHAHCBAE?I?E@HDFIH?D@F@A?B??CCHHIH@?DA
@>chr21:9708637-9708742-1
TCAGACGGTAATCAGCACCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCCAGCCA
+
AAECF@FAIE@HDGBHCFDFBCCA@CAEB?AIA?BE?IAFI@H?BDFA@CBBGAIHHI?BADAE@AHGFBD?A@AA?FB@BBEICEG@AFHBEC:@HB@G
@>chr21:9708637-9708742-2
TCAGACGGTAATCAGCACCCTCCAGGCAACTCCCGAGCCCGCCCACACTCCCCACATCTTGGAAGCAGGGCCAAATGTCCCTGTGGCTGTGGCCAAGCCA
+
GEICBAFIDBGEIDCFFIIABGHAHIFCBGAHI?CF@F??IEI?CI@?EEAEG@HIAEG@CFDEFIHDHDE?DCDIDC?GFHDCCACD@AFG?DBDHG?I
@>chr21:9708637-9708742-3
TCAGACGGTAATCTGCAGTACAGACCACCTGGCTTGGNCACAGCCACAGGGACGTTTGGCCCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAG
+
C?BAIA?A@EGI??CAAI?ADFIBAB%GE@E@BEDCE,?B@FBIICBIFBDFA%F?@GF@HD?IICI?AFDICGI@@B@IDGECEE@DEHA?IDCCH?>H
@>chr21:9708637-9708742-4
TCAGACGGTAATCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGCCCTGATTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGGAG
+
F?H?FBIHB@BAI@GBGIEFGACCBIGCAEB@E?BEEACFGFHE?@GDEDH?HBBCDB@AGCAH1?DCFGA@?DBHIC??CIBHFDE@CBH@?HIIF@F?
@>chr21:9708637-9708742-5
TCAGACGGTAATCTGCAGTACAGACCGCCTGGCTTGGCCACAGCCACAGGGACATTTGGACCTGCTTCCAAGATGTGGGGAGTGTGGGCGGGCTCGGNAG
+
F?BH?FBGDF@H??HFH@E@EH@?DFAACBEI@?@IEBA@AI?GGBGDIFAABCFAEF@6BDGIBA?A?IE@EDAGEGGHF?DCFEF?HDABEEHDB.AA
@>chr21:9710852-9711000-0
ACACCTATGTCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATTTTTTATATGTTGAACCACCCTTGCATT
+
BF,4IH@DFI?HFGBABEAI@.AADBDEHBD??F@B?BFC?C?EF?FH?HAGDAB@@AGGD?CGBHFI@?A?AEC?CDG@?CF@AC?FFDBAGIIHAACC
@>chr21:9710852-9711000-1
ACCACTATGTCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATTTTTTATATNTTGAACCACCCTTGCATT
+
AEFA@H@?IEAGEEIBBIAEB@CGDGBCGFEEBG?AI@DEC@CDFFABDFEGF@CGEIFD?GGCEIGBHGCGA?IAIDDAH7CCEI@H?@?CIIHEEGCG
@>chr21:9710852-9711000-2
ACCACTATGTCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATAACACTGATTGATTTTTTATATGTNGAACCACCCTTGCATT
+
A@HIGFDA@IAI@D?@H?@EEBCA?@FFGHAHHFEHIGAID@IGAE?CG@@@CFF?CFE2?DHAABFFGFE??I?HG?FD??A/@DABDI?HGG@GBGGB
@>chr21:9710852-9711000-3
ACCACTATGTCAGCAATACTGTATACTCAAAGGATTGTAAACTATCACCCTTTGACATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATCA
+
EICC?AC?F?@H@DFCEIGDBBA@A8A@GII@BAEIBGGIHDIIECCA?@$CBHD4IIDI@DEFFECE?F/FHGBADDDGEEEEBI?CEAI@E?HGC@HA
@>chr21:9710852-9711000-4
ACCACTATGTCAGCAATACTGTCTAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATCA
+
EHHDHHAEG?EGGGIEDHHH@G(DAC@E@IDB@GE@BBE??AFGHC@AIIHFFBDGBF?@H@DG?B?BDE?EDCHAIEEDACBDBIIIFDCDBHHF??AD
@>chr21:9710852-9711000-5
ACCACTATGTCAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATCA
+
@@ACAIHDEGDIBAIFCHIFG?HDFIEHACCDIGCCHCEAG@@@GF@GAAGDD@@GDG@?G@@FDIHEGEFHGHABDE?FBIBIHBCDGDG@AF@FFEED
@>chr21:9710852-9711000-0
CTCATACCATGCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTNATTGATTTTTTATATGTTGAACCACCCTTGCAT
+
C?BHIGBH?)DD@@EEFHBF@EHDGBAI?EEHHG@CED?F@DCFFBAFFIBCCEI?FIAEIE@IFD*I!CG?GH@HGBCF@H?GFDB?FGHBEHFDAA@?
@>chr21:9710852-9711000-1
CTCATACCACGCAGCAACTGAAATAATCATGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATTTTTNATATGTTGAACCACCCTTGCAT
+
HBCAAA?@@CEI@@DHD8FBAIHAHFAHI:@DHEDA?CHB?D?BCAEGCCFGCDB@EAA@GBI?CGADICE?AAIIB+I@@@I@CCGIBDG@??CG?ICH
@>chr21:9710852-9711000-2
CTCATACCACGCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGTATATTACACTGATTGATTTTTTATATGTTGAACCACCCTTGCAT
+
EACEGHC?CIG@AGAIA?FDGBDGDBBDCE@BIAHGGFEDEGI?CICIBA@H??H8A@GABBIAIEGFE@CFIFA?HAG@ABE?EBD@D?FFHEG?FIDE
@>chr21:9710852-9711000-3
CTCATACCCCGCAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATC
+
AGCFEGHD5IAIEDGDH??E?HAECC?HE?FD?FCC@EGBEF?CGAB??GFE?@?BAICAH?EBHFACGCBFI@C@EB@AICI?DD?IGABIBAFEHDAI
@>chr21:9710852-9711000-4
CTCATACCACGCAGCAATACTGGATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTNTCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATC
+
FDI?BEIEHFDA@HBICABBGH5?A@EGH?HGHB@?ACIIHHHCHAEEAA?HAGDCG??HB%B?DBEDG@FGB??FCAHCIFEDIEAIDGCCGCEC@HHF
@>chr21:9710852-9711000-5
CTCATANCACGCAGNAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCACAATGCAAGGGTGGTTCAACATATAAAAAATC
+
@BEB@A2CEIBCGC)CIC@H@H??E?CACCD@?IDFI@HBBHAGAHDF.BECHCGHCHIHEC>BC@FH:@GIH?@HBGI@GCHBG@AGE?@B@BFAAC5D
@>chr21:9710852-9711000-0
GAAGGTCCTCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATTTTTTATATGTTGAACCACCCTTGCNTTT
+
D?DEBFAB?GIIC?AFCCBAB?IIF?CDBEIDADB?ADA?CAC@HF@EFEEBEH@EGGHAC@IBAABGEAA?B@AC@FEGDH?@EEDIABGGCB?C9CHH
@>chr21:9710852-9711000-1
GAAGGTCCTCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATNGATTTTTTATATGTTGAACCACCCTTGCATTT
+
?@BBE@CFEEABFG@GADH?ACIC@FAAGD?CIFG@AAD@ACBHGHIFBIAB@IGCHFBBHAC?DD?$IDIEFHD@HGIFH@G?I@A@?BDDCIDDFHII
@>chr21:9710852-9711000-2
GAAGGTCCTCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATGTTTTATATGTTGAACCACCCTTGCATTT
+
GBCEFFEIGGFD?EEDBACIGFBH@CDCBDGIGGCHBBB@IID@IE?@EI?@GFE?AGHIGFBEBDF@AB?'BFGDBH@IFBABHADAHCI?EII?DAAB
@>chr21:9710852-9711000-3
GAAGGTCCTCAGCAATACTGTATAATCAAAGGATTGTAAACTATNACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATCAA
+
II@DEGAFAFF@ACDDE@ECEH@F??AH@H@GEGAHED@AICIG<DFDIDHGFEAGHFI@?CGED9EHA@EFBBHHDEBHFBC@EI@?CFAEAFDD)AC?
@>chr21:9710852-9711000-4
GAAGGTCCTCAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATCAA
+
AFADIIFCFCAG@BEHF@BFF@DFFBABG?GDF??I@GBAA@EFBCB@DDIEGHHAEHH?G@CAGAGD@H?DFEE?IEHEBGDCDHB@CGDFIBICA@@F
@>chr21:9710852-9711000-5
GAAGGTCCTCAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCTAAATGCAAGGGTGGTTCAACATATAAAAAATCAA
+
E@BAA@GD?F@GFBB?GDBAG?DBCCI?DHD?HG?BEI@GAIEGDFAB@AHHI?@GBBBEG@GGB&HDFHI?H?DGCGFEFAEBE@CIDCHHCGGIFG?D
@>chr21:9710852-9711000-0
GCGGCGTACACCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATTTCTTATATGTTGAACCACCCTTGCATTTT
+
HDIFGE@BCI%HHHE?HAFCBAEFCCAEECDFBGAHAIGFCD?H@EDE?IIAGA?G?BFFHG@EHEIECIFADG@GE@B?DFAB@HIIDB@BHHAE@B@H
@>chr21:9710852-9711000-1
GCGGCGTACAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATTTTTTATATTTTGAACCACCCTTGCATTTT
+
@FBFFACDI?E?HHHHAA@@DGBDFE?DAAIGIDCI4HIAABIFFGBIDCGDBHCCA?EGAD?IAAIECCCB?@BHIFB$AHBGG?IFDBEBCD@DAEHF
@>chr21:9710852-9711000-2
GCGGCGTACAGCAATTGAAATAATCACGTGCTTATTGATTTTACTGTTACAGCACATTACACTGATTGATTTTTTATATGTTGAACCACCCTTGCATTTT
+
BAC@???@DHFIIAI@@CGGA@D@I@AD?D@CHGHG>D?HDAA?BAEEBIIF@B4?FDG@AFAF@AGCFHIGBH@EFAIE?FG?GHEDIBHABBI?BEI@
@>chr21:9710852-9711000-3
GCGGCGTACAGCAATACTGTAAAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAAAAATCAAT
+
@BBC@IGCHCFGHHFBIEEC@1AF?GEIIFEGAFAAHF@?C/?@CCEEBFGH@GFBBA?@F?@EIIIBDF@CB?CGC@I?@GFGHAIHHDBE?IFFEHCI
@>chr21:9710852-9711000-4
GCGGCGTACATCAATACTGTATAATCAAAGGATTGTAAACTAACACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAGAAATCAAT
+
@?@BHF?BDD6G@!GEDEHFDEDFFEGDGIEHHI@E@D@IF@/DBBEB??CG@CGHD@CFAA@AEA?@AFEA@EFGFIDIB@FE@I@DHGF?EBC?I?HH
@>chr21:9710852-9711000-5
GCGGCGTACAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATACAAGAAATCAAT
+
ECI?C@DFEHDC?DFH?HFBH@HIBEG@ABEIBHG@DEIED?DGG?A@F@AEFIBBF?GCHAAHAAHCHGAE?CCDIIIIF?B@GFBH:BDC@DH@GGH?
@>chr21:9710852-9711000-0
TCAGACGGTAATCNGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCGTATTACACTGATTGATTTCTTATATGTTGAACCACCCTTGCA
+
C@CAAHDF@HAFB&EGCBIB@H@FGEEHGBID@B@EHH@A@I@DFECH?EIEDBEAH2GD?CDDHAF?@ADFCA?FG?@HDDGFFF?EDCBG?AI@?F@G
@>chr21:9710852-9711000-1
TCAGACGGTAATCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACACTGATTGATTTCTTATATGTTGAACCACCCTTGCA
+
BDEEEDBGHEIDCFFDFGC@FID@BGFIFIG?HA?A@GG@CCCCDDDEACH?@A@A@GG@IAD?BHGHIEF?ACFAHIHDEG@AEAH@@FAAFGHDAGEA
@>chr21:9710852-9711000-2
TCAGACGGTAATCAGCAATTGAAATAATCACGTGCTTATTCATTTTACTGTTACAGCATATTACNCTGATTGATTTCGTATATGTTGAACCACCCTTGCA
+
IED?AHCBEED@I?GGB@?HC?FIIIA@HACBFH?B@IDBA?B?HDEI?H?E@HIAHHHF@BFH/EAGDEGFECCHH7F?DEDCIDDFCAIDAAF?DGBA
@>chr21:9710852-9711000-3
TCAGACGGTAACCAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCACCATATAAGAAAT
+
EC@BDG@HBFB)ABEH@AGGDHBFH@HCCIAFIAF@EBIGCAI@HB?HIA@?GBA@?EFCBBHI?HIAD?@FDE?HFCCHIDA?FDA:?FCCAB@DB@BI
@>chr21:9710852-9711000-4
TCAGACGGTAATCAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAGAAAT
+
DADIHHBEHCCGHA?GDCBACDABBFEAE?C@C@FH@?HFACAHIFD@DEGGFAAGFGHEEB@FHHAF?CH??DC@?D@C?EIBCDD?FDGIADEAHHFC
@>chr21:9710852-9711000-5
TCAGACGGTAATCAGCAATACTGTATAATCAAAGGATTGTAAACTATCACCCTTTGAGATTTATCCCCAAAATGCAAGGGTGGTTCAACATATAAGAAAT
+
CEHG?BBAEHCBHGBGHCF?C?II@FCICC@A?BH@ADIGBF??EEGFHICBEFFCBEG?AACBIAD?@BDIB@FIEE?E@?DFECI@IICCCIDC?CBI
@>chr21:9712420-9712541-0
ACCACTATGTCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTNTTTTGGGTATANACGCTTAAAGGGCGTTGATGGATCATA
+
IAHCDFI@?B?CI@?HI@GI?GACIGGFIFGAADB@@BG?IFD?EEGCIBH@DAGGGECF!ADI?FB?@EEG"FHBII?FCGIB?/IG?GDHEB?F?FI@
@>chr21:9712420-9712541-1
ACCACTATGTCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCATA
+
CD@?FGFIEBFDCDCDEBAAC?FCAD@D??@ABAIHCFAB?DB@DCI?C@DDGAFB@AG?@A@@DEH?EH?@FCEHB?@@FCDA@EFGIEDEBBD@DDA?
@>chr21:9712420-9712541-2
ACCACTATGTCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGNCCCTGCTCTCAGTTCTTTNGGGTATATACGCTTAAATGGTGTTGATGGATCATA
+
DB?AHH@CHICEHGBIDHFCEGDIGFI?CIBIHAD@BC?C@ECBF8CBACIF@AFBDEED?FEG-BGBHCDCBDIG?GGHBD+?BECAFBBGG?DFE?FG
@>chr21:9712420-9712541-3
ACCACTATGTCNGCTCCTTAAAAATATGAAGCATAGATTTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGAGAGCATGGACTCA
+
E?ICGHIEEBB+H?GC?EIBH?IAEGCFHAHIC@E@C4BGEHAE??CDAGACI@HBEG?ICIF@GFCFHE?IDEGFEADB?@AEIA@F@IBE9FBCHCDB
@>chr21:9712420-9712541-4
ACCACTATGTCAGCTCGTTAAAGATATGAAGCATAGAAGTATCTGATCCATCAACACCCTTTAAGCGTATAGACCCAAAAGAACTGAGAGCAGGGACTCA
+
C@EAH?HFGHI@?BAB>GAHGGIEBDBH@@GC@D@BI?=9CA!IGHIBFAABE@HH@AGCDFF?BDA@G?D:IEHC@@EBFIG@?EBCAEI?AHG?DCFB
@>chr21:9712420-9712541-5
ACCACTATGTCAGCTCCTTAAAGATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGAGAGCAGGGACTCA
+
CCGH?EGGIGAGDB@?BB@IDGIDFEA?ECHBE@DFFCDD?DFIE@FF@BI@@EHBDBCCA?CHC?C@ACCAEG?IFGD?@#EEHCABDAB@BIBAFIDA
@>chr21:9712420-9712541-0
CTAATACCACGCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTCAAGGGTGTTGATGGATCAT
+
@G(A@H?EAA@DDIGEB?GGA@C@D?E@GA?CDI@GFB?HEDD@AA@D??C?FFCABE?ADII@EH@?GG@?GDCIBAC@6DHBA?GGACHFGDGGBA?F
@>chr21:9712420-9712541-1
CTCATACCACGCTGCTGTTAATCCGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCAT
+
D?BBGFDDAHAHFG@FCD?@H?G-F?DFCFB@DEDH@?A@EBDE@HBEHCFCEB@FG?EBDAEBE?FDCGDDD@CDGGBI?IBC??EDEA@I@B@HAAFG
@>chr21:9712420-9712541-2
CTCATACCACGCTGCTGTCAATCGGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTCTATTGGGTATGTACGCTTAAAGGGTGTTGATGGATCAT
+
H?H??E@DDAGHCADGHE<BEIDIA@BCEDEAIFGIH@EICD@AHAGFGDEAFFEEDH%CB@I7GEDC@E?@0G@GHCHIDDA@IDCGIGDEGFGIFIFG
@>chr21:9712420-9712541-3
CTCATACCACGCAACTCCTTAAAAATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATTTACCCAAAAGAACTGAGAGCAGGGACTC
+
?@CA?FA??CGEA.HE@FACDGGIED@EA?I?GIBCH(?DACDAGFBIB?DIB?EHFBBIGB?DAHDEBBB1IAHFCGB@ID@AI@HG?EGBDDIAI?HH
@>chr21:9712420-9712541-4
CTCATACCACGCAGCTCCTTAGAAGTATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATACACCCAAAAGAACTGACAGCAGGGACTC
+
?AG@I@EIACFC@FH,DB?GI+BB'BE?ICCCAGBHHFIBAGGCBDD?I@@BEDEEABFFDCGCCGGBDGHE$HGD?BGADEHHGFGA+AE?I@?IIEIC
@>chr21:9712420-9712541-5
CTCATACCACGCAGCTCCTTAAAAATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGAGAGCAGGGACTC
+
FDBGHGAFDHIGDG@EADE?EFC@G@AFGE??FGI@BFECGFADEAED?ABGBBCEFCHA@?IA?CEHAH?D?DB@CBFBBDGCEFFFAAICFE-IDDCA
@>chr21:9712420-9712541-0
GAAGGTCCTCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCTTCTCTCAGTTCTTTTGGGTGTATACGCTTAAAGGTTGTTGATGGATCATAT
+
HEAEGDEI@BHBHCG?FD?GIEDA???GGGC?HC@AEF?GAH5E@?AFE9ACHHE?GDAHEDAFFEF?+FBD@ABCEBIADHH,HH?E?DGFCBDHEEIE
@>chr21:9712420-9712541-1
GAAGGTCCTCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCNGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCATAT
+
EH@G@HD?C8?G@GAFCHBHHAHHI@EAFH@??EFGBEH?IIDICCA@.CBDDCA%HD?@I@HF?DG?C@?IHCBBGEHHAADIGCAIGEAEC@FGHFAI
@>chr21:9712420-9712541-2
GAAGGTCCTCTACTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCATAT
+
FF?CDEEEDE@+@DFC?@@GIEG@HADH?C?HEEEIADDI?CFHHCCAAGDDEFDBFICCAFBDHHEDE@A?B?@IEHCGEEB@IICFIECBA??EFIHA
@>chr21:9712420-9712541-3
GAAGGTCCACAGCTCCTTAAAGATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGAGAGCAGGGACTCAA
+
DBGG@BEH/DFFBFBBFGFIFH@IIG@EAFG@@AFBGAA@@@CEGA?FEBH?@AB?DBC@FCEICHEH@GHED?EHCHECBBDEA@AFHCBEGH@EHAB@
@>chr21:9712420-9712541-4
GAAGGTCCTCAACTCCTTAAAGATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGANAGCAGGGACTCAA
+
?HABD?CC@HG8CAF@DIG@HEEA?ICABAIHBIF@CBIC?CIC?IE@C@IGGE?IGDEIEH@FC@D@DHFCI?F+DAD?GAG??G/?CGE@E?ADC?C?
@>chr21:9712420-9712541-5
GAAGGTCCTCAGCTCCTTAAAGATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGAGAGCAGGNACTCAA
+
D@HEIIABGIBCEBHB?EDAICCFGCH?GBGCAG@IAEFECFAABCFFHH?FDFGGI?ICAIBIIA@HC??E?BF?IECGEEIGD@I;?FIC?!I@HE@H
@>chr21:9712420-9712541-0
GCGGCGTACTGCTGTTAANCGGGTGTNGAAAAACCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATCGATCATATA
+
?CBDGID@FBHIEHE?E?9A@GAI@E74DAA2?EFHHG@AA@GEFHGABCHIG?FF@FEEBBIC?EB?DA@CEHHFB@BCFDIIC@?AEC%IFED@FBEF
@>chr21:9712420-9712541-1
GCGGTGTACTGCTGTTAATCGGGTGTACAAATAGCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCATATA
+
IIEA*HB@GIDGBBH@CA?GAII@CCEAICIEC+?DE@H@D?HHGBDI?BH@HACHIADHAIC@D@BD@E?DIH@F?FA?EHD?BGGEAGIH@?@@?DEC
@>chr21:9712420-9712541-2
GCGGCGTACTGCTGTTAATCGGGTGTACAAATAACTGTTTGAGACCCTGCTCTCGGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCATATA
+
BII@AI??@E@ADDBBC??F@BGF?I?I?FH+B=E?GDCBFIF'IBA@BAI?E@5GBBEDA@GDF?A@E@FIDIIFAI@HH?I?AIBC?IABBDDG@IAA
@>chr21:9712420-9712541-3
GCGNCGTACAGCTCCTTAAAAATATGAAGCATAGAATTCTATGATCCATCAACACCCTTTAAGCGTATATAACCAAAAGAACTGAGAGCAGGGACTCAAA
+
HAA(EFDA@E/FE???GFD??CA?@GF@IADEBDH-GC*@A@BI?CG@IFFA@FDDGIG?B?HGEBEH@DD!GIB?IEE@IFGBAGIGH?HIBCCGIHCG
@>chr21:9712420-9712541-4
GCGGCGTACAGCTCCTTAAAAATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTAAGAGCAGGGACTCAAA
+
GDG@EI?H@IIFGIDA?@E@GAD?AG?DHIBB?E@IAB?FBBCEBHGGFBI@HGBBAC.ADDIBBDIBHIFFGBHF@HAFHIH!@CH?GHEEB?FH?GAD
@>chr21:9712420-9712541-5
GCGGCGTACAGCTCCTTAAAAATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGAAAGCAGGGACTCAAA
+
B@G@@EAEAIHDAAFEAAEHCIGAGIHHFHDHDDDAFG@FFCD?AAEGGACBA@C?B??FC??FIGGIH@CAEEHBCGI#CEEEF*EEFGF???HEF?BG
@>chr21:9712420-9712541-0
TCAGACGGTAATCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCA
+
I@FH?FGHDFBEDEHB??DACEIAD?B?FB?ECGHGHBGHFGDCD@DBIB@HBH@CHDIEAFHBIB?ACIGGGIHC?HE@AIEEIIGHAHD?FHCH@D@@
@>chr21:9712420-9712541-1
TCAGACGGTAATCTGCTGTTAATCGGGTNTACAAATACCTGTTTGAATCCCTGCTCTCAGTTCTTTTGGGTATATACGCTTAAAGGGTGTTGATGGATCA
+
DDFIH@GBEAF?AHCFDGFF?ED?@FGD>CGCFFEFG?AG@FGEEA'EIAB@BDDGD@IGEF@EFGCIGAG@GCIHEFE?FBI@I?@CFBIE@@<HF@E@
@>chr21:9712420-9712541-2
TCAGACGGTAATCTGCTGTTAATCGGGTGTACAAATACCTGTTTGAGTCCCTGCTCTCAGTTCTTTTGGGTATATACACTTAAAGGGTGTTGATGGATCA
+
A@DHADFDCGDCA@B@@BGIGH@FAICDFIIC??DDA?BHBBEDEBFDC?C@GGGA?FCBACEE?G?FHGGEDBDB?7?@DBGAGAG??GHICIFI?@CH
@>chr21:9712420-9712541-3
TCAGACGGTAATCAGCTCCTTAAAGATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGCGTATATACCCAAAAGAACTGAGAGCAGGGACT
+
G@F?H@CB?EFEEIBGAF@?DBFIB?GDEG@HAEEFE?GAGCDGCB@GCHFEHBEIBEAIDDB?A@DAAHBAB@?IIHAFDDHFA?F@EIHCDG@@@I@?
@>chr21:9712420-9712541-4
TCAGACGGTAATCAGCTCCTTAAAGATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAAGGGGATATACCCAAAAGAACTGAGAGCAGGGACT
+
@D?GGCBFBDI@DFFFBF@HDA@EBGDEAGAHDFBBDBA?GFEDHBDCEABI@GEBD@?DGGBEACC#D4HDIFCHADDBIEIHGFF?GF?D@@CACAGG
@>chr21:9712420-9712541-5
TCAGACGGTAATCAGCTCCTTAGAGATATGAAGCATAGAATTATATGATCCATCAACACCCTTTAACCGTATATACCCAAAAGAACTGAGAGCAGGGACN
+
GE@?D?I@HFDBC@BAAIBFGI-EIHD@?CBI@FI?EHD@?@@HA?IGDEGCFCDCCHFEAACDHC'IHC@HAHI?DGHA?B@CGIH?GB@HIIACEAA)
@>chr21:9717746-9717836-0
ACCACTATGTCAGCCAGAGTGACAGANTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTATGCAG
+
ABBAB?DHI@C?BFHI@CCAGGG?@E2?G?ECCFB??DB?DIGE?D?BCIE?G@I@?HBG@HG/?CFGAA@EIGGAHDGIBH?E@AFGCA?EA@?CGFHB
@>chr21:9717746-9717836-1
ACCACTATGGCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTATGCAG
+
BCEBCICFG7GFI@DDHIBCB@IA??CIHCIB@ACCDI@I???ACADGB?ECIHIFHDA?@GDGCCFACBG@GBFDDB?ABAB?FFECC?I@?@GGA?DC
@>chr21:9717746-9717836-2
ACCACTATGTCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTNAAGAAATCCCAGCTCAGAGCAGTCTGTTTGACACTATGCAG
+
@EGDBHAHIEGDIIEEAAFIGIIF?DHDIHIH?G@AIIHE?FIAAABAGHGHHHHCGE/DDB@EE?@+FBDBGGFC@BDGIHB@GICDH4?@C@D@D?@D
@>chr21:9717746-9717836-3
ACCACTATGTCTGCATAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGTCACTCTGGGTG
+
D?D?@IIFCDG?DFAEAC?ADD@EH@ICEII@@EHB@EFHGB?ICGDCGIIFD@GBDIIEFEHDCECGB@EH??IDDEDHF?HDHB?GBEHFGH@@A)FG
@>chr21:9717746-9717836-4
ACCACTATGTCTGCATAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGTCACTCTGGCTG
+
?AE?EDDIHI?IHIHDCBFFCIHIIIACIGFECF?@CDDBID6C?CEHBI@EDDCFHBDII@IDEC@HF@BABCIF@?@FCAICFGDGHCGBAC@DG@IC
@>chr21:9717746-9717836-5
ACCACTATGTCTGCATAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGTCACTCTGGCTG
+
FIFBFAFED?DCBADHI?FAIDB?B??CH?F?@IIAEGCF?GBF?A@FB?HGEI@D?@C?FDFED??CFCBFBC?FFDGDFFBH?EAAD@A@@C@?HCHC
@>chr21:9717746-9717836-0
CTCATACCACGCAGCCATAGTGACAGAGTGAGACCCGGTCTCAGAATATAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTATGCA
+
FBI@@GCEDEC@AI?H@'HDEFGBCHGDEBAF?E@DDFGFIDHA@?FE>BAHFGG@?H@C@BBDCI??B@C@FHBA?FFIEC@EEADBA@@GB2CFCEIA
@>chr21:9717746-9717836-1
CTCATACCACGCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTATGCA
+
CGCEBD?ID?GE?DC?E@FBHCIDBFH?BCDCCDCH?HCAI@CE@FBE(@DCC@BAICA?IF@?IED@?@@?BABGAAAGGI@BGGDDG@ADDBDH??@@
@>chr21:9717746-9717836-2
CTCATACCACGCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACANNTACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTATGCA
+
?GDBDGBADDCIC?HA@IGBCH@?AB@HG?FBCI?A@@B?CGGHBIIADA8!EH@DGE@EIFFFG@CHBB?EDGHHDFHFH@DD?IICCF@FFGEDAED?
@>chr21:9717746-9717836-3
CTCATACCACGCTGCATAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATNCTGAGACCGGGTCTCACTCTGTCACTCTGGCT
+
@DEA@@FDDGFDEAFE@FIHGFGHECIC@FDABA@FAB@FECE@GCCAFBBC?FDCFEED@GCDIE?,FA?FB@AIAHIGB@AHF?FED@F@CAEF@AAC
@>chr21:9717746-9717836-4
CTCATACCACGCTGCATAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTATATCTGTACTCTGAGCCCGGGTCTCACTCTGTCACTCTGGCT
+
?GHHGAEF@CHCIAEBIFAC@?GBI?AAFEHE@G?IBI?BECFB?DH?EFFBEIDIC5I0H@@GFG2IFIC?C*AACDBI@BFIGEHBBCIC@BBG@CC?
@>chr21:9717746-9717836-5
ATCATACCACGCTGCATAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGTCACTCTGGCT
+
(E?@IGGCE?EGICBBEDAGHHCGHEDAA@@DAI@FHIIBIB@FFF@@GEBHG?CCI??AIHH@DIHH@CCCE?GGGIBIHA?BBIE???E@DDDHHEIA
@>chr21:9717746-9717836-0
GAAGGTCCTCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTCTTTGTCACTAGGCAGA
+
HFEHGFFEA@BAHFAHHB???EBACDGFB@IEAEDI@EEBAH@@B@IHACGHF?G??IBH?DIG@B?DEBGCF??HGHD?CEI+G?HF?GF?CHGE?AH5
@>chr21:9717746-9717836-1
GAAGGTCCTCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGACTACAGATACAAGTAAAGAAATCTCAACTCAGAGCAGTCTGTTTGTCACTATGCAGA
+
EI?@GDFE?@?EC@IFABIC?CHIG@IBDBD@CD@B?IDCC?G-GDE?EEIBAFAEC@E@EFCFBBBAD<EEE@FB??GGF@?ED????IAB@BGEGCFE
@>chr21:9717746-9717836-2
GANGGTCCTCAGCNNGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCACAGCTCAGAGCAGTCTGTTTGTCACTATGCAGA
+
AA+FFEBHBEDHA23AAAGGBEHDFCBE?EEEGGIAGIHEHFCEDB?BEFE?E@GFA??AEFECC?6DHIHI?B@@BGECGGFHHI?DBDBAHIG@EFEH
@>chr21:9717746-9717836-3
GAAGGTGCTCTGCATAGTGACAAACAGACTGCTCTGTGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGTCACTCTGGCTGG
+
?GCIAB"FDCF@@?DBCFCABCGE??BGBG@GDC@H$AF@ICFEIBBGEB?FHBHCCH@@E?HEDGDBGEDHAGI@HGHBDCB?E@@?IC?BE?CBFI@<
@>chr21:9717746-9717836-4
GAAGGTCCTCTGCCTAGTGACAAAAAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGTCACTCTGGCTGA
+
EB??EH@EHEGHH@ECH?GI-AIC6H@@EGFFC?@HDGEHAGDHEFADIAD??ACECDGD?FAFGC@@?HGH?DIG@C?GECA@DF@@IDHGHFAADEEC
@>chr21:9717746-9717836-5
GAAGGTCCTCTGCCTAGTGACAAACTGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCANTCTGTCACTCTGGCTGA
+
GGBABIEFIACEEA?CGFF?F?IGH-GH??DEHIGGD@I?G@DGCACDCGHIDH?HCFB@?AECBEDH?GE@DGBGDBEGBA#?EIECBIIIDFAIG@F@
@>chr21:9717746-9717836-0
GCGGCGTACAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTAGGCAGAG
+
F@AEHDCAHCCCGHEBE?DDIDE?@BHFFFBEIBH?HBA?FEDIADBHHHGGCHGHCH@C@H@G-@BHIFDHBAICCAB?FCH@@HAD?DDB?GBGFHBH
@>chr21:9717746-9717836-1
GCGGCGTACAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCCGAGCAATCTGTTTGTCACTATGCAGAG
+
@DDGEGCFHF@EID7?@E?I?AFAFFEFHHGF@@GBGFICCFFEDFI???C?IAH@@H@GA?CGBDDEGBHG,@IH?B$BEDEBCFGAGCBCBAFCEEBB
@>chr21:9717746-9717836-2
GCGGCGTACAGCCAGATTGACAGTGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTATGCAGAG
+
FEG?BCIADEFCDBD@8GD@HID8@DGBGGA?HCFG@FBAAE@@ECHD@AH?BCGCAAADFBFBBDCI@A?EDDBD@FDDEHDHDIAACBHB?GGFCHIB
@>chr21:9717746-9717836-3
GCGTCGTACTGCATAGTGACACACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCNGTCACTCTGGCTGAG
+
IDB!EFGHB@@EAFACEC?BI)AFE@ABC?B?DFDBG?BC?DH@?HDECDC?HBEIEBDAHC?IGDIE@?FIE1ACDB@GEEI@)DHCHHCHEFE?FB?H
@>chr21:9717746-9717836-4
GCGGCGTACTGCCTAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGACACTCTGGCTGAG
+
I?BCHBG@EDFAEHFHG?EIHBAABEDC?BIAEFEHHDDFFCCBIHHCGABDBAFCF?DAABFD@A@IGGEGGIFBGEGI@EA@AE6GCBDA@?IAD?CH
@>chr21:9717746-9717836-5
GCGGCGTACTGCCTAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCTGGTCTCACTCTGTCACTCTGGCTGAG
+
HICH?@GI?G@HII?HE@CGB@FICAHD?B?IDB@EFBEF@D?DAI??HIAHBE?@F?BEHI@HAFCFG?DFG;@IHG@BAC?@@@I?AD@D?BB?A?AA
@>chr21:9717746-9717836-0
TCAGACGGTAATCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTAGGC
+
D??EFGDDDE@DCIAEFAH?@HED@GHHFIF?G@I?IGFAIGG@??@GAHFHGF@BGE@CC?A@F?AFCAIAIBE@E?GDF@@CEC?FCE@DFIHFFFDB
@>chr21:9717746-9717836-1
TCAGACGGTAATCAGCCAGAGTGACAGAGTGAGACCCGGTCNCAGAATACAGATACAAGTAAAGAAATCTCAGCTCAGAGCAGTCTGTTTGTCACTAGGC
+
+GGAAAGB@?CGGBB?HB@C@@HC@EDCD@@HHFGBCBDAB9DCAH?@AFIDHH??@FEIII?A?@@GD@HECGHBFBHHHFFBCAI8?DG@@AIEC@@I
@>chr21:9717746-9717836-2
TCAGACGGTAATCAGCCAGAGTGACAGAGTGAGACCCGGTCTCAGAATACAGAAACAAGTAAAGAAATCTCAGNNCAGAGCAGTCTGTTTGTCACTAGGC
+
AGCCEIDAAHEED@BGHHFBBFBDECB?CECDIIGAFCCGGFIF??DC?DIIC,IDDIFEA?E@FEICF@HDH9/GDEEEECCD@AFB@CG@BEA?E??G
@>chr21:9717746-9717836-3
TCANACGGTAATCTGCCTAGCGACAAACAGACTGCTCTGAGATGAGATCTCTTTACTTGTATCTGTACTCTGAGACCGGGTCTCACTCTGTCACTCTGGC
+
I@I+EGCC??HC@IDBBBEC0BGB?CDHGADEBFCDFHBHF8HA?CEG9@F@DIFD@GHEH??IDDF:IE@B?BGI?I@?CEI@BGEACFBHEAB!BADA
@>chr21:9717746-9717836-4
TCAGACGGTAATCTGCCTAGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCTCACTCTGTCACTCTGGC
+
B?HHFIE@HAEABH@AGIHDE@CIDH???DHIIIAEAFC?F@DF?ABDH@A?GF@DHB?H?DDBD@FBFCHIDEH?GBHBDHG@GF@FGFBBGIFF@FGC
@>chr21:9717746-9717836-5
TCAGACGGTAATCTGCCTTGTGACAAACAGACTGCTCTGAGCTGAGATTTCTTTACTTGTATCTGTATTCTGAGACCGGGTCCCACTCTGTCACGCTGGC
+
HEEHHGBGIBEFDDEAG@-?CC?EGCFHIACADEIFG?FFICGGBC@E??GE9?GGEHADECC??ADGBDDDGDG@DIGFEE,EHCBH?DFCHG5BDDEB
@>chr21:9720705-9720791-0
ACCACTATGTCAGCTGTGACCTTCCAGGCACAAGTGACCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGAT
+
BC@FFG?C?DDB@FGBGDIID?F?FIEFBEIE?GE@@HAEEH@IEAAEIBDF@CEGFIB?A?@IHI?@AG?H@EBBGFBCCIBHC@H@C?EEEEGIDIBE
@>chr21:9720705-9720791-1
ACCACTATGTCAGCTGTGACCTTCCAGGCACAAGTGACCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGAT
+
@AECIC@FE@HAHAIEA@EDBCIEBB@@FICCBE9@F?HF@@IDIACDF@GEICABFECIEIEFFHHHGAGEDCIBAG@FFHHHIADFF@ECGEH?BF@G
@>chr21:9720705-9720791-2
ACCACTATGTCAGCTGTGACCTTCCAGGCACAAGTTACCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGAT
+
BHCB@CCBCHFBCCHH?FBHDC?HIBDGC?FC@C?&?IFA?EEGDICHFCAHIGICF@D@CHGFB@HHCFHICGECFFHGHABDGHICC@D?HIEFAGFH
@>chr21:9720705-9720791-3
ACCACTATGTCTGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGGTCACTTGTGCCTGGAAGGTCACAGCTGAGAT
+
IFHAGH@?@CFABD@F@IFHC@IGHCFDFD@?HEIFGC@HA?@CHFEHD?DCEB@HD@IE?FE@EFCB?BHD?HDHGBECE?GGE@?AGHIA?DHG@BGF
@>chr21:9720705-9720791-4
ACCACTATGTCTGCTCATGATAGCATGCACCTGTACGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGGTAACTTGTGCCTGGAAGGTCACAGCTGAGAT
+
CCFCGGBBAIF?HDDFGEBFBGE@@FI?HDDDFBF*FBEA@HCDEI@BAEEEDGH?DGBICD?FEI?CFF,G@DC?EHFEB?EHDHIADBGDBAG@D@@H
@>chr21:9720705-9720791-5
ACCACTATGNCTGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTTAGCAGGCTGAGGTGAGAGGGTCACTTGTGCCTGGAAGGTTACAGCTGAGAT
+
?IAH?GC?F=CBCFIH?GCH?IEAIDHGI?CEBIB@HIFGDGBHIIEAFHD+E?CA@HFAF?BGIBCCEBBHDEIDEAIICG?I?B+A2B?FIFB?HHA?
@>chr21:9720705-9720791-0
CTCATACCACGCAGCTGTGACCTTCCAGGCACACGTTACCCTCTCACCTCAGCCTCCTAATTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGA
+
?CAAH@D@@@I?DGIBEIG?A@AAFH@AC????=@B-E?AFFGECBDICGG@EAE@ADGG9B?CCG?GHBEABIAHHBA@HAIDIFCDBC?GHDFDHHED
@>chr21:9720705-9720791-1
CTCATACCACGCAGCTGTGACCTTCCAGGCACAAGTGATCCTCTCACCTTAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGA
+
GDBB?CBICHAE@EHHHGHE@A?HF?E@?G??FA@GCC?GD?G@AGGEB6E?B@BGDEH@@HBAH@AD?HCBCAGHICGBFGEG@FEGHBCEGG@EF@BD
@>chr21:9720705-9720791-2
TTCATACCACGCAGCTGTGACCTTCCAGGCACAAGTGATCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGT
+
6G?CDBI?E@A?CII@AADIDHDE@D@GI?BGBFH?GDFEB?FEGEFHCAGD?FI?CFG?D@FAG?H?FF@FBBAICFHIIG@EIGABEG@GEE@GCD?.
@>chr21:9720705-9720791-3
CTCATACCACGCTGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGATCACTTGTGCCTGGAAGGTCACAGCTGAGA
+
C?CBI@?FAGHAHIEFBBAIEHDBIIGEGA@D?HDABECCIF@IDEGFA@ICF@@EDFAD@A?E@D?DICFAI?IEDHHCCEBGC@@B@@DBD@ICGIBD
@>chr21:9720705-9720791-4
CTCATACCACGCTGCTCATNATAGCATGCACCTGTAAGTCCCAGCTACTTAGGCGGCTGAGGTGAGAGGGTCACTTGTGCCTGTAAGGTCACAGCTGAGA
+
HA@B?DHCABHG??DG?GF7EDDFB@GAFHIDDIDHF?EEBAC@DFB@BHCDD,?AFDFAI?IG@CEHFHI@F?DBGGHBDHI*DGCBEGBGEGHGGG?C
@>chr21:9720705-9720791-5
CTCATACCACGCTGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGGTAACTTGTGCCTGGAAGGTCACAGCTGAGA
+
CCEBB@?CCGECGCDBADAEFAD@DIG@B??HIDEHHFBA@@EBG@DA??DEHBGHAB@H@H@?FEGHDGE,DD@F@D@ICGDHHB@AFABACAB?DIII
@>chr21:9720705-9720791-0
CAAGGTCCTCAGCTGTGACCTTCCAGGCACAAGTGATCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTTCAGGTGCATGCTATCATGAGCAGAGATC
+
7DICB?D?GE@II?CAD?@G?CFFAEHGIE@DCBAFE@BG@EICF@FHD?F?BDAHGDB?HBEFD@?BDC@!?IGEHDBDBC@GE??HFAHGADHAAAFF
@>chr21:9720705-9720791-1
GAAGGTCCTCAGCTGTGACCTTCCAGGCACAAGTGATCCTCTCACCTCAGCCTCCTAAGTAGCTGNGACTTACAGGTGCATGCTATCATGAGCAGAGATC
+
F?IE@DFDIDBAGI@DFFFE@?FGCCIGHBHFEBEHEH?A@DDAA?EEGFDIBBG?BEB@II@GE3EFEEIADCF@GIGDGAHG@CFBCH?ADIHFDH?E
@>chr21:9720705-9720791-2
GAAGGTCCTCAGCTGTGACCTTCCAGGCACAAGTGATCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGATC
+
HBFAF@BBHCGFH?BGA?DGH@@FGAIAAICGF@IDIA@DFCE?BHDCEECIB@BEE@BIE@HDG@DE?HBD@DGBI?EGGAGB@FB@B@EFGGIHAF@D
@>chr21:9720705-9720791-3
GAAGGTCCTCTGCTCATGATAGCATGCACCTGTAAGTTCCAGCTACTTAGGAGGCTGAGGTGAGAGGATCACTTGTTCCTGGAAGGTCACAGCTGAGATC
+
E@GGDIGFEE@BACDCFB@CE?IDFF?E@HDEEB?HC/AB?IBIIGAACD@IBEEG@AB?GAIIDFAEHIICAAED9HHICFIBB@EB@F?H@CEI?A@B
@>chr21:9720705-9720791-4
GAAGGTCCTCTGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGATCACTTGTGCCTGGAAGGTCACAGCTGAGATC
+
?BD@HBI@FGE?BBCCB?FIEH?CCBAIED@H?A?@BCC?FG@CGBB@@?ABAB@HAGFDECGHI@GGFHBFGGBEHIADHB?DA?EHC?EADDFHFBC@
@>chr21:9720705-9720791-5
GAAGGTCCTCTGCTCATGATAGCATGCACCTGTAAGTCCCNGCTACTTAGGAGGCTGAGGTGAGAGGATCACTTGTGCCTGGAAGGTCACAGCTGAGATC
+
FIIIDIIIHEIC?B?BF2B?@??FHECBCCHCFA?A@ECA)FA?BBGCBBFEDA@ADHBIB?HEC?BHECDFCEABG??IFIAFIGAGDAI@?HAAC?C@
@>chr21:9720705-9720791-0
GCGGCGTACAGCTGTGACCTTCCAGGCACAAGCGACCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGATCG
+
FHICIEFG@DIBHDFEFBHA?FE@AFHAADBA"BICFIHIDGA?IG?FHCABBIGBHDAIB??B@?DCI@CD?ABCCDEAHEA?@DDHDDDD@E?AEDHI
@>chr21:9720705-9720791-1
GCGGCGTACAGCTGTGACCTTCCAGGCACAAGTGATCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGATCG
+
A@EB??D?B?BIC?AFDCID@E@HDCCIIAECF?GFE?GHB?CE@GCCE@?HEG@GBFC?CC@FHDEHEBHCECBGGFEHE?)?BDHDBEIFIEI?G@?H
@>chr21:9720705-9720791-2
GCGGCGTACAGCTGTGACCTTCCAGGCACAAGTGATCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAGATCG
+
F@CEE.IICACEA@IFBB?AB@A@CF?HHG@C??HGBDFBBHFGIHCHI??II@DH@?@EFCHHF?EBFCCDIAC@FGEBF?GCIG@FHAAC?EDEHDBI
@>chr21:9720705-9720791-3
GCGGCGTACTGCTCATGATAGCAAGCACCTGTAAATCCCAGCTACTTAGGAGGCTGAGGTGAGAGGATCACTTGTGCCTGGAAGGTCACAGCTGAGATCG
+
BC?AFGCCGBGEFIG@EA?AF@F"?EFCFGIICH)GDIAFIAHG?IG??B?BGIC@?HDFIDGEAFDDI@FCFADIIIDE@HB@FAAHH?DH@DBGHEDI
@>chr21:9720705-9720791-4
GCGGCGTACTGCTCNTGATAGCATGCACCTGTAAGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGGTCACTTGTGCCTGGAAGGTCACAGCTGAGATCG
+
?BIA@BBID@CBGD"FFEHAAIDAAF??DEEAIBCCADDB?HA?CFDICB@BGAC@FDDDGFABACIEBDDFEA?BCCAEDEDBDCAAECBDFE@AFDFD
@>chr21:9720705-9720791-5
GCGGCGTACGGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGGTCACTTGTGCCTGGAAGGTCACAGCTGAGATCG
+
GF@???DAF9EI?CGI@@DCDD@@A?HDCIGGDFBCEFH@HGBBDDDFCAF?@F?BHADFEHAE@ABCFGEBDBBAB@HF@AHHHHCHDFGDIE@EBFAH
@>chr21:9720705-9720791-0
TCAGACGGTAATCAGCTGTGACCTTCCAGGCACAAGTGACCCTCTCACCTCAGCCTCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAG
+
@BGBFGB@CFCIGGDC?FIAGAHBECCEIBCFFHFB@ECFB@HHIB@@??A?CC@IEFF?BIBFEDIBI@DE?I?EFHIGF?@FEIGDACC??AFAC?@@
@>chr21:9720705-9720791-1
TCAGACGGTAATTAGCTGTGACCTTCCAGGCACAAGTGATCCTCTGACCTCAGCCTCCTGAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAG
+
BDHA?@EAIAII%AGEEGID?IBG?G?IBBFECDB@EFEDBFHCI&DD?IDGAHDHDHH<F?GBFD@GGAE?IDEA@IECGGEGF@BBBIHHA?G?GEHC
@>chr21:9720705-9720791-2
TCAGACGGTAATCAGCTGTGACCTACCAGGCACAAGTGATCCTCTCACCTCAGCCGCCTAAGTAGCTGGGACTTACAGGTGCATGCTATCATGAGCAGAG
+
CACAAF?DGIBAHACBDFDFBFBE$GGDCG@HIGCGAE?AFEBIFHFEGB?@CCD#HFHF@BE@I@@F?I@@?BBE@D@G?GCDGCCHEHHFGECAACGE
@>chr21:9720705-9720791-3
TCAGACGGTAATCTGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTCAGGAGGCTGAGGTGAGAGGATCACTTGTGCCTGGAAGGTCACAGCTGAG
+
BA@@HAGHH?CD?GEFFECIBBCIACHIHA@CHHD?@ABCDG@HAGAFDA3HABDGDGC?CDHIHFIAHHGFFCDCHC?G@ABED@G?C@?DBICDAGDC
@>chr21:9720705-9720791-4
TCAGACGGTAATCTGCTCATGATAGCATGCACCTGTAAGTCCCAGCTACTTAGGAGGCTGAGGTGAGAGGGTCACTTGTGCCGGGAAGGTCACAGCTGAG
+
?CH@?IBA@HIAFGEDI?DBHF@EFC?DFGEAE@GIB*@CEEE@FIGFICGAIEHHCAGHHFGIEEGA?IH?HFGBFGA@FE.AFADFCBCD@BG?I?DE
@>chr21:9720705-9720791-5
TCAGACGGTAATCTGCTCACGATAGCATGCACCTGTAAGTCACAGCTACTTAGGAGGCTGAGGTGAGAGGGACACTTGTGCCTGGAAGGTCACAGCTGAG
+
@HIHCCE@H@DDH?GBG@H"DH@EACBCFEFBGFCBCCHA@1BC@IDBHIADI@ICFFD?HIC@IDBGGD?$DGA@ABGCAHHGG.??GIDHF@DEEDA@
@>chr21:9720788-9720952-0
ACCACTATGTCAGCTGATTTTTACAGTTTTTGGTAGAAATGGGGTGTTGTCATGTAGCCCAGGTTTGTGTCAACCTCCTGAGCTCAAGTGATCTGCCTGC
+
FDGBIBAFHGBHI?BEGIF?AHE@GACFDEH@EHB?@IC@CC?AAGHADBA?ABBGC?CIFFBI?BAEIHCHI0EF@B?AAGCIHABDFAGD?DA@H?BA
@>chr21:9720788-9720952-1
ACCACTATGTCAGCTGATTTTTACAGTTTTCGGTAGAAATGGGGTGTTGTCATGTAGCCCAGGTTTCTGTCAAACTCCTGAGCTCAAGTGATCTGCCTGC
+
F?HFCHB@BIHEDIDG???EC@H?E,EHH?.ICBHFAFIAHBHBEDCGCADBC@HFBH?A@@@I?G.GIFHE@ID?HIHCAABBH??DAHEFB?EDGFCH
@>chr21:9720788-9720952-2
ACCACTATGTCAGCTGATTTTTACAGTTTTTGGTCGAGATGGGCTGTTGTCATGTAGCCCAGGTTTGTGTCAAACTCCTGAGCTCAGGTGATCTGCCTGC
+
GAIIIADG@IGH@IDAGGAADBAAGADCAD@HGD3IA!BACBC%DE?I?@AC?BHB?C?EBED?BF?@@CBHDDGI@BGHDCADH?4BABCGAEGI@B@I
@>chr21:9720788-9720952-3
ACCACTATGTCTGCTGTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAANCAGGCAGATCACTTG
+
IA?DGE@IAIAIAHI0IB?EH@ID?GAADB@CFIIHDFBBGIC??EEIA?CAG@GDHI@BBGDDIFBBHHBBB?GBEHGEEB?H"CBF@HGDEBDEDHG@
@>chr21:9720788-9720952-4
ACCACTATGTCTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCGCTTCCGGAAGCTGAAGCAGGCAGATCACTTG
+
?FBAAGBI?@FA@F@@@B@@D@D?HFFIHAHEED??FFEAEECI@.DD?IICI?EAHBG?AIH@ECD?4A@ICCEADHHA@?B@FHECDB?ICIFFBEGH
@>chr21:9720788-9720952-5
ACCACTATGTCTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACTTG
+
I?DBCAD@EGFG?E?DED@GCHBCIFFIG@?BIF@3FCDICADADFIH<@GHGGHDICGEGGA@GAEHHHE?BBDCCI@FAA?GDBA@B?BEEDIDF@?D
@>chr21:9720788-9720952-0
CTCATACCACGCAGCTGATTTTTACAGTTTTTGGTAGAAANGGGGTGTTGTCATGTAGCCCAGGTATGTGTCAAACTCCTGAGCTCAAGTGATCTGCCTG
+
G?CBAIIA?BFEIA?BADCGHA?AGIFFD?BHFCGFAHBE6IGCEBBBG?BCGBDBCGA?DEH@IFGE@AF?GABFC@BCI/DIIHIBE?GI@G@BDC?F
@>chr21:9720788-9720952-1
CTCATACCACGGAGCTGATTTTTACAGTTTTTGGTAGAAGTGGGGTGTTGTCATGTAGCCCACGTATNTGTCAAACTCCTGAGCTCAAGTGATCTGCATG
+
@?FEHHDCEDB4BFDHAHFI@AG@@D@HHGEH@IHHGFD3@@GF?@DEADAIAIDE?IB@@I>H@FH&C@?E?HG@CBIEH?HGGAIGHD?IG@GII%DG
@>chr21:9720788-9720952-2
CTCATACCACGAAGCTGATTGTTACAGTTCTTGGTAGAAATGGGGTGTTGTCATGTAGCCCAGGTATGTGTCAGACTCCTGAGCTCAAGTGATCTACCTG
+
@CGBF??ACHB4AIEEIBBC"ECE?DHDC/BECIEI?DHCEAHD<HGFEFEDDGAD?BIEFGGIFE@EDEEBC'EABBCE@ICAHDHGACHCACI.IC?H
@>chr21:9720788-9720952-3
CNCATACCACGCTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGNAGATCACTT
+
C7?FDBAEIGG?EHDGCICHBII?@B@BBECHAIECGC@FAHEAAEAAECFBHDG@BBICGHHHHD@HCD??ADHCFFH@AFGBFAF?BA/EC?C?EF??
@>chr21:9720788-9720952-4
CTCATACCACGGCGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACTT
+
@FAG@?GGD??<(E?E?CEDCGAAFB@BFHAGHGD@HIABHE'F@GECDHF?C@BGHFGA??EFCFAAHEF?F?CBEAGE?ICAF?FH?FGFAIEEHECF
@>chr21:9720788-9720952-5
CTCATACCTCGCTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACTT
+
HDHAHIHD5@HAE@ICEF=E@?BDEGG@E?AA@GG??ACHCBG@F@ABDB?EDAH?G@D???E@?FBF??IDD@BADCBEHEGD@HAEHFI?DAFEHFCB
@>chr21:9720788-9720952-0
GAAGGTCNTCAGCTGATTTTTACAGTTTTTGGTAGAACTGGGGGGTTGTCATGTAGCCCAGGTATGTGTCAAACTCCTGAGCTCAAGCGATCTGCCTGTT
+
AIIAFFG*GHCFD@D?DHDHIIECADA?D?ABIHI?E)??ADH-DDIFGGCHH?@CD?DEIFD@FCFHCBHAG?DB?CHGFCHAC?I5GAAIE@FA@G=F
@>chr21:9720788-9720952-1
GAAGGTCCTCAGCTGATTCTTACAGTTTTTGTTAGAAATGGGGTGTTGTCATGTAGCCCAGGTTTGTGTCAAACTCCTGAGCTCAAGTGATCTGCCTGCT
+
FAAI@C@DF@?CHFEEAA'ICIFD@?DBE0I4HD@FCD@D'EBEHCGHAAGH?AD@AHEAA?EG@?IGAGFCFCIHICI?FDEBFF?IIBFG@C@HEFAB
@>chr21:9720788-9720952-2
GAAGGTCCTCAGCTGATTNTTACAGTTCTTGGTAGCAATGGGGTGTTGTCATGTAGCCCAGGTTTGTGTCAAACTCCTGAGATCAAGTGATCTGCCTGCT
+
CCC?IBGHB?AABHG?DD&CH@ADFCI9AFAH?C?#DEDEDE@@FEIHCECDGDBDGIC??GD@B?HFBCEEBG?@B@IDC+IHCFIHB@GDI???E:AA
@>chr21:9720788-9720952-3
GAAGGTCCTCTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACTTGA
+
HHDBFDBEBBEACB@I?GAFDFGIGCBHBIDHEBICEDEE?EDEAHEDGECDCFAH@@IEFEEFGAD@EDIABFBHEGEEF@CAHIA?CB@CAG?CGHCI
@>chr21:9720788-9720952-4
GAAGCTCCTCTGCTTTCCAACGTGGTTACACCAGTGGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAAGCAGATCACTTGA
+
BB@@<@FCDFA?CACEEDAD<I?CFGDE@AD@IIB1B?IDEAHCAEDDCGBIDBAHDA@@BFGH@BF?FF@DCGDHCGBG@G@FBH1@AAIEC?C@CFBG
@>chr21:9720788-9720952-5
GATGGTCCTCTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTACCGGAAGCTGAAGCAGGCAGATCACTTGA
+
ED!GDDH@CD?FDDIA@GGD?E@:IFH@DFAHHADGFCEIBBFBHHA@CG??IIBAGA?BADC@G@DBAD6BBAGAG@IHCAH@FDFDF@ECG@BIGCAA
@>chr21:9720788-9720952-0
GCGGCGTACAGCTGATTTTTACAGTTTTTGGTAGAAATGGGGTGTTGTCATGTAGCCCAGGTATGTGTCAATCTCCTGAGCTCAAGTGATCTGCCTGCTT
+
BIACEFHHGEDCFCFBGCCAEBIF?BA#A@@@DIEAID@HG?HDE?GGBIGGDDB?EGAFE@FE@HCHHH@,EE@FBGAH@AFICAADGAGFAG@H?DBF
@>chr21:9720788-9720952-1
GCGGCGTACAGCTGATTTTTACAGTTTTTGGTAGAAATGGGGTGTTGTCATGTAGCCCAGGTATGTGTCAAACGCCTGAGCTCAAGTGATCTGCCTGCTT
+
BBDCIACEBIIF?IE@DD?HF?GGC?A?@BI?AA?AE?FH/FC@G?DGDFB?DCA@@E?AB@?FBAGGHADHB>FHBCGI@CDCG?AAGHDBA@GBACIE
@>chr21:9720788-9720952-2
GCGGCGTACAGCTGATTTTGACAGTTTTTGGTAGAAATGGGGGGTTGTCATGTAGCCCAGGTATGTGTCAAAATCCTGAGCTCAAGTGATCTGCCTGCTT
+
D?DADF@DAABAG@FGF?@7F@HI@BFCACC@DCGDG?DG@E5DIACGCEGFFBHHG@HHGBCD?GCBBDDH$FEDD??BI@BGHF?GEDA@AHACAFBH
@>chr21:9720788-9720952-3
GCGGCGTACTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACTTGAG
+
CC*GECFIDG@FGFHIBFAGB?FDEA?@A@ACGII?G@ICAID@GGIAH@CDFFDC?BE?GDCDADD@?I@HBAECCG@FHBHII.H?ABA?A?@FCAA@
@>chr21:9720788-9720952-4
GCNGCGTACTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACTTGAG
+
BE*GFEFF?AIAHE?BIDAHCDCEFGID$GBBDADFA?F@EAB@AB@HFEEAGECBFBEB?F?FEEEFCGBCHG@GCDGAA@@I?CADEEFE@BEFGIDG
@>chr21:9720788-9720952-5
GCGGCGTACTGCATTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACTTGAG
+
@II?HI?AGFDH(A@HEE?BDHG@?GGG?EEBH@?IBI??CBGF?C@@HD@?IAG@?@?@FDHIBAA?HDCGHBB?EDEGHC@CHECAAE?DHAFIGBBD
@>chr21:9720788-9720952-0
TCAGACGGTAATCAGTTGATTTTTACAGTTTTTGGTAGAAATGGGGTGTTGTCATGTAGCCCAGGTTTGTGTCAAACTCCTGAGCTCAAGTGATCTGCCT
+
DCFDDBEAA?BCDG@)HE?DDG@DDECICIAA@F?C@@H?IDHFCDD?D@?AFICABABEHIAD@CI@@DFDHEI?EBEEAIGIEDGAHIGFH@IEDAEI
@>chr21:9720788-9720952-1
TCAGACGGTAATCAGCTGATTTTTACAGTTTTTGGTAGAAATNGGGTGTTGTCATGTAGCCCAGGTTTGTGTCAAACTCCTTAGCTCAAGTGATCTGCCT
+
ADCB@@GBI?F@FGBFBEIBFIEFIBFC?EAG?@C@GBIA)E!@CHHEIHAHDAIHABIBD@?AFEIIIFBFAAACEHHE?,AB?EBFIBHF/BDHDHFC
@>chr21:9720788-9720952-2
TCAGACGGTAATCAGCTGATTTTTACAGTCTTTGGTAGAAATGGGGTGTTGTCATGTAGCCCAGGTTTGTGTCAAACTCCTGAGCTCAAGTGATCTGCCT
+
BA@@ECEH?DD@IABDFHEAAIEDC@IHD*EAG@G@EHAE?A??HIFBECDCCG@GGFBB?GCFEIEIGHCFDDCFAHCIDCC@@?HHH?BIC@CCGF?A
@>chr21:9720788-9720952-3
TCAGACTGTAATCTNCTTTCCAAAGTGGTTAGACCAGTCGGGCATGGTGGCACACACCTGTAATCTCAGCACTTCCGGAAGATGAANCAGGCAGATCACT
+
AGD?BI3HDCHFB?,?DBIH@IDG@DDAHCD9@GBF@HG?EBD@BA?EGB@BHC@GHE@CHEDGEG?FGBGCC@B?A?EF@0HHEE8GBHGEF@FEAG?B
@>chr21:9720788-9720952-4
TCAGACGGTAATCTGCTTTCCAAAGTGGTTACACCAGTCGGGCATGGTGGCACACACCTGTAAGCTCAGCACTTCCGGAAGCTGAAGCAGGCAAATCACT
+
EGGAEHECBHHCG@E?GHEFCBCGDG@EFA@H@AE?AIABCBC@FI@B@@@@HBB?FCCI@BE+DA?AB@AAIGD?B?FFBEAFBFCFC@EG@,B?FCE?
@>chr21:9720788-9720952-5
TCAGACGGTAATCTGCTTTCCAAAGTNGTTACACCAGTCGGGCATGGTTGCACACACCNGTAATCTCAGCACTTCCGGAAGCTGAAGCAGGCAGATCACT
+
CA@GICIIIBGCEHH>IEADB?GH@@=GCCAHGFFCCHFHGCCG?AGB>AIGDIHGG?#HIECC@ADEHGEABIFAHFGE?ECABG?FCFHAFHG?H@EI
@>chr21:9727665-9727729-0
ACCACTATGTCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
G@BFAICEAIDCIGD@IFC@H@@IFIBBAGBGIDBIACA@DCA@CDGHE@I@HEA@IEHCDABEG?IB@F@GFBBAAH?CH?ADF?FFCBG@GHHEABHH
@>chr21:9727665-9727729-1
ACCACTATGTCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCNATGGTGTATGTACGCTGAGGTCGGAAGAGCGAAAAAAAAAAAA
+
BHDF?GHDFIEGGDG?ACBAHAFG@CFDDIAHBICAB?FFAHHHGHHHDGIIGCGB=BABA@A@F@ICDIFDCDHH/D@DAC@@AAHHBBA@HA?FA?A?
@>chr21:9727665-9727729-2
ACCACTATGTCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATGGGAAGAGCGAAAAAAAAAAAA
+
FIAFFDDCCBCEEFG?FFGDIGG?HIAF?GGIDI@FD@AH?EE@AHBAG??FBBGC@GHGB?DCC?FEEA@I@EE?E?;IEGDID@HFFI?GAEIE@@HH
@>chr21:9727665-9727729-3
ACCACTATGTCAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
BEIE@C?BGAEACICCIHE@IGECEFGH@IAA??BEDEHFBBDCDDIGAHI?C?I@HFBDEDEEEAAAGICEG?CEFIHFBHH*AFIHHHHC??@?B?GE
@>chr21:9727665-9727729-4
ACCACTATGTCAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
?H@@IEIA??CBDC@?BBEHH@ICH?F@?CC?EDFC?E?GFFAE?AABGBAEBH@FGAAFCGFEEAF@B@HF@@AI@DEIBADA?HDDBAEEGFBCA??H
@>chr21:9727665-9727729-5
ACCACTATGTCAGCGTTCAAACACCATGGAATACTACACACCTATAAAATAGGATTAAATAATGTCTTTTGCAGACATCGGAAGAGCGAAAAAAAAAAAA
+
F?AI?GDGBGG??E?G7EB>D@AAIG?H@CAGHABFBIDCGB@@BI?EEGEAIHD/AGHIAG@@DAAADDDG?CH!@@AHHADGBDCCDDBFAFBHIFDH
@>chr21:9727665-9727729-0
CTCATACCACGCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
EEI?@@IGIDHF?CAC?@EDFF?EH@DICEH?IFBICEDBGGIFFGG??@HFAH@A@B?I@FCBAGA@HD?GEI??HFCAE@DH?GFB?HBBIG??DBDA
@>chr21:9727665-9727729-1
CTCATACCACGCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
@IFBB@DACGFII?ADAFDF@D?GA@BCHIEDIEDBECHFEAFGHD?FHBFACI@ACFB@?GHGAGAGD?@HICADECEEFIE@AFAEABDCH?E@FCD@
@>chr21:9727665-9727729-2
CGCATACCACGCTGCAAAAGACATTATTTCATCCTATTTTATAGCTGTGTAGTATTTCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
G$@E?CAAF?BH?IGFH@@BF?DD?A?CBCCHDAHAFBCF@FCI),EIDAFAEFBB0HAIHACAGG?@ADEAHFII?GAEECGIG@@D?FF@DBAIGC@D
@>chr21:9727665-9727729-3
CTCATACCACGCAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAGTAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
B??FICG@@IFF@CIDCBF?A?GFBH@CABFCE@DC?HAA@CDABCE?BF?IA?I?GCC(CIGADE?EAFDBEGFIC@GIFBICGGIGH?F@IBGIA?@I
@>chr21:9727665-9727729-4
CTCATACCACGCAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
?CFDBI?B@AE*GDGHAAI@CB@IGIAHCADAGHIHBEFHIBAAEBFEGECIHDD?DI@GAFEBCHIDDHIE@?AI@FFH@BEAAC?EDCCF?I?IFHG@
@>chr21:9727665-9727729-5
CTCATACCACGCAGCGTACATACACCATGGAATACTACACACCTATAATATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
DDG@@GH?D?@@FFF@CHEFIBDBDIHHF@FGAEHHHCF@FF@ICCBD7CFG?D@HFID@FB?EAB@ADGFA?EDHHHCBGB?FCHD?IECI@F?D@DDB
@>chr21:9727665-9727729-0
GAAGGTCCTCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGNGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
BEHHBCEFA?CDCHFB?GFBGFGCGBFBF@E@I@AHCBBCE@HCI.AGHE?@GCHHHCBHD?EC?@IIBCICE?AFCECAGAD@DHIGDIFECCEGIFBE
@>chr21:9727665-9727729-1
GAAGGTCCTCTGCAAACCACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAACAAAAAAAAA
+
?B?IBFAAFF@BE?BG/<@CADIHHCC?FGIDAAIBAI?IIC@FFDHDHDF@FEFCFG?@AE?E@IHAA?BCC@A?CCC@?GCA/BGE@H)DC?@GADAA
@>chr21:9727665-9727729-2
GAAGGTCCTCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAACAAAAAAAAA
+
??F@GCBEHICB@BA?ABHCBAHEEC@EAAFD?IAB@BGAHGIHFDIBAGBBI@??GGBAHAEEHBFGBB?GHDHGFHEF?CCAAHEHGA5CCH@E@IFA
@>chr21:9727665-9727729-3
GAAGGTCCTCAGCGTNCATACACCATGGAATACTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
EDCICEFFHAIHBE?7DAIIHBBC?HA@CE?BCIHIHDEDGAHHDCFGICAGAFBCEFEEE@I?AB?AFEIHCB?FCH?IHIAIFBF?DBFI@ABDEBCC
@>chr21:9727665-9727729-4
GAAGGTCCTCAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAATATTGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
EDC@ICHCCGIEADHFGBFHH?F?CICB?FEEC@DC?CDE?GHGHIDA@GIB@?E@B@I?-@GFCG@HG@@EECI@H?FD@@FFH@CE?FHHFG@BCGC@
@>chr21:9727665-9727729-5
GAAGGTCGTCAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAANAAAAA
+
@@FE?EC$IBECEFB@AAGEICH@@C@C?DHF??EHI@@AA@GEEFFADGDCFEHFF?FIIIIBEAHHD?A?DGFBCBF?DCABABAGH?I@C@8@CABE
@>chr21:9727665-9727729-0
GCGGCGTACTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGTTCGGAAGAGCGAAAAAAAAAAAAAA
+
CCDCGEAGFICHADBCADAAGFFGBHGCCBI?IECH?IFBIAIEDDD@BEIHBFCFEI?BCDAC?GHEIBB@ID&AECBHE@?EFEIEFDHCABHAEECI
@>chr21:9727665-9727729-1
GCGGCGTACTGCAAAAGACANTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGNATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
?GB@EEAGC?H@DFHGFCGA6?IBEBFEFDEAGE@BA@GEDIIEDGI@AFHBA??BBHHDB>I?CAI@GEDB?IBE@FI@EHHCHDEGDDH?CF?A@?AG
@>chr21:9727665-9727729-2
GCGGCGTACTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAATAAAAAA
+
C@ABH??BEAAGG@HGGGBAC@IIGECAAH?E?IIF?AIEFEDEFA@GAEEEC@IIHE?I?CHBCGGG@HGIFGC?@B?DBC??@GAHGHHHG&FBFBCG
@>chr21:9727665-9727729-3
GCGGCGTACAGCGTACATACACCATGGAATNCTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
FII?DDBBEAIAIFIAHG??AB@IFFH@H?4F@A?B@F??BGAC@GCFGFHIA@BFC??IEDGIBFHGIAC@CIDIGBFHHBFFABBE)@@IICBHC@GF
@>chr21:9727665-9727729-4
GCGGCGTACAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGNTGAAATAATGTCTTTTGCAGAGATCNGAAGAGCGAAAAAAAAAAAAAA
+
EGC?F?HEHAHEEFAIAGCAF@GFGDFEA?GDGCA?IICAGDAIEFE?CEA)F@DICCD@?EGIHGIDBIE@F?BEC'BBFEACHFDAFGBDAFFE,GAE
@>chr21:9727665-9727729-5
GCGGCGTACAGCGTACATACACCATGGATTACTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
DC@CI@?ECCHAAEEFHHBIAH?FFDEE#EA@@DE@BAE?E?@FGH@BG?E?E@@FDEGII?IHDBGGF@FEIB@D@?C?GCF?HGD@EHFHC@CGFDG@
@>chr21:9727665-9727729-0
TCAGACGGTAATCTGCAAAAGACATTATTTCATCCTATTTTGTAGGTGTGTAGTATTCCAAGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
CB?G?DFEF@@AFHGIIEHI?BHF?DABGEH@AEIGIHAFE1D@IGDEEBADF@CBHIFB=H@?AGEFADIDHDGHD@FDH@CFBFGDGC@GCBFD@EAE
@>chr21:9727665-9727729-1
TCAGACGGTAATNTGCAAAAGACATGATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
CFA?@DFAGA@I9CD@@HBDGEGB@.@HE?AI?DHCH?DH@HF?EIB@ADAABEIEHE@DIHG?CBBH@&IBDECI@I?CCBECFGI?IGBF?@@CCIDB
@>chr21:9727665-9727729-2
TCAGACGGTAATCTGCAAAAGACATTATTTCATCCTATTTTATAGGTGTGTAGTATTCCATGGTGTATGTACGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
IGGEHAHDEAI?AG??GBAABEHHEDCHEFI@?GF@DFEB?FFB@EGEBHD@IHIBAIGAF?BB@?C?CBHGHFEGCAAIFBDABBAADGFF@DGDDBFI
@>chr21:9727665-9727729-3
TCAGACGGTAATNAGCGTACATACACCATGGAATACTACACACCTATAGAATCGGATGAAATAATGTCATTTGCAGAGATCGGAAGAGCGATAAAAAAAA
+
B?EB?F@GGIG@:HDFC@CCID@HBIBE@CDIIDC@DCHD?G@CI@BE>@CI;G@CDBGBEDGIHA?F"F?H@?IAI@@DE@HAEDFI@CA%BFIDG?DB
@>chr21:9727665-9727729-4
TCAGACGGTAATCAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAATAATTTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
D?ED@?BD@IDHDDDF?GAE?HFAEAGIABBFCIEEGGCEBC@IBBDBAI??BC@GCCB@EIDBI3C@HFA?@A??CEAG?@B?C?DFCGCHGBACB@AG
@>chr21:9727665-9727729-5
TCAGACGGTAATAAGCGTACATACACCATGGAATACTACACACCTATAAAATAGGATGAAATAATGTCTTTTGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
?DGHE?BBHFG?$F@GH@IFEBECGEDAIGBHHA@BIDB@GFD?BHGHIAAFB?@?EH@?B@D?@BF@IGHFEAIBDBFFEDC@HDABDB??HHC@EB@E
@>chr21:9741160-9741246-0
ACCACTATGTCAGCCAAATCAAATGGTCCTTTAGTTCACAGTTGAGAATTTGAAATTGGAAGGGAATTAACATATGTAAGGATGATGTATTTGCTGAGAT
+
A?DFHFHFA@HFE@CIIHDI@@IFGD@@FC?GA>???B?E@IC?AHBAFCDHFCBGDGFBGCD)FGBG@DHAFEGCB?BDIHA?IH>I?GICDE??E?CD
@>chr21:9741160-9741246-1
ACCACTATGTCAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGTGAT
+
H@IB@BFFABBBD?GB?HAEECBBFAIBHCBAGFAAD@CHI?HEFA?FEGFE?DFF?HHBBEC?E?DDC?@EAI@E@AA?HHGGACAB?@D?BCAG8DAE
@>chr21:9741160-9741246-2
ACCACTATGTCAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTTATTAACATATGTAAGGATGATGTATTTGCTGAGAT
+
CIGI??EDE@F?HH@B?HCIGAIFBDGIFHACCEHD@HBCCAED@CD@@@H@G@DBCDB@DDA@<HDIFC@CCIGFHH?HHHIGCDGGAH?HGCAFDI?A
@>chr21:9741160-9741246-3
ACCACTATGTCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTTATTTGGCTGAGAT
+
GGCI?ACGEGHECFE@IID@GCA?E?I@AICDCEIBDIGACAIH@FC?CEHF?C??AHG@EDB@HDIHAIDCHFIID?IB?HHGHHGIIGGDIICACEBF
@>chr21:9741160-9741246-4
ACCACTATATCAGCAAATACATCATCCTTTCATATGTTAATTACCTTCCAANTTCAAATTCTCAACTGTGAAATAAAGGACCATTTGATTTGGCTGAGAT
+
@GEACAFA&FCEFHE@EFCHIHFDG?CHF:DHCGFFACCICGGIG@BICAC!DDBI?DHHIHH?ACA@E?@DCABEH@A?DB@FHEGBG?F@AIGADB@F
@>chr21:9741160-9741246-5
ACCACTATGTCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAAATCTCAACTGTGAAATAAAGGACCATTTGATTTGGCTGAGAT
+
EHAGEIFB@?@?AE@?BAHDEGIBHBF?ECH@F@@C?IF?HEDADIGCGEGD?D?@ED$DC@?CEEHHFHGDF@AIEE?I@CF?I@A@FIHA@GGDBBH?
@>chr21:9741160-9741246-0
CTCATACCACGCAGCCAAATCAAATGGTCCTTTATTTCACAGTTGGGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTNCTGAGA
+
CI?EB??GE?IBGIDBGFAGFCHH??AF?DEFI?IBF?DBG?DDI2GC??DE?AFAGFAID@BEFD?CDCF@F?I@@H?CIIAHG?@FGFIEH<F?FFG?
@>chr21:9741160-9741246-1
CTCATACCACGCAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGAGGATGTATTTGCTGAGA
+
IBFICIF@FIGH@E@FHEHDHFHFI?DFIGGAC??0BHDFIAFAFDFDCIH?CDCGBDFFCH?@FI?I@HAECICCHDI?@@?,GBDAG?EEHBCGHB??
@>chr21:9741160-9741246-2
CTCATACCACGCAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAGA
+
EIHBIA@??BFDFAGFGBE@DB@?EDCBIIDB@CHCHD@DEHICE@A@@EHH@HHBAAD@G?AEIIB?@IIEAHEHE?@CCA@GH?HD@??FCGAFH@CI
@>chr21:9741160-9741246-3
CTCATACCACGCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCNACTGTGAAATAAAGGACCATTTTATTTGGCTGAGA
+
CCGIGEFHHAA?@FI@GEEBHH?BHI@DIACIHEHGDDIFFBEBBAB?AAHCFBBFIG@CF??G*DF?FA@?C?@ABCIBCEF'FACAHA?D@EBDFBHC
@>chr21:9741160-9741246-4
CTCATACCACGCAGCAAATACATCATCCTTACATATGTTAGTTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTGATTTGGCTGAGA
+
BEGIFHICHFFIEBB?FHD?@A@GEGH@HDF@ABFDFBHE+DE@AE?DB@AGFGHEHAAG?HEGFIIA@I?B?CAGGEE?EDGICFAIIHBHHHCIHADF
@>chr21:9741160-9741246-5
CTCATACCACGCAGCAAATACATCATCCTTACATATGTTAATTACTTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTGATTTGGCTGAGA
+
ABGAFG@EBAA?DFIF@AIDH?DHA?CBCAHGBI?ICD?IACFHH$0HBF@GFFF@BDEI@EIEIEEGAE)GBBBCH?EBHAE?E@?ECDC@B?GI?BHI
@>chr21:9741160-9741246-0
GAAGGTCCTCAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAGATA
+
EDGIIFFBACCIHCB@DBAFHGFHBE@?F@FA@HDBFHAAGD?GEAAC@EBDH?@CECEDFGIH?@CI?FGBGD?HBEDECD@BEIA?AD?@@GHFDII)
@>chr21:9741160-9741246-1
GAAGGTCCTCAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAGATC
+
B@?@HBBDGADCC?E?E?CBDCBEC@AGGFA@CBHG@IFH@ACEDHIBFHGAHDD?@DACAEFBH?CG@AA?I??HDHDHCE?I?DEAHAFGBHEEHDFA
@>chr21:9741160-9741246-2
GAAGGTCCTCAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGGTGAGATA
+
@CCBGIFI?BDIIBIHBCD@BHF@@HHBIIFEHDGAEBCA@@CBFFAA@EBAHAED@HCHEEAEII?FFGC@CFIHGFAC@DAFDI@AH@?F*AAEBAC0
@>chr21:9741160-9741246-3
GAAGGTCCTCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTNCAAATTCTCAACTGTGAAATAAAGGACCATTTTATTTGGCTGAGATC
+
F??ACE?C?C@HFIG?IHBBC?GCB?EEDEGI@IA@EF??EFAAAHIHABCD&@GEH@BGG?EIBEFD?FG??GIHHIEI?FBC@FAIBFCGGIFIGDI@
@>chr21:9741160-9741246-4
GAAGGTCCTCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTNTGAAATAAAGGACCANTTTATTTGGCTGAGATC
+
FFEECHAD@CIIHG?CBHHDAFB?ECABG?AHDAFIFHHGDAHHCGFE??@HFC?HCAF?CAFHGA<DHBADEDE@HAB?FE%GG?@HAHEA?@FAFCHE
@>chr21:9741160-9741246-5
GAAGGTCCTCAGCAAGTACATCAGCCTTCCATATGTAAATTACATTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTTATTTGGCTGAGATC
+
?CDF@F?FGGADBGB0BEH?G@?*DCB?>?BEI@@G!@GFFBE.EHAHGAB?CDD?HEDIIGBFDBDHHIAIGHEE@EGGCHD@DH?ECA?GGDADCD@E
@>chr21:9741160-9741246-0
GCGGCGTACAGCCTAATAAAATGGTCCTTTANTTCACAGTTGAGAATTTGAAATTGGAAGGTNNTTAACATATGTGAGGATGCTGTATTTGCTGAGATCG
+
F@AICAIA?GIFE/HHABI?AA?HGDB@?CH.IAA@?BBACIC@CACCGGBEDBG@A?FHG5:"?IIA?GA@BCH<@IFEDD=BIDEF@EDAHFBIGC?C
@>chr21:9741160-9741246-1
GCGGCGTACAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAGATCG
+
CIEIDICFGCDD@IAFIEAE?FAD@EFDIC6FF??B3A?HCDCIBH?H?D?IIG@BBIAAF@IIBDDGFIF@@?@A@C??AEF;D@A?EAGEHC@AGHAG
@>chr21:9741160-9741246-2
GCGGCGTACAGCCAAATAAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTNTTTGCTGAGATCG
+
DI@GIB8HIB?DBAIHBC@?AAGGBE@HB?F?F?FCDGB?FHCGGDBABHIDGE@CFA?EHE?@DFG?I@BIDEHHEFACAIBHBF3GDHIEGEDGBEAC
@>chr21:9741160-9741246-3
GCGGCGTACAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTTATTTGGCTGAGATCG
+
CABBIBGEIIEHB@?AEGDE@IDA@CGIHBEDICBIF:A?EACID@GEGE@DDCED?I?F?AF?@GGHB@??ID9HECECGICHDFCA@HFDAEG@IBEH
@>chr21:9741160-9741246-4
GCGGCGTACAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTTATTTGGCTGAGAACG
+
ID?@DDBH@G??HIEI@DEE@@BE?HFGFAHF@@@DCDD@EGAFGEDCACADEEADFGH?B@?BDBACADFI?DHGF&BICFF?HCAG?IDHHFGCD;D?
@>chr21:9741160-9741246-5
GCGGCGTACAGCAAATACATCATCCTTGCATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTTATTTGGCTGAGATCG
+
FG?EDE?AGIIF?FCBFAHB?BA?GC?7C?ED?C@DBH@BGGAD@BA@IGF?@F?FHG@ADDFEEAFFGIH@IHDEH??A@@CCBICEDG@HHBDGGCFB
@>chr21:9741160-9741246-0
TCAGACGGTAATCAGCCAAATCAAATGGTCCTTTATTTCACAGTTGAGAATTTAAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAG
+
ECHBBFCCBA?F@EH?CC?IHHDHH?FAC@A@BCFI?I-HC?DC@@GE?@@?D*DGIAA?DFACED@IIFEFGBHHCDHGABD@CG?HIIBHCICEAAFC
@>chr21:9741160-9741246-1
TCAGACGGTAATCAGCCAAATCAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAGTTAACATATGTAAGGATGATGTATTTGCTGAG
+
GGAB@AD?A?F@IDAA?E@DD??GB?FIAC?@FHB?@B?AGC?@E@GEE?HEADICADID@?@IGGF&G?CFCIBAAIFB?HC?EBABFD?EGHGGDBGH
@>chr21:9741160-9741246-2
TCAGACGGTAATCAGCCAAATCAAATGGTCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGTTGAG
+
GGHAHBGBIH@FECEI@DHHB?ADGCA?GDIBCAIBIHEBFDE@?F?EFD@@IB?EAEE?D@CHEEGDAIGEEGDAHAGH@?EG?ADG@IFBCAE=IADI
@>chr21:9741160-9741246-3
TCAGACGGTAATCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCATTTGATTTGGCTGAG
+
?AAECCBFGI?:E?FHIF@FC?HDEGGI@AHEEE@C???@D@@?HFEGCBHFGD@DF?@ADFCEEABEAFHECBEDCAFGIB@EGHEGC?EBIIHGHBEC
@>chr21:9741160-9741246-4
TCAGACGGTAATCAGCAAATACATCATCCTTACATATGTTNTTTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGACCAGTTGATTTGGCTGAG
+
I@CIH?BHIGBHFAF?!ECAH@HG@IFEGDC@FBIFH@GF=1IFECAAIBAAF??HA@AIHGGCDBDBDGHD@ECEHF?H?CDIA=GIICGEI?HBEC@H
@>chr21:9741160-9741246-5
TCAGACGGTAATCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATGAAGGGCCATTTGATTTGGCTGAG
+
EHF?GIE@EFBFDCADBGIBDBHGI@EBE?A@GGCBE@IGBIB@D@FAHI@CDECCCICDCDHGEGACAEG??EEE9CAI?;GC?HHEGF?E@EABF@CD
@>chr21:9741868-9741937-0
ACCACTATGTCTGCTAACCCTAGCCTACCACTAAATCTTATGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTCAGCTGAGATCGGAAGAGCGAAAAAAA
+
BAEII?H?G?I@I@A?DI,HDGGFE!HFCCGD?IEAFIFC+B@EGBAABCAGHIF@GACAAIFBGFAF?FADA-BEAAEGIGEFDAHHBCF@HIC@HDHA
@>chr21:9741868-9741937-1
ACCACTATGTCTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAAA
+
D?A??D?FHDF?CFBF@?FHIAGIDDHB?GF?ICGIEDHHIAD?DBCCBEBDAIH@IFDC@@FB@BBEEBE?BBEDH?HIAIADHFAB@CCE@E?AGAFD
@>chr21:9741868-9741937-2
ACCACTATGTCTGCTAACGCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAAA
+
IID?8?CEHD?BBDE?HB*HICDCBBGG@?DIBDEGEIHGCBGED?GGCHCGGHAGGHCD@I?CCHA@HAE?I@DIHBEFFCGAH@?IFFHECDHFCIH@
@>chr21:9741868-9741937-3
ACCACTATGTCAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCNCACCTTAAGATTTAGTGGTTGGCTAGAGTTCGCAGAGATCGGAAGAGCGAAAAAAA
+
EAAC?EFCEB@GFCIB@FDHGH@CIDFIAFDBDA;EAIABEDA'BDAG?C@AFHCE@EDDDDI?IFDFDFIIGD+BECCI@BBIFIHDC?DE@IHA@F?I
@>chr21:9741868-9741937-4
ACCACTATGTCAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTTAGCAGAGATCGGAAGAGCGAAAAAAA
+
ABGBHFGGHBFACIDBCBGDEEDHFH?IGFBB?GIFBFI?CB@@DBA@DHDAFFHH?DFEA@IC@D@BH?A?EAEIDEC@@FFDEAF?GGB?FH@CE@FE
@>chr21:9741868-9741937-5
ACCACTATGTCAGCTTAGCACCCAGCCAAAGCCTGTATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTTAGCAGAGATCGGAAGAGCGCANAAAA
+
F@AIGGHFDIA@AGIF@HEHDHIICG@EHA?IHD?8H@IG@HCGCI2?CCBDDBBIC?FA?HD?B@CCIIA@EBEHCBIGBA@E@CHIIHIHC,A$IHA@
@>chr21:9741868-9741937-0
CTCATACCACGCTGCTCACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAA
+
?AAHF?AIHHACGDIGCGDHEFA?@DHFDCF@BBEBCGG@FD??CID@FHBBFBFA?FEIBBCCDC@I?H?@E?I?GC@AGEBDGDHF@EGA@IIHH?@C
@>chr21:9741868-9741937-1
CTCATACCACGCTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAANCTGAGATCAGAAGAGCGAAAAAA
+
BE@ABBADFIFBBIGCHFEIH(EDHCECAF@GHDFEB@FFB@DIC?IF?BAEGAAHGIHADAFBHFGFFDIBBG?F7FDGCDHG?+IBCF?F?DDEFFEE
@>chr21:9741868-9741937-2
CTCATACCACGCTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGATAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAA
+
EFB@DBBA?HECG@AAIGA?FEIIID@FEBGBHEGF?GEE(CF@CFDF@;D?FHDE?CGDE@HAFEC@IBAEEIBCBI@CHHAEIH@EIAD@?A@FBEE?
@>chr21:9741868-9741937-3
CTCATACCACGCAGCTTAGCAGCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTTAGCAGAGATCGGAAGAGCGAAAAAA
+
C?D@H??IG@GFEB?CIFI?@-BD?GCFBBBHEDBFEAAFGGEBDG?FIFCDBCHID?CDDFHIIG?A?IDEGEGIIECEEFBIEGEBA@?EFHFD@?AE
@>chr21:9741868-9741937-4
CTCATACCACGCAGNTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTGAGCAGAGATCGGAAGAGCGAAAAAA
+
I)@HCE@EHGDBCE5?GIFBBCACDCAF??@FAG?@CBDGCG?CABDHACAFCCIF@DGGCGEIBBC?AEBEDICGHG@IHHEAECBAGHCAHDI?AID@
@>chr21:9741868-9741937-5
CTCATACCACGCAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTGAGCAGAGATCGGAAGAGCGAAAAAA
+
@ICAHB?AHG@C?FEF?DGGABH@@@DGBBBA?GAI?GCAADAIAIIFIFE?DCIFHBFCH?GFDFB?GD?AHACFBI????FEIEGGB@HEEAD?HIIC
@>chr21:9741868-9741937-0
GAAGGTCCTCTGCTAACTCTATCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAAAA
+
CAEBACHCCAFADHEFBCFA@#GCGAH?FC@FFCAIIHHFIA@FIDGDEGEAEHEHGDFBG@?GC?BC@FIACH@IIGHIEB@FFBBI@D?ICAIHHF??
@>chr21:9741868-9741937-1
GAAGGTCCNCTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGCTGCAGGCTTTGGNTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAAAA
+
EIBIICAG)I@CGBBHCI?FFA?CA?ADGE@DFIEICECA@IEHABACFD-GAGB?@@?FGD@)CAB@EIBDDCDDEACH@@DFAI@BHI@FFGACCDAB
@>chr21:9741868-9741937-2
GAAGGTCCACTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGNCTGGGTGCTAAGCTGAGATCAGAAGAGCGAAAAAAAA
+
@BDGABFB;D@DD@?IGFEFIGAFAE@IGBEGIAB?C@FHCC??HBCA@CIF?EDEAEBFDA,ABICBII@FHI@IHDGHBAH;CHHAF?DFI?HHEGED
@>chr21:9741868-9741937-3
GAAGGTCCTCAGCTTAACACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTATAGTTAGCAGAGATCGGAAGTGCGAAAAAAAA
+
HH@IGFCHB@GBDFB@3E@IHFDIFG?BH@BCG??EBEAIGH?HCE?FBHID@GEIBGF@CDIIBDF@,BHFADE@I??H?CH?IGED%ABDGF@FFDBG
@>chr21:9741868-9741937-4
GAAGGTCCTTAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTTAGCAGAGATCGGAAGAGCGAAAAAAAA
+
IBIGFICF?:@H@GEGIFCFIIGDE?EFIDFBBAAIIC@II?BI?FBGIAGACIGCIFICEIGB?@FCDAHC?@GDH?IECHDAGACDCE@EEAHE?C?D
@>chr21:9741868-9741937-5
GAAGGTCCTCAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTTAGCAGAGATCGGANGAGCGAAAAAAAA
+
GCB@FIHF?CD@CDI@AIFGIE?FEICEIIFFGHC?HFHAEHFEECCHEIE@I??BCDDFEGBH@HCHCDFFCCD@I?GD@EBGAH*B@D?E?@@DBDA@
@>chr21:9741868-9741937-0
GCGGCGTACTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
CIDAEFDFAC?G?EFFBBHGHGCF?BHFAAABGH?DA?BGCAHGDAGEBAFCGCICH@HHHGFFECGFED?FAE?DDAAIG??@EE@IFC?IIAIFACCC
@>chr21:9741868-9741937-1
GCGGCGTACTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGTAGGCTTTGGCTGGGTGCTAAGCTGAGATCNGAAGAGCGAAAAAAAAA
+
CGHGB?E?A?AICCBAC?CEE@FEDAEBEAI?E?IA@?EGG?HFD?FDDDHH;@HICH?ABGDBFCFEFBHBHBIGFBBHEA4@IHACADCICIIB?@DE
@>chr21:9741868-9741937-2
GCGGCGTACTGCTAACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
DIFI?CA?C?D@@GFCIGA?C@?EEGAH@EIH?<GFIH?HHCIEDDIHBEEAAIGHIEBCFHHCCACFDF@C??HAIDB?@GABCEDDEHHCGGE@HCFB
@>chr21:9741868-9741937-3
GCGGCGTACAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTTAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
DGBDHFF?AD@@GIDH@ACIGCADCE@@DBHCF?FII@CABHFI#BBGGIBD?@A@IC??BIIA?I@GIAF?IDICEH@DGEDF@GI%GIGGGF?AECHC
@>chr21:9741868-9741937-4
GCGGCGTACAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTAGCTAGAGTTAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
BIFEFHEBHEDFDBH?@BICFECFH?@ECIA@G?CFCFDEICHB@E@H?I@IBCBEII?EBI!BHHEGFEDBC@IHH?AII@HFI?D@IADIBHEE@BG?
@>chr21:9741868-9741937-5
GCGGCGTACAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTTAGCAGNGATCGGAAGAGCGAAAAAAAAC
+
D?@AD@HIAD@?B@BEBA@DGBCBFFBD@EC@AAIEDEC?HAHH@?D@GHFEC@HGE?@F@GFCFCEADH@DCE@A?)BFCADBB?CEDCAEHAA@BAA6
@>chr21:9741868-9741937-0
TCAGACGGTATTCTGCTCACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAA
+
GCIGB??@DH&@F?@EEFAHEGHD@G@IHBDHHD?AHAB?@ICID?A@CGBFEDIFEDACBIIEFFABDBFHHAE?IAFAF?BBD?IFFE@??@HFAFI@
@>chr21:9741868-9741937-1
TCAGACGGTAATCTGCTCACTCTAGCCAACCACTAAATCTTAAGGTGGGAGAGANGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAA
+
?2EC?DFHECEI?@BBGGCCDDEIEIHHGBDFAGHF@?E@FHEE?FBAD@FCFC:H?BDDHHD?HBFFHBD?GCAFIIBCA??@BC@G@?GGAB@AHACE
@>chr21:9741868-9741937-2
TCAGACGGTAATCTGCTCACTTTAGCCAACCACTAAATCTTAAGGTGGGAGAGATGCAGGCTTTGGCTGGGTGCTAAGCTGAGATCGGAAGAGCGAAAAA
+
H@FEEG?CI@DHBCCCB?I?F,?H??CIHDIBIEAI@BBIAHHIDIAB?AHBHBDGBEEFGAFHBDBECBAADGI@?HCIE?GG1IDBEGDGGFGF@G@B
@>chr21:9741868-9741937-3
TCAGACGGTAATCAGCTTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGACTAGAGTGAGNAGAGATCGGAAGAGCGAAAAA
+
ADCA@IEBCAGA@HIBIFGE?EBHCHAHBHAD?@?@HBDB@BH??HICC?FEGEG@?HFDGBHH?@D!ABAC?CI?E@5ABFDGHHBCEA??A?CIDIG@
@>chr21:9741868-9741937-4
TCAGACGGTAATCAGCNTAGCACCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTGAGCAGAGATCGGAAGAGCGAAAAA
+
BF@BGF@IBFIFIGF@1DDGIHDDAHEEBBEABH?AGCHCHGHEIC@HGIDD@ACGAEGD?I?AHHEAE@EGCFB@ABBDCFDDDGFG@AGDDAGIBI?A
@>chr21:9741868-9741937-5
TCAGACGGTAATCAGCTTANCAGCCAGCCAAAGCCTGCATCTCTCCCACCTTAAGATTTAGTGGTTGGCTAGAGTGAGCAGAGATCGGAAGAGCGAAAAA
+
AEBG@IF?CIIDFADA9G@:AD:??AHDAEEHG9BHAHD@H?@IEDIGFCDFEICAFE?@BDAHGADDCEAFFD??ICEAHCIIHGBFIIHE@A?EFD@E
@>chr21:9742213-9742315-0
ACCACTATGTCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGAAGATTGCTCACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAATGG
+
I?@FHEBHCHA@@FIE?HI?EDDIFAAA?B@@C@FDF@?B@FIHICD?HD@GGCGD?I6@ADIICAABEGE?@EDEAGEB@CDBEAG??EA?FEAIFBID
@>chr21:9742213-9742315-1
ACCACTATGTCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGAAGATNGCACACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAATGG
+
?@GB?GGABH?@BGHDFBEDCCCBI?D?B?IE?IGCDIDE@CDA??HF@@CHHIE7GBII@AC???@D?FH?ADBHDE?DFGFAED@ACB@GGAEGBI?I
@>chr21:9742213-9742315-2
ACAACTATGTCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGAAGATTGCNCACAGGGGTCCNGATGCATCCGGTTTTGAGAATGTTAATGG
+
BB4GFFICAABGEFHCHEHEHCFGABEABHIDD?GGEFCGB@HIEHEAGHB?HG?BAA;CG@?A@IACHG=E@FID?HG@II@?CFHIHGIFD@GGAADD
@>chr21:9742213-9742315-3
ACCACTATGTCAGCTGGTGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTNTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGG
+
FAGCHFDCHFAGIIGG@IEIADAAADD?EAHDCFFI@@FICB?ECDBB?D@DEIBAHCGE8C?FB@GBH@C@AFIEDIHG@GAD?GHBCIBFCCECCGE?
@>chr21:9742213-9742315-4
ACCACTATGTCAGCTGGTGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTCTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGG
+
IE?E?@FH@CHDFD@CHHAI?@E?I@@FB?BFDFEFB@G@GBI@CDD??I?DGB?BHB?B8FH@CC?CBFDBHIDHFA?CHD@FEFICBGED?CCF@B?F
@>chr21:9742213-9742315-5
ACCACTATGTCAGCTGGTGTAGCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGG
+
?DCDE?CAFBGHHF@C?BDH@5IEBGECDDD@FG?HGEHCGGEIDFAFBF@IFHGFDDDD?CBFFBC?GGFIIDCAGHIACFB&FHHB?H?@BBDADFHC
@>chr21:9742213-9742315-0
CTCATACCACGCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGGAGATTGCACACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAATG
+
G@FD@ABIF@EHGDD@EBABFBHEHGCH?GCAEBEAFBBG?FBGA@GDBCG+C@HA@@?BBH?DIGGBBEEIDIF@GD?IEHHDCADBFDFB?AA@C@B@
@>chr21:9742213-9742315-1
CTCATACCACGCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGAAGATTGCACACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAATG
+
@DGAAEE@G?FH@EHIGFDADGFG?@C@EAEB??GCDH?CD@?@EICABE@IGBBBGFE?CDIFACFHBFAAIEGADGFEEFGDBBF?A@@BCIBEHFHF
@>chr21:9742213-9742315-2
CTCAGACCACGCAGCACTGACTGCCTTTCTGTCTAGTGTCTGTNTGCTATGAAGATTGCACACAGGGGTCCAGATGCATCCGGTTTTGANAATGTTAATG
+
EEID<DF@EFFEB?DI&I?FGI?GHAA@?H?I/GEBEHFCIEI+EH?F@DB?@@HAG?DD@DABHBCGE@AGI?EIAHA?BEBIHI@G?#F?CI@FDIC?
@>chr21:9742213-9742315-3
CTCATACCACGCAGCTGGTGTATCCATTAACATTCCCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAANCAGAAAG
+
??IFACEIIBHG@@FAIDDEHCGEB@IH@EGDCHI4H?GGHDECEIGABEI@@GCGABHDG?GHHF?BD?FHBDCEBB?A?B@GGBDC@DEC*I@GE??C
@>chr21:9742213-9742315-4
CTCATACCACGCAGCTGGTGTATCCATTAACATTCTCAAGACCGGATGCATCTGGACGCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAG
+
D@@AEEB?FEHIA@BCAGDG?BIGBHFGGCBIIB@ADBH7(@?ADBDCAHH?CADDE1FCG?BECI@DAA?DFCGAIIF@EAEEBBG?EDBGHCE@F#@D
@>chr21:9742213-9742315-5
CTCATACCACGCAGCTGGNGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTGTNTGCGATCTTCATAGCACACAGACACTAAACAGGAAG
+
??@CAG?EHFCEFECA@F4@FH@?AD?@FBHGHI@@AGHC@BE@GCC?AGAF@CDDHAFF@ED1H@F&AF@EAFDEDH@?G@B@GIHIFCC?DAA@:FEG
@>chr21:9742213-9742315-0
GAAGGTCCTCAGCAATGACTGCCTTTCTGTTTAGTGGCTGTGTGCTATGAAGATTGCACACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAATGGA
+
AEH5FIEFEDIIEGD?IHDIDHAGAFG@?BFHH@DE1FDFDAHCIIED?GEI?CBB@IHI?IAFDGABADBFGCI@FBB?C@GHHAFDFGII@BIG@EHA
@>chr21:9742213-9742315-1
GAAGGTCCTCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGAAGATTGCAGACAGGGGTCCAGATGCATCCTGTTTTGNGAAAGTTAATGGA
+
ADC?D@AH@BBACEFDHE?DADHH@ABECAFGDCEAHEB?BDDDG@DBCCDBE@CEIF-BHBAGEFIBA@?G?F@HDHEAA@?ACD5GBF.CFE?A?AA@
@>chr21:9742213-9742315-2
GAAGGTCCTCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTAAGAAGATTGCACACAGGGGTCCAGATGCATCCTGTTTTGAGAATGTTAATGGA
+
EDCGHDBC@GH@@GA?BACGDGAAFEAFD@GG@FA@IFEDB@GB@IB6DAACBCAFGFHDCI@E@CBABHD@AGH@AEABEDFAGBD?H?HIEHBEDCEA
@>chr21:9742213-9742315-3
GAAGGTCCTCAGCTGGTGTATCCATTAACATTCTCAAAACAGGATGCANCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGGC
+
??IGECEBAFCBDHIA@HHEBIAH@?FIBH8@IGEAB@FFDG?CDCDA+DHG?EF@@ABEDHFA@AB@EGHHFBDCDG@B?FEADCCHECGA)BFG@BBA
@>chr21:9742213-9742315-4
GAAGGTCCTCAGCTGGTGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGGC
+
?EBGBDB?FEDC?DGI%A@EADI@AADAE@EDGGHACHF@C?AEHABED@HA?ID?E?EEG?AEFAC?DCB@?CDADA?DIEHIG@?IDA@D?HC?BDHA
@>chr21:9742213-9742315-5
GAAGGTCCTCAGCTGGTGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGGC
+
DGEAIDDFBHG@@DCA?H?FDHACE?H?G@HI?FBI@FF?DHFEIDIIHBBF?@EDHIHFEDAEDIFB?AI@B?C@IBBDIFBAABEHEBAGECCE?GC@
@>chr21:9742213-9742315-0
GCGGCGTACAGCAATGACTGCCTTTCTGTTTAGTGTCTGTCTGCTATGAAGATTGCACACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAATGGAT
+
@DFIFEDADDDAFIIA?HEGB?A@EB@?HII@F?FHGGH?6BFEFCIAF?CAB?A@HGI@BDGI@DCIFIBHDFCAI?DCF?AGICCCAGHACIHG@@AC
@>chr21:9742213-9742315-1
GNGGCGTACAGCAATGACTGCCTATCTGTTTAGTGTCTGTGTGCTATGAAGATTGCACACAGGGGTCCAGATGCATNCGGTTTTGAGAATGTTAATGGAT
+
?8GCFA@AB??CEH?F?BIBIIF5HHCFFHEACG?DHAHG@ED?AEEBIFBEEFBFIIHDHAE@?HHDCB?DIBDB5A@AHCB?@AAH@CIBHIIEDGGE
@>chr21:9742213-9742315-2
GCGGCGTACAGCAATGACTGCATTTCTGTTTAGTGTCTGTGTGCTATGAAGATTGCACTCAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAATGGAT
+
@G?DABHICHBAIECHBDFAI=IGB?BDABAFDG?A@FBD@AA?BHBDDGEA@@EF??=@AGIAHIGFBGFDC@F<FDHCGA@GGHHFDG@BCGG?AHGA
@>chr21:9742213-9742315-3
GCGGCGTACAGCTGGTGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGGCA
+
BE?@CFIEI?DHDFICEIF?FDGCFIAGGG@ICH@?@@EBBIAFH@EHBEI?EGFBCB@GBBBAGBCE?DHD?CFADAFHEEBCCCEA?CAE?CBGIG@B
@>chr21:9742213-9742315-4
GCGGCGTACAGNAGGTGTATTCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGGCA
+
CI@GIDAG?HH,7D?BDGI@6GDEEBDCHE?@IHA?EBFEA@HECAH@F@?EHGA?GCF?GHHABCB@EABBIAH?FBFA9DIEIEDDE@BD?DGAAIEF
@>chr21:9742213-9742315-5
GCGGCGTACAGCTGGTGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCTCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAAGGCA
+
BFA?IHFDFI@AFCEFAFIHDIDFE????GEDEB?GIAA@?IHFHAEDEHGE@GH5AC?DAF?ECHFA??IGFB?C@@?HCA@HC?D@ID%E@BACIAAE
@>chr21:9742213-9742315-0
TCAGACGGTAATCAGCAATTACTGCCTTTCTCTTTAGTGTCTGTGTGCTATGAAGATTGCACACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAAT
+
EIFFEFIECH@D@@CCEA@+E@FCA?DEFDG:FGCCA?GEIFDIB3?DDEA??IFCHDF@IAEHHCHIED?HHC@CHGBCGBFAGAG??A@EB@BGGDAE
@>chr21:9742213-9742315-1
TCAGACGGTAATCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGAAGATTGCACACAGGGGTCCAGATGCCTCCGGTTTTGAGAATGTTAAT
+
GBDHBB@CI@HCFBB@BBCCEADIDBBHBB??GHD@B?CGAE??IIEHGIG?DFCA?@FBI?AC?BB@EHGEFCHGBE;C?F@IAAAEHIC?GIICBIG@
@>chr21:9742213-9742315-2
TCAGACGGTAATCAGCAATGACTGCCTTTCTGTTTAGTGTCTGTGTGCTATGAAGATTGCACACAGGGGTCCAGATGCATCCGGTTTTGAGAATGTTAAT
+
HIIBCB?G@CCHFGBEHABD?AEIFHEADHECCCBC?@?H@I@?CED@F@?DDCABDH??FACC?GICHIAG@EA?@DGG?CADE@AEFGDIBFACB?EH
@>chr21:9742213-9742315-3
TCAGACGGTAATCAGCTGGAGTATCCATNAACATTCTCAAAACCGGATGCATCTGGACCCCTGTGNGCAATCTTCATAGCACACAGACACTAAACAGAAA
+
EDF?FGBC?EBF?H@FFIH/AEA@EID@3@AH?AHBIEAA?AB?CEGGAFIAHHIFA@DCHBHEG.I?CHHE?FH@?GFCCDICDCDI?IFEIB??DCCC
@>chr21:9742213-9742315-4
TCAGACGGTAATCAGCTGGTGTATCCATTATGATTCTCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAA
+
E@D???I@H?EBAGEDBIACBFCIHABGI?65BCIBGI@DG@FDEE@GC?ACD@ECAABCD?AI?F?HC@HBGIEF@CDICFEF?HFHBDGG?I@EFBGB
@>chr21:9742213-9742315-5
TCAGACGGTAATCAGCTGGTGTATCCATTAACATTCTCAAAACCGGATGCATCTGGACCCCTGTGTGCAATCTTCATAGCACACAGACACTAAACAGAAA
+
AGFAE?@?@I@?H??GACEFCDEB?ABBI?EBHG@CCFBFAFIFEABAF@GBGB@F9HBHBAICH@HECDHEAGF?@EFFCFFHCHAAGBI?DHIFDGB@
@>chr21:9751339-9751444-0
ACCACTATGTCTGCAAAGTANTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGTCATATTGGTTGGTTCCAAGTCTTTGCTA
+
ACHEF?BBG?H?E@A5EGAC0DG?IFCBBBIAGIHFAIDDHEI@BGAA?CFCHGBEECIGGGFG@?B@CEG@FEH?F8GGDFFC@CIH?FD@EIGG@?B?
@>chr21:9751339-9751444-1
ACCACTATATCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGGTGGGCATATGGGTTGGTTCCAAGTCTTTGCTA
+
B?EDIIIG'BH?HGIGDCG@?AGFAEIBC@ECBFDG?DHBGFI?FFBA@B@EB@DBHBF?EB@@C?H,FFBAGGIH@FGA?IDCHGII?DBFBECGAGB@
@>chr21:9751339-9751444-2
ACCACTATGTCTGATTAGTATTGCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGGCATATGGGTTGGTNCCTAGTCTTTGCTA
+
?GHEIDEC?G@EC$(@@BF@CH.AC?F?GHFCDF@GGGECICBHFIC?I?@AIBGFAEG@FBEGGCDIBFE@??AA@?FH??BC?:?C4FCFB@B?IBHF
@>chr21:9751339-9751444-3
ACCACTATGTCAGCACTATTCATAATAGCAAAGACTTGGAACCAACCCATATGCCCATCAATGATAGACTGGATTAAGAAAATGTGGCACTTACACACCA
+
?IACA@A?HAIGBIFIFC?@ADBADACDFC?CBHFEDIAGGFE@HFGFA@@@HBGCGACECGDFDGFGI@BH?HADF?E?CEF@G?CF@HH?H@DGBFEE
@>chr21:9751339-9751444-4
ACCACTATGTCAGCACTATTCANAATAGCAAAGACTTGGAACCAACCCATATNACCATCAATGATAGACTGGATTAAGAAAATGTGGCACTTACACACCA
+
C?@H?FDEBB?H?IBDHBBGHA7GCC@HGB@E@GD@BHB?GHCDFABFDF@G)H?DBD?H@AFI?GAHIBHGCFI@FGGDBBEFCGDBHG@D?C?DAGB@
@>chr21:9751339-9751444-5
ACCACTCTGTCAGCACTATTCACAATAGCAAAGACTTGGAACCAACCCATATGACCATCAATGATAGACTGGATTAAGAAAATGTGGCAATTACACACCA
+
BDDBF?:@ICDDFAE@FD@AIH.AI?EBCIF?@AIFIBACHADED?EE@GHACCAE?HAFADCD?EHFCGIF?GGDEEGFHI@EBHGAB:DCGEIC@IAB
@>chr21:9751339-9751444-0
CTCATACCACGCTGCTTAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGTCATATGGGTTGGTTCCAAGTCTTTGCT
+
?ADGEFHBCGAEG@/>?DFFGEDECBECE@AFGDC:IEHGECBIDIA@AEFDGACHGEBEB?@I?CAABAAEDIIHCDD@?HIA?DIF@I?ACAD@ACAC
@>chr21:9751339-9751444-1
CTCATACCACGCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGTCATATGGGTTGGTTCCAAGTCTTTGCT
+
GB?ACICEBFFCD?EBC?B?CF@@IF@EHD@IDIEEGBEIFIFIFACGDADBBEEBHGI@DAHDGB=II@BAA@IEAGC?DA@BHCGFDIDA?@G@CBFC
@>chr21:9751339-9751444-2
CTCATACCACGCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCAATGATGGTCATATGGGTTGGTTCCAAGTCTTTGCT
+
HIGGIBGDEFD?@EHA?GE@D@IA@AHGI@@BE@DEAGEIBBBF@F@@@CCEGGHIAD?EHIIC?%F@IAIBEG?D@HD?AH?@B@@IAGEBBEIEAFGA
@>chr21:9751339-9751444-3
CTCATACCACGCAGCACTATTCATAATAGCACAGACTTGGAACCAACCCATATGACCATCAATGATAGACTGGATTAAGAAAATGTGGCACTTACACACC
+
IHBG@GDAIICBBECH@BCFGEHEG?D?HDE+B@?FFCG?BE?ID?A?@BBHEDBBIDD7@CCCF@CE@F@G??GDBD@AHB?B@BGCCGGAEACHEADA
@>chr21:9751339-9751444-4
CTCATACCACGCAGCACTATTCATAATAGCAAAGACTTGGAACCAACCCATATGACCATCAATGATAGACTGGATTAAGAAAATGTGGCACTTACACACC
+
EGAAIEIC@EACGG?@ABEI@FIH?BAEAACAIEEAIHDCDE?FHF@GBABC:HI?ADD@ECEDICAIEDIC?IHFEAGDGDFH@IDGAAEAHGGHEGAC
@>chr21:9751339-9751444-5
CTCATACCACGCAGCACTATTCATAATAGCAAAGACTTGGAACNAACCCATATGACCATCCATGATAGACTGGATTAAGAAAATGTGGCACTTACACACT
+
FHCGB@IAA@DDIFDDI?BBAAFFBEBEBI?FGGIIAB?D?HA4BHG?AFB@@IG?FAGE*EGBF@EACHDCCADFFBFB?DCG$?ECHH@HB?E@CB?#
@>chr21:9751339-9751444-0
GAAGGTCCTCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTGTATCATTGATGGTCATATGGATTGGTTCCAAGTCTTTGCTAT
+
FIHGCBHHHHHEI?DBF@G@HIA?C?DBF??EC@CAEA?@DFFACID??HCFFBADF3CB@EFFAIE?CFHEDDF@AA>@FFA?BBB?IHHGDBGEIGCA
@>chr21:9751339-9751444-1
GAAGGTCCTCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATAATTGATNGGCATATGGGTTGGTTCCAAGTCTTTGCTAT
+
CGD?DF?IGIHCCCCHGH@%AEIHEF@BCB@EFCH@E?DGEH?AIA@E?@I@D@AIBDEBB1H@?DIF(BE@BCEIICGIF1@I@G?EAE?IE@CHBBAD
@>chr21:9751339-9751444-2
GAAGGTCCTCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATNGGCATATGGGTTGGTTCCAAGTCTTTNCTAT
+
BDED@CGDAAAA??GB?C@DEEDCIGHH@CF@EDDDEFGH@@AFA@IHCB?ADD@FBDID??CCEABB.DDEDHCBADDFCCDDDDGCEEC?FFG9IAIA
@>chr21:9751339-9751444-3
GAAGGTCCTCAGCACTATTAATAATAGCAAAGACTTGGAACCAACCCATATGCCCATCAATGATAGACTGGATTAAGAAAATGTGGCAATTACACACCAT
+
?AGCHDDAIADHGIG?FCH;GADCDG?EDCADHEGI@?HF@CD@B@F?IH??AFBHGI@BB@C?FHAACDHIA?I@@?IC@ICFIGCH1CBBC?E@B@BA
@>chr21:9751339-9751444-4
GAAGGTCCTCAGCACTATTCATAATAGCAAAGACTTGGAACCAACCCATATGACCATCAATGATAGACGGGATTAAGAAAATGTGGCACTTACACACCAT
+
?@D??DHD@ECHFBGDBEIFG??DF?II@FDHBEDACFCH@BEEEA@HBF?@BGIFCC?@GCGF?FF?2EEEIGB@AEIGBGHGHHAH?GI@I@E?G;HF
@>chr21:9751339-9751444-5
GAAGGACCTCAGCACTATTCATAATAGCAAAGACTTGGAACCAACCCATATGACCATCAATGATAGACTGGATTAAGAAAATGTGGCACTTACACACCAG
+
@CHEI8HEF?@CBFBHBAGAAAEFBE??HGBBFDACHFCDHABAFCFBEAAG@F?CHFGGAHEAHHABBEE@HDEACB?AFEDGA@EB@EFEEBH@EC@4
@>chr21:9751339-9751444-0
GCGGCGTACTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGTCATATGGGTTGGTTACAAGTCTTTGCTATT
+
GCHAGCDFDIDBIICFGEH?CBHI?HECHBEHCAGHFBDIECAEB@GFAICIDHCCBCADCCAE@CBGDEEGEG?AE?ICHIH?+IBG??BBIDHCEC:@
@>chr21:9751339-9751444-1
GCGGCGTACTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGGCATATGGGTTGGTTCCAAGTCTTTGCTATT
+
DDHDEI?FHBFHC?FEFEH@AGAA?IAGCDIHBHBEIA@CEHHHCCABBID@IECD?FHDD@IHE?AHAAECGCC?D??@E@ABCB?A?BCFABE@E?A?
@>chr21:9751339-9751444-2
GCGGCGTACTGCATAGTATTCCATGGTGTGTAAATGCCACATTTTCTTAATCCAGTCTATCATTGATGGGCATATGGGTTGGTTCCAAGTCTTTGCTATT
+
AH@HA@@EH?HCBGHHACF@IIIF@EABDBBD@!AAA4@BIC?GD??E@CGFFCCCEHGFF?DHG?IEFEDCGBCE?A@BBFI@?EAIGGBBEFHHFAEF
@>chr21:9751339-9751444-3
GCGGCGTACAGCACTATTCATAATAGCAAAGACTTGGAACCAACCCATATGCCCATCAATGATAGACTGGATTAAGAAAATGTGGCACTTACACACCATG
+
H@EF@D@C?CEDED?GFHBHHBEBBCHDDGHBFHEGFI@IEDDDG@BGCACBAACB@H@CAE@BHDDEG@?BE?BH?DEIEIG@EI?AGFDI?@AGADCH
@>chr21:9751339-9751444-4
GCGGCGGACAGCACTATTCATAATAGCAAAGACTTGGAACCGACCCATATGACCATCAATGATAGACTGGATTAAGAAAATGTGGCACTTACACACCATG
+
H?D@E@;HACGIGFEGAIE@BFFF?CHDIB@GD@ICGEIEH.EGBGGEGFCED@DGIHD@@HFBEF?BHAHBAGFGG@IEAI?FFD@@?BI?IHEEEBAE
@>chr21:9751339-9751444-5
GCGGCGTACAGCACTATTCATAATAGCAAAGCCTTGGAACCAACCCATATGACCATCGATGATAGACTGGATTAAGAAAATGTGGCACTTACACACCATG
+
EHAAIHFIIEGGGCIHI@HBF?I?CDHDFHI$BADAG?DCH@CDDCH?HCCHCBE@D2HHC@II@@?BDAIDAIFDHCGHB??HFFIG@BDDHAFD@?EE
@>chr21:9751339-9751444-0
TCAGACGGTAATCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGTCATATGGGTTGGTACCAAGTCTTTGC
+
C?I?EE@GI@CEAAHECAEDBEHFFDBF@@AEEGIIDAD?E?IGFEBGGDC??E@AFI?D?FAIFBFFBD@FAGCGIFBFA@BCDC?)D??%IABD?DHA
@>chr21:9751339-9751444-1
TCAGACGGTAATCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGTCATATNGGTTGGTTCCAAGGCTTTGC
+
IGACDBGHDGIGIFGG@IBEGEBHA@HEC?DI@??IBG@HAII?CBDEEICIE?@GED@EBCFAHFECCF?BAFDE?C@4ED?BIDHBCG?G?"IFFICI
@>chr21:9751339-9751444-2
TCAGACGGTAATCTGCATAGTATTCCATGGTGTGTAAGTGCCACATTTTCTTAATCCAGTCTATCATTGATGGTCATATGGGTTGGTTCCAAGTCTTTGC
+
@EIEDCAIEHIHD?F??AHI?H@EBI@I@AGICAGG@@DI@GEEFCCGACABFF@@C@BEC@BHAFBGEBIFC?GIAIIFD@FB?ICAAC?C?CCGHGH?
@>chr21:9751339-9751444-3
TCAGACGGTAATCAGCACTATTCATAATAGCAAAGACTGGGTAGCAACCCATATGACCATCANTGATAGACTGGATTAAGAAAATGTGGCACTTACAGAC
+
?EB@DBCIBC?HAG?GAHBHEEIDAGGCGCFDBFDH@A%CF0@5ICCFCC@BG@@?BGB@BA=FHCAGDCHAIFGCB?DBHH?HGHIHFBIH@BIFE#G:
@>chr21:9751339-9751444-4
TCAGACGGTAATCAGCANTATTCATAATAGCAAAGACTTGGAACCAACCCATATGACCATCAATGATAGACTGGATTAAGAATATGTGGCACTTACTCAC
+
AHEHEDHA@ADDFEECG*HDEBGB@E?BCB@CBFGECD@DGA?D?EHGFIAGHG??A@FGB5??DFFDCHCFGI@FEA@?BB0CHAAFH?BEDHDF4?HI
@>chr21:9751339-9751444-5
TCAGACGGAAATCAGCACTATTCATNATAGCAAAGACTTGGAACCAACCCATATGACCATCAATGATAGACTGGATTAAGAAAATGTGGCCCTTACACAC
+
EEDED@DF3DEI?HFAEIIAHDHEA7BHGIBFEHA@BHFCIGBCGHI?GABIHA?A@@C@@F@F@EC?FAHFHF?D?DHBEDE?IDFDH@2EFIGFGCEB
@>chr21:9755088-9755283-0
ACCACTATGTCTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAACC
+
?GBDEIB?BIGCCBBIFAA@BBGGBDHHFIABEG@IGBHFDBHDHCAGFIGADAEFBIDD?D?@FFEE@G?BIFEHCE@?FGEE@BAFD?EIBBB?DDAF
@>chr21:9755088-9755283-1
ACCACTATGTCTGCAGNAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCGAGCTGATCAATGTAGAACC
+
@I?C?B@F@DHCEDFI0CHD@FFGHGHDFEAHFI?@@ICHFB?HFBDI@F@D@IIEDC@FAEHFIEGFC@ADCC?GAF@B%HACEH@?ADDCEDB?AEIG
@>chr21:9755088-9755283-2
ACCACTATGTCTGCAATAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTATCTGTTATTTCATAAGGGTGTATCCTAGCTGATCAATGTAGAACC
+
ICGAC@@F?HG@?CB8H@AD@FEGH@DIF@FBIBDBGII?IAFDBFEAGGICC?F#BBC??HI?IHCAEBH=IAFI@BBBHHDD?FCCDI?EI?CIF@DH
@>chr21:9755088-9755283-3
ACCACTATGTCTGNCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATACGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCACC
+
@FF?ABAHED?I@<CIHGBCI?BFF@FG?CG?BH?@B@ACGGFC?GF?F@DAHI@F?AD?@G?CBFD@IFGGFE@ACGHIBH?B@FIDHBBF@??ACE@G
@>chr21:9755088-9755283-4
ACCACTATGTCTGCCGGCACAGCACAAATAAATACCCCTTGTCTTGTCACTGAGGAAATATGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCACC
+
AD@IBIDI@AG@DI?;IHGEECBHDGEEBD@ED/EC@C@AAEBB@GFHD@IEBEACI??EFFD@A?A@DFHCBHF?BHCI@GGAHEE@?D?AF??EGBI?
@>chr21:9755088-9755283-5
ACCACTATGTCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATATGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCACC
+
G@GIDF?CE?BDEC?ACC@EBCHIHDGIEBCGBFE@I?FEBDHEDD????HAHGBABFCBCBG?EAAIFGEIDGHAEAHA?FAGFA4GGEDDC@?ADA@B
@>chr21:9755088-9755283-0
CTCATACCACGCTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTANCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAAC
+
IIFFIGAFFGFFC?HGID?FBDG#?CGBHADC?CFAHDI?FGCA@A?F?@GADH?F*@FG?DEEAIBECAFFEGHCCD?FGGH@GHFCIA?HBE?A?HA?
@>chr21:9755088-9755283-1
CTCATACCACGCTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATCAGTGTGTATCCTAGCTGATCAATGTAGAAC
+
AE?FGGHIBCBBGHBCDEHC@D@?HCDCDEGE@BFHHGAH?EFDEBF@IFGEFABGBIFAC@CHHEFHG%DECG@IECDCIF?GDA?BDGHD@GDE@FDH
@>chr21:9755088-9755283-2
CTCATACCACGCTGCAGTAGCCCATTTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAAC
+
HDGBII?AFII?C@HEF?E@IGCGC"HHBGB??@H?FGHA?BHIIECBFDCAHEGC@IHAE@FFAE?EBI@AFBCBAAHEGG?F?D?@BDA@IAIGACIB
@>chr21:9755088-9755283-3
CTCATACCACGCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATACGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTNAC
+
@C?AIICCDCCGCFIIFEFEEE@BG@F?F@GDGFGBEFHDH@BFDAIHCIAB@EGHIBDDH@G?H@BFIBGG@IEHEBEACACBCEEDFDD+CFC@I9A?
@>chr21:9755088-9755283-4
CTCTTACCACGCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATACGCAGTTGGGATGACAGTTNAGGTGAATGTGTGATTCAC
+
BII#@DABI?BC?DB@A?C?BABE?DACDED@EEFC@CCBIEFA?DE?F?IFFHIABAHHACBGB?F?C@BCHE??GCEC1AEHDDE@AHBB@FEIBA@A
@>chr21:9755088-9755283-5
CTCATACCACGCTGCCAGCACNGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATACGCAGTTGGGATGACAGTTCAGGTGNATGTGTGATTCAC
+
BHCHB?H?HEBHGDAGH?A?A&?CA?ICHECGIAHAIAGHGBBG?@HGEHA?HHH@?DEDBFGE?AGGEDDEAF@EF?FAGI?DAC.G?DGECFEAIAA@
@>chr21:9755088-9755283-0
GAAGGTCCTCTGCAGTATCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGCGTGTATCCTNGCTGATCAATGTNGAACNC
+
BHAIBGGCIGFAHFCBD2GICGEIBI@IHICDCHFIIHEFFCG?EGEG?ICFD@IAFIE?AGAIIDFFBB;EF?BBGEEB;D?EI?DBIGGAC7@BHC6A
@>chr21:9755088-9755283-1
GAAGGTCCTCTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAACCC
+
EH?AEBDBAGGICD@DFGECIABHBIBI@EEFGB@HF?BA@FD@EIGDDI@AGFBFGDGC??CIAHA?FIB?C'D@CCD?I?A@D?AGEEIIABI@DHI?
@>chr21:9755088-9755283-2
GAAGGTCCTCTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAACTGGTCAATGTAGAACCC
+
EGAEGCGCBCADEGIBFGGDAFDG?AFBEICEBIIFGGH?DHD@BHH7AIE?DI??AHFDGDD@CEFIBBBHDCEAEDDCH3CBF3IHBFDIHICBA?DF
@>chr21:9755088-9755283-3
GAAGGTCCTCTGCCAGCACAGCACAAATAAACTCCCCTNGTCTTGTCACTGAGGAAATACGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCACCT
+
DBH@ICCAHIBEGI@IGI@FHIF?C?BDFEF'@IIDFA(?AC@IFF@BAG@IHCAGA?BHFBFHCGDGCIEA?D?A?@EC?ABAIA@E?C@BB?4@EGGD
@>chr21:9755088-9755283-4
GAAGGTCCTCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATATGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCAACT
+
ID?BICGFEF@EI@DHIBCCCCDDCBID?EEBGFAIAGHFEC@BIGD@@AFCHHFFFGIHGDEAI?HIA@FEBCD?AEHHIGBIAIAIDC@BCF??B<GC
@>chr21:9755088-9755283-5
GAAGGTCCTCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATATGCAGTTGGGATGACAGTTTAGGTGAATGTGTGATTCACCT
+
IFADFBAGHBFI?GABEBFADCFHAHGEBGADFEF?CA?IIGBHHB?GD?HGABCIDACEFE?BGH?A@AIAIH?FEG/E?FIABI@@EAA@BE??C@EF
@>chr21:9755088-9755283-0
GCGGCGTACTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAACCCT
+
'CFADFHC?IHEEBEHA?EDG??C@B@CBCGABBAGGED?A@?@GFHF@CFI@IBDHFDDDD?HHIFAGBDGAH?IDHA??@?GGC@GBCIBIGFGA?G?
@>chr21:9755088-9755283-1
GCGGCGTACTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAACCCT
+
ADIIB@?D?F@AGEBDH?@E?HD?HB?D???HAHGCAEDHAAGDDDDFDA?EIIG?GA?CDI@FAEEHFFHIGD@F?I??BB@GI?BCFBDIEAFHIEF@
@>chr21:9755088-9755283-2
GCGGCGTACTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATNTCATAAGTGTGTATCCTAGCTGATCAATGTAGAACCCT
+
I?FDEIAIGBC?FB@EHIA@ECFBHEBC?@D@IAIC(H@DFIG?E?BA?HFHE@ABCE??D"BE@DDA@H?BI?C?ABIFCFAEHGAECD?BFCDI@FBH
@>chr21:9755088-9755283-3
GCGGCGGACTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGTAATATGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCACCTC
+
FB@IFF1GGAGDI?HB@DDGHCI@ADI5HCIBFAH?CHAI??CF@HB?EBHDD%@AIBBEEBACIGDHF?HDDHCFCFCGC?E?IF@@BCCIH@CHBGCF
@>chr21:9755088-9755283-4
GCGGCGTACTGCCAGCACAGCACAAATATATTCCCCTTGTCTTGTCACTGAGGAAATATGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCACCTC
+
DAIFIACG@EG@FD?IBAGHI?DC?@CC>CC?EA?AGEH?EI?DICDDEG?F@DGCAGCI@DAE@C@@G@EBGIBICGAGIDGDIDHFCH?FHA?B@A@@
@>chr21:9755088-9755283-5
GCGGCGTACTGCCAGGACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATATGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCACCTC
+
F?ADDFFGCCBFCGI/DEBCAIEH?EAHBFBDGEBFHAFDIH@?GFDAEHABACA?GEGD?@IBEBIH?AH@IBGGCEGBCBB@IF@HDCEGEECHC?IF
@>chr21:9755088-9755283-0
TCAGACGGTAATCCGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGGTCAATGTAGAA
+
AEDA?G@DCCIBF+HEIAGGF@IIFG@@CFG?A?@BCB@ECHBEHF?FDIICD?GGI?E@GCC:E@EAA@E?IF@GHDH?DGHIBEID;IHH@?B??G5D
@>chr21:9755088-9755283-1
TCAGACGGTAATCTGCAGTAGCCCATGTGATCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAA
+
FABDGB?A?DDFEHDCEBDGB?IGFG@BAFG@F?EHIG?GEBG?GEFBFBG@FHBDIIHEAECCDHDIB@HD?@@GE?HB@ADBC@@@@@C@B??BIHFC
@>chr21:9755088-9755283-2
TTAGACGGTAATCTGCAGTAGCNCATGTGGTCATGGGAAAAATGAGTAGTTTGATTAGCTGTTATTTCATAAGTGTGTATCCTAGCTGATCAATGTAGAA
+
B+@<BDHHEBBIBD@FHHA?HE1HDDCGG8?EEHABFCAGABH?DCFICDIGHCBBBDD?GDCGCI?CGDBAIHCHGEGEFA@DAEFIG@ACIDIEFIFA
@>chr21:9755088-9755283-3
TCAGACGGTAATCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATACGCAGTTGGNATGACAGTNCAGGTGAATGTGTGATTCA
+
@DGAHBBI@CFD?CAFDFAGEFHIDFBAD@EABCBGC?@@G?GGEF@HFDIEGBCDDCGBDB@EAECIE??:??@E@@DG/FE?AEHEIHGHB?HBGEAI
@>chr21:9755088-9755283-4
TCAGACGGTAATCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGAGGAAATACGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCA
+
GEGCFIGH@HBFBHHDBEEF@F@AAHDFH?FIHF@@AD@HFEEF?D@I??DHEEIDA?AAHCIBADFAGFC?CBDGF?@DCHFD?@GD??@EDCBCGGGD
@>chr21:9755088-9755283-5
TCAGACGGTAATCTGCCAGCACAGCACAAATAAATTCCCCTTGTCTTGTCACTGATGAAATACGCAGTTGGGATGACAGTTCAGGTGAATGTGTGATTCA
+
B??IBA?ADCGCECG?EHBBDFFIB@@GFCD?IGAFEADC@@GECDH?CAFECHF#ADB@?GAF@FGHGFEHH?CGEDDI?G?F@BDFIGD@AID?FGFI
@>chr21:9769008-9769192-0
ACCACTATGTCTTCCCTTGAAAAGTNTATAAAACTCAATGAGGAATTGATAACAAGAACAGCGTTCCGGTATCAATAAGAGCTTAATGATCTCAAAGCTG
+
?IDEBBDGBC?GBCABGGGEH??E@,FIHB@FFGG@@CDFGFCD@I'EDAEEBDIIEC?HEH'??G@IDBFB?H?1AIHCGIE@AABBHG?IAEDE?GEG
@>chr21:9769008-9769192-1
ACCACCATGTCTTCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGATAACTAGAACAGCATTCCGGTATCAACACGAGCTTAATGATCTNAAAGCTG
+
BEAHB'?HFBA?ED?BGBFAHFAFCBCEF?CDFDI?EGH??HIHDAAFDCEAH4DBDD@@CHDC?DD@HHIDDGEHI'IFF"@C?HGB@EG@4?FAFFFG
@>chr21:9769008-9769192-2
ACCACTATGTCTTCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAAAAAGAGCTTAATGATCTCAAAGCTG
+
FACDB%DIDDHCABEI?HFDAAGEDCGFIEFGFBGHIIDDIAICGABBCCIFI@HA??AGDCE@?AEFHFF?CEF7CH?EGDI@CC@HBIBCG@GHAFGC
@>chr21:9769008-9769192-3
ACCACTATGTCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGTA
+
BE@A@ECEGGHBCH@FD?DAF?IB?HBAFB@F?AG@@HHGAGAH?I?H@DG@DIBGC?IGACAFHEF?DG?DC?B?CDB?@FFAHH@?FIDDHCAH@CBI
@>chr21:9769008-9769192-4
ACCACTATGTCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCAAGTCTTTTGTTGCTTTCTTCTTCCTTCAACCGATCGGAATTGAGCCTTGTA
+
HDBB?AGDAHGHFFFIDDI@A@E?I@BI@IFBEE?@IIAE@AGGICDF6AAHICICADIAGDEAEADE@D?IBEGCIBD!E@HDHICEFGBIHFGDEI@?
@>chr21:9769008-9769192-5
ACCACTATGTCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTACCAGTCTTTTGTTGCTTTCTACTTCCTCCAACAGATCGGAATTGAGCCTTGTA
+
GFHHC@AHBDFIHDEBI??FIIACHA?GF@?AGIB?CGDHCABCFC*AECEEHGG@GCDCCCB@@A?1?G@@BI#HEFCDC@DBAEBBC@@@?IDGHH?A
@>chr21:9769008-9769192-0
CTCGTACCANGCTTCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATNATCTCAAAGCT
+
E@F&GDFFF3HDIDBIDAIEEIFD?F@BCAAGDAAGIEFFD?A@DCAA@AG@DDHFIHIEDGAADBCAD@H@FEHIB@AAH@FE@DIC1FIEECC?EF@?
@>chr21:9769008-9769192-1
CTCATACCACGCTGCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGAGAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGCT
+
DHCAGEIFDCFEIE@I?H@GC@@EGDGADCB?DC?CIADDHFA@IADHE@+B@A?FFHAICEA@D@AHHEADEI?G??A@HIIGADIH??HEEDHEGIDB
@>chr21:9769008-9769192-2
CTCATACCACGCTGCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGCT
+
IIHDAE?GGBGAED@HDBE?GA@AHEDE@BFCBCAFGBBBC@GGDG?HFGFDEA?EE@GFBBBF@CDF?GIIDIDE@DFGEHBEBDGIEHHGF@ABBH?B
@>chr21:9769008-9769192-3
CTCATACCACGCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTGCAACAGATCGGAATTGAGCCCTGT
+
A?E@?E?GIAH?!E?BB?F@HGIBCF?BGFB@CH@GD?FIB@CD?E@@?II@F?A?BBCB?@DCDAFCA?CDD?H-GHE?IDGCF?CACI?BI?G@*DHI
@>chr21:9769008-9769192-4
CTTATACCACGCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGT
+
DB*?CGHAG?IBGG?IBEACD?CFH?BAIIEH?G?EHG@D@EE@?GAEA?H@IAE???EA?DGHFBD@HDEDFCHFFIB?H@AI?EBIGBH?AHDIAHCB
@>chr21:9769008-9769192-5
CTCATACCACGCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGT
+
GB??D?IFHAFBFE@HIEC?HHI#BAACDFCIGG@D@CHC@?GGG@IE@GBIFHDGCI@HEHIED?G?CEIGCHHCGC@CHDCHIC?GG?EDDBDHEEI@
@>chr21:9769008-9769192-0
GAAGGTCCTCTTCCCTTGAAAAGTATANAAAACTCAATGAGGAATTGATAACAAGAACNGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGCTGA
+
CEAFBGGD@GBE@?C?B@CFCBCEFHD+HGIC?A?F@ED?AGDCAEIEBD?EFGII?B5@ECFBHIIFHFDGEBAIAEFCDFHA@?IIAHGGIFFFABGF
@>chr21:9769008-9769192-1
GAAGGTCCTCTTCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAACGATCTCAAAGCTGA
+
EDDAA?HCBDAGBFHCGBFFBA??GEDDAH?ECBBCADBEAF?F@GAB?HHD@DGBDEHHBCHF?@BAAEB@EC?IBICID?BHH#I?BIFHB@AC@BII
@>chr21:9769008-9769192-2
GAAGNTCCTCTTCCCTTGAAAAGTATATAAAACTAAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGCTGA
+
GD?A2FDFC@@C?@EF?@?CAIHDFDAG@IBB@G;ECEIBADF@GAFIAEBDIBG?@D?IAEGF@EAB?DD@BA@GG?IGIFEFDAHHDEEBB??AGCEE
@>chr21:9769008-9769192-3
GAAGGTCCTCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCGTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGTAT
+
AIAC@HGHE@?EDE?D??HHIFAD?CGHFHCCD1GAGAIGFFGG7@@FFBF@CEHFAICAEI@A?GH??IHGB@F?GIG?GF?FIGD?IGDA@B?I?CDH
@>chr21:9769008-9769192-4
GAAGGTCCTCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGTAT
+
?@DHFCII@GGHFFIGC@DBGFBI?HFDCBBE@IBBGF@BEECADA@DAI?ACGACBIGFDHFB@FDCDEHGFI@HA?HHGGHGGCIACCCFEAGIF?@H
@>chr21:9769008-9769192-5
GAAGGNCCTCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGTAT
+
B@FA?1BEGCHDICAGAIF?IEGGHE?BC?BFDB@GEF??HGH@BFBHGEAFH@HA@HAEGFGEBA@@AC?EEGAD@FGI@?D@FIDBC?FCHAECDFIH
@>chr21:9769008-9769192-0
GCGGCGTACTTCCCTTGAGAAGTATATAAAACTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGCTGAG
+
@EGEI@GCABB?GG@@DG>IFIB?CIABIF@AIBII@EGGHHHCA?ABIBD?IGBFAGFICFF@IAH@HI@AGIDAIAEFIHIBF@?I@IG?AD@GCHDC
@>chr21:9769008-9769192-1
GCGGCGTACTTCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCCCAAAGCTGAG
+
BAA@D@ECCDHE@ACAAI@EEHIF??EB?GHID?BHHG?CDFGFIHF?BEDG@@CFAG?@DGA?DGDHCGDHC@HBI??@AFF?DICE?+DH@I@BIFHC
@>chr21:9769008-9769192-2
GCGGCGTACTTCCCTTGAAGAGTATATAAAANTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCTAAACGCTGAG
+
EFICFCFEFGCFBABCIBD)IIBGGF?DDGB+AICF@IABAHG?EFEEGFEA?EED?@?EGH?BDAEFBF?I@HHBEAI?HGH?CG?FB@'DD9IEFBEB
@>chr21:9769008-9769192-3
GCGGCGTACAGCAGTCACTCTAGACTGATGATCCAATTTCAGCTTCCAGTCTTTNGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGTATT
+
GFFGHCCCE?IIGDDD?3@IDEGBHA?@@IEB<?CEFHAC?FFFBDFCDHHCCB2EIHBBC?BA?IFGECEEFA@BFD@HFHIAGD@?AI@@BHABCD?E
@>chr21:9769008-9769192-4
GCGGCGTACAGCAGTCAGTCTAGACTGATGATTCAATATCAGCTTCCAGTCATTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGTATT
+
E@AAIHFEH?FCIB@HA@?EIAG?DBBBGCGECDCCI+AEFFGEE@IDEBH7BGBIGHG?F9?ECEEC?DAFBG?CE?G@EG:?DCI?DFBI?FI?GDF?
@>chr21:9769008-9769192-5
GCTGCGTACAGCAGTCAATCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTGTATT
+
@G4HI@I@?D??EGHG@"HB?CCDDAEGICCEIH?H?GDFGFC@I@BDBECICBDA@DG?@?H@I?HDDHCBBDBB@CF?ABHAGBDGDABEHB@AEACB
@>chr21:9769008-9769192-0
TCAGACGGTAATCTGCCCTTGAAAAGTATATAAAACTCAATGAGGAATTGATCACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGC
+
ACBFAGDFAAI@ABAABGIAH?DCH??DDIGDIDBA@DICHEFDCICC?ICH*IIBC@DHIEEAEDFC@IEGGGBADDCC@CDBAF?B?B??CGFGG@AE
@>chr21:9769008-9769192-1
TCAGACGGTAATCTGACCTTGAAAAGTATATAAAACTCAATGAGGAATTGATAACAAGAACAGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGC
+
ABHBCAC@G?@@G@G+EACGHBAAFFF??CF?BDGHBHAFDBDBFHAIIGAFAFIAGFG?FICAIDCCFACABCDEAF@?BD?G?D@CAC?IEGG?IBHE
@>chr21:9769008-9769192-2
TCAGACGGTAATCTGCCCTTGACAAGTATATAAAACTCAATGAGGAATTGATAACAAGNACAGCATTCCGGTATCAACAAGAGCTTAATGATCTCAAAGC
+
E?C?EBBHEGG?HGBB@FGB?I6AA?I?ABEFGHB@G@IGADHDIE?AG?BCFBHD?G4EGHCHFIAHEHAIBDAFAEGEABI?DGHEHGAEI?C@ICDC
@>chr21:9769008-9769192-3
CAAGACGGTAATCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACAGATCGGAATTGAGCCTTG
+
3/DGEBEIIFAGCCDCAHD?EFI?IC?FBHBI@CIAHBG?CCABFC@DCGB@FD@AECDBDHGADGGBD?FHFFAI?AF@@?@GDCIIFACHEGDACIIG
@>chr21:9769008-9769192-4
TCAGACGGTAATCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCCTTCAACCGATCGGAATTGAGCCTTG
+
?FE@BBAAGCABHABF@@CIBH@BG?E?@HCIFBFCFCEEC?GCC@IABFAEG@?BF@D@@FCBB@ABH?GCEFHCEDFCI%FDFAEEACB@HBF?BGHB
@>chr21:9769008-9769192-5
TCAGACGGTAATCAGCAGTCAGTCTAGACTGATGATTCAATTTCAGCTTCCAGTCTTTTGTTGCTTTCTTCTTCNTTCAACAGATCGGAATTGAGCCTTG
+
H?GI@?EHIID?@AHF@EIB@BD?FD?CA?CHDDEGCFDFC?A@@@@GDDIBDA@EF?D@HC?HICHDIGACHI2FEDECHH?GHEICEEA?EBIHDB?C
@>chr21:9773160-9773219-0
ACCACTATGTCAGCAGAACTGTGTTTCTGGACTGCTAGCAGTTTGTCAGCTGAACTGTTCTGGGTGCAGAGATCGGAGGAGCGAAAAAAAAAAAAAAAAA
+
HCEFDDE@FDABII@D@@?@C?GCDGACFD@ADFAIC-?FI@@B?GF@@IBDGHCFAEBBGAIDC@G?FD?CGIIBF4IH@IDIDA@?ACD(EAFE?EGC
@>chr21:9773160-9773219-1
ACCACTATGTCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACAGTTCTGGGTGCAGAGATCGGAAGAGCGAATAAAAAAGAAAAAAA
+
?DCFCB?IHEEC??FCGFDDI@ACHIIFFEHGF@HF@?FB?IADIG@BAAA@DHB?B@E@EAI@BFBCE@DDG@GA@DHH@D@EA0?HIBBF(CECFHIG
@>chr21:9773160-9773219-2
ACCACTATGTCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACAGTTCTGGGTGCAGAGATCGGCAGAGCGAAAAAAAAAAAAAAAAA
+
BDGCDGAECGAFECDBEC?GHC@4BDGG?EHG?BA@BG?ECAGGFAIFC?FDGGGHHEFEGCECE?DF?FFFG@GC9HBB?@?CBCD?G@FB@HFBEEDA
@>chr21:9773160-9773219-3
ACCACTATGTCTGCACCCAGAACTGTTCAGCTGACCAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
GCGCHHFDC@EEBC??A??CFB?CI@BAH@HG?GI<ABIG@ICCCEC@EE?FG@II?FA@EBBB@HDAECC@FB?HH?D@FDFH?FCAGGAGHHI?@AID
@>chr21:9773160-9773219-4
ACCACTATGTCTGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
EB?G?HIE?CHAGABFGAEGIHEDHAGAEAG?ICCAAGAE@E?HCCFE@EHH@DA?C@BAF@HH?FHDDFIFBHGGH@G?BGE@BEHACADAAI?ADCH@
@>chr21:9773160-9773219-5
ACCACTATGTCTGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGTTAAAAAAAAATAAAAAAA
+
A?CE?@ICBEAEGACBAH?D?DDI@C?A@H@CIBCGBFACBABEG?ABA??@?G?HEB?CCHBFIDFAIEF@@?DGC?@?E&#HGEEHBG?C6HBBDAAD
@>chr21:9773160-9773219-0
CTCATACCACGCAGCAGAACTGNGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACTGTTCTGGGTGCAGAGAACGGAAGAGCGAAAAAAAAAAAAAAAA
+
BEHDFEBDGBGG@?F@GFBIIE-DCFBCIIB?AI@IG@DAF@ACE@@BE?DD@@HCH?CA?A?A?@DGIBH@?-GII@BIAHIGFEAIEG?I?@@IHCIE
@>chr21:9773160-9773219-1
CTCATACCACGCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACTGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
DGFF@FFCAF@DIIC?ECHAGDC@)CDCG??BHIEBF@IFACHAHG?EIAIEBA@IAID@?D@DBGFAII?ACAADHFFBIIC@IBFCDF@?FCGEFA?A
@>chr21:9773160-9773219-2
CTCATACCACGCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACTGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
FIA?IBH@BFE?DHAFDFCIGCAII@@C@AGE?HACBHEHDICIG@IDDHG@?AIFBIDIBIID?@CDDDCCBCAIHHE@F?D?CGAFH?EH@FHII@BE
@>chr21:9773160-9773219-3
CTCATACCACGCTGCACCCAGAACAGTTAAGCTGACAAACTGGTAGCAGTCCAGAGTCACAGTTCTGCTGAGATCGGAAGAGCAAAAAAAAAAAAAAAAA
+
ABEGAAD?GGFABIIFHI?G?AEIBDE?;GIHBA@DG@B@BGDIAIIEAHBH?EA3#EGBCB?GC?DFABH@AFBIFGCIHCA5E?IEDHCEAEE??HIE
@>chr21:9773160-9773219-4
CTCATACCACGCTGCACCCAGAACAGTTCAGGTGACAAACTGGTAGCAGTCCACAAACACAGTTCTGCTGAGATCGGAAGAGCAAAAAAAAAAAAAAAAA
+
I@A@DHDFIBECA@FHIFEECDGI?HBBDGD7CADFH?EHABGFD?DFH?HCD'HBHDDBGF?GI@BHIEA?CB??C?AGEIF$DDHCABID?FBHBGHG
@>chr21:9773160-9773219-5
CTCATACCACGCGGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTCCTGAGATCGGAAGANCGAAAAAAAAAAAATAAA
+
A@FD@CHGCIIG#ECE?EHEC??CGI??BH@IE@FA@?@CFG??BEC@GD@A?GD@A@B@GEEFIC(GEF@IDHD??AIEI0ACBHCDAH@H5?A@>DAH
@>chr21:9773160-9773219-0
GAAGGTCCTCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACTGTTCTGGGNGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
GDBHGF@I@@?HIEI@AABBCIHADFI=CFIG@HAH?BF?GIDI?GDH?DGCB?GBG?BFI?I6DA@@D?DHFC@GCE@ID@?HAB@EDEI?BIFB@A?C
@>chr21:9773160-9773219-1
GAAGCTCCTCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACAGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
?C?I5E@A?AEHIIIFFFGDD@EBH@@ECH@I?AD@C@?FA@DGG???HBACBEEDEIF?EDH@DEDIFEC?C@@A@EA?BD@B@?@?IDBF@?CE?@HG
@>chr21:9773160-9773219-2
GAAGGTCCTCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACAGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAATAA
+
DEC7DIHHIFFBB@DFHCCBFE@CB@AHIFFACADH?EIGBH@ABDHEDCC?F?BI?@@BAEIHIBEDIFBGHAADI?CIFC@@AHI@DBFBD?E?F.FI
@>chr21:9773160-9773219-3
GAAGGTCCTCTGCACCCAGAACTGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGATGAGATCGGAAGAGCGNAAAAAAAAAAAAAAAAA
+
F@GDEBG?CID?DE@F?HI?BBAHF@H@@IHAEDFCIDGDIGADCBDCEG@IBIG??IDDGBHHE)EIAIDECD?EAB@HBE$F?IGAHAB@ECEC;BBG
@>chr21:9773160-9773219-4
GCAGGTCCTCTGCACCCAGAACAGTTAAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
F.FC@CG@CFHG@EBFEHDAIFBBF?3?FCFEEB@CFBCIAC;EFCDFIG?DEBGIHAHB?GEDFFCCAEAE@EC@EIDHAFHH?CCAIFBEHE@BGHDF
@>chr21:9773160-9773219-5
GAAGGTCCTCTGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
?FG??@?CEBGBDGCEC?@DG@C@?GD@B@CFDHGAD?A?IIG?DHFICECHIHDFACEIIEDDCDDFD@HGFGEBEII@FADCCEFBAB?FHFCHEBEI
@>chr21:9773160-9773219-0
GCGGCGTACAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACTGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
DCAIHGEAIEBBE@CIGA?EG?GE??FEDDCBEAGHC@?BGGIII?GDD?FEIIEIIC@HBBFBC@A?EGA?CFDI@?GCCFD?HCBBD@EDBGCFEBD?
@>chr21:9773160-9773219-1
GCGGCGTACAGCAGAACTNTGTTTCTGGANTGCTACCAGTTTGTCAGCTGAACAGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
@I@BDH@FDHDHIHDEHA-EHCH?DI?ID*EIF@BHDDCIGG@?@CIHAEIDFHDEGAHBDDEEBCBCDIHG?BAA?EHDG?GEE?G?BFH@EIEAGEFF
@>chr21:9773160-9773219-2
GCGGCGTACAGCAGAACTGTGTTTCTGGAGTGCTACCAGTTTGTCAGCTGAACAGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
DAEGIIGAFA?EEDDC@IDI@CHIECCBB5DCGFBCHCBDBCFBDFDDHDCHGBA?CBHGEAEC?EBBABEDHGBF?GBIGFGEHGHA?CHICECGG?@E
@>chr21:9773160-9773219-3
GCGGCGTACTGCACCCAGAATTGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACTGTTCTGCTGAGATCGGAAGAGCGAAANAAAAAAAAAAAAAAA
+
B?GECHHDECFB@AFH@FEE=B?E?ABCGA?IDEB@ACH?@IGHH@IGABCG@FEIE:HDD@ICCC@BEIABA@D@EDIIFECC,AIBF@@IIBHFBFFD
@>chr21:9773160-9773219-4
GCGGCGTACTGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
D@FDB@AGAEGB??AAHF@?IGFHGHDDHGICGD@GI@EG?@EGD@DFIC?GHFFE@D?DCCCC@H@C?EFDFFDBBGB@BACCCE?DHDAIG?A@DC?G
@>chr21:9773160-9773219-5
GCGGCGTACTGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGANACACAGTTCTGCTGAGATCGGANGAGCGAAAAAAAAAAAAAAAAAAA
+
DGGEDFG@FAHECIBGDECAFGBD?DGAE?DBC@AF@CDD?@BFFHCHG@??/DGDGCGDIFBGE@@CGEBDI@C(GD?@FGCGE??CCEDC?CEAIIGF
@>chr21:9773160-9773219-0
TCAGACGGTAATCAGCAGAACTNTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACTGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
HD?GGA?BEI?CFGFCHC?IIB7AI@GDGAECBIBG@FF@CDABGACHFGIDEH@G?FGA?C@BD?GD@?FCEAEEB?B@D?GHFFG?B@DA@ABC?FBD
@>chr21:9773160-9773219-1
TCAGACGGTAATCAGCAGAACTGTGTTTCTGTACTGCTACCAGTTTGTCAGCTGAACAGTTCTGGGTGCAGAGATCGGAAGAGCGAAAAAANAAAAAAAA
+
A@?BGGHBHDGIGHCEH@CGAI@IFC@EACD5I?F@AAF@E?I9GFAF?IDECFG?FGFBCDFA@DDCF@DEDGH@FCCEAEAIDA?G@I@7ABHI?FFC
@>chr21:9773160-9773219-2
TCAGACGGTAATCAGCAGAACTGTGTTTCTGGACTGCTACCAGTTTGTCAGCTGAACAGTTCTGCGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
DFIE?CD@GC@A@AGBDCHHIE?BAIAC?H?EEEB?GHB@@HA?AIFCGFH??BH@H?G@HFCC+F?I?D?ADBA@BIHHIHEFBGBCABGIDEDAH@ED
@>chr21:9773160-9773219-3
TCAGACGGTAATCTGCACCCAGAACTGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
C?HBFFGGFAE?C?IABH@@?H@I@H@HIDDI?E?DAIB@IFIBA?GF?BGIEHE?B@?CDDICAIBC?GBGB?@DCCFD@GEH@B??CFHIHGF@C@HC
@>chr21:9773160-9773219-4
TCAGACGGTAATCTGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCCGAGANCGGAAGAGCGAAAAAAAAAAAGAAA
+
?I@?IGAHF@CBHDIDDIAIDEDI?I@?FICCEI@FIA?HAE?H@FAHCF@G?DEIHE@DBBE@F@@CF"H?AD+FEBBEIHHGHD@IE@CFEECD;H?D
@>chr21:9773160-9773219-5
GCAGACCGTAATCTGCACCCAGAACAGTTCAGCTGACAAACTGGTAGCAGTCCAGAAACACAGTTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
&ADADD;H2@C?EH@?HBG@BGECACD@HACIGGEDIDBDIFAFBAAFHGCI??IAGB@EAI@?BFD@F@HFHEDBE@AII?CCF@DEIHI?HD?HC?CG
@>chr21:9773216-9773284-0
ACCACTATGTCAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAAA
+
EEHDHBHEEACEHF?I@@BGDHGI?IECHEEG@C?CHF@DFGDGGIFBDFEEC??GAHAG@B@DDDGIEBCBI@AFAFADBCIGEACFFH@EAHEBFFCE
@>chr21:9773216-9773284-1
ACCACTATGTCAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGGGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAAA
+
DAFCG?BIGG??BAFCIBAFAEIG@D?EHF@BAGFFEDHIFAEIAHAHABEACHECECEIHBI+@?IAI@EDBB?GDE@DACCG@C?AH@@GE@@HCHDE
@>chr21:9773216-9773284-2
ACCACTATGTCAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAAA
+
EDFIICDFCBCA?DI?GIECIGFF?CF@GDEIBHG?DFHFCCEBED@?CAIBEEEFGBFBBAHABEFGCI?AEDHD?BHCD@?DFII@IFA?IE?HFEBF
@>chr21:9773216-9773284-3
ACCACTATGTCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGATCGGAATAGCGAAAAAAAA
+
?@AFEDGCC@CEA?@??EIHEI@@EHDEIBF?GADG?CBFE@?CD@@?GDEHBA@BE@CEEGC?D@HA?HGFBADC@IEEB?HEDH@,DECC@HBDEGFF
@>chr21:9773216-9773284-4
ACCACTATGTCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGCGATCGGAAGAGCGAAAAAAAA
+
HC@D?@BIEBDHHDAG?EACDAIFF@IHF?CAIFBFCB@CIAIAGGEH?ECA@?AFBCC@@HIF??FBECGIA?FHAE0B@G?DEEBBAF?GEDIFFEA@
@>chr21:9773216-9773284-5
ACCACTATGTCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGATCGGAAGAGCGAAAAAAAA
+
DBGH@CGBEAAH@?HF@ABBH@IIEF@FGAB?FH??FHE?DEACGGA@HGCFCHGBDBFIIGCA@H?CIBE?FC@GHBGECBDIBICGB@HFBBIBG?BG
@>chr21:9773216-9773284-0
CTCATACCACGCAGCTTGTCCGATGACGGAAAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAA
+
BCDEIIGGIEAD?BBABDICDE?BFAIIBIIEGG?CGIFBCHBGCD?CCFDAIHBG@9EHBID?A?B@DGAFCFH@@CCB?ICGH??G@@BIIBC@GB??
@>chr21:9773216-9773284-1
CTCATACCGCGCAGCATGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAA
+
CIFCBEFB8CAEH@I8DIDDEHCFCGB@CCBH?CGGG@G?FB?AB?@BIHGF?AICA?HFDB@G@GF@DGIHHGD@CFG?CBIDIA@@IC@E?HD?HBEB
@>chr21:9773216-9773284-2
CTCATACNACGCAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTGGTGAAGGCAGCGATCGGAAGAGCGAAAAAAA
+
GCA@AF?-?GFFHDB??GB@GEDGBA@BEFCCIAE@?CACFDGCABACIHCE?@BHDHCEAHGA@CB?4IBC@?FHGDB4??ABADD@B?@AIGDAI@A@
@>chr21:9773216-9773284-3
CTCATACCACGCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGATCGGAAGACCGAAAAAAA
+
DCHBH@EGDCIIHBHIII@FEB?DHBHED@GG@FICC?EDHGGF??@EBA+FHDCDCGC@ACIGIDIAGHH@1A?IBA?HIG?C@CID@H;DEDBEA?EE
@>chr21:9773216-9773284-4
CTCATACCACGCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTTTNCGTCATCGGACAAGCTGAGATGGGAAGAGCGAATAAAA
+
DEIFFAC?AI@AEHGFFEC@GHBF@IEFEI??EEE?GBICFI?@DCIEBFCGI?FG@ACFC6IDGCCD?HGECEA@FIGGA@D<FC@BHI?HE?I*AHDE
@>chr21:9773216-9773284-5
CTCATACCGCGCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTTTCCGTCATCGGACAAGCTGAGATCGGAAGAGCGAAAAAAA
+
?IGADEHI"GGGG@IEBFGCB@DHFHFIE?@@EBIACBHIIGGEF@FADEA?BDID@FHHAADCE@DDEDAB?DEHACIDGEGBAB?FCBFBEBIABF@@
@>chr21:9773216-9773284-0
GAAGGTCCTCAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAAAA
+
BHIDB@IFF@EIFIADGICBCAB@EGFHEGAEEH@FEEFE?IEDCECBHAFDFBEIDA?DFDAGEFEFD?GF?IEIBE?A?CDE@BGHBHD@I?BCH?HE
@>chr21:9773216-9773284-1
GAAGGTCCTCAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGACATCGGAAGAGCGAAAAAAAAA
+
EGC?HBCBGHBAH@CCHGFGA?E?HAAECAHDF?EFEGDEIGE??CABE@?F?DACEFACHD@FAEH?HDB@DFD?BH/FBB@EHDBBE@AICFA@BG@I
@>chr21:9773216-9773284-2
GAAGGTCCTCAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGACTGCACAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAAAA
+
FEDHIC@FFB?CEFBIADGDG@B?IA@IEHI?C?I@HHC?I@FHD?HAG2@DD0FHDFHEDEEGFF@F?G@IIGFFCB@@IIFFHH?DEDAIBGCCBC?I
@>chr21:9773216-9773284-3
GAAGGTCCTCTGCCTTCACAAGCACTCTGCTNAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGGTGAGATCGGAAGAGCGAAAAAAAAA
+
?FIABH@D@CC@?ADC@AFAG@HCFGCHGEF/BFDCCFI?ED@BAF@DIHH@?GEC@BDBABIHEC@@GIBGHA#?ACF?BDADI@EIFBFECEACHCBF
@>chr21:9773216-9773284-4
GAAGGTCATCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
FG?@CHB<IIAFBGH@AGEA@D?@DGAB?EAFCHGABBEDDFHAH@AC?G?ECBFHGIBFD@CGHABDHFCBF@ECGEFHHDC?IABDHDH@IGHAGCDH
@>chr21:9773216-9773284-5
GAAGGTCCTCTGCCTTCAGAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGATCGGAAGAGCGAAAAAAAAA
+
H?IG?HBB@@EIIGIEHF+?DBA??IDEEEG?C?ABADDB@?ABIHC??B@DEI@DB@ECCBFH@@?DI@DAFBCBG@FDBIHII?@@FGCDDCFACICB
@>chr21:9773216-9773284-0
GCGGCGTACAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAANNA
+
H@@?IGAHH?@CHGFDDEEDHDIB@CGHE?H?EECCF@HGEHFEAFHIBBHDIHEH?F?GBD?HGEED@DEHCEAGAAE?FBEGEEA@IHFHGGBIB0;F
@>chr21:9773216-9773284-1
GCGGCGTACAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGACGAGCGAAAAAAAAAA
+
A@HIFBA?EHBEFHAGI@ABEBFAIIBCFBBIBC3DBBAAHFHEEHAEIECBAGA?GDDHCBBHBC@D@IFGBIAIBCCGBE@@:A@@BADIB@AHDICB
@>chr21:9773216-9773284-2
GCGGCGTACAGCTTGTCCGATGACGGATAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
C5EBGGBDGHBHCHBCBG@I?FBG@GEAHI?F?BFFIGIFEIE@?CA@??@HGEFCAIICEEABIFAGBFEHFIHEC@AC@AG?EEADIGFFE@EFIIAI
@>chr21:9773216-9773284-3
GCGGCGTACTGCCTTCACAAGCACTCTGCTGAGCACTCATATTCAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGACCGGAAGAGCGAAAAAAAAAA
+
E?HFAEFHAEGBFDIAADBBBBHGB@FDECCADCFHBFDCABB!?FAIEHID@ABC@FCFF@EBDGDBGIA?FFBHFDE6<DIEBC@C@II@HACGH?IA
@>chr21:9773216-9773284-4
GCGGCGTACTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
EADCGBIFBG??@??AIHGCBAACD@CDC?GH@A?IGCIBE@@BCBAFBEFID@IC?FCE@???H@@H??AHDDGA@?@@D@GCI@HBGFI@?FA@?@AB
@>chr21:9773216-9773284-5
GCGGCGTACTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTATCCGTCATCGGACAAGCTGAGATCGAAAGAGCGAAAAAAAAAA
+
DCFA@GGB?BID@GHFCCGIE?AIFEHICDCFC@BHDBDCADGADHGBHDGDHF?DGGHA@IIHIGBIIFAB?CH?D?AGBI4CCIBFDBEHBAHAEAEA
@>chr21:9773216-9773284-0
TTAGACGGTTATCAGCTTGTCCGATGACGGAAAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAA
+
D"BFHEIAG3AGIHBFDDBCI?CECFID?DFF?FEGHGAFGIABEGHF?FEDE@AADEIABAHCH@GDA?DFDIC@GDECEI@CCHIFEDC@?DCE@GIH
@>chr21:9773216-9773284-1
TCAGACGGTAATCAGCTTGTCTGATGACGGAAAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGTGAAGGCAGAGATCGGAAGAGCGAAAAAA
+
DFCCBEBF?IFH@?CCGHI@C;HEEAAFII<HHDBBHFD??EACIHEHCIDB@DCHCDD?HIHFD??HBDAICE?DF?@@CAD@CGF@C?HGE@DIBGDG
@>chr21:9773216-9773284-2
TCAGACGGTACTCAGCTTGTCCGATGACGGAAAGCACAGCCCCTCAATATGAGTGCTCAGCAGAGTGCTTGCGAAGGCAGAGATCGGAAAAGCGAAAAAA
+
@?IGIHF?IC(CE@ABBFIEACHEG?F?DBDFDAAD@@?G@H???BEEFHDHF??DEECIHAAEDBH??BA9???EDG@DE@DBCD?GA*FD?EGADAGB
@>chr21:9773216-9773284-3
TCAGACGGNAATCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTTTCCGTCATCGGACAAGCTGAGATCGGAAGAGCGAAAAAA
+
@HAFAHCB!IIFG@@@CHCAIABADHB?IF@BHDFE?IBF@?HACI?@GBBECBIIEAAHBHA@?B@ADCIGFF?IH?FFEDGC?@D@@HHDF?@DD@GC
@>chr21:9773216-9773284-4
TCAGACGGTAATCTGCCTTCACAAGCACTCTGCTGAGCACTCATATTGAGGGGCTGTGCTTTCCGTCATCGGACAAGCTGAGATCGGAAGAGCGAAAAAA
+
@I?DAAGGE@BAABECHDFHA?AB?EDGEHIACBGDHHHFBCA@C?H+GA@BGCGG@DIHGF?@IFGD@BBFFCDB?GAFFH?I?HHFCFDIHDII@C?D
@>chr21:9773216-9773284-5
TCAGACGGTAATCTGCCTTCACAAGCACTCTGCTGAGCACTGATATTGAGGGGCTGNGCTTTCCGTCATCGGACAANCTGAGATCGGAAGAGCGAAAAAA
+
ACBAAHCIAHGCAII??DGIC@FHHG?GAD@?FD?I@I?CF/?HFHAH@GIHI@HG>IG?DGG?B?HBEDAHHCBH>I@FC?CCDEFI@DGB@@G@GGEI
@>chr21:9773931-9774081-0
ACCACTATGTCTGCACTCCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGCAGTGAGTTAGACATCAGT
+
DBD@AFICGG@B?FIDGEEIAG@D?CGFDDA@?GA@HEHI@@HFAAFEABFC@?IFEHD@BABFAH?FABD?FBE@BE?CD2?FACC?E@EFCI@?EAHD
@>chr21:9773931-9774081-1
ACCACTATGTCTGCACACCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCAGT
+
EDHCBFG@@DIHHBGB8?EEADBCFCGFAD@GIIIBB@HCGGGEG@EBGF@IHHGIIGECDFAI?H@ABEEBBF@H(FBIHAFIFHA@BCIFG@?ICFAG
@>chr21:9773931-9774081-2
ACCACTATGTCTGCACTCCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTGTGTATAGATTCCCATAGAAGTGAGTTAGACATCAGT
+
IA@G?GCDGCDBCHCACEEBFHCCEFIDDGDIDDBBB@HDDAIGIBBEAEAIBBFHHDDBCIB5D@BGH@AAFDDI@BFA@E?AEHE?B?GEFIGIID?F
@>chr21:9773931-9774081-3
ACCACTATGTCTGCCACTGATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATAATTCTATGACTGATGTCTAACTCACTTCTATGGGAGTC
+
ACFBCG@CEEFIICB#BF1FHGI@FBA?AEEAE@BGDI@DFA@@BDEEDHCDDCIEEDEBCDECCAGAIA@AFI?GIH?E@FGBGCGCII?IAIAGD;DH
@>chr21:9773931-9774081-4
ACCACTATGTCTGCTCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATAATTCTATGACTGATATCTAACTCACTTCTATGGGAATC
+
CDDH@GEIDADBDE6F@DGIEHIAEFFDIFEE?HCHHD@BCBCBF@HEEFABGDCGCFFG@DB@BG?@???IEHC@2D@H?@CEIADA?GFBCHB?DGD@
@>chr21:9773931-9774081-5
ACCACTATGTCTGCCCCTTATTATATNTTTTACTCCCANGGTAGACATCAAAGTGGCTAATAATTCTATGACTGATGTCTAACTCACTTCTATGGTAATC
+
EICADFHFAFDHCHA?FDGEBCHGAC"FAG@D@GGCIC/C?HEI@@CAG!IHGCFHGGI@?EFA@AAE@FEHIHEDABADGGFH@BAHGIIBHGI&D?D@
@>chr21:9773931-9774081-0
CTCATTCCACGCTGCATTCCAGGCTGGGNAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATCGATTCCCATAGAAGTGAGTTAGACATCAG
+
FFDFD2HCCACBG?FA1IFECBIFEBB@)B?HCE?BGIAFEIIBEDGHBE?FIFDG@@ACEEAFHECIHC:DEDCCHBCFBE@FB?GAAIEDGBHDICFD
@>chr21:9773931-9774081-1
CTCATACCACGCTGCACTCCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCAG
+
IIGEFBDFHGBE??DC?BA?FID?BCD@I?@AEHHE??DBCI?GAFE@?AII@BB?GE?EHHGDCHG?H@FG@CIGEABGA?DBCCFGAIC?HAHIAIED
@>chr21:9773931-9774081-2
CTCATACCACGCTGCACTCCAGGCTGGGTANCAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCAG
+
GFAI@F@@DBC@EGCGEEHGGBBHED@GEH2AGAEEBBFCCIEDH@BEGBF@GI@CFCB@?FBCHACADAH?GICFBACDICCCHDAIC?@BCH?@DDCG
@>chr21:9773931-9774081-3
CTCATACCACGCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATAATTCTATGACTGATGTCTAACTCACTTCTATGGGAAT
+
?@@?EAIBDIFGBIB?DGBCDECEGIAE@IDAAI?B@GAAAA?@GF?H@FFH@FDCFHBI?AD?B@GFEDIDCHG@CHCBIHIC??AECIDHGEAHFGHI
@>chr21:9773931-9774081-4
CTCATACCACGCTGCCCCTTATTATATGTTTTACTCCCAAGGTCGACATCTAAGTGGCTAATAATTCTATGACTNATGTCTAACTCACTTCTATGGGAAT
+
C?GCACBDBEEFIEA?@?IHGCGGGIGDGA2HFHGCDDHAF?E.CFCGBB.EDGAGDBG?DABAFF?BHGIAGA!F@CBAA@DIIG@?CBGGGFFD@HBE
@>chr21:9773931-9774081-5
CTCATACCACGCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATAATTCTATGACTGATGTCTCACTCACTTCTATGGGAAT
+
CDG@FHG?FCFAEFG*AAEC6CEDE?EBIGII?GFC@AD?GI?E@FA@?AHIAIF?@H?CFIEFFGFDHHGDFDHE?HD@@+BHGDAHGCAHE?HH?ADD
@>chr21:9773931-9774081-0
GAAGGTCCTCTGCACTCAAGGCTGGGTAGCAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCANAGAAGTGAGTTAGACATCAGTC
+
IEDAFDBIHF@GH@HCG7H@ECIDFA@H4AH@C?IBABBFGDEFCGIFAHHGGFBADICFFGFIIDAAFBEABEDA?*BI@??GGIHDGBFDC?FDFFIE
@>chr21:9773931-9774081-1
GACGGTCCTCTGCACTCCAGGCTGGGTAACAGAGGGCGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGTAGTGAGTTAGACATCAGTC
+
C@#FIDGGGE@@BDACD?BCCFDFDECA?DGDD?G?&A?CF?C@@GI@HCIIGFEEFD@BBFADECBAB@D?BAFFFI??27FGH?CBFE@C@@IA?EIC
@>chr21:9773931-9774081-2
GGAGGTCCTCTGCACTCCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCAGTC
+
F/HEH@CBDED?H?DHBIE?EH??FAEDBDCAAHIFIGA?@GB@D@FHCFIFFIIDBBIC@IIBCFA@?DGH?FFIDA@FD@EI?BCACGCCGCAHIF@B
@>chr21:9773931-9774081-3
GAAGGTCCTCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATAATTCTAAGACTGATGTCTAACTCACTTCTATGGGAATGT
+
EBCH?B?DA@HBI?CF@?@AAC?F?BHACHD@EIAFCHBGEICABHHEDCIIEFCF?CEIICGCCCI8EA@FCGD?FA?FFE@FG?BGHABD?@BGAH,E
@>chr21:9773931-9774081-4
GAAGGTCCTCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCNAAGTGGCTAATTATTCTATGACTGATGTCTAACTCACTTCTATGGGAATCT
+
GG?DI?CI?BD@EDDEAEF?EE?@C?HDB@HFEHG?CAADHIFCCFHI,DGG@A@FGEG?@CHGBDBG?A@EBBABHEA?DCAAA@HGF@EAC?BDAGGH
@>chr21:9773931-9774081-5
GAAGGTCCTCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATTATTCTATGACTGATGTCTAACTCACTTCTATGGGAATCG
+
@CECHEHAC?FBGBE?ABD?EA@GABHICHGI??DH@@3IEDHBHDFGG?IGHEF@F@?H?@BDADFCDAHADHE?CGGADEADAHACHII?D@AAFEB(
@>chr21:9773931-9774081-0
GCGGCGTACTGCACTCCAGGCTGGGTAACCGAGGGGGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCAGTCA
+
@&ADHG?@AHACFC?DCEF?EHAG@@HH@8EGCBA7@C?H?AHFHDIBFAH@DDHFCDB?AAEH@CCGFBEBACEFFFIGBGEHGCDCF?GFAABDI?GB
@>chr21:9773931-9774081-1
GCGGCGTACTGCACTCCAGGCTGGGTAACACAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACNTCAGTCA
+
IFEDECGHFBFF?C@E?C@AICA@HECD?D+FHGCI@HEB@@AGCD@BI?D?DEE@FBGCGCDECID@CA@D@HEDFA?HE@3DEBDEIIB?$H?BCFH?
@>chr21:9773931-9774081-2
GTGGCGTACTGCACTCCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCAGTCA
+
D7CIBFCBGFA@IE?E?BF@IID@HI@GCAAADCFIFIFI@EC@IDBFHHDIDI?BAEIBHFC@EFGFCI?FGECEFBA?BAIDIHFF@IEEDIEG?@F@
@>chr21:9773931-9774081-3
GCGGCGNACTGACCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATTATTCTATGACTGATGTCTAACTCACTTCTATGGGAATCTA
+
GHEFID)IBA?"ACG@HEGAGGACC?BIA5GDGDDIDC?B??HADADF?DAHFFG@HHDHB@DFIFFCEAIEB@HIEC@GIII@GAEEFBFFABD?DGAB
@>chr21:9773931-9774081-4
GCGGCGTACTACCCCTTATTATATGTTTTACTCCCAAGGTAGGCATCAAAGTGGCTAATTATTCTATGACTGATGTCTAACTCACTTCTATGGGAATCTA
+
BGBHADCGD@2IDB@FF?CA?A?HAIBAGHCFEIF@IE?IEI#EGEDFG@DBCAFBA@GFEAFCDCHCFABIBA@C@HCFEFBGGBDAA?ABDIFCE?CE
@>chr21:9773931-9774081-5
GCGGCGTACTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATAATTCTATGACTGATGTCTAAATCACTTCTATGGGAATCTA
+
@DCFBFDFECH@EDAD7C@IFAEGB@F@A?CDBHDDGD@@GCGD@ACIAH?B@HDFDIF6EHBG?BF?FA?ICAFBC@IC"?F@BHF?@GFCH@IEBCHC
@>chr21:9773931-9774081-0
TCAGACGGTAATCTGCACTCCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCA
+
CGBIEDGICBBFEFEHBEACIB@CDFFDGD?IEBHIE?GAAABEHGCFBCBA??@@@AHE@@H?EEH@B?CGBHDAEGGFCBHF?GHEGABH@GC$GBB?
@>chr21:9773931-9774081-1
TCAGACGGTAATCTGCACTCCAGGCTGGGTAACAGGGGAAGACTCTGTCTCACAAATAATACGTTTTGTATAGATTCCCATAGAAGTGAGTTAGACATCA
+
BADGCBGBAHEGC@FI@CCCG@B)EEE?BGGCD@B+D@<EABFCHE@HBA?I4E?GCEA5H@FFFEGHAAFF@BEIDFB@CHEGABI?DFBCHFBFEHI?
@>chr21:9773931-9774081-2
TCAGACGGTAATCTGCACTCCAGGCTGGGTAACAGAGGGAGACTCTGTCTCATAAATAAAACGTTTTGTATAGATTCCCATAGAAGTTAGTTAGACATCA
+
IAEBBDCBBFADCIIH?GECH@@B?FBA@?HC@EGBGCCGH@EAB?HHBF?EEHHFHIIHAIGCE@EAFGCHC?EDHIABIEGDAEG#EGBAACIDB@CA
@>chr21:9773931-9774081-3
TCAGACGGTAATCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTACTTATTCTATGACTGATGTCTAACTCACTTCTATGGGAA
+
??HF@GCCHCBDIEBCIE@GBB?B@AEFBAGI?IAIE?DEDHHB?FI@GCAIEBI@HHF?@&C?B??FBE?ABB?EFAAC@DFEGBGBICDIDFFAAADC
@>chr21:9773931-9774081-4
TCAGACGGTAATCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCAAAGTGGCTAATTATTCTATGACTGATGTCTAACTCACTTCTATGGGAA
+
ADEBHHAGACCBDEFBGE@@C@BDCG?@ICGBD@B?IDEGIIABCHEI?H?HCEH@BFGAHI??I??EGIAI?EA@BB@EFAABGBG@EGC?GFFI?ECG
@>chr21:9773931-9774081-5
TCAGACGGTAATCTGCCCCTTATTATATGTTTTACTCCCAAGGTAGACATCTAAGTGGCTAATTATTCTATGACTGATGTCTAACTCACTTCTATGGGAA
+
CFICEB@HCEHDCG?B?E@@I??H?BACB@?CGCF?ADD@D@F@CD?IAG?$IIDCDA@HEEHAAABBA?AD@IHBDHIDBCDGIBC?H?GCEH@?:HC@
@>chr21:9828003-9828160-0
ACCACTATGTCAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTAGATTCCA
+
FDCBFHDAGGIADECDEAHBII@CCDE@CDAEHGDEDGII?@IFHA?HAGADEA??HB?DFGFED?E?AE??DBI@?I??E@BBFC?DICFE@@B??@DB
@>chr21:9828003-9828160-1
ACCACTATGTCAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTAGATTCCA
+
?IB/BHIHCDHF@EECAIE@@BB@F@?AAIEFEGBFH?BF?EFAIGE$@?IEI@EAC@GDBHDBBBDFGA?@HBGA@??BAFCGA@D?HCE@@FBAIB@E
@>chr21:9828003-9828160-2
ACCACTATGTCAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTAAATTCCA
+
ADBECF?G@@@H@DF?ACA@GGBEII@?GI?HEF?F?@GCFEICC?BEHAH?HEE?HHC@ADHG@F?EHDH?DDA?ECGGCFHH@EHDCE?@@8CFGCBF
@>chr21:9828003-9828160-3
ACCACTATGTCAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACAGTCGTGCAGGAATCGGCCCTTTGGAATCTAATGTTATGTCCCGG
+
DG@FHEADECAG?GE@EDGDA?EBIAHGHAEB?CEEBHHDAEACGGDFDADFDCAGEAE,GDAI?GA3HGAHDDCBGCCAGB@DB@FB)DB?@@?CHHBE
@>chr21:9828003-9828160-4
ACCACTATGTCAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGCGGACAGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCCGG
+
HI@AHI$BFF@HC?AHIGFIEGIGGFIGGFCCDIBFICIEC@HA?E?IHC<@F?FBF@AC?@E@GDDIICAGGHBCE???@GG@?FGBGCDDDBHC@FGI
@>chr21:9828003-9828160-5
ACCACTATGTCAGCTAAAACAACGTAGGGCTGTCCATTGTTATTAATGGGAGGACAGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCCGG
+
GE?FBFECCBD@HEA@CEBAHDB?CGIGCAI9IAACAD@IFCEC@B?FCE*@CIB?FIEDEBDEAGC@ICHGHABEG?CHIDHHHA@CCGCACF@F@DEF
@>chr21:9828003-9828160-0
CTCATACCACGCAGCAAATGACCAGAAAAATTATTCCCAACATATGTCTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTACATTAC
+
BB@CE?HA@BDB?FGGAGEABBABFDCD?@?B@BAG?AABBB??FCG(@FFEHEDC@E?FF@BAGF@D?CDIBCFAB@?GIFD?GC@DBD@ECI3EBH5I
@>chr21:9828003-9828160-1
CTTATGCCACGCAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTAGATTCC
+
@@0DA$IFEFBBGADDEDB?@AG@CBCBCFB@@A??D@FBFGFDADBGCGF@BFGBCDCC?CA@B@CIIDCC?DGIIDIAICIB?IEI?EFHIDD@?ADF
@>chr21:9828003-9828160-2
CTCATACCACGCAGCAAATGACCAGAAAAATTATTCTCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCTGGACATGACATTAGATTCC
+
GBFBCCHHA@AHHHFG?@HEFFHA?FIGD@@D?FCI%EACG?BGCFBCDFCAFAH?BFDACIFED@@FF@ECA@EBFFHB1IGDEHI7?EEAIADFGHEC
@>chr21:9828003-9828160-3
CTCATACCACGCAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACCGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCCG
+
GH?D@DIIGIHEFD?@HEFBBBHBEIGCBDFD?AHEFCCAHFA?C?GB?@GC?@D@DFEA@IGIFEGFD?GAHHA?ACHCDHH@FAHH?GBEFDDF?BAC
@>chr21:9828003-9828160-4
CTCATACCACGCAGCTAAAACAACGTAGGGCTTTCCATTGTTACTAATGGGAGGACCGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTNCCG
+
@DDFFFEEIHDHFIAHCIDDA?GCCFEIBHGCCFCDB?E??HH/DBAF@I@AGFG@HB?HHDBFD@CIID?GD@ECIF?@EGBI?IBHG@A@EIDE#@HH
@>chr21:9828003-9828160-5
CTCATACCACGCAGCTAAAACAACATAGGGCTTTCCATTGTTATTAATGGGAGGACCGTCTTGCAGGACTCGGCACTTTGGAATCTAATGTTATGTCCCG
+
DGHBEBGADGGDE@GEBFF@HBAG/I@H@B@DD?FEIIAFFAI@G@?@GIECDA??=CI?B@@@GEHGDFHDA@)HB?F@CCIHCCHF?HA@D?IHDIB@
@>chr21:9828003-9828160-0
GAAGGTCCTCAGCAAATGACCAGAAAAATTATTCCCATCATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTAGATTCCAA
+
DBD@@HGAC?HAEBIEHGDCA@GCB@@FIGE?EDH@A#GBE@GFFAEF?CHGHA@DADCGAGICGHD?F@CE?FFDIIIA?@FF?DDFD@@IE@HE?GFI
@>chr21:9828003-9828160-1
GAAGGTCCTCAGCAAATGACCAGAAAAATTATTCCCAACATATGTGCGTCTTTGAATTCAATGGNGACGCTATCTACTGGGACATAACATTAGATTCCAA
+
CDABIDADBBEDBCHD?E@GIG?HF?ICEGCIG?@I?@CABABDFC;GA?IHABIACIHIGHAA0@BC@HCE?FBAG'FHF?@@DA@C@HFGEA@ABC?A
@>chr21:9828003-9828160-2
GAAGGTCCTCGGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCCATCTACCGGGACATAACATTAGATTCCAA
+
CBI@FAD@@?)E@CEIIH@D@AAHC?@CFCHBBGHHHIE?HHEH@@HCBHIGDEIGAFEE@ABFEIIGBF4IFHCHHIHFAECAH@IEIHABHHIDAGGE
@>chr21:9828003-9828160-3
GAAGGTCCTCAGCTAAAACAAAGTAGGGCTTTCCATTGTTATTAATGGGAGGACTGTCTTGCAGGACTCGGCCCTCTGGAATCTAATGTTATGTCCCGGT
+
BAIIHHE@DFGDIA@CBC?AB-GIADEFG@@FAHBHA?ICEAACEEGA@GF?FD*ECCIG?@F?EBFA?GEAD?G4?FBIBDEADI?HGG?G@GF@BCBC
@>chr21:9828003-9828160-4
GAAGGTCCTCAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACCGTCTTGCAGGACTCGGCCCTTGGGAATCTAATGTTATGTCCCGGT
+
DDH?HBFHACFGFHH?EGHIAG@?CDGADEFACABE?E@CHCHF@FDGBHCH?GEH?DACE@A?EFAFHAH?GAHI0AAGEEFDE@IH@G?EEHDEB?HF
@>chr21:9828003-9828160-5
GAAGGTCCTCAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACCGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCCGGT
+
@C@FHF?BF?FHGB@BF@DDA@ECFE?CCBAEF@BGD?BHDFHHCEDEEFCFHGDB?E?@@C@FCCDHBHH?AHHG?CACA?IFABHEHFHDB??DC??E
@>chr21:9828003-9828160-0
GCGGCGTACAGCAAATGACCAGAAAAATTATTCCCAACATATGTGCGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTAGATTCCAAA
+
GCEABHAI?@@GGB@CIBHE?A@F@AEB?G?GAHHBBCHIAIADF4@IFFFGD?GGCBFFIDCIDBIEHC@@DHFHB?FEGF?IFEB?C@GAEFCBDD?E
@>chr21:9828003-9828160-1
GCGGCGTACAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACNCTATCTACCGGGACATAACATTAGATTCCAAA
+
CE@I@CGAAD@@GIEDHIA@EAIHIIBHFCBDA?FHBA?CEHDEG@@DCEAD?@BAHHDIFDAEEBD4?E?@BEH?DCACAI?GHCACFII?EIDBACCE
@>chr21:9828003-9828160-2
GCGGCGTACAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACATTAGATTCCAAA
+
?E?@GDD?DFB?BHFBHHI?ICAGEDFAGEDGCGFCB@B?I@GGIGFE?EICDEBGA@BFGFBI?GFGGFAC@BC?AAFDIHGEDCHBIGEEBAGCBAGB
@>chr21:9828003-9828160-3
GCGGCGTACAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACAGTCTTGCAGGACTCGGCCCTATGGAATCTAATGTTATGTCCCGGTA
+
?IGCBGBBB@EB?DCBAGG?IDEEEBFB?FGGHAGE?C?CB@EG?GC?DGA@ADD@HFEHFFBBBAEGDHIECC(FABCGA?CGHIHEBEIACIC?FGBC
@>chr21:9828003-9828160-4
GCGGCGTACAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACAGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCCGGTA
+
AHDGDIG?DBIEIEIAC@D?FEB?C@HGHFEAGC?GFAFDFH@?BHD@B?ICAAG?FFAGBCAEC??AB?EHD@CI?FBEH@H?BAIC?HABIH?FABAH
@>chr21:9828003-9828160-5
GCGGCGTACAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACANTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCCGGTA
+
HGFCIE@E@@?@CDH@CBHBB@IH??AGEAHHFFE?BA?ECGC?F@?AAHFCBD<B@BGDHFAGHG@GC@DAA@A?EIDGDFEIHGH@@B??AIEABAIB
@>chr21:9828003-9828160-0
TCAGACGGTAATCAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATNACATTAGATTC
+
HAHHIA?CICAABHAIHD>ECHCIGGGGAGHCAAGEDCBG?A?GGBIE@E@ED@CIFBFIIEBHDDHABG?FGGG@HBB?H?FF?BGG-DG?DAHAAFBC
@>chr21:9828003-9828160-1
TCAGACGGTAATCAGCAAATGACCAGAAAAATTATTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGACATAACTCTAGATTC
+
A@B??C@IGABEFEA?AGEBDHHDIDA@B@ECEAEDGIACEFI@E?B@@BAC?IIEBGC?DCECCACI?DDFDCEEGEG@FIEFHFHBBFI!-BACHEC@
@>chr21:9828003-9828160-2
TCAGACGGTAATCAGCAAATGACCAGAAAAATTCTTCCCAACATATGTGTGTCTTTGAATTCAATGGTGACGCTATCTACCGGGGCATAACATTAGATTC
+
BH@FCGEDCIDHEED@DEIEAGCHGIBICD?ID:CGFAFAAB?DDHAGAFIED@H@D@IBBDBI?EBBEECEEEIFHBCGH?@E!HD?CE?FHCCCCBEF
@>chr21:9828003-9828160-3
TCAGACGGTAATCAGCTAAAACAACTTAGGGCTTTCCATTGTTATTAATGGGAGGACAGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGATATGTTCC
+
?BGAF?DA@@=@G@?CIICDBE?DH%BFBGGCFDEA@FD@I@EEE?ICFEFD?CFAFAHFIGB@?IEFFE@ACGGAAB@@BBACG?@ADGH(@EH.G&DC
@>chr21:9828003-9828160-4
TCAGACGGTAATCAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACAGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCC
+
IF?H?BBAC?CB@AGEGHDEB?I?HHF?BFIHIFBBEIF?DFIEHFAIF@AEIIBBHFEEHH@EDDE?BABFEGEEC@@EEHC?@CFE?HCEBDB@IFFH
@>chr21:9828003-9828160-5
TCAGACGGTAATCAGCTAAAACAACGTAGGGCTTTCCATTGTTATTAATGGGAGGACAGTCTTGCAGGACTCGGCCCTTTGGAATCTAATGTTATGTCCC
+
EGEHIBGHH@IGFEIBAEC?GHGBCF@DB@HB?HFGAFC@EE?CEBF@HH?@GHEIBA@C?AFBAHIGHGIH@GFCHCGG@ADCCDF?CHHEFA@@EGDD
@>chr21:9829049-9829115-0
ACCACTATGTCTGCGCGCGATGCTACTTAAACCCACCCTGACGGGCCTGTACTCAGCTCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
?G1ED?DAGGFI?G@ADDICGHE@G#IC?FDGFDFCDDCEHCCIBBA?BFABD@I+BDBEDCHAF?@CB?@?AFHIFIH@EIAIAIHDHBB@?EEI@FH@
@>chr21:9829049-9829115-1
ACCACTATGTCTGCGCGCGATGCTNTTTAAACCCACCCTGACGGGCCTGTACTCAGATCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAACAAA
+
?BCC?CHA?@?GFB.GI??HDF?@=DEEBEEIC@IH@?IHCDDCA?HHAC@CIGIFHFBBHGDDIGIHDB@BBHCCBEF@BA>HHFIG?I@DCHCF=B@G
@>chr21:9829049-9829115-2
ACCACTATGTCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTCAGATCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAACAA
+
@CDGAB?AA@GFGC@G?GF@DIEBDBFGBDI?FCABF@@??IHBC!CGHBC?AGEHABHI@FHB!CDEA?A?FIBEA?FCA@HFBGGE@HD?DGHDH0A@
@>chr21:9829049-9829115-3
ACCACTATGTCTGCTCGGCTCTGTGAAGATCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
@HCDA@?AG?D@?D@DAC@FFBHDG@HB?EA??DCGF?FBAACAGCIFD?F?@BHIEAFBCB#GAE?F@FAFHIF?AHI@?@DDHGFEAAECDCFF?BGC
@>chr21:9829049-9829115-4
ACCACTATGTCTGCTCGGCTCTGTGTAGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
G?HEDC@CEDCGFE?IDF@CCECH@+EBFFHF?ACC@C@EFGGHBEEHBBIDGDAA??CFAIBABHFIBCHAGDIDDGGI@C@G?GCDGDB@BGBAHB?I
@>chr21:9829049-9829115-5
ACCACTCTGTCTGCTCGGCTCTGTGAAGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
GIHCCI(B?DHEBIHEGGEBGCED@BFCG?AADBE@GADCIHEHGIDACE@HH@?C@FEI@IIIHHGAECCA?CFAIIAHD@FBH?D?IDCFFHEAFDBC
@>chr21:9829049-9829115-0
CTCATACCACGCTGCGCGTGATGGNATTTAAACCCACCCTGACGGGCCTGTACTCAGCTCTTCACAGAGCCGAGCAGAGATCGGAACAGCGAAAAAAAAA
+
D@GGBAAABB@G@D@CGE!BE@H4%BCHGIG@HFBG@GI?I?@?AHA?BIHH@BAICGE?FEIGFGIG@@H?@?GECF@@HEICIG/BE?BEIHAGA?G?
@>chr21:9829049-9829115-1
CTCAAACCACGCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTGAGATCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
F?AC:C??HHEEDFCGFC?GGBGGFI?F?EBFHBIEFAI?HDHHI@@@G?I?HC/GDDADACEDH?EABG?F@F#GDGFEGDBIDFFHDI<?AI@C@CBG
@>chr21:9829049-9829115-2
CTCATACCACGCTGCGCGCGATNCTATTTAAACCCACCCTGACGGGCCTGTACTCAGATCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAAAA
+
?DHA?F?EC@?EIBECDGAEIG9C@HHCFFFA@C@I@IE?CDDHGEE?IGHGIE@@ACC?A?BHGHHBHEAE?HFG?EI@GAADHGIA@EECIEHIIGBC
@>chr21:9829049-9829115-3
CTCATACCACGCTGCCCGGCTCTGTGAAGATCTGAGTACAGGCCCGTCAGGGTGGGCTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAA
+
I?EAAEBG?HAD@C@!ACAEG?@DB?EGDD@IAG?@CG@H@??HGCF?DHEBECIB/G@GFBGFDD/@FGDE??@FBDBGEBE@@CIAFGEBG@EHAGHF
@>chr21:9829049-9829115-4
CTCATACCACGCTGCTCGGCTCTGTGAAGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAA
+
IGA@EF?CBHGFDGBIFGC?GBDI?@EAI@GCIH?@HB@IBA?DI?IIHAAHD?CGEBIBGDGBHD?@HCH@FHE@GII@H@DDIIHGE?A?AAHI@EFF
@>chr21:9829049-9829115-5
CTCATACCACGCTGCTCGGCTCTGTGAGGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAA
+
@HCCB@IDDFBC?@FEIH?DDIFABAA+AB?FI@HHAAGBG@H?ID?GG?HD@DD@HAEGGAICG?IGGCDBH@I@GCAHDG@@DBECAGDAB@HF?-@C
@>chr21:9829049-9829115-0
GAAGGTCCTCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTCAGTTCTTCATAGAGCCGAGCAGAGATCGGANGAGCGAAAAAAAAAAA
+
E@I?EIEEIDAGHAFEFAHFAG?HDID?BE@HCDD?CFE@C@G?CCFDI?HAGAB(BFG?C?-?CIGHF?B@EA@@?CFECGD&G@@E?AHB?I=I?DEI
@>chr21:9829049-9829115-1
TACGGTCCTCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTCAGCTCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
$?!EAGB?DCEE@@HBAI?BG?AGAC?BABEH@GCCCCBC?GCCIDIGB@AIGDA@HHC?CCBDFCE@DAH@@BA?HBDCC?IBB?A?DCA@IBBGGAHC
@>chr21:9829049-9829115-2
GAAGGTCCTCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTCAGCTCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
B@DDE?AAEI@HH@CIBC@EFEHHCI?@ABFGDCDGAACBFCGFHCHF?CGDIII@EFGBDBAE?BGGGHDHH?FC??FFCGEGDEEFI?FICHGAFHC?
@>chr21:9829049-9829115-3
GAAGGTCCTCGGCTCGGCTCTGTGAAGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
ACDBFB@DGB$IAE?C?FE@AEAACB?@EAA@I@GAED?@GA?BEGIACII@IDIH@GHFGC@H?DDHG?EDBCCB@GEF?H@A@?AHIE@???AFBDB?
@>chr21:9829049-9829115-4
GAAGGTCCTCTGCTCGGCTCTGTGAAGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
EACGFB@IHHAIABBAIAFDACHBDGGEBF?D?HAABFBAA?EECG?AFIIDICDAC@IGCD@EG??AHFCF???DFBIH@?GIGIFHBH?BB?CFFDG>
@>chr21:9829049-9829115-5
GAAGGTCCTCTACTCGGCTCTGTGAAGAGCTGAGTACAGGCCCGTAAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAACGAAAAAAAAAAA
+
?HH???FB@@H!DHC@GAG?B@CFAGG?@IBBFBGGB@EGIBBHC!D?E?@GCBDGDD?BI@FFDGHFCG@CIC?AAGBEABCCEG-@E?AFH?CHGHFE
@>chr21:9829049-9829115-0
GCGGCGTACTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTTANATCTTCACAGCGCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
AHE@CEEGCBG@IDB?A@AFBFGEBHIFFBDHDG?FF?BGIHC@G?FGFC?5D#GIEHIE??CI)H@??BFIHIAIG?GHCFF?AECDGHD?BG@DG@ED
@>chr21:9829049-9829115-1
GCGGCGTACTGCGCGCGATGCTATTNAAACCCACCCTGNCGGGCCTGTACTCAGATCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAGAA
+
I?BIFF?@HDDGACCFG@@CIEACA2@E@HFIHBGICC*CGBFBBCC@FE?IBCADF@F?DCBI?GIEFA?GIHHCF@FGCGFF??7DGCDAEEHAE2GB
@>chr21:9829049-9829115-2
GCGGCGTACTGCGCGCGATGCTATTTTAACCCACCCTGACGGGCCTGTACTCAGATCTTCACAGANCCGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
GDI?BHHI?EG?ABBAFEBG?BFGIC/?BD?EEIBCADBDDDEEAEI@GICI@DDHC@DFI@?GF!B?BCG?A@C@FA@C?BDBFCDG?HEDGHAH?AHD
@>chr21:9829049-9829115-3
GCGGCGTACTGCTCGGCTCTGTGAAGATCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCNCGCGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
@?I?CAIBCABCBBBAGI?ECAFG?DIFGG@AHIICEIIADE?B?@DH@CAFEBADB??BCDADAE2@IGE??FE@DAFAEBDCEII@@E@DFABGFECC
@>chr21:9829049-9829115-4
GCGGCGTACTGCTCGGCTNTGTGAAGATCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
C?FDH?@GHEGHCDHACC2BIIFBBCGDEEHD@IFE??F?CAG???EFA@BHAFAFFFDEBEAA@BCDH?HIBEBC@FGDHDBDBCAEE@GHHF?A@CBC
@>chr21:9829049-9829115-5
GCGGCGTACTGCTCGGCTCTGTCAAGATCTGAGAACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
AEBEBCEHGIECDH?@BHA@FD$?GHFIFF@?I$FHI@FECFGFDI?EIDHG?CHFGFADEF?@EECBHCA?EEFBDEHDGBD?HB@BGB?G@CC?D?HB
@>chr21:9829049-9829115-0
TCAGACGGTAATCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACNCAGCTCTTCACAGAGCCGAGCAGAGATCGGAAGAGCGAAAAAAAA
+
@EIID@CGGH?DDDCI@GAEDDEDHHGHBCG@@IC@ABECGBDAGFGH?CHCFG+@@ABHDDCAA@?I?DHGEID?@AHE?HBA@EABIBCBEGIB?@F?
@>chr21:9829049-9829115-1
TCAGACGGTAATCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTCGGCTCTTCACAGAGCCGAGCAGAGCTCGCAAGAGCGACAAAAAA
+
IAIEG?HDFDHCH?D?@CIBBAFB?ACCH?BCGH?E@EFEFI?G@BCHF???@FH?=B@F@@@ACEEBAHIAA?ADFI@E)E?G;CHCEDCHD0EG?F?D
@>chr21:9829049-9829115-2
TCAGACGGTAATCTGCGCGCGATGCTATTTAAACCCACCCTGACGGGCCTGTACTCAGCTCTTCACAGAGCCGAGCAGAGGTCGGAAGAGCGAAAAAAAA
+
I@?EB?ABE?HC?I@ICBHBGIHE@IB@DCE@HG@EEAGHEBC@F?FFFGB?CDBIGGABBIICDHBGCGEC@DAEEFDI3GHBH?DBEH?GA?EACBAI
@>chr21:9829049-9829115-3
TCAGACGGTAATCTGCTCGGCTCTGTGAAGAGCTGAGTACAGGCCNGTCAGGGTGGGTTTAAATAGCANCGCGCGCAGAGATCGGACGAGCGAAAAAAAA
+
ECFBGB?DID?@ABEBD??ECH@AFIFAC@?AFCEHEGCCDBEGB;EE?FBAHA@HCICBFADDIF@@=HAH?GHG?EHHAFHDB@#B?IFCHIC?EB@F
@>chr21:9829049-9829115-4
TCAGACGGTAATCTGCTCGGCTCTGTGAAGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAAAAA
+
@GHE?EAHHDEBBBGFC?BBHBC@@A@H@C@IHHEEEFHBFABFDIBIEF?GFC@CGHDBGAEHGI@?HIHGGG?@CDB@EEAHAH@HFHGBDGCIBHC@
@>chr21:9829049-9829115-5
TCAGACGGTAATCTGCTCGGCACTCTGAAGAGCTGAGTACAGGCCCGTCAGGGTGGGTTTAAATAGCATCGCGCGCAGAGATCGGAAGAGCGAAAAACAA
+
AEH??GDFGDGFAFBAFCADI5EE'AA@GBIB?HIAAGEIHFBHI@IHGFAIG@@HDH?IH@?EGECFDGFD?5D@@FD?IBE?GBC?CAHD?GI?E1B?
@>chr21:9831658-9831832-0
ACCACTATGTCAGCTACTGAAGATTCCCTCCTGCATTCCTTCCTGACACACAGGCCAGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGGG
+
D@C@ECEGFGEGEG@?IHDIEC?EADCIGAGEI?H???CEGCDF?@DFDEEFCG@?9FIHIFGHHADBHBHDCBGAGFDAFBIBIAF?FDGI@G@GFIDA
@>chr21:9831658-9831832-1
ACCACTATGTCAGCTACTGAAGATTCCCTCCTGAATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGGT
+
?I@?FAA@C?HIII?IEE??EEIAB?AHIHHA?>?@?DAD?HA@CHDFD@CEAB@BACEB@CGGDCHEGGAEHFC@BAE@AFEIGC?IF@AH?IIDHBA(
@>chr21:9831658-9831832-2
ACCACTATGTCAGCTACTGTAGATTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGATACTCTCACACTCTTGCCAGCAGAAGGGG
+
@?IFAIGICEBDA?BI???9?B?CEA?@ICDGHC@B???CD@IE@GBAAEE@?@IBHEAHFH@DAI@FIC+IB?@DCCECHABG@DHDG@@EEHG?HCEI
@>chr21:9831658-9831832-3
ACCACTATGTCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCCCTT
+
?ICBDCB?@HDH@@EEEGCDIDFIGH?GBABIEFFHBBF=CIFIGGIAG@EF?ABGACBEACBICBAHFGEFEI@AE@BFG?EICAGCFDDEFFAB?E?H
@>chr21:9831658-9831832-4
ACCACTATGTCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCCCTT
+
EFDGE@DBEDIDF?FGIAECFH@IEHHAGDEFBDF?FIIADFDDFHAI@DBAD@A?HEGIGEDHFIH?EEGFC?ECAFC@@CAA?A@ID@ACCDDAIECC
@>chr21:9831658-9831832-5
ACCACTATGTCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCCCTT
+
ADI@FBFBE@BECFAA@EA@BA?AE@CCIHCEGG@GI@BI?ADA?HGHIG@A?A?BHHED@@DIAH@?AEFGIEBGEH@BHDGABIIDGEGDGIAEDE?F
@>chr21:9831658-9831832-0
CTCATACCACGCAGCTACTGAAGATTCCCNCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGG
+
GEB?DCAHCHAC?GBICHICEDEBA@I@C*GHGI?D?AGDDDDD??DE??AEE?BADIC<@CA@@D?GF?D?AGBBHH?HD@GI?HDHCGID@IFEIHIH
@>chr21:9831658-9831832-1
CTCATACCACGGAGCTACTGAAGATTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGG
+
IEFFGADHB@I7GFIAD@EEEBGD@F?IIADCI??IIDHIIDD?DH@A?@FFB?FCHCFFGB?EEF?A?DAD?DDB@IFCCIDGBBEFIAIGGAAABFGI
@>chr21:9831658-9831832-2
CTCATACCACGCAGCTACTGAAGATTCCCTCCTGCATTCCTTCCTGACACACAGGCTTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGCAGGG
+
DACCADIECI?ECDI@?DGE?HEADH?FGBD??CBGGE@GGBFGAIEH?GDFG???/?EFHBIAFCDDBEEBBICFGCEI4EBBHF@ADE??IGD6GIF@
@>chr21:9831658-9831832-3
CTCATACCACGCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTCGGGTGACAATAGCCTTGGTGGTGATATGGGCCATTAGAGGAGCCCCT
+
@CDACGAB?G?EFG@FGE?@ECCFEAEDHB?D?@DHBG?DDECC??BEDCEI:@C@GDF?FH?FGB@@I(EBBGHFIA?C?GA@GEAIFBFG@C?HIDEA
@>chr21:9831658-9831832-4
CTCATACAACGCAGCCACGTCGGCAAGCAGGACGGTCGTGCTACACAGCTGTGGGGTGACAAAAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCCCT
+
CBH@EII*G?GABH@DG@@E@HGAHBCHIEIA%CF@I@CI@H?GGDIHDCHBEEG@C?CHCI0AE?CGH@GE@DE@EA@DCEHHICCD?FIIEFBIBE?G
@>chr21:9831658-9831832-5
CTCATACCACGCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCNCT
+
CH@H?ABIDFIIE?IIHIA@I?CDI@IBHDEHIIC?EFDHGA?FBGE@?BFEAD?CBDGDGCBIHAH@GFIG??IID@?EBDFAHC,@@?FBGA@GC2E@
@>chr21:9831658-9831832-0
GAAGGTCCTCAGCTACTGAAGTTTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGGGC
+
HI?CE?AIEDHG?DCEA@IE?AIFDHIGID@BED?@@ID?@AD@EBHGF@?IAFGGDBACC@AIECEDDBG?C??DAGHBFFCIEBAFICGFCCGBI?EE
@>chr21:9831658-9831832-1
GAAGGTCCTCAGCTACTGAAGATTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCGACTCNCACACTCTTGCCAGCAGAAGGGGC
+
DFEE@DCCDBAHGACEDHACGFABDHECEEF@DCADDDFHBDEIEFEEHE?EIHHI?@HFB@GAI@CE?D>?EDG&C?C?EAH@CFEIEDCHHEEHAFF@
@>chr21:9831658-9831832-2
GAAGGTCCTCAGCTACTGAAGATTCCCTCCNGGATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGNGGC
+
EE@DCIBCBEIC??ACF?CHDC@F@D?@BD-G"CDCC@H?HAFECGH??DABFAF?HI@F?BGIBBFAACICAHH@GD?ICFEIAAIEAADDFIDA%GIF
@>chr21:9831658-9831832-3
GAAGGTCCTCAGCCACGTCGGCACGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCCCTTC
+
GGFDIFGCI?HBA;?EF??CIAG1CEDGAEDG@GCGEFFIHBH@HDBFBABADA@EAGGEDHGC?GD@BFAGGABA@@F?FEAIADAEA@EF?CCAIIDA
@>chr21:9831658-9831832-4
GAAGGTCCTCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGAAGCCCCTTC
+
HAGICCDEDDBHBDCAI@HHHEHHE@AAEIIA?H@DB?CEBBE@DH@BI?DIGFCEEE?EFFA?AE@ADIH@D@@GE@I@@FADCC@IDH<EDI?CBFHB
@>chr21:9831658-9831832-5
GAAGGTCCTCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGTTATAGGCCATTAGAGGAGCCCCTTC
+
H@BH@CBH@CAFIHCBFC@?EBGG?BEHC?I@,ABHAE@EBGBIDC?IF-DGDBD??HHGHBH?BCECGBDGDE'CHD&CI?HIEIEIAG@AIAA@DDHB
@>chr21:9831658-9831832-0
GCGGCGTACAGCTACTGAAGTTTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGGGCT
+
GHHHG?HECIE@DEDAIIBEHGAHB@CAAI?ACBGBFGHC@C?A@CIGBEHFFC@GFDE@DIHI@HHADCFEIHAFIBB@CEI@DIGADGF@HIHE?EDB
@>chr21:9831658-9831832-1
GCGGCGTACAGCTACTGAAGATTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGGGCT
+
?FDIBH@?E@FCI"B?FBID?AG@HCDCFD@?@IHBEED?GBHDDADFE?@FAEI??D@E@IHCEICG@DEECCF@CDDCGBHCHCAC@HFFAIDHEEAG
@>chr21:9831658-9831832-2
GCGGCGTACAGCTACTGAAGATTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGGGGCT
+
GD@AAECDE@FAFDEEDD@@BHHI@FHHEEGG@@IEFAAGIBFC@IIB@DHHB@IH@?F@IDCED@?E?EBBHDIEGBID@@AGIBA?H@@IGF?AAHFF
@>chr21:9831658-9831832-3
GCGGCGTACAGCCACGTCGGCAAGCAGGANGGTCGTGATACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGGTATGGTCCATTAGAGGAGCCCCTTCT
+
FB?GCAE?EGF?I?GF?AHBDADBFDD@G8HDDEIIB%I?CA?IDIEGIDEABGG@CGB@BFHEADEII?BIH1I@?@C*DIGC?ECFF?IDEGA@A?BI
@>chr21:9831658-9831832-4
GCGGCGTTCAGCCACTTCGGCAAGCAGGAAGGTTGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCCCTTCT
+
BHCFABC+DD?ECID0G?@CF?AIIAIFIDA?F;EDFFH@B@@AHFGFGDFA@DE?C@IGB@AHA@@DGD?CI?@H@FBIAIAHIICCFBBAAIEBIF@E
@>chr21:9831658-9831832-5
GCGGCGTACAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGGTATGGGCCATTAGAGGAGCCCCTTCT
+
BGHEAGD?IE?.HAA?@IFGDHCGG?H?@A?G@AFEB@EFI@GB?DI@DHD?BFDEHHD@FCF%DCIBCGBFG4IEIDE@@FCDGFIBCFCHFACCBIEF
@>chr21:9831658-9831832-0
TCAGACGGTAATCAGCTACTGAAGTTTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTCACACACTCTTGCCAGCAGAAGG
+
AIDHAIBBI@BGD??@BG@@DFGBF@CHBA?II@ABBAHF@I@BCH'BAI@DI?HC@?C@EDCHCH?DHFF@@FBDGB/GDABEECAIHIHEG?FH@AHC
@>chr21:9831658-9831832-1
TCAGACTGTAATCAGCTACTGAAGTTTCCCTCCTGCATTCCTTCCTGACTCACAGGCCTGTCCATCTACTTGCTACTCTCACACTCTTGCCAGCAGAAGG
+
CIGHCF/BIBIEDEEADDDHABIEHIE@BHCI?GCA@BFDBAIDD@F@B/IABA@HE?H?AA?EBCFE@FCH?AHEEH@?IEBHG?ECDHGCCFH@DGBH
@>chr21:9831658-9831832-2
TCAGACGGTAATCAGCTACTGAAGTTTCCCTCCTGCATTCCTTCCTGACACACAGGCCTGTCCATCTACTTGCTACTATCACACTCTTGCCAGCAGAAGG
+
IAIBACGBABCIBF@EG?E?3ABADAGBI@FFHGGGHCECIDAGA?IB?GFG@BFFCHBHHBEICI@CGHCGDIADG1@GHDDHC@FFFIFADHBBB@GG
@>chr21:9831658-9831832-3
TCAGACGGTAATCAGNCACGTCGGCAAGCAGGAAGGTGGTGCTACACAGCTGTGGGGTGACAATAGCCTTTATGGTGATATGGGCCATNAGAGGAGCCCC
+
@B@IBGEIED?FA?H"A?FH@BHCDFBFBHEFBH@AC3DHCABHEAII?@@FI?ICIIBFH@H@HACEFFI$CFACIEH@ABFEGG?D<?BEAIECDA@G
@>chr21:9831658-9831832-4
TCAGACGGTAATCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTTATATGGGCCATTAGAGGAGCCCC
+
BBDAFFHD?I@CICCCBECF?H@F@IC?DBGHIIEFDEBBHGC?D@C@ADDH?DGBHGDHFFBEEE@GACAEIGBE,EBFDHGEHFEHEFDAF@DFFDGI
@>chr21:9831658-9831832-5
TCAGACGGTAATCAGCCACGTCGGCAAGCAGGAAGGTCGTGCTACACAGCTGTGGGGTGACAATAGCCTTTGTGGTGATATGGGCCATTAGAGGAGCCCC
+
EBAEBE?IA@FF?EGGEED?-BICA@B?GD@ICDBECG??IDI?HEDGDABDHHDA?CBH@@CGBBDBHCIEFH@?IIICIG?FFBGB?FF@F@AHGECB
@>chr21:9845011-9845166-0
ACCACNATGTCAGCTGGTGAAAATAAACAATTAAAATTACTTAATACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGTT
+
C@CID5BAEEB?FC@CCDI?D?GDAGCIEE?BCAGADAAHBE@FIH@IGG@GCIEFAEBIG?HD@@?EBFBF@IIGF@C?BBAHGGG@?GHIA@GAGA@I
@>chr21:9845011-9845166-1
ACCACTATGTCAGCTGGTGAAAATAAACAATTAAGATTACTTAAAACTACAACAAATGGGATCTGTATTTAAACCTTTTTTGGTCTATCTTCCCTTTGTT
+
@?HCFEFEFH?GICCFF@GEDE??HDGDAHGBBG4H?@HDIG?EGFGE*B@DGHHDAHGIDD?BED@I?BADFBBI,IHI@?C@AF@HA?I?H@@BFGEB
@>chr21:9845011-9845166-2
ACCACTATGTCAGCTGGTGAAAATAAACAATTAAAATTACTTAAAACTTCAACTAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGTT
+
HEEBDFB?AC?EGC?CIE@C?EHH@?HD@GAAGA?HDIGAFFEDAH?FIF?AD>H?CF?AG?IHEDCFBBGEICB@IFEABBGD?FHDEDF?EEEFFFAH
@>chr21:9845011-9845166-3
ACCACTATGTCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGCTTGCATTGTTGGGATTAGAAAAAACCAAGGGAAGATAGACCAAAACA
+
BEEGH?IE@DFIFIDDBC@@GGA@GCIIC?A@ADDE@EDID@IHAGGCG@@G9@?FIBI*IE?EGGADHAFGF??AA?6EDFIAEC@IB@CBF?AED?@?
@>chr21:9845011-9845166-4
ACCACTATGTCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAACA
+
FGCBEGFEDHIHFHIACEHIBHHIGDEHBIEEHEEEB@IAGF?@?HBIG@@FI@A?@H@AG?G@I@@FABDBAA@BI@@IBDFC@HCG??CACD?G?A?A
@>chr21:9845011-9845166-5
ACCACTATGTCAGCAACCTCCAGTATGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAACG
+
EGD@AEGIBCGAC@AE@@AFAFCA0BGC?DACHAIFDFEIEFIECCIG@DCC?BGFACBIGBEEFIII?HHDHEGCDFCFGDECFHA?HEDI?HA?IAE1
@>chr21:9845011-9845166-0
CTCATACCACGCAGCTGGTGAAAATGAACAATTAGAATTACTTAATACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGT
+
BI@HDAEI?H?G@GIDCGFEIIEDI0AD@EFIBD8CEIIDE@HGIBBGD@EBBE@CAE@IBFBIBCAGCHG?@I?ECFEHCGAIGB@HEGHDHFGHDIEE
@>chr21:9845011-9845166-1
CTCATACCACGCAGCTGGTGAAAATAAACAATTAAAATTACTTAAAACTTCAACAAATGGGATCTGTATNTAAACCTGTTTTGGTCTATCNTCCCTTTGT
+
?CICC??AIBGH?GIAAFCIFFBBAIHEI?CGCGHAHHB??@A?DA?FBBFFCCEDBG@GDH?AA?BDE$@DH?FHBDB?HE@@CBI@GH2EDI@CCCAF
@>chr21:9845011-9845166-2
CTCATACCACGCAGCTGGTGAAAATAAACAATTAAAATTACTTAAAACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGT
+
BFFDFIFDEGH@CAG?CFG?DBIEFGEB?CA@??B??FEIEABFBDEGCDCEFCHIGCF@FA@FG?GEDCGF@C@@CEDII?EDAA@BEEGDDICB@I?D
@>chr21:9845011-9845166-3
CTCATACCACGCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAAC
+
IE?FE@?AB@IF?D?D?GCDF@CEIIDEDHIF@IG?@?HI@IEF?DH?D@BEAHF@EHHF@H@G???@IH@GA??IGFDGBIHFCB?EI@AHBEDCDG?A
@>chr21:9845011-9845166-4
CTCATACCACGCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGANAAAACAAGGGGAAGATAGACCAAAAC
+
D@F@BBBCHCA??@FHA?@GFHBFBECHECIHIA@?FEBFFCDHDIBAH@@D@-AI@FCHBDA?@FACEAHBD1CDHCFBE<FIHAAACBGEHFF@GBB?
@>chr21:9845011-9845166-5
CTCATNCCACGCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTCGCATTGTTGGGATTAGAATAAACAAAGGGAAGATAGACCTAAAC
+
C@FB?6D@BE@??@IACIHHBCFFHF@?ABICGCIFC?I?FACB?FDCFBHADCG3F?AF?F@CGC??@@ACAF.?EFFGA?CEDIBHDD@CFBF*CB@@
@>chr21:9845011-9845166-0
GAAGGTCCTCAGCTGGTGAAAATAAACAATTAAAATTACTTAAAACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCATTGTTT
+
CCGI@@IDGBDHICGG@?EEFCI?CAIHC@@DEGBDCHDEBDIDB?@FHEGFBC@AEEH@IBCEA?IGCII?BCBAGFEDA??EGF@@HCEII#I@E@FG
@>chr21:9845011-9845166-1
GAAGGTCCTCAGCTGGTGAAAATAAACAATTAAAATTACTTAAAACTGCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGTTT
+
FGCF?AIGHFB@CGCCACB@8IBBIBCBGGHHHC?@C7@AEIDF@C@<EA?@FHE?EACGDAGB?FB@BBDHFIB?HCHBBF@IHG@B?GABHBAG?E@E
@>chr21:9845011-9845166-2
GAAGGTCCTCAGCTGGTGAACATAAACAATTAAAATTACTTAAAACTTCAGCAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGTTT
+
@@A@CDAH?BDB@H@G@BGF9DG?IGB?FFCEHDFABHAAFHBBGDHICI8D(B@D@DDEAHICE@IB?D?EF@D@HE@CBA?@AEEGEHDIB@DHGBEG
@>chr21:9845011-9845166-3
GAACGTCCTCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAANAAAGGGAAGATAGACCAAAACAG
+
@HB/IBGFFIFFI@EAG@DEEHBA@GEGEBGIH@EEFHH@EDBI@AB@GCGGGCBBAFA?F?GB@DECCC@CBI@@(ICBACHEDAIEB?H?D@CD?G?A
@>chr21:9845011-9845166-4
GAAGGTCCTCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAACAG
+
FE?CDCFHHGIF@IIFI@BDBGDDCHAC?EAHAFHHABIHEIIBEDA?DH@IEF??FFFEC@@H?EGBBGBCHIG?BFDHEGDEGBH@GCA@I@HCDCG?
@>chr21:9845011-9845166-5
GAAGGTCCTCAGCAACCTCCAGTCCGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAACAG
+
ID@H?HEEBDB@DIGBAHGEBBCB4FAEBIBBHDDHAAFH@ACEBDAI@HHHGDEIFDBDEADA??HGH@CED?CGC@CGBFDAAF@DDFCF?GADCHI@
@>chr21:9845011-9845166-0
GCGGCGTACAGCTCGTGAAAATAAACAATTAAAATTACTTAACACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGTTTT
+
A@GHCBFIE?I?I)FH?IHCGGBAD@FAIAF@HHHBCCCDCF-G@?EDBEEDH@BHE?DA?EGCBHAGAG@@EFBD@CGAGGDGCDCGIFEECDF@??BD
@>chr21:9845011-9845166-1
GCGGCGTACAGCTGGTGAAAATAAACAATCAAAATTACTTAAAACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGTTTT
+
@IIGGDHF?EGBH/CCFHGIFAEDFDHHI7BC@DBCGIIGGGDDEH??F@FBH@FFFI?HCAE?HAF@GIICEHI?ICFBCAEHHBDDDEDGB@EEAGFF
@>chr21:9845011-9845166-2
GCGGCGTACAGCTGGTGAATATAAACAATTAAAATTACTTAAAACTTCAACTAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTGTTTT
+
?FHGIHEIE@GFAAG@AF?/DEIG@?G?DGGAI?BFAFHFF@IBGCFDDCE1GA?DG?HFGA??AEFEFH?IGDDDDBCHH@?HICGFIC?B@@GHGB@?
@>chr21:9845011-9845166-3
GCGGCGTACAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGCGAAGATAGACCAAAACAGG
+
A@IAAAI@A@BGA?IDAF@HICIEE?G@I@AEGIBICHDB@?IDE??BD@EDAI@ED@HF?CICF?BDFGBDC?EFADFA5@EIAFCFC??@HDFACAID
@>chr21:9845011-9845166-4
GCGGCGTACAGCAACCTCCAGTCTGAGATTGCCCTTGATAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACANAGGGAAGATAGACCAAAACAGG
+
BBIDIC?DHEFADCE@A@GFFDCEDIAHCAAE?EBGGF%EE?4@DAECED?HB@CE?B@CFHDECEIIHCABHEFIA-GADAADF@FFEIC@EG@BEACC
@>chr21:9845011-9845166-5
GCGGCGTACAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAACAGG
+
??@@@EF@G@?E@@C@IC?G@?@EAG??@AIF?EBGI??CDH@@H?G?@EGHBAEIFE@EFCIH?E@IBBGB@HFAAIGD?HH?I@BDGG?AFD?IDG?E
@>chr21:9845011-9845166-0
TCAGACGGTAATCAGCTGGTGAAAGTAATCATTTAAAATTACTTAATACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTG
+
CGC?AAGI?@E?DABIFFAAII@B&BCD&IB:FCECFF?BDBC@GBA?FGEDEA@A?GIC@@CH@?BCGGC??CBDIGCC?FCFDIGEIAE@C@HIDIG?
@>chr21:9845011-9845166-1
TCATACGGTAATCAGCTGGTGAAAATAAACAATTAAAATTACTTAAAACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTG
+
HC@9DGBBCIHAF?EF@G@?EC-?DADEIEFFIEED@G??@HBCIDB?IFCEHDD@BB@HA@H?FACA@?G@FFDIGF@?CFIBACBD?FIGBB?IGFCC
@>chr21:9845011-9845166-2
TCAGACGGTAATCAGCTGGTGAAAATAAACAATTAAAATTACTTAAAACTTCAACAAATGGGATCTGTATTTAAACCTGTTTTGGTCTATCTTCCCTTTG
+
FDG?FDBAEFFDIIIIDAG@EA?BEEBFA@FDDEHBBIAB@GHCAIE?AC?IB@HIDB@@F@?G@FFCADICCDFGA@DEDCCD?FI?EFCBGE@HACBC
@>chr21:9845011-9845166-3
TCAGACGGTAATCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGANAGACCAAAA
+
I??F?F?BEABHBFHHHE??BI?D@HFFBDH?HD@ECEDAA@GC?@DDCA@AD?@DGE@?DBD@D?@EFICDE?CHGEB@DEDDDFFHG?=G?HF?@DFD
@>chr21:9845011-9845166-4
TCAGACGGTAATCAGCAACCTCTAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTCTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAA
+
HH?@DFBDC?A@?DFG?DGD?A3DHGFFIIDIEBH@IH@CAFGBFBCAG?F?AHAFABGIIC2FBE@AB@?DFAEIBDEB@?BDHG?GC@C?@@EGIGFG
@>chr21:9845011-9845166-5
TCAGACGGTAATCAGCAACCTCCAGTCTGAGATTGCCCTTGACAGTGGCTGAGGTTTGCATTGTTGGGATTAGAAAAAACAAAGGGAAGATAGACCAAAA
+
ECFI?@B@?EGHAF@IHHG@IBGAGFF??CFG@B@G@BIEDFGA?GIE@BDCCHC@EHEGCEGHFH@FE@BBFIA@@FBFBGIAFEHFHDCGFBIB?BFG
@>chr21:9846184-9846245-0
ACCACTATGTCAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAN
+
?BDC?@E@E@HG@@ICBABDDB@DGCCGGDHCFB@I@CGIEIFHE@CI@ACFCA@CEDEEBEHH@H@C?HC@@FIF@DH@EHAGI?DHD@BEFCEBACH(
@>chr21:9846184-9846245-1
ACCACTATGTNAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTTTCAGGGGAAGAATCTAAACAGGATGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
GDHCIDIEB@*EBGA?GD?H?EIHH?@ABFC?AIDE@EDECHIADEHEAFHH@AFHD?@E@E?@B@GF5FA@AGCB@AEIGBFFDEGHCI?GFGFGEDGC
@>chr21:9846184-9846245-2
ACCACTATGTCAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTTTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAGAA
+
DD?AEF@F?E?EG@FIHBD?EIFG?IIGEGFGEAEFAGHHA?IIIBE@EH?FEGAE4IGB??FGGB?A@FEEIHABAEBFEC@BIEHFEAAG@GCGA7@I
@>chr21:9846184-9846245-3
ACCACTATGTCAGCCTNTTTAGATTCTTCCCCTGAAAATGCTTTATCTTCCTTTGCCAAATGGGCTGGCTAAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
@DBFE@BGICAGI?DB'HEHGEH@?DCII@@?GDCAC@EH@?DHH@DDB@??ACFDF?@IF@EFB;DGDD#FC?GEHBACCBHGECICHFDBAG@FHHAC
@>chr21:9846184-9846245-4
ACCACTACGTCAGCCTGTTTAGATTCTTCCCCTGAGAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGTCATCGGAAGAGCGAAAAAAAAAAAAAAA
+
IGE@?ID=GEHGEE?FIEDI@HGEFFAC?DD@CABF?DCDHEDGA@EABEDCFGEDHGG?EF@?AIEFG@@>0FI@F@GBFIIAI@EGCFCGHIFHIFI@
@>chr21:9846184-9846245-5
ACCACTATGTCAGCCTGTTTGGATTCTTCCCCTGAGAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGAGATCGGGAGAGCGAAAAAAAAAAAAAAA
+
IGBFBEFGFHAFDIIE@FGC/H@H@CEDA@CGGAHECBECIGAF??D@HHBCG?IC??DBG@FHH@DG?FCFCFCI?C!AD@AFEFGDIEGC@AFCHIGD
@>chr21:9846184-9846245-0
CTCATACCACGCAGCCTNCCCATTTGGCAAAGGAAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
G@BDGB?EH?@GG?GG@=ICHGBCDIEDBAC?@D?GCIGDEH?BIF?IA?ICIBB@EHACFHCC?CEDGCFFGAH@FEDEAGDHIAI?FCBI@AI?FB@?
@>chr21:9846184-9846245-1
CTCATACCACGCAGCCTGCCCATTTGGCAAANGAAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
@BBFEEABIEFFHIBABEF@EHDI@CH@?DG2@DIBIEHIAA@DA?D?H?FCBDCAH@?@HIABDCHAFEHCDHDF@?EEBAGCBBD@B@DAIH@CIEBD
@>chr21:9846184-9846245-2
CTCATACCACGCAGCCTGCCCATTTGGCAAAGGCAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCTAAAAAAAAAAAANA
+
ICEDGBEFCDECIGGAIIFIHEH@G?IEEEAGI.A@DGFBBF?C@FCFHHCADFDCBHIF@FH??FGHBGGGAB.BABB?IG@IF8EGBB??CIIDGD.G
@>chr21:9846184-9846245-3
CTCATACCACGCAGCCTGTTNAGATTCTTCCCCTGAGAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
IBEBA?IEE?IAFII?CA@A,HFCA?I?IBIAHFGBC?GAH?@C@@@C@IACIDDAFHCCEEFDHAC?CHHIIABGGFEDC?AFI@DHC<ED?A@AGGBD
@>chr21:9846184-9846245-4
CTCATACCACGCAGCCTGTTTAGATTATCCCCCTCAGAATGCTTTATCTTCCTTTGCCAAATGAGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
IAEIADGEFGBEAAH?CACIBGDFID(C+HCBHG>FB@F?F@FAE@FI@F@GCEEEDBD??AG2FABF?ACG?GFEHB@@ABCECDF@B??EICAHFBHF
@>chr21:9846184-9846245-5
NTCATACCACGCAGCCNGTTTAGATTCTTCCCCTGAGAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGAGATAGGAAGAGCGAAAAAAAAAAAAAA
+
#CGABFIFBH??CGBC0EECC??DGBEEEGECFFCE?IE@CF@E?DAIEFAI@AE??IDEDHECHABIDEBBCIGH3BADGBBEF?E@D@CGDB?ADHDD
@>chr21:9846184-9846245-0
GAAGGTCCTCAGCCTGCCCATTTGGCAAAGGAAGATAAAGCTTTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
FG@DFCGIFDBHDEIG?@IDCDCIIAG@@CGCCEGHGEAEC1FH??HA?AFABHEB@FDBIABEEDBFACA@HA?GDDDCH@HGCEEAAHI?C?BI??FI
@>chr21:9846184-9846245-1
GAAGGTCCTCAGCCTGCCCATTTGGCAAAGGCAGATAGAGCATTTTCAGGGGAAGAATCTAAANAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAG
+
?FHGHD@ID?@AFEDAAAGB@EDEDC?FD@B1@AFCE6GEFIC?CFHBE?HF?CIHHEIFDHG*AEFCDG?GD@CBBDGIFBAIEBAFBBDGC@H?IHD-
@>chr21:9846184-9846245-2
GAAGATNCTCAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTTTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
GHFD5@&AHHF?F?HCAGD@DBIABE?@IBA?FABAB?IFBHCFD@BA?IGHCBEEEFG?@IAFFACCFCCGAAFG@?FB@GGBFHEFF@GHGFDA?DGC
@>chr21:9846184-9846245-3
GAAGGTCCTCNGCCTGTTTAGATTCTTCCCCTGAAAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
ICEFGG@@BH0DFACACGDHBHCBCDCADFB?IBFAIBE@B@HIBGEHBHF?FIBHC?BBECCGHCEEBI@HIBFHIGA?CI?FDE@HIIC@@H?B@EGB
@>chr21:9846184-9846245-4
GAAGGTCCTCAGCCTGTTTAGATTCTTCCCCTGAGAATGCTTTATCTTCCTTNGCCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAT
+
HIGB@CB@@EEEGB??A@HDDGI@?HAGAGE?ECB@AIHC@EEEIIDE?BIB-HFAHH??GDIAI@EEH@CEI?CHE?CFDE@DCE@C@FAFAD?AIGI+
@>chr21:9846184-9846245-5
GAAGGTCCTCAGCCTGNTTAGATTCTTCCCCTGAGAATGCTTTATCTTCTTTTGCCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
AH??FGACGDFFDD?F(@BAHHHIBB?CEF@FCEGAEHBAEFEIBIG??<E@DD@@CDIEIFFFAI?IIG?CFCGFG?FEI@FCCAHEE@@EA?IHAC?C
@>chr21:9846184-9846245-0
GCGGCGTACAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
IG?EADEAGFBIB?HIB@@CC@A@GEBDCGD???HBCAD?AHDCCIDFCD@E?FIGB?@DGGGCBAE?HICAABFBACDCEHIC??C?B?FF@@DBIFBI
@>chr21:9846184-9846245-1
GCGGCGTACCGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
DC@BIAHCA6CBBA@?CFD@AIH@IDIDHCCAEDEF@FGIHE?EGEBCI@IFFG?GE3EDC?HDHDHGHCHI?@?FBGB@C@CG?FBEABFG?@FGACAH
@>chr21:9846184-9846245-2
GCGGCGTACAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
B@@@HCFA?IDB?C@DB@DEADEEH@?IBFGDGC?FHDD?FIBFAAECAA@HGHIAEHFABEBFDCHDGAAFDFCHHA?GGCCHCD??CFED@HCCDBDE
@>chr21:9846184-9846245-3
TCGGCGTACANCCTGTTTAGATTCTTCCCCTGAGAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
2DCBDFADGC$IACB@I?GBEF?IEGCBHICFGEDHHABCFAI?@F??@@FF?B@GGDD?GG??FEIBBCI)FDCECFBAFE?EHBAG?@AGG?H@HEE@
@>chr21:9846184-9846245-4
GCGGCGTACAGCCTGTTTAGATTGTTCCCCTGAGAATGCTTTATCTTCCTTTGCCNAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAGA
+
CEG?E@BIIECIFIGGA@ADHE@(HCI?I@?IFCBE?IIDCIBAEHEHB?IGCBC7GAGFGBCHCICCFCHGEFAIEFDFIIE??IE@G?FFIDCFBF)C
@>chr21:9846184-9846245-5
GCGGCGTACTGCCTGTTTAGATTCTTCCCCTGAGAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
H?@'EC@E?1EIDFHEHCGHGG?I8@HI@?GFCFDAACIBHIAH?GAEGCEH@EFIAGGE@IF?EIBEICI,C@GF@EDHFIHH@B?CGDI?AA@CH@GD
@>chr21:9846184-9846245-0
TCAGACGGTAATCAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
AEEIIBEHG?ABI??FIFCHECICGACCBDCFGDFII?HHBCIHHBEDBBIGHF?A@FECEGD@EBHADCFABHFIC@HDIF@AA?DIAHHDBFDAAFHI
@>chr21:9846184-9846245-1
TCAGACGGTAATCAGCCTGCCCATTTGGCAAAGGAAGATAAAGCATTCTCAGGGGAAGAATNTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
BG?DFC@FI?G@?IH?HG?FCFDHH@FG?G?DFADCI@CDCAACIIAEBGDHDA@EHC@IG"DE?FDIEE?F@AGHFCAG?HGFEH?HFBDAEHEAHIFF
@>chr21:9846184-9846245-2
TCAGACGGTAATCAGCCTGCCCATTTGGCAAAGGTAGATAGAGCATTCTCAGGGGAAGAATCTAAACAGGCTGAGATCGGAAGAGCGAAAAAAAGAAAAA
+
GAH?IB@@HD?CIEIHEG?@BDB?AC@AGC?DI?1IADEI0ECACC@?D@EIH@HGEDA??HBGAIGCF@HGGBEBBAIECFEHHH@EGAB?C@8I?CFB
@>chr21:9846184-9846245-3
TCAGACGGTAACCAGCCTGTTTAGATTCTTCCCCTGAGAATGCTTTATCTTCTTTTGNCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
FDBFBD@BD@A4DFGGEGF?HFDCGG?A@IFGABCGBECBGHFB?FH@HDIC6EIBF,GA@?BFFIHFGIH?I@GIC?DAF@I@IBBF?BHAHGCEACAE
@>chr21:9846184-9846245-4
TCAGACGGTAATCAGCCTGTCTAGATTCTTCCCCTGAGAATGCTTTATCTTCCTTTGCCAAATGGGCAGGCTGAGATCGGAAGAGCGAAAATAAAAAAAA
+
@BBBDCHFEHDI@?BEI?IG*EAHE@DE??AGIFAAEHFCHEDCEBE@@ED?FEFA@AIHBFEBBDGECBACDDAAB??F=EAIGBFADII/BIF@I?DF
@>chr21:9846184-9846245-5
TCAGACGGTAATCAGCCTGTTTAGATTTTTCCCCTGCGAATGCTNTATCTTCCTTTGCCAAATGGGCAGTCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
EEHFC@GGI?E@?G?GFIBHFE@DBGE7HIBGG@EF0I@EDECI+H@F?CBDAFH?C@GC?HICCCF@C8@F@BGIDFFD@DGCCGFI?GIDICGBDE?B
@>chr21:9846242-9846350-0
ACCACTATGTCTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGCCTTGAAGGCA
+
BFHA?CD@D?FD?@@EBH?C@CE@CG@AFBI@EECCCFF@AE@FAI?GH?GEEICAEBDDIHADBIBAG@?CD?HHCGCEFHH@EHGHFBCAIBFAGEFA
@>chr21:9846242-9846350-1
NCCACTATGTCTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGCCTTGAAGGCA
+
#?CCDHIHIGCEIBIDHF?A?C@DGIDIBDB?A?FABD@G?D@GGAEECC?GIHG?IIFB@ICC?CD??IIEAECC?BAI@FG?E@EACEDC@?HE-E?D
@>chr21:9846242-9846350-2
ACCACTATGTCTACGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAAGCCTTGAAGGCA
+
BGFEGC@@IB?C3GBBHHD/HEEEFFIH@ADHIBIFEACCFDDCGDAADCDABD?IEBCD@B?GF@H@GGCHGDDEGIGF??G?CDD-CE?EI?BIAGFG
@>chr21:9846242-9846350-3
ACAACTATGTCTGCAAAGATTTCTGAAATGCCTTCAAGGCCTTTTTTTAATTTTCTTGGCTATCAGCACCTATCTTTTTCAGTTATGCAAATGTCTCTAA
+
?H(@F@DHGFIC@?BHAIHAEG?@IHA@BHHBGF?CBDGDBBGE@GB??EEEAIAEEECBEH?FDHCAFBH?"@@HACGFGGBCF??G@DF?FBICG?DF
@>chr21:9846242-9846350-4
ACCACTATGTCAGCAAAGATTTCTGAAAAGCCTTCAAGGCCTTTTTTTNATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAATGTCTCTAA
+
EFEEEIACABE*@IDHGCH@CF@EFFC?)@IEFEG@?CEBAGIHCCCA=G?BHAHBC?GBD?@E?GDDHFDGIFE@GAHED@DIBCBGCC?FDBDC@IAG
@>chr21:9846242-9846350-5
ACCACTATGTCTGCAAAGATTTCAGAAATGCCTCCAAGGCCTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAATGTCTCTAA
+
HCIBBGGB?EGGC@?CH@BFA?D9CBAFIE?FA8GD@FEBF?GC@IHGDC?CIDHAGAAB@CHFB@FIEBAE?HI@EEDIFIEHEGEGBFEIIBE@DCAI
@>chr21:9846242-9846350-0
CTCATACCACACTGCGGAGCAACCACTTATTGGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGCCTTGAAGGC
+
??IDIFDEG?2C?@DHDIH@@B?@?FDGDH?<DCGAE@HIB?HB??FEE?BH?BICCGIICBEE?HHFGHAEHBFF?I?BF@ECIHAEEDEGBGIF@FID
@>chr21:9846242-9846350-1
ATCATACCACGCTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGCCTTGAAGGC
+
(@DHA?DEEAECA?HAII@D?EHD?IBGFED@CGBB@?CG@@BFIFBBDB@GD@DECDCBFIADEFABCDEEFADBG?FEHF?HICDEGAB@FECFHA?H
@>chr21:9846242-9846350-2
CTCATAACACGCTGCGGAGCAACCACTTANTCGAGACATTTGCATAACTGTAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGCCTTGAAGGC
+
D?CA@C+D@AHEHE?CGFH?BHDEDFACG,G3CI@FBBIHBHHD@DADGE3IEFDBFI?AI?DC?G@FGABCDC?@GH?DGCFHIID@BBI@A@AG?DID
@>chr21:9846242-9846350-3
CTCATACCACGCTGCAAAGATTTCTGAAATGCCTTCAAGGCCTTTTTTTAATTTTCTTGGCTATCATCACCTAGCTTTTTCAGTTATGCAAATGTCTCTA
+
@C?EHG@B@?GBIADHAHCF@?F?CHHBCG@G?IFBAGBA@EDBAIIEA?H??C@EG??@?GCEAA8A?HFDGFEBG@H??BIDHC?CCCIFIIHIFB@I
@>chr21:9846242-9846350-4
CTCATACCACGCTCCAAAGATTTCTGAAATGACTTCAAGGCTTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTTAGTTATGCAAATGTCTCTA
+
G@GHGCICDA@FG0BC?EDHFAFAA@IECCH3BGAEGACCC2IFACGAABFCIHDI@?IIGDFFGG@A@HBE@F@FB@ID%EBFIHAHGAE@IDDHDBHE
@>chr21:9846242-9846350-5
CTCATACCACGCTNCAAAGATTTCTGAAATGCCTTCGAGGCCTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAGTGTCTCTA
+
AI?GAFA?AEAF?-HEGGCHCGIEFHBCCDBBEBF?$BFECGB?DEDD?G??EID?BCEG?GBDAGH@CBDGIE@ECBHAIBAG@ABCD?D9AAF@CFFA
@>chr21:9846242-9846350-0
GAAAGTCCTCTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGNGCTTGAAGGCAT
+
@@B&C?H?FBDDHEFFBCFC??DAFC?FGF@B@BDB?@I?ACGGDDIAHDDBCCIE?AFEHCG?EAFHD?F@IHFFIEFCECAA?HA-C@@AIAGHFIFD
@>chr21:9846242-9846350-1
GAAGTTCCTCTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGGCTTGAAGGCAA
+
IEFD2G?C@IEHEHGGDFCIFEAGBIADADCBF@AF@?IBEC?IFI@AFA@HGG-?ICE@GHHG?AHEC?@AFEHHFIADGIFH@@CEBHHAFFDFAFC/
@>chr21:9846242-9846350-2
GAAGGTCCTCTGCGGAGCAACGACTTATTAGATACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAACTAAAAAAANGGCTTGAAGGCAN
+
BADIB?BHFFHCEDA@DDG??)IAA@ABGBGH:D?ADCHAHBIDH?GAGGCHGCHFDAECD??@E@IGAGFBDICFF5A?IEGCCC&@DBEIDECFCGI'
@>chr21:9846242-9846350-3
GAAGGTCCTCTGCAAAGATTTCTGAAATGCCTTCAAGCCCTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAATGTCTCTAAT
+
FBIIAC@G@CGI?GCDBDGIIFGCADCBFFH@DECGCAIIF@ICB?D@E??HFBIC@@@CCE?GC??AGHHD?CIFGG@GFA@IBCIBADI@DCDFBA@F
@>chr21:9846242-9846350-4
GAAGGTCCTCTGCAAAGATNTCTGAAATGCCTTCAAGCCCTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAATGTCTCTAAT
+
FEBDFEAFGB@?G?HIBE@'I@IGCD?C@DB?GAFFA?HGAGAABEHC?BICCCFEFADIGGBEHGEH?FIFG@F@?@HAIFEFII?GIFACHFDF?H@D
@>chr21:9846242-9846350-5
GAAGGTCCTCTGCAAAGATTTCTGAAATGCCTTCAAGCCCTTTTTTTAATTTTCNTGGCTATCAGCNCCTAGCTTTTTCAGTTATGCAAATGTCTCTAAT
+
GEBF?CCFAEF@DGDBI???@@GCFIHDDFC?HAECE@CF@H@?IBHDH@@HBB:?CGHH@FGGFH3HED@ACCDICFF@?GG?ECE@DGIIFGCHGGHI
@>chr21:9846242-9846350-0
GCGGCGTACTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGTTAGGTGCTGATAGCCACGAAAATTAAAAAAAGGGCTTGAAGGCATT
+
IEIGEFD@EDBDFAAIH?CI@GHGEB@?CA@@?@EH?EB?AIHBCH?@AG?GH0BEBCFGECGEBDCIFD"@CGIECC?B?EI?@IFHCCBHE?GAE@@D
@>chr21:9846242-9846350-1
GCGGCGTACTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAACGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGCCTTGAAGGCATT
+
IBFGFBECG@HAHAFAGE@@AG@GD?G@@EGCGE@GHG@&DABCEGGEI?E5F?IH@?H?G@BAECAA?EBE?FCB?CFE@ICIC?DDECDHBI?EDAIG
@>chr21:9846242-9846350-2
GCGGCGTACTGCGGAGCAACCACTTATTAGAGAAATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATCAAAAAAAGGCCTTGAAGGCATT
+
I@?FAAIA?HAHDAAGBEBI?HFDFEIEGICCC*FBDFB?CGGF@C?CH@G?CHFI?CAFIBBEEAEEB@E?EEFHF%FDFD@FCFEBF@BDGB?CHHBE
@>chr21:9846242-9846350-3
GCGGCGTACTACAAAGATTTCTGAAATGCCTTCAAGGCCTTTTTTTAATTTTCTGGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAATGTCTCTAATA
+
E@F@AHAHBG1DAA@EGFFEIBBADEIBE?ID?AGFFCDED@DGG@IFA?@II?0FHI?AEGDBHEIHA@IIABFABGCACG@GDF?D?GHHFGIHHBEF
@>chr21:9846242-9846350-4
GCGGCGTACTGCAAAGATTTCTGAAATGCCTTCAAGTCCTATTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAGTGTCTCTAATA
+
4AAAGFEHFHAIBFBB@HADGDEDIIIFC?GI@HAE)F?E2CEHI?DIGEHA@EHGIBAF?HIAIFEAEFFE@ID@@?EEE@CAFFAI#FI?H@EHG@@@
@>chr21:9846242-9846350-5
GCGGCGTACTGCAAAGATTTCTGAAATACCTTCAAGCCCTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAATGTCTCTAATA
+
HDCAC?EHFAAEI??H@EH?ID@C?CA-GGFGGIIBIH?BBHEIIDH@CFA@AH?FABAEE@IG@G@BHCAHBEEB@DHDDDA?I@EAC?GDGF@?E@F@
@>chr21:9846242-9846350-0
TCAGACGGTAATCTGCGGAGCAACTACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGCGCTGATAGCCAAGAAAATTGAAAAAAGGGCTTGAAGG
+
IC@ACADGIIE@@???B?CHC?FF1IB@H?FICH?CADBI?DHBBHIGDD@I@@@FI@GIBF#DDEHBHEIEDECHAGB?EG>?DDEABIH?I?A@FHFB
@>chr21:9846242-9846350-1
TCAGACGGTAATCTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGGCTTGAAGG
+
BIAF?ACCBBH@G?C?HBBDEFDH@F?GDBHBHD?@?ABHHCFAFCEEG@D@FAGBHI?GCGIFEEIBCA??BBH"IDCDCAD@F?ADGDEFFF@CHA?G
@>chr21:9846242-9846350-2
TCATACGGTAATCTGCGGAGCAACCACTTATTAGAGACATTTGCATAACTGAAAAAGCTAGGTGCTGATAGCCAAGAAAATTAAAAAAAGGGCNTGAAGG
+
DAH6B@EE?BAIFIGH?FEFDBGF@BHF?AHI@BADAGDGDEEBE?IBDDBAD@?IADCGAIA??IG?FHBDHAGHBBEDFA@B@DDDEBIA@"DDF@BF
@>chr21:9846242-9846350-3
TCAGACGGTAATCTGCAAAGATTTCTGAAATGCCTTCAAGCTCTTTTTTTAATGTTCTTCGCTATCAGCACCTAGCTTTTTCAGCTATGCAAATGTCTCT
+
?H?@GB?@EI@B?CHIHE?H?AB?EC?DIFEI@DEBBHB?C(IABEG??HFHB-DIFHB.@I@G@IH@EA?H@AIA?F@CCH@@)DG@?CEHI?GGBIF?
@>chr21:9846242-9846350-4
TCAGACGGTAACATGCAAAGATTTCTGAAATGCCTTCAAGCCCTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCTTTTTCAGTTATGCAAATGTCTCT
+
??AC?DBICBC-&BFIHEDFCGC@F@IA?DADHIA?IBA@EEFIFGFFCCE?AHAE@GGFGADBHDGEBCAACEFAHCIBFB;?IHBGAF?@FIABICFI
@>chr21:9846242-9846350-5
TCAGACGGTAATCTGCAAAGATTTCTGAAATGCCTTCAAGCCCTTTTTTTAATTTTCTTGGCTATCAGCACCTAGCNTTTTCAGTTATGCAAATGTCTCT
+
BDE??F?DFCFFDGGBDBEI?C@GDCDG@?IHACFAHDDIGCAGFEIDICGGECAI?CBDFG?IDBFBGHCFHCBB=@IEGCFBAG@?@BCFFHE?EEAG
@>chr21:9849889-9849952-0
ACCACTATGTCAGCCTGTGTTATAACATTTGGTTCATAAAAGGGAGTGAAACAACAGTACGAGAGAAGAGCGGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
IICDBAFDAC?H@FAA@AFD?D@F@GADDAEG@?EDBAIH?D@HGGGHGCF@C#IHFIC??@BD?@G@BF@7@BABBDI@HAEDIAEFAIFFABFIFCF@
@>chr21:9849889-9849952-1
ACCACTATGTCAGCCTCTGTTATAACATTTGGTTCATAAAAGGGAGTGAAACACCAGTACGAGANAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
ADHIHDCIEBBIFBCEAAHGIGBE?AI?DAD@AIIF.C?HHEEBHEFEDFGABAAC??GHBD@C!FCEFCGGEGHGI@IDBFDABBGAGBHBCGFBCDEH
@>chr21:9849889-9849952-2
ACCACTATGTCAGCCTCGGTTATAACATTTGGTNCATAAAAGGGAGTNAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAACGAAAAAAAAAAAAA
+
@D@EGE?FE@GE@HCIF4D@?@IEBEF?EC@AI8IAEA?HE@AHG@E#HIBACFEGGEF@DHDIAAAE?FIEGCG?ICE@FIAA6@IEBCEF??GGFBI?
@>chr21:9849889-9849952-3
ACCACTATGTCTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
BHFDCEEGEE?CFECDH?D@E@@AIA?D?CI?CGDEI?CFC@FB?BCHFC?GDCGDEEF@FEF?DF?IHICBCEECIBBEHH?GF@G?HDEBED?E?AIC
@>chr21:9849889-9849952-4
ACCAATATGTCTGCTCTTCTCTCGTACTGGTGTTNCACTCCCTTTTATGAACCAAATGTTAGAACACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
EDF@>BABHI@GBCHHGHGGDGAD?FGEFBHCA@6BBF0HCHBBIGFH@?G?D?B@G@AIG4CF@@CGFADF@AC@DIGGDF?H?G@DFEFBFHE?G??I
@>chr21:9849889-9849952-5
ACCACTATGTCTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAATACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
GIEA?@A?C@EAADGGB?HGGC?GGIBGDABG@?FCFAD?HHH@BEE@IGH@FCAHDD@IGD@?$HGI?6EG@ADAFIEGDHCAFIBDH?@F?@AIID@B
@>chr21:9849889-9849952-0
CTCATACCGCTCAGCCTCTGTTATAACATTTGGTTCATNAAAGGGAGTGCAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
IAIGF@F?3@0?HDFBIAHDGDI@HDHA@IDACB@FGC,ICIFGHHCFD8C@DBHDGCFEGEBFB@HBDFAFHBIAGF@AGCGDFFABGFAGFA?DEF?D
@>chr21:9849889-9849952-1
CTCATACCACGCAGCCTCTGTTATAACATTTGGTTCATAAAAGGGAGTGAAAAACCAGCACGAGAGAAGAGCAGAGATCGGAAGAGCGANAAAAAAAAAA
+
@@CICIA?DB?CIGECBBHAHEBHHCAEDFICFCHDA@@EIE@BGCGEGCFB8?D@GH(FGBAIB?G@HDGFIEF?AICDGIBAABEFH'GEHGGFDDDH
@>chr21:9849889-9849952-2
CTCATACCACGCAGCCTCTGTTATAACATTTGGTTCATAAAAGGGAGTGAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAGAAAAA
+
CDHBIBCF@FBEICCCIA?AGIBB?FFEBHIE@DEA@DC?HDAAEBEEGCEFCFHFGGDGEG?DF@GEA?HEBIEFGE@C@FE@GAEHFDCA@I-FH@C@
@>chr21:9849889-9849952-3
CTCATACCACGCTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACAGAGGCTGAGATCGGAGGAGCGAAAAAAAAAAAA
+
I/F?HDIEIHGH@EGHGBAGEFBCCI?@?IGDFFIIHFIEBICDECBEHCBCD@C@AFCI?DDAIC@ID@F@CEIEI?GHCH%ECEBDAACBC?@@ACFH
@>chr21:9849889-9849952-4
CTCATACCACGCTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACAGAGGCTGAGATCGGAAGAGCGAAAAACAAAAAA
+
AGDD?ACGE@AIDFHIACEHDACD@GGEAEABBCEGD@H@EHEBEG+CE?GBHA?IED?@I?HEHEEI@HCH@FCFAH@BGDE?AGEBCEGCA,?FEGAE
@>chr21:9849889-9849952-5
CTCATACCACGCTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACGAAATGTTATAACAGGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
BC@CDBBEDDIHFG?B?EBAF?HIIFCADECGCEIIF@ECAD@?@CECHCHFD5IBD?@EGBA@@EDC!EAHEH????@ACCCI@DFGA@CDICFHF?DC
@>chr21:9849889-9849952-0
GAAGGTCCTCAGCCTGTGTTATAACATTTGGTTCATAAAAGGGAGTGAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
C@DGHE?GH@@CDBF?@CGHHBHGH@GFIF@?IFGG?CDFIAAHDEDHHH@IG@EHGDAEC?IFHG?CAHCDCB@BIAH@G?GH?EFBA??DIG?@CHAA
@>chr21:9849889-9849952-1
GAAGGTCCTAAGCCTCTGTCATAACATTTGGTTCATAAAAGGGAGTGAAACACCAGTACGAGAGAAGCGCAGAGATCGGAAGAGCGAAATAAAAAAAAAA
+
?AFDF?@@B;*FAFBCE@B,@D??FHCBEDGIIHF@HFA??EHCFDG@EE@GGIGBFIGEF?IFBGG0FBBDEIEDBIH@BIEGAHDCF=FDAI@FHHA?
@>chr21:9849889-9849952-2
GAAGGTCCTCAGCCTCTGTTATANCATTTGGTTCATAAAGGTGAGTGAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
FEI?AC?BBHBAFGBADED?CGG<ICB??DFIBGCBBAC3G2@FE?DF@?FEEFE@@GDBA?BI@HHBEGBC?EBIGBE?GGAHADHDIDDDHCAEADBA
@>chr21:9849889-9849952-3
GAAGGTCCTCTGTTCTTCTCACGTACTAGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
IDCCH@@FA?EG!I@II@@C2FDFA@A-CE@@IIB?CDE@A?DCAG?AEDEHH@?B@GEHHEBCIGGEBFC@EB?AA?AC??CHB@?DIA@AF?GDADEC
@>chr21:9849889-9849952-4
GAAGGTCCTCTGCTCTTCTCTCCTACTGGTGTTTCACTCCCTTTTATGAACCAAATATTATAACACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
FDGFGEACECFGBEDD@BF?IF"FC?GHF?GFD@EFFFEAEEEFC@?CCB@B?BAB,@CBDBAI?EEAIGF@C?IDIBIGFEBI@BDHH?FGDDCIB@IH
@>chr21:9849889-9849952-5
GAAGGTCCTCTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
AA@HGEBE?FFAAHFFGG@ICFHDI@DGCFECGH@A?ADCDFCG@BIFHD?EBEEIBBHCFAC?AD@@@AGDGECFIIGB?DCGCFBHH?GBACB@F@EB
@>chr21:9849889-9849952-0
GCGGCGTACAGCCTGTGTTATAACATTTGGTTCATNAAAGGGAGTGAAACACCAGTACGGGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
AD@FHFCBH?HFHHD?ACCI@?BBDD@AHB@?B?E>@C@DFCGCCHB?FDFHF@@AGFC-A?CBE?FABGHIGEGHHFA@IIHDBEHCC@IBIF@CHE?G
@>chr21:9849889-9849952-1
GCGGGGTACAGCCTGTGTTATAACATTTGGTTCATAAAGGGGAGTGAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
A@@C)?B?AGIEADC@GFA?HG@HFB?DFIFGE@FBD?$FFEIBHG@EIAFGC@F?IIGDAFDACG??AFBFIDHDA?@HB?G?F@EBHB?HBHFAD?@E
@>chr21:9849889-9849952-2
GCGGCGTACAGCCTGTGTTATAACATTCGGTTCATAAAAGGGAGTGAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAANAAAAAAAAAAA
+
I@IAH@GAABHFFF,E@IECFFA?I?H-BIIGHIBD@GHFGABFCBECH@HAEHD@I?@EGFI@FEBAG@DG@BDEG?DEFBC@FDEI%FGAFGDEBEID
@>chr21:9849889-9849952-3
GCGGCGTACTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
ADCHC@B@DB?DADHCHEB??B@ICAII?DFI??AFCC@BHGGGHDGI@HFIDAGCGFE@@ICAGI@DGIFADIE?@DGIAGC@F@FFHCFAGBEFCBDB
@>chr21:9849889-9849952-4
GCGGCGTACTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
?AEGHB@BBHGDFIBCGGEDG@GFIGEDFGCH@FAGBAEHDGEB@A?BGEIGDDDI?@DCFDCBBHDEH?CBGCEI?BGIDAAAE?FCBEFGAHGBEEHG
@>chr21:9849889-9849952-5
GCGGCGTACTGCTCTTCTCTCGTACTGGTGTTACACTCCCTTTTATGAACCAACTGTTATAACACAGGCTGGGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
AG@IFI?DF@@FEGDI@I@ACDDCGFGECEC?'CBFI?@BFB?BFIGEDIA?H#FADD?FECEBBIGHFA?8BFA@?B@?AAH@EIHG@IBCBE?ABCC@
@>chr21:9849889-9849952-0
TCAGACGGTAATCANCTTGTGTTATAACATTTGGTTCATAAAAGGGAGTGAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
?GHI??DG@DHIBG7A1??HGABEAC@C?CGC?FCH@IADBFDB?FCEDDF?BHC@E?CGH@CHBC(D?IDF@HIC@GCEEGI?@A@F?FCFFDAAFAG@
@>chr21:9849889-9849952-1
TCAAACGGTAATCAGCCTCTGTTATAACATTTGGTTCATAAAAGGGAGTGAAACACCAGTATGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
@DE<F?D?BEAHFEHHEFDBBICIG@B?CHHDFBCFBEAB?BFABAABDH?ACEBI??BDH<IAABDDBFEGDDBC?H@CAACIAGB@H@??H)ID?B@C
@>chr21:9849889-9849952-2
TCAGACGGTAATCAGCCTCTGTTATAACATTTGGTTCATAAAAGGGAGTGAAACACCAGTACGAGAGAAGAGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
@IHHDEC@AIFCCDIAFCC?7?EAIDHEBIIEIAE?FCBIGEI@FCDC?D?A@AI?EGHE??BHDIFDGEBIEGBFE@DBBIGGGI@G@HF?ACGCI?IE
@>chr21:9849889-9849952-3
TCAGACGGTAATCTGCTCTTCTCTCGTACTGGTGTTTCACTTCCTTTTATGAACCAAATGTTATAACAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
@G@IAEAEE?A@BBA@HEG@G*?HFEI@GHI@@FG?IACFC$IAFII?CFFC@?@FCAIDC?@BFFHGBAHGHIB?IC?BFCDGDI@DDGGFGDFACHAD
@>chr21:9849889-9849952-4
TCAGACGGTAATCTGCTCTTCTCTCGTACTGGTGTTTCACTCCCTTTTATGAACCAAATGTTATAACACAGGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
CGEHCEDBCBGEDCA@D?DAGGCDBFE??C@BEGI7EAICDGD@@?FDBEEE@EEDFDCHAFC@DG>FDGEAGC??@A?GFBIGHBDDBD@HCDH@BGHA
@>chr21:9849889-9849952-5
TCAGACGGTAATCTGCTCTTCTCTCGTACTNGTGTTTCACTCCCTTTTATGAAACAAATGTTATAACACAGGCTGAGATCGGAAGAGTGAAAAAAAAAAA
+
FIDI@F@FCEFBCGCAFEF@EFD@@G@DIC#EEBIIBD?HGFHIA?CH?FA?H3F?IGFEC?@@HDGHICIFAGDC@?D?FFFDGAH&AC@HBFFEFABI
@>chr21:9849949-9850095-0
ACCACTATGTCAGCCAGTCCCCCTCTGCAACTCACCTTTCCNCTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCCTTGGA
+
FCCFBG@DACE@?FEHC?H,AAHCHCAC?DDFEDIDGIGIC"A@BIBDFFFEDIHFF@?@HIDBG@BEICG?C?CEI?IDCA@E@HA@HCDHDCID??E?
@>chr21:9849949-9850095-1
TCCACTATCTCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTNTTTCTCCCAAGCCTTGGA
+
(I?BHCCF!CCIHHC@B@BBDDD??IBBH?GIDFIC@D?EAGFGIF?HHEG@CIIBCIEAAAGI@@EIECAFGGCBIHEEG5DIDGADCB@?AAB?BG@F
@>chr21:9849949-9850095-2
ACCACTATGTCAGCCAGTCTCCCTCTGCAAATCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCCTTGGG
+
FAAHDIHE?EEBFIGAGCAHGA@BCEIEDD8CDDEA?GD?IFFHD?CDGA?BBC@B??EICAAIIIADGFFEAIIGCIDEIA@FEAIGHCCBCIHFCC@=
@>chr21:9849949-9850095-3
ACCACTATGTCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCTTCTTTTGTGCTAGCTCCAAGGCTTGGGAGAAACAGAGTACTCTCCCTT
+
GDDE?FHIC??@?DA?BHB?DIFHDGHEFA@IFHEA@DEDDH@CGD?CDBC<EHD@@?EDDEHEA?A@EDDEBDAAHHBIEE???BHIAB+AEEG?@EGD
@>chr21:9849949-9850095-4
ACCACTATGTCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAAGGCGTGGGAGAAACAGAGTGCTCTCCCTT
+
HABE@FCEAGHD@@IC?@GGCBEBCCDD??B?AG@@BE@?ICHDFI;CCDEGCD?EABDID?H?C@IAACDFI?>@HDH@CFD@GCCFGB?BE@GAD@DG
@>chr21:9849949-9850095-5
ACCACTATGTCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCNCTTTTGTGCTAGCTCCAAGGCTTGGGAGAAACAGAGTGCTCTCCCTT
+
AFB?EGFHEB?EHGDGBC?@IFAIDBHEFHFBHEB@CG)DABH@C@BDIIGC2DHGIBEDBHGF?AGCDHDEE@IHBCC@@EEE9BAB@EFGBIEBCHCB
@>chr21:9849949-9850095-0
CTCATACCANGCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCCTTGG
+
?ECCIHHBH$HE8DEG???AH?GHHGDFIC@??EE?CHHE?CCIAADFE@D@FAIH@AHIHGG?C?F@?HBDG@HGBAGG?DF?BCGEBH?HAEGFHCI@
@>chr21:9849949-9850095-1
CTCATACCACGCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCCTTGG
+
?D@DFGICGI?CB?HG?@F@HICDFCECF?CEEABFGDCGHH@IE@AD?D?CEGB?HB@IIH?H?@BD@EC@FGBDB@F?ACBECICHGDGDFC@DFHGE
@>chr21:9849949-9850095-2
CTCATACCACGCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGANCACTCTGTTTCTCCCAAGCCTTGG
+
FFCB?GFDHCBF?GD@BIAE@GAIAGFHECGA@HDH@G?FBF?I?EDEA@HF@B?A?AID@I?FDB??FIE@I?F5BFDFG?@DI?BEGBE@EADGAIA@
@>chr21:9849949-9850095-3
CTCATACCACGCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAAGGCTTGGGAGAAACAGAGTGCTCTCCCT
+
E?>IGBCDDGCAAIGIGCHBD?BGID?DBA@FDB?1AFHFH?GE@DGAAAGBABBH?D@AADCHDGADBBFGFFG@CCFEHECF@F@@D@@BIC?EFGGD
@>chr21:9849949-9850095-4
CTCATACCACGCAGCTTTTCTGAGTGTCGTTCCTCTTTCCCCATATCTCAGCCCCTTTTGTGCTAGCTCCAAGGCTTGGGAGAAACAGACTGCTCTCCCT
+
FCDAFCDIGAAIHBFAEIFBEAHICIDC8IGFAEIH@@DHG?I?GFIC@CHCH%EAGEEHBHHIHD@B@@HIIAEI@??BIACHHEBBH2BGGG?AGEAD
@>chr21:9849949-9850095-5
CTCATACCACGCAGCTTTTCTGAGTGTCTTTGCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAAGGCTTNGGAGAAACAGAGTGCTCTCCCT
+
FGHDCFCGIEEF@AE?IFFAIEHABCEAAAI'H?@E?ICDBBA?CIBHH?IHFCAACDIF?EBB?FIBHHHHCDD@C!EAAHCHFICFFHGIGGGG?EHH
@>chr21:9849949-9850095-0
GAAGGTCCTCAGCCAGTCTCCCTCTGCAACTCATCTTTCCACTGGGGATCTCTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGGATGGGAG
+
EB?CIBEBA@F@EG@@HIE@I@AEB@EBFFCB@#?BHBEDIDI?@AHHCAC'ADB?BG@CG?BCD@GIFE@FDGEE@HBGAGBB?FCDA?CC$IA.FFDA
@>chr21:9849949-9850095-1
GAAGGTCCTCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTTTGCAATCCAGATTAAGGGAGAGCACTCTGTTTTTCCCAAGCATTGGAG
+
CHGFIGGCF5FA@GCCGAGCGDA?B?D?CIA?ABDCHAAGGBBI@EGGGD?5?GIH@BHAAAHHG@G@B@IHEFCEEC@DECGE<F?GE?DHAC?C@HFF
@>chr21:9849949-9850095-2
GAAGGTCCTCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCATTGGAG
+
F?AAH?B?AFHF?CHDHD@@G@HGGF@DDAHGD?BHAHBB@GAA?A?BCFC@HB@?D@DBBDHB@DBGG@EF?AEEE??HADF?IEHE@H@AHFFAB?CA
@>chr21:9849949-9850095-3
GAAGGTCCTCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAATGCTTGGGAGAAACAGAGTGCTCTCCCTTA
+
BGBEHBFB?EADDDEBIH?BG@FCEFIB?DFDHHCEBDFDAABIAB@GE@C@FF??@?CHCI@AIB@I?B??BIH?GHEHCIHGHEB@D?@C?IFCDACE
@>chr21:9849949-9850095-4
GAAGGTCCTCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAATGCTTGGGAGAAACAGAGTGCTCTCCCTTA
+
BEFFF?HE?CC@?@DEDIGIB@FAECACHCDC?EEE@?@H?BD@CDEC@?AFDGGCBF@FD@GAIC3CIFCE@BCAEGFCIDFA@@DC@HF@??EA?B??
@>chr21:9849949-9850095-5
GAAGGTCCTCAGCTTTTCTGAGTTTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCCCCAATGCTTGGGAGAAACAGAGTGCTCTCCCTTA
+
FGBIEGBIF@BDBIHFDFHDDCD%D@ADDDI@F?IF?HIFAF@DA@CH?EF@BI@H@@IBD?IEC;?AIIAAAC?HHH?ADA@FC@@G$@@GH?I@F@EA
@>chr21:9849949-9850095-0
ACGGCGTACAGCCAGTCTCCCTCTGCGACTCACCTTTCCACTGGGGATCTGTGCAATCGAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCATTGGAGC
+
2HH5IGDFDEFEFEFEFAECDGAD?I*I@GFDAHDFFEBCFIGBFGEAAD@HABHDDC'C@G@@EFHHFCI@BE@G@H@IBGIB?GA?HFCC?BIEH@IH
@>chr21:9849949-9850095-1
GCGGCGTACAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCCTTGGAGC
+
HI@@IDIDHBHF@@AEFF?DBDFGA?GBC@CCIF@GC@HCA@GAHBI@H?GFFHAGAHED@@GG?AHG?ABFGC@?AIF@C?CBIEAEF@F@?CFGAB@I
@>chr21:9849949-9850095-2
GCGGCGTACAGCCAGTCTCCCTCAGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCCTTGGAGC
+
BB?GA?HG?@E@GEFF?BFGGGE1GHIA@DI@FFE@IAADFB@@HI?DGCHBC?DHGHAB?GCBDAGG@?CFF@EGEEHH@BGFDFGE?HH@,ABBACEH
@>chr21:9849949-9850095-3
GCGGCGTACAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAAGACTTGGGAGAAACAGAGTGCTCTCCCTTAA
+
BAABDFGBGAD?CBEHDG@C@BCH@DCC?FCBFE?AFBA@IAIADIAGHGEDBHCCDIBG?IEBBIHGCB3HCDIBFHFFAH@B?H?ADADF?DACICGB
@>chr21:9849949-9850095-4
GCGGCGTACAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAATGCTTGGGAGAAACAGAGTGCTCTCCCTTAA
+
ABI?CHFE@C@!HBGCHBH@AFB?E@GGCD@EDHIHIHFDDAGCAGAGG@DFEC@IAHBI?ECDHC?HE??AFCFA@EG@CGAI@ABFEDDFIHH?H@E?
@>chr21:9849949-9850095-5
GCGGCGTACAGCTTTTCTGAGTGTTTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAATGCTTGGGAGAAACAGAGTGCTCTCCCTTAA
+
HGBGEGAGEECFEB?H?EAAABFA"DF@AIC@EG?IFIEGB@CG@DGHHHG?BBHBHDI@BCGDDFD@H?EIHCB?IHI@EFGC?FE@H?@GHAIF5BAA
@>chr21:9849949-9850095-0
TCAGGCGGTGATCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGATCTGTGCAATCCAGATTAAGGGAGAGCACTCAGTTTCTCCCAAGCATTG
+
HG?C4@E@@*ADA@FB@DGB?I@BD?EHHHHADH@HF?CFECGF?AG@EECCDG??FBI@AAHCF@EADI?IEGBEBAGD?@!@BH?AHB???I?AHBG?
@>chr21:9849949-9850095-1
TCAGCCGGTAGTCAGCCAGTCTCCCTCTGCAACTCACCTTTACACTGGGGATCTGTGCAATCCAGATTAAGGGAGTGCACTCTGTTTCTCCCAAGACTTG
+
?D?@3FC?HI/CGHHBGDGG@@CFB?I?BFIE?FFBDAIHB+@EGADFCGHEF?DGEFFCHE?@E?HHGDGBG@I,ICCEI@?EDI?EHABGEFH>?F?A
@>chr21:9849949-9850095-2
TCAGACGGTACTCAGCCAGTCTCCCTCTGCAACTCACCTTTCCACTGGGGANCTGTGCAATCCAGATTAAGGGAGAGCACTCTGTTTCTCCCAAGCCTTG
+
HIFAHHB?@H6@@A?BFGFDDDAHB@AFDHIBB@AGB&FF@CI?DDEAF?B4CGHD?CGDAIGAHDCIC?H?GH@EAGDBHHCICFBGD@II???DCDFF
@>chr21:9849949-9850095-3
TCAGACTGTAATCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAAGGCTTGGGAGAAACAGAGTGCTCTCCC
+
DGIEBI*FGCB?@BAAA?FBDFDHECHACIFEBIEAH@GBHFIBHBFFDC@CD@F@IDF@IHAC@GCI@@EDEFF@@H?IH@@HCF?FAAF@BH?@DBGA
@>chr21:9849949-9850095-4
TCAGACGGTTATCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAATGATTGGGAGAAACAGAGTGCTCTCCC
+
?BF@ACAII>D?EEGIFAG?FCEBBAFHBEGIHEBDDEDB@GCFCCEDHE?D@FHCBGGEDAHIF@IFF@DG@GE1ADGF@HEGDHHABEEBGBAGBABD
@>chr21:9849949-9850095-5
TCAGACGGTAATCAGCTTTTCTGAGTGTCTTTCCTCTTTCCCCATATCTCAGCCTCTTTTGTGCTAGCTCCAANGCTTGGGAGAAACAGAGTGCTCTCCC
+
AAFIIEECEIBDGDIFAFDDGBADFHEGFAFCEAB@EBB?GHC?AED?GEBIGAGHDADF@B@?FIACFIFIG=GCDCC@DHGCE@4DGBEABIFCDCDF
@>chr21:9850092-9850253-0
ACCACTATGGCTGCAGNCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTGGC
+
EGFEGIIEB%IGBBFC1BCCCFFI@ICIGEF@@BA@GEC?IGCHGHD?DGCBADEIGDCAEF?IBG@BGEBIIBHIBHE?@AGF?HIH?CHGEICIECH?
@>chr21:9850092-9850253-1
ACCACTATGTCTGCAGGCATTTCCCCAGACCTGGGACTTAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTGGC
+
C@@BGGEFCFHEAGHIHFFHBFFBGCEFBEDGGB?CAA.F@?EIAIGEBAGHCEGB?GDDHA?@AH?B@@DEHGHH?IICHGHA?IA1DF?EDABFF@HD
@>chr21:9850092-9850253-2
ACCACTATGTCTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCACTTTTTAATCTGGGCTCATACAAAGTCAATCAATGTTTTGTGCCTGGC
+
DBBG?D?F@C?IBF@A?G?IGAECHEIE@DA?@HHBFFFHAHD@ABADEG@$FDEGDHI@?DH?IFICGHG?GEHAIDFI@HGG1I@GC@?FDDBAAEHI
@>chr21:9850092-9850253-3
ACCACTATGTCTGCTCCCCTGTTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTNCAGTGGCCATCATTGCCAGGCACAAAATAATGA
+
F??EACFCHF@GIAIFCA@?E>ABECAIAFAA?IIEGBDIFD?CBDF?AFC@I@FDDGGDAGBGGB"@DBFID?GIC?DCDFI?EG@ECABEED<AHE?F
@>chr21:9850092-9850253-4
ACCACTATGTCTGCTCCCCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATGA
+
EBDC?DDHI?D@BHBC?F@IHCC?HHBIC@IIH?AHEF?BGHIHEE?HHF?F??IFBB?EDCAHDHBDFDCDBABC@@AHA?D@E@HGGFIDAHHDFIIC
@>chr21:9850092-9850253-5
ACCACTATGTCTGCTCCCCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATGA
+
GICC?FGHBEGBCHGDIICIFDIH@FIEAFA@D?CEDB?F?DHBAB@DIB?IFG?ACAI?GDDGICIG?EICBAHCDAIHCHGGIDCGGBHBFFHDEHE?
@>chr21:9850092-9850253-0
CTCATACCACGCTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTATGTGCCTGG
+
F@IBBEAFBGEGHE?I@C@DEBFBAGCDACG?CHAIAAI?IH?IHGBIC@CDBBH@GDIABFDH?G@GAHAHB?DDBE?D?IHHBEDBDH"BI?FB@IHF
@>chr21:9850092-9850253-1
CTCATACCACGCTGCAGGCATTTCCCCAGACCAGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTGG
+
GAFBFA?AECCBHCII?GBGHHDDBF?HBIBF5E?HEBIABH?GIGBDG@GACHCEBDDHB@AEHF@DDA@I@E?@?IECF;F??ICAIIFAGFAIIGIG
@>chr21:9850092-9850253-2
CTCATACCACGCTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTGG
+
AEGDBBCAFABA@AGEHHIG@DIACABEGCBCGE?CBHHGCIBED?AHB?FHCHG?@GBDBI@AEF@ADGE@DCGACDB?IFGICEBHDEDHB?C1HC?H
@>chr21:9850092-9850253-3
CTCATACCACGCTGCTCCCCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATG
+
D?AGCCEB?G@?ADCHBCB@FFGE?GCB??AFABBHIIH@FCIHIFBHABE?CF?BD@BDHEDIFD@GGIIEGHADFADHCHBDGAFE@FDACEBF@FCC
@>chr21:9850092-9850253-4
CTCATACCACGCTGCTCCGCTGCTCCAGAGCAAGCACTCCAATTCCTAGACCAAGAGTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATG
+
IFDHCCI??EGI?AGEICG?CECH?HEEDBACC??ED??AAHHFHHCEF%EGFHHF9IIHBBGIICDDGFAHEE?@DFCHCAC?AD@?FGI?FIDDE??H
@>chr21:9850092-9850253-5
CTCATACCACGCTGCTCCGCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAATATTAAAGTGTCTGCAGTGGCCATCAGTGCCAGGCACAAAACAATG
+
?FHDCAAGGAEI@?GB@HGGFBBC?IAAIHD?I?ADDHCFBIACIDHAD@I?GC(BFCDFICBIHBHAEGGCDDBBBBB?"D??AC@FEG@B?D?ICEEF
@>chr21:9850092-9850253-0
AAAGGTCCTCTGCAGGCATTTCCCCAGACCTTGNACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCCATCATTGTTTTGTGCCTGGCA
+
=@I@AE?BFIB?DBEIEIBFAEFEEBG@?@A4D%@CA??@FGCBAB@@DIGIHFH?HFFAHAGCA?D;IDGFBBBA?F&IF@B@?FBAABBCBDFBIBI?
@>chr21:9850092-9850253-1
GAAGGTCCTCTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCTTGGCA
+
D@CGBGHECEH?FDFFFH@HGIGH?GI?HFD@DDHHB@EAACF@FH?CABA?FBBGBC@F@?IB?AECE?FB?BDEI@AAHDAFBAAIEHC?FD%BD?HF
@>chr21:9850092-9850253-2
GAAGGTCCTCTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGGGCCTGGCA
+
?AFGH?@?EGDIHG@HGIAAEEEE?F@DCEH?EDEAABFCA@GGDHCACBEEA?CBIHHEIFFDAI@EI?GGDGF@CAB??I?ID?GC?GF)?AF@?GD?
@>chr21:9850092-9850253-3
GAAGNTCCTCTGCTCCGCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATGAT
+
)D@I(D@IEIGGIGCDBADHA?HFBDF?@GE@D?HAI@CBGBFBGG@BABFCGADFHFE@HAAIAHAFHF??CHCCHDDEHIDFADBGAHGHBBIDBC@B
@>chr21:9850092-9850253-4
GAAGGTCCTCTGCTCCGCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCNAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATGAT
+
FGFCI??HGGGAIABE?AE?HB@IAHADHH@@AC@FDAHCHACGIFFBH3BFE?GH@II?@FBB@?IEB@?@FG?GHEEFF@BHFHACAGGEEIIICDBC
@>chr21:9850092-9850253-5
GAAGGTCCTCTGCTCCGCTGCTCCAGAGCAAGCACTCCANATCCTAGCCCATGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATGAT
+
@HHGFFFB?BDBEHBCE@?CABHDEBD?DBEFAIF?EIH8!GHF?GGBGEE.?GEHA?GEGFIAGBFCGGD?E@EG@I?@EEHHCF@IBFDDFH?@@BFD
@>chr21:9850092-9850253-0
GCGGCGTACTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTGGCAA
+
?CBD?DEFCBHF?BBEBF??@GI?ACGCG@CB?BDH?AHF@ECCHD?EFGIB@I@@?GCA?HD?DDBG@HDF?#HDC?CG@AHCI@?IEAAEFD?CDGAH
@>chr21:9850092-9850253-1
GCGGCGTACTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTGGCAA
+
IFBADDCDBBHIHHHD@@AHFAEA@DBB?G?AE?CAAACIH@EDAAEF?AHGFGFI@AGHIGBD@G@HEGAGBCFEFI@?AFHEBBCCC@AB?ICFAG@I
@>chr21:9850092-9850253-2
GCGGCGGACTGCAGGCATTTCCCCAGACCTGGGACTGAGGGAAGTATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTGGCAA
+
GF@BHI>ADHBI@EH?GIDBAGHG?DDDGBHGBHDAID@#A@GB+HG?FFHHEDAEF@EEECBEF@H?IEFAD@GFBHEHIFDBGCDAD@IDCCEBCIBA
@>chr21:9850092-9850253-3
GCGGCGTACTGCTCCCCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAATGATT
+
HIIGDA@I?EIEADDGF@@BDFIHFCIEG@GDCCAEI?@IABAAB?E?A@H@H?BABI5GIIHE!B?FGHEE?IIBAFBCDC?CGIGEHGEGIHIBFFCE
@>chr21:9850092-9850253-4
GCGGCGTACTGCTCCCCTGCTCCAGAGCAAGCANTCCAATTCCTAGCCCAAGATTAAAGTGTCGGCAGTGGCCATCATTGCCAGGCACAAAACAATGATT
+
@BBBGH?DGHFIFDEFFICB?CBEDBABCHGHB-I@EAFEDEEEFEAC?EGDBAFGIIHEFE?:?IAGGB@GDBC@?DA?FAGFGBHICC?DBAG?I?GB
@>chr21:9850092-9850253-5
GCGGGGTACTGCTCCCCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAACGATT
+
FH@A<@A@GDDHGAEA@BAAHCFDAHFBFAB@ADDGEAFA@ED@IH?IFG@E?EAE@@FFDD@HAE@C?B?FHIAHHAH@?I?@CAD?HGI@DF@>??HE
@>chr21:9850092-9850253-0
TCAGACGGTAATCTGCANGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTGTTAATCTGGGCTCATACAAAGTCAATCAGTGTTTTGTGCCTG
+
E?DGBFFCD?GEECFHB'AB?@@E@CEG?FGBID??DGFCHC@I@H@D@HAAGFIH?<?DCGG?I@IDIGGEFDBEABDDE@HIF*1HGI?FHAFG@HBE
@>chr21:9850092-9850253-1
TCAGACAGTAATCTGCAGGCATTTCCCCAGACCTGGGACTGAGAGAAGGATGCCCTTTTTAATCTGGGCTCATACAAAGTCAATCATTGTTTTGTGCCTG
+
B@IFGF;AIEIBHAFHFDBA?FAICHIEEB?@FFEBFDC@B@?BGC@GHB?G???EEAA?ADGG?GBHFFCIAHHEDDDD@GGCIBAC?@CHDA?@?@BB
@>chr21:9850092-9850253-2
TCAGACGGTAATCTGCAGGCATTTCCCCAGATATGGGACTGCGAGAAGGATGCCCTTTTTAATCAGGGCTCATACAAAGTCAATCATTGTTTGGTGCCTG
+
EF?EGEIEC@@?CHF@GCIBBCAEAAE@HAE<3@F@E?HE?7F?GHA@?H?CCEHID?FEDBFF;CICFIEAADE?AE@BEFBFB@IDHIFE>HIEDGGC
@>chr21:9850092-9850253-3
CCAGACGGTAATCAGCTCCCCTGCTCCAGAGCAAGCACTCCAATTCCCAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCCCAAAACAAT
+
-DCBAFEIBDGHD5AIIFIGII@EHIDIGIFDBF?@DEICGACGAEG:GBBACBEG@FAIDAH@?@?@CEAAGA?F@@EDDHICAAIFAI6AEIGC?H?F
@>chr21:9850092-9850253-4
TCAGACGGTAATCTGCTCCGCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAAT
+
BA@CBBIHGCHIBBBAFBFABID?F?AHE??HDIHAAHHGACEGCE?I?BD?FGCAECCEEFIBAC?CHCFCEAIE@GDGEABAHIAC@HABDDIAGIGE
@>chr21:9850092-9850253-5
TCAGACGGTAATCTGCTCCGCTGCTCCAGAGCAAGCACTCCAATTCCTAGCCCAAGATTAAAGTGTCTGCAGTGGCCATCATTGCCAGGCACAAAACAAT
+
G?F?GBFEAEB?CBGCIDFIGB@?E@FHHFEFIAEH@GCCDAI9EBEF@I@I?FCA@FD@DEG?EEABDBI?GEFFDDBHF?DFB@F?GCH@FDBH@BBB
@>chr21:9850250-9850393-0
ACCACTATGTCAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTNCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGTAGGACTGTA
+
B@HIF,CB@ECDFG?IFDFHFIAH?F?G?BAI?HCEH@@DD?@H?A@DIC5G?FFDAIGH@@?AAG?GE@DFBA?GCFHDBF?EDA@BF?CGECCHBE?H
@>chr21:9850250-9850393-1
ACCTCTATGTCAGCCNCCACCGCCAAAATTGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGCAGGACTGTA
+
IHF)FFCGAB?CFBB#C?B?@??F@7??HABDCDC?AHBBBHB?DIHHID?CID?E?EA?IFIIEC?IEBDGECG@@DIH1EB@CIBAI?HEFCBGGEEB
@>chr21:9850250-9850393-2
ACCACTATGTCAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGCAGGACTGTA
+
CBHDFFEIEFA@A@HDACB?I@D?I?HHAIFEBFIG@E@GDFAGCEGDBFAFACA@AEAIEA?@FA@ABEECHIEHDCHE?AGAGFEFFEC@I@BGBHCH
@>chr21:9850250-9850393-3
ACCACTATGTCTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTGCAAGAGGAGAGAGCCTAATTCCAACAC
+
DIFIGFE@GHBBAAI@DF@@CFDIGA@FE?@@?DEDCD?D?G?A@E@BH??C@GFBBGCEHEDADICBC?DDFBGGHGCDAAIBICIDCGIIEDBDIEEA
@>chr21:9850250-9850393-4
ACCACTATGTCTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACCACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACAC
+
BICI@DDGC?HB?@A@GIHIIAAGEFCFEH??HAHAEDIHG@DFAFA@AFCEEGBIBID?FCA:GCEE?EIAB@GHCFIIHA@GEHIFE@E@@BGGA?HG
@>chr21:9850250-9850393-5
ACCACTATGTCTGCAAGTCTCACCATCCTTGAGAAACCTCNGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACAC
+
GGICAIAHICIHG?EFH@EIHFGGCBGBCEGIFD@B@AGF$HF@@HHDGC@EGDHBCG@@CEI@EEC?CH@BAGIBEAFEG@EFBBBIHGHH?BIFB@GE
@>chr21:9850250-9850393-0
CTCATACCACGCAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCCCTAGGAGTAGGTGTTTGAATTAGGCCCTCTCCTCTTGTAGGACTGT
+
G?@E@G?I@FCCI@GFCBH@H@BEHD?GA??GEBAGHHCDGAG@IEGFIE@DEGD$DCIEIAHAEBAHB.IBFG@CHCG"AI?GI?FEIICGBFA?AGGF
@>chr21:9850250-9850393-1
CTCATACCACGCAGCCTCCACCGCCAGAATTGNGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGTAGGACTGT
+
EDEHE@CBCCFHECHAI@IADB@AE@F-E@CH6@EC@D@BCABIHFE?AAFEADAGFCIHAEI?AII@@FHAFD@BA?AFDAG@GBCGE?ICEBIFEG??
@>chr21:9850250-9850393-2
CTCATACCACGCAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGTAGGACTGT
+
H@DII@FAF@FAH?D0EFDG@DCCHGC?GEGGFCCEBI?@EBIIF?GCHDAIAH@DAAHFBBCBBGEBBHBDAAAHIFCA@FCAAHHEEHHDG?FBE?CF
@>chr21:9850250-9850393-3
CTCATACCACGCTGCAAGTCTCACCATNCTTGAGAAACCTCTGCTTTAGGAATTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACA
+
EDDHAIIE??DB@?BF@EHA?GDF?A@<E?IEBHGHGAHACHBCA?DCH@BD"BB?FBGBAHD?@FG@@?EBA?AGADIA?GAAH?C@CDEDEFDADIAF
@>chr21:9850250-9850393-4
CTCATACCACGCTACAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACA
+
E@AGAGCGAAEE@$DCCFDIFH?@FAGGDDBFGB@CA@HHDB@GEB?EBBHEH?GFFHBC??F?H??G@DBBFAEEFHEA?GGEA@EFHFCE?DFF@F@D
@>chr21:9850250-9850393-5
CTCATAACACGCTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACA
+
DCGEA@(HIECC@CIHFFHGAAEAEFBCGG?HFI@EEIC?IA@HA@FA?DADCHCGB?CI?GF?GFCF@HCCHEFABDF?F@H@?IGCEAI?IIG-DHGI
@>chr21:9850250-9850393-0
GAAGGACCTCAGCCTCCACCGCCAGAATGGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGTAGGACTGTAG
+
H?FEC1CF@@D?IC??DGHFDBFAE?@D,EAF?D??EIE@FBFFGBFCFFAEH?@GBA??EAEFDIGFEGECIAC@IBFEIEEGEIBBCFEIF?@?FHFA
@>chr21:9850250-9850393-1
GAAGGTCCTCAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCNCCAGGAGTAAGTGTTGGAATTAGGCTCTCTCCTCTTGTAGGACTGTAG
+
GCADI?IFAHE@?HDEFHCE@@CECIGCFHECIDAHI?EGH?IIHCEF@ID)@EGFA?C@H;FHCAHE?ICCCA@FBHGGAG?HAGHFH@EHDDGIID?A
@>chr21:9850250-9850393-2
GAAGGTCNTCAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGTAGGACTGTTG
+
?DBAGDB-IED@AGCCGGBG@EACBI@F@F@B?I@@B@EDIECBEIFFIAGDEA=FEAHGEFB?HHFGBDFHAAAIBCFHIACCDI?@DFH@DEAGDA3,
@>chr21:9850250-9850393-3
GAAGGTCCTCTGCAAGTCTCACCATNCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACACC
+
HFGCDGDCGHD?BCDB5AH@DHBEH-?HBF@HDHBHBGHABDEBBEHE@BHB?AABECIBB@?GIH?BGBGGGAFFIGCGE?HIAHDHAGEBA@GEGHEB
@>chr21:9850250-9850393-4
GAAGGTCCTCTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGACTAATGCCAACGCC
+
BFIDI@DECCIAHHBB@@?CGB@C?BFADBB@AE?HBBECHECAEBDFE?G?EAEG@FAHGCHAGAHB@CEIHFCGH?EBAA@CF7EBHFF<HICAH)FA
@>chr21:9850250-9850393-5
GAAGGTCCACTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACACC
+
GBBA?I@A)AICIHE?HABDAIDDBBG?HCAE@DBBIFB?I@GDBIDDIFEII@@IAE@HE?DEHGGGBDD?BDCAGBACEG?@H@EIHDIF@!@DIFFD
@>chr21:9850250-9850393-0
GCGACGTACAGCCTCCACCGCCAGAATTGGGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGTAGGACTGTAGT
+
GCI7BEGGBI=ABHA?DI?EIDEAAAFHC)?EDCFCGDEBGC@CD?FG?ECAGHAEHIGDFICCBABCFCHHI@BICEE?FF@EH@DIGG@G@CGCF?GB
@>chr21:9850250-9850393-1
GCGGCGTACAGCCTCCACCGCCAGAATNGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGTTCTCTCCTCTTGTAGGACTGTAGT
+
?IE@HDHB@@GDB@?@FB?EBEA@FHB)IADBCDHIDAAHFCHAH@?ABEGHDCCBG?IAFGADB@CIBA?H@HF&IAHAGGE@FG?DI?IE?BEECIBD
@>chr21:9850250-9850393-2
GCGGCGTACAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGNATTAGGCTCTCTCCTCTTGTAGGACTGTAGT
+
F@FAECBB@H@BEDH@F@EDFCGGFCEDD?FGI?@?HG@G@BBHFHFFICICHAF@CEEA?@DG@B?B$E??GHHCEG@CHDEDDFCD?IBDBH@AIF?B
@>chr21:9850250-9850393-3
GCGGCGTACTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTATTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATGCCAACACCC
+
GA@?A?GIFH?BHBIF@?FEIAGAIGGFDEA@@AIBCAHIAHDC?DAG?HCEG5I?ICACHBAGF@EHDGHHH@AGFIAH,BFCBD@AAC'@HA@@@E?2
@>chr21:9850250-9850393-4
GCGGCGTACTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACACCT
+
IGDEB@DFCEFGCDB?HADCGDDFIEGAEFEG??IHCFII@AHBHDGAHI@I@DAGHICIHHFEG?HF@EDDEDEIIDF@EAHCI@EAGDCFEC?B?HID
@>chr21:9850250-9850393-5
GCGGCGTACTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTACAAGAGGAGAGAGCCTAATTCCAACACCT
+
EI@?D@CFG?BIAGC@FBBHF?H@CFCCAE@EAIF@?@IGBADF@GI?G@EF?IGHHEH@D@DF?AH?H?DCD?HBIGGH@DI@AIIAAFCAFG?AFEI@
@>chr21:9850250-9850393-0
TCAGACGGTAATCAGCCTACACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTCTTGGAATTAGGCTCTCTCCNCTTGCAGGACTG
+
DCECBGCHE?DHEHEFIF#H@DCEFFHAAFDE?FBHGBD@CAFIC@ADHABCDIDDA@FG?@GEGC@3EDEBADA@DIEEIAE@IGG+CCC?AFCH@IE?
@>chr21:9850250-9850393-1
GCAGACGGTAATCAGCCTCCACCGCCAGAATTGAGTGTTGAGGATGGAAAGTGCCCCAGGAGTAGATGTTGGAATTAGGCTCTCTCCTCTTGCAGGACTG
+
#?B@E@@IDG@CDHA?BFG?BBDIFD@HEDBHDHCHFF@H@F3HBFBB@HCF@DCGAIHDHDA?D)CIGBAFDAEDAAIE?BBGA@FBDA?@IHHEC@DF
@>chr21:9850250-9850393-2
TCAGACGGTAATCAGCCTCCACCGCCAGAATTGAGTGTTGAGTATGGAAAGTGCCCCAGGAGTAGGTGTTGGAATTAGGCTCTCTCCTCTTGCAGGACTG
+
I?B?DHBGCI?DHABH?CHCCD@@CD?HD@HHABIBDBDEH@?AAFAAIDFB=C?@I@?HDCABFFHFFE?FADCHAIFHFEAEEFHB????AE?HEABD
@>chr21:9850250-9850393-3
TCAGACGGTAATCTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTGCAAGAGGAGAGAGCCTAATTACAAC
+
EAIFEBBGA@E@FEFF??@DCB@DCG@AECEE?BH@EHHGC?HCAEHGHHFECG@HHID@E?ADHHHG@@@FHB?GID?HIBG@A@FCGEII@HI>GIGG
@>chr21:9850250-9850393-4
TCAGACGGTAATCTGCAAGTNTCACCATCCTTGAGAAACCTNTGCTTTAGGAACTCTCTTCCCACTACAGTCCTGCAAGAGGAGAGAGCCTAATTCCAAC
+
BEFDCHFABABBFD??DBH?$FFI@BBD?CI??@C@B@FIC.BCHA@GAAI?AE@FIEFGCCABIGDHHAIHHGADCCEBDGDG@AFEAHDHBH?H?AAB
@>chr21:9850250-9850393-5
TCAGACGGTAATCTGCAAGTCTCACCATCCTTGAGAAACCTCTGCTTTAGGAACTCTCTTCCCACTACAGTCCTGCAAGAGGAGAGAGCCTAATTCCAAC
+
CCA?@EIDFCDHIEBC@F@EBABGFICBGGHEGCA?@?HCCEAC?DC@GGEFGDCFH?GD?EIBHFFGADIEG@ECIIBAFHCCEAGDECCBI@EAEBDB
@>chr21:9850624-9850711-0
ACCACTATGTCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCCCTGTCCCATTCCTAGTGCACTGCTCAGA
+
DA@AE@HIFABDGEH?IC?BG@A??@A?HCBBFBIF@DEDBBFA?@HIEH@GBCBA@HD@DE@EH@CAFGA?E?BBFCE3C@D@AFH?FGG?AAHF.DBI
@>chr21:9850624-9850711-1
ACCACTATGTCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCCCTGTCCCCTTNCTAGTGCACTGCTGAGA
+
CG@BGGCC@FHCGHHAE@DHHF?EFEIAIE?A@EGCBHEG@FCEG@GCCCAFIFA?G@HI@CCEIHEBDB@AEBAC@AEDFE(HF?EEADFIFDDG?HBD
@>chr21:9850624-9850711-2
ACCACTATGTCTGCTGAAAGGGGCAAACCAAAGCCTGGGAACAGATTTAGCGAGGTAGTCATCTCTTGCCCCCTGTCCCATTCCTAGTGCACTGCTGAGA
+
@?CH@@GIE@EBBFCEGFAEHIIED*CACE??DBAAACA@EIIEEICGAE9IIH?DE?F?F@(DAIAC@CDE?FGIICI(CABC@@A@?FDIA@G@HBAF
@>chr21:9850624-9850711-3
ACCACTATGTCAGCAGTGCACTAGGAAGGGGACAGGGGGCAAGAGATGACTACCTCTCTAAATNTGTTCCCAGGCTTTGGTGTACCCCTTTCAGCAGAGA
+
FIAEGE?@IFCB)GHAHCBGABHICIAGIDE@AEH?BG?B@C?FF?@E@BAG@AGEEHGHII@(GI@I@"EFDCAAE@@DDEE'ADE@@GIFEDDCGAEI
@>chr21:9850624-9850711-4
ACGACTATGTCAGCAGTGCACTAGGAAGGGGACAGGGGGCAAGAGATGACTACCTCTCTAAATCTGTTCCCAGCCTTTGGTGTGCCCCTTTCAGAAGAGA
+
CI"?CAH?BABCBBG@GIH@G?GGDDIGBGGBDA?AF@C@B?BG@AFCGFAADCCA?D?G@CFFCHD??BIED(AHCABCDGIIEHFICC?FHA1C@CA@
@>chr21:9850624-9850711-5
ACCACTTTGTCAGCAGTGCACTACGAAGGGGACAGGGGGCAAGAGATGACTACCTCTCTAAATCTGTTCCCAGACTTTGGTGTGCCCCTTTCAGCAGAGA
+
>@AHG@1ADG@FAGEDIII@@FD,GBAEBAGHEICEDCHFD@FI@DDACFBA??HHE??IGA@IH?GCE?HDF8?GDD@FHBDBEEDFGBIDE?@HC@EG
@>chr21:9850624-9850711-0
CTCATACCACGCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCCCTGTCCCCTTCCTAGTGCACTTCTGAG
+
H?HIFGIG?FDAEAGIHDFBH?GGCIEFGEG@HGCECHBHH@IBDIF@IHCF@GADIADBBIA)?@?AEIE?@DEFI>IGIFHGC?CA@GB@?C%CIDAB
@>chr21:9850624-9850711-1
CTCATACCACGCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTGCTGAG
+
@GCHHDGFGI@DCAADDEDDIAFEEFEGBH?GGA@ICEBD@?FD@HCD??ICCA/?B??AHG@IEC??AIFDHECE?FB?AAGFBFB?DBGIHGHCE@EA
@>chr21:9850624-9850711-2
CTCATACCACGCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGATAGGTAGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTGCTGAG
+
DBHCHE?EGGAFGEFDGC@FHIFDDIH?E?H?F?HDHII?IIEDAIB?DA@@4ABEDE?CCCGBGAAD?IGGDIG@B?HE@D@CC@CGCE?AE@ACHBIG
@>chr21:9850624-9850711-3
CTCATACCACGCAGCAGTGCACTAGGAAGGGGACAGAGGGCAAGAGATGACTACCTGTCTAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTTCAGCAGAG
+
@DI?AFBEDFBBEFEGICHC@EA?A????I@DICIAC@HAAGF?D@CDH???ECCD0@IHB@@?I@GGHEDGE@@BGA??@IFBFEE@AAH?BBDDC?G?
@>chr21:9850624-9850711-4
CTCATAGCACGCAGCAGTGCACTAGGAAGAGGACAGGGCGCAAGAGATGACTACCTCTCTAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTTCAGCAGAG
+
IC@EEF(BDGBIFIIE?HBAB?@GBCCHD2DC??HBEB)FBIEBDGFF?F@G?CHGHFEBCEAGBBCBDGECHEIBFEI??CGGHBGGFGCCHDG@GDGG
@>chr21:9850624-9850711-5
CTCATACCACGCAGCAGTGCACTAGGAAGGGGACAGGGGGCAAGAGATGACTACCTCTCTAAATCTGTTCCCACGCTTTGGTGTGCCCCTTTCAGCAGAG
+
DFABEICHDB?BDDFF@HCFACC@@GIFC?AFDC?BEA?@IGEG@FAIEHADD@C@?FBHGABIH?ICCFE?G*?H@CDAE?@CAB??AIB?F@EBEIIC
@>chr21:9850624-9850711-0
GAAGGCCCTCTGCTGAAAGGGGCACACTAAAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTGCTGAGAT
+
FHDIA%G?H?HHACBED?G@IGDDAEA3IAE?DH@@HBIB@BAIEIGECCFEGFAEDI@HGFHFI@AFBAFGIGB?IC@DCGDIHA?FB@DC@FIHIF?I
@>chr21:9850624-9850711-1
GAAGGTCCTCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTTCTGAGAT
+
@ABDA@@C@G??GECAD?A+FIHBIFCG?AEBIDIIFGGDIGBFFGCIDDDICDBIFHIHCACFB@EFCFGHABAABBCAAGA?GFCEDHGD-DHDDBDB
@>chr21:9850624-9850711-2
GAAGGTCCTCTGCTGAAAGGGGCACACCACAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTGCTGAGAT
+
EIDB?I@HAHGBIHG?D?BHFCAHHEGBG,I?GEBDCDG?HC@IHEBBEGE?HFCBGEB?@?GIG@E?G?IDCGDDDI?G?FHFAB@?BEGHGBBDI?HE
@>chr21:9850624-9850711-3
GAAGGTCCTCAGCTGTGCACTAGGAAGGGGACAGAGGGCGAGAGATGACTACCTCTCTAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTNCANCAGAGAT
+
ADC?FGHIEAIA?3DGAEIGGF?IC?I@ECAB?HHCEII%AFDDCGAEEGGCAGAFEC?DHADFBB??FA??EEGEEGAECDGGCDHA@!?F;BB@IDD?
@>chr21:9850624-9850711-4
CAAGGTCCTCAGCAGTGCACTAGGAAGGGGACAGAGGGCAAGACATGACTACCTCTATAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTTCAGCAGAGAT
+
0DEHEIG?DIDCH?FEI?BDIFE?@?CGHFHBBCD@A@EGAEF2AAEBII?CECCI0H?CF@GFD@IEFB@A?@BHE@GCGDB@?G@HBACIBFGF@?FB
@>chr21:9850624-9850711-5
GAAGGTCCTCAGCAGTGCACTAGGAAGGGGACAGAGGGCAAGAGATGACTACCGCTCNAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTTCANCAGAGAT
+
HFA?EG@BC@A?D?BCIFCCCEFBGE@CCGBFGB?@C@DGHI?HDD?BCI?BF(B?D.EBCHCIBBIGFCB@?EHI+CBCICFDG?H?FFAD>?EID@EG
@>chr21:9850624-9850711-0
GCGGCGTACTGCTGAAANGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTAGTCCTCTCTTGCCCCCTGTCCCCTTCCTAGTGCACTGCTGAGATC
+
?AADEB?FH??GCC@EC(HDD?EIHEBIEDDD@BA?@DD??BDIIBI@FI@E@DFIA?5BH?ICGCCCEEIDAH?@DCBEHHBHAEAG??@IAA?BIGDD
@>chr21:9850624-9850711-1
GCGGCGTACTGCTGTAAGGGGCACACCAAAGCCTGGGAACAGATTTAGNGAGGTAGTCATCTCTTGNCCTCTGTCCCCTTCCTAGTGCACTGCTGAAATC
+
DDCIDIDG?DHGH@6CACIFCADFCIB?IBFIFACDEHG@H????GDF0HAGIEBFAE?C?EGGED3CCI@@CFHGADFECBCBCBEDIGEAHACF9HEF
@>chr21:9850624-9850711-2
GCGGCGTACAGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTAGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTGCTGAGATC
+
C?BA?EECD.EDDDCDB?ED?IDE?IHI@IIBEGIAEFGE@?ADF@@F?CFCDB@AD?C?<EBHEEI??DC@C?EFHGDFGHHCGAF@CBICEHFGHGEH
@>chr21:9850624-9850711-3
GAGGCGTACAGCAGTGCACTAGGAAGGGGACAGAGGNCAAGAGATGACTACCTCTCTAAATCTGTTCCCAGGCTTTGGTGGGCCCCTTTCAGCAGAGATC
+
H%?BCCH?E?DIFG??DGDDD@GBBI?AD@DCFBEA;G?DCACCIBCH@IBIIDE@BDDACIIA?CDG@?@F@GEIGIEC0CEEEBHAGB?DDFCAGIB?
@>chr21:9850624-9850711-4
GCGGCGTACAGCAGTGCACTAGGAAGGGGACAGGGGGCAAGAGATGACTACCTCTCTAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTTNAGCAGAGATC
+
B@??EFCGH?AAFFFACCIGEDAEIFI@AIBFE?ECFFDEB?AF?ABG??ACEBGHHEEHAA@EHDF@EIAHEEII@CG@HGEDBA@BD4HEG?BGHCHA
@>chr21:9850624-9850711-5
GGGGCGTACAGCAGTGCACTAGGCAGGGGACAGGGGGAAAGAGATGACTACCTCTCTAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTTCAGCAGAGATC
+
?;AF@GHBG3@HCHDDGGE?A@@%GGCHIHEIEG?CI*AC@IH?G@IBE?@GFB@BAEEFB@F@CCCGIGBIEADDGAAEH@G@GIFGHFF??A@DEIB@
@>chr21:9850624-9850711-0
TCAGACGGTAATCTGCTGAAAGGGGCACACCAAAGCCTGGAAACAGATTTAGAGAGGTAGTCATCTCTTGCCCCCTGTCCCCTTCCTAGTGCACTGCTGA
+
AEED@BHBBHAE?HHE?AI?IB?HFGE?@??GEI@AIDCA8IIAHHAFE?FEGEAF?@ICGDCE@FHD;I@@BBFFHDHH?HGHEGEC@AII?A?CGEB?
@>chr21:9850624-9850711-1
TCAGACGGTAATCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTGGAGAGGTAGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTGCTGA
+
@?GGGHBGD@GGGAFFFAIFEHGFFI?DFEGFC?G?ED?EIB?C@@D?IG$IBGBFGEDBEABICAIEBGGGDB?IFAGCCBGDIHDAFBCEEECFIE@@
@>chr21:9850624-9850711-2
TCAGACGGTAATCTGCTGAAAGGGGCACACCAAAGCCTGGGAACAGATTTAGAGAGGTNGTCATCTCTTGCCCTCTGTCCCCTTCCTAGTGCACTGCTGA
+
D@FCD@DFGFBCIGD@IH@DHDE@EAGHHDBIFHDCCBH@GAC@@DE@F@GD?GDHFE6BIEDHDHIBCD?BHGCCH@@IDDBDACE?HGCI?AHHE?AG
@>chr21:9850624-9850711-3
TCAGACGGTAATCAGCAGTGCACTAGGAAGGGGACAGAGGGCAAGAGATGACTACCTCTCTAAATCTGTTCCCAGGCTTTGGTGTGCCCCTTTAAGCAGA
+
?FCBHDC@GIE?DDG?FB?AAEFBAGDCHH@DABFEA@?BGCHF?GAEAAIIC@FEDC@BHDE?EIADH?CHIDEGD@GHBGHAACE8A@CHB-DIDHGF
@>chr21:9850624-9850711-4
TCAGACGGTAATCAGCAGTGCACTAGGAAGGGGACAGGGGGCAAGAGATGACTACCTCTCTAAATCTGTTCCCNGGCTTTGGTGTGCCCCTTTCAGCANA
+
ECECBFEC@G?EGFEBCIECG?GCA@ECCEHHGBDEGEGDD@AA@ABAF@@AFIGF$E@HGADBHFHBE?CE?:AAGDHFCBFB?H@I@BHBA@EH@F#H
@>chr21:9850624-9850711-5
TCAGACGGTAATCAGCAGTGCACTAGGAAGGGGACAGGGGGCAAGAGATGACTACCTCTCTAAATCTGTTCCGAGGCTTTCGTGTGCCCCTTTCAGCAGA
+
IBGI@B@HABHD@FHE??ICCBEEIIBCEG?GFD?HGFDGC?@IC?E?GFIGGDIB@HHDFGBFGHBA?@EC2FF@FHE?>?I@ED@EC?EDEEC@ABB@
@>chr21:9850708-9850768-0
ACCACTATGTCTGCAGACCCAGCAGTGGACATCCTGTTGGGGCCCAAGGAACGTAGGCTGAAAGAGGCTGAGATCGTAAGAGCGAAAAAAAAAAAAAAAA
+
@D@ICHACGC@GEDCE@EB?BF?GDI?DDCCHFCGCACAH?EBAAAIDDA@EFI%IFIDGIBB@?AECEFIC@CAG7?DD@CEHAD@G@@CIEDEE??GB
@>chr21:9850708-9850768-1
ACCACTATGTCTGCAGACCCAGCAGTGGTCATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGATAAAAAAAAAAAAAA
+
EEH@IGH?EIEFH@G?IBC@?B@AH?ABIDFCBHBFGEDGDHCB?GHBFFF?IE@CGB?E@FCICEGBFGIAFDIBD?IHDDBIF:BGAECEBCH@@B?@
@>chr21:9850708-9850768-2
ACCACTATGTCTGCAGACCAAGCAGTGGTCATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
C@FIEAFI?G@CBGCHABE7@C?GF?DEIGAHDFDIIAEDACEFE?IIAGGFAHDGHCFDCHG@AHDFIEBEADBBAAFHEACDC@AAHDEFCA?EHCAD
@>chr21:9850708-9850768-3
ACCACTATGTCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGACCACTTCTGGGTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
I?HDGI@H@DCCADDADCHGIFAHBIB?ACIIHGGG@ID@DI?E?@GDGC?BFD?AF-F??IA@GDEEDFEEGDBE@A?@HC?IF@DEABA?EDIE@AEG
@>chr21:9850708-9850768-4
ACCACTATGTCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
CE@?B@BBEBCICACFBFI>HEFGDDECA?ADAIAEECBGCFG?E@IEADAABH@I@@BEDIFF@DFDBEDECAIFHCIC@GIEHDC?GDE@??DGIIBF
@>chr21:9850708-9850768-5
ACCACTATGTCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
A@@?AIIII@EHABGABDEFEBCGABGE@B?C@GGBHCHFEGDFF?ICIA?IGCAHC?F@@AGGHGDD@C@CGDEFDAIBHEGB?CGHHEBAGIAI@ECF
@>chr21:9850708-9850768-0
CTCATACCACGCTGCAGACCCAGCAGTGGACATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
EE@HBCC@?C?DGCBBG@IB@G?B@A@IFFGBIH?EEHDGIFB@H@GBH?FHACHADHDD@GIAFD?F@FIEDAFDBD@?@HD?AIABHE?C@AAAIBE?
@>chr21:9850708-9850768-1
CTCATACCACGCTGCAGACCCAGCAGTGGACATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
A@E@AFFAGACHBGA?B@?GCA*ECGEBG??HIG?E?DEAEGDABIDIA?FIEEGE@DCFFDC?A@AHCGDGEIAGDCFFD?CG@@I@H@I?A?A?IBAI
@>chr21:9850708-9850768-2
CTCATACCACGCTGCAGACCCAGCAGTGGACATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
C?EFCFB?@EF?F?HIFE@EC@CGAIDGFABBIDBG@FEAAIGEH@GI??DF@HIIDHEAB?E??FAFAEAACBG?IHG@HAAGHIC@?DGFCHI?HGGE
@>chr21:9850708-9850768-3
CTCATATCACGCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
HCD?@G)AAFEFFFFGAC@A@GAGCGG@GICGAF?FGCF?DAHFA?AIB@IDH?CDADHEDBG@F?DFBHAICHDD@BCEA?F?GFD?DEADEADCHBHB
@>chr21:9850708-9850768-4
CTCATACCGCGCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
CE@EBFFF5B@/AG@C@?EGHCHGFHIICAAACEGCIEDI?IGGIAAH@GCHCBHIDBHCGEAF>EI?DFDCE@@IEG@/A@CGFIC)EDCIC@?AEHCD
@>chr21:9850708-9850768-5
CTCATACCACGCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCTGCAGAGTTCGGAAGAGCGAAAAAAAAAAAAAAA
+
BDHII?GF@CFF?IEIH?E?E?ICFFEABHAIB%D@?GDAFCIAB@ACFDBBH?E?H@@HB??GBFE@CCAID"C?HCGDIF?FHBCBGEEGF@FEHGDD
@>chr21:9850708-9850768-0
GAAGGTCCTCTGCAGACCCAACAGTGGACCTCCTGTTGAGGCCCAAGGAACGTGGGCTGAAAGAGGCTGACATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
DF?BGGGHD@HHAB@F?DFI;HHGBBIBA&HAEAB?DG0EBCAD@@G@EDGI?CFFDF@HAHCDDCBIIA2BFG@DHIIEA@FBCFECICIG?D@GBI@F
@>chr21:9850708-9850768-1
GAAGGTCCTCTGCAGACCCAGCAGTGGTCATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAGAAAAAAGAAAA
+
HBGACBBBDIDFAGE@HGBFBFAEDB@D?CE@IGGID@F@DCHAGE?AI?FGHHAFHC@G@@GIBICB@BIFECC??BABGCI@?HAI/BE?EHB:BHAD
@>chr21:9850708-9850768-2
GAAGGTCCTCTGCAGACCCAGCAGTGGTCATCCTGTTGGGGCCCAAGGAACATGGGCTGAAAGAGGCTGAGATCGGAAGAGCGCAAAAAAAAAAAAAGAA
+
?FGADIIDHD?CHAGIDIFECE???AABHCC@GCFGABC@BFA?FCBHA?I;HGGGIIHB?E?EDC@AEIE@C@GCBCHFDCH.DCCFIAFICGIHI&CH
@>chr21:9850708-9850768-3
GAAGGTCCTCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGACCACTGCTGGGTGTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
EI?ADA?BBCGFB?AEG?BGHECHIB@BBIBECA?GCD@BCHAHA?AA@I@C@DFCA@FIC@E.@C@?CH?B@EAABGADCIDFDE?HG@A@EFGEHGAB
@>chr21:9850708-9850768-4
GAAGGTCCTCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGNCCACTGCTGGGTCTGCAGAGACCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
C?EH@E??GGGDGEAAGBGIF@FAHAEBEICA@?GIC@DBFFCDIADEI@7@@GGHHA???GG??EI?IID?&DFIEICIGAHGBF@D?EEIDBFHBDFI
@>chr21:9850708-9850768-5
GAAGGTCCTCAGGCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTTGGTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
?B@CCA@EDCFE<IG?E??D@HGGB@AGGAIFIBAED@GCAEAHD@BHGDHABDCCE?C#EDIEFGHG@IIB?EHFDHEDEFCBABDCDDG?D?HC?GIG
@>chr21:9850708-9850768-0
GCGGCGTACTGCAGACCCAGCAGTGGACATACTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
D@@IHHGG@GEBHGGABHBHFDBBHH@EIE&EHC?GDEH?EHA@BGCIDCIA?I@?DBFFAI?B@F?@ADBHBIGADAF@DFG??@GBGFBCHBD?DCIC
@>chr21:9850708-9850768-1
GCGGCGTACTGCAGACCCAGCAGTGGACATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGACGAGCGAAAAAAAAAAAAAAAAAA
+
DDGA@HAGH@HHI?AA?EHGIEAHGEHEGE"CBBBEAACI?FABFBIBEFECHIADEIBCCEHFD@FD?IB@AFFH6IB@IDDGGAC@EEGCE??GFB@I
@>chr21:9850708-9850768-2
GCGGCGTACTGCAGACCCAGCAGTGGACATCCTGTTGGGGCCCAACGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
?IDHHDIAGFA?HHEFAAAEFEF@CCGGA?DCEI@GAA?IHDFAG;ACHHBGGCCHI@@GGD@H@GHFDBDIIBIHAAEFBBD?@HD@FGE??HAHDF?C
@>chr21:9850708-9850768-3
GCGGCGTACAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
HGFGHC??C?BBB@@G?EBIDHD@HFHFDA@CGCE@DDBBHFGDDDC?HEB?D@?G??ICGGE@@F@FC??CECGIHGAIH?EDF@@B@AGFGGH?C@C?
@>chr21:9850708-9850768-4
GCGGCGTACAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
IGAFCAAAH?ADGCBAFBIHEDEECEGGC?GCBF@DB?AE?EB?@DC@GGFFIEEBB?FIEI@A?ID@DBHCFCADDAIFCAIF@BHHDBBAEG@I>?BG
@>chr21:9850708-9850768-5
GCGGCGTACAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
@HDCCH@BDG?HHGICBF@EEAD?GAEICBI@AEIF@IFCE@BEBBIED@AFIHFCDCE@DHA-GB?BEBID@EA@GI?EHDAFAIAABBEACCGHCH?@
@>chr21:9850708-9850768-0
TCAGACGGTAATCTGAAGACCCAGCAGTGGACATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
B@IBDE@@DDBGBEB8HI@HIH@HCED?GGEIEGF?EF?DCEGHFF?@HIBD@IEHEH?B?DI?ADEBGCDCGCBDCGFGHFI@HDHDGHGDF@BCCGED
@>chr21:9850708-9850768-1
TCAGACGGTAATCTTCAGACCCAGCAGTGGACATCCTGTTGGGGCCCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
GDAGH@@@DGCCAG.?DABCAAIEG@F@ACG?G?DGAEBGDB@D@IB@HFEA?HA@GDFIEBIB@@EA@IEFGC?DCCG?C@C?DI@?B?FIAE?@FD@B
@>chr21:9850708-9850768-2
TCAGACGGTAATCTGCAGACCCAGCAGTGGACATCCTGTGGGGGCTCAAGGAACGTGGGCTGAAAGAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
AE@F@CBDBF??B@B?CIA@CHH?DDCEHIIEHD?BAEA;IF?ID/CDCBHEHB@?CI@FAD?FIDIB?HGFGCBG@EBEGIHDG?IGD@EBGH@GDFBG
@>chr21:9850708-9850768-3
TCAGACGGTAATCAGCCTCTTTCAGCCCACGTTCCTTGGGCCCCAACAGGATGTCCACTGCTGGGTCTGCAGAGATCGGAAGAGCNAAANAAAAAAAAAA
+
BCFFBDIIG@GDDB@@CIH@A@?CIHCCDAI?DIBACEGHIA@?DCBD?HA@@??EHHDCHFCFHFFGG@IEE@EGEABBFIGEF+I?F0IB?IGGECAA
@>chr21:9850708-9850768-4
TCAGACGGTAATCAGCCTCTTTCAGCCCACGTTCCTTNGGCCCCAACAGGATGACCACTGCTGGGTCTGCAGAGATCGGAAGAGCGAAAAAAGAAAAGAA
+
I@DDCGIFHDBHGE?FBEEGBBHA@@AFBCIE@DHIF3DBIBCCBGFEGFC@F!IHI?BCCBIHF?HGHAH?HBCBHID?FHBEEIHDDHBH-GIGA&GB
@>chr21:9850708-9850768-5
TCAGACGGTAATCAGCCTCTTTCAGCCCACGTTCCATGGGCCACAACAGGATGTCCACTGCTGGGTCTGCAGAGATCGGGAGAGCGAAAAAAAAAAAAAA
+
FF?EGC?A?BDD?BGIBF@HBCCCH@CCHC?C:IE0AAECAD8DGAD??CEBH?EI@HDDA@@GDC@DGI@ICFIE?E?)BGDABAAGI@DBIGCEFAFD
@>chr21:9850786-9850894-0
ACCACTATGTCAGCTCTGCCCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTGGNCACTTTGTCACTTCTGTACCTGTCGAGGACAAGTACACA
+
IDHEC@@GA?FH?BF?IDADD@IBBI@E?GDHHHDD?HAG@?CBG?FEGGGG?AFH@A6E4B@DBI@E?HH?EFA@HIFBBHGDG@CBDBECFCDE@AEF
@>chr21:9850786-9850894-1
ACCACTATGTCAGCTCTGCCCCTGCTGAAGAGTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTACCTGTCGAGGACAAGTACACA
+
BBD?IBAFECED?@I@BD?ICEAHG@BBGCG;DDDIEIIGEGFCGAEE@GGHIB?BHAG@?GID@IGE?DBCFG@C@EIEH@@IE@B@DFFDD?@AH@E?
@>chr21:9850786-9850894-2
ACCACTATGTCAGCTCTGCCCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTACCTGTCGACGTCAAGTACACA
+
?GAGG@IGBFBABHIHE@DH@GDDHHCECB?IEEBIFAFDA@IBEADIH@BCHIID@@FECEEA?F?@DB??I?G@BCCGBHGFFDE5F9HGGGDFCA@B
@>chr21:9850786-9850894-3
ACCACTATGTCTCCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGGCAGGTACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTACCAGTGTGTACTAGTCT
+
FFEC@AEDDBHG8CGE@E?AFBF.D@EAFIG?A@A?@?AF@@?F/AIABDEA@FD?ICDDF?AGCGHHBBDFFF@GFIFFAI(D?C@DCHIDCEI?G@@F
@>chr21:9850786-9850894-4
ACCACTATGTCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGGTACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGTCT
+
IHGH?D@IA@H@GDCFCE?D@GCD?HGCAIGCCF?G?E?BCAGFCDAF?EIG?H@GED@GGE.GAAFB@GEGBHGHI?I?DDCEHCIIHGBFIEI?IA@F
@>chr21:9850786-9850894-5
ACCACTATGTCTGCAGNGTCTTCTCCTCTGTGTACTTGTCCTCGACAGGTACAGAAGTGACAAAGTGCCAAAAGCGCCCTTTCCCAGTGTGTACTAGTCT
+
D@BIHBE@GDDAF@IC$?@BAGF@@DEHDEHFGFEICHBEGFF?HEG@FHGAHEEBEI@BIF?GB?BG?IAEDEGF@GIA4FBCDGIDG?ACFCADA?@G
@>chr21:9850786-9850894-0
CTCATACCACGCAGCTCTGCCCCTGCTGCAGACTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTACCTGTCGAGGACAAGTACAA
+
AICECF@CAB?EG@CEDCIEIDEIFBEF;I?D?AGAGI??EDFAFIIGAAFFI@DIHBACB@GFFHH>AGEB?CHHECB?FFEDDGFEGIEEIFCDEBD-
@>chr21:9850786-9850894-1
CTCATACCACGCAGCTCTGCCCCTGCTGAAGACTAGTCCACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTACCTGTCGAGGACAAGTACAC
+
E?HIABIBCDDBHABFI?AFFG@D@CIA@ABBA@HFI&ABIACFB@GDD??HI?FADBEEG@@@ICDACCG@DFC?EFAGDBHDCIADGHDDH?HHCAA?
@>chr21:9850786-9850894-2
CTCATACCACGCAGCTCGGCCCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTTGGCAATTTGTCACTGCTGTACCTGTCGAGGACAAGTACAC
+
IGE@ICAHECHF@AACC-F@IBHIDECAFA@FAGI@I@GB?IHD?CIFFE@@AB?GDFC@EBGH>DAAAE?@@E#EC@F@GFAFIAABBB?HBAFAH@EF
@>chr21:9850786-9850894-3
CTCATACCACGCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGANAGATACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGGN
+
AD@BCGFAIBGEHEEB?EC?BAEEFDDH@F?BAGHCIDGF@E@?HA:B@,@AIGEIFIFBEB?I?EHBFGDAB@I@CCA?DCEDH?AAFBBFDHHDBB2(
@>chr21:9850786-9850894-4
CTCATACCACGCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGGTACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGTC
+
ED@EBDEI?H@IHIHAA@HIAEGHFC?HB?=HGAEAHBHBI@CCH@@GDG?EEDCDBHEEAADBHCIBIACCDD+FGEFBEBAFH?AEACI?@?IC@FA?
@>chr21:9850786-9850894-5
CTCATACCACGCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGGTACAGAAGTGACAAAGTGCCAAAAGCGCCCTCTCCCAGTGTGTACTAGTC
+
EF@@I;E@EF??@CHC@IEF?D@ECEEB@F@BE@AACH@EBF@IBCFAIDF@@HCCECDIHCBGEHCHIFFEICEAF?I?G7ACBAH?FEBHI@HA?GEH
@>chr21:9850786-9850894-0
GAAGGTCCTCAGCTCTGCCCCTGCTGAAGACTAGTACAAACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTATNTGTCGAGGACAAGTACACAG
+
FFBIHHAC?IHCHBEFACBGHCEHBGH?HB?B?HFIII8GBHD?EDBGBAGE?FCBDH??FDFIHG@HAFFDF?@IH@E!FGACDHGGAGHBCEDI?I?A
@>chr21:9850786-9850894-1
GAAGGTCCTCAGCTCTGCCCCTGCTGAAGACTTGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTCTATCTGTCGAGGACAAGTACACAG
+
AEBHIFCHH@BBCBFBHCIEBCIGHEGAEBIA'??CCBIAG?I@EAFGDA@HHEGFDHCCDIEDB@@GDH?ADE?1GGACGB?@?HF?BFGH@F@F/A@C
@>chr21:9850786-9850894-2
GAAGGTCCTCATATCNGCCCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTATCTGTCGAGGACAAGTACACAG
+
@ACHCFBC@DI<>DI>HGHH@?DAH?GECFB@AGH51AED@FFAEBFH?FBF@HIEBFCF?FH?@HBIFIFHCB@HDEBGAICFGHA@BFH@??D?GC@D
@>chr21:9850786-9850894-3
GAAGGTCCTCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGATACAGAAGTGACAAAGTGCAAAAAGCGCCCTGTCCCAGTGTGTACTAGTCTT
+
CDG?@?F?IFD@???FI@CIEEGD@F@E@HH?D@@G?FHCBI@GIEBBIBADAIDEIBEIBGA?C@G;GADHHF@HACBBHDAC@EGCECGCHABFIEF?
@>chr21:9850786-9850894-4
GAAGGTCCTCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGATACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGTCTT
+
D@I?EHC?GHABHAF@FE@IE@@@GICEAGIC@CB@IHBFIFBHF@DHA@CDEGHC?GEG?EE@H@?FCGB@FAEBGGIBCE?D?DH@?A@GBDI@HGD@
@>chr21:9850786-9850894-5
GAAGGTCCTCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGATACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGTCTT
+
BBHI?C@GIFC@GGGGACG?E?IBAEDE@D@EGACI@ECEHFF@HEC?BEHIGCCE?@GCHGI@EC@?A?@HI?AC?B@@FAA?DCFIHHBAAC@II?A?
@>chr21:9850786-9850894-0
GCGGCGTACAGCTCTGCCCCGGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTATCTCTCGAGGACAAGTACACAGA
+
?A@F@EC@FIHGD?FC?@G?-?DIHIHEIGIEG@HFC@CIIGIDIGCBEGFFB@0GFF?IGAEHBICC?@FH@AFFHBFG8GABCB@?GHB@?IHEHDGE
@>chr21:9850786-9850894-1
GCGGCGTACAGCTCTGCCCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTATCTGTCGAGGACAAGTACACAGA
+
HCIA?I?C@II?@??CGBBFD@EE@??BGGH@EHBCG@FEHCCDAFCAFHBH?BC?@IHF@@@ADGDHEIFBDFDDAEBDGAHCF@IIEGDBGEDB@BAB
@>chr21:9850786-9850894-2
GCGGCGTACAGCTCTGCGCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTNTGGCACTTTGTTACTTCTGTATCTGTCGAGGACAAGTACACAGA
+
A?BEI?@GFEDCECFAE9ICFBCD?G?CAII@EHF@CHBHGIEIGH?HIIE@G@@'CIEDDHCGD@G!BDEEHADGG@@B?EGG?FDBIIE@C?@BAD?F
@>chr21:9850786-9850894-3
GCGGCGTACTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGATACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGTCTTC
+
ACBEAI?DD??CFBE@BHF?AFHH@@GAACHEABIEBBID?I@EFDH@HFH?HBG?BG@EDBI@?FDGG@IH@?EA@HH@GFBBC?C?BIIIGA?BF?FE
@>chr21:9850786-9850894-4
GCGGCGTACTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGATACAGAAGTGACAAAGTGCGAAAAGCGCCCTGTCCCAGTGTGTACTAGTCTTC
+
?BFIH?ACFIH?AGGD@@?AIBFGGB@BIGIGHA?F@EHEIAHCIC@HEFHIA?G?HFGAEIGIAA,@DBBAAHGCBFFC??IICFIH?G?HIIB?HHDE
@>chr21:9850786-9850894-5
GCGGCGTACTGCAGGGTCTTCTCCTCCGTGTACTTGTCCTCGATAGATACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGTCTTC
+
CEACHCHDGDGE@IIBA@GGFGHFBH)@IF@?GGB@IDI?GG?$AEGGIA@IBAFGGCDEICHED??@IEHF?F@DEEHAFDFFFH@HAHI?FDIIAG@C
@>chr21:9850786-9850894-0
TCAGACGGTAATCAGCTCTGCCCCTGCTGAANACTATTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTGCCTGTCGAGGACAAGTACA
+
AH?H?@@BECICBCDCHCGA@@?FBACICAH6HFE?*DHACHDD2C?@GCI?F@BB@HFICFI@AFD?BEDBGGHD@BDF"AG?IHDADICCBHAHC@IC
@>chr21:9850786-9850894-1
TCAGACGGTAATCAGCTCTGCCCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACATCTGTACCTGTCGAGGACAAGTACA
+
ABH?FGD?I?FDBHBDIA?F@EA@DDG@?HDDCFC@@A@HD@GFBBHG?@?IG?IBICI@B?FCICHHHAIFCG>@CBA@IDAHA@HF?@A@GGD@DD?B
@>chr21:9850786-9850894-2
TCAGGCGGTAATCAGCTCTGCCCCTGCTGAAGACTAGTACACACTGGGACAGGGCGCTTTTGGCACTTTGTCACTTCTGTACCTGTCGAGGACAAGTACA
+
?B?B2HDBBIBDIH?C@HEDB@FAGHB@?GG??H@HI?DCFDIB@HE@DDEFD@HDFEHCBBB?DHG?DIBDI@CIBCAAE,DHCIBIBHDBG?C??GC@
@>chr21:9850786-9850894-3
TCAGACGGTAATATGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGGTACAGAAGTGACAAACTGCCAACGGCGCCCTGTCCCAGTGTGTACTAGT
+
HE@G?AFHEAII1G@ACHIHB@GB@E@HGHCCIFIDADHGFDHBCCHGID?FIBGBG?BAIHBHFG;??GF@H::HFCIDB??HDEGDCAABF?IIAD@@
@>chr21:9850786-9850894-4
TCAGACGGTAATCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGGTACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTAGTAGT
+
CIH@@FFHCABAGB@E?BCH?EECBAHGFHHDDGBGBH?I@GEFG@BA?CCE?EF@B?DCAEEHGEHEIGGH@?@CG?DGECDAHICH?DFGFCB#@GCG
@>chr21:9850786-9850894-5
TCAGACGGTAATCTGCAGGGTCTTCTCCTCTGTGTACTTGTCCTCGACAGGTACAGAAGTGACAAAGTGCCAAAAGCGCCCTGTCCCAGTGTGTACTAGT
+
A@CFD?GHCAAI@AFDGAII?EBG???GG?BGF?FGAAIG@CFB@BE?CEBCDAD?BECEA?HGGH@AEFFEAD?G??FDG?A?DCF?AAABIFHEIID?
@>chr21:9854637-9854734-0
ACCACTATGTCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCACGCAT
+
C??IHCA?@AIDICFAIFBCD?FCCCB@HFF@BBDFE?H?E&@HIBDAHGEDIFEDHHGIC?GEDCI@ED?IF?@BFECEAIICFIHBAAIGFEAAFDHI
@>chr21:9854637-9854734-1
ACCACTATGTCTGCTCTGGCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCACGCAT
+
FCCEHEHDEFCGD?A@BH4CFAGA@IHICG@DBAEGFCIADFHI?DAIEBFGCIAG?CEHIEBHE?AFH@AEDCF?DHBACAIHA@GIDGGEAHBEGEF@
@>chr21:9854637-9854734-2
ACCACTATGTCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCTGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCACGCAT
+
EB?FEFHBHABBFHC@FGFFBH?@GIGIDHCEEG@FCE?HHF?BBBC@CCE@AE%?H?HDIEEH?GG@H?BFA@FI?IAFIHHDIH??ABFE@GGD@DCD
@>chr21:9854637-9854734-3
ACCACTATGTCTGCTCCATGCGTGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAATCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGAC
+
BIB@GE@IE?;CI@BDF@B@CD?CB?HAHEICBF?AAGG@AAHEBCACBFB@IBBF7CEICFEDF?FICGEBIBHBA@FDE?DHHFA@DD@FI?@AGGF@
@>chr21:9854637-9854734-4
ACCACTATGTCTGCTCCATGCGTGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGAC
+
EGFDCI?FD@D@D?@ICG@IAA@DAHDIFA?CFD@C?@FBEFIIB@FIHC@AEG:@C?FFGBBBGBFDHHCFHIH@EBFB@DDADCBIAEFEEGDECEAB
@>chr21:9854637-9854734-5
ACCACTATNTCTGCTCCATGCGTGATGTTTCCTGCACGAGCTTCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGAC
+
@E@GDABA+E@III@GAGAIIIABIGEAC?DEDBIHH3DIGI@?BEFBEBHHBDGI???@B?GEIEHI?EAHA@CHHIGAHEEHAIFFDE?C??EG?FHI
@>chr21:9854637-9854734-0
CTCATACCACGCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACGCCGNAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCACGCA
+
H@CEEGHAC@GEIHCBEAEI?CAIFEADDHGC?FBEBAICEE?A@CDICCAIA+GHG<C@GGA?FFDHCDGD??GBDHGHAIABFHHHD?EE@DBEE?FI
@>chr21:9854637-9854734-1
CTCATACCANGCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCANTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTCGTGCAGGAAACATCATGCA
+
?CHID>F@D+CDE?IICDIDBGDGHD?FAH@HAHHEI?ABAIIEE??D2CEFCHAHFDI?BCA?AABECBBI?A@EEADI2BFBI@D?FB@ADBB?FE?B
@>chr21:9854637-9854734-2
CTCATACCACGCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCATGCA
+
CAH?BGIAHEBFAEFDIF???HBDG@ED@@@@EIEBAEGIHC#?DECBCHEFEBAGHFBA@CBHEFIIHHHEFBI?G@C@GGHIDHCHBDGCADIDIH?B
@>chr21:9854637-9854734-3
CTCATACCACGCTGCTCCATGCATGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGGGGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGA
+
@IGFHHEHEDDBADABBC@IGC?C?DCGIF@EFGDFCAEHAHHADA?IGHC?F?IBEHDIDEBF?9?@HEAGEBDCIEG?A??DG?IFDHCEE?CEHH?D
@>chr21:9854637-9854734-4
CTCGTACCACGCTGCTCCATGCGTGATGTTTCCTGCACAAACTTCCGTTAGAGGGTAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGA
+
GHF0HIFFGCAG?BHDEC?CGEHIAHBC@?BB@E@DFICA'BID?C7GHAB@?D@9DEA?GD?CHH?DHDCIIEE?CIB@GCAH?FDFBEEG@BD?GHCD
@>chr21:9854637-9854734-5
CTCATACCACGCTGCTCCCTGCGTGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGCGGGTGA
+
BEBBEEFHDFA@HICE?H.IIAF?FEH?@CABCGIDI?@BEA@HIEHGH?CEFDGDAIDEDBHC@@?AEBEDCD?BEH?GGD?E?IC?AGCFF&FGIICF
@>chr21:9854637-9854734-0
GAAGGTCCTCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCATGCATG
+
BEBI@FGI@?HGDAAC@HG?IAFFH?EHDIGGD?ACBF@DCIDA@AC?GBHHCH@E@BG@FAIAD?BFF??I?CBGIA@FBFBFABDH?IHDBGGC@CDE
@>chr21:9854637-9854734-1
GAAGGTCCTCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGACGCTTCCCTCAAAAGGAAGCTTGTGCAGGAAACACCATGCATG
+
HIFH@CBGCDBFBACDHAF@FI?I?DGBBGIED@DCCBBBBEBACBEF@E@AGEF?F/DEEFB@D?C2DI??DI?DBEE?AGE@HAE?CD?&?EBACDF?
@>chr21:9854637-9854734-2
GAAGGTCCTCTGCTCTGTCATCCCCAACAGCATGGACCTCACTGCTGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATTATGCATG
+
CHCGIADBBAHFIG?@AH@G=C@ECIFH@DD@EFBEAHBCDBD@?0@DD?GAHFGAFFHGFDHGIB?D@AHFE@?AIBFACBAI?HHDBDED9@?AAIHC
@>chr21:9854637-9854734-3
GAAGGTCCTCTGCTCCATGCATGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGACA
+
CFCCCI?EAF?AEAGGE@EFEHDAG@GGDIED??HAHAFF@E@@?@EAE?DIG??BCBGIFC?A@CABE@IBFEF@@?GCEEDCBBBFHBC@I@@H?D@B
@>chr21:9854637-9854734-4
GAAGGTCCTCTGCTCCATGCATGATGTTTCCTGCACAAGCTGCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGACA
+
HBI@H?ECD@@FAB@G@HIDC'AEGGFCIAF?FAAHFA@AD/@FAGF?HHGE@@DCHGEABIFGBAFDBFDCF?A?GFGBFB@B?BH?I?HGGCEEA@CH
@>chr21:9854637-9854734-5
GAAGGTCCTCTGCTCCACGCNTGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGTAGTCACTGCAGTGAGGTCCATGCTGTTGGGGNTGACA
+
?CF?EC@@GEECDI?C?0HB2BIIFIHCCAA@?EGA?ADBFEAIB@ADE?FHCEDHIGHAE?)IBD9?HAFFIF?CF?DEHDAF@CE?H@FFEC$HFHGG
@>chr21:9854637-9854734-0
GCGGCGTNCTGCTCTGTCACCCCCAGCAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCACGCATGG
+
FC?ED@B'?FIAC@G@B@FCECEBC2CBF@I?A?@@AE?@CCCBHBBHCC?C?HFCFGADADH??BGB@AH@BBBGFD@DCDB@HFI?BBH@ADGFGECH
@>chr21:9854637-9854734-1
GCGGCGTACTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGAAACATCACGCATGG
+
ABCDIFIBCAFCE@GGC@??@DHIAI?IGHB@F@HBIGGFCIGFDCIGDC?HBGCGCHEBBDBFDBHIBCEDFAG@EDCIFIAIIFBACAEDHCDHEF?D
@>chr21:9854637-9854734-2
GCGGCGTACTGCTCTGTCACCCCCAAGAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTAAAAAGGAAGCTTGTGCAGGAATCATCACGCATGG
+
IGDIHCAFF@CIAGCFGH??EADCBG4FAGIFIIFG@@F?AIHHICDFHFAACAIE?C@IC@AGE"2CDCBEA?BG?ADGCBIHEEH&D?CH@@IGHGI@
@>chr21:9854637-9854734-3
GCGGCGTACTGCTCCATGCGTGATGTTTCCTGCACAAGCTTCCTTTTGAGGGAAGCTTCCGGAGCGACTGCAGTGAGGTCCATGCTGTTGGGGGTGACAG
+
B?CHHH@BFDC@EGEBB@CAHDAG?EIGDBDHIEE@EACDGF??F@!EGI?DIHIAFH?F?HEB+@BFB@BGDFIDHAACCGE@ABICACI?ECH@BHEI
@>chr21:9854637-9854734-4
GCGGCGTAGTGCTCCATGCGTGCTGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTGACAG
+
AIBDCCGE5DBEHIG?FIIC@I$BG?BDDAEGE?I@DABHAFFDGGHGIHFA?DFED@@@GFHAC(CG?A@HGGAADGFGH?GA@A?HID?ADGEF@B?@
@>chr21:9854637-9854734-5
GCGGCGTACTGCTCCATGCGTGGTGTTTCCTGCACAAGCTTCCTTTATAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCGATGCTGTTGGGGGTGACAG
+
DBICBE@IEAECIFI@GHA@CF#;CGG@CGE@E?CHECGEHCI@CCF>@C@DHDB?FAG?BAFCCF@CIAGGII?AAA@A)IC?GCGCCAHDIACIGB@F
@>chr21:9854637-9854734-0
TCAGACGGTAATCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTGCAGGATACATCACGC
+
C@@H@EGBAEDBGG?AHAG@AHH?@B?GIBFEDBEAE?B@@EEHGHHA3HIA?@HDCBG@FACGHCEGCDF?BC@ACGA@IGBF@HFADF!CBEACFD@F
@>chr21:9854637-9854734-1
TCAGACGGTAATCTGCTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGAAGCTTGTCCAGGAAACATCACGC
+
ID@CHH@DA@BIB?BIFIFI?EEBDAEFFBEG@A@IBE@IBCCF@FGIHHE?@@CAC@EICECBIG?G?EIHH?AGADIIBCCI3H?HG?GIB?G?EGID
@>chr21:9854637-9854734-2
TCAGNCGGTAATCTACTCTGTCACCCCCAACAGCATGGACCTCACTGCAGTCACTCCGGAAGCTTCCCTCTAAAGGATGCTTGTGCAGGAAACATCACGC
+
AA?B7?AA?H?D@A;?CD?GF@D@DGIFGFACCGADCCCCH/GHB@GAFGDEIIGEHABABAEDD@FFCCGGC?CGH#FBFI@HHF@GIFI?E??I@FEG
@>chr21:9854637-9854734-3
TCAGACGGTAATCTGCTCCATGCGTGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTG
+
HHAHIHGDDAI?DAF@DAG?@GBCI?CFEHBC@I@DAA@CCABDAE@?F?C?AHBECBI@@@EDECGDF?CHCDDFCBEGEAAICGCCAHB@BC?@@GIB
@>chr21:9854637-9854734-4
TCAGACGGTAATCTGCTCCATGCGTGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCNGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTG
+
DBF@EHA?H@FH@ICBFHGE@?IC@@@IGIE@ACE@DB@FI?EHDBAI@EEGGBDF@F@A?BHA1GG?CG?HDI@?GHBEDE?GADGH?BFIB@D?HHFF
@>chr21:9854637-9854734-5
TCAGACGGTAATCTGCTCCATGCGTGATGTTTCCTGCACAAGCTTCCTTTAGAGGGAAGCTTCCGGAGTGACTGCAGTGAGGTCCATGCTGTTGGGGGTT
+
DEFAF@BICIHHEC@AHDAFGBIGADDHFGGC?@BGFIDGHFCIFAHBABGGD?DG?EDAHICBF@?BB?AIG@AEDCHCACDFDCCCBHGB@FI?BAF!
@>chr21:9854731-9854865-0
ACCACTATGTCAGCATGGGGACAGGGGCTGGCCAGCTGGTCAGGTCTCACACTCCTGACACTCAGACTCCAAGATACTCCTCTGTCCCCACCCAGGNCAA
+
DEH?@@DAFAA?EHC@?FC?HAIIH@BAGDH?FCAGF?IHIIEACHCFBD@?EEBGCE@CBBBB?GCFBCC;I?BDDCDCDECBF?@IE?HHDAAG0IC8
@>chr21:9854731-9854865-1
ACCACTATGTCAGCATGGGGACAGGGGCTGGCCAGCTGGTCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGCCAG
+
FCGDH?DGBCGGFBICDH@EFFFFGGHB@GIEBHEHH@D@H@HICIB?BABEA?I.@BCI@EEGH?FFCDCBEHIFGB?G?D@@IECD?C@IICCC7B?E
@>chr21:9854731-9854865-2
ACCACTATGTCAGCATGGGGACAGGGGCTGGCCAGCTGGTCAGGTCTCACACTCCTGACTCTCAGACCCCACGATACTCCTCTGTCCCCACCCAGGGCAG
+
AEIIF@ICDCB?EDC?IGIH!IBAAAHFGCBG@F@CDEBHGIBI@IHHB@IAABBADB@-IAAECFF+EDF?D??CFBI@?HBACCBH@HIBHFEBDDB@
@>chr21:9854731-9854865-3
ACCACTATGTCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTCAG
+
BFCIAEG@HIGADBIDA?@?IICIBHGDGHBIDEID?I@DHFFGBAIFD@?BCCBHAI?CIIB@FFG@DH?A?G?IBCFCD@CIHE?A@GEBCIBBEHCH
@>chr21:9854731-9854865-4
ACCACTATGTCAGCATTTGCTGGACCTGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTCGG
+
FI@C@BHC@IFEBBHDHB@EEADD?/B?GAA?EA@B?C@AAICE?@??H?CIBCDHBCEH@@EBBCDABD@HEFDEFBDC?DCFIHEDIIBGBGIFBE&G
@>chr21:9854731-9854865-5
ACCACTATGTCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTCAG
+
IE@B@EADGABFHGFDDBGFA@FGEHEDCAAHCFI?CAFEGFCHDG?AHC?GB?D??FGADBF@@BEBGACIGGEGC?CC?EFEBBHG@BHAIHGGIECI
@>chr21:9854731-9854865-0
CTCATACCACGCAGCATGGGGACAGGGGCTGGCCAGCTGGTCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGCA
+
CHB?HEEHAE%@CHG@IFBBED@BHDEEBF?IAE?EEFHI@EEBBDHCIEFB?GDHII@IDDCCG?FGADFBHH@DGBDHG@CHGBHGAI@I@IF@ABHG
@>chr21:9854731-9854865-1
CTCATACCACGCNGCATGGGGACAGGGGCTGGCCAGCTGGGCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGCA
+
FGFGC?AFEFEE2HAEGEFGCE@IEHEDBDBB@FFGF?FBDEICE@B@HGGC?HCAGEFD?IBBG?HHAFIFDIACIA?FIGCGHGFAEEIIHAFDED@F
@>chr21:9854731-9854865-2
CTCATACCACGCAGCATGGGGACAGGGGCTGGCCAGCTGGGCAGGTCTAACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGCA
+
AEECAHBBIBHECEHH@DADE?@D?@HGF@@BGIF@AGIDEEIDH?DC"EBGFD@FEEFIFC??CGBDEIECF/H?HGI@AIAF?ABDEAA?CDHAC?HF
@>chr21:9854731-9854865-3
CTCATACCACGCAGCATTTGCTGGACGTGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGGGTATCGTGGAGTCTGAGTGTCA
+
BCI@GAG?IB@B?BD?HFIDB@HIEH#IEG@GHFB@DHC?CCGCEFBHBC?B@GE@CBI@GFEFIDBAE@FACID@?1@BAAB?FBGDAHHIDAFD?A?@
@>chr21:9854731-9854865-4
CTCATACCACGCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGNCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCNTGGAGTCTGAGTGTCA
+
@CDGFACCFGAFC?@B?G?DBCIFE?DHGAFF?F@CHF@@@FEA?A?>ECG@EDBBHI?GEFCCC@EHIBBD?FG@E?EFDHH;GBAACDCBFHHAAD?B
@>chr21:9854731-9854865-5
CTCATACCACGCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTCA
+
FGBCHGIA?HIBECHH??GFH@@BCHIH?EHGADHDEICE?@DCDIHBABDAHFBCHDFEFAFEICGBIGBFADEHBEFGBB@E@HI??@BEEAA@FE@E
@>chr21:9854731-9854865-0
GAAGGTCCTCAGCATGGGGACAGGGGCTGGCCACCTGGTCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGCAGA
+
EE@DFAAFBHEI@B??IIBF@IIHG?DGHD@AB<@@EIGDHGD???GIIBDGDGAEDAEHCGFDGHHD??FAFCAGIFCGE@EGFEICA?HC?EI?CBHD
@>chr21:9854731-9854865-1
GAAGGTCCTCAGCATGGGGACAGGGGCTGGCCAGCTGGGCAGGTCTCACACTCCTGACACTCAGACTCCTCGATACTCCTCTGTCCCCACCCAGGGCAGA
+
?HIDHIHEGF?F?EGDE?B?@HGHAFABH?A?B?IFBBFB?FE@A?A?@E?DIGF@ID?BCI?FFIAGG%D?IDI?DA@G@BI?@?A?DAAGBHDDHIFE
@>chr21:9854731-9854865-2
GAAGGTCCTCAGCATGGGGACAGGGGCTGGCCAGCTGGGCAGATCTNACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGCAGA
+
BAICHB?BC?GC?FDBEDAEHDIBHDD@?EIEBA@HI@BG@C$H?@!HIGEAIIDGHHE??ACH@?AFEDGIFACIDBAGFCBBD@AIGBHCF??FA@@G
@>chr21:9854731-9854865-3
GAAGGTCCTCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGANGAGTATCGTGGAGTCTGAGTGTCAGG
+
AABC?@BEBFABCDA@EI?EGCDCDHDIFGBFC3@B@ID@CCADDDIIAG?@DACC@CG?AHDD@EDCF?DGI)BAGH@@CBCDEHGICHEGIB@?B?CF
@>chr21:9854731-9854865-4
GAAGGTCCTCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCTTGGAGTCTGAGTGTCAGG
+
@BDGEFCC@CHEAF?GDBC@G@@G@AHE?DH?HG?C?DECGBBDDGA@CGCFIID@DIBEBBB@HGC?@DAFEDCADACGD/BGAGBCDGAIIEDAGHH?
@>chr21:9854731-9854865-5
GAAGGTCCTCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTCAGG
+
ABDFCGAIDBGEHGAACGC?DCA?EDBGBEGDECHHIH?EAC@GE?AF@@DEAEI?GE@@BDCEE@C@D,DBBECHF?AD?@FFCGBHFGHGBHAGDEI@
@>chr21:9854731-9854865-0
GCGGCGTACAGCATGGGGACAGGGGCTGGCCAGCTGGTCAGGTTTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCGAGGGCAGAT
+
G@AEBB?HA@CFEGAHB@FIBEHB?FDH@@FECI@FGDBGEH@6@F?FHGHCHDG@?F?DCCHECCGEAICFHFBCGBD?BGEFFBC@EH3CH@FDEFDC
@>chr21:9854731-9854865-1
GCGGCGTACAGCATGGGGACAGGGGCAGGCCAGCTAGTCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGCAGAT
+
BIGGFDHAGB@IFGF?C?BCHDFCDD#@IIAACF?:DHBF@EIH@EBAF@B?H?AE?CAI@AGAGG@HAFHII?D@DHAEDDDD@FA??DHICGBCBBGF
@>chr21:9854731-9854865-2
GCGGCGTACAGCATGGGGACAGGGGCTGGCCCGCTGGTCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTNTGTCCCCACCCAGGGCAGAT
+
GGEAD?GDCBI??IDCACHFADGIEAB@HHC8GBB??GAEFE??CFAFEDCIAEDHE@CD@DBEC@CCIBDEH@BFFAG#DFEFFE?D??A?HE@CGFDD
@>chr21:9854731-9854865-3
GCGGCGTACAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTCAGGA
+
E@A@@HIC@HEBDIFDFAID@AGIBIH?AG@GF?IBH0@F?BIBI@BFA??ECC@?@IIICDAEEDAIAGAFGHHADIAIDA?DFAFDCFBGCC@@DI?B
@>chr21:9854731-9854865-4
GCGGCGTACAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTCAGGA
+
GB?IFGBFHCGGF?@CFCHCABI??EEEB?HF@IHCHCD@HHGCI?C@DEFAHBGAEE@BFDIGD:GAAIFDEIDDH@AG@BAD?GH@ICIFB?GGIHFH
@>chr21:9854731-9854865-5
GCGGCGTACAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTNTCAGGA
+
G0EF?CB@I?DI?BFA@EEA@FFDHEFGEA?ACIFIE<?@CE?BGFCIBGDDCHFCAB?EDDEBEECEACHEB??BAIBIFBFI?IC@G?BGE)(@@CCG
@>chr21:9854731-9854865-0
TCAGACGGTAATCAGCATGGGGACAGGGGCTGGCCAGCTGGTCAGGTCTCACACTCCTGAAACTCAGACTCCACAATAGTCCTCTGTCCCCACCCAGGGC
+
CI?C@DHICCGAG@@CGD@?HE?HDHCAADDFBGGH?A@?CACCACFBAI@HGGGAFIBE0F@BF@D@CDDAGI:CE@*AFCD@H@D@@GEAGECEFFEC
@>chr21:9854731-9854865-1
TCAGACGGTAATCAGCATGGGGACAGGGGCTGGCCAGCTGGGCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGC
+
FBBCHCD@H@@?DCG@DCADFC?@B?GBCADEADHDI@DH?HA@IIAHGDBDCIE??GCAEDEGHHH@F?@G@EDIGIFDEEHHFFBC$DF@CEGG@EEG
@>chr21:9854731-9854865-2
TCAGACGGTAATCAGCATGGGGACAGGGGCTGGCCAGCTGGCCAGGTCTCACACTCCTGACACTCAGACTCCACGATACTCCTCTGTCCCCACCCAGGGC
+
?@B@GCHFFE@@?DHBBACCGIBF??C@ACIACGI?FIGAI4GH?EHBBEGHBGC?GEFGICIFCGCCEE@GCHHCECA@H?IGHEHD.CB@IHGC@E@B
@>chr21:9854731-9854865-3
TCAGACCGTAATCAGCATTAGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTCAGTGTC
+
EBHAAC6BE@EGIIIACIG=BHECBFGCEBCABIED@HFCB?A@DIFF@??HEEIEGGIC@F@GBI@CE?AEE?BBHACBEI@GIIGGCABIF$A@BFC@
@>chr21:9854731-9854865-4
TCAGACGGTAATCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAGTATCGTGGAGTCTGAGTGTC
+
HECGIIGAAA@CCIIG?BFDGCGBAD?CHCFBEEDDCE@HDBBCCAFFGAGCD?F?IEIIEHCF?BBGID?EGACIE@G@IB!?HECIFDBI?DAGHBHG
@>chr21:9854731-9854865-5
TCAGACGNTAATCAGCATTTGCTGGACATGAGGGGGGAAAGTTTTAGGGCAGGGATCTGCCCTGGGTGGGGACAGAGGAATATCGTGGAGTCTGAGTTTC
+
CAC?HGF!@FCFC?GED@GHFEEII@@GEIBCC@GI?A@?IIBAEAHCEHDGDHCDCHAGABHCHCDDB@IDCDHDGBE0A@HCDDEH?E@BFD?GD=FD
@>chr21:9860539-9860632-0
ACCACTATGTCTGCTGATATATAAGTTAACACGAAGGCCGAGGAGTTGTGGNTCAATTTATAGTTTAACAATAGGGATAGCACTTATGTTTTAATACGAG
+
BD?GDGG@I@AAIBGC?FCEEEDG'IEIB:@HD?EFFHDGI?D?GDIHICG5GHE?@CCIC?BDH@EFEFCEE.CCIIEBE@D?DHA@HBIBCIAAGBAE
@>chr21:9860539-9860632-1
ACCACTATGTCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCAATGTATAGTTTAACAATTTGGATAGCACTTATGTTTTAATACGAG
+
AIIBFCC@EGFBGDHEFBE?@HGABHGHEHGGCFBCFBHHBBGGEBIHDFHIHEC@?'@CEFGID@ACADBC:?@FGGCGIGBI@?HG@GHCEGE@EDCF
@>chr21:9860539-9860632-2
ACCACTATGTCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACAAG
+
@DA@?HIGCCG?EGHFDBFD?IAIB?DHG@EABDE?CIHCFG?@CGFDIACAEIA@E?DCH?CGE@BDI@FIFFH@GE@IFBABE?G??ACAIAEGB1AC
@>chr21:9860539-9860632-3
ACCACTATGTCTACTCGTATTAAAGCATAAGTGCTATCCATATTGTTAGACTATAAATTGAACCTTAACTCCTCGGCCTTCGTCTTAATTTATATATCAG
+
BDE@CAAF@?HH:DEIDHDHCBFE%FIAEFADFIID@FCC@@BBGGID;DBBHECFIFGAEDFE9EA@BF?D@A@BDB@CHDBC?HEBDHHHDIHD?IBA
@>chr21:9860539-9860632-4
ACCACTATGTCTGCTCGTATTAAAACATAAGTGCTATCCATATTGTTANACTATAAATTGAACCACAACTCNTCGGCTTTCGTCTTAATTTATATATCAG
+
IGBBACBGDF?EHIFHEIIFCCAFEFBDEFBGFAABIGIEBCID??IH>DHFB@IGHFGDHHACBHFHIII7CH@BC3ECFCGEIHAC@FECGADIEEI@
@>chr21:9860539-9860632-5
ACCACTATGTCGGCTCGTATTAAAACATACGTGCTATCCATATTGTTAAACTATAAATTGAACCACAACTCCTCGGCCTTCGTCTTAATTTATATATCAG
+
DI@GGICI?C?#FD?@IFHDACEIEC@E@8FEA?AHDDCEHCDCIAD?EFBIBIHF?BFDGCIH?DH?BBCGEGFE@@EEBIC@DBIB@G@EFGEDGF@?
@>chr21:9860539-9860632-0
CTAATACCACGCTGCTGATAGATAAATTAAGACGAAGGCCGAGGAGTGGTGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACGA
+
?D>BB@BGBICBEB@IBAA@<HBABAFDICIIFHBD?IEIBHDBEAD2EHHF??CACAICGACA?AIDA?DIFEIA@GC?GEBDF?IGI@ECAI?GDA@B
@>chr21:9860539-9860632-1
CTCATACCACGCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACGA
+
@CEEAHA@HC@?DI?GECG@GC@BAECDIEEGDFAIIFC?CDAGAEAECDBFCDEAA?HI?B?BFDE?DDHGDCBDH@GCEE?IBABFHCDC@FG?A?DE
@>chr21:9860539-9860632-2
CTCATACCACGCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCAATTTAAAGTTTAACAATATGGATAGCACTTATGTTTTAATACGA
+
HDCFADBFB@CGFEIHGAB@IIHBBBHIB@EIHEACHH@EIFAA@D@GD@@BCEHDCCFBA4IABEAA@HIHB@FEEFBBEEB@HFIGAIIE?BAGDCEH
@>chr21:9860539-9860632-3
CTCATACCACGCTGCTCGTATTAAAACATAAGTGCTATCCATATTGTTAGACTATAAATTGAACCATAACTCCTCGGCCTTCGTCTTAATTTATATATCA
+
G?EEBHCCDAIHAE@EBIICBIEE?#AG??AFHHIC?IC?CIEBCGHCE/@GFBEADGGHEDHCAHICBHBFGGAFEHHA@FA@G?GGGCGE?GDBEDEA
@>chr21:9860539-9860632-4
CTCATACCACGCTGCTCGTATTAAAACATAAGTGCTAGCCATATTGTTAAAATATAAATTGAACCACAACTCCTCGGCCTTCGTCTTAATTCATATATCA
+
AEBI@?HDBA??I?FGFIEB@@A@FFEBHIHDAHDGG"CDDGCEFH@ABED(GGAGHGDF@?FD?B?IFH@CHHADDBBBD@BIFGEDDAH1IGACD?H?
@>chr21:9860539-9860632-5
CTCATACCACGCTGCTCGTATTAAAACATAAGTGCNATCCATATTGTTAAACTATAAATTGAACCACAACTCCTCGGCCTTCGTCTTAATTTATATATCA
+
@GDBA@DHGEHA?E@G@ECGC@DAICAFG@H?F?H-GGCIHI@D@BEC?F@BADCGEFBDDBFG@IBBGIICHABGBDBBE?BECBCG?IFCIBFFG@HA
@>chr21:9860539-9860632-0
GAAGGTCCTCTGCAGATATATAAATTAAGACGAAGGCCGAGGAGTTGTGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACGAGC
+
F?BDCBBA?@I?I$CHA@@FA@BG@HGGHIFHDFD@C?<DBABDDABCBBBGDBEDBGGHDFHI?HIHHAG@IBFBBIBHCHHIHIBEB@FI@HE?CA?G
@>chr21:9860539-9860632-1
GAAGGTCCTCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATAGGAGC
+
GA@DCGAIAGGAFIBBHGH?CFI@E?FHECBIH?ACB?IHCGBIAEFB?DC@@@BA?DFHDGFFDHIEIDA@ICIIEDG?@HB??BDBFI?@B@G$@CHH
@>chr21:9860539-9860632-2
GAAGGTCCTCTGCTGATATATAAATTAAGACGAAGGNCGAGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACGAGC
+
FHIG@HFHAFCEF@D?B?BIE@GDG@A@D?ECDDIB4AIEH@?DCADABGIEBFIFCFCHEIIAHBE?C?BC?CBEEF@GAEDECDCEFB@I(CFECCEB
@>chr21:9860539-9860632-3
GAAGGTCCTCTGCTCGTATTAAAACATAAGTGCTATCCATATTGTTAAACTATAAATTGAACCATAACTCCTCGGCCTTCGTCTTAATTTATATATCAGC
+
FBECEI@@F@DG???GHIAFAHHHCBGDGCFF?I@DFDACEFCIEHAGG@EC?BG@BC@IC@@GHI?GBB@FFGG@BIBAFDAGDABBFHFEBHGBE?EB
@>chr21:9860539-9860632-4
GAAGATCCTCTGCTCGTATTAAAACATANGTGCTATCCATATTGTAAAACTATAAATTGAACCACAACTCCTAGGCCTTCGTCTTAATTTATATATCAGC
+
@BBD%BHFIC@HIBFHEA@C@IDA?H@D9CCBDD@GFBFBADEI@$?F?DD?@G??EDFB?DF@DEEH@CI@<?A?HHAHA@CIAFAE@FDGEHBIGIGI
@>chr21:9860539-9860632-5
GAAGGTCCTCTGCTCGGATTAAAACATAAGTGCTATCCATATTGTTAAACTATAAATTGAACCACAACTCCTCGGCCTTCGTCTTAATTTATATATCTGC
+
DF?DFFBDC@A?DC@B1BGBDCA?GDHICDB?I@H?BAHA@GHCGIGHBAGGEGB??GCABIBBA@AHEBCGF??GFIEFIAIBHC?H?F?AIHC@C"FI
@>chr21:9860539-9860632-0
GCGGCGGACTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTGTGGTTCAATTTATAGTTTAACAATATGGATAGCACTTAAGTTTTAATACGAGCA
+
IEGD@I2DDBBFI?FDDGGBIGIFDIEF@FFI@DEGHCG@@GCDB?CACEHAAI?FCHDDEBA?HBII@FDBCFFDGEEGGAGF8CHA?@HGE"BCGFI@
@>chr21:9860539-9860632-1
GCGGCGTACTGCTGATATATAAATTAAGACGAAGGCCGTGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCAATTATGTTTTTATACGAGCA
+
FAGECBGC6BBDCI@BFCHBHGBAEFBBGIF@IB@GFC&@HHDAFBD@AEACDBBBHGCFHHHFDBBGIBBFI@DFCIDF1ABEH?D@?C!GBDBIIBAE
@>chr21:9860539-9860632-2
GCGGCGTACTGCTGATATATNAATTAAGACGAAGGCGGAGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACGAGCA
+
CEBIFF?HIC?EF?@GA?@H!@ID@EBH@??AFH@@>B@?I@@F?ADGHIEH?AHBBGCCGIFCA?BGBEEC@CDACDBEIC?DDF?GHFFB??IG@F?C
@>chr21:9860539-9860632-3
GCGGCGTACTGCTAGTATTAAAACATAAGTGCTATCCAGATTGTTAAACTATAAATTGAACCATAACTCCTCGGCCTACGTCTTAATTTATATATCAGCA
+
GAG@EEIF?IGDI=GIHHBGHBFFCHG@??AFAEEHFH&DFHDHBCF@DBCGCCHDFBFBG@ABFBFE?I?GH?HHB$DB@@FIADC?F?CAIBBD@BBE
@>chr21:9860539-9860632-4
GCTGCGTACTGCTCGTATTAAAACATAAGTGCTATCCATATTGTTAAACTATAAATTGAACCACAACTCCTCGGCCTTCGTGTTAATTTATATATCAGCA
+
DH$GCCGDEI??HF@F?C@AICHIC@BBD?HGFHCGF@BGEGGDFEHB?E(BBHGH@C?DFBA?DDDF?H?IIGEHBEIAI6AAIDGD?CCDEIB?@HIC
@>chr21:9860539-9860632-5
GCGGCGTACTGCTCGTATTAATACATAAGTGCTATCCATATTGTTAAACTATTAATTGAGCCACAACTCCTCGGCCTTCGTCTTAATTTATATCTCAGCA
+
AEB?CEF@BIG?IH@@?B@DB;ABBGH?EFFIG?C?@@IHBGDFA@@DF@@@2BHGIAE0BD?B?DHG?BECG@GF?A?AAB@F?AIBA@?CB3AD??GE
@>chr21:9860539-9860632-0
TCAGACGGTAATCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACG
+
H@FGIH?GDC@G?IHHDBCCFFD@BHCGHECFCCI@BDED??EEIFAHHEFCGDACIAIHECEAB?FIGEHFC@EAIGEHCDDDEC@C?IEEBGDHHECI
@>chr21:9860539-9860632-1
TCAGACGGTAATCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCAATTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACG
+
?C?FFDEFHI?AGFHIHBEI@GEE@A?HE@ACHEFGHAAIHIGEE@BGFEEDFHIHGEHE?BCIICFGAFCHDCIAAHGC@ICDAHEA?CHEEHDFBCD@
@>chr21:9860539-9860632-2
TCAGACGGTAATCTGCTGATATATAAATTAAGACGAAGGCCGAGGAGTTATGGTTCATTTTATAGTTTAACAATATGGATAGCACTTATGTTTTAATACG
+
HHDGDBEDCE@?ECH@DGG@D?GCFB@A?FHCDIEIA@?I?FF?@@@CCI@IGA@FA(HCGEHCDEFDE@?GBDHDD@@BAG?GCIIC@HEGCDBI?FHC
@>chr21:9860539-9860632-3
TCAGACGGTAATCTGCTCGTATTAAAACATAAGTGCTATCCATATTGTTAAACTATAAATTGAACCATAACTCCTCGGCCTTCGTCTTAATTTATATATC
+
?FFGDDBHAECHIEB@ACEEHBIHICC?E?CHA?ECG@EIFFDGEBFGBEDGDCFBGGHHGGFCHG?GAFAFCBG@E?@ABBG@?@IICCH@IIEIHDHI
@>chr21:9860539-9860632-4
TCAGACGGTAATCTGCTCGTATTAAAACATAAGTGCTATCCATATTGTTAAACTATAAATTGAACCATNACTCCTCGGCCTTCGTCTTAATTTATATATC
+
BE?HII@@FCFF@EHEBHEHEI@BAFIH@EIAHAABFBGICFDEA?FBAHHFHHDFCIEFBAIBGAGE=EFGG?DCB?EDEIE@FGAGCEHE?AEH@ICF
@>chr21:9860539-9860632-5
TCAGACGGTAATCTGCTCGAATTAAAACATAAGTGCTATCCATATTGTTAAACTATAAATTGAACCATAACTCCTCGGCCTTCGTCTTAATTTATATATC
+
@IGDHBCCAEAGE?E@D?C7DC@D@@FHHAEHDEG?FCEEAFDG?IGGIHBDB@FIDICAHFDA??EAADCCCFGA@FCBAFGAHEIFBCBEIDDGE?AD
@>chr21:9862662-9862840-0
ACCACTATGCCTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGCAGATTTCTTAATGAAATATATAGCATACTA
+
A?BGEIBGF,IG@IFFAIDHF?@F@D?@CEBHA@?HHDCGE@@GEAHI?CCECIGA@CBDDDBHFDGDFAHGBF@BB@IFEC?CFGD@FFBC?HHFCCEB
@>chr21:9862662-9862840-1
ACCACTATGTCTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGCGGATTTCTTAATGAAATATATAGCATACTA
+
FIFH?IBCII@AB@DBF@IHDI@GGBI@AH???FABHI?EA?DEGIEGBB@G?ICG@@IDEH@?G@HBEB<IBDHCACI?@EFHHCI@IBIF?GIAHGBD
@>chr21:9862662-9862840-2
ACCACTATGTCTGCCGTAGCAAATACTGTCCCTCTTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGCAGATTTCTTAATGAAATATATAGCATACTA
+
FHFHGBG?I?BEFDDFIC@EIIDACIDFC5HHHEECB?F?HEIHA?F@/C@@AADC@@E@HCABGHG@@ADGBDF@FEA?GCF?C2?@H=EFHF@BIBI?
@>chr21:9862662-9862840-3
ACCACTATGTCAGCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGAAGTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTTTTAAACAAAATA
+
?DEDDH?BDAHBABCC?BIDFAAI?FID?ICCC@ID@EBHEBD?A@??@FE?IB@?H?BEHAAFBBAB?IIAAI@BFB?A@GHC@@F2GEBF?IACFGHC
@>chr21:9862662-9862840-4
ACCACTATGTCAGCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGAAGTCTCTTTGCTTCTGACAGGGTGTCTGTTTATGTGTTAAACAAAATA
+
H?BC@AG@?ADC?DFHGIAIFGD@IA?AEAA?@@GIAGAF?GA?CIFACDBECDBECDBBCDG?IDEDHAHGIEFDCBGG9HG@FDIHC@HHBEHH?D@B
@>chr21:9862662-9862840-5
ACCACTATGTCAGCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGAAGTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAATA
+
@EAGAEC@FF?DBHH?D@?EG?AGCEBBA@BIDBI?CFFEGCEDCFIHGEACHF?FEICE@@GFBIEEEF?HEG@HAAABADHDCEAHFGCGBCBE@B??
@>chr21:9862662-9862840-0
CTCATACCACGCTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGCAGATTTCTTAATGAAAGATATAGCATACT
+
?@?BIA?FDHFE?HDAFEHDAHIBG?ECEHCBEBAAEBIDCAIDF@CGHE?DB?D@AEGAHAFFI?HDFGE@CG?GAIE?H??C@CG9AHI@CHDGAF?@
@>chr21:9862662-9862840-1
CTCATACCACGCTGCCGTAGCAANTACTGTGCCTCTTAAGAACATGAACCTGTTTTTCNTCATTTTTTAGCAGACTTCTTAATGAAATATATAGCATACT
+
BGHFEDCH?BB?@IDFE?@ACCF<GCBBFEIAI@BAEH?DBC?GDH@?ACAFIEFAFF/BDHHAEFDHCGB?HC!DEEIADDIEF??II?B@FHF@C?AF
@>chr21:9862662-9862840-2
CTCATACCACGCTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTNCATTTTTTAGCAGATTTCTTAATGAAATATATAGCATACT
+
F?@ICAEG@ADIEB?GFCEEDBGFFFIBBDDCBIHHCDAIICBGGCGBDI?@E@?IDI@=FBC@CCBIF?GABAFDIIGIHFC@HGFBI?AHG?CBEAIA
@>chr21:9862662-9862840-3
CTCATACCACGCAGCCACATTAGCAGAGGGATGGGTGGTAATGGCGAAGTAGATTTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAAT
+
BE?@DBGBCH????AC@CFEIC??AF@HBBFEE?CH@A@@B?E?7DAHA@IAAE6FHB?AF@HH?FBDG@IBHAGF@CHFI?GGH?H@@EFH@GFC?DFB
@>chr21:9862662-9862840-4
CTCATACCACGCAGCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGAAGTCTCTTTGCTTCTGACAGGNTGTCTGCTTATGTGTTAAACAAAAT
+
CGBA.??EF@@BE@HFABDGBFBEAIDHAC@AEGI@HHIABFHG?@IAAHABFFCG?FID?IA@DFHIBFBI?F6FB@FAD?A?EHIEHIEDBACGG?AI
@>chr21:9862662-9862840-5
CTCATACCACGCAGCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGAAGAAGNCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAAT
+
IIAA@CBABED?IBCHIA?HA?:FG?GDDICFEFABHFABBCHCCDF?E5CDIGB4HHADFFDABBACD?ADAAAGHBGIAA@GF?@EB?FCGCEBFACH
@>chr21:9862662-9862840-0
GGAGGTCCTCTGCCGTAGCAAATACTGTGCCTCTTAACAACATGAACCTGTTTTTCTTCATTTTTTAGCAGATTTCTTAATGAAATATGTAGCATACTAT
+
@5?@C?DFCAICG?BICIC?D?AHH?DGBAAGHF?@?7BD?FG?@GC?FFGFIFIC@DBC@FFDHCAHHFBHD?DCGEE?BIDCABCA(ADE?@GID?G@
@>chr21:9862662-9862840-1
GAAGGTCCTCTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTGCATTTTTTACCAGATTTCNTAATGAAATATATAGCATACTAT
+
?CF?DADEEEG?GIECAGA@EAFG@HIECCHDEA@GDDDD@F?HAHFBAFC@IC@?E$HEGI@G?@C&FI?CF3E@3E??C?AI@IA@HFAAFDC?CDG?
@>chr21:9862662-9862840-2
GAAGGTCCTCTGCCGTAGCAAATACTGGGCCTCTTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGCAGATTTCTTAATGAAATATATAGCATACTAT
+
???CHEGG?BDGEIHGI@EFFF@HFC>9BCIAEEDCBCDIDA?IDEGEI@ICF@AFHBB@FFAH?EBEEGHD@?D@IAHEBGDDEBCE@ICF?C?B@BED
@>chr21:9862662-9862840-3
GAAGGTCCTCAGCCACAATAGCAGAGGGATGGGTGGTAATGGTGAAGTAGATGTCTCTTTGCTTCAGACAGGGTGTCTGCTTATGTGTTAAACAAAATAG
+
E??FF@AC@AI?HGCAC.DA?ICD@HABGEEIGD?EHEADE?ADIAI?@DDAIFEA?BF?BBGEB,DAABBEB@BDGCGCAIHAHBEIDIIHA@??@CB@
@>chr21:9862662-9862840-4
GAAGGTCCTCNGCCACGTTAGCAGAGGGACGGGTGGTAATGGTGAAGTAGATGTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAATAG
+
@A?DHGIDD?(E@B@F9DECBFEG@BICF&B?B@H@EFHDAG?EHGHHAHHCF??DIDB?HBIEBGE@GD@HEF!HA@FBAECC?HE?CII?DAAABB?D
@>chr21:9862662-9862840-5
GAAGNTCCTCAGCCACATTAGCTGAGGGATGGGTGGTAATGGTGAAGTAGATGTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTNAACAAAACAG
+
?DGA:CFBECAA?H?FICHGIF=HHBGA*BBDD@@G@IDIEGHEEA?G@EECFIIH??GH?DD?IFA@IGHHFGEFGHBB@EDAHCBAC1EHGFGAE;GB
@>chr21:9862662-9862840-0
GCGGCGTACTGCCGTAGCAAATACTGTGCCTCNTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGTAGATTTCTTAATGAAANATATAGCATACTATT
+
?@HGH?@GEHB@IAABCIBGFFIGG?GGD@HA=FCFCICC?D?F?ECDFCADH?HGGBFDDCICFIC)IDA?EH?IIHFEDHCF)BICDICIB?2IHCCB
@>chr21:9862662-9862840-1
GCGNCGTACTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGTAGATTTCTTAATGAAATATATAGCATACTATT
+
BD?:EACCAHACF?FFFAICI@IIGBEDAICDHHAHCFGG?IICHICBGCIIBEC@?AEFHCACIDB.H?GBBIB?I?DFADAHGCF?C@@@G?HIEFIC
@>chr21:9862662-9862840-2
GCGGCGTACTGCCGTAGCAAATACTGTGCCTCTTAAGAACNTGAAACTGTTTTTCTTCATTTTTTAGCACATTTCTTAATGAAATATATAGCATACTATT
+
F@F?EGHBC?HHH@FECDBCGADEGBBDFBFIIGCGHFGE3C@AC<IEEHD?AB?HFFHBH@?DFGHAE5FHBFH?@CAF??@EHA@G?@BGDH@IBEHE
@>chr21:9862662-9862840-3
GCGGCGTACAGCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGATGTCTCCTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAATAGT
+
DC?FGEC?FCFCI@I@F?EA???AADHEH@E@C?HDFGHAE@G@F?BCIEHH?GCG$ADGECCIBHC?ABD?HDEGFIBCHDCCDDI?@F@HACGHEG@I
@>chr21:9862662-9862840-4
GCGGCGTACAGCGACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGAAGTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAATAGT
+
CABD@??BDCDB)IG?IDHCA?G@BGA?GIC@BFHIB?IBAABFABEDICI@A?GA?FAEBEEHCDFFIFHCCGCABG@BGIAGGHCGII?HA?DE?GIB
@>chr21:9862662-9862840-5
GCGTCGTACAGCCACATTNGCAGAGGGATGGGTGGTAATGGTGAAGTAGAAGTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAATAGT
+
@HH0EADACDFC@AFABB+ICC?IIDFCEBADHHH@EAAEHG?ABHDB?D?BCIDCDEDDFF@IGGGED??IBGCF@GHGBH@DEIBHFCI??I@IHBGC
@>chr21:9862662-9862840-0
TCAGACGGTAATCTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTTCATTTTTTAGCCGATTTCTAAATGAAATATGTACCATAC
+
A@FFF@@FG@@E@BAG??ID?CIIFBBGGHAFDBFBEHBAC?@CGB@?B@EIG?I@DDICGFAEFGIDE@HF"?EHCEDE-?@D@?IBAHI=?@)IED@E
@>chr21:9862662-9862840-1
TCAGACGGTAATCTGCCGTAGCAAATACTGTGCCTCTTAAGAACATGAACCTGTTTTTCTTCGTTTTTTAGCAGATTTCTTAATGAAATATATAGCATAC
+
HBADDBGBIHFG?FAII@?BHIE?BFEAIDEFIIHFIFC?DIGEEDEDHBBDACGHE@B@HG&DFAABFI@?I@BE@)AABBI?DGHH@GFIABGDCIIC
@>chr21:9862662-9862840-2
TCAGACGGTAATCTGCCGTAGCAAATACTGTGCCTCTTAAGAACAAGAACCTGTTTTTCTTCATTTTTTNGCAGATTTCTTCATGAAATATCTAGCATAC
+
D@C?GEEEBHFHGGGIE?@?AECH@GIF@FFED?GBFIFA@A?@D=AGBAH?@?HDGF@FAEHIDCGHG6A?B@CCCG@IC%IBEDGIE@H&?EFIIGIA
@>chr21:9862662-9862840-3
TCAGACGGTAATCAGCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGATGTCTCTTTGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAA
+
EHECAI@GG@BC@EAAAACEDAGD?CEHFBDAII@IAIEDCGCHD@EI@AH@A@FBHHFCDHEC?HD@ACBGIFFE?GDCACEABIFHIGEEAAD?BDBA
@>chr21:9862662-9862840-4
TCAGACGGTAATCATCCACATTAGCAGAGGGATGGGTGGTAATGGTGAAGTAGATGTCTCTTCGCTTCTGACAGGGTGTCTGCTTATGTGTTAAACAAAA
+
@GCH@GBAH@E?GC3EG@@GIBA@B??DD?B@?EC$DABEBAHC@DHAG"IHA?GGIECBCI'EADEI@F?AAHIH@CA?B@@E?IDIDEIGFACGB?DI
@>chr21:9862662-9862840-5
TCAGACGGTAATCAGCCACANTAGCAGAGGGATGGGTGGTAATGGTCAAGTAGATGTCTCTTTGCTTCTGNCAGGGTGTCTGCTTATGTGTTAAACAAAA
+
AEH?@?HEGDAGCGIDDGGC=@B@?CHFH?F?F@HDHBIIHB?@IA*@@IDGCBFI?D?DCHEBGH?CEC.AIHF?B?DGEF??DCFHEAG?GGFHHACF
@>chr21:9862837-9862935-0
ACCACTATGTCTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTTTATCCTTTATTTTCAATTGGGTAGGAGATAAAATAA
+
BFEIIIBH?FHIDGADBAGCEG@AEHECCECDHB?IG?DDDBD?AAFA@HDFADABABEAFAFIGCC@?ID?IF?FFFCGHIFHHGHEDABGEFBDHE?G
@>chr21:9862837-9862935-1
ACCACTATGTCTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGNTCAGCCTAACCACTTTTTATCCTTTATTTTCAATTGNGTAGGAGATAAAATAA
+
HB?HD#@EA@@??DFCA?B@IEG?GHDA@AAG?AABCHD?DGB@E@3@BBCGHFGC<BAA@?GIGEDEFFH?CBBDAHBFEGD/EIAE??CCIAI@?CFB
@>chr21:9862837-9862935-2
ACCACTATGTCTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGGGGTCAGCCTAAGCACTTNTTATCCTTTATTTTCAATTGGGTAGGAGATAAAATAA
+
@DIADCG?I@CHCIA??EGICDCB?HC?2G@CDAEA@EGHHCAE=A.FG?FIFFHIGABCED'ECAEC?@@HCBC?IGCACHAGCBEDIEAA?BA?GABC
@>chr21:9862837-9862935-3
ACCACTGTGTCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACATC
+
CAFBFA#CIFCCCCDAI?@DC?IBEA@@AI?CAABFIGGIIBID?(IBEAGEHBBIAGD?IFGFD@@GFECIGCDAEHIBDH@@GIEHF?HGG@BIEDCH
@>chr21:9862837-9862935-4
ACCACTATGTCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACATC
+
IIBC?FC@@ADD?H??@DBD?GCIIBEHEEDFDHCECFAFCEDFFIGDFH@A@@FIAHAG@EICEHFEDBFDH@IH?C@FGA?ECDEH@G?F?AAAGCCE
@>chr21:9862837-9862935-5
ACCACTATGTCTGNTGAATTCTTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACATC
+
I?G?@?BEA@GBG=ECAECD*GGEEA?H@I@BGFC%A?AHFH@?G?D??B??FHCIC@@EGGF????E@BB?@EEDFBBCDAHDADDAID?GACB@HDD&
@>chr21:9862837-9862935-0
CTCATACCACGCTTCTTAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTTTATCCTTTATTTTCAATTGGGTAGGAGATAAAATA
+
A?FFGCGHE?F@I-IB#CCIEFIEGBIGIGBAA@@H?DDDG<BEHCDFE@CGDD@BHBEGII?EGEAD@HIHCID*CA@HICC@D?BGGEGFEC@GH@AB
@>chr21:9862837-9862935-1
CTCATACCACGCTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTTTATCCTTTATTTTCAATTGGGTAGGAGATAAAATA
+
H@CIEIB@HDHGCIHCCAECCI@DD@BCIIIHAFBBH?ID@HGC@D??EFGD?BBG?DBABEBHFIEGHAEDF?HIFBG?BIEBID?FFI?DGBFHC@A@
@>chr21:9862837-9862935-2
CTCATACCACGCTGCTGANGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTTTATCCTTTATTTTCAATTGGGTAGGAGATAAAATA
+
F?AFFHACC?GHECGAGD9FG@GECDCD?@F??EAFBBHCD??@GHI@/IBHI?@I@HIFEDDDBGCGHGEF@IHAICHA@EA?CCGBCCFBIBIBB@C?
@>chr21:9862837-9862935-3
CTCATACCACGCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACAT
+
IC@AIA@CCEF@CHHECEHEBBEHBEHI@FE?IIDCCC?EBDGHAEGHDCHCDHH<IHHF@@AHE@ABCFCGCAGED?@IBIBAFBFGCDHACIF?@EI@
@>chr21:9862837-9862935-4
CTCATACCACGCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACAT
+
G@DDIBIFBCHBHEEBEC??BGHGD?@EEFHBFGFCCFGGDAAE?D?F?IBG?HHBECDEFC?CHDCEGECCCFA?BDBGDFBGBGCGBEBFD@B?GHEI
@>chr21:9862837-9862935-5
CTCATACCACGCTGCTGAATTATTTTATATCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACAT
+
@EGBEIGCD??BIBDIGGC@FECBIEHG,BCDBCBBC?FHIG@D@CGDCDGEII?CH@GFEFFFAB/@FAD?CFEFAGAEAD?ABFHCFBEE?F@DHD?I
@>chr21:9862837-9862935-0
GAAGGTCCTCTGCTGAAGATGTTACCTAGACCAGAGGACTTTGTGTTCAGCCTAAGCACTTTATATCCTTTATTTTCAATTGGGTAGGAGATAAAATAAT
+
BGGIHC0GFHFGBIC?CCH@IFBCCECB?G+DAFFDH?H*CDEE@HIGFAC@?CHIIEH?@?HGI@FIBIBI?C@?HGIH?BBE??C?IGGAIFDHDCGH
@>chr21:9862837-9862935-1
GAAGGTCCTCTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTATATCCTTTATTTTCAATTGGGTAGGAGATAAAATAAT
+
@??CIC?H@DG@BAF?A?DFD?IDHFEIF@DBB@BI?@G@E?ICBB@??IBG?GIAI@FGHCBGIDFDIID?BCDHFEI@FCCHBEICEFHC@@IGE?GA
@>chr21:9862837-9862935-2
GAAGGTCCTCTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTATATCCTTTATTTTCAATTGCGCAGGAGATAAAATAAT
+
G@?@F@AGDHA@FDC?ED?IE?DAHCE@??@CDD@GBEGHGEBEGG?HEEH?ECCAFF?A?CFCAAC?ABHBBIFFGDH?AE"E5G@FDIAEDAF?CEIA
@>chr21:9862837-9862935-3
GAAGGTCCTCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATATAAAGTGCTTAGGCTGGACACAAAGTCCTCTGCTCTAGGTAACATCG
+
HD?CCE?GBAGBABGHDBD?@C?HGEDE?FAEAFGDCHICHIH?ADHBCCCFHCICCICFEABIBEB+?.ACFBAH@C@HIBHFDDFIAIACFHAEHCB%
@>chr21:9862837-9862935-4
GAAGGTCCTCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATATAAAGTGCTTAGGCTGAACCCAAAGTCCTCTGCTCTAGGTAACATCT
+
DHEDFA@@HH@DE@DHBIA@GCIGAH?EEIGCAEDGEADD?EDIC@EGHF@BIACEABBHDHHIBGEDH@@@*AHAIGA@C?@FIFDCHBFEG@CFEBIH
@>chr21:9862837-9862935-5
GAAGGTCCTCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATATAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACATCT
+
?I?DDABEE@GIHECFCCI?AIFAFI?FFG@@IHAIED@CFIF?BGEIFCHGEAIFFHFEEFE@CE@ABBHHEABGCHEDAC@AGD?B@@@DHH?C@DDA
@>chr21:9862837-9862935-0
GTGGCGTACTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTTTATCCTTTATTTTCAATTGGGTAGGAGATAAAACAATT
+
H+?BCI?IECEECGGC@DBDF?H?EEEBHGCIFEC??GHBHGDFFEIC@C?G@HC?DH@BEIH??BBD?FI@FIFBDGFH?G4?FEBEGBBIFAC1DBBD
@>chr21:9862837-9862935-1
GCGGCGTACTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTTTATCCTTTATTTTCAATTGGGTAGGAGATAAAATAATT
+
FF@CFDEBBBI?BC?CF@HBH?DACDIHCEGGECDGIHGFFA?IGBEAIEG@C?HIEIA@DF@BFF@GFHGAA?GD?BG@?F?HG@DCBIFIDEHGG?HC
@>chr21:9862837-9862935-2
GCGGCGTACTGCTGAAGATGTTACCTAGACCAGAGGACTTTGTGTTCAGCCTAAGCACTTTCTATCCTTTATTTTCAATTGGGTAGGAGATAAAATAATT
+
?DDBIEEE@HGC?DIGHEHCFDBGHBCHH6DEDDAGAB?GHB?EBF@CCAIDG@II@IEBB:?CBA@@FE@BFGHEDAGBDCADI?GEFFDBC?@GIEAC
@>chr21:9862837-9862935-3
GCGGCGTACTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACTAAGTCCTCTGCTCTANGTAACATCTT
+
D?CEHAIIHCG?IEGFG?IFDI@IDEFEIBGDDI?(GEHG?ACI@EBCHGEH?BHGHCDECIEIBDFD@ACFH6GDB@CA?@ADABIAE4B?BCEE?HDE
@>chr21:9862837-9862935-4
GCGGCGTACTGCNGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCGTAGGCTGAACACAAAGTCCTCTGCGCTAGGTAACATCTT
+
ECHHE@BEGHD@8FF@I@?AEGIBHIGAG?FCIFB@EEEAH?H?AHDAI??HFGB@GH?H:BEDCB?HCBBH@DEHFIB@D@EGE4HHHB@G??BCFEAB
@>chr21:9862837-9862935-5
GCGGCGTACTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACATCTT
+
C@H?EHI?IDHD?@IBCB?BCIGBGFID@BIBEDDCGG@DIGIBEGF?@A@BIHACIF??B?A@HEB@ACAFGFIDDBHEICIEB?FCDGBCIABDAFCA
@>chr21:9862837-9862935-0
TCAGACGGTAATCTGCTGAAGATGTTACGTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTTTATCCTTTATTTTCAATTGGGTAGGAGATAAAAT
+
HA?GI?CD@FDEHDEAHGCFD@FHFBCF%@FF@HDDAIGCFHCGFIHIGABCIAGG@AHD?HAIAHIFCCA@FECE@IE?H@?ED@CHED@E@GGD??GB
@>chr21:9862837-9862935-1
TCAGACGGTAATCTGCTGAAGATGTTACCTAGAGCAGAGGACTTTGTGTTCAGCCTAAGCACTTTATATCCTTTATTTTCAATTGGGTAGGAGATAAAAT
+
BE@FHDCHCBII@BE@@FG@F@@BBF?D@IA?HB@ICFCGFI?CD@DB*@IAIBEGEICCIFGBDCIGCAHCFB?HEBEHCHCC?HH@EGF@AIGC?HGB
@>chr21:9862837-9862935-2
TCAGACGGTAATCTGCTGAAGATGTTACCTAGAGCAGCGGACTTTGTGTTCAGCCTAAGCACTTTATATCCTTTATTTTCAATTGGGTAGGAGATAANAT
+
?ABDC@?CII@EE@IHFEHDAHEGAI?CIFB?CFCII1IGIFBIABEFHHDC@G?I?GDDCFCIHDF?HIADGHBH?HGG?IBHI@EIBE@DDGEDD3HC
@>chr21:9862837-9862935-3
TCAGACGGTAATCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATATAAAGTGCTGAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACA
+
EEIFG@BAAH@BHBBHBEA@I@EHBIBDA@BIC?FDCEE@@EG@FCFBGAD@BHEDBDB@H@GAC6BECACIIEFIFHGFDECCB?HF@HI@BGCFE@DF
@>chr21:9862837-9862935-4
TCAGACGGCAATCTGCTGAATTATTATATCTCCTACCCAATTGAAAATAAAGGATAAAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACA
+
BFBEIGAD%BCHIFIAB@B@EBDHG.EAEABCGGE@ABHFBFEDEEEEF@FD?CGI@BGEEEAFF?EFCDBB@AG@FDECHIGGCA?@ID?BFC?GAHGB
@>chr21:9862837-9862935-5
TCCGACGGTAATCTGCTGAATTATTTTATCTCCTACCCAATTGAAAATAAAGGATATAAAGTGCTTAGGCTGAACACAAAGTCCTCTGCTCTAGGTAACA
+
CE,FI?IAIHGCHAADI@EAFAIAC@IHEC?DEAHHI??DICIHH@#A?GHF?ACC$B?CA@ACHCHGIABHCEGI@GDCBBBGHEFA?E@C@B?BBAC?
@>chr21:9862932-9863113-0
ACCACTATGTCAGCAATAAAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTTCT
+
DAFFIHDBIBCEGGF?FGFICGC@A@IBFAI@FADIHFBDIADADCIDGGIHHECBGF?F?A@CEH@?FDAFGBDCGDHIBHDBIAAA@?C@?HIHI@DG
@>chr21:9862932-9863113-1
ACCACTATGTCAGCAATAAAAGTCACGGTTCTTAAAGTTGCAGTCTCACCACTGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACTTGGAGTTCT
+
IHGG?CIEH?HEFIDHH?D?I?EG?G2*CDHGBGGA@A@IHDHDBFDFGIF=EIAB@I?CGI?FEHEACEGGI@C@DADDEIBBBIG?H@%HHG@@E?HC
@>chr21:9862932-9863113-2
ACCACTATGTCAGCAATGAAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTTCT
+
BC@E@DAEBHCFE@DAA(AFDGBDIHEGBHCHIBHCDIAH?ID?@EC?D?DFC@H?F@C@EAAI?GFDAEGBAE?AHI@CGDBF@EDGEFA@AAICAIC@
@>chr21:9862932-9863113-3
ACCACTATGTCTGCAGAGAGCTGCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATG
+
H?IC?IIEG??D?H??GFGDBF2GFA@ADGHHAEEE@CIFE,@DEG+DD@BEDCIEHCC?AC?HEIHFDHF@BACBHIGIBACF@HD?CD@HCH?HAD@D
@>chr21:9862932-9863113-4
ACCACTATGTCTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATG
+
IBHGHED@??DBFIE@EFIEHA?FHA?ICCHECCF@@EGEH@DIB?AI@DBEGG@AG@G@EFFCG@D?HGGA?HB@@CHCEHAIGGIFECIFHCCEHA@A
@>chr21:9862932-9863113-5
ACCACTATGTCTGCAGTGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCATCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATG
+
FHDGFHBHGDEHBCBI(I?B@IABE@ID@HDCDGBHBBA@CE???H@BHBFFFHEDGEA6CFFFHHEICCA?DF?CAEGE@IFEDF?IAHF?IEGDHEDG
@>chr21:9862932-9863113-0
CTCATACCACGCAGCAATAAAAGTCATACTTCTTAAAGTTGCAGTCTTACCAATGCACCACAATGTAGCAGTCTCTCTTGTGNGGTATTACGTGGAGTTC
+
BAGGHCEB@FBCG@AACFIE@BDCBBIH@C@EAFIIBEIDEEFEFFH-ECH@GHIBB@FBDBCDHHBACA?FHEFIE@H@EI>CDEF?!GBEDGHE@GAG
@>chr21:9862932-9863113-1
CTCATACCACGCAGCAATAAAAGTCATACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTTC
+
C?C??FDBGIBCC@G?IHIHHA??E@AHCGFCICHBHC?C@EI?H@BBAEH?E?BF@F@ABHEHGA@EH@@BIFAFGHCF?@A?@?DH?FEDGCAD?ICB
@>chr21:9862932-9863113-2
CTCATACCACGCAGCAATAAAAGTCATACTACTTAAAGTTGCAGTCTCACCAATGCACCGCAATGTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTTC
+
GD?IAE?DGEGABH@HGH@@C?BBBBHGGE7EHDEDA@@??HHAHGHHBACD?HIBDI?)GBE?BHCACBDDHADDBG?HAHFGHHCHHH?HIIGGDFAG
@>chr21:9862932-9863113-3
CTTATACCACGCTGCAGAGAGCTTCCTCCTTTTTNTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATGATCTTGGTGGTGAGAT
+
AG2BECDDGFGGGIF?FAECGBDDDF@ACHBBDE&CFH@CEHECG?D@EGIGHIB?EDAACGAGBAIAG@B@GCA?EDG?A@@%@HIAH?HEDHD@??IH
@>chr21:9862932-9863113-4
CTCATACCACGCTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTGACTCCAACCTCACCCGTGTGTCCCTGTTTCTTAATNATCTTGGTGGTGAGAT
+
C?DCFEBHHDBGDAFCFDBDHIGGCFEG@FCGFFGFBF@EBCDGGBI-BC?FCICEDBIBEE?GGIEHGADDDHGI$E?AFEG1EGAFGBFACGBGDCFB
@>chr21:9862932-9863113-5
CTCATACCACGCTGCAGAGAACTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGAT
+
A?DIDECGFFDCE?C?BFGE'@EF?F?CGBBBIC?DIB?FCHBFI@I@IAIHF@DABIG@AHEB@G@HA?HCACDB!CDGCBC@?HHGI@?IA@CCEDIH
@>chr21:9862932-9863113-0
GAAGGTCCTCAGCAATAAAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTNTTGTGAGGTATCACGTGGAGTTCTT
+
HID?@GF!IIDH?BI@EAIBGI@DF@C?@BCEGHBIC?DICEDAID?A@D@BI?BHICA@DCCE?@AHAHEICA6BFG?ABDBF?IABI@GADHCCEHBI
@>chr21:9862932-9863113-1
GAAGGTCCTCAGCAATAAAAGTCACACTTCTTAAAATTGCAGTCTCACCAATGCACCACAATGTAGCAGTCNCTCTTGTGAGGTATCACGTGGAGTTCTT
+
CCCFDBDEDF?BHGAHAEEDAH?DCEDI?IFFCCA4E@CE@EF@?CAIIAED?@BFIGGAIFDIECFFCGG2AGFEDIGDAGEECF@?GEFEG???EBHG
@>chr21:9862932-9863113-2
GAAGGTCCTCANCAATAAAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCACTTGTGAGGTATCACGTGGAGTTCTT
+
GFEFHHGEI??#H?@FIIEEC?HFB??ECHC??FFH?IEB?DIFHBBBECGADD?AFD@FB?FBCEHFAAIGH$BDGHA@DCBHEBD@D?BIDEDGIFBE
@>chr21:9862932-9863113-3
GAAGGTCATCTGCAGGGAGCTTCCTNCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATGA
+
DC@BBCG+IE?FB?H$DBGDBBAAA6?GAEBCCAFGAEEGHEEGBFGBBF?D@HBIFA?DCHFEBBHFFB/IBECIHD?HDDDHE?HGBHC?@?BF@@DI
@>chr21:9862932-9863113-4
GAAGGTCCTCTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTNCCTTAATCATCTTGGTGGTGAGATGA
+
BCHEHHA??GEDA@@GFGACIF@IDIGHG@AG??BCBGCIA?IFBHIDDA?@?DG?EG@G@IHCCEH@EHHID(AAADHBGBBFBIFEACD?BGBEAF??
@>chr21:9862932-9863113-5
GAAGGTNCTCTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATGA
+
I@HDDC)HGI?GAEHCAC;DB?BEF?BE?@IIFEFCGAI?IH?DDFC<HF@?B@DFH@EAFFFI?D?FBCAFFIBGFGDHAHHBAHIGAE@D@IGCAG?I
@>chr21:9862932-9863113-0
GCGGCGTACAGCAATAAAAGTCACACCTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTTCTTC
+
?EHDCHCFFAGHICIFGDH@HAEGIC=H?DGH@II@?BIBI@EBHCAAB?HEAGI?IAEA@GG??HEIBF@?CGEBECIICGCCE?FC?GI@?IEHE?B@
@>chr21:9862932-9863113-1
GCGGCGTACAGCAATAGAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTTCTTC
+
?AC?FCIHCI?BADCF1IGCDHEC@GB@?CACG?IH@EBI@GBBGHD?AH@>EFI@GBBHCFIEH@BHGBHF@HHHBADAHA@FDA@EA?EEGDGAGEHF
@>chr21:9862932-9863113-2
GCGGCGTACAGCAATAAAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATCTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTTCTTC
+
E?FGCBIEA@EH@BFDAABCCCGII?ADAIDEHAHGDH@FEHED@GBGHH@?HG@CHICDE,BDEG@FCAGCIBFG?GC?@?BFDEAHCFACADCHFECA
@>chr21:9862932-9863113-3
GCGGCGTACTGCAGAGAGCTTCCTCGTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATGAA
+
HAGICDBGCII??HH@@D@F@ADIF7@C?CEFAAHDHAF@IIDEC?I@?CDGDB?FIDFDCHFIAB$CAICEHFBEFEIFIGFA@F?HBCFBEDHGGIFC
@>chr21:9862932-9863113-4
GCGGCGTACTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCGCCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATGAA
+
AIA@AB@BE?BFIFGHFFACHCDHGFGEDFBC?BIICCF@H?CCGBGICHFCABAF;@@HIHBCB?E@ICCFIDBA@IB?@@@HBADCB@EDI@HGGGBH
@>chr21:9862932-9863113-5
GCGGCGTACTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGATGAA
+
@GICACHAGEDBDE@@H@IEDBAD@G@DFACBFAEG?BAHIAFGB@EBIE@GDHAF?EDAFIEFFDIBCEAAECBHD?AB@EI@@HACCD?CI??FIEBB
@>chr21:9862932-9863113-0
TCAGACGGTAATCAGCAATATAAGTCATNCTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTTTCTTGTGAGGTATCACGTGGAGTT
+
EBBIDBIID?F?ABH?FHC@>AGFCA?G#DB@DC?B@E&D@HIIBHDDE@@FBGB@I!??HAD@EAAI@CCHH@A0@@DBHHFAEGH@FHCCCAE@?@DH
@>chr21:9862932-9863113-1
TCAGACGGTAATCAGCAATAAAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACATGGAGTT
+
FD?D@BA@IHC?GHCDAE?DIHBE@HAHDF@?IBFEIAEGB?AHG@FG@AI@@IF@HCF?FFFDAII@DAG@IAGAE@?DHAA6?HCFE?HC4?CF?EHC
@>chr21:9862932-9863113-2
TCAGACGGTAATCAGCAATAAAAGTCACACTTCTTAAAGTTGCAGTCTCACCAATGCACCACAATGTAGCAGTCTCTCTTGTGAGGTATCACGTGGAGTT
+
@FDF@EDCG?E?DCG?G@FDAE?GIDGBHB@@IGG?BID?DIAE?AGDHFHHF@CEF?AGF@CDFAC?ABDBCDB?BECGHBIE@HA@C@FFIFEAFEA?
@>chr21:9862932-9863113-3
TCAGACGGTAATCTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGA
+
EIDHGCGAC?ABIDDEHBHGD@EA@HEGGEDFDDEFFGCCHCHAFDCGGFEEHD@EDBACFEGFIHH@IEIBFICIBCHGD@@IB?AAH@IAD@B@ABDI
@>chr21:9862932-9863113-4
TCAGACGGTAATCTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGA
+
ADGDEHED@@?A@ADGFHDC??GB@CBGED?BFHAEHDDC@EC>B@AHAICDH@FHHIAA?BGD@DBDCCG?IFDGC?CHFAHA@C?@FDFEFHBGAIBG
@>chr21:9862932-9863113-5
TCAGACGGTAATCTGCAGAGAGCTTCCTCCTTTTTCTTATTAAACTTTCACTCCAACCTCACCCGTGTGTCCCTGTTCCTTAATCATCTTGGTGGTGAGA
+
@FA?AEGCCID?HEFFEIFIHHAIFFE@EHICBFFIECFIHD@F?GHCBDBCFEH?FIHHBD@BEEHGAFBBDEE(IDABBFFII?EE?BHI:<CGAFAI
@>chr21:9865834-9865956-0
ACCACTATGTCTGCTGCTCTGCTGAATGAGAGAAGTCCCTCTCCAGTGAGGCAGAGNAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCAC
+
BDAAEECBDHCEC@FGHG@FED?GCEHAH@CDEGBC@GFDDF?@A??E@IBB@DBH-IDCCCHIAHFHCCHGGABI@?AGAHHAHHG??EIACD@IIEIE
@>chr21:9865834-9865956-1
ACCACTATGTCTGCTGCTCTGCTGAATGAGAGAAGTCCCTCTCCAGTGAGGCAGCGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTTCATAGCTTCCAC
+
IFDDIBD@BGHHHH?IFE?ACIFCFCG?@EH?IC@@@I??C@??F@DIAB@EGD!ACAIB?ACDEBH?EEG@H??H?FGII@HG@FD4@FIAIBE@AAHA
@>chr21:9865834-9865956-2
ACCACTATGTCTGCTGCTCTGCTGAATGAGCGAAGTCCCTCTCCAGTGAGGCAGAGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCAC
+
HGBH@FAHG@C?@@DCH?DA?@IFID?II@=FCDD?EDDCGCDC?CAH?DG@ECICIDED?GIGHDEHECBHBDCHEGADGFHB@DBE?DBEC?DCGGII
@>chr21:9865834-9865956-3
ACCACTATGTCAGCTCCCACACTGCTCGCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACTGG
+
?DEH?BBD@?HAFFCGCE?EHI?I@@G8DFHDIGBIEFGB@@@CGAGG?FEFEBFCBCGEHBIB@BIAF?CIIFHDHFF@DDABAG@DHE?HACH@F??D
@>chr21:9865834-9865956-4
TCCACTATGTCAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCATCCTGGGCTCCGCTGCCTCACTGG
+
9CDHAEEDACHCH?CDAIIBG@I?HEEBACDEGFI@?FCGC?IABE?IFE?HGA?DHIFFBBCHBCD?BD?EIAGC<AB@E?CE@IB'FDG?I@DHFEHC
@>chr21:9865834-9865956-5
ACCACTATGTCAGCTCCCACACTGCTCCCAGGCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACTGG
+
H@IAFHIDHFFIIAC?@I@ABCDD@CFGEB?#HAIH1G?FHCIIIIADEEGGACAHIGIABDD?FHHFA?IBICHBGICIH@FII@AHFGFCFCDCEFH@
@>chr21:9865834-9865956-0
CTCATACCACGCTGCTGCTCTGCTGAATGAGAGAAGTCCCGCTCCAGTGAGGCAGAGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCACAGCTTCCA
+
IEC@BA@AIDAE?HD@DDHBGBFAC@GCA@@HG@AG@@ACHBGHF?FEEDEGAE?DDGACIBIHEHBGCCDFHABHHEHGAHHFG@AI@?H(DEGG?@@?
@>chr21:9865834-9865956-1
CTCATACCACGCTGCTGCTCTGCTGAATGAGAGATGTCCCTCTCCAGTGAGGCAGAGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCA
+
GAIH?@GC?IFABICBEFHB@ACDAID@C@BDHH;GA@@D??DDHH@BHCCDFBFGFECA@CB?FBA@EBFB??@AIEF?D@HCCHABEACEFEBDBHEC
@>chr21:9865834-9865956-2
CTCATACCACGCTGCCGCTCTGCTGAATGAGAGAAGTCCCTCTCCAGTGAGGCAGAGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCA
+
IH?FEEI?@IHEGCE$@BGEBABDFF@D@CCAFAF@@CGDGCAG@HHBEAHBBFFFIHD?IBAGDFIEA@GD?HIF@GGBDECD@FAGFBFCICEBC@=@
@>chr21:9865834-9865956-3
CTCATACCACGCAGCTCCCAAACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACTG
+
@HGDEBEBBGACBIFAI@BF-@ECGBDG?H?GBIFHCBDBBDBCFAH@EAGGGDB@IHBH@?FIDDBDGCAGEFBIEC@EE?CDFGI@H?BHA?GC?E?C
@>chr21:9865834-9865956-4
CTCATACCACGCAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACTG
+
EHIHDBDF?B?ABBBAG?BHEDA@G?GI@BGGHGFGD?BCAGF?@@ADCDCCGHCG@G@EI?IGCACD??A?DI?CCFGEH?F?CBFEHIHCC5CCCECF
@>chr21:9865834-9865956-5
CTCATACCACGCAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAAACAGGGCTCCTCTGCCTCACTG
+
EGH@@?EDFFEGDFCABEBCAA?BFCIE?EECGE?FFIBCHDC@CGEGDEACHHADCG?BADCEBIHHC+EGFBDH@B%E+E??EHGBAAAB@DBBHDE@
@>chr21:9865834-9865956-0
GAAGGCCCTCTGCTGCTCTGCTGAATGAGAGAAGTAGCGCTCCAGTGAGGCAGAGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCACT
+
@GCF@8@F?CE?HAFHF@DFFFDEIFDFBCBFCBI52EIBHFIFI@GC?EF@CAGE@AIAA?CBI@C@FAICFEDA@IFD??C?F?HBF?@BDG?HGDEF
@>chr21:9865834-9865956-1
GAAGGTCCTCTGCTGCTCTGCTGAATGAGAGAAGTCCCTCTCCAGTGAGGCAGAGGAGCCCAGGTNGCACACCCTGGTCTCTGCCTCCATAGCTTCCACT
+
HDFFHGA?FGA?BGFDGFEFAD@CAGBFEGGCBHC@CCEI@AFDGADFH?DDGBDIAEI?CBD@G:AEHC?I@CHEIGGE?CEF??HCBCCHC?GDCDC@
@>chr21:9865834-9865956-2
GAAGGTCCTCTGCTGCTCTGCTGAATGAGAGAAGTCCCTCTCCAGTGAGGCAGATGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCACT
+
EC?C@HBHHHEE@H@IA@G?HI@FDFAI?CEHHBIHF@BE@HHGH@HIFBCEB@/@AEF@AHABGECEGHFCFBGFIDI?EF@AI?DB?I@EACIGDDHC
@>chr21:9865834-9865956-3
GAAGGTCCACAGCTCCCACACTGCTCNCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGTAACCTGGGCTCCTCTGCCTCAGTGGA
+
G@HDHGID;DIBGC@BB?HHABGBG?2II?GIFA@HC?CBCHDHGE6GAC@DDDID?BFCC@EHAABAEGDII>?GGCDEHA?AFGD@GBAB?AE&IF@D
@>chr21:9865834-9865956-4
GAAGGTCCTCAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACTGGA
+
@BDCDCF?GAAIIHDAIGI@AIE?@DHFBFBCCHFCHIIF?CHDADB?A@DGEC@CD?BFEDCIEHA?D??HE"CIAIIDFED@CC@D?CECAEHAA?HC
@>chr21:9865834-9865956-5
GAAGGTCCTCAGCTCCCACAGTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACTGGA
+
H@F?ECIEGEGFGC?AIBIG.CGF?EHEE@@G?FHICBCAEIDDBCB?IBAFGCGIAHDBCBFCEECCCFEHA?B?E?E@@BFCCHE?DA@?ABHBAFID
@>chr21:9865834-9865956-0
GCGGCGTACTGCTGCTCTGCTGAATGAGAGAAGTCCCGCTCCAGTGAGGCAGNGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCACCG
+
GABE@F?EABCAEFAEEIF@FIAGHD@@D@GDE@EEDE@??GAADFFHECHD"FF?E@DGFEIBGH?HECHCFE@G?AB@AFI?EHFFAGE@DB?FHA/G
@>chr21:9865834-9865956-1
GCGGCGTACTGCTGCTCTGCTGAATGAGAGAAGTCCCTCTCCAGTGAGGCAGAGGAGCCCAGGATGCACACCCTTGTCTCTGCCTCCAGAGCTTCCACTG
+
GG@FEGEDDD?HIF,BFA@G@@ABH?BHFFA?EECAF?ACGDAIGAIHGFADCABBBIGB@HH=GCIDACFFDE%DCBHHGA@HHGEC;ADGCHH@@HH@
@>chr21:9865834-9865956-2
GCGGCGTACTGCTGCTCTGCTGAATGAGAGAAGTCCCTCTCCAGTGAGGCAGAGGAGCCGAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCCACTG
+
?@D?@IBCFDIGCDIFIAGE?ECDF@HIII?FHGEACEBDC?EIH@C@I@IDDDHAE@B;FBGIHG@CHEE?BHB??ABHFDH?CF?BIIBEAF@A@IDB
@>chr21:9865834-9865956-3
GCGGCGTACAGCTCCGACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACTGGAG
+
HFDGDEFIBHHBE$F3HIFD?IE@EEDIAB@GAEBGGIDGIAD@BEGCB@EFCDFFGBFAGCBG?FBHFDIGE?FGCHFCGF@@@CFDIH?DGH?GIA?@
@>chr21:9865834-9865956-4
GCGGTGTACAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGGGCTCGTCTGCCTCACTGGAG
+
BICC$B@DEA@IA@HBEGGCCICCIDHC@EHBFEEG?I?DH?G?@IIBIDHBA@G?DGIFA?@AEFDE?BH@FDGDIHCAHDID5?C1IGBIHBC@A?DA
@>chr21:9865834-9865956-5
GCGGCGTACAGCTCCCACACTGCACCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCATCCTGGGCTCCTCTGCCTCACTGGAG
+
@IG?@HACG@CCBDGGIBHE?@I6FG@IEDBH@HHD@F?DI@DCI@CAGEGI@AACAEBEAF??GACB@@BAAD5AAEI@?FAAIA?8?FAFHCD@@GFC
@>chr21:9865834-9865956-0
TCAGACGGTAATCTGCTGCTCTGCTGAATGAGAGAAGTCCCTTTCCAGTGAGGCAGAGGAGCACAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCC
+
?CHBEHH@G?EC@HI?CB?@IBEGADEDBDGCE@IHGEAGDC;DAF@HC?@GGDCD@HGIE@=D?BIIBBDG?FAAA?@IFDD?@EAGI@IFF?B?@EEC
@>chr21:9865834-9865956-1
TCAGACGGTAATCTGCTGCTCTGCTGAATGAGAGACGTCCCTCTCCAGTGAGGCAGAGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTNCC
+
B?DBHGC?CAGFCH?AI@CDAI@DBGB@FFGEEEA+FAFHFI@@BHCGIECCFIBGFHF?@?CIECBEDIE@FIC@GHFCHDB@?I?CAFCFIFEAH%EI
@>chr21:9865834-9865956-2
TCAGACGGTAATCTGCTGCTCTGCTGAATGAGAGAAGTNCCTCTCCAGTGAGGCAGAGGAGCCCAGGTTGCACACCCTGGTCTCTGCCTCCATAGCTTCC
+
EBA@B@DGECIGD@HB?BBIH@EF@CG@HBHID@BHA@6I@FBHFGEIGGDEHCBI@CEI?FIBE?CIACI??GEABAIDDBFAAHFFCI@?DII?EBF?
@>chr21:9865834-9865956-3
TCAGACGGTAATCAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACNAGGGTGTGCACCCTGGGCTCCTCTGCCTCACT
+
CI@E??I@@DEABICC@H?ADCF?I?EGCGDGGHGGEAHC?CIAIB??BBB@?HIH?DIFIEIIEED9?IGIFAEGI?.FDDIF@BBHE?I?F@HIE?EG
@>chr21:9865834-9865956-4
TCAGACGGTAATCAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGAAGAGACCAGGGTGTGCAACCTGGGCTCCTCTGCCTCACT
+
GFED@DHGFHIHFFI@D?@?DDDHAHA@I?@EGAHHDBBG?CEE?IG@EDGAH?FBAFI?%DGFBD?D@IGGIBDB@EFGDGCEH?EBCCIGAADCIFG@
@>chr21:9865834-9865956-5
TCAGACGGTAATCAGCTCCCACACTGCTCCCAGTCCTGGGCACAGTGGAAGCTATGGAGGCAGAGACCAGGGTGTGCAACCTGNGCTCCTCTGCCTCACT
+
AFGGF?DHGEEAAICDAF?DCDCAABD?HGIGGCECCBI@ECDGHHFHCH@IF?@HD@CCHCCFIIGC@??EFD?HFBF?EB;#DBGFDCCGDBBCFGB@
@>chr21:9870488-9870546-0
ACCACTATGTCTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCGGAGATCGGAAGAGCGAAAAAAAAGAAAAAAAAA
+
DFGCFFFGIHCHFEBCH@F?II?CGBAAFHE@FDCFEAEDIB?GG?ACGAAIFDA??ADC@GCABBC@FH?C@D@EAB@?CAIDDID?DH#ACCAB?I@H
@>chr21:9870488-9870546-1
ACCACTATGTCTGCAGGAGGACCTCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCGGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
AE??H@?D@?BFBDHFAGI?DF5EIEFIGG@CC@FBHBE@?ACEECB@DGEGBCI@CI?CBDBCCE@IGEFGB?GIE@F@AGAEAIDD@IFFCICBABCH
@>chr21:9870488-9870546-2
ACCACTATGTCTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCGGAGATCGGAAGAACGAAAAAAAAAAAAAAAAAA
+
CE%DBGH@II@AADHGFG?FHDEA?ADI@AF@IHAFDHIEGCCAD@D?CDH@GI?EDDFIDA?HHB?D?0GDDDDAB1D4BCIHC?HHD?D@CBA@IHEI
@>chr21:9870488-9870546-3
ACCACTATGTCCGCCTGATTTACACCTTTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGNAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
DIIGGBIEH@GHDAGCD?EEED?EC?C*BBE?EEHDDD?EAGIHCHF?D@GAA@E:CFAGHE@?@6G?BCAAGE@IFECA@H?HICADGDDBBBEA@A@E
@>chr21:9870488-9870546-4
ACCACTATGTCCGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGTTCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
@BAGF@@GF@D@G@HFHEADH@?BBAEH?EFBCBDC@IFADCEDIFGEBH@GH@?GECD@AF@IG@EEEC*DIG?IFAH@GAG@AHAG@GAD?FH@EABB
@>chr21:9870488-9870546-5
ACCACTATGTCGGCCTGATTTACACCTGTGTACTGGGTCGCCANCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
HBCI@CEHFDB#E@GHIDEIABD2B?BGCGGIE@HIDGI5@GH%F@E??CEIFI?AEGEADBD@GDDD?GIF?D?FECD?B@H?HEFC?ECHBACIGGDA
@>chr21:9870488-9870546-0
CTCATACCACGCGGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTACATCAGGCGGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
IIDHEHAEBFD?*AEIFGC?@BB?GECCDDGAEIHGIBCEFGG@@HI?BHBIGHCBFHA-A?ADDEGDF@?EEFCGHIB;AGCDEHCB?HBH?ADEDC?B
@>chr21:9870488-9870546-1
CTCATACCACGCTGCAGGAGGANATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
?IGHIEIE?CGDIHC?B@DCBD8FCGG@HHHIFIDE?HA@AIGGDCDIHFABICDFGAHDC@EA@CHE@HHBBABGCGDAGF@FIE@?I??IAF@??CHC
@>chr21:9870488-9870546-2
CTCATACCACGCTGCAGGAGGACATCAGCCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
HACE?AIHAHAAHGAI@BC@BCDII@GF7DGCA@FFE?HBHDEFA?GAD@@ICBAEIAHGI??B?FA?AHD@@#AHB@@AEBGDBF@@?IHB?AFDC@GE
@>chr21:9870488-9870546-3
CTCATACCACGCAGCCTGATTTACACCTGTGTACTGGGTCTCCACCTCGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAGAATAAAAAA
+
GBHBCB?DGCHEBCIAA@?A@?BG@G??@@IGECIIFD?D?BI@E@B3BAADHGC@FB?FGEA@ECC@HII?BCH?B@ACEIIDID?AFG:D?:?DGEFC
@>chr21:9870488-9870546-4
NTCATACCACGCCGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
&@F+H?I??BGGFB@C?FECIA@HHBI?FBGBFEI?@DAF?@GHIFGCCDFFAFEHD??@@DIFG?EI?FDAE@@HGGIDCGEEEI?IIIIGAFIA@ABI
@>chr21:9870488-9870546-5
CTCATACTACGCCGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
FIGDGGD*EE@GABGD@@FEIDIE@EGAFBHCH@E?EICH@FGDEBH@AA?DHCII@AA@?GEBA@AAE?@H?A?CGD?GC@GA?BAFHDD?AFD@IECF
@>chr21:9870488-9870546-0
GAAGGTCCTCTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGTTGTAAATCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
ABGEEACE@FCCHEECEIGAHB@HFFHDCCB@I@E?GHIFIE?DE@CDDFCE0ACAG@DGCEFHC@?EFDGD@EECGEHDHI@AEAAA@B?CHEEEIGBE
@>chr21:9870488-9870546-1
GAAGGTCCTCTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTGCACAGGTGTAAATCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
H@@GFACDFHB@@BIEACAGDIEIDBGEEDIE?IFB@BCDBBDBCC:B@FBD@?ABD?FDEFFIDIHGFGGEDBIGHADDE@CAI@DAF?AGFCA?IH?H
@>chr21:9870488-9870546-2
GAAGGTCCTCTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCNGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
?IBFAHGBECCI?GGE?@H?FGD?IAIFBE@HE@DBAD@GEBGIDHBIH?HCG?EE@@IEA2BFIDECI?EEFBFHBIEHICFEABECIDBDBBIHDADA
@>chr21:9870488-9870546-3
GAAGGTCCTCAGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGTCCTGATGTCCTCCTGCACAGATCGGAAGANCCAAAAAAAAAAAAAAAAAAA
+
DDEEE?@HIDEE??@DEBICIIH?B?GDF@CG@GCHEEGDDCFFACHD(?CA?AHEDIABBBBB@I'DIBCAEFGHID'@%DI@BI?ABEDEGGCECIEC
@>chr21:9870488-9870546-4
GAAGGTCCTCGGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
D?BAIFB@AD-BG?BA@DEA?IGHEIIH?EHI?HGBEIEGCIBIG@FABDI@@?I?HDGDDAA?IH?DCE?CD@GBGIBDIGFABD?IA?F?CI?EG?FI
@>chr21:9870488-9870546-5
GAAGGTCCTCAGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGACTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAACAAAAAAAAAAAAA
+
DICEED?IC?BFHEGCGE?GEGAIID?ICACH@HAFGH@AG?CICC@E@=I?CA?ACFBGBBG@BE@HEE?@HAEBGE@DDHICHF%FGD@BHA?FGGGB
@>chr21:9870488-9870546-0
GCGGCGTACTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCGGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
E@HICDIB?AEEHDE?@IEIBFA?BBC?GH?@?@EIEFFIA?HIDFFEEFEAADD?CA?IAIFGG@@I?GIFFIEDBIIF?IFABBIABIHCAADCBEHC
@>chr21:9870488-9870546-1
GCGGCGTACTGCAGGAGGACATCAGCCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCGGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
FH@CBCBAIHGDECACFCCBDHIEG.EGHB?BAIIBH@HIIBBCBFHIFADGDDGAF?EG?HD???@CFBFF#AD@HFC?GGCAGGFABGHB@@C@@ADF
@>chr21:9870488-9870546-2
NCGGCGTACTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCGGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
,I@@C?FAF?IG?@I?DIDADH?DGBGE?CC?GFCADDBFF@BCFIBFAD?FGD@AEGECDF@FIF@GFDDC?GFEFFEH?FICBHF?FEIBHGIED@H@
@>chr21:9870488-9870546-3
GCGGCGTACCGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGACCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
D@BBGEID?BDBBEEGCAFFBHADH??@FBIBGHEGIGCAEHFIIGBH@D?CIDGBFAIIHCHB?I@AA*BAAGFIFDAHBIA?ABIHF?HE@IHCDFBB
@>chr21:9870488-9870546-4
GCGGCGTACCGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
FA?EH?GBIGI@EBGCFF?@:EDCECDCG?G@C@EBABFHDGE?FCDBIEB@E?@?AAHI?C@@F@DHCHFBHHA@ICDDCIAIHA@@CHEF?FE@HD@E
@>chr21:9870488-9870546-5
GCGGCGTACCGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAACAAAAAA
+
DEADIDEH@DGDAIIDE?IFFDDIFD?FACFIHBFFGHFID?I@CAFGE@?G@GC?IGEEACCCFAGAIECH-DBGFA@AIIBGF@EAAEB@E3AAE@H?
@>chr21:9870488-9870546-0
TCAGACGGTAATCTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCTGAGATCGGAAGAGCGAATAAAAAAAAAAAAA
+
EC?ICGE@ADGBHABFDBHG?BFHA@D@@A?HABIGG@F?HB??C?EH0HCCHEHIGHFDFIBEA@FC?IG@AEDHBCI@@CFHFA$II?@GGDE?@AEF
@>chr21:9870488-9870546-1
TCAGACGGTAATCTGCAGGAGGACATCAGGCCCCAGGTGGAGACCCAGTACACAGGTGTAAATCAGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
@BGACFDBCHI?HFIGGEAE?CEHDHFD?IAIDECH?BAG@?AB@@FCF?AD?BBDGCAGH?@IF@FEHGDHH?DCD@ADAIF@@B?IHHGDC@G?B@B@
@>chr21:9870488-9870546-2
TCAGACGGTAATCTGCAGGAGGACATCAGGCCCCAGGTCGAGACCCAGTCCACAGGTGTAGATCAGGCTGAGATGGGAAGAGCGAAAAAAAAAAAAAAAA
+
EAHBCGDBAG@FCEAGCFF@DDIGDIIFFGC?DED?HA2GIEHEAB?HH$GD?EE?GGEI9DFGD@AFHB@IFI/HBB@IGFBFE?DBHHGI@?CCII@H
@>chr21:9870488-9870546-3
TCGGACGGTAATCAGCCTGATTTACACCTGNTTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
BC!G@IEBCBD?2?DFFB@EG@I@@IAGFH=/FGGDHGEBIG?D@FECCEFADEDDEIC?IC#EHD7B@BI?E@HAFCB@@AIC@H@DF?AIAHHF@I@I
@>chr21:9870488-9870546-4
TCAGACGGTAGTCACCCTGATTTACACCTGTGTACTGGGTCTCCACCGGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAANAAAAAA
+
IDBI6IH<EA-EGH)ECCCAGEI?IHIHC@EDFAIA?CHFI@IDIII%IGI?EI?AFFDGIACE?HCHD@CCHCHHIDDBE?GB@IIHE@DF?8FECGFE
@>chr21:9870488-9870546-5
TCAGATGGTAATCAGCCTGATTTACACCTGTGTACTGGGTCTCCACCTGGGGCCTGATGTCCTCCTGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
H?DEG2G?EFEADAH?GEEF@BBBHA@?HBH?IF@AG@BDGCBFC?BCG?EBCBBCBAHCEBEF@G?AF??EIGCHFCA?@C??D?AFDGGB@?CHFHFH
@>chr21:9873572-9873697-0
ACCACTATGTCTGCNTACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGACTA
+
?B@AECAEGGF/HH#F?B@HD)GIAGHDCIE@I@AAEE?GDGAA@D@EGHHCI?FBECI@BE@@B?DBIG@HBC@GDIE@FDECI@AHEIDH@?E?A?G@
@>chr21:9873572-9873697-1
AACACTATGTCTGCATACCAGTCCCCAGGTTTACACGAGGCCCCAGGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGACTA
+
D8HIFCA@GHAACB??@G@GB@IAG@FFBHC@BBG@?DH@AFEDB'F@AFDFEEDDG@GGE?CEA@?CBCEGFH?%HHD?DBGC@FEE@IF?CEAFDHEE
@>chr21:9873572-9873697-2
ANCACTATGTCTGCATACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGGTGAACATGAGGTCACCAGTAGACACCCAGGACTA
+
H$@FFEDIBEBGFGDBEGC@AA?GADCCIHIAI@E@FAH?BH@A??CCGDDDFHEFE@?E@?CFI'FGCA?IIB@GFAH&?B?D?GC@ADGBEBG@HFBF
@>chr21:9873572-9873697-3
ACCACTATGTCAGACAGACGTCCATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTACT
+
@?HGGIHDCEEDEHIEBHAGAFG?CDACHIIG@A?HCE@IEHBEFFII@DACHIF@@@CDEBDDIB?CBECAID@DDGGBGB?FDHC@FBECEI?HBFIA
@>chr21:9873572-9873697-4
ACCACTATGTCAGACAGACGTCCATCTGATGCTTGATGTGCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTACT
+
BBABBCDCFGAFIIICGBCH?BECF?CA@DEGB?B??GA8E@ECE??&I?@A@AHIDBFFBDGG!CFHGHHBBAC@C@@GH?BI?EFHBDAIBA@FH?F?
@>chr21:9873572-9873697-5
ACCACTATGTCAGACAGACGTCCATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGGCCTCATGTTCAACTAGAGCTTAGGAACCTAGT
+
H@G@AGE??@CCH?G?@FIEFGF??CGH@@IDGBEGHBHDADHGAB?DCB?ECH?BAFHIIABDIEE'BGIDF@BEGFH??C@AGFAAFBF?DEB?B@!E
@>chr21:9873572-9873697-0
CTCATACCACGCTGCATACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTNCAGTAGACACCCAGGACT
+
HGID@@A?@@AEFFAGFIH?BIABEBFHI9?ECHD@BDFDB?DHBEB?B@@HDEHAII@?HF?GAAGD?HFDG?@CDH@@B1ABIAGEFEFIGCD?DAF@
@>chr21:9873572-9873697-1
CTCATACCACGCTGCATACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGACT
+
EAA@CHAAEBGACEA??DBF?FBFDDAHCCBDHABAE?HG@HIDBCAIAHH@D?CDAAAF???BEA@FBFBGBGC?A@GCFE@H@DACDB?BIDH@G8DB
@>chr21:9873572-9873697-2
CTCATACCANGCTGCATACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGACA
+
HGGHADE@C/ABE?GIF/FFGBE@DACE?I?HBGEAHIDFD??B?@DHGAGE?DHDFEHEDG@BEGBEBBHICHD??@BCBEDHEH?DGIFFGGGGB@@2
@>chr21:9873572-9873697-3
CTCATACCACGCAGCCAGACGTCCATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTAC
+
HFAEE@FDFEDIEFIFGCIAGD!FHED?BDDCHAAHD@D?FCEIFG?EFGDBGHFECCAG@@@FCCE@F??I@DBBEFG@GHCGDCDAE?IEBDI@HIHB
@>chr21:9873572-9873697-4
CTCATACCACGCAAACAGACGTCCATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGNAGACCTCATGTTCAACTAGAGCTTAGGAACCTAC
+
C@DCEGECFBEHC4IAEHBED@@FGBBDEEH@?GGD?E?IFBHC?B?C?@DBF@?BAEI@AD?@A;BCC@G@@IAHAII@@D?EFC?IHBAE@EHBAFG@
@>chr21:9873572-9873697-5
CTCATACCACGCAGACAGACGTCCATCTGATGCTTGCTGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTAC
+
E?EDHA?FDCGED?FDCAG@GABGBAI??C?GDBD?-CGB@HIICG4DGGGECCBBFF@HCHBB@EEE@ACFIDIB?GCHG@AAIAEBFDCIGDC??FEC
@>chr21:9873572-9873697-0
GAAGGTTCTCTGCATACCAGTGCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGACTAA
+
GFD?IA#FDH@CBHHHI?AIE4BII@DCD@DCFDFGAE@CCHCDHHBGIEC?B@ADFGBFD?E@?@AF?BHDDGDIDCBEDGBHBIC?IHDIGCHADBGB
@>chr21:9873572-9873697-1
GAAGGTCCTCTGCATACCAGTCCCCAGGTTTACACGAGGCACCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGACTAA
+
AFB@HGHGIBGGBCBHHDBIAHHAEFG??DECIAEFCD@F.BF?C?FA@@CDHFGBGBEADCH??E?H?GAED@HDDBCI?DD@BFCHBCHCBFDHDCGE
@>chr21:9873572-9873697-2
GAAGGTCCTCTGCATACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGANCATGAGGTCTCCAGTAGACNCCCAGGACTAA
+
EFGCA@HBGDA@?ECGCF?BAGAFIBICFFADEEAD?DA?AE?EBGIHCI@ABEA@HDEEIGF?EDH@:I???E?C@?BIG@ID?HHB"B?BDIDBFE@B
@>chr21:9873572-9873697-3
GAAGGTCCTCAGCCTGACGTACATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTACTT
+
D?@IHD@GC??@D@5H@AFC7AHEBA@IADBCBFEI?HBIIB@IHGBDH?DGB@?IGHGEH@EDHGHDGBFEDIAADF?GFA?F?@C@@CHE?FE!CA@A
@>chr21:9873572-9873697-4
GAAGGTCCTCAGACAGACGTCCATCTGATGCTTGATGTCCACCTTGGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTACNT
+
?FHDEG?@BHCID?EA?AHB@CCH?BHDHE?B@AFBAB@E?CFIA>DDFDF@HICIBAGA@DCGDFEEG?I@EDEDH@GICBD?E@CHE@BI@ABHCG'G
@>chr21:9873572-9873697-5
GAAGGTCCTCAGACAGACGTCCATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGTAACCTACTT
+
?F?GBIE@HBBHH?BI@A?@ECGC??HHDCA@@ABG?A@HEHICFAAHFHA?BCDCDDDDF@FAHEBE?DEAGBGA@?B?AD@FBH??BF<ICGGCBFDF
@>chr21:9873572-9873697-0
GCGGCGTACTGNATACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAANATGAGGTCTCCAGTAGACACCCAGGACTAAG
+
CHICIA@C@HA"?GCDD@@C?FIBECHF@AGECCA@?EE?DFCHFGBAGBA@IGGHB@?EC0?I@CID4BIC@FHGF@?A@FDDHFD?GFFEAEIE@DBC
@>chr21:9873572-9873697-1
GCGGCCTACTGCATACCAGTCCCCAGGTTTACACGAGGCCCCAAATAGGTTCCTANGCTCTAGTTGAACATGAGGTCTCCAGTAGAAACCCAGGACTAAG
+
AEAH@6?BB@I@CBDGH@EDE@FGCFCCIB@EDDCA@B@HF?F@6HEB?IGHFEF9FEH@AGGBEE@GFFHAC@@HGGCEEFI?@?5E@E@IHD@@FIFH
@>chr21:9873572-9873697-2
GCGGCGTACTACATACCAGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGACTAAG
+
HDCDHDCECC4F8I?HCCHHCCECH@?C@IEGCCHIACI@C?HHHCC@ABB@CHDFFID@FB?AIGEEFA@B@HEAAEFB?BFAC'@GAFCBGEACBI?D
@>chr21:9873572-9873697-3
GCGGCGTACAGACAGACGTCCATCTGATGCTGGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTACTTG
+
?ICDHDCFFD@B?EDEGGCAEFGFCD@FI1H-EIAG@IEBADGFECHD@F?IDHBF?DD?AI@CFGAFCH?AHFFHG?DHEEC@EAACFHIH@E@AF@EA
@>chr21:9873572-9873697-4
GCGGCGTACAGACAGACGTCCATCTGATGTTTGATGTCCACCTAAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTACTTG
+
FG?CBEGFGHD?ACB?DEAIA?IBFDA@D3CDCF@IHCECFBD3?ADBDEFGIDEBDEBEIDAEDFDIFFB@CF?GAAEC?DHFBGCABA?AA@?ABAG@
@>chr21:9873572-9873697-5
GCGGCGTACAGACAGACGTCCATCAGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGAACCTACTTG
+
CHGIDIHDF?DG@?CED@?HAEHG;EGB?FI?AH@@IGAICFBEADFE1FHFA@C@EBBBDEHBEHED@AHFFH@CHFIGGH@G@EEFACFBGCBD??A@
@>chr21:9873572-9873697-0
TCAGACGGTAATCTGCATACCGGTCCCCAGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGAC
+
GFC?HIFFBGGFIBIDCBEHB(E@FB?CEEDHABBFHBAAEEFBF@DFF@GIGEBBD?+BDBBDCEGBGGAADBE@BA@?EEA?CC@E?@CCDHDEH@D?
@>chr21:9873572-9873697-1
TCAGACCGTAATCTGCANACCAGTCCCTAGGTTTACACGAGGCCCCAAGTAGGTTCCTATGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGAC
+
A?CEHG'HIIDC@CCF@3CHE?@BD?I=C@E?DBHBAF@CCACCAEEHAIGGIHI?EFA#D@?EID?GB@E@EGI?GIGAECCGAB@GAFFFG@DDCID?
@>chr21:9873572-9873697-2
TCAGCCGGTAATCTGCATACCAGTCCCCCGGTTTACACGAGGCCCCAAGTAGGTTCCTAAGCTCTAGTTGAACATGAGGTCTCCAGTAGACACCCAGGAC
+
HEAB$FAIF?B@H@DF?EDDABGEA@?B>?C@D?AF@ICFH?A???@@GEB?AHGACIHFAGIECBH?IAECEA?@CECBF?BFIAFFGHG?GBEFHCHF
@>chr21:9873572-9873697-3
TCAGACGGTAATCAGCCAGACGTCCATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTATGAACCTA
+
IDGB?IDCDGDCBCDDCDDFD@?IAEEEHG?CAICDGA?HHHFCI@IFCF?A?GA@DH@?@DCGDFEIDC?@@?ADA?C?@EHGAGBBFG@C#EEIDBEE
@>chr21:9873572-9873697-4
TCAGACGGTAATCAGACAGACGTCCATCTGATGCTTGATGTCCACTTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTGAACTAGAGCTTAGGAACATA
+
AF@I@?EFIF?EBAEAD@BCDB@DBI@GBIFH@HIAAEIC?@DBF.@EHIBDEBDIFEAHIBEDCEG@?AC@ABEEE?B5DADFC?@@GAIICDBCD:?A
@>chr21:9873572-9873697-5
TCAGACGGTAGTCAGACAGACGTCCATCTGATGCTTGATGTCCACCTTAGTCCTGGGTGTCTACTGGAGACCTCATGTTCAACTAGAGCTTAGGGACCTA
+
EIFH?GB@@G&FD@AE?@GFEG@HADBA?DHD?HEACA@CIHEICHACE@DH@GIIBDGCAIBIGA?DCB?BGHB@HCF?DFDFCAEGFFCE?E<?CFGF
@>chr21:9875228-9875374-0
ACCACTATGTCTGCAGGTGGACACCCAGCGCCCAGAGGGGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATNAGGCCTCAGGTGAACCCAA
+
?@CBHF?CC@B@?FB@@BHDC?GAGGHCHCH@GFCA"FBIDHAH@GHFCIGBBHEFBEHG?@E?BF@FHBEAGIC@??@B:?IH@FFBAFGFAEAHIGDG
@>chr21:9875228-9875374-1
ACCTCTATGTCTGCAAGTGGACACCCAGCGCCCAGATGGGCTTCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCCAA
+
?CC-ABCEFCI@?DI8I?CC@HEEIBEFFEGIFF?IHCD@E8IDHFCF@?H?H?GFDEA??BEEG?FIAHDEIEDD@DFDH?A@BB@E?C?FCD?AFHAI
@>chr21:9875228-9875374-2
ACCACTATGTCTGCAGGTGGACACCCAGCGCCCAGATGGGCATCAGGCCCGATTTGGACATTGAGGCCTCAGGTGGATATCAGGCCTCAGGTGAACCCAA
+
@EFFIF?FD@FAFIEBEIA@GC@C@G?BAI?IDHHEEHFEEFBC?GFDFH-ID@@HAHG@AGFC@CDF5EHGI?EDBH@D@DDGD@H@AEF@?IA@DA?H
@>chr21:9875228-9875374-3
ACCACTATGTCAGCAGTCCATCTGGTGCTTGAGTGTCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTNCACCTGAGGCCTGATATCCACCTGGGG
+
GFE@AEC@@?D?FGAD@@GBC?AFIFGDBDCIFFIE?@@?GFICIH@CA@CEBE?G@FI?C?G?GFBFIGDH0?H?I@FHIAHACGICCA@BCCBGFHBI
@>chr21:9875228-9875374-4
ACCACTATGTCAGCAGTCCATCTGGTGCTTGAGTGTCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCTACCTGGGG
+
DHCHDEGH?CAFCEBICBEDEB?A@IFBAIEH@CGFEDFIGB?D@GICIACH?BH?FCCAAG?DIICAFIGGDCE3BFC@EIII@EBFC*E3@IF?FD?C
@>chr21:9875228-9875374-5
ACCACTATGTCAGCAGTCCATCTGGTGCTTGAGTGTCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGGG
+
GDHGBADCADAHE@CA?GCBFABCG@IHDCFAFF@?DFFDDEBIHHBEEDACC@I?IBH@CIEGI?GCD@?EC?EG?IIAF??FEEGG?BEHADBH@HI?
@>chr21:9875228-9875374-0
CTCATACCACGCTGCAGGTGCACACCCAGCGCCCAGATGGGCATCAGGCCCCATTTGGACATTGAGGCCCCGGGTGGATATCAGGCCTCAGGTGAACCCA
+
@FGBBGHHBCI?EGFAEFAD.D?EF@F?F?GDC@AIFHD@A@IDBIB?DF@GCHCEHI?EIIFF@GBDI@?5ABCEDBA?CIII@EBEHAE?A?HF@H?H
@>chr21:9875228-9875374-1
CTCATACCAAGCTGCAGGTGCCCACCCAGCGCCCAGATGGGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCCA
+
CIAHFD?GB-??BGGHADEF,2C?IFDF?@EABDEBFBEIFBGDC??FEHBCI?AIA@IA??HBBCAFB?BEII'?GH@?@I@DFCDDEA@D???DEHD@
@>chr21:9875228-9875374-2
CTCATACCGCGCTGCAGGTGGACACCCAGCGCCCAGATGGGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCCA
+
E@@AD@D?+DAIHDADIB?E?G?I@C@BEI?FGDGAB@FIEAFHAIDE5DCEDBCFCDDIG@6HB?ABGIDIHDCEBEGCA?CH?HCIFBDAGAB@DGAG
@>chr21:9875228-9875374-3
CTCGTACCACGCAGCAGTCCATCTGGTGCTTGAGTGGCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGG
+
I?E&EB?@@DDCD@?HBHE@IF?DCA?H?HDGEDIGA@FCBB?BEI?F?@G@CF?D?CHAB?BG?DFAHD?IBGH?GHGDAIEAHCCAFFDHHIFICCH@
@>chr21:9875228-9875374-4
CTCATACCACGCAGCAGTCCATCTGGTGCTTGAGTGGCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGG
+
E?CIF?CBACFDHCD@?@HI?CCHB?F?C@@GED@FIBHGBACFCF?GCAEI?BB@BGHCIFG@?@GAAEDFIEHDE?CAFDE?AHB@HHBGCH?AAIGC
@>chr21:9875228-9875374-5
CTCATACCACGCAGCAGTCCATCTGGTGCTTGAGTGGCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGG
+
GFAD?FAIA?AFFDA?C?I@@ACIBDAB?E@HH?GADEFC@I?@GHB?IEBIC@@@DCEH@IGHDF?HBBBDDCICHACEABHBCDCADEFAF@@BACEI
@>chr21:9875228-9875374-0
GAAGGTCCTCTGCAGGTGGACACCCAGCGCCCAGATGGGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGCCGATATCANGCCTCAGGTGAACCCAAG
+
HF@DDFIHDGE@DADBC?CDAACGGIIA@F@IED?GBDGIDECFFD?FACH@GEHAAIE?@EGIHHCIGFAG9)AIAGDDA8FAEFIEE?AHGFGBF#EI
@>chr21:9875228-9875374-1
GAAGGTCCTCTGCAGGTGGACACCCNGCGCCCAGATGGGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGCTGAACCCCAG
+
H@BE@E?AH?FFHDCGEHBCGBAIB-D@AE@?IED??DG?C@IGEDEGHBGDGH@CEE@?@EFBC@GDAHC@??BH@DFE@HDIFGHBA>ABGHFHE&HE
@>chr21:9875228-9875374-2
GAAGGTCCTCTGCAGGTGGACACCCAGCGCCCAGATGGGCATCAGCCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCCAAG
+
IICBB@GCGAFACGD?I?GDFFDFIDDI?IFBIH@AG?CDBEAGG>?IBDI?DCIBE?HCCD?B@IDIEIGHHECEC?DFEIDFEIFIH@GFDGAFCFFA
@>chr21:9875228-9875374-3
GAAGGTCNTCAGCAGTCCATCTGGTGCTTGAGTGTCAACCTGAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGGGC
+
DCECBHG%EAAEG?GFIG@BAHDFHDCAEHHE@A@@FHE?H-CCDHE?D@?EAIAGBB@EBFDHIEB@ACEBB?@D@C?IACBEF@@?F?BFG@FD@GIH
@>chr21:9875228-9875374-4
GAAGGGCCTCAGCAGTCCATCTGGTGCTTGAGTGGCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGGGC
+
A?BHE,DIECBB@DAFCIFEGDFGCIIBDDGFA@FFFCE?DE@E@B?D@FEEBBIIIHAEH?FE@BIG@@GB0)CA@HDCEFDIFDAIHGEEHIAEBICC
@>chr21:9875228-9875374-5
GAAGGTCCTCAGCAGTCCATCTGGTGCTTGAGTGGCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGGGC
+
CCIHD?C?EIIFAIF@EGACGCG?FII??GB@FEHEE?CD@EHHDHD?C?CAIBCCGBIFBIAFEI@EEI@BDBCHE-?FGIHHA?BDECCCII?@H?CH
@>chr21:9875228-9875374-0
GCGGCGTACTGCAGGTGGACACCCAGCGCCCAGATGGGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCCAAGG
+
BHDCIGHBCAHH?EGHGA@HBCH@DECDEBAECIHB?CDEI?EE@?DEDIHCH?AGHF@AEFCFDGEDABEE@DAE@@HBBD?F@IEC@@FDEFIIHEFF
@>chr21:9875228-9875374-1
GGAGCGTACTGCAGGTGGACACCCAGCGCCCAGATGAGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCCAAGG
+
B30CCF@FGAB8HCEAABA?AHF@HHGGDEGA@FBC+D@IHH@@GED?HHEFF@BGGFEDBGDHGDIFIBFIIEGIBBDI@C??FIIAGIAAACGFB?BI
@>chr21:9875228-9875374-2
GCGGCGTACTGCAGGTGGACACCCAGCGCCCAGATGGGCATCAGGCCCCCTTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCCAAGG
+
GGFA@FEHEFBCIBFDIF?GIBAEHF?BEEEGHEECGGB@GEEHIHEBH<FCCHIH@BE@%DDDEB@E?@@@@?BEEFFBAHBDHBF?DE?IAIHHD@EF
@>chr21:9875228-9875374-3
GCGGCGTACAGCAGTCCATCTGGTGCTTGAGTGTCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGGGCC
+
EAAGBDCH?ADFD@AAFDHAE??GFC@B8DIGIFBDBFDH@@IHIH@IICFBDEIEBA@?IFEIHGHBEADB@EH?D?A@@HAHFFFHHEA@HGFH@GFG
@>chr21:9875228-9875374-4
GCGGCGTACAGCAGTCCATCTGGTGCTTGAGTGTCAACNTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCATCTGGGGCC
+
EFIC?EH?F?IBIA@FBCI?HEGGC?IHF@DIIGGD?E,CH@GCHBIIDEHH?EA?ACHD?CC@DAA@HEG?GAIA@A@I?DHIF@AHDAG!@CBF?HAC
@>chr21:9875228-9875374-5
GCGGCGTACAGCAGTCCATCTGGTGCTTGAGTGTCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGGGGCC
+
DIEHABDADIIC@@FABCGEDBBCIBDBHBA?C?HI?CGFADFF@@A@DEC@H@AC@CAB@G?CBECDCCIH?F?GG?GEEBIAFB@AHI@?HE?IGBDC
@>chr21:9875228-9875374-0
TCAGACGGTAATCTGCAGGTGGACACCCAGCGCCCAGATGGGTATCCGNCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCNCTGGTGAACCC
+
?DAEEEGGBHAIBBAGEDC@DHGD?G?C@EFD@I@IICGC?@"IAE'A1?@GC?@?CDGIHHIA@FF?IFBHCIEBDG?@BFGCIIEE<H!EABF@?FEB
@>chr21:9875228-9875374-1
TCAGACGGTAATCTGCAGGTGGACACCCAGCGCCCAGATGCGCATCAGGCCCCATTTGGACATTGTGGCCCCAGGTGGATATTAGGCCTCAGGTGAACCC
+
@HDFED?EAA?GFEHII@@CDD?C?B@FICGCDDA?DACI6CGCAAFFIAI?G?IIHFIFDBICB3F@GEFHFHFICHAGHE#DEABDIFI@F?EAAED?
@>chr21:9875228-9875374-2
TCAGACGGTAANCTGCAGGTGGACACCCAGCGCCCAGATGGGCATCAGGCCCCATTTGGACATTGAGGCCCCAGGTGGATATCAGGCCTCAGGTGAACCC
+
?DADEFAABHE8E@DIDECIICGADF@?GIFCEBC?BIDHGGCGGGFCIHDCGF@EBFFEGEAI??DCCDACF?FABAE@A@??BG?D@?DCCIE?EGCF
@>chr21:9875228-9875374-3
TCAGACGGTAATCAGCAGTCGATCTGGTTCTTGAGTGGCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGATATCCACCTGG
+
CBG?CADFBCGEC@GEDBA@!CBBBIEC3IA?B@@C?@CDDCE?A@A@AFEAGAHHHFGGDCBD@GID@IADA???EE?HGAIEB?BGCE@IBHH@EGHF
@>chr21:9875228-9875374-4
TCAGACGGTAATNAGCAGTCCATCTGCTGCTTGAGTGGCAACCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTCATATCCACCTGG
+
BEIDGHAIBIDA(?GFEA@FB?DDHC(I?DIGFHEHFGCIG?D@A?GAFCBICBDCEEHF?FID?D@DC@CBD?CEGCADGEEAEEH5DFIEGADHBCAC
@>chr21:9875228-9875374-5
TCAGACGGTAATCAGCAGTCCATCTGGTGCTTGAGTGGCAGCCTAAGGCCTGATGTCTATGTTGGACCTTGGGTTCACCTGAGGCCTGANATCCACCTGG
+
IHGCDIA?EBF?AHADIIEFEHFHCFIACF?GHIHFDCFB:@DAIDDD?AGBCHHAA@BHI?ACDDI@DE@ADGEDI?@DDIGB@@EED!CDFGHCG@IG
@>chr21:9880025-9880143-0
ACCACTATGTCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCAAGCTCAGGGGCTGATCGGAAGGTACCTGCATCCGTG
+
HFCCBEBABCCIFIAIHFEDCHBBA@@IHAI?EB@CBG?GHFIDIC@@H?DFG?EDF?H?IHD>FDH!DI@FHBEFF@??@GHACCAFGII:FF?BH@C?
@>chr21:9880025-9880143-1
ACCACTATGTCCGCCCAAGCCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCCAGCACAGGGGCTGATCGGAAGGTACCTTCATCCGTG
+
?AHGGFEE?EH!G?CHAIF,CGAI?@DG@FDIEF??ADEEE@HDB?@HIBBA?@ABEAHD@AB?CIE?@AFAH@BBGCGEBI?IBH*GEFDH@BBDFGIB
@>chr21:9880025-9880143-2
ACCACNATGTCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGATCGCCGGGGCCCAGCACAGTGGCTGATCGGAAGGTACCTTCATCAGTG
+
EACHG+FAEIGC@AADEEIC@HCGABDHBI?AEFHCGCIICEAB@GAI?DC"BGDDD@GBCACEEC1?DII4@FFFIGDGBCDECD??F?DFCAI@.DCF
@>chr21:9880025-9880143-3
ACCACTATGTCAGCTTTGAGAACCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCATG
+
?ID@FEIHECC@DDI@D?H@ED=GFAE?IHCBCBAFIGFCCBDD@EIAHGFD?GFDDCBHI@G?FGFFGI@CFI?FBAGC?GEIFGD??@GAFDCA@?@B
@>chr21:9880025-9880143-4
ACCACTATGTCAGCTTTGAGAAGCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCNGGCGACCCTGGCATCCATG
+
BDCBGCI?H@AGFBFCIB@EDCGE@FFIFBIGEAAH@CAEI??BF@E@FIADHGHEBCAFBDIFEBD@?H@GBDHACHEF=@A?EFIHAG?EIBEIDGDF
@>chr21:9880025-9880143-5
ACCACTATGTCAGCTTTGAGAAGCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGGCCCTGGCATCCATG
+
BH@DBHAE@EAB@?DBCACB?CFID?BIIAC@HI?F?@CFCAIEBEHE@FDAG@?@CGFICBIH@C@HD?EC@BGCF@BE?GEGD.H@BEGAF@GG@EED
@>chr21:9880025-9880143-0
CTCATACCACGCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCCAGCACAGGGGCTGATCGGAAGGTACCTTCATCCGT
+
EBEHIHCDH?@G?@GGFGICIHE@III@BAF?BABCGCIB@HCDHFBFICCAAC@?AIH??BC@?@@CBE@H@EB?I@HAH@CFIIHGIEBGGH?EB@?I
@>chr21:9880025-9880143-1
CTCATACCACGCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCCAGCACAGGGGCTGATCGGAAGCTACCTGAATCCGT
+
G@?CBHEAABCHA?@HCAABEIDHBEF@E@GAIIHBAB?GFC@B?@CGIIFCDHA@?EBCBFIIGIDFI?FCBC?HCICGCFCCAG2BH?DB*!HAD?DE
@>chr21:9880025-9880143-2
CTCATACCACGCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGACAGGGTCGCCGGGGCCCAGCACAGGGGCTGATCGGAAGGTACCTTCATCCGT
+
G?GFH@EB@DHHFABHGEEEH@ICADHBE@BEG?GIHFIC@?FF?DD1GCG?AEAFGA@DGH?ACE?HDEB@?FFG?AGFDHGCAH@H@G@BE@CG?IHA
@>chr21:9880025-9880143-3
CTCATACCACGCAGTTTTGAGAAGCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCAT
+
BEIHAGEC@AHGHF*?EIFFCG?EI?G@CHGGA?GGIE?EFBEH?DHBGFDF?@I@HCFE@ECBG@BHCFBD@DGFHAD@EBEBDGGFCIDHFD?IEADC
@>chr21:9880025-9880143-4
CTCATACCACGCAGCTTTGAGAAGCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCGGATCAGCCGCTGTGCTGGGCCCCGGCGACCCTGGCATCCAT
+
AAGE?GEACFF@GICBHIHEBCAHCBEFCBFEG@GGIHDH@AE?H<?F?HDBI?BHC@3EFC@IBFI5ACBDC@IAG?ICCFGEA?CD@CDAAEFCAI@A
@>chr21:9880025-9880143-5
CTCATACCACGCAGCTTTGAGAAGCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCAT
+
E@IDI?CCHDHGIF?IH@?BAIB@FAB?DCIHFBCCEBEDACFIDF,FBFECBEDCEHFDIBBA?@HHDBHH?CH?EEB?@?A?B?FAGEDFACBEGEFB
@>chr21:9880025-9880143-0
GAAGGTCCTCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCNGGGCCCACCACAGGGGCTGATCGGAAGGTACCTTCATCCGTGG
+
B?FDDIGD@?DIBIHDBCH?HFC?@DCAAFA?F@IBG?H?IEB?DDDAAEGDB@F@/CGAAFA@=CGAFAFEB@FHDBHBGG?GHIHDCHGICDHCBACD
@>chr21:9880025-9880143-1
GCAGGTCCTCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCCAGCACAGGGGCTGATCGGAAGGTACCTTCTTCCGTGG
+
I$DBD@DIEFACH@B@BBGD?@@?FHICE?BIFGHEDIFFD7I?A@EFEGCBC@I@FAGAGHIBEE?HHIHCG?HIAIGCCA@IDB@@DE?G3IDBHIEC
@>chr21:9880025-9880143-2
GAAGGTCCTCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCCAGCACAGGGGCTGATTGGAAGGTACCTTCATCCGTGG
+
?IA@?G?ICIEB?IAAEBEFDG@@BH?EBA?AIDFGAGHF?A?IFHHFB?EIEAEGEGF@?C,AGBDE@GGHCECEDC9IEC@AEC@AI?ICI?GDAHE?
@>chr21:9880025-9880143-3
GAAGGTCCTCAGCTTTGAGAAGCGGGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCAGCCATGG
+
EFD@DFDDAB@?GGI@CHHAE@EDIEBHHFBHI@BD@CI?IFG?@IFBHAHFHCG@FDEH?HACI@ACGDIIAC?DD@HH@B?IH@IE?FG@E*GE@CB?
@>chr21:9880025-9880143-4
GAAGGTCCTCAGCTTTGAGAAGCGGGGCCTGGATACACACGGATGAAGGTACCTTCCGACCAGCCTCTGTGCTGGGCCCCGGCGACCCTGTCATCCATGG
+
IBI@IFI@CHICGHCGA@FD?FDHG@HFACBH$@EG;GHEHA@B?I@G?EH??FFCAC@*EB@HH(HECCC@@HDGDGBACCDD@EHCEG9EFDFDIDIF
@>chr21:9880025-9880143-5
GAAGGTCCTCAGCTTTGAGAAGCGGGGCCTGGGTACCCACGGATGAAGGTACCTTCCTATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCATGG
+
GCCGGGDGCDFFC@E?@EGIG@GFDF@CDCCCCAIG?ADFBABHBGHIBFBIHB@@E/BEFC??AA?DIDFIFHBCEDCB?EIIABGF@@IFAECG@@FH
@>chr21:9880025-9880143-0
GCGGCGTACAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCCAGCACAGGGGCTGATCGGGAGGTACCTTCATCCGTGGG
+
DDCIHDBGIBGFAIGA?GD@IFDEGA@ED?IFFD@A?II@CAEBD?I?@GGFFFGCEFBE?ADFFG)D?IBGFHAFEBCI#FDCE@EEFIEBBDHF7D?F
@>chr21:9880025-9880143-1
GCGGCGTACAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCGGGGCCCAGCACAGGGGCTGATCGGAAGGTACCTTCATCCGTGGG
+
HHIBE?BHG?FABEHEFD?CIICC@D@@BCAIGF?GDDIDFAAC?I@EEEGE?IDGHBB@CEBIBI?GHAIFBIF@??@HCIF@?A?HDECHE@AHIG?A
@>chr21:9880025-9880143-2
GCGGCGTACAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCTGGGTCGCCGGGACCCAGCACAGGGGCTGATCGGAAGGTAACTTCATCCGTGGG
+
@?IF?GIHAF?BFBCBEIABECCF@HCA@C?IGDI@BCC?B@GB@?(HHACIA?ED@@:D?HFEAGED@FCFGCHHGDCGCCGFBH;EBGID;?GHADHE
@>chr21:9880025-9880143-3
GCGGCGTACAGNTTTGAGAAGCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTTGCATCCNTGGT
+
FEF@HHEI@IA7D@CB?HAH?@FDI@CHCI?EGB@FHEIE?DC?@C@EEBCH?CCHBA@EIIFGE?GDIDFG@C?AFEHIGE@E@BCE:DBIDFH3?CDF
@>chr21:9880025-9880143-4
GCGGCGTACAGCTTTGAGAAGCGTGGCCTGGGTACCCACGCATGAAGGTANCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCATGGT
+
IIFD?CCBB@@IGGDDB?ICBEHIGIHECAEADDEHFBAB+EC@ABE?A?9@A@GC??@HIFCD?E???EF@ABB@BDDEBIEBGEDAIDFFAIFHBDCH
@>chr21:9880025-9880143-5
GCGGCGTACAGCTTTGAGAAGCGTGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCATGGT
+
DAB@DFGCHBGCIFIABH@EDGAGDGF@AHEGGAAGBGHEIGHI@DDICCCC?HAFAFGG@@@ICEDFHDIDEH?I?HAHECIDGBDFCBIHEGDG@CBF
@>chr21:9880025-9880143-0
TCAGACGGTAATCAGCCCAAGGCGCTCCCTGGACNCGAACCATGGATGCCAGGGTCCCCGGGGCCCTGCACAGGGGCTGATCGGAAGGTACCTTCATCCG
+
EBBDAF@G@EICGHDDBIGDDGIICIF@ABGHEE3AFDDAA?D@ICF?EEFH?IBC3EBAEAEBHD0F@I@HDH??GBAFC?@G@BEDG@DDGACIHCAD
@>chr21:9880025-9880143-1
TCAGACGGTAATCAGCCCAAGGCGCTCCCTGGACTCGAACCATGGATGCCAGGGTCGCCAGGGCCCAGCACAGGGGCTGATCGGAAGGTACCTTCATCCG
+
FBAI?IGG?CABCEDCDHFHID?H?GGCEAEIICBBEGA?E?DDGICCDDAGCBDHBGH/FD?HGCF?D@BHAACGD@F?CI?EBIBHABIEDBDCEDB@
@>chr21:9880025-9880143-2
TCTGACGGTAATCAGCCCAAGGCGCTCCCTGGACTTGAACCATGGATGCCAGGGTCGCCGGAGCCCAGCACAGGGGCTGATCGGAAGGTACCTTCATCCG
+
DB*?FBGBDF???CGGIAHFIGCHD?HHDAB@BAB$AGDAG@FCCIGFHHEGEI@C@E?EA<FDEAG?AIGIFFHC@ICGHHAG?@DF@GEHHBHICFBF
@>chr21:9880025-9880143-3
TCAGACGGTAATCAGCTTTGAGAAGCGGGGCCTGGGTACCCACGGATGAAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCA
+
HHAAH??HHCFHCF?HDCFDII?FFACHCDCHABE@GCFBGIGIDA?FFBIEGB??@FC@HEB?IGABAHFEHI@FB?ED@IFDEHH@GHG@FHAFEGHE
@>chr21:9880025-9880143-4
TCAGACGGTATTCAGCTTTGAGAAGCGGGGCCTGGGTACCCACGGATGAAGGTACCTTCAGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCA
+
IICIHGHAE?5EICAA@CIAHHBD?@A@E??EH)CE@B@EFHEDACIHG@E@C?BEBIB$DBE@E@EB@GFABH?CCF@?IHHDGFIF@GHHGHDA?AAC
@>chr21:9880025-9880143-5
TCAGACGGTAATCGGCTTTGAGAAGCGGGGCCTGGGTACCCACGGATGGAGGTACCTTCCGATCAGCCCCTGTGCTGGGCCCCGGCGACCCTGGCATCCA
+
@@I@@F?G@G??B-EBD?DHBDA@C?DBD@E?BBFCHGE@I@BIGHIC'@GB@?D?ABBCEBCFIGHDEBDADCHGEEE@ACCHCE@DC@HEEDHHAAHI
@>chr21:9882076-9882225-0
ACCACTATGTCTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCGCCTCTGCACACACTTCGGAGATACAGCAAAGGCGG
+
ACAFBCE@B?GED@E@FCHDBECHFDGBGHII?B?B?HFDIHGIG@HIEIEHEHB@EBH@;DAE4?B?IIICEFICAGBG@CI?CGFIBFA?@F?ACIBI
@>chr21:9882076-9882225-1
ACCACTATGTCTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCGT
+
DBFDEFBGAEEBFBAHBADGGC?@DEHEBI??IGICB@@GF?ACC?HBEDG??AIBBHDGIAH??)FCD?EF?@@H@??IAGFBGFED@EHG@IBHGFH=
@>chr21:9882076-9882225-2
ACCACTATGTCTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACCTCGGAGATACAGCATAGGCGG
+
@ICG?F@F?EII??DHGEDCFCCDGF?C@FAA@D@IED?DG?@H@ACBBIFA@CE?IAAC@BFF?FDDFB@FFEDADA+FA@@E@CBAG?CE8<HE?D@E
@>chr21:9882076-9882225-3
ACCACTATGTCAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCNCCGAAGTGTGAGTA
+
IAEDFAIADF@IEDIIE@DE??@AHBDEEE?DDICHHI@D@EDCCHHDF?BIA?DAGA?E?@IBB@AA?DFCIHHG?B?@BFB@E#AHECB?GBFE&@6?
@>chr21:9882076-9882225-4
ACCACTATGTCAGCTCCACCCTCACGAAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTNCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGCA
+
EBGIFBIH@GCEDDIEB!BG@IE@I@HCECF@DIB@BFGB?E@@E?D?HBII?HABCGFCIHAF?A'???C?FEEFH?AAE@AGIDAEFA@@EDHDH?@H
@>chr21:9882076-9882225-5
ACCACTATGTCAGCTCCGCCCTCACGAAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGAGTGCA
+
ICBHBG?GBH@HH?HIFEEFFIIAI@@CDDDIIIEF?IHE@GFAD?ABDBFH@B??FHDCGHCFD@CHIIFE@IBCHBEDBAF?GAC@B@ACAF'IA?D?
@>chr21:9882076-9882225-0
CTCATACCACGCTGCGTTCTTCCCAGCACCGACACGGAGAGCATAGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCG
+
BDBBACGAIIGDGFBDHBF;EHAHCAA2BB@@IHDDACIGBGIE6EBA?@FFCI@CABHHAACAC@?FBCC?2GFI?@@AF@EDBDEGIEGGEEFIHI?B
@>chr21:9882076-9882225-1
CTCATANCACGCTGCGTTCTTCCCAGCACCGACAGGGAGGGCATCGACGGCGCGGAGCTGAGTTCTCCTCTGCACTCACTTCGGAGATACAGCAAAGGCG
+
EGAH@F5HAC@@?CG?HCFFB@H??CFIHEBE??8BCFC3EI?FDA4HDA-DDDHCHBFE??FAIBGFHHFAE?@/BH?BHACAFDAAG?EFC@CAD@I?
@>chr21:9882076-9882225-2
CTCATACCACGCTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTCAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCG
+
BIGHEAEAC@AE1@??AFAHCBBCCEBIEAACBE.BIAIF@EFIGEFGEDCGH@@G@EE+F?<EFIFBE?BDA?E?IB?CBECHCH?HAI?GC?B?ACCH
@>chr21:9882076-9882225-3
CTCATANCACGCAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGATGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGC
+
EI?AFC.A?CCCEHA@CFDD?B?CEBBAFH@GDIHIB?BEGADI?DBCIG@CI,AF@BICGBB?EHD?@GE1A?CAHDH@C?GDGHFCHBFIADHGGF?@
@>chr21:9882076-9882225-4
CTCATACCACGCAGCTCCGCCCTCACGGAGACTCCGGCNTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGC
+
GAGA?G@AECCEBHCAIGICEFBGH@DGIIDA-IBAF@'EGCHCDDFCGBGEIHFEGGDICEF@GHIAHFB@ACFFBIFAD@IAIAIIGHICECADFEI@
@>chr21:9882076-9882225-5
NTCATACCACGCAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGC
+
$IGHFHADA@IB@DAHBBC@DG?IC?GECAEGGFBIC@?DHDIG@IHBDFFEHG?GFCH@@HA@DDHDIIGE@?D?@FHEIGCBBGA@C?AHEHD?A@BD
@>chr21:9882076-9882225-0
GAAGGTCCTCTGCCTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCGGCACACACTTCGGAGATATAGCAAAGGCGGA
+
E?CHCEG@BD?I?&I?@?BHA@DDDGDHCGC?GHHCEEBF?AGDE?EAHAECDEADDGEAGH@BD@BA2@CHDBIEHD@G@E@G@DD2G?GA@AIICB??
@>chr21:9882076-9882225-1
CAAGGTCCTCTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCGGA
+
-GE&H?HDEDICGIDCCGCAF?HFB@GC?E?BDDDHEF?F@FB@F@F@FIGF?FB@D.GG@EEG?BFFHHHBA?CEC?@HFE@D??GHCDFG?DFGE@EA
@>chr21:9882076-9882225-2
GAAGGTCCTCTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCGGA
+
?E?GBECGH;D@@@DEBB@FBAB@B@BGCDHECAHAFEBF@FCDIBBEIBFDHCF?H?A(B?HEIAHBC@F@DGDBCCDBBGHDHA@???F?AGIIICBG
@>chr21:9882076-9882225-3
GAAGGTCCTCAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTTCTGTATCTCCGAAGTGTGTGCAG
+
EI?GFGBE?IGACGI@ADCE@B@IE?HBB@DH?G?B@DEB@IBEHADCII@AGB@HAFCED@H??IB@EDIGI@HI#DHEICBFGBBACIBEHIGEBHED
@>chr21:9882076-9882225-4
GAAGGTCCTCAGCTCCGCCCTCACGAAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGACCACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGCAG
+
BFIGC@EE@GHEH@BBCAEIHBADHDGC?BC@DAGGE@GFE?DEDHAFFHCCAFEE@DHB*DCAEFC@CEABIB@AFHGEH@??GIFAEGIDDDFB@DEH
@>chr21:9882076-9882225-5
GTAGGTCCTCAGCTCCGCCCTCACGAAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGCAG
+
E6@D@GBGH@E@IDDF?G@HCDHIAH@G@DGHDIDHCD@HF@CEAHGCABCIDCBCBE?GDDADF?EDH@GDD?@ABGGAFAII?DHDBE??@GGIBAGB
@>chr21:9882076-9882225-0
TCGGCGTACTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGTGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCGGAG
+
6DD@IGIF@CADH?EFEAHDCBDCFFHDFIDGGD@HB@D@EDFDFIBB?I*DG?FDC*B<IDGC?HCB@?C@CHFA@CGCAFHICDCGAB@??ED@@BAG
@>chr21:9882076-9882225-1
GCGGCGTACTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCGGAG
+
IBAEIBIEBHII?HGDBH@IHEID?BBB?HA@@IE@IG@I@G?ICA?ACD?@GAEEC?@@G@@DGI?ICFDI?HGCDCHFCGCHDI@I?G?AIFEE@III
@>chr21:9882076-9882225-2
GCGGCGTACTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGTAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGCGGAG
+
ABGEG?GBEBIDDFADFCHEADH@@DHA@DGFH@CCF?IBBCHADFI@FBI7C@I@FHHGGGDEECFGF@DHCI@?DICIE?CDDEGI?FHDGEBE@IGD
@>chr21:9882076-9882225-3
GCGGCGTACAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGTTGTGGAGAACACTGCTTCGCCTTTGCTGTATCTCCGAAGTGTNTGCAGA
+
AGACABE@FGHEDABB@I?GGFFEHIID@HEDGDCCHIBCBEDDCHGD?HFHF6HFF@FF@I?GEBH'GFCGI?FA?ECGAA?HHICEHD?CE7HD@IAD
@>chr21:9882076-9882225-4
GCGGCGTACAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGCAGA
+
CB@?=EEICGCEAC?E@BC@AF@F@EHGGEEIFBF@GHAAEDECF?HFHGGIIEAHEEADIDHCEAGHIEEDEEC@GAB?@G@@DBCIFIDDEIFA@GED
@>chr21:9882076-9882225-5
GCTGCGTACAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTGCAGA
+
CC7FDB@DGCEFADAAB@BFIA@H?AAG?HBBEDDDGHBHBB@@7DIAIH?H?CDBEFHDGGAI?GFIEA??HHEIGICAHD??@FFFG@DDF??CCEGA
@>chr21:9882076-9882225-0
TCAGACGGTAATCTGCGTTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGC
+
?AFBDHCADIID@EGHGAAFGAGH?CECBH?@?IF@FFFFAB?EGBIC?IG@BGH@GDGD?AHGAC?B@?A?E?H@IBGAI@B?CEFBGGG?FF?I?CCG
@>chr21:9882076-9882225-1
TCAGACGGTAATCTGCATTCTTCCCAGCACCGACACGGAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTGCACACACTTCGGAGATACAGCAAAGGC
+
IEEIHI?B?@DC@BBF/HDGGFGFHAIHEH@FBEDAAA?I?GHE?AEH?FC@DAGDDEHGFGE?BG@?CD@?ACICGBIFHE@IBA@FDHICE?AFEFFD
@>chr21:9882076-9882225-2
TCAGACGGTAATCTGCGTTCTTCCCAGAACCGACACGNAGAGCATCGCCGGGGCGGAGCTGAGTTCTCCTCTTCACACACTTCGGAGATACAGCAAAGGC
+
IDEIIFFD@CAGAEBECE@?BIFBI@?:CGCAHEEDF8C?D?BEF@@@DDB@@IGDD?@BED?AHAFHD@GH1?CFFC?BACEEDIBHCBGAIIGHCHFB
@>chr21:9882076-9882225-3
TGAGACGGTAATCAGCTCCGCCCTCACGGAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGAG
+
A2B?IDEIEDHBHBHEEIIA'@?AID??A?GCEBHG@@GIGD?I?@FAA@CEE?A@?EEACGHFBCBHBIFHFDH@BBHID?FHGDBIBBGBDBI?G?3D
@>chr21:9882076-9882225-4
TCAGATGGTAATCAGCTCCGCCCTCACGAAGACCCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACACTGCTCCGCCTTTGCTGTATCTCCGAAGTGTGTG
+
IEHID.GIAEIIFIACHE@IEAGCG#BHGICDBE@HHEFBD?@IECFBFG@IHHIEDDDCBHG?GFHGF?DIBDABECG?BEBCGFGFG?HBB?@CIID@
@>chr21:9882076-9882225-5
TCAGACGGTAATCAGCTCCGCCCTCAGGAAGACGCCGGCCTGCCCAGGTCTGTGTTGAGGAGAACANTGCTCCGCCTTTGCTGAATCTCCGAAGTGTGTG
+
CFDA@ADDHCAAIFBGACHAACEI??1?BCIFE&DGBGBG?ICBB?CD@?BAB@D?GGF@BBBCHH"@EBFDB@FEBHIEHEG"HHIDFD?HGIA@ICDG
@>chr21:9882222-9882363-0
ACCACTATGTCTGCGTTCTGCTCAGCACAGACNCGGGGGACACCGCGAAGGCAGAGTAGCGATCTCCTCAGCACAGACCTTGGGGGCACTGCCTCGCTTT
+
HBABFDGHFGCB?FFIAHIDBDC?FEHDD?CI0AI?B@CAFA@IBHC@EAII?IA@?DC@EIHG@AC?IA?C@FD??D?HDFAFBEAFHICGAI?B?FH?
@>chr21:9882222-9882363-1
ACCACTATGTCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGTTCTCCTCAGCACAGACCTTGGGGGCACTGCCTCGCTTT
+
FDDEH?GEIED??CI@BCBB?HDGICEHGFBCICGGDDAGCBEAEHG@HDBDHHHDAHE?CBIC@AEGFFGAHHCIEAGFAH@HDIFB@GIC@CID@B?I
@>chr21:9882222-9882363-2
ACCACTATGTCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGTTCTCCTCAGCACAGACCTAGGGGGCACTGCCCCGCTTT
+
BBDG?AGEEB@BABHAB?@??GEB@CCFFCGDAHDAD?@GFAFFHG?HF@EHB?I?ACB@@@IB@?BF@BG?IDCBH??D#BAADEA@HCDCD!G@HCHI
@>chr21:9882222-9882363-3
ACCACTATGTCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCGCAAGGTCTGTGCTGAGGAGAA
+
DH@CA?EHDEHACDAFHHBIDFFBDBFDFGAE@ICAIEFAIECHDBGCEEIB?CDFAADIG?BFI?EEIB??HICH@C"ABGE?DDEEBGIIHIF??FHH
@>chr21:9882222-9882363-4
NCCACTATGTCNGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTTGCCCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTGCGGAGAT
+
,EG@BC@@F@E,@1BIAGAGC?HFICIAGA@B@EF?CEHAGHF@?HI@BED@HBAH?3AHH?BBFEIGHBDCICGGAFHGFHBF??G?EAGHA#??I@IE
@>chr21:9882222-9882363-5
ACCACTATGTCTGCAAACAGGAAGGATTTTATTCAGAGACTATGCGGNCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAGGAGAT
+
IGEBGEGGEDCEHED@@BBCFGFHCH?GDH@CEDEA5H7GF@II@@?(CG@CG@DDI?F*GGIADBGFFGA?IIFA?GB@ABB@@C@BD?EDIIAEHHBA
@>chr21:9882222-9882363-0
CTCATACCACGCTGCGTTCTGCTTAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGTTCTCCTCTGCACAGACCTTGGGGGCACTGCCTCGCGT
+
CBIGDBHEDFAFB?B@FGAC?@G;GGC@DA??@@AF?ICBGIA@GABHEABIDCF?AECEIE?AG@HDDA2A?BDDHCCI@HDHBFB??A?IIGCFCF2H
@>chr21:9882222-9882363-1
CTCATACCACGCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGTTCTCCTCAGCACAGACCTCGGGGGCGCTGCCTCGCTT
+
CDF@@@IGECIIDDBFC?A@HFCBFD??H?BDEH@BH?E?I?F@HBAEEBIGC@FAHFHH7BC@?FIFEA?CHDHIE@EDB:EDBHCE/?CABBDFDGHD
@>chr21:9882222-9882363-2
CTCATACCACGCTGCGTTCTGCTCAGCACAGACCCGGGGGACNCCGCGAAGGCAGAGTGGCGTTCTCCTCAGCACAGACCTTGGGGGCACTGCCTCGCTT
+
EDIEEBEAAG@FH@CCF@?E@CHGF@DDAIG?FGEEII?HBG*EAIECGBBEIFAHB?4AHH@?AHHAHIDGCCG@G?@@ADCCIGE?IAABDAD@EEEH
@>chr21:9882222-9882363-3
CTCATACCACGCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCNGGTTGTCCCNAAGCGAGGTAGTGCCCCCAAGGTCTGTGCTGAGGAGA
+
FD?@EHBH@E?EEEICGDGD@??EHEF@FDDFA@HBDG@CIEIEGBDBDBFF.6GAGAEF?H+DCIHEFGG*@E@GF@HI?ABIHBECBHD6BEE?CGEI
@>chr21:9882222-9882363-4
CTCATACCACGCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTTGTCCCAANGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAGGAGA
+
?@BA@GGHADCDDAE@@I?BBCG@@HGAEA?EI@BH@AG@D@GFFAGH?F???DEBDFBDBEHC-GFHICEEIAGBGGEBH?@@I@HECADACEEFF%?D
@>chr21:9882222-9882363-5
CTNATACCACGCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCTGCCCCGAGTTGTCCCAAAGCGTGACAGTGCCCCCAAGGTCTGTGCTGAGGAGA
+
DD,HBI@EFFBGBFCBE@FEG@@IAAEBHCDHIE@CI@FI?EFEEB4@H@CIAHCAIGD@@AFHFDGD9G8BBI@BFCBC@HGAIC?IHBAICI?II?AD
@>chr21:9882222-9882363-0
GAAGGTCCTCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGNAGCGTAGCGATCTCCTCAGCACAGACCTTGGGGGCACTGCCTCGCTTTG
+
GCE@?EHF?HBE@GHGG??IHEFEF?FFC@GG?BI@GEDAH?ECFAGAIC;DI+G?BDGGFHBCEB?IFEBD?BHFCDCH@IIG?CEICBI@AIIBCAGE
@>chr21:9882222-9882363-1
GAAGGTCCTCTGCGTTCTGCTCAGCACTGACCCGGGGGACACCGCGAAGGCAGAGTAGCGTTCTCCTCAGCACAGACCTTGGGGGCACTGCCTCGCTTTG
+
EAFEIBIDA@HFA"I?FD?IEBHIB@D4ECGGBGDCGGBE?I?HA?HA@1AB@II@B@BE@BBFHHEDDAA@FFI??GG?@BF@E@IF@GGECB?@B?FD
@>chr21:9882222-9882363-2
GAAGGTCCTCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGTTCTCCTCAGCACAGACCTTGCGGGCACTGCCTCGCTTTG
+
FGB@DFBAHC:EAGIHC?G?FBABA@CD@?EEGEIA?@@HCHCACGACIGDIACDI?BBGAGAGDBGE@ECB@HAHH?@HD"H@?AGAHAD?AA@FBHAB
@>chr21:9882222-9882363-3
GAAGGTCCTCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAGGGGAAC
+
@F@?BIACDDFI?HEEAHEH9I@GEBDHFBF@IBBEF?CIGHHB@CBFDA@IDACD?@ADCHFG?@B?GCFDHB@GEACE?BEGIADFAGFGBFB&CBCH
@>chr21:9882222-9882363-4
GAAGGTCCTCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGGTGTCCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTTAGTAGATC
+
IFGEGGBAGGDD@EACBEBEBF?CD?HHI?FG?@BFIHCAAH@C?BFAEDH@E!HBEDBF!@DDB@HGCCEFHEGHFD@@?ECEFG?IAGI.EH!GH@CA
@>chr21:9882222-9882363-5
GAAGGTCCTCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTTGTCCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAGGNGATC
+
BED?DGABHF?G?HD@DAH@HAGGHF?@ABHFDCHABHDDBI?G?DAADBIIHDDAHEBFCEBECF@HIBB?AG@EFI@A?DIDH???@IH?CE?:@AHI
@>chr21:9882222-9882363-0
GCGGCGTACTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGCAGCGATCTCCTCAGCACAGACCTTGGGGGCACTGCCTCCCTTTGG
+
EF?IBDDFHCICFABHGAEBDHGHAG?GD?FAA@FD?GDIDCBIFFFBFAIII?!CCGFFC@AA@AG@EDG@BFGCFDAICCFHGFBHCICH@.FHC?H@
@>chr21:9882222-9882363-1
GCGGCGTACTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGATCTCCTCAGCACAGACCTTGGGGGCACTGGCTCGCTTTGG
+
CDC?HGIIHAIABC@IGBCA@FBCAEHD@ECHGE@FC?CHH?CB?H?@DA@EEDG?GE?EBIDG?BG?CGCI?EHGIF?IGHIIFDCGC+??CI?@I@?D
@>chr21:9882222-9882363-2
GCGGCGTACTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGCAGGCAGAGTAGCGATCTCCTCAGCACAGACCTTGGGGGCACTGCCTCGCTTTGG
+
IBHCED@?IG?H?B@BGD@EDGCICHE?DFBEAADI@GCGDBBCE7AD?BHEGG?G@EGFEIFEHBIAIBEGHAGBHCGE@DIH?IAA?D@EEDFHDHC@
@>chr21:9882222-9882363-3
GCGGCGTACTGCAAACGGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTNGTCCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAGGAGATCG
+
D?IHDDEGEGFFG?IC;IID@BFCECIBADGFB@ECEAB@EGH@?IG@BEFII0ADGICI?D@B@FAGEHBBAHCDGFGI@ICA?D@GIAH@IADADFB?
@>chr21:9882222-9882363-4
GCGGCGTACTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTTGTCCCAAAGCGAGGCATTGCCCCCAAGGTCTGTGCTGAGGAGATCG
+
I@HIEBCBIHCGCDGHEFEIFF@@ABA?BBFIB@IHCHBIGDEACCAAHIHF@AA@GID?CCF?E@FAFG5?IBH?FCCAIH??DAHII?FGIHCIBBEE
@>chr21:9882222-9882363-5
GCGGCGTACTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCACCGAGTTGGCCCAAAGCGAGGCAGTGCCCCTAAGGTCTGTGCTGAGGAGATCG
+
AAG@CHBCDCBBECDGDIG?I@AGFB?H'BAA@@EC?HAGEC@?@H;G?@?G?E@"GFGB@GAFHF?CGCI@@GCBA'?@FBBHFDC@FCFAGBAH??DB
@>chr21:9882222-9882363-0
GCAGACGGTAATCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGATCTCCTCAGCACAGACCTTGGGGGCACTGCCTCGCT
+
-HGFDF@EGGHIHI?@@EHFIEHDIAB?H????GDCA@ABBCAE@F?@BCBBHAEAIFAH@DDAGB?DDBHE9FBCDCBGEAFDIIHFH?EBDICAGII@
@>chr21:9882222-9882363-1
TCAGACGGTAATCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGAGATCTCCTCAGCACAGACCTTGGGGGCACTTCCTCGCT
+
?DEGEACAGEHG@C@AIBGHGCD@HDBDFHDCI-?DEIIAFABIGDFFI?DBDDACHC?B@6E??A@IIBG?F@@HIBI@DACIECBGDHDG*FGEBBCE
@>chr21:9882222-9882363-2
TCAGACGGTAATCTGCGTTCTGCTCAGCACAGACCCGGGGGACACCGCGAAGGCAGAGTAGCGATCTCCTCAGCACNGACCTTGGGGGCACTGCCTCGCT
+
GIBB@DGCAGFFIIGABGGF?EACGCA?G@GCEIE@EG??A@EDDGFF,@G@?DCBGIGDDIGH@G@IB@DDDAAE)GEDEBGDC?BEGH@IGEIAA@BC
@>chr21:9882222-9882363-3
TCAGACGGTAATCTGCAAACAGGAAGGATTTTATTGAGCGTCTCTGCGGCCCCGAGATGTNCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAGGAG
+
CFIGBEDFH@@BACAGCEDGF?HAE?DHFE@EF@F4IDDD@DE9BDBGG?GHAEBC=D?C%BCGIEG$G?@DAIHDFF@F?AD?FIHGGBGAHFGCE@FA
@>chr21:9882222-9882363-4
TCAGCCGGTAATCTGCAAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGTTGTCCCAANGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAAGAG
+
IGGE"B?BGABGBDHBIDGBHCGID@BFGIACF@F?HCAD?@?EGBFHFEGCDAFIB??ICIF@B3IEBCBBGDHGIEFHIEDH?EIFCFIAF?CI"CG@
@>chr21:9882222-9882363-5
TCAGACGGTAATCTGCGAACAGGAAGGATTTTATTCAGCGTCTATGCGGCCCCGAGGTGTCCCAAAGCGAGGCAGTGCCCCCAAGGTCTGTGCTGAGGAG
+
HFCD???DHGAIDEB@:HIDBDAFHGC?GI?HGFHC?BCG?DEBEIGCCFFAH?CD+?GAAGIDEBGHEIG?ADEFBDACBI?C@A?IFIFCDIGDG@GD
@>chr21:9882360-9882499-0
ACCACTATGTCGGCCCTGAGTAATCAGGGTCAGCGACCNGTAAGAAGGGTTCTGTGTGGATAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGNG
+
HAAEAB?H@H@<@CEAFICBF?FACG?CBBA?F@@CBD7@HFID@DBH?CEI%ACFFD@B>C???GBIADD@AEIB@IIBD@GCDH@D?BGHB??CHF$C
@>chr21:9882360-9882499-1
ACCACTATGTCAGCCCTGAGTAATCACGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGAG
+
G@F?GGGCIIBEHGFEAD@5AI@HCC4FAFAIABHCAEIBD?FCB@CFH??DAIDHBGIHBE@@G@EHFFDAAEIIBE?C@IGCD?@I?ECE@C@FABE@
@>chr21:9882360-9882499-2
ACCACTATGTCAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAANGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGAG
+
AA@EFA@EDEABBAIGBA@?DCFA?HEBBHCCHHEF?BAC?@CF?CEBGIFFDHGCAHAAB?$IF?DCABCGBHHEFHEFE@FBIEAHE@?HGAGGEDAH
@>chr21:9882360-9882499-3
TCNACTATGTCTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTTT
+
7A6DHFICIDBCAFEAIABIGGH@EA@FHHECEDGGAC?G?HFAAAAEBBGCEHFCHDEBGAIBICDE@IH@ABCBHAHGABCCE@FIHHCDAAAAAHF@
@>chr21:9882360-9882499-4
ACCACTATGTCTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTTAGAGGGGCTTTTGGTTTCCCTTTT
+
?EBAIAABHG@GCDE@@DGH?DDBBIGCA@DDFGEBF@G?CDEGEIB?ADDC@G@AGHAECBCDCDH?GGIFIB@"D?@@GIAGGFGDGHAEAEBHGAED
@>chr21:9882360-9882499-5
ACCACTATGTCTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCCGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTTT
+
ECFEEA@EBBFGGBHECGBI?IH??@?@B@DIIBD@HHAHICCFCIF@@AAA@B@GD?IFHI:G@CABECFGEGF?@?AAADF@CIGHFHFBH?CGBFAA
@>chr21:9882360-9882499-0
CTCATACCACGCAGCCCTGAGTAATCAGGGNCAGCGACCAGTAAGATGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTTTGAATCCTACCCACCGA
+
CI@A@A@I@AHIEHIIHGGD@AACIDFFC?$DI@D???@BBCCABG5C?IB?HHAIAAEAI@IDH@?FCADHGHDGCICFBC+BD?BDC??FFGBEDFCG
@>chr21:9882360-9882499-1
GTCATACCACGCAGCCCTGAGTAATCAGGGTCAGCGACCAGTTAGAAGGGTTCANTGTGGAAAAGGGAAACCAAAAGCCCCTCNGAATCCTACCCACCGA
+
;BEIH@DGAB?CBEACIBDGA@A?AACCIGG@CAACB@CC@I$IA@@FCECDF?22??FAFBE?CG@@IGC@HDBCFI?@??@<DGAC@EGFCI%BCIBI
@>chr21:9882360-9882499-2
CTCATACCACGCAGCCCTGAGCAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGA
+
IHFIDIEIH?@B@GGC?EI@A4AEDEIBAGBDG?EFBGIDFF?DE?BIGAECIB?CBG?ADG@DAGCG?@IB@HFCAG@BIIH?DC@F?EEG@BC?FDEF
@>chr21:9882360-9882499-3
CTCATACCACGCTGCGGTGTGGATCTCGCACTGCGGCGCCTCNCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTT
+
BCEEICGBCAGBCH?CG@H?GEIDGEEHHDC@@EAI@?GBHE'AD?GDIF@IFC?HGDFEHG@E?@IDE@AGFEHFEF?CF@EFFDH@@A@HGBED@C?E
@>chr21:9882360-9882499-4
CTCATACCACGCTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTT
+
CFFD?@BIF@DECDBHF@GID@DIHFFEAEEC?AGB@HI@H@IIIICFCAF?FAEFBIBBEGIDDIBE?HFA@HBC@>AHFC@FAFE?AII@FFGBHGF?
@>chr21:9882360-9882499-5
CTCATACCACGCTGCGGAGTGGATCTCGCACTGCGGCNCCTCACCTTGGCTGGGGATAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTT
+
IFE@ACIAEG?@GHBFEHCFBE@CHDFF@I?@?A?@?&IG@D4FCEIIFC?FDA?F7@4@BHHAAICG?HCBCGEAI?A?G@HFEDC@IE?HF@IGIIB@
@>chr21:9882360-9882499-0
GAACGTCCTCAGCCCTGAGTGATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGNGA
+
BF?4DD?@?CGGGEAHIEHF:HCAEG?IA??ICAEICEC?HDEGBFFFI@?@?DGIIAG@BDDID?C@@EHC@@I?IIH@EEDCDCGDIC?GFDFB?,A!
@>chr21:9882360-9882499-1
GAAGGTCCTCAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGAGG
+
HG??@C?EEEIFEGECFAI@A?CDIIGEDHFIBFEIBFC?EH'AH?FHEGBDGHGAHA@BGCIFFE@@AIFA@DFAB4@EH@FG?HGGCE???BC@BBB@
@>chr21:9882360-9882499-2
GAAGGTCCTCAGCCCTGAGTAATCAGGGTCAGCGACCAGTAATAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGAGG
+
H@FACAGC?D@CGAIBGDF?CABB@BAHAICHA?GCACDCI@>@@@EB?IF@HGE?AE?EFHBA?@FAEGFFIF@HCBAH?D@GGGEFIBIFIAA?A?@C
@>chr21:9882360-9882499-3
GAAGGTCCTCTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCGGTGNGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTC
+
?FACGAHECIHEDB?AI@BECB%BIAAABGA?FDFEFFHIFDDFIIA?CEHA@@?EFCB@IGDEF.GFA?FFBIEA@HC?IEIEGIGECIIGBEA@BC?G
@>chr21:9882360-9882499-4
GAAGGNCCTCTGAGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACGTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTC
+
C@E??6F@?DFF)EIIBHFHHFF@??HEBGCEH?IAEC@FGB)@HHAHFFCD?C?HGG,HGGG@DC@BGFAIDBEHBAAIDBF@E?@AGHEGBBAFFFGB
@>chr21:9882360-9882499-5
GAAGGTCCTCTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCGCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTGCCCTTTTC
+
HBDHFCC@CEA@DHHBCI@D?CG@E?GC?G?BBB@?@GHBFGBG?BBFIGDGAHFBFH?6AEHECBIHF@ECB?F@DCF?I@DCIHGA@?F"AH?A@HDB
@>chr21:9882360-9882499-0
GCGGCGTACAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGCAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGAGGT
+
IIHCEFG?GHDD@GC@DB@BFHFIAEAHIHIFC@FCA?DGIDICGAABF@FB?CAC=??FFIHDEDFBEGBBBG?BFBB@@?H?EAE@@GBFIBFIDHBG
@>chr21:9882360-9882499-1
GCGGCGTACAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTNCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGAGGT
+
D@F@HI@CH@C??EE@GBDDF@AGFCDICCDD@B?FBG@A@FBDA?D?:CHI@I@CCED?H@C@BEEEHIEEB?HABADGABC?DBBEIA?BHCBCD@BE
@>chr21:9882360-9882499-2
GCGGCGTACAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCGAGGT
+
HGICEBE@ACAEB@?EIFBDDFA@AF@IDEFADBAA?CHF@?@IEIF?EDFFEAFCFFFGEADI@DGAIGD?GFFDFA??I?EIBC?HEBHGHBDH??C@
@>chr21:9882360-9882499-3
GCGGCGTACTGCGGTGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCNGGGTAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCC
+
GDBEDHH?HE?D?@DI?HBFGAE?AF?EEBC?BGAEBAFHIHHB@FC(BGG8CHFFDEG@EIBEBCHFH?FAGD@DI?IIGAFG@GGACCHIHG?FECEA
@>chr21:9882360-9882499-4
GCGGCGTACTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTCAGAGGGNCTTCTGGTTTCCCTTTTCC
+
HEIEFD@CIIBHFIAHHIDEACH?@BFFF?FHCHIE?DGAHEGF?AHIICHGDAGDG???EBIG@FDDGHH@@@CEIHGB9CF@2FGBG?@AGA@GDDDB
@>chr21:9882360-9882499-5
GCGGCGTACTGCGGAGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTTTTCC
+
@CAFCD@G@CGDE?BCFAHEDFC@@@@FAFFDCAGDIEEEG@BA@?DEHFHF?CCB@HFDEFA@IE@GAFFAIGEIAEAD??@EIHAACBCIC@GFFIF@
@>chr21:9882360-9882499-0
TCAGACGGTAATCAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAATGGAAACCAAACGCCCCTCTGAATCCTACCCACCG
+
BIIBEGCECFBAGCE@GC?G?AE??HEB?DIF@?C?BFHDB?BEBHI?HCDBIIGD?HE@CBCGI7AIFBGDIDGC(EHCBIH@@GBD?BBCCI@BCA?G
@>chr21:9882360-9882499-1
TCAGACGGTAATCAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAATCCTACCCACCG
+
GHAIE@BFCAFABEECHBFEF?FGBAHCF@CHIAA@AGDHCBDHHAE?@GHBAIFI@@BHEBE@D?HIFEIDBADFE?GA?HECHCFGEFADBF?I?IGF
@>chr21:9882360-9882499-2
TCAGACGGTAATCAGCCCTGAGTAATCAGGGTCAGCGACCAGTAAGAAGGGTTCAGTGTGGAAAAGGGAAACCAAAAGCCCCTCTGAGTCCTACCCACNG
+
FBDCIBHFGGGBD@GH@FHE??DGCF@@A?@DCBB@IBF@FIBCFFI?AF@CIBI@?FFHCA?GBAA?AIBE@BIA@DFGEACB?@C8?A?EBECDBG"C
@>chr21:9882360-9882499-3
TCAGACGGTAATCTGCGGTGTGGATCTCGCACTGCGGCGCCTCGCCTTGGCTGCGGAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCCCTT
+
?IIEEID?FFIAGDGBCF@CDEH@I@?CA@G?F@DHAGAGGB@ID?GEC@GAI%FFFGIGFEAA?AGC?FCHFCEHBBHEEDFHGCI??@BHIHGBCDCD
@>chr21:9882360-9882499-4
TCAGACGGTAATATGCGGTGTGCATCTCGCACTGCGGCGCCTCGCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTCACTT
+
BC@H@I@?HBA?8ED?IHDCDA$)DACCBDDCHB?BCF@EBFIEE0IBFDEEBIADEEGACHFFFFEI@@A?HFBEI@DFI@FC?EFDAI?AEB@C0FHE
@>chr21:9882360-9882499-5
TCAGACGGTAATCTGCGGTGTGGATCTCGCACTGCGGCGCCTTTCCTTGGCTGGGGAGAACCTCGGTGGGTAGGATTCAGAGGGGCTTTTGGTTTNCCCT
+
@BCGGDHDBCCACH@IACBIFF?BGG?CEBE?HFFDFBHICF72HAG@@EDHAACBDE?BEHGIDAFFFEGFBEADAA?DBGIA?BI@HA@EDBC3A?7B
@>chr21:9882515-9882643-0
ACCAATATGTCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAAT
+
BG@E,E?BCHDFAI@?@GEIDFF??AB??EGEEC@A@?CGFFA?IDDAHHBII?@A?D@@BFHCF@IBHCAAFB?FGBCFFE?H?G?CFEG@IABHAGGF
@>chr21:9882515-9882643-1
ACCACTATGTCAGCATTCCGAATGCGGACATGGCACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTANTGCTAATGCACTGCCTCAAT
+
C?FB@C@G@@?@CEDEIBB2CHAFI?FIDHAB"HEEG?FGD@HB?GFFBBIFF@D@BFA@EDI?AG?AAIHDAI@?DBE!GBABIAEHICF?C?CCA@IH
@>chr21:9882515-9882643-2
ACCACTATGTCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAAT
+
EDHG@HAH??HGIGGCIDFC@?H@IDACDEHEH?@?EHFDDAIAEFIHDBCBEDBECBEAIAGIID!F?CFGA@HE@?AG?FAIGEF@FF?IDAEEHECC
@>chr21:9882515-9882643-3
CCCACTATGTCAGCAAGGGGATTGCGGATCTTATATTAATATTNTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGCGT
+
<@AHGDBF?B@HCGG?F@CHHEHAGCDADFHHCE5H@EC2?AC8ICH?AIIIGFBCEBG?CI?HFFFFHIB?EFBCEHCGACDDEFBECACG?ACDEDBA
@>chr21:9882515-9882643-4
ACCACTATGTCAGCAAGGGGATTACGGATCTTATATTAATATTTTTGTATTGAGGCAGGGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGCGCGT
+
@@@CHDF@BF?FCDEHG?IBDD?,DGH@I@CHDAD?ABHIACEI@?FAH?F?IGDFGF&H@CB?GG@ECB@HHIBFACDD@DCIFFFGDDAC?HF!EDFI
@>chr21:9882515-9882643-5
ACCACTATGTCAGCAAGGTGATTGCGGATCTTATATTAATATTTTTGTATAGAGGCAGTGAATTAGCATTACAGGTGCTTGTTACANGAGCAATGGGCGT
+
GGEIBICHDC?H?ABH?D$DACC?GACFI@DHGD?5EADCB@CADGBIEF%?H?@EH?II1HBFECAG@AAA@HECFGBEB@IAGI'D@FABHGHCDEGF
@>chr21:9882515-9882643-0
CTCATACCACGCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCAACTGTAATGCTAATGCACTGCCTCAA
+
ED?FBCEGGDIB?IEF@B?HA@AHGEDACIBDGCH@?GHB?EB@CE@@CFBGF@CDFIHBIICGFEFACD?F@?#EEE@AHFHB@CAHGAD@HCGDB?@C
@>chr21:9882515-9882643-1
CTCATACCACGCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAA
+
B@CEH@HEBHF?G@HBIIF@D@D?@CGGD?HEGC@FBDDFDBH?H@EEBH?DIACHEH@BGAFHG?C@BDGEHCCGABDBFGIED@D@?E?HFBD?HICG
@>chr21:9882515-9882643-2
CTCATACCACGCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAA
+
GIG@BAFICECFICC?CGE@GDFGDBAB?BEEF@E@ADE??EDDICIHEFFHB?HDAF??AAC@DIEBFB?EGG@AHGCEII?H@ACHHHDEGCIIICCG
@>chr21:9882515-9882643-3
CTCATACCACGCAGCAAGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGCG
+
A?CDE?AHBI?@CCF@@EGFFCDCFBGIEFCGHBHAIIAD@@GIFA?I?BIDGEGBCDFCEBE@HF@FHD?ACBE@FIIGGEGHI@ICCECAEHHAEF@H
@>chr21:9882515-9882643-4
CTCATACCACGCAGCAAGGGGATTGCGGATCTTATATTAATATTTTTGCATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGCG
+
FCEBIF?EGB@AHFCGDECF@GFEB@?F@GBF@GAHHEAAAEAGIIHF+@GCCFDFHFHFG@BAEABCAFFEIC?@IIICBI@AFFEBBFDHHFBBCD@A
@>chr21:9882515-9882643-5
CTCATACCACGCAGCAAGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGCG
+
F?CAI?BGIE@BFEAIFGIHEEDAGEIFFCAFICCAGGBBD@@HHEAACHHEAD@F?HAIA@C@ECBCG@?GFH?HFGIHEBIHA?DAA@BHAA?IEDFG
@>chr21:9882515-9882643-0
GAAGGTCCTCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAATG
+
BACGEDCCBEF@DFBDFCHCIEGDCHCFHAA?CADGIHC@A@DDDACI?HHBD?H?I?EIA?AEBFAHBCGEBG?D@HEEB@?@EBHAED?BCAD@AEF+
@>chr21:9882515-9882643-1
GAAGGTCCTCAGCATTCCTAATGCGGACATGAAACCCAAAATGTGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAATA
+
CIFA?EE@EC?IAIADDCBFCGEIEF@@CAG?7DAHAA@@E?)BEDAI@C@IIIHBBHFHBBA?@A@DAEEEF@BFGIHIE?FFIFA?E?C@?CG??ICF
@>chr21:9882515-9882643-2
GAAGGTCCTCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTNAATA
+
C?H?F?BA?E?IEFCIG@G@HHI?IDC?HHFC?IGIH@HA@FA@HICFC@B?GBC@ECAE?ID?DEFHGHF@G@DD@IGIAHHF@AHHDIDIIIB)E?FA
@>chr21:9882515-9882643-3
GAAGGTCCTCAGCAAGGGGATTGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGCGTG
+
E?GDDE??BB@HIIHH?CDBDHHABDBIFAAD@BEFFAFIBDCDHEFGADC?DHIDHD?HI?A@BCHFIGHG@AI?BFHHHCC@ABFHG@DEFCC@B?IF
@>chr21:9882515-9882643-4
GAAGGTCCTCAGCAAGGCGATGGCGGATCTTATATTAATATTTTCGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGTGTG
+
GE@HBA?GIIDF@GIA?-H@@AEBFG?BFIFDFHAGBECABIAG6??HDIHG@HEED?DDIIBBCGAEFFCG@HII?H@DF?DCFIABAEGFGDAB9?@A
@>chr21:9882515-9882643-5
GAAGGTCCTCAGCAAGGGGATGGCGGATCTTATATTAATTTTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGCGTG
+
CGDBADE?G@@AEHIHGEIAFE?CGIFICBFEE?HCHF?7EEAIG??BFDI?@GFHAEGC?ABHBDFIHHGFDB@DEBGABDDBBE@AGGC@@GC@CDBC
@>chr21:9882515-9882643-0
GCGGCGTACAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCAATAC
+
FC@FBE?@?EGIEHCDDFHC@GCHEH@FHAAFHAF@?EA?BIH@@BFBDA@DGEAIAHBGBIE@FIIF?AFEGCBG?I@EA?BFIF@IICC?HH?ICHHC
@>chr21:9882515-9882643-1
GCGGCGTACAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATACACTGCCTCAATAC
+
F?BBACAGD?FDBFI@GDIIAAAEIGG?DH?@EDAGAFD@HDABHDACFEFEDAAAF?BCGEHBI?H?FAHIEEAEBEDDAG@GD9CGBEIEHHI@@@?I
@>chr21:9882515-9882643-2
GCGGCGTACAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCGTGTAACAAGCACCGGTAATGCTAATGCACTGCCTCAATAC
+
C@EIEH?DCHAIHDBG?@?@AEH@I?ECDGAE@@@BHG@HCB@ADGGA@?BCCC??A@D8AFFHB@EAGI?DG:IFFCIHIAGIIHAACBA@F@FD@?FB
@>chr21:9882515-9882643-3
GCGGCGTACAGCAAGGGGATTGCGGATCTTATATTAATATTTTTGTATGGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGACCAATGGGCGTGG
+
?F??CHHGHE?@ICHFHIIAIHECFDDGGC@DEHEAC?EAIIBIHG?G;A@@@FHHAIADACDBIEEEEGH@DGHCCADFAII@DHC=@FFGG?IDBFH.
@>chr21:9882515-9882643-4
GTGGCGTACAGCAAGGGGATGGCGGATCTTATATGAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTTTTACATGAGCAATGGGCGTGT
+
C*DIEBBADIHBIFBFBCADBB?@@DFFG@CE?D!AADGFCBII?ICGIICC@BHIDAEC?CIEA@IGFBCB?D@HI?%B?ABIACDDI@?AEDEF?A@C
@>chr21:9882515-9882643-5
GCGGCGTACAGCAAGGGGATGGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGCGTGT
+
HGB?EC?EAFF@IAD@HEI@@FAIBGEGIGGFAB@FA@FCHFD?@GF??2CA@AEACEIGC?HE@@A@ECHBC@GFBCBIG?EIHGF?DCC@@IA@C?C@
@>chr21:9882515-9882643-0
TCAGACGGTAATCAGCATTCCTAATGCGGACATGACACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCA
+
FACEGD??HA@G?G@I?HC@H@HCGDEAIAFEIEGGGCECFD@DB@DEIHIBAHEDICEHGB@D@H@IGFI?IFHFHB?BA??HE@BC@G?@EIGHG@E@
@>chr21:9882515-9882643-1
TCAGACGGTAATCAGCATTCCTAATGCGGACATGACACCTAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGTCTCA
+
IBB@CEAEHABEH@BEBFCA@AAIBCF??GI@ACIBBD?-I@DC@B@BEAGDDBAIGEI?IBEGAHCDHD?CGCF?CBG?DCBICIIGFDFECED.@HAC
@>chr21:9882515-9882643-2
TCAGACGGTAATCAGCATTCCTAATGCGGACATGATACCCAAAATATGACACGCCCATTGCTCATGTAACAAGCACCTGTAATGCTAATGCACTGCCTCA
+
CAF@AF@FGDCIDFHHHCDFABEF&FCGDGBBFHE%BIH@BDC??GIAIIFC?HG@BBFBGG@IAI@G?BEAGBFHBIDBHIDFDHBCH@CCFFAIHDH?
@>chr21:9882515-9882643-3
TCAGACGGTAATCAGCAAGGGGAAGGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGC
+
@?BFB@DB?FFHBIDIB@EEHDI+BHF?@BCBC(FB@GHF?BHGAAC?FCHCFC?HCBACBBCCDAHEHACF?DIF?FDGHE?IC@?@DB@BFHHHEH@A
@>chr21:9882515-9882643-4
TCAGACGGTAATCAGCAAGGGGATGGCGGATCTTATATTAATATTCTTGTATTGAGGCAGTGCATTAGCATTACAGGTGCTTGTTACATGAGCAATGGGC
+
GDHG??G?C?IIBHGFGE?FCA?ECCADAGGHAHGBEBHEF?CBE7EE?IAAE@DEFIHGCFI@DIBIBAHFHEHEGGA??CG?EIBIHHFACEEHABCE
@>chr21:9882515-9882643-5
TCAGACGGTAATCAGCAAGGGGATGGCGGATCTTATATTAATATTTTTGTATTGAGGCAGTGCNATAGCTTTACAGGTGCTTGTTACATGAGCAATGGGC
+
??BEGDII@BCBFFDGDG@AF?CFIGI?@AGEGGECCBDD?BD@CCAEBHCHCG@CH??D?EH0%CEIA'I@@GIA?EBI@CB@C?DHFEICHIDBA@@F
@>chr21:9885828-9885952-0
ACCACTATGTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTGACGCATTCCAGAGGCCACC
+
?@DIB?EADEA@GIIGGD@AAHFDD?CHI?BEH@AHAGEH@HGGFAGEI@ICCEA?I?@DDHBBBDFB@@AHDHHD@B?GFA@EF@CDCADG?A@@FCE@
@>chr21:9885828-9885952-1
ACCACTATGTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCNGGCGCTGACGCATTCCAGAGGCCACC
+
FHCIBBDAFC@CCIHEFIFCABDD?@HGBEHD?EBIB?CAEI?IAAFCFDCABBEBABDFFCGFABIFG@EGI;C?FC@@CDCFACBF@EB?BBFDFDG?
@>chr21:9885828-9885952-2
ACCACTATGTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGACTCCACCAGGGTGATCCTCAGGTCTGGCGCTGACGCATTCCAGAGGCCACC
+
EDIBBGGHDGCGEE?GGA'HEFA?GADB@IDFCGECCEEDCEEF@@IF)AIFI@GABBHHEHE@EIHCBHFH@EFIBBFE?I@FBBIDIAEIEGDI?BAI
@>chr21:9885828-9885952-3
ACCACTATGTCAGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCACNAGAATGCGTCAGCGCCAGACCTGAGGATCACCCTGGTGGAGCCACC
+
HB@GG@FIIG?DIAAC@@CCEGB?GECHEDEEBGID@@HFEFHHFAGCBHH!F/"A?HH?IAHF?E?@A?GBFCBE@FC?DDCGE?D?IDGDIBFB?GAG
@>chr21:9885828-9885952-4
ACCACTATGTCAGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTNGAATGCGTCAGCGCCAGACCTGAGGATCACCCTGGTGGAGACACC
+
G@D@H?A?AFIAFCGDEBAHBB?BHID@B@I@ADECHF??BAC@B@G@G?EC?A)CD@GA?:EGHGIFI@H?FGAFIEIDADD?D@?BIHBF@F?(IIBI
@>chr21:9885828-9885952-5
ACCACTATGTCAGCTTGGGCGCCCAGGCGGCGGAGCATGGTNTGGGTGGCCTCTGGAATGCGTCAGCGCCAGACCTGAGGATCACCCTAGTGGAGCCACC
+
GG?CG?CCIGHII?CD?HGFCCEDGC?HFIABGF?A@FGC?8?A?FD??EC????DEBAF?B?IHG@CICGICECBI@FEGDAI@@HG.HHHDIAAEIHA
@>chr21:9885828-9885952-0
CTCATACCACGCTGCTCCAGNCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTGACGCATTCCAGAGGCCAC
+
DHCI@CCEG@H@CGDHBGCE>FE@?B?ADBGD@IDD?@ACFADFEGB?D?I?@GC?IECIGHAIGIED@DAIECBGHHAIHBIIB@GGBAHB?BDEGDFI
@>chr21:9885828-9885952-1
CTCATACCACGCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTCACGCATTCCAGAGGCCAC
+
GI@BCEBFAGDGCIGEBHIH@ADAIH?AIEDIGGHCFCAEFCIEAHAB?G@FIBD?GDE@I?AFBCIC@?EGF?AHGIG@CHI?I?D?I??AEHICCEAA
@>chr21:9885828-9885952-2
CTCATACCACGCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTCACGCATTCCANAGGCCAC
+
AGA?H@BBI?IH@EBFCGCD?@?I?FHIAC??GHFHAHDBHHEEAF@AA??CFCEGADBEC?G@A@IGFCAEAADIAFCCHAHGHFE??GHB.BEA??F@
@>chr21:9885828-9885952-3
CTCATACCACGCAGGTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTGAGCGCCAGGCCTGAGGATCANCCTGGTGGAGCCAC
+
?GIADFI@EIGIGD,CDCAIIADCIBBGEHHAFC?C?DDGAIAA?FAEG?IC?CG??@ECGBGH@IBB?C?GH.??BFGI?HAHF)AF@BHCCBB?BAFH
@>chr21:9885828-9885952-4
CTCATACCACGCCGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTCAGCGCCAGACCTGAGGATCACCCTGGTGGAGCCAC
+
EFE?IEAFBDC?.CHEDA?FA?A@BA@G?EF@@BGADDCBHEHG@GCIH?GIECCGCFHAFGF@GHHFDBHA@HGADIEHIEDDFBBCI?DBHG@?EA@F
@>chr21:9885828-9885952-5
CTCATACCACGCAGATTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGACTGCGTCAGCGCCAGACCTGAGGATCACCCTGGNGGAGCCAC
+
GDFGIADGGEHIGF-GECGHCAF?ACGDFC@F7BIA?CHECHFIDCFDHBCEDICCEH6DHDI@B@DH?EEIG?IE?AGDHAHIBF@GC4A<GD@IHD@G
@>chr21:9885828-9885952-0
GAAGGTCNTCTTCTCCAGGCTCCAGCAGAGGAAGATCGGGGTAGGTGGCTCCACCAGGGTAATCCTCAGGTCTGGCGCTGACGCATTCCAGAGGCCACCC
+
H@E@DGA+IA?>GBDCD@?BGBI?GI?GAE?FDGA!F@FFCBD?DEDAFEIEGC??H@@G7EBEA@CAHG?ECBHH?GF?GHAEFBBFI?@HCICIHIH@
@>chr21:9885828-9885952-1
GAAGGTCCTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTCACGCATTCCAGAAGCCACCC
+
A@?FHGEIE@EADDH@GFHACDGD@EF?HCHHGDGE?II?@IFIHEDCIDEFCEGCF?EA?FE@FGG@IDEADBB?EEHAICHFBGCCHBAC.AB?FCEB
@>chr21:9885828-9885952-2
GAAGGTCCTCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTCACGCATTCCAGAGGCCACCC
+
HAHHGA@AIABAI@HDDEG?@?FIHGCCFD@IHH@?BBEGACEHIBA?DICBA@CD@@CG@GEIIEDGA@CBDB?DBBBHFIA??@EAFEGF?DHABHIE
@>chr21:9885828-9885952-3
GAAGGTCCTCAGCTTGGGCCCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTGAGCGCCAGACCTGAGGATCACCCTGGTGGAGCCACCT
+
@GIAHCE@EHDHDDGHE?G6BGGHHCAFEAC?C@CHEAA?@GEF?CAEDAGFH@EHDE?IF@ABH@D@@CBB?BCEDAHABHGI?A@AH?DEHHDEICHE
@>chr21:9885828-9885952-4
GAAGGTCCTCAGCTTGGGCGCCCANGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTCAGCGCCAGACCTGAGGATCACCCTGGTGGAGCCACCG
+
?EI@GDHIAAHIE?HE@@?C@IH?<?@GFIEHBBFCEHFDHDGDIDEB?DDGDH?FB@EIGHCDGCA@I?@I@DG?DE?EGHBFHBGHCEIBBBE@?AC$
@>chr21:9885828-9885952-5
GAAGGTCCTCAGCTTGGGCGCCCAGNCGGCGGAGCAGGGTCTGGGTGGCCTCTGGAATGCGTCAGCGCCAGACCTGAGGATCACCCTGGTGGAGCCACCT
+
BDIACIGFB@HD?GCG?@GCGGDGC$HIEAB@?#?F!@GIBIC@FADCFADIGCC?HEGCI?FBGIIEFABC@GGHDI?BCGEBICAFCBGBCBHDDCD@
@>chr21:9885828-9885952-0
GCGGCGTACTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTGACGCATTCCAGAGGCCACCNA
+
B?FBEFIIFCDBBB?AAGAC@EAE@ECIAFBBC?DAAEEDEDAGHF?H?@HBGEFB?EGIHAIAGAIBGDCC,ACHFDCAHECC?FIHAGA@FGHAEC)@
@>chr21:9885828-9885952-1
GCGGCGTACTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTGACGCATTCCAGNGGCNACCCA
+
ADGHHIAIEA@?DHAE?D@BCDDBE?CDIC?C?EDEHDCEH@ECEAI??H?EFII@DB?HCGH@AEHAA??E@@FAB@@@HDGGCI@HHI.FFI7BBFCB
@>chr21:9885828-9885952-2
GCGGCGTACTGCTGCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCCCCACCAGGGTNATCCTCAGGTCTGGCGCTGACGCATTCCAGAGGCCACCCA
+
HCCI@EHFFHEA?91DHI@DAIA?GGHHEFC@?@AC?@?IAA?IBFAF2G@EIE@BCH@"CIGEI?GF@FHG@ED?@HDHEAD?F'EB?F@EDAGH@ACD
@>chr21:9885828-9885952-3
GCGGGGTACAGCTTGGGCGCCCAGGCGGCCGAGCATGGTCTGGGTGGCCTCTGGAATGCGTCGGCGCCAGACCTGAGGATCACCCTGGTGGAGCCACCTA
+
GFFF8FFEFH?BE?G@FGHHD?GG@I?@H'CEADF?DHEGEG??HFBCCHAHDGA@@IGAED"EA@IE@FCCIFCBAECICH@EEG@?DCFCCED@I@GB
@>chr21:9885828-9885952-4
GCGGCGTACAGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTCAGCGCCAGAGCTGAGGATCACCCTGGTGGAGCCACCTA
+
HAAHE?@DHGA??ACFEEBHIGGCC@I@CDG@FI@@A?BABGEAA-I?I?CBFEAHBDBG@D?I@?FAEFB:DG@HIICEFBAGCA?IA@GDI?@IIA?C
@>chr21:9885828-9885952-5
GCAGCGTACAGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTCAGCGCCAGACCTNAGGATCACCCTGGCGGAGCCACCTA
+
HC-GFEEGEIAEDFC?FC?EAB?ID#FCA???DI@BE?CH@@BEHG?II?AFE??HDFBIGEC?AAIDAHHCIE!@CHG@D??CD?@D%A?CA?D?IBG?
@>chr21:9885828-9885952-0
TCAGACGGTAATCTGCTCCAGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTCACGCATTCCAGAGGCCA
+
AHCDHBFEFFHD?@GBG@?@IGIEHHIBHGHI?G?I?CHEHE?I@@CHFIFEDAB@HEI?IIEI@?AIFIGEGGEEA@BB@IF?HG7AFHI?DD@ICCBH
@>chr21:9885828-9885952-1
TCAGACGGTAATCTGCTCCAGGCTCCAGCAGAGAAAGACCGGGGTAGTTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTCACGCATTCCAGAGGCCA
+
?DAB@HIB?HBGCHDBIE?B@IGDHCGH??GBH'?@D?AIIH?EACH,@BH???EDCDEI@@IGC??HIHEB?B?B@@AFADAEDHHAI?EE?GEF?IB?
@>chr21:9885828-9885952-2
TCAGACGGTAATCTGCTCCCGGCTCCAGCAGAGGAAGACCGGGGTAGGTGGCTCCACCAGGGTGATCCTCAGGTCTGGCGCTCACGCATTCCAGAGGCCA
+
G?BDEEFBEHHHIGF@F@F1FEGGEDDD@GDEDBHEIAH@BC@H?@G@G?A?@GB@GB@EFCIIIG?IE??CEACBIIFAF@EA@GECCADBCHDACGBA
@>chr21:9885828-9885952-3
TCAGACGGTAATCAGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTGAGCGCCANACCTGACGATCACCCTGGTGGAGCCA
+
IIGFEBCIGHDFCEDB???CCCIGA?BHAG@BI@BFGCCCFHHHED?@ICGHHH?FBAFIABBDDGBBBDCIF1@HIAE@2HAB?C@D?F?@CEF?CFIB
@>chr21:9885828-9885952-4
TCAGACGGTAATCAGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGNCCTCTGGAATGCGTGAGTGCCAGANCTAAGGATCACCCTGGTGGAGCCA
+
BEGIC?HCFCD?GFDGFD??FEDABGFCGGG@ICFED?FCFIIFIIACD@6CBEAEA@FFAHGFGH@?9ECB?DH0BB.FABBFBI@B?HACI@AHBAH?
@>chr21:9885828-9885952-5
TCAGACGGTAATCAGCTTGGGCGCCCAGGCGGCGGAGCATGGTCTGGGTGGCCTCTGGAATGCGTGAGCGCCAGACCTGAGGATCACCCTGGTGGGGCCA
+
AFI@DGGEDIDI@DGFIA@?DFDFFF?E?@CBA@@GGD?HIFFACHDDFFFA@AE@@HHDHHFCCDDFADAGDADGD?ECBDAI@A@D@EGEG?H3DIII
@>chr21:9890867-9890951-0
ACCACTATGTCTGCAATTTTAAGTTTTTTAGAAAACACCAAATATTTCTCAAGTTAGAGATGTTTTAATAAAAACCGTCATATTGTACTGGCAGAGATCG
+
BBCEAD@FD@GBEAD?E@A%8BFH?F?DECIHCEGACD??GD@@DAE@@E?@IBCDA@BA@HBIDIFCCBGH???8AGAEDGAFBAHFIGIHBC@G@G@I
@>chr21:9890867-9890951-1
ACCACTATGTCTGCAATTCGCAGTTTTTTAGAAAACACCAAATATTTCTCAAGTTAGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGATCG
+
B@B@@GDCIBFIGGGI@C;IBIFIH?ICHGDCEICDEBCF?DGFABDIFAFDBIBHGD@@DHF??C@IH@EH?I@DAFEDEFGCED@ECE@EBEC@BAHF
@>chr21:9890867-9890951-2
ACCACTATGTCTGCAATTTGCAGTTTTTTAGAAAACACCAAATATTTCTTAAGTTAGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGATCG
+
IH?AGI?EAGI?DI@HCAIDICE?@FHDCDFE@GIGCHABD?IBDGA@C<F?GH@@DDHCFB?B?EB?DDEEBIIGBIBGGDFFF@ECADIIHDIDHACE
@>chr21:9890867-9890951-3
ACCACTATCTCTGCCAGTACAATTTGACTGTTTTTATTAAAACATCTCTAACTTGNGAAATATTTGGTGTTTTCTAAAAAACTGTAAATTGCAGAGATCG
+
GAGFFBBH&B@A?F??GGBDFIF;GECIDA@DFD?CGCF@ABBE@CH@HIDI@HD<FEBA@G@D?H@H?DAF?FBIEFGCFCIE;A@C@GFIG@C@BIFF
@>chr21:9890867-9890951-4
ACCACTATGTCTGCCAGTACAATATGACTGGTTTTATTAAAACATCTCTAACTTGAGNAGTGTTTGGNGTTTTCTAAAAAACTGCAAATTGCAGAGATCG
+
BHGEEAGHEEICBIDFIFH@?HDHH@GAB?.DD?EEAIIBFGE?CIIHEBIF@ACDD+F%D'HBAGB-A?@GGEIEDBIAF@@GCE@D@IB@AHE@GD?E
@>chr21:9890867-9890951-5
ACCACTATGTCTGCCAGTGCANTATGACTGTTTTTATTAAAACATCTCTAACTTGAGAACTCTTTGGTGTTTTCTAAAAAACTGCAAGTTGCAGANATCG
+
I?EIICA?FIHB@FBI?H8HC<@EG@ED@EFIHFDFFCDD?F??C@D?CCECBA@G?@H'C&IHICBAIACGEBHI?BHB??B@@G@8FBCFC??>C@I?
@>chr21:9890867-9890951-0
CTCATACCACGCTGCAATTTGCAGTTTTTTAGAAAACACCAAATATATCTCAAGTTAGAGATGTTTTAATGAAAACAGTCATATTGTACTGGCAGAGATC
+
ED?ECHG??@G@G@@B@BHG?I@EI@B?A?G?IHCF?HBF?BABI@GC@HD@@CE@IEDFB@@@@IEF@D#DFC@F??CCAGFDEGHCDBBA?DFBF@DD
@>chr21:9890867-9890951-1
CTCATACCACGCTGCAATTTGCAGTTTTTTAGAAAACACCAAATATATCTCAAGTTNGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGATC
+
CCBCAFBGEGG?@BDDHBFCBGICEHI?IGGDFCIIHBFEEECBE@EGIHI@E@DG$?BB??GIIEADIC/BIGEFEDI@HIB?DDEDBEHBF@D@FAII
@>chr21:9890867-9890951-2
CTCATACCACGCTGCAATTTGCACTTTTTTAGAAAACACCAANTATATCTCAAGTTAGAGANGTTTTAATAAAAACAGTCATATTGTATTGGCAGAGATC
+
@CCEGH?HGFIBGBHC@B@I?I@1EBCDBF@FAAEBDAGDFI'?HA@C?I@IGAECBEBAI.FIFHBFFC?DHGBAGFCGHHHDCCFC=C@DEICCGIFG
@>chr21:9890867-9890951-3
CTCATACCACGCTGCCAGTACAATATGACTGTTTTNATTAAAACATCTCTAACTTGAGATATATTTGGTGTTTTCTAAAAAACTGCAAATTGCAGAGATC
+
G?@AF?BBGBCAHDEDH@IHBGF?DGBGDCCECH?<GIFAFIIHDDHCI@@ICHA@DIGFCCCHEH@BEDG@AB@CFI@GBH@@?H@@DADHFHHDAACG
@>chr21:9890867-9890951-4
CTCATACCACGCTGCCAGTANAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGATATATTTGGTGTTTTCTAAAANACTGCAAATTGTAGAAATC
+
EDDIBEE?FBD@FFFIIBCG:AC??G?BECBICCI@B,GGAG@?EH@ED?A?G@GGB?GE?BH?IGDEEHCIBBEDCF@A3A@??DE@F@DC9EGE)GCI
@>chr21:9890867-9890951-5
CTCATACCACGCTGCCAGTACAATATGACTGTTTTTATTAAAACATCACTAACTTGAGATATATTTGGTGTTTTCTAAAAAACTGCAAATTGCAGAGATC
+
A?FAAIB?AFHDC@AECDBIBBG?D@GEGDIAB@CCFCCADCDACBI+EBAGEAEI*GDBDEDCFHBHDAFFDI@IDDEID?BEAGI@HI@I@FHAFHAA
@>chr21:9890867-9890951-0
AAAGGTNCTCTGCAATTTGCAGTTTTTTAGAAAACACCAAATATATCTCNAGTTAGAGATGTTTTAATAACAACAGTCATATTGTACTGGCAGAGATCGG
+
9EA)HF+FD?F@?HGCFDCCDDG@AAH@CDB?GBEBGCGCC??@HE@HF4CHD@GGHBFIGE?FEE?GHG4FDIHD@BBIEE@??BE?BFCGHCACIFGG
@>chr21:9890867-9890951-1
GAAGGTCCTCTGCAATATGCAGTTTTTTAGAAAACACCAAATATATCTCAAGTTAGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGATCGG
+
?IFBCCEDCDHCF@ED&B?HFGDGBFABGFIBFDH?IIEEGIEAH?AHAFAGDFFAD?BCBEBB?GIHAFIHDDI?EGI@?IECD@@CBE@AE@CFIFB?
@>chr21:9890867-9890951-2
GAAGGTCCTCTGCAATTTGCAGTTATTTAGAAAACACCAAATATATCTCAAGTTAGAGATGTTTTAATAAAAATAGTCANATTGTACTGGCAGAGATCGG
+
@F@?IEG?ABGFDD@?DFFBDHAH)BIIHBF?HC?@IFBH@E@BD?CHCDF@AG?HGHIA@G?EGIHDI?EFE.?HBHG4H?CIGIEAAEAF@A@DDBFG
@>chr21:9890867-9890951-3
GAAGGTCCTCTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGATATATTCGGTGTTTTCTAAAAAACTGCAAATTGCAGAGATCGG
+
HB?BB?F@GEIC?FB?H@?FFHFCGDH@CF@C@?DEIBIEIBAGB@EHGHIHIIA@?FBBBBG,@C@BIHABFAEDEFEHAAHB@DGIFI@FACBC@IFC
@>chr21:9890867-9890951-4
GAAGGTCCTCTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGATATATTTGGTGTTATCCAAAAAACTGCAAATTGCAGAGATCGG
+
?CIB?I@?GDCHA??@GAFBGGICHHBC@?H@ABGBGF?DE@FIHCEC?GBDIFIHG?F@DEEDIBD@?G9B@(GBCAHGFEIGEBAB?CC??F@ADCA@
@>chr21:9890867-9890951-5
GAAGGTCCCCTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCNAACTTGAGATATATTTGGTGTTTTCTAAAAAACTGCAAATTGCAGAGATCGG
+
FFGAHGDE4FEICA@CDIC?CGFDEDBBE?IEIICFG@FFBHDH?DA&B?A?CHB?E?GC@I@DEGHG??CF?D?EAABDG?IHE@@@FB?B??HHAB?A
@>chr21:9890867-9890951-0
GCGGCGTACTGCAATTAGCAGTTTTTTAGAAAACACCAAATATTTCTCAAGTTANAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGATCGGA
+
@E??HCCDEHBAGHFH9@DI?CFD?EBCEA@BDEA@?CADFCFDF@G@@F@DHC7G@D@AAG@BHAIDAB@ID@C@AFD?G@DIBADIFCCIDAIIF@@E
@>chr21:9890867-9890951-1
GCGTCGTACTGCAATTTGCAGTTTTTTAGAAAACACCAAATATTTCTCAAGTTAGAGATGTTTTAATAAATACAGTCATATTGTACTGGCAGAGATCGGA
+
FDA1IB@@@??EEFAFFAFEBCHDHEGFBBE?FADBC?AGDECIIGECA?I@GECD?@GFAFC@EBFCHA/A?DDHFEH?EBAHCC+AHFD@?AADDHIH
@>chr21:9890867-9890951-2
GCGGCGTACTGCAATTTGCAGTTTTTTAGAAAACACCAAATATTTCTCAAGTTAGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGATNGGA
+
A@AH@BGC@BG?CABCHIIGF@CAH?D@GFE@GBCCFGF?CBCACDA??BA?F@BEIEEHHCHGHB?D?DBDF@@EGE@BIGEFGGDCCH?@EEIG;AAD
@>chr21:9890867-9890951-3
GCGGCGTACTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGAAATATTTGGTGTTTTCTAAAAAACTGCAAATTGCAGAGATCGGA
+
CEFGICIBG@HA?CDG?EICIHC@EDHCG?B??IAGHFC?@F?GBI?DDGFIBAFH@BDCFBBIE?DAIHAAEG?FDGE?CGGHBBIDFAFEE?AAFDGB
@>chr21:9890867-9890951-4
GCGGCGTACTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGAAATATTTGGTGTCTTCTAAAAAACTGCAAACTGCAGAGATCGGA
+
DFC@HADCEEH?A?DHEIICAH@E@H?CCDGIEDHABBB?AIHBGFGHBCGA@?C@IED?IAGEECBI&AGCG@CDBFBH?EIDD?:HDFFFDIDEGDFC
@>chr21:9890867-9890951-5
GCGGCGTACTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGAAATATTTGATGTTTTATAAAAAACTGCAAATTGCAGAGATCGGA
+
EIAABACHHFAACACGC?II@E?IFGE@A?GIH@BGCICG@DIG?FB?B?BH?BHGAABBI@AG-?G?HAB'IHHD@AGFD@EF?I@?BIFFA@@AID?H
@>chr21:9890867-9890951-0
TCAGACGGTAATCTGCAATTTGCAGTTTTTTAGAAAACACCAAATATATCTCAAGTTAGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGAT
+
C@I@AIBB@CHCF?B?FGG?EGAC?BFGE?IBDDGE?IFAGDDABHFEFAIABGI?ECFFHIBDEBIA@FABIEEEBE?E@FDHGI@?HG?HBAHAFDDF
@>chr21:9890867-9890951-1
TCAGACGGTAATCTGCAATTTGCAGTTTTTTAGAAAACACCAAATATTTCTCAAGTTAGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGAT
+
?IGFDFECAFFCHFAIFGHGBAI?AHAGHIHBEAGGIA?FE?EG@H?E?GGH?FEGEDABDAEAIF?ICIBBHHIFCECDEDHI?E?HCGHGCC?AHBAE
@>chr21:9890867-9890951-2
TCAGACGGTAATCTGCAATTTGCAGTTTTTTAGAAAACACCAAATATTTCTCAAGTTAGAGATGTTTTAATAAAAACAGTCATATTGTACTGGCAGAGAT
+
DI??E?CE@IFGBGCD?EGGFBHAGFDC?C@E?HGEFCAB?ID?IDBGFB?@BIGIIGGI?BGECC?E??A?EAG?D@@@GHIC?H@B@@D@EAD@@CFG
@>chr21:9890867-9890951-3
TCAGACGGTAATATGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGAAATATTTGGTGTTTTCTAAAAAACTCCAAATTGCAGAGAT
+
FDCC?BEIHFDA:HBGBCD@GDAAHG?EIFGBEGHFHCGGADHDHECEB@G?ABBAI?FFEF@EF@CECHFG@DDAGHC?EDFIB4BBEA?ABFA@FBE?
@>chr21:9890867-9890951-4
TCAGACGGTAATCTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGATATATTTGGTGTTTTCTAAAAAACTGCAAATTGCAGAGAT
+
EFBCHFFGD?F?GCECEDIGGDDFDHCEG@HGDEIBEAFHAA@HBFA?BCCEGCA?BHA@IAIEBDFIAD@?DEHI@IHHA@FICCADCFDG@BI@D?GH
@>chr21:9890867-9890951-5
TCAGACGNTAATCTGCCAGTACAATATGACTGTTTTTATTAAAACATCTCTAACTTGAGATATATTTGGTGTTTTCTAAAAAACTGCAAAGTGCAGAGAT
+
GBF@DIG=GB?AAFHIB@CD?BEHFID?GIED?FFFAEHB@DH?IFCDIFFIDDFIHBBIABHGECHCFF@BEEGFCIDADIDE@E?FGF4B@ADFBHI@
@>chr21:9890948-9891037-0
ACCACTATGTCAGCAGACAAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGAAATTAACATATGTAAGGATGATCTATTTGCTGA
+
FEF@A?CCGAGF@DIAFAIB?@@CBAHBBAG?AG@A@9BGIHB@EFGACF@E=CDBFCAI@GFCAG,CA?HAFDACBI@EDDFHFGHGA&FFIBCG?FFF
@>chr21:9890948-9891037-1
ACGACTATGTCAGCAGNCAAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCGGA
+
HD=BDBAFAGEI?IAF<A@@?EGIFIDI?FDDFC%CAHCCGIEHADD?BBD?G@@HHAEEAHB@GB?EEDGGID?AHAADABFIDFIDD@FAD@FGD8EC
@>chr21:9890948-9891037-2
ACCACTAGGTCAGCAGACAAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGA
+
ADGAB?G0ACAACBHD@FCCADGEG?IEC@FDE@IBGAD@I?@GC?G@GGAGAC@HF@BHAAIDA?BHID?DH?AB?@GBI?FC@BDEEAFFC@@CFE@D
@>chr21:9890948-9891037-3
ACCACTATGTCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTACGCTGA
+
HDHEFF?DFDGH?IFI@GHCAF?AEBD@@?BDEF@@GBF@HC@CBFAF?HB??D?AH??DFI?H?CHCDHEGACGBBG@GAAEI@CDACIIFB.2DI@FD
@>chr21:9890948-9891037-4
ACCACTATGTCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGCGAAATAAAGGGCCATTTTATTTGTCTGCTGA
+
AH?IHF@!FH@?ECHAAD?H@?IDCECB?GGAGIEBFFACDCDCBID@E?B@?AA?EI@?EFHACE?F!CIAIFCACFH?@BFIDIGDD@I?IBFICI?B
@>chr21:9890948-9891037-5
ACCACTATGTCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCTGA
+
@EEHDACBAC@IFDDFDHAICF@CF-?G@HD@@CDIGA@G@BEHED@?IFGBAHH?GDABGEAFHA?FICIBC@CHA?AH&HFEBAGG?IGGGDIC?IDD
@>chr21:9890948-9891037-0
CTCATACCACGCAGCAGACAAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTG
+
ACEE@?GGIHEDDBIFCCGHI?@GE??ACHHIAHEDEIAEFFFABI??I!?I?@EDHABGIAC@DE@?GDGBDII@E@DBCGFCAE@DE?I@ACH?AE@@
@>chr21:9890948-9891037-1
CTCATACCACGCAGCAGACAAATATAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAGCATATGTAAGGATGATGTATTTGCTG
+
GDEB???BDHFDFHGIIA?HCAB@,G@EBBGFHB@CECHC?DIIEDFEHGHF?IBIE??EIDH??EE@EI@GF'@DCEH@CEHIG?G$B@DCE@GGBGB?
@>chr21:9890948-9891037-2
CTCATACCACGCAGCAGACAAATAAAATGGCCCTTTATTTNACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTG
+
IBBFAH@EBBC?C@ACD@EGGFBFA@FAA?@EBDDABAED7AIAAGDEAADEIGH??GGHIEDHFEHHEBIBBB@E?GIGGIDD@B???HE@BEDIGD?F
@>chr21:9890948-9891037-3
CTCATACCACGCAGCAAANACATCATCCTTACATATGTTAATTCCCTTCCAATTTCTAATTCTCAACTGTGAGATAAAGGGCCATTTTATTTGTCTGCTG
+
AGAFFGC@FF@EA@GGII.AADAFCC@GHF?AAEG@G@AGDA?=CCHA?HCDHGGG>FBEGBGDEEFHCHCC:?@HDH@A@GA@DCDHC@AECBCIHDEA
@>chr21:9890948-9891037-4
CTCATACCACGCAGCAAATACATCATCCTTACATATTTTAATTACCTTCCAATTTCAAATTCTCACCTGTGAAATAAAGGGCCATTTTATTTGTCTGCTG
+
@C@@DIIC@HB@E@@@HGB@EAHEBI?FIBIAC@CI%IEAIAB?@GHI@CG@ID@A?AB?HDG?G>CFIFEADDGHEI??BIHABGEIG@A@CFBH%DH?
@>chr21:9890948-9891037-5
CTCATACCACGCAGCAAATACATCATCCTTACNTATGTTAATTACCTTCCAAATTCAAATACTCAACTGTGAAATAAAGGGCCATTNTATTTGTCTGCTG
+
HCHBHGEC@HEBA@BG@?BAEC@F@FDA@FHA:BA?AFI@AA@BAAG?C@G@6IDGBIII7D@DEFD?@ICDICA@C?EIDHADDC2FCBGAG@HECCFG
@>chr21:9890948-9891037-0
GAAGGTCNTCAGCAGACACATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTCAGGATGATGTATTTGCTGAG
+
DH?F?HA-HCEBECIBEI9ABEI?ECGCIHEDHG@?G?DEEHGIBA@@CFBEEC@DAAH@C@A?ADFBGCCEFIG@HBA<BIBHD?@?BGG@FDA@CCGI
@>chr21:9890948-9891037-1
GAAGGTCCTCAGCAGACAAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAG
+
EBB@DCHHDFDHB@ACHIDCGHHG@@GAEEBGDCBGIBBCFIE?HGGIGGDG?HDFEA?@EC@HCDDBCCFEBHDCBFEEGB?CCGEBD?CCCAIHDE@C
@>chr21:9890948-9891037-2
GAAGGTCCTCAGCAGACAAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAG
+
C?D?GFGHC?GFADGDF@?DFGD?HII@CGC?@GGCHFFC?GHFCF@BGAA?EAHIHC@BEF?HDFDDAD@?CEEDACCDAI?@FBCEAGFGC@@GEFG@
@>chr21:9890948-9891037-3
GAGGGTCCTCAGCAAATACATCACCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCTGAG
+
H?>F?@E@EEH@?ICGFFAFA?@;HH?@E@IB?ICC?BCAADAG?EBIEB@CAAIEFAEADCDGCFCB@BAFAC?GHDDBIH@EG@AGBABFI@ICDBBA
@>chr21:9890948-9891037-4
GAAGGTCCTCAGCAAATACATCATCCTTTCATATGTTAATTACCTTCCACTTTCAAATTCTCAACTGTGAAATAANGGGCCATTTTATTTGTCTGCTGAG
+
CHBFHGEFACCFHHG@AHGHFBAAGFAA$HBCAH@?CC?H??IG@GGAF$?ICHADHA?EAFB??DGFI@?HIGE-H@?EB@EAHB?FBHICDFGFCFGD
@>chr21:9890948-9891037-5
GAAGGTCCTCAGCAAATACATCATCCTTACCTATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCNGAG
+
FGDHFDDAGGGBE?FDII@B@BC?H@HABI<BAHIEGA?IG@BCCICIAHFEIIIBEIFDD@B@FGFFFDDB?HB@GGBIAD@A@HECAGAGBCBF4GBD
@>chr21:9890948-9891037-0
GCGGCGTACAGCAGACAAATAAAATGGCCCTTTAATTCACAGTTGAGAATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAGA
+
BGCCBDC?D@HGGAH@FF@AH@DG?HGHBG@C?I2DDFIDHH?H@EEHEF@??CHDG?BBE@GB@BI@@IHHDI?GCFDBFBI?AFBDAE?@B?GDFD@@
@>chr21:9890948-9891037-1
GCGGCGTACAGCAGACAAATAAAATGNCCCTTTATTTCACAGTTGAGAATTTGAAATTGGAAGGTGATTAACATATGTAAGGATGATGTATTTGCTGAGA
+
C@GGEBCBABBCBEGEGIIDAEHAID%@?BEAF@HC@H@GIFAB@FDI@F?AI?@?FGBFACBGE-DCEGH@IE?DBH@@?D@GDHBDCG@?II@FEGF@
@>chr21:9890948-9891037-2
GNGGCGTACAGCAGACAAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGGAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCTGAGA
+
G)ICH@CIA?BBIEE@ICDDAGAADAG?GFAFEF@?AD?HFHAID@ACD$ABA2BI?@BGFGEA@??GEDCBH@DHCB@BDEECFEBFBF??@IEI@CE?
@>chr21:9890948-9891037-3
GCGGCGTACAGCAAATACATCATCCTTACATATGTTAANTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCTGAGA
+
II?AIEGDDCC??@@BG@@E@I@?B?CGAGA@ADDI@C7HFHFIIHB@?DG@HEEGFCEHDGDD?@ABEHCIF@HA?C?DHDG@?EEDDEBACEFACCDI
@>chr21:9890948-9891037-4
GCGGCGTNCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCTGAGA
+
FD?@BG?;B@G?BDGDG@CDAECFIFDEG?IIDGCIDDDAB@IIBIDHFFFIACBIDCHACD@?EBDBCFBADEF?@?H@CBB?IIHIFHBAHIE@FEHI
@>chr21:9890948-9891037-5
GCGGCGTACAGCNAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCTGAGA
+
CIDAI?FDIDAC;?H?CG@HG??@AICAGDBIB@HGFFI@D@ICI@HBADAGEAD@CC@B?BDE@HEAE?GEGGCCCGEE@A?FD@FFFDIE?D?BHG@D
@>chr21:9890948-9891037-0
TCAGACGGTAATCAACAGACAAATAAAATGGCCCTTTATTTCACAGTGGAGAATTTGNAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCT
+
G@E@BH;?DEEFCB/FGECHF?CGIGIEIA?DG?IA@F@GFCH@EI?4HDEFFFCIG7AAA@GC??@FFFI@HF?CBCFBBBE@CEE?EGBGC@GCG?IE
@>chr21:9890948-9891037-1
TCAGACGGTAATCAGCAGACAAATAAAATGGCCCTTTATTTCACAGTTGAGTATTTGAAATTGGAAGGTAATTAACATATGTAAGGATGATGTATTTGCT
+
AAID?GCDB@@CIF?G?HCCGF@IEBA?B@ECFGBDHH?DDFBAFHDBFIH;EHHHAFBH@GDCHGH@CHB?AC?G?BDCFFD?F?G@HHBFG?H?HFGI
@>chr21:9890948-9891037-2
TCAGACGGTAATCAGCAGACGAATAAAATGGCCCTTTATTTCACAGTTGAGAATTTGAAATTGGATGGTAATTACCATATGTAAGGATGATGTATTTGCT
+
@HDECIGGGDDHAEB?HEHB"?HICBFHIGBHG??FF?BGH@?IGIBIACACCBGE?GGC?G@EG+DEHH@DIF/IBBG@H@@@ECECHECGG?IAABHE
@>chr21:9890948-9891037-3
TCAGACGGTAATCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCAGTTTATTTGTCTGCT
+
EBACH@CAFG?DFADC?DAE?ADEB@@FBEC?D@GFA??IB?DCBI?DBIDBDB@BBAGE?CGADGDF?@DDBAGB?FEACFHGF*@AHCICIHHI??D?
@>chr21:9890948-9891037-4
TCAGACGGTNATCAGCAAATACATCATCCTTANATATNTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCT
+
CFCACGAGC5FIHEBGIHD@CC??AAAAIE@C<@HIF;AH?D?DFB@IAEEAAH?BDB@FEI@IEBGEBDGIB?FADACDFAAGADAAAIHCHHDFBIAC
@>chr21:9890948-9891037-5
TCAGACGGTAATCAGCAAATACATCATCCTTACATATGTTAATTACCTTCCAATTTCAAATTCTCAACTGTGAAATAAAGGGCCATTTTATTTGTCTGCT
+
CI?HDHBGE@FCEEIEIGG?I@CBABEEEBDFCC@EBAFFHEH?DFA@IE@AHB?GHAF?DEHCADGFCC?BECIFIHGBFEHD@A??@BEC?HFF?FBA
@>chr21:9894296-9894361-0
ACCACTATGTCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGAGTTGAGGGCTTTTATCTAAGATGCAGAGAGCGGAAGAGCGAAAAAAAAAAA
+
@EDBE?IIC???FE?FBBFFDBIABICCBCAI@I?ADG?CG@FBI?IICC?@?@FF?@GDC@@@DGE@GC??DHAC?B:@DBFCEHFEICAAHHI@GD?D
@>chr21:9894296-9894361-1
ACCACTATGTCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGAGTTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
A@EFDGCABFHBCH@?D@DA@A?@@CABFB?@B@GCHGDCH@EDDHGBIEBA?@EABCH?GF@AF?CHH?CIIIADFHFHH,HEFGBBBIAEIGEG@A@I
@>chr21:9894296-9894361-2
ACCACTATGTCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGAGTTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAAAAAAAAAA
+
?H?I?HDFDDHEHEDH?GDBF?HGDF@?FCHGD?@G?DDG??D?BFEIE?CGC@DCCEAAIDBFIEH?HEG?CDCCHEICEAG@HEFFE@A?FIHC@IED
@>chr21:9894296-9894361-3
ACCACTATGTCTGCATCTTAGATAAAAGCCCTCAACTCTGGCCTTCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
HGFBFDBF?IH?@GHB?AEHE@HBBI@BHBCDCFEGIGF@D-CH!?DGAIFB?AEAEGFDG@FACIF@IB0EF?HHDBDAAC@FE@CDAA?IFEEEDHFH
@>chr21:9894296-9894361-4
ACCACTATGTCTGCATCTTAGATAAAAGCCCTCAACTCTGGACTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
IE?DDACI@CCEEIH?B?GII?GE?CG@HDF?A??CBDC@A<AAGHIFBG?C@5IED?FDBFGIAAHBB?CGE@DCHFBBHCI@ICCDE@@FCHBB?EAG
@>chr21:9894296-9894361-5
ACCACTATGTCNGCATCTTAGATAAAAGCCCTCAACTCTGGCCTCCTGAAGTCAAGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
GCFEAF@?G@E(C?@HI?I?AHIBFH6A?ABIA?IGE@@HED@HEF?@HHFI@@;BDB?F?@HGCCC@GAAIHHE@G?DEFGFBGECIHCFG#??HIEAF
@>chr21:9894296-9894361-0
CTCATACCACGCAGCCAAGTTAAATGACAGCATCACTTCAGGAGGCCAGAGNTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAGAAAAAAA
+
@AIEGCABA@A@BAF?HEE?C?AEDFDHCFHFB;EE@CIC@CGECFH?HFG3IEBB@GI?G@B?CHDHCHIFDH?FBD@AADGCDBB?@EAF8CFAEIHE
@>chr21:9894296-9894361-1
CTCATACCACGCAGCCAAGTTAAATGACAGCAGGACTTCAGGAGGCCAGATTTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
FHBEGFDAACEIEFHAI@I?GCDE?E?HHADB4?HH@FFFFDGG?A@FGHAIHA?CBIC?E?A@G@EEBHGGIEDFC@@A@HAHIEBFAEABGIADEAC?
@>chr21:9894296-9894361-2
CTCATACCACGCAGCCAAGNTAAATGACAGCATGACTTCAGGAGGCCAAATTTGAGGGCTTTTATCTAAGATGCANAGATCGGAAGAGCGAAAAAAAAAA
+
AAGEEC@GAEICAIFHCBB+BHCDABC@?FBBDCI???FFABI@BC?A&AIF?@@@CE?FFBIFFBFHFCHI??F:FFEGCG@GFFCA?GEAIEDF?EHH
@>chr21:9894296-9894361-3
CTCATACCACGCTGCATCTTAGATAAAAGCCCTCAAATCTGGCCTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
DHAB@DGEA@BHCB?D@AHDBGICABDAC?IBC??FHF?@GDFIDE@CBBHDGGFCD@CCGBI@FEHBDH@GHHBG@FCCGIAAFDF@GBABFA@BCCDG
@>chr21:9894296-9894361-4
CTCATACCACGTTGCATCTTAGATAAAAGCCCTCAACTCTGGCCTCCTGAAGTGATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
BCB?IGIIIIG'D@DBFBICF?@DHGHEI@IBADC@?FHIHDCAF?CE@BABI9E?B@B@@GE?DACCFEED?@DGC?H?CCAFBIHHCDI@IEGCE?BG
@>chr21:9894296-9894361-5
CTCATACCACGCTGCATCTTAGATAAAAGCCCTCAACTCTGGCCTCCTGAAGTCATGCTGTCATATAACTTGGATGGGATCGGAAGCGCGAAAAAAAAAA
+
CIG?CABEBGCF?HGFFIDH?@?DH?ACIECDEBCDADGBEDABBGHCBEDC@FFD@CA?ACFC7A?@?EDCH<DG2C?CGEBFBE=FD@G@AHEGA@BD
@>chr21:9894296-9894361-0
GAAGGTCCTCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGAGTTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
HBAH@HFEGBDD?E?HHCEEG??@AGCGE?B?AA@GHD?E@EI@AEAFCAFIAIFCFIG@GF@FFICAGDAI?@FGGC@BGFAH@GDCHFFCCB?BA@?C
@>chr21:9894296-9894361-1
GAAGGTCCTCAGCCAAGTTAAATGACAGCATGACTTCAGGGGGCCAGATTTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAACGAAAAAAAAAAAA
+
?GF@EBAGBIEFFIEFA@EHGAICDHHEE?DFHID?@GDF"?EE?GAAFBAECBEE?I@EE@?F?HF??GA?CIA@F?FE@FCB?.EIICGBBAHGCFFH
@>chr21:9894296-9894361-2
GAAGGTCTTCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGATTTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAAAAAAAAACA
+
HGI?@DA"?H??F&?BADH?CG??GGBIE?E@CFFH@AIBFICD?FDIABIBADEFEHH@EFHAGBCCBHHBB??I?FFHDECEI@FCG?HI@AA@@G>B
@>chr21:9894296-9894361-3
GAAGGTCCTCTGCATCTTAGATAAAAGCCCTCAAATCTGGCCTCCTGAAGTCATGCTGTNATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
IF?I@ICCHGE?CE?GC?IHHHCEC@GG@C@CEDIAECFIC?EABDI@BD@DG?AF@AG+IB@?AHDAADFECIDAEB?G?B??GDCEGGGBDBIFD?B?
@>chr21:9894296-9894361-4
GAAGGTCCTCTGCATCTTAGATAAAAGCCCTCAACTCTTGCCTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
HI?HCFAFBHHFC@IAGIHAGAGEIIF?BBCAIGCFIB:FIACBBG@BF?GCD??CB?ICGGHE?H?BEGCHD@D@IG@IHAIEHFADGC@CHFEI@A@C
@>chr21:9894296-9894361-5
GAATGTCCTCTGCATCTTAGATAAAAGCCCTCAACTCTGGCCTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
HGC1DGGDHEC?@G?I?I?EGFI?EDAGCGDG?BGA@FAFCGDGG?HBBGH@E@I?D?HAHIHDCIB?HADI@FGF?AIEEIAEDA@C/HGIGA@FADGF
@>chr21:9894296-9894361-0
GCGGCGTACAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGAGTTGAGGGCTTTTATNAAAGATGCAGAGATAGGAAGAGCGAAAAAAAAAAAAA
+
D@AFB@AIHBAEEB@@G@E@CHBIC@GEBECCAFHB?IB@?C@DFGDDG@BA?C?AIIAB?B3(AAB?FEBACAAIG-HBAGHACEIHI?IIDF@I@?AD
@>chr21:9894296-9894361-1
GCGGCGTACAGCCAAGTTAAATGGCAGCATGACTTCAGGAGGCCAGATTTGAGGGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAAAAAGAAAAAA
+
H@@IECFB@FFAADDHGBDGFE?"?CGFAAA?HFE?ADEFFFB?GDBGDIDBF@CEABGAFH@@BHGDI@G?@EBFIA@ACG@ADDHAA??HC>DIE@H@
@>chr21:9894296-9894361-2
GCGGCGTACAGCCAAGTTAAATGACAGCANGACTTCAGGAGGCCAGATTTGAGTGCTTTTATCTAAGATGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
@?FA@CDBEGC@DEAAABIEF@IFDEDFH<FAHHHGGEC@AIGFICGFFFEG@6IF?@I@BEHICHBDCCBIDDA@EDCI@FHC@AIFC?GIH?I?F?H@
@>chr21:9894296-9894361-3
GCGGCGTACTCCATCTTAGATAAAAGCCCTAAAATCTGGCCTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
I?ECEDBCE?3HBDIB@CB@H@EFFFICEA8BHAECBIFBICDGGFBCEFCF@EBEFF?AF?DEIB?H?GICC?BIHDBD@@HG@DHDCDDCCII?BC@@
@>chr21:9894296-9894361-4
GCGGCTTACTGCATCTTAGATAAAAGCCCTCAACTCTGGCCTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCNGAAGAGCGAAAAAAAAAAAAA
+
CBEII/GFD?D@EGF@DDI?BFDBDHE?BIBHIDGIDDDI@DHAB?@@CF@EEIEGGIAGAC@EGCGAIBBIGABCG?&ABABCIAAF?@HIBICIF??A
@>chr21:9894296-9894361-5
GCGGCGTACTGCATCTTAGATCAAAGCCCTCAACTCTGGCCTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
CEG?F@CDF?@DF?FADADAA'HF?DA?H@FC@?BBGEEADICGDD?ECCCC@CICFCD@FHBAIHFBCHADCCDFD?EA@GCHBHDCEFD??HAFCD?@
@>chr21:9894296-9894361-0
TCAGACGGCCATCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGATTTGAGGGCTTTTATCTAAGATCCAGAGATCGGAAGAGCGAAAAAAAAA
+
GIBEFCAI$5@D??GGFFF??CEIC@E?HA@CDB@FAIICHBCEA?ABDEDGBAIG@EAEIHBFHFF@BDD?B#@?AFBCG@@A??DFHFAFHFABDGAD
@>chr21:9894296-9894361-1
TCAGACGGTAATCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGATATGGGGGCTTTTATCTAGGATGCAGAGATCGGAAGAGCGAAAAAAAAA
+
H?GDGAAICAGDCCC>CFDFBHAAAH??FC@EGFEIB@EF@F4EE?BC?IAA*EG"ECFCFEI?I7@AC6IBDCDIHCA?@D@?F??DI?DF@?DHHHD?
@>chr21:9894296-9894361-2
TCAGACGGTAATCAGCCAAGTTAAATGACAGCATGACTTCAGGAGGCCAGATTTGAGGGCTTTTATCTAAGATGCAGAGATCGGNAGAGCGAAAAAAAAA
+
H@ACE@GBDACE?GCII@FGC@EBCEDIGD@CGAGDHGCACFIE?HGG?GHGFDCACB?D@@ACIHGHHAI@?ABDH@GIECII.@CEEBCHIHBHABDH
@>chr21:9894296-9894361-3
CCAGACGGTAATCTGCATGTTTGATAAAAGCCCTCAAATCTGGCCNCCTGAAGTCATGCTGTCATTTAACTTGGCTNAGATCGGAAGAGCGAAAAAAAAA
+
>CIGBGEHBB?E?IGGHA6@F<H?@ABIBICGCIEG?EB?IFECA=FGGCG?DFD?IGGEA8?HGAEIIGBCHCHC4AID@CG@EEHHFFAABDH@BADH
@>chr21:9894296-9894361-4
TCAGACGGTAATCTGCATCTTAGATAAAAGCCCTCAAATCTGGCCTCCTGAAGTCATGCTGTCATTTAACTTGGCTGAGATCGGAAGAGCGAAAACAAAA
+
CEFGEAECHC@BGICDFHCCA?A?@?ACHEBFAF@C@IFAA?A@?FEGA?E@DFFGA@HF?DDG@GAAAA@?C@HGIADFBIIDECDGCGEE?AA>HEDI
@>chr21:9894296-9894361-5
TCAGACGGTAATCTGCATCTTAGATAAAAGCCCTCAAATCTGGCCTCCTGAAGTCATGCTGTGATTTAACTTGGCTGAGATCGGAAGAGCGAAAAAAAAA
+
BGEEGGCI@IIEG?ACIABCHD?FDCFBEFB@HFFHECBBA?A?CDI?F@IDDGBGBC?FA?8AIFGGDFHFFIC?ICHC@@IFIGAGBFADA@IE@IDC
@>chr21:9898936-9899065-0
ACCACTATGTCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTATTCATCTAGGAGCAGAATTGCTCAGATGCATATAACTGT
+
IEDHD?F@AGHIDC@H??AEEGHFHB?CCIEFBDFHEDFEE@DA?BA?FA???ICED?AC+BH*@ABHEH@HIHCACG?BDEBDIEF?FCCBEGEGE?CF
@>chr21:9898936-9899065-1
ACCACTATGTCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCATATAACTGT
+
EG?DB@A??B?ADBBCBGDC?AIDH?III@FAAD@@CAHDIICIHHIHFFAGIA@@GHFAEGBFEACEHHC@?BEFADCBDD??BBH@EHFCIHD?CIEC
@>chr21:9898936-9899065-2
ACCACTATGTCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCACATAACTGT
+
GG@BF@GIBIHHEFICBGCBIFAC?FHDEFAFBD?DHBBHB?BHACFIB@H@BBCDG?CFF@F?IEHFACIFEFHIHHF@BI@BECBABDF!I?@DEEDH
@>chr21:9898936-9899065-3
ACCACTATGTCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAAACAGTTATATGCATCTGAGCAATTCTGTTCCTAGATAAACACCGAAGACNA
+
GIFFCF?4AC@CDCDCEEAGAAFCBBBEGFADHFCF?FACAAFEGI@@?CA@C@?CCI@GF?DGFGBE?@?CGCC@)FGCAB@CABHFA?I@HAGE??2B
@>chr21:9898936-9899065-4
ACCACTATGTCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTANACAGTNANATGCATCTGAGCAATTCTGCTCCTAGATAAACACCGAAGACAA
+
FEAABE?FBIHCHG@GACCC?CABBIG?@F?C$HHHD@EEBBGGFHFF:A@GBA2F#GAF@FGBAEII@AE@D@E@@GEAHGGHIDEFAB@HCF@A@AAB
@>chr21:9898936-9899065-5
ACCACTATGTCAGCCATTTCAAAAAGTAGCTTGGCAGTTCCTCAATTAAACAGTTATATGCATCTGAGCAATTCTTCTCCTAGATAAACACCGAAGACAA
+
FE?EECEDI@HACDBG@EFIBCEBECIEB#??GGCIHBAIDHE@EB6HHGDB?GA?HA?A@ID@@BE@GG@EFGD6AAIIH?@?BEFC?BDBEHGG@IBA
@>chr21:9898936-9899065-0
CTCATACCNCGCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCATATAACTG
+
FDHIFEHD&@HDEGEGIACECF?CGFDC?IEEA?FB?AC@@EGDBGE?E@FBGGGCID?G?IFHCCECEEDDGCICGFFHIB@ACB?ECF/AFI@@@D?A
@>chr21:9898936-9899065-1
CTCATACCACGCTGCTATAAACATTGGTGTATAAGTCTTTGTGTAGATATTTNTCTTCGGTGTTTTTCTAGGAGCAGAATTGCTCAGATGCATATAACTG
+
FI@?DEB@IHIC?AB@BGEDB@ABEGH@IIE@@HGB.@@EGHBAICEIDF@B-+BGE?FAGD?DG'HBIHGHCCBAC??ADHDFBH@GEBACGFH@HHB?
@>chr21:9898936-9899065-2
CTCATACCACGCNACTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCATATAACTG
+
CHGGEE?IEHCA#%DA@E?BAB?@A?@DED??B?HCIEEAEIE@EAEIEBAIEE?DI?E@BBI@?F@IEI@GAF?DCEE?D?,A?HC@EBDHBD@ECG@B
@>chr21:9898936-9899065-3
CTCATACCACGCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAGGCAGTTATATGCATCTGAGCAATTCTGCTCCTAGAGAAACACCGAAGACA
+
FE?DHGAEH@AFIH@AHGFAD?GGBCI@IGEBHADBH@G@HIDCBEHGDI0BBF@CED@BAEIBGH@IFD@CAEFD@FI?F@FDA(B@GHHEHDE@A@CC
@>chr21:9898936-9899065-4
CTCATACCACGCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAGCCAGTTATATGCATCTGAGCAATTCTGCTCCTAGATAAACNCCGAAGACA
+
?IDCIG?@GBFB@CAGGHGAHCHC?DDEAF@AFDF@G?EDEFDDBHICAF!DGDCIH?FIHFEAD?HCACIFG?@?HBA@CH?AEFC@GH$A@B@AEA@D
@>chr21:9898936-9899065-5
CTCATACCACGCAGCCATTTCAAAAAGTAGTTTGGCAGTNCCTCAATTAGACAGTTATATGCATCTGAGCAATTCTGCTCCTAGATAAACACCGAAGACA
+
HBDFGEH?GDBCGA?HAGECGE@A@IE?CE@HIIIAIAD)HBGCHAD@HDIBBDC@I@GF?FBCHDCIBEHBGEDDC?BBACIBBD?DB?BHCFAIEBAG
@>chr21:9898936-9899065-0
GAAGGTCCTCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATAGTTGTCTTCGGTGTCTATCTAGGAGCAGAATTGCTCAGATGCATAGAACTGTA
+
FBCFCIAFAC?FIIGFA@HDAAAECCIIDDBDC?DD?BBFICAG?FA#EI?EGDD?AIIC?0GAG?E@ADI?AGGBHB?H@B?HABFG@CEI'A6EAAG#
@>chr21:9898936-9899065-1
GAAGGTCCTCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATGGCTCAGATGCATATAACTGTC
+
C?BFG?@HGDHFF?@B@CAG?IADF?DD???FECHFHBHAA@IB@@?DFBABI@GFAIHIDBB??ACCBAFE@A??HE-AHHIHA@?HDF?C@HCGGDBG
@>chr21:9898936-9899065-2
GAAGGTCCTCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCATATAACTGTC
+
GIEHIF@ACC@?IGGGFCDHF@CIEBEHGBCH?@?IBIGCBABG@BCHDBHC?FAG?D@HDADFFEIAGBCDH?CCI@EFDBGIA?BCH?GAHF@@C?BG
@>chr21:9898936-9899065-3
GAAGGTCCTCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAGACAGTTATATGCATCTGAGCAATTCTGCTCCTAGATAAACACCGAAGACAAA
+
GGFBCHIIEFECABHAH?IHGEDFGIIIFBDIBBA@DEEHAI@G@FIGB@CACF?I@DAHHFCBAHEFE?BIBDH@@DBBDHAGADDBDFIBDFFDBCEH
@>chr21:9898936-9899065-4
GAAGGTCCTCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAGACAGTTATANGCATCTGAGCAATTCTGCTCCTAGATACACACCGAAGACTAA
+
DI@G@BH@CHF@?EDGE@FBGE@ABHGCF<AG@C@GFC@DGFIEDI@?@EE@EDBFG4D?HEHE?CAGH?FBFHGIIGF@BA?HA<BD?CDDBEGAG;A@
@>chr21:9898936-9899065-5
GAAGGTCCTCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAGACAGTTATATGCATCTGAGCAATTCTGCTGCTAGATAAACACCGAAGACAAA
+
GFFIICCBIGHB@DF@HGIB@ACFIAHC?AICFHDICGE?AFBEHCFFE@HDGAFAAICADDBHCCFI?A?IBIGBC8ADADDDAFCDC?CC@ECEDDHA
@>chr21:9898936-9899065-0
GCGGCGTACTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATGTAGGAGCAGAATTGCTCAGATGCATATAACTGTTT
+
?IGBF@CG@HGEEHACAA?GA?@EG?GCBAIIEHAC@GAGCD@E?EB?BCDC?@HDEHCDAHED5CIGIIBBCGFFEBC@DFGHHDCFGGBFFI@FIIFB
@>chr21:9898936-9899065-1
GCGGCGTACTGGTATCAACATTNGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCATATAACTGTTT
+
BAFIAIGBABF%@?A<IEAEBC0DE@?EFDHAHI@DDIECGCHIABBADA?AEHHECHGE?@GAI?GG@FCI@A@CIHIAI@EAEI?@GDEF?BCBAFGF
@>chr21:9898936-9899065-2
GCGGCGTACTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTGTTTNTCTAGGAGCAGAATTGCTCAGATGCATATAACTGTTT
+
FD?C@?ECABFGGE@DEAHFG@CEFA?B?CII@@GGIGHE??CDFCADBBBIDFC?ECIGII<HFH?IG?AAGGH?F?DDFAI@C?BHIC@CDGE?@D?C
@>chr21:9898936-9899065-3
GCGGCGTACAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAAACAGTTATATGCATCTGAGCAATTCTGCTCCTAGATAAACACCGACGACAAAT
+
IF@C?@EFDIBHAD@CHB??FFABGIIA?CEFBA@AHGEE?6?EBAIFAAHDHEAHHBAHBAAEHGDAHAEHBH@?AIADDBDC?GGADBEC3H@AAIEE
@>chr21:9898936-9899065-4
GCGGCGTACAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAAACAGTTATATGCATCTGAGCAATTCTGCTCCTAGATAAACACCGAAGACAAAT
+
HD?B?DFF@HFED@HIA@GEGBD?@GDFIEHF?EDCAFGE?GHBCID@EBBHCHDBE??DFEDAIBFCICHH@FHFBCBIDIC@DCADACHFCB??BI@G
@>chr21:9898936-9899065-5
GCGGCGTACAGCCATTTCAAAAAGTAGTTTGGCAGGTCCTCAATTAAACAGTTATATGCATCTGAGCAATTCTGCTCTTAGATAAACACCGAAGACAAAT
+
AGB?@A@IFCFDD?G@H@DHHA??HBHHIDD@@?D-BAC?HB@IEACFCCAGFHAFG@ABGIECHEIBG@CHEG?CA'@DCEBFHBABH?FHIFEIAGDD
@>chr21:9898936-9899065-0
TCAGACGGTAATCTGCTATAAACATTGGTGTATAAGTTATTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCATATAACT
+
AD?@FHE@@CICCHDDGD@DDI?BIF?@@AE@AE?ACD>B@AGDIBIDCEFG?HHGIGF?GF@HIEC?DEGFFGG?F@BGDHDABADGEDB@HADECGFE
@>chr21:9898936-9899065-1
TCAGACGGTAATCTGCTATAAACATTGGTGTATAAGTTTTTGTGTAGATATTTGTCTTCGGTNTTTATCTAGGAGCAGAATTGCTCAGATGCATATAACT
+
DB??FEHHGIAIEFID@AGBDD?GDCDDGGFDBG?DCDDD?IBEC@BDBIABB@AEEEGC@B1@EHEDG@B@CID@@?-?EGICFDIGEG?DG?D@HII@
@>chr21:9898936-9899065-2
TCAGACGGTAATCTGCTATAAACATTGGTGTATAAGTCTTTGTGTAGATATTTGTCTTCGGTGTTTATCTAGGAGCAGAATTGCTCAGATGCAAATAACT
+
H@GFCGH@A?4D?FDADIFEAHCBACABBA?@GDBAC=EEGAG?BD?@FCD?A?@FGAEGEDAAEH?@CE@C?IFIEEBB?H@HDI@CA?HHI*IDCB@A
@>chr21:9898936-9899065-3
TCTGACGGTAATCAGCNATTTCAAAAGGTAGTTTGGCAGTTCCTCTATTAAACAGTTTTATGCATCTGAGCAATTCTGCTCCTAGATAAACACCGAAGAC
+
BH%HID@G?@F?EEHA0AFI?BD?@?%@ECGI@FCE@@DDF?B?I:DFIIAGDBAI?:F@IADICC??HIDDB?@EF@ID?IDCAF@CFDE@FDCBCCHC
@>chr21:9898936-9899065-4
TCAGACGGTAATCAGCCATTTCAAAAAGTAGTTTGGCAGTTCCTCAATTAAACAGTTATATGCATCTGAGCAATTCTGCTCCTAGATAAACACCGAAGAC
+
CABB?BGHDEDI@AFHCHAHHBGGHIHFHFCE?A@A@?GGDCFBICEHI@FGHB@BEAECEA?CHIIEFHHFEGAGEDAA?EHAFA@DA?D@GDIDHBCI
@>chr21:9898936-9899065-5
TCAGANGGTAATCAGCCATTTCAAAAAGCAGTTTGGCAGTTCCTCAATTAAAGAGTTCTATGCATGTGAGCAATTCTGCTCCTAGATAAACACCGAAGAC
+
DEGEA.EF?@G?DDD?AFAIHCGFHA@H%BIHAG?A@AFE?GAEDIA?B@EI.CHDE%H??B?F@-IHHGEIACDCDGAHBCA?HD?GCF@CEAGGEHDI
@>chr21:9902581-9902737-0
ACCACTATGTCTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAACGC
+
FEHG?HFHCFIH@BI?@AB@@DDIGIHI?DABEFABBH@CHF?CAGBEDBFDF@B?CDAACAFEGDDICGCG?FA<IHEGCGEG@?BDH@?DGCACF??G
@>chr21:9902581-9902737-1
ACCACTATGTCTGCTGTAGTGATGGCTTATGACATCAGGAATTTACTCTCTCAAAGTTCTGGAGGCCACAAATCCAAAATCAAGGTGTGGGCAGAAACGC
+
C@@BI@FICEI?BBICC@DAFBC@?EDHEGIGBFHIDIIGFDCAE,GDA?@BA#EFGAIIGCEDIDACECH:BDICIAAIGCBBGFG?BFI@BDGHHIEE
@>chr21:9902581-9902737-2
ACCACTATGTCTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAACGC
+
@CEFHG@EADICFDEEDB?HG@HH@BIIBHBC@CFDAFFFEGAGEEEGEBAABDG@F@FCIEEADIADBCBFFFC@DH?@IB?EFEHACEI@A@?HB@AA
@>chr21:9902581-9902737-3
ACCACTATGTCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGGAGAGGGAGCGCGTTTCTGCCCACACCTTGATTT
+
H?EGHDEGCEAAGEBCFIFAEE@?HFC?H?GHHBDE@CB@EAGEAEECCFAG?C?EEEBDEBED@?8FIC?EFC@BAIC?GIE@DHBDHG?@E?DFAHBE
@>chr21:9902581-9902737-4
ACCACTATGTCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGATGGAGCGCGTTTCTGCCCACACCTTGATNT
+
@F@E@ABE@FHGBAIBDCB?@?@C@HDD?CF?FGCCCFAGFGEHEA@ICHIIHF@?A?DBCCGBAFFFFF%ECBI@?@BBCHGACCFAGGFAF@@GAB7I
@>chr21:9902581-9902737-5
ACCACTATGTCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAAGAAGCATCCTCCCCAGGACTCTGCAGAGGGAGCGCGTTTCTGCCCACACCTTGATTT
+
ECIB@BD?@DGCEFEADHAADFB@@BIAC?E@@BGHHCAEGGD6@BCFDCIF?DA?CGB@D)?IIG@AI@HIEHCBFBIGCGH@ABAHCF@@BDIDBCHB
@>chr21:9902581-9902737-0
CTCATACCACGCTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAACG
+
AI?GDGFBEH@FEBIHHCA?EGIBH@AA@?HIDEBFACCCIDGE@BIDHDFCCEBA?D@BHD@AACDA@BCID?B?I?BEI@FH?IEDAHB@AGHEIEHD
@>chr21:9902581-9902737-1
CTCATACCACGCTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTAGAGGCCACAAGTCCAAGATCAAGGTGTGGGCAGAAANA
+
HIG@BHHFC?GHGH?BD@BHAEBHHCHAGIHC@@EEGBDD@CG?FAGFGAA@*FHGCGEE?6ACCIFH?HGHDD@GGB4EAGHHE??BECIGCDGH@E>*
@>chr21:9902581-9902737-2
CTCATACCCCGCTACTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAATG
+
AHCAFFGH!AIG?"HA?DCDHFCA?B?EBGIBDAFGBD?G@BE@B?@IFHGC?II?B@IFB?D@EECC@F@IH@AICA?@AEB?A@ABA?@E??EHDIC?
@>chr21:9902581-9902737-3
CTCATACCACGCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCTGAGGGAGCGCATTTCTGCCCACACCTTGATT
+
HEGDF@DGCBBBFG??FFB?@?IEA?HBA?FDGBEII?DG@C?CDD@?IBHIA?BCIEHDIH?G?ACC>GFFFBAECII@AEBIC?EHIFI??A?E@DE?
@>chr21:9902581-9902737-4
CTCATACCACGCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGAGGGAGCGCGTTTCTGCCCACACCTTGATT
+
ICHGBIIEAC@C?EDDGBE@?ECD??H@C?CDBEH?EHFDIHBCI@EHFHIECDDHABFDDADCEBDD@F@AIACH?GFHEDHGI@ADHBCH@FH??CDB
@>chr21:9902581-9902737-5
CTCATACCACGCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGAGGGAGCGCGTTTCTGCCCACACCTTGATT
+
@@ACICAACE@H?CEECECIB@HEGGC?G?BDABHCCGBHB@???DE?G@DDD?@BH@@H@?D@@E@AGA@@DIAFGEBFG?H?@GGF?BIE@DHCFB?@
@>chr21:9902581-9902737-0
GAAGGTCCTCTGCTGTAGTGACGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAGTCAAGGTGTGGGCAGAAACGCG
+
AFEBDFI@GFBCD?GFHIFAH0FAIDGCCBIGAFIHHFBFEDCCDGH?F?@I?HCF@C?ECE?IID?GCB?CDCECA0IEDE?H?C@D?D?ABA@HEIFA
@>chr21:9902581-9902737-1
GAAGGTCCCCNGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTGACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAACGCG
+
E@EADICH;C-AACADEE@AGC@DEFIEFCEDIGDICFDCBFGAEF?GAH"BDIGGEHIBI@@?ABIBCCGIBIF?BIFEECDEDFCDCGG@BHA?CHH?
@>chr21:9902581-9902737-2
GAAGGTCCTCTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAACGCG
+
AEEIEEHD?GHIBCAEDHBB@@GF?DD@BEGD@IH@ACAHAE@ADACGDDDGHIDH@H?@HI@DGCBIHAAH@IHADA?AEDEEEBH@HEGCGIDDEG?D
@>chr21:9902581-9902737-3
GAAGGTCCTCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGAGGGAGCGCGTTTCTGCCCACACCTTGATTTT
+
@E@?HA?IAIGAHGEC@BGII?@GBAFAECD@G?I?FAFHBH@FHIHC@CHCAE@@EHFCEIEE?@GADHID?@?AD?EIFCDIHCHGF@DGAIDIEABA
@>chr21:9902581-9902737-4
GAAGGTCCTCTGCAGGCACCACAGTCGAAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGAGGGAGCGCGTTTCTGCCCACACCTTGATTTT
+
HIHCED@AF@IE?HHDG@IHH?IHHFD3EBHCFCGEIF?BDA?EHCFC@CCIEEACDBFIG@F@FIE@EDG@G?AF@HC??EACECDEIGDHHCAHDIF?
@>chr21:9902581-9902737-5
GAAGGTCCTCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGAGGGAGCGCGTTTCTGCCCACACCTTGATTTT
+
CA@FB?IBGBAEAEH?@@?EH@AH?DIEIAA?B?A?AFAIIIFCCBAFFHAGBBII%CH=IFF@HD?BFDFC@@FHAAI?BDF@CCFFCB@G?HIH?@CI
@>chr21:9902581-9902737-0
GCGGCGTACTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAATGCGC
+
I@HAFEF?EIH?ECEB?FCGIGC?A@D@CIBFAH@IEB?GBAEA?GAGCAFGB?GBD@CHIHIDH@HI??EFIFG@DEAG@CGH?@CGEBGFDCAIAI@A
@>chr21:9902581-9902737-1
GCGGCGTACTGCTGTAGTGATGGCTTATGACATCAGGAGTTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTNGCGAGAAATGCGC
+
ICBEIDDHAIIEE?DICICEC@A@AIEFB*C@F.AG@I3CD?@FHEBFDDGHICBICGIHGB?FCG?FH@E?HFIIFGBCHF@FEF<F,9CCD?ECFBHH
@>chr21:9902581-9902737-2
GCGGCGTACTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCACGGTGTGGGCAGAAATGCGC
+
GH?CAIF@IIGGDEF?ABC,G?CA?D?IAIG@AIHH?FEIDGGDDIAIIG?HCG?FEBHAG@D@BE@IGAA?AI@B@GBB>IGBBGCHHF?HCDIFDDDI
@>chr21:9902581-9902737-3
GCGGCGTACTGCAGGCACCACAGTNGCAGAGCTGGAAGAAACAAGCATGCTCCCCAGGAGTTTGCAGAGGGAGCGCATTTCTGCCCACACCTTGATTTTG
+
AIEDD??@F?BHDFIFFEI?DBD@>E?I@D@GGH?@@AIEBFBF?CEI,IEEFBDGDDCHG9@@CGABIBHIADCDAEBABFEGCIGBI?ABCCBBFAID
@>chr21:9902581-9902737-4
GCGGCTTACTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCATAGGGAGCGCATTTCTGCCCACACCTTGATTTTG
+
HBGGD6H?D?DDCDDC@@GHAFE?FDDEFFCHGIAFEIG??BBFAI@HHECHGADDBCBI?@GDDF/GA?HEGHHIGGFABEAGHIHEAFIBF?FAH?DD
@>chr21:9902581-9902737-5
GCGGCGTACTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGAGGGAGCGCATTTCTGCCCACACCTTGATTTTG
+
@B@BIFHGCA?HG@EDECDAH@HIAGGIH@HIHCGDFHBCBABIBEBGBCFHEBDG@GEFIAE?FHAADEIHBHAHB?DHAEBD?ABECAB?DAECAIB?
@>chr21:9902581-9902737-0
TCAGACGGTAATCTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCTCACAGTTCTGGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAAT
+
EIEAEGFAFIBAIFC%GACIGI@@AGECH@AHA@D=DAFC@DD@EBFIA+D@CCCBHHGHCBBCBCG?BDEIBDIAF@@AACEACC@ACD?D@IIHIEDC
@>chr21:9902581-9902737-1
TCAGACGGTAATCTGCTGTAGTGATGGCTTATGACATCAGGAATTTATTCTCGCACAGTTCTGGAGGCCACAAATCCAAAATCAAGGTGTGGGCAGAAAT
+
BEAAAH??HGAGGH?ADDH@CBIDI@BHICIDFECIIFG@GDGCCAI@@I@C'AGFC??@G@EBC?@AFEE@I4GGF?BFA@EBGACHIFHFBH@?GDDG
@>chr21:9902581-9902737-2
TCAGACGGTAATCTGCTGTAGTGNTGGCTTATGACATCAGGAAATTATTCTCTCACAGTTCTNGAGGCCACAAGTCCAAAATCAAGGTGTGGGCAGAAAT
+
GEECDGDGGF?9B?F?IEAGDA@"CCEGIGIEFEIBIIDBHF@7CI@@@CED?IBCAADEFG,?GEEF?@FCIGACHABGFBCGCFDEADFGGCGEA?DI
@>chr21:9902581-9902737-3
TCAGACGGTAATCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCAGGAGTCTGCAGAGGGACCGCATTTCTGCCCACACCTTGAT
+
F)@GC@EGEF@DEF?GDFEH@FEDGI?CBEFFHAHBBCII@DHICAIF?@BDCBIDAI@CFDF@?DDBFEGBFHE@;A?D@DDFF@?EF@IDCHCA@G?C
@>chr21:9902581-9902737-4
TCAGACGGTAATCTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCATCCTCCCCATGAGTCTGCAGAGGGAGCGNATTTCTGCCCACACCTTGAT
+
GEFEAEBGF@EA@A@BGFECBGIEDII@I?GHHEBFIC?HIGIFFCIIGD?C,AEAEDBH3I@DID?GIHGEB@HDGBA$GHG?DI?CE@FIHCEIGG?D
@>chr21:9902581-9902737-5
TCAGACGGTAATNTGCAGGCACCACAGTCGCAGAGCTGGAAGAAACAAGCGTCCTCCCCAGGAGTCTGCAGAGGGAGCGCGTTTCTGCCCACACCTTGAT
+
EBD?IA@DHHD@#GGD@GFIHDEE?@@?HBFDBF?ECDBGBEHHE?DBGF>A?@GAFECDFDGCEGBB@I?HBBIFDG?I"FEAAIHGAF?GFG@GCIE?
@>chr21:9902734-9902802-0
ACCACTATGTCAGCCATTGGAACCAGCGCTGCACGGCTCATACCTGGGTGATGAGGCCACAGCTTTTCAGGTGGGCAGAGATCAGAAGAGCGAAAAAAAA
+
BC?GGCECG@A@FDIDHHEIA*HIFAF5CE@?B@?BAEFE%BEADHA?DGGFDD?A'D?DBDGCDG)EGCFAIGB@CEEE@C@#@D@GDGFD?FABFF?D
@>chr21:9902734-9902802-1
ACCACTATGTCAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACCCAGCTTTGCAGGTGGGCAGAGATCGGAAGAGCGAAAAAAAA
+
?HGFGHIAEII?H@BDFGGAB?DIDHBEIHHAHCD@GFH@F@BGDCFHAAABB@GA@C'HAFC@FGCID??A?AFHHIBD?HDIAFAHDFI?ECFE@@CE
@>chr21:9902734-9902802-2
ACCACTATGTCAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACANCTTTGCAGGTGGGCAGAGATCCGAAGAGCGAAAAAAAA
+
E??ADAIE@EE?F@DG?ECA)@EIGAHB@CDAIBGAGI@@G?CBHDGFE?EAAICIFHCB?'FG?E?G?GAD??BDEAFGBCE/EC?HHHBIEBA@A?GD
@>chr21:9902734-9902802-3
ACCACTATGTCTCNCCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGTAAAAAAA
+
ADIGIAIBEIIE9'DIHHAGIAI)HAEEF?B@HF?BIIHGDBBFF@@B?HB?AHHDBCDDEGEBA??ADFIGEBHAACCCEHB?CAADGHGF$BA?@G?E
@>chr21:9902734-9902802-4
ACCACTATGTCTGCCCACCTGCAAAGCCGTGTCCTCATCACCCAGGTCTCAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAAAA
+
?H@E@ABCFHBGI?H@CEB@HGBBFEC=ICFIEGEIEIEC?DHAIDB?H<GEG@?AIC?HFCD??G@??@CHFAHCECF@BDF?F?HEFBADDBH@?ABI
@>chr21:9902734-9902802-5
ACCACTATGTCTGCCCACCTGCAAGGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAAAA
+
?EEBAFICHCIADHEBFH?@HIEE>HDG?EBE@?@BIGA?HCB?DDE?IC?CGIEBHGAHFIG@CAACAHD@HFE@@H?EIAH@EEIEGACHDHIIIHCF
@>chr21:9902734-9902802-0
CTCATACCACGCAGCCATTGGATCCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACAGCTTTGCAGGTCGGCAGAGATCGGTAGAGCGAAAAAAA
+
FHIAHBAGBHACIFBD@?CIGG%AHGBAFE@C@?A@A?E@@BA?AAIECB@GBHEB?EGDD@ABIIF@BB?IF@DEF?@G?EIHIC*@@EEHICIBB@AA
@>chr21:9902734-9902802-1
CTCATACCACGCAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACAGCTTTGCAGGTGGGCAGAGATCTGAAGAGCGAAAAAAA
+
HBHI?CFFDEC@BCGFDIEI?G@BAH@D?ADGADADEAADHCBHDAHIBIEDDEI?C@BCCDHDGH@CEBDIIDCEAAA@?IFC4?A@B?GCDBBDHEHD
@>chr21:9902734-9902802-2
CTCTTACCACGCAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACAGCTTTGCAGGTGGGCAGAGATCGGAAGAGCGAAAAAAA
+
ECA<BHC@DHI?F?CIDDAFF@HAHHCIAHH???BBDGI@AD?BHID@?FHA@I@DHCABHEGC?BFF@:@IAGB?@BD@?C@E@ID?CGAABFEIBC?A
@>chr21:9902734-9902802-3
CTCATACCTCGCTGACCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCTGAGCTGGTTCCAATGGCTGAGATCGGAAGAACGAAAAAAA
+
I?GDGEHE=?GAHD3AIEHCDA?AI?HC@@DGD?GEEEC?IDIBE@ED?C@IIE??GDA;DBD@IFG?FFFCCB?BC?AIEB??DCIIGB1ICCDAAGEG
@>chr21:9902734-9902802-4
CTCATACCACGCTGCCGACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGGGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAAA
+
B@G@A?A???@EIADEACED@EHIIDBABACF?@E?#HEDCHGFB?@B?@F?FBG@@GB?B>BEHCD?EAHFDA??DIDG@@GEF?C;GCAFAIFB?IDC
@>chr21:9902734-9902802-5
CTCATACCACGCTGCCGACCTGCANAGCTGTGCCCTCATCACCCAGGTCTGAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATGGGAAGAGCGAAAAAAA
+
BFC?FFCIAGH@IFE?E?@HCEFH0GAI?FD?9H?GGEBEA?G@EIHCHEECA@C@D5E??HEIEIA@EGDGDEGD?CIB??C'FDDGGEHHG@GFGHDB
@>chr21:9902734-9902802-0
GAAGGTCCTCAGCCATTAGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACAGCTTTGCAGGTGGTCAGAGATCGGAAGAGCGAAAAAAAAA
+
C?I?@ID?HFCEFE?DG;?@@DFHHIC@=?I?@AGAGEG@BHEFBC@ABDD@D@CBIIEDDAFHGHD?AABEC:GBFHAI?FACAGCFIGDIE@IB@BAC
@>chr21:9902734-9902802-1
GAAGGTNCTCAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTAATGAGGACACAGCTTTGCAGGTGGGCAGAGATCGGAAGAGCGAAAAAAAAA
+
A@IFDI(HDDEDDEIA?FCE?CGGBGGF@GIF?DCGFHDE@AB?@CB?1FAGIEIHFICDIID@DC?AF?IA?GAGB!HFFCEIADAC@GGBEB@B@E?G
@>chr21:9902734-9902802-2
GAAGGTCCTCAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACAGCTTTGCAGGTGGGCAGAGATCGGAAGAGCGAAAAAAAAA
+
BDBFDIGI@?HGFDHEIBCBEGA@BAAFF?C?EDDFEBFBEDHCADAHHFFDIGIBFFIF?BD@AFBFCHDB@F?DFEF?F@BGF?HAEBAEGECAIFB@
@>chr21:9902734-9902802-3
GAAGGTCCTCTGCCCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCCTGCAGAGCTGGTTCCAATGGCTGAGATCAGAAGTGCGAAAAAAAAA
+
FA?DID@C@AAAHC@A@@H?FCGFIDIFAHEF@G?BIFA@DHGFIDEDHIH@A7GHB?IB@HDIAEAI"HFI?BFEH?DDAA#AII@(AFDEEAHDACAH
@>chr21:9902734-9902802-4
GAAGGTCCTCTGCCCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAAAAA
+
F@FGDFGEABCGDI@FC@@E?G?@IA@F?GHIG?AACIH@GDBCC??FDF?DGBAAEHIE?A?@CDHCAEGHIEH@FDBGEEDEHHB?@HCDHHIBEIBG
@>chr21:9902734-9902802-5
GAAGGTCCTCTGCCCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGAGCTGGTTCCAGTGGCTGAGATCGGAAGAGCGAAAAAAAAA
+
BEECHFEC?@DDD@ABAAC?GED@IAD@FIBFAGEBEH?B?@GCAID??EFICI??BA?GCH@CF??B@D>IFDHAECGHAGCHACA@EIGBFH?@E@EA
@>chr21:9902734-9902802-0
GCAGGGTGCAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACAGCTTTGCAGGTGGTCAGAGATCGGAAGAGCGAAAAACAAAA
+
?@,F5?A!?AFCACGA?IHEBDG?CHAG@DBEAG?@FAICIB@CHG@BIGCDA?E?A@GBDDB@IDAICADG2??CG?HD@@F?IBBG@IGBHH@+@DCD
@>chr21:9902734-9902802-1
GCGGCGTACAGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACTCAGCTTNGCNGGTGGGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
@GE?ED@????AIAIG@IIFADCB??FDD?E?HAIDGDFCI??C?CCC?A@D?A@G+F@CFIE5D@&G@EIA?AHI@BEACD?DI@HGHBEI@B@CFGBC
@>chr21:9902734-9902802-2
GCGGCGTACAGCCATTGGAACGAGCTCTGCACGGCTCAGACCTGGGTGATGAGGACACAGCTTTGCAGGTGGGCAGAGATCGGAAGAGCGAAAAAAAAAA
+
GEBIBECHEI@GCIGDGBIFF)FA?HGF?IDCG@B?BEBHBA?G@BEHIIDBGEEIID??G?BEFFB@?GB@G@DCAB@GA@BBEA@DCI?IEHIF@FFD
@>chr21:9902734-9902802-3
GCGGCGTACTGCCCAGCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCNTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAACAAAA
+
??HIIFG@DGDCDEA;BG?CAD?@EF@?BGEEI@@DDFI?FG@HCIHCC???-?CFDDBI?GBCGHBH@GHG@DEG?G@G?GACHDFBI@CI@H?5HE@D
@>chr21:9902734-9902802-4
GCGGCGTACTGCCCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGAACTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
F?BA@HHC@BEDD@ACCDEAH?HBIIGCIHEECAEH@HFBD?BF??BGAGG6IAE?C??1@DB?H??@@H@F?GGCFA@@GCCEHD@EEEAG@F=CFIG@
@>chr21:9902734-9902802-5
GCGGCGTACTGCCCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
B@EEGEFEDCHDAAECEEC?@AA?D?GBDCGHEDH?CA?DDBF@EGEB@IEHEHADFE?EFDGA?AGEH??BAGAEGBGGDD@CEHIGDDDH@H?A@C@E
@>chr21:9902734-9902802-0
TCAGACGGTAATCAGCCATTGGAACCAGCTCTGCACGGCTCACACCTGGGTGATGAGGACACAGCTTTGCAGGTCGGCAGAGATCGGAANAGCGAAAAAA
+
IIEGFGHEEIICCF?FDHE?IA?@AA@CHBHBIGBECFIFC@"IDA@@FD?CB@CDBH?@E?EEI?BDBEIAHAGFHCFEEG@DD?IBE-?GIEAFDGC?
@>chr21:9902734-9902802-1
TCAGACGGTAATCAGCCATTGGAACCAGCTCTGCACGGCACAGACCTGGGTGATGAGGACACAGCTTTGCAGATGGGCAGAGATCGGAAGAGCGAAAAAA
+
EDIGGBC@HGCGBHBHG??@HA?BAC?HDCIIDIIEGB@<A@B@GFAB@GC@FBBGDGA?@ECBBAH@G@?C;DCHHGED@CCCCFEAAEAFDDBCDE@@
@>chr21:9902734-9902802-2
TCAGACGGTAGTCTGCCATTGGAACCAGCTCTGCACGGCTCAGACCTGGGTGATTAGGACACAGCTTTGCAGGTGGGCAGAGATCGGAAGAGCGAAAAAA
+
HI@I@@?@GE;EA%BCBH?DFAG?BCDABBHCICGFFIDGFFCGBIDDDBHFBH$HIGEHDDBBGDI??CIFGAC@HEFBBCGHBD@BFABHDCIIGABF
@>chr21:9902734-9902802-3
TCAGACGGTAATCTGCCCACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGNGCCGTGCAGCGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAA
+
CFCIGBGHAE@@EFEDBHCBE@CIDIC?@FHDBAB@ID@@AGEII@FIIC?G/B?B@IG?BF,A@@@?D@GF?A?BICCAFBGCH?HFIAFDHAIAE@?C
@>chr21:9902734-9902802-4
TCAGACGGTAATCTGCCGACCTGCAAAGCTGTGTCCTCATCACCCAGGTCTGAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAA
+
FC?FCAHBBEGIEDCC?HI@DGIBF@?BG@DFFCDEBIFGDBHDF@CDEAGGGH?FEHFDE@BGH@GFCFEDCAF8A@?FCEIHI??IIEDGA?F??CEB
@>chr21:9902734-9902802-5
TCAGACGGTAATCTGCCGNCCTGCAAAGCTGTGTCCTCATCACCCTGGTCTGAGCCGTGCAGAGCTGGTTCCAATGGCTGAGATCGGAAGAGCGAAAAAA
+
IBF@?FC?ECDBAE@CHE8A@AGAIECGEB@@?FGIF?A?@C???'CCHEFDGFF?CCFIBBCAHHAHB?EIBIHEDI@FDIAAGG?A@?GGIBEF?A@C
@>chr21:9902799-9902929-0
ACCACTATGTCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCCGAGCTCCTGG
+
AHAIECHHBHEFDFDGAED@DCI@EHF?HFB?@G?G@B?@FCDEAGFGBD@BIIH@BCGDGEEGDEGAIIEB@ABHH@ECHHDEAA?DD7BHCID@GFEC
@>chr21:9902799-9902929-1
ACCACTATGTCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGACCCTGAGCTCCTGG
+
IFGFBI@C??IHG@BGABGIIBAG?EAEIEH?AED?IC?AGF?A@ECEDCFCDE?FCIBCDGAE@BE?@FID@@BBI?BIAADHB=FBIE?GD??@@HD?
@>chr21:9902799-9902929-2
ACCACTATGTCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCTGAGCTCCTGG
+
GHBBCIICDIHDG?BD@@HABBFGDCEHIDIF?DFG?IC@IAAIEHCC?@ACG@AFAGBFEC?CBEG??DE?AHA&IAGF?ICIEDGHDCCCFCEBHG@I
@>chr21:9902799-9902929-3
ANCACTATGTCTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGCCAACAATGGGGAGCCCCTGCACAGGTTGCCCCAAC
+
B!CBCIEAGAEACCCAIC?IGIF@HD?BDDCA@?FC@BCACGH?FGHGEHAC@IGBI@EAFDCI;HCCGBGHHGFFI@G@DFECAHG.EIIA?I@AH)FA
@>chr21:9902799-9902929-4
ACCACTATGTCTGCAGTATNTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCTAC
+
HE?@HHEGFA?@?EHH?G?1FCDFI@ACAGDCDCE?DAIHFCB@FHIGHFFCADHI@EEH@FCHABH?CGH?GH@B@E??CCH?@H@A@IEIIEIEEAHD
@>chr21:9902799-9902929-5
ACCACTATGTCTGGAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCTAA
+
HEEG?AACDDBF?7G?CGDFA@FB?@BEBAIBEAICDHBFIACEBCA@EDGGBGGFECAGFCBH@ICFE@F?HDHGE@CBCDDFI@HDDIIA@FEBCIG'
@>chr21:9902799-9902929-0
CTCATACCACGCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCTGAGCTCCTG
+
IBB@BDEDEBHIFAIAH@BEGHFDIACBADBAFCCIBG@@?ABIDIA@EBAEIEBGE@FCE@A?IDBEIGE@?CECCCAIE?DH@G@IHIHBDFFDAECD
@>chr21:9902799-9902929-1
CTCATACCACGCAGCGACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCCACCAGTGCAGGGGCTCCCCATTGGTGCCCCTGAGCTACTG
+
FHCBA?AA?B@@F?F&DCG?BDFCCI@@BII@B@?IDEBCIAIFBBGDDBE?EAGBEDF2AHAHFEBBEBCCBIID??D@@ED9GFF?I#ICBIE?2GBG
@>chr21:9902799-9902929-2
CTCATACCACGCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCAACCTGTGCAGGGGATCCCCATTATTGCCCCTGAGCTCCCG
+
?EFFDBHBFB?AIGD?HC?GB?GE?CDDFC@HCCEFCCB@CEAGEHBBGI?F?FIEHBHAF?H*HG?DED?IB*E?AIEIGC.B@DCI@IBE?FII?C*H
@>chr21:9902799-9902929-3
CTCATACCNCGCTGCAGTATGTGTGCANCCACTTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCTA
+
?EBFHD@E7EAFDICEG@C?GD@?H@C>?IA@4IFE@E@I@?CGFB?IF@FB@DIFGIFA?HGIDEECABGAHFGGDHICEIHEFDGDDI@@@ID?H@?G
@>chr21:9902799-9902929-4
CTCATACCACGCTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCTA
+
?A?CIEH@??GBBCDDECAC@BEBBFGHED'EBDIH?HEFH@FE@HDIH@I?GI@E@DCIF@DGH?D?FGCC?BEE?DCD?DED@AD@I@CBHGCAGF@@
@>chr21:9902799-9902929-5
CTCATACCACGCTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCTCTGGTTGCCCCTA
+
IAFIDCCDCH?BD@DHFDBCIAAECFCDAECCHFCE?DBCGHEH@C@F?BBECFHDGEABC?EC@AHIDBB@FAI??HBHCGFGIC6ACCFFDEI?BHEI
@>chr21:9902799-9902929-0
GAAGGTCCTCAACCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGGGTAGGGGCAACCAGTGCAGCGGCTCCCCATTGTTGCCCCTGAGCTCCTGGG
+
GCGI@EBBDBE2IH@@CCBGBCFIBBDGHCEDIB@FAABICFDHG@@HBDHA??FDIB@C?ABA?FEH1CBBDBFECGFFAIHDECAIH@HEEFFE@GHG
@>chr21:9902799-9902929-1
GAAGGTCCTCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGGGTAGGGGCAACCAGTGCATGGGCTCCCCATTGTTGCCCCTGAGCTCCTGGG
+
?A@A?@A?H@DAA?GHEGHE?FFIBGGDIB@FICEG?DBAH?EF?F?DDI?@2EEDE@GBAB@CGEF&FHHBHF@?HBBEFBDEDGHI??CGHFAFD@AE
@>chr21:9902799-9902929-2
GNAGGTCCTCAACCACATCCCCAGGGGGNGACTNTGGGCCTGTGGCAGGGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCTGAGCTCCTGGG
+
B;@CB?G?IDB'BGDE@GBC?FCGB@FG/HEFG/DD@?DCD??HB@IFBIDIBHD?DEGD?CE@DE@B?EDECHBHFHGHIHBDIDHC?B@E?I@IGDAF
@>chr21:9902799-9902929-3
GAAGGTCCTCTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAACCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCTACC
+
FEDE?DFBEB@BDBFDBE?DCB@FHCGG?FFBEE@BD0DAA?BEAE.C?D@IHE@AGCIHHAHAEFFA@A@FHHEBAIIBBGFEHC?GFICEAIEB@@CH
@>chr21:9902799-9902929-4
GAAGGTCCTCTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCTACC
+
FH@G?BEBHAF??ABFIA@@CCA?GEHBEGFGDHDE@HEG?@F@CGFFCBDIICDIEI8GDCCCCFEG?IHGCIAIEGDDIEDGHFFF?AAICFFIH@DG
@>chr21:9902799-9902929-5
GAAGGTCCTCTGCAGTATGNGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCTACC
+
GHCHC?C?BG??CBG?DHE&IHFAAACDHGEA?GEAIIHFD@ACCH?DBB#?EEA@FIECECHI@@ACEIFHEFA?EDCFCCHAH@"AE?ADBDAAGFEE
@>chr21:9902799-9902929-0
GCGGCGTACAGCCTCATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCAACCAGTGCAGNGGCTCCCCATTGTTGCCCCTGAGCTCCTGGGG
+
DIBHIF#ICICBF+CD?FFHB?F?H@H@FB@??AGBGGGDDHFEIH?@FAEAFBIGAICFHDEIB?I*EHH???E?EBCH@CFIFEI@GEFDABHFHI?D
@>chr21:9902799-9902929-1
GCGGCGTACAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAACGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCTGAGCTCCTGGGG
+
FA@@DEG@IEAF?EIECIFDC?CDDFB@HHIF@AEAGCHD?CFIDE%B?EACHIGHHBH@EEG?AGICCHHCBDHCEAGGDBFDE@?EGBED@AF,BA?B
@>chr21:9902799-9902929-2
GCGGCGTACAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGCGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCTGAGCTCCTGGGG
+
ICIBIGH#AIEHH@@CFDCFAICA?DHGHF?HFDAHCB@AG?BGFFGBCF@E?GI?BF@GECF@H@H?ADAIAFHIGIG?AAGIDGIICHGEIBFAGAF@
@>chr21:9902799-9902929-3
GCGGCGTACTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGATCCCCTGCACTGGTTGCCCCTACGC
+
D@IB?AD@FBCGEIEF?BDFCEEECCEDIAECDGDGBHIAG?CFFG@?IIGHCGGHCGI@GAEBIDEEACED@FG.B?BC?@AFHAHE?IGA@G@FH?BH
@>chr21:9902799-9902929-4
GCGGCGTACTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCTACAATGGGGATCCCCTGCACTGGTTGCCCCTACGC
+
I?FFEDHCHADDCIAH?DHD?FGGGFGC@HEE@DIIFBA?HE@FHIFAGFD?@H?GF??D@GCD&?@HDFBHIE?'@@DHD@?FAE?GFD?DBFCBGEHF
@>chr21:9902799-9902929-5
GCGGCGTACTGCAGTATGTGTGCATCCACCTGTCGTTCTCCACAAGCCCCAGGAGCTCAGGGGCGACAATGGGGAGCCCCTGCACTGGTTGCCCCTACGC
+
ADFGCHH@BEHFFF?DGIBDHAAHGIFE?H@BHH8EAHEHH@GCCFD@GAIFEGGCCADFA?FF;IDGAHHAH?EACHI?AGAH@ACGGCFCGF@GAHCF
@>chr21:9902799-9902929-0
TCAGACGGTAATCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGTGGCAGGGAAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCTGAGCTCCT
+
E@DI?DIHG?@CHF@F?IFA?EDEDH@EEHCGDBCEFFI@@?D@?ECF?CFBC=D?CCHCB?BDCBEDC?D@HB?FDCHF?HAEGGHDDIII@B??HEDF
@>chr21:9902799-9902929-1
TCAGACGGTATTCAGCCTCATCCCCAGGGGGAGACTGTGGCCCTGTGGCAGGGTAGGGGCAACCAGTGCAGGGGCTCCCCATNGTTGCCCCTGAGCTCCT
+
BCCEGICDGF%D@IEGA6FAAAAH?ED?G?@IEE@AGBBG.B@E@GECDC?HI@CFEEI?IHHBBF?CCIFGCCGEHA?AFH*ABFEAHE?GIFFB@B?F
@>chr21:9902799-9902929-2
TCAGACGGTAATCAGCCACATCCCCAGGGGGAGACTGTGGGCCTGNGGCAGGGTAGGGGCAACCAGTGCAGGGGCTCCCCATTGTTGCCCCTGAGCTCCT
+
EA?GII@ICE?IH@?I?DADCIAI@IBCHH@HF?FCFDFGEBDD@8C?EFBI@IFB@EIDE@2@BIDII?GBBEBBF@AFD@@HGCEGEIA@ABACHHEA
@>chr21:9902799-9902929-3
TCAGACGGTAATCTGCAGTATGTGTGCATCCACCTGTCTTTCTCCACAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCT
+
??ED?D?GGAECAGC@@IAI@I?IBABADIIDEI?BA@CC?I@D?AAHBIHBHADGCAGEEIDECECBGICBABDCDDAACDAG?IE@HHBDFHCICGBA
@>chr21:9902799-9902929-4
TCAGACGGTAATCTGCAGTATGTGTGCATCCACCTGTCTTTCTCCTCAAGCCCCAGGAGCTCAGGGGCAACAATGGGGAGCCCCTGCACTTGTTGCCCCT
+
IEBCBH?DG@I??G@H@DIDEEFFGEDCG?HBGBFEHAE@@D@7B#F@@IAF.?ECAAB?GBCHIEBBDE?G@A?IDA@GEEAGECIFDH-IF?FA?GAA
@>chr21:9902799-9902929-5
TCAGACGGTAATCTGCAGTATGTGTGCATCCAGCTGTCTTTCTCCACAAGCCCCAGGAGCTCATGGGCAACAATGGGGAGCCCCTGCACTGGTTGCCCCT
+
BAFBHDHGFDFC@EHFACBIGF?EHIGG@?@?3ICEGIDDBIDEEDACGGFF??DHABGHBDH=?H?AACB7DIIAHAHC?F?GA@FCGGGEGGF@EEAG
@>chr21:9902926-9902983-0
ACCACTATGTCAGCTCCCTGTACCTGTGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
@EEBFFDDAHAGGFEICBB?/@?@C?-CEDDEDI@HABFAHHHH?HEC@B??FHB@GEFFB?CGAHIAABBHDE@BDBA@@@AE@GI@BED@D@EGEB?B
@>chr21:9902926-9902983-1
ACCACTATGTCAGCTCCCTGGATCTGAGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCAGGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
D@EFIFGGI?DEHIEC?AFDAIGFHAGAEGAIFBDDGIGBCGHFAA?B?IAID?FDEEDBC8AIECF?HG@BBIHADAG@@A@DI@?GIE?A@GI??F@H
@>chr21:9902926-9902983-2
ACCACTATGTCAGCTCCCTGGATCTGGGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
@EB@ED@I@DICIHB?DHHCCCHE?A'CGAEICHFEIHDC?D@CCFB??EBDEEF@?BBIFBEABIHC?AAC?FFABAHEI?FAH?F@ACDCCB@??BDE
@>chr21:9902926-9902983-3
ACCACTANGTCTGCCATGGGTGCTCATTTCACAGGTAGGGAAACCAAGGCTCAGATCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
GHIFEA?%EC?DAIDC?FDH@ED>IDBF@AGFIDGD@CBEH@?DDADAB@EGIHGAFHIA?EB@ICG@GDFIH@HABDGFGAGHGHIGDBHDCDCIFBFD
@>chr21:9902926-9902983-4
ACCACTATGTTTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGGTCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
FCH@EDDAIF(FACGB@FIIGBFDCGBCDIBB@FG@GI@GBDHI@HD?DIBGAD?@CG@EBFDAIDCG@G@GFDC?G?E?EI?EEBGIEC?@BFDEAE@G
@>chr21:9902926-9902983-5
ACCACTATGTCTGCCACGGGTGCTCATTTCACAGGTAGGGAAACCAAGGCTCAGGTCNAGGGAGCTGAAATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
AIBAFE@HH?EHICDF4?I?CBA=@DHF?DC??AAEI@I@GAH?BC?BAEAFH?DE?)ICIICHE@HI+??HC?C@HGICF??ICFDIFADCC?EHDG?I
@>chr21:9902926-9902983-0
CTCAAACCACGCAGCTCCCTGGATCTGAGCCNTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCACAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
E@HA-?@H@EBCHIBFDDIEI@AFBAB?HII+CFF?H?C?D?EIAFGC?HADAAIFH?HEB@IE??G0I?E?E??A@@FAAHI@GG@@?I?DBDFFF@D@
@>chr21:9902926-9902983-1
CTCATACCACGCAGCTCCCTGGATCTGAGCTTTGGTTTCCCTACCTGTGAAATGGGCACCCAGGGCAGAGANCGGAAGAGCGAAAAAAAAAATAAAAAAA
+
ECAG?GFAIG@HDICF@ACI@BIDHG?DEI,ICCAE??BH@?BDD?ADGFH?@?EFB@I?AB:DHCHCA@B-H@IACIGD?BFIE?DIBDEE5CIHCIDC
@>chr21:9902926-9902983-2
CTCATACCACGCAGCTCCCTGGATCTGAGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
EDGHHAGDIBG@@?G?GICFGFCEAEHGGHCDBFIGGCI?EECEIGCIEBBHCDCEBFGDHCGIFDAHIDHHCGDBGII@F?HCAF@CBB?G@FEE?1AD
@>chr21:9902926-9902983-3
CTCATACGACGCTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGATCCAGGGAGCTGAGATCGGGAGAGCGAAAAAAAAAAAAAAAAAA
+
IEEBE@I<?BD@IHC?B?B?IAFDIIBEIDIDBF@FEF@@EGHF@GBCAF?CFIDFCDHBFA?GD?@@HDIDGDD4FCCHE@IC@B@ADDCAEFHDEIGB
@>chr21:9902926-9902983-4
CTCATACCACGCTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGATCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
DFDBF@BFBAHAA??BFHEDI@GAFEHA@GF@CBA@HIEDICGDHIH'HGBECBHB?HEHFEGFEBHCE@DGCGFGH@EFHDAIDG?IBBCHBGHAIFBB
@>chr21:9902926-9902983-5
CTNATACCACGCTGCCATGGATGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGATCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAA
+
F@'CGAIDCAD?FIIIGIDC:G@GD@IE?F?CGAABFBFEHFH??AGEAIIGGHH@B@DD?FEGABFIHECHHCA@CEH@A@CHFG@@FFDAEDDCEDCH
@>chr21:9902926-9902983-0
GAAGGTCCTCAGCTCCCTGGACCTGAGCCTTGTTTTCCCTANCTGTGAAAGGGGCACCCATGGCAGAGATCGGAAGCGCGAAAAAAAAAAAAAAAAAAAA
+
CII?IF@@AEFB?GCB@HBI@GFAC@HCHDFC8I?FCEAHF>D@?EHICG)@??AACE@G?IEHAI@FGFED?EHB3B@CAGG?GBF?IFEAAFFDHHGG
@>chr21:9902926-9902983-1
GAAGGTCCTCAGCTCCCTGGACCTGAGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
AHCHF@GI@GDECFGFHC@EC?EGFECB@EBBFDEB@ICD?HDFDDHEEECFG?FIIGH@BCGBGHBDACIC??CADDHH@HACDFGC?G?F?FF@C?DI
@>chr21:9902926-9902983-2
GAAGGTCCTCAGCTCCCTGGACCTGAGCCTTGGTTTNCCTACCTGTGAAATGGGCACCNATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAG
+
@B?C?GDCFFHG?FAABGCCH?@BAHIHFHBFAEA?'ICFHDDHE?AI@D@I@@IFA@"B@G@E@BFIAHIHEAEA@IDHABCAIADD@IAGHE?DI?I1
@>chr21:9902926-9902983-3
GAAGATCCTCTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGGTCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAANAA
+
CEB@:II??FHB?ICDBDDA?@HGH@?ACHGC?H8GA@B@EIEDD?GFHH@?BBFDHDCAFB@BA@GDB?IE???@BA@AIB?I@FCBE?G@?HE?B'?E
@>chr21:9902926-9902983-4
GAAGGTCCTCTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGGTCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
HAC?@HA@@ABIH?DCIBEABAIHG@G@?FGBACFB@B@BIH@H?GFIDBGCFDADE@DIE?BGIAAICHBCIDDIE@IAHHA@F@E?BFHCFD@CFHFC
@>chr21:9902926-9902983-5
GAAGGTCCTCTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGNCTCAGGTCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
FDIGE?CGDFHIIBBCI@FD?I@A@GDCCBH@C@CCFFDACF?AIBF-EGHD@@GEDBAC@CBEHACDHECHCD?FBDI@HA@FDEIEGIDHFDH@IDIA
@>chr21:9902926-9902983-0
GCGGCGTACAGTTCCCTGGACCTGAGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
@DBIGH?GEAC&HI?IEHHEHHDBEFA?IFDB?GFD@GIEAEICFE?ABIEGBG@DEB@@@IH@HF?AI@DFACIHBDH??@EDACGHDBDAAFHDH?HG
@>chr21:9902926-9902983-1
GCGGCGTACAGCTCCCTGGATCTGAGCCTTGGTTTCCCTACCTGTGAAGTGGGCACCCATGGCAGAGATCNGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
B@AECEDFH?GGDGDD@IAFB@?C??I?AGDICGF@@BGHHC?EFDFG7BAGEAA@A?DIFDAEC@A?BH5AEED@IDBICFBBABE?HDCCFIAIE?@D
@>chr21:9902926-9902983-2
GCGGCGTACAGCTCCCTGGATCTGAGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
CBCGIID?AD@DI@FH?@GBDABAD?FG?IIHBFBEEBB?I@@CEGEDGBBBHBFDE?BDE@?BE?GB?FEEFEACHBC@FG?F@HHCD?IFHIEFEHIC
@>chr21:9902926-9902983-3
GCGGCNTACTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGATCCAGGGAGCTGAGATCGGAAGAGCGAAAAATAAAAAAAAAAAAAAA
+
BDFFH8C@BHCHFDHECDG@IF@DGHII@HAFFFD?FAAGHIBED?ADDD@@HFAB@EDAAGH@C?CGGCGBFABAHACGCFEH<G?F@DB@ADFIEAFC
@>chr21:9902926-9902983-4
GCGGCGNACTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGGTCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
?DA@DB;?EEG?IGCCH?HF?IHHA@?CAEDHEB@BIIDHBECEBD?GHE@?H@GB?E??FBGHBH?@FAIF?FEBGCD@G@GECGDCIFBEDFHECEH?
@>chr21:9902926-9902983-5
GCGGCGTACTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGGTCCAGGGAGCTGGGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
CDCFBAA@EIFCHFGD@EBHCAACCB??GGEFCGEH@?BA??AIIAGCBEC@G?EEE@DGDGI?E&DIBD?FIACC@B@CEAGGIIC@CHFECGICGGE?
@>chr21:9902926-9902983-0
TCAGACGGTAATCAGCTCCCTGGATCNGAGCCTTGGTTTCCCTGCCTGTGAAATGGGCACCCATGGCAGAGATNGGAAGAGCGAAAAAAAAAAAAAAAAA
+
@IFAEHIGDEGCBIECFBCAGDD?AI-GFH??F?GGDI?H?D?9H@IGA@EAABAFG?EDBBHADHHGDA@@B0HBCD?ABF?DCEHFH@HIDBIHBDEE
@>chr21:9902926-9902983-1
TCAGACGGTAATCAGCTCCCTGGATCCGGGCCTTGGTCTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
E?GEHHAEB?@HBFDEFG@BFIHCD?)E=?@@AGDFC1BFCB?AEAGDGGA@?EAHIGH?@B?BFBDH@FIFG@GBHAGCCFIAEFIB@?EADHCGF@GI
@>chr21:9902926-9902983-2
TCAGACGGTAATCAGCTCCGTGGATCTGAGCCTTGGTTTCCCTACCTGTGAAATGGGCACCCATGGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
B?EGDBIEDBIEGFGDIHC.EFBC@FBGDEEFEHGCIBE?E?FHEEB@BCFFDEA?@GHFGID@@GCEE@@@E?BCIA@?AGDBCHIHHDFF?GHAHBAB
@>chr21:9902926-9902983-3
TCAGACGGTAATCTGCCATGGGTGCCCATTTCACAGGTAGGGAAACCAAGGCTCAGATCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
DA@EGEIFGEHDCDIFEBABIBDF?F@DHHD?CAB?IAID?A?DAC?@@FDCCGF?BFFIBDCIDFFECAEB@DI?DFDD@I@DFI@@AAEDHIEAEFB?
@>chr21:9902926-9902983-4
TCAGACGGTAATCTGCCATGGGTGCCCATTTCACAGGTAAGGAAACCAAGGCTCAGATCCAGGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAT
+
DEECI@@BAFBIADAEAIBHFHBABGGIICDHEIH?FHH0GDIF@GBGHDHD@?IG?CDB?G?D?FFGB??EID?GIHFFA@FIFDBAFEA@@?FHEED&
@>chr21:9902926-9902983-5
TCAGACGGTAATCTGCCATGGGTGCCCATTTCAGAGGTNGGAAAACCAAGGCTCAGATCCAGGGNGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAA
+
@BBHBCIAGDIB?H?@IC?EDDB?DIAIDAFDC>FICC#FF,HEB(DDCGDABBABFEGBE?BI1HHH@IDIBFAEBAIFBACG@HFE?HHBGBHF@H?C
@>chr21:9903283-9903428-0
ACCACTATGTCAGCTGGTGGGGCTGGTGGCTNAGCCACTGTGGCTCGGGGACCCCAGGCCATGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAGCA
+
F?@BFBG??EH??HHIIG?@AEHC?CDHIFG%EDGGBAFBC@@C@BC?GDF@CFEA@E?DF7?CH?AFDIFG?EA??EFFFFAFAACGCHBEHAHB@?GH
@>chr21:9903283-9903428-1
ACCACTATGTCAGCTGGTGGGGCTGGTAGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGNGGGCATGGAGAGCAGAGTGCGAGCA
+
?AH?GDC?AFFIDIBCDB?G?@HAAII)FBCHB@ABGDGBEFAHHCG?@?D@HFFFCHE@AIECGH?CEFCFHB=GDBAF>@@FGEFDI@??HH?@EIIE
@>chr21:9903283-9903428-2
ACCACTATGTCAGCTGGTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGGAGGGTGGGCAGGGAGAGCATAGTGCGAGCA
+
AHH?GEFDCCGGBBI@FD?@?@AADGI?EFDDAADFFBGHG@DB@H?HCAFCFEEBGIIA@CHDGFFAH"?H@DID?DFGDFDHGIBD@.?HH@GCECCD
@>chr21:9903283-9903428-3
ACCANTATGTCAGCCATGAGTGACCAGGGCTNTTTCTGTCCAGGAGACACCTGCCCTGCCCCATATACTCGCACTCTGCTCTCCCTGCCCACCCTACTCT
+
BEDG"AEDGH@GHBHBGI?@CHGI@GDCFI@5E@DHEHC?GIAGHBG@CBC?H2AIDGBD@ECBH@;IHDI?CGCAD@CEDHB@HI@@ADABBIHEAE@E
@>chr21:9903283-9903428-4
ACCACTATGTCAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACAACTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACTCT
+
@FCIHIBEDDBFDF@F?CAHD?AEBF?CAGFG?IEIG@BFGABE@@EH@GHIEBHDCBF?ADA?FGBEFDCFD@FBCDIBIE?ED?C?HGEB@ABAFCC?
@>chr21:9903283-9903428-5
ACCACTATGTCAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACAACTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACTCT
+
?EEGGIDEIIEHAHFCBIDBA?HA?GBIBBC<HIIE?@HCFADGIIHEEIGAGEFHHAGBG@?BCAECBAACBCDBGAFAB?GH@@DCHGGGBHHIBIAG
@>chr21:9903283-9903428-0
CTCATACCACGCAGCTGGTGGGGCTGGTGGCTGAGCCACNGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGCGCAGGGAGAGCAGAGTGCGCGC
+
G?EEIIEDBHEF@AIDFCECAABE@?D@@IEDBIHGFFC7H@DFBFBFB@FGIHFIDGECE#EAH@CAIG?BFAHEH&@6DCC?@DDGECD@EGCI@1?C
@>chr21:9903283-9903428-1
CTCATACCACGCAGCTGGTGGGGCTGGTGNCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAGC
+
IF?EIDE@CFE?A?IF@GAIFFHDD?B?H=CEI@BD??B?@DBCGEBHA@CAAIGE@D@A@EIDDAHHCGCEBCCIDDEDICA?@FFHDHHEGCABADAH
@>chr21:9903283-9903428-2
CTCATCCCACGCAGCTGGTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAGC
+
EFDEG2EEGBHEBFH?FF@DHDCBDEDCDCFIE?B?G?AIA@DCEDA?HFEDABGAIIDA@?FHHA@ECECIFHBIIBHA?EDIBIE@G@@H?BFCC?GE
@>chr21:9903283-9903428-3
CTCATACCACGCAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACACCTGTCCTGCCCCATATGCTCGCACTCTGCNCTCCCTGCCCACCCTACTC
+
FB?D?HEBAFDC?GHAGCFEBGBBC@@HIECGFCCCGIAIAHAIHBFIAGAH@HAFFIG@EBC@IB@DIEDBHBBBGDA?;?@CDF@EAGEBBEH??IDB
@>chr21:9903283-9903428-4
CTCATACCACGCAGCCATGAGTGACCAGGGCTCTTTGTGTCCAGGAGACACCTGTCCTGCCCCATATGCTCGCACTCTGCTCTCTCTGCCCACCCTACTC
+
FGGEDFFDCBEA@CCGEBHFGHBEA@EEAFCIDCB?"IIH?G@CHDG?E?G@FGIFECF@C?GEHHCFDFB@HFGHE@CCF@HG2CAIGHCB?GEI@DGC
@>chr21:9903283-9903428-5
CTCATACCACGCAGCCATGNGTGACCAGGGCTCTTTCTGTCCAGGAGACACCTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCNTACTC
+
IHEFDDI?DAB?HECBDAE#@HE@DHAFGC@ECH?GABHICFDHDDDI?GCCBIFBHEBHHGH@E?@BIBBIEED@DCDADFBHEBCHAGBHHC.@ICFD
@>chr21:9903283-9903428-0
GAAGGTCCTCAGCTGGTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAGCAT
+
@IF?CE@D??CBBED@IBCG@B?IGH@AABFBC?CGGFA?ADEIIDFACH?DDHAICACG?C?GGCABFBCHHCI?EHEDADFIAEI@??DH@EHEIAAF
@>chr21:9903283-9903428-1
GAAGGTCCTCAGCTGGTGGGGCGGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGCGTGGGCAGGGAGAGCAGAGTGCGATCAT
+
GBFC?FIIBEBBDBIE?B@AD@;FEAIHGFDA@AC@DAI@EI@CE?GCBD??D?@AFEBAD?BFC@GEEBE!AF@HFIIFEEEHDEE?AAE@@BI?-FGC
@>chr21:9903283-9903428-2
GAAGGTCCTCAGCTGGTGGGGCTGGTGACTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGTGAGCAGAGTGCGAGCAT
+
CDDHAGDCGAC@FIEGAEIAGAG@CBH3B?AH?CFE@BHAACAACAAAGGCHCIEA?@IIC@EI@AHCHAFEB?FCHABGBD$F@CCEICCICBA@HI@G
@>chr21:9903283-9903428-3
GAAGGTCCTCAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACAACTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACTCTG
+
HG?EG@DB@B@@@C@?IAGEBC@FBBF?DHHCBFG@CAGGDAD@FG@F@?GDGGCAE@HABHEEGIIHDHICDFDHHCGBG@D??DGFF@??CAEFEGEF
@>chr21:9903283-9903428-4
GAAGGTCCTCAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACAACTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACTCTG
+
AEIGA&@II@BDGIHGCDHIACAIHHBGC@HHCCECFDII?HIB@AI@CGBB?DFEEBHG@GAAIAADGHEGHGH?DFIBDFHDBB?CGEH?CCF?@A@G
@>chr21:9903283-9903428-5
GAAGTTCCTCAGCCATGAGTGACCAGGGCTCTTTCTGTTCAGGAGACAACTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTATTCTG
+
FD!B<GBECC?IGDD@BFCGIECIFHHEB@???AIDH@9D@@CIIEEEF?HGIH?HF@FAI@GCAI?DHAFBAAABICF#HEEFB@HGEHBDB@F2C?EE
@>chr21:9903283-9903428-0
GCGGCGTACAGCTGGTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGANAGCAGAGTGCGAGCATA
+
?@FFB?CIE?H@EFIDAAEF?A@CB??FIHDEEEHGCF?EBEFEBBECHEB?HAH@FAGF@??GG@?FCHCE@CBIHEADAD2II?BIG@B@IDBIEEID
@>chr21:9903283-9903428-1
GCGGCGTACAGCTGGGGGGGCTGGTGGCNGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAGCATA
+
@BCDABFAHAA>I?H0HDGCH@EHIIH@+ID@GDIHEBA@@CAFEEHE@CCACHFHIHEIGBEIAAEE?DDEFCAD?EDGACBCCCBED?HCFEH@A@CE
@>chr21:9903283-9903428-2
GCGGCGGACAGCTGGTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAGCATA
+
FFGGBH-FG?BG@?D@III@C?BAHAAGH@EFGDBDGC@FDCEDHFG?CHFAFAHAHCGADIDECGIGIAAFIEHDEIHGFDFIFE0AGIIE??FI@DAA
@>chr21:9903283-9903428-3
GCGGCGTACAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACACCTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACTCTGT
+
FFGEC?@DAFAEGHD@FB@AIEGDEGAB@CHAGF?CDBHGIC@@?@FAH@EEFBCABAEC?@HBEGBFIGFCACGAEG?GGAHCEI@CBDGGAABFAG?H
@>chr21:9903283-9903428-4
GCGGCGTACAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACAACTGTCCTGCCCTATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACTCTGT
+
BIIDCACCHAFA?CGDHIBBHEFI?HDBIBGACIGBABFGGI@DFBEH?0HACIFA?D?,FD@HI@CHIABDDDCH@GC?EIIDDIEABH?BFDIEA@DC
@>chr21:9903283-9903428-5
GCGGCGTACAGCCATGAGTGACCATGGCTCTTTCTGTCCAGGAGACAACTGTCCTGCCCCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACTCTGT
+
F?EB?CDF@EAFFACCDBHEH=AB)EEEF?D?@GCC@HID??FECBIHBEDH@EBDDHBCAGFCFCAIDE@EBIIFGABIFI?G?EFEGHCBHEHH?AFH
@>chr21:9903283-9903428-0
TCAGACGGTAATCAGCTGCTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGANCCCAGGCCAGGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAG
+
@EBE@BEFAHDE?IGECG)AIGFHEAHECDFIBGFGABBG@EGAECFDEB?B@6?GD?CGCBCCDEEBD?CHEBGB?IF@C?@ACDAFFEG@G@AG?HHI
@>chr21:9903283-9903428-1
TCAGACGGTAATCAGCTGGTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCCAGGACAGACTACGGTGGGCAGGGAGAGCAGAGTGCGAG
+
IHDCAH?EIBGDA@CH@H?FGC?F??@FIGBGGADGFIADC@DIFGG@GGDBH?EBEG@AFHI@CFFBGH+I?(FEBE@HGICHGGHBADHHECD@DDGF
@>chr21:9903283-9903428-2
TCAGACGGTAATCAGCTGCTGGGGCTGGTGGCTGAGCCACTGTGGCTCGGGGACCCCAGGCAAGGACAGAGTAGGGTGGGCAGGGAGAGCAGAGTGCGAG
+
CBF@BFHAEEHAABFHEC.DEFCBBACBHABGGFE@?DHIEEC?E@DCAHCEHHCHI@GGE7HE?CE?F@HDHDF?BIBI@C?GEDD?D@FC?AGBD@(C
@>chr21:9903283-9903428-3
TCAGACGGTAATCAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGACACCTGTCCTGCCNCATATGCTCGCACTCTGCTCTCCCTGCCCACCCTACT
+
A@EBADHD@EI??C?HEEGBAAHBAHIIGHIIDCCFFG@HGIC(DGADCCEBFDHHC@EE?D=A@@DFEFG?HC@GCBF?ECDBHCGHGCI?FEAABICC
@>chr21:9903283-9903428-4
TCAGACGGTAATCAGCCATGAGTGACCAGGGCTCTTTCTGTCCAGGAGTNAACTGTCCTGCCCCATATGCTCGTACTCTGCTCTCCCTGCCCACCCTACT
+
ADBGAAEDFB@A??@BDG?EAHDAHBFIIBFFBEG@HBEDEFCI?@AG>;IBIBBBDHDBIE@HFG@?B@HFB-HIH?I@FADIFHDIHI?EH@@BBEE?
@>chr21:9903283-9903428-5
TCAGACGGTAACCAGCCATGAGTGGCCAGGGCTCTTTCTGTCCAGGAGACAACTGTCCTGCCCCATATGCNCGCACTCTGCTCTCCCTGCCCACCCTACT
+
@@AGF@D?GA@#IG?IG?CDF@CD$@CBBHIID?AGHB@@GBGFAII?H@AFEF@DI?@???BF?@B?F@2BHHAECBEDH?DCEDAGFAEEFI@AA@DC
@>chr21:9903745-9903839-0
ACCACTATGTCAGCCAATGAGCCCCAGCCCAGTGGCCAGCCTGTGTGGGAGGGGAGTGGGGGTCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCACA
+
?AGFF?EBBGGIICBD4EGAH?HG?AECFADFFGEGCDHA@GHHFI?F@HCFI?@GG)IAGFCDD@DEFBF?@?ICII?BCADHCDA?DGHBEHDIDEG@
@>chr21:9903745-9903839-1
CCCACTATGTCAGCCAATGAGCCCCAGCCCAGTGGCCAGCCTGTATGGGAGGGGAGTGGGGGTCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCACA
+
9?GC@?C?AEDECGD?F@GH@FG?D@ADDD@@FDDCHH%HGGGI&BCCF?HFEGGAIAFBF@F?IEI?BE?EB??IC@HIFCBI?@?H?@CDI@H?@DFD
@>chr21:9903745-9903839-2
ACCACTATGTCAGCCAATGAGCCACAGCCCAGTGGCCTGCCTGTGTGGGAGGGGAGTGGGGGCCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCACA
+
GBAF@ADGADCHDGE@??@@@GB;ICBHCE???@CBD>AD@?BCGFEIDBB?@?D?CDHGCA2AAAD?CI?IAFHID@GGCGB@AHDACCGDAEBAIHBC
@>chr21:9903745-9903839-3
ACCACTATGTCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCACTCCTTCTGACCCCCACTCCCCTCCCACACAGTCTGGCCACTGGGCTGGGGCTCATTG
+
DBGBD@A@FB@@@HBHE@DC@?@@G?AD@IG@@BEFEB@HECABD?D%D5@AEIFCDB@ID?@GF?DIDCF?G?6HIF?CG?HCDE@DFEIFHEEABEDH
@>chr21:9903745-9903839-4
ACTACTATGTCTGCTGCGGAGCCTGCAGTATCAGAAGCCTCACACCTTCAGACCCCCACTCCCCTCCCACACAGNCTGGCCACTGGGCTGGGGCTCAATG
+
F?'ABA?G@DG6I?BI0AH?DH?IC@EI?C0?BHG@DAAF?AA-@I?FGAABGCFEAGH?ACDFCDHAGGIH??(GHC@?A@AB?BHHHID@FFIFH+BD
@>chr21:9903745-9903839-5
ACCACTATGTCTGCTGTGGAGCCTTCAGTAACAGAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCATTG
+
?CEEH@ECACACHFDED?@?CCDI7CH?AF?BI@EDFDCIGAAAIB?@B@I?BEICIC@?D??A?@AAI?FHCEDDDFBD?EEDFIA?F@FGCF@BGHGD
@>chr21:9903745-9903839-0
CTCATACCACGCAGCCAATGAGCCCCAGCCCAGTGGCCAGCGTGTGTGGGAGGGGAGTNGGGGTCTGAAGGAGTGAGGCTTCTGTTAATGCAGGCTCCAC
+
?FAACFFEFFD@IDBCABH@DAA??IABDFG@@BEAADHCD6GCDFBBGFBCABDHHE(A?E@EDFBBC@C@?AIEEHAD?@I@IFC5B@?D?HBGHFEF
@>chr21:9903745-9903839-1
CTCATACCACGCAGCCAATGAGCCCCAGCCCAGTGGCCAGCCTGTGTGGGAGAGGAGTGGGGGTCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCAC
+
CAHCGBDHD8BG??DECBAFBIIFG??DGEDAGEEBID?BAIAD@GDH?EHF'HGGHFG?AHFGH?EH@CHFICDGGDEICIBBI@DIIDAE@AHA@BFH
@>chr21:9903745-9903839-2
CTCATACCACGCAGCCAATGAGCCCCAGCCCAGTGGCCAGCCTGTTTGGGAGGGGAGTGAGGGTTTGAAGGAGTGAGGCTTCTGTTACTGCANGCACCAC
+
@AAGBABB@IEIAG?DDBIHADAGIGFDB?IBFBBA?DDD?GE?A*GBH?DAA@GHADC2CI@?=B@HBDBHAFDDA@B@EGCCB?GII@AF4HG,C?BC
@>chr21:9903745-9903839-3
CTCATACCACGCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGNTGGCCACTGGGCTGGGGCTCATT
+
IC@GDFE?C@A@GEBHGG?EBGECDCH?A@AC@AGHCCFCBIGIDF?EDFE@CFC??I@BB?DEFH?H%EEF??FC;E@IGHB@C?FA?H?HBDIDCBFF
@>chr21:9903745-9903839-4
CTCGTACCACGCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCATTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCATT
+
HHC<CDDEFAFIHEBDEHDDG@I??GBEHGEDBHIGGGD@@GB>GG?AHGBBH?I@ADF@BCBFBCHFBA@CGFI?CBIHBG?HHIHE@HGE@GED?ICG
@>chr21:9903745-9903839-5
CTCATTCCACGCTGCTGTGGAGCCTGCNGTAACAGAAGCGTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCAGGCCACTGGGCTGGGGCTCATT
+
HGBFI*HEHD?HCCHEFI?HDDHGDBD;?E@HCEC?EFD!*IAC@DEAEIE?C@BEGFCEI@BEBEIACEGHG?ABB4AHA?I?BECDB@?AC@GHBAH@
@>chr21:9903745-9903839-0
GAAGGTCCTCAGCCAATGAGCCCCAGCCCAGTGGCCAGCCTGTGTGGGAGGGGAGTGGGGGTCTGAAGGAGTGAGGCTTGTGTTACTGCAGGCTCCACAG
+
G?BCH?@E?A?GIGE?AFH@?HCECGEBAI@HBGGFECFBECIEI@EHCGEI?A@@BAGAAFHDHDDBICAACBHCHBB3EAI??B@DBIGBE@HFGDHC
@>chr21:9903745-9903839-1
GAAGGTCCTCAGCCAATGAGCCCCAGCCCAGTGGCCGGCCTGTGTGGGAGGGGAGTGGGGGTCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCACAG
+
HGAFIC?ECGADE?F@BCBC?GID@GEHBF@IGCHI5CGDI?C@ADCACGBFEGB?HHCHAB?D?DICHGGCIIICDHGBHFCAA@BGF@BABB@?BFGI
@>chr21:9903745-9903839-2
GAAGGTCCTCAGCCAATGAGCACCAGCCCAGTGGCCAGCCTGTGTNGGAGGGGAGTGGGGGTCTGATGGAGTGAGGCTTCGGTTACTGCAGGGTCCACAG
+
D@AI@EI@?BHEE"D?@FCG?7EFABIIE@CEBBGB?GA?@EBCE&CFHABFHDFHDCHH?EGFGG4B?GICHB?BBCC@-?FEAAE@GDF?%BEBBCCA
@>chr21:9903745-9903839-3
GNAGGTCCTCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCACTCCTTTAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCNGGGGCTCATTGG
+
&.E@HF?HFDA@CDGEI@G@DEHA?C@?BCHGIIECGDICIICG@BF2DH?@ABBEF?HD@?AFFC?HGGFIGDC?FG@DDAGEAD?.D?IDD?IFH?@@
@>chr21:9903745-9903839-4
GAAGGTCCTCTGCTGTGCAGCCTGCAGTAACATAAGCCTCACCCCTTCAGACGCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCATTGG
+
FCGDC?@HAB??CEFIE+EDGF@IGIHID?AB=BFICGA@G?:GAGD?GH?D#@GDHB??HDBFGA?@BDD?HEADI?EBH@@BACEGFGFHEFFA@B?A
@>chr21:9903745-9903839-5
GAAGGTCCTCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCATTGG
+
GGGF@DGGICDA@G?IAH?DC?DDHGHA?@IFIFDDDIGDB@DBBFHEBCFACDAEBIGE@FGEB?BAI@EBIB@HDGGBCBI?G??@DBGICD?CDA?A
@>chr21:9903745-9903839-0
GCGTCGTACAGCCAATGAGCCCCAGCCCAGTGGCCAGCCTGTGTGGGAGGGGAGTGGGGGTCTTAAGGAGTGAGACTTCTGTTACTGCAGGCTCCACAGC
+
IHF,HFGFGFEHC?HAHCIF@IDICDB@HFIGI@?HAEDICB?EG@GF?DE@BGHAHDBBIFE;AGCCE?HDGC!EEGAAIGB?EI?H@FFAEI?DDCAG
@>chr21:9903745-9903839-1
GCGGAGTACAGCCAATGAGCCCCAGCCCAGTGGCCAGCCTGTGTGGGAGGGGAGTGGGGGTCTGAAAGAGTGAGGCTTCTGTTACTGCAGGCTCCACAGC
+
CBBA;@B?FI@HE@FF@@?C?F@I@?IDGCF?@DFI?DEI@B@AE@DIEEFAADCFEAI@?HHBAB6I@@HBD@BCICGAFH?HBE@@GAAEEI@?AICF
@>chr21:9903745-9903839-2
GCGGCGTACAGCCAATGAGCCCCAGCCGAGTGGCCAGCCTGTGTGGGAGGGGAGTGGGGGTCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCACAGC
+
BDBG@EFAABEHDHFA@IHAF@BHAED8BED?DBCDIG@?A?BE?@CAFB?EFEBBIBGAAHEFH?IFEGIDB@@GHCDADIBBH@FG?AGDFF??DG@D
@>chr21:9903745-9903839-3
GCGGCGTACTGCTGTGGAGCCTGCAGTAACAAAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCATTGGC
+
@G@CFEFBBBICHAAIHCHCIFA@@@CBGB@6@DI@D@C?GGHCG?BAHA@CFGACHCBC@DIH@BFDECI?C?HIFGICDIHC?BDBGIHDFAAGE?BG
@>chr21:9903745-9903839-4
GCGGCGTACTGCTGTGGAGCCTGCACTAACAGAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCATTGGC
+
H@GBGGG@FB@HFEEGEEBCFGIHD6CFGD@D?AEH?EECCEDDGA?GBEFICDE@@H?GCDFGGDID@CDCAGBC?BHAICDHI@FBFDHDE@@G@HHB
@>chr21:9903745-9903839-5
GCGGCGTACTGCTGTGGAGCCTGCAGTAACAGCAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCATTGGC
+
HGHABFGIAHD@CCAHGFHIFBFHGAA@IFA@-BCEGEEHD?DFBIA@H@ECH@HEG@@H@CHFDH?@@?HBIIHIED?@CBBBHI?C?AIBFDDDIBDH
@>chr21:9903745-9903839-0
TCAGACGGTAATCAGCCAATGAGTCCCAGCCCAGTGGCCAGCCTGTGTGGGAGGGGAGTGGGGGTCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCA
+
?FIFFGB@IAGEBFDIE?DIFC?)BAFCDHF@IDHH??FA?DGD@GAFHCAI?AEGCFDD?IBCDEE@DIGB?F@HGDGBDCDCDAAH?GC@CCFEHFIB
@>chr21:9903745-9903839-1
TCAGACGGTAATCAGCCCNTGAGCCCCAGCCCAGTGGCCAGCCTGTGTGGGAGGGGAGTGGGGGTCTGAAGGAGTGAGGTTTCTGTTACTGCAGGCTCCA
+
?GBEDD?GIBIED@?AHH-F?D?G@?@GIDCCFB@DBCHDEIABABFDCDIEGEDIFCGGADCD@FIEEEBE@CF@I@C4A?FA?ADH@G?@FHD?G?F@
@>chr21:9903745-9903839-2
TAAGACGGTAATCAGCCCATGAGCCCCAGCCCAGTGGCCAGCCTGTGTGGGAGGGAAGTGGGGGTCTGAAGGAGTGAGGCTTCTGTTACTGCAGGCTCCA
+
D*G@HGD@DBH?GHG?@H@BB?@I?HCHAIHIHA@EEE@DHC?GI@EFCDA@AFH'HE@DH@@ECFHEAGFEFF@DCF?FEIEB???CBCC?G?H@@IIC
@>chr21:9903745-9903839-3
TCAGACGGTAATCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCAT
+
CI?CEAAGA?AFAHHD@DHGBIBBH?F?GGAIADHICG@HDD@CHABIABAGEBHGEC@?@IHFF?FF@B?DDDC?AGH?A@A@?@IHHCB?CB@GCEHF
@>chr21:9903745-9903839-4
TCAGACGGTAATCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGGCACTGGGCTGGGGCNCAT
+
ABDF??D?@BAC?@@GAH@B@FGCCI?HDDHABDEBIHB@AHEA?HI@I@DEDBAADAIEFGBGIHFEAAABDI@?GCHIF1FDI?CFF?HH??AC4HCG
@>chr21:9903745-9903839-5
TCAGACGGTAATCTGCTGTGGAGCCTGCAGTAACAGAAGCCTCACTCCTTCAGACCCCCACTCCCCTCCCACACAGGCTGGCCACTGGGCTGGGGCTCAT
+
GB?IDHDBDDG@AA?IAEGAF@HED@HFFGBBF@?FIBDGE?AC@IH@?FABACBCGEAF?IGADGG?ECFHEHIDHFCFBAHGIHEBGBFIIAD@CGDG
@>chr21:9903836-9904018-0
ACCACTATGTCAGCCCCCCAGGGTTGCCCGTTTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATTTAATGCCTGT
+
HD@?F.BIFB@B?CFC?CIDGECB9EFIBEF/AHCG@EFIBBAHGGGGI@FDEBGCHACD)EBBDHII@HFDIFICIHF?FHFABBIEAGAHDH?IBCBI
@>chr21:9903836-9904018-1
ACCACTATGTCAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGNCGCCGACCTTGAGCCATGCATTTAATGCCTGT
+
G@DBB@BA?GCE@C??AHDCHGA?CBAIAAHDGFGHCE?EBFBIAEC@C@GB@?AIHGFHHGEBAIC%HDCGHHEBHCDIGFCGDFE?IHBF?@DCBB@I
@>chr21:9903836-9904018-2
ACCACTATGTCAGCCCCCCAGGGTGGCCCGTGTGGGCTGGNCAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATNTAATGCCTGT
+
CADDAHCAHHIFBAADDE?G@HFEGD@IGDHDFABGIHDE)GDGDCBDHAFCI?CAEHHFHE@?@@EADDCFGIFHCFFGDBBDHIB@A.GCH?EEEHBH
@>chr21:9903836-9904018-3
ACCACTATGTCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCACGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCACTC
+
C@?A@@@DDFB@ABGGFICBACHCECFGFBDAI@IIDDHDAHFB@D@AGI@?I*A?DACGF?IDFEA?CEIGBB@G?BCIIGCFAHGDFEBIHFDHGFEA
@>chr21:9903836-9904018-4
ACCACTATGTCTGCCCCCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCGCCTAGAGATCACTC
+
CHEIHADHFCBBH?@G'A@DE?G@C?GDGDEB?AEIFHEG?EDFAGAEIGAHAIHEBF@G?@@GACFCI@HBE@FHHAI??BBID.E@DCAAECD?@IDA
@>chr21:9903836-9904018-5
ACCACTATGTCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTGAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCACTC
+
@EEFDIEFGEDD?GFH@FC@?IF?IDDF@GEFBAGABHFD@ED?CEA@I@E:@EGDGFIB?FDDBCECE@?ECGD@I@GH@FFE@CBGHHGGACFFHFFG
@>chr21:9903836-9904018-0
CTCATACCACGCAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATTTAATGCCTG
+
@HAIDAEIF?HHACHF@F@DE?DGCBF?FCCCBD@CBA?HIGB@IBEIECGGGDFFDHIGBGCCC?I?AICACDDCGGA?FGEE?@EHIB@FGDDHEGCD
@>chr21:9903836-9904018-1
CTCATACCACGCAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCCGGCGCCGACCTTGAGCCATGCATCTAATGCCTG
+
BGGGDF@EEGFFEFDEE@IBHHGD?AHICH@ECCAHBIIDCFGFCBD?@FBD@B@AEH?@EIAGBF7FHEAADEAAFE@C@CBG@@F??CGDF@?CHFBA
@>chr21:9903836-9904018-2
CTCATACCACGCAGCCCCCCAGGTTGGCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATCCAATGCCTG
+
FAHGHG?FBGEBEBFF6BAA?GH9CB?A??ECD@HDFEAGEBBGGE?BGCGGEG@GCDA?ADHGAGG@CDC?FHCDB@?@CIAHBCH?C?F5DDFBAA@D
@>chr21:9903836-9904018-3
CTCATACCACGCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCACT
+
BAEGH?@IHADH?IE?FC?H3DFBFGHDEBIDHIE?@CIBDI?@IGDE?EEEEDCFBBBGAABGFGDADBFDFHFCIAGIIECI@FBEIIDIFG2D?@EH
@>chr21:9903836-9904018-4
CTCATACCACGCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCACT
+
?AH?FA?I@C@CBGE@BABCHHE@GF@E@CHG@EAFEBDBGH?GEHG@H?CCDD@GAEHB?CI@EDGCIAFGEIBAHEDBIBDB@@BBGBGGCIDGEAGG
@>chr21:9903836-9904018-5
CTCAGACCACGCTNCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTCTGCAGTGGCTCCTAGAGATCACT
+
CIHC$GC?HG@II!CF@EEHB?BDEEHGH@E?AB@G?BCEE@DF?GHC@??FCFDAEEIHEDFA@@AA@HD?CA@C,CGHACEGCHIFDEIFHGAGE@EE
@>chr21:9903836-9904018-0
GAAGGTCCTCAGCCCCCCAGGGTGGCCCGTGTGGGCNGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGACATGCATTTAATGCCTGTG
+
@HGBFIB?CB@ACFH??BDEH?ICH@@F?HGEFDHC:@G$IIHCBFIHHABA@IFIEAFEFBG?IGDEHHE@HFFGDGGH2?DDB@FE@EBFIE?H@@IH
@>chr21:9903836-9904018-1
GAAGGTCCNCAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGGCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATCTAATGCCTGTG
+
HECACA@A>BHFGCHFG?@GFAAGDAEFHDA@@ECB@CGDFGFFH@'CEADEC@HDAFFI@BE@?GF@?IFGDEC@BEEGHHD?FFGF@FIAC@G?BCHB
@>chr21:9903836-9904018-2
GAAGGTCCTCAGCCCCCCAGGGTGGCAAGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATCTAACGCCTGTG
+
D?HIDICGHF@.@@G@IBAI?GCDEA)$CFHG?E@B?GHIIIBFA@?E@ACDD?AG?ACDDFHI?DHD@DEEG?DFA@AAGDCA@ID?CIHF:@@BGFIG
@>chr21:9903836-9904018-3
GAAGGTCCTCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTTCCATGTCAGGGTTCCCTCATCTGTCCCCTTGTGCAGTGGATCCTAGAGATCACTCT
+
GE?GGADDHB?H?@E?DHHAB??BHGEBEE@C?@GHGBBHGFG9DIF?AHHA?CCIGHBBBDC@IIE.I?HFE@@@?FECI?H:FBI?CDF@EIDAFCDF
@>chr21:9903836-9904018-4
GAAGGTCCTCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCACTCT
+
@B@?IE@?CHEHCE@EHFCHIAE?AI@IFHFAICAEFBA@AFIGICCB@AGAEIGF@IAAA?CIDD?AG?@GCAEFBBBBDEAHIA?GGI?CHAAIIG?E
@>chr21:9903836-9904018-5
GAAGGTCCTCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTTCCCCCTTNTGCAGTGNCTCCTANAGATCACACT
+
CG?B@IBF?HF@DIEAIBF@HFEGIFCB@?BBCADGGGGDCFDI?GCAGDDAEA@ECII?AEDF?A(FDFCFG?;HBI?@GG%IIHAEF!?BFHHFF&G?
@>chr21:9903836-9904018-0
GCGGCGTACAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATTTAATGCCTGTGA
+
DF@CBBHCCGCEEGH@H@?AB?IAIHAEI?BDC@?FIF@FCFIACFD?CDCDIA@?GHEGHFH?@FA@IFFDDFGEFEB@BFFAECEEG?GHFGHBFHH@
@>chr21:9903836-9904018-1
GCGGCGTACAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATTTAATGCCTGTGA
+
IBFCGHHF?DHI?FEHCIFCCBC@CEE@FDB?DFHAFBCDFB@FGIIC@GA?FAABFCBIIFCDG?@EBDACIIBG?EFGDEB@FBCCBDCICDA@DG??
@>chr21:9903836-9904018-2
GCGGCGTACAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGTCACTGGACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATTTAATGCCTGGGA
+
EHEHHDG.AGAAGDEDBHHA?HICG@BBFC?EIHG?IAFIA?IDA?BCE?E41@DAFIH@?CI?IF@B@FHDDAF@EH?GEFEDC?HB@BF@?ECFF(HC
@>chr21:9903836-9904018-3
GCGGCGCACTGCTCGCTCCGTGTTGGGGTCCCCCTCGGCTGTCCCATGTCAGCGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCACTCTC
+
BHCIAG-@IDGA2@E?I@AA?IECECFDII#EDBIEF@EGI@C@GEEAGABF.CCHD??DEHI?DEEAC@?GGHDEFAIBE?HC?DH@CBDHCFABB@CG
@>chr21:9903836-9904018-4
GCGGCGTACTGCCCCCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCACTCTC
+
IAFABIC@BEFB@F'?ECAEGHGD"CD?@DBBIECAEI?DEECBIBAHGIH?GBD@GAC@HABDEHGDC@IDHBF@HACFCDIAF@BCHEH@ED?F@EGH
@>chr21:9903836-9904018-5
GCGGCGTACTGCCCGCTCCGTGCTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTTCAGTGGCTCCTAGAGANCAATCTC
+
G@DCAIIFG@IEA?D@DAHB@@7EAHCIBFHD?EBCGDAICGGF@DEBAHA@DHEAIFHHAEG@GG@IGFCD??@$CDDFDHAB?IBDIH@G<@G#HBHD
@>chr21:9903836-9904018-0
TCAGACGGTAATCAGCCCCCCAGGGTGCCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATTTAATGCCT
+
HBC@CF?IC@CCIBCF?GE@IBH@GEH!GBCHCCEH@IBFDAEFII?GECHH@DBDEEBDE?IAHA@A?BB?HIDEBBEFFBCDA?CDDIHGIBBFIBBC
@>chr21:9903836-9904018-1
TCAGACGGTAATCAGCTCCCCAGGGTGNCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATCTAATGCCT
+
ECBCG?AAGBFEAABH6EEHEBIEGCB:IE@G@FEDGAAHICHFIFECCH?ICFHDICCDHFCAFIAHHI?AIEBEACCHCD?BBAII@FABEBDGGGBA
@>chr21:9903836-9904018-2
TCAGACGGTAATCAGCCCCCCAGGGTGGCCCGTGTGGGCTGGACAGCGGTCACTGCACCAGGGGCTCTGGCGCCGACCTTGAGCCATGCATCTAATGCCT
+
II?DD@IEBGE@@DFFCI?DGEGB@AG?CBDIFGGBFBIABGDAI@?CFDD@@?EGHEF@FCE?E?FEHGB@HAGHADBGH@?GF@BAFHI?GBCHA?DH
@>chr21:9903836-9904018-3
TCAGACGGTAATCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCAC
+
FA?CCG@CD??CDADFBGH??HF?@I@??HA@IHEEGIGBEIECEB@@HEFGBECHDE?@D@E@DFDICC?ADBAGGHDCCB?IEIABAGFD@BDBBCB@
@>chr21:9903836-9904018-4
TCAGACGGTAATCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTCATCTGCCCCCTTGTGCAGTGGCTCCTAGAAATCAC
+
B?ICADFIC?AGCA?FFEFH@DEHDB?DGHCEGCHDHEGAFIB??@FFEHHBB@EHCAEGEHHHDH?B??BDDCCAEA?@$IBBHGHCAGDCDD-?A@CB
@>chr21:9903836-9904018-5
TCAGACAGTAATCTGCCCGCTCCGTGTTGGGGTCGCCCTCGGCTGTCCCATGTCAGGGTTCCCTNATCTGCCCCCTTGTGCAGTGGCTCCTAGAGATCAC
+
FDBHH@"G@IFFGFBGGDHIAFFCFG@ABECGAA@AIB@ACG?FGGFEFBCAFAD@DAIB?@@?4CDDHD@?GHHIHIGHEF%CBGHECIIEIB@I@@CE
@>chr21:9904015-9904127-0
ACCACTATGTCAGCTGTTTCCAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTCTGACTCNAGGGTGTGGGCTCACTGAGGGACAGGACAGGCTG
+
@H?CCIHGIG?A?CDID"@H@IDC?EI?CAGEHAGHABA?BC??CG?@AABAFF?@HCAIEHIDA$IEGBEFGCI@CH@HHCCHBDGAE@I?IHAIHFDA
@>chr21:9904015-9904127-1
ACCACTATGTCAGCAGTGTCCAGGCTCCACTGGATTCCGCAGAGGACAGAACACAGCTCTGACTCCAGGGTGNGGGCTCACTGAGGGACAGGACAGGCTG
+
HGAB?CHFBF?AII2D@@EA??BHBFAEC???EEGB@FGCFECB@FAHCEG?ADIIDIIIDFC?HH@BFE@F6HFF@CFC@ICGBCHEHDG@G@IIDDFD
@>chr21:9904015-9904127-2
ACCACTATGTCAGCTGTGTCCAGGCTCCACTGGATTCCGCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCCCACTGAGGGACAGGACAGGCTG
+
GBGFCIDFFIECHIDCH?CH@@EGIBHGCBFCE?GDECAH@?BIFIAB??DHF@??DFDDAAAFICE@@HCBFICGF.IBF@BGFH@IDGEFF@CDEFBD
@>chr21:9904015-9904127-3
ACCACTATGTTAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCATCTGCGGAATC
+
EHDCI@CHAH3BIIB@I@ACCHFCG?@ICDB?AI@IE??FHIDIE?IIG??IIF?B?DGAGFG?EBFF@BBII?H?G@GCD??@EHAC'?F@CADFA@FI
@>chr21:9904015-9904127-4
ACCATTATGTCAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCATAGCTGTGTTCTGTCCTCTGAGGAATC
+
CGFB$BAEDEIECFCHE@DIEACABFEGC@?AEE?EHEFGAGHGEEFGGEDACCFI@HDGEEFCGIFBEAH?G,B?HH?HC@@DFIAIDBAGEIGGCI@G
@>chr21:9904015-9904127-5
ACCACTATGTCCGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGAGGAATC
+
BEHF@CIFIDI=CGGIEAIDDICGAIBBCDIH@@IFAIAGBIHGGF?GE?H@B?BEAIEBBHGGEGFC@?DAE?IHE?IEI@BHBHG@BCGGCIDBCD?A
@>chr21:9904015-9904127-0
CTCATACCACGCAGCTGTGTCCAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTCTNACTCCAGGGTGTGGGCTCACTGAGGGACAGGACAGGCT
+
EB?@BIEDEIFDADIH?AAEFCIAB?GFEGHGI@ACE???AAHIFDIICCFGIABEI@E@I7?HDBHDF?CHDIFFCIDFDEII@HHCHGBBDD@ADAEA
@>chr21:9904015-9904127-1
CTCATACCACGCAGCTGTGTCGAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCTCACTGAGGGACAGGACAGGCT
+
CBGD@AEADGDCDE?BHCHHI1?@?GB?GFFF@?E?E?IC@HIFCEA@?AAFEAH?GDHDA@FAHHIECDB?EEGBHCF?GEFIECGE@CBFCDFI?EGD
@>chr21:9904015-9904127-2
CTCATACCACGCAGCTGTGTCCAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCTCACTGAGGGACAGGACAGGCT
+
G@DBGCG@H@?CEAGFHHGCBDH?BFG?ICIIEGFBD@GI@AH?DDHEA@DH@H??DAFBCFHGHH@IAGIFID@BH@A@DC?FG?BAGGGIC?CIBB@B
@>chr21:9904015-9904127-3
CTCATACCACGCAGCATGGCCCTCTCCCAACCGCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGAGGAAT
+
CIIIG@CA@DFDIIBEBDDFDI?D?EAIIB?F-A?AIB?DB@AACHAGIGH@E@B@CAIG@EHEFB?GBICDAFF?IIB@DFIDF?HHCIAFEIHBBHEG
@>chr21:9904015-9904127-4
CTCATACCACGCAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGCCCCTCAGTGGGCCCACACCCCGGAGTCAGAGCTGTGTTCTGTCCTCTGAGGAAT
+
C@DAFEFGAFHBC@GD@@?@I?HHCCDFCIGBA@?E@EHEA?I?C/GB.FE?AAD-BACGDDBD?C!CFCEDFHED?C?HAB@ACE?CH?FB?F@IAGEH
@>chr21:9904015-9904127-5
CTCATACCACGCAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGAGGAAT
+
CFDE@EG?GGAIDAH?CG@DA?GC@G@?GBEI@D?HGAHECHI@AFH@BDCD?@IBCBA@ECICEB@EEECAH@@?AHFH@AAF?A@DBIDIEBBIFI?H
@>chr21:9904015-9904127-0
GAAGGTCCTCAGCTGTGTCCAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCTCACTGAGGGACCGGACAGGCTGG
+
FBHAB?IDEH@DFEE@EDCAECEIDDEFCB?HDGHEIE?C?ECHADFBHEBB9FDEFEAFHIEIFHICCCBC?EBA?IEGHFEF@HCF1EIFEE?IH@IH
@>chr21:9904015-9904127-1
GAAGGTCCTCAGCTGTGTCCAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTATGACTCCAGGGTGTGGGCTCACTGAGGGACAGGACAGGCTGG
+
FCEC@A?GCFI@?GHCHEH?EE?A?CDC@ICB4IIDAAICIGGFF?AFDHEE@BFGI0@II?FD?D?AFFIBF??IAHBFA?BHF<DICIEDDGF?FECD
@>chr21:9904015-9904127-2
GAAGGTCCTCAGCTGTGTCCAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCTCACTGNGGGATAGGACAGGCTGG
+
FCAF?C@IG?I?FACAE@AFII@CBCDBA@GEGAHD?CFCEFEG@@BACBGFAHFDCECCHF@GEEBAHAGB?@A?CFCFEG'HA?A)DIEB?HEADA@I
@>chr21:9904015-9904127-3
GAAGGTCCTCAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGAGGAATCC
+
BEBBBDH@IEC?@AAFFF@AIDFCEDF@IC?FI@BICDDHACCCADEEFAIF$C@AHH?HE?@GEEIIHHAADIBDCIEC@HIHBBAIEF?A@?ACDHHF
@>chr21:9904015-9904127-4
GAAGGTCCTCAGCATTGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCTCACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGAGGAATCC
+
C?IFFCBFIEI?DI?"CD@AFAG@DH@?DHCB@?E?AF@GCBI@I??IIHE?EEDBD?<F?FI@?G@GEHG@H@@?GEDGAGAFA?IFHEFBGHI?D?EH
@>chr21:9904015-9904127-5
GAAGGTCCTCAGCATGGCCCTCTCCCCACCCCAGCCTGGCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCAGTCCTCTGAGGAATCC
+
?AI@AEGEDF@HEEFGH@@AABDB?H*IHDEFHCIG?E8AGBECEH@@G?IHFDD?@D?CDGHIGCDAHFI@BB@@?DEADBI'FHBCH@CGHCAFEHGD
@>chr21:9904015-9904127-0
GCGGCGTACAGCTGTGTCCAGGCTCCACTGNATTCCGCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCTCACTGAGGGACAGGACAGGCTGGG
+
FEAHCIBFIEFA?FGAAE@CAGGDICFC?C0??CGH@CEDFG@C?EFIHBDGC?F?HHGGDCFB@FCIFAFDFAFFIBAIDIAC@@FDE@FFBAIGB??I
@>chr21:9904015-9904127-1
GCGGCGTACAGCTGTGTCCAGGCTCCACTGGATTCCGCAGAGGACAGAACACAGCTCTAACTCCAGGGTGTTGGCTCACTGAGGGACAGGACAGGCTGGG
+
F@CDBD?F?IECEGIBHG@CEDBBD@GBAFIEABIHE@?AEI?@?CCHBGEFGG@AAF8?IBI?IDHAHIB+ACBGGDIABBGIIAGE@DGI?BGEFDDC
@>chr21:9904015-9904127-2
CCGGCGTGCAGCTGTGTCNAGGCTCCACTGGATTCCGCAGAGGACAGAACACAGCTCTGACTCCAGGGTGCGGGCTCACTGAGGGACAGGACAGGCTGGG
+
*@F@FF@,CCBFCFH@E@5A?A@CCCI?BGBCD@?IFAH@AIAFEHGDIAA?CEFGDDDBFBC?GGEAIF+?@CI@GFBCFGI?DEFBBFDGHFHFBFCC
@>chr21:9904015-9904127-3
GCGGCGTACAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGCGGAATCCA
+
DDDEFCEHHAEFCGBHG@H@F?BHGIFHDDFEIHEEFAAHF?DEICHADA?@FI?@IBBDGHGGCCF?AB?@??BIADEFHBF@BAIB?HHAHDBDHCB?
@>chr21:9904015-9904127-4
GCGGCGTACAGCANGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCGGTCCTCTGCGGAATCCA
+
DFD?@DEG?D@FF,DEAGDF@GCBGBFFFCEED?AGBAB?@?@E@B?GGHI@?GBA?CEIH?CBD?B@HICIGB@@@HFBAA*AGDHIEDEEBCDEH@@C
@>chr21:9904015-9904127-5
GCGGCGTACAGCATGGCCCTCTCCCAACCCCAGCGTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGCNGAATCCA
+
AIHBCAIACFCFHBGEHCIB@DDIBDECDH?DAE#FAFCI@EBCGHACCAFAFEGGBHFBE@?G@BCBECEDDF@GFDDIB?DAGF?ICECB#BBB@@?G
@>chr21:9904015-9904127-0
TCAGACGGTAATCAGCTGTGTCCAGGCTCCACTGGATTCCGCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGACTCACTGAGGGACAGGAAAGGC
+
@HGAC@?BIH@DHC?AIDFECC@?@BIIEGBD@EG?F@AFIB@DD+HGABFFBCECAGA@CI?D?FA?IGBCIGBCE#D??FCBABBF@EECIAE8H@BE
@>chr21:9904015-9904127-1
TCAGACGGTAATCAGCTGTGTCCAGGCTCCACTGGATTCCGCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCTCACTGAGGGACAGGACAGGC
+
FEGIBECDCBAAG??AGHIGCEBCH?IGHCDGDBGID?GHFD@FH@AAFH@ID@DB@@E@A?FBCHIGAGBECEIIC@EF@FADBCIHGHAGADA?IF?@
@>chr21:9904015-9904127-2
TCAGACGGTAATCAGCTGTGTCCAGGCTCCACTGGATTCCTCAGAGGACAGAACACAGCTCTGACTCCAGGGTGTGGGCTCACTGAGGGACAGGACAGGC
+
HI?B?CFID@EHAHGDHIACHA?ACC@EHEAAEB?CGCAI6EBHCBF?CE@H?IAI@ICAEBDIFG@AH@IDCBHBIGHBAFIF?CCDBFEACIEHFDGE
@>chr21:9904015-9904127-3
TCAGACGGTAATCAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGACAGAGCTGTGTTCTGTCCTCTGCGGAA
+
FIBD?IBC?HIAC?AEACDDBGAA@HC?CI?CG?GBICB@DEHCFDHIDACGCBHICC@EEHEECDFGAD@@<BEA@HGIHIF?GA??D@H@BBHHH?GA
@>chr21:9904015-9904127-4
TCAGACGGTAATCAGCATGGACCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGAGTCAGAGCTGTGTTCTGTCCTCTGCGGAA
+
EAAA?EGGCABDAB@I@@E@/@HAIIGBACAHCABADDBHDH@CIHCACIIFCAIGBBGA?EGDFBABC?IEBH@HHDA??DEGADBBFBHG@GBFGEDA
@>chr21:9904015-9904127-5
TCAGACGGTAATCAGCATGGCCCTCTCCCAACCCCAGCCTGTCCTGTCCCTCAGTGAGCCCACACCCTGGATTCAGAGCTGTGTTCTGTCCTCTGCGGAA
+
GFCIBD?HE?CDD?I??BIE@CGHGIFIFCEDF?CHAAICCHC@GGFADAEACIGG@IAHDDF@ICBBC??#HAIFCBAGIGI@EICB@HGACIECE@@I
@>chr21:9904124-9904223-0
ACCACTATGTCTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCATG
+
@FF?IDDDBFE@@GIHFAG?EEG@E@HE@CG@BFGCHGBIADG@AIBFFBEGDAFDF?CHH?AD@AB?@EDC@A?@G@BHDG?BCHBCGADEIICAEB?@
@>chr21:9904124-9904223-1
ACCACTATGTCTGCAGCTGGGCCANATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCATG
+
@GI?B???ID?IIBFEBEDB?B?F0BEBAAF?BIIGA?H?DIEGAFGB@HEIEFDCBCIFCIAAAEDBHCBCIEEC@A@IC@C@?FEIC@D@??D@GE?D
@>chr21:9904124-9904223-2
ACCACTATGTCTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGTTCAGTAACAGCCATG
+
EF?@EHHFBGBH@CIFFGEDI@DIHI?AGG?GADB@H@CA?CB@EBFEHDD?IA@FF?IIECICE@EI@?HI?I@DGHGH@H?C!@?BI?CCFDHFECBD
@>chr21:9904124-9904223-3
ACCACTATGTCTGCTGGCCCATGGCTGTTACTGTCCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGCC
+
BB@@@CFCID?GBAIC?IAGIG@CCIG?GAGAE:CGBIHAHIFHGA?BBA@ABGHBD@@EEHFHCIDHCI?GEFBCHDFEIF?G?A?HEH@HEIH?DA7A
@>chr21:9904124-9904223-4
ACCACTATGTCTGCTGGCCCATGGCTGTTACTGACCCGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGATGGGATCTGGCC
+
DICB@?IFFE@?E@AEHBG?GDHHIDAEFHAEABDF/CB?IF?E?AIHHDCBGFCGHDH@GABAFGIBDHGCBHBCE@HIE@C<?FE0D@EBCGI@FIDF
@>chr21:9904124-9904223-5
ACCACTATGTCTGCTGGCCCATGGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCAGAGGGGTGCNGGTGGGATCTGGTC
+
B@H@@ED@HCCADFHF?HG?BDAGAE@AECGE?AHCIB?BABE?CIGIHAGFIFHG@AHFGF?@ECIGCGCA?HG0C?CGCB@F?,?@AGECEEBAID;E
@>chr21:9904124-9904223-0
CTCATAGCACGCTGCAGCTGGGCCAAATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCAT
+
EAEDFH3BFGIIHD@?I?B@GFBGC9BIGFGDGD@FHFBBCAFAGIIII?AEBFGGDD?@IFAAECCCGHEGBA?C?DB?BDHI?H?E@B?G?HAHBECD
@>chr21:9904124-9904223-1
CTCATACCACGCTGCAGTTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCAT
+
E?H?CD???E?AA?IE?-DFIB?@H@FABB?A@HCACGD?EFHCEGACGEB@CIEFFAAAG?AEDDFAD?GHCDB?H@DA?CHG@IAGFAH@I@@BDFCG
@>chr21:9904124-9904223-2
CTCATACCACGCTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCAT
+
B?GDCBCBDGH@EAHEC@CHGHEG??HHFAGEBH@BAB@GFDCFEFBBI@HC?GBG?BGDA@CAGG?C@?FHCAEHC@BIA?C?IDEBAD?@@@FB?BFC
@>chr21:9904124-9904223-3
CTCATACCACGCTGCTGGCCCATGGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGC
+
CE?@AGAFEEHC?H?BGDBBIBE?@GD?AGADFEBAFCAFBDBDFC?/BCA?D?CGDEI?ECADID?AD@BDBFFFFADHHFDBGBFAHFIBDII@DAGB
@>chr21:9904124-9904223-4
CTCATACCACGCTGCTGGCCCATGGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGTTGCAGGTGGGATCTGGC
+
BCIA??HDF!IFGGGB@C?GFAABCIAB?CEAF?G@AGEEFHIBCBCI??ECE@FDHAAA@@CIF?ECBHIEAA?EIGGIGI7BBCDBFGCGIF>@C?BA
@>chr21:9904124-9904223-5
CTCATACCACGCTGCTGGCCCATGGCTCTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGC
+
DFDHIDECIGEBC@?AHCDCFHBHAFF=??AEDGHFAFAHIAGIEDHDBF@F?@?@DE@HF?FBDFDG?@BGF?BIBI@FABAB@F@EGBD@IGFDAGBH
@>chr21:9904124-9904223-0
GAAGGTCCTCTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGAAGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCGTGG
+
ADCGADFDCEFCFGB@IBBGGFCIEABBDGIGBF@FAAFHE?@DIA@HCII?BCHD?FF7A?AIFCFC@FDFAGDDDBBFE?CD@CHBDHFH@FDHEBDC
@>chr21:9904124-9904223-1
GAAGGTCCTCTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCATGG
+
?@CHCBGFIAHIHA?HAFF?EEAHEIEFEBD@HAIEIAAFDDBE?E@AABCEC@IHBGB?ICHICGGADIE@GAHBAFC@HGH?I?IBHGBGB@@@AI?F
@>chr21:9904124-9904223-2
GACGGTCCTCTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCAACCCCACCCTGACCCGGTCAGTAACAGCCATGG
+
IG:@CGHF??FCGE?FH@HECE@?4@F@GE@?BEFE@D@?ACCB?BADCE@AHFGEIE@?A@AEDCE8DGFC@DC@BBFA??E?AEDIIFAI?G@HFDBE
@>chr21:9904124-9904223-3
GAAGGTCCTCTGCTGGCCCATGGCTGTTACTGACCTGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGNCATGTGAGGGGTGCAGGTGGGATCTGGCCC
+
GDH@?DGBFIDAHCGDCD?D?@F?DBDH?G@GAFF,EGIF@I?DHEFCEAHGBH?I?IDFBDC@FBCCF3BED6EBCCEFF?IFDFHHBCDFDG?DFCCE
@>chr21:9904124-9904223-4
GAAGGTCCTCTGCTGGCCCACGGCTGTTACTGACCGGGTCAGGGTGGGGATNGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGCCC
+
CII@IEG???@EFE?AAGCC@A?G?FDDI@FCGEHAHFD?I@CC@@E?DDD$DBDFGB??H?CCCB?B?DDIB@E@IF@F?AII>FDEBFAIFEAH@?IH
@>chr21:9904124-9904223-5
GAAGGTCCTCNGCTGGCCCACGGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGCCC
+
?IB?D@A?FF5HI?+FED@DEACGAHHDAI?GG@@ICGE@HBCDBAGHECFIHEGFHCADEHICBBFA??DFGFE?I?CFEHDADH?BIH?@CE?CI?IA
@>chr21:9904124-9904223-0
GCGGCGTACTGCAGCTGGTCCAGATCCCACCTGCACCCCTCAGATGGCAGNGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCGTGGG
+
?I@DD?FCBDFDICHFCG$?@DDIDAFBDAFFHH?ECAHD@B?CABEAF@:BDGAIHFGEE4IBI?DE@FGHIAEDHHGAIGEIFCB@G@IBCA@AADGF
@>chr21:9904124-9904223-1
GCGGCGTACTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACNGCCATGGG
+
AGGCDBEBI@CHF@HF@?@GEDIDDEC?HGAIGGHBACGGAGCI?@DBH??AIEFCI@?EG?EDGH?H?GFICFGBGGEHCEFBD@EBBFB!?FBGH@B@
@>chr21:9904124-9904223-2
GCGGCGTACTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCATGGG
+
?CCIFBIAGDIB@FHHC?CDDCCHDCGFAGGGHAGDEAI@AAE@FFF?BABAI@BHCGCFC%HEFHCC?EHGGGI?HG@AFDI?@CEIDAE?IBB?HCCI
@>chr21:9904124-9904223-3
GCGGCGTACTGCTGGCNCATGGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGCCCA
+
?GEDCC@G@FIFHEGD/GA@I@IDHID?CD??HBECD@@D@@DG?EGBG@?DHIIHEDBFFIHGG@HDHC???FBDCH?@ICEBHF?D?GEDIBCH@H??
@>chr21:9904124-9904223-4
GCGGCGTACTGCTGGCCCACNGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGCCCA
+
HDFEICACEGFDE@IEAFBI:HCGHE?AFE?B?A@@GHEBFFBC@GBAEGDHEAHC?E@HDEIBC?DGDF?HAFCHFACCEDHIIFDCCIHCI@C@F?G?
@>chr21:9904124-9904223-5
GCGGCGTACTGCTGGTCCACGGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGNCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGGCCCA
+
CICBEC+GGHI?GBF/IG@@BGBC@IDHGBAIG?HAIAB@??GHGAHIBHGAGH?EI4CHFHGGFGIF@)?@CFEHIBIFIBEIGCD@@FBDHC?C??@E
@>chr21:9904124-9904223-0
TCAGACGGTAATCTGCAGCTGGGCCAGATCCCCCCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCG
+
AEDAHAIBEDFD?@IEG@IHEDDF??HAID?H*CDHIDIIFED@BDCHGAACD?HBAII?GIHDCB@AGDB@CDHBHIHCHEDDHCDAHCAH@FE?FABC
@>chr21:9904124-9904223-1
TCAGACGGTAATCTGCAGCTGGGCCAGATCCCACCTGCACCCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCA
+
F?CHD@@EIEHAFE?AE@EGCEBIHFAFFHIAGECD@GDFD??@ADGAFBHACA@DIEID@EDG?IGED?EF@BCDD?GGABGDEHHGBI@?IE?BFIAH
@>chr21:9904124-9904223-2
TCAGACGGTAATCTGCAGCTGGGCCAGATCCCACCTGCACGCCTCAGATGGCAGGGCCTGGACGTCTCCATCCCCACCCTGACCCGGTCAGTAACAGCCA
+
IBFAABI??BD$AECI??ECIAIBFIBECADDGIBFHDFE'@FECFDHBH?FAFAD@?GHC?BDE@DFDH?@AGD@EBCFE?FAC?@ADIID?BEF@GBH
@>chr21:9904124-9904223-3
TCAGACGGTAATCTGCTGGCCCATGGCTGTTACTGACCGGGTCAGGGTGCGGATGGAGACGTCCAGGCACTGCCATCTGAGGGGTGCAGGTGGGATCTGG
+
BFDCEGAB??FG@ACAC@H?FFEE??BBGHIHHFCGG?EAG@D@FIDBG-@BFG?FB?HAGFAIEFI@0ICIEBFAHAED@G?FDDB@A?BEDC?HDGAB
@>chr21:9904124-9904223-4
TCAGACGGTAATCTGCTGGCCCACGGCTGTTACTGACCGGGTCAGGGTGGGGATGGAGACGTCCAGGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTNG
+
GB@D@A@A?IICGGFEE?CA?B@B@@GDAGA@FDA@DICIH?C?FDGCHCAFI@?GA@@FF@H>IEGF?D?FCHCHHC?CI?I@II@@FFFICA?FEG1I
@>chr21:9904124-9904223-5
TCAGACGGTAATCTGCTGGCCCACGGCTGTTACTGACCGTGTCAGGGTGGGGATGGAGACGTCCACGCCCTGCCATCTGAGGGGTGCAGGTGGGATCTGG
+
FFGEBCBFCFGD?G?F?HDH@@FGACC@BFBBHA@CBC?+D@DAD?CGCCHH?IDEHEF@HC?@H,F@?CDFGAE?II@BCFFDHHF@GHDIHHEEEAFF
@>chr21:9904220-9904294-0
ACCACTATGTCAGCCCCCAGCAACCCCTCCCTCTGTGCACTGCGAAGGACAGGATGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCGAA
+
EBAIH?CIEAHCG@EH@BE?FB?HCDGDCAHBFCGCF%EGIHG9EBC?GGCFHH@?DGAEICDCH?I@G?GFEBFGGBFIEHEC?HGFF?FDHAI?I?@D
@>chr21:9904220-9904294-1
ACCACTNTGTCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACANGATGTACCAAAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCGAA
+
BABGGH/DFECDAIFDCCDHGHDEEEHEIH?DICFA@CCAEDGCG?IHGDC5IFIEBI?B@"EDDH@CE@CFFEFDFECCCIIEDAI@FG@@EE@CCCIB
@>chr21:9904220-9904294-2
ACCACTATGTCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGATGTACGACANTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGTGAA
+
IGIAHBGFIAEEIGF?FG@?I?GI?@EFIFAB?CCFAIDBAHFHF@@BBGBE?GAAEFG)FEH%?FA@BCEICDAGHDFEDCDAD?HE?@@AFB@E$IF@
@>chr21:9904220-9904294-3
ACCACTATGTCAGCTCTTNCCTGGAAGAGACTGTGGTACATCCTGCCCTNGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGAA
+
HGE?EGEAII?FC@ECCE(AABCCFDAFCC?AGCDADCDG??CCE"GHG.@IB@BBIF@DGBAGD?HDBE@HBG@EGIHIGIGABHBIC?FG@@?DII@B
@>chr21:9904220-9904294-4
ACCACTATGTCAGCTCTTGCCGGGAAGAGACTGTGGTACATCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGAA
+
CABFHC@EH?E?G?CH?DBEG1IHI@AAF@FACBCIHFHCIG@GECIGG@?ECIC@GCFGGC???FD@HDGFDIEE@E?DEHGFIDHBG@@?E?IFEIDB
@>chr21:9904220-9904294-5
ACCACTATGTCAGCTCTTGCCTGGAAGAGACTGTGGTACATCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGAA
+
EBGEHCEBIDABGEIIECHFHHDHB@ECDCE??DGHAA?EDGDHHHIAHAFHIDFIFAHBG?GHCFGG?CEBCGBE?HHBHIH?EAH@AI@FFG?IAG?A
@>chr21:9904220-9904294-0
CTCATACCACGCATCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGATGNACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAGGAGCGA
+
ICHBGCB@GFFHH5IEIA@?EC?GHCIBAC?DBIFA?I@ICH?IEAEFECAGIIEBE.AA@DDFGCBEGEHGEGB@??AF@EEEB@H?@ADE?$FDH?HB
@>chr21:9904220-9904294-1
CTCATACCACGCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGAGGTACCACAGTCTCTTCCAGGCAAGGGCTGAGATCGGAAGAGCGA
+
H?G?CBFEG?C@FA@@BHAIHE@HIIABHBBDB@@CF?AIDFHBBFCIAAGFGCCDIFBG?HCEAHBBDIHCBAGAGDDB5IDGEC?BFF@DECH@FCGA
@>chr21:9904220-9904294-2
CTCATACCACGCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACTGGAGGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCCGAAGAGCGA
+
GHCIHD?ABGH?IFHBIDHFBDIE@IBBHAGFCAD@IAACE@?GBCE@DFA6AEIGDBFICCA?EAAHFGFCDBEAFABHI4BG?HA?@F(@EEB?CG?G
@>chr21:9904220-9904294-3
CTCATACCACGCAGCTCTTGCCTGGAAGAGACTGTGGTACCTCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGA
+
BBCF?BBIFCGBG@EGGAGC@AEBG?ACDI?F/DEAB@H@A?DID@A@EIFGABCC?D@GB?BEEAD@G?EB@@HFDIHH@DIE?FDH?G@BFE?BIBF@
@>chr21:9904220-9904294-4
CTCATACCACGCAGCTCTTGCCTGGAAGAGACTGTGGTACATCCTGTCCTTGGCANTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGA
+
IEB@HFDGGEEHGAC?HDCE?@E@FEDA@GBHFBBG?DEIGDGHGAGEAGDHAC?6A@HHDBCGF?BIAHAHCEB@AGBCHGACHFBGADIG?BH@A@A@
@>chr21:9904220-9904294-5
CTCATACCACGCAGCTCTTGCCTGGAAGAGACTGTGGTACATCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCTGAAGAGCGA
+
EFIIABCHDIE?B?HC?DHD@?ECFBHDH?BDD@FAICAFDIAH?CCAECIF?CFGDDBFICHCGAAFDC?DFFGDGAFA?EFC@EIGAH6EGB?EDGGH
@>chr21:9904220-9904294-0
GAAGGTCCTCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGAGGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCGAAA
+
IIEAAHAEED4@DCG@@E@DEEDDDEC?GDHBC@CECAEG?A@I?FDHIHGEEHB@HCII@ICBDIE@AAICF?FIABDDGA@?D?B@DF?CACH@EF@G
@>chr21:9904220-9904294-1
GAAGGTCCTCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGAGGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCGAAA
+
AFGEFIDEGEEC@AC?H@IFIGAH?H@?IDGCGGFD@DHGGFGIG?GGI@ECGAEFGIEH?CCFDGECGGHE@G??HGH?I@C?@FD@BDHFGAABHAGD
@>chr21:9904220-9904294-2
GAAGGTTCTCAGCCCCCAGCAACCCCCCCCTCTGTGAACTGCCAAGGACAGGAGGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCGAAA
+
BF?H?H5DBD??I@AIEGHAHDFIAB,H?FCAIAD@?EGIACDHIFCC@EE?GDFI@CA@EG?IFIBFCIICDIAIDFBA?C@D?HFG@?GI?GGEC@BD
@>chr21:9904220-9904294-3
GAAGGTCCTCAGCTCTTGCCTGGAAGAGACTGTGGTACCTCCTTTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCAGAGATCGGAAGAGCGAAA
+
AD@@0B@GGCFH@?DABFF@HCBD?@@BAHCBD?EDBIHAGIH'ABDFHCGBIIAGGE@CEBAF?HECEGDFCDBGIBCIA/CA?DAFEGACDIH@BBHI
@>chr21:9904220-9904294-4
GAAGGTCCTCAGCTCTTGCCTGGAAGAGACTGTGGTACCTCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTACTGGGGGCTGAGATCGGAAGAGCGAAA
+
BHEAG?DF?D??@?CDHBHFADB?E@EFFB?IEIH?CHAHECAFCD@DAIADFDEEIIGE??FIFGCD?CFA<EGGC@??IGDFA*ADEEB@IC?HF?II
@>chr21:9904220-9904294-5
GAAGGTCCTCAGCTCTTGCGTGGAAGAGACTGTGGTACCTCCTGTCCTTGGCAATTCACAGTGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGAAA
+
@EAIAGG?DE?GIGEABGA/AHHFAAGHIGAADD?@DDGCEEEDDBFE@BAHF8AIEDHC?$I?DEFIHHIB@G@DAEABA@@A@DFBF@GG@H?I?EHF
@>chr21:9904220-9904294-0
GCGGCGTACAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGAAAGGATGTACCACAGTCTCTGCCAGGCAAGAGCTGAGATCGGAAGAGCGAAAA
+
H@I?HGC?IEIGGF$?FFHBAAH@?DBGIFICDI@BBIHBFFABFBE=AH@FFDI@IBGBEFIIEGD*E?HD@BD@IIBD??B@ICAE@AEGG@CEIEF@
@>chr21:9904220-9904294-1
GCGGTGCACAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGATGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCGAAAA
+
BBAB,F(GBAHDIBAEFIG@?DD?FDEA?HB@IHEBDCHGE?EGHIFCABI?DAB?E?CEFGB?IDCGID@A@AD@FDDHA?GEBDEDH?CACGCDIEC@
@>chr21:9904220-9904294-2
GCGGCGTACAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGATGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAAAGCGAAAA
+
??@?I?ED@@E?IFEGHIIGBGFIDF@FAC?@CE@HF@?HIBHGGBFB@FDC@?CFHEIAGH@?HCDFECHBDAC?)H?H?EHI@IBDFBD;HIEA@C@I
@>chr21:9904220-9904294-3
TCGGCGTACAGCTCTTGCCTGGAAGAGACTGTGGTACATCCTGTCCTTGGCAGTTCACAGAGGGAGGGGATGCTGGGGGCTGAGATCGGAAGAGTGAAAA
+
;A?E?D@D@CH?EG@@FHGCDHHAHF@ABIHDGGCCIHD@G?ADFDEBDIAFGADCAIBF?GAACFFCA)IGDB?A@IEG?GDF@ICF??@EFH(H@@@G
@>chr21:9904220-9904294-4
GCGNCGTACAGCTCTTGCCTGGAAGAGACTGTGGTACATCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGAAAA
+
C?F1CAIF?D@@DD?HAA?CHCDIAACBAGFD@AIAAB@@?IDCBFCA?ABA@EAIDHFDIGG@CBGDAB@GI@DA?@CB@?HIBEIID@IHFHBIHIHI
@>chr21:9904220-9904294-5
GCGGCGTACAGCTCTTGCCTGGAAGAGACTGTGATACATCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCGAAAC
+
C?ECECAGA??H?IIDG@FACBBC??F?GIFBD1GCE@GHD@CIHCIBHEDC@E@AE@H?FADECHEH?ADHI@IC?CHDEDD??IAAAAFGGB@GG@?"
@>chr21:9904220-9904294-0
TCAGACGGTAATCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGAGGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCG
+
FACE@@H?@DBEFG@@CCDE@?HFAECGBI?GHHBBEIHIFCEDAIA?GGIH?HBHICF@CHE@7HAB@D=BGFEEHBD?HFI?DGBHECDFBGAFGG@@
@>chr21:9904220-9904294-1
TCAGACGGTAATCAGCCCCCAGCAACCCCTCCCTCTGTGAACTGCCAAGGACAGGCGGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCG
+
?EEGBFA?FF@?AI@I@F??C?GGGBAEAB@CEDABGE@@B?HDBB?FBDHG?@B*BCGE@G@BG?@HGEHHBC?CB?@D?B@A?DIDIFFEE?IFBCGG
@>chr21:9904220-9904294-2
TCAGACGGTAATCAGCCCCCAGCAACCCCTCCCTCTGGGAACTGCCAAGGACAGGAGGTACCACAGTCTCTTCCAGGCAAGAGCTGAGATCGGAAGAGCG
+
D??DH@IF@@IFE@0@FH??B?D@DBGFBCADFDIFF:GEIGDFEDCGDHAAAGFBIEGADE?I?C?HBBEIF?IBICFFG@HGCFHF?BEDHFDGF@CG
@>chr21:9904220-9904294-3
TCAGACGGTAATCAGCTCTTGCCTGGAAGAGACTGTGGTACNTCCTNTCCTTGGCAGTTCACAGAGGGAGGGGTTGCTGGGGGCTGAGATCGGAAGAGCG
+
?@DE@DHBCFDFGBDBBBHHE@?ACIFCF?CBEAAIHGG@H;BH?E0HGB@@HGGG@CAIEHIG@BGAFEFDFEB@@CBACA?A?F@HG?IEH@A@BICC
@>chr21:9904220-9904294-4
TCAGACGGTAATCAGCTCTTGCCTGGAAGAGACTGTGGTACCTCCTGTCCGTGGCAGTTCACAGAGGGAGGNGTTGCTTGGGGCTGAGATCGGAAGAGCG
+
ACECHED?AD?H?I?GIF@BAECEFHFFAEAHGDB?IFIGC@FIEHGAFC:AGBGFI@GECIADADGBBEA,AE@DBF7CACG?FGC@IAIADEAH@IIF
@>chr21:9904220-9904294-5
TCCGACGGTAATCAGCTCTTGCCTGGAAGAGACTGTGGTACCTCCTGTCCTTGGCAGTTCACAGAGGGAGGGGTTGCNGGGGGCTGAGATCGAAAGAGCG
+
GG4EB?EAFIEDEFCGGF?EHFE?AAEB@HCIAHD@CABFDCCDDGDF@FFDHEHC?EEBEFBGAGDHEA@@HGGG@4EAIHI@@@?GFCIG%ICECCC?
@>chr21:9904534-9904635-0
ACCACTATGTCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGACAGCCCTTAGGGTTC
+
F@@E@II@FGF?FAHFEDI@H@@GDHDHHBIFACAI@C?FIBIBC@C?ACHA@B?@GG?E@?GFAAF@BFE@DIAICDFA@@EF@D?BDFCIHFBDDFEE
@>chr21:9904534-9904635-1
ATCACTATGTCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGNTCAGCAGGGAATTCAGCATGAGGAGACAGCCCTTAGGGTTC
+
D.HFDGA@@D?BHFFBCGGCCIF@FDECEGII?HCIIDEA?GD@CACDABII?@BBHA6GIFGBEFB??@I?GDBFHBCEDGBCFGGBB?G@DGIEGFHF
@>chr21:9904534-9904635-2
ACCACTATGTCTGCCAGTGTCCAGATGGCATCTGTGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTNAGCATNAGGAGACAGCCCTTAGGGTTC
+
I?CIEADHDIDCEGGBE?@?IH@HEDF?@;HH<G;CCCF@B@?EICFAEFFE@EDFEBA?BGHCH?E?FD)C2CAFIA%?FG??DEAGFIH@EEDEIGDA
@>chr21:9904534-9904635-3
ACCACTATGTCTGCTGGGCCAGAACCCTAAGGGCTGTCGCCTCATGCTGAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCTG
+
@BHEICB@AEHFHBDD?@FEIDCGBA@I@BHBDIIDE@:CAHEDFEF?@CCIIDCIAGGCGFDHCEH?BCEGFEDFH?C?GGI??@?GAEGF@B@?@@HF
@>chr21:9904534-9904635-4
ACCACTATGTCTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCTGAATTCCCTGCNGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCTG
+
E?CGFEEC@?FDGHDEEDFHAEHEIF?EGGHD?AGB?@?A@DCA?@F@HIAGIIEDBBH5@GACHCEB?HAD?IAACAACI@DHEHADGCIE?GHAH@CI
@>chr21:9904534-9904635-5
ACCACTTTGACTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCTGAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCTG
+
DFIGDD,FG;IGDHECF@HH@FAHA@ABGHAFBB@BCB@IH?G@@FHAGHEBIHEHGBB?BBHHCDC?@F@G@CEIDECEBCGI?IH?B??G?BA@A@BA
@>chr21:9904534-9904635-0
CTCATTCCACGCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACANTCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGACAGCCCTTAGGGTT
+
BFADB8?DBDGCIIIABCG?FB?FGHFFDHGBAHECGFBH?D@?IIBIHFH&GH@FEGDIFAB??EI@IC@GB?IDGAAE@DIEGCBDG??IIFIEHGAB
@>chr21:9904534-9904635-1
CTCATACCACGCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGTGAATTCNGCATGAGAAGACAGCCCTTAGGGTT
+
EDAI@FHDEEDCHBFCA?GHCGDD@F?CC?DF@IDGIIGCBHGCECHIIFAEEBFACGEBIEG??HG3HFF?C?&FEBIIABI?CH@GFCD0BAI@DFGH
@>chr21:9904534-9904635-2
CTCATACCACGCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGACAGCCCTTAGGGTT
+
C?G?E@@CHHBIDAACA?ECHEEHEEI@GCIFBABE?BGCE?ABIIEFE?IGGCHE@HIGDF?EFDFGDIAFCD?BBBGF@??GE@AH@BBAA?B@D@CB
@>chr21:9904534-9904635-3
CTCATACCACGCTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCGGAATTCCCTGCTGACCTCCANATTGTCTAACCCCCACCCCTGAGGCCATCT
+
HGGCGA?GB@CDHGDIIG?CCGHCEDECCD@EBIC@ICBCACDEGBIG:@IGHGDHB@DABCBEBGEGC6IHDCIDF@C?FFA@EBI@CEGABGB?F@IG
@>chr21:9904534-9904635-4
CTCATGCCACGCTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCTGAATTCCCTGGTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCT
+
ACI@E2DHDEIIC@FA?BGGIBCDEBB@BHHIDIB?CHFHGDG@@?GAD@DDGB@D?CE-CCHDCE?HIFDGGIAEC?CIAHAEBC?HII@?ICHEG@EF
@>chr21:9904534-9904635-5
CTCATACCACGCTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCTAAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCT
+
B?FGE??BF?DBC?DF?BHIAC@EHEHBDI@BCABHBI@AFICIHBDA@=BIDH@GE?IADIFGEA?DBE???G@EFBAE?CHI?ICAHF@B@@FAGICF
@>chr21:9904534-9904635-0
GAAGGTCCTCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGACAGCCCTTAGGGTTCT
+
DAABEEH?EBBA?ACHI@?EE?EDGABF?H@HFA?BACHACFGG?CDAGCAHBB??HGG?ACCFE@BFF@DCC@DGCAFIHHEBCAAFAIGCICGF@IHH
@>chr21:9904534-9904635-1
GAAGGTCCTCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGACANCCCTTAGGGTTCT
+
DAAFEI?FIBG@@?BEECEI?AA@D?HAEGBBII?I@ADEEF@BCFEADBI?I?FGEEIIGD?@IDDIF?GF@ECD?BDFGGAI@G<?GCAFD@BF@BH@
@>chr21:9904534-9904635-2
GAAGGTCCTCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTATACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGAAAGCCCTTAGGGTTCT
+
IC?E@BDGG@I@HBF@ICGDBCBCCDCG@@EIGCHEGCHBB?CBA/EEF?GFAF@IFDHGDDECF@B@DBCB?@?GCAIGH@HB)AFDIEBCCHCCAH@B
@>chr21:9904534-9904635-3
GAAGGTCCTCTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCTGACTTCCATGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCTGG
+
BCEB?BBCCB?DB@AI?GA?HI@AEGBGAE?@@IEFEGE4F@EFACCEA=CFCH=ADD?I@@@BB@BEAIDIA???H?G@HIDFHHI@BHADGFCIDDG?
@>chr21:9904534-9904635-4
GAAGGTCCTCTGCTGGGCCAGAACCCTAAGGGCTGACTTCTCATGCTGAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCTGG
+
C@?GADHDB?BGAB@EHFEA@CGGEECH@DGIHEB7@CBI?@AI?GACEG@HHEHAC@ID?EACEHGEIGFBHHAD?IFAHHCF@C@HIICGFCEDGB@F
@>chr21:9904534-9904635-5
GAAGGTCCTCTGCTGGGCCAGAACCCTAAGGGCTGNCTTCTCATGCTGAATTCCCTTCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGNCGTCTGG
+
BFEHGIIAAGIDIHAG?HFG?DCEBI?GAFCGHED.AGAGFEIBHE?DGD@B@?@I.GE?HFDDIH@FHHH?CCA@DFEAGG@CEH??HHAD"I+IDHAE
@>chr21:9904534-9904635-0
GCGGCGTACTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCANCAGGGAATTCAGCATGAGGAGCCAGCCCTTAAGGTTCTG
+
@G?AE@EI@I@BCGFBAC?GBEIGBFAEICBEAFDHBFDIBACDCHBGE?EDA@A?@BH@4I?GDCGFCEF?HFDF?AFEAC/CFGIHEF@D6D@F@GFA
@>chr21:9904534-9904635-1
GCGGCGTACTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCGGCAGGGAATTCAGCATGAGGAGACAGCCCTTAGGGTTCTG
+
@DIFB@GFCFIBI@DA?HDEECEII?AACCE@@@HDIFECDDCDFHHDBA?AHCEIGDB!HADBIDD@GIHA?@CHHF@?F?GHG@HD?DCHHEF@GBB@
@>chr21:9904534-9904635-2
GCGGCGTACTGCCACTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGGAGACAGCCCTTAGGGTTCTG
+
BA@DI@GBACD@G?$A@G@EGGCGGGD@?AG@EBCGIEDBACCCCAI?DCADBFHGFBHIDHGBBBFFD?D?@AGHBDF@AH?IIHFACA@A@FCB?DHH
@>chr21:9904534-9904635-3
GCGGCGTACTGCTGGGCCAGAACCCTAAGGGCTGTCTCCTCATGCTGAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCNCCCCTGNGACCATCTGGA
+
E@IBH?F@BBH?BIEIHG@DA@C@AEGB?BDHDFBIGCCIGBEGAAIE?IB?C@HC?CEE?IIF@@AI@HCAFBAIED?IA+IF@FID,H!FABEDDAAE
@>chr21:9904534-9904635-4
GCGGCGTACTGTTTGGCCAGAACCCTAAGGGCNGTCTCCTCATGCTGAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCTGGC
+
FG?B?DICEGE0B>@AICC?@HCBIHIDA@DH&AB?F@@DAAIE@DCGCG@AFIEECHFDD?HIBGAIFBAFDIIBCEAAFIC@HCFG?BHG@BAE@HF3
@>chr21:9904534-9904635-5
GCGGCGTACTGCTGGGCCAGAACCCTAAGGGCTGTCTCCTCATGCTGAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATCTGGA
+
GEDHCBGGBFIIEAFI?@CH@FAFDHCBE@@?FG?IAE@D?@@G?BHHBAGDCDGAFI@6BB@EBA@ABEFAGCGA?BE?FGE@IEA)FCHGGDDFCIGC
@>chr21:9904534-9904635-0
TCAGACGGTAATCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGACAGCCCTTAGGGT
+
?IDA?B@GBB@GEC@ADH@EC@GFEHDAG?EFCDADBHCEGDACAHD?DFIE@?DHEGBGBHGCFIEGHA@?A@DBII?FHDHH@GCGEH@CIEI@IIE@
@>chr21:9904534-9904635-1
TCAGACGGTAATCTGCCAGTGTCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGGAATTCAGCATGAGAAGACAGCCCTTAGGGT
+
CABCBHC?ADFICDHCC@ECDEE@GIBFBCABEF?E@AGHEHHBIEFCA??DD@FDDHB?BHBIIEDHCHIBIDAEBGHC@FA?AACIFIDEDED@?H?I
@>chr21:9904534-9904635-2
TCAGGCGGTAAACTGCCAGTGNCCAGATGGCCTCAGGGGTGGGGGTTAGACAATCTGGAGGTCAGCAGGTAATTCAGCATGAGAAGACAGCCCTTAGGGT
+
@B?A(EB@HHH<CFFCFEBCH2BEF?AGA?IEDHCDFGBGEDG@EABHIEIAIICCAFDE@G?D?DCIA2D?DIFE@EIHHF?BIHF@GHAI?GDIBEGC
@>chr21:9904534-9904635-3
TCNGACGGTAATCTGCTGGGCGAGAACCCTAAGGGCTGTCTTCTCATGCTGAATTCCCTGCTGACTTCCAGATTGTCTAACCCCCACCCCTGAGGCCATC
+
AD#??EIDIHIIAE@ECD@DB+D?AG@IAFBAAADHAEEA?H@DGIFGDBCHAFG@BE?CEI@CB"DHIGDDF?DDBHIGFF?FCBBFGCADEG@AEFIA
@>chr21:9904534-9904635-4
TCAGACGGTAATCTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCTGAATTCCCCGCTGACCTCCAGATTGTCTAACCCCCACCCCTGAGGCCATC
+
CCG?D<GGGB?FI??DAC>CDAC@?II@GDCDIC?EDCFI?G?GIFC?AG?AD@CAIE-FCC?FD?FB?FBBEHBIEHI??HIGGD??BFIC@DEAFHC@
@>chr21:9904534-9904635-5
TCAGACGGTAATCTGCTGGGCCAGAACCCTAAGGGCTGTCTTCTCATGCTGAATTCCCTGCTGACCTCCAGATTGTCTAACCCCCGCCCCTGAGGCCATC
+
ECGICABHDACGE?C@@EFBBEBGDGBH?H@AGFEGEDEIEHH@FBI?HF?DA@AFAI??E@C@AFG@?ECBD?AE@BG?IBGHA7FED?DEACBIAHCF
@>chr21:9905043-9905159-0
ACCACTAGGTCAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTCAGTGGCTAC
+
HEDGIEG$?C@FDIF?DDHHGCCHDD@ID?IAIA?A@BAD?ECFFDG@BII?CHIIFDIIF@@EIAAGA@HIBB?EHFGBHCFBF?HDIH6CDAGAF@AG
@>chr21:9905043-9905159-1
ACCAATATGTCAGCGCCACCTGGTCCTGGGCGATAATGGCAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTNTTAGTGGCTTC
+
HGGI=BAIHHEAFAEBEHGG?FH+DFIFFIFFGECC?@?7CE???ADIE?AIFCICG@EH@CFDFDHCDFCH?AGIFGHGHHCH?III9GC@@DAAFC!A
@>chr21:9905043-9905159-2
ACCACTATGTCAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTAGTGGCTAC
+
HDBDHFFED!EBIIFE@HAI?FGGBCADABBGFDIH??ICIEHAGIAFGDHC?CFEHHDGDGIFFHAHBDI@?EEIC?FH@FHIFG@??IIDA@6HEGE@
@>chr21:9905043-9905159-3
ACCACTATGTCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCCCA
+
GCCF@DADIIAAICCBDCCBCCBDDIDDIB?A@@?BHICIGC@GFBGGIIEHBAGDI@HIDHH?IDBAGEI?ACAAF@?IG?CEFIHFGGEEHGCAE?DI
@>chr21:9905043-9905159-4
ACCACTATGTCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGGCCCACACTCAGACTCCCA
+
BCHECAID@AB@@@FDHA?GA?FHEDBDIII@CF?@AGHDBIECCFDIFFAB?FHBEAFHH@FIAAED?HIAIH??CIIEA9GFI@GEA@G@A>D?EH?D
@>chr21:9905043-9905159-5
ACCACTATGTCAGCACTTCTCCCAGCCTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCCCA
+
GEHAFC?DBA?DDAAHGE?@@?F@D7DGAGCABFEH@CIEG@GB@HHBDG?F@CFE?BABCHEBADC@CBCBG?BCD?GBDFD?AI?HFHBGEECDAAIE
@>chr21:9905043-9905159-0
CTCATACCACGCAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTCAATGTGGGGCCTGCATGGGANGAGCCAGTGTTTCTTGGGCCTCTTAGTGGCTA
+
H?HDAECGB@IAEAC?GFC?HGCEBECB@7D@FCB??BBEHDCI@G!F=HC@FDEB@IIECHI@I2D<FGHDF@7GFHEABDCHI@DICGICCBBCI?BE
@>chr21:9905043-9905159-1
CTCATACCACGCAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTCGTGGCTA
+
FBBAH?E?IDIAE@IGCF?IFI?IBCE?IBAAD@AEHIGA@CH@DEIBHICBBGGADFDGI?DHH@I@GADCIEB?E@HFCDGD??IBECAB"@AIC@EE
@>chr21:9905043-9905159-2
CTCATACCACGCAGCGCTACCTGGGCCTGGGCGATAATGGGAGCNTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTCGGCCTCTTAGTGGCTA
+
?F?EDFFIADG@?BI@";EA?BGIFFIFCF"DFEG@BCED8GIG9@EFAE@GBGGAHFBC?@HA@E@?@DCGGFB@I@C@IE@'CA?CGHHIIFHIEBEG
@>chr21:9905043-9905159-3
CTCATACCACGCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCACGCAGGCCCCACACTCAGGCTCCC
+
@HCF@GDA?EEH1@BFHCHBB@HFBBEIHHHDDIF@GII@@FC?CBCBDEBG@CDHDEAF?ABGAC@GFBFG@AAI4FADHBF@CDACIEFED?G?G@HG
@>chr21:9905043-9905159-4
CTCATACCACGCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGCCCNACACTCAGGCTCCC
+
FDHICDDB@EAFBEHCFEDFG?IFDD?EEI??HD8DGGGE@DHHCIGCEBGIHEBCBHCDAEEICC?FGC@IIECGG@HAIE?B?3?AIFAGA@D?BIFE
@>chr21:9905043-9905159-5
CTCATACCACGCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCACGCAGGCCCCACACTCAGGCTCCC
+
DDHBC@ABFGIH@GICH@BGBDEEGB2I@?DDIAG?A?BHFADIIEIHIFGDCHEIBAHEBEDDC@DDFGCAI?II*I@EIFDH@@ACHCADIC?GAGDA
@>chr21:9905043-9905159-0
GAAGGTCCTCAGCGCCACCTGGGNCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCAATGTTTCTTGGGCCTCTTAGTGGCTACT
+
BIE)FH?CICB@EFFEADCDHHF9GDBFDBEBDCDDIEFCBDFABIC?A3ABFF@IGAABHHFHFI?AFHB@BABBIII?GBFEAAFACIC@II@CGIHB
@>chr21:9905043-9905159-1
GAAGGTCCTCAGCGCTACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTAGTGGCTACT
+
C?ABHIEFCCB?EH?-A?CF@A?HEIECH?FAGFB@?@CA@AH@GFH?@E??AGECG?BDD@?ICCGCCAFE?BIFH@FHI?CIIDDDBC@IDE?BII?I
@>chr21:9905043-9905159-2
GAAGGTCCTCAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTAGTGGCTACT
+
GCEFGFGFEBH?HFFDCFDCHA@FEB@HHHHFF@BGBDCI?AI@FDIIEECAHGDI@IGFGCBBIFHD@BDGFCFBICHIHGGCIACAGCIDDCF@CFB@
@>chr21:9905043-9905159-3
GAAGGTCCTCAGCACTTCTCCCAGACGCTAGGGAAGTAGCCACTAAGAGGCTCAAGAAACAATGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCCCAT
+
IHAEDDDBGCIFDAC@D?ACA@DA@?(CIHBDH@DEHE?B?HGHHHGG?BG5E@B@EA?CCCI@??@GGG?FE?AF?IHGBGADEGE??AID@FGHHCDG
@>chr21:9905043-9905159-4
GAAGGTCCTCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACATTGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCCCAT
+
BHEFGEBDD@DIF?EDFGB@?FCGFGIH@ABIHEBBFCEBE?ECAA??EHAGHEHBIABIEIGEDGFEFCC@AGFDFBAGGBBHHEFHIDBHA?@ED/D@
@>chr21:9905043-9905159-5
GAAGGTCCTCAGAACTTCTCCCAGANTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACATTGGCTCCTTCCATGCTGGCCCCACACTCAGGCTCCCAT
+
@GHA?????AAE2D?C?CBC@ICFD1DD?CIFEDBIGCHAHGCG?DBDDIHG?ICH?HCBIC@GEIDGFHEAEDEED#@FHDD?GDIABGIAGDG?FHE?
@>chr21:9905043-9905159-0
GCGNCGTACAGCGCCACCTGGGCCTGTGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTAGTGGCTACTT
+
C?A$?G?DEGFCDEHE?@B?IAGC?H,EGGEI?CFBIFHI?FH@?IG?G?IAE?C@EI@BBBB@GGCEIIED?FHGBIDID@CCCD?DAFBCCBGBAE?H
@>chr21:9905043-9905159-1
GCGGCGTACAGTGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTATCTTGGGCATCTTAGTGGCTACTT
+
@FHGI?IFBII<I?ICBECC@EEDCBDA?FEBFFEDAFACIDCFFHDGCBFAEDDGCC?DCBGHG?@F?BAFGAH(GAIIGHIA!IBIH@IAAE?HFDGA
@>chr21:9905043-9905159-2
GCGGCGTACAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGAGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTAGTGGCTACTT
+
IFFAHHBGIGFAGE@EHGECD@IGCBB??CEAGAI?BFI?GEAHFAAF#?$BGDGHCAGIH@BEFFAIHCCCCAEAFFEBC?BFG?HIHDGHG@BBFEIH
@>chr21:9905043-9905159-3
GCGGCGTACAGCACTTCTCCCAGACTCTAGGGAAGTAGCNACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCCCATT
+
EEBEIHDBAB?C?EF?E?G?EH)A?CEC@BDBFFHB?CC;BICAE@B@GCHCBGF@FEBIHGFC@?@IDGGDGFG?FI?I?BIIEDB@BC@EIFCB@AE@
@>chr21:9905043-9905159-4
GCGGCGTACAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCCCATT
+
EEA??IGC@HEFFEBAEC@FCGICEC@@IEFDFFEB@H?HDFB@GHFG@EEIGDGAB@=@ICAAFHFHBEFA@FBGE?CHIIDBACCG@HIFFIDGGC?D
@>chr21:9905043-9905159-5
GCGGCGTACAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCCCCTT
+
ADDCIFICI?@IA?G?CDIG?"IIBCB@B@??IBDDH??IDB@?D?ABAFEA@FEGDDCDE7D@EGGEGIFFAIADE@GHHHC@EF@@ICGIEI?D?7BB
@>chr21:9905043-9905159-0
TCAGACGGTGATCAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAAGAGCCAATGTTTCTTGGGCCTCGTAGTGGCT
+
B@BDIFEHA6IHIF?@?CDBE?FH@CCEHCI@AHFEGFCEGIA@BBFFDIAFFCA?H?CCAHH@?FIG2G?CDH?AGHF@E@EII@D@D?I;HH@CBCC?
@>chr21:9905043-9905159-1
TCAGACGGTAATCAGCGNCACCTGGGCCTGGGCGATAACGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTAGTGGCT
+
IDG?@CD?BFBG?F??F-BABBBIFDDGBHAIBDBCHA(BCE??ICEGEAI?C@IHIEIC@HD?FBICAHIEBF?AHAHGF?DCHGCIF@@CHEGHIAIB
@>chr21:9905043-9905159-2
TCAGACGGTAATCAGCGCCACCTGGGCCTGGGCGATAATGGGAGCCTGAGTGTGGGGCCTGCATGGAAGGAGCCATTGTTTCTTGGGCCTCTTAGTGGCT
+
?@BEGIDD?@IEHEFEAF?B@C@HFGAAD?CAIEHEG@EABCGGAIGH?@@HBDA@@IG@HBABEIGGAF??F@FEGHEBHCFCFEEIAG?AEADCE?CG
@>chr21:9905043-9905159-3
TCAGACGGTAATCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACAATGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCC
+
?D??EFIEII@G?BAIAIEBBHDI@GA?DFABEAGCAI?CIBIDI@EEFFFFEBAHBHD@A?GCEAFDH@CBEACG?A@DC?IHA@@BF@EBCGBAFGFE
@>chr21:9905043-9905159-4
TCAGACGGTAATCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAAGAGGCCCAAGAAACATTGGCTCCTTCCATGCAGGCCCCACACTCAGGCTCC
+
F@BEF@CGF@FGCD@DFGCHID@IEB?BFCB?DHDHEBEC@?GDA@F@CHIIE@HAEGFD?CDEFEHC@IBAECIGCEB?GFCHCEHAGADIIE@GHC@B
@>chr21:9905043-9905159-5
ACAGACGGTAATCAGCACTTCTCCCAGACTCTAGGGAAGTAGCCACTAANAGGCCCAAGAAACATTGGCTCCTTCCATGCAGGCCCCACACTCATGCTCC
+
=FE?DCE@FEDAAIHCHDDEA?DDD@CDFEBIDHE@A?FBGEHC@ICAA&@EGFDID??DHAACCGF?@CIHFCACGEEHGIBA??AAIA@?DI1C@AGF
@>chr21:9905183-9905346-0
ACCACTATGTCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCAGGGAGGTTCCTGGCTCTCCTGGAGGACT
+
FBGGHBBH?@EGAAAAAAEGIIFHBH@BIBFEDBGDECHDH@CGFGHHE?D?AE@DBBACEBGCABGDBCGB&F?F@EBGAAICCDFC?GAFIADEGBBH
@>chr21:9905183-9905346-1
ACCACTATGTCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTTGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCNTGGAGGACT
+
A@C?GE?@ABGI?II@DGGEDCE@?ACBGGFFDABG)@HE@HA5BBFI@A?IICEAHBH@?BGG?CHCGBDH?IBIAGIEFF?FDH?F@D1@AC@DBE?D
@>chr21:9905183-9905346-2
ACCACTATGTCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTNACCTCTACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGACT
+
@C?FA@FFFBH?EFA?DEAE@ECEGH?FGFDGBCIBDHHCIDIBFCIG@HIIB:AIAHF.@H-IAFGGDFAFAAG?IBEEFEADEIDEEEG@BFHEEFGA
@>chr21:9905183-9905346-3
ACCACTATGTCTGCAGGGGGATGCAGGTNGTCCAACACCATCCGGGGACTGGTCAGCCCTGGTGCCGCAGCCCAGTAGCAAGGAGTCCACCAGGAGAGCC
+
ICFA?D?DFDIF?IAGDAB??C?FB??G8A@?C?EAA?DCBDF"E?AEDCHAABDE?CFEBEBDGB#EHFGBFDHGAI?BFBHHI#BH+E@?DEI%I?FE
@>chr21:9905183-9905346-4
NCCACTATGTCTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGCACTGGTNAGCCCTGGTGCCTCAGCCCANTAGCAAGGAGTCCTCCAGGAGAGCC
+
.FBEGCH?GBCFGHGGDCFEAHBBDE?CIADCGBDGA'EHICGCIA6IBD:H@8ACGAGEF@@FCAC?IEFBHH1?A?B?FACCCG??DECH@BIE@CFF
@>chr21:9905183-9905346-5
ACCACTATGTCTGCAGGGTGATGCAGTTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAGCC
+
C??IEEDDGIBI@BHFBB0FBEFGID:CFIFIC@FE?IFAEC?@@F@FHHDGBEBBBAI@HBACGGFA?GAFID?DEEH@IBIFIBEEHHDEDEH?@AEA
@>chr21:9905183-9905346-0
CTCATACCACGCAGCTCCTTATGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCAGGGAGGTTCCTGGCTCTCCTGGAGGAC
+
D?@HBIEBED@BEDCIDECAIC@FGCIC?GDHB?@CFC@CAHFCGDEEFHBHCHFCGA?FC@IGB?GBC???E"I@?CIEH@@@BACDDDFDC@??FI@I
@>chr21:9905183-9905346-1
CTCATACCACGCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGAC
+
CIC?BBIBCF?BF@IA?C?EBFAAGIHHDBDGEABDC@CEA?D/AHI?HCHG@@HDIBEFCBCHCBDE@@GHAAB@FGECIH?IHHFBHFFFAFHEFCF?
@>chr21:9905183-9905346-2
CTCATACCACGCAGCTCCTTCTGAGGCTGGGGTGCGNACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCNGGCTCTCCTGGAGGAC
+
??CCHB?HC@?BDDCECBBFGH?I?GHCBECFGI5?;GFIC@EHF@D@FEHDGFFI@@??@GGABF@HG@EDEDB@ADICAEH$IG?@HG@@AGGHGIAG
@>chr21:9905183-9905346-3
CTCATACCACGCTCCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCACAGTAGCAAGGAGTACTCCAGGAGAGC
+
@ADGHDEDH?GIC-EDAHEGBEHE@DE?GB@HHABFEEIF@@IDAFHBGBI@AB?@DFFBFEFA?I?FFEIC7GE?BGHI?B?@E@F%HFG?BHBIG?BA
@>chr21:9905183-9905346-4
CTCATAACACGCTGCAGGGGGATGCAGGTTGTCCAACACCTTCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGGGAGC
+
CH@AFF)BHI@G?BFDAG@??D@GGBIDAIG?FAIHCGEB$HB@?BG@BGDGGHHFGHGIICEH?D?FEFFDDGBHCBGAAFEGCF@@IADCECG>?FIB
@>chr21:9905183-9905346-5
CTCATACCACGCTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGTCCAGTAGCAAGGAGTCCTCCAGGAGAGC
+
@F@HAACFIHHAEI@@IAEIDHAH?GA@DEIIIGE@BHAHBCCC@@ADAFGI@GE@B?ACHCCC@IIDED@2AIAE@AA?DGE@CBGDDCDD?FHCH:+B
@>chr21:9905183-9905346-0
GAAGGTCCTCAGCTCCTTATGAGGCTGGGGTGGGCACAGCCTGGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGACTC
+
EEHAAE3C@IHDHD@CCGEAHCIDIAECGBFCEE?IBDC@#FCCE@FGBCAC?G@IIIG?@CDGAGBDHB@HI?CI@EBCDFA@DI@BDEAA?C?IHADD
@>chr21:9905183-9905346-1
GAAGGTCCTCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTCACNTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGACTC
+
@?ADBBHFGBHB?AAIH@?@?HEIAIG@CFIFEDGBGFHHF?DE?@@B@AC@DF'1GG?FHBFGHGCAAFCDA@DDI@GACG@ADGCHEFA@BBFIDEDA
@>chr21:9905183-9905346-2
GAAGGTCCTCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTNACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGACTC
+
?BDCC@HIFGGA@FADEFD?HIFC@@FACFHBF@FEIFFCICBF@FHEDIGC>DGIA@G?G?CBAHGCAEBAHDFIBFCGFFCBBBDGABGC@FBABBEI
@>chr21:9905183-9905346-3
GAAGGTCCTCTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAGCCA
+
I?IGBDH?CG@?HGIC@CG?IAGAFBDFIEFHBDFDBA?FHADAAA@E?CAABFCGHF@CB@IF@EEDHDHIDDFC@BC?IA@CCE@C@?HAADAHI@ED
@>chr21:9905183-9905346-4
GAAGGTCCTCTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAGCCA
+
BGDGIDFEI?B@IE?AHBGACIFE?CEG@FDG?BDFFG@H@B@G??A?EEIIC@?DFDGI@HFBB@?@GF@E@HIGICIAH@GD?CEBFFAADCIBEGDI
@>chr21:9905183-9905346-5
GAAGGTCCTCTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCNCCAGGAGAGCCA
+
ABBHEGIDGA?IDFIA@BBC?IIDBCEFFEIIHI?@BDIE@DE@HDDGC?CDEHFAAICHE@?CDHGIFG?A@CCDHI@D?HGBGEA#GAB4CDBG,EDE
@>chr21:9905183-9905346-0
GCGGCGTACAGCTCCTTCTGAGGCTTGGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGACTCC
+
?CCIHBDF@DBIADF?B?G?@CIAI:C@E@D@DCGFBCBFGHI??ICIDIH?H?B?ACCF?FDCGI?FG?HCCHBIEI@GIGFDH@?IEDIBD?@EH@@C
@>chr21:9905183-9905346-1
GCGGCGTACAGCTCCTTCTGAGGCTGNGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGACTCC
+
GGEGBDFC?CEIBGEAGF?CIGDCDF(GAAGHBHE@EG@B@EFGIGHF?BIED?AD?GDI@AHIBBFI@HB@DIFDH?@EGB?DA@G@GHC@GG?GEAD?
@>chr21:9905183-9905346-2
GCGGCGTACAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGACTCC
+
CCGBIAICCBCAB@@@@??GFCC?AGD?IIHEBF@A@C?AFACIA@?@FCCFFABACIBD??ECHBFGBIDGHAB@GCFCDBFHHF@@HBCI?EAAGIHI
@>chr21:9905183-9905346-3
GCGGCGTACTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGNCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAGCCAG
+
BID@?GFDDGEHC?CEBCEGIGGE@BCGG@IFGHAGFFFD@G?@BFI?DEBIGHE?EEDCIB;AADEFHGBDBBAH@CGI@DB?CGBIHBIFAEEFFDGD
@>chr21:9905183-9905346-4
GCGGCGTACTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAGCCAG
+
DH?ABIEBIDHDE@D?DHIBGAD?AD??E?FFIEBDG@DE@H@DAHB@?GDC?CEFCAG?AGHIBFDEE@IIB@FCHGD@E?HDGGC@H@FGDEBBIIG?
@>chr21:9905183-9905346-5
GCGGCGTACTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCGTCCAGGAGAGCCAG
+
ADI?AGBDAEI?IBFID?F?@CFFCIAE@DI?@IGHFEAEHDE??DEEDDD?DC@DBG@FHC@CDEIEI??GIBFAGDBC?DD@I#EFEI@BFDIEBAFH
@>chr21:9905183-9905346-0
TCAGCCGGTAATCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGA
+
IEE@&DDDDCFAIAFA?CFB@AC?EBIFDAACCC?DF@EBCEBACCHAFAHHGEFHC?CB?ECBB?FIAAECE?F?DDDBCDFHEFI@?FD@A?AAIDCC
@>chr21:9905183-9905346-1
TCAGACGGTAAACAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGGGCCTCACCTCCACCCACCTNCCATGGAGGTTCCTGGCTCTCCTGGAGGA
+
CGGF?HEBI?H3CEFDECB@HAIDFIIGBEGCA?DH;IHEICADBE@?DGBGDA??EA@A?EH@DGFIBF/FFBBGCADDBADEE?ACHBFCGBCFG@GB
@>chr21:9905183-9905346-2
TCAGACGGTAATCAGCTCCTTCTGAGGCTGGGGTGGGCACAGCGTGGAGGNGCCTCACCTCCACCCACCTCCCATGGAGGTTCCTGGCTCTCCTGGAGGA
+
IC@@@A@ACF?@BH@CGEIEGFH@A@EHGBFIFHI?CCB?C?IFBGD@FB1AFCD@IGECIFCHDFH?FE?HCB@E?IH?GDD@?FEHAD?@I@E8HEDD
@>chr21:9905183-9905346-3
TCAGACGGTAATCTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAG
+
IIHH?FGAIFFD@ECI?CACDF?D@??G??CCADFIHHCD@ECCC?D@DEAFBDCFF?FE@EDFAH?GCBHIEABGGB?@D@CBIGGEIIAB?F?@AFBE
@>chr21:9905183-9905346-4
TCAGACGGTAATCTGCAGGGGGATGCAGGCTGTCCAACACCATCCAGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAG
+
?DGCCDBEIAFEBCGGAGABFFIIHAAC?,IGHCGHICBFCFIEI2B@BGF?EHICIGFBD@ADGEF@CDHD@IEE?FBC@BCEGAGECBECCCHBDEGC
@>chr21:9905183-9905346-5
TCAGACGGAAATCTGCAGGGGGATGCAGGTTGTCCAACACCATCCTGGGACTGGTCAGCCCTGGTGCCTCAGCCCAGTAGCAAGGAGTCCTCCAGGAGAG
+
AAAICEEB(CIA@BBA@I@EHFEEIBBCBBAC?G@CC?BEACCGIIIE?BE@IDAGBF@DCG?C?GII?FDCFEI@FDGAFC?IEI?EEI@H?GHBF@HC
@>chr21:9907264-9907420-0
ATCACTATGTCTGCAGAAGGGTGTGGTAGCAAGTACAATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCTC
+
G#BHIBI?ABCIA@B@A@%DI@E'ECI@@DIIAD@C?DIDBFHGIABIIAFBHA@EHEEDAIIBIAAIHBDF8G@@GEDIG@?HEB@GHFICGGGBCICC
@>chr21:9907264-9907420-1
ACCACTAGGTCTGCAGAATGGTGGGGTAGCAAGTACAATGGGCCATGCACTTCTGGCGGACGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCTC
+
BIADHAI,DHAAF@BEEH@IIIH?I?CIAB?HICGCCCEHGGHDGABGEIF?BDHGABG7HDIHDDCFCH@A?FDFHH@CGHGBB?FEH@?F@EDGC?DB
@>chr21:9907264-9907420-2
ACCACTATGTCTGCAAAATGGTGGGGTAGCCAGTACAATGNGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCTC
+
IFC$IBID?HCE@D@%IBD?DD@?GBBGFB>AABG?IGAF#@CBAEDEB@@AADAEC@???AGDCCFDEA@HBIDIICEFAH??C@H@?I@CHHEEHBBE
@>chr21:9907264-9907420-3
ACCACTATGTCTGCGGGAGAAGCTTCTACAAGNTGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGTGAAGGACGTCCGTGCCATGACC
+
I?CAAGDFEDC?CD@IIBC@GBBADBAIBGB?=+DCAE@CIIHDFAAFAIGBD?D@EGHDBD?IHCIDBHICFCED?-@HEGI?CG@D:%EGEBGCGAEE
@>chr21:9907264-9907420-4
ACCACTATGTCTGCGGGAGAAGCTTCTACAAGCGGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTTCCATGACC
+
E@IIGAB@???EGEA?AC@EICCEBHBHEBDAHAD@HGB@ED?FIADDHCABBFA?HFD@IGG?G@BD?E@HDIG?@A?DIA?EGCC@B@I:CFE?C@AG
@>chr21:9907264-9907420-5
ACCACTATGTATGCGGGAGAAGCTTCTACAAGCGGAGCAGTCTNTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGACC
+
?DFGA?CDGC1IBEGCGIHCGGA??A@EIEDGCECHIAAIHG+%D@AEFICDF@GD@GIHAE?B@FB?GHD@A?FBDE@FDEEGB@@@CFIGFH?@?CBI
@>chr21:9907264-9907420-0
CTCATACCACGCTGCAGAATGGAGGGGTAGCAAGTACAATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCT
+
EBD?H?DIHDGGE?CB@DHIG@<?IHCHAG?DF@ABICFAB?BIG@HB?CBA@FFIEDEBCDD??DIAFEEGDCEFHCB@H@@?CEAAADHA@??IBHF?
@>chr21:9907264-9907420-1
CTCATACAACGCTGCAGAATGGTGGGGTAGCAAGTACGATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCT
+
EFI@HAD=D?BFIEACH?CDFCAEACG?I?CFACEFDFBDGD?GHE@H@CGAI?CAGCE@EEEAF?BIEADBEII?CAIFFFBHAHEIBC?IFDG?BBHD
@>chr21:9907264-9907420-2
CTCATACNACGCTNCAGAATGGTGGGGTAGCAAGCACGATGGGCCATGCACTTCAGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCT
+
?FCDFAG>?G@BB3??CGA?@G@AABFI@DI@GA%HHDEBBEGD?BE@AA@IGE+D@D?GAGICDIG@@GB??FGFFA@CDGBGIDAICBCBCAIHE?HD
@>chr21:9907264-9907420-3
CTCATACCACGCTGCGGGAGAAGCTCCTACAAGCGGAGCAGTCCCTGCGCAACCTTAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGAC
+
GICFHGFI?ABGEEEECE@?@E@HD!?FBCF@GEACHGHHIH?C@@G?IFADCHC3AHCB@E@@ICDDDHCE?B?BDECD?DDHBFIBB@CD?EIECDBE
@>chr21:9907264-9907420-4
CTCATACCGCGCTGCGGGAGAAGCTTCTATAAGCGGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGNCACTGCCATGAC
+
HG@BADIE-DCB?G?HA?GDCFAFBCC@B%??IGBIFHA@?EFEA@BEG?DF?H@GAHDCEDFIBECIAE?C@@?BI?IF?EGGFDA0G@AICIC@CBDI
@>chr21:9907264-9907420-5
CTCATACCACGCTGCGGGAGAAGCTTCTACAAGCGGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGGAGGGCGTCACTGCCATGAC
+
GIFHHGCH@@DGGIGGHHG@EE@BAAGGF?DEIF?FEHB?GEA@IDCFE?EIIEC@BGHDAAEEA?GID@@DHBIIAEDI&EGD"D@BEGFFEA@DCI?@
@>chr21:9907264-9907420-0
GAAGGTCCTCTGCAGAATGGTGGGGTAGCAAGTACAATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCGTGGCAGTGACGTNCTTCTCC
+
IDDI@AAIDDC?EGDDED@EEHF?AFDDEEBDFA@CHHBIBBDFB?H@GB@D?F@IEADB?H@CGF?FCEDAIICAD@B6DFEIEIFEGDCB<C?B@GCB
@>chr21:9907264-9907420-1
GAAGGTCGTCGGTAGAATGGTGGGGTAGCAAGTACGATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACTTCCTTCTCC
+
HFIA@@F>II&?4ECI@FIBFBAH@GCF?C?GBBADBHDDF@GB@IEID@D?FGBGF?@?BCHEB@FEHIABF?D?HFAHEF?EA@II@F0A?EFEIHBF
@>chr21:9907264-9907420-2
GAAGGTCCTCTGCAGATTGGTGGGGTAGCAAGTACGATGGGCCATGCACCTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCTCC
+
@ACFCF@EEG?I??BG&E?FCIIDF@@@?GFHEGDHICCGE@IAE?CBI+?CHAAIFD@@EB@F?ABEFA?AAHA@IGBCHACE?DBCB@CACDDADECF
@>chr21:9907264-9907420-3
GAAGGTCCTCTGCGGGTGAAGCTTCTACAAGCAGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGACCA
+
A?EG?F?DDE@CGFIE*A?CCGEFDDBF?CCG5@@HEEGGDIGIIBBG@?ABHBAGDA??EIBBBCHAEGHHH?AHFIB@@?HEIIGH@DFC@IH?HBD@
@>chr21:9907264-9907420-4
GAAGGTCCTCTGCGGGAGAAGCTTCTACNAGCGGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGACCA
+
@ID@BAHII??EHBIDGAED?EHCDDAE;GA?CBGDEIF@EFCC@EIHE@GA?HDFGEEFBC?FC?GAEH?BBCECBACHCB@IFGFFDGBCECII@@AE
@>chr21:9907264-9907420-5
GAAGGTCCTCTGCGGGAGAAACTTCTACAAGCGGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGACCA
+
ABBHHBDG?@GCGACFI@@E-F@GDHFBAF?HHH@DBHCG@CH&FHBAHEEHDAC?GAH?G@GDBIAFDGHCAIHDFIIBFAAE@HI@DEBHAEAF??B@
@>chr21:9907264-9907420-0
GCGGCGTACTGCAGAATGGTGGGGTAGCAAGCACGATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATCGCAGTCACGCCCTTCTCCA
+
BGFHDIFGDBDFCBBDCG@BH?BFD@C?FCI5IFICI?I?G@IG@EDACEIF?GDFGFF@@FDB@I?I?BBCD?CBAGH@8?AIEC2CBE*DAI@DBAFG
@>chr21:9907264-9907420-1
GGGGCGTACTGCAGAATGGTGGGGTAGCAAGTACGATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCTCCA
+
?)FIIEDCEDAHCDBFD?IG?H@IDEAGBIBGBBACGI@EGHEEIEBCDIAHFBCEGF?I@?@D@C@FDDA@ACIHHB?GEEBCB?@CGD@H?AF@AH@?
@>chr21:9907264-9907420-2
GCGGCGTTCTGCAGAATGGTGGGGTAGCAAGTGCGATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTCTCCA
+
CGHHHG@)CDE@BIDHFBBI?G@III?HHBDF%BD?HAHG@@A@?GBIIBCF?GBBFGEIIDIBADFCD?GFCIG@G@DI@@AG@IHGGDE?AAC@C?FA
@>chr21:9907264-9907420-3
GCGGCGTACTGCGGGAGAAGGTTCTACAAGCGGAGCNGTCCCTGCGCAACCTCANGGACATCCACGTGAGCCTGGAGAAGGACGTCACTGCCATGACCAA
+
CA@DBDFEAIC???@FGHGI2D@G@?@@HHE??CFH1B?CEIIHEBFDB?G@BF#IF?DIEGAB?(ADF@?GHI@ICBD@H@HB@@FCABEDGDEHBICF
@>chr21:9907264-9907420-4
GTGGCGTACTGCGGGAGAAGCTTCTACAAGCGGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAAGACGTCACTGCNATAACCAA
+
A*@ADBEGAC?C@?BB?EICAECCCBI@HGD@?DAFC?DG?@@EFBDHDH?D@HE?IB@@@EGGG@HHFBG?IAFHIFD5BIBIEDF?GAI6?F$GEAH?
@>chr21:9907264-9907420-5
GCGACGTACTGCGGGAGAAGCGTCTACAAGCGGAGCATTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGACCAN
+
GGA&HCGAIDBHEDB@EFFGA/EGFEHDHACFDDCCB$BDDDDBBABFAB@IECGBEGBI?ECFF@CEBD?DH?I?G?CCD?GGEIC@@@EIBCIH?EG6
@>chr21:9907264-9907420-0
TCAGACGGTAATCTGCAGAATGGTGGGGTAGCAAGTACAATGGGCCATGCACTTCTGGCGGTCGATGAAGATACTGTTGGTCATGGTAGTGACGTCCTTT
+
@?BIHAAD?@CFBC?HBHIDBBDA?FAGEGI@HIE?@@FBGBIGBAE?GFI@AHCEDDCBCAEI?AFBA?A/I@F@CHDBGHAHCH#IDEDFH?EF?GH0
@>chr21:9907264-9907420-1
TCAGACGGTAATCTGCAGAATGGTGGGGTAGCAAGTACGATGGGCCATGAACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACNTCCTTC
+
@IBBDB@BFC?@IBDBBHIHEGBC?CGFHHIC?DD?@DIGE?DEEB@AA"DEEGCI?DBGII?DBE?IAE@@?@HABIB@ACCGC?HD?I@EF+@?BHGH
@>chr21:9907264-9907420-2
TCAGACGGTAATCTGCAGAATGGTGGGGTAGCAAGTACGATGGGCCATGCACTTCTGGCGGTCGATGAAGAGACTGTTGGTCATGGCAGTGACGTCCTTC
+
FBDBGDDH?FABFADIDA@CIG?@ADADACCD?FB@H@AAFFC@GFCFDIBBAEFD?@AIEDAFIGBBDGBBIBFIC?ABIEDFAACDDHGCCEHCDGHG
@>chr21:9907264-9907420-3
TCAGACGGTAATCTGCGGGAGAAGCTTCTACAAGCGGAGCAGTCCCTGCGCAACCTCAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGA
+
C?A?HIBECFFEFHDDIFAF@CE?BCDFIEID@ADH??FFDICIBFDHCAAGFACIGHHHHCE@?AB?EIBI@FEEBF?@D?G?BHGGECDIII@HCIB@
@>chr21:9907264-9907420-4
TCAGACGGTAATCTGCGGGAGAAGCTTCTACAAGCGGACCAGTCCCTGCGCAACCTCAAGGACATCCACAGGAGCCTGGAGAAGGAAGTCACTGCCATGA
+
IEF@HAFEA?EAAA?HD@IHA@IHII@B@DIHBDG?DG+GI?HA?BEIC@EDHB@C?GBCBCAGC@BHAH+@AA???BHEHBEDFH+BBDGGDFE@HI??
@>chr21:9907264-9907420-5
TCAGACGGTAATCTGCGGGAGAAGCTTCTACAAGCGGAGCAGTCCCTGCGCAACCACAAGGACATCCACATGAGCCTGGAGAAGGACGTCACTGCCATGA
+
ADBDCDIDHH@AF?FCFBGDA@HC@?E@GE@ECAI@AAIB?DG@IA?I@@CHGGB7CHIGFDG?HEGDCAEF@BI?FC?DHHD@CFCFEAGH@AEIHEHE
@>chr21:9908223-9908290-0
ACCACTATGTCAGCGAGGAGGTGGATGGGGANACCTGGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGACCGGAAGAGCGAAAAAAAAA
+
AHDFICADE?DDHHFAGGEB@IEA@G@CE@A3FE?DHDBAHAAEFC?CHGCIHHGBFBEDEICGDGHEEI@EHGAAIHC@1EIEHGGCHGEC@HE?AAG!
@>chr21:9908223-9908290-1
ACCACTATGTCAGCGAGGAGGTGGATGGGGACACCTGGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAAAA
+
DE@E-F@F?FDGA@IIFHGHB?AABAH?EGBBAAHIDD?BCICBDAEH@A@C?@EBDCCAEFIABGFH?IHBH@E@@?HBH@FGEIHBCDII??@IBIHG
@>chr21:9908223-9908290-2
ACCACTATGTCAGCGAGAAGGTGGATGGGGACACCTGGGACTGCCTCAGAGCCCCAGGCAGTACCTGAACTGGGNTGAGATCGGAAGAGCGAAAAAAAAA
+
F@EDAAABA1HHAHGF@&IBH@IFCEAE@FFHBHBFE??IHDGIGBIAAEG+E??ADAFECDA@EIE?GFA?AB0CEHHI?GDG?BFEF@E@?FACG@AC
@>chr21:9908223-9908290-3
ACCACTATGTCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGTCCCCATGCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAAAA
+
CCEGGFDCFIHEDI@AGBAHCAAIE@GGGHCGABII?@B?DG@??(HB@IGBECI?@GAFGGA-DADGCI??IGGDADHI@EGG?DG?GBEE@??AHHGI
@>chr21:9908223-9908290-4
ACCACTATCTCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGTCCCCATCCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAAAA
+
CFICBAFH9BBDA@I@I?IDIFE?ADGHGBFC@@CGCEH?IDBHADBACCBDHFDIEED@A@HIB?AG?AHABEGGD:F@AAB@DBAHDADHGH@IIAFD
@>chr21:9908223-9908290-5
ACCACTATGTCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGTCCCCATCCACCTCCTCGCTGAGATNGGAAGAGCGAAAAAAAAA
+
IE?EDE??AAFDIH@B@?EIBBAD?AA?@CHBIF?AF?A@@C@?CIBGBCC@GAHDA?FB@?CFFGBHAAI?BDH??EDAC*H?ACHIC?AHDD?ABGBG
@>chr21:9908223-9908290-0
CTCATACCACGCAGCGAGGAGGTGGATGGGGGCACCTGGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAAA
+
BCID@EFD?AHABIIH@?BD?DAFAGBE?FHBAHEID?EA@IFABDDI@HACAECHEGICEADECB@@DDHDGBGH???HCFIFEADCEA?B?H@HEI??
@>chr21:9908223-9908290-1
CTCATACCACGCAGCGAGGAGGTGGATGGGGGCACCTGGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAAA
+
FG?IICIAIBBEDDCDBFBIAAIEDAGAC?HCABABHHDCIDIIEGB@?IDI?A?CIGCDACAGGB@IDBDA?B@DFGBIG?ED6D?ABIB?A?@D@GIH
@>chr21:9908223-9908290-2
CTCATACCACGCAGCGAGGAGGTGGATGGGGGCACCTGGGACTGCCTCAGAGGCCCAGGCAGTACATGAACTGGGCTGAGATCGGAGGAGCGAAAAAAAA
+
CDIAIB@AI@BCI@FDIABC@@CEAIF@D?@GB?EFA@FH@AFAE?EG@G?EAACGGEGDICHIA;C@ADFI@FEIBAG?GGEHHG+??DG?DBEADC?F
@>chr21:9908223-9908290-3
CTCATACCACGCAGCCCAGTTCAGGTACTGCCTGGGCCTGTGAGGCAGTCCCAGGTGCCCCCATCCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAAA
+
DGDFHGEBDHHI@FF?BCHBA?FD@E?I@IF@DEAF@G?,BB?H?GFGBE?E?GGAHEGDC@BIA?D@ACBAIG@DGDFFAF?CFE@D@@ICB?CGHFB?
@>chr21:9908223-9908290-4
CTCATACCACGCAGCCCAGTTCAGGTACTGCCTGCGCCTCTGAGGCAGTCCCAGGTGCCCCCATCCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAAA
+
GHCBBH@??D?IDHBBCAFGB??F@GDC?IDGB?=HDAGEFGHDB@@G@DFBB@FGCI?FIBCICD?AB@GIFCD?DBBADC@B@BAG@EA?IHB?H?@?
@>chr21:9908223-9908290-5
CTCANACCACGCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGCCCCCATCCACCTCCTCGCTGCGATCGGAAGAGCGAAAAAAAA
+
AHDF+BF?A@FIECIEA?BBACG@?G@DADDGACGBHFEBEGHBF?CAA@ABCHAIID?@GBAFHFH@?CI?GDAGDG/@@CDD?@IGFF?ID?FBI@FB
@>chr21:9908223-9908290-0
GGAGGTCCTCAGCGAGGAGGTGGATGGGAACACCTGGGACTGCCGTAGAGGACCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
A*?H?B?DEH@?@FFDGI?B@GDHCDFB4HDCAGEIAACGHBCC>7@CIDA-AFADCHAE?C?D@II@ABG@GFFHIHGGIAD?GIA?F@AEHGFB@@IC
@>chr21:9908223-9908290-1
GAAGGTCTTCAGCGAGGAGGTGGATGGTGACACCTGGGAATGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
DHCBFGC/AC@FEF?B@H?DBFFHAHG2IHFC@EACAG?1FHHGB@I?HBGHHC?AICH@DCGI?D?GE@D?EGGEBECFEB?@G?IGI?EA?FIH?GAB
@>chr21:9908223-9908290-2
GAAGGTCCTCAGCGAGGAGGTGGATGGGGACACCTGGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
A?C@IFDCEGIDCCA?G?CIA@?EI@GEIBAB@CGGACHC?EH?BG?EBH?EEF@BCBAHB@IGDBFBI@@?@AFGAAIIAAD@HHHBAHAI@FBH?C@H
@>chr21:9908223-9908290-3
GAAGGTCCTCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGCCCCCATCCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
AD@?@?C?CIHCGIFBF?FDHEHFDBDCDGFBH@BBBA@??CF@@HIBFH9EEGD$AH@E@FDAAHFFIDA?IG@?F?@GFDD@?FIIDIIFEG?DIIIG
@>chr21:9908223-9908290-4
GAAGGTCCTCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGTCCCCATCCCCCTCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAA
+
IF@GEC@F@EFFBFGAI?BGHFEB@GDE@IBHHHI?FABDA?FCCGCBFEDFDIHFIGEIHFGE+BIHAG@AGBAIA?@H?DHFG?HGHE??GIHDHAFH
@>chr21:9908223-9908290-5
GAAGGTCCTCGGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGACAGTCCCAGGTGTCCCCATCCACCTCCTCGCTGACATCGGAAGAGCGAAAAAAAAAA
+
DFA?GFHDFC2DFFBG@HBEEH?@IBBBHGEDDHFCCEFIC?(IGAB?FGA@IDD@I?CDCAFDI@GFEGHGBBC?F5AA?GB@C@AIFDD?6CCCGG?@
@>chr21:9908223-9908290-0
GCGGCGTACACCGAGGAGGTGGATGGGGACACCTGGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGGGCGAAAAAAAAGNA
+
CBIAEG?I?A>FGEDIF??CIIECEBHCFFFEEDGD@FFAFCEFHEEBBHHGA?A;HAAHD?EIBAEG?D?B@DCIF@G@ICHDE0ACDGAGE@FGB1!G
@>chr21:9908223-9908290-1
GCGGCGTACAGCGAGGAGGTGGATGGGGACACCTGGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAGGAGCGAAAAAAAAAAA
+
BCBG@GF?DGHF?FD?C@@H@ECBHFIHBI?BEABCDBGFCCBEGCEEAII@GE@BHFA@AB@FIIFCA@DCFCIDIDBGADB"F@CFEF?AAA@ABHH?
@>chr21:9908223-9908290-2
GCGGCGTACAGCGAGGTGGTGGATGGGGACACCTGGNACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGATNAGCGAAAAAAAAAAA
+
FCEBFCCFHF@GHEHH*FAEI?C?BB0BDAEBHBDD&?IGDCC@C$GGIAFHGE@HCBE@?AHBAGIDHCDB@AGDC@ICCB@";G@CDG!B?@HDE?@H
@>chr21:9908223-9908290-3
GCGGCGTACAGCCCAGTCCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGTCCCCATCCACCTCCTCGCTGAGATCGGAAAAGCGAAAAGAAAAAA
+
BAAAHHGCDADDAGG@B:AF@CBGADBF???GD@@@?HC?AGHDFGHGCH?ABEEF?BIABCGFDDHBHGB@?FBAGAF@@FHI4EI@IID@A*BBDGAH
@>chr21:9908223-9908290-4
GCGGCGCACAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGTCCCCATCCACCTCCTCGCTGAGNTCGGAAGAGCGAAAAAAAAAAA
+
G@?GCG,EIHDBGID@?AC@ABBGD@BCCEFBHG?GDD@GIIBAABIIACIEDHCEE3DIAEBGF?EHACDEGGI?H-HGECIE?EHGEDAHD@GIBB@E
@>chr21:9908223-9908290-5
GCGGCGTACAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGTCCCCATCCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAAAAAA
+
ECCCAH?DGEHEBCG@FB@FG??CBFBEGDFCIIIAFFCFBBDBGDECF?DDAGBEICF@EHG@D@CAEAHG?C?FIHIEHACEEBHCEAGB@C@D?EAH
@>chr21:9908223-9908290-0
TCAGACGGTAATCAGCGAGGAGGTGGATGGGGGCACCTAGGACTGCCTCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATGGGAAGAGCGAAAAAAA
+
G?AAIAGFFIICF@A@GIGFIHHIEB@FG?@G?HICCF/ID??IH-@DFBHGIBAIIC@/BBIGFCHCA?HBDCHEHF@H?E?:??C@@?@BFF@GIFAD
@>chr21:9908223-9908290-1
TCAGACGGTAATCAGCGAGGAGGTGGATGGGGGCACCTGGGACTCCATCAGAGGCCCAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAA
+
HBBEFCDIHEHCDIHCGGI@H?DAABIH?CBD??FE?IAGFHDC8?2GDHBBCIFFIIG?BD?IGF?IDDHB@H?EC@CHEHFEIHBIHEEEIEI@DIAE
@>chr21:9908223-9908290-2
TCAGACGGTAATCAGCGAGGAGGTGGATGGGGGCACCTGGGACTGCCTCAGAGGCCGAGGCAGTACCTGAACTGGGCTGAGATCGGAAGAGCGAAAAAAA
+
@D@ABIDB@FG?BGABBFGFIBDGF@?CCIHACDAIFBEAA+HCEGAH?HIC@B?I<DAGI@DIBEA?@B?ACACIEGBEDDHIH@BC@EFDBBDBIA?C
@>chr21:9908223-9908290-3
TCAGACGGTAATCAGCCCAGATCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGCCCCCATCCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAA
+
BCBCIG@EIAAAEFFAGE@B5HE@IAEDFIFBF?IBDBCG?@GAAA??IABFCA@HFGHBAFIFGBAD@DCHIGHACG@FCIDAABDEIDFBCBDF@CD?
@>chr21:9908223-9908290-4
TCAGACGGGAATCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGCCCNCATCCACCTCCTCGCTGAGAGCGGANGAGCGAAAAAAA
+
CCE@FBA@)?DACIFFGGAICCFB?ABIIG?BEDBAEGBBAFFGFBGDAIDGA?BAI@GC@6HDAEBABE@EAH@FEGEF@B!IC??1@GIA?BDAEHGG
@>chr21:9908223-9908290-5
TCAGACGGTAATCAGCCCAGTTCAGGTACTGCCTGGGCCTCTGAGGCAGTCCCAGGTGCCCCCATCCACCTCCTCGCTGAGATCGGAAGAGCGAAAAAAA
+
HCI@CBBE@@@BC@H@?HHBEBBCIADFHGBEF???HIECB?EHE@?GI@HGAFE?FDHIFDFCEE@FDI?BIDCEADHFDFBHDC?ABB@H?@H@?@IF
@>chr21:9908303-9908429-0
TCCACTATGTCTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGTGC
+
!EF@AHBDCHG?CCBDADI@E?HGBFHBCG@?E@CEAADGGDCABBGEC@?@GBGHCG@@@BBCI@HG?EBGGI?ACGB?GGH(FGHGDCCG?IEDIDEB
@>chr21:9908303-9908429-1
ACCACTACGTGTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGNGC
+
?C@BIHF<D@7FI@ED??HGD@F?HHH@IBFHHCEBGEIFED?IFFBBGHH?GCCAAIBCFCCGD@AAFFCHDHDHIIG@DCFII@GFDBHAF@CBB#HC
@>chr21:9908303-9908429-2
ACCTCTATGTCTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATCGCCTCCTTCAGTGC
+
AHI-BEHC?CEFDFEHEHIFGAIFCCDCCDC?BDE@AEHH@F@HEI?BAICI?DBDFEA?HG@HG@IFDDABG?FEECHEFFDFC*BDC?@DH@FGFCG?
@>chr21:9908303-9908429-3
ACCACTATGTCTGCGGGAAATCACAGATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCNGCACATTGCCCAGACC
+
AHF@EBEDGIED?@@'HHIEF?FFDB@AB?CAHAEBBIHBEEIAI/AAID@GCGHF@H@B@@AEC@IAFEDFEFG@G@?I-AB1F??@BF6H?BE?BBIC
@>chr21:9908303-9908429-4
ACCACTATGTCTGCGGGAAATCACAGATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGACC
+
BGH@D?@A)CBEEDEEA@FEEHIF?HDBBEFCADCF@@HCIIHIFGIB?IG?GCGE@EBDGHGC?I@DAI?IHIDF?@AIDDAGDCADBECF@BDEH?F?
@>chr21:9908303-9908429-5
ACCACTATGTCTGCGGGAAATCACAGATCAGGAACACAATGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGACC
+
C@GBCEG?@ADDH?@BFGADIDIF?BDHH?DAFDA@BHB"GC?BBFIDAF@II@DEGCIDFFADB@FFFBA@E@@8A@EHEB?EDDC?FA@@(DA?BHCI
@>chr21:9908303-9908429-0
CTCATACCACGCTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGTG
+
H@B@IDBFDHCDB@?AGAFCEBDEACIHF@BFGHDFDHG?IC@?CHFAHI?B@I?CEIEIB@BGGHI@GGAHFE?DAA?@I@@@FH?BACFGDGFCHHIE
@>chr21:9908303-9908429-1
CTCATACCACGCTGCATGTTGGGCCGGTGTGAGAGCTACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGTG
+
ADF@HF@@?CGBIHF?@@CDBCEBIHBI@I@BF@AI&F@EF?DE@AGHBFHBBAFF?CDD??BGD?HFA?CFFA@@CGCH?CBFBDEE?BBBFHGHFDID
@>chr21:9908303-9908429-2
CTCATACCACGCTGCATGTTGGGCCGGTGTAAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCCCCTTCAGTG
+
?FFEDBC?FCE?FDAHFABHIFDEHCCIH?7I@GCBEFBIF?IFH@AF?DIHCE?FD?I?BC?GH@?@GE@BGDDF?HA?F?GFF?A@A@&CG@GFIAFG
@>chr21:9908303-9908429-3
CTCATACCACGCTGCGGGAAATCACAGATCAGGAACACAAAGTGGGGGCACTGCAGGAGGCCATCCAGGACAAGGAGGAACCTCTGCACATGGCCCAGAC
+
EEDGIA?BDF@HD?GCGDFAG?HEIHFGGB??A@BAD@HC,D???1F@A@ICA-?@EDDHCEDFE9C@?H?E?G@@C?DDEB??A?>@BB?2CHGGFIEG
@>chr21:9908303-9908429-4
CTCATACAACGCTGCGGGAAATCACAGATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGGGGAACCTCTGCACATAGCCCAGAC
+
IGFAH?B'A@BF?CHDFEFFGD@GFEEECGBI?DAE@CE@AE@EBAE@F@HHHFE@AGAIEGC@A@FEBB?EFE@/F??DDFECFA?ECF?GG@H?E?CI
@>chr21:9908303-9908429-5
CTCATACCACGCTGCGGGAAATCACAGATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGAC
+
FAA@BFDED@C@BF@@H?ACADIBEEA@?I?@FGG?EBHDD@HAB@IBFFDFD@IFFDHIBACBIH?@CEE?F?FEB@F?A?CB@HIEDGBAFICHA@GC
@>chr21:9908303-9908429-0
GAAGGTCCTCTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGATATGTGCCGAGGTTCCTCCTTGTCCTTGATGGTCTCCTTCAGTGCC
+
G?AA?CFGHFFGACCFGAIHI?IF?EIHIEA@I?GG@@GCI?IHFCBHB@IB?.ED?EHDB"ABECF?B?H?AGADD?DCA?A@@?'BFIGIGAIGH?HH
@>chr21:9908303-9908429-1
GAAGGTCCTCTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGTGCC
+
EHCCC@HIIICG?I?DABIDIA?AG@FH?CA?@DHCFA?@DHIHH?C"IGEAHGFDF@AHDGBFGH@CEIHFHI?CEHDD?GBAFGFD?EHG?IGGICCB
@>chr21:9908303-9908429-2
GAAGGTCCTCTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGATGTTCATCCTTGTCCTTGATGGCCTCCTTCAGTGCC
+
IBIFGB?DBAC@DFACEGH@EDE?IBG?BGCFFE??EAD?CHAF?@A1?CBCBCEAICA@GAID!GC?H6@ECHEAGEEDGF@BFBH@GAEEHFHDEIF?
@>chr21:9908303-9908429-3
GAAGGTCCCCTGCGGGAAATCACAGATCAGGAACACAACGTGGTGGCACTTAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGACCC
+
C@AGFG@F:HB@E@EIFIDCBHD?A?CCCHGIHF?I?DEFFIAB@IDBHH%CAHDIBCI?D@IG@B@ADHHBAHCHG@?BFABHGA?E?@IIFGICD?FF
@>chr21:9908303-9908429-4
GAAGGTCCTCTGCGGGAAATCATAGATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGACCC
+
HH@@FI@AABEC@?BIIADAEB'CIAHID?HBDAHAGFFF@FII???IB?GEEB@DDABBAG?CGAHBAGD@CB@FIFCFDFDGE?DFB@G@@D@DCFI@
@>chr21:9908303-9908429-5
GAAGGTCCGCTGCGGGAAATCNCAGATCAGGAACAAAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGACCC
+
CCBDIFCG9GFBCFBH@FD@D-EAAAGGGFGBEHI,EFE?EGC@@@FBG@?FIGEF?AFF?DHIBACAEIC?EHG@@??AF?IFCHACDDI@IAIFBIA?
@>chr21:9908303-9908429-0
GCGGCGTACTGCATGTTGGGCCGGTGTCAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGTGCCA
+
H@EFGGDDIAB@GIIHDICBBBBDEB?7?DBB?@FBECFI@HHGEADADEIF?CFHIGIIG?HFGD@HAFFIG?CI@H@DDACGD??FA?BBDFHD@ICD
@>chr21:9908303-9908429-1
GCGGCCTACTGCATGTTGGGCCGGTGTGAGAGNAACTACAGCCGGGTCTGGGCNATGTGCAGAGGTTCCTCCTTGTCCTTGAAGGCCTCCTTCAGTGCCA
+
CEBAD;G@GF?BDFB?FEBDBHCDEDAD?IHI3@DCC?EIC@D@ADFCGEEG?=IFCBD@EHAHCFICA?DFGAA@?ADD@G$IDBBG?BEFB?AEHEAD
@>chr21:9908303-9908429-2
GCGGCGTACTGCATGTTGGGCCGGTGTGAGAGCAACTACAGCCGGGTCTGGGGTATGTGCAAAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGTGCCA
+
EB?FGFHCGEH?@HEEAD?EFFHIICIFBD???FAEIDCEEGE@IBGBDBBE<FIID?@DE+@@G?EGFAEDCF?EFHHH??GDGHCA?F@EE?FDBGII
@>chr21:9908303-9908429-3
GCGGCGTACTGCGGGAAATCACAGNTCAGGAACACAACGTGGTGGCACTGAAGGAGGCCAACAAGGACAAGGAGGGACCTCTGCACATAGCCCAGACCCG
+
@DHFGD@E?HIF?HHIGDIDGCDF1BGAAGAAE?HABH@?@HFEA@@@BI?IIG@BG@FC<@EBA@IHHFE?CHB9ICBDAAHHE@@@AEHFC?BC?IHH
@>chr21:9908303-9908429-4
GCGGCGTACTGCGGGAAATCACAGATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGACCCG
+
@H@EG?B*H?@GACII@HGGBBBACIHHG@?BHEC@B?@FAEB@H@EFFH@GGEB?AAHGDH?GGAHBDGE@CB?GGD@EABCFEIFFFFCD@?I@D?@I
@>chr21:9908303-9908429-5
GCGGCNTACTGCGGGAAATCACAGATCAGGAACACAANGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGACNCG
+
IAH?F4A@FBAHBGE?CIEI?ICCIHFDHDGDIGIGB5C?B@IC@EFIA@G@@H?FIEBEHFBCICIH?ABCI?AFD@GG?BAGDCE@AGFEG?DDA5@F
@>chr21:9908303-9908429-0
TCAGACGGTAATCTGCATGTTGGGCCGGTGTGAGAGCAACTCTAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTTCTTGTCCTTGATGGCCTCCTTCAGT
+
FGHCD?CG??CHIFACBDDFHA?CFHACIIFCG@HDHIDECE%HCDAIIEDI?@B@CE@CDGFAGHHHI?H@?F/HE?EGHEEDD?AIIIACB?DD@C@E
@>chr21:9908303-9908429-1
TCAGACGGTAATCTGCATGTTGGGCCGGNGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGT
+
DIHDGEF?IA?C?HCFABDIBEEDFB@?#HFB@DDGBDFFE?GCD@GDCBH??D@H?DABE@CF?GH@B@AIIFBH@@@HHEIBHBI@@?AIFHGFCDDE
@>chr21:9908303-9908429-2
TCAGACGGTAATCTGCATGTTGGGCCGGTGTGAGAGCAACTCCAGCCGGGTCTGGGCTATGTGCAGAGGTTCCTCCTTGTCCTTGATGGCCTCCTTCAGT
+
HCBHBHE??B?F@CCIIIEAI?FEFHGF?@FGAIHGCDA?G@@H@EGGACFECDACAABFG@BGCFGDHAFAF?EDDDB?F@GCH?GEAD@?AA@GEAIE
@>chr21:9908303-9908429-3
TCAGACGGTAATCTGCGGGAAATCACANATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGA
+
EEAB?CBBEHFHHBFGCD@BAF?C?GD*BDGGDCFCHEFI??IFGIFB@AEA@CBADHEIFICDHGHHFAIIH?CE@B?EA?IGBGE@HDHC@E?C?FDC
@>chr21:9908303-9908429-4
TCAGACGGTAATCTGCGGGAAATCACNGATCAGGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACCTCTGCACATAGCCCAGA
+
ED@ADIBIBBCI?F@HH?>DDGD@DD#EEGDBD@IBG?CH?FACBDFB?GEAGDB?BFCBGHABBDFGGDGI?GF@@IFDEEAIBIBIDCDEFDDH?DGD
@>chr21:9908303-9908429-5
TCAGACGGTAATCTGCGGGAAATCACAGATCANGAACACAACGTGGTGGCACTGAAGGAGGCCATCAAGGACAAGGAGGAACNTCTGCACATAGCCCAGA
+
FADG?EFBAAD@CBFDICIGF?FC?@IHABEF9DHGGIIHAHGDG?AHECBBFEHDBHEICIHHBFAA?H@CHFBHAH@HF@:HDEGG?FGBECABDIC@
@>chr21:9908426-9908622-0
ACCACTATGTCAGCATCTGCAGACAGGACAGTGCCCATTGGGACTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGCT
+
AIHCECCEIBFIFFG@GFEBA?EGDAA@DC@CH@AC1BCFFIID@EFEFFACBFBDDBBB?FGFBF@HCI?IAEFDCGECEGBI?EDBAGI?DDCIE@@?
@>chr21:9908426-9908622-1
ACCACTATGTCAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTGTGCCCCCATGCCCGGTCATATGGAATGTGGAGACCAGTCTGGTCCTACCCAGCT
+
HDBDDBHBFDD?CI?IGBABBEAH@HABIGIG?CE@FHBG?@@CHAHAHDFF?FEA@?EE?,D?HFAGC@GE?E*IGAAEACGFHEBEBCIH?IFDEFBD
@>chr21:9908426-9908622-2
ACCACTATGTCAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTGTGCCCCCATGCCCGNGCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGCT
+
E?BFIDFHE@H?@IFHC?GCA@B?ICDABII@?ABGACDCCIDEAH?CGGH@AH@GHEC@0@ADGIEF@GEFII?IGBE?HFIHHGIA@FAFGCEFDH@@
@>chr21:9908426-9908622-3
ACCACTATTTCTGCCTGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCACGGCTCCCCAGGGCCACTGGTCAGGACCACCCTC
+
IG@BC?FI3GIHI@DCE@GFAIGADGBD?F@GICFF?I?GDAF?GF?BBBFDE@HE?@EA@I?DIE?I2IBGHCEEABHIH@EB?EHAADEGFAFGIHEB
@>chr21:9908426-9908622-4
ACCACTATGTCTGCCTGACTCTCCAGAGGCCGCTGGGGGCCCCGTGCACATTGTTGCCCCCACCCAGGGCTCCCCAGGGCCACTGGTCANGACCACCCTC
+
BEFDIGBHDDGHBAF@HFCD@CHA?IGC3EABEGEIGHBABF@H@@AIB?CC??B4CII-?EH@FE>A%I?FFHE@CG?G?AFI?IAFB"E?ECGDC?DD
@>chr21:9908426-9908622-5
ACCACTATGTCTGCCTGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCNCGCCTCCCCAGGGCCACTGGTCAGGCCCACCCTC
+
F?E@BBGAAIDBIAFBHGFIGFBDCF?FGHF@DGHBFD?FGICDGG@I??FF@@CF@;CGABF@H)@HGG???ED?BAD@@BIDGEC?FDG3?FDEE?GG
@>chr21:9908426-9908622-0
CTCATACCACGCAGCATCTGCAGACAGGACAGTGCCCCTTGGGACTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGACCTGTCTGGTCCTACCCAGC
+
BGCCIGGFGCGB@EHCGI%FEGEICBBIDHD@F?FHEDCHF?A@DAHIBHHHDBHHBIDDCGFGH?IHIIDE@BGCHIAEHA-ECDIHAC@DBFHICCD@
@>chr21:9908426-9908622-1
CTCATACCACGCAGCATCTGCAGACAGAACAGTACCCCTTGGGACTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGC
+
AEIHHAB?DIH?DIGBGEGDIB@CBFB!G@HBA<GBBAGCB?FDIICFG@GA@FEB@AGHC@B@BGEC?FHGBC?E@AIB@B@FHIHDDB@CIF??GHFE
@>chr21:9908426-9908622-2
CTCATACCACGCAGCATCTGCAGACAGGACAGTGCCCCTTGGGACTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGACCAGTCTGGCCCTACCCAGC
+
H@DGAGBFGIFAEHBC?'CF@HIGBCIHEBB@?EBB?GCDFCBEFEHFHHHHAHIFBG?@H@?GDFDHED?AACH@IAFIIF@FDCFID4BHHGDBFEAB
@>chr21:9908426-9908622-3
CTCATACCACGCTGCCNGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCCT
+
@?A?GCFHEFF?BGBB7@BD@@C@ACFHEF@HF??HHAFG@EDDHB@@E@DIHGGA?AEG?GACIEC?E(?HCDH@?CFC?IFHII?HHFGAEDBBF@CH
@>chr21:9908426-9908622-4
CTCATACCACGCTGCCTGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCCT
+
H?EBE?CDGB?C@BF@HG?@FFGFHBIHF?EI?A@GECHD@H?E@E?@G?EDB?@AGHFED?IGF@EEB?IAHAEHBCIAIDDEA?HCEAHBCCDD@AF?
@>chr21:9908426-9908622-5
CTCATACCACGCTGCCTGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCACATTGTCCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCCT
+
@FFABG@ADII@EB?BCAAGEBAEIADB?FABH@CAGH@DGBEDDDB?A?IDD@C6@BG?D?A?CFBAGAI?BI??B?FAGAEAFI@EGCD?GCIGIA@F
@>chr21:9908426-9908622-0
GAAGGTCCTCAGCATCTGCAGACAGGACAGTGCCCCTTGGNCCTGTGCCCCCATACCCGGGCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGCTA
+
DBIGCFH?IBF?GEHH?@ED?IGHIBHDICIABA??IDCC<CG?HE@IBEDHBG$@EEG@GEHH?DA?IC@GA@@I?AFBIHAECC??DI@IDH?BCGE*
@>chr21:9908426-9908622-1
GAAGGTCCTCAGCATCTGCAGACAGGACAGTGCGCCTTGGGCCTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGGCCAGTCTGGTCCTACCCAGCTC
+
AEA?GAFHI@EH?DBC@GBDGBAF?DBC?FAHC7@DHE?FGDBAB?ADE"BHEGFEC@G@G@EEEEHDAGA@D@FGH=IHC@E@DD@?GFCFHD?EFCCB
@>chr21:9908426-9908622-2
GAAGGTCCTCAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTGTGCCCCCATGCCCCGGCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGCTC
+
GBIHHH@HG?BHICIDAI@D@A@DB?H@HGFDCEIDHFIE?FBCH@@IEH@?FGB?F?"@CE@?GIE@G@AFFEF?HBHA?@EBICEEAC?EGA?ID?FI
@>chr21:9908426-9908622-3
GAAGGTCCTCNGCCTGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCANATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCANCCTCT
+
B?DIADGG@D#?IDD@HD@FCDADDEIDC@H??IF?EEED@HADBD?4CAHBDGDD??IICEGE@DD@DIG??A?@HE?BCAAIAIGFAHIF@B(DEGFF
@>chr21:9908426-9908622-4
GAAGGTCCTCTGCCTGACTCTCCAGAGCCCGCTGGGGGCACCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCCTCT
+
I?HIBBBEH?FIC?EIHBIGAAHDI@?HFHF?ABDC?BC*BCB?IDFF???FBHGC@EIC?DDDAEGEHII??@?HGIGBFBADIEFIH??DIADFFEEA
@>chr21:9908426-9908622-5
GAAGGTCCTCTGCCTGACTCTACAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCCGCT
+
EGIEAAABGDC@BFIECAE@A1?AEAEDBIH?CAABEGB@?HBD?FAG?G@AD@?EFDFIG??ID?C@?@IACGCFF?@GGGEFCC?BCIDIIAFAI=AE
@>chr21:9908426-9908622-0
GCGGCGTACAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTATGCCCCCATTCCCGGGCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGCTCC
+
GB?ICFDAAG?EI?ECB@C%G@AB@IEAAGAGH?DFEGGGCCE/?DF@ADEIA)F@GIEEDHIBDAEEGAEHCHI@I@ADIF@HEBA@CHGH?HDI?DHI
@>chr21:9908426-9908622-1
GCAGCGTACAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGCTCC
+
GH1@F?EADD@B?GHHH?D?HB@CDGH@IAEDGA?DHE?C@CB@?GGHEBA?AD@I@@@HCBFHCAHCEAEAHICICCDDIAA?DI@HCCG@C@II@ABD
@>chr21:9908426-9908622-2
GCGGCGTACAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTGTGCCCCCAGGCCCGGCCATATGGAATGTAGAGACCAGTCTGGTCCTACCCAGCTCC
+
E?G@AFGIGEC@G?BAICGAHIGGEDBDGEGEAH?HFHAB?HD@GHEDGCEE<HGCIBH!IEAAEDGGB@BE?AIED?@?HHC?EBHIHDFDBEFECCEF
@>chr21:9908426-9908622-3
GCGGCGTACTGCCTGACTCTCCAGAGCCCGCTGGGGNCCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCTCCCTCTG
+
@@EGAE@A?CA@AIGF?HHECB?G?@CHID?CIDBB=ECEGIBBE@IBA@FDHHBFF?B?@AGDIH@AAEDICE?D?E@EBDFHGD@?@G?C)C?C?EIH
@>chr21:9908426-9908622-4
GCGGCGTAGTGCCTGACTCTCCAGAGCCCGCTGGGGGNCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCCTCTG
+
BDGIH@EE0HFEE@IACBCEDED@?@FBB@HAGDHAD)I?ADIG?CCAAD?EE@DCD@?AHICDCDIFIA?DFEDCH@FIIDIGIAA?DDBF?@ADFDHH
@>chr21:9908426-9908622-5
GCGGCGTACCGCATGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCCTCTG
+
CBCGGGGAE1BH&IDACGD???EEDC?FDBFEFB?EGGCACG?FE?HHAHIACBCCAFFDHBBGBIB?@?EEA@FFGCBGH?EGABE@IDGEGEACIBH?
@>chr21:9908426-9908622-0
TCAGACGGTAATCAGCATCTGCAGACAGGACAGAGCCCCTTGGGCCTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGACCAGTCTGGACCTACCCAG
+
FGHAEGIEEF?IFDHEEC@AA@@BA??EBEAA@<?CB@GH?FAGIAFCHIGI?E?D?CIAIC?@FFD?HG?IBIFCEGFH@IEHGFG?B?!H@EE@GGIE
@>chr21:9908426-9908622-1
TCAGACGGTAATCAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTGTGCCCCCATGCCCGGGCATATGGAATGTAGAGACCAGTCTTGTCCTACTAAG
+
GBAFE@BEBC@B?I?CAH?FIBAHGAIGACHCCCB@EDDHFGH@@D??ED@DH@GHHCDE?EFAIFE?GCEBDD@HF@HDC?EBDF@I1DGI#AGC"3E@
@>chr21:9908426-9908622-2
TCAGACGGTAATCAGCATCTGCAGACAGGACAGTGCCCCTTGGGCCTGTGCCCCCATGCCCGGGCATAGGGAATGTAGAGACCAGTCTGGTCCTACCCAG
+
GEHIDIICGBI@AABCDIAC?HEIFB?E@ABG@AH??HI@C?AD?EEGDA@EDDGIHF?FCE@IB@EG'@F?@E@FC?AA@AF?AG?I@BCDBCCCAD?C
@>chr21:9908426-9908622-3
TCAGACGGTAATCTGCCTGACTCTCGAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCC
+
E@?HGF@@BCEFGIDIC@FCED@@?(HBDGHIG@CCAHGF@BAHDDACHFG@GG@F?IGACFIHB?B?BBHADEHFB?@AC?FFC@HBHDAFCBIEDFAG
@>chr21:9908426-9908622-4
TCAGACGGTAATCTGCCTGACTCTCCAGAGCCCGCTGGGGGCCCCGTGCACATTGTTCCCCTCACCCACGCCTCCCCAGGGCCACTGGTCAGGACCACCC
+
E?DIDCEEF?F@AFBE?GH?@?IDCCFFC?IFABFEEFGBDFIECDFEBH@IFHBDF?FG@BIIGBCFCHAH?I??EIBCIGB?EFFIECDEACHGGD?A
@>chr21:9908426-9908622-5
TCAGACGGTAATCTGCCTGACTCTCCAGAGCCCGCTGGAGGCCCCGTGCACATTCTTCCCCTCACCCACGCCTCCCCAGGGCCACTCGTCAGGACCATCC
+
AHGEED?FEHHBIIF@IH?E?CAGCCCC@AB?EBEGIB3FGIAGDBG@?BG@HB1IDFHAG?@IBH@A?E?EBHHEDHD@ECBFIA"EHFHEHEDCB%C@
@>chr21:9910146-9910226-0
ACCACTATGTCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTTTCCTTGTGCTCAGCAGCGACGAAGAGCTGAGATCGGAAG
+
EAB?@IAIFCAE?CHEE@@EDGCAICEG@DCGFCEEIC@EE@HBE?HDADGC@IABDB??BHHEGCBFAIHI@BGHG,E?DIFEA?CCIGACGIF@FCFG
@>chr21:9910146-9910226-1
ACCACTATGTCTGCAGGTTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTGTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGAAG
+
CIDBDDGHCBED?GDAG:HGHEDAGHBBCFB?DIEAF@FEEGBF?EFACIHBBHCADIEE?@AIDEHIEGCCGCI?CFE?BE?EIIDIBF?EAGB?G?IH
@>chr21:9910146-9910226-2
ACCACTATGTCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTGTCCTTGTGCTCAGCAGTGACGAAGAGCCGAGATCGGAAG
+
HHD@AFAI@B?BCHEBDDGFIEGGCEBFD@BA?E@DHGIDD?I@IGHABCBIFE@III@?GE@?HHAFDFEDAF?EH@IGI@HD@IHI5DAGFG?AG@IE
@>chr21:9910146-9910226-3
ACCACTATGTCAGCTCTTCCTCACTGCTGAGCACAAGGACAGCCGGCCCAGAGCTCCCTCCTGAAGTGGGCATGAAGACCTAGCCTGCAGAGATCCGAAG
+
GB@CD?F?CFBIGIIA?II"FB@EG?FBIHCHI@IAEFGBBC@AHIHBHIDEIDFFICFFDFHBB@.BCIA@C@HCB4?-FB?FICCE@II?EEG8?HIE
@>chr21:9910146-9910226-4
ACCACTATGTCAGCTCTTCGTCACTGCTGAGCACAAGGAAAGCCGGCCCAGAGCTCCCTCCTGAAGCGGGCATGAAGGCCCAGCCTGCAGAGATCGGAAG
+
CGIDHCE@AH?B@AEIAAFFFBBEIDIHBIFFEABI??IFFFEA?BCFEAIC@ECCCEFE?IIB?F?C?FCGF@HHEADH4CCFFF?CE?GF@@GDBF@F
@>chr21:9910146-9910226-5
ACCACTATGTCAGCCCTTCGTCACTGCGNAGCACAAGGAAAGCCGGCCCAGAGCTCCCTCCTGAAGCGGGCATGAAGGCCTAGCCTGCAGAGATCGGAAG
+
BIF?F??GBHCI@F3CECEEHACE@FE*#@A@?GCIEABBEEAB@DCBBBBEEGC@HAIEGBDGBGBFID@ABECCD@FA@IBC?F?EIDEF@?EF?I?A
@>chr21:9910146-9910226-0
CTCATACCACGCTGCAAGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTTTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGAA
+
AHD?D?EDF@BBBGDE1@FBGCACEAHBIEFIDDB@?FA4BFBB@HEIDCEGIGHIACBACBF@@AGCCFCGCD@BDBCCHBC@BFF@CFC8CFG@GCAG
@>chr21:9910146-9910226-1
CTCATACCACGCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTTTCCTTGTGATCAGCAGTGACGAAGAGCTGAGATCGGAA
+
C?E?BF@EDAFHICCACHCH?E@AEGI=FIAACGD@?@IGBIFGDDFEI?@?GIFFC@HFBE?E?FEFI?6CCA?G"HGBIDFBA?BAI?HICC???CGD
@>chr21:9910146-9910226-2
CTCATACCACGCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCNGCTTTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGAA
+
BB?HGB?FAFIDFGH@CBFIHHEGFIABICDICCID@DAHCB@??@ADCIEDHEIB@%I@HHH@EFIEABGHCEFDE??GCA@IHAA@DEIGBHG@AA@F
@>chr21:9910146-9910226-3
CTCATACCACGCAGCTCTTCGTCACTGCTGAGCACAAGGAAAGCCGGCCCAGAGCTCCCTCCTGAAGCGGGCATGAAGGCCTAGCATGCAGAGATCGGAA
+
HE@G@BH@?GGEHBDACBDIA@EDAFFF@@DCCG@A@?BIADBHCCDGB@?GBIFDHBADACICIBDF?CII?IGHF@HBC@BBB9IBFAEBBD@EDB@I
@>chr21:9910146-9910226-4
CTCATACCACGCAGCTCTTCGTCACTGCTGAGCACAAGGAAACCCGTCCCAGAGCTCCCTCCTGAAGCTGGCATGAAGGCCTAGCCTGCAGAGATCGGAA
+
?EEIIG?H@ECCIHDIFHFDDCADH?@BFI?E?CIFIE@C@D3AD?(HDGB@@G@FIIG@FDB@FGCA(IBEI@CEIEAEHDABCDBEFFIBCFGFDBI@
@>chr21:9910146-9910226-5
CTCATACCACGCAGCTCTTCGTCACTGCTGAGCACAAGGAAAGCCGGCCCAGAGCTCCCTCCTGAAGCGGGCATGAATGCCTAGCCTGCAGAGATCGGAA
+
D@AAAG?EC@HI?@FGCDH@BCBI?HI?ICF@ABCGGCBBH@?BBEDEBE?D?HABBIC??@H?IIDDDDE@DIBFB2AGDI@=DEH?D?FICACBDBBD
@>chr21:9910146-9910226-0
GAAGGTCCTCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGATCTGGGCCGGCTTTCCTTGTGCTCAGCAGTGACGAAGAACTGAGATCGGAAGA
+
E?DIFACH@B?BI?FBAD?@BB?@HB@GDG?C?BGFAA?GHGCHGA8ADC@A@GF?GF@IFCGGHH?BIH@I??HADCCDEAIGI"?IG?ACHGGFBBED
@>chr21:9910146-9910226-1
GAAGGTCCTCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTTTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGAAGA
+
FHHG@F@EGDIAA@CIID?DEHBCCH?AHFGBAD?D?E?GGBIGDDDHAIBHD@HEAG@EDBDBCCGIGEI$EHCG?D@FF@EH?GFIAEGGH?CBIA@G
@>chr21:9910146-9910226-2
GAAGGTCCTCTACAGGCTAGGCCTTCATGCCCGCTTCAGGANGGAGCTCTGGGCCGGCTTTCCTTGTGCTCAGCAGTGACGANGAGCTCAGATCGGAAGA
+
?@??HIF?DBG2@GAEGGCCH?BBDA?DBEDHEGBGABADA/?AAHCHDEHGBAAHGHH?HI?GHD?HHGAB@?H@@E@?@G7;D@E?$FIF@BBHIDAA
@>chr21:9910146-9910226-3
GAAGGNCCTCAGCTCTTCGTCACTGCTGAGCACAAGGAAAGCCGGCCCAGAGCTCCCCCCTGAAGCGGGCGTGAAGGCCTAGCCTGCAGAGATCNGAAGA
+
GD@ED$H@??IG?EBB?EFBA@GBGCDI@HIIH@EG@DAB@?HAC??CC?IIIHAHI5@BD??FDDHAGA5EGBB@@FD?DDI?EIB%BBGID@;EIF@G
@>chr21:9910146-9910226-4
GAAGGTCATCAGCTCTTCGNCACTGCAGAGCACAAGGAAAGCCGGCCCAGAGCTCCCTCCTGAAGAGGGCATGAAGGCCTAGCCTGCAGAGATCGGAAGA
+
H@B?BH?;GF?FAF?AAI@"BBGHIB;BAEBI@@ABDGFDHCE@CG?GIC?F@B?IDACCDEGGI.F??BAC@GHDG@E?B@DDH@CHE?FGAEIEHCAD
@>chr21:9910146-9910226-5
GAAGGTCCTCAGCTCTTCGTCACTGCTGAGCACAAGGAAAGCCGGCCCAGAGTTCCCTCCTGAAGCGGGCATGAAGGCCTAGCCTGCAGATATCGGAAGA
+
G@CF?IG?HFDFBCF@?@F@HFCB@IEHFFA?HCDBD?IGEBCDHEIIFEIE0GG?GFGG@IEACEABAGEAC?F@D@?CFFD?GBD@??4HIECDEAH@
@>chr21:9910146-9910226-0
GCGGCCTACTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTGTNCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGAAGAG
+
G@AAC,HCFCCGFCGHE@IDAB@FB?EE@BFDFAIFEDCBAGF@@DCDEC?@?DCFDIIC*@DFBDCFBBDFFIIDCFGC@D@?DD?ADG@GFBHC?AFB
@>chr21:9910146-9910226-1
GCGGCGTACTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGGCGGCTGTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGAAGAG
+
G?G@EIGADGFFECFEHFFGC?CHIBF@EICG?$@BC@?ACEACF?.EEAED2E@FBAF@HD?@@FGHH?CDCIIIB@A?@@C@A?EAB@F@GEBIIGHI
@>chr21:9910146-9910226-2
GCGGCGTACTGTAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGNGCTCTGGGCCGGCTGTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGAAGAG
+
CAH?IBE?DIA#I@DIAC@CICAEADE?E?AEC?@IF@FCBBG#FI?C@?ICCE?G?IE?FB@B@AIHCIE?B?D@GFIGGBFD?HDF?@D@@?AHAGBH
@>chr21:9910146-9910226-3
GCGGTGTACAGCTCGTCGTCACTGCTGAGCACAAGGACAGCCGGCCCAGACCTCCCTCCTGAAGCGGGCATGAAGGCCTAGCCTGCATAGATCTGAAGAG
+
EDFA6EAHHCDD?H>FGDE?B2DI?CHFBFA@HFIBDBB@BGGDHCGI?I8FHDBE@CCEHIHBBFIEDEGEHC?CA?G:BFCIBI?*ADA@G&G?IEBD
@>chr21:9910146-9910226-4
GCGGCGTACAGCTCTTCGTCACTGCTGAGCACAAGGACAGCCGGCCCAGAGCTCCCTCCTGAAGCGGGCATGAAGGCCTAGCCTGCAGAGATCGGAAGAG
+
?BAFEGCBIGBD<CGBHACDCBFI?A@EHC@IEA@D@BB@CFDC??HGI?HBGDEHCB?B?GEIFDICGBHEIFGCDDBD?GCEEECHFC?@B@DAFEIE
@>chr21:9910146-9910226-5
GCGGCGTACAGGTCTTCGTCACTGCTGAGCACAAGGACAGCCGGCCCAGAGCTCTCTCCTGAAGCGGGCATGAAGGCCTAGCCTGCAGAGATCGGAAGAG
+
I?EGACACDIE!A@BGAGD?EGB@FDIEG@GHB@B??I@BEADDAB?CGHBCDE3??C@B@AFII@EF@@@FDGAHCAFFHGIGH@GCB@BEAE?B@EBE
@>chr21:9910146-9910226-0
TCAGATGGTAATCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTGTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGA
+
DFG??*@DECAGCG?BCB@E?GIHBIEAFAFCIC?GBBFFE@IC@C?ADHFGG?@IBBAFGGGGFABGD@CHCAIHFFD@?BBCHBICAAABGAF?H@BH
@>chr21:9910146-9910226-1
TCAGACGGTAATCTGCAGGCTAGGCCTTCATGCCCGCTTCAAGAGGGAGCTCTGGGCCGGCTGTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGA
+
BE@G@@CHD?@@ECEBEDDF,B?CBB?IGHBIFDFA@DHII/IBFGDCFCBGG???DBFBDAEI@AF?BH@@EF?@?CCFHECB@AABHDFD?GFCCIFI
@>chr21:9910146-9910226-2
TCAGACGGTAATCTGCAGGCTAGGCCTTCATGCCCGCTTCAGGAGGGAGCTCTGGGCCGGCTGTCCTTGTGCTCAGCAGTGACGAAGAGCTGAGATCGGA
+
BIDEGBDCAI@HEBCEADACAF?A?H@??@BEFI@BAFEGEIHGFGBFEFAFFBBF@?IHAF@HGF?@IIF@IEA@DGEC@BIEAGCBFB@IIII?CCID
@>chr21:9910146-9910226-3
TCTGACGGTAATCAGCTCTTCGNCACTGCTGAGCACAAGGACAGCCGGCCCATAGCTCCCTCCTGANGCGGGCATGAAGGCCTNGCCTGCAGAGATCGGA
+
II;?HBAE?@H@GBHCBHEFG@=H?HBDDHCI@@IBG@H@IGGBABBD?H@B!FABAEDEAIDI?I'FCFEB@DCEFBDB?FG8GI?AIHHDF@IBC?DC
@>chr21:9910146-9910226-4
TCAGACGGTAATCAGCTCTTCGTCACTNCTGAACACAAGGACAGCCGGCCCAGAGCTCGCTCCTGAAGCGGGCATGAAGGCCTAGCCTGCAGAGATCGGA
+
E?BICFAABEFCAC?B?AAC?CBBIID-HC@F%@FBHA?HI?GACBG?GIEBHIAC@G+DE?GEF?@C?CAEE?F@?AIIGEBGAE@F??DCDF@F@GGA
@>chr21:9910146-9910226-5
TCAGACGGTAATCAGCTCTTCGTCACTGCTGAGCACAAGGACAGCCGGCCCAGAGCTCCCTCCTGAAGCGGGCATGAAGGCCTAGCCGGCAGAGATCGGA
+
CA?CEADHFFBEHH?HECHHAFIE?IBCIGDBDGEADFHIFCBDGFDB?IACHEHIFB?CCEDDBBACGEFGICDFGBCHFCFDFGC$GBBAGIDGDDCE
@>chr21:9910243-9910433-0
ACCACTATGTCTGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTCGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGAC
+
CDH@FA*FBACGFCIIADIC@EAEDICAH?BEB?G?AEA?HFBGIBCEFEFICHFD?6HHADDIHAADHBGEHAIDABAHCIHAD?DG@HDAIGCHB@GE
@>chr21:9910243-9910433-1
ACCACTATGTCTGCAGATCAGTTGTGGCACTGGGCNTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCAGCCAGCCCTGTGCTCCCACTGTGAC
+
E@BIACH?I?BI?IIGGCBC@AGGFGDIEH?@FA?3?@DAIF?HE@AGFHBG?DEDHIGGBDAHGFIAHHBAGHA#C?IB?FEDAIDDHIDDDDDABEFE
@>chr21:9910243-9910433-2
ACCACTATGTCTGCAGATCAGTTGGGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGAC
+
C?FAEIHCE?I@?BBHBF?CAIGE!CE@GHGIGDFB?CDAC?C@?ABDICDEFFDFIH??A@@BCHD@CAFBABGECAECBGDDABFFA@AGG@?EG@@?
@>chr21:9910243-9910433-3
ACCACTATGTCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAGGG
+
@D@@IIIBB@EHGAAFABCAD@HF?FGCDHEG?@EAC@G@H?DGBC?G??FIEIGA?BDCECDEGGAB?FGEED@?EBGG?CCF@@@IHG?HFAFCCBAF
@>chr21:9910243-9910433-4
ACCACTATGTCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGTATGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAGGG
+
G?@@D?G8FHAI@BHHHABEBEIEBFFIHEFGE@GEFHEEDBE@HFFBBHF9FHBC"ABABCHIADD??CDIF?AGAHBC?IC@AG?I@CA?ICBI@@I?
@>chr21:9910243-9910433-5
ACCACTATGTCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCATGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAGGG
+
DC@EH??GDIEC@GHHHAIIG?GEIFFGEF@@EHIFEIIEBIDH@ED?CFFBIDA?AFEH?@ED@BHFHDEBCG@BC??ID?AD?II@CIGEFDB?CIAD
@>chr21:9910243-9910433-0
CTCATACCACGCTGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGTTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGA
+
@DE3?ECEECGABIGGGHCFAEIA?FFFGIDCEGAGGDHCG@I@EHBAH?DECAE?EDEGH7DABFAADDFIF?EG?FBAHHCIEB?IFFHGCH?BIAH?
@>chr21:9910243-9910433-1
CTCATACCACGCTGCAGAACAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCANGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGA
+
HCGAGGCGDHA?EHECB?%BIC@@IICDBAI?DHG@?C?F?ICEDI@B@?HA@G!?HFDAIHBDHABEC@EGHHHHCDBBGEEEE?@DG@IEG@DC@AGD
@>chr21:9910243-9910433-2
CTCATACCACGCTGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGA
+
HIDAEBCFIDDIEE@@FCED@IAA@AF?@EDABHGCIDIEF@FDG?CGADDFFDECB??BCAB?BD@DA?GCAABCDBIIFEBAGHCDB@CDHECHGFIC
@>chr21:9910243-9910433-3
CTCATACCACGCTGCCCAAGGGATGACTCCTGNCCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGGAGG
+
IDIBHDC@ACHDBD@I?@?EEEAFDHDC?ECG5CDH?GHIIDGIGE?AFIHHDH?IHD?AEBCFD@FBGDAA@F@IDEEBHHGIGID?GCFBGBHG3FGH
@>chr21:9910243-9910433-4
CACATACCACGCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACTCTGAAGCTCAGAGCCGGCAGG
+
E0D@HBDC@@AIDEBH@GF?D??DAI@?CEICAFB@ICDEGIIDC@FHDGCEE?GI?FBCICHF?ECEBIE@BHDDHH(CIDB?A@B?GEHBFGBBI@CF
@>chr21:9910243-9910433-5
CTCATACCACGCTGCCCAAGGGATGACTCCTGACCGCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGNAGCTCAGAGCCGGCAGG
+
AFC@FD?DA@DGEF@CCEHB?DBBBBDCBAADC?E#HDBICEBDABDEAIAECIEBC?AIDFEFAHDICED?FGAC?I@HA?)EG?G@GBHDDAC?HAEE
@>chr21:9910243-9910433-0
GAAGGTCCTCTGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCCGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGACC
+
@@@EGICFEGB??DHG%?BI?GA?I@??@?FFBIBIABFFCEF@DIECGH?AGG@<GACEDBAICGFI???DDAEH@CHDCG?GD?IAACG?CFH?ACBA
@>chr21:9910243-9910433-1
GAAGGTCCTCTGCAGATCAGTTGTGGCACTGGGCTTTGGCTACTCAAACTCAGGCTGGGCTCGAACCTCCACCACCCAGCCCTGTGCTCCCACTGTGACC
+
@EADIHHFCIEIEEHGDFAAG?@CI@BED?F@AFE@EGCF-IEECFADBIHFAID(GBDIB"BGHDFE?C=A??EHAEDCG?DC??IA?FCAFB@ACEAE
@>chr21:9910243-9910433-2
GAAGGTCCTCTGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCGAGCCCTGTGCTCCCACTGTGACC
+
AGFEBDHHDEACGAG@FDBG@FHGI?IAEG@HHFHBAIDDIIBCIA@EC??@HCIH?@AI?@EGHDDI@BADDBGA%?GFECAIDIEFDIBIADBHHE?A
@>chr21:9910243-9910433-3
GAAGGTCCTCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAGGGG
+
BF@E?EGBBFHHEB?@DFHIDGBGGAHCEEF$IGADCF@EHC@HAG@F??@GF@F?DB?@HHBFHF@CA@ADD?HAA?ACB@I??FFGE@GFIBCGAIAD
@>chr21:9910243-9910433-4
GAAGGTCCTCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCATGGCANTGAACNACAGAACCCTGAAGCTCACAGCCGGCAGGGG
+
G?@BG@BEDA?@@?ICEFFGABEDEBCE@E?@IIIB<E?GABAGBFCAFDCAAHAHFADDDI*?CGDC<A@GDC?EDIDICGCCEDC7B@HHAIIFF@AC
@>chr21:9910243-9910433-5
GAAGGTCCTCTGCCCAAGAGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCATGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAGGGG
+
EIGB???CE?AAGIGBDI!HDDBFCAFGIH@GGADAADAIGA?IFFFHIDEHGGBCDBFBD@D@EEB@CBFEBDBGHEF??F@GA?E?BACABCEBDAAE
@>chr21:9910243-9910433-0
GCGGCGTACAGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGACCT
+
GEDAHDGCD1ID@IFFAD?EEGBF@IGFFFGA?IG?GHFDAH@A@HAFEGGEHBFGGFFCIE?IIBDBGF@BEF?A?EHH@DGCH?GC@HHEC@HAEA?F
@>chr21:9910243-9910433-1
GCGGCGTACTGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGACCT
+
IE?DE?BDGF???EEFFHC?C?BHFBDAGGBEAGAFIEHDF?GFCI@CFHGCB@GHACB?EF@E@GBAB@@HE@EC?I@FFGDHFAGFG??BFCF?>E@A
@>chr21:9910243-9910433-2
GCGGCGTACTGCAGATCAGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTGACGT
+
@BE@C@ECC?A?IFDBBFEHFDIFC1CIGCAAE?DCBDEDGABFFFG@BEAFHGIF@DEGHHEDF?FBFAADGEFCDE@IF@H?GH??@@DACGEFGA,G
@>chr21:9910243-9910433-3
GCGGCGTACTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGNCGGCAGGGGC
+
HGEE?IHE@@FIEFIDHFIGE?F?HABEHBHBB?HAIDCEGGFHIHBF@BHG@FBFGDI?CAIHH@CHEEA@IFECBHFHECD?CAADG%@?HHEHBFDC
@>chr21:9910243-9910433-4
GCGTCGTACTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAGGGGC
+
G@B.ADFH?C@ECH?F@FBEGDCGF?I?BCGICIA@@CAI?AC@HIF?DHHBDDDAAGBG@IFGDGAGH@@CC@HGEBBDI@EA?CGIEGCFHCIDI?@D
@>chr21:9910243-9910433-5
GCGGCGTACTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAGGGGC
+
??BDIB?GFB@AABGF?EBDFDADH@AEA?CF@CGCGHEDGAGIBFF@CBBCADBDF@?CFABIGCC@FIDIDFADHEC?FI@DBDABBGG?BIAGEDEC
@>chr21:9910243-9910433-0
TCAGACGGTAATCTGCAGATCAGTTGTGGCNCTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTG
+
I@BGHHG?EDFFAEE?GG?CDHGIGB?FCF,D?HCBAF?FFIACICECEBFEIDECABDGAEDIIID@AHFE@DIHACCC@DBC@E?@DDBFHIHF?FFB
@>chr21:9910243-9910433-1
TCAGACGGTACTCTGCAGATCAGTTGTGGCACTGGGCTTTGGCCAGTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTG
+
BCAF@IHA?C;HD@?C?BGDDIACFB?@I@DH@FFGA@?B?BFAD0E??BE@DAI@?AIF@HAEA?ACB?EEIDD??FFDICFEC?ACCCA?@IAFIFHE
@>chr21:9910243-9910433-2
TCAGACGGTAATCTGCAGATCNGTTGTGGCACTGGGCTTTGGCCACTCAAACTCAGGCTGGGCTGGAACCTCCCCCACCCAGCCCTGTGCTCCCACTGTG
+
@FD?IFCFBHBFEG@@HIE@D#??HFFB?CCFCDCEECD@GIGDACI?BAI7HG?EC??@GD?GFCFCBFGAHEBCCAFIGAG@HAFIID?FE@IBGD@C
@>chr21:9910243-9910433-3
TCAGACGGTAATCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAG
+
BAIHAH?EG@I?BAICA@GDDB@CE?BAHICG?CH@EHAHFBBG@EHHGDEHBDBBEGDCEBIFHGF?AAAIHC@GEBAEBAFIFH?GDHFIEIA?EECB
@>chr21:9910243-9910433-4
TCAGACGGTAATCTGCGCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAA
+
BEI@HG@H??FAD@DI,@@FGIBB?F@B@FDAIFIBEGHDBBDFAFCA@BAGBHEGGHFE@IG@BBD?I@?DIGBEHBEIIADHCDF?DEHE@HEAE@F$
@>chr21:9910243-9910433-5
TCAGACGGTAATCTGCCCAAGGGATGACTCCTGACCCCACCCACGGCTGGTCCTGGGGCAAGGCATTGAACGACAGAACCCTGAAGCTCAGAGCCGGCAG
+
EI@DBHEFBDIECADI@ABGFFDG?FDGFIFB?GHAFDIHH@@CF@CIGIAFCFGGA?CD@?@BH?BDH??G?EDCIADEEAHGBH@?CCF?@EEC?IHG
@>chr21:9910430-9910485-0
ACCACTATGTCAGCCCTCTACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
E@??BCCEGHAF@AD@D?"IB@GGHEI?D@HFFF?I?D@GCD?GFHEAIG@IFBDHIGD?@@CDAABFA?BBB?EGE@@BDE??GEEBBE@EDHABFA?H
@>chr21:9910430-9910485-1
ACCACTATGTCAGCCCTCGACCCAAGGGTCTGGCTCACTGATTGCACGATGGCTCTCTTCAGCAGAGGTCGGAAGAGCGAAAAAAAAAAAAAAAAAAATA
+
I?BICA?@BHH@BHAEIBFC@IDA?@B?CHIHCG@EICAF$BD?A@FGF?A?HEAFFBIBC?@FE?D9A@@ECGGEEEDFAGHDGEFFII?FAICAC?%H
@>chr21:9910430-9910485-2
ACCACTATGTCAGCCCTCGACCCAAGGGTCTGGCTCACTGCTTCCACAATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
?GHGAIBA@GGAEHCFCCDIFHG?BGCGE?G@@?GIGFGID@H6AGF3AIAAHBFIAC@IC@G?HCAHDGGB?C?AHE@?IADHDFD?AIGH@EGI?AIG
@>chr21:9910430-9910485-3
ACCACTATATCTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
BA@@DECB7CFE@HGCDEHBA@BEIE@DFEBAEFEGG@@A@CCCFE@AC@CEIFEEFHH?HFCFEHIAIEA?F?CE?B@FHFFEHDEIBBDIDDBBICBG
@>chr21:9910430-9910485-4
ACCACTATGTCTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
CDADI@?GEBF?GDHFCA@CECAHIHCDCFDBG@GGI???E@DGFIGEDABI?DHGFICD?G@?@BF?DECHCBGGF?@?DEBECIH???3HBBFIHI?D
@>chr21:9910430-9910485-5
ACCACTATGTCTTCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
EB@@DH@IDD@?#?AAIEAICIFBHDGI?BIIGDAI?FB?HCFHECACEHHI@DAHFDBBDH?CEB?GCG@GGEC@AFAHBG@?GF?EAI?CDHBBHCF?
@>chr21:9910430-9910485-0
CTCATACCACGCAGCCCTCGACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGNAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
ICIGFA?BB@GHFACA?IGFHHDIHFC?HFAIFDBGHACGHI@AED@G@A@@?ACIHFIHFE@CGDFA@AAI,CDACB?HH@BDAHFE@BFACFDC@DGE
@>chr21:9910430-9910485-1
CTCATACCACGCAGCCCTCGACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAGAAAAAAAAAAAAAAAAA
+
IB@GBG?B?IF?GBCDC@IF@GHFFIHCIDFH?FGFAD@?GIEHAADH@FF@DE?@DBADH?AGBCCIDHG?EAEGAEG@H?'FE@CFCHF?HAECH@HH
@>chr21:9910430-9910485-2
CTCATACCACGCAGCCCTCGACCCAAGGGTCTGGCTNACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
BFAA?@IFHG?I@AABFHAGEFEG@HIHEFG@CCFI:H@HIIHF?HBIHDIGB?GDDCGAF@E9AIIG??BHACCEAEHDHCF@AEECFC@CC?A@II@B
@>chr21:9910430-9910485-3
CTCATACCACCCTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGTAAAAAAAAACAAAAAAAAA
+
BFCFBCAHFD=II?AEGIDE@GEICCCHDGEB?EA@DDI?CDH@BCCEIDEAH?H@HI@H?HIFIGAB?EDGEC@@FAAC*G@?GDFIAE6G<BEB?IGB
@>chr21:9910430-9910485-4
CTCATACCACGCTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAACGAAAAAAAAAAAAAAAAAAAA
+
D@BI@BDEI@HDDDDGGE@FBHHCA@CE@IEIB?HDIA?E@DHD@AIGCEIEIHDID@FGAAAEAGECGDI?DFFCA>I??BAE?ACAGAEE?GGHAB@?
@>chr21:9910430-9910485-5
CTCATACCACGCTGCTGAAGAGAGCCATCGTGCATGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
CDHCGEEDEDAIGIDEEBBB?HAHDBHCC@EIHD)BCA<CADECD?I@@HEH@AEDFGGEHCA?I??FBGF?ID@H@ECD?IH?AGF?@FBBIAEB??BE
@>chr21:9910430-9910485-0
GAAGGTCCTCAGCACTCGACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAATAAAAAAAAAGAAAAAAA
+
HAEDHEBHCAE?B$FD@HIFFIGBIHCBCE?FAHIDDFF@FIIB@H?HCGDFB?IEC@FI?DEB@I?B@B?AHAE@DCII@D/?CBG?IC@I9ADCBFDA
@>chr21:9910430-9910485-1
GAAGGTCCTCAGCCCTCGACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAANAAAAAAAAAAAAAAAAAA
+
HBA?AHIEAGHDCG@EHCC?B@FC?EBH?HFBCHFDF@ACGEDIAICAAFBC?FICCACHIFEEFAAIGHHCA@?BCFHFI>@?FCFD@HG@?IG?EDEI
@>chr21:9910430-9910485-2
GAAGGTCCTCAGCCCTCGACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
EH?@EF@GG@IEADGIDIAFBBFDACEIEA??EHIIAGEHH(BHGI@C@CAG@DAGBEBEFGHABFFBCEGEHDDDICEI@HC@?D<GDHADB?E@DEII
@>chr21:9910430-9910485-3
GAAGGTCCTCTGCTGAAGAGAGCCATCGTGCAAGCTGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
@HEEEEIEFGEEBIBE@?FCADHEHHAHBCHHAHH%CCHHFH@IE?CFDHBFBBIBBD?C@?CED@C?D?IIDCABBGDBFHC@AC@HH@FDIAIB?HD@
@>chr21:9910430-9910485-4
GAAGGTCCTCTGCTGAAGAGAGCCATCGTGTAAGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
IDBBAACDAEBHBC?I?IBFAHBIFH@@CF-I?CAHCB@GABF@II?HFFBAAA?FHFHBFI?AAGFB?HGHHCEH@@GHIFGED@??GBCID?EGGAGI
@>chr21:9910430-9910485-5
GAAGGTCCTCTGCTGAAGAGAGCCATCGTGCAAGCAGAGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAATA
+
D@I?BGHEE@HHGF?ACDE?GHEHFHIEFGHAGCHEI2F?C??ABHHC@?FH@?CIADC?IFIBD@B?H?BBGAGGICGIHDBDDFHHBCFGEE?B@A3@
@>chr21:9910430-9910485-0
GCGGCGTACAGCCCTCGACTCAAGGGTCTGTCTCACTGCTTACACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCNAAAAAAAAAAAAAAAAAAAAAAA
+
GIIHDDD*BEHBICFIF@BEBDFABHAF?I9EAIEEIEA@E8CFCB?EG@@IHA@HCDBGAG@G@EBEGCA@AG@G9@@DHHFICHDFHEC@BD@DBHI"
@>chr21:9910430-9910485-1
GCGTCGTACAGCCCTCGACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
HIC:GG?FG@AEAEDHFBE@IADCAEB?CBFBGFCFBIIE?HCEEFDDI@?EDCHAGCDCAGCI@AE@EHHADEAH@F?HCCDDIA@GD@HGI@CAAD?A
@>chr21:9910430-9910485-2
GCGGCGTACAGCCCTCGACCCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
CGH@HB?ECFAECICH?DFII@EFAG?CAIEFCGDDGDIAHF?E?FEI@IDEDICEGAEDECECABDG?GGG@DB@I@A?HAI?H@FHGACIBHBA?HCD
@>chr21:9910430-9910485-3
GCGGCGTACTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGGGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAACAAAAAAAAAAAAAAA
+
GCFFEAGHGIFDIGDGDGA?@AEFHGG@EC??GFC??@EFGD@HGIHBBCABGD@IGEHHIB@AHHGG?BBIF@ICHFEEH@G?/AGAGGGEA@BFH?E?
@>chr21:9910430-9910485-4
GCGGCGTACTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGANCCTTGAGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
GBHEA?DD@HHIGHF?C?%IEGBF@@CAGGA?CICFGI@CACGGC"CFA?BBHC@A@D@ADAIIAHDDHABFCIBCA@F@BEIGIEB?IBH@G@EA@BCC
@>chr21:9910430-9910485-5
GCGGCGTACTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGAGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
IEHF?FFGE@ADECBEIDI?IADAAGGIECI@AHGIB?I?DAFG?HDH?BGGFCCHAE?BEAEFH?ABDEDCGCHAFCCHCEHDCHBBBA@HIDIFD@DH
@>chr21:9910430-9910485-0
TCAGACGGTAATCAGCCCTCGACTCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
I?EGABFI?@IGAEGIIDFAGAEFIBDF?FC?CAGEGEAAGFF?CF?AEEEIAGIHHIGA@ABCGEGIC@CEBD@I?GFCGFCDEEB?C?FFFHGAIGAC
@>chr21:9910430-9910485-1
TCAGACGGTAATCAGCCCTCGANTCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
DB@HFBDG@D@DHAADHCEFI?%G?@?EFCCAC@D@GD?FHIICDCG?HHAFFDHFBIEIHIAC?DH@D?D?ECEBAEDEGIFAFCDADIF@FGBDE@C@
@>chr21:9910430-9910485-2
TCAGATGGTAATCAGCCCTCGACTCAAGGGTCTGGCTCACTGCTTGCACGATGGCTCTCTTCAGCAGGGATCGGAAGAGCGAAAAAAAAAAAAAAAATAA
+
AHGDG-EIHA@EECDHFEBCC?B@HFGFFCHI?AF@GI?HD?BABBBIH?CHEHDB?GF?DIAFEHD=HA?A?D?HG?A@CB?EHFA@DI?BC?IFB!BA
@>chr21:9910430-9910485-3
TCAGACGGTAATCTGCTGAAGAGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGAGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
AFIEI?AAGF?GEB@EGBGAGB@?GFHEDCFCIBGEFFFFFCEACFG??GEDEGFGABEHIFF8CDDDFGE?IGDBFIA@A?@GI?DGCC?G?FHAG?G?
@>chr21:9910430-9910485-4
TCAGACGGGAATCTGCTGAAGAGAGCAATCGTGCAAGCAGTGAGCCAGACCCTTGAGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
?EDAIGDB)?BFE@FC?BG@@@DC?I(@:BCC@FIF@IFBICC@BC?BGBBDIBDCGAI@ECIIFHIGHB@IFGDAC@CEGHFG@?GBE??IDDGEF@BB
@>chr21:9910430-9910485-5
TCAGACGGTAATCTGCTGAAGNGAGCCATCGTGCAAGCAGTGAGCCAGACCCTTGAGTCGAGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
GICFEDGHD@GCFHCED@I@G8@IBA@DAABAAFBHIC@@FDFGFDCIBAHF?AEDFGF@@@ADEEGIC@?FEAGGFBH?CBEE@?IGCAECBCFE?AGG
@>chr21:9910482-9910580-0
ACCACTATGTCAGCTCCTTAATGTTCCGGATGGGGTTAGCTGCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAGG
+
@BGBCGID@G?AECIDIGAFABIIEHGHAEAIBE/B4FAEB@?FI@AIBBBGBDG@CHHHG?GDDGEDCDE@HGIH???G?DGEFHA@A/BFGGCAB?EA
@>chr21:9910482-9910580-1
ACCACTATGTCAGCTCCTTAATGTTCCGGATGGGCTCAGCTGCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAGG
+
CDG@IFEEBFBCIIIGEFG?HBAFC@DAIGHADHEHIDEHCIIFH@CAHC@@CFBEECEBEDGEH@BHEHCBECEDCGD?FIBABE?EHGCF@A?CIEIC
@>chr21:9910482-9910580-2
ACCACTATGTCAGCTCCTTAATGTTCCGGATGGGCTCAGCTGCCTGAGGGAGCAGNCGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAGG
+
@ICCHDBIC?DBAIIAFEFGCBA@HCFGG(?BIHAIFBEBGHGFCFCCIGDF-BI8ABFA?EEECCCB@FE?HCFE?@ECDEEH@BFEIAH?HDCCIA@B
@>chr21:9910482-9910580-3
AACACTATGTCAGCTGGGCCTCCTGGGATCCTCACCATGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGCAGCTGAGCCCATCCGGAACATTA
+
D0@BGF@G@?EACEAHEFIIG?EEBDGIEGGFDAFIB=@H@ICBIDD@FBEBEFCABI@H?H?I?E?GADIAF@EGAE@DGGCGCFGAFBBA?CG?DADD
@>chr21:9910482-9910580-4
ACCACTATGTCAGCTGGGCCTCGTGGGATCCTCACCAAGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGCAGCTGAGCCCATCCGGAACATTA
+
EDAAEIIIHH@H?BGBIDIACF"DADHFFHCFAIBEHB%GFCCHECGF@DDDGIBEFF@GCDE@CB@IAFCAA@ECI?DIGFDH?HCCCIH?@GCCCHEH
@>chr21:9910482-9910580-5
ACCACTATGTCAGCTGGGCCTCCTGGGGTCCTCACCAACGACCGGATCTGGTGCTCAGTGCGTCTCCTCCCTCAGGCAGCTGAGCCCATCCGGAACATTA
+
@@CAFFGF?AAHFHFFIDHBBD@AGAB7?BEECDFACC2DBHFAAEA?BEACF?FACA9FIE@FFEDDAE?AG@EFCDIHACA@??C??DDIGHGB?HAI
@>chr21:9910482-9910580-0
CTCATACCACGCAGCTCCTTAATGTTCCGGATGGGCTCAGCTTCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAG
+
BGEA@GIIAEEFEGCEICGIAEI@GGGFDC?AHFCEID@E@IGDHC?BFBI??DHDA?BCA?GBHGCBFAI@HI?EHCCFHE@?IFIIE?H?@FEF??@E
@>chr21:9910482-9910580-1
CTCATACCACGCAGCTGCTTAATGTTCCGGATAGGCTCAGCTTCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAG
+
?BGDAE@FIBG@C?FA/DDA@C?FF?F@EFGB'FE?ACGIGHHC@CFEICBCBBIC?HAABEE??HFCFBGGEI??AI?H?FH@FCEIIFCBEHEBCHFD
@>chr21:9910482-9910580-2
CTCATACCANGCAGCTCCTTAATGTTCCGGATGGGCTCAGCTTCCTGAGGGAGGAGACGCCCTGACCACCAGATCCGGTCCTTGGTGAGGCTCCCAGGAG
+
@HI?@DC@I+E@AICBF@IH@HBEDE?AHGHGDIE?@E?IFAD@HH@FGHC?CCDF@EHG?IGGA#IGHCGA?HG?BEDIAFDIHBBGAC*DGHI?BF?H
@>chr21:9910482-9910580-3
CTCATACCANGCAGCTGGGCCTCCTGGGATCCTCACCAAGGACCGGATCTGGTGCCCAGGGCGTCTCCTCCCTCAGGAAGCTGAGCCCATCCGGAACATT
+
AGIDFB@?@7EGHG?A@ECFEECGEDFAI?HHI?GE@GAG@FAFDG@@FADE?CF%?FFID@HHF?DEA@GCH@@?GEI@BI?EG?FDID?AEAEDHGEE
@>chr21:9910482-9910580-4
CTCATACCACGCAGCTGGTCCTCCTGGGATCCTCACCAAGGAACGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGAAGCTGAGCCCATCCGGAACATT
+
G@?BI??GIFGCIH?B?G;G@?EA?IAE?FIDGA@HAFIH?G1@BFC@BGCDD?A@BB?BEBEGE?HHCF?IAFCAAFG@@@?AI@GI@BD@G@BDC@D@
@>chr21:9910482-9910580-5
CTCATACCACGCAGCTGGGCCTCCTGGGATCCTCACCAAGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGAAGCTGAGCCCATCTGGAANATT
+
AFFAHFAF@IECEFEIGHGAHGI@FCICH@IAA?@DBB?AHIIGADGDA?E?DEICEECAACAHFAFDFDB@C@CDEBBGCE@F?FBDGEC-BA?G>BDD
@>chr21:9910482-9910580-0
GAAGGTCCTCAGCTCCTTAATGTTCCGGATGGGCTCAGCTGCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGCTCCCAGGAGGC
+
IEICEDBBCFDDEDGCH@AEGIIEDD??E??EFD@CGAFADBCBGIG@@DA@@HBDFEGD?IICABFACBDICFI?HB@GFIAECFAI!FDCIDAG@GDH
@>chr21:9910482-9910580-1
GAAGGTCCTCAGCTNCTTAATGTTCCGGATGGGCTCAGCTTCCTGAGGGAGGAGACGGCCTGAGCACCAGGTCCGGTCCGGGGTGAGGATCCCAGGAGGC
+
FB*@BAIAIBBB?I0BAAGIE?>BDHICHI?GEHIAC?B@BBF?@IGDB+C@BHCAC#ACAEAFFFE?AA%II?FC@DI!0BBEBFCD@HCB?@GDG?CG
@>chr21:9910482-9910580-2
GAAGGTCCTCAGCTCCTTAATGTTCCGGATGGGCTCAGCTTCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAAGAGCN
+
EFG?EAGEHBG?@BDBGB@DFGIC?BHHDIEGBG?CIBFHAEEGBGDE??FGHC?H?I@DCDAGH@BH@DBDAGGA@B@IEDEFI??@?ICIFD(?@I01
@>chr21:9910482-9910580-3
GAAGGTCCTCAGCTGGGCCTCCTCGGATCCTCACCAAGGACAGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGAAGCTGAGCCAATCCGGAACATTAA
+
DDIFCCEBGIIIGAIAE?BBFD@3DEB?GG?@DFBECFDD?-AA@GG@HDF?GDFHEIBIDGIA?BBAHIDDHIDFBEBAADEBG,AD@ABCIEIDFAHA
@>chr21:9910482-9910580-4
GAAAGTCCTCAGCTGGGCCCCCTGGGATCCTCACCGAGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGCAGCTGAGCCAATCCGGAACATTAA
+
HE?-@DBHHC?CFEF@@ID)I?DFEHIHGHIE?@A(IBIHB?D??HAHFI??AEBDIACBCCEDID@BDFA@C@BHI?FGC??AC>@CGGDBGEGICFGA
@>chr21:9910482-9910580-5
GAAGGTCCTCAGCTGGGCCTCCTGGGATCCTCACCAAGGACCGAATCTGGTGCTCAGTGCGTCTCCTCCCTCAGGCAGCTGAGCCCATCCAGAACATTAA
+
GFHCGDCBD?@HB@HCEIE??@EBBHDG?FAHE?DA?FCB@CB:GHAHIGBBBE@B?:CFEB?HADE?CGC@ECGFGIIIHDHBEIBAIA-DEH?ED@?G
@>chr21:9910482-9910580-0
GCGGCGTACAGCTCGTTAATGTTCCGGATGGGCTCAGCTTCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAGGCC
+
E@BCGHG@ID@@?I5@C?FF?IBCIHBC?HHI@GEI@HCCFF@GFECGIF??CDIHCHBDDBG@D@IIHGFHFIEIDGIGI?CHGADIFHAB?H@CGH@@
@>chr21:9910482-9910580-1
GCGGCGTACAGCTCCTTAATGTTCCGGATGGGCTCAGCTTCCTGAGGGAGGAGAAGCCCNGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAGGCC
+
ICD?E?EEEGIGECIDBIIAFHDGEG@IAEIHEDGEIGCFB?HHC?F@HH?D?@8AABG$IEE?@G@EDDB?D?C"HECIFGHA@HADHIEAGCII?FDA
@>chr21:9910482-9910580-2
GCGGCGTACAGCTCCTTAATGTTCCGGATGGGCTCAGTTTCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGAGGCC
+
CDF@?@@GEAF?C>HEAID?EGGAIBAFAFFFHFD@@5F@GI@IHDHAHH@HEAA?@DCBEFH@GB?EBC?@GFDB@C@?@IAD@GHFED?CIH???I@F
@>chr21:9910482-9910580-3
GCGGCGTACAGCTGGGCCTCCTGGGATCCTCACCAAGGACCGGAACTGATGCTCAGGGCGTCTCCTCCCTCAGGAAGCTGNGCCCATCCGGAACATTAAG
+
CIAH@IIGBGFEBHAEGDBBHIHFHBIB?AC?I@DH?IBGBFFD7?FC)I@GAFCFCF?DBBBAAGACBACH@FGCABFI!DDCFIEBED?CDBDBAHEB
@>chr21:9910482-9910580-4
GCGGCGTACAGCTGGGCCTCCTGGGATCCTCACGAAGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGAAGCTGAGCCCATCCGGAACATTAAG
+
IE@CEEDEAHB?IGGBHCG?GAA@CBIGC?IG?"DDE@DB@E@FCAADAACBCHCBGEFC@HHHBHIHIFCGIAGG?B?@FF@CHDEGIHG@BI?DBGDF
@>chr21:9910482-9910580-5
GCGGCGTACAGCTGGGCCCCCTGGGATCCTCACCAAGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGAAGCTGAGCCCATCCGGAACATTAAG
+
HFBFGGFGGFHDFHCEI?&@BEACE@IFHHGFHBG?@HCGBABEFAAC@EEACAG?EIBCCEBFAIAGBHCF@DCHAFIEBGDH@?BCIFEBCIEDC?CD
@>chr21:9910482-9910580-0
TCAGACGGTAATCAGCTCCTTAATGTTCCGGATGGGCTCAGCTGCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGA
+
IDBI@FE@?GDAE?D?GGBF??BIEEHG?@?@F@IACGHIADCHF@CF@GBGCEDHHAI@?GHA@?GGCBFEFIEIHCBDDGHBEDBCA?@FFAAEEFGG
@>chr21:9910482-9910580-1
TCAGACGGTACTCAGCTCGTTAATGTTCCGGATGGGCTCAGCTGCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGA
+
A??ICBD?GH2IFH??HD9BHDFGCAF?IHEBA@@GF?ADDCEIFCDBFGIBIHAGICFID@@?FGGIBCHHAIHGIECID@HFDCEHDA@DGFFCB?DI
@>chr21:9910482-9910580-2
TCAGACGGTAATCAGCTCCNTAATGTTCCGGATGGGCTCAGCTGCCTGAGGGAGGAGACGCCCTGAGCACCAGATCCGGTCCTTGGTGAGGATCCCAGGA
+
DIDID@.GHHEHEHCI@HB-@FDFI@@HCD?GGBEACGBCGHDHHICCH@DCGA@HDIG@IHAFEEEEHAFIGDGCBCFIGCBACDC?DIGHGG@ADAB@
@>chr21:9910482-9910580-3
TCAGACGGTAATCAGCTGGNCCTCCTGGNATCCTCACCAAGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGCAGCTGAGCCCATCCGGAACAT
+
GFH?FAGE?GIBIDICDCH%EGIA@EAE5IG?EHHFCHHGBA?I<?@GD?@BHF@AACB@AGFE@GCAEI?AB?EHDDI@FH@BEBF@IEA@@DBBGA?F
@>chr21:9910482-9910580-4
TCAGACGGTAATCAGCTGGGCCTCCTGGGATCCTCACCATGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGCAGCTGAGCCCATCCGGAACAT
+
@EGIFAE?GGC?@AHF?@@DIGDCF?DHB?AG?GGA@BE2?I@AIFDFCDA@??EEHEFHB@A?CGI@AB@FCH?FBHGBBHDAGGADIHAGFC?FA?@C
@>chr21:9910482-9910580-5
TCAGACGGTAATCAGCTGGGCCTCCTGGGATCCTCACCAAGGACCGGATCTGGTGCTCAGGGCGTCTCCTCCCTCAGGCAGCTGAGCCCATCCGGAACAT
+
?GA??F?AFCGBCADIA@EHI?IDCADFFBDI??FIFHBD7FCDFDIEH@G?A?CCBGFAF??GICFCFCEFCEEEDCAHIBBAIIGGCIECG+IIB?EH
@>chr21:9910577-9910745-0
ACCACTATGTCTGCTGAAGGCCTTGGTCAACACCCGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACTG
+
FEC?@I?FDCIAIIHDF?A?EI??AB?IBFACDB$A@AADGA?@@DIICE?HIDIICCI??IC@@D?BECH?FHEBAIG@HFDGFIADAHGDDEHGC?DC
@>chr21:9910577-9910745-1
ACCACTATGTCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACTG
+
ID@DCE@BH@D@GFFHHI@HFGHBDH?@??G@HIGB?CBGI?GBCA@DGB?HGBGCEEECIHAGBIEG?AGH?D?EF?GD?BFFC?@GF?FE@D@BCAFA
@>chr21:9910577-9910745-2
ACCACTATGTCTGCTGAAGGCCTTGGTCAACANCTGAGCAACCAGAAATAATTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACTG
+
AC?H?AGGGEDGC?DIFEH?GIABEDEBIIB@"H@@?HFGDDEICGFFDD*CBGBE2EBCD@@GACIH@E??BHBDB@DBA@GIFDGHAEGGAHIH?IH?
@>chr21:9910577-9910745-3
ACCACTATGTCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGGACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGAGC
+
IICEFBEEAFIB?@@GFDADBDBAAHDEI?AGEHCCAE?IFH@GF??A?DIEE@HCDHBHFBHAGFEECD@DI@*AD?F@DHIGAFG,GGIA@HEGFCIF
@>chr21:9910577-9910745-4
ACCACTATGTCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGGACCAAGGAGACTGCCCAAAAGCCCAGGATAAACCCAGTGAGAGAGC
+
D@DCF@@GBD?DD@AFC?ECDB@DB@?HHE@ACBC@CFIFFIBAFICEAG@DEHC?BFEDH?GI/GBDCCFFCEDECDCCGAGD?EB@HGBFHA?HGHGA
@>chr21:9910577-9910745-5
ACCACTATGTCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGGACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGAGC
+
CIGGIBCIIHBA@A?FCIBFEIIHA4@HACC?BHCBIDHGCEHEGE?FFHECCDFDD@F????EE?@GCBBD?@HBAGGHA@ECH?@DD@B@DBA@@CDI
@>chr21:9910577-9910745-0
CTCATACTACGCTGCTGAAGGCCTTGGNCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGATCTCTGACTGTGCAAGATCCGCTGTCTCACT
+
ECBFIBC&AE@E?HHCDEIEEIB?FBG"FFBHAGFI?ECCGDEFIFFGE?FBHB?EBFDIF?A/EIBHI*FB6EDE@DFIEDC@G+BI-?EA>IDC?IEG
@>chr21:9910577-9910745-1
CGCATACTACGCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACT
+
A6@F@C@$BBCHC@ACIC?BF@BDHEH@?BBI@EFE?BFHEIB?HCCCDIFIHCAAEFCCEEBGAA?CGIG??@?FAHCA??@HE?EAF?BB?EFBGF@H
@>chr21:9910577-9910745-2
CTCATACCACGCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAGTGCCGGGCCTGAGCTCTGACTGTGCAAGNTCTGCTCTCTCACT
+
D?@?D?AIBHAECGBAIADCF@EDD@I@?@BICAFHCBFDCIBI@F=@IEHH??I?(BFHI?G@??IFEIHDCG?BE@BBBHGDI;BBGE@GD@GHGGGB
@>chr21:9910577-9910745-3
CTCATACCACGCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGCACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGAG
+
FDH?GFEHBFHDC@A?I?A??BBI?HIIHGH@BIFBHGFBFIAIBHG?@AE@BG?AADEGAHA@HFBGBHCCHEDFHIGI@EBDHDDIIGIEADFF??IA
@>chr21:9910577-9910745-4
CTTATACCACGCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGCACCAAGGAGAATGCCCAAAAGCCCAGGATATACCCAGTGGGAGAG
+
FI'GIIA@AIHDBCECEACEDBDEHFAAGCHFFGFECA@DEDHIIBADH@AGH?FBE@?EGDE@FIHFDADBDDEGAICI@?HAE3DA?G@FGI,EAIAG
@>chr21:9910577-9910745-5
CTCATACCACGCAGCCCATAGAAAGCCCTTGAGGAAAACAACCCACTTACAATGCACCTAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGCGAA
+
EDBD?BHAADIEB@AHGH@?A@B>FADBGCIBF@IGFIFEGCA@GBD@HDDI@BBBC?=FEBDGBGDDDAHCG@@DFIIDH?@HCHBAIAE?AH?F1F@2
@>chr21:9910577-9910745-0
GAAGGTCCTCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACTGG
+
BGFBA?HAE?G@DHAEGACBBHGEBEBCH?BHGBAABBDAG@?C?CDBCDFIEIF?HCHBI@@AECF#IFEGEACIAHBDHBDECI@AGCD@DIGC??FC
@>chr21:9910577-9910745-1
GAAGGTCCTCTTCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTAACTGTGCAAGTTCTGCTCTCTCACTGG
+
HD?EF?FBDEI#IDF@@BEI?CHBGGCABBCA??FF??BCHAI?ABBAHIEH?DFAHBGBABBB@?IHB??G2EBI@@DIHAEH?C@AIIAC@?@@HHDB
@>chr21:9910577-9910745-2
GAAGGTCCTCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGTCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACTGG
+
GCEF@HFACCI@BHAFD?EEA@FCBIEFHGGHA@AGGFDABIDDFCGEICCHF@GDBBGD@B:HFDF@HE@ICAHBFBFAB?HEHIDAEAF?CCCC@DHB
@>chr21:9910577-9910745-3
GAAGGTCCTCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGGACCAAGGAGAACGCCCATAAGCCCAGGATAAAACCAGTGAGAGAGCC
+
H?FC@HBADB?IBEFB@IBEI@ICGD@DIBBGDB@I?DCDGEBH@@DD@C@FIAB?IGADFF?F=@ABHA5EHFG?BHC?GDII@#BHDEAG?ICGB@E3
@>chr21:9910577-9910745-4
GAAGGTCCTCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGGACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGAGTA
+
IEA@GEIGCHEEIEFICCHBGIFBF?IIA?CABCHHED@EFB@HDCAFFD?CH@FDA?CIFB?HAADGFCFE?G@GHCBGED@GEHEDDDAIIEAGCG+D
@>chr21:9910577-9910745-5
GAAGGNCCTCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTCACAATGGACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGAGCA
+
ACD@D&AEAACIFHFFG?DIGG?@@HACGHGDDIFCHBFGGHA@G5CBA?DHACGFBEDHHBEDFICE@IAFADECB?IA@HFBBDC@HHIAE@AG??AB
@>chr21:9910577-9910745-0
GCGGCGTACTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACTGGG
+
EADCBG?DI?IHAIC?EHIFIE@DEHBFF?@IFD@@?AAFD@CB?H@FHBEH?CBF??FBBIFFBCHBHEDBDIAGGGHECEHIA?I@HE.EAF@@GHHD
@>chr21:9910577-9910745-1
GCGGCGTACTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCACTGGG
+
I@GBGGFII?E?ABEII@@HBABDBC@@AICHIGHG?AADFBIFCD?CBFA@ADHD?CGAHCIG@IFGEB?HE@@ADBBC?CEF?@AGHAA?FHE@AGAH
@>chr21:9910577-9910745-2
GCGGCGTACTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGGTGTATGCCGGGCCTGAGCACTGACTGTGCAAGTTCTGCTCTCTCACTGGG
+
H@HHAEBEDEFB?DHF@GD?CH?FGFI?DI?EBFFBHDEBEICDF?A?A!IA7IE@?D@BI?D@GF@D'GCEE@FFBFCCED@?BH?GDFHIGHC@EII?
@>chr21:9910577-9910745-3
GCGGCGTACAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGCACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGAGCAG
+
?IFEEHIAHHEIEGD?@DGBB?IBFIC?CEE@FHBDF@@AHD?A@DEBHHCH?ICBE?IGIGHFFECD@C@I?FHCADC?FD@BCBGADD@GCEHH@HIG
@>chr21:9910577-9910745-4
GCGGCGTACAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGGACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGGGCAG
+
FAIEECBDED@F@?IICDD?AH??BFHICIDGCBHGFB?FCDA@@GGDCBI?ACDEA@FIH?HBGCID?I?D?CGHCC?CI?B?ADH?AHC?HFF(IHIB
@>chr21:9910577-9910745-5
GCGGCGTACAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGGACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGGGAGAGAGCAG
+
DDEFGCH@AFAFIE+IECEIHAHGEEIHDHDEAGDGAEFI?FH?IG?@IB?AG?GBHAEI@BHG@EGACHG@ACGEBHDBEFCGF@IHD>D?GGFGBDEA
@>chr21:9910577-9910745-0
TCAGACGGTAATCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCGCTGACTGTGCAAGTTCTGCTCTCTCAC
+
IBAFGHGE?DCBD@GDE@GH@AFG@EIFIBCI@BCDFDGAIIDHAAA?BCIGAFBHEF?IEDIEGHGA?CFC5G@IGCIGF?@CCC??FA@DHGGIAEDC
@>chr21:9910577-9910745-1
TCAGACGGTAATCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTCTCAC
+
@?B??BGAEIFBDGB@ADDFCC@GADGEBBBADDAIGCDICA@A?FI@BHCIFH@DAB7@BAICHGHEDE?@@B@BGBFHDI@DECGBFCBAIEDIDGGI
@>chr21:9910577-9910745-2
TCAGACGGTAATCTGCTGAAGGCCTTGGTCAACACCTGAGCAACCAGAAATAGTTGAATGCCGGGCCTGAGCTCTGACTGTGCAAGTTCTGCTCTATCAC
+
EEI?C@HBE?CHIEHDI@EDC?@GDEEIIIIDCGDI?FH?IGE?FC?GADHDIDABF?D?GFB@GFBDEFGA@DECHFAGIIHIFG@CBI?F@EC+HEGA
@>chr21:9910577-9910745-3
TCAGACGGTAATCAGCCCATAGAAGGCGCTTGAGGAAAACAACCCACTTACAATGCACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGANA
+
ACCIDEADF@D?H@@DAAEFDDBGIEE#ACICF@?CBCEH@BCE@@FCC@DBH?HHA?CECFIF@?G@EBFABIBGDBEBAE@I@@IB?DIHEB?AHG,D
@>chr21:9910577-9910745-4
TCAGATGCTAATCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTATAATGCACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGA
+
BAE?E,D:F@?@AAEFICA@AEG?FIGGCH@@FAIH@FECEFBDHCAEDI9E?FADGBHCH?CFH@BFCE?FIBIHBCIE@?DCBECE?EABHCHBHDC@
@>chr21:9910577-9910745-5
TCAGACGGTAATCAGCCCATAGAAGGCCCTTGAGGAAAACAACCCACTTACAATGCACCAAGGAGAATGCCCAAAAGCCCAGGATAAACCCAGTGAGAGA
+
?@ICDAHEEDDAAEDCCC@AFDEFH@AFEDHBIFID@BCF@CIGGAEH@DHB?A@BB@GB?@G@@GHEFICAAFCBBB@BCBAAG@@BC?I?GBEIEH?A
@>chr21:9910742-9910804-0
ACCACTATGTCTGCTGGGAAGGTCCCTTAGTCGCAGTTCCTACGCCCCAGTCCTCAAGAGTCATCACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
FIGCGIAFDACC@G@IFIDIFHADEG@CA@D4I?FBBDEH7ADIHCFEDG(CHIAGCI@@BIEDGBI?FHDEEAGHCI??EBBFBCFFIACIFH@?DA5H
@>chr21:9910742-9910804-1
ACCACTATGTCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAAGAGTCATCACTGCTGAGATCGGCAGAGCGAAAAAAAAAAAAAA
+
?EH?IDFFCBEB@IEI@@EB@IAHFFFFCF?GHAIHDIBCC@CBFH?FHCEGG?B?IG?@FBD@?E@AFD?HFGBE@HB<EFFGCHCGC@EFBFHA@CEB
@>chr21:9910742-9910804-2
ACCACTATGTCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAAGAGTCATCACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
ABG@EAEA?@GIEDDBADHGAADDCAGH?IEEDIFDFC?BG??BIAEHGAB@ACE@B?H@?A?@IEIAB??BCAFBBHBEHGHCG?EHGAABACCEDDCD
@>chr21:9910742-9910804-3
GCCACTATGTCAGCAGTGATGACTCTTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCATAGATCGGAAGAGCGAAAAAAAAAAAAAA
+
0IIAD@DIDIEGAAC?IFCFBB?BGFCGHIFC?AHIBBDDIBD?I@AEHIFFDCADFF?B?FFEIAH?CII7BAGC@I?GEBDC@@B?DBFA??ACI?IF
@>chr21:9910742-9910804-4
ACCACTATGTCAGCAGTGATGACTCTAGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAATAAAAA
+
IIBE@@CCCI@IEE@?FD.DF@A@C?;GEHFDA?D@FHHA@FB@@AGC?AAB?CFFBBEBAC?BFHF?A?IGCFB?E?BCHHA?H@CEBBEDBF8EC?G?
@>chr21:9910742-9910804-5
ACCACTATGTCAGCAGTGATGACTCTTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGANATCGGAAGAGCGAATAAAAAAAAAAA
+
BGCAF?CAFGEH@E@GAAD>@HHBHD?EACIAA@EGC?B@@?EADFF@@EADA?BIC@GHGABHG?DHCHGEB-GFID?I?GHDA@G?!A??ACHEFEBF
@>chr21:9910742-9910804-0
CTCATACCACGCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAATAGTCATCACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
H?G@DFBACBHG@ABDC?HFFEG?DG?EICCBB@G@DFEFHE?IFCG?I?@BB?B6EA?CHEEFBIED@G?IDBC?@??FCIBB?B@?AAAHBBG@BCHC
@>chr21:9910742-9910804-1
CTCATACCACGCTGCTGGGACGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAAGAGTCATCACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
BGDCG?EGHAI@CAD@EGFG)BGDEC@CGHH?DI@=C@HF@EFBBH@DGEHIHDACEGAHB?C?DE@FFAFBBAHFGG@F@?BGAFFB?EDEFEF<?HI@
@>chr21:9910742-9910804-2
CTCATACCACGCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCNAGGCCTCAAGAGTCATCACTNCTAAGATCGGAAGAGCGAAAAAAAAAAAAA
+
FFGHB@GHAFB?IEIFI@C??DFF?BHGC@D?BE2@FFG?DG?EAI@I3FCECBED$BBEEDFGFDHAA#ID(DHBHDDIEDCGDAIIFFAIHFBIAC?I
@>chr21:9910742-9910804-3
CTCNTACCACGCAGCAGTGATGACTCTTGAGGCGTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
IHD>IBCGFEDAC?GC@FC@C@ACD@AFA@@+G"IDCAIAHA@EHEDBBI@GGGDAC?IIFHFHEEGG@GAEBG?FBGGHE?EDFBA@GGCADAF@A@IE
@>chr21:9910742-9910804-4
CTCATACCACGCAGCAGTGATGACTATTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
AHFI@CH@GAE?BEC?D?DEGCCEDBCEBBA?DDDIGEFDD?FEGHIAFBCC@FE@C@H?@@E?EIGF@@IA?BEA@ECD?IGD?F@GBCFD@I?AF?A@
@>chr21:9910742-9910804-5
CTCATACCACGCAGCAGTGATGACTATTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAA
+
EHHCFDIEBIGCD??FA@AEICEABDG?DIAAIAEDCBA?DEF??DHHBFAFFI@GFDCI@?DG?GEEC?IEC@CE@EAFH@G?FG@DGBIEAAEG??CB
@>chr21:9910742-9910804-0
GAAGGTCCTCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAATAGTCATCACTGCTGAGATCGGANGAGCGAAAAAAAAAAAAAAA
+
GGIAD@DCBFHFBBFCGDADIAB?EG@BIEI@?AFIIEB?HHFGF?@F?FFEFDCIAHEEIDC@?FFIHCGGB?@DDA@8F??IAEACAID?D?EFD?DE
@>chr21:9910742-9910804-1
GAAGGTCCTCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAATAGTCATCACTGCTGAGATCGGCAGAGCGAAAAAAAAAAAAGAA
+
FHEECIH@EGFGFDFCACFDICFEFGCEICBBEB?HEBFGIFB?CEA@IFCG?HBA@CGAEH@CEEBBHEGBAABEA?>@FBH@IECIH@FBFBCEI%CA
@>chr21:9910742-9910804-2
GAAGGTCCTCTGCTGGGAANGTCCCTTAGTGGCAGTTCCAACGCCCCGGGCCTCAATAGTCATCACTGCTAAGATCGGCAGAGCGAAAAAAAAAAAAAAA
+
@ABFDHEGHFGIE@FIDAH3GFCF@A@ECEGDACCHAAG$?HHIFHI&DGD?GIBFC@DEB@IAGBEEIF0FICHBCF,GEFCDD?GCC@@IBHICGFEH
@>chr21:9910742-9910804-3
TCAGGTCCTCAGCAGTGATGACTATTGAGGCCTGGGGCGTTGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAACA
+
(6DDCEIHACACBHDDI?A@@CEGG@DFFHDBFBAEFEFG/GBHE?F@F?EB@ECCCBHBHAHD@FCAHGFHH?HED?@GIIEBD?GCAAEHIIEFDB+D
@>chr21:9910742-9910804-4
GAAGGTCCTCAGCAGTGATGACTATTGAGGCCTGGGGCGNGGGAACTNCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
@DD@?@BEFIDG?GI?DF?GB@GH@@E???C@?DCEDEC2EGIFH?A-BDEBGICBFBAFEAD?ICFDBFFCDCCGEDHAEAICCFGFBBEACIACAGAC
@>chr21:9910742-9910804-5
GAAGGTCCTCAGCAGTGATGACTATTGAGGCCTGGGGCGTGGGAACTGCCACTAACGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAA
+
C@BAFDGB@@GEB@GFCFIH@FDBDABD?@CII@GFBEIAAIAD@GDFB@H@E?G!?DHFEFA@AHGIICGAFDCB@A?G@?FCEDCFG?DGFHCBGF@G
@>chr21:9910742-9910804-0
GCGGCGTACTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAAGAGTCATCACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
IIADGIB@IGI@DAAABAHHDICCF?FCIHFDEE?FH@IEG@C?C@BDIGHDFHABFGDH?BBBFBDGDEBGHIIIHADIF?@C??HEEIDHBICD?D?B
@>chr21:9910742-9910804-1
GCGGCGTACTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGTCCTCAAGAGTCATCACTGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
?H@GHCD?EBHDH@@EBBEGAAFEIGB?@EFGFE@?BC?ADBACC@CG0HFC@BIEGIGIGDG@?G@@@AHD@?FFG?G?G?AIE@H@?FCC@FAEFDAF
@>chr21:9910742-9910804-2
GCGGCGTACTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCGAGGCCTCAAGAGTCATCACTGCTGAGATCGGAAGAGCNAAAAAAAAAAAAAAAA
+
GDGG@I??EHHGHGBBIDFF??IGADFGIGH?I@B?CEHFHI@HE"@IHBFDE@FAGAGEEFCEFBB@@EBAAGCACFCFGC@3@E@HHDHIIA@HBCFE
@>chr21:9910742-9910804-3
GCGGCGTACAGCAGTGATGACTCTTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
?DEAII?HC@EIDC@DC@CGCCC@EHC?BABCDD@-=EC??EGHBBEFFBAAF@EGFFGABIEC?E?HGCIC@DHFI@ECDHII?B?CHEHGFABBIGGF
@>chr21:9910742-9910804-4
GCTGCGTACAGCAGTGATGACTCTTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
IC9IBAGGA?IGHCCCEE?@C@?FEDHH@EB?@GEFICBIAB?GGBD?FEB@I@CHAEIGBGAAF@EDAD?IIIIGABICBGA?FAHDGC@ACAC?H@BF
@>chr21:9910742-9910804-5
GNGGCGTACAGCAGTGATGACTCTTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAAAAAA
+
H-B?AGEDEC@GDDF@CEFEHCBA?GBH?GEIEIHH@CCBEGHAFGAB?HHAIHBID?FAEGECFCIBDCHDHDFD?EDG@@H?A?EGDHCDEI?DECAE
@>chr21:9910742-9910804-0
TCAGACGGTAATCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAATAGTCATCACTTCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
BAEHCFHEAFH?FGI@ED?DBIIDACB?HCBDA?A@IEH?EGHDBCEBIF?A?ECDIDF?@IBBBCGCAA8@B?@GDI@BE?BAG?GEIBF@DAD?HEIF
@>chr21:9910742-9910804-1
TCAGACGGTAATCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAAGAGTCATCTCTGCTGAGATCGGAAGAGCGAAAAAAAAAAAA
+
ADB@DIEIAH@IICHH@HHIG@H@HBBHCICB@@IEI@CFAAEAD@HCHF?EGIGCEFDDBBIEBIF.EF??HDADIABFBEH?EDGHACDDCHGFBI?I
@>chr21:9910742-9910804-2
TCAGACGGTAATCTGCTGGGAAGGTCCCTTAGTGGCAGTTCCCACGCCCCAGGCCTCAAGACTCATCACTGCTGAGACCGGAAGAGCGAAAAAAAAAAAA
+
IFIABBACE@IFEFEICGFCHB@BDIDHBG@HEFA?@CDI?@@7?CEDF?IGBBGDCI?EB,ADDBGBD@@AGBD@F9EHCB?DEC@@DBICB@@?HBCD
@>chr21:9910742-9910804-3
TCAGACGGTAATCAGCAGTGATGACTCTTGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTGCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
DDI@FDCC?AEEDDFGEED@@@CEF?IDGBBGIC@?IEAGFA@A?HD@BCAAFAAH@E?HIA@CI!HH@HFA?FDC@FIIECFEAC???@HDBC?FBI@E
@>chr21:9910742-9910804-4
TCAGACGGTAATCAGCAGTGATGACTATTGAGGCCTGGGGCGTGGGCACTTCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
AFDBEHCGECD@BIFIDIBAHGEE?CIGICDEHCIGCB?GCHCCA?8CDG+@G?EEFH?H@AGCBA?BEHFGGEHGACEECCAFHCDDFCFH?FEHACHE
@>chr21:9910742-9910804-5
TCAGAAGGTAATCAGCAGTGATGACTNTNGAGGCCTGGGGCGTGGGAACTGCCACTAAGGGACCTTCCCAGCAGAGATCGGAAGAGCGAAAAAAAAAAAA
+
DAI?D+HCB?FHHC?@@G?GIEHB@E3G8AE@A?DEADFDDG?CADA?D@ECA@AEHGCEHFADGDDAE?@BEFFC@BEGC@HB?HH?ABBIBAIH@DDD
@>chr21:9910801-9910899-0
ACCACTATGTCTGCTCACTCAGTGCAACCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGAGCCAAACTCTGGGGGCCCAGATGCCCGC
+
HFAGEA?IFBGD@AID?CG?@AG@?G!?HE?AHD?E@FGADIC@BE@HH?DEEIA?FAAGB2AGCFCE?@@H:@BEEDDHCHDG?ABGCBDFCFE@DFHA
@>chr21:9910801-9910899-1
ACCACTATGTCCGCTCACTCAGTGCACCCAGGAACGTTGGCTTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCCGC
+
EGIGECCB@AG9HA@BF?DHCHCFEBA??ED<BCDAH@IBI6@IHC@EA?FBHC@?D@D??GG?DBDBCCC@G??EG@ICCFFFGAB@I@CD@A@BBDEC
@>chr21:9910801-9910899-2
ACCACTATGTCTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCGAAACTCTGGGGGCCCAGATGCCCGC
+
D@GDCB?@?B?@IG@E?@IABCBGG@IADIGBDIGGFEG?@FDCAABHGC@HBCI@AGCFCGIE@DB@HFCG?I-GHBF?AEID@HDAB@BEB@CACIBI
@>chr21:9910801-9910899-3
ACCACTATGTCTGCCCGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCACTGA
+
?BI@@I?GCAFI@DH.C?@BIAAAAIHG?BIHBGBEAGBADCCBC?@HDEDH@BDFA?EHDIDEFCCEAIHI??BGIF@GECGAHGIHCGDEG?FF?DHC
@>chr21:9910801-9910899-4
ACCACTATGTTTGCCTGGGCGCGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAAGGGCAGGCCAACGTTCCTGGGTGCACTGA
+
?BICHCFDFF<FGHDH@BFC@9CH?@ABFEHAAEAC??DD@@BHGGCIDCIGHEHAGFAHDHIEI@BBB@3CIIBGHCBFI?@C7?IIFCDEB?AHHBBC
@>chr21:9910801-9910899-5
ACCACTATGTCTGCCTGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTTCTTGGGTGCACTGA
+
@BIDCBIIIBE@G?EEDD?@BFE@B@BIHEGA@HHFCDGIBIDIFGCDA?@CEDI@CEIFC;HEBDFIAD?@GHCIDGAABGHDF@I/HCGIBBBGG?CE
@>chr21:9910801-9910899-0
CTCATACCACGCTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGNCAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCCG
+
DH@@FBDHEF@AA?%EFHB?EGDB@ECGEBHDCBDEGDD?I?EFA?@@DDBDIIG@DDG<DCIHCEE?EBIHGDHDBBB?BFGA@AIB?E?AGBADCE?B
@>chr21:9910801-9910899-1
CTCATACCACGCTGCTCACACAGTGCACCCAGGAACGTTGGCTTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCCG
+
DEDDGE@?A@BDDHFB@FI,BEFB?ABI@BFC@?CAHB??HG#HDDCCFGFAHAEE??GB??ADIA?IHCBGIFFAB@@@?GIGI?GG?IG@EAGIIABI
@>chr21:9910801-9910899-2
CTCATACCACGCTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCANATGCCCG
+
A@CFFGC?HIADH@EIBD@AH?BGGHFIEECCBCEDEDHGH?HAFFHF@HCF?C?BEB@AAE@G@AHEIIBBAADBIF@I@EDH?FID?DG@+CFGBH@F
@>chr21:9910801-9910899-3
CTCATACCACGCAGCCTGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGNGGCAGGCCAACGTTCCTGGGTGCACTG
+
AFEGBFDIF?AGHD@@IDIBDBGF?E?@IIHHFEEGADC@AGAEC@HBIHG@AFEIIBCACCABBGIIAGAC&GCAIEAC?FDHAG?A?ICIHGFIFDDC
@>chr21:9910801-9910899-4
CTCATACCACGCAGCCTGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGGCCAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCACTG
+
?GBHH?@HHHHGG@C??CHIIAIAB?ECC?DEEGGCD@@E@AEAHE?CFI?@?FHHDABF>A?CE?DFIBFGCEGGBDDEG@FGFC@EIIDDEHBCHCBI
@>chr21:9910801-9910899-5
CTCANACCACGCAGCCTGGGTGGACATCTGGACCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTGCCTGGNTGCACTG
+
BBG@&HIDAEG@GFHDGCGB"?H;BD@AEAH,DAF?@CIBECGHDIACEEHBIDIFEHGDH@E@I@BHH??@A?HFEDG?GH?H@E4?@EDE#@DA?ABF
@>chr21:9910801-9910899-0
GAAGGTCCTCTGCTCACTCAGTGCACCCAGGAACGTTGGCGTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCCGCC
+
GBDBA@F?DAIAI@DFDEC?EGBI?ED@CCF?@AGCGBDG,IAHDIFG@D?BAC??DHI@AEIH@@BCC?EHB@?EGF@HEIEFCADH?CIGBACG?H??
@>chr21:9910801-9910899-1
GAAGGTCCTCTGCTCACTCGGTGCACCCAGGAACGTTAGCCTGCCCCTGGCCTCTGGACNGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCCGCC
+
ED@??GCIFG@ECDCE@EH0FH?F@HIECFIEGFIBG%?HA(IFD@AAGA?EHGFBFEH/@ECIABFE?IFADBHHHGIGGDEIBABDBDEAIIFHHEAH
@>chr21:9910801-9910899-2
TAAGGTCCTCTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCAAAACACTGGGGGCCCAGATGCCCGCC
+
+HBCBHAHII?BGE?AGCDI?H@?HFH?DFFGAD?FID?HCHDA?HBI?AH@A@HAHGFGGHE?CEDD??CEH+HECE$FD@ED?FIICHHC??BEI?CI
@>chr21:9910801-9910899-3
GAAGGTCCTCAGCCTGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTACAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCACTGAG
+
AFIAIDDCFIA?CGBDAEFDBF?@?AC@GIAFFHADE@CGFDF?IEDFA?DHH@BEGFE#DICGBHGIBEHACEIF@GBFEDGH@IACA?DBG?FCHEH@
@>chr21:9910801-9910899-4
GAAGGTCCTCTGCCTGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCACTGAG
+
A@IADABDA@6@FF@@H?@CACACDGH@IA@EIBIAAFEABHAIABHFIB@G?HGD?GFAGH@BDGDIAC?GBDCFI?@GCGI?)=CBDFEI@D?ADCHG
@>chr21:9910801-9910899-5
GAAGGTCCTCAGCCTGGGCGGGCNTCTGGGCCCCCAGAGTTTGGGTCCTCTGGGGCTGTCCAGAGGCCCGGGGCAGGCCAACGTTCCTGGGTGCACTGAN
+
B?G?GFCCHAGA?FEDC@HHEIC6A@IGE?BBFAHHGEIAI@?CF?IFAG&DFHEDA@BF@EI@IACF%?I?GDE@HDGEFEGIFACIIAHDE@A?AEG"
@>chr21:9910801-9910899-0
GCGGCGTACTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCCGCCC
+
?AAB@BGIIH??EGIIB@FIFHD@FDICIBDHCH@GG@@EAGHB?CCA?GG@GAEBEH?@E?H?EA?@HIIEH?ICC?ECHF?GIHFFEFF@I?I@FAFF
@>chr21:9910801-9910899-1
GCGGCGTACTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCCCTGGTCAACCCCCGAGGAACCAAACTCTGGGGGCCCAGATGCCCGCCC
+
?IDIEIFHG@?@?CFGAEC@CGDG@?C?ABEGICAHGIB@@EEDAI@EHEH0B?EC.ID7AAE@GEIBB6,ED@BG?I?GGHCECEB@BGIFG@ACBC@?
@>chr21:9910801-9910899-2
GCGGCGTACTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCCGCCC
+
HH@DAHGC@B?AI@ED@CE?BCCCC@FFEICCBCBI?E@DD?HCEID@CC?DEEIIAB@HAEHFADEGAGFFGHDIGIE?D@HCHB@?@DHHIHIBF@FH
@>chr21:9910801-9910899-3
GCGGCGTACAGCCTGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCANTGAGT
+
ABDFBDEEDHEA@DHHEC@?EGHFCCCBBB@D?H?DDIIC@@BGC?FD?HDIII?BDAF?G?FH@@@EDFE?EGDCFF?FBFH?@AIG?BFG@D:IC?CB
@>chr21:9910801-9910899-4
GCGGCGTACTGCCTGGGCGGGCATCTGGGCCCCCAGAGTATGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCACTGAGT
+
BGC?BCCFD??GCC?C?DC@?DCB@CBBG@FFEDGAEGF,DBE?GIFHBGA@?@HGGGICBBF@GBD@B@C?@GGDGFCEGF?@B@FHEIEAEGGEFID=
@>chr21:9910801-9910899-5
GCGGCGTACTGCCTGGGCGGGCAACTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGCTCCTCGGTGCACTGAGT
+
CB"HID?GEFA@EDBB?HE?DGI;IGIFEH??ACGGBFBDHAI@A@CFCA@CG?C@DCCDDDI?FFFB@BFBE@FC@@?F@A;DDEA7I@F@D?II@EFI
@>chr21:9910801-9910899-0
TCAGACGGTTATCTGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGCGGGCCCAGATGCCC
+
FFFCGIFFG:DEDFGCBFIEAHBA?BDECHFAHB@ICDEIFF@BGHAC?ACHAED?E@IAHEADCCHCCA?@GHECCIED@@HAG"HHEHA?CA@A@EFH
@>chr21:9910801-9910899-1
TCAGACGGTAATCTGCTCACTCAGTGCACCCAGGAACGTTTGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCC
+
????FHGA?BGG@D@CE?HC@IBHFAEC?E?@?HBG@FGB6ADI@FGHG@FF??BEHCEIAICGBAI?IBHCH??GH@AG?C@IDD@?HBIGFHHFIBGI
@>chr21:9910801-9910899-2
TCACACGGTAATATGCTCACTCAGTGCACCCAGGAACGTTGGCCTGCCCCTGGCCTCTGGACAGCCCCCGAGGACCCAAACTCTGGGGGCCCAGATGCCC
+
?@A*?AEE@I@C'@@CDFAHEACCCDBEIDAIAAHADACBHAF?EIEE?DGFHFHC@BFAIAGGAGEHBFEA@@@AHCBDBHHBDAEHAABF@F??HFDI
@>chr21:9910801-9910899-3
TCAGACGGTAATCAGCCTGGGCGGGCATCTGGGCCCCCAGGGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCACT
+
ADBF@DI?FHIAB?HBBAH@EF@AEA?@AFGBD?CCDHCH+CCEH?FDBGF?AD?@@FIFIF?IBHEHIF@AFB@AAC?BHHDFFDIHFEFC?FBB@GFC
@>chr21:9910801-9910899-4
TCAGACGGTAATCAGCCTGGGCGNGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAGGCCAACGTTCCTGGGTGCACT
+
ICFGBHBGGH?D?FI?EE@GDIE.@??C?DIEHFCAIIIE?FB@AGF?BCFBAE@B@EF?B?GBIHFBEC@??@DF?C?D?@BIA?B?GDDH@F?F@HGC
@>chr21:9910801-9910899-5
TCAGACGGTAATCAGTCTGGGCGGGCATCTGGGCCCCCAGAGTTTGGGTCCTCGGGGGCTGTCCAGAGGCCAGGGGCAAGCCAACGTTCCTGGGTGCACT
+
EBHCGADGGECBI?B=@?IABBG@GFHGFGAF@?@CHFICGHED@HEBG@CCAECDGCBEH@CEHEGFEBGHI@H?EE9CF?ICH@G?EEBBGHDHHBDA
@>chr21:9911176-9911317-0
ACCACTATGTCTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGAGATAGGCCTGCATAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGGA
+
BEA@DAGF?B@@IBEI@BF@?AFGEAB@HHIB?F@HHFFIE@?DBI!GBCGADFHDFGG5GHD?DEEAGEHFE@IC?B?EGAABGIEGGCGEF@HG@AFA
@>chr21:9911176-9911317-1
ACCACTATGTCTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGGA
+
I@CFA@@H?@IEI@BAHFIIHBIGGG?ICADEDFDC@@DI@BB?DHGHBGEBHBAFBGEA?GCCEHHDGFIEFAHIGGIADDBD@HAIG??FICHEBHBC
@>chr21:9911176-9911317-2
ACCACTATGTCTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAGGGGAGGGA
+
FHFAICI?BDH??GECA?A?FDIC?FC@BEFAHC??ICCGII?GICFEEA@AAHIECHHEBGBE@FHAA@E?C@HHDBH@GAHE@@@GCHB9@CG?EIGA
@>chr21:9911176-9911317-3
ACCACTATGTCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCGTCCCNTCATGCCTTCCCTCCTCCCTCCCTTCCCCT
+
BGHGFFIAGB@@CH@BIIAF?I@GDDA?CCGAGGHECBEC?I@DA@H?ADEAAAEGCBDHB?AA#HA?C7GG?DDBFEFHGIG@@@F?ACCCIHHCFIEI
@>chr21:9911176-9911317-4
ACCACTATGTCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCCTGAGTCCCTCCCTCCCTTCATGCCTCCCCTCCTCCCTCCCTTCCCCT
+
AACB?FB?CCDGBBBFBHHIAACCDIIECDB?@CGEBBIE@GE?GGIF@EBI>CECCIHDHBFCAGGII?DGICDCDC<EIEHDGHHDBBEH@CGHA?CH
@>chr21:9911176-9911317-5
ACCACTATGTCAGCTGGTNTCCNGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCCTCCCTTCATGCCTTCCCTCCTCCCTCCCTTCCCCT
+
@AH?EAICBFIIC?CEBD*I@D;G@?ICH@G?@AFCECAIHIHGIEAACHGC@HIE?ADI?EBFCHC?@DEFBF?EHEFIGH?A?@BEH?CF?HFBII?B
@>chr21:9911176-9911317-0
CTCATACCACGCTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGG
+
DCFDBDHIFAD@DEBAFGGBC?FFGDBDHGGCFIEECHF@ICACEHEAGF@FCGIGGBEG?DIGFAB@@GAFD?FFEEBBAHCEGCCACB?ADGGIAAAA
@>chr21:9911176-9911317-1
CTCATACCACGCTGCAGCAGTTCTTAAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGG
+
HD?#AGCIBAHAGIHIAI?AD?ACI*DBG@@DBGBCD@C@CDED@GF?@BFIEA?@DGGH?AC?DFDBEHCE?DBDADAFBCEDBFBFBEC?CAFIFBBC
@>chr21:9911176-9911317-2
CTCATACCACGCTGCAGCAGTTCTTGAGGCACTGAGAATGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGG
+
GDCB?FGH?FEBI?EF??GEDIFD@DFDIADC??FGDB<H?EGGD?HGEEGA??EFD@DG@?B?G@BGFFE@FC@??GHHDCEGHDCFFEFE@CEDGHAF
@>chr21:9911176-9911317-3
CTCATACCACGCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCGCCCTCCCTTCATGCCTTCCCTCCTCCCTCCCTTCCCC
+
EAIB@CCEHFA?AC@@CBFDG?C?IIBFCIHBEHBEI?GFHA@BCGDGIHBB?CF??BDEFA#ADE@GHH@EBCHIIHGIDACGDGBDGBC@E?GB?GBD
@>chr21:9911176-9911317-4
CTCATACCACGCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGCCCCTCCNTCCCTTCATGCCTTCCCTCCTCCCTCCCTTCCCC
+
GDGEAED@CEGIEHIF?DH?AAIGEIDCE?GCBCC?HCHAEAIB?CGICBG?HBIFIC9EBBA@?!EFDGFBDABIIG?ICB??A?GEG?CHFHHGADEF
@>chr21:9911176-9911317-5
CTCATACCACGCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGANCCCTTGAGTCCCCCCCTCCCTTCATGCCTTCCCTCCTCCCTCCCTTCCCC
+
EAC?FEDIFIDACEB?A?FHGFDIF@GHDF??IH@?EFGFD?HGCD?ID3HB@HGFEBHEF@=HDAEFFEB@AG??HFEC???GBGBBIBAAAC?GEDBE
@>chr21:9911176-9911317-0
GAAGGTCTTCCGCAGCAGTTCTTGAGACACTGAGAAGGTGCAGGGGGGTAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGACGGGAGGGAG
+
,EG?@?I0BH:IID@@HAEG@CCEGH=GGGDH@A@AE??IF@IGDH?4ABHHA@AAI?EDFAG@CEAEEDC@DICG@H%DGFAH?E?IE?EDFGBAGHHD
@>chr21:9911176-9911317-1
GAAGGTCCTCTGCAGCGGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCNGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGACGGGAGGGAG
+
G?GDBI?ICHE@FDHC!BABDH??DII?BF?@D@ADDCBGF@?IAIEE@@@@I?:EF?FBIEGDEHFH@AC?@GBCDIDD?EC@CIHDD?A@HGIEFEH?
@>chr21:9911176-9911317-2
GAAGGTCCTCTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGGAGGGAGAGAGGNGGGAAGGCATGACGGGAGGGAG
+
CEGGGCGFECFGDHFFIAE@FEDFIBDEAAFIBCGBFH?"C@?GC@?AFD?BDBB?@BHGDDD@I+A?IDFD3AC@A;@?AGCBCGG@DD@BDAA?FH?H
@>chr21:9911176-9911317-3
GAAGGTCCTCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCTCTCCCGTCATGCCTTCCCTCCTCCCTCCCTTCCCCTT
+
ACE@DEE?@BD@DFEDB?EFDGGIH?@BD?DDAHDIG??DDE@C?CFA@CEAHGG?@@?EA?.FFBHCIH?CBEFCF?GHAB?BF@G?HIGFE?EB@FFH
@>chr21:9911176-9911317-4
GANGGTCCTCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCTTCCCGTCATGCCTTCCCTGCTCCCTCCCTTCCCCTT
+
E?5@CDAIACDHC?IIEII@EI@CB@@CDA?@IEGDDDF@G?FA@HGBBGBDED@DCB?EGBI"IC@GGDBHIGGHIGIEHE)FGBIHI<FCFEICG???
@>chr21:9911176-9911317-5
GAAGGTCCTCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCCTCCCGTCATGCCTTCCCTCCTCCCTCCCTTCCCCTT
+
IFEIFAEA@AEEEBHCB??BIDGHECEIG@GH@H@EGCFH@HFA?@GGABFGD@AI?@CICCFIDGHEGHB?DD@DIFGBHBDB@@IFCFEIC?@IAADI
@>chr21:9911176-9911317-0
GCGGCGTACTGCAGCAGTTCTTGAGGCACTGAGAAGGTTCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGGAGG
+
EAAGH@BHIHDFFCD:DGBBDC@G?IG?HHHCEFFCB?6FIE??@H?ABEB@CCDCICC?ABEAFBA?A@I??HDEI?AGIBFIE@CBA?FBFIDG@A@D
@>chr21:9911176-9911317-1
GCGGCGTACTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGGAGG
+
@HDE@GG@ACACEHB?FHB@CDAGC@BAEGHGIDDFHE@?GBDBACEIAHGFHBF@AFG@HFGD@?AA??EIBGBAH?D?BF??FEDGDIIICBBGHHCD
@>chr21:9911176-9911317-2
GCGGCGTACTGCAGCAGTTCTTGAGTCACTNAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGGGAGG
+
GDGEFHFEH@ABIHHGCC@HFB@EE9GHDH!IIFGD1GF??EEFAABDIBAACIDABIIIDBDB?ECICGAGBABGE?HAGIGB?FD@DGD?GFIF???I
@>chr21:9911176-9911317-3
GCGGCGTACAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCCTCCCTTCATGCCTTCCCTCCTCCCTCCCTTCCCCTTC
+
D@BFAEIIC@HCFFBGIFG@CHFBDFF?DFE@?GIGF@FGBFHAC@@@HBBEFH?F@HEDEF@@D@AAG@GD??ABFBBDEAHBHI@AAIGGC?BAIGDA
@>chr21:9911176-9911317-4
GCGGCGTACAGCTGGTCTCCTGCCATACCCCCAAACTCGGGCAAGAACCCTTGAGTCCCTCCCTCCCTTCATGCCTTCCCTCCTCCCTCCCTCCCCCTTC
+
HIHDHAAB?GACAFGICE@DEIGCCAHBFGABC?IAAB"?@DIDEA@A?GECEECAI?BDEIF?AGGGE?AG@BBCDA?DBBEFII@HHFE?#GE@H@@D
@>chr21:9911176-9911317-5
GCGGCGTACCGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCTTCCCTTCATGCATTCCCTCCTCCCTCCCTTCCCCTTC
+
EID@?F?BC2FDHCDHEGEAFD)EC@B@IGG?FHB?BHIF@GADDDDAD@HH?HHGCI@I?C)CBEH?EDFDHF'BEIBAB?G?HEEEFGHEEI?DDA@G
@>chr21:9911176-9911317-0
TCAGACGGTAATGTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGGCATGAAGGGAGG
+
BFGB@IDHDEA?6HDEFB@?DCICHHCADCII@EFDC?E@?@ADCA@BI?@GBIFFAE?@?EBHFD@EI@EDA@CAIGDFHHF@CEGAIDC@@GDIC?EA
@>chr21:9911176-9911317-1
TCAGGCGGTAATCTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGAAGGGGAAGGGAGGGAGGAGGGAAGCCATGAAGGGAGG
+
FF@@/ABEGIBC??FHAHIHAHIHD@I@ACDI?C@HCAADBAGDE?CIIGDHCADHAAFBDIAHCHF?BIFH@@BFADBFEHHHB@I9?DHE@CGF@IAI
@>chr21:9911176-9911317-2
TCAGACGGTAATCTGCAGCAGTTCTTGAGGCACTGAGAAGGTGCAGGGGGATAGGCCTGCAGNAGGGGAANGGAGGGAGGAGGGAAGGCATGAAGGGAGG
+
D?@GB?A?CBHI@FI@HHIIGFDAEFGB<@?IEACDIBGGDBED?GIGH@I@BGEDCF@??B5FEC@BIB2@DGEBHI?@AH@F@EBFEDHIHFIIFII?
@>chr21:9911176-9911317-3
TCAGACGGTAATCAGCTGGTCTCCTGCCATACGCCCAAACGCAGGCAAGAACGCTTGAGTCCCTCCCTCCCTNCATGCCTTCCCTCCTCCCTCCCTTCCC
+
ECHEDGBFGBIIHGDEAF@G?@B?@GBIGBIH8I?IFF?C=EE?@BD?A?G?4F@E0GDIEF??HAGEIE?@7CEFCIIB@H@DAGH?HG@BAHCCG@DC
@>chr21:9911176-9911317-4
TCAGACGGTAATCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCCTCCCTTCATGCCTTCCCTCCTCCCTCCCTTCCC
+
DCDI@CGCCB@??HIHBDABFBBF@?GAIBIGHFECHDHGE?EAEGIGHGFGCA?GDI@EFIG?BFAI??D@GHIIGIEBCGAICHBFGFAFECCCHFGD
@>chr21:9911176-9911317-5
TCAGACGGTAATCAGCTGGTCTCCTGCCATACCCCCAAACTCAGGCAAGAACCCTTGAGTCCCTCCCTCCCTTCNTGCCTTCCCTCCTCCCTCCCTTCCC
+
EIE,D?FI?BAEIFECFEBGCA?HCEECA?GFFFA?IDEHHECCGIGDGGDI?DIGDDCHI??IEEHFC@AGCB>FHF??FGFGHDGFFCH@?GFHE??H
@>chr21:9911731-9911843-0
ACCACTATGTCTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAGGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATAGAGGG
+
G@AAHGB@GCIH@DFHBBECI??EBCFBAHAEA?AFBFDGB@BCF?E?F?H??@HDDD?IHHHGEGHI@DHD@FEIDBCGBCIFCI?F@H@GC@?BAGEF
@>chr21:9911731-9911843-1
ACCACTATGTCTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAAGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATAGAGGG
+
IHFBBH@GDCCE@CGDDEBED?AEIHC?EA@GFA@DDFHGC?ADDABID@AIIIEC?GAGFHCA@GEFBDHGIBF?@BCDCFGBEBCEDGE??DGAADAF
@>chr21:9911731-9911843-2
GCCACTATGTCTACTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAAGGGGCCAGATTTCCGGACTCAGGGGTCTCACGCATAGAGGG
+
*FFBBEDCF?H@'BFAIEHD?DIEAIAIAE@/@EG?H@BG@AFAHGIIEEH?AFCHIDAHFFF?FCGBCGBH=?EDBCABG@GBHFIAG@BBGDCHHI?D
@>chr21:9911731-9911843-3
ACCACTATGTCTGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCTTAGTGACAGGAGGCAGTTTTGCCCCA
+
D@EDE@DFIABHBGG?CA?A?ACE@?F@DIEHC@FD?E??GI@F!ADCFH?EEBHGGHGCBGHI@H?GB??GHI@C@BCEEGF@AABA@FAHEGBDCGBC
@>chr21:9911731-9911843-4
ACCACTATGTCTGCAAGCACACGGGAGACCGGCCCTCTATGAGTGAGACCCCCGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCCCA
+
EGECAHEB?ABFIDAAECDFDB@ABEG?@D/@DDIFFCFIB3??EII?@GEB7AHGGBFF?GFB@G?EDBGHG?BE?IBCIDEI?DH@IGC@G?C@FDF?
@>chr21:9911731-9911843-5
ACCACTATGTCTGCAAGCACACGCGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGTCCCA
+
IGFGCEAHB@B?DHC@HD@DA@H"GDEFIA@@FDDDI@?BBG?CHIHCAAIA?@HBE@AICHAFDCCCC??CEH@G@B@F?HDDE?I@GHADEEI>I@EH
@>chr21:9911731-9911843-0
CTCATACCACGCTGCTTGGAAGTCTGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAGGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCGTAGAGG
+
HC@GFFBE?G@@IG??IEFI@DHB,AICHGBDAE@?FII@ICDFGFCFBE9GBEDFDBDHEFIAEGDHECE?D?EIEC1BFC?IB@HHEIGDH:BHI@??
@>chr21:9911731-9911843-1
CTCATACCACGCTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAGGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATAGAGG
+
IE?HD@?CGEDFB?EFID?EDI?CACEABBHHDFEHIHDAHGIGGCFFGBGBCE@HDAEBFBACA@AGDGIE@@A@@@HHI?AA??GICDDFECGFGABB
@>chr21:9911731-9911843-2
CTCATACCACGCTGCTTGGAAGTGGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAGGGGGCCAGATTTCGGGACTCAGGGGACTCACGCATAGAGG
+
IBI@?HB@CAFEEBAEFICCBIF(D@DIAGABFCEF@G@GAE?@DEBHH@AEAD?@ACDDE@HBEDHFIIH@FCAG@F?BEBI9A0GBBHGICG?HDFAD
@>chr21:9911731-9911843-3
CTCATACCACGCNGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCATGAGTCCCGAAATCTGGCCCCCAAGTGACNGGAGGCAGTTTTGCCCC
+
DGEACIECICHF0BBH@ABGCHF?DDCAC?GHDFBCGAG??F@CH@ACECBI,CA@DGFF@FEEDEHIACFAEIH;@@EACB#IEGDG@DAID@AC?D@?
@>chr21:9911731-9911843-4
CTCATACCAGGCTGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCCG
+
IHFI?FBBE5ECC@BCEIBF?@E@?FIEAH?EDIB?BA@ADA@AB@DAIEFECAFIAAEHAIFIDFB?G?BFFIFDHGF?IG?GED?AD?@DHD??DBH:
@>chr21:9911731-9911843-5
CTCATACCACGCTGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCCC
+
D@@CDC?DEAHIEC?DCC?EGEHHDGACCG?@HIIHI@BIFHCFEGIHH@F@FFG?EGH@@IHAC?GA?@?@GIAFICDAC?H@ADFG@IEHIHD??CCE
@>chr21:9911731-9911843-0
GAAGGTCCTCTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAGGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATAAAGGGC
+
IFHHFDFGHBIBCI?I?IGECAHEBGFIEE@FBDCI?DFCDABGIHDHAC*DCBCIDBF?EEDIDFDECHG?BD@DFGAGFE@HDE?HHFEHDE3HHG@@
@>chr21:9911731-9911843-1
GAAGGTCCTCTGCTTGGANGTCGGGGCCTTCTGNGGCAAAACTGCCTCCTGTCACTAAGGGGCCAGATTTCGGGACTCAGGCGTCTCACGCATAGAGGGC
+
IC@DICDC?IGCHECAFF/IG@IDDCBGCC<AE-GFBICBDAAFAFHBEI?I@AFBDEEI@CGBHIDCFIIGFCIBIGDHI=IGEBE?H@FEHG?EDCBI
@>chr21:9911731-9911843-2
GAAGGTCCTCTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAAGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATAGAGGGC
+
IADDF@?ABHFGBABGBG?GEFCGBCIAHF?BFE@?DFIDAHIEGDEIDEDIEDFBIBDDFCDABGHAACEHBE?DAFFGDDHCIEGB@@B?I?B?EDBG
@>chr21:9911731-9911843-3
NAAGGTCCTCTGCAAGCACACGGGAGAGCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCTTAGTGACAGGAGGCAGTTTTGCCCCAG
+
<@GBDBI?HG@E@II?EFBEA?CFC@D&D@C@DD?IBIB?IIGD?@?HDB@?FDDHFB?@ECG?FEHDI?CAA@GGCBBI@@ABFABIHE@CIAF@DGGI
@>chr21:9911731-9911843-4
GAAGGTCCTCTGCAAGCANACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCTCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCCCAG
+
HE??IC@FF@DFEA?BAG.IAH@DCI?ICDGHGFDDC@HC@CBGA@EBGDD?EICEI7?CDDIHDAIGGFIH@HC??HGEFEC@HEACFADH@FE@HDAB
@>chr21:9911731-9911843-5
GAAGGTCCTCTGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCTGTTTTGCCCCAG
+
H@F?DAGI?ECBDA?G?E@GABGEEDH@HH@IAIBBH@GDFHEGAAF@IBAH@EDHEIGEHB@AEI?B@@DG?CHF@@GCBCBFBBA3GBGEAEAGBH?E
@>chr21:9911731-9911843-0
GCGGCGTACTGCTTGGAAGTCGGGGCCTTCTGGGGCAAACCTACCTCCTGTCACTAGGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATCGAGGGCT
+
GCDBBCHGAA?B?G?FGEEFI@GDIGCFF?FCFCFI?BF+EB8??CBECIBBA1@GDDDCH@HED?GDFHCEADEI?GFAAF@IGDGBIB?F7CGGFCDB
@>chr21:9911731-9911843-1
GCGGCGTACAGCTTGGAAGTCGGGGCCTTGTGGGGCAAAACTGCCTCCTGTCACTAAGGGGNCAGATTTCGGGACTCAGGGGTCTCACGCATAGAGGGCT
+
GBIEF?D?H$DF@AE?ADEEADHFEC?CG6EFBACI?EDIACC@CGHBHBBDGBGCD@FBF5FIEI??ACBDC@I@@CGHCIDCAHFAHABA?@GHHBAE
@>chr21:9911731-9911843-2
GCGGCGTACTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAAGGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATAGAGGGCT
+
@?BIBE@BFGGICECBC@IHGIDEHEED@EFDI?AIHA@BCEEBH?I?@EAIHCIIAFDHHGEGF?@E?DGCCCFGGAE@@FBIFDFAGCBGHABFEDFI
@>chr21:9911731-9911843-3
ACGGCGTACTGCAAGCACACGGGAGACCAGCCCTCTATGCGTGCGACCCCTGAGTCCCGAAATCTGGCCCCTTAGTGACAGGAGNCAGTTTTGCCCCAGA
+
.BCI?IC?BH@@E?D?@EEHIGICDDB?C?@FDE@DBAAHA@F6?CCEB@DA@AEBG?CFDFHCCHB@@AB@DBDIBADEEBI@$FAAEIF@@GCGIG@G
@>chr21:9911731-9911843-4
GCGGCGTACTGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCAAGTGACAGGAGTCAGTTTTGCCCCAGA
+
?C?BA@?@AGADHE?EIADGIB??HDIGCFAD?GH@HHI@@F@EFCAB@@IABHCG@CHHDGGHAHIFEFFA$HBF?BIDBDG?#?CIHB?DF@GCEEGG
@>chr21:9911731-9911843-5
GCGGCCTACTGCAAGCACACGGGAGACCAGCCCTCTCTGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCCCAGA
+
AF?DG!EAAECICEFCF@BIEFH@IEED?BIDCBGB)CIIFIH?FIEFBBC#FFDEAHIA@HHAA?IDF@CEAHEEG?IIHDD@CFIE@DBHIEBBHGEI
@>chr21:9911731-9911843-0
TCAGACGGTAATCTGCTTGGAAGTCGGGGCCTTCTGGGGCAACACTGCCTCCTGTCACTAGNGGGCCAGATTTCGGGACTCAGGGGTCTCACGCATAGAG
+
FFHFACCCHCBF?ABABGIB@?FA@HFGCIIIIDHCFAAHHI7AHAI@@@HE@AHEEEAEF,DDIBAEECDHGIEDIGAH@C@@EIBG?IDH@F?GIIB@
@>chr21:9911731-9911843-1
TCAGACGGTAATCTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAGGNGGCCAGATTTCGGGNCTCAGGGGTCTCACGCATAGAG
+
IB@E@E@B?B@I@??I@E?FFB@FD?GFIA@DB?B@?EBCA?EDE?C@ACG?DEEIDIBDAF6IC?AIFEF@HACDF-CDBBDHABAEAHABF+?FGCGH
@>chr21:9911731-9911843-2
TCAGACGGTAATCTGCTTGGAAGTCGGGGCCTTCTGGGGCAAAACTGCCTCCTGTCACTAGGGGGCCAGATTTCGGGACTCAGGGGTCTCACCCATAGAG
+
@G@F?FGCCCDEAFB@C@BFEE?CAGFFCAC@DIBFACA@HEA@@EDAH@H?EIC@FA@CD??@HGCD@HIC@@ID?HIIGD?CDAGIBEAC3BGIBAHB
@>chr21:9911731-9911843-3
TCAGACGGTAATCNGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGNGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCC
+
?GAF@D@AIADFC0IE?EDDFAEFFICHEBEDC?BABGH?CBBG?IFICHD@A@ID8@FEEHHEEFFFCB?A@@EGIH?AGD?DHGGA?GHE@CCIBCI?
@>chr21:9911731-9911843-4
TCAAACGGTAATCTGCAAGCACACGGGAGACCAGCCCTCTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCC
+
FDC!B?IGAIE@GDHCIFIGDEBDIFFFBIFBBFGABC@AADCBH?HCF?DFD@EDCEGABDDAAI@HEIEGEG@I?DE?@FA?BBGD@IEICDIIAHAA
@>chr21:9911731-9911843-5
TCAGACGGTAATCTGCAAGCACACGGGAGACCAGCCCTTTATGCGTGAGACCCCTGAGTCCCGAAATCTGGCCCCCTAGTGACAGGAGGCAGTTTTGCCC
+
@EDHHCDBHIIACICBGII???CHCHHIICDI??ABED6CFCFFEH@GBECCABGI?ABHIGF@HDIEIH?HBBCBE@CCCFABGAHDHEE@H?FEDA?D
@>chr21:9911840-9911920-0
ACCACTATGTCAGGAGCCACGTGGCTTGTGCACATCAACTGACGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGCTCGGAAG
+
EACEHEI?EEI?B?EFIIF@?B?HFA?H@-FH@CI4BEDEG4GGHAGHIFHIACBBFFCHC?E?@@ACAG@@CD?AC?IHAHF?AID?BAA@,AEBCID?
@>chr21:9911840-9911920-1
ACCACTATGTCAGGACGCACGTGGCTTGTCCACATGAACTGCCGGNGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGAAG
+
DGGAAGFDFFDDIAH:*CBH?DIGGIH@EG?A?AHEAGBFGHEGE*GFIBCBAIHGGA?ADGCEEBHAGH?GGBEG@@HGCGEFHEB@BG?@?DAHIG@F
@>chr21:9911840-9911920-2
ACCACTGTGTCAGGAGCCACGTGGCTCCTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCAGAAGTCCTGGCCACCCAAGGCTGAGATCTGAAG
+
ECCGHG%?EGH(CA@EEFAGGDHCGI6<AG@GGEDDI@?@CIGIDHIEIGH@@DDAB?HDDDE?@DI=BBII?DCCHCFDIICC?@I@CIADDHD3C@HD
@>chr21:9911840-9911920-3
ACCACAATTTCAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTCCTGAGATCGGAAG
+
HBHFG"GA8ABAEFEHAB?AFB@BIFC?D@AIAFEDCBF?B@@E?GFDCFDID?IG@AI@BF?H@@'AFACFFBEFAI@ABB@GDGICGDFDEHCDED?F
@>chr21:9911840-9911920-4
ACCACTATGTCAGCCTNGGGTGACCAGGACTTGAGGGTACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTCCTGAGATCGGAAG
+
??E??E?DGH?HIDDG"AGIFG-AFFI@BAFHH2EDE1D@DHI?EC?DDHBH?B@DIH@EGHGF?DDIFH?3HGDAADCCHBFBF@BH?AGAEAABFGG@
@>chr21:9911840-9911920-5
ACCACTATGTCAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCGGTTCATGTGGACAAGCCACGTGGCTCCTGAGATCGGAAG
+
DCFB?EBHEHAHDC@BBHHCBIIHDCICGDCE?@FBICBDID?FB@IDFAH@FDG?DC@B=DECADC?F4FF@?HC@?G?IBCCHFBHI?HGG@?HHCI?
@>chr21:9911840-9911920-0
CTCATACCACGCAGGAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGAA
+
FFBDAHBG@HFGHHFC?A@FBCF?HCBG@AGB@CIGGBHFDEFGGIGDGAAGH?HD@@@H@ADHF@HG?CDIEGHFFH?CHBGEADHFGI!AADHAI@ID
@>chr21:9911840-9911920-1
CTCATACCACGCAGCAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGAA
+
BGIBFICHGFBAEAIAGCIECCGC?@?G?CAHHIFC?GEEBBIBFB?GFDA?DGCF@DC??C@GCAH@IDACFFCIE@@ADHAIIIE@BEHE@IE@FCH@
@>chr21:9911840-9911920-2
CTCATACCACGCAGCAGCCACGTGGCTTGTCCACATGAACTGCCNGGGGCTCCTCCTCTCTGTGCCGACAAGTCCTGGCCACCCAAGGCTGAGATCGGAA
+
C@BH?@D?DCIDGHCB?CIEGCGG?IHEBFCA@B??FAHBIFG@*@IGHCI@DA?DFECCFDF?@F#?I?AGCBGG?CBD@DBGCFHG??@?EAB?DD?@
@>chr21:9911840-9911920-3
CTCATACCACGCAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTGCTGAGATCGGAA
+
C@E@IEC@?DFD??IAHCIEHED@?CCEEDCF?CAED@B,H?A?IEF?IDGH$EEFDBAGBECEDBHI?FEIIFBGAII@BI?H@HFHCADBAIIGI@?G
@>chr21:9911840-9911920-4
CTCATACCACGCAGCNTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTCCTGAGATCGGAA
+
IGD?IE?@?FBADED1FHBCEGABBFDCGHE@@BFIBHDD@C?HDCFDI@@?IAHCIFHFF@GHIGCECGDAACG@DCGEHFGEGGA@@HFCEHBGGCB?
@>chr21:9911840-9911920-5
CTCATACCACGCAGCCTTGGGTGGGCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATNTGGACAAGCCACGTGGCTCCTGAGATCGGAA
+
CGIC?AIIHAEAHIAICIFE=DIB%DE?GEDDAFE?DA@?HACGE@GGG?C?AGAFADADCBIGACCF9I@E@@CIC@GH@FIC@IDAH@EFG?EDIB?F
@>chr21:9911840-9911920-0
GAAGGTCCTCAGGAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGAAGA
+
C?CCHI0IFCHGGEEGIEGIEFAHFHF@ICFFGFBIDA?I?AFGACBEECAGBBCFI@ECFDHEGBCDHEG@DFF:AGF@@GDAB@41HFIH@2CADEIC
@>chr21:9911840-9911920-1
GAAGGTCCTCAGCAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTNAGATCGGAAGA
+
CFIE?CE@?EAD@ECCIFB@CCD?AGHDCGDIDGCDA?@EFBBAHEEIIDBA@HAD@B@D?FCIDCHDHDIEFAH?BIBBEEIFECBC'AEIDEDHB?FG
@>chr21:9911840-9911920-2
GAAGGTCCTCAGCAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGAAGA
+
?HBIHC?BGAGB??GFGAH??CAE@CG@?@D@H@DHE?IGFI?C@?@DEH@EHHECBFCBIB@B?DFHH@G?FDFEGEDFG@I?CC?C?EEBDBECG?CC
@>chr21:9911840-9911920-3
GAAGGTCCTCAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTGCTGAGATCGGAAGA
+
H@C@AGF??HGCABIIIADFG@EHAAG@B?BBIHAEE@@ID@C?FIF?@D??BB@CAGB??EBD@ICGCBBGEFHCC?B@IBBAHA@I?I?HD@DHF?GF
@>chr21:9911840-9911920-4
GAAGGTCCTCAGCCTNGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTCCTGAGATCGGAAGA
+
EBAECD@BED@C@CE!EGDGDIEFIDDGA@AICFGA@CA@IC@GE@FCA?GICIDECBABDIFI?AFHECD@AE??IF@EDADE?CDGDAHHICHC@FAB
@>chr21:9911840-9911920-5
GAAGGTCCTCAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCACGTGGACAAGCCACGTGGCTCCTGAGATCGGAAGA
+
HCEBAHICBCHFGBAGEDIGFAFEIAEAF@IGHB@?D??FIFEF?EHEBB@IFID(CGAEEF@FC2EE?GE@@?AEIFI?CHDIBIE??C?@EABC?FI?
@>chr21:9911840-9911920-0
CCGGNGTACAGCAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGATATCGGAAGAG
+
&CEA,?G@@BHIIGIHAD@BG@CIFCH@IAHAG@BCB@@AC?BIACICHBGCCCIEFI@@CHAABDICB@IG?IADCD@CAEDEGB?CH5FIBCHCE?B@
@>chr21:9911840-9911920-1
GCGGCGTACAGCAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGAAGAG
+
?EAAHDIGD?IC?ADIC?BCFH?GFFIBIEGI@DEH?DB?HHIGGD?I@BGF@GBBE@BFAEDAFI?BAFEGG@?E?ICD?EFGFAFBIBEDHGGDAIBD
@>chr21:9911840-9911920-2
GCGGCGTACANCAGCCAAGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCNCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGAAGAG
+
EGIIAD?@ED+D@?AIF3HAICIGGEE?CBDBFG?EGGE@EEGGBCCGIAEGIAF6DBCEC@GB@IDEG?IHFIFC@@DFHBIH@EA?BG??CBFFEBBH
@>chr21:9911840-9911920-3
GCGGCGTACAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTGCTGAGAACGGAAGAG
+
G?A?@GAGFB@FDI?DBAFGCCCGDICCHIIHD@C?BF@CAEIDBDAHFF??BD7CEEHACDFHGH@F@BH@EIGAFCC@EG?HBBIIH@?'EC?IFBIF
@>chr21:9911840-9911920-4
GCGGCGTACAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTTGCTCCTGAGATCGGAAGAG
+
BGEBBICB@@GGB?@IBIA@DHGCICEGE@ACHBGH?@HIIDDAFAHIBG?BCGDBCBAHFEGGFB@EDDBHHCIDIHCB(BI$=H@DIFD?BEEBIAA?
@>chr21:9911840-9911920-5
GCGGCGTACAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTGCTGAAATCGNAAGAG
+
FIAIIIG?FEA@CBAFFBF?HIGCEEEF??AFBA?AADDIIH@EG@CD@F@HH@BDGEG@E@A@FFECD?GIAA??EGCHDBDAC@A@D!ECDC(HIEAE
@>chr21:9911840-9911920-0
TCAGACGGTAATCAGGAGCCACGTGGCTTGTCCACTTGANCTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGA
+
ACAC??AIFABF?HBIF?DIAHCDIHFFID2CBE?1BDG+AIF?B?E@BED@IEBIICBAFCHFCFCFHHGFCFCGHDE@EADA@FECGEFFGHDGADDA
@>chr21:9911840-9911920-1
TCAGACGGTAATCNGGAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGATCGGA
+
DAAIFC?BCF@CI#H@HIFF@G@DE@?BG?CFGHICIE??HDF?I?AF@ADBBAH?GG@?4F@HFA?HBCED?GEHCIHE?B@GEBFDI@?AFIHAIGGC
@>chr21:9911840-9911920-2
TCAGACGGTAATCAGGAGCCACGTGGCTTGTCCACATGAACTGCCGGGGGCTCCTCCTCTCTGTGCCCACAAGTCCTGGCCACCCAAGGCTGAGCTCCGA
+
FD?@DDHA?B?AC?FIC?HACG@IACGEFBE@AFEDB@AECII?HGGEHH@EGE?DDGB?DHACC?BIEHICI@?CA@IE@IFEHAEBHA?@GI-?@>DD
@>chr21:9911840-9911920-3
ACAGATGGTAATCAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTCATGAGATCGGA
+
#IIGB6C?IABECIE@I@@?@?GB@ED@FBI?GCIGFIDGBA@GCEFA@ADAIABEICDEG?GHDABG@EEABH?A@DGIBBBDAFGAD2CGDB@E@CIA
@>chr21:9911840-9911920-4
TCAGANGGTAATCAGCCTTGGGTGGCCAGGAGTTGTGGGCACAGAGAGGAGGAGCCCCCGGCAGTTCATGTGGACAAGCCACGTGGCTCCTGAGATCGGA
+
IGEAC"I?ED?BHDFDFCB@DGE@EEF@A@@6D?BFBI?C@I?DHFBHCCHBHG@FIE?AHDBCADACAIEFGIE?BA?BF@GE?@I@?GIEGFCFI@GA
@>chr21:9911840-9911920-5
TCAGACAGTAATCAGCCTTGGGTGGCCAGGACTTGTGGGCACAGAGAGGAGGAGCCCCCTGCAGTTCATGTGGACAAGCCACGTGGCTCCTGAGATCGGA
+
CHBIFF3AECBA?BCBCCA?CFGFAECICBCADCBII@FFHI?I@BEHHADBE@BHB?H"GGFAIHIBABHGCC?EBBGBEDGDBEDDHGBAHBEGGHAC
@>chr21:9911933-9911988-0
ACCACTATGTCAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCTTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
BDGBCEI?D@C?@A?AH@EDFIHID?GBFFECFI@@@@FBIGC@GHFEGHAAHF@BE???GEICGDCC@?H/IAAEBCB@GDD@HA@IHHCF??D??IBE
@>chr21:9911933-9911988-1
ACCACTATGTCAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCTTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAATA
+
E@?GCGGBBAGHHFHHEGBHAFBBCFBDFDF@FFEF@EDIE?CGGFBCHH?HA@FEFEH@H@?E?IHDA@@I?GDGFBBHIG@CBCDEFHHCCFHH?B(F
@>chr21:9911933-9911988-2
ACCACTATGTCAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCTTGCTGGTGGCACTGGCTGAGATCGGAAGAGCCAAAAAAAAAAAAAAAAAAAAA
+
CI?A?A@@GH@EHBF?BBGAFG@D@CGABAEDEDE?FGC?ECF@?DECAHIDA@C@FHFDFDCIHC?FIHEHF?HCHF;?CDI@FBGBB?@HDCEBIGDB
@>chr21:9911933-9911988-3
ACCACTATGTCAGCCAGTGGCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
F?IBD@EE@BABHBAA@IC4DGGBABGGE?EGIGHI@CH@DCD@HGIEB@IEH@FC?@C?EHEAAAGIIGIACDCFDEA?E@HBFGH@BCFCEA@D@DEI
@>chr21:9911933-9911988-4
ACCACTATGTCAGCCAGTGCCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAGAAAAAAAAAAA
+
ABBGFF@DFDDHCFFBCDBI@C?BDDBEEGGBBCIEABHEEE?C?IFA?H?BCBAGG@EEDCCIACEHBAGBCBFBC?FAFCBBFDBI:BDIHDC@FFHA
@>chr21:9911933-9911988-5
ACCACTATGTCAGCCAGTGCCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGTAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAA
+
?DBI@A,C@E?GHI?FIHBCHGABGEDBEF?GBACH?GBA??IAECHB@DCDAIHEDIB6DHFI?CCF?D@BBEGBDGGEIAG@DA?AFGFEH?BCAGDB
@>chr21:9911933-9911988-0
CTCATACCACGCAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCGTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
FBG@IEFIEEEHEDA?GFFFAHBF@ADCA@F??ACBICDA@??AE?EGGDFDFIE@ABD@HBB@GI@EEBAE?CB@H@AGEFGIIA@DBABI@HAHCI?D
@>chr21:9911933-9911988-1
CTCATACCACGCAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCGTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
FBCEGCE?GIGG@BBDICHHBA?IFBADEDD?@GIAHBIBGEA@DCH?EFBAFHBG@GFHDGFDEFDFDICGE@?BAHHG@@FB?CF@ICGB@FFHDIA?
@>chr21:9911933-9911988-2
CTCATACCACGCAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCGTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
EEIA?DDIID?A@IAGIB@FEEHICACICCIHGEF?FIFAEF?IEE?IDAFB@ABIGABBGEGIHED@FGCDIB?CI??@ECBD?GIIC@?@A?I?GFA?
@>chr21:9911933-9911988-3
CTCATACCACGCAGCCAGTGCCACCAGCACGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGAGAAAAAAAAAAAAAAAAAAAA
+
BICABCCII@G@?BHBCFCE?EHHIAEHGDEA@@?GGADHGHAEIGEFEED@@HA@?D??FH?BBGIC@GFIID?AG@$@DE#CEAHHB?CBG@??EDA@
@>chr21:9911933-9911988-4
CTCATACCACGCAGCCAGTGCCACCAGCACGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
AIGHFABGIFDGCHCCCHGIFFIEHH@HBCH@FBACFBDF@@B?AFAIIDIEGGI@E?E@AGBEDHHBD?ABI@DB@I?@@CDFGGIAGA@CE@?BEBCE
@>chr21:9911933-9911988-5
CTCATACCACGCCGCNANNGCTACCAGCTCGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAA
+
@?ADGEAHEBC?!CC>B';FB/EA?HHI1BHB@DAFGCDGIII@AFHEBDEEFB?BGBGEAIDH?DHHFFEHHC@DBB@E@GHEAHIH?BHGIEC?C?EA
@>chr21:9911933-9911988-0
GAAGGTCCTCAGCTCCGTCTTCACATGGACACGCACAAGGTTGGCTTGCTGGTGGCACGGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAGAAAAA
+
?IC?C?DFGCCDCCHCIFGA8AA@DAFC5?@HEGAED@@FHC@?AE?AADBIBGABHE!ABCDEAHHAFFAAEDCGCGEE@C@EFEAADA?G@?9BAAI@
@>chr21:9911933-9911988-1
GAAGGTCCTCAGCTCCGTCTCCACATGGTCACGCANAAGGTTGGCTTGCTGGTGGCACTGGCTGAGATCGGAAGAGCNAAAAAAAAAAANAAAAAAAAAA
+
@DA@HCAB?HBHI@CBI?EC@HCCADCD?HBHCGE1FAGD?CE?@G@@?EG?BHIC?HFCI?IDBIBDIDG@H?IC@=BGCDDHA?D@G2?AFC@FG?DB
@>chr21:9911933-9911988-2
GAAGGTCCTCAGCTCCGTCACCACATGGTCACGCACAAGGTTGGCTTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
@EI@BBCHFCH@AGIDCGH#GFDBECGE@BDFBC@CE?IABGEACDCHB@E?G?G%GAFIHG@DCIGF@CAIEEFIIDGIGFBDEBCCBH@ABB@GE@FD
@>chr21:9911933-9911988-3
GAAGGTCCTCAGCCAGTGCCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGATAAAAAAAAAAAAAAANAAAA
+
DFABEFEHIDDIFACADIGE?GFIDB?CF@HB?EFCEB@BEFHG@BGF??DA@GHEEECDCGGHI??HDBDIDHHDGDE1ABEF@ICCBB?EIAC(@GE?
@>chr21:9911933-9911988-4
GAAGGTCCTCAGCCAGTGCCACCCGCAAGCCAACCTTGTGCATGGCCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
A@CGEB@IIDHACIIAFCED@FH9ECCAHFGED??AHFGFB;GB-GGEHFHHFCDEADHDFEHECFD?DFB@@DF?IGCGBACFGEHBEICE?I@F@BH@
@>chr21:9911933-9911988-5
GAAGGTCCTCAGCCAGTGCCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAA
+
CID?DDE@DCD@DBHG?@CDCGGAH?IC?C;@GDG?@HEADEFF?IIH?A@@HBCEDIF@@?G?@I@BGFGGB@ACEGG?ED?GDBCCID??E@BEG@DB
@>chr21:9911933-9911988-0
GCGGCGTACAGCTCCGTCTCCACATGGTAACGCACAAGGTTGGCGTGNTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
BG@IGAHG@?@HECCIIBG?E??GHFDH>@AI9I@I?@FHIH?BGG@"CH?@HEBBI@GBBCAEHFBFAAGEBICC?DBIHADIHCB@HHADBG@FECEE
@>chr21:9911933-9911988-1
GCGGCGTACAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCGTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
BD??@BEG?IEABDAI@DBEAHHBGBGAHBHIEDGBDBBDIHCAE@DFCFGEGIEEEFHE?IABAEBFDB@A@GDAECGB?@IIHDCEEFGBIFF@DDED
@>chr21:9911933-9911988-2
ACGGCGTACAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCGTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAGAAAAAAAAAAAAAAAAAAAAA
+
)G@B?EIA@?EAAGBIEF?IGBDFIFA@EBBG?ADIIA@G?HEED?EHDDGGCFAGDID@IIC@EGDHAC@@BFFAFG7FDA?BBCHGAE?IEB@HF?IH
@>chr21:9911933-9911988-3
GCGGCGTACAGCCAGTGCCACCAGCACGCCAACCTGGTGCGTGANCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
G@FE?FGDAGEFH?AH?EEFCIAACBIFC@DFC@B6DHI?IGHD8E@DDFF@BB?FHHIIHAAEADFGACBIFF?EBGIAHGI?AGAH@IICBE@BBG@H
@>chr21:9911933-9911988-4
GCGGCGTACAGCCAGGGCCACCAGCACGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCCGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAA
+
A@BFH@ECBIC?IIF,?@FC@EBDIEFGGFF?FDBFF@AIBE+IEBIDBBICC@CHFBCDHBFAGEBC0HIIEHBIH?FEEBEAECI?CIA@EHDGGF?D
@>chr21:9911933-9911988-5
GCGGCGTACAGCCAGTCCCACCAGCACGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAAAAAN
+
DBFB?FC?C@I?AF<C(D@HDHCEI?FHFIEF?C?ACHHIFGA@BEBCECCFIHHB?GCDEHA@?@AIIIIEGI??F??A@BFHDI?BBFH?AFDEH?E0
@>chr21:9911933-9911988-0
TCAGACGGTAATNAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCTTGCTGGAGGCACTGGCTGAGATCGGAAGAGGGAAAAAAAAAAAAAAAAAAA
+
?CGIEACHI@?@-DC@DFEE@BCIEFC?EGCGHC@@ICIEDAG@?EG?FCGI@I?+EFCEA?IG?GIFAAGHGEGC?F?0DFEGBDEAACGIAIBCDAEF
@>chr21:9911933-9911988-1
TCAGACGGTAAACAGCTCCGTCTCAACATGGACACGCACAAGGTTGGCTTGCTGGTGGCACTGGCTGAGATCGGACGAGCGAAAAAAAAAAAAAAAAAAA
+
I@GEEFEGE?H<A?DGHACDFECB.A?I4I?2B?BAC@@?BIFIDAHIBHAGHEGEGGADEBIBHBB?B@CHH0B:@BCFFGECIBGBGBEEAHAAEH?D
@>chr21:9911933-9911988-2
TCAGACGGTAATCAGCTCCGTCTCCACATGGTCACGCACAAGGTTGGCTTGCTGGTGGCACTGGCTGAGATCGGAAGAGCGAAAAAAAAACAAAAAAAAA
+
EI?EB?FHCBDCG?G@ABB?GBAFC?IC@HHCB?FFEC@?GCAHC@HAC?EFCG??IGECAGBCB?I?@IDGAEDIA?AACG@?@GBFHC3D@EG@DFFH
@>chr21:9911933-9911988-3
TCAGACGGTAATCAGCCAGTGCCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
CID@CGCDHG@@@EBIBAE@GEC?HFCAEDICDBIAGGAGG?IF@?HD?E?EGIBBEA@IH@GCE@?@FC?CACBBHDCC@E?DBC@FBDIFCH@E@BF@
@>chr21:9911933-9911988-4
TCAGACGGTAATCAGCCAGTGCCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAAATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
FBDCEGAF@E@BCHIHCDEIBDBBECICBBBHCFCG?F?GFAIHAE?DHBC@DEAIBCBFDGCABEIF'AC@CEDFGC?FIAIGHECDAAECH?DFHB@G
@>chr21:9911933-9911988-5
TCAGACGGTAATCAGCCATTGCCACCAGCAAGCCAACCTTGTGCGTGACCATGTGGAGACGGAGCTGAGATCGGAAGAGCGAAAAAAAAAAAAAAAAAAA
+
I@B@EAG?B?CEIFDCBB(ABF?HA@HHCH@CI?BBCAAGIDE?DEEDCA?I@BIICAC@@FAFD?EDCCEIBEDEIGB@@CHIAHCHIDFBCGFD@IIG
@>chr21:9911985-9912071-0
ACCACTATGTCTGTACTGCATGTTGTCAGTGGTAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGAT
+
BEFHICHDHFGBA>ADBH@FCFEI?ABCIBFCC@EECB@IBFIBHCIDAHBCACAIFBBCCGAAGB@IIIBBDCG?FEGFDFEIGIIF?FBDIBAB@F??
@>chr21:9911985-9912071-1
ACCACTATGTCTGCACTGCATGTTGTCAGTGGTAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGAT
+
AAEICHGHBGH?FHBFBHIHHCE?GEFCAHBG?G@E?@HH?FIIHFA??HCF@GDBHCHFB@EBGBED@@DBIFBIACBCCHDE@@?@A@BG?FBGBAH?
@>chr21:9911985-9912071-2
ACCACTATGTCTGCACTGCATGTTGTCGGTGGTAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGAT
+
HGACFA?@HGEIICBG??I@DDEGG?G4@HFFA@GHDAGH?@EHFAGBC@EE?AFBA?ED?@C?IGFE?B@AEBIDGFFDG?F@G?EEFGGEC@CC@HCD
@>chr21:9911985-9912071-3
ACCACTATGTCTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTCCTCCATTACCACTGACAACATGCAGTACAGAGAT
+
FDDIDBHCCDF?EH?F@HFEA?F?DBHACFEFAB?DA?B?IDGGFCIDIIA@@H@C?BHDIBFGI:FDIGAAHBH@DHB@A@??HBE?AFAD7?E?ABCF
@>chr21:9911985-9912071-4
ACCACTATGTCTGCTGGCCCACAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCTTTACCACTGAAAACATGCAGTGCAGAGAT
+
?AAEGGBEBFA@GB?I@D?@I.GBC@HDF@HG@EI@FDED@@?ACADCE?I@@F?DDIAIB?AGACAEFE6CFGFAGCDBD)AB@DA@DIH?E@CH?GIA
@>chr21:9911985-9912071-5
ACCACTATGTCTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCATTACCACTGACAACATGCAGTGCAGAGAT
+
CHICF@@FG@IHCDBEA??DBHDDEA@?IHGDGIFEFDBEAHEE?BEI@FGBCBDHDCABA@@HBFE@FIDI?GCEABA@CCFHF@DC@AEDHI@?GG?I
@>chr21:9911985-9912071-0
CTCATACCACGCTGCACTGCATGTTGTCAGTGGTAACGGNGAAGGGCACCTCCATGGCAGCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCNGCAGAGA
+
B?@HH@DGH@BABFAEEGI@@CFFADDHAFI@?B?@.BE#BD?HFCIDGIEFDI???GB#?FG@AEB@HIDBIA??I@CAIG@D@CGIIIII+IACCBDH
@>chr21:9911985-9912071-1
CTCATACCACGCTGCACTGCATGTTGTCAGTGGCAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGA
+
CFCD?B@F!?E??BDF?G@AHBAGH??IBBI?ECGEIDEBEA@IDGA@HECBDBDADDBBIG?BI@CFEFFFAGDB?E?EC?AIDF?DFI?IE?ICCCAG
@>chr21:9911985-9912071-2
CTCATACCACGCTGCACTGCATGTTGTCAGTGGCAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGA
+
HCIAFEGBACACHAIGBFEEGE@BDFFF@IF?FB?EAHGBG@BBGAICFI@FAA@EIGHHHEG@HFDF@G@FBD*CGA?DDA@IADCB@DEFIFHIIHAF
@>chr21:9911985-9912071-3
CGCATACCACGCTGCTGGCCCAGAAGTAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGNGCCCTTCNCCATCGCCCCTGACAACATGCAGTGCAGAGA
+
I;DH?GFE@A?GB?F?EI?FHI@BIE1DBH?CHEGADIEAAACFHED?FFHGFCEGI@FD2HICFB@C0@G@H.HFB*FFC?AEDC?@BAI@?IIDCGDA
@>chr21:9911985-9912071-4
CTCATACCACGCTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCACGGAGGTGCCCTTCTCCATTACCACTGACAACATGCAGTGCAGAGA
+
?EEID@EHBAADDAFHFDHCCBH??GGD@A?HGAGAD@C?ACIF@ECB?CCDGF#??HEED@@HHEBC??GAEADAB?EIFHGEFI@GEBDG@BHIDHHB
@>chr21:9911985-9912071-5
CTCATACCACGCTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCATTACCACTGACAACATGCAGTGCAGAGA
+
HGGIFEGIIBGD@@IEEHGDGACFECDBCEEF@C?DAIHDHGIF@EE??EF?AC@BCECFE@FCFIFGABEFEBCCAAFBCF?IFAEAG@HB@EIGA?@?
@>chr21:9911985-9912071-0
GAAGGTCCTCTGCACTGCATGTTGTCAGTGGTAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGATC
+
C?ADB?GGCHD@B?DAHGE?EIEE@IDH?*F@??GECD?AHGB@B?AGCDBH@?@DDHEDIGI?@H?H!FDHCBHD@C?@@B?@@@@EHH?HIDCG?AIH
@>chr21:9911985-9912071-1
GAAGGTCCTCTCCACTGCATGTTGTCAGTGGCAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGATC
+
E@@EAGH?GGB-CFIDF?@ADIG@@IHCICFGAEFHCE;H?ADFEFEFCGECDEFGE@BHHBIGIBFD?DAFBAHIGG@IF?G@@?@IG@?G@@E?CDC@
@>chr21:9911985-9912071-2
GAAGGTCCTCTGCACTGCATGTTGTCAGTGGCAATGGAGAAGGAAACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGATC
+
EI@ADGACHDDAF@@CICHCBEEA?AABHH@A?@H?HF@FAG?5&G?ID@IFGCACHIDBG@BG?ACIGAFH?HEICGAC?GFHD@BHGBCBHECCHGBC
@>chr21:9911985-9912071-3
GAAGGTCCTCTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCATTGCTACTGACAACATGCAGTGCAGAGATC
+
GFGGBDD??GF?GBIECIG@HABD?BEE?GEABGDBACD@EDA@@?DBADGCDACIBEEDIICFIII@DCBCI?)IHHEDA@?I?IIGGADFE@HAABGH
@>chr21:9911985-9912071-4
GAAGGTCCTCTGCTGGCCCAGAAGCAACGGCTGGAGTGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCATTACCACTGACAACATGCAGTGCAGAGATC
+
@@EHDID?@EHC@CCFCEIFIABBIGEIFBBAFG@C&GIC?IFEABBDHBDEHFA@@BGHFH??HFBIF?BGBDBDBGDCCGFG?CIEBDIDHCGFAFDI
@>chr21:9911985-9912071-5
GAAGGTCCTCTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCATTACCAATGACAACATGCAGTGCAGAGATC
+
IGBHBDF?HC?BIHEHAG?G?BAI?IG@CCF?B?HGD@FB?EHBIDEBCHFAGIDF?HHBECIEDCDBGGEDFCDB7DCGCEAEFECGBHGDFEAFE?@I
@>chr21:9911985-9912071-0
GCGGCGTACTGCACTGCNTGTTGTCAGTGGTAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGGCGTTGCTTCTGGGCCAGCAGAGATCG
+
DEHAAE@EBC@EBCFFI-DH:?DFHEIGDEAIIF?DEBGF@AD@@?@A@I@DDCB@D5@AGG?FIBBF@DABI9FCCEAG@BGBACF@DB@FGGIICECB
@>chr21:9911985-9912071-1
GCGGCGTACTGCACTGCATGTTGTCAGTGGTAATGGAGAAGGGCCCCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGATCG
+
DFH?E@BDHBI@GBED@DEFHA@CE@@EIE@C@H@G@@EHHH@F9B@DIFC@GHGA?EICA?HDHDH@DAB??CIEB@C@@GII?GADGGHHI?CCDDA@
@>chr21:9911985-9912071-2
GCGGCGTACTCCACTGCATGTTGTCAGTGGTAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGTGCTCCAGCCGTTGCTTCTGGGCCAGCAGAGCTCG
+
GBEG?@HB@C7CECBIGAH@DF@HBG@I?C?BIBDCHCGBFHHE??FFE@DBCFCB@I@DE?GCC#?GFDCEE@DB@AF?GHDCBFEDDCDAIAFG2@@B
@>chr21:9911985-9912071-3
GCGGCGTACTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCCTTACCACTGACAACATGCAGTGCAGAGATCG
+
?ICE?BDIBFHDDCBD?CE??FCGDG@IGHCHEBBAAEE?ECDEBH@HC@BBDC?GBAHEEEB@@HC@#@?B@FCIAFC?HIDEFII@F?F?@H??AIIE
@>chr21:9911985-9912071-4
GCGGCGTACTGCTGGCCCAGAANCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCATTACCACTGACAACATGCAGTGCAGAGATCG
+
DHAIH@IBBAGFG@HIGH@EEI)IDBH@ADECCGB?GEBGE@EGEICDAIHEDGF@?EGIACCHGG?BF@HIDGDDGGIFFEFAGDE?CACGIB?BCEAG
@>chr21:9911985-9912071-5
GCGGCGTACTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCAGGATGCCATGGAGGTGCCCTTCTCCATTACCACTGACAACATCCAGTGCAGAGATCG
+
A?GCA?GD?A?@CH?DCAIBHGDHD@BE@EBDBHE?GFFF@I4@IBAHGHB??C+C?@EFABABA@GBCCCG?@FF?HID@AI?F3GFAIHFEE@D@ABC
@>chr21:9911985-9912071-0
TCAGACGGTAATCTGCACTGCATGTTGTCAGTGGCAATGGAGAAGGGCACCTGCATGGCATCCAGGGCGCGCTCGAGCCGTTGCTTCTGGGCCAGCAGAG
+
EFGB?DECGA?A?IDIIIDDEHFFC?BDIDE@C?DFBCBBC@A?G@FBEEBH/?G?A@HFIBI?AGAE@HE?@F4ABEG;I@@7HCH@IAGDAFEIBCDE
@>chr21:9911985-9912071-1
TCAGACGGTAANCTGCACTGCATGATGTCAGTGGCAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCAGAG
+
?ICBH?ACCD@5HEDFDGIHIGGC(ACH@C@CG@GHI?FBDCHBIBFCHIDIIDGIDI@CCIFCGAAIDFAIBHCCHCCDEHA?I=BGF@IGFHABF?EI
@>chr21:9911985-9912071-2
TCAGACGGTAATCTGCACTGCATGTTGTCAGTGGCAATGGAGAAGGGCACCTCCATGGCATCCAGGGCGCGCTCCAGCCGTTGCTTCTGGGCCAGCTGAG
+
?CA@CEIC@?GIHI?@HADFD?D@HIHFHCDECIC@?IBE?IEHHIDHDGADCAHBIAICEGHB@CDD?CGDGBEABDGDCCCB0BBGCDFGFB@D-EFC
@>chr21:9911985-9912071-3
TCAGACGGTAATCTGCTGGCCCAGAAGCAACTGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCCTTCTCCATTTCCGCTGACAACATGCAGTGCAGAG
+
GIE?DEGH@ACEFEGIAIDEDI@HBIHCCGA4HCICBFF?EBAC?CBCIFIBEH?FHAF@@CAFIICC?DH?H@D%IE*FI@EAADICICC@BFH?IHF?
@>chr21:9911985-9912071-4
TCAGACGGTAATCTGTTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGATGCCATGGAGGTGCCGTTCTCCATTGCCACTGACAACATGCAGNGCAGAG
+
@FD?BD?BD?FDDI?$AD@C?CBCG?BD@DIGGFD@FEF@G?EDIEAADG@GDEEAH?BAEFIC@+?@AAEEGCHHFHCAHHIEHIEIGFI@H7CEHCIF
@>chr21:9911985-9912071-5
TCAGACGGTAATCTGCTGGCCCAGAAGCAACGGCTGGAGCGCGCCCTGGGTGCCATGGAGGTGCCCTTCTCCATTGCCACTGACAACATGCAGTGCAGAG
+
DHID?DAIIIEIGHBGBHED??CGFCAEBH@@FBBDBE?H?HIG?HGBB;G?BDBEH@CA?EDB@HA?HAGFHGCCIGFH=IDB?CAHHGHGGEBADF@I
@>chr21:9912107-9912215-0
ACCACTATGTCTGCAGCTCCGACTTCCAGTTGTGCGTGTCCTGCAGTCGCTCGCCCACCCTGCACGTTGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTG
+
BB@ICEF?HIFGBAG?BHDD@AC@ECGHG1BH?@CIH@@IGFCFHCA?DDHHD?EIGBHA@GIDAHBCFGHGHB?HAFGG?D@DDGH?IHDB@BD?HCBH
@>chr21:9912107-9912215-1
ACCACTATGTCTGCAGCTCCGACTTCCAGCTGTGCGTGTCCTGCAGTCGCTCGCCCACCCTGCACGTTGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTG
+
CCFEBEECB?CAHDGHGFFI@I@AB?IGEBEC?D?GIIGC?F?HGDG?C/I@HFIDE?BHGA@HE?ABHCAFHACFHHIC@HH@HA@B?G@GA?AIGBFA
@>chr21:9912107-9912215-2
ACCACTATGTCTGCAGCTCCGACTTCCAGCTGTGCGTGTCCTGCAGTCGCTCGCCCACCCTGCACGTTGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTG
+
CFCI@BBB@GI??CFF@?AII@BGD?HI?CFFAFFHGEEBA@HA?CCF@HHFCIH?GDCHEGC@H@FF?DCH5H@CEEB?DGHC?CCEAHC?AC@EDDCE
@>chr21:9912107-9912215-3
ACCACTATGTCAGCTGGCCGCAGAGACCCAGACGCTGGCACAGCCGACACAGCAAGACTCAACGTGCAGGGTGGGCGAGCGACTGCAGGACACGCACAGC
+
GCFGGBHCD@HEFBGCCEHE?EGG@ABC?D?BBCDCFA@DH?DH?@FHCIECEAEGHAI?HDDBAHAA?AHEI@DGIGGHGHH?BAECCFBCFABB@CCI
@>chr21:9912107-9912215-4
ACCACTATGTCAGCTGGCCGCAGAGACCCAGACGCTGGCACAGCCGACACAGCAAGACTCAACGTGCATGGTGGGCGAGCGACTGCAGGACACGCACAGC
+
GGBAFDFIIHBIHI?D@BF?C@EIHDEGDBFAE@@EBGB@BB@G@A@IGDE@A?BDE@HC?D@@??DG*EIEGA?GFGDCF?AI@D&IFD@HCBI@BABI
@>chr21:9912107-9912215-5
ACCACTATGTCAGCTGGCCGCAGCGACCCAGACGCTGGCACAGCCGACACAGCAAGACTCAACGTGCAGGGTGGGCGAGCGACTGCAGGACACGCACAGC
+
GH?HFHI@@G@ICGBDIG@HCDF<@CHGGBGGG?DIHE@GFBGCC@DFFD@EDGA@IDE?DHA@FICICA@I@?C"ECG@IAAI?AFFG?AIIAAIDDED
@>chr21:9912107-9912215-0
CTCATACCATGCTGCAGCTCCGACTTCCAGCTGTGCGTGTCCTGCAGTCGCTCGCCCACCCTGCACGTTGAGTCTTGCTGTCTCGGCTGTGCCAGCGNCT
+
GIABE?IEB"@GBG@EECCA@FC@D?I?EAGIHBB@FCDAACDA?EA?I?@?CDEGB?G?B@GBDCDIAI?IACAGBG?F@:IIHBFH?FGB@DCEG<@E
@>chr21:9912107-9912215-1
CTCATACCACGCTGCAGCTCCGACTTCCAGCTGTGCGTGTCCTGCAGTCGCTCGCCCATCCTGCACNTTGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCT
+
FBEDIC@?ECDBABCDDIA@DHBHGDHBF@?EF?I@AFAID@GD@@CAIEDAIBFE@@2@?HEACE&EC@DIFF?D@A@BCAEA@C@FDGBF?I@@?IHF
@>chr21:9912107-9912215-2
CTCATACCACGCTGCAGCACCGACTTCCAGCTGTGCGTGTCCTGCAGTCGCTCGCCCACCCTGCACGTTGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCT
+
HDGIAEFCEGIA?ABF@@!GEHHAF?FEDGGGGE?I?CFA@F@DCDF?DIIBCAADAED?BGEH@CIDAIAHDD?GBGEIGIEA?DCAAAEFBHBBAFII
@>chr21:9912107-9912215-3
CTCATACCACGCAGCTGGCCGCAGAGACCCAGACGCTGGCACAGCCGACACAGCAAGACTCAACGTGCAGGGTGGGCGAGCAACTGCAGGACACGCACAG
+
CHEGHDGGE@?HIGA@BFECF@CDCAE?AE??HI?FH?GACEDHHAGA?CHEDDF?DEAEFCEIH@HDDBFEEGDADHEE@/?DAGE@ECG?BIECF@CG
@>chr21:9912107-9912215-4
CTCATCCCACGCAGCTGGCCGCAGAGACCCAGACGCTGGCACAGCCGACACAGCAAGACTCAACGTGAAGGGTGGGCGAGCGACTGAAGGACACGCACAG
+
DG?AB<CGAD@DFEEFA?GC@@@IDIAF@HEDHCGC@DGGCAGFGHD@EAIDD?@C@?EBH?G@BBF(GDAAHDFBB@EHIHFICB+BBE@AH?C@EDHI
@>chr21:9912107-9912215-5
CTCATACCACGCAGCTGGCCGCAGAGACCCAGACGCTGGCACAGCCGACACAGCAAGACTCAACGTGCAGGGTGGGCGAGCGACTGCAGGACACGCACAG
+
GDFAG?DCBIAEIBDG?IA@DC0GFI?GB@DBG?I?IIB?CE?DCFAFHCHEHHE?BFHEEFACEFBDDAA@IG?GGGFDGEBDHFGDCF?BFAHDAE@G
@>chr21:9912107-9912215-0
GTAGCTCCTCTGCAGCTCCGACTTCCAGCTGTGCGTGTCCTGCAGTAGCTCGCCCACCCTGCACGTGGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTGG
+
D.DD(BADIACHACCCHI?DBDB?E@CAFGIF?HAGIFI@??DH@A4AHFAFI?BDEEEGHGGIA@DECFEBGBAIBDGHGDDHGCIIADH@BHIHCIFG
@>chr21:9912107-9912215-1
GAAGGTCCTCTGCAGCTCCGACTTCCAGCTGTGCGTGGCCTGCAGTCGCTCGACCACCCTGCACGTGGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTGG
+
IBCCHFHEDHFFGHHIHCCHAHI@B@IGF?DGEDIB@7@?@?ECDIBBB?BA+GBGHEBD@EGFAABFIGCDGFEHH@I?IGH@ICBDG?AAIEIGBI?E
@>chr21:9912107-9912215-2
GAAGGTCCTCTGCAGCTCCGACTTCCAGCTGNGCGTGTACTGCAGTCGCTCGCCCACCCTGNACGTGGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTGG
+
C@H@DEEECIB@@A?FA@GEEIBI?EADAIG!HFCFF@>CCIHDHF?GC?HFBIA?CG?DI(FHCDGHBDBGEGHGADFA@IFGDHHA?CACBFIFBCDF
@>chr21:9912107-9912215-3
GAAGGTCCTCAGCTGCCCGCAGAGACCCAGACGCTGGNACAGCCGACACAGCAAGACTCCACGTGCAGGGTGGGCGAGCNACTGCAGGACACGCACAGCT
+
BIFGIEBDCDI?EFF.HGAIDAG@DAIEHB?DHICFC<IDEEGIIG@BAH?GEEGIC@ADBCACEECDA?C@G?@DFIA1H?DH@CIFHBDA?DA@FGH?
@>chr21:9912107-9912215-4
GAAGGTCCTCAGCTGGCCGCAGAGACCCAGACGCTGGCACAGCCGACGCAGCAAGACTCCACGTGCAGGGTGGGCGAGCGACTGCAGGACACGCACAGCT
+
EEC@@BEGHHG?D?HCFF?I@ID@IBDDHFBBHHGEEA?EDG?CH?@(?CAHHC?ACHHC?AH@CBCBHH@HCD?ABDEBBAG?CBBBH?FFC?AAIFBB
@>chr21:9912107-9912215-5
GAAGGTCCTCAGCTGGCAGCAGAGACCCAGACGCTGGCACAGCCGACACAGCAAGANTCCACGTGCAGGGTGGGCGAGCGACTGCNGGACACGCNCAGCT
+
ED?C@GHB??BGCEFEA3ICADHFB?AFIG?HIDG?HEFF?BHBHEDADCBDCDAH(AIGIEBI@CAADA@HBEH?I@BFIEFAE9FFEAEI?E%AE?@I
@>chr21:9912107-9912215-0
GCGGCGTACTGCAGCTCCGACTTCCAGCTGTGCGTGTCCTGCAGTCGCTCGCCCACCCTGCACGTGGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTGGN
+
AGGCACEDDF?H@@GA?DEI?DE?BGCFBI$FHHDIHACIEFDGCBDI?DGIEFHHBI?EII@DGHBGBGB?IBCDI?BEBCBGCABEAGACFC?IDAD2
@>chr21:9912107-9912215-1
GCGGCGTACTGCAGCTCCGACTTCCAGCTGTGCGTGTCNTGCAGTCGCCCGCCCACCCTGNACGTGGAGTCTTGCTGTGTCGGCTGTGCCAGCGTCTGGG
+
@G?FAA?CCIGG@B?A?@AGAG?HB@AD?@HGC?DFID2GBGDDGA?B=@?F??@C@BHD5?@EFAHG?I?DEA@DGFABAD@?IDC??FG?CEEDFHG@