Mercurial > repos > kpbioteam > clusterprofiler_go
changeset 1:b4d956eab58d draft
Uploaded
| author | kpbioteam |
|---|---|
| date | Sun, 28 Apr 2019 07:28:12 -0400 |
| parents | d81d0f7d99a6 |
| children | bf01a06508a8 |
| files | clusterProfiler_go.xml test-data/._.DS_Store test-data/._ego.pdf test-data/._ego.txt test-data/ego.pdf test-data/ego.txt test-data/genedf.txt |
| diffstat | 7 files changed, 2309 insertions(+), 56 deletions(-) [+] |
line wrap: on
line diff
--- a/clusterProfiler_go.xml Sun Apr 28 03:43:14 2019 -0400 +++ /dev/null Thu Jan 01 00:00:00 1970 +0000 @@ -1,56 +0,0 @@ -<tool id="clusterprofiler_go" name="Cluster Profiler GO" version="0.1.0"> - <description>run GO Analysis</description> - <requirements> - <requirement type="package" version="3.6.0">bioconductor-clusterprofiler</requirement> - <requirement type="package">r-ggplot2</requirement> - <requirement type="package" version="3.5.0">bioconductor-org.hs.eg.db</requirement> - </requirements> -<command detect_errors="exit_code"><![CDATA[ - Rscript '$clusterprofiler_go_script' - ]]></command> - <configfiles> - <configfile name="clusterprofiler_go_script"><![CDATA[ - -require("clusterProfiler", quietly = TRUE) -require("org.Hs.eg.db", quietly = TRUE) -require("ggplot2", quietly = TRUE) - -gene <- read.table('$entrezid') -ego <- enrichGO(gene = c(gene\$V2), - keyType = "ENTREZID", - OrgDb = org.Hs.eg.db, - ont = "BP", - pAdjustMethod = "BH", - pvalueCutoff = 0.01, - qvalueCutoff = 0.05, - readable = TRUE) - -write.table(ego, '$table') -dotplot(ego) -ggsave(file = '$plot', device = "pdf") - - ]]> - </configfile> - </configfiles> - - <inputs> - <param type="data" name="entrezid" format="txt" /> - </inputs> - <outputs> - <data name="table" format="txt" /> - <data name="plot" format="pdf" /> - </outputs> - <tests> - <test> - <param name="entrezid" value="genedf.txt"/> - <output name="table" file="ego.txt"/> - <output name="plot" file="ego.pdf"/> - </test> - </tests> - <help><![CDATA[ - This tool provide GO Enrichment Analysis of a gene set. Given a set of genes, this will return the enrichment GO categories after FDR control. - ]]></help> - <citations> - <citation type="doi">10.1089/omi.2011.0118</citation> - </citations> -</tool> \ No newline at end of file
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/ego.txt Sun Apr 28 07:28:12 2019 -0400 @@ -0,0 +1,1272 @@ +"ID" "Description" "GeneRatio" "BgRatio" "pvalue" "p.adjust" "qvalue" "geneID" "Count" +"GO:0090662" "GO:0090662" "ATP hydrolysis coupled transmembrane transport" "39/743" "75/17381" 1.16446168869279e-33 6.02608923898516e-30 3.6159599806776e-30 "ATP6V1C1/ATP5F1/ATP12A/ATP1B3/ATP5C1/ATP5G1/ATP6V1B2/ATP2B1/ATP2A2/ATP5E/ATP6V0A1/ATP1A3/ATP2B4/ATP1B2/ATP1A1/ATP5O/ATP7A/ATP6V1B1/FXYD2/ATP6V1A/ATP5G3/ATP2B3/ATP1A2/ATP6AP1/ATP4A/ATP5D/ATP6V0C/ABCC6/ATP2A3/ATP6V0B/ATP1A4/ATP2A1/ATP1B1/ATP6V1E1/ATP2B2/ATP7B/ATP5G2/ATP5B/ATP5A1" 39 +"GO:0099132" "GO:0099132" "ATP hydrolysis coupled cation transmembrane transport" "32/743" "57/17381" 2.9113643244268e-29 7.53315518945435e-26 4.52027618792583e-26 "ATP6V1C1/ATP5F1/ATP12A/ATP5C1/ATP5G1/ATP6V1B2/ATP2B1/ATP2A2/ATP5E/ATP6V0A1/ATP2B4/ATP5O/ATP7A/ATP6V1B1/ATP6V1A/ATP5G3/ATP2B3/ATP1A2/ATP6AP1/ATP4A/ATP5D/ATP6V0C/ATP2A3/ATP6V0B/ATP1A4/ATP2A1/ATP6V1E1/ATP2B2/ATP7B/ATP5G2/ATP5B/ATP5A1" 32 +"GO:0099131" "GO:0099131" "ATP hydrolysis coupled ion transmembrane transport" "33/743" "69/17381" 4.07645049844851e-27 7.03187710982369e-24 4.21948384927127e-24 "ATP6V1C1/ATP5F1/ATP12A/ATP5C1/ATP5G1/ATP6V1B2/ATP2B1/ATP2A2/ATP5E/ATP6V0A1/ATP2B4/ATP5O/ATP7A/ATP6V1B1/ATP6V1A/ATP5G3/ATP2B3/ATP1A2/ATP6AP1/ATP4A/ATP5D/ATP6V0C/ABCC6/ATP2A3/ATP6V0B/ATP1A4/ATP2A1/ATP6V1E1/ATP2B2/ATP7B/ATP5G2/ATP5B/ATP5A1" 33 +"GO:1903522" "GO:1903522" "regulation of blood circulation" "62/743" "289/17381" 1.33489686824835e-26 1.7270228232963e-23 1.03630151614016e-23 "BDKRB2/CASQ1/CALM1/CACNB4/ADM/CACNA1C/CACNG1/AVPR1A/CALM3/AGT/ATP1B3/AVPR1B/CALCA/AKT1/ATP2B1/ASIC2/ATP2A2/ASPH/ADRA1D/ADRA1A/ATP1A3/ATP2B4/ATP1B2/ATP1A1/ADRA2B/ADORA3/CAMK2D/CAV3/ADRA2C/CALM2/CASR/BMPR2/CACNA1F/CACNA2D1/FXYD2/AGTR1/ADRA1B/ADA/ATP2B3/ADRA2A/ATP1A2/ADRB1/CACNA1S/CAV1/ATP2A3/CD38/CACNA1B/CACNA1D/ATP1A4/ATP2A1/ATP1B1/CACNB1/AGTR2/CASQ2/ATP2B2/GRK2/ANK2/AVPR2/AVP/CACNB2/CACNB3/ADORA1" 62 +"GO:0010038" "GO:0010038" "response to metal ion" "63/743" "327/17381" 2.60830375607504e-24 2.69959438753766e-21 1.61989391166765e-21 "APP/CDKN1B/ATF1/CALM1/C1QA/AQP2/CDK1/CDK4/CASP9/CALM3/FAS/ADCY1/CCNB1/AKT1/ACTA1/TSPO/BAD/BGLAP/ANXA7/AOC1/ADD1/CAMK2D/ACO1/ASCL1/BSG/ENTPD6/CALM2/CASR/ATP7A/CAPN3/ALAD/CAT/ALOX15/ATP5D/CASP8/CAV1/BCL2/AQP3/ABAT/AQP9/BRAF/ANK3/APBB1/CD14/CALR/AQP1/PARP1/CASQ2/BMP6/APOBEC1/CDH1/ATP7B/CASP3/CA2/ALOX5AP/ARG1/AANAT/BNIP3/CCND1/ATF4/ANXA11/CD86/B2M" 63 +"GO:0006164" "GO:0006164" "purine nucleotide biosynthetic process" "56/743" "260/17381" 3.30220867429573e-24 2.84815498158006e-21 1.70903782266182e-21 "ATP5F1/ALDOA/CALM1/ADM/ADRB2/ADK/CALM3/ACAT1/ADCY1/CALCA/ATP5C1/ATP5G1/ATP5E/ADCY6/ATP6V0A1/APOE/AMPD3/ADCY5/ADCY9/ADCY7/ADORA3/ATP5I/AMPD1/CALM2/ADRB3/ABCA1/ATP5O/CALCR/APLP1/ATIC/ATP5G3/ADCYAP1R1/ADA/ADRA2A/ADRB1/ATP5D/ATP5J/ADORA2B/APRT/ACR/AMPD2/AQP1/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/ATP5G2/AVPR2/AVP/AK2/ATP5B/ATP5A1/ADSL/ADCY2/ADSS" 56 +"GO:0072522" "GO:0072522" "purine-containing compound biosynthetic process" "57/743" "273/17381" 6.63681802678279e-24 4.90650475551442e-21 2.94415235774575e-21 "ATP5F1/ALDOA/CALM1/ADM/ADRB2/ADK/CALM3/ACAT1/ADCY1/CALCA/ATP5C1/ATP5G1/ATP5E/ADCY6/ATP6V0A1/APOE/AMPD3/ADCY5/ADCY9/ADCY7/ADORA3/ATP5I/AMPD1/CALM2/AMD1/ADRB3/ABCA1/ATP5O/CALCR/APLP1/ATIC/ATP5G3/ADCYAP1R1/ADA/ADRA2A/ADRB1/ATP5D/ATP5J/ADORA2B/APRT/ACR/AMPD2/AQP1/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/ATP5G2/AVPR2/AVP/AK2/ATP5B/ATP5A1/ADSL/ADCY2/ADSS" 57 +"GO:0009152" "GO:0009152" "purine ribonucleotide biosynthetic process" "55/743" "257/17381" 1.19262814877841e-23 7.71481333741034e-21 4.62928031433725e-21 "ATP5F1/ALDOA/CALM1/ADM/ADRB2/ADK/CALM3/ACAT1/ADCY1/CALCA/ATP5C1/ATP5G1/ATP5E/ADCY6/ATP6V0A1/APOE/AMPD3/ADCY5/ADCY9/ADCY7/ADORA3/ATP5I/AMPD1/CALM2/ADRB3/ABCA1/ATP5O/CALCR/APLP1/ATIC/ATP5G3/ADCYAP1R1/ADRA2A/ADRB1/ATP5D/ATP5J/ADORA2B/APRT/ACR/AMPD2/AQP1/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/ATP5G2/AVPR2/AVP/AK2/ATP5B/ATP5A1/ADSL/ADCY2/ADSS" 55 +"GO:0009260" "GO:0009260" "ribonucleotide biosynthetic process" "56/743" "270/17381" 2.36392621096328e-23 1.35925757130389e-20 8.15623663431775e-21 "ATP5F1/ALDOA/CAD/CALM1/ADM/ADRB2/ADK/CALM3/ACAT1/ADCY1/CALCA/ATP5C1/ATP5G1/ATP5E/ADCY6/ATP6V0A1/APOE/AMPD3/ADCY5/ADCY9/ADCY7/ADORA3/ATP5I/AMPD1/CALM2/ADRB3/ABCA1/ATP5O/CALCR/APLP1/ATIC/ATP5G3/ADCYAP1R1/ADRA2A/ADRB1/ATP5D/ATP5J/ADORA2B/APRT/ACR/AMPD2/AQP1/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/ATP5G2/AVPR2/AVP/AK2/ATP5B/ATP5A1/ADSL/ADCY2/ADSS" 56 +"GO:0046390" "GO:0046390" "ribose phosphate biosynthetic process" "56/743" "273/17381" 4.18533493872842e-23 2.16591083079196e-20 1.2996566388683e-20 "ATP5F1/ALDOA/CAD/CALM1/ADM/ADRB2/ADK/CALM3/ACAT1/ADCY1/CALCA/ATP5C1/ATP5G1/ATP5E/ADCY6/ATP6V0A1/APOE/AMPD3/ADCY5/ADCY9/ADCY7/ADORA3/ATP5I/AMPD1/CALM2/ADRB3/ABCA1/ATP5O/CALCR/APLP1/ATIC/ATP5G3/ADCYAP1R1/ADRA2A/ADRB1/ATP5D/ATP5J/ADORA2B/APRT/ACR/AMPD2/AQP1/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/ATP5G2/AVPR2/AVP/AK2/ATP5B/ATP5A1/ADSL/ADCY2/ADSS" 56 +"GO:1901652" "GO:1901652" "response to peptide" "72/743" "477/17381" 4.29358923225376e-21 2.01993857062847e-18 1.21206585982283e-18 "CDO1/ATP6V1C1/ANXA1/APP/CDKN1B/KLF5/CASP4/ADM/ADRB2/AVPR1A/CDK4/AKT2/AGT/AVPR1B/ADCY1/AKT1/ATP6V1B2/AGER/ADCY6/ATP6V0A1/ADCY5/ADCY9/ADCY7/ATP1A3/ACTN2/APC/CCKAR/CDC5L/BSG/AGRP/AREG/CASR/CD36/ATP6V1B1/CDC6/CACNA2D1/ATP6V1A/AGTR1/CAT/ATP6AP1/BMP7/ATP6V1G2/APRT/CAV1/ATP6V0C/BRAF/CD40/ATP6V0B/ATP6V1E1/AKR1B1/CACNB1/AGTR2/CEACAM1/CCND3/ADCY8/PARP1/ADCY3/CAV2/ZFP36L1/APOBEC1/CDK5/CA2/AVPR2/ARG1/CCNA2/AHSG/APEX1/JAG1/AANAT/ADCY2/CACNA1A/CAMK2A" 72 +"GO:0055074" "GO:0055074" "calcium ion homeostasis" "67/743" "424/17381" 8.6643497237243e-21 3.67410366722274e-18 2.20464903499763e-18 "APP/BDKRB2/ANXA6/CASQ1/CALM1/APLNR/ADM/CACNA1C/ABL2/BDKRB1/AVPR1A/CD4/CALM3/CALB1/AGT/AVPR1B/CALCA/ATP2B1/ATP2A2/C3AR1/APOE/ADRA1D/ADRA1A/ADCY5/CALCB/ATP2B4/BOK/ANXA7/CCKAR/CAMK2D/CAV3/CALM2/CASR/CD36/ATP6V1B1/CAPN3/CACNA2D1/CALB2/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ADRA1B/ATP2B3/ATP1A2/FASLG/CAV1/BCL2/CD40/CD38/CCKBR/ATP2A1/ATP1B1/CALR/CASQ2/C5AR1/ADCYAP1/ATP2B2/ATP7B/ANK2/AVP/BNIP3/CACNA1A/CACNB3/ABL1/BAK1" 67 +"GO:0006874" "GO:0006874" "cellular calcium ion homeostasis" "66/743" "413/17381" 9.22963240075277e-21 3.67410366722274e-18 2.20464903499763e-18 "APP/BDKRB2/ANXA6/CASQ1/CALM1/APLNR/ADM/CACNA1C/ABL2/BDKRB1/AVPR1A/CD4/CALM3/CALB1/AGT/AVPR1B/CALCA/ATP2B1/ATP2A2/C3AR1/APOE/ADRA1D/ADRA1A/ADCY5/CALCB/ATP2B4/BOK/ANXA7/CCKAR/CAMK2D/CAV3/CALM2/CASR/CD36/CAPN3/CACNA2D1/CALB2/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ADRA1B/ATP2B3/ATP1A2/FASLG/CAV1/BCL2/CD40/CD38/CCKBR/ATP2A1/ATP1B1/CALR/CASQ2/C5AR1/ADCYAP1/ATP2B2/ATP7B/ANK2/AVP/BNIP3/CACNA1A/CACNB3/ABL1/BAK1" 66 +"GO:1901293" "GO:1901293" "nucleoside phosphate biosynthetic process" "59/743" "339/17381" 1.59489824450826e-20 5.8954274395216e-18 3.53755625661606e-18 "ATP5F1/ALDOA/CAD/CALM1/ADM/ADRB2/ADK/CALM3/ACAT1/ADCY1/CALCA/ATP5C1/ATP5G1/ATP5E/ADCY6/ATP6V0A1/APOE/AMPD3/ADCY5/ADCY9/ADCY7/ADORA3/ATP5I/AMPD1/CALM2/ADRB3/ABCA1/ATP5O/CALCR/APLP1/ATIC/ATP5G3/ADCYAP1R1/ADA/ADRA2A/ADRB1/ATP5D/ATP5J/ADORA2B/APRT/AK1/ACR/AMPD2/AK4/AQP1/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/ATP5G2/AVPR2/AVP/AK2/ATP5B/ATP5A1/ADSL/ADCY2/ADSS" 59 +"GO:0009165" "GO:0009165" "nucleotide biosynthetic process" "58/743" "336/17381" 5.15497404423664e-20 1.77846604526164e-17 1.06717006529811e-17 "ATP5F1/ALDOA/CAD/CALM1/ADM/ADRB2/ADK/CALM3/ACAT1/ADCY1/CALCA/ATP5C1/ATP5G1/ATP5E/ADCY6/ATP6V0A1/APOE/AMPD3/ADCY5/ADCY9/ADCY7/ADORA3/ATP5I/AMPD1/CALM2/ADRB3/ABCA1/ATP5O/CALCR/APLP1/ATIC/ATP5G3/ADCYAP1R1/ADA/ADRA2A/ADRB1/ATP5D/ATP5J/ADORA2B/APRT/ACR/AMPD2/AK4/AQP1/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/ATP5G2/AVPR2/AVP/AK2/ATP5B/ATP5A1/ADSL/ADCY2/ADSS" 58 +"GO:0003018" "GO:0003018" "vascular process in circulatory system" "40/743" "162/17381" 6.81417529549149e-20 2.20395982213553e-17 1.32248796853289e-17 "BDKRB2/BBS2/ADM/ADRB2/AVPR1A/AGT/AVPR1B/CALCA/AKT1/AZU1/ACTA2/ASIC2/ADCY6/APOE/ADRA1D/ADRA1A/ABR/ADRA2B/BCR/ADRA2C/ADRB3/CASR/BMPR2/AGTR1/ADRA1B/ALOX12/ADRA2A/ATP1A2/ADRB1/ADORA2B/CAV1/CD38/AGTR2/CEACAM1/ADCYAP1/ADORA2A/AVPR2/AVP/ANGPT1/ADORA1" 40 +"GO:0072507" "GO:0072507" "divalent inorganic cation homeostasis" "68/743" "456/17381" 1.12506161996142e-19 3.42481993135313e-17 2.05506611695738e-17 "APP/BDKRB2/ANXA6/CASQ1/CALM1/APLNR/ADM/CACNA1C/ABL2/BDKRB1/AVPR1A/CD4/CALM3/CALB1/AGT/AVPR1B/CALCA/ATP2B1/ATP2A2/C3AR1/APOE/ADRA1D/ADRA1A/ADCY5/CALCB/ATP2B4/BOK/ANXA7/CCKAR/CAMK2D/CAV3/CALM2/CASR/CD36/ATP6V1B1/CAPN3/CACNA2D1/CALB2/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ADRA1B/ATP2B3/ATP1A2/FASLG/CAV1/BCL2/CD40/ANK3/CD38/CCKBR/ATP2A1/ATP1B1/CALR/CASQ2/C5AR1/ADCYAP1/ATP2B2/ATP7B/ANK2/AVP/BNIP3/CACNA1A/CACNB3/ABL1/BAK1" 68 +"GO:0019932" "GO:0019932" "second-messenger-mediated signaling" "54/743" "300/17381" 1.46323554057375e-19 4.20680217914954e-17 2.52429523081437e-17 "CASQ1/CALM1/APLNR/ADM/ADRB2/CACNA1C/AVPR1A/CD4/CALM3/AGT/ADCY1/CALCA/AZU1/ATP2A2/ADCY6/APOE/ADRA1D/BTK/ADRA1A/ADCY5/ADCY9/ADCY7/ATP2B4/ADRA2B/CD3E/CAMK2D/ADGRB2/ADRA2C/CALM2/ADRB3/CD36/CDC34/CALCR/ACTN3/ADCYAP1R1/AGTR1/ADRA1B/ADA/CD8A/ADRA2A/ATP1A2/ADRB1/ADORA2B/ATP1B1/AGTR2/BST1/ADCY8/ADCY3/CASQ2/ADCYAP1/ADORA2A/ANK2/CDH13/ADCY2" 54 +"GO:0072503" "GO:0072503" "cellular divalent inorganic cation homeostasis" "66/743" "438/17381" 2.29005448805381e-19 6.2373852503571e-17 3.74274833227632e-17 "APP/BDKRB2/ANXA6/CASQ1/CALM1/APLNR/ADM/CACNA1C/ABL2/BDKRB1/AVPR1A/CD4/CALM3/CALB1/AGT/AVPR1B/CALCA/ATP2B1/ATP2A2/C3AR1/APOE/ADRA1D/ADRA1A/ADCY5/CALCB/ATP2B4/BOK/ANXA7/CCKAR/CAMK2D/CAV3/CALM2/CASR/CD36/CAPN3/CACNA2D1/CALB2/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ADRA1B/ATP2B3/ATP1A2/FASLG/CAV1/BCL2/CD40/CD38/CCKBR/ATP2A1/ATP1B1/CALR/CASQ2/C5AR1/ADCYAP1/ATP2B2/ATP7B/ANK2/AVP/BNIP3/CACNA1A/CACNB3/ABL1/BAK1" 66 +"GO:0008016" "GO:0008016" "regulation of heart contraction" "48/743" "242/17381" 2.55493782390614e-19 6.61090161935713e-17 3.96687714764374e-17 "CASQ1/CALM1/CACNB4/ADM/CACNA1C/CACNG1/AVPR1A/CALM3/AGT/ATP1B3/CALCA/ATP2B1/ATP2A2/ASPH/ADRA1A/ATP1A3/ATP2B4/ATP1B2/ATP1A1/ADORA3/CAMK2D/CAV3/CALM2/CACNA1F/CACNA2D1/FXYD2/ADRA1B/ADA/ATP2B3/ATP1A2/ADRB1/CACNA1S/CAV1/ATP2A3/CACNA1B/CACNA1D/ATP1A4/ATP2A1/ATP1B1/CACNB1/AGTR2/CASQ2/ATP2B2/GRK2/ANK2/CACNB2/CACNB3/ADORA1" 48 +"GO:0035296" "GO:0035296" "regulation of tube diameter" "35/743" "132/17381" 1.22226004240388e-18 2.87508896338186e-16 1.72519958138347e-16 "BDKRB2/BBS2/ADM/ADRB2/AVPR1A/AGT/AVPR1B/CALCA/AKT1/ACTA2/ASIC2/ADCY6/APOE/ADRA1D/ADRA1A/ADRA2B/ADRA2C/ADRB3/CASR/BMPR2/AGTR1/ADRA1B/ALOX12/ADRA2A/ATP1A2/ADRB1/ADORA2B/CAV1/CD38/AGTR2/ADCYAP1/ADORA2A/AVPR2/AVP/ADORA1" 35 +"GO:0097746" "GO:0097746" "regulation of blood vessel diameter" "35/743" "132/17381" 1.22226004240388e-18 2.87508896338186e-16 1.72519958138347e-16 "BDKRB2/BBS2/ADM/ADRB2/AVPR1A/AGT/AVPR1B/CALCA/AKT1/ACTA2/ASIC2/ADCY6/APOE/ADRA1D/ADRA1A/ADRA2B/ADRA2C/ADRB3/CASR/BMPR2/AGTR1/ADRA1B/ALOX12/ADRA2A/ATP1A2/ADRB1/ADORA2B/CAV1/CD38/AGTR2/ADCYAP1/ADORA2A/AVPR2/AVP/ADORA1" 35 +"GO:0060047" "GO:0060047" "heart contraction" "50/743" "272/17381" 1.34874018759014e-18 3.03466542207782e-16 1.82095357134596e-16 "CASQ1/CALM1/CACNB4/ADM/CACNA1C/CACNG1/AVPR1A/CALM3/AGT/ATP1B3/CALCA/ATP2B1/ATP2A2/ASPH/ADRA1A/ATP1A3/ATP2B4/ATP1B2/ATP1A1/ADORA3/CAMK2D/CAV3/CALM2/CACNA1F/CACNA2D1/FXYD2/CDC42/ADRA1B/ADA/ATP2B3/ATP1A2/ADRB1/CACNA1S/CAV1/ATP2A3/CACNA1B/CACNA1D/ATP1A4/ACTC1/ATP2A1/ATP1B1/CACNB1/AGTR2/CASQ2/ATP2B2/GRK2/ANK2/CACNB2/CACNB3/ADORA1" 50 +"GO:0003015" "GO:0003015" "heart process" "50/743" "276/17381" 2.56549292662608e-18 5.53184412303748e-16 3.31938777787146e-16 "CASQ1/CALM1/CACNB4/ADM/CACNA1C/CACNG1/AVPR1A/CALM3/AGT/ATP1B3/CALCA/ATP2B1/ATP2A2/ASPH/ADRA1A/ATP1A3/ATP2B4/ATP1B2/ATP1A1/ADORA3/CAMK2D/CAV3/CALM2/CACNA1F/CACNA2D1/FXYD2/CDC42/ADRA1B/ADA/ATP2B3/ATP1A2/ADRB1/CACNA1S/CAV1/ATP2A3/CACNA1B/CACNA1D/ATP1A4/ACTC1/ATP2A1/ATP1B1/CACNB1/AGTR2/CASQ2/ATP2B2/GRK2/ANK2/CACNB2/CACNB3/ADORA1" 50 +"GO:0050880" "GO:0050880" "regulation of blood vessel size" "35/743" "140/17381" 9.46065379001011e-18 1.95835533453209e-15 1.17511278654862e-15 "BDKRB2/BBS2/ADM/ADRB2/AVPR1A/AGT/AVPR1B/CALCA/AKT1/ACTA2/ASIC2/ADCY6/APOE/ADRA1D/ADRA1A/ADRA2B/ADRA2C/ADRB3/CASR/BMPR2/AGTR1/ADRA1B/ALOX12/ADRA2A/ATP1A2/ADRB1/ADORA2B/CAV1/CD38/AGTR2/ADCYAP1/ADORA2A/AVPR2/AVP/ADORA1" 35 +"GO:0051480" "GO:0051480" "regulation of cytosolic calcium ion concentration" "53/743" "318/17381" 1.08929523764155e-17 2.16811648261347e-15 1.3009801421225e-15 "BDKRB2/CASQ1/CALM1/APLNR/ADM/CACNA1C/ABL2/BDKRB1/AVPR1A/CD4/CALM3/CALB1/AGT/AVPR1B/CALCA/ATP2B1/C3AR1/ADRA1D/ADRA1A/ADCY5/ATP2B4/BOK/CCKAR/CAMK2D/CAV3/CALM2/CD36/CAPN3/CACNA2D1/CALB2/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ADRA1B/ATP2B3/ATP1A2/FASLG/CAV1/BCL2/CD38/CCKBR/CASQ2/C5AR1/ADCYAP1/ATP2B2/ANK2/AVP/CACNA1A/CACNB3/ABL1/BAK1" 53 +"GO:0035150" "GO:0035150" "regulation of tube size" "35/743" "141/17381" 1.20840282703551e-17 2.31610541848472e-15 1.38978102914415e-15 "BDKRB2/BBS2/ADM/ADRB2/AVPR1A/AGT/AVPR1B/CALCA/AKT1/ACTA2/ASIC2/ADCY6/APOE/ADRA1D/ADRA1A/ADRA2B/ADRA2C/ADRB3/CASR/BMPR2/AGTR1/ADRA1B/ALOX12/ADRA2A/ATP1A2/ADRB1/ADORA2B/CAV1/CD38/AGTR2/ADCYAP1/ADORA2A/AVPR2/AVP/ADORA1" 35 +"GO:0010959" "GO:0010959" "regulation of metal ion transport" "56/743" "356/17381" 1.90606419373646e-17 3.49377394261174e-15 2.09644203014587e-15 "CASQ1/CALM1/APLNR/CACNB4/ADRB2/CACNA1C/BDKRB1/CD4/CAMK2B/CALM3/AGT/ATP1B3/AKT1/TSPO/ARF1/ACTN2/ATP2B4/ATP1B2/ATP1A1/CAMK2D/CAV3/CALM2/CASR/ATP7A/CAPN3/CACNA2D1/CALCR/FXYD2/BAX/ADCYAP1R1/CD19/ADRA2A/ATP1A2/CAMK2G/ARRB2/CAV1/BCL2/ANK3/CACNA1B/CACNA1D/ATP1B1/CACNB1/CD63/CASQ2/ADCYAP1/ADORA2A/ACTN4/ANK2/CACNB2/ATF4/CACNB3/CAMK2A/ABL1/B2M/BAK1/ADORA1" 56 +"GO:0061337" "GO:0061337" "cardiac conduction" "35/743" "143/17381" 1.95786365866165e-17 3.49377394261174e-15 2.09644203014587e-15 "CASQ1/CALM1/CACNB4/CACNA1C/CACNG1/CALM3/AGT/ATP1B3/ATP2B1/ATP2A2/ASPH/ATP1A3/ATP2B4/ATP1B2/ATP1A1/CAMK2D/CALM2/CACNA1F/CACNA2D1/FXYD2/ATP2B3/ATP1A2/CACNA1S/CAV1/ATP2A3/CACNA1D/ATP1A4/ATP2A1/ATP1B1/CACNB1/CASQ2/ATP2B2/ANK2/CACNB2/CACNB3" 35 +"GO:0009127" "GO:0009127" "purine nucleoside monophosphate biosynthetic process" "25/743" "71/17381" 6.17658750163382e-17 1.03109162325661e-14 6.18707406785052e-15 "ATP5F1/ALDOA/ADK/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/AMPD3/ATP5I/AMPD1/ATP5O/ATIC/ATP5G3/ADA/ATP5D/ATP5J/APRT/AMPD2/PARP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 25 +"GO:0009168" "GO:0009168" "purine ribonucleoside monophosphate biosynthetic process" "25/743" "71/17381" 6.17658750163382e-17 1.03109162325661e-14 6.18707406785052e-15 "ATP5F1/ALDOA/ADK/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/AMPD3/ATP5I/AMPD1/ATP5O/ATIC/ATP5G3/ADA/ATP5D/ATP5J/APRT/AMPD2/PARP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 25 +"GO:0048871" "GO:0048871" "multicellular organismal homeostasis" "54/743" "343/17381" 7.04118657082922e-17 1.13869189075129e-14 6.83273038945599e-15 "BBS2/AQP2/ADRB2/ADCY1/CALCA/ALB/ACP5/CDH3/ADCY6/AMPD3/ADCY5/ADCY9/ADCY7/CD34/BGLAP/ACACA/SERPINA3/ADD1/ADRB3/AQP4/BBS4/CD36/CD7/BAX/ACTB/ALOX12/BBS1/ATP6AP1/ADRB1/ACTG1/AZGP1/BCL2/AQP3/ABAT/BARD1/ACADVL/CD38/ACADL/ACACB/AKR1B1/AMPD2/AQP1/ALOX12B/ADCY8/ADCY3/BMP6/ABCA4/CA2/AVPR2/AVP/ADAM8/ADCY2/B2M/ADORA1" 54 +"GO:1901653" "GO:1901653" "cellular response to peptide" "54/743" "345/17381" 9.13553962265019e-17 1.43261871355196e-14 8.5964407932434e-15 "ATP6V1C1/APP/KLF5/CASP4/ADRB2/CDK4/AKT2/AGT/ADCY1/AKT1/ATP6V1B2/ADCY6/ATP6V0A1/ADCY5/ADCY9/ADCY7/ATP1A3/ACTN2/APC/CDC5L/CASR/CD36/ATP6V1B1/CDC6/CACNA2D1/ATP6V1A/AGTR1/ATP6AP1/ATP6V1G2/APRT/CAV1/ATP6V0C/ATP6V0B/ATP6V1E1/AKR1B1/CACNB1/AGTR2/CEACAM1/CCND3/ADCY8/PARP1/ADCY3/CAV2/ZFP36L1/APOBEC1/CDK5/CA2/ARG1/CCNA2/AHSG/APEX1/ADCY2/CACNA1A/CAMK2A" 54 +"GO:0050727" "GO:0050727" "regulation of inflammatory response" "57/743" "385/17381" 1.65212301251337e-16 2.51462840875196e-14 1.50890491854936e-14 "CFB/ANXA1/BIRC2/CASP1/C4BPA/C2/C8A/CASP4/C8G/C1QA/CD6/C6/AGT/CD47/AGER/ACP5/C1S/C3AR1/APOE/BTK/CD81/CASP5/ABR/BCR/C5/C1R/A2M/APOA1/CD19/AGTR1/ADA/C1QB/C8B/C7/ADORA2B/XIAP/BCL6/C4BPB/C3/C9/BST1/BIRC3/C5AR1/ADCYAP1/ADORA2A/APOD/C4B/C1QC/C4A/CD59/AHSG/CD28/ADAM8/APCS/C1QBP/SERPING1/ADORA1" 57 +"GO:0044282" "GO:0044282" "small molecule catabolic process" "56/743" "375/17381" 2.08272113419738e-16 3.07945196270613e-14 1.84782777319768e-14 "CDO1/BCAT1/ALDOC/ALDOA/KYAT1/ALDH7A1/AHCY/ENTPD5/SCARB1/ACOX1/AKT2/ACAT1/ACAT2/AKT1/ALDH1B1/APOE/ENTPD3/BAD/ATP2B4/AMT/AUH/ASPA/ABCD2/ENTPD6/ACADM/ALDH3A2/ACADSB/BLMH/ACTN3/CBS/BPGM/ADH7/ADH5/BCKDHA/ABAT/ACADVL/BCAT2/ADH4/ALDH3B1/ALDH1A1/ACADL/ALDOB/ALDH3B2/BDH1/ACACB/ENTPD2/ACAA1/ENTPD1/ALDH2/CD44/ACADS/ARG1/BCKDHB/ABCD1/AGXT/CBR3" 56 +"GO:1903779" "GO:1903779" "regulation of cardiac conduction" "25/743" "75/17381" 2.7715008831775e-16 3.98403251956766e-14 2.39062210683439e-14 "CASQ1/CALM1/CALM3/AGT/ATP1B3/ATP2B1/ATP2A2/ASPH/ATP1A3/ATP2B4/ATP1B2/ATP1A1/CAMK2D/CALM2/FXYD2/ATP2B3/ATP1A2/CAV1/ATP2A3/ATP1A4/ATP2A1/ATP1B1/CASQ2/ATP2B2/ANK2" 25 +"GO:0051384" "GO:0051384" "response to glucocorticoid" "34/743" "147/17381" 3.63436450854984e-16 5.08319900857984e-14 3.0501778948e-14 "CDO1/ANXA1/ALPL/ADM/AIF1/AVPR1A/CASP9/FAS/KLF9/BCHE/ATP2B1/BAD/BGLAP/AREG/CALCR/ALAD/ANXA3/ABCA3/CDKN1A/ZFP36L2/BCL2/APOA2/AGTR2/AQP1/BMP6/ZFP36L1/AGL/ADCYAP1/ALDH3A1/CASP3/ARG1/AANAT/CCND1/AGXT" 34 +"GO:0009156" "GO:0009156" "ribonucleoside monophosphate biosynthetic process" "26/743" "83/17381" 3.95939205010652e-16 5.25380868187211e-14 3.15255237457874e-14 "ATP5F1/ALDOA/CAD/ADK/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/AMPD3/ATP5I/AMPD1/ATP5O/ATIC/ATP5G3/ADA/ATP5D/ATP5J/APRT/AMPD2/PARP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 26 +"GO:0030819" "GO:0030819" "positive regulation of cAMP biosynthetic process" "26/743" "83/17381" 3.95939205010652e-16 5.25380868187211e-14 3.15255237457874e-14 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 26 +"GO:0010248" "GO:0010248" "establishment or maintenance of transmembrane electrochemical gradient" "12/743" "13/17381" 4.27144213387585e-16 5.52617826070188e-14 3.31598797235099e-14 "ATP12A/ATP1B3/ATP1A3/ATP1B2/ATP1A1/FXYD2/BAX/ATP1A2/ATP4A/ATP1A4/ATP1B1/BAK1" 12 +"GO:0048545" "GO:0048545" "response to steroid hormone" "57/743" "394/17381" 4.76797912346095e-16 6.01811999119767e-14 3.61117802675477e-14 "CDO1/ANXA1/ALPL/ADM/AIF1/AVPR1A/CASP9/FAS/KLF9/BCHE/ATP2B1/ABCA2/ACTA1/TSPO/RUNX1/CDK7/BAD/AR/ATP1A3/NR0B1/BGLAP/ATP1A1/AREG/CALCR/ALAD/ATP1A2/BMP7/ANXA3/ABCA3/CDKN1A/CCNE1/ZFP36L2/ARRB2/CAV1/BCL2/CD38/CBFB/ACR/APOA2/AGTR2/CALR/AQP1/PARP1/ARNTL/BMP6/ZFP36L1/AGL/ADCYAP1/ALDH3A1/CASP3/BRCA1/CA2/ARG1/AANAT/BMP4/CCND1/AGXT" 57 +"GO:0032844" "GO:0032844" "regulation of homeostatic process" "63/743" "473/17381" 7.5392084129912e-16 9.28938179457844e-14 5.57410145822658e-14 "ANXA1/CASQ1/CALM1/APLNR/ATR/ATRX/CACNA1C/BDKRB1/AVPR1A/CD4/CDK6/CALM3/CD74/AGT/CALCA/ACVR1B/TSPO/ARRB1/ARNT/ADCY5/BAD/BGLAP/BOK/CAMK2D/CAV3/CALM2/CD36/CAPN3/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ALOX12/ADA/ADRA2A/ATP1A2/FASLG/ATP6AP1/CCT6A/CAV1/BCL2/ABAT/ANK3/CD38/CCK/AGTR2/ATM/PARP1/CASQ2/ZFP36L1/ADORA2A/ACVR2A/ANK2/CA2/CA7/AVPR2/AVP/ADAM8/ABL1/B2M/BAK1/ADORA1" 63 +"GO:0007204" "GO:0007204" "positive regulation of cytosolic calcium ion concentration" "47/743" "285/17381" 1.23234549400014e-15 1.4831134724304e-13 8.89943502399122e-14 "BDKRB2/CASQ1/CALM1/APLNR/ADM/CACNA1C/ABL2/BDKRB1/AVPR1A/CD4/CALM3/AGT/AVPR1B/CALCA/C3AR1/ADRA1D/ADRA1A/ADCY5/ATP2B4/CCKAR/CAMK2D/CAV3/CALM2/CD36/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ADRA1B/ATP1A2/FASLG/CAV1/BCL2/CD38/CCKBR/CASQ2/C5AR1/ADCYAP1/ANK2/AVP/CACNA1A/CACNB3/ABL1/BAK1" 47 +"GO:0031960" "GO:0031960" "response to corticosteroid" "35/743" "162/17381" 1.2702385038056e-15 1.49397369481681e-13 8.96460188092468e-14 "CDO1/ANXA1/ALPL/ADM/AIF1/AVPR1A/CASP9/FAS/KLF9/BCHE/ATP2B1/BAD/BGLAP/AREG/CALCR/ALAD/ANXA3/ABCA3/CDKN1A/ZFP36L2/BCL2/APOA2/AGTR2/AQP1/PARP1/BMP6/ZFP36L1/AGL/ADCYAP1/ALDH3A1/CASP3/ARG1/AANAT/CCND1/AGXT" 35 +"GO:0009991" "GO:0009991" "response to extracellular stimulus" "61/743" "457/17381" 2.01155685620197e-15 2.31329038463227e-13 1.38809186568323e-13 "ALPL/BBS2/C2/ADM/AIF1/AQP2/ADRB2/AXL/AES/AHCY/AVPR1A/CD4/FAS/CDKN2D/ACAT1/AKT1/BCHE/ALB/ATP2B1/ACTA1/TSPO/APOE/BGLAP/CD3E/SERPINC1/AOC1/CCKAR/ASCL1/ADRB3/ABCA1/BBS4/CASR/BMPR2/ALAD/APOA1/CBS/CAT/ADA/BMP7/ADRB1/CDKN2B/CDKN1A/ADORA2B/BCL2/AQP3/ATF3/CD40/CCK/ACACB/ARSB/AGL/ADCYAP1/ALDH3A1/ASNS/ARG1/APAF1/ADSL/CCND1/ATF4/CBL/ASGR1" 61 +"GO:0042493" "GO:0042493" "response to drug" "57/743" "411/17381" 3.21449287842152e-15 3.61630448822421e-13 2.16996658840812e-13 "ANXA1/APOC2/CDKN1B/ATR/CDK1/CDK4/ADCY1/CCNB1/BCHE/ABCA2/CA9/CDH3/TSPO/ARRB1/ADRA1A/BAD/ATP1A3/BGLAP/ATP1A1/CD69/AOC1/PARP4/ABCA1/AMH/ALAD/CDK9/BLMH/ADCYAP1R1/APOA1/CAT/ADA/ABCA3/CDKN1A/BCL2/ABAT/BRAF/ABCC6/CD38/ACTC1/ACACB/APOA2/AK4/CALR/AQP1/ADORA2A/APOBEC1/CDH1/ALDH3A1/APOD/PLIN2/CASP3/ARG1/APEX1/CCND1/CD86/B2M/BAK1" 57 +"GO:0003014" "GO:0003014" "renal system process" "29/743" "114/17381" 3.77246360145698e-15 4.15372322075316e-13 2.49244515661771e-13 "ADM/AQP2/AVPR1A/FAS/AGT/ADCY1/ADCY6/ADRA1A/ADCY5/ADCY9/ADCY7/CD34/BCR/AQP4/AGTR1/BCL2/AQP3/BTC/AKR1B1/AGTR2/AQP1/ADCY8/ADCY3/ADORA2A/AVPR2/AVP/ADCY2/BMP4/ADORA1" 29 +"GO:0043270" "GO:0043270" "positive regulation of ion transport" "42/743" "241/17381" 5.78053939718257e-15 6.23214403758746e-13 3.7396033380896e-13 "CASQ1/CALM1/APLNR/ADRB2/BDKRB1/AVPR1A/CD4/CALM3/AGT/ATP1B3/AKT1/TSPO/APOE/ARF1/ACTN2/ATP1B2/CALM2/CASR/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ADRA2A/ARRB2/CAV1/ABAT/ANK3/CACNA1D/CCK/ATP1B1/ADORA2A/ACTN4/ANK2/AVP/CACNB2/CAMK2A/ABL1/B2M/BAK1/ADORA1" 42 +"GO:2000021" "GO:2000021" "regulation of ion homeostasis" "39/743" "210/17381" 6.28632382989808e-15 6.60530469395823e-13 3.96351870779085e-13 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/AVPR1A/CD4/CALM3/AGT/TSPO/BOK/CAMK2D/CAV3/CALM2/CAPN3/CALCR/BAX/ADCYAP1R1/CD19/AGTR1/ALOX12/ATP1A2/FASLG/CAV1/BCL2/ANK3/CCK/AGTR2/PARP1/CASQ2/ADORA2A/ANK2/CA2/CA7/AVPR2/AVP/ABL1/BAK1/ADORA1" 39 +"GO:0030816" "GO:0030816" "positive regulation of cAMP metabolic process" "26/743" "92/17381" 6.44984042180679e-15 6.60530469395823e-13 3.96351870779085e-13 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 26 +"GO:0035637" "GO:0035637" "multicellular organismal signaling" "38/743" "200/17381" 6.5095756404226e-15 6.60530469395823e-13 3.96351870779085e-13 "CASQ1/CALM1/CACNB4/CACNA1C/CACNG1/AVPR1A/CALM3/AGT/ATP1B3/ATP2B1/ATP2A2/ASPH/ATP1A3/ATP2B4/ATP1B2/ATP1A1/CAMK2D/CALM2/CACNA1F/CACNA2D1/FXYD2/ATP2B3/ATP1A2/CACNA1S/CAV1/ATP2A3/ANK3/CACNA1D/ATP1A4/ATP2A1/ATP1B1/CACNB1/CASQ2/ATP2B2/ANK2/AVP/CACNB2/CACNB3" 38 +"GO:2000257" "GO:2000257" "regulation of protein activation cascade" "28/743" "108/17381" 6.66778149654444e-15 6.63572485473413e-13 3.98177235117532e-13 "CFB/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/CD81/SERPINC1/C5/C1R/A2M/CD19/C1QB/C8B/C7/C4BPB/C3/C9/C5AR1/C4B/C1QC/C4A/CD59/C1QBP/SERPING1" 28 +"GO:0009124" "GO:0009124" "nucleoside monophosphate biosynthetic process" "26/743" "93/17381" 8.59676534302908e-15 8.27381959716026e-13 4.96471249664333e-13 "ATP5F1/ALDOA/CAD/ADK/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/AMPD3/ATP5I/AMPD1/ATP5O/ATIC/ATP5G3/ADA/ATP5D/ATP5J/APRT/AMPD2/PARP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 26 +"GO:0030804" "GO:0030804" "positive regulation of cyclic nucleotide biosynthetic process" "27/743" "101/17381" 8.89055563602909e-15 8.27381959716026e-13 4.96471249664333e-13 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 27 +"GO:0051899" "GO:0051899" "membrane depolarization" "27/743" "101/17381" 8.89055563602909e-15 8.27381959716026e-13 4.96471249664333e-13 "CASP1/CACNB4/CACNA1C/TSPO/BOK/CAMK2D/CAV3/CACNA1F/CACNA2D1/ALOX12/ATP1A2/CACNA1S/CAV1/BCL2/ANK3/CACNA1B/CACNA1D/CCK/HCN2/PARP1/ADORA2A/CACNA1E/ANK2/CACNB2/CACNA1A/CACNB3/ABL1" 27 +"GO:0006816" "GO:0006816" "calcium ion transport" "56/743" "408/17381" 8.95331202784492e-15 8.27381959716026e-13 4.96471249664333e-13 "ANXA6/CASQ1/CALM1/APLNR/CACNB4/CACNA1C/CACNG1/BDKRB1/CD4/CAMK2B/CALM3/AGT/ATP2B1/ATP2A2/TSPO/ADRA1A/ATP2B4/CAMK2D/CAV3/CALM2/CASR/CACNA1F/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ATP2B3/ADRA2A/ATP1A2/FASLG/CAMK2G/CACNA1S/ARRB2/CAV1/BCL2/ATP2A3/CACNA1B/CACNA1D/ATP2A1/ATP1B1/CACNB1/ASIC1/CASQ2/ADORA2A/ATP2B2/CACNA1E/ANK2/CDK5/CACNB2/CACNA1A/CACNB3/CAMK2A/ABL1/BAK1" 56 +"GO:0045981" "GO:0045981" "positive regulation of nucleotide metabolic process" "32/743" "145/17381" 1.12940960791397e-14 1.00770598637152e-12 6.04674835453033e-13 "CALM1/ADM/ADRB2/CDK1/ENTPD5/CALM3/ADCY1/CALCA/CCNB1/ADCY6/APOE/ARNT/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ACTN3/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 32 +"GO:1900544" "GO:1900544" "positive regulation of purine nucleotide metabolic process" "32/743" "145/17381" 1.12940960791397e-14 1.00770598637152e-12 6.04674835453033e-13 "CALM1/ADM/ADRB2/CDK1/ENTPD5/CALM3/ADCY1/CALCA/CCNB1/ADCY6/APOE/ARNT/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ACTN3/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 32 +"GO:0055067" "GO:0055067" "monovalent inorganic cation homeostasis" "32/743" "147/17381" 1.70470149837455e-14 1.48456771029052e-12 8.90816119065761e-13 "ATP6V1C1/ATP12A/AVPR1A/AGT/ATP1B3/ATP6V1B2/ATP6V0A1/ATP1A3/ATP1B2/ATP1A1/ATP6V1B1/ATP6V1A/AGTR1/ATP1A2/FASLG/ATP6AP1/ATP6V1G2/C7/ATP6V0C/BCL2/ATP6V0B/ATP1A4/ATP1B1/ATP6V1E1/AGTR2/ADORA2A/CA2/CA7/AVPR2/AVP/ATP5B/ADORA1" 32 +"GO:0007189" "GO:0007189" "adenylate cyclase-activating G-protein coupled receptor signaling pathway" "22/743" "66/17381" 1.72123792497452e-14 1.48456771029052e-12 8.90816119065761e-13 "ADRB2/ADCY1/CALCA/ADCY6/ADRA1D/ADRA1A/ADCY5/ADCY9/ADCY7/ADRA2B/ADRA2C/ADRB3/CALCR/ADRA1B/ADRA2A/ADRB1/ADORA2B/ADCY8/ADCY3/ADCYAP1/ADORA2A/ADCY2" 22 +"GO:0045762" "GO:0045762" "positive regulation of adenylate cyclase activity" "19/743" "47/17381" 1.75025641901165e-14 1.48484868334185e-12 8.90984717184535e-13 "ADRB2/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/ADRB3/CALCR/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2" 19 +"GO:0007190" "GO:0007190" "activation of adenylate cyclase activity" "17/743" "36/17381" 1.78240918077039e-14 1.4877366952398e-12 8.9271767118381e-13 "ADRB2/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/ADRB3/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/AVPR2/ADCY2" 17 +"GO:1904029" "GO:1904029" "regulation of cyclin-dependent protein kinase activity" "25/743" "88/17381" 1.87598239054874e-14 1.54098553509361e-12 9.24669682893698e-13 "CCNC/CDKN1B/CDC25C/CCNH/CDKN2D/CCNB1/AKT1/CCND2/CDK7/APC/CCNT1/CCNG1/CDC6/CDKN2B/CDKN1A/CCNT2/BLM/CCND3/CDKN1C/CASP3/CDKN2A/CDC25A/CDKN3/CCND1/CDKN2C" 25 +"GO:0042110" "GO:0042110" "T cell activation" "60/743" "467/17381" 1.98695884578374e-14 1.56978040259008e-12 9.41948067661478e-13 "ANXA1/AIF1/CD6/CD3G/CD4/CDK6/ARG2/FAS/CD74/RHOH/AKT1/CD47/AGER/RUNX1/RUNX2/CD80/CD8B/BAD/CD247/CD3E/CD27/AIRE/ATP7A/CD3D/PRDM1/CD7/CDC42/BAX/ADA/CD8A/CD1C/ZFP36L2/CD151/CASP8/CAV1/BCL2/TNFSF8/BRAF/BCL6/CBFB/BCL3/CD2/BMX/CEACAM1/CCND3/ZFP36L1/CAMK4/ADORA2A/CASP3/CD5/CD59/ARG1/CD28/ADAM8/CD1D/CD40LG/BMP4/CD86/ABL1/B2M" 60 +"GO:0016485" "GO:0016485" "protein processing" "47/743" "306/17381" 1.99293832779239e-14 1.56978040259008e-12 9.41948067661478e-13 "CFB/BIRC2/CASP1/C4BPA/C2/C8A/C8G/C1QA/C6/AGT/C1S/ASPH/C3AR1/CD81/BAD/BGLAP/CAST/CASP2/C5/C1R/A2M/CD19/C1QB/C8B/C7/XIAP/CASP8/C4BPB/C3/APOH/C9/BIRC3/PARP1/C5AR1/AEBP1/CAPN2/C4B/CASP3/C1QC/BIRC5/C4A/CD59/ADAM8/ADAM10/C1QBP/SERPING1/BAK1" 47 +"GO:0042391" "GO:0042391" "regulation of membrane potential" "55/743" "403/17381" 2.00203877431779e-14 1.56978040259008e-12 9.41948067661478e-13 "APP/BNIP3L/CASP1/CACNB4/BID/ADRB2/CACNA1C/AKT2/ATP1B3/AKT1/ASIC2/ATP2A2/TSPO/ADRA1A/BAD/ATP1A3/ACTN2/ATP1B2/ATP1A1/BOK/CAMK2D/CAV3/CACNA1F/CACNA2D1/BAX/ALOX12/ATP1A2/CACNA1S/CAV1/BCL2/ABAT/ANK3/CACNA1B/CACNA1D/ATP1A4/CCK/ATP1B1/HCN2/ASIC1/PARP1/CASQ2/ADCYAP1/ADORA2A/CACNA1E/ANK2/CDK5/CBLN1/BCL2L1/BNIP3/CACNB2/CACNA1A/CACNB3/ABL1/BAK1/ADORA1" 55 +"GO:0019229" "GO:0019229" "regulation of vasoconstriction" "21/743" "60/17381" 2.22401040907909e-14 1.71779908462452e-12 1.03076680389369e-12 "BDKRB2/ADM/AVPR1A/AGT/AVPR1B/AKT1/ASIC2/ADRA1D/ADRA1A/ADRA2B/ADRA2C/CASR/BMPR2/AGTR1/ADRA1B/ADRA2A/ATP1A2/CAV1/CD38/AVPR2/AVP" 21 +"GO:0015988" "GO:0015988" "energy coupled proton transmembrane transport, against electrochemical gradient" "15/743" "27/17381" 2.72822479053951e-14 2.04616859290463e-12 1.22780520703151e-12 "ATP6V1C1/ATP5G1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/ATP5G3/ATP1A2/ATP6AP1/ATP4A/ATP6V0C/ATP6V0B/ATP1A4/ATP6V1E1/ATP5G2" 15 +"GO:0015991" "GO:0015991" "ATP hydrolysis coupled proton transport" "15/743" "27/17381" 2.72822479053951e-14 2.04616859290463e-12 1.22780520703151e-12 "ATP6V1C1/ATP5G1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/ATP5G3/ATP1A2/ATP6AP1/ATP4A/ATP6V0C/ATP6V0B/ATP1A4/ATP6V1E1/ATP5G2" 15 +"GO:0019935" "GO:0019935" "cyclic-nucleotide-mediated signaling" "28/743" "114/17381" 2.96461635796777e-14 2.19169852178331e-12 1.31513056481277e-12 "APLNR/ADM/ADRB2/ADCY1/CALCA/ADCY6/APOE/ADRA1D/ADRA1A/ADCY5/ADCY9/ADCY7/ADRA2B/ADRA2C/ADRB3/CD36/CDC34/CALCR/ADCYAP1R1/ADRA1B/ADRA2A/ADRB1/ADORA2B/ADCY8/ADCY3/ADCYAP1/ADORA2A/ADCY2" 28 +"GO:0002673" "GO:0002673" "regulation of acute inflammatory response" "32/743" "150/17381" 3.11713179394204e-14 2.27199394840142e-12 1.36331190394797e-12 "CFB/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/BTK/CD81/C5/C1R/A2M/CD19/C1QB/C8B/C7/C4BPB/C3/C9/C5AR1/ADCYAP1/C4B/C1QC/C4A/CD59/ADAM8/APCS/C1QBP/SERPING1/ADORA1" 32 +"GO:0070482" "GO:0070482" "response to oxygen levels" "52/743" "371/17381" 3.58135468812013e-14 2.57409868208634e-12 1.54459010671848e-12 "BNIP3L/BIRC2/BMP2/CASP1/CDKN1B/ALAS2/ADM/ACVRL1/AHCY/CDK4/FAS/CCNB1/AKT1/BACH1/AGER/CA9/ARNT/BAD/CD34/CASR/ATP7A/ANG/ALAD/ASCL2/ATP6V1A/CAT/ADA/ATP6AP1/BMP7/CDKN1A/CAV1/BCL2/AQP3/ABAT/CD38/ATP1B1/CBFA2T3/ATM/AQP1/ZFP36L1/ANGPT2/CAPN2/ACTN4/ALDH3A1/CASP3/CCNA2/APAF1/ADAM8/ADSL/BNIP3/CBL/ADORA1" 52 +"GO:0030449" "GO:0030449" "regulation of complement activation" "27/743" "107/17381" 4.1912453626324e-14 2.97119106186612e-12 1.78286572743556e-12 "CFB/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/CD81/C5/C1R/A2M/CD19/C1QB/C8B/C7/C4BPB/C3/C9/C5AR1/C4B/C1QC/C4A/CD59/C1QBP/SERPING1" 27 +"GO:0002526" "GO:0002526" "acute inflammatory response" "38/743" "212/17381" 4.5951625947625e-14 3.20382190292116e-12 1.92245606175793e-12 "CFB/C4BPA/C2/C8A/C8G/C1QA/CD6/C6/C1S/C3AR1/BTK/CD81/SERPINA3/SERPINC1/C5/C1R/A2M/CD19/C1QB/C8B/C7/C4BPB/C3/C9/APOA2/ACVR1/C5AR1/ADCYAP1/C4B/C1QC/C4A/CD59/AHSG/ADAM8/APCS/C1QBP/SERPING1/ADORA1" 38 +"GO:0042310" "GO:0042310" "vasoconstriction" "23/743" "76/17381" 4.6432201491611e-14 3.20382190292116e-12 1.92245606175793e-12 "BDKRB2/BBS2/ADM/AVPR1A/AGT/AVPR1B/AKT1/ACTA2/ASIC2/ADRA1D/ADRA1A/ADRA2B/ADRA2C/CASR/BMPR2/AGTR1/ADRA1B/ADRA2A/ATP1A2/CAV1/CD38/AVPR2/AVP" 23 +"GO:0000079" "GO:0000079" "regulation of cyclin-dependent protein serine/threonine kinase activity" "24/743" "84/17381" 5.44963255515346e-14 3.66257772375574e-12 2.19773288280283e-12 "CCNC/CDKN1B/CDC25C/CCNH/CDKN2D/CCNB1/AKT1/CCND2/CDK7/APC/CCNT1/CCNG1/CDC6/CDKN2B/CDKN1A/CCNT2/BLM/CCND3/CASP3/CDKN2A/CDC25A/CDKN3/CCND1/CDKN2C" 24 +"GO:0097756" "GO:0097756" "negative regulation of blood vessel diameter" "24/743" "84/17381" 5.44963255515346e-14 3.66257772375574e-12 2.19773288280283e-12 "BDKRB2/BBS2/ADM/AVPR1A/AGT/AVPR1B/AKT1/ACTA2/ASIC2/ADRA1D/ADRA1A/ADRA2B/ADRA2C/CASR/BMPR2/AGTR1/ADRA1B/ADRA2A/ATP1A2/CAV1/CD38/AVPR2/AVP/ADORA1" 24 +"GO:0030100" "GO:0030100" "regulation of endocytosis" "38/743" "214/17381" 6.27041461377815e-14 4.16017892644897e-12 2.49631890831924e-12 "APOC2/C4BPA/C2/ANXA2/APOC3/AXL/ABL2/SCARB1/CD47/AZU1/BIN1/APOE/ARRB1/ARF1/ABR/BCR/CAV3/CD36/ALOX15/ARRB2/CAV1/C4BPB/C3/BICD1/CD63/CD14/CALR/ARF6/ACTN4/C4B/APOC1/C4A/CDH13/AHSG/ABL1/CBL/B2M/ANGPT1" 38 +"GO:0051604" "GO:0051604" "protein maturation" "51/743" "364/17381" 6.46145939642499e-14 4.23266485778473e-12 2.53981415315839e-12 "CFB/BIRC2/CASP1/C4BPA/C2/C8A/C8G/C1QA/AGA/C6/AGT/SERPINH1/C1S/ASPH/C3AR1/CD81/BAD/BGLAP/CAST/CASP2/C5/C1R/A2M/CD19/C1QB/C8B/C7/XIAP/CASP8/C4BPB/C3/APOH/C9/CALR/BIRC3/PARP1/C5AR1/AEBP1/CAPN2/C4B/CASP3/C1QC/BIRC5/C4A/CD59/ADAM8/ADAM10/AANAT/C1QBP/SERPING1/BAK1" 51 +"GO:0030810" "GO:0030810" "positive regulation of nucleotide biosynthetic process" "27/743" "109/17381" 6.84925506987577e-14 4.37591296130952e-12 2.62577029969247e-12 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 27 +"GO:1900373" "GO:1900373" "positive regulation of purine nucleotide biosynthetic process" "27/743" "109/17381" 6.84925506987577e-14 4.37591296130952e-12 2.62577029969247e-12 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 27 +"GO:0051924" "GO:0051924" "regulation of calcium ion transport" "39/743" "226/17381" 7.64617844855024e-14 4.82548456966433e-12 2.89553612621607e-12 "CASQ1/CALM1/APLNR/CACNB4/CACNA1C/BDKRB1/CD4/CAMK2B/CALM3/AGT/TSPO/CAMK2D/CAV3/CALM2/CASR/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ADRA2A/ATP1A2/CAMK2G/ARRB2/CAV1/BCL2/CACNA1B/CACNA1D/ATP1B1/CACNB1/CASQ2/ADORA2A/ANK2/CACNB2/CACNB3/CAMK2A/ABL1/BAK1" 39 +"GO:0070613" "GO:0070613" "regulation of protein processing" "33/743" "166/17381" 1.04641897776455e-13 6.52435928907416e-12 3.91494734864353e-12 "CFB/BIRC2/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/CD81/CAST/C5/C1R/A2M/CD19/C1QB/C8B/C7/XIAP/C4BPB/C3/C9/BIRC3/C5AR1/C4B/C1QC/BIRC5/C4A/CD59/ADAM8/C1QBP/SERPING1" 33 +"GO:0019933" "GO:0019933" "cAMP-mediated signaling" "26/743" "103/17381" 1.23218755738115e-13 7.59115548743743e-12 4.55507931613332e-12 "APLNR/ADM/ADRB2/ADCY1/CALCA/ADCY6/ADRA1D/ADRA1A/ADCY5/ADCY9/ADCY7/ADRA2B/ADRA2C/ADRB3/CDC34/CALCR/ADCYAP1R1/ADRA1B/ADRA2A/ADRB1/ADORA2B/ADCY8/ADCY3/ADCYAP1/ADORA2A/ADCY2" 26 +"GO:0009167" "GO:0009167" "purine ribonucleoside monophosphate metabolic process" "46/743" "310/17381" 1.38426209497034e-13 8.32370636366892e-12 4.99464709337875e-12 "ATP5F1/ALDOC/ALDOA/BID/CDK1/ADK/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/AMPD1/ATP5O/ATP7A/ATP6V1B1/ATIC/ACTN3/ATP6V1A/ATP5G3/ADA/BPGM/ATP1A2/ATP5D/ATP5J/APRT/AK1/ALDOB/ATP1B1/CBFA2T3/AMPD2/AK4/PARP1/ADCYAP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 46 +"GO:0009161" "GO:0009161" "ribonucleoside monophosphate metabolic process" "47/743" "322/17381" 1.39080230013933e-13 8.32370636366892e-12 4.99464709337875e-12 "ATP5F1/ALDOC/ALDOA/CAD/BID/CDK1/ADK/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/AMPD1/ATP5O/ATP7A/ATP6V1B1/ATIC/ACTN3/ATP6V1A/ATP5G3/ADA/BPGM/ATP1A2/ATP5D/ATP5J/APRT/AK1/ALDOB/ATP1B1/CBFA2T3/AMPD2/AK4/PARP1/ADCYAP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 47 +"GO:0030801" "GO:0030801" "positive regulation of cyclic nucleotide metabolic process" "27/743" "112/17381" 1.39934773650086e-13 8.32370636366892e-12 4.99464709337875e-12 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/ADCYAP1R1/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 27 +"GO:1903317" "GO:1903317" "regulation of protein maturation" "33/743" "168/17381" 1.49630894408495e-13 8.79931680186319e-12 5.28003754192655e-12 "CFB/BIRC2/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/CD81/CAST/C5/C1R/A2M/CD19/C1QB/C8B/C7/XIAP/C4BPB/C3/C9/BIRC3/C5AR1/C4B/C1QC/BIRC5/C4A/CD59/ADAM8/C1QBP/SERPING1" 33 +"GO:0009126" "GO:0009126" "purine nucleoside monophosphate metabolic process" "46/743" "311/17381" 1.56006999521626e-13 9.07119351151028e-12 5.44317739312592e-12 "ATP5F1/ALDOC/ALDOA/BID/CDK1/ADK/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/AMPD1/ATP5O/ATP7A/ATP6V1B1/ATIC/ACTN3/ATP6V1A/ATP5G3/ADA/BPGM/ATP1A2/ATP5D/ATP5J/APRT/AK1/ALDOB/ATP1B1/CBFA2T3/AMPD2/AK4/PARP1/ADCYAP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 46 +"GO:0034330" "GO:0034330" "cell junction organization" "42/743" "265/17381" 1.69497921458809e-13 9.74613048388154e-12 5.84817389828641e-12 "ACVRL1/ACTN1/AGT/CDH7/CDH3/RUNX1/ACTN2/CDH2/APC/CD9/ADD1/CDH5/CDH8/ANG/CDC42/ARL2/ACTN3/ACTB/CDH10/ACTG1/RHOC/CD151/CDH11/CAV1/BCL2/CAPZA1/CDH18/RHOA/CBFB/ARHGAP6/CDH12/ACTN4/CDH1/APOD/CDH9/ANK2/CDH15/CDH13/CDH17/CDH4/ABL1/CDH6" 42 +"GO:0034332" "GO:0034332" "adherens junction organization" "28/743" "123/17381" 2.30413545731423e-13 1.31031879028584e-11 7.86257906197454e-12 "ACVRL1/ACTN1/CDH7/CDH3/ACTN2/CDH2/ADD1/CDH5/CDH8/ANG/CDC42/ACTN3/CDH10/CDH11/BCL2/CDH18/RHOA/ARHGAP6/CDH12/CDH1/APOD/CDH9/CDH15/CDH13/CDH17/CDH4/ABL1/CDH6" 28 +"GO:1902600" "GO:1902600" "hydrogen ion transmembrane transport" "26/743" "106/17381" 2.56175473112827e-13 1.44098703625965e-11 8.64665498492951e-12 "ATP6V1C1/ATP5F1/ATP12A/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/ATP6V0A1/ATP5I/ATP4B/ATP5O/ATP6V1B1/ATP6V1A/ATP5G3/ATP1A2/ATP6AP1/ATP4A/ATP5D/ATP5J/ATP6V0C/ATP6V0B/ATP1A4/ATP6V1E1/ATP5G2/ATP5B/ATP5A1" 26 +"GO:0070838" "GO:0070838" "divalent metal ion transport" "57/743" "456/17381" 2.97694771086961e-13 1.65652735524196e-11 9.94000650488438e-12 "ANXA6/CASQ1/CALM1/APLNR/CACNB4/CACNA1C/CACNG1/BDKRB1/CD4/CAMK2B/CALM3/AGT/ATP2B1/ATP2A2/TSPO/ADRA1A/ATP2B4/CAMK2D/CAV3/CALM2/CASR/CACNA1F/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ATP2B3/ADRA2A/ATP1A2/FASLG/CAMK2G/CACNA1S/ARRB2/CAV1/BCL2/ATP2A3/CACNA1B/CACNA1D/ATP2A1/ATP1B1/CACNB1/ASIC1/CASQ2/ADORA2A/ATP2B2/CACNA1E/ANK2/CDK5/CACNB2/CACNA1A/CACNB3/CAMK2A/ABL1/B2M/BAK1" 57 +"GO:0007568" "GO:0007568" "aging" "44/743" "294/17381" 3.51241360569821e-13 1.93369578824343e-11 1.16031580479392e-11 "APP/BCL2A1/ATR/ADM/BRCA2/CDK1/CASP9/CDK6/ARG2/AGT/CALCA/AKT1/BMPR1A/ATP2B1/AGER/TSPO/ADRA1A/BGLAP/AMFR/CASP2/ADRB3/AMH/CANX/CAT/ALOX12/ADA/CDKN1A/BCL2/ABAT/BCL6/ATM/CALR/ARNTL/CDKN1C/ALDH3A1/APOD/CDKN2A/ARG1/APAF1/APEX1/CD86/SERPING1/ABL1/BAK1" 44 +"GO:0043312" "GO:0043312" "neutrophil degranulation" "59/743" "485/17381" 3.65421677760655e-13 1.99058650780146e-11 1.19445312952236e-11 "ALDOC/ALDOA/ANXA2/A1BG/CD68/AGA/BPI/ADGRE5/CD47/AZU1/C3AR1/ATP6V0A1/AMPD3/ASAH1/ABR/SERPINA3/BCR/ACLY/AOC1/CDA/CD36/APEH/ALAD/CAT/RHOG/CAPN1/ANXA3/ACPP/APRT/CAMP/ATP6V0C/ANPEP/ALDH3B1/CD33/C3/RHOA/CD63/CEACAM1/CD14/ARSB/ACAA1/BST1/BST2/C5AR1/AGL/CD53/AP2A2/ARSA/ALOX5/CD59/CD44/ARG1/CD58/APAF1/AHSG/ADAM8/ADAM10/MS4A3/B2M" 59 +"GO:0060191" "GO:0060191" "regulation of lipase activity" "23/743" "83/17381" 3.75926410817221e-13 2.02647830831158e-11 1.21599003498991e-11 "ANXA1/APOC2/ARF4/APOC3/ABL2/AVPR1A/AGT/AVPR1B/ADRA1A/APOA4/ANG/ADCYAP1R1/APOA1/AGTR1/RHOC/ARL1/APOH/BICD1/RHOA/APOA2/C5AR1/APOC1/ABL1" 23 +"GO:0002283" "GO:0002283" "neutrophil activation involved in immune response" "59/743" "486/17381" 3.99478175581734e-13 2.13123665838708e-11 1.27885037218244e-11 "ALDOC/ALDOA/ANXA2/A1BG/CD68/AGA/BPI/ADGRE5/CD47/AZU1/C3AR1/ATP6V0A1/AMPD3/ASAH1/ABR/SERPINA3/BCR/ACLY/AOC1/CDA/CD36/APEH/ALAD/CAT/RHOG/CAPN1/ANXA3/ACPP/APRT/CAMP/ATP6V0C/ANPEP/ALDH3B1/CD33/C3/RHOA/CD63/CEACAM1/CD14/ARSB/ACAA1/BST1/BST2/C5AR1/AGL/CD53/AP2A2/ARSA/ALOX5/CD59/CD44/ARG1/CD58/APAF1/AHSG/ADAM8/ADAM10/MS4A3/B2M" 59 +"GO:0072511" "GO:0072511" "divalent inorganic cation transport" "57/743" "460/17381" 4.30819259444412e-13 2.25200976527761e-11 1.35132037784265e-11 "ANXA6/CASQ1/CALM1/APLNR/CACNB4/CACNA1C/CACNG1/BDKRB1/CD4/CAMK2B/CALM3/AGT/ATP2B1/ATP2A2/TSPO/ADRA1A/ATP2B4/CAMK2D/CAV3/CALM2/CASR/CACNA1F/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ATP2B3/ADRA2A/ATP1A2/FASLG/CAMK2G/CACNA1S/ARRB2/CAV1/BCL2/ATP2A3/CACNA1B/CACNA1D/ATP2A1/ATP1B1/CACNB1/ASIC1/CASQ2/ADORA2A/ATP2B2/CACNA1E/ANK2/CDK5/CACNB2/CACNA1A/CACNB3/CAMK2A/ABL1/B2M/BAK1" 57 +"GO:0090066" "GO:0090066" "regulation of anatomical structure size" "57/743" "460/17381" 4.30819259444412e-13 2.25200976527761e-11 1.35132037784265e-11 "BDKRB2/BBS2/ADM/ADRB2/AVPR1A/CDK4/AGT/AVPR1B/CALCA/AKT1/ACTA2/ASIC2/ADCY6/APOE/ADRA1D/ADRA1A/ARF1/ACTN2/ADRA2B/ANXA7/ADD1/CAV3/ADRA2C/ADRB3/BBS4/ADD2/CAPZB/CASR/ATP7A/BMPR2/BDNF/CAPG/AGTR1/ADRA1B/ALOX12/ADRA2A/ATP1A2/ALOX15/ADRB1/ADORA2B/CAV1/ARHGAP4/CAPZA2/CD38/CAPZA1/RHOA/AGTR2/AQP1/ARF6/ADCYAP1/ADORA2A/CDK5/AVPR2/AVP/CDH4/ABL1/ADORA1" 57 +"GO:0043434" "GO:0043434" "response to peptide hormone" "53/743" "410/17381" 5.52567590608198e-13 2.85953728139743e-11 1.7158677813623e-11 "CDO1/ATP6V1C1/ANXA1/CDKN1B/ADM/CDK4/AKT2/AGT/ADCY1/AKT1/ATP6V1B2/ADCY6/ATP6V0A1/ADCY5/ADCY9/ADCY7/ACTN2/APC/CDC5L/BSG/AGRP/AREG/ATP6V1B1/CDC6/ATP6V1A/AGTR1/CAT/ATP6AP1/BMP7/ATP6V1G2/APRT/CAV1/ATP6V0C/BRAF/ATP6V0B/ATP6V1E1/AGTR2/CEACAM1/CCND3/ADCY8/PARP1/ADCY3/CAV2/ZFP36L1/APOBEC1/CA2/ARG1/CCNA2/AHSG/APEX1/AANAT/ADCY2/CAMK2A" 53 +"GO:0030004" "GO:0030004" "cellular monovalent inorganic cation homeostasis" "26/743" "110/17381" 6.51684779170241e-13 3.3390779526792e-11 2.0036165696219e-11 "ATP6V1C1/AVPR1A/AGT/ATP1B3/ATP6V1B2/ATP6V0A1/ATP1A3/ATP1B2/ATP1A1/ATP6V1B1/ATP6V1A/ATP1A2/FASLG/ATP6V1G2/C7/ATP6V0C/BCL2/ATP6V0B/ATP1A4/ATP1B1/ATP6V1E1/AGTR2/CA2/CA7/AVP/ATP5B" 26 +"GO:0002521" "GO:0002521" "leukocyte differentiation" "58/743" "479/17381" 7.12135265965069e-13 3.61303921702866e-11 2.16800725964598e-11 "ANXA1/APP/ANXA2/AXL/CD4/CDK6/FAS/CD74/CD79A/RHOH/AGER/RUNX1/RUNX2/CD80/BTK/BAD/BGLAP/CD3E/CD27/AIRE/ATP7A/CD3D/PRDM1/CDC42/BAX/ADA/CD8A/ATP6AP1/ZFP36L2/CD79B/CASP8/BCL2/TNFSF8/BRAF/BCL6/CBFB/CBFA2T3/BCL3/CD2/BMX/CEACAM1/ATM/PARP1/ZFP36L1/CAMK4/C1QC/CA2/CD28/ADAM8/CD1D/CD40LG/APCS/BMP4/CDH17/CD86/ABL1/B2M/BAK1" 58 +"GO:0009123" "GO:0009123" "nucleoside monophosphate metabolic process" "47/743" "337/17381" 7.59598822499748e-13 3.81643097712252e-11 2.29005265853271e-11 "ATP5F1/ALDOC/ALDOA/CAD/BID/CDK1/ADK/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/AMPD1/ATP5O/ATP7A/ATP6V1B1/ATIC/ACTN3/ATP6V1A/ATP5G3/ADA/BPGM/ATP1A2/ATP5D/ATP5J/APRT/AK1/ALDOB/ATP1B1/CBFA2T3/AMPD2/AK4/PARP1/ADCYAP1/ATP5G2/AK2/ATP5B/ATP5A1/ADSL/ADSS" 47 +"GO:0030817" "GO:0030817" "regulation of cAMP biosynthetic process" "28/743" "129/17381" 8.10623162420064e-13 4.0336296783883e-11 2.42038292422995e-11 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 28 +"GO:0002697" "GO:0002697" "regulation of immune effector process" "52/743" "402/17381" 8.98991748377364e-13 4.43074504557415e-11 2.65867233855962e-11 "CFB/ANXA1/BIRC2/C4BPA/C2/C8A/C8G/C1QA/C6/CD74/AGER/C1S/C3AR1/CD80/BTK/CD81/ABR/BCR/AP1G1/C5/CD36/C1R/A2M/APOA1/CD19/C1QB/C8B/C7/ADORA2B/ARRB2/CD40/BCL6/C4BPB/C3/C9/APOA2/CEACAM1/BST2/BIRC3/C5AR1/C4B/C1QC/C4A/CD59/ARG1/CD28/CD40LG/C1QBP/CD86/SERPING1/B2M/ANGPT1" 52 +"GO:0042119" "GO:0042119" "neutrophil activation" "59/743" "496/17381" 9.58866997544623e-13 4.68126104933342e-11 2.80899467999666e-11 "ALDOC/ALDOA/ANXA2/A1BG/CD68/AGA/BPI/ADGRE5/CD47/AZU1/C3AR1/ATP6V0A1/AMPD3/ASAH1/ABR/SERPINA3/BCR/ACLY/AOC1/CDA/CD36/APEH/ALAD/CAT/RHOG/CAPN1/ANXA3/ACPP/APRT/CAMP/ATP6V0C/ANPEP/ALDH3B1/CD33/C3/RHOA/CD63/CEACAM1/CD14/ARSB/ACAA1/BST1/BST2/C5AR1/AGL/CD53/AP2A2/ARSA/ALOX5/CD59/CD44/ARG1/CD58/APAF1/AHSG/ADAM8/ADAM10/MS4A3/B2M" 59 +"GO:0045216" "GO:0045216" "cell-cell junction organization" "38/743" "233/17381" 9.9419574824355e-13 4.78690767729338e-11 2.87238802909036e-11 "ACVRL1/ACTN1/AGT/CDH7/CDH3/RUNX1/ACTN2/CDH2/APC/CD9/ADD1/CDH5/CDH8/ANG/CDC42/ARL2/ACTN3/CDH10/RHOC/CDH11/CAV1/BCL2/CDH18/RHOA/CBFB/ARHGAP6/CDH12/ACTN4/CDH1/APOD/CDH9/ANK2/CDH15/CDH13/CDH17/CDH4/ABL1/CDH6" 38 +"GO:0006936" "GO:0006936" "muscle contraction" "48/743" "352/17381" 9.99006819609053e-13 4.78690767729338e-11 2.87238802909036e-11 "BDKRB2/ANXA6/BBS2/ALDOA/CASQ1/CALM1/ADRB2/CACNA1C/CACNG1/ARG2/CALM3/AGT/CALCA/ACTA2/ATP2A2/ASPH/ACTA1/ADRA1D/ADRA1A/ATP1A3/ACTN2/ATP1A1/ADRA2B/CAMK2D/CAV3/ADRA2C/CALM2/CACNA2D1/CALD1/ACTN3/ADRA1B/ADA/ADRA2A/ATP1A2/CACNA1S/ADORA2B/CAV1/ABAT/ACTG2/CACNA1D/ACTC1/ATP2A1/ATP1B1/CASQ2/GRK2/ANK2/CACNB2/ADORA1" 48 +"GO:0006069" "GO:0006069" "ethanol oxidation" "10/743" "12/17381" 1.17333589290802e-12 5.57065435394404e-11 3.34267588998422e-11 "ALDH1B1/ADH1B/ADH1A/ADH7/ADH5/ADH6/ADH4/ALDH1A1/ALDH2/ADH1C" 10 +"GO:0002446" "GO:0002446" "neutrophil mediated immunity" "59/743" "499/17381" 1.24023003908089e-12 5.83471859294872e-11 3.50112786152021e-11 "ALDOC/ALDOA/ANXA2/A1BG/CD68/AGA/BPI/ADGRE5/CD47/AZU1/C3AR1/ATP6V0A1/AMPD3/ASAH1/ABR/SERPINA3/BCR/ACLY/AOC1/CDA/CD36/APEH/ALAD/CAT/RHOG/CAPN1/ANXA3/ACPP/APRT/CAMP/ATP6V0C/ANPEP/ALDH3B1/CD33/C3/RHOA/CD63/CEACAM1/CD14/ARSB/ACAA1/BST1/BST2/C5AR1/AGL/CD53/AP2A2/ARSA/ALOX5/CD59/CD44/ARG1/CD58/APAF1/AHSG/ADAM8/ADAM10/MS4A3/B2M" 59 +"GO:0042776" "GO:0042776" "mitochondrial ATP synthesis coupled proton transport" "12/743" "19/17381" 1.30550247739527e-12 6.0864642527212e-11 3.65218805909535e-11 "ATP5F1/ATP5C1/ATP5G1/ATP5E/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/ATP5G2/ATP5B/ATP5A1" 12 +"GO:0006171" "GO:0006171" "cAMP biosynthetic process" "28/743" "132/17381" 1.47657275444744e-12 6.82255714666564e-11 4.09388122708642e-11 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 28 +"GO:0003012" "GO:0003012" "muscle system process" "55/743" "448/17381" 1.64808669875163e-12 7.54765368676078e-11 4.52897602358389e-11 "BDKRB2/ANXA6/BBS2/ALDOA/CASQ1/CALM1/AIF1/ADRB2/CACNA1C/CACNG1/CAMK2B/ARG2/CALM3/AGT/CALCA/ACTA2/ATP2A2/ASPH/ACTA1/ADRA1D/ADRA1A/ATP1A3/ACTN2/ATP2B4/ATP1A1/ADRA2B/CAMK2D/CAV3/ADRA2C/CALM2/CACNA2D1/CDK9/CALD1/ACTN3/ADRA1B/ADA/ADRA2A/ATP1A2/CAMK2G/CACNA1S/ADORA2B/CAV1/ABAT/ACTG2/CACNA1D/ACTC1/ATP2A1/ATP1B1/AGTR2/PARP1/CASQ2/GRK2/ANK2/CACNB2/ADORA1" 55 +"GO:0052652" "GO:0052652" "cyclic purine nucleotide metabolic process" "31/743" "163/17381" 2.02122793247053e-12 9.1753110092412e-11 5.50565318632322e-11 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/AMPD2/AQP1/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 31 +"GO:0019216" "GO:0019216" "regulation of lipid metabolic process" "48/743" "360/17381" 2.29788832198338e-12 1.03404974489252e-10 6.20482430192308e-11 "ANXA1/BMP2/APOC2/APOC3/AVPR1A/CDK4/SCARB1/ACOX1/ALAS1/AKT2/AGT/AKT1/TSPO/APOE/CD81/ARF1/APOA4/ACACA/ATP1A1/SERPINA3/ABCD2/ACADM/ABCA1/BBS4/AADAC/CD36/CDC42/APOA1/AGTR1/ADRA2A/CAV1/ACADVL/CCKBR/ACADL/C3/ACACB/APOA2/CEACAM1/BMP6/APOBEC1/BMP5/APOD/PLIN2/BRCA1/AVP/APOC1/APOB/ADORA1" 48 +"GO:0002920" "GO:0002920" "regulation of humoral immune response" "27/743" "125/17381" 2.35275588412768e-12 1.04961307761731e-10 6.29821221250150e-11 "CFB/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/CD81/C5/C1R/A2M/CD19/C1QB/C8B/C7/C4BPB/C3/C9/C5AR1/C4B/C1QC/C4A/CD59/C1QBP/SERPING1" 27 +"GO:0009190" "GO:0009190" "cyclic nucleotide biosynthetic process" "31/743" "164/17381" 2.39316154766893e-12 1.05851376146895e-10 6.35162084176639e-11 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/AMPD2/AQP1/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 31 +"GO:0008217" "GO:0008217" "regulation of blood pressure" "32/743" "175/17381" 2.70150994996718e-12 1.18477237212544e-10 7.10923671043994e-11 "ADM/ADRB2/ACVRL1/BDKRB1/AVPR1A/AGT/AVPR1B/CALCA/ACTA2/ASIC2/ADRA1D/ADRA1A/AR/CD34/ATP1A1/ADRA2B/ADRB3/BBS4/BMPR2/AGTR1/ADRA1B/ATP1A2/ADH5/ADRB1/ABAT/ANPEP/CACNA1B/AGTR2/BRS3/AVPR2/AVP/ADORA1" 32 +"GO:0036293" "GO:0036293" "response to decreased oxygen levels" "47/743" "349/17381" 2.73142614256788e-12 1.1878260746041e-10 7.1275604781736e-11 "BNIP3L/BIRC2/BMP2/CASP1/CDKN1B/ALAS2/ADM/ACVRL1/AHCY/CCNB1/AKT1/BACH1/AGER/CA9/ARNT/BAD/CD34/CASR/ATP7A/ANG/ALAD/ASCL2/CAT/ADA/BMP7/CAV1/BCL2/AQP3/ABAT/CD38/ATP1B1/CBFA2T3/ATM/AQP1/ZFP36L1/ANGPT2/CAPN2/ACTN4/ALDH3A1/CASP3/CCNA2/APAF1/ADAM8/ADSL/BNIP3/CBL/ADORA1" 47 +"GO:0031281" "GO:0031281" "positive regulation of cyclase activity" "19/743" "60/17381" 3.03773174442971e-12 1.29919518821684e-10 7.7958317930123e-11 "ADRB2/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/ADRB3/CALCR/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2" 19 +"GO:0051349" "GO:0051349" "positive regulation of lyase activity" "19/743" "60/17381" 3.03773174442971e-12 1.29919518821684e-10 7.7958317930123e-11 "ADRB2/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/ADRB3/CALCR/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2" 19 +"GO:0003091" "GO:0003091" "renal water homeostasis" "15/743" "35/17381" 3.70073334577186e-12 1.5697782839647e-10 9.41946796378514e-11 "AQP2/ADCY1/ADCY6/ADCY5/ADCY9/ADCY7/AQP4/AQP3/AKR1B1/AQP1/ADCY8/ADCY3/AVPR2/AVP/ADCY2" 15 +"GO:0030098" "GO:0030098" "lymphocyte differentiation" "45/743" "328/17381" 4.21581877288085e-12 1.77372863005353e-10 1.06432737526731e-10 "ANXA1/AXL/CD4/CDK6/FAS/CD74/CD79A/RHOH/RUNX1/RUNX2/CD80/BTK/BAD/CD3E/CD27/AIRE/ATP7A/CD3D/PRDM1/BAX/ADA/CD8A/ZFP36L2/CD79B/BCL2/TNFSF8/BRAF/BCL6/CBFB/BCL3/CD2/BMX/ATM/ZFP36L1/CAMK4/CD28/ADAM8/CD1D/CD40LG/BMP4/CDH17/CD86/ABL1/B2M/BAK1" 45 +"GO:0001666" "GO:0001666" "response to hypoxia" "46/743" "341/17381" 4.41990543676395e-12 1.84459763187528e-10 1.10685238017433e-10 "BNIP3L/BIRC2/BMP2/CASP1/CDKN1B/ALAS2/ADM/ACVRL1/AHCY/CCNB1/AKT1/BACH1/AGER/CA9/ARNT/BAD/CD34/CASR/ATP7A/ANG/ALAD/ASCL2/CAT/ADA/BMP7/CAV1/BCL2/AQP3/ABAT/CD38/ATP1B1/CBFA2T3/ATM/AQP1/ZFP36L1/ANGPT2/CAPN2/ACTN4/ALDH3A1/CASP3/CCNA2/APAF1/ADAM8/ADSL/BNIP3/ADORA1" 46 +"GO:0032846" "GO:0032846" "positive regulation of homeostatic process" "36/743" "222/17381" 4.71196070172981e-12 1.95075173051614e-10 1.17055023748235e-10 "ANXA1/CASQ1/CALM1/APLNR/ATR/ATRX/BDKRB1/AVPR1A/CD4/CALM3/AGT/ACVR1B/ARRB1/ARNT/BAD/CALM2/CAPN3/CALCR/BAX/ADCYAP1R1/CD19/ATP6AP1/CCT6A/CAV1/ABAT/AGTR2/ATM/CASQ2/ADORA2A/ACVR2A/CA2/CA7/AVP/ADAM8/ABL1/BAK1" 36 +"GO:0006140" "GO:0006140" "regulation of nucleotide metabolic process" "40/743" "269/17381" 5.22694277026633e-12 2.14678006635939e-10 1.28817720737558e-10 "CALM1/ADM/ADRB2/CDK1/ENTPD5/CALM3/ADCY1/CALCA/CCNB1/ADCY6/TSPO/APOE/ARNT/ADCY5/ADCY9/ADCY7/ADORA3/CDA/CALM2/ADRB3/ABCA1/ATP7A/CALCR/APLP1/ACTN3/ADCYAP1R1/BPGM/ADRA2A/ADRB1/ADORA2B/ACR/CBFA2T3/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 40 +"GO:0071825" "GO:0071825" "protein-lipid complex subunit organization" "17/743" "48/17381" 5.431318756567e-12 2.2131554775775e-10 1.3280058294134e-10 "APOC2/APOC3/APOC4/SCARB1/AGT/ALB/BIN1/APOE/ARF1/APOA4/ABCA1/APOA1/AGTR1/BMP1/APOA2/APOC1/APOB" 17 +"GO:1900371" "GO:1900371" "regulation of purine nucleotide biosynthetic process" "30/743" "159/17381" 5.68893414045277e-12 2.30001829506586e-10 1.38012793703418e-10 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 30 +"GO:0030802" "GO:0030802" "regulation of cyclic nucleotide biosynthetic process" "29/743" "149/17381" 5.7448254947815e-12 2.3046102275577e-10 1.38288333003716e-10 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 29 +"GO:0030808" "GO:0030808" "regulation of nucleotide biosynthetic process" "30/743" "160/17381" 6.72317868237508e-12 2.67634228317623e-10 1.6059414666402e-10 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 30 +"GO:0006067" "GO:0006067" "ethanol metabolic process" "12/743" "21/17381" 7.03603671175515e-12 2.76633705686442e-10 1.65994290724638e-10 "ALDH1B1/ADH1B/ADH1A/ADH7/ADH5/ADH6/ADH4/ALDH3B1/ALDH1A1/ALDH3B2/ALDH2/ADH1C" 12 +"GO:0030217" "GO:0030217" "T cell differentiation" "36/743" "225/17381" 7.05616408707445e-12 2.76633705686442e-10 1.65994290724638e-10 "ANXA1/CD4/CDK6/FAS/CD74/RHOH/RUNX1/RUNX2/CD80/BAD/CD3E/CD27/AIRE/ATP7A/CD3D/PRDM1/ADA/CD8A/ZFP36L2/BCL2/TNFSF8/BRAF/BCL6/CBFB/BCL3/CD2/BMX/ZFP36L1/CAMK4/CD28/ADAM8/CD1D/BMP4/CD86/ABL1/B2M" 36 +"GO:0090257" "GO:0090257" "regulation of muscle system process" "37/743" "237/17381" 7.62792154523684e-12 2.96800706741358e-10 1.78095516885229e-10 "ANXA6/CASQ1/CALM1/AIF1/ADRB2/CACNA1C/CAMK2B/CALM3/AGT/CALCA/ATP2A2/ADRA1D/ADRA1A/ATP2B4/ATP1A1/ADRA2B/CAMK2D/CAV3/ADRA2C/CALM2/CDK9/ACTN3/ADRA1B/ADA/ADRA2A/ATP1A2/CAMK2G/ADORA2B/CAV1/ABAT/ATP2A1/ATP1B1/PARP1/CASQ2/GRK2/ANK2/ADORA1" 37 +"GO:0031667" "GO:0031667" "response to nutrient levels" "52/743" "426/17381" 8.50694113604702e-12 3.28532987903308e-10 1.9713649922497e-10 "ALPL/BBS2/C2/ADM/ADRB2/AHCY/CD4/FAS/CDKN2D/ACAT1/AKT1/BCHE/ALB/ATP2B1/TSPO/APOE/BGLAP/CD3E/SERPINC1/AOC1/CCKAR/ASCL1/ADRB3/ABCA1/BBS4/CASR/BMPR2/ALAD/APOA1/CAT/ADA/BMP7/ADRB1/CDKN2B/CDKN1A/BCL2/AQP3/ATF3/CD40/CCK/ACACB/ARSB/AGL/ADCYAP1/ALDH3A1/ASNS/ARG1/APAF1/ADSL/CCND1/ATF4/CBL" 52 +"GO:0015985" "GO:0015985" "energy coupled proton transport, down electrochemical gradient" "13/743" "26/17381" 8.92260813621168e-12 3.39518361065408e-10 2.03728281747867e-10 "ATP5F1/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/ATP5G2/ATP5B/ATP5A1" 13 +"GO:0015986" "GO:0015986" "ATP synthesis coupled proton transport" "13/743" "26/17381" 8.92260813621168e-12 3.39518361065408e-10 2.03728281747867e-10 "ATP5F1/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/ATP5G2/ATP5B/ATP5A1" 13 +"GO:0006937" "GO:0006937" "regulation of muscle contraction" "30/743" "163/17381" 1.10029291757894e-11 4.15621594778908e-10 2.49394091959884e-10 "ANXA6/CASQ1/CALM1/ADRB2/CACNA1C/CALM3/CALCA/ATP2A2/ADRA1D/ADRA1A/ATP1A1/ADRA2B/CAMK2D/CAV3/ADRA2C/CALM2/ACTN3/ADRA1B/ADA/ADRA2A/ATP1A2/ADORA2B/CAV1/ABAT/ATP2A1/ATP1B1/CASQ2/GRK2/ANK2/ADORA1" 30 +"GO:0015992" "GO:0015992" "proton transport" "29/743" "154/17381" 1.35167494504026e-11 5.06878104390097e-10 3.0415263828137e-10 "ATP6V1C1/ATP5F1/ATP12A/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/ATP6V0A1/ATP5I/ATP4B/ATP5O/ATP7A/ATP6V1B1/ATP6V1A/ATP5G3/ATP1A2/ATP6AP1/ATP4A/ATP5D/ATP5J/ATP6V1G2/ATP6V0C/ATP6V0B/ATP1A4/ATP6V1E1/ACTN4/ATP5G2/ATP5B/ATP5A1" 29 +"GO:1901654" "GO:1901654" "response to ketone" "32/743" "186/17381" 1.47016464056014e-11 5.47345468697749e-10 3.28435114702946e-10 "AVPR1A/CDK4/CASP9/KLF9/ADCY1/AKT1/ATP2B1/CA9/ADCY6/TSPO/ADCY5/BAD/AR/BGLAP/ACACA/CDC5L/CDKN1A/CAV1/CD38/AKR1B1/AGTR2/CALR/AQP1/PARP1/ADCY3/AVP/ARG1/AANAT/BCL2L1/ADCY2/CCND1/CBL" 32 +"GO:0071375" "GO:0071375" "cellular response to peptide hormone stimulus" "42/743" "303/17381" 1.58652109911602e-11 5.86446191994672e-10 3.51897537021975e-10 "ATP6V1C1/CDK4/AKT2/AGT/ADCY1/AKT1/ATP6V1B2/ADCY6/ATP6V0A1/ADCY5/ADCY9/ADCY7/ACTN2/APC/CDC5L/ATP6V1B1/CDC6/ATP6V1A/AGTR1/ATP6AP1/ATP6V1G2/APRT/CAV1/ATP6V0C/ATP6V0B/ATP6V1E1/AGTR2/CEACAM1/CCND3/ADCY8/PARP1/ADCY3/CAV2/ZFP36L1/APOBEC1/CA2/ARG1/CCNA2/AHSG/APEX1/ADCY2/CAMK2A" 42 +"GO:0071880" "GO:0071880" "adenylate cyclase-activating adrenergic receptor signaling pathway" "10/743" "14/17381" 1.64574022766897e-11 6.04021679304036e-10 3.6244372315218e-10 "ADRB2/ADRA1D/ADRA1A/ADCY9/ADRA2B/ADRA2C/ADRB3/ADRA1B/ADRA2A/ADRB1" 10 +"GO:0051928" "GO:0051928" "positive regulation of calcium ion transport" "24/743" "107/17381" 1.67477170388768e-11 6.103481385647e-10 3.66239920420212e-10 "CASQ1/CALM1/APLNR/BDKRB1/CD4/CALM3/TSPO/CALM2/CASR/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ARRB2/CAV1/CACNA1D/ATP1B1/ANK2/CACNB2/CAMK2A/ABL1/BAK1" 24 +"GO:0006818" "GO:0006818" "hydrogen transport" "29/743" "156/17381" 1.88320219618676e-11 6.81508487081573e-10 4.08939748159805e-10 "ATP6V1C1/ATP5F1/ATP12A/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/ATP6V0A1/ATP5I/ATP4B/ATP5O/ATP7A/ATP6V1B1/ATP6V1A/ATP5G3/ATP1A2/ATP6AP1/ATP4A/ATP5D/ATP5J/ATP6V1G2/ATP6V0C/ATP6V0B/ATP1A4/ATP6V1E1/ACTN4/ATP5G2/ATP5B/ATP5A1" 29 +"GO:0030814" "GO:0030814" "regulation of cAMP metabolic process" "28/743" "146/17381" 1.93253041484183e-11 6.94503117833783e-10 4.16737187411068e-10 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 28 +"GO:0006898" "GO:0006898" "receptor-mediated endocytosis" "45/743" "343/17381" 1.98433492756368e-11 7.08202293113246e-10 4.24957389206016e-10 "APOC2/ANXA2/AP2B1/ADM/APOC3/CD6/ADRB2/SCARB1/ALB/AGER/APOE/ARRB1/CD81/ARF1/CD9/CAV3/ASGR2/CD36/CALCR/CANX/APOA1/ACHE/ARRB2/CAV1/AP2A1/CD5L/BICD1/CD63/CEACAM1/CD14/CALR/ARF6/GRK3/AMBP/CAV2/GRK2/CDK5/AP2A2/APOC1/CD5/APOB/CBL/ASGR1/B2M/ANGPT1" 45 +"GO:0071827" "GO:0071827" "plasma lipoprotein particle organization" "16/743" "45/17381" 2.14790977313659e-11 7.61331032601497e-10 4.56837334589253e-10 "APOC2/APOC3/APOC4/SCARB1/AGT/ALB/APOE/ARF1/APOA4/ABCA1/APOA1/AGTR1/BMP1/APOA2/APOC1/APOB" 16 +"GO:0071241" "GO:0071241" "cellular response to inorganic substance" "31/743" "178/17381" 2.2137776872985e-11 7.79340104202023e-10 4.67643693342683e-10 "CDKN1B/ATRX/AQP2/FAS/ADCY1/CCNB1/AKT1/TSPO/BAD/AOC1/ADD1/CAMK2D/ATP7A/CAPN3/ALAD/CDK2/ALOX15/BRAF/ANK3/BLM/CALR/AQP1/PARP1/BMP6/CDH1/ALOX5AP/CCNA2/BNIP3/ATF4/CD86/B2M" 31 +"GO:0097305" "GO:0097305" "response to alcohol" "32/743" "190/17381" 2.63040019452302e-11 9.19751419368693e-10 5.51897622606182e-10 "CDO1/BIRC2/CDK1/AKT1/ADCY6/BAD/ADCY7/BGLAP/ACACA/CD27/ABCA1/ALAD/ADCYAP1R1/CAT/ADH7/ADH6/CA3/CASP8/ABAT/ACTC1/BLM/CD14/ADCYAP1/APOBEC1/CDH1/BRCA1/AVP/AANAT/BCL2L1/CCND1/CBL/BAK1" 32 +"GO:0030104" "GO:0030104" "water homeostasis" "19/743" "67/17381" 2.7056971500802e-11 9.39730386017788e-10 5.63886018561399e-10 "AQP2/ADCY1/ADCY6/ADCY5/ADCY9/ADCY7/ANXA7/AQP4/ALOX12/AQP3/AQP9/AKR1B1/AQP1/ALOX12B/ADCY8/ADCY3/AVPR2/AVP/ADCY2" 19 +"GO:0016053" "GO:0016053" "organic acid biosynthetic process" "43/743" "321/17381" 2.82783162007451e-11 9.69140969131497e-10 5.81533864009746e-10 "CDO1/ANXA1/BCAT1/APOC2/ASL/CAD/KYAT1/APOC3/AHCY/AVPR1A/BAAT/CD74/APOA4/ATP2B4/ACACA/ACLY/ASPA/ATIC/BGN/APOA1/CBS/ALOX12/ALOX15/CBR1/ABAT/ACADVL/BCAT2/AP2A1/ACADL/ALDH1A3/ACACB/ASS1/CEACAM1/ALOX12B/BRCA1/ASNS/AVP/APOC1/ALOX5/ALOX5AP/ALOX15B/BHMT/AGXT" 43 +"GO:0046394" "GO:0046394" "carboxylic acid biosynthetic process" "43/743" "321/17381" 2.82783162007451e-11 9.69140969131497e-10 5.81533864009746e-10 "CDO1/ANXA1/BCAT1/APOC2/ASL/CAD/KYAT1/APOC3/AHCY/AVPR1A/BAAT/CD74/APOA4/ATP2B4/ACACA/ACLY/ASPA/ATIC/BGN/APOA1/CBS/ALOX12/ALOX15/CBR1/ABAT/ACADVL/BCAT2/AP2A1/ACADL/ALDH1A3/ACACB/ASS1/CEACAM1/ALOX12B/BRCA1/ASNS/AVP/APOC1/ALOX5/ALOX5AP/ALOX15B/BHMT/AGXT" 43 +"GO:0045807" "GO:0045807" "positive regulation of endocytosis" "25/743" "119/17381" 2.92509882392573e-11 9.95880685119451e-10 5.97579053364329e-10 "C2/ANXA2/AXL/CD47/AZU1/APOE/ARRB1/ARF1/ABR/BCR/CAV3/CD36/ARRB2/C3/BICD1/CD63/CD14/CALR/ACTN4/C4B/C4A/AHSG/CBL/B2M/ANGPT1" 25 +"GO:0010644" "GO:0010644" "cell communication by electrical coupling" "13/743" "28/17381" 2.96682294562243e-11 1.00348423160759e-09 6.02141567910986e-10 "CALM1/CACNA1C/CALM3/ATP1A3/ATP1B2/ATP1A1/CAMK2D/CALM2/ATP1A2/CAV1/ANK3/ATP1B1/CASQ2" 13 +"GO:0007006" "GO:0007006" "mitochondrial membrane organization" "26/743" "129/17381" 3.16106157429775e-11 1.0622398472072e-09 6.37397925097632e-10 "BNIP3L/ATP5F1/SLC25A6/BID/ATP5C1/ATP5G1/ATP5E/BAD/SLC25A5/BOK/ATP5I/ATP5O/BAX/ATP5G3/ATP5D/ATP5J/CASP8/BCL2/ATP5G2/ATP5B/ATP5A1/BCL2L1/BNIP3/CAMK2A/SLC25A4/BAK1" 26 +"GO:0051249" "GO:0051249" "regulation of lymphocyte activation" "53/743" "455/17381" 3.20850972493617e-11 1.07122824687385e-09 6.4279142197363e-10 "ANXA1/AIF1/CD6/AXL/CD3G/CD4/ARG2/FAS/CD74/AKT1/CD47/AGER/RUNX1/CD80/BTK/CD81/BAD/CD247/CD3E/AP1G1/CD27/CD3D/PRDM1/CDC42/ADA/CDKN1A/ZFP36L2/CAV1/BCL2/BRAF/CD40/BCL6/CD38/CBFB/CD2/CEACAM1/ATM/BST1/ZFP36L1/CAMK4/ADORA2A/AHR/CASP3/CD5/CD59/ARG1/CD28/ADAM8/CD1D/CD40LG/BMP4/CD86/ABL1" 53 +"GO:1900542" "GO:1900542" "regulation of purine nucleotide metabolic process" "38/743" "262/17381" 3.83453781628335e-11 1.27203417944015e-09 7.63285192849925e-10 "CALM1/ADM/ADRB2/CDK1/ENTPD5/CALM3/ADCY1/CALCA/CCNB1/ADCY6/TSPO/APOE/ARNT/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/ATP7A/CALCR/APLP1/ACTN3/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/CBFA2T3/ADCY8/PARP1/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 38 +"GO:0007584" "GO:0007584" "response to nutrient" "30/743" "173/17381" 5.21188336804375e-11 1.7179297088934e-09 1.03084518509749e-09 "ALPL/C2/AHCY/CD4/CDKN2D/BCHE/ATP2B1/TSPO/BGLAP/CD3E/SERPINC1/CCKAR/ASCL1/ABCA1/CASR/ALAD/APOA1/CAT/ADA/BMP7/CDKN2B/AQP3/CD40/ARSB/AGL/ALDH3A1/ARG1/APAF1/ADSL/CCND1" 30 +"GO:0022407" "GO:0022407" "regulation of cell-cell adhesion" "50/743" "425/17381" 8.2755281281115e-11 2.71049734575804e-09 1.62643624103457e-09 "ANXA1/BMP2/AIF1/CD6/CD3G/CD4/ARG2/CD74/AKT1/CD47/AGER/RUNX1/CD80/BAD/CD247/CD9/CD3E/CD27/CD3D/PRDM1/CDC42/APOA1/ALOX12/ADA/BMP7/ALOX15/CAV1/ABAT/BRAF/ANK3/BCL6/CBFB/ASS1/CD2/CEACAM1/CAMK4/ADORA2A/CDH1/CASP3/CD5/CD59/CD44/ARG1/CD28/ADAM8/CD1D/CD40LG/BMP4/CD86/ABL1" 50 +"GO:0071900" "GO:0071900" "regulation of protein serine/threonine kinase activity" "55/743" "495/17381" 8.37446531025941e-11 2.72565144532028e-09 1.63552947138466e-09 "BMP2/CCNC/CDKN1B/CALM1/CDC25C/ADRB2/CDK1/CCNH/CALM3/CD74/CDKN2D/CCNB1/AKT1/AGER/ALK/CCND2/APOE/ARRB1/CDK7/CD81/ATP2B4/ADRA2B/APC/CCNT1/CCNG1/C5/CAV3/CALM2/CDC6/ADRA2A/BMP7/CDKN2B/CDKN1A/ADORA2B/ARAF/CAV1/BRAF/CD40/CCNT2/RHOA/BLM/CCND3/C5AR1/CDKN1C/CASP3/CDKN2A/CDC25A/ADAM8/CDKN3/CD40LG/BMP4/CCND1/CDKN2C/ABL1/ADORA1" 55 +"GO:0052548" "GO:0052548" "regulation of endopeptidase activity" "48/743" "399/17381" 9.21506194232008e-11 2.98049659696915e-09 1.78844952170028e-09 "APP/BIRC2/CASP1/BID/CASP9/FAS/AGT/CDKN2D/AKT1/SERPINH1/ASPH/ARRB1/BAD/BOK/SERPINA3/SERPINC1/CAST/CASP2/C5/CD27/FOXL2/A2M/BAX/ALOX12/FASLG/SERPINA6/ARRB2/XIAP/CASP8/APLP2/C3/CCK/AQP1/BST2/BIRC3/CASP7/AMBP/ADORA2A/C4B/CASP3/BIRC5/AVP/C4A/CD44/APAF1/AHSG/SERPING1/BAK1" 48 +"GO:0097006" "GO:0097006" "regulation of plasma lipoprotein particle levels" "21/743" "89/17381" 1.12377095681242e-10 3.61212093261134e-09 2.1674562422992e-09 "APOC2/ANXA2/AP2B1/APOC3/APOC4/SCARB1/AGT/ALB/APOE/ARF1/APOA4/ABCA1/CD36/APOA1/AGTR1/BMP1/AP2A1/APOA2/AP2A2/APOC1/APOB" 21 +"GO:0044843" "GO:0044843" "cell cycle G1/S phase transition" "39/743" "284/17381" 1.13380505435088e-10 3.62187725695421e-09 2.17331053303126e-09 "ANXA1/BCAT1/CDKN1B/CDC25C/BID/AIF1/CDK1/CCNH/CDK4/CDK6/CDKN2D/CCNB1/AKT1/ACVR1B/BACH1/CCND2/CDK7/ATP2B4/CASP2/CDK3/CDC34/CDC6/BAX/CDK2/CDKN2B/CAMK2G/CDKN1A/CCNE1/BCL2/ACVR1/ATM/CDKN2A/CCNA2/CDC25A/APEX1/CDKN3/CCND1/CAMK2A/CDKN2C" 39 +"GO:0045761" "GO:0045761" "regulation of adenylate cyclase activity" "20/743" "81/17381" 1.29408211762947e-10 4.10851224462115e-09 2.46531627188048e-09 "ADRB2/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/ADRB3/CALCR/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2" 20 +"GO:0051881" "GO:0051881" "regulation of mitochondrial membrane potential" "18/743" "65/17381" 1.39605209589152e-10 4.40522536356014e-09 2.64335923163029e-09 "BNIP3L/CASP1/BID/AKT2/AKT1/TSPO/BAD/BOK/BAX/ALOX12/BCL2/CCK/PARP1/ADORA2A/BCL2L1/BNIP3/ABL1/BAK1" 18 +"GO:0065005" "GO:0065005" "protein-lipid complex assembly" "13/743" "31/17381" 1.45077355653674e-10 4.55015342731976e-09 2.73032343973421e-09 "APOC2/APOC3/APOC4/BIN1/APOE/ARF1/APOA4/ABCA1/APOA1/BMP1/APOA2/APOC1/APOB" 13 +"GO:1904062" "GO:1904062" "regulation of cation transmembrane transport" "39/743" "288/17381" 1.73060496850254e-10 5.39510886265099e-09 3.23733966840995e-09 "APP/CASQ1/CALM1/APLNR/CACNB4/ADRB2/CACNA1C/BDKRB1/CALM3/AGT/ATP1B3/ARF1/ACTN2/ATP2B4/ATP1B2/CAMK2D/CAV3/CALM2/ATP7A/CAPN3/CACNA2D1/CALCR/FXYD2/BAX/CD19/ADRA2A/ATP1A2/CAV1/ANK3/CACNA1D/ATP1B1/CACNB1/CASQ2/ACTN4/ANK2/CACNB2/CACNB3/ABL1/B2M" 39 +"GO:0055078" "GO:0055078" "sodium ion homeostasis" "15/743" "44/17381" 1.82796781955225e-10 5.66451105759453e-09 3.39899468495375e-09 "AVPR1A/AGT/ATP1B3/ATP1A3/ATP1B2/ATP1A1/AGTR1/ATP1A2/C7/ATP1B1/AGTR2/ADORA2A/AVPR2/AVP/ADORA1" 15 +"GO:0045851" "GO:0045851" "pH reduction" "16/743" "51/17381" 1.87384092237789e-10 5.77209926982474e-09 3.46355308334258e-09 "ATP6V1C1/AVPR1A/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/FASLG/ATP6AP1/ATP6V1G2/ATP6V0C/BCL2/ATP6V0B/ATP6V1E1/CA2/CA7/AVP" 16 +"GO:0030799" "GO:0030799" "regulation of cyclic nucleotide metabolic process" "29/743" "171/17381" 1.90204926093334e-10 5.79951164820446e-09 3.4800019043383e-09 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 29 +"GO:0007187" "GO:0007187" "G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger" "30/743" "182/17381" 1.90515358491741e-10 5.79951164820446e-09 3.4800019043383e-09 "ANXA1/ADRB2/AGT/ADCY1/CALCA/ADCY6/ADRA1D/ADRA1A/ADCY5/ADCY9/ADCY7/ADRA2B/ADRA2C/ADRB3/CASR/CALCR/APLP1/ADRA1B/ADRA2A/ADRB1/ADORA2B/CACNA1D/AGTR2/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2/ADORA1" 30 +"GO:0000082" "GO:0000082" "G1/S transition of mitotic cell cycle" "37/743" "265/17381" 2.11851977061515e-10 6.41130983212481e-09 3.84711192570927e-09 "ANXA1/BCAT1/CDKN1B/CDC25C/BID/AIF1/CDK1/CCNH/CDK4/CDK6/CDKN2D/CCNB1/AKT1/ACVR1B/BACH1/CCND2/CDK7/CASP2/CDK3/CDC34/CDC6/BAX/CDK2/CDKN2B/CAMK2G/CDKN1A/CCNE1/BCL2/ACVR1/ATM/CDKN2A/CDC25A/APEX1/CDKN3/CCND1/CAMK2A/CDKN2C" 37 +"GO:0046034" "GO:0046034" "ATP metabolic process" "37/743" "266/17381" 2.36287052600063e-10 7.10921800700772e-09 4.26589232050298e-09 "ATP5F1/ALDOC/ALDOA/BID/CDK1/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/ATP5O/ATP7A/ATP6V1B1/ACTN3/ATP6V1A/ATP5G3/BPGM/ATP1A2/ATP5D/ATP5J/AK1/ALDOB/ATP1B1/CBFA2T3/AK4/PARP1/ADCYAP1/ATP5G2/ATP5B/ATP5A1" 37 +"GO:0046058" "GO:0046058" "cAMP metabolic process" "28/743" "162/17381" 2.48376955842618e-10 7.42977310107253e-09 4.45824167773485e-09 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 28 +"GO:0070588" "GO:0070588" "calcium ion transmembrane transport" "40/743" "305/17381" 2.68758782558285e-10 7.99325689505244e-09 4.79636060826945e-09 "CASQ1/CALM1/APLNR/CACNB4/CACNA1C/CACNG1/BDKRB1/CALM3/ATP2B1/ATP2A2/ATP2B4/CAMK2D/CAV3/CALM2/CACNA1F/CAPN3/CACNA2D1/CALCR/BAX/CD19/ATP2B3/ADRA2A/ATP1A2/FASLG/CACNA1S/ATP2A3/CACNA1B/CACNA1D/ATP2A1/ATP1B1/CACNB1/ASIC1/CASQ2/ATP2B2/CACNA1E/ANK2/CACNB2/CACNA1A/CACNB3/ABL1" 40 +"GO:0006883" "GO:0006883" "cellular sodium ion homeostasis" "9/743" "13/17381" 2.786101588397e-10 8.23890041140256e-09 4.94375920948641e-09 "AGT/ATP1B3/ATP1A3/ATP1B2/ATP1A1/ATP1A2/C7/ATP1B1/AGTR2" 9 +"GO:0052547" "GO:0052547" "regulation of peptidase activity" "49/743" "426/17381" 2.82839327649296e-10 8.31644045786992e-09 4.99028718041521e-09 "APP/BIRC2/CASP1/BID/CASP9/FAS/AGT/CDKN2D/AKT1/SERPINH1/ASPH/ARRB1/BAD/BOK/SERPINA3/SERPINC1/CAST/CASP2/C5/CD27/FOXL2/A2M/BAX/ALOX12/FASLG/SERPINA6/ARRB2/XIAP/CASP8/CAV1/APLP2/C3/CCK/AQP1/BST2/BIRC3/CASP7/AMBP/ADORA2A/C4B/CASP3/BIRC5/AVP/C4A/CD44/APAF1/AHSG/SERPING1/BAK1" 49 +"GO:0097755" "GO:0097755" "positive regulation of blood vessel diameter" "17/743" "60/17381" 3.06005417815877e-10 8.9467685717354e-09 5.36851610203294e-09 "BDKRB2/BBS2/ADM/ADRB2/AGT/CALCA/APOE/ADRB3/CASR/BMPR2/ALOX12/ADRB1/ADORA2B/AGTR2/ADCYAP1/ADORA2A/ADORA1" 17 +"GO:1904064" "GO:1904064" "positive regulation of cation transmembrane transport" "24/743" "123/17381" 3.66792227043955e-10 1.06637627806318e-08 6.39879993956043e-09 "CASQ1/CALM1/APLNR/ADRB2/BDKRB1/CALM3/AGT/ATP1B3/ARF1/ACTN2/ATP1B2/CALM2/CAPN3/CACNA2D1/CALCR/BAX/CD19/ANK3/ATP1B1/ACTN4/ANK2/CACNB2/ABL1/B2M" 24 +"GO:0042311" "GO:0042311" "vasodilation" "13/743" "33/17381" 3.72398133855694e-10 1.07662588977833e-08 6.46030282195999e-09 "BDKRB2/BBS2/ADRB2/AGT/CALCA/APOE/ADRB3/CASR/ADRB1/ADORA2B/AGTR2/ADORA2A/ADORA1" 13 +"GO:0071214" "GO:0071214" "cellular response to abiotic stimulus" "39/743" "296/17381" 3.92936608290315e-10 1.12345135243225e-08 6.74127940945874e-09 "BDKRB2/CASP1/CALM1/ATR/AQP2/AVPR1A/CASP9/AKT2/FAS/AGT/AKT1/CCND2/TSPO/BAD/CASP5/ATP1A1/CASP2/ASCL1/CAPN3/BAX/ATP1A2/TNFRSF8/CDKN1A/CASP8/CD40/BLM/ATM/AQP1/RHOB/ASIC1/BMP6/ZFP36L1/CASP3/CDC25A/BCL2L1/BNIP3/ADSS/ATF4/BAK1" 39 +"GO:0104004" "GO:0104004" "cellular response to environmental stimulus" "39/743" "296/17381" 3.92936608290315e-10 1.12345135243225e-08 6.74127940945874e-09 "BDKRB2/CASP1/CALM1/ATR/AQP2/AVPR1A/CASP9/AKT2/FAS/AGT/AKT1/CCND2/TSPO/BAD/CASP5/ATP1A1/CASP2/ASCL1/CAPN3/BAX/ATP1A2/TNFRSF8/CDKN1A/CASP8/CD40/BLM/ATM/AQP1/RHOB/ASIC1/BMP6/ZFP36L1/CASP3/CDC25A/BCL2L1/BNIP3/ADSS/ATF4/BAK1" 39 +"GO:0060193" "GO:0060193" "positive regulation of lipase activity" "17/743" "61/17381" 4.07543723782913e-10 1.15881251130581e-08 6.95346434447422e-09 "APOC2/ARF4/ABL2/AVPR1A/AGT/AVPR1B/ADRA1A/APOA4/ANG/ADCYAP1R1/APOA1/AGTR1/RHOC/ARL1/APOH/RHOA/C5AR1" 17 +"GO:0034762" "GO:0034762" "regulation of transmembrane transport" "51/743" "459/17381" 4.17188185212596e-10 1.1797534745766e-08 7.07912077294886e-09 "APP/CASQ1/CALM1/APLNR/CACNB4/ADRB2/CACNA1C/CACNG1/BDKRB1/CALM3/AKT2/AGT/ATP1B3/AKT1/ASIC2/ARF1/ACTN2/ATP2B4/ATP1B2/CAMK2D/CAV3/CALM2/ATP7A/CACNA1F/CAPN3/CACNA2D1/CALCR/FXYD2/BAX/CD19/ADRA2A/ATP1A2/CACNA1S/CAV1/BCL2/ANK3/CACNA1B/CACNA1D/ATP1B1/HCN2/CACNB1/CASQ2/ACTN4/CACNA1E/ANK2/CA2/CACNB2/CACNA1A/CACNB3/ABL1/B2M" 51 +"GO:0006956" "GO:0006956" "complement activation" "27/743" "155/17381" 4.33280058675416e-10 1.21201313710556e-08 7.27269515273102e-09 "CFB/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/CD81/C5/C1R/A2M/CD19/C1QB/C8B/C7/C4BPB/C3/C9/C5AR1/C4B/C1QC/C4A/CD59/C1QBP/SERPING1" 27 +"GO:0007188" "GO:0007188" "adenylate cyclase-modulating G-protein coupled receptor signaling pathway" "27/743" "155/17381" 4.33280058675416e-10 1.21201313710556e-08 7.27269515273102e-09 "ADRB2/ADCY1/CALCA/ADCY6/ADRA1D/ADRA1A/ADCY5/ADCY9/ADCY7/ADRA2B/ADRA2C/ADRB3/CASR/CALCR/APLP1/ADRA1B/ADRA2A/ADRB1/ADORA2B/CACNA1D/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2/ADORA1" 27 +"GO:0060402" "GO:0060402" "calcium ion transport into cytosol" "26/743" "145/17381" 4.74912618334944e-10 1.32132946230287e-08 7.92864869319799e-09 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CD4/CALM3/ADRA1A/ATP2B4/CAMK2D/CALM2/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ATP1A2/FASLG/CAV1/BCL2/CASQ2/ANK2/CACNB3/ABL1/BAK1" 26 +"GO:0072376" "GO:0072376" "protein activation cascade" "29/743" "178/17381" 5.09020017017922e-10 1.40865165137313e-08 8.45262623249574e-09 "CFB/C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C3AR1/CD81/SERPINC1/C5/C1R/A2M/CD19/C1QB/C8B/C7/C4BPB/C3/APOH/C9/C5AR1/C4B/C1QC/C4A/CD59/C1QBP/SERPING1" 29 +"GO:0034367" "GO:0034367" "macromolecular complex remodeling" "12/743" "28/17381" 5.52200131741594e-10 1.49614433600144e-08 8.97762683184184e-09 "APOC2/APOC3/SCARB1/AGT/ALB/APOE/APOA4/APOA1/AGTR1/APOA2/APOC1/APOB" 12 +"GO:0034368" "GO:0034368" "protein-lipid complex remodeling" "12/743" "28/17381" 5.52200131741594e-10 1.49614433600144e-08 8.97762683184184e-09 "APOC2/APOC3/SCARB1/AGT/ALB/APOE/APOA4/APOA1/AGTR1/APOA2/APOC1/APOB" 12 +"GO:0034369" "GO:0034369" "plasma lipoprotein particle remodeling" "12/743" "28/17381" 5.52200131741594e-10 1.49614433600144e-08 8.97762683184184e-09 "APOC2/APOC3/SCARB1/AGT/ALB/APOE/APOA4/APOA1/AGTR1/APOA2/APOC1/APOB" 12 +"GO:0034377" "GO:0034377" "plasma lipoprotein particle assembly" "12/743" "28/17381" 5.52200131741594e-10 1.49614433600144e-08 8.97762683184184e-09 "APOC2/APOC3/APOC4/APOE/ARF1/APOA4/ABCA1/APOA1/BMP1/APOA2/APOC1/APOB" 12 +"GO:0060401" "GO:0060401" "cytosolic calcium ion transport" "27/743" "157/17381" 5.83496687528746e-10 1.57270591560482e-08 9.43703524237829e-09 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CD4/CALM3/ATP2A2/ADRA1A/ATP2B4/CAMK2D/CALM2/CAPN3/CACNA2D1/CALCR/BAX/ADCYAP1R1/CD19/ATP1A2/FASLG/CAV1/BCL2/CASQ2/ANK2/CACNB3/ABL1/BAK1" 27 +"GO:0002027" "GO:0002027" "regulation of heart rate" "21/743" "97/17381" 6.23525113526087e-10 1.66326931056572e-08 9.98046166523036e-09 "CALM1/ADM/CACNA1C/AVPR1A/CALM3/AGT/CALCA/ATP2A2/ADRA1A/CAMK2D/CAV3/CALM2/CACNA2D1/ADA/ADRB1/CAV1/CACNA1D/AGTR2/CASQ2/ANK2/CACNB2" 21 +"GO:0010522" "GO:0010522" "regulation of calcium ion transport into cytosol" "21/743" "97/17381" 6.23525113526087e-10 1.66326931056572e-08 9.98046166523036e-09 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CD4/CALM3/CAMK2D/CALM2/CAPN3/CALCR/BAX/ADCYAP1R1/CD19/ATP1A2/CAV1/BCL2/CASQ2/ANK2/ABL1/BAK1" 21 +"GO:0048732" "GO:0048732" "gland development" "48/743" "422/17381" 6.31438155053347e-10 1.67553290707289e-08 1.00540494805289e-08 "CDO1/ANXA1/BMP2/CDKN1B/ARHGAP5/BRCA2/DDR1/BAAT/AKT2/ACAT1/AKT1/BMPR1A/TSPO/AR/NR0B1/SERPINC1/ASCL1/CAV3/AREG/AIRE/ATP7A/CDC42/BAX/APOA1/ADA/CAPN1/BMP7/ACO2/APRT/CAV1/BCL2/BRAF/CCKBR/ALDH1A3/CEACAM1/ATM/AK4/ARF6/ADCYAP1/CDKN1C/CDH1/ATP7B/ASNS/ARG1/BMP4/CCND1/ABL1/ALOX15B" 48 +"GO:0071496" "GO:0071496" "cellular response to external stimulus" "38/743" "288/17381" 6.34597970601521e-10 1.67553290707289e-08 1.00540494805289e-08 "CASP1/AIF1/AQP2/AXL/AES/AVPR1A/FAS/AGT/AKT1/ALB/ATP2B1/BAD/CASP5/BGLAP/ATP1A1/AOC1/CASP2/CASR/BMPR2/CBS/ATP1A2/TNFRSF8/CDKN2B/CDKN1A/ADORA2B/CASP8/BCL2/AQP3/ATF3/CD40/AQP1/BMP6/ASNS/BNIP3/ATF4/CBL/ASGR1/BAK1" 38 +"GO:0002460" "GO:0002460" "adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" "40/743" "314/17381" 6.46640486863643e-10 1.69866219264942e-08 1.01928369556385e-08 "ANXA1/C4BPA/C2/C8A/C8G/C1QA/CD4/C6/FAS/CD74/AGER/C1S/CD80/BTK/C5/CD27/AIRE/C1R/ADA/CD8A/C1QB/C8B/C7/CD40/BCL6/C4BPB/C3/C9/BCL3/CEACAM1/C4B/C1QC/C4A/ARG1/CD28/JAG1/CD40LG/C1QBP/SERPING1/B2M" 40 +"GO:0086065" "GO:0086065" "cell communication involved in cardiac conduction" "16/743" "55/17381" 6.61972950954357e-10 1.73015657635798e-08 1.03818192733405e-08 "CALM1/CACNA1C/CALM3/ATP1A3/ATP1B2/ATP1A1/CAMK2D/CALM2/CACNA2D1/ATP1A2/CAV1/CACNA1D/ATP1B1/CASQ2/ANK2/CACNB2" 16 +"GO:0009187" "GO:0009187" "cyclic nucleotide metabolic process" "31/743" "203/17381" 6.76764635095433e-10 1.75992813397933e-08 1.05604637584318e-08 "CALM1/ADM/ADRB2/CALM3/ADCY1/CALCA/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA3/CALM2/ADRB3/ABCA1/CALCR/APLP1/ADCYAP1R1/ADRA2A/ADRB1/ADORA2B/ACR/AMPD2/AQP1/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/AVP/ADCY2" 31 +"GO:0086064" "GO:0086064" "cell communication by electrical coupling involved in cardiac conduction" "11/743" "23/17381" 6.84047807679066e-10 1.76997370236958e-08 1.06207422771223e-08 "CALM1/CACNA1C/CALM3/ATP1A3/ATP1B2/ATP1A1/CAMK2D/CALM2/ATP1A2/CAV1/ATP1B1" 11 +"GO:0050891" "GO:0050891" "multicellular organismal water homeostasis" "17/743" "63/17381" 7.09703988080421e-10 1.82222526058733e-08 1.09342781972695e-08 "AQP2/ADCY1/ADCY6/ADCY5/ADCY9/ADCY7/AQP4/ALOX12/AQP3/AKR1B1/AQP1/ALOX12B/ADCY8/ADCY3/AVPR2/AVP/ADCY2" 17 +"GO:0051235" "GO:0051235" "maintenance of location" "39/743" "302/17381" 7.11284063069836e-10 1.82222526058733e-08 1.09342781972695e-08 "CASQ1/CALM1/APLNR/APOC4/CACNA1C/BDKRB1/CD4/SCARB1/CALM3/AKT1/ALB/TSPO/APOE/CAMK2D/CALM2/CD27/ABCA1/BBS4/CD36/CAPN3/BAX/ARL2/APOA1/CD19/ATP1A2/FASLG/CAV1/ANK3/C3/ATP2A1/BCL3/ACACB/CALR/CASQ2/ATP7B/PLIN2/ANK2/APOB/ABL1" 39 +"GO:0006754" "GO:0006754" "ATP biosynthetic process" "15/743" "48/17381" 7.40859100884485e-10 1.88864327442227e-08 1.13328200550129e-08 "ATP5F1/ALDOA/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/PARP1/ATP5G2/ATP5B/ATP5A1" 15 +"GO:0009144" "GO:0009144" "purine nucleoside triphosphate metabolic process" "39/743" "303/17381" 7.8386863139335e-10 1.98849027816695e-08 1.19319528514468e-08 "ATP5F1/ALDOC/ALDOA/BID/CDK1/ADK/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/ATP5O/ATP7A/ATP6V1B1/ACTN3/ATP6V1A/ATP5G3/ADA/BPGM/ATP1A2/ATP5D/ATP5J/AK1/ALDOB/ATP1B1/CBFA2T3/AK4/PARP1/ADCYAP1/ATP5G2/ATP5B/ATP5A1" 39 +"GO:0003073" "GO:0003073" "regulation of systemic arterial blood pressure" "20/743" "89/17381" 7.9160110182945e-10 1.99831009852068e-08 1.19908767671213e-08 "ADM/ADRB2/AVPR1A/AGT/AVPR1B/CALCA/ASIC2/ADRA1D/ADRA1A/AR/ADRB3/BBS4/BMPR2/AGTR1/ADRA1B/ADRB1/AGTR2/AVPR2/AVP/ADORA1" 20 +"GO:0015711" "GO:0015711" "organic anion transport" "50/743" "455/17381" 9.12298886153188e-10 2.29181880380716e-08 1.37520782532034e-08 "ANXA1/BDKRB2/APOC2/SLC25A6/APOC3/AVPR1A/SCARB1/AKT2/AGT/AKT1/ALB/CA9/APOE/APBA1/CA6/SLC25A5/APOA4/ACACA/ABCD2/BSG/ABCA1/CD36/APOA1/ATP1A2/CA3/CA4/ABAT/AQP9/CCK/ACACB/APOA2/AGTR2/CEACAM1/AQP1/CA12/ADORA2A/ABCA4/PLIN2/CA2/CA7/AVP/APOC1/ARG1/ABCD1/CA1/SLC25A4/CA5A/AGXT/ADORA1/SLC25A20" 50 +"GO:0034764" "GO:0034764" "positive regulation of transmembrane transport" "25/743" "139/17381" 9.59224327369803e-10 2.39806081842451e-08 1.43895843668493e-08 "CASQ1/CALM1/APLNR/ADRB2/BDKRB1/CALM3/AGT/ATP1B3/ARF1/ACTN2/ATP1B2/CALM2/CAPN3/CACNA2D1/CALCR/BAX/CD19/ANK3/ATP1B1/ACTN4/ANK2/CA2/CACNB2/ABL1/B2M" 25 +"GO:0007159" "GO:0007159" "leukocyte cell-cell adhesion" "44/743" "374/17381" 1.15740701413364e-09 2.87960639333731e-08 1.72791026907604e-08 "ANXA1/AIF1/CD6/CD3G/CD4/ARG2/CD74/AKT1/CD47/AGER/RUNX1/CD80/BAD/APOA4/CD247/CD3E/CD27/ADD2/CD3D/PRDM1/CDC42/ADA/BMP7/CAV1/BRAF/BCL6/CBFB/ASS1/CD2/CEACAM1/CAMK4/ADORA2A/CASP3/CD5/CD59/CD44/ARG1/CD28/ADAM8/CD1D/CD40LG/BMP4/CD86/ABL1" 44 +"GO:0034765" "GO:0034765" "regulation of ion transmembrane transport" "49/743" "444/17381" 1.16893489282391e-09 2.89437228247069e-08 1.73677055342762e-08 "APP/CASQ1/CALM1/APLNR/CACNB4/ADRB2/CACNA1C/CACNG1/BDKRB1/CALM3/AKT2/AGT/ATP1B3/AKT1/ASIC2/ARF1/ACTN2/ATP2B4/ATP1B2/CAMK2D/CAV3/CALM2/ATP7A/CACNA1F/CAPN3/CACNA2D1/CALCR/FXYD2/BAX/CD19/ADRA2A/ATP1A2/CACNA1S/CAV1/ANK3/CACNA1B/CACNA1D/ATP1B1/HCN2/CACNB1/CASQ2/ACTN4/CACNA1E/ANK2/CACNB2/CACNA1A/CACNB3/ABL1/B2M" 49 +"GO:0006942" "GO:0006942" "regulation of striated muscle contraction" "20/743" "91/17381" 1.2034062962717e-09 2.96553694438383e-08 1.77947296942432e-08 "CASQ1/CALM1/CACNA1C/CALM3/ATP2A2/ADRA1A/ATP1A1/CAMK2D/CAV3/CALM2/ACTN3/ADRA1B/ATP1A2/CAV1/ATP2A1/ATP1B1/CASQ2/GRK2/ANK2/ADORA1" 20 +"GO:0006959" "GO:0006959" "humoral immune response" "40/743" "321/17381" 1.24708186903567e-09 3.04985663211002e-08 1.83006906986515e-08 "CFB/C4BPA/C2/C8A/KLK3/C8G/C1QA/BPI/C6/AZU1/C1S/C3AR1/CD81/ATOX1/C5/AIRE/ATP7A/C1R/A2M/CD19/C1QB/C8B/C7/CAMP/BCL2/C4BPB/C3/C9/BCL3/BST1/BST2/C5AR1/C4B/C1QC/MS4A1/C4A/CD59/CD28/C1QBP/SERPING1" 40 +"GO:0006833" "GO:0006833" "water transport" "10/743" "19/17381" 1.24940986668082e-09 3.04985663211002e-08 1.83006906986515e-08 "AQP6/AQP2/AQP8/AQP7/AQP4/AQP3/AQP9/AQP1/AVP/AQP5" 10 +"GO:0009141" "GO:0009141" "nucleoside triphosphate metabolic process" "40/743" "322/17381" 1.36729898655471e-09 3.32195880536181e-08 1.99334421069257e-08 "ATP5F1/ALDOC/ALDOA/BID/CDK1/ADK/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ENTPD3/ARNT/AMPD3/BAD/ATP5I/ATP5O/ATP7A/ATP6V1B1/ACTN3/ATP6V1A/ATP5G3/ADA/BPGM/ATP1A2/ATP5D/ATP5J/AK1/ALDOB/ATP1B1/CBFA2T3/AK4/PARP1/ADCYAP1/ATP5G2/ATP5B/ATP5A1" 40 +"GO:0051452" "GO:0051452" "intracellular pH reduction" "15/743" "50/17381" 1.4082214989824e-09 3.40539544730556e-08 2.0434104387595e-08 "ATP6V1C1/AVPR1A/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/FASLG/ATP6V1G2/ATP6V0C/BCL2/ATP6V0B/ATP6V1E1/CA2/CA7/AVP" 15 +"GO:0042407" "GO:0042407" "cristae formation" "12/743" "30/17381" 1.45074748374351e-09 3.49191545505706e-08 2.09532684310569e-08 "ATP5F1/ATP5C1/ATP5G1/ATP5E/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/ATP5G2/ATP5B/ATP5A1" 12 +"GO:0071248" "GO:0071248" "cellular response to metal ion" "26/743" "153/17381" 1.58413343208453e-09 3.79531968103586e-08 2.277384807334e-08 "CDKN1B/AQP2/FAS/ADCY1/CCNB1/AKT1/TSPO/AOC1/ADD1/CAMK2D/ATP7A/CAPN3/ALAD/ALOX15/BRAF/ANK3/CALR/AQP1/PARP1/BMP6/CDH1/ALOX5AP/BNIP3/ATF4/CD86/B2M" 26 +"GO:0050994" "GO:0050994" "regulation of lipid catabolic process" "15/743" "51/17381" 1.91690375179265e-09 4.55685321435734e-08 2.73434365265277e-08 "APOC2/APOC3/CDK4/SCARB1/AKT2/AKT1/APOA4/ABCD2/AADAC/APOA1/ADRA2A/ACACB/APOA2/APOC1/ADORA1" 15 +"GO:0060627" "GO:0060627" "regulation of vesicle-mediated transport" "50/743" "465/17381" 1.91960193377759e-09 4.55685321435734e-08 2.73434365265277e-08 "ANXA1/APOC2/C4BPA/C2/ANXA2/APOC3/AXL/ABL2/SCARB1/AKT2/CD47/AZU1/BIN1/ATP2A2/APOE/ARRB1/ARF1/ACTN2/ABR/BCR/AP1G1/CAV3/CD36/ADRA2A/ATP6AP1/ALOX15/ADORA2B/ARRB2/CAV1/BRAF/C4BPB/C3/BICD1/CD63/CEACAM1/CD14/CALR/ARF6/ACTN4/C4B/CDK5/APOC1/C4A/CDH13/AHSG/ARHGAP1/ABL1/CBL/B2M/ANGPT1" 50 +"GO:0034767" "GO:0034767" "positive regulation of ion transmembrane transport" "24/743" "133/17381" 1.93664786096696e-09 4.57632542488768e-08 2.74602796916728e-08 "CASQ1/CALM1/APLNR/ADRB2/BDKRB1/CALM3/AGT/ATP1B3/ARF1/ACTN2/ATP1B2/CALM2/CAPN3/CACNA2D1/CALCR/BAX/CD19/ANK3/ATP1B1/ACTN4/ANK2/CACNB2/ABL1/B2M" 24 +"GO:0007588" "GO:0007588" "excretion" "17/743" "67/17381" 2.0118140887488e-09 4.73233541330683e-08 2.83964189560237e-08 "AQP6/AQP2/AVPR1A/AQP7/AGT/ADRA1A/ATP6V1B1/AGTR1/ADORA2B/AQP3/AQP9/AGTR2/ADORA2A/AVPR2/AVP/AQP5/ADORA1" 17 +"GO:0048771" "GO:0048771" "tissue remodeling" "27/743" "166/17381" 2.09128244222339e-09 4.89700752873577e-08 2.93845353872779e-08 "ANXA1/ADRB2/ACVR2B/AXL/ACVRL1/AGT/CALCA/AGER/ACP5/BGLAP/ABR/BCR/ATP7A/BMPR2/BGN/BAX/CAPN1/ATP6AP1/CAV1/CD38/AGTR2/CEACAM1/CA2/ARG1/ADAM8/JAG1/BAK1" 27 +"GO:0009142" "GO:0009142" "nucleoside triphosphate biosynthetic process" "18/743" "76/17381" 2.25641048228129e-09 5.25987578639894e-08 3.15619294581783e-08 "ATP5F1/ALDOA/ADK/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/AK1/AK4/PARP1/ATP5G2/ATP5B/ATP5A1" 18 +"GO:0010524" "GO:0010524" "positive regulation of calcium ion transport into cytosol" "15/743" "52/17381" 2.58860612826675e-09 6.00719135147105e-08 3.60462028717815e-08 "CASQ1/CALM1/APLNR/BDKRB1/CD4/CALM3/CALM2/CAPN3/CALCR/BAX/ADCYAP1R1/CD19/CAV1/ABL1/BAK1" 15 +"GO:1903037" "GO:1903037" "regulation of leukocyte cell-cell adhesion" "41/743" "343/17381" 2.69124608762917e-09 6.21749933191114e-08 3.73081576997465e-08 "ANXA1/AIF1/CD6/CD3G/CD4/ARG2/CD74/AKT1/CD47/AGER/RUNX1/CD80/BAD/CD247/CD3E/CD27/CD3D/PRDM1/CDC42/ADA/CAV1/BRAF/BCL6/CBFB/ASS1/CD2/CEACAM1/CAMK4/ADORA2A/CASP3/CD5/CD59/CD44/ARG1/CD28/ADAM8/CD1D/CD40LG/BMP4/CD86/ABL1" 41 +"GO:0031279" "GO:0031279" "regulation of cyclase activity" "20/743" "96/17381" 3.25470141909578e-09 7.48581326392029e-08 4.49186862518482e-08 "ADRB2/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/ADRB3/CALCR/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2" 20 +"GO:1903524" "GO:1903524" "positive regulation of blood circulation" "17/743" "69/17381" 3.28499784941538e-09 7.52206365961266e-08 4.51362070599692e-08 "ADM/AVPR1A/AVPR1B/AKT1/ATP2A2/ADRA1D/ADRA1A/ATP1A1/ADRA2C/CASR/ADRA1B/ADA/ADRB1/CAV1/CD38/AVPR2/AVP" 17 +"GO:0071875" "GO:0071875" "adrenergic receptor signaling pathway" "11/743" "26/17381" 3.4744175313295e-09 7.92075362318509e-08 4.75285495822955e-08 "ADRB2/ADRA1D/ADRA1A/ADCY9/ATP2B4/ADRA2B/ADRA2C/ADRB3/ADRA1B/ADRA2A/ADRB1" 11 +"GO:0009145" "GO:0009145" "purine nucleoside triphosphate biosynthetic process" "16/743" "61/17381" 3.54923791917452e-09 8.05583606654742e-08 4.8339112934279e-08 "ATP5F1/ALDOA/ADK/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/PARP1/ATP5G2/ATP5B/ATP5A1" 16 +"GO:0015850" "GO:0015850" "organic hydroxy compound transport" "32/743" "230/17381" 3.88557932959428e-09 8.78073058107004e-08 5.26888486430849e-08 "APOC2/ANXA2/APOC3/AQP2/SCARB1/AQP7/AGT/ALB/ABCA2/TSPO/APOE/APOA4/ADRA2B/ADRA2C/ABCA1/CD36/APOA1/AGTR1/ADRA2A/CAV1/AQP3/ABAT/AQP9/APOA2/AGTR2/CEACAM1/AQP1/BMP6/ADORA2A/GRK2/APOC1/APOB" 32 +"GO:0051339" "GO:0051339" "regulation of lyase activity" "20/743" "97/17381" 3.93812383612687e-09 8.86077863128546e-08 5.31691776502255e-08 "ADRB2/ADCY1/CALCA/ADCY6/ADCY5/ADCY9/ADCY7/ADORA3/ADRB3/CALCR/ADRA2A/ADRB1/ADORA2B/ACR/ADCY8/ADCY3/ADCYAP1/ADORA2A/AVPR2/ADCY2" 20 +"GO:0046651" "GO:0046651" "lymphocyte proliferation" "35/743" "268/17381" 3.97998796749921e-09 8.91620681030667e-08 5.35017749105612e-08 "ANXA1/AIF1/CD6/CD4/ARG2/CD74/CD79A/AGER/CD80/BTK/CD81/CD3E/PRDM1/BAX/ADA/CDKN1A/CD151/BCL2/CD40/BCL6/CD38/ATM/CCND3/BST1/AHR/CASP3/MS4A1/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86/ABL1" 35 +"GO:0001974" "GO:0001974" "blood vessel remodeling" "14/743" "46/17381" 4.04880878289416e-09 9.03128683253331e-08 5.4192313564146e-08 "ACVR2B/AXL/ACVRL1/AGT/ABR/BCR/ATP7A/BMPR2/BGN/BAX/AGTR2/CEACAM1/JAG1/BAK1" 14 +"GO:0043281" "GO:0043281" "regulation of cysteine-type endopeptidase activity involved in apoptotic process" "30/743" "207/17381" 4.52877988210663e-09 1.00518817666302e-07 6.03164021592862e-08 "BIRC2/CASP1/BID/CASP9/FAS/CDKN2D/AKT1/ARRB1/BAD/BOK/CASP2/CD27/FOXL2/BAX/ALOX12/FASLG/ARRB2/XIAP/CASP8/CCK/AQP1/BIRC3/CASP7/ADORA2A/CASP3/BIRC5/AVP/CD44/APAF1/BAK1" 30 +"GO:0050863" "GO:0050863" "regulation of T cell activation" "39/743" "322/17381" 4.54519871186757e-09 1.00518817666302e-07 6.03164021592862e-08 "ANXA1/AIF1/CD6/CD3G/CD4/ARG2/CD74/AKT1/CD47/AGER/RUNX1/CD80/BAD/CD247/CD3E/CD27/CD3D/PRDM1/CDC42/ADA/CAV1/BRAF/BCL6/CBFB/CD2/CEACAM1/CAMK4/ADORA2A/CASP3/CD5/CD59/ARG1/CD28/ADAM8/CD1D/CD40LG/BMP4/CD86/ABL1" 39 +"GO:0033700" "GO:0033700" "phospholipid efflux" "8/743" "12/17381" 4.56721525396029e-09 1.00575910379764e-07 6.03506606906288e-08 "APOC2/APOC3/APOE/APOA4/ABCA1/APOA1/APOA2/APOC1" 8 +"GO:0006941" "GO:0006941" "striated muscle contraction" "27/743" "172/17381" 4.6447980062371e-09 1.01850973229987e-07 6.11157632399618e-08 "ALDOA/CASQ1/CALM1/CACNA1C/ARG2/CALM3/ATP2A2/ADRA1A/ATP1A3/ATP1A1/CAMK2D/CAV3/CALM2/CACNA2D1/ACTN3/ADRA1B/ATP1A2/CAV1/CACNA1D/ACTC1/ATP2A1/ATP1B1/CASQ2/GRK2/ANK2/CACNB2/ADORA1" 27 +"GO:0009205" "GO:0009205" "purine ribonucleoside triphosphate metabolic process" "37/743" "296/17381" 4.81094501590655e-09 1.05049115853656e-07 6.30348114453667e-08 "ATP5F1/ALDOC/ALDOA/BID/CDK1/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/ATP5O/ATP7A/ATP6V1B1/ACTN3/ATP6V1A/ATP5G3/BPGM/ATP1A2/ATP5D/ATP5J/AK1/ALDOB/ATP1B1/CBFA2T3/AK4/PARP1/ADCYAP1/ATP5G2/ATP5B/ATP5A1" 37 +"GO:0032943" "GO:0032943" "mononuclear cell proliferation" "35/743" "270/17381" 4.846582071974e-09 1.05382614380107e-07 6.32349275202269e-08 "ANXA1/AIF1/CD6/CD4/ARG2/CD74/CD79A/AGER/CD80/BTK/CD81/CD3E/PRDM1/BAX/ADA/CDKN1A/CD151/BCL2/CD40/BCL6/CD38/ATM/CCND3/BST1/AHR/CASP3/MS4A1/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86/ABL1" 35 +"GO:0045907" "GO:0045907" "positive regulation of vasoconstriction" "12/743" "33/17381" 5.28674611363608e-09 1.14472431540028e-07 6.86892800494448e-08 "AVPR1A/AVPR1B/AKT1/ADRA1D/ADRA1A/ADRA2C/CASR/ADRA1B/CAV1/CD38/AVPR2/AVP" 12 +"GO:0045833" "GO:0045833" "negative regulation of lipid metabolic process" "18/743" "80/17381" 5.44750836667543e-09 1.17461899156439e-07 7.04831126390022e-08 "BMP2/APOC2/APOC3/AKT1/APOE/ATP1A1/ADRA2A/ACADVL/ACADL/ACACB/APOA2/CEACAM1/APOBEC1/BMP5/APOD/BRCA1/APOC1/ADORA1" 18 +"GO:0051402" "GO:0051402" "neuron apoptotic process" "31/743" "221/17381" 5.5801877159196e-09 1.19823532904083e-07 7.19002129808379e-08 "AARS/APP/BID/AXL/CASP9/AKT2/FAS/APOE/BOK/CASP2/ASCL1/CDC34/CDC42/BAX/BDNF/ADARB1/FASLG/BCL2/BRAF/ATM/PARP1/C5AR1/ADORA2A/CASP3/CDK5/APAF1/ADAM8/BCL2L1/BNIP3/ATF4/ANGPT1" 31 +"GO:1904645" "GO:1904645" "response to amyloid-beta" "11/743" "27/17381" 5.63740228618385e-09 1.20551887731411e-07 7.23372629153648e-08 "APP/CASP4/ADRB2/AGER/ATP1A3/CD36/CACNA2D1/CACNB1/PARP1/CDK5/CACNA1A" 11 +"GO:0019724" "GO:0019724" "B cell mediated immunity" "29/743" "197/17381" 5.69896823807402e-09 1.21366916181206e-07 7.28263214308787e-08 "C4BPA/C2/C8A/C8G/C1QA/C6/FAS/CD74/C1S/BTK/C5/CD27/C1R/C1QB/C8B/C7/CD40/BCL6/C4BPB/C3/C9/BCL3/C4B/C1QC/C4A/CD28/CD40LG/C1QBP/SERPING1" 29 +"GO:0007599" "GO:0007599" "hemostasis" "41/743" "353/17381" 6.26873870150537e-09 1.32953781886436e-07 7.97790300666128e-08 "ANXA2/AXL/AKT1/ASIC2/APOE/ARRB1/CD34/ADRA2B/CD9/ANXA7/SERPINC1/ADRA2C/CAPZB/CD36/A2M/CDC42/ACTB/ALOX12/RHOG/ADRA2A/ACTG1/ARRB2/CAV1/ABAT/CD40/CAPZA2/C4BPB/APOH/CAPZA1/RHOA/CEACAM1/ENTPD2/RHOB/ENTPD1/ADORA2A/ANXA5/AVPR2/CD59/CD40LG/C1QBP/SERPING1" 41 +"GO:0002449" "GO:0002449" "lymphocyte mediated immunity" "38/743" "314/17381" 7.34682467814993e-09 1.5514409546607e-07 9.30943466310514e-08 "C4BPA/C2/C8A/C8G/C1QA/C6/FAS/CD74/AGER/C1S/BTK/AP1G1/C5/CD27/AIRE/C1R/CD8A/C1QB/C8B/C7/ARRB2/CD40/BCL6/C4BPB/C3/C9/BCL3/CEACAM1/C4B/C1QC/C4A/ARG1/CD28/JAG1/CD40LG/C1QBP/SERPING1/B2M" 38 +"GO:2000116" "GO:2000116" "regulation of cysteine-type endopeptidase activity" "32/743" "236/17381" 7.37496569751753e-09 1.5514409546607e-07 9.30943466310514e-08 "BIRC2/CASP1/BID/CASP9/FAS/CDKN2D/AKT1/ASPH/ARRB1/BAD/BOK/CAST/CASP2/CD27/FOXL2/BAX/ALOX12/FASLG/ARRB2/XIAP/CASP8/CCK/AQP1/BIRC3/CASP7/ADORA2A/CASP3/BIRC5/AVP/CD44/APAF1/BAK1" 32 +"GO:1903169" "GO:1903169" "regulation of calcium ion transmembrane transport" "24/743" "142/17381" 7.51595971098045e-09 1.5747000609038e-07 9.44900112823027e-08 "CASQ1/CALM1/APLNR/CACNB4/CACNA1C/BDKRB1/CALM3/CAMK2D/CAV3/CALM2/CAPN3/CACNA2D1/CALCR/BAX/CD19/ADRA2A/ATP1A2/ATP1B1/CACNB1/CASQ2/ANK2/CACNB2/CACNB3/ABL1" 24 +"GO:0009199" "GO:0009199" "ribonucleoside triphosphate metabolic process" "37/743" "301/17381" 7.6011841383043e-09 1.58613419015019e-07 9.51761171816541e-08 "ATP5F1/ALDOC/ALDOA/BID/CDK1/ENTPD5/CCNB1/ATP5C1/ATP5G1/ATP6V1B2/ATP5E/TSPO/ATP6V0A1/ARNT/AMPD3/BAD/ATP5I/ATP5O/ATP7A/ATP6V1B1/ACTN3/ATP6V1A/ATP5G3/BPGM/ATP1A2/ATP5D/ATP5J/AK1/ALDOB/ATP1B1/CBFA2T3/AK4/PARP1/ADCYAP1/ATP5G2/ATP5B/ATP5A1" 37 +"GO:0051051" "GO:0051051" "negative regulation of transport" "51/743" "500/17381" 7.94061987029896e-09 1.65030955135731e-07 9.90269651971335e-08 "ANXA1/APOC2/CALM1/APOC3/ANXA4/ARG2/CALM3/AKT2/CD74/AKT1/SLC25A5/CD34/ACTN2/ABR/BOK/ADRA2B/BCR/CAMK2D/CAV3/ADRA2C/CALM2/CD27/CD36/ATP7A/APOA1/ADA/ADRA2A/ATP1A2/BMP7/CAV1/BCL2/ABAT/BRAF/BARD1/ANK3/APOA2/AGTR2/CEACAM1/ARF6/ASIC1/BST2/CASQ2/ADCYAP1/APOD/CDK5/AVPR2/APOC1/ARHGAP1/ATF4/ANGPT1/ADORA1" 51 +"GO:0006631" "GO:0006631" "fatty acid metabolic process" "41/743" "356/17381" 8.0196701184858e-09 1.66007171452656e-07 9.96127446296131e-08 "ANXA1/APOC2/APOC3/AVPR1A/ACOX1/BAAT/AKT2/CD74/ACAT1/ACAT2/AKT1/APOA4/ACACA/AUH/ACLY/ABCD2/ACADM/ALDH3A2/ACADSB/APOA1/ALOX12/ADH7/ALOX15/CBR1/CAV1/ACADVL/ACADL/C3/ACACB/CEACAM1/ACAA1/ALOX12B/BRCA1/AVP/APOC1/ALOX5/DAGLA/ALOX5AP/ACADS/ABCD1/ALOX15B" 41 +"GO:0034375" "GO:0034375" "high-density lipoprotein particle remodeling" "9/743" "17/17381" 8.11449020008303e-09 1.67300744165058e-07 1.00388954037513e-07 "APOC2/APOC3/SCARB1/ALB/APOE/APOA4/APOA1/APOA2/APOC1" 9 +"GO:0045471" "GO:0045471" "response to ethanol" "23/743" "132/17381" 8.4545469981468e-09 1.73620161569086e-07 1.04180925833471e-07 "CDO1/BIRC2/CDK1/BAD/ADCY7/BGLAP/CD27/ALAD/ADCYAP1R1/CAT/ADH7/ADH6/CA3/CASP8/ABAT/ACTC1/CD14/ADCYAP1/APOBEC1/AVP/CCND1/CBL/BAK1" 23 +"GO:0010594" "GO:0010594" "regulation of endothelial cell migration" "24/743" "143/17381" 8.67370768270981e-09 1.77416748055428e-07 1.06459070788408e-07 "ACVRL1/SCARB1/AGT/AKT1/APOE/ADGRB1/BMPR2/KRIT1/ALOX12/ANXA3/AAMP/CD40/APOH/RHOA/AGTR2/CEACAM1/CALR/RHOB/ANGPT2/ATP5B/ATP5A1/BMP4/ABL1/ANGPT1" 24 +"GO:0016054" "GO:0016054" "organic acid catabolic process" "33/743" "251/17381" 9.37592799671172e-09 1.9027618581562e-07 1.14175387369658e-07 "CDO1/BCAT1/KYAT1/ALDH7A1/AHCY/ACOX1/AKT2/ACAT1/ACAT2/AKT1/ATP2B4/AMT/AUH/ASPA/ABCD2/ACADM/ALDH3A2/ACADSB/BLMH/CBS/BCKDHA/ABAT/ACADVL/BCAT2/ACADL/ACACB/ACAA1/CD44/ACADS/ARG1/BCKDHB/ABCD1/AGXT" 33 +"GO:0046395" "GO:0046395" "carboxylic acid catabolic process" "33/743" "251/17381" 9.37592799671172e-09 1.9027618581562e-07 1.14175387369658e-07 "CDO1/BCAT1/KYAT1/ALDH7A1/AHCY/ACOX1/AKT2/ACAT1/ACAT2/AKT1/ATP2B4/AMT/AUH/ASPA/ABCD2/ACADM/ALDH3A2/ACADSB/BLMH/CBS/BCKDHA/ABAT/ACADVL/BCAT2/ACADL/ACACB/ACAA1/CD44/ACADS/ARG1/BCKDHB/ABCD1/AGXT" 33 +"GO:0048608" "GO:0048608" "reproductive structure development" "46/743" "429/17381" 9.45084194489251e-09 1.91047293221948e-07 1.14638091025629e-07 "ANXA1/BIRC2/CDKN1B/ADM/BRCA2/ATRX/AXL/BCL2L2/AKT1/ARRB1/ARNT/AR/NR0B1/BOK/CASP2/BSG/AFP/BMPR2/AMH/FOXL2/PRDM1/ANG/ASCL2/BAX/ADA/AMHR2/BMP7/ARRB2/CASP8/BCL2/BMPR1B/BIK/ATM/BMP6/CCNF/ZFP36L1/ADCYAP1/CDKN1C/BMP5/ACVR2A/BCL2L1/BMP4/CCND1/ALOX15B/CBL/BAK1" 46 +"GO:0008630" "GO:0008630" "intrinsic apoptotic signaling pathway in response to DNA damage" "20/743" "102/17381" 9.82803851640121e-09 1.97899219153215e-07 1.1874959501693e-07 "BCL2A1/BRCA2/BID/CASP9/CD74/CDKN2D/BCL2L2/BAD/BOK/CASP2/BAX/CDKN1A/BCL2/BCL3/ATM/BRCA1/CD44/BCL2L1/ABL1/BAK1" 20 +"GO:0086010" "GO:0086010" "membrane depolarization during action potential" "14/743" "49/17381" 1.0115354460419e-08 2.02895191211893e-07 1.21747432306145e-07 "CACNA1C/CAV3/CACNA1F/CACNA2D1/ATP1A2/CACNA1S/ANK3/CACNA1B/CACNA1D/HCN2/CACNA1E/ANK2/CACNB2/CACNA1A" 14 +"GO:0010517" "GO:0010517" "regulation of phospholipase activity" "15/743" "57/17381" 1.04370177429414e-08 2.08538868029813e-07 1.25133925387836e-07 "ANXA1/APOC2/ARF4/ABL2/AVPR1A/AGT/AVPR1B/ADRA1A/ANG/ADCYAP1R1/AGTR1/ARL1/BICD1/C5AR1/ABL1" 15 +"GO:0042100" "GO:0042100" "B cell proliferation" "19/743" "93/17381" 1.13046215294622e-08 2.25005447749873e-07 1.35014710574549e-07 "CD74/CD79A/BTK/CD81/PRDM1/BAX/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/ATM/BST1/AHR/CASP3/MS4A1/CD40LG/ABL1" 19 +"GO:0061458" "GO:0061458" "reproductive system development" "46/743" "432/17381" 1.17387500279581e-08 2.32751078140549e-07 1.39662482687947e-07 "ANXA1/BIRC2/CDKN1B/ADM/BRCA2/ATRX/AXL/BCL2L2/AKT1/ARRB1/ARNT/AR/NR0B1/BOK/CASP2/BSG/AFP/BMPR2/AMH/FOXL2/PRDM1/ANG/ASCL2/BAX/ADA/AMHR2/BMP7/ARRB2/CASP8/BCL2/BMPR1B/BIK/ATM/BMP6/CCNF/ZFP36L1/ADCYAP1/CDKN1C/BMP5/ACVR2A/BCL2L1/BMP4/CCND1/ALOX15B/CBL/BAK1" 46 +"GO:0006869" "GO:0006869" "lipid transport" "40/743" "347/17381" 1.19167422327112e-08 2.35378400970535e-07 1.41239009989948e-07 "ANXA1/BDKRB2/APOC2/ANXA2/APOC3/APOC4/SCARB1/AKT2/AGT/AKT1/ALB/ABCA2/VPS51/TSPO/APOE/APOA4/ACACA/ABCD2/ABCA1/CD36/APOA1/AGTR1/ABCA3/CAV1/AQP9/APOH/ACACB/APOA2/AGTR2/CEACAM1/ATM/BMP6/ABCA4/APOD/PLIN2/APOC1/APOB/APOF/ABCD1/SLC25A20" 40 +"GO:0050673" "GO:0050673" "epithelial cell proliferation" "41/743" "361/17381" 1.20031034101677e-08 2.36182738203871e-07 1.41721653231918e-07 "BMP2/CDKN1B/BRCA2/ACVRL1/SCARB1/CDK6/KLF9/BCL2L2/AKT1/BMPR1A/CDH3/APOE/ARNT/BAD/AR/CD34/AREG/ATP7A/BMPR2/KRIT1/ANG/CDC42/BAX/APOA1/CDKN2B/CAV1/APOH/CEACAM1/C5AR1/BMP6/CAV2/ZFP36L1/CDKN1C/BMP5/ACVR2A/RUNX3/CDH13/ARG1/ATP5A1/BMP4/CCND1" 41 +"GO:1902105" "GO:1902105" "regulation of leukocyte differentiation" "33/743" "254/17381" 1.26243276111296e-08 2.47465512831802e-07 1.48491891757705e-07 "ANXA1/AXL/CD4/CDK6/FAS/CD74/AGER/RUNX1/CD80/BTK/BAD/BGLAP/CD27/PRDM1/ADA/ATP6AP1/ZFP36L2/CASP8/BRAF/BCL6/CBFB/CD2/CEACAM1/ZFP36L1/CAMK4/C1QC/CA2/CD28/ADAM8/APCS/BMP4/CD86/ABL1" 33 +"GO:0050690" "GO:0050690" "regulation of defense response to virus by virus" "11/743" "29/17381" 1.38303553484903e-08 2.70083354446934e-07 1.62063746883998e-07 "AP2B1/AP1B1/CD4/CD8B/ARF1/CD247/AP1G1/AP2A1/AP2A2/CD28/B2M" 11 +"GO:0050670" "GO:0050670" "regulation of lymphocyte proliferation" "29/743" "206/17381" 1.59631532135808e-08 3.1056134541459e-07 1.86352599841961e-07 "ANXA1/AIF1/CD6/CD4/ARG2/CD74/AGER/CD80/BTK/CD81/CD3E/PRDM1/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/ATM/BST1/AHR/CASP3/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86" 29 +"GO:1905952" "GO:1905952" "regulation of lipid localization" "23/743" "137/17381" 1.75777685800036e-08 3.40692705623665e-07 2.04432948200317e-07 "APOC2/ANXA2/APOC3/APOC4/SCARB1/AKT2/AGT/AKT1/ABCA2/TSPO/APOE/APOA4/ABCA1/CD36/APOA1/AGTR1/C3/ACACB/APOA2/AGTR2/BMP6/APOC1/APOB" 23 +"GO:0032944" "GO:0032944" "regulation of mononuclear cell proliferation" "29/743" "207/17381" 1.78260567338772e-08 3.44215834320203e-07 2.0654700457556e-07 "ANXA1/AIF1/CD6/CD4/ARG2/CD74/AGER/CD80/BTK/CD81/CD3E/PRDM1/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/ATM/BST1/AHR/CASP3/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86" 29 +"GO:0016064" "GO:0016064" "immunoglobulin mediated immune response" "28/743" "195/17381" 1.81993625309533e-08 3.50117847946778e-07 2.10088512879328e-07 "C4BPA/C2/C8A/C8G/C1QA/C6/CD74/C1S/BTK/C5/CD27/C1R/C1QB/C8B/C7/CD40/BCL6/C4BPB/C3/C9/BCL3/C4B/C1QC/C4A/CD28/CD40LG/C1QBP/SERPING1" 28 +"GO:0044706" "GO:0044706" "multi-multicellular organism process" "30/743" "220/17381" 1.90525021720665e-08 3.65172958297941e-07 2.19122344668991e-07 "STS/ADM/AVPR1A/DDR1/AGT/CALCA/AKT1/ACVR1B/ADCY7/AR/BYSL/ADRA2B/BSG/AGRP/ADRA2C/BMPR2/PRDM1/BCL2/CD38/ACR/AKR1B1/CALR/ARNTL/AMBP/ADCYAP1/ANGPT2/ACVR2A/ARG1/ARHGDIB/C1QBP" 30 +"GO:0070661" "GO:0070661" "leukocyte proliferation" "35/743" "286/17381" 2.17134370152114e-08 4.14638511268337e-07 2.48804191862007e-07 "ANXA1/AIF1/CD6/CD4/ARG2/CD74/CD79A/AGER/CD80/BTK/CD81/CD3E/PRDM1/BAX/ADA/CDKN1A/CD151/BCL2/CD40/BCL6/CD38/ATM/CCND3/BST1/AHR/CASP3/MS4A1/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86/ABL1" 35 +"GO:1904646" "GO:1904646" "cellular response to amyloid-beta" "10/743" "24/17381" 2.18276940183091e-08 4.15287928473344e-07 2.49193875209024e-07 "APP/CASP4/ADRB2/ATP1A3/CD36/CACNA2D1/CACNB1/PARP1/CDK5/CACNA1A" 10 +"GO:0009206" "GO:0009206" "purine ribonucleoside triphosphate biosynthetic process" "15/743" "60/17381" 2.23314868055489e-08 4.23316645489801e-07 2.54011513693346e-07 "ATP5F1/ALDOA/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/PARP1/ATP5G2/ATP5B/ATP5A1" 15 +"GO:0010817" "GO:0010817" "regulation of hormone levels" "49/743" "486/17381" 2.28040368404043e-08 4.30696681201066e-07 2.58439910407962e-07 "ANXA1/BMP2/SLC25A6/ADM/ACVR2B/CACNA1C/SCARB1/AGT/TSPO/ALDH9A1/BTK/ARRB1/ARNT/ADCY5/BAD/SLC25A5/ATP1A1/ADRA2B/CCKAR/ASMT/BLK/ADRA2C/CASR/AFP/FOXL2/ARL2/AGTR1/ADRA2A/ADH7/CAMK2G/ABAT/BCAT2/ADH4/ALDH1A1/CD38/CACNA1D/ALDH1A3/AKR1B1/AGTR2/AQP1/ARNTL/BMP6/ADCYAP1/BMP5/CACNA1E/AANAT/CACNA1A/SLC25A4/ADORA1" 49 +"GO:1904031" "GO:1904031" "positive regulation of cyclin-dependent protein kinase activity" "12/743" "37/17381" 2.35734112827709e-08 4.43608739593961e-07 2.66187802044685e-07 "CCNC/CDKN1B/CCNH/CCNB1/AKT1/CCND2/CCNT1/CDC6/CDKN1A/CCNT2/CCND3/CCND1" 12 +"GO:0006957" "GO:0006957" "complement activation, alternative pathway" "8/743" "14/17381" 2.56669811201535e-08 4.81255896002877e-07 2.88778010314465e-07 "CFB/C8A/C8G/C5/C8B/C7/C3/C9" 8 +"GO:0060048" "GO:0060048" "cardiac muscle contraction" "22/743" "129/17381" 2.66957822770826e-08 4.9873889272167e-07 2.99268697387018e-07 "CALM1/CACNA1C/CALM3/ATP2A2/ADRA1A/ATP1A3/ATP1A1/CAMK2D/CAV3/CALM2/CACNA2D1/ADRA1B/ATP1A2/CAV1/CACNA1D/ACTC1/ATP1B1/CASQ2/GRK2/ANK2/CACNB2/ADORA1" 22 +"GO:0032025" "GO:0032025" "response to cobalt ion" "7/743" "10/17381" 2.72025854608634e-08 5.02762070571315e-07 3.01682808682508e-07 "ATF1/CASP9/ATP7A/ALAD/CASP8/CASP3/BNIP3" 7 +"GO:0034378" "GO:0034378" "chylomicron assembly" "7/743" "10/17381" 2.72025854608634e-08 5.02762070571315e-07 3.01682808682508e-07 "APOC2/APOC3/APOE/APOA4/APOA1/APOA2/APOB" 7 +"GO:0071436" "GO:0071436" "sodium ion export" "7/743" "10/17381" 2.72025854608634e-08 5.02762070571315e-07 3.01682808682508e-07 "ATP1B3/ATP1A3/ATP1B2/ATP1A1/FXYD2/ATP1A2/ATP1B1" 7 +"GO:0070997" "GO:0070997" "neuron death" "37/743" "316/17381" 2.80085085882191e-08 5.15815060299052e-07 3.09515266286744e-07 "AARS/APP/BID/AXL/CASP9/AKT2/FAS/AKT1/APOE/BAD/CD34/BOK/CASP2/ASCL1/CDC34/CDC42/BAX/BDNF/ADARB1/FASLG/CASP8/BCL2/BRAF/ATM/PARP1/C5AR1/ADORA2A/CASP3/CDK5/APAF1/ADAM8/BCL2L1/BNIP3/ATF4/ABL1/CBL/ANGPT1" 37 +"GO:0097194" "GO:0097194" "execution phase of apoptosis" "17/743" "79/17381" 2.94811668089798e-08 5.41010773888193e-07 3.24633975686788e-07 "BIRC2/CASP9/AKT1/BOK/APC/CASP2/FOXL2/BAX/CASP10/CASP8/CASP6/BMX/CASP7/CASP3/APAF1/BCL2L1/BNIP1" 17 +"GO:0051592" "GO:0051592" "response to calcium ion" "21/743" "119/17381" 2.97505919876078e-08 5.44025842882934e-07 3.26443170405218e-07 "CALM1/CALM3/ADCY1/BAD/ANXA7/ADD1/CAMK2D/ENTPD6/CALM2/CASR/CAPN3/ALOX15/CAV1/AQP3/BRAF/CASQ2/APOBEC1/ALOX5AP/AANAT/CCND1/ANXA11" 21 +"GO:0050867" "GO:0050867" "positive regulation of cell activation" "40/743" "359/17381" 3.0927046578882e-08 5.63547415653924e-07 3.38157106774285e-07 "ANXA1/APP/AIF1/CD6/AXL/CD3G/CD4/CD74/AKT1/CD47/AGER/CD80/BTK/CD81/BAD/CD247/CD3E/AP1G1/CD27/CD3D/CAPN3/PRDM1/CDC42/ADA/CDKN1A/ADORA2B/CAV1/BCL2/CD40/BCL6/CD38/CD2/BST1/CD5/CD59/CD28/ADAM8/CD1D/CD40LG/CD86" 40 +"GO:1901615" "GO:1901615" "organic hydroxy compound metabolic process" "49/743" "492/17381" 3.36571398177764e-08 6.11142801954362e-07 3.66716758864046e-07 "APP/BMP2/CALM1/SCARB1/BAAT/ACAT2/ALDH1B1/CDH3/APOE/ADH1B/APOA4/ACACA/ACLY/ADH1A/ABCA1/ATP7A/ALDH3A2/ACTN3/ADCYAP1R1/APOA1/CAT/ALOX12/ADH7/ADH5/ALOX15/ADH6/BCL2/ABAT/ACADVL/ADH4/ALDH3B1/ALDH1A1/ACADL/ALDH3B2/ALDH1A3/ACACB/AKR1B1/APOA2/AGTR2/ACAA1/BMP6/AOC2/BMP5/APOC1/ALDH2/ADH1C/APOB/APOF/ASIP" 49 +"GO:0002791" "GO:0002791" "regulation of peptide secretion" "46/743" "448/17381" 3.58040091026919e-08 6.47852262609897e-07 3.88744301998311e-07 "ANXA1/SLC25A6/CASP1/CACNA1C/ANXA4/ARG2/CD74/ARRB1/ARF1/ADCY5/BAD/SLC25A5/CASP5/CD34/C5/BLK/ADRA2C/CASR/ANG/ARL2/APOA1/ACHE/ADRA2A/ABAT/CD40/CD38/CACNA1D/APBB1/APOA2/CD2/AGTR2/CD14/ARNTL/BMP6/ADCYAP1/ADORA2A/CACNA1E/CD58/ADAM8/CD40LG/CACNA1A/SLC25A4/ABL1/ALOX15B/ANGPT1/ADORA1" 46 +"GO:0002237" "GO:0002237" "response to molecule of bacterial origin" "38/743" "333/17381" 3.63609917106314e-08 6.53962194634803e-07 3.92410571914095e-07 "ALPL/CASP1/ADM/CD6/AXL/BDKRB1/CDK4/SCARB1/CASP9/FAS/AKT1/ACP5/TSPO/CD80/ABR/BCR/ATP4B/CD27/ABCA1/CD36/PRDM1/ALAD/FASLG/ADH5/TNFRSF8/CASP8/CD40/RHOA/CD14/C5AR1/BMP6/C4B/CASP3/ARG1/APOB/CD86/ABL1/B2M" 38 +"GO:0002696" "GO:0002696" "positive regulation of leukocyte activation" "39/743" "347/17381" 3.63944177883717e-08 6.53962194634803e-07 3.92410571914095e-07 "ANXA1/APP/AIF1/CD6/AXL/CD3G/CD4/CD74/AKT1/CD47/AGER/CD80/BTK/CD81/BAD/CD247/CD3E/AP1G1/CD27/CD3D/PRDM1/CDC42/ADA/CDKN1A/ADORA2B/CAV1/BCL2/CD40/BCL6/CD38/CD2/BST1/CD5/CD59/CD28/ADAM8/CD1D/CD40LG/CD86" 39 +"GO:0007596" "GO:0007596" "blood coagulation" "39/743" "348/17381" 3.93561503732936e-08 7.04733834539081e-07 4.22876137684269e-07 "ANXA2/AXL/AKT1/ASIC2/APOE/ARRB1/CD34/ADRA2B/CD9/SERPINC1/ADRA2C/CAPZB/CD36/A2M/CDC42/ACTB/ALOX12/RHOG/ADRA2A/ACTG1/ARRB2/CAV1/ABAT/CD40/CAPZA2/C4BPB/APOH/CAPZA1/RHOA/CEACAM1/ENTPD2/RHOB/ENTPD1/ADORA2A/ANXA5/CD59/CD40LG/C1QBP/SERPING1" 39 +"GO:0046890" "GO:0046890" "regulation of lipid biosynthetic process" "25/743" "167/17381" 4.55639307526443e-08 8.12346977209393e-07 4.87449495604925e-07 "ANXA1/BMP2/APOC2/APOC3/AVPR1A/CDK4/SCARB1/AKT1/TSPO/APOE/APOA4/ACACA/ATP1A1/APOA1/ACADVL/ACADL/C3/ACACB/CEACAM1/BMP6/BMP5/BRCA1/AVP/APOC1/APOB" 25 +"GO:0007007" "GO:0007007" "inner mitochondrial membrane organization" "12/743" "39/17381" 4.59937515598748e-08 8.12346977209393e-07 4.87449495604925e-07 "ATP5F1/ATP5C1/ATP5G1/ATP5E/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/ATP5G2/ATP5B/ATP5A1" 12 +"GO:0015682" "GO:0015682" "ferric iron transport" "12/743" "39/17381" 4.59937515598748e-08 8.12346977209393e-07 4.87449495604925e-07 "ATP6V1C1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/ATP6AP1/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1/ARHGAP1/B2M" 12 +"GO:0072512" "GO:0072512" "trivalent inorganic cation transport" "12/743" "39/17381" 4.59937515598748e-08 8.12346977209393e-07 4.87449495604925e-07 "ATP6V1C1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/ATP6AP1/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1/ARHGAP1/B2M" 12 +"GO:0045785" "GO:0045785" "positive regulation of cell adhesion" "42/743" "394/17381" 4.97000703047267e-08 8.74822666078097e-07 5.24938085925326e-07 "ANXA1/AIF1/CD6/CD3G/CD4/CDK6/CD74/AKT1/CD47/AZU1/AGER/CD80/BAD/CD247/CD3E/CD27/CD36/CD3D/CDC42/ARL2/APOA1/ALOX12/ADA/BMP7/ALOX15/CAV1/BRAF/ANK3/BCL6/CALR/CD5/CDH13/CD59/CD44/CD28/ADAM8/CD1D/CD40LG/C1QBP/CD86/ABL1/ANGPT1" 42 +"GO:0001819" "GO:0001819" "positive regulation of cytokine production" "43/743" "409/17381" 5.12555239926393e-08 8.98015186448105e-07 5.38854777527975e-07 "ANXA1/BIRC2/CASP1/CD6/CD4/POLR3D/CD74/AGT/AZU1/AGER/C3AR1/RUNX1/CD80/ARNT/CASP5/CD34/CD3E/C5/CD36/ADRA2A/TNFRSF8/ADORA2B/CD40/C3/BCL3/APOA2/CD2/AGTR2/CD14/BIRC3/C5AR1/ADCYAP1/BRCA1/CD58/CD28/ADAM8/CD40LG/ATF4/C1QBP/CD86/ABL1/ALOX15B/B2M" 43 +"GO:0010876" "GO:0010876" "lipid localization" "41/743" "380/17381" 5.13647333697853e-08 8.98015186448105e-07 5.38854777527975e-07 "ANXA1/BDKRB2/APOC2/ANXA2/APOC3/APOC4/SCARB1/AKT2/AGT/AKT1/ALB/ABCA2/VPS51/TSPO/APOE/APOA4/ACACA/ABCD2/ABCA1/CD36/APOA1/AGTR1/ABCA3/CAV1/AQP9/C3/APOH/ACACB/APOA2/AGTR2/CEACAM1/ATM/BMP6/ABCA4/APOD/PLIN2/APOC1/APOB/APOF/ABCD1/SLC25A20" 41 +"GO:0070663" "GO:0070663" "regulation of leukocyte proliferation" "29/743" "217/17381" 5.1559034540993e-08 8.98377117002151e-07 5.39071954265211e-07 "ANXA1/AIF1/CD6/CD4/ARG2/CD74/AGER/CD80/BTK/CD81/CD3E/PRDM1/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/ATM/BST1/AHR/CASP3/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86" 29 +"GO:0042770" "GO:0042770" "signal transduction in response to DNA damage" "21/743" "123/17381" 5.40932294604096e-08 9.39370679387985e-07 5.63670176291799e-07 "CDKN1B/ATR/CDC25C/BRCA2/BID/ATRX/CDK1/CASP9/CD74/CCNB1/CDC5L/CASP2/BAX/CDK2/CDKN1A/BCL3/ATM/BRCA1/CD44/PTTG1IP/ABL1" 21 +"GO:0042044" "GO:0042044" "fluid transport" "10/743" "26/17381" 5.46866964133175e-08 9.4650051484588e-07 5.67948440131268e-07 "AQP6/AQP2/AQP8/AQP7/AQP4/AQP3/AQP9/AQP1/AVP/AQP5" 10 +"GO:1904427" "GO:1904427" "positive regulation of calcium ion transmembrane transport" "15/743" "64/17381" 5.70988027841843e-08 9.81825402540491e-07 5.89145169080996e-07 "CASQ1/CALM1/APLNR/BDKRB1/CALM3/CALM2/CAPN3/CACNA2D1/CALCR/BAX/CD19/ATP1B1/ANK2/CACNB2/ABL1" 15 +"GO:0097191" "GO:0097191" "extrinsic apoptotic signaling pathway" "29/743" "218/17381" 5.71071393554952e-08 9.81825402540491e-07 5.89145169080996e-07 "BCL2A1/BID/CASP9/FAS/AGT/BCL2L2/AKT1/ACVR1B/BAD/AR/BOK/CASP2/CD27/BAX/FASLG/CASP8/CAV1/BCL2/ATF3/BMPR1B/AGTR2/ACVR1/BMP5/CASP3/BRCA1/BCL2L1/BMP4/BAK1/CD70" 29 +"GO:0042113" "GO:0042113" "B cell activation" "33/743" "271/17381" 6.19057450044274e-08 1.0608020874103e-06 6.36535196106869e-07 "FAS/CD74/CD79A/CXCR5/BTK/CD81/BAD/CD27/PRDM1/BAX/ADA/CDKN1A/ZFP36L2/CD79B/CASP8/BCL2/CD40/BCL6/CD38/BCL3/ATM/BST1/BST2/ZFP36L1/AHR/CASP3/MS4A1/CD28/CD40LG/CDH17/CD86/ABL1/BAK1" 33 +"GO:0050817" "GO:0050817" "coagulation" "39/743" "354/17381" 6.2461772916573e-08 1.06679760674345e-06 6.4013281258951e-07 "ANXA2/AXL/AKT1/ASIC2/APOE/ARRB1/CD34/ADRA2B/CD9/SERPINC1/ADRA2C/CAPZB/CD36/A2M/CDC42/ACTB/ALOX12/RHOG/ADRA2A/ACTG1/ARRB2/CAV1/ABAT/CD40/CAPZA2/C4BPB/APOH/CAPZA1/RHOA/CEACAM1/ENTPD2/RHOB/ENTPD1/ADORA2A/ANXA5/CD59/CD40LG/C1QBP/SERPING1" 39 +"GO:0070169" "GO:0070169" "positive regulation of biomineral tissue development" "12/743" "40/17381" 6.31668611836e-08 1.07252155866199e-06 6.43567474813705e-07 "BMP2/ADRB2/ACVR2B/AMELX/BMPR1A/BMPR2/BMP7/BMPR1B/ACVR1/BMP6/ACVR2A/BMP4" 12 +"GO:0002683" "GO:0002683" "negative regulation of immune system process" "43/743" "412/17381" 6.32114155346681e-08 1.07252155866199e-06 6.43567474813705e-07 "ANXA1/C4BPA/AXL/BPI/CDK6/ARG2/FAS/CD74/BTK/ABR/BCR/C5/ADAR/A2M/PRDM1/APOA1/ADA/ALOX15/ARRB2/BCL6/C4BPB/APOA2/CEACAM1/ATM/CD14/BST2/AMBP/ZFP36L1/ADCYAP1/ADORA2A/BMP5/APOD/CASP3/C1QC/CD59/ARG1/APCS/BMP4/C1QBP/CD86/SERPING1/ANGPT1/ADORA1" 43 +"GO:0006885" "GO:0006885" "regulation of pH" "19/743" "103/17381" 6.46129089896316e-08 1.09271831379524e-06 6.55686554934342e-07 "ATP6V1C1/ATP12A/AVPR1A/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/FASLG/ATP6AP1/ATP6V1G2/ATP6V0C/BCL2/ATP6V0B/ATP1A4/ATP6V1E1/CA2/CA7/AVP/ATP5B" 19 +"GO:0034381" "GO:0034381" "plasma lipoprotein particle clearance" "14/743" "56/17381" 6.58393282739551e-08 1.10983232513915e-06 6.65955832018404e-07 "APOC2/ANXA2/AP2B1/APOC3/APOC4/SCARB1/APOE/CD36/APOA1/AP2A1/APOA2/AP2A2/APOC1/APOB" 14 +"GO:0010862" "GO:0010862" "positive regulation of pathway-restricted SMAD protein phosphorylation" "13/743" "48/17381" 6.91807276453968e-08 1.16237099209392e-06 6.97481703875327e-07 "BMP2/ACVRL1/BMPR1A/ACVR1B/BMP8B/BMPR2/BMP7/ACVR1/BMP6/BMP5/ACVR2A/BMP4/BMP3" 13 +"GO:0009201" "GO:0009201" "ribonucleoside triphosphate biosynthetic process" "15/743" "65/17381" 7.13291235679635e-08 1.19458969082269e-06 7.1681456149035e-07 "ATP5F1/ALDOA/ATP5C1/ATP5G1/ATP5E/ATP6V0A1/ATP5I/ATP5O/ATP5G3/ATP5D/ATP5J/PARP1/ATP5G2/ATP5B/ATP5A1" 15 +"GO:0010872" "GO:0010872" "regulation of cholesterol esterification" "7/743" "11/17381" 7.20389379868854e-08 1.20258549703914e-06 7.21612451821093e-07 "AGT/APOE/APOA4/APOA1/AGTR1/APOA2/APOC1" 7 +"GO:0045926" "GO:0045926" "negative regulation of growth" "30/743" "234/17381" 7.82395820984098e-08 1.30189658314878e-06 7.81204153631101e-07 "BBS2/CDKN1B/ADRB2/ACVRL1/BDKRB1/AGT/CDKN2D/APBB2/ACVR1B/CAV3/CDA/ADRB3/CD36/BMPR2/BTG1/ADRB1/CDKN1A/CAMP/ARHGAP4/BCL2/BCL6/OSGIN2/APBB1/AGTR2/BST2/CDK5/CDKN2A/BMP4/CDKN2C/ALOX15B" 30 +"GO:0072330" "GO:0072330" "monocarboxylic acid biosynthetic process" "27/743" "196/17381" 7.8805081379209e-08 1.30710351326092e-06 7.84328576479982e-07 "ANXA1/APOC2/APOC3/AVPR1A/BAAT/CD74/APOA4/ACACA/ACLY/BGN/APOA1/ALOX12/ALOX15/CBR1/ABAT/ACADVL/ACADL/ALDH1A3/ACACB/CEACAM1/ALOX12B/BRCA1/ASNS/AVP/APOC1/ALOX15B/AGXT" 27 +"GO:0051251" "GO:0051251" "positive regulation of lymphocyte activation" "36/743" "315/17381" 8.01696112929937e-08 1.32548798224039e-06 7.953601927504e-07 "ANXA1/AIF1/CD6/AXL/CD3G/CD4/CD74/AKT1/CD47/AGER/CD80/BTK/CD81/BAD/CD247/CD3E/AP1G1/CD27/CD3D/PRDM1/CDC42/ADA/CDKN1A/CAV1/BCL2/CD40/BCL6/CD38/BST1/CD5/CD59/CD28/ADAM8/CD1D/CD40LG/CD86" 36 +"GO:0043542" "GO:0043542" "endothelial cell migration" "26/743" "184/17381" 8.14913137794339e-08 1.34304951849863e-06 8.05898007540496e-07 "ACVRL1/SCARB1/AGT/AKT1/APOE/ADGRB1/BMPR2/KRIT1/APOA1/ALOX12/ANXA3/AAMP/CD40/APOH/RHOA/AGTR2/CEACAM1/CALR/RHOB/ANGPT2/ATP5B/CDH13/ATP5A1/BMP4/ABL1/ANGPT1" 26 +"GO:0006633" "GO:0006633" "fatty acid biosynthetic process" "21/743" "126/17381" 8.322959563785e-08 1.36734335690754e-06 8.20475545970451e-07 "ANXA1/APOC2/APOC3/AVPR1A/CD74/APOA4/ACACA/ACLY/APOA1/ALOX12/ALOX15/CBR1/ACADVL/ACADL/ACACB/CEACAM1/ALOX12B/BRCA1/AVP/APOC1/ALOX15B" 21 +"GO:0010882" "GO:0010882" "regulation of cardiac muscle contraction by calcium ion signaling" "10/743" "27/17381" 8.35392223704545e-08 1.36808694863007e-06 8.20921738816924e-07 "CALM1/CACNA1C/CALM3/ATP2A2/CAMK2D/CALM2/ATP1A2/ATP1B1/CASQ2/ANK2" 10 +"GO:0001836" "GO:0001836" "release of cytochrome c from mitochondria" "14/743" "57/17381" 8.38772898421922e-08 1.36929014174557e-06 8.21643715870719e-07 "BCL2A1/BID/AKT1/BAD/BOK/BAX/ARRB2/BCL2/CCK/BIK/AVP/BCL2L1/BNIP3/BAK1" 14 +"GO:0007162" "GO:0007162" "negative regulation of cell adhesion" "31/743" "248/17381" 8.5452696068792e-08 1.39062170489308e-06 8.34443738506907e-07 "ANXA1/BMP2/ACVRL1/ARG2/CD74/ARHGDIG/ARHGDIA/CD9/APOA1/ALOX12/ABAT/BCL6/RHOA/ASS1/CEACAM1/ARHGAP6/ADORA2A/ANGPT2/ACTN4/CDH1/APOD/CASP3/CDKN2A/ATP5B/CDH13/ARG1/ADAM10/BMP4/ARHGDIB/ABL1/ANGPT1" 31 +"GO:0042304" "GO:0042304" "regulation of fatty acid biosynthetic process" "12/743" "41/17381" 8.58553949037705e-08 1.39279519945772e-06 8.3574794577173e-07 "ANXA1/APOC2/APOC3/AVPR1A/APOA4/APOA1/ACADVL/ACADL/CEACAM1/BRCA1/AVP/APOC1" 12 +"GO:0032496" "GO:0032496" "response to lipopolysaccharide" "36/743" "316/17381" 8.68760387836076e-08 1.40494843970365e-06 8.43040507933034e-07 "ALPL/CASP1/ADM/CD6/AXL/BDKRB1/CDK4/SCARB1/CASP9/FAS/AKT1/ACP5/TSPO/CD80/ABR/BCR/ATP4B/CD27/ABCA1/CD36/PRDM1/ALAD/FASLG/ADH5/TNFRSF8/CASP8/CD40/RHOA/CD14/C5AR1/BMP6/CASP3/ARG1/APOB/CD86/ABL1" 36 +"GO:0032845" "GO:0032845" "negative regulation of homeostatic process" "27/743" "197/17381" 8.7696367494367e-08 1.41379657876433e-06 8.48349841312945e-07 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CALM3/CD74/CALCA/CAMK2D/CALM2/CAPN3/BAX/CD19/ADA/ADRA2A/ATP1A2/FASLG/BCL2/CD38/ATM/PARP1/CASQ2/ZFP36L1/ANK2/AVPR2/ABL1/ADORA1" 27 +"GO:0001503" "GO:0001503" "ossification" "40/743" "373/17381" 8.83277388442429e-08 1.41955294571105e-06 8.51803954202408e-07 "BMP2/ALPL/ADRB2/ACVR2B/AMELX/CDK6/CALCA/AKT1/BMPR1A/RUNX1/RUNX2/BGLAP/BMP8B/ADAR/AREG/ASGR2/CASR/BMPR2/ATP6V1B1/CAT/BMP1/ACHE/ATP6AP1/BMP7/ALOX15/CDH11/BCL2/BMPR1B/RHOA/CBFB/ACVR1/BMP6/BMP5/ACVR2A/RUNX3/ATP5B/AHSG/JAG1/BMP4/BMP3" 40 +"GO:0019217" "GO:0019217" "regulation of fatty acid metabolic process" "17/743" "85/17381" 9.26399860491964e-08 1.48424745450338e-06 8.90623949307901e-07 "ANXA1/APOC2/APOC3/AVPR1A/AKT2/AKT1/APOA4/ABCD2/APOA1/CAV1/ACADVL/ACADL/ACACB/CEACAM1/BRCA1/AVP/APOC1" 17 +"GO:0010039" "GO:0010039" "response to iron ion" "11/743" "34/17381" 9.40120605270808e-08 1.49696127146967e-06 8.98252886007735e-07 "C1QA/CCNB1/ACO1/ATP7A/ALAD/BCL2/ABAT/APBB1/BMP6/CCND1/B2M" 11 +"GO:0045737" "GO:0045737" "positive regulation of cyclin-dependent protein serine/threonine kinase activity" "11/743" "34/17381" 9.40120605270808e-08 1.49696127146967e-06 8.98252886007735e-07 "CCNC/CDKN1B/CCNH/CCNB1/AKT1/CCND2/CCNT1/CDC6/CCNT2/CCND3/CCND1" 11 +"GO:0003085" "GO:0003085" "negative regulation of systemic arterial blood pressure" "8/743" "16/17381" 1.01906508769802e-07 1.61768767755745e-06 9.70694868811486e-07 "ADRB2/CALCA/ADRA1A/ADRB3/BBS4/BMPR2/ADRB1/AGTR2" 8 +"GO:0034308" "GO:0034308" "primary alcohol metabolic process" "14/743" "58/17381" 1.06261342466007e-07 1.68165886012718e-06 1.009080831401e-06 "ALDH1B1/ADH1B/ADH1A/ALDH3A2/ADH7/ADH5/ADH6/ADH4/ALDH3B1/ALDH1A1/ALDH3B2/ALDH1A3/ALDH2/ADH1C" 14 +"GO:0050708" "GO:0050708" "regulation of protein secretion" "43/743" "421/17381" 1.16789255144373e-07 1.8426353517443e-06 1.10567491231033e-06 "ANXA1/SLC25A6/CASP1/CACNA1C/ANXA4/ARG2/ARRB1/ARF1/ADCY5/BAD/SLC25A5/CASP5/CD34/C5/BLK/ADRA2C/CASR/ANG/ARL2/APOA1/ACHE/ADRA2A/ABAT/CD40/CD38/CACNA1D/APBB1/APOA2/CD2/AGTR2/CD14/ARNTL/BMP6/ADORA2A/CACNA1E/CD58/ADAM8/CD40LG/CACNA1A/SLC25A4/ABL1/ALOX15B/ANGPT1" 43 +"GO:0002026" "GO:0002026" "regulation of the force of heart contraction" "10/743" "28/17381" 1.24989997459793e-07 1.96602807554537e-06 1.17971682132903e-06 "ADM/ATP2A2/ADRA1A/ATP2B4/ATP1A1/CAMK2D/ATP1A2/ADRB1/CAV1/GRK2" 10 +"GO:0055117" "GO:0055117" "regulation of cardiac muscle contraction" "16/743" "77/17381" 1.26210272832641e-07 1.97920655123914e-06 1.18762457689407e-06 "CALM1/CACNA1C/CALM3/ATP2A2/ADRA1A/ATP1A1/CAMK2D/CAV3/CALM2/ADRA1B/ATP1A2/CAV1/ATP1B1/CASQ2/ANK2/ADORA1" 16 +"GO:0050678" "GO:0050678" "regulation of epithelial cell proliferation" "35/743" "307/17381" 1.28958820808929e-07 2.01619908666529e-06 1.20982197928555e-06 "BMP2/CDKN1B/BRCA2/ACVRL1/CDK6/KLF9/AKT1/BMPR1A/CDH3/APOE/ARNT/BAD/AR/ATP7A/BMPR2/KRIT1/ANG/CDC42/BAX/CDKN2B/CAV1/APOH/CEACAM1/C5AR1/BMP6/CAV2/ZFP36L1/CDKN1C/BMP5/RUNX3/CDH13/ARG1/ATP5A1/BMP4/CCND1" 35 +"GO:0006730" "GO:0006730" "one-carbon metabolic process" "11/743" "35/17381" 1.31834677166029e-07 2.04878214514775e-06 1.22937347128113e-06 "AHCY/CA9/CA6/CA8/CA3/CA4/CA12/CA2/CA7/CA1/CA5A" 11 +"GO:0030501" "GO:0030501" "positive regulation of bone mineralization" "11/743" "35/17381" 1.31834677166029e-07 2.04878214514775e-06 1.22937347128113e-06 "BMP2/ADRB2/ACVR2B/BMPR1A/BMPR2/BMP7/BMPR1B/ACVR1/BMP6/ACVR2A/BMP4" 11 +"GO:0033077" "GO:0033077" "T cell differentiation in thymus" "15/743" "68/17381" 1.35409927644595e-07 2.09178022555456e-06 1.25517450605359e-06 "CDK6/FAS/CD74/CD3E/AIRE/CD3D/ADA/ZFP36L2/BCL2/ZFP36L1/CAMK4/CD28/ADAM8/BMP4/B2M" 15 +"GO:0050764" "GO:0050764" "regulation of phagocytosis" "15/743" "68/17381" 1.35409927644595e-07 2.09178022555456e-06 1.25517450605359e-06 "C4BPA/C2/SCARB1/CD47/AZU1/ABR/BCR/CD36/ALOX15/C4BPB/C3/CALR/C4B/C4A/AHSG" 15 +"GO:0071260" "GO:0071260" "cellular response to mechanical stimulus" "16/743" "78/17381" 1.52565736520971e-07 2.34978478123816e-06 1.40999035945133e-06 "CASP1/FAS/AGT/AKT1/BAD/CASP5/ATP1A1/CASP2/ATP1A2/TNFRSF8/CASP8/CD40/AQP1/BMP6/BNIP3/BAK1" 16 +"GO:0007565" "GO:0007565" "female pregnancy" "26/743" "190/17381" 1.56551391047319e-07 2.40401616815986e-06 1.4425319493662e-06 "STS/ADM/DDR1/AGT/CALCA/AKT1/ACVR1B/ADCY7/AR/BYSL/ADRA2B/BSG/AGRP/ADRA2C/BMPR2/PRDM1/BCL2/CD38/AKR1B1/CALR/AMBP/ADCYAP1/ANGPT2/ARG1/ARHGDIB/C1QBP" 26 +"GO:0031623" "GO:0031623" "receptor internalization" "17/743" "88/17381" 1.57741531955672e-07 2.41512552624439e-06 1.44919812914741e-06 "AP2B1/ADM/ARRB1/CD81/ARF1/CD9/CAV3/CD36/CALCR/ACHE/ARRB2/CAV1/CD63/CEACAM1/GRK3/GRK2/ANGPT1" 17 +"GO:0010649" "GO:0010649" "regulation of cell communication by electrical coupling" "7/743" "12/17381" 1.66499349812981e-07 2.5416936144017e-06 1.52514541825274e-06 "CALM1/CALM3/CAMK2D/CALM2/CAV1/ANK3/CASQ2" 7 +"GO:0030888" "GO:0030888" "regulation of B cell proliferation" "14/743" "60/17381" 1.67852748641698e-07 2.54608936912452e-06 1.52778309461833e-06 "CD74/BTK/CD81/PRDM1/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/ATM/BST1/AHR/CASP3" 14 +"GO:0060393" "GO:0060393" "regulation of pathway-restricted SMAD protein phosphorylation" "14/743" "60/17381" 1.67852748641698e-07 2.54608936912452e-06 1.52778309461833e-06 "BMP2/ACVRL1/BMPR1A/ACVR1B/BMP8B/BMPR2/BMP7/ACVR1/BMP6/BMP5/ACVR2A/LDLRAD4/BMP4/BMP3" 14 +"GO:0090130" "GO:0090130" "tissue migration" "32/743" "269/17381" 1.68752821612422e-07 2.54608936912452e-06 1.52778309461833e-06 "ACVRL1/SCARB1/AGT/AKT1/ACTA2/ACTA1/APOE/ADGRB1/BMPR2/KRIT1/APOA1/ALOX12/ANXA3/AAMP/CD40/ACTG2/APOH/ACTC1/RHOA/AGTR2/CEACAM1/CALR/AQP1/ARSB/RHOB/ANGPT2/ATP5B/CDH13/ATP5A1/BMP4/ABL1/ANGPT1" 32 +"GO:0042476" "GO:0042476" "odontogenesis" "20/743" "120/17381" 1.68755295383519e-07 2.54608936912452e-06 1.52778309461833e-06 "BMP2/ALPL/AQP6/ADM/ACVR2B/AMELX/BMPR1A/RUNX2/CD34/BGLAP/BSG/BAX/BMP7/AQP3/AQP1/CA2/AMBN/AQP5/BMP4/AMELY" 20 +"GO:0030856" "GO:0030856" "regulation of epithelial cell differentiation" "22/743" "143/17381" 1.78170094007462e-07 2.68032045490877e-06 1.60832857197679e-06 "CDKN1B/ACVRL1/RUNX1/BAD/ADD1/ASCL1/CDH5/BTG1/ALOX12/CAV1/AQP3/ATOH1/CBFB/CEACAM1/ARNTL/BMP6/ZFP36L1/CDKN1C/JAG1/BMP4/CCND1/ALOX15B" 22 +"GO:0032409" "GO:0032409" "regulation of transporter activity" "30/743" "243/17381" 1.8165581621347e-07 2.72483724320205e-06 1.63504090871011e-06 "APP/CASQ1/ANXA2/CALM1/CACNB4/ADRB2/CALM3/ATP1B3/ACTN2/ATP1B2/CAMK2D/CAV3/CALM2/ATP7A/CACNA2D1/FXYD2/ADRA2A/ATP1A2/CAV1/BCL2/ANK3/CACNA1D/ATP1B1/CACNB1/APOA2/CASQ2/ACTN4/ANK2/CACNB2/CACNB3" 30 +"GO:0033572" "GO:0033572" "transferrin transport" "11/743" "36/17381" 1.82551783932734e-07 2.73036266431184e-06 1.6383564423534e-06 "ATP6V1C1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/ATP6AP1/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1/ARHGAP1" 11 +"GO:0034199" "GO:0034199" "activation of protein kinase A activity" "8/743" "17/17381" 1.85277191942886e-07 2.75000686879362e-06 1.65014396398498e-06 "ADCY1/ADCY6/ADCY5/ADCY9/ADCY7/ADCY8/ADCY3/ADCY2" 8 +"GO:0019722" "GO:0019722" "calcium-mediated signaling" "24/743" "167/17381" 1.85459400426855e-07 2.75000686879362e-06 1.65014396398498e-06 "CASQ1/CALM1/CACNA1C/AVPR1A/CD4/CALM3/AZU1/ATP2A2/BTK/ATP2B4/CD3E/CAMK2D/ADGRB2/CALM2/ACTN3/AGTR1/ADA/CD8A/ATP1A2/ATP1B1/BST1/CASQ2/ANK2/CDH13" 24 +"GO:0043112" "GO:0043112" "receptor metabolic process" "24/743" "167/17381" 1.85459400426855e-07 2.75000686879362e-06 1.65014396398498e-06 "ANXA2/AP2B1/ADM/APOE/ARRB1/CD81/ARF1/CAMLG/CD9/CAV3/CD36/CALCR/ACHE/CAPN1/ARRB2/CAV1/AP2A1/CD63/CEACAM1/GRK3/GRK2/CDK5/AP2A2/ANGPT1" 24 +"GO:0050777" "GO:0050777" "negative regulation of immune response" "21/743" "132/17381" 1.88987906156908e-07 2.79432118389143e-06 1.6767348065049e-06 "ANXA1/C4BPA/ARG2/ABR/BCR/ADAR/A2M/APOA1/ALOX15/ARRB2/BCL6/C4BPB/APOA2/CEACAM1/BST2/AMBP/ADCYAP1/CD59/ARG1/SERPING1/ANGPT1" 21 +"GO:0070265" "GO:0070265" "necrotic cell death" "13/743" "52/17381" 1.943848175079e-07 2.86593000171904e-06 1.71970373863639e-06 "BIRC2/CASP1/FAS/TSPO/BOK/BAX/FASLG/CASP8/CAV1/CD14/BIRC3/BNIP3/SLC25A4" 13 +"GO:0060249" "GO:0060249" "anatomical structure homeostasis" "40/743" "385/17381" 2.06484159440873e-07 3.03566910541625e-06 1.82155583238809e-06 "BBS2/ALDOA/ATR/BRCA2/ATRX/ADRB2/CALB1/CALCA/ALB/ACP5/CDH3/CD34/BGLAP/ACACA/SERPINA3/ADD1/CAV3/BBS4/CAPN3/CD7/BAX/ACTB/BBS1/ATP6AP1/ACTG1/CCNE1/CCT6A/AZGP1/BCL2/BARD1/CD38/BLM/AKR1B1/ATM/PARP1/ABCA4/CA2/APEX1/ADAM8/B2M" 40 +"GO:0045619" "GO:0045619" "regulation of lymphocyte differentiation" "23/743" "156/17381" 2.07990931714127e-07 3.04915884311787e-06 1.82965036098606e-06 "ANXA1/AXL/FAS/CD74/RUNX1/CD80/BTK/BAD/CD27/PRDM1/ADA/ZFP36L2/BRAF/BCL6/CBFB/CD2/ZFP36L1/CAMK4/CD28/ADAM8/BMP4/CD86/ABL1" 23 +"GO:0034440" "GO:0034440" "lipid oxidation" "18/743" "100/17381" 2.1074900838963e-07 3.08086474128908e-06 1.84867551218974e-06 "ACOX1/AKT2/ACAT1/ACAT2/AKT1/AUH/ABCD2/ACADM/ALDH3A2/ALOX12/ADH7/ACADVL/ACADL/ACACB/ACAA1/APOD/ACADS/ABCD1" 18 +"GO:0086012" "GO:0086012" "membrane depolarization during cardiac muscle cell action potential" "9/743" "23/17381" 2.16354557925168e-07 3.15390095003589e-06 1.8925009514581e-06 "CACNA1C/CAV3/CACNA2D1/ATP1A2/ANK3/CACNA1D/HCN2/ANK2/CACNB2" 9 +"GO:0009063" "GO:0009063" "cellular amino acid catabolic process" "19/743" "112/17381" 2.57117726451861e-07 3.73759616401231e-06 2.24274776177703e-06 "CDO1/BCAT1/KYAT1/ALDH7A1/AHCY/ACAT1/ATP2B4/AMT/AUH/ASPA/ACADSB/BLMH/CBS/BCKDHA/ABAT/BCAT2/ARG1/BCKDHB/AGXT" 19 +"GO:0033273" "GO:0033273" "response to vitamin" "17/743" "91/17381" 2.6218294744767e-07 3.80055112896833e-06 2.28052394212186e-06 "ALPL/CD4/CDKN2D/BCHE/ATP2B1/TSPO/BGLAP/ASCL1/CASR/ALAD/CAT/ADA/BMP7/AQP3/CD40/ARG1/CCND1" 17 +"GO:0044242" "GO:0044242" "cellular lipid catabolic process" "26/743" "195/17381" 2.6364161555739e-07 3.81102056008239e-06 2.28680613317936e-06 "APOC2/APOC3/SCARB1/ACOX1/AKT2/ACAT1/ACAT2/AKT1/APOE/APOA4/AUH/ABCD2/ACADM/AADAC/ALDH3A2/APOA1/ACADVL/ACADL/ACACB/APOA2/ACAA1/APOC1/DAGLA/ACADS/APOB/ABCD1" 26 +"GO:0001894" "GO:0001894" "tissue homeostasis" "27/743" "208/17381" 2.7011179496272e-07 3.89367281039575e-06 2.33640168638036e-06 "BBS2/ADRB2/CALCA/ALB/ACP5/CDH3/CD34/BGLAP/ACACA/SERPINA3/ADD1/BBS4/CD7/BAX/ACTB/BBS1/ATP6AP1/ACTG1/AZGP1/BCL2/BARD1/CD38/AKR1B1/ABCA4/CA2/ADAM8/B2M" 27 +"GO:0002455" "GO:0002455" "humoral immune response mediated by circulating immunoglobulin" "21/743" "135/17381" 2.79286994225959e-07 4.01475054199816e-06 2.40905448235842e-06 "C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C5/C1R/C1QB/C8B/C7/C4BPB/C3/C9/BCL3/C4B/C1QC/C4A/C1QBP/SERPING1" 21 +"GO:0006958" "GO:0006958" "complement activation, classical pathway" "20/743" "124/17381" 2.9313462215182e-07 4.20213758901847e-06 2.52149623953308e-06 "C4BPA/C2/C8A/C8G/C1QA/C6/C1S/C5/C1R/C1QB/C8B/C7/C4BPB/C3/C9/C4B/C1QC/C4A/C1QBP/SERPING1" 20 +"GO:0050671" "GO:0050671" "positive regulation of lymphocyte proliferation" "21/743" "136/17381" 3.17251558207492e-07 4.53529506553528e-06 2.72140766708957e-06 "ANXA1/AIF1/CD6/CD4/CD74/AGER/CD80/CD81/CD3E/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/BST1/CD59/CD28/CD1D/CD40LG/CD86" 21 +"GO:0060389" "GO:0060389" "pathway-restricted SMAD protein phosphorylation" "14/743" "63/17381" 3.211875212906e-07 4.57891301013459e-06 2.74758065189871e-06 "BMP2/ACVRL1/BMPR1A/ACVR1B/BMP8B/BMPR2/BMP7/ACVR1/BMP6/BMP5/ACVR2A/LDLRAD4/BMP4/BMP3" 14 +"GO:0009314" "GO:0009314" "response to radiation" "43/743" "437/17381" 3.29759531379852e-07 4.6882021288207e-06 2.81315968065519e-06 "ANXA1/APP/CALM1/ATR/BRCA2/CASP9/AKT2/CDKN2D/AKT1/ASIC2/CCND2/ARRB1/ATP1A3/AGRP/CACNA1F/OPN1SW/ALAD/BAX/CAT/ATP1A2/CDKN1A/BCL2/BRAF/BLM/BCL3/ATM/AQP1/RHOB/PARP1/ABCA4/ANGPT2/APOBEC1/CASP3/BRCA1/CDK5/ASNS/CDC25A/AANAT/BCL2L1/CCND1/ATF4/CBL/BAK1" 43 +"GO:0008637" "GO:0008637" "apoptotic mitochondrial changes" "20/743" "125/17381" 3.35215489038935e-07 4.75271275555202e-06 2.85186933717334e-06 "BNIP3L/BCL2A1/BID/AKT1/BAD/SLC25A5/BOK/BAX/ARRB2/CASP8/BCL2/CCK/ATP2A1/BIK/AVP/BCL2L1/BNIP3/CAMK2A/SLC25A4/BAK1" 20 +"GO:0070296" "GO:0070296" "sarcoplasmic reticulum calcium ion transport" "11/743" "38/17381" 3.38093018711682e-07 4.77442762929171e-06 2.86489936565686e-06 "CASQ1/CALM1/CACNA1C/CACNG1/CALM3/ATP2A2/CAMK2D/CALM2/ATP1A2/CASQ2/ANK2" 11 +"GO:0010951" "GO:0010951" "negative regulation of endopeptidase activity" "30/743" "250/17381" 3.38592258927547e-07 4.77442762929171e-06 2.86489936565686e-06 "APP/BIRC2/AGT/CDKN2D/AKT1/SERPINH1/ARRB1/SERPINA3/SERPINC1/CAST/C5/CD27/A2M/SERPINA6/ARRB2/XIAP/APLP2/C3/AQP1/BST2/BIRC3/AMBP/ADORA2A/C4B/BIRC5/AVP/C4A/CD44/AHSG/SERPING1" 30 +"GO:0086009" "GO:0086009" "membrane repolarization" "12/743" "46/17381" 3.4737987135464e-07 4.85911208773891e-06 2.91571434707954e-06 "ATP1B3/ATP1B2/ATP1A1/CAV3/CACNA2D1/ATP1A2/CAV1/CACNA1D/ATP1B1/CASQ2/ANK2/CACNB3" 12 +"GO:0001973" "GO:0001973" "adenosine receptor signaling pathway" "7/743" "13/17381" 3.47414777287613e-07 4.85911208773891e-06 2.91571434707954e-06 "ADCY5/ADORA3/ADA/ACPP/ADORA2B/ADORA2A/ADORA1" 7 +"GO:0034370" "GO:0034370" "triglyceride-rich lipoprotein particle remodeling" "7/743" "13/17381" 3.47414777287613e-07 4.85911208773891e-06 2.91571434707954e-06 "APOC2/APOC3/APOE/APOA4/APOA1/APOA2/APOB" 7 +"GO:0032946" "GO:0032946" "positive regulation of mononuclear cell proliferation" "21/743" "137/17381" 3.59898219773908e-07 5.02014363161718e-06 3.01234146214507e-06 "ANXA1/AIF1/CD6/CD4/CD74/AGER/CD80/CD81/CD3E/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/BST1/CD59/CD28/CD1D/CD40LG/CD86" 21 +"GO:0007050" "GO:0007050" "cell cycle arrest" "30/743" "251/17381" 3.69276315902476e-07 5.13711003977235e-06 3.08252725498672e-06 "CDKN1B/CDC25C/CDK1/CDK4/CDK6/AKT2/CDKN2D/APBB2/CCNB1/BIN1/CDK7/APC/CASP2/CDK9/BAX/CDK2/CDKN2B/CDKN1A/BARD1/APBB1/ATM/CALR/CDKN1C/BRCA1/CDK5/CDKN2A/CDKN3/CCND1/CDKN2C/ABL1" 30 +"GO:0051346" "GO:0051346" "negative regulation of hydrolase activity" "42/743" "424/17381" 3.7811405092107e-07 5.24595231505774e-06 3.14783815497998e-06 "ANXA1/APP/BIRC2/APOC3/AGT/CDKN2D/RHOH/AKT1/SERPINH1/ARRB1/SERPINA3/SERPINC1/CAST/C5/CD27/BBS4/A2M/ARL2/APOA1/SERPINA6/ARRB2/XIAP/APLP2/C3/BICD1/APOA2/AQP1/BST2/BIRC3/AMBP/ADCYAP1/ADORA2A/C4B/BIRC5/AVP/APOC1/C4A/CD44/AHSG/APCS/SERPING1/ABL1" 42 +"GO:0031099" "GO:0031099" "regeneration" "25/743" "186/17381" 3.82633196300382e-07 5.29445666003871e-06 3.17694322850022e-06 "ANXA1/ADM/AXL/CDK1/CDK4/BAAT/CCNB1/TSPO/APOE/APOA4/BCL9/CAPN3/ATIC/APOA1/ANXA3/CDKN1A/BCL2/BRAF/APOA2/C5AR1/ANGPT2/APOD/CCNA2/CCND1/BAK1" 25 +"GO:0006940" "GO:0006940" "regulation of smooth muscle contraction" "14/743" "64/17381" 3.95132362472393e-07 5.45282660211903e-06 3.27197324713982e-06 "ADRB2/CALCA/ADRA1D/ADRA1A/ADRA2B/ADRA2C/ADRA1B/ADA/ADRA2A/ATP1A2/ADORA2B/CAV1/ABAT/ADORA1" 14 +"GO:0045777" "GO:0045777" "positive regulation of blood pressure" "11/743" "39/17381" 4.52846302235609e-07 6.23265854805658e-06 3.73991207053484e-06 "AVPR1A/AGT/ADRA1D/ADRA1A/ADRA2B/ADRA1B/ADH5/ADRB1/AVPR2/AVP/ADORA1" 11 +"GO:0022898" "GO:0022898" "regulation of transmembrane transporter activity" "28/743" "228/17381" 5.17831596682665e-07 7.10349812538478e-06 4.26246010066313e-06 "APP/CASQ1/CALM1/CACNB4/ADRB2/CALM3/ATP1B3/ACTN2/ATP1B2/CAMK2D/CAV3/CALM2/ATP7A/CACNA2D1/FXYD2/ADRA2A/ATP1A2/CAV1/BCL2/ANK3/CACNA1D/ATP1B1/CACNB1/CASQ2/ACTN4/ANK2/CACNB2/CACNB3" 28 +"GO:0046660" "GO:0046660" "female sex differentiation" "19/743" "117/17381" 5.18994023051809e-07 7.10349812538478e-06 4.26246010066313e-06 "BRCA2/AXL/ACVR1B/ARRB1/CASP2/AFP/AMH/FOXL2/ANG/BAX/ADCYAP1R1/AMHR2/ARRB2/BCL2/BMPR1B/ATM/ADCYAP1/BCL2L1/BAK1" 19 +"GO:0001508" "GO:0001508" "action potential" "21/743" "140/17381" 5.21356980462768e-07 7.10349812538478e-06 4.26246010066313e-06 "CACNA1C/ATP2A2/ADRA1A/ATP1A1/CAMK2D/CAV3/CACNA1F/CACNA2D1/ATP1A2/CACNA1S/CAV1/ANK3/CACNA1B/CACNA1D/ATP1B1/HCN2/CACNA1E/ANK2/CACNB2/CACNA1A/CACNB3" 21 +"GO:0006939" "GO:0006939" "smooth muscle contraction" "18/743" "106/17381" 5.21609524182844e-07 7.10349812538478e-06 4.26246010066313e-06 "BDKRB2/BBS2/ADRB2/AGT/CALCA/ACTA2/ADRA1D/ADRA1A/ADRA2B/ADRA2C/ADRA1B/ADA/ADRA2A/ATP1A2/ADORA2B/CAV1/ABAT/ADORA1" 18 +"GO:0043691" "GO:0043691" "reverse cholesterol transport" "8/743" "19/17381" 5.33711109075258e-07 7.24922569413244e-06 4.34990405241611e-06 "APOC2/APOC3/SCARB1/APOE/APOA4/ABCA1/APOA1/APOA2" 8 +"GO:0003044" "GO:0003044" "regulation of systemic arterial blood pressure mediated by a chemical signal" "12/743" "48/17381" 5.74924057725873e-07 7.76822976170077e-06 4.66133288523107e-06 "ADRB2/AVPR1A/AGT/AVPR1B/ADRA1D/ADRA1A/ADRB3/AGTR1/ADRA1B/ADRB1/AGTR2/AVPR2" 12 +"GO:0010518" "GO:0010518" "positive regulation of phospholipase activity" "12/743" "48/17381" 5.74924057725873e-07 7.76822976170077e-06 4.66133288523107e-06 "APOC2/ARF4/ABL2/AVPR1A/AGT/AVPR1B/ADRA1A/ANG/ADCYAP1R1/AGTR1/ARL1/C5AR1" 12 +"GO:0030641" "GO:0030641" "regulation of cellular pH" "17/743" "96/17381" 5.82200885498919e-07 7.83679638215215e-06 4.70247634423572e-06 "ATP6V1C1/AVPR1A/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/FASLG/ATP6V1G2/ATP6V0C/BCL2/ATP6V0B/ATP1A4/ATP6V1E1/CA2/CA7/AVP/ATP5B" 17 +"GO:0010632" "GO:0010632" "regulation of epithelial cell migration" "26/743" "203/17381" 5.83027363696344e-07 7.83679638215215e-06 4.70247634423572e-06 "ACVRL1/SCARB1/AGT/AKT1/APOE/ADGRB1/BMPR2/KRIT1/ALOX12/ANXA3/AAMP/CD40/APOH/RHOA/AGTR2/CEACAM1/CALR/AQP1/ARSB/RHOB/ANGPT2/ATP5B/ATP5A1/BMP4/ABL1/ANGPT1" 26 +"GO:1901655" "GO:1901655" "cellular response to ketone" "16/743" "86/17381" 6.23161443638789e-07 8.3536925630278e-06 5.01264033784531e-06 "CASP9/KLF9/ADCY1/AKT1/ATP2B1/ADCY6/ADCY5/AR/ACACA/CDC5L/AKR1B1/AGTR2/AQP1/ADCY3/ARG1/ADCY2" 16 +"GO:0007548" "GO:0007548" "sex differentiation" "31/743" "271/17381" 6.24710922104688e-07 8.3536925630278e-06 5.01264033784531e-06 "BRCA2/ATRX/AXL/BCL2L2/BMPR1A/ACVR1B/ARRB1/AR/NR0B1/BOK/CASP2/AFP/AMH/FOXL2/ANG/BAX/ADCYAP1R1/AMHR2/ARRB2/BCL2/BMPR1B/BIK/ATM/BMP6/ADCYAP1/BMP5/ACVR2A/BCL2L1/CCND1/CBL/BAK1" 31 +"GO:0006081" "GO:0006081" "cellular aldehyde metabolic process" "15/743" "76/17381" 6.30623832613887e-07 8.41102663344553e-06 5.04704369563475e-06 "BMP2/ALDH7A1/ALDH9A1/ALDH3A2/BPGM/ADH5/ADH4/ALDH3B1/ALDH1A1/ALDOB/ALDH1A3/BMP6/BMP5/ALDH3A1/AGXT" 15 +"GO:0034433" "GO:0034433" "steroid esterification" "7/743" "14/17381" 6.69162573455074e-07 8.84716517530695e-06 5.30874899916715e-06 "AGT/APOE/APOA4/APOA1/AGTR1/APOA2/APOC1" 7 +"GO:0034434" "GO:0034434" "sterol esterification" "7/743" "14/17381" 6.69162573455074e-07 8.84716517530695e-06 5.30874899916715e-06 "AGT/APOE/APOA4/APOA1/AGTR1/APOA2/APOC1" 7 +"GO:0034435" "GO:0034435" "cholesterol esterification" "7/743" "14/17381" 6.69162573455074e-07 8.84716517530695e-06 5.30874899916715e-06 "AGT/APOE/APOA4/APOA1/AGTR1/APOA2/APOC1" 7 +"GO:0046879" "GO:0046879" "hormone secretion" "33/743" "300/17381" 6.70162077047406e-07 8.84716517530695e-06 5.30874899916715e-06 "ANXA1/SLC25A6/ADM/ACVR2B/CACNA1C/AGT/BTK/ARRB1/ADCY5/BAD/SLC25A5/ADRA2B/CCKAR/BLK/ADRA2C/CASR/FOXL2/ARL2/AGTR1/ADRA2A/CAMK2G/ABAT/CD38/CACNA1D/AGTR2/AQP1/ARNTL/BMP6/ADCYAP1/CACNA1E/CACNA1A/SLC25A4/ADORA1" 33 +"GO:0042180" "GO:0042180" "cellular ketone metabolic process" "28/743" "231/17381" 6.76955122595315e-07 8.91410371356427e-06 5.3489155260645e-06 "ANXA1/BMP2/APOC2/KYAT1/ADM/APOC3/AVPR1A/AKT2/AKT1/APOA4/ATP2B4/ABCD2/AFP/APOA1/CAV1/ACADVL/ADH4/ACADL/ACACB/AKR1B1/CEACAM1/BMP6/BMP5/BRCA1/AVP/APOC1/BHMT/CBR3" 28 +"GO:0042692" "GO:0042692" "muscle cell differentiation" "40/743" "403/17381" 6.81096177271402e-07 8.94586984106473e-06 5.36797681792849e-06 "BMP2/CASQ1/ADM/CDK1/AVPR1A/AGT/CCNB1/AKT1/BIN1/ATP2A2/ADGRB3/ACTA1/ACTN2/ADGRB1/CDH2/BCL9/CAV3/CAPN3/BTG1/CDK9/CDC42/BDNF/ACTG1/ARRB2/BCL2/ACTC1/AGTR2/ACVR1/CALR/BNIP2/CASQ2/CAV2/ZFP36L1/CAPN2/CD53/ANK2/CDH15/JAG1/BMP4/ABL1" 40 +"GO:0022409" "GO:0022409" "positive regulation of cell-cell adhesion" "30/743" "259/17381" 7.25283318891978e-07 9.50212955763541e-06 5.70176093466046e-06 "ANXA1/AIF1/CD6/CD3G/CD4/CD74/AKT1/CD47/AGER/CD80/BAD/CD247/CD3E/CD27/CD3D/CDC42/ADA/BMP7/ALOX15/CAV1/ANK3/BCL6/CD5/CD59/CD44/CD28/ADAM8/CD1D/CD40LG/CD86" 30 +"GO:0045787" "GO:0045787" "positive regulation of cell cycle" "38/743" "374/17381" 7.27503063906977e-07 9.50714231242072e-06 5.70476884243908e-06 "ANXA1/APP/CCNC/CDKN1B/CDC25C/BRCA2/AIF1/ATRX/CDK1/CCNH/CDK4/CCNB1/CXCR5/AKT1/CCND2/CCNT1/CASP2/ASCL1/CDC6/CDK9/CDC42/BAX/CDK2/CDKN1A/CDC25B/CCNT2/BTC/RHOA/ATM/CALR/CCND3/BRCA1/ASNS/CDC25A/CD28/APEX1/CCND1/ABL1" 38 +"GO:1901019" "GO:1901019" "regulation of calcium ion transmembrane transporter activity" "16/743" "87/17381" 7.33740858679994e-07 9.56450615533745e-06 5.7391900652419e-06 "CASQ1/CALM1/CACNB4/CALM3/CAMK2D/CAV3/CALM2/CACNA2D1/ADRA2A/ATP1A2/ATP1B1/CACNB1/CASQ2/ANK2/CACNB2/CACNB3" 16 +"GO:0051279" "GO:0051279" "regulation of release of sequestered calcium ion into cytosol" "15/743" "77/17381" 7.52659371270645e-07 9.78646293046631e-06 5.87237541721345e-06 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CALM3/CAMK2D/CALM2/CAPN3/BAX/CD19/ATP1A2/CASQ2/ANK2/ABL1" 15 +"GO:0007266" "GO:0007266" "Rho protein signal transduction" "24/743" "180/17381" 7.56169292737914e-07 9.80745887197671e-06 5.88497404980041e-06 "ARHGAP5/APOC3/ARHGDIG/ARHGDIA/APOE/ARRB1/ADRA1A/ABR/BCR/ABCA1/CDC42/APOA1/AGTR1/RHOG/ADRA2A/ARHGAP4/BCL6/RHOA/ARHGAP6/RHOB/CDH13/ARHGAP1/ARHGDIB/ABL1" 24 +"GO:0000302" "GO:0000302" "response to reactive oxygen species" "27/743" "219/17381" 7.6319486849409e-07 9.8738336111423e-06 5.92480226857254e-06 "ANXA1/AXL/CDK1/AKT1/APOE/BTK/BAD/APOA4/AREG/CD36/ATP7A/CAT/CDK2/ADA/BMP7/BCL2/AKR1B1/AQP1/RHOB/APOD/CASP3/ARG1/CCNA2/APEX1/BNIP3/ABL1/BAK1" 27 +"GO:0019395" "GO:0019395" "fatty acid oxidation" "17/743" "98/17381" 7.88453209130098e-07 1.01622565857313e-05 6.09787072014386e-06 "ACOX1/AKT2/ACAT1/ACAT2/AKT1/AUH/ABCD2/ACADM/ALDH3A2/ALOX12/ADH7/ACADVL/ACADL/ACACB/ACAA1/ACADS/ABCD1" 17 +"GO:0006182" "GO:0006182" "cGMP biosynthetic process" "11/743" "41/17381" 7.89415873906081e-07 1.01622565857313e-05 6.09787072014386e-06 "ADCY1/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA2B/AQP1/ADCY8/ADCY3/ADCY2" 11 +"GO:0048872" "GO:0048872" "homeostasis of number of cells" "28/743" "233/17381" 8.06955157902643e-07 1.0362265365127e-05 6.21788615858116e-06 "ANXA1/ALAS2/AXL/CDK6/FAS/CD74/AKT1/ACVR1B/ARNT/AMPD3/CDH2/BCR/ADD1/ADAR/CACNA1F/CD7/BAX/ADA/BCL2/BCL6/ZFP36L1/ACVR2A/CASP3/BMP4/ABL1/TNFRSF17/B2M/BAK1" 28 +"GO:0023061" "GO:0023061" "signal release" "41/743" "421/17381" 8.1212363958766e-07 1.0402821373431e-05 6.24222182590828e-06 "ANXA1/SLC25A6/ADM/ACVR2B/CACNA1C/AGT/ATP2A2/BTK/APBA1/ARRB1/ADCY5/BAD/SLC25A5/ADRA2B/CCKAR/BLK/ADRA2C/CASR/FOXL2/ARL2/AGTR1/ADRA2A/CAMK2G/ABAT/BRAF/CD38/CACNA1B/CACNA1D/AGTR2/AQP1/ASIC1/ARNTL/BMP6/ADCYAP1/ADORA2A/CACNA1E/CDK5/CACNA1A/CAMK2A/SLC25A4/ADORA1" 41 +"GO:0001558" "GO:0001558" "regulation of cell growth" "39/743" "391/17381" 8.29973992314346e-07 1.06052232351278e-05 6.36367323541864e-06 "CDKN1B/ACVRL1/BDKRB1/AVPR1A/DDR1/AGT/CDKN2D/APBB2/CDK11B/AKT1/ACVR1B/APOE/CAMK2D/CAV3/CDA/BMPR2/BTG1/FXYD2/CDC42/BDNF/AGTR1/ALOX12/CDKN1A/ARHGAP4/BCL2/BCL6/CD38/OSGIN2/APBB1/AGTR2/CEACAM1/BST2/CDK5/AVP/CDKN2A/ADAM10/CDKN2C/CDH4/ABL1" 39 +"GO:0070665" "GO:0070665" "positive regulation of leukocyte proliferation" "21/743" "144/17381" 8.39834978952396e-07 1.07047931430509e-05 6.42342024347827e-06 "ANXA1/AIF1/CD6/CD4/CD74/AGER/CD80/CD81/CD3E/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/BST1/CD59/CD28/CD1D/CD40LG/CD86" 21 +"GO:0030258" "GO:0030258" "lipid modification" "31/743" "275/17381" 8.59460348617453e-07 1.092802777419e-05 6.55737237403721e-06 "ACOX1/AKT2/AGT/ACAT1/ACAT2/AKT1/APOE/CD80/APOA4/AUH/ABCD2/ACADM/ALDH3A2/APOA1/CD19/AGTR1/ALOX12/ADH7/ACADVL/ACADL/BTC/ACACB/APOA2/ACAA1/APOD/APOC1/ACADS/CD28/ABCD1/CD86/ABO" 31 +"GO:1903708" "GO:1903708" "positive regulation of hemopoiesis" "23/743" "169/17381" 8.90316411038176e-07 1.12926162429475e-05 6.7761439952596e-06 "ANXA1/AXL/CD4/CD74/ACVR1B/AGER/RUNX1/CD80/BTK/ARNT/BAD/CD27/PRDM1/ADA/ATP6AP1/CASP8/BCL6/ZFP36L1/ACVR2A/CA2/ADAM8/JAG1/CD86" 23 +"GO:1901216" "GO:1901216" "positive regulation of neuron death" "15/743" "78/17381" 8.95538808115803e-07 1.13084270146657e-05 6.78563126229621e-06 "CASP9/BAD/CASP2/ASCL1/CDC34/CDC42/BAX/FASLG/CASP8/ATM/PARP1/CASP3/CDK5/ATF4/ABL1" 15 +"GO:0001525" "GO:0001525" "angiogenesis" "44/743" "469/17381" 8.95933348021821e-07 1.13084270146657e-05 6.78563126229621e-06 "ANXA2/KLF5/APLNR/KLK3/ADM/ACVRL1/C6/AGT/ADGRB3/C3AR1/RUNX1/CD34/ADGRB1/C5/ADGRB2/BTG1/KRIT1/ANG/CDC42/ALOX12/FASLG/ANXA3/AAMP/CAV1/CD40/ANPEP/C3/APOH/RHOA/ACVR1/CEACAM1/AQP1/RHOB/C5AR1/ANGPT2/APOD/BRCA1/ATP5B/CDH13/ADAM8/JAG1/BMP4/ABL1/ANGPT1" 44 +"GO:0051271" "GO:0051271" "negative regulation of cellular component movement" "32/743" "290/17381" 9.21871915805025e-07 1.16075113486399e-05 6.96509707164765e-06 "CDKN1B/AIF1/ACVRL1/ACTN1/BMPR1A/APOE/ADGRB1/ABR/ADORA3/BCR/C5/KRIT1/ADA/ADARB1/ARHGAP4/BCL2/BRAF/APOH/RHOA/AGTR2/CALR/RHOB/BST2/ANGPT2/ACTN4/BMP5/APOD/APEX1/LDLRAD4/ARHGDIB/ALOX15B/ADORA1" 32 +"GO:2000377" "GO:2000377" "regulation of reactive oxygen species metabolic process" "23/743" "170/17381" 9.88918728849639e-07 1.2421491315041e-05 7.45352644380796e-06 "BIRC2/ARF4/AIF1/ARG2/AGT/AKT1/ACP5/TSPO/CD34/ADGRB1/ATP2B4/BCR/CD36/AGTR1/BMP7/CDKN1A/CAV1/BCL2/ASS1/AGTR2/BST1/BRCA1/BNIP3" 23 +"GO:0032412" "GO:0032412" "regulation of ion transmembrane transporter activity" "27/743" "222/17381" 9.99285785698443e-07 1.25213170484006e-05 7.51342696013867e-06 "APP/CASQ1/CALM1/CACNB4/ADRB2/CALM3/ATP1B3/ACTN2/ATP1B2/CAMK2D/CAV3/CALM2/ATP7A/CACNA2D1/FXYD2/ADRA2A/ATP1A2/CAV1/ANK3/CACNA1D/ATP1B1/CACNB1/CASQ2/ACTN4/ANK2/CACNB2/CACNB3" 27 +"GO:0010466" "GO:0010466" "negative regulation of peptidase activity" "30/743" "263/17381" 1.00412586397978e-06 1.25515732997472e-05 7.53158224953048e-06 "APP/BIRC2/AGT/CDKN2D/AKT1/SERPINH1/ARRB1/SERPINA3/SERPINC1/CAST/C5/CD27/A2M/SERPINA6/ARRB2/XIAP/APLP2/C3/AQP1/BST2/BIRC3/AMBP/ADORA2A/C4B/BIRC5/AVP/C4A/CD44/AHSG/SERPING1" 30 +"GO:0006066" "GO:0006066" "alcohol metabolic process" "34/743" "320/17381" 1.01497697294534e-06 1.26566405662461e-05 7.59462795228602e-06 "APP/CALM1/SCARB1/ACAT2/ALDH1B1/APOE/ADH1B/APOA4/ACACA/ACLY/ADH1A/ABCA1/ALDH3A2/ADCYAP1R1/APOA1/CAT/ADH7/ADH5/ADH6/ACADVL/ADH4/ALDH3B1/ALDH1A1/ACADL/ALDH3B2/ALDH1A3/ACACB/AKR1B1/APOA2/APOC1/ALDH2/ADH1C/APOB/APOF" 34 +"GO:0097300" "GO:0097300" "programmed necrotic cell death" "11/743" "42/17381" 1.02852748753107e-06 1.27947830480127e-05 7.67752046613527e-06 "BIRC2/CASP1/FAS/BOK/BAX/FASLG/CASP8/CAV1/CD14/BIRC3/SLC25A4" 11 +"GO:0070227" "GO:0070227" "lymphocyte apoptotic process" "14/743" "69/17381" 1.04699377760067e-06 1.29932681033177e-05 7.79662159263407e-06 "CD3G/ARG2/FAS/CD74/AKT1/BTK/CD27/BAX/ADA/FASLG/BCL6/ADAM8/BMP4/BAK1" 14 +"GO:0071887" "GO:0071887" "leukocyte apoptotic process" "17/743" "100/17381" 1.05878648429074e-06 1.30768975088415e-05 7.84680348865141e-06 "ANXA1/AXL/CD3G/ARG2/FAS/CD74/AKT1/BTK/CD27/BAX/ADA/FASLG/BCL6/CDKN2A/ADAM8/BMP4/BAK1" 17 +"GO:0090100" "GO:0090100" "positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway" "17/743" "100/17381" 1.05878648429074e-06 1.30768975088415e-05 7.84680348865141e-06 "BMP2/ACVR2B/ACVRL1/BMPR1A/ACVR1B/BMP8B/BMPR2/BMP7/CDKN2B/ACVR1/PARP1/BMP6/CDKN1C/BMP5/ACVR2A/BMP4/BMP3" 17 +"GO:0090383" "GO:0090383" "phagosome acidification" "9/743" "27/17381" 1.06356204376061e-06 1.30989284776372e-05 7.86002319024249e-06 "ATP6V1C1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1" 9 +"GO:0071902" "GO:0071902" "positive regulation of protein serine/threonine kinase activity" "36/743" "350/17381" 1.06563263557203e-06 1.30989284776372e-05 7.86002319024249e-06 "BMP2/CCNC/CDKN1B/CALM1/ADRB2/CDK1/CCNH/CALM3/CD74/CCNB1/AKT1/AGER/ALK/CCND2/ARRB1/CD81/ATP2B4/ADRA2B/CCNT1/C5/CALM2/CDC6/ADRA2A/ADORA2B/ARAF/BRAF/CD40/CCNT2/RHOA/CCND3/C5AR1/ADAM8/CD40LG/BMP4/CCND1/ADORA1" 36 +"GO:0002475" "GO:0002475" "antigen processing and presentation via MHC class Ib" "6/743" "10/17381" 1.08398993923228e-06 1.32930045865569e-05 7.97647872470744e-06 "CD1E/CD1A/CD1B/CD1C/CD1D/B2M" 6 +"GO:0045834" "GO:0045834" "positive regulation of lipid metabolic process" "19/743" "123/17381" 1.14246962912972e-06 1.39770220585019e-05 8.38692399137157e-06 "ANXA1/APOC2/AVPR1A/SCARB1/AKT2/AGT/AKT1/APOE/CD81/APOA4/ABCD2/AADAC/CDC42/APOA1/AGTR1/APOA2/BMP6/AVP/APOC1" 19 +"GO:0006826" "GO:0006826" "iron ion transport" "13/743" "60/17381" 1.1530711359747e-06 1.4040336773339e-05 8.42491603993901e-06 "ATP6V1C1/ATP6V1B2/ATP6V0A1/ATP7A/ATP6V1B1/ATP6V1A/ATP6AP1/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1/ARHGAP1/B2M" 13 +"GO:0045669" "GO:0045669" "positive regulation of osteoblast differentiation" "13/743" "60/17381" 1.1530711359747e-06 1.4040336773339e-05 8.42491603993901e-06 "BMP2/ACVR2B/BMPR1A/RUNX2/BMPR2/ATP6AP1/BMP7/BMPR1B/ACVR1/BMP6/ACVR2A/JAG1/BMP4" 13 +"GO:0032890" "GO:0032890" "regulation of organic acid transport" "12/743" "51/17381" 1.16435094037521e-06 1.41444040292059e-05 8.48736168546299e-06 "AVPR1A/AKT2/AGT/AKT1/ATP1A2/ABAT/CCK/AGTR2/ADORA2A/AVP/ARG1/ADORA1" 12 +"GO:0055075" "GO:0055075" "potassium ion homeostasis" "7/743" "15/17381" 1.20835922783447e-06 1.46446346698908e-05 8.78752550748594e-06 "ATP12A/ATP1B3/ATP1A3/ATP1B2/ATP1A1/ATP1A2/ATP1B1" 7 +"GO:0010595" "GO:0010595" "positive regulation of endothelial cell migration" "15/743" "80/17381" 1.25655203590152e-06 1.51577081253855e-05 9.09539567147466e-06 "SCARB1/AGT/AKT1/BMPR2/ALOX12/ANXA3/AAMP/CD40/CALR/RHOB/ATP5B/ATP5A1/BMP4/ABL1/ANGPT1" 15 +"GO:0031100" "GO:0031100" "animal organ regeneration" "15/743" "80/17381" 1.25655203590152e-06 1.51577081253855e-05 9.09539567147466e-06 "ADM/AXL/CDK1/CDK4/BAAT/ATIC/APOA1/ANXA3/CDKN1A/APOA2/C5AR1/ANGPT2/CCNA2/CCND1/BAK1" 15 +"GO:0030308" "GO:0030308" "negative regulation of cell growth" "22/743" "160/17381" 1.28526500121565e-06 1.54680148402116e-05 9.28159548001507e-06 "CDKN1B/ACVRL1/BDKRB1/AGT/CDKN2D/APBB2/ACVR1B/CAV3/CDA/BMPR2/BTG1/CDKN1A/ARHGAP4/BCL2/BCL6/OSGIN2/APBB1/AGTR2/BST2/CDK5/CDKN2A/CDKN2C" 22 +"GO:1904385" "GO:1904385" "cellular response to angiotensin" "8/743" "21/17381" 1.33141565160721e-06 1.59196889884305e-05 9.55262293737502e-06 "AGT/ACTN2/CDC6/AGTR1/CAV1/AGTR2/CA2/CAMK2A" 8 +"GO:1900274" "GO:1900274" "regulation of phospholipase C activity" "10/743" "35/17381" 1.33202421874211e-06 1.59196889884305e-05 9.55262293737502e-06 "ABL2/AVPR1A/AGT/AVPR1B/ADRA1A/ANG/ADCYAP1R1/BICD1/C5AR1/ABL1" 10 +"GO:1903514" "GO:1903514" "release of sequestered calcium ion into cytosol by endoplasmic reticulum" "10/743" "35/17381" 1.33202421874211e-06 1.59196889884305e-05 9.55262293737502e-06 "CASQ1/CALM1/CACNA1C/CALM3/CAMK2D/CALM2/ATP1A2/FASLG/CASQ2/ANK2" 10 +"GO:0001101" "GO:0001101" "response to acid chemical" "34/743" "324/17381" 1.34739761090327e-06 1.60663194387659e-05 9.6406086639938e-06 "CDO1/CDKN1B/AQP2/ABL2/AVPR1A/CDK4/CDKN2D/CCNB1/AKT1/BCHE/ADCY6/BAD/ATP1A3/ATP2B4/ACACA/CD9/ASCL1/ABCA1/CD36/ATP7A/ALAD/CAT/AQP3/CD38/AKR1B1/AQP1/BMP6/CAPN2/CASP3/ASNS/ARG1/APOB/AANAT/BCL2L1" 34 +"GO:0046545" "GO:0046545" "development of primary female sexual characteristics" "17/743" "102/17381" 1.41036008153658e-06 1.67784216596593e-05 1.00679062081861e-05 "BRCA2/ACVR1B/ARRB1/CASP2/AFP/AMH/FOXL2/ANG/BAX/ADCYAP1R1/AMHR2/ARRB2/BCL2/BMPR1B/ATM/ADCYAP1/BCL2L1" 17 +"GO:1903039" "GO:1903039" "positive regulation of leukocyte cell-cell adhesion" "27/743" "226/17381" 1.41909178307117e-06 1.68435779298011e-05 1.01070032835827e-05 "ANXA1/AIF1/CD6/CD3G/CD4/CD74/AKT1/CD47/AGER/CD80/BAD/CD247/CD3E/CD27/CD3D/CDC42/ADA/CAV1/BCL6/CD5/CD59/CD44/CD28/ADAM8/CD1D/CD40LG/CD86" 27 +"GO:0006635" "GO:0006635" "fatty acid beta-oxidation" "14/743" "71/17381" 1.5060070637189e-06 1.77935766090075e-05 1.06770508002181e-05 "ACOX1/AKT2/ACAT1/ACAT2/AKT1/AUH/ABCD2/ACADM/ACADVL/ACADL/ACACB/ACAA1/ACADS/ABCD1" 14 +"GO:0086001" "GO:0086001" "cardiac muscle cell action potential" "14/743" "71/17381" 1.5060070637189e-06 1.77935766090075e-05 1.06770508002181e-05 "CACNA1C/ATP2A2/ATP1A1/CAMK2D/CAV3/CACNA2D1/ATP1A2/CAV1/ANK3/CACNA1D/ATP1B1/HCN2/ANK2/CACNB2" 14 +"GO:0051453" "GO:0051453" "regulation of intracellular pH" "16/743" "92/17381" 1.60018137478532e-06 1.88631859100547e-05 1.13188707723695e-05 "ATP6V1C1/AVPR1A/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/FASLG/ATP6V1G2/ATP6V0C/BCL2/ATP6V0B/ATP6V1E1/CA2/CA7/AVP/ATP5B" 16 +"GO:0009914" "GO:0009914" "hormone transport" "33/743" "312/17381" 1.61622342179929e-06 1.90089913813894e-05 1.14063614696361e-05 "ANXA1/SLC25A6/ADM/ACVR2B/CACNA1C/AGT/BTK/ARRB1/ADCY5/BAD/SLC25A5/ADRA2B/CCKAR/BLK/ADRA2C/CASR/FOXL2/ARL2/AGTR1/ADRA2A/CAMK2G/ABAT/CD38/CACNA1D/AGTR2/AQP1/ARNTL/BMP6/ADCYAP1/CACNA1E/CACNA1A/SLC25A4/ADORA1" 33 +"GO:0006919" "GO:0006919" "activation of cysteine-type endopeptidase activity involved in apoptotic process" "15/743" "82/17381" 1.7431889174659e-06 2.04557883172018e-05 1.22745132033044e-05 "CASP1/BID/CASP9/FAS/BAD/BOK/CASP2/BAX/FASLG/CASP8/CCK/CASP7/CASP3/APAF1/BAK1" 15 +"GO:0050870" "GO:0050870" "positive regulation of T cell activation" "26/743" "215/17381" 1.76100221576307e-06 2.06180689289002e-05 1.23718898225793e-05 "ANXA1/AIF1/CD6/CD3G/CD4/CD74/AKT1/CD47/AGER/CD80/BAD/CD247/CD3E/CD27/CD3D/CDC42/ADA/CAV1/BCL6/CD5/CD59/CD28/ADAM8/CD1D/CD40LG/CD86" 26 +"GO:0006639" "GO:0006639" "acylglycerol metabolic process" "18/743" "115/17381" 1.78995747518239e-06 2.0909774117537e-05 1.25469277694857e-05 "APOC2/APOC3/SCARB1/APOE/APOA4/CAV3/AADAC/ANG/APOA1/CAT/CAV1/C3/APOH/APOA2/APOBEC1/APOC1/DAGLA/APOB" 18 +"GO:0035270" "GO:0035270" "endocrine system development" "19/743" "127/17381" 1.87665174951022e-06 2.18731369453049e-05 1.31249944548486e-05 "ANXA1/BMP2/CDK6/AKT1/BMPR1A/TSPO/BAD/NR0B1/ASCL1/APOA1/BRAF/ARNTL/BMP6/ADCYAP1/CDKN1C/BMP5/CDH1/BMP4/BAK1" 19 +"GO:0001701" "GO:0001701" "in utero embryonic development" "33/743" "315/17381" 1.99673688273473e-06 2.32204794789938e-05 1.39334684898107e-05 "BMP2/ADM/BRCA2/ACVRL1/APBA2/C6/BTF3/CCNB1/AKT1/BMPR1A/ACVR1B/APBA1/ARNT/AR/BYSL/ADD1/C5/ADAR/ATP7A/PRDM1/ASCL2/ADA/BMP7/CASP8/ACVR1/ZFP36L1/CDKN1C/CAPN2/BMP5/APOB/ADAM10/BCL2L1/ANGPT1" 33 +"GO:0010881" "GO:0010881" "regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion" "8/743" "22/17381" 2.01401062022965e-06 2.32645199993046e-05 1.39598950415354e-05 "CALM1/CACNA1C/CALM3/CAMK2D/CALM2/ATP1A2/CASQ2/ANK2" 8 +"GO:0035812" "GO:0035812" "renal sodium excretion" "8/743" "22/17381" 2.01401062022965e-06 2.32645199993046e-05 1.39598950415354e-05 "AVPR1A/AGT/AGTR1/AGTR2/ADORA2A/AVPR2/AVP/ADORA1" 8 +"GO:0035813" "GO:0035813" "regulation of renal sodium excretion" "8/743" "22/17381" 2.01401062022965e-06 2.32645199993046e-05 1.39598950415354e-05 "AVPR1A/AGT/AGTR1/AGTR2/ADORA2A/AVPR2/AVP/ADORA1" 8 +"GO:0006638" "GO:0006638" "neutral lipid metabolic process" "18/743" "116/17381" 2.03560999187754e-06 2.34095149065917e-05 1.40468993591549e-05 "APOC2/APOC3/SCARB1/APOE/APOA4/CAV3/AADAC/ANG/APOA1/CAT/CAV1/C3/APOH/APOA2/APOBEC1/APOC1/DAGLA/APOB" 18 +"GO:0051208" "GO:0051208" "sequestering of calcium ion" "18/743" "116/17381" 2.03560999187754e-06 2.34095149065917e-05 1.40468993591549e-05 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CALM3/CAMK2D/CALM2/CAPN3/BAX/CD19/ATP1A2/FASLG/CALR/CASQ2/ATP7B/ANK2/ABL1" 18 +"GO:0008652" "GO:0008652" "cellular amino acid biosynthetic process" "15/743" "83/17381" 2.04484280105338e-06 2.34635509876968e-05 1.40793237556482e-05 "CDO1/BCAT1/ASL/CAD/KYAT1/AHCY/ATP2B4/ASPA/CBS/ABAT/BCAT2/ASS1/ASNS/BHMT/AGXT" 15 +"GO:0060192" "GO:0060192" "negative regulation of lipase activity" "7/743" "16/17381" 2.06893356488475e-06 2.36351682081205e-05 1.41823028149413e-05 "ANXA1/APOC3/APOA1/BICD1/APOA2/APOC1/ABL1" 7 +"GO:0140115" "GO:0140115" "export across plasma membrane" "7/743" "16/17381" 2.06893356488475e-06 2.36351682081205e-05 1.41823028149413e-05 "ATP1B3/ATP1A3/ATP1B2/ATP1A1/FXYD2/ATP1A2/ATP1B1" 7 +"GO:0051955" "GO:0051955" "regulation of amino acid transport" "9/743" "29/17381" 2.10424298116044e-06 2.39855890473684e-05 1.4392573138009e-05 "AVPR1A/AGT/ATP1A2/ABAT/CCK/ADORA2A/AVP/ARG1/ADORA1" 9 +"GO:0002576" "GO:0002576" "platelet degranulation" "19/743" "128/17381" 2.1171701171918e-06 2.40270950799727e-05 1.44174788682267e-05 "APP/ALDOA/CALM1/A1BG/ACTN1/ALB/ACTN2/SERPINA3/CD9/CD36/A2M/APOA1/APLP2/APOH/CD63/ACTN4/ANXA5/AHSG/SERPING1" 19 +"GO:0097553" "GO:0097553" "calcium ion transmembrane import into cytosol" "19/743" "128/17381" 2.1171701171918e-06 2.40270950799727e-05 1.44174788682267e-05 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CALM3/ATP2B4/CAMK2D/CALM2/CAPN3/CACNA2D1/CALCR/BAX/CD19/ATP1A2/FASLG/CASQ2/ANK2/ABL1" 19 +"GO:0034329" "GO:0034329" "cell junction assembly" "25/743" "204/17381" 2.1747124061666e-06 2.46261196978384e-05 1.47769241004065e-05 "ACVRL1/ACTN1/AGT/RUNX1/ACTN2/APC/CD9/CDH5/CDC42/ARL2/ACTN3/ACTB/ACTG1/RHOC/CD151/CAV1/BCL2/CAPZA1/RHOA/CBFB/ARHGAP6/ACTN4/APOD/ANK2/ABL1" 25 +"GO:0030336" "GO:0030336" "negative regulation of cell migration" "29/743" "259/17381" 2.21292291491945e-06 2.50040962548213e-05 1.50037292553721e-05 "AIF1/ACVRL1/BMPR1A/APOE/ADGRB1/ABR/ADORA3/BCR/C5/KRIT1/ADA/ADARB1/ARHGAP4/BCL2/BRAF/APOH/RHOA/AGTR2/CALR/RHOB/BST2/ANGPT2/BMP5/APOD/APEX1/LDLRAD4/ARHGDIB/ALOX15B/ADORA1" 29 +"GO:0032488" "GO:0032488" "Cdc42 protein signal transduction" "6/743" "11/17381" 2.29833114072675e-06 2.58562253331759e-05 1.55150500346542e-05 "APOC3/APOE/ABCA1/CDC42/APOA1/ABL1" 6 +"GO:0034372" "GO:0034372" "very-low-density lipoprotein particle remodeling" "6/743" "11/17381" 2.29833114072675e-06 2.58562253331759e-05 1.55150500346542e-05 "APOC2/APOC3/APOE/APOA4/APOA1/APOA2" 6 +"GO:0018107" "GO:0018107" "peptidyl-threonine phosphorylation" "18/743" "117/17381" 2.31135834984585e-06 2.59463762699615e-05 1.55691451810601e-05 "APP/CAD/CALM1/CDK1/CAMK2B/CALM3/AKT1/ACVR1B/AZU1/CAMK2D/CALM2/BMP7/CAMK2G/BCL2/ACVR1/GRK2/CDK5/CAMK2A" 18 +"GO:0016049" "GO:0016049" "cell growth" "44/743" "486/17381" 2.31899760322863e-06 2.59757848413597e-05 1.55867918193768e-05 "APP/CDKN1B/ALCAM/ACVRL1/BDKRB1/AVPR1A/DDR1/AGT/CDKN2D/APBB2/CDK11B/AKT1/ACVR1B/APOE/ADRA1A/AR/CAMK2D/CAV3/CDA/BMPR2/FOXL2/BTG1/FXYD2/CDC42/BDNF/AGTR1/ALOX12/CDKN1A/ARHGAP4/BCL2/BCL6/CD38/OSGIN2/APBB1/AGTR2/CEACAM1/BST2/CDK5/AVP/CDKN2A/ADAM10/CDKN2C/CDH4/ABL1" 44 +"GO:0043271" "GO:0043271" "negative regulation of ion transport" "20/743" "141/17381" 2.37399327901006e-06 2.65343741228447e-05 1.59219737935198e-05 "CALM1/CALM3/AKT2/AKT1/ACTN2/CAMK2D/CAV3/CALM2/ATP7A/ADRA2A/ATP1A2/CAV1/BCL2/ABAT/ANK3/AGTR2/CASQ2/ADCYAP1/ATF4/ADORA1" 20 +"GO:0030301" "GO:0030301" "cholesterol transport" "15/743" "84/17381" 2.3924306118556e-06 2.66828198628291e-05 1.60110487862387e-05 "APOC2/ANXA2/APOC3/SCARB1/ABCA2/TSPO/APOE/APOA4/ABCA1/CD36/APOA1/CAV1/APOA2/APOC1/APOB" 15 +"GO:0010565" "GO:0010565" "regulation of cellular ketone metabolic process" "22/743" "166/17381" 2.402582474618e-06 2.67384178626842e-05 1.60444104134083e-05 "ANXA1/BMP2/APOC2/APOC3/AVPR1A/AKT2/AKT1/APOA4/ATP2B4/ABCD2/APOA1/CAV1/ACADVL/ACADL/ACACB/CEACAM1/BMP6/BMP5/BRCA1/AVP/APOC1/BHMT" 22 +"GO:0045861" "GO:0045861" "negative regulation of proteolysis" "35/743" "348/17381" 2.51054828562513e-06 2.78800158328542e-05 1.67294272477843e-05 "APP/BIRC2/C4BPA/AGT/CDKN2D/AKT1/SERPINH1/ARRB1/SERPINA3/SERPINC1/CAST/C5/CD27/A2M/ALAD/SERPINA6/ARRB2/XIAP/APLP2/C4BPB/C3/AQP1/BST2/BIRC3/AMBP/ADORA2A/C4B/CDK5/BIRC5/AVP/C4A/CD59/CD44/AHSG/SERPING1" 35 +"GO:0030183" "GO:0030183" "B cell differentiation" "18/743" "118/17381" 2.62043529888157e-06 2.90380142863214e-05 1.74242852061323e-05 "CD79A/BTK/BAD/CD27/PRDM1/BAX/ADA/ZFP36L2/CD79B/BCL2/BCL6/BCL3/ATM/ZFP36L1/CD40LG/CDH17/ABL1/BAK1" 18 +"GO:0001935" "GO:0001935" "endothelial cell proliferation" "19/743" "130/17381" 2.68383627923672e-06 2.96137585182303e-05 1.77697610228893e-05 "BMP2/ACVRL1/SCARB1/AKT1/APOE/ARNT/CD34/BMPR2/KRIT1/ANG/APOA1/CAV1/APOH/BMP6/CAV2/CDH13/ARG1/ATP5A1/BMP4" 19 +"GO:2001056" "GO:2001056" "positive regulation of cysteine-type endopeptidase activity" "19/743" "130/17381" 2.68383627923672e-06 2.96137585182303e-05 1.77697610228893e-05 "CASP1/BID/CASP9/FAS/ASPH/ARRB1/BAD/BOK/CASP2/FOXL2/BAX/ALOX12/FASLG/CASP8/CCK/CASP7/CASP3/APAF1/BAK1" 19 +"GO:0045776" "GO:0045776" "negative regulation of blood pressure" "11/743" "46/17381" 2.74179696699553e-06 3.01248392870527e-05 1.8076435473543e-05 "ADRB2/BDKRB1/CALCA/ADRA1A/ADRB3/BBS4/BMPR2/ADRB1/ABAT/AGTR2/ADORA1" 11 +"GO:0050766" "GO:0050766" "positive regulation of phagocytosis" "11/743" "46/17381" 2.74179696699553e-06 3.01248392870527e-05 1.8076435473543e-05 "C2/CD47/AZU1/ABR/BCR/CD36/C3/CALR/C4B/C4A/AHSG" 11 +"GO:0048146" "GO:0048146" "positive regulation of fibroblast proliferation" "12/743" "55/17381" 2.75000451373964e-06 3.01398301481138e-05 1.80854307524914e-05 "ANXA2/CDK4/CDK6/CD74/AGT/CCNB1/CDC6/CDKN1A/BTC/BMI1/AQP1/CCNA2" 12 +"GO:0006979" "GO:0006979" "response to oxidative stress" "40/743" "426/17381" 2.75480959614644e-06 3.01398301481138e-05 1.80854307524914e-05 "ANXA1/APP/AIF1/AXL/CDK1/AKT1/ATP2A2/APOE/BTK/ARNT/BAD/APOA4/ATOX1/AREG/CD36/ATP7A/ALAD/NUDT2/CAT/CDK2/ADA/BMP7/CA3/BCL2/ALDH3B1/CD38/AKR1B1/AQP1/RHOB/PARP1/ARNTL/APOD/CASP3/ARG1/CCNA2/APEX1/BNIP3/ATF4/ABL1/BAK1" 40 +"GO:0015837" "GO:0015837" "amine transport" "15/743" "85/17381" 2.79198076070329e-06 3.04178956560832e-05 1.82522841973954e-05 "AVPR1A/AGT/ADRA2B/ADRA2C/ADRA2A/ATP1A2/ABAT/AQP9/CCK/AGTR2/ADORA2A/GRK2/AVP/ARG1/ADORA1" 15 +"GO:0045778" "GO:0045778" "positive regulation of ossification" "15/743" "85/17381" 2.79198076070329e-06 3.04178956560832e-05 1.82522841973954e-05 "BMP2/ADRB2/ACVR2B/CALCA/BMPR1A/RUNX2/BMPR2/ATP6AP1/BMP7/BMPR1B/ACVR1/BMP6/ACVR2A/JAG1/BMP4" 15 +"GO:0001649" "GO:0001649" "osteoblast differentiation" "25/743" "207/17381" 2.84027208022888e-06 3.08790084352615e-05 1.85289753133021e-05 "BMP2/ALPL/ACVR2B/AMELX/CDK6/AKT1/BMPR1A/RUNX2/BGLAP/ADAR/AREG/BMPR2/CAT/ACHE/ATP6AP1/BMP7/BMPR1B/CBFB/ACVR1/BMP6/ACVR2A/ATP5B/JAG1/BMP4/BMP3" 25 +"GO:0010880" "GO:0010880" "regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" "9/743" "30/17381" 2.89259974736738e-06 3.13819783912499e-05 1.88307828638062e-05 "CASQ1/CALM1/CACNA1C/CALM3/CAMK2D/CALM2/ATP1A2/CASQ2/ANK2" 9 +"GO:0046631" "GO:0046631" "alpha-beta T cell activation" "18/743" "119/17381" 2.96636987125547e-06 3.20500743576015e-05 1.92316744174777e-05 "ANXA1/ARG2/AGER/CD80/CD3E/ATP7A/PRDM1/ADA/BCL2/TNFSF8/BRAF/BCL6/BCL3/BMX/ADORA2A/CD28/CD86/ABL1" 18 +"GO:0045940" "GO:0045940" "positive regulation of steroid metabolic process" "8/743" "23/17381" 2.97276052012536e-06 3.20500743576015e-05 1.92316744174777e-05 "AGT/APOE/APOA4/APOA1/AGTR1/APOA2/BMP6/APOC1" 8 +"GO:0051882" "GO:0051882" "mitochondrial depolarization" "8/743" "23/17381" 2.97276052012536e-06 3.20500743576015e-05 1.92316744174777e-05 "CASP1/TSPO/BOK/ALOX12/BCL2/CCK/PARP1/ABL1" 8 +"GO:0030879" "GO:0030879" "mammary gland development" "19/743" "131/17381" 3.01580728741433e-06 3.23792587393551e-05 1.94292017861373e-05 "CDO1/ARHGAP5/BRCA2/DDR1/AKT2/AKT1/AR/SERPINC1/CAV3/AREG/ATP7A/BAX/CAPN1/APRT/CAV1/ATP7B/ARG1/BMP4/CCND1" 19 +"GO:0031214" "GO:0031214" "biomineral tissue development" "19/743" "131/17381" 3.01580728741433e-06 3.23792587393551e-05 1.94292017861373e-05 "BMP2/ALPL/ADRB2/ACVR2B/AMELX/BMPR1A/BGLAP/ASGR2/BMPR2/BMP7/ALOX15/BMPR1B/ACVR1/BMP6/ACVR2A/AMBN/AHSG/BMP4/AMELY" 19 +"GO:0051281" "GO:0051281" "positive regulation of release of sequestered calcium ion into cytosol" "10/743" "38/17381" 3.05319014852808e-06 3.27127515913722e-05 1.96293144560484e-05 "CASQ1/CALM1/APLNR/BDKRB1/CALM3/CALM2/CAPN3/BAX/CD19/ABL1" 10 +"GO:0097193" "GO:0097193" "intrinsic apoptotic signaling pathway" "31/743" "292/17381" 3.08031014428997e-06 3.29351342907037e-05 1.97627553842006e-05 "BDKRB2/BCL2A1/CASP4/BRCA2/BID/CASP9/CD74/CDKN2D/BCL2L2/AKT1/BAD/BOK/CASP2/BAX/CDKN1A/CAV1/BCL2/ATP2A1/BCL3/ATM/PARP1/CASP3/BRCA1/CD44/APAF1/BCL2L1/BNIP3/ATF4/PTTG1IP/ABL1/BAK1" 31 +"GO:0002698" "GO:0002698" "negative regulation of immune effector process" "17/743" "108/17381" 3.1862470828174e-06 3.39276309744446e-05 2.03583038646553e-05 "ANXA1/C4BPA/ABR/BCR/A2M/APOA1/ARRB2/BCL6/C4BPB/APOA2/CEACAM1/BST2/CD59/ARG1/C1QBP/SERPING1/ANGPT1" 17 +"GO:0019218" "GO:0019218" "regulation of steroid metabolic process" "17/743" "108/17381" 3.1862470828174e-06 3.39276309744446e-05 2.03583038646553e-05 "BMP2/AGT/TSPO/APOE/APOA4/ACACA/ATP1A1/APOA1/AGTR1/ACADVL/ACADL/ACACB/APOA2/BMP6/BMP5/APOC1/APOB" 17 +"GO:0043523" "GO:0043523" "regulation of neuron apoptotic process" "24/743" "195/17381" 3.20607313754175e-06 3.40686416566295e-05 2.04429174446086e-05 "AARS/AXL/CASP9/APOE/BOK/CASP2/ASCL1/CDC34/CDC42/BAX/BDNF/FASLG/BCL2/BRAF/ATM/PARP1/C5AR1/ADORA2A/CASP3/CDK5/ADAM8/BCL2L1/ATF4/ANGPT1" 24 +"GO:0043280" "GO:0043280" "positive regulation of cysteine-type endopeptidase activity involved in apoptotic process" "18/743" "120/17381" 3.35300950516649e-06 3.55570167812225e-05 2.13360182058696e-05 "CASP1/BID/CASP9/FAS/ARRB1/BAD/BOK/CASP2/FOXL2/BAX/ALOX12/FASLG/CASP8/CCK/CASP7/CASP3/APAF1/BAK1" 18 +"GO:0018209" "GO:0018209" "peptidyl-serine modification" "32/743" "308/17381" 3.39847665933776e-06 3.59654738488199e-05 2.15811132171917e-05 "APP/BDKRB2/ATR/CDK1/CAMK2B/AKT2/CCNB1/AKT1/ARRB1/ATP2B4/CAMK2D/CALCR/CDC42/BGN/BAX/CDK2/CAMK2G/ARAF/ARRB2/CAV1/BCL2/BRAF/ATM/PARP1/CAMK4/GRK2/CDK5/AVP/CD44/CAMK2A/BAK1/ANGPT1" 32 +"GO:0001667" "GO:0001667" "ameboidal-type cell migration" "35/743" "353/17381" 3.46535837665346e-06 3.6598427753432e-05 2.19609177467835e-05 "ACVRL1/SCARB1/AGT/AKT1/ACVR1B/APOE/ADGRB1/BMPR2/KRIT1/APOA1/ALOX12/BMP7/ANXA3/AAMP/ARHGAP4/BRAF/CD40/APOH/RHOA/AGTR2/ACVR1/CEACAM1/CALR/AQP1/ARSB/RHOB/ANGPT2/ATP5B/CDH13/ATP5A1/BMP4/ARHGDIB/C1QBP/ABL1/ANGPT1" 35 +"GO:0070167" "GO:0070167" "regulation of biomineral tissue development" "14/743" "76/17381" 3.52750311444532e-06 3.7178877020885e-05 2.23092168241263e-05 "BMP2/ADRB2/ACVR2B/AMELX/BMPR1A/BGLAP/BMPR2/BMP7/BMPR1B/ACVR1/BMP6/ACVR2A/AHSG/BMP4" 14 +"GO:0061448" "GO:0061448" "connective tissue development" "27/743" "237/17381" 3.54813979483426e-06 3.73203728420067e-05 2.23941215121118e-05 "BMP2/BBS2/ACVRL1/CDK4/AMELX/ACAT1/BMPR1A/SERPINH1/ACTA2/RUNX1/RUNX2/CD34/BMP8B/BBS4/CASR/ATP7A/BMPR2/BMP1/BMP7/BMPR1B/BMP6/BMP5/RUNX3/NKX3-2/CD44/BMP4/BMP3" 27 +"GO:0030330" "GO:0030330" "DNA damage response, signal transduction by p53 class mediator" "17/743" "109/17381" 3.62731106535246e-06 3.79986533667995e-05 2.28011243187508e-05 "CDKN1B/ATR/CDC25C/BRCA2/ATRX/CDK1/CD74/CCNB1/CASP2/BAX/CDK2/CDKN1A/BCL3/ATM/BRCA1/CD44/PTTG1IP" 17 +"GO:0032368" "GO:0032368" "regulation of lipid transport" "17/743" "109/17381" 3.62731106535246e-06 3.79986533667995e-05 2.28011243187508e-05 "APOC2/ANXA2/APOC3/AKT2/AGT/AKT1/ABCA2/TSPO/APOE/APOA4/ABCA1/APOA1/AGTR1/APOA2/AGTR2/BMP6/APOC1" 17 +"GO:0008202" "GO:0008202" "steroid metabolic process" "32/743" "309/17381" 3.64046176572475e-06 3.80593730053042e-05 2.28375591895545e-05 "APP/BMP2/STS/ADM/SCARB1/BAAT/AGT/ACAT2/TSPO/APOE/APOA4/NR0B1/ACACA/ATP1A1/ACLY/ABCA1/AFP/APOA1/AGTR1/CAT/SERPINA6/ACADVL/ACADL/ACACB/AKR1B1/APOA2/ACAA1/BMP6/BMP5/APOC1/APOB/APOF" 32 +"GO:1901214" "GO:1901214" "regulation of neuron death" "30/743" "280/17381" 3.67948275324068e-06 3.83758003119924e-05 2.30274316644551e-05 "AARS/AXL/CASP9/AKT1/APOE/BAD/CD34/BOK/CASP2/ASCL1/CDC34/CDC42/BAX/BDNF/FASLG/CASP8/BCL2/BRAF/ATM/PARP1/C5AR1/ADORA2A/CASP3/CDK5/ADAM8/BCL2L1/ATF4/ABL1/CBL/ANGPT1" 30 +"GO:0014074" "GO:0014074" "response to purine-containing compound" "20/743" "145/17381" 3.68555995266864e-06 3.83758003119924e-05 2.30274316644551e-05 "CDO1/APP/BIRC2/CASP1/AQP8/BSG/AREG/CACNA1S/AQP9/BRAF/HCN2/AQP1/CASQ2/ZFP36L1/ADORA2A/ALDH3A1/APEX1/AANAT/ADSS/AGXT" 20 +"GO:0006641" "GO:0006641" "triglyceride metabolic process" "16/743" "98/17381" 3.78782405683525e-06 3.93016908745108e-05 2.35830130851374e-05 "APOC2/APOC3/SCARB1/APOE/APOA4/CAV3/AADAC/APOA1/CAT/CAV1/C3/APOH/APOA2/APOBEC1/APOC1/APOB" 16 +"GO:1902107" "GO:1902107" "positive regulation of leukocyte differentiation" "19/743" "133/17381" 3.79350130078194e-06 3.93016908745108e-05 2.35830130851374e-05 "ANXA1/AXL/CD4/CD74/AGER/RUNX1/CD80/BTK/BAD/CD27/PRDM1/ADA/ATP6AP1/CASP8/BCL6/ZFP36L1/CA2/ADAM8/CD86" 19 +"GO:0045137" "GO:0045137" "development of primary sexual characteristics" "26/743" "224/17381" 3.79726481879331e-06 3.93016908745108e-05 2.35830130851374e-05 "BRCA2/ATRX/BCL2L2/ACVR1B/ARRB1/AR/NR0B1/BOK/CASP2/AFP/AMH/FOXL2/ANG/BAX/ADCYAP1R1/AMHR2/ARRB2/BCL2/BMPR1B/BIK/ATM/ADCYAP1/ACVR2A/BCL2L1/CCND1/CBL" 26 +"GO:0032147" "GO:0032147" "activation of protein kinase activity" "33/743" "325/17381" 3.94566425721237e-06 4.07561128364751e-05 2.44557402222429e-05 "BMP2/ADRB2/ACVR2B/CDK1/CD74/AGT/ADCY1/CALCA/AKT1/ALK/ADCY6/ARRB1/CD81/ADCY5/ADCY9/ADCY7/ADRA2B/C5/ADRA2C/ANG/ADRA2A/ADORA2B/ARAF/BRAF/ADCY8/ADCY3/C5AR1/CD40LG/ADCY2/BMP4/ABL1/ANGPT1/ADORA1" 33 +"GO:0051047" "GO:0051047" "positive regulation of secretion" "37/743" "386/17381" 4.04160742050034e-06 4.16639808786639e-05 2.50005072142504e-05 "CASP1/AVPR1A/AGT/ARRB1/ARF1/BAD/CASP5/CD34/AP1G1/C5/BLK/CASR/FOXL2/ANG/ACHE/ATP6AP1/ADORA2B/ABAT/CD38/CCK/APBB1/CD2/AGTR2/CD14/AQP1/ALOX12B/BMP6/ADCYAP1/ADORA2A/GRK2/CDK5/AVP/CD58/ADAM8/ABL1/ALOX15B/ADORA1" 37 +"GO:0051952" "GO:0051952" "regulation of amine transport" "14/743" "77/17381" 4.14413505737304e-06 4.26359819520984e-05 2.55837572862833e-05 "AVPR1A/AGT/ADRA2B/ADRA2C/ADRA2A/ATP1A2/ABAT/CCK/AGTR2/ADORA2A/GRK2/AVP/ARG1/ADORA1" 14 +"GO:1990776" "GO:1990776" "response to angiotensin" "8/743" "24/17381" 4.29260544205341e-06 4.38512186105976e-05 2.63129610783144e-05 "AGT/ACTN2/CDC6/AGTR1/CAV1/AGTR2/CA2/CAMK2A" 8 +"GO:0033762" "GO:0033762" "response to glucagon" "11/743" "48/17381" 4.29506174757795e-06 4.38512186105976e-05 2.63129610783144e-05 "CDO1/ADCY1/ADCY6/ADCY5/ADCY9/ADCY7/ADCY8/ADCY3/ARG1/CCNA2/ADCY2" 11 +"GO:2000273" "GO:2000273" "positive regulation of receptor activity" "11/743" "48/17381" 4.29506174757795e-06 4.38512186105976e-05 2.63129610783144e-05 "ANXA2/CALM1/ADRB2/CALM3/ACTN2/ADRA2B/ADRA2C/CALM2/ADRA2A/CDK5/ADORA1" 11 +"GO:0030500" "GO:0030500" "regulation of bone mineralization" "13/743" "67/17381" 4.29614837402377e-06 4.38512186105976e-05 2.63129610783144e-05 "BMP2/ADRB2/ACVR2B/BMPR1A/BGLAP/BMPR2/BMP7/BMPR1B/ACVR1/BMP6/ACVR2A/AHSG/BMP4" 13 +"GO:0051341" "GO:0051341" "regulation of oxidoreductase activity" "15/743" "88/17381" 4.37294057899032e-06 4.45471801107773e-05 2.67305733692943e-05 "CALM1/ABL2/SCARB1/AGT/AKT1/CDH3/APOE/ATP2B4/CAV3/ATP7A/AGTR1/CAV1/AGTR2/ACVR2A/ABL1" 15 +"GO:0034384" "GO:0034384" "high-density lipoprotein particle clearance" "6/743" "12/17381" 4.4301629316405e-06 4.48651529769855e-05 2.69213732585014e-05 "APOC2/APOC3/SCARB1/APOE/APOA1/APOA2" 6 +"GO:0038166" "GO:0038166" "angiotensin-activated signaling pathway" "6/743" "12/17381" 4.4301629316405e-06 4.48651529769855e-05 2.69213732585014e-05 "ACTN2/AGTR1/CAV1/AGTR2/CA2/CAMK2A" 6 +"GO:0046033" "GO:0046033" "AMP metabolic process" "6/743" "12/17381" 4.4301629316405e-06 4.48651529769855e-05 2.69213732585014e-05 "ADK/AMPD3/APRT/AK4/ADSL/ADSS" 6 +"GO:0051260" "GO:0051260" "protein homooligomerization" "32/743" "312/17381" 4.46487802945706e-06 4.50775122073352e-05 2.70487995955533e-05 "ANXA6/ALDOA/BID/CD3G/FAS/ACAT1/CD79A/APOE/CD247/ACTN2/ACACA/APC/CD3E/CDA/CD3D/ALAD/BAX/CAT/ACPP/RHOC/CD79B/CAV1/ACADL/C9/ALDH1A3/BLM/BIK/ACACB/ASIC1/ALOX5AP/ARG1/APAF1" 32 +"GO:0046883" "GO:0046883" "regulation of hormone secretion" "28/743" "254/17381" 4.46855338403149e-06 4.50775122073352e-05 2.70487995955533e-05 "ANXA1/SLC25A6/CACNA1C/AGT/ARRB1/ADCY5/BAD/SLC25A5/ADRA2B/CCKAR/BLK/ADRA2C/CASR/FOXL2/ARL2/AGTR1/ADRA2A/ABAT/CD38/CACNA1D/AGTR2/ARNTL/BMP6/ADCYAP1/CACNA1E/CACNA1A/SLC25A4/ADORA1" 28 +"GO:0046902" "GO:0046902" "regulation of mitochondrial membrane permeability" "14/743" "78/17381" 4.85476548689805e-06 4.88782322854035e-05 2.93294249157265e-05 "BNIP3L/SLC25A6/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BCL2L1/BNIP3/CAMK2A/SLC25A4/BAK1" 14 +"GO:0009416" "GO:0009416" "response to light stimulus" "31/743" "299/17381" 5.03204871809672e-06 5.05647613905836e-05 3.03414281418198e-05 "APP/CALM1/ATR/BRCA2/CASP9/AKT2/CDKN2D/AKT1/ASIC2/ARRB1/ATP1A3/AGRP/CACNA1F/OPN1SW/BAX/CAT/ATP1A2/CDKN1A/BCL2/BRAF/BCL3/AQP1/ABCA4/CASP3/CDK5/ASNS/CDC25A/AANAT/CCND1/ATF4/BAK1" 31 +"GO:0032092" "GO:0032092" "positive regulation of protein binding" "15/743" "89/17381" 5.05470791468787e-06 5.06940183304452e-05 3.04189888786805e-05 "APP/BMP2/ANXA2/APOE/ARRB1/AMFR/ADD1/ADD2/KRIT1/BDNF/CAV1/CDK5/BMP4/ABL1/B2M" 15 +"GO:0090075" "GO:0090075" "relaxation of muscle" "9/743" "32/17381" 5.25110979899516e-06 5.25618824174081e-05 3.15398023150478e-05 "ATP2A2/ATP1A1/CAMK2D/ATP1A2/CAMK2G/ADORA2B/ATP2A1/ATP1B1/ADORA1" 9 +"GO:0043525" "GO:0043525" "positive regulation of neuron apoptotic process" "11/743" "49/17381" 5.32646528218274e-06 5.32132390642773e-05 3.19306494258059e-05 "CASP9/CASP2/ASCL1/CDC34/CDC42/BAX/FASLG/ATM/CASP3/CDK5/ATF4" 11 +"GO:0018210" "GO:0018210" "peptidyl-threonine modification" "18/743" "124/17381" 5.39605449387179e-06 5.38045896065251e-05 3.22854898223746e-05 "APP/CAD/CALM1/CDK1/CAMK2B/CALM3/AKT1/ACVR1B/AZU1/CAMK2D/CALM2/BMP7/CAMK2G/BCL2/ACVR1/GRK2/CDK5/CAMK2A" 18 +"GO:0043393" "GO:0043393" "regulation of protein binding" "24/743" "202/17381" 5.94465600162037e-06 5.91607592468951e-05 3.54994639772877e-05 "APP/BMP2/ANXA2/ADRB2/AES/APOE/ARRB1/AMFR/ADD1/ADD2/CD36/KRIT1/CDC42/BAX/BDNF/ARRB2/CAV1/BCL2/CDK5/BMP4/ABL1/B2M/BAK1/ANGPT1" 24 +"GO:0071156" "GO:0071156" "regulation of cell cycle arrest" "17/743" "113/17381" 5.99352323297519e-06 5.95325964119896e-05 3.57225851849213e-05 "CDKN1B/CDC25C/CDK1/CDK4/AKT2/CCNB1/BIN1/CASP2/CDK9/BAX/CDK2/CDKN1A/ATM/CALR/BRCA1/CDK5/CCND1" 17 +"GO:0044062" "GO:0044062" "regulation of excretion" "8/743" "25/17381" 6.07701212325311e-06 6.01310472998754e-05 3.6081686149938e-05 "AVPR1A/AGT/AGTR1/AGTR2/ADORA2A/AVPR2/AVP/ADORA1" 8 +"GO:0045922" "GO:0045922" "negative regulation of fatty acid metabolic process" "8/743" "25/17381" 6.07701212325311e-06 6.01310472998754e-05 3.6081686149938e-05 "APOC3/AKT1/ACADVL/ACADL/ACACB/CEACAM1/BRCA1/APOC1" 8 +"GO:0045765" "GO:0045765" "regulation of angiogenesis" "29/743" "273/17381" 6.30206241459158e-06 6.22388797624264e-05 3.7346492814474e-05 "APLNR/KLK3/ADM/ACVRL1/C6/AGT/ADGRB3/C3AR1/RUNX1/CD34/ADGRB1/C5/ADGRB2/BTG1/KRIT1/ALOX12/FASLG/ANXA3/CD40/C3/APOH/RHOA/CEACAM1/AQP1/RHOB/C5AR1/ANGPT2/BRCA1/ABL1" 29 +"GO:0010955" "GO:0010955" "negative regulation of protein processing" "10/743" "41/17381" 6.4458897896731e-06 6.34172617139892e-05 3.80535819082162e-05 "BIRC2/C4BPA/CAST/A2M/XIAP/C4BPB/BIRC3/BIRC5/CD59/SERPING1" 10 +"GO:1903318" "GO:1903318" "negative regulation of protein maturation" "10/743" "41/17381" 6.4458897896731e-06 6.34172617139892e-05 3.80535819082162e-05 "BIRC2/C4BPA/CAST/A2M/XIAP/C4BPB/BIRC3/BIRC5/CD59/SERPING1" 10 +"GO:0032371" "GO:0032371" "regulation of sterol transport" "11/743" "50/17381" 6.56760163445766e-06 6.43699592013606e-05 3.86252488469899e-05 "APOC2/ANXA2/APOC3/ABCA2/TSPO/APOE/APOA4/ABCA1/APOA1/APOA2/APOC1" 11 +"GO:0032374" "GO:0032374" "regulation of cholesterol transport" "11/743" "50/17381" 6.56760163445766e-06 6.43699592013606e-05 3.86252488469899e-05 "APOC2/ANXA2/APOC3/ABCA2/TSPO/APOE/APOA4/ABCA1/APOA1/APOA2/APOC1" 11 +"GO:0015918" "GO:0015918" "sterol transport" "15/743" "91/17381" 6.70876675947638e-06 6.55054112835665e-05 3.93065778360582e-05 "APOC2/ANXA2/APOC3/SCARB1/ABCA2/TSPO/APOE/APOA4/ABCA1/CD36/APOA1/CAV1/APOA2/APOC1/APOB" 15 +"GO:1904019" "GO:1904019" "epithelial cell apoptotic process" "15/743" "91/17381" 6.70876675947638e-06 6.55054112835665e-05 3.93065778360582e-05 "BID/FAS/BOK/CAST/BMPR2/KRIT1/FASLG/BRAF/CD40/ARF6/ZFP36L1/BCL2L1/CD40LG/ABL1/ANGPT1" 15 +"GO:2000146" "GO:2000146" "negative regulation of cell motility" "29/743" "274/17381" 6.76848729926944e-06 6.59640711369479e-05 3.95817970717511e-05 "AIF1/ACVRL1/BMPR1A/APOE/ADGRB1/ABR/ADORA3/BCR/C5/KRIT1/ADA/ADARB1/ARHGAP4/BCL2/BRAF/APOH/RHOA/AGTR2/CALR/RHOB/BST2/ANGPT2/BMP5/APOD/APEX1/LDLRAD4/ARHGDIB/ALOX15B/ADORA1" 29 +"GO:0071312" "GO:0071312" "cellular response to alkaloid" "9/743" "33/17381" 6.94808298781488e-06 6.75248301492946e-05 4.05183318465129e-05 "AIF1/CACNA1S/CASP6/BLM/CASQ2/CASP7/CASP3/CCNA2/BCL2L1" 9 +"GO:0018105" "GO:0018105" "peptidyl-serine phosphorylation" "30/743" "289/17381" 6.95473129846841e-06 6.75248301492946e-05 4.05183318465129e-05 "APP/BDKRB2/ATR/CDK1/CAMK2B/AKT2/CCNB1/AKT1/ARRB1/ATP2B4/CAMK2D/CALCR/CDC42/BAX/CDK2/CAMK2G/ARAF/ARRB2/CAV1/BCL2/BRAF/ATM/CAMK4/GRK2/CDK5/AVP/CD44/CAMK2A/BAK1/ANGPT1" 30 +"GO:0010631" "GO:0010631" "epithelial cell migration" "28/743" "260/17381" 6.99439064199521e-06 6.77827183002345e-05 4.0673077851145e-05 "ACVRL1/SCARB1/AGT/AKT1/APOE/ADGRB1/BMPR2/KRIT1/APOA1/ALOX12/ANXA3/AAMP/CD40/APOH/RHOA/AGTR2/CEACAM1/CALR/AQP1/ARSB/RHOB/ANGPT2/ATP5B/CDH13/ATP5A1/BMP4/ABL1/ANGPT1" 28 +"GO:1901605" "GO:1901605" "alpha-amino acid metabolic process" "25/743" "218/17381" 7.19654851565601e-06 6.96114739598502e-05 4.17704242423714e-05 "CDO1/BCAT1/ASL/CAD/KYAT1/ALDH7A1/AHCY/BAAT/ARG2/ACAT1/ATP2B4/AMT/AUH/ASPA/ATP7A/BLMH/CBS/BCAT2/ASS1/ASNS/ARG1/ART4/ADSS/BHMT/AGXT" 25 +"GO:2000106" "GO:2000106" "regulation of leukocyte apoptotic process" "14/743" "81/17381" 7.67923756727426e-06 7.41418925571722e-05 4.44889057805559e-05 "ANXA1/AXL/CD3G/ARG2/FAS/CD74/BTK/CD27/BAX/ADA/BCL6/CDKN2A/ADAM8/BMP4" 14 +"GO:0046040" "GO:0046040" "IMP metabolic process" "6/743" "13/17381" 7.92966134965725e-06 7.64171275316132e-05 4.58541624649395e-05 "AMPD3/AMPD1/ATIC/AMPD2/ADSL/ADSS" 6 +"GO:0032868" "GO:0032868" "response to insulin" "27/743" "248/17381" 8.31154113906184e-06 7.99483743394889e-05 4.79730901198052e-05 "ATP6V1C1/ADM/CDK4/AKT2/AGT/AKT1/ATP6V1B2/ATP6V0A1/APC/AGRP/ATP6V1B1/ATP6V1A/CAT/ATP6AP1/ATP6V1G2/APRT/ATP6V0C/ATP6V0B/ATP6V1E1/CEACAM1/CCND3/PARP1/CAV2/ZFP36L1/APOBEC1/AHSG/AANAT" 27 +"GO:0042326" "GO:0042326" "negative regulation of phosphorylation" "41/743" "462/17381" 8.33668064909662e-06 8.00414143953155e-05 4.80289188845524e-05 "BDKRB2/CDKN1B/CALM1/BDKRB1/CALM3/CDKN2D/CCNB1/RHOH/AKT1/APOE/ARRB1/APC/CAV3/ADAR/CALM2/CBLB/BGN/BAX/ACTN3/ADARB1/BMP7/CDKN2B/CDKN1A/ARRB2/CAV1/ATF3/CBFA2T3/CEACAM1/AMBP/ADORA2A/CDKN1C/CASP3/CDKN2A/AHSG/LDLRAD4/BMP4/CDKN2C/ABL1/CBL/BAK1/ANGPT1" 41 +"GO:0051817" "GO:0051817" "modification of morphology or physiology of other organism involved in symbiotic interaction" "16/743" "104/17381" 8.35325328606889e-06 8.00520106581602e-05 4.80352771810979e-05 "SLC25A6/ANXA2/CD4/ALB/AZU1/APOE/BAD/CCNT1/CAMP/CASP8/C9/AQP1/CAV2/ARG1/BCL2L1/APCS" 16 +"GO:0038034" "GO:0038034" "signal transduction in absence of ligand" "13/743" "71/17381" 8.40446344703657e-06 8.02400435787156e-05 4.81481064952374e-05 "BCL2A1/CASP9/FAS/BCL2L2/AKT1/BAD/BOK/CASP2/BAX/BCL2/CASP3/BCL2L1/BAK1" 13 +"GO:0097192" "GO:0097192" "extrinsic apoptotic signaling pathway in absence of ligand" "13/743" "71/17381" 8.40446344703657e-06 8.02400435787156e-05 4.81481064952374e-05 "BCL2A1/CASP9/FAS/BCL2L2/AKT1/BAD/BOK/CASP2/BAX/BCL2/CASP3/BCL2L1/BAK1" 13 +"GO:2001233" "GO:2001233" "regulation of apoptotic signaling pathway" "36/743" "383/17381" 8.44533598710131e-06 8.02400435787156e-05 4.81481064952374e-05 "BDKRB2/BID/FAS/CD74/AGT/CDKN2D/BCL2L2/AKT1/BAD/AR/SLC25A5/BOK/CASP2/BAX/FASLG/ARRB2/CASP8/CAV1/BCL2/ATF3/BMPR1B/BIK/AGTR2/ACVR1/PARP1/ADORA2A/BMP5/BRCA1/AVP/CD44/APAF1/BCL2L1/BMP4/BNIP3/PTTG1IP/BAK1" 36 +"GO:0036296" "GO:0036296" "response to increased oxygen levels" "8/743" "26/17381" 8.45040072471498e-06 8.02400435787156e-05 4.81481064952374e-05 "CDK4/FAS/ATP6V1A/CAT/ATP6AP1/CDKN1A/CAV1/BNIP3" 8 +"GO:0046688" "GO:0046688" "response to copper ion" "8/743" "26/17381" 8.45040072471498e-06 8.02400435787156e-05 4.81481064952374e-05 "AQP2/CDK1/AOC1/ATP7A/ATP5D/AQP1/ATP7B/AANAT" 8 +"GO:0007178" "GO:0007178" "transmembrane receptor protein serine/threonine kinase signaling pathway" "32/743" "322/17381" 8.61405206112806e-06 8.13740313041703e-05 4.88285567957899e-05 "BMP2/ACVR2B/ACVRL1/BMPR1A/ACVR1B/RUNX2/BMP8B/CAV3/CDH5/AFP/BMPR2/AMH/AMHR2/BMP7/CDKN2B/ARRB2/XIAP/CAV1/BMPR1B/RHOA/ACVR1/PARP1/BMP6/CAV2/CDKN1C/BMP5/ACVR2A/LDLRAD4/BMP4/ABL1/CBL/BMP3" 32 +"GO:0006839" "GO:0006839" "mitochondrial transport" "31/743" "307/17381" 8.61699887047059e-06 8.13740313041703e-05 4.88285567957899e-05 "BNIP3L/ATP5F1/SLC25A6/BID/ATP5C1/ATP5G1/ATP5E/TSPO/BAD/SLC25A5/ACACA/BOK/ATP5I/ATP5O/BAX/ATP5G3/ACTL6A/ATP5D/ATP5J/CASP8/BCL2/ACACB/ATP5G2/ATP5B/ATP5A1/BCL2L1/BNIP3/CAMK2A/SLC25A4/BAK1/SLC25A20" 31 +"GO:1901342" "GO:1901342" "regulation of vasculature development" "31/743" "307/17381" 8.61699887047059e-06 8.13740313041703e-05 4.88285567957899e-05 "APLNR/KLK3/ADM/ACVRL1/C6/AGT/ADGRB3/C3AR1/RUNX1/CD34/ADGRB1/C5/ADGRB2/BTG1/KRIT1/ALOX12/FASLG/BMP7/ANXA3/CD40/C3/APOH/RHOA/CEACAM1/AQP1/RHOB/C5AR1/ANGPT2/BRCA1/BMP4/ABL1" 31 +"GO:0090132" "GO:0090132" "epithelium migration" "28/743" "263/17381" 8.69599952954181e-06 8.19704873686318e-05 4.91864607653117e-05 "ACVRL1/SCARB1/AGT/AKT1/APOE/ADGRB1/BMPR2/KRIT1/APOA1/ALOX12/ANXA3/AAMP/CD40/APOH/RHOA/AGTR2/CEACAM1/CALR/AQP1/ARSB/RHOB/ANGPT2/ATP5B/CDH13/ATP5A1/BMP4/ABL1/ANGPT1" 28 +"GO:0032411" "GO:0032411" "positive regulation of transporter activity" "15/743" "93/17381" 8.82832051634795e-06 8.30664703129102e-05 4.98441062645482e-05 "CASQ1/ANXA2/CALM1/ADRB2/CALM3/ATP1B3/ACTN2/ATP1B2/CALM2/CACNA2D1/ANK3/ATP1B1/ACTN4/ANK2/CACNB2" 15 +"GO:0014808" "GO:0014808" "release of sequestered calcium ion into cytosol by sarcoplasmic reticulum" "9/743" "34/17381" 9.09331221181465e-06 8.54045203196748e-05 5.12470551625814e-05 "CASQ1/CALM1/CACNA1C/CALM3/CAMK2D/CALM2/ATP1A2/CASQ2/ANK2" 9 +"GO:0032355" "GO:0032355" "response to estradiol" "18/743" "129/17381" 9.48919615777332e-06 8.88003437910975e-05 5.32847219290593e-05 "ANXA1/CDKN1B/BID/CD4/CASP9/AGT/BAD/AREG/ADCYAP1R1/CAT/BMP7/CASP8/CD38/CALR/CASP3/CCNA2/APOB/CCND1" 18 +"GO:0045580" "GO:0045580" "regulation of T cell differentiation" "18/743" "129/17381" 9.48919615777332e-06 8.88003437910975e-05 5.32847219290593e-05 "ANXA1/CD74/RUNX1/CD80/BAD/CD27/PRDM1/ADA/BRAF/BCL6/CBFB/CD2/CAMK4/CD28/ADAM8/BMP4/CD86/ABL1" 18 +"GO:1903532" "GO:1903532" "positive regulation of secretion by cell" "34/743" "355/17381" 1.0067194814435e-05 9.40392295391714e-05 5.64283197845015e-05 "CASP1/AVPR1A/AGT/ARRB1/ARF1/BAD/CASP5/CD34/AP1G1/C5/BLK/CASR/FOXL2/ANG/ACHE/ATP6AP1/ADORA2B/ABAT/CD38/CCK/APBB1/CD2/AGTR2/CD14/BMP6/ADCYAP1/ADORA2A/GRK2/CDK5/AVP/CD58/ADAM8/ABL1/ALOX15B" 34 +"GO:0019835" "GO:0019835" "cytolysis" "10/743" "43/17381" 1.02023619176276e-05 9.46186790747723e-05 5.67760189718949e-05 "C8A/C8G/C6/ALB/BAD/C5/C8B/C7/C9/BAK1" 10 +"GO:0045744" "GO:0045744" "negative regulation of G-protein coupled receptor protein signaling pathway" "10/743" "43/17381" 1.02023619176276e-05 9.46186790747723e-05 5.67760189718949e-05 "APLNR/ADM/ADRB2/ARRB1/ATP2B4/ADA/ADRA2A/ARRB2/BICD1/GRK2" 10 +"GO:0098659" "GO:0098659" "inorganic cation import across plasma membrane" "10/743" "43/17381" 1.02023619176276e-05 9.46186790747723e-05 5.67760189718949e-05 "ATP2B4/ATP1A1/CACNA2D1/CALCR/FXYD2/ATP1A2/ATP1B1/HCN2/ARHGAP1/B2M" 10 +"GO:0099587" "GO:0099587" "inorganic ion import across plasma membrane" "10/743" "43/17381" 1.02023619176276e-05 9.46186790747723e-05 5.67760189718949e-05 "ATP2B4/ATP1A1/CACNA2D1/CALCR/FXYD2/ATP1A2/ATP1B1/HCN2/ARHGAP1/B2M" 10 +"GO:0050864" "GO:0050864" "regulation of B cell activation" "20/743" "155/17381" 1.02757512287293e-05 9.49445875553835e-05 5.69715806332838e-05 "FAS/CD74/BTK/CD81/BAD/CD27/PRDM1/ADA/CDKN1A/ZFP36L2/BCL2/CD40/BCL6/CD38/ATM/BST1/ZFP36L1/AHR/CASP3/CD28" 20 +"GO:0002028" "GO:0002028" "regulation of sodium ion transport" "14/743" "83/17381" 1.02925436944097e-05 9.49445875553835e-05 5.69715806332838e-05 "ADRB2/ATP1B3/AKT1/ARF1/ATP2B4/ATP1B2/ATP1A1/CAMK2D/CAV3/FXYD2/ATP1A2/ANK3/ATP1B1/ACTN4" 14 +"GO:0032414" "GO:0032414" "positive regulation of ion transmembrane transporter activity" "14/743" "83/17381" 1.02925436944097e-05 9.49445875553835e-05 5.69715806332838e-05 "CASQ1/CALM1/ADRB2/CALM3/ATP1B3/ACTN2/ATP1B2/CALM2/CACNA2D1/ANK3/ATP1B1/ACTN4/ANK2/CACNB2" 14 +"GO:0072593" "GO:0072593" "reactive oxygen species metabolic process" "27/743" "251/17381" 1.03739328599776e-05 9.55250935060218e-05 5.73199137234202e-05 "BIRC2/ARF4/AIF1/ARG2/AGT/AKT1/ACP5/TSPO/APOA4/CD34/ADGRB1/ATP2B4/BCR/CD36/ATP7A/AGTR1/CAT/ALOX12/BMP7/CDKN1A/CAV1/BCL2/ASS1/AGTR2/BST1/BRCA1/BNIP3" 27 +"GO:0032869" "GO:0032869" "cellular response to insulin stimulus" "23/743" "195/17381" 1.04368216429312e-05 9.59334849061614e-05 5.75649693309283e-05 "ATP6V1C1/CDK4/AKT2/AGT/AKT1/ATP6V1B2/ATP6V0A1/APC/ATP6V1B1/ATP6V1A/ATP6AP1/ATP6V1G2/APRT/ATP6V0C/ATP6V0B/ATP6V1E1/CEACAM1/CCND3/PARP1/CAV2/ZFP36L1/APOBEC1/AHSG" 23 +"GO:0002065" "GO:0002065" "columnar/cuboidal epithelial cell differentiation" "16/743" "106/17381" 1.07196072230133e-05 9.83580981898829e-05 5.90198605970312e-05 "BMP2/KLF5/CDK6/BAD/CDH2/ASCL1/PRDM1/CDKN1A/ATOH1/ARNTL/BMP6/BMP5/NKX3-2/JAG1/BMP4/ABL1" 16 +"GO:0010575" "GO:0010575" "positive regulation of vascular endothelial growth factor production" "8/743" "27/17381" 1.156064859038e-05 0.000105803753148623 6.34876321969869e-05 "C3AR1/ARNT/C5/ADORA2B/C3/C5AR1/BRCA1/ATF4" 8 +"GO:0009612" "GO:0009612" "response to mechanical stimulus" "24/743" "210/17381" 1.15719660448542e-05 0.000105803753148623 6.34876321969869e-05 "CASP1/BDKRB1/FAS/AGT/CCNB1/AKT1/ASIC2/ACTA1/BAD/CASP5/BGLAP/ATP1A1/CASP2/CAV3/ATP1A2/TNFRSF8/CASP8/CD40/AQP1/BMP6/ANGPT2/ASNS/BNIP3/BAK1" 24 +"GO:0043277" "GO:0043277" "apoptotic cell clearance" "9/743" "35/17381" 1.17799119017243e-05 0.000107137160090375 6.42877441681376e-05 "C2/AXL/SCARB1/ADGRB1/CD36/ALOX15/C3/C4B/C4A" 9 +"GO:0090207" "GO:0090207" "regulation of triglyceride metabolic process" "9/743" "35/17381" 1.17799119017243e-05 0.000107137160090375 6.42877441681376e-05 "APOC2/APOC3/SCARB1/APOE/APOA4/AADAC/APOA1/C3/APOBEC1" 9 +"GO:1903523" "GO:1903523" "negative regulation of blood circulation" "9/743" "35/17381" 1.17799119017243e-05 0.000107137160090375 6.42877441681376e-05 "ADM/ATP2A2/ADRA1A/ATP1A1/BMPR2/ATP1A2/AGTR2/GRK2/ADORA1" 9 +"GO:0032102" "GO:0032102" "negative regulation of response to external stimulus" "29/743" "282/17381" 1.18026944944908e-05 0.000107156042121035 6.4299074346718e-05 "BBS2/ANXA2/AIF1/ARG2/AGER/ACP5/APOE/CD34/ABR/BCR/CD9/C5/BBS4/PRDM1/APOA1/ALOX12/ADA/ABAT/APOH/CCK/CEACAM1/ADCYAP1/ADORA2A/ANGPT2/APOD/APCS/C1QBP/SERPING1/ADORA1" 29 +"GO:0046068" "GO:0046068" "cGMP metabolic process" "11/743" "53/17381" 1.19228725658684e-05 0.000108057557843028 6.48400296235814e-05 "ADCY1/ADCY6/APOE/ADCY5/ADCY9/ADCY7/ADORA2B/AQP1/ADCY8/ADCY3/ADCY2" 11 +"GO:0006525" "GO:0006525" "arginine metabolic process" "7/743" "20/17381" 1.20649742161775e-05 0.000108584767945597 6.51563824946883e-05 "ASL/CAD/ARG2/ATP2B4/ASS1/ARG1/ART4" 7 +"GO:0009083" "GO:0009083" "branched-chain amino acid catabolic process" "7/743" "20/17381" 1.20649742161775e-05 0.000108584767945597 6.51563824946883e-05 "BCAT1/ACAT1/AUH/ACADSB/BCKDHA/BCAT2/BCKDHB" 7 +"GO:0009651" "GO:0009651" "response to salt stress" "7/743" "20/17381" 1.20649742161775e-05 0.000108584767945597 6.51563824946883e-05 "BDKRB2/ANXA7/CAPN3/BAX/AQP1/ZFP36L1/AVP" 7 +"GO:0045603" "GO:0045603" "positive regulation of endothelial cell differentiation" "7/743" "20/17381" 1.20649742161775e-05 0.000108584767945597 6.51563824946883e-05 "ACVRL1/ADD1/CDH5/BTG1/ALOX12/BMP6/BMP4" 7 +"GO:0071706" "GO:0071706" "tumor necrosis factor superfamily cytokine production" "17/743" "119/17381" 1.2159446125487e-05 0.000109245023783672 6.55525695727096e-05 "APP/AXL/BPI/ARG2/AZU1/ACP5/TSPO/CD34/CD36/TNFRSF8/ARRB2/BCL3/CD2/CD14/ADAM8/CD86/ANGPT1" 17 +"GO:0015909" "GO:0015909" "long-chain fatty acid transport" "12/743" "63/17381" 1.22222835997725e-05 0.000109619267987561 6.5777135126022e-05 "ANXA1/BDKRB2/AKT2/AKT1/APOE/ACACA/ABCD2/CD36/ACACB/PLIN2/ABCD1/SLC25A20" 12 +"GO:0030099" "GO:0030099" "myeloid cell differentiation" "36/743" "390/17381" 1.25920019247332e-05 0.000112739809620232 6.76496187906809e-05 "APP/ANXA2/ALAS2/CD4/CASP9/CDK6/FAS/ACTN1/CD74/ACVR1B/RUNX1/ARNT/BGLAP/ADD1/ADAR/CDC42/ATP6AP1/CDKN2B/CASP8/BCL6/CBFB/CBFA2T3/CEACAM1/PARP1/ZFP36L1/CAMK4/CDKN1C/ACVR2A/CASP3/C1QC/CA2/JAG1/APCS/BMP4/CD86/B2M" 36 +"GO:0015701" "GO:0015701" "bicarbonate transport" "10/743" "44/17381" 1.27018073535117e-05 0.000113526516501595 6.81216829249334e-05 "CA9/CA6/CA3/CA4/AQP1/CA12/CA2/CA7/CA1/CA5A" 10 +"GO:0051591" "GO:0051591" "response to cAMP" "15/743" "96/17381" 1.31264459063572e-05 0.000117119582009308 7.02777049432917e-05 "CDO1/APP/BIRC2/AQP8/BSG/AREG/AQP9/BRAF/HCN2/AQP1/ZFP36L1/ALDH3A1/APEX1/AANAT/AGXT" 15 +"GO:0050900" "GO:0050900" "leukocyte migration" "41/743" "471/17381" 1.32251927488903e-05 0.000117797542987104 7.06845160054832e-05 "ANXA1/APP/AIF1/BDKRB1/CD74/ATP1B3/CALCA/CXCR5/CD47/AZU1/C3AR1/CD34/ATP1B2/ABR/BCR/C5/BSG/ADD2/AIRE/CDC42/ADA/CAV1/RHOA/ATP1B1/CD2/CEACAM1/CALR/BST1/C5AR1/ANGPT2/BMP5/APOD/CD48/CD44/CD58/APOB/ADAM8/ADAM10/C1QBP/ANGPT1/ADORA1" 41 +"GO:0043173" "GO:0043173" "nucleotide salvage" "6/743" "14/17381" 1.3375035431809e-05 0.000118927505772528 7.13625511373421e-05 "ADK/AMPD3/AMPD1/ADA/APRT/AMPD2" 6 +"GO:0002685" "GO:0002685" "regulation of leukocyte migration" "21/743" "171/17381" 1.34870141745116e-05 0.000119717492886959 7.18365835782416e-05 "ANXA1/APP/AIF1/BDKRB1/CD74/C3AR1/ABR/BCR/C5/AIRE/ADA/RHOA/CALR/BST1/C5AR1/BMP5/APOD/ADAM8/ADAM10/C1QBP/ADORA1" 21 +"GO:0030168" "GO:0030168" "platelet activation" "20/743" "158/17381" 1.37128928919646e-05 0.00012151407656835 7.29146251465311e-05 "AXL/AKT1/APOE/ARRB1/ADRA2B/CD9/ADRA2C/ACTB/ALOX12/RHOG/ADRA2A/ACTG1/ARRB2/ABAT/CD40/RHOA/CEACAM1/ENTPD2/RHOB/CD40LG" 20 +"GO:0051146" "GO:0051146" "striated muscle cell differentiation" "28/743" "270/17381" 1.42306715879178e-05 0.000125886710200811 7.55384276821547e-05 "BMP2/CASQ1/CDK1/AVPR1A/AGT/CCNB1/AKT1/ADGRB3/ACTA1/ACTN2/ADGRB1/CDH2/BCL9/CAV3/CAPN3/BDNF/ACTG1/ARRB2/BCL2/ACTC1/AGTR2/ACVR1/CALR/CASQ2/CAV2/CAPN2/CD53/BMP4" 28 +"GO:0070228" "GO:0070228" "regulation of lymphocyte apoptotic process" "11/743" "54/17381" 1.44008872471541e-05 0.000127099086834547 7.62659153138905e-05 "CD3G/ARG2/FAS/CD74/BTK/CD27/BAX/ADA/BCL6/ADAM8/BMP4" 11 +"GO:0006909" "GO:0006909" "phagocytosis" "31/743" "315/17381" 1.44168432795902e-05 0.000127099086834547 7.62659153138905e-05 "ANXA1/C4BPA/C2/AIF1/AXL/CD3G/SCARB1/CD47/AZU1/CD247/ADGRB1/ABR/BCR/ABCA1/CD36/CDC42/ACTB/ANXA3/ALOX15/ACTG1/C4BPB/C3/CD14/CALR/ADORA2A/C4B/C4A/AHSG/ANXA11/ABL1/ADORA1" 31 +"GO:0008585" "GO:0008585" "female gonad development" "15/743" "97/17381" 1.49243084153476e-05 0.000131349142941197 7.88161651007436e-05 "BRCA2/ARRB1/CASP2/AFP/AMH/FOXL2/ANG/BAX/AMHR2/ARRB2/BCL2/BMPR1B/ATM/ADCYAP1/BCL2L1" 15 +"GO:0008286" "GO:0008286" "insulin receptor signaling pathway" "17/743" "121/17381" 1.52194997865451e-05 0.000133719713744263 8.02386281302975e-05 "ATP6V1C1/CDK4/AKT2/AKT1/ATP6V1B2/ATP6V0A1/APC/ATP6V1B1/ATP6V1A/ATP6AP1/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1/CCND3/CAV2/AHSG" 17 +"GO:0031589" "GO:0031589" "cell-substrate adhesion" "31/743" "316/17381" 1.53506495983799e-05 0.000134643409612908 8.07928926230521e-05 "AXL/ACVRL1/DDR1/CDK6/ACTN1/CD34/ACTN2/CD36/CDC42/ARL2/ACTN3/APOA1/ALOX15/BCL2/BRAF/BCL6/RHOA/CD63/ARHGAP6/CALR/BST1/ANGPT2/ACTN4/APOD/CDK5/CDKN2A/CDH13/CD44/C1QBP/ABL1/ANGPT1" 31 +"GO:0010107" "GO:0010107" "potassium ion import" "8/743" "28/17381" 1.55816485055181e-05 0.000136438292751364 8.18699137791046e-05 "ATP1B3/ATP1A3/ATP1B2/ATP1A1/FXYD2/ATP1A2/ATP1B1/HCN2" 8 +"GO:0090559" "GO:0090559" "regulation of membrane permeability" "14/743" "86/17381" 1.56878391948788e-05 0.000136877167194111 8.21332607622942e-05 "BNIP3L/SLC25A6/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BCL2L1/BNIP3/CAMK2A/SLC25A4/BAK1" 14 +"GO:0051353" "GO:0051353" "positive regulation of oxidoreductase activity" "10/743" "45/17381" 1.57111183214111e-05 0.000136877167194111 8.21332607622942e-05 "ABL2/SCARB1/AGT/AKT1/CDH3/APOE/ATP7A/AGTR1/AGTR2/ABL1" 10 +"GO:0090199" "GO:0090199" "regulation of release of cytochrome c from mitochondria" "10/743" "45/17381" 1.57111183214111e-05 0.000136877167194111 8.21332607622942e-05 "BID/AKT1/BAD/BAX/ARRB2/BIK/AVP/BCL2L1/BNIP3/BAK1" 10 +"GO:0010952" "GO:0010952" "positive regulation of peptidase activity" "21/743" "173/17381" 1.6136415755293e-05 0.00014034613703133 8.42148190678716e-05 "APP/CASP1/BID/CASP9/FAS/ASPH/ARRB1/BAD/BOK/CASP2/FOXL2/BAX/ALOX12/FASLG/CASP8/CAV1/CCK/CASP7/CASP3/APAF1/BAK1" 21 +"GO:0045766" "GO:0045766" "positive regulation of angiogenesis" "19/743" "147/17381" 1.65909390949001e-05 0.000144057231235081 8.64416643058202e-05 "APLNR/ADM/ACVRL1/C6/C3AR1/RUNX1/CD34/C5/BTG1/ALOX12/ANXA3/CD40/C3/AQP1/RHOB/C5AR1/ANGPT2/BRCA1/ABL1" 19 +"GO:0016101" "GO:0016101" "diterpenoid metabolic process" "15/743" "98/17381" 1.69369260705004e-05 0.000146815062671423 8.80965034082275e-05 "APOC2/APOC3/APOE/APOA4/ALDH3A2/OPN1SW/APOA1/ADH7/ADH5/ADH4/ALDH1A1/ALDH1A3/APOA2/ABCA4/APOB" 15 +"GO:0072329" "GO:0072329" "monocarboxylic acid catabolic process" "17/743" "122/17381" 1.69930001308227e-05 0.000147054808824427 8.82403632915452e-05 "ACOX1/AKT2/ACAT1/ACAT2/AKT1/AUH/ABCD2/ACADM/ALDH3A2/ABAT/ACADVL/ACADL/ACACB/ACAA1/ACADS/ABCD1/AGXT" 17 +"GO:0010332" "GO:0010332" "response to gamma radiation" "11/743" "55/17381" 1.73136079305077e-05 0.000149579167012316 8.97551065723535e-05 "ATR/BRCA2/BAX/CDKN1A/BCL2/ATM/PARP1/APOBEC1/BCL2L1/CBL/BAK1" 11 +"GO:0040013" "GO:0040013" "negative regulation of locomotion" "30/743" "303/17381" 1.75745737075155e-05 0.000151580698227321 9.09561270827558e-05 "AIF1/ACVRL1/BMPR1A/APOE/ADGRB1/ABR/ADORA3/BCR/C5/KRIT1/ADA/ADARB1/ARHGAP4/BCL2/BRAF/APOH/RHOA/AGTR2/CALR/RHOB/BST2/ADORA2A/ANGPT2/BMP5/APOD/APEX1/LDLRAD4/ARHGDIB/ALOX15B/ADORA1" 30 +"GO:0050866" "GO:0050866" "negative regulation of cell activation" "21/743" "174/17381" 1.76293438149064e-05 0.000151800090253146 9.10877734547226e-05 "ANXA1/AXL/BPI/ARG2/FAS/CD74/APOE/BTK/ABR/BCR/CD9/PRDM1/ALOX12/ABAT/BCL6/CEACAM1/ATM/ADORA2A/CASP3/ARG1/BMP4" 21 +"GO:0006813" "GO:0006813" "potassium ion transport" "26/743" "244/17381" 1.779025065578e-05 0.000152931141434654 9.17664616795787e-05 "ATP12A/CDKN1B/ATP1B3/ATP1A3/ACTN2/ATP1B2/ATP1A1/ATP4B/CAV3/FXYD2/CDK2/ADRA2A/ATP1A2/ATP4A/CAV1/ANK3/CACNA1D/ATP1A4/ATP1B1/HCN2/AQP1/CASQ2/ADCYAP1/ANK2/ATF4/ADORA1" 26 +"GO:0006520" "GO:0006520" "cellular amino acid metabolic process" "34/743" "365/17381" 1.80745478857955e-05 0.000155117388572125 9.3078321136592e-05 "CDO1/AARS/BCAT1/ASL/CAD/KYAT1/ALDH7A1/AHCY/BAAT/ARG2/ACAT1/ATP2B4/AMT/AUH/ASPA/ATP7A/ACADSB/BLMH/CBS/CARS/BCKDHA/ABAT/BCAT2/ASS1/ACY1/ASNS/ARG1/ART4/ADSS/BCKDHB/ATF4/BHMT/BPHL/AGXT" 34 +"GO:0031295" "GO:0031295" "T cell costimulation" "13/743" "76/17381" 1.81450589669987e-05 0.000155464702242083 9.32867270000805e-05 "CD3G/CD4/AKT1/CD80/CD247/CD3E/CD3D/CDC42/CAV1/CD5/CD28/CD40LG/CD86" 13 +"GO:0030900" "GO:0030900" "forebrain development" "34/743" "366/17381" 1.91339226345101e-05 0.00016360744808224 9.81727885771894e-05 "APP/BMP2/BCL2A1/BBS2/ATRX/AXL/AVPR1A/CDK6/BMPR1A/ALK/BAD/ATP1A3/NR0B1/CDH2/ATP2B4/CCKAR/ASCL1/BBS4/ATP7A/ATIC/BAX/ANXA3/ATOH1/ALDH1A3/AQP1/ADCYAP1/KIF1A/CDH1/CASP3/CDK5/AVPR2/APAF1/BMP4/BNIP3" 34 +"GO:0030282" "GO:0030282" "bone mineralization" "15/743" "99/17381" 1.91860745301369e-05 0.00016360744808224 9.81727885771894e-05 "BMP2/ADRB2/ACVR2B/BMPR1A/BGLAP/ASGR2/BMPR2/BMP7/ALOX15/BMPR1B/ACVR1/BMP6/ACVR2A/AHSG/BMP4" 15 +"GO:0045601" "GO:0045601" "regulation of endothelial cell differentiation" "9/743" "37/17381" 1.92218992142999e-05 0.00016360744808224 9.81727885771894e-05 "ACVRL1/ADD1/CDH5/BTG1/ALOX12/CEACAM1/BMP6/JAG1/BMP4" 9 +"GO:0070266" "GO:0070266" "necroptotic process" "9/743" "37/17381" 1.92218992142999e-05 0.00016360744808224 9.81727885771894e-05 "BIRC2/FAS/BOK/FASLG/CASP8/CAV1/CD14/BIRC3/SLC25A4" 9 +"GO:0072132" "GO:0072132" "mesenchyme morphogenesis" "10/743" "46/17381" 1.93137075865266e-05 0.000164118943777135 9.84797120045866e-05 "BMP2/ACVRL1/BMPR1A/ACTA2/ACTA1/BMP7/ACTG2/ACTC1/ACVR1/BMP5" 10 +"GO:0010810" "GO:0010810" "regulation of cell-substrate adhesion" "22/743" "189/17381" 1.9898740468001e-05 0.000168813085117878 0.000101296435514414 "ACVRL1/DDR1/CDK6/CD36/CDC42/ARL2/APOA1/ALOX15/BCL2/BRAF/BCL6/RHOA/ARHGAP6/CALR/BST1/ANGPT2/ACTN4/APOD/CDKN2A/CDH13/C1QBP/ABL1" 22 +"GO:0016042" "GO:0016042" "lipid catabolic process" "30/743" "305/17381" 1.99447134473205e-05 0.000168926173633198 0.000101364294374357 "APOC2/STS/APOC3/CDK4/SCARB1/ACOX1/AKT2/ACAT1/ACAT2/AKT1/APOE/APOA4/AUH/ABCD2/ACADM/AADAC/ALDH3A2/APOA1/ADRA2A/ACADVL/ACADL/ACACB/APOA2/ACAA1/APOC1/DAGLA/ACADS/APOB/ABCD1/ADORA1" 30 +"GO:0010212" "GO:0010212" "response to ionizing radiation" "19/743" "149/17381" 2.01393551813601e-05 0.000170296018077677 0.000102186270700056 "ANXA1/ATR/BRCA2/CCND2/ALAD/BAX/CDKN1A/BCL2/BLM/ATM/RHOB/PARP1/APOBEC1/CASP3/BRCA1/BCL2L1/CCND1/CBL/BAK1" 19 +"GO:0061036" "GO:0061036" "positive regulation of cartilage development" "8/743" "29/17381" 2.07158982290829e-05 0.000174662108080338 0.000104806146725044 "BMP2/ACVRL1/RUNX2/BMPR2/BMP1/BMPR1B/BMP6/BMP4" 8 +"GO:0046503" "GO:0046503" "glycerolipid catabolic process" "11/743" "56/17381" 2.07231950456671e-05 0.000174662108080338 0.000104806146725044 "APOC2/APOC3/SCARB1/APOE/APOA4/AADAC/APOA1/APOA2/APOC1/DAGLA/APOB" 11 +"GO:0034380" "GO:0034380" "high-density lipoprotein particle assembly" "6/743" "15/17381" 2.14861529011253e-05 0.00018050461244046 0.000108311946442788 "APOE/APOA4/ABCA1/APOA1/BMP1/APOA2" 6 +"GO:0061577" "GO:0061577" "calcium ion transmembrane transport via high voltage-gated calcium channel" "6/743" "15/17381" 2.14861529011253e-05 0.00018050461244046 0.000108311946442788 "CACNA1C/CAMK2D/CACNA2D1/CACNB1/CACNB2/CACNB3" 6 +"GO:0008406" "GO:0008406" "gonad development" "24/743" "218/17381" 2.16652969843308e-05 0.000181378492362915 0.000108836318834599 "BRCA2/ATRX/BCL2L2/ARRB1/AR/NR0B1/BOK/CASP2/AFP/AMH/FOXL2/ANG/BAX/AMHR2/ARRB2/BCL2/BMPR1B/BIK/ATM/ADCYAP1/ACVR2A/BCL2L1/CCND1/CBL" 24 +"GO:0007569" "GO:0007569" "cell aging" "15/743" "100/17381" 2.16953211154868e-05 0.000181378492362915 0.000108836318834599 "ATR/BRCA2/CDK1/CDK6/ARG2/BMPR1A/BGLAP/CDKN1A/BCL2/BCL6/ATM/CALR/ARNTL/CDKN2A/ABL1" 15 +"GO:0009062" "GO:0009062" "fatty acid catabolic process" "15/743" "100/17381" 2.16953211154868e-05 0.000181378492362915 0.000108836318834599 "ACOX1/AKT2/ACAT1/ACAT2/AKT1/AUH/ABCD2/ACADM/ALDH3A2/ACADVL/ACADL/ACACB/ACAA1/ACADS/ABCD1" 15 +"GO:0051209" "GO:0051209" "release of sequestered calcium ion into cytosol" "16/743" "112/17381" 2.17952550336991e-05 0.000181627125280826 0.000108985511228769 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CALM3/CAMK2D/CALM2/CAPN3/BAX/CD19/ATP1A2/FASLG/CASQ2/ANK2/ABL1" 16 +"GO:0051283" "GO:0051283" "negative regulation of sequestering of calcium ion" "16/743" "112/17381" 2.17952550336991e-05 0.000181627125280826 0.000108985511228769 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CALM3/CAMK2D/CALM2/CAPN3/BAX/CD19/ATP1A2/FASLG/CASQ2/ANK2/ABL1" 16 +"GO:0048145" "GO:0048145" "regulation of fibroblast proliferation" "14/743" "89/17381" 2.34371254586481e-05 0.000194995376605312 0.000117007141822664 "ANXA2/CDK4/CDK6/CD74/AGT/CCNB1/CDC6/BAX/CDKN1A/BTC/AGTR2/BMI1/AQP1/CCNA2" 14 +"GO:0042440" "GO:0042440" "pigment metabolic process" "12/743" "67/17381" 2.34864938536193e-05 0.000195092464995955 0.000117065399794165 "BLVRB/ALAS2/ALAS1/CDH3/TSPO/BLVRA/ALAD/ADA/APRT/BCL2/AMBP/ASIP" 12 +"GO:0033344" "GO:0033344" "cholesterol efflux" "10/743" "47/17381" 2.36032149900058e-05 0.000195434620117248 0.000117270710266134 "APOC2/APOC3/SCARB1/APOE/APOA4/ABCA1/APOA1/APOA2/APOC1/APOB" 10 +"GO:0045058" "GO:0045058" "T cell selection" "10/743" "47/17381" 2.36032149900058e-05 0.000195434620117248 0.000117270710266134 "CD4/FAS/CD74/CD3E/AIRE/CD3D/BCL2/BRAF/CD28/CD1D" 10 +"GO:0001936" "GO:0001936" "regulation of endothelial cell proliferation" "16/743" "113/17381" 2.44017262585608e-05 0.000201401807636447 0.000120851326219684 "BMP2/ACVRL1/AKT1/APOE/ARNT/BMPR2/KRIT1/ANG/CAV1/APOH/BMP6/CAV2/CDH13/ARG1/ATP5A1/BMP4" 16 +"GO:0051282" "GO:0051282" "regulation of sequestering of calcium ion" "16/743" "113/17381" 2.44017262585608e-05 0.000201401807636447 0.000120851326219684 "CASQ1/CALM1/APLNR/CACNA1C/BDKRB1/CALM3/CAMK2D/CALM2/CAPN3/BAX/CD19/ATP1A2/FASLG/CASQ2/ANK2/ABL1" 16 +"GO:0033559" "GO:0033559" "unsaturated fatty acid metabolic process" "15/743" "101/17381" 2.44901339915246e-05 0.000201809623258184 0.000121096036330871 "ANXA1/AVPR1A/ACOX1/CD74/ALOX12/ALOX15/CBR1/ACAA1/ALOX12B/AVP/ALOX5/DAGLA/ALOX5AP/ABCD1/ALOX15B" 15 +"GO:0032469" "GO:0032469" "endoplasmic reticulum calcium ion homeostasis" "7/743" "22/17381" 2.46267001749713e-05 0.000201920004880363 0.000121162270917278 "APP/ATP2A2/CAMK2D/BAX/BCL2/ATP2A1/BAK1" 7 +"GO:0050995" "GO:0050995" "negative regulation of lipid catabolic process" "7/743" "22/17381" 2.46267001749713e-05 0.000201920004880363 0.000121162270917278 "APOC3/AKT1/ADRA2A/ACACB/APOA2/APOC1/ADORA1" 7 +"GO:0050996" "GO:0050996" "positive regulation of lipid catabolic process" "7/743" "22/17381" 2.46267001749713e-05 0.000201920004880363 0.000121162270917278 "APOC2/AKT2/APOA4/ABCD2/AADAC/APOA1/APOA2" 7 +"GO:0001541" "GO:0001541" "ovarian follicle development" "11/743" "57/17381" 2.46986208868154e-05 0.000201920004880363 0.000121162270917278 "ARRB1/AMH/FOXL2/ANG/BAX/ARRB2/BCL2/BMPR1B/ATM/ADCYAP1/BCL2L1" 11 +"GO:0098739" "GO:0098739" "import across plasma membrane" "11/743" "57/17381" 2.46986208868154e-05 0.000201920004880363 0.000121162270917278 "AGT/ATP2B4/ATP1A1/CACNA2D1/CALCR/FXYD2/ATP1A2/ATP1B1/HCN2/ARHGAP1/B2M" 11 +"GO:0007589" "GO:0007589" "body fluid secretion" "14/743" "90/17381" 2.66806026255525e-05 0.000217436407223991 0.000130472901359934 "CDO1/ANXA2/DDR1/SERPINC1/ATP7A/ADA/APRT/CAV1/AQP1/ALOX12B/ATP7B/AQP5/CCND1/ADORA1" 14 +"GO:0048144" "GO:0048144" "fibroblast proliferation" "14/743" "90/17381" 2.66806026255525e-05 0.000217436407223991 0.000130472901359934 "ANXA2/CDK4/CDK6/CD74/AGT/CCNB1/CDC6/BAX/CDKN1A/BTC/AGTR2/BMI1/AQP1/CCNA2" 14 +"GO:0010939" "GO:0010939" "regulation of necrotic cell death" "8/743" "30/17381" 2.71970976769794e-05 0.000220603417677694 0.000132373268680233 "BIRC2/TSPO/BOK/CASP8/CAV1/BIRC3/BNIP3/SLC25A4" 8 +"GO:0032743" "GO:0032743" "positive regulation of interleukin-2 production" "8/743" "30/17381" 2.71970976769794e-05 0.000220603417677694 0.000132373268680233 "ANXA1/CD4/RUNX1/CD80/CD3E/CD28/CD86/ABL1" 8 +"GO:0043114" "GO:0043114" "regulation of vascular permeability" "8/743" "30/17381" 2.71970976769794e-05 0.000220603417677694 0.000132373268680233 "BDKRB2/ADM/AZU1/ABR/BCR/CEACAM1/ADORA2A/ANGPT1" 8 +"GO:0006970" "GO:0006970" "response to osmotic stress" "12/743" "68/17381" 2.74250922515482e-05 0.000222104620347046 0.000133274066620653 "BDKRB2/TSPO/BAD/ANXA7/CAPN3/BAX/AQP9/AQP1/ZFP36L1/APOBEC1/CASP3/AVP" 12 +"GO:0031294" "GO:0031294" "lymphocyte costimulation" "13/743" "79/17381" 2.786849791464e-05 0.000224991383320222 0.000135006271201557 "CD3G/CD4/AKT1/CD80/CD247/CD3E/CD3D/CDC42/CAV1/CD5/CD28/CD40LG/CD86" 13 +"GO:0048259" "GO:0048259" "regulation of receptor-mediated endocytosis" "13/743" "79/17381" 2.786849791464e-05 0.000224991383320222 0.000135006271201557 "APOC2/ANXA2/APOC3/ARRB1/ARF1/ARRB2/BICD1/CD63/ARF6/APOC1/CBL/B2M/ANGPT1" 13 +"GO:0070231" "GO:0070231" "T cell apoptotic process" "10/743" "48/17381" 2.86843079485394e-05 0.000231216968276777 0.000138741938757487 "ARG2/FAS/AKT1/CD27/BAX/ADA/FASLG/ADAM8/BMP4/BAK1" 10 +"GO:0050680" "GO:0050680" "negative regulation of epithelial cell proliferation" "17/743" "127/17381" 2.8925695155119e-05 0.000232800112640343 0.000139691905881315 "CDKN1B/BRCA2/ACVRL1/CDK6/KLF9/APOE/AR/KRIT1/CDKN2B/CAV1/APOH/CEACAM1/CAV2/CDKN1C/RUNX3/ATP5A1/BMP4" 17 +"GO:1902305" "GO:1902305" "regulation of sodium ion transmembrane transport" "11/743" "58/17381" 2.93161667544481e-05 0.000235576339991101 0.000141357783467836 "ATP1B3/ARF1/ATP2B4/ATP1B2/CAMK2D/CAV3/FXYD2/ATP1A2/ANK3/ATP1B1/ACTN4" 11 +"GO:0006188" "GO:0006188" "IMP biosynthetic process" "5/743" "10/17381" 2.96670807402627e-05 0.00023583278468642 0.000141511663325693 "AMPD3/AMPD1/ATIC/AMPD2/ADSL" 5 +"GO:0019755" "GO:0019755" "one-carbon compound transport" "5/743" "10/17381" 2.96670807402627e-05 0.00023583278468642 0.000141511663325693 "AQP3/AQP9/AQP1/CA2/AQP5" 5 +"GO:0035376" "GO:0035376" "sterol import" "5/743" "10/17381" 2.96670807402627e-05 0.00023583278468642 0.000141511663325693 "APOC3/SCARB1/CD36/APOA1/APOA2" 5 +"GO:0060546" "GO:0060546" "negative regulation of necroptotic process" "5/743" "10/17381" 2.96670807402627e-05 0.00023583278468642 0.000141511663325693 "BIRC2/BOK/CAV1/BIRC3/SLC25A4" 5 +"GO:0070508" "GO:0070508" "cholesterol import" "5/743" "10/17381" 2.96670807402627e-05 0.00023583278468642 0.000141511663325693 "APOC3/SCARB1/CD36/APOA1/APOA2" 5 +"GO:1904321" "GO:1904321" "response to forskolin" "5/743" "10/17381" 2.96670807402627e-05 0.00023583278468642 0.000141511663325693 "ADCY1/ADCY6/ADCY5/ADCY3/ADCY2" 5 +"GO:1904322" "GO:1904322" "cellular response to forskolin" "5/743" "10/17381" 2.96670807402627e-05 0.00023583278468642 0.000141511663325693 "ADCY1/ADCY6/ADCY5/ADCY3/ADCY2" 5 +"GO:0010720" "GO:0010720" "positive regulation of cell development" "41/743" "488/17381" 3.02570696855997e-05 0.000237789279124654 0.000142685659479833 "APP/SCARB2/BMP2/ATF1/ABL2/CAMK2B/AGT/BIN1/AGER/ARHGDIA/TSPO/APOE/ARF1/BAD/ADRA2B/ASPA/ADD1/ASCL1/ADRA2C/CDH5/BMPR2/CDC42/BDNF/APOA1/ATP6AP1/BMP7/BCL2/BRAF/BCL6/ATOH1/RHOA/APBB1/CALR/ARSB/BMP6/ADCYAP1/BMP5/BMP4/C1QBP/CDH4/ABL1" 41 +"GO:0006091" "GO:0006091" "generation of precursor metabolites and energy" "39/743" "455/17381" 3.02843866577051e-05 0.000237789279124654 0.000142685659479833 "ALDOC/ALDOA/CALM1/BID/CDK1/AVPR1A/ENTPD5/AQP7/ACOX1/AKT2/CCNB1/ATP5C1/AKT1/ASPH/ARNT/ACO1/ADRB3/ATP7A/ACTN3/CAT/BPGM/ADH5/ATP5D/ACO2/ACADVL/ALDOB/CBFA2T3/AKR1B1/AGL/AOC2/AVP/ALDH2/ATP5B/AOX1/RUNX1T1/ADSL/BNIP3/SLC25A4/ASIP" 39 +"GO:0001523" "GO:0001523" "retinoid metabolic process" "14/743" "91/17381" 3.03118455102937e-05 0.000237789279124654 0.000142685659479833 "APOC2/APOC3/APOE/APOA4/OPN1SW/APOA1/ADH7/ADH5/ADH4/ALDH1A1/ALDH1A3/APOA2/ABCA4/APOB" 14 +"GO:0050818" "GO:0050818" "regulation of coagulation" "14/743" "91/17381" 3.03118455102937e-05 0.000237789279124654 0.000142685659479833 "ANXA2/ASIC2/APOE/CD34/CD9/SERPINC1/CD36/ALOX12/CAV1/ABAT/APOH/CEACAM1/ANXA5/SERPING1" 14 +"GO:0003197" "GO:0003197" "endocardial cushion development" "9/743" "39/17381" 3.03267486419848e-05 0.000237789279124654 0.000142685659479833 "BMP2/ACVRL1/BMPR1A/BMPR2/BMP7/ACVR1/BMP5/JAG1/BMP4" 9 +"GO:0006636" "GO:0006636" "unsaturated fatty acid biosynthetic process" "9/743" "39/17381" 3.03267486419848e-05 0.000237789279124654 0.000142685659479833 "ANXA1/AVPR1A/CD74/ALOX12/ALOX15/CBR1/ALOX12B/AVP/ALOX15B" 9 +"GO:0046461" "GO:0046461" "neutral lipid catabolic process" "9/743" "39/17381" 3.03267486419848e-05 0.000237789279124654 0.000142685659479833 "APOC2/APOC3/APOE/APOA4/AADAC/APOA1/APOA2/DAGLA/APOB" 9 +"GO:0046464" "GO:0046464" "acylglycerol catabolic process" "9/743" "39/17381" 3.03267486419848e-05 0.000237789279124654 0.000142685659479833 "APOC2/APOC3/APOE/APOA4/AADAC/APOA1/APOA2/DAGLA/APOB" 9 +"GO:0071377" "GO:0071377" "cellular response to glucagon stimulus" "9/743" "39/17381" 3.03267486419848e-05 0.000237789279124654 0.000142685659479833 "ADCY1/ADCY6/ADCY5/ADCY9/ADCY7/ADCY8/ADCY3/ARG1/ADCY2" 9 +"GO:1903555" "GO:1903555" "regulation of tumor necrosis factor superfamily cytokine production" "16/743" "115/17381" 3.04561245755371e-05 0.000238442427652655 0.00014307758181039 "AXL/BPI/ARG2/AZU1/ACP5/TSPO/CD34/CD36/TNFRSF8/ARRB2/BCL3/CD2/CD14/ADAM8/CD86/ANGPT1" 16 +"GO:0050848" "GO:0050848" "regulation of calcium-mediated signaling" "13/743" "80/17381" 3.19936462089719e-05 0.000250101388416057 0.000150073551147189 "CALM1/CD4/CALM3/ATP2B4/CD3E/CAMK2D/CALM2/ACTN3/ADA/CD8A/BST1/CASQ2/CDH13" 13 +"GO:1902806" "GO:1902806" "regulation of cell cycle G1/S phase transition" "21/743" "181/17381" 3.20613922429993e-05 0.000250252948503049 0.000150164494906482 "ANXA1/CDKN1B/CDC25C/BID/AIF1/CDK1/CDKN2D/CCNB1/AKT1/CCND2/ATP2B4/CASP2/CDC6/BAX/CDK2/CDKN2B/CDKN1A/BCL2/ATM/APEX1/CCND1" 21 +"GO:0001933" "GO:0001933" "negative regulation of protein phosphorylation" "37/743" "424/17381" 3.28901832741155e-05 0.000255560815651788 0.00015334948511015 "BDKRB2/CDKN1B/CALM1/BDKRB1/CALM3/CDKN2D/CCNB1/AKT1/APOE/ARRB1/APC/CAV3/ADAR/CALM2/CBLB/BGN/BAX/ADARB1/BMP7/CDKN2B/CDKN1A/ARRB2/CAV1/ATF3/CEACAM1/AMBP/ADORA2A/CDKN1C/CASP3/CDKN2A/LDLRAD4/BMP4/CDKN2C/ABL1/CBL/BAK1/ANGPT1" 37 +"GO:0019372" "GO:0019372" "lipoxygenase pathway" "6/743" "16/17381" 3.31364845028695e-05 0.000255560815651788 0.00015334948511015 "ALOX12/ALOX15/ALOX12B/ALOX5/ALOX5AP/ALOX15B" 6 +"GO:0043101" "GO:0043101" "purine-containing compound salvage" "6/743" "16/17381" 3.31364845028695e-05 0.000255560815651788 0.00015334948511015 "ADK/AMPD3/AMPD1/ADA/APRT/AMPD2" 6 +"GO:0045717" "GO:0045717" "negative regulation of fatty acid biosynthetic process" "6/743" "16/17381" 3.31364845028695e-05 0.000255560815651788 0.00015334948511015 "APOC3/ACADVL/ACADL/CEACAM1/BRCA1/APOC1" 6 +"GO:0045723" "GO:0045723" "positive regulation of fatty acid biosynthetic process" "6/743" "16/17381" 3.31364845028695e-05 0.000255560815651788 0.00015334948511015 "ANXA1/APOC2/AVPR1A/APOA4/APOA1/AVP" 6 +"GO:0051883" "GO:0051883" "killing of cells in other organism involved in symbiotic interaction" "6/743" "16/17381" 3.31364845028695e-05 0.000255560815651788 0.00015334948511015 "ALB/AZU1/BAD/CAMP/C9/ARG1" 6 +"GO:0051957" "GO:0051957" "positive regulation of amino acid transport" "6/743" "16/17381" 3.31364845028695e-05 0.000255560815651788 0.00015334948511015 "AVPR1A/AGT/ABAT/CCK/ADORA2A/AVP" 6 +"GO:0055070" "GO:0055070" "copper ion homeostasis" "6/743" "16/17381" 3.31364845028695e-05 0.000255560815651788 0.00015334948511015 "APP/ARF1/ATOX1/ATP7A/XIAP/ATP7B" 6 +"GO:0040017" "GO:0040017" "positive regulation of locomotion" "41/743" "490/17381" 3.32303338958556e-05 0.000255903240939067 0.000153554957695448 "APP/BMP2/AIF1/BDKRB1/SCARB1/AKT2/CD74/AGT/AKT1/ACVR1B/AZU1/AGER/C3AR1/APC/CASR/ATP7A/BMPR2/ALOX12/ADRA2A/BMP7/ANXA3/AAMP/BCL2/CD40/RHOA/ACVR1/CALR/AQP1/RHOB/C5AR1/CAV2/ACTN4/ATP5B/CDH13/ADAM8/ADAM10/ATP5A1/BMP4/C1QBP/ABL1/ANGPT1" 41 +"GO:0034599" "GO:0034599" "cellular response to oxidative stress" "28/743" "283/17381" 3.36398741804602e-05 0.000258672138014683 0.000155216436744127 "ANXA1/AIF1/AXL/CDK1/AKT1/ATP2A2/BTK/ARNT/APOA4/CD36/ATP7A/NUDT2/CAT/CDK2/BMP7/BCL2/ALDH3B1/AKR1B1/AQP1/RHOB/PARP1/ARNTL/ARG1/CCNA2/APEX1/BNIP3/ATF4/ABL1" 28 +"GO:1903034" "GO:1903034" "regulation of response to wounding" "20/743" "168/17381" 3.38861987883174e-05 0.000259794190710434 0.00015588972541994 "ANXA1/ANXA2/ASIC2/AGER/APOE/CD34/CD9/SERPINC1/CD36/ATP7A/CAPN3/ALOX12/ADRA2A/CAV1/ABAT/BRAF/APOH/CEACAM1/APCS/SERPING1" 20 +"GO:1904018" "GO:1904018" "positive regulation of vasculature development" "20/743" "168/17381" 3.38861987883174e-05 0.000259794190710434 0.00015588972541994 "APLNR/ADM/ACVRL1/C6/C3AR1/RUNX1/CD34/C5/BTG1/ALOX12/ANXA3/CD40/C3/CEACAM1/AQP1/RHOB/C5AR1/ANGPT2/BRCA1/ABL1" 20 +"GO:0009081" "GO:0009081" "branched-chain amino acid metabolic process" "7/743" "23/17381" 3.41002987739663e-05 0.000260663288264809 0.000156411228147711 "BCAT1/ACAT1/AUH/ACADSB/BCKDHA/BCAT2/BCKDHB" 7 +"GO:0010226" "GO:0010226" "response to lithium ion" "7/743" "23/17381" 3.41002987739663e-05 0.000260663288264809 0.000156411228147711 "CDKN1B/FAS/ADCY1/ACTA1/ASCL1/CALR/CDH1" 7 +"GO:0045428" "GO:0045428" "regulation of nitric oxide biosynthetic process" "11/743" "59/17381" 3.46599327524637e-05 0.000264264144469541 0.000158571924980452 "AIF1/AGT/AKT1/ACP5/TSPO/CD34/ATP2B4/CD36/CAV1/ASS1/AGTR2" 11 +"GO:0051055" "GO:0051055" "negative regulation of lipid biosynthetic process" "10/743" "49/17381" 3.46734983758103e-05 0.000264264144469541 0.000158571924980452 "BMP2/APOC3/APOE/ATP1A1/ACADVL/ACADL/CEACAM1/BMP5/BRCA1/APOC1" 10 +"GO:0051216" "GO:0051216" "cartilage development" "21/743" "182/17381" 3.48187864991724e-05 0.000264981206078261 0.000159002198409534 "BMP2/BBS2/ACVRL1/AMELX/BMPR1A/SERPINH1/RUNX1/RUNX2/BMP8B/ATP7A/BMPR2/BMP1/BMP7/BMPR1B/BMP6/BMP5/RUNX3/NKX3-2/CD44/BMP4/BMP3" 21 +"GO:0098742" "GO:0098742" "cell-cell adhesion via plasma-membrane adhesion molecules" "25/743" "239/17381" 3.50377819770195e-05 0.000266256272732858 0.000159767303241684 "BMP2/ALCAM/CD6/CDH7/CDH3/CDH2/CDH5/CDH8/CDH16/APOA1/CDH10/CDH11/ARVCF/CDH18/ACVR1/CEACAM1/CDH12/CDH1/CDH9/CDH15/CDH13/CBLN1/CDH17/CDH4/CDH6" 25 +"GO:0045862" "GO:0045862" "positive regulation of proteolysis" "35/743" "393/17381" 3.51713359926921e-05 0.000266776662076887 0.000160079563310819 "APP/CASP1/BID/CDK1/C6/CASP9/FAS/CCNB1/BUB1B/AKT1/ASPH/APOE/ARRB1/BAD/BOK/CASP2/CAV3/CDC20/FOXL2/CAPN3/BAX/ALOX12/ADRA2A/FASLG/CASP8/CAV1/C3/CCK/CBFA2T3/CASP7/CASP3/APAF1/ADAM8/CDC27/BAK1" 35 +"GO:0030509" "GO:0030509" "BMP signaling pathway" "19/743" "155/17381" 3.52093642895679e-05 0.000266776662076887 0.000160079563310819 "BMP2/ACVR2B/ACVRL1/BMPR1A/RUNX2/BMP8B/BMPR2/AMH/AMHR2/BMP7/XIAP/BMPR1B/ACVR1/BMP6/BMP5/ACVR2A/BMP4/ABL1/BMP3" 19 +"GO:1903426" "GO:1903426" "regulation of reactive oxygen species biosynthetic process" "13/743" "81/17381" 3.6641989037532e-05 0.000277225574955012 0.000166349442383379 "AIF1/ARG2/AGT/AKT1/ACP5/TSPO/CD34/ADGRB1/ATP2B4/CD36/CAV1/ASS1/AGTR2" 13 +"GO:0006809" "GO:0006809" "nitric oxide biosynthetic process" "12/743" "70/17381" 3.70531077671901e-05 0.000279926763058699 0.000167970292605779 "AIF1/ARG2/AGT/AKT1/ACP5/TSPO/CD34/ATP2B4/CD36/CAV1/ASS1/AGTR2" 12 +"GO:2001234" "GO:2001234" "negative regulation of apoptotic signaling pathway" "23/743" "211/17381" 3.74038604350386e-05 0.000282164690599599 0.000169313162932889 "BDKRB2/BID/FAS/CD74/CDKN2D/BCL2L2/AKT1/AR/SLC25A5/BOK/BAX/FASLG/ARRB2/CASP8/BCL2/ACVR1/BMP5/BRCA1/AVP/CD44/BCL2L1/BMP4/PTTG1IP" 23 +"GO:0010950" "GO:0010950" "positive regulation of endopeptidase activity" "19/743" "156/17381" 3.85219749044294e-05 0.000289754680422125 0.0001738675427908 "CASP1/BID/CASP9/FAS/ASPH/ARRB1/BAD/BOK/CASP2/FOXL2/BAX/ALOX12/FASLG/CASP8/CCK/CASP7/CASP3/APAF1/BAK1" 19 +"GO:0015718" "GO:0015718" "monocarboxylic acid transport" "19/743" "156/17381" 3.85219749044294e-05 0.000289754680422125 0.0001738675427908 "ANXA1/BDKRB2/AKT2/AKT1/ALB/APOE/APBA1/ACACA/ABCD2/BSG/CD36/ABAT/AQP9/ACACB/AGTR2/CEACAM1/PLIN2/ABCD1/SLC25A20" 19 +"GO:0034766" "GO:0034766" "negative regulation of ion transmembrane transport" "14/743" "93/17381" 3.88959894256871e-05 0.000292143316803963 0.000175300846086283 "CALM1/CALM3/AKT2/AKT1/ACTN2/CAMK2D/CAV3/CALM2/ATP7A/ADRA2A/ATP1A2/CAV1/ANK3/CASQ2" 14 +"GO:0001655" "GO:0001655" "urogenital system development" "30/743" "316/17381" 3.90145192668144e-05 0.000292185437345534 0.00017532612055313 "ANXA1/BMP2/CDKN1B/AQP2/ACVR2B/ARG2/CALB1/AGT/ACAT1/ACTA2/AR/CD34/AMH/BAX/AGTR1/CAT/BMP7/BCL2/AKR1B1/AGTR2/AQP1/BMP6/CDKN1C/ANGPT2/CA2/JAG1/BMP4/ALOX15B/ANGPT1/ARL3" 30 +"GO:0048511" "GO:0048511" "rhythmic process" "30/743" "316/17381" 3.90145192668144e-05 0.000292185437345534 0.00017532612055313 "ANXA1/AXL/AHCY/CDK4/FAS/KLF9/ADCY1/ZFHX3/ARRB1/CASP2/AGRP/AFP/AMH/FOXL2/ANG/BAX/ADA/ARRB2/BCL2/BMPR1B/ATM/ARNTL/ADCYAP1/ADORA2A/AHR/CDK5/AANAT/BCL2L1/ATF4/ADORA1" 30 +"GO:0007173" "GO:0007173" "epidermal growth factor receptor signaling pathway" "17/743" "130/17381" 3.92248009398109e-05 0.000293335758473297 0.00017601637172565 "APP/AGT/AKT1/CAMLG/ADRA2B/ADRA2C/AREG/CBLB/CDC42/ADRA2A/FASLG/BTC/CEACAM1/CDH13/ABL1/CBL/ADORA1" 17 +"GO:0061041" "GO:0061041" "regulation of wound healing" "18/743" "143/17381" 3.93749025191269e-05 0.000294033362967506 0.000176434969896597 "ANXA1/ANXA2/ASIC2/AGER/APOE/CD34/CD9/SERPINC1/CD36/CAPN3/ALOX12/ADRA2A/CAV1/ABAT/APOH/CEACAM1/APCS/SERPING1" 18 +"GO:0021700" "GO:0021700" "developmental maturation" "26/743" "256/17381" 4.08487360421783e-05 0.000304599724810191 0.000182775324320379 "APP/BMP2/BRCA2/AXL/ACVRL1/BFSP1/CAMK2B/CCNB1/ADGRB3/CDH3/ARCN1/RUNX2/BTK/RERE/AP1G1/ASCL1/CDH5/CDC20/ANG/CDKN1A/CDC25B/BCL2/RHOA/CBFB/CD63/CDKN1C" 26 +"GO:0006275" "GO:0006275" "regulation of DNA replication" "16/743" "118/17381" 4.20310729559003e-05 0.000312965183520553 0.000187795024944954 "ATF1/ATR/BRCA2/ATRX/ACVRL1/CDK1/AREG/CDC6/CDC42/CDK2/BCL6/BLM/CALR/BMP6/BMP5/BMP4" 16 +"GO:0050679" "GO:0050679" "positive regulation of epithelial cell proliferation" "20/743" "171/17381" 4.37471603054474e-05 0.000325101855270642 0.000195077645166213 "BMP2/ACVRL1/AKT1/BMPR1A/CDH3/ARNT/BAD/AR/ATP7A/BMPR2/ANG/CDC42/C5AR1/BMP6/CAV2/BMP5/CDH13/ARG1/BMP4/CCND1" 20 +"GO:0042698" "GO:0042698" "ovulation cycle" "15/743" "106/17381" 4.3786665337901e-05 0.000325101855270642 0.000195077645166213 "ANXA1/AXL/ARRB1/CASP2/AFP/AMH/FOXL2/ANG/BAX/ARRB2/BCL2/BMPR1B/ATM/ADCYAP1/BCL2L1" 15 +"GO:0045923" "GO:0045923" "positive regulation of fatty acid metabolic process" "8/743" "32/17381" 4.530660347632e-05 0.000335424424878335 0.000201271711851734 "ANXA1/APOC2/AVPR1A/AKT2/APOA4/ABCD2/APOA1/AVP" 8 +"GO:1901021" "GO:1901021" "positive regulation of calcium ion transmembrane transporter activity" "8/743" "32/17381" 4.530660347632e-05 0.000335424424878335 0.000201271711851734 "CASQ1/CALM1/CALM3/CALM2/CACNA2D1/ATP1B1/ANK2/CACNB2" 8 +"GO:0007202" "GO:0007202" "activation of phospholipase C activity" "7/743" "24/17381" 4.63740548518128e-05 0.000341855715754636 0.000205130813420021 "AVPR1A/AGT/AVPR1B/ADRA1A/ANG/ADCYAP1R1/C5AR1" 7 +"GO:0035588" "GO:0035588" "G-protein coupled purinergic receptor signaling pathway" "7/743" "24/17381" 4.63740548518128e-05 0.000341855715754636 0.000205130813420021 "ADCY5/ADORA3/ADA/ACPP/ADORA2B/ADORA2A/ADORA1" 7 +"GO:0030890" "GO:0030890" "positive regulation of B cell proliferation" "9/743" "41/17381" 4.6439530082224e-05 0.000341855715754636 0.000205130813420021 "CD74/CD81/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/BST1" 9 +"GO:0090382" "GO:0090382" "phagosome maturation" "9/743" "41/17381" 4.6439530082224e-05 0.000341855715754636 0.000205130813420021 "ATP6V1C1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1" 9 +"GO:0001776" "GO:0001776" "leukocyte homeostasis" "13/743" "83/17381" 4.77325864620867e-05 0.000350875191677981 0.000210542957630317 "ANXA1/AXL/FAS/CD74/AKT1/CACNA1F/BAX/ADA/BCL2/CASP3/ABL1/TNFRSF17/BAK1" 13 +"GO:1903706" "GO:1903706" "regulation of hemopoiesis" "38/743" "448/17381" 4.7886269422896e-05 0.000351505594699981 0.000210921231500624 "ANXA1/AXL/CD4/CDK6/FAS/CD74/ACVR1B/AGER/RUNX1/CD80/BTK/ARNT/BAD/BGLAP/CD27/PRDM1/ADA/ATP6AP1/ZFP36L2/CASP8/BRAF/BCL6/CBFB/CD2/CEACAM1/ZFP36L1/CAMK4/ACVR2A/C1QC/CA2/CD28/ADAM8/JAG1/APCS/BMP4/CD86/ABL1/B2M" 38 +"GO:0014061" "GO:0014061" "regulation of norepinephrine secretion" "6/743" "17/17381" 4.93632071266471e-05 0.000361321919208485 0.000216811525383174 "AGT/ADRA2B/ADRA2C/ADRA2A/AGTR2/ADORA2A" 6 +"GO:0055119" "GO:0055119" "relaxation of cardiac muscle" "6/743" "17/17381" 4.93632071266471e-05 0.000361321919208485 0.000216811525383174 "ATP2A2/ATP1A1/CAMK2D/ATP1A2/CAMK2G/ATP1B1" 6 +"GO:0071383" "GO:0071383" "cellular response to steroid hormone stimulus" "26/743" "259/17381" 4.9779079673495e-05 0.000363851323884656 0.000218329296813575 "ANXA1/CASP9/KLF9/ATP2B1/RUNX1/CDK7/AR/ATP1A3/NR0B1/ATP1A1/ATP1A2/BMP7/CCNE1/ZFP36L2/ARRB2/CBFB/AGTR2/CALR/AQP1/PARP1/ARNTL/ZFP36L1/ADCYAP1/BRCA1/ARG1/BMP4" 26 +"GO:0031668" "GO:0031668" "cellular response to extracellular stimulus" "23/743" "215/17381" 5.02472753022903e-05 0.00036675550026707 0.000220071950325524 "AIF1/AQP2/AXL/AES/AVPR1A/FAS/ALB/ATP2B1/BGLAP/AOC1/CASR/BMPR2/CBS/CDKN2B/CDKN1A/ADORA2B/BCL2/AQP3/ATF3/ASNS/ATF4/CBL/ASGR1" 23 +"GO:0035264" "GO:0035264" "multicellular organism growth" "18/743" "146/17381" 5.19969827104934e-05 0.000378992092291272 0.000227414527792373 "APP/BBS2/ATRX/ADRB2/APBA2/CDK4/APBA1/AR/ADD1/ADRB3/BBS4/CDC42/ADARB1/ADRB1/BCL2/ATM/ZFP36L1/CDKN1C" 18 +"GO:0015791" "GO:0015791" "polyol transport" "5/743" "11/17381" 5.24743720732091e-05 0.000380328957253301 0.000228216714751536 "AQP2/AQP7/AQP3/AQP9/AQP1" 5 +"GO:0034379" "GO:0034379" "very-low-density lipoprotein particle assembly" "5/743" "11/17381" 5.24743720732091e-05 0.000380328957253301 0.000228216714751536 "APOC3/APOC4/ARF1/APOC1/APOB" 5 +"GO:0046689" "GO:0046689" "response to mercury ion" "5/743" "11/17381" 5.24743720732091e-05 0.000380328957253301 0.000228216714751536 "AQP2/BSG/ALAD/AQP9/AQP1" 5 +"GO:2000425" "GO:2000425" "regulation of apoptotic cell clearance" "5/743" "11/17381" 5.24743720732091e-05 0.000380328957253301 0.000228216714751536 "C2/ALOX15/C3/C4B/C4A" 5 +"GO:0002262" "GO:0002262" "myeloid cell homeostasis" "17/743" "133/17381" 5.26471676656223e-05 0.000381047682055378 0.000228647986181208 "ANXA1/ALAS2/AXL/CDK6/ACVR1B/ARNT/AMPD3/ADD1/ADAR/BAX/BCL6/ZFP36L1/ACVR2A/CASP3/BMP4/B2M/BAK1" 17 +"GO:0090092" "GO:0090092" "regulation of transmembrane receptor protein serine/threonine kinase signaling pathway" "23/743" "216/17381" 5.4020370259196e-05 0.000390440525267233 0.000234284169750997 "BMP2/ACVR2B/ACVRL1/BMPR1A/ACVR1B/BMP8B/CAV3/BMPR2/BMP7/CDKN2B/XIAP/CAV1/ACVR1/PARP1/BMP6/CAV2/CDKN1C/BMP5/ACVR2A/LDLRAD4/BMP4/ABL1/BMP3" 23 +"GO:0000041" "GO:0000041" "transition metal ion transport" "15/743" "108/17381" 5.46419958739391e-05 0.000393285575309645 0.000235991344452266 "ATP6V1C1/ATP6V1B2/ATP6V0A1/ATOX1/ATP7A/ATP6V1B1/ATP6V1A/ATP6AP1/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1/ATP7B/ARHGAP1/B2M" 15 +"GO:0006721" "GO:0006721" "terpenoid metabolic process" "15/743" "108/17381" 5.46419958739391e-05 0.000393285575309645 0.000235991344452266 "APOC2/APOC3/APOE/APOA4/ALDH3A2/OPN1SW/APOA1/ADH7/ADH5/ADH4/ALDH1A1/ALDH1A3/APOA2/ABCA4/APOB" 15 +"GO:0044070" "GO:0044070" "regulation of anion transport" "15/743" "108/17381" 5.46419958739391e-05 0.000393285575309645 0.000235991344452266 "AVPR1A/AKT2/AGT/AKT1/APOE/ATP1A2/ABAT/CCK/AGTR2/ADORA2A/CA2/CA7/AVP/ARG1/ADORA1" 15 +"GO:0031348" "GO:0031348" "negative regulation of defense response" "20/743" "174/17381" 5.60901215709581e-05 0.000403147748791261 0.000241909150050185 "ARG2/AGER/ACP5/APOE/ABR/BCR/ADAR/A2M/APOA1/ADA/ARRB2/CEACAM1/ADCYAP1/ADORA2A/APOD/ARG1/APCS/C1QBP/SERPING1/ADORA1" 20 +"GO:0032970" "GO:0032970" "regulation of actin filament-based process" "31/743" "338/17381" 5.62247835503369e-05 0.000403555138520102 0.000242153604603977 "CACNA1C/ABL2/ARHGDIA/ATP2A2/ARF1/ACTN2/ATP1A1/ADD1/CAMK2D/CAV3/BBS4/ADD2/CAPZB/CDC42/APOA1/CAPG/ATP1A2/ALOX15/CAV1/BRAF/CAPZA2/CAPZA1/RHOA/ARHGAP6/ARF6/BST1/BST2/ANK2/CDK5/ARHGDIB/ABL1" 31 +"GO:0010634" "GO:0010634" "positive regulation of epithelial cell migration" "16/743" "121/17381" 5.7324886227029e-05 0.000410881282859938 0.000246549663755264 "SCARB1/AGT/AKT1/BMPR2/ALOX12/ANXA3/AAMP/CD40/CALR/AQP1/RHOB/ATP5B/ATP5A1/BMP4/ABL1/ANGPT1" 16 +"GO:0010574" "GO:0010574" "regulation of vascular endothelial growth factor production" "8/743" "33/17381" 5.75813300326417e-05 0.000411579258175305 0.000246968484437762 "C3AR1/ARNT/C5/ADORA2B/C3/C5AR1/BRCA1/ATF4" 8 +"GO:0010863" "GO:0010863" "positive regulation of phospholipase C activity" "8/743" "33/17381" 5.75813300326417e-05 0.000411579258175305 0.000246968484437762 "ABL2/AVPR1A/AGT/AVPR1B/ADRA1A/ANG/ADCYAP1R1/C5AR1" 8 +"GO:0033135" "GO:0033135" "regulation of peptidyl-serine phosphorylation" "17/743" "134/17381" 5.79462784216595e-05 0.000413046819327945 0.000247849095757424 "APP/BDKRB2/AKT1/ARRB1/ATP2B4/CALCR/CDC42/BAX/ARAF/ARRB2/CAV1/BCL2/BRAF/AVP/CD44/BAK1/ANGPT1" 17 +"GO:0042542" "GO:0042542" "response to hydrogen peroxide" "17/743" "134/17381" 5.79462784216595e-05 0.000413046819327945 0.000247849095757424 "ANXA1/AXL/CDK1/BAD/AREG/CAT/ADA/BCL2/AKR1B1/AQP1/RHOB/CASP3/ARG1/APEX1/BNIP3/ABL1/BAK1" 17 +"GO:0071453" "GO:0071453" "cellular response to oxygen levels" "23/743" "217/17381" 5.80451287609192e-05 0.000413182312706681 0.000247930398674744 "BNIP3L/FAS/CCNB1/AKT1/BACH1/CA9/ARNT/BAD/CD34/CASR/ATP7A/ATP6V1A/ATP6AP1/BMP7/CAV1/BCL2/AQP3/AQP1/ZFP36L1/CCNA2/ADAM8/BNIP3/CBL" 23 +"GO:0030073" "GO:0030073" "insulin secretion" "22/743" "203/17381" 5.9838491369788e-05 0.000425362902250897 0.000255239371805776 "ANXA1/SLC25A6/ACVR2B/CACNA1C/ARRB1/ADCY5/BAD/SLC25A5/BLK/ADRA2C/CASR/ARL2/ADRA2A/CAMK2G/ABAT/CD38/CACNA1D/ARNTL/ADCYAP1/CACNA1E/CACNA1A/SLC25A4" 22 +"GO:0050804" "GO:0050804" "modulation of chemical synaptic transmission" "29/743" "308/17381" 6.06297925065675e-05 0.000430396675200942 0.000258259891552053 "APP/ADRB2/CAMK2B/CALB1/AGT/BCHE/AGER/ATP2A2/APOE/ADRA1A/ARF1/ADGRB1/CDC20/ACHE/ATP1A2/ARRB2/ABAT/BRAF/CD38/ASIC1/ADCYAP1/ADORA2A/CDK5/CA2/CA7/CBLN1/CAMK2A/ABL1/ADORA1" 29 +"GO:0022602" "GO:0022602" "ovulation cycle process" "13/743" "85/17381" 6.16354531084926e-05 0.000435742445131761 0.000261467625352392 "ARRB1/CASP2/AFP/AMH/FOXL2/ANG/BAX/ARRB2/BCL2/BMPR1B/ATM/ADCYAP1/BCL2L1" 13 +"GO:0030193" "GO:0030193" "regulation of blood coagulation" "13/743" "85/17381" 6.16354531084926e-05 0.000435742445131761 0.000261467625352392 "ANXA2/ASIC2/APOE/CD34/CD9/SERPINC1/CD36/ALOX12/CAV1/ABAT/APOH/CEACAM1/SERPING1" 13 +"GO:1900046" "GO:1900046" "regulation of hemostasis" "13/743" "85/17381" 6.16354531084926e-05 0.000435742445131761 0.000261467625352392 "ANXA2/ASIC2/APOE/CD34/CD9/SERPINC1/CD36/ALOX12/CAV1/ABAT/APOH/CEACAM1/SERPING1" 13 +"GO:0045932" "GO:0045932" "negative regulation of muscle contraction" "7/743" "25/17381" 6.20451270240306e-05 0.00043684834333246 0.000262131220509689 "ADRB2/CALCA/ADRA2C/ATP1A2/ADORA2B/GRK2/ADORA1" 7 +"GO:0072012" "GO:0072012" "glomerulus vasculature development" "7/743" "25/17381" 6.20451270240306e-05 0.00043684834333246 0.000262131220509689 "ACTA2/CD34/BMP7/AQP1/ANGPT2/BMP4/ANGPT1" 7 +"GO:1902751" "GO:1902751" "positive regulation of cell cycle G2/M phase transition" "7/743" "25/17381" 6.20451270240306e-05 0.00043684834333246 0.000262131220509689 "APP/CDC25C/CDK1/CDK4/CDC25B/CDC25A/CCND1" 7 +"GO:0002819" "GO:0002819" "regulation of adaptive immune response" "17/743" "135/17381" 6.37106047055064e-05 0.000447357366826317 0.000268437169008418 "ANXA1/C4BPA/CD4/AGER/CD80/BTK/ADA/ALOX15/CD40/BCL6/C4BPB/C3/CEACAM1/CD48/ARG1/CD28/B2M" 17 +"GO:0008203" "GO:0008203" "cholesterol metabolic process" "17/743" "135/17381" 6.37106047055064e-05 0.000447357366826317 0.000268437169008418 "APP/SCARB1/ACAT2/APOE/APOA4/ACACA/ACLY/ABCA1/APOA1/CAT/ACADVL/ACADL/ACACB/APOA2/APOC1/APOB/APOF" 17 +"GO:2000045" "GO:2000045" "regulation of G1/S transition of mitotic cell cycle" "19/743" "162/17381" 6.48908987206141e-05 0.000455027643467721 0.000273039725040382 "ANXA1/CDKN1B/CDC25C/BID/AIF1/CDK1/CCNB1/AKT1/CCND2/CASP2/CDC6/BAX/CDK2/CDKN2B/CDKN1A/BCL2/ATM/APEX1/CCND1" 19 +"GO:0002260" "GO:0002260" "lymphocyte homeostasis" "11/743" "63/17381" 6.52822838442059e-05 0.000455904614169491 0.000273565952056954 "FAS/CD74/AKT1/CACNA1F/BAX/ADA/BCL2/CASP3/ABL1/TNFRSF17/BAK1" 11 +"GO:0019915" "GO:0019915" "lipid storage" "11/743" "63/17381" 6.52822838442059e-05 0.000455904614169491 0.000273565952056954 "APOC4/SCARB1/APOE/ABCA1/CD36/APOA1/CAV1/C3/ACACB/PLIN2/APOB" 11 +"GO:0010657" "GO:0010657" "muscle cell apoptotic process" "12/743" "74/17381" 6.53683524084565e-05 0.000455904614169491 0.000273565952056954 "AGT/ARRB1/CAMK2D/ALOX12/BMP7/ARRB2/APOH/ADCYAP1/CDKN2A/APAF1/BNIP3/CAMK2A" 12 +"GO:0046209" "GO:0046209" "nitric oxide metabolic process" "12/743" "74/17381" 6.53683524084565e-05 0.000455904614169491 0.000273565952056954 "AIF1/ARG2/AGT/AKT1/ACP5/TSPO/CD34/ATP2B4/CD36/CAV1/ASS1/AGTR2" 12 +"GO:0042058" "GO:0042058" "regulation of epidermal growth factor receptor signaling pathway" "13/743" "86/17381" 6.98179049013282e-05 0.000486282177475603 0.000291794034793395 "APP/AGT/AKT1/ADRA2B/ADRA2C/CBLB/CDC42/ADRA2A/FASLG/CEACAM1/CDH13/CBL/ADORA1" 13 +"GO:1901606" "GO:1901606" "alpha-amino acid catabolic process" "14/743" "98/17381" 7.02593304983434e-05 0.0004886989722163 0.000293244234536097 "CDO1/KYAT1/ALDH7A1/AHCY/ACAT1/ATP2B4/AMT/AUH/ASPA/BLMH/CBS/BCAT2/ARG1/AGXT" 14 +"GO:0048243" "GO:0048243" "norepinephrine secretion" "6/743" "18/17381" 7.13753644162232e-05 0.000494254565608492 0.000296577873083153 "AGT/ADRA2B/ADRA2C/ADRA2A/AGTR2/ADORA2A" 6 +"GO:0051016" "GO:0051016" "barbed-end actin filament capping" "6/743" "18/17381" 7.13753644162232e-05 0.000494254565608492 0.000296577873083153 "ADD1/ADD2/CAPZB/CAPG/CAPZA2/CAPZA1" 6 +"GO:0051818" "GO:0051818" "disruption of cells of other organism involved in symbiotic interaction" "6/743" "18/17381" 7.13753644162232e-05 0.000494254565608492 0.000296577873083153 "ALB/AZU1/BAD/CAMP/C9/ARG1" 6 +"GO:2001235" "GO:2001235" "positive regulation of apoptotic signaling pathway" "20/743" "177/17381" 7.14400802077588e-05 0.000494254565608492 0.000296577873083153 "BID/FAS/AGT/BAD/BOK/CASP2/BAX/FASLG/CASP8/CAV1/BCL2/ATF3/BMPR1B/BIK/AGTR2/ADORA2A/APAF1/BCL2L1/BNIP3/BAK1" 20 +"GO:0034383" "GO:0034383" "low-density lipoprotein particle clearance" "8/743" "34/17381" 7.25007201313576e-05 0.000500922866061116 0.000300579192449589 "ANXA2/AP2B1/APOC3/SCARB1/CD36/AP2A1/AP2A2/APOB" 8 +"GO:0007193" "GO:0007193" "adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway" "12/743" "75/17381" 7.48395266631783e-05 0.000515019349045143 0.000309037799071075 "ADCY1/ADCY6/ADCY5/ADCY9/ADCY7/CASR/APLP1/ADRA2A/ADCY8/ADCY3/ADCY2/ADORA1" 12 +"GO:0042632" "GO:0042632" "cholesterol homeostasis" "12/743" "75/17381" 7.48395266631783e-05 0.000515019349045143 0.000309037799071075 "APOC2/APOC3/SCARB1/ABCA2/APOE/APOA4/CAV3/ABCA1/APOA1/CAV1/APOA2/APOB" 12 +"GO:0055092" "GO:0055092" "sterol homeostasis" "12/743" "75/17381" 7.48395266631783e-05 0.000515019349045143 0.000309037799071075 "APOC2/APOC3/SCARB1/ABCA2/APOE/APOA4/CAV3/ABCA1/APOA1/CAV1/APOA2/APOB" 12 +"GO:0007626" "GO:0007626" "locomotory behavior" "21/743" "192/17381" 7.65213506236358e-05 0.000525893744325784 0.000315562989221675 "APP/ASTN1/ASL/APBA2/CALB1/ZFHX3/ALK/CCND2/ARCN1/APOE/APBA1/ADCY5/ATP1A3/ATP7A/ATP1A2/ARRB2/ABAT/CACNA1B/ALDH1A3/ADORA2A/AVP" 21 +"GO:0010948" "GO:0010948" "negative regulation of cell cycle process" "30/743" "328/17381" 7.75238225738789e-05 0.000532076633713294 0.000319273037265033 "CDKN1B/CDC25C/ATRX/CDK1/CDK4/CDKN2D/CCNB1/BUB1B/BUB1/APC/CASP2/CDK9/BAX/CDK2/BMP7/CDKN2B/CDKN1A/ZFP36L2/BCL2/BCL6/BLM/BMI1/ATM/CALR/CCNF/ZFP36L1/BRCA1/APAF1/BMP4/CCND1" 30 +"GO:0034763" "GO:0034763" "negative regulation of transmembrane transport" "14/743" "99/17381" 7.86713961872246e-05 0.000537813045269336 0.000322715175905322 "CALM1/CALM3/AKT2/AKT1/ACTN2/CAMK2D/CAV3/CALM2/ATP7A/ADRA2A/ATP1A2/CAV1/ANK3/CASQ2" 14 +"GO:0043266" "GO:0043266" "regulation of potassium ion transport" "14/743" "99/17381" 7.86713961872246e-05 0.000537813045269336 0.000322715175905322 "ATP1B3/ACTN2/ATP1B2/CAV3/ADRA2A/CAV1/ANK3/CACNA1D/ATP1B1/CASQ2/ADCYAP1/ANK2/ATF4/ADORA1" 14 +"GO:1901184" "GO:1901184" "regulation of ERBB signaling pathway" "14/743" "99/17381" 7.86713961872246e-05 0.000537813045269336 0.000322715175905322 "APP/AGT/AKT1/ADRA2B/ADRA2C/CBLB/CDC42/ADRA2A/FASLG/BTC/CEACAM1/CDH13/CBL/ADORA1" 14 +"GO:0030335" "GO:0030335" "positive regulation of cell migration" "37/743" "442/17381" 7.89822861955085e-05 0.000539226030424481 0.000323563038851201 "APP/BMP2/AIF1/BDKRB1/SCARB1/AKT2/CD74/AGT/AKT1/ACVR1B/C3AR1/APC/ATP7A/BMPR2/ALOX12/ADRA2A/BMP7/ANXA3/AAMP/BCL2/CD40/RHOA/ACVR1/CALR/AQP1/RHOB/C5AR1/ACTN4/ATP5B/CDH13/ADAM8/ADAM10/ATP5A1/BMP4/C1QBP/ABL1/ANGPT1" 37 +"GO:0051962" "GO:0051962" "positive regulation of nervous system development" "39/743" "476/17381" 8.09748882079438e-05 0.000552101510508708 0.000331288981642652 "APP/SCARB2/BMP2/ATF1/ABL2/CAMK2B/AGT/BIN1/ASIC2/AGER/ARHGDIA/ADGRB3/TSPO/APOE/ARF1/ADGRB1/ADRA2B/ASPA/ASCL1/ADGRB2/ADRA2C/BMPR2/CDC20/BDNF/BMP7/MYRF/BCL2/BRAF/BCL6/ATOH1/RHOA/APBB1/ARSB/BMP6/ADCYAP1/BMP5/CBLN1/BMP4/CDH4" 39 +"GO:0009636" "GO:0009636" "response to toxic substance" "23/743" "222/17381" 8.24773917602013e-05 0.000561605924156634 0.000336992113147637 "CDK1/CDK4/FAS/CCNB1/ALB/APOE/APOA4/CD36/ATP7A/ALAD/BLMH/BAX/CAT/ADH5/BMP7/CDKN1A/BCL2/AHR/CDH1/ASNS/ARG1/BPHL/BAK1" 23 +"GO:0002066" "GO:0002066" "columnar/cuboidal epithelial cell development" "10/743" "54/17381" 8.32531536597976e-05 0.000563454951733765 0.000338101623720235 "KLF5/CDK6/BAD/PRDM1/CDKN1A/ARNTL/BMP6/BMP5/NKX3-2/BMP4" 10 +"GO:0050819" "GO:0050819" "negative regulation of coagulation" "10/743" "54/17381" 8.32531536597976e-05 0.000563454951733765 0.000338101623720235 "ANXA2/APOE/CD34/CD9/ALOX12/ABAT/APOH/CEACAM1/ANXA5/SERPING1" 10 +"GO:0097345" "GO:0097345" "mitochondrial outer membrane permeabilization" "10/743" "54/17381" 8.32531536597976e-05 0.000563454951733765 0.000338101623720235 "BNIP3L/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BNIP3/BAK1" 10 +"GO:0098900" "GO:0098900" "regulation of action potential" "10/743" "54/17381" 8.32531536597976e-05 0.000563454951733765 0.000338101623720235 "CACNA1C/ATP2A2/ADRA1A/CAMK2D/CAV3/CACNA2D1/CAV1/ANK3/ANK2/CACNB3" 10 +"GO:0071222" "GO:0071222" "cellular response to lipopolysaccharide" "19/743" "165/17381" 8.32933406910782e-05 0.000563454951733765 0.000338101623720235 "CASP1/CD6/AXL/CDK4/SCARB1/AKT1/TSPO/CD80/BCR/ABCA1/CD36/PRDM1/CD40/RHOA/CD14/BMP6/ARG1/CD86/ABL1" 19 +"GO:0033574" "GO:0033574" "response to testosterone" "9/743" "44/17381" 8.37814044249982e-05 0.000565278706518078 0.000339195969331976 "CDK4/CA9/TSPO/BAD/AR/BGLAP/CALR/AVP/CBL" 9 +"GO:0050999" "GO:0050999" "regulation of nitric-oxide synthase activity" "9/743" "44/17381" 8.37814044249982e-05 0.000565278706518078 0.000339195969331976 "CALM1/SCARB1/AKT1/APOE/ATP2B4/CAV3/CAV1/AGTR2/ACVR2A" 9 +"GO:0000050" "GO:0000050" "urea cycle" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "ASL/CAD/ARG2/ASS1/ARG1" 5 +"GO:0002921" "GO:0002921" "negative regulation of humoral immune response" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "C4BPA/A2M/C4BPB/CD59/SERPING1" 5 +"GO:0006068" "GO:0006068" "ethanol catabolic process" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "ALDH1B1/ADH7/ALDH3B1/ALDH3B2/ALDH2" 5 +"GO:0010896" "GO:0010896" "regulation of triglyceride catabolic process" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "APOC2/APOC3/APOA4/AADAC/APOA1" 5 +"GO:0033197" "GO:0033197" "response to vitamin E" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "ALAD/CAT/ADA/ARG1/CCND1" 5 +"GO:0045060" "GO:0045060" "negative thymic T cell selection" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "FAS/CD74/CD3E/AIRE/CD28" 5 +"GO:0045086" "GO:0045086" "positive regulation of interleukin-2 biosynthetic process" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "CD4/CD80/CD3E/CD28/CD86" 5 +"GO:1904181" "GO:1904181" "positive regulation of membrane depolarization" "5/743" "12/17381" 8.6791664317187e-05 0.000579544339150248 0.000347756074343907 "TSPO/ALOX12/ANK3/CCK/PARP1" 5 +"GO:1901607" "GO:1901607" "alpha-amino acid biosynthetic process" "11/743" "65/17381" 8.78009935905736e-05 0.000585528533287653 0.000351346895133196 "BCAT1/ASL/CAD/AHCY/ATP2B4/CBS/BCAT2/ASS1/ASNS/BHMT/AGXT" 11 +"GO:0022037" "GO:0022037" "metencephalon development" "14/743" "100/17381" 8.79465711989028e-05 0.00058574453790775 0.000351476508889471 "AARS/ARCN1/RERE/CD3E/ASCL1/ATP7A/ATIC/PHOX2A/BCL2/ABAT/AGTR2/CDK5/CBLN1/ABL1" 14 +"GO:0010165" "GO:0010165" "response to X-ray" "8/743" "35/17381" 9.04920707179155e-05 0.000600380084570786 0.000360258581130703 "ANXA1/BRCA2/CCND2/CDKN1A/BLM/ATM/CASP3/CCND1" 8 +"GO:0010573" "GO:0010573" "vascular endothelial growth factor production" "8/743" "35/17381" 9.04920707179155e-05 0.000600380084570786 0.000360258581130703 "C3AR1/ARNT/C5/ADORA2B/C3/C5AR1/BRCA1/ATF4" 8 +"GO:0098801" "GO:0098801" "regulation of renal system process" "8/743" "35/17381" 9.04920707179155e-05 0.000600380084570786 0.000360258581130703 "AVPR1A/AGT/AGTR1/AGTR2/ADORA2A/AVPR2/AVP/ADORA1" 8 +"GO:0051701" "GO:0051701" "interaction with host" "22/743" "209/17381" 9.24749774567986e-05 0.000612750330779683 0.000367681357904921 "SCARB2/SLC25A6/AXL/CDK1/CD4/SCARB1/CD74/ALB/CD80/CD81/BAD/CASP8/CAV1/ANPEP/C9/CAV2/CDH1/GRK2/BCL2L1/APCS/CD86/CBL" 22 +"GO:0045667" "GO:0045667" "regulation of osteoblast differentiation" "15/743" "113/17381" 9.26883569484488e-05 0.000613378832747088 0.000368058491045799 "BMP2/ACVR2B/CDK6/BMPR1A/RUNX2/AREG/BMPR2/ATP6AP1/BMP7/BMPR1B/ACVR1/BMP6/ACVR2A/JAG1/BMP4" 15 +"GO:0009266" "GO:0009266" "response to temperature stimulus" "23/743" "224/17381" 9.4576617790304e-05 0.000625075347464653 0.00037507699466478 "CASQ1/ATR/ADM/ADRB2/CAMK2B/CALCA/AKT1/ATP2B1/CD34/BAG1/CAMK2D/ADRB3/CDH8/ADRB1/CAMK2G/CDKN1A/ARRB2/CASP8/ACADVL/ATM/CD14/CAMK2A/ADORA1" 23 +"GO:0002793" "GO:0002793" "positive regulation of peptide secretion" "25/743" "254/17381" 9.49769862541047e-05 0.000625973339586029 0.000375615835602092 "CASP1/ARRB1/ARF1/BAD/CASP5/CD34/C5/BLK/CASR/ANG/ACHE/ABAT/CD38/APBB1/CD2/AGTR2/CD14/BMP6/ADCYAP1/ADORA2A/CD58/ADAM8/ABL1/ALOX15B/ADORA1" 25 +"GO:0042063" "GO:0042063" "gliogenesis" "25/743" "254/17381" 9.49769862541047e-05 0.000625973339586029 0.000375615835602092 "ANXA1/APP/BMP2/CDK1/CDK6/AKT2/AKT1/AZU1/BIN1/AGER/TSPO/CDH2/BOK/CD9/ASPA/ASCL1/AREG/ASCL2/MYRF/ADCYAP1/ADORA2A/CDK5/BNIP3/CDKN2C/ABL1" 25 +"GO:1901987" "GO:1901987" "regulation of cell cycle phase transition" "37/743" "446/17381" 9.5075370997994e-05 0.000625973339586029 0.000375615835602092 "ANXA1/APP/CDKN1B/CDC25C/BID/AIF1/CDK1/CDK4/CDK6/CDKN2D/CCNB1/BUB1B/AKT1/CCND2/BUB1/ATP2B4/APC/CASP2/CDC20/CDK3/CDC6/BAX/CDK2/CDKN2B/CDKN1A/ZFP36L2/CDC25B/BCL2/BLM/ATM/ZFP36L1/CDKN1C/BRCA1/CDC25A/APEX1/CCND1/CDC27" 37 +"GO:0071216" "GO:0071216" "cellular response to biotic stimulus" "21/743" "195/17381" 9.56927957585311e-05 0.000629237888247012 0.00037757473080675 "CASP1/CD6/AXL/CDK4/SCARB1/AKT1/TSPO/CD80/BTK/BCR/ABCA1/CD36/PRDM1/CD40/RHOA/CD14/BMP6/ARG1/APAF1/CD86/ABL1" 21 +"GO:2001057" "GO:2001057" "reactive nitrogen species metabolic process" "12/743" "77/17381" 9.73738764737635e-05 0.000639479455268688 0.000383720191821537 "AIF1/ARG2/AGT/AKT1/ACP5/TSPO/CD34/ATP2B4/CD36/CAV1/ASS1/AGTR2" 12 +"GO:0042098" "GO:0042098" "T cell proliferation" "20/743" "181/17381" 9.76591532473932e-05 0.000639491121446553 0.000383727192121502 "ANXA1/AIF1/CD6/CD4/ARG2/AGER/CD80/CD3E/BAX/CD151/CCND3/CASP3/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86/ABL1" 20 +"GO:0032768" "GO:0032768" "regulation of monooxygenase activity" "10/743" "55/17381" 9.79063860440853e-05 0.000639491121446553 0.000383727192121502 "CALM1/SCARB1/AKT1/CDH3/APOE/ATP2B4/CAV3/CAV1/AGTR2/ACVR2A" 10 +"GO:2001259" "GO:2001259" "positive regulation of cation channel activity" "10/743" "55/17381" 9.79063860440853e-05 0.000639491121446553 0.000383727192121502 "CASQ1/CALM1/ADRB2/CALM3/ACTN2/CALM2/CACNA2D1/ANK3/ANK2/CACNB2" 10 +"GO:0071772" "GO:0071772" "response to BMP" "19/743" "167/17381" 9.79935187066892e-05 0.000639491121446553 0.000383727192121502 "BMP2/ACVR2B/ACVRL1/BMPR1A/RUNX2/BMP8B/BMPR2/AMH/AMHR2/BMP7/XIAP/BMPR1B/ACVR1/BMP6/BMP5/ACVR2A/BMP4/ABL1/BMP3" 19 +"GO:0071773" "GO:0071773" "cellular response to BMP stimulus" "19/743" "167/17381" 9.79935187066892e-05 0.000639491121446553 0.000383727192121502 "BMP2/ACVR2B/ACVRL1/BMPR1A/RUNX2/BMP8B/BMPR2/AMH/AMHR2/BMP7/XIAP/BMPR1B/ACVR1/BMP6/BMP5/ACVR2A/BMP4/ABL1/BMP3" 19 +"GO:0007249" "GO:0007249" "I-kappaB kinase/NF-kappaB signaling" "26/743" "270/17381" 9.95281342772155e-05 0.000647927462176748 0.000388789425562452 "APP/BIRC2/CASP1/CD4/CD74/RHOH/AKT1/AGER/BTK/CD27/CD36/CAPN3/CASP10/FASLG/BMP7/RHOC/CASP8/CD40/RHOA/BCL3/CD14/BST2/BIRC3/AVPR2/ABL1/ANGPT1" 26 +"GO:0009896" "GO:0009896" "positive regulation of catabolic process" "37/743" "447/17381" 9.95366825952685e-05 0.000647927462176748 0.000388789425562452 "BNIP3L/APOC2/CDKN1B/C4BPA/ADRB2/CDK1/ENTPD5/AKT2/CCNB1/BUB1B/AKT1/APOE/CD81/ARNT/BAD/APOA4/APC/ABCD2/CAV3/AADAC/CDC20/BAX/ACTN3/APOA1/ADRA2A/ZFP36L2/CAV1/BARD1/C4BPB/CBFA2T3/APOA2/ATM/ZFP36L1/ADAM8/BNIP3/PTTG1IP/CDC27" 37 +"GO:0002029" "GO:0002029" "desensitization of G-protein coupled receptor protein signaling pathway" "6/743" "19/17381" 0.000100560033352984 0.000648799378788408 0.000389312619867949 "APLNR/ADM/ADRB2/ARRB1/ARRB2/GRK2" 6 +"GO:0003323" "GO:0003323" "type B pancreatic cell development" "6/743" "19/17381" 0.000100560033352984 0.000648799378788408 0.000389312619867949 "CDK6/BAD/ARNTL/BMP6/BMP5/BMP4" 6 +"GO:0022401" "GO:0022401" "negative adaptation of signaling pathway" "6/743" "19/17381" 0.000100560033352984 0.000648799378788408 0.000389312619867949 "APLNR/ADM/ADRB2/ARRB1/ARRB2/GRK2" 6 +"GO:0034104" "GO:0034104" "negative regulation of tissue remodeling" "6/743" "19/17381" 0.000100560033352984 0.000648799378788408 0.000389312619867949 "AGT/CALCA/AGER/ABR/BCR/CD38" 6 +"GO:0055093" "GO:0055093" "response to hyperoxia" "6/743" "19/17381" 0.000100560033352984 0.000648799378788408 0.000389312619867949 "CDK4/FAS/CAT/CDKN1A/CAV1/BNIP3" 6 +"GO:1902307" "GO:1902307" "positive regulation of sodium ion transmembrane transport" "6/743" "19/17381" 0.000100560033352984 0.000648799378788408 0.000389312619867949 "ATP1B3/ARF1/ATP1B2/ANK3/ATP1B1/ACTN4" 6 +"GO:1902652" "GO:1902652" "secondary alcohol metabolic process" "17/743" "140/17381" 0.000100792813828557 0.000648799378788408 0.000389312619867949 "APP/SCARB1/ACAT2/APOE/APOA4/ACACA/ACLY/ABCA1/APOA1/CAT/ACADVL/ACADL/ACACB/APOA2/APOC1/APOB/APOF" 17 +"GO:0031018" "GO:0031018" "endocrine pancreas development" "9/743" "45/17381" 0.000100798975950895 0.000648799378788408 0.000389312619867949 "ANXA1/CDK6/AKT1/BAD/ARNTL/BMP6/BMP5/BMP4/BAK1" 9 +"GO:0060443" "GO:0060443" "mammary gland morphogenesis" "9/743" "45/17381" 0.000100798975950895 0.000648799378788408 0.000389312619867949 "DDR1/AR/CAV3/AREG/BAX/CAPN1/CAV1/ARG1/BMP4" 9 +"GO:1902108" "GO:1902108" "regulation of mitochondrial membrane permeability involved in apoptotic process" "11/743" "66/17381" 0.000101351308898428 0.000651544128632748 0.000390959609349933 "BNIP3L/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BNIP3/CAMK2A/BAK1" 11 +"GO:0032640" "GO:0032640" "tumor necrosis factor production" "15/743" "114/17381" 0.000102598620736527 0.000658744246044082 0.000395280045935427 "APP/AXL/BPI/ARG2/AZU1/ACP5/TSPO/CD34/CD36/TNFRSF8/ARRB2/BCL3/CD2/CD14/ANGPT1" 15 +"GO:2001236" "GO:2001236" "regulation of extrinsic apoptotic signaling pathway" "18/743" "154/17381" 0.000104776751803421 0.000671895527363947 0.000403171483493241 "BID/FAS/AGT/AKT1/AR/BAX/FASLG/CASP8/CAV1/BCL2/ATF3/BMPR1B/AGTR2/ACVR1/BMP5/BRCA1/BCL2L1/BMP4" 18 +"GO:0045822" "GO:0045822" "negative regulation of heart contraction" "7/743" "27/17381" 0.000106371018872047 0.000678754651865403 0.000407287306992715 "ATP2A2/ADRA1A/ATP1A1/ATP1A2/AGTR2/GRK2/ADORA1" 7 +"GO:0061437" "GO:0061437" "renal system vasculature development" "7/743" "27/17381" 0.000106371018872047 0.000678754651865403 0.000407287306992715 "ACTA2/CD34/BMP7/AQP1/ANGPT2/BMP4/ANGPT1" 7 +"GO:0061440" "GO:0061440" "kidney vasculature development" "7/743" "27/17381" 0.000106371018872047 0.000678754651865403 0.000407287306992715 "ACTA2/CD34/BMP7/AQP1/ANGPT2/BMP4/ANGPT1" 7 +"GO:1904030" "GO:1904030" "negative regulation of cyclin-dependent protein kinase activity" "7/743" "27/17381" 0.000106371018872047 0.000678754651865403 0.000407287306992715 "CDKN1B/APC/CDKN1A/CDKN1C/CASP3/CDKN2A/CDKN2C" 7 +"GO:0006814" "GO:0006814" "sodium ion transport" "23/743" "226/17381" 0.000108232126050595 0.000689779867379098 0.000413902996952624 "ATP12A/ADRB2/ATP1B3/AKT1/ASIC2/ARF1/ATP1A3/ATP2B4/ATP1B2/ATP1A1/ATP4B/CAMK2D/CAV3/SHROOM2/FXYD2/ATP1A2/ATP4A/ANK3/ATP1A4/ATP1B1/HCN2/ASIC1/ACTN4" 23 +"GO:0033138" "GO:0033138" "positive regulation of peptidyl-serine phosphorylation" "14/743" "102/17381" 0.000109383399577944 0.000696259646759973 0.000417791194089381 "APP/AKT1/ARRB1/ATP2B4/CALCR/CDC42/ARAF/ARRB2/CAV1/BCL2/BRAF/AVP/CD44/ANGPT1" 14 +"GO:0033280" "GO:0033280" "response to vitamin D" "8/743" "36/17381" 0.000112028327246317 0.000711345513496552 0.00042684348127431 "ALPL/CD4/CDKN2D/ATP2B1/BGLAP/CASR/BMP7/AQP3" 8 +"GO:0043094" "GO:0043094" "cellular metabolic compound salvage" "8/743" "36/17381" 0.000112028327246317 0.000711345513496552 0.00042684348127431 "ADK/AMPD3/AMPD1/CDA/ADA/APRT/AMPD2/BHMT" 8 +"GO:0015748" "GO:0015748" "organophosphate ester transport" "13/743" "90/17381" 0.000112691315940701 0.000714678382344521 0.000428843372065362 "APOC2/SLC25A6/APOC3/SCARB1/APOE/SLC25A5/APOA4/ABCA1/APOA1/APOA2/ABCA4/APOC1/SLC25A4" 13 +"GO:0045740" "GO:0045740" "positive regulation of DNA replication" "10/743" "56/17381" 0.000114685340608958 0.00072643407301268 0.000435897384263901 "ATF1/ATRX/CDK1/AREG/CDC42/CDK2/CALR/BMP6/BMP5/BMP4" 10 +"GO:0042446" "GO:0042446" "hormone biosynthetic process" "11/743" "67/17381" 0.000116646183282229 0.000737951098393077 0.000442808185153232 "BMP2/ADM/SCARB1/TSPO/ARNT/ATP1A1/ASMT/AKR1B1/BMP6/BMP5/AANAT" 11 +"GO:0030902" "GO:0030902" "hindbrain development" "17/743" "142/17381" 0.000120257359069479 0.000759867928186271 0.000455959397538673 "AARS/ARCN1/RERE/CD3E/ASCL1/ATP7A/ATIC/PHOX2A/BMP7/BCL2/ABAT/AGTR2/C5AR1/BMP5/CDK5/CBLN1/ABL1" 17 +"GO:0030278" "GO:0030278" "regulation of ossification" "20/743" "184/17381" 0.000122585815120309 0.000773636089326343 0.000464220994358039 "BMP2/ADRB2/ACVR2B/CDK6/CALCA/BMPR1A/RUNX2/BGLAP/AREG/BMPR2/ATP6AP1/BMP7/BCL2/BMPR1B/ACVR1/BMP6/ACVR2A/AHSG/JAG1/BMP4" 20 +"GO:0051099" "GO:0051099" "positive regulation of binding" "19/743" "170/17381" 0.000124342137731175 0.000783764388256799 0.000470298488758212 "APP/BMP2/ANXA2/CALM3/APOE/ARRB1/AMFR/ADD1/CALM2/ADD2/KRIT1/CDK9/BDNF/CAV1/PARP1/CDK5/BMP4/ABL1/B2M" 19 +"GO:0055088" "GO:0055088" "lipid homeostasis" "15/743" "116/17381" 0.000125221846550666 0.000788349216422987 0.000473049618804539 "APOC2/APOC3/APOC4/SCARB1/ABCA2/APOE/APOA4/ACACA/CAV3/ABCA1/ASGR2/APOA1/CAV1/APOA2/APOB" 15 +"GO:0015908" "GO:0015908" "fatty acid transport" "13/743" "91/17381" 0.000126421227679103 0.000792711045679609 0.000475666938165237 "ANXA1/BDKRB2/AKT2/AKT1/APOE/ACACA/ABCD2/CD36/ACACB/AGTR2/PLIN2/ABCD1/SLC25A20" 13 +"GO:0043154" "GO:0043154" "negative regulation of cysteine-type endopeptidase activity involved in apoptotic process" "13/743" "91/17381" 0.000126421227679103 0.000792711045679609 0.000475666938165237 "BIRC2/CDKN2D/AKT1/ARRB1/CD27/ARRB2/XIAP/AQP1/BIRC3/ADORA2A/BIRC5/AVP/CD44" 13 +"GO:1901570" "GO:1901570" "fatty acid derivative biosynthetic process" "13/743" "91/17381" 0.000126421227679103 0.000792711045679609 0.000475666938165237 "ANXA1/AVPR1A/CD74/ACAT1/ACACA/ACLY/ALOX12/ALOX15/CBR1/BDH1/AVP/ALOX5/ALOX5AP" 13 +"GO:0090068" "GO:0090068" "positive regulation of cell cycle process" "26/743" "274/17381" 0.000126527405551953 0.000792711045679609 0.000475666938165237 "ANXA1/APP/CDKN1B/CDC25C/AIF1/ATRX/CDK1/CDK4/CCNB1/CXCR5/CCND2/CASP2/CDC6/CDC42/BAX/CDK2/CDKN1A/CDC25B/BTC/RHOA/ATM/BRCA1/CDC25A/CD28/APEX1/CCND1" 26 +"GO:0007265" "GO:0007265" "Ras protein signal transduction" "30/743" "338/17381" 0.000132848908537653 0.000831309675553027 0.000498828078897825 "ARHGAP5/AIF1/APOC3/ARHGDIG/ARHGDIA/APOE/ARRB1/ADRA1A/ABR/BCR/ABCA1/CDC42/APOA1/AGTR1/CDK2/RHOG/ADRA2A/CDKN1A/ARHGAP4/BCL6/RHOA/ARHGAP6/ARF6/RHOB/CDKN2A/CDH13/CCNA2/ARHGAP1/ARHGDIB/ABL1" 30 +"GO:0007156" "GO:0007156" "homophilic cell adhesion via plasma membrane adhesion molecules" "18/743" "157/17381" 0.000134323451985394 0.000838508883021004 0.000503147969471032 "CDH7/CDH3/CDH2/CDH5/CDH8/CDH16/CDH10/CDH11/CDH18/CEACAM1/CDH12/CDH1/CDH9/CDH15/CDH13/CDH17/CDH4/CDH6" 18 +"GO:0034614" "GO:0034614" "cellular response to reactive oxygen species" "18/743" "157/17381" 0.000134323451985394 0.000838508883021004 0.000503147969471032 "ANXA1/AXL/CDK1/AKT1/BTK/APOA4/CD36/ATP7A/CDK2/BMP7/AKR1B1/AQP1/RHOB/ARG1/CCNA2/APEX1/BNIP3/ABL1" 18 +"GO:0005513" "GO:0005513" "detection of calcium ion" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "CALM1/CALM3/CALM2/CASR/CASQ2" 5 +"GO:0006878" "GO:0006878" "cellular copper ion homeostasis" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "APP/ARF1/ATOX1/ATP7A/ATP7B" 5 +"GO:0010623" "GO:0010623" "programmed cell death involved in cell development" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "CASP5/CASP2/BAX/FASLG/BCL2" 5 +"GO:0032802" "GO:0032802" "low-density lipoprotein particle receptor catabolic process" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "ANXA2/AP2B1/APOE/AP2A1/AP2A2" 5 +"GO:0033604" "GO:0033604" "negative regulation of catecholamine secretion" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "ADRA2B/ADRA2C/ADRA2A/ABAT/AGTR2" 5 +"GO:0034374" "GO:0034374" "low-density lipoprotein particle remodeling" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "AGT/APOE/AGTR1/APOA2/APOB" 5 +"GO:0043383" "GO:0043383" "negative T cell selection" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "FAS/CD74/CD3E/AIRE/CD28" 5 +"GO:0045838" "GO:0045838" "positive regulation of membrane potential" "5/743" "13/17381" 0.000136080416171893 0.000841357411815468 0.000504857231600433 "BID/AKT2/AKT1/BAD/ANK3" 5 +"GO:0001782" "GO:0001782" "B cell homeostasis" "7/743" "28/17381" 0.000136634142327556 0.000842767206847559 0.000505703180310257 "CD74/BAX/ADA/BCL2/CASP3/ABL1/BAK1" 7 +"GO:0055094" "GO:0055094" "response to lipoprotein particle" "7/743" "28/17381" 0.000136634142327556 0.000842767206847559 0.000505703180310257 "APOE/CD81/CD9/ABCA1/CASR/CD36/CDH13" 7 +"GO:0045742" "GO:0045742" "positive regulation of epidermal growth factor receptor signaling pathway" "8/743" "37/17381" 0.000137630100496528 0.000847899726273252 0.000508782952963355 "AGT/AKT1/ADRA2B/ADRA2C/ADRA2A/FASLG/CBL/ADORA1" 8 +"GO:0023058" "GO:0023058" "adaptation of signaling pathway" "6/743" "20/17381" 0.000138486487268758 0.000849132193857611 0.000509522496187125 "APLNR/ADM/ADRB2/ARRB1/ARRB2/GRK2" 6 +"GO:0050849" "GO:0050849" "negative regulation of calcium-mediated signaling" "6/743" "20/17381" 0.000138486487268758 0.000849132193857611 0.000509522496187125 "CALM1/CALM3/ATP2B4/CALM2/ACTN3/CASQ2" 6 +"GO:0051900" "GO:0051900" "regulation of mitochondrial depolarization" "6/743" "20/17381" 0.000138486487268758 0.000849132193857611 0.000509522496187125 "TSPO/BOK/ALOX12/BCL2/CCK/PARP1" 6 +"GO:0060544" "GO:0060544" "regulation of necroptotic process" "6/743" "20/17381" 0.000138486487268758 0.000849132193857611 0.000509522496187125 "BIRC2/BOK/CASP8/CAV1/BIRC3/SLC25A4" 6 +"GO:0046942" "GO:0046942" "carboxylic acid transport" "28/743" "307/17381" 0.000139435165222892 0.000853937254471554 0.000512405776901314 "ANXA1/BDKRB2/AVPR1A/AKT2/AGT/AKT1/ALB/APOE/APBA1/ACACA/ABCD2/BSG/CD36/ATP1A2/ABAT/AQP9/CCK/ACACB/AGTR2/CEACAM1/ADORA2A/PLIN2/AVP/ARG1/ABCD1/AGXT/ADORA1/SLC25A20" 28 +"GO:0051098" "GO:0051098" "regulation of binding" "30/743" "339/17381" 0.00013997692089841 0.000856241803367931 0.000513788623429524 "APP/BMP2/ANXA2/ADRB2/AES/CALM3/AGER/APOE/ARRB1/AMFR/ADD1/CALM2/ADD2/CD36/KRIT1/CDK9/CDC42/BAX/BDNF/ARRB2/CAV1/BCL2/BCL3/PARP1/CDK5/BMP4/ABL1/B2M/BAK1/ANGPT1" 30 +"GO:0046632" "GO:0046632" "alpha-beta T cell differentiation" "13/743" "92/17381" 0.00014156895175558 0.000864957881151273 0.000519018713327487 "ANXA1/CD80/ATP7A/PRDM1/ADA/BCL2/TNFSF8/BRAF/BCL6/BCL3/BMX/CD86/ABL1" 13 +"GO:0002704" "GO:0002704" "negative regulation of leukocyte mediated immunity" "9/743" "47/17381" 0.00014359730946306 0.000875283953440914 0.000525214881800294 "C4BPA/ABR/BCR/ARRB2/BCL6/C4BPB/CEACAM1/BST2/ARG1" 9 +"GO:0003254" "GO:0003254" "regulation of membrane depolarization" "9/743" "47/17381" 0.00014359730946306 0.000875283953440914 0.000525214881800294 "TSPO/BOK/CAMK2D/CAV3/ALOX12/BCL2/ANK3/CCK/PARP1" 9 +"GO:0046683" "GO:0046683" "response to organophosphorus" "16/743" "131/17381" 0.000149248194464911 0.000907959623719379 0.000544821945582948 "CDO1/APP/BIRC2/CASP1/AQP8/BSG/AREG/AQP9/BRAF/HCN2/AQP1/ZFP36L1/ALDH3A1/APEX1/AANAT/AGXT" 16 +"GO:0051272" "GO:0051272" "positive regulation of cellular component movement" "38/743" "473/17381" 0.00014930891590052 0.000907959623719379 0.000544821945582948 "APP/BMP2/AIF1/BDKRB1/SCARB1/AKT2/CD74/AGT/AKT1/ACVR1B/C3AR1/APC/ATP7A/BMPR2/ALOX12/ADRA2A/BMP7/ANXA3/AAMP/BCL2/CD40/BCL6/RHOA/ACVR1/CALR/AQP1/RHOB/C5AR1/ACTN4/ATP5B/CDH13/ADAM8/ADAM10/ATP5A1/BMP4/C1QBP/ABL1/ANGPT1" 38 +"GO:0051054" "GO:0051054" "positive regulation of DNA metabolic process" "22/743" "216/17381" 0.000149838649984689 0.000910111518392914 0.000546113191814716 "ATF1/ATR/ATRX/CDK1/AKT1/AREG/CDC42/BAX/CDK2/ANXA3/CCT6A/ARRB2/CD40/APBB1/ATM/CALR/PARP1/BMP6/BMP5/BRCA1/CD28/BMP4" 22 +"GO:0071219" "GO:0071219" "cellular response to molecule of bacterial origin" "19/743" "173/17381" 0.000156742223642902 0.000950927323976574 0.000570604750720751 "CASP1/CD6/AXL/CDK4/SCARB1/AKT1/TSPO/CD80/BCR/ABCA1/CD36/PRDM1/CD40/RHOA/CD14/BMP6/ARG1/CD86/ABL1" 19 +"GO:0051052" "GO:0051052" "regulation of DNA metabolic process" "33/743" "391/17381" 0.000162754834374138 0.000986248557243753 0.000591799286828186 "ATF1/ATR/BRCA2/ATRX/ACVRL1/CDK1/AKT1/PARP4/AREG/BMPR2/CDC6/CDK9/CDC42/BAX/CDK2/ANXA3/CDKN1A/CCT6A/ARRB2/CD40/BCL6/BLM/APBB1/ATM/CALR/PARP1/BMP6/APOBEC1/BMP5/BRCA1/APAF1/CD28/BMP4" 33 +"GO:0018108" "GO:0018108" "peptidyl-tyrosine phosphorylation" "32/743" "375/17381" 0.000166612076134957 0.00100844151344842 0.000605116189102027 "APP/AXL/ABL2/DDR1/CD4/CD74/AGT/ALK/CD80/BTK/CD81/ADRA2B/BCR/CD3E/BLK/ADRA2C/AREG/CD36/CBLB/ADRA2A/ARRB2/CAV1/CD40/BTC/CCK/BMX/BST1/CD44/ABL1/CBL/ANGPT1/ADORA1" 32 +"GO:0003158" "GO:0003158" "endothelium development" "15/743" "119/17381" 0.000167265985055813 0.0010112166736727 0.000606781426358398 "ACVR2B/ACVRL1/CD34/ADD1/CDH5/BMPR2/BTG1/ALOX12/RHOA/ACVR1/CEACAM1/RHOB/BMP6/JAG1/BMP4" 15 +"GO:0050850" "GO:0050850" "positive regulation of calcium-mediated signaling" "8/743" "38/17381" 0.00016786752077784 0.00101366910154647 0.000608253007792947 "CALM1/CD4/CALM3/CD3E/CALM2/ADA/CD8A/CDH13" 8 +"GO:0046456" "GO:0046456" "icosanoid biosynthetic process" "9/743" "48/17381" 0.000170115694427949 0.00102485299029643 0.000614963909763432 "ANXA1/AVPR1A/CD74/ALOX12/ALOX15/CBR1/AVP/ALOX5/ALOX5AP" 9 +"GO:0046677" "GO:0046677" "response to antibiotic" "9/743" "48/17381" 0.000170115694427949 0.00102485299029643 0.000614963909763432 "ALPL/CDKN1B/CASP9/AOC1/ADRB3/ATP7A/CASP8/CASP3/CBL" 9 +"GO:0050730" "GO:0050730" "regulation of peptidyl-tyrosine phosphorylation" "23/743" "233/17381" 0.000170880167912095 0.00102826147551755 0.000617009174223599 "APP/CD4/CD74/AGT/CD80/CD81/ADRA2B/CD3E/ADRA2C/AREG/CD36/CBLB/ADRA2A/ARRB2/CAV1/CD40/CCK/BST1/CD44/ABL1/CBL/ANGPT1/ADORA1" 23 +"GO:0001654" "GO:0001654" "eye development" "30/743" "343/17381" 0.000172039465884307 0.00103403511724889 0.000620473652862286 "CDKN1B/ACVR2B/ACVRL1/CACNA1C/BFSP1/CDK4/CALB1/ATP2B1/ATP2B4/CASP2/SHROOM2/BBS4/BMPR2/FOXL2/PRDM1/BAX/ACTL6A/ACHE/FASLG/BMP7/BCL2/BMPR1B/ALDH1A3/AQP1/BMP6/CDKN1C/AQP5/JAG1/BMP4/BAK1" 30 +"GO:0007176" "GO:0007176" "regulation of epidermal growth factor-activated receptor activity" "7/743" "29/17381" 0.000173517219995252 0.00104050013148949 0.000624352990164047 "APP/ADRA2B/ADRA2C/CBLB/ADRA2A/CBL/ADORA1" 7 +"GO:0042168" "GO:0042168" "heme metabolic process" "7/743" "29/17381" 0.000173517219995252 0.00104050013148949 0.000624352990164047 "BLVRB/ALAS2/ALAS1/TSPO/BLVRA/ALAD/AMBP" 7 +"GO:0010660" "GO:0010660" "regulation of muscle cell apoptotic process" "11/743" "70/17381" 0.000174851574515226 0.00104548559460642 0.000627344521553815 "AGT/ARRB1/CAMK2D/ALOX12/BMP7/ARRB2/APOH/ADCYAP1/CDKN2A/BNIP3/CAMK2A" 11 +"GO:0061045" "GO:0061045" "negative regulation of wound healing" "11/743" "70/17381" 0.000174851574515226 0.00104548559460642 0.000627344521553815 "ANXA2/AGER/APOE/CD34/CD9/ALOX12/ABAT/APOH/CEACAM1/APCS/SERPING1" 11 +"GO:0001822" "GO:0001822" "kidney development" "25/743" "264/17381" 0.000174954690807567 0.00104548559460642 0.000627344521553815 "BMP2/AQP2/ACVR2B/ARG2/CALB1/AGT/ACAT1/ACTA2/CD34/BAX/AGTR1/CAT/BMP7/BCL2/AKR1B1/AGTR2/AQP1/BMP6/CDKN1C/ANGPT2/CA2/JAG1/BMP4/ANGPT1/ARL3" 25 +"GO:0002573" "GO:0002573" "myeloid leukocyte differentiation" "20/743" "189/17381" 0.000176745904439249 0.00105497122891939 0.000633036384502864 "APP/ANXA2/CD4/CDK6/CD74/RUNX1/BGLAP/CDC42/ATP6AP1/CASP8/CBFA2T3/CEACAM1/PARP1/ZFP36L1/CAMK4/C1QC/CA2/APCS/BMP4/CD86" 20 +"GO:2000147" "GO:2000147" "positive regulation of cell motility" "37/743" "460/17381" 0.000177465999279663 0.00105804901644269 0.000634883213527778 "APP/BMP2/AIF1/BDKRB1/SCARB1/AKT2/CD74/AGT/AKT1/ACVR1B/C3AR1/APC/ATP7A/BMPR2/ALOX12/ADRA2A/BMP7/ANXA3/AAMP/BCL2/CD40/RHOA/ACVR1/CALR/AQP1/RHOB/C5AR1/ACTN4/ATP5B/CDH13/ADAM8/ADAM10/ATP5A1/BMP4/C1QBP/ABL1/ANGPT1" 37 +"GO:0009411" "GO:0009411" "response to UV" "16/743" "133/17381" 0.000178368023676805 0.001062203132943 0.000637375894672128 "ATR/BRCA2/CASP9/CDKN2D/AKT1/BAX/CAT/CDKN1A/BCL2/BCL3/AQP1/CASP3/CDC25A/CCND1/ATF4/BAK1" 16 +"GO:1901016" "GO:1901016" "regulation of potassium ion transmembrane transporter activity" "10/743" "59/17381" 0.000180288231232781 0.00107204137007628 0.000643279337243838 "ATP1B3/ACTN2/ATP1B2/CAV3/CAV1/ANK3/CACNA1D/ATP1B1/CASQ2/ANK2" 10 +"GO:0032410" "GO:0032410" "negative regulation of transporter activity" "12/743" "82/17381" 0.000180641560329761 0.00107204137007628 0.000643279337243838 "CALM1/CALM3/ACTN2/CAMK2D/CAV3/CALM2/ADRA2A/ATP1A2/CAV1/ANK3/APOA2/CASQ2" 12 +"GO:1904063" "GO:1904063" "negative regulation of cation transmembrane transport" "12/743" "82/17381" 0.000180641560329761 0.00107204137007628 0.000643279337243838 "CALM1/CALM3/ACTN2/CAMK2D/CAV3/CALM2/ATP7A/ADRA2A/ATP1A2/CAV1/ANK3/CASQ2" 12 +"GO:0046777" "GO:0046777" "protein autophosphorylation" "23/743" "234/17381" 0.000182055793200161 0.001079196712269 0.000647572906421264 "CAD/CALM1/ATR/ABL2/DDR1/CAMK2B/CALM3/AKT1/ACVR1B/ALK/BTK/BCR/CAMK2D/BLK/CALM2/CAMK2G/CAV1/BMX/ATM/CAMK4/CDK5/CAMK2A/ABL1" 23 +"GO:0001890" "GO:0001890" "placenta development" "17/743" "147/17381" 0.000183970878512863 0.00108930125435248 0.000653636145505176 "BIRC2/CDKN1B/ADM/AKT1/ARNT/BSG/BMPR2/PRDM1/ANG/ASCL2/ADA/BMP7/CASP8/CCNF/ZFP36L1/CDKN1C/BMP5" 17 +"GO:0035809" "GO:0035809" "regulation of urine volume" "6/743" "21/17381" 0.000186908380776876 0.00110416766041134 0.00066255674512351 "ADM/ADCY6/BTC/AKR1B1/ADORA2A/AVPR2" 6 +"GO:0045061" "GO:0045061" "thymic T cell selection" "6/743" "21/17381" 0.000186908380776876 0.00110416766041134 0.00066255674512351 "FAS/CD74/CD3E/AIRE/CD3D/CD28" 6 +"GO:0018212" "GO:0018212" "peptidyl-tyrosine modification" "32/743" "378/17381" 0.000192573045695922 0.00113633467671197 0.000681858590653508 "APP/AXL/ABL2/DDR1/CD4/CD74/AGT/ALK/CD80/BTK/CD81/ADRA2B/BCR/CD3E/BLK/ADRA2C/AREG/CD36/CBLB/ADRA2A/ARRB2/CAV1/CD40/BTC/CCK/BMX/BST1/CD44/ABL1/CBL/ANGPT1/ADORA1" 32 +"GO:0050714" "GO:0050714" "positive regulation of protein secretion" "23/743" "235/17381" 0.000193873193242101 0.00114105758647683 0.000684692576680733 "CASP1/ARRB1/ARF1/BAD/CASP5/CD34/C5/BLK/CASR/ANG/ACHE/ABAT/CD38/APBB1/CD2/AGTR2/CD14/BMP6/ADORA2A/CD58/ADAM8/ABL1/ALOX15B" 23 +"GO:0008277" "GO:0008277" "regulation of G-protein coupled receptor protein signaling pathway" "16/743" "134/17381" 0.000194696395914791 0.00114105758647683 0.000684692576680733 "CALM1/APLNR/ADM/ADRB2/ALK/ARRB1/ATP2B4/ADA/ADRA2A/ACPP/ARRB2/C3/BICD1/CAV2/ADCYAP1/GRK2" 16 +"GO:0030260" "GO:0030260" "entry into host cell" "16/743" "134/17381" 0.000194696395914791 0.00114105758647683 0.000684692576680733 "SCARB2/AXL/CDK1/CD4/SCARB1/CD74/CD80/CD81/CAV1/ANPEP/CAV2/CDH1/GRK2/APCS/CD86/CBL" 16 +"GO:0044409" "GO:0044409" "entry into host" "16/743" "134/17381" 0.000194696395914791 0.00114105758647683 0.000684692576680733 "SCARB2/AXL/CDK1/CD4/SCARB1/CD74/CD80/CD81/CAV1/ANPEP/CAV2/CDH1/GRK2/APCS/CD86/CBL" 16 +"GO:0051806" "GO:0051806" "entry into cell of other organism involved in symbiotic interaction" "16/743" "134/17381" 0.000194696395914791 0.00114105758647683 0.000684692576680733 "SCARB2/AXL/CDK1/CD4/SCARB1/CD74/CD80/CD81/CAV1/ANPEP/CAV2/CDH1/GRK2/APCS/CD86/CBL" 16 +"GO:0051828" "GO:0051828" "entry into other organism involved in symbiotic interaction" "16/743" "134/17381" 0.000194696395914791 0.00114105758647683 0.000684692576680733 "SCARB2/AXL/CDK1/CD4/SCARB1/CD74/CD80/CD81/CAV1/ANPEP/CAV2/CDH1/GRK2/APCS/CD86/CBL" 16 +"GO:0002062" "GO:0002062" "chondrocyte differentiation" "13/743" "95/17381" 0.000196744576313341 0.00115175699368953 0.000691112765092113 "BMP2/ACVRL1/AMELX/BMPR1A/SERPINH1/RUNX1/RUNX2/BMPR2/BMPR1B/BMP6/RUNX3/NKX3-2/BMP4" 13 +"GO:0030195" "GO:0030195" "negative regulation of blood coagulation" "9/743" "49/17381" 0.00020059018853968 0.00117161876489035 0.000703030837818768 "ANXA2/APOE/CD34/CD9/ALOX12/ABAT/APOH/CEACAM1/SERPING1" 9 +"GO:1900047" "GO:1900047" "negative regulation of hemostasis" "9/743" "49/17381" 0.00020059018853968 0.00117161876489035 0.000703030837818768 "ANXA2/APOE/CD34/CD9/ALOX12/ABAT/APOH/CEACAM1/SERPING1" 9 +"GO:0043279" "GO:0043279" "response to alkaloid" "14/743" "108/17381" 0.000203042808855911 0.00117968094120233 0.00070786855358187 "AIF1/BCHE/ADA/CACNA1S/ABAT/CASP6/BLM/CASQ2/CASP7/ADORA2A/CASP3/CDK5/CCNA2/BCL2L1" 14 +"GO:0008625" "GO:0008625" "extrinsic apoptotic signaling pathway via death domain receptors" "12/743" "83/17381" 0.000203105048870775 0.00117968094120233 0.00070786855358187 "BID/FAS/BAD/BAX/FASLG/CASP8/BCL2/ATF3/BMPR1B/BMP5/BRCA1/BCL2L1" 12 +"GO:1901186" "GO:1901186" "positive regulation of ERBB signaling pathway" "8/743" "39/17381" 0.000203361913587093 0.00117968094120233 0.00070786855358187 "AGT/AKT1/ADRA2B/ADRA2C/ADRA2A/FASLG/CBL/ADORA1" 8 +"GO:0001976" "GO:0001976" "neurological system process involved in regulation of systemic arterial blood pressure" "5/743" "14/17381" 0.000204250072138606 0.00117968094120233 0.00070786855358187 "AGT/CALCA/ASIC2/ADRA1A/AGTR2" 5 +"GO:0009415" "GO:0009415" "response to water" "5/743" "14/17381" 0.000204250072138606 0.00117968094120233 0.00070786855358187 "AQP2/AVPR1A/ATP2B4/CD9/AKR1B1" 5 +"GO:0019627" "GO:0019627" "urea metabolic process" "5/743" "14/17381" 0.000204250072138606 0.00117968094120233 0.00070786855358187 "ASL/CAD/ARG2/ASS1/ARG1" 5 +"GO:0060547" "GO:0060547" "negative regulation of necrotic cell death" "5/743" "14/17381" 0.000204250072138606 0.00117968094120233 0.00070786855358187 "BIRC2/BOK/CAV1/BIRC3/SLC25A4" 5 +"GO:0097340" "GO:0097340" "inhibition of cysteine-type endopeptidase activity" "5/743" "14/17381" 0.000204250072138606 0.00117968094120233 0.00070786855358187 "BIRC2/CAST/XIAP/BIRC3/BIRC5" 5 +"GO:0097341" "GO:0097341" "zymogen inhibition" "5/743" "14/17381" 0.000204250072138606 0.00117968094120233 0.00070786855358187 "BIRC2/CAST/XIAP/BIRC3/BIRC5" 5 +"GO:2000105" "GO:2000105" "positive regulation of DNA-dependent DNA replication" "5/743" "14/17381" 0.000204250072138606 0.00117968094120233 0.00070786855358187 "ATRX/CDK2/BMP6/BMP5/BMP4" 5 +"GO:0014823" "GO:0014823" "response to activity" "10/743" "60/17381" 0.0002081814057333 0.00119704308296647 0.000718286721535947 "CDK1/AGT/BGLAP/CAPN3/ALAD/CAT/BMP6/ANGPT2/ADSL/CBL" 10 +"GO:0048857" "GO:0048857" "neural nucleus development" "10/743" "60/17381" 0.0002081814057333 0.00119704308296647 0.000718286721535947 "ATP5F1/CASP5/ASCL1/CDC42/PHOX2A/ACTB/ATP5J/BCL2/ALDH1A3/RHOA" 10 +"GO:0060135" "GO:0060135" "maternal process involved in female pregnancy" "10/743" "60/17381" 0.0002081814057333 0.00119704308296647 0.000718286721535947 "AKT1/ADCY7/AR/BSG/AGRP/BMPR2/PRDM1/AKR1B1/ANGPT2/ARG1" 10 +"GO:1902110" "GO:1902110" "positive regulation of mitochondrial membrane permeability involved in apoptotic process" "10/743" "60/17381" 0.0002081814057333 0.00119704308296647 0.000718286721535947 "BNIP3L/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BNIP3/BAK1" 10 +"GO:0015849" "GO:0015849" "organic acid transport" "28/743" "315/17381" 0.000214554694993643 0.00123232025148957 0.000739454816556164 "ANXA1/BDKRB2/AVPR1A/AKT2/AGT/AKT1/ALB/APOE/APBA1/ACACA/ABCD2/BSG/CD36/ATP1A2/ABAT/AQP9/CCK/ACACB/AGTR2/CEACAM1/ADORA2A/PLIN2/AVP/ARG1/ABCD1/AGXT/ADORA1/SLC25A20" 28 +"GO:0034103" "GO:0034103" "regulation of tissue remodeling" "12/743" "84/17381" 0.000227906139408457 0.0013046618046889 0.000782863427171574 "AGT/CALCA/AGER/BGLAP/ABR/BCR/BAX/ATP6AP1/CD38/CEACAM1/CA2/ADAM8" 12 +"GO:0042475" "GO:0042475" "odontogenesis of dentin-containing tooth" "12/743" "84/17381" 0.000227906139408457 0.0013046618046889 0.000782863427171574 "BMP2/ADM/ACVR2B/AMELX/BMPR1A/RUNX2/BSG/BAX/BMP7/CA2/AMBN/BMP4" 12 +"GO:1901989" "GO:1901989" "positive regulation of cell cycle phase transition" "12/743" "84/17381" 0.000227906139408457 0.0013046618046889 0.000782863427171574 "ANXA1/APP/CDC25C/AIF1/CDK1/CDK4/CCND2/CDC6/CDC25B/CDC25A/APEX1/CCND1" 12 +"GO:0021537" "GO:0021537" "telencephalon development" "23/743" "238/17381" 0.000233495248011422 0.00133518000934708 0.000801175901871119 "BMP2/BCL2A1/BBS2/AVPR1A/CDK6/ALK/BAD/ATP1A3/CDH2/ATP2B4/ASCL1/BBS4/ATIC/BAX/ANXA3/ATOH1/ALDH1A3/AQP1/CASP3/CDK5/AVPR2/BMP4/BNIP3" 23 +"GO:0071385" "GO:0071385" "cellular response to glucocorticoid stimulus" "10/743" "61/17381" 0.000239608200043819 0.00136862299693903 0.000821243395061305 "ANXA1/CASP9/KLF9/ATP2B1/ZFP36L2/AGTR2/AQP1/ZFP36L1/ADCYAP1/ARG1" 10 +"GO:0043534" "GO:0043534" "blood vessel endothelial cell migration" "13/743" "97/17381" 0.000242998877053825 0.00138645996554967 0.000831946483269059 "ACVRL1/SCARB1/AKT1/APOE/APOA1/CD40/RHOA/AGTR2/ANGPT2/ATP5B/ATP5A1/ABL1/ANGPT1" 13 +"GO:0086004" "GO:0086004" "regulation of cardiac muscle cell contraction" "8/743" "40/17381" 0.000244787282406194 0.00139512575600447 0.000837146398212698 "CACNA1C/ATP2A2/ATP1A1/CAMK2D/CAV3/ATP1A2/CAV1/ANK2" 8 +"GO:0034101" "GO:0034101" "erythrocyte homeostasis" "14/743" "110/17381" 0.000246768704449203 0.00140282139708797 0.000841764174199749 "ALAS2/AXL/CDK6/ACVR1B/ARNT/AMPD3/ADD1/ADAR/BCL6/ZFP36L1/ACVR2A/CASP3/BMP4/B2M" 14 +"GO:0070252" "GO:0070252" "actin-mediated cell contraction" "14/743" "110/17381" 0.000246768704449203 0.00140282139708797 0.000841764174199749 "CACNA1C/ACTA1/ACTN2/ATP1A1/CAMK2D/CAV3/CACNA2D1/ACTN3/ATP1A2/CAV1/CACNA1D/ACTC1/ANK2/CACNB2" 14 +"GO:0010884" "GO:0010884" "positive regulation of lipid storage" "6/743" "22/17381" 0.000247764011002591 0.00140282139708797 0.000841764174199749 "APOC4/SCARB1/CD36/C3/ACACB/APOB" 6 +"GO:0015874" "GO:0015874" "norepinephrine transport" "6/743" "22/17381" 0.000247764011002591 0.00140282139708797 0.000841764174199749 "AGT/ADRA2B/ADRA2C/ADRA2A/AGTR2/ADORA2A" 6 +"GO:0051004" "GO:0051004" "regulation of lipoprotein lipase activity" "6/743" "22/17381" 0.000247764011002591 0.00140282139708797 0.000841764174199749 "APOC2/APOC3/APOA4/APOA1/APOH/APOC1" 6 +"GO:0071402" "GO:0071402" "cellular response to lipoprotein particle stimulus" "6/743" "22/17381" 0.000247764011002591 0.00140282139708797 0.000841764174199749 "APOE/CD81/CD9/CASR/CD36/CDH13" 6 +"GO:0000910" "GO:0000910" "cytokinesis" "16/743" "137/17381" 0.000251716851859969 0.00142364449002769 0.000854259088854653 "BRCA2/CXCR5/SEPT7/ARF1/APC/BBS4/CDC6/CDC42/RHOC/CDC25B/ANK3/RHOA/RHOB/BCL2L1/ANXA11/ARL3" 16 +"GO:2001257" "GO:2001257" "regulation of cation channel activity" "17/743" "151/17381" 0.000254432684424169 0.00143743356102082 0.000862533232649159 "APP/CASQ1/CALM1/CACNB4/ADRB2/CALM3/ACTN2/CAMK2D/CALM2/CACNA2D1/CAV1/ANK3/CACNB1/CASQ2/ANK2/CACNB2/CACNB3" 17 +"GO:0045621" "GO:0045621" "positive regulation of lymphocyte differentiation" "12/743" "85/17381" 0.00025523830701941 0.0014404124741826 0.000864320732029226 "ANXA1/AXL/CD74/CD80/BTK/BAD/CD27/PRDM1/ADA/BCL6/ADAM8/CD86" 12 +"GO:0002822" "GO:0002822" "regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains" "15/743" "124/17381" 0.000264674199430992 0.00149203592816491 0.000895297429562466 "ANXA1/C4BPA/CD4/AGER/CD80/BTK/ADA/CD40/BCL6/C4BPB/C3/CEACAM1/ARG1/CD28/B2M" 15 +"GO:0000075" "GO:0000075" "cell cycle checkpoint" "22/743" "225/17381" 0.000268538233292029 0.00151052756226766 0.000906393350356391 "CDKN1B/ATR/CDC25C/CDK1/CCNB1/BUB1B/AKT1/BUB1/APC/CDC5L/CASP2/CDC6/BAX/CDK2/CDKN2B/CDKN1A/BLM/ATM/BRCA1/BCL2L1/CCND1/CCNG2" 22 +"GO:0072659" "GO:0072659" "protein localization to plasma membrane" "22/743" "225/17381" 0.000268538233292029 0.00151052756226766 0.000906393350356391 "BBS2/ANXA2/AKT2/ATP1B3/AKT1/AR/ACTN2/CDH2/BSG/CAV3/CALCR/ANK1/BBS1/RHOG/ANK3/ATP1B1/ARF6/CDH1/ANK2/BCL2L1/CACNB2/CACNB3" 22 +"GO:0051048" "GO:0051048" "negative regulation of secretion" "21/743" "210/17381" 0.000270410624931875 0.00151899137761335 0.000911472069963769 "ANXA1/ANXA4/ARG2/CD74/CD34/ABR/ADRA2B/BCR/ADRA2C/APOA1/ADA/ADRA2A/ABAT/BRAF/APOA2/AGTR2/CEACAM1/ASIC1/AVPR2/ANGPT1/ADORA1" 21 +"GO:0010765" "GO:0010765" "positive regulation of sodium ion transport" "7/743" "31/17381" 0.00027135346895019 0.00151899137761335 0.000911472069963769 "ATP1B3/AKT1/ARF1/ATP1B2/ANK3/ATP1B1/ACTN4" 7 +"GO:0071470" "GO:0071470" "cellular response to osmotic stress" "7/743" "31/17381" 0.00027135346895019 0.00151899137761335 0.000911472069963769 "BDKRB2/TSPO/BAD/CAPN3/AQP1/ZFP36L1/CASP3" 7 +"GO:2000404" "GO:2000404" "regulation of T cell migration" "7/743" "31/17381" 0.00027135346895019 0.00151899137761335 0.000911472069963769 "APP/AIF1/AIRE/RHOA/APOD/ADAM8/ADAM10" 7 +"GO:2000117" "GO:2000117" "negative regulation of cysteine-type endopeptidase activity" "14/743" "111/17381" 0.00027151053609514 0.00151899137761335 0.000911472069963769 "BIRC2/CDKN2D/AKT1/ARRB1/CAST/CD27/ARRB2/XIAP/AQP1/BIRC3/ADORA2A/BIRC5/AVP/CD44" 14 +"GO:0030858" "GO:0030858" "positive regulation of epithelial cell differentiation" "10/743" "62/17381" 0.000274914038637423 0.00153377787088401 0.000920344717845476 "ACVRL1/BAD/ADD1/CDH5/BTG1/ALOX12/ATOH1/BMP6/BMP4/ALOX15B" 10 +"GO:1902686" "GO:1902686" "mitochondrial outer membrane permeabilization involved in programmed cell death" "10/743" "62/17381" 0.000274914038637423 0.00153377787088401 0.000920344717845476 "BNIP3L/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BNIP3/BAK1" 10 +"GO:0035725" "GO:0035725" "sodium ion transmembrane transport" "17/743" "152/17381" 0.00027533906126594 0.00153377787088401 0.000920344717845476 "ATP1B3/ASIC2/ARF1/ATP1A3/ATP2B4/ATP1B2/ATP1A1/CAMK2D/CAV3/SHROOM2/FXYD2/ATP1A2/ANK3/ATP1B1/HCN2/ASIC1/ACTN4" 17 +"GO:0038127" "GO:0038127" "ERBB signaling pathway" "17/743" "152/17381" 0.00027533906126594 0.00153377787088401 0.000920344717845476 "APP/AGT/AKT1/CAMLG/ADRA2B/ADRA2C/AREG/CBLB/CDC42/ADRA2A/FASLG/BTC/CEACAM1/CDH13/ABL1/CBL/ADORA1" 17 +"GO:0019884" "GO:0019884" "antigen processing and presentation of exogenous antigen" "19/743" "181/17381" 0.000281966892840429 0.00156732402840947 0.000940474118242144 "AP2B1/AP1B1/CD74/CD1E/ARF1/AP1G1/CD1A/CAPZB/CD36/CANX/CD1B/CD1C/CAPZA2/AP2A1/CAPZA1/CALR/AP2A2/CD1D/B2M" 19 +"GO:0051783" "GO:0051783" "regulation of nuclear division" "19/743" "181/17381" 0.000281966892840429 0.00156732402840947 0.000940474118242144 "CDKN1B/CDC25C/ATRX/CCNB1/BUB1B/BUB1/APC/CDC20/CDC6/CDC42/BMP7/BTC/ATM/CALR/CAV2/CDKN1C/CD28/BMP4/CDC27" 19 +"GO:0032413" "GO:0032413" "negative regulation of ion transmembrane transporter activity" "11/743" "74/17381" 0.000289299517471939 0.00160463558726397 0.000962862950913546 "CALM1/CALM3/ACTN2/CAMK2D/CAV3/CALM2/ADRA2A/ATP1A2/CAV1/ANK3/CASQ2" 11 +"GO:0051289" "GO:0051289" "protein homotetramerization" "11/743" "74/17381" 0.000289299517471939 0.00160463558726397 0.000962862950913546 "ALDOA/CD79A/CD247/ACTN2/ACACA/CDA/CAT/ACPP/ACADL/ALDH1A3/ACACB" 11 +"GO:0006000" "GO:0006000" "fructose metabolic process" "5/743" "15/17381" 0.000295632031757347 0.00163101893853334 0.000978694303315198 "ALDOC/ALDOA/ALDH1A1/ALDOB/AKR1B1" 5 +"GO:0014048" "GO:0014048" "regulation of glutamate secretion" "5/743" "15/17381" 0.000295632031757347 0.00163101893853334 0.000978694303315198 "AVPR1A/CCK/ADORA2A/AVP/ADORA1" 5 +"GO:0034310" "GO:0034310" "primary alcohol catabolic process" "5/743" "15/17381" 0.000295632031757347 0.00163101893853334 0.000978694303315198 "ALDH1B1/ADH7/ALDH3B1/ALDH3B2/ALDH2" 5 +"GO:0034656" "GO:0034656" "nucleobase-containing small molecule catabolic process" "5/743" "15/17381" 0.000295632031757347 0.00163101893853334 0.000978694303315198 "ENTPD5/ENTPD3/ENTPD6/ENTPD2/ENTPD1" 5 +"GO:0071941" "GO:0071941" "nitrogen cycle metabolic process" "5/743" "15/17381" 0.000295632031757347 0.00163101893853334 0.000978694303315198 "ASL/CAD/ARG2/ASS1/ARG1" 5 +"GO:0016125" "GO:0016125" "sterol metabolic process" "17/743" "153/17381" 0.000297720411463367 0.00164079140502974 0.00098455828016023 "APP/SCARB1/ACAT2/APOE/APOA4/ACACA/ACLY/ABCA1/APOA1/CAT/ACADVL/ACADL/ACACB/APOA2/APOC1/APOB/APOF" 17 +"GO:0032680" "GO:0032680" "regulation of tumor necrosis factor production" "14/743" "112/17381" 0.000298351504115271 0.00164252024871971 0.00098559567428897 "AXL/BPI/ARG2/AZU1/ACP5/TSPO/CD34/CD36/TNFRSF8/ARRB2/BCL3/CD2/CD14/ANGPT1" 14 +"GO:0070371" "GO:0070371" "ERK1 and ERK2 cascade" "26/743" "290/17381" 0.000311640681890293 0.0017138581602362 0.00102840204885773 "APP/BMP2/CD4/CD74/AGT/AGER/ARRB1/ADRA1A/CD36/CALCR/ATP6AP1/ALOX15/ZFP36L2/ARAF/ARRB2/BRAF/ATF3/CEACAM1/C5AR1/ZFP36L1/ADCYAP1/AVP/CD44/BMP4/ABL1/ANGPT1" 26 +"GO:0007586" "GO:0007586" "digestion" "18/743" "168/17381" 0.00031440114897901 0.00172390652498057 0.00103443157868145 "SCARB1/AMY1A/AMY2A/APOA4/AMY1C/ALPI/SERPINA3/CCKAR/ACO1/CD36/AMY2B/APOA1/ADRA2A/CCKBR/APOA2/AQP1/AQP5/AMY1B" 18 +"GO:0032835" "GO:0032835" "glomerulus development" "10/743" "63/17381" 0.00031446719991916 0.00172390652498057 0.00103443157868145 "ACTA2/CD34/BMP7/BCL2/AGTR2/AQP1/ANGPT2/JAG1/BMP4/ANGPT1" 10 +"GO:0086003" "GO:0086003" "cardiac muscle cell contraction" "10/743" "63/17381" 0.00031446719991916 0.00172390652498057 0.00103443157868145 "CACNA1C/ATP1A1/CAMK2D/CAV3/CACNA2D1/ATP1A2/CAV1/CACNA1D/ANK2/CACNB2" 10 +"GO:0001501" "GO:0001501" "skeletal system development" "38/743" "491/17381" 0.000315170609270199 0.00172429534859619 0.00103466489262319 "BMP2/ALPL/BBS2/ANXA2/ACVR2B/ACVRL1/AES/AMELX/ARSE/BMPR1A/SERPINH1/ACP5/RUNX1/RUNX2/ACP2/BGLAP/BMP8B/ACAN/ATP7A/BMPR2/ALX3/BMP1/ATP6AP1/BMP7/CDH11/BMPR1B/RHOA/BMP6/AEBP1/CDKN1C/BMP5/ACVR2A/RUNX3/NKX3-2/CD44/AHSG/BMP4/BMP3" 38 +"GO:0030072" "GO:0030072" "peptide hormone secretion" "23/743" "243/17381" 0.000315537718863882 0.00172429534859619 0.00103466489262319 "ANXA1/SLC25A6/ACVR2B/CACNA1C/ARRB1/ADCY5/BAD/SLC25A5/BLK/ADRA2C/CASR/ARL2/ADRA2A/CAMK2G/ABAT/CD38/CACNA1D/AQP1/ARNTL/ADCYAP1/CACNA1E/CACNA1A/SLC25A4" 23 +"GO:0043122" "GO:0043122" "regulation of I-kappaB kinase/NF-kappaB signaling" "23/743" "243/17381" 0.000315537718863882 0.00172429534859619 0.00103466489262319 "APP/BIRC2/CASP1/CD4/CD74/RHOH/AKT1/AGER/CD27/CD36/CAPN3/CASP10/FASLG/BMP7/RHOC/CASP8/CD40/RHOA/BCL3/BST2/BIRC3/ABL1/ANGPT1" 23 +"GO:0010043" "GO:0010043" "response to zinc ion" "9/743" "52/17381" 0.000320395490041343 0.00174715138141618 0.00104837967458484 "TSPO/BGLAP/ATP7A/ALAD/PARP1/APOBEC1/CA2/ARG1/AANAT" 9 +"GO:0032663" "GO:0032663" "regulation of interleukin-2 production" "9/743" "52/17381" 0.000320395490041343 0.00174715138141618 0.00104837967458484 "ANXA1/CD4/RUNX1/CD80/CD34/CD3E/CD28/CD86/ABL1" 9 +"GO:0001783" "GO:0001783" "B cell apoptotic process" "6/743" "23/17381" 0.000323174732965635 0.00175860067623256 0.00105524983369154 "CD74/BTK/BAX/ADA/BCL6/BAK1" 6 +"GO:0051953" "GO:0051953" "negative regulation of amine transport" "6/743" "23/17381" 0.000323174732965635 0.00175860067623256 0.00105524983369154 "ADRA2B/ADRA2C/ADRA2A/ABAT/AGTR2/ADORA1" 6 +"GO:0031398" "GO:0031398" "positive regulation of protein ubiquitination" "19/743" "183/17381" 0.000324423045564251 0.00176353913949054 0.00105821316277592 "BIRC2/ADRB2/CDK1/CCNB1/BUB1B/ARRB1/CAV3/CDC20/CDK9/ARRB2/XIAP/CAV1/BMI1/BIRC3/BRCA1/AVPR2/PTTG1IP/CDC27/ANGPT1" 19 +"GO:0007200" "GO:0007200" "phospholipase C-activating G-protein coupled receptor signaling pathway" "14/743" "113/17381" 0.000327435181492397 0.00177804518806207 0.00106691752957704 "AGT/CALCA/C3AR1/ADRA1D/ADRA1A/ACTN2/CCKAR/CASR/AGTR1/ADRA1B/ADRA2A/CCKBR/BICD1/C5AR1" 14 +"GO:0006260" "GO:0006260" "DNA replication" "26/743" "291/17381" 0.000328728453477656 0.00178132957774541 0.00106888833040406 "ATF1/ATR/CDC25C/BRCA2/ATRX/ACVRL1/CDK1/AREG/CDC34/CDC6/CDK9/CDC42/CDK2/ACHE/CCNE1/BARD1/BCL6/BLM/ATM/CALR/PARP1/BMP6/BMP5/BRCA1/CDC25A/BMP4" 26 +"GO:1903320" "GO:1903320" "regulation of protein modification by small protein conjugation or removal" "26/743" "291/17381" 0.000328728453477656 0.00178132957774541 0.00106888833040406 "BIRC2/ADRB2/CDK1/CCNB1/BUB1B/TSPO/ARRB1/ARNT/ADGRB1/CAV3/CDC20/CAPN3/CDK9/CDK2/ARRB2/XIAP/CAV1/BMI1/BIRC3/BRCA1/CDK5/AVPR2/PTTG1IP/ABL1/CDC27/ANGPT1" 26 +"GO:0010639" "GO:0010639" "negative regulation of organelle organization" "29/743" "340/17381" 0.000334169045081599 0.00180772036522847 0.00108472414491207 "ATRX/CCNB1/BUB1B/AKT1/TSPO/BUB1/SLC25A5/BOK/APC/ADD1/CAV3/BBS4/ADD2/CAPZB/CAPG/BMP7/ARRB2/CAPZA2/CAPZA1/ATM/ARHGAP6/PARP1/CCNF/APOBEC1/BRCA1/AVP/BCL2L1/BMP4/BNIP3" 29 +"GO:0035587" "GO:0035587" "purinergic receptor signaling pathway" "7/743" "32/17381" 0.000334646591282874 0.00180772036522847 0.00108472414491207 "ADCY5/ADORA3/ADA/ACPP/ADORA2B/ADORA2A/ADORA1" 7 +"GO:0051954" "GO:0051954" "positive regulation of amine transport" "7/743" "32/17381" 0.000334646591282874 0.00180772036522847 0.00108472414491207 "AVPR1A/AGT/ABAT/CCK/ADORA2A/GRK2/AVP" 7 +"GO:0055001" "GO:0055001" "muscle cell development" "18/743" "169/17381" 0.000338178105057827 0.00182489227703259 0.00109502816521661 "CASQ1/ADM/CDK1/AGT/CCNB1/ATP2A2/ACTA1/ACTN2/CAV3/CAPN3/ACTG1/BCL2/ACTC1/AGTR2/CASQ2/CAV2/ANK2/BMP4" 18 +"GO:0002695" "GO:0002695" "negative regulation of leukocyte activation" "17/743" "155/17381" 0.00034725414181208 0.00186996897385797 0.00112207647554152 "ANXA1/AXL/BPI/ARG2/FAS/CD74/BTK/ABR/BCR/PRDM1/BCL6/CEACAM1/ATM/ADORA2A/CASP3/ARG1/BMP4" 17 +"GO:0048167" "GO:0048167" "regulation of synaptic plasticity" "17/743" "155/17381" 0.00034725414181208 0.00186996897385797 0.00112207647554152 "APP/CAMK2B/CALB1/AGT/AGER/APOE/ARF1/ADGRB1/CDC20/BRAF/CD38/ADORA2A/CDK5/CBLN1/CAMK2A/ABL1/ADORA1" 17 +"GO:0007595" "GO:0007595" "lactation" "8/743" "42/17381" 0.000348397799291325 0.0018741773506576 0.0011246017156247 "CDO1/DDR1/SERPINC1/ATP7A/APRT/CAV1/ATP7B/CCND1" 8 +"GO:0070374" "GO:0070374" "positive regulation of ERK1 and ERK2 cascade" "20/743" "199/17381" 0.000351089432436348 0.00188669554813925 0.00113211327068615 "APP/BMP2/CD4/CD74/AGER/ARRB1/ADRA1A/CD36/CALCR/ATP6AP1/ALOX15/ARAF/ARRB2/BRAF/C5AR1/ADCYAP1/CD44/BMP4/ABL1/ANGPT1" 20 +"GO:0001818" "GO:0001818" "negative regulation of cytokine production" "23/743" "245/17381" 0.000354862591637952 0.00190499368436349 0.00114309308291325 "ANXA1/AXL/BPI/ANXA4/ARG2/AGER/ACP5/CDH3/TSPO/BTK/ARRB1/CD34/APOA1/ARRB2/BCL6/BCL3/APOA2/CEACAM1/BST2/APOD/ARG1/C1QBP/ANGPT1" 23 +"GO:0015914" "GO:0015914" "phospholipid transport" "10/743" "64/17381" 0.000358659410903911 0.00191741988783857 0.00115054943689271 "APOC2/APOC3/SCARB1/APOE/APOA4/ABCA1/APOA1/APOA2/ABCA4/APOC1" 10 +"GO:0035794" "GO:0035794" "positive regulation of mitochondrial membrane permeability" "10/743" "64/17381" 0.000358659410903911 0.00191741988783857 0.00115054943689271 "BNIP3L/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BNIP3/BAK1" 10 +"GO:0046889" "GO:0046889" "positive regulation of lipid biosynthetic process" "10/743" "64/17381" 0.000358659410903911 0.00191741988783857 0.00115054943689271 "ANXA1/APOC2/AVPR1A/SCARB1/AKT1/APOE/APOA4/APOA1/BMP6/AVP" 10 +"GO:0071384" "GO:0071384" "cellular response to corticosteroid stimulus" "10/743" "64/17381" 0.000358659410903911 0.00191741988783857 0.00115054943689271 "ANXA1/CASP9/KLF9/ATP2B1/ZFP36L2/AGTR2/AQP1/ZFP36L1/ADCYAP1/ARG1" 10 +"GO:1903409" "GO:1903409" "reactive oxygen species biosynthetic process" "13/743" "101/17381" 0.000363878138053967 0.00194331203759472 0.00116608604340797 "AIF1/ARG2/AGT/AKT1/ACP5/TSPO/CD34/ADGRB1/ATP2B4/CD36/CAV1/ASS1/AGTR2" 13 +"GO:0043535" "GO:0043535" "regulation of blood vessel endothelial cell migration" "11/743" "76/17381" 0.000366891997305978 0.00195738771758602 0.00117453216717595 "ACVRL1/AKT1/APOE/CD40/RHOA/AGTR2/ANGPT2/ATP5B/ATP5A1/ABL1/ANGPT1" 11 +"GO:0002011" "GO:0002011" "morphogenesis of an epithelial sheet" "9/743" "53/17381" 0.000371509917422897 0.00197794631961264 0.00118686837383316 "ACVRL1/DDR1/BMP7/RHOC/RHOA/CEACAM1/BMP5/CD44/JAG1" 9 +"GO:0044273" "GO:0044273" "sulfur compound catabolic process" "9/743" "53/17381" 0.000371509917422897 0.00197794631961264 0.00118686837383316 "CDO1/AHCY/ACAT1/ACAN/BLMH/BGN/CBS/ARSB/AGXT" 9 +"GO:1903322" "GO:1903322" "positive regulation of protein modification by small protein conjugation or removal" "20/743" "200/17381" 0.000374851977475214 0.0019936885749581 0.00119631452756194 "BIRC2/ADRB2/CDK1/CCNB1/BUB1B/ARRB1/ARNT/CAV3/CDC20/CDK9/ARRB2/XIAP/CAV1/BMI1/BIRC3/BRCA1/AVPR2/PTTG1IP/CDC27/ANGPT1" 20 +"GO:0007088" "GO:0007088" "regulation of mitotic nuclear division" "17/743" "157/17381" 0.000403764150615905 0.00214305587634596 0.00128594250398588 "CDKN1B/CDC25C/ATRX/CCNB1/BUB1B/BUB1/APC/CDC6/CDC42/BMP7/BTC/ATM/CAV2/CDKN1C/CD28/BMP4/CDC27" 17 +"GO:0022408" "GO:0022408" "negative regulation of cell-cell adhesion" "17/743" "157/17381" 0.000403764150615905 0.00214305587634596 0.00128594250398588 "ANXA1/BMP2/ARG2/CD74/CD9/APOA1/ALOX12/ABAT/BCL6/ASS1/CEACAM1/ADORA2A/CDH1/CASP3/ARG1/BMP4/ABL1" 17 +"GO:0006720" "GO:0006720" "isoprenoid metabolic process" "15/743" "129/17381" 0.000407524608784021 0.00215884058440761 0.00129541413150317 "APOC2/APOC3/APOE/APOA4/ALDH3A2/OPN1SW/APOA1/ADH7/ADH5/ADH4/ALDH1A1/ALDH1A3/APOA2/ABCA4/APOB" 15 +"GO:0019433" "GO:0019433" "triglyceride catabolic process" "7/743" "33/17381" 0.000409241084696399 0.00215884058440761 0.00129541413150317 "APOC2/APOC3/APOE/APOA4/AADAC/APOA1/APOB" 7 +"GO:0032801" "GO:0032801" "receptor catabolic process" "7/743" "33/17381" 0.000409241084696399 0.00215884058440761 0.00129541413150317 "ANXA2/AP2B1/APOE/CAPN1/AP2A1/CDK5/AP2A2" 7 +"GO:0055090" "GO:0055090" "acylglycerol homeostasis" "7/743" "33/17381" 0.000409241084696399 0.00215884058440761 0.00129541413150317 "APOC2/APOC3/APOC4/SCARB1/APOE/APOA4/APOA1" 7 +"GO:0070328" "GO:0070328" "triglyceride homeostasis" "7/743" "33/17381" 0.000409241084696399 0.00215884058440761 0.00129541413150317 "APOC2/APOC3/APOC4/SCARB1/APOE/APOA4/APOA1" 7 +"GO:0098901" "GO:0098901" "regulation of cardiac muscle cell action potential" "7/743" "33/17381" 0.000409241084696399 0.00215884058440761 0.00129541413150317 "CACNA1C/ATP2A2/CAMK2D/CAV3/CAV1/ANK3/ANK2" 7 +"GO:0031016" "GO:0031016" "pancreas development" "11/743" "77/17381" 0.000411811684111347 0.00216943533082088 0.00130177151811271 "ANXA1/ACVR2B/CDK6/AKT1/BAD/ARNTL/BMP6/BMP5/NKX3-2/BMP4/BAK1" 11 +"GO:0010744" "GO:0010744" "positive regulation of macrophage derived foam cell differentiation" "5/743" "16/17381" 0.000414948189600291 0.00216943533082088 0.00130177151811271 "AGT/CD36/AGTR1/APOB/ALOX15B" 5 +"GO:0033539" "GO:0033539" "fatty acid beta-oxidation using acyl-CoA dehydrogenase" "5/743" "16/17381" 0.000414948189600291 0.00216943533082088 0.00130177151811271 "ACOX1/ACADM/ACADVL/ACADL/ACADS" 5 +"GO:0045986" "GO:0045986" "negative regulation of smooth muscle contraction" "5/743" "16/17381" 0.000414948189600291 0.00216943533082088 0.00130177151811271 "ADRB2/CALCA/ADRA2C/ADORA2B/ADORA1" 5 +"GO:0046885" "GO:0046885" "regulation of hormone biosynthetic process" "5/743" "16/17381" 0.000414948189600291 0.00216943533082088 0.00130177151811271 "BMP2/ARNT/ATP1A1/BMP6/BMP5" 5 +"GO:0071404" "GO:0071404" "cellular response to low-density lipoprotein particle stimulus" "5/743" "16/17381" 0.000414948189600291 0.00216943533082088 0.00130177151811271 "CD81/CD9/CASR/CD36/CDH13" 5 +"GO:1902001" "GO:1902001" "fatty acid transmembrane transport" "5/743" "16/17381" 0.000414948189600291 0.00216943533082088 0.00130177151811271 "AKT2/AKT1/ACACA/ACACB/SLC25A20" 5 +"GO:0002068" "GO:0002068" "glandular epithelial cell development" "6/743" "24/17381" 0.000415441625670241 0.00216943533082088 0.00130177151811271 "CDK6/BAD/ARNTL/BMP6/BMP5/BMP4" 6 +"GO:0010661" "GO:0010661" "positive regulation of muscle cell apoptotic process" "6/743" "24/17381" 0.000415441625670241 0.00216943533082088 0.00130177151811271 "AGT/ARRB1/CAMK2D/CDKN2A/BNIP3/CAMK2A" 6 +"GO:0032461" "GO:0032461" "positive regulation of protein oligomerization" "6/743" "24/17381" 0.000415441625670241 0.00216943533082088 0.00130177151811271 "BID/FAS/BAX/RHOC/CCK/BIK" 6 +"GO:0050796" "GO:0050796" "regulation of insulin secretion" "18/743" "172/17381" 0.000419117396667628 0.00218642391910784 0.00131196553498462 "SLC25A6/CACNA1C/ARRB1/ADCY5/BAD/SLC25A5/BLK/ADRA2C/CASR/ARL2/ADRA2A/ABAT/CD38/CACNA1D/ARNTL/CACNA1E/CACNA1A/SLC25A4" 18 +"GO:0010001" "GO:0010001" "glial cell differentiation" "19/743" "187/17381" 0.000426300027303211 0.00222165422084 0.00133310550754701 "APP/BMP2/CDK1/CDK6/AKT2/AKT1/BIN1/AGER/CDH2/BOK/CD9/ASPA/ASCL1/MYRF/ADORA2A/CDK5/BNIP3/CDKN2C/ABL1" 19 +"GO:0072001" "GO:0072001" "renal system development" "25/743" "280/17381" 0.000429148047868904 0.0022342466274865 0.00134066159188104 "BMP2/AQP2/ACVR2B/ARG2/CALB1/AGT/ACAT1/ACTA2/CD34/BAX/AGTR1/CAT/BMP7/BCL2/AKR1B1/AGTR2/AQP1/BMP6/CDKN1C/ANGPT2/CA2/JAG1/BMP4/ANGPT1/ARL3" 25 +"GO:0034754" "GO:0034754" "cellular hormone metabolic process" "14/743" "116/17381" 0.000429686693730603 0.00223480265332248 0.00134099523565753 "BMP2/ADM/SCARB1/TSPO/ASMT/AFP/ADH7/ADH4/ALDH1A1/ALDH1A3/AKR1B1/BMP6/BMP5/AANAT" 14 +"GO:0051222" "GO:0051222" "positive regulation of protein transport" "37/743" "482/17381" 0.000439565722280064 0.00228388816546117 0.00137044903902577 "APP/CASP1/CDK1/AKT2/BMPR1A/AGER/ARRB1/ARF1/BAD/CASP5/CD34/C5/BLK/CD27/CASR/ANG/CDC42/ACTL6A/ACHE/ABAT/ANK3/CD38/RHOA/APBB1/CD2/AGTR2/CD14/PARP1/BMP6/ADORA2A/CDH1/CDK5/CD58/ADAM8/BMP4/ABL1/ALOX15B" 37 +"GO:0001952" "GO:0001952" "regulation of cell-matrix adhesion" "13/743" "103/17381" 0.000441401473698808 0.00229112600440455 0.0013747921104487 "ACVRL1/DDR1/CDK6/CD36/BCL2/BCL6/RHOA/ARHGAP6/BST1/APOD/CDKN2A/CDH13/ABL1" 13 +"GO:0030048" "GO:0030048" "actin filament-based movement" "15/743" "130/17381" 0.000442900435565524 0.00229660295997153 0.00137807856230176 "CACNA1C/ACTA1/ACTN2/ATP1A1/CAMK2D/CAV3/CACNA2D1/ACTN3/ATP1A2/CAV1/CACNA1D/ACTC1/ACTN4/ANK2/CACNB2" 15 +"GO:0031396" "GO:0031396" "regulation of protein ubiquitination" "24/743" "265/17381" 0.000451679429959455 0.00233978083087105 0.00140398748051251 "BIRC2/ADRB2/CDK1/CCNB1/BUB1B/TSPO/ARRB1/ADGRB1/CAV3/CDC20/CDK9/CDK2/ARRB2/XIAP/CAV1/BMI1/BIRC3/BRCA1/CDK5/AVPR2/PTTG1IP/ABL1/CDC27/ANGPT1" 24 +"GO:0032103" "GO:0032103" "positive regulation of response to external stimulus" "25/743" "281/17381" 0.000452520443083646 0.00234179329295787 0.00140519506010185 "AIF1/CD6/CD74/AGT/CD47/AZU1/AGER/C3AR1/BTK/CASR/BMPR2/AGTR1/ADORA2B/BRAF/C3/APOH/CALR/C5AR1/BMP6/CDH13/ARG1/CD28/ADAM8/ADAM10/C1QBP" 25 +"GO:0070509" "GO:0070509" "calcium ion import" "10/743" "66/17381" 0.00046264837568632 0.00238942649119432 0.00143377740127602 "ATP2A2/ATP2B4/CAV3/CASR/CACNA2D1/CALCR/CACNA1D/ATP2A1/CDK5/CACNB2" 10 +"GO:1905710" "GO:1905710" "positive regulation of membrane permeability" "10/743" "66/17381" 0.00046264837568632 0.00238942649119432 0.00143377740127602 "BNIP3L/BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BNIP3/BAK1" 10 +"GO:0050871" "GO:0050871" "positive regulation of B cell activation" "14/743" "117/17381" 0.000469322878942586 0.00242148145416539 0.00145301200911017 "CD74/BTK/CD81/BAD/CD27/PRDM1/ADA/CDKN1A/BCL2/CD40/BCL6/CD38/BST1/CD28" 14 +"GO:2000027" "GO:2000027" "regulation of organ morphogenesis" "23/743" "250/17381" 0.000472545539238993 0.00243568044378664 0.00146153212492664 "BMP2/AP2B1/AMELX/AGT/BMPR1A/RUNX2/AR/CD34/CAV3/BMPR2/CDC42/BAX/BMP7/ARRB2/BCL2/AP2A1/RHOA/AGTR2/ACVR1/CEACAM1/AP2A2/BMP4/ABL1" 23 +"GO:0045931" "GO:0045931" "positive regulation of mitotic cell cycle" "16/743" "145/17381" 0.00047939100795964 0.00246850593650859 0.00148122908979412 "ANXA1/APP/BRCA2/AIF1/CDK1/CDK4/CCNB1/CCND2/CDC6/CDC25B/BTC/ASNS/CD28/APEX1/CCND1/ABL1" 16 +"GO:0071901" "GO:0071901" "negative regulation of protein serine/threonine kinase activity" "15/743" "131/17381" 0.00048087270812164 0.0024736742192142 0.00148433032223379 "CDKN1B/CDKN2D/APOE/APC/CAV3/BMP7/CDKN2B/CDKN1A/CAV1/CDKN1C/CASP3/CDKN2A/BMP4/CDKN2C/ABL1" 15 +"GO:0050731" "GO:0050731" "positive regulation of peptidyl-tyrosine phosphorylation" "18/743" "174/17381" 0.000481952911793507 0.00247676893597954 0.00148618730966482 "CD4/CD74/AGT/CD80/CD81/ADRA2B/CD3E/ADRA2C/AREG/CD36/ADRA2A/ARRB2/CD40/CCK/CD44/ABL1/ANGPT1/ADORA1" 18 +"GO:0043502" "GO:0043502" "regulation of muscle adaptation" "12/743" "91/17381" 0.000484703237641201 0.00248843180039009 0.00149318562138841 "CASQ1/AIF1/CAMK2B/AGT/ATP2A2/ATP2B4/CAMK2D/CAV3/CDK9/ACTN3/CAMK2G/PARP1" 12 +"GO:2000378" "GO:2000378" "negative regulation of reactive oxygen species metabolic process" "9/743" "55/17381" 0.000493972008375144 0.00253350361084378 0.00152023099964183 "ACP5/TSPO/CD34/ATP2B4/BCR/CAV1/BCL2/BRCA1/BNIP3" 9 +"GO:0032369" "GO:0032369" "negative regulation of lipid transport" "7/743" "34/17381" 0.000496544142176225 0.00254165770105041 0.0015251238684157 "APOC2/APOC3/AKT2/AKT1/APOA2/AGTR2/APOC1" 7 +"GO:2000772" "GO:2000772" "regulation of cellular senescence" "7/743" "34/17381" 0.000496544142176225 0.00254165770105041 0.0015251238684157 "CDK6/ARG2/BMPR1A/BCL6/ARNTL/CDKN2A/ABL1" 7 +"GO:1990778" "GO:1990778" "protein localization to cell periphery" "23/743" "251/17381" 0.000499798030522143 0.00255578538335187 0.00153360119621419 "BBS2/ANXA2/AKT2/ATP1B3/AKT1/AR/ACTN2/CDH2/BSG/CAV3/CALCR/ANK1/BBS1/RHOG/CAV1/ANK3/ATP1B1/ARF6/CDH1/ANK2/BCL2L1/CACNB2/CACNB3" 23 +"GO:1901568" "GO:1901568" "fatty acid derivative metabolic process" "17/743" "160/17381" 0.000503362964527939 0.0025714741771294 0.0015430152702836 "ANXA1/AVPR1A/ACOX1/CD74/ACAT1/ACACA/ACLY/ALOX12/ALOX15/CBR1/BDH1/ALOX12B/AVP/ALOX5/DAGLA/ALOX5AP/ALOX15B" 17 +"GO:0046718" "GO:0046718" "viral entry into host cell" "14/743" "118/17381" 0.000512030673358142 0.00261317429450531 0.0015680374612338 "SCARB2/AXL/CDK1/CD4/SCARB1/CD74/CD80/CD81/CAV1/ANPEP/CAV2/GRK2/APCS/CD86" 14 +"GO:0001938" "GO:0001938" "positive regulation of endothelial cell proliferation" "11/743" "79/17381" 0.000515563762793544 0.00262602605556751 0.00157574917140588 "BMP2/ACVRL1/AKT1/ARNT/BMPR2/ANG/BMP6/CAV2/CDH13/ARG1/BMP4" 11 +"GO:0046634" "GO:0046634" "regulation of alpha-beta T cell activation" "11/743" "79/17381" 0.000515563762793544 0.00262602605556751 0.00157574917140588 "ANXA1/ARG2/AGER/CD80/CD3E/PRDM1/ADA/BCL6/ADORA2A/CD28/CD86" 11 +"GO:1901990" "GO:1901990" "regulation of mitotic cell cycle phase transition" "33/743" "417/17381" 0.000520355547845186 0.00264782690275205 0.00158883078832821 "ANXA1/APP/CDKN1B/CDC25C/BID/AIF1/CDK1/CDK4/CDK6/CCNB1/BUB1B/AKT1/CCND2/BUB1/APC/CASP2/CDC20/CDK3/CDC6/BAX/CDK2/CDKN2B/CDKN1A/ZFP36L2/BCL2/BLM/ATM/ZFP36L1/CDKN1C/BRCA1/APEX1/CCND1/CDC27" 33 +"GO:0002718" "GO:0002718" "regulation of cytokine production involved in immune response" "10/743" "67/17381" 0.00052335051470458 0.00265199767161156 0.00159133346173488 "CD74/BTK/CD36/APOA1/BCL6/APOA2/BST2/ARG1/B2M/ANGPT1" 10 +"GO:0072401" "GO:0072401" "signal transduction involved in DNA integrity checkpoint" "10/743" "67/17381" 0.00052335051470458 0.00265199767161156 0.00159133346173488 "CDKN1B/CDC25C/CDK1/CCNB1/CDC5L/CASP2/BAX/CDK2/CDKN1A/ATM" 10 +"GO:0072422" "GO:0072422" "signal transduction involved in DNA damage checkpoint" "10/743" "67/17381" 0.00052335051470458 0.00265199767161156 0.00159133346173488 "CDKN1B/CDC25C/CDK1/CCNB1/CDC5L/CASP2/BAX/CDK2/CDKN1A/ATM" 10 +"GO:1904035" "GO:1904035" "regulation of epithelial cell apoptotic process" "10/743" "67/17381" 0.00052335051470458 0.00265199767161156 0.00159133346173488 "BOK/CAST/KRIT1/FASLG/BRAF/CD40/ZFP36L1/CD40LG/ABL1/ANGPT1" 10 +"GO:0010506" "GO:0010506" "regulation of autophagy" "26/743" "300/17381" 0.000523737511185896 0.00265199767161156 0.00159133346173488 "ATP6V1C1/BNIP3L/CASP1/ADRB2/ABL2/AKT1/ATP6V1B2/TSPO/ATP6V0A1/BAD/BOK/ATP6V1B1/ATP6V1A/ACTL6A/CAPNS1/CAPN1/ATP6V1G2/ATP6V0C/BCL2/ATP6V0B/ATP6V1E1/ATM/CASP3/CDK5/BNIP3/ABL1" 26 +"GO:0002719" "GO:0002719" "negative regulation of cytokine production involved in immune response" "6/743" "25/17381" 0.000527040519979573 0.00265314658647304 0.00159202286907612 "APOA1/BCL6/APOA2/BST2/ARG1/ANGPT1" 6 +"GO:0003309" "GO:0003309" "type B pancreatic cell differentiation" "6/743" "25/17381" 0.000527040519979573 0.00265314658647304 0.00159202286907612 "CDK6/BAD/ARNTL/BMP6/BMP5/BMP4" 6 +"GO:0006700" "GO:0006700" "C21-steroid hormone biosynthetic process" "6/743" "25/17381" 0.000527040519979573 0.00265314658647304 0.00159202286907612 "BMP2/ADM/TSPO/AKR1B1/BMP6/BMP5" 6 +"GO:0010460" "GO:0010460" "positive regulation of heart rate" "6/743" "25/17381" 0.000527040519979573 0.00265314658647304 0.00159202286907612 "ADM/AVPR1A/ATP2A2/ADRA1A/ADA/ADRB1" 6 +"GO:0045736" "GO:0045736" "negative regulation of cyclin-dependent protein serine/threonine kinase activity" "6/743" "25/17381" 0.000527040519979573 0.00265314658647304 0.00159202286907612 "CDKN1B/APC/CDKN1A/CASP3/CDKN2A/CDKN2C" 6 +"GO:0060037" "GO:0060037" "pharyngeal system development" "6/743" "25/17381" 0.000527040519979573 0.00265314658647304 0.00159202286907612 "BMPR1A/BMPR2/BMP7/ACVR1/BMP5/BMP4" 6 +"GO:0009791" "GO:0009791" "post-embryonic development" "12/743" "92/17381" 0.000536173380524044 0.00269388081962323 0.00161646548037397 "ASL/ATRX/ACVR2B/ACO1/PRDM1/BAX/BCL2/ATM/APOB/BMP4/ABL1/BAK1" 12 +"GO:0022617" "GO:0022617" "extracellular matrix disassembly" "12/743" "92/17381" 0.000536173380524044 0.00269388081962323 0.00161646548037397 "DDR1/ACAN/BSG/A2M/CAPNS1/BMP1/CAPN1/CAPN2/CDH1/CD44/ADAM8/ADAM10" 12 +"GO:0007093" "GO:0007093" "mitotic cell cycle checkpoint" "17/743" "161/17381" 0.000540952139705999 0.00271525443547871 0.00162929073677339 "CDKN1B/CDC25C/CDK1/CCNB1/BUB1B/BUB1/APC/CASP2/BAX/CDK2/CDKN2B/CDKN1A/BLM/ATM/BRCA1/BCL2L1/CCND1" 17 +"GO:0007160" "GO:0007160" "cell-matrix adhesion" "20/743" "206/17381" 0.000549049128539972 0.00275322600794026 0.00165207561117189 "ACVRL1/DDR1/CDK6/ACTN1/CD34/ACTN2/CD36/ACTN3/BCL2/BCL6/RHOA/CD63/ARHGAP6/BST1/APOD/CDK5/CDKN2A/CDH13/CD44/ABL1" 20 +"GO:0035821" "GO:0035821" "modification of morphology or physiology of other organism" "16/743" "147/17381" 0.000558302054965023 0.00279292141617392 0.00167589487469373 "SLC25A6/ANXA2/CD4/ALB/AZU1/APOE/BAD/CCNT1/CAMP/CASP8/C9/AQP1/CAV2/ARG1/BCL2L1/APCS" 16 +"GO:0000098" "GO:0000098" "sulfur amino acid catabolic process" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "CDO1/BLMH/CBS/AGXT" 4 +"GO:0001765" "GO:0001765" "membrane raft assembly" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "ANXA2/CAV3/CAV1/CAV2" 4 +"GO:0009071" "GO:0009071" "serine family amino acid catabolic process" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "CDO1/AMT/CBS/AGXT" 4 +"GO:0032464" "GO:0032464" "positive regulation of protein homooligomerization" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "BID/FAS/RHOC/BIK" 4 +"GO:0042759" "GO:0042759" "long-chain fatty acid biosynthetic process" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "ALOX12/ALOX15/ALOX12B/ALOX15B" 4 +"GO:0051006" "GO:0051006" "positive regulation of lipoprotein lipase activity" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "APOC2/APOA4/APOA1/APOH" 4 +"GO:0051901" "GO:0051901" "positive regulation of mitochondrial depolarization" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "TSPO/ALOX12/CCK/PARP1" 4 +"GO:0070471" "GO:0070471" "uterine smooth muscle contraction" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "AGT/ADRA2B/ADRA2C/ABAT" 4 +"GO:0071281" "GO:0071281" "cellular response to iron ion" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "CCNB1/ATP7A/BMP6/B2M" 4 +"GO:1904627" "GO:1904627" "response to phorbol 13-acetate 12-myristate" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "CDK4/CDK6/ZFP36L2/ZFP36L1" 4 +"GO:1990001" "GO:1990001" "inhibition of cysteine-type endopeptidase activity involved in apoptotic process" "4/743" "10/17381" 0.000565777307728917 0.00279292141617392 0.00167589487469373 "BIRC2/XIAP/BIRC3/BIRC5" 4 +"GO:0006577" "GO:0006577" "amino-acid betaine metabolic process" "5/743" "17/17381" 0.000567275265630974 0.00279292141617392 0.00167589487469373 "ALDH7A1/ALDH9A1/ACADM/ACADL/BHMT" 5 +"GO:0032717" "GO:0032717" "negative regulation of interleukin-8 production" "5/743" "17/17381" 0.000567275265630974 0.00279292141617392 0.00167589487469373 "ANXA1/BPI/ANXA4/ARRB1/BCL3" 5 +"GO:0032891" "GO:0032891" "negative regulation of organic acid transport" "5/743" "17/17381" 0.000567275265630974 0.00279292141617392 0.00167589487469373 "AKT2/AKT1/ABAT/AGTR2/ADORA1" 5 +"GO:0045019" "GO:0045019" "negative regulation of nitric oxide biosynthetic process" "5/743" "17/17381" 0.000567275265630974 0.00279292141617392 0.00167589487469373 "ACP5/TSPO/CD34/ATP2B4/CAV1" 5 +"GO:0070242" "GO:0070242" "thymocyte apoptotic process" "5/743" "17/17381" 0.000567275265630974 0.00279292141617392 0.00167589487469373 "BAX/ADA/ADAM8/BMP4/BAK1" 5 +"GO:0070816" "GO:0070816" "phosphorylation of RNA polymerase II C-terminal domain" "5/743" "17/17381" 0.000567275265630974 0.00279292141617392 0.00167589487469373 "CCNC/CCNH/CCNT1/CDK9/CCNT2" 5 +"GO:1904406" "GO:1904406" "negative regulation of nitric oxide metabolic process" "5/743" "17/17381" 0.000567275265630974 0.00279292141617392 0.00167589487469373 "ACP5/TSPO/CD34/ATP2B4/CAV1" 5 +"GO:1903115" "GO:1903115" "regulation of actin filament-based movement" "8/743" "45/17381" 0.000568298792508432 0.00279292141617392 0.00167589487469373 "CACNA1C/ATP2A2/ATP1A1/CAMK2D/CAV3/ATP1A2/CAV1/ANK2" 8 +"GO:2000272" "GO:2000272" "negative regulation of receptor activity" "8/743" "45/17381" 0.000568298792508432 0.00279292141617392 0.00167589487469373 "CALM1/CALM3/AGER/CALM2/CBLB/CAV1/CASQ2/CBL" 8 +"GO:0051651" "GO:0051651" "maintenance of location in cell" "11/743" "80/17381" 0.000575116024642717 0.00282374328987292 0.00169438956625988 "CD4/AKT1/ALB/TSPO/APOE/BBS4/ARL2/CAV1/ANK3/ATP2A1/BCL3" 11 +"GO:0016241" "GO:0016241" "regulation of macroautophagy" "17/743" "162/17381" 0.000580929444651048 0.00284688435233823 0.00170827538050298 "ATP6V1C1/BNIP3L/ADRB2/AKT1/ATP6V1B2/ATP6V0A1/ATP6V1B1/ATP6V1A/CAPNS1/CAPN1/ATP6V1G2/ATP6V0C/ATP6V0B/ATP6V1E1/CASP3/CDK5/BNIP3" 17 +"GO:0046661" "GO:0046661" "male sex differentiation" "17/743" "162/17381" 0.000580929444651048 0.00284688435233823 0.00170827538050298 "ATRX/BCL2L2/BMPR1A/AR/NR0B1/BOK/AMH/BAX/AMHR2/BCL2/BIK/BMP6/BMP5/ACVR2A/BCL2L1/CCND1/CBL" 17 +"GO:0072395" "GO:0072395" "signal transduction involved in cell cycle checkpoint" "10/743" "68/17381" 0.000590503312314189 0.00289106399359123 0.00173478541186761 "CDKN1B/CDC25C/CDK1/CCNB1/CDC5L/CASP2/BAX/CDK2/CDKN1A/ATM" 10 +"GO:0014706" "GO:0014706" "striated muscle tissue development" "30/743" "369/17381" 0.000593031911489553 0.00290069956706847 0.00174056724593989 "BMP2/CASQ1/KLF5/CDK1/AGT/CCNB1/BMPR1A/ACTA1/ACTN2/BCL9/CAV3/FOXL2/CAPN3/CDC42/ACTN3/BMP7/ARRB2/CAV1/BCL2/ATF3/CCNT2/ACTC1/AGTR2/ACVR1/CALR/ARNTL/CAV2/BMP5/CDK5/BMP4" 30 +"GO:0050892" "GO:0050892" "intestinal absorption" "7/743" "35/17381" 0.000598057160040801 0.00291976019170863 0.00175200458999043 "SCARB1/APOA4/ACO1/CD36/APOA1/ADRA2A/APOA2" 7 +"GO:0060306" "GO:0060306" "regulation of membrane repolarization" "7/743" "35/17381" 0.000598057160040801 0.00291976019170863 0.00175200458999043 "CAV3/CACNA2D1/CAV1/CACNA1D/CASQ2/ANK2/CACNB3" 7 +"GO:0050806" "GO:0050806" "positive regulation of synaptic transmission" "15/743" "134/17381" 0.000611930109274569 0.00298467324740423 0.00179095572435138 "APP/ADRB2/CALB1/AGER/APOE/ADRA1A/ARRB2/ABAT/BRAF/ADCYAP1/ADORA2A/CA2/CA7/ABL1/ADORA1" 15 +"GO:0006469" "GO:0006469" "negative regulation of protein kinase activity" "23/743" "255/17381" 0.000623009386475567 0.00303585082392755 0.00182166487273558 "CDKN1B/CDKN2D/AKT1/APOE/APC/CAV3/ADAR/CBLB/BGN/ADARB1/BMP7/CDKN2B/CDKN1A/CAV1/CEACAM1/ADORA2A/CDKN1C/CASP3/CDKN2A/BMP4/CDKN2C/ABL1/CBL" 23 +"GO:1903035" "GO:1903035" "negative regulation of response to wounding" "11/743" "81/17381" 0.000640296166274761 0.00311715207946556 0.00187044976037089 "ANXA2/AGER/APOE/CD34/CD9/ALOX12/ABAT/APOH/CEACAM1/APCS/SERPING1" 11 +"GO:0045577" "GO:0045577" "regulation of B cell differentiation" "6/743" "26/17381" 0.000660615510222625 0.00321305006146813 0.00192799342615428 "BTK/BAD/CD27/PRDM1/ZFP36L2/ZFP36L1" 6 +"GO:0046164" "GO:0046164" "alcohol catabolic process" "8/743" "46/17381" 0.000662547018951387 0.0032133840891035 0.0019281938597214 "SCARB1/ALDH1B1/APOE/ADH7/ADH4/ALDH3B1/ALDH3B2/ALDH2" 8 +"GO:0090329" "GO:0090329" "regulation of DNA-dependent DNA replication" "8/743" "46/17381" 0.000662547018951387 0.0032133840891035 0.0019281938597214 "BRCA2/ATRX/CDK2/BCL6/BLM/BMP6/BMP5/BMP4" 8 +"GO:1901028" "GO:1901028" "regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway" "8/743" "46/17381" 0.000662547018951387 0.0032133840891035 0.0019281938597214 "BID/BAD/SLC25A5/BOK/BAX/CASP8/BCL2/BAK1" 8 +"GO:0021543" "GO:0021543" "pallium development" "17/743" "164/17381" 0.000668543705344522 0.00323943228011039 0.00194382409892208 "BCL2A1/BBS2/CDK6/ALK/BAD/ATP1A3/CDH2/ATP2B4/ASCL1/BBS4/ATIC/BAX/ANXA3/ATOH1/CASP3/CDK5/BNIP3" 17 +"GO:0044089" "GO:0044089" "positive regulation of cellular component biogenesis" "37/743" "493/17381" 0.000670363140894894 0.00324520977935555 0.00194729089226521 "CDKN1B/ATR/BID/FAS/AGT/SEPT7/ASIC2/ADGRB3/ARF1/ADGRB1/APC/CAV3/ADGRB2/BBS4/CD36/ATP7A/CDC34/CDC42/BAX/ARL2/BDNF/APOA1/BMP7/ALOX15/RHOC/CAV1/BRAF/RHOA/CCK/BIK/ATM/AQP1/ARF6/PARP1/CBLN1/CDH17/ABL1" 37 +"GO:0071559" "GO:0071559" "response to transforming growth factor beta" "21/743" "225/17381" 0.000679329707603238 0.00328554321200631 0.001971493002882 "ACVRL1/ZFHX3/BMPR1A/CAV3/CDH5/AMHR2/CDKN2B/ZFP36L2/ARRB2/CAV1/RHOA/ACVR1/PARP1/CAV2/ZFP36L1/CDKN1C/RUNX3/ARG1/APAF1/LDLRAD4/CBL" 21 +"GO:0071695" "GO:0071695" "anatomical structure maturation" "16/743" "150/17381" 0.000697415074658931 0.00336986275570492 0.00202208901689896 "APP/BMP2/BRCA2/ACVRL1/CCNB1/ADGRB3/CDH3/ARCN1/RERE/CDH5/ANG/CDKN1A/CDC25B/BCL2/RHOA/CDKN1C" 16 +"GO:0006778" "GO:0006778" "porphyrin-containing compound metabolic process" "7/743" "36/17381" 0.000715374464508434 0.00343738426539568 0.0020626053563015 "BLVRB/ALAS2/ALAS1/TSPO/BLVRA/ALAD/AMBP" 7 +"GO:0008207" "GO:0008207" "C21-steroid hormone metabolic process" "7/743" "36/17381" 0.000715374464508434 0.00343738426539568 0.0020626053563015 "BMP2/ADM/TSPO/AFP/AKR1B1/BMP6/BMP5" 7 +"GO:0043267" "GO:0043267" "negative regulation of potassium ion transport" "7/743" "36/17381" 0.000715374464508434 0.00343738426539568 0.0020626053563015 "ACTN2/CAV3/CAV1/ANK3/CASQ2/ADCYAP1/ATF4" 7 +"GO:0045823" "GO:0045823" "positive regulation of heart contraction" "7/743" "36/17381" 0.000715374464508434 0.00343738426539568 0.0020626053563015 "ADM/AVPR1A/ATP2A2/ADRA1A/ATP1A1/ADA/ADRB1" 7 +"GO:0048536" "GO:0048536" "spleen development" "7/743" "36/17381" 0.000715374464508434 0.00343738426539568 0.0020626053563015 "FAS/CDKN2B/BCL2/BCL3/NKX3-2/CDH17/ABL1" 7 +"GO:0086091" "GO:0086091" "regulation of heart rate by cardiac conduction" "7/743" "36/17381" 0.000715374464508434 0.00343738426539568 0.0020626053563015 "CACNA1C/CAMK2D/CACNA2D1/CAV1/CACNA1D/ANK2/CACNB2" 7 +"GO:0002703" "GO:0002703" "regulation of leukocyte mediated immunity" "17/743" "165/17381" 0.000716439782180953 0.00343930971501524 0.00206376072398575 "C4BPA/AGER/BTK/ABR/BCR/AP1G1/ADORA2B/ARRB2/CD40/BCL6/C4BPB/C3/CEACAM1/BST2/ARG1/CD28/B2M" 17 +"GO:0007043" "GO:0007043" "cell-cell junction assembly" "12/743" "95/17381" 0.000718936419325466 0.00344809635774725 0.00206903315644127 "AGT/RUNX1/APC/CD9/CDH5/ARL2/RHOC/CAV1/RHOA/CBFB/ACTN4/ANK2" 12 +"GO:0002902" "GO:0002902" "regulation of B cell apoptotic process" "5/743" "18/17381" 0.000758005996867418 0.00361537422469022 0.00216940838298218 "CD74/BTK/BAX/ADA/BCL6" 5 +"GO:0010544" "GO:0010544" "negative regulation of platelet activation" "5/743" "18/17381" 0.000758005996867418 0.00361537422469022 0.00216940838298218 "APOE/CD9/ALOX12/ABAT/CEACAM1" 5 +"GO:0032026" "GO:0032026" "response to magnesium ion" "5/743" "18/17381" 0.000758005996867418 0.00361537422469022 0.00216940838298218 "ENTPD6/ANK3/CD14/BMP6/CCND1" 5 +"GO:0045076" "GO:0045076" "regulation of interleukin-2 biosynthetic process" "5/743" "18/17381" 0.000758005996867418 0.00361537422469022 0.00216940838298218 "CD4/CD80/CD3E/CD28/CD86" 5 +"GO:0045655" "GO:0045655" "regulation of monocyte differentiation" "5/743" "18/17381" 0.000758005996867418 0.00361537422469022 0.00216940838298218 "CD4/CDK6/CD74/ZFP36L1/APCS" 5 +"GO:0051412" "GO:0051412" "response to corticosterone" "5/743" "18/17381" 0.000758005996867418 0.00361537422469022 0.00216940838298218 "AVPR1A/ATP2B1/CDKN1A/AANAT/CCND1" 5 +"GO:0006690" "GO:0006690" "icosanoid metabolic process" "13/743" "109/17381" 0.000762953871480648 0.00363562273012187 0.00218155851591345 "ANXA1/AVPR1A/ACOX1/CD74/ALOX12/ALOX15/CBR1/ALOX12B/AVP/ALOX5/DAGLA/ALOX5AP/ALOX15B" 13 +"GO:0000281" "GO:0000281" "mitotic cytokinesis" "8/743" "47/17381" 0.000768998241410533 0.00364763143840468 0.00218876435154718 "ARF1/APC/BBS4/RHOC/ANK3/RHOA/RHOB/ARL3" 8 +"GO:0002067" "GO:0002067" "glandular epithelial cell differentiation" "8/743" "47/17381" 0.000768998241410533 0.00364763143840468 0.00218876435154718 "BMP2/CDK6/BAD/ASCL1/ARNTL/BMP6/BMP5/BMP4" 8 +"GO:0032720" "GO:0032720" "negative regulation of tumor necrosis factor production" "8/743" "47/17381" 0.000768998241410533 0.00364763143840468 0.00218876435154718 "AXL/BPI/ARG2/ACP5/TSPO/CD34/ARRB2/BCL3" 8 +"GO:0045839" "GO:0045839" "negative regulation of mitotic nuclear division" "8/743" "47/17381" 0.000768998241410533 0.00364763143840468 0.00218876435154718 "ATRX/CCNB1/BUB1B/BUB1/APC/BMP7/ATM/BMP4" 8 +"GO:1905953" "GO:1905953" "negative regulation of lipid localization" "8/743" "47/17381" 0.000768998241410533 0.00364763143840468 0.00218876435154718 "APOC2/APOC3/AKT2/AKT1/ABCA1/APOA2/AGTR2/APOC1" 8 +"GO:0032612" "GO:0032612" "interleukin-1 production" "11/743" "83/17381" 0.00078918327854399 0.00373652650179794 0.00224210591005419 "ANXA1/CASP1/ARG2/AZU1/ACP5/CASP5/ABCA1/CD36/APOA1/ARRB2/CEACAM1" 11 +"GO:0070542" "GO:0070542" "response to fatty acid" "11/743" "83/17381" 0.00078918327854399 0.00373652650179794 0.00224210591005419 "CDK4/CCNB1/AKT1/ADCY6/BAD/ACACA/CD36/ALAD/CAT/APOB/AANAT" 11 +"GO:0006606" "GO:0006606" "protein import into nucleus" "24/743" "276/17381" 0.000806228487116894 0.00381374078686465 0.00228843840757706 "APP/CDK1/AGT/AKT1/BMPR1A/AGER/RERE/CD27/CD36/CBLB/BMP7/CDKN1A/BCL6/RHOA/BCL3/AGTR2/PARP1/ARNTL/BMP6/CDH1/APOD/BMP4/PTTG1IP/ANGPT1" 24 +"GO:0050663" "GO:0050663" "cytokine secretion" "19/743" "197/17381" 0.000810079033351674 0.00382845570556613 0.00229726810707757 "ANXA1/CASP1/ANXA4/ARG2/AGT/CASP5/CD34/C5/ABCA1/CD36/APOA1/APOA2/CD2/AGTR2/CD14/CD58/ABL1/ALOX15B/ANGPT1" 19 +"GO:0050808" "GO:0050808" "synapse organization" "23/743" "260/17381" 0.000813566001874346 0.00383824329284629 0.00230314115716177 "APP/CACNB4/CAMK2B/ASIC2/ADGRB3/APOE/ADGRB1/CDH2/ADGRB2/CDC20/CDC42/BDNF/ACTB/ACHE/ANK3/CACNB1/CDH1/CDH9/CDK5/CBLN1/CACNB2/CACNB3/ABL1" 23 +"GO:0051056" "GO:0051056" "regulation of small GTPase mediated signal transduction" "26/743" "309/17381" 0.000813633409130894 0.00383824329284629 0.00230314115716177 "ARHGAP5/APOC3/ARHGDIG/RHOH/ARHGDIA/APOE/ARRB1/ADRA1A/ABR/BCR/ABCA1/A2M/CDC42/ADCYAP1R1/APOA1/RHOG/RHOC/ARHGAP4/BCL6/RHOA/ARHGAP6/ARF6/RHOB/ARHGAP1/ARHGDIB/ABL1" 26 +"GO:0035883" "GO:0035883" "enteroendocrine cell differentiation" "6/743" "27/17381" 0.000818971079179932 0.00385990467646279 0.00231613908885131 "CDK6/BAD/ARNTL/BMP6/BMP5/BMP4" 6 +"GO:0001895" "GO:0001895" "retina homeostasis" "10/743" "71/17381" 0.000835957254935755 0.00392566133783351 0.00235559642951617 "BBS2/ALB/CDH3/BBS4/ACTB/BBS1/ACTG1/AZGP1/ABCA4/B2M" 10 +"GO:0007422" "GO:0007422" "peripheral nervous system development" "10/743" "71/17381" 0.000835957254935755 0.00392566133783351 0.00235559642951617 "CDK1/AKT2/AKT1/ASIC2/RUNX1/ADGRB1/ADGRB2/ALDH3A2/CDK5/RUNX3" 10 +"GO:0031571" "GO:0031571" "mitotic G1 DNA damage checkpoint" "10/743" "71/17381" 0.000835957254935755 0.00392566133783351 0.00235559642951617 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM/CCND1" 10 +"GO:0044819" "GO:0044819" "mitotic G1/S transition checkpoint" "10/743" "71/17381" 0.000835957254935755 0.00392566133783351 0.00235559642951617 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM/CCND1" 10 +"GO:0032623" "GO:0032623" "interleukin-2 production" "9/743" "59/17381" 0.000838551948804985 0.00393427591574415 0.00236076561432906 "ANXA1/CD4/RUNX1/CD80/CD34/CD3E/CD28/CD86/ABL1" 9 +"GO:0042092" "GO:0042092" "type 2 immune response" "7/743" "37/17381" 0.00085018148277788 0.00398161916142582 0.00238917396922576 "ANXA1/ARG2/CD74/BCL6/BCL3/ARG1/CD86" 7 +"GO:1901030" "GO:1901030" "positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway" "7/743" "37/17381" 0.00085018148277788 0.00398161916142582 0.00238917396922576 "BID/BAD/BOK/BAX/CASP8/BCL2/BAK1" 7 +"GO:0040015" "GO:0040015" "negative regulation of multicellular organism growth" "4/743" "11/17381" 0.00085909327096075 0.00399802848671032 0.00239902039883966 "BBS2/ADRB2/ADRB3/ADRB1" 4 +"GO:0043116" "GO:0043116" "negative regulation of vascular permeability" "4/743" "11/17381" 0.00085909327096075 0.00399802848671032 0.00239902039883966 "ADM/CEACAM1/ADORA2A/ANGPT1" 4 +"GO:0060315" "GO:0060315" "negative regulation of ryanodine-sensitive calcium-release channel activity" "4/743" "11/17381" 0.00085909327096075 0.00399802848671032 0.00239902039883966 "CALM1/CALM3/CALM2/CASQ2" 4 +"GO:0061365" "GO:0061365" "positive regulation of triglyceride lipase activity" "4/743" "11/17381" 0.00085909327096075 0.00399802848671032 0.00239902039883966 "APOC2/APOA4/APOA1/APOH" 4 +"GO:0090331" "GO:0090331" "negative regulation of platelet aggregation" "4/743" "11/17381" 0.00085909327096075 0.00399802848671032 0.00239902039883966 "CD9/ALOX12/ABAT/CEACAM1" 4 +"GO:0097202" "GO:0097202" "activation of cysteine-type endopeptidase activity" "4/743" "11/17381" 0.00085909327096075 0.00399802848671032 0.00239902039883966 "ASPH/BAD/CASP8/BAK1" 4 +"GO:1901407" "GO:1901407" "regulation of phosphorylation of RNA polymerase II C-terminal domain" "4/743" "11/17381" 0.00085909327096075 0.00399802848671032 0.00239902039883966 "CCNC/CCNH/CCNT1/CCNT2" 4 +"GO:0009409" "GO:0009409" "response to cold" "8/743" "48/17381" 0.000888774750807049 0.00412503079410446 0.0024752282415679 "ADM/ADRB2/ATP2B1/ADRB3/CDH8/ADRB1/CASP8/ACADVL" 8 +"GO:0048260" "GO:0048260" "positive regulation of receptor-mediated endocytosis" "8/743" "48/17381" 0.000888774750807049 0.00412503079410446 0.0024752282415679 "ANXA2/ARRB1/ARRB2/BICD1/CD63/CBL/B2M/ANGPT1" 8 +"GO:0050433" "GO:0050433" "regulation of catecholamine secretion" "8/743" "48/17381" 0.000888774750807049 0.00412503079410446 0.0024752282415679 "AGT/ADRA2B/ADRA2C/ADRA2A/ABAT/AGTR2/ADORA2A/GRK2" 8 +"GO:0002761" "GO:0002761" "regulation of myeloid leukocyte differentiation" "13/743" "111/17381" 0.000906501656242643 0.00420353590596387 0.0025223353008072 "CD4/CDK6/CD74/RUNX1/BGLAP/ATP6AP1/CASP8/CEACAM1/ZFP36L1/CAMK4/C1QC/CA2/APCS" 13 +"GO:0050769" "GO:0050769" "positive regulation of neurogenesis" "32/743" "414/17381" 0.000932775711895088 0.00431873911620363 0.00259146308523788 "APP/SCARB2/BMP2/ATF1/ABL2/CAMK2B/AGT/BIN1/AGER/ARHGDIA/TSPO/APOE/ARF1/ADRA2B/ASPA/ASCL1/ADRA2C/BMPR2/BDNF/BMP7/BCL2/BRAF/BCL6/ATOH1/RHOA/APBB1/ARSB/BMP6/ADCYAP1/BMP5/BMP4/CDH4" 32 +"GO:0006694" "GO:0006694" "steroid biosynthetic process" "18/743" "184/17381" 0.000933014556891915 0.00431873911620363 0.00259146308523788 "BMP2/ADM/SCARB1/BAAT/ACAT2/TSPO/APOE/APOA4/NR0B1/ACACA/ATP1A1/ACLY/APOA1/ACACB/AKR1B1/BMP6/BMP5/APOB" 18 +"GO:0044783" "GO:0044783" "G1 DNA damage checkpoint" "10/743" "72/17381" 0.000934334770289601 0.00432098519772001 0.00259281084836492 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM/CCND1" 10 +"GO:0042108" "GO:0042108" "positive regulation of cytokine biosynthetic process" "9/743" "60/17381" 0.000949793809347044 0.00438073347894024 0.00262866285540274 "CD4/AZU1/CD80/CD3E/TNFRSF8/BCL3/APOA2/CD28/CD86" 9 +"GO:0071242" "GO:0071242" "cellular response to ammonium ion" "9/743" "60/17381" 0.000949793809347044 0.00438073347894024 0.00262866285540274 "AIF1/AOC1/CASP6/CASP7/GRK2/CASP3/CCNA2/ATF4/ABL1" 9 +"GO:0090398" "GO:0090398" "cellular senescence" "9/743" "60/17381" 0.000949793809347044 0.00438073347894024 0.00262866285540274 "CDK6/ARG2/BMPR1A/CDKN1A/BCL6/CALR/ARNTL/CDKN2A/ABL1" 9 +"GO:0043010" "GO:0043010" "camera-type eye development" "25/743" "296/17381" 0.000963551995636468 0.00444023292735416 0.00266436555010318 "CDKN1B/ACVR2B/ACVRL1/CACNA1C/BFSP1/CDK4/CALB1/ATP2B1/ATP2B4/CASP2/SHROOM2/BMPR2/FOXL2/BAX/ACTL6A/ACHE/BMP7/BMPR1B/ALDH1A3/AQP1/CDKN1C/AQP5/JAG1/BMP4/BAK1" 25 +"GO:0007597" "GO:0007597" "blood coagulation, intrinsic pathway" "5/743" "19/17381" 0.000992808126694001 0.0045576990625916 0.0027348512046062 "SERPINC1/A2M/APOH/C1QBP/SERPING1" 5 +"GO:0010288" "GO:0010288" "response to lead ion" "5/743" "19/17381" 0.000992808126694001 0.0045576990625916 0.0027348512046062 "APP/CDK4/ATP7A/ALAD/CAT" 5 +"GO:0010523" "GO:0010523" "negative regulation of calcium ion transport into cytosol" "5/743" "19/17381" 0.000992808126694001 0.0045576990625916 0.0027348512046062 "CALM1/CALM3/CALM2/BCL2/CASQ2" 5 +"GO:0090208" "GO:0090208" "positive regulation of triglyceride metabolic process" "5/743" "19/17381" 0.000992808126694001 0.0045576990625916 0.0027348512046062 "APOC2/SCARB1/APOA4/AADAC/APOA1" 5 +"GO:0043123" "GO:0043123" "positive regulation of I-kappaB kinase/NF-kappaB signaling" "18/743" "185/17381" 0.000993446288425763 0.0045576990625916 0.0027348512046062 "APP/BIRC2/CASP1/CD4/CD74/AKT1/AGER/CD27/CD36/CASP10/FASLG/RHOC/CASP8/CD40/RHOA/BST2/BIRC3/ABL1" 18 +"GO:0042129" "GO:0042129" "regulation of T cell proliferation" "16/743" "155/17381" 0.000994944664432988 0.00456053023776857 0.00273655005368264 "ANXA1/AIF1/CD6/CD4/ARG2/AGER/CD80/CD3E/CASP3/CD59/ARG1/CD28/CD1D/CD40LG/BMP4/CD86" 16 +"GO:0002686" "GO:0002686" "negative regulation of leukocyte migration" "7/743" "38/17381" 0.00100425237742305 0.00459470041976797 0.00275705390049642 "ABR/BCR/C5/ADA/BMP5/APOD/ADORA1" 7 +"GO:0046320" "GO:0046320" "regulation of fatty acid oxidation" "6/743" "28/17381" 0.00100506297104876 0.00459470041976797 0.00275705390049642 "AKT2/AKT1/ABCD2/ACADVL/ACADL/ACACB" 6 +"GO:0051385" "GO:0051385" "response to mineralocorticoid" "6/743" "28/17381" 0.00100506297104876 0.00459470041976797 0.00275705390049642 "AVPR1A/ATP2B1/CDKN1A/PARP1/AANAT/CCND1" 6 +"GO:0000086" "GO:0000086" "G2/M transition of mitotic cell cycle" "22/743" "248/17381" 0.00100861599269065 0.00460687357649964 0.00276435841356195 "APP/CDC25C/CDK1/CCNH/CDK4/CDK6/CALM3/CCNB1/BACH1/CDK7/CALM2/CDK3/CDK2/CDKN2B/CDKN1A/CDC25B/BLM/ATM/BRCA1/CCNA2/CDC25A/CCND1" 22 +"GO:0045933" "GO:0045933" "positive regulation of muscle contraction" "8/743" "49/17381" 0.0010230546653958 0.00465638337152444 0.0027940668082374 "ADRA1D/ADRA1A/ATP1A1/ADRA2B/ADRA1B/ADA/ABAT/ATP2A1" 8 +"GO:0071320" "GO:0071320" "cellular response to cAMP" "8/743" "49/17381" 0.0010230546653958 0.00465638337152444 0.0027940668082374 "APP/AQP8/AQP9/HCN2/AQP1/ZFP36L1/APEX1/AANAT" 8 +"GO:0072577" "GO:0072577" "endothelial cell apoptotic process" "8/743" "49/17381" 0.0010230546653958 0.00465638337152444 0.0027940668082374 "BMPR2/KRIT1/FASLG/BRAF/CD40/CD40LG/ABL1/ANGPT1" 8 +"GO:1903556" "GO:1903556" "negative regulation of tumor necrosis factor superfamily cytokine production" "8/743" "49/17381" 0.0010230546653958 0.00465638337152444 0.0027940668082374 "AXL/BPI/ARG2/ACP5/TSPO/CD34/ARRB2/BCL3" 8 +"GO:0036294" "GO:0036294" "cellular response to decreased oxygen levels" "19/743" "201/17381" 0.0010314115484593 0.00468617626275405 0.00281194405799633 "BNIP3L/CCNB1/AKT1/BACH1/CA9/ARNT/BAD/CD34/CASR/ATP7A/BMP7/BCL2/AQP3/AQP1/ZFP36L1/CCNA2/ADAM8/BNIP3/CBL" 19 +"GO:0090276" "GO:0090276" "regulation of peptide hormone secretion" "19/743" "201/17381" 0.0010314115484593 0.00468617626275405 0.00281194405799633 "SLC25A6/CACNA1C/ARRB1/ADCY5/BAD/SLC25A5/BLK/ADRA2C/CASR/ARL2/ADRA2A/ABAT/CD38/CACNA1D/ARNTL/ADCYAP1/CACNA1E/CACNA1A/SLC25A4" 19 +"GO:0045666" "GO:0045666" "positive regulation of neuron differentiation" "27/743" "331/17381" 0.00103914892685259 0.00471718920742294 0.0028305534018607 "SCARB2/BMP2/ATF1/ABL2/CAMK2B/AGT/ARHGDIA/APOE/ARF1/ADRA2B/ASCL1/ADRA2C/BMPR2/BDNF/BMP7/BCL2/BRAF/BCL6/ATOH1/RHOA/APBB1/ARSB/BMP6/ADCYAP1/BMP5/BMP4/CDH4" 27 +"GO:1901215" "GO:1901215" "negative regulation of neuron death" "18/743" "186/17381" 0.00105718745617636 0.00479066995246293 0.00287464558551043 "AARS/AXL/AKT1/APOE/CD34/BOK/BAX/BDNF/BCL2/BRAF/C5AR1/ADORA2A/CDK5/ADAM8/BCL2L1/ATF4/CBL/ANGPT1" 18 +"GO:1903531" "GO:1903531" "negative regulation of secretion by cell" "18/743" "186/17381" 0.00105718745617636 0.00479066995246293 0.00287464558551043 "ANXA1/ANXA4/ARG2/CD34/ABR/ADRA2B/BCR/ADRA2C/APOA1/ADRA2A/ABAT/BRAF/APOA2/AGTR2/CEACAM1/ASIC1/ANGPT1/ADORA1" 18 +"GO:0045639" "GO:0045639" "positive regulation of myeloid cell differentiation" "11/743" "86/17381" 0.00106549287672875 0.0048240819221971 0.00289469446640864 "CD4/CD74/ACVR1B/RUNX1/ARNT/ATP6AP1/CASP8/ZFP36L1/ACVR2A/CA2/JAG1" 11 +"GO:0042306" "GO:0042306" "regulation of protein import into nucleus" "17/743" "172/17381" 0.00114135909529453 0.00516305359978075 0.00309809471026763 "APP/CDK1/BMPR1A/AGER/CD27/CD36/BMP7/CDKN1A/RHOA/BCL3/AGTR2/PARP1/BMP6/CDH1/APOD/BMP4/ANGPT1" 17 +"GO:0010823" "GO:0010823" "negative regulation of mitochondrion organization" "8/743" "50/17381" 0.00117307107239833 0.00529517212380589 0.00317737254314312 "AKT1/TSPO/SLC25A5/BOK/ARRB2/AVP/BCL2L1/BNIP3" 8 +"GO:2001238" "GO:2001238" "positive regulation of extrinsic apoptotic signaling pathway" "8/743" "50/17381" 0.00117307107239833 0.00529517212380589 0.00317737254314312 "BID/FAS/AGT/BAX/CAV1/ATF3/BMPR1B/AGTR2" 8 +"GO:0021782" "GO:0021782" "glial cell development" "11/743" "87/17381" 0.001173635251402 0.00529517212380589 0.00317737254314312 "APP/CDK6/AKT2/AKT1/AGER/CD9/ASPA/ASCL1/MYRF/ADORA2A/CDK5" 11 +"GO:0001659" "GO:0001659" "temperature homeostasis" "7/743" "39/17381" 0.00117944716638716 0.00531675878576095 0.00319032563803606 "ADRB2/ADRB3/ADRB1/ABAT/ACADVL/ACADL/ADORA1" 7 +"GO:0009132" "GO:0009132" "nucleoside diphosphate metabolic process" "15/743" "143/17381" 0.0012014438500778 0.00541120271901881 0.00324699680063168 "ALDOC/ALDOA/ENTPD5/ENTPD3/ARNT/AMPD3/BAD/ACTN3/BPGM/AK1/ALDOB/CBFA2T3/AK4/ENTPD2/AK2" 15 +"GO:0006977" "GO:0006977" "DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest" "9/743" "62/17381" 0.00120818542860804 0.00543683442873619 0.00326237712987984 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM" 9 +"GO:0003203" "GO:0003203" "endocardial cushion morphogenesis" "6/743" "29/17381" 0.00122198794958447 0.00547040453209309 0.00328252089899306 "BMP2/ACVRL1/BMPR1A/BMP7/ACVR1/BMP5" 6 +"GO:0006471" "GO:0006471" "protein ADP-ribosylation" "6/743" "29/17381" 0.00122198794958447 0.00547040453209309 0.00328252089899306 "ARF4/ART1/PARP4/ART3/PARP1/ART4" 6 +"GO:0010743" "GO:0010743" "regulation of macrophage derived foam cell differentiation" "6/743" "29/17381" 0.00122198794958447 0.00547040453209309 0.00328252089899306 "AGT/ABCA1/CD36/AGTR1/APOB/ALOX15B" 6 +"GO:0061900" "GO:0061900" "glial cell activation" "6/743" "29/17381" 0.00122198794958447 0.00547040453209309 0.00328252089899306 "APP/AIF1/AZU1/AGER/ATM/ADORA2A" 6 +"GO:0071709" "GO:0071709" "membrane assembly" "6/743" "29/17381" 0.00122198794958447 0.00547040453209309 0.00328252089899306 "ANXA2/CDH2/CAV3/CAV1/ANK3/CAV2" 6 +"GO:0090200" "GO:0090200" "positive regulation of release of cytochrome c from mitochondria" "6/743" "29/17381" 0.00122198794958447 0.00547040453209309 0.00328252089899306 "BID/BAD/BAX/BIK/BNIP3/BAK1" 6 +"GO:0051348" "GO:0051348" "negative regulation of transferase activity" "29/743" "369/17381" 0.00123223149754805 0.00551149351755504 0.00330717637971775 "CDKN1B/CDK1/CDKN2D/CCNB1/BUB1B/AKT1/APOE/APC/CAV3/ADAR/CDC20/CBLB/BGN/CDK2/ADARB1/BMP7/CDKN2B/CDKN1A/CAV1/CEACAM1/ADORA2A/CDKN1C/CASP3/CDKN2A/BMP4/CDKN2C/ABL1/CDC27/CBL" 29 +"GO:0042102" "GO:0042102" "positive regulation of T cell proliferation" "12/743" "101/17381" 0.00124261433214325 0.00553144899949536 0.00331915068365346 "ANXA1/AIF1/CD6/CD4/AGER/CD80/CD3E/CD59/CD28/CD1D/CD40LG/CD86" 12 +"GO:0045446" "GO:0045446" "endothelial cell differentiation" "12/743" "101/17381" 0.00124261433214325 0.00553144899949536 0.00331915068365346 "ACVR2B/ACVRL1/ADD1/CDH5/BMPR2/BTG1/ALOX12/ACVR1/CEACAM1/BMP6/JAG1/BMP4" 12 +"GO:0003084" "GO:0003084" "positive regulation of systemic arterial blood pressure" "4/743" "12/17381" 0.00124524407428253 0.00553144899949536 0.00331915068365346 "AVPR1A/ADRA1A/AVPR2/AVP" 4 +"GO:0008228" "GO:0008228" "opsonization" "4/743" "12/17381" 0.00124524407428253 0.00553144899949536 0.00331915068365346 "C4BPA/CD47/C4BPB/C4B" 4 +"GO:0014819" "GO:0014819" "regulation of skeletal muscle contraction" "4/743" "12/17381" 0.00124524407428253 0.00553144899949536 0.00331915068365346 "CASQ1/CAV3/ACTN3/ATP2A1" 4 +"GO:0045741" "GO:0045741" "positive regulation of epidermal growth factor-activated receptor activity" "4/743" "12/17381" 0.00124524407428253 0.00553144899949536 0.00331915068365346 "ADRA2B/ADRA2C/ADRA2A/ADORA1" 4 +"GO:0048711" "GO:0048711" "positive regulation of astrocyte differentiation" "4/743" "12/17381" 0.00124524407428253 0.00553144899949536 0.00331915068365346 "APP/BMP2/BIN1/AGER" 4 +"GO:0060391" "GO:0060391" "positive regulation of SMAD protein import into nucleus" "4/743" "12/17381" 0.00124524407428253 0.00553144899949536 0.00331915068365346 "BMPR1A/PARP1/BMP6/BMP4" 4 +"GO:0060537" "GO:0060537" "muscle tissue development" "30/743" "387/17381" 0.00127000888703281 0.00563661748747411 0.00338225712444417 "BMP2/CASQ1/KLF5/CDK1/AGT/CCNB1/BMPR1A/ACTA1/ACTN2/BCL9/CAV3/FOXL2/CAPN3/CDC42/ACTN3/BMP7/ARRB2/CAV1/BCL2/ATF3/CCNT2/ACTC1/AGTR2/ACVR1/CALR/ARNTL/CAV2/BMP5/CDK5/BMP4" 30 +"GO:0007620" "GO:0007620" "copulation" "5/743" "20/17381" 0.00127758200650242 0.00565567740260908 0.00339369404275551 "AVPR1A/ADA/ABAT/ACVR2A/AVP" 5 +"GO:0044241" "GO:0044241" "lipid digestion" "5/743" "20/17381" 0.00127758200650242 0.00565567740260908 0.00339369404275551 "APOA4/CD36/APOA1/APOA2/AQP1" 5 +"GO:0051187" "GO:0051187" "cofactor catabolic process" "5/743" "20/17381" 0.00127758200650242 0.00565567740260908 0.00339369404275551 "BLVRB/ACAT1/BLVRA/AMBP/CBR3" 5 +"GO:0007009" "GO:0007009" "plasma membrane organization" "10/743" "75/17381" 0.00128783911246028 0.00569621145895894 0.00341801653779382 "AKT2/AKT1/ATP2A2/AR/CAV3/CAV1/MYRF/ANK3/CAV2/ANK2" 10 +"GO:0033059" "GO:0033059" "cellular pigmentation" "8/743" "51/17381" 0.00134011093044367 0.00591225410489852 0.00354765311150789 "BBS2/CDH3/AP1G1/SHROOM2/BBS4/BCL2/CD63/ASIP" 8 +"GO:0046148" "GO:0046148" "pigment biosynthetic process" "8/743" "51/17381" 0.00134011093044367 0.00591225410489852 0.00354765311150789 "ALAS2/ALAS1/CDH3/TSPO/ALAD/ADA/APRT/ASIP" 8 +"GO:0050432" "GO:0050432" "catecholamine secretion" "8/743" "51/17381" 0.00134011093044367 0.00591225410489852 0.00354765311150789 "AGT/ADRA2B/ADRA2C/ADRA2A/ABAT/AGTR2/ADORA2A/GRK2" 8 +"GO:0072331" "GO:0072331" "signal transduction by p53 class mediator" "23/743" "270/17381" 0.00135019963289937 0.00595168918249934 0.00357131616341176 "BDKRB2/CDKN1B/ATR/CDC25C/BRCA2/ATRX/CDK1/CD74/CCNB1/AKT1/BOK/CASP2/BAX/CDK2/CDKN1A/BARD1/BLM/BCL3/ATM/BRCA1/CDK5/CD44/PTTG1IP" 23 +"GO:0030218" "GO:0030218" "erythrocyte differentiation" "12/743" "102/17381" 0.00135482270618633 0.00596196227953376 0.00357748054403755 "ALAS2/CDK6/ACVR1B/ARNT/ADD1/ADAR/BCL6/ZFP36L1/ACVR2A/CASP3/BMP4/B2M" 12 +"GO:0032677" "GO:0032677" "regulation of interleukin-8 production" "9/743" "63/17381" 0.00135713846672285 0.00596196227953376 0.00357748054403755 "ANXA1/BPI/ANXA4/ARRB1/BCL3/APOA2/CD2/CD14/CD58" 9 +"GO:0072431" "GO:0072431" "signal transduction involved in mitotic G1 DNA damage checkpoint" "9/743" "63/17381" 0.00135713846672285 0.00596196227953376 0.00357748054403755 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM" 9 +"GO:1902400" "GO:1902400" "intracellular signal transduction involved in G1 DNA damage checkpoint" "9/743" "63/17381" 0.00135713846672285 0.00596196227953376 0.00357748054403755 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM" 9 +"GO:0046717" "GO:0046717" "acid secretion" "13/743" "116/17381" 0.00136710962206607 0.00600067200525184 0.00360070834792635 "ANXA1/BDKRB2/AVPR1A/APBA1/ABAT/AQP9/CCKBR/CCK/AGTR2/ADORA2A/AVP/AGXT/ADORA1" 13 +"GO:0001937" "GO:0001937" "negative regulation of endothelial cell proliferation" "7/743" "40/17381" 0.00137770835389828 0.00603695235514275 0.0036224784027808 "ACVRL1/APOE/KRIT1/CAV1/APOH/CAV2/ATP5A1" 7 +"GO:0003170" "GO:0003170" "heart valve development" "7/743" "40/17381" 0.00137770835389828 0.00603695235514275 0.0036224784027808 "BMP2/BMPR1A/BMPR2/PRDM1/ACVR1/JAG1/BMP4" 7 +"GO:1904589" "GO:1904589" "regulation of protein import" "17/743" "175/17381" 0.00138023155130047 0.00604289194414545 0.00362604245822102 "APP/CDK1/BMPR1A/AGER/CD27/CD36/BMP7/CDKN1A/RHOA/BCL3/AGTR2/PARP1/BMP6/CDH1/APOD/BMP4/ANGPT1" 17 +"GO:0048592" "GO:0048592" "eye morphogenesis" "15/743" "145/17381" 0.00138303844378134 0.00605006250766563 0.00363034516096895 "CALB1/SHROOM2/BBS4/FOXL2/PRDM1/BAX/FASLG/BMP7/BCL2/ALDH1A3/AQP1/AQP5/JAG1/BMP4/BAK1" 15 +"GO:1905954" "GO:1905954" "positive regulation of lipid localization" "10/743" "76/17381" 0.00142737655415033 0.00623874465179725 0.00374356404226837 "ANXA2/APOC4/SCARB1/APOE/ABCA1/CD36/C3/ACACB/BMP6/APOB" 10 +"GO:0045930" "GO:0045930" "negative regulation of mitotic cell cycle" "25/743" "305/17381" 0.00146632919102894 0.00638946613356482 0.0038340045957826 "CDKN1B/CDC25C/ATRX/CDK1/CCNB1/BUB1B/BUB1/APC/CASP2/BAX/CDK2/BMP7/CDKN2B/CDKN1A/ZFP36L2/BCL2/BCL6/BLM/ATM/ZFP36L1/BRCA1/BCL2L1/BMP4/CCND1/ABL1" 25 +"GO:0019882" "GO:0019882" "antigen processing and presentation" "20/743" "223/17381" 0.00146958625520747 0.00638946613356482 0.0038340045957826 "AP2B1/AP1B1/CD74/CD1E/ARF1/AP1G1/CD1A/CAPZB/CD36/CANX/CD1B/CD8A/CD1C/CAPZA2/AP2A1/CAPZA1/CALR/AP2A2/CD1D/B2M" 20 +"GO:0002828" "GO:0002828" "regulation of type 2 immune response" "6/743" "30/17381" 0.00147297257919668 0.00638946613356482 0.0038340045957826 "ANXA1/ARG2/CD74/BCL6/ARG1/CD86" 6 +"GO:0010800" "GO:0010800" "positive regulation of peptidyl-threonine phosphorylation" "6/743" "30/17381" 0.00147297257919668 0.00638946613356482 0.0038340045957826 "APP/CALM1/CALM3/AZU1/CALM2/BMP7" 6 +"GO:0032365" "GO:0032365" "intracellular lipid transport" "6/743" "30/17381" 0.00147297257919668 0.00638946613356482 0.0038340045957826 "ANXA2/ABCA2/ACACA/ABCA1/ACACB/SLC25A20" 6 +"GO:0044319" "GO:0044319" "wound healing, spreading of cells" "6/743" "30/17381" 0.00147297257919668 0.00638946613356482 0.0038340045957826 "ACVRL1/DDR1/RHOC/RHOA/CEACAM1/CD44" 6 +"GO:0045920" "GO:0045920" "negative regulation of exocytosis" "6/743" "30/17381" 0.00147297257919668 0.00638946613356482 0.0038340045957826 "ANXA1/ABR/BCR/ADRA2A/BRAF/CEACAM1" 6 +"GO:0070229" "GO:0070229" "negative regulation of lymphocyte apoptotic process" "6/743" "30/17381" 0.00147297257919668 0.00638946613356482 0.0038340045957826 "ARG2/CD74/CD27/ADA/BCL6/BMP4" 6 +"GO:0090505" "GO:0090505" "epiboly involved in wound healing" "6/743" "30/17381" 0.00147297257919668 0.00638946613356482 0.0038340045957826 "ACVRL1/DDR1/RHOC/RHOA/CEACAM1/CD44" 6 +"GO:0002700" "GO:0002700" "regulation of production of molecular mediator of immune response" "13/743" "117/17381" 0.00147933296495651 0.00640631639635978 0.00384411561032521 "CD74/BTK/CD36/APOA1/CD40/BCL6/APOA2/BST2/ARG1/CD28/CD40LG/B2M/ANGPT1" 13 +"GO:1902807" "GO:1902807" "negative regulation of cell cycle G1/S phase transition" "13/743" "117/17381" 0.00147933296495651 0.00640631639635978 0.00384411561032521 "CDKN1B/CDC25C/CDK1/CDKN2D/CCNB1/CASP2/BAX/CDK2/CDKN2B/CDKN1A/BCL2/ATM/CCND1" 13 +"GO:0051262" "GO:0051262" "protein tetramerization" "15/743" "146/17381" 0.00148213919777669 0.00641310229807223 0.00384818749642778 "ALDOA/ANXA2/CD74/CD79A/CD247/ACTN2/ACACA/CDA/CAT/ACHE/ACPP/ACADL/ALDH1A3/ACACB/ADSL" 15 +"GO:0042445" "GO:0042445" "hormone metabolic process" "18/743" "192/17381" 0.00151753465028708 0.00656077010462458 0.0039367956895281 "BMP2/ADM/SCARB1/AGT/TSPO/ALDH9A1/ARNT/ATP1A1/ASMT/AFP/ADH7/ADH4/ALDH1A1/ALDH1A3/AKR1B1/BMP6/BMP5/AANAT" 18 +"GO:0061035" "GO:0061035" "regulation of cartilage development" "9/743" "64/17381" 0.00152052594858413 0.00656821517856669 0.00394126311248853 "BMP2/ACVRL1/RUNX2/BMPR2/BMP1/BMPR1B/BMP6/NKX3-2/BMP4" 9 +"GO:0033673" "GO:0033673" "negative regulation of kinase activity" "23/743" "273/17381" 0.00156127578838049 0.00673861735185074 0.00404351308171059 "CDKN1B/CDKN2D/AKT1/APOE/APC/CAV3/ADAR/CBLB/BGN/ADARB1/BMP7/CDKN2B/CDKN1A/CAV1/CEACAM1/ADORA2A/CDKN1C/CASP3/CDKN2A/BMP4/CDKN2C/ABL1/CBL" 23 +"GO:0044839" "GO:0044839" "cell cycle G2/M phase transition" "22/743" "257/17381" 0.00159751866914597 0.00688356295822679 0.00413048781627644 "APP/CDC25C/CDK1/CCNH/CDK4/CDK6/CALM3/CCNB1/BACH1/CDK7/CALM2/CDK3/CDK2/CDKN2B/CDKN1A/CDC25B/BLM/ATM/BRCA1/CCNA2/CDC25A/CCND1" 22 +"GO:0050851" "GO:0050851" "antigen receptor-mediated signaling pathway" "22/743" "257/17381" 0.00159751866914597 0.00688356295822679 0.00413048781627644 "CD3G/CD4/CD79A/RUNX1/BTK/CD247/CD3E/BLK/CACNA1F/CD3D/BAX/CD19/ADA/CD79B/BCL2/BRAF/CD38/CBFB/CEACAM1/CD28/CACNB3/ABL1" 22 +"GO:0032459" "GO:0032459" "regulation of protein oligomerization" "7/743" "41/17381" 0.0016010571002303 0.00689307029425276 0.00413619270135685 "BID/FAS/APOE/BAX/RHOC/CCK/BIK" 7 +"GO:0031440" "GO:0031440" "regulation of mRNA 3'-end processing" "5/743" "21/17381" 0.00161841751454165 0.00695046525954609 0.00417063259916826 "CCNB1/CCNT1/CDK9/BARD1/ZFP36L1" 5 +"GO:0032462" "GO:0032462" "regulation of protein homooligomerization" "5/743" "21/17381" 0.00161841751454165 0.00695046525954609 0.00417063259916826 "BID/FAS/APOE/RHOC/BIK" 5 +"GO:0042094" "GO:0042094" "interleukin-2 biosynthetic process" "5/743" "21/17381" 0.00161841751454165 0.00695046525954609 0.00417063259916826 "CD4/CD80/CD3E/CD28/CD86" 5 +"GO:0051250" "GO:0051250" "negative regulation of lymphocyte activation" "14/743" "133/17381" 0.00167026247691018 0.00716717107629368 0.00430066710909054 "ANXA1/AXL/ARG2/FAS/CD74/BTK/PRDM1/BCL6/CEACAM1/ATM/ADORA2A/CASP3/ARG1/BMP4" 14 +"GO:0032388" "GO:0032388" "positive regulation of intracellular transport" "27/743" "342/17381" 0.00167452903125887 0.00717952587967247 0.0043080806193814 "APP/ANXA2/BID/CDK1/AKT2/BMPR1A/AGER/CDH3/ARF1/BAD/ACTN2/BOK/CD27/CDC42/BAX/ACTL6A/ADORA2B/CASP8/BCL2/ANK3/RHOA/PARP1/BMP6/CDH1/CDK5/BMP4/BAK1" 27 +"GO:0048678" "GO:0048678" "response to axon injury" "9/743" "65/17381" 0.00169933980527034 0.0072605389316739 0.00435669257023911 "AIF1/CDK1/TSPO/BAX/APOA1/BCL2/BRAF/APOD/ARG1" 9 +"GO:0072413" "GO:0072413" "signal transduction involved in mitotic cell cycle checkpoint" "9/743" "65/17381" 0.00169933980527034 0.0072605389316739 0.00435669257023911 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM" 9 +"GO:1902402" "GO:1902402" "signal transduction involved in mitotic DNA damage checkpoint" "9/743" "65/17381" 0.00169933980527034 0.0072605389316739 0.00435669257023911 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM" 9 +"GO:1902403" "GO:1902403" "signal transduction involved in mitotic DNA integrity checkpoint" "9/743" "65/17381" 0.00169933980527034 0.0072605389316739 0.00435669257023911 "CDKN1B/CDC25C/CDK1/CCNB1/CASP2/BAX/CDK2/CDKN1A/ATM" 9 +"GO:0021549" "GO:0021549" "cerebellum development" "11/743" "91/17381" 0.00170043926283841 0.0072605389316739 0.00435669257023911 "AARS/ARCN1/RERE/CD3E/ATP7A/ATIC/ABAT/AGTR2/CDK5/CBLN1/ABL1" 11 +"GO:0071456" "GO:0071456" "cellular response to hypoxia" "18/743" "194/17381" 0.00170452985153741 0.00727200493133232 0.0043635727531005 "BNIP3L/CCNB1/AKT1/BACH1/CA9/ARNT/BAD/CD34/CASR/ATP7A/BMP7/BCL2/AQP3/AQP1/ZFP36L1/CCNA2/ADAM8/BNIP3" 18 +"GO:0022612" "GO:0022612" "gland morphogenesis" "13/743" "119/17381" 0.0017267756513773 0.00733106316060844 0.0043990106938815 "DDR1/AR/CAV3/AREG/CDC42/BAX/CAPN1/BMP7/CAV1/BCL2/CEACAM1/ARG1/BMP4" 13 +"GO:0086002" "GO:0086002" "cardiac muscle cell action potential involved in contraction" "8/743" "53/17381" 0.00173066997252139 0.00733106316060844 0.0043990106938815 "CACNA1C/ATP1A1/CAV3/CACNA2D1/CAV1/CACNA1D/ANK2/CACNB2" 8 +"GO:0010885" "GO:0010885" "regulation of cholesterol storage" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "SCARB1/ABCA1/CD36/APOB" 4 +"GO:0032230" "GO:0032230" "positive regulation of synaptic transmission, GABAergic" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "ADRA1A/ADORA2A/CA2/CA7" 4 +"GO:0035815" "GO:0035815" "positive regulation of renal sodium excretion" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "AVPR1A/AGT/AGTR2/ADORA2A" 4 +"GO:0045579" "GO:0045579" "positive regulation of B cell differentiation" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "BTK/BAD/CD27/PRDM1" 4 +"GO:0060576" "GO:0060576" "intestinal epithelial cell development" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "KLF5/PRDM1/CDKN1A/NKX3-2" 4 +"GO:0071280" "GO:0071280" "cellular response to copper ion" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "AQP2/AOC1/ATP7A/AQP1" 4 +"GO:0071285" "GO:0071285" "cellular response to lithium ion" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "CDKN1B/FAS/CALR/CDH1" 4 +"GO:0072044" "GO:0072044" "collecting duct development" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "AQP2/CALB1/AKR1B1/BMP4" 4 +"GO:0090399" "GO:0090399" "replicative senescence" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "ATR/CDKN1A/ATM/CDKN2A" 4 +"GO:0097284" "GO:0097284" "hepatocyte apoptotic process" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "BID/FAS/ARF6/BCL2L1" 4 +"GO:0097296" "GO:0097296" "activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "FAS/BAX/FASLG/CASP8" 4 +"GO:1902514" "GO:1902514" "regulation of calcium ion transmembrane transport via high voltage-gated calcium channel" "4/743" "13/17381" 0.00173820570010948 0.00733106316060844 0.0043990106938815 "CAMK2D/CACNA2D1/CACNB1/CACNB2" 4 +"GO:0006007" "GO:0006007" "glucose catabolic process" "6/743" "31/17381" 0.00176136116565584 0.0074045849165467 0.00444312748615566 "ALDOC/ALDOA/BAD/ACTN3/BPGM/ALDOB" 6 +"GO:0032892" "GO:0032892" "positive regulation of organic acid transport" "6/743" "31/17381" 0.00176136116565584 0.0074045849165467 0.00444312748615566 "AVPR1A/AGT/ABAT/CCK/ADORA2A/AVP" 6 +"GO:0050869" "GO:0050869" "negative regulation of B cell activation" "6/743" "31/17381" 0.00176136116565584 0.0074045849165467 0.00444312748615566 "FAS/BTK/PRDM1/BCL6/ATM/CASP3" 6 +"GO:0090504" "GO:0090504" "epiboly" "6/743" "31/17381" 0.00176136116565584 0.0074045849165467 0.00444312748615566 "ACVRL1/DDR1/RHOC/RHOA/CEACAM1/CD44" 6 +"GO:0042157" "GO:0042157" "lipoprotein metabolic process" "18/743" "195/17381" 0.00180509434510195 0.00758227535381703 0.00454975078439059 "ALPL/APOC3/APOE/APOA4/ALPI/ABCA1/ART3/APOA1/APOA2/ATM/ALOX12B/BST1/APOBEC1/APOD/APOC1/ALPPL2/ART4/APOB" 18 +"GO:0031331" "GO:0031331" "positive regulation of cellular catabolic process" "30/743" "396/17381" 0.00181016112323765 0.00759739157563249 0.00455882128616646 "BNIP3L/APOC2/ADRB2/CDK1/ENTPD5/AKT2/CCNB1/BUB1B/AKT1/APOE/CD81/ARNT/BAD/APOA4/ABCD2/CAV3/AADAC/CDC20/BAX/APOA1/ADRA2A/ZFP36L2/CAV1/CBFA2T3/ATM/ZFP36L1/ADAM8/BNIP3/PTTG1IP/CDC27" 30 +"GO:0008361" "GO:0008361" "regulation of cell size" "15/743" "149/17381" 0.00181580768508167 0.00761491472471444 0.00456933606669872 "CDK4/AKT1/APOE/ANXA7/ADD1/CAV3/ATP7A/BMPR2/BDNF/ARHGAP4/RHOA/AQP1/CDK5/CDH4/ABL1" 15 +"GO:0048638" "GO:0048638" "regulation of developmental growth" "25/743" "310/17381" 0.00183287774678589 0.00768027719807041 0.00460855687450958 "APP/BBS2/ADRB2/CDK1/CDK4/CCNB1/AKT1/BMPR1A/APOE/AR/CAV3/ADRB3/BBS4/BMPR2/CAPN3/BDNF/ACTN3/ADRB1/ARHGAP4/BCL2/ACACB/CDK5/BMP4/CDH4/ABL1" 25 +"GO:0010883" "GO:0010883" "regulation of lipid storage" "7/743" "42/17381" 0.0018515889604181 0.00773988115522104 0.0046443222797665 "APOC4/SCARB1/ABCA1/CD36/C3/ACACB/APOB" 7 +"GO:0090342" "GO:0090342" "regulation of cell aging" "7/743" "42/17381" 0.0018515889604181 0.00773988115522104 0.0046443222797665 "CDK6/ARG2/BMPR1A/BCL6/ARNTL/CDKN2A/ABL1" 7 +"GO:2000351" "GO:2000351" "regulation of endothelial cell apoptotic process" "7/743" "42/17381" 0.0018515889604181 0.00773988115522104 0.0046443222797665 "KRIT1/FASLG/BRAF/CD40/CD40LG/ABL1/ANGPT1" 7 +"GO:0050853" "GO:0050853" "B cell receptor signaling pathway" "11/743" "92/17381" 0.00185854944438728 0.00776270651711395 0.00465801865761223 "CD79A/RUNX1/BTK/BLK/BAX/CD19/CD79B/BCL2/CD38/CBFB/ABL1" 11 +"GO:0043500" "GO:0043500" "muscle adaptation" "12/743" "106/17381" 0.00189069449351235 0.00789060000316648 0.00473476125285352 "AIF1/CAMK2B/AGT/ATP2A2/ACTA1/ATP2B4/CAMK2D/CAV3/CDK9/ACTN3/CAMK2G/PARP1" 12 +"GO:0061180" "GO:0061180" "mammary gland epithelium development" "9/743" "66/17381" 0.00189460687309939 0.00790055646115178 0.00474073563394818 "BRCA2/DDR1/AKT2/AKT1/AR/CAV3/AREG/BAX/CCND1" 9 +"GO:0032956" "GO:0032956" "regulation of actin cytoskeleton organization" "24/743" "294/17381" 0.00190720172446852 0.00794667385195215 0.00476840841357922 "ABL2/ARHGDIA/ARF1/ACTN2/ADD1/CAV3/BBS4/ADD2/CAPZB/CDC42/APOA1/CAPG/ALOX15/BRAF/CAPZA2/CAPZA1/RHOA/ARHGAP6/ARF6/BST1/BST2/CDK5/ARHGDIB/ABL1" 24 +"GO:0002064" "GO:0002064" "epithelial cell development" "18/743" "196/17381" 0.0019106157798046 0.00795449449757748 0.00477310119864807 "KLF5/ATRX/BFSP1/CDK6/ACTA2/BAD/AR/ADD1/CDH5/PRDM1/CDC42/CDKN1A/ARNTL/BMP6/BMP5/NKX3-2/JAG1/BMP4" 18 +"GO:0031102" "GO:0031102" "neuron projection regeneration" "8/743" "54/17381" 0.0019570193120598 0.00814113741150279 0.00488509643812524 "ADM/TSPO/APOE/APOA4/APOA1/BCL2/BRAF/APOD" 8 +"GO:0002438" "GO:0002438" "acute inflammatory response to antigenic stimulus" "5/743" "22/17381" 0.00202155089793549 0.00838263293014116 0.00503000602978214 "CD6/BTK/SERPINC1/C3/ADCYAP1" 5 +"GO:0030325" "GO:0030325" "adrenal gland development" "5/743" "22/17381" 0.00202155089793549 0.00838263293014116 0.00503000602978214 "TSPO/NR0B1/ASCL1/APOA1/CDKN1C" 5 +"GO:0032799" "GO:0032799" "low-density lipoprotein receptor particle metabolic process" "5/743" "22/17381" 0.00202155089793549 0.00838263293014116 0.00503000602978214 "ANXA2/AP2B1/APOE/AP2A1/AP2A2" 5 +"GO:1903306" "GO:1903306" "negative regulation of regulated secretory pathway" "5/743" "22/17381" 0.00202155089793549 0.00838263293014116 0.00503000602978214 "ABR/BCR/ADRA2A/BRAF/CEACAM1" 5 +"GO:0086019" "GO:0086019" "cell-cell signaling involved in cardiac conduction" "6/743" "32/17381" 0.00209060299051114 0.00866202600151734 0.00519765608023924 "CACNA1C/CACNA2D1/CACNA1D/CASQ2/ANK2/CACNB2" 6 +"GO:0032602" "GO:0032602" "chemokine production" "10/743" "80/17381" 0.00211356299650624 0.00874315628051141 0.00524633837325373 "ARG2/CD74/AZU1/AGER/C5/AIRE/ADORA2B/ADCYAP1/APOD/ALOX15B" 10 +"GO:1901379" "GO:1901379" "regulation of potassium ion transmembrane transport" "10/743" "80/17381" 0.00211356299650624 0.00874315628051141 0.00524633837325373 "ATP1B3/ACTN2/ATP1B2/CAV3/CAV1/ANK3/CACNA1D/ATP1B1/CASQ2/ANK2" 10 +"GO:0002437" "GO:0002437" "inflammatory response to antigenic stimulus" "7/743" "43/17381" 0.00213146922382127 0.00880315501458506 0.00528234066473957 "CD6/AHCY/BTK/SERPINC1/C3/ADCYAP1/CD28" 7 +"GO:0043268" "GO:0043268" "positive regulation of potassium ion transport" "7/743" "43/17381" 0.00213146922382127 0.00880315501458506 0.00528234066473957 "ATP1B3/ACTN2/ATP1B2/ADRA2A/ATP1B1/ANK2/ADORA1" 7 +"GO:0034612" "GO:0034612" "response to tumor necrosis factor" "24/743" "297/17381" 0.0021802803644224 0.00899039911225969 0.0053946966450376 "BIRC2/CASP1/CASP4/FAS/CALCA/AKT1/CD27/APOA1/TNFRSF8/ZFP36L2/CASP8/TNFSF8/CD40/CD14/BIRC3/ZFP36L1/CASP3/BRCA1/CD58/APOB/ADAM10/CD40LG/TNFRSF17/CD70" 24 +"GO:0051170" "GO:0051170" "nuclear import" "24/743" "297/17381" 0.0021802803644224 0.00899039911225969 0.0053946966450376 "APP/CDK1/AGT/AKT1/BMPR1A/AGER/RERE/CD27/CD36/CBLB/BMP7/CDKN1A/BCL6/RHOA/BCL3/AGTR2/PARP1/ARNTL/BMP6/CDH1/APOD/BMP4/PTTG1IP/ANGPT1" 24 +"GO:0022600" "GO:0022600" "digestive system process" "11/743" "94/17381" 0.00221072001916424 0.00910865931462974 0.0054656587801999 "SCARB1/APOA4/SERPINA3/ACO1/CD36/APOA1/ADRA2A/CCKBR/APOA2/AQP1/AQP5" 11 +"GO:0043900" "GO:0043900" "regulation of multi-organism process" "29/743" "385/17381" 0.00232744190368524 0.00958195055813135 0.00574965759399695 "BIRC2/ANXA2/CD4/ARG2/CD74/ACVR1B/APOE/BAD/CCNT1/CRISP1/ADAR/CD36/PRDM1/CDK9/ADA/ADARB1/CAMP/CAV1/BCL2/CALR/BST2/BIRC3/BMP6/CAV2/ARG1/CD28/APCS/ARHGDIB/C1QBP" 29 +"GO:0051851" "GO:0051851" "modification by host of symbiont morphology or physiology" "9/743" "68/17381" 0.00233877722671352 0.00959818820817529 0.00575940100973651 "ANXA2/AZU1/APOE/CCNT1/CAMP/AQP1/CAV2/ARG1/APCS" 9 +"GO:0002829" "GO:0002829" "negative regulation of type 2 immune response" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "ANXA1/ARG2/BCL6/ARG1" 4 +"GO:0006534" "GO:0006534" "cysteine metabolic process" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "CDO1/AHCY/CBS/AGXT" 4 +"GO:0010663" "GO:0010663" "positive regulation of striated muscle cell apoptotic process" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "AGT/CAMK2D/BNIP3/CAMK2A" 4 +"GO:0010666" "GO:0010666" "positive regulation of cardiac muscle cell apoptotic process" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "AGT/CAMK2D/BNIP3/CAMK2A" 4 +"GO:0030299" "GO:0030299" "intestinal cholesterol absorption" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "APOA4/CD36/APOA1/APOA2" 4 +"GO:0034111" "GO:0034111" "negative regulation of homotypic cell-cell adhesion" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "CD9/ALOX12/ABAT/CEACAM1" 4 +"GO:0036295" "GO:0036295" "cellular response to increased oxygen levels" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "FAS/ATP6V1A/ATP6AP1/CAV1" 4 +"GO:0050667" "GO:0050667" "homocysteine metabolic process" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "AHCY/BLMH/CBS/BHMT" 4 +"GO:0060712" "GO:0060712" "spongiotrophoblast layer development" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "ADM/AKT1/ASCL2/ZFP36L1" 4 +"GO:0098856" "GO:0098856" "intestinal lipid absorption" "4/743" "14/17381" 0.00235178795129783 0.00959818820817529 0.00575940100973651 "APOA4/CD36/APOA1/APOA2" 4 +"GO:0072006" "GO:0072006" "nephron development" "14/743" "138/17381" 0.00236596019635881 0.00964841924047031 0.00578954218345028 "BMP2/CALB1/AGT/ACAT1/ACTA2/CD34/BMP7/BCL2/AGTR2/AQP1/ANGPT2/JAG1/BMP4/ANGPT1" 14 +"GO:0046822" "GO:0046822" "regulation of nucleocytoplasmic transport" "19/743" "216/17381" 0.00237922003745677 0.00969485330223527 0.00581740498176335 "APP/CDK1/BMPR1A/AGER/CD27/CD36/BMP7/CDKN1A/BARD1/RHOA/BCL3/AGTR2/PARP1/BMP6/CDH1/APOD/CDK5/BMP4/ANGPT1" 19 +"GO:1903793" "GO:1903793" "positive regulation of anion transport" "7/743" "44/17381" 0.00244292788783975 0.00994661826874171 0.00596847676436065 "AVPR1A/AGT/APOE/ABAT/CCK/ADORA2A/AVP" 7
--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/test-data/genedf.txt Sun Apr 28 07:28:12 2019 -0400 @@ -0,0 +1,1037 @@ +"SYMBOL" "ENTREZID" +"ARX" "170302" +"CDR1" "1038" +"TP73" "7161" +"TCEAL7" "56849" +"SNX12" "29934" +"CSAG4" "100130935" +"MAGEC2" "51438" +"TGIF2LX" "90316" +"LAMC2" "3918" +"FGF13" "2258" +"KLHL34" "257240" +"SLITRK2" "84631" +"ACTA1" "58" +"CITED1" "4435" +"BCOR" "54880" +"PBDC1" "51260" +"TTC39A" "22996" +"KCNE5" "23630" +"TAF7L" "54457" +"GABRA3" "2556" +"PAGE2B" "389860" +"PRRX1" "5396" +"IL12RB2" "3595" +"MAGEB6" "158809" +"BARHL2" "343472" +"ESRRG" "2104" +"MAGEB16" "139604" +"NGF" "4803" +"FOXD2" "2306" +"HTR2C" "3358" +"FAM47B" "170062" +"LINC00982" "440556" +"PGBD5" "79605" +"FAM47C" "442444" +"MAGEA1" "4100" +"MID1" "4281" +"TAL1" "6886" +"MIR5087" "100847044" +"FAM47A" "158724" +"NPHP4" "261734" +"GPRASP1" "9737" +"MIR503" "574506" +"RSG1" "79363" +"ARSH" "347527" +"OBSCN-AS1" "574407" +"TIMP1" "7076" +"KIAA1324" "57535" +"NBPF13P" "644861" +"HES5" "388585" +"FHL1" "2273" +"CAMK2N1" "55450" +"DCAF12L1" "139170" +"CEP85" "64793" +"BTBD19" "149478" +"ALX3" "257" +"PAGE3" "139793" +"SEMA6C" "10500" +"TBX15" "6913" +"TACSTD2" "4070" +"OPRD1" "4985" +"MANEAL" "149175" +"CFAP45" "25790" +"UBL4B" "164153" +"PLCH2" "9651" +"H2BFM" "286436" +"NUDT10" "170685" +"BEST4" "266675" +"CCNQ" "92002" +"MIR507" "574512" +"COL11A1" "1301" +"SLC30A2" "7780" +"GNG4" "2786" +"MIR205HG" "642587" +"IRS4" "8471" +"OR2M3" "127062" +"MIR890" "100126303" +"XKR8" "55113" +"DMBX1" "127343" +"PHKA1" "5255" +"HPCAL4" "51440" +"UTP14A" "10813" +"AJAP1" "55966" +"CIART" "148523" +"LRRC7" "57554" +"COL9A2" "1298" +"ARTN" "9048" +"RUNX3" "864" +"LHX9" "56956" +"COL24A1" "255631" +"PCSK9" "255738" +"TRIM11" "81559" +"WASF2" "10163" +"TEX13A" "56157" +"MIR223" "407008" +"EGFL6" "25975" +"VENTXP1" "139538" +"MIR106A" "406899" +"MCOLN2" "255231" +"ARHGAP36" "158763" +"ZNF185" "7739" +"ERAS" "3266" +"LCE1A" "353131" +"OR2T29" "343563" +"PAGE1" "8712" +"WDR64" "128025" +"MST1L" "11223" +"TMEM35A" "59353" +"C1QTNF12" "388581" +"MAGEB2" "4113" +"MIR892A" "100126342" +"CXorf51B" "100133053" +"CAPN2" "824" +"PRAF2" "11230" +"DMRTA2" "63950" +"CR1L" "1379" +"PAGE5" "90737" +"AMER1" "139285" +"SLC2A1" "6513" +"TTC34" "100287898" +"SLITRK4" "139065" +"BRDTP1" "643486" +"MCF2" "4168" +"ACTRT2" "140625" +"TCEAL6" "158931" +"MIR548AP" "100847084" +"MIR200B" "406984" +"LUZP4" "51213" +"MAGEA4" "4103" +"TSPYL2" "64061" +"OR6K2" "81448" +"VCX2" "51480" +"TEX13C" "100129520" +"OR2M5" "127059" +"VCX3B" "425054" +"TCEAL4" "79921" +"CAMTA1" "23261" +"SYTL1" "84958" +"ADAMTS4" "9507" +"SUSD4" "55061" +"OR2C3" "81472" +"PODN" "127435" +"NLGN4X" "57502" +"NT5C1A" "84618" +"CLSTN1" "22883" +"DYNLT3" "6990" +"EDN2" "1907" +"MIR510" "574515" +"OR1C1" "26188" +"BEND2" "139105" +"GIPC2" "54810" +"H6PD" "9563" +"MAGEA10-MAGEA5" "100533997" +"BRWD3" "254065" +"LINC01341" "149134" +"SLC16A2" "6567" +"FAAP20" "199990" +"FAM163A" "148753" +"HNRNPCL2" "440563" +"FOXD3" "27022" +"PGRMC1" "10857" +"NUF2" "83540" +"ZDHHC15" "158866" +"NEXMIF" "340533" +"NADK" "65220" +"LELP1" "149018" +"MT1HL1" "645745" +"TTC3P1" "286495" +"FAM229A" "100128071" +"ADGRB2" "576" +"TGIF2LY" "90655" +"MIR5191" "100847050" +"SATL1" "340562" +"SAGE1" "55511" +"NAV1" "89796" +"MXRA5" "25878" +"EBNA1BP2" "10969" +"TNFRSF25" "8718" +"ASB12" "142689" +"MAGEE2" "139599" +"YOD1" "55432" +"AR" "367" +"TDRD5" "163589" +"MAGEA5" "4104" +"HEPH" "9843" +"RPS6KA3" "6197" +"AFF2" "2334" +"MIR4251" "100422968" +"PNMA5" "114824" +"MIR4254" "100423028" +"S100A7L2" "645922" +"NKAP" "79576" +"MAGEB3" "4114" +"XAGE5" "170627" +"SSX9" "280660" +"XKRX" "402415" +"XAGE3" "170626" +"LINC01777" "284661" +"AGRN" "375790" +"PRKX" "5613" +"NTRK1" "4914" +"SLC6A9" "6536" +"TNFRSF18" "8784" +"MAGEB18" "286514" +"GRIA3" "2892" +"CAPN8" "388743" +"SOWAHD" "347454" +"VSIG1" "340547" +"EDEM3" "80267" +"HIST3H2A" "92815" +"GPM6B" "2824" +"CACNA1E" "777" +"DIRAS3" "9077" +"PLXNA2" "5362" +"GLIS1" "148979" +"ASTN1" "460" +"LOC389895" "389895" +"MID1IP1" "58526" +"SPANXN5" "494197" +"ATRX" "546" +"MAGEE1" "57692" +"MMP23B" "8510" +"CD1C" "911" +"CROCCP3" "114819" +"C1orf210" "149466" +"OR2G6" "391211" +"LINC00862" "554279" +"MID2" "11043" +"WNT2B" "7482" +"LHX8" "431707" +"KCNC4" "3749" +"TMEM200B" "399474" +"TMEM61" "199964" +"FAM183A" "440585" +"ZBTB18" "10472" +"MIR4417" "100616489" +"FABP3" "2170" +"MAMLD1" "10046" +"PPP4R3C" "139420" +"LOC100132111" "100132111" +"F9" "2158" +"SRPK3" "26576" +"MIR4677" "100616343" +"CYP4Z2P" "163720" +"TP73-AS1" "57212" +"TMEM51-AS1" "200197" +"SSX7" "280658" +"KCNA2" "3737" +"TEX28" "1527" +"LIN28A" "79727" +"PRSS38" "339501" +"S100A12" "6283" +"FTH1P18" "441490" +"MIR4689" "100616421" +"KIAA1522" "57648" +"GPR50" "9248" +"RHOU" "58480" +"PRAMEF20" "645425" +"TSIX" "9383" +"L1CAM" "3897" +"MIR488" "574441" +"FCRL1" "115350" +"CD1A" "909" +"PRPS1" "5631" +"NTNG1" "22854" +"FAAHP1" "729041" +"TRPC5" "7224" +"MYCBP" "26292" +"LOC728989" "728989" +"NCMAP" "400746" +"NXF5" "55998" +"GABRE" "2564" +"BEX5" "340542" +"CSAG1" "158511" +"FRMD8P1" "83957" +"ZNF648" "127665" +"NXT2" "55916" +"LCE2C" "353140" +"KAZN" "23254" +"LINC01142" "284688" +"CD53" "963" +"RYR2" "6262" +"TSSK3" "81629" +"FCER1A" "2205" +"AKAP4" "8852" +"KLHDC7A" "127707" +"CD164L2" "388611" +"BEX1" "55859" +"SLC7A3" "84889" +"ZCCHC18" "644353" +"ITLN2" "142683" +"HEYL" "26508" +"LPAR4" "2846" +"OR13H1" "347468" +"LCE4A" "199834" +"OMA1" "115209" +"MIR384" "494333" +"ZYG11A" "440590" +"SOX3" "6658" +"FMO9P" "116123" +"TSHB" "7252" +"C1orf115" "79762" +"NAP1L6" "645996" +"FCRL3" "115352" +"NBPF3" "84224" +"OR2M1P" "388762" +"MIR4666A" "100616308" +"AADACL3" "126767" +"OR2M4" "26245" +"EPHX1" "2052" +"TCEA3" "6920" +"NR5A2" "2494" +"OR2G2" "81470" +"SRD5A1P1" "6719" +"SGIP1" "84251" +"DESI2" "51029" +"IL6R" "3570" +"PLD5" "200150" +"SH3D21" "79729" +"TMSB15A" "11013" +"TCEAL2" "140597" +"AHDC1" "27245" +"MAP1LC3C" "440738" +"MEX3A" "92312" +"ARF1" "375" +"A3GALT2" "127550" +"VCX3A" "51481" +"OR2M2" "391194" +"PRPS2" "5634" +"IRF6" "3664" +"EFNA1" "1942" +"L1TD1" "54596" +"MIR888" "100126306" +"BSDC1" "55108" +"FAM46D" "169966" +"CYP4Z1" "199974" +"MOB3C" "148932" +"MIR4427" "100616390" +"MTMR8" "55613" +"FCRL5" "83416" +"LINC00624" "100289211" +"HLX" "3142" +"BMP8A" "353500" +"TCHHL1" "126637" +"LINC01699" "100287948" +"WRAP73" "49856" +"CASZ1" "54897" +"PROX1" "5629" +"MIR9-1" "407046" +"C1orf87" "127795" +"TMEM269" "100129924" +"LINC01761" "440594" +"OR10J5" "127385" +"NCSTN" "23385" +"DENND2D" "79961" +"RGSL1" "353299" +"ACOT7" "11332" +"PBX1" "5087" +"ST6GALNAC5" "81849" +"CRABP2" "1382" +"FAM212B-AS1" "100506343" +"C1orf61" "10485" +"TAS1R2" "80834" +"FOXE3" "2301" +"MATN1-AS1" "100129196" +"PTCHD1" "139411" +"ZNF678" "339500" +"COL16A1" "1307" +"OR10R2" "343406" +"RAI2" "10742" +"OR10K2" "391107" +"PTCH2" "8643" +"SH2D1A" "4068" +"LANCL3" "347404" +"ARHGAP6" "395" +"TNFRSF14-AS1" "115110" +"HNRNPCL3" "649330" +"LOC645166" "645166" +"LINC00582" "100287814" +"MROH9" "80133" +"DACH2" "117154" +"LRIF1" "55791" +"KCND3" "3752" +"PRRG3" "79057" +"BRS3" "680" +"FCGR1A" "2209" +"CD1B" "910" +"SMARCA1" "6594" +"OR2G3" "81469" +"ALG13" "79868" +"RNF207" "388591" +"SLC2A5" "6518" +"LINC00629" "100506757" +"SERPINA7" "6906" +"HMGCS2" "3158" +"SIKE1" "80143" +"VWA5B1" "127731" +"BRINP2" "57795" +"MIR514A2" "574517" +"FAAH2" "158584" +"LINC01343" "339442" +"KIRREL1" "55243" +"GYG2P1" "352887" +"HMGB4" "127540" +"LINC01346" "728716" +"RGS7" "6000" +"NLRP3" "114548" +"C1QC" "714" +"SKINT1L" "391037" +"MEGF6" "1953" +"ZNF496" "84838" +"MIR508" "574513" +"H3F3AP4" "440926" +"OTUD6A" "139562" +"PKLR" "5313" +"TNFSF18" "8995" +"SYT2" "127833" +"PRAMEF1" "65121" +"OLFML2B" "25903" +"PRAMEF11" "440560" +"DUSP9" "1852" +"LRRC38" "126755" +"ARHGEF19" "128272" +"MIR320D2" "100302169" +"KCNQ4" "9132" +"CHD5" "26038" +"KLF8" "11279" +"GPR101" "83550" +"AMELX" "265" +"CADM3-AS1" "100131825" +"FTHL17" "53940" +"MIR135B" "442891" +"HSPA6" "3310" +"KIF21B" "23046" +"HIST2H2BA" "337875" +"CLCN4" "1183" +"ARID1A" "8289" +"LOC100130331" "100130331" +"SYN1" "6853" +"MIR651" "723779" +"ENSA" "2029" +"ATXN3L" "92552" +"MACF1" "23499" +"IGSF8" "93185" +"OR2T5" "401993" +"GPR137B" "7107" +"MUM1L1" "139221" +"SSU72" "29101" +"LOC100505795" "100505795" +"MAP3K21" "84451" +"LDLRAD2" "401944" +"MAP10" "54627" +"OR2T33" "391195" +"SELL" "6402" +"RTL5" "340526" +"FMR1NB" "158521" +"TSPY2" "64591" +"AIFM1" "9131" +"TMEM240" "339453" +"KIAA1614" "57710" +"EFNA3" "1944" +"ESX1" "80712" +"SLC45A1" "50651" +"TTC22" "55001" +"PAGE4" "9506" +"KPRP" "448834" +"GJC2" "57165" +"CD5L" "922" +"TNFRSF8" "943" +"CD1E" "913" +"SPRR2F" "6705" +"PADI4" "23569" +"IBA57" "200205" +"TSPAN1" "10103" +"ARSF" "416" +"MIR4255" "100422898" +"TNMD" "64102" +"MIR891B" "100126304" +"BCORL1" "63035" +"RPS7P5" "645884" +"RAP1A" "5906" +"PIN4" "5303" +"PRKCZ" "5590" +"S100A9" "6280" +"MIR891A" "100126341" +"C8B" "732" +"RNF220" "55182" +"SMYD3" "64754" +"C1orf68" "100129271" +"LINC01364" "100505768" +"LCE6A" "448835" +"RGS4" "5999" +"JUN" "3725" +"FCRL2" "79368" +"CT83" "203413" +"CNIH3" "149111" +"GSPT2" "23708" +"KIAA0040" "9674" +"LCE1B" "353132" +"TEX13B" "56156" +"LINC00466" "199899" +"ACTL8" "81569" +"TSC22D3" "1831" +"DUSP27" "92235" +"CCDC185" "164127" +"PLS3" "5358" +"APCS" "325" +"MARC1" "64757" +"XIST" "7503" +"DPH5" "51611" +"CLCC1" "23155" +"OR2W5" "441932" +"CYP4A22" "284541" +"MBTPS2" "51360" +"SLC6A17" "388662" +"KCTD3" "51133" +"RTL4" "340595" +"TDRKH" "11022" +"OR6K3" "391114" +"C1orf229" "388759" +"FAM9A" "171482" +"HES3" "390992" +"SPRR2B" "6701" +"TADA1" "117143" +"LMX1A" "4009" +"FTSJ1" "24140" +"FAM155B" "27112" +"ALAS2" "212" +"SPRR2C" "6702" +"SPANXN3" "139067" +"GABRQ" "55879" +"ZIC3" "7547" +"NRK" "203447" +"LRRC8D" "55144" +"OR14A16" "284532" +"PUDP" "8226" +"FOXR2" "139628" +"C1QB" "713" +"MYOG" "4656" +"PTPRU" "10076" +"CD34" "947" +"MIR4684" "100616391" +"C1orf216" "127703" +"SF3A3" "10946" +"CITED4" "163732" +"OR13G1" "441933" +"SPRR2G" "6706" +"NFASC" "23114" +"SPSB1" "80176" +"CSTF2" "1478" +"OR2T3" "343173" +"GPR173" "54328" +"NHSL2" "340527" +"KCNK2" "3776" +"AZIN2" "113451" +"GPR88" "54112" +"TMEM255A" "55026" +"MIR676" "100500887" +"TGFBR3" "7049" +"SHCBP1L" "81626" +"PCDH11X" "27328" +"EFNB1" "1947" +"SPATA21" "374955" +"PGLYRP4" "57115" +"MIR4422" "100616272" +"VSIG4" "11326" +"CXorf21" "80231" +"SPRR2D" "6703" +"PGLYRP3" "114771" +"ZNF275" "10838" +"UTP11" "51118" +"UBXN10" "127733" +"SHROOM2" "357" +"GALNT2" "2590" +"LOR" "4014" +"C1orf194" "127003" +"DISP3" "57540" +"FAM89A" "375061" +"RLIM" "51132" +"MAB21L3" "126868" +"EDA" "1896" +"MXRA8" "54587" +"VAMP3" "9341" +"CRP" "1401" +"CNKSR2" "22866" +"DGKK" "139189" +"DFFB" "1677" +"SLC44A3" "126969" +"GOLT1A" "127845" +"RHOC" "389" +"MIR4671" "100616380" +"OR10K1" "391109" +"LRRN2" "10446" +"CTTNBP2NL" "55917" +"FAM3A" "60343" +"MIR892B" "100126307" +"SYDE2" "84144" +"DCAF12L2" "340578" +"XPNPEP2" "7512" +"PRAMEF4" "400735" +"FCGR1CP" "100132417" +"LINC01132" "100506810" +"TSTD1" "100131187" +"PLA2G2C" "391013" +"RIMS3" "9783" +"PCDH19" "57526" +"SOAT1" "6646" +"FAM226B" "653687" +"TMEM63A" "9725" +"MIR34A" "407040" +"CT55" "54967" +"ERICH3" "127254" +"HMGN2" "3151" +"SELP" "6403" +"SYP" "6855" +"LOC100130417" "100130417" +"GFI1" "2672" +"PNMA3" "29944" +"VASH2" "79805" +"OR2T11" "127077" +"PRMT6" "55170" +"TDRD10" "126668" +"TMSB15B" "286527" +"RPF1" "80135" +"LINC01347" "731275" +"MORF4L2" "9643" +"PAPPA2" "60676" +"SSX1" "6756" +"ARHGEF16" "27237" +"FGF16" "8823" +"OR2L1P" "26247" +"MFAP2" "4237" +"AMPD1" "270" +"ESPNP" "284729" +"LHX4" "89884" +"CD247" "919" +"LCE5A" "254910" +"FBXO44" "93611" +"STX12" "23673" +"GAGE4" "2576" +"SPRR1A" "6698" +"MIR557" "693142" +"NAP1L3" "4675" +"TGFB2-AS1" "728463" +"EVA1B" "55194" +"GLUL" "2752" +"PADI1" "29943" +"ABCA4" "24" +"FBXO2" "26232" +"LAMC1" "3915" +"PTPRF" "5792" +"CSMD2" "114784" +"PRDX1" "5052" +"H2BFWT" "158983" +"GSTM5" "2949" +"NFIA" "4774" +"ACOT11" "26027" +"UBE2DNL" "100131816" +"LCE2B" "26239" +"IVL" "3713" +"DRP2" "1821" +"EPHA8" "2046" +"ZNF644" "84146" +"TMEM51" "55092" +"OR2L2" "26246" +"SHISAL2A" "348378" +"SPANXN4" "441525" +"OR2B11" "127623" +"KCNA10" "3744" +"MIR4253" "100422914" +"MSN" "4478" +"HES2" "54626" +"IGSF21" "84966" +"EPHB2" "2048" +"B3GALNT2" "148789" +"CYSLTR1" "10800" +"MIR421" "693122" +"PAGE2" "203569" +"SNORA59B" "677882" +"KLHDC9" "126823" +"POF1B" "79983" +"ITPKB" "3707" +"ZDHHC9" "51114" +"PPIE" "10450" +"TBC1D25" "4943" +"SLC2A7" "155184" +"MIR509-1" "574514" +"CDC7" "8317" +"SNHG3" "8420" +"OR10J1" "26476" +"LRRC71" "149499" +"LCE2D" "353141" +"FAM167B" "84734" +"OR6F1" "343169" +"OR6K6" "128371" +"SIPA1L2" "57568" +"DMRTB1" "63948" +"GPR3" "2827" +"ZSCAN20" "7579" +"MMEL1" "79258" +"MIR1182" "100302132" +"NKAPP1" "158801" +"PRDM16" "63976" +"TRO" "7216" +"MIR452" "574412" +"AWAT2" "158835" +"CADM3" "57863" +"CYP4B1" "1580" +"NEGR1" "257194" +"SMIM10L2A" "399668" +"KIF17" "57576" +"MIR448" "554212" +"MAGED4B" "81557" +"CYLC1" "1538" +"PFKFB1" "5207" +"PCNX2" "80003" +"INSRR" "3645" +"HAO2" "51179" +"SNORA14B" "677802" +"TESK2" "10420" +"PDIA3P1" "171423" +"PCYT1B" "9468" +"GREM2" "64388" +"DISC1" "27185" +"LINGO4" "339398" +"CPXCR1" "53336" +"FAM72A" "729533" +"NPHS2" "7827" +"ANOS1" "3730" +"TNNT2" "7139" +"MAGEA8" "4107" +"LINC01354" "100506795" +"GPR153" "387509" +"RHOXF1" "158800" +"IL1RAPL2" "26280" +"IRAK1" "3654" +"PAK3" "5063" +"GPR143" "4935" +"WAS" "7454" +"ZCCHC11" "23318" +"PIGA" "5277" +"RRP15" "51018" +"RAB4A" "5867" +"GAGE12J" "729396" +"DCST1-AS1" "100505666" +"SPANXN2" "494119" +"MIR1468" "100302115" +"FLJ44635" "392490" +"TLR7" "51284" +"LINC01140" "339524" +"AWAT1" "158833" +"ADGRL4" "64123" +"TTTY10" "246119" +"PPP1R2P9" "80316" +"GRIK3" "2899" +"ELAVL4" "1996" +"ACTRT1" "139741" +"CNGA2" "1260" +"LEPROT" "54741" +"ERRFI1" "54206" +"PAX7" "5081" +"VCX" "26609" +"PIM2" "11040" +"PLPP3" "8613" +"PEX10" "5192" +"PRKY" "5616" +"FCGR2A" "2212" +"LCE1F" "353137" +"GCSAML" "148823" +"ENO1" "2023" +"TRIM17" "51127" +"OFD1" "8481" +"SSX6" "280657" +"HYI" "81888" +"XAGE1B" "653220" +"RWDD3" "25950" +"EBP" "10682" +"GJA4" "2701" +"SCNN1D" "6339" +"LINC00632" "286411" +"SLC6A14" "11254" +"ETV3" "2117" +"GPC3" "2719" +"MIR3620" "100500810" +"CLDN34" "100288814" +"KANK4" "163782" +"CXorf36" "79742" +"ZBTB8A" "653121" +"MCOLN3" "55283" +"RBM41" "55285" +"CACNA1F" "778" +"LDOC1" "23641" +"FAM46B" "115572" +"GJB4" "127534" +"EPHA10" "284656" +"ARMCX1" "51309" +"SLC26A9" "115019" +"CT45A1" "541466" +"C1orf162" "128346" +"GON4L" "54856" +"TLR5" "7100" +"KIAA1210" "57481" +"MIR551A" "693135" +"INGX" "27160" +"MAGEB1" "4112" +"DPYD" "1806" +"ARSD" "414" +"POU3F4" "5456" +"FOXD2-AS1" "84793" +"CCDC30" "728621" +"ZMYM1" "79830" +"ZNF75D" "7626" +"ARHGEF10L" "55160" +"MAGEB10" "139422" +"ZNF691" "51058" +"PCP4L1" "654790" +"COX20" "116228" +"OR2T34" "127068" +"HDAC1" "3065" +"MIR29C" "407026" +"CPT2" "1376" +"STARD8" "9754" +"MIR5008" "100847072" +"MARCKSL1" "65108" +"PIGK" "10026" +"RTL3" "203430" +"RAB33A" "9363" +"FAM110D" "79927" +"KIF1B" "23095" +"DRAXIN" "374946" +"ACKR1" "2532" +"SPRR2E" "6704" +"BRINP3" "339479" +"MASP2" "10747" +"PADI2" "11240" +"SYT6" "148281" +"SPATA6" "54558" +"NUDT11" "55190" +"SAMD11" "148398" +"AGTR2" "186" +"LINC01278" "92249" +"C1orf53" "388722" +"FAM71A" "149647" +"OR14I1" "401994" +"CHIT1" "1118" +"GABRD" "2563" +"SELE" "6401" +"BCAN" "63827" +"MIR3658" "100500832" +"SHE" "126669" +"PIFO" "128344" +"MIR502" "574504" +"TBL1X" "6907" +"LOC389906" "389906" +"KIF26B" "55083" +"TCEAL1" "9338" +"AKR7A3" "22977" +"TCEANC" "170082" +"CCNB3" "85417" +"INTS6L" "203522" +"ZNF695" "57116" +"CHD1L" "9557" +"TMEM52" "339456" +"LINC01281" "286442" +"PNPLA4" "8228" +"PDPN" "10630" +"RLF" "6018" +"S100A7" "6278" +"DNAJA1P5" "94236" +"DLG3" "1741" +"RGS8" "85397" +"MAGEA6" "4105" +"SMPX" "23676" +"HSD52" "729467" +"MAGEA3" "4102" +"DCAF8L1" "139425" +"CDA" "978" +"OR6N1" "128372" +"GPR25" "2848" +"ZNF362" "149076" +"DNM3" "26052" +"GAGE1" "2543" +"ROR1" "4919" +"CNST" "163882" +"AMMECR1" "9949" +"PLA2G2F" "64600" +"MFSD4A" "148808" +"CT45A5" "441521" +"ATF3" "467" +"ZNF711" "7552" +"PRDM2" "7799" +"SLC25A3P1" "163742" +"SYNC" "81493" +"PTBP2" "58155" +"CHIAP2" "149620" +"VANGL1" "81839" +"PLEKHG5" "57449" +"PDE4B" "5142" +"LOC388692" "388692" +"SPRR4" "163778" +"PUSL1" "126789" +"LOC284578" "284578" +"KLHL4" "56062" +"SYTL4" "94121" +"DEGS1" "8560" +"MIR190B" "100126346" +"PIK3R3" "8503" +"TBL1Y" "90665" +"ZBED6" "100381270" +"BEX3" "27018" +"INE1" "8552" +"DLEU2L" "79469" +"FCN3" "8547" +"REPS2" "9185" +"COLGALT2" "23127" +"C1orf74" "148304" +"PDZD4" "57595" +"UBE2U" "148581" +"ZCCHC12" "170261" +"HMCN1" "83872" +"GSTM4" "2948" +"PHLDA3" "23612" +"SPOCD1" "90853" +"POGZ" "23126" +"ZBTB17" "7709" +"NKRF" "55922" +"TTTY22" "252954" +"OR2T1" "26696" +"TMEM54" "113452" +"LPGAT1" "9926" +"FLG2" "388698" +"CHRNB2" "1141" +"TMEM53" "79639" +"ZC3H12B" "340554" +"PCSK1N" "27344" +"RBM3" "5935" +"UPRT" "139596" +"FAM213B" "127281" +"ELF4" "2000" +"TEX46" "729059" +"SKI" "6497" +"IFI44" "10561" +"VCAM1" "7412" +"RPS10P7" "376693" +"ARHGEF9" "23229" +"STMN1" "3925" +"PRR32" "100130613" +"RAP1GAP" "5909" +"CSF3R" "1441" +"MIA3" "375056" +"CNR2" "1269" +"EIF1AY" "9086" +"TRIM45" "80263" +"WNK3" "65267" +"NPR1" "4881" +"PIH1D3" "139212" +"PLA2G2E" "30814" +"C1orf94" "84970" +"COG2" "22796" +"TSPAN2" "10100" +"OR6P1" "128366" +"HIVEP3" "59269" +"SLC35F3" "148641" +"FHAD1" "114827" +"GPR161" "23432" +"NDUFB11" "54539" +"SCML1" "6322" +"PALMD" "54873" +"AIM2" "9447" +"NEK2" "4751" +"CACHD1" "57685" +"OR10Z1" "128368" +"NBL1" "4681" +"SEMA4A" "64218" +"MAGEC1" "9947" +"SSX8" "280659" +"CCDC17" "149483" +"DGAT2L6" "347516" +"C2CD4D" "100191040" +"DUSP21" "63904" +"TLR8-AS1" "349408" +"ZP4" "57829" +"FMN2" "56776" +"RBBP7" "5931" +"SPEN" "23013" +"PJA1" "64219" +"AGO4" "192670" +"PLA2G2D" "26279" +"CDX4" "1046" +"RHD" "6007" +"KCNT2" "343450" +"BMP8B" "656" +"ARMCX2" "9823" +"SRPX" "8406" +"PSMB2" "5690" +"USP11" "8237" +"SLC44A5" "204962" +"DHRS3" "9249" +"NUP62CL" "54830" +"LINC00630" "100287765" +"HSPA7" "3311" +"DDX53" "168400" +"FCMR" "9214" +"BCL9" "607" +"GAGE2C" "2574" +"HIST2H2BF" "440689" +"SSX3" "10214" +"UBA1" "7317" +"HSD3B2" "3284" +"PFDN2" "5202" +"G0S2" "50486" +"MNDA" "4332" +"PLPPR5" "163404" +"NLGN4Y" "22829" +"MAGEA10" "4109" +"MTMR9LP" "339483" +"SPIN2A" "54466" +"MAGIX" "79917" +"CRYBG2" "55057" +"SLC38A5" "92745" +"XRCC6P5" "442459" +"LGALS8-AS1" "100287902" +"ASB11" "140456" +"LINC01139" "339535" +"SMYD2" "56950" +"LINC00891" "441501" +"COA6" "388753" +"SLC25A43" "203427" +"ZFY" "7544" +"OR2T12" "127064" +"TNR" "7143" +"B3GALT2" "8707" +"TNFRSF1B" "7133" +"TMEM88B" "643965" +"C1orf185" "284546" +"CAPN6" "827" +