Mercurial > repos > miller-lab > genome_diversity
annotate offspring_heterozygosity_pedigree.py @ 32:03c22b722882
remove BeautifulSoup dependency
author | Richard Burhans <burhans@bx.psu.edu> |
---|---|
date | Fri, 20 Sep 2013 13:54:23 -0400 |
parents | a631c2f6d913 |
children |
rev | line source |
---|---|
31
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
1 #!/usr/bin/env python |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
2 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
3 import sys |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
4 import gd_util |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
5 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
6 from Population import Population |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
7 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
8 def load_and_check_pop(file, total_pop, name): |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
9 p = Population() |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
10 p.from_population_file(file) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
11 if not total_pop.is_superset(p): |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
12 gd_util.die('There is an individual in the {0} that is not in the SNP table'.format(name)) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
13 return p |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
14 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
15 def append_breeders_from_file(the_list, filename, kind): |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
16 with open(filename) as fh: |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
17 for line in fh: |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
18 elems = line.split() |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
19 breeder = elems[0].rstrip('\r\n') |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
20 the_list.append('{0}:{1}'.format(kind, breeder)) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
21 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
22 ################################################################################ |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
23 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
24 if len(sys.argv) != 9: |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
25 gd_util.die('Usage') |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
26 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
27 input, input_type, pedigree, ind_arg, founders, b1_input, b2_input, output = sys.argv[1:] |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
28 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
29 p_total = Population() |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
30 p_total.from_wrapped_dict(ind_arg) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
31 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
32 f1 = load_and_check_pop(founders, p_total, 'founders') |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
33 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
34 ################################################################################ |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
35 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
36 prog = 'offspring_heterozygosity2' |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
37 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
38 args = [ prog ] |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
39 args.append(input) # a Galaxy SNP table |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
40 args.append(pedigree) # a pedigree, where the SNP table is for the founders |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
41 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
42 for tag in f1.tag_list(): |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
43 column, name = tag.split(':') |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
44 if type == 'gd_genotype': |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
45 column = int(column) - 2 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
46 tag = 'founder:{0}:{1}'.format(column, name) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
47 args.append(tag) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
48 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
49 append_breeders_from_file(args, b1_input, 0) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
50 append_breeders_from_file(args, b2_input, 1) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
51 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
52 with open(output, 'w') as fh: |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
53 gd_util.run_program(prog, args, stdout=fh) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
54 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
55 ################################################################################ |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
56 |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
57 sys.exit(0) |
a631c2f6d913
Update to Miller Lab devshed revision 3c4110ffacc3
Richard Burhans <burhans@bx.psu.edu>
parents:
diff
changeset
|
58 |