Mercurial > repos > miller-lab > genome_diversity
diff find_intervals.xml @ 12:4b6590dd7250
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author | miller-lab |
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date | Wed, 12 Sep 2012 17:10:26 -0400 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/find_intervals.xml Wed Sep 12 17:10:26 2012 -0400 @@ -0,0 +1,100 @@ +<tool id="gd_find_intervals" name="Find remarkable" version="1.0.0"> + <description>genomic intervals</description> + + <command interpreter="python"> + find_intervals.py "$input" "$input.metadata.dbkey" "$output" "$output.files_path" + + #if $override_metadata.choice == "0" + "$input.metadata.ref" "$input.metadata.rPos" + #else + "$override_metadata.ref_col" "$override_metadata.rpos_col" + #end if + + "$score_col" "$shuffles" + + #if $cutoff.type == 'percentage' + "$cutoff.cutoff_pct" + #else + "=$cutoff.cutoff_val" + #end if + + "$out_format" + </command> + + <inputs> + <param name="input" type="data" format="tabular" label="Input"> + <validator type="unspecified_build" message="This dataset does not have a reference species and cannot be used with this tool" /> + </param> + + <param name="score_col" type="data_column" data_ref="input" numerical="true" label="Column with score"/> + + <conditional name="cutoff"> + <param name="type" type="select" label="Cutoff type"> + <option value="percentage">percentage</option> + <option value="value">value</option> + </param> + <when value="percentage"> + <param name="cutoff_pct" type="float" value="95" min="0" max="100" label="Percentage cutoff"/> + </when> + <when value="value"> + <param name="cutoff_val" type="float" value="0.0" label="Value cutoff"/> + </when> + </conditional> + + <param name="shuffles" type="integer" min="0" value="0" label="Number of randomizations"/> + + <param name="out_format" type="select" format="integer" label="Report SNPs"> + <option value="0" selected="true">No</option> + <option value="1">Yes</option> + </param> + + <conditional name="override_metadata"> + <param name="choice" type="select" format="integer" label="Choose columns"> + <option value="0" selected="true">No, get columns from metadata</option> + <option value="1" >Yes, choose columns</option> + </param> + <when value="0" /> + <when value="1"> + <param name="ref_col" type="data_column" data_ref="input" numerical="false" label="Column with reference chromosome"/> + <param name="rpos_col" type="data_column" data_ref="input" numerical="true" label="Column with reference position"/> + </when> + </conditional> + </inputs> + + <outputs> + <data name="output" format="interval"> + <change_format> + <when input="out_format" value="1" format="bigwigpos" /> + </change_format> + </data> + </outputs> + + <tests> + <test> + <param name="input" value="test_in/sample.gd_snp" ftype="gd_snp" /> + <param name="score_col" value="5" /> + <param name="type" value="value" /> + <param name="cutoff_val" value="700.0" /> + <param name="shuffles" value="10" /> + <param name="out_format" value="0" /> + <param name="choice" value="0" /> + + <output name="output" file="test_out/find_intervals/find_intervals.interval" /> + </test> + </tests> + + <help> +**What it does** + +The user selects a SNP table and specifies the columns containing (1) +chromosome, (2) position, (3) scores (such as an Fst-value for the SNP), (4) +a percentage or raw score for the "cutoff" and (5) the number of times the +data should be randomized (only intervals with score exceeding the maximum for +the randomized data are reported). If a percentage (e.g. 95%) is specified +for #3, then that percentile of the scores is used as the cutoff; this may +not work well if many SNPs have the same score. The program subtracts the +cutoff from every score, then finds genomic intervals (i.e., consecutive runs +of SNPs) whose total score cannot be increased by adding or subtracting one +or more SNPs at the ends of the interval. + </help> +</tool>