Mercurial > repos > miller-lab > genome_diversity
diff coverage_distributions.xml @ 17:a3af29edcce2
Uploaded Miller Lab Devshed version a51c894f5bed
author | miller-lab |
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date | Fri, 28 Sep 2012 11:57:18 -0400 |
parents | 8ae67e9fb6ff |
children | f04f40a36cc8 |
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--- /dev/null Thu Jan 01 00:00:00 1970 +0000 +++ b/coverage_distributions.xml Fri Sep 28 11:57:18 2012 -0400 @@ -0,0 +1,122 @@ +<tool id="gd_coverage_distributions" name="Coverage Distributions" version="1.0.0"> + <description>: Examine sequence coverage for SNPs</description> + + <command interpreter="python"> + coverage_distributions.py "$input" "0" "$output" "$output.files_path" + #if $individuals.choice == '0' + "all_individuals" + #else if $individuals.choice == '1' + #set $arg = 'individuals:%s' % str($individuals.p1_input) + "$arg" + #else if $individuals.choice == '2' + #for $population in $individuals.populations + #set $arg = 'population:%s:%s' % (str($population.p_input), str($population.p_input.name)) + "$arg" + #end for + #end if + #for $individual, $individual_col in zip($input.dataset.metadata.individual_names, $input.dataset.metadata.individual_columns) + #set $individual_arg = 'individual:%s:%s' % ($individual_col, $individual) + "$individual_arg" + #end for + </command> + + <inputs> + <param name="input" type="data" format="gd_snp" label="SNP dataset" /> + + <conditional name="individuals"> + <param name="choice" type="select" label="Compute for"> + <option value="0" selected="true">All individuals</option> + <option value="1">Individuals in a population</option> + <option value="2">Totals of populations</option> + </param> + <when value="0" /> + <when value="1"> + <param name="p1_input" type="data" format="gd_indivs" label="Population individuals" /> + </when> + <when value="2"> + <repeat name="populations" title="Population" min="1"> + <param name="p_input" type="data" format="gd_indivs" label="individuals" /> + </repeat> + </when> + </conditional> + + <!-- + <param name="data_source" type="select" label="Data source"> + <option value="0" selected="true">Sequence coverage</option> + <option value="1">Genotype quality</option> + </param> + --> + </inputs> + + <outputs> + <data name="output" format="html" /> + </outputs> + + <tests> + <test> + <param name="input" value="test_in/sample.gd_snp" ftype="gd_snp" /> + <param name="choice" value="0" /> + <output name="output" file="test_out/coverage_distributions/coverage.html" ftype="html" compare="diff" lines_diff="2"> + <extra_files type="file" name="coverage.pdf" value="test_out/coverage_distributions/coverage.pdf" compare="sim_size" delta = "1000"/> + <extra_files type="file" name="coverage.txt" value="test_out/coverage_distributions/coverage.txt" /> + </output> + </test> + </tests> + + <help> + +**Dataset formats** + +The input dataset is in gd_snp_ format. +The output is a composite dataset, containing both a text table and a PDF plot. +(`Dataset missing?`_) + +.. _gd_snp: ./static/formatHelp.html#gd_snp +.. _Dataset missing?: ./static/formatHelp.html + +----- + +**What it does** + +This tool reports distributions of a SNP reliability indicator, in this case +sequence coverage, for individuals or populations. +The coverage can be computed for all individuals, a subset of individuals, +or totals for populations defined by the Specify Individuals tool. +The results are reported as a text table giving the cumulative distributions, +and as a plot. + +----- + +**Examples** + +- input:: + + chr1 14929 A G 999 21 30 1 127 7 11 1 28 7 29 0 5 2 5 1 17 10 14 1 81 17 74 1 42 15 22 1 125 29 84 1 88 6 10 1 11 30 23 1 79 19 1 2 71 24 0 2 99 41 10 2 2 + chr1 17451 C T 6.88 119 1 2 255 12 0 2 63 35 0 2 59 14 0 2 72 19 1 2 57 101 1 2 255 38 8 1 20 125 0 2 255 13 0 2 62 42 0 2 51 44 0 2 64 26 0 2 108 59 0 2 194 + chr1 30922 G T 999 0 23 0 66 0 0 -1 0 0 0 -1 0 0 0 -1 0 0 2 0 3 0 14 0 39 14 16 1 153 0 45 0 132 6 0 2 48 19 0 2 87 3 0 2 32 0 0 -1 0 0 0 -1 0 + etc. + +- text output:: + + 0 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 + John West 0 0 0 0 0 0 0 0 1 1 1 1 2 2 3 3 4 4 5 6 + NA12892 0 2 5 11 20 31 43 55 67 77 84 90 93 96 97 98 99 99 99 99 + NA12891 0 0 0 0 0 1 1 2 3 5 6 9 11 15 19 23 29 35 41 47 + NA12249 1 4 11 23 38 54 68 79 88 93 96 98 99 99 99 99 99 99 99 99 + NA12342 0 0 1 1 2 4 6 9 13 18 23 29 36 43 50 58 65 71 77 82 + KB1 0 0 0 0 0 0 0 0 0 0 0 0 1 1 1 1 1 1 2 2 + ABT 0 0 0 0 0 0 1 1 1 2 3 4 5 6 8 10 12 14 18 21 + NA18507 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 + NA19238 0 0 0 1 2 4 6 10 14 19 25 32 39 47 55 62 69 76 81 86 + NA19239 0 0 0 0 1 1 2 4 5 8 11 15 19 24 31 37 44 51 58 65 + YH 2 4 6 7 8 8 9 10 11 12 14 17 19 22 25 29 32 36 40 45 + KOREAN 0 0 1 1 3 4 5 7 10 12 15 19 22 27 31 37 42 48 54 60 + JPT 0 0 0 0 0 0 0 0 1 1 1 2 2 3 4 5 7 8 10 12 + etc. + +graphical output: + +.. image:: ${static_path}/images/gd_coverage.png + + </help> +</tool>