Mercurial > repos > miller-lab > genome_diversity
view find_intervals.py @ 0:2c498d40ecde
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author | miller-lab |
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date | Mon, 09 Apr 2012 12:03:06 -0400 |
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#!/usr/bin/env python import errno import os import subprocess import sys ################################################################################ def mkdir_p(path): try: os.makedirs(path) except OSError, e: if e.errno <> errno.EEXIST: raise def run_program(prog, args, stdout_file=None): #print "args:", ' '.join(args) p = subprocess.Popen(args, bufsize=-1, executable=prog, stdin=None, stdout=subprocess.PIPE, stderr=subprocess.PIPE) (stdoutdata, stderrdata) = p.communicate() rc = p.returncode if stdout_file is not None: with open(stdout_file, 'w') as ofh: print >> ofh, stdoutdata.rstrip('\r\n') if rc != 0: print >> sys.stderr, "FAILED: rc={0}: {1}".format(rc, ' '.join(args)) print >> sys.stderr, stderrdata sys.exit(1) ################################################################################ if len(sys.argv) != 11: print "usage" sys.exit(1) input, dbkey, output, output_files_path, chrom_col, pos_col, score_col, shuffles, cutoff, report_snps = sys.argv[1:11] prog = 'sweep' args = [ prog ] args.append(input) args.append(chrom_col) args.append(pos_col) args.append(score_col) args.append(cutoff) args.append(shuffles) args.append(report_snps) run_program(None, args, stdout_file=output) if report_snps == "0": sys.exit(0) ################################################################################ mkdir_p(output_files_path) bedgraph_filename = 'bedgraph.txt' links_filename = os.path.join(output_files_path, 'links.txt') data = [] links_data = [] with open(output) as fh: chrom = None for line in fh: line = line.rstrip('\r\n') if not line: continue if line[0] != ' ': # chrom line, add a link chrom, interval_begin, interval_end, interval_value = line.split('\t') links_data.append((chrom, int(interval_begin), int(interval_end))) else: # data line, add a bedgraph line begin, value = line.split() data.append((chrom, int(begin), value)) with open(bedgraph_filename, 'w') as ofh: print >> ofh, 'track type=bedGraph' for chrom, begin, value in sorted(data): print >> ofh, chrom, begin, begin+1, value with open(links_filename, 'w') as ofh: for chrom, begin, end in sorted(links_data): print >> ofh, chrom, begin, end ################################################################################ chrom_sizes_filename = '{0}.chrom.sizes'.format(dbkey) prog = 'fetchChromSizes' args = [ prog ] args.append(dbkey) run_program(None, args, stdout_file=chrom_sizes_filename) ################################################################################ prog = 'bedGraphToBigWig' args = [ prog ] args.append(bedgraph_filename) args.append(chrom_sizes_filename) args.append(output) run_program(None, args) ################################################################################ sys.exit(0)